47 CFR Alphabetical Index - Part 78

Science.gov (United States)

2010-10-01

... 47 Telecommunication 4 2010-10-01 2010-10-01 false Part 78 Index Alphabetical Index... SERVICE Technical Regulations Modulation limits. Pt. 78, Index Alphabetical Index—Part 78 A Antenna... Changes in equipment 78.109 Conditions for license 78.27 Coordination, frequencies 78.36 Cross reference...

A Note on Sequence Prediction over Large Alphabets

Directory of Open Access Journals (Sweden)

Travis Gagie

2012-02-01

Full Text Available Building on results from data compression, we prove nearly tight bounds on how well sequences of length n can be predicted in terms of the size σ of the alphabet and the length k of the context considered when making predictions. We compare the performance achievable by an adaptive predictor with no advance knowledge of the sequence, to the performance achievable by the optimal static predictor using a table listing the frequency of each (k + 1-tuple in the sequence. We show that, if the elements of the sequence are chosen uniformly at random, then an adaptive predictor can compete in the expected case if k ≤ logσ n – 3 – ε, for a constant ε > 0, but not if k ≥ logσ n.

Writing Kurdish Alphabetics in Java Programming Language

OpenAIRE

Rebwar Mala Nabi; Sardasht M-Raouf Mahmood; Mohammed Qadir Kheder; Shadman Mahmood

2016-01-01

Nowadays, Kurdish programmers usually suffer when they need to write Kurdish letter while they program in java. More to say, all the versions of Java Development Kits have not supported Kurdish letters. Therefore, the aim of this study is to develop Java Kurdish Language Package (JKLP) for solving writing Kurdish alphabetic in Java programming language. So that Kurdish programmer and/or students they can converts the English-alphabetic to Kurdish-alphabetic. Furthermore, adding Kurdish langua...

ALPHABETS OF THE MODERN SLAVIC LANGUAGES.

Science.gov (United States)

BIDWELL, CHARLES E.

THE TABLES AND ACCOMPANYING EXPLANATIONS IN THIS OUTLINE ARE INTENDED FOR THE NON-SPECIALIST IN SLAVIC LANGUAGES WHO WISHES TO LEARN THE APPROXIMATE PRONUNCIATION AND TRANSLITERATION OF WORDS WRITTEN IN THE SLAVIC ALPHABET. EACH ALPHABET TREATED (CZECH, RUSSIAN, UKRAINIAN, BIELORUSSIAN, BULGARIAN, SLOVENIAN, SERBO-CROATIAN, POLISH, CHURCH SLAVIC,…

K-12 Education

Science.gov (United States)

products laboratories publications nisee b.i.p. members education FAQs links education Education Program Internships K-12 Education Contact the PEER Education Program PEER's Educational Affiliates Student Design Competition Student Leadership Council Classes and Other Educational Activities Site Map Search K-12 Education

Decoding the Assessment Alphabet Soup

Science.gov (United States)

Engelhardt, Paula

2010-10-01

The number of assessment instruments that help physics instructors evaluate the conceptual learning of their students has grown over the last twenty years. Today, the number of tests that are available begin to look like an alphabet soup, FCI, MBT, TUG-K, CSE, CSM, CSEM, DIRECT, BEMA, LOCE, FMCE, SEMCO, etc. What can these assessment tests do for you that is different from what you regularly do? How do these tests differ from the tests and other assessments you already give in class? What is meant by formative and summative assessment and why should you care? What are some of the issues associated with giving one of these assessment tests? These are the questions that will be addressed in this talk.

Applying the Quadratic Usage Framework to Research on K-12 STEM Digital Learning Resources

Science.gov (United States)

Luetkemeyer, Jennifer R.

2016-01-01

Numerous policymakers have called for K-12 educators to increase their effectiveness by transforming science, technology, engineering, and mathematics (STEM) learning and teaching with digital resources and tools. In this study we outline the significance of studying pressing issues related to use of digital resources in the K-12 environment and…

The Alphabet of the Universe

CERN Multimedia

Antonella Del Rosso

2015-01-01

One of the most culturally inspiring – yet unexpected – venues where you can find an exhibition about CERN and particle physics these days is the Bibliotheca Alexandrina in Egypt. Discover The Alphabet of the Universe: from CERN to North Africa and the Middle East in the cradle of knowledge par excellence.   The Alphabet of the Universe exhibition in Alexandria. (Image credit: Bibliotheca Alexandrina) With its 400 square metres surface area, about 40 exhibits and more than 50 people involved, The Alphabet of the Universe exhibition was inaugurated on 19 January in the Planetarium Science Centre (PSC), one of the main attractions of the New Library of Alexandria. “The exhibition has been designed to cover four main themes related to particle physics and CERN: what we know; open issues; accelerators and detectors; computing and applications,” explains Barbara Gallavotti, curator of the exhibition. “The exhibits were designed b...

K-12 STEM Educators and the Inclusive Classroom

OpenAIRE

Li, Songze

2016-01-01

The United States public schools promote inclusion and educational equity among diverse student populations. Considerable and growing numbers of students with categorical disabilities and Limited English Proficiency (LEP) are enrolled in regular classrooms. The systemic barriers in learning that they have could impact teacher perceptions and decisions about teaching practices as well as the teaching profession. These students have challenged K-12 science, technology, engineering, and mathemat...

Biomedical and Biochemical Engineering for K-12 Students

Science.gov (United States)

Madihally, Sundararajan V.; Maase, Eric L.

2006-01-01

REACH (Reaching Engineering and Architectural Career Heights) is a weeklong summer academy outreach program for high school students interested in engineering, architecture, or technology. Through module-­based instruction, students are introduced to various engineering fields. This report describes one of the modules focused on introducing…

Structural alphabets derived from attractors in conformational space

Directory of Open Access Journals (Sweden)

Kleinjung Jens

2010-02-01

Full Text Available Abstract Background The hierarchical and partially redundant nature of protein structures justifies the definition of frequently occurring conformations of short fragments as 'states'. Collections of selected representatives for these states define Structural Alphabets, describing the most typical local conformations within protein structures. These alphabets form a bridge between the string-oriented methods of sequence analysis and the coordinate-oriented methods of protein structure analysis. Results A Structural Alphabet has been derived by clustering all four-residue fragments of a high-resolution subset of the protein data bank and extracting the high-density states as representative conformational states. Each fragment is uniquely defined by a set of three independent angles corresponding to its degrees of freedom, capturing in simple and intuitive terms the properties of the conformational space. The fragments of the Structural Alphabet are equivalent to the conformational attractors and therefore yield a most informative encoding of proteins. Proteins can be reconstructed within the experimental uncertainty in structure determination and ensembles of structures can be encoded with accuracy and robustness. Conclusions The density-based Structural Alphabet provides a novel tool to describe local conformations and it is specifically suitable for application in studies of protein dynamics.

Generation of correlated finite alphabet waveforms using gaussian random variables

KAUST Repository

Jardak, Seifallah

2014-09-01

Correlated waveforms have a number of applications in different fields, such as radar and communication. It is very easy to generate correlated waveforms using infinite alphabets, but for some of the applications, it is very challenging to use them in practice. Moreover, to generate infinite alphabet constant envelope correlated waveforms, the available research uses iterative algorithms, which are computationally very expensive. In this work, we propose simple novel methods to generate correlated waveforms using finite alphabet constant and non-constant-envelope symbols. To generate finite alphabet waveforms, the proposed method map the Gaussian random variables onto the phase-shift-keying, pulse-amplitude, and quadrature-amplitude modulation schemes. For such mapping, the probability-density-function of Gaussian random variables is divided into M regions, where M is the number of alphabets in the corresponding modulation scheme. By exploiting the mapping function, the relationship between the cross-correlation of Gaussian and finite alphabet symbols is derived. To generate equiprobable symbols, the area of each region is kept same. If the requirement is to have each symbol with its own unique probability, the proposed scheme allows us that as well. Although, the proposed scheme is general, the main focus of this paper is to generate finite alphabet waveforms for multiple-input multiple-output radar, where correlated waveforms are used to achieve desired beampatterns. © 2014 IEEE.

Engineering Computer Games: A Parallel Learning Opportunity for Undergraduate Engineering and Primary (K-5 Students

Directory of Open Access Journals (Sweden)

Mark Michael Budnik

2011-04-01

Full Text Available In this paper, we present how our College of Engineering is developing a growing portfolio of engineering computer games as a parallel learning opportunity for undergraduate engineering and primary (grade K-5 students. Around the world, many schools provide secondary students (grade 6-12 with opportunities to pursue pre-engineering classes. However, by the time students reach this age, many of them have already determined their educational goals and preferred careers. Our College of Engineering is developing resources to provide primary students, still in their educational formative years, with opportunities to learn more about engineering. One of these resources is a library of engineering games targeted to the primary student population. The games are designed by sophomore students in our College of Engineering. During their Introduction to Computational Techniques course, the students use the LabVIEW environment to develop the games. This software provides a wealth of design resources for the novice programmer; using it to develop the games strengthens the undergraduates

Developing Early Literacy Skills: A Meta-Analysis of Alphabet Learning and Instruction

OpenAIRE

Piasta, Shayne B.; Wagner, Richard K.

2010-01-01

Alphabet knowledge is a hallmark of early literacy and facilitating its development has become a primary objective of pre-school instruction and intervention. However, little agreement exists about how to promote the development of alphabet knowledge effectively. A meta-analysis of the effects of instruction on alphabet outcomes demonstrated that instructional impacts differed by type of alphabet outcome examined and content of instruction provided. School-based instruction yielded larger eff...

The Chem-E-Car as a Vehicle for Service Learning through K-12 Outreach

Science.gov (United States)

Chirdon, William

2017-01-01

This article presents the results of combining the American Institute of Chemical Engineers' (AIChE) Chem-E-Car competition activities with engineering outreach to K-12 students in a service-learning course. Survey results are presented to show how the program develops technical skills as well as leadership, teamwork, and communication skills in…

Universal Partial Words over Non-Binary Alphabets

OpenAIRE

Goeckner, Bennet; Groothuis, Corbin; Hettle, Cyrus; Kell, Brian; Kirkpatrick, Pamela; Kirsch, Rachel; Solava, Ryan

2016-01-01

Chen, Kitaev, M\\"{u}tze, and Sun recently introduced the notion of universal partial words, a generalization of universal words and de Bruijn sequences. Universal partial words allow for a wild-card character $\\diamond$, which is a placeholder for any letter in the alphabet. We settle and strengthen conjectures posed in the same paper where this notion was introduced. For non-binary alphabets, we show that universal partial words have periodic $\\diamond$ structure and are cyclic, and we give ...

High-Rate Field Demonstration of Large-Alphabet Quantum Key Distribution

Science.gov (United States)

2016-10-12

count rate of Bob’s detectors. In this detector-limited regime , it is advantageous to increase M to encode as much information as possible in each...High- rate field demonstration of large-alphabet quantum key distribution Catherine Lee,1, 2 Darius Bunandar,1 Zheshen Zhang,1 Gregory R. Steinbrecher...October 12, 2016) 2 Quantum key distribution (QKD) enables secure symmetric key exchange for information-theoretically secure com- munication via one-time

The Engaged Microbiologist: Bringing the Microbiological Sciences to the K-12 Community.

Science.gov (United States)

Westenberg, David J

2016-03-01

Exposing K-12 students to cutting edge science that impacts their daily lives can bring classroom lessons to life. Citizen-science projects are an excellent way to bring high-level science to the classroom and help satisfy one of the cornerstone concepts of the Next Generation Science Standards (NGSS), "engaging in practices that scientists and engineers actually use." This can be a daunting task for teachers who may lack the background or resources to integrate these projects into the classroom. This is where scientific societies such as the American Society for Microbiology (ASM) can play a critical role. ASM encourages its members to engage with the K-12 community by providing networking opportunities and resources for ASM members and K-12 teachers to work together to bring microbiology into the classroom. Journal of Microbiology & Biology Education.

Soil Science Society of America - K-12 Outreach

Science.gov (United States)

Lindbo, David L.; Loynachan, Tom; Mblia, Monday; Robinson, Clay; Chapman, Susan

2013-04-01

The Soil Science Society of America created its K12 Committee in 2006 in part to compliment the Dig It! The Secrets of Soil exhibit that opened in July 2008 at the Smithsonian's Institution's Nation Museum of Natural History (of which SSS was a founding sponsor). The committee's work began quickly with a website designed to provide resources for K12 teachers. The first accomplishments included reviewing and posting links to web based information already available to teachers. These links were sorted by subject and grade level to make it easier for teachers to navigate the web and find what they needed quickly. Several presentations and lessons designed for K12 teachers were also posted at this time. Concurrent with this effort a subcommittee review and organized the national teaching standards to show where soils could fit into the overall K12 curriculum. As the website was being developed another subcommittee developed a soils book (Soil! Get the Inside Scoop, 2008) to further compliment the Dig It! exhibit. This was a new endeavor for SSSA having never worked with the non-academic audience in developing a book. Peer-reviews of this book included not only scientist but also students in order to make sure the book was attractive to them. Once the book was published and the website developed it became clear more outreach was needed. SSSA K12 Committee has attended both the National Science Teachers Association (since 2008) the USA Science and Engineering Festival (since 2010) with exhibits and workshops. It has cooperated and contributed to the American Geologic Institutes' Earth Science Week materials with brochures and lesson plans and with National Association of Conservation Districts by providing peer-review and distribution of materials. The most recent developments from the committee include a web redesign that is more student and teacher friendly, the development of a peer-review system to publish K12 Lesson Plans, and finally the publication of a new soils

The Development of a Conceptual Framework for New K-12 Science Education Standards (Invited)

Science.gov (United States)

Keller, T.

2010-12-01

The National Academy of Sciences has created a committee of 18 National Academy of Science and Engineering members, academic scientists, cognitive and learning scientists, and educators, educational policymakers and researchers to develop a framework to guide new K-12 science education standards. The committee began its work in January, 2010, released a draft of the framework in July, 2010, and intends to have the final framework in the first quarter of 2011. The committee was helped in early phases of the work by consultant design teams. The framework is designed to help realize a vision for science and engineering education in which all students actively engage in science and engineering practices in order to deepen their understanding of core ideas in science over multiple years of school. These three dimensions - core disciplinary ideas, science and engineering practices, and cross-cutting elements - must blend together to build an exciting, relevant, and forward looking science education. The framework will be used as a base for development of next generation K-12 science education standards.

Nurturing Phonemic Awareness and Alphabetic Knowledge in Pre-Kindergartners.

Science.gov (United States)

Steinhaus, Patricia L.

Reading research continues to identify phonemic awareness and knowledge of the alphabetic principle as key factors in the literacy acquisition process and to indicate that they greatly facilitate decoding efforts. While research indicates that phonemic awareness and alphabetic knowledge are necessary to literacy acquisition, many early childhood…

A multifractal formalism for countable alphabet subshifts

International Nuclear Information System (INIS)

Meson, Alejandro; Vericat, Fernando

2009-01-01

We study here the multifractal spectrum of local entropies for subshifts with an infinite alphabet. The description of this spectrum is obtained from the Legendre transform of a free energy map and Gibbs states associated with adequate potentials. The lack of compactness in the symbolic space necessitates modifications to the description for the compact case, i.e. for finite alphabet. In particular, the class of potentials must be restricted to a narrower one than that considered for the compact case

K-12 Students' Perceptions of Scientists: Finding a Valid Measurement and Exploring Whether Exposure to Scientists Makes an Impact

Science.gov (United States)

Hillman, Susan J.; Bloodsworth, Kylie H.; Tilburg, Charles E.; Zeeman, Stephan I.; List, Henrietta E.

2014-01-01

This study was launched from a National Science Foundation GK-12 grant in which graduate fellows in Science, Technology, Engineering, and Mathematics (STEM) are placed in classrooms to engage K-12 students in STEM activities. The investigation explored whether the STEM Fellows' presence impacted the K-12 students' stereotypical image of a…

An Interactive Augmented Reality Implementation of Hijaiyah Alphabet for Children Education

Science.gov (United States)

Rahmat, R. F.; Akbar, F.; Syahputra, M. F.; Budiman, M. A.; Hizriadi, A.

2018-03-01

Hijaiyah alphabet is letters used in the Qur’an. An attractive and exciting learning process of Hijaiyah alphabet is necessary for the children. One of the alternatives to create attractive and interesting learning process of Hijaiyah alphabet is to develop it into a mobile application using augmented reality technology. Augmented reality is a technology that combines two-dimensional or three-dimensional virtual objects into actual three-dimensional circles and projects them in real time. The purpose of application aims to foster the children interest in learning Hijaiyah alphabet. This application is using Smartphone and marker as the medium. It was built using Unity and augmented reality library, namely Vuforia, then using Blender as the 3D object modeling software. The output generated from this research is the learning application of Hijaiyah letters using augmented reality. How to use it is as follows: first, place marker that has been registered and printed; second, the smartphone camera will track the marker. If the marker is invalid, the user should repeat the tracking process. If the marker is valid and identified, the marker will have projected the objects of Hijaiyah alphabet in three-dimensional form. Lastly, the user can learn and understand the shape and pronunciation of Hijaiyah alphabet by touching the virtual button on the marker

Math, Science, and Engineering Integration in a High School Engineering Course: A Qualitative Study

Science.gov (United States)

Valtorta, Clara G.; Berland, Leema K.

2015-01-01

Engineering in K-12 classrooms has been receiving expanding emphasis in the United States. The integration of science, mathematics, and engineering is a benefit and goal of K-12 engineering; however, current empirical research on the efficacy of K-12 science, mathematics, and engineering integration is limited. This study adds to this growing…

On alphabetic presentations of Clifford algebras and their possible applications

NARCIS (Netherlands)

Toppan, F.; Verbeek, P.W.

2009-01-01

In this paper, we address the problem of constructing a class of representations of Clifford algebras that can be named “alphabetic (re)presentations.” The Clifford algebra generators are expressed as m-letter words written with a three-character or a four-character alphabet. We formulate the

Investigation of Problem Solving Skills among 12th Grade Engineering Students

OpenAIRE

Shanta, Susheela

2017-01-01

US competitiveness in the 21st century global economy depends on a workforce that is science, technology, engineering and mathematics (STEM) literate, and has knowledge and skills to tackle complex technological problems. In response to the need for a STEM literate workforce equipped with 21st century skills there is a push for K-12 educational reform. STEM literacy is the ability to use content knowledge and skills in science, technology, engineering and math in solving human problems in a c...

Development of Problem Sets for K-12 and Engineering on Pharmaceutical Particulate Systems

Science.gov (United States)

Savelski, Mariano J.; Slater, C. Stewart; Del Vecchio, Christopher A.; Kosteleski, Adrian J.; Wilson, Sarah A.

2010-01-01

Educational problem sets have been developed on structured organic particulate systems (SOPS) used in pharmaceutical technology. The sets present topics such as particle properties and powder flow and can be integrated into K-12 and college-level curricula. The materials educate students in specific areas of pharmaceutical particulate processing,…

Alphabetical order effects in school admissions

Czech Academy of Sciences Publication Activity Database

Jurajda, Štěpán; Münich, Daniel

2016-01-01

Roč. 31, č. 4 (2016), s. 483-498 ISSN 0267-1522 Institutional support: PRVOUK-P23 Keywords : admissions * alphabetical order * order effects Subject RIV: AH - Economics Impact factor: 1.033, year: 2016

40 kW Stirling Engine for Solid Fuel

DEFF Research Database (Denmark)

Carlsen, Henrik; Trærup, Jens

1996-01-01

The external combustion in a Stirling engine makes it very attractive for utilisation of solid fuels in decentralised combined heat and power (CHP) plants. Only a few projects have concentrated on the development of Stirling engines specifically for biomass. In this project, a Stirling engine has...... been designed primarily for utilisation of wood chips. Maximum shaft power is 40 kW corresponding to an electric output of 36 kW. Biomass needs more space in the combustion chamber compared to gas and liquid fuels, and a large heat transfer area is necessary. The design of the new Stirling engine has...... been adapted to the special demands of combustion of wood chips, resulting in a large engine compared to engines for gas or liquid fuels. The engine has four-cylinders arranged in a square. The design is made as a hermetic unit, where the alternator is built into the pressurised crankcase so...

46 CFR 12.15-13 - Deck engine mechanic.

Science.gov (United States)

2010-10-01

... 46 Shipping 1 2010-10-01 2010-10-01 false Deck engine mechanic. 12.15-13 Section 12.15-13 Shipping... ENDORSEMENTS Qualified Member of the Engine Department § 12.15-13 Deck engine mechanic. (a) An applicant for an endorsement as deck engine mechanic shall be a person holding an MMC or MMD endorsed as junior engineer. The...

Reflections of Debates Upon Alphabet (Letter to Journal of Sebilürreşad

Directory of Open Access Journals (Sweden)

Mehmet Soğukömeroğulları

2014-12-01

Full Text Available In Otoman State which had used Arabic alphabet until a certain period the issue of writing in Latin alphabet was gained currency thanks to the students who had been to Europe and the embassadors who had come from Europe in 18th and 19th centuries. After Tanzimat (reforms in 1839 amendment of letters had been given point first and then it was abondoned and alphabet replacement attempts began. In later periods serious arguments among the ones in favour and against the transition to Latin alphabet occured. One of the media organs in which these arguments had been appeared was Sebilürreşad. In all these articles acceptance of Latin alphabet was refused and instead the amendment of current letters was required. Some of the articles were taken from the journals of that time and according to the broadcasting policy of the journal occupied a certain place even a little. When the journal had leaned to nationalism and Turanism in its first periods afteryears a critisism began in a distinct manner. The articles related to Latin alphabet belonged to the first periods of the journal. It was seen that especially Turks who had been forced to accept Latin alphabet by Russia in Turkish world were taken place in newspaper columns and it was emphasized that this situation would interrupt the unity within Turkish world. Relections of civilization, printery, economy, colonialism and nationalism in terms of alphabet were also taken place in the journal

Alphabetical co-authorship in the social sciences and humanities: evidence from a comprehensive local database

Energy Technology Data Exchange (ETDEWEB)

Guns, R

2016-07-01

We present an analysis of alphabetical co-authorship in the social sciences and humanities (SSH), based on data from the VABB-SHW, a comprehensive database of SSH research output in Flanders (2000-2013). Using an unbiased estimator of the share of intentional alphabetical co-authorship (IAC), we find that alphabetical co-authorship is more engrained in SSH than in science as a whole. Within the SSH, large differences exist between disciplines. The highest proportions of IAC are found for Literature, Economics & business, and History. Furthermore, alphabetical co-authorship varies with publication type: it occurs most often in books, is less common in articles in journals or in books, and is rare in proceedings papers. The use of alphabetical co-authorship appears to be slowly declining. (Author)

K-12 Local Network (LAN) Design Guide

National Research Council Canada - National Science Library

Horton, Cody

1998-01-01

...) educators preparing to design and implement LANs in K-12 schools and libraries. Data was collected during the implementation of LANs in K-12 schools of the Monterey Peninsula Uniform School District (MPUSD...

Electronics engineer's reference book

CERN Document Server

Turner, L W

1976-01-01

Electronics Engineer's Reference Book, 4th Edition is a reference book for electronic engineers that reviews the knowledge and techniques in electronics engineering and covers topics ranging from basics to materials and components, devices, circuits, measurements, and applications. This edition is comprised of 27 chapters; the first of which presents general information on electronics engineering, including terminology, mathematical equations, mathematical signs and symbols, and Greek alphabet and symbols. Attention then turns to the history of electronics; electromagnetic and nuclear radiatio

3 kW Stirling engine for power and heat production

DEFF Research Database (Denmark)

Thorsen, Jan Eric; Bovin, Jonas Kabell; Carlsen, Henrik

1996-01-01

A new 3 kW Beta-type Stirling engine has been developed. The engine uses natural gas as fuel and is designed for use as a small combined heat and power plant for single family houses. The electrical power is supplied to the grid. The engine is made as a hermetic device, where the crank mechanism...... and the alternator are built into a pressurized crank casing. The engine produces 3 kW of shaft power corresponding to 2.4 kW of electric power. The heat input is 10 kW representing a shaft efficiency of 30% and an electric efficiency of 24%. Helium at 8 MPa mean pressure is used as the working gas. The crank...... for X-heads. A grease-lubricated needle and ball bearings are used in the kinematic crank mechanism. The burner includes an air preheater and a water jacket which makes it possible to utilize nearly all of the heat from the combustion gases. The performance of the engine has been tested as a function...

Biography of louis braille and invention of the braille alphabet.

Science.gov (United States)

Jiménez, Javier; Olea, Jesús; Torres, Jesús; Alonso, Inmaculada; Harder, Dirk; Fischer, Konstanze

2009-01-01

Louis Braille (1809-1852) was born in France. At the age of three, he wounded his right eye with a cobbler's tool while playing in his father's workshop. No medical knowledge could save his eyesight at that time. Louis's left eye became inflamed, apparently due to subsequent sympathetic ophthalmia, and he eventually lost the sight in that eye. At the age of five, Louis Braille was completely blind. He is considered to be the inventor of a writing system by touch that bears his name, the Braille system. This revolutionary system has allowed blind people to access written culture, and it can therefore be considered a major advance in the quality of life for the blind. The immediate precursor of the invention of the Braille system was the alphabet created by Charles Barbier de la Serre (1767-1841) who created a language by touch designed for military and secret use. Louis Braille modified this alphabet into the Braille alphabet, which is practically the same one that is currently used. It required time to be recognized and to be implemented as a reading and writing method for blind people throughout the world. In 1950, UNESCO effectively universalized the Braille alphabet, and in 2005 it recognized Braille system as a "vital language of communication, as legitimate as all other languages in the world."

Amino acid alphabet reduction preserves fold information contained in contact interactions in proteins.

Science.gov (United States)

Solis, Armando D

2015-12-01

To reduce complexity, understand generalized rules of protein folding, and facilitate de novo protein design, the 20-letter amino acid alphabet is commonly reduced to a smaller alphabet by clustering amino acids based on some measure of similarity. In this work, we seek the optimal alphabet that preserves as much of the structural information found in long-range (contact) interactions among amino acids in natively-folded proteins. We employ the Information Maximization Device, based on information theory, to partition the amino acids into well-defined clusters. Numbering from 2 to 19 groups, these optimal clusters of amino acids, while generated automatically, embody well-known properties of amino acids such as hydrophobicity/polarity, charge, size, and aromaticity, and are demonstrated to maintain the discriminative power of long-range interactions with minimal loss of mutual information. Our measurements suggest that reduced alphabets (of less than 10) are able to capture virtually all of the information residing in native contacts and may be sufficient for fold recognition, as demonstrated by extensive threading tests. In an expansive survey of the literature, we observe that alphabets derived from various approaches-including those derived from physicochemical intuition, local structure considerations, and sequence alignments of remote homologs-fare consistently well in preserving contact interaction information, highlighting a convergence in the various factors thought to be relevant to the folding code. Moreover, we find that alphabets commonly used in experimental protein design are nearly optimal and are largely coherent with observations that have arisen in this work. © 2015 Wiley Periodicals, Inc.

African Journals Online: Browse Alphabetically -- letter T

African Journals Online (AJOL)

Items 1 - 19 of 19 ... African Journals Online: Browse Alphabetically -- letter T ... and economic aspects of management and conservation of tropical flora and fauna. ... Les principaux thèmes qui y sont abordés recouvrent les axes de recherche ...

Kichwa or Quichua? Competing Alphabets, Political Histories, and Complicated Reading in Indigenous Languages

Science.gov (United States)

Limerick, Nicholas

2018-01-01

Over the past century, missionary educators, nation-state and academic planners, and literacy development workers have used alphabets for political ends for traditionally marginalized languages, and Native peoples have contested such planning with other alphabet proposals. Yet literacy work now often overlooks that there are multiple alphabets…

Nucleoli in human early erythroblasts (K2, K1, K1/2 cells).

Science.gov (United States)

Smetana, K; Jirásková, I; Klamová, H

2005-01-01

Human early erythroid precursors classified according to the nuclear size were studied to provide information on nucleoli in these cells using simple cytochemical procedures for demonstration of RNA and proteins of silver-stained nucleolar organizers. K2 cells with nuclear diameter larger than 13 microm and K1 cells with nuclear diameter larger than 9 microm corresponding to proerythroblasts and macroblasts (large basophilic erythroblasts) mostly possessed large irregularly shaped nucleoli with multiple fibrillar centres representing "active nucleoli". K1/2 cells with nuclear diameter smaller than 9 microm corresponding to small basophilic erythroblasts were usually characterized by the presence of micronucleoli representing "inactive nucleolar types". On the other hand, a few K1/2 cells contained large nucleoli with multiple fibrillar centres similar to those present in K2 cells and thus appeared as "microproerythroblasts". The nucleolar asynchrony expressed by the presence of large irregularly shaped nucleoli with multiple nucleoli (active nucleoli) and ring-shaped nucleoli (resting nucleoli) in one and the same nucleus of K2 or K1 cells was not exceptional and might reflect a larger resistance of these cells to negative factors influencing the erythropoiesis. The intranucleolar translocation of silver-stained nucleolus organized regions was noted in K2 cells and might indicate the premature aging of these cells without further differentiation. More studies, however, are required in this direction.

Alphabetics: A History of Our Alphabet. A Source Guide for Self-Directed Units. Great Ideas Series. Revised Edition.

Science.gov (United States)

Patton, Sally J.

This teaching resource presents a historical perspective of the alphabet which encompasses a study of major contributions by: (1) "Prehistoric People"; (2) "The Sumerians"; (3) "The Egyptians"; (4) "The Chinese"; (5) "The Greeks"; and (6) "The Romans." Background information, vocabulary study, student activities, a letter history, and a…

Overcoming Constraints of Building Successful Partnerships Incorporating STEM Research Into K-12 Classrooms

Science.gov (United States)

Radencic, S.; McNeal, K. S.; Pierce, D.; Hare, D.

2011-12-01

The Initiating New Science Partnerships in Rural Education (INSPIRE) program at Mississippi State University (MSU), funded by the NSF Graduate STEM Fellows in K-12 Education (GK12) program, focuses on the advancement of Earth and Space science education in K-12 classrooms. INSPIRE is currently in its second year of partnering ten graduate students from the STEM fields of Geosciences, Engineering and Chemistry at MSU with five teachers from local, rural school districts. The five year project serves to increase inquiry and technology experiences in science and math while enhancing graduate student's communication skills as they create interactive lessons linking their STEM research focus to the state and national standards covered in the classrooms. Each graduate student is responsible for the development of two lessons each month of the school year that are then published on the INSPIRE project webpage, www.gk12.msstate.edu, where they are a free resource for any K-12 classroom teacher seeking innovative activities for their classrooms. Many of the participating teachers and graduate students share activities developed with non-participating teachers, expanding INSPIRE's outreach throughout the local community. Numerous challenges were met during the formation of the program as well as throughout the first year in which the project management team worked together to find solutions ensuring that INSPIRE maintained successful partnerships for all involved. Proposed solutions of the following key components were identified by INSPIRE through the development, implementation, and continuous evaluation (internal and external) of the first year of the program as areas that can pose challenges to the construction of strong relationships between STEM research and K-12 classrooms: initializing the partnerships with the K-12 classrooms and STEM graduate fields at the university; maintaining strong partnerships; providing appropriate training and support; developing sound

Involving Practicing Scientists in K-12 Science Teacher Professional Development

Science.gov (United States)

Bertram, K. B.

2011-12-01

The Science Teacher Education Program (STEP) offered a unique framework for creating professional development courses focused on Arctic research from 2006-2009. Under the STEP framework, science, technology, engineering, and math (STEM) training was delivered by teams of practicing Arctic researchers in partnership with master teachers with 20+ years experience teaching STEM content in K-12 classrooms. Courses based on the framework were offered to educators across Alaska. STEP offered in-person summer-intensive institutes and follow-on audio-conferenced field-test courses during the academic year, supplemented by online scientist mentorship for teachers. During STEP courses, teams of scientists offered in-depth STEM content instruction at the graduate level for teachers of all grade levels. STEP graduate-level training culminated in the translation of information and data learned from Arctic scientists into standard-aligned lessons designed for immediate use in K-12 classrooms. This presentation will focus on research that explored the question: To what degree was scientist involvement beneficial to teacher training and to what degree was STEP scientist involvement beneficial to scientist instructors? Data sources reveal consistently high levels of ongoing (4 year) scientist and teacher participation; high STEM content learning outcomes for teachers; high STEM content learning outcomes for students; high ratings of STEP courses by scientists and teachers; and a discussion of the reasons scientists indicate they benefited from STEP involvement. Analyses of open-ended comments by teachers and scientists support and clarify these findings. A grounded theory approach was used to analyze teacher and scientist qualitative feedback. Comments were coded and patterns analyzed in three databases. The vast majority of teacher open-ended comments indicate that STEP involvement improved K-12 STEM classroom instruction, and the vast majority of scientist open-ended comments

Hands-on Summer Camp to Attract K-12 Students to Engineering Fields

Science.gov (United States)

Yilmaz, Muhittin; Ren, Jianhong; Custer, Sheryl; Coleman, Joyce

2010-01-01

This paper explains the organization and execution of a summer engineering outreach camp designed to attract and motivate high school students as well as increase their awareness of various engineering fields. The camp curriculum included hands-on, competitive design-oriented engineering projects from several disciplines: the electrical,…

Alphabetic Phonics: An organization and expansion of orton-gillingham.

Science.gov (United States)

Cox, A R

1985-01-01

Alphabetic Phonics is a sequential language curriculum designed to assure that all students can achieve literacy. This curriculum is a 1980's organization and extension of the Orton-Gillingham-Childs multisensory teaching of the structure of English. Alphabetic Phonics allows 95 percent of the auditory, visual, and kinesthetic learners in a regular classroom to master written English. The curriculum includes modern behavioral, psychological, and educational theories and practice. Developed initially as remediation for dyslexics, Alphabetic Phonics is succeeding both with small groups of severely blocked dyslexics and as prevention in regular classrooms in the primary grades. Administrators, classroom teachers, clinicians, remedial, and resource room specialists, as well as speech and language therapists representing small and large schools (public and private; remedial and accelerated) have traveled to Texas from forty states and six foreign countries during the past ten years to earn graduate credit in one or more of the four month-long Introductory Courses held each year. Teachers report that cultural minority students and those learning English as a second language benefit especially from reading instruction which emphasizes the foundations of English and time-on-task activities to effect mastery. Outreach programs and multimedia tools are being developed and implemented to broaden the programs availability to groups with varied needs.

The Effects of Orthographic Depth on Learning to Read Alphabetic, Syllabic, and Logographic Scripts

Science.gov (United States)

Ellis, Nick C.; Natsume, Miwa; Stavropoulou, Katerina; Hoxhallari, Lorenc; Van Daal, Victor H.P.; Polyzoe, Nicoletta; Tsipa, Maria-Louisa; Petalas, Michalis

2004-01-01

This study investigated the effects of orthographic depth on reading acquisition in alphabetic, syllabic, and logographic scripts. Children between 6 and 15 years old read aloud in transparent syllabic Japanese hiragana, alphabets of increasing orthographic depth (Albanian, Greek, English), and orthographically opaque Japanese kanji ideograms,…

Advanced Energy Design Guide K-12: Next Generation of School Design and Operation

Energy Technology Data Exchange (ETDEWEB)

Torcellini, Paul A [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Pless, Shanti [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

2018-01-01

Driven by energy efficiency advances and renewable energy cost reductions, zero energy buildings are popping up all around the country. Although zero energy represents a bold paradigm shift - from buildings that consume energy to buildings that produce enough energy to meet their energy needs on an annual basis - it isn't a sudden shift. Zero energy buildings are the result of steady, incremental progress by researchers and building professionals working together to improve building energy performance. ASHRAE is taking the lead by publishing - in partnership with the American Institute of Architects (AIA), the Illuminating Engineering Society (IES), the U.S. Green Building Council (USGBC), and the U.S. Department of Energy (DOE) - a new series of advanced energy design guides (AEDGs) focused on zero energy buildings. The recently completed Advanced Energy Design Guide for K-12 School Buildings: Achieving Zero Energy (K-12 ZE AEDG) is the first in this series.

Engineering assessment of 105 K basin monorails

International Nuclear Information System (INIS)

Frier, W.A.

1995-01-01

The engineering assessment of the 105 K Basins monorails was performed to provide the engineering analysis to justify the existing basin north-south monorail capacity. The existing monorails have a capacity of 2400 lbs posted on the north-south monorails. The engineering assessment concluded that the monorail, hanger system, and trolleys all rate for a 2000 lb capacity. Based upon a 2,500 lb trolley load, the monorails, the hanger system, and the double trolley hoist system will rate for 2,500 lbs. The single trolley hoist system for handling the fuel canisters and the trolley systems used in the various transfer areas are limited by manufacturers to 2,000 lbs. Therefore, it is concluded from this engineering assessment that the 2,400 lb capacity posting for the north-south basin monorails is appropriate

Quasi-free K+ photo-production in 12C

International Nuclear Information System (INIS)

Maeda, K.; Yamazaki, H.; Asano, S.; Emura, T.; Endo, I.; Endo, S.; Ito, S.; Itoh, H.; Ifuku, K.; Konno, O.; Koike, M.; Maruyama, K.; Niki, K.; Niwa, K.; Okuno, H.; Sakaguchi, A.; Sasaki, T.; Suda, T.; Sumi, Y.; Takeya, M.; Terasawa, T.; Uchida, H.; Yamashita, H.; Yoshida, K.

1994-01-01

Quasi-free K + photo-production in the 12 C(γ,K + ) reaction has been investigated in a photon energy range of 0.7-1.1GeV. Differential cross sections for the quasi-free process of the 12 C(γ,K + ) reaction have been obtained and they are compared with a calculation of a quasi-free K + photo-production. The effective proton number Z eff =4.2±0.6 obtained from the experiment was in good agreement with a calculation of a semi-classical attenuation model. ((orig.))

Theoretical explanations for preschoolers' lowercase alphabet knowledge.

Science.gov (United States)

Pence Turnbull, Khara L; Bowles, Ryan P; Skibbe, Lori E; Justice, Laura M; Wiggins, Alice K

2010-12-01

Letter knowledge is a key aspect of children's language development, yet relatively little research has aimed to understand the nature of lowercase letter knowledge. We considered 4 hypotheses about children's lowercase letter knowledge simultaneously--uppercase familiarity, uppercase-lowercase similarity, own-name advantage, and frequency in printed English--as well as 3 interactions. Participants were 461 children ranging in age from 3 to 5 years, all of whom attended public preschool programs serving primarily children from low-income homes, who completed a letter naming task. Uppercase familiarity was the strongest predictor of children's lowercase alphabet knowledge; children were more than 16 times more likely to know a lowercase letter if they knew the corresponding uppercase letter. Uppercase-lowercase similarity and frequency in printed English also predicted children's lowercase letter knowledge, as did the interaction between uppercase familiarity and own-name advantage and the interaction between uppercase familiarity and uppercase-lowercase similarity. Findings suggest that transference from uppercase letter knowledge may be a primary mechanism for lowercase letter knowledge and that young children's knowledge of the lowercase alphabet letters is multiply determined.

Laboratory Safety Guide for Arkansas K-12 Schools.

Science.gov (United States)

Arkansas State Dept. of Education, Little Rock.

This document presents laboratory safety rules for Arkansas K-12 schools which were developed by the Arkansas Science Teachers Association (ASTA) and the Arkansas Department of Education (ADE). Contents include: (1) "Laboratory Safety Guide for Arkansas K-12 Schools"; (2) "Safety Considerations"; (3) "Safety Standards for Science Laboratories";…

Females and STEM: Determining the K-12 Experiences that Influenced Women to Pursue STEM Fields

Science.gov (United States)

Petersen, Anne Marie

In the United States, careers in the fields of Science, Technology, Engineering, and Mathematics (STEM) are increasing yet there are not enough trained personnel to meet this demand. In addition, of those that seek to pursue STEM fields in the United States, only 26% are female. In order to increase the number of women seeking STEM based bachelor's degrees, K-12 education must provide a foundation that prepares students for entry into these fields. The purpose of this phenomenological study was to determine the perceived K-12 experiences that influenced females to pursue a STEM field. Twelve college juniors or seniors seeking a degree in Biology, Mathematics, or Physics were interviewed concerning their K-12 experiences. These interviews were analyzed and six themes emerged. Teacher passion and classroom characteristics such as incorporating challenging activities played a significant role in the females' decisions to enter STEM fields. Extra-curricular activities such as volunteer and mentor opportunities and the females' need to benefit others also influenced females in their career choice. Both the formal (within the school) and informal (outside of the traditional classroom) pipeline opportunities that these students encountered helped develop a sense of self-efficacy in science and mathematics; this self-efficacy enabled them to persist in pursuing these career fields. Several participants cited barriers that they encountered in K-12 education, but these barriers were primarily internal as they struggled with overcoming self-imposed obstacles in learning and being competitive in the mathematics and science classrooms. The experiences from these female students can be used by K-12 educators to prepare and encourage current female students to enter STEM occupations.

Are recent cohorts of women with engineering bachelors less likely to stay in engineering?

OpenAIRE

Kahn, Shulamit; Ginther, Donna K.

2015-01-01

Women are an increasing percentage of Bachelors in Engineering (BSEs) graduates – rising from 1% in 1970 to 20% in the 2000s – encouraged by increasing K-12 emphasis on attracting girls to STEM and efforts to incorporate engineering and technology into K-12 curricula. Retention of women in STEM and in engineering in particular has been a concern historically. In this paper, we investigate whether this gap has increased because a larger proportion of females entering engineering find themselve...

Teaching Engineering Habits of Mind in Technology Education

Science.gov (United States)

Loveland, Thomas; Dunn, Derrek

2014-01-01

With a new emphasis on the inclusion of engineering content and practices in technology education, attention has focused on what engineering content should be taught and assessed in technology education. The National Academy of Engineering (2010) proposed three general principles for K-12 engineering education in "Standards for K-12…

Recognition of Arabic Sign Language Alphabet Using Polynomial Classifiers

Directory of Open Access Journals (Sweden)

M. Al-Rousan

2005-08-01

Full Text Available Building an accurate automatic sign language recognition system is of great importance in facilitating efficient communication with deaf people. In this paper, we propose the use of polynomial classifiers as a classification engine for the recognition of Arabic sign language (ArSL alphabet. Polynomial classifiers have several advantages over other classifiers in that they do not require iterative training, and that they are highly computationally scalable with the number of classes. Based on polynomial classifiers, we have built an ArSL system and measured its performance using real ArSL data collected from deaf people. We show that the proposed system provides superior recognition results when compared with previously published results using ANFIS-based classification on the same dataset and feature extraction methodology. The comparison is shown in terms of the number of misclassified test patterns. The reduction in the rate of misclassified patterns was very significant. In particular, we have achieved a 36% reduction of misclassifications on the training data and 57% on the test data.

Keeping Pace with K-12 Online Learning, 2016

Science.gov (United States)

Gemin, Butch; Pape, Larry

2017-01-01

"Keeping Pace with K-12 Online Learning 2016" marks the thirteenth consecutive year Evergreen has published its annual research of the K-12 education online learning market. The thirteen years of researching, writing and publishing this report represents a time of remarkable change. There has been a constant presence that has become the…

Retaining K-12 Online Teachers: A Predictive Model for K-12 Online Teacher Turnover

Science.gov (United States)

Larkin, Ingle M.; Lokey-Vega, Anissa; Brantley-Dias, Laurie

2018-01-01

The purpose of this study was to measure and explore factors influencing K-12 online teachers' turnover intentions, with job satisfaction and organizational commitment serving as moderating variables. Using Fishbein and Ajzen's Theory of Reasoned Action and Planned Behavior (1975), this study was conducted in public, private, charter, for-profit,…

Marshalling Corporate Resources for Public and K-12 Technical Education Outreach and Engagement

Science.gov (United States)

Wynne, James

2011-03-01

In 1988, the Education Task Force of the Business Roundtable recommended that American corporations invest in pre-college education. Prior to that date, corporate investment was targeted at higher education. IBM and other corporations responded by encouraging their employees and their corporate philanthropic organizations to develop programs aimed at enhancing pre-college education. The IBM TJ Watson Research Center initiated a Local Education Outreach program, active for these past 23 years, that marshals the resources of our science-rich institution to enhance STEM education in our local schools. We have broad and deep partnerships between the Research Center and local school districts, including New York City. We have just completed our 19th consecutive year of Family Science Saturdays, which brings 4th and 5th grade children, along with their parents, to our Research Center for hands-on workshops in topics like States of Matter, Polymer Science, Kitchen Chemistry, and Sound and Light. The workshops are staffed by IBM volunteers, assisted by local high school student ``Peer Teachers.'' Since 1990, the IBM Corporation has joined with a coalition of other companies, professional engineering societies, and government agencies to sponsor the annual Engineers Week (EWeek) campaign of technical education outreach, serving as Corporate Chair in 1992, 2001, and 2008. In recent years, we have annually recruited around 5000 IBM volunteers to reach out to more than 200,000 K-12 students in order to increase their awareness and appreciation of technical careers and encourage them to continue their studies of STEM (science, technology, engineering, and mathematics). The speaker, who helped found the APS Forum on Education (FED) and served as FED Councillor for 8 years, will review these and other programs for Public and K-12 Technical Education Outreach and Engagement.

Mastering the International Phonetic Alphabet; Guide and Workbook.

Science.gov (United States)

Decker, Donald M.

The present volume, containing lessons with practice and review exercises, offers a systematic presentation of the symbols of the International Phonetic Alphabet (IPA) most widely used as a simplified means of representing the pronunciation of General American English. The transcription symbols presented are those primarily employed by Kenyon and…

Handbook of mechanical engineering terms

CERN Document Server

Ramalingam, KK

2009-01-01

About the Book: The Handbook of Mechanical Engineering terms contains short, precise definitions of about four thousand terms. These terms have been collected from different sources, edited and grouped under twenty six parts and given alphabetically under each part for easy reference. The book will be a source of guidance and help to the students, staff and practising engineers in understanding and updating the subject matter. Contents: The Handbook of Mechanical Engineering terms contains short, precise definitions of about four thousand terms. These terms have been collected from differ

Letter Frequency Analysis of Lithuanian and Other Languages Using the Latin Alphabet

Directory of Open Access Journals (Sweden)

Gintautas Grigas

2015-12-01

Full Text Available It is important to evaluate specificities of alphabets, particularly the letter frequencies while designing keyboards, analyzing texts, designing games based on alphabets, and doing some text mining. In order to adequately compare lettter frequences of Lithuanian language to other languages in the Internet space, Wikipedia source was selected which content is common to different languages. The method of letter frequency jumps is used. The main attention is paid to the analysis of letter frequencies at the boundary between native letters and foreign letters used in Lithuanian and other languages.

The Coral Reef Alphabet Book for American Samoa.

Science.gov (United States)

Madrigal, Larry G.

This book, produced for the American Samoa Department of Education Marine Enhancement Program, presents underwater color photography of coral reef life in an alphabetical resource. The specimens are described in English, and some are translated into the Samoan language. A picture-matching learning exercise and a glossary of scientific and oceanic…

The protection of the Cyrillic alphabet in telecommunications: Taxation aspects

Directory of Open Access Journals (Sweden)

Marilović Đorđe

2016-01-01

Full Text Available The use of Cyrillic and other specific alphabets is discouraged in some telecommunication services. In this paper; the author focuses on unequal treatment of the Cyrillic alphabet in telecommunications (in SMS messages, which is incompatible with the interests of a multilingual society to cherish its linguistic heritage and diversity. Referring to the Convention on the Protection and Promotion of the Diversity of Cultural Expression (2005, the author suggests introducing measures which would lead to removing the discriminatory pricing of Cyrillic SMS messages; and introducing tax measures which would support mobile network operators and prevent possible market inequalities stemming from introducing these measures. The suggested solution is applicable to any multicultural society facing the same problem; regardless of languages in question.

Living in a Materials World: Materials Science Engineering Professional Development for K-12 Educators

Energy Technology Data Exchange (ETDEWEB)

Anne Seifert; Louis Nadelson

2011-06-01

Advances in materials science are fundamental to technological developments and have broad societal impacs. For example, a cellular phone is composed of a polymer case, liquid crystal displays, LEDs, silicon chips, Ni-Cd batteries, resistors, capacitors, speakers, microphones all of which have required advances in materials science to be compacted into a phone which is typically smaller than a deck of cards. Like many technological developments, cellular phones have become a ubiquitous part of society, and yet most people know little about the materials science associated with their manufacture. The probable condition of constrained knowledge of materials science was the motivation for developing and offering a 20 hour fourday course called 'Living in a Materials World.' In addition, materials science provides a connection between our every day experiences and the work of scientists and engineers. The course was offered as part of a larger K-12 teacher professional development project and was a component of a week-long summer institute designed specifically for upper elementary and middle school teachers which included 20 hour content strands, and 12 hours of plenary sessions, planning, and collaborative sharing. The focus of the institute was on enhancing teacher content knowledge in STEM, their capacity for teaching using inquiry, their comfort and positive attitudes toward teaching STEM, their knowledge of how people learn, and strategies for integrating STEM throughout the curriculum. In addition to the summer institute the participating teachers were provided with a kit of about $300 worth of materials and equipment to use to implement the content they learned in their classrooms. As part of this professional development project the participants were required to design and implement 5 lesson plans with their students this fall and report on the results, as part of the continuing education course associated with the project. 'Living in a

Government Acronyms and Alphabetic Designations Used in DDC.

Science.gov (United States)

Defense Documentation Center, Alexandria, VA.

The compilation consists of a guide to acronyms and alphabetic designations used by the Department of Defense (DOD), federal government and foreign military organizations on documents to designate reports on research monitored by them and cataloged by the Defense Documentation Center (DDC). In all instances the acronyms are those actually used by…

Optimizing Your K-5 Engineering Design Challenge

Science.gov (United States)

Coppola, Matthew Perkins; Merz, Alice H.

2017-01-01

Today, elementary school teachers continue to revisit old lessons and seek out new ones, especially in engineering. Optimization is the process by which an existing product or procedure is revised and refined. Drawn from the authors' experiences working directly with students in grades K-5 and their teachers and preservice teachers, the…

NSF GK-12 Fellows as Mentors for K-12 Teachers Participating in Field Research Experiences

Science.gov (United States)

Ellins, K.; Perry, E.

2005-12-01

The University of Texas Institute for Geophysics (UTIG) recognizes the value of providing educational opportunities to K-12 teachers who play a critical role in shaping the minds of young people who are the future of our science. To that end, UTIG established the "Texas Teachers in the Field" program in 2000 to formalize the participation of K-12 teachers in field programs that included UTIG scientists. In 2002, "Texas Teachers in the Field" evolved through UTIG's involvement in a University of Texas at Austin GK-12 project led by the Environmental Sciences Institute, which enabled UTIG to partner a subset of GK-12 Fellows with teachers participating in geophysical field programs. During the three years of the GK-12 project, UTIG successfully partnered four GK-12 Fellows with five K-12 teachers. The Fellows served as mentors to the teachers, as liaisons between UTIG scientists leading field programs and teachers and their students, and as resources in science, mathematics, and technology instruction. Specifically, Fellows prepared teachers and their students for the field investigations, supervised the design of individual Teacher Research Experience (TRE) projects, and helped teachers to develop standards-aligned curriculum resources related to the field program for use in their own classrooms, as well as broader distribution. Although all but one TRE occurred during the school year, Texas school districts and principals were willing to release teachers to participate because the experience and destinations were so extraordinary (i.e., a land-based program in Tierra del Fuego, Argentina; and research cruises to the Southeast Caribbean Sea and Hess Deep in the Pacific Ocean) and carried opportunities to work with scientists from around the world. This exceptional collaboration of GK-12 Fellows, K-12 teachers and research scientists enriches K-12 student learning and promotes greater enthusiasm for science. The level of mentoring, preparation and follow-up provided

Core Ideas of Engineering and Technology

Science.gov (United States)

Sneider, Cary

2012-01-01

Last month, Rodger Bybee's article, "Scientific and Engineering Practices in K-12 Classrooms," provided an overview of Chapter 3 in "A Framework for K-12 Science Education: Practices, Crosscutting Concepts, and Core Ideas" (NRC 2011). Chapter 3 describes the practices of science and engineering that students are expected to develop during 13 years…

Classifying K-12 Blended Learning

Science.gov (United States)

Staker, Heather; Horn, Michael B.

2012-01-01

The growth of online learning in the K-12 sector is occurring both remotely through virtual schools and on campuses through blended learning. In emerging fields, definitions are important because they create a shared language that enables people to talk about the new phenomena. The blended-learning taxonomy and definitions presented in this paper…

Interstellar Molecules in K-12 Education

Science.gov (United States)

Kuiper, T. B. H.; Hofstadter, M. D.; Levin, S. M.; MacLaren, D.

2006-12-01

The Lewis Center for Educational Research (LCER) and the Jet Propulsion Laboratory (JPL) collaborate in a K-12 educational project in which students conduct observations for several research programs led by radio astronomers. The Goldstone-Apple Valley Radio Telescope (GAVRT) program provides participating teachers with curriculum elements, based on the students' observing experiences, which support national and state academic standards. The current program is based on 2.2-GHz and 8.4-GHz radiometric observations of variable sources. The research programs monitor Jupiter, Uranus, and a selected set of quasars. The telescope is a decommissioned NASA Deep Space Network antenna at Goldstone, California. In the next three years, a second telescope will be added. This telescope will at least operate at the above frequencies as well as 6 GHz and 12 GHz. Possibly, it will operate in a continuous band from 1.2 GHz to 14 GHz. In either case, the telescope will be able to observe at least the 6.6-GHz and 12.2-GHz methanol maser lines. The success of the GAVRT program depends critically on the participation of scientists committed to the research who have the ability and enthusiasm for interacting with K-12 students, typically through teleconferences. The scientists will initially work with the LCER staff to create curriculum elements around their observing program.

K-12 Technology Accessibility: The Message from State Governments

Science.gov (United States)

Shaheen, Natalie L.; Lazar, Jonathan

2018-01-01

This study examined state education technology plans and technology accessibility statutes to attempt to answer the question--is K-12 instructional technology accessibility discussed in state-level technology accessibility statutes and education technology plans across the 50 United States? When a K-12 school district is planning the construction…

Generation of correlated finite alphabet waveforms using gaussian random variables

KAUST Repository

Jardak, Seifallah; Ahmed, Sajid; Alouini, Mohamed-Slim

2014-01-01

, the proposed scheme is general, the main focus of this paper is to generate finite alphabet waveforms for multiple-input multiple-output radar, where correlated waveforms are used to achieve desired beampatterns. © 2014 IEEE.

Sur l’origine de l’écriture libyque. Quelques propositions On the origin of the Libyco-Berber alphabet: A few proposals

Directory of Open Access Journals (Sweden)

Dominique Casajus

2013-06-01

Full Text Available Le présent article propose quelques hypothèses sur l’origine des alphabets dits libyques. Attestés par plus d’un millier d’inscriptions recueillies dans toute l’Afrique du Nord, depuis la Libye jusqu’aux îles Canaries, ces alphabets sont selon toute vraisemblance les ancêtres des alphabets touaregs actuels. La seule inscription qui ait pu être datée avec un degré raisonnable de certitude est une bilingue libyco-punique, mise au jour sur le site de Dougga (Tunisie, qui daterait de 139 avant J.-C. Il semble que les alphabets libyques existaient déjà alors depuis plusieurs siècles. Leurs créateurs ont emprunté quelques lettres (au moins quatre aux alphabets phénico-puniques. Pour composer les autres lettres, ils semblent avoir eu recours à des procédés géométriques simples qu’on essaie ici de reconstituer.A few hypotheses about the origin of the so-called “Libyan” alphabets are presented. Attested in more than a thousand inscriptions from Libya to the Canary Islands in northern Africa, these alphabets are probably the forebears of the current ones used by the Tuareg. The only inscription that has been dated (139 BCE with a reasonable degree of certainty is bilingual, Libyco-Punic, from Dougga in Tunisia. The “Libyan” alphabets apparently already existed, several centuries earlier. Their creators borrowed a few — at least four — letters from the Phoenician/Punic alphabets; and apparently used simple geometric procedures, which are reconstituted herein, for the other letters.

An Overview of the Literature: Research in P-12 Engineering Education

Science.gov (United States)

Mendoza Díaz, Noemi V.; Cox, Monica F.

2012-01-01

This paper presents an extensive overview of preschool to 12th grade (P-12) engineering education literature published between 2001 and 2011. Searches were conducted through education and engineering library engines and databases as well as queries in established publications in engineering education. More than 50 publications were found,…

Final report on 9 kW Stirling Engine for biogas and natural gas

DEFF Research Database (Denmark)

Carlsen, Henrik; Bovin, Jonas Kabell

2001-01-01

The need for a simple and robust engine for natural gas and low quality gas has resulted in the design of a single cylinder, hermetic Stirling engine, which has an electric power output of 9 kW. Two engines have been built. One engine is intended for natural gas as fuel and the other is intended...... eliminates guiding forces on the pistons and the need for X-heads. Grease lubricated needle and ball bearings are used in the kinematic crank mechanism in order to avoid oil penetrating into the cylinder volumes. Working gas is Helium at 8 MPa mean pressure. The engine produce up to 11 kW of shaft power...... corresponding to approximately 10 kW of electric power. The design target was an efficiency of 26 % based on lower heat content of the gas to electricity, but only 24% were obtained. The decrease of efficiency is caused by inhomogeneous capacity flows in the air preheater and insufficient insulation...

Construction of non-viral vector (mPEG5k-PCL1.2k)1.4-g-PEI10k and its gene delivery efficacy in vitro

OpenAIRE

Wei HUANG; Ming LV; Zhong-gao GAO; Ming-ji JIN; Fei-fei YANG; Yu-li WANG

2011-01-01

Objective To construct(mPEG5k-PCL1.2k)1.4-g-PEI10k,a copolymer designed as delivery vector for non-viral gene therapy,and explore its cytotoxicity and efficacy in delivery of plasmid DNA(pDNA).Methods The copolymer,mPEG5k-PCL1.2k-OH,was prepared by ring-opening polymerization and then followed by a conversion of hydroxyl terminal(-OH) into N-hydroxysuccinimide(NHS) to prepare mPEG5k-PCL1.2k-NHS.One of the branches,PEI10k,was then reacted with mPEG5k-PCL1.2k-NHS to synthesize a ternary copolym...

Genesis, visual attributes and contemporary communication features of the alphabet

Directory of Open Access Journals (Sweden)

Filip Cvitić

2014-10-01

Full Text Available Throughout 5,000 years of human literacy, the alphabet system has developed from pictograms and ideograms to the contemporary system of Latin letters. The simplification of primary pictograms and their transformation to ideograms followed the major goal of written communication – to transmit thoughts and ideas. Besides, written communication has enabled preservation of knowledge, and that has generated the expansion of information and its availability today. The high speed of gathering written information, as well as its superabundance, calls for rethinking of semiotic features of Latin letters as the basic units of written communication in the Western world, especially in terms of marketing communication and its effectiveness. The written expression is the major tool of branding and getting closer to target market segments. Social development influences the development of communication, which is visible through numerous brands and signs, i.e. symbols that make products and companies recognizable in the market. The distinct sign forms of the alphabet are used to suggest the story of a brand, product or service. A constituent element of its comprehension is conscious or unconscious knowledge drawn from different sources in the environment. The history of human literacy, the development of each particular letter, the communication rules of the contemporary marketplace, the impact of brands and information superabundance make up the basis for further research into communication features of the alphabet, semantics of written forms and their redefinition in the context of effective marketing communication.

Infusing Engineering Concepts: Teaching Engineering Design

Science.gov (United States)

Daugherty, Jenny

2012-01-01

Engineering has gained considerable traction in many K-12 schools. However, there are several obstacles or challenges to an effective approach that leads to student learning. Questions such as where engineering best fits in the curriculum; how to include it authentically and appropriately; toward what educational end; and how best to prepare…

Harnessing Technology to Improve K-12 Education. Discussion Paper 2012-05

Science.gov (United States)

Chatterji, Aaron; Jones, Benjamin

2012-01-01

Technological progress has consistently driven remarkable advances in the U.S. economy, yet K-12 education sees little technological change compared to other sectors, even as U.S. K-12 students increasingly lag behind students in other nations. This proposal considers how we can take a signature American strength--innovation--and apply it to K-12…

Using K-Nearest Neighbor in Optical Character Recognition

Directory of Open Access Journals (Sweden)

Veronica Ong

2016-03-01

Full Text Available The growth in computer vision technology has aided society with various kinds of tasks. One of these tasks is the ability of recognizing text contained in an image, or usually referred to as Optical Character Recognition (OCR. There are many kinds of algorithms that can be implemented into an OCR. The K-Nearest Neighbor is one such algorithm. This research aims to find out the process behind the OCR mechanism by using K-Nearest Neighbor algorithm; one of the most influential machine learning algorithms. It also aims to find out how precise the algorithm is in an OCR program. To do that, a simple OCR program to classify alphabets of capital letters is made to produce and compare real results. The result of this research yielded a maximum of 76.9% accuracy with 200 training samples per alphabet. A set of reasons are also given as to why the program is able to reach said level of accuracy.

Assessing the Impact of a Statewide STEM Investment on K-12, Higher Education, and Business/Community STEM Awareness over Time

Science.gov (United States)

Sondergeld, Toni A.; Johnson, Carla C.; Walten, Janet B.

2016-01-01

Despite monetary and educational investments in science, technology, engineering, and mathematics (STEM) being at record high levels, little attention has been devoted to generating a common understanding of STEM. In addition, working with business, K-12 schools, and/or institutions of higher education to establish a grassroots effort to help…

Rakesh K. Kapania named Norris and Laura Mitchell Professor of Aerospace Engineering

OpenAIRE

Crumbley, Liz

2008-01-01

Rakesh K. Kapania, a professor in the Department of Aerospace and Ocean Engineering in the College of Engineering at Virginia Tech, was appointed the Norris and Laura Mitchell Professor of Aerospace Engineering by the Virginia Tech Board of Visitors during the board's quarterly meeting March 31.

The Metamorphosis by K. (12)

CERN Multimedia

CERN Bulletin

2012-01-01

In the last issue of the Bulletin we reported on the first run of the new NA62 experiment. In this issue, we go behind the scenes to take a look at the production of the experiment's new kaon beam.   The start of the K12 beam line as seen during the installation of the shielding. 10-2, 10-3, 10-4, 10-5, 10-6 mbar… send in the protons! Since Thursday 1 November, the P42 beam line of the SPS has once again been sending protons to the beryllium target to produce the K12 kaon beam line eagerly awaited by the NA62 collaboration. This was no trivial matter! The first step was to clear the decks by dismantling the entire H10 beam line and NA60 experiment, as well as most of the NA48 experiment - representing some 1000 tonnes of equipment in total! Next came the complete renovation of the infrastructure, which dated back to 1979. The operation called on the expertise of virtually all branches of the EN and GS departments, as well as the Radiation Protection group: from ...

Engineering and erection of a 300kW high-flux solar simulator

Science.gov (United States)

Wieghardt, Kai; Laaber, Dmitrij; Hilger, Patrick; Dohmen, Volkmar; Funken, Karl-Heinz; Hoffschmidt, Bernhard

2017-06-01

German Aerospace Center (DLR) is currently constructing a new high-flux solar simulator synlight which shall be commissioned in late 2016. The new facility will provide three separately operated experimental spaces with expected radiant powers of about 300kW / 240kW / 240kW respectively. synlight was presented to the public for the first time at SolarPACES 2015 [1]. Its engineering and erection is running according to plan. The current presentation reports about the engineering and the ongoing erection of the novel facility, and gives an outlook on its new level of possibilities for solar testing and qualification.

Numerically Optimized Uniformly Most Powerful Alphabets for Hierarchical-Decode-and-Forward Two-Way Relaying

Directory of Open Access Journals (Sweden)

M. Hekrdla

2011-01-01

Full Text Available We address the issue of the parametric performance of the Hierarchical-Decode-and-Forward (HDF strategy in a wireless 2-way relay channel. Promising HDF, representing the concept of wireless network coding, performs well with a pre-coding strategy that requires Channel State Information (CSI on the transceiver side. Assuming a practical case when CSI is available only on the receiver side and the channel conditions do not allow adaptive strategies, the parametrization causes significant HDF performance degradation for some modulation alphabets. Alphabets that are robust to the parametrization (denoted Uniformly Most Powerful (UMP have already been proposed restricting on the class of non-linear multi-dimensional frequency modulations. In this work, we focus on the general design of unrestricted UMP alphabets. We formulate an optimization problem which is solved by standard non-linear convex constrained optimization algorithms, particularly by Nelder-Mead global optimization search, which is further refined by the local interior-pointsmethod.

Examination of engineering design teacher self-efficacy and knowledge base in secondary technology education and engineering-related courses

Science.gov (United States)

Vessel, Kanika Nicole

2011-12-01

There is an increasing demand for individuals with engineering education and skills of varying fields in everyday life. With the proper education students of high-needs schools can help meet the demand for a highly skilled and educated workforce. Researchers have assumed the supply and demand has not been met within the engineering workforce as a result of students' collegiate educational experiences, which are impacted by experiences in K-12 education. Although factors outside of the classroom contribute to the inability of universities to meet the increasing demand for the engineering workforce, most noted by researchers is the academic unpreparedness of freshman engineering students. The unpreparedness of entering freshman engineering students is a result of K-12 classroom experiences. This draws attention not only to the quality and competence of teachers present in the K-12 classroom, but the type of engineering instruction these students are receiving. This paper was an effort to systematically address one of the more direct and immediate factors impacting freshman engineering candidates, the quality of secondary engineering educators. Engineers develop new ideas using the engineering design process, which is taught at the collegiate level, and has been argued to be the best approach to teach technological literacy to all K-12 students. However, it is of importance to investigate whether technology educators have the knowledge and understanding of engineering design, how to transfer that knowledge in the classroom to students through instructional strategies, and their perception of their ability to do that. Therefore, the purpose of this study is to show the need for examining the degree to which technology and non-technology educators are implementing elements of engineering design in the curriculum.

A reduced amino acid alphabet for understanding and designing protein adaptation to mutation.

Science.gov (United States)

Etchebest, C; Benros, C; Bornot, A; Camproux, A-C; de Brevern, A G

2007-11-01

Protein sequence world is considerably larger than structure world. In consequence, numerous non-related sequences may adopt similar 3D folds and different kinds of amino acids may thus be found in similar 3D structures. By grouping together the 20 amino acids into a smaller number of representative residues with similar features, sequence world simplification may be achieved. This clustering hence defines a reduced amino acid alphabet (reduced AAA). Numerous works have shown that protein 3D structures are composed of a limited number of building blocks, defining a structural alphabet. We previously identified such an alphabet composed of 16 representative structural motifs (5-residues length) called Protein Blocks (PBs). This alphabet permits to translate the structure (3D) in sequence of PBs (1D). Based on these two concepts, reduced AAA and PBs, we analyzed the distributions of the different kinds of amino acids and their equivalences in the structural context. Different reduced sets were considered. Recurrent amino acid associations were found in all the local structures while other were specific of some local structures (PBs) (e.g Cysteine, Histidine, Threonine and Serine for the alpha-helix Ncap). Some similar associations are found in other reduced AAAs, e.g Ile with Val, or hydrophobic aromatic residues Trp with Phe and Tyr. We put into evidence interesting alternative associations. This highlights the dependence on the information considered (sequence or structure). This approach, equivalent to a substitution matrix, could be useful for designing protein sequence with different features (for instance adaptation to environment) while preserving mainly the 3D fold.

INCREASING ACHIEVEMENT AND HIGHER-EDUCATION REPRESENTATION OF UNDER-REPRESENTED GROUPS IN SCIENCE, TECHNOLOGY, ENGINEERING, AND MATHEMATICS FIELDS: A REVIEW OF CURRENT K-12 INTERVENTION PROGRAMS.

Science.gov (United States)

Valla, Jeffrey M; Williams, Wendy M

2012-01-01

The under-representation of women and ethnic minorities in Science, Technology, Engineering, and Mathematics (STEM) education and professions has resulted in a loss of human capital for the US scientific workforce and spurred the development of myriad STEM educational intervention programs. Increased allocation of resources to such programs begs for a critical, prescriptive, evidence-based review that will enable researchers to develop optimal interventions and administrators to maximize investments. We begin by providing a theoretical backdrop for K-12 STEM programs by reviewing current data on under-representation and developmental research describing individual-level social factors undergirding these data. Next, we review prototypical designs of these programs, highlighting specific programs in the literature as examples of program structures and components currently in use. We then evaluate these interventions in terms of overall effectiveness, as a function of how well they address age-, ethnicity-, or gender-specific factors, suggesting improvements in program design based on these critiques. Finally, program evaluation methods are briefly reviewed and discussed in terms of how their empirical soundness can either enable or limit our ability to delineate effective program components. "Now more than ever, the nation's changing demographics demand that we include all of our citizens in science and engineering education and careers. For the U.S. to benefit from the diverse talents of all its citizens, we must grow the pipeline of qualified, underrepresented minority engineers and scientists to fill positions in industry and academia."-Irving P. McPhail..

Development of Toyota new 1GZ-FE engine; Shingata V12 gasoline engine no kaihatsu

Energy Technology Data Exchange (ETDEWEB)

Kawamura, H; Asahi, T; Goto, M; Endo, K; Terada, M [Toyota Motor Corp., Aichi (Japan)

1997-10-01

The first V-12 cylinder engine for passenger car in Japan, the 1GZ-FE, which is the status of high luxury vehicles has been developed. In order to proceed the merit of V-12 cylinder engine, Intelligent Variable Valve Timing (VVT-i) system, Slant squish combustion chamber, Iridium pole spark plug and Intelligent electronic throttle control system were introduced. Through these features this new 1GZ-FE has achieved an overwhelming smoothness and quietness and yet highest torque among the same displacement engine at low and medium engine speed. Additionally the 1GZ-FE achieved good fuel economy and high reliability which exceed any other competitors. 14 refs., 4 figs.

SAFARI engineering model 50 mK cooler

Science.gov (United States)

Duband, L.; Duval, J. M.; Luchier, N.

2014-11-01

SAFARI is an infrared instrument developed by a European based consortium to be flown in SPICA, a Japanese led mission. The SAFARI detectors are transition edge sensors (TES) and require temperatures down to 50 mK for their operation. For that purpose we have developed a hybrid architecture based on the combination of a 300 mK sorption stage and a small adiabatic demagnetization stage. An engineering model has been designed to provide net heat lifts of 0.4 and 14 μW respectively at 50 and 300 mK, with an overall cycle duration of 48 h and a duty cycle objective of over 75%. The cooler is self-contained, fits in a volume of 156 × 312 × 182 mm and is expected to weigh 5.1 kg. It has been designed to withstand static loads of 120 g and a random vibration level of 21 g RMS.

K-12 Mathematics and the Web

Science.gov (United States)

Glazer, Evan

2005-01-01

The Web offers numerous learning resources and opportunities for K-12 mathematics education. This paper discusses those resources and opportunities. Discussion includes (a) asynchronous and synchronous communication tools, (b) the use of data sets to make connections between mathematics concepts and real-world applications, and (c) interactive…

A Chemical Alphabet for Macromolecular Communications.

Science.gov (United States)

Giannoukos, Stamatios; McGuiness, Daniel Tunç; Marshall, Alan; Smith, Jeremy; Taylor, Stephen

2018-06-08

Molecular communications in macroscale environments is an emerging field of study driven by the intriguing prospect of sending coded information over olfactory networks. For the first time, this article reports two signal modulation techniques (on-off keying-OOK, and concentration shift keying-CSK) which have been used to encode and transmit digital information using odors over distances of 1-4 m. Molecular transmission of digital data was experimentally investigated for the letter "r" with a binary value of 01110010 (ASCII) for a gas stream network channel (up to 4 m) using mass spectrometry (MS) as the main detection-decoding system. The generation and modulation of the chemical signals was achieved using an automated odor emitter (OE) which is based on the controlled evaporation of a chemical analyte and its diffusion into a carrier gas stream. The chemical signals produced propagate within a confined channel to reach the demodulator-MS. Experiments were undertaken for a range of volatile organic compounds (VOCs) with different diffusion coefficient values in air at ambient conditions. Representative compounds investigated include acetone, cyclopentane, and n-hexane. For the first time, the binary code ASCII (American Standard Code for Information Interchange) is combined with chemical signaling to generate a molecular representation of the English alphabet. Transmission experiments of fixed-width molecular signals corresponding to letters of the alphabet over varying distances are shown. A binary message corresponding to the word "ion" was synthesized using chemical signals and transmitted within a physical channel over a distance of 2 m.

Performance of the 1 kW thermoelectric generator for diesel engines

International Nuclear Information System (INIS)

Bass, J.C.; Elsner, N.B.; Leavitt, F.A.

1994-01-01

Hi-Z Technology, Inc. (Hi-Z) has been developing a 1 kW thermoelectric generator for class eight Diesel truck engines under U.S. Department of Energy and California Energy Commission funding since 1992. The purpose of this generator is to replace the currently used shaft-driven alternator by converting part of the waste heat in the engine's exhaust directly to electricity. The preliminary design of this generator was reported at the 1992 meeting of the XI-ICT in Arlington, Texas. This paper will report on the final mechanical, thermal and thermoelectric design of this generator. The generator uses seventy-two of Hi-Z's 13 Watt bismuth-telluride thermoelectric modules for energy conversion. The number of modules and their arrangement has remained constant through the program. The 1 kW generator was tested on several engines during the development process. Many of the design features were changed during this development as more information was obtained. We have only recently reached our design goal of 1 kW output. The output parameters of the generator are reported. copyright 1995 American Institute of Physics

Characteristics of the process K+p→K+anti ppp at 12 GeV/c

International Nuclear Information System (INIS)

Armstrong, T.A.; Frame, D.; Hughes, I.S.; Kumar, B.R.; Lewis, G.M.; Macallister, J.B.; Stewart, D.T.; Turnbull, R.M.

1979-01-01

Data are presented on the reaction K + p→K + anti ppp at 12 GeV/c from an experiment using the OMEGA spectrometer at CERN. A clear Λ(1520) signal is observed in the process K + p→anti Λ(1520)pp and angular distributions and correlations are presented for this process. The angular distributions for the reaction in which anti Λ(1520) is not produced show an appreciable backward K + peak. (Auth.)

A K Shukla

Indian Academy of Sciences (India)

Cars Beyond Otto's Internal Combustion Engines · A K Shukla · More Details Fulltext PDF. Volume 11 Issue 7 July 2006 pp 42-50 General Article. Turning Sunlight into Electricity - Inorganic Solar Cells and Beyond · A K Shukla · More Details Fulltext PDF. Volume 15 Issue 12 December 2010 pp 1068-1072 General Article.

Updating and test on 12 kA HTSCL for Russia JINR

International Nuclear Information System (INIS)

Zhou, Tingzhi; Ding, K; Liu, C; Xu, C; Feng, H; Wu, H; Liu, X; Song, Y

2014-01-01

The Joint Institute for Nuclear Research (JINR) started manufacture and test of superconducting magnets for the new accelerator complex Nuclotron-based Ion Collider fAcility (NICA). A pair of current leads rated 12 kA was developed for cold testing of the magnets in 2012. The operation of the facility needs ∼350 leads rated from 100 A to 12 kA to convey current for the magnets. After the test of the pair of 12 kA leads in JINR a contract of supplying 3 pairs of 12 kA high temperature superconducting current leads (HTSCLs) were signed to ASIPP this year. In this paper the design updating and test of the current leads are introduced.

[The alphabet of nature and the alphabet of culture in the eighteenth century. botany, diplomatics, and ethno-linguistics according to Carl von Linné, Johann Christoph Gatterer, and Christian Wilhelm Büttner : Botany, Diplomatics, and ethno-linguistics according to Carl von Linné, Johann Christoph Gatterer, and Christian Wilhelm Büttner].

Science.gov (United States)

Gierl, Martin

2010-01-01

In the middle of the eighteenth century, Carl von Linné, Johann Christoph Gatterer, and Christian Wilhelm Büttner attempted to realize the old idea of deciphering the alphabet of the world, which Francis Bacon had raised as a general postulate of science. This article describes these attempts and their interrelations. Linné used the model of the alphabet to classify plants according to the characters of this fruiting body. Gatterer, one of the leading German historians during the Enlightenment, adopted the botanical method of classification by genus and species to classify the history of scripts. He used the forms of the alphabetic characters to measure the age of manuscripts and to map the process of history as a genealogy of culture. Gatterer collaborated closely with Büttner, the first Göttingen professor of natural history. Büttner constructed a general alphabet of languages which connected the phonetics of language with the historically known alphabets. Early on, diplomatics and ethnography combined the natural order of natural history and the cultural order of the alphabet with the attempt to register development and to document development by the evolution of forms. Based on the shared model of the alphabet and on the common necessity to classify their empirical material, natural history and the description of culture were related attempts in the middle of the eighteenth century to comprehend the alphabetically organized nature and a naturally ordered culture.

A Selective Bibliography of Commercial Radio and Television Engineering.

Science.gov (United States)

Losee, Robert M., Jr.

A selective bibliography of materials published in the area of commercial radio and television engineering covers relevant areas as well as some described as peripheral including lighting, management, and microwave transmission theory. Reference materials are grouped alphabetically by case studies, circuits, current awareness services,…

Exploring Complex Engineering Learning Over Time with Epistemic Network Analysis

OpenAIRE

Svarovsky, Gina Navoa

2011-01-01

Recently, K-12 engineering education has received increased attention as a pathway to building stronger foundations in math andscience and introducing young people to the profession. However, the National Academy of Engineering found that many K-12engineering programs focus heavily on engineering design and science and math learning while minimizing the development ofengineering habits of mind. This narrowly-focused engineering activity can leave young people – and in particular, girls – with...

Parents' Goals for and Perceptions of Alphabet Books

Science.gov (United States)

Nowak, Sarah N.; Evans, Mary Ann

2013-01-01

This study examined parents' goals for reading ABC books with their children and their perceptions of page features. Factor analysis of a questionnaire answered by 225 parents of junior and senior kindergarten students revealed four goals for reading alphabet books. In order of importance as rated by parents the goals were: Learning to Read,…

Examining the Personal Nature of the K-14 Engineering Pipeline for Young Women

Science.gov (United States)

Gurski, Jennifer Sue

This mixed-methods study examined young women's perceptions of their K-14 STEM pipeline experiences and their resulting choice to enter and persist in an engineering major. Despite the increase of women in the STEM workforce, women remain underrepresented among engineering majors (Beasley & Fischer, 2012; Heilbronner, 2012; Neihart & Teo, 2013). Few studies exist that utilize a retrospective approach to understand how the culmination of young women's K-14 experiences have influenced their formation of individually held perceptions that lead to engineering persistence. It is this study's aim to utilize a mixed-methods approach to answer the following research question: How do young women's perceptions of their K-14 STEM experiences influence their decision to enroll and persist in an engineering major? These perceptions are explored through an ethnographic approach focusing on young women enrolled in engineering programs during their junior and senior years of study at a small private liberal arts university with eight engineering majors. The mixed-methods approach follows a sequential design method (Creswell, 2013) and utilizes questions in a quantitative Likert-type survey from the Academic Pathways for People Learning Engineering (APPLES) survey (Eris, Chachra, Chen, Sheppard, & Ludlow, 2010) and the Motivated Strategy Learning Questionnaire (MSLQ) (Pintrich, Smith, Garcia, & McKeachie, 1991). The quantitative study results will lead to the development of open-ended, structured questions for conducting a qualitative focus group. Anonymity of all participants is maintained. Keywords: STEM, young women, perceptions, pipeline, intervention, underrepresentation, engineering, persistence, retrospective, self-efficacy.

Generation of correlated finite alphabet waveforms using gaussian random variables

KAUST Repository

Ahmed, Sajid

2016-01-13

Various examples of methods and systems are provided for generation of correlated finite alphabet waveforms using Gaussian random variables in, e.g., radar and communication applications. In one example, a method includes mapping an input signal comprising Gaussian random variables (RVs) onto finite-alphabet non-constant-envelope (FANCE) symbols using a predetermined mapping function, and transmitting FANCE waveforms through a uniform linear array of antenna elements to obtain a corresponding beampattern. The FANCE waveforms can be based upon the mapping of the Gaussian RVs onto the FANCE symbols. In another example, a system includes a memory unit that can store a plurality of digital bit streams corresponding to FANCE symbols and a front end unit that can transmit FANCE waveforms through a uniform linear array of antenna elements to obtain a corresponding beampattern. The system can include a processing unit that can encode the input signal and/or determine the mapping function.

Generation of correlated finite alphabet waveforms using gaussian random variables

KAUST Repository

Ahmed, Sajid; Alouini, Mohamed-Slim; Jardak, Seifallah

2016-01-01

Various examples of methods and systems are provided for generation of correlated finite alphabet waveforms using Gaussian random variables in, e.g., radar and communication applications. In one example, a method includes mapping an input signal comprising Gaussian random variables (RVs) onto finite-alphabet non-constant-envelope (FANCE) symbols using a predetermined mapping function, and transmitting FANCE waveforms through a uniform linear array of antenna elements to obtain a corresponding beampattern. The FANCE waveforms can be based upon the mapping of the Gaussian RVs onto the FANCE symbols. In another example, a system includes a memory unit that can store a plurality of digital bit streams corresponding to FANCE symbols and a front end unit that can transmit FANCE waveforms through a uniform linear array of antenna elements to obtain a corresponding beampattern. The system can include a processing unit that can encode the input signal and/or determine the mapping function.

Is Chinese Special? Four Aspects of Chinese Literacy Acquisition That Might Distinguish Learning Chinese from Learning Alphabetic Orthographies

Science.gov (United States)

McBride, Catherine Alexandra

2016-01-01

Some aspects of Chinese literacy development do not conform to patterns of literacy development in alphabetic orthographies. Four are highlighted here. First, semantic radicals are one aspect of Chinese characters that have no analogy to alphabetic orthographies. Second, the unreliability of phonological cues in Chinese along with the fact that…

Control of 12-Cylinder Camless Engine with Neural Networks

Directory of Open Access Journals (Sweden)

Ashhab Moh’d Sami

2017-01-01

Full Text Available The 12-cyliner camless engine breathing process is modeled with artificial neural networks (ANN’s. The inputs to the net are the intake valve lift (IVL and intake valve closing timing (IVC whereas the output of the net is the cylinder air charge (CAC. The ANN is trained with data collected from an engine simulation model which is based on thermodynamics principles and calibrated against real engine data. A method for adapting single-output feed-forward neural networks is proposed and applied to the camless engine ANN model. As a consequence the overall 12-cyliner camless engine feedback controller is upgraded and the necessary changes are implemented in order to contain the adaptive neural network with the objective of tracking the cylinder air charge (driver’s torque demand while minimizing the pumping losses (increasing engine efficiency. All the needed measurements are extracted only from the two conventional and inexpensive sensors, namely, the mass air flow through the throttle body (MAF and the intake manifold absolute pressure (MAP sensors. The feedback controller’s capability is demonstrated through computer simulation.

Logic-Symbolic and Alphabetization

Directory of Open Access Journals (Sweden)

Dair Aily Franco de Camargo

2007-10-01

Full Text Available The present article tries to recoup the ideas and the proposal of H. Furth (1973, pointing it as another option to try to work with the children’s difficulties in the alphabetization process. The author considers the substitution of “schools of the language” for “schools of the thought”, that is, to substitute the option of the teacher in the reading-writing education, in its traditional form, of how to transform graphical signals into sonorous and vice-versa, for that one of the thought consolidation, feeding the intellect in development of the child by exercises of “symbolic logic”. For theoretical basing, we still present some aspects of the psychogenetic theory, as well as other works carried through more recently on the subject, that even so “transvestite” (disguised with new clothing, still find their beddings in the J. Piaget’s basis.

dNTPs :  the alphabet of life

OpenAIRE

Kumar, Dinesh

2010-01-01

From microscopic bacteria to the giant whale, every single living organism on Earth uses the same language of life: DNA. Deoxyribonucleoside triphosphates––dNTPs (dATP, dTTP, dGTP, and dCTP)––are the building blocks of DNA and are therefore the “alphabet of life”. A balanced supply of dNTPs is essential for integral DNA transactions such as faithful genome duplication and repair. The enzyme ribonucleotide reductase (RNR) not only synthesizes all four dNTPs but also primarily maintains the cru...

Digital Learning in California's K-12 Schools. Just the Facts

Science.gov (United States)

Gao, Niu

2015-01-01

This fact page briefly discusses the following facts on digital learning in California's K-12: (1) As California implements new tests in its K-12 schools, technology infrastructure is a key concern; (2) Many districts are confident that they had enough bandwidth for online field tests; (3) Digital learning will require significantly greater…

Inquiry by Engineering Design: Applying the Sixth "E"

Science.gov (United States)

Brand, Brenda; Kasarda, Mary; Williams, Christopher Bryant

2017-01-01

As the emphasis on STEM education increases, the "E" (engineering) in the acronym is gaining more attention in K-12 education. K-12 educators are urged to develop new and creative strategies for engaging youth in science and engineering activities that encourage them to be inventors and not just consumers. The Inquiry By Engineering…

Systematic study of K+ and K- charge exchange at 8.36 and 12.8 GeV/c

International Nuclear Information System (INIS)

Gilchriese, M.G.D.

1977-08-01

The results of a wire chamber spectrometer experiment at the Stanford Linear Accelerator Center to study kaon charge exchange reactions are reported. The salient experimental features include good relative normalization between the K + and K - charge exchange reactions and a large increase, with respect to previous experiments, in the number of events obtained for K + n charge exchange at the higher energy. Approximately 1500 events at 12.8 GeV/c and 250 events at 8.36 GeV/c were obtained for each of the reactions K + n → K 0 p, K - p → anti K 0 n, K + p → K 0 Δ 2+ and K - n → anti K 0 Δ - . The results of the experiment show that the K + charge exchange cross sections are larger than the K - cross sections at both energies. In particular it is found that sigma/sub tot/ (K + n → K 0 p)/sigma/sub tot/ (K - p → anti K 0 n) is 1.37 +- 0.22 at 8.36 GeV/c and 1.38 +- 0.09 at 12.8 GeV/c. The ratio of these two reactions is also consistent with no momentum transfer dependence at either beam energy. Similarly it was determined that sigma/sub tot/ (K + p → K 0 Δ 2+ )/sigma/sub tot/ (K - n → anti K 0 Δ - ) is 1.05 +- 0.16 at 8.36 GeV/c and 1.56 +- 0.08 at 12.8 GeV/c. The ratio of these two reactions is also consistent with momentum transfer independence for both beam energies. These results are in clear conflict with the predictions of exchange degenerate Regge pole models

Copyright Updates for K-12 Librarians

Science.gov (United States)

Johnson, Wendell G.

2016-01-01

Copyright concerns continue to bedevil K-12 librarians, who are often called upon to act as the copyright officers in public schools. This article describes recent copyright developments of concern to these librarians in three areas: a recent court case involving a university library, pending legislation supported by ALA, and a regulatory update.…

The collision cross sections for excitation energy transfer in Rb*(5P3/2)+K(4S1/2)→Rb(5S1/2)+K*(4PJ) processes

International Nuclear Information System (INIS)

Horvatic, V.; Vadla, C.; Movre, M.

1993-01-01

The collisional excitation transfer for the processes Rb * (5P 3/2 ) + K(4S 1/2 ) → Rb(5S 1/2 ) + K * (4P J ), J = 1/2, 3/2, was investigated using two-photon laser excitation techniques with a thermionic heat-pipe diode as a detector. The population densities of the K 4P J levels induced by collisions with excited Rb atoms as well as those produced by direct laser excitation of the potassium atoms were probed through the measurement of the thermionic signals generated due to the ionization of the potassium atoms emerging from the K(4P J ) → K(7S 1/2 ) excitation channel. (orig./WL)

Sample environment for neutron scattering measurements of internal stresses in engineering materials in the temperature range of 6 K to 300 K.

Science.gov (United States)

Kirichek, O; Timms, J D; Kelleher, J F; Down, R B E; Offer, C D; Kabra, S; Zhang, S Y

2017-02-01

Internal stresses in materials have a considerable effect on material properties including strength, fracture toughness, and fatigue resistance. The ENGIN-X beamline is an engineering science facility at ISIS optimized for the measurement of strain and stress using the atomic lattice planes as a strain gauge. Nowadays, the rapidly rising interest in the mechanical properties of engineering materials at low temperatures has been stimulated by the dynamic development of the cryogenic industry and the advanced applications of the superconductor technology. Here we present the design and discuss the test results of a new cryogenic sample environment system for neutron scattering measurements of internal stresses in engineering materials under a load of up to 100 kN and in the temperature range of 6 K to 300 K. Complete cooling of the system starting from the room temperature down to the base temperature takes around 90 min. Understanding of internal stresses in engineering materials at cryogenic temperatures is vital for the modelling and designing of cutting-edge superconducting magnets and other superconductor based applications.

Investigating the Potential of MOOCs in K-12 Teaching and Learning Environments

Science.gov (United States)

Nigh, Jennifer; Pytash, Kristine E.; Ferdig, Richard E.; Merchant, William

2015-01-01

The massive open online course (MOOC) is a relatively new concept in K-12 teaching and learning environments. Although significant work has been done with MOOCs since 2008, it has only been recently that MOOCs have been studied with K-12 populations. The purpose of this study was to further examine the motivation of K-12 students enrolled in a…

Modes of Alphabet Letter Production during Middle Childhood and Adolescence: Interrelationships with Each Other and Other Writing Skills

Directory of Open Access Journals (Sweden)

Zachary Alstad

2015-02-01

Full Text Available Although handwriting is typically taught during early childhood and keyboarding may not be taught explicitly, both may be relevant to writing development in the later grades. Thus, Study 1 investigated automatic production of the ordered alphabet from memory for manuscript (unjoined, cursive (joined, keyboard letter modes (alphabet 15 sec, their relationships with each other, and spelling and composing in typically developing writers in grades 4 to 7 (n =113. Study 2 compared students with dysgraphia (impaired handwriting, n=27, dyslexia (impaired word spelling, n=40, or oral and written language learning disability (OWL LD (impaired syntax composing, n=11 or controls without specific writing disabilities (n=10 in grades 4 to 9 (n=88 on the same alphabet 15 modes, manner of copying, spelling, and sentence composing. In Study 1, sequential multilevel model regressions of predictor alphabet 15 letter production/selection modes on spelling and composition outcomes, measured annually from grade 4 to grade 7 (ages 9 to 13 years, showed that only the cursive mode uniquely, positively, and consistently predicted both spelling and composing in each grade. For composing, in grade 4 manuscript mode was positively predictive and in grades 5-7 keyboard selection was. In Study 2 all letter production modes correlated with each other and one’s best and fast sentence copying, spelling, and timed sentence composing. The groups with specific writing disabilities differed from control group on alphabet 15 manuscript mode, copy fast, and timed sentence composing. The dysgraphia and dyslexia groups differed on copying sentences in one’s best handwriting, with the dysgraphia group scoring lower. The educational and theoretical significance of the findings are discussed for multiple modes and manners of letter production/selection of the alphabet that support spelling and composing beyond the early grades in students with and without specific writing

Problem-Based Learning in the Life Science Classroom, K-12

Science.gov (United States)

McConnell, Tom; Parker, Joyce; Eberhardt, Janet

2016-01-01

"Problem-Based Learning in the Life Science Classroom, K-12" offers a great new way to ignite your creativity. Authors Tom McConnell, Joyce Parker, and Janet Eberhardt show you how to engage students with scenarios that represent real-world science in all its messy, thought-provoking glory. The scenarios prompt K-12 learners to immerse…

Alphabetical: How Every Letter Tells a Story

OpenAIRE

Rosen, Michael

2013-01-01

From minding your Ps and Qs to wondering why X should mark the spot, Alphabetical is a book for everyone who loves words and language. Whether it's how letters are arranged on keyboards or Viking runes, textspeak or zip codes, this book will change the way you think about letters for ever. How on Earth did we fix upon our twenty-six letters, what do they really mean, and how did we come to write them down in the first place? Michael Rosen takes you on an unforgettable adventure through the hi...

A Vision in Aeronautics: The K-12 Wind Tunnel Project

Science.gov (United States)

1997-01-01

A Vision in Aeronautics, a project within the NASA Lewis Research Center's Information Infrastructure Technologies and Applications (IITA) K-12 Program, employs small-scale, subsonic wind tunnels to inspire students to explore the world of aeronautics and computers. Recently, two educational K-12 wind tunnels were built in the Cleveland area. During the 1995-1996 school year, preliminary testing occurred in both tunnels.

Collected software engineering papers, volume 12

Science.gov (United States)

1994-01-01

This document is a collection of selected technical papers produced by participants in the Software Engineering Laboratory (SEL) from November 1993 through October 1994. The purpose of the document is to make available, in one reference, some results of SEL research that originally appeared in a number of different forums. This is the 12th such volume of technical papers produced by the SEL. Although these papers cover several topics related to software engineering, they do not encompass the entire scope of SEL activities and interests. Additional information about the SEL and its research efforts may be obtained from the sources listed in the bibliography at the end of this document.

An Examination of Ideology among Selected K12 Christian School Superintendents

Science.gov (United States)

Dolson, Jimmy L.

2013-01-01

This research project focused on explaining the decision making process of K12 Christian school superintendents whose schools belong to the Association of Christian Schools International (ACSI) organization. In spite of their similar religious and philosophical beliefs, ACSI K12 Christian school superintendents differed significantly in…

K-n and K-p elastic scattering in K-d collisions from 1.2 to 2.2 GeV/c

International Nuclear Information System (INIS)

Declais, Y.; Duchon, J.; Louvel, M.; Patry, J.-P.; Seguinot, J.; Baillon, P.; Bruman, C.; Ferro-Luzzi, M.; Perreau, J.-M.; Ypsilantis, T.

1977-01-01

This report contains the detailed description of an experiment which has determined the differential cross section of the K - n→K - n elastic scattering reaction. The results are 12 angular distributions spanning the K - n c.m. energy interval from approximately 1.86 to approximately 2.32 GeV. The measurements have been performed at the CERN PS using a beam of negative kaons with momenta from 1.2 to 2.2 GeV/c incident on a liquid deuterium target. By means of electronic apparatus the process K - d→K - n psub(s) was identified and recorded; this process is basically the same as the K - n elastic reaction insofar as the spectator proton psub(s) has low momentum. The elastic reaction was derived from the above process by taking into account the Fermi motion of the target neutron and by introducing the appropriate corrections to compensate for the effects due to the composite nature of the neutron (double-scattering, final state interaction). These results, constituting the first extensive collection of data on the pure isospin 1 anti KN state have been used in conjunction with other data in a preliminary partial wave analysis of the anti KN elastic system over the c.m. energy range from 1.84 to 2.23 GeV. Mainly for testing purposes, a similar amount of data has been collected for the K - p elastic reaction also from K - d collisions (K - d→K - p nsub(s)). (Auth.)

46 CFR Table I to Part 150 - Alphabetical List of Cargoes

Science.gov (United States)

2010-10-01

... cargo name), see Caustic potash solution 5 2 CPS Potassium oleate 34 POE Potassium salt of polyolefin... Sodium polyacrylate solution 43 2 Sodium salt of Ferric hydroxyethylethylenediaminetriacetic acid... 46 Shipping 5 2010-10-01 2010-10-01 false Alphabetical List of Cargoes I Table I to Part 150...

Interview with Joe Freidhoff: A Bird's-Eye View of K-12 Online Learning

Science.gov (United States)

Pourreau, Leslie

2015-01-01

The intent of this article is to introduce long-time "Online Learning" readership to the field of K-12 online learning while also providing direction for the K-12 online learning scholars about where the field is going or should be going in terms of meeting the needs of K-12 stakeholders. Recently an interview was conducted with Dr. Joe…

Teacher Perception of Barriers and Benefits in K-12 Technology Usage

Science.gov (United States)

Carver, Lin B.

2016-01-01

This study explores K-12 teachers' perceptions of the benefits and barriers to technology integration by either teachers or students in K-12 instruction. The sample was composed of 68 students enrolled in online classes in the graduate studies in education department of a small private liberal arts institution in the southeast. Data was collected…

The performance of the K10, K6 and GHQ-12 to screen for present state DSM-IV disorders among disability claimants

Directory of Open Access Journals (Sweden)

Cornelius Bert LR

2013-02-01

Full Text Available Abstract Background Screening for mental disorders among disability claimants is important, since mental disorders seem to be seriously under-recognized in this population. However, performance of potentially suitable scales is unknown. We aimed to evaluate the psychometric properties of three scales, the 10- and 6-item Kessler Psychological Distress Scale (K10, K6 and the 12-item General Health Questionnaire (GHQ-12, to predict present state mental disorders, classified according to the Diagnostic and Statistical Manual of Mental Disorders, 4thEdition (DSM-IV among disability claimants. Methods All scales were completed by a representative sample of persons claiming disability benefit after two years sickness absence (n=293. All diagnoses, both somatic and mental, were included. The gold standard was the Composite International Diagnostic Interview (CIDI 3.0 to diagnose present state DSM-IV disorder. Cronbach’s α, sensitivity, specificity, positive (PPV and negative predictive values (NPV, and the areas under the Receiver Operating Characteristic curve (AUC were calculated. Results Cronbach’s alpha’s were 0.919 (K10, 0.882 (K6 and 0.906 (GHQ-12. The optimal cut-off scores were 24 (K10, 14 ( K6 and 20 (GHQ-12. The PPV and the NPV for the optimal cut point of the K10 was 0.53 and 0.89, for the K6 0.51 and 0.87, and for the GHQ-12 0.50 and 0.82. The AUC’s for 30-day cases were 0.806 (K10; 95% CI 0.749-0.862, 0.796 (K6; 95% CI 0.737-0.854 and 0.695 (GHQ-12; 95% CI 0.626-0.765. Conclusions The K10 and K6 are reliable and valid scales to screen for present state DSM-IV mental disorder. The optimal cut-off scores are 24 (K10 and 14 (K6. The GHQ-12 (optimal cut-off score: 20 is outperformed by the K10 and K6, which are to be preferred above the GHQ-12. The scores on separate items of the K10 and K6 can be used in disability assessment settings as an agenda for an in-depth follow-up clinical interview to ascertain the presence of present state

Energy Retrofit for Aging K-12 Schools.

Science.gov (United States)

3D/International, Houston, TX.

Successfully retrofitting aging K-12 schools using energy conservation measures (ECM) that can improve the physical plant and reduce energy consumption are explored. Topics explore how certain ECM measures can benefit educational facilities, why retrofitting begun sooner rather than later is important, how to finance the retrofit program, and the…

ALPHABET "Ante Portas": How English Text Invades Japanese Public Space

Science.gov (United States)

Backhaus, Peter

2007-01-01

This paper examines the prominence of written English on shop signs in Japan. Based on data from a larger empirical study into multilingual signs in Tokyo, the most common ways of using English and the roman alphabet on Japanese shops signs are identified. It is argued that the ambivalent nature of English loan words plays a key role in the ever…

Development of an Attitude Scale to Assess K-12 Teachers' Attitudes toward Nanotechnology

Science.gov (United States)

Lan, Yu-Ling

2012-05-01

To maximize the contributions of nanotechnology to this society, at least 60 countries have put efforts into this field. In Taiwan, a government-funded K-12 Nanotechnology Programme was established to train K-12 teachers with adequate nanotechnology literacy to foster the next generation of Taiwanese people with sufficient knowledge in nanotechnology. In the present study, the Nanotechnology Attitude Scale for K-12 teachers (NAS-T) was developed to assess K-12 teachers' attitudes toward nanotechnology. The NAS-T included 23 Likert-scale items that can be grouped into three components: importance of nanotechnology, affective tendencies in science teaching, and behavioural tendencies to teach nanotechnology. A sample of 233 K-12 teachers who have participated in the K-12 Nanotechnology Programme was included in the present study to investigate the psychometric properties of the NAS-T. The exploratory factor analysis of this teacher sample suggested that the NAS-T was a three-factor model that explained 64.11% of the total variances. This model was also confirmed by the confirmatory factor analysis to validate the factor structure of the NAS-T. The Cronbach's alpha values of three NAS-T subscales ranged from 0.89 to 0.95. Moderate to strong correlations among teachers' NAS-T domain scores, self-perception of own nanoscience knowledge, and their science-teaching efficacy demonstrated good convergent validity of the NAS-T. As a whole, psychometric properties of the NAS-T indicated that this instrument is an effective instrument for assessing K-12 teachers' attitudes toward nanotechnology. The NAS-T will serve as a valuable tool to evaluate teachers' attitude changes after participating in the K-12 Nanotechnology Programme.

Comparison of alphabetical versus categorical display format for medication order entry in a simulated touch screen anesthesia information management system: an experiment in clinician-computer interaction in anesthesia.

Science.gov (United States)

Marian, Anil A; Dexter, Franklin; Tucker, Peter; Todd, Michael M

2012-05-29

Anesthesia information management system (AIMS) records should be designed and configured to facilitate the accurate and prompt recording of multiple drugs administered coincidentally or in rapid succession. We proposed two touch-screen display formats for use with our department's new EPIC touch-screen AIMS. In one format, medication "buttons" were arranged in alphabetical order (i.e. A-C, D-H etc.). In the other, buttons were arranged in categories (Common, Fluids, Cardiovascular, Coagulation etc.). Both formats were modeled on an iPad screen to resemble the AIMS interface. Anesthesia residents, anesthesiologists, and Certified Registered Nurse Anesthetists (n = 60) were then asked to find and touch the correct buttons for a series of medications whose names were displayed to the side of the entry screen. The number of entries made within 2 minutes was recorded. This was done 3 times for each format, with the 1st format chosen randomly. Data were analyzed from the third trials with each format to minimize differences in learning. The categorical format had a mean of 5.6 more drugs entered using the categorical method in two minutes than the alphabetical format (95% confidence interval [CI] 4.5 to 6.8, P < 0.0001). The findings were the same regardless of the order of testing (i.e. alphabetical-categorical vs. categorical - alphabetical) and participants' years of clinical experience. Most anesthesia providers made no (0) errors for most trials (N = 96/120 trials, lower 95% limit 73%, P < 0.0001). There was no difference in error rates between the two formats (P = 0.53). The use of touch-screen user interfaces in healthcare is increasingly common. Arrangement of drugs names in a categorical display format in the medication order-entry touch screen of an AIMS can result in faster data entry compared to an alphabetical arrangement of drugs. Results of this quality improvement project were used in our department's design of our final intraoperative electronic

American Sign Language Alphabet Recognition Using a Neuromorphic Sensor and an Artificial Neural Network

Directory of Open Access Journals (Sweden)

Miguel Rivera-Acosta

2017-09-01

Full Text Available This paper reports the design and analysis of an American Sign Language (ASL alphabet translation system implemented in hardware using a Field-Programmable Gate Array. The system process consists of three stages, the first being the communication with the neuromorphic camera (also called Dynamic Vision Sensor, DVS sensor using the Universal Serial Bus protocol. The feature extraction of the events generated by the DVS is the second part of the process, consisting of a presentation of the digital image processing algorithms developed in software, which aim to reduce redundant information and prepare the data for the third stage. The last stage of the system process is the classification of the ASL alphabet, achieved with a single artificial neural network implemented in digital hardware for higher speed. The overall result is the development of a classification system using the ASL signs contour, fully implemented in a reconfigurable device. The experimental results consist of a comparative analysis of the recognition rate among the alphabet signs using the neuromorphic camera in order to prove the proper operation of the digital image processing algorithms. In the experiments performed with 720 samples of 24 signs, a recognition accuracy of 79.58% was obtained.

Control of 12-Cylinder Camless Engine with Neural Networks

OpenAIRE

Ashhab Moh’d Sami

2017-01-01

The 12-cyliner camless engine breathing process is modeled with artificial neural networks (ANN’s). The inputs to the net are the intake valve lift (IVL) and intake valve closing timing (IVC) whereas the output of the net is the cylinder air charge (CAC). The ANN is trained with data collected from an engine simulation model which is based on thermodynamics principles and calibrated against real engine data. A method for adapting single-output feed-forward neural networks is proposed and appl...

Inspiring the Next Generation: Astronomy Catalyzes K12 STEM Education

Science.gov (United States)

Borders, Kareen; Thaller, Michelle; Winglee, Robert; Borders, Kyla

2017-06-01

K-12 educators need effective and relevant astronomy professional development. NASA's Mission Science provides innovative and accessible opportunities for K-12 teachers. Science questions involve scale and distance, including Moon/Earth scale, solar system scale, and distance of objects in the universe. Teachers can gain an understanding of basic telescopes, the history of telescopes, ground and satellite based telescopes, and models of JWST Telescope. An in-depth explanation of JWST and Spitzer telescopes gave participants background knowledge for infrared astronomy observations. During teacher training, we taught the electromagnetic spectrum through interactive stations. The stations included an overview via lecture and power point, the use of ultraviolet beads to determine ultraviolet exposure, the study of lenticulars and diagramming of infrared data, looking at visible light through diffraction glasses and diagramming the data, protocols for using astronomy based research in the classroom, and infrared thermometers to compare environmental conditions around the observatory. An overview of LIDAR physics was followed up by a simulated LIDAR mapping of the topography of Mars.We will outline specific steps for K-12 infrared astronomy professional development, provide data demonstrating the impact of the above professional development on educator understanding and classroom use, and detail future plans for additional K-12 professional development.Funding was provided by Washington STEM, NASA, and the Washington Space Grant Consortium.

Laser-induced incandescence measurements in a fired diesel engine at 3 kHz

Science.gov (United States)

Boxx, I. G.; Heinold, O.; Geigle, K. P.

2015-01-01

Laser-induced incandescence (LII) was performed at 3 kHz in an optically accessible cylinder of a fired diesel engine using a commercially available diode-pumped solid-state laser and an intensified CMOS camera. The resulting images, acquired every 3° of crank angle, enabled the spatiotemporal tracking of soot structures during the expansion/exhaust stroke of the engine cycle. The image sequences demonstrate that soot tends to form in thin sheets that propagate and interact with the in-cylinder flow. These sheets tend to align parallel to the central axis of the cylinder and are frequently wrapped into conical spirals by aerodynamic swirl. Most of the soot is observed well away from the cylinder walls. Quantitative soot measurements were beyond the scope of this study but the results demonstrate the practical utility of using kHz-rate LII to acquire ensemble-averaged statistical data with high crank angle resolution over a complete engine cycle. Based on semi-quantitative measures of soot distribution, it was possible to identify soot dynamics related to incomplete charge exchange. This study shows that long-duration, multi-kHz acquisition rate LII measurements are viable in a fired diesel engine with currently available laser and camera technology, albeit only in the expansion and exhaust phase of the cycle at present. Furthermore, such measurements yield useful insight into soot dynamics and therefore constitute an important new tool for the development and optimization of diesel engine technology.

Teaching Beginning Braille Reading Using an Alphabet or Uncontracted Braille Approach

Science.gov (United States)

Day, Janice Neibaur; McDonnell, Andrea P.; O'Neill, Rob

2008-01-01

This study examined the effects of using a research based print reading program modified to accommodate beginning braille readers using an alphabet or uncontracted braille reading approach with five beginning braille readers. Four of the 5 participants displayed a clear increase in their ability to read high frequency words when they began using…

The SERC K12 Educators Portal to Teaching Activities and Pedagogic Approaches

Science.gov (United States)

Larsen, K.; Kirk, K. B.; Manduca, C. A.; Ledley, T. S.; Schmitt, L.

2013-12-01

The Science Education Resource Center (SERC) has created a portal to information for K12 educators to provide high-quality grade level appropriate materials from a wide variety of projects and topics. These materials were compiled across the SERC site, showcasing materials that were created for, or easily adaptable to, K12 classrooms. This resource will help support implementation of Next Generation Science Standards by assisting educators in finding innovative resources to address areas of instruction that are conceptually different than previous national and state science standards. Specifically, the K12 portal assists educators in learning about approaches that address the cross-cutting nature of science concepts, increasing students quantitative reasoning and numeracy skills, incorporating technology such as GIS in the classroom, and by assisting educators of all levels of K12 instruction in using relevant and meaningful ways to teach science concepts. The K12 portal supports educators by providing access to hundreds of teaching activities covering a wide array of science topics and grade levels many of which have been rigorously reviewed for pedagogic quality and scientific accuracy. The portal also provides access to web pages that enhance teaching practices that help increase student's system thinking skills, make lectures interactive, assist instructors in conducting safe and effective indoor and outdoor labs, providing support for teaching energy and climate literacy principles, assisting educators in addressing controversial content, provide guidance in engaging students affective domain, and provides a collection of tools for making teaching relevant in 21st century classrooms including using GIS, Google Earth, videos, visualizations and simulations to model and describe scientific concepts. The portal also provides access to material for specific content and audiences by (1) Supporting AGIs 'Map your World' week to specifically highlight teaching

A Groundwater project for K-12 schools: Bringing research into the classroom

Science.gov (United States)

Rodak, C. M.; Walsh, M.; Gensic, J.

2011-12-01

Simple water quality test kits were used in a series of K-12 classrooms to demonstrate scientific processes and to motivate learning in K-12 students. While focused on student learning, this project also allowed collection of regional data on groundwater quality (primarily nitrate) in the study area. The project consisted of development and administration of a weeklong groundwater quality unit introduced to K-12 schools in northern Indiana and taught by a graduate student in an engineering discipline. The structure of the week started with an introduction to basic groundwater concepts modified for the specific grade level; for this project the students ranged from grades 4-12. In addition to groundwater basics, the purpose of the collection of the water quality data, as well as relevance to the research of the graduate student, were outlined. The students were then: (i) introduced to two simple water quality testing methods for nitrates, (ii) required to hypothesize as to which method will likely be "better" in application, and (iii) asked to practice using these two methods under laboratory conditions. Following practice, the students were asked to discuss their hypotheses relative to what was observed during the practice focusing on which testing method was more accurate and/or precise. The students were then encouraged to bring water samples from their home water system (many of which are on private wells) to analyze within groups. At the end of the week, the students shared their experience in this educational effort, as well as the resulting nitrate data from numerous groundwater wells (as collected by the students). Following these discussions the data were added to an online database housed on a wiki sponsored by the Notre Dame Extended Research Community (http://wellhead.michianastem.org/home). These data were plotted using the free service MapAList to visually demonstrate to the students the spatial distribution of the data and how their results have

Approaching K-12 Online Education in Pennsylvania

Science.gov (United States)

Vadell, Kathryn

2013-01-01

The purpose of this study is to determine how K-12 schools are addressing the need to accommodate online learners in Pennsylvania. It is built upon a review of literature focusing on educational legislation, the personalization of online learning and online learning solutions. The study posed 21 questions utilizing a mixed methods approach to…

Scientists Involved in K-12 Education

Science.gov (United States)

Robigou, V.

2004-12-01

The publication of countless reports documenting the dismal state of science education in the 1980s, and the Third International Mathematics and Science Study (TIMMS) report (1996) called for a wider involvement of the scientific community in K-12 education and outreach. Improving science education will not happen without the collaboration of educators and scientists working in a coordinated manner and it requires a long-term, continuous effort. To contribute effectively to K-12 education all scientists should refer to the National Science Education Standards, a set of policies that guide the development of curriculum and assessment. Ocean scientists can also specifically refer to the COSEE recommendations (www.cosee.org) that led to the creation of seven regional Centers for Ocean Sciences Education Excellence. Scientists can get involved in K-12 education in a multitude of ways. They should select projects that will accommodate time away from their research and teaching obligations, their talent, and their interest but also contribute to the education reform. A few examples of effective involvement are: 1) collaborating with colleagues in a school of education that can lead to better education of all students and future teachers, 2) acting as a resource for a national program or a local science fair, 3) serving on the advisory board of a program that develops educational material, 4) speaking out at professional meetings about the value of scientists' involvement in education, 5) speaking enthusiastically about the teaching profession. Improving science education in addition to research can seem a large, overwhelming task for scientists. As a result, focusing on projects that will fit the scientist's needs as well as benefit the science reform is of prime importance. It takes an enormous amount of work and financial and personnel resources to start a new program with measurable impact on students. So, finding the right opportunity is a priority, and stepping

Observation of Λ-hypernuclei in the reaction 12C(π+,K+)/sub Λ/12C

International Nuclear Information System (INIS)

Milner, E.C.

1985-12-01

The observation of Λ-hypernuclear levels in /sub Λ/ 12 C by associated production through the (π + ,K + ) reaction is reported. Spectrometers used in the measurements are discussed. The /sub Λ/ 12 C excitation energy spectra were recorded at laboratory scattering angles of 5.6 0 , 10.3 0 , and 15.2 0 . The spectra show two major peaks - one attributed to the ground state, and one about 11 MeV higher in excitation. The peak near 11 MeV excitation energy is believed to be almost entirely composed of a multiplet of three J/sup π/ = 2 + states. Relativistic DWBA calculations imply support for the expectation that higher spin states are preferentially populated in the (π + ,K + ) reaction, compared to the (K - ,π - ) reaction in which lower spin states are excited. 29 refs., 40 figs

Cyrillic alphabet as the designation of national identity among students of University of Priština with temporary head office in Kosovska Mitrovica

Directory of Open Access Journals (Sweden)

Miketić Sanja D.

2016-01-01

Full Text Available The relationship between culture and nationality and in that sense - national identity of a particular community - is a known thing for a long time. Nationality is usually strongly connected to culture. We will only mention few of their joint characteristics: language, religion, art, customs, tradition etc. In this article special attention will be paid to one of the features of national identity - language - and we will focus on the usage of Cyrillic alphabet of our target group (students of University of Priština, with temporary head office in Kosovska Mitrovica. The study consists of two smaller researches. In the first part we explored reactions of students at University of Priština and we assumed that they will have different reactions towards Cyrillic alphabet and Latin alphabet used as stimuli-words comparing to pupils of Belgrade and Zrenjanin high schools and students of University of Belgrade, Novi Sad and Niš presented in The associative dictionary of Serbian language (Asocjativni rečnik srpskog jezika, 2005. In the second part we tried to find out if our informants prefer the usage of Cyrillic or Latin alphabet, and which one they find better in the esthetic sense. We compared attitudes of students who enroll University of Priština to attitudes of students who enroll University of Belgrade and differences between their attitudes. With both researches we wanted to see if there are formed verbal stereotypes with positive or negative connotation, and what are the attitudes on using Cyrillic alphabet among students in the age of expansion of Latin alphabet. We concluded that Cyrillic alphabet is more used and valued at University of Priština than in the rest of Republic of Serbia and the reason for that might be the stronger sense of national identity among these students.

K/sup -/n and K/sup -/p elastic scattering in K/sup -/d collisions from 12 to 22 GeV/c

CERN Document Server

Déclais, Y; Bricman, C; Duchon, J; Ferro-Luzzi, M; Louvel, M; Patry, J P; Perreau, J M; Séguinot, Jacques; Ypsilantis, Thomas

1977-01-01

The elastic scattering of negative K-mesons on the proton and on the neutron of the deuterium has been measured at six incident momenta equally spaced between 1.2 and 2.2 GeV/c. Differential cross sections over the almost complete angular range have been obtained for K/sup - /p and K/sup -/n. The aim of the experiment was the measurement of the pure isospin I=1 reaction K/sup -/n to K/sup -/n. The results for the reaction on proton are a by-product and provide a verification of the assumptions necessary for the analysis of the neutron reaction.

K-12 Education Nonprofit Employees' Perceptions of Strategies for Recruiting and Retaining Employees

Science.gov (United States)

Byrne, Tara Marie

2013-01-01

This qualitative study explored the key reasons individuals who work in K-12 education nonprofit organizations enter the field of K-12 nonprofit education and their motivations for doing so. The purpose of this study was to find new strategies for recruiting and retaining K-12 education nonprofit employees by examining the obstacles that exist to…

Lon gene and photoprotection in Escherichia coli K-12

Energy Technology Data Exchange (ETDEWEB)

Waksman, G.; Thomas, G.; Favre, A. (Institut de Recherche en Biologie Moleculaire, Group de Photobiologie Moleculaire, Paris (France))

1984-03-01

Photoprotection, i.e. the increased resistance of the cells preilluminated with near ultraviolet light (300-380 nm) to the lethal action of 254nm radiations requires either an integrated prophage or a recA mutation in Escherichia coli K12 strains. Significant photoprotection occurs in an Escherichia coli K12 recA/sup +/ cell containing the lon allele responsible for filamentous growth after 254nm irradiation. The Fil phenotype can be suppressed by the sfiA or sfiB suppressor genes. Since the E. coli K12 recA/sup +/ lon sfiB strain exhibits no more photoprotection, it is concluded that in lon strains photoprotection is due to the abolition of the 254nm induced filamentation by the near ultraviolet treatment. In addition, near ultraviolet illumination of the cells leads to a severe restriction of the bulk protein synthesis. This effect is observed only in nuv/sup +/ cells that contain 4-thiouridine the chromophore responsible for photoprotection. It is proposed that in lon (lysogenic strains) photoprotection is due to prevention of the SOS response. During the growth lag, the low residual level of protein synthesis does not allow the induction of the SOS response and accordingly prevents filamentation (the lytic cycle).

Armed To Learn: Aiming At California K 12 School Gun Policy

Science.gov (United States)

2016-03-01

AIMING AT CALIFORNIA K-12 SCHOOL GUN POLICY by Catherine Wilson Jones March 2016 Thesis Co-Advisors: Kathleen Kiernan John Rollins...Master’s thesis 4. TITLE AND SUBTITLE ARMED TO LEARN: AIMING AT CALIFORNIA K-12 SCHOOL GUN POLICY 5. FUNDING NUMBERS 6. AUTHOR(S) Catherine...gap in viewpoints between gun control advocates who want tighter gun control and constitutionalists who believe as strongly in the Second Amendment

Contributions to the 12th. International Cryogenic Engineering Conference

International Nuclear Information System (INIS)

Anon.

1988-01-01

The report consists of two papers read at the 12 th International Cryogenic Engineering Conference Held in Southampton from 12 to 15 July 1988. The first deals with the design of a conductor for NET machine; the second one gives the description of the liquid Nitrogen cooling system of the FTU tokamak

[Carcinogenesis and its mechanism of mutant-type[12Asp]K-ras4B gene].

Science.gov (United States)

Gui, Li-ming; Wei, Li-hui; Zhang, Ying-mei; Wang, Jian-liu; Wang, Ying; Chen, Ying; Ma, Da-long

2002-01-01

Ras gene plays an important role in the extra- and intra-cellular signal transduction pathway. It mediates series cascade reactions, and eventually actives transcriptional factors in nucleus. It is unknown on the mechanism of carcinogenesis of Ras gene in endometrial carcinoma, though K-ras mutant is very common in endometrial atypical hyperplasia and carcinoma. On basis of discovering the mutation in 12th codon of K-ras in endometrial carcinoma cell line, HEC-1A, we explored the carcinogenesis and molecular mechanism of mutant-type [12Asp] K-ras4B gene. (1) Full-length [12Asp]K-ras4B cDNA was amplified with RT-PCR, then inserted into pcDI eukaryotic expressive vector. (2) Morphological change, growth kinetics in vitro and tumorigencity in nude mice in vivo after-before transfection were observed. (3) To test the cell growth kinetics by methyl thiazolium tetrazolium (MTT) and [3H]thymidine incorporation method. (1) The authors have successfully constructed eukaryotic expression plasmid pcDI-[12Asp] K-ras4B; (2) To confirm that [12Asp] K-ras4B mutant can trigger the neoplastic transformation of NIH3T3 cells by test in vitro and in vivo. (3) After pMCV-RasN17 plasmid, a Ras mutant were transfected into pcDI-[12Asp] K-ras4B cells, the growth of this cell were restrained significantly in comparison with control group. (4) These findings indicate the expression of RafS621A resulted in remarkable inhibition in proliferation of pcDI-[12Asp]K-ras4B cell (P ras4B cell growth (P ras4B gene alone is able to cause neoplastic transformation in NIH3T3 cells in vitro and in vivo. (2) [12Asp]K-ras4B-induced NIH3T3 cells neoplastic transformation required Raf signaling pathway.

Iteration in Early-Elementary Engineering Design

Science.gov (United States)

McFarland Kendall, Amber Leigh

2017-01-01

K-12 standards and curricula are beginning to include engineering design as a key practice within Science Technology Engineering and Mathematics (STEM) education. However, there is little research on how the youngest students engage in engineering design within the elementary classroom. This dissertation focuses on iteration as an essential aspect…

The Green Pages: Environmental Education Activities K-12.

Science.gov (United States)

Clearing, 1990

1990-01-01

Presented are 37 environmental science activities for students in grades K-12. Topics include water pollution, glaciers, protective coloration, shapes in nature, environmental impacts, recycling, creative writing, litter, shapes found in nature, color, rain cycle, waste management, plastics, energy, pH, landfills, runoff, watersheds,…

Perceptual Confusions of the Manual Alphabet by Naive, Trained, and Familiar Users.

Science.gov (United States)

Hawes, M. Dixie; Danhauer, Jeffrey L.

1980-01-01

An investigation of the confusion resulting from reliance on visual perceptual teachers in the identification of dactylemes (handshapes) in the American Manual Alphabet (MA) is reported. A hierarchy of errors varying with subjects' degree of expertness in the MA is established. This can help manual communication teachers develop techniques for…

Integration of Engineering Education by High School Teachers to Meet Standards in the Physics Classroom

Science.gov (United States)

Kersten, Jennifer Anna

2013-01-01

In recent years there has been increasing interest in engineering education at the K-12 level, which has resulted in states adopting engineering standards as a part of their academic science standards. From a national perspective, the basis for research into engineering education at the K-12 level is the belief that it is of benefit to student…

The Effects of Shona Language Change on Monolingual Lexicography: The Need for a Revised Alphabet

Directory of Open Access Journals (Sweden)

William Zivenge

2011-10-01

Full Text Available

ABSTRACT: In this article, the phenomenon of Shona language change, its effects on lexicography and the need for a revised alphabet are discussed. Because of the defective Shona alphabet, lexicographers at the African Languages Research Institute (ALRI encountered problems in handling some words that were potential headwords in dictionaries they were compiling under the ALLEX project. The current Shona alphabet is unable to realize quite a number of sounds and morphemes in lexical items in everyday use by the native Shona speakers, because they are alien loanwords. The article was prompted by the challenges encountered during the compilation of Duramazwi reMimhanzi (Shona Musical Terms Dictionary. It shows how language change accounts for the problem of headword selection and how modifying the current alphabet can enhance monolingual Shona lexicographical work vis-à-vis the development of the Shona language. It therefore stresses the need for a revised alphabet so as to solve orthographical problems during dictionary compilation.

PFUPISO YECHINYORWA: Matambudziko Anosanganwa Nawo Mukugadzira Maduramazwi eMutauro Mumwe chete neKuda Kwekushanduka Kwemutauro weChiShona: Panofanirwa Kuva neManyorerwo eChiShona Matsva. Muchinyorwa chino vanyori vanoongorora kushanduka kuri kuita mutauro weChiShona nekufamba kuri kuita nguva nematambudziko anosanganikwa nawo nekuda kweshanduko iyi zvikurusei mukugadzira maduramazwi ari mururimi rweChiShona chete. Vanyori vanoonesawo pfungwa yekuti panodiwa manyorerwo matsva. Nyanzvi dzinogadzira maduramazwi paAfrican Languages Research Institute (ALRI dzinosangana namadambudziko esarudzo yamazwi padzinenge dzichisarudza mazwi adzinenge dzichida kuisa mumaduramazwi adzinogadzira pachirongwa chokugadzira maduramazwi chinonzi ALLEX. Dambudziko resarudzo yemazwi rinowanikwa nekuda kwechimiro chebumbiro remanyorerwo eChiShona risingatenderi mamwe mavara ari mune imwe mitauro asiri muChiShona. Bumbiro iri

K-12 Online Learning and the Training Needs for School Psychology Practitioners

Science.gov (United States)

Tysinger, P. Dawn; Tysinger, Jeff; Diamanduros, Terry; Kennedy, Kathryn

2013-01-01

K-12 online learning is growing at an exponential rate in the United States and around the world. Students and teachers are entering and embracing the K-12 online learning environment. Thus, it becomes imperative for school psychologists to follow. In order to offer the most productive learning environment for all students, the services provided…

Generic vs. Modality-Specific Competencies for K-12 Online and Blended Teaching

Science.gov (United States)

Pulham, Emily B.; Graham, Charles R.; Short, Cecil R.

2018-01-01

Although research has explored teacher competencies in K-12 blended and online learning, it has not specified which competencies are appropriate to an online or digital medium, which refer to blending in-person with online experiences, or which are generic--applicable in any teaching modality. This article explores selected K-12 online and blended…

K-12 Teachers' Perceptions of School Policy and Fear of School Violence

Science.gov (United States)

Ricketts, Melissa L.

2007-01-01

Since the 1990s, schools have focused their attention on policies designed to improve school safety. Most researches on school violence policies have concentrated on the needs of students and administrators. This study investigated the impact of school violence policies on K-12 teachers' fear. Using self-report data from 447 K-12 teachers from a…

Opinions on Computing Education in Korean K-12 System: Higher Education Perspective

Science.gov (United States)

Kim, Dae-Kyoo; Jeong, Dongwon; Lu, Lunjin; Debnath, Debatosh; Ming, Hua

2015-01-01

The need for computing education in the K-12 curriculum has grown globally. The Republic of Korea is not an exception. In response to the need, the Korean Ministry of Education has announced an outline for software-centric computing education in the K-12 system, which aims at enhancing the current computing education with software emphasis. In…

GABAB receptor phosphorylation regulates KCTD12-induced K+ current desensitization

DEFF Research Database (Denmark)

Adelfinger, L; Turecek, R; Ivankova, K

2014-01-01

released from the G-protein. Receptor-activated K+ currents desensitize in the sustained presence of agonist to avoid excessive effects on neuronal activity. Desensitization of K+ currents integrates distinct mechanistic underpinnings. GABAB receptor activity reduces protein kinase-A activity, which...... reduces phosphorylation of serine-892 in GABAB2 and promotes receptor degradation. This form of desensitization operates on the time scale of several minutes to hours. A faster form of desensitization is induced by the auxiliary subunit KCTD12, which interferes with channel activation by binding to the G......-protein βγ subunits. Here we show that the two mechanisms of desensitization influence each other. Serine-892 phosphorylation in heterologous cells rearranges KCTD12 at the receptor and slows KCTD12-induced desensitization. Likewise, protein kinase-A activation in hippocampal neurons slows fast...

Index to UKAEA, BNFL, MOD(PE) AWRE and recommended external standards

International Nuclear Information System (INIS)

1977-11-01

The principal part of the document consists of an alphabetical index and numerical index to United Kingdom Atomic Energy Authority, British Nuclear Fuels Limited, and Atomic Weapons Research Establishment standards, engineering and general stores. Also included are: an index to Engineering Equipment Users Association handbooks and documents, members' specifications, codes of practice and handbooks; British Standard Codes of practice (for building, electrical engineering, civil engineering, mechanical engineering); UKAEA Standardisation Committee memoranda and metric guides; and miscellaneous documents. (U.K.)

Producer gas fuelling of a 20kW output engine by gasification of solid biomass

Energy Technology Data Exchange (ETDEWEB)

Hollingdale, A C; Breag, G R; Pearce, D

1988-11-01

Motive power requirements in the range up to 100 kW shaft power are common in developing country processing operations. Producer gas-fuelled systems based upon a relatively cheap and simple manually operated gasifier or reactor using readily available biomass feedstock can offer in some cases an attractive alternative to fossil-fuelled power units. This bulletin outlines research and development work by the Industrial Development Department of the Overseas Development Natural Resources Institute for 20 kW shaft power output from producer gas derived from solid biomass. Biomass materials such as wood or shells can be carbonized to form charcoal or left in the natural uncarbonized state. In this work both carbonized and uncarbonized biomass fuel has been used to provide producer gas to fuel a Ford 2274E engine, an industrial version of a standard vehicle spark-ignition engine. Cross-draught and down-draught reactor designs were evaluated during trials with this engine. Also different gas cleaning and cooling arrangements were tested. Particular emphasis was placed on practical aspects of reactor/engine operation. This work follows earlier work with a 4 kW shaft power output system using charcoal-derived producer gas. (author).

Exploring the evolution of standard amino-acid alphabet: When genomics meets thermodynamics

International Nuclear Information System (INIS)

Zhang, Hong-Yu

2007-01-01

One of the most intriguing aspects of life is that despite the diversified apparent shapes, similar building blocks and infrastructures, such as standard amino acids and canonical genetic codes, are shared by most life on Earth. Thus, it is challenging to explore: why nature just selects these building blocks and strategies from numerous candidates to construct life? Was this deterministic or fortuitous? Thanks to the rapid progress in genomics, bioinformatics and synthetic biology, more and more basic principles underlying life design and construction were disclosed in the past decade. However, since the origin of early life is substantially a chemical process, to understand the enigma of life origin, chemists' efforts can not be neglected. In this paper, we focus on the evolution of standard amino-acid alphabet and indicate that chemistry, especially thermodynamics, is indeed critical to understanding the forming mechanisms of amino-acid alphabet. It is revealed that nature prefers low free energy and thus ubiquitous (cheap) small amino acids when beginning to build life, which is compatible with many recent findings from genomics and bioinformatics

Evaluating the Performance of Online K-12 Schools

Science.gov (United States)

Carpenter, Dick; Kafer, Krista; Reeser, Kelly; Shafer, Sheryl

2015-01-01

This article examines K-12 online student and school performance across an entire state (Colorado) in the United States through two comparisons. First, state assessment scores of students in online schools are compared to those in traditional brick and mortar schools. Second, the accountability scores of online schools are compared to those of…

Designing GIS Learning Materials for K-12 Teachers

Science.gov (United States)

Hong, Jung Eun

2017-01-01

Although previous studies have proven the usefulness and effectiveness of geographic information system (GIS) use in the K-12 classroom, the rate of teacher adoption remains low. The identified major barrier to its use is a lack of teachers' background and experience. To solve this limitation, many organisations have provided GIS-related teacher…

What do K-12 students feel when dealing with technology and engineering issues? Gardner's multiple intelligence theory implications in technology lessons for motivating engineering vocations at Spanish Secondary School

Science.gov (United States)

Sánchez-Martín, Jesús; Álvarez-Gragera, García J.; Dávila-Acedo, M. Antonia; Mellado, Vicente

2017-11-01

The interest on engineering and scientific studies can be raised up even from the early years of academic instructional process. This vocation may be linked to emotions and aptitudes towards technological education. Particularly, students get in touch with these technological issues (namely STEM) during the Compulsory Secondary Education in Spain (12-16 years old).This work presents a preliminary evaluation of how relevant is Gardner's multiple intelligence theory (MIT) in the teaching-learning process within the Technology Lessons. In this sense, MIT was considered as an explanation variable of the emotional response within the different educational parts (so-called syllabus units, SU) in the Technology spanish curriculum. Different intelligence style (IS) will orient the student to a vision of the engineering and technology. This work tries to identify which relationships can be established between IS and specific technology and engineering learning. This research involved up to 135 students were subsequently tested about their predominant (IS) and on the emotions that arouse in them when working with each SU. The results were statistically significant and only those with a Logic-arithmetic or Environmental IS were not affected by the SU.Best teaching and learning practicesare required for encouraging further engineering studies.

Effects of paraquat on Escherichia coli: Differences between B and K-12 strains

International Nuclear Information System (INIS)

Kitzler, J.W.; Minakami, H.; Fridovich, I.

1990-01-01

Escherichia coli B and K-12 are equally susceptible to the bacteriostatic effects of aerobic paraquat, but they differed strikingly when the lethality of paraquat was evaluated. E. coli B suffered an apparent loss of viability when briefly exposed to paraquat, whereas E. coli K-12 did not. This difference depended on the ability of the B-strain, but not the K-12 strain, to retain internalized paraquat; the B strain was killed on aerobic tryptic soy-yeast extract plates during the incubation which preceded the counting of colonies. This difference in retention of paraquat between strains was demonstrated by delayed loss of viability, by growth inhibition, and by cyanide-resistant respiration after brief exposure to paraquat, washing, and testing in fresh medium. This difference was also shown by using [ 14 C]paraquat. This previously unrecognized difference between E. coli B and K-12 has been the cause of apparently contradictory reports and should lead to some reevaluation of the pertinent literature

Native American Indian Successes in Natural Resources, Science and Engineering: PreK through Ph.D.

Science.gov (United States)

Bolman, J. R.

2005-12-01

We are living in a definite time of change. Distinct changes are being experienced in our most sacred and natural environments. This is especially true on Native lands. Native people have lived for millennia in distinct and unique ways. The knowledge of balancing the needs of people with the needs of our natural environments is paramount in all tribal societies. This inherent knowledge has become the foundation on which to build a "blended" contemporary understanding of western science. The Dakota's and Northern California have recognized the critical need in understanding successful tribal strategies to engage educational systems (K-12 and higher education), to bring to prominence the professional development opportunities forged through working with tribal peoples and ensure the growth of Native people in STEM (Science, Technology, Engineering and Mathematics) professions. The presentation will highlight: 1) current philosophies on building a STEM Native workforce; 2) successful educational programs/activities in PreK-Ph.D. systems; 3) current Native professionals, their research and tribal applicability; and 4) forwarding thinking for creating sustainable environmental and social infrastructures for all people. South Dakota School of Mines and Technology (SDSM&T) and Humboldt State University (HSU) have been recognized nationally for their partnerships with Native communities. SDSM&T has set record numbers for graduating Native students in science and engineering. SDSM&T had 27 graduates in five years (2000-2005) and hosted more than 1000+ Native students for programs and activities. Humboldt State University is the only university in the CSU system with a program focusing specifically on Natives in natural resources, science and engineering as well as a Native American Studies degree. Both universities have designed programs to meet current needs and address challenging issues in Earth, Wind, Fire and Water. The programs are funded through NASA, NSF, NIH and

Theoretical assessment of the electro-optical features of the group III nitrides (B{sub 12}N{sub 12}, Al{sub 12}N{sub 12} and Ga{sub 12}N{sub 12}) and group IV carbides (C{sub 24}, Si{sub 12}C{sub 12} and Ge{sub 12}C{sub 12}) nanoclusters encapsulated with alkali metals (Li, Na and K)

Energy Technology Data Exchange (ETDEWEB)

Tahmasebi, Elham [Chemistry Department, Faculty of Science, Lorestan University, Khorram Abad, Lorestan (Iran, Islamic Republic of); Shakerzadeh, Ehsan, E-mail: e.shakerzadeh@scu.ac.ir [Chemistry Department, Faculty of Science, Shahid Chamran University, Ahvaz (Iran, Islamic Republic of); Biglari, Zeinab [Chemistry Department, Faculty of Science, Lorestan University, Khorram Abad, Lorestan (Iran, Islamic Republic of)

2016-02-15

Graphical abstract: - Highlights: • Encapsulation of Li, Na and K narrow the HOMO–LUMO gaps of the clusters. • The group III nitrides nanoclusters strongly interacted with the alkali metals. • First hyperpolarizabilities remarkably enhance for B{sub 12}N{sub 12} encapsulated with Na/K. - Abstract: Density functional theory (DFT) calculations have been carried out to study the influence of alkali metals (Li, Na and K) encapsulation within the group III nitrides (B{sub 12}N{sub 12}, Al{sub 12}N{sub 12} and Ga{sub 12}N{sub 12}) and the group IV carbides (C{sub 24}, Si{sub 12}C{sub 12}and Ge{sub 12}C{sub 12}) nanoclusters. The encapsulation of Li, Na and K atoms is found to narrow the HOMO–LUMO gaps of the considered clusters. The electronic properties of these clusters, especially the group III nitrides nanoclusters, are strongly sensitive to interaction with the alkali metals. Moreover it is observed that the encapsulation of alkali metals enhances the first hyperpolarizabilities of B{sub 12}N{sub 12} nanocluster. Surprisingly, due to the alkali metals encapsulation within B{sub 12}N{sub 12} nanocluster, the first hyperpolarizability values are remarkably increased to 8505.49 and 122,503.76 a.u. for Na@B{sub 12}N{sub 12} and K@B{sub 12}N{sub 12}, respectively. Also the TD-DFT calculations at both CAM-B3LYP/6-311+G(d) and PBE0/6-311+G(d) levels of theory are also performed to investigate the origin of first hyperpolarizabilities.

Effective Teaching Strategies: Case Studies from the Alphabetic Braille and Contracted Braille Study

Science.gov (United States)

Barclay, Lizbeth; Herlich, Stephanie A.; Sacks, Sharon Zell

2010-01-01

This article discusses some of the qualitative data that were documented during the Alphabetic Braille and Contracted Braille Study. Two case studies of students are described, highlighting many effective teaching strategies used by their teachers of students with visual impairments that resulted in the students' successful academic progress.…

5-kWe Free-piston Stirling Engine Convertor

Science.gov (United States)

Chapman, Peter A.; Vitale, Nicholas A.; Walter, Thomas J.

2008-01-01

The high reliability, long life, and efficient operation of Free-Piston Stirling Engines (FPSEs) make them an attractive power system to meet future space power requirements with less mass, better efficiency, and less total heat exchanger area than other power convertor options. FPSEs are also flexible in configuration as they can be coupled with many potential heat sources and various heat input systems, heat rejection systems, and power management and distribution systems. Development of a 5-kWe Stirling Convertor Assembly (SCA) is underway to demonstrate the viability of an FPSE for space power. The design is a scaled-down version of the successful 12.5-kWe Component Test Power Converter (CTPC) developed under NAS3-25463. The ultimate efficiency target is 25% overall convertor efficiency (electrical power out over heat in). For the single cylinder prototype now in development, cost and time constraints required use of economical and readily available materials (steel versus beryllium) and components (a commercially available linear alternator) and thus lower efficiency. The working gas is helium at 150 bar mean pressure. The design consists of a displacer suspended on internally pumped gas bearings and a power piston/alternator supported on flexures. Non-contacting clearance seals are used between internal volumes. Heat to and from the prototype convertor is done via pumped liquid loops passing through shell and tube heat exchangers. The preliminary and detail designs of the convertor, controller, and support systems (heating loop, cooling loop, and helium supply system) are complete and all hardware is on order. Assembly and test of the prototype at Foster- Miller is planned for early 2008, when work will focus on characterizing convertor dynamics and steady-state operation to determine maximum power output and system efficiency. The device will then be delivered to Auburn University where assessments will include start-up and shutdown characterization and

Designer Librarian: Embedded in K12 Online Learning

Science.gov (United States)

Boyer, Brenda

2015-01-01

Over the past two decades, shifts in technology have altered the roles of school librarians in a multitude of ways. New rigorous standards, proliferation of devices, and steady growth of online and blended learning for the K12 market now demand librarians engage with learners in online environments. Taking an instructional design approach is the…

Online System Adoption and K-12 Academic Outcomes

Science.gov (United States)

Kimmons, R.

2015-01-01

This study seeks to understand the relationship between K-12 online system adoption (e.g., Blackboard, Edmodo, WordPress) and school-level academic achievement ratings. Utilizing a novel approach to data collection via website data extraction and indexing of all school websites in a target state in the United States (n?=?732) and merging these…

Florida's Opinion on K-12 Public Education Spending

Science.gov (United States)

Forster, Greg

2006-01-01

This scientifically representative poll of 1,200 Floridians finds that public opinion about K-12 public education spending is seriously misinformed. Floridians think public schools need more money, but the main reason is that they are badly mistaken about how much money the public schools actually get. Key findings of the study include: (1) Half…

Power cables with extruded insulation and their accessories for rated voltages from 1 kV (Um = 1,2 kV) up to 30 kV (Um = 36 kV) : Part 2: cables for rated voltages from 6 kV (Um = 7,2 kV) up to 30 kV (Um = 36 kV)

CERN Document Server

International Electrotechnical Commission. Geneva

2005-01-01

Power cables with extruded insulation and their accessories for rated voltages from 1 kV (Um = 1,2 kV) up to 30 kV (Um = 36 kV) : Part 2: cables for rated voltages from 6 kV (Um = 7,2 kV) up to 30 kV (Um = 36 kV)

Active Commuting among K-12 Educators: A Study Examining Walking and Biking to Work

OpenAIRE

Bopp, Melissa; Hastmann, Tanis J.; Norton, Alyssa N.

2013-01-01

Background. Walking and biking to work, active commuting (AC) is associated with many health benefits, though rates of AC remain low in the US. K-12 educators represent a significant portion of the workforce, and employee health and associated costs may have significant economic impact. Therefore, the purpose of this study was to examine the current rates of AC and factors associated with AC among K-12 educators. Methods. A volunteer sample of K-12 educators (n = 437) was recruited to partici...

California's K-12 Public Schools. How Are They Doing?

National Research Council Canada - National Science Library

Carroll, Stephen J; Krop, Cathy; Arkes, Jeremy; Morrison, Peter A; Flanagan, Ann

2005-01-01

... are no longer performing as well as they did previously or as well as schools in other states. The primary objective of our study was to look closely at California's public system of kindergarten through twelfth grade (K-12...

Development of an Attitude Scale to Assess K-12 Teachers' Attitudes toward Nanotechnology

Science.gov (United States)

Lan, Yu-Ling

2012-01-01

To maximize the contributions of nanotechnology to this society, at least 60 countries have put efforts into this field. In Taiwan, a government-funded K-12 Nanotechnology Programme was established to train K-12 teachers with adequate nanotechnology literacy to foster the next generation of Taiwanese people with sufficient knowledge in…

K Basin sludge dissolution engineering study

International Nuclear Information System (INIS)

Westra, A.G.

1998-01-01

The purpose of this engineering study is to investigate the available technology related to dissolution of the K Basin sludge in nitric acid. The conclusion of this study along with laboratory and hot cell tests with actual sludge samples will provide the basis for beginning conceptual design of the sludge dissolver. The K Basin sludge contains uranium oxides, fragments of metallic U, and some U hydride as well as ferric oxyhydroxide, aluminum oxides and hydroxides, windblown sand that infiltrated the basin enclosure, ion exchange resin, and miscellaneous materials. The decision has been made to dispose of this sludge separate from the fuel elements stored in the basins. The sludge will be conditioned so that it meets Tank Waste Remediation System waste acceptance criteria and can be sent to one of the underground storage tanks. Sludge conditioning will be done by dissolving the fuel constituents in nitric acid, separating the insoluble material, adding neutron absorbers for criticality safety, and then reacting the solution with caustic to co-precipitate the uranium and plutonium. There will be five distinct feed streams to the sludge conditioning process two from the K East (KE) Basin and three from the K West (KW) Basin. The composition of the floor and pit sludges which contain more iron oxides and sand than uranium is much different than the canister sludges which are composed of mostly uranium oxides. The sludge conditioning equipment will be designed to process all of the sludge streams, but some of the operating parameters will be adjusted as necessary to handle the different sludge stream compositions. The volume of chemical additions and the amount of undissolved solids will be much different for floor and pit sludge than for canister sludge. Dissolution of uranium metal and uranium dioxide has been studied quite thoroughly and much information is available. Both uranium metal and uranium dioxide have been dissolved on a large scale in nuclear fuel

Exploring Arizona K-12 Virtual Educator Experiences and Perspectives Developing Collaborative Learning Communities

Science.gov (United States)

Cross, Deborah Iyron

2015-01-01

Arizona Online Instruction (AOI) provided an instructional alternative to nearly fifty thousand K-12 students in Arizona during the 2012-2013 school year. Growth in online education underscores the importance of evolving the role of the K-12 virtual teacher as the human agent (Turvey, 2008) demonstrating social learning theory (Bandura, 1977) by…

The lon gene and photoprotection in Escherichia coli K-12

International Nuclear Information System (INIS)

Waksman, G.; Thomas, G.; Favre, A.

1984-01-01

Photoprotection, i.e. the increased resistance of the cells preilluminated with near ultraviolet light (300-380 nm) to the lethal action of 254nm radiations requires either an integrated prophage or a recA mutation in Escherichia coli K12 strains. Significant photoprotection occurs in an Escherichia coli K12 recA + cell containing the lon allele responsible for filamentous growth after 254nm irradiation. The Fil phenotype can be suppressed by the sfiA or sfiB suppressor genes. Since the E. coli K12 recA + lon sfiB strain exhibits no more photoprotection, it is concluded that in lon strains photoprotection is due to the abolition of the 254nm induced filamentation by the near ultraviolet treatment. In addition, near ultraviolet illumination of the cells leads to a severe restriction of the bulk protein synthesis. This effect is observed only in nuv + cells that contain 4-thiouridine the chromophore responsible for photoprotection. It is proposed that in lon (lysogenic strains) photoprotection is due to prevention of the SOS response. During the growth lag, the low residual level of protein synthesis does not allow the induction of the SOS response and accordingly prevents filamentation (the lytic cycle). (author)

CP violation and ΔI=1/2 enhancement in K decays

International Nuclear Information System (INIS)

Choudhury, S.R.; Scadron, M.D.

1996-01-01

We study CP-conserving and CP-violating K 0 →ππ and K 0 →ππγ decays, using the same techniques which explain the ΔI=1/2 enhancement of the former to also explore CP violation of the latter transitions. If CP violation is driven by the WWγ vertex, we show that direct CP violation in K L →ππγ is scaled to the s→dγ E1 quark transition and the latter is suppressed by the GIM mechanism (compatible with recent experiments). In the same spirit, the dominant ΔI=1/2 enhancement of CP-conserving kaon weak decays can be scaled to an s→d quark transition which is enhanced by the GIM mechanism. copyright 1996 The American Physical Society

Perspectives on...Special Collections at ARL Libraries and K-12 Outreach: Current Trends

Science.gov (United States)

Visser, Michelle

2006-01-01

This article examines the results of a survey sent to Association of Research Libraries (ARL) Special Collections requesting information on outreach to K-12 students. Over half of the respondents work with K-12 and many of those who currently do not are planning to. New pressures and changing philosophies contribute to this trend.

K-12 Teacher Perceptions Regarding the Flipped Classroom Model for Teaching and Learning

Science.gov (United States)

Gough, Evan; DeJong, David; Grundmeyer, Trent; Baron, Mark

2017-01-01

A great deal of evidence can be cited from higher education literature on the effectiveness of the flipped classroom; however, very little research was discovered on the flipped classroom at the K-12 level. This study examined K-12 teachers' perceptions regarding the flipped classroom and differences in teachers' perceptions based on grade level…

The influence of excess K2O on the electrical properties of (K,Na)1/2Bi1/2TiO3 ceramics

Science.gov (United States)

Li, Linhao; Li, Ming; Sinclair, Derek C.

2018-04-01

The solid solution (KxNa0.50-x)Bi0.50TiO3 (KNBT) between Na1/2Bi1/2TiO3 and K1/2Bi1/2TiO3 (KBT) has been extensively researched as a candidate lead-free piezoelectric material because of its relatively high Curie temperature and good piezoelectric properties, especially near the morphotropic phase boundary (MPB) at x ˜ 0.10 (20 mol. % KBT). Here, we show that low levels of excess K2O in the starting compositions, i.e., (Ky+0.03Na0.50-y)Bi0.50TiO3.015 (y-series), can significantly change the conduction mechanism and electrical properties compared to a nominally stoichiometric KNBT series (KxNa0.50-x)Bi0.50TiO3 (x-series). Impedance spectroscopy measurements reveal significantly higher bulk conductivity (σb) values for y ≥ 0.10 samples [activation energy (Ea) ≤ 0.95 eV] compared to the corresponding x-series samples which possess bandgap type electronic conduction (Ea ˜ 1.26-1.85 eV). The largest difference in electrical properties occurs close to the MPB composition (20 mol. % KBT) where y = 0.10 ceramics possess σb (at 300 °C) that is 4 orders of magnitude higher than that of x = 0.10 and the oxide-ion transport number in the former is ˜0.70-0.75 compared to processing. This demonstrates the electrical properties of KNBT to be sensitive to low levels of A-site nonstoichiometry and indicates that excess K2O in KNBT starting compositions to compensate for volatilisation can lead to undesirable high dielectric loss and leakage currents at elevated temperatures.

Matrix metalloproteinase 12 is induced by heterogeneous nuclear ribonucleoprotein K and promotes migration and invasion in nasopharyngeal carcinoma

International Nuclear Information System (INIS)

Chung, I-Che; Li, Hsin-Pai; Chang, Yu-Sun; Chen, Lih-Chyang; Chung, An-Ko; Chao, Mei; Huang, Hsin-Yi; Hsueh, Chuen; Tsang, Ngan-Ming; Chang, Kai-Ping; Liang, Ying

2014-01-01

Overexpression of heterogeneous nuclear ribonucleoprotein K (hnRNP K), a DNA/RNA binding protein, is associated with metastasis in nasopharyngeal carcinoma (NPC). However, the mechanisms underlying hnRNP K-mediated metastasis is unclear. The aim of the present study was to determine the role of matrix metalloproteinase (MMP) in hnRNP K-mediated metastasis in NPC. We studied hnRNP K-regulated MMPs by analyzing the expression profiles of MMP family genes in NPC tissues and hnRNP K-knockdown NPC cells using Affymetrix microarray analysis and quantitative RT-PCR. The association of hnRNP K and MMP12 expression in 82 clinically proven NPC cases was determined by immunohistochemical analysis. The hnRNP K-mediated MMP12 regulation was determined by zymography and Western blot, as well as by promoter, DNA pull-down and chromatin immunoprecipitation (ChIP) assays. The functional role of MMP12 in cell migration and invasion was demonstrated by MMP12-knockdown and the treatment of MMP12-specific inhibitor, PF-356231. MMP12 was overexpressed in NPC tissues, and this high level of expression was significantly correlated with high-level expression of hnRNP K (P = 0.026). The levels of mRNA, protein and enzyme activity of MMP12 were reduced in hnRNP K-knockdown NPC cells. HnRNP K interacting with the region spanning −42 to −33 bp of the transcription start site triggered transcriptional activation of the MMP12 promoter. Furthermore, inhibiting MMP12 by MMP12 knockdown and MMP12-specific inhibitor, PF-356231, significantly reduced the migration and invasion of NPC cells. Overexpression of MMP12 was significantly correlated with hnRNP K in NPC tissues. HnRNP K can induce MMP12 expression and enzyme activity through activating MMP12 promoter, which promotes cell migration and invasion in NPC cells. In vitro experiments suggest that NPC metastasis with high MMP12 expression may be treated with PF-356231. HnRNP K and MMP12 may be potential therapeutic markers for NPC, but

Data summary of municipal solid waste management alternatives. Volume 11, Alphabetically indexed bibliography

Energy Technology Data Exchange (ETDEWEB)

None

1992-10-01

This appendix contains the alphabetically indexed bibliography for the complete group of reports on municipal waste management alternatives. The references are listed for each of the following topics: mass burn technologies, RDF technologies, fluidized-bed combustion, pyrolysis and gasification of MSW, materials recovery- recycling technologies, sanitary landfills, composting, and anaerobic digestion of MSW.

Neutron inelastic sattering from liquid 3He at 40 mK and at 1.2 K

International Nuclear Information System (INIS)

Skoeld, K.; Pelizzari, C.A.

1978-01-01

In a previous neutron scattering experiment on 3 He at T = 15 mK the present authors observed two peaks in the scattering function which were identified as the zero sound mode and the spin-fluctuation peak respectively. These results are different from those obtained by others at T = 0.63 K in which case no such structure was observed. In order to determine whether this discrepancy is due to the difference in the temperature of the two experiments, measurements have now been made at T = 40 mK and at T = 1.2 K. These results show that the two-peak structure persists at the higher temperature although measurable broadening is observed in the spin-fluctuation part of the spectrum. (author)

Virtual Schools: The Changing Landscape of K-12 Education in the U.S.

Science.gov (United States)

Toppin, Ian N.; Toppin, Sheila M.

2016-01-01

Virtual schools are a growing phenomenon in k-12 education. School systems in almost every state in the United States offer some version of fully online or blended education. It is no longer far-fetched to conclude that if the current trend continues, virtual school enrollments will eclipse those of traditional brick-and-mortar k-12 institutions…

Viewing speech in action: speech articulation videos in the public domain that demonstrate the sounds of the International Phonetic Alphabet (IPA)

OpenAIRE

Nakai, S.; Beavan, D.; Lawson, E.; Leplâtre, G.; Scobbie, J. M.; Stuart-Smith, J.

2016-01-01

In this article, we introduce recently released, publicly available resources, which allow users to watch videos of hidden articulators (e.g. the tongue) during the production of various types of sounds found in the world’s languages. The articulation videos on these resources are linked to a clickable International Phonetic Alphabet chart ([International Phonetic Association. 1999. Handbook of the International Phonetic Association: A Guide to the Use of the International Phonetic Alphabet. ...

Leadership Analysis in K-12 Case Study: "Divided Loyalties"

Science.gov (United States)

Alsubaie, Merfat Ayesh

2016-01-01

This report mainly aims to provide a critical and in-depth analysis of the K-12 Case, "Divided Loyalty" by Holy and Tartar (2004). The case recounts how the manifestation of inadequate leadership skills in a school setting could affect negatively the performance of students.

Information Security Management Practices of K-12 School Districts

Science.gov (United States)

Nyachwaya, Samson

2013-01-01

The research problem addressed in this quantitative correlational study was the inadequacy of sound information security management (ISM) practices in K-12 school districts, despite their increasing ownership of information assets. Researchers have linked organizational and sociotechnical factors to the implementation of information security…

PERENCANAAN PEMANFAATAN MARINE FUEL OIL (MFO SEBAGAI BAHAN BAKAR ENGINE DIESEL MaK

Directory of Open Access Journals (Sweden)

Hendra Poeswanto

2015-06-01

Full Text Available PT. PLN (Persero Area Bontang tengah berupaya melakukan penggantian jenis bahan bakar pada engine diesel merk MaK yang semula menggunakan High Speed Diesel (HSD menjadi Marine Fuel Oil (MFO. Tujuan penelitian ini untuk mengetahui proses treatment bahan bakar MFO untuk menurunkan viscositas dan penyeragaman ukuran partikel bahan bakar pada engine diesel merk MaK dan mengetahui perbandingan biaya penghematan dan evisiensi pemakaian bahan bakar HSD dengan bahan bakar MFO. Metode yang digunakan analisa perpindaahan panas pada oil heater dan viskositas bahan bakar yang digunakan untuk menentukan proses treatment bahan bakar MFO. Dari hasil perencanaan, proses treatment menggunakan oli heater dimana proses pemanasan oli dengan memanfaatkan panas dari gas buang hasil pembakaran. Dengan penggunaan bahan bakar MFO dapat menghemat biaya konsumsi bahan bakar sebesar Rp. 21.827.520,- per harinya.

Engineering Encounters: Can a Student Really Do What Engineers Do?

Science.gov (United States)

Brown, Sherri; Newman, Channa; Dearing-Smith, Kelley; Smith, Stephanie

2014-01-01

"Framework for K-12 Science Education" states that "children are natural engineers … they spontaneously build sand castles, dollhouses, and hamster enclosures and use a variety of tools and materials for their own playful purposes" (NRC 2012, p. 70). The "Next Generation Science Standards" ("NGSS") also…

Nanodomain Engineered (K, Na)NbO3 Lead-Free Piezoceramics: Enhanced Thermal and Cycling Reliabilities

DEFF Research Database (Denmark)

Yao, Fang-Zhou; Wang, Ke; Cheng, Li-Qian

2015-01-01

- based materials, accepting the drawbacks of high temperature and cycling instabilities. Here, we present that CaZrO3-modified (K, Na)NbO3 piezoceramics not only possess excellent performance at ambient conditions benefiting from nanodomain engineering, but also exhibit superior stability against......The growing environmental concerns have been pushing the development of viable green alternatives for lead-based piezoceramics to be one of the priorities in functional ceramic materials. A polymorphic phase transition has been utilized to enhance piezoelectric properties of lead-free (K, Na)NbO3...... temperature fluctuation and electrical fatigue cycling. It was found that the piezoelectric coefficient d33 is temperature independent under 4 kV/mm, which can be attributed to enhanced thermal stability of electric field engineered domain configuration; whereas the electric field induced strain exhibits...

Illegal alphabets and adult biliteracy latino migrants crossing the linguistic border, expanded edition

CERN Document Server

Kalmar, Tomás Mario

2015-01-01

How do "illegal aliens" chart the speech sounds of colloquial English? This book is timeless in offering an unusually direct entry into how a group of Mexican fruit pickers analyze their first encounter with local American speech in a tiny rural Midwestern community in the United States. Readers see close up how intelligently migrant workers help each other use what they already know-the alphabetic principle of one letter, one sound-to teach each other, from scratch, at the very first contact, a language which none of them can speak. They see how and why the strategies adult immigrants actually use in order to cope with English in the real world seem to have little in common with those used in publicly funded bilingual and ESL classrooms. What's new in this expanded edition of Tomás Mario Kalmar's landmark Illegal Alphabets and Adult Biliteracy are in-depth commentaries from six distinguished scholars-Peter Elbow, Ofelia García, James Paul Gee, Hervé Varenne, Luis Vázquez León, Karen Velasquez-who bring ...

MAIN-BELT ASTEROIDS IN THE K2 ENGINEERING FIELD OF VIEW

International Nuclear Information System (INIS)

Szabó, R.; Sárneczky, K.; Szabó, Gy. M.; Pál, A.; Kiss, Cs. P.; Kiss, L. L.; Csák, B.; Illés, L.; Rácz, G.

2015-01-01

Unlike NASA’s original Kepler Discovery Mission, the renewed K2 Mission will target the plane of the Ecliptic, observing each field for approximately 75 days. This will bring new opportunities and challenges, in particular the presence of a large number of main-belt asteroids that will contaminate the photometry. The large pixel size makes K2 data susceptible to the effects of apparent minor planet encounters. Here, we investigate the effects of asteroid encounters on photometric precision using a subsample of the K2 engineering data taken in 2014 February. We show examples of asteroid contamination to facilitate their recognition and distinguish these events from other error sources. We conclude that main-belt asteroids will have considerable effects on K2 photometry of a large number of photometric targets during the Mission that will have to be taken into account. These results will be readily applicable for future space photometric missions applying large-format CCDs, such as TESS and PLATO

MAIN-BELT ASTEROIDS IN THE K2 ENGINEERING FIELD OF VIEW

Energy Technology Data Exchange (ETDEWEB)

Szabó, R.; Sárneczky, K.; Szabó, Gy. M.; Pál, A.; Kiss, Cs. P.; Kiss, L. L. [Konkoly Observatory, Research Centre for Astronomy and Earth Sciences, Hungarian Academy of Sciences, H-1121 Budapest, Konkoly Thege Miklós út 15-17 (Hungary); Csák, B. [Gothard-Lendület Research Team, H-9704 Szombathely, Szent Imre herceg út 112 (Hungary); Illés, L.; Rácz, G., E-mail: rszabo@konkoly.hu [Eötvös Loránd Tudományegyetem, H-1117 Pázmány Péter sétány 1/A, Budapest (Hungary)

2015-03-15

Unlike NASA’s original Kepler Discovery Mission, the renewed K2 Mission will target the plane of the Ecliptic, observing each field for approximately 75 days. This will bring new opportunities and challenges, in particular the presence of a large number of main-belt asteroids that will contaminate the photometry. The large pixel size makes K2 data susceptible to the effects of apparent minor planet encounters. Here, we investigate the effects of asteroid encounters on photometric precision using a subsample of the K2 engineering data taken in 2014 February. We show examples of asteroid contamination to facilitate their recognition and distinguish these events from other error sources. We conclude that main-belt asteroids will have considerable effects on K2 photometry of a large number of photometric targets during the Mission that will have to be taken into account. These results will be readily applicable for future space photometric missions applying large-format CCDs, such as TESS and PLATO.

1:12,000 Grid of Louisiana, Geographic NAD83, LGS (2007) [quad12k_losco_2007

Data.gov (United States)

Louisiana Geographic Information Center — This "QUAD12K_LOSCO_2007" ploygon shapefile is a reference index to the polygon footprints of Digital Orthographic Quarter Quadrangles (DOQQs) for Louisiana and a...

Promoting Alphabet Knowledge Using Peer-Mediated Intervention: A Dynamic Duo for Early Literacy Development

Science.gov (United States)

Harris, Kathleen I.; Kinley, Hannah L.; Cook, Angela

2017-01-01

One of early childhood teachers' first questions of parents with regard to school readiness is whether the child knows the ABCs (Hyson & Tomlinson, 2014). Crucial pre-reading and writing skills, such as oral language, phonological awareness, print awareness, and alphabet letter recognition, are important to children's cognitive development…

YES 2K6: A mentorship program for young engineers and scientists

Science.gov (United States)

Boice, D. C.; Asbell, H. E.

The Young Engineers and Scientists 2006 YES 2K6 Program is a community partnership between Southwest Research Institute SwRI and local high schools in San Antonio Texas USA YES has been highly successful during the past 14 years and YES 2K6 continues this trend This program provides talented high school juniors and seniors a bridge between classroom instruction and real world research experiences in physical sciences including space science and astronomy and engineering YES 2K6 consists of two parts 1 an intensive three-week summer workshop held at SwRI where students experience the research environment first-hand develop skills and acquire tools for solving scientific problems attend mini-courses and seminars on electronics computers and the Internet careers science ethics and other topics and select individual research projects to be completed during the academic year and 2 a collegial mentorship where students complete individual research projects under the guidance of their mentors during the academic year and earn honors credit At the end of the school year students publicly present and display their work acknowledging their accomplishments and spreading career awareness to other students and teachers YES 2K6 developed a website for the Magnetospheric Multiscale Mission MMS from the perspective of high school students Over the past 14 years all YES graduates have entered college several have worked for SwRI and three scientific publications have resulted Student evaluations indicate the effectiveness of YES on

Are recent cohorts of women with engineering bachelors less likely to stay in engineering?

Directory of Open Access Journals (Sweden)

Shulamit eKahn

2015-08-01

Full Text Available Women are an increasing percentage of Bachelors in Engineering (BSEs graduates – rising from 1% in 1970 to 20% in the 2000s – encouraged by increasing K-12 emphasis on attracting girls to STEM and efforts to incorporate engineering and technology into K-12 curricula. Retention of women in STEM and in engineering in particular has been a concern historically. In this paper, we investigate whether this gap has increased because a larger proportion of females entering engineering find themselves ill-matched to this field, or whether the gap has decreased as engineering becomes more accommodating to women. Using 1993 - 2010 nationally representative NSF SESTAT surveys, we compare cohorts of BSEs at the same early-career stages (from 1-2 years to 7-8 years post-bachelors. We find no evidence of a time trend in the gender gap in retention in engineering and a slightly decreasing gender gap in leaving the labor force. We find, as others have, that the majority of the gender retention gap is due to women leaving the labor force entirely and that this exit is highly correlated with child-bearing; yet women with engineering majors are half as likely as all college-educated women to leave the labor market. There are no clear time trends in female BSEs leaving the labor market. Single childless women are actually more likely than men to remain in engineering jobs. Some gender differences in retention others found are caused by differences in race and engineering subfield. With controls for these, there is no gender retention difference by 7-8 years post-bachelors for those full-time employed. There were two usual cohorts – women with 1991-1994 BSEs were particularly likely to remain in engineering and women with 1998-2001 BSEs were particularly likely to leave engineering, compared to men. Cohorts before and after these revert towards the mean, indicating no time trend. Also, women who leave engineering are just as likely as men to stay in math

Are recent cohorts of women with engineering bachelors less likely to stay in engineering?

Science.gov (United States)

Kahn, Shulamit; Ginther, Donna K

2015-01-01

Women are an increasing percentage of Bachelors in Engineering (BSEs) graduates-rising from 1% in 1970 to 20% in the 2000s-encouraged by increasing K-12 emphasis on attracting girls to STEM and efforts to incorporate engineering and technology into K-12 curricula. Retention of women in STEM and in engineering in particular has been a concern historically. In this paper, we investigate whether this gap has increased because a larger proportion of females entering engineering find themselves ill-matched to this field, or whether the gap has decreased as engineering becomes more accommodating to women. Using 1993-2010 nationally representative NSF SESTAT surveys, we compare cohorts of BSEs at the same early-career stages (from 1-2 to 7-8 years post-bachelors). We find no evidence of a time trend in the gender gap in retention in engineering and a slightly decreasing gender gap in leaving the labor force. We find, as others have, that the majority of the gender retention gap is due to women leaving the labor force entirely and that this exit is highly correlated with child-bearing; yet women with engineering majors are half as likely as all college-educated women to leave the labor market. There are no clear time trends in female BSEs leaving the labor market. Single childless women are actually more likely than men to remain in engineering jobs. Some of the gender differences in retention we find are caused by differences in race and engineering subfield. With controls for these, there is no gender retention difference by 7-8 years post-bachelors for those full-time employed. There were two unusual cohorts-women with 1991-1994 BSEs were particularly likely to remain in engineering and women with 1998-2001 BSEs were particularly likely to leave engineering, compared to men. Cohorts before and after these revert toward the mean, indicating no time trend. Also, women who leave engineering are just as likely as men to stay in math-intensive STEM jobs.

Development and Engineering Design in Support of "Rover Ranch": A K-12 Outreach Software Project

Science.gov (United States)

Pascali, Raresh

2003-01-01

A continuation of the initial development started in the summer of 1999, the body of work performed in support of 'ROVer Ranch' Project during the present fellowship dealt with the concrete concept implementation and resolution of the related issues. The original work performed last summer focused on the initial examination and articulation of the concept treatment strategy, audience and market analysis for the learning technologies software. The presented work focused on finalizing the set of parts to be made available for building an AERCam Sprint type robot and on defining, testing and implementing process necessary to convert the design engineering files to VRML files. Through reverse engineering, an initial set of mission critical systems was designed for beta testing in schools. The files were created in ProEngineer, exported to VRML 1.0 and converted to VRML 97 (VRML 2.0) for final integration in the software. Attributes for each part were assigned using an in-house developed JAVA based program. The final set of attributes for each system, their mutual interaction and the identification of the relevant ones to be tracked, still remain to be decided.

Zero Energy Schools: Designing for the Future: Zero Energy Ready K-12 Schools

Energy Technology Data Exchange (ETDEWEB)

Torcellini, Paul A [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

2017-09-29

Designing, building, and operating zero energy ready K-12 schools provides benefits for districts, students, and teachers. Optimizing energy efficiency is important in any building, but it's particularly important in K-12 schools. Many U.S. school districts struggle for funding, and improving a school building's energy efficiency can free up operational funds that may then be available for educational and other purposes.

Spacemakers: A Leadership Perspective on Curriculum and the Purpose of K-12 Educational Makerspaces

Science.gov (United States)

Harron, Jason R.; Hughes, Joan E.

2018-01-01

This qualitative research study investigated how educational makerspace leaders, whom we refer to as spacemakers, framed the purpose of the makerspace in K-12 education and how makerspaces support school curriculum. Using interviews with twelve K-12 spacemakers, the study found spacemakers were experienced, self-motivated educators. These leaders…

Physiology of SLC12 transporters: lessons from inherited human genetic mutations and genetically engineered mouse knockouts.

Science.gov (United States)

Gagnon, Kenneth B; Delpire, Eric

2013-04-15

Among the over 300 members of the solute carrier (SLC) group of integral plasma membrane transport proteins are the nine electroneutral cation-chloride cotransporters belonging to the SLC12 gene family. Seven of these transporters have been functionally described as coupling the electrically silent movement of chloride with sodium and/or potassium. Although in silico analysis has identified two additional SLC12 family members, no physiological role has been ascribed to the proteins encoded by either the SLC12A8 or the SLC12A9 genes. Evolutionary conservation of this gene family from protists to humans confirms their importance. A wealth of physiological, immunohistochemical, and biochemical studies have revealed a great deal of information regarding the importance of this gene family to human health and disease. The sequencing of the human genome has provided investigators with the capability to link several human diseases with mutations in the genes encoding these plasma membrane proteins. The availability of bacterial artificial chromosomes, recombination engineering techniques, and the mouse genome sequence has simplified the creation of targeting constructs to manipulate the expression/function of these cation-chloride cotransporters in the mouse in an attempt to recapitulate some of these human pathologies. This review will summarize the three human disorders that have been linked to the mutation/dysfunction of the Na-Cl, Na-K-2Cl, and K-Cl cotransporters (i.e., Bartter's, Gitleman's, and Andermann's syndromes), examine some additional pathologies arising from genetically modified mouse models of these cotransporters including deafness, blood pressure, hyperexcitability, and epithelial transport deficit phenotypes.

The K-12 Educational Technology Value Chain: Apps for Kids, Tools for Teachers and Levers for Reform

Science.gov (United States)

Pierce, Glenn L.; Cleary, Paul F.

2016-01-01

Historically implementing, maintaining and managing educational technology has been difficult for K-12 educational systems. Consequently, opportunities for significant advances in K-12 education have often gone unrealized. With the maturation of Internet delivered services along with K-12 institutional trends, educational technologies are poised…

Iterative and non-iterative solutions of engine flows using ASM and k-ε turbulence models

International Nuclear Information System (INIS)

Khaleghi, H.; Fallah, E.

2003-01-01

Various turbulent models are widely developed in order to make a good prediction of turbulence phenomena in different applications. The standard k-ε model shows a poor prediction for some applications. The Reynolds Stress Model (RSM) is expected to give a better prediction of turbulent characteristics, because a separate differential equation for each Reynolds stress component is solved in this model. In order to save both time and memory in this calculation a new Algebraic Stress Model (ASM) which was developed by Lumly et al in 1995 is used for calculations of flow characteristics in the internal combustion engine chamber. With using turbulent realizability principles, this model becomes a powerful and reliable turbulence model. In this paper the abilities of the model is examined in internal combustion engine flows. The results of ASM and k-ε models are compared with the experimental data. It is shown that the poor predictions of k-ε model are modified by ASM model. Also in this paper non-iterative PISO and iterative SIMPLE solution algorithms are compared. The results show that the PISO solution algorithm is the preferred and more efficient procedure in the calculation of internal combustion engine. (author)

Tablets in K-12 Education: Integrated Experiences and Implications

Science.gov (United States)

An, Heejung, Ed.; Alon, Sandra, Ed.; Fuentes, David, Ed.

2015-01-01

The inclusion of new and emerging technologies in the education sector has been a topic of interest to researchers, educators, and software developers alike in recent years. Utilizing the proper tools in a classroom setting is a critical factor in student success. "Tablets in K-12 Education: Integrated Experiences and Implications"…

The Humanistic Side of Engineering: Considering Social Science and Humanities Dimensions of Engineering in Education and Research

Science.gov (United States)

Hynes, Morgan; Swenson, Jessica

2013-01-01

Mathematics and science knowledge/skills are most commonly associated with engineering's pre-requisite knowledge. Our goals in this paper are to argue for a more systematic inclusion of social science and humanities knowledge in the introduction of engineering to K-12 students. As part of this argument, we present a construct for framing the…

Disorder effects in Mn(12)-acetate at 83 K.

Science.gov (United States)

Cornia, Andrea; Fabretti, Antonio Costantino; Sessoli, Roberta; Sorace, Lorenzo; Gatteschi, Dante; Barra, Anne-Laure; Daiguebonne, Carole; Roisnel, Thierry

2002-07-01

The structure of hexadeca-mu-acetato-tetraaquadodeca-mu(3)-oxo-dodecamanganese bis(acetic acid) tetrahydrate, [Mn(12)O(12)(CH(3)COO)(16)(H(2)O)(4)] x 2CH(3)COOH x 4H(2)O, known as Mn(12)-acetate, has been determined at 83 (2) K by X-ray diffraction methods. The fourfold (S(4)) molecular symmetry is disrupted by a strong hydrogen-bonding interaction with the disordered acetic acid molecule of solvation, which displaces one of the acetate ligands in the cluster. Up to six Mn(12) isomers are potentially present in the crystal lattice, which differ in the number and arrangement of hydrogen-bonded acetic acid molecules. These results considerably improve the structural information available on this molecular nanomagnet, which was first synthesized and characterized by Lis [Acta Cryst. (1980), B36, 2042-2046].

Comparison of alphabetical versus categorical display format for medication order entry in a simulated touch screen anesthesia information management system: an experiment in clinician-computer interaction in anesthesia

Directory of Open Access Journals (Sweden)

Marian Anil A

2012-05-01

Full Text Available Abstract Background Anesthesia information management system (AIMS records should be designed and configured to facilitate the accurate and prompt recording of multiple drugs administered coincidentally or in rapid succession. Methods We proposed two touch-screen display formats for use with our department’s new EPIC touch-screen AIMS. In one format, medication “buttons” were arranged in alphabetical order (i.e. A-C, D-H etc.. In the other, buttons were arranged in categories (Common, Fluids, Cardiovascular, Coagulation etc.. Both formats were modeled on an iPad screen to resemble the AIMS interface. Anesthesia residents, anesthesiologists, and Certified Registered Nurse Anesthetists (n = 60 were then asked to find and touch the correct buttons for a series of medications whose names were displayed to the side of the entry screen. The number of entries made within 2 minutes was recorded. This was done 3 times for each format, with the 1st format chosen randomly. Data were analyzed from the third trials with each format to minimize differences in learning. Results The categorical format had a mean of 5.6 more drugs entered using the categorical method in two minutes than the alphabetical format (95% confidence interval [CI] 4.5 to 6.8, P  Conclusions The use of touch-screen user interfaces in healthcare is increasingly common. Arrangement of drugs names in a categorical display format in the medication order-entry touch screen of an AIMS can result in faster data entry compared to an alphabetical arrangement of drugs. Results of this quality improvement project were used in our department’s design of our final intraoperative electronic anesthesia record. This testing approach using cognitive and usability engineering methods can be used to objectively design and evaluate many aspects of the clinician-computer interaction in electronic health records.

Stirling Space Engine Program. Volume 1; Final Report

Science.gov (United States)

Dhar, Manmohan

1999-01-01

The objective of this program was to develop the technology necessary for operating Stirling power converters in a space environment and to demonstrate this technology in full-scale engine tests. Hardware development focused on the Component Test Power Converter (CTPC), a single cylinder, 12.5-kWe engine. Design parameters for the CTPC were 150 bar operating pressure, 70 Hz frequency, and hot-and cold-end temperatures of 1050 K and 525 K, respectively. The CTPC was also designed for integration with an annular sodium heat pipe at the hot end, which incorporated a unique "Starfish" heater head that eliminated highly stressed brazed or weld joints exposed to liquid metal and used a shaped-tubed electrochemical milling process to achieve precise positional tolerances. Selection of materials that could withstand high operating temperatures with long life were another focus. Significant progress was made in the heater head (Udimet 700 and Inconel 718 and a sodium-filled heat pipe); the alternator (polyimide-coated wire with polyimide adhesive between turns and a polyimide-impregnated fiberglass overwrap and samarium cobalt magnets); and the hydrostatic gas bearings (carbon graphite and aluminum oxide for wear couple surfaces). Tests on the CTPC were performed in three phases: cold end testing (525 K), engine testing with slot radiant heaters, and integrated heat pipe engine system testing. Each test phase was successful, with the integrated engine system demonstrating a power level of 12.5 kWe and an overall efficiency of 22 percent in its maiden test. A 1500-hour endurance test was then successfully completed. These results indicate the significant achievements made by this program that demonstrate the viability of Stirling engine technology for space applications.

Physical Education Teacher Educator's Perceptions toward and Understanding of K-12 Online Physical Education

Science.gov (United States)

Daum, David N.; Woods, Amelia M.

2015-01-01

K-12 online physical education (OLPE) is as an educational opportunity in at least 30 states in the US (NASPE, 2006; 2010; 2012). The purpose of this study was to examine physical education teacher educators' perceptions toward and understanding of K-12 OLPE. Bandura's Social Cognitive Theory (1986) served as the theoretical framework for this…

Role of Public Outreach in the University Science Mission: Publishing K-12 Curriculum, Organizing Tours, and Other Methods of Engagement

Science.gov (United States)

Dittrich, T. M.

2015-12-01

Much attention has been devoted in recent years to the importance of Science, Technology, Engineering, and Math (STEM) education in K-12 curriculum for developing a capable workforce. Equally important is the role of the voting public in understanding STEM-related issues that impact public policy debates such as the potential impacts of climate change, hydraulic fracturing in oil and gas exploration, mining impacts on water quality, and science funding. Since voted officials have a major impact on the future of these policies, it is imperative that the general public have an understanding of the basic science behind these issues. By engaging with the public in a more fundamental way, university students can play an important role in educating the public while at the same time enhancing their communication skills and gaining valuable teaching experience. I will talk about my own experiences in (1) evaluating and publishing water chemistry and hazardous waste cleanup curriculum on the K-12 engineering platform TeachEngineering.org, (2) organizing public tours of water and energy sites (e.g., abandoned mine sites, coal power plants, wastewater treatment plants, hazardous waste treatment facilities), and (3) other outreach and communication activities including public education of environmental issues through consultations with customers of a landscaping/lawn mowing company. The main focus of this presentation will be the role that graduate students can play in engaging and educating their local community and lessons learned from community projects (Dittrich, 2014; 2012; 2011). References: Dittrich, T.M. 2014. Adventures in STEM: Lessons in water chemistry from elementary school to graduate school. Abstract ED13E-07 presented at 2014 Fall Meeting, AGU, San Francisco, Calif., 15-19 Dec. Dittrich, T.M. 2012. Collaboration between environmental water chemistry students and hazardous waste treatment specialists on the University of Colorado-Boulder campus. Abstract ED53C

Engineering Encounters: The Cat in the Hat Builds Satellites. A Unit Promoting Scientific Literacy and the Engineering Design Process

Science.gov (United States)

Rehmat, Abeera P.; Owens, Marissa C.

2016-01-01

This column presents ideas and techniques to enhance your science teaching. This month's issue shares information about a unit promoting scientific literacy and the engineering design process. The integration of engineering with scientific practices in K-12 education can promote creativity, hands-on learning, and an improvement in students'…

Familial Colorectal Cancer: Understanding the Alphabet Soup.

Science.gov (United States)

Giglia, Matthew D; Chu, Daniel I

2016-09-01

While most colorectal cancers (CRCs) originate from nonhereditary spontaneous mutations, one-third of cases are familial or hereditary. Hereditary CRCs, which account for < 5% of all CRCs, have identifiable germline mutations and phenotypes, such as Lynch syndrome and familial adenomatous polyposis (FAP). Familial CRCs, which account for up to 30% of CRCs, have no identifiable germline mutation or specific pattern of inheritance, but higher-than-expected incidence within a family. Since the discovery that certain genotypes can lead to development of CRC, thousands of mutations have now been implicated in CRC. These new findings have enhanced our ability to identify at-risk patients, initiate better surveillance, and take preventative measures. Given the large number of genes now associated with hereditary and familial CRCs, clinicians should be familiar with the alphabet soup of genes to provide the highest quality of care for patients and families.

Collaborative Research: The Alphabetic Braille and Contracted Braille Study as an Example of Collaborative Research

Science.gov (United States)

Wormsley, Diane P.; Emerson, Robert Wall; Erin, Jane

2011-01-01

This article examines the Alphabetic Braille Contracted Braille Study in relation to the dimensions of collaborative research: extent, intensity, substance, heterogeneity, velocity, formality, and productivity. It also discusses the dimensions of financing research and researchers' attitudes. The overall consensus is that the study would not have…

K-12 Marketplace Sees Major Flow of Venture Capital

Science.gov (United States)

Ash, Katie

2012-01-01

The flow of venture capital into the K-12 education market has exploded over the past year, reaching its highest transaction values in a decade in 2011, industry observers say. They attribute that rise to such factors as a heightened interest in educational technology; the decreasing cost of electronic devices such as tablet computers, laptops,…

The Ideological Aspects of Contemporary Cyrillic Alphabet Transliteration Practices in the Balkans

Directory of Open Access Journals (Sweden)

Giustina Selvelli

2016-02-01

Full Text Available This article illustrates the new rules on the transliteration of the Cyrillic alphabet adopted in Bulgaria, Serbia and the Republic of Macedonia over the last few years. It also considers the possible political and identity reasons underlying changes to such practices. To this aim, I contextualize the question within various ongoing debates in the respective countries, with reference to the ideologies that have emerged in the most recent post-socialist period.

CCQM-K11.2 determination of glucose in human serum and CCQM-K12.2 determination of creatinine in human serum

Science.gov (United States)

Wise, Stephen A.; Phinney, Karen W.; Duewer, David L.; Sniegoski, Lorna T.; Welch, Michael J.; Pritchett, Jeanita; Pabello, Guiomar; Avila Calderon, Marco A.; Balderas, Miryan; Qinde, Liu; Kooi, Lee Tong; Rego, Eliane; Garrido, Bruno; Allegri, Gabriella; de La Cruz, Marcia; Barrabin, Juliana; Monteiro, Tânia; Lee, Hwashim; Kim, Byungjoo; Delatour, Vincent; Peignaux, Maryline; Kawaguchi, Migaku; Bei, Xu; Can, Quan; Nammoonnoy, Jintana; Schild, Katrin; Ohlendorf, Rüdiger; Henrion, Andre; Ceyhan Gören, Ahmet; Yılmaz, Hasibe; Bilsel, Mine; Konopelko, L.; Krylov, A.; Lopushanskaya, E.

2018-01-01

Glucose and creatinine are two of the most frequently measured substances in human blood/serum for assessing the health status of individuals. Because of their clinical significance, CCQM-K11 glucose in human serum and CCQM-K12 creatinine in human serum were the fourth and fifth key comparisons (KCs) performed by the Organic Analysis Working Group (OAWG). These KCs were conducted in parallel and were completed in 2001. The initial subsequent KCs for glucose, CCQM-K11.1, and creatinine, CCQM-K12.1, were completed in 2005. Measurements for the next KCs for these two measurands, CCQM-K11.2 and CCQM-K12.2, were completed in 2013. While designed as subsequent KCs, systematic discordances between the participants' and the anchor institution's results in both comparisons lead the OAWG to request reference results from two experienced laboratories that had participated in the 2001 comparisons. Based on the totality of the available information, the OAWG converted both CCQM-K11.2 and CCQM-K12.2 to 'Track C' KCs where the key comparison reference value is estimated by consensus. These comparisons highlighted that carrying out comparisons for complex chemical measurements and expecting to be able to treat them under the approaches used for formal CIPM subsequent comparisons is not an appropriate strategy. The approach used here is a compromise to gain the best value from the comparison; it is not an approach that will be used in the future. Instead, the OAWG will focus on Track A and Track C comparisons that are treated as stand-alone entities. Participation in CCQM-K11.2 demonstrates a laboratory's capabilities to measure a polar (pKow > 2), low molecular mass (100 g/mol to 500 g/mol) metabolite in human serum at relatively high concentrations (0.1 mg/g to 10 mg/g). Participation in CCQM-K12.2 demonstrates capabilities to measure similar classes of metabolites at relatively low concentrations (1 μg/g to 30 μg/g). The capabilities required for the analysis of complex

Integrating Engineering into Delaware's K-5 Classrooms: A Study of Pedagogical and Curricular Resources

Science.gov (United States)

Grusenmeyer, Linda Huey

This study examines the personal and curricular resources available to Delaware's elementary teachers during a time of innovative curriculum change, i.e., their knowledge, goals and beliefs regarding elementary engineering curriculum and the pedagogical support to teach two Science and Engineering Practices provided by science teaching materials. Delaware was at the forefront of K-12 STEM movement, first to adopt statewide elementary curriculum materials to complement existing science units, and one of the first to adopt the new science standards--Next Generation Science Standards. What supports were available to teachers as they adapted and adopted this new curriculum? To investigate this question, I examined (1) teachers' beliefs about engineering and the engineering curriculum, and (2) the pedagogical supports available to teachers in selected science and engineering curriculum. Teachers' knowledge, goals, and beliefs regarding Delaware's adoption of new elementary engineering curriculum were surveyed using an adapted version of the Design, Engineering, and Technology Survey (Hong, Purser, & Gardella, 2011; Yaser, Baker, Carpius, Krauss, & Roberts, 2006). Also, three open ended questions sought to reveal deeper understanding of teacher knowledge and understanding of engineering; their concerns about personal and systemic resources related to the new curriculum, its logistics, and feasibility; and their beliefs about the potential positive impact presented by the engineering education initiative. Teacher concerns were analyzed using the Concerns-Based Adoption Model (Hall & Hord, 2010). Lay understandings of engineering were analyzed by contrasting naive representations of engineering with three key characteristics of engineering adapted from an earlier study (Capobianco Diefes-Dux, Mena, & Weller, 2011). Survey findings for teachers who had attended training and those who have not yet attended professional development in the new curriculum were compared with few

Moving Beyond of The Alphabet Soup of HIV Prevention

Science.gov (United States)

Collins, Chris; Coates, Thomas J.; Curran, James

2010-01-01

It is time to scrap the “ABCs” and elevate the debate on HIV prevention beyond the incessant controversies over individual interventions. The ABCs are a woefully incomplete list of necessary prevention interventions, but the goal should not be to just add more letters to the prevention alphabet. Instead, advancing global HIV prevention means holding national gover nments, donors and global agencies accountable for prevention efforts that are tailored to national epidemics, bring quality interventions to a scale, and address environmental factors in vulnerability. The debate is not so much about one intervention or another, but whether countries have a comprehensive prevention effort in place that responds to their own unique situations. PMID:18641471

Engineering Education in the Science Classroom: A Case Study of One Teacher's Disparate Approach with Ability-Tracked Classrooms

Science.gov (United States)

Schnittka, Christine G.

2012-01-01

Currently, unless a K-12 student elects to enroll in technology-focused schools or classes, exposure to engineering design and habits of mind is minimal. However, the "Framework for K-12 Science Education," published by the National Research Council in 2011, includes engineering design as a new and major component of the science content…

The 25 kWe solar thermal Stirling hydraulic engine system: Conceptual design

Science.gov (United States)

White, Maurice; Emigh, Grant; Noble, Jack; Riggle, Peter; Sorenson, Torvald

1988-01-01

The conceptual design and analysis of a solar thermal free-piston Stirling hydraulic engine system designed to deliver 25 kWe when coupled to a 11 meter test bed concentrator is documented. A manufacturing cost assessment for 10,000 units per year was made. The design meets all program objectives including a 60,000 hr design life, dynamic balancing, fully automated control, more than 33.3 percent overall system efficiency, properly conditioned power, maximum utilization of annualized insolation, and projected production costs. The system incorporates a simple, rugged, reliable pool boiler reflux heat pipe to transfer heat from the solar receiver to the Stirling engine. The free-piston engine produces high pressure hydraulic flow which powers a commercial hydraulic motor that, in turn, drives a commercial rotary induction generator. The Stirling hydraulic engine uses hermetic bellows seals to separate helium working gas from hydraulic fluid which provides hydrodynamic lubrication to all moving parts. Maximum utilization of highly refined, field proven commercial components for electric power generation minimizes development cost and risk.

Active commuting among K-12 educators: a study examining walking and biking to work.

Science.gov (United States)

Bopp, Melissa; Hastmann, Tanis J; Norton, Alyssa N

2013-01-01

Walking and biking to work, active commuting (AC) is associated with many health benefits, though rates of AC remain low in the US. K-12 educators represent a significant portion of the workforce, and employee health and associated costs may have significant economic impact. Therefore, the purpose of this study was to examine the current rates of AC and factors associated with AC among K-12 educators. A volunteer sample of K-12 educators (n = 437) was recruited to participate in an online survey. Participants responded about AC patterns and social ecological influences on AC (individual, interpersonal, institutional, community, and environmental factors). t-tests and ANOVAs examined trends in AC, and Pearson correlations examined the relationship between AC and dependent variables. Multiple regression analysis determined the relative influence of individual, interpersonal, institutional, community, and environmental levels on AC. Participants actively commuted 0.51 ± 1.93 times/week. There were several individual, interpersonal, institutional, community, and environmental factors significantly related to AC. The full model explained 60.8% of the variance in AC behavior. This study provides insight on the factors that determine K-12 educators mode of commute and provide some insight for employee wellness among this population.

Active Commuting among K-12 Educators: A Study Examining Walking and Biking to Work

Directory of Open Access Journals (Sweden)

Melissa Bopp

2013-01-01

Full Text Available Background. Walking and biking to work, active commuting (AC is associated with many health benefits, though rates of AC remain low in the US. K-12 educators represent a significant portion of the workforce, and employee health and associated costs may have significant economic impact. Therefore, the purpose of this study was to examine the current rates of AC and factors associated with AC among K-12 educators. Methods. A volunteer sample of K-12 educators ( was recruited to participate in an online survey. Participants responded about AC patterns and social ecological influences on AC (individual, interpersonal, institutional, community, and environmental factors. -tests and ANOVAs examined trends in AC, and Pearson correlations examined the relationship between AC and dependent variables. Multiple regression analysis determined the relative influence of individual, interpersonal, institutional, community, and environmental levels on AC. Results. Participants actively commuted times/week. There were several individual, interpersonal, institutional, community, and environmental factors significantly related to AC. The full model explained 60.8% of the variance in AC behavior. Conclusions. This study provides insight on the factors that determine K-12 educators mode of commute and provide some insight for employee wellness among this population.

Student Interest in Engineering Design-Based Science

Science.gov (United States)

Selcen Guzey, S.; Moore, Tamara J.; Morse, Gillian

2016-01-01

Current reform efforts in science education around the world call on teachers to use integrated approaches to teach science. As a part of such reform efforts in the United States, engineering practices and engineering design have been identified in K-12 science education standards. However, there is relatively little is known about effective ways…

Role of alkali carbonate and salt in topochemical synthesis of K1/2Na1/2NbO3 and NaNbO3 templates

Science.gov (United States)

Lee, Jae-Seok; Jeon, Jae-Ho; Choi, Si-Young

2013-11-01

Since the properties of lead-free piezoelectric materials have thus far failed to meet those of lead-based materials, either chemical doping or morphological texturing should be employed to improve the piezoelectric properties of lead-free piezoelectric ceramics. The goal of this study was to synthesize plate-like K1/2Na1/2NbO3 and NaNbO3 particles, which are the most favorable templates for morphological texturing of K1/2Na1/2NbO3 ceramics. To achieve this goal, Bi2.5Na3.5Nb5O18 precursors in a plate-like shape were first synthesized and subsequently converted into K1/2Na1/2NbO3 or NaNbO3 particles that retain the morphology of Bi2.5Na3.5Nb5O18. In this study, we found that sodium or potassium carbonate does not play a major role in converting the Bi2.5Na3.5Nb5O18 precursor to K1/2Na1/2NbO3 or NaNbO3, on the contrary to previous reports; however, the salt contributes to the conversion reaction. All synthesis processes have been performed via a molten salt method, and scanning electron microscopy, scanning probe microscopy, and inductively coupled plasma mass spectroscopy were used to characterize the synthesized K1/2Na1/2NbO3 or NaNbO3 templates.

Hand Movements and Braille Reading Efficiency: Data from the Alphabetic Braille and Contracted Braille Study

Science.gov (United States)

Wright, Tessa; Wormsley, Diane P.; Kamei-Hannan, Cheryl

2009-01-01

Using a subset of data from the Alphabetic Braille and Contracted Braille Study, researchers analyzed the patterns and characteristics of hand movements as predictors of reading performance. Statistically significant differences were found between one- and two-handed readers and between patterns of hand movements and reading rates. (Contains 6…

submitter Development of a 100 kW, 12.5 kV, 22 kHz and 30 kV insulated medium frequency transformer for compact and reliable medium voltage power conversion

CERN Document Server

Isler, Stephane; Aguglia, Davide; Bonnin, Xavier Abel

2017-01-01

This paper presents the critical design aspects addressed during the development of a 100 kW, 12.5 kV, 22 kHz, and 30 kV insulated medium frequency transformer used in a power converter. The transformers are used in a resonant multilevel converter topology producing HV DC voltage from a three phase 400 V AC industrial grid. The power converter is used to supply radio frequency systems in particle accelerators. Considerations about material selection, dielectric, magnetic and thermal design are discussed and experimental results on the full scale transformer and power converter are presented.

The Humanistic Side of Engineering: Considering Social Science and Humanities Dimensions of Engineering in Education and Research

OpenAIRE

Hynes, Morgan; Swenson, Jessica

2013-01-01

Mathematics and science knowledge/skills are most commonly associated with engineering’s pre-requisite knowledge. Our goals in this paper are to argue for a more systematic inclusion of social science and humanities knowledge in the introduction of engineering to K-12 students. As part of this argument, we present a construct for framing the humanistic side of engineering with illustrative examples of what appealing to the humanistic side of engineering can look like in a classroom setting, a...

Integration of Engineering Education by High School Teachers to Meet Standards in the Physics Classroom

Science.gov (United States)

Kersten, Jennifer Anna

In recent years there has been increasing interest in engineering education at the K-12 level, which has resulted in states adopting engineering standards as a part of their academic science standards. From a national perspective, the basis for research into engineering education at the K-12 level is the belief that it is of benefit to student learning, including to "improve student learning and achievement in science and mathematics; increase awareness of engineering and the work of engineers; boost youth interest in pursuing engineering as a career; and increase the technological literacy of all students" (National Research Council, 2009a, p. 1). The above has led to a need to understand how teachers are currently implementing engineering education in their classrooms. High school physics teachers have a history of implementing engineering design projects in their classrooms, thus providing an appropriate setting to look for evidence of quality engineering education at the high school level. Understanding the characteristics of quality engineering integration can inform curricular and professional development efforts for teachers asked to implement engineering in their classrooms. Thus, the question that guided this study is: How, and to what extent, do physics teachers represent quality engineering in a physics unit focused on engineering? A case study research design was implemented for this project. Three high school physics teachers were participants in this study focused on the integration of engineering education into the physics classroom. The data collected included observations, interviews, and classroom documents that were analyzed using the Framework for Quality K-12 Engineering Education (Moore, Glancy et al., 2013). The results provided information about the areas of the K-12 engineering framework addressed during these engineering design projects, and detailed the quality of these lesson components. The results indicate that all of the design

Educating Tomorrow's Workforce: A Report on the Semiconductor Industry's Commitment to Youth in K-12.

Science.gov (United States)

Semiconductor Industry Association, San Jose, CA.

The U.S. semiconductor industry, now the nation's largest manufacturing industry, displays its commitment to training its current workers and educating future workers by supporting educational efforts on the K-12 level. This catalog describes innovative actions by 16 Semiconductor Industry Association companies to improve education at the K-12…

Reading and Engineering: Elementary Students' Co-Application of Comprehension Strategies and Engineering Design Processes

Science.gov (United States)

Wilson-Lopez, Amy; Gregory, Stacie; Larsen, Victor

2016-01-01

For decades, researchers have asserted that K-12 teachers should embed reading comprehension instruction within each academic discipline, including "technical subjects" such as engineering. Recently, this assertion has become a source of controversy among researchers and practitioners who believe that time spent on teaching reading…

Effective Engineering Outreach through an Undergraduate Mentoring Team and Module Database

Science.gov (United States)

Young, Colin; Butterfield, Anthony E.

2014-01-01

The rising need for engineers has led to increased interest in community outreach in engineering departments nationwide. We present a sustainable outreach model involving trained undergraduate mentors to build ties with K-12 teachers and students. An associated online module database of chemical engineering demonstrations, available to educators…

Exploring the Effectiveness of Online Education in K-12 Environments

Science.gov (United States)

Heafner, Tina L., Ed.; Hartshorne, Richard, Ed.; Petty, Teresa, Ed.

2015-01-01

The integration of technology in classrooms is rapidly emerging as a way to provide more educational opportunities for students. As virtual learning environments become more popular, evaluating the impact of this technology on student success is vital. "Exploring the Effectiveness of Online Education in K-12 Environments" combines…

Infrared Astronomy Professional Development for K-12 Educators: WISE Telescope

Science.gov (United States)

Borders, Kareen; Mendez, B. M.

2010-01-01

K-12 educators need effective and relevant astronomy professional development. WISE Telescope (Wide-Field Infrared Survey Explorer) and Spitzer Space Telescope Education programs provided an immersive teacher professional development workshop at Arecibo Observatory in Puerto Rico during the summer of 2009. As many common misconceptions involve scale and distance, teachers worked with Moon/Earth scale, solar system scale, and distance of objects in the universe. Teachers built and used basic telescopes, learned about the history of telescopes, explored ground and satellite based telescopes, and explored and worked on models of WISE Telescope. An in-depth explanation of WISE and Spitzer telescopes gave participants background knowledge for infrared astronomy observations. We taught the electromagnetic spectrum through interactive stations. The stations included an overview via lecture and power point, the use of ultraviolet beads to determine ultraviolet exposure, the study of WISE lenticulars and diagramming of infrared data, listening to light by using speakers hooked up to photoreceptor cells, looking at visible light through diffraction glasses and diagramming the data, protocols for using astronomy based research in the classroom, and infrared thermometers to compare environmental conditions around the observatory. An overview of LIDAR physics was followed up by a simulated LIDAR mapping of the topography of Mars. We will outline specific steps for K-12 infrared astronomy professional development, provide data demonstrating the impact of the above professional development on educator understanding and classroom use, and detail future plans for additional K-12 professional development. Funding was provided by WISE Telescope, Spitzer Space Telescope, Starbucks, Arecibo Observatory, the American Institute of Aeronautics and Astronautics, and the Washington Space Grant Consortium.

Sodium-NaK engineering handbook. Volume III. Sodium systems, safety, handling, and instrumentation. [LMFBR

Energy Technology Data Exchange (ETDEWEB)

Foust, O J [ed.

1978-01-01

The handbook is intended for use by present and future designers in the Liquid Metals Fast Breeder Reactor (LMFBR) Program and by the engineering and scientific community performing other type investigation and exprimentation requiring high-temperature sodium and NaK technology. The arrangement of subject matter progresses from a technological discussion of sodium and sodium--potassium alloy (NaK) to discussions of varius categories and uses of hardware in sodium and NaK systems. Emphasis is placed on sodium and NaK as heat-transport media. Sufficient detail is included for basic understanding of sodium and NaK technology and of technical aspects of sodium and NaK components and instrument systems. Information presented is considered adequate for use in feasibility studies and conceptual design, sizing components and systems, developing preliminary component and system descriptions, identifying technological limitations and problem areas, and defining basic constraints and parameters.

Residual heat use generated by a 12 kW fuel cell in an electric vehicle heating system

International Nuclear Information System (INIS)

Colmenar-Santos, Antonio; Alberdi-Jiménez, Lucía; Nasarre-Cortés, Lorenzo; Mora-Larramona, Joaquín

2014-01-01

A diesel or gasoline vehicle heating is produced by the heat of the engine coolant liquid. Nevertheless, electric vehicles, due to the fact that electric motor transform directly electricity into mechanical energy through electromagnetic interactions, do not generate this heat so other method of providing it has to be developed. This study introduces the system developed in a fuel cell electric vehicle (lithium-ion battery – fuel cell) with residual heat use. The fuel cell electric vehicle is driven by a 12 kW PEM (proton exchange membrane) fuel cell. This fuel cell has an operating temperature around 50 °C. The residual heat generated was originally wasted by interaction with the environment. The new developed heating system designed integrates the heat generated by the fuel cell into the heating system of the vehicle, reducing the global energy consumption and improving the global efficiency as well. - Highlights: • Modification of heating system was done by introducing the residual heat from fuel cell. • Maximum heat achieved by the heating radiator of 9.27 kW. • Reduction of the heat dissipation by the fuel cell cooling system 1.5 kW. • Total efficiency improvement of 20% with an autonomy increase of 21 km

A family of names : rune-names and ogam-names and their relation to alphabet letter-names

NARCIS (Netherlands)

Griffiths, Alan

2013-01-01

The current consensus is that vernacular names assigned to the runes of the Germanic fuþark and to Irish ogam characters are indigenous creations independent of Mediterranean alphabet traditions. I propose, however, that ogam-names are based on interpretations of Hebrew, Greek or Latin letter-names

Transforming K-12 Rural Education through Blended Learning: Teacher Perspectives

Science.gov (United States)

Kellerer, Paula; Kellerer, Eric; Werth, Eric; Werth, Lori; Montgomery, Danielle; Clyde, Rozella; Cozart, Joe; Creach, Laura; Hibbard, Laura; LaFrance, Jason; Rupp, Nadine; Walker, Niki; Carter, Theresa; Kennedy, Kathryn

2014-01-01

A qualitative study exploring rural teacher perspectives on the impact of blended learning on students and teachers was conducted in Idaho during the Fall of 2013. Researchers from Northwest Nazarene University's DOCEO Center in partnership with Idaho Digital Learning Academy (IDLA) and the International Association for K-12 Online Learning…

Problem-Based Learning in the Physical Science Classroom, K-12

Science.gov (United States)

McConnell, Tom J.; Parker, Joyce; Eberhardt, Janet

2018-01-01

"Problem-Based Learning in the Physical Science Classroom, K-12" will help your students truly understand concepts such as motion, energy, and magnetism in true-to-life contexts. The book offers a comprehensive description of why, how, and when to implement problem-based learning (PBL) in your curriculum. Its 14 developmentally…

University of Maine’s Follow a Researcher™ Program: Using Graduate Student Field Research as a Framework to Incorporate Next Generation Science Standards (NGSS) Practices in the K-12 Classroom

OpenAIRE

Kaluzienski, Lynn; Hamley, Catherine; Rodda, Charles; Kranich, Gregory; Wilson, Laura

2016-01-01

Follow a Researcher™ is an innovative University of Maine 4-H program that connects youth with a graduate student who is conducting field research in a remote location. Using technology and social media, K-12 classrooms have an unprecedented opportunity to get to know a student researcher. Youth engage in the research process and witness NGSS Science and Engineering Practices in action.

Observation of. lambda. -hypernuclei in the reaction /sup 12/C(. pi. /sup +/,K/sup +/)/sub. lambda. //sup 12/C

Energy Technology Data Exchange (ETDEWEB)

Milner, E.C.

1985-12-01

The observation of ..lambda..-hypernuclear levels in /sub ..lambda..//sup 12/C by associated production through the (..pi../sup +/,K/sup +/) reaction is reported. Spectrometers used in the measurements are discussed. The /sub ..lambda..//sup 12/C excitation energy spectra were recorded at laboratory scattering angles of 5.6/sup 0/, 10.3/sup 0/, and 15.2/sup 0/. The spectra show two major peaks - one attributed to the ground state, and one about 11 MeV higher in excitation. The peak near 11 MeV excitation energy is believed to be almost entirely composed of a multiplet of three J/sup ..pi../ = 2/sup +/ states. Relativistic DWBA calculations imply support for the expectation that higher spin states are preferentially populated in the (..pi../sup +/,K/sup +/) reaction, compared to the (K/sup -/,..pi../sup -/) reaction in which lower spin states are excited. 29 refs., 40 figs.

An Exploratory Study on K-12 Teachers' Use of Technology and Multimedia in the Classroom

Science.gov (United States)

Martin, Florence; Carr, Marsha L.

2015-01-01

21st century has seen new technology and multimedia made available for integration in K-12 classrooms. This exploratory study examines K-12 teachers' use of technology and multimedia in the classroom in two southern counties in the Southeastern United States. The purpose of the study was to answer the following five research questions: 1) What…

From the Alphabet to the Web

Directory of Open Access Journals (Sweden)

Gevisa La Rocca

2012-04-01

Full Text Available The article discusses the issues of social and cultural construction of the concepts of time, space, and thought. This analysis is matched by a parallel between the physics and those of communication. To be used as a reference is the shift from the Newtonian conception of time and space to the one proposed by Einstein. In fact, the concepts of space and time outlined in Newtonian physics well befits to what is the cultural and experiential that outlines M. McLuhan in his description of the aural and visual culture—an examination that, starting from the introduction of the alphabet, takes us to Gutenberg and the electric media. The revolution introduced by Einstein seems similar to the one that goes to the concepts of time, space, and thought with the advent of the Net. This article includes a review of the literature on the subject, through the lesson of Meyrowitz, McLuhan, Innis, Castells, Appadurai, Manovich, Berners-Lee to get to Carr. Facing this path is referred to as the birth of the hypertext moment of transition from linear thinking to the reticular.

Small-scale CHP Plant based on a 35 kWel Hermetic Four Cylinder Stirling Engine for Biomass Fuels- Development, Technology and Operating Experiences

DEFF Research Database (Denmark)

Obernberger, I.; Carlsen, Henrik; Biedermann, F.

2003-01-01

) process and the Stirling engine process. The ORC process represents an economically interesting technology for small-scale biomass-fired combined heat and power plants in a power range between 400 and 1,500 kWel. A newly developed ORC technology with a nominal electric capacity of 1,000 kW was implemented...... in the biomass CHP plant Lienz (A) in the framework of an EU demonstration project. This plant was put in operation in February 2002. Stirling engines are a promising solution for installations with nominal electric capacities between 10 and 150 kW. A biomass CHP pilot plant based on a 35 kWel-Stirling engine...

Solubilization of Na,K-ATPase from rabbit kidney outer medulla using only C12E8

Directory of Open Access Journals (Sweden)

H.L. Santos

2002-03-01

Full Text Available SDS, C12E8, CHAPS or CHAPSO or a combination of two of these detergents is generally used for the solubilization of Na,K-ATPase and other ATPases. Our method using only C12E8 has the advantage of considerable reduction of the time for enzyme purification, with rapid solubilization and purification in a single chromatographic step. Na,K-ATPase-rich membrane fragments of rabbit kidney outer medulla were obtained without adding SDS. Optimum conditions for solubilization were obtained at 4ºC after rapid mixing of 1 mg of membrane Na,K-ATPase with 1 mg of C12E8/ml, yielding 98% recovery of the activity. The solubilized enzyme was purified by gel filtration on a Sepharose 6B column at 4ºC. Non-denaturing PAGE revealed a single protein band with phosphomonohydrolase activity. The molecular mass of the purified enzyme estimated by gel filtration chromatography was 320 kDa. The optimum apparent pH obtained for the purified enzyme was 7.5 for both PNPP and ATP. The dependence of ATPase activity on ATP concentration showed high (K0.5 = 4.0 µM and low (K0.5 = 1.4 mM affinity sites for ATP, with negative cooperativity. Ouabain (5 mM, oligomycin (1 µg/ml and sodium vanadate (3 µM inhibited the ATPase activity of C12E8-solubilized and purified Na,K-ATPase by 99, 81 and 98.5%, respectively. We have shown that Na,K-ATPase solubilized only with C12E8 can be purified and retains its activity. The activity is consistent with the form of (alphaß2 association.

Examining Student-Adult Relationships during K-12 School Age Years

Science.gov (United States)

Lappi, Shelly J.

2012-01-01

This study examined the relationship between dependent and independent variables and the effects relationships have on K-12 students as they struggle through life stressors. Thus, the research study was based upon this over arching question: How does having positive student-adult relationships impact a student's ability to cope with life…

Geology of the U12n.07 UG-3 drill hole, area 12, Nevada Test Site

International Nuclear Information System (INIS)

Terry, S.S.; Cunningham, M.J.

1975-11-01

The U12n.07 UG-3 horizontal drill hole, located near the eastern edge of the center of Rainier Mesa, Nevada Test Site, was drilled to a total depth of 809 m (2,653 ft). This hole was drilled to further evaluate the tunnel-level stratigraph, and structure southwest of the U12n tunnel complex. The drill hole is collared in the middle of Tertiary tunnel bed 3A and penetrates upsection through tunnel beds 3 and 4 and terminates in subunit 4K, all of Tertiary age. Stratigraphy, structure, engineering geology, and physical properties and their relation to tunnel engineering are discussed

Cloning and expression of the Escherichia coli K-12 sad gene.

OpenAIRE

Marek, L E; Henson, J M

1988-01-01

The Escherichia coli K-12 sad gene, which encodes an NAD-dependent succinic semialdehyde dehydrogenase, was cloned into a high-copy-number vector. Minicells carrying a sad+ plasmid produced a 55,000-dalton peptide, the probable sad gene product.

From algorithmic computing to direct retrieval: evidence from number and alphabetic arithmetic in children and adults.

Science.gov (United States)

Barrouillet, P; Fayol, M

1998-03-01

A number of theories of mental arithmetic suggest that the ability to solve simple addition and subtraction problems develops from an algorithmic strategy toward a strategy based on the direct retrieval of the result from memory. In the experiment presented here, 2nd and 12th graders were asked to solve two tasks of number and alphabet arithmetic. The subjects transformed series of 1 to 4 numbers or letters (item span) by adding or subtracting an operand varying from 1 to 4 (operation span). Although both the item and operation span were associated with major and identical effects in the case of both numbers and letters at 2nd grade, such effects were clearly observable only in the case of letters for the adult subjects. This suggests the use of an algorithmic strategy for both types of material in the case of the children and for the letters only in the case of the adults, who retrieved numerical results directly from memory.

Gender Sorting across K-12 Schools in the United States

Science.gov (United States)

Long, Mark C.; Conger, Dylan

2013-01-01

This article documents evidence of nonrandom gender sorting across K-12 schools in the United States. The sorting exists among coed schools and at all grade levels, and it is highest in the secondary school grades. We observe some gender sorting across school sectors and types: for instance, males are slightly underrepresented in private schools…

Draft Genome Sequence of Escherichia coli K-12 (ATCC 10798)

OpenAIRE

Dimitrova, Daniela; Engelbrecht, Kathleen C.; Putonti, Catherine; Koenig, David W.; Wolfe, Alan J.

2017-01-01

ABSTRACT Here, we present the draft genome sequence of Escherichia coli ATCC 10798. E.?coli ATCC 10798 is a K-12 strain, one of the most well-studied model microorganisms. The size of the genome was 4,685,496?bp, with a G+C content of 50.70%. This assembly consists of 62 contigs and the F plasmid.

Optimizing an Intermittent Stretch Paradigm Using ERK1/2 Phosphorylation Results in Increased Collagen Synthesis in Engineered Ligaments

Science.gov (United States)

Paxton, Jennifer Z.; Hagerty, Paul; Andrick, Jonathan J.

2012-01-01

Dynamic mechanical input is believed to play a critical role in the development of functional musculoskeletal tissues. To study this phenomenon, cyclic uniaxial mechanical stretch was applied to engineered ligaments using a custom-built bioreactor and the effects of different stretch frequency, amplitude, and duration were determined. Stretch acutely increased the phosphorylation of p38 (3.5±0.74-fold), S6K1 (3.9±0.19-fold), and ERK1/2 (2.45±0.32-fold). The phosphorylation of ERK1/2 was dependent on time, rather than on frequency or amplitude, within these constructs. ERK1/2 phosphorylation was similar following stretch at frequencies from 0.1 to 1 Hz and amplitudes from 2.5% to 15%, whereas phosphorylation reached maximal levels at 10 min of stretch and returned toward basal within 60 min of stretch. Following a single 10-min bout of cyclic stretch, the cells remained refractory to a second stretch for up to 6 h. Using the phosphorylation of ERK1/2 as a guide, the optimum stretch paradigm was hypothesized to be 10 min of stretch at 2.5% of resting length repeated every 6 h. Consistent with this hypothesis, 7 days of stretch using this optimized intermittent stretch program increased the collagen content of the grafts more than a continuous stretch program (CTL=3.1%±0.44%; CONT=4.8%±0.30%; and INT=5.9%±0.56%). These results suggest that short infrequent bouts of loading are optimal for improving engineered tendon and ligament physiology. PMID:21902469

Animal products and K-ras codon 12 and 13 mutations in colon carcinomas

NARCIS (Netherlands)

Kampman, E.; Voskuil, D.W.; Kraats, A.A. van; Balder, H.F.; Muijen, G.N.P. van; Goldbohm, R.A.; Veer, P. van 't

2000-01-01

K-ras gene mutations (codons 12 and 13) were determined by PCR-based mutant allele-specific amplification (MASA) in tumour tissue of 185 colon cancer patients: 36% harboured mutations, of which 82% were located in codon 12. High intakes of animal protein, calcium and poultry were differently

K-12 Students' Perceptions of Scientists: Finding a valid measurement and exploring whether exposure to scientists makes an impact

Science.gov (United States)

Hillman, Susan J.; Bloodsworth, Kylie H.; Tilburg, Charles E.; Zeeman, Stephan I.; List, Henrietta E.

2014-10-01

This study was launched from a National Science Foundation GK-12 grant in which graduate fellows in Science, Technology, Engineering, and Mathematics (STEM) are placed in classrooms to engage K-12 students in STEM activities. The investigation explored whether the STEM Fellows' presence impacted the K-12 students' stereotypical image of a scientist. Since finding a valid instrument is critical, the study involved (1) determining the validity of the commonly administered Draw-A-Scientist Test (DAST) against a newly designed six-question survey and (2) using a combination of both instruments to determine what stereotypes are currently held by children. A pretest-posttest design was used on 485 students, grades 3-11, attending 6 different schools in suburban and rural Maine communities. A significant but low positive correlation was found between the DAST and the survey; therefore, it is imperative that the DAST not be used alone, but corroboration with interviews or survey questions should occur. Pretest results revealed that the children held common stereotypes of scientists, but these stereotypes were neither as extensive nor did they increase with the grade level as past research has indicated, suggesting that a shift has occurred with children having a broader concept of who a scientist can be. Finally, the presence of an STEM Fellow corresponded with decreased stereotypes in middle school and high school, but no change in elementary age children. More research is needed to determine whether this reflects resiliency in elementary children's perceptions or limitations in either drawing or in writing out their responses.

Discovery Camp Excites Students about Engineering and Technology Careers

Science.gov (United States)

Massiha, G. H.

2011-01-01

In the United States and elsewhere, there is a dramatic shortage of engineers and technologists. And, unfortunately, these professions often suffer from a lack of awareness among K-12 students. Clearly, educators need to show students the very exciting and lucrative aspects of these fields. Engineering and technology are consistently listed by…

EXCESS MOLAR ENTHALPIES OF 1-OCTENE + DIMETHYLCARBONATE OR DIETHYLCARBONATE OR 1,2-PROPYLCARBONATE AT 363.15 K AND 413.15 K

Directory of Open Access Journals (Sweden)

M. A. KRÄHENBÜHL

1998-03-01

Full Text Available The excess molar enthalpies of 1-octene + dimethylcarbonate or diethylcarbonate or 1,2-propylcarbonate have been measured at two high temperatures 363.15 K and 413.15 K and for pressures varying from 18 to 20 bar with an isothermal flow-calorimeter. All these mixtures have exhibited positive HEm.

Bringing Outreach into the Engineering Classroom--A Mass and Heat Transfer Course Project

Science.gov (United States)

Eniola-Adefeso, Omolola

2010-01-01

One major contributing factor to the low number of students receiving degrees in engineering is the two decades of steady decline in student enrollment in engineering disciplines. Evidence in the literature suggests that this decline can be linked to K-12 students' lack of knowledge of engineering careers and their perception of engineering as…

Escherichia coli K-12 pathogenicity in the pea aphid, Acyrthosiphon pisum, reveals reduced antibacterial defense in aphids.

Science.gov (United States)

Altincicek, Boran; Ter Braak, Bas; Laughton, Alice M; Udekwu, Klas I; Gerardo, Nicole M

2011-10-01

To better understand the molecular basis underlying aphid immune tolerance to beneficial bacteria and immune defense to pathogenic bacteria, we characterized how the pea aphid Acyrthosiphon pisum responds to Escherichia coli K-12 infections. E. coli bacteria, usually cleared in the hemolymph of other insect species, were capable of growing exponentially and killing aphids within a few days. Red fluorescence protein expressing E. coli K-12 laboratory strain multiplied in the aphid hemolymph as well as in the digestive tract, resulting in death of infected aphids. Selected gene deletion mutants of the E. coli K-12 predicted to have reduced virulence during systemic infections showed no difference in either replication or killing rate when compared to the wild type E. coli strain. Of note, however, the XL1-Blue E. coli K-12 strain exhibited a significant lag phase before multiplying and killing aphids. This bacterial strain has recently been shown to be more sensitive to oxidative stress than other E. coli K-12 strains, revealing a potential role for reactive oxygen species-mediated defenses in the otherwise reduced aphid immune system. Copyright © 2011 Elsevier Ltd. All rights reserved.

Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras

Energy Technology Data Exchange (ETDEWEB)

Xu, Shenyuan; Long, Brian N.; Boris, Gabriel H.; Chen, Anqi; Ni, Shuisong; Kennedy, Michael A.

2017-11-10

K-Ras, a molecular switch that regulates cell growth, apoptosis and metabolism, is activated when it undergoes a conformation change upon binding GTP and is deactivated following the hydrolysis of GTP to GDP. Hydrolysis of GTP in water is accelerated by coordination to K-Ras, where GTP adopts a high-energy conformation approaching the transition state. The G12A mutation reduces intrinsic K-Ras GTP hydrolysis by an unexplained mechanism. Here, crystal structures of G12A K-Ras in complex with GDP, GTP, GTPγS and GppNHp, and of Q61A K-Ras in complex with GDP, are reported. In the G12A K-Ras–GTP complex, the switch I region undergoes a significant reorganization such that the Tyr32 side chain points towards the GTP-binding pocket and forms a hydrogen bond to the GTP γ-phosphate, effectively stabilizing GTP in its precatalytic state, increasing the activation energy required to reach the transition state and contributing to the reduced intrinsic GTPase activity of G12A K-Ras mutants.

Technical Feasibility Study for Zero Energy K-12 Schools

Energy Technology Data Exchange (ETDEWEB)

Bonnema, Eric [National Renewable Energy Lab. (NREL), Golden, CO (United States); Goldwasser, David [National Renewable Energy Lab. (NREL), Golden, CO (United States); Torcellini, Paul [National Renewable Energy Lab. (NREL), Golden, CO (United States); Pless, Shanti [National Renewable Energy Lab. (NREL), Golden, CO (United States); Studer, Daniel [National Renewable Energy Lab. (NREL), Golden, CO (United States)

2016-11-01

This technical feasibility study provides documentation and research results supporting a possible set of strategies to achieve source zero energy K-12 school buildings as defined by the U.S. Department of Energy (DOE) zero energy building (ZEB) definition (DOE 2015a). Under this definition, a ZEB is an energy-efficient building in which, on a source energy basis, the actual annual delivered energy is less than or equal to the on-site renewable exported energy.

K-12 Phenology Lessons for the Phenocam Project

Science.gov (United States)

Bennett, K. F.

2013-12-01

Phenology is defined as periodic [or annual] life cycles of plants and animals driven by seasonal environmental changes. Climate change impinges a strong effect on phenology, potentially altering the structure and functioning of ecosystems. In the fall of 2011, the Ashburnham-Westminster Regional School District became the first of five schools to join Harvard University's Phenocam Network with the installation of a webcam to monitor phenology (or 'phenocam') at Overlook Middle School in Ashburnham, Massachusetts. Our school district is now part of a network of near-surface remote sensing phenocams that capture and send images of forest, shrub, and grassland vegetation cover at more than 130 diverse sites in North America. Our phenocam provides a digital image every half hour of the mixed forest canopy north from the school, enabling the detection of changes in canopy development, quantified as canopy 'greenness'. As a part of the Phenocam project, students at the K-12 level have expanded the scope of phenological monitoring protocol that is part of the Harvard Forest Schoolyard Ecology Program, Buds, Leaves, and Global Warming. In this protocol, students work with ecologists at Harvard Forest to monitor buds and leaves on schoolyard trees to determine the length of the growing season, giving them the opportunity to be a part of real and important research concerning the critical environmental issue of climate change. Students involved in the Buds, Leaves, and Global Warming study have the opportunity to compare their ground data on budburst, color change, and leaf drop to the phenocam images, as well as to similar forested sites in locations throughout the United States. Lessons have been developed for comparing student data to phenocam images, canopy greenness time series graphs extracted from the images, and satellite data. Lessons addressing map scale and the Urban Heat Island effect will also be available for teachers. This project will greatly enhance the

Enhancing the Impact of Evidence-Based Publications on K-12 ESL Teacher Practices

Science.gov (United States)

Abbott, Marilyn L.; Lee, Kent; Rossiter, Marian J.

2017-01-01

The reading of current research-informed publications is an essential component of teacher professional development that has the potential to lead to or reinforce the implementation of effective instructional practices. To our knowledge, no studies have examined kindergarten to grade 12 (K-12) ESL teacher engagement in professional reading related…

How Vocational Psychologists Can Make a Difference in K-12 Education

Science.gov (United States)

Perry, Justin C.; Shannon, Lisa

2017-01-01

In general, vocational psychologists have not been engaged in applied research that demonstrates how career interventions can improve educational problems that matter to relevant decision-makers and stakeholders. This article describes how vocational psychology can make a difference in K-12 education by embracing an interdisciplinary…

ONR K-16 Engineering Pipeline: Engineering Success in STEM Project

Science.gov (United States)

2016-10-19

Algebra I Industrial and Engineering - AP Statistics - Algebra II - Precalculus / Technology Core Science: Trigonometry - Calculus - AP...AP Environmental Sequence Science - Algebra II Grade 10 - Precalculus / Engineering Program Trigonometry TIU5810 of Study Cluster -Calculus

Crosstalk between Vitamins A, B12, D, K, C, and E Status and Arterial Stiffness

Science.gov (United States)

Luca, Constantin Tudor

2017-01-01

Arterial stiffness is associated with cardiovascular risk, morbidity, and mortality. The present paper reviews the main vitamins related to arterial stiffness and enabling destiffening, their mechanisms of action, providing a brief description of the latest studies in the area, and their implications for primary cardiovascular prevention, clinical practice, and therapy. Despite inconsistent evidence for destiffening induced by vitamin supplementation in several randomized clinical trials, positive results were obtained in specific populations. The main mechanisms are related to antiatherogenic effects, improvement of endothelial function (vitamins A, C, D, and E) and metabolic profile (vitamins A, B12, C, D, and K), inhibition of the renin-angiotensin-aldosterone system (vitamin D), anti-inflammatory (vitamins A, D, E, and K) and antioxidant effects (vitamins A, C, and E), decrease of homocysteine level (vitamin B12), and reversing calcification of arteries (vitamin K). Vitamins A, B12, C, D, E, and K status is important in evaluating cardiovascular risk, and vitamin supplementation may be an effective, individualized, and inexpensive destiffening therapy. PMID:28167849

Efficient EGR technology for future HD diesel engine emission targets

NARCIS (Netherlands)

Baert, R.S.G.; Beckman, D.E.; Veen, A.

1999-01-01

Different systems for achieving short-route cooled EGR on turbocharged and aftercooled heavy-duty diesel engines have been tested on a 12 litre 315 kW engine with 4 valves per cylinder and an electronically controlled unit pump fuel injection system. In all of these systems the exhaust gas was

Keeping Pace with K-12 Digital Learning: An Annual Review of Policy and Practice. Eleventh Edition

Science.gov (United States)

Watson, John; Pape, Larry; Murin, Amy; Gemin, Butch; Vashaw, Lauren

2014-01-01

"Keeping Pace with K-12 Digital Learning" (2014) is the 11th in a series of annual reports that began in 2004 that examine the status of K-12 online education across the country. The report provides an overview of the latest policies, practices, and trends affecting online learning programs across all 50 states. It summarizes that at a…

Alphabet Writing and Allograph Selection as Predictors of Spelling in Sentences Written by Spanish-Speaking Children Who Are Poor or Good Keyboarders.

Science.gov (United States)

Peake, Christian; Diaz, Alicia; Artiles, Ceferino

This study examined the relationship and degree of predictability that the fluency of writing the alphabet from memory and the selection of allographs have on measures of fluency and accuracy of spelling in a free-writing sentence task when keyboarding. The Test Estandarizado para la Evaluación de la Escritura con Teclado ("Spanish Keyboarding Writing Test"; Jiménez, 2012) was used as the assessment tool. A sample of 986 children from Grades 1 through 3 were classified according to transcription skills measured by keyboard ability (poor vs. good) across the grades. Results demonstrated that fluency in writing the alphabet and selecting allographs mediated the differences in spelling between good and poor keyboarders in the free-writing task. Execution in the allograph selection task and writing alphabet from memory had different degrees of predictability in each of the groups in explaining the level of fluency and spelling in the free-writing task sentences, depending on the grade. These results suggest that early assessment of writing by means of the computer keyboard can provide clues and guidelines for intervention and training to strengthen specific skills to improve writing performance in the early primary grades in transcription skills by keyboarding.

GenoBase: comprehensive resource database of Escherichia coli K-12.

Science.gov (United States)

Otsuka, Yuta; Muto, Ai; Takeuchi, Rikiya; Okada, Chihiro; Ishikawa, Motokazu; Nakamura, Koichiro; Yamamoto, Natsuko; Dose, Hitomi; Nakahigashi, Kenji; Tanishima, Shigeki; Suharnan, Sivasundaram; Nomura, Wataru; Nakayashiki, Toru; Aref, Walid G; Bochner, Barry R; Conway, Tyrrell; Gribskov, Michael; Kihara, Daisuke; Rudd, Kenneth E; Tohsato, Yukako; Wanner, Barry L; Mori, Hirotada

2015-01-01

Comprehensive experimental resources, such as ORFeome clone libraries and deletion mutant collections, are fundamental tools for elucidation of gene function. Data sets by omics analysis using these resources provide key information for functional analysis, modeling and simulation both in individual and systematic approaches. With the long-term goal of complete understanding of a cell, we have over the past decade created a variety of clone and mutant sets for functional genomics studies of Escherichia coli K-12. We have made these experimental resources freely available to the academic community worldwide. Accordingly, these resources have now been used in numerous investigations of a multitude of cell processes. Quality control is extremely important for evaluating results generated by these resources. Because the annotation has been changed since 2005, which we originally used for the construction, we have updated these genomic resources accordingly. Here, we describe GenoBase (http://ecoli.naist.jp/GB/), which contains key information about comprehensive experimental resources of E. coli K-12, their quality control and several omics data sets generated using these resources. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

Makerspaces: The Next Iteration for Educational Technology in K-12 Schools

Science.gov (United States)

Strycker, Jesse

2015-01-01

With the continually growing number of computers and mobile devices available in K-12 schools, the need is dwindling for dedicated computer labs and media centers. Some schools are starting to repurpose those facilities into different kinds of exploratory learning environments known as "makerspaces". This article discusses this next…

Are K-12 Learners Motivated in Physical Education? A Meta-Analysis

Science.gov (United States)

Chen, Senlin; Chen, Ang; Zhu, Xihe

2012-01-01

Previous studies devoted to K-12 learner motivation in physical education share a general assumption that students may lack motivation. This meta-analytic study examined published original studies (n = 79) to determine students' motivation level and the association between motivation and outcomes. Original means of motivation measures were…

High School Student Perceptions of the Utility of the Engineering Design Process: Creating Opportunities to Engage in Engineering Practices and Apply Math and Science Content

Science.gov (United States)

Berland, Leema; Steingut, Rebecca; Ko, Pat

2014-01-01

Research and policy documents increasingly advocate for incorporating engineering design into K-12 classrooms in order to accomplish two goals: (1) provide an opportunity to engage with science content in a motivating real-world context; and (2) introduce students to the field of engineering. The present study uses multiple qualitative data…

Anti-ageing effects of a new synthetic sphingolipid (K6EAA-L12) on aged murine skin.

Science.gov (United States)

Jung, Minyoung; Lee, Sanghoon; Park, Hwa-young; Youm, Jong-Kyung; Jeong, Sekyoo; Bae, Jonghwan; Kwon, Mi Jung; Park, Byeong Deog; Lee, Seung Hun; Choi, Eung Ho

2011-04-01

Recently, we reported on the anti-ageing effects of K6PC-5. This compound induced keratinocyte differentiation and fibroblast proliferation by increasing sphingosine-1 phosphate synthesis. We performed this study to confirm the anti-ageing effects of new synthetic products (the K6EAA series) derived from K6PC-5 through an amino group induction. Cellular responses such as differentiation, proliferation and calcium mobilization were investigated using cultured human keratinocytes and fibroblasts. Also, we measured the expressions of collagen mRNA and protein using real time RT-PCR and ELISA, respectively. The K6EAA-L12 product, selected by in vitro screening, was evaluated for anti-ageing effects on intrinsically and extrinsically (photo) aged models of hairless mice. In the intrinsically aged murine skin, K6EAA-L12 showed anti-ageing effects by activating collagen synthesis, eventually causing dermal thickening. Also, in the photo-aged skin, the dermal collagen density and dermal thickness were increased. In photo-aged murine skin, K6EAA-L12 increased stratum corneum integrity by increasing corneodesmosome density and improved the barrier recovery rate. However, there were no changes in the expressions of epidermal differentiation maker proteins. In conclusion, topical K6EAA-L12, a new synthetic K6PC-5 derivative, improves intrinsically and extrinsically (photo) aged skin by increasing the collagen density and improving the skin barrier function. © 2011 John Wiley & Sons A/S.

Technical Support Document: Development of the Advanced Energy Design Guide for K-12 Schools--30% Energy Savings

Energy Technology Data Exchange (ETDEWEB)

Pless, S.; Torcellini, P.; Long, N.

2007-09-01

This Technical Support Document describes the process and methodology for the development of the Advanced Energy Design Guide for K-12 School Buildings (K-12 AEDG), a design guidance document intended to provide recommendations for achieving 30% energy savings in K-12 Schools over levels contained in ANSI/ASHRAE/IESNA Standard 90.1-1999, Energy Standard for Buildings Except Low-Rise Residential Buildings. The 30% energy savings target is the first step toward achieving net-zero energy schools; schools that, on an annual basis, draw from outside sources less or equal energy than they generate on site from renewable energy sources.

I12: the Joint Engineering, Environment and Processing (JEEP) beamline at Diamond Light Source.

Science.gov (United States)

Drakopoulos, Michael; Connolley, Thomas; Reinhard, Christina; Atwood, Robert; Magdysyuk, Oxana; Vo, Nghia; Hart, Michael; Connor, Leigh; Humphreys, Bob; Howell, George; Davies, Steve; Hill, Tim; Wilkin, Guy; Pedersen, Ulrik; Foster, Andrew; De Maio, Nicoletta; Basham, Mark; Yuan, Fajin; Wanelik, Kaz

2015-05-01

I12 is the Joint Engineering, Environmental and Processing (JEEP) beamline, constructed during Phase II of the Diamond Light Source. I12 is located on a short (5 m) straight section of the Diamond storage ring and uses a 4.2 T superconducting wiggler to provide polychromatic and monochromatic X-rays in the energy range 50-150 keV. The beam energy enables good penetration through large or dense samples, combined with a large beam size (1 mrad horizontally × 0.3 mrad vertically). The beam characteristics permit the study of materials and processes inside environmental chambers without unacceptable attenuation of the beam and without the need to use sample sizes which are atypically small for the process under study. X-ray techniques available to users are radiography, tomography, energy-dispersive diffraction, monochromatic and white-beam two-dimensional diffraction/scattering and small-angle X-ray scattering. Since commencing operations in November 2009, I12 has established a broad user community in materials science and processing, chemical processing, biomedical engineering, civil engineering, environmental science, palaeontology and physics.

Genotyping of K-ras codons 12 and 13 mutations in colorectal cancer by capillary electrophoresis.

Science.gov (United States)

Chen, Yen-Ling; Chang, Ya-Sian; Chang, Jan-Gowth; Wu, Shou-Mei

2009-06-26

Point mutations of the K-ras gene located in codons 12 and 13 cause poor responses to the anti-epidermal growth factor receptor (anti-EGFR) therapy of colorectal cancer (CRC) patients. Besides, mutations of K-ras gene have also been proven to play an important role in human tumor progression. We established a simple and effective capillary electrophoresis (CE) method for simultaneous point mutation detection in codons 12 and 13 of K-ras gene. We combined one universal fluorescence-based nonhuman-sequence primer and two fragment-oriented primers in one tube, and performed this two-in-one polymerase chain reaction (PCR). PCR fragments included wild type and seven point mutations at codons 12 and 13 of K-ras gene. The amplicons were analyzed by single-strand conformation polymorphism (SSCP)-CE method. The CE analysis was performed by using a 1x Tris-borate-EDTA (TBE) buffer containing 1.5% (w/v) hydroxyethylcellulose (HEC) (MW 250,000) under reverse polarity with 15 degrees C and 30 degrees C. Ninety colorectal cancer patients were blindly genotyped using this developed method. The results showed good agreement with those of DNA sequencing method. The SSCP-CE was feasible for mutation screening of K-ras gene in populations.

Draft Genome Sequence of Escherichia coli K-12 (ATCC 10798).

Science.gov (United States)

Dimitrova, Daniela; Engelbrecht, Kathleen C; Putonti, Catherine; Koenig, David W; Wolfe, Alan J

2017-07-06

Here, we present the draft genome sequence of Escherichia coli ATCC 10798. E. coli ATCC 10798 is a K-12 strain, one of the most well-studied model microorganisms. The size of the genome was 4,685,496 bp, with a G+C content of 50.70%. This assembly consists of 62 contigs and the F plasmid. Copyright © 2017 Dimitrova et al.

Spark ignition engine performance and emissions in a high compression engine using biogas and methane mixtures without knock occurrence

Directory of Open Access Journals (Sweden)

Gómez Montoya Juan Pablo

2015-01-01

Full Text Available With the purpose to use biogas in an internal combustion engine with high compression ratio and in order to get a high output thermal efficiency, this investigation used a diesel engine with a maximum output power 8.5 kW, which was converted to spark ignition mode to use it with gaseous fuels. Three fuels were used: Simulated biogas, biogas enriched with 25% and 50% methane by volume. After conversion, the output power of the engine decreased by 17.64% when using only biogas, where 7 kW was the new maximum output power of the engine. The compression ratio was kept at 15.5:1, and knocking did not occur during engine operation. Output thermal efficiency operating the engine in SI mode with biogas enriched with 50% methane was almost the same compared with the engine running in diesel-biogas dual mode at full load and was greater at part loads. The dependence of the diesel pilot was eliminated when biogas was used in the engine converted in SI mode. The optimum condition of experiment for the engine without knocking was using biogas enriched with 50% methane, with 12 degrees of spark timing advance and equivalence ratio of 0.95, larger output powers and higher values of methane concentration lead the engine to knock operation. The presence of CO2 allows operating engines at high compression ratios with normal combustion conditions. Emissions of nitrogen oxides, carbon monoxide and unburnt methane all in g/kWh decreased when the biogas was enriched with 50% methane.

Curriculum Guide for Music Education, K-12. Bulletin 1978, No. 18.

Science.gov (United States)

Alabama State Dept. of Education, Montgomery.

This curriculum guide contains objectives, activities, and evaluation procedures for a K-12 music education program. It would be useful to anyone responsible for teaching music. The authors believe that music education has the dual obligation of developing the aesthetic sensitivity of all students regardless of their individual levels of musical…

Increasing Diversity in K-12 School Leadership. Policy Brief 2018-3

Science.gov (United States)

Castro, Andrene; Germain, Emily; Gooden, Mark

2018-01-01

Principals represent the most "visible" form of leadership in schools, but current workforce data show that K-12 school principals are overwhelmingly white and fail to reflect the diversity within the student population. With increased policy focus on teacher diversity, equal attention must also be directed towards the lack of diversity…

Involvement of IGF-1 and MEOX2 in PI3K/Akt1/2 and ERK1/2 pathways mediated proliferation and differentiation of perivascular adipocytes

International Nuclear Information System (INIS)

Liu, Ping; Kong, Feng; Wang, Jue; Lu, Qinghua; Xu, Haijia; Qi, Tonggang; Meng, Juan

2015-01-01

Perivascular adipocyte (PVAC) proliferation and differentiation were closely involved in cardiovascular disease. We aimed to investigate whether phosphatidylinositol 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) signaling pathways enhance PVAC functions activated by insulin-like growth factor 1(IGF-1) and suppressed by mesenchyme homeobox 2 (MEOX2). In this study, PVACs from primary culture were cultured and induced to differentiate. Cell viability assays demonstrated that IGF-1 promoted PVAC proliferation and differentiation. However MEOX2 counteracted these IGF-1-mediated actions. Flow Cytometry revealed that IGF-1 increased S phase cells and decreased apoptosis; however, MEOX2 decreased S phase cells, increased G0–G1 phase cells, and promoted apoptosis. During PVAC proliferation and differentiation, IGF-1 activated PI3K/Akt1/2 and ERK1/2 signaling pathways, upregulated the expression of these signaling proteins and FAS, and increased PVAC lipid content. In contrast, MEOX2 constrained the phosphorylation of ERK1/2 and Akt1/2 protein, down-regulated these signaling molecules and FAS, and decreased PVAC lipid content. Instead, MEOX2 knockdown enhanced the ERK1/2 and Akt1/2 phosphorylation, augmented the expression of these signaling molecules and FAS, and increased PVAC lipid content. Our findings suggested that PI3K/Akt1/2 and ERK1/2 activation mediated by IGF-1 is essential for PVAC proliferation and differentiation, and MEOX2 is a promising therapeutic gene to intervene in the signaling pathways and inhibit PVAC functions. - Highlights: • IGF-1 activated PI3K/Akt2 and ERK1/2 pathways to mediate PVAC proliferation and differentiation. • The expression of ERK1, ERK 2, PI3K, Akt1 and Akt2 showed different change trends between PVAC proliferation and differentiation. • MEOX2 effectively expressed in PVAC, increased early and late cellular apoptosis, and inhibited its proliferation. • MEOX2 depressed PVAC differentiation and FAS expression

Involvement of IGF-1 and MEOX2 in PI3K/Akt1/2 and ERK1/2 pathways mediated proliferation and differentiation of perivascular adipocytes

Energy Technology Data Exchange (ETDEWEB)

Liu, Ping, E-mail: lping@sdu.edu.cn [Department of Cardiology, The Second Hospital of Shandong University, No. 247, Beiyuan Road, Shandong, Jinan 250033 (China); Kong, Feng; Wang, Jue [Central Laboratory, The Second Hospital of Shandong University, Shandong, Jinan 250033 (China); Lu, Qinghua [Department of Cardiology, The Second Hospital of Shandong University, No. 247, Beiyuan Road, Shandong, Jinan 250033 (China); Xu, Haijia [Department of Cardiology, Wendeng Central Hospital of Weihai City, Shandong, Weihai 264400 (China); Qi, Tonggang [Central Laboratory, The Second Hospital of Shandong University, Shandong, Jinan 250033 (China); Meng, Juan [Department of Cardiology, The Second Hospital of Shandong University, No. 247, Beiyuan Road, Shandong, Jinan 250033 (China)

2015-02-01

Perivascular adipocyte (PVAC) proliferation and differentiation were closely involved in cardiovascular disease. We aimed to investigate whether phosphatidylinositol 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) signaling pathways enhance PVAC functions activated by insulin-like growth factor 1(IGF-1) and suppressed by mesenchyme homeobox 2 (MEOX2). In this study, PVACs from primary culture were cultured and induced to differentiate. Cell viability assays demonstrated that IGF-1 promoted PVAC proliferation and differentiation. However MEOX2 counteracted these IGF-1-mediated actions. Flow Cytometry revealed that IGF-1 increased S phase cells and decreased apoptosis; however, MEOX2 decreased S phase cells, increased G0–G1 phase cells, and promoted apoptosis. During PVAC proliferation and differentiation, IGF-1 activated PI3K/Akt1/2 and ERK1/2 signaling pathways, upregulated the expression of these signaling proteins and FAS, and increased PVAC lipid content. In contrast, MEOX2 constrained the phosphorylation of ERK1/2 and Akt1/2 protein, down-regulated these signaling molecules and FAS, and decreased PVAC lipid content. Instead, MEOX2 knockdown enhanced the ERK1/2 and Akt1/2 phosphorylation, augmented the expression of these signaling molecules and FAS, and increased PVAC lipid content. Our findings suggested that PI3K/Akt1/2 and ERK1/2 activation mediated by IGF-1 is essential for PVAC proliferation and differentiation, and MEOX2 is a promising therapeutic gene to intervene in the signaling pathways and inhibit PVAC functions. - Highlights: • IGF-1 activated PI3K/Akt2 and ERK1/2 pathways to mediate PVAC proliferation and differentiation. • The expression of ERK1, ERK 2, PI3K, Akt1 and Akt2 showed different change trends between PVAC proliferation and differentiation. • MEOX2 effectively expressed in PVAC, increased early and late cellular apoptosis, and inhibited its proliferation. • MEOX2 depressed PVAC differentiation and FAS expression

Non-stoichiometry in the KMo2P3O12-tunnel structure: The oxide K0.75MoNbP3O12

International Nuclear Information System (INIS)

Leclaire, A.; Borel, M.M.; Grandin, A.; Raveau, B.

1990-01-01

K 0.75 MoNbP 3 O 12 , M r =503.009, orthorhombic, Pbcm, a=8.8518 (5), b=9.1453 (11), c=12.5174 (11) A, V=1013.3 (3) A 3 , Z=4, D x =3.300 Mg m -3 , λ(Mo Kα)=0.71073 A, μ=3.13 mm -1 , F(000)=953, T=294 K, R=0.029, wR=0.033 for 1235 observed reflections. This compound is isostructural with KMo 2 P 3 O 12 -type oxides. Its framework is built up from MoO 6 octahedra and PO 4 tetrahedra which delimit tunnels running along b. Different from KMo 2 P 3 O 12 , the tunnels are partly occupied by the potassium ions which are distributed at random. (orig.)

Using Scientific Visualizations to Enhance Scientific Thinking In K-12 Geoscience Education

Science.gov (United States)

Robeck, E.

2016-12-01

The same scientific visualizations, animations, and images that are powerful tools for geoscientists can serve an important role in K-12 geoscience education by encouraging students to communicate in ways that help them develop habits of thought that are similar to those used by scientists. Resources such as those created by NASA's Scientific Visualization Studio (SVS), which are intended to inform researchers and the public about NASA missions, can be used in classrooms to promote thoughtful, engaged learning. Instructional materials that make use of those visualizations have been developed and are being used in K-12 classrooms in ways that demonstrate the vitality of the geosciences. For example, the Center for Geoscience and Society at the American Geosciences Institute (AGI) helped to develop a publication that outlines an inquiry-based approach to introducing students to the interpretation of scientific visualizations, even when they have had little to no prior experience with such media. To facilitate these uses, the SVS team worked with Center staff and others to adapt the visualizations, primarily by removing most of the labels and annotations. Engaging with these visually compelling resources serves as an invitation for students to ask questions, interpret data, draw conclusions, and make use of other processes that are key components of scientific thought. This presentation will share specific resources for K-12 teaching (all of which are available online, from NASA, and/or from AGI), as well as the instructional principles that they incorporate.

Plickers: A Formative Assessment Tool for K-12 and PETE Professionals

Science.gov (United States)

Krause, Jennifer M.; O'Neil, Kason; Dauenhauer, Brian

2017-01-01

Classroom response systems have become popular in K-12 and higher education settings in recent years in order to gauge student learning. The physical education environment is unique in that it is difficult to manage the technology associated with these systems, and therefore, student assessment can be cumbersome. A free classroom response system…

Battling Obesity in K-12 Learners from an Exercise Physiology Perspective

Science.gov (United States)

Rattigan, Peter; Biren, Greg

2007-01-01

Physical education practitioners and programs have the opportunity and obligation to help children become physically educated, healthy, and active adults. This article discusses the battle against obesity in K-12 learners from an exercise physiology perspective and focuses on the fact that practitioners have all the tools they need to battle this…

Fabrication and Piezoelectric Properties of Textured (Bi1/2K1/2)TiO3 Ferroelectric Ceramics

Science.gov (United States)

Nagata, Hajime; Saitoh, Masahiro; Hiruma, Yuji; Takenaka, Tadashi

2010-09-01

Textured (Bi1/2K1/2)TiO3 (BKT) ceramics were prepared by a reactive templated grain growth (RTGG) method to improve their piezoelectric properties. Also, a hot-pressing (HP) method was modified on the basis of RTGG method to obtain dense ceramics and promote the grain orientation. The textured BKT ceramics prepared by the RTGG and HP methods exhibited a relatively high orientation factor F of 0.82 and a high density ratio of 95-99%. Scanning electron microscopy (SEM) micrographs of the textured HP-BKT indicated a textured and poreless microstructure. In addition, the resistivity of the textured HP-BKT was 1.73×1013 Ω·cm. The piezoelectric strain constant d33 determined by means of resonance and antiresonance method was 125 pC/N for the direction parallel to the sheet-stacking direction of the RTGG process. From the measurement of field-induced stain, the normalized d33* (=Smax/Emax) at 80 kV/cm were 127 and 238 pm/V on the randomly oriented and textured samples (F=0.82) for the (∥) direction, respectively.

K-12 Schools: The Effect of Public School Choices on Marine Families’ Co-Location Decisions

Science.gov (United States)

2017-03-01

3. REPORT TYPE AND DATES COVERED Master’s thesis 4. TITLE AND SUBTITLE K-12 SCHOOLS: THE EFFECT OF PUBLIC SCHOOL CHOICES ON MARINE FAMILIES’ CO...be educated ? One theory regarding decision-making in general is the rational choice theory . This approach to explaining the process of making...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS Approved for public release. Distribution is unlimited. K-12 SCHOOLS

Synthesis, crystal structure and characterizations of a new red phosphor K{sub 3}EuB{sub 6}O{sub 12}

Energy Technology Data Exchange (ETDEWEB)

Zhao, Dan, E-mail: iamzd1996@163.com [College of Chemistry and Chemical Engineering, Henan Polytechnic University, Jiaozuo, Henan, 454000 (China); State Key Laboratory of Structural Chemistry, Fuzhou, Fujian, 350002 (China); Ma, Fa-Xue; Wu, Zhi-Qiang; Zhang, Lei [College of Chemistry and Chemical Engineering, Henan Polytechnic University, Jiaozuo, Henan, 454000 (China); Wei, Wei, E-mail: wwei@cnu.edu.cn [Department of Chemistry, Capital Normal University, Beijing, 100048 (China); Yang, Juan; Zhang, Rong-Hua; Chen, Peng-Fei; Wu, Shan-Xuan [College of Chemistry and Chemical Engineering, Henan Polytechnic University, Jiaozuo, Henan, 454000 (China)

2016-10-01

A new potassium europium borate K{sub 3}EuB{sub 6}O{sub 12} has been prepared using a high temperature molten salt method and structurally characterized by single crystal X-ray diffraction (SC-XRD) analyses. Its structure features a three-dimensional (3D) framework composed of isolated [B{sub 5}O{sub 10}]{sup 5−} anions that are bridged by K{sup +} and Eu{sup 3+} ions. In this structure, one crystallographic distinct atom site is mixed occupied by K/Eu at a molar ratio of 1:1. The self-activated photoluminescence (PL) of K{sub 3}EuB{sub 6}O{sub 12} was studied. The excitation spectrum covers a wide range from 322 to 466 nm, which suggests that the K{sub 3}EuB{sub 6}O{sub 12} phosphors can be effectively excited by a near-UV light source. The emission spectrum consists of groups of lines in the red spectral region due to the {sup 5}D{sub 0}→{sup 7}F{sub j} (j = 1, 2, 3, 4) electronic transitions of Eu{sup 3+} ions, with the most intense line at 611 nm. We may expect that K{sub 3}EuB{sub 6}O{sub 12} has the potential to be a red phosphor pumped by near-UV LED chips. - Highlights: • A new red phosphor K{sub 3}EuB{sub 6}O{sub 12} was prepared. • The crystal structure of K{sub 3}EuB{sub 6}O{sub 12} was determined for the first time. • The photoluminescence properties of K{sub 3}EuB{sub 6}O{sub 12} are studied. • K{sub 3}EuB{sub 6}O{sub 12} show intense self-activated red emission under near-UV light excitation.

SA-Search: a web tool for protein structure mining based on a Structural Alphabet

OpenAIRE

Guyon, Frédéric; Camproux, Anne-Claude; Hochez, Joëlle; Tufféry, Pierre

2004-01-01

SA-Search is a web tool that can be used to mine for protein structures and extract structural similarities. It is based on a hidden Markov model derived Structural Alphabet (SA) that allows the compression of three-dimensional (3D) protein conformations into a one-dimensional (1D) representation using a limited number of prototype conformations. Using such a representation, classical methods developed for amino acid sequences can be employed. Currently, SA-Search permits the performance of f...

K-Basins design guidelines

International Nuclear Information System (INIS)

Roe, N.R.; Mills, W.C.

1995-06-01

The purpose of the design guidelines is to enable SNF and K Basin personnel to complete fuel and sludge removal, and basin water mitigation by providing engineering guidance for equipment design for the fuel basin, facility modifications (upgrades), remote tools, and new processes. It is not intended to be a purchase order reference for vendors. The document identifies materials, methods, and components that work at K Basins; it also Provides design input and a technical review process to facilitate project interfaces with operations in K Basins. This document is intended to compliment other engineering documentation used at K Basins and throughout the Spent Nuclear Fuel Project. Significant provisions, which are incorporated, include portions of the following: General Design Criteria (DOE 1989), Standard Engineering Practices (WHC-CM-6-1), Engineering Practices Guidelines (WHC 1994b), Hanford Plant Standards (DOE-RL 1989), Safety Analysis Manual (WHC-CM-4-46), and Radiological Design Guide (WHC 1994f). Documents (requirements) essential to the engineering design projects at K Basins are referenced in the guidelines

Mining protein loops using a structural alphabet and statistical exceptionality

Directory of Open Access Journals (Sweden)

Martin Juliette

2010-02-01

Full Text Available Abstract Background Protein loops encompass 50% of protein residues in available three-dimensional structures. These regions are often involved in protein functions, e.g. binding site, catalytic pocket... However, the description of protein loops with conventional tools is an uneasy task. Regular secondary structures, helices and strands, have been widely studied whereas loops, because they are highly variable in terms of sequence and structure, are difficult to analyze. Due to data sparsity, long loops have rarely been systematically studied. Results We developed a simple and accurate method that allows the description and analysis of the structures of short and long loops using structural motifs without restriction on loop length. This method is based on the structural alphabet HMM-SA. HMM-SA allows the simplification of a three-dimensional protein structure into a one-dimensional string of states, where each state is a four-residue prototype fragment, called structural letter. The difficult task of the structural grouping of huge data sets is thus easily accomplished by handling structural letter strings as in conventional protein sequence analysis. We systematically extracted all seven-residue fragments in a bank of 93000 protein loops and grouped them according to the structural-letter sequence, named structural word. This approach permits a systematic analysis of loops of all sizes since we consider the structural motifs of seven residues rather than complete loops. We focused the analysis on highly recurrent words of loops (observed more than 30 times. Our study reveals that 73% of loop-lengths are covered by only 3310 highly recurrent structural words out of 28274 observed words. These structural words have low structural variability (mean RMSd of 0.85 Å. As expected, half of these motifs display a flanking-region preference but interestingly, two thirds are shared by short (less than 12 residues and long loops. Moreover, half of

Mining protein loops using a structural alphabet and statistical exceptionality.

Science.gov (United States)

Regad, Leslie; Martin, Juliette; Nuel, Gregory; Camproux, Anne-Claude

2010-02-04

Protein loops encompass 50% of protein residues in available three-dimensional structures. These regions are often involved in protein functions, e.g. binding site, catalytic pocket... However, the description of protein loops with conventional tools is an uneasy task. Regular secondary structures, helices and strands, have been widely studied whereas loops, because they are highly variable in terms of sequence and structure, are difficult to analyze. Due to data sparsity, long loops have rarely been systematically studied. We developed a simple and accurate method that allows the description and analysis of the structures of short and long loops using structural motifs without restriction on loop length. This method is based on the structural alphabet HMM-SA. HMM-SA allows the simplification of a three-dimensional protein structure into a one-dimensional string of states, where each state is a four-residue prototype fragment, called structural letter. The difficult task of the structural grouping of huge data sets is thus easily accomplished by handling structural letter strings as in conventional protein sequence analysis. We systematically extracted all seven-residue fragments in a bank of 93000 protein loops and grouped them according to the structural-letter sequence, named structural word. This approach permits a systematic analysis of loops of all sizes since we consider the structural motifs of seven residues rather than complete loops. We focused the analysis on highly recurrent words of loops (observed more than 30 times). Our study reveals that 73% of loop-lengths are covered by only 3310 highly recurrent structural words out of 28274 observed words). These structural words have low structural variability (mean RMSd of 0.85 A). As expected, half of these motifs display a flanking-region preference but interestingly, two thirds are shared by short (less than 12 residues) and long loops. Moreover, half of recurrent motifs exhibit a significant level of

Rube Goldbergineering: Lessons In Teaching Engineering Design To Future Engineers

OpenAIRE

Jordan, Shawn; Pereira, Nielsen

2009-01-01

Hands-on learning experiences and interactive learning environments can be effective in teaching K-12 students. Design, in essence, is an interactive, hands-on experience. Engineering design can be taught in the classroom using innovative hands-on projects, such as designing and building serve to teach design, promote creativity, and provide opportunities for hands-on problem solving, in addition to giving students experience working in cooperative teams. In turn, these experiences could enco...

4-thiouridine and photoprotection in Escherichia coli K12

International Nuclear Information System (INIS)

Thomas, Gilles; Favre, Alain

1977-01-01

A high level of protection is observed in the Escherichia coli K 12 strain AB 1157 rec A 1 nuv + whose transfer RNA contains 4-thiouridine. In contrast, the photoprotection level is low and observed at higher doses in a strain which differs from the former by a single mutation nuv - , (lack of 4-thiouridine). This nucleoside is therefore an important chromophore leading to photoprotection. This conclusion is corroborated by the similarity of the action spectra for 8-13 link formation in tRNA and for photoprotection [fr

Outstanding Science Trade Books for Students K-12: Books Published in 2015

Science.gov (United States)

Science and Children, 2016

2016-01-01

Science teachers and mentors continue to be challenged to meet the high expectations of "A Framework for K-12 Science Education" and the "Next Generation Science Standards" ("NGSS"). Indeed the "Framework" urges to help learners "[build] progressively more sophisticated explanations of natural…

CIT2016: 12. Congress of Transport Engineering, 7-9 June 2016, Valencia (Spain)

Energy Technology Data Exchange (ETDEWEB)

NONE

2016-07-01

The 12 Conference on Transport Engineering (CIT 2016) will be held in Valencia (Spain), from 7-9 June 2016. The CIT2016 will take place in the School of Civil Engineers, Universitat Politècnica de València. As in previous editions, CIT 2016 aims to foster the national and international exchange of scientific and professional works in different transport areas. The theme of the CIT 2016 is: “Efficient, Safe and Intelligent Transport”.

GIS in the K-12 Classroom: Research Agenda from EDGIS '96

OpenAIRE

National Center for Geographic Information and Analysis; National Council for Geographic Education (NCGE); Technical Education Research Centers (TERC)

1996-01-01

This meeting of education researchers and teachers immediately followed the November 1996 Annual Meeting of the National Council for Geographic Education (NCGE) in Santa Barbara, California. Participants explored the issues facing the use of Geographic Information Systems (GIS) in the K-12 classroom and developed a research agenda related to Pedagogy Issues, Curriculum Issues, Software Issues, and Cognitive Issues.

How Do K-12 Students' Manage Applications on Their Mobile Devices?

Science.gov (United States)

Aladjem, Ruthi; Hardof, Sharon

2016-01-01

Personal information management (PIM) is a research field that examines the activities by which users save, organize and retrieve personal information items. PIM is a one of the essential new literacies for learners in the 21st century. This paper reports results from a pilot study that explored PIM practices and strategies of K-12 students, on…

One-to-One Technology in K-12 Classrooms: A Review of the Literature from 2004 through 2014

Science.gov (United States)

Harper, Ben; Milman, Natalie B.

2016-01-01

This literature review examined empirical research conducted between 2004 and 2014 regarding 1:1 technologies in K-12 educational settings. Our overarching research question was: What does research tell us about 1:1 technology in K-12 classrooms? We used the constant-comparative method to analyze, code, and induce themes from 46 relevant articles.…

Integral Representation of the Pictorial Proof of Sum of [superscript n][subscript k=1]k[superscript 2] = 1/6n(n+1)(2n+1)

Science.gov (United States)

Kobayashi, Yukio

2011-01-01

The pictorial proof of the sum of [superscript n][subscript k=1] k[superscript 2] = 1/6n(n+1)(2n+1) is represented in the form of an integral. The integral representations are also applicable to the sum of [superscript n][subscript k-1] k[superscript m] (m greater than or equal to 3). These representations reveal that the sum of [superscript…

Electric propulsion options for 10 kW class earth space missions

Science.gov (United States)

Patterson, M. J.; Curran, Francis M.

1989-01-01

Five and 10 kW ion and arcjet propulsion system options for a near-term space demonstration experiment have been evaluated. Analyses were conducted to determine first-order propulsion system performance and system component mass estimates. Overall mission performance of the electric propulsion systems was quantified in terms of the maximum thrusting time, total impulse, and velocity increment capability available when integrated onto a generic spacecraft under fixed mission model assumptions. Maximum available thrusting times for the ion-propelled spacecraft options, launched on a DELTA II 6920 vehicle, range from approximately 8,600 hours for a 4-engine 10 kW system to more than 29,600 hours for a single-engine 5 kW system. Maximum total impulse values and maximum delta-v's range from 1.2x10(7) to 2.1x10(7) N-s, and 3550 to 6200 m/s, respectively. Maximum available thrusting times for the arcjet propelled spacecraft launched on the DELTA II 6920 vehicle range from approximately 528 hours for the 6-engine 10 kW hydrazine system to 2328 hours for the single-engine 5 kW system. Maximum total impulse values and maximum delta-v's range from 2.2x10(6) to 3.6x10(6) N-s, and approximately 662 to 1072 m/s, respectively.

Electric Propulsion Options for 10 kW Class Earth-Space Missions

Science.gov (United States)

Patterson, M. J.; Curran, Francis M.

1989-01-01

Five and 10 kW ion and arcjet propulsion system options for a near-term space demonstration experiment were evaluated. Analyses were conducted to determine first-order propulsion system performance and system component mass estimates. Overall mission performance of the electric propulsion systems was quantified in terms of the maximum thrusting time, total impulse, and velocity increment capability available when integrated onto a generic spacecraft under fixed mission model assumptions. Maximum available thrusting times for the ion-propelled spacecraft options, launched on a DELTA 2 6920 vehicle, range from approximately 8,600 hours for a 4-engine 10 kW system to more than 29,600 hours for a single-engine 5 kW system. Maximum total impulse values and maximum delta-v's range from 1.2x10 (exp 7) to 2.1x10 (exp 7) N-s, and 3550 to 6200 m/s, respectively. Maximum available thrusting times for the arcjet propelled spacecraft launched on the DELTA 2 6920 vehicle range from approximately 528 hours for the 6-engine 10 kW hydrazine system to 2328 hours for the single-engine 5 kW system. Maximum total impulse values and maximum delta-v's range from 2.2x10 (exp 6) to 3.6x10 (exp 6) N-s, and approximately 662 to 1072 m/s, respectively.

Elastic and inelastic scattering of 800 MeV/c K+- mesons from 12C and 40Ca

International Nuclear Information System (INIS)

Marlow, D.R.

1981-04-01

Methods and results of an experiment to study the scattering of 800 MeV/c K +- mesons from 12 C and 40 Ca are presented. The reactions under study include: the four elastic scattering reactions 12 C(K +- ,K +- ) and 40 Ca(K +- ,K +- ), and the four inelastic scattering reactions, 12 C(K +- .K +- ') to the J/sup P/ = 2 + 4.43 MeV and J/sup P/ = 3 - states. The experimental data were obtained using the Hyper-Nuclear Spectrometer and the Low Energy Separated Beam (LESB I) at the Alternating Gradient Synchrotron (AGS) of Brookhaven Laboratory (BNL). Calculations using the program PIRK, an optical potential code, are compared to the elastic data. The results of a second set of calculations, using Glauber theory are also presented. Both sets of calculations use as input: the results of partial wave analyses of kaon nucleon scattering data, and nuclear shapes as determined from the results of electron nucleus scattering experiments. The agreement between the experimental data and the theoretical predictions is reasonable over the angular range of the data, with the exception of Glauber calculations of the K + elastic scattering. In those cases, the eikonal approximation proves to be a poor approximation. Smaller discrepancies are found in some other cases, indicating the possible need for more sophisticated calculations

Thermodynamics for engineers. Text- and workbook for university students. 2. tot. rev. ed.

International Nuclear Information System (INIS)

Langeheinecke, K.; Sapper, E.

1999-01-01

Technical thermodynamics is part of the basics of engineering. This book lays the foundation needed to understand the real thermal processes. Extensive explanations with a large number of diagrams, examples, problems and exercises illustrate the theory, philosophy, methods and tools of thermodynamics and make this book a valuable instrument of self-study. Specially taken into account is the imparting of technical terminology. The added CDrom presents computer codes for heat transfer, gas-vapor mixtures, combustion and material values, a formula collection THERMODYNAMIK MEMORY and an extensive alphabetic THERMODYNAMIK GLOSSAR. The content in brief: Sytems and their description, material properties, energy, the second fundamental sentence, ideal gases, gas- and gas-vapor-mixtures, heat engines, heat transfer and combustion [de

PI3K-Akt-mTORC1-S6K1/2 Axis Controls Th17 Differentiation by Regulating Gfi1 Expression and Nuclear Translocation of RORγ

Directory of Open Access Journals (Sweden)

Yutaka Kurebayashi

2012-04-01

Full Text Available The PI3K-Akt-mTORC1 axis contributes to the activation, survival, and proliferation of CD4+ T cells upon stimulation through TCR and CD28. Here, we demonstrate that the suppression of this axis by deletion of p85α or PI3K/mTORC1 inhibitors as well as T cell-specific deletion of raptor, an essential component of mTORC1, impairs Th17 differentiation in vitro and in vivo in a S6K1/2-dependent fashion. Inhibition of PI3K-Akt-mTORC1-S6K1 axis impairs the downregulation of Gfi1, a negative regulator of Th17 differentiation. Furthermore, we demonstrate that S6K2, a nuclear counterpart of S6K1, is induced by the PI3K-Akt-mTORC1 axis, binds RORγ, and carries RORγ to the nucleus. These results point toward a pivotal role of PI3K-Akt-mTORC1-S6K1/2 axis in Th17 differentiation.

Path representation of su-hat (2){sub k} states I: Operators and particles for k=1,2

Energy Technology Data Exchange (ETDEWEB)

Lamy-Poirier, Joel, E-mail: jlamypoirier@perimeterinstitute.c [Departement de physique, de genie physique et d' optique, Universite Laval, Quebec, G1K 7P4 (Canada); Mathieu, Pierre, E-mail: pmathieu@phy.ulaval.c [Departement de physique, de genie physique et d' optique, Universite Laval, Quebec, G1K 7P4 (Canada)

2011-04-11

This is the first of two articles devoted to the analysis of the path description of the states in su-hat (2){sub k} WZW models, a representation well suited for constructive derivations of the fermionic characters. In this first article, the cases k=1,2 are treated in detail, emphasizing a different description in each case (operators vs particles). For k=1, we first prove, as a side result, the equivalence of two known path representations for the finitized su-hat (2){sub 1} states by displaying an explicit bijection. An immediate offshoot is the gain of a new and simple weighting for the (Kyoto) path representation that generalizes to level k. The bijection also suggests two operator constructions for the su-hat (2){sub 1} paths, a local and a nonlocal one, both interrelated. These are formal operators that map a path to another path, so that any path can be obtained by successive applications of these operators on a simple reference (ground-state) path. The nonlocal operator description is the starting point for a direct and elementary derivation of the su-hat (2){sub 1} spinon character. The second part presents an extensive study of the su-hat (2){sub 2} paths from their particle point of view, where the particles are defined as the path building blocks. The resulting generating functions appear to provide new (at least superficially) fermionic forms of the characters. In particular, a nice relationship between the sum of the j=0,1 characters at k=2 and the two ones at k=1 is unraveled.

Engineering evaluation of the General Motors (GM) diesel rating and capabilities

Energy Technology Data Exchange (ETDEWEB)

Gross, R.E.

1992-04-01

K-Reactor`s number one GM diesel (GM-lK) suffered recurrent, premature piston pin bushing failures between July 1990 and January 1991. These failures raised a concern that the engine`s original design capabilities were being exceeded. Were we asking old engines to do too much by powering 1200 kw (continuous) rated electrical generators? Was excessive wear of the piston pin bushings a result of having exceeded the engine`s capabilities (overload), or were the recent failures a direct result of poor quality, poor design, or defective replacement parts? Considering the engine`s overall performance for the past 30 years, during which an engine failure of this nature had never occurred, and the fact that 1200 kw was approximately 50% of the engine`s original tested capability, Reactor Engineering did not consider it likely that an overloaded engine caused bushing failures. What seemed more plausible was that the engine`s failure to perform was caused by deficiencies in, or poor quality of, replacement parts.The following report documents: (1) the results of K-Reactor EDG failure analysis; (2) correlation of P- and C-Reactor GM diesel teardowns; (3) the engine rebuild to blueprint specification; (4) how the engine was determined ready for test; (5) testing parameters that were developed; (6) a summary of test results and test insights; (7) how WSRC determined engine operation was acceptable; (8) independent review of 1200 kw operational data; (9) approval of the engines` 12OOkw continuous rating.

K-12 educational outcomes of immigrant youth.

Science.gov (United States)

Crosnoe, Robert; Turley, Ruth N López

2011-01-01

The children from immigrant families in the United States make up a historically diverse population, and they are demonstrating just as much diversity in their experiences in the K-12 educational system. Robert Crosnoe and Ruth López Turley summarize these K-12 patterns, paying special attention to differences in academic functioning across segments of the immigrant population defined by generational status, race and ethnicity, and national origin. A good deal of evidence points to an immigrant advantage in multiple indicators of academic progress, meaning that many youths from immigrant families outperform their peers in school. This apparent advantage is often referred to as the immigrant paradox, in that it occurs despite higher-than-average rates of social and economic disadvantages in this population as a whole. The immigrant paradox, however, is more pronounced among the children of Asian and African immigrants than other groups, and it is stronger for boys than for girls. Furthermore, evidence for the paradox is far more consistent in secondary school than in elementary school. Indeed, school readiness appears to be one area of potential risk for children from immigrant families, especially those of Mexican origin. For many groups, including those from Latin America, any evidence of the immigrant paradox usually emerges after researchers control for family socioeconomic circumstances and youths' English language skills. For others, including those from Asian countries, it is at least partially explained by the tendency for more socioeconomically advantaged residents of those regions to leave their home country for the United States. Bilingualism and strong family ties help to explain immigrant advantages in schooling; school, community, and other contextual disadvantages may suppress these advantages or lead to immigrant risks. Crosnoe and Turley also discuss several policy efforts targeting young people from immigrant families, especially those of Latin

Small atomic displacements in the molybdenophosphates AMo2P3O12 (A = K, Rb, Tl)

International Nuclear Information System (INIS)

Leclaire, A.; Raveau, B.

1988-01-01

KMo 2 P 3 O 12 , M r = 515.90, orthorhombic, Pbnm, a = 17.6398(14), b = 9.1761(4), c = 12.3000(8) A, V = 1990.9(4) A 3 , Z=8, D x = 3.44 Mg m -3 , λ(Mo Kα) = 0.71069 A, μ = 3.42 mm -1 , F(000) = 1952. T = 294 K, R = 0.028 for 2123 reflections. RbMo 2 P 3 O 12 , M r = 562.26, orthorhombic, Pbcm, a = 8.8314(8), b = 9.2368(7), c = 12.3051(9) A, V = 1003.8(4) A 3 , Z=4, D x = 3.72 Mg m -3 , λ(Mo Kα) = 0.71069 A, μ = 8.08 mm -1 , F(000) = 1048, T = 294 K, R = 0.044 for 2073 reflections. The Mo 2 P 3 O 12 frameworks of the K, Rb and Tl compounds are almost the same. The main difference is in the position of the alkaline-earth ions in the tunnels, which induces, in the potassium compound, a superstructure along a. The alkaline-earth ions are slightly displaced as their size decreases in order that the A-O distances may agree with the sum of the ionic radii. (orig.)

A Bibliography of Books Dealing With the Problems of Older Children (Grades 3-12).

Science.gov (United States)

Sacco, Margaret

Books for children that deal with the real problems of children in grades 3 to 12 are listed in this bibliography. The books are concerned with many social problems such as racial inequality, poverty, adult hypocrisy, desertion, broken homes, drugs, alcohol, sex, mental illness, and death. The entries are listed alphabetically by author. Each…

Leading Effective Educational Technology in K-12 School Districts: A Grounded Theory

Science.gov (United States)

Hill, Lara Gillian C.

2011-01-01

A systematic grounded theory qualitative study was conducted investigating the process of effectively leading educational technology in New Jersey public K-12 school districts. Data were collected from educational technology district leaders (whether formal or non-formal administrators) and central administrators through a semi-structured online…

Post secondary project-based learning in science, technology, engineering and mathematics

OpenAIRE

Ralph, Rachel A.

2016-01-01

Project-based learning (PjBL - to distinguish from problem-based learning - PBL) has become a recurrent practice in K-12 classroom environments. As PjBL has become prominent in K-12 classrooms, it has also surfaced in post-secondary institutions.  The purpose of this paper is to examine the research that has studied a variety of science, technology, engineering and mathematic subjects using PjBL in post-secondary classrooms. Eleven articles (including qualitative, quantitative and mixed metho...

Empowered Intersectionality among Black Female K-12 Leaders: A Transcendental Phenomenological Study

Science.gov (United States)

McNeal, Carla

2017-01-01

Black female school leaders remain underrepresented as educational leaders in the K-12 context as marginalizing factors persist in the field. The purpose of this transcendental phenomenological study was to explore the lived experiences of Black female school leaders through the lens of intersectionality. For this research study, intersectionality…

Development of a 400 kV 80 mA Cockcroft-Walton power supply and 12 kW isolation transformer systems for neutron generators

Science.gov (United States)

Lu, X.; Chen, S.; Zhang, Y.; Huang, Z.; Ma, Z.; Yao, Z.

2017-06-01

A 400 kV 80 mA Cockcroft-Walton power supply driven by 2.5 kHz frequency, and 12 kW isolation transformer systems are developed for an intense DD/DT neutron generator. The design, construction, and testing of the high voltage (HV) power supply and isolation transformer systems are detailed reported. The structure of step-up transformers can make the potential distribution uniform, and auxiliary coils of the isolation transformers can improve the power transmission efficiency significantly. The testing results show that the HV power supply can reach 400 kV, and the isolation transformer systems can withstand 400 kV voltages and its power transmission efficiency is about 98.1%.

CESAME: Providing High Quality Professional Development in Science and Mathematics for K-12 Teachers

Science.gov (United States)

Hickman, Paul

2002-04-01

It is appropriate that after almost half a century of Science and Mathematics education reform we take a look back and a peek forward to understand the present state of this wonderfully complex system. Each of the components of this system including teaching, professional development, assessment, content and the district K-12 curriculum all need to work together if we hope to provide quality science, mathematics and technology education for ALL students. How do the state and national standards drive the system? How do state policies on student testing and teacher licensure come into play? How do we improve the preparation, retention and job satisfaction of our K-12 teachers? What initiatives have made or are making a difference? What else needs to be done? What can the physics community do to support local efforts? This job is too big for any single organization or individual but we each can contribute to the effort. Our Center at Northeastern University, with support from the National Science Foundation, has a sharply defined focus: to get high quality, research-based instructional materials into the hands of K-12 classroom teachers and provide the support they need to use the materials effectively in their classrooms.

Impact of Adopt-a-Classroom Partnerships between K-12 and University Faculty

Science.gov (United States)

Smith, Elizabeth; Kindall, Heather D.; Carter, Vinson; Beachner, Maggie

2016-01-01

There is often a disconnect between K-12 schools and postsecondary institutions. While this gap has grown consistently, the need for collaboration between systems is greater than ever. The Adopt-A-Classroom program was created to address the need for greater university faculty involvement in public schools by providing opportunities for…

Measurement Invariance of the "Servant Leadership Questionnaire" across K-12 Principal Gender

Science.gov (United States)

Xu, Lihua; Stewart, Trae; Haber-Curran, Paige

2015-01-01

Measurement invariance of the five-factor "Servant Leadership Questionnaire" between female and male K-12 principals was tested using multi-group confirmatory factor analysis. A sample of 956 principals (56.9% were females and 43.1% were males) was analysed in this study. The hierarchical multi-step measurement invariance test supported…

12 MeV, 4.3 kW electron linear accelerator irradiation application

International Nuclear Information System (INIS)

Hang Desheng; Lai Qiji

2000-01-01

Characteristics of an electron linear accelerator, which has 6-12 MeV energy, 4.2 kW average beam power is introduced. Results show that it has advantages on improving the characteristics of semiconductor devices such as diodes, triodes, SCR, preventing garlic from sprout, preservation of food, and so on

The Influence of Lean on K-12 District Management: A Case Study

Science.gov (United States)

Brown, Beverly

2011-01-01

For decades, policymakers and educators have focused on public school equity and adequacy, while paying little attention to efficiency. This qualitative single case study was designed to capture explicit information about Lean management, operations, and culture in a K-12 Michigan school district engaged in Lean training and implementation for a…

After 60 Years, Do the Arguments for K-12 Vouchers Still Hold?

Science.gov (United States)

Laitsch, Dan

2016-01-01

In 1955, Milton Friedman authored a foundational paper proposing a shift in funding and governance mechanisms for public K-12 schools, suggesting that parents be awarded tuition vouchers that they could use to pay for private sector education services for their children, rather than relying on government provided neighborhood schools. Friedman…

Ecological optimization of an irreversible quantum Carnot heat engine with spin-1/2 systems

International Nuclear Information System (INIS)

Liu Xiaowei; Chen Lingen; Wu Feng; Sun Fengrui

2010-01-01

A model of a quantum heat engine with heat resistance, internal irreversibility and heat leakage and many non-interacting spin-1/2 systems is established in this paper. The quantum heat engine cycle is composed of two isothermal processes and two irreversible adiabatic processes and is referred to as a spin quantum Carnot heat engine. Based on the quantum master equation and the semi-group approach, equations of some important performance parameters, such as power output, efficiency, entropy generation rate and ecological function (a criterion representing the optimal compromise between exergy output rate and exergy loss rate), for the irreversible spin quantum Carnot heat engine are derived. The optimal ecological performance of the heat engine in the classical limit is analyzed with numerical examples. The effects of internal irreversibility and heat leakage on ecological performance are discussed in detail.

Performance of a single nutating disk engine in the 2 to 500 kW power range

International Nuclear Information System (INIS)

Korakianitis, T.; Boruta, M.; Jerovsek, J.; Meitner, P.L.

2009-01-01

A new type of internal combustion engine with distinct advantages over conventional piston-engines and gas turbines in small power ranges is presented. The engine has analogies with piston engine operation, but like gas turbines it has dedicated spaces and devices for compression, burning and expansion. The engine operates on a modified limited-pressure thermodynamic cycle. The core of the engine is a nutating non-rotating disk, with the center of its hub mounted in the middle of a Z-shaped shaft. The two ends of the shaft rotate, while the disk nutates. The motion of the disk circumference prescribes a portion of a sphere. In the single-disk configuration a portion of the surface area of the disk is used for intake and compression, a portion is used to seal against a center casing, and the remaining portion is used for expansion and exhaust. The compressed air is admitted to an external accumulator, and then into an external combustion chamber before it is admitted to the power side of the disk. The external combustion chamber enables the engine to operate on a variable compression ratio cycle. Variations in cycle temperature ratio and compression ratio during normal operation enable the engine to effectively become a variable-cycle engine, allowing significant flexibility for optimizing efficiency or power output. The thermal efficiency is similar to that of medium sized diesel engines. For the same engine volume and weight this engine produces approximately twice the power of a two-stroke engine and four times the power of a four-stroke engine. The computed sea-level engine performance at design and off-design conditions in the 2 to 500 kW power range is presented.

Cryogenic laboratory (80 K - 4 K)

International Nuclear Information System (INIS)

Brad, Sebastian; Steflea, Dumitru

2002-01-01

The technology of low temperature at the beginning of this century, developed for the production of oxygen, nitrogen and rare gases, was the basis for setting up the cryogenic technology in all the companies with these activity fields. The cryogenics section of today comprises engineering and construction of cryogenic plants for science, research and development, space technology, nuclear power techniques. Linde has designed and built a reliable small scale Helium liquefier. This fully automatic cryoliquefier operates for purification, liquefaction as well as re-liquefaction of Helium-gas, evaporated in cryostat systems. The basic equipment of the Linde L5 are the liquefier apparatus, transfer line, medium pressure buffer vessel, automatic purifier, compressor with mechanical oil separation unit, oil adsorber, electrical control unit. The accessories of the Linde L5 are the liquid helium storage tank, high-pressure gas supply, helium recovery unit, and cryocomponents. The cycle compressor C 101 designed as a single stage screw compressor supplies the liquefaction process with approx. 10 g/s of helium at a pressure of 10 to 12 bar and a temperature of approx. 300 K. In the first plate heat exchanger E 201 the gas is cooled down to approx. 70 K. Then the He high-pressure flow is divided: about 7 g/s reach the turbine X 201 via valve 203 (turbine entry) and are expanded there to approx. 4.6 bar, the gas cooling down to 64 K. After further cooling in the heat exchanger E 203 to about 16 K, another power-consuming expansion to 1.2 bar takes place. The implied cooling of the gas results in a temperature of 12 K at the outlet of the turbine X 202. This gas is then transferred to the low-pressure side of the heat exchanger E 204. The smaller part of the He high-pressure gas flow (approx. 3 g/s) is cooled down in the heat exchanger E 202 - E 205 to about 7 K. One part of the cold helium gas (approx. 0.17 g/s) is used in the purifier to cool down the feed gas to air

Sodium--NaK engineering handbook. Volume IV. Sodium pumps, valves, piping, and auxiliary equipment

International Nuclear Information System (INIS)

Foust, O.J.

1978-01-01

The handbook is useful for designers in the Liquid Metals Fast Breeder Reactor (LMFBR) program and by the engineering and scientific community performing investigation and experimentation requiring high-temperature Na and NaK technology. Data are presented for pumps, bearings and seals, valves, vessels and piping, and auxiliary equipment including vapor traps, freeze plugs, fuel-channel flow regulators, antivortexing devices, and miscellaneous mechanical elements. Reactor materials are also discussed

How to Get Successfully Involved with K-12 Education

Science.gov (United States)

Duncan, D.; Fraknoi, A.; Bennett, M.

1998-05-01

Many astronomers now have some involvement in K-12 education, either through their children, through large projects with an education or outreach office, or through an educational component to their own grants. Some may need to incorporate education components into future proposals. For those new to education, it can be difficult to decide how best to use their limited resources without "re-inventing the wheel." Some astronomers are comfortable taking a direct role in the classroom or working with teachers, others prefer developing web-based or printed materials, while still others wouldrather work with local schools of education to enhance the training of future teachers. Which of these roles is most useful? In this session, participants will learn what has worked well in the past, with special attention paid to ways in which astronomers' and physicists' training and instincts may fail them when working in education. Invited teachers will describe their classrooms and how astronomers can be most helpful to them. Sample (successful) activities will be demonstrated, and information given about the wide range of existing astronomy and space-science education programs around the country. A full menu of useful ways that astronomers can get involved will be presented, as well as the organizations and institutions which can help in devising a meaningful education program. Handouts will include a catalog of national astronomy education projects, a list of educational web sites, information about the NASA OSS education brokers and facilitators, examples of successful educational materials, and a listing of roles astronomers have played or could play to enhance K-12 education. Registration is required; see the AAS Education WWW page or email aased@aas.org.

Explaining Technology Integration in K-12 Classrooms: A Multilevel Path Analysis Model

Science.gov (United States)

Liu, Feng; Ritzhaupt, Albert D.; Dawson, Kara; Barron, Ann E.

2017-01-01

The purpose of this research was to design and test a model of classroom technology integration in the context of K-12 schools. The proposed multilevel path analysis model includes teacher, contextual, and school related variables on a teacher's use of technology and confidence and comfort using technology as mediators of classroom technology…

Addressing the NETS*S in K-12 Classrooms: Implications for Teacher Education

Science.gov (United States)

Niederhauser, Dale S.; Lindstrom, Denise L.; Strobel, Johannes

2007-01-01

The National Educational Technology Standards for Students (NETS*S) were developed to provide guidelines for effective and meaningful technology use with K-12 students. In the present study we used the NETS*S as a framework to analyze ways that teachers integrated instructional technology use and provided opportunities for their students to…

California K-12 Schools and Communities Collaborate to Support Student Mental Health

Science.gov (United States)

Woodbridge, Michelle W.; Goldweber, Asha; Yu, Jennifer; Golan, Shari; Stein, Bradley D.

2013-01-01

Across the education, public health, and human and social services areas, there is renewed interest in bringing agency representatives together to work on the promotion of student mental health and wellness. One of the aims of California's Prevention and Early Intervention (PEI) K-12 Student Mental Health (SMH) initiative funded under Proposition…

What Is (Or Should Be) Scientific Evidence Use in K-12 Classrooms?

Science.gov (United States)

McNeill, Katherine L.; Berland, Leema

2017-01-01

Research and reform efforts frequently identify evidence as an essential component of science classroom instruction to actively engage students in science practices. Despite this agreement on the primacy of evidence, there is a lack of consensus around what counts as "evidence" in k-12 classrooms (e.g., ages 5-18): scholarship and…

NAGC Pre-K-Grade 12 Gifted Education Programming Standards: A Guide to Planning and Implementing High-Quality Services

Science.gov (United States)

Johnsen, Susan K., Ed.

2012-01-01

The new Pre-K-Grade 12 Gifted Education Programming Standards should be part of every school district's repertoire of standards to ensure that the learning needs of advanced students are being met. "NAGC Pre-K-Grade 12 Gifted Education Programming Standards: A Guide to Planning and Implementing High-Quality Services" details six standards that…

Engineering evaluation of the General Motors (GM) diesel rating and capabilities

International Nuclear Information System (INIS)

Gross, R.E.

1992-04-01

K-Reactor's number one GM diesel (GM-lK) suffered recurrent, premature piston pin bushing failures between July 1990 and January 1991. These failures raised a concern that the engine's original design capabilities were being exceeded. Were we asking old engines to do too much by powering 1200 kw (continuous) rated electrical generators? Was excessive wear of the piston pin bushings a result of having exceeded the engine's capabilities (overload), or were the recent failures a direct result of poor quality, poor design, or defective replacement parts? Considering the engine's overall performance for the past 30 years, during which an engine failure of this nature had never occurred, and the fact that 1200 kw was approximately 50% of the engine's original tested capability, Reactor Engineering did not consider it likely that an overloaded engine caused bushing failures. What seemed more plausible was that the engine's failure to perform was caused by deficiencies in, or poor quality of, replacement parts.The following report documents: (1) the results of K-Reactor EDG failure analysis; (2) correlation of P- and C-Reactor GM diesel teardowns; (3) the engine rebuild to blueprint specification; (4) how the engine was determined ready for test; (5) testing parameters that were developed; (6) a summary of test results and test insights; (7) how WSRC determined engine operation was acceptable; (8) independent review of 1200 kw operational data; (9) approval of the engines' 12OOkw continuous rating

Genetic Engineering of T Cells to Target HERV-K, an Ancient Retrovirus on Melanoma.

Science.gov (United States)

Krishnamurthy, Janani; Rabinovich, Brian A; Mi, Tiejuan; Switzer, Kirsten C; Olivares, Simon; Maiti, Sourindra N; Plummer, Joshua B; Singh, Harjeet; Kumaresan, Pappanaicken R; Huls, Helen M; Wang-Johanning, Feng; Cooper, Laurence J N

2015-07-15

The human endogenous retrovirus (HERV-K) envelope (env) protein is a tumor-associated antigen (TAA) expressed on melanoma but not normal cells. This study was designed to engineer a chimeric antigen receptor (CAR) on T-cell surface, such that they target tumors in advanced stages of melanoma. Expression of HERV-K protein was analyzed in 220 melanoma samples (with various stages of disease) and 139 normal organ donor tissues using immunohistochemical (IHC) analysis. HERV-K env-specific CAR derived from mouse monoclonal antibody was introduced into T cells using the transposon-based Sleeping Beauty (SB) system. HERV-K env-specific CAR(+) T cells were expanded ex vivo on activating and propagating cells (AaPC) and characterized for CAR expression and specificity. This includes evaluating the HERV-K-specific CAR(+) T cells for their ability to kill A375-SM metastasized tumors in a mouse xenograft model. We detected HERV-K env protein on melanoma but not in normal tissues. After electroporation of T cells and selection on HERV-K(+) AaPC, more than 95% of genetically modified T cells expressed the CAR with an effector memory phenotype and lysed HERV-K env(+) tumor targets in an antigen-specific manner. Even though there is apparent shedding of this TAA from tumor cells that can be recognized by HERV-K env-specific CAR(+) T cells, we observed a significant antitumor effect. Adoptive cellular immunotherapy with HERV-K env-specific CAR(+) T cells represents a clinically appealing treatment strategy for advanced-stage melanoma and provides an approach for targeting this TAA on other solid tumors. ©2015 American Association for Cancer Research.

New 5 kW free-piston Stirling space convertor developments

Science.gov (United States)

Brandhorst, Henry W., Jr.; Chapman, Peter A., Jr.

2008-07-01

The NASA Vision for Exploration of the moon may someday require a nuclear reactor coupled with a free-piston Stirling convertor at a power level of 30-40 kW. In the 1990s, Mechanical Technology Inc.'s Stirling Engine Systems Division (some of whose Stirling personnel are now at Foster-Miller, Inc.) developed a 25 kW free-piston Stirling Space Power Demonstrator Engine under the SP-100 program. This system consisted of two 12.5 kW engines connected at their hot ends and mounted in tandem to cancel vibration. Recently, NASA and DoE have been developing dual 55 and 80 W Stirling convertor systems for potential use with radioisotope heat sources. Total test times of all convertors in this effort exceed 120,000 h. Recently, NASA began a new project with Auburn University to develop a 5 kW, single convertor for potential use in a lunar surface reactor power system. Goals of this development program include a specific power in excess of 140 W/kg at the convertor level, lifetime in excess of five years and a control system that will safely manage the convertors in case of an emergency. Auburn University awarded a subcontract to Foster-Miller, Inc. to undertake development of the 5 kW Stirling convertor assembly. The characteristics of the design along with progress in developing the system will be described.

Factors Influencing the Self-Efficacy of Black High School Students Enrolled in PLTW Pre-Engineering Courses

Science.gov (United States)

Martin, Brandon R.

2011-01-01

With the increasing demand for trained engineers (especially Black engineers) it is imperative that the US invests more money and resources into programs that provide quality engineering experiences and exposures, this study evaluates the effect of various K-12 outreach initiatives and their ability to inspire students enrolled in Project Lead the…

Participative Teaching with Mobile Devices and Social Networks for K-12 Children

Directory of Open Access Journals (Sweden)

Livia Stefan

2016-08-01

Full Text Available This article details a set of participatory pedagogical experiments conducted within a research grant PN II IDEI (”Time Maps. Real communities, virtual worlds, experimented pasts” performed with the purpose of helping rural communities in identifying their cultural heritage andtransmitting it to the younger generations by means of modern IT technologies, including web 2.0. In a Danubian rural community, several points of archaeological interest (POIs were identified, which were then included in a geographic Augmented Reality application for smartphones and tablets. Subsequently, the geographic data were collected from the archaeological site by the K-12 children, under the coordination of an academic staff member of the National University of Arts in Bucharest, and stored on their devices using Google Maps. The augmented information provided onthe site was annotated and shared with other K-12 children, through different social networks sites (SNS and content postings. This first stage experiment was extended to the development of a social learning environment complementary to the educational site (www.timemaps.net to support thetransmission of several traditional technologies (textile, ceramic, glass in a collaborative manner. We consider that our experiments can significantly increase the visibility of the information pertaining to the identity of target places and communities among the younger generation. A mobile-learning paradigm, in combination with web 2.0 technologies, was the support for a distributed and low-cost platform for communication and collaboration. Social networks linked thearchaeological heritage and the academic research with the larger community of rural K-12 children. The article analyzes this platform as a solution for creating, collecting and sharingeducational content, and presents conclusions on using social media for effective blended learning and transmittal of the cultural heritage.

An Empirical Evaluation of Distance Learning's Effectiveness in the K-12 Setting

Science.gov (United States)

Harris-Packer, Jerilyn D.; Ségol, Geneviève

2015-01-01

This study evaluated the effect of online instruction on the academic achievement of K--12 students in ten states as measured by the percentage of proficient students in reading and mathematics at the school level. We used publicly available data provided by the Department of Education in Florida, Michigan, Minnesota, Nevada, Ohio, Pennsylvania,…

Exemplar: A Model for Social Studies Curriculum Development in Delaware, K-12.

Science.gov (United States)

Delaware State Dept. of Public Instruction, Dover.

GRADES OR AGES: Grades K-12. SUBJECT MATTER: Social studies. ORGANIZATION AND PHYSICAL APPEARANCE: The subject matter is divided into the following five themes: 1) Man develops within his physical and cultural environment. 2) Man functions within an interdependent society. 3) Man seeks justice and order. 4) Man experiences conflict and change. 5)…

Peer Mentoring and Peer Tutoring among K-12 Students: A Literature Review

Science.gov (United States)

Goodrich, Andrew

2018-01-01

The purpose of this literature review is to examine research on peer mentoring among K-12 students to assist practitioners with how to incorporate these instructional techniques into their own music programs. Primary themes across the music education literature of peer mentoring include the role of music teachers, the role of students as they…

Standards Based Design: Teaching K-12 Educators to Build Quality Online Courses

Science.gov (United States)

Quiroz, René E.; Ritter, Nicola L.; Li, Yun; Newton, Rhonda C.; Palkar, Trupti

2016-01-01

The number of online courses, programs, and schools are growing exponentially in K-12 education. Given the unique nature of online courses and the distinct skills necessary to create a quality online course, it is essential that effective professional development be provided for teachers designing online courses. Online courses need to be of the…

Effects of Mobile Devices on K-12 Students' Achievement: A Meta-Analysis

Science.gov (United States)

Tingir, S.; Cavlazoglu, B.; Caliskan, O.; Koklu, O.; Intepe-Tingir, S.

2017-01-01

In this meta-analytic study, we investigated the effects of mobile devices on student achievement in science, mathematics and reading in grades K-12. Based on our inclusion criteria, we searched the ERIC and PsycINFO databases and identified 14 peer-reviewed research articles published between 2010 and 2014. We identified the device type, subject…

Bearing development program for a 25 kWe solar-powered organic Rankine-cycle engine

Science.gov (United States)

Nesmith, B.

1985-01-01

The bearing development program is summarized for a 25-kWe power conversion subsystem (PCS) consisting of an organic Rankine-cycle engine, and permanent magnetic alternator (PMA) and rectifier to be used in a 100-kWe point-focusing distributed receiver solar power plant. The engine and alternator were hermetically sealed and used toluene as the working fluid. The turbine, alternator, and feed pump (TAP) were mounted on a single shaft operating at speeds up to 60,000 rev/min. Net thermal-to-electric efficiencies in the range of 21 to 23% were demonstrated at the maximum working fluid temperature of 400 C (750 F). A chronological summary of the bearing development program is presented. The primary causes of bearing wear problems were traced to a combination of rotordynamic instability and electrodynamic discharge across the bearing surfaces caused by recirculating currents from the PMA. These problems were resolved by implementing an externally supplied, flooded-bearing lubrication system and by electrically insulating all bearings from the TAP housing. This program resulted in the successful development of a stable, high-speed, toluene-lubricated five-pad tilting-pad journal bearing and Rayleigh step thrust bearing system capable of operating at all inclinations between horizontal and vertical.

Environmental Education and K-12 Student Outcomes: A Review and Analysis of Research

Science.gov (United States)

Ardoin, Nicole M.; Bowers, Alison W.; Roth, Noelle Wyman; Holthuis, Nicole

2018-01-01

Many practitioners and researchers describe academic and environmental benefits of environmental education for kindergarten through twelfth grade (K-12) students. To consider the empirical underpinnings of those program descriptions, we systematically analyzed the peer-reviewed literature (1994-2013), focusing on outcomes of environmental…

Engineering a cyanobacterium as the catalyst for the photosynthetic conversion of CO2 to 1,2-propanediol

Directory of Open Access Journals (Sweden)

Li Han

2013-01-01

Full Text Available Abstract Background The modern society primarily relies on petroleum and natural gas for the production of fuels and chemicals. One of the major commodity chemicals 1,2-propanediol (1,2-PDO, which has an annual production of more than 0.5 million tons in the United States, is currently produced by chemical processes from petroleum derived propylene oxide, which is energy intensive and not sustainable. In this study, we sought to achieve photosynthetic production of 1,2-PDO from CO2 using a genetically engineered cyanobacterium Synechococcus elongatus PCC 7942. Compared to the previously reported biological 1,2-PDO production processes which used sugar or glycerol as the substrates, direct chemical production from CO2 in photosynthetic organisms recycles the atmospheric CO2 and will not compete with food crops for arable land. Results In this study, we reported photosynthetic production of 1,2-PDO from CO2 using a genetically engineered cyanobacterium Synechococcus elongatus PCC 7942. Introduction of the genes encoding methylglyoxal synthase (mgsA, glycerol dehydrogenase (gldA, and aldehyde reductase (yqhD resulted in the production of ~22mg/L 1,2-PDO from CO2. However, a comparable amount of the pathway intermediate acetol was also produced, especially during the stationary phase. The production of 1,2-PDO requires a robust input of reducing equivalents from cellular metabolism. To take advantage of cyanobacteria’s NADPH pool, the synthetic pathway of 1,2-PDO was engineered to be NADPH-dependent by exploiting the NADPH-specific secondary alcohol dehydrogenases which have not been reported for 1,2-PDO production previously. This optimization strategy resulted in the production of ~150mg/L 1,2-PDO and minimized the accumulation of the incomplete reduction product, acetol. Conclusion This work demonstrated that cyanobacteria can be engineered as a catalyst for the photosynthetic conversion of CO2 to 1,2-PDO. This work also characterized two NADPH

Assessment Strategies for Implementing Ngss in K12 Earth System Science Classrooms

Science.gov (United States)

McAuliffe, C.

2016-12-01

Several science education researchers have led assessment efforts that provide strategies particularly useful for evaluating the threedimensional learning that is central to NGSS (DeBarger, A. H., Penuel, W. R., Harris, C. J., Kennedy, C. K., 2016; Knight, A. M. & McNeill, K. L., 2015; McNeill, K. L., KatshSinger, R. & Pelletier, P., 2015; McNeill K.L., et.al., 2015; McNeill, K.L., & Krajcik, J.S., 2011; Penuel, W., 2016). One of the basic premises of these researchers is that, "Assessment is a practice of argument from evidence based on what students say, do, and write" and that "the classroom is the richest place to gather evidence of what students know (Penuel, W., 2016). The implementation of the NGSS in Earth System Science provides a unique opportunity for geoscience education researchers to study student learning and contribute to the development of this research as well as for geoscience educators to apply these approaches and strategies in their own work with K12 inservice and preservice educators. DeBarger, A. H., Penuel, W. R., Harris, C. J., Kennedy, C. K. (2016). Building an Assessment Argument to Design and Use Next Generation Science Assessments in Efficacy Studies of Curriculum Interventions. American†Journal†of†Evaluation†37(2) 174192Æ Knight, A. M. & McNeill, K. L. (2015). Comparing students' individual written and collaborative oral socioscientific arguments. International Journal of Environmental and Science Education.10(5), 23647. McNeill, K. L., KatshSinger, R. & Pelletier, P. (2015). Assessing science practices-Moving your class along a continuum. Science Scope. McNeill, K.L., & Krajcik, J.S. (2011). Supporting Grade 5-8 Students in Constructing Explanations in Science: The Claim, Evidence, and Reasoning Framework for Talk and Writing. Upper Saddle River, New Jersey: Pearson. Penuel, W. (2016). Classroom Assessment Strategies for NGSS Earth and Space Sciences. Implementing†the†NGSS†Webinar†Series, February 11, 2016.

I12: the Joint Engineering, Environment and Processing (JEEP) beamline at Diamond Light Source

International Nuclear Information System (INIS)

Drakopoulos, Michael; Connolley, Thomas; Reinhard, Christina; Atwood, Robert; Magdysyuk, Oxana; Vo, Nghia; Hart, Michael; Connor, Leigh; Humphreys, Bob; Howell, George; Davies, Steve; Hill, Tim; Wilkin, Guy; Pedersen, Ulrik; Foster, Andrew; De Maio, Nicoletta; Basham, Mark; Yuan, Fajin; Wanelik, Kaz

2015-01-01

JEEP is a high-energy (50–150 keV) multi-purpose beamline offering polychromatic and monochromatic modes. It can accommodate large samples and experimental rigs, enabling in situ studies using radiography, tomography, energy-dispersive diffraction, monochromatic and white-beam two-dimensional diffraction/scattering and small-angle X-ray scattering. I12 is the Joint Engineering, Environmental and Processing (JEEP) beamline, constructed during Phase II of the Diamond Light Source. I12 is located on a short (5 m) straight section of the Diamond storage ring and uses a 4.2 T superconducting wiggler to provide polychromatic and monochromatic X-rays in the energy range 50–150 keV. The beam energy enables good penetration through large or dense samples, combined with a large beam size (1 mrad horizontally × 0.3 mrad vertically). The beam characteristics permit the study of materials and processes inside environmental chambers without unacceptable attenuation of the beam and without the need to use sample sizes which are atypically small for the process under study. X-ray techniques available to users are radiography, tomography, energy-dispersive diffraction, monochromatic and white-beam two-dimensional diffraction/scattering and small-angle X-ray scattering. Since commencing operations in November 2009, I12 has established a broad user community in materials science and processing, chemical processing, biomedical engineering, civil engineering, environmental science, palaeontology and physics

Phleomycin-induced lethality and DNA degradation in Escherichia coli K12

Energy Technology Data Exchange (ETDEWEB)

Nakayama, H

1975-01-01

The cell lethality and DNA fragmentation caused by phleomycin (PM) were studied in E. coli K12 strains with special reference to the effects of repair or recombination deficiencies and metabolic inhibitors. Unlike excision-defective derivatives of E. coli B, uvrA, uvrB, and uvrC mutants of strain K12 showed no peculiarities compared with wild type in regard to cell survival. Likewise, mutant alleles at uvrD and polA loci had no effect. In contrast, rec mutants were more sensitive to PM-killing than were rec/sup +/ strains. PM-induced strand breakage in DNA was observed in all strains tested including the above-mentioned mutants. There was no significant distinction between the uvr mutants and the wild type strain, indicating that the uvr-endonuclease was not responsible for the strand breaks. Involvement of endonuclease I was also ruled out. At least some of the PM-induced strand breaks were repairable. PM-induced lethality and strand breakage were totally dependent on energy supply. Inhibition of protein synthesis resulted in a partial and parallel suppression of the two effects. Our results suggest that the lethality is due to DNA strand breakage and the repair of such damage is postulated to be controlled by rec genes.

Advanced Energy Retrofit Guide: Practical Ways to Improve Energy Performance, K-12 Schools (Book)

Energy Technology Data Exchange (ETDEWEB)

2013-12-01

The U.S. Department of Energy developed the Advanced Energy Retrofit Guides (AERGs) to provide specific methodologies, information, and guidance to help energy managers and other stakeholders plan and execute energy efficiency improvements. Detailed technical discussion is fairly limited. Instead, we emphasize actionable information, practical methodologies, diverse case studies, and unbiased evaluations of the most promising retrofit energy efficiency measures for each building type. A series of AERGs is under development, addressing key segments of the commercial building stock. K-12 schools were selected as one of the highest priority building sectors, because schools affect the lives of most Americans. They also represent approximately 8% of the energy use and 10% of the floor area in commercial buildings nationwide. U.S. K-12 school districts spend more than $8 billion each year on energy - more than they spend on computers and textbooks combined. Most occupy older buildings that often have poor operational performance - more than 30% of schools were built before 1960. The average age of a school is about 42 years - which is nearly the expected serviceable lifespan of the building. K-12 schools offer unique opportunities for deep, cost-effective energy efficiency improvements, and this guide provides convenient and practical guidance for exploiting these opportunities in the context of public, private, and parochial schools.

Analysis of 3D Modeling Software Usage Patterns for K-12 Students

Science.gov (United States)

Wu, Yi-Chieh; Liao, Wen-Hung; Chi, Ming-Te; Li, Tsai-Yen

2016-01-01

In response to the recent trend in maker movement, teachers are learning 3D techniques actively and bringing 3D printing into the classroom to enhance variety and creativity in designing lectures. This study investigates the usage pattern of a 3D modeling software, Qmodel Creator, which is targeted at K-12 students. User logs containing…

Jumping the PBL Implementation Hurdle: Supporting the Efforts of K-12 Teachers

Science.gov (United States)

Ertmer, Peggy A.; Simons, Krista D.

2006-01-01

While problem-based learning (PBL) has a relatively long history of successful use in medical and pre-professional schools, it has yet to be widely adopted by K--12 teachers. This may be due, in part, to the numerous challenges teachers experience when implementing PBL. In this paper, we describe specific hurdles that teachers are likely to…

iPads in K-12 Schools: A Grounded Theory Study of Value

Science.gov (United States)

Townsend, Mary Beth

2017-01-01

This qualitative grounded theory study investigated the value of iPads in K-12 schools when used in one-to-one ratios. The purpose of the study was to understand the perspectives of teachers using iPads in one-to-one ratios for teaching and learning in the classroom and administrators responsible for the implementation of these devices. The…

Problem-Based Learning in the Earth and Space Science Classroom, K-12

Science.gov (United States)

McConnell, Tom J.; Parker, Joyce; Eberhardt, Janet

2017-01-01

If you've ever asked yourself whether problem-based learning (PBL) can bring new life to both your teaching and your students' learning, here's your answer: Yes. This all-in-one guide will help you engage your students in scenarios that represent real-world science in all its messy, thought-provoking glory. The scenarios will prompt K-12 students…

Integrating the iPod Touch in K-12 Education: Visions and Vices

Science.gov (United States)

Banister, Savilla

2010-01-01

Advocates of ubiquitous computing have long been documenting classroom benefits of one-to-one ratios of students to handheld or laptop computers. The recent sophisticated capabilities of the iPod Touch, iPhone, and iPad have encouraged further speculation on exactly how K-12 teaching and learning might be energized by such devices. This paper…

Code to Learn: Where Does It Belong in the K-12 Curriculum?

Science.gov (United States)

Moreno-León, Jesús; Robles, Gregorio; Román-González, Marcos

2016-01-01

The introduction of computer programming in K-12 has become mainstream in the last years, as countries around the world are making coding part of their curriculum. Nevertheless, there is a lack of empirical studies that investigate how learning to program at an early age affects other school subjects. In this regard, this paper compares three…

Enrichment Experiences in Engineering (E[superscript 3]) for Teachers Summer Research Program: An Examination of Mixed-Method Evaluation Findings on High School Teacher Implementation of Engineering Content in High School STEM Classrooms

Science.gov (United States)

Page, Cheryl A.; Lewis, Chance W.; Autenrieth, Robin L.; Butler-Purry, Karen L.

2013-01-01

Ongoing efforts across the U.S. to encourage K-12 students to consider science, technology, engineering and mathematics (STEM) careers have been motivated by concerns that the STEM pipeline is shrinking because of declining student enrollment and increasing rates of retirement in industry. The Enrichment Experiences in Engineering (E[superscript…

Summaries of FY 1997 engineering research

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-09-01

This report documents the Basic Energy Sciences (BES) Engineering Research Program for fiscal year 1997, it provides a summary for each of the program projects in addition to a brief program overview. The report is intended to provide staff of Congressional committees, other executive departments, and other DOE offices with substantive program information so as to facilitate governmental overview and coordination of Federal research programs. Of equal importance, its availability facilitates communication of program information to interested research engineers and scientists. The individual project summaries follow the program overview. The summaries are ordered alphabetically by name of institution; the table of contents lists all the institutions at which projects were sponsored in fiscal year 1997. Each project entry begins with an institutional-departmental heading. The names of investigators are listed immediately below the title. The funding level for fiscal year 1997 appears to the right of address. The summary description of the project completes the entry. A separate index of Principal Investigators includes phone number, fax number and e-main address, where available.

The Effectiveness of Educational Technology Applications for Enhancing Mathematics Achievement in K-12 Classrooms: A Meta-Analysis. Educator's Summary

Science.gov (United States)

Center for Research and Reform in Education, 2012

2012-01-01

This review summarizes research on the effects of technology use on mathematics achievement in K-12 classrooms. The main research questions included: (1) Do education technology applications improve mathematics achievement in K-12 classrooms as compared to traditional teaching methods without education technology?; and (2) What study and research…

Green and facile synthesis of graphene nanosheets/K{sub 3}PW{sub 12}O{sub 40} nanocomposites with enhanced photocatalytic activities

Energy Technology Data Exchange (ETDEWEB)

Yang, Hongxun, E-mail: yhongxun@126.com [School of Environmental & Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang 212003 (China); State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fujian, Fuzhou 350002 (China); Liu, Xiaoyan; Sun, Shengnan; Nie, Yu; Wu, Huipeng; Yang, Tongyi; Zheng, Shaojun [School of Environmental & Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang 212003 (China); Lin, Shengling, E-mail: linshl5757@sina.com [School of Environmental & Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang 212003 (China)

2016-06-15

Highlights: • A new graphene/K{sub 3}PW{sub 12}O{sub 40} (GPW) composite was synthesized via photoreduction method. • Graphene in the GPW could reduce the recombination of electron-hole pairs. • Graphene in the GPW could increase adsorptive property. • GPW hybrid shows an enhancement photocatalytic activity. - Abstract: K{sub 3}PW{sub 12}O{sub 40} is a promising polyoxometalate photocatalyst for the removal of organic pollutants from water. However, two main disadvantages of poor adsorptive performance and high recombination rate of photogenerated electron-hole pair hinder its practical applications. In this paper, a new graphene nanosheets/K{sub 3}PW{sub 12}O{sub 40} nanocomposite has been synthesized via a green photoreduction strategy, being low-cost and scalable production. Characterizations show that K{sub 3}PW{sub 12}O{sub 40} nanoparticles with 60 nm or so have been successfully deposited on the graphene nanosheets. As a kind of photocatalyst, the binary graphene nanosheets/K{sub 3}PW{sub 12}O{sub 40} nanocomposite displays improved photocatalytic activity compared to pure K{sub 3}PW{sub 12}O{sub 40}. This improvement is ascribed to the introduction of graphene nanosheets in the nanocomposite, which could increase adsorptive property and reduce the recombination of electron-hole pairs.

Introducing Engineering in Elementary Education: A 5-Year Study of Teachers and Students

Science.gov (United States)

Diefes-Dux, Heidi A.

2015-01-01

Engineering, when integrated into K-12 education, may offer a number of potential student learning and future success benefits. In a 5-year study, four cohorts of elementary teachers of grades 2 to 4 in a single US school district were provided with teacher professional development with engineering education. Teachers were prepared to teach…

Cataclysms and Catastrophes: A Case Study of Improving K-12 Science Education Through a University Partnership

Science.gov (United States)

Fennell, T.; Ellins, K. K.; Morris, M.; Christeson, G.

2003-12-01

The K-12 science teacher is always seeking ways of improving and updating their curriculum by integrating the latest research into their most effective classroom activities. However, the daily demands of delivering instruction to large numbers of students coupled with the rapid advances in some fields of science can often overwhelm this effort. The NSF-sponsored Cataclysms and Catastrophes curriculum, developed by scientists from the The University of Texas at Austin Institute for Geophysics (UTIG) and Bureau of Economic Geology (BEG), middle and high school teachers, and UT graduate students (NSF GK-12 fellows) working together through the GK-12 program, is a textbook example of how universities can facilitate this quest, benefiting education at both K-12 and university levels. In 1992, "The Great K-T Extinction Debate" was developed as an activity in the Planet Earth class at the Liberal Arts and Science Academy of Austin as an interdisciplinary approach to science. Taking advantage of the media attention generated by the impact scenario for the K-T extinction, the activity consists of students participating in a simulated senate hearing on the potential causes of the K-T extinction and their implications for society today. This activity not only exposes students to the wide range of science involved in understanding mass extinctions, but also to the social, political and economic implications when this science is brought into the public arena and the corresponding use of data in decision making and disaster preparedness. While "The Great K-T Extinction Debate" was always a popular and effective activity with students, it was in desperate need of updating to keep pace with the evolving scientific debate over the cause of the K-T extinction and the growing body of impact evidence discovered over the past decade. By adding two inquiry-based learning activities that use real geophysical data collected by scientists studying the buried Chicxulub feature as a

Engineering evaluation of the General Motors (GM) diesel rating and capabilities

Energy Technology Data Exchange (ETDEWEB)

Gross, R.E.

1992-04-01

K-Reactor's number one GM diesel (GM-lK) suffered recurrent, premature piston pin bushing failures between July 1990 and January 1991. These failures raised a concern that the engine's original design capabilities were being exceeded. Were we asking old engines to do too much by powering 1200 kw (continuous) rated electrical generators Was excessive wear of the piston pin bushings a result of having exceeded the engine's capabilities (overload), or were the recent failures a direct result of poor quality, poor design, or defective replacement parts Considering the engine's overall performance for the past 30 years, during which an engine failure of this nature had never occurred, and the fact that 1200 kw was approximately 50% of the engine's original tested capability, Reactor Engineering did not consider it likely that an overloaded engine caused bushing failures. What seemed more plausible was that the engine's failure to perform was caused by deficiencies in, or poor quality of, replacement parts.The following report documents: (1) the results of K-Reactor EDG failure analysis; (2) correlation of P- and C-Reactor GM diesel teardowns; (3) the engine rebuild to blueprint specification; (4) how the engine was determined ready for test; (5) testing parameters that were developed; (6) a summary of test results and test insights; (7) how WSRC determined engine operation was acceptable; (8) independent review of 1200 kw operational data; (9) approval of the engines' 12OOkw continuous rating.

Study of the $B^{0}\\rightarrow\\chi_{c1,2} K^{*0}$ decays at the LHCb experiment

CERN Document Server

Polyakov, Ivan

In this research, the ratios of the branching fractions of the $B^{0}\\rightarrow\\chi_{c1} K^{*0}$, $B^{0}\\rightarrow\\chi_{c2} K^{*0}$ and $B^{0}\\rightarrow J/\\psi K^{*0}$ decays are measured: \\begin{equation*} \\begin{array}{lll} \\dfrac{{\\cal B}(B^{0}\\rightarrow \\chi_{c1} K^{*0})}{{\\cal B}(B^{0}\\rightarrow J/\\psi K^{*0})} &=& (19.8~\\pm1.1~(stat)\\pm1.2~(syst)\\pm0.9\\,({\\cal B}_{\\chi_{c1}}))\\times 10^{-2}, \

Respiration shutoff in Escherichia coli K12 strains is induced by far ultraviolet radiations and by mitomycin C

International Nuclear Information System (INIS)

Swenson, P.A.; Norton, I.L.

1984-01-01

Near ultraviolet radiations (UV) cause respiration to shutoff in Escherichia coli B/r. It has been reported that E. coli K12 strains do not shut off respiration after UV. It is also reported that mitomycin C did not cause this 'SOS' response. In this paper it is reported that higher UV fluences than were previously used will cause respiration shutoff in K12 strain W3110 and that cyclic AMP increases the sensitivity of respiration shutoff of irradiated cell suspensions. Also mitomycin C shuts off respiration in this strain. Neither UV nor mitomycin C causes respiration shutoff in the recA56 derivative of W3110. Thus respiration shutoff is a recA dependent response to UV and mitomycin C in E. coli K12 strains. (Auth.)

Blueprint for Incorporating Service Learning: A Basic, Developmental, K-12 Service Learning Typology

Science.gov (United States)

Terry, Alice W.; Bohnenberger, Jann E.

2004-01-01

Citing the need for a basic, K-12 developmental framework for service learning, this article describes such a model. This model, an inclusive typology of service learning, distinguishes three levels of service learning: Community Service, Community Exploration, and Community Action. The authors correlate this typology to Piaget's cognitive…

A Nonverbal Language for Imagining and Learning: Dance Education in K-12 Curriculum

Science.gov (United States)

Hanna, Judith Lynne

2008-01-01

Curriculum theorists have provided a knowledge base concerning aesthetics, agency, creativity, lived experience, transcendence, learning through the body, and the power of the arts to engender visions of alternative possibilities in culture, politics, and the environment. However, these theoretical threads do not reveal the potential of K-12 dance…

Technology Integration in K-12 Science Classrooms: An Analysis of Barriers and Implications

Science.gov (United States)

Hechter, Richard P.; Vermette, Laurie Anne

2013-01-01

This paper examines the barriers to technology integration for Manitoban K-12 inservice science educators (n = 430) based on a 10-item online survey; results are analyzed according to teaching stream using the Technology, Pedagogy, and Content Knowledge (TPACK) framework. Quantitative descriptive statistics indicated that the leading barriers…

Health Education Teacher Resource Handbook: A Practical Guide for K-12 Health Education.

Science.gov (United States)

Mahoney, Beverly Saxton, Ed.; Olsen, Larry K., Ed.

This handbook provides background information on the health curriculum, as well as current, comprehensive information on publications, standards, and special materials for K-12 health education. The manual begins with an introduction, by P. Bruce Uhrmacher, which provides an overview of the ideologies and philosophies that have affected curriculum…

AR-12 suppresses dengue virus replication by down-regulation of PI3K/AKT and GRP78.

Science.gov (United States)

Chen, Hsin-Hsin; Chen, Chien-Chin; Lin, Yee-Shin; Chang, Po-Chun; Lu, Zi-Yi; Lin, Chiou-Feng; Chen, Chia-Ling; Chang, Chih-Peng

2017-06-01

Dengue virus (DENV) infection has become a public health issue of worldwide concern and is a serious health problem in Taiwan, yet there are no approved effective antiviral drugs to treat DENV. The replication of DENV requires both viral and cellular factors. Targeting host factors may provide a potential antiviral strategy. It has been known that up-regulation of PI3K/AKT signaling and GRP78 by DENV infection supports its replication. AR-12, a celecoxib derivative with no inhibiting activity on cyclooxygenase, shows potent inhibitory activities on both PI3K/AKT signaling and GRP78 expression levels, and recently has been found to block the replication of several hemorrhagic fever viruses. However the efficacy of AR-12 in treating DENV infection is still unclear. Here, we provide evidence to show that AR-12 is able to suppress DENV replication before or after virus infection in cell culture and mice. The antiviral activities of AR-12 are positive against infection of the four different DENV serotypes. AR-12 significantly down-regulates the PI3K/AKT activity and GRP78 expression in DENV infected cells whereas AKT and GRP78 rescue are able to attenuate anti-DENV effect of AR-12. Using a DENV-infected suckling mice model, we further demonstrate that treatment of AR-12 before or after DENV infection reduces virus replication and mice mortality. In conclusion, we uncover the potential efficacy of AR-12 as a novel drug for treating dengue. Copyright © 2017 Elsevier B.V. All rights reserved.

Electrical and microstructural properties of CaTiO3-doped K1/2Na1 ...

Indian Academy of Sciences (India)

KNN) and CaTiO3- modified K1/2Na1/2NbO3 (CTO-KNN) systems, were investigated. Discs doped with 0 to 0.55% mol of CaTiO3 (CTO) were sintered at 1125°C for 2 h. Although minority phases were found in doped samples, CaTiO3 was not ...

Negotiating Science and Engineering: An Exploratory Case Study of a Reform-Minded Science Teacher

Science.gov (United States)

Guzey, S. Selcen; Ring-Whalen, Elizabeth A.

2018-01-01

Engineering has been slowly integrated into K-12 science classrooms in the United States as the result of recent science education reforms. Such changes in science teaching require that a science teacher is confident with and committed to content, practices, language, and cultures related to both science and engineering. However, from the…

Involvement of IGF-1 and MEOX2 in PI3K/Akt1/2 and ERK1/2 pathways mediated proliferation and differentiation of perivascular adipocytes.

Science.gov (United States)

Liu, Ping; Kong, Feng; Wang, Jue; Lu, Qinghua; Xu, Haijia; Qi, Tonggang; Meng, Juan

2015-02-01

Perivascular adipocyte (PVAC) proliferation and differentiation were closely involved in cardiovascular disease. We aimed to investigate whether phosphatidylinositol 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) signaling pathways enhance PVAC functions activated by insulin-like growth factor 1(IGF-1) and suppressed by mesenchyme homeobox 2 (MEOX2). In this study, PVACs from primary culture were cultured and induced to differentiate. Cell viability assays demonstrated that IGF-1 promoted PVAC proliferation and differentiation. However MEOX2 counteracted these IGF-1-mediated actions. Flow Cytometry revealed that IGF-1 increased S phase cells and decreased apoptosis; however, MEOX2 decreased S phase cells, increased G0-G1 phase cells, and promoted apoptosis. During PVAC proliferation and differentiation, IGF-1 activated PI3K/Akt1/2 and ERK1/2 signaling pathways, upregulated the expression of these signaling proteins and FAS, and increased PVAC lipid content. In contrast, MEOX2 constrained the phosphorylation of ERK1/2 and Akt1/2 protein, down-regulated these signaling molecules and FAS, and decreased PVAC lipid content. Instead, MEOX2 knockdown enhanced the ERK1/2 and Akt1/2 phosphorylation, augmented the expression of these signaling molecules and FAS, and increased PVAC lipid content. Our findings suggested that PI3K/Akt1/2 and ERK1/2 activation mediated by IGF-1 is essential for PVAC proliferation and differentiation, and MEOX2 is a promising therapeutic gene to intervene in the signaling pathways and inhibit PVAC functions. Copyright © 2014 Elsevier Inc. All rights reserved.

Tobacco Use Prevention Education. K-12 Lesson Plans from the Montana Model Curriculum for Health Enhancement.

Science.gov (United States)

Montana State Office of Public Instruction, Helena.

This publication presents K-12 tobacco use prevention lesson plans for schools in the state of Montana. Lessons for students in grades K-6 include: family connections; body tracing; smokeless tobacco; prenatal development; tobacco look-alikes; tobacco chemicals; analyzing tobacco and alcohol ads; tobacco use and the lungs; and a personal health…

Keeping Pace with K-12 Online & Blended Learning: An Annual Review of Policy and Practice. 10 Year Anniversary Issue

Science.gov (United States)

Watson, John; Murin, Amy; Vashaw, Lauren; Gemin, Butch; Rapp, Chris

2013-01-01

"Keeping Pace with K-12 Online & Blended Learning" (2013), the 10th in a series of annual reports that began in 2004, examines the status of K-12 online education across the country. The report provides an overview of the latest policies, practices, and trends affecting online learning programs across all 50 states. In this 10th…

Addressing the Nets for Students through Constructivist Technology Use in K-12 Classrooms

Science.gov (United States)

Niederhauser, Dale S.; Lindstrom, Denise L.

2006-01-01

The National Educational Technology Standards for Students promote constructivist technology use for K-12 students in U.S. schools. In this study, researchers reported on 716 cases in which teachers described technology-based activities they conducted with their students. Narrative analysis was used to examine case transcripts relative to the…

Is K-12 Blended Learning Disruptive? An Introduction to the Theory of Hybrids

Science.gov (United States)

Christensen, Clayton M.; Horn, Michael B.; Staker, Heather

2013-01-01

The Clayton Christensen Institute for Disruptive Innovation, formerly the Innosight Institute, has published three papers describing the rise of K-12 blended learning--that is, formal education programs that combine online learning and brick-and-mortar schools. This fourth paper is the first to analyze blended learning through the lens of…

Cisco Networking Academy: Next-Generation Assessments and Their Implications for K-12 Education

Science.gov (United States)

Liu, Meredith

2014-01-01

To illuminate the possibilities for next-generation assessments in K-12 schools, this case study profiles the Cisco Networking Academy, which creates comprehensive online training curriculum to teach networking skills. Since 1997, the Cisco Networking Academy has served more than five million high school and college students and now delivers…

Investigation of the structural requirements of K-Ras(G12D) selective inhibitory peptide KRpep-2d using alanine scans and cysteine bridging.

Science.gov (United States)

Niida, Ayumu; Sasaki, Shigekazu; Yonemori, Kazuko; Sameshima, Tomoya; Yaguchi, Masahiro; Asami, Taiji; Sakamoto, Kotaro; Kamaura, Masahiro

2017-06-15

A structure-activity relationship study of a K-Ras(G12D) selective inhibitory cyclic peptide, KRpep-2d was performed. Alanine scanning of KRpep-2d focusing on the cyclic moiety showed that Leu 7 , Ile 9 , and Asp 12 are the key elements for K-Ras(G12D) selective inhibition of KRpep-2d. The cysteine bridging was also examined to identify the stable analog of KRpep-2d under reductive conditions. As a result, the KRpep-2d analog (12) including mono-methylene bridging showed potent K-Ras(G12D) selective inhibition in both the presence and the absence of dithiothreitol. This means that mono-methylene bridging is an effective strategy to obtain a reduction-resistance analog of parent disulfide cyclic peptides. Peptide 12 inhibited proliferation of K-Ras(G12D)-driven cancer cells significantly. These results gave valuable information for further optimization of KRpep-2d to provide novel anti-cancer drug candidates targeting the K-Ras(G12D) mutant. Copyright © 2017 Elsevier Ltd. All rights reserved.

A high efficiency 10 kWe microcogenerator based on an Atkinson cycle internal combustion engine

International Nuclear Information System (INIS)

Capaldi, Pietro

2014-01-01

The paper focuses on the design and the overall performance of a 10 kW electric power microcogeneration plant suitable for local energy production, based on an Atkinson-cycle internal combustion engine prototype and entirely set by Istituto Motori of the Italian National Research Council. The engine was originally a wide-spread Diesel automotive unit, then converted into a methane spark ignition system and finally modified to perform an Atkinson/Miller cycle with an extended expansion, capable of a higher global efficiency and low gaseous emissions. The paper starts by defining the ratio which leaded to this specific choice among many other automotive and industrial engines, in order to obtain a reliable, long endurance, cost effective, high efficiency base, suitable for microcogeneration in residential or commercial applications. The new engine has been coupled with a liquid cooled induction generator, a set of heat exchangers and finally placed in a sealed containing case, to reduce both noise emission and heat losses. Then the plant has been tested as an electricity and heat production system, ready for grid connection thanks to a new designed management/control system. During endurance test a complete description of its functioning behaviour has been given. - Highlights: • A new high efficiency microcogenerator based on an Atkinson/Miller cycle engine. • Atkinson cycle together with stoichiometric operation deliver better performance. • A cost-effective microcogenerator based on widespread elements (automotive engine). • The chosen automotive engine has heavy duty characteristics (Diesel derived). • A conversion criteria from a Diesel to an Atkinson cycle engine was individuated

Engineering of beam direct conversion for a 120-kV, 1-MW ion beam

International Nuclear Information System (INIS)

Barr, W.L.; Doggett, J.N.; Hamilton, G.W.; Kinney, J.D.; Moir, R.W.

1977-01-01

Practical systems for beam direct conversion are required to recover the energy from ion beams at high efficiency and at very high beam power densities in the environment of a high-power, neutral-injection system. Such an experiment is now in progress using a 120-kV beam with a maximum total current of 20 A. After neutralization, the H + component to be recovered will have a power of approximately 1MW. A system testing these concepts has been designed and tested at 15 kV, 2 kW in preparation for the full-power tests. The engineering problems involved in the full-power tests affect electron suppression, gas pumping, voltage holding, diagnostics, and measurement conditions. Planning for future experiments at higher power includes the use of cryopumping and electron suppression by a magnetic field rather than by an electrostatic field. Beam direct conversion for large fusion experiments and reactors will save millions of dollars in the cost of power supplies and electricity and will dispose of the charged beam under conditions that may mot be possible by other techniques

Engineering of beam direct conversion for a 120-kV, 1-MW ion beam

International Nuclear Information System (INIS)

Barr, W.L.; Doggett, J.N.; Hamilton, G.W.; Kinney, J.D.; Moir, R.W.

1977-01-01

Practical systems for beam direct conversion are required to recover the energy from ion beams at high efficiency and at very high beam power densities in the environment of a high-power, neutral-injection system. Such an experiment is now in progress using a 120-kV beam with a maximum total current of 20 A. After neutralization, the H + component to be recovered will have a power of approximately 1 MW. A system testing these concepts has been designed and tested at 15 kV, 2 kW in preparation for the full-power tests. The engineering problems involved in the full-power tests affect electron suppression, gas pumping, voltage holding, diagnostics, and measurement conditions. Planning for future experiments at higher power includes the use of cryopumping and electron suppression by a magnetic field rather than by an electrostatic field. Beam direct conversion for large fusion experiments and reactors will save millions of dollars in the cost of power supplies and electricity and will dispose of the charged beam under conditions that may not be possible by other techniques

Restriction alleviation of phage λ in Escherichia Coli K-12 cells after γ-irradiation

International Nuclear Information System (INIS)

Rabinkova, E.V.; Torosyan, M.V.; Fradkin, G.E.

1987-01-01

In γ-irradiated cells of Escherichia coli K-12 restriction allevation of an unmodified phage λ is only observed in AB1157 strain. No restriction allevation by γ-rays is registered in AB1157 mutants (rec A and ssb-1)

Effect of Streptococcus salivarius K12 on the in vitro growth of Candida albicans and its protective effect in an oral candidiasis model.

Science.gov (United States)

Ishijima, Sanae A; Hayama, Kazumi; Burton, Jeremy P; Reid, Gregor; Okada, Masashi; Matsushita, Yuji; Abe, Shigeru

2012-04-01

Oral candidiasis is often accompanied by severe inflammation, resulting in a decline in the quality of life of immunosuppressed individuals and elderly people. To develop a new oral therapeutic option for candidiasis, a nonpathogenic commensal oral probiotic microorganism, Streptococcus salivarius K12, was evaluated for its ability to modulate Candida albicans growth in vitro, and its therapeutic activity in an experimental oral candidiasis model was tested. In vitro inhibition of mycelial growth of C. albicans was determined by plate assay and fluorescence microscopy. Addition of S. salivarius K12 to modified RPMI 1640 culture medium inhibited the adherence of C. albicans to the plastic petri dish in a dose-dependent manner. Preculture of S. salivarius K12 potentiated its inhibitory activity for adherence of C. albicans. Interestingly, S. salivarius K12 was not directly fungicidal but appeared to inhibit Candida adhesion to the substratum by preferentially binding to hyphae rather than yeast. To determine the potentially anti-infective attributes of S. salivarius K12 in oral candidiasis, the probiotic was administered to mice with orally induced candidiasis. Oral treatment with S. salivarius K12 significantly protected the mice from severe candidiasis. These findings suggest that S. salivarius K12 may inhibit the process of invasion of C. albicans into mucous surfaces or its adhesion to denture acrylic resins by mechanisms not associated with the antimicrobial activity of the bacteriocin. S. salivarius K12 may be useful as a probiotic as a protective tool for oral care, especially with regard to candidiasis.

How to Launch an Energy Star Energy Efficiency Competition for K-12 Schools

Science.gov (United States)

Utebay Kudret; McArthur, Ashley

2012-01-01

In recent years, schools have been forced by rising costs and shrinking budgets to stretch their resources further than ever before in order to meet the educational needs of today's students. EPA's ENERGY STAR program helps K-12 schools and districts improve energy efficiency, reduce operating costs and redirect critical resources into the…

Mobile Apps for Reflection in Learning: A Design Research in K-12 Education

Science.gov (United States)

Leinonen, Teemu; Keune, Anna; Veermans, Marjaana; Toikkanen, Tarmo

2016-01-01

This study takes a design-based research approach to explore how applications designed for mobile devices could support reflection in learning in K-12 education. Use of mobile devices is increasing in schools. Most of the educational apps support single-person use of interactive learning materials, simulations and learning games. Apps designed to…

Teaching and Learning with Mobile Computing Devices: Case Study in K-12 Classrooms

Science.gov (United States)

Grant, Michael M.; Tamim, Suha; Brown, Dorian B.; Sweeney, Joseph P.; Ferguson, Fatima K.; Jones, Lakavious B.

2015-01-01

While ownership of mobile computing devices, such as cellphones, smartphones, and tablet computers, has been rapid, the adoption of these devices in K-12 classrooms has been measured. Some schools and individual teachers have integrated mobile devices to support teaching and learning. The purpose of this qualitative research was to describe the…

State Capacity to Link K-12/Postsecondary Data Systems and Report Key Indicators

Science.gov (United States)

Data Quality Campaign, 2016

2016-01-01

The Every Student Succeeds Act (ESSA) provides an opportunity to produce high quality postsecondary indicators and, as available, publicly report them in ways that inform, engage, and empower communities. As first "required" in 2009's American Recovery and Reinvestment Act (ARRA) stimulus law, almost every state has linked its K-12 and…

Science and Engineering of the Environment of Los Angeles: A GK-12 Experiment at Developing Science Communications Skills in UCLA's Graduate Program

Science.gov (United States)

Moldwin, M. B.; Hogue, T. S.; Nonacs, P.; Shope, R. E.; Daniel, J.

2008-12-01

Many science and research skills are taught by osmosis in graduate programs with the expectation that students will develop good communication skills (speaking, writing, and networking) by observing others, attending meetings, and self reflection. A new National Science Foundation Graduate Teaching Fellows in K- 12 Education (GK-12; http://ehrweb.aaas.org/gk12new/) program at UCLA (SEE-LA; http://measure.igpp.ucla.edu/GK12-SEE-LA/overview.html ) attempts to make the development of good communication skills an explicit part of the graduate program of science and engineering students. SEE-LA places the graduate fellows in two pairs of middle and high schools within Los Angeles to act as scientists-in- residence. They are partnered with two master science teachers and spend two-days per week in the classroom. They are not student teachers, or teacher aides, but scientists who contribute their content expertise, excitement and experience with research, and new ideas for classroom activities and lessons that incorporate inquiry science. During the one-year fellowship, the graduate students also attend a year-long Preparing Future Faculty seminar that discusses many skills needed as they begin their academic or research careers. Students are also required to include a brief (two-page) summary of their research that their middle or high school students would be able to understand as part of their published thesis. Having students actively thinking about and communicating their science to a pre-college audience provides important science communication training and helps contribute to science education. University and local pre- college school partnerships provide an excellent opportunity to support the development of graduate student communication skills while also contributing significantly to the dissemination of sound science to K-12 teachers and students.

Radiation inactivation of Salmonella panama and Escherichia coli K 12 present on deep-frozen broiler carcasses

International Nuclear Information System (INIS)

Mulder, R.W.A.W.

1976-01-01

Low doses of ionizing radiation have been used to extend the shelf life of refrigerated poultry carcasses and to reduce the numbers of Salmonellae present. This report gives results of experiments on irradiation of deep-frozen poultry carcasses which were, before freezing, artificially contaminated with Salmonella panama and with a nalidixic acid-resistant Escherichia coli K 12. The D-values (decimal reduction) obtained with the inoculated carcasses were compared with D-values obtained with carcasses which were slaughtered in the normal way. The D-values for S.panama and for E.coli K 12 were 64.9 krad and 55.9 krad in the dripwater. Under commercial conditions approximately 100 krad were required for one decimal reduction of the Enterobacteriaceae present. The D-values estimated on the skin were higher for S.panama than for E.coli K 12 (128.6 krad vs 57.6 krad). If it is assumed that 1 positive carcass in 10,000 is allowed, the deep-frozen carcasses should be irradiated with doses of at least 700 krad to be sure of the absence of the tested S.panama strain. (orig.) [de

Radiation inactivation of Salmonella panama and Escherichia coli K 12 present on deep-frozen broiler carcasses

Energy Technology Data Exchange (ETDEWEB)

Mulder, R W.A.W. [Spelderholt Inst. for Poultry Research, Beekbergen (Netherlands). Processing Dept.

1976-01-01

Low doses of ionizing radiation have been used to extend the shelf life of refrigerated poultry carcasses and to reduce the numbers of Salmonellae present. This report gives results of experiments on irradiation of deep-frozen poultry carcasses which were, before freezing, artificially contaminated with Salmonella panama and with a nalidixic acid-resistant Escherichia coli K 12. The D-values (decimal reduction) obtained with the inoculated carcasses were compared with D-values obtained with carcasses which were slaughtered in the normal way. The D-values for S.panama and for E.coli K 12 were 64.9 krad and 55.9 krad in the dripwater. Under commercial conditions approximately 100 krad were required for one decimal reduction of the Enterobacteriaceae present. The D-values estimated on the skin were higher for S.panama than for E.coli K 12 (128.6 krad vs 57.6 krad). If it is assumed that 1 positive carcass in 10,000 is allowed, the deep-frozen carcasses should be irradiated with doses of at least 700 krad to be sure of the absence of the tested S.panama strain.

Fluency and Accuracy in Alphabet Writing by Keyboarding : A Cross-Sectional Study in Spanish-Speaking Children With and Without Learning Disabilities

NARCIS (Netherlands)

Bisschop, Elaine; Morales, Celia; Gil, Verónica; Jiménez-Suárez, Elizabeth

2017-01-01

The aim of this study was to analyze whether children with and without difficulties in handwriting, spelling, or both differed in alphabet writing when using a keyboard. The total sample consisted of 1,333 children from Grades 1 through 3. Scores on the spelling and handwriting factors from the

Impact of Guided Notes on Achievement in K-12 and Special Education Students

Science.gov (United States)

Larwin, Karen H.; Dawson, Daniel; Erickson, Matthew; Larwin, David A.

2012-01-01

The common practice of using of guided notes in the K-12 and special education classroom is not fully appreciated or understood. In an effort to add to the existing research about this phenomenon, the current investigation expands on previously published research and one previously published meta-analysis that examined the impact of guided notes…

Preparing for Online Teaching: Web-Based Assessment and Communication Skills in K12

Science.gov (United States)

DeNisco, Alison

2013-01-01

Students are doing less hand-raising and more clicking as online classes become increasingly popular in K12 instruction, both in combination with brick-and-mortar classrooms and in independent full-time virtual schools. With online instruction comes a change in the nature of teaching, communicating with, and assessing students. As schools move to…

Perceptions of Educational Barriers Affecting the Academic Achievement of Latino K-12 Students

Science.gov (United States)

Becerra, David

2012-01-01

This study examined different factors affecting the perceptions of barriers in academic achievement of Latino K-12 students. The study used data from 1,508 participants who identified themselves as being of Hispanic or Latino heritage in the 2004 National Survey of Latinos: Education, compiled by the Pew Hispanic Center between August 7 and…

(Re)Defining the Filipino: Notions of Citizenship in the New K+12 Curriculum

Science.gov (United States)

de los Reyes, Elizer Jay

2013-01-01

In June 2012, the Philippine government implemented what it called the K+12 Curriculum which reformed its basic education system by adding two more years of schooling to the then existing 10-year structure. Complicated by the long experience and participation of the Filipinos in the diaspora, the constantly lingering thought of leaving for greener…

Pumped helium system for cooling positron and electron traps to 1.2 K

CERN Document Server

Wrubel, J; Kolthammer, W S; Larochelle, P; McConnell, R; Richerme, P; Grzonka, D; Oelert, W; Sefzick, T; Zielinski, M; Borbely, J S; George, M C; Hessels, E A; Storry, C H; Weel, M; Mullers, A; Walz, J; Speck, A

2011-01-01

Extremely precise tests of fundamental particle symmetries should be possible via laser spectroscopy of trapped antihydrogen ((H) over bar) atoms. (H) over bar atoms that can be trapped must have an energy in temperature units that is below 0.5 K-the energy depth of the deepest magnetic traps that can currently be constructed with high currents and superconducting technology. The number of atoms in a Boltzmann distribution with energies lower than this trap depth depends sharply upon the temperature of the thermal distribution. For example, ten times more atoms with energies low enough to be trapped are in a thermal distribution at a temperature of 1.2 K than for a temperature of 4.2 K. To date, (H) over bar atoms have only been produced within traps whose electrode temperature is 4.2 K or higher. A lower temperature apparatus is desirable if usable numbers of atoms that can be trapped are to eventually be produced. This report is about the pumped helium apparatus that cooled the trap electrodes of an (H) ove...

Decoding English Alphabet Letters Using EEG Phase Information

Directory of Open Access Journals (Sweden)

YiYan Wang

2018-02-01

Full Text Available Increasing evidence indicates that the phase pattern and power of the low frequency oscillations of brain electroencephalograms (EEG contain significant information during the human cognition of sensory signals such as auditory and visual stimuli. Here, we investigate whether and how the letters of the alphabet can be directly decoded from EEG phase and power data. In addition, we investigate how different band oscillations contribute to the classification and determine the critical time periods. An English letter recognition task was assigned, and statistical analyses were conducted to decode the EEG signal corresponding to each letter visualized on a computer screen. We applied support vector machine (SVM with gradient descent method to learn the potential features for classification. It was observed that the EEG phase signals have a higher decoding accuracy than the oscillation power information. Low-frequency theta and alpha oscillations have phase information with higher accuracy than do other bands. The decoding performance was best when the analysis period began from 180 to 380 ms after stimulus presentation, especially in the lateral occipital and posterior temporal scalp regions (PO7 and PO8. These results may provide a new approach for brain-computer interface techniques (BCI and may deepen our understanding of EEG oscillations in cognition.

Driven by Beliefs: Understanding Challenges Physical Science Teachers Face When Integrating Engineering and Physics

Science.gov (United States)

Dare, Emily A.; Ellis, Joshua A.; Roehrig, Gillian H.

2014-01-01

It is difficult to ignore the increased use of technological innovations in today's world, which has led to various calls for the integration of engineering into K-12 science standards. The need to understand how engineering is currently being brought to science classrooms is apparent and necessary in order to address these calls for integration.…

Environmental and genetic factors affecting mutability to aminoglycoside antibiotics among Escherichia coli K12 strains

Directory of Open Access Journals (Sweden)

Monteiro A.C.M.

2003-01-01

Full Text Available Environmental and genetic factors affecting the in vitro spontaneous mutation frequencies to aminoglycoside resistance in Escherichia coli K12 were investigated. Spontaneous mutation frequencies to kanamycin resistance were at least 100 fold higher on modified Luria agar (L2 plates, when compared to results obtained in experiments carried out with Nutrient agar (NA plates. In contrast to rifampincin, the increased mutability to kanamycin resistance could not be attributed to a mutator phenotype expressed by DNA repair defective strains. Kanamycin mutant selection windows and mutant preventive concentrations on L2 plates were at least fourfold higher than on NA plates, further demonstrating the role of growth medium composition on the mutability to aminoglycosides. Mutability to kanamycin resistance was increased following addition of sorbitol, suggesting that osmolarity is involved on the spontaneous mutability of E. coli K12 strains to aminoglycosides. The spontaneous mutation rates to kanamycin resistance on both L2 and NA plates were strictly associated with the selective antibiotic concentrations. Moreover, mutants selected at different antibiotic concentrations expressed heterogeneous resistance levels to kanamycin and most of them expressing multiple resistance to all tested aminoglycoside antibiotics (gentamicin, neomycin, amykacin and tobramycin. These results will contribute to a better understanding of the complex nature of aminoglycoside resistance and the emergence of spontaneous resistant mutants among E. coli K12 strains.

Lunar and Planetary Science XXXV: Engaging K-12 Educators, Students, and the General Public in Space Science Exploration

Science.gov (United States)

2004-01-01

The session "Engaging K-12 Educators, Students, and the General Public in Space Science Exploration" included the following reports:Training Informal Educators Provides Leverage for Space Science Education and Public Outreach; Teacher Leaders in Research Based Science Education: K-12 Teacher Retention, Renewal, and Involvement in Professional Science; Telling the Tale of Two Deserts: Teacher Training and Utilization of a New Standards-based, Bilingual E/PO Product; Lindstrom M. M. Tobola K. W. Stocco K. Henry M. Allen J. S. McReynolds J. Porter T. T. Veile J. Space Rocks Tell Their Secrets: Space Science Applications of Physics and Chemistry for High School and College Classes -- Update; Utilizing Mars Data in Education: Delivering Standards-based Content by Exposing Educators and Students to Authentic Scientific Opportunities and Curriculum; K. E. Little Elementary School and the Young Astronaut Robotics Program; Integrated Solar System Exploration Education and Public Outreach: Theme, Products and Activities; and Online Access to the NEAR Image Collection: A Resource for Educators and Scientists.

Title list of selected Soviet reports in the fields of nuclear research and nuclear engineering. 12

International Nuclear Information System (INIS)

Schumann, G.; Sube, R.

1979-12-01

136 titles of reports issued by Soviet institutes (KFTI, EFI, IAE, IFVE, ITEF, NIIAR, NIIEFA, FEI, RI, SFTI) in the fields of nuclear research and nuclear engineering have been arranged according to the INIS subject scope. The reports are available on a loan basis from ZfK Rossendorf, Information Department, Dresden

Recognizing protein–protein interfaces with empirical potentials and reduced amino acid alphabets

Directory of Open Access Journals (Sweden)

Wodak Shoshana

2007-07-01

Full Text Available Abstract Background In structural genomics, an important goal is the detection and classification of protein–protein interactions, given the structures of the interacting partners. We have developed empirical energy functions to identify native structures of protein–protein complexes among sets of decoy structures. To understand the role of amino acid diversity, we parameterized a series of functions, using a hierarchy of amino acid alphabets of increasing complexity, with 2, 3, 4, 6, and 20 amino acid groups. Compared to previous work, we used the simplest possible functional form, with residue–residue interactions and a stepwise distance-dependence. We used increased computational ressources, however, constructing 290,000 decoys for 219 protein–protein complexes, with a realistic docking protocol where the protein partners are flexible and interact through a molecular mechanics energy function. The energy parameters were optimized to correctly assign as many native complexes as possible. To resolve the multiple minimum problem in parameter space, over 64000 starting parameter guesses were tried for each energy function. The optimized functions were tested by cross validation on subsets of our native and decoy structures, by blind tests on series of native and decoy structures available on the Web, and on models for 13 complexes submitted to the CAPRI structure prediction experiment. Results Performance is similar to several other statistical potentials of the same complexity. For example, the CAPRI target structure is correctly ranked ahead of 90% of its decoys in 6 cases out of 13. The hierarchy of amino acid alphabets leads to a coherent hierarchy of energy functions, with qualitatively similar parameters for similar amino acid types at all levels. Most remarkably, the performance with six amino acid classes is equivalent to that of the most detailed, 20-class energy function. Conclusion This suggests that six carefully chosen amino

A systems biology approach identified different regulatory networks targeted by KSHV miR-K12-11 in B cells and endothelial cells.

Science.gov (United States)

Yang, Yajie; Boss, Isaac W; McIntyre, Lauren M; Renne, Rolf

2014-08-08

Kaposi's sarcoma associated herpes virus (KSHV) is associated with tumors of endothelial and lymphoid origin. During latent infection, KSHV expresses miR-K12-11, an ortholog of the human tumor gene hsa-miR-155. Both gene products are microRNAs (miRNAs), which are important post-transcriptional regulators that contribute to tissue specific gene expression. Advances in target identification technologies and molecular interaction databases have allowed a systems biology approach to unravel the gene regulatory networks (GRNs) triggered by miR-K12-11 in endothelial and lymphoid cells. Understanding the tissue specific function of miR-K12-11 will help to elucidate underlying mechanisms of KSHV pathogenesis. Ectopic expression of miR-K12-11 differentially affected gene expression in BJAB cells of lymphoid origin and TIVE cells of endothelial origin. Direct miRNA targeting accounted for a small fraction of the observed transcriptome changes: only 29 genes were identified as putative direct targets of miR-K12-11 in both cell types. However, a number of commonly affected biological pathways, such as carbohydrate metabolism and interferon response related signaling, were revealed by gene ontology analysis. Integration of transcriptome profiling, bioinformatic algorithms, and databases of protein-protein interactome from the ENCODE project identified different nodes of GRNs utilized by miR-K12-11 in a tissue-specific fashion. These effector genes, including cancer associated transcription factors and signaling proteins, amplified the regulatory potential of a single miRNA, from a small set of putative direct targets to a larger set of genes. This is the first comparative analysis of miRNA-K12-11's effects in endothelial and B cells, from tissues infected with KSHV in vivo. MiR-K12-11 was able to broadly modulate gene expression in both cell types. Using a systems biology approach, we inferred that miR-K12-11 establishes its GRN by both repressing master TFs and influencing

Ecological optimization of quantum spin-1/2 heat engine at the classical limit

International Nuclear Information System (INIS)

Chen, T-H

2006-01-01

The purpose of this paper is to present a study of finite-time thermodynamics applied to evaluate the ecological performance of a quantum heat engine which operates between two thermal reservoirs using the working substance of spin-1/2 systems. The quantum heat engine cycle is composed of two isothermal processes, an adiabatic process and an isomagnetic field process. A sequence of time evolution was determined from the quantum angular momentum rate based on the semigroup approach and the quantum master equation. The individual time duration is added to account for the total cycle time. The objective ecological function representing a compromise between power output and irreversibility is maximized with respect to cycle temperature ratio. Effects of thermal reservoir temperature ratio and magnetic field ratio on the ecological function have been discussed. A comparison of quantum heat engine performance under maximum ecological function and maximum power conditions is also presented

Effect of simulated microgravity on E. coli K12 MG1655 growth and gene expression

Data.gov (United States)

National Aeronautics and Space Administration — This study demonstrates simulated microgravity effects on E. coli K 12 MG1655 when grown on LB medium supplemented with glycerol. The results imply that E. coli...

African Journals Online: Browse Alphabetically -- letter K

African Journals Online (AJOL)

KCA Journal of Business Management ... In addition, the journal publishes invited research reviews and reports of ... Kiswahili is an interdisciplinary international journal devoted to the study of Kiswahili language, linguistics and literature.

Backward K*/sup 0/ production in the reaction pi /sup -/p to Lambda /sup 0/K/sup +/ pi /sup -/ at 9 and 12 GeV/c

CERN Document Server

Ferrer, A; Bouquet, B; D'Almagne, B; De Rosny, G; Nguyen, H; Petroff, P; Richard, F; Rivet, P; Roudeau, P; Rougé, A; Six, J; Treille, D; Volte, A; Yoshida, H

1981-01-01

The authors have analysed about 85000 fast Lambda /sup 0/ events, obtained in a fast proton triggered experiment performed at the CERN- Omega spectrometer at 9 and 12 GeV/c incident pi /sup -/ beam. Nearly 2500 Lambda /sup 0/K/sup +/ pi /sup -/ events have been isolated. They find strong production of quasi-two-body processes Lambda /sup 0/K* /sup 0/ and Sigma */sup -/K/sup +/ consistent with u-channel hyperon exchange. Results on Lambda /sup 0/ polarization, K*/sup 0/ decay parameters and differential cross sections are given for Lambda /sup 0 /K*/sup 0/(892) and Lambda /sup 0/K*/sup 0/(1430) final states. A comparison is made with the associated backward Lambda /sup 0/(1520)K* /sup 0/ production seen in the four-prong reaction pi /sup -/p to pK /sup -/K/sup +/ pi /sup -/ obtained in the same experiment. (13 refs).

Y2K of the society of chemical engineers, Japan; Kagaku kogakukai no 2000nen mondai

Energy Technology Data Exchange (ETDEWEB)

Kataoka, K. [Kobe University, Kobe (Japan)

2000-01-05

In this paper, the coming problem of the Y2K problems by the cataclysm of economic society that the Society of Chemical Engineers holds is described. And it is explained in dividing into the present problems for the development of the Society of Chemical Engineers, a science and technology promotion policy, a university/industry cooperation, a regional cooperation, an internationality and international contribution, an effect of an independent administrative corporation of national universities, the movement of a future plan, the terms of member needs and a base establishment. In the paragraph of the movement of a future plan, the facts that a basic philosophy of the Society of Chemical Engineers was suggested standing on the report of the Vision Settlement Preparation Committee organized in 1998, the Chemical Industry Vision 2011 Settlement Committee was inaugurated for constituting its future images and the Working Group composed of the members of the Industry Institute in their forties leading the next generation was established is introduced. (NEDO)

Dictionary of nuclear engineering. English-German-French-Russian. Kerntechnik. Englisch-Deutsch-Franzoesisch-Russisch

Energy Technology Data Exchange (ETDEWEB)

Sube, R

1985-01-01

This volume contains nearly 30,000 entries from all branches of nuclear engineering excluding biological aspects, health physics, and isotope applications in medicine and agriculture. The terminology used in the International Nuclear Information System (INIS) of the IAEA has been completely taken into account. Each English entry is numbered and is followed by corresponding terms in the other languages. Alphabetical indexes of the German, French, and Russian terms are included. At the end of the volume, there is a section devoted to the transliteration of place-names between the English names and their Cyrillic equivalents, and vice versa.

Leading by Following: An Analysis of How K-12 School Leaders Use Twitter

Science.gov (United States)

Sauers, Nicholas J.; Richardson, Jayson W.

2015-01-01

This study analyzed how active Twitter users who are also school leaders used the tool. The researchers collaboratively identified K-12 school leaders who were active on Twitter and then collected tweets from those school leaders. The final sample for this study included 115 Twitter users and over 180,000 tweets from those individuals. The results…

The anti-tumor efficacy of 3C23K, a glyco-engineered humanized anti-MISRII antibody, in an ovarian cancer model is mainly mediated by engagement of immune effector cells.

Science.gov (United States)

Estupina, Pauline; Fontayne, Alexandre; Barret, Jean-Marc; Kersual, Nathalie; Dubreuil, Olivier; Le Blay, Marion; Pichard, Alexandre; Jarlier, Marta; Pugnière, Martine; Chauvin, Maëva; Chardès, Thierry; Pouget, Jean-Pierre; Deshayes, Emmanuel; Rossignol, Alexis; Abache, Toufik; de Romeuf, Christophe; Terrier, Aurélie; Verhaeghe, Lucie; Gaucher, Christine; Prost, Jean-François; Pèlegrin, André; Navarro-Teulon, Isabelle

2017-06-06

Ovarian cancer is the leading cause of death in women with gynecological cancers and despite recent advances, new and more efficient therapies are crucially needed. Müllerian Inhibiting Substance type II Receptor (MISRII, also named AMHRII) is expressed in most ovarian cancer subtypes and is a novel potential target for ovarian cancer immunotherapy. We previously developed and tested 12G4, the first murine monoclonal antibody (MAb) against human MISRII. Here, we report the humanization, affinity maturation and glyco-engineering steps of 12G4 to generate the Fc-optimized 3C23K MAb, and the evaluation of its in vivo anti-tumor activity. The epitopes of 3C23K and 12G4 were strictly identical and 3C23K affinity for MISRII was enhanced by a factor of about 14 (KD = 5.5 × 10-11 M vs 7.9 × 10-10 M), while the use of the EMABling® platform allowed the production of a low-fucosylated 3C23K antibody with a 30-fold KD improvement of its affinity to FcγRIIIa. In COV434-MISRII tumor-bearing mice, 3C23K reduced tumor growth more efficiently than 12G4 and its combination with carboplatin was more efficient than each monotherapy with a mean tumor size of 500, 1100 and 100 mm3 at the end of treatment with 3C23K (10 mg/kg, Q3-4D12), carboplatin (60 mg/kg, Q7D4) and 3C23K+carboplatin, respectively. Conversely, 3C23K-FcKO, a 3C23K form without affinity for the FcγRIIIa receptor, did not display any anti-tumor effect in vivo. These results strongly suggested that 3C23K mechanisms of action are mainly Fc-related. In vitro, antibody-dependent cytotoxicity (ADCC) and antibody-dependent cell phagocytosis (ADCP) were induced by 3C23K, as demonstrated with human effector cells. Using human NK cells, 50% of the maximal lysis was obtained with a 46-fold lower concentration of low-fucosylated 3C23K (2.9 ng/ml) than of 3C23K expressed in CHO cells (133.35 ng/ml). As 3C23K induced strong ADCC with human PBMC but almost none with murine PBMC, antibody-dependent cell phagocytosis (ADCP) was

Giant strain with low cycling degradation in Ta-doped [Bi{sub 1/2}(Na{sub 0.8}K{sub 0.2}){sub 1/2}]TiO{sub 3} lead-free ceramics

Energy Technology Data Exchange (ETDEWEB)

Liu, Xiaoming; Tan, Xiaoli, E-mail: xtan@iastate.edu [Department of Materials Science and Engineering, Iowa State University, Ames, Iowa 50011 (United States)

2016-07-21

Non-textured polycrystalline [Bi{sub 1/2}(Na{sub 0.8}K{sub 0.2}){sub 1/2}](Ti{sub 1−x}Ta{sub x})O{sub 3} ceramics are fabricated and their microstructures and electrical properties are characterized. Transmission electron microscopy reveals the coexistence of the rhombohedral R3c and tetragonal P4bm phases in the form of nanometer-sized domains in [Bi{sub 1/2}(Na{sub 0.8}K{sub 0.2}){sub 1/2}]TiO{sub 3} with low Ta concentration. When the composition is x = 0.015, the electrostrain is found to be highly asymmetric under bipolar fields of ±50 kV/cm. A very large value of 0.62% is observed in this ceramic, corresponding to a large-signal piezoelectric coefficient d{sub 33}* of 1240 pm/V (1120 pm/V under unipolar loading). These values are greater than most previously reported lead-free polycrystalline ceramics and can even be compared with some lead-free piezoelectric single crystals. Additionally, this ceramic displays low cycling degradation; its electrostrain remains above 0.55% even after undergoing 10 000 cycles of ±50 kV/cm bipolar fields at 2 Hz. Therefore, Ta-doped [Bi{sub 1/2}(Na{sub 0.8}K{sub 0.2}){sub 1/2}]TiO{sub 3} ceramics show great potential for large displacement devices.

Trend of supersonic aircraft engine. Choonsokukiyo engine no doko

Energy Technology Data Exchange (ETDEWEB)

Yashima, S [Ishikawajima-Harima Heavy Industries, Co. Ltd., Tokyo (Japan)

1994-05-01

The present paper explained the R and D trend of supersonic aircraft engine in Europe, USA and Japan. Taking the high speed flight resistance into consideration, the engine must be characterized by its high exhaust gas speed and high specific thrust (ratio of thrust to the airflow rate) to secure strong thrust by a low airflow rate. Therefore, the turbojet is appropriate. However to reduce the fuel consumption during the cruising flight, the turbofan is normally used with a low by-pass ratio of 0.2 to 0.9. The thrust-to-weight ratio (thrust per unit weight) of low by-pass ratio turbofan engine equipped with afterburner is 7 to 8 in case of stronger thrust than 70kN. Its target value of development is 10. The specific thrust which is a performance parameter of engine exceeds 120s for the fighter engine and is about 30s for the passenger plane engine. The turbine inlet temperature is 2073K at the stage of element research. The overall pressure ratio ranges from 25 to 30. The reheating turbofan engine experimentally built for the research in Japan is 34kN in thrust and 7 in thrust-to-weight ratio. 8 refs., 9 figs.

17 CFR 201.550 - Summary suspensions pursuant to Exchange Act Section 12(k)(1)(A).

Science.gov (United States)

2010-04-01

... termination of suspension. Any person adversely affected by a suspension pursuant to Section 12(k)(1)(A) of... the public interest or for the protection of investors may file a sworn petition with the Secretary...

Operating Experiences with a Small-scale CHP Pilot Plant based on a 35 kWel Hermetic Four Cylinder Stirling Engine for Biomass Fuels

DEFF Research Database (Denmark)

Biedermann, F.; Carlsen, Henrik; Schoech, M.

2003-01-01

Within the scope of the RD&D project presented a small-scale CHP plant with a hermetic four cylinder Stirling engine for biomass fuels was developed and optimised in cooperation with the Technical University of Denmark, MAWERA Holzfeuerungsanlagen GesmbH, an Austrian biomass furnace and boiler...... exchanger of the Stirling engine, of the air preheater and of the entire combustion system. Furthermore, the optimisation of the pneumatic cleaning system to reduce ash deposition in the hot heat exchanger is of great relevance....... manufacturer, and BIOS BIOENERGIESYSTEME GmbH, an Austrian development and engineering company. Based on the technology developed, a pilot plant was designed and erected in Austria. The nominal electric power output of the plant is 35 kWel and the nominal thermal output amounts to approx. 220 kWth. The plant...

How should we teach diverse students? Cross-cultural comparison of diversity issues in K-12 schools in Japan and the US

Directory of Open Access Journals (Sweden)

Fuyu Shimomura

2016-02-01

Full Text Available Increasing student diversity in K-12 schools has gained attention in Japan and the US. In the US, racial diversity has historically shaped inequity in educational access and teacher quality. In Japan, regardless of its reputation for cultural homogeneity among its residents, issues surrounding student diversity have gained attention because of the increasing number of returnees—Japanese students raised overseas because of their parents’ expatriation. This paper compares and contrasts the diversity issues in K-12 school settings in both countries, and explores potential approaches to improve the accommodation of diversity in K-12 schools.

The interactions between IC engine thermodynamics and knock

International Nuclear Information System (INIS)

Caton, Jerald A.

2017-01-01

Highlights: • Importance of engine thermodynamics regarding knock was quantified. • Effects of compression ratio, engine speed and EGR on knock was reported. • Retarding combustion to avoid knock resulted in decreases of efficiency. - Abstract: The development of high efficiency spark-ignition internal combustion engines is often constrained by the occurrence of knock. Knock may result in engine damage, lower performance, and lower efficiency. The options for preventing knock often involve lower compression ratios, lower boost, retarded spark timing, and other design choices that are detrimental to engine performance and efficiency. Since knock is largely a function of the thermodynamic state of the unburned zone, the occurrence of knock is expected to be a strong function of the engine thermodynamics. The purpose of the current work is to couple a simple knock model with a comprehensive engine cycle simulation to determine the interactions between the engine thermodynamics and knock. This work has explored the effects of engine parameters such as compression ratio (4–12), engine speed (500–2500 rpm), inlet pressure (50–100 kPa), exhaust gas recirculation (0–25%), combustion duration and heat transfer on knock. In each case, the occurrence of knock is connected to the cylinder pressures and the gas temperatures of the unburned zone. For example for a compression ratio of 12, to avoid knock the brake thermal efficiency decreased from 36.5% to 34% due to retarding the combustion.

Benefits and Pitfalls: Simple Guidelines for the Use of Social Networking Tools in K-12 Education

Science.gov (United States)

Huffman, Stephanie

2013-01-01

The article will outline a framework for the use of social networking tools in K-12 education framed around four thought provoking questions: 1) what are the benefits and pitfalls of using social networking tools in P-12 education, 2) how do we plan effectively for the use of social networking tool, 3) what role does professional development play…

Mixed Methods Evaluation of Statewide Implementation of Mathematics Education Technology for K-12 Students

Science.gov (United States)

Brasiel, Sarah; Martin, Taylor; Jeong, Soojeong; Yuan, Min

2016-01-01

An extensive body of research has demonstrated that the use in a K-12 classroom of technology, such as the Internet, computers, and software programs, enhances the learning of mathematics (Cheung & Slavin, 2013; Cohen & Hollebrands, 2011). In particular, growing empirical evidence supports that certain types of technology, such as…