WorldWideScience

Sample records for jvf nj dx

  1. 33 CFR 80.501 - Tom's River, NJ to Cape May, NJ.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Tom's River, NJ to Cape May, NJ. 80.501 Section 80.501 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Fifth District § 80.501 Tom's River, NJ to Cape May, NJ...

  2. What Is the Relative Influence of NJ School Report Card Variables on NJ ASK 5 Scores?

    Science.gov (United States)

    Gemellaro, Dorian Marrone

    2012-01-01

    In this study, the researcher examined the strength and direction of relationships between NJ School Report Card Variables (NJ SRC) and 2008-2009 NJ ASK 5 Math and Language Arts Literacy (LAL) student test scores. Variables found to have an influence on standardized test scores in the extant literature were evaluated and reported. Analyses were…

  3. 33 CFR 80.170 - Sandy Hook, NJ to Tom's River, NJ.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Sandy Hook, NJ to Tom's River, NJ. 80.170 Section 80.170 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Atlantic Coast § 80.170 Sandy Hook, NJ to Tom's River...

  4. Boosting Wigner's nj-symbols

    CERN Document Server

    Speziale, Simone

    2016-01-01

    We study the SL(2,C) Clebsch-Gordan coefficients appearing in the lorentzian EPRL spin foam amplitudes for loop quantum gravity. We show how the amplitudes decompose into SU(2) nj-symbols at the vertices and integrals over boosts at the edges. The integrals define edge amplitudes that can be evaluated analytically using and adapting results in the literature, leading to a pure state sum model formulation. This procedure introduces virtual representations which, in a manner reminiscent to virtual momenta in Feynman amplitudes, are off-shell of the simplicity constraints present in the theory, but with the integrands that peak at the on-shell values. We point out some properties of the edge amplitudes which are helpful for numerical and analytical evaluations of spin foam amplitudes, and suggest among other things a simpler model useful for calculations of certain lowest order amplitudes. As an application, we estimate the large spin scaling behaviour of the simpler model, on a closed foam with all 4-valent edg...

  5. Boosting Wigner's nj-symbols

    Science.gov (United States)

    Speziale, Simone

    2017-03-01

    We study the SL (2 ,ℂ ) Clebsch-Gordan coefficients appearing in the Lorentzian EPRL spin foam amplitudes for loop quantum gravity. We show how the amplitudes decompose into SU(2) nj- symbols at the vertices and integrals over boosts at the edges. The integrals define edge amplitudes that can be evaluated analytically using and adapting results in the literature, leading to a pure state sum model formulation. This procedure introduces virtual representations which, in a manner reminiscent of virtual momenta in Feynman amplitudes, are off-shell of the simplicity constraints present in the theory, but with the integrands that peak at the on-shell values. We point out some properties of the edge amplitudes which are helpful for numerical and analytical evaluations of spin foam amplitudes, and suggest among other things a simpler model useful for calculations of certain lowest order amplitudes. As an application, we estimate the large spin scaling behaviour of the simpler model, on a closed foam with all 4-valent edges and Euler characteristic χ , to be Nχ -5 E +V /2. The paper contains a review and an extension of the results on SL (2 ,ℂ ) Clebsch-Gordan coefficients among unitary representations of the principal series that can be useful beyond their application to quantum gravity considered here.

  6. Green infrastructure monitoring in Camden, NJ

    Science.gov (United States)

    The Camden County Municipal Utilities Authority (CCMUA) installed green infrastructure Stormwater Control Measures (SCMs) at multiple locations around the city of Camden, NJ. The SCMs include raised downspout planter boxes, rain gardens, and cisterns. The cisterns capture water ...

  7. EnviroAtlas - Paterson, NJ - Block Groups

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset is the base layer for the Paterson, NJ EnviroAtlas area. The block groups are from the US Census Bureau and are included/excluded based on...

  8. Influence of DX centers on HEMT performance

    Energy Technology Data Exchange (ETDEWEB)

    Munoz, E.; Calleja, E.; Garcia, F.; Izpura, I.; Sanchez Rojas, J.L. (Universidad Politecnica de Madrid (Spain))

    The deep states (DX centers) generated by donors in AlGaAs semiconductor layers cause low-frequency instabilities and low temperature limitations in High Electron Mobility Transistor (HEMT) devices. Under the light of present understanding of donors in III-V semiconductors, the deleterious effects of DX centers on AlGaAs-based HEMT's are reviewed. Trapping effects at low temperature are discussed in relation to the collapse effect in HEMT's. Techniques to minimize such effects are presented. Advanced HEMT designs are shown, including the use of alternative III-V alloys. Some problems in relation with proper modeling of DX centers in HEMT's are described.

  9. Hand-held personal digital assistant program for the HEMOCHRON RxDx heparin and protamine dosing system.

    Science.gov (United States)

    El Rouby, Soumaya; Rinehart, Kristin; Zucker, Marcia L; LaDuca, Frank M

    2003-09-01

    The use of in vitro dosing assays for heparin and protamine during cardiac surgery has significantly improved overall postoperative patient outcome. The HEMOCHRON RxDx system (International Technidyne Corp, Edison, NJ) is widely used for anticoagulation management. Based on a series of consecutive in vitro tests, the RxDx system is used to quantify the patient's heparin requirement (heparin response test, HRT), measure the activated clotting time (ACT), calculate the blood heparin concentration and the required protamine dose (protamine response test, PRT), as well as determine the efficacy of heparin reversal (protamine dose assay, PDA-O). A hand-held personal digital assistant (PDA) program has been developed that performs the RxDx calculations used for anticoagulation management during cardiac surgery. The Palm m505 hand-held device (Palm, Inc., Santa Clara, CA) is used in concert with any standard Hemochron blood coagulation system. The Palm m505 device has been programmed to perform all the calculations required for the RxDx test system. Patient's body weight, height, and gender are entered into the program using the onscreen keypad and the template provided in the Hemochron program. The calculator automatically provides the patient's blood volume and the recommended heparin dose upon entering the baseline ACT and HRT values and a target ACT. At the end of the case, the optimal protamine dose is determined, and the total heparin level is calculated and displayed upon entry of ACT and PRT clotting times. Following protamine administration, the program calculates any additional protamine required to neutralize residual heparin using the data from a PDA-O test. The RxDx hand-held PDA is accurate, quick, simple, and easy to use, patient data are saved and can be retrieved. The inclusion of this rapid computing technology into the Hemochron RxDx system serves to expand the applications of the Hemochron RxDx system during cardiac interventions.

  10. 78 FR 44433 - Safety Zone; Metedeconk River; Brick Township, NJ

    Science.gov (United States)

    2013-07-24

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Metedeconk River; Brick Township, NJ AGENCY... regulation applies to only one recurring fireworks event held in the Metedeconk River in Brick Township, NJ... CFR 165.506, an entry 19 for the Metedeconk River, Brick Township, NJ Safety Zone will be added from...

  11. Identifying factors associated with clinical success in patients treated with NASHA®/Dx injection for fecal incontinence

    Directory of Open Access Journals (Sweden)

    Franklin H

    2016-03-01

    Full Text Available Howard Franklin,1 Andrew C Barrett,1 Ray Wolf2 1Department of Medical Affairs, Salix, a Division of Valeant Pharmaceuticals North America LLC, Bridgewater, NJ, USA; 2Department of Medical Affairs, Valeant Pharmaceuticals North America LLC, Wilton Manors, FL, USA Purpose: Injection with the bulking agent consisting of non-animal stabilized hyaluronic acid/dextranomer (NASHA®/Dx is well tolerated and efficacious for the treatment of fecal incontinence (FI; however, the patient population that may derive maximum benefit has not been established. This post hoc responder analysis assessed demographic and baseline characteristics predictive of responsiveness to NASHA/Dx treatment. Methods: Adults with a Cleveland Clinic Florida fecal incontinence score (CCFIS ≥10 were randomized to receive NASHA/Dx or sham treatment. The primary end point was response to treatment (ie, decrease from baseline of ≥50% in number of FI episodes at 6 months; a prespecified secondary end point was change in fecal incontinence quality of life (FIQL score at 6 months. Post hoc subgroup analyses were performed for baseline and demographic characteristics and prior FI treatments. Results: Overall, response to treatment was significantly greater with NASHA/Dx versus sham injection (52.7% vs 32.1%; P=0.0089. All subgroups analyzed demonstrated evidence of improvement, favoring NASHA/Dx versus sham treatment for both response to treatment and change in the FIQL coping/behavior subscale score. For the primary end point, a significantly greater percentage of patients with CCFIS ≤15, FI symptoms ≤5 years’ duration, or obstetric causes of FI responded to NASHA/Dx treatment versus patients receiving sham treatment (51.1% vs 28.3%, P=0.0169; 55.4% vs 25.7%, P=0.0026; and 53.6% vs 23.1%, P=0.0191, respectively. The mean change in the FIQL coping/behavior score significantly favored NASHA/Dx versus sham treatment for patients with CCFIS ≤15 (P=0.0371, FI symptoms ≤5 years

  12. Sandia and NJ TRANSIT Authority Developing Resilient Power Grid

    Energy Technology Data Exchange (ETDEWEB)

    Hanley, Charles J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Ellis, Abraham [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-11-01

    Through the memorandum of understanding between the Depratment of Energy (DOE), the New Jersey Transit Authority (NJ Transit), and the New Jersey Board of Public Utilities, Sandia National Labs is assisting NJ Transit in developing NJ TransitGrid: an electric microgrid that will include a large-scale gas-fired generation facility and distributed energy resources (photovoltaics [PV], energy storage, electric vehicles, combined heat and power [CHP]) to supply reliable power during storms or other times of significant power failure. The NJ TransitGrid was awarded $410M from the Department of Transportation to develop a first-of-its-kind electric microgrid capable of supplying highly-reliable power.

  13. 78 FR 3836 - Drawbridge Operation Regulation; Shark River, Avon, NJ

    Science.gov (United States)

    2013-01-17

    ... SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulation; Shark River, Avon, NJ AGENCY: Coast... which are across the Shark River (South Channel), at Avon Township, NJ. This deviation is necessary to facilitate machinery replacement on the Shark River railroad bridge. This temporary deviation will allow...

  14. 78 FR 77591 - Drawbridge Operation Regulation; Shark River, NJ

    Science.gov (United States)

    2013-12-24

    ... SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulation; Shark River, NJ AGENCY: Coast Guard... Shark River (South Channel), mile 0.8, at Belmar, NJ. The deviation is necessary to facilitate the... facilitate the replacement of motor seals and instrumentation on the bridge. The Route 71 Bridge across...

  15. 77 FR 57022 - Drawbridge Operation Regulation; Shark River, Avon, NJ

    Science.gov (United States)

    2012-09-17

    ... SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulation; Shark River, Avon, NJ AGENCY: Coast..., and the S35 bridge, mile 0.9, all of which are across the Shark River (South Channel), at Avon Township, NJ. This deviation is necessary to facilitate stringer replacement on the Shark River...

  16. 75 FR 52463 - Safety Zone; Raccoon Creek, Bridgeport, NJ

    Science.gov (United States)

    2010-08-26

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Raccoon Creek, Bridgeport, NJ AGENCY: Coast... specified waters of Raccoon Creek, Bridgeport, NJ. This action is necessary to provide for the safety of... intended to restrict vessel access in order to protect mariners in a portion of Raccoon Creek. DATES: This...

  17. Cistern Performance for Stormwater Management in Camden, NJ - presentation

    Science.gov (United States)

    The Camden County Municipal Utilities Authority (CCMUA) installed different types of green infrastructure Stormwater Control Measures (SCMs) at locations around the city of Camden, NJ. The installed SCMs include cisterns. Cisterns provide a cost effective approach to reduce st...

  18. First year update on green infrastructure monitoring in Camden, NJ

    Science.gov (United States)

    The Camden County Municipal Utilities Authority (CCMUA) installed green infrastructure Stormwater Control Measures (SCMs) at multiple locations around the city of Camden, NJ. The SCMs include raised downspout planter boxes, rain gardens, and cisterns. The cisterns capture water ...

  19. First year results on cistern monitoring in Camden, NJ

    Science.gov (United States)

    The Camden County Municipal Utilities Authority (CCMUA) installed green infrastructure Stormwater Control Measures (SCMs) at multiple locations around the city of Camden, NJ. The SCMs include raised downspout planter boxes, rain gardens, and cisterns. The cisterns capture water ...

  20. Cistern Performance for Stormwater Management in Camden, NJ - abstract

    Science.gov (United States)

    The Camden County Municipal Utilities Authority (CCMUA) installed different types of green infrastructure Stormwater Control Measures (SCMs) at locations around the city of Camden, NJ. The installed SCMs include cisterns. Cisterns provide a cost effective approach to reduce st...

  1. EnviroAtlas - Paterson, NJ - Atlas Area Boundary

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset shows the boundary of the Paterson, NJ Atlas Area. It represents the outside edge of all the block groups included in the EnviroAtlas Area....

  2. Recent papers from DX-1, detonation science and technology

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    Over the past year members of DX-1 have participated in several conferences where presentations were made and papers prepared for proceedings. There have also been several papers published in or submitted to refereed journals for publication. Rather that attach all these papers to the DX-1 Quarterly Report, we decided to put them in a Los Alamos report that could be distributed to those who get the quarterly, as well as others that have an interest in the work being done in DX-1 both inside and outside the Laboratory. This compilation does not represent all the work reported during the year because some people have chosen not to include their work here. In particular, there were a number of papers relating to deflagration-to-detonation modeling that were not included. However, this group of papers does present a good picture of much of the unclassified work being done in DX-1. Several of the papers include coauthors from other groups or divisions at the Laboratory, providing an indication of the collaborations in which people in DX-1 are involved. Discussed topics of submitted papers include: shock compression of condensed matter, pyrotechnics, shock waves, molecular spectroscopy, sound speed measurements in PBX-9501, chemical dimerization, and micromechanics of spall and damage in tantalum.

  3. Concerning the Integral dx/x[superscript m] (1+x)

    Science.gov (United States)

    Walters, William; Huber, Michael

    2010-01-01

    Consider the integral dx/x[superscript m] (1+x). In the "CRC Standard Mathematical Tables," this integral can require repeated integral evaluations. Enter this integral into your favourite computer algebra system, and the results may be unrecognizable. In this article, we seek to provide a simpler evaluation for integrals of this form. We state up…

  4. Concerning the Integral dx/x[superscript m] (1+x)

    Science.gov (United States)

    Walters, William; Huber, Michael

    2010-01-01

    Consider the integral dx/x[superscript m] (1+x). In the "CRC Standard Mathematical Tables," this integral can require repeated integral evaluations. Enter this integral into your favourite computer algebra system, and the results may be unrecognizable. In this article, we seek to provide a simpler evaluation for integrals of this form. We state up…

  5. Evaluation of the Beckman Coulter UniCel DxH 800 and Abbott Diagnostics Cell-Dyn Sapphire hematology analyzers on pediatric and neonatal specimens in a tertiary care hospital.

    Science.gov (United States)

    Tan, Brent T; Nava, Armando J; George, Tracy I

    2011-06-01

    We evaluated the new UniCel DxH 800 hematology analyzer (Beckman Coulter, Miami, FL) vs the Cell-Dyn Sapphire (Abbott Diagnostics, Santa Clara, CA) using 156 pediatric specimens in Microtainer tubes (Becton Dickinson, Franklin Lakes, NJ). The CBC and differential showed good interinstrument correlation, including WBCs (r = 0.995), RBCs (r = 0.992), hemoglobin (r = 0.998), mean corpuscular volume (r = 0.988), platelets (r = 0.997), neutrophils (r = 0.988), lymphocytes (r = 0.984), monocytes (r = 0.815), eosinophils (r = 0.840), basophils (r = 0.049), and nucleated RBCs (NRBCs; r = 0.906). In the instrument vs 400-cell manual differential comparison, the DxH 800 and Sapphire showed comparable performance for nearly all parameters except for NRBCs, for which the DxH 800 correlated better (r = 0.989) than the Sapphire (r = 0.906). We also compared clinical efficiency by determining whether flagged specimens showed abnormalities on a peripheral blood smear as defined by International Council for Standardization in Haematology criteria. The efficiency of the DxH 800 was 78.0% vs the Sapphire at 68.1%. Both instruments showed identical sensitivity (91.1%), but the specificity for the DxH 800 (71.9%) was higher than that of the Sapphire (57.3%).

  6. Cistern Performance for Stormwater Management in Camden, NJ

    Science.gov (United States)

    The Camden County Municipal Utilities Authority (CCMUA) installed cisterns at locations around the city of Camden, NJ. Cisterns provide a cost effective approach to reduce stormwater runoff volume and peak discharge. The collected water can be substituted for potable water in s...

  7. 75 FR 13681 - Television Broadcasting Services; Atlantic City, NJ

    Science.gov (United States)

    2010-03-23

    ... COMMISSION 47 CFR Part 73 Television Broadcasting Services; Atlantic City, NJ AGENCY: Federal Communications... amended, to allocate not less than one very high frequency commercial television channel to each State, if... Review Act, see 5 U.S.C. 801(a)(1)(A). List of Subjects in 47 CFR Part 73 Television,...

  8. 78 FR 7848 - New Jersey Disaster Number NJ-00033

    Science.gov (United States)

    2013-02-04

    ... ADMINISTRATION New Jersey Disaster Number NJ-00033 AGENCY: U.S. Small Business Administration. ACTION: Amendment...: U.S. Small Business Administration, Processing and Disbursement Center, 14925 Kingsport Road, Fort... Business Administration, 409 3rd Street SW., Suite 6050, Washington, DC 20416. SUPPLEMENTARY...

  9. 76 FR 60732 - Drawbridge Operation Regulations; Navesink (Swimming) River, NJ

    Science.gov (United States)

    2011-09-30

    ... SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Navesink (Swimming) River, NJ AGENCY... the Oceanic Bridge at mile 4.5 across the Navesink (Swimming) River between Oceanic and Locust Point...-9826. SUPPLEMENTARY INFORMATION: The Oceanic Bridge, across the Navesink (Swimming) River, mile 4.5...

  10. 75 FR 38712 - Drawbridge Operation Regulation; Shrewsbury River, NJ

    Science.gov (United States)

    2010-07-06

    ... SECURITY Coast Guard 33 CFR Part 117 RIN 1625-AA09 Drawbridge Operation Regulation; Shrewsbury River, NJ... operation regulations that govern the operation of the Route 36 Bridge at mile 1.8, across the Shrewsbury... operation regulations for the Route 36 Bridge at mile 1.8, across the Shrewsbury River at Highlands,...

  11. Rescuing the nonjet (NJ) azimuth quadrupole from the flow narrative

    CERN Document Server

    Trainor, Thomas A

    2016-01-01

    According to the flow narrative commonly applied to high-energy nuclear collisions a cylindrical-quadrupole component of 1D azimuth angular correlations is conventionally denoted by quantity $v_2$ and interpreted to represent elliptic flow. Jet angular correlations may also contribute to $v_2$ data as "nonflow" depending on the method used to calculate $v_2$, but 2D graphical methods are available to insure accurate separation. The nonjet (NJ) quadrupole has various properties inconsistent with a flow interpretation, including the observation that NJ quadrupole centrality variation in A-A collisions has no relation to strongly-varying jet modification ("jet quenching") in those collisions commonly attributed to jet interaction with a flowing dense medium. In this presentation I describe isolation of quadrupole spectra from pt-differential $v_2(p_t)$ data from the RHIC and LHC. I demonstrate that quadrupole spectra have characteristics very different from the single-particle spectra for most hadrons, that quad...

  12. Complete genome sequence of Aggregatibacter (Haemophilus) aphrophilus NJ8700.

    Science.gov (United States)

    Di Bonaventura, Maria Pia; DeSalle, Rob; Pop, Mihai; Nagarajan, Niranjan; Figurski, David H; Fine, Daniel H; Kaplan, Jeffrey B; Planet, Paul J

    2009-07-01

    We report the finished and annotated genome sequence of Aggregatibacter aphrophilus strain NJ8700, a strain isolated from the oral flora of a healthy individual, and discuss characteristics that may affect its dual roles in human health and disease. This strain has a rough appearance, and its genome contains genes encoding a type VI secretion system and several factors that may participate in host colonization.

  13. Complete Genome Sequence of Aggregatibacter (Haemophilus) aphrophilus NJ8700▿

    Science.gov (United States)

    Di Bonaventura, Maria Pia; DeSalle, Rob; Pop, Mihai; Nagarajan, Niranjan; Figurski, David H.; Fine, Daniel H.; Kaplan, Jeffrey B.; Planet, Paul J.

    2009-01-01

    We report the finished and annotated genome sequence of Aggregatibacter aphrophilus strain NJ8700, a strain isolated from the oral flora of a healthy individual, and discuss characteristics that may affect its dual roles in human health and disease. This strain has a rough appearance, and its genome contains genes encoding a type VI secretion system and several factors that may participate in host colonization. PMID:19447908

  14. NATURAL ATTENUATION FOR ECOSYSTEM RESTORATION IN NY/NJ HARBOR

    Energy Technology Data Exchange (ETDEWEB)

    Van der Lelie, D.; Reid-Green, J. D.; Stern, E. A.

    2003-12-31

    We have investigated the feasibility of using natural attenuation methods for ecosystem restoration in New York/New Jersey Harbor. Measurements were made of the most probable number of sulfate-reducing bacteria (SRB) in native sediments and in samples, which had been supplemented with an appropriate electron donor and electron acceptor. The results showed that the activity of the endogenous microbial population in the native sediment was high enough to make possible adequate chemical transformation rates. The bioavailability of the zinc in the sediments was measured using the BIOMET biosensor technique. The bioavailability of the zinc was effectively eliminated following the microbial activities. We concluded that natural attenuation could be used effectively in treating sediments from Newark Bay and surrounding waters and that the resultant materials could likely be used in environmental restoration projects of the type proposed for construction in South Kearny, NJ.

  15. 77 FR 55455 - Foreign-Trade Zone 235-Lakewood, NJ, Authorization of Production Activity, Cosmetic Essence...

    Science.gov (United States)

    2012-09-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Foreign-Trade Zone 235--Lakewood, NJ, Authorization of Production Activity, Cosmetic Essence Innovations, LLC, (Fragrance Bottling), Holmdel, NJ Cosmetic Essence Innovations, LLC...

  16. How to Use the DX SYSTEM of Diagnostic Testing. Methodology Project.

    Science.gov (United States)

    McArthur, David; Cabello, Beverly

    The DX SYSTEM of Diagnostic Testing is an easy-to-use computerized system for developing and administering diagnostic tests. A diagnostic test measures a student's mastery of a specific domain (skill or content area). It examines the necessary subskills hierarchically from the most to the least complex. The DX SYSTEM features tailored testing with…

  17. ONCOLOGISTS' BARRIERS AND FACILITATORS FOR ONCOTYPE DX USE: QUALITATIVE STUDY.

    Science.gov (United States)

    Roberts, Megan C; Bryson, Amy; Weinberger, Morris; Dusetzina, Stacie B; Dinan, Michaela A; Reeder-Hayes, Katherine; Wheeler, Stephanie B

    2016-01-01

    Oncotype DX (ODX), a tumor gene profiling test, has been incorporated into clinical guidelines to aid in adjuvant chemotherapy decision making for early-stage, hormone receptor positive breast cancer patients. Despite United States (U.S.) guidelines, less than half of eligible women receive testing. Reasons for low usage are unclear: Our objective was to better understand U.S. oncologists' ODX uptake and how they use ODX during adjuvant chemotherapy decision making. We conducted semi-structured, ~30-minute phone interviews with medical and surgical oncologists in one U.S. State using purposive sampling. Oncologists were included if they saw greater than or equal to five breast cancer patients per week. Recruitment ended upon thematic saturation. Interviews were recorded, transcribed, and double-coded using template analysis. During analysis, themes emerged across three domains. First, organizational factors (i.e., departmental structure, ODX marketing, and medical/insurance guidelines) influenced ease of ODX use. Second, oncologists referenced the influence of interpersonal factors (e.g., normative beliefs and peer use of ODX) over their own practices and recommendations. Third, intrapersonal factors (e.g., oncologist attitudes, perceived barriers, and research gaps) were discussed: although oncologists largely held positive attitudes about ODX, they reported challenges with interpreting intermediate scores for treatment decisions and explaining test results to patients. Finally, oncologists identified several research gaps. As more tumor gene profiling tests are incorporated into cancer care for treatment decision making, it is important to understand their use in clinical practice. This study identified multi-level factors that influence ODX uptake into clinical practice, providing insights into facilitators and modifiable barriers that can be leveraged for improving ODX uptake to aid treatment decision making.

  18. Clinical roundtable monograph: a multidisciplinary approach to the use of oncotype DX in clinical practice.

    Science.gov (United States)

    Gradishar, William J; Hansen, Nora M; Susnik, Barbara

    2009-04-01

    Recently, recommendations for the use of the Oncotype DX assay in estrogen receptor-positive node-negative breast cancer patients were incorporated into guidelines from both the American Society of Clinical Oncology and the National Comprehensive Cancer Network. The Oncotype DX assay is a diagnostic test which measures changes in a set of 21 genes in order to predict the likelihood of disease recurrence and also to predict which patients are most likely to respond to chemotherapy. Oncotype DX has been available commercially since January 2004 and has been used for more than 85,000 patients. Drs. William J. Gradishar, Nora M. Hansen, and Barbara Susnik answered questions regarding the incorporation of the Oncotype DX breast cancer assay into routine clinical practice. This expert dialog offers an update and clinical insights into when, how, and why clinicians might incorporate the Oncotype DX assay into the management of their breast cancer patients. Also, the latest research into the benefit of the Oncotype DX assay in node-positive patients is discussed. Finally, sample case studies offer clinically relevant examples of the practical application of the Oncotype DX assay.

  19. The Hemochron Response RxDx heparin and protamine dosing system.

    Science.gov (United States)

    Jaryno, Stacy A; Zucker, Marcia L; LaDuca, Frank M

    2004-09-01

    The use of dosing assays to calculate heparin and protamine dose requirements during cardiac surgery has been shown to significantly improve overall postoperative patient outcome. When patients are managed with an individualized dosing system, intraoperative and postoperative transfusion requirements and bleeding are reduced. The Hemochron RxDx system is widely used as a complement to traditional activated clotting time testing to optimize anticoagulation management. The system consists of the heparin response test, the protamine response test, and the protamine dose assay. All are modifications of the activated clotting time using either Celite (Celite Corporation, Santa Barbara, CA) or kaolin as the activator. Dosing is calculated manually using earlier version Hemochron instruments (model 801) or automatically with the Hemochron 8000 or with the early versions of the Hemochron Response and the personal digital assistant (PDA) RxDx calculator. Missing from available user options is an automated RxDx system for the Response. A study was conducted at four clinical sites to compare recently developed Response RxDx software, which eliminates the need for the PDA RxDx calculator, to the existing Hemochron 8000 RxDx and to the Response-PDA RxDx systems. Similar to the current system, the operator inputs the patient's height, weight, and gender, and the software automatically calculates the blood volume. Using the clotting times determined on the Response, bolus heparin and protamine doses and any additional heparin and protamine requirements are calculated automatically. Data were collected from 76 patients, of which, 64 patients were on pump, 11 patients were off pump, and 1 patient was converted from off to on pump. The Response estimated blood volume calculations showed a correlation coefficient of 0.989 when compared with available systems. A good correlation was also observed for the bolus heparin (r = 0.925) and protamine doses (r = 0.900) with equivalence

  20. 75 FR 54026 - Safety Zone; Red Bull Flugtag, Delaware River, Camden, NJ

    Science.gov (United States)

    2010-09-03

    ... safety zone in an area of the Delaware River, Camden, NJ, described as North of the Wiggins park Marina... traffic from navigating on the Delaware River in an area described as north of the Wiggins Park Marina...

  1. An improved method for measuring muon energy using the truncated mean of dE/dx

    CERN Document Server

    Abbasi, R; Ackermann, M; Adams, J; Aguilar, J A; Ahlers, M; Altmann, D; Andeen, K; Auffenberg, J; Bai, X; Baker, M; Barwick, S W; Baum, V; Bay, R; Beattie, K; Beatty, J J; Bechet, S; Tjus, J Becker; Becker, K -H; Bell, M; Benabderrahmane, M L; BenZvi, S; Berdermann, J; Berghaus, P; Berley, D; Bernardini, E; Bertrand, D; Besson, D Z; Bindig, D; Bissok, M; Blaufuss, E; Blumenthal, J; Boersma, D J; Bohm, C; Bose, D; Böser, S; Botner, O; Brayeur, L; Brown, A M; Bruijn, R; Brunner, J; Buitink, S; Carson, M; Casey, J; Casier, M; Chirkin, D; Christy, B; Clevermann, F; Cohen, S; Cowen, D F; Silva, A H Cruz; Danninger, M; Daughhetee, J; Davis, J C; De Clercq, C; Descamps, F; Desiati, P; de Vries-Uiterweerd, G; DeYoung, T; Díaz-Vélez, J C; Dreyer, J; Dumm, J P; Dunkman, M; Eagan, R; Eisch, J; Elliott, C; Ellsworth, R W; Engdegård, O; Euler, S; Evenson, P A; Fadiran, O; Fazely, A R; Fedynitch, A; Feintzeig, J; Feusels, T; Filimonov, K; Finley, C; Fischer-Wasels, T; Flis, S; Franckowiak, A; Franke, R; Frantzen, K; Fuchs, T; Gaisser, T K; Gallagher, J; Gerhardt, L; Gladstone, L; Glüsenkamp, T; Goldschmidt, A; Goodman, J A; Góra, D; Grant, D; Groß, A; Grullon, S; Gurtner, M; Ha, C; Ismail, A Haj; Hallgren, A; Halzen, F; Hanson, K; Heereman, D; Heimann, P; Heinen, D; Helbing, K; Hellauer, R; Hickford, S; Hill, G C; Hoffman, K D; Hoffmann, R; Homeier, A; Hoshina, K; Huelsnitz, W; Hulth, P O; Hultqvist, K; Hussain, S; Ishihara, A; Jacobi, E; Jacobsen, J; Japaridze, G S; Jlelati, O; Kappes, A; Karg, T; Karle, A; Kiryluk, J; Kislat, F; Kläs, J; Klein, S R; Klepser, S; Köhne, J -H; Kohnen, G; Kolanoski, H; Köpke, L; Kopper, C; Kopper, S; Koskinen, D J; Kowalski, M; Krasberg, M; Kroll, G; Kunnen, J; Kurahashi, N; Kuwabara, T; Labare, M; Laihem, K; Landsman, H; Larson, M J; Lauer, R; Lesiak-Bzdak, M; Lünemann, J; Madsen, J; Maruyama, R; Mase, K; Matis, H S; McDermott, A; McNally, F; Meagher, K; Merck, M; Mészáros, P; Meures, T; Miarecki, S; Middell, E; Milke, N; Miller, J; Mohrmann, L; Montaruli, T; Morse, R; Movit, S M; Nahnhauer, R; Naumann, U; Nießen, P; Nowicki, S C; Nygren, D R; Obertacke, A; Odrowski, S; Olivas, A; Olivo, M; O'Murchadha, A; Panknin, S; Paul, L; Pepper, J A; Heros, C Pérez de los; Pieloth, D; Pirk, N; Posselt, J; Price, P B; Przybylski, G T; Rädel, L; Rawlins, K; Redl, P; Resconi, E; Rhode, W; Ribordy, M; Richman, M; Riedel, B; Rodrigues, J P; Roth, J; Rothmaier, F; Rott, C; Roucelle, C; Ruhe, T; Ruzybayev, B; Ryckbosch, D; Saba, S M; Salameh, T; Sander, H -G; Santander, M; Sarkar, S; Schatto, K; Scheel, M; Scheriau, F; Schmidt, T; Schmitz, M; Schoenen, S; Schöneberg, S; Schönherr, L; Schönwald, A; Schukraft, A; Schulte, L; Schulz, O; Seckel, D; Seo, S H; Sestayo, Y; Seunarine, S; Shulman, L; Smith, M W E; Soiron, M; Soldin, D; Spiczak, G M; Spiering, C; Stamatikos, M; Stanev, T; Stasik, A; Stezelberger, T; Stokstad, R G; Stößl, A; Stoyanov, S; Strahler, E A; Ström, R; Sulanke, K-H; Sullivan, G W; Taavola, H; Taboada, I; Tamburro, A; Ter-Antonyan, S; Tilav, S; Toale, P A; Toscano, S; Usner, M; van der Drift, D; van Eijndhoven, N; Van Overloop, A; van Santen, J; Vehring, M; Voge, M; Walck, C; Waldenmaier, T; Wallraff, M; Walter, M; Wasserman, R; Weaver, Ch; Wendt, C; Westerhoff, S; Whitehorn, N; Wiebe, K; Wiebusch, C H; Williams, D R; Wissing, H; Wolf, M; Wood, T R; Woschnagg, K; Xu, C; Xu, D L; Xu, X W; Yanez, J P; Yodh, G; Yoshida, S; Zarzhitsky, P; Ziemann, J; Zilles, A; Zoll, M

    2012-01-01

    The measurement of muon energy is critical for many analyses in large Cherenkov detectors, particularly those that involve separating extraterrestrial neutrinos from the atmospheric neutrino background. Muon energy has traditionally been determined by measuring the specific energy loss (dE/dx) along the muon's path and relating the dE/dx to the muon energy. Because high-energy muons (E_mu > 1 TeV) lose energy randomly, the spread in dE/dx values is quite large, leading to a typical energy resolution of 0.29 in log10(E_mu) for a muon observed over a 1 km path length in the IceCube detector. In this paper, we present an improved method that uses a truncated mean and other techniques to determine the muon energy. The muon track is divided into separate segments with individual dE/dx values. The elimination of segments with the highest dE/dx results in an overall dE/dx that is more closely correlated to the muon energy. This method results in an energy resolution of 0.22 in log10(E_mu), which gives a 26% improvem...

  2. Formation of DX-centers in indium doped CdTe

    Energy Technology Data Exchange (ETDEWEB)

    Tuerker, M.; Kronenberg, J.; Deicher, M., E-mail: manfred.deicher@tech-phys.uni-sb.de; Wolf, H.; Wichert, Th. [Universitaet des Saarlandes, Technische Physik (Germany)

    2007-06-15

    In CdTe, the achievable n-type doping is limited by the formation of DX-centers. A characteristic feature of DX-centers is the 'persistent photoconductivity (PPC)' which is created by illumination at low temperatures and caused by a metastable state of the DX-center. The DX-center and the PPC effect in n-type CdTe are theoretically explained by the 'large lattice relaxation model'. PAC measurements on In doped CdTe using {sup 111}In/{sup 111}Cd and, in addition, resistivity measurements on the same samples have been performed. Below 150 K, the samples showed a PPC effect that was accompanied by an increase of about 20% of the carrier concentration. This effect is not accompanied by any changes of the observed EFG. Possible explanations of the EFG observed, originally assigned to the DX-center, will be discussed. Finally, first reports on the investigation of DX-centers in CdTe using the radioactive isotope {sup 117}Cd decaying to {sup 117}In are presented.

  3. An improved method for measuring muon energy using the truncated mean of dE/dx

    Science.gov (United States)

    Abbasi, R.; Abdou, Y.; Ackermann, M.; Adams, J.; Aguilar, J. A.; Ahlers, M.; Altmann, D.; Andeen, K.; Auffenberg, J.; Bai, X.; Baker, M.; Barwick, S. W.; Baum, V.; Bay, R.; Beattie, K.; Beatty, J. J.; Bechet, S.; Becker Tjus, J.; Becker, K.-H.; Bell, M.; Benabderrahmane, M. L.; BenZvi, S.; Berdermann, J.; Berghaus, P.; Berley, D.; Bernardini, E.; Bertrand, D.; Besson, D. Z.; Bindig, D.; Bissok, M.; Blaufuss, E.; Blumenthal, J.; Boersma, D. J.; Bohm, C.; Bose, D.; Böser, S.; Botner, O.; Brayeur, L.; Brown, A. M.; Bruijn, R.; Brunner, J.; Buitink, S.; Carson, M.; Casey, J.; Casier, M.; Chirkin, D.; Christy, B.; Clevermann, F.; Cohen, S.; Cowen, D. F.; Cruz Silva, A. H.; Danninger, M.; Daughhetee, J.; Davis, J. C.; De Clercq, C.; Descamps, F.; Desiati, P.; de Vries-Uiterweerd, G.; DeYoung, T.; Díaz-Vélez, J. C.; Dreyer, J.; Dumm, J. P.; Dunkman, M.; Eagan, R.; Eisch, J.; Ellsworth, R. W.; Engdegård, O.; Euler, S.; Evenson, P. A.; Fadiran, O.; Fazely, A. R.; Fedynitch, A.; Feintzeig, J.; Feusels, T.; Filimonov, K.; Finley, C.; Fischer-Wasels, T.; Flis, S.; Franckowiak, A.; Franke, R.; Frantzen, K.; Fuchs, T.; Gaisser, T. K.; Gallagher, J.; Gerhardt, L.; Gladstone, L.; Glüsenkamp, T.; Goldschmidt, A.; Goodman, J. A.; Góra, D.; Grant, D.; Groß, A.; Grullon, S.; Gurtner, M.; Ha, C.; Haj Ismail, A.; Hallgren, A.; Halzen, F.; Hanson, K.; Heereman, D.; Heimann, P.; Heinen, D.; Helbing, K.; Hellauer, R.; Hickford, S.; Hill, G. C.; Hoffman, K. D.; Hoffmann, R.; Homeier, A.; Hoshina, K.; Huelsnitz, W.; Hulth, P. O.; Hultqvist, K.; Hussain, S.; Ishihara, A.; Jacobi, E.; Jacobsen, J.; Japaridze, G. S.; Jlelati, O.; Kappes, A.; Karg, T.; Karle, A.; Kiryluk, J.; Kislat, F.; Kläs, J.; Klein, S. R.; Köhne, J.-H.; Kohnen, G.; Kolanoski, H.; Köpke, L.; Kopper, C.; Kopper, S.; Koskinen, D. J.; Kowalski, M.; Krasberg, M.; Kroll, G.; Kunnen, J.; Kurahashi, N.; Kuwabara, T.; Labare, M.; Laihem, K.; Landsman, H.; Larson, M. J.; Lauer, R.; Lesiak-Bzdak, M.; Lünemann, J.; Madsen, J.; Maruyama, R.; Mase, K.; Matis, H. S.; McNally, F.; Meagher, K.; Merck, M.; Mészáros, P.; Meures, T.; Miarecki, S.; Middell, E.; Milke, N.; Miller, J.; Mohrmann, L.; Montaruli, T.; Morse, R.; Movit, S. M.; Nahnhauer, R.; Naumann, U.; Nowicki, S. C.; Nygren, D. R.; Obertacke, A.; Odrowski, S.; Olivas, A.; Olivo, M.; O'Murchadha, A.; Panknin, S.; Paul, L.; Pepper, J. A.; Pérez de los Heros, C.; Pieloth, D.; Pirk, N.; Posselt, J.; Price, P. B.; Przybylski, G. T.; Rädel, L.; Rawlins, K.; Redl, P.; Resconi, E.; Rhode, W.; Ribordy, M.; Richman, M.; Riedel, B.; Rodrigues, J. P.; Rothmaier, F.; Rott, C.; Ruhe, T.; Ruzybayev, B.; Ryckbosch, D.; Saba, S. M.; Salameh, T.; Sander, H.-G.; Santander, M.; Sarkar, S.; Schatto, K.; Scheel, M.; Scheriau, F.; Schmidt, T.; Schmitz, M.; Schoenen, S.; Schöneberg, S.; Schönherr, L.; Schönwald, A.; Schukraft, A.; Schulte, L.; Schulz, O.; Seckel, D.; Seo, S. H.; Sestayo, Y.; Seunarine, S.; Smith, M. W. E.; Soiron, M.; Soldin, D.; Spiczak, G. M.; Spiering, C.; Stamatikos, M.; Stanev, T.; Stasik, A.; Stezelberger, T.; Stokstad, R. G.; Stößl, A.; Strahler, E. A.; Ström, R.; Sullivan, G. W.; Taavola, H.; Taboada, I.; Tamburro, A.; Ter-Antonyan, S.; Tilav, S.; Toale, P. A.; Toscano, S.; Usner, M.; van der Drift, D.; van Eijndhoven, N.; Van Overloop, A.; van Santen, J.; Vehring, M.; Voge, M.; Walck, C.; Waldenmaier, T.; Wallraff, M.; Walter, M.; Wasserman, R.; Weaver, Ch.; Wendt, C.; Westerhoff, S.; Whitehorn, N.; Wiebe, K.; Wiebusch, C. H.; Williams, D. R.; Wissing, H.; Wolf, M.; Wood, T. R.; Woschnagg, K.; Xu, C.; Xu, D. L.; Xu, X. W.; Yanez, J. P.; Yodh, G.; Yoshida, S.; Zarzhitsky, P.; Ziemann, J.; Zilles, A.; Zoll, M.

    2013-03-01

    The measurement of muon energy is critical for many analyses in large Cherenkov detectors, particularly those that involve separating extraterrestrial neutrinos from the atmospheric neutrino background. Muon energy has traditionally been determined by measuring the specific energy loss (dE/dx) along the muon's path and relating the dE/dx to the muon energy. Because high-energy muons (Eμ>1 TeV) lose energy randomly, the spread in dE/dx values is quite large, leading to a typical energy resolution of 0.29 in log10(Eμ) for a muon observed over a 1 km path length in the IceCube detector. In this paper, we present an improved method that uses a truncated mean and other techniques to determine the muon energy. The muon track is divided into separate segments with individual dE/dx values. The elimination of segments with the highest dE/dx results in an overall dE/dx that is more closely correlated to the muon energy. This method results in an energy resolution of 0.22 in log10(Eμ), which gives a 26% improvement. This technique is applicable to any large water or ice detector and potentially to large scintillator or liquid argon detectors.

  4. ∫baf(x)dx=∫baf(a+b-x)dx的应用初探%Exploration of the Application of ∫baf(x) dx = ∫baf(a+ b - x ) dx

    Institute of Scientific and Technical Information of China (English)

    吴琼

    2003-01-01

    本文从两个方面对等式∫baf(x)dx=∫bafa+b-x)dx的应用做了一些初步探讨,这两方面分别为:运用这个等式证明一些积分等式,以及证明一些不易求解的三角函数积分.

  5. Field test study of DX piles%DX桩群桩现场试验研究

    Institute of Scientific and Technical Information of China (English)

    陈立宏; 唐松涛; 贺德新

    2011-01-01

    DX桩(三岔双向挤扩灌注桩)作为一种新型的变截面桩型在承载力和沉降方面比普通直孔灌注桩具有明显的优势.但对于DX桩的承载机制和沉降特性的研究,特别是DX桩群桩的研究还不充分.主要通过现场的模型桩试验,对DX桩单桩和群桩的承载力和沉降特性进行了研究.分析了相同条件下单桩和群桩的特性,同时比较了相同桩长、桩径以及相同承载力条件下DX桩和直孔桩的差异,为DX桩的设计提供了参考.%Cast-in-place pile with expanded branches and bells by 3-way extruding arms (DX pile), a new variable cross-section pile,has obvious advantages in bearing capacity and settlement control compared to conventional pile.However, studies of bearing mechanism and settlement characteristic.especially group DX piles.are not sufficient.The bearing capacity and settlement characteristics of single DX pilc and group DX piles are analyzed via in-situ model test.Special attention is paid on single and group DX piles comparison under same conditions; at the meantime, the single DX pile and conventional pile with the same pile length,diameter, and the same bearing capacity are compared so as to provide the theoretical references for the bearing capacity design of the DX piles in the engineering practice.

  6. OpenDx programs for visualization of computational fluid dynamics (CFD) simulations; Programas para visualizacao de simulacoes computacionais de dinamica de fluidos (CFD) usando o OpenDx

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Marcelo Mariano da

    2008-01-15

    The search for high performance and low cost hardware and software solutions always guides the developments performed at the IEN parallel computing laboratory. In this context, this dissertation about the building of programs for visualization of computational fluid dynamics (CFD) simulations using the open source software OpenDx was written. The programs developed are useful to produce videos and images in two or three dimensions. They are interactive, easily to use and were designed to serve fluid dynamics researchers. A detailed description about how this programs were developed and the complete instructions of how to use them was done. The use of OpenDx as development tool is also introduced. There are examples that help the reader to understand how programs can be useful for many applications. (author)

  7. The binding of (3H)AF-DX 384 to rat ileal smooth muscle muscarinic receptors

    Energy Technology Data Exchange (ETDEWEB)

    Entzeroth, M.; Mayer, N. (Department of Biochemical Research, Dr. Karl Thomae GmbH Biberach (West Germany))

    1991-01-01

    The tritiated cardioselective muscarinic antagonist AF-DX 384 (5,11-dihydro-11-(2-(-(8-dipropylamino)methyl)-1-piperidinyl-ethyl-amino-carbonyl)-6H-pyrido (2,3-b) (1,4)benzodiazepin-6-one) was used to label muscarinic receptors in the rat ileum. Saturation binding to membrane suspensions revealed a high affinity binding site with a Kd of 9.2 nM. The maximal number of binding sites labeled in this tissue (Bmax) is 237 fmol/mg protein. The association and dissociation kinetics were well represented by single exponential reactions, and the dissociation constant obtained from the ratio of rate constants was in agreement with that derived from saturation experiments. Specific binding was inhibited by muscarinic antagonists with a rank order of potencies of atropine (pKi: 8.80) greater than 4-DAMP (pKi: 8.23) = AF-DX 384 (pKi: 8.20) greater than AF-DX 116 (pKi: 7.09) = hexahydro-sila-difenidol (pKi: 6.97) greater than pirenzepine (pKi: 6.49) and is consistent with the interaction of (3H)AF-DX 384 with muscarinic receptors of the M2 subtype. It can be concluded that (3H)AF-DX 384 can be used to selectively label M2 muscarinic receptors in heterogeneous receptor populations.

  8. PEGylated DX-1000: Pharmacokinetics and Antineoplastic Activity of a Specific Plasmin Inhibitor

    Directory of Open Access Journals (Sweden)

    Laetitia Devy

    2007-11-01

    Full Text Available Novel inhibitors of the urokinase-mediated plasminogen (plg activation system are potentially of great clinical benefit as anticancer treatments. Using phage display, we identified DX-1000 a tissue factor pathway inhibitor-derived Kunitz domain protein which is a specific high-affinity inhibitor of plasmin (pin (Ki = 99 pM. When tested in vitro, DX-1000 blocks plasminmediated pro-matrix metal loproteinase-9 (proMMP-9 activation on cells and dose-dependently inhibits tube formation, while not significantly affecting hemostasis and coagulation. However, this low-molecular weight protein inhibitor (~ 7 kDa exhibits rapid plasma clearance in mice and rabbits, limiting its potential clinical use in chronic diseases. After site-specific PEGylation, DX-1000 retains its activity and exhibits a decreased plasma clearance. This PEGylated derivative is effective in vitro, as well as potent in inhibiting tumor growth of green fluorescent protein (GFP-labeled MDA-MB-231 cells. 4PEG-DX-1000 treatment causes a significant reduction of urokinase-type plasminogen activator (uPA and plasminogen expressions, a reduction of tumor proliferation, and vascularization. 4PEG-DX-1000 treatment significantly decreases the level of active mitogenactivated protein kinase (MAPK in the primary tumors and reduces metastasis incidence. Together, our results demonstrate the potential value of plasmin inhibitors as therapeutic agents for blocking breast cancer growth and metastasis.

  9. Experimental study on DX pile performance in frozen soils under lateral loading

    Institute of Scientific and Technical Information of China (English)

    XiaoBing Liu; LiHong Chen; ZhongYang Yu; JianXiao Hu; Wen Peng

    2013-01-01

    Experiments about working mechanism and mechanical characteristics of the DX model pile foundation under lateral dynamic and static loading were conducted by using a model system of the dynamic frozen soil-pile interaction. The horizontal displacement-force relationship of the pile head and bending moment distribution along the body in frozen soils of different temperatures were discussed. According to test results, both the horizontal displacement-force relationship of the DX pile head and bending moment distribution of the DX pile body are smaller than that of equal-diameter piles under same lateral loads. The piles with different plate positions show different displacements and bending moments. This phenomenon is mainly related to the soil temperature and bearing plates locations. Thus, dynamic response analysis of the pile foundation should be taken into account.

  10. Use of modified Magee equations and histologic criteria to predict the Oncotype DX recurrence score.

    Science.gov (United States)

    Turner, Bradley M; Skinner, Kristin A; Tang, Ping; Jackson, Mary C; Soukiazian, Nyrie; Shayne, Michelle; Huston, Alissa; Ling, Marilyn; Hicks, David G

    2015-07-01

    Oncotype DX (Genomic Health, Redwood City, CA, USA, current list price $4,350.00) is a multigene quantitative reverse transcription-polymerase chain reaction-based assay that estimates the risk of distant recurrence and predicts chemotherapy benefit for patients with estrogen receptor (ER)-positive breast cancers. Studies have suggested that standard histologic variables can provide similar information. Klein and Dabbs et al have shown that Oncotype DX recurrence scores can be estimated by incorporating standard histologic variables into equations (Magee equations). Using a simple modification of the Magee equation, we predict the Oncotype DX recurrence score in an independent set of 283 cases. The Pearson correlation coefficient (r) for the Oncotype DX and average modified Magee recurrence scores was 0.6644 (n=283; Pscore>30 (n=8) or an average modified Magee recurrence scorescore, respectively. 86% (38/44) of cases with an average modified Magee recurrence score≤12, and 89% (34/38) of low grade tumors (NSscore. Using an algorithmic approach to eliminate high and low risk cases, between 5% and 23% of cases would potentially not have been sent by our institution for Oncotype DX testing, creating a potential cost savings between $56,550.00 and $282,750.00. The modified Magee recurrence score along with histologic criteria may be a cost-effective alternative to the Oncotype DX in risk stratifying certain breast cancer patients. The information needed is already generated by many pathology laboratories during the initial assessment of primary breast cancer, and the equations are free.

  11. Sliding-mode adaptive control of Pioneer 3-DX wheeled mobile robot

    Directory of Open Access Journals (Sweden)

    Adrian FILIPESCU

    2007-12-01

    Full Text Available Parameter identification scheme and discrete-time adaptive sliding-mode controller applied to Pioneer 3-DX wheeled mobile robot (WMR are presented in this paper. The dynamical model for mobile robot with one pair of active wheels, time–varying mass and moment of inertia have been used in sliding-mode control. Two closed-loop, on-line parameter estimators have been used in order to achieve robustness against parameter uncertainties (robot mass and moment of inertia. Two sliding-mode adaptive controllers corresponding to angular and position motion have been designed. Closed-loop circular trajectory tracking Pioneer 3-DX real-time control is presented.

  12. 枯草芽孢杆菌NJ-18的质粒消解及其在小麦根部的定殖%Plasmid Elimination of Bacillus subtilis NJ-18 and Its Colonization on Wheat Roots

    Institute of Scientific and Technical Information of China (English)

    卢靖乐; 余新燕; 侯毅平; 王建新; 周明国; 陈长军

    2013-01-01

    [目的]研究从土壤中分离出来的具有广谱抗菌活性的枯草芽孢杆菌(Bacillussubtilis)菌株NJ-18与作物互作关系,并观察外源导入绿色荧光蛋白(green fluorescent protein,GFP)基因的NJ-18菌株在小麦根部的定殖能力。[方法]首先使用十二烷基硫酸钠(SDS)消解NJ-18的质粒,然后采用化学法导入gfp分子标记,并采用激光共聚焦显微镜检测该标记菌株在小麦根部的定殖能力。[结果]获得了NJ-18的质粒消解菌株C136,并采用化学方法成功将外源基因导入野生型菌株NJ-18及其质粒消解菌株C136,C136的转化效率可达到3.42×105 cfu/μg质粒DNA,是NJ-18转化效率的10倍左右。对比NJ-18与C136的生物活性发现,C136能够保持原有的抑菌活性;但是C136的生长曲线第一峰值出现的时间滞后12 h,第一峰值被抑制了29.4%;NJ-18-GFP能够附着在病原菌菌体上,导致其菌丝呈现膨大、畸形等;接种7d后能够在小麦根部表皮和中柱稳定定殖。[结论]枯草芽孢杆菌NJ-18菌株的转化方法宜选用化学法;该菌株能够在小麦根部定殖。%[Objective]Bacillus subtilis strain NJ-18, isolated from the soil of oilseed rape field, has a broad spectrum antibacterial activity and a great potential for biocontrol. In order to study the interaction between NJ-18 and plants, NJ-18 was marked with a green fluorescent protein (gfp) gene and its colonization ability on wheat roots was observed with a laser scanning confocal microscope.[Method]The plasmids of NJ-18 were cured by sodium dodecyl sulfate (SDS) and gfp was transformed into the strain with a chemical method. Colonization ability of NJ-18 on wheat roots was observed with a laser scanning confocal microscope. [Result] By a chemical method, gfp was sucessfully transformed into wild strain NJ-18 and C136, a plasmid cured strain from NJ-18. The transformation efficiency of C136 could be up to 3.42×105 cfu/μg of

  13. Biodistribution Study of Intravenously Injected Cetuximab-IRDye700DX in Cynomolgus Macaques

    NARCIS (Netherlands)

    de Boer, E.; Samuel, S.; French, D. N.; Warram, J. M.; Schoeb, T. R.; Rosenthal, E. L.; Zinn, K. R.

    2016-01-01

    Purpose: The use of receptor-targeted antibodies conjugated to photosensitizers is actively being explored to enhance treatment efficacy. To facilitate clinical testing, we evaluated cetuximab conjugated to IRDye700DX (IR700) in cynomolgus macaques. Procedures: Total IR700 and intact cetuximab-IR700

  14. Optical and near-infrared observations of SN 2013dx associated with GRB 130702A

    CERN Document Server

    Toy, V L; Silverman, J M; Butler, N R; Cucchiara, A; Watson, A M; Bersier, D; Perley, D A; Margutti, R; Bellm, E; Bloom, J S; Cao, Y; Capone, J I; Clubb, K; Corsi, A; de Diego, J A; Filippenko, A V; Fox, O D; Gal-Yam, A; Gehrels, N; Georgiev, L; González, J J; Kasliwal, M M; Kelly, P L; Kulkarni, S R; Kutyrev, A S; Lee, W H; Prochaska, J X; Ramirez-Ruiz, E; Richer, M G; Román, C; Singer, L; Stern, D; Troja, E; Veilleux, S

    2015-01-01

    We present optical and near-infrared light curves and optical spectra of SN 2013dx, associated with the nearby (redshift 0.145) gamma-ray burst GRB 130702A. The prompt isotropic gamma-ray energy released from GRB 130702A is measured to be $E_{\\gamma,\\mathrm{iso}} = 6.4_{-1.0}^{+1.3} \\times 10^{50}$erg (1keV to 10MeV in the rest frame), placing it intermediate between low-luminosity GRBs like GRB 980425/SN 1998bw and the broader cosmological population. We compare the observed $g^{\\prime}r^{\\prime}i^{\\prime}z^{\\prime}$ light curves of SN 2013dx to a SN 1998bw template, finding that SN 2013dx evolves $\\sim20$% faster (steeper rise time), with a comparable peak luminosity. Spectroscopically, SN 2013dx resembles other broad-lined Type Ic supernovae, both associated with (SN 2006aj and SN 1998bw) and lacking (SN 1997ef, SN 2007I, and SN 2010ah) gamma-ray emission, with photospheric velocities around peak of $\\sim$21,000 km s$^{-1}$. We construct a quasi-bolometric ($g^{\\prime}r^{\\prime}i^{\\prime}z^{\\prime}yJH$) li...

  15. Treatment Choices Based on OncotypeDx in the Breast Oncology Care Setting

    Directory of Open Access Journals (Sweden)

    Teri L. Malo

    2012-01-01

    Full Text Available Introduction. This study aimed to evaluate whether OncotypeDx test results predict receipt of adjuvant chemotherapy in breast cancer patients who received an OncotypeDx recurrence score (RS. Materials and Methods. Pathology records were used to identify breast cancer patients who had OncotypeDx testing between December 2004 and January 2009 (n=118. Patient sociodemographic information, tumor characteristics, RS, and treatment-specific data were collected via chart review. RS was classified as follows: low (RS≤17, intermediate (RS = 18–30, or high (RS≥31. Bivariate analyses were conducted to investigate the relationship between adjuvant chemotherapy receipt and each sociodemographic and clinical characteristic; significant sociodemographic and clinical variables were included in a multivariable logistic regression model. Results. In multivariable analysis controlling for tumor size, histologic grade, and nuclear grade, only RS remained significantly associated with chemotherapy uptake. Relative to low RS, an intermediate (adjusted odds ratio [AOR], 21.24; 95% confidence interval [CI], 3.62–237.52 or high (AOR, 15.07; 95% CI, 1.28–288.21 RS was associated with a greater odds of chemotherapy uptake. Discussion. Results indicate that RS was significantly associated with adjuvant chemotherapy uptake, suggesting that OncotypeDx results were used to inform treatment decision making, although it is unclear if and how the information was conveyed to patients.

  16. Kindle DX

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    让人有点惊讶的是,Kindle DX除了屏幕比较大以外。居然跟Kindle 2一模一样。在我试用Kindle DX的短暂时间里,得到的大部分印象都是好的,正如广告所言,屏幕变大后要阅读报纸或杂志变得较方便,特别是有照片或图片时。单一页面可读到的文字变多了,感觉上更像是阅读真的报纸。

  17. 33 CFR 334.100 - Atlantic Ocean off Cape May, N.J.; Coast Guard Rifle Range.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Atlantic Ocean off Cape May, N.J.; Coast Guard Rifle Range. 334.100 Section 334.100 Navigation and Navigable Waters CORPS OF ENGINEERS... Ocean off Cape May, N.J.; Coast Guard Rifle Range. (a) The danger zone. The waters of the Atlantic...

  18. 76 FR 11679 - Drawbridge Operation Regulation; Shark River (South Channel), Belmar, NJ

    Science.gov (United States)

    2011-03-03

    ... SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulation; Shark River (South Channel), Belmar... operation of the S71 Bridge across Shark River (South Channel), mile 0.8, at Belmar, NJ. The deviation is... INFORMATION: The S71 Bridge, a bascule lift drawbridge, across Shark River (South Channel), at mile 0.8,...

  19. 77 FR 70372 - Drawbridge Operation Regulation; Shark River (South Channel), Avon Township, NJ

    Science.gov (United States)

    2012-11-26

    ... SECURITY Coast Guard 33 CFR Part 117 RIN 1625-AA09 Drawbridge Operation Regulation; Shark River (South..., across Shark River (South Channel) at Avon Township, NJ. The existing regulation contains a drawbridge... Transportation (NJDOT) to replace the existing bascule bridge, which carries S35 over Shark River (South...

  20. 33 CFR 162.30 - Channel of Tuckerton Creek, N.J.; navigation.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Channel of Tuckerton Creek, N.J.; navigation. 162.30 Section 162.30 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY INLAND WATERWAYS NAVIGATION REGULATIONS § 162.30 Channel...

  1. 77 FR 14690 - Drawbridge Operation Regulation; New Jersey Intracoastal Waterway (NJICW), Point Pleasant Canal, NJ

    Science.gov (United States)

    2012-03-13

    ...The Commander, Fifth Coast Guard District, has issued a temporary deviation from the regulations governing the operation of the Route 88/Veterans Memorial Bridge across Point Pleasant Canal, NJICW mile 3.0, at Point Pleasant, NJ. This deviation allows the bridge to remain closed-to-navigation in order to facilitate barrier gate replacement and extensive electrical remedial work on the...

  2. 78 FR 21849 - Television Broadcasting Services; Ely, NV to Middletown Township, NJ

    Science.gov (United States)

    2013-04-12

    ... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 Television Broadcasting Services; Ely, NV to Middletown Township, NJ AGENCY... U.S.C. 801(a)(1)(A). List of Subjects in 47 CFR Part 73 Television. Federal...

  3. 77 FR 27115 - Drawbridge Operation Regulations; Raritan River, Perth Amboy, NJ

    Science.gov (United States)

    2012-05-09

    ... SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Raritan River, Perth Amboy, NJ... Perth Amboy, New Jersey. Under this temporary deviation the draw may remain in the closed position for..., mile 0.5, at Perth Amboy, New Jersey, has a vertical clearance in the closed position of 8 feet at...

  4. The Oil Game: Generating Enthusiasm for Geosciences in Urban Youth in Newark, NJ

    Science.gov (United States)

    Gates, Alexander E.; Kalczynski, Michael J.

    2016-01-01

    A hands-on game based upon principles of oil accumulation and drilling was highly effective at generating enthusiasm toward the geosciences in urban youth from underrepresented minority groups in Newark, NJ. Participating 9th-grade high school students showed little interest in the geosciences prior to participating in the oil game, even if they…

  5. 77 FR 46613 - Safety Zone; 2012 Ironman US Championship Swim, Hudson River, Fort Lee, NJ

    Science.gov (United States)

    2012-08-06

    ...) entitled 2012 Ironman US Championship Swim, Hudson River, Fort Lee, NJ in the Federal Register (77 FR 34285...) 366-9826. SUPPLEMENTARY INFORMATION: Table of Acronyms DHS Department of Homeland Security FR Federal... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; 2012 Ironman US Championship Swim,...

  6. Managing a Statewide Virtual Reference Service: How Q and A NJ Works.

    Science.gov (United States)

    Bromberg, Peter

    2003-01-01

    Describes the live virtual reference service, Q and A NJ (Question and Answer New Jersey), strategies used to meet the challenges of day-to-day management, scaled growth and quality control. Describes how it began; how long it took; how to manage a large project (constant communication; training and practice; transcript analysis and privacy;…

  7. Near-degeneracy of extended s +dx2-y2 and dx y order parameters in quasi-two-dimensional organic superconductors

    Science.gov (United States)

    Guterding, Daniel; Altmeyer, Michaela; Jeschke, Harald O.; Valentí, Roser

    2016-07-01

    The symmetry of the superconducting order parameter in quasi-two-dimensional bis-ethylenedithio-tetrathiafulvalene (BEDT-TTF) organic superconductors is a subject of ongoing debate. We report ab initio density-functional-theory calculations for a number of organic superconductors containing κ -type layers. Using projective Wannier functions, we derive the parameters of a common low-energy Hamiltonian based on individual BEDT-TTF molecular orbitals. In a random-phase approximation spin-fluctuation approach, we investigate the evolution of the superconducting pairing symmetry within this model, and we point out a phase transition between extended s +dx2-y2 and dx y symmetry. We discuss the origin of the mixed order parameter and the relation between the realistic molecule description and the widely used dimer approximation. Based on our ab initio calculations, we position the investigated materials in the obtained molecule model phase diagram, and we simulate scanning tunneling spectroscopy experiments for selected cases. Our calculations show that many κ -type materials lie close to the phase-transition line between the two pairing symmetry types found in our calculation, possibly explaining the multitude of contradictory experiments in this field.

  8. Simulation of control circuit of servo mechanism with DxAnalog%用DxAnalog进行某型伺服机构控制电路的仿真

    Institute of Scientific and Technical Information of China (English)

    张世欣; 郑维斌

    2012-01-01

    为了能更好地理解某型伺服机构控制电路原理并确定参数,采用Mentor公司的DxAnalog软件对电路进行了详尽的仿真分析.通过改变参数,观察不同电路参数对电路性能的影响,实时的观察各实验点的仿真波形并精确测量出量值的变化,极大地缩减了电路调试过程,提高了设计效率.%In order to have a good knowledge of the control circuit principles of a servo mechanism and determine the parameters, the circuit is simulated and analyzed with DxAnalog software of Metor Company. The effect of variable circuit parameters on circuit performance was observed. Through a real-time observation of the simulation waveform at the experimental points and accurate measurement of the variables, the debugging process of the circuit was greatly reduced and the design efficiency was improved.

  9. A transition radiation detector for RHIC featuring accurate tracking and dE/dx particle identification

    Energy Technology Data Exchange (ETDEWEB)

    O`Brien, E.; Lissauer, D.; McCorkle, S.; Polychronakos, V.; Takai, H. [Brookhaven National Lab., Upton, NY (United States); Chi, C.Y.; Nagamiya, S.; Sippach, W.; Toy, M.; Wang, D.; Wang, Y.F.; Wiggins, C.; Willis, W. [Columbia Univ., New York, NY (United States); Cherniatin, V.; Dolgoshein, B. [Moscow Institute of Physics and Engineering, (Russian Federation); Bennett, M.; Chikanian, A.; Kumar, S.; Mitchell, J.T.; Pope, K. [Yale Univ., New Haven, CT (United States)

    1991-12-31

    We describe the results of a test ran involving a Transition Radiation Detector that can both distinguish electrons from pions which momenta greater titan 0.7 GeV/c and simultaneously track particles passing through the detector. The particle identification is accomplished through a combination of the detection of Transition Radiation from the electron and the differences in electron and pion energy loss (dE/dx) in the detector. The dE/dx particle separation is most, efficient below 2 GeV/c while particle ID utilizing Transition Radiation effective above 1.5 GeV/c. Combined, the electron-pion separation is-better than 5 {times} 10{sup 2}. The single-wire, track-position resolution for the TRD is {approximately}230 {mu}m.

  10. A transition radiation detector which features accurate tracking and dE/dx particle identification

    Energy Technology Data Exchange (ETDEWEB)

    O`Brien, E.; Lissauer, D.; McCorkle, S.; Polychronakos, V.; Takai, H. [Brookhaven National Lab., Upton, NY (United States); Chi, C.Y.; Nagamiya, S.; Sippach, W.; Toy, M.; Wang, D.; Wang, Y.F.; Wiggins, C.; Willis, W. [Columbia Univ., New York, NY (United States); Cherniatin, V.; Dolgoshein, B. [Moscow Inst. of Physics and Engineering, Moscow (Russia Federation); Bennett, M.; Chikanian, A.; Kumar, S.; Mitchell, J.T.; Pope, K. [Yale Univ., New Haven, CT (United States)

    1991-12-31

    We describe the results of a test run involving a Transition Radiation Detector that can both distinguish electrons from pions with momenta greater than 0.7 GeV/c and simultaneously track particles passing through the detector. The particle identification is accomplished through a combination of the detection of Transition Radiation from the electron and the differences in electron and pion energy loss (dE/dx) in the detector. The dE/dx particle separation is most efficient below 2 GeV/c while particle ID utilizing Transition Radiation is effective above 1.5 GeV/c. Combined, the electron-pion separation is better than 5 {times} l0{sup 2}. The single-wire, track-position resolution for the TRD is {approximately}230{mu}m.

  11. A transition radiation detector which features accurate tracking and dE/dx particle identification

    Energy Technology Data Exchange (ETDEWEB)

    O' Brien, E.; Lissauer, D.; McCorkle, S.; Polychronakos, V.; Takai, H. (Brookhaven National Lab., Upton, NY (United States)); Chi, C.Y.; Nagamiya, S.; Sippach, W.; Toy, M.; Wang, D.; Wang, Y.F.; Wiggins, C.; Willis, W. (Columbia Univ., New York, NY (United States)); Cherniatin, V.; Dolgoshein, B. (Moscow Inst. of Physics and Engineering (Russian Federation)); Bennett, M.; Chikanian, A.; Kumar, S.; Mitchell, J.T.; Pope, K. (Yale Univ., New Haven, CT (United States))

    1993-04-01

    The authors describe the results of a test run involving a Transition Radiation Detector that can both distinguish electrons from pions with momenta greater than 0.7 GeV/c and simultaneously track particles passing through the detector. The particle identification is accomplished through a combination of the detection of Transition Radiation from the electron and the differences in electron and pion energy loss (dE/dx) in the detector. The dE/dx particle separation is most efficient below 2 GeV/c while particle ID utilizing Transition Radiation is effective above 1.5 GeV/c. Combined, the electron-pion separation is better than 5 x 10[sup 2]. The single-wire, track-position resolution for the TRD is [approximately] [mu]m.

  12. Test report for single event effects of the 80386DX microprocessor

    Science.gov (United States)

    Watson, R. Kevin; Schwartz, Harvey R.; Nichols, Donald K.

    1993-01-01

    The Jet Propulsion Laboratory Section 514 Single Event Effects (SEE) Testing and Analysis Group has performed a series of SEE tests of certain strategic registers of Intel's 80386DX CHMOS 4 microprocessor. Following a summary of the test techniques and hardware used to gather the data, we present the SEE heavy ion and proton test results. We also describe the registers tested, along with a system impact analysis should these registers experience a single event upset.

  13. Comparison of hadronic shower punchthrough and TeV muon dE/dx with calculation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, B.J.; De Barbaro, P.; Bodek, A.; Budd, H.S.; Sakumoto, W.K. (Rochester Univ., NY (USA)); Merritt, F.S.; Oreglia, M.J.; Schellman, H.; Schumm, B.A. (Chicago Univ., IL (USA)); Arroyo, C.; Bachmann, K.T.; Blair, R.E.; Foudas, C.; King, B.; Lefmann, W.C.; Leung, W.C.; Mishra, S.R.; Oltman, E.; Quintas, P.Z.; Rabinowitz, S.A.; Sciulli, F.; Seligman, W.G.; Shaevitz, M.H. (Columbia Univ., NY (USA)); Bernstein, R.H.; Borcherding, F.O.; Fisk, H.E.; Lamm, M.J.; Marsh, W.; Merritt, K.W.; Rapidis, P.A.; Yovanovitch, D. (Fermi National Accelerator Lab., Batavia, IL (USA)); Sandler, P.H.; Smith, W.H. (Wisconsin Univ., Madison, WI (USA))

    1991-07-01

    We have measured the longitudinal particle punchthrough probability from shower cascades produced by hadrons incident on the iron-scintillator calorimeter of the CCFR neutrino detector and have compared them to a Monte Carlo simulation. Measurements of the dE/dx energy loss in iron of high energy cosmic ray muons (up to 1 TeV) incident on the same detector are presented and are compared against calculation. (orig.).

  14. The clinical observation of neoadjuvant chemotherapy in locally advanced breast cancer with DX regimen

    Institute of Scientific and Technical Information of China (English)

    Miao Zhang; Jianing Qiu; Shuxian Qu; Yaling Han; Zhaozhe Liu; Xiaodong Xie

    2014-01-01

    Objective:The recent clinical curative ef ect and adverse events of docetaxel and capecitabine (DX) of neo-adjuvant chemotherapy in patients with local y advanced breast cancer was discussed. Methods:The data of 72 cases of neoadjuvant chemotherapy (DX) in local y advanced breast cancer after 4 cycles were retrospectively analyzed. Docetaxel 75 mg/m2 by infusion 1 h on d1, capecitabine 2000 mg/m2 by oral for twice daily on d1–14, 21 days was a cycle. Results:Al 72 patients were assessed for ef icacy and adverse events. The total ef ective rate was 80.5%(58/72), including pathological complete response (pCR) was 7 (9.7%), clinical complete remission (cCR) was 15(20.8%), clinical partial response (PR) was 43 (59.7%), stable disease (SD) was 8 (11.1%) and progressive disease (PD) was 6 (8.3%). The main adverse events were gastrointestinal reactions and bone marrow suppression. The 3 to 4 degrees of adverse reactions including granulocytopenia in 7 patients (20.6%), hand-foot syndrome in 6 patients (15.2%). Conclusion:The DX regimen provide a favorable ef icacy and safety profile in patients with local y advanced breast cancer for neoadjuvant chemotherapy.

  15. In vivo binding, pharmacokinetics and metabolism of the selective M{sub 2} muscarinic antagonists [{sup 3}H]AF-DX 116 and [{sup 3}H]AF-DX 384 in the anesthetized rat

    Energy Technology Data Exchange (ETDEWEB)

    Mickala, Patrick; Boutin, Herve; Bellanger, Cecile; Chevalier, Cyril; MacKenzie, Eric T.; Dauphin, Francois

    1996-02-01

    The pharmacokinetics, in vivo binding and metabolism of two M{sub 2} muscarinic receptor antagonists, [{sup 3}H]AF-DX 116 and [{sup 3}H]AF-DX 384, were studied in anesthetized rats, which received either the tracer alone or following a saturating injection of atropine. Both radioligands were cleared from the circulation with distribution half-lives of 17 and 14 sec and elimination half-lives of 17 and 40 min for [{sup 3}H]AF-DX 116 and [{sup 3}H]AF-DX 384, respectively. A radioactive distribution, predominant in peripheral organs when compared to brain, was found at each time studied after tracer injection. Atropine-displaceable tracer uptake was evidenced at 20-40 min in brain (31%), submandibular glands (26%), spleen (37%) and notably heart (55%) for [{sup 3}H]AF-DX 116 but only in heart (50%) for [{sup 3}H]AF-DX 384 at 10-20 min. Regional brain sampling revealed a relatively uniform distribution of [{sup 3}H]AF-DX 384 and a -45% atropine saturation effect (i.e., specific binding) in the thalamus 20 min after injection. Sequential thin-layer chromatographic studies performed on tissue extracts demonstrated the rapid appearance of labeled metabolites of both radiotracers in brain (but less so in liver) and especially in cardiac tissues, where almost 70% of total radioactivity still corresponded to authentic tracer 40 min after injection. Thus, based on their low blood-brain barrier permeability and the high presence of labeled metabolites in the central nervous system, AF-DX 116 and AF-DX 384 might be more helpful in the study of M{sub 2} muscarinic receptors present in heart rather than brain. Labeled with positron emittors, these M{sub 2} antagonists might be applicable to the pathophysiological study of disease states, such as cardiomyopathies.

  16. The Single Event Effect Characteristics of the 486-DX4 Microprocessor

    Science.gov (United States)

    Kouba, Coy; Choi, Gwan

    1996-01-01

    This research describes the development of an experimental radiation testing environment to investigate the single event effect (SEE) susceptibility of the 486-DX4 microprocessor. SEE effects are caused by radiation particles that disrupt the logic state of an operating semiconductor, and include single event upsets (SEU) and single event latchup (SEL). The relevance of this work can be applied directly to digital devices that are used in spaceflight computer systems. The 486-DX4 is a powerful commercial microprocessor that is currently under consideration for use in several spaceflight systems. As part of its selection process, it must be rigorously tested to determine its overall reliability in the space environment, including its radiation susceptibility. The goal of this research is to experimentally test and characterize the single event effects of the 486-DX4 microprocessor using a cyclotron facility as the fault-injection source. The test philosophy is to focus on the "operational susceptibility," by executing real software and monitoring for errors while the device is under irradiation. This research encompasses both experimental and analytical techniques, and yields a characterization of the 486-DX4's behavior for different operating modes. Additionally, the test methodology can accommodate a wide range of digital devices, such as microprocessors, microcontrollers, ASICS, and memory modules, for future testing. The goals were achieved by testing with three heavy-ion species to provide different linear energy transfer rates, and a total of six microprocessor parts were tested from two different vendors. A consistent set of error modes were identified that indicate the manner in which the errors were detected in the processor. The upset cross-section curves were calculated for each error mode, and the SEU threshold and saturation levels were identified for each processor. Results show a distinct difference in the upset rate for different configurations of

  17. Asymptotics of Wigner 3nj-symbols with Small and Large Angular Momenta: an Elementary Method

    CERN Document Server

    Bonzom, Valentin

    2011-01-01

    Yu and Littlejohn recently studied in arXiv:1104.1499 some asymptotics of Wigner symbols with some small and large angular momenta. They found that in this regime the essential information is captured by the geometry of a tetrahedron, and gave new formulae for 9j, 12j and 15j-symbols. We present here an alternative derivation which leads to a simpler formula, based on the use of the Ponzano-Regge formula for the relevant tetrahedron. The approach is generalized to Wigner 3nj-symbols with some large and small angular momenta, where more than one tetrahedron is needed, leading to new asymptotics for Wigner 3nj-symbols. As an illustration, we present 15j-symbols with one, two and four small angular momenta, and give an alternative formula to Yu's recent 15j-symbol with three small spins.

  18. The dE/dx capabilities of the D0 tracking system

    Energy Technology Data Exchange (ETDEWEB)

    Rajagopalan, Srinivasan [Northwestern Univ., Evanston, IL (United States)

    1992-06-01

    The D0 forward tracking system has been extensively calibrated using electron and pion beams in the energy range from 10 GeV to 150 GeV in the neutrino area fixed target beam line at Fermilab. The forward tracking system provides a spatial resolution of 200 μm and a two hit separation of 2.5 mm at 90% efficiency. The chamber provides 32 samples of pulse height information for a given track equivalent to a dE/dx resolution of 12.7%. The energy loss response of the chamber to low energy-beam has been studied. A Monte Carlo simulation program has been developed based on the Photo Absorption Ionization model to simulate the dE/dx response of the chamber. The observations made using low energy test beam are consistent with the model`s predictions. The dE/dx measurement in the D0 tracking system provides identification of electrons against gamma conversions resulting from π0 decays. The rejection factor of distinguishing doubly minimum ionizing tracks in the chamber has been measured to be 30.5 with the requirement that singly minimum ionizing tracks be identified with a 90% efficiency. This factor improves with lower multiplicity. Using a Monte Carlo program based on GEANT, the identification efficiency of electrons and π0`s has been determined. Using the capabilities of the outer tracking system alone, the background due to isolated π0 production is reduced by up to a factor of 60 in the central direction based on measurements made on a sample of simulated QCD two jet events.

  19. Antistaphylococcal activity of DX-619 alone and in combination with vancomycin, teicoplanin, and linezolid assessed by time-kill synergy testing.

    Science.gov (United States)

    Credito, Kim; Lin, Genrong; Appelbaum, Peter C

    2007-04-01

    Time-kill synergy studies testing in vitro activity of DX-619 alone and with added vancomycin, teicoplanin, or linezolid against 101 Staphylococcus aureus strains showed synergy between DX-619 and teicoplanin at 12 to 24 h in 72 strains and between DX-619 and vancomycin in 28 strains. No synergy was found with linezolid, and no antagonism was observed with any combination.

  20. The Beckman DxI 800 prolactin assay demonstrates superior specificity for monomeric prolactin.

    LENUS (Irish Health Repository)

    Byrne, Brendan

    2010-02-01

    Commercially available prolactin immunoassays detect macroprolactin to variable degrees. Best practice requires laboratories to assess the cross-reactivity of their prolactin assay with macroprolactin, and where appropriate, introduce a screen for the presence of macroprolactin. Our policy has been to reanalyse hyperprolactinaemic samples following polyethylene glycol (PEG) precipitation and to report the resultant value as the monomeric prolactin content of the sample. The goal of this study was to determine the need to continue PEG precipitation when prolactin measurements with the Wallac AutoDELFIA were replaced by the Beckman DxI 800.

  1. Antistaphylococcal activity of DX-619, a new des-F(6)-quinolone, compared to those of other agents.

    Science.gov (United States)

    Bogdanovich, Tatiana; Esel, Duygu; Kelly, Linda M; Bozdogan, Bülent; Credito, Kim; Lin, Gengrong; Smith, Kathy; Ednie, Lois M; Hoellman, Dianne B; Appelbaum, Peter C

    2005-08-01

    The in vitro activity of DX-619, a new des-F(6)-quinolone, was tested against staphylococci and compared to those of other antimicrobials. DX-619 had the lowest MIC ranges/MIC(50)s/MIC(90)s (microg/ml) against 131 Staphylococcus aureus strains (32), and ciprofloxacin (>32/>32). Raised quinolone MICs were associated with mutations in GyrA (S84L) and single or double mutations in GrlA (S80F or Y; E84K, G, or V) in all S. aureus strains tested. A recent vancomycin-resistant S. aureus (VRSA) strain (Hershey) was resistant to available quinolones and was inhibited by DX-619 at 0.25 microg/ml and sitafloxacin at 1.0 microg/ml. Vancomycin (except VRSA), linezolid, ranbezolid, tigecycline, and quinupristin-dalfopristin were active against all strains, and teicoplanin was active against S. aureus but less active against coagulase-negative staphylococci. DX-619 produced resistant mutants with MICs of 1 to >32 microg/ml after 32 microg/ml for ciprofloxacin, sitafloxacin, moxifloxacin, and gatifloxacin. DX-619 and sitafloxacin were also more active than other tested drugs against selected mutants and had the lowest mutation frequencies in single-step resistance selection. DX-619 and sitafloxacin were bactericidal against six quinolone-resistant (including the VRSA) and seven quinolone-susceptible strains tested, whereas gatifloxacin, moxifloxacin, levofloxacin, and ciprofloxacin were bactericidal against 11, 10, 7, and 5 strains at 4x MIC after 24 h, respectively. DX-619 was also bactericidal against one other VRSA strain, five vancomycin-intermediate S. aureus strains, and four vancomycin-intermediate coagulase-negative staphylococci. Linezolid, ranbezolid, and tigecycline were bacteriostatic and quinupristin-dalfopristin, teicoplanin, and vancomycin were bactericidal against two, eight, and nine strains, and daptomycin and oritavancin were rapidly bactericidal against all strains, including the VRSA. DX-619 has potent in vitro activity against staphylococci, including

  2. Role of N-terminal domain of HMW 1Dx5 in the functional and structural properties of wheat dough.

    Science.gov (United States)

    Wang, Jing Jing; Liu, Guang; Huang, Yan-Bo; Zeng, Qiao-Hui; Song, Guo-Sheng; Hou, Yi; Li, Lin; Hu, Song-Qing

    2016-12-15

    Effects of N-terminal domain of high molecular weight glutenin subunit (HMW-GS) 1Dx5 (1Dx5-N) on functional and structural properties of wheat dough were determined by farinographic and rheological analysis, size exclusion chromatography, non-reducing/reducing SDS-PAGE, total free sulfhydryl determination, scanning electron microscopy and Fourier transform infrared spectroscopy. Results showed that 1Dx5-N improved the quality of dough with the increased water absorption, dough stability time, elastic and viscous modulus, and the decreased degree of softening, loss tangent. These improvements could be attributed to the formation of the macro-molecular weight aggregates and massive protein networks, which were favored by 1Dx5-N through disulfide bonds and hydrophobic interactions. Additionally, 1Dx5-N drove the transition of α-helix and random coil conformations to β-sheet and β-turn conformations, further demonstrating the formation of HMW-GS polymers and the enhancement of dough strength. Moreover, all the positive effects of 1Dx5-N were reinforced by edible salt NaCl.

  3. Critical need for MFE: the Alcator DX advanced divertor test facility

    Science.gov (United States)

    Vieira, R.; Labombard, B.; Marmar, E.; Irby, J.; Wolf, S.; Bonoli, P.; Fiore, C.; Granetz, R.; Greenwald, M.; Hutchinson, I.; Hubbard, A.; Hughes, J.; Lin, Y.; Lipschultz, B.; Parker, R.; Porkolab, M.; Reinke, M.; Rice, J.; Shiraiwa, S.; Terry, J.; Theiler, C.; Wallace, G.; White, A.; Whyte, D.; Wukitch, S.

    2013-10-01

    Three critical challenges must be met before a steady-state, power-producing fusion reactor can be realized: how to (1) safely handle extreme plasma exhaust power, (2) completely suppress material erosion at divertor targets and (3) do this while maintaining a burning plasma core. Advanced divertors such as ``Super X'' and ``X-point target'' may allow a fully detached, low temperature plasma to be produced in the divertor while maintaining a hot boundary layer around a clean plasma core - a potential game-changer for magnetic fusion. No facility currently exists to test these ideas at the required parallel heat flux densities. Alcator DX will be a national facility, employing the high magnetic field technology of Alcator combined with high-power ICRH and LHCD to test advanced divertor concepts at FNSF/DEMO power exhaust densities and plasma pressures. Its extended vacuum vessel contains divertor cassettes with poloidal field coils for conventional, snowflake, super-X and X-point target geometries. Divertor and core plasma performance will be explored in regimes inaccessible in conventional devices. Reactor relevant ICRF and LH drivers will be developed, utilizing high-field side launch platforms for low PMI. Alcator DX will inform the conceptual development and accelerate the readiness-for-deployment of next-step fusion facilities.

  4. AA6082 to DX56-Steel Laser Brazing: Process Parameter-Intermetallic Formation Correlation

    Science.gov (United States)

    Narsimhachary, D.; Pal, S.; Shariff, S. M.; Padmanabham, G.; Basu, A.

    2017-09-01

    In the present study, laser-brazed AA6082 to DX56-galvanized steel joints were investigated to understand the influence of process parameters on joint strength in terms of intermetallic layer formation. 1.5-mm-thick sheet of aluminum alloy (AA6082-T6) and galvanized steel (DX56) sheet of 0.7 mm thickness were laser-brazed with 1.5-mm-diameter Al-12% Si solid filler wire. During laser brazing, laser power (4.6 kW) and wire feed rate (3.4 m/min) were kept constant with a varying laser scan speed of 3.5, 3, 2.5, 2, 1.5, and 1 m/min. Microstructure of brazed joint reveals epitaxial growth at the aluminum side and intermetallic layer formation at steel interface. Intermetallic layer formation was confirmed by EDS analysis and XRD study. Hardness profile showed hardness drop in filler region, and failure during tensile testing was initiated through the filler region near the steel interface. As per both experimental study and numerical analysis, it was observed that intermetallic layer thickness decreases with increasing brazing speed. Zn vaporization from galvanized steel interface also affected the joint strength. It was found that high laser scan speed or faster cooling rate can be chosen for suppressing intermetallic layer formation or at least decreasing the layer thickness which results in improved mechanical properties.

  5. A four-year experience with patient individualized heparin and protamine dosing using the Hemochron RxDx system.

    Science.gov (United States)

    Bennett, K M; Briggins, D; Zucker, M; LaDuca, F

    2001-02-01

    Cardiac surgical case histories, collected over 4 years at Huntsville Hospital in Alabama, were reviewed for 2,293 patients. Patients were separated into two dosing groups for both heparin and protamine, hospital empirically dosed and Hemochron RxDx dosed. Review of the heparin dosing information found that incomplete data were collected for 47 patients, leaving 2,246 patients eligible to be evaluated for heparin dose comparison. Both RxDx recommended and empirically calculated doses were recorded, as well as the actual dose given. Of the 2,246 patients, 1671 were administered heparin according to the RxDx calculated dose, and the remaining 575 patients were dosed according to the hospital's empirical protocol. The average RxDx calculated heparin dose was 17% greater then the empirically calculated heparin dose (350 U/kg) (p RxDx recommended dose; whereas, in the empirically dosed patient group only 80% of the patients reached the target ACT after initial heparin bolus dose. Incomplete protamine dosing data was recorded for 336 patients, leaving a total of 1,957 patients available for protamine dose evaluation. All patients had an RxDx protamine calculation, empirical protamine calculation, and actual amount of protamine dosed recorded. Of the 1,953 patients, 1,764 were dosed according to the RxDx recommended dose, with the remaining 189 patients dosed empirically (1 mg protamine/100 U of heparin). In both the RxDx and the empirical groups, 96% of the patients returned to baseline following initial protamine infusion. The overall RxDx dose (293 mg) was 16% lower than the average empirical dose (348 mg). The RxDx system has been shown to be an effective method for determining patient-specific dosing for both heparin and protamine. This long-term clinical experience demonstrates the consistency and reliability of patient maintenance using this individualized dosing system, which has been shown, in other independent evaluations, to lead to improved patient outcomes.

  6. Impact of Oncotype DX on treatment decisions in ER-positive, node-negative breast cancer with histologic correlation.

    Science.gov (United States)

    Biroschak, Julianne R; Schwartz, Gordon F; Palazzo, Juan P; Toll, Adam D; Brill, Kristin L; Jaslow, Rebecca J; Lee, Sun Yong

    2013-01-01

    Oncotype DX, a gene-expression profiling assay, provides stratification of patients with estrogen-receptor positive, lymph-node-negative early breast cancer into risk groups based on recurrence score, which are associated with distant recurrence and response to chemotherapy. This study aims to determine whether Oncotype DX influences clinicians' treatment decisions, and whether assay results correlate with histologic assessment. Fifty patients with estrogen-receptor positive, node-negative early breast cancer analyzed by Oncotype DX and operated on by two breast surgeons were included. To assess effect on treatment decisions, clinical vignettes were created by retrospective chart review. Physicians were then presented with the clinical vignettes and instructed to make a treatment decisions (i.e., hormone therapy alone versus hormone therapy combined with chemotherapy) both before and after knowledge of the recurrence score. To assess correlation with histologic assessment, a prospective, blinded review of tumor slides was performed by two pathologists. Based on this review, tumors were placed into low, intermediate and high risk groups for comparison with Oncotype DX assay results. Treatment decisions were changed based on Oncotype DX results in 36 and 18% of cases by breast surgeons and medical oncologists, respectively. All tumors categorized as high risk by Oncotype DX were categorized as high risk based on histologic assessment, and 96% of cases categorized as low risk by recurrence score were categorized as low or intermediate risk by histologic assessment. Oncotype DX significantly influences management of estrogen-receptor positive, lymph-node-negative early breast cancer. Further studies are needed to assess association of histologic categorization to assay results. © 2013 Wiley Periodicals, Inc.

  7. Initial performance evaluation of the UniCel® DxH 800 Coulter® cellular analysis system.

    Science.gov (United States)

    Hedley, B D; Keeney, M; Chin-Yee, I; Brown, W

    2011-02-01

    The Beckman Coulter UniCel® DxH 800 is a hematology analyzer incorporating new electronic and mechanical design with advanced algorithm technology to perform CBC, white blood cell (WBC) differential, nucleated red blood cell (NRBC), and reticulocyte analysis. Evaluation of this instrument was performed in our 800-bed tertiary care hospital and specifically centered upon the correlation of WBC, NRBC, and platelet (PLT) enumeration when compared to a predicate analyzer, the Coulter® LH 780, and flow cytometry (FCM) reference methods. Of particular interest were those samples with morphologically confirmed interference and extreme leukocytosis (evaluated with respect to red blood cell parameter correction). The sample set (n=272) consisted of morphologically normal and hematologically abnormal patients. Correlation of the WBC, PLT, and NRBC showed r(2) values of 0.994, 0.985, and 0.910 for the DxH 800 vs. FCM, respectively. The presence of interfering particles did not affect the accuracy of the DxH 800 with respect to WBC counts. The DxH 800 showed accurate PLT and NRBC counts in the clinically significant low range when compared to FCM. Compared to the LH 780, flagging rates were significantly reduced (NRBC flag), or equivalent (WBC, PLT flag) on the DxH 800. The DxH 800 demonstrated higher sensitivity and specificity for PLTs and NRBCs and achieved a lower NRBC false negative rate compared to the LH 780. The UniCel® DxH 800 represents a significant improvement to previous impedance analyzers in accurately detecting the presence of NRBCs at counts >1/100 WBC. Furthermore, it provides accurate PLT and WBC counts in the presence of interference and improved NRBC flagging efficiency when compared to the LH 780. Correction of red blood cell parameters is appropriate and accurate in cases of extreme leukocytosis.

  8. Normal dispersion erbium-doped fiber laser with pulse energies above 10 nJ.

    Science.gov (United States)

    Ruehl, Axel; Kuhn, Vincent; Wandt, Dieter; Kracht, Dietmar

    2008-03-03

    We report on an erbium-doped fiber oscillator mode-locked by nonlinear polarization evolution operating in the large normal dispersion regime. The setup produced highly chirped 10 nJ pulses at 37 MHz which can be compressed externally to below 75 fs. Hence, this simple and practical setup is capable of providing ultrashort pulses with a peak power of 140 kW. The pulse formation is indeed subject to intrapulse Raman-scattering but a clean and stable pulse train can be observed. The similarities as well as the differences of the output characteristics to the parabolic pulse and wave breaking-free regime are explicated.

  9. Direct measurement of DX-centre related lattice relaxations in Al$_{x}$Ga$_{1-x}$As compounds

    CERN Multimedia

    2002-01-01

    Donor impurities from elements of group IV and VI form localized electronic states, so-called DX-centers, in AlGaAs and other semiconductors. One of the well known effects related to DX-centers is the persistent photoconductivity. In spite of extensive studies, the microscopic structure of the DX-center is still a matter of controversy. The direct determination of the donor lattice sites and their microscopical surrounding is a crucial point in understanding the relation of microscopic structure to the localized electronic state of the DX-center.\\\\ It is proposed to implant radioactive group VI elements $^{73}$Se (from $^{73}$Br) and $^{118}$Te (from $^{118}$Xe) into Al$_{x}$Ga$_{1-x}$As of different mole fractions ${x}$ and to determine (i) the lattice site of Te and Se impurities by emission channeling of decay positrons and electrons (ii) the local structure of Se impurities using the perturbed $\\gamma$-$\\gamma$-angular correlation technique (PAC). The appearance of the DX-center shall be check...

  10. Tracking in dense environments and its inefficiency measurement using pixel $dE/dx$

    CERN Document Server

    Mansour, Jason Dhia; The ATLAS collaboration

    2016-01-01

    We present a measurement of the charged particle reconstruction inefficiency inside of jet cores, using data collected by the ATLAS experiment in 2015 of $pp$ collisions produced at the LHC, at a center of mass energy of 13 TeV. The determination of this inefficiency is important for jet energy scale and mass calibration, as well as multiple other performance studies and analyses. A data driven method is used, where the fraction of lost particle tracks is determined from energy deposition $dE/dx$ in the pixel detector. The fraction of lost tracks is found to be less than 5%, which is an improvement since the previous study, and agrees well within systematic uncertainties with a Monte Carlo simulation.

  11. Evaluation of the performance of PRECIL LBY-NJ4A automatic platelet aggregation analyzer%普利生LBY-NJ4A全自动血小板聚集仪性能评价

    Institute of Scientific and Technical Information of China (English)

    石冬敏; 吴元健; 马伟

    2012-01-01

    目的 对普利生LBY-NJ4A全自动血小板聚集仪(NJ4A)进行性能评估.方法 109 mmol/L枸橼酸钠真空管采血,分离富含血小板血浆(PRP)和贫血小板血浆(PPP),应用NJ4A及配套质控品、诱导剂和清洗液,测定血小板最大聚集率(MAR),测试精密度、通道一致性、不确定度、检测限、干扰等.结果 批内不精密度测试,变异系数(CV)为3.4%~5.0%;4个不同通道测定均值差异无统计学意义(P>0.05);携带污染率2.82%;CV批内≤3.5%,CV批间≤4.2%,CV总≤3.8%;总误差范围为5.6%~10.3%,不确定度在可接受范围;2个水平质控品测定值与靶值差异无统计学意义(P>0.05);NJ4A与LBY-NJ2比对结果相关良好(r=0.998,P0.05).结论 NJ4A精密度、准确度、不确定度、灵敏度、携带污染率、抗干扰等性能指标符合CLSI规范,可在临床应用.%Objective To check and evaluate the performance of PRECIL LBY-NJ4A automatic platelet aggregation analyzer (NJ4A) .Methods Blood samples were collected with 109 mmol/L sodium citrate using vacuum tube,then the platelet-rich plasma (PRP)and platelet-poor plasma(PPP) were separated .The NJ4A analyzer with mating quality control,agonists and cleaning solution were used to measure the maximum aggregate rate of platelet (MAR),precision,channel consistency,inaccuracy,detection limitation and inference .Results The precision ranged from 3 .4/0 to 5 .0% .The means of four different channels have no statistically difference(P>0 .05),when carryover rate was 2 .82% .The intra,inter hatch and total coefficient of variance was less than or equal to 3 .5%,4 .2% and 3 .8/0,respectively .The total error ranged from 5 .6/0 to 10 .3%,with an acceptable inaccuracy .Two levels of quality control have no statistically difference with each target value (P>0.05).The correlation of NJ4 and LBY-NJ2 was 0.998 (P0.05) compared to the well-recognized reference range .Conclusion The performance indicators of precision, accuracy, uncertainty

  12. Optical fiber link for transmission of 1-nJ femtosecond laser pulses at 1550 nm.

    Science.gov (United States)

    Eichhorn, Finn; Olsson, Rasmus Kjelsmark; Buron, Jonas C D; Grüner-Nielsen, Lars; Pedersen, Jens Engholm; Jepsen, Peter Uhd

    2010-03-29

    We report on numerical and experimental characterization of the performance of a fiber link optimized for the delivery of sub-100-fs laser pulses at 1550 nm over several meters of fiber. We investigate the power handling capacity of the link, and demonstrate all-fiber delivery of 1-nJ pulses over a distance of 5.3 m. The fiber link consists of dispersion-compensating fiber (DCF) and standard single-mode fiber. The optical pulses at different positions in the fiber link are measured using frequency-resolved optical gating (FROG). The results are compared with numerical simulations of the pulse propagation based on the generalized nonlinear Schrödinger equation. The high input power capacity of the fiber link allows the splitting and distribution of femtosecond pulses to an array of fibers with applications in multi-channel fiber-coupled terahertz time-domain spectroscopy and imaging systems. We demonstrate THz pulse generation and detection using a distributed fiber link with 32 channels and 2.6 nJ input pulse energy.

  13. Preliminary study on plasma membrane fluidity of Psychrophilic Yeast Rhodotorula sp. NJ298 in low temperature

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The ability of cell to modulate the fluidity of plasma membrane was crucial to the survival of microorganism at low temperature. Plasma membrane proteins, fatty acids and carotenoids profiles of Antarctic psychrophilc yeast Rhodotorula sp. NJ298 were investigated at -3 ℃, 0 ℃ and 8 ℃. The results showed that plasma membrane protein content was greater at -3 ℃ than that at 8 ℃, and a unique membrane polypeptide composition with an apparent molecular mass of 94.7 kDa was newly synthesized with SDS-PAGE analysis; GC analysis showed that the main changes of fatty acids were the percentage of unsaturated fatty acids (C18∶ 1 and C18∶ 2) and shorter chain saturated fatty acid (C10∶ 0) increased along with the decrease of the culture temperature from 8 ℃ to -3 ℃; HPLC analysis indicated that astaxanthin was the major functional carotenoids of the plasma membrane, percentage of which increased from 54.6±1.5% at 8 ℃ to 81.9±2.1% at -3 ℃. However the fluidity of plasma membrane which was determined by measuring fluorescence anisotropy was similar at -3 ℃, 0 ℃ and 8 ℃. Hence these changes in plasma membrane's characteristics were involved in the cellular cold-adaptation by which NJ298 could maintain normal plasma membrane fluidity at near-freezing temperature.

  14. Scaling Properties of the D-Short Range Order in PdDx for Higher D Concentrations

    DEFF Research Database (Denmark)

    Krexner, G.; Ernst, G; Fratzl, P.

    1984-01-01

    New measurements of D-short range order (SRO) in PdDx and Pd1−yAgyDx−y are presented. A scaling behaviour of the complicated SRO- features with temperature and electronic concentration is proposed and discussed with respect to the Clapp-Moss-de Fontaine theory of ordering.......New measurements of D-short range order (SRO) in PdDx and Pd1−yAgyDx−y are presented. A scaling behaviour of the complicated SRO- features with temperature and electronic concentration is proposed and discussed with respect to the Clapp-Moss-de Fontaine theory of ordering....

  15. Antistaphylococcal Activity of DX-619 Alone and in Combination with Vancomycin, Teicoplanin, and Linezolid Assessed by Time-Kill Synergy Testing▿ †

    Science.gov (United States)

    Credito, Kim; Lin, Genrong; Appelbaum, Peter C.

    2007-01-01

    Time-kill synergy studies testing in vitro activity of DX-619 alone and with added vancomycin, teicoplanin, or linezolid against 101 Staphylococcus aureus strains showed synergy between DX-619 and teicoplanin at 12 to 24 h in 72 strains and between DX-619 and vancomycin in 28 strains. No synergy was found with linezolid, and no antagonism was observed with any combination. PMID:17261625

  16. Isolation and optimization of production of Astaxanthin from Antarctic yeast Rhodotorula sp.NJ298

    Institute of Scientific and Technical Information of China (English)

    Liu Junling; Miao Jinlai; Sun Xiuqin; Wang Quanfu; Li Guangyou

    2007-01-01

    Rhodotorula sp. NJ298 which could produce carotenoids was isolated from Antarctic sea ice. The major carotenoid was identified as astaxanthin by Liquid Chromatography/Mass Spectrometry(LC/MS), and its content accounted for 87.62% of total carotenoids (1,786 μg/g). High Performance Liquid Chromatogrephy(HPLC)analysis showed that the purity of the astaxanthin reached about 96.16% through a simple purification. Maximum astaxanthin production(1,908/μg/g)was obtained when the yeast was grown at 10℃ in seawater medium containing 5g/L sodium acetate, 5g/L peptone, 0.5g/L NaCl, 0.01g/L KH2P04;0.01g/L MgS04·7H2O and 0.001 g/L FeS04·7H20 at pH 7.5.

  17. Do Affordable Housing Projects Harm Suburban Communities? Crime, Property Values, and Taxes in Mount Laurel, NJ.

    Science.gov (United States)

    Albright, Len; Derickson, Elizabeth S; Massey, Douglas S

    2013-06-01

    This paper offers a mixed-method analysis of the municipal-level consequences of an affordable housing development built in suburban New Jersey. Opponents of affordable housing development often suggest that creating affordable housing will harm surrounding communities. Feared consequences include increases in crime, declining property values, and rising taxes. To evaluate these claims, the paper uses the case of Mt. Laurel, NJ - the site of a landmark affordable housing legal case and subsequent affordable housing development. Employing a multiple time series group control design, we compare crime rates, property values, and property taxes in Mt. Laurel to outcomes in similar nearby municipalities that do not contain comparable affordable housing developments. We find that the opening of the affordable housing development was not associated with trends in crime, property values, or taxes, and discuss management practices and design features that may have mitigated potential negative externalities.

  18. Optical fiber link for transmission of 1-nJ femtosecond laser pulses at 1550 nm

    DEFF Research Database (Denmark)

    Eichhorn, Finn; Olsson, Rasmus Kjelsmark; Buron, Jonas Christian Due

    2010-01-01

    We report on numerical and experimental characterization of the performance of a fiber link optimized for the delivery of sub-100-fs laser pulses at 1550 nm over several meters of fiber. We investigate the power handling capacity of the link, and demonstrate all-fiber delivery of 1-nJ pulses over...... a distance of 5.3 m. The fiber link consists of dispersion-compensating fiber (DCF) and standard single-mode fiber. The optical pulses at different positions in the fiber link are measured using frequency-resolved optical gating (FROG). The results are compared with numerical simulations of the pulse...... propagation based on the generalized nonlinear Schrödinger equation. The high input power capacity of the fiber link allows the splitting and distribution of femtosecond pulses to an array of fibers with applications in multi-channel fiber-coupled terahertz time-domain spectroscopy and imaging systems. We...

  19. Distribution of muscarinic receptor subtypes in rat brain as determined in binding studies with AF-DX 116 and pirenzepine

    Energy Technology Data Exchange (ETDEWEB)

    Giraldo, E.; Hammer, R.; Ladinsky, H.

    1987-03-02

    In vitro competition binding experiments with the selective muscarinic antagonists AF-DX 116 and pirenzepine (PZ) vs /sup 3/H-N-methylscopolamine as radioligand revealed a characteristic distribution of muscarinic receptor subtypes in different regions of rat brain. Based on nonlinear least squares analysis, the binding data were compatible with the presence of three different subtypes: the M/sub 1/ receptor (high affinity for PZ), the cardiac M/sub 2/ receptor (high affinity for AF-DX 116) and the glandular M/sub 2/ receptor (low affinity for PZ and AF-DX 116). The highest proportion of M/sub 1/ receptors was found in the hippocampus, while the cerebellum and the hypothalamus were the regions with the largest fraction of the cardiac M/sub 2/ and glandular M/sub 2/ receptors, respectively. In certain brain areas, depending on the relative proportions of the subtypes, flat binding curves were seen for AF-DX 116 and PZ. Based on these data, an approximate distribution pattern of the subtypes in the various brain regions is presented. 19 references, 1 figure, 2 tables.

  20. Utilization of dE/dx approx E sup n /a dependence for DELTA E - E-spectrometer calibration

    CERN Document Server

    Gorpinich, O K; Jachmenov, O O

    2002-01-01

    The method of calibration of DELTA E - E-spectrometers by the use of known empiric form dE/dx approx E sup n /a which describes the specific energy loss of charge particles in the matter for energy calibration of DELTA E - E-spectrometer was designed.

  1. Su(dx) E3 ubiquitin ligase-dependent and -independent functions of polychaetoid, the Drosophila ZO-1 homologue.

    Science.gov (United States)

    Djiane, Alexandre; Shimizu, Hideyuki; Wilkin, Marian; Mazleyrat, Sabine; Jennings, Martin D; Avis, Johanna; Bray, Sarah; Baron, Martin

    2011-01-10

    Zona occludens (ZO) proteins are molecular scaffolds localized to cell junctions, which regulate epithelial integrity in mammals. Using newly generated null alleles, we demonstrate that polychaetoid (pyd), the unique Drosophila melanogaster ZO homologue, regulates accumulation of adherens junction-localized receptors, such as Notch, although it is dispensable for epithelial polarization. Pyd positively regulates Notch signaling during sensory organ development but acts negatively on Notch to restrict the ovary germline stem cell niche. In both contexts, we identify a core antagonistic interaction between Pyd and the WW domain E3 ubiquitin ligase Su(dx). Pyd binds Su(dx) directly, in part through a noncanonical WW-binding motif. Pyd also restricts epithelial wing cell numbers to control adult wing shape, a function associated with the FERM protein Expanded and independent of Su(dx). As both Su(dx) and Expanded regulate trafficking, we propose that a conserved role of ZO proteins is to coordinate receptor trafficking and signaling with junctional organization.

  2. Effects of Temperature and Several Chemicals on Metabolic Changes During Dormancy Release in NJ72 Nectarine

    Institute of Scientific and Technical Information of China (English)

    YUAN Zhi-you; LI Xian-li; LI Ling-hao; HAN Xing-guo; YAN Tian-li

    2003-01-01

    Poor, delayed and ununiform budbreak is a major problem for peaches in greenhouse. To clari-fy the mechanism of breaking bud dormancy in nectarines, the effect of temperature and three dormancy-breaking agents on metabolic changes during dormancy release in two-year old NJ72 nectarine (Prunus persicaL. Batch) was investigated. The result showed temperature and chemicals affected the budbreak and the me-tabolism of NJ72 nectarine during dormancy. Endogeneons peroxide content in buds increased soon after lowtemperature treatment. Meanwhile, catalase activity was also shown to increase significantly at low temperature treatment, coincided with increase of the activity of peroxidase and superoxide dismntase. The rate of res-piration in flower buds increased at low temperature during dormancy. The rate of the pentose phosphate path-way increased, while the rate of the Embden-Meyerhof pathway decreased and the rate of triearboxlic acid cycle changed little. Glucose 6-phosphate dehydrogenase activity increased at low temperature during dormancy.At the same time we found an accumulation of peroxide after treatment with dormancy-breaking chemicals. Inflower buds treated with dormancy-breaking agents, thiourca, KNO3 and NH4 NO3, catalase activity was in-hibited soon after treatment, whereas peroxidase activity increased, and the changes of superoxide dismutaseremained little. In this study, it was found that the rates of respiration in flower buds increased by chemicalssprays during dormancy. The activity of glucose 6-phosphate dehydrogenase, the key enzyme in the pentosephosphate pathway (PPP), increased by spraying with dormancy-breaking agents, concomitantly with the ac-tivatlon of the pentose phosphate pathway.

  3. Correlation of Oncotype DX Recurrence Score with Histomorphology and Immunohistochemistry in over 500 Patients

    Science.gov (United States)

    Hanna, Matthew G.; Bleiweiss, Ira J.; Nayak, Anupma

    2017-01-01

    Oncotype Dx is used to determine the recurrence risk (RR) in patients with estrogen receptor positive (ER+) and lymph node negative (LN−) breast cancer. The RR is divided into low (0–17), intermediate (18–30), and high (31) to predict chemotherapy benefit. Our goal was to determine the association between histomorphology, immunohistochemistry, and RR. We retrospectively identified 536 patients with ER+ and LN− breast cancers that underwent Oncotype testing from 2006 to 2013. Tumor size ranged from 0.2 cm to 6.5 cm (mean = 1.3 cm) and was uniform in all 3 categories. The carcinomas were as follows: ductal = 63.2%, lobular = 11.1%, and mixed = 35.7%. The RR correlated with the Nottingham grade. Increasing RR was inversely related to PR positivity but directly to Her2 positivity. Of the morphologic parameters, a tubular(lobular) morphology correlated only with low-intermediate scores and anaplastic type with intermediate-high scores. Other morphologies like micropapillary and mucinous were uniformly distributed in each category. Carcinomas with comedo intraductal carcinoma were more likely associated with high RR. Forty-four patients with either isolated tumor cells or micrometastases were evenly distributed amongst the 3 RR. While there was only 1 ER discrepancy between our immunohistochemistry (3+ 80%) and Oncotype, up to 8% of PR+ cases (mean = 15%, median = 5%) and 2% of HER2+ cases were undervalued by Oncotype. PMID:28168058

  4. 77 FR 3499 - Sony Electronics, Inc., Including On-Site Leased Workers From Selectremedy Park Ridge, NJ...

    Science.gov (United States)

    2012-01-24

    ...] Sony Electronics, Inc., Including On-Site Leased Workers From Selectremedy Park Ridge, NJ; Amended... of Sony Electronics, Inc., SEL Headquarters, including on-site leased workers of SelectRemedy, StaffMark, and Payrolling.com , San Diego, California (TA-W-71,501); Sony Electronics, Inc., including...

  5. Constructing A New Japanese Development Design Model NJ-DDM: Intellectual Evolution of an Automobile Product Design

    Directory of Open Access Journals (Sweden)

    Kakuro Amasaka

    2015-11-01

    Full Text Available The author constructs a New Japanese Development Design Model “NJ-DDM” utilizing CAE to realize “simultaneous achievement of QCD” (quality, cost and delivery in automobile development design by evolving the super-short-term development design process. Based on this, the author verifies the validity of this model in intellectual evolution of an automobileproduct design.

  6. U.S. EPA’s Technical Support for the Reich Farm (Toms River, NJ) Superfund Site Remediation

    Science.gov (United States)

    PowerPoint slide file that gives a brief history of the SAN Trimer contamination in Toms River, NJ as well as the EPA's provided technical support, specifically the development and application of the Provisional Peer-Reviewed Toxicity Value (PPRTV) assessment for SAN Trimer.

  7. 77 FR 34285 - Safety Zone; 2012 Ironman U.S. Championship Swim, Hudson River, Fort Lee, NJ

    Science.gov (United States)

    2012-06-11

    ... the January 17, 2008, issue of the Federal Register (73 FR 3316). Public Meeting We do not plan now to... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; 2012 Ironman U.S. Championship Swim, Hudson... vicinity of Englewood Cliffs and Fort Lee, NJ for the 2012 Ironman U.S. Championship swim event....

  8. Evaluation for clinical application of UniCel DxH 800 hematology analyzer%UniCel DxH 800血细胞分析仪临床应用评价

    Institute of Scientific and Technical Information of China (English)

    普程伟; 明秀芬; 尚柯; 王建中; 刘雪凯; 邢莹; 汤晓凌; 高辉; 董宁; 苏惠青

    2012-01-01

    目的 探讨UniCel DxH 800全自动血细胞分析仪检测全血细胞计数(CBC)的相关性能,并与LH 750和ADVIA 2120全自动血细胞分析仪及显微镜白细胞分类计数比较.方法 使用新鲜血标本和仪器配套质控品评价UniCel DxH 800测定CBC的精密度、携带污染率和线性范围;以显微镜法为“金标准”,评价其白细胞分类计数和网织红细胞计数的准确性;计算UniCel DxH 800与LH750和ADVIA 2120血细胞分析仪测定结果的偏差和相关性,并比较3种仪器对异常细胞报警的有效性.结果 UniCel DxH 800测定RBC、Hb和MCV的批内精密度(CV)<0.5%,WBC和PLT的批内CV<1.5%.上述5项参数的批间CV均<2.5%,携带污染率均<0.51%.在临床样本所覆盖的浓度范围内,WBC、RBC、Hb、PLT测定值与理论值呈线性相关(r>0.999,P<0.01).UniCel DxH 800与LH 750、ADVIA 2120血液分析仪对WBC、RBC、Hb、MCV和PLT的测定结果有良好的相关性(r >0.973,P<0.01).UniCel DxH 800血细胞分析仪计数网织红细胞与显微镜法计数的相关性较好(r =0.920,P<0.01).UniCei DxH 800血液分析仪与显微镜法分类计数白细胞比较,中性粒细胞、淋巴细胞和嗜酸粒细胞的相关性较好(r值分别为0.914、0.900和0.725,P<0.01),其次为单核细胞(r =0.612,P<0.01),优于类似检测原理的LH 750.UniCel DxH 800对异常细胞报警的敏感度为96.6%,假阴性率为2.5%;对中性粒细胞核左移的敏感度为90.5%,假阴性率为5.0%.结论 UniCel DxH 800全自动血液分析仪用于全血细胞计数具有高精密度、低携带污染率和宽线性范围的优点,与LH 750和ADVIA 2120全自动血液分析仪的检测结果具有良好的相关性.%Objective To evaluate the improvement on test performance of UniCel DxH 800 automated hematology analyzer for complete blood count (CBC) by detecting its performance indicators and comparing the differences of the results with LH 750 hematology

  9. the dE / dx Capabilities of the D0 Tracking System

    Energy Technology Data Exchange (ETDEWEB)

    Rajagopalan, Srinivasan [Northwestern Univ., Evanston, IL (United States)

    1992-06-01

    The D0 forward tracking system has been extensively calibrated using electron and pion beams in the energy range from 10 GeV to 150 GeV in the neutrino area fixed target beam line at Fermilab. The forward tracking system provides a spatial resolution of 200 $\\mu m$ and a two hit separation of 2.5 mm at 90% efficiency. The chamber provides 32 samples of pulse height information for a given track equivalent to a dEjdx resolution of 12.7%. The energy loss response of the chamber to low energy· beam has been studied. A Monte Carlo simulation program has been developed based on the Photo Absorption Ionization model to simulate the dEjdx response of the chamber. The observations made using low energy test beam are consistent with the model's predictions. The dE/dx measurement in the D0 tracking system provides identification of electrons against gamma conversions resulting from $\\pi^0$ decays. The rejection factor of distinguishing doubly minimum ionizing tracks in the chamber has been measured to be 30.5 with the requirement that singly minimum ionizing tracks be identified with a 90% efficiency. This factor improves with lower multiplicity. Using a Monte Carlo program based on GEANT, the identification efficiency of electrons and $\\pi^0$'S has been determined. Using the capabilities of the outer tracking system alone, the background due to isolated $\\pi^0$ production is reduced by up to a factor of 60 in the central direction based on measurements made on a sample of simulated QCD two jet events.

  10. Association Between Phosphorylated Histone H3 and Oncotype DX Recurrence Scores in Breast Cancer

    Science.gov (United States)

    Lee, Lik Hang; Swanson, Paul E.; Tang, Patricia A.; Bigras, Gilbert

    2017-01-01

    We investigate the association between phosphorylated histone H3 (PhH3) and Oncotype DX recurrence score (RS). All invasive breast carcinoma with RS results from our city between 2007 and 2010 (n=47) were reviewed. Whole-tumor sections were stained for PhH3. Mitotic and PhH3 counts were performed and clinical charts reviewed. PhH3 correlated well with RS (r=0.69, P<0.001). Other correlations were: PhH3 versus mitotic count (r=0.87, P<0.001), PhH3 versus mitotic score (r=0.71, P<0.001), PhH3 versus modified Bloom-Richardson-Elston (MBR) grade (r=0.65, P<0.001), RS versus mitotic count (r=0.62, P<0.001), RS versus mitotic score (r=0.44, P=0.002), and RS versus MBR grade (r=0.49, P=0.001). Significant correlation between PhH3 and RS remained after controlling for mitotic count (r=0.39, P=0.007), mitotic score (r=0.60, P<0.001), MBR grade (r=0.56, P<0.001), and all 3 (r=0.37, P=0.014) by partial correlation. Two patients died of metastasis at 12 and 38 months after diagnosis. One had intermediate RS, and 1 high RS; both were in the top-third of PhH3 count. All other patients are alive and recurrence free. Correlation between PhH3 and RS was statistically significant in our cohort, and remained significant after controlling for traditional measures of proliferation. Given that RS has an established strong relationship with prognosis and therapy responsiveness, PhH3 may thus also be an important prognostic/predictive marker in breast cancer. PMID:26371428

  11. Evaluation of Hologic Aptima HIV-1 Quant Dx Assay on the Panther System on HIV Subtypes.

    Science.gov (United States)

    Manak, Mark M; Hack, Holly R; Nair, Sangeetha V; Worlock, Andrew; Malia, Jennifer A; Peel, Sheila A; Jagodzinski, Linda L

    2016-10-01

    Quantitation of the HIV-1 viral load in plasma is the current standard of care for clinical monitoring of HIV-infected individuals undergoing antiretroviral therapy. This study evaluated the analytical and clinical performances of the Aptima HIV-1 Quant Dx assay (Hologic, San Diego, CA) for monitoring viral load by using 277 well-characterized subtype samples, including 171 cultured virus isolates and 106 plasma samples from 35 countries, representing all major HIV subtypes, recombinants, and circulating recombinant forms (CRFs) currently in circulation worldwide. Linearity of the Aptima assay was tested on each of 6 major HIV-1 subtypes (A, B, C, D, CRF01_AE, and CRF02_AG) and demonstrated an R(2) value of ≥0.996. The performance of the Aptima assay was also compared to those of the Roche COBAS AmpliPrep/COBAS TaqMan HIV-1 v.2 (CAP/CTM) and Abbott m2000 RealTime HIV-1 (RealTime) assays on all subtype samples. The Aptima assay values averaged 0.21 log higher than the CAP/CTM values and 0.30 log higher than the RealTime values, and the values were >0.4 log higher than CAP/CTM values for subtypes F and G and than RealTime values for subtypes C, F, and G and CRF02_AG. Two samples demonstrated results with >1-log differences from RealTime results. When the data were adjusted by the average difference, 94.9% and 87.0% of Aptima results fell within 0.5 log of the CAP/CTM and RealTime results, respectively. The linearity and accuracy of the Aptima assay in correctly quantitating all major HIV-1 subtypes, coupled with the completely automated format and high throughput of the Panther system, make this system well suited for reliable measurement of viral load in the clinical laboratory. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  12. DX600发射机变频风机控制器故障分析与处理

    Institute of Scientific and Technical Information of China (English)

    关芳

    2015-01-01

    DX600发射机变频风机控制器是发射机的重要部分,如果这部分出现故障将造成停播.本文介绍了DX600发射机并机网络冷却控制部分一例典型故障的分析、查找及处理过程,详细分析了BALDOR风机控制器故障原因,希望能给维护同类型发射机的单位提供一定的借鉴和参考.

  13. SN 2013dx associated with GRB 130702A: a detailed photometric and spectroscopic monitoring and a study of the environment

    Science.gov (United States)

    D'Elia, V.; Pian, E.; Melandri, A.; D'Avanzo, P.; Della Valle, M.; Mazzali, P. A.; Piranomonte, S.; Tagliaferri, G.; Antonelli, L. A.; Bufano, F.; Covino, S.; Fugazza, D.; Malesani, D.; Møller, P.; Palazzi, E.

    2015-05-01

    Aims: Long-duration gamma-ray bursts (GRBs) and broad-line, type Ic supernovae (SNe) are strongly connected. We aim at characterizing SN 2013dx, which is associated with GRB 130702A, through a sensitive and extensive ground-based observational campaign in the optical-IR band. Methods: We monitored the field of the Swift GRB 130702A (redshift z = 0.145) using the 8.2 m VLT, the 3.6 m TNG and the 0.6 m REM telescopes during the time interval between 4 and 40 days after the burst. Photometric and spectroscopic observations revealed the associated type Ic SN 2013dx. Our multiband photometry allowed constructing a bolometric light curve. Results: The bolometric light curve of SN 2013dx resembles that of 2003dh (associated with GRB 030329), but is ~10% faster and ~25% dimmer. From this we infer a synthesized 56Ni mass of ~0.2 M⊙. The multi-epoch optical spectroscopy shows that the SN 2013dx behavior is best matched by SN 1998bw, among the other well-known low-redshift SNe associated with GRBs and XRFs, and by SN 2010ah, an energetic type Ic SN not associated with any GRB. The photospheric velocity of the ejected material declines from ~2.7 × 104 km s-1 at 8 rest frame days from the explosion, to ~3.5 × 103 km s-1 at 40 days. These values are extremely close to those of SN1998bw and 2010ah. We deduce for SN 2013dx a kinetic energy of ~35 × 1051 erg and an ejected mass of ~7 M⊙. This suggests that the progenitor of SN2013dx had a mass of ~25-30 M⊙, which is 15-20% less massive than that of SN 1998bw. Finally, we studied the SN 2013dx environment through spectroscopy of the closeby galaxies: 9 out of the 14 inspected galaxies lie within 0.03 in redshift from z = 0.145, indicating that the host of GRB 130702A/SN 2013dx belongs to a group of galaxies, an unprecedented finding for a GRB-associated SN and, to our knowledge, for long GRBs in general. Based on observations collected at the Italian 3.6-m Telescopio Nazionale Galileo (TNG), operated on the island of La

  14. CLSI-based transference of the CALIPER database of pediatric reference intervals to Beckman Coulter DxC biochemical assays.

    Science.gov (United States)

    Araújo, Petra A T; Thomas, Dylan; Sadeghieh, Tara; Bevilacqua, Victoria; Chan, Man Khun; Chen, Yunqi; Randell, Edward; Adeli, Khosrow

    2015-09-01

    The CALIPER program has established a comprehensive database of age- and sex-stratified pediatric reference intervals for over 85 common biochemical markers, largely using the Abbott ARCHITECT assays. To allow a broader application of the CALIPER database, we examined transference to 36 Beckman Coulter Synchron Unicel DxC800 assays, based on the CLSI C28-A3/EP9-A3 guidelines. Patient sample comparisons were performed for 36 biochemical assays using 200 serum specimens obtained from pediatric patients on the Abbott ARCHITECT ci8200 and the Beckman Coulter DxC800. For each analyte, R(2) values were calculated to assess the quality of correlation between the platforms. Statistical criteria used to assess transferability included a) regression analysis to create the equation of the line of best fit, b) standardized residual, c) Bland-Altman, and d) quantile-quantile plots. Transferred reference intervals were further verified by analyzing serum samples from 100 healthy children from the CALIPER cohort on the Beckman Coulter system. The reference intervals for most of the assessed analytes were transferable to Beckman Coulter assays (31 out of 36 studied) and the newly calculated reference intervals were verified through analysis of CALIPER reference samples (28 out of 31). Eighteen assays demonstrated excellent correlation (R(2)≥0.95), and 13 assays showed strong correlation (0.77≤R2≤0.94). The current study allowed successful transference of a large number of biochemical markers from the CALIPER database to assays on the Beckman Coulter DxC800 platform. Transference should facilitate broader application of CALIPER reference intervals at pediatric centers using DxC biochemical assays. Copyright © 2015 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  15. Oxygen loss induced by swift heavy ions of low and high dE/dx in PMMA thin films

    Science.gov (United States)

    Thomaz, R.; Gutierres, L. I.; Morais, J.; Louette, P.; Severin, D.; Trautmann, C.; Pireaux, J. J.; Papaléo, R. M.

    2015-12-01

    Investigations on the chemical modifications induced by swift heavy ions in PMMA thin films were carried out using beams of high dE/dx (2.2 GeV Bi, 14,090 eV/nm) and low dE/dx (2 MeV H, 19 eV/nm). The induced chemical modifications were monitored by XPS for films with initial thickness of 50 and 100 nm. For both beams, the irradiation decreased the amount of carbon atoms bound to oxygen (Cdbnd O and Csbnd Osbnd C), with a larger decrease of the carboxyl moiety, as expected. However, the chemical changes induced by light and heavy ions were qualitatively different. For the same mean deposited energy density, proton irradiation induced a decrease of the relative intensity of the carbon-oxygen bonds up to ∼20% larger than the irradiation with Bi ions. This suggests a greater importance of particle ejection by unzipping of PMMA chains at high dE/dx, which tends to keep the O/C ratio closer to the pristine value.

  16. Oxygen loss induced by swift heavy ions of low and high dE/dx in PMMA thin films

    Energy Technology Data Exchange (ETDEWEB)

    Thomaz, R.; Gutierres, L.I. [Faculdade de Física, Pontifícia Universidade Católica do Rio Grande do Sul, Av. Ipiranga 6681, 90619-900 Porto Alegre (Brazil); Morais, J. [Instituto de Física, Universidade Federal do Rio Grande do Sul, Av Bento Gonçalves 9500, 91501-970 Porto Alegre (Brazil); Louette, P. [Université de Namur, Rue de Bruxelles 61, 5000 Namur (Belgium); Severin, D. [Materials Research, GSI Helmholtz Centre, Planckstr. 1, 64291 Darmstadt (Germany); Trautmann, C. [Materials Research, GSI Helmholtz Centre, Planckstr. 1, 64291 Darmstadt (Germany); Technische Universität Darmstadt, Alarich-Weiss-Straße2, 64287 Darmstadt (Germany); Pireaux, J.J. [Université de Namur, Rue de Bruxelles 61, 5000 Namur (Belgium); Papaléo, R.M. [Faculdade de Física, Pontifícia Universidade Católica do Rio Grande do Sul, Av. Ipiranga 6681, 90619-900 Porto Alegre (Brazil)

    2015-12-15

    Investigations on the chemical modifications induced by swift heavy ions in PMMA thin films were carried out using beams of high dE/dx (2.2 GeV Bi, 14,090 eV/nm) and low dE/dx (2 MeV H, 19 eV/nm). The induced chemical modifications were monitored by XPS for films with initial thickness of 50 and 100 nm. For both beams, the irradiation decreased the amount of carbon atoms bound to oxygen (C=O and C−O−C), with a larger decrease of the carboxyl moiety, as expected. However, the chemical changes induced by light and heavy ions were qualitatively different. For the same mean deposited energy density, proton irradiation induced a decrease of the relative intensity of the carbon–oxygen bonds up to ∼20% larger than the irradiation with Bi ions. This suggests a greater importance of particle ejection by unzipping of PMMA chains at high dE/dx, which tends to keep the O/C ratio closer to the pristine value.

  17. Hurricane Sandy puts NJ hospital under extreme stress, highlighting vulnerabilities, areas requiring improvement.

    Science.gov (United States)

    2013-01-01

    When monster storm, Hurricane Sandy, struck the northeastern coast in late October, the emergency systems for many hospitals in the region were stressed beyond their limits. At least four hospitals in the region had to be evacuated, and many hospitals lost power and access to essential services. Using backup generators, CentraState Medical Center in Freehold, NJ, was able to keep its doors open throughout the emergency, but the event highlighted a number of vulnerabilities that administrators will work to improve. Demand for care spiked because people in the hospital's service area could not get in to see their primary care providers. The hospital established care areas next to its emergency department to handle the demand, and it also enabled physicians in the region to see patients in offices on an ambulatory campus, adjacent to the hospital. Emergency department visits increased by about 41% during the hurricane week, admits went up by about 50%, and the number patients sent to observation went up by 450%, according to hospital administrators. In the future, hospital leaders say practice drills need to regularly test for events that cause many systems to go down, rather then testing for one vulnerability at a time.

  18. A note on the connectedness locus of the families of polynomials Pc(z=z n - cz n-j

    Directory of Open Access Journals (Sweden)

    Carlos Arteaga

    2012-03-01

    Full Text Available Let j be a positive integer. For each integer n > j we consider the connectedness locus Mn of the family of polynomials Pc(z = z n - cz n-j, where c is a complex parameter. We prove that lim n→∞ Mn = D in the Hausdorff topology, where D is the unitary closed disk {c;|c|Seja j um inteiro positivo. Para cada inteiro n > j, consideramos o locus conexo Mn da família de polinômios Pc(z = z n - cz n-j, onde c é um parâmetro complexo. Provamos que lim n→∞ Mn = D na topologia de Hausdorff; onde D é o disco unitário {c;|c|<1}.

  19. [Colonization characteristics of endophytic bacteria NJ13 in Panax ginseng and its biocontrol efficiency against Alternaria leaf spot of ginseng].

    Science.gov (United States)

    Chen, Chang-Qing; Li, Tong; Li, Xin-Lian; Jiang, Yun; Tian, Lei; Xu, Peng

    2014-05-01

    To reveal the colonization characteristics in host of endophytic biocontrol bacteria NJ13 isolated from Panax ginseng, this study obtained the marked strain NJ13-R which was double antibiotic resistant to rifampicin and streptomycin through enhancing the method of inducing antibiotic. The colonization characteristics in ginseng and its biocontrol efficiency against Alternaria spot of ginseng in the field were studied. The results showed that the strain could colonize in root, stem and leaf of ginseng and the colonization amount was positive correlated with inoculation concentration. Meanwhile, the strain could infect and then transfer in different tissues of ginseng The colonization amount of strain in roots and leaves of ginseng increased first and then decreased. However, the tendency of colonization amount of strain in stems was ascend at first and then descend slowly, and was more than that in roots and leaves along with time, which had a preference to specific tissue of its host. In field experiment, the endophytic bacteria NJ13 was proved to be effective in controlling Alternaria leaf spot of ginseng. The biocontrol efficiency of fermentation broth at the concentration of 0.76 x 10(8) cfu x mL(-1) reached 75.62%, which was close to the controlling level (73.06%) of 0.67 mg x L(-1) 50% cyprodinil WG.

  20. Multiconfigurate character of the DX center and statistical analysis of transport data in Si-doped Al{sub x}Ga{sub 1-x}As

    Energy Technology Data Exchange (ETDEWEB)

    Triki, A.; Rziga Ouaja, F.; Selmi, A. [Dept. de Physique, Faculte des Sciences, Monastir (Tunisia); Mejri, H. [Dept. de Physique, Faculte des Sciences, Monastir (Tunisia)

    2001-10-01

    Two statistics are developed using the multiconfigurate character of the DX center to analyse donors in n-type Al{sub x}Ga{sub 1-x}As:Si. The first statistics is derived assuming that the conduction electrons arise exclusively from DX centers. The second statistics supposes the existence of shallow donors in addition to the deep DX center. Experimental Hall data, obtained in Al{sub x}Ga{sub 1-x}As:Si grown by metalorganic chemical vapor deposition, are interpreted using these statistical calculations. (orig.)

  1. Attracting Urban Minority Students to Geosciences through Exposure to Careers and Applied Aspects in Newark, NJ

    Science.gov (United States)

    Gates, A. E.; Kalczynski, M. J.

    2014-12-01

    A solid pipeline of URM students into the Geosciences has been established in Newark, NJ by introducing them to applied opportunities. Prior to an OEDG program designed to engage URM students, there were no students from or near Newark interested in pursuing geosciences at Rutgers-Newark or Essex Community College, the two local urban campuses. By infusing activities that showed the applied aspects of geoscience and opportunities for careers into regular high school lesson plans, a significant number of students became interested. These students were recruited into a 4-week modular summer institute that focused on energy, mining resources, environment and surface processes. About 90 students per year attended the institute which included 2 local field trips per week, presentations by industry professionals, activities that placed academic subjects into career perspective and a research project that directly affected the well-being of the students and their families. The most interested dozen of the 90 students were invited to participate in a high profile applied project that received significant media coverage, further enhancing their impression of the importance of geosciences. Previous graduates of the program were employed as assistants in subsequent programs to recycle the experience and enthusiasm. This had a positive effect on the persistence of the assistants who viewed themselves as role models to the younger students. The results are burgeoning numbers of URM geoscience majors at Rutgers, offering of geoscience for the first time in 30 years at Essex Community College as well as a new 2+2 geoscience track and several dual-credit courses at local high schools. An important aspect of this pathway or pipeline is that students must be able to clearly see the next step and their role in it. They are very tentative in this essentially pioneering pursuit. If they don't get a sense of a welcoming community and an ultimate career outcome, they quickly lose

  2. Mapas de Entornos Mediante Navegacion Difusa y Sistema de Teleoperacion de una Plataforma Pioneer P3-DX

    Directory of Open Access Journals (Sweden)

    Daniel Granda

    2013-11-01

    Full Text Available El presente proyecto describe el diseno e implementacion de aplicaciones de Teleoperacion, Adquisicion de Datos, Control Difuso de Velocidad y Mapeo de Entornos en 2D, para la plataforma movil Pioneer P3-DX mediante el uso de sonares, odometrıa y software libre GNU/Linux. El proyecto brinda una guıa para utilizar los conceptos de programacion en Python, que permite crear aplicaciones de manera versatil mediante el uso de librerıas como: GTK para el desarrollo del entorno grafico, PYFUZZY para el desarrollo del controlador difuso de velocidad y OPENCV para mostrar los mapas del entorno.

  3. Substitutionality of Te- and Sn-related DX centers in Al sub x Ga sub 1 minus x As

    Energy Technology Data Exchange (ETDEWEB)

    Yu, K.M. (Center for Advanced Materials, Materials and Chemical Sciences Division, Lawrence Berkeley Laboratory, Berkeley, California 94720 (USA)); Khachaturyan, K.; Weber, E.R. (Center for Advanced Materials, Materials and Chemical Sciences Division, Lawrence Berkeley Laboratory, Berkeley, California (USA) Department of Materials Science and Mineral Engineering, University of California, Berkeley, California (USA)); Lee, H.P. (Department of Electrical Engineering and Computer Science, University of California, Berkeley, California (USA)); Kolas, E.G. (Bell Communication Research Inc., Red Bank, New Jersey (USA))

    1991-01-15

    The lattice locations of Te and Sn atoms forming {ital DX} centers in Al{sub {ital x}}Ga{sub 1{minus}{ital x}}As were determined by particle-induced x-ray emission and ion-beam-channeling methods. The Te atoms were found to be in the As substitutional sites while the Sn atoms were in the Ga(Al) sites. No off-center displacement of Te and Sn larger than 0.14 A from the substitutional sites was observed in either system.

  4. The Conformation and Assignment of the Proton NMR Spectrum in Water of DX600, a Bioactive Peptide with a Random Coil Conformation

    Directory of Open Access Journals (Sweden)

    Wayne E. Steinmetz

    2011-01-01

    Full Text Available DX600, a small peptide with 26 residues, is a potent, highly selective inhibitor of angiotensin converting enzyme 2 (ACE2. A range of NMR methods including TOCSY and ROESY yield an assignment of its proton spectrum in water and constraints on its conformation. Constrained molecular dynamics simulations of solvated DX600 show that the peptide's most abundant conformer adopts a predominantly random coil conformation. Constrained by the disulfide bond, its backbone defines an overhand knot with frayed ends.

  5. Role Models and Mentors in Mid-Pipeline Retention of Geoscience Students, Newark, NJ

    Science.gov (United States)

    Gates, A. E.; Kalczynski, M. J.

    2012-12-01

    Undergraduate minority students retained enthusiasm for majoring in the geosciences by a combination of working with advanced minority mentors and role models as well as serving as role models for middle and high school students in Geoscience Education programs in Newark, NJ. An academic year program to interest 8-10th grade students from the Newark Public schools in the Geosciences employs minority undergraduate students from Rutgers University and Essex Community College as assistants. There is an academic year program (Geoexplorers) and a science festival (Dinosaur Day) at the Newark Museum that employs Rutgers University students and a summer program that employs Rutgers and Essex Community College students. All students are members of the Garden State LSAMP and receive any needed academic support from that program. The students receive mentoring from minority graduate students, project personnel and participating Newark Public School teachers, many of whom are from minority groups. The main factor in success and retention, however, is their role as authorities and role models for the K-12 students. The assistants are respected and consulted by the K-12 students for their knowledge and authority in the geosciences. This positive feedback shows them that they can be regarded as geoscientists and reinforces their self-image and enthusiasm. It further reinforces their knowledge of Geoscience concepts. It also binds the assistants together into a self-supporting community that even extends to the non-participating minority students in the Rutgers program. Although the drop-out rate among minority Geoscience majors was high (up to 100%) prior to the initiation of the program, it has dropped to 0% over the past 3 years with 2 participants now in PhD programs and 2 others completing MS degrees this year. Current students are seriously considering graduate education. Prior to this program, only one minority graduate from the program continued to graduate school in the

  6. Optimization of Regeneration System of Tissue Culture and Transformation of 1Dx5 Gene without Markers in Wheat

    Directory of Open Access Journals (Sweden)

    Jianbing Qin

    2013-01-01

    Full Text Available To improve bread making quality of flour and produce transgenic plants free of selectable markers, Immature embryo scutella from Xindong No. 26 were used as explants for establishing an efficient and stable wheat regeneration system, then he linear expressing box of 1Dx5 without selectable markers was transformed into the immature embryo of Xin Dong No. 26 via particle bombardment. The result showed that MS medium containing 2, 4-D 1.5 mg/L and Dicamba 0.5 mg/L for callus induction, R medium containing ZT 1 mg/Land 2,4-D 0.01 mg/L for callus differentiation were the best efficiency, the differentiation frequency of callus was 90%; Transformed plants were screened by PCR, three transgenic plants were detected among 1000 transformed plants, only yielding the transformation rate of 0.3%. The compositions of HWM-GS were analyzed by SDS-PAGE. The HMW-GS gene 1Dx5 was expressed in some seeds of transgenic plants. Our studies lay the foundations for obtaining marker-free transformants using the linear gene via particle bombardment.

  7. Comparison of anti-M2-muscarinic effect of AF-DX 116 on atrioventricular nodal conduction with those of pirenzepine and atropine as antibradyarrhythmic drugs.

    Science.gov (United States)

    Sasaki, S; Motomura, S

    1999-06-01

    Selectivity of antimuscarinic actions of AF-DX 116 (AF-DX) on the atrioventricular (AV) nodal conduction was compared with those of pirenzepine and atropine by using the canine isolated, blood-perfused AV node preparation and the open-chest in situ dog heart. In the isolated AV node preparation, dose-response curves for negative dromotropic effects (prolongation of Atrio-His interval) of carbachol (CCh) injected into the posterior septal artery were shifted to the right in parallel by AF-DX, pirenzepine, and atropine with apparent pA2-values of 13, 27.5, and 0.45 microg, respectively, and slopes of the modified Schild plot of nearly unity. Meanwhile, dose-response curves for coronary vasodilator effects of CCh were shifted to the right by AF-DX, pirenzepine, and atropine with the apparent pA2 values of 68, 12.5, and 0.55 microg, respectively, but the slopes were far from unity. In the in situ open-chest heart, dose-response curves for negative dromotropic effects (prolongation of AV conduction time) of CCh given intravenously were shifted to the right in parallel by AF-DX, pirenzepine, and atropine with apparent pA2 values of 36, 32, and 1.25 microg/kg, respectively, and the slope of nearly unity, whereas dose-response curves for hypotensive effects of CCh were shifted to the right by AF-DX, pirenzepine, and atropine with apparent pA2 values of 105, 15, and 0.65 microg/kg, respectively, but the slopes of AF-DX and pirenzepine were far from unity. In addition, prolongations of AV conduction time by electrical stimulation of the left vagus nerve in the in situ heart were suppressed by AF-DX, pirenzepine, and atropine with the ID50, dose for 50% suppression, of 40, 35, and 1.9 microg/kg, respectively. These results suggest that (a) the potency of antimuscarinic actions of AF-DX on the CCh-induced negative dromotropic effects was almost equal to that of pirenzepine, and approximately 30 times less potent than atropine; (b) the M2-subtype selectivity of AF-DX was

  8. Generation of 8-nJ pulses from a dissipative-soliton fiber laser with a nonlinear optical loop mirror

    Science.gov (United States)

    Zhao, L. M.; Bartnik, A. C.; Tai, Q. Q.; Wise, F. W.

    2013-01-01

    Theoretical and experimental investigations of the behavior of normal-dispersion fiber lasers with nonlinear-optical loop mirrors are presented. The use of a loop mirror causes the laser to generate relatively long, flat-topped pulses. The pulse energy can be high, but the pulse duration is limited to greater than 300 fs. Experimentally, 8-nJ pulses that can be dechirped to 340 fs duration are obtained. The laser is a step toward an all-fiber, environmentally-stable design. PMID:23722797

  9. Dissecting the Disulfide Linkage of the N-Terminal Domain of HMW 1Dx5 and Its Contributions to Dough Functionality.

    Science.gov (United States)

    Wang, Jing Jing; Liu, Guang; Huang, Yan-Bo; Zeng, Qiao-Hui; Hou, Yi; Li, Lin; Ou, Shiyi; Zhang, Min; Hu, Song-Qing

    2017-08-02

    The N-terminal domain of HMW-GS 1Dx5 (1Dx5-N) contains three cysteine residues (Cys10, Cys25, Cys40), which are the basis of gluten network formation through disulfide bonds. Disulfide linkage in 1Dx5-N was dissected by site-directed mutagenesis and LC-MS/MS, and its contributions to structural and conformational stability of 1Dx5-N and dough functionality were investigated by circular dichroism, intrinsic fluorescence, surface hydrophobicity determination, size exclusion chromatography, nonreducing/reducing SDS-PAGE, atomic force microscopy, and farinographic analysis. Results showed that Cys10 and Cys40 of 1Dx5-N were the active sites for intermolecular linkage. Meanwhile, Cys40 also exhibited the ability to form intrachain disulfide linkage with Cys25. Moreover, Cys10 and Cys40 played a functionally important role in maintaining the structural and conformational stability and high surface hydrophobicity of the N-terminal domain of HMW-GS, which in turn facilitated the formation of HMW polymers and massive disulfide linkage of HMW-GS through hydrophobic interaction. Additionally, the 1Dx5-N mutants in which Cys were replaced by serine (Ser) presented different effects on dough functionality, while only the C25S mutant produced positive effects compared with wild type 1Dx5-N. Na2CO3-induced β-elimination of cystine might occur in glutenin without heating, which would make it much easier to reduce the nutritional quality of flour products by the cost of lysine. Therefore, these results give a deep understanding of the disulfide linkage of the N-terminal domain of HMW-GS and its functional importance, which will provide a practical guide to effectively generate a superior HMW-GS allele by artificial mutagenesis.

  10. 芽孢杆菌R1共培养对嗜水气单胞菌NJ-1毒力基因表达的影响%Effects of coculture of Bacillus sp.R1 and Aeromonas hydrophila NJ-1 on the virulent factor gene expression of NJ-1

    Institute of Scientific and Technical Information of China (English)

    何夙旭; 王全民; 黄路; 周志刚

    2016-01-01

    为探讨芽孢杆菌潜在的淬灭靶点,本研究通过芽孢杆菌R1与嗜水气单胞菌NJ-1共培养,并对N J-1生物量、信号分子产生量、毒力因子基因和群体感应(QS)关键调控基因表达量进行检测.结果显示:①N J-1单独培养时,信号分子BHL和HHL的产量与NJ-1生长趋势一致,在27 h时达到峰值并启动LuxR表达,进而调控毒力因子金属蛋白酶、丝氨酸蛋白酶、肠毒素、气溶素和血溶素等表达,其在27~30 h时呈现峰值表达,通路QseB在27~30 h启动表达,48 h时达到峰值,而种间调控LuxS基因表达一直处于低水平状态;②与芽孢杆菌R1共培养时,仅痕量AHLs信号分子被检出,毒力因子相关基因表达量均显著下调;LuxR表达受抑制,LuxS在36h时表达量显著上调,未影响QseB正常表达;③AHLs与R1共培养可被显著降解.研究表明,芽孢杆菌R1抑制NJ-1毒力因子相关基因表达可能与其对NJ-1多QS系统进行调控相关联.

  11. Address Points, Address points, primarily derived from property tax records. Statewide coverage for NJ, but some addresses missing, particularly those where multiple addresses exist on a single parcel., Published in 2016, 1:2400 (1in=200ft) scale, NJ Office of GIS.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Address Points dataset, published at 1:2400 (1in=200ft) scale, was produced all or in part from Other information as of 2016. The source is NJ Office of GIS. It...

  12. Expression and enzymatic characterization of a cold-adapted β-agarase from Antarctic bacterium Pseudoalteromonas sp. NJ21

    Science.gov (United States)

    Li, Jiang; Sha, Yujie

    2015-03-01

    An agar-degrading bacterium, designated as Pseudoalteromonas sp. NJ21, was isolated from an Antarctic sediment sample. The agarase gene aga1161 from Pseudoalteromonas sp. NJ21 consisting of a 2 382-bp coding region was cloned. The gene encodes a 793-amino acids protein and was found to possess characteristic features of the Glyco_hydro_42 family. The recombinant agarase (rAga1161) was overexpressed in Escherichia coli and purified as a fusion protein. Enzyme activity analysis revealed that the optimum temperature and pH for the purified recombinant agarase were 30-40°C and 8.0, respectively. rAga1161 was found to maintain as much as 80% of its maximum activity at 10°C, which is typical of a coldadapted enzyme. The pattern of agar hydrolysis demonstrated that the enzyme is an β-agarase, producing neoagarobiose (NA2) as the final main product. Furthermore, this work is the first proof of an agarolytic activity in Antarctic bacteria and these results indicate the potential for the Antarctic agarase as a catalyst in medicine, food and cosmetic industries.

  13. Vector similariton erbium-doped all-fiber laser generating sub-100-fs nJ pulses at 100 MHz.

    Science.gov (United States)

    Olivier, Michel; Piché, Michel

    2016-02-08

    Erbium-doped mode-locked fiber lasers with repetition rates comparable to those of solid-state lasers and generating nJ pulses are required for many applications. Our goal was to design a fiber laser that would meet such requirements, that could be built at relatively low cost and that would be reliable and robust. We thus developed a high-fundamental-repetition-rate erbium-doped all-fiber laser operating in the amplifier similariton regime. Experimental characterization shows that this laser, which is mode-locked by nonlinear polarization evolution, emits 76-fs pulses with an energy of 1.17 nJ at a repetition rate of 100 MHz. Numerical simulations support the interpretation of self-similar evolution of the pulse in the gain fiber. More specifically we introduce the concept of vector similariton in fiber lasers. The coupled x- and y- polarization components of such a pulse have a pulse profile with a linear chirp and their combined power profile evolves self-similarly when the nonlinear asymptotic regime is reached in the gain fiber.

  14. Zebrafish cyclin Dx is required for development of motor neuron progenitors, and its expression is regulated by hypoxia-inducible factor 2α.

    Science.gov (United States)

    Lien, Huang-Wei; Yuan, Rey-Yue; Chou, Chih-Ming; Chen, Yi-Chung; Hung, Chin-Chun; Hu, Chin-Hwa; Hwang, Sheng-Ping L; Hwang, Pung-Pung; Shen, Chia-Ning; Chen, Chih-Lung; Cheng, Chia-Hsiung; Huang, Chang-Jen

    2016-06-21

    Cyclins play a central role in cell-cycle regulation; in mammals, the D family of cyclins consists of cyclin D1, D2, and D3. In Xenopus, only homologs of cyclins D1 and D2 have been reported, while a novel cyclin, cyclin Dx (ccndx), was found to be required for the maintenance of motor neuron progenitors during embryogenesis. It remains unknown whether zebrafish possess cyclin D3 or cyclin Dx. In this study, we identified a zebrafish ccndx gene encoding a protein which can form a complex with Cdk4. Through whole-mount in situ hybridization, we observed that zccndx mRNA is expressed in the motor neurons of hindbrain and spinal cord during development. Analysis of a 4-kb promoter sequence of the zccndx gene revealed the presence of HRE sites, which can be regulated by HIF2α. Morpholino knockdown of zebrafish Hif2α and cyclin Dx resulted in the abolishment of isl1 and oligo2 expression in the precursors of motor neurons, and also disrupted axon growth. Overexpression of cyclin Dx mRNA in Hif2α morphants partially rescued zccndx expression. Taken together, our data indicate that zebrafish cyclin Dx plays a role in maintaining the precursors of motor neurons.

  15. DX200发射机OMC输出网络的分析与维护

    Institute of Scientific and Technical Information of China (English)

    崔德刚

    2012-01-01

    DX200发射机的OMC输出匹配网络由带通滤波器和反Γ网络两部分组成。带通滤波器具有滤波和阻抗匹配的双重功能;反Γ网络通过阻抗变换将功率合成器的输出阻抗与馈线阻抗相匹配。本文结合OMC网络的基本原理,详细介绍了OMC输出网络的技术改造的过程。对于维护好OMC网络,提高OMC网络工作的安全性能,保证发射机能够稳定、可靠的运行具有十分重要的意义。

  16. The statistical analysis of failure of a MEVATRON77 DX67 linear accelerator over a ten year period

    CERN Document Server

    Aoyama, H; Tahara, S; Uno, H; Kadohisa, S; Azuma, Y; Nakagiri, Y; Hiraki, Y

    2003-01-01

    A linear accelerator (linac) takes a leading role in radiation therapy. A linac consists of complicated main parts and systems and it is required that highly accurate operational procedures should be maintained. Operational failure occurs for various reasons. In this report, the failure occurrences of one linac over a ten year period were recorded and analyzed. The subject model was a MEVATRON77 DX67 (Siemens, Inc). The failure rate for each system, the form classification of the contents of failure, the operation situation at the time of failure, and the average performance life of the main parts were totaled. Moreover, the relation between the number of therapies that patients received (operating efficiency) and the failure rate within that number and the relation between environment (temperature and humidity) and the failure rate attributed to other systems were analyzed. In this report, irradiation interruption was also included with situations where treatment was unable to begin in total for the number o...

  17. Effect of next-nearest-neighbour interaction on $d_{x^{2}−y^{2}}$ -wave superconducting phase in 2D t-J model

    Indian Academy of Sciences (India)

    N S Mondal; N K Ghosh

    2010-01-01

    n exact diagonalization calculation of the t-J model on 2D square cluster has been studied for the ground state properties of HTSC. Effect of next-nearest-neighbour hopping and magnetic (both antiferromagnetic and ferromagnetic) interaction on $d_{x^{2} −y^{2}}$-wave pairing has been shown. Relative strength of the next-nearest-neighbour interaction with respect to that of near-neighbour interaction for the strongest $d_{x^{2} −y^{2}}$-wave pairing has been estimated. A schematic phase diagram is shown. It is shown that a two-sublattice model with antiferromagnetic interaction between them and a small intra-ferromagnetic-type interaction in one sublattice favours $d_{x^{2} −y^{2}}$-wave superconductivity and moderate negative type NNN hopping adds flavours to this phase.

  18. Heterogeneity of the M1 muscarinic receptor subtype between peripheral lung and cerebral cortex demonstrated by the selective antagonist AF-DX 116

    Energy Technology Data Exchange (ETDEWEB)

    Bloom, J.W.; Halonen, M.; Seaver, N.A.; Yamamura, H.I.

    1987-07-27

    Recent studies have demonstrated that the majority of muscarinic receptors in rabbit peripheral lung homogenates bind pirenzepine with high affinity (putative M1 subtype). In experiments of AF-DX 116 inhibiting (TH)(-)quinuclidinyl benzilate or (TH)pirenzepine, the authors found similar inhibitory constants for AF-DX 116 binding in rat heart and rabbit peripheral lung that were 4-fold smaller (i.e. of higher affinity) than the inhibitory constant for rat cerebral cortex. This results demonstrates heterogeneity of the M1 muscarinic receptor subtype between peripheral lung and cerebral cortex. 20 references, 1 figure, 2 tables.

  19. Clock Circuit Analysis of DX200 Medium Wave Transmitter's Control Board%DX200中波发射机控制板卡时钟电路解析

    Institute of Scientific and Technical Information of China (English)

    余芳

    2016-01-01

    DX200 medium wave transmitter's control board has a stepping sequence control function when the transmitter starts. Also it monitors the power amplifier unit and gives protective response to the faults of internal and external parts, etc. In order to make every control circuit coordinately work on time, we have adopted a 555 in-tegrated timer which constitutes an astable free-running multivibrator with peripheral resistance and capacitance. The multivibrator generates an 8 KHZ clock signal. Frequency divider made with 74 hc161 synchronous counting units produces 4 KHZ, 128 HZ, 64 HZ, 16 HZ and 1/64 HZ, sends them to each PAL and programmable logic de-vices, and then provides corresponding control. Based on 555 integrated timer and 74 hc161 synchronous counter, the paper introduces in detail the structure and internal principle and their functions, and elaborates the generating principle of the transmitter control board's clock circuit.%DX200中波发射机控制板为发射机提供开机时步进起动的顺序控制,还对功放单元进行监视,对内部外部的故障情况进行保护性响应等,为了使各个部分控制电路在时间上能够协调的工作,我们采用一只555集成定时器与外围电阻、电容构成一个无稳态自激多谐振荡器,使其产生8KHZ的时钟信号。利用74HC161同步计数机组成分频器产生的4kHz,128Hz,64Hz,16Hz,1/64Hz发送到每个PAL和可编程逻辑器件,提供相应的控制。本文详细介绍了555集成定时器和74HC161同步计数器的结构组成、内部原理及其功能,阐述了发射机控制板卡时钟电路产生的原理。

  20. Strategies for bird conservation: The Partners in Flight planning process; Proceedings of the 3rd Partners in Flight Workshop; 1995 October 1-5; Cape May, NJ

    Science.gov (United States)

    Rick Bonney; David N. Pashley; Robert J. Cooper; Larry Niles

    2000-01-01

    This volume represents a compilation of papers presented at the 3rd International Partners in Flight Workshop held October 1-5, 1995, at the Grand Hotel in Cape May, NJ. The title of the workshop was "Partners in Flight Conservation Plan: Building Consensus for Action." Manuscripts have been available on-line at the Cornell Laboratory of Ornithology web site...

  1. Northern Saw-whet Owls (Aegolius acadicus) captured at Cape May Point, NJ, 1980-1994: comparison of two capture techniques

    Science.gov (United States)

    Katharine E. Duffy; Patrick E. Matheny

    1997-01-01

    During autumn migration 1980-1994, 1,270 Northern Saw-whet Owls (Aegolius acadicus) (NSWO) were captured and banded at Cape May Point, NJ. From 1980-1988, captures were effected by passive mist-netting. From 1989-1994, an audiolure (NSWO territorial song broadcast loudly from dusk to dawn in the trapping area) was used to enhance capture rate. 638...

  2. 76 FR 4284 - Foreign-Trade Zone 49-Newark, NJ Area; Application for Subzone; LVMH Watch & Jewelry U.S.A., Inc...

    Science.gov (United States)

    2011-01-25

    ... & Jewelry U.S.A., Inc. (Watches, Jewelry Products and Leather Goods); Springfield, NJ An application has... LVMH Watch & Jewelry U.S.A., Inc. (LVMH), located in Springfield, New Jersey. The application was..., jewelry products, leather goods (apparel, hand bags, wallets, cases), accessories, and luggage. All of...

  3. A 158 fs 5.3 nJ fiber-laser system at 1 mu m using photonic bandgap fibers for dispersion control and pulse compression

    DEFF Research Database (Denmark)

    Nielsen, C.K.; Jespersen, Kim Giessmann; Keiding, S.R.

    2006-01-01

    We demonstrate a 158 fs 5.3 nJ mode-locked laser system based on a fiber oscillator, fiber amplifier and fiber compressor. Dispersion compensation in the fiber oscillator was obtained with a solid-core photonic bandgap (SC-PBG) fiber spliced to standard fibers, and external compression is obtaine...

  4. High concordance between two companion diagnostics tests: a concordance study between the HercepTest and the HER2 FISH pharmDx kit

    DEFF Research Database (Denmark)

    Jørgensen, Jan Trøst; Møller, Susanne; Rasmussen, Birgitte;

    2011-01-01

    The present study was done to investigate the concordance between the HER2 status measured by immunohistochemical analysis (HercepTest, DAKO, Carpinteria, CA) and fluorescence in situ hybridization (FISH; HER2 FISH pharmDx, DAKO) in a large study cohort (n = 681) of patients with high-risk breast...

  5. An in-situ neutron diffraction study of the ageing of CaNi5Dx at 80ºC and 9 bar

    DEFF Research Database (Denmark)

    Pitt, M.P.; Brinks, H.W.; Jensen, Jens Oluf;

    2004-01-01

    The intrinsic ageing of the CaNi5Dx system has been studied at 80 ◦C and 9 bar over a period of 13 days. The system displays a distinct two-phase mixture of the intermediate and phases, whose phase proportions approach 40 and 50 wt.%, respectively at the end of the ageing period. The change in pr...

  6. Effects of the large gluon polarization on $xg_1^d(x)$ and J/$\\psi$ productions at polarized ep and pp collisions

    CERN Document Server

    Morii, T; Yamanishi, T

    1994-01-01

    The recent SMC data of $xg_1^d(x)$ are reproduced with the large polarized gluons. To study further the polarized gluon distribution in a proton, we calculate the spin--dependent differential cross section for J/$\\psi$ leptoproductions and the two--spin asymmetry for J/$\\psi$ hadroproductions. Its experimental implication is discussed.

  7. Exploring metal effects and synergistic interactions of ferric stimulation on azo-dye decolorization by new indigenous Acinetobacter guillouiae Ax-9 and Rahnella aquatilis DX2b.

    Science.gov (United States)

    Ng, I-Son; Xu, Fangxin; Ye, Chiming; Chen, Bor-Yann; Lu, Yinghua

    2014-02-01

    The first-attempt study deciphered metal-interacting effects on dye-decolorizing capabilities of indigenous bioelectricity-generating strains, Acinetobacter guillouiae Ax-9 and Rahnella aquatilis DX2b. Most of the metallic ions were inhibitory to color removal capabilities of these strains. However, with supplementation of 5 mM ferric chloride, specific decolorization rate (SDR) of Ax-9 increased by 55.48% compared to Fe(3+)-free conditions. In contrast, SDR of DX2b decreased 75.35% due to the inhibition of ferric chloride. On the other hand, ferric citrate could stimulate SDR of DX2b for 21.5% at same dosage. Enzymatic assay indicated that Fe reductase activity was consistent with synergistic effects of ferric chloride on Ax-9, and ferric citrate on DX2b. Protein analysis via SDS-PAGE and identification of Tandem MS/MS afterwards showed that outer membrane protein (Omp) primarily deals with decolorization as a channeling regulation. Moreover, molecular modeling and bioinformatics data also provided detailed evidences to confirm the biological significance of Omp.

  8. Screened Raman response in two-dimensional d(x2-y2)-wave superconductors: Relative intensities in different symmetry channels

    DEFF Research Database (Denmark)

    Wenger, F.; Käll, M.

    1997-01-01

    We analyze the Raman-scattering response in a two-dimensional d(x2-y2)-wave superconductor and point out a strong suppression of relative intensity in the screened A(1g) channel compared to the B-1g channel for a generic tight-binding model. This is in contrast with the observed behavior in high...

  9. 2dx_automator: implementation of a semiautomatic high-throughput high-resolution cryo-electron crystallography pipeline.

    Science.gov (United States)

    Scherer, Sebastian; Kowal, Julia; Chami, Mohamed; Dandey, Venkata; Arheit, Marcel; Ringler, Philippe; Stahlberg, Henning

    2014-05-01

    The introduction of direct electron detectors (DED) to cryo-electron microscopy has tremendously increased the signal-to-noise ratio (SNR) and quality of the recorded images. We discuss the optimal use of DEDs for cryo-electron crystallography, introduce a new automatic image processing pipeline, and demonstrate the vast improvement in the resolution achieved by the use of both together, especially for highly tilted samples. The new processing pipeline (now included in the software package 2dx) exploits the high SNR and frame readout frequency of DEDs to automatically correct for beam-induced sample movement, and reliably processes individual crystal images without human interaction as data are being acquired. A new graphical user interface (GUI) condenses all information required for quality assessment in one window, allowing the imaging conditions to be verified and adjusted during the data collection session. With this new pipeline an automatically generated unit cell projection map of each recorded 2D crystal is available less than 5 min after the image was recorded. The entire processing procedure yielded a three-dimensional reconstruction of the 2D-crystallized ion-channel membrane protein MloK1 with a much-improved resolution of 5Å in-plane and 7Å in the z-direction, within 2 days of data acquisition and simultaneous processing. The results obtained are superior to those delivered by conventional photographic film-based methodology of the same sample, and demonstrate the importance of drift-correction.

  10. The Berry-Keating operator on L{sup 2}(R{sub >},dx) and on compact quantum graphs with general self-adjoint realizations

    Energy Technology Data Exchange (ETDEWEB)

    Endres, Sebastian; Steiner, Frank, E-mail: sebastian.endres@uni-ulm.d, E-mail: frank.steiner@uni-ulm.d [Institut fuer Theoretische Physik, Universitaet Ulm Albert-Einstein-Allee 11, 89081 Ulm (Germany)

    2010-03-05

    The Berry-Keating operator H{sub BK} := -i h-bar (x d/dx + 1/2) (Berry and Keating 1999 SIAM Rev. 41 236) governing the Schroedinger dynamics is discussed in the Hilbert space L{sup 2}(R{sub >},dx) and on compact quantum graphs. It has been proved that the spectrum of H{sub BK} defined on L{sup 2}(R{sub >},dx) is purely continuous and thus this quantization of H{sub BK} cannot yield the hypothetical Hilbert-Polya operator possessing as eigenvalues the nontrivial zeros of the Riemann zeta function. A complete classification of all self-adjoint extensions of H{sub BK} acting on compact quantum graphs is given together with the corresponding secular equation in form of a determinant whose zeros determine the discrete spectrum of H{sub BK}. In addition, an exact trace formula and the Weyl asymptotics of the eigenvalue counting function are derived. Furthermore, we introduce the 'squared' Berry-Keating operator H{sub BK}{sup 2} := -x{sup 2} d{sup 2}/dx{sup 2} -2x d/dx - 1/4 which is a special case of the Black-Scholes operator used in financial theory of option pricing. Again, all self-adjoint extensions, the corresponding secular equation, the trace formula and the Weyl asymptotics are derived for H{sup 2}{sub BK} on compact quantum graphs. While the spectra of both H{sub BK} and H{sup 2}{sub BK} on any compact quantum graph are discrete, their Weyl asymptotics demonstrate that neither H{sub BK} nor H{sup 2}{sub BK} can yield as eigenvalues the nontrivial Riemann zeros. Some simple examples are worked out in detail.

  11. Focalyx Dx, Bx, Tx et Apps: A novel contemporary fusion paradigm for the management of prostate cancer.

    Science.gov (United States)

    Bianco, F J; Martínez-Salamanca, J I

    2016-07-01

    FocalyxTM conceived as a response to emerging evidence data across numerous cancer lesions that questions current standard treatment approaches that too often lead to detrimental quality of life yet delivering limited survival benefit, especially in-lieu of advances in imaging technology applicable to cancer patients. The Focalyx paradigm aims to control cancer with improvement in quality of life. We initially devised 5 milestones: 1- Consistently optimize Prostate MRI imaging using the novel published protocols adopted as guidelines by societies such as the European Society of Urology and Radiology; 2- Evaluate fusion platform software solutions that existed; 3- Determine best fusión platform for Focalyx on practicality, precision, and workflow premises; 4- Evaluate commercially available FDA approved ablative technologies to implement our treatment vision; 5- Design a treatment option that can be performed in the office setting under local anesthesia, which would not impact negatively QOL outcomes of Prostate Cancer patients and seamless constant nonintrusive practical patient-physician interaction by the Focalyx app that facilitates follow up and provides early warning signals shall any change in the disease dynamics emerge. Prostate cancer was identified as the pilot disease for Focalyx to deliver a "GPS" like solution for the prostate gland that destroys identifiable disease without adverse effects such as: cancer anxiety, urinary incontinence, loss of erections and ejaculation. Since September of 2013, over 300 men have been accrued in NCT02381990- clintrials.gov evaluating the feasibility of our solutions for imaging (FocalyxDx), Biopsy (FocalyxBx) and Treatment (FocalyxTx). In this review we detail the tools available to achieve the Focalyx paradigm for men with Prostate Cancer.

  12. Differential Insulin Secretion of High-Fat Diet-Fed C57BL/6NN and C57BL/6NJ Mice: Implications of Mixed Genetic Background in Metabolic Studies.

    Directory of Open Access Journals (Sweden)

    Camille Attané

    Full Text Available Many metabolic studies employ tissue-specific gene knockout mice, which requires breeding of floxed gene mice, available mostly on C57BL/6N (NN genetic background, with cre or Flp recombinase-expressing mice, available on C57BL/6J (JJ background, resulting in the generation of mixed C57BL/6NJ (NJ genetic background mice. Recent awareness of many genetic differences between NN and JJ strains including the deletion of nicotinamide nucleotide transhydrogenase (nnt, necessitates examination of the consequence of mixed NJ background on glucose tolerance, beta cell function and other metabolic parameters. Male mice with NN and NJ genetic background were fed with normal or high fat diets (HFD for 12 weeks and glucose and insulin homeostasis were studied. Genotype had no effect on body weight and food intake in mice fed normal or high fat diets. Insulinemia in the fed and fasted states and after a glucose challenge was lower in HFD-fed NJ mice, even though their glycemia and insulin sensitivity were similar to NN mice. NJ mice showed mild glucose intolerance. Moreover, glucose- but not KCl-stimulated insulin secretion in isolated islets was decreased in HFD-fed NJ vs NN mice without changes in insulin content and beta cell mass. Under normal diet, besides reduced fed insulinemia, NN and NJ mice presented similar metabolic parameters. However, HFD-fed NJ mice displayed lower fed and fasted insulinemia and glucose-induced insulin secretion in vivo and ex vivo, as compared to NN mice. These results strongly caution against using unmatched mixed genetic background C57BL/6 mice for comparisons, particularly under HFD conditions.

  13. Novel Approach for Isolation and Identification of Porcine Epidemic Diarrhea Virus (PEDV) Strain NJ Using Porcine Intestinal Epithelial Cells

    Science.gov (United States)

    Shi, Wen; Jia, Shuo; Zhao, Haiyuan; Yin, Jiyuan; Wang, Xiaona; Yu, Meiling; Ma, Sunting; Wu, Yang; Chen, Ying; Fan, Wenlu; Xu, Yigang; Li, Yijing

    2017-01-01

    Porcine epidemic diarrhea virus (PEDV), which is the causative agent of porcine epidemic diarrhea in China and other countries, is responsible for serious economic losses in the pork industry. Inactivated PEDV vaccine plays a key role in controlling the prevalence of PEDV. However, consistently low viral titers are obtained during the propagation of PEDV in vitro; this represents a challenge to molecular analyses of the virus and vaccine development. In this study, we successfully isolated a PEDV isolate (strain NJ) from clinical samples collected during a recent outbreak of diarrhea in piglets in China, using porcine intestinal epithelial cells (IEC). We found that the isolate was better adapted to growth in IECs than in Vero cells, and the titer of the IEC cultures was 104.5 TCID50/0.1 mL at passage 45. Mutations in the S protein increased with the viral passage and the mutations tended towards attenuation. Viral challenge showed that the survival of IEC-adapted cultures was higher at the 45th passage than at the 5th passage. The use of IECs to isolate and propagate PEDV provides an effective approach for laboratory-based diagnosis of PEDV, as well as studies of the epidemiological characteristics and molecular biology of this virus. PMID:28117718

  14. The c—Axis Infrared Conductivity of a dx2—y2— Wave Superconductor with the Hopping Assisted by the Spin Fluctuations

    Institute of Scientific and Technical Information of China (English)

    LOUPing; CAOLie-Zhao; 等

    2002-01-01

    A theory of the c-axis infrared conductivity of a dx2-y2- wave superconductor due to the competition between the interlayer direct hopping and the hopping assisted by the spin fluctuations has been developed.The prediction of our theory captures the main feature of the experiment.Thus we argue that the anomalous behavior of the c-axis infrared conductivity of the underdoped cuprates in superconducting state may be properly understood within the theory.

  15. The New Aptima HCV Quant Dx Real-time TMA Assay Accurately Quantifies Hepatitis C Virus Genotype 1-6 RNA.

    Science.gov (United States)

    Chevaliez, Stéphane; Dubernet, Fabienne; Dauvillier, Claude; Hézode, Christophe; Pawlotsky, Jean-Michel

    2017-06-01

    Sensitive and accurate hepatitis C virus (HCV) RNA detection and quantification is essential for the management of chronic hepatitis C therapy. Currently available platforms and assays are usually batched and require at least 5hours of work to complete the analyses. The aim of this study was to evaluate the ability of the newly developed Aptima HCV Quant Dx assay that eliminates the need for batch processing and automates all aspects of nucleic acid testing in a single step, to accurately detect and quantify HCV RNA in a large series of patients infected with different HCV genotypes. The limit of detection was estimated to be 2.3 IU/mL. The specificity of the assay was 98.6% (95% confidence interval: 96.1%-99.5%). Intra-assay and inter-assay coefficients of variation ranged from 0.09% to 5.61%, and 1.05% to 3.65%, respectively. The study of serum specimens from patients infected with HCV genotypes 1 to 6 showed a satisfactory relationship between HCV RNA levels measured by the Aptima HCV Quant Dx assay, and both real-time PCR comparators (Abbott RealTime HCV and Cobas AmpliPrep/Cobas TaqMan HCV Test, version 2.0, assays). the new Aptima HCV Quant Dx assay is rapid, sensitive, reasonably specific and reproducible and accurately quantifies HCV RNA in serum samples from patients with chronic HCV infection, including patients on antiviral treatment. The Aptima HCV Quant Dx assay can thus be confidently used to detect and quantify HCV RNA in both clinical trials with new anti-HCV drugs and clinical practice in Europe and the US. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Automated tubule nuclei quantification and correlation with oncotype DX risk categories in ER+ breast cancer whole slide images

    Science.gov (United States)

    Romo-Bucheli, David; Janowczyk, Andrew; Romero, Eduardo; Gilmore, Hannah; Madabhushi, Anant

    2016-03-01

    Early stage estrogen receptor positive (ER+) breast cancer (BCa) treatment is based on the presumed aggressiveness and likelihood of cancer recurrence. The primary conundrum in treatment and management of early stage ER+ BCa is identifying which of these cancers are candidates for adjuvant chemotherapy and which patients will respond to hormonal therapy alone. This decision could spare some patients the inherent toxicity associated with adjuvant chemotherapy. Oncotype DX (ODX) and other gene expression tests have allowed for distinguishing the more aggressive ER+ BCa requiring adjuvant chemotherapy from the less aggressive cancers benefiting from hormonal therapy alone. However these gene expression tests tend to be expensive, tissue destructive and require physical shipping of tissue blocks for the test to be done. Interestingly breast cancer grade in these tumors has been shown to be highly correlated with the ODX risk score. Unfortunately studies have shown that Bloom-Richardson (BR) grade determined by pathologists can be highly variable. One of the constituent categories in BR grading is the quantification of tubules. The goal of this study was to develop a deep learning neural network classifier to automatically identify tubule nuclei from whole slide images (WSI) of ER+ BCa, the hypothesis being that the ratio of tubule nuclei to overall number of nuclei would correlate with the corresponding ODX risk categories. The performance of the tubule nuclei deep learning strategy was evaluated with a set of 61 high power fields. Under a 5-fold cross-validation, the average precision and recall measures were 0:72 and 0:56 respectively. In addition, the correlation with the ODX risk score was assessed in a set of 7513 high power fields extracted from 174 WSI, each from a different patient (At most 50 high power fields per patient study were used). The ratio between the number of tubule and non-tubule nuclei was computed for each WSI. The results suggests that for BCa

  17. Generation of a 2.2 nJ picosecond optical pulse with blue-violet wavelength using a GaInN master oscillator power amplifier

    Science.gov (United States)

    Koda, Rintaro; Takiguchi, Yoshiro; Kono, Shunsuke; Watanabe, Hideki; Hanzawa, Yasunari; Nakajima, Hiroshi; Shiozaki, Masaki; Sugawara, Nobuhiro; Kuramoto, Masaru; Narui, Hironobu

    2015-07-01

    We report the generation of a picosecond optical pulse with 2.2 nJ pulse energy at blue-violet wavelengths using a GaN-based mode-locked laser diode (MLLD) and a semiconductor optical amplifier (SOA). The picosecond optical pulse generated by MLLD at a frequency of 812 MHz was amplified effectively by SOA. We optimized SOA with a widely flared waveguide structure to generate a high optical pulse energy.

  18. Effect of metal ions on fermentation and metabolization of Actinobacillus Succinogenes NJ113%金属离子对产琥珀酸放线杆菌NJ113厌氧发酵代谢的影响

    Institute of Scientific and Technical Information of China (English)

    郑晓宇; 李建; 方晓江; 陈可泉; 奚永兰; 姜岷

    2011-01-01

    The effects of adding Mg2+. Mn2+, Co2+ on cell growth and succinic acid production was investigated. The metabolic flux of Actinobacillus succinogenes NJ113 was calculated. It was found that the flux of HMP increased by 445.38%, 176.23 % and 171.67% after adding 6 mmol/L Mg2+, 6 mmol/L Mn2+, 2 mmol/L Co2+ respectively, thus the reducing power was better balanced. The flux of C4 was 57.70%, 15.94% and 2.91% higher respectively, which led to the improvement of succinic acid flux by 62.69%, 18.91% and 5.01%. The key enzyme activity analysis showed that the specific activity of PEP carboxykinase (Pck) reached 568.732 U/mg, 728.049 U/mg and 339.686 U/mg with 6 mmol/L Mg2+, 6 mmol/L Mn2+, 2 mmol/L Co2+ addition respectively. As a result, the concentration of succinc acid was 27.83 g/L, 26.27 g/L, and 23.54 g/L, while the concentration of control was only 22.79 g/L.%考察了培养基中分别添加Mg2+、Mn2+、Co2+3种金属离子对Actinobacilus Succinogenes NJ113菌体生长及产酸的影响,并进行了代谢通量分析。结果表明培养基中分别添加6mmTo1/LMg2+、6mmol/LMnz+、2mmol/LCo2+后流向HMP途径的通量r17比对照组分别提高了445.38%、176.23%和171.67%,使得还原力不足的矛盾得到缓解;流向C4途径的通量r13比对照组分别提高了57.70%、15.94%和2.91%;最终使得流向丁二酸的通量r16比对照组分别提高了62.69%、18.91%和5.01%。此外,关键酶活分析结果显示分别添加Mg2+、Mn2+以及Co2+后,PEP羧化激酶(Pck)比活力由对照组的339.18U/mg分别提高到568.732U/mg、728.049U/mg和339.686U/mg。最终当培养基中分别添加6mmol/LMg2+、6immol/LMn2+、2immol/LCo2+后丁二酸产量分别为27.83 g/L、26.27 g/L和23.54 g/L,比对照的22.79 g/L分别提高22.11%、15.27%以及3.4%。

  19. Evaluation and correlation of risk recurrence in early breast cancer assessed by Oncotype DX(®), clinicopathological markers and tumor cell dissemination in the blood and bone marrow.

    Science.gov (United States)

    Aktas, Bahriye; Bankfalvi, Agnes; Heubner, Martin; Kimmig, Rainer; Kasimir-Bauer, Sabine

    2013-11-01

    The Oncotype DX(®) assay is a validated genomic test that predicts the likelihood of breast cancer recurrence, patient survival within ten years of diagnosis and the benefit of chemotherapy in early-stage, node-negative, estrogen receptor-positive breast cancer. Further markers of recurrence include disseminated tumor cells (DTCs) in the bone marrow (BM) and circulating tumor cells (CTCs) in the blood, particularly stemness-like tumor cells (slCTCs). In this study, Oncotype DX, DTCs, CTCs and slCTCs were used to evaluate the risk of recurrence in 68 patients with human epidermal growth factor receptor 2-negative, early-stage breast cancer. Formalin-fixed, paraffin-embedded tissue sections were analyzed for the expression of 16 cancer genes and 5 reference genes by Oncotype DX, yielding a recurrence score (RS). G2 tumors were evaluated for urokinase-type plasminogen activator (uPA)/plasminogen activator inhibitor type 1 (PAI1) and Ki-67. Two BM aspirates were analyzed by immunocytochemistry for DTCs using the pan-cytokeratin antibody A45-B/B3. CTCs and slCTCs in the blood were detected using the AdnaTest BreastCancer, AdnaTest EMT and the AdnaTest TumorStemCell. Oncotype DX was performed in 68 cases, yielding a low RS in 30/68 patients (44%), an intermediate RS in 29/68 patients (43%) and a high RS in 9/68 patients (13%). DTCs were detected in 19/68 patients (28%), CTCs in 13/68 patients (19%) and slCTCs in 26/68 (38%) patients. Moreover, 8/68 patients (12%) with G2 tumors were positive for uPA, 6/68 (9%) for PAI1 and 21/68 (31%) for Ki-67. Ki-67, progesterone receptor (PR) and G3 tumors were significantly correlated with RS (P<0.001; P=0.006; and P=0,002, respectively), whereas no correlation was identified between DTCs, CTCs, slCTCs and RS. Ki-67 may support therapeutic decisions in cases where Oncotype DX is not feasible. Larger patient cohorts are required to estimate the additional detection of DTCs and CTCs for the determination of risk recurrence.

  20. 甘蔗内生固氮菌Klebsiella variicola DX120E nifH基因的克隆与序列分析

    Institute of Scientific and Technical Information of China (English)

    张琨琨; 牛俊奇; 魏春燕; 邢永秀; 杨丽涛; 李杨瑞

    2014-01-01

    【目的】了解甘蔗内生固氮菌变栖克雷伯氏菌(Klebsiella variicola)DX120E nif H基因的生物信息学,为揭示甘蔗内生固氮菌DX120E的固氮分子机理提供理论依据。【方法】根据NCBI上其他固氮菌株的nif H序列设计引物,对内生固氮菌Klebsiella variicola DX120E菌进行PCR扩增;运用生物信息学方法对其核苷酸序列、编码的氨基酸序列进行分析,并对其蛋白结构进行预测。【结果】甘蔗内生固氮菌Klebsiella variicola DX120E nif H基因的ORF为882bp,Gen Bank登录号为KF732646.1,与Klebsiella pneumoniae 342、Klebsiella variicola At-22等6种固氮菌的nif H基因氨基酸序列同源性高达95.0%-99.0%。DX120E nifH蛋白与Klebsiella pneumoniae 342的亲缘关系最近,与非克雷伯氏菌固氮菌的亲缘关系较远。生物信息学分析显示,菌株DX120E的nif H基因编码293个氨基酸,起特别重要的氨基酸残基非常保守。该基因在N端有11个氨基酸残基即酪氨酸—甘氨酸—赖氨酸—甘氨酸—甘氨酸—异亮氨酸—甘氨酸—赖氨酸—丝氨酸—苏氨酸—苏氨酸,其属于典型结合ATP的基序结构。nif H蛋白分子量为32.07k D,pI为4.92,为酸性蛋白;其具有2个ASN糖基化位点,1个CAMP磷酸化位点,6个CK2磷酸化位点,6个PKC磷酸化位点。疏水性预测显示该蛋白为亲水性蛋白,无信号肽。【结论】变栖克雷伯氏菌(Klebsiella variicola)DX120E nif H基因的推导氨基酸序列与克雷伯氏菌固氮菌属具有较高的同源性,该基因在甘蔗生物固氮过程中可能起重要作用。

  1. Atmospheric dry deposition of trace elements measured around the urban and industrially impacted NY-NJ harbor

    Science.gov (United States)

    Yi, Seung-Muk; Totten, Lisa A.; Thota, Sathyapriya; Yan, Shu; Offenberg, John H.; Eisenreich, Steven J.; Graney, Joseph; Holsen, Thomas M.

    Long-term direct trace metal dry deposition measurements were made during 2001 and 2002 at two sites near the NY/NJ Harbor Estuary in New Jersey: Jersey City (JC) and New Brunswick (NB). In addition intensive dry deposition and atmospheric size distribution (ASD) measurements were made between September 2001 and June 2002. Dry deposition samples were obtained using modified MIC-B wet deposition samplers which deployed knife-edge surrogate surfaces during dry periods. ASDs were measured with micro-orifice uniform deposit impactors (MOUDI) and coarse particle rotary impactors (CPRI). The fluxes of trace metals were found to be highest at the JC site and lowest at the NB site. The dry deposition fluxes ranged from 0.030 (Cd) to 3800 (Al) μg m -2 d -1 and 0.14 (Cd) to 8100 (Al) μg m -2 d -1at NB and JC sites, respectively. Metals of crustal origin were found mostly in the coarse particle fraction and anthropogenic metals were found mostly in the fine particle fraction. For the intensive experiments, overall dry deposition velocities of several trace metals were determined by dividing measured fluxes by measured concentrations in different particle size ranges. For most of the elements, the flux was highly correlated with PM 10 and coarse particle concentrations. The overall dry deposition velocities of crustal elements (Al and Mg) varied from 3.7 to 8.7 cm s -1 with correlation coefficients ranging from 0.50 to 0.84. The best-fit dry deposition velocities for anthropogenic elements (Cr, Mn, Zn, and Pb; Cu, Mo, and Ba; V and Ni) varied more than those for crustal elements (0.52-25 vs. 3.7-8.7 cm s -1). The dry deposition velocities for most elements obtained using three size ranges were statistically significant with R2 values ranging from 0.37 to 0.84 except for V and Ni (0.12).

  2. A chronic high-cholesterol diet paradoxically suppresses hepatic CYP7A1 expression in FVB/NJ mice.

    Science.gov (United States)

    Henkel, Anne S; Anderson, Kristy A; Dewey, Amanda M; Kavesh, Mark H; Green, Richard M

    2011-02-01

    Cholesterol 7α-hydroxylase (CYP7A1) encodes for the rate-limiting step in the conversion of cholesterol to bile acids in the liver. In response to acute cholesterol feeding, mice upregulate CYP7A1 via stimulation of the liver X receptor (LXR) α. However, the effect of a chronic high-cholesterol diet on hepatic CYP7A1 expression in mice is unknown. We demonstrate that chronic cholesterol feeding (0.2% or 1.25% w/w cholesterol for 12 weeks) in FVB/NJ mice results in a >60% suppression of hepatic CYP7A1 expression associated with a >2-fold increase in hepatic cholesterol content. In contrast, acute cholesterol feeding induces a >3-fold upregulation of hepatic CYP7A1 expression. We show that chronic, but not acute, cholesterol feeding increases the expression of hepatic inflammatory cytokines, tumor necrosis factor (TNF)α, and interleukin (IL)-1β, which are known to suppress hepatic CYP7A1 expression. Chronic cholesterol feeding also results in activation of the mitogen activated protein (MAP) kinases, c-Jun N-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK). Furthermore, we demonstrate in vitro that suppression of CYP7A1 by TNFα and IL-1β is dependent on JNK and ERK signaling. We conclude that chronic high-cholesterol feeding suppresses CYP7A1 expression in mice. We propose that chronic cholesterol feeding induces inflammatory cytokine activation and liver damage, which leads to suppression of CYP7A1 via activation of JNK and ERK signaling pathways.

  3. Effects of Self-coiling of Organic Molecules on Intramolecular Exciplex Formation and Fluorescence Quenching in DX-H2O Solvent System

    Institute of Scientific and Technical Information of China (English)

    CHEN,Ying-Qi(陈英奇); WANG,Xiao-Zhong(王晓钟); JIANG,Xi-Kui(蒋锡夔); SHI,Ji-Liang(史济良); SHI,Min(施敏); LI,Zhan-Tmg(黎占亭)

    2002-01-01

    Effects of self-coiling of organic molecules on intramolecular exciplex formation of compound I, in which the carbazole chromophore and terephthalic acid methylester acceptor group are linked by one (CH2)10 chain, and the decrease of the fluorescence intensities of compounds H, Ⅲ, and Ⅳ, in which the carbazole chromophore and 3,5-dinitrobenzoate are connected by one aliphatic chain of (CH2)10 (Ⅱ), (CH2)12 (Ⅲ),or (CH2)4 (Ⅳ), have been studied in the dioxane(DX)-H2Obinary system. The results show that self-coiling of organic molecules in DX-H2O facilitates intramolecular exciplex formation of Ⅰ and induces the decrease of fluorescence intensities of Ⅱ, because of the proximity effect brought about by selfcoiling of organic molecules under hydrophobic-lipophilic interaction (HLI) between the excited carbazole chromophore and the acceptor. Since the similar effects are observed even when the concentrations of the probes are less than their CAgCs (critical aggregate concentratons) in the DX-H2Omixture withthe same φ values, formation of the intermolecular exciplex has been excluded. The effects are found to be strongly depended on φ values, indicating that they are mainly driven by HLI. The properties of the acceptors can also affect the intrmolecular exciplex formation. With terephthalic acid methylester moiety as the acceptor, the carbazole chromophore exihibits the fluorescence spectra of the exciplex,while with 3,5- dinitrobenzoate moiety as the acceptor, only the fluorescence spectra of excited carbazolyl chromphore are observed.

  4. Routine delayed voiding cystourethography after initial successful endoscopic treatment with Dextranomer/Hialuronic Acid Copolimer (Dx/HA) of vesicoureteral reflux (VUR). Is it necessary?

    Science.gov (United States)

    García-Aparicio, L; Blázquez-Gómez, E; Vila Santandreu, A; Camacho Diaz, J A; Vila-Cots, J; Ramos Cebrian, M; de Haro, I; Martin, O; Tarrado, X

    2016-12-01

    Some guidelines recommend an early voiding cystourethrography (VCUG) after endoscopic treatment of vesicoureteral reflux (VUR), but there's no consensus if it's necessary a long-term follow-up in these patients. The aim of our study is analyze if it's necessary a delayed VCUG after initial successful treatment with Dx/HA. We have reviewed all medical charts of patients that underwent Dx/HA treatment from 2006 to 2010. We have selected patients with initial successful treatment and more than 3 years of radiological and clinical follow-up. We have analyzed late clinical and radiological outcomes. One hundred and sixty children with 228 refluxing ureters underwent Dx/HA endoscopic treatment with a mean follow-up of 52.13 months. Early VCUG was performed in 215 ureters with an initial successful rate of 84.1%. The group of study was 94/215 ureters with more than 3 years of follow-up with a delayed VCUG. VUR was still resolved in 79,8% of the ureters. Clinical success rate was 91.7%. The incidence of febrile urinary tract infection in those patients with cured VUR and those with a relapsed VUR was 8 and 15%, respectively; but there were no significant differences. We have not found any variable related with relapsed VUR except those ureters that initially received 2 injections (P<.05). If our objective in the treatment of VUR is to reduce the incidence of febrile urinary tract infection it is not necessary to perform a delayed VCUG even though the long-term radiological outcomes is worse than clinical outcome. Copyright © 2016 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

  5. New structural and functional contexts of the Dx[DN]xDG linear motif: insights into evolution of calcium-binding proteins.

    Science.gov (United States)

    Rigden, Daniel J; Woodhead, Duncan D; Wong, Prudence W H; Galperin, Michael Y

    2011-01-01

    Binding of calcium ions (Ca²⁺) to proteins can have profound effects on their structure and function. Common roles of calcium binding include structure stabilization and regulation of activity. It is known that diverse families--EF-hands being one of at least twelve--use a Dx[DN]xDG linear motif to bind calcium in near-identical fashion. Here, four novel structural contexts for the motif are described. Existing experimental data for one of them, a thermophilic archaeal subtilisin, demonstrate for the first time a role for Dx[DN]xDG-bound calcium in protein folding. An integrin-like embedding of the motif in the blade of a β-propeller fold--here named the calcium blade--is discovered in structures of bacterial and fungal proteins. Furthermore, sensitive database searches suggest a common origin for the calcium blade in β-propeller structures of different sizes and a pan-kingdom distribution of these proteins. Factors favouring the multiple convergent evolution of the motif appear to include its general Asp-richness, the regular spacing of the Asp residues and the fact that change of Asp into Gly and vice versa can occur though a single nucleotide change. Among the known structural contexts for the Dx[DN]xDG motif, only the calcium blade and the EF-hand are currently found intracellularly in large numbers, perhaps because the higher extracellular concentration of Ca²⁺ allows for easier fixing of newly evolved motifs that have acquired useful functions. The analysis presented here will inform ongoing efforts toward prediction of similar calcium-binding motifs from sequence information alone.

  6. Inheritance and Expression of Copies of Transgenes 1Dx5 and 1Ax1 in Elite Wheat (Triticum aestivum L.) Varieties Transferred from Transgenic Wheat through Conventional Crossing

    Institute of Scientific and Technical Information of China (English)

    Sanhe LI; Ju LI; Nali WANG; Yuesheng WANG; Guangxiao YANG; Jingye FANG; Guangyuan HE

    2007-01-01

    To study the inheritance and expression of multiple copies of transgenes from transgenic wheat lines, three crosses between transgenic wheat lines B72-8-11b and B102-1-2 and Chinese elite wheat varieties Chuan89-107 and Emai 18 were carried out. Chuan89-107×B72-8-11b, Chuan89-107×B102-1-2 and Emai18×B72-8-11b, and F1 plants were selfed or backcrossed to obtain different generation populations.Protein analysis in grains of F1 and F2 and backcross progenies of BC1F1, BC1F2, BC1F3, BC2F1, BC2F2 and BC2F3 by sodium dodecyl sulfate-polyacrylamide gel electrophoresis showed that the transgenes 1Dx5 and 1Ax1 were expressed and segregated in the target wheat according to Mendelian laws. A range of 1Dx5 expression levels were observed in the progenies of Chuan89-107×B72-8-11b and Emai18×B72-8-11b, but the expression levels of 1Ax1 in progenies of Chuan89-107×B102-1-2 rarely changed. It suggested that the two foreign genes had different mechanisms of expression in the cross progeny, even though they were produced in the same way and the foreign 1Dx5 gene of 5-10 copies had the more complicated expression mechanism than the 1Ax1 gene of 4-5 copies.

  7. Differences between LASL- and ANL-processed cross sections. [MINX/1DX vs ETOE-2/MC/sup 2/-2

    Energy Technology Data Exchange (ETDEWEB)

    Kidman, R.B.; MacFarlane, R.E.; Becker, M.

    1978-03-01

    As part of the Los Alamos Scientific Laboratory (LASL) cross-section processing development, LASL cross sections and results from MINX/1DX system are compared to the Argonne National Laboratory cross sections and results from the ETOE-2/MC/sup 2/-2 system for a simple reactor problem. Exact perturbation theory is used to establish the eigenvalue effect of every isotope group cross-section difference. Cross sections, cross-section differences, and their eigenvalue effects are clearly and conveniently displayed and compared on a group-by-group basis.

  8. On the detection performance of semi-insulating GaAs detectors coupled to multichannel ASIC DX64 for X-ray imaging applications

    Energy Technology Data Exchange (ETDEWEB)

    Zat' ko, Bohumir [Institute of Electrical Engineering, Slovak Academy of Sciences, Dubravska cesta 9, SK-841 04 Bratislava (Slovakia)], E-mail: elekbzat@savba.sk; Dubecky, Frantisek [Institute of Electrical Engineering, Slovak Academy of Sciences, Dubravska cesta 9, SK-841 04 Bratislava (Slovakia); Scepko, Pavol [T and N System, Ltd., Severna 5, SK-974 01 Banska Bystrica (Slovakia); Grybos, Pawel [Department of Measurement and Instrumentation, AGH University of Science and Technology, Al. Mickiewicza 30, PL-30 059 Krakow (Poland); Mudron, Jan [MTC, a. s., Kuzmanyho 11, SK-031 01 Liptovsky Mikulas (Slovakia); Maj, Piotr; Szczygiel, Robert [Department of Measurement and Instrumentation, AGH University of Science and Technology, Al. Mickiewicza 30, PL-30 059 Krakow (Poland); Frollo, Ivan [Institute of Measurement Science, Slovak Academy of Sciences, Dubravska cesta 9, SK-841 04 Bratislava (Slovakia)

    2008-06-11

    Detectors based on semi-insulating (SI) GaAs show high detection efficiency and satisfactory energy resolution for modern X-ray digital imaging applications. This work deals with the performance of SI GaAs-based detectors coupled by wire bonding to the input of multichannel readout chip DX64 (technology CMOS 0.35 {mu}m). Detectors have circular Ti/Pt/Au multilayer Schottky blocking contacts with different diameters (0.75, 0.50, 0.30 and 0.20 mm). First results of operation of the used readout system in the single-photon counting regime are given.

  9. Extreme differentiation in single samples from the olivine-rich zone of the Palisades Sill, NY and NJ

    Science.gov (United States)

    Chau, K. X.; Sen, G.; Naslund, H. R.

    2007-12-01

    The Palisades Sill, NY and NJ, has long been the focus of much attention due to its potential contributions to the understanding of igneous differentiation. Many early authors, including N.L. Bowen, thought of the intrusion as an ideal example of crystal settling because of an olivine-rich zone that occurs close to the base of the sill. Later investigations demonstrated that at least three geochemically distinct batches of magma were emplaced at different levels within this body, one of which produced the olivine-rich zone. Here we report the results of our detailed electron probe study of 27 olivine grains, 134 plagioclase grains, and 181 pyroxene grains from four samples of the olivine-rich zone. In one of the rocks plagioclase ranges from An84 (large grain; core) to An0.5 (interstitial plagioclase), whereas olivine ranges from Fo81 - Fo69. These ranges are comparable to our other samples. The plagioclase range is far greater than what is shown by the Skaergaard (An25 - An69) and Bushveld (An30 - An80) intrusions. Though the sill has long been known to be vertically differentiated, such extreme differentiation in individual thumb-sized samples was not expected. The implication is that interstitial melt pockets were so well enclosed (i.e., zero permeability) by the surrounding crystals that they were sealed off from further communication with larger volumes of melt that may have existed at a higher levels in the sill at that time. That is, compaction and associated filter pressing was not efficient in removing the interstitial melt. It is unlikely that such a situation could occur if the olivine-rich zone formed early from a large body of magma because the load pressure of the overlying crystals and melt would be too great to avoid compaction. A better explanation is that the olivine-rich zone was emplaced as a separate magma batch (as suggested by several previous workers based on bulk rock geochemistry) in a mostly solidified magma-crystal mush. In this setting

  10. A chronic high-cholesterol diet paradoxically suppresses hepatic CYP7A1 expression in FVB/NJ mice[S

    OpenAIRE

    Henkel, Anne S.; Anderson, Kristy A.; Dewey, Amanda M.; Kavesh, Mark H.; Green, Richard M.

    2011-01-01

    Cholesterol 7α-hydroxylase (CYP7A1) encodes for the rate-limiting step in the conversion of cholesterol to bile acids in the liver. In response to acute cholesterol feeding, mice upregulate CYP7A1 via stimulation of the liver X receptor (LXR) α. However, the effect of a chronic high-cholesterol diet on hepatic CYP7A1 expression in mice is unknown. We demonstrate that chronic cholesterol feeding (0.2% or 1.25% w/w cholesterol for 12 weeks) in FVB/NJ mice results in a >60% suppression of hepati...

  11. 南极低温降解菌Shewanella sp. NJ49羟化酶分离纯化及最适产酶条件研究%Separation and purification of hydroxylase from Antarctic psychrophilic bacteriumShewanella sp. NJ49 and optimum conditions for its enzyme production

    Institute of Scientific and Technical Information of China (English)

    刘芳明; 王以斌; 曲长凤; 梁强; 郑洲; 缪锦来; 肖天

    2016-01-01

    Hydroxylase is a key enzyme with respect to bacteria during hydrocarbon degradation. In this paper, we investigate the Antarctic psychrophilic bacteriumShewanella sp. NJ49. To obtain a single component of hydroxy-lase, we separated and purified hydroxylase from NJ49 in a series of steps, i.e., ammonium sulfate precipitation, ultrafiltration concentration, and column chromatography with Sephadex G-75 as the column media. In addition, we studied the relationships between the activity of NJ49 hydroxylase and environmental factors such as temperature, pH, surfactant, and salinity. We found that purified hydroxylase comprised subunitsα,β, andγ, with estimated molecular masses of 56, 45, and 36 kD, respectively. The optimum conditions for producing NJ49 hydroxylase were a temperature of 15℃, a pH of 7.2, and a salinity of 55‰. Different types of surfactants had different effects on enzyme activity. Although individual amphoteric, cationic, and nonionic surfactants did not inhibit enzyme activity, a mixture of anionic and nonionic surfactants, as well as a mixture of cationic and nonionic surfactants, improved the activity of the hydroxylase.%羟化酶是细菌降解烷烃的关键酶,本文以南极低温降解菌Shewanella sp. NJ49为研究对象,通过硫酸铵沉淀、超滤浓缩及葡聚糖凝胶Sephadex G-75柱层析方法,分离纯化NJ49的羟化酶,获得了单一羟化酶组分,研究了温度、pH、表面活性剂和盐度等环境因素对 NJ49羟化酶酶活活性影响。结果表明,羟化酶组分由α、β、γ三个亚基组成,分子质量分别为56,45和36 kD。NJ49最适产酶条件为:温度15℃、pH7.2、盐度55;不同类型表面活性剂对酶的活性影响效应不一,两性离子表面活性剂、阳离子表面活性剂、非离子表面活性剂对酶活没有作用,阴离子表面活性剂+非离子表面活性剂混和剂和阳离子表面活性剂+非离子表面活性剂混和剂能提高羟化酶的活性。

  12. The JSpecView Project: an Open Source Java viewer and converter for JCAMP-DX, and XML spectral data files.

    Science.gov (United States)

    Lancashire, Robert J

    2007-12-07

    The JSpecView Open Source project began with the intention of providing both a teaching and research tool for the display of JCAMP-DX spectra. The development of the Java source code commenced under license in 2001 and was released as Open Source in March 2006. The scope was then broadened to take advantage of the XML initiative in Chemistry and routines to read and write AnIML and CMLspect documents were added.JSpecView has the ability to display the full range of JCAMP-DX formats and protocols and to display multiple spectra simultaneously. As an aid for the interpretation of spectra it was found useful to offer routines such that if any part of the spectral display is clicked, that region can be highlighted and the (x, y) coordinates returned. This is conveniently handled using calls from JavaScript and the feedback results can be used to initiate links to other applets like Jmol, to generate a peak table, or even to load audio clips providing helpful hints.Whilst the current user base is still small, there are a number of sites that already feature the applet. A tutorial video showing how to examine NMR spectra using JSpecView has appeared on YouTube and was formatted for replay on iPods and it has been incorporated into a chemistry search engine.

  13. The JSpecView Project: an Open Source Java viewer and converter for JCAMP-DX, and XML spectral data files

    Directory of Open Access Journals (Sweden)

    Lancashire Robert J

    2007-12-01

    Full Text Available Abstract The JSpecView Open Source project began with the intention of providing both a teaching and research tool for the display of JCAMP-DX spectra. The development of the Java source code commenced under license in 2001 and was released as Open Source in March 2006. The scope was then broadened to take advantage of the XML initiative in Chemistry and routines to read and write AnIML and CMLspect documents were added. JSpecView has the ability to display the full range of JCAMP-DX formats and protocols and to display multiple spectra simultaneously. As an aid for the interpretation of spectra it was found useful to offer routines such that if any part of the spectral display is clicked, that region can be highlighted and the (x, y coordinates returned. This is conveniently handled using calls from JavaScript and the feedback results can be used to initiate links to other applets like Jmol, to generate a peak table, or even to load audio clips providing helpful hints. Whilst the current user base is still small, there are a number of sites that already feature the applet. A tutorial video showing how to examine NMR spectra using JSpecView has appeared on YouTube and was formatted for replay on iPods and it has been incorporated into a chemistry search engine.

  14. Oncotype DX(®) colon cancer assay for prediction of recurrence risk in patients with stage II and III colon cancer: A review of the evidence.

    Science.gov (United States)

    You, Y Nancy; Rustin, Rudolph B; Sullivan, James D

    2015-06-01

    Advances in molecular biology have enabled identification of tumor biomarkers that allow for individualized risk assessment for patients with cancer. Molecular predictors of clinical outcome can help inform discussion regarding the role of adjuvant chemotherapy in patients with resected colon cancer, such as those with stage II colon cancer in which the benefit of adjuvant therapy is controversial or those with stage III colon cancer who may have a lower risk of recurrence and less absolute benefit from oxaliplatin therapy. This article summarizes the data surrounding the development, validation, and clinical and economic utility of the Oncotype DX(®) colon cancer assay, a multigene expression assay validated to independently predict recurrence risk in patients with stage II and III colon cancer beyond traditional factors.

  15. DX600型广播发射机中变频器的常见故障分析与判断方法

    Institute of Scientific and Technical Information of China (English)

    林日胜

    2015-01-01

    BALDOR ID15H401型交流—直流—交流变频器在DX600广播发射机冷却系统中起着非常重要的作用,在发射机的并机网络中使用,由于它处在系统的公共部分,所以它的故障往往造成较长时间的系统停机事故,维护人员如何及时快速有效的查找和排除故障,使发射机尽快恢复播出,减少停播时间,在实际应用中有着积极的意义。

  16. Nottingham-defined mitotic score: comparison with visual and image cytometric phosphohistone H3 labeling indices and correlation with Oncotype DX recurrence score.

    Science.gov (United States)

    Zbytek, Blazej; Cohen, Cynthia; Wang, Jason; Page, Andrew; Williams, Daron J; Adams, Amy L

    2013-01-01

    Prognosis of breast cancer patients has been determined traditionally by lymph node status, tumor size, and histologic grade. In recent years the Oncotype DX recurrence score (RS) assay has emerged as an expensive adjunct prognostic tool. Markers of proliferation play a large role in determination of RS, and we have shown previously that immunohistochemical expression of proliferation markers Ki-67 and phosphohistone H3 (PPH3) correlates with RS. Our current goal is comparison of the hematoxylin and eosin (H&E) mitotic score, defined by the Nottingham grading system, with anti-PPH3 mitotic figure labeling assessed by both visual and automated image analysis and correlation of mitotic score results with RS. Estrogen receptor-positive breast carcinomas from 137 patients with Oncotype DX testing were selected. A representative H&E-stained tumor section was evaluated. Mitoses were counted per 10 high-power fields and tumors graded using the Nottingham criteria by 1 pathologist in accordance with College of American Pathologists-recommended mitotic count cutoffs for a field diameter of 0.55 mm. An additional section was immunostained with PPH3 antibody. PPH3 mitotic scores were determined visually and by automated imaging system. Statistical analysis was performed using univariate tests and Spearman coefficient. There was a statistically significant positive correlation among the 3 methods of mitotic score assessment. Specifically, correlation of tumor grades obtained using visual and automated methods of assessment of mitotic activity with PPH3 stain was the strongest and most statistically significant (weighted κ value 0.84, P<0.001; Spearman coefficient 0.89, P<0.001). There was a statistically significant positive correlation between H&E mitosis score and RS (P<0.001, Spearman coefficient 0.30) and between visual PPH3 mitotic score and RS (P<0.001, Spearman coefficient 0.28). In conclusion, mitotic score by any of the 3 methods studied may be useful in assessing

  17. Establishment of a screening system for Tn5 insertion mutants of Bacillus pumilus DX01 with different anti-phytopathogenic activities%短小芽胞杆菌DX01菌株Tn5转座突变株的抑菌活性筛选体系的建立

    Institute of Scientific and Technical Information of China (English)

    胡晓璐; 陈云鹏; 沈新迁; 刘通; 顾振芳

    2012-01-01

    为建立短小芽胞杆菌Bacillus pumilus DX01菌株的Tn5转座突变株抑菌活性的高效筛选体系,采用发酵液平板抑菌法研究了各突变株发酵液对稻瘟病菌Magnaporthe grisea生长的影响,并测定了目标突变株的几丁质酶和蛋白酶活性及发酵液对稻瘟病菌分生孢子萌发的抑制率。从2 633个突变株中筛选出6个抑菌活性较对照菌株DX01显著变化的突变株。对照DX01发酵液对真菌孢子萌发的抑制率为36%,而突变株Tn5-901和Tn5-194则分别为96%和3%,抑菌活性与对照的差异达到极显著水平。其余4个突变株的几丁质酶、蛋白酶活性多重比较结果与发酵液平板抑菌结果并不完全一致,但发酵液平板抑菌法简单、高效,适用于短小芽胞杆菌突变株的抑菌活性初筛。%Inhibition of mycelial growth and conidial germination of the phytopathogenic fungus, Magna- porthe grisea by zymotic fluids of Bacillus pumilus mutants and enzymatic activities of chintinase and pro- teinase of the identified mutants were analyzed in order to establish an efficient screening system for an- tagonistic abilities in Tn5 transposon library of the B. pumilus strain DX01 and further to clone genes asso- ciated with anti-phytopathogenic activity. A total of 2 633 mutants were subjected to anti-phytopathogenic activity screening and six mutants were preliminarily identified. The tests revealed that the inhibition per- centage of M. grisea conidia that respectively treated with zymotic fluids of mutants TnS-901 and Tn5-194 and the wild-type strain DX01 were 96% , 3% , and 36%. A statistically significant difference in anti- bacterial activity between the two mutants and the control strain DX01 were found, but the other four mu- tants did not exhibit a unanimous result in the multiple comparison tests for enzymatic activities and inhi- bition of mycelial growth with bacterial zymotic fluids. In conclusion, the evaluation of inhibition of fun- gal mycelial

  18. Evaluation of the Melanocytic Pathology Assessment Tool and Hierarchy for Diagnosis (MPATH-Dx) classification scheme for diagnosis of cutaneous melanocytic neoplasms: Results from the International Melanoma Pathology Study Group.

    Science.gov (United States)

    Lott, Jason P; Elmore, Joann G; Zhao, Ge A; Knezevich, Stevan R; Frederick, Paul D; Reisch, Lisa M; Chu, Emily Y; Cook, Martin G; Duncan, Lyn M; Elenitsas, Rosalie; Gerami, Pedram; Landman, Gilles; Lowe, Lori; Messina, Jane L; Mihm, Martin C; van den Oord, Joost J; Rabkin, Michael S; Schmidt, Birgitta; Shea, Christopher R; Yun, Sook Jung; Xu, George X; Piepkorn, Michael W; Elder, David E; Barnhill, Raymond L

    2016-08-01

    Pathologists use diverse terminology when interpreting melanocytic neoplasms, potentially compromising quality of care. We sought to evaluate the Melanocytic Pathology Assessment Tool and Hierarchy for Diagnosis (MPATH-Dx) scheme, a 5-category classification system for melanocytic lesions. Participants (n = 16) of the 2013 International Melanoma Pathology Study Group Workshop provided independent case-level diagnoses and treatment suggestions for 48 melanocytic lesions. Individual diagnoses (including, when necessary, least and most severe diagnoses) were mapped to corresponding MPATH-Dx classes. Interrater agreement and correlation between MPATH-Dx categorization and treatment suggestions were evaluated. Most participants were board-certified dermatopathologists (n = 15), age 50 years or older (n = 12), male (n = 9), based in the United States (n = 11), and primary academic faculty (n = 14). Overall, participants generated 634 case-level diagnoses with treatment suggestions. Mean weighted kappa coefficients for diagnostic agreement after MPATH-Dx mapping (assuming least and most severe diagnoses, when necessary) were 0.70 (95% confidence interval 0.68-0.71) and 0.72 (95% confidence interval 0.71-0.73), respectively, whereas correlation between MPATH-Dx categorization and treatment suggestions was 0.91. This was a small sample size of experienced pathologists in a testing situation. Varying diagnostic nomenclature can be classified into a concise hierarchy using the MPATH-Dx scheme. Further research is needed to determine whether this classification system can facilitate diagnostic concordance in general pathology practice and improve patient care. Copyright © 2016 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

  19. All-fiber femtosecond laser providing 9 nJ, 50 MHz pulses at 1650 nm for three-photon microscopy

    Science.gov (United States)

    Cadroas, P.; Abdeladim, L.; Kotov, L.; Likhachev, M.; Lipatov, D.; Gaponov, D.; Hideur, A.; Tang, M.; Livet, J.; Supatto, W.; Beaurepaire, E.; Février, S.

    2017-06-01

    The spectral window lying between 1.6 and 1.7 μm is interesting for in-depth multiphoton microscopy of intact tissues due to reduced scattering and absorption in this wavelength range. However, wide adoption of this excitation range will rely on the availability of robust and cost-effective high peak power pulsed lasers operating at these wavelengths. In this communication, we report on a monolithically integrated high repetition rate (50 MHz) all-fiber femtosecond laser based on a soliton self-frequency shift providing 9 nJ, 75 fs pulses at 1650 nm. We illustrate its potential for biological microscopy by recording three-photon-excited fluorescence and third-harmonic generation images of mouse nervous tissue and developing Drosophila embryos labeled with a red fluorescent protein.

  20. Comparison of the Hologic Aptima HIV-1 Quant Dx Assay to the Roche COBAS Ampliprep/COBAS TaqMan HIV-1 Test v2.0 for the quantification of HIV-1 RNA in plasma samples

    DEFF Research Database (Denmark)

    Schønning, Kristian; Johansen, Kim; Landt, Bodil

    2017-01-01

    of the Aptima HIV-1 Quant Dx Assay (Aptima) and the COBAS Ampliprep/COBAS TaqMan HIV-1 Test v2.0 (CAPCTMv2) for the quantification of HIV-1 RNA in plasma samples. STUDY DESIGN: The performance of the two tests was compared on 216 clinical plasma samples, on dilutions series in seven replicates of five clinical...

  1. Project h[schwa]li?dx[superscript w]/Healthy Hearts across Generations: Development and Evaluation Design of a Tribally Based Cardiovascular Disease Prevention Intervention for American Indian Families

    Science.gov (United States)

    Walters, Karina L.; LaMarr, June; Levy, Rona L.; Pearson, Cynthia; Maresca, Teresa; Mohammed, Selina A.; Simoni, Jane M.; Evans-Campbell, Teresa; Fredriksen-Goldsen, Karen; Fryberg, Sheryl; Jobe, Jared B.

    2012-01-01

    American Indian and Alaska Native (AIAN) populations are disproportionately at risk for cardiovascular disease (CVD), diabetes, and obesity, compared with the general US population. This article describes the h[schwa]li?dx[superscript w]/Healthy Hearts Across Generations project, an AIAN-run, tribally based randomized controlled trial (January…

  2. ANTIPSYCHOTICS REVERSE P-GLYCOPROTEIN-MEDIATED DOXORUBICIN RESISTANCE IN HUMAN UTERINE SARCOMA MES-SA/Dx5 CELLS: A NOVEL APPROACH TO CANCER CHEMOTHERAPY.

    Science.gov (United States)

    Angelini, A; Ciofani, G; Conti, P

    2015-01-01

    Multidrug resistance (MDR) mediated by P-glycoprotein (Pgp) remains one of the major obstacles to effective cancer chemotherapy. Several chemosensitizers have been used in vivo and in vitro to reverse MDR but have exhibited several unwanted side effects. Antipsychotics are often administered to treat psychiatric disorders such as delirium, anxiety and sleep disorders in cancer patients during chemotherapy. The present in vitro study, examined the effects of two common antipsychotic compounds, haloperidol and risperidone, and a natural compound such as theobromine on reversing MDR Pgp-mediated, to evaluate their potential use as chemosensitizing agents. The human doxorubicin (doxo) resistant uterine sarcoma cells (MES-SA/Dx5) that overexpress Pgp (100-fold), were treated with the antipsychotic alone (1, 10 and 20 μM) or in combination with different concentrations of doxo (2, 4 and 8 μM). The accumulation and cytotoxicity of doxo (MTT assay) and cellular GSH content (GSH assay) in comparison with verapamil, a well-known Pgp inhibitor, used as reference molecule were examined. It was found that the three compounds significantly enhanced the intracellular accumulation of doxo in resistant cancer cells, when compared with cells receiving doxo alone (p 30%) in resistant cells, when compared to untreated control cells (peffective Pgp inhibitor with the lowest toxicity.

  3. Large-moment antiferromagnetic order in overdoped high-Tc superconductor 154SmFeAsO1-xDx

    Science.gov (United States)

    Iimura, Soshi; Okanishi, Hiroshi; Matsuishi, Satoru; Hiraka, Haruhiro; Honda, Takashi; Ikeda, Kazutaka; Hansen, Thomas C.; Otomo, Toshiya; Hosono, Hideo

    2017-05-01

    In iron-based superconductors, high critical temperature (Tc) superconductivity over 50 K has only been accomplished in electron-doped hREFeAsO (hRE is heavy rare earth (RE) element). Although hREFeAsO has the highest bulk Tc (58 K), progress in understanding its physical properties has been relatively slow due to difficulties in achieving high-concentration electron doping and carrying out neutron experiments. Here, we present a systematic neutron powder diffraction study of 154SmFeAsO1-xDx, and the discovery of a long-range antiferromagnetic ordering with x ≥ 0.56 (AFM2) accompanying a structural transition from tetragonal to orthorhombic. Surprisingly, the Fe magnetic moment in AFM2 reaches a magnitude of 2.73 μB/Fe, which is the largest in all nondoped iron pnictides and chalcogenides. Theoretical calculations suggest that the AFM2 phase originates in kinetic frustration of the Fe-3dxy orbital, in which the nearest-neighbor hopping parameter becomes zero. The unique phase diagram, i.e., highest-Tc superconducting phase adjacent to the strongly correlated phase in electron-overdoped regime, yields important clues to the unconventional origins of superconductivity.

  4. Research of the Processing Simulation Environment with Mitsubishi Gantry Machine Tools (MVR33-39DX) based on VERICUT%基于VERICUT的三菱龙门机床(MVR33-39DX)加工仿真环境研究

    Institute of Scientific and Technical Information of China (English)

    王泰吉; 李世涛; 宋福田; 徐鹏

    2016-01-01

    在应用VERICUT软件构建虚拟环境仿真数控程序时,有时会遇到机床厂商为了机床的一些特殊功能而设定的一些特殊指令,这些指令通常需要在VERICUT软件中单独做出定义.介绍了MVR33-39DX数控龙门铣床中一些特殊指令在VERICUT软件中的配置方式.%When building a virtual CNC machine simulation environment in VERICUT ,sometimes some machines have a few special commands for special features .These commands need to be configured in the VERICUT control system .De-scribe how to define special commands in the VERICUT control system for the MVR33-39DX CNC milling machine .

  5. Nanostructures of Mg0.65Ti0.35Dx studied with x-ray diffraction, neutron diffraction, and magic-angle-spinning H2 NMR spectroscopy

    Science.gov (United States)

    Srinivasan, S.; Magusin, P. C. M. M.; Kalisvaart, W. P.; Notten, P. H. L.; Cuevas, F.; Latroche, M.; van Santen, R. A.

    2010-02-01

    Magnesium transition-metal alloys have a high hydrogen-storage capacity and show improved hydrogen-uptake and -release kinetics compared to magnesium alone. In the present study we have investigated the structure of bulk magnesium-titanium deuteride Mg0.65Ti0.35Dx prepared via mechanical alloying and gas-phase deuterium absorption by combined use of x-ray diffraction (XRD), neutron diffraction, and magic-angle-spinning H2 nuclear magnetic resonance (NMR). The initial ball-milled alloy has two XRD-distinct Mg and Ti fcc phases. Even after prolonged exposure to deuterium gas at 75 bar and 175°C the materials with and without palladium catalyst are only partly deuterated. Deuterium loading causes the formation of, on the one hand, bct (rutile) MgD2 nanodomains with interdispersed TiDy layers and, on the other hand, a separate fcc (fluorite) TiDz phase. The TiDy phase is XRD invisible, but shows clearly up at a H2 NMR shift of -43ppm between the shift of MgD2 (3 ppm) and the Knight shift of the TiDz phase (-143ppm) . Exchange NMR indicates complete deuterium exchange at 25°C between the MgD2 and TiDy phase within 1 s, as consistent with intimate contacts between these phases. Combined analysis of the XRD and NMR peak areas suggests that the deuterium concentrations y and z in the TiDy and TiDz domains are about 1.5 and 2.0, respectively. Comparing the intrinsic cell parameters of rutile MgH2 and fluorite TiH2 , we propose that stabilization of the mixed nanocomposite may arise from a coherent coupling between the crystal structures of the rutile MgD2 nanodomains and the thin layers of fcc TiDy .

  6. Comparative distribution of binding of the muscarinic receptor ligands pirenzepine, AF-DX 384, (R,R)-I-QNB and (R,S)-I-QNB to human brain.

    Science.gov (United States)

    Piggott, Margaret; Owens, Jonathan; O'Brien, John; Paling, Sean; Wyper, David; Fenwick, John; Johnson, Mary; Perry, Robert; Perry, Elaine

    2002-09-01

    Quinuclidinyl benzilate (QNB) and its derivatives are being developed to investigate muscarinic receptor changes in vivo in Alzheimer's disease and dementia with Lewy bodies. This is the first study of [125I]-(R,R)-I-QNB and [125I]-(R,S)-I-QNB binding in vitro in human brain. We have compared the in vitro binding of the muscarinic ligands [3H]pirenzepine and [3H]AF-DX 384, which have selectivity for the M1 and M2/M4 receptor subtypes, respectively, to the binding of [125I]-(R,R)-I-QNB and [125I]-(R,S)-I-QNB. This will provide a guide to the interpretation of in vivo SPET images generated with [123I]-(R,R)-I-QNB and [123I]-(R,S)-I-QNB. Binding was investigated in striatum, globus pallidus, thalamus and cerebellum, and cingulate, insula, temporal and occipital cortical areas, which show different proportions of muscarinic receptor subtypes, in post-mortem brain from normal individuals. M1 receptors are of high density in cortex and striatum and are relatively low in the thalamus and cerebellum, while M4 receptors are mainly expressed in the striatum, and M2 receptors are most evident in the cerebellum and thalamus. [125I]-(R,R)-I-QNB and [125I]-(R,S)-I-QNB density distribution patterns were consistent with binding to both M1 and M4 receptors, with [125I]-(R,R)-I-QNB additionally binding to a non-cholinergic site not displaceable by atropine. This distribution can be exploited by in vivo imaging, developing ligands for both SPET and PET, to reveal muscarinic receptor changes in Alzheimer's disease and dementia with Lewy bodies during the disease process and following cholinergic therapy.

  7. Effect of acute swim stress on plasma corticosterone and brain monoamine levels in bidirectionally selected DxH recombinant inbred mouse strains differing in fear recall and extinction.

    Science.gov (United States)

    Browne, Caroline A; Hanke, Joachim; Rose, Claudia; Walsh, Irene; Foley, Tara; Clarke, Gerard; Schwegler, Herbert; Cryan, John F; Yilmazer-Hanke, Deniz

    2014-12-01

    Stress-induced changes in plasma corticosterone and central monoamine levels were examined in mouse strains that differ in fear-related behaviors. Two DxH recombinant inbred mouse strains with a DBA/2J background, which were originally bred for a high (H-FSS) and low fear-sensitized acoustic startle reflex (L-FSS), were used. Levels of noradrenaline, dopamine, and serotonin and their metabolites 3,4-dihydroxyphenyacetic acid (DOPAC), homovanillic acid (HVA), and 5-hydroxyindoleacetic acid (5-HIAA) were studied in the amygdala, hippocampus, medial prefrontal cortex, striatum, hypothalamus and brainstem. H-FSS mice exhibited increased fear levels and a deficit in fear extinction (within-session) in the auditory fear-conditioning test, and depressive-like behavior in the acute forced swim stress test. They had higher tissue noradrenaline and serotonin levels and lower dopamine and serotonin turnover under basal conditions, although they were largely insensitive to stress-induced changes in neurotransmitter metabolism. In contrast, acute swim stress increased monoamine levels but decreased turnover in the less fearful L-FSS mice. L-FSS mice also showed a trend toward higher basal and stress-induced corticosterone levels and an increase in noradrenaline and serotonin in the hypothalamus and brainstem 30 min after stress compared to H-FSS mice. Moreover, the dopaminergic system was activated differentially in the medial prefrontal cortex and striatum of the two strains by acute stress. Thus, H-FSS mice showed increased basal noradrenaline tissue levels compatible with a fear phenotype or chronic stressed condition. Low corticosterone levels and the poor monoamine response to stress in H-FSS mice may point to mechanisms similar to those found in principal fear disorders or post-traumatic stress disorder.

  8. Multi-field-of-view strategy for image-based outcome prediction of multi-parametric estrogen receptor-positive breast cancer histopathology: Comparison to Oncotype DX

    Directory of Open Access Journals (Sweden)

    Ajay Basavanhally

    2011-01-01

    Full Text Available In this paper, we attempt to quantify the prognostic information embedded in multi-parametric histologic biopsy images to predict disease aggressiveness in estrogen receptor-positive (ER+ breast cancers (BCa. The novel methodological contribution is in the use of a multi-field-of-view (multi-FOV framework for integrating image-based information from differently stained histopathology slides. The multi-FOV approach involves a fixed image resolution while simultaneously integrating image descriptors from many FOVs corresponding to different sizes. For each study, the corresponding risk score (high scores reflecting aggressive disease and vice versa, predicted by a molecular assay (Oncotype DX, is available and serves as the surrogate ground truth for long-term patient outcome. Using the risk scores, a trained classifier is used to identify disease aggressiveness for each FOV size. The predictions for each FOV are then combined to yield the final prediction of disease aggressiveness (good, intermediate, or poor outcome. Independent multi-FOV classifiers are constructed for (1 50 image features describing the spatial arrangement of cancer nuclei (via Voronoi diagram, Delaunay triangulation, and minimum spanning tree graphs in H and E stained histopathology and (2 one image feature describing the vascular density in CD34 IHC stained histopathology. In a cohort of 29 patients, the multi-FOV classifiers obtained by combining information from the H and E and CD34 IHC stained channels were able to distinguish low- and high-risk patients with an accuracy of 0.91 ± 0.02 and a positive predictive value of 0.94 ± 0.10, suggesting that a purely image-based assay could potentially replace more expensive molecular assays for making disease prognostic predictions.

  9. Multi-field-of-view strategy for image-based outcome prediction of multi-parametric estrogen receptor-positive breast cancer histopathology: Comparison to Oncotype DX.

    Science.gov (United States)

    Basavanhally, Ajay; Feldman, Michael; Shih, Natalie; Mies, Carolyn; Tomaszewski, John; Ganesan, Shridar; Madabhushi, Anant

    2011-01-01

    In this paper, we attempt to quantify the prognostic information embedded in multi-parametric histologic biopsy images to predict disease aggressiveness in estrogen receptor-positive (ER+) breast cancers (BCa). The novel methodological contribution is in the use of a multi-field-of-view (multi-FOV) framework for integrating image-based information from differently stained histopathology slides. The multi-FOV approach involves a fixed image resolution while simultaneously integrating image descriptors from many FOVs corresponding to different sizes. For each study, the corresponding risk score (high scores reflecting aggressive disease and vice versa), predicted by a molecular assay (Oncotype DX), is available and serves as the surrogate ground truth for long-term patient outcome. Using the risk scores, a trained classifier is used to identify disease aggressiveness for each FOV size. The predictions for each FOV are then combined to yield the final prediction of disease aggressiveness (good, intermediate, or poor outcome). Independent multi-FOV classifiers are constructed for (1) 50 image features describing the spatial arrangement of cancer nuclei (via Voronoi diagram, Delaunay triangulation, and minimum spanning tree graphs) in H and E stained histopathology and (2) one image feature describing the vascular density in CD34 IHC stained histopathology. In a cohort of 29 patients, the multi-FOV classifiers obtained by combining information from the H and E and CD34 IHC stained channels were able to distinguish low- and high-risk patients with an accuracy of 0.91 ± 0.02 and a positive predictive value of 0.94 ± 0.10, suggesting that a purely image-based assay could potentially replace more expensive molecular assays for making disease prognostic predictions.

  10. Neuromuscular adaptations to strength and concurrent training in elderly men. DOI: http://dx.doi.org/10.5007/1980-0037.2012v14n4p483

    Directory of Open Access Journals (Sweden)

    Luiz Fernando Martins Kruel

    2012-07-01

    Full Text Available DOI: http://dx.doi.org/10.5007/1980-0037.2012v14n4p483This paper aimed to review the results of studies on neuromuscular adaptations to strength training (ST and concurrent training (CT in elderly men. A literature search was conducted using PubMed, Scopus, and SciELO. The search was limited to studies published from 1980 to 2012. A total of 3,390 articles were retrieved. After reading their titles, 127 studies were further evaluated by reading their abstracts. This resulted in 92 papers that were read in full; 25 of these were selected and their results were described in the present review. Several studies showed that, in elderly subjects, ST can produce increases in muscle strength, power, activation and mass. ST-induced strength gain may be explained by neural and morphological adaptations. The main neural adaptations to ST included increased recruitment of motor units and increased motor unit firing rate. Morphological adaptations included increases in the physiological cross-sectional area (CSA of the muscle, in muscle thickness, in muscle fiber pennation angle, and changes in muscle myosin heavy-chain isoforms, resulting in the conversion of muscle fiber from subtype IIx to IIa. The inclusion of moderate-to-high inten- sity (60-85% of maximum strength ST in the routine of this population is recommended to improve neuromuscular function. CT can promote significant neuromuscular adaptations, but these gains may be of a lower magnitude than those obtained with ST. Although CT has an interference effect on neuromuscular adaptations, it also promotes improvement in cardiovascular function and is therefore the most frequently recommended intervention for health promotion in the elderly.

  11. Very slow decay of a defect related emission band at 2.4 eV in AlN: Signatures of the Si related shallow DX state

    Energy Technology Data Exchange (ETDEWEB)

    Lamprecht, M., E-mail: matthias.lamprecht@uni-ulm.de; Grund, C.; Neuschl, B.; Thonke, K. [Institute of Quantum Matter/Semiconductor Physics Group, University of Ulm, Albert-Einstein-Allee 45, 89069 Ulm (Germany); Bryan, Z.; Collazo, R.; Sitar, Z. [Department of Materials Science and Engineering, North Carolina State University, Raleigh, North Carolina 27606 (United States)

    2016-04-21

    We report on a defect related luminescence band at 2.4 eV in aluminum nitride bulk crystals, for which we find strong indications to be related to silicon DX centers. Time resolved photoluminescence spectroscopy using a sub-bandgap excitation reveals two different recombination processes with very long decay times of 13 ms and 153 ms at low temperature. Based on the results of temperature and excitation dependent photoluminescence experiments, the process with the shorter lifetime is assigned to a donor-acceptor pair transition involving the shallow silicon donor state, which can be emptied with a thermal dissociation energy of 65 meV. The slower process with a thermal quenching energy of 15 meV is assigned to the slightly deeper Si DX state known from electron paramagnetic resonance experiments, which is transferred back to the shallow donor state.

  12. A DDC-based capacity controller of a direct expansion (DX) air conditioning (A/C) unit for simultaneous indoor air temperature and humidity control - Pt. 1: Control algorithms and preliminary controllability tests

    Energy Technology Data Exchange (ETDEWEB)

    Li, Zheng [Institute of Air Conditioning, China Academy of Building Research, Beijing 100013 (China); Deng, Shiming [Department of Building Services Engineering, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR (China)

    2007-01-15

    For residential buildings located in the subtropics, direct expansion (DX) air conditioning (A/C) units are commonly used. Most DX A/C units are currently equipped with single-speed compressors and supply fans, relying on on-off cycling compressors as a low-cost approach to maintain only indoor air dry-bulb temperature, resulting in either space overcooling or an uncontrolled equilibrium indoor relative humidity (RH) level. With the rapid development of A/C industry, the use of variable-speed compressor and supply fan has become more and more prevalent and practical. This paper, the first part of a two-part series, reports on the development of a novel direct digital control (DDC)-based capacity controller for a DX A/C unit having variable-speed compressor and supply fan to simultaneously control indoor air temperature and RH in a conditioned space served by the DX A/C unit. The controller is the first of its kind as a composite parameter, sensible heat ratio (SHR), is used as a controlled parameter. The core element of the capacity controller, a numerical calculation algorithm (NCA) is firstly presented. This is followed by reporting the results of preliminary controllability tests of the DDC-based capacity controller, which suggested that the controller developed could achieve a reasonable control accuracy, but with room for improvement with respect to control sensitivity. Part II of the two-part series reports on the further development of the controller to improve its control sensitivity, and the results of associated controllability tests. (author)

  13. A Direct Comparison of Metabolic Responses to High-Fat Diet in C57BL/6J and C57BL/6NJ Mice.

    Science.gov (United States)

    Fisher-Wellman, Kelsey H; Ryan, Terence E; Smith, Cody D; Gilliam, Laura A A; Lin, Chien-Te; Reese, Lauren R; Torres, Maria J; Neufer, P Darrell

    2016-11-01

    Although nicotinamide nucleotide transhydrogenase (NNT)-deficient C57BL/6J (6J) mice are known to be highly susceptible to diet-induced metabolic disease, this notion stems primarily from comparisons of 6J mice to other inbred strains. To date, very few studies have directly compared metabolic disease susceptibility between NNT-deficient 6J mice and NNT-competent C57BL/6 substrains. In this study, comprehensive profiling of the metabolic response to a high-fat/high-sucrose diet (HFD) were compared across time in 6J and C57BL/6NJ (6N) mice. Given that increased peroxide exposure drives insulin resistance, coupled with the fact that NNT regulates peroxide detoxification, it was hypothesized that 6J mice would experience greater derangements in redox homeostasis/metabolic disease upon HFD exposure. Contrary to this, both lines were found to be highly susceptible to diet-induced metabolic disease, as evidenced by impairments in glucose tolerance as early as 24 h into the HFD. Moreover, various markers of the metabolic syndrome, as well as peroxide stress, were actually blunted, rather than exacerbated, in the 6J mice, likely reflecting compensatory increases in alterative redox-buffering pathways. Together, these data provide evidence that the susceptibility to HFD-induced metabolic disease is similar in the 6J and 6N substrains. Given the numerous genetic variances in the 6J stain, including loss of NNT function, these findings suggest that the 6N substrain is the more logical and representative genetic background model for metabolic studies. © 2016 by the American Diabetes Association.

  14. atlantic_city_nj.grd

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NGDC builds and distributes high-resolution, coastal digital elevation models (DEMs) that integrate ocean bathymetry and land topography to support NOAA's mission to...

  15. 智慧校园背景下的高校治安防控体系建设研究--以 NJ 高校为例%Study on the Construction of Public Security Prevention and Control System in Higher Colleges under the Background of Wisdom Campus -Take NJ Higher College as the Example

    Institute of Scientific and Technical Information of China (English)

    谢秉宸

    2016-01-01

    本文从高校治安防控工作存在的问题入手,分析 NJ 高校当前治安管理工作存在的难点及其原因,基于智慧校园背景,从构建校园应急指挥系统、引入智能停车场管理系统和袖珍公共交通系统以及建立健全群防群治网络等四个方面,提出建立高校治安防控体系建设的构想。%From the crime prevention and control work in higher colleges,there exists difficulties and reason in the work of NY of the current security management.Based on the background of the wisdom of the campus,we can put forward conception of the establishment of the crime prevention and control system from four aspects of the construction of campus emergency com-mand system,the introduction to the intelligent parking management system,the pocket public transport system as well as es-tablishing and improving the prevention and treatment network.

  16. Principle and Repair of RF PA Module for DX-Series Digital AM Transmitter%DX系列数字调幅发射机射频功放模块的原理及维修

    Institute of Scientific and Technical Information of China (English)

    赵伍民

    2004-01-01

    目前数字化全固态调幅中波发射机在逐渐取代电子管发射机.我台于1997年6月引进两台美国哈里斯DX-50型全固态数字中波发射机,在使用过程中,总结出了一些维修经验,本文对故障率较高的射频功放模块的原理进行详细介绍,并给出了维修实例.

  17. Cellular stress induced by photodynamic reaction with CoTPPS and MnTMPyPCl5 in combination with electroporation in human colon adenocarcinoma cell lines (LoVo and LoVoDX).

    Science.gov (United States)

    Kulbacka, J; Kotulska, M; Rembiałkowska, N; Choromańska, A; Kamińska, I; Garbiec, A; Rossowska, J; Daczewska, M; Jachimska, B; Saczko, J

    2013-11-01

    Two porphyrins, CoTPPS and MnTMPyPCl5, were tested for their photodynamic activity and potential novel use in a therapy of human cancers. We investigated an effect of photodynamic reaction (PDR), electroporation (EP) and their combination (electro-photodynamic reaction [EP-PDR]) on human colon adenocarcinoma cell lines (LoVo and resistant to doxorubicin LoVoDX), human breast adenocarcinoma (wild type MCF-7/WT and resistant to doxorubicin MCF-7/DOX), and human melanoma (Me45). The efficiency of macromolecules transport was examined with cytofluorymetry by assessing the degree of propidium iodide (PI) penetration. Additionally, cellular ultrastructure after EP was evaluated. We determined cyto- and photo-cytotoxic effect on the cells viability (MTT assay) after standard PDR and PDR combined with EP. Intracellular distribution and mitochondrial colocalization of both porphyrins was also performed. The experiments proved that both complexes exhibit desirable photodynamic properties on LoVo LoVoDX cells, and EP effectively supports photodynamic method in this type of cancer. The application of EP provided shorter time of incubation (only 10 min) and enhanced effect of applied therapy. The porphyrins did not affect the MCF-7 and Me45 cell lines.

  18. Spatial/temporal variations of elemental carbon, organic carbon, and trace elements in PM10 and the impact of land-use patterns on community air pollution in Paterson, NJ.

    Science.gov (United States)

    Yu, Chang Ho; Fan, Zhi-Hua; Meng, Qingyu; Zhu, Xianlei; Korn, Leo; Bonanno, Linda J

    2011-06-01

    An urban community PM10 (particulate matter pollution study was conducted in Paterson, NJ, a mixed land-use community that is interspersed with industrial, commercial, mobile, and residential land-use types. This paper examines (1) the spatial/temporal variation of PM10, elemental carbon (EC), organic carbon (OC), and nine elements; and (2) the impact of land-use type on those variations. Air samples were collected from three community-oriented locations in Paterson that attempted to capture industrial, commercial, and mobile source-dominated emissions. Sampling was conducted for 24 hr every 6 days from November 2005 through December 2006. Samples were concurrently collected at the New Jersey Department of Environmental Protection-designated air toxics background site in Chester, NJ. PM10 mass, EC, OC, and nine elements (Ca, Cu, Fe, Pb, Mn, Ni, S, Ti, and Zn) that had more than 50% of samples above detection and known sources or are toxic were selected for spatial/temporal analysis in this study. The concentrations of PM10, EC, OC, and eight elements (except S) were significantly higher in Paterson than in Chester (P 0.05). These results indicated that anthropogenic sources of air pollution were present in Paterson. The source apportionment confirmed the impact of vehicular and industrial emissions on the PM10 ambient air pollution in Paterson. The multiple linear regression analysis showed that categorical land-use type was a significant predictor for all air pollution levels, explaining up to 42% of the variability in concentration by land-use type only.

  19. YHFT-DX处理器全定制EDA技术的开发与应用%The development and application of full custom EDA techniques in YHFT-DX

    Institute of Scientific and Technical Information of China (English)

    李振涛; 刘尧; 陈书明; 徐庆光; 付志刚

    2013-01-01

    在YHFT-DX处理器的研制中,研究并实现了多项支撑全定制设计的EDA技术.针对全定制设计的功能验证,研究并实现了层次式功能模型自动提取技术,能够将晶体管级网表转化为等效的RTL级网表.研究并实现了晶体管级混合时序分析方法,可自动分析全定制设计的延时,并采用多线程并行的方法获得了约10倍左右的速度提升.为提高模拟结果分析的效率,开发了一个延时提取的工具Aimeasure.开发了两个信号完整性分析工具PNVisual和NoiseSpy,分别用于全定制设计的IR-Drop分析和噪声分析.上述技术已在YHFT-DX处理器的设计中得到了广泛应用,有效提高了全定制设计的效率与质量.%Several full custom EDA techniques were developed during the design of YHFT-DX processor. Hierarchical functional model extraction, which can convert a transistor-level netlist into an equivalent RTL netlist, were developed for the functional verification of full custom circuits. Hybrid timing analysis was researched for the transistor-level timing analysis. l0x run-time improvements were achieved by the multi-thread parallel optimization. A measurement was developed to get delays from the simulation waveforms, which improves the efficiency of simulation results analysis. Two signal integrity verification tools, PNVisual and NoiseSpy, were developed for IR-Drop and noise analysis of full custom circuits. These techniques have been widely used in the design of YHFT-DX, which greatly improves the efficiency and quality of full custom design.

  20. Physical growth and nutritional status of schoolchildren from Valley of the Jequitinhonha, Minas Gerais, Brazil. DOI: http://dx.doi.org/10.5007/1980-0037.2012v14n4p363

    Directory of Open Access Journals (Sweden)

    Dartagnan Pinto Guedes

    2012-07-01

    Full Text Available DOI: http://dx.doi.org/10.5007/1980-0037.2012v14n4p363The study analyzed physical growth and nutritional status in a representative sample of schoolchildren from the Jequitinhonha Valley region, Minas Gerais, Brazil. A total of 5100 subjects (2730 girls and 2370 boys aged 6 to 18 years were included in the study. Nutritional status of the under-10 group was assessed by z +2 for weight-for-height (overweight. For children over 10, the 5th and 85th percentiles of weight for age were used to assess underweight and overweight respectively, according to World Health Organization recommendations. Prevalence rates of overweight and obesity according to the International Obesity Task Force criteria were also calculated. The data showed a prevalence of undernutrition below the expected level for the reference population (girls, 1.2%; boys, 3.9%. The prevalence of overweight was approximately 13% for girls and 6% for boys, and obesity was 2% for both sexes. In short, the results indicated a low prevalence of undernutrition and a high prevalence of overnutrition. This shows an urgent need for implementation of educational intervention programs geared to the improvement of physical activity and appropriate dietary habits in this population.

  1. Relationship between running kinematic changes and time limit at vVO2max. DOI: http://dx.doi.org/10.5007/1980-0037.2012v14n4p428

    Directory of Open Access Journals (Sweden)

    Sebastião Iberes Lopes Melo

    2012-07-01

    Full Text Available DOI: http://dx.doi.org/10.5007/1980-0037.2012v14n4p428Exhaustive running at maximal oxygen uptake velocity (vVO2max can alter running kinematic parameters and increase energy cost along the time. The aims of the present study were to compare characteristics of ankle and knee kinematics during running at vVO2max and to verify the relationship between changes in kinematic variables and time limit (Tlim. Eleven male volunteers, recreational players of team sports, performed an incremental running test until volitional exhaustion to determine vVO2max and a constant velocity test at vVO2max. Subjects were filmed continuously from the left sagittal plane at 210 Hz for further kinematic analysis. The maximal plantar flexion during swing (p<0.01 was the only variable that increased significantly from beginning to end of the run. Increase in ankle angle at contact was the only variable related to Tlim (r=0.64; p=0.035 and explained 34% of the performance in the test. These findings suggest that the individuals under study maintained a stable running style at vVO2max and that increase in plantar flexion explained the performance in this test when it was applied in non-runners.

  2. The SocioLog.dx Experience

    DEFF Research Database (Denmark)

    Gjerdrum Pedersen, Esben Rahbek; Reitan Andersen, Kirsti

    study is part of MISTRA Future Fashion, an international research program intended to promote systemic changes toward sustainability in the fashion industry. The experts participating in the study portrayed conventional fashion as being in a state of crisis, in terms of sustainability, but also...... after a few washes. • “Fast fashion” is repeatedly criticized for creating a level of consumption that is neither socially nor environmentally sustainable. There is a need to challenge the dominant “fast fashion” business model, which is based on large quantities of new, low-priced collections...

  3. CERN_DxCTA counting mode chip

    CERN Document Server

    Moraes, D; Nygård, E

    2008-01-01

    This ASIC is a counting mode front-end electronic optimized for the readout of CdZnTe/CdTe and silicon sensors, for possible use in applications where the flux of ionizing radiation is high. The chip is implemented in 0.25 μm CMOS technology. The circuit comprises 128 channels equipped with a transimpedance amplifier followed by a gain shaper stage with 21 ns peaking time, two discriminators and two 18-bit counters. The channel architecture is optimized for the detector characteristics in order to achieve the best energy resolution at counting rates of up to 5 M counts/second. The amplifier shows a linear sensitivity of 118 mV/fC and an equivalent noise charge of about 711 e−, for a detector capacitance of 5 pF. Complete evaluation of the circuit is presented using electronic pulses and pixel detectors.

  4. Chemical and histological comparisons between Brevoortia sp. (menhaden) collected in fall 2010 from Barataria Bay, LA and Delaware Bay, NJ following the DeepWater Horizon (DWH) oil spill.

    Science.gov (United States)

    Bentivegna, Carolyn S; Cooper, Keith R; Olson, Gregory; Pena, Edwin A; Millemann, Daniel R; Portier, Ralph J

    2015-12-01

    Body burdens of PAHs were compared to histological effects in menhaden (Family: Clupeidae, Genus: Brevoortia) collected in fall 2010 from Barataria Bay, LA (BBLA) and Delaware Bay, NJ (DBNJ). Barataria Bay was heavily oiled during the DeepWater Horizon (DWH) oil spill, while Delaware Bay although urbanized had no reported recent oil spills. GCMS analyses of pre-spill 2009, BBLA and DBNJ fish found predominantly C2/C3 phenanthrene (1.28-6.52 ng/mg). However, BBLA also contained five higher molecular weight PAHs (0.06-0.34 ng/mg DW). Fluorescent aromatic compound spectroscopy (FACS) of gastrointestinal (GI) tract tissue showed statistically higher levels of hydroxypyrene-like PAHs in DBNJ than BBLA fish. Histopathologic lesions were more prevalent in BBLA than DBNJ fish. The lesion prevalence (gill, trunk kidney, epidermis, stomach) in the BBLA menhaden were significantly higher and more severe than observed in the DBNJ menhaden. Reversible lesions included gill lamellar hyperplasia, adhesions, edema, and epidermal hyperplasia. The increased pigmented macrophage centers were indicative of activated macrophages responding to connective tissue damage or other antigens. The liver hepatic necrosis and renal tissue mineralization may well have undergone repair, but damage to the kidney nephrons and hepatic/biliary regions of the liver would be slower to resolve and apparently remained after elimination of PAHs. Therefore, a direct cause and effect between DWH oil spill and increased lesion prevalence in BBLA menhaden could not be established.

  5. An international, prospective, multicenter evaluation of the combination of AdvanDx Staphylococcus QuickFISH BC with mecA XpressFISH for detection of methicillin-resistant Staphylococcus aureus isolates from positive blood cultures.

    Science.gov (United States)

    Salimnia, H; Fairfax, M R; Lephart, P; Morgan, M; Gilbreath, J J; Butler-Wu, S M; Templeton, K E; Hamilton, F J; Wu, F; Buckner, R; Fuller, D; Davis, T E; Abdelhamed, A M; Jacobs, M R; Miller, A; Pfrommer, B; Carroll, K C

    2014-11-01

    Sepsis caused by Staphylococcus aureus is a major health problem worldwide. Better outcomes are achieved when rapid diagnosis and determination of methicillin susceptibility enable early optimization of antimicrobial therapy. Eight large clinical laboratories, seven from the United States and one from Scotland, evaluated the combination of the Staphylococcus QuickFISH BC and the new mecA XpressFISH assay (both AdvanDx, Woburn, MA, USA) for the detection of methicillin-resistant S. aureus in positive blood cultures. Blood cultures flagged as positive by automated blood culture instruments and demonstrating only Gram-positive cocci in clusters on Gram stain were tested by QuickFISH, a 20-min assay. If only S. aureus was detected, mecA XpressFISH testing followed. The recovered S. aureus isolates were tested by cefoxitin disk diffusion as the reference method. The QuickFISH assay results were concordant with the routine phenotypic testing methods of the testing laboratories in 1,211/1,221 (99.1%) samples and detected 488/491 S. aureus organisms (sensitivity, 99.4%; specificity, 99.6%). Approximately 60% of the samples (730) contained coagulase-negative staphylococci or nonstaphylococci as assessed by the QuickFISH assay and were not tested further. The 458 compliant samples positive exclusively for S. aureus by the QuickFISH assay were tested by the mecA XpressFISH assay, which detected 209 of 211 methicillin-resistant S. aureus organisms (sensitivity, 99.1%; specificity, 99.6%). The mecA XpressFISH assay also showed high reproducibility, with 534/540 tests performed by 6 operators over 5 days achieving reproducible results (98.9% agreement). The combination of the Staphylococcus QuickFISH BC and mecA XpressFISH assays is sensitive, specific, and reproducible for the detection of methicillin-resistant S. aureus and yields complete results in 2 h after the blood culture turns positive.

  6. Sole Source Aquifers for NY and NJ

    Data.gov (United States)

    U.S. Environmental Protection Agency — This layer is the designated sole source aquifers of New York and New Jersey. A Sole Source Aquifer, is an aquifer that supplies 50% or more of the drinking water...

  7. Hydrology submission for Middlesex County, NJ

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Hydrology data include spatial datasets and data tables necessary for documenting the hydrologic procedures for estimating flood discharges for a flood insurance...

  8. DCS Hydraulics Submission for Sussex County, NJ

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Recent developments in digital terrain and geospatial database management technology make it possible to protect this investment for existing and future projects to...

  9. EnviroAtlas - Metrics for Paterson, NJ

    Data.gov (United States)

    U.S. Environmental Protection Agency — These EnviroAtlas web services support research and online mapping activities related to EnviroAtlas (https://www.epa.gov/enviroatlas). The layers in these web...

  10. DCS Survey Submission for Gloucester County NJ

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Survey data includes spatial datasets and data tables necessary to digitally represent data collected in the survey phase of the study. (Source: FEMA Guidelines and...

  11. DCS Terrain for Middlesex County, NJ

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Terrain data, as defined in FEMA Guidelines and Specifications, Appendix N: Data Capture Standards, describes the digital topographic data that were used to create...

  12. FLOODPLAIN MAPPING SUBMITTAL, HUNTERDON CO., NJ

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping study deliverables depict and quantify the flood risks for the study area. The primary risk classifications used are the...

  13. Anatomy training for surgeons: Which way for the future?

    African Journals Online (AJOL)

    for safe medical practice. Worldwide ... has remained core practice, even in the few schools which ... of management plan (11). ... the basic science principles needed for logical .... Parmelee D.X., Destphen D. and Borges N.J. Medical. 19.

  14. 46 CFR 7.35 - Sandy Hook, NJ to Cape May, NJ.

    Science.gov (United States)

    2010-10-01

    ... North Breakwater Light to Manasquan Inlet South Breakwater Light. (c) A line drawn along the submerged Barnegat Inlet North Breakwater to Barnegat Inlet North Breakwater Light “2”; thence to Barnegat Inlet... Absecon Inlet North Jetty to Atlantic City Light. (g) A line drawn from the southernmost point of...

  15. Best Practices Case Study: Tindall Homes - Princeton, NJ, Legends at Mansfield, Columbus, NJ

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-09-01

    Case Study of Tindall Homes, who worked with Building America to design an optimal package including advanced framing, insulated precast concrete basement walls, polyurethane foam in the walls, and R-49 of batt plus blown cellulose in the attics. Some homes included a detached garden shed with photovoltaic panel-covered roofs.

  16. Immigrant with stomach pain, distension, nausea, and fever · Dx?

    Science.gov (United States)

    Tessier, Joshua; Waller, Callie

    2017-09-01

    A 34-year-old Eritrean man presented to the emergency department with complaints of diffuse abdominal pain and distention. He had emigrated to the United States 3 months earlier, following 5 years in a refugee camp in Ethiopia. Two weeks earlier, the patient sought care at his primary care clinic and was diagnosed with post-operative urinary retention and constipation following a recent hemorrhoidectomy. A Foley catheter was inserted and provided a short period of relief. Following the visit, however, his abdominal pain worsened. He also experienced increasing abdominal distention, a declining appetite, and persistent nausea. The patient said that he was unable to urinate and had not had a bowel movement in 6 days. He also described fevers, drenching night sweats, chills, and a 4-kg weight loss over 2 months.

  17. Thirteenth International Workshop on Principles of Diagnosis (DX-2002)

    Science.gov (United States)

    2002-05-01

    Jornadas de Trabajo sobre Diagnosis. Valladolid 2001. [16] Pedro J. Abad y Antonio J. Suárez. Diagnosis de Sistemas Dinámicos Basada en Aprendizaje ...Aplicación de Técnicas de Aprendizaje a la diagnosis de Sistemas Dinámicos con Etiquetado Múltiple. In proceedings of the IX CAEPIA –TTIA. 2001. [18] A

  18. 天寿年号·佛现皇帝·宕泉造窟——俄藏敦煌文献Dx.6069+DX1400+DX2148号文书再研究%The Reign Title of Tianshou, the Buddha Reincarnated Emperor and Dangquan Grotto: Rediscussion on Dunhuang Archives (Documents No.Dx.6069+DX1400+DX2148) in Russian Collection

    Institute of Scientific and Technical Information of China (English)

    梅林

    2010-01-01

    五代宋初,敦煌莫高窟、榆林窟出现了一批于阗国王及其眷属供养像,他们是曹氏归义军政权与西域绿洲王国和亲外交的历史见证.长期以来,受制于国内外于阗史研究水平,其中的国王像通例被看做同一个人--李圣天,这当然不对,因为在图像志上说不过去.本文作为系列个案研究的先行部分,运用文献与图像互证的方法,与前贤对话,尝试突破旧说的牢笼.

  19. Hurricane Sandy Washover Deposits on Southern Long Beach Island, NJ

    Science.gov (United States)

    Bishop, J. M.; Richmond, B. M.; Kane, H. H.; Lunghino, B.

    2015-12-01

    Hurricane Sandy washover deposits were investigated at Forsyth National Wildlife Refuge (FNWR) on Southern Long Beach Island, New Jersey in order to map deposit thickness and characterize the sedimentary deposits. FNWR was chosen as a field area because there has been relatively little anthropogenic shoreline modification since washover deposition from Hurricane Sandy. Sediment, elevation, and geophysical data were collected during the April 2015 field campaign, approximately two and a half years after the storm. Sediment deposit data included trenches, stratigraphic descriptions, bulk sediment samples, push cores, Russian cores, and photos. Computed tomography (CT) scanning was conducted on push cores in order to acquire high resolution imaging of density, grain size, and sedimentary structure. Profiles of washover elevation were measured using Differential GPS with Real Time Kinematic processing. Ground Penetrating Radar data was collected to image the depth of the deposit and identify sedimentary structures. These data sets are compared to pre- and post -Sandy lidar surveys in order to determine post-Sandy modification in the two and a half years following the hurricane. We compare sediment thickness and sedimentary characteristics to hurricane Sandy deposits elsewhere along the U.S. eastern seaboard and to tsunami deposits.

  20. EnviroAtlas - Paterson, NJ - Ecosystem Services by Block Group

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset presents environmental benefits of the urban forest in 107 block groups in Paterson, New Jersey. Carbon attributes, temperature reduction,...

  1. EnviroAtlas - Paterson, NJ - Park Access by Block Group

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset shows the block group population that is within and beyond an easy walking distance (500m) of a park entrance. Park entrances were included...

  2. EnviroAtlas - Paterson, NJ - Impervious Proximity Gradient

    Data.gov (United States)

    U.S. Environmental Protection Agency — In any given 1-square meter point in this EnviroAtlas dataset, the value shown gives the percentage of impervious surface within 1 square kilometer centered over the...

  3. 78 FR 64189 - Drawbridge Operation Regulation; Raccoon Creek, Bridgeport, NJ

    Science.gov (United States)

    2013-10-28

    ... SECURITY Coast Guard 33 CFR Part 117 RIN 1625-AA09 Drawbridge Operation Regulation; Raccoon Creek... proposes to modify the operating schedule that governs the U.S. Route 130 lift Bridge over Raccoon Creek at... marine traffic transits Raccoon Creek during the summer months. To better align the operating schedule to...

  4. N.J. governor vetoes mandatory testing of psychiatric patients.

    Science.gov (United States)

    1997-06-13

    New Jersey Governor Christie Whitman conditionally vetoed a bill that would have mandated HIV testing of all patients in State psychiatric hospitals. The bill would have required patients upon admission to undergo testing for HIV, hepatitis B, hepatitis C, syphilis, gonorrhea, and other sexually transmitted diseases. Except in limited circumstances, New Jersey does not mandate HIV testing. The measure passed both houses with little opposition but the governor decided to invoke her power of conditional veto. The governor recommended that the mandatory testing and disclosure portions be deleted and replaced with a provision requiring that the patient be informed of the benefits of HIV testing and be given the option of voluntary testing.

  5. 2012 USACE Topobathy Lidar: Post Sandy (NJ & NY)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These files contain classified topographic and bathymetric lidar data as unclassified valid topographic data (1) and valid topographic data classified as ground (2),...

  6. James Stewart Polshek & Partners: Glenfield Middle School, Montclair, NJ, Citation.

    Science.gov (United States)

    Progressive Architecture, 1981

    1981-01-01

    Recipient of an architectural design citation from the 28th Progressive Architecture Awards is the fifth renovation and addition to a New Jersey school that has grown in increments from eight rooms. (Author/MLF)

  7. 76 FR 65375 - Drawbridge Operation Regulation; Passaic River, Harrison, NJ

    Science.gov (United States)

    2011-10-21

    ... SECURITY Coast Guard 33 CFR Part 117 RIN 1625-AA09 Drawbridge Operation Regulation; Passaic River, Harrison....0, at Harrison, New Jersey. The owner of the bridge has requested relief from crewing the bridge at... Passaic River at Harrison, New Jersey, has a vertical clearance in the closed position of 24 feet at...

  8. 76 FR 37039 - Drawbridge Operation Regulation; Passaic River, Harrison, NJ

    Science.gov (United States)

    2011-06-24

    ... SECURITY Coast Guard 33 CFR Part 117 RIN 1625-AA09 Drawbridge Operation Regulation; Passaic River, Harrison... across the Passaic River, mile 5.0, at Harrison, New Jersey. The owner of the bridge has requested relief... Amtrak Dock Bridge, mile 5.0, across the Passaic River, at Harrison, New Jersey, has a vertical...

  9. 2013 NOAA NGS Topobathy Lidar: Great Egg (NJ)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data were collected by the National Oceanic Atmospheric Administration National Geodetic Survey Remote Sensing Division using a Riegl VQ820G system. The data...

  10. Northeast Groundfish Recreational demand survey of anglers, ME through NJ

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Stated preference choice experiment data were collected in conjunction with NMFS’ Marine Recreational Fisheries Statistics Survey (MRFSS) along the coastal states of...

  11. EnviroAtlas - Paterson, NJ - Near Road Block Group Summary

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset addresses the tree buffer along heavily traveled roads. The roads are interstates, arterials, and collectors within the EnviroAtlas...

  12. 76 FR 13288 - Drawbridge Operation Regulations; Hackensack River, Secaucus, NJ

    Science.gov (United States)

    2011-03-11

    ... of the Upper Hack Bridge at mile 6.9, across the Hackensack River, at Secaucus, New Jersey. The..., Docket Operations, telephone 202-366-9826. SUPPLEMENTARY INFORMATION: The Upper Hack Bridge, across the.... Under this temporary deviation the Upper Hack Bridge, mile 6.9, across the Hackensack River may...

  13. EnviroAtlas - Paterson, NJ - Near Road Tree Buffer

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset addresses the tree buffer along heavily traveled roads. The roads are interstates, arterials, and collectors within the EnviroAtlas...

  14. Food for Thought: Expanding School Breakfast to NJ Students. [Updated

    Science.gov (United States)

    Advocates for Children of New Jersey, 2014

    2014-01-01

    Often, school districts are reluctant to adopt innovative approaches to serving children breakfast in school because of logistical concerns that are easily overcome. Districts that adopt these more innovative approaches report significant increases in participation rates and improvement in student behavior and performance. This report provides…

  15. 75 FR 18553 - New Jersey Disaster # NJ-00014

    Science.gov (United States)

    2010-04-12

    .... Small Business Administration, Processing and Disbursement Center, 14925 Kingsport Road, Fort Worth, TX...: Burlington, Camden, Cumberland, Hudson, Hunterdon, Ocean, Salem, Sussex, Warren. Delaware: New Castle....

  16. 76 FR 56859 - New Jersey Disaster Number NJ-00023

    Science.gov (United States)

    2011-09-14

    ...: U.S. Small Business Administration, Processing and Disbursement Center, 14925 Kingsport Road, Fort...: Burlington, Ocean. Delaware: New Castle. Pennsylvania: Bucks, Delaware, Monroe, Northampton,...

  17. 76 FR 64420 - New Jersey Disaster #NJ-00022

    Science.gov (United States)

    2011-10-18

    ... Administration, Processing and Disbursement Center, 14925 Kingsport Road, Fort Worth, TX 76155. FOR FURTHER... Jersey: Atlantic, Camden, Cumberland, Salem. Delaware: New Castle. Pennsylvania: Delaware,...

  18. 76 FR 36164 - New Jersey Disaster #NJ-00021

    Science.gov (United States)

    2011-06-21

    ..., Processing and Disbursement Center, 14925 Kingsport Road, Fort Worth, TX 76155. FOR FURTHER INFORMATION..., Camden, Cumberland, Salem. Delaware: New Castle. Pennsylvania: Delaware, Philadelphia The Interest...

  19. James Stewart Polshek & Partners: Glenfield Middle School, Montclair, NJ, Citation.

    Science.gov (United States)

    Progressive Architecture, 1981

    1981-01-01

    Recipient of an architectural design citation from the 28th Progressive Architecture Awards is the fifth renovation and addition to a New Jersey school that has grown in increments from eight rooms. (Author/MLF)

  20. EnviroAtlas - Paterson, NJ - Land Cover by Block Group

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset describes the percentage of each block group that is classified as impervious, forest, and green space. Forest is just trees and forest....

  1. 2013 NOAA NGS Topobathy Lidar: Little Egg (NJ)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data were collected by the National Oceanic Atmospheric Administration National Geodetic Survey Remote Sensing Division using a Riegl VQ820G system. The data...

  2. 75 FR 28766 - Drawbridge Operation Regulations; Passaic River, Clifton, NJ

    Science.gov (United States)

    2010-05-24

    ... construction of the new Route 3 highway bridge. The best alternative and least disruptive impact to the... National Technology Transfer and Advancement Act (NTTAA) (15 U.S.C. 272 note) directs agencies to use...

  3. DIGITAL FLOOD INSURANCE RATE MAP DATABASE, HUNTERDON CO., NJ

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

  4. EnviroAtlas - Paterson, NJ - Greenspace Proximity Gradient

    Data.gov (United States)

    U.S. Environmental Protection Agency — In any given 1-square meter point in this EnviroAtlas dataset, the value shown gives the percentage of square meters of greenspace within 1/4 square kilometer...

  5. EnviroAtlas - Paterson, NJ - Demographics by Block Group

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset is a summary of key demographic groups for the EnviroAtlas community. This dataset was produced by the US EPA to support research and online...

  6. The Relative Influence of Faculty Mobility on NJ HSPA Scores

    Science.gov (United States)

    Graziano, Dana

    2013-01-01

    In this study, the researcher examined the strength and direction of relationships between New Jersey School Report Card Variables, in particular Faculty Mobility, and 2009-2010 New Jersey High School Proficiency Assessment (HSPA) Math and Language Arts Literacy test scores. Variables found to have an influence on standardized test scores in the…

  7. EnviroAtlas - Paterson, NJ - Proximity to Parks

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset shows the approximate walking distance from a park entrance at any given location within the EnviroAtlas community boundary. The zones are...

  8. 2004 FEMA Lidar: Portions of Burlington and Camden Counties (NJ)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In early October 2004, LIDAR was flown for Burlington and Camden Counties. The acquisition is being sponsored FEMA because of the July flood. It will be delivered to...

  9. Aplicación de la clasificación internacional del funcionamiento, la discapacidad y la salud, versión niños y jóvenes CIF-NJ en contextos educativos: facilitación de los procesos de inclusión de personas en situación de discapacidad intelectual en la secundaria / Application of the international classification of functioning, disability and health, version children and youth (ICF–CY), in educational contexts: facilitation the inclusive education of persons with intellectual disability in secondary school

    OpenAIRE

    Bernal Castro, Carol Andrea

    2009-01-01

    El presente estudio, buscó identificar elementos que posibilitaran la construcción de perfiles educativos funcionales, que permitieran analizar y avanzar en los procesos de inclusión educativa de algunos niños y jóvenes con discapacidad intelectual, principalmente en las etapas de ingreso, permanencia y promoción en la secundaria. Se utilizó la CIF-NJ como referente para el diseño de una herramienta de valoración que permitiera obtener dichos perfiles para su utilización en contextos educativ...

  10. Adesina and Adeniji Afr., J. Infect. Dis. (2016) 10 (1): 21 – 24 http://dx ...

    African Journals Online (AJOL)

    Proff.Adewunmi

    Materials and Methods: Three millilitres venous blood was collected from each of one ... of fresh dengue infections for the first time in Ile-Ife among different groups of people. ... Dengue, a mosquito borne viral infection caused by Dengue virus, ...

  11. DX 电休克治疗机的改进

    Institute of Scientific and Technical Information of China (English)

    胡世军; 耿文利

    2003-01-01

    @@ 电抽搐治疗(Electric Convulsive Therapy,ECT)又称电休克治疗 (Electric Shock Therapy,EST),是在安全范围内使一定量的电流通过大脑,引起意识丧失与痉挛发作以治疗精神疾患的方法.因其简单易行,副作用少,已成为精神科临床常用的治疗方法.DX型电休克治疗机由上海医疗器械专科学校生产,为了提高治疗效果,我们进行了一些改进,现介绍如下.

  12. http://dx.doi.org/10.4314/evj.v17i1.7

    African Journals Online (AJOL)

    more likelihood of the disease occurrence in calves under 3 months than ..... management system with confined indoor housing whereas lambs and kids were ..... Urquhart, G. M., Armour, J., Duncan, J. L., Dunn, A. M., Jennings, F. W., 1987.

  13. http://dx.doi.org/10.4314/evj.v17i1.4

    African Journals Online (AJOL)

    infection through different management approaches, need to address the ... concurrent infection of trypanosomosis and GI helminthes infection under field ..... Urquhart GM, Armour J, Duncan J.L., Dunn A.M., and Jennings, F.W., 1996.

  14. 82 VERNACULARISM AS IDEOLOGY Eric Omazu* http://dx.doi.org ...

    African Journals Online (AJOL)

    Ike Odimegwu

    If social relations reveals anything contrary to this reality, to the fact that all human ... grown slaves commanded higher prices than their imported counterparts ... transportation into other fields like architecture, medicine, and so on. However ...

  15. Zc(3900 ) as a resonance from the D DxAF* interaction

    Science.gov (United States)

    He, Jun

    2015-08-01

    In this paper it is proposed that the charged charmonium-like state Zc(3900 ) is a resonance above the threshold from the D D¯* interaction. The D D¯* interaction is described by the one-boson exchange model with light meson exchanges plus a short-range J /ψ exchange. The scattering amplitude is calculated within a Bethe-Salpeter equation approach, and the poles near the D D¯* threshold are searched. In the isoscalar sector, two poles found under the D D¯* threshold—i.e., bound states—have the quantum numbers IG(JPC)=0-(1+-) and 0+(1++). The latter can be related to the X (3872 ). In the isovector sector, a bound state with IG(JP)=1+(1+) is found with a large cutoff at about 3 GeV. If a cutoff at about 2 GeV is adopted with which a pole carrying the quantum number of the X (3872 ) is produced at an energy of about 3871 MeV, the pole for the bound state with 1+(1+) runs across the threshold to a second Riemann sheet and becomes a resonance above the D D¯* threshold, which can be identified with the Zc(3900 ). With such a cutoff, the D D¯* invariant mass spectrum is also investigated and the experimental results found by BESIII can be reproduced.

  16. http://dx.doi.org/10.4314/ajtcam.v9i2.1

    African Journals Online (AJOL)

    AJTCAM

    1Institute of Genetic Engineering, Southern Medical University,1838 North Guangzhou Road, ... Many clinical trials showed that CKI plus TACE can reduce the adverse reactions and improve quality of life for .... in Chinese journals. According ...

  17. Unified formulation for URANS and LES in DxUNSp code

    Directory of Open Access Journals (Sweden)

    Catalin NAE

    2009-09-01

    Full Text Available The aim of this work is to find a unified and efficient implementation of a LES turbulence model in an existing URANS CFD code, initially based on unsteady RANS equations with a k-ε turbulence model. This code has the capability to be developed for nonreacting/reacting multifluid flows in research applications. The paper intends to present mainly three aspects of this implementation for unstructured mesh based solvers, for high Reynolds compressible flows: the influence of the numerical reconstruction scheme on the results for compressible LES, the influence of the compressible SGS modeling and the efficient implementation of a wall-law based approach for complex geometry. The results will be presented for a test case (3D flow over a square cylinder at Reynolds = 22.000 [0] and compared with experimental data and other simulations. Some details for the computational efficiency and implementation on parallel computer cluster at INCAS will also be presented [0].

  18. dE/dx measurement in the ATLAS Pixel Detector and its use for particle identification

    CERN Document Server

    The ATLAS collaboration

    2011-01-01

    The ATLAS Pixel Detector provides a measurement of the charge deposited by each track crossing it. This note presents a study of how this information can be used to identify low beta particles. This study uses hits recorded in the 7 TeV proton-proton collisions during the 2010 run period and the corresponding Monte Carlo simulation. The track reconstruction has been done in the standard ATLAS software environment.

  19. http://dx.doi.org/10.4314/ajtcam.v10i4.6

    African Journals Online (AJOL)

    AJTCAM

    traditional Chinese medicinal herbs used to alleviate pain, increase circulation, and ... resistance index of the total extract of CF in MDR KB-V1 cells and its synergistic ... To overcome MDR, enormous efforts have been exerted to identify novel ...

  20. https://dx.doi.org/10.4314/jae.v21i2.6

    African Journals Online (AJOL)

    User

    Combining ability analysis for within-boll yield components in upland ... Adoption of the “Conservation farming” practice in maize production by small holder farmers in the Makoni ... and nutritional quality of tomato varieties. African Journal of ...

  1. Particle identification using dE/dx in the Mark II detector at the SLC

    Energy Technology Data Exchange (ETDEWEB)

    Boyarski, A.; Coupal, D.P.; Feldman, G.J.; Hanson, G.; Nash, J.; O' Shaughnessy, K.F.; Rankin, P.; Van Kooten, R.

    1989-04-01

    The central drift chamber in the Mark II detector at the SLAC Linear Collider has been instrumented with 100-MHz Flash-ADCs. Pulse digitization provides particle identification through the measurement of average ionization loss in the chamber. We present the results of a study of system performance and outline the systematic corrections that optimize resolution. The data used are from a short test run at PEP with one-third of the FADCs installed and an extensive cosmic ray sample with the fully instrumented chamber. 11 refs., 9 figs.

  2. The 2DX robot: a membrane protein 2D crystallization Swiss Army knife.

    Science.gov (United States)

    Iacovache, Ioan; Biasini, Marco; Kowal, Julia; Kukulski, Wanda; Chami, Mohamed; van der Goot, F Gisou; Engel, Andreas; Rémigy, Hervé-W

    2010-03-01

    Among the state-of-the-art techniques that provide experimental information at atomic scale for membrane proteins, electron crystallography, atomic force microscopy and solid state NMR make use of two-dimensional crystals. We present a cyclodextrin-driven method for detergent removal implemented in a fully automated robot. The kinetics of the reconstitution processes is precisely controlled, because the detergent complexation by cyclodextrin is of stoichiometric nature. The method requires smaller volumes and lower protein concentrations than established 2D crystallization methods, making it possible to explore more conditions with the same amount of protein. The method yielded highly ordered 2D crystals diffracting to high resolution from the pore-forming toxin Aeromonas hydrophila aerolysin (2.9A), the plant aquaporin SoPIP2;1 (3.1A) and the human aquaporin-8 (hAQP8; 3.3A). This new method outperforms traditional 2D crystallization approaches in terms of accuracy, flexibility, throughput, and allows the usage of detergents having low critical micelle concentration (CMC), which stabilize the structure of membrane proteins in solution.

  3. 4 http://dx.doi.org/10.4322/cto.2014.006

    Directory of Open Access Journals (Sweden)

    Fernando Sfair Kinker

    2014-04-01

    Full Text Available The objective of this paper is to make a reflection on the contradictions and the alleged rehabilitative potential of labor-therapeutic practices, starting from the experience developed by the Work Center of the Mental Health Program of the Municipality of Santos from 1989 to 1996, from the beginning of the intervention in the psychiatric hospital to the implementation of territorial and community services. The labor-therapeutic practice is characterized here as a disciplinary technology of deviation control, operating in line with the psychiatric paradigm. On the other hand, work projects that combine mental health and solidarity economy are considered devices that multiply opportunities, expand social networks and transform the concrete conditions of life, contributing to deconstruct the psychiatric paradigm and the sociability of merchandise. The ideas herein presented are part of a doctoral thesis that used the experience report of the Work Center implementation as a method, articulating the theoretical perspective of deinstitutionalization and the discussion of complexity, presenting new emancipatory possibilities of dealing with the issue of labor in the mental health field.

  4. Demonstration & Testing of ClimaStat for Improved DX Air-Conditioning Efficiency

    Science.gov (United States)

    2013-04-01

    ClimaStat technology installed, which likely results in longer compressor life as well as sustainability of improved efficiency: compressor temperature...Canaveral AFS Demonstration Site Patrick Air Force Base is a 21,500-acre installation located a few miles from Cocoa Beach, FL, about 50 miles east...cooler with ClimaStat technology installed as shown in Figure 6.3-5, which likely will result in longer compressor life as well as sustainability of

  5. Book Review Ngozi Ezenwa-Ohaeto* http://dx.doi.org/10.4314/og ...

    African Journals Online (AJOL)

    Dean SPGS NAU

    On what and for what reason would anybody dare pay any price again for this ... positive change in the mist of social rot. My curiosity .... the sensitive sectors such as the judiciary, universities and media .... read for senior secondary classes.

  6. Fever, rash, and leukopenia in a 32-year-old man · Dx?

    Science.gov (United States)

    Gauer, Robert; Hu, Collin; Beaman, Lindsey

    2017-10-01

    A 32-year-old man was admitted to our hospital with fever, chills, malaise, leukopenia, and a rash. About 3 weeks earlier, he'd had oral maxillofacial surgery and started a 10-day course of prophylactic amoxicillin/clavulanic acid. Fifteen days after the surgery, he developed a fever (temperature, 103° F), chills, arthralgia, myalgia, cough, diarrhea, and malaise. He was seen by his physician, who obtained a chest x-ray showing a lingular infiltrate. The physician diagnosed influenza and pneumonia in this patient, and prescribed oseltamivir, azithromycin, and an additional course of amoxicillin/clavulanic acid. Upon admission to the hospital, laboratory tests revealed a white blood cell count (WBC) of 3.1 k/mcL (normal: 3.2-10.8 k/mcL). The patient's physical examination was notable for lip edema, white mucous membrane plaques, submandibular and inguinal lymphadenopathy, and a morbilliform rash across his chest. Broad-spectrum antibiotics were initiated for presumed sepsis. On hospital day (HD) 1, tests revealed a WBC count of 1.8 k/mcL, an erythrocyte sedimentation rate of 53 mm/hr (normal: 20-30 mm/hr for women, 15-20 mm/hr for men), and a C-reactive protein level of 6.7 mg/dL (normal: <0.5 mg/dL). A repeat chest x-ray and orofacial computerized tomography scan were normal. By HD 3, all bacterial cultures were negative, but the patient was positive for human herpesvirus-6 on viral cultures. His leukopenia persisted and he had elevated levels of alanine transaminase ranging from 40 to 73 U/L (normal: 6-43 U/L) and aspartate aminotransferase ranging from 66 to 108 U/L (normal range: 10-40 U/L), both downtrending during his hospitalization. He also had elevated levels of antinuclear antibodies and anti-Smith antibody titers. A posterior-auricular biopsy was consistent with lymphocytic perivasculitis. The rash continued to progress, involving his chest, abdomen, and face. Bacterial and viral cultures remained negative and on HD 4, broad-spectrum antibiotics were discontinued.

  7. http://dx.doi.org/10.4314/ajtcam.v10i4.4

    African Journals Online (AJOL)

    AJTCAM

    a Department of Radiation Oncology, Dalian Medical University ... malignant serous cavity effusion, lung, gastrointestinal tumour, brain tumour and other superficial .... Anti-tumor effect of β-elemene in glioblastoma cells depends on p38 MAPK.

  8. http://dx.doi.org/10.4314/evj.v17i2.1

    African Journals Online (AJOL)

    Parasitism represents a major obstacle to the development of sub-sectors of livestock (Malone et ... Following the judgments passed by FAO (1994), animals fit for human consumption ..... animal reproductive system (Graber and Daynes, 1974). With regard to .... A geographical information system forecast model for strategic ...

  9. Investigation of optimal position for implantable loop recorders by potential mapping with Reveal DX

    Directory of Open Access Journals (Sweden)

    Akira Kawashima

    2015-06-01

    Conclusions: Exploring areas around the left sternal border of the fourth intercostal space – where the R wave amplitudes are least affected by body positions – is a reliable method for choosing implantation locations for ILRs.

  10. Investigation of (d,x) nuclear reactions on natural ytterbium up to 24 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Khandaker, Mayeen Uddin, E-mail: mu_khandaker@um.edu.my [Department of Physics, University of Malaya, 50603 Kuala Lumpur (Malaysia); Haba, Hiromitsu [Nishina Center for Accelerator-Based Science, RIKEN, Wako, Saitama 351-0198 (Japan); Otuka, Naohiko [Nuclear Data Section, Division of Physical and Chemical Sciences, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, A-1400 Vienna (Austria); Usman, Ahmed Rufa’i [Department of Physics, University of Malaya, 50603 Kuala Lumpur (Malaysia)

    2014-09-15

    Production cross-sections of the {sup nat}Yb(d,x){sup 169,170,171,172,173,174m,174,176m,177g}Lu and {sup 169,175,177}Yb reactions have been measured from a 24-MeV deuteron energy down to their respective thresholds by using a stacked-foil activation technique combined with high resolution γ-ray spectrometry. Our new experimental data extended the experimental database toward the lower energy region for {sup 169}Yb, {sup 171}Lu, {sup 172}Lu, and {sup 176m}Lu, and the higher region for {sup 174}Lu, {sup 176m}Lu, and {sup 177}Yb. An overall good agreement is found with some of the earlier measurements, whereas a partial agreement is obtained with the theoretical data extracted from the TENDL-2013 library. The (d,p) channel contribution underestimated by the TENDL-2013 library is successfully reproduced in the global renormalization by Ignatyuk for the FENDL-3.0 library. The production cross-sections of {sup 175}Yb available in the literature were revised based on the latest γ-ray intensity adopted in 2004. Physical thick target yields for the investigated reaction products were also deduced and compared with the directly measured ones in the literature. The derived thick target yields for {sup 173}Lu and {sup 174g}Lu are higher than the directly measured ones by Dmitriev et al. at 22 MeV. The deduced yield curves indicate that a low energy (<11 MeV) cyclotron and a highly enriched {sup 176}Yb target could be used to obtain {sup 177g}Lu with negligible impurity from {sup 177m}Lu.

  11. International Power Sources Symposium, 33rd, Cherry Hill, NJ, June 13-16, 1988, Proceedings

    Science.gov (United States)

    The present conference discusses Li rechargeable batteries, oxyhalide nonrechargeable batteries, reserve and thermal batteries, nonrechargeable thermal batteries, aqueous rechargeable and nonrechargeable batteries, advanced rechargeable batteries, high power/pulse power ambient temperature batteries, Li nonrechargeable batteries, fuel cells, and power generation/conditioning/charging technologies. Attention is given to the layer-formation of Li and its implications for secondary Li batteries, spirally wound Li-TiS2 cells, the electrochemistry of C relative to batteries and fuel cells, glass-seal corrosion in Li-SOCl2 batteries, a lithium-thionyl chloride battery for missile applications, low temperature thermal battery electrolytes, Al-air batteries, ovonic Ni/metal hydride batteries, Na/S cells, ultracapacitor filtering characteristics, long-life 'coin' cells, AgO cathode decomposition, and monolithic fuel-cell designs.

  12. School Stability: Improving Academic Achievement for NJ Foster Children. Policy Brief

    Science.gov (United States)

    Bernard-Rance, Kourtney; Parello, Nancy

    2014-01-01

    Children in New Jersey's foster care system are more likely to remain in their home school when they enter foster care, thanks to a law passed in 2010, giving these fragile children improved educational stability. The law allows children to remain in their "school of origin" when they are placed in foster care, even if the foster home is…

  13. EnviroAtlas - Paterson, NJ - Demographics by Block Group Web Service

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas web service supports research and online mapping activities related to EnviroAtlas (https://www.epa.gov/enviroatlas). This EnviroAtlas dataset is a...

  14. EnviroAtlas - Paterson, NJ - Estimated Percent Tree Cover Along Walkable Roads

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset estimates tree cover along walkable roads. The road width is estimated for each road and percent tree cover is calculated in a 8.5 meter...

  15. EnviroAtlas - Paterson, NJ - Residents with Potential Window Views of Trees by Block Group

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset shows the total block group population and the percentage of the block group population that has little access to potential window views of...

  16. TIGER/Line Shapefile, 2013, county, Ocean County, NJ, Current Address Ranges Relationship File

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The TIGER/Line shapefiles and related database files (.dbf) are an extract of selected geographic and cartographic information from the U.S. Census Bureau's Master...

  17. EnviroAtlas - Paterson, NJ - BenMAP Results by Block Group

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset demonstrates the effect of changes in pollution concentration on local populations in 107 block groups in Paterson, New Jersey. The US EPA's...

  18. 76 FR 11399 - Proposed Amendment to and Establishment of Restricted Areas, Warren Grove; NJ

    Science.gov (United States)

    2011-03-02

    ... Airspace Docket No. 11-AEA-2) and be submitted in triplicate to the Docket Management System (see ADDRESSES... the VOR Federal airway structure and therefore would have no impact on the airways in the vicinity... 48 hours in advance. Controlling agency. FAA, New York ARTCC. Using agency. New Jersey ANG, 177th...

  19. EnviroAtlas - Paterson, NJ - Estimated Intersection Density of Walkable Roads

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset estimates the intersection density of walkable roads within a 750 meter radius of any given 10 meter pixel in the community. Intersections...

  20. Power Sources Symposium, 27th, Atlantic City, N.J., June 21-24, 1976, Proceedings

    Science.gov (United States)

    1976-01-01

    A lithium-chlorine rechargeable battery is considered along with an FeS electrode development for a secondary Li5Si-FeS battery, the sodium-sulfur battery, nickel battery systems for electric vehicles, reactions in lithium thionyl chloride cells, progress in the development of lithium inorganic batteries, a stable electrolyte for Li/SO2 reserve cells, and rechargeable lithium transition metal sulfide batteries. Attention is also given to thermal runaway tests on nickel-cadmium aircraft batteries, the development of nickel-zinc batteries for aircraft, an evaluation of sealed lead acid batteries for aircraft applications, the charging of sealed lead-acid batteries, hydrogen recombination in sealed nickel-cadmium cells, the characteristics of nickel-hydrogen flight cells, the lithium-iodine cell, low power methanol fuel cells, and a nuclear battery hybrid configuration study.

  1. Power Sources Symposium, 31st, Atlantic City, NJ, June 11-14, 1984, Proceedings

    Science.gov (United States)

    1984-01-01

    The present conference on electrochemical power sources encompasses systems of such types as the thermoelectric, advanced rechargeable, lithium reserve, rechargeable, and nonrechargeable, nickel-cadmium and nickel-hydrogen rechargeable, lead-acid, nickel-zinc and nickel-iron rechargeable, nickel-cadmium and nickel-hydrogen rechargeable, and fuel cells. Attention is given to Si-Ge alloy multicouple technology, sodium-sulfur battery development status, the safety aspects of a rechargeable lithium C cell, fiber-structure electrodes for nickel-cadmium batteries, energy density improvements in Li/carbon monofluoride cells, zinc-air button cell technology, catalyzed cathodes for Li/SOCl2 cells, the effect of polymer structure on the rate capability of the lithium-iodine cell, and a methanol fuel cell powerplant.

  2. Power Sources Conference, 29th, Atlantic City, NJ, June 9-12, 1980, Proceedings

    Science.gov (United States)

    1981-01-01

    Fuel systems are considered along with thermal batteries, primary batteries, lithium primary batteries, lithium/sulfur dioxide primary batteries, lithium/oxychloride primary batteries, high temperature secondary batteries, advanced secondary batteries, and nickel secondary batteries. Attention is given to a Ni-Fe battery with gas recombination device and state-of-charge indication, the development of the nickel-iron battery system for electric vehicle propulsion, improved lead-acid batteries, the behavior of the lead-acid batteries used to start the military vehicles at low temperatures, a life cycle energy analysis of the lead-acid battery, and the anodic corrosion of fiber reinforced lead composites for use in lead-acid submarine batteries. A description is presented of the key physical characteristics for predicting Zr powder burn times, the production of zirconium metal powder for rapid rise time thermal battery application, and high rate lithium-iron disulfide batteries.

  3. New Jersey 2002 High Resolution Orthophotography (MrSID format) submission for Middlesex, NJ

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Digital color infrared (CIR) orthophotography of New Jersey in State Plane NAD83 Coordinates, U.S. Survey Feet. The digital orthophotography was produced at a scale...

  4. EnviroAtlas - Paterson, NJ - Meter-Scale Urban Land Cover (MULC) Data (2010)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Paterson, New Jersey EnviroAtlas Meter-Scale Urban Land Cover (MULC) data comprises approximately 66 km2 around the city of Paterson. The land cover data were...

  5. EnviroAtlas - Paterson, NJ - One Meter Resolution Urban Land Cover (2010) Web Service

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Paterson, New Jersey EnviroAtlas One Meter-scale Urban Land Cover Web Service comprises approximately 66 km2 around the city of Paterson. The land cover data...

  6. 78 FR 2251 - Expansion of Foreign-Trade Zone 44; Morris County, NJ

    Science.gov (United States)

    2013-01-10

    ..., notice inviting public comment has been given in the Federal Register (76 FR 80885, 12/27/11) and the...; ] DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Expansion of Foreign-Trade Zone 44; Morris County,...

  7. 78 FR 76195 - Drawbridge Operation Regulations; Passaic River, Newark and Harrison, NJ

    Science.gov (United States)

    2013-12-17

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Passaic River, Newark and Harrison..., mile 5.0, between Newark and Harrison, New Jersey. This deviation allows the AMTRACK Dock Bridge,...

  8. Superhero School Reform Heading Your Way: Now Playing in Newark, NJ

    Science.gov (United States)

    Karp, Stan

    2011-01-01

    Watching the rise to fame of Michelle Rhee, the former Washington, D.C., schools chancellor who is one of the heroes of director Davis Guggenheim's "Waiting for 'Superman'," the author was struck by how the targets had changed. Clark's baseball bat was aimed at the young black males who were demonized as a criminal element in the schoolyard.…

  9. 76 FR 53045 - Prevailing Rate Systems; Abolishment of Monmouth, NJ, as a Nonappropriated Fund Federal Wage...

    Science.gov (United States)

    2011-08-25

    ... System Wage Area AGENCY: U.S. Office of Personnel Management. ACTION: Interim rule with request for... Management, Room 7H31, 1900 E Street, NW., Washington, DC 20415-8200; email pay-leave-policy@opm.gov ; or FAX... / Thursday, August 25, 2011 / Rules and Regulations#0;#0; ] OFFICE OF PERSONNEL MANAGEMENT 5 CFR Part 532...

  10. 芜湖滚动NJ309EV车件产品通过检测

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    为做好汽车用轴承套圈配套工作,芜湖市滚动轴承制造有限公司制订了一系列相关文件,狠抓落实、加大考核,并强化工艺管理和生产现场“5S”管理,产品质量稳定并达到或超过国家相关标准,保证了客户需要。

  11. EnviroAtlas - Paterson, NJ - 51m Riparian Buffer Forest Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is forested. There is a potential for decreased water quality in areas where the...

  12. EnviroAtlas - Paterson, NJ - 15m Riparian Buffer Forest Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset describes the percentage of a 15-m riparian buffer that is forested. There is a potential for decreased water quality in areas where the...

  13. FEMA RiskMAP Atlantic, Ocean, and Monmouth, NJ Area of Interest (AOI)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Lidar data was acquired over a 1613 square mile area of interest over Atlantic, Ocean, and Monmouth Counties, New Jersey. The lidar data had a nominal point spacing...

  14. 77 FR 47334 - Safety Zone; Red Bull Flugtag, Delaware River; Camden, NJ

    Science.gov (United States)

    2012-08-08

    ... Instruction. Under Figure 2-1, paragraph 34(h), of the Instruction, an ``Environmental Analysis Check List... States, on the relationship between the national government and the States, or on the distribution of... between the Federal Government and Indian tribes, or on the distribution of power and...

  15. EnviroAtlas - Paterson, NJ - 15m Riparian Buffer Vegetated Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset describes the percentage of a 15-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the...

  16. EnviroAtlas - Paterson, NJ - 51m Riparian Buffer Vegetated Cover

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset describes the percentage of a 51-m riparian buffer that is vegetated. There is a potential for decreased water quality in areas where the...

  17. EnviroAtlas - Paterson, NJ - Riparian Buffer Land Cover by Block Group

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset describes the percentage of different land cover types within 15- and 50-meters of hydrologically connected streams, rivers, and other water...

  18. Superhero School Reform Heading Your Way: Now Playing in Newark, NJ

    Science.gov (United States)

    Karp, Stan

    2011-01-01

    Watching the rise to fame of Michelle Rhee, the former Washington, D.C., schools chancellor who is one of the heroes of director Davis Guggenheim's "Waiting for 'Superman'," the author was struck by how the targets had changed. Clark's baseball bat was aimed at the young black males who were demonized as a criminal element in the…

  19. EnviroAtlas - Paterson, NJ - Tree Cover Configuration and Connectivity, Water Background Web Service

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas web service supports research and online mapping activities related to EnviroAtlas (https://www.epa.gov/enviroatlas). The EnviroAtlas Durham, NC...

  20. Superhero School Reform Heading Your Way: Now Playing in Newark, NJ

    Science.gov (United States)

    Karp, Stan

    2011-01-01

    Watching the rise to fame of Michelle Rhee, the former Washington, D.C., schools chancellor who is one of the heroes of director Davis Guggenheim's "Waiting for 'Superman'," the author was struck by how the targets had changed. Clark's baseball bat was aimed at the young black males who were demonized as a criminal element in the…

  1. 75 FR 39839 - Regulated Navigation Area; Hudson River and Port of NY/NJ

    Science.gov (United States)

    2010-07-13

    ... restrictions with the Kiewit and Weeks Marine contractors, and with Hudson River and Sandy Hook Pilots... transfer of the bridge span from shore to the barges has been scheduled on a weekday when it is expected to... Overtaking zones are established in areas identified by Weeks Marine, Hudson River and Sandy Hook Pilots as...

  2. EnviroAtlas - Paterson, NJ - One Meter Resolution Urban Land Cover Data (2010)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Paterson, New Jersey EnviroAtlas One Meter-scale Urban Land Cover data comprises approximately 66 km2 around the city of Paterson. The land cover data were...

  3. 78 FR 11097 - Artificial Island Anchorage No. 2 Partial Closure, Delaware River; Salem, NJ

    Science.gov (United States)

    2013-02-15

    ... Administrative Procedure Act (APA) (5 U.S.C. 553(b)). This provision authorizes an agency to issue a rule without... follows: PART 165--REGULATED NAVIGATION AREAS AND LIMITED ACCESS AREAS 0 1. The authority citation...

  4. 75 FR 68704 - Drawbridge Operation Regulations; Hackensack River, Jersey City, NJ

    Science.gov (United States)

    2010-11-09

    ... District, has issued a temporary deviation from the regulation governing the operation of the Upper Hack...-9826. SUPPLEMENTARY INFORMATION: The Upper Hack Bridge, across the Hackensack River at mile 6.9 has a... the bridge. Under this temporary deviation the Upper Hack Bridge, mile 6.9, across the...

  5. 76 FR 50123 - Drawbridge Operation Regulations; Hackensack River, Jersey City, NJ

    Science.gov (United States)

    2011-08-12

    ... of the Hack Freight Bridge, mile 3.1, across the Hackensack River, at Jersey City, New Jersey. The... Operations, telephone 202-366-9826. SUPPLEMENTARY INFORMATION: The Hack Freight Bridge, across the Hackensack... bridge of equipment in order to provide openings. Under this temporary deviation the Hack Freight...

  6. 76 FR 4818 - Drawbridge Operation Regulations; Hackensack River, Jersey City, NJ

    Science.gov (United States)

    2011-01-27

    ... of the Upper Hack Bridge across the Hackensack River, mile 6.9, at Secaucus, New Jersey. The..., Program Manager, Docket Operations, telephone 202-366-9826. SUPPLEMENTARY INFORMATION: The Upper Hack... necessary electrical system upgrades at the bridge. Under this temporary deviation the Upper Hack...

  7. 76 FR 9224 - Drawbridge Operation Regulations; Hackensack River, Jersey City, NJ

    Science.gov (United States)

    2011-02-17

    ... of the Lower Hack Bridge across the Hackensack River, mile 3.4, at Jersey City, New Jersey. The.... SUPPLEMENTARY INFORMATION: The Lower Hack Bridge, across the Hackensack River at mile 3.4, has a vertical... necessary structural steel repairs at the bridge. ] Under this temporary deviation the Lower Hack...

  8. 76 FR 27250 - Drawbridge Operation Regulations; Hackensack River, Jersey City, NJ

    Science.gov (United States)

    2011-05-11

    ... of the Lower Hack Bridge across the Hackensack River, mile 3.4, at Jersey City, New Jersey. The.... SUPPLEMENTARY INFORMATION: The Lower Hack Bridge, across the Hackensack River at mile 3.4, has a vertical... Lower Hack Bridge, across the Hackensack River at mile 3.4, may remain in the closed position from 10...

  9. Multi-biomarker Characterization of Sedimentary Organic Carbon along the Mullica River, NJ

    Science.gov (United States)

    Medeiros, P. M.; Sikes, E. L.

    2007-05-01

    Located in southeastern New Jersey, the Mullica River is approximately 90 km long, extending from the Indian Mills headwaters, through the Pinelands National Reserve to the Great Bay Estuary. The land cover vegetation of the Mullica River watershed (~ 1700 km2) encompasses pine-oak forests (50%) predominantly in the Pinelands followed by wetlands (36%) especially towards the estuary, representing one of the most pristine areas in the state. Sources and potential transformations of sedimentary organic carbon along the Mullica River were assessed using a natural multi-biomarker approach. Sediment samples were collected from the Pinelands to the bay and analyzed as silylated total extracts by gas chromatography-mass spectrometry. The primary biomarker classes found in the samples included n-alkanoic acids, n-alkanols, phytosterols, triterpenoids and saccharides. In general, sediment extracts composition reflected changes in the characteristic main cover vegetation along the river. The major biomarker contributions in the Pinelands sediments were phytosterols (sitosterol, stigmasterol, campesterol), their reduced products (i.e., stigmastanol, campestanol) and triterpenoids (β-amyrin, oleanoic acid) derived from higher plants detritus, followed by n-alkanoic acids and n- alkanols from epicuticular plant wax. Diterpenoids, mainly dehydroabietic acid (a biomarker for conifers), as well as the monosaccharide glucose and the fatty acids 16:0, 16:1, 18:0, 18:1, 18:2 (ubiquitous in biota) were important organic tracers observed in these sediments. The higher plants biomarkers tended to decrease downstream to trace levels in the bay extracts. An exception was the triterpenoid taraxerol (previously identified as a mangrove biomarker) derived mainly from the salt marsh vegetation draining the Great Bay. The higher abundances of the low molecular weight fatty acids (< C19) observed in the estuarine sediments are likely derived from marine phytoplanktonic inputs.

  10. 3 nj-symbols and harmonic superposition coefficients: an icosahedral abacus

    Science.gov (United States)

    Aquilanti, Vincenzo; Coletti, Cecilia

    2001-08-01

    Angular momentum recoupling coefficients of angular momentum theory and matrix elements for basis set transformation of hyperspherical harmonics enjoy properties and sum rules crucial for applications but complicated without the guidance of graphical techniques. These coefficients being related to Racah's polynomials, the graphs also apply to polynomials of the hypergeometric family, their q-analogues and their `elliptic' extensions. A useful `abacus' exploiting the connections with presentations of icosahedral and related symmetries is introduced. Particular and limiting cases, such as those of the semiclassical type, allow a unified view of properties of angular and hyperangular momentum algebra, including relationships among vector coupling coefficients and rotation matrix elements.

  11. 77 FR 26737 - Foreign-Trade Zone 235-Lakewood, NJ: Notification of Proposed Production Activity; Cosmetic...

    Science.gov (United States)

    2012-05-07

    ... blending and bottling of fragrances. Components and materials sourced from abroad include: plastic bottles; glass bottles; plastic caps and lids; metal caps and lids; plastic collars; sprayers; pumps; and... bottles of fragrance (duty-free) for the foreign status inputs noted above. Customs duties also...

  12. 76 FR 52569 - Regulated Navigation Area; Arthur Kill, NY and NJ

    Science.gov (United States)

    2011-08-23

    ... channel, require the relocation of lateral aids to navigation, and create a reduction in the width of the.... If you think that your business, organization, or governmental jurisdiction qualifies as a small... ADDRESSES) explaining why you think it qualifies and how and to what degree this rule would...

  13. 76 FR 80885 - Foreign-Trade Zone 44-Morris County, NJ; Application for Expansion

    Science.gov (United States)

    2011-12-27

    ... on a case-by-case basis. In accordance with the Board's regulations, Kathleen Boyce of the FTZ Staff..., contact Kathleen Boyce at Kathleen.Boyce@trade.gov or (202) 482-1346. Dated: December 20, 2011. Andrew...

  14. 78 FR 57567 - Safety Zone; Military Munitions Recovery, Raritan River, Raritan, NJ

    Science.gov (United States)

    2013-09-19

    ... District Waterways Management Branch, telephone (617) 223-8381, email craig.d.lapeijko@uscg.mil . If you... radio or loudhailer. (2) ``Official patrol vessel'' means any Coast Guard, Coast Guard Auxiliary, Army... siren, radio, flashing light, or other means, the operator of a vessel shall proceed as directed....

  15. EnviroAtlas - Paterson, NJ - Estimated Percent Green Space Along Walkable Roads

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset estimates green space along walkable roads. Green space within 25 meters of the road centerline is included and the percentage is based on...

  16. EnviroAtlas - Paterson, NJ - Potential Window Views of Water by Block Group

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset describes the block group population and the percentage of the block group population that has potential views of water bodies. A potential...

  17. 2012 USGS EAARL-B Coastal Topography: Post-Sandy, First Surface (NJ)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — ASCII xyz and binary point-cloud data, as well as a digital elevation model (DEM) of a portion of the New Jersey coastline, pre- and post-Hurricane Sandy (October...

  18. EnviroAtlas - Paterson, NJ - Greenspace Around Schools by Block Group

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas data set shows the number of schools in each block group in the EnviroAtlas community boundary as well as the number of schools where less than 25%...

  19. 75 FR 27507 - Safety Zone; Delaware River, Big Timber Creek, Westville, NJ

    Science.gov (United States)

    2010-05-17

    ... expect the economic impact of this proposed rule to be so minimal that a full Regulatory Evaluation is... made to the maritime community via marine information broadcasts and area newspapers so mariners can... is intended to temporarily restrict vessel traffic in the regulated area within Big Timber...

  20. 76 FR 77769 - Foreign-Trade Zone 49-Newark/Elizabeth, NJ; Application for Expansion

    Science.gov (United States)

    2011-12-14

    ... (145 acres) and adjacent 53-acre Greenville Industrial Park on Upper New York Bay's Port Jersey Channel in Bayonne and Jersey City; Site 5 (40 acres)--Newark International Airport jet fuel storage and... copy of the application will be available for public inspection at the Office of the...

  1. 77 FR 1023 - Regulated Navigation Area; Arthur Kill, NY and NJ

    Science.gov (United States)

    2012-01-09

    .... If you submit comments by mail or hand delivery, submit them in an unbound format, no larger than 8\\1... meaning of the Administrative Procedure Act (APA), 5 U.S.C. 553. But you may submit a request for one..., under the authority of the Administrative Procedure Act (APA), 5 U.S.C. 553(b), and giving effect to it...

  2. EnviroAtlas - Paterson, NJ - Historic Places by Census Block Group

    Data.gov (United States)

    U.S. Environmental Protection Agency — This EnviroAtlas dataset portrays the total number of historic places located within each Census Block Group (CBG). The historic places data were compiled from the...

  3. 78 FR 53104 - Drawbridge Operation Regulation; Hackensack River, Kearny and Jersey City, NJ

    Science.gov (United States)

    2013-08-28

    ... that, the draw need not open for the passage of vessel traffic between 6 a.m. and 10 a.m. and 2 p.m... Activities The Coast Guard respects the First Amendment rights of protesters. Protesters are asked to contact..., Governmental Actions and Interference with Constitutionally Protected Property Rights. 9. Civil Justice Reform...

  4. 78 FR 53107 - Drawbridge Operation Regulation; Passaic River, Kearny and Newark, NJ

    Science.gov (United States)

    2013-08-28

    ... that, the draw need not open for the passage of vessel traffic between 6 a.m. and 10 a.m. and 2 p.m... Guard respects the First Amendment rights of protesters. Protesters are asked to contact the person... Interference with Constitutionally Protected Property Rights. 9. Civil Justice Reform This proposed rule meets...

  5. Screening and optimization of EPA-producing antarctic psychrophilic bacterium Shewanella sp.NJ136

    Institute of Scientific and Technical Information of China (English)

    Zhang Botao; Miao Jinlai; Ma Jinhai; Zheng Zhou; Wang Guodong; Wang Quanfu; Li Guangyou; Liu Wanshun

    2007-01-01

    Two hundred strains of bacteria from Antarctic sea ice were collected and screened for their ability of producing eicosapentaenoic acid(EPA, 20:5ω3)by means of Gas Chromatography/Mass Spetrometry (GC/MS). Eight strains of bacteria containing EPA were investigated, among which the outstanding one was recorded as NJl36. This bacterium was identified as Shewanella by the biochemical characteristics and 16S rRNA sequence. Response surface methodology(RSM)was applied to optimize the medium ingredients. A 24full factorial central composite design(FFCCD)was employed to determine the maximum EPA production at optimum levels of pH, NaCl, glucose and yeast extract. The predicted optimal combination of media constituents for maximum 14.02 mg/g(about 1.7-fold increase)EPA production were determined as 30.15‰(m/v)NaCl, 9.98g/L glucose, 4.42g/L yeast extract and pH 6.08. The actual experimental results were in agreement with the prediction.

  6. Journal of Agricultural Extension http://dx.doi.org/10.4314.jae.v19i1 ...

    African Journals Online (AJOL)

    User

    2003) and the Market Propelled or Induced Model (Roling, 2010; Roling et al., ... participatory approaches such as the Participatory Technology Development .... formed by many agents of different types, where each defines his/her strategy, ..... The farm must be equipped with basic logistics such as first aid box, protective.

  7. Tasiame et al., Afr. J. Infect. Dis. (2016) 10 (1): 55 – 57 http://dx.doi ...

    African Journals Online (AJOL)

    Proff.Adewunmi

    56% of which occur in Asia and 44% in Africa, particularly in rural areas on both continents, where dogs .... Rabies in Ghana, West Africa, International Journal of Zoonoses 11(1): 53-58. ... Asian Pacific Journal of Tropical Disease 5 (1): 17-21.

  8. http://dx.doi.org/10.4314/jae.v18i1.13 Adoption of Rice Technologies ...

    African Journals Online (AJOL)

    PROF. MADUKWE

    marketing technologies introduced by the project were determined. To achieve this .... mix application (2 litres/ha) had mean adoption score of 1.54. Further ... that what farmers produced are marketed at right time and at better price, is yet to be.

  9. Kitara et al., Afr. J. Infect. Dis. (2013) 7(2): 36 – 43 http://dx.doi.org ...

    African Journals Online (AJOL)

    cadewumi

    child miss school and also develop emotional stress making them present with inappropriate behaviours .... product moment correlation coefficient was used to determine the relationships, the ..... and Sports for UNICEF, Kampala, Uganda. 16.

  10. Journal of Agricultural Extension http://dx.doi.org/10.4314/jae.v18i2 ...

    African Journals Online (AJOL)

    PROF. MADUKWE

    knowledge-sharing (M= 2.5), and improved farmer-to-farmer networking (M ... contact and poor health status of farmers (M = 2.7 respectively), and rural- ... labour group is an assemblage of two or more human beings with common identity who.

  11. Journal of Agricultural Extension http://dx.doi.org/10.4314.jae.v19i1 ...

    African Journals Online (AJOL)

    User

    Assessment of Food Security Situation of Tiv Farming households in Nigeria. Dooshima P Ivanda1 ... huge endowed natural and human resources is not spared. Nigerian environment is ..... Improved health facilities. 1.45. 0.714. Increased ...

  12. Journal of Agricultural Extension http://dx.doi.org/10.4314.jae.v19i1 ...

    African Journals Online (AJOL)

    User

    This study assessed awareness and use of information and communication ... It is an interactive process that works in a circular, dynamic and ongoing way. ... For agricultural extension in Nigeria to be effective extension personnel, must.

  13. Journal of Agricultural Extension http://dx.doi.org/10.4314/jae.v18i2 ...

    African Journals Online (AJOL)

    PROF. MADUKWE

    Urban Farmers' Adoption of Improved Dry Season Vegetable Production ... techniques, practices and innovations used to maximize agricultural production. ..... and urban planning implications of Katsina Metroplis, Nigeria, African Journal of.

  14. http://dx.doi.org/10.4314/agrosh.v16i2.7 EFFECTS OF FOOD ...

    African Journals Online (AJOL)

    Ifedotun Aina

    Department of Home Economics and Food Sciences. Faculty of ... The Science of Food and Nutrition ..... Warankashi, a traditional cheese, Croatian Journal of Food Science Technology. 8(1):10. ... Is there a culinary skills transition? Data and ...

  15. 新一代基因测序平台MiSeqDxTM首获FDA临床认证

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    Illumina公司近日宣布,MiSeqDx台式新一代测序仪及配套试剂盒已通过美国FDA审批,可用于临床分子诊断应用,成为全球首个且是目前唯一一个获得FDA临床认证的新一代测序(NGS)平台。

  16. http://dx.doi.org/10.4314/jae.v18i1.6 Factors Influencing the ...

    African Journals Online (AJOL)

    PROF. MADUKWE

    The study assessed the adoption of Sasakawa Global 2000 maize production practices ... The result further shows that age, education, household size, extension contact, farm ..... Sociology, Faculty of Agriculture, Ahmadu Bello University,Zaria.

  17. Kra et al., Afr. J. Infect. Dis. (2016) 10 (1): 43–48 http://dx.doi.org ...

    African Journals Online (AJOL)

    Proff.Adewunmi

    A previous training was conducted on BEAs for 67.3% of nursing students. ... preventive measures in view of reducing their incidence. ... and build the capacity of health workers as well as conduct research in nursing care and biotechnology.

  18. Journal of Agricultural Extension http://dx.doi.org/10.4314/jae.v18i2 ...

    African Journals Online (AJOL)

    PROF. MADUKWE

    Department of Agricultural Extension and Rural Development, University of Ibadan,. Ibadan ... information was family members and radio and not through extension agents. ... Nigeria, China, Syria, Guinea, Japan, Saudi Arabia, India, Sierra.

  19. 亚马逊 Kindle DX 支持PDF格式、辅助阅读功能

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    亚马逊发布了其新款电子书阅读器Kindle DX,它是目前为止最大的Kindle阅读器,其屏幕尺寸达到了917英寸,分辨率为1200×824像素,屏幕采用e—ink技术。与前代产品Kindle和Kindle2相比,Kindle DX支持PDF文件格式,可以存放最多3500本书籍。

  20. Desarrollo de un videojuego para móviles con Unity o Cocos2d-x

    OpenAIRE

    Egea Canales, José María

    2016-01-01

    Los dispositivos móviles se han convertido en una de las principales plataformas para videojuegos. Una de las principales problemáticas al desarrollar aplicaciones para estos dispositivos es la alta fragmentación que existe en cuanto a sistemas operativos y características de la interfaz. Existen determinadas librerías y herramientas como Unity 3D dirigidas a resolver este problema, permitiendo desarrollar videojuegos que puedan ser portados a las principales plataformas móviles existentes....

  1. Animasahun et al., Afr. J. Infect. Dis. (2013) 7(1): 11 – 13 http://dx.doi ...

    African Journals Online (AJOL)

    AJTCAM

    Eosinophilic meningitis is rare, commonly caused by invasion of the central nervous system by helminthes. ... Initial diagnostic considerations included transverse myelitis, Potts disease, poliomyelitis and Gullain Barre ... for ova and parasite. ... It is acquired by eating undercooked or raw fish, frog, bird, or snake meat.

  2. Journal of Agricultural Extension http://dx.doi.org/10.4314.jae.v19i1 ...

    African Journals Online (AJOL)

    User

    area influence their level of use of ICT. ... support for specific development projects and social services, raising people's awareness of ..... business; it enhances marketing of agricultural products through strengthening social networks and.

  3. Kitara et al., Afr. J. Infect. Dis. (2015) 9(2): 21 – 28 http://dx.doi.org ...

    African Journals Online (AJOL)

    Proff.Adewunmi

    This study therefore provided the basic information regarding the condition of ..... partners and poor health seeking behavior leading to delay in HIV diagnosis and initiation on .... WHO Library cataloguing-in-publication data of 2013 Geneva,.

  4. Journal of Agricultural Extension http://dx.doi.org/10.4314.jae.v19i1 ...

    African Journals Online (AJOL)

    User

    http://www.ajol.info/index.php/jae. 57 ... Studies on stakeholders' perception on input subsidy initiatives in Nigeria show that fertilizer quality ... targeted farmers because of the corruption that shrouded the procurement and delivery system.

  5. http://dx.doi.org/10.4314/jae.v18i1.14 Level of Utilization of ...

    African Journals Online (AJOL)

    PROF. MADUKWE

    orthodox medicine and the factors influencing the use of medicines. .... source of livelihood is agriculture and rural areas serve as the major sources of food for .... dwellers had formal education which may affect people's choice of medicine and .... fast recovery is a very important determinant of the use of Primary Health Care.

  6. Journal of Agricultural Extension http://dx.doi.org/10.4314.jae.v19i1 ...

    African Journals Online (AJOL)

    User

    Consumer Association, 2008; Integrated Regional Information Network, 2008). ... However, the adoption of agrochemical should go beyond just measuring the ..... These were labels which advised users to protect their eyes, put on boots,.

  7. http://dx.doi.org/10.4314/jae.v18i1.5 Socio-Economic Factors ...

    African Journals Online (AJOL)

    PROF. MADUKWE

    The general objective of the study is to analyze the socio economic factors that influence ..... adopt a technology learnt by farmers especially in the case of an input – intensive innovation .... Association, July 27 – 29 Orlando Florida, USA.

  8. http://dx.doi.org/10.4314/jae.v18i1.3 Women Farmers' Perception ...

    African Journals Online (AJOL)

    PROF. MADUKWE

    effective integration of information and communications technologies (ICTs) in different ... and the market prices of farm inputs and outputs is fundamental to ..... Forestry Policy network (PAFPNet), Land Resources Division News Article,.

  9. Journal of Agricultural Extension http://dx.doi.org/10.4314.jae.v19i1 ...

    African Journals Online (AJOL)

    User

    Agriculture and Natural Resources Policy Analysis Network (FANRPAN) .... questions relating to farm problems with the advantages of getting feedback. ... drivers of social and economic transformation in the world, they play a critical role in the.

  10. Journal of Agricultural Extension http://dx.doi.org/10.4314.jae.v19i1 ...

    African Journals Online (AJOL)

    User

    Determinants of Adoption of Cassava Technologies by Male Farmers in Nasarawa ... It has become the most important root crop in tropical Africa providing food for over ..... Evaluation of the effect of agricultural extension delivery in cassava.

  11. Active 46-year-old man with right-sided visual loss and no family history of stroke · Dx?

    Science.gov (United States)

    Ajayi, Tokunbo; Yang, Hyun-Sik; Bhatia, Ashmeet

    2017-08-01

    A 46-year-old man presented to the emergency department with sudden-onset right-sided visual loss. He had a history of asthma, but no family history of hypercoagulability, deep vein thrombosis, or stroke. The patient had an active lifestyle that included scuba diving, mountain biking, and hockey (coaching and playing). The physical examination revealed a right homonymous upper quadrantanopia. The neurologic examination was within normal limits, except for the visual deficit and unequal pupil size. A computerized tomography scan of the patient's head did not reveal any lesions.

  12. http://dx.doi.org/10.4314/jae.v18i1.7 Climate Change Information ...

    African Journals Online (AJOL)

    PROF. MADUKWE

    Climate Change Information Needs of Pineapple Farmers in Enugu State, Nigeria ... shifting, glaciers and snow are melting, and the global mean sea level is rising. It is .... farmers generally into non- farm occupations may lead to extinction of ...

  13. doi: http://dx.doi.org/10.4314/ejesm.v10i1.1 De

    African Journals Online (AJOL)

    USER

    2017-01-16

    Jan 16, 2017 ... For the few REIT companies listed on the SE, the share prices ... and even Malaysia at 33% at that moment. .... the properties involved in the property ... Nonetheless, there still was political ... Social Democratic Party ('SPD').

  14. Firm, non-tender mass in right breast · worsening, nonproductive cough · pleuritic pain · Dx?

    Science.gov (United States)

    Lehman, Trang D; Damania, Zubin; Tschetter, Clifford N; Lehman, Norman L

    2017-01-01

    Granulomatous lesions, such as foreign body granuloma, idiopathic granulomatous mastitis (IGM), and sarcoidosis can mimic breast carcinoma. IGM is associated with elevated prolactin (eg, pregnancy or oral contraceptive use) and is usually subareolar. Infection, however, is also commonly subareolar.

  15. Journal of Agricultural Extension http://dx.doi.org/10.4314.jae.v19i1 ...

    African Journals Online (AJOL)

    User

    The study examined backyard banana and plantain production among households ..... practices is highly important for increase and sustained production. .... increases as the distance from the homestead increases particularly in acid soil.

  16. Electrical Behavior on N-Type Dopants in AlGaAs Alloys: Shallow Levels and DX Centers

    Science.gov (United States)

    1990-11-01

    FORCE OFFICE OF SCIENTIFIC RESEARCH GRANT AFOSR-88-0316 EOSRD-LONDON DEPARTAMENTO DE INGENIERIA ELECTRONICA E.T.S. INGENIEROS DE TELECOMUNICACION...PERSONNEL : ENRIQUE CALLEJA IGNACIO IZPURA FERNANDO GARCIA ANGEL L. ROMERO UNIVERSIDAD POLITECNICA DE MADRID DEPARTAMENTO DE INGENIERIA ELECTRONICA ETS

  17. 新版手持式三维激光扫描仪FARO Scanner Freestyle 3D DX

    Institute of Scientific and Technical Information of China (English)

    2016-01-01

    Freestyle 3D X采用最先进的扫描技术。使1m范围内的扫描精度提高到1mm。Freestyle 3D X采用美国国家标准与技术研究院的可追踪校准附件为用户提供可验证的数据精确度,这对取证扫描和其他受到严格监管的行业来说是非常关键的。

  18. Etuketu et al., Afr. J. Infect. Dis. (2015) 9(2): 51 – 56 http://dx.doi.org ...

    African Journals Online (AJOL)

    Proff.Adewunmi

    However, measures geared towards promoting prevention ... little or no attention in clinical practice and STI control efforts (WHO, 2001). .... country. Trichomoniasis is believed to be transmitted usually through unprotected sexual intercourse, ...

  19. Journal of Agricultural Extension http://dx.doi.org/10.4314/jae.v18i2 ...

    African Journals Online (AJOL)

    PROF. MADUKWE

    /staff communication (M= 3.56), monitoring and evaluation system (M= 3.32), ... success recorded by the small scale irrigation projects carried out by the ..... packages which provides for staff interaction, communication, motivation and role .... engaging in religious activities and good social relation are often useful behavior in.

  20. Journal of Agricultural Extension http://dx.doi.org/10.4314/jae.v18i2 ...

    African Journals Online (AJOL)

    PROF. MADUKWE

    The study characterized Bauchi State sesame value chain development ... marketing problems (M = 2.52) and lack of access to credit facility (M = 2.40). .... type scale of to a very great extent =4, great extent=3, to some extent,=2 and to no .... 2.40), inability to access government assistance (M = 2.36), untimely supply of farm.

  1. http://dx.doi.org/10.4314/jae.v18i1.9 Gender Dimension to Farmers ...

    African Journals Online (AJOL)

    PROF. MADUKWE

    Gender Dimension to Farmers' Perception of the National Fadama Development .... Meanwhile Fadama III was equipped with measures to correct the ... 3. determine the attitude of beneficiaries to the Fadama III Project by gender; and .... Carrying out needs assessment. 2.18 ... Plan for training/building the capacity of FCAs.

  2. http://dx.doi.org/10.4314/jae.v18i1.10 Private Sponsorship of Rural ...

    African Journals Online (AJOL)

    PROF. MADUKWE

    Private Sponsorship of Rural Development Broadcasts on Radio in Southwest. Nigeria. Badiru ... +2348034660732. E-mail: bodebadru@yahoo.com ... by a government agency, in comparison with sport and entertainment broadcasts which ...

  3. Journal of Agricultural Extension http://dx.doi.org/10.4314/jae.v18i2 ...

    African Journals Online (AJOL)

    PROF. MADUKWE

    recently there have been changes in the structure of the forestry sector in Nigeria. ... recorded in vegetation, forest complexity (diversity), or in germplasm (quality). The ... the state governments (Status of tropical forest management, 2005).

  4. Excitation functions of (d,x) nuclear reactions on natural titanium up to 24 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Khandaker, Mayeen Uddin, E-mail: mu_khandaker@yahoo.com [Department of Physics, University of Malaya, 50603 Kuala Lumpur (Malaysia); Haba, Hiromitsu; Kanaya, Jumpei [Nishina Center for Accelerator-based Science, RIKEN, Wako, Saitama 351-0198 (Japan); Otuka, Naohiko [Nuclear Data Section, Division of Physical and Chemical Sciences, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, A-1400 Vienna (Austria)

    2013-02-01

    Excitation functions of the {sup nat}Ti(d,x){sup 48}V and {sup nat}Ti(d,x){sup 43,44m,44g,46,47,48}Sc nuclear reactions were measured up to a 24-MeV deuteron energy by using a stacked-foil activation technique combined with γ-ray spectrometry with a high-purity germanium detector at the AVF cyclotron of the RIKEN RI Beam Factory, Wako, Japan. An overall good agreement is found between the measured cross-sections and the literature ones, whereas partial agreements are obtained for the theoretical calculations based on the TALYS code. Physical thick target yields, i.e., induced radioactivities per unit fluence of the 24-MeV deuteron were also deduced, and they were compared with the directly measured ones in the literature. The present results will have an important role in enrichment of the literature database of the deuteron-induced reactions on natural titanium leading to various applications.

  5. http://dx.doi.org/10.4314/jae.v18i1.2 Comparison of use of ...

    African Journals Online (AJOL)

    PROF. MADUKWE

    Agricultural Researchers and Extension Personnel in Nigeria. Yekinni, O. T. and Akinbile, ... while the only research stations in each of South-East and North-East zones were selected. ... as well as preserve the natural resources (Islam, 2007). Moreover, the ..... Towards evidence-based ICT policy and regulation: E-. Skills.

  6. NJ1型交流传动内燃调车机车电机组的研制%Development of motor group for NJ1 AC transmission diesel shunting locomotive

    Institute of Scientific and Technical Information of China (English)

    姚陶生

    2001-01-01

    介绍了交流传动内燃调车机车电机组的应用要求、技术特点、主要工艺结构、运用效果及研制方面的经验,提出了其它功率等级的交流传动内燃机车主辅传动系统电机组技术方案建议.

  7. N.J. Bucks Tide on Reading for English-Learners: State Cites Studies Finding Advantage for Bilingual Approach

    Science.gov (United States)

    Zehr, Mary Ann

    2007-01-01

    Taking a position that is unusual these days, New Jersey officials are promoting research that says bilingual education methods have an edge over English-only methods in teaching English-language learners to read. This article talks about the importance of bilingual education or a blended approach in the implementation of Reading First Program in…

  8. 77 FR 69761 - Regulated Navigation Area; Recovery Operations, the Port of New York and New Jersey, NJ and NY

    Science.gov (United States)

    2012-11-21

    ... waterway users, the public, and pollution response and recovery workers for the duration of the response... vessels could pose significant risk of injury or death to response and recovery workers. Certain portions... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA11 Regulated Navigation Area; Recovery Operations, the...

  9. EnviroAtlas - Paterson, NJ - Domestic Water Use per Day by U.S. Census Block Group

    Data.gov (United States)

    U.S. Environmental Protection Agency — As included in the EnviroAtlas, the community level domestic water use is calculated using locally available water use data per capita in gallons of water per day...

  10. Space manufacturing 1983; Proceedings of the Sixth Conference, Princeton University, Princeton, NJ, May 9-12, 1983

    Science.gov (United States)

    Burke, J. D. (Editor); Whitt, A. S. (Editor)

    1983-01-01

    General topics are biomedical and social sciences, space stations and habitats, space manufacturing, international and legal considerations, materials resources and processing, accelerators and asteroids, and space economics. Among the papers presented, consideration is given to the evolution of man as an explorer; whether people, robots, or hybrids should operate a space station; electrophoresis experiments in space; the emerging government regulation of American space entrepeneurs; the extraction and purification of iron-group and precious metals from asteroidal feedstocks; the construction, testing, and design comparison to computer simulation fo the Mass-Driver III; and the international competition in commercial aerospace markets.

  11. Space manufacturing III; Proceedings of the Fourth Conference, Princeton University, Princeton, N.J., May 14-17, 1979

    Science.gov (United States)

    Grey, J. (Editor); Krop, C.

    1979-01-01

    Papers are presented on the various technological, political, economic, environmental and social aspects of large manufacturing facilities in space. Specific topics include the potential global market for satellite solar power stations in 2025, the electrostatic separation of lunar soil, methods for extraterrestrial materials processing, the socio-political status of efforts toward the development of space manufacturing facilities, the financing of space industrialization, the optimization of space manufacturing systems, the design and project status of Mass Driver Two, and the use of laser-boosted lighter-than-air-vehicles as heavy-lift launch vehicles. Attention is also given to systems integration in the development of controlled ecological life support systems, the design of a space manufacturing facility to use lunar materials, high performance solar sails, the environmental effects of the satellite power system reference design, the guidance, trajectory and capture of lunar materials ejected from the moon by mass driver, the relative design merits of zero-gravity and one-gravity space environments, consciousness alteration in space and the prospecting and retrieval of asteroids.

  12. 2007 USGS/NASA Experimental Advanced Airborne Research Lidar (EAARL): Fire Island National Seashore, NY and Sandy Hook, NJ

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — ASCII xyz point cloud data were produced from remotely sensed, geographically referenced elevation measurements cooperatively by the U.S. Geological Survey (USGS)...

  13. DOE Zero Energy Ready Home Case Study: John Hubert Associates — EXIT-0 House, North Cape May, NJ

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2014-09-01

    This house is the first DOE Zero Energy Ready Home for this builder and won a Custom Builder award in the 2014 Housing Innovation Awards. The 1,871-ft2 home features advanced-framed above-grade walls with R-21 fiberglass batt plus an R-3.6-insulated coated OSB sheathing, R-18 rigid-foam-insulated crawlspace walls, solar water heating, a high-efficiency heat pump, an HRV, and mostly LED lighting.

  14. Comparison of kriging and cokriging for the geostatistical estimation of specific capacity in the Newark Basin (NJ) aquifer system.

    Science.gov (United States)

    Carter, Gail P; Miskewitz, Robert J; Isukapalli, Sastry; Mun, Yuri; Vyas, Vikram; Yoon, Sungwon; Georgeopoulos, Panos; Uchrin, Christopher G

    2011-01-01

    Groundwater is a major water source in New Jersey; hence, accurate hydrogeologic data are extremely important. However, most measured data have inadequate spatial density and their locations are often clustered. Our study focuses on implementing geostatistical methods to generate the spatial distribution of specific capacity over the Newark Basin in New Jersey. Two geostatistical methods, ordinary kriging and cokriging, were employed and compared. Ordinary kriging was employed to estimate the spatial distribution of specific capacity by using measured values. Cokriging incorporated the spatial variability of fracture density into the estimation with the spatial variability of specific capacity, as groundwater flow in fractured rock aquifers depends on the fracture characteristics in the Newark Basin. Results indicate that cokriging manifested substantial improvements over ordinary kriging including a larger areal coverage, a more detailed variation of specific capacity, and reduction in the variance of its estimates.

  15. Proceedings of the Tri-Service Gun Tube Wear and Erosion Symposium, ARRADCOM, Dover, NJ, 29-31 March 1977

    Science.gov (United States)

    1977-03-01

    sequently released when the fibers were dissolved to form the lacquer in the hardening process. The presence of acidic materials in the finished...introduced a rifle-type ablative ammunition employing beeswax as the ablator in 1948 with some success but it was not until the last 10 years that...elevated temperatures, as elemental hafnium and columbium oxidize preferentially. The Hf2 then dissolves in the columbium oxide Cb 0 to form 611f0-Cb2 0

  16. 78 FR 11099 - Safety Zone Within the Lower Portion of Anchorage #9, Mantua Creek Anchorage; Paulsboro, NJ

    Science.gov (United States)

    2013-02-15

    ... opportunity to comment pursuant to authority under section 4(a) of the Administrative Procedure Act (APA) (5 U... authority citation for part 165 continues to read as follows: Authority: 33 U.S.C 1231; 46 U.S.C....

  17. Endocrine indicators of a stress response in nesting diamondback terrapins to shoreline barriers in Barnegat Bay, NJ.

    Science.gov (United States)

    Winters, Julianne M; Carruth, Wade C; Spotila, James R; Rostal, David C; Avery, Harold W

    2016-09-01

    Anthropogenic stressors such as habitat loss are a global problem for wildlife. Coastal development in the United States has replaced estuary shorelines with hard erosion barriers. In Barnegat Bay, New Jersey, the diamondback terrapin (Malaclemys terrapin) encounters these barriers when approaching upland beaches for nesting. To determine the effects of shoreline barriers on this threatened species' nesting abilities, we measured adrenocortical response (i.e., stress response) by comparing natural corticosterone and testosterone levels of 91 terrapins following in situ exposure to either an experimentally blocked, or open nesting beach. In addition, we exposed 15 individuals, from various nesting beaches, to handling stress to identify acute corticosterone secretion, finding a significant increase over 60min to 8ng/ml. Corticosterone did not reach this level in terrapins exposed to barriers. Corticosterone and testosterone levels were not significantly higher among terrapins exposed to barriers compared to those at open reference beaches. This lack of a stress response suggests that terrapins do not physiologically respond to barriers when they approach nesting beaches and thus are not stressed. This may be due to an adaptive trait to help female turtles complete the nesting process despite the natural stresses inherent to coming on land. Our study suggests that this lack of stress response is also applied to non-natural, human made nesting barriers. If terrapins are not physiologically capable of adapting to shoreline barriers, future erosion control structures could support terrapin nesting with periodic upland access points. This endocrinological study provides a more quantitative approach to guiding management of anthropogenic stressors upon wildlife.

  18. Analyses of otoliths from juvenile black sea bass collected from estuaries in SC, FL, NJ, and NY: 2008-2009.

    Data.gov (United States)

    Baruch Institute for Marine and Coastal Sciences, Univ of South Carolina — Snappers/Groupers have traditionally been some of the most desired demersal fishes in the South Atlantic Bight and are the most abundant and diverse group of large...

  19. 77 FR 23221 - Foreign-Trade Zone 200-Mercer County, NJ; Application for Reorganization/Expansion Under...

    Science.gov (United States)

    2012-04-18

    ... with the Board's regulations, Kathleen Boyce of the FTZ Staff is designated examiner to evaluate and... via www.trade.gov/ftz . For further information, contact Kathleen Boyce at Kathleen.Boyce@trade.gov...

  20. The "Camden Syndrome" and the Menace of Suburban Decline: Residential Disinvestment and Its Discontents in Camden County, NJ.

    Science.gov (United States)

    Smith, Neil; Caris, Paul; Wyly, Elvin

    2001-01-01

    Challenges conventional urban theory, which explains suburban decline in terms of who moves in and out, examining literature on the circulation of capital in the built environment. Analyzes the systematic withdrawal of capital from one New Jersey suburb, examining mortgage lending decisions to test the hypothesis that suburban decline cannot be…

  1. Three Permeable Pavements Performances for Priority Metal Pollutants and Metals associated with Deicing Chemicals from Edison Parking Lot, NJ - abstract

    Science.gov (United States)

    The U.S. Environmental Protection Agency constructed a 4000-m2 parking lot in Edison, New Jersey in 2009. The parking lot is surfaced with three permeable pavements [permeable interlocking concrete pavers (PICP), pervious concrete (PC), and porous asphalt (PA)]. Samples of each p...

  2. Three Permeable Pavements Performances for Priority Metal Pollutants and Metals Associated with Deicing Chemicals from Edison Parking Lot, NJ

    Science.gov (United States)

    The U.S. Environmental Protection Agency constructed a 4000-m2 parking lot in Edison, New Jersey in 2009. The parking lot is surfaced with three permeable pavements [permeable interlocking concrete pavers (PICP), pervious concrete (PC), and porous asphalt (PA)]. Samples of each p...

  3. 都市精灵总动员—— HONDA Dio ZX(AF34) VSYAMAHA JOG VS YAMAHA JOG ZRVS SUZUKI Let' s Ⅱ DX

    Institute of Scientific and Technical Information of China (English)

    安李楠; 东子(摄影); 倪巍(摄影助理)

    2006-01-01

    摩托世界并非只属于大型车,微型车同样有自己的天地。其中50毫升的日系二冲程微型踏板车在国内的势头最强,近两年已风靡许多大中城市。现在,这些摩托车中的精灵已拥有自己的俱乐部,自己的玩法,甚至还有自己的改装文化!

  4. Poderemos viver juntos? http://dx.doi.org/10.15601/1983-7631/rt.v3n5p183-188

    Directory of Open Access Journals (Sweden)

    Adilson Schultz

    2011-04-01

    Full Text Available O sociólogo Alain Touraine abre uma instigante pergunta ao tratar da constituição do sujeito na sociedade contemporânea: Poderemos viver juntos? O título do livro é uma pergunta retórica à qual só pode ser dada uma resposta condicionada: poderemos sim, desde que... Ou então: não há outra saída – temos que viver juntos.  Tomado nesses termos, a pergunta de Touraine denuncia uma crise geral do sujeito na sociedade contemporânea, para além da crise ambiental, moral, trabalhista, econômica, etc, ou que qualquer uma de “nossas crises prediletas”, como diz Ignacy Sachs. Sua perspectiva mais bem se enquadra numa crise geral civilizacional, transcendendo condições socioculturais específicas. A pergunta Poderemos viver juntos? é global, e a resposta só pode ser geral

  5. http://dx.doi.org/10.4314/jae.v18i1.1 Role of the Three Tiers of ...

    African Journals Online (AJOL)

    PROF. MADUKWE

    government in the provision of basic infrastructure that encourage rural farmers, processors, marketers, etc to increase productivity and quality of agricultural ..... staff in policy formulation, analysis, as well as strategic planning and ... development through the ADP system and using the commodity value chain approach. The.

  6. Errata Corrige. Orthostatic Reactivity in Patients with Ischemic Stroke in the Chronic Period. http://dx.doi.org/10.3889/oamjms.2015.090

    Directory of Open Access Journals (Sweden)

    Danche Vasileva

    2015-08-01

    CONCLUSION: The applied specialized kinesitherapeutic methodology continued later as an adapted exercise program at home, has significantly improved the orthostatic reactivity in patients with orthostatic dysregulation due to the ISChP.

  7. Evaluation of the Integral ∫−1+1 Plm,n(x)Plm−2,n(x) dx

    NARCIS (Netherlands)

    Brakman, C.M.

    1987-01-01

    Integrals of the type indicated can be evaluated using the Fourier-series development of the Jacobi-polynomials. An alternative procedure is given yielding an analytical expression in terms of l, m and n.

  8. AN ASSESSMENT OF ACADEMIC PRODUCTION OF RECENT BUSINESS CLUSTERS IN BRAZILhttp://dx.doi.org/10.5585/riae.v10i1.1717

    Directory of Open Access Journals (Sweden)

    João Paulo Lara de Siqueira

    2011-06-01

    Full Text Available Researchers often face difficulties when identifying the principal texts and authors in a field of knowledge of interest to them, especially in areas that are not consolidated, as in the case of business clusters. This study’s objective is to identify the most important authors of recent papers on business clusters, in terms of production volume and number of citations, and which international authors play a major influence on the national research in this area. The study was conceived with a sample of the literature of interest constituted by the works presented in the EnANPAD and Semead events, between 1997 and 2008. The bibliometric technique was adopted - a quantitative and statistical method to measure the production and dissemination of scientific knowledge -. Our findings demonstrate that Toledo, Szafir-Goldstein and Câmara are the most published national authors. The researchers having the largest number of citations are Casarotto Filho, Pires, Amato Neto, Toledo and Zaccarelli. International authors possessing a higher number of citations are Michael Porter and others related to the field of economics. The study suggests that the national literature concerned with clusters is more disperse than in other branches of knowledge.

  9. SUSTAINABLE COMPETITIVE ADVANTAGES: AN EXPLORATORY STUDY OF THE BRAZILIAN CELL PHONE SECTORhttp://dx.doi.org/10.5585/riae.v9i2.1674

    Directory of Open Access Journals (Sweden)

    Rodolfo Borges Felipe

    2010-11-01

    Full Text Available In an environment of rapid changes one should seek definitions of what would be the strategic solutions adopted by organizations to ensure a competitive edge. This article is targeted to identify and verify the longevity of potential competitive advantages in Brazil’s mobile telephone sector through the analysis of the strategic actions taken by its operators between 2000 and 2008.  Therefore, a two stage qualitative research with exploratory-descriptive features was adopted and carried out. The first stage saw the development of a theoretical framework based on the theory of competitive advantage. In the second step, the impact of strategic actions with the potential to become a competitive advantage in the four major mobile phone companies in the country was analyzed, and the examination of the sustainability of competitive advantages created from those actions was also undertaken. The study concluded that, although being a highly dynamic and competitive sector, there is evidence of the occurrence of a sustainable competitive advantage in the mobile telephone sector in Brazil.

  10. Clinical procedures used for the analysis of body composition. http://dx.doi.org/10.5007/1980-0037.2013v15n1p113

    Directory of Open Access Journals (Sweden)

    Dartagnan Pinto Guedes

    2013-01-01

    Full Text Available According to the requirement for precision, accuracy and validation of information to be treated, clinical procedures can be characterized as an acceptable and accessible option for the analysis of components associated with body composition. The techniques with clinical features more commonly used are bioelectrical impedance and anthropometry by skinfold thickness. However, despite the greater feasibility in the face of laboratory procedures, clinical procedures have limitations and specifications regarding the use of their protocols, which should necessarily be considered when they are used. The purpose of this review is to provide a critical analysis about the use of bioelectrical impedance and anthropometry and explain the importance of carrying out well defined application standards to ensure more appropriate body composition estimation.

  11. http://dx.doi.org/10.4314/jae.v18i1.4 Adoption of Green River Project ...

    African Journals Online (AJOL)

    PROF. MADUKWE

    farmers do not significantly influence the adoption of improved fish farming technologies. .... Majority (87.5%) of the respondents had contact with GRP personnel ... sources of good water; pond construction such as depth of 75cm- 2m deep; ...

  12. Cartografia da paisagem alterada http://dx.doi.org/10.15601/1983-7631/rt.v3n5p126-134

    Directory of Open Access Journals (Sweden)

    Simone Cortezão

    2011-04-01

    Full Text Available O presente trabalho de pesquisa surge da investigação de paisagens alteradas, áreas pós-industriais e da geografia urbana que é conformada pela indústria. A preocupação principal é revê-las como espaço de investigação crítica sob o ponto de vista particular, integradas às noções da peculiar natureza industrial com suas consequentes transformações na paisagem, além das relações do indivíduo com esse novo meio produzido. “Cartografia da paisagem alterada” é uma pesquisa que indicia a paisagem alterada em pelo menos dois estratos: um que é o da construção da geografia da cidade pela indústria, e o outro que é a paisagem alterada subjetivamente, o que configura uma crítica e uma reação à conformação sócio geográfica em outros parâmetros - da proximidade, da experiência vivida e da construção de um vocabulário próprio.  A pesquisa teórica sobre áreas pós-industriais, associada a referências nas artes e arquitetura, constitui o primeiro estrato. Teorias e procedimentos artísticos de Robert Smithson, Joseph Beuys e Rem Koolhaas fornecem material para o segundo, mediante a pesquisa do cotidiano no lugar, a região do Vale do Aço, que se configura em um guia - glossário.Palavras-chave: Paisagens alteradas; entropia; áreas pós-industriais; Vale do Aço

  13. INTERNATIONALIZATION MOTIVATIONS AND FOREIGN MARKET ENTRY MODEShttp://dx.doi.org/10.5585/riae.v10i1.1719

    Directory of Open Access Journals (Sweden)

    Manuel Aníbal Silva Portugal Vasconcelos Ferreira

    2011-06-01

    Full Text Available The motivations for the internationalization of firms influence the selection of foreign entry modes. In this article we use John Dunning’s (1993 classification, which distinguishes four primary motives to invest overseas – market seeking, resource seeking, strategic asset seeking and efficiency seeking –, conceptually discussing the impact of the selected foreign entry modes. The methods and strategies of multinational corporations (MNCs are chosen in a broader framework, where internationalization motivations converge with the exploitation, or exploration, of firm-specific advantages. Our analysis is supported by a set of theoretical propositions. The results demonstrate that MNCs must develop the best possible combination of strategy-structure for their international operations, and yet conceive a casuistic analysis of each individual operation. We have therefore contributed to a better understanding of the selection of foreign market entry modes as a reflection of strategic choices or motivations.

  14. LA RACIONALIDAD EN LAS DECISIONES ESTRATÉGICAShttp://dx.doi.org/10.5585/riae.v9i1.1653

    Directory of Open Access Journals (Sweden)

    José Emilio Navas López

    2010-07-01

    Full Text Available Este artigo tem por objetivo analisar se o processo de tomada de decisão estratégica é mais ou menos racionais. Em princípio, este processo deverá responder a um sistema de racionalidade estritamente de acordo com a lógica econômica. No entanto, na realidade, este processo não é sempre o caso, aparecendo vários fatores que contribuem para aumentar ou reduzir essa racionalidade. Este artigo propõe, em primeiro lugar, uma decisão estritamente racional estratégico, a partir do qual inferir as principais vantagens e pontos fortes para a adoção das melhores decisões estratégicas. Mais tarde, a crítica, diante desse modelo e explica os fatores que, na prática, depende da maior ou menor racionalidade do processo. A partir dessa comparação, os resultados sustentam a utilização de um processo que começa com as hipóteses de som, embora ciente das diferentes influências internas e externas que afetam o curso das decisões, reduzindo a racionalidade.

  15. DX系列中波发射机功放故障的处理%Power Amplifier Fault Processing of DX Series MW Transmitters

    Institute of Scientific and Technical Information of China (English)

    金庆哲

    2007-01-01

    DX系列中波发射机在播音中,烧功放模块是一种比较常见的故障.本文作者在日常维护工作中,对各种可能引起烧功放故障的原因进行了认真的分析,并结合相关的理论知识及多年的维护工作经验总结出一些比较有效的预防办法及应对措施,对安全播音工作起到了一定作用.

  16. Ballroom dance: chronic responses on blood pressure in medicated hypertensives. http://dx.doi.org/10.5007/1980-0037.2013v15n2p155

    Directory of Open Access Journals (Sweden)

    Fernanda Christina de Souza Guidarini

    2013-03-01

    Full Text Available The importance of physical exercise for patients with systemic hypertension is well established in the literature. However, ballroom dance has been little investigated in this context. The objective of this study was to determine the chronic effect of ballroom dance on blood pressure in medicated hypertensives. The sample was the number of blood pressure measurements obtained during the patients’ participation in the dance program. Thus, 92 blood pressure measurements were taken and divided into four groups: 1 pre-session systolic blood pressure, 2 post-session systolic blood pressure, 3 pre-session diastolic blood pressure, 4 post-session diastolic blood pressure. We used a mercury sphygmomanometer and stethoscope. As measuring protocol, we considered the Brazilian Guidelines. Blood pressure was measured before and after each ballroom dance session. The mean age of the 23 medicated hypertensive patients studied was 62.5 ± 7 years and 34.8% of them were male. Forty sessions were held three times a week, lasting one hour/session. The mean pre-session systolic blood pressure was 131,8 ± 17mmHg and 117,8±13mmHg after the session, with statistically significant difference (p <0.001; in diastolic blood pressure values were 70,7±6mmHg and 67,7±9mmHg (p <0.075. We conclude that ballroom dance can contribute to a better control of blood pressure in medicated hypertensive patients, which may be considered as a cardiac rehabilitation exercise.

  17. Measurement of $Br(D^{0}\\to K^{-}\\pi^{+})$ using Partial Reconstruction of $\\overline{B}\\to D^{*+}X l^{-}\\overline{\

    CERN Document Server

    Artuso, M; Efimov, A; Goldberg, M; He, D; Kopp, S E; Moneti, G C; Mountain, R; Schuh, S; Skwarnicki, T; Stone, S; Viehhauser, G; Xing, X; Bartelt, J; Csorna, S E; Jain, V; McLean, K W; Marka, S; Godang, R; Kinoshita, K; Lai, I C; Pomianowski, P A; Schrenk, S; Bonvicini, G; Cinabro, D; Greene, R; Perera, L P; Zhou, G J; Chadha, M; Chan, S; Eigen, G; Miller, J S; O'Grady, C; Schmidtler, M; Urheim, J; Weinstein, A J; Würthwein, F; Bliss, D W; Masek, G E; Paar, H P; Prell, S; Sharma, V; Asner, D M; Gronberg, J B; Hill, T S; Lange, D J; Morrison, R J; Nelson, H N; Nelson, T K; Roberts, D; Ryd, A; Balest, R; Behrens, B H; Ford, W T; Park, H; Roy, J D; Smith, J G; Alexander, J P; Baker, R; Bebek, C; Berger, B E; Berkelman, K; Bloom, K; Boisvert, V; Cassel, David G; Crowcroft, D S; Dickson, M; Von Dombrowski, S; Drell, P S; Ecklund, K M; Ehrlich, R; Foland, A D; Gaidarev, P B; Gibbons, L K; Gittelman, B; Gray, S W; Hartill, D L; Heltsley, B K; Hopman, P I; Kandaswamy, J; Kim, P C; Kreinick, D L; Lee, T; Liu, Y; Mistry, N B; Ng, C R; Nordberg, E; Ogg, M; Patterson, J R; Peterson, D; Riley, D; Soffer, A; Valant-Spaight, B L; Ward, C; Athanas, M; Avery, P; Jones, C D; Lohner, M; Patton, S; Prescott, C; Yelton, J; Zheng, J; Brandenburg, G; Briere, R A; Ershov, A; Gao, Y S; Kim, D Y J; Wilson, R; Yamamoto, H; Browder, T E; Li, Y; Rodríguez, J L; Bergfeld, T; Eisenstein, B I; Ernst, J; Gladding, G E; Gollin, G D; Hans, R M; Johnson, E; Karliner, I; Marsh, M A; Palmer, M; Selen, M; Thaler, J J; Edwards, K W; Bellerive, A; Janicek, R; MacFarlane, D B; Patel, P M; Sadoff, A J; Ammar, R; Baringer, P; Bean, A; Besson, D; Coppage, D; Darling, C L; Davis, R; Kotov, S A; Kravchenko, I V; Kwak, N; Zhou, L; Anderson, S; Kubota, Y; Lee, S J; O'Neill, J J; Poling, R A; Riehle, T; Smith, A; Alam, M S; Athar, S B; Ling, Z; Mahmood, A H; Timm, S; Wappler, F; Anastassov, A; Duboscq, J E; Fujino, D; Gan, K K; Hart, T; Honscheid, K; Kagan, H; Kass, R; Lee, J; Spencer, M B; Sung, M; Undrus, A E; Wanke, R; Wolf, A; Zoeller, M M; Nemati, B; Richichi, S J; Ross, W R; Severini, H; Skubic, P L; Bishai, M; Fast, J; Hinson, J W; Menon, N; Miller, D H; Shibata, E I; Shipsey, I P J; Yurko, M; Glenn, S; Johnson, S D; Kwon, Y; Roberts, S; Thorndike, E H; Jessop, C P; Lingel, K; Marsiske, H; Perl, Martin Lewis; Savinov, V; Ugolini, D W; Wang, R; Zhou, X; Coan, T E; Fadeev, V; Korolkov, I Ya; Maravin, Y; Narsky, I; Shelkov, V; Staeck, J; Stroynowski, R; Volobuev, I P; Ye, J

    1998-01-01

    We present a measurement of the absolute branching fraction for $D^0 -> K^- pi^+$ using the reconstruction of the decay chain $Bbar -> D^{*+} X l^- nubar $, $D^{*+} -> D^0 pi^+$ where only the lepton and the low-momentum pion from the $D^{*+}$ are detected. With data collected by the CLEO II detector at the Cornell Electron Storage Ring, we have determined $Br(D^0 -> K^- pi^+)= [3.81 +- 0.15(stat.) +- 0.16(syst.)]%$.

  18. A literatura e a teologia http://dx.doi.org/10.15601/1983-7631/rt.v3n5p164-167

    Directory of Open Access Journals (Sweden)

    Genilma Boehler

    2011-04-01

    Full Text Available Trata-se de uma reflexão sobre literatura e teologia, pontualmente sobre poesia e teologia. Como afirmou Edgar Morin “a literatura tem a vantagem de refletir sobre a complexidade do ser humano e sobre a quantidade incrível de seus sonhos” (MORIN, 2009:6. Já a teologia, como definida por Rubem Alves, é “um jeito de falar sobre tais coisas dando-lhes um nome e apenas distinguindo-se da poesia porque a teologia é sempre feita como prece...” (ALVES, 2005:21. O encontro das duas é a ocasião para que seja feita uma reflexão acerca de Deus, a partir do espaço da poesia, recorrendo a outra linguagem, outro conhecimento, outras bibliotecas, considerando o corpo, o desejo, a vida, o mundo na medida em que apresenta a pessoa, a sociedade e a cultura.Palavras-chave: Teologia; Literatura

  19. THE CAPITAL STRUCTURE AS A RESOURCE AND THE EFFECT ON PERFORMANCE OF FIRMShttp://dx.doi.org/10.5585/riae.v9i1.1661

    Directory of Open Access Journals (Sweden)

    Silvio Parodi Camilo

    2010-07-01

    Full Text Available This article aims to expand the current theoretical and empirical understanding of the capital structure as an important resource to research a firm’s performance, from a financial and strategic perspective. Empirical research on resource-based-view (RBV has either focused on the effects of technological resources and innovative capacity or resources associated with operational efficiency. One feature deserving attention in turbulent environments, such as in Brazil, is the capital structure, as the combination of funding sources is a vital decision. Data was collected from Bovespa listed firms between 2002 and 2007. Two performance constructs were suggested and assessed; firm performance was measured through return on operational assets (ROA and return on equity (ROE. Results provide empirical evidence that decisions concerning financial leverage (DFL are relevant to enhance competitive advantage. This study was inconclusive regarding the capital structure’s influence on the ROA.

  20. Shoulder rotator isokinetic strength profile in young swimmers. DOI: http://dx.doi.org/10.5007/1980-0037.2012v14n5p545

    Directory of Open Access Journals (Sweden)

    Pablo Tomas-Carus

    2012-09-01

    Full Text Available Considering that some studies suggest that shoulder rotators muscle imbal­ances are related to joint pain and injury, and that there are no normative data for young swimmers, the aim of this study was: i to describe the muscle balance, fatigue and isokinetic strength profile of the shoulder rotators in young swimmers; ii to compare the results between swimmers and a group of young non-practitioners; iii to contribute to the acquisition of normative data of unilateral ratios of shoulder rotators. We evaluated the shoulder rotators concentric strength and unilateral ratios (ratio between torque of external and internal rotators of 60 swimmers (age: 14.55 ± 0.5 years old; body mass: 61.16 ± 7.08 kg and 60 non-practitioners (age: 14.62 ± 0.49 years old; body mass: 60.22 ± 10.01 kg. The evaluation was performed in the sitting position (90° abduction and elbow flexion at 60º.s-1 and 180º.s-1 angular speeds using an isokinetic dynamometer (Biodex System 3. The results of the fatigue ratios revealed no differences between the groups. Swimmers showed unilateral ratios of 73.39 ± 17.26% in the dominant limb (DL and 77.89 ± 15,23% in the non-dominant limb (NDL for assessments at 60º.s-1. At 180º.s-1, ratios were 74.77± 13.99% for DL and 70.11 ± 14.57% for NDL. Swimmers presented greater muscle imbalance, and differed from non-practitioners in the ability to produce power with the internal rotators, which was significantly higher in the former group.

  1. Acute cardiovascular responses in a virtual environment simulate by Nintendo Wii. http://dx.doi.org/10.5007/1980-0037.2013v15n1p60

    Directory of Open Access Journals (Sweden)

    Renato Aparecido de Souza

    2013-01-01

    Full Text Available It has recently been verified using the Nintendo Wii in the health context. The aim of this study was to analyze the acute cardiovascular responses monitored by the behavior of heart rate, systolic blood pressure, diastolic blood pressure and double product in an environment virtually simulated by Nintendo Wii. The sample was consisted of 18 health college students with mean age 22.07 ± 1.34 years. The variables were observed with use of delta analysis (post value – prior value after 25 basketball shoots in two experimental situations: (I seating and (II jumping vertically. The results suggest the physical activity in a virtual environment emulated by Nintendo Wii is able to change the acute cardiovascular responses, mainly when performed in association with vertical jumps. Thus, the results support the feasibility use of the Nintendo Wii in training programs and favor its indication more securely.

  2. GOVERNANCE AND STRATEGY IMPLEMENTATION IN LOCAL CLUSTERS TO IMPROVE THE PERFORMANCEhttp://dx.doi.org/10.5585/riae.v9i2.1672

    Directory of Open Access Journals (Sweden)

    Helen Fischer Günther

    2010-11-01

    Full Text Available Micro, small and medium enterprises (MSME are designed to operate in networks, cooperatively, in order to obtain benefits that would not occur through the alone action, and encourage the development of local productive arrangements (LPA. Emerge the need for synergy between the actors, operationalized by the mechanisms of integration, which must be managed for efficiency. These characteristics of cooperation and interaction impact the achievement of the objectives and strategies, and administrative functions and plans. Therein appear one of the challenges of present time: how to implement the strategies, plans, and how to make the strategy works? Governance emerges, then, as a medium to achieve the objectives and, so, talk about it in the LPA extends the focus on developing management methods to maintain the idiosyncrasies, to the same extent as they contribute to the effectiveness and improvement in performance.

  3. http://dx.doi.org/10.4314/ajtcam.v10i2.18 E-mail: hkshin@kiom.re.kr

    African Journals Online (AJOL)

    AJTCAM

    ethanol (5 mL/kg body weight) by oral gavage. ... was excised for macroscopic examination and biochemical analysis. ... using various agents increased oxidative stress and markedly increased .... GSTNB (between GSH and TNB), is produced concomitantly and is reduced by glutathione reductase to recycle the GSH,.

  4. Evaluation of the Integral ∫−1+1 Plm,n(x)Plm−2,n(x) dx

    NARCIS (Netherlands)

    Brakman, C.M.

    1987-01-01

    Integrals of the type indicated can be evaluated using the Fourier-series development of the Jacobi-polynomials. An alternative procedure is given yielding an analytical expression in terms of l, m and n.

  5. DOI: https://dx.doi.org/10.4314/rj.v2i1.4A Philosophy and the ...

    African Journals Online (AJOL)

    Corporate Edition

    intelligence, the nervous system and so on (Skinner 38). .... the different aspects of reality as phenomena, physics for example studies the nature, ..... and methodology of science including conditions of reliable observation, classification,.

  6. Performance of phalangeal quantitative ultrasound parameters in the evaluation of reduced bone mineral density assessed by DX in patients with 21 hydroxylase deficiency.

    Science.gov (United States)

    Gonçalves, Ezequiel M; Sewaybricker, Leticia E; Baptista, Fatima; Silva, Analiza M; Carvalho, Wellington R G; Santos, Allan O; de Mello, Maricilda P; Lemos-Marini, Sofia H V; Guerra, Gil

    2014-07-01

    The purpose of this study was to verify the performance of quantitative ultrasound (QUS) parameters of proximal phalanges in the evaluation of reduced bone mineral density (BMD) in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency (21 OHD). Seventy patients with 21 OHD (41 females and 29 males), aged between 6-27 y were assessed. The QUS measurements, amplitude-dependent speed of sound (AD-SoS), bone transmission time (BTT), and ultrasound bone profile index (UBPI) were obtained using the BMD Sonic device (IGEA, Carpi, Italy) on the last four proximal phalanges in the non-dominant hand. BMD was determined by dual energy X-ray (DXA) across the total body and lumbar spine (LS). Total body and LS BMD were positively correlated to UBPI, BTT and AD-SoS (correlation coefficients ranged from 0.59-0.72, p bone mass in patients with 21 OHD.

  7. Measurement of the Deuteron Spin Structure Function $g_{1}^{d(x)}$ for $1(GeV/c)^{2} < Q^{2} < 40 (GeV/c)^{2}$

    CERN Document Server

    Anthony, P L; Averett, T; Band, H R; Berisso, M C; Borel, H; Bosted, P E; Bultmann, S L; Buénerd, M; Chupp, T E; Churchwell, S; Court, G R; Crabb, D; Day, D; Decowski, P; De Pietro, P; Erbacher, R; Erickson, R; Feltham, A; Fonvieille, H; Frlez, E; Gearhart, R A; Ghazikhanian, V; Gómez, J; Griffioen, K A; Harris, C; Houlden, M A; Hughes, E W; Hyde-Wright, C E; Igo, G; Incerti, S; Jensen, J; Johnson, J R; King, P M; Kolomensky, Yu G; Kuhn, S E; Lindgren, R; Lombard-Nelsen, R M; Marroncle, J; McCarthy, J; McKee, P; Meyer, Werner T; Mitchell, G; Mitchell, J; Olson, M; Penttila, S; Peterson, G; Petratos, G G; Pitthan, R; Pocanic, D; Prepost, R; Prescott, C; Qin, L M; Raue, B A; Reyna, D; Rochester, L S; Rock, S E; Rondon-Aramayo, O A; Sabatie, F; Sick, I; Smith, T; Sorrell, L; Staley, F; Lorant, S St; Stuart, L M; Szalata, Z M; Terrien, Y; Tobias, A; Todor, L; Toole, T; Trentalange, S; Walz, D; Welsh, R C; Wesselmann, F R; Wright, T R; Young, C C; Zeier, M; Zhu, H; Zihlmann, B

    1999-01-01

    New measurements are reported on the deuteron spin structure function g_1^d. These results were obtained from deep inelastic scattering of 48.3 GeV electrons on polarized deuterons in the kinematic range 0.01 < x < 0.9 and 1 < Q^2 < 40 (GeV/c)^2. These are the first high dose electron scattering data obtained using lithium deuteride (6Li2H) as the target material. Extrapolations of the data were performed to obtain moments of g_1^d, including Gamma_1^d, and the net quark polarization Delta Sigma.

  8. DOI: https://dx.doi.org/10.4314/rj.v2i1.5A Intelligibility criticism of ...

    African Journals Online (AJOL)

    Corporate Edition

    every science is knowledge that people have of themselves and the world. .... it is the best common thing shared, but for the good use of reason; Kant, by recalling that ... understanding frees man from determination by fortuitous empirical ...

  9. Língua: pluralismos, dinamismos, poder e textualidade http://dx.doi.org/10.15601/1983-7631/rt.v1n0p142-146

    Directory of Open Access Journals (Sweden)

    Alemar Silva Araújo Rena

    2012-04-01

    Full Text Available Para melhor lidar com textos em geral, questões como o universo contextual, estilo, jogos de estranhamento, funções da linguagem, a língua como poder, fatores de textualidade, entre outras, precisam ser estudadas e consideradas na práxis. Procurarei discorrer, neste artigo, sobre tais questões sob um viés ligado à realidade jornalística, sem, no entanto, ignorar reflexões em outros campos discursivos.Palavras-chave: Pluralismos; dinamismo; poder

  10. http://dx.doi.org/10.4314/ajtcam.v10i2.18 E-mail: hkshin@kiom.re.kr

    African Journals Online (AJOL)

    AJTCAM

    injury and assessed antioxidant acitivity in damaged gastric tissue. ... the vehicle, and the absolute-ethanol group (EtOH group) received absolute ... used for detection of superoxide radicals generated by xanthine oxidase and hypoxanthine.

  11. EFFECTUAL REASONING AND CAUSAL REASONING IN CREATING NEW BUSINESSES: A CASE STUDY http://dx.doi.org/10.5585/riae.v10i2.1718

    Directory of Open Access Journals (Sweden)

    Juan Miguel Rosa González

    2011-10-01

    Full Text Available This article focuses on the process of new business creation, considering the effectuation approach, which explains the phenomenon of entrepreneurship in a different perspective than the traditional causal approach. Beginning with a description of the effectual approach assumptions, a case study about the subject is presented in order to explore the logic of the business creation process. The case discusses a Brazilian organization created in 1980 to produce materials and services in steel industry. Through structured interview with the entrepreneur who idealized the business, the main events in the early stages of the project are described. The results show the relationship between entrepreneur’s means available at the time of the enterprise creation and the new business design. In addition, the entrepreneur preferred a strategy of drawing instead of a decision one, and gave priority to strategic partnerships as a substitute of formal market research. All these aspects are covered by the effectual approach.

  12. Binding energy of the complex (D+-X) with Γ-X mixing in GaAs/AlAs quantum wells

    Science.gov (United States)

    Cunha Lima, I. C.; Ghazali, A.; Emmel, P. D.

    1996-11-01

    The binding energy of excitons to ionized shallow donors in a GaAs/AlAs quantum well in the vicinity of the type-I to type-II transition is obtained for impurities lying anywhere in the structure. We include the Γ-X hybridization in the Brillouin zone, which comes into play when the energies of the conduction subband minima in the two materials become closer. The calculation is performed variationally using a three parameters trial function similar to the one describing a singly ionized molecule. The same model allows the calculation of the binding energies of the neutral impurity and of the free exciton. We obtain that a ratio between the binding energy of the exciton to an ionized donor and that of the neutral donor equals 0.95+/-0.005, for all values of well widths explored, and independent of the impurity position inside the well. The joint density of states for the transition from free to bound exciton is obtained, and a discussion is presented on the role played by the doping and the compensation on the exciton dynamics.

  13. DOI: https://dx.doi.org/10.4314/rj.v2i1.3A Language of Religion and ...

    African Journals Online (AJOL)

    Corporate Edition

    a language to say the inhospitable: the terrible nature. ... the positive postulate, but which concurs with all religious and philosophical traditions: man is .... the victim, forgiveness is the meeting-place and the release of the fault, the shame and ...

  14. Beneficial Effects of Fractions of Nardostachys jatamansi on Lipopolysaccharide-Induced Inflammatory Response

    Directory of Open Access Journals (Sweden)

    Gi-Sang Bae

    2014-01-01

    Full Text Available It has been previously shown that Nardostachys jatamansi (NJ exhibits anti-inflammatory properties against lipopolysaccharide (LPS challenges. However, the potency of NJ constituents against LPS-induced inflammatory responses has not been examined. In this present study, we determined which NJ extract fractions exhibit inhibitory effects against LPS-induced inflammatory responses. Among the NJ fractions, NJ-1, NJ-3, NJ-4, and NJ-6 inhibited LPS-induced production of NO. The NJ-3, NJ-4, and NJ-6 fractions also inhibited the production of cytokines, such as IL-1β, IL-6, and TNF-α. However, NJ-1, NJ-3, NJ-4, and NJ-6 showed differential inhibitory mechanisms against LPS-induced inflammatory responses. NJ-1, NJ-3, and NJ-4 inhibited LPS-induced activation of c-jun NH2-terminal kinase (JNK and p38 but did not affect activation of extracellular signal-regulated kinase (ERK or NF-κB. On the other hand, NJ-6 inhibited activation of MAPKs and NF-κB. In addition, in vivo experiments revealed that administration of NJ-1, NJ-3, NJ-4, and NJ-6 reduced LPS-induced endotoxin shock, with NJ-6 especially showing a marked protective effect. Taken together, these results provide the evidence for the potential of selective NJ fractions against LPS-induced inflammation. Thus, it will be advantageous to further isolate and determine single effective compounds from these potent fractions.

  15. "Keeping it Real -High School Science Curriculum"- Hurricane Katrina and BP Oil Spill inspire creative curriculum by Dave Jungblut, Oakcrest High School Science Teacher, Mays Landing, NJ

    Science.gov (United States)

    Jungblut, D.

    2011-12-01

    After Hurricane Katrina devastated Gulf Coast homes in 2005, Oakcrest High School science teacher and geologist, Dave Jungblut, traveled from Gulfport to Ocean Springs, Mississippi and conducted research to determine whether property damage was caused by wind or water. Jungblut wrote several studies, " Katrina Straight- Line Wind Field Study", "Applying Research to Practical Use for Hurricane Katrina Homeowners", and "Hurricane Katrina Wind Study" proving wind damage. Jungblut's research, done pro bono, helped thousands of homeowner's in the Mississippi area be reimbursed by insurance companies for wind damage caused by Hurricane Katrina http://www.hurricanekatrinastudy.com/ Jungblut incorporated his extensive data, in a high school curriculum that is now part of the science program he teaches each year. In January 2010, Jungblut presented "Hurricane Forensics" curriculum at the Rutgers Center for Mathematics, Science and Computer January 2009 Workshop http://www.dimacs.rutgers.edu/wst/. Through labs and creative hands-on activities, Jungblut challenged his students to analyze the photographic evidence, and data he collected, for themselves. Jungblut taught his students how to use geologic and forensic inquiry techniques to discover the difference between straight-line winds from microburst activity. The students applied the concept of the Geological Principle of Relative Dating, to determine the sequence of events that happened during Hurricane Katrina. They built model structures, which were subjected to wind and water forces to better understand the effects of these phenomena, Finally, the students evaluated local and worldwide environmental issues, such as land use risks and benefits, in the face of global warming, In the spring of 2010 when the BP Oil Spill occurred, Jungblut realized, another opportunity to bring real world issues into the classroom. After exploring scientific concepts relating to this environmental crisis, Jungblut challenged his students to devise creative solutions to stop the leak. This project was profiled on June 4th, 2010 on the CBS National News with Katie Couric, "Kids Solution to the BP Oil Spill" http://www.cbsnews.com/video/watch/?id=6549408n&tag=contentMain;contentBody Jungblut continues seeking creative ways to inspire real solutions to real world problems in his classroom as the Japan's earthquake, tsunami and nuclear disaster became a group learning activities for his students.

  16. National Dam Safety Program. Lake Wanda Dam (NJ00510), Hudson River Basin, Tributary to Wawayanda Creek, Sussex County, New Jersey. Phase 1 Inspection Report.

    Science.gov (United States)

    1980-03-01

    Cheke SQUARES 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 1/4 IN. SCALE 1 3 4 4= 2. P7 1,, 5PilW/V 9 10 12 13...191, ~ C! . .. .. C.C C C L. C . C W .C . . . .C .C . . . .C .C . . . . .C . C . C C. . C . C 4 4 . . . a CC aa acca a aa aa C C...4-9 - ---- 4. 4. CY C..L Q Z i m )4 %C .m 0 n o.C..Q J r o )%.? %c l r4 - a C. C’ C~~ C) C- C. C. CC - --- 04--. N Nl N% NY N N N N P7 ")7 F )7,F .F C

  17. National Dam Safety Program. Lake Windsor Dam (NJ-00034), Hudson River Basin, Tributary Papakating Creek, Sussex County, New Jersey. Phase I Inspection Report.

    Science.gov (United States)

    1981-03-01

    Potential." Visual inspection of the downstream area shows that breach of the dam would cause little damage to downstream residences which are...Le Novo( ~OIP o. a p" ,,_ _,_ o= (T ]l,4oo7/-2 4; J r ./0 /000 , By~ DATE1’V2.3Z oe -No. Igo JO CKD A~ DATE ____________SHEETNOOF LANGAN ENGINEERING...JOB NO. 4AZY , CKD -" - DATE3,tl/& SHEET NOJ.. OF. 10~ NN r Q ~Zf) A)i~ JO N O. .. ey WA... DATE JOBL " - ""~ HE NO. oJ2. loo ’.4 ~ye 41P~4~’ S

  18. National Dam Safety Program. Lake Stockholm Dam (NJ 00302), Passaic River Basin, Small Branch, Passaic County, New Jersey. Phase I Inspection Report.

    Science.gov (United States)

    1979-03-01

    been classified as having “High Hazard Potential” on the basis that failure of the dam would cause excessive property damage to residences downstream...and could potentially cause more than a few deaths. Visual inspection of the downstream area shows that breach of the dam would cause little damage...L ~ .~ tI-, _______ DATE I~ 7 .73 Li. k~~~ L .1 a ’ u s-. JOB NO. ~J’ 7~ ~ p CKD ~~~~) DATE L-bz?~L SHEET NO. ‘ OF ID I- ‘Cz~- I— 0 0 CL

  19. Home Environment, Self-Concept and Urban Student Achievement: A Bibliography and Review of Research. NJ Urban Education Research Reports No. 5.

    Science.gov (United States)

    Shapiro, Carol; Bloom, Joel S.

    This review analyzes recent research on student personality, social and home environment, and the influence of these factors on academic achievement, particularly among minority and disadvantaged students. Several factors which purportedly affect student achievement and which are examined in the review include: (1) socioeconomic status and its…

  20. EPA Honors 2015 Energy Star Combined Heat and Power Winners / Facilities in Maine, N.J., Texas recognized for emission reductions

    Science.gov (United States)

    WASHINGTON - The U.S. Environmental Protection Agency (EPA) is recognizing three facilities with the Energy Star Combined Heat and Power (CHP) Award for superior performance of their CHP systems. High-efficiency CHP technology reduces emissions of c

  1. National Dam Safety Program. Alcyon Lake Dam (NJ 00427) Delaware River Basin, Chestnut Branch-Mantua Creek, Gloucester County, New Jersey. Phase 1 Inspection Report.

    Science.gov (United States)

    1981-05-01

    froma small concreto , platform which extends out from the- culvert fas Ci,). The qate is divided into two section, and is mounted on a steel frame...se(ver al concreto fILurneS that0 e xiend fromn the, nrmcurhli me andI drain baick into the, reiser vo ir . AlIl were o-r i qi n a Iv e% qu i pped( wi

  2. Violent Crime Against the Elderly: A New Jersey Perspective. Hearing before the Select Committee on Aging. House of Representatives, Ninety-Ninth Congress, First Session (Plainfield, NJ).

    Science.gov (United States)

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document contains testimony from a Congressional hearing held in New Jersey to examine violent crime against the elderly. Opening statements are presented from committee members Matthew J. Rinaldo, William J. Hughes, Christopher H. Smith, and Dan Mica. Four panels of witnesses testify: (1) two elderly victims of violent crime; (2) federal,…

  3. Summary of the International Workshop on Magnetic Fusion Energy (MFE) Roadmapping in the ITER Era; 7-10 September 2011, Princeton, NJ, USA

    Science.gov (United States)

    Neilson, G. H.; Federici, G.; Li, J.; Maisonnier, D.; Wolf, R.

    2012-04-01

    With the ITER project now well under way, the countries engaged in fusion research are planning, with renewed intensity, the research and major facilities needed to develop the science and technology for harnessing fusion energy. The Workshop on MFE Roadmapping in the ITER Era was organized to provide a timely forum for an international exchange of technical information and strategic perspectives on how best to tackle the remaining challenges leading to a magnetic fusion DEMO, a nuclear fusion device or devices with a level of physics and technology integration necessary to cover the essential elements of a commercial fusion power plant. Presentations addressed issues under four topics: (1) Perspectives on DEMO and the roadmap to DEMO; (2) Technology; (3) Physics-Technology integration and optimization; and (4) Major facilities on the path to DEMO. Participants identified a set of technical issues of high strategic importance, where the development strategy strongly influences the overall roadmap, and where there are divergent understandings in the world community, namely (1) the assumptions used in fusion design codes, (2) the strategy for fusion materials development, (3) the strategy for blanket development, (4) the strategy for plasma exhaust solution development and (5) the requirements and state of readiness for next-step facility options. It was concluded that there is a need to continue and to focus the international discussion concerning the scientific and technical issues that determine the fusion roadmap, and it was suggested that an international activity be organized under appropriate auspices to foster international cooperation on these issues.

  4. Treatment refusal/attrition among adults randomly assigned to programs at a drug treatment campus: The New Jersey Substance Abuse Treatment Campus, Seacaucus, NJ.

    Science.gov (United States)

    Condelli, W S; Koch, M A; Fletcher, B

    2000-06-01

    The New Jersey Substance Abuse Treatment Campus was funded to assess the feasibility of establishing a new model for delivering substance abuse treatment services and to serve as a research laboratory for conducting comparative evaluations of those services. The 350-bed campus was designed to improve treatment effectiveness by providing special services needed by underserved populations, and reduce treatment costs by serving large numbers of clients, centralizing services, and sharing facilities. First-time clients who met preliminary eligibility requirements during phone screening were randomly assigned to therapeutic community and chemical dependency programs. We used data collected on 1,573 adults who were ultimately accepted for admission to analyze treatment refusals and attrition during the 25 days after admission. Only 6.4% of the clients refused admission when informed of their treatment assignment. Planned duration of the residential phase of treatment, gender, and language spoken (English/Spanish) interacted with one another and differentially predicted treatment refusal/attrition. These findings may be useful for understanding treatment refusal and attrition in substance abuse treatment programs.

  5. National Dam Safety Program. Lake Intervale Dam (NJ00769), Passaic River Basin, Troy Brook, Morris County, New Jersey. Phase I Inspection Report.

    Science.gov (United States)

    1981-05-01

    L 414{ STORCH ENGINEERS sheef .. L of 1L. Project t Made By Dae______ ____ ~Chkd By .Jc; Date /7 / = - ~ _&-+hod_ P4__ _ _ _ _7 __,;; 4 L_ _ _1 2...STORCH ENGINEERS Sheef -9 of 43 Project /A7 ER VAW LEAk’E Moally I/A Date 2-2C-At ________________________________Chkd Byr uc; Date Al/K.e/er. 3l7

  6. https://drive.google.com/file/d/0B8lgDBwl33UqNjRhSmgwc3owZmM/view

    Directory of Open Access Journals (Sweden)

    Abol Hassanafkar,

    2016-11-01

    Full Text Available Background:.The stewardship and social responsibility of the Ministry of Health insist on developing frameworks that improved clinical outcomes and lifequality. Objective:This study aimed to evaluate National Evidence Based Health Care System (NEBHCS in Iran. Methods:This review study was surveyed achievements of National Evidence Based Health Care Systemimplementation in Iran by reviewing and studying books, articles and Comparing official documents and Hospital Evaluation Standards in the field of Evidence Based Medicine, Findings:Four types of Clinical Practice Guideline havedeveloped by the Ministry ofHealth during last decade. Evidence Based Medicine Standards in Hospital Evaluation Standards have been developed since 2010. The Standardization of Clinical Practice GuidelineDepartment in the Ministry ofHealth was developed NEBHCS includes model, structure, processes and policies in support of National Clinical Practice Guidelines. Educational and Research Agreements signed between Deputies of the Ministry ofHealth to facilitate the implementation process. Conclusion: According to the results, more attention of medical academic communities and national policy makers is essential in implementation of program.

  7. MODFLOW-2005 and MT3DMS models used to design and evaluate a bioremediation experiment at the former Naval Air Warfare Center, West Trenton, NJ

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — MODFLOW-2005 groundwater flow models and MT3DMS solute transport models were developed to represent conditions in the vicinity of a bioremediation experiment...

  8. National Dam Safety Program. Lake Ashroe Dam (NJ00023), Delaware River Basin, Branch of Big Flat Brook, Sussex County, New Jersey. Phase I Inspection Report.

    Science.gov (United States)

    1981-03-01

    discharges into the spillway riser. A toe drain ) system which involved 4-inch diameter perforated asbestos-cement pipes and a rock fill toe blanket...repaired by the placement of cobbles and boulders. There appeared to be no warning system in effect. SECTION 5 HYDRAULIC/HYDROLOGIC Available...r* T oLAVE ASI-4FOE 4’,4 625- 1 5LRlCC PO H’ cI.AES i AS AD0’ IPTV ~ S~IA AWVIN SCOUT LIESERVATION AT LAI-E Asl4jzoe ("s7--12z) P-~ATe:P MAY, 1969

  9. National Dam Safety Program. Lake Ames Dam (NJ00337), Passaic River Basin, Hibernia Brook, Morris County, New Jersey. Phase I Inspection Report.

    Science.gov (United States)

    1980-02-01

    r - . V . dvi - .0. P.-w0 04P - 1 t in N %DI L I C; C;**- 9 I;C z C;1 ; 1 C& w Fl W.P.wF -IY-o Y rL rh rk * 6n o-p!W q1)W )W -- ~~~P - .-- ; r- C...Bureau, "Seasonal Variation of the Probable Maximum Precipitation East of the 105th Meridian for Areas from 10 to 1000 Square Miles and Durations of 6

  10. NOAA Office for Coastal Management Benthic Habitat Data, Long Island Sound, Jamaica Bay, and Lower Bay of NY/NJ Harbor, NY, 1994-2002 (NODC Accession 0089467)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data are a collection of benthic habitat data from studies conducted in the coastal Long Island Sound, NY region in GIS shapefile (.shp, .dbf, .shx, and .prj...

  11. National Dam Safety Program. Rock Ridge Lake Dam (NJ 00178), Passaic River Basin, Rockaway River, Morris County, New Jersey. Phase 1 Inspection Report

    Science.gov (United States)

    1979-08-01

    DFT10% OF INOV 65IS OBSOLEE :1f Ij Is- DEPARTMENT OF THE ARMY PHILADLLPHIA DISTRICT. CORPS OF ENGINEERS CUSTOM HOUSE-2 D & CHESTNUT STREETS PHILADELPHIA...Pal’ Downstream slope 221 9Foundation material Uskaow Mtax height 8.5tfe Vyp of %piliwe Concrete broad-oreted voir. C a/ Lewgh of Spillway 40’ feet X.3

  12. National Dam Safety Program. Lake Valentine Dam (NJ00297) Delaware River Basin, Branch of the Pequest River, Sussex County, New Jersey. Phase 1 Inspection Report.

    Science.gov (United States)

    1980-01-01

    B WOODEN STOPLOG (4’xlx2) HOUSE a15 Via T CHANNEL SECTION APPROX. 900’ DOWNSTREAM OF DAM SEEPAGELAKE VALENTINE 15 WOODEN FOOTBRIDGE r(4’xl’xe... FOOTBRIDGE (Wooden Deck) ]HOUSE HOUSE PLAN cufl DATA FROM FIELD INSPECTION 11/9/79 Anderson- Nichols 5 Ca, Inc [U.S. ARMY ENGINEER DIST PHIL ADELPH4IA CORPS

  13. National Dam Safety Program. Seneca Lake Dam (NJ00768), Delaware River Basin, Lubbers Run, Sussex County, New Jersey. Phase 1 Inspection Report.

    Science.gov (United States)

    1981-06-01

    CFIGURET2 CONCRET- B MASONRY SlOE WALL TIMBER a PLANK FOOTBRIDGE E L. 85 6,5 EL. 855 I7 I EL 854 25 9FLASHBOARD--/ I - 30 12" CONCRETE APRON NATURAL...February,1981 View of Seepage and Outlet Channel February 1981 View of Spillway and Footbridge February 1981 View of Downstream Road Bridge diI CHECk LIST

  14. Microbial effects on sorption and transport of actinides in tuff samples from the Nevada Test Site and soils from McGuire AFB, NJ

    Science.gov (United States)

    Fisher, J. C.; Gostic, R.; Gostic, J.; Czerwinski, K.; Moser, D. P.

    2009-12-01

    The sorption and behavior of various actinides were examined for two sets of environmental samples. The Nevada Test Site (NTS) harbors a variety of radionuclides resulting from atomic weapons testing from the 1950s-1990s. Modeling the transport of radionuclides at the NTS is difficult because each detonation cavity is a unique environment with distinct hydrologic characteristics, chemical composition, and microbial community structure. McGuire AFB was the site of an explosion that resulted in the burning of a BOMARC nuclear missile and deposition of particles containing high-fired oxides of Am, Pu, and U in soils on the base. Analysis of the NTS samples focused on sorption/desorption of 233-U and 241-Am in the presence/absence of bacteria, and work on the BOMARC cores addressed the potential role of microorganisms in mediating particle degradation and movement. Batch experiments with various NTS tuff samples and strains of bacteria showed that sorption of actinides may be enhanced by >25% under certain conditions by bacteria. Sorption of 233-U was highly dependent on carbonate concentrations in the liquid matrix, while 241-Am was unaffected. Different bacterial species also affected sorption differently. Sorption kinetics for both actinides were rapid, with maximum sorption usually occurring within 4 hours. Actinides bound tightly to tuff and little desorption occurred in carbonate-free batch experiments. Column experiments showed that bacterial cultures in minimal salts buffer desorbed significantly more 233-U from tuff than low carbonate NTS water, but less than 30 mM bicarbonate buffer. Hot particles in the BOMARC cores were located using CT mapping and were extracted from the soil prior to analysis of core sections by gamma spectroscopy. Subcores for DNA extraction and culturing were collected from soil in direct contact with hot particles. The extracted particles consisted of a mixture of weapons-grade Pu, 241-Am and 235-U and ranged in activity from 5-66 kBq 241-Am. 241-Am distribution within the cores did not follow an expected pattern. While 241-Am concentrations typically tapered off with distance from the hot particle, there were several discrete spikes in Am-241. These characteristics are indicative of surface area-driven processes such as sorption and desorption of material to the soil from the particle. Culturing of bacteria directly from the hot particles and DNA extraction/T-RFLP analysis revealed diverse microbial communities. These organisms may directly or indirectly contribute to the dissolution of the hot particle via production of organic ligands (e.g. citrate) or redox reactions. The results of the tuff study support the hypothesis that the bacteria may facilitate transport of the Am-241 and may help explain its unexpected distribution in the cores. These experiments highlight the potential importance of bacteria in the transport of actinides in highly dissimilar environments.

  15. National Dam Safety Program. J. Seward Johnson Dam (NJ00770). Raritan River Basin, Cold Brook, Hunterdon County, New Jersey. Phase I. Inspection Report.

    Science.gov (United States)

    1981-03-01

    i - -i -~ - - 0 - - - - - -n -n -n -n - w 0 0 L0 ~~ 0000 0000000 000000000Ooooooooooo 000000z m------- - ------ nini i i r r qr-z-----n rioty m...a- nini -- l r- 0 .4 w I ) ,0nr ) ,4 nrr ra o r n- n 0 1 , qC dC .]C n n mc )r - . t- 7 BY -- DATE LOUIS BERGER & ASSOCIATES INC. SHEET NO CHKO. BY

  16. EPA Finalizes Plan to Address Contaminated Groundwater at Curtis Specialty Papers Superfund Site in Milford Borough and Alexandria Township, N.J.

    Science.gov (United States)

    (New York, N.Y.) The U.S. Environmental Protection Agency has finalized a plan to clean up contaminated groundwater at the Curtis Specialty Papers Superfund site in Milford Borough and Alexandria Township, New Jersey. The site includes the former Milford P

  17. General Aviation Aircraft Safety, The Princeton University Conference (119th) Held at Princeton, N.J. on October 24-25 1973

    Science.gov (United States)

    1974-10-01

    Accident Records" 3 Charles 0. Miller, Director, Bureau of Aviation Safety, National Transportation Safety Board "General Aviation Accident Patterns...Accident Records Charles 0. Miller Director, Bureau of Aviation Safety National Transportation Safety Board The title of my paper today, "An Analysis...Bethesda, Maryland 20014 Aviation Consumer Magazine James Holahan Pan Am Bldg., Teterboro Airport Bally Tully Teterboro New Jersey 07608 Bede Aircraft

  18. NOAA Digital Oblique Imagery Collection for the Coasts of Main/New Hampshire, Massachusetts/Rhode Island/Connecticut, and Hudson River/Long Island /NY/NJ

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Project: NOAA Digital Orthophotography and Ancillary Oblique Imagery Collection for the Coasts of Main/New Hampshire, Massachusetts/Rhode Island/Connecticut, and...

  19. Ingesta dietética de hierro y su deficiencia en las jugadoras de voleibol femenino de élite Dietary iron intake and deficiency in elite women volleyball players

    Directory of Open Access Journals (Sweden)

    J. Mielgo-Ayuso

    2012-10-01

    Full Text Available Introducción: La práctica del voleibol requiere repetidos impactos en brazos y pies provocados por saltos verticales, caídas, remates, cambios bruscos y rápidos de dirección, por lo que se nos podría plantear problemas en el metabolismo del hierro (Fe y la ingesta recomendada de Fe de 18 mg/día (en el colectivo femenino a nivel general, no sea suficiente para cubrir las necesidades de Fe de las jugadoras de voleibol femenino (JVF. Objetivo: Evaluar el estado de los depósitos de Fe mediante los cambios producidos en la ferritina sérica (FS e índice de saturación de transferrina (IST y evaluar la ingesta de Fe tras 11 semanas de entrenamiento. Métodos: Se analizó la FS e IST de 10 JVF de un equipo de la Superliga española (26,6 ± 5,9 años y talla 178,05 ± 8,7 cm en dos momentos de la temporada: Semana 0 (previo al inicio de los entrenamientos de pretemporada y semana 11 (tras 11 semanas de entrenamiento y 6 partidos de la liga regular. Así mismo se calculó el consumo de Fe en este periodo a partir de cuestionarios de frecuencia de consumo de alimentos elaborados y comprobados a partir de registros dietéticos de 7 días. Resultados: Se observó que una ingesta de 25,8 mg/día de Fe dietario no es suficiente para prevenir que un 30% de las JVF sufran déficit de Fe pre-latente y el 20% déficit latente (pre-anemia. Conclusión: Sería recomendable la realización de analíticas periódicas y una educación alimentaria, enseñando que alimentos contienen un alto contenido en Fe de tipo hemo, así como los factores que pueden interferir en su absorción.Introduction: Volleyball practice requires repeated impacts on arms and feet caused by vertical jumps, falls, auctions, sudden and rapid changes of direction, which is why might raise us problems in the metabolism of iron (Fe and the recommended intake of 18 mg/day (in the women in general, is not sufficient to meet the needs of the players of volleyball female (JVF. Objective: We

  20. 75 FR 35089 - Notice Pursuant to the National Cooperative Research and Production Act of 1993; National...

    Science.gov (United States)

    2010-06-21

    ..., Santa Fe, NM; AMEC, Somerset, NJ; Applied Research Associates, Albuquerque, NM; Applied Spectra, Inc... Hopatcong, NJ; DCS Corporation, Alexandria, VA; Dynamic Systems and Research Corporation, Albuquerque,...

  1. Program “VAMOS” (Active Living, Enhancing Health: from conception to initial findings DOI: http://dx.doi.org/10.5007/1980-0037.2012v14n6p723

    Directory of Open Access Journals (Sweden)

    Luiz Salomão Ribas Gomez

    2012-11-01

    Full Text Available Despite increased governmental efforts towards promoting healthy and active lifestylesamong Brazilians, physical inactivity is a serious concern in the population. Therefore, wedeveloped a new approach to community interventions for the promotion of physical activitycalled “Project VAMOS: Active Living, Enhancing Health”. In this article we review information about the conception of the program, as well as name, brand, and logo development. We discussissues related to translation and cultural adaptation, evaluation strategies, and we review lessonslearned from the pilot phase of the project that involved older adults and public health centers(CS in Florianopolis. One hundred older adults registered in six CS participated in the pilot study.They were randomly assigned into three different groups: “VAMOS” (n=33, traditional physicalactivity classes (n=35, and a control group (n=32. “VAMOS” is an educational program basedon behavioral change principles that consists of 12 meetings. Based on an American evidence--based program (“Active Living Every Day”, “VAMOS” was translated and culturally adaptedto the Brazilian context. A number of adjustments were made to the original American versionof the program prior to conducting the pilot study. For example, the content of the lessons andhomework were revised, we shortened the length of the lessons, as well as lowered the complexityof some of the materials. The results of the pilot study suggest that there was broad acceptanceof the “VAMOS“program by the older adult participants. Also, interviews with administrativestaff and health professionals working for the CS indicated a possibility and interest to continueto offer “VAMOS” as part of their regular programming for the community. In summary, “VAMOS”has great potential to be used with the Brazilian population. Adjustments are necessaryfor its utilization with other age groups and across different regions in Brazil.

  2. Fatores associados à baixa adesão ao aleitamento materno exclusivo e ao desmame precoce http://dx.doi.org/10.15601/1983-7631/rt.v6n11p154-16

    Directory of Open Access Journals (Sweden)

    Jaqueline Almeida Guimarães Barbosa

    2013-11-01

    Full Text Available Resumo: O leite materno é um alimento completo e o mais adequado para bebês, sendo recomendado seu uso exclusivo até os seis meses de vida. Contudo, ainda é insatisfatória a adesão a tal prática. O objetivo deste estudo foi identificar os fatores associados a não adesão ao aleitamento materno exclusivo e ao desmame precoce, visando contribuir com conhecimentos que auxiliem a reverter esse cenário. Trata-se de revisão de literatura. Identificou que, além de haver desconhecimento acerca dos benefícios do aleitamento materno, mitos e crenças infundadas contribuem para dificultar a adesão a tal prática. Além disso, a amamentação sofre influências do contexto, como da disponibilidade da mãe, e do acesso a recursos como o leite em pó e mamadeiras. Faz-se necessário oferecer orientações qualificadas com abordagens que considerem os aspectos psicossociais envolvidos no comportamento das mães, a fim de que alcancem maior eficácia.Palavras-chave: amamentação, desmame precoce, enfermagem Abstract: Maternal milk is a complete food and the most adjusted for babies, being recommended its exclusive use until the six months of life. However, still the adhesion to such practical is unsatisfactory. The objective of this study was to identify to the factors associates of the little adhesion to the exclusive breast feed and to it weans it precocious, aiming at to contribute with knowledge that assist to revert this scene. One is about literature revision. It identified that, beyond having unfamiliarity concerning the benefits of the breast feed, myths and baseless beliefs they contribute to make it difficult the adhesion to such practical. Moreover, breast-feeding suffers influences from the context, as of the availability of the mother, and the access the resources as milk in dust and baby's bottles. One becomes necessary to offer qualified orientation that consider the involved social-cultural aspects in the behavior of the mothers, so that they reach greater effectiveness.Key words: breast-feeding, weans precocious, nursing

  3. Analysis of group cohesion levels and pre-competitive psychological stress in volleyball athletes.. http://dx.doi.org/10.5007/1980-0037.2012v14n6p704

    Directory of Open Access Journals (Sweden)

    Guilherme Moraes Balbim

    2012-11-01

    Full Text Available This descriptive study was designed to analyze the level of group cohesion and pre-competitive psychological stress of adult volleyball athletes. The subjects consisted of 155 male and female athletes from the state of Parana who played in the JAPS/ 1st division (A, and 2nd division (B. The assessment instruments used were the Group Environment Questionnaire (GEQ and the Volleyball Psychic Stress Test (V-PST. For data analysis, the following tools were used: Cronbach’s alpha, Kolmogorov-Smirnov, Mann-Whitney, one-way Anova, and Tukey’s post hoc (p<0.05. The results revealed that athletes of division A were more negatively influenced by stress factors than the athletes of division B; in terms of individual attraction to the social group (p=0.014 and tasks (p=0016 athletes of division B had higher levels of group cohesion than athletes from division A; athletes with low social cohesion were negatively impacted by factors of "inappropriate physical conditioning" and "excessive nervousness;" athletes with low levels of cohesion for the task were negatively influenced by the factors of "Pressure from other people to win" and positively by the factor "Behavior of the fans in the game outside." It was concluded that group cohesion is demonstrated to be an intervening factor in pre-competitive stress thereby demonstrating that the higher the dispute level, the higher the negative influence of stress.

  4. Síndrome de Asperger: relato de um caso http://dx.doi.org/10.15601/1983-7631/rt.v1n1p90-97

    Directory of Open Access Journals (Sweden)

    Letícia Viana Pereira

    2012-04-01

    Full Text Available Objetivo: O presente estudo tem como real objetivo o relato de um caso de Síndrome de Asperger comprado às características descritas na literatura. Metodologia: A partir de um relato de um caso atendido na Clínica Escola de Fonoaudiologia do Centro Universitário Metodista Izabela Hendrix, determinadas características foram comparadas com o descrito na literatura pertinente. Os trabalhos foram lidos, fichados e agrupados, segundos algumas características de abordagem, para posterior análise e comparação com o caso clínico relatado. Discussão e resultados: As crianças com Síndrome de Asperger são, em geral, diferentes entre si. Freqüentemente procedimentos realizados que podem ser indicados para uma criança seriam inadequados para outra. Assim, sugestões apresentadas pela literatura devem ser consideradas para melhorar a assistência à criança, como a compreensão mais abrangente e a reflexão aprofundada em relação a cada caso em específico. Conclusão: O acompanhamento e tratamento fonoaudiológico nesses casos, é de suma importância para o desenvolvimento o mais próximo possível do considerado formal na linguagem e na comunicação destes indivíduos. Vivências clínicas mostram as estratégias que podem ser sugeridas para estas crianças, lembrando que casa criança possui suas particularidades, que devem sempre ser levadas em consideração.Palavras-chave: Síndrome de Asperger; relato de caso; procedimentos terapêuticos

  5. A humanização do ser humano em Paulo Freire: a busca do “ser mais” DOI: http://dx.doi.org/10.15601/2237-0587/fd.v3n1p15-30

    Directory of Open Access Journals (Sweden)

    Ebenezer da Silva Melo Júnior

    2012-05-01

    Full Text Available A compreensão de Paulo Freire sobre a Humanização do Ser Humano constrói-se como ontologia do ser. Ele entende que o ser humano é um ser inacabado em processo constante de humanização. Para Freire Educação Libertadora é igual à humanização do ser humano.  Neste sentido, busca-se apresentar como o conceito de humanização em Paulo Freire é base de seu projeto para uma Educação Libertadora. Demonstra-se como Freire reconheceu a oposição histórica entre Humanização e Desumanização dos seres humanos bem como o caminho que ele indicou para a construção de uma Educação Libertadora, isto é, a passagem de uma consciência ingênua a uma consciência crítica capaz de tornar os educandos sujeitos do processo educativo bem como de sua própria história. 

  6. 给DSLR一个更广阔的视野 尼柯尔AF-S DX12-24mm f/4G 1F-ED镜头

    Institute of Scientific and Technical Information of China (English)

    张大鹏

    2004-01-01

    随着世界照相机工业的发展,数字单反相机(缩称DSLR)已经开始逐渐走入摄影师的生活,但是由于种种原因的限制,好多数字单反相机都不能做成35mm全片幅的图像感应器,这也就意味着以前在传统相机上使用的镜头现在用在数字单反相机上,

  7. Measurement of the Deuteron Spin Structure Function g{sub 1}{sup d}(x) for 1 (GeV/c){sup 2} < Q{sup 2} < 40 (GeV/c){sup 2}

    Energy Technology Data Exchange (ETDEWEB)

    Perry Anthony; R.G. Arnold; Todd Averett; H.R. Band; M.C. Berisso; H. Borel; Peter Bosted; Stephen Bueltmann; M. Buenerd; T. Chupp; Steve Churchwell; G.R. Court; Donald Crabb; Donal Day; Piotr Decowski; P. DePietro; R. Erbacher; R. Erickson; Andrew Feltham; Helene Fonvieille; Emil Frlez; R. Gearhart; V. Ghazikhanian; Javier Gomez; Keith Griffioen; C. Harris; M.A. Houlden; E.W. Hughes; Charles Hyde-Wright; G. Igo; Sebastien Incerti; John Jensen; J.R. Johnson; Paul King; Yu.G. Kolomensky; Sebastian Kuhn; Richard Lindgren; R.M. Lombard-Nelsen; Jacques Marroncle; James Mccarthy; Paul McKee; W. Meyer; G.S. Mitchell; Joseph Mitchell; Michael Olson; S. Penttila; Gerald Peterson; Gerassimos Petratos; R. Pitthan; Dinko Pocanic; R. Prepost; C. Prescott; Liming Qin; Brian Raue; D. Reyna; L.S. Rochester; Stephen Rock; Oscar Rondon-Aramayo; Franck Sabatie; Ingo Sick; T. Smith; L. Sorrell; F. Staley; S. St. Lorant; L.M. Stuart; Z. Szalata; Y. Terrien; William Tobias; Luminita Todor; T. Toole; S. Trentalange; Dieter Walz; Robert Welsh; Frank Wesselmann; T.R. Wright; C.C. Young; Markus Zeier; Hong Guo Zhu; Benedikt Zihlmann

    1999-09-30

    New measurements are reported on the deuteron spin structure function g{sub 1}{sup d}. These results were obtained from deep inelastic scattering of 48.3 GeV electrons on polarized deuterons in the kinematic range 0.01 < x < 0.9 and 1 < Q{sup 2} < 40 (GeV/c){sup 2}. These are the first high dose electron scattering data obtained using lithium deuteride ({sup 6}Li{sup 2}H) as the target material. Extrapolations of the data were performed to obtain moments of g{sub 1}{sup d}, including {Gamma}{sub 1}{sup d}, and the net quark polarization {Delta} {Sigma}.

  8. Expressões teóricas dos processos de libertação: novos paradigmas http://dx.doi.org/10.15601/1983-7631/rt.v6n11p213-228

    Directory of Open Access Journals (Sweden)

    Manuel Alfonso Díaz Muñoz

    2013-11-01

    Full Text Available O objeto deste artigo é descrever os eixos comuns às três expressões teóricas dos processos de libertação e apontar os novos paradigmas propostos perante os desafios que a contemporaneidade apresenta com a ajuda dos autores mais representativos de cada área: na teologia, Gustavo Gutiérrez; na filosofia, Enrique Dussel; na pedagogia, Paulo Freire. A análise dos novos paradigmas é feita a partir de James Cone (raça e cultura, Wanda Deifelt (gênero, Leonardo Boff (ecologia, Hans Küng (diálogo e paz e Sturla Stalsett (globalização. O resultado é um artigo que pretende fundamentar os pressupostos de uma reflexão teológica/pedagógica libertadora contemporânea.

  9. Assessment of physical growth through body proportionality in Peruvian children living at moderately elevated altitudes. http://dx.doi.org/10.5007/1980-0037.2012v14n6p690

    Directory of Open Access Journals (Sweden)

    Maria Fargueta

    2012-11-01

    Full Text Available The strategy of our approach involves the use of an instrument for measuring body proportionality for the purpose of comparing growth of segments to body dimensions. The objective of this descriptive transversal study is to assess physical growth through body proportionality of school children, aged 6 to 12 years, living at moderately elevated altitudes. Study participants included 482 females and 473 males ranging in ages from 6 to 12 years and possessing middle socioeconomic status. The students were selected from a stratified probability segment of 6,659 students. In all, we evaluated: anthropometric measurements of weight (kg, height (m, five skinfolds (mm, four body perimeters and four body-bone diameters. Proportionality analyses were performed using the Phantom theoretical model proposed by Ross and Wilson (1974. The results of the Phantom Z-scores for both genders show generally negative values for body weight (-3.7 to -1.7, skinfold thickness (0.5 to -1.5, and body circumference (-0.9 to -1.3. In turn, bone diameters show positive values in all ages as well as in both genders (1.0 to 3.2. The results suggest that school children living at moderately elevated altitudes are characterized by slow growth correlated to body weight; on the other hand, skinfold thicknesses and body circumferences in relation to bone diameters exhibit a tendency to robustness.

  10. Interação na diversidade: relato de aprendizagem cooperativa DOI: http://dx.doi.org/10.15601/2237-0587/fd.v8n1p71-81

    Directory of Open Access Journals (Sweden)

    Sandra Andrade de Castro

    2016-05-01

    Full Text Available O presente trabalho apresenta um relato de experiência inclusiva: interação entre duas turmas de escolas: comum – Colégio Metodista Izabela Hendrix e especial – Instituto São Rafael. A importância de tal relato aponta no sentido de fomentar aos educadores o processo de transformação da educação, considerando a diversidade. Para a reflexão da experiência, utilizou-se a legislação vigente sobre a inclusão, conceituação de aprendizagem de Vygotsky e aprendizagem cooperativa do Ministério da Educação. A experiência ocorreu em dois momentos: preparação dos alunos da escola comum e o encontro das duas turmas. Os alunos tiveram informações a respeito da deficiência visual - como lidar com as crianças com deficiência visual, apresentação do Sistema de Leitura e Escrita Braille e de equipamentos pedagógicos. A vivência inclusiva fluiu de maneira muito espontânea e prazerosa, demonstrando a possibilidade de práticas inclusivas de forma constante na vida de cada indivíduo, considerando e respeitando as potencialidades das pessoas com ou sem deficiência.  

  11. A profusão de igrejas entre estudantes do curso de teologia do Izabela Hendrix http://dx.doi.org/10.15601/1983-7631/rt.v3n5p168-173

    Directory of Open Access Journals (Sweden)

    Adilson Schultz

    2011-04-01

    Full Text Available O universo multifacetado das igrejas evangélicas no Brasil está nominalmente representado nos estudantes matriculados no curso de teologia do Centro Universitário Metodista Izabela Hendrix, em Belo Horizonte. No primeiro semestre de 2009 eram cerca de 150 diferentes igrejas ou denominações para um total de 250 alunos ou alunas. Na sala de aula da disciplina Trindade e Teologia da Criação eram 32 diferentes igrejas para um total de 53 alunos e alunas.Esses surpreendentes números elevam o microuniverso escolar ao patamar de caso paradigmático do fenômeno da diversidade religiosa entre evangélicos no Brasil. Dessa forma, permite estudar de forma concentrada nuances do fenômeno religioso evangélico, além de encetar arrazoados teóricos relevantes na teologia e nas ciências da religião. Essa comunicação tem a tarefa de mostrar essa diversidade da filiação religiosa dos estudantes, e sugerir as primeiras formulações para possíveis análises futuras. 

  12. MUNICIPAL STRATEGY FOR LOCAL DEVELOPMENT: THE CASE OF THE STRATEGIC PLANNING OF BLUMENAU-SChttp://dx.doi.org/10.5585/riae.v9i2.1676

    Directory of Open Access Journals (Sweden)

    Sérgio Luiz do Amaral Moretti

    2010-11-01

    Full Text Available Strategic planning (SP is undoubtedly an important tool for the management of municipalities, mainly due to the consequential regulations established by the Fiscal Responsibility Law, and also the City Statute, which exercise constant pressure on local governments. This study proposes to examine the importance of Municipal Strategic Planning (MSP for regional development, and specifically as a means of correlating strategy and the results that shall be achieved. Therefore, we selected the city of Blumenau, SC, which adopted a growth strategy through capitalizing on touristic events based on its German tradition: Oktoberfest, held in the spring and Sommerfest in the summer. The field research adopted the procedure to explore, qualitatively, the case in question through interviews with those directly involved in the decision-making process, within the government and the authorities involved. The results indicate the success of the municipal government and Blumenau’s community in improving its touristic activities concerning the aforementioned events by incorporating an ample SP. In recent years, this collaboration has made an influential contribution to local development.

  13. O uso de jogos oriundos de lojas populares na sala de aula http://dx.doi.org/10.15601/2237-0587/fd.v7n2p37-55

    Directory of Open Access Journals (Sweden)

    Adriana da Silva Fontes

    2015-12-01

    Full Text Available No cenário atual a necessidade formativa dos profissionais, entre os quais, o professor, tem se tornado imprescindível e ponto inicial para um ensino capaz de despertar a construção do conhecimento entre os alunos (GIL-PÈREZ e CARVALHO, 2006. Nessa perspectiva, o estágio supervisionado revela-se como momento em que teoria e prática se entrelaçam propiciando um ensino significativo. Entretanto, a experiência obtida pela ministração de aulas na disciplina de estágio supervisionado obrigatório do curso de formação pedagógica PROFOP/PARFOR, possibilitou constatar a necessidade de instrumentalizar junto ao professor a construção de materiais metodológicos capazes de alcançar os alunos, por meio da adaptação de jogos populares disponíveis no contexto atual. Diante disso, esse artigo tem como intenção destacar a importância do estágio supervisionado na formação do professor, o qual objetiva a formação integral do futuro professor ou professor iniciante, pelo domínio de conteúdo e conhecimento de metodologias e técnicas. E ainda, propiciar durante a disciplina de estágio no PROFOP/PARFOR a análise de jogos existentes oriundos de lojas populares, adaptando-os, confeccionando novos jogos e divulgando os jogos didáticos para que os professores utilizem dentro da sua disciplina. Os resultados indicaram que alunos-professores entenderam como é fácil adquirir/ adaptar/ elaborar jogos, e que é possível utilizar para todas as disciplinas e constataram que os jogos auxiliam os professores no processo de ensino, bem como favorecem a apropriação desses conhecimentos pelo aluno. 

  14. Impactos ambientais e sociais da Copa do Mundo de 2014 http://dx.doi.org/10.15601/1983-7631/rt.v7n12p59-66

    Directory of Open Access Journals (Sweden)

    Marilia Carla de Mello Gaia

    2014-05-01

    Full Text Available Desde a escolha do Brasil, em 2007, para sediar a Copa do Mundo de Futebol de 2014 e as Olimpíadas de 2016, este é um tema recorrente na mídia e em demais espaços de socialização dos brasileiros. Muitas discussões a cerca destes megaeventos esportivos envolvem os benefícios relacionados ao incentivo ao esporte nacional, ao incremento no turismo e na economia e às obras de infraestrutura (sistema de transporte urbano, aeroportos, arenas esportivas, comércio, etc.. A partir das manifestações populares em junho de 2013, principalmente, amplia-se em uma parcela da população brasileira um outro olhar sobre estes eventos esportivos, sobretudo os questionamentos relacionados às necessidades sociais da população em detrimento dos astronômicos investimentos financeiros e políticos para a Copa. Neste contexto, este artigo se destina a discutir alguns elementos envolvidos nos impactos sociais e ambientais da realização da Copa do Mundo de Futebol e das Olimpíadas no Brasil.

  15. Gerenciamento de resíduos químicos em instituições de ensino http://dx.doi.org/10.15601/1983-7631/rt.v2n2p7-18

    Directory of Open Access Journals (Sweden)

    Danielle Arruda Carneiro

    2012-02-01

    Full Text Available Ao longo dos últimos anos, tem crescido bastante o interesse da sociedade pela qualidade do meio ambiente. A geração de resíduos químicos em instituições de ensino e pesquisa sempre foi um assunto muito pouco discutido. Na grande maioria das universidades a gestão dos resíduos gerados nas suas atividades rotineiras é inexistente, por isso o plano de gerenciamento é de grande relevância, uma vez que as universidades contribuem de forma significativa para o desenvolvimento da sociedade. Sua função consiste não só em educar através da transmissão de princípios, mas sim na aplicação destes princípios. O descaso ou despreparo no manejo dos resíduos químicos em diversas instituições leva a graves danos na natureza, os quais podem ter repercussões negativas à saúde humana e ambiental. O objetivo maior dessa revisão bibliográfica é apresentar os critérios básicos para a implementação de um Plano de Gerenciamento de Resíduos nas instituições de ensino.Palavras-chave: resíduos químicos; educação ambiental; saúde pública.

  16. Interação social criança-criança de deficientes visuais http://dx.doi.org/10.15601/1983-7631/rt.v5n9p38-52

    Directory of Open Access Journals (Sweden)

    Sandra Andrade de Castro

    2012-11-01

    Full Text Available O artigo trata de um estudo sobre a interação de crianças de 1 a 3 anos, em uma escola estadual mineira, especializada na educação de deficientes visuais. Utilizou-se a abordagem qualitativa, optando pela inspiração etnográfica e captando as interações por intermédio de observação participante, filmagens, fotografias e registros no caderno de campo. Conforme Gobbi, utilizou-se o termo crianças pequenininhas para aquelas até três anos, considerando, como a Sociologia da Infância, a criança como ator social e participante. Conforme Woods, considerou-se interação social como processo, no qual as pessoas definem, atribuem significados, alinham e realinham suas ações, para  satisfazer seus interesses, comparando-os, ajustando-os e delineando estratégias. Ao final do estudo, observou-se uma oscilação entre a presença ou não da interação entre as crianças. Concluiu-se que, desde tenra idade, as crianças deficientes visuais muito novas são capazes de agir e reagir em direção ao outro, de se colocarem disponíveis para uma interação.

  17. O papel do pedagogo nas organizações DOI: http://dx.doi.org/10.15601/2237-0587/fd.v1n1p19-27

    Directory of Open Access Journals (Sweden)

    Paulo Cabral Junior

    2011-04-01

    Full Text Available Este artigo tem a intenção de mostrar aos graduandos em Pedagogia as várias possibilidades deste profissional no mercado de trabalho. Apesar do foco dos estudos estarem centrados na educação infantil, existe uma grande demanda dos serviços deste profissional em empresas dos mais diferentes seguimentos. Não é objetivo desfazer daqueles que fazem a opção de trabalhar com a alfabetização de crianças, mas sim agregar valor a esta profissão, que apesar de nobre tem pouco reconhecimento até mesmo em seu próprio meio.

  18. História da Fundação do Colégio Metodista Izabela Hendrix DOI: http://dx.doi.org/10.15601/2237-0587/fd.v4n2p16-37

    Directory of Open Access Journals (Sweden)

    Sibeli Martins Santos

    2012-10-01

    Full Text Available Este artigo trata de uma pesquisa com abordagem historiográfica descritiva, no qual foi apresentada a História da fundação do Colégio Metodista Izabela Hendrix. Procura conhecer não só a história desta instituição escolar, como também o contexto histórico-social e político da época de sua fundação, de modo a identificar o contexto histórico da época da fundação do Colégio Metodista Izabela Hendrix, traçar alguns aspectos relevantes do ideário metodista da proposta de Martha Watts em relação ao projeto missionário no Brasil e discutir a importância da fundação do Colégio Metodista Izabela Hendrix para Belo Horizonte. O método utilizado foi o da história cultural tendo como recorte e abordagem a história das instituições escolares dentro da História da Educação, apresentando aspectos históricos, sociais e políticos de Belo Horizonte e do Brasil, no período de 1889 até a fundação do Colégio. A pesquisa tem fontes de natureza bibliográfica tendo como referências autores especializados como: Barreto, Nagle, Mesquita, Mesquida, dentre outros. A pesquisa suscitou a identificação social da clientela e a problemática educacional da época, como também os limites e desafios para a pesquisa.

  19. O bilinguismo como instrumento de inclusão do deficiente auditivo http://dx.doi.org/10.15601/1983-7631/rt.v2n2p19-27

    Directory of Open Access Journals (Sweden)

    Ana Paula Teixeira

    2012-02-01

    Full Text Available A surdez pode ser interpretada como uma privação à "entrada" da linguagem oral e ao desenvolvimento cognitivo decorrente da construção linguística, nesse contexto surge a necessidade de adaptação ao meio e a língua de sinais, que apresenta sua forma de recepção vinculada à visão e sua forma de expressão ao uso de gestos apresenta-se como uma conveniente solução. Por outro lado, o desenvolvimento de novas técnicas científicas já permite ao surdo o ingresso ao mundo dos sons e da fala e a negação do progresso do conhecimento tecnológico é um retrocesso, isso quer dizer que a opção "rígida" pelo uso da língua de sinais pode ser caracterizada como uma atitude desatualizada, ultrapassada. A proposta da educação bilíngue, ou seja, o uso da língua de sinais e da oralidade para os surdos tem se tornado, através desses atuais avanços tecnológicos, uma forma eficaz de inclusão do deficiente auditivo em todo o seu meio social. No entanto, tal proposta ainda não é devidamente empregada nas instituições educacionais e de saúde pública, já que requer um alto investimento político econômico. O objetivo desse trabalho é discutir os alcances da proposta bilíngue e as possíveis formas de sua implementação na educação e na saúde.Palavras-chave: bilinguismo; tecnologia; inclusão social

  20. Aprendizagem e interação social no bilingüismo: revisão de literatura http://dx.doi.org/10.15601/1983-7631/rt.v1n1p32-45

    Directory of Open Access Journals (Sweden)

    Maria Elizabeth Siqueira Lemos

    2012-04-01

    Full Text Available Pesquisar a contribuição do bilingüismo no desenvolvimento da comunicação e da linguagem humana é interesse para a Fonoaudiologia, por ser uma necessidade atual de expansão das habilidades comunicativas. Objetivos: Esta pesquisa buscou entender as diversas variáveis presentes nos processos de aprendizagem, com enfoque no bilingüismo, e refletir sobre a organização cognitiva da criança com deficiência auditiva e os ganhos que poderão ocorrer a partir de sua inserção precoce no bilingüismo. Realizou-se então uma revisão de literatura sobre este tema, a qual incluiu publicações dos últimos 10 anos. Discussão: As informações encontradas neste estudo apontam que as crianças surdas e ouvintes expostas a duas línguas terão maior facilidade em lidar com regras e manipular a gramática de cada uma dessas línguas. Sabe-se que há capacidade de um maior número de estímulos para a aprendizagem por meio do bilingüismo e que ele promove ao ser humano uma vida mais saudável, rica e feliz, pois expande sua visão, seus contatos e possibilidades de exploração do mundo. Comentários Finais: O bilingüismo traz grandes benefícios, um maior número de estímulos às crianças a ele expostas, no entanto, ainda há poucas pesquisas sobre o assunto e pouca abordagem do tema pela Fonoaudiologia.Palavras-chave: bilinguismo; aquisição da linguagem; inteligências múltiplas, deficiência auditiva; aprendizagem; interação social

  1. Da situação do meio estudantil nas sociedades de controle http://dx.doi.org/10.15601/1983-7631/rt.v1n1p84-89

    Directory of Open Access Journals (Sweden)

    Breno Luiz Thadeu da Silva

    2012-04-01

    Full Text Available Desde o final da década de 60 para os dias de hoje, nossos modos de relacionar com o mundo mudaram bastante. No estágio atual do Capitalismo Mundial Integrado, que não se dirige mais para a produção, mas para o mercado, percebemos mudanças radicais nas relações sociais, de trabalho e de ensino. Tecnologias de informação sejam elas digitais ou genéticas, mudaram radicalmente e continuam mudando proporcionando outras redes de contato entres as pessoas e mediações com o mundo. E de todos os lados são identificadas as tão faladas crises das instituições, seja crise da família, escola e ou trabalho. Essas crises e mudanças compactuam com a passagem da sociedade disciplinar para a sociedade de controle. Vamos identificar algumas mudanças que caracterizam essa passagem. Na sociedade disciplinar que conforme identifica Focault e reforça Deleuze, atinge seu auge no início do século XX, o sujeito vive passando de um espaço fechado para outro: primeiro a família, depois a escola e suas continuidades, depois o trabalho (o escritório ou a fábrica, de vez em quando o hospital e talvez a prisão...Esse modelo disciplinar tinha como objetivo organizar e distribuir o tempo-espaço das pessoas para que se conformassem em um conjunto único, facilmente moldável para a produção industrial até para as tomadas de decisões sociais.

  2. Autoimagem corporal: uma revisão sistemática nas diferentes áreas da saúde http://dx.doi.org/10.15601/1983-7631/rt.v6n11p166-177

    Directory of Open Access Journals (Sweden)

    Thaís Mendes Rocha Alves Vieira

    2013-11-01

    Full Text Available Objetivo: Realizar um levantamento sobre a autoimagem corporal nas diferentes revistas da saúde. Métodos: Foram selecionados os principais periódicos das áreas da saúde, no período de 2007 a 2012. A seleção das revistas baseou-se na maior classificação pelo Qualis-Capes. Foram excluídas da análise: revistas internacionais e revistas com classificação inferior à B2. Resultados: Encontrou-se um total de 22 artigos que citam o tema pesquisado. As revistas de Enfermagem, Psicologia e Psiquiatria mencionaram cinco termos em cada, associados à autoimagem corporal; a revista de Nutrição com quatro termos; e a revista de Fonoaudiologia citando dois termos. A cada termo encontrado foram feitas aplicações conforme o assunto abordado. É grande o número de artigos que citam o termo autoimagem correlacionando-os aos distúrbios alimentares. Conclusão: De forma geral, pode-se dizer que há diferentes discussões a respeito do termo autoimagem corporal. Destaca-se que a quantidade de trabalhos abordando o tema é reduzida.   Descritores: Imagem corporal; Autoestima; Autoimagem; Auto-percepção; Revisão sistemática

  3. Methods for assessing physical activity: a systematic review focused on older adults. http://dx.doi.org/10.5007/1980-0037.2013v15n2p256

    Directory of Open Access Journals (Sweden)

    Deisy Terumi Ueno

    2013-03-01

    Full Text Available Among the large array of instruments for measuring physical activity (PA, the use of questionnaires, pedometers, and accelerometers with older adults is frequent. This study aimed to analyze the most widely adopted protocol for each instrument that is most commonly used to assess PA in older adults, and explore possible advantages and disadvantages of the methods used for these instruments. Thereby, we performed a search in databases and cross references of the articles selected. This procedure yielded in 16 studies being included. The in-depth analyzed studies demonstrate that questionnaires are usually applied either as an interview or self-administered, assessing the domains of leisure, sports, and household chores with a recall period of a typical week in the last month. Regarding pedometers and accelerometers, the length of time considered to be sufficient for data collection is five days. The devices are frequently used on the waist or hip with a belt or attached to clothing and removed only for water activities or during sleeping time. The use of either instrument should take into account the advantages and disadvantages that influence choosing one over the other, such as the number of participants to be evaluated, the time available for assessment, among others. The use of accelerometer along with PA questionnaire may yield more reliable and accurate measurements of PA level. In addition, it is recommended that, for older adults, questionnaires should be applied employing the interview format, in order to minimize possible misinterpretation of the questions.

  4. Produção musical, consumo cultural e extensão universitária http://dx.doi.org/10.15601/1983-7631/rt.v8n15p12-88

    Directory of Open Access Journals (Sweden)

    Neylson João Batista Filho Crepalde

    2015-12-01

    Full Text Available O presente trabalho tem por objetivo apresentar o projeto de extensão “Produção de eventos artísticos” desenvolvido pelo curso de Música do CEUNIH contextualizando-o nas diretrizes educacionais nacionais e locais relativas à extensão. Apresento ainda os primeiros resultados de um programa de pesquisa em desenvolvimento no projeto. Utilizando o método análise de componentes principais (PCA analisei os dados coletados criando algumas variáveis latentes que sintetizam as respostas do questionário relacionadas ao consumo de eventos artísticos em Belo Horizonte. Por fim, discuto algumas possibilidades da extensão universitária na área da educação musical. Palavras-chave: Extensão universitária; produção de eventos artísticos; consumo de eventos artísticos; socioeconomia da arte; análise de componentes principais

  5. Estresse em familiares de crianças com transtornos do aprendizado http://dx.doi.org/10.15601/1983-7631/rt.v4n6p66-73

    Directory of Open Access Journals (Sweden)

    Renata Mousinho

    2011-05-01

    Full Text Available Introdução: Considerando-se a criança parte ativa no núcleo familiar, um déficit na leitura provoca efeitos em toda a família. O baixo rendimento escolar decorrente de dislexia ou distúrbio de aprendizagem pode aumentar o nível de estresse dos familiares.   Metodologia: participaram do projeto de pesquisa dezesseis responsáveis por crianças atendidas no Ambulatório de Transtornos da Língua Escrita, INDC-UFRJ. Foram utilizados dois questionários, sendo um estruturado: estresse, versão reduzida e um questionário específico de problemas de aprendizagem, semi-aberto, calcado nas dificuldades relatadas pelas famílias na prática clínica. Nos dois casos, as respostas deveriam ser dadas considerando-se os momentos antes e depois do diagnóstico. Resultados: foram reveladas correlações estatísticas (Pearson entre os itens dos dois questionários: significância estatística entre estresse x melhores resultados escolares e estresse x compreensão da escola. Na comparação entre o momento antes e depois do diagnóstico, evidenciou-se decréscimo substancial do impacto do estresse nos seguintes aspectos e momentos: durante o período de provas, na relação com a escola, na baixa auto-estima/ sofrimento da criança, nas terapias de apoio, em relação ao julgamento dos outros, na implicância de colegas, e na não compreensão da própria dificuldade. Conclusão: Transtornos do Aprendizado  podem ser fonte de estresse na família. A compreensão da escola somada aos melhores resultados escolares ajudam a diminuí-lo. O diagnóstico, associado à compreensão das dificuldades, é um período em que a redução se torna mais visível. Tais dados confirmam que é um importante momento para oferecer esclarecimento e apoio aos familiares.Palavras-chave: transtornos do aprendizado;família; estresse

  6. Identifying ventilatory anaerobic threshold in children and adolescents: A literature review. DOI: http://dx.doi.org/10.5007/1980-0037.2012v14n3p343

    Directory of Open Access Journals (Sweden)

    Luciana Carletti

    2012-05-01

    Full Text Available Ventilatory anaerobic threshold (VAT has been used in research to represent pulmonary function and submaximal performance capacity of children and adolescents. This study aimed to identify: a the group of children and adolescents that has been the main focus of research; b the criteria most commonly used to determine VAT; and c the main references that have been used to support the theoretical analysis. A literature search was conducted using LILACS, MEDLINE/PubMed, and SciELO. The search was limited to studies using VAT in their methodology, published between 2000 and 2010, in order to identify categories through content analysis. Descriptive statistics were used to analyze the data. Forty-five studies were found and distributed according to categories identified, as follows: severe exercise intolerance (23 [51%]; healthy subjects (6 [13%]; obese subjects and comparison of methodologies (4 [9%], each; O2 kinetics (3 [7%]; sports (2 [4%]; stunting, asthma, and effort perception (1 [2%], each. The main reference used is Beaver WL, Wasserman K, Whipp BJ (1986, cited in 24 (53% studies, and the main criterion for VAT determination is the V-slope method. In addition to this method, ventilatory equivalents for O2 and CO2 have been used, accounting for 37% (17 of cases. In conclusion, the dataindicate that VAT has been primarily used in rehabilitation studies including children and adolescents by the V-slope method.

  7. Can neuromuscular fatigue threshold bedetermined by short and non-exhaustive bouts?. DOI: http://dx.doi.org/10.5007/1980-0037.2012v14n3p254

    Directory of Open Access Journals (Sweden)

    Alexandre Hideki Okano

    2012-05-01

    Full Text Available The present study determined the neuromuscular fatigue threshold (NFT using four different time-periods of analysis of the electromyographic signal and compared these estimations with critical power (CP. Fifteen healthy young men (73.6 ± 5.1 kg, 177.8 ± 7.0 cm, 23.4 ± 5.2 years performed 3-4 different severe constant workload trials until exhaustion on a cycle ergometer with simultaneous SEMG signals acquisition. The obtained data permitted NFT estimation with four different periods of analysis as follows: initial 30s (T30, 1min (T1, 2min (T2 and total time (TT, as well as CP. T30 and T1 were significantly higher than TT and CP and, T2 and TT did not differ between each other, and both were significantly higher than CP. In addition, TT was significantly correlated to CP (0.72; P < 0.05 and to T2 (0.58; P < 0.05. We conclude that NFT overestimates CP, independent of the time-period analysis used for its determination.

  8. Adolescência, infração e serviço social http://dx.doi.org/10.15601/1983-7631/rt.v3n4p48-60

    Directory of Open Access Journals (Sweden)

    Jaqueline Lago

    2011-04-01

    Full Text Available O objetivo deste artigo foi o de analisar uma pequena faceta da adolescência em face da sua responsabilização perante o Estatuto da Criança e do Adolescente (ECA pela prática de atos infracionais. O trabalho contempla uma abordagem sobre as medidas socioeducativas, em especial sobre a internação de adolescentes e discute temas relevantes, tais como: o ato infracional, a educação, o Serviço Social, o ECA e os aspectos constitucionais pertinentes. Discorre-se, também, sobre a importância do processo socioeducativo nas Unidades de internação e sobre o papel do profissional de Serviço Social neste contexto. O trabalho foi realizado através de pesquisa teórico-bibliográfica e documental, sendo utilizado o método hipotético-dedutivo.Palavras-chave: adolescência; medidas socioeducativas; educação; serviço social; ECA

  9. Thiolation-enhanced substrate recognition by D-alanyl carrier protein ligase DltA from Bacillus cereus [v1; ref status: indexed, http://f1000r.es/3dx

    Directory of Open Access Journals (Sweden)

    Liqin Du

    2014-05-01

    Full Text Available D-alanylation of the lipoteichoic acid on Gram-positive cell wall is dependent on dlt gene-encoded proteins DltA, DltB, DltC and DltD. The D-alanyl carrier protein ligase DltA, as a remote homolog of acyl-(coenzyme A (CoA synthetase, cycles through two active conformations for the catalysis of adenylation and subsequent thiolation of D-alanine (D-Ala. The crystal structure of DltA in the absence of any substrate was observed to have a noticeably more disordered pocket for ATP which would explain why DltA has relatively low affinity for ATP in the absence of any D-alanyl carrier. We have previously enabled the thiolation of D-alanine in the presence of CoA as the mimic of D-alanyl carrier protein DltC which carries a 4’-phosphopantetheine group on a serine residue. Here we show that the resulting Michaelis constants in the presence of saturating CoA for both ATP and D-alanine were reduced more than 10 fold as compared to the values obtained in the absence of CoA. The presence of CoA also made DltA ~100-fold more selective on D-alanine over L-alanine. The CoA-enhanced substrate recognition further implies that the ATP and D-alanine substrates of the adenylation reaction are incorporated when the DltA enzyme cycles through its thiolation conformation.

  10. O ALONGAMENTO E O AQUECIMENTO INTERFEREM NA RESPOSTA NEUROMUSCULAR? UMA REVISÃO DE LITERATURA - DOI: http://dx.doi.org/10.18511/0103-1716/rbcm.v21n1p158-165

    OpenAIRE

    Wouber Hérickson de Brito Vieira; Departamento de Fisioterapia – Universidade Federal do Rio Grande do Norte (UFRN); João Felipe de Souza Nogueira; Programa de Pós-Graduação Lato Senso em Fisioterapia Ortopédica e Desportiva - FARN; Jéssica Cardoso de Souza; Programa de Mestrado e Doutorado - Universidade Católica de Brasília (UCB); Jonato Prestes; Programa de Mestrado e Doutorado - Universidade Católica de Brasília

    2013-01-01

    O alongamento e o aquecimento são comumente utilizados antes de qualquer atividade esportiva, seja ela competitiva ou recreacional. O objetivo do presente estudo foi realizar uma breve revisão da literatura, dos últimos 15 anos, a respeito da influência do alongamento e aquecimento na resposta neuromuscular. Para essa análise foram utilizados periódicos das seguintes bases bibliográficas: Pubmed, Scielo, Isi Web of Knowledge e Lilacs. Os artigos revisados mostram que o aquecimento pode, por m...

  11. THE INFLUENCE OF CULTURAL DISTANCE WHEN CHOOSING A SUITABLE FOREIGN DIRECT INVESTMENT FOR THE INTERNATIONALIZATION PROCESS OF COMPANIES. A THEORETCAL OVERVIEWhttp://dx.doi.org/10.5585/riae.v10i1.1712

    Directory of Open Access Journals (Sweden)

    Ivani Ferreira

    2011-06-01

    Full Text Available The present study is theoretical analysis on the influence that cultural distance (CD may possess on the process of internationalization of companies, and country cost representing this variable; comparing the arguments of the transaction cost theory and the organizational capability theory, with the purpose of determining which form of foreign direct investment (FDI is most appropriate when companies are directed to culturally distant countries. Two types of FDI strategies are discussed in this study: a WOS (Wholly Owned Subsidiary, for companies wishing to expand their business into culturally distant countries, but with a lower risk; and an IJV (International Joint Venture, for companies wishing to expand their business into culturally distant countries, but with a higher risk to the company. This study describes two opposing positions attempting to converge when a moderator variable is included: country risk. Thus, we shall look to build a thorough model of analysis, where the earlier theories are complemented to explain the entrepreneurial performance following various scenarios, in which the involved variables are, concurrently, the cultural distance and country risk.

  12. UM ESTUDO COMPARATIVO DO GRAU DE SUSTENTABILIDADE EMPRESARIAL DA COTRIBETA ENTRE 2006 E 2010http://dx.doi.org/10.5585/riae.v9i2.1667

    Directory of Open Access Journals (Sweden)

    Elvis Silveira Martins

    2010-11-01

    Full Text Available O objetivo da presente pesquisa foi o de comparar o grau de sustentabilidade corporativa da Cooperativa Tritícola Gaúcha Cotribeta nos anos de 2006 e 2010, utilizando o Modelo de Planejamento Estratégico para a Sustentabilidade Empresarial – PEPSE desenvolvido por Coral (2002. Este período foi considerado no presente estudo pelo fato da empresa estudada ter passado por diversas turbulências mercadológicas, e assim, buscou-se compreender se estas mudanças de cenário impactaram no índice de sustentabilidade. O trabalho foi estruturado com base em uma pesquisa qualitativa, valendo-se do estudo de caso; as informações foram coletadas por meio de entrevistas semi-estruturadas em 2006 e 2010. A empresa obteve um declínio no grau de referência da dimensão ambiental e social, sendo que em 2006 o grau de sustentabilidade empresarial da Cotribeta havia sido classificado como potencial sustentável regular e em 2010 como potencial sustentável crítico.

  13. Processo de gestão e liderança nas empresas familiares http://dx.doi.org/10.15601/1983-7631/rt.v9n16p57-69

    Directory of Open Access Journals (Sweden)

    Patricia Silva da Silva

    2016-06-01

    Full Text Available O Brasil tem entre 6 a 8 milhões de empresas, sendo que 90% delas são empresas familiares, configurando papel significativo no desenvolvimento econômico, social e mesmo político no país (SEBRAE, 2015. Este artigo analisa a gestão e o exercício da liderança nas empresas familiares a partir de estudo de caso. Os objetivos da investigação são compreender o processo de gestão e desenvolvimento dos líderes nestas organizações O método adotado é qualitativo-descritivo, a partir de estudo de caso em empresa do setor varejista. A empresa analisada caracteriza-se pela gestão centralizada, observando-se dificuldades de comunicação. Na visão dos participantes, as empresas familiares possibilitam maior crescimento profissional e reconhecimento, pela proximidade com a direção, em oposição às corporações de controle acionário. A resistência à mudança pelos gestores familiares implica em tempo ampliado para algumas ações, o que preocupa as lideranças em relação ao futuro da empresa, diante do cenário externo altamente competitivo.

  14. PRÁTICAS CORPORAIS E USO DE ÁLCOOL E DROGAS: VIVENCIANDO EMOÇÕES - DOI: http://dx.doi.org/10.18511/0103-1716/rbcm.v22n2p141-147

    OpenAIRE

    Priscilla Pinto Costa Silva; Universidade de Pernambuco; Ana Raquel Mendes Santos; Emília Amélia Pinto Costa Silva; Universidade Federal do Paraná; Ameliane Conceição Reubens Leonidio; Universidade de Penambuco; Bruno Medeiros Roldão Araújo; Universidade Federal de Campina Grande; Clara Maria Silvestre Monteiro Freitas; Universidade de Pernambuco

    2014-01-01

    The use of psychoactive drugs, as well as bodily practices may generate different emotions, positive or negative, which may contribute to the formation of the being. Thus, the search for new sensations awakens the desire by the new and the forbidden, especially in adolescence, which may lead the social actors to experience alcohol and other substances. The increased consumption of psychoactive drugs in urban centers becomes worrisome, allowing bodily practices to work focusing on prevention a...

  15. Literatura e religião: entre o tudo-dizer e o nada-dizer [do poder-ser] http://dx.doi.org/10.15601/1983-7631/rt.v5n8p48-60

    Directory of Open Access Journals (Sweden)

    Luiz Carlos Mariano da Rosa

    2012-05-01

    Full Text Available Detendo-se inicialmente na relação que envolve o horizonte teológico e as fronteiras literárias no arcabouço bíblico, o artigo em questão procura distinguir o tipo de linguagem que caracteriza a corporalidade textual deste último, assinalando a função que cumpre a escrita/escritura no âmbito do monoteísmo, que encerra, em suma, a história da emergência de um “Deus único”, sob cuja perspectiva, à possibilidade que acena com uma aproximação entre teologia e literatura se impõe um método, como o propõe Antônio Magalhães através do “caminho da correspondência”, que o referido trabalho sublinha, convergindo para analisar o conto Via crucis, de Clarice Lispector, que mantém a Bíblia e a tradição na condição de interlocução do diálogo e exemplifica o fenômeno da “poética da mitologização”.

  16. Pensar a cibercultura ambientalista: potencialidades da comunicação e da mobilização virtual http://dx.doi.org/10.15601/1983-7631/rt.v4n7p1-13

    Directory of Open Access Journals (Sweden)

    Katarini Giroldo Miguel

    2011-10-01

    Full Text Available O presente artigo propõe uma discussão prático-teórica relacionada à cibercultura do movimento ambientalista, avaliando a experiência comunicativa e o potencial transformador e mobilizador dos conteúdos digitais. Neste sentido, para complementar o arcabouço teórico e explorar o tema, o artigo apresenta uma análise descritiva e preliminar da homepage de uma das maiores ONGs (Organização Não Governamental ambientais, o Greenpeace, na tentativa de compreender o funcionamento de ferramentas virtuais como o ciberativismo e as redes sociais, levantando aqui questionamentos sobre a construção da comunicação ambiental na internet, suas diferenciações e possíveis impactos na sociabilidade

  17. Relationship between month of birth and height of athletes in the under 17 World Cup. DOI: http://dx.doi.org/10.5007/1980-0037.2012v14n5p571

    Directory of Open Access Journals (Sweden)

    Luiz Carlos Couto de Albuquerque Moraes

    2012-09-01

    Full Text Available The Relative Age Effect, which consists in the advantage obtained by an athlete born closer to the beginning of the year selection, is shown as an important variable for the development of talent, particularly due to maturational aspects. The objective of this study was to analyze the distribution of the birth dates of the soccer players participating in the Under 17 World Championship, and verify the differences in their height. In order to do so, data referring to 1479 athletes registered in the last three competitions (2007, 2009 and 2011 was collected from the official FIFA site. Subsequently, the corresponding data was divided into birth date quartiles and also zone position of the field. For the comparison of proportional representativeness of each birth date quartile, it was used the chi-squared test with Bonferroni correction. The ANOVA factorial 2x2 was applied to compare the heights by birth date quartile and by zone position of the field. A Spearman correlation analysis was also used to verify the association between the variables. Differences were found in the distribution of birth date quartiles, with a predominance of athletes born in the first and second quartiles; and in the height of the athletes, having athletes who were born in the first and second quartiles a higher average height. It was concluded that the relative age effect is a factor that may influence the selection of soccer players and that influences the height (a maturational variable.

  18. O papel do enfermeiro na assistência ao paciente oncológico http://dx.doi.org/10.15601/1983-7631/rt.v2n3p95-104

    Directory of Open Access Journals (Sweden)

    Nilda Alves Miranda Amâncio

    2011-12-01

    Full Text Available Este é um estudo de revisão sistemática que aborda a oncologia. Qual o papel do enfermeiro na assistência ao paciente oncológico foi o problema estudado. Os objetivos foram: verificar em artigos científicos recentes os desafios do enfermeiro na assistência ao paciente oncológico, buscando a melhoria na qualidade do atendimento e identificar se o enfermeiro proporciona conforto para o paciente e a família dando apoio psicosocial; identificar como o enfermeiro cuida do paciente com dor crônica; verificar se o enfermeiro informa o paciente oncológico sobre o prognóstico fora de possibilidade terapêutica. A metodologia utilizada para o estudo foi o de pesquisa de revisão sistemática. Foram utilizados artigos de periódicos das seguintes bases eletrônicas: SCIELO(Scientific Eletronic Library, LILACS(Literatura Latino-Americana e do Caribe em Ciências da Saúde, MEDLINE(Literatura Internacional em Ciências da Saúde, publicados no período de 1991 a 2008, em idioma português, espanhol e inglês. Na apresentação e discussão dos resultados constatamos que o conhecimento em oncologia é escasso. Falta este conteúdo na grade curricular da graduação.Palavras-chave: enfermeiro; assistência; paciente oncológico

  19. Electromyographic activity and scapular dyskenesia in athletes with and without shoulder impingement syndrome. http://dx.doi.org/10.5007/1980-0037.2013v15n2p193

    Directory of Open Access Journals (Sweden)

    Rodrigo Cappato de Araújo

    2013-03-01

    Full Text Available The objective of this study was to evaluate the presence of scapular dyskinesis and pain, satisfaction and function levels, as well as analyze the activation of scapular stabilizing muscles during isometric tasks of shoulder abduction in athletes with and without SIS. Thirty men athletes were divided into two groups: SIS group and Control group. The volunteers answered the Penn Shoulder Score questionnaire translated into Portuguese, which evaluates pain, dysfunction, and satisfaction with the shoulder. They were also evaluated for the presence of scapular dyskinesis through the Slide Scapular Lateral Test. The electromyographic activity of the upper trapezius (UT, middle trapezius (MT, lower trapezius (LT, and serratus anterior (SA muscles was evaluated during the isometric shoulder abduction in the frontal and scapular planes at angles of 45º, 90°, and 120°. The SIS group had a higher indication of pain and scapular dyskinesis when compared to control group. In the SIS group, higher values of electromyographic ratios between UT/LT and UT/SA were observed in the frontal plane in relation to the scapular plane. The conclusion can be made that pain, scapular dyskinesis, and altered muscle activation pattern was more frequent in the SIS group compared to the Control group. Therefore, exercises that emphasize the scapular muscles should be considered when planning rehabilitation programs for the SIS.

  20. O desafio da efetivação do direito à cidade nas metrópoles http://dx.doi.org/10.15601/1983-7631/rt.v4n7p58-70

    Directory of Open Access Journals (Sweden)

    Natalia Cardoso Marra

    2011-10-01

    Full Text Available Todos têm direito à cidade, mas, contraditoriamente, o acesso a esse direito não é disponibilizado de forma igualitária. A gestão urbana das metrópoles deve se dar de maneira intersetorializada, conectada com os fatores de formação do espaço urbano, contudo não é dessa maneira que as cidades são organizadas. O déficit habitacional no Brasil demonstra o descaso dos administradores públicos frente a um fator essencial para a formação do espaço urbano e para a vida. Esse trabalho visa demonstrar através de um estudo da ineficiente efetivação do direito social à moradia como é falha a gestão das metrópoles, apontando as possibilidades e os desafios da participação popular como instrumento de acesso à cidade. Palavras-chave: gestão urbana; moradia; direito à cidade; governança; participação popular

  1. A educação de sujeitos como programa para superar a crise espiritual do nosso tempo http://dx.doi.org/10.15601/1983-7631/rt.v3n5p108-126

    Directory of Open Access Journals (Sweden)

    Adilson Schultz

    2011-04-01

    Full Text Available Os processos de ensino-aprendizagem lidam continuamente com a pergunta pelo sentido da educação formal e da tarefa docente. “Quem precisa de nós?” A resposta a essa questão começa com o diagnóstico da situação geral do nosso tempo, sua caracterização política, social e cultural, especialmente naquilo que toca a tarefa docente: Aspectos das relações trabalhistas, especialmente as incertezas propugnadas no contexto do capitalismo flexível; aspectos das relações político-pessoais, especialmente os ditames éticos e morais, entre eles a pressão financista, que associa a educação formal a sucesso profissional; aspectos das relações culturais-civilizacionais – ou espirituais, no sentido do espírito do nosso tempo. A fim de dar conta da situação atual considerando esses três aspectos, o texto que segue propõe um trajeto por três autores clássicos da sociologia e da filosofia: Richard Sennett e sua obra “A corrosão do caráter”; Alain Touraine e sua obra “Poderemos viver juntos?”, e Karl Jaspers e sua obra “A situação espiritual do nosso tempo.” Os três autores tratam, cada qual a seu modo, da crise civilizacional que ameaça a humanidade. Em Sennett ficará evidente como a precarização do trabalho e das relações trabalhistas desencadeia processos que podem corroer o que docentes e discentes tem de mais precioso a desenvolver na estrutura de ensino aprendizagem, qual seja, a formação do caráter. Em Touraine veremos como para além da simples crítica ao processo de flexibilização do trabalho no capitalismo, e para além dos falsos remédios à disposição, quais sejam, a adesão à cultura da massa indiferenciada, ou o isolamento na tribo ou gueto, é possível a formulação de um caminho baseado na educação de sujeitos, uma espécie de 3a via. Já na formulação de Karl Jaspers, um caminho denominado “constituição do ser-si-próprio”, onde somos todos desafiados à constituição do ser no mais profundo da existência. Justapostos e tomados em conjunto, as obras criam um caminho teórico para responder às questões colocadas sobre o sentido da educação e da tarefa docente, o para que e o para quem da docência.Palavras-chave: educação de sujeitos; ser-si-próprio; corrosão do caráter; Karl Jaspers; Alain Touraine; Richard Sennett

  2. Abordagem tecnológica para rastreio de pessoas com dislexia http://dx.doi.org/10.15601/1983-7631/rt.v4n6p41-53

    Directory of Open Access Journals (Sweden)

    Raimundo José Macário Costa

    2011-05-01

    Full Text Available Resumo. O objetivo deste artigo é apresentar um sistema “inteligente” desenvolvido para rastrear pessoas com dislexia e a comorbidade TDAH associada. Este rastreio se faz através de classificação probabilística, usando redes neurais artificiais. As pessoas, uma vez identificadas, podem ser encaminhadas para atendimento específico, intervenções precoces, de modo, a minimizar o comprometimento da aprendizagem escolar.Palavras-chave: dislexia; aprendizagem; rede neural; inteligência artificial

  3. Já temos o legado da copa: o movimento de indignação das ruas! http://dx.doi.org/10.15601/1983-7631/rt.v6n10p1-3

    Directory of Open Access Journals (Sweden)

    Adilson Schultz

    2013-06-01

    Full Text Available O pensador e educador Paulo Freire tem um livro com esse título: “Pedagogia da indignação”. Que belo par esse título faz com seus outros livros de Pedagogia... do oprimido, da esperança, da autonomia, da indignação... O livro traz, entre outros estudos, as últimas duas páginas escritas pelo renomado professor, poucos dias antes de sua morte, em 22.04.97, onde ele mostra toda sua indignação frente à morte do líder indígena pataxó Galdino Jesus dos Santos, que foi queimado vivo por cinco jovens, em 20.04.1997, enquanto dormia num ponto de ônibus em Brasília.

  4. Performance comparison of resistance-trained subjects by different methods of adjusting for body mass. DOI: http://dx.doi.org/10.5007/1980-0037.2012v14n3p313

    Directory of Open Access Journals (Sweden)

    Wladymir Külkamp

    2012-05-01

    Full Text Available The aim of this study was to compare the performance (1RM of resistance-trained subjects, using different methods of adjusting for body mass (BM: ratio standard, theoretical allometric exponent (0.67, and specific allometric exponents. The study included 11 male and 11 female healthy non-athletes (mean age = 22 years engaged in regular resistance training for at least 6 months. Bench press (BP, 45° leg press (LP and arm curl (AC exercises were performed, and the participants were ranked (in descending order according to each method. The specific allometric exponents for each exercise were: for men – BP (0.73, LP (0.35, and AC (0.71; and for women – BP (1.22, LP (1.02, and AC (0.85. The Kruskal-Wallis test revealed no differences between the rankings. However, visual inspection indicated that the participants were often classified differently in relation to performance by the methods used. Furthermore, no adjusted strength score was equal to the absolute strength values (1RM. The results suggest that there is a range of values in which the differences between exponents do not reflect different rankings (below 0.07 points and a range in which rankings can be fundamentally different (above 0.14 points. This may be important in long-term selection of universally accepted allometric exponents, considering the range of values found in different studies. The standardization of exponents may allow the use of allometry as an additional tool in the prescription of resistance training.

  5. Valores organizacionais e serviços terceirizáveis: uma análise interna http://dx.doi.org/10.15601/1983-7631/rt.v2n2p40-51

    Directory of Open Access Journals (Sweden)

    Denilson Aparecida Leite Freire

    2012-02-01

    Full Text Available O artigo pretendeu demonstrar a possível relação que se possa estabelecer entre os valores organizacionais expressos pela alta administração e aqueles explicitados pelos colaboradores, em uma empresa do setor de serviços terceirizáveis. A estratégia metodológica baseou-se no tipo de pesquisa descritiva, através do método de estudo de caso. Para se medir os valores organizacionais foi aplicado o modelo de questionário idealizado por Tamayo, Mendes e Paz (2000, denominado de Inventário de Valores Organizacionais (IVO. Os resultados revelaram que existe relação entre os valores organizacionais dos colaboradores com os da alta administração. Espera-se que estes resultados possam contribuir para a melhoria dos processos de gestão dos profissionais que atuam nas empresas pertencentes ao setor de serviços terceirizáveis.Palavras-chave: cultura organizacional; valores organizacionais; setor de serviços; serviços terceirizáveis

  6. O humanismo em crise: a proposta levinasiana da alteridade do rosto como reconstrução do humanismo http://dx.doi.org/10.15601/1983-7631/rt.v5n9p18-29

    Directory of Open Access Journals (Sweden)

    Rafael Soares Duarte de Moura

    2012-11-01

    Full Text Available O pensamento levinasiano procurou responder ao soerguimento de uma razão estruturalista que resignou o homem a um conceito abstrato, frágil e fechado em sua individualidade existente.   O presente trabalho procura problematizar a abordagem de Emmanuel Lévinas sobre a crise do humanismo. Essa crise será apresentada por meio do pensar a construção do indivíduo, encastelado em si mesmo, por meio da análise das correntes de pensamento racional-estruturalistas e da ontologia desenvolvida pela metafísica de inspiração idealistas.   Serão tematizados os limites da razão para o desenvolvimento de um humanismo levinasiano. Nesse sentido, a superação da dicotomia sujeito-objeto por meio do agir humano será pensada como forma de se redescobrir o Ser que procura encontrar a dignidade e fazer a experiência concreta do sentido do existir.

  7. Da formação inicial ao ingresso na carreira docente DOI: http://dx.doi.org/10.15601/2237-0587/fd.v8n1p5-25

    Directory of Open Access Journals (Sweden)

    Klinger Teodoro Ciríaco

    2016-05-01

    Full Text Available O presente artigo tem como objetivo apresentar dados de uma pesquisa exploratória desenvolvida com egressos do curso de Pedagogia da Universidade Federal de Mato Grosso do Sul – UFMS/Câmpus de Naviraí – na perspectiva de compreender contribuições da formação inicial para os dilemas e dificuldades enfrentados no processo de inserção na carreira. Para tal, desenvolvemos um estudo de cunho qualitativo que se baseou em dados obtidos via análise de respostas de questionários aplicados com um grupo de professores iniciantes. Por fim, com a conclusão do estudo, podemos concluir que se faz necessário à criação políticas públicas que visem à promoção e apoio à inserção na carreira, bem como para a permanência na profissão.

  8. Sobre a noção de verdade: da adequação à ontologia de Martin Heidegger http://dx.doi.org/10.15601/1983-7631/rt.v5n9p10-17

    Directory of Open Access Journals (Sweden)

    Leonardo Goulart

    2012-11-01

    Full Text Available Este artigo trata de apresentar os fundamentos da ontologia para Martin Heidegger enquanto noção fundamental para compreensão da noção de verdade. Para tanto busca diferenciar a noção tradicional da verdade como adequação da perspectiva heideggeirana sobre verdade apoiada na compreensão do ser e da liberdade.  

  9. Properties of the relaxation time distribution underlying the Kohlrausch-Williams-Watts photoionization of the DX centers in Cd{sub 1-x}Mn{sub x}Te mixed crystals

    Energy Technology Data Exchange (ETDEWEB)

    Trzmiel, J; Weron, K; Placzek-Popko, E [Institute of Physics, Wroclaw University of Technology, Wybrzeze Wyspianskiego 27, 50-370 Wroclaw (Poland); Janczura, J [Hugo Steinhaus Center for Stochastic Methods and Institute of Mathematics and Computer Science, Wroclaw University of Technology, Wybrzeze Wyspianskiego 27, 50-370 Wroclaw (Poland)

    2009-08-26

    In this paper we clarify the relationship between the relaxation rate and relaxation time distributions underlying the Kohlrausch-Williams-Watts (KWW) photoconductivity build-ups in indium- and gallium-doped Cd{sub 1-x}Mn{sub x}Te mixed crystals. We discuss the role of asymptotic properties of the corresponding probability density functions. We show that the relaxation rate distribution, as a completely asymmetric alpha-stable distribution, leads to an infinite mean value of the effective relaxation rate. In contrast, the relaxation time distribution related to it leads to a finite mean value of the effective relaxation time. It follows from the experimental data analysis that for all the investigated samples the KWW exponent alpha decreases linearly with increasing photon flux in the range of (0.6-0.99) and its values are more spread in the case of gallium-doped material. We also observe a linear dependence of the mean relaxation time on the characteristic material time constant, which is consistent with the theoretical model.

  10. Prevalence of self-reported morbidity and knowledge about diabetes: population-based study in Southern Brazil. DOI: http://dx.doi.org/10.5007/1980-0037.2012v14n5p562

    Directory of Open Access Journals (Sweden)

    Alan Goularte Knuth

    2012-09-01

    Full Text Available The aim of the present study was to evaluate the knowledge about diabetes and the prevalence of self-reported diabetes in the city of Pelotas, Brazil. A population-based cross-sectional study was carried out including 972 subjects aged from 20 to 69 years. The prevalence of self-reported diabetes was 5.3% (95% CI: 3.9% – 6.7%. Most individuals (73.4% considered that physical exercise is beneficial for diabetic patients. Approximately 90% of the sample correctly identified the characteristics of diabetes, and greater knowledge was observed among those aged 20 to 49 years and from high socioeconomic status. More than half of the sample (54.9% correctly identified the risk factors for diabetes and greater knowledge was observed among females and subjects from high socioeconomic level. Kno­wledge on diabetes seems to be widespread among the population, although it is marked, mainly, by socioeconomic differences. Government health promotion strategies are urgent to raise awareness about this morbidity in the population.

  11. Assistência de enfermagem ao paciente portador de esquizofrenia: o desafio do cuidade em saúde mental http://dx.doi.org/10.15601/1983-7631/rt.v2n3p30-40

    Directory of Open Access Journals (Sweden)

    Ellen Filgueiras de Faria

    2011-12-01

    Full Text Available A esquizofrenia é uma doença mental que acomete as emoções, o pensamento, as percepções e o comportamento das pessoas acometidas. Atualmente é um problema de saúde pública, que após a reforma psiquiátrica brasileira, assumiu definitivamente o papel da assistência ao portador de sofrimento mental. A enfermagem possibilita através de suas ações de cuidado e assistência uma maior inserção do esquizofrênico na sociedade. Neste estudo realizamos uma revisão bibliográfica a fim de verificar qual a importância da assistência de enfermagem ao portador de esquizofrenia. Os dados obtidos permitiram observar que o enfermeiro tem um papel fundamental na vida do esquizofrênico, criando um tratamento individualizado e diferenciado, que envolve a família e a comunidade, sempre visando ampliar assistência à família e ao paciente de maneira humanizada e novas formas de abordagem, evitando assim a gravidade das recaídas dos sintomas.Palavras-chave: esquizofrenia; assistência de enfermagem; saúde mental

  12. Training load, stress tolerance and upper respiratory tract infection in basketball players. http://dx.doi.org/10.5007/1980-0037.2013v15n1p49

    Directory of Open Access Journals (Sweden)

    Camila Gobo Freitas

    2013-01-01

    Full Text Available The present study aimed to investigate the effect of external training load manipulation on internal training load (ITL, stress tolerance (ST and upper respiratory tract infection (URTI severity in basketball players during a 19-week macrocycle. The macrocycle was divided into three distinct phases: preparatory phase (P1 and two competitive phases (P2 and P3. The Daily Analysis of Life Demands for Athletes questionnaire (DALDA, for assessment of sources and symptoms of stress, and the Wisconsin Upper Respiratory Symptom Survey (WURSS-21, for evaluation of URTI severity, were used on a weekly basis. The ITL was assessed by Rating of Perceived Exertion (session RPE. There was a decrease in ITL at P3 when compared to P1 and P2 (p < 0.05. A decrease in “better than normal” responses in DALDA for both sources and symptoms of stress was observed at P2 and P3 when compared to P1 (p < 0.05. There was also a significant increase in URTI severity. In addition, significant relationships between ST and URTI were shown at P3, suggesting that stress tolerance may modulate URTI severity. In summary, ETL manipulation induced changes in ITL. However, unlike the initial hypothesis, a decrease in ITL during the competitive period was followed by a decrease in stress tolerance and an increase in URTI severity. Furthermore, the magnitude of stress seems to provoke an increase in URTI severity.

  13. Modos de vida alternativos: o caso da comunidade Noiva do Cordeiro http://dx.doi.org/10.15601/1983-7631/rt.v3n5p152-158

    Directory of Open Access Journals (Sweden)

    Adilson Schultz

    2011-04-01

    Full Text Available Noiva do cordeiro é uma comunidade rural liderada por mulheres, que desenvolveu um modo de vida alternativo e sustentável, com partilha de bens e fim da religião institucionalizada. Forjado ao longo de mais de um século, num processo de constantes rupturas religiosas, familiares e ideológicas, esse inusitado modo de vida produziu uma comunidade autônoma, com sujeitos autônomos e responsáveis uns pelos outros, que se tornaram lideranças sociais e políticas. No centro de sua história, experiências de sofrimento e rupturas relacionadas à religião, à fome, e à estrutura familiar patriarcal. O estudo do caso de Noiva do Cordeiro tem a intenção de analisar elementos subjetivos deste processo, verificando os indicativos e as implicações de tal fenômeno religioso e social, especialmente os limites e o fim de determinado modelo de religião. Os pressupostos teóricos deste estudo apontam para uma perspectiva transdisciplinar que compreende a teologia, a sociologia e a psicologia da religião e, nestes campos, as teorias feministas.Palavras-chave: Noiva do Cordeiro; modos de vida alternativos; fim da religião; liderança de mulheres; valores humanos

  14. CORPORATE STRATEGIES FOR GENERIC MEDICINES IN BRAZIL: A STUDY WITH THE SECTOR’S TEN LARGEST COMPANIEShttp://dx.doi.org/10.5585/riae.v10i1.1710

    Directory of Open Access Journals (Sweden)

    Silvia Antonio Sfair

    2011-06-01

    Full Text Available In Brazil, generic drugs are considered safe and effective and substantially cheaper than the so-called reference medicinal products. Due to this, generic drugs have become an important sector within the pharmaceutical market. However, topical studies are scarce and researchers focus on health professionals and direct sales. This article looks to expand on the understanding concerning the subject investigating the vision of those responsible for production, its relationship with physicians, government policies and delivery chain management in serving the consumer. To present this objective, in-depth interviews were conducted with ten executives occupying strategic positions in the pharmaceutical industry in general. The sample represents approximately 84% of generic drug sales in Brazil. The results have demonstrated that government performance plays an important role in the marketing of generic drugs to the population, while the drugstore and distributors were identified in this market as growth barriers, due to the practices used at point of sale. Doctors are considered the prime agent in popularizing the use of generic drugs in Brazil.

  15. Discurso e representação nas novelas Amor e Revolução e Sangue Bom http://dx.doi.org/10.15601/1983-7631/rt.v7n13p105-117

    Directory of Open Access Journals (Sweden)

    José Aparecido

    2015-02-01

    Full Text Available Resumo: Este artigo analisa a temática homoafetiva na representação e discurso dos personagens homossexuais das novelas Amor e Revolução, exibida pelo SBT, e Sangue Bom, exibida pela Rede Globo, à luz da perspectiva teórica da Análise do Discurso. Percebem-se inovações discursivas na teledramaturgia brasileira como integrante de um amplo processo na sociedade brasileira na luta por reconhecimento da identidade homossexual nos últimos anos. Os resultados demonstram não apenas uma mudança no padrão de representação dos personagens homossexuais, mas também a participação da ficção televisiva e sua apropriação dos espaços que partilham a luta dos movimentos que reclamam aceitação da identidade homossexual.Palavras-chave: telenovela; homoafetividade; análise de discurso.  Abstract: This article analyses homo-affection theme in the representation and discourse of homosexual personages in the novels Amor e Revolução, broadcasted on the SBT Television and Sangue Bom broadcasted on the Rede Globo,  in the light of the theoretical perspective of the Discourse Analysis. It is noticed the discussion innovations on the Brazilian novel as part of a broad process in the Brazilian society in its fight for homosexual identity recognition in the last years. The results demonstrate not only a change in the representation pattern of homosexual personages, but also the role of television fiction and its appropriation of places that share the movement fight which claim acceptance of the homosexual identity. Key words: Television novel; homo-affection; discourse analysis.

  16. Breves considerações acerca da atividade jurisdicional http://dx.doi.org/10.15601/1983-7631/rt.v2n3p41-53

    Directory of Open Access Journals (Sweden)

    Fernando Lage Tolentino

    2011-12-01

    Full Text Available O presente artigo busca analisar a concepção contemporânea da função jurisdicional. Para tanto, inicialmente foi analisada a evolução histórica da jurisdição, partindo dos meios de resolução de conflito da autotutela e da autocomposição, passando pela mediação e arbitragem romanas. Resta demonstrada a origem rudimentar da jurisdição no instituto da arbitragem pública obrigatória em Roma, bem como o desenvolvimento ocorrido ao longo da Idade Média e da Idade Moderna, sendo feita remissão expressa às concepções jurisdicionais no Estado Liberal e no Estado Social. A pesquisa é concluída com a demonstração da definição de jurisdição como função estatal de atuação dos conteúdos legais presentes no ordenamento jurídico, sob regulamentação da instituição constitucionalizada do processo, em consonância com o paradigma jurídico-constitucional do Estado Democrático de Direito.Palavras-chave: função jurisdicional; meios de resolução de conflito; estado democrático de direito

  17. Análise de estratégias de merchandising em telenovelas http://dx.doi.org/10.15601/1983-7631/rt.v7n13p157-167

    Directory of Open Access Journals (Sweden)

    Ana Clara Oliveira Santos Garner

    2015-02-01

    Full Text Available A televisão é um dos meios de comunicação e entretenimento mais utilizados pela sociedade. Dentre os programas de televisão mais assistidos no Brasil temos as telenovelas. Além de desenvolverem teledramaturgias de qualidade, também são utilizadas como o principal veículo de merchandising, no intuito de divulgar e estimular a compra de produtos e serviços. Este artigo faz uma análise do merchandising nas telenovelas da Rede Globo Sangue Bom e Amor à Vida. Seu objetivo foi identificar as principais ferramentas de merchandising usadas nas telenovelas, a fim de influenciar nos hábitos de consumo e comportamento dos telespectadores. A metodologia empregada foi a análise de conteúdo, por meio de categorias de análise.Palavras-chave: Telenovela; Rede Globo; Merchandising

  18. Secular trends: 10 and 20-year comparisons of sexual maturation among students. http://dx.doi.org/10.5007/1980-0037.2012v14n6p680

    Directory of Open Access Journals (Sweden)

    Rodrigo Mateus Farias

    2012-11-01

    Full Text Available The objective of this study was to verify the secular trends of sexual matu­ration of students between 11 and 15 years old, during a period of 10 and 20 years. The sample was composed by 1,002 students aged between 11 and 15 years; 536 boys (12.6±1.3 years old and 466 girls (12.5±1.2 years old who took part in the Ilhabela Mixed-Longitudinal Project on Growth, Development, and Physical Fitness. The students’ assessment period occurred in 1990/91 (initial, 2000/01 (10 years later, and 2009/10 (20 years later. Sexual maturation was analyzed according to the self-assessment method and age at menarche (month and year was collected retrospectively. The statistical analysis used was: one-way ANOVA, and Tukey’s post-hoc test. The level of significance was p<0.01. The onset of menarche in the initial analysis was at: 12.5±1.2 years old; in the 2000/01 group: 12.3±1.0 years old (Δ=-1.6%, and in the 2009/10 group: 12.2±1.0 years old (Δ=-2.4%. Although there was a tendency towards reduction in age at menarche along the periods in­vestigated, differences were not significant. There were significant differences only in genitals (G4, and pubic hair (P3 in boys after 10 and 20 years. In the same period, it did not occur any significant difference in maturational stages for girls. In conclusion, there was no secular trend of secondary sexual characteristics in boys (genital and pubic hair and girls (breast and pubic hair and in age at menarche over 10 and 20 years.

  19. A COMPANY'S INTERNAL POTENTIAL TO IMPLEMENT A STRATEGY TO ACQUIRE A COMPETITIVE ADVANTAGE: ACTION-RESEARCH WITHIN A MEXICAN COMPANYhttp://dx.doi.org/10.5585/riae.v9i2.1657

    Directory of Open Access Journals (Sweden)

    Víctor Gabriel Sánchez Trejo

    2010-11-01

    Full Text Available The small business in Mexico made an important contribution to the economic and social development of the country. Nevertheless, they present constant difficulties to reach a global and durable performance due to its specific characteristics. The generation of an internal development constitutes an alternative to compete with enterprises of the same size and with big companies in an external environment increasingly competitively and unstably.  This article presents an intervention-research in a medium company where the socioeconomic theory was applied and developed dynamical strategic capacities having a direct impact in the organizational and social performance of the company.

  20. NETFLIX: Sistemas de Recomendação Inteligentes http://dx.doi.org/10.15601/1983-7631/rt.v9n16p13-26

    Directory of Open Access Journals (Sweden)

    Daiana Sigiliano

    2016-06-01

    Full Text Available Resumo: A revolução tecnológica que emerge nas últimas duas décadas, tem possibilitado diversas opções de negócios através dos serviços que oferece armazenamento em cloud para consumidores finais. O caso do Netflix nos traz uma visão bem sólida da migração de um mercado de mídias físicas como o DVD e BluRay para os serviços de streaming de conteúdo. Revolucionando as estruturas de produção e principalmente de consumo de filmes, series, shows, documentários e outros, com base em algoritmos de recomendação esses modelos de negócio se ampliam cada vez mais. Este artigo propõe um panorama sobre essas amostras que envolvem os campos de big data, novas narrativas e engajamento em social media. Palavras Chave: Sistemas de Recomendação, Algoritmos, Mídia, Novas Narrativas, Social Mídia, Streaming.