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Sample records for jump tales knock

  1. A tale of quantum jumps

    International Nuclear Information System (INIS)

    Carmichael, H.J.

    2015-01-01

    This paper cannot provide anything like a complete overview of quantum optics in New Zealand. The scope over 40 years is far too broad and the number of players far too large. Nevertheless, the story of quantum jumps, from the days of the Old Quantum Theory up to the present, serves to highlight some small part of the New Zealand experience. It also offers an encounter with the oddities of light as a quantum mechanical 'something', oddities that the gallant proposers of technologies for the future aim to exploit. (author).

  2. A Knock at the Door. The Oryx Multicultural Folktale Series.

    Science.gov (United States)

    Shannon, George, Comp.

    This folktales collection includes 35 versions, representing countries and cultures from around the world, of the traditional tale in which a dangerous character knocks at the door and tries to trick the children into letting him inside. The stories are intended for use in homes, schools, and libraries by both children and adults who enjoy sharing…

  3. Phrygian Tales

    Directory of Open Access Journals (Sweden)

    J. B. Rives

    2010-11-01

    Full Text Available A survey of the ancient references to "Phrygian tales" reveals two characteristics: Euhemerizing accounts of the origin of the gods, and allegorical explanations of nature; the label may reflect the Phrygians' reputation as the oldest of nations.

  4. Jumping Dynamics

    DEFF Research Database (Denmark)

    Sannino, Francesco

    2013-01-01

    paradigm the physical scale and henceforth also the massive spectrum of the theory jump at the lower boundary of the conformal window. In particular we propose that a theory can suddenly jump from a Quantum Chromodynamics type spectrum, at the lower boundary of the conformal window, to a conformal one...... without particle interpretation. The jumping scenario, therefore, does not support a near-conformal dynamics of walking type. We will also discuss the impact of jumping dynamics on the construction of models of dynamical electroweak symmetry breaking....

  5. Statistical Engine Knock Control

    DEFF Research Database (Denmark)

    Stotsky, Alexander A.

    2008-01-01

    A new statistical concept of the knock control of a spark ignition automotive engine is proposed . The control aim is associated with the statistical hy pothesis test which compares the threshold value to the average value of the max imal amplitud e of the knock sensor signal at a given freq uency....... C ontrol algorithm which is used for minimization of the regulation error realizes a simple count-up-count-d own logic. A new ad aptation algorithm for the knock d etection threshold is also d eveloped . C onfi d ence interval method is used as the b asis for ad aptation. A simple statistical mod el...... which includ es generation of the amplitud e signals, a threshold value d etermination and a knock sound mod el is d eveloped for evaluation of the control concept....

  6. Extraordinary Tales

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 20; Issue 10. Extraordinary Tales: Parasites Hijacking the Minds of Hosts. Felix Bast. General Article Volume 20 Issue 10 October 2015 pp 893-902. Fulltext. Click here to view fulltext PDF. Permanent link:

  7. Knock-out reactions

    International Nuclear Information System (INIS)

    de Forest, T. Jr.

    1977-01-01

    It is pointed out that the primary motivation for performing high energy single nucleon knock-out reactions is based on the concept of quasi-elastic scattering. The validity of and corrections to the partial wave impulse approximation and kinematical invariance of knock-out reactions and tests of the reaction mechanism are treated. The effect of distortions on the momentum distribution in the effective momentum approximation for given parameters are plotted. 12 references

  8. Genome Editing in Rats Using TALE Nucleases.

    Science.gov (United States)

    Tesson, Laurent; Remy, Séverine; Ménoret, Séverine; Usal, Claire; Thinard, Reynald; Savignard, Chloé; De Cian, Anne; Giovannangeli, Carine; Concordet, Jean-Paul; Anegon, Ignacio

    2016-01-01

    The rat is an important animal model to understand gene function and model human diseases. Since recent years, the development of gene-specific nucleases has become important for generating new rat models of human diseases, to analyze the role of genes and to generate human antibodies. Transcription activator-like (TALE) nucleases efficiently create gene-specific knockout rats and lead to the possibility of gene targeting by homology-directed recombination (HDR) and generating knock-in rats. We describe a detailed protocol for generating knockout and knock-in rats via microinjection of TALE nucleases into fertilized eggs. This technology is an efficient, cost- and time-effective method for creating new rat models.

  9. Jumping together

    DEFF Research Database (Denmark)

    Lund, Ole; Ravn, Susanne; Christensen, Mette Krogh

    2014-01-01

    , in order to reach a deeper understanding of how practice facilitates learning. Results: We encircle the athletes’ interrelated learning processes by introducing the training environment of the national team and situations in which the athletes guide each other verbally or by jumping together. Discussion...

  10. Bowlegs and Knock-Knees

    Science.gov (United States)

    ... Español Text Size Email Print Share Bowlegs and Knock-Knees Page Content Article Body Toddlers’ legs often ... about two years old, then they’ll look knock-kneed until they are about six years of ...

  11. Supersonic Jump

    Science.gov (United States)

    Muller, Andreas

    2013-01-01

    On October 14,2012, Felix Baumgartner, an Austrian sky-diver, set some new world records for his discipline. Jumping from a height of about 39 km, he reached a top speed of 1342 km/h, becoming the first human being to break the sound barrier in free fall. In order to understand some essential physics aspects of this remarkable feat, we wonder why…

  12. TALE: a tale of genome editing.

    Science.gov (United States)

    Zhang, Mingjie; Wang, Feng; Li, Shifei; Wang, Yan; Bai, Yun; Xu, Xueqing

    2014-01-01

    Transcription activator-like effectors (TALEs), first identified in Xanthomonas bacteria, are naturally occurring or artificially designed proteins that modulate gene transcription. These proteins recognize and bind DNA sequences based on a variable numbers of tandem repeats. Each repeat is comprised of a set of ∼ 34 conserved amino acids; within this conserved domain, there are usually two amino acids that distinguish one TALE from another. Interestingly, TALEs have revealed a simple cipher for the one-to-one recognition of proteins for DNA bases. Synthetic TALEs have been used to successfully target genes in a variety of species, including humans. Depending on the type of functional domain that is fused to the TALE of interest, these proteins can have diverse biological effects. For example, after binding DNA, TALEs fused to transcriptional activation domains can function as robust transcription factors (TALE-TFs), while fused to restriction endonucleases (TALENs) can cut DNA. Targeted genome editing, in theory, is capable of modifying any endogenous gene sequence of interest; this can be performed in cells or organisms, and may be applied to clinical gene-based therapies in the future. With current technologies, highly accurate, specific, and reliable gene editing cannot be achieved. Thus, recognition and binding mechanisms governing TALE biology are currently hot research areas. In this review, we summarize the major advances in TALE technology over the past several years with a focus on the interaction between TALEs and DNA, TALE design and construction, potential applications for this technology, and unique characteristics that make TALEs superior to zinc finger endonucleases. Copyright © 2013 Elsevier Ltd. All rights reserved.

  13. Coordination in vertical jumping

    NARCIS (Netherlands)

    Bobbert, Maarten F.; van Ingen Schenau, Gerrit Jan

    1988-01-01

    The present study was designed to investigate for vertical jumping the relationships between muscle actions, movement pattern and jumping achievement. Ten skilled jumpers performed jumps with preparatory countermovement. Ground reaction forces and cinematographic data were recorded. In addition,

  14. Modern Baltic fairy tales in drama / Anneli Saro

    Index Scriptorium Estoniae

    Saro, Anneli, 1968-

    2009-01-01

    Jaan Tätte näidendist "Ristumine peateega, ehk, Muinasjutt kuldsest kalakesest" ("The highway crossing, or, The tale of a golden fish", tuntud ka pealkirjaga "Bungee jumping" ) ja Inga Ābele näidendist "Tumedad hirved" (The dark deer")

  15. Sibling fairy tales

    Directory of Open Access Journals (Sweden)

    Luisa Brunori

    2014-06-01

    Full Text Available The article offers a reflection on sibling relationships starting from fairy tales. Their archetypical meaning and educative value are particularly analyzed. A selection of fairy tales having sibling relationships as their central theme is discussed.

  16. Conditioning exercises in ski jumping: biomechanical relationship of squat jumps, imitation jumps, and hill jumps.

    Science.gov (United States)

    Lorenzetti, Silvio; Ammann, Fabian; Windmüller, Sabrina; Häberle, Ramona; Müller, Sören; Gross, Micah; Plüss, Michael; Plüss, Stefan; Schödler, Berni; Hübner, Klaus

    2017-11-22

    As hill jumps are very time-consuming, ski jumping athletes often perform various imitation jumps during training. The performed jumps should be similar to hill jumps, but a direct comparison of the kinetic and kinematic parameters has not been performed yet. Therefore, this study aimed to correlate 11 common parameters during hill jumps (Oberstdorf Germany), squat jumps (wearing indoor shoes), and various imitation jumps (rolling 4°, rolling flat, static; jumping equipment or indoor shoes) on a custom-built instrumented vehicle with a catch by the coach. During the performed jumps, force and video data of the take-off of 10 athletes were measured. The imitation and squat jumps were then ranked. The main difference between the hill jumps and the imitation and squat jumps is the higher maximal force loading rate during the hill jumps. Imitation jumps performed on a rolling platform, on flat ground were the most similar to hill jumps in terms of the force-time, and leg joint kinematic properties. Thus, non-hill jumps with a technical focus should be performed from a rolling platform with a flat inrun with normal indoor shoes or jumping equipment, and high normal force loading rates should be the main focus of imitation training.

  17. Richard Halliburton's Bearded Tales

    Science.gov (United States)

    Morris, Charles E., III

    2009-01-01

    Fusing the concept of "the beard" with the genre of the tall tale to theorize bearded tales deepens our understanding of closet eloquence, or rhetorical repertories of sexual passing in U.S. history. An examination of adventurer-writer-lecturer Richard Halliburton's sexual provenance and bestselling travel tale, "The Royal Road to Romance" (1925),…

  18. Telling tales.

    Science.gov (United States)

    Denning, Stephen

    2004-05-01

    A carefully chosen story can help the leader of an organization translate an abstract concept into a meaningful mandate for employees. The key is to know which narrative strategies are right for what circumstances. Knowledge management expert Stephen Denning explains that, for optimal effect, form should follow function. Challenging one professional storyteller's view that more is better, Denning points out that it's not always desirable (or practical) to launch into an epic that's jam-packed with complex characters, cleverly placed plot points, an intricate rising action, and a neatly resolved denouement. True, if listeners have time and interest, a narrative-savvy leader can use a vividly rendered tale to promote communication between management and staff, for instance, or even to foster collaboration--especially when the story is emotionally moving. However, if the aim is to motivate people to act when they might not be inclined to do so, it's best to take an approach that's light on detail. Otherwise, the particulars can bog listeners down and prevent them from focusing on the message. Drawing on his experiences at the World Bank and observations made elsewhere, the author provides several dos and don'ts for organizational storytellers, along with examples of narratives that get results. The sidebar "A Storytelling Catalog" presents seven distinct types of stories, the situations in which they should be told, and tips on how to tell them. Many of these aren't even stories in the "well-told" sense--they run the rhetorical gamut from one-liners to full-blown speeches--but they succeed because they're tailored to fit the situation. So even though it's common in business to favor the analytical over the anecdotal, leaders with the strength to push past some initial skepticism about the enterprise of storytelling will find that the creative effort pays off.

  19. Revisiting the TALE repeat.

    Science.gov (United States)

    Deng, Dong; Yan, Chuangye; Wu, Jianping; Pan, Xiaojing; Yan, Nieng

    2014-04-01

    Transcription activator-like (TAL) effectors specifically bind to double stranded (ds) DNA through a central domain of tandem repeats. Each TAL effector (TALE) repeat comprises 33-35 amino acids and recognizes one specific DNA base through a highly variable residue at a fixed position in the repeat. Structural studies have revealed the molecular basis of DNA recognition by TALE repeats. Examination of the overall structure reveals that the basic building block of TALE protein, namely a helical hairpin, is one-helix shifted from the previously defined TALE motif. Here we wish to suggest a structure-based re-demarcation of the TALE repeat which starts with the residues that bind to the DNA backbone phosphate and concludes with the base-recognition hyper-variable residue. This new numbering system is consistent with the α-solenoid superfamily to which TALE belongs, and reflects the structural integrity of TAL effectors. In addition, it confers integral number of TALE repeats that matches the number of bound DNA bases. We then present fifteen crystal structures of engineered dHax3 variants in complex with target DNA molecules, which elucidate the structural basis for the recognition of bases adenine (A) and guanine (G) by reported or uncharacterized TALE codes. Finally, we analyzed the sequence-structure correlation of the amino acid residues within a TALE repeat. The structural analyses reported here may advance the mechanistic understanding of TALE proteins and facilitate the design of TALEN with improved affinity and specificity.

  20. Risk, Jumps, and Diversification

    DEFF Research Database (Denmark)

    Bollerslev, Tim; Law, Tzuo Hann; Tauchen, George

    We test for price discontinuities, or jumps, in a panel of high-frequency intraday returns for forty large-cap stocks and an equiweighted index from these same stocks. Jumps are naturally classified into two types: common and idiosyncratic. Common jumps affect all stocks, albeit to varying degrees......, while idiosyncratic jumps are stock-specific. Despite the fact that each of the stocks has a of about unity with respect to the index, common jumps are virtually never detected in the individual stocks. This is truly puzzling, as an index can jump only if one or more of its components jump. To resolve...... this puzzle, we propose a new test for cojumps. Using this new test we find strong evidence for many modest-sized common jumps that simply pass through the standard jump detection statistic, while they appear highly significant in the cross section based on the new cojump identification scheme. Our results...

  1. Jumping in Arithmetic

    NARCIS (Netherlands)

    Visser, Albert

    In this paper we study a new relation between sentences: the jump relation. The idea of the jump relation is based on an analysis of Feferman's Theorem that the inconsistency of a theory U is interpretable over U. The jump relation is based on a converse of Feferman's Theorem: if a sentence is

  2. Jumping in Arithmetic

    NARCIS (Netherlands)

    Visser, Albert

    2014-01-01

    In this paper we study a new relation between sentences: the jump relation. The idea of the jump relation is based on an analysis of Feferman's Theorem that the inconsistency of a theory U is interpretable over U. The jump relation is based on a converse of Feferman's Theorem: if a sentence is

  3. New jump mechanisms for dumbbell and induced migration of point defects by molecular dynamics simulation

    International Nuclear Information System (INIS)

    Doan, N.V.; Pontikis, V.; Tenenbaum, A.

    1978-01-01

    The induced migration of the (100) - dumbbell is studied using the molecular dynamics simulation. Two new types of jumps are discovered for the dumbbell: first the jump takes place through an intermediate crowdion configuration (110), then the crowdion is converted into the dumbbell configuration with some other orientation. The threshold energy is found for different knocked-on directions. The dependence of the interstitial jump frequency on the incident electron energy is determined for copper. The induced interstitial migration shows a maximum value, but for an electron energy around 15 Kev. The effect of new jump mechanisms on the effective recombination volume is discussed

  4. Lost Opportunities: Rediscovering Fairy Tales

    Science.gov (United States)

    Wipf, Joan Brogan; Da Ros-Voseles, Denise

    2012-01-01

    The power of fairy tales resonates with children around the world. Fairy tales connect children on an emotional level that can help guide them through the complexities of everyday life. The tales provide stories rich in cultural heritage and the human condition, stories that not only delight children but also instruct. Because fairy tales state…

  5. Staggering but not knocked out

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2012-11-01

    Italy's PV market is staggering like a boxer almost knocked out. It has been hit hard by the country's deep economic recession. Conto Energia V has been yet another blow with cuts of up to 40 % in the solar feed-in tariffs. But the situation is not hopeless.

  6. The Science of Hard Knocks

    Science.gov (United States)

    Vance, Erik

    2007-01-01

    Head injuries in sports are nothing new, but in recent years, college athletes have reported a steady rise in concussions. Football players still get the most knocks to the head. Women have managed to keep up with, and often surpass, men in sports-related concussions in the last few years. In basketball, women reported 24 percent more concussions…

  7. Estimation of Jump Tails

    DEFF Research Database (Denmark)

    Bollerslev, Tim; Todorov, Victor

    We propose a new and flexible non-parametric framework for estimating the jump tails of Itô semimartingale processes. The approach is based on a relatively simple-to-implement set of estimating equations associated with the compensator for the jump measure, or its "intensity", that only utilizes...... the weak assumption of regular variation in the jump tails, along with in-fill asymptotic arguments for uniquely identifying the "large" jumps from the data. The estimation allows for very general dynamic dependencies in the jump tails, and does not restrict the continuous part of the process...... and the temporal variation in the stochastic volatility. On implementing the new estimation procedure with actual high-frequency data for the S&P 500 aggregate market portfolio, we find strong evidence for richer and more complex dynamic dependencies in the jump tails than hitherto entertained in the literature....

  8. Tales of Accreditation Woe.

    Science.gov (United States)

    Dickmeyer, Nathan

    2002-01-01

    Offers cautionary tales depicting how an "Enron mentality" infiltrated three universities and jeopardized their accreditation status. The schools were guilty, respectively, of bad bookkeeping, lack of strategy and stable leadership, and loss of academic integrity by selling degrees. (EV)

  9. What are quantum jumps?

    International Nuclear Information System (INIS)

    Cook, R.J.

    1988-01-01

    This paper answers the title question by giving an operational definition of quantum jumps based on measurement theory. This definition forms the basis of a theory of quantum jumps which leads to a number of testable predictions. Experiments are proposed to test the theory. The suggested experiments also test the quantum Zeno paradox, i.e., they test the proposition that frequent observation of a quantum system inhibits quantum jumps in that system. (orig.)

  10. Drop jumping. I. The influence of jumping technique on the biomechanics of jumping

    NARCIS (Netherlands)

    Bobbert, M F; Huijing, P A; van Ingen Schenau, G J

    In the literature, drop jumping is advocated as an effective exercise for athletes who prepare themselves for explosive activities. When executing drop jumps, different jumping techniques can be used. In this study, the influence of jumping technique on the biomechanics of jumping is investigated.

  11. Optimal Ski Jump

    Science.gov (United States)

    Rebilas, Krzysztof

    2013-01-01

    Consider a skier who goes down a takeoff ramp, attains a speed "V", and jumps, attempting to land as far as possible down the hill below (Fig. 1). At the moment of takeoff the angle between the skier's velocity and the horizontal is [alpha]. What is the optimal angle [alpha] that makes the jump the longest possible for the fixed magnitude of the…

  12. American Hyperbole: The Tall Tale.

    Science.gov (United States)

    Pavonetti, Linda M.; Combs, Christine M.

    1999-01-01

    Discusses the historic derivation and the format and characteristics of traditional tall tales, and modern adaptations of these stories. Describes a selection of tall tales for modern young adult readers; notes titles and authors of original tall tales and those with female heroes. Discusses the enduring appeal of traditional and modern tall…

  13. Psychoanalysis through fairy tale

    OpenAIRE

    Muhič, Aleksandra

    2012-01-01

    In my thesis I present the unconscious process of a man through a fairy tale analysis. All mankind represent a major part of the unconscious. The answers to the questions about the essential, existencialism, are obtained by this major quantity of the unconscious in every man. Through the symbolism of a fairy tale I present the way an individual has to walk to gain selfrealisation in life. Through fairytales a child in the process of his personality maturing step by step says goodb ye to...

  14. 16 tales of innovation

    DEFF Research Database (Denmark)

    16 Tales of Innovation are told by 16 leaders, who have completed the LAICS executive master program, a collaboration between Aarhus University and Copenhagen Business School. The book is based on their Master theses and illustrates how they have experimented with different innovation tools, models...

  15. Technology and Fairy Tales

    DEFF Research Database (Denmark)

    Nørgaard, Jørgen

    2005-01-01

    The Danish writer Hans Christian Andersen was born 200 years ago and lived in a time of enormous progress in technology and science. He was excited about this, but also worried about what they would do to humans and culture. This dilemma is expressed in some of Andersen's fairy tales, here...

  16. Jumping on water

    Science.gov (United States)

    Kim, Ho-Young

    2016-11-01

    Water striders can jump on water as high as they can jump on land. Quick jumps allow them to avoid sudden dangers such as predators' attacks, and therefore understanding how they make such a dramatic motion for survival can shed light on the ultimate level of semi-aquatic motility achievable through evolution. However, the mechanism of their vertical jumping from a water surface has eluded hydrodynamic explanations so far. By observing movements of water strider legs and theoretically analyzing their dynamic interactions with deforming liquid-air interface, we have recently found that different species of jumping striders always tune their leg rotation speed with a force just below that required to break the water surface to reach the maximum take-off velocity. Here, we start with discussing the fundamental theories of dynamics of floating and sinking of small objects. The theories then enable us to analyze forces acting on a water strider while it presses down the water surface to fully exploit the capillary force. We further introduce a 68-milligram at-scale robotic insect capable of jumping on water without splash, strikingly similar to the real strider, by utilizing the water surface just as a trampoline.

  17. The validity of knock-for-knock clauses in comparative perspective

    DEFF Research Database (Denmark)

    Cavaleri, Sylvie Cécile

    This article discusses the validity of so-called knock-for-knock clauses, by which parties to offshore oil and gas or maritime contracts agree that each of them will cover its own losses regardless of who caused them. The issue of validity of such clauses and of the liability exclusions they cont......This article discusses the validity of so-called knock-for-knock clauses, by which parties to offshore oil and gas or maritime contracts agree that each of them will cover its own losses regardless of who caused them. The issue of validity of such clauses and of the liability exclusions...... criteria used to promote or dismiss knock-for-knock clauses in case law and academic literature, the article reaches the conclusion that the question of whether knock-for-knock clauses should be held valid depends on whose interests are being considered, and that further research is warranted...

  18. The validity of knock-for-knock clauses in comparative perspective / Sylvie Cėcile Cavaleri

    Index Scriptorium Estoniae

    Cavaleri, Sylvie Cėcile

    2018-01-01

    Seoses Põhjamere nafta- ja gaasitootmisega sõlmitavatest lepingutest, kus kasutatakse nn "knock-for-knock" klausleid. Nende kohaselt katab iga lepingu osaline ise oma kahjud, sõltumata kahjude põhjustajast

  19. Relationships Between Countermovement Jump Ground Reaction Forces and Jump Height, Reactive Strength Index, and Jump Time.

    Science.gov (United States)

    Barker, Leland A; Harry, John R; Mercer, John A

    2018-01-01

    Barker, LA, Harry, JR, and Mercer, JA. Relationships between countermovement jump ground reaction forces and jump height, reactive strength index, and jump time. J Strength Cond Res 32(1): 248-254, 2018-The purpose of this study was to determine the relationship between ground reaction force (GRF) variables to jump height, jump time, and the reactive strength index (RSI). Twenty-six, Division-I, male, soccer players performed 3 maximum effort countermovement jumps (CMJs) on a dual-force platform system that measured 3-dimensional kinetic data. The trial producing peak jump height was used for analysis. Vertical GRF (Fz) variables were divided into unloading, eccentric, amortization, and concentric phases and correlated with jump height, RSI (RSI = jump height/jump time), and jump time (from start to takeoff). Significant correlations were observed between jump height and RSI, concentric kinetic energy, peak power, concentric work, and concentric displacement. Significant correlations were observed between RSI and jump time, peak power, unload Fz, eccentric work, eccentric rate of force development (RFD), amortization Fz, amortization time, second Fz peak, average concentric Fz, and concentric displacement. Significant correlations were observed between jump time and unload Fz, eccentric work, eccentric RFD, amortization Fz, amortization time, average concentric Fz, and concentric work. In conclusion, jump height correlated with variables derived from the concentric phase only (work, power, and displacement), whereas Fz variables from the unloading, eccentric, amortization, and concentric phases correlated highly with RSI and jump time. These observations demonstrate the importance of countermovement Fz characteristics for time-sensitive CMJ performance measures. Researchers and practitioners should include RSI and jump time with jump height to improve their assessment of jump performance.

  20. Why is countermovement jump height greater than squat jump height?

    NARCIS (Netherlands)

    Bobbert, Maarten F.; Gerritsen, Karin G M; Litjens, Maria C A; Van Soest, Arthur J.

    1996-01-01

    In the literature, it is well established that subjects are able to jump higher in a countermovement jump (CMJ) than in a squat jump (SJ). The purpose of this study was to estimate the relative contribution of the time available for force development and the storage and reutilization of elastic

  1. Drop Jumping as a Training Method for Jumping Ability

    NARCIS (Netherlands)

    Bobbert, Maarten F.

    1990-01-01

    Vertical jumping ability is of importance for good performance in sports such as basketball and volleyball. Coaches are in need of exercises that consume only little time and still help to improve their players’ jumping ability, without involving a high risk of injury. Drop jumping is assumed to

  2. Jump into Action

    Science.gov (United States)

    Ball, Stephen; Cohen, Ann; Meyer, Margaret

    2012-01-01

    Jump Into Action (JIA) is a school-based team-taught program to help fifth-grade students make healthy food choices and be more active. The JIA team (physical education teacher, classroom teacher, school nurse, and parent) work together to provide a supportive environment as students set goals to improve food choices and increase activity.…

  3. Egg Bungee Jump!

    Science.gov (United States)

    Fitzgerald, Mike; Brand, Lance

    2004-01-01

    In this article, the authors present an egg bungee jumping activity. This activity introduces students to ways that engineers might apply calculations of failure to meet a challenge. Students are required to use common, everyday materials such as rubber bands, string, plastic bags, and eggs. They will apply technological problem solving, material…

  4. SARS – virus jumps species

    Indian Academy of Sciences (India)

    SARS – virus jumps species. Coronavirus reshuffles genes; Rotteir et al, Rotterdam showed the virus to jump from cats to mouse cells after single gene mutation ? Human disease due to virus jumping from wild or domestic animals; Present favourite animal - the cat; - edible or domestic.

  5. Tall Tales of North America.

    Science.gov (United States)

    Fresno City Unified School District, CA.

    Designed for use in junior high school language arts classes, this learning activity packet introduces students to North American folklore. Selected readings cover Indian tales, real folk heroes (Davy Crockett and John Henry), imaginary folk heroes (Paul Bunyan and Pecos Bill), Black folk stories (Brer Rabbit), and tales of Washington Irving. Each…

  6. Genetic Contributors to Intergenerational CAG Repeat Instability in Huntington's Disease Knock-In Mice.

    Science.gov (United States)

    Neto, João Luís; Lee, Jong-Min; Afridi, Ali; Gillis, Tammy; Guide, Jolene R; Dempsey, Stephani; Lager, Brenda; Alonso, Isabel; Wheeler, Vanessa C; Pinto, Ricardo Mouro

    2017-02-01

    Huntington's disease (HD) is a neurodegenerative disorder caused by the expansion of a CAG trinucleotide repeat in exon 1 of the HTT gene. Longer repeat sizes are associated with increased disease penetrance and earlier ages of onset. Intergenerationally unstable transmissions are common in HD families, partly underlying the genetic anticipation seen in this disorder. HD CAG knock-in mouse models also exhibit a propensity for intergenerational repeat size changes. In this work, we examine intergenerational instability of the CAG repeat in over 20,000 transmissions in the largest HD knock-in mouse model breeding datasets reported to date. We confirmed previous observations that parental sex drives the relative ratio of expansions and contractions. The large datasets further allowed us to distinguish effects of paternal CAG repeat length on the magnitude and frequency of expansions and contractions, as well as the identification of large repeat size jumps in the knock-in models. Distinct degrees of intergenerational instability were observed between knock-in mice of six background strains, indicating the occurrence of trans-acting genetic modifiers. We also found that lines harboring a neomycin resistance cassette upstream of Htt showed reduced expansion frequency, indicative of a contributing role for sequences in cis, with the expanded repeat as modifiers of intergenerational instability. These results provide a basis for further understanding of the mechanisms underlying intergenerational repeat instability. Copyright © 2017 by the Genetics Society of America.

  7. Accuracy of Jump-Mat Systems for Measuring Jump Height.

    Science.gov (United States)

    Pueo, Basilio; Lipinska, Patrycja; Jiménez-Olmedo, José M; Zmijewski, Piotr; Hopkins, Will G

    2017-08-01

    Vertical-jump tests are commonly used to evaluate lower-limb power of athletes and nonathletes. Several types of equipment are available for this purpose. To compare the error of measurement of 2 jump-mat systems (Chronojump-Boscosystem and Globus Ergo Tester) with that of a motion-capture system as a criterion and to determine the modifying effect of foot length on jump height. Thirty-one young adult men alternated 4 countermovement jumps with 4 squat jumps. Mean jump height and standard deviations representing technical error of measurement arising from each device and variability arising from the subjects themselves were estimated with a novel mixed model and evaluated via standardization and magnitude-based inference. The jump-mat systems produced nearly identical measures of jump height (differences in means and in technical errors of measurement ≤1 mm). Countermovement and squat-jump height were both 13.6 cm higher with motion capture (90% confidence limits ±0.3 cm), but this very large difference was reduced to small unclear differences when adjusted to a foot length of zero. Variability in countermovement and squat-jump height arising from the subjects was small (1.1 and 1.5 cm, respectively, 90% confidence limits ±0.3 cm); technical error of motion capture was similar in magnitude (1.7 and 1.6 cm, ±0.3 and ±0.4 cm), and that of the jump mats was similar or smaller (1.2 and 0.3 cm, ±0.5 and ±0.9 cm). The jump-mat systems provide trustworthy measurements for monitoring changes in jump height. Foot length can explain the substantially higher jump height observed with motion capture.

  8. A multicolor panel of TALE-KRAB based transcriptional repressor vectors enabling knockdown of multiple gene targets.

    Science.gov (United States)

    Zhang, Zhonghui; Wu, Elise; Qian, Zhijian; Wu, Wen-Shu

    2014-12-05

    Stable and efficient knockdown of multiple gene targets is highly desirable for dissection of molecular pathways. Because it allows sequence-specific DNA binding, transcription activator-like effector (TALE) offers a new genetic perturbation technique that allows for gene-specific repression. Here, we constructed a multicolor lentiviral TALE-Kruppel-associated box (KRAB) expression vector platform that enables knockdown of multiple gene targets. This platform is fully compatible with the Golden Gate TALEN and TAL Effector Kit 2.0, a widely used and efficient method for TALE assembly. We showed that this multicolor TALE-KRAB vector system when combined together with bone marrow transplantation could quickly knock down c-kit and PU.1 genes in hematopoietic stem and progenitor cells of recipient mice. Furthermore, our data demonstrated that this platform simultaneously knocked down both c-Kit and PU.1 genes in the same primary cell populations. Together, our results suggest that this multicolor TALE-KRAB vector platform is a promising and versatile tool for knockdown of multiple gene targets and could greatly facilitate dissection of molecular pathways.

  9. Deconstructing Gender in Revised Feminist Fairy Tales

    Science.gov (United States)

    Mcandrew, Linda

    2013-01-01

    Power relationships are a central premise in children's literature, especially traditional fairy tales and modern feminist fairy tales. This is seen in many fairy tales where the main female character is in some distress, her Prince Charming rescues her, and they live happily ever after. Modern feminist fairy tales are understood to be a forum…

  10. Optimal Ski Jump

    Science.gov (United States)

    Rebilas, Krzysztof

    2013-02-01

    Consider a skier who goes down a takeoff ramp, attains a speed V, and jumps, attempting to land as far as possible down the hill below (Fig. 1). At the moment of takeoff the angle between the skier's velocity and the horizontal is α. What is the optimal angle α that makes the jump the longest possible for the fixed magnitude of the velocity V? Of course, in practice, this is a very sophisticated problem; the skier's range depends on a variety of complex factors in addition to V and α. However, if we ignore these and assume the jumper is in free fall between the takeoff ramp and the landing point below, the problem becomes an exercise in kinematics that is suitable for introductory-level students. The solution is presented here.

  11. Jumping hoops on water

    Science.gov (United States)

    Yang, Eunjin; Kim, Ho-Young

    2015-11-01

    Small aquatic arthropods, such as water striders and fishing spiders, are able to jump off water to a height several times their body length. Inspired by the unique biological motility on water, we study a simple model using a flexible hoop to provide fundamental understanding and a mimicking principle of small jumpers on water. Behavior of a hoop on water, which is coated with superhydrophobic particles and initially bent into an ellipse from an equilibrium circular shape, is visualized with a high speed camera upon launching it into air by releasing its initial elastic strain energy. We observe that jumping of our hoops is dominated by the dynamic pressure of water rather than surface tension, and thus it corresponds to the dynamic condition experienced by fishing spiders. We calculate the reaction forces provided by water adopting the unsteady Bernoulli equation as well as the momentum loss into liquid inertia and viscous friction. Our analysis allows us to predict the jumping efficiency of the hoop on water in comparison to that on ground, and to discuss the evolutionary pressure rendering fishing spiders select such dynamic behavior.

  12. Undular Hydraulic Jump

    Directory of Open Access Journals (Sweden)

    Oscar Castro-Orgaz

    2015-04-01

    Full Text Available The transition from subcritical to supercritical flow when the inflow Froude number Fo is close to unity appears in the form of steady state waves called undular hydraulic jump. The characterization of the undular hydraulic jump is complex due to the existence of a non-hydrostatic pressure distribution that invalidates the gradually-varied flow theory, and supercritical shock waves. The objective of this work is to present a mathematical model for the undular hydraulic jump obtained from an approximate integration of the Reynolds equations for turbulent flow assuming that the Reynolds number R is high. Simple analytical solutions are presented to reveal the physics of the theory, and a numerical model is used to integrate the complete equations. The limit of application of the theory is discussed using a wave breaking condition for the inception of a surface roller. The validity of the mathematical predictions is critically assessed using physical data, thereby revealing aspects on which more research is needed

  13. A RANS knock model to predict the statistical occurrence of engine knock

    International Nuclear Information System (INIS)

    D'Adamo, Alessandro; Breda, Sebastiano; Fontanesi, Stefano; Irimescu, Adrian; Merola, Simona Silvia; Tornatore, Cinzia

    2017-01-01

    Highlights: • Development of a new RANS model for SI engine knock probability. • Turbulence-derived transport equations for variances of mixture fraction and enthalpy. • Gasoline autoignition delay times calculated from detailed chemical kinetics. • Knock probability validated against experiments on optically accessible GDI unit. • PDF-based knock model accounting for the random nature of SI engine knock in RANS simulations. - Abstract: In the recent past engine knock emerged as one of the main limiting aspects for the achievement of higher efficiency targets in modern spark-ignition (SI) engines. To attain these requirements, engine operating points must be moved as close as possible to the onset of abnormal combustions, although the turbulent nature of flow field and SI combustion leads to possibly ample fluctuations between consecutive engine cycles. This forces engine designers to distance the target condition from its theoretical optimum in order to prevent abnormal combustion, which can potentially damage engine components because of few individual heavy-knocking cycles. A statistically based RANS knock model is presented in this study, whose aim is the prediction not only of the ensemble average knock occurrence, poorly meaningful in such a stochastic event, but also of a knock probability. The model is based on look-up tables of autoignition times from detailed chemistry, coupled with transport equations for the variance of mixture fraction and enthalpy. The transported perturbations around the ensemble average value are based on variable gradients and on a local turbulent time scale. A multi-variate cell-based Gaussian-PDF model is proposed for the unburnt mixture, resulting in a statistical distribution for the in-cell reaction rate. An average knock precursor and its variance are independently calculated and transported; this results in the prediction of an earliest knock probability preceding the ensemble average knock onset, as confirmed by

  14. Tales of Tourism

    DEFF Research Database (Denmark)

    Smed, Karina Madsen

    2011-01-01

    " and the "others". The author discusses to which extent tourism discourse is global as the reception of it has been different depending on the context. Moreover, she reflects on the impact upon this global narrative that the new economic world order will have. The new and emergent economies lead to a flow......Tales of Tourism - Global Changes and tourism discourse by Karina Smed presents us with what has been the dominant discourse of tourism, i.e. a discourse which has had its roots in the West's economic and cultural hegemony and the problem of the formation of identity from the dichotomy "self...... of tourists in the opposite direction: from China, India and Russia to western countries and worldwide and this will probably change the concept of tourism and our idea of identities....

  15. 'Knock, and it shall be opened': knocking out and knocking in to reveal mechanisms of disease and novel therapies.

    Science.gov (United States)

    Hacking, Douglas F

    2008-12-01

    Recent significant advances in molecular biology have generated genetically modified bacteria, yeast, nematodes, fruit flies, and fish. However, it is the genetic modification of mammalian model organisms, particularly the mouse, that has the greatest potential to shed light on human development, physiology and pathology in ways that have significant implications for neonatal and paediatric clinical practice. Here, we review some of the techniques for knocking out (inactivating), mutating and knocking in (inserting) selected genes that are important to neonatology and show how this research will lead both to a better understanding of disease and to novel therapies for infants and children.

  16. BPS Jumping Loci are Automorphic

    Science.gov (United States)

    Kachru, Shamit; Tripathy, Arnav

    2018-06-01

    We show that BPS jumping loci-loci in the moduli space of string compactifications where the number of BPS states jumps in an upper semi-continuous manner—naturally appear as Fourier coefficients of (vector space-valued) automorphic forms. For the case of T 2 compactification, the jumping loci are governed by a modular form studied by Hirzebruch and Zagier, while the jumping loci in K3 compactification appear in a story developed by Oda and Kudla-Millson in arithmetic geometry. We also comment on some curious related automorphy in the physics of black hole attractors and flux vacua.

  17. Proton knock-out in Hall A

    International Nuclear Information System (INIS)

    Jager, K. de

    2003-01-01

    Proton knock-out is studied in a broad program in Hall A at Jefferson Lab. The first experiment performed in Hall A studied the 16 O(e,e'p) reaction. Since then proton knock-out experiments have studied a variety of aspects of that reaction, from single-nucleon properties to its mechanism, such as final-state interactions and two-body currents, in nuclei from 2 H to 16 O. In this review the accomplishments of this program will be summarized and an outlook given of expected future results. (orig.)

  18. Exploring Lightning Jump Characteristics

    Science.gov (United States)

    Chronis, Themis; Carey, Larry D.; Schultz, Christopher J.; Schultz, Elise; Calhoun, Kristin; Goodman, Steven J.

    2014-01-01

    This study is concerned with the characteristics of storms exhibiting an abrupt temporal increase in the total lightning flash rate (i.e., lightning jump, LJ). An automated storm tracking method is used to identify storm "clusters" and total lightning activity from three different lightning detection systems over Oklahoma, northern Alabama and Washington, D.C. On average and for different employed thresholds, the clusters that encompass at least one LJ (LJ1) last longer, relate to higher Maximum Expected Size of Hail, Vertical Integrated Liquid and lightning flash rates (area-normalized) than the clusters that did not exhibit any LJ (LJ0). The respective mean values for LJ1 (LJ0) clusters are 80 min (35 min), 14 mm (8 mm), 25 kg per square meter (18 kg per square meter) and 0.05 flash per min per square kilometer (0.01 flash per min per square kilometer). Furthermore, the LJ1 clusters are also characterized by slower decaying autocorrelation functions, a result that implies a less "random" behavior in the temporal flash rate evolution. In addition, the temporal occurrence of the last LJ provides an estimate of the time remaining to the storm's dissipation. Depending of the LJ strength (i.e., varying thresholds), these values typically range between 20-60 min, with stronger jumps indicating more time until storm decay. This study's results support the hypothesis that the LJ is a proxy for the storm's kinematic and microphysical state rather than a coincidental value.

  19. Jump conditions in transonic equilibria

    International Nuclear Information System (INIS)

    Guazzotto, L.; Betti, R.; Jardin, S. C.

    2013-01-01

    In the present paper, the numerical calculation of transonic equilibria, first introduced with the FLOW code in Guazzotto et al.[Phys. Plasmas 11, 604 (2004)], is critically reviewed. In particular, the necessity and effect of imposing explicit jump conditions at the transonic discontinuity are investigated. It is found that “standard” (low-β, large aspect ratio) transonic equilibria satisfy the correct jump condition with very good approximation even if the jump condition is not explicitly imposed. On the other hand, it is also found that high-β, low aspect ratio equilibria require the correct jump condition to be explicitly imposed. Various numerical approaches are described to modify FLOW to include the jump condition. It is proved that the new methods converge to the correct solution even in extreme cases of very large β, while they agree with the results obtained with the old implementation of FLOW in lower-β equilibria.

  20. Mechanics of jumping on water

    Science.gov (United States)

    Kim, Ho-Young; Amauger, Juliette; Jeong, Han-Bi; Lee, Duck-Gyu; Yang, Eunjin; Jablonski, Piotr G.

    2017-10-01

    Some species of semiaquatic arthropods including water striders and springtails can jump from the water surface to avoid sudden dangers like predator attacks. It was reported recently that the jump of medium-sized water striders is a result of surface-tension-dominated interaction of thin cylindrical legs and water, with the leg movement speed nearly optimized to achieve the maximum takeoff velocity. Here we describe the mathematical theories to analyze this exquisite feat of nature by combining the review of existing models for floating and jumping and the introduction of the hitherto neglected capillary forces at the cylinder tips. The theoretically predicted dependence of body height on time is shown to match the observations of the jumps of the water striders and springtails regardless of the length of locomotory appendages. The theoretical framework can be used to understand the design principle of small jumping animals living on water and to develop biomimetic locomotion technology in semiaquatic environments.

  1. Knock out for subthreshold pion production

    International Nuclear Information System (INIS)

    Guet, C.; Prakash, M.

    1984-05-01

    The contribution of nucleon-nucleon-single collisions to subthreshold pion production in hadron-nucleus and nucleus-nucleus collisions, Esub(Lab) < 300 A MeV is investigated within a knock-out type model. This contribution might be important for energies higher than about 150 MeV/nucleon but decrease strongly with decreasing beam energy

  2. Parallel knock-out schemes in networks

    NARCIS (Netherlands)

    Broersma, H.J.; Fomin, F.V.; Woeginger, G.J.

    2004-01-01

    We consider parallel knock-out schemes, a procedure on graphs introduced by Lampert and Slater in 1997 in which each vertex eliminates exactly one of its neighbors in each round. We are considering cases in which after a finite number of rounds, where the minimimum number is called the parallel

  3. Knocking in an Internal-combustion Engine

    Science.gov (United States)

    Sokolik, A; Voinov, A

    1940-01-01

    The question remains open of the relation between the phenomena of knocking in the engine and the explosion wave. The solution of this problem is the object of this paper. The tests were conducted on an aircraft engine with a pyrex glass window in the cylinder head. Photographs were then taken of various combinations of fuels and conditions.

  4. The interactions between IC engine thermodynamics and knock

    International Nuclear Information System (INIS)

    Caton, Jerald A.

    2017-01-01

    Highlights: • Importance of engine thermodynamics regarding knock was quantified. • Effects of compression ratio, engine speed and EGR on knock was reported. • Retarding combustion to avoid knock resulted in decreases of efficiency. - Abstract: The development of high efficiency spark-ignition internal combustion engines is often constrained by the occurrence of knock. Knock may result in engine damage, lower performance, and lower efficiency. The options for preventing knock often involve lower compression ratios, lower boost, retarded spark timing, and other design choices that are detrimental to engine performance and efficiency. Since knock is largely a function of the thermodynamic state of the unburned zone, the occurrence of knock is expected to be a strong function of the engine thermodynamics. The purpose of the current work is to couple a simple knock model with a comprehensive engine cycle simulation to determine the interactions between the engine thermodynamics and knock. This work has explored the effects of engine parameters such as compression ratio (4–12), engine speed (500–2500 rpm), inlet pressure (50–100 kPa), exhaust gas recirculation (0–25%), combustion duration and heat transfer on knock. In each case, the occurrence of knock is connected to the cylinder pressures and the gas temperatures of the unburned zone. For example for a compression ratio of 12, to avoid knock the brake thermal efficiency decreased from 36.5% to 34% due to retarding the combustion.

  5. Thersites: a `jumping' Trojan?

    Science.gov (United States)

    Tsiganis, K.; Dvorak, R.; Pilat-Lohinger, E.

    2000-02-01

    In this paper, we examine the dynamical evolution of the asteroid (1868) Thersites, a member of the Trojan belt. Thersites is librating around the Lagrangian point L_4, following, however, a chaotic orbit. The equations of motion for Thersites as well as for a distribution of neighboring initial conditions are integrated numerically for 50 million years in the Outer Solar System model (OSS), which consists of the Sun and the four giant planets. Our results indicate that the probability that this asteroid will eventually escape from the Trojan swarm is rather high. In fact, 20% from our initial distribution escaped within the integration time. Many of the remaining ones also show characteristic `jumps' in the orbital elements, especially the inclination. Secular resonances involving the nodes of the outer planets are found to be responsible for this chaotic behavior. The width of libration and eccentricity values that lead to grossly unstable orbits are calculated and compared with previously known results on the stability of the Trojans. Finally, a very interesting behavior has been observed for one of the escaping asteroids as he `jumped' from L_4 to L_5 where he remained performing a highly inclined libration for ~ 2 Myrs before escaping from the Trojan swarm. According to Homer, Thersites was not only the ugliest of all Greeks that took part in the Trojan war, but also had the most intolerable personality. His nasty habit of making fun of everybody cost him his life, as the last person for whom he spoke ironically about was Achilles, the mightiest warrior of all Greeks, who killed Thersites with just one punch!

  6. Contest in Nanai Shamanic Tales

    Directory of Open Access Journals (Sweden)

    Tatiana Diomidovna Bulgakova

    2015-06-01

    Full Text Available The tale motif of the shamanic tale competition is examined with due regard for the interpretation given by the Nanai storyteller-shamans from the standpoint of their personal spiritual experience. In shamanic practice it is not the personal ability (skill or physical power that provides a challenger victory in conflict, but obtaining spirits-helpers more powerful than those of his or her rival. The predominate role of these fantastic personages/helpers in tales that represent invisible spirit helpers perform real shamanic praxis, explains the loser’s unconditional submission and readiness to sacrifice their freedom or life to the winner. It also clarifies the motivation of the initiators of these contests and games: by means of gathering a great number of competitors, such shamans solve their personal spiritual problems, such as the need to overcome their adversaries or find allies in the struggle against their opponents.

  7. The TA and TALE Experiments

    International Nuclear Information System (INIS)

    Thomson, Gordon

    2006-01-01

    The TA/TALE experiment is under construction, and is being deployed in Millard County, Utah. It will consist of a suite of detectors covering four orders of magnitude in energy, from 10 16.5 to 10 20.5 eV, and will observe cosmic ray showers with fluorescence detectors and arrays of scintillation counters. Events will be seen by multiple detectors and cross calibration of detectors' energy scales will be possible. TA/TALE will observe all three features of the spectrum of ultrahigh energy cosmic rays, observe the galactic/extragalactic transition, study the cosmology of cosmic ray sources, and perform anisotropy studies with unprecedented accuracy

  8. Jump probabilities in the non-Markovian quantum jump method

    International Nuclear Information System (INIS)

    Haerkoenen, Kari

    2010-01-01

    The dynamics of a non-Markovian open quantum system described by a general time-local master equation is studied. The propagation of the density operator is constructed in terms of two processes: (i) deterministic evolution and (ii) evolution of a probability density functional in the projective Hilbert space. The analysis provides a derivation for the jump probabilities used in the recently developed non-Markovian quantum jump (NMQJ) method (Piilo et al 2008 Phys. Rev. Lett. 100 180402).

  9. Choice of jumping strategy in two standard jumps, squat and countermovement jump--effect of training background or inherited preference?

    DEFF Research Database (Denmark)

    Ravn, Susanne; Voigt, M; Simonsen, Erik Bruun

    1999-01-01

    . The jumps were recorded on highspeed film (500 Hz) combined with registration of ground reaction forces, and net joint moments were calculated by inverse dynamics. The purpose was to investigate the choice of strategy in two standard jumps, squat jump and countermovement jump. The volleyball jump...... was performed with a sequential strategy and the ballet jump was performed with a simultaneous strategy. In the two standard jumps, the choice of strategy was individual and not related to training background. This was additionally confirmed in a test of seven ballet dancers and seven volleyball players....

  10. Ladrillo and Tales of Juan Bobo: Puerto Rican Folk Tales.

    Science.gov (United States)

    Matos, Reinaldo; Matos, Ana

    These two illustrated elementary readers contain the Spanish and English versions of the Puerto Rican folk tales, "Ladrillo" and "Cuentos de Juan Bobo." They are part of a series of reading materials for elementary-level migrant children. These materials are intended to help the child relate to his culture, develop interest in…

  11. HANSEL AND GRETEL: A TALE OF TERROR.

    Science.gov (United States)

    White, Robert S

    2015-10-01

    In the analysis of a woman with multiple childhood traumas, the fairy tale "Hansel and Gretel" figured prominently. The author discusses the use of the fairy tale in this case at various levels. He suggests an interplay between a national myth, the fairy tale, and a personal myth-the patient's psychodynamics. The fairy tale can be used to illuminate personal meanings derived from it. In the experience of childhood trauma, the repeated reading of a fairy tale can help organize and defend against terrifying anxiety. © 2015 The Psychoanalytic Quarterly, Inc.

  12. Hydraulic jumps in a channel

    DEFF Research Database (Denmark)

    Bonn, D.; Andersen, Anders Peter; Bohr, Tomas

    2009-01-01

    We present a study of hydraulic jumps with flow predominantly in one direction, created either by confining the flow to a narrow channel with parallel walls or by providing an inflow in the form of a narrow sheet. In the channel flow, we find a linear height profile upstream of the jump as expected......'s mixing-length theory with a mixing length that is proportional to the height of the fluid layer. Using averaged boundary-layer equations, taking into account the friction with the channel walls and the eddy viscosity, the flow both upstream and downstream of the jump can be understood. For the downstream...... subcritical flow, we assume that the critical height is attained close to the channel outlet. We use mass and momentum conservation to determine the position of the jump and obtain an estimate which is in rough agreement with our experiment. We show that the averaging method with a varying velocity profile...

  13. Birth of a hydraulic jump

    Science.gov (United States)

    Duchesne, Alexis; Bohr, Tomas; Andersen, Anders

    2017-11-01

    The hydraulic jump, i.e., the sharp transition between a supercritical and a subcritical free-surface flow, has been extensively studied in the past centuries. However, ever since Leonardo da Vinci asked it for the first time, an important question has been left unanswered: How does a hydraulic jump form? We present an experimental and theoretical study of the formation of stationary hydraulic jumps in centimeter wide channels. Two starting situations are considered: The channel is, respectively, empty or filled with liquid, the liquid level being fixed by the wetting properties and the boundary conditions. We then change the flow-rate abruptly from zero to a constant value. In an empty channel, we observe the formation of a stationary hydraulic jump in a two-stage process: First, the channel fills by the advancing liquid front, which undergoes a transition from supercritical to subcritical at some position in the channel. Later the influence of the downstream boundary conditions makes the jump move slowly upstream to its final position. In the pre-filled channel, the hydraulic jump forms at the injector edge and then moves downstream to its final position.

  14. Creative Thinking with Fairy Tales.

    Science.gov (United States)

    Flack, Jerry

    2001-01-01

    This article discusses how creative thinking can be encouraged in students through such classic tools as brainstorming and the productive thinking elements of fluency, flexibility, originality, and elaboration. It describes how fairy tales can be used to foster these thinking skills and suggests classroom activities. (Contains two references.) (CR)

  15. Learning through a Winter's Tale

    Science.gov (United States)

    Vidotto, Kristie

    2010-01-01

    In this article, the author shares her experience during the final semester of Year 11 Theatre Studies when she performed a monologue about Hermione from "The Winter's Tale". This experience was extremely significant to her because it nearly made her lose faith in one of the most important parts of her life, drama. She believes this…

  16. A Tale of Four Electrons

    Science.gov (United States)

    Burgmayer, Paul

    2011-01-01

    "A Tale of Four Electrons" is a creative writing assignment used with 10th-grade Honors Chemistry students. The project helps students consolidate their learning about bonding--an important unifying theme in chemistry--and answers questions such as (1) How are ionic, metallic, and covalent bonds related? (2) How do variations in electron…

  17. [A tale of two encounters].

    Science.gov (United States)

    Chanel, Marie-Paule

    The moving testimony of a patient shows the impact which a successful encounter can have. Beyond the positive clinical consequences, her rediscovered motivation and pleasure are the essential drivers which have guided her along the pathway of reconstruction. A tale of two encounters which have marked her life course. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  18. Variation in free jumping technique within and among horses with little experience in show jumping

    NARCIS (Netherlands)

    Santamaria, S.; Bobbert, M.F.; Back, W.; Barneveld, A.; van Weeren, P.R.

    2004-01-01

    Objective - To quantify variation in the jumping technique within and among young horses with little jumping experience, establish relationships between kinetic and kinematic variables, and identify a limited set of variables characteristic for detecting differences in jumping performance among

  19. Timeless Approach to Quantum Jumps

    Directory of Open Access Journals (Sweden)

    Ignazio Licata

    2015-10-01

    Full Text Available According to the usual quantum description, the time evolution of the quantum state is continuous and deterministic except when a discontinuous and indeterministic collapse of state vector occurs. The collapse has been a central topic since the origin of the theory, although there are remarkable theoretical proposals to understand its nature, such as the Ghirardi–Rimini–Weber. Another possibility could be the assimilation of collapse with the now experimentally well established phenomenon of quantum jump, postulated by Bohr already in 1913. The challenge of nonlocality offers an opportunity to reconsider the quantum jump as a fundamental element of the logic of the physical world, rather than a subsidiary accident. We propose here a simple preliminary model that considers quantum jumps as processes of entry to and exit from the usual temporal domain to a timeless vacuum, without contradicting the quantum relativistic formalism, and we present some potential connections with particle physics. Quanta 2015; 4: 10–26.

  20. Quantum jumps on Anderson attractors

    Science.gov (United States)

    Yusipov, I. I.; Laptyeva, T. V.; Ivanchenko, M. V.

    2018-01-01

    In a closed single-particle quantum system, spatial disorder induces Anderson localization of eigenstates and halts wave propagation. The phenomenon is vulnerable to interaction with environment and decoherence that is believed to restore normal diffusion. We demonstrate that for a class of experimentally feasible non-Hermitian dissipators, which admit signatures of localization in asymptotic states, quantum particle opts between diffusive and ballistic regimes, depending on the phase parameter of dissipators, with sticking about localization centers. In a diffusive regime, statistics of quantum jumps is non-Poissonian and has a power-law interval, a footprint of intermittent locking in Anderson modes. Ballistic propagation reflects dispersion of an ordered lattice and introduces the second timescale for jumps, resulting in non-nonmonotonous probability distribution. Hermitian dephasing dissipation makes localization features vanish, and Poissonian jump statistics along with normal diffusion are recovered.

  1. Scaling of interfacial jump conditions

    International Nuclear Information System (INIS)

    Quezada G, S.; Vazquez R, A.; Espinosa P, G.

    2015-09-01

    To model the behavior of a nuclear reactor accurately is needed to have balance models that take into account the different phenomena occurring in the reactor. These balances have to be coupled together through boundary conditions. The boundary conditions have been studied and different treatments have been given to the interface. In this paper is a brief description of some of the interfacial jump conditions that have been proposed in recent years. Also, the scaling of an interfacial jump condition is proposed, for coupling the different materials that are in contact within a nuclear reactor. (Author)

  2. Frequency domain analysis of knock images

    Science.gov (United States)

    Qi, Yunliang; He, Xin; Wang, Zhi; Wang, Jianxin

    2014-12-01

    High speed imaging-based knock analysis has mainly focused on time domain information, e.g. the spark triggered flame speed, the time when end gas auto-ignition occurs and the end gas flame speed after auto-ignition. This study presents a frequency domain analysis on the knock images recorded using a high speed camera with direct photography in a rapid compression machine (RCM). To clearly visualize the pressure wave oscillation in the combustion chamber, the images were high-pass-filtered to extract the luminosity oscillation. The luminosity spectrum was then obtained by applying fast Fourier transform (FFT) to three basic colour components (red, green and blue) of the high-pass-filtered images. Compared to the pressure spectrum, the luminosity spectra better identify the resonant modes of pressure wave oscillation. More importantly, the resonant mode shapes can be clearly visualized by reconstructing the images based on the amplitudes of luminosity spectra at the corresponding resonant frequencies, which agree well with the analytical solutions for mode shapes of gas vibration in a cylindrical cavity.

  3. Pressure Jumps during Drainage in Macroporous Soils

    DEFF Research Database (Denmark)

    Soto, Diego; Paradelo Pérez, Marcos; Corral, A

    2018-01-01

    Tensiometer readings obtained at high resolution during drainage of structured soil columns revealed pressure jumps with long range correlations and burst sequences with a hierarchical structure. The statistical properties of jumps are similar to Haines jumps described in invasion percolation...... processes at pore scale, but they are much larger in amplitude and duration. Pressure jumps can result from transient redistribution of water potential in internal regions of soil and can be triggered during drainage by capillary displacements at the scale of structural pores....

  4. The identification of price jumps

    Czech Academy of Sciences Publication Activity Database

    Hanousek, Jan; Kočenda, Evžen; Novotný, Jan

    2012-01-01

    Roč. 18, č. 1 (2012), s. 53-77 ISSN 0929-9629 R&D Projects: GA ČR(CZ) GAP403/11/0020; GA ČR(CZ) GBP402/12/G097 Institutional support: PRVOUK-P23 Keywords : price jumps * non-parametric testing * financial econometrics Subject RIV: AH - Economics

  5. Regime Jumps in Electricity Prices

    NARCIS (Netherlands)

    R. Huisman (Ronald); R.J. Mahieu (Ronald)

    2001-01-01

    textabstractElectricity prices are known to be very volatile and subject to frequent jumps due to system breakdown, demand shocks, and inelastic supply. As many international electricity markets are in some state of deregulation, more and more participants in these markets are exposed to these

  6. Mesopause Jumps: Observations and Explanation

    Science.gov (United States)

    Luebken, F. J.; Becker, E.; Höffner, J.; Viehl, T. P.; Latteck, R.

    2017-12-01

    Recent high resolution temperature measurements by resonance lidar at Davis (69°S) occasionally showed a sudden mesopause altitude increase by 5km and an associated mesopause temperature decrease by 10K. We present further observations which are closely related to this `mesopause jump', namely the increase of mean height of polar mesospheric summer echoes (PMSE) observed by a VHF radar, very strong westward winds in the upper mesosphere measured by an MF radar, and relatively large eastward winds in the stratosphere taken from reanalysis. We compare to similar observations in the Northern Hemisphere, namely at ALOMAR (69°N) where such mesopause jumps have never been observed. We present a detailed explanation of mesopause jumps. They occur only when stratospheric winds are moderately eastward and mesospheric winds are very large (westward). Under these conditions, gravity waves with comparatively large eastward phase speeds can pass the stratosphere and propagate to the lower thermosphere because their vertical wavelengths in the mesosphere are rather large which implies reduced dynamical stability. When finally breaking in the lower thermosphere, these waves drive an enhanced residual circulation that causes a cold and high-altitude mesopause. The conditions for a mesopause jump occur only in the Southern Hemisphere (SH) and are associated with the late breakdown of the polar vortex.Mesopause jumps are primarily, but not only, observed prior and close to solstice. We also show that during the onset of PMSE in the SH, stratospheric zonal winds are still eastward (up to 30m/s), and that the onset is not closely related to the transition of the stratospheric circulation.

  7. Effects of timing of signal indicating jump directions on knee biomechanics in jump-landing-jump tasks.

    Science.gov (United States)

    Stephenson, Mitchell L; Hinshaw, Taylour J; Wadley, Haley A; Zhu, Qin; Wilson, Margaret A; Byra, Mark; Dai, Boyi

    2018-03-01

    A variety of the available time to react (ATR) has been utilised to study knee biomechanics during reactive jump-landing tasks. The purpose was to quantify knee kinematics and kinetics during a jump-land-jump task of three possible directions as the ATR was reduced. Thirty-four recreational athletes performed 45 trials of a jump-land-jump task, during which the direction of the second jump (lateral, medial or vertical) was indicated before they initiated the first jump, the instant they initiated the first jump, 300 ms before landing, 150 ms before landing or at the instant of landing. Knee joint angles and moments close to the instant of landing were significantly different when the ATR was equal to or more than 300 ms before landing, but became similar when the ATR was 150 ms or 0 ms before landing. As the ATR was decreased, knee moments decreased for the medial jump direction, but increased for the lateral jump direction. When the ATR is shorter than an individual's reaction time, the movement pattern cannot be pre-planned before landing. Knee biomechanics are dependent on the timing of the signal and the subsequent jump direction. Precise control of timing and screening athletes with low ATR are suggested.

  8. Pion-induced knock-out reactions

    International Nuclear Information System (INIS)

    Jain, B.K.; Phatak, S.C.

    1977-01-01

    A strong absorption model for pion-induced Knock-out reactions is proposed. The distortion of the in-coming and out-going pions has been included by (1) computing pion wave number in nuclear medium (dispersive effect) and (2) excluding the central region of the nucleus where the real pion-absorption is dominant (absorption effect). In order to study the dependence of the (π + π + p) reaction on the off-shell pion-nucleon t-matrix, different off-shell extrapolations are used. The magnitude of the cross-sections seems to be sensitive to the type of off-shell extrapolation; their shapes, however, are similar. The theoretical results are compared with experimental data. The agreement between the theoretical results for separable off-shell extrapolation and the data is good. (author)

  9. I'll knock you when I'm ready

    DEFF Research Database (Denmark)

    Rasmussen, Majken Kirkegaard; Krogh, Peter; Lehoux, Natalie

    2012-01-01

    , and the qualities of suggestive interactions that mediate communication. We introduce Knock-Knock as a novel, shape-changing communication medium, and use it as a rhetorical tool to reflect upon the notion of media richness. In doing so, we highlight the value of meaning and language creation that suggestive...

  10. Eliminating graphs by means of parallel knock-out schemes

    NARCIS (Netherlands)

    Broersma, H.J.; Fomin, F.V.; Královic, R.; Woeginger, G.J.

    2007-01-01

    In 1997 Lampert and Slater introduced parallel knock-out schemes, an iterative process on graphs that goes through several rounds. In each round of this process, every vertex eliminates exactly one of its neighbors. The parallel knock-out number of a graph is the minimum number of rounds after which

  11. Eliminating graphs by means of parallel knock-out schemes

    NARCIS (Netherlands)

    Broersma, Haitze J.; Fomin, F.V.; Královič, R.; Woeginger, Gerhard

    In 1997 Lampert and Slater introduced parallel knock-out schemes, an iterative process on graphs that goes through several rounds. In each round of this process, every vertex eliminates exactly one of its neighbors. The parallel knock-out number of a graph is the minimum number of rounds after which

  12. Surface sensitivity of nuclear-knock-out form factors

    International Nuclear Information System (INIS)

    Fratamico, G.

    1984-01-01

    A numerical calculation has been performed to investigate the sensitivity of nuclear-knock-out form factors to nuclear-surface behaviour of bound-state wave functions. The result of our investigation suggests that one can extract the bound-state behaviour at the surface from experimental information on nuclear-knock-out form factors

  13. Efficient gene knock-out and knock-in with transgenic Cas9 in Drosophila.

    Science.gov (United States)

    Xue, Zhaoyu; Ren, Mengda; Wu, Menghua; Dai, Junbiao; Rong, Yikang S; Gao, Guanjun

    2014-03-21

    Bacterial Cas9 nuclease induces site-specific DNA breaks using small gRNA as guides. Cas9 has been successfully introduced into Drosophila for genome editing. Here, we improve the versatility of this method by developing a transgenic system that expresses Cas9 in the Drosophila germline. Using this system, we induced inheritable knock-out mutations by injecting only the gRNA into embryos, achieved highly efficient mutagenesis by expressing gRNA from the promoter of a novel non-coding RNA gene, and recovered homologous recombination-based knock-in of a fluorescent marker at a rate of 4.5% by co-injecting gRNA with a circular DNA donor. Copyright © 2014 Xue et al.

  14. Locomotion of Mexican jumping beans

    International Nuclear Information System (INIS)

    West, Daniel M; K Lal, Ishan; Leamy, Michael J; Hu, David L

    2012-01-01

    The Mexican jumping bean, Laspeyresia saltitans, consists of a hollow seed housing a moth larva. Heating by the sun induces movements by the larva which appear as rolls, jumps and flips by the bean. In this combined experimental, numerical and robotic study, we investigate this unique means of rolling locomotion. Time-lapse videography is used to record bean trajectories across a series of terrain types, including one-dimensional channels and planar surfaces of varying inclination. We find that the shell encumbers the larva's locomotion, decreasing its speed on flat surfaces by threefold. We also observe that the two-dimensional search algorithm of the bean resembles the run-and-tumble search of bacteria. We test this search algorithm using both an agent-based simulation and a wheeled Scribbler robot. The algorithm succeeds in propelling the robot away from regions of high temperature and may have application in biomimetic micro-scale navigation systems. (paper)

  15. Model for polygonal hydraulic jumps

    DEFF Research Database (Denmark)

    Martens, Erik Andreas; Watanabe, Shinya; Bohr, Tomas

    2012-01-01

    We propose a phenomenological model for the polygonal hydraulic jumps discovered by Ellegaard and co-workers [Nature (London) 392, 767 (1998); Nonlinearity 12, 1 (1999); Physica B 228, 1 (1996)], based on the known flow structure for the type-II hydraulic jumps with a "roller" (separation eddy...... nonhydrostatic pressure contributions from surface tension in light of recent observations by Bush and co-workers [J. Fluid Mech. 558, 33 (2006); Phys. Fluids 16, S4 (2004)]. The model can be analyzed by linearization around the circular state, resulting in a parameter relationship for nearly circular polygonal...... states. A truncated but fully nonlinear version of the model can be solved analytically. This simpler model gives rise to polygonal shapes that are very similar to those observed in experiments, even though surface tension is neglected, and the condition for the existence of a polygon with N corners...

  16. Data-Driven Jump Detection Thresholds for Application in Jump Regressions

    Directory of Open Access Journals (Sweden)

    Robert Davies

    2018-03-01

    Full Text Available This paper develops a method to select the threshold in threshold-based jump detection methods. The method is motivated by an analysis of threshold-based jump detection methods in the context of jump-diffusion models. We show that over the range of sampling frequencies a researcher is most likely to encounter that the usual in-fill asymptotics provide a poor guide for selecting the jump threshold. Because of this we develop a sample-based method. Our method estimates the number of jumps over a grid of thresholds and selects the optimal threshold at what we term the ‘take-off’ point in the estimated number of jumps. We show that this method consistently estimates the jumps and their indices as the sampling interval goes to zero. In several Monte Carlo studies we evaluate the performance of our method based on its ability to accurately locate jumps and its ability to distinguish between true jumps and large diffusive moves. In one of these Monte Carlo studies we evaluate the performance of our method in a jump regression context. Finally, we apply our method in two empirical studies. In one we estimate the number of jumps and report the jump threshold our method selects for three commonly used market indices. In the other empirical application we perform a series of jump regressions using our method to select the jump threshold.

  17. Pressure indication during knocking conditions; Druckindizierung bei klopfender Verbrennung

    Energy Technology Data Exchange (ETDEWEB)

    Bertola, A.; Stadler, J.; Walter, T.; Wolfer, P. [Kistler Instrumente AG Winterthur (Switzerland); Gossweiler, C. [Fachhochschule Nordwestschweiz ITFE (Switzerland); Rothe, M. [Karlsruhe Univ. (Germany). Inst. fuer Kolbenmaschinen

    2006-07-01

    Depending on its frequency and intensity, knocking combustion can cause engine damage due to excessive thermal or mechanical stress on components. During knocking combustion, the cylinder pressure signal is overlaid with high-frequency pressure oscillations. Reliable detection of the knock timing and quantification of the knock intensity based on local measurement of the cylinder pressure demand for particular care, especially when it comes to selecting and adapting the sensor technology and also during the evaluation process using customary knock analysis methods. This publication examines various types of cylinder pressure sensors, how they are installed in the combustion chamber, the effect of sensor positioning and assesses them with regard to accuracy. Finally, on the basis of the test results, recommendations are given for selecting sensors and adapting them within the combustion chamber. A crucial factor for pressure measurement during knocking combustion is the sensor position within the combustion chamber. The sensor type is of secondary importance; at most, cavities between the combustion chamber and the sensor may influence the measuring signal. To assess the sensitivity of the knock evaluation algorithms to various mounting positions and sensor types, it is advisable to carry out comparative measurements between different sensor positions and the measuring spark plug. (orig.)

  18. A Reading of Joseph Conrad's The Tale

    OpenAIRE

    Zadeh, Mohammad Reza Modarres

    2013-01-01

    The Tale is a short story by Joseph Conrad. Typical of a Conrad story it is set at sea. The sea is symbolic of the unconscious and this story may be read as a story of the unconscious. On the outside, it seems simple; a man tells a woman a tale of the commanding officer of a patrol ship who gives false directions to another ship and sends it to its doom. In between the lines of the seemingly simple plot, however, can be read another tale; one which speaks of a human sea deeper than the sea of...

  19. Real and étale cohomology

    CERN Document Server

    Scheiderer, Claus

    1994-01-01

    This book makes a systematic study of the relations between the étale cohomology of a scheme and the orderings of its residue fields. A major result is that in high degrees, étale cohomology is cohomology of the real spectrum. It also contains new contributions in group cohomology and in topos theory. It is of interest to graduate students and researchers who work in algebraic geometry (not only real) and have some familiarity with the basics of étale cohomology and Grothendieck sites. Independently, it is of interest to people working in the cohomology theory of groups or in topos theory.

  20. Tales of physicists and mathematicians

    CERN Document Server

    Gindikin, Semyon Grigorevich

    1988-01-01

    This revised and greatly expanded second edition of the classic Russian text Tales of Mathematicians and Physicists contains a wealth of new information about the lives and accomplishments of more than a dozen scientists throughout history. Included are individuals from the late nineteenth century: Klein, Poincaré, Ramanujan, and Penrose, as well as renowned figures from earlier eras, such as Leibniz, Euler, Lagrange, and Laplace. A unique mixture of mathematics, physics, and history, this volume provides biographical glimpses of scientists and their contributions in the context of the social and political background of their times. The author examines many original sources, from the scientists’ research papers to their personal documents and letters to friends and family; furthermore, detailed mathematical arguments and diagrams are supplied to help explain some of the most significant discoveries in calculus, celestial mechanics, number theory, and modern relativity. What emerges are intriguing, multifac...

  1. Psychophysiological response in parachute jumps, the effect of experience and type of jump.

    Science.gov (United States)

    Clemente-Suárez, Vicente Javier; Robles-Pérez, José Juan; Fernández-Lucas, Jesús

    2017-10-01

    We aimed to analyse the effect of experience and type of parachute jump on the psychophysiological responses of jumpers. We analysed blood oxygen saturation, heart rate, blood glucose, lactate and creatinkinase, leg strength, isometric hand strength, cortical arousal, specific fine motor skills, self-confidence and cognition, and somatic and state anxiety, before and after four different parachute jumps: a sport parachute jump, a manual tactical parachute jump, tandem pilots, and tandem passengers. Independently of the parachute jump, the psychophysiological responses of experienced paratroopers were not affected by the jumps, except for an increase in anaerobic metabolism. Novice parachute jumpers presented a higher psychophysiological stress response than the experienced jumpers, together with a large anticipatory anxiety response before the jump; however, this decreased after the jump, although the high physiological activation was maintained. This information could be used by civil and military paratroopers' instructors to improve their training programmes. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. TALE nucleases and next generation GM crops.

    KAUST Repository

    Mahfouz, Magdy M.; Li, Lixin

    2011-01-01

    Site-specific and adaptable DNA binding domains are essential modules to develop genome engineering technologies for crop improvement. Transcription activator-like effectors (TALEs) proteins are used to provide a highly specific and adaptable DNA

  3. "Thou" and "Ye" in Chaucer's "Clerk's Tale."

    Science.gov (United States)

    Wilcockson, Colin

    1980-01-01

    Examines the use of the second person pronoun in Chaucer's "Clerk's Tale" to demonstrate that students of medieval texts may well miss important areas of meaning if they fail to give adequate attention to the historical study of language. (GT)

  4. Knock-on accident prevention in a chemical cluster

    NARCIS (Netherlands)

    Reniers, Genserik L L; Dullaert, W.

    Empirical research has revealed that safety managers acknowledge the importance of cross-company cooperation for knock-on risk reduction. This paper presents a decision support software tool, called DomPrevPlanning

  5. Dynamic jump intensities and risk premiums

    DEFF Research Database (Denmark)

    Christoffersen, Peter; Ornthanalai, Chayawat; Jacobs, Kris

    2012-01-01

    We build a new class of discrete-time models that are relatively easy to estimate using returns and/or options. The distribution of returns is driven by two factors: dynamic volatility and dynamic jump intensity. Each factor has its own risk premium. The models significantly outperform standard...... models without jumps when estimated on S&P500 returns. We find very strong support for time-varying jump intensities. Compared to the risk premium on dynamic volatility, the risk premium on the dynamic jump intensity has a much larger impact on option prices. We confirm these findings using joint...

  6. Characteristics of Air Entrainment in Hydraulic Jump

    Science.gov (United States)

    Albarkani, M. S. S.; Tan, L. W.; Al-Gheethi, A.

    2018-04-01

    The characteristics of hydraulic jump, especially the air entrainment within jump is still not properly understood. Therefore, the current work aimed to determine the size and number of air entrainment formed in hydraulic jump at three different Froude numbers and to obtain the relationship between Froude number with the size and number of air entrainment in hydraulic jump. Experiments of hydraulic jump were conducted in a 10 m long and 0.3 m wide Armfield S6MKII glass-sided tilting flume. Hydraulic jumps were produced by flow under sluice gate with varying Froude number. The air entrainment of the hydraulic jump was captured with a Canon Power Shot SX40 HS digital camera in video format at 24 frames per second. Three discharges have been considered, i.e. 0.010 m3/s, 0.011 m3/s, and 0.013 m3/s. For hydraulic jump formed in each discharge, 32 frames were selected for the purpose of analysing the size and number of air entrainment in hydraulic jump. The results revealed that that there is a tendency to have greater range in sizes of air bubbles as Fr1 increases. Experiments with Fr1 = 7.547. 7.707, and 7.924 shown that the number of air bubbles increases exponentially with Fr1 at a relationship of N = 1.3814 e 0.9795Fr1.

  7. Improved safety in ski jumping.

    Science.gov (United States)

    Wester, K

    1988-01-01

    Among approximately 2,600 licensed Norwegian ski jumpers, only three injuries that caused a permanent medical disability of at least 10% were incurred during the 5 year period from 1982 through 1986. When compared to the previous 5 year period (1977 to 1981), a dramatic improvement in safety is seen, as both number and severity of such injuries were markedly reduced. There are several probable reasons for this improved safety record: better preparation of the jumps, the return to using only one standard heel block, and the fact that coaches are being more responsible, especially with younger jumpers.

  8. Tegn kan også Tale

    DEFF Research Database (Denmark)

    Fischer, Jutta; Niebe, Susanne; Bisgaard, Hanne

    "Tegn kan også Tale" er et begyndermateriale til undervisning af syns- og hørehæmmede døvblindblevne i taktil tegnstøttet kommunikation - en ny taktil kommunikationsform, som bygger på det danske sprog og bruger tegn og andre elementer fra døves tegnsprog. Tegn kan også Tale´ henvender sig primær...

  9. Kinematics and Kinetics of Squats, Drop Jumps and Imitation Jumps of Ski Jumpers.

    Science.gov (United States)

    Pauli, Carole A; Keller, Melanie; Ammann, Fabian; Hübner, Klaus; Lindorfer, Julia; Taylor, William R; Lorenzetti, Silvio

    2016-03-01

    Squats, drop jumps, and imitation jumps are commonly used training exercises in ski jumping to enhance maximum force, explosive force, and sport-specific skills. The purpose of this study was to evaluate the kinetics and kinematics of training exercises in ski jumping and to find objective parameters in training exercises that most correlate with the competition performance of ski jumpers. To this end, barbell squats, drop jumps, and imitation jumps were measured in a laboratory environment for 10 elite ski jumpers. Force and motion data were captured, and the influence of maximum vertical force, force difference, vertical take-off velocity, knee moments, knee joint power, and a knee valgus/varus index was evaluated and correlated with their season jump performance. The results indicate that, especially for the imitation jumps, a good correlation exists between the vertical take-off velocity and the personal jump performance on the hill (R = 0.718). Importantly, however, the more the athletes tended toward a valgus knee alignment during the measured movements, the worse their performance (R = 0.729 imitation jumps; R = 0.685 squats). Although an evaluation of the athletes' lower limb alignment during competitive jumping on the hill is still required, these preliminary data suggest that performance training should additionally concentrate on improving knee alignment to increase ski jumping performance.

  10. Separation and pattern formation in hydraulic jumps

    DEFF Research Database (Denmark)

    Bohr, Tomas; Ellegaard, C.; Hansen, A. Espe

    1998-01-01

    We present theory and experiments on the circular hydraulic jump in the stationary regime. The theory can handle the situation in which the fluid flows over an edge far away from the jump. In the experiments the external height is controlled, and a series of transitions in the flow structure appe...

  11. Biomechanical analysis of drop and countermovement jumps

    NARCIS (Netherlands)

    Bobbert, M. F.; Mackay, M.T.; Schinkelshoek, D.; Huijing, P. A.; van Ingen Schenau, G. J.

    For 13 subjects the performance of drop jumps from a height of 40 cm (DJ) and of countermovement jumps (CMJ) was analysed and compared. From force plate and cine data biomechanical variables including forces, moments, power output and amount of work done were calculated for hip, knee and ankle

  12. Jump Detection in the Danish Stock Market

    DEFF Research Database (Denmark)

    Høg, Esben

    2002-01-01

    It is well known in financial economics that stock market return data are often modelled by a diffusion process with some regular drift function. Occasionally, however, sudden changes or jumps occur in the return data. Wavelet scaling methods are used to detect jumps and cusps in stock market...

  13. You Say Jump, I Say How High?

    DEFF Research Database (Denmark)

    Fasterhold, Martin; Pichlmair, Martin; Holmgård, Christoffer

    This paper explores the design of jumping in 2D platform games. Through creating a method for measuring existing games, applying this method to a selection of different platformer games, and analysing the results, the paper arrives at a comprehensive data model for jumping. The model supports the...

  14. Usefulness of the jump-and-reach test in assessment of vertical jump performance.

    Science.gov (United States)

    Menzel, Hans-Joachim; Chagas, Mauro H; Szmuchrowski, Leszek A; Araujo, Silvia R; Campos, Carlos E; Giannetti, Marcus R

    2010-02-01

    The objective was to estimate the reliability and criterion-related validity of the Jump-and-Reach Test for the assessment of squat, countermovement, and drop jump performance of 32 male Brazilian professional volleyball players. Performance of squat, countermovement, and drop jumps with different dropping heights was assessed on the Jump-and-Reach Test and the measurement of flight time, then compared across different jump trials. The very high reliability coefficients of both assessment methods and the lower correlation coefficients between scores on the assessments indicate a very high consistency of each method but only moderate covariation, which means that they measure partly different items. As a consequence, the Jump-and-Reach Test has good ecological validity in situations when reaching height during the flight phase is critical for performance (e.g., basketball and volleyball) but only limited accuracy for the assessment of vertical impulse production with different jump techniques and conditions.

  15. A review on the basketball jump shot.

    Science.gov (United States)

    Okazaki, Victor H A; Rodacki, André L F; Satern, Miriam N

    2015-06-01

    The ability to shoot an effective jump shot in the sport of basketball is critical to a player's success. In an attempt to better understand the aspects related to expert performance, researchers have investigated successful free throws and jump shots of various basketball players and identified movement variables that contribute to their success. The purpose of this study was to complete a systematic review of the scientific literature on the basketball free throw and jump shot for the purpose of revealing the critical components of shooting that coaches, teachers, and players should focus on when teaching, learning, practising, and performing a jump shot. The results of this review are presented in three sections: (a) variables that affect ball trajectory, (b) phases of the jump shot, and (c) additional variables that influence shooting.

  16. Theory of boiling-up jump

    International Nuclear Information System (INIS)

    Labuntsov, D.A.; Avdeev, A.A.

    1981-01-01

    Concept of boiling-up jump representing a zone of intense volume boiling-up separating overtaking flow of overheated metastable liquid from an area of equilibrium flow located below along the flow is introduced. It is shown that boiling-up jump is a shock wave of rarefaction. It is concluded that entropy increment occurs on the jump. Characteristics of adiabatic shock wave curve of boiling- up in ''pressure-specific volume'' coordinates have been found and its form has been investigated. Stability of boiling-up jump has been analyzed as well. On the basis of approach developed analysis is carried out on the shock adiobatic curve of condensation. Concept of boiling-up jump may be applied to the analysis of boiling-up processes when flowing liquid through packings during emergency pressure drop etc [ru

  17. Kinematics and Kinetics of Squats, Drop Jumps and Imitation Jumps of Ski Jumpers

    Science.gov (United States)

    Pauli, Carole A.; Keller, Melanie; Ammann, Fabian; Hübner, Klaus; Lindorfer, Julia; Taylor, William R.

    2016-01-01

    Abstract Pauli, CA, Keller, M, Ammann, F, Hübner, K, Lindorfer, J, Taylor, WR, and Lorenzetti, S. Kinematics and kinetics of squats, drop jumps and imitation jumps of ski jumpers. J Strength Cond Res 30(3): 643–652, 2016—Squats, drop jumps, and imitation jumps are commonly used training exercises in ski jumping to enhance maximum force, explosive force, and sport-specific skills. The purpose of this study was to evaluate the kinetics and kinematics of training exercises in ski jumping and to find objective parameters in training exercises that most correlate with the competition performance of ski jumpers. To this end, barbell squats, drop jumps, and imitation jumps were measured in a laboratory environment for 10 elite ski jumpers. Force and motion data were captured, and the influence of maximum vertical force, force difference, vertical take-off velocity, knee moments, knee joint power, and a knee valgus/varus index was evaluated and correlated with their season jump performance. The results indicate that, especially for the imitation jumps, a good correlation exists between the vertical take-off velocity and the personal jump performance on the hill (R = 0.718). Importantly, however, the more the athletes tended toward a valgus knee alignment during the measured movements, the worse their performance (R = 0.729 imitation jumps; R = 0.685 squats). Although an evaluation of the athletes' lower limb alignment during competitive jumping on the hill is still required, these preliminary data suggest that performance training should additionally concentrate on improving knee alignment to increase ski jumping performance. PMID:26418370

  18. Mobile Jump Assessment (mJump): A Descriptive and Inferential Study.

    Science.gov (United States)

    Mateos-Angulo, Alvaro; Galán-Mercant, Alejandro; Cuesta-Vargas, Antonio

    2015-08-26

    Vertical jump tests are used in athletics and rehabilitation to measure physical performance in people of different age ranges and fitness. Jumping ability can be analyzed through different variables, and the most commonly used are fly time and jump height. They can be obtained by a variety of measuring devices, but most are limited to laboratory use only. The current generation of smartphones contains inertial sensors that are able to record kinematic variables for human motion analysis, since they are tools for easy access and portability for clinical use. The aim of this study was to describe and analyze the kinematics characteristics using the inertial sensor incorporated in the iPhone 4S, the lower limbs strength through a manual dynamometer, and the jump variables obtained with a contact mat in the squat jump and countermovement jump tests (fly time and jump height) from a cohort of healthy people. A cross sectional study was conducted on a population of healthy young adults. Twenty-seven participants performed three trials (n=81 jumps) of squat jump and countermovement jump tests. Acceleration variables were measured through a smartphone's inertial sensor. Additionally, jump variables from a contact mat and lower limbs dynamometry were collected. In the present study, the kinematic variables derived from acceleration through the inertial sensor of a smartphone iPhone 4S, dynamometry of lower limbs with a handheld dynamometer, and the height and flight time with a contact mat have been described in vertical jump tests from a cohort of young healthy subjects. The development of the execution has been described, examined and identified in a squat jump test and countermovement jump test under acceleration variables that were obtained with the smartphone. The built-in iPhone 4S inertial sensor is able to measure acceleration variables while performing vertical jump tests for the squat jump and countermovement jump in healthy young adults. The acceleration

  19. A Fairy-Tale Landscape

    Science.gov (United States)

    2008-01-01

    [figure removed for brevity, see original site] Click on image for animation Fun, fairy-tale nicknames have been assigned to features in this animated view of the workspace reachable by the robotic arm of NASA's Phoenix Mars Lander. For example, 'Sleepy Hollow' denotes a trench and 'Headless' designates a rock. A 'National Park,' marked by purple text and a purple arrow, has been set aside for protection until scientists and engineers have tested the operation of the robotic scoop. First touches with the scoop will be to the left of the 'National Park' line. Scientists use such informal names for easy identification of features of interest during the mission. In this view, rocks are circled in yellow, other areas of interest in green. The images were taken by the lander's 7-foot mast camera, called the Surface Stereo Imager. The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

  20. The Category of Time in Fairy Tales: Searching for Folk Calendar Time in the Estonian Fairy Tale Corpus

    Directory of Open Access Journals (Sweden)

    Mairi Kaasik

    2011-03-01

    Full Text Available The article examines how folk calendar holidays are represented in Estonian fairy tales. It introduces some views presented in folklore studies about the concept of time in fairy tales and finds parallels with them in the Estonian context. The analysis relies on the digital corpus of Estonian fairy tales (5400 variants, created from the texts found in the Estonian Folklore Archives by the Fairy Tale Project of the Department of Estonian and Comparative Folklore, University of Tartu. Folk calendar holidays occur in Estonian fairy tales relatively seldom; most often these are holidays that occupy a significant place in the Estonian folk calendar (Christmas, St. John’s Day, Easter, St. George’s Day. Calendar holidays are notably mentioned more often in tale types which remain on the borderline between the fairy tale and the legend or the fairy tale and the religious tale. In Estonian fairy tales, calendar holidays are used on three levels of meaning: (1 the holiday is organically associated with the tale type; it has an essential role in the plot of the tale; (2 to a certain extent, the holiday could be replaced by another holiday having an analogous meaning; (3 the holiday forms an unimportant or occasional addition to the tale.

  1. Robust, synergistic regulation of human gene expression using TALE activators.

    Science.gov (United States)

    Maeder, Morgan L; Linder, Samantha J; Reyon, Deepak; Angstman, James F; Fu, Yanfang; Sander, Jeffry D; Joung, J Keith

    2013-03-01

    Artificial activators designed using transcription activator-like effector (TALE) technology have broad utility, but previous studies suggest that these monomeric proteins often exhibit low activities. Here we demonstrate that TALE activators can robustly function individually or in synergistic combinations to increase expression of endogenous human genes over wide dynamic ranges. These findings will encourage applications of TALE activators for research and therapy, and guide design of monomeric TALE-based fusion proteins.

  2. Realized Jump Risk and Equity Return in China

    Directory of Open Access Journals (Sweden)

    Guojin Chen

    2014-01-01

    Full Text Available We utilize the realized jump components to explore a new jump (including nonsystematic jump and systematic jump risk factor model. After estimating daily realized jumps from high-frequency transaction data of the Chinese A-share stocks, we calculate monthly jump size, monthly jump standard deviation, and monthly jump arrival rate and then use those monthly jump factors to explain the return of the following month. Our empirical results show that the jump tail risk can explain the equity return. For the large capital-size stocks, large cap stock portfolios, and index, one-month lagged jump risk factor significantly explains the asset return variation. Our results remain the same even when we add the size and value factors in the robustness tests.

  3. The effect of assisted jumping on vertical jump height in high-performance volleyball players.

    Science.gov (United States)

    Sheppard, Jeremy M; Dingley, Andrew A; Janssen, Ina; Spratford, Wayne; Chapman, Dale W; Newton, Robert U

    2011-01-01

    Assisted jumping may be useful in training higher concentric movement speed in jumping, thereby potentially increasing the jumping abilities of athletes. The purpose of this study was to evaluate the effects of assisted jump training on counter-movement vertical jump (CMVJ) and spike jump (SPJ) ability in a group of elite male volleyball players. Seven junior national team volleyball players (18.0±1.0 yrs, 200.4±6.7 cm, and 84.0±7.2 kg) participated in this within-subjects cross-over counter-balanced training study. Assisted training involved 3 sessions per week of CMVJ training with 10 kg of assistance, applied through use of a bungee system, whilst normal jump training involved equated volume of unassisted counter-movement vertical jumps. Training periods were 5 weeks duration, with a 3-week wash-out separating them. Prior to and at the conclusion of each training period jump testing for CMVJ and SPJ height was conducted. Assisted jump training resulted in gains of 2.7±0.7 cm (pSports Medicine Australia. All rights reserved.

  4. A Tale within a Tale: Mise en Abyme Adaptations of the Twenty-first Century

    Directory of Open Access Journals (Sweden)

    Željka Flegar

    2017-12-01

    Full Text Available In accord with the promise made by Henry Jenkins that “old and new media will interact in ever more complex ways” (Convergence Culture 6, this research observes metamodern fairy tale adaptations of the twenty-first century in light of Christina Bacchilega’s construct of the fairy-tale web and Henry Jenkins’ theory of convergence culture and transmedia storytelling. The research will address the growing trend of embedding “wonder tale” collections within the context of a larger narrative as an artefact of significance, power, and material value. Although original tales with known authorship, these fairy tale adaptations are appended to the mythology and culture of the fantastic secondary worlds. Such texts tend to be parodic, subversive, and even carnivalesque (Bakhtin; Stephens, providing a commentary on the culture of their origin, as well as our own. By blending cultures, styles, and formats, mise en abyme wonder tales also result in the empowerment of specifically marginalised groups. Generally defined as spin-offs that are otherwise a part of a complex inter- and hypertextual web, these fairy tale collections constitute a metafictional body of knowledge and wisdom. In the digital era much focus is placed on multimodal, hypertextual, and transmedia narratives with a significant influence of fandom on the production of such literary works. The study will focus on the popular examples of such practice, J.K. Rowling’s Tales of Beedle the Bard (2007/2008 and Ransom Riggs’ Tales of the Peculiar (2016, in order to define mise en abyme fairy tale adaptations, as well as to discuss their cultural significance and function.

  5. Strength Determinants of Jump Height in the Jump Throw Movement in Women Handball Players.

    Science.gov (United States)

    McGhie, David; Østerås, Sindre; Ettema, Gertjan; Paulsen, Gøran; Sandbakk, Øyvind

    2018-06-08

    McGhie, D, Østerås, S, Ettema, G, Paulsen, G, and Sandbakk, Ø. Strength determinants of jump height in the jump throw movement in women handball players. J Strength Cond Res XX(X): 000-000, 2018-The purpose of the study was to improve the understanding of the strength demands of a handball-specific jump through examining the associations between jump height in a jump throw jump (JTJ) and measures of lower-body maximum strength and impulse in handball players. For comparison, whether the associations between jump height and strength differed between the JTJ and the customarily used countermovement jump (CMJ) was also examined. Twenty women handball players from a Norwegian top division club participated in the study. Jump height was measured in the JTJ and in unilateral and bilateral CMJ. Lower-body strength (maximum isometric force, one-repetition maximum [1RM], impulse at ∼60% and ∼35% 1RM) was measured in seated leg press. The associations between jump height and strength were assessed with correlation analyses and t-tests of dependent r's were performed to determine if correlations differed between jump tests. Only impulse at ∼35% 1RM correlated significantly with JTJ height (p jump height and strength were significantly weaker in the JTJ than in both CMJ tests for all strength measures (p = 0.001-0.044) except one. Maximum strength and impulse at ∼60% 1RM did not seem to sufficiently capture the capabilities associated with JTJ height, highlighting the importance of employing tests targeting performance-relevant neuromuscular characteristics when assessing jump-related strength in handball players. Further, CMJ height seemed to represent a wider range of strength capabilities and care should be taken when using it as a proxy for handball-specific movements.

  6. TALE nucleases and next generation GM crops.

    KAUST Repository

    Mahfouz, Magdy M.

    2011-04-01

    Site-specific and adaptable DNA binding domains are essential modules to develop genome engineering technologies for crop improvement. Transcription activator-like effectors (TALEs) proteins are used to provide a highly specific and adaptable DNA binding modules. TALE chimeric nucleases (TALENs) were used to generate site-specific double strand breaks (DSBs) in vitro and in yeast, Caenorhabditis elegans, mammalian and plant cells. The genomic DSBs can be generated at predefined and user-selected loci and repaired by either the non-homologous end joining (NHEJ) or homology dependent repair (HDR). Thus, TALENs can be used to achieve site-specific gene addition, stacking, deletion or inactivation. TALE-based genome engineering tools should be powerful to develop new agricultural biotechnology approaches for crop improvement. Here, we discuss the recent research and the potential applications of TALENs to accelerate the generation of genomic variants through targeted mutagenesis and to produce a non-transgenic GM crops with the desired phenotype.

  7. Knock-on electrons in WA98 silicon drift detector

    International Nuclear Information System (INIS)

    Eliseev, S.

    1997-01-01

    Silicon Drift Detector is used to estimate production of knock-on electrons created by passage of 158 GeV /u fully stripped Pb ion through thick lead target. Analysed data were collected in 1995 during Pb+Pb run in WA98 heavy ion experiment at CERN SPS. Information from WA98 Cherenkov beam counter makes it possible to classify events according to number of additional Pb ions which have during detector's read-out time passed through the target without nuclear interaction. Events with one and none pile-up ion are used for statistical separation of knock-on electrons from all detected charged particles. Resulting inclusive spectra of knock-on electrons are compared with GRANT simulations and good agreement is found. (author)

  8. Singing Dead Tales to Life: Rhetorical Strategies in Shandong Fast Tales

    Directory of Open Access Journals (Sweden)

    Eric Shepherd

    2011-03-01

    Full Text Available This article provides a brief overview of the Shandong fast tale tradition, a Chinese oral performance genre that began in rural northern China approximately four hundred years ago. Included in this overview are brief descriptions of the origins, audience composition, tale length, repertoire, and major characteristics of the stories and performances. Following these descriptions is a discussion of the expressive and rhetorical devices used by the tale-tellers as they perform live, such as formulaic language, repetition, character roles, shifts in speech register, body language, facial expressions, memory, onomatopoeia, physical humor, and hyperbolic language.

  9. The AGS γt-jump system

    International Nuclear Information System (INIS)

    Syphers, M.J.; Ahrens, L.; van Asselt, W.; Brennan, J.M.

    1994-01-01

    In an attempt to generate a lossless crossing of an accelerator's transition energy, one procedure is to alter the transition energy of the accelerator quickly as the beam passes through this energy region by changing the optics of the lattice -- a so-called ''transition jump,'' or '' γt -jump'' scheme. Such a system was first implemented at CERN and later adopted at other accelerator laboratories. A scheme for the AGS was developed in 1986. A description of the AGS γt -jump system, and recent results from its commissioning are presented in this report

  10. Predicting vertical jump height from bar velocity.

    Science.gov (United States)

    García-Ramos, Amador; Štirn, Igor; Padial, Paulino; Argüelles-Cienfuegos, Javier; De la Fuente, Blanca; Strojnik, Vojko; Feriche, Belén

    2015-06-01

    The objective of the study was to assess the use of maximum (Vmax) and final propulsive phase (FPV) bar velocity to predict jump height in the weighted jump squat. FPV was defined as the velocity reached just before bar acceleration was lower than gravity (-9.81 m·s(-2)). Vertical jump height was calculated from the take-off velocity (Vtake-off) provided by a force platform. Thirty swimmers belonging to the National Slovenian swimming team performed a jump squat incremental loading test, lifting 25%, 50%, 75% and 100% of body weight in a Smith machine. Jump performance was simultaneously monitored using an AMTI portable force platform and a linear velocity transducer attached to the barbell. Simple linear regression was used to estimate jump height from the Vmax and FPV recorded by the linear velocity transducer. Vmax (y = 16.577x - 16.384) was able to explain 93% of jump height variance with a standard error of the estimate of 1.47 cm. FPV (y = 12.828x - 6.504) was able to explain 91% of jump height variance with a standard error of the estimate of 1.66 cm. Despite that both variables resulted to be good predictors, heteroscedasticity in the differences between FPV and Vtake-off was observed (r(2) = 0.307), while the differences between Vmax and Vtake-off were homogenously distributed (r(2) = 0.071). These results suggest that Vmax is a valid tool for estimating vertical jump height in a loaded jump squat test performed in a Smith machine. Key pointsVertical jump height in the loaded jump squat can be estimated with acceptable precision from the maximum bar velocity recorded by a linear velocity transducer.The relationship between the point at which bar acceleration is less than -9.81 m·s(-2) and the real take-off is affected by the velocity of movement.Mean propulsive velocity recorded by a linear velocity transducer does not appear to be optimal to monitor ballistic exercise performance.

  11. Generation of Knock-in Mouse by Genome Editing.

    Science.gov (United States)

    Fujii, Wataru

    2017-01-01

    Knock-in mice are useful for evaluating endogenous gene expressions and functions in vivo. Instead of the conventional gene-targeting method using embryonic stem cells, an exogenous DNA sequence can be inserted into the target locus in the zygote using genome editing technology. In this chapter, I describe the generation of epitope-tagged mice using engineered endonuclease and single-stranded oligodeoxynucleotide through the mouse zygote as an example of how to generate a knock-in mouse by genome editing.

  12. Measurements of K shell absorption jump factors and jump ratios using EDXRF technique

    Science.gov (United States)

    Kacal, Mustafa Recep; Han, İbrahim; Akman, Ferdi

    2015-04-01

    In the present work, the K-shell absorption jump factors and jump ratios for 30 elements between Ti ( Z = 22) and Er ( Z = 68) were measured by energy dispersive X-ray fluorescence (EDXRF) technique. The jump factors and jump ratios for these elements were determined by measuring the K shell fluorescence parameters such as the Kα X-ray production cross-sections, K shell fluorescence yields, Kβ-to- Kα X-rays intensity ratios, total atomic absorption cross sections and mass attenuation coefficients. The measurements were performed using an Am-241 radioactive point source and a Si (Li) detector in direct excitation and transmission experimental geometry. The results for jump factors and jump ratios were compared with theoretically calculated and the ones available in the literature.

  13. The Effects of Aquatic Plyometric Training on Repeated Jumps, Drop Jumps and Muscle Damage.

    Science.gov (United States)

    Jurado-Lavanant, A; Alvero-Cruz, J R; Pareja-Blanco, F; Melero-Romero, C; Rodríguez-Rosell, D; Fernandez-Garcia, J C

    2015-09-22

    The purpose of this study was to compare the effects of land- vs. aquatic based plyometric training programs on the drop jump, repeated jump performance and muscle damage. Sixty-five male students were randomly assigned to one of 3 groups: aquatic plyometric training group (APT), plyometric training group (PT) and control group (CG). Both experimental groups trained twice a week for 10 weeks performing the same number of sets and total jumps. The following variables were measured prior to, halfway through and after the training programs: creatine kinase (CK) concentration, maximal height during a drop jump from the height of 30 (DJ30) and 50 cm (DJ50), and mean height during a repeated vertical jump test (RJ). The training program resulted in a significant increase (Pplyometric training, PT produced greater gains on reactive jumps performance than APT. © Georg Thieme Verlag KG Stuttgart · New York.

  14. Option Panels in Pure-Jump Settings

    DEFF Research Database (Denmark)

    Andersen, Torben Gustav; Fusari, Nicola; Todorov, Viktor

    We develop parametric inference procedures for large panels of noisy option data in the setting where the underlying process is of pure-jump type, i.e., evolve only through a sequence of jumps. The panel consists of options written on the underlying asset with a (different) set of strikes...... specification for the risk-neutral asset return dynamics, the option prices are nonlinear functions of a time-invariant parameter vector and a time-varying latent state vector (or factors). Furthermore, no-arbitrage restrictions impose a direct link between some of the quantities that may be identified from...... the return and option data. These include the so-called jump activity index as well as the time-varying jump intensity. We propose penalized least squares estimation in which we minimize L_2 distance between observed and model-implied options and further penalize for the deviation of model-implied quantities...

  15. Microscopic models of quantum-jump superoperators

    International Nuclear Information System (INIS)

    Dodonov, A.V.; Mizrahi, S.S.; Dodonov, V.V.

    2005-01-01

    We discuss the quantum-jump operation in an open system and show that jump superoperators related to a system under measurement can be derived from the interaction of that system with a quantum measurement apparatus. We give two examples for the interaction of a monochromatic electromagnetic field in a cavity (the system) with two-level atoms and with a harmonic oscillator (representing two different kinds of detectors). We show that the derived quantum-jump superoperators have a 'nonlinear' form Jρ=γ diag[F(n)aρa † F(n)], where the concrete form of the function F(n) depends on assumptions made about the interaction between the system and detector. Under certain conditions the asymptotical power-law dependence F(n)=(n+1) -β is obtained. A continuous transition to the standard Srinivas-Davies form of the quantum-jump superoperator (corresponding to β=0) is shown

  16. Human Long Jump — A Deductive Approach

    Directory of Open Access Journals (Sweden)

    Miloš Jovanović

    2012-10-01

    Full Text Available This paper presents a useful application of a generalized approach to the modelling of human and humanoid motion using the deductive approach. It starts with formulating a completely general problem and deriving different real situations as special cases. The concept and the software realization are verified by comparing the results with the ones obtained using “classical” software for one well-known particular problem – biped walking. New applicability and potentials of the proposed method are demonstrated by simulation of a selected example – the long jump. The simulated motion included jumping and landing on the feet (after a jump. Additional analysis is done in the paper regarding the joint torque and joint angle during the jumping. Separate stages of the simulation are defined and explained.

  17. Volatility jumps and their economic determinants

    DEFF Research Database (Denmark)

    Caporin, Massimiliano; Rossi, Eduardo; Santucci de Magistris, Paolo

    that there is a positive probability of jumps in volatility. A common factor in the volatility jumps is shown to be related to a set of financial covariates (such as variance risk premium, S&P500 volume, credit-default swap, and federal fund rates). The credit-default swap on US banks and variance risk premium have...... predictive power on expected jump moves, thus confirming the common interpretation that sudden and large increases in equity volatility can be anticipated by credit deterioration of the US bank sector as well as changes in the market expectations of future risks. Finally, the model is extended to incorporate...... the credit-default swap and the variance risk premium in the dynamics of the jump size and intensity....

  18. A simple strategy for jumping straight up.

    Science.gov (United States)

    Hemami, Hooshang; Wyman, Bostwick F

    2012-05-01

    Jumping from a stationary standing position into the air is a transition from a constrained motion in contact with the ground to an unconstrained system not in contact with the ground. A simple case of the jump, as it applies to humans, robots and humanoids, is studied in this paper. The dynamics of the constrained rigid body are expanded to define a larger system that accommodates the jump. The formulation is applied to a four-link, three-dimensional system in order to articulate the ballistic motion involved. The activity of the muscular system and the role of the major sagittal muscle groups are demonstrated. The control strategy, involving state feedback and central feed forward signals, is formulated and computer simulations are presented to assess the feasibility of the formulations, the strategy and the jump. Copyright © 2012 Elsevier Inc. All rights reserved.

  19. How quick is a quantum jump?

    International Nuclear Information System (INIS)

    Schulman, L.S.

    1997-01-01

    Although the only time scale one ordinarily associates with a quantum transition is its lifetime, observations of ''quantum jumps'' in recent years show that the actual transition time is much shorter. I define a ''jump time'' as the time scale such that perturbations occurring at intervals of this duration affect the decay. In terms of the ''Zeno time'' (related to the second moment of the Hamiltonian) the jump time is τ J is identical to τ 2 Z /τ L . Corroboration is given. I also show that observing the ''jumping'' will not seriously affect the system lifetime, but will affect the linewidth. This is consistent with Bohr's ideas on measurement as well as with a heuristic time-energy uncertainty principle. (author)

  20. A Correction Equation for Jump Height Measured Using the Just Jump System.

    Science.gov (United States)

    McMahon, John J; Jones, Paul A; Comfort, Paul

    2016-05-01

    To determine the concurrent validity and reliability of the popular Just Jump system (JJS) for determining jump height and, if necessary, provide a correction equation for future reference. Eighteen male college athletes performed 3 bilateral countermovement jumps (CMJs) on 2 JJSs (alternative method) that were placed on top of a force platform (criterion method). Two JJSs were used to establish consistency between systems. Jump height was calculated from flight time obtained from the JJS and force platform. Intraclass correlation coefficients (ICCs) demonstrated excellent within-session reliability of the CMJ height measurement derived from both the JJS (ICC = .96, P jump height (0.46 ± 0.09 m vs 0.33 ± 0.08 m) than the force platform (P jump height = (0.8747 × alternative jump height) - 0.0666. The JJS provides a reliable but overestimated measure of jump height. It is suggested, therefore, that practitioners who use the JJS as part of future work apply the correction equation presented in this study to resultant jump-height values.

  1. Jump Horse Safety: Reconciling Public Debate and Australian Thoroughbred Jump Racing Data, 2012–2014

    Directory of Open Access Journals (Sweden)

    Karen Ruse

    2015-10-01

    Full Text Available Thoroughbred jump racing sits in the spotlight of contemporary welfare and ethical debates about horse racing. In Australia, jump racing comprises hurdle and steeplechase races and has ceased in all but two states, Victoria and South Australia. This paper documents the size, geography, composition, and dynamics of Australian jump racing for the 2012, 2013, and 2014 seasons with a focus on debate about risks to horses. We found that the majority of Australian jump racing is regional, based in Victoria, and involves a small group of experienced trainers and jockeys. Australian jump horses are on average 6.4 years of age. The jump career of the majority of horses involves participating in three or less hurdle races and over one season. Almost one quarter of Australian jump horses race only once. There were ten horse fatalities in races over the study period, with an overall fatality rate of 5.1 fatalities per 1000 horses starting in a jump race (0.51%. There was significant disparity between the fatality rate for hurdles, 0.75 fatalities per 1000 starts (0.075% and steeplechases, 14 fatalities per 1000 starts (1.4%. Safety initiatives introduced by regulators in 2010 appear to have significantly decreased risks to horses in hurdles but have had little or no effect in steeplechases. Our discussion considers these Animals 2015, 5 1073 data in light of public controversy, political debate, and industry regulation related to jump horse safety.

  2. Jump Horse Safety: Reconciling Public Debate and Australian Thoroughbred Jump Racing Data, 2012-2014.

    Science.gov (United States)

    Ruse, Karen; Davison, Aidan; Bridle, Kerry

    2015-10-22

    Thoroughbred jump racing sits in the spotlight of contemporary welfare and ethical debates about horse racing. In Australia, jump racing comprises hurdle and steeplechase races and has ceased in all but two states, Victoria and South Australia. This paper documents the size, geography, composition, and dynamics of Australian jump racing for the 2012, 2013, and 2014 seasons with a focus on debate about risks to horses. We found that the majority of Australian jump racing is regional, based in Victoria, and involves a small group of experienced trainers and jockeys. Australian jump horses are on average 6.4 years of age. The jump career of the majority of horses involves participating in three or less hurdle races and over one season. Almost one quarter of Australian jump horses race only once. There were ten horse fatalities in races over the study period, with an overall fatality rate of 5.1 fatalities per 1000 horses starting in a jump race (0.51%). There was significant disparity between the fatality rate for hurdles, 0.75 fatalities per 1000 starts (0.075%) and steeplechases, 14 fatalities per 1000 starts (1.4%). Safety initiatives introduced by regulators in 2010 appear to have significantly decreased risks to horses in hurdles but have had little or no effect in steeplechases. Our discussion considers these Animals 2015, 5 1073 data in light of public controversy, political debate, and industry regulation related to jump horse safety.

  3. Jump spillover between oil prices and exchange rates

    Science.gov (United States)

    Li, Xiao-Ping; Zhou, Chun-Yang; Wu, Chong-Feng

    2017-11-01

    In this paper, we investigate the jump spillover effects between oil prices and exchange rates. To identify the latent historical jumps for exchange rates and oil prices, we use a Bayesian MCMC approach to estimate the stochastic volatility model with correlated jumps in both returns and volatilities for each. We examine the simultaneous jump intensities and the conditional jump spillover probabilities between oil prices and exchange rates, finding strong evidence of jump spillover effects. Further analysis shows that the jump spillovers are mainly due to exogenous events such as financial crises and geopolitical events. Thus, the findings have important implications for financial risk management.

  4. A multiplicity jump trigger using silicon planes

    International Nuclear Information System (INIS)

    Alexopoulos, T.; Erwin, A.R.

    1993-01-01

    Since silicon tracking planes are already present in a B decay experiment, it is an attractive idea to use these as part of a multiplicity jump detector. Two average B decays would produce a multiplicity jump of around 10 in the final state. Such a trigger has been tried for a fixed target Charm experiment with disappointing success. The failure was attributed to the difficulty in adequately controlling the gains of a large number of microstrip amplifies

  5. Portfolio Selection with Jumps under Regime Switching

    Directory of Open Access Journals (Sweden)

    Lin Zhao

    2010-01-01

    Full Text Available We investigate a continuous-time version of the mean-variance portfolio selection model with jumps under regime switching. The portfolio selection is proposed and analyzed for a market consisting of one bank account and multiple stocks. The random regime switching is assumed to be independent of the underlying Brownian motion and jump processes. A Markov chain modulated diffusion formulation is employed to model the problem.

  6. Jumps in binomial AR(1) processes

    OpenAIRE

    Weiß , Christian H.

    2009-01-01

    Abstract We consider the binomial AR(1) model for serially dependent processes of binomial counts. After a review of its definition and known properties, we investigate marginal and serial properties of jumps in such processes. Based on these results, we propose the jumps control chart for monitoring a binomial AR(1) process. We show how to evaluate the performance of this control chart and give design recommendations. correspondance: Tel.: +49 931 31 84968; ...

  7. Tests for nonrandomness in quantum jumps

    International Nuclear Information System (INIS)

    Berkeland, D.J.; Raymondson, D.A.; Tassin, V.M.

    2004-01-01

    In a fundamental test of quantum mechanics, we have observed 228 000 quantum jumps of a single trapped and laser cooled 88 Sr + ion. This represents a statistical increase of two orders of magnitude over previous similar analyses of quantum jumps. Compared to other searches for nonrandomness in quantum-mechanical processes, using quantum jumps simplifies the interpretation of data by eliminated multiparticle effects and providing near-unit detection efficiency of transitions. We measure the fractional reduction in the entropy of information to be -4 when the value of any interval between quantum jumps is known. We also find that the number of runs of successively increasing or decreasing interval times agrees with the theoretically expected values. Furthermore, we analyze 238 000 quantum jumps from two simultaneously confined ions and find that the number of apparently coincidental transitions is as expected. Finally, we observe 8400 spontaneous decays of two simultaneously trapped ions and find that the number of apparently coincidental decays from the metastable state agrees with the expected value. We find no evidence for short- or long-term correlations in the intervals of the quantum jumps or in the decay of the quantum states, in agreement with quantum theory

  8. Hydrodynamics of vertical jumping in Archer fish

    Science.gov (United States)

    Techet, Alexandra H.; Mendelson, Leah

    2017-11-01

    Vertical jumping for aerial prey from an aquatic environment requires both propulsive power and precise aim to succeed. Rapid acceleration to a ballistic velocity sufficient for reaching the prey height occurs before the fish leaves the water completely and experiences a thousandfold drop in force-producing ability. In addition to speed, accuracy and stability are crucial for successful feeding by jumping. This talk examines the physics of jumping using the archer fish as a model. Better known for their spitting abilities, archer fish will jump multiple body lengths out of the water for prey capture, from a stationary position just below the free surface. Modulation of oscillatory body kinematics and use of multiple fins for force production are identified as methods through which the fish can meet requirements for both acceleration and stabilization in limited space. Quantitative 3D PIV wake measurements reveal how variations in tail kinematics relate to thrust production throughout the course of a jumping maneuver and over a range of jump heights. By performing measurements in 3D, the timing, interactions, and relative contributions to thrust and lateral forces from each fin can be evaluated, elucidating the complex hydrodynamics that enable archer fish water exit.

  9. knock characteristics analysis of a supercharged spark ignition

    African Journals Online (AJOL)

    user

    The power output of a spark ignition engine could be improved by boosting the ... that the presence of aromatics was responsible for the better anti-knock ..... System, a Master's Thesis in the Institutionen för ... Maintenance and Reliability, Vol.

  10. William Knocke receives 2008 Virginia Outstanding Civil Engineer Award

    OpenAIRE

    Daniilidi, Christina

    2008-01-01

    William R. Knocke, W.C. English Professor and head of the Charles E. Via, Jr. Department of Civil and Environmental Engineering at Virginia Tech, was awarded the 2008 Virginia Outstanding Civil Engineer Award at the Virginia Section of the American Society of Civil Engineers' (ASCE) banquet, held recently in Williamsburg, Va.

  11. Knock Prediction Using a Simple Model for Ignition Delay

    KAUST Repository

    Kalghatgi, Gautam; Morganti, Kai; Algunaibet, Ibrahim; Sarathy, Mani; Dibble, Robert W.

    2016-01-01

    An earlier paper has shown the ability to predict the phasing of knock onset in a gasoline PFI engine using a simple ignition delay equation for an appropriate surrogate fuel made up of toluene and PRF (TPRF). The applicability of this approach

  12. Knock Prediction Using a Simple Model for Ignition Delay

    KAUST Repository

    Kalghatgi, Gautam

    2016-04-05

    An earlier paper has shown the ability to predict the phasing of knock onset in a gasoline PFI engine using a simple ignition delay equation for an appropriate surrogate fuel made up of toluene and PRF (TPRF). The applicability of this approach is confirmed in this paper in a different engine using five different fuels of differing RON, sensitivity, and composition - including ethanol blends. An Arrhenius type equation with a pressure correction for ignition delay can be found from interpolation of previously published data for any gasoline if its RON and sensitivity are known. Then, if the pressure and temperature in the unburned gas can be estimated or measured, the Livengood-Wu integral can be estimated as a function of crank angle to predict the occurrence of knock. Experiments in a single cylinder DISI engine over a wide operating range confirm that this simple approach can predict knock very accurately. The data presented should enable engineers to study knock or other auto-ignition phenomena e.g. in premixed compression ignition (PCI) engines without explicit chemical kinetic calculations. © Copyright 2016 SAE International.

  13. Semi-étale groupoids and applications

    DEFF Research Database (Denmark)

    Thomsen, Klaus

    2010-01-01

    We associate a C * -algebra to a locally compact Hausdorff groupoid with the property that the range map is locally injective. The construction generalizes J. Renault’s reduced groupoid C * -algebra of an étale groupoid and has the advantage that it works for the groupoid arising from a locally i...

  14. Tales of evaluation in school mathematics

    DEFF Research Database (Denmark)

    Andrade-Molina, Melissa

    2017-01-01

    This is the tale of the power effects of evaluation in the shaping of the desired child. It maps, by using historical and cultural strategies, the circulating truths about standardized assessments, about the need for learning mathematics, and about the axiomatization of space. The analysis takes ...

  15. "Clockwork": Philip Pullman's Posthuman Fairy Tale

    Science.gov (United States)

    Gooding, Richard

    2011-01-01

    This article examines the connections between posthumanism and narrative form in Philip Pullman's "Clockwork." Beginning with an account of Pullman's materialism, it argues that the novel represents consciousness and agency as emergent properties of matter, a position that manifests itself first in the tale's figurative language and later in the…

  16. Law as a Tale of Identity

    DEFF Research Database (Denmark)

    Schaumburg-Müller, Sten

    2010-01-01

    Understanding law as a tale of identity, indentity includes what we ought as much as what we are. Criticism of law and literature of seing literature as having precende over law which is a mere technicality. Different human rights consceptions in Denmark compared to Europe equal diffent identities....

  17. Performance analysis of jump-gliding locomotion for miniature robotics.

    Science.gov (United States)

    Vidyasagar, A; Zufferey, Jean-Christohphe; Floreano, Dario; Kovač, M

    2015-03-26

    Recent work suggests that jumping locomotion in combination with a gliding phase can be used as an effective mobility principle in robotics. Compared to pure jumping without a gliding phase, the potential benefits of hybrid jump-gliding locomotion includes the ability to extend the distance travelled and reduce the potentially damaging impact forces upon landing. This publication evaluates the performance of jump-gliding locomotion and provides models for the analysis of the relevant dynamics of flight. It also defines a jump-gliding envelope that encompasses the range that can be achieved with jump-gliding robots and that can be used to evaluate the performance and improvement potential of jump-gliding robots. We present first a planar dynamic model and then a simplified closed form model, which allow for quantification of the distance travelled and the impact energy on landing. In order to validate the prediction of these models, we validate the model with experiments using a novel jump-gliding robot, named the 'EPFL jump-glider'. It has a mass of 16.5 g and is able to perform jumps from elevated positions, perform steered gliding flight, land safely and traverse on the ground by repetitive jumping. The experiments indicate that the developed jump-gliding model fits very well with the measured flight data using the EPFL jump-glider, confirming the benefits of jump-gliding locomotion to mobile robotics. The jump-glide envelope considerations indicate that the EPFL jump-glider, when traversing from a 2 m height, reaches 74.3% of optimal jump-gliding distance compared to pure jumping without a gliding phase which only reaches 33.4% of the optimal jump-gliding distance. Methods of further improving flight performance based on the models and inspiration from biological systems are presented providing mechanical design pathways to future jump-gliding robot designs.

  18. Jump Horse Safety: Reconciling Public Debate and Australian Thoroughbred Jump Racing Data, 2012–2014

    Science.gov (United States)

    Ruse, Karen; Davison, Aidan; Bridle, Kerry

    2015-01-01

    Simple Summary This paper documents the dynamics of Australian thoroughbred jump racing in the 2012, 2013, and 2014 seasons with the aim of informing debate about risks to horses and the future of this activity. We conclude that the safety of Australian jump racing has improved in recent years but that steeplechases are considerably riskier for horses than hurdle races. Abstract Thoroughbred jump racing sits in the spotlight of contemporary welfare and ethical debates about horse racing. In Australia, jump racing comprises hurdle and steeplechase races and has ceased in all but two states, Victoria and South Australia. This paper documents the size, geography, composition, and dynamics of Australian jump racing for the 2012, 2013, and 2014 seasons with a focus on debate about risks to horses. We found that the majority of Australian jump racing is regional, based in Victoria, and involves a small group of experienced trainers and jockeys. Australian jump horses are on average 6.4 years of age. The jump career of the majority of horses involves participating in three or less hurdle races and over one season. Almost one quarter of Australian jump horses race only once. There were ten horse fatalities in races over the study period, with an overall fatality rate of 5.1 fatalities per 1000 horses starting in a jump race (0.51%). There was significant disparity between the fatality rate for hurdles, 0.75 fatalities per 1000 starts (0.075%) and steeplechases, 14 fatalities per 1000 starts (1.4%). Safety initiatives introduced by regulators in 2010 appear to have significantly decreased risks to horses in hurdles but have had little or no effect in steeplechases. Our discussion considers these data in light of public controversy, political debate, and industry regulation related to jump horse safety. PMID:26506396

  19. Activation of silenced cytokine gene promoters by the synergistic effect of TBP-TALE and VP64-TALE activators.

    Science.gov (United States)

    Anthony, Kim; More, Abhijit; Zhang, Xiaoliu

    2014-01-01

    Recent work has shown that the combinatorial use of multiple TALE activators can selectively activate certain cellular genes in inaccessible chromatin regions. In this study, we aimed to interrogate the activation potential of TALEs upon transcriptionally silenced immune genes in the context of non-immune cells. We designed a unique strategy, in which a single TALE fused to the TATA-box binding protein (TBP-TALE) is coupled with multiple VP64-TALE activators. We found that our strategy is significantly more potent than multiple TALE activators alone in activating expression of IL-2 and GM-CSF in diverse cell origins in which both genes are otherwise completely silenced. Chromatin analysis revealed that the gene activation was due in part to displacement of a distinctly positioned nucleosome. These studies provide a novel epigenetic mechanism for artificial gene induction and have important implications for targeted cancer immunotherapy, DNA vaccine development, as well as rational design of TALE activators.

  20. Jumping to conclusions in schizophrenia

    Directory of Open Access Journals (Sweden)

    Evans SL

    2015-07-01

    Full Text Available Simon L Evans,1 Bruno B Averbeck,2 Nicholas Furl31School of Psychology, University of Sussex, Brighton, East Sussex, UK; 2Laboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA; 3Department of Psychology, Royal Holloway, University of London, Egham, Surrey, UKAbstract: Schizophrenia is a mental disorder associated with a variety of symptoms, including hallucinations, delusions, social withdrawal, and cognitive dysfunction. Impairments on decision-making tasks are routinely reported: evidence points to a particular deficit in learning from and revising behavior following feedback. In addition, patients tend to make hasty decisions when probabilistic judgments are required. This is known as “jumping to conclusions” (JTC and has typically been demonstrated by presenting participants with colored beads drawn from one of two “urns” until they claim to be sure which urn the beads are being drawn from (the proportions of colors vary in each urn. Patients tend to make early decisions on this task, and there is evidence to suggest that a hasty decision-making style might be linked to delusion formation and thus be of clinical relevance. Various accounts have been proposed regarding what underlies this behavior. In this review, we briefly introduce the disorder and the decision-making deficits associated with it. We then explore the evidence for each account of JTC in the context of a wider decision-making deficit and then go on to summarize work exploring JTC in healthy controls using pharmacological manipulations and functional imaging. Finally, we assess whether JTC might have a role in therapy.Keywords: ketamine, decision making, delusions, fMRI, urn task

  1. Theoretical analysis of knock-out release of fission products from nuclear fuels

    International Nuclear Information System (INIS)

    Yamagishi, S.

    1975-01-01

    The knock-out release of fission products is studied theoretically. The general equations of knock-out release are derived, assuming that a fission fragment passing through the surface of nuclear fuels knocks out a local region of the surface with an effective thickness and an effective cross-sectional area. Using these equations, the knock-out release of fission gases is calculated for various cases. The conditions under which the knock-out coefficients (the average number of uranium atoms knocked out by one fission fragment) is obtainable are clarified by experiments on the knock-out release of fission gases. A method of determining the effective thickness and the effective cross-sectional area of a knock-out region is proposed. (Auth.)

  2. The reliability of vertical jump tests between the Vertec and My Jump phone application.

    Science.gov (United States)

    Yingling, Vanessa R; Castro, Dimitri A; Duong, Justin T; Malpartida, Fiorella J; Usher, Justin R; O, Jenny

    2018-01-01

    The vertical jump is used to estimate sports performance capabilities and physical fitness in children, elderly, non-athletic and injured individuals. Different jump techniques and measurement tools are available to assess vertical jump height and peak power; however, their use is limited by access to laboratory settings, excessive cost and/or time constraints thus making these tools oftentimes unsuitable for field assessment. A popular field test uses the Vertec and the Sargent vertical jump with countermovement; however, new low cost, easy to use tools are becoming available, including the My Jump iOS mobile application (app). The purpose of this study was to assess the reliability of the My Jump relative to values obtained by the Vertec for the Sargent stand and reach vertical jump (VJ) test. One hundred and thirty-five healthy participants aged 18-39 years (94 males, 41 females) completed three maximal Sargent VJ with countermovement that were simultaneously measured using the Vertec and the My Jump . Jump heights were quantified for each jump and peak power was calculated using the Sayers equation. Four separate ICC estimates and their 95% confidence intervals were used to assess reliability. Two analyses (with jump height and calculated peak power as the dependent variables, respectively) were based on a single rater, consistency, two-way mixed-effects model, while two others (with jump height and calculated peak power as the dependent variables, respectively) were based on a single rater, absolute agreement, two-way mixed-effects model. Moderate to excellent reliability relative to the degree of consistency between the Vertec and My Jump values was found for jump height (ICC = 0.813; 95% CI [0.747-0.863]) and calculated peak power (ICC = 0.926; 95% CI [0.897-0.947]). However, poor to good reliability relative to absolute agreement for VJ height (ICC = 0.665; 95% CI [0.050-0.859]) and poor to excellent reliability relative to absolute agreement for peak power

  3. Jump locations of jump-diffusion processes with state-dependent rates

    International Nuclear Information System (INIS)

    Miles, Christopher E; Keener, James P

    2017-01-01

    We propose a general framework for studying statistics of jump-diffusion systems driven by both Brownian noise (diffusion) and a jump process with state-dependent intensity. Of particular natural interest in many physical systems are the jump locations: the system evaluated at the jump times. As an example, this could be the voltage at which a neuron fires, or the so-called ‘threshold voltage’. However, the state-dependence of the jump rate provides direct coupling between the diffusion and jump components, making it difficult to disentangle the two to study individually. In this work, we provide an iterative map formulation of the sequence of distributions of jump locations. The distributions computed by this map can be used to elucidate other interesting quantities about the process, including statistics of the interjump times. Ultimately, the limit of the map reveals that knowledge of the stationary distribution of the full process is sufficient to recover (but not necessarily equal to) the distribution of jump locations. We propose two biophysical examples to illustrate the use of this framework to provide insight about a system. We find that a sharp threshold voltage emerges robustly in a simple stochastic integrate-and-fire neuronal model. The interplay between the two sources of noise is also investigated in a stepping model of molecular motor in intracellular transport pulling a diffusive cargo. (paper)

  4. Experimental study of the hydraulic jump in a hydraulic jump in a ...

    African Journals Online (AJOL)

    The hydraulic jump in a sloped rectangular channel is theoretically and experimentally examined. The study aims to determine the effect of the channel's slope on the sequent depth ratio of the jump. A theoretical relation is proposed for the inflow Froude number as function of the sequent depth ratio and the channel slope.

  5. Drop jumping. II. The influence of dropping height on the biomechanics of drop jumping

    NARCIS (Netherlands)

    Bobbert, M F; Huijing, P A; van Ingen Schenau, G J

    In the literature, athletes preparing for explosive activities are recommended to include drop jumping in their training programs. For the execution of drop jumps, different techniques and different dropping heights can be used. This study was designed to investigate for the performance of bounce

  6. Increase in Jumping Height Associated with Maximal Effort Vertical Depth Jumps.

    Science.gov (United States)

    Bedi, John F.; And Others

    1987-01-01

    In order to assess if there existed a statistically significant increase in jumping performance when dropping from different heights, 32 males, aged 19 to 26, performed a series of maximal effort vertical jumps after dropping from eight heights onto a force plate. Results are analyzed. (Author/MT)

  7. The effect of wind on jumping distance in ski jumping--fairness assessed.

    Science.gov (United States)

    Virmavirta, Mikko; Kivekäs, Juha

    2012-09-01

    The special wind compensation system recently adopted by Fédération Internationale de Ski (FIS; International Ski Federation) to consider the effects of changing wind conditions has caused some controversy. Here, the effect of wind on jumping distance in ski jumping was studied by means of computer simulation and compared with the wind compensation factors used by FIS during the World Cup season 2009/2010. The results showed clearly that the effect of increasing head/tail wind on jumping distance is not linear: +17.4 m/-29.1 m, respectively, for a wind speed of 3 m/s. The linear formula used in the trial period of the wind compensation system was found to be appropriate only for a limited range of jumping distances as the gradient of the landing slope slows down the rate of distance change in long jumps.

  8. A method of estimating the knock rating of hydrocarbon fuel blend

    Science.gov (United States)

    Sanders, Newell D

    1943-01-01

    The usefulness of the knock ratings of pure hydrocarbon compounds would be increased if some reliable method of calculating the knock ratings of fuel blends was known. The purpose of this study was to investigate the possibility of developing a method of predicting the knock ratings of fuel blends.

  9. Ionization in the Knock Zone of an Internal-combustion Engine

    Science.gov (United States)

    Hasting, Charles E

    1940-01-01

    The ionization in the knock zone of an internal-combustion engine was investigated. A suspected correlation between the intensity of knock and the degree of ionization was verified and an oscillation in the degree of ionization corresponding in frequency to the knock vibrations in the cylinder pressure was observed.

  10. Filtering and control of stochastic jump hybrid systems

    CERN Document Server

    Yao, Xiuming; Zheng, Wei Xing

    2016-01-01

    This book presents recent research work on stochastic jump hybrid systems. Specifically, the considered stochastic jump hybrid systems include Markovian jump Ito stochastic systems, Markovian jump linear-parameter-varying (LPV) systems, Markovian jump singular systems, Markovian jump two-dimensional (2-D) systems, and Markovian jump repeated scalar nonlinear systems. Some sufficient conditions are first established respectively for the stability and performances of those kinds of stochastic jump hybrid systems in terms of solution of linear matrix inequalities (LMIs). Based on the derived analysis conditions, the filtering and control problems are addressed. The book presents up-to-date research developments and novel methodologies on stochastic jump hybrid systems. The contents can be divided into two parts: the first part is focused on robust filter design problem, while the second part is put the emphasis on robust control problem. These methodologies provide a framework for stability and performance analy...

  11. Determinants of the abilities to jump higher and shorten the contact time in a running 1-legged vertical jump in basketball.

    Science.gov (United States)

    Miura, Ken; Yamamoto, Masayoshi; Tamaki, Hiroyuki; Zushi, Koji

    2010-01-01

    This study was conducted to obtain useful information for developing training techniques for the running 1-legged vertical jump in basketball (lay-up shot jump). The ability to perform the lay-up shot jump and various basic jumps was measured by testing 19 male basketball players. The basic jumps consisted of the 1-legged repeated rebound jump, the 2-legged repeated rebound jump, and the countermovement jump. Jumping height, contact time, and jumping index (jumping height/contact time) were measured and calculated using a contact mat/computer system that recorded the contact and air times. The jumping index indicates power. No significant correlation existed between the jumping height and contact time of the lay-up shot jump, the 2 components of the lay-up shot jump index. As a result, jumping height and contact time were found to be mutually independent abilities. The relationships in contact time between the lay-up shot jump to the 1-legged repeated rebound jump and the 2-legged repeated rebound jump were correlated on the same significance levels (p jumping height existed between the 1-legged repeated rebound jump and the lay-up shot jump (p jumping height between the lay-up shot jump and both the 2-legged repeated rebound jump and countermovement jump. The lay-up shot index correlated more strongly to the 1-legged repeated rebound jump index (p jump index (p jump is effective in improving both contact time and jumping height in the lay-up shot jump.

  12. Temperature jump boundary conditions in radiation diffusion

    International Nuclear Information System (INIS)

    Alonso, C.T.

    1976-12-01

    The radiation diffusion approximation greatly simplifies radiation transport problems. Yet the application of this method has often been unnecessarily restricted to optically thick regions, or has been extended through the use of such ad hoc devices as flux limiters. The purpose of this paper is to review and draw attention to the use of the more physically appropriate temperature jump boundary conditions for extending the range of validity of the diffusion approximation. Pioneering work has shown that temperature jump boundary conditions remove the singularity in flux that occurs in ordinary diffusion at small optical thicknesses. In this review paper Deissler's equations for frequency-dependent jump boundary conditions are presented and specific geometric examples are calculated analytically for steady state radiation transfer. When jump boundary conditions are applied to radiation diffusion, they yield exact solutions which are naturally flux- limited and geometry-corrected. We believe that the presence of temperature jumps on source boundaries is probably responsible in some cases for the past need for imposing ad hoc flux-limiting constraints on pure diffusion solutions. The solution for transfer between plane slabs, which is exact to all orders of optical thickness, also provides a useful tool for studying the accuracy of computer codes

  13. Scaling the viscous circular hydraulic jump

    Science.gov (United States)

    Argentina, Mederic; Cerda, Enrique; Duchesne, Alexis; Limat, Laurent

    2017-11-01

    The formation mechanism of hydraulic jumps has been proposed by Belanger in 1828 and rationalised by Lord Rayleigh in 1914. As the Froude number becomes higher than one, the flow super criticality induces an instability which yields the emergence of a steep structure at the fluid surface. Strongly deformed liquid-air interface can be observed as a jet of viscous fluid impinges a flat boundary at high enough velocity. In this experimental setup, the location of the jump depends on the viscosity of the liquid, as shown by T. Bohr et al. in 1997. In 2014, A. Duchesne et al. have established the constancy of the Froude number at jump. Hence, it remains a contradiction, in which the radial hydraulic jump location might be explained through inviscid theory, but is also viscosity dependent. We present a model based on the 2011 Rojas et al. PRL, which solves this paradox. The agreement with experimental measurements is excellent not only for the prediction of the position of the hydraulic jump, but also for the determination of the fluid thickness profile. We predict theoretically the critical value of the Froude number, which matches perfectly to that measured by Duchesne et al. We acknowledge the support of the CNRS and the Universit Cte d'Azur, through the IDEX funding.

  14. A locust-inspired miniature jumping robot.

    Science.gov (United States)

    Zaitsev, Valentin; Gvirsman, Omer; Ben Hanan, Uri; Weiss, Avi; Ayali, Amir; Kosa, Gabor

    2015-11-25

    Unmanned ground vehicles are mostly wheeled, tracked, or legged. These locomotion mechanisms have a limited ability to traverse rough terrain and obstacles that are higher than the robot's center of mass. In order to improve the mobility of small robots it is necessary to expand the variety of their motion gaits. Jumping is one of nature's solutions to the challenge of mobility in difficult terrain. The desert locust is the model for the presented bio-inspired design of a jumping mechanism for a small mobile robot. The basic mechanism is similar to that of the semilunar process in the hind legs of the locust, and is based on the cocking of a torsional spring by wrapping a tendon-like wire around the shaft of a miniature motor. In this study we present the jumping mechanism design, and the manufacturing and performance analysis of two demonstrator prototypes. The most advanced jumping robot demonstrator is power autonomous, weighs 23 gr, and is capable of jumping to a height of 3.35 m, covering a distance of 1.37 m.

  15. Biomechanics of stair walking and jumping.

    Science.gov (United States)

    Loy, D J; Voloshin, A S

    1991-01-01

    Physical activities such as stair walking and jumping result in increased dynamic loading on the human musculoskeletal system. Use of light weight, externally attached accelerometers allows for in-vivo monitoring of the shock waves invading the human musculoskeletal system during those activities. Shock waves were measured in four subjects performing stair walking up and down, jumping in place and jumping off a fixed elevation. The results obtained show that walking down a staircase induced shock waves with amplitude of 130% of that observed in walking up stairs and 250% of the shock waves experienced in level gait. The jumping test revealed levels of the shock waves nearly eight times higher than that in level walking. It was also shown that the shock waves invading the human musculoskeletal system may be generated not only by the heel strike, but also by the metatarsal strike. To moderate the risk of degenerative joint disorders four types of viscoelastic insoles were utilized to reduce the impact generated shock waves. The insoles investigated were able to reduce the amplitude of the shock wave by between 9% and 41% depending on the insole type and particular physical activity. The insoles were more effective in the reduction of the heel strike impacts than in the reduction of the metatarsal strike impacts. In all instances, the shock attenuation capacities of the insoles tested were greater in the jumping trials than in the stair walking studies. The insoles were ranked in three groups on the basis of their shock absorbing capacity.

  16. Directed evolution of the TALE N-terminal domain for recognition of all 5′ bases

    Science.gov (United States)

    Lamb, Brian M.; Mercer, Andrew C.; Barbas, Carlos F.

    2013-01-01

    Transcription activator-like effector (TALE) proteins can be designed to bind virtually any DNA sequence. General guidelines for design of TALE DNA-binding domains suggest that the 5′-most base of the DNA sequence bound by the TALE (the N0 base) should be a thymine. We quantified the N0 requirement by analysis of the activities of TALE transcription factors (TALE-TF), TALE recombinases (TALE-R) and TALE nucleases (TALENs) with each DNA base at this position. In the absence of a 5′ T, we observed decreases in TALE activity up to >1000-fold in TALE-TF activity, up to 100-fold in TALE-R activity and up to 10-fold reduction in TALEN activity compared with target sequences containing a 5′ T. To develop TALE architectures that recognize all possible N0 bases, we used structure-guided library design coupled with TALE-R activity selections to evolve novel TALE N-terminal domains to accommodate any N0 base. A G-selective domain and broadly reactive domains were isolated and characterized. The engineered TALE domains selected in the TALE-R format demonstrated modularity and were active in TALE-TF and TALEN architectures. Evolved N-terminal domains provide effective and unconstrained TALE-based targeting of any DNA sequence as TALE binding proteins and designer enzymes. PMID:23980031

  17. Directed evolution of the TALE N-terminal domain for recognition of all 5' bases.

    Science.gov (United States)

    Lamb, Brian M; Mercer, Andrew C; Barbas, Carlos F

    2013-11-01

    Transcription activator-like effector (TALE) proteins can be designed to bind virtually any DNA sequence. General guidelines for design of TALE DNA-binding domains suggest that the 5'-most base of the DNA sequence bound by the TALE (the N0 base) should be a thymine. We quantified the N0 requirement by analysis of the activities of TALE transcription factors (TALE-TF), TALE recombinases (TALE-R) and TALE nucleases (TALENs) with each DNA base at this position. In the absence of a 5' T, we observed decreases in TALE activity up to >1000-fold in TALE-TF activity, up to 100-fold in TALE-R activity and up to 10-fold reduction in TALEN activity compared with target sequences containing a 5' T. To develop TALE architectures that recognize all possible N0 bases, we used structure-guided library design coupled with TALE-R activity selections to evolve novel TALE N-terminal domains to accommodate any N0 base. A G-selective domain and broadly reactive domains were isolated and characterized. The engineered TALE domains selected in the TALE-R format demonstrated modularity and were active in TALE-TF and TALEN architectures. Evolved N-terminal domains provide effective and unconstrained TALE-based targeting of any DNA sequence as TALE binding proteins and designer enzymes.

  18. Evaluation of Knock Behavior for Natural Gas - Gasoline Blends in a Light Duty Spark Ignited Engine

    Energy Technology Data Exchange (ETDEWEB)

    Pamminger, Michael [Argonne National Lab. (ANL), Argonne, IL (United States); Sevik, James [Argonne National Lab. (ANL), Argonne, IL (United States); Scarcelli, Riccardo [Argonne National Lab. (ANL), Argonne, IL (United States); Wallner, Thomas [Argonne National Lab. (ANL), Argonne, IL (United States); Wooldridge, Steven [Ford Motor Co., Detroit, MI (United States); Boyer, Brad [Ford Motor Co., Detroit, MI (United States); Hall, Carrie M. [Illinois Inst. of Technology, Chicago, IL (United States)

    2016-10-17

    The compression ratio is a strong lever to increase the efficiency of an internal combustion engine. However, among others, it is limited by the knock resistance of the fuel used. Natural gas shows a higher knock resistance compared to gasoline, which makes it very attractive for use in internal combustion engines. The current paper describes the knock behavior of two gasoline fuels, and specific incylinder blend ratios with one of the gasoline fuels and natural gas. The engine used for these investigations is a single cylinder research engine for light duty application which is equipped with two separate fuel systems. Both fuels can be used simultaneously which allows for gasoline to be injected into the intake port and natural gas to be injected directly into the cylinder to overcome the power density loss usually connected with port fuel injection of natural gas. Adding natural gas at wide open throttle helps to reduce knock mitigating measures and increases the efficiency and power density compared to the other gasoline type fuels with lower knock resistance. The used methods, knock intensity and number of pressure waves, do not show significant differences in knock behavior for the natural gas - gasoline blends compared to the gasoline type fuels. A knock integral was used to describe the knock onset location of the fuels tested. Two different approaches were used to determine the experimental knock onset and were compared to the knock onset delivered by the knock integral (chemical knock onset). The gasoline type fuels show good agreement between chemical and experimental knock onset. However, the natural gas -gasoline blends show higher discrepancies comparing chemical and experimental knock onset.

  19. TALE proteins search DNA using a rotationally decoupled mechanism.

    Science.gov (United States)

    Cuculis, Luke; Abil, Zhanar; Zhao, Huimin; Schroeder, Charles M

    2016-10-01

    Transcription activator-like effector (TALE) proteins are a class of programmable DNA-binding proteins used extensively for gene editing. Despite recent progress, however, little is known about their sequence search mechanism. Here, we use single-molecule experiments to study TALE search along DNA. Our results show that TALEs utilize a rotationally decoupled mechanism for nonspecific search, despite remaining associated with DNA templates during the search process. Our results suggest that the protein helical structure enables TALEs to adopt a loosely wrapped conformation around DNA templates during nonspecific search, facilitating rapid one-dimensional (1D) diffusion under a range of solution conditions. Furthermore, this model is consistent with a previously reported two-state mechanism for TALE search that allows these proteins to overcome the search speed-stability paradox. Taken together, our results suggest that TALE search is unique among the broad class of sequence-specific DNA-binding proteins and supports efficient 1D search along DNA.

  20. Rapid and accurate synthesis of TALE genes from synthetic oligonucleotides.

    Science.gov (United States)

    Wang, Fenghua; Zhang, Hefei; Gao, Jingxia; Chen, Fengjiao; Chen, Sijie; Zhang, Cuizhen; Peng, Gang

    2016-01-01

    Custom synthesis of transcription activator-like effector (TALE) genes has relied upon plasmid libraries of pre-fabricated TALE-repeat monomers or oligomers. Here we describe a novel synthesis method that directly incorporates annealed synthetic oligonucleotides into the TALE-repeat units. Our approach utilizes iterative sets of oligonucleotides and a translational frame check strategy to ensure the high efficiency and accuracy of TALE-gene synthesis. TALE arrays of more than 20 repeats can be constructed, and the majority of the synthesized constructs have perfect sequences. In addition, this novel oligonucleotide-based method can readily accommodate design changes to the TALE repeats. We demonstrated an increased gene targeting efficiency against a genomic site containing a potentially methylated cytosine by incorporating non-conventional repeat variable di-residue (RVD) sequences.

  1. Teaching the "A" Level Text: "The Wife of Bath's Prologue and Tale."

    Science.gov (United States)

    Spraggs, Gillian

    1988-01-01

    Presents an approach for teaching Chaucer's "Wife of Bath's Prologue and Tale" (from "The Canterbury Tales"). Recommends several reference texts related to the "The Canterbury Tales" and medieval literature in general. (MM)

  2. Serious ski jumping injuries in Norway.

    Science.gov (United States)

    Wester, K

    1985-01-01

    Injuries caused by ski jumping have been poorly investigated. Among approximately 2,200 licensed jumpers in Norway, there occurred at least 12 injuries with a permanent medical disability of greater than or equal to 10%. The risk of being seriously injured is approximately 5% in a 5 year period (1977 to 1981); it is higher in the age group 15 to 17 years. Seven injuries were very serious [four central nervous system (CNS) lesions, two leg amputations, and one blindness of one eye], and five were less serious (sequelae to fractures of the lower extremities). The first jump of the day is particularly dangerous, and so is the beginning and end of the season. It seems dangerous to use more than one standard heel block. Poor preparation of the jump may have contributed to the accidents. Based on the findings, several prophylactic measures are suggested.

  3. Telling business stories as fellowship-tales

    DEFF Research Database (Denmark)

    Smith, Robert; Neergaard, Helle

    2015-01-01

    Purpose – This paper aims to explore the “Fellowship-Tale” as an alternative tale type for narrating entrepreneur stories. The authors illustrate this by telling the Pilgrim business story. It is common for the deeds of men who founded businesses to be narrated as heroic entrepreneur stories...... – The research indicates that “fellowship-tales” provide a viable and credible alternative to the fairy-tale rendition common in entrepreneur and business stories. Research limitations/implications – An obvious limitation is that one merely swaps one narrative framework for another, albeit it offers dissenting...... voices a real choice. Practical implications – This study has the potential to be far reaching because at a practical level, it allows disengaged entrepreneurs and significant others the freedom to exercise their individual and collective voices within a framework of nested stories. Originality...

  4. How Good are Fairy Tales for Adults?

    Directory of Open Access Journals (Sweden)

    Nives Ličen

    1998-12-01

    Full Text Available Children and adults can learn together in family. Their living together is a valuable experience. Family life can be made agreeable and instructive not only as a result of extensive knowledge, displaying mostly a rational dimension, but also due to emotional inteligence, attitudes and values. Fairy tales can be an incentive for personal development of both children and adults. To adults they offer an opportunity to get to know themselves better, to understand better their thoughts, values, environment. On the other hand, they help them formulate messages they would like to pass on their children. Fairy tales are one of the possible contents for the time family members spend togehter. Moreover, they are a source of entertainment, laughing and they create an excellent atmosphere for good family relationships.

  5. Single proton knock-out from 24F

    International Nuclear Information System (INIS)

    Thoennessen, M.; Baumann, T.; Brown, B.A.; Enders, J.; Frank, N.H.; Hansen, P.G.; Heckman, P.; Luther, B.A.; Seitz, J.P.; Stolz, A.; Tryggestad, E.

    2004-01-01

    The measurement of the single proton knock-out reaction from 24 F on a 12 C target at 46.7 MeV/nucleon yielded a 23 O ground state population of (6.6+/-1.0) mb. The data were compared to calculations based on the many-body shell model and the eikonal theory. The results are consistent with a [0d5/26]-bar 1s1/2 configuration of 23 O

  6. DJ-1 KNOCK-DOWN IMPAIRS ASTROCYTE MITOCHONDRIAL FUNCTION

    Science.gov (United States)

    LARSEN, N. J.; AMBROSI, G.; MULLETT, S. J.; BERMAN, S. B.; HINKLE, D. A.

    2012-01-01

    Mitochondrial dysfunction has long been implicated in the pathogenesis of Parkinson’s disease (PD). PD brain tissues show evidence for mitochondrial respiratory chain Complex I deficiency. Pharmacological inhibitors of Complex I, such as rotenone, cause experimental parkinsonism. The cytoprotective protein DJ-1, whose deletion is sufficient to cause genetic PD, is also known to have mitochondria-stabilizing properties. We have previously shown that DJ-1 is over-expressed in PD astrocytes, and that DJ-1 deficiency impairs the capacity of astrocytes to protect co-cultured neurons against rotenone. Since DJ-1 modulated, astrocyte-mediated neuroprotection against rotenone may depend upon proper astrocytic mitochondrial functioning, we hypothesized that DJ-1 deficiency would impair astrocyte mitochondrial motility, fission/fusion dynamics, membrane potential maintenance, and respiration, both at baseline and as an enhancement of rotenone-induced mitochondrial dysfunction. In astrocyte-enriched cultures, we observed that DJ-1 knock-down reduced mitochondrial motility primarily in the cellular processes of both untreated and rotenone treated cells. In these same cultures, DJ-1 knock-down did not appreciably affect mitochondrial fission, fusion, or respiration, but did enhance rotenone-induced reductions in the mitochondrial membrane potential. In neuron–astrocyte co-cultures, astrocytic DJ-1 knock-down reduced astrocyte process mitochondrial motility in untreated cells, but this effect was not maintained in the presence of rotenone. In the same co-cultures, astrocytic DJ-1 knock-down significantly reduced mitochondrial fusion in the astrocyte cell bodies, but not the processes, under the same conditions of rotenone treatment in which DJ-1 deficiency is known to impair astrocyte-mediated neuroprotection. Our studies therefore demonstrated the following new findings: (i) DJ-1 deficiency can impair astrocyte mitochondrial physiology at multiple levels, (ii) astrocyte

  7. Recent Advancements in Lightning Jump Algorithm Work

    Science.gov (United States)

    Schultz, Christopher J.; Petersen, Walter A.; Carey, Lawrence D.

    2010-01-01

    In the past year, the primary objectives were to show the usefulness of total lightning as compared to traditional cloud-to-ground (CG) networks, test the lightning jump algorithm configurations in other regions of the country, increase the number of thunderstorms within our thunderstorm database, and to pinpoint environments that could prove difficult for any lightning jump configuration. A total of 561 thunderstorms have been examined in the past year (409 non-severe, 152 severe) from four regions of the country (North Alabama, Washington D.C., High Plains of CO/KS, and Oklahoma). Results continue to indicate that the 2 lightning jump algorithm configuration holds the most promise in terms of prospective operational lightning jump algorithms, with a probability of detection (POD) at 81%, a false alarm rate (FAR) of 45%, a critical success index (CSI) of 49% and a Heidke Skill Score (HSS) of 0.66. The second best performing algorithm configuration was the Threshold 4 algorithm, which had a POD of 72%, FAR of 51%, a CSI of 41% and an HSS of 0.58. Because a more complex algorithm configuration shows the most promise in terms of prospective operational lightning jump algorithms, accurate thunderstorm cell tracking work must be undertaken to track lightning trends on an individual thunderstorm basis over time. While these numbers for the 2 configuration are impressive, the algorithm does have its weaknesses. Specifically, low-topped and tropical cyclone thunderstorm environments are present issues for the 2 lightning jump algorithm, because of the suppressed vertical depth impact on overall flash counts (i.e., a relative dearth in lightning). For example, in a sample of 120 thunderstorms from northern Alabama that contained 72 missed events by the 2 algorithm 36% of the misses were associated with these two environments (17 storms).

  8. The last half-repeat of transcription activator-like effector (TALE) is dispensable and thereby TALE-based technology can be simplified.

    Science.gov (United States)

    Zheng, Chong-Ke; Wang, Chun-Lian; Zhang, Xiao-Ping; Wang, Fu-Jun; Qin, Teng-Fei; Zhao, Kai-Jun

    2014-09-01

    To activate the expression of host genes that contribute to pathogen growth, pathogenic Xanthomonas bacteria inject their transcription activator-like effectors (TALEs) into plant cells and the TALEs bind to target gene promoters by the central repeat region consisting of near-perfect 34-amino-acid repeats (34-aa repeats). Based on the recognition codes between the 34-aa repeats and the targeted nucleotides, TALE-based technologies, such as designer TALEs (dTALEs) and TALE nucleases (TALENs), have been developed. Amazingly, every natural TALE invariantly has a truncated last half-repeat (LHR) at the end of the 34-aa repeats. Consequently, all the reported dTALEs and TALENs also harbour their LHRs. Here, we show that the LHRs in dTALEs are dispensable for the function of gene activation by both transient expression assays in Nicotiana benthamiana and gene-specific targeting in the rice genome, indicating that TALEs might originate from a single progenitor. In the light of this finding, we demonstrate that dTALEs can be constructed through two simple steps. Moreover, the activation strengths of dTALEs lacking the LHR are comparable with those of dTALEs harbouring the LHR. Our results provide new insights into the origin of natural TALEs, and will facilitate the simplification of the design and assembly of TALE-based tools, such as dTALEs and TALENs, in the near future. © 2014 BSPP AND JOHN WILEY & SONS LTD.

  9. Validity of a Jump Mat for assessing Countermovement Jump Performance in Elite Rugby Players.

    Science.gov (United States)

    Dobbin, Nick; Hunwicks, Richard; Highton, Jamie; Twist, Craig

    2017-02-01

    This study determined the validity of the Just Jump System ® (JJS) for measuring flight time, jump height and peak power output (PPO) in elite rugby league players. 37 elite rugby league players performed 6 countermovement jumps (CMJ; 3 with and 3 without arms) on a jump mat and force platform. A sub-sample (n=28) was used to cross-validate the equations for flight time, jump height and PPO. The JJS systematically overestimated flight time and jump height compared to the force platform (Pjump height ( with R 2 =0.945; without R 2 =0.987). Our equations revealed no systematic difference between corrected and force platform scores and an improved the agreement for flight time (Ratio limits of agreement: with 1.00 vs. 1.36; without 1.00 vs. 1.16) and jump height ( with 1.01 vs. 1.34; without 1.01 vs. 1.15), meaning that our equations can be used to correct JJS scores for elite rugby players. While our equation improved the estimation of PPO ( with 1.02; without 1.01) compared to existing equations (Harman: 1.20; Sayers: 1.04), this only accounted for 64 and 69% of PPO. © Georg Thieme Verlag KG Stuttgart · New York.

  10. CLIMATIC JUMP IN THE POLAR REGION (I)

    OpenAIRE

    ヤマモト, リョウザブロウ; イワシマ, タツヤ; ホシアイ, マコト; Ryozaburo, YAMAMOTO; Tatsuya, IWASHIMA; Makoto, HOSHIAI

    1987-01-01

    From the analysis of the climatic elements over Japan, we can detect the "climatic jumps" around the years 1920 and 1950,which is a new concept in the climatic diagnosis proposed by the present authors (R. YAMAMOTO et al. : J. Meteorol. Soc. Jpn., 63,1157,1985,64,273,1986). Taking account of several results which show the simultaneous occurrence of the climatic jumps of the surface air temperature, precipitation, etc., in the other regions by the other investigators, we may infer the "climati...

  11. Does trampoline or hard surface jumping influence lower extremity alignment?

    Science.gov (United States)

    Akasaka, Kiyokazu; Tamura, Akihiro; Katsuta, Aoi; Sagawa, Ayako; Otsudo, Takahiro; Okubo, Yu; Sawada, Yutaka; Hall, Toby

    2017-12-01

    [Purpose] To determine whether repetitive trampoline or hard surface jumping affects lower extremity alignment on jump landing. [Subjects and Methods] Twenty healthy females participated in this study. All subjects performed a drop vertical jump before and after repeated maximum effort trampoline or hard surface jumping. A three-dimensional motion analysis system and two force plates were used to record lower extremity angles, moments, and vertical ground reaction force during drop vertical jumps. [Results] Knee extensor moment after trampoline jumping was greater than that after hard surface jumping. There were no significant differences between trials in vertical ground reaction force and lower extremity joint angles following each form of exercise. Repeated jumping on a trampoline increased peak vertical ground reaction force, hip extensor, knee extensor moments, and hip adduction angle, while decreasing hip flexion angle during drop vertical jumps. In contrast, repeated jumping on a hard surface increased peak vertical ground reaction force, ankle dorsiflexion angle, and hip extensor moment during drop vertical jumps. [Conclusion] Repeated jumping on the trampoline compared to jumping on a hard surface has different effects on lower limb kinetics and kinematics. Knowledge of these effects may be useful in designing exercise programs for different clinical presentations.

  12. Test-retest reliability of jump execution variables using mechanography: a comparison of jump protocols.

    Science.gov (United States)

    Fitzgerald, John S; Johnson, LuAnn; Tomkinson, Grant; Stein, Jesse; Roemmich, James N

    2018-05-01

    Mechanography during the vertical jump may enhance screening and determining mechanistic causes underlying physical performance changes. Utility of jump mechanography for evaluation is limited by scant test-retest reliability data on force-time variables. This study examined the test-retest reliability of eight jump execution variables assessed from mechanography. Thirty-two women (mean±SD: age 20.8 ± 1.3 yr) and 16 men (age 22.1 ± 1.9 yr) attended a familiarization session and two testing sessions, all one week apart. Participants performed two variations of the squat jump with squat depth self-selected and controlled using a goniometer to 80º knee flexion. Test-retest reliability was quantified as the systematic error (using effect size between jumps), random error (using coefficients of variation), and test-retest correlations (using intra-class correlation coefficients). Overall, jump execution variables demonstrated acceptable reliability, evidenced by small systematic errors (mean±95%CI: 0.2 ± 0.07), moderate random errors (mean±95%CI: 17.8 ± 3.7%), and very strong test-retest correlations (range: 0.73-0.97). Differences in random errors between controlled and self-selected protocols were negligible (mean±95%CI: 1.3 ± 2.3%). Jump execution variables demonstrated acceptable reliability, with no meaningful differences between the controlled and self-selected jump protocols. To simplify testing, a self-selected jump protocol can be used to assess force-time variables with negligible impact on measurement error.

  13. THE STRUCTURE OF POEM IN TALE KERINCI FOLKLORE

    Directory of Open Access Journals (Sweden)

    - Nazurty

    2015-06-01

    Full Text Available Tale is the folklore in the form of poem that is sung. This study aims to gain in-depth understanding of the structure of Tale poem in the release of the Kerinci pilgrims. This qualitative study employed content analysis as the method with a structural approach. This study discussed the structure of the Tale poem. The results of the study are Tale poem consists of sampiran phrase, the rhyme/ sound phrase, and content. It composed by ten lines to twenty lines. It has ab ab rhyme according to the sound phrase flanking each line. The sound expression serves as rhyme and rhythm former.

  14. Morality's ugly implications in Oscar Wilde's fairy tales.

    Science.gov (United States)

    Jones, Justin T

    2011-01-01

    In Oscar Wilde's two volumes of fairy tales, "The Happy Prince" and Other Tales (1888) and A House of Pomegranates (1891), many central characters meet with premature death or physical disfigurement after learning a bourgeois moral lesson. In an attempt to explain this unconventional phenomenon in the fairy tale tradition, this essay examines Wilde's stories through the lens of his aesthetic ideology and demonstrates how the superficial morality of the Victorian bourgeoisie corrodes each tale's aesthetic integrity, causing the characters to either deny morality outright, assume the guise of Christian philanthropy, or die as the result of their moral reformation.

  15. Influence of Knee-to-Feet Jump Training on Vertical Jump and Hang Clean Performance.

    Science.gov (United States)

    Stark, Laura; Pickett, Karla; Bird, Michael; King, Adam C

    2016-11-01

    Stark, L, Pickett, K, Bird, M, and King, AC. Influence of knee-to-feet jump training on vertical jump and hang clean performance. J Strength Cond Res 30(11): 3084-3089, 2016-From a motor learning perspective, the practice/training environment can result in positive, negative, or neutral transfer to the testing conditions. The purpose of this study was to examine the training effect of a novel movement (knee-to-feet [K2F] jumps) and whether a 6-week training program induced a positive transfer effect to other power-related movements (vertical jump and hang clean [HC]). Twenty-six intercollegiate athletes from power-emphasized sports were paired and counter-balanced into a control (i.e., maintained their respective sport-specific lifting regimen) or an experimental group (i.e., completed a 6-week progressive training program of K2F jumps in addition to respective lifting regimen). A pre- and posttest design was used to investigate the effect of training on K2F jump height and transfer effect to vertical jump height (VJH) and 2-repetition maximum (RM) HC performance. A significant increase in K2F jump height was found for the experimental group. Vertical jump height significantly increased from pre- to posttest but no group or interaction (group × time) effect was found, and there were nonsignificant differences for HC. Posttest data showed significant correlations between all pairs of the selected exercises with the highest correlation between K2F jump height and VJ H (R = 0.40) followed by VJH and 2RM HC (R = 0.38) and 2RM HC and K2F jump height (R = 0.23). The results suggest that K2F jump training induced the desired learning effect but was specific to the movement in that no effect of transfer occurred to the other power-related movements. This finding is value for strength and condition professionals who design training programs to enhance athletic performance.

  16. Filtering of a Markov Jump Process with Counting Observations

    International Nuclear Information System (INIS)

    Ceci, C.; Gerardi, A.

    2000-01-01

    This paper concerns the filtering of an R d -valued Markov pure jump process when only the total number of jumps are observed. Strong and weak uniqueness for the solutions of the filtering equations are discussed

  17. Jumping on the Social Media Bandwagon

    Science.gov (United States)

    Blakeslee, Lori

    2012-01-01

    Should a school district jump on the social media bandwagon? Yes! Social media provide a low-cost way to communicate school district priorities, influence decision makers, and tell its story without filters. Equally important, social media are where constituents are spending a lot of their time. With more than 800 million members, Facebook is an…

  18. Jump as Far as You Can [Problem Solvers: Problem

    Science.gov (United States)

    Bofferding, Laura; Yigit, Melike

    2013-01-01

    The standing long jump was an Olympic event until 1912. In 1904, Ray Ewry set the world record for the longest standing long jump, which was about 11.5 feet, or 138 inches. Although the standing long jump is no longer an Olympic event, the Norwegians still include it in their National Competition, and Arne Tvervaag set a new world record at about…

  19. Thomson's Jumping Ring over a Long Coil

    Science.gov (United States)

    Jeffery, Rondo N.; Amiri, Farhang

    2018-01-01

    The classic jumping ring apparatus consists of a coil with an iron core that extends out of the coil. A copper or aluminum ring placed over the iron core jumps upward when AC power is applied to the coil. In this paper we will examine a modified design of the jumping ring apparatus, called the "long-coil design." It allows the ring to…

  20. Vorticity determination in a hydraulic jump by application of method ...

    African Journals Online (AJOL)

    The method of characteristics for solving systems of partial differential equations coupled with jump conditions is used in analysing flow downstream of a hydraulic jump instead of the normal analytical approach adopted in Hornung [1]. It is shown that the method of characteristics together with the jump conditions can ...

  1. Scaling and jumping: Gravity loses grip on small jumpers

    NARCIS (Netherlands)

    Scholz, M.N.; Bobbert, M.F.; van Soest, A.J.

    2006-01-01

    There are several ways to quantify jumping performance, a common definition being the height gained by the body's centre of mass (CM) in the airborne phase. Under this definition, jump height is determined by take-off velocity. According to the existing literature on jumping and scaling, take-off

  2. Effect of early training on the jumping technique of horses

    NARCIS (Netherlands)

    Santamaría, Susana; Bobbert, Maarten F.; Back, Willem; Barneveld, Ab; van Weeren, P. Rene

    Objective - To investigate the effects of early training for jumping by comparing the jumping technique of horses that had received early training with that of horses raised conventionally. Animals - 40 Dutch Warmblood horses. Procedure - The horses were analyzed kinematically during free jumping at

  3. Deriving appropriate boundary conditions, and accelerating position-jump simulations, of diffusion using non-local jumping

    International Nuclear Information System (INIS)

    Taylor, P R; Baker, R E; Yates, C A

    2015-01-01

    In this paper we explore lattice-based position-jump models of diffusion, and the implications of introducing non-local jumping; particles can jump to a range of nearby boxes rather than only to their nearest neighbours. We begin by deriving conditions for equivalence with traditional local jumping models in the continuum limit. We then generalize a previously postulated implementation of the Robin boundary condition for a non-local process of arbitrary maximum jump length, and present a novel implementation of flux boundary conditions, again generalized for a non-local process of arbitrary maximum jump length. In both these cases we validate our results using stochastic simulation. We then proceed to consider two variations on the basic diffusion model: a hybrid local/non-local scheme suitable for models involving sharp concentration gradients, and the implementation of biased jumping. In all cases we show that non-local jumping can deliver substantial time savings for stochastic simulations. (paper)

  4. Computational singular perturbation analysis of super-knock in SI engines

    KAUST Repository

    Jaasim, Mohammed

    2018-04-02

    Pre-ignition engine cycles leading to super-knock were simulated with a 48 species skeletal iso-octane mechanism to identify the dominant reaction pathways that are present in super-knock. To mimic pre-ignition, a deflagration front was generated via a hot spot that is placed over the piston at close proximity to the end-wall. Computational singular perturbation (CSP) was used to analyze the chemical dynamics at various in-cylinder locations: a point at the center of the cylinder where the deflagration front consumes the air/fuel mixture and two points located at 3 mm from the end-wall where super-knock and mild knock occur. The CSP analysis of the point at the center of the cylinder reveals weak two-stage ignition-like dynamics with a short second stage. At the other points, a pronounced two-stage ignition is displayed with a long second stage. A distinct contribution of formaldehyde (CHO) at the second stage of ignition that adds to fast explosive modes in the super-knock points is not observed in the point at the center. A comparison between knock and super-knock analysis indicates that a similar set of reactions is responsible for the abnormal behavior but the fast explosive time scales are comparatively slower for knock, indicating lower reactivity, which results in the reduced intensity of knock. The analyzed results decoded important reactions responsible for the occurrence of super-knock.

  5. The Encoding of Subjectivity in Chaucer's "The Wife of Bath's Tale" and "The Pardoner's Tale"

    DEFF Research Database (Denmark)

    Klitgård, Ebbe

    2011-01-01

    This chapter discusses Chaucer's narrative technique in two of The Canterbury Tales and argues that the narrative voice is Chaucer's, and that the subjectivity of the Wife of Bath and the Pardoner should be approached in different ways than through theories of the novel....

  6. Contemporary Christian Tale for Children: Questions of Poetics and Problems

    Directory of Open Access Journals (Sweden)

    Inna V. Shchepacheva

    2017-09-01

    Full Text Available The article deals with the problems and poetics of Christian fairy tale for children in contemporary Russian literature. The relevance of this issue is motivated by a number of polemic, problematic statements about the form and the content of Christian literature in general, and children's literature in particular. The research reveals features of Christian children’s literature, gives characteristics of its genres and defines the place of the fairy tale as a genre that most satisfies young readers’ needs. The central theme of Christian fairy tales is the theme of realization of existence of God, distinction of good and evil, understanding of sin and punishment. This problem-thematic complex is embodied mainly at the level of composition and character system of fairy tales. During analysis two types of Christian fairy tales are distinguished, generally based on the folklore canon of the fairy tales about animals. In the first type main characters are animals and they help people magically. The predominant didacticism of fairy tales of the first type is realized in schematization of animal images and absence of plot development. The peculiarity of the second type is based on traditional cyclical adventure story and absence of open characters’ convention which is a common feature to parable-allegorical fairy tales.

  7. TALE factors poise promoters for activation by Hox proteins.

    Science.gov (United States)

    Choe, Seong-Kyu; Ladam, Franck; Sagerström, Charles G

    2014-01-27

    Hox proteins form complexes with TALE cofactors from the Pbx and Prep/Meis families to control transcription, but it remains unclear how Hox:TALE complexes function. Examining a Hoxb1b:TALE complex that regulates zebrafish hoxb1a transcription, we find maternally deposited TALE proteins at the hoxb1a promoter already during blastula stages. These TALE factors recruit histone-modifying enzymes to promote an active chromatin profile at the hoxb1a promoter and also recruit RNA polymerase II (RNAPII) and P-TEFb. However, in the presence of TALE factors, RNAPII remains phosphorylated on serine 5 and hoxb1a transcription is inefficient. By gastrula stages, Hoxb1b binds together with TALE factors to the hoxb1a promoter. This triggers P-TEFb-mediated transitioning of RNAPII to the serine 2-phosphorylated form and efficient hoxb1a transcription. We conclude that TALE factors access promoters during early embryogenesis to poise them for activation but that Hox proteins are required to trigger efficient transcription. Copyright © 2014 Elsevier Inc. All rights reserved.

  8. The Indecisive Feminist: Study of Anne Sexton's Revisionist Fairy Tales

    Science.gov (United States)

    Mohammed, Nadia Fayidh

    2015-01-01

    Fairy tales to female writers are major resource for their abundant writings, but for the feminist poets since 1960s, they become essential subject matter to often deal with in their literary production. With the motivation to address the conventional tradition of patriarchal society, and re-address the stereotype females inhabiting these tales,…

  9. Genre Transformation of the Fairy Tale in Contemporary Russian Literature

    Directory of Open Access Journals (Sweden)

    Ekaterina Zueva

    2017-09-01

    Full Text Available This research is devoted to some peculiarities of structure and semantics of contemporary Russian fairy tale. The analyzed genre model is quite actual in the literature of modern turn of the centuries. It is actualized in the creativity of L. Petrushevskaya, A. Kabakov, B. Akunin, M. Fray, D. Bykov, etc. This is connected with the universality of themes and problems and the dynamics of structure of genre analyzed. Modern literature process suggests the use of various genre forms (including fairy-tale one in the context of realization of game strategies of world construction with the deconstruction principle domination. The usage of the most productive for such kind of research methods (structural-semantical and comparative ones gives grounds for understanding the specifics of realization of deconstruction principle through the variety of forms and meanings. For example, the scheme of “genre memory” is widely used in contemporary fairy tale. If that scheme deals with the sphere of semantics, then structural components are actively deconstructed (e.g. fairy tales by L. Petrushevskaya. If the meaningful fairy tale composition models are actualized, then the semantic component is widely transformed (e.g. Moscow Fairy Tales by A. Kabakov. The most important peculiarity of contemporary fairy tale is the integration of fairy tale, legendary, mythological and literary plots to the one game system. The result of this is on the one hand travestying of the iconic plots, on the other hand achieving the new meanings due to including context mechanisms.

  10. Knock-limited performance of several internal coolants

    Science.gov (United States)

    Bellman, Donald R; Evvard, John C

    1945-01-01

    The effect of internal cooling on the knock-limited performance of an-f-28 fuel was investigated in a CFR engine, and the following internal coolants were used: (1) water, (2), methyl alcohol-water mixture, (3) ammonia-methyl alcohol-water mixture, (4) monomethylamine-water mixture, (5) dimethylamine-water mixture, and (6) trimethylamine-water mixture. Tests were run at inlet-air temperatures of 150 degrees and 250 degrees F. to indicate the temperature sensitivity of the internal-coolant solutions.

  11. Caracterización del 'Knock out' en Boxeo

    OpenAIRE

    Pic-Aguilar, Miguel; Sánchez-López, Carmen R.; Blanco Villaseñor, Ángel

    2016-01-01

    El objetivo de este trabajo es identificar las cuatro últimas acciones motrices emitidas (golpes) por boxeadores campeones del mundo de los pesos pesados y así poder caracterizar el 'Knock out' en boxeo. Para ello, hemos desarrollado una herramienta de observación que consta de cuatro criterios y 35 categorías. Para la selección de la muestra se tuvo en cuenta dos requisitos: haberse proclamado campeón del mundo del peso pesado durante el período que comprende 1921-2007 (desde Jack Dempsey ha...

  12. Option Valuation with Observable Volatility and Jump Dynamics

    DEFF Research Database (Denmark)

    Christoffersen, Peter; Feunoua, Bruno; Jeon, Yoontae

    Under very general conditions, the total quadratic variation of a jump-diffusion process can be decomposed into diffusive volatility and squared jump variation. We use this result to develop a new option valuation model in which the underlying asset price exhibits volatility and jump intensity...... dynamics. The volatility and jump intensity dynamics in the model are directly driven by model-free empirical measures of diffusive volatility and jump variation. Because the empirical measures are observed in discrete intervals, our option valuation model is cast in discrete time, allowing...

  13. Option Valuation with Observable Volatility and Jump Dynamics

    DEFF Research Database (Denmark)

    Christoffersen, Peter; Feunoua, Bruno; Jeon, Yoontae

    2015-01-01

    Under very general conditions, the total quadratic variation of a jump-diffusion process can be decomposed into diffusive volatility and squared jump variation. We use this result to develop a new option valuation model in which the underlying asset price exhibits volatility and jump intensity...... dynamics. The volatility and jump intensity dynamics in the model are directly driven by model-free empirical measures of diffusive volatility and jump variation. Because the empirical measures are observed in discrete intervals, our option valuation model is cast in discrete time, allowing...

  14. DESIGN OF A FAST CHROMATICITY JUMP IN RHIC

    International Nuclear Information System (INIS)

    MONTAG, C.; KEWISCH, J.; BRUNO, D.; GANETIS, G.; LOUIE, W.

    2003-01-01

    During transition crossing in the .Relativistic Heavy Ion Collider (RHIC), chromaticities have to change sign. This sign change is partially accomplished by the γ t quadrupole jump; however, the resulting chromaticity jump is only Δξ x = 2.1 in the horizontal and Δξ y = 2.4 in the vertical plane. To increase the jump height, a dedicated chromaticity jump scheme has been designed, consisting of fast power supplies connected to six sextupoles per ring, which is capable of providing a chromaticity jump of Δξ = 6

  15. TALE-mediated modulation of transcriptional enhancers in vivo.

    Science.gov (United States)

    Crocker, Justin; Stern, David L

    2013-08-01

    We tested whether transcription activator-like effectors (TALEs) could mediate repression and activation of endogenous enhancers in the Drosophila genome. TALE repressors (TALERs) targeting each of the five even-skipped (eve) stripe enhancers generated repression specifically of the focal stripes. TALE activators (TALEAs) targeting the eve promoter or enhancers caused increased expression primarily in cells normally activated by the promoter or targeted enhancer, respectively. This effect supports the view that repression acts in a dominant fashion on transcriptional activators and that the activity state of an enhancer influences TALE binding or the ability of the VP16 domain to enhance transcription. In these assays, the Hairy repression domain did not exhibit previously described long-range transcriptional repression activity. The phenotypic effects of TALER and TALEA expression in larvae and adults are consistent with the observed modulations of eve expression. TALEs thus provide a novel tool for detection and functional modulation of transcriptional enhancers in their native genomic context.

  16. [Development of a Japanese version of the TALE scale].

    Science.gov (United States)

    Ochiai, Tsutomu; Oguchi, Takashi

    2013-12-01

    The Thinking About Life Experiences (TALE) Scale (Bluck & Alea, 2011) has three subscales that assess the self, social, and directive functions of autobiographical memory. This study constructs a Japanese version of the TALE Scale and examines its reliability and validity. Fifteen items that assess the three functions of autobiographical memory were translated into Japanese. We conducted an online investigation with 600 men and women between 20-59 years of age. In Study 1, exploratory and confirmatory factor analysis identified that the three-factor structure of the Japanese version of the TALE Scale was the same as the original TALE Scale. Sufficient internal consistency of the scale was found, and the construct validity of the scale was supported by correlation analysis. Study 2 confirmed that the test-retest reliabilities of the three subscales were sufficient. Thus, this Japanese version of the TALE Scale is useful to assess autobiographical memory functions in Japan.

  17. Elliptic Tales Curves, Counting, and Number Theory

    CERN Document Server

    Ash, Avner

    2012-01-01

    Elliptic Tales describes the latest developments in number theory by looking at one of the most exciting unsolved problems in contemporary mathematics--the Birch and Swinnerton-Dyer Conjecture. The Clay Mathematics Institute is offering a prize of 1 million to anyone who can discover a general solution to the problem. In this book, Avner Ash and Robert Gross guide readers through the mathematics they need to understand this captivating problem. The key to the conjecture lies in elliptic curves, which are cubic equations in two variables. These equations may appear simple, yet they arise from

  18. Biomechanical Analysis of the Jump Shot in Basketball

    Directory of Open Access Journals (Sweden)

    Struzik Artur

    2014-10-01

    Full Text Available Basketball players usually score points during the game using the jump shot. For this reason, the jump shot is considered to be the most important element of technique in basketball and requires a high level of performance. The aim of this study was to compare the biomechanical characteristics of the lower limbs during a jump shot without the ball and a countermovement jump without an arm swing. The differences between variables provide information about the potential that an athlete can utilise during a game when performing a jump shot. The study was conducted among 20 second-league basketball players by means of a Kistler force plate and the BTS SMART system for motion analysis. The variables measured included the take-off time, mean power, peak power, relative mean power, jump height, maximum landing force and calculated impact ratio. Surprisingly, more advantageous variables were found for the jump shot. This finding suggests a very high performance level in the jump shot in the studied group and a maximum utilisation of their motor abilities. Both types of jumps were characterised by high mean and peak power values and average heights. The high forces at landing, which result in considerable impact ratios, may have prompted the studied group to land softly. Use of the countermovement jump without an arm swing is recommended to assess and predict the progression of player’s jumping ability

  19. Validity of Hip-worn Inertial Measurement Unit Compared to Jump Mat for Jump Height Measurement in Adolescents.

    Science.gov (United States)

    Rantalainen, T; Hesketh, K D; Rodda, C; Duckham, R L

    2018-06-16

    Jump tests assess lower body power production capacity, and can be used to evaluate athletic ability and development during growth. Wearable inertial measurement units (IMU) seem to offer a feasible alternative to laboratory-based equipment for jump height assessments. Concurrent validity of these devices for jump height assessments has only been established in adults. Therefore, the purpose of this study was to evaluate the concurrent validity of IMU-based jump height estimate compared to contact mat-based jump height estimate in adolescents. Ninety-five adolescents (10-13 years-of-age; girls N=41, height = 154 (SD 9) cm, weight = 44 (11) kg; boys N=54, height=156 (10) cm, weight = 46 (13) kg) completed three counter-movement jumps for maximal jump height on a contact mat. Inertial recordings (accelerations, rotations) were concurrently recorded with a hip-worn IMU (sampling at 256 Hz). Jump height was evaluated based on flight time. The mean IMU-derived jump height was 27.1 (SD 3.8) cm, and the corresponding mean jump-mat-derived value was 21.5 (3.4) cm. While a significant 26% mean difference was observed between the methods (5.5 [95% limits of agreement 2.2 to 8.9] cm, p = 0.006), the correspondence between methods was excellent (ICC = 0.89). The difference between methods was weakly positively associated with jump height (r = 0.28, P = 0.007). Take-off velocity derived jump height was also explored but produced only fair congruence. In conclusion, IMU-derived jump height exhibited excellent congruence to contact mat-based jump height and therefore presents a feasible alternative for jump height assessments in adolescents. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  20. A Jump Diffusion Model for Volatility and Duration

    DEFF Research Database (Denmark)

    Wei, Wei; Pelletier, Denis

    by the market microstructure theory. Traditional measures of volatility do not utilize durations. I adopt a jump diffusion process to model the persistence of intraday volatility and conditional duration, and their interdependence. The jump component is disentangled from the continuous part of the price......, volatility and conditional duration process. I develop a MCMC algorithm for the inference of irregularly spaced multivariate process with jumps. The algorithm provides smoothed estimates of the latent variables such as spot volatility, jump times and jump sizes. I apply this model to IBM data and I find...... meaningful relationship between volatility and conditional duration. Also, jumps play an important role in the total variation, but the jump variation is smaller than traditional measures that use returns sampled at lower frequency....

  1. Propulsion efficiency and imposed flow fields of a copepod jump

    DEFF Research Database (Denmark)

    Jiang, H.; Kiørboe, Thomas

    2011-01-01

    Pelagic copepods jump to relocate, to attack prey and to escape predators. However, there is a price to be paid for these jumps in terms of their energy costs and the hydrodynamic signals they generate to rheotactic predators. Using observed kinematics of various types of jumps, we computed...... the imposed flow fields and associated energetics of jumps by means of computational fluid dynamics simulations by modeling the copepod as a self-propelled body. The computational fluid dynamics simulation was validated by particle image velocimetry data. The flow field generated by a repositioning jump...... the flow structure. The flow field associated with an escape jump sequence also includes two dominant vortex structures: one leading wake vortex generated as a result of the first jump and one around the body, but between these two vortex structures is an elongated, long-lasting flow trail with flow...

  2. Prediction of knock limited operating conditions of a natural gas engine

    International Nuclear Information System (INIS)

    Soylu, Seref

    2005-01-01

    Computer models of engine processes are valuable tools for predicting and analyzing engine performance and allow exploration of many engine design alternatives in an inexpensive fashion. In the present work, a zero-dimensional, two zone thermodynamic model was used to determine the knock limited operating conditions of a natural gas engine. Experimentally based burning rate models were used for flame initiation and propagation calculations. A knock model was incorporated with the zero-dimensional model. Comparison of the measured and calculated cylinder pressure data indicated that the model is able to match the measured cylinder pressure data with less than 8% error in magnitudes if the computations are started at the experimental spark timing. The knock predictions agreed with the measurements also. With the established knock model, it is possible not only to investigate whether knock is observed with changing operating and design parameters, but also to evaluate their effects on the maximum possible knock intensity

  3. Source characteristics of the underwater knocking displays of a male Pacific walrus (Odobenus rosmarus divergens)

    DEFF Research Database (Denmark)

    Hughes, William R.; Reichmuth, Colleen; Mulsow, Jason L.

    2011-01-01

    "knocks"’ punctuated by occasional metallic "bells." The source characteristics of the knocking sounds that were regularly emitted by a male walrus raised in captivity were examined. Knocks were produced as single 20 ms pulses, or as doublets and triplets, and were typically repeated at rates of 0.8/s...... to 1.2/s. These were loud sounds with greater bandwidth than previously reported: mean source levels were 186 dB pk-pk re 1 Pa at 1 m (range 164-196) with maximum frequency >24 kHz. Production of each knock was associated with visible impulsive movement of the forehead. During rut, this walrus had...... difficulty inhibiting sound production and would often continue to emit knocks in air during haul-out and even while eating, suggesting an endogenous component to this behavior. A strong correlation between his seasonal testosterone levels and the persistence of knocking displays was confirmed. Captive...

  4. Knock down of the myostatin gene by RNA interference increased body weight in chicken.

    Science.gov (United States)

    Bhattacharya, T K; Shukla, R; Chatterjee, R N; Dushyanth, K

    2017-01-10

    Myostatin is a negative regulator of muscular growth in poultry and other animals. Of several approaches, knocking down the negative regulator is an important aspect to augment muscular growth in chicken. Knock down of myostatin gene has been performed by shRNA acting against the expression of gene in animals. Two methods of knock down of gene in chicken such as embryo manipulation and sperm mediated method have been performed. The hatching percentage in embryo manipulation and sperm mediated method of knock down was 58.0 and 41.5%, respectively. The shRNA in knock down chicken enhanced body weight at 6 weeks by 26.9%. The dressing percentage and serum biochemical parameters such as SGPT and alkaline phosphatase differed significantly (Pknock down and control birds. It is concluded that knocking down the myostatin gene successfully augmented growth in chicken. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. System and method for controlling engine knock using electro-hydraulic valve actuation

    Science.gov (United States)

    Brennan, Daniel G

    2013-12-10

    A control system for an engine includes a knock control module and a valve control module. The knock control module adjusts a period that one or more of an intake valve and an exhaust valve of a cylinder are open based on engine knock corresponding to the cylinder. The valve control module, based on the adjusted period, controls the one or more of the intake valve and the exhaust valve using one or more hydraulic actuators.

  6. Violence and the Daniel tales in a children's bible | Nel | HTS ...

    African Journals Online (AJOL)

    Children enjoy the tales of Daniel and his three friends, whether told in Sunday school, day school, by parents or grandparents. These tales are cast essentially in violent terms. In this article a specific version of the tales in a children's Bible is analysed to show in what way violence serves as the thread that holds the tales ...

  7. Gamma Transition Jump for PS2

    CERN Document Server

    Bartmann, W; Métral, E; Möhl, D; Peggs, S

    2008-01-01

    The PS2, which is proposed as a replacement for the existing ~50-year old PS accelerator, is presently considered to be a normal conducting synchrotron with an injection kinetic energy of 4 GeV and a maximum energy of 50 GeV. One of the possible lattices (FODO option) foresees crossing of transition energy near 10 GeV. Since the phase-slip-factor $\\eta$ becomes very small near transition energy, many intensity dependent effects can take place in both longitudinal and transverse planes. The aim of the present paper is on the one hand to scale the gamma transition jump, used since 1973 in the PS, to the projected PS2 and on the other hand based on these results the analysis of the implementation and feasibility of a gamma transition jump scheme in a conventional FODO lattice.

  8. Testing jumps via false discovery rate control.

    Science.gov (United States)

    Yen, Yu-Min

    2013-01-01

    Many recently developed nonparametric jump tests can be viewed as multiple hypothesis testing problems. For such multiple hypothesis tests, it is well known that controlling type I error often makes a large proportion of erroneous rejections, and such situation becomes even worse when the jump occurrence is a rare event. To obtain more reliable results, we aim to control the false discovery rate (FDR), an efficient compound error measure for erroneous rejections in multiple testing problems. We perform the test via the Barndorff-Nielsen and Shephard (BNS) test statistic, and control the FDR with the Benjamini and Hochberg (BH) procedure. We provide asymptotic results for the FDR control. From simulations, we examine relevant theoretical results and demonstrate the advantages of controlling the FDR. The hybrid approach is then applied to empirical analysis on two benchmark stock indices with high frequency data.

  9. Testing jumps via false discovery rate control.

    Directory of Open Access Journals (Sweden)

    Yu-Min Yen

    Full Text Available Many recently developed nonparametric jump tests can be viewed as multiple hypothesis testing problems. For such multiple hypothesis tests, it is well known that controlling type I error often makes a large proportion of erroneous rejections, and such situation becomes even worse when the jump occurrence is a rare event. To obtain more reliable results, we aim to control the false discovery rate (FDR, an efficient compound error measure for erroneous rejections in multiple testing problems. We perform the test via the Barndorff-Nielsen and Shephard (BNS test statistic, and control the FDR with the Benjamini and Hochberg (BH procedure. We provide asymptotic results for the FDR control. From simulations, we examine relevant theoretical results and demonstrate the advantages of controlling the FDR. The hybrid approach is then applied to empirical analysis on two benchmark stock indices with high frequency data.

  10. Entropy jump across an inviscid shock wave

    Science.gov (United States)

    Salas, Manuel D.; Iollo, Angelo

    1995-01-01

    The shock jump conditions for the Euler equations in their primitive form are derived by using generalized functions. The shock profiles for specific volume, speed, and pressure are shown to be the same, however density has a different shock profile. Careful study of the equations that govern the entropy shows that the inviscid entropy profile has a local maximum within the shock layer. We demonstrate that because of this phenomenon, the entropy, propagation equation cannot be used as a conservation law.

  11. Price jumps on European stock markets

    Czech Academy of Sciences Publication Activity Database

    Hanousek, Jan; Kočenda, Evžen; Novotný, Jan

    2014-01-01

    Roč. 14, č. 1 (2014), s. 10-22 ISSN 2214-8450 R&D Projects: GA ČR(CZ) GAP403/11/0020; GA ČR(CZ) GBP402/12/G097 Grant - others:UK(CZ) UNCE 204005/2012 Institutional support: PRVOUK-P23 Keywords : stock markets * price jump indicators * non-parametric testing Subject RIV: AH - Economics

  12. Development and evaluation of an efficient heterologous gene knock-in reporter system in Lactococcus lactis.

    Science.gov (United States)

    Lu, Yifei; Yan, Hongxiang; Deng, Jiezhong; Huang, Zhigang; Jin, Xurui; Yu, Yanlan; Hu, Qiwen; Hu, Fuquan; Wang, Jing

    2017-09-18

    Lactococcus lactis is a food grade probiotics and widely used to express heterologous proteins. Generally, target genes are knocked into the L. lactis genome through double-crossover recombination to express heterologous proteins stably. However, creating marker-less heterologous genes knocked-in clones is laborious. In this study, an efficient heterologous gene knock-in reporter system was developed in L. lactis NZ9000. Our knock-in reporter system consists of a temperature-sensitive plasmid pJW and a recombinant L. lactis strain named NZB. The pJW contains homologous arms, and was constructed to knock-in heterologous genes at a fixed locus of NZ9000 genome. lacZ (β-galactosidase) gene was knocked into the chromosome of NZ9000 as a counter-selective marker through the plasmid pJW to generate NZB. The engineered NZB strain formed blue colonies on X-Gal plate. The desired double-crossover mutants formed white colonies distinctive from the predominantly blue colonies (parental and plasmid-integrated clones) when the embedded lacZ was replaced with the target heterologous genes carried by pJW in NZB. By using the system, the heterologous gene knocked-in clones are screened by colony phenotype change rather than by checking colonies individually. Our new knock-in reporter system provides an efficient method to create heterologous genes knocked-in clones.

  13. Take-off aerodynamics in ski jumping.

    Science.gov (United States)

    Virmavirta, M; Kivekäs, J; Komi, P V

    2001-04-01

    The effect of aerodynamic forces on the force-time characteristics of the simulated ski jumping take-off was examined in a wind tunnel. Vertical and horizontal ground reaction forces were recorded with a force plate installed under the wind tunnel floor. The jumpers performed take-offs in non-wind conditions and in various wind conditions (21-33 m s(-1)). EMGs of the important take-off muscles were recorded from one jumper. The dramatic decrease in take-off time found in all jumpers can be considered as the result of the influence of aerodynamic lift. The loss in impulse due to the shorter force production time with the same take-off force is compensated with the increase in lift force, resulting in a higher vertical velocity (V(v)) than is expected from the conventional calculation of V(v) from the force impulse. The wind conditions emphasized the explosiveness of the ski jumping take-off. The aerodynamic lift and drag forces which characterize the aerodynamic quality of the initial take-off position (static in-run position) varied widely even between the examined elite ski jumpers. According to the computer simulation these differences can decisively affect jumping distance. The proper utilization of the prevailing aerodynamic forces before and during take-off is a very important prerequisite for achieving a good flight position.

  14. Hydraulic jumps in ''viscous'' accretion disks

    International Nuclear Information System (INIS)

    Michel, F.C.

    1984-01-01

    We propose that the dissipative process necessary for rapid accretion disk evolution is driven by hydraulic jump waves on the surface of the disk. These waves are excited by the asymmetric nature of the central rotator (e.g., neutron star magnetosphere) and spiral out into the disk to form a pattern corotating with the central object. Disk matter in turn is slowed slightly at each encounter with the jump and spirals inward. In this process, the disk is heated by true turbulence produced in the jumps. Additional effects, such as a systematic misalignment of the magnetic moment of the neutron star until it is nearly orthogonal, and systematic distortion of the magnetosphere in such a way as to form an even more asymmetric central ''paddle wheel'' may enhance the interaction with inflowing matter. The application to X-ray sources corresponds to the ''slow'' solutions of Ghosh and Lamb, and therefore to rms magnetic fields of about 4 x 10 10 gauss. Analogous phenomena have been proposed to act in the formation of galactic spiral structure

  15. Sex Differences in Countermovement Jump Phase Characteristics

    Directory of Open Access Journals (Sweden)

    John J. McMahon

    2017-01-01

    Full Text Available The countermovement jump (CMJ is commonly used to explore sex differences in neuromuscular function, but previous studies have only reported gross CMJ measures or have partly examined CMJ phase characteristics. The purpose of this study was to explore differences in CMJ phase characteristics between male and female athletes by comparing the force-, power-, velocity-, and displacement-time curves throughout the entire CMJ, in addition to gross measures. Fourteen men and fourteen women performed three CMJs on a force platform from which a range of kinetic and kinematic variables were calculated via forward dynamics. Jump height (JH, reactive strength index modified, relative peak concentric power, and eccentric and concentric displacement, velocity, and relative impulse were all greater for men (g = 0.58–1.79. Relative force-time curves were similar between sexes, but relative power-, velocity-, and displacement-time curves were greater for men at 90%–95% (immediately before and after peak power, 47%–54% (start of eccentric phase and 85%–100% (latter half of concentric phase, and 65%–87% (bottom of countermovement and initial concentric phase of normalized jump time, respectively. The CMJ distinguished between sexes, with men demonstrating greater JH through applying a larger concentric impulse and, thus, achieving greater velocity throughout most of the concentric phase, including take-off.

  16. Jump Squat is More Related to Sprinting and Jumping Abilities than Olympic Push Press.

    Science.gov (United States)

    Loturco, I; Kobal, R; Maldonado, T; Piazzi, A F; Bottino, A; Kitamura, K; Abad, C C C; Pereira, L A; Nakamura, F Y

    2017-07-01

    The aim of this study was to test the relationships between jump squat (JS) and Olympic push press (OPP) power outputs and performance in sprint, squat jump (SJ), countermovement jump (CMJ) and change of direction (COD) speed tests in elite soccer players. 27 athletes performed a maximum power load test to determine their bar mean propulsive power (MPP) and bar mean propulsive velocity (MPV) in the JS and OPP exercises. Magnitude-based inference was used to compare the exercises. The MPV was almost certainly higher in the OPP than in the JS. The MPP relative to body mass (MPP REL) was possibly higher in the OPP. Only the JS MPP REL presented very large correlations with linear speed ( r> 0.7, for speed in 5, 10, 20 and 30 m) and vertical jumping abilities ( r> 0.8, for SJ and CMJ), and moderate correlation with COD speed ( r= 0.45). Although significant (except for COD), the associations between OPP outcomes and field-based measurements (speed, SJ and CMJ) were all moderate, ranging from 0.40 to 0.48. In a group composed of elite soccer players, the JS exercise is more associated with jumping and sprinting abilities than the OPP. Longitudinal studies are needed to confirm if these strong relationships imply superior training effects in favor of the JS exercise. © Georg Thieme Verlag KG Stuttgart · New York.

  17. An efficient interpolation technique for jump proposals in reversible-jump Markov chain Monte Carlo calculations

    Science.gov (United States)

    Farr, W. M.; Mandel, I.; Stevens, D.

    2015-01-01

    Selection among alternative theoretical models given an observed dataset is an important challenge in many areas of physics and astronomy. Reversible-jump Markov chain Monte Carlo (RJMCMC) is an extremely powerful technique for performing Bayesian model selection, but it suffers from a fundamental difficulty and it requires jumps between model parameter spaces, but cannot efficiently explore both parameter spaces at once. Thus, a naive jump between parameter spaces is unlikely to be accepted in the Markov chain Monte Carlo (MCMC) algorithm and convergence is correspondingly slow. Here, we demonstrate an interpolation technique that uses samples from single-model MCMCs to propose intermodel jumps from an approximation to the single-model posterior of the target parameter space. The interpolation technique, based on a kD-tree data structure, is adaptive and efficient in modest dimensionality. We show that our technique leads to improved convergence over naive jumps in an RJMCMC, and compare it to other proposals in the literature to improve the convergence of RJMCMCs. We also demonstrate the use of the same interpolation technique as a way to construct efficient ‘global’ proposal distributions for single-model MCMCs without prior knowledge of the structure of the posterior distribution, and discuss improvements that permit the method to be used in higher dimensional spaces efficiently. PMID:26543580

  18. Force generation and temperature-jump and length-jump tension transients in muscle fibers.

    Science.gov (United States)

    Davis, J S; Rodgers, M E

    1995-01-01

    Muscle tension rises with increasing temperature. The kinetics that govern the tension rise of maximally Ca(2+)-activated, skinned rabbit psoas fibers over a temperature range of 0-30 degrees C was characterized in laser temperature-jump experiments. The kinetic response is simple and can be readily interpreted in terms of a basic three-step mechanism of contraction, which includes a temperature-sensitive rapid preequilibrium(a) linked to a temperature-insensitive rate-limiting step and followed by a temperature-sensitive tension-generating step. These data and mechanism are compared and contrasted with the more complex length-jump Huxley-Simmons phases in which all states that generate tension or bear tension are perturbed. The rate of the Huxley-Simmons phase 4 is temperature sensitive at low temperatures but plateaus at high temperatures, indicating a change in rate-limiting step from a temperature-sensitive (phase 4a) to a temperature-insensitive reaction (phase 4b); the latter appears to correlate with the slow, temperature-insensitive temperature-jump relaxation. Phase 3 is absent in the temperature-jump, which excludes it from tension generation. We confirm that de novo tension generation occurs as an order-disorder transition during phase 2slow and the equivalent, temperature-sensitive temperature-jump relaxation. PMID:7612845

  19. Do Bilateral Vertical Jumps With Reactive Jump Landings Achieve Osteogenic Thresholds With and Without Instruction in Premenopausal Women?

    Science.gov (United States)

    Clissold, Tracey L; Winwood, Paul W; Cronin, John B; De Souza, Mary Jane

    2018-04-01

    Jumps have been investigated as a stimulus for bone development; however, effects of instruction, jump type, and jump-landing techniques need investigation. This study sought to identify whether ground reaction forces (GRFs) for bilateral vertical jumps (countermovement jumps and drop jumps) with reactive jump-landings (ie, jumping immediately after initial jump-landing), with instruction and with instruction withdrawn, achieve magnitudes and rates of strain previously shown to improve bone mass among premenopausal women. Twenty-one women (Mean ± SD: 43.3 ± 5.9 y; 69.4 ± 9.6 kg; 167 ± 5.5 cm; 27.5 ± 8.7% body fat) performed a testing session 'with instruction' followed by a testing session performed 1 week later with 'instruction withdrawn.' The magnitudes (4.59 to 5.49 body weight [BW]) and rates of strain (263 to 359 BW·s -1 ) for the jump-landings, performed on an AMTI force plate, exceeded previously determined thresholds (>3 BWs and >43 BW·s -1 ). Interestingly, significantly larger peak resultant forces, (↑10%; P = .002) and peak rates of force development (↑20%; P jump-landing (postreactive jump). Small increases (ES = 0.22-0.42) in all landing forces were observed in the second jump-landing with 'instruction withdrawn.' These jumps represent a unique training stimulus for premenopausal women and achieve osteogenic thresholds thought prerequisite for bone growth.

  20. Quantitative analysis of TALE-DNA interactions suggests polarity effects.

    Science.gov (United States)

    Meckler, Joshua F; Bhakta, Mital S; Kim, Moon-Soo; Ovadia, Robert; Habrian, Chris H; Zykovich, Artem; Yu, Abigail; Lockwood, Sarah H; Morbitzer, Robert; Elsäesser, Janett; Lahaye, Thomas; Segal, David J; Baldwin, Enoch P

    2013-04-01

    Transcription activator-like effectors (TALEs) have revolutionized the field of genome engineering. We present here a systematic assessment of TALE DNA recognition, using quantitative electrophoretic mobility shift assays and reporter gene activation assays. Within TALE proteins, tandem 34-amino acid repeats recognize one base pair each and direct sequence-specific DNA binding through repeat variable di-residues (RVDs). We found that RVD choice can affect affinity by four orders of magnitude, with the relative RVD contribution in the order NG > HD ≈ NN > NI > NK. The NN repeat preferred the base G over A, whereas the NK repeat bound G with 10(3)-fold lower affinity. We compared AvrBs3, a naturally occurring TALE that recognizes its target using some atypical RVD-base combinations, with a designed TALE that precisely matches 'standard' RVDs with the target bases. This comparison revealed unexpected differences in sensitivity to substitutions of the invariant 5'-T. Another surprising observation was that base mismatches at the 5' end of the target site had more disruptive effects on affinity than those at the 3' end, particularly in designed TALEs. These results provide evidence that TALE-DNA recognition exhibits a hitherto un-described polarity effect, in which the N-terminal repeats contribute more to affinity than C-terminal ones.

  1. Jump Shrug Height and Landing Forces Across Various Loads.

    Science.gov (United States)

    Suchomel, Timothy J; Taber, Christopher B; Wright, Glenn A

    2016-01-01

    The purpose of this study was to examine the effect that load has on the mechanics of the jump shrug. Fifteen track and field and club/intramural athletes (age 21.7 ± 1.3 y, height 180.9 ± 6.6 cm, body mass 84.7 ± 13.2 kg, 1-repetition-maximum (1RM) hang power clean 109.1 ± 17.2 kg) performed repetitions of the jump shrug at 30%, 45%, 65%, and 80% of their 1RM hang power clean. Jump height, peak landing force, and potential energy of the system at jump-shrug apex were compared between loads using a series of 1-way repeated-measures ANOVAs. Statistical differences in jump height (P .05). The greatest magnitudes of jump height, peak landing force, and potential energy of the system at the apex of the jump shrug occurred at 30% 1RM hang power clean and decreased as the external load increased from 45% to 80% 1RM hang power clean. Relationships between peak landing force and potential energy of the system at jump-shrug apex indicate that the landing forces produced during the jump shrug may be due to the landing strategy used by the athletes, especially at lighter loads. Practitioners may prescribe heavier loads during the jump-shrug exercise without viewing landing force as a potential limitation.

  2. Jumping robots: a biomimetic solution to locomotion across rough terrain.

    Science.gov (United States)

    Armour, Rhodri; Paskins, Keith; Bowyer, Adrian; Vincent, Julian; Megill, William; Bomphrey, Richard

    2007-09-01

    This paper introduces jumping robots as a means to traverse rough terrain; such terrain can pose problems for traditional wheeled, tracked and legged designs. The diversity of jumping mechanisms found in nature is explored to support the theory that jumping is a desirable ability for a robot locomotion system to incorporate, and then the size-related constraints are determined from first principles. A series of existing jumping robots are presented and their performance summarized. The authors present two new biologically inspired jumping robots, Jollbot and Glumper, both of which incorporate additional locomotion techniques of rolling and gliding respectively. Jollbot consists of metal hoop springs forming a 300 mm diameter sphere, and when jumping it raises its centre of gravity by 0.22 m and clears a height of 0.18 m. Glumper is of octahedral shape, with four 'legs' that each comprise two 500 mm lengths of CFRP tube articulating around torsion spring 'knees'. It is able to raise its centre of gravity by 1.60 m and clears a height of 1.17 m. The jumping performance of the jumping robot designs presented is discussed and compared against some specialized jumping animals. Specific power output is thought to be the performance-limiting factor for a jumping robot, which requires the maximization of the amount of energy that can be stored together with a minimization of mass. It is demonstrated that this can be achieved through optimization and careful materials selection.

  3. Neuromuscular function during drop jumps in young and elderly males.

    Science.gov (United States)

    Piirainen, Jarmo M; Linnamo, Vesa; Sippola, Niina; Avela, Janne

    2012-12-01

    The Hoffman reflex (H-reflex), indicating alpha-motoneuron pool activity, has been shown to be task - and in resting conditions - age dependent. How aging affects H-reflex activity during explosive movements is not clear at present. The purpose of this study was to examine the effects of aging on H-reflexes during drop jumps, and its possible role in drop jump performance. Ten young (26.8 ± 2.7 years) and twenty elderly (64.2 ± 2.7 years) subjects participated in the study. Maximal drop jump performance and soleus H-reflex response (H/M jump) 20 ms after ground contact were measured in a sledge ergometer. Maximal H-reflex, maximal M-wave, Hmax/Mmax-ratio and H-reflex excitability curves were measured during standing rest. Although in young the H-reflex response (Hmax/Mmax) was 6.5% higher during relaxed standing and 19.7% higher during drop jumps (H jump/M jump) than in the elderly group, these differences were not statistically significant. In drop jumps, the elderly subjects had lower jumping height (30.4%, p push-off force (18.0%, p push-off time (31.0% p push-off force (r = 0.833, p push-off time (r = -0.857, p < 0.01) in young but not in the elderly. Correlations between H-reflex response and jumping parameters in young may indicate different jumping and activation strategies in drop jumps. However, it does not fully explain age related differences in jumping performance, since age related differences in H-reflex activity were non-significant. Copyright © 2012 Elsevier Ltd. All rights reserved.

  4. Ski jumping boots limit effective take-off in ski jumping.

    Science.gov (United States)

    Virmavirta, M; Komi, P V

    2001-12-01

    In this study, we measured the vertical and horizontal take-off forces, plantar pressures and activation patterns of four muscles (vastus lateralis, gluteus maximus, tibialis anterior, gastrocnemius) in 10 ski jumpers in simulated laboratory conditions when wearing either training shoes or ski jumping boots. We found significant differences in vertical (P boots condition resulted in a smaller displacement in the final position of the following joint angles: ankle angle (P knee angle (P boots condition, significantly more pressure was recorded under the heel (P knee and hip extensors when wearing jumping boots. We conclude that the stiffness of the structure of the jumping boots may result in a forward shift of pressure, thus limiting the effective vertical force. To avoid this pressure shift, the pattern of movement of simulated take-offs should be carefully controlled, particularly when wearing training shoes.

  5. Between Attraction and Narration: Early Film Adaptations of Fairy Tales

    Directory of Open Access Journals (Sweden)

    Peter Verstraten

    2010-12-01

    Full Text Available Adaptations of fairy tales were particularly popular in the years of early cinema. In the period preceding the year 1903 films consisted of a series of animated tableaux since filmmakers had difficulties in telling a coherent story. Allusions to a well‐known tale could then function as a guide for the spectator. At the same time, filmmakers were fond of experimenting with cinematic tricks, such as stop‐motion techniques and superimpositions. The fairy tale offers a legitimate backdrop for these tricks and these film adaptations even display an excess of the marvelous at the cost of the actual story itself.

  6. Chemical Methods to Knock Down the Amyloid Proteins

    Directory of Open Access Journals (Sweden)

    Na Gao

    2017-06-01

    Full Text Available Amyloid proteins are closely related with amyloid diseases and do tremendous harm to human health. However, there is still a lack of effective strategies to treat these amyloid diseases, so it is important to develop novel methods. Accelerating the clearance of amyloid proteins is a favorable method for amyloid disease treatment. Recently, chemical methods for protein reduction have been developed and have attracted much attention. In this review, we focus on the latest progress of chemical methods that knock down amyloid proteins, including the proteolysis-targeting chimera (PROTAC strategy, the “recognition-cleavage” strategy, the chaperone-mediated autophagy (CMA strategy, the selectively light-activatable organic and inorganic molecules strategy and other chemical strategies.

  7. Bex1 knock out mice show altered skeletal muscle regeneration

    International Nuclear Information System (INIS)

    Koo, Jae Hyung; Smiley, Mark A.; Lovering, Richard M.; Margolis, Frank L.

    2007-01-01

    Bex1 and Calmodulin (CaM) are upregulated during skeletal muscle regeneration. We confirm this finding and demonstrate the novel finding that they interact in a calcium-dependent manner. To study the role of Bex1 and its interaction with CaM in skeletal muscle regeneration, we generated Bex1 knock out (Bex1-KO) mice. These mice appeared to develop normally and are fertile, but displayed a functional deficit in exercise performance compared to wild type (WT) mice. After intramuscular injection of cardiotoxin, which causes extensive and reproducible myotrauma followed by recovery, regenerating muscles of Bex1-KO mice exhibited elevated and prolonged cell proliferation, as well as delayed cell differentiation, compared to WT mice. Thus, our results provide the first evidence that Bex1-KO mice show altered muscle regeneration, and allow us to propose that the interaction of Bex1 with Ca 2+ /CaM may be involved in skeletal muscle regeneration

  8. Jump Tails, Extreme Dependencies, and the Distribution of Stock Returns

    DEFF Research Database (Denmark)

    Bollerslev, Tim; Todorov, Viktor

    We provide a new framework for estimating the systematic and idiosyncratic jump tail risks in financial asset prices. The theory underlying our estimates are based on in-fill asymptotic arguments for directly identifying the systematic and idiosyncratic jumps, together with conventional long...... market portfolio, we find that the distributions of the systematic and idiosyncratic jumps are both generally heavy-tailed and not necessarily symmetric. Our estimates also point to the existence of strong dependencies between the market-wide jumps and the corresponding systematic jump tails for all...... of the stocks in the sample. We also show how the jump tail dependencies deduced from the high-frequency data together with the day-to-day temporal variation in the volatility are able to explain the “extreme” dependencies vis-a-vis the market portfolio....

  9. Fuel effects on knock, heat releases and CARS temperatures in a spark ignition engine

    NARCIS (Netherlands)

    Kalghatgi, G.T.; Golombok, M.; Snowdon, P.

    1995-01-01

    Net heat release, knock characteristics and temperature were derived from in-cylinder pressure and end-gas CARS measurements for different fuels in a single-cylinder engine. The maximum net heat release rate resulting from the final phase of autoignition is closely associated with knock intensity.

  10. Computer simulation of the spatial distribution of optical radiation arising from knocked-out excited particles

    International Nuclear Information System (INIS)

    Gokov, S.P.; Gritsyna, V.V.; Koval', A.G.; Kovtunenko, Yu.I.; Shevchenko, D.I.

    2004-01-01

    The new approach for the explanation of the spatial distribution of the optical radiation arising from knocked-out excited particles is given. Calculated and experimental data for Al (λ=396.1 nm) and Mg (λ=383.8 nm) knocked-out by Ar + (20 keV) beam from MgAl 2 O 4 surface are compared [ru

  11. Computational singular perturbation analysis of super-knock in SI engines

    KAUST Repository

    Jaasim, Mohammed; Tingas, Alexandros; Herná ndez Pé rez, Francisco E.; Im, Hong G.

    2018-01-01

    the deflagration front consumes the air/fuel mixture and two points located at 3 mm from the end-wall where super-knock and mild knock occur. The CSP analysis of the point at the center of the cylinder reveals weak two-stage ignition-like dynamics with a short

  12. The knock study of methanol fuel based on multi-dimensional simulation analysis

    International Nuclear Information System (INIS)

    Zhen, Xudong; Liu, Daming; Wang, Yang

    2017-01-01

    Methanol is an alternative fuel, and considered to be one of the most favorable fuels for engines. In this study, knocking combustion in a developed ORCEM (optical rapid compression and expansion machine) is studied based on the multi-dimensional simulation analysis. The LES (large-eddy simulation) models coupled with methanol chemical reaction kinetics (contains 21-species and 84-elementary reactions) is adopted to study knocking combustion. The results showed that the end-gas auto-ignition first occurred in the position near the chamber wall because of the higher temperature and pressure. The H_2O_2 species could be a good flame front indicator. OH radicals played the major role, and the HCO radicals almost could be ignored during knocking combustion. The HCO radicals generated little, so its concentration during knocking combustion almost may be ignored. The mean reaction intensity results of CH_2O, OH, H_2O_2, and CO were higher than others during knocking combustion. Finally, this paper put forward some new suggestions on the weakness in the knocking combustion researches of methanol fuel. - Highlights: • Knocking combustion of methanol was studied in a developed ORCEM. • The LES coupled with detailed chemical kinetics was adopted to simulation study. • The end-gas auto-ignition first occurred in the place near the chamber wall. • OH radical was the predominant species during knocking combustion. • The H_2O_2 species could be a good flame front indicator.

  13. Once upon Anion: A Tale of Photodetachment

    Science.gov (United States)

    Lineberger, W. Carl

    2013-04-01

    This contribution is very much a personal history of a journey through the wonderful world of anion chemistry, and a tale of how advances in laser technologies, theoretical methods, and computational capabilities continuously enabled advances in our understanding. It is a story of the excitement and joy that come from the opportunity to add to the fabric of science, and to do so by working as a group of excited explorers with common goals. The participants in this journey include me, my students and postdoctoral associates, my collaborators, and our many generous colleagues. It all happened, in the words of the Beatles, “with a little help from my friends.” Actually, it was so much more than a little help!

  14. Influence of magnetic history on flux jump fields

    International Nuclear Information System (INIS)

    Sosnowski, J.

    1986-01-01

    A formalism describing the fields at which flux jumps occur in hard superconductors has been confirmed by the description of an experimentally observed shift of flux jump fields in the second hysteresis loop of a Nb 3 Al superconducting sample. By fitting the theoretical model to experimental data, values of the proportionality parameter between the stability limit and the flux jump field, the first stability limit, and the first penetration field have been estimated

  15. Dynamics and stability of directional jumps in the desert locust.

    Science.gov (United States)

    Gvirsman, Omer; Kosa, Gabor; Ayali, Amir

    2016-01-01

    Locusts are known for their ability to jump large distances to avoid predation. The jump also serves to launch the adult locust into the air in order to initiate flight. Various aspects of this important behavior have been studied extensively, from muscle physiology and biomechanics, to the energy storage systems involved in powering the jump, and more. Less well understood are the mechanisms participating in control of the jump trajectory. Here we utilise video monitoring and careful analysis of experimental directional jumps by adult desert locusts, together with dynamic computer simulation, in order to understand how the locusts control the direction and elevation of the jump, the residual angular velocities resulting from the jump and the timing of flapping-flight initiation. Our study confirms and expands early findings regarding the instrumental role of the initial body position and orientation. Both real-jump video analysis and simulations based on our expanded dynamical model demonstrate that the initial body coordinates of position (relative to the hind-legs ground-contact points) are dominant in predicting the jumps' azimuth and elevation angles. We also report a strong linear correlation between the jumps' pitch-angular-velocity and flight initiation timing, such that head downwards rotations lead to earlier wing opening. In addition to offering important insights into the bio-mechanical principles of locust jumping and flight initiation, the findings from this study will be used in designing future prototypes of a bio-inspired miniature jumping robot that will be employed in animal behaviour studies and environmental monitoring applications.

  16. Optimized knock-in of point mutations in zebrafish using CRISPR/Cas9.

    Science.gov (United States)

    Prykhozhij, Sergey V; Fuller, Charlotte; Steele, Shelby L; Veinotte, Chansey J; Razaghi, Babak; Robitaille, Johane M; McMaster, Christopher R; Shlien, Adam; Malkin, David; Berman, Jason N

    2018-06-14

    We have optimized point mutation knock-ins into zebrafish genomic sites using clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 reagents and single-stranded oligodeoxynucleotides. The efficiency of knock-ins was assessed by a novel application of allele-specific polymerase chain reaction and confirmed by high-throughput sequencing. Anti-sense asymmetric oligo design was found to be the most successful optimization strategy. However, cut site proximity to the mutation and phosphorothioate oligo modifications also greatly improved knock-in efficiency. A previously unrecognized risk of off-target trans knock-ins was identified that we obviated through the development of a workflow for correct knock-in detection. Together these strategies greatly facilitate the study of human genetic diseases in zebrafish, with additional applicability to enhance CRISPR-based approaches in other animal model systems.

  17. Gene cassette knock-in in mammalian cells and zygotes by enhanced MMEJ.

    Science.gov (United States)

    Aida, Tomomi; Nakade, Shota; Sakuma, Tetsushi; Izu, Yayoi; Oishi, Ayu; Mochida, Keiji; Ishikubo, Harumi; Usami, Takako; Aizawa, Hidenori; Yamamoto, Takashi; Tanaka, Kohichi

    2016-11-28

    Although CRISPR/Cas enables one-step gene cassette knock-in, assembling targeting vectors containing long homology arms is a laborious process for high-throughput knock-in. We recently developed the CRISPR/Cas-based precise integration into the target chromosome (PITCh) system for a gene cassette knock-in without long homology arms mediated by microhomology-mediated end-joining. Here, we identified exonuclease 1 (Exo1) as an enhancer for PITCh in human cells. By combining the Exo1 and PITCh-directed donor vectors, we achieved convenient one-step knock-in of gene cassettes and floxed allele both in human cells and mouse zygotes. Our results provide a technical platform for high-throughput knock-in.

  18. A Photographic Study of Combustion and Knock in a Spark-Ignition Engine

    Science.gov (United States)

    Rothrock, A M; Spencer, R C

    1938-01-01

    Report presents the results of a photographic study of the combustion in a spark-ignition engine using both Schlieren and flame photographs taken at high rates of speed. Although shock waves are present after knock occurs, there was no evidence of any type of sonic or supersonic compression waves existing in the combustion gases prior to the occurrence of knock. Artificially induced shock waves in the engine did not in themselves cause knock. The photographs also indicate that, although auto-ignition ahead of the flame front may occur in conjunction with knock, it is not necessary for the occurrence of knock. There is also evidence that the reaction is not completed in the flame front but continues for some time after the flame front has passed through the charge.

  19. Using Jack Tales in a Second Grade Class.

    Science.gov (United States)

    Brown, Doris

    1987-01-01

    Describes a project in which Kentucky second grades developed puppet shows and photography activities based on traditional Appalachian oral tales. Discusses student progress in language arts skills, creativity, use of audiovisual equipment, and group cooperation. (SV)

  20. SCIENTIFIC TALES AND DEMOCRATIC PROCESSES IN AN AGE ...

    African Journals Online (AJOL)

    user

    others as being philosophers and scientists in one single swoop. The ... methodic forum. .... universe as its object and discovery of the quiddity of phenomena as ... 3. The Politics of Global Warming and the Implications of Tales of Science.

  1. 'The crocodile's wife' – a tale of transformations | Wendland ...

    African Journals Online (AJOL)

    nthano) about a magical personal transformation, as this metaphorical story has been subsequently adapted for a dramatised radio representation. The artistic transformer, Julius Chongo, took a recording of the original village tale and used its ...

  2. Another Tale of Two Cities: Contestation of Globalization in Odia ...

    African Journals Online (AJOL)

    Another Tale of Two Cities: Contestation of Globalization in Odia Ofeimun's ... state, in all its social, economic and cultural aspirations, coupled with its trappings of ... as a result of such issues as capitalism, race, nationality, identity and nativity.

  3. Biomechanics research in ski jumping, 1991-2006.

    Science.gov (United States)

    Schwameder, Hermann

    2008-01-01

    In this paper, I review biomechanics research in ski jumping with a specific focus on publications presented between 1991 and 2006 on performance enhancement, limiting factors of the take-off, specific training and conditioning, aerodynamics, and safety. The first section presents a brief description of ski jumping phases (in-run, take-off, early flight, stable flight, and landing) regarding the biomechanical and functional fundamentals. The most important and frequently used biomechanical methods in ski jumping (kinematics, ground reaction force analyses, muscle activation patterns, aerodynamics) are summarized in the second section. The third section focuses on ski jumping articles and research findings published after the establishment of the V-technique in 1991, as the introduction of this technique has had a major influence on performance enhancement, ski jumping regulations, and the construction of hill profiles. The final section proposes topics for future research in the biomechanics of ski jumping, including: take-off and early flight and the relative roles of vertical velocity and forward somersaulting angular momentum; optimal jumping patterns utilizing the capabilities of individual athletes; development of kinematic and kinetic feedback systems for hill jumps; comparisons of simulated and hill jumps; effect of equipment modifications on performance and safety enhancement.

  4. Jump phenomena. [large amplitude responses of nonlinear systems

    Science.gov (United States)

    Reiss, E. L.

    1980-01-01

    The paper considers jump phenomena composed of large amplitude responses of nonlinear systems caused by small amplitude disturbances. Physical problems where large jumps in the solution amplitude are important features of the response are described, including snap buckling of elastic shells, chemical reactions leading to combustion and explosion, and long-term climatic changes of the earth's atmosphere. A new method of rational functions was then developed which consists of representing the solutions of the jump problems as rational functions of the small disturbance parameter; this method can solve jump problems explicitly.

  5. Effect of drop jump technique on the reactive strength index.

    Science.gov (United States)

    Struzik, Artur; Juras, Grzegorz; Pietraszewski, Bogdan; Rokita, Andrzej

    2016-09-01

    The basic drill of plyometric training aimed at improving lower limb power and jump height is a drop jump. This exercise can be performed using different techniques, which substantially affects jump variables. Therefore, the aim of this study was to compare the values of the reactive strength index (RSI) for countermovement drop jumps (CDJs) and bounce drop jumps (BDJs). The study was carried out in a group of 8 male youth basketball players. The tests were conducted using the AMTI BP600900 force plate to measure ground reaction forces and the Noraxon MyoMotion system to record kinematic data. Each player performed two CDJs and two BDJs from the height of 15, 30, 45 and 60 cm. The RSI was calculated as a ratio of jump height and contact time. Moreover, the RSI was determined for the amortization and take-off phases separately. Significant differences (p jumps from 30, 45 and 60 cm. Differences in RSI values for jumps from 15 cm were not significant. Furthermore, CDJ height values were significantly higher (p jump technique that is commonly performed by basketball players.

  6. Impact of wave phase jumps on stochastic heating

    International Nuclear Information System (INIS)

    Zasenko, V.I.; Zagorodny, A.G.; Cherniak, O.M.

    2016-01-01

    Interaction of charged particles with fields of random waves brings about known effects of stochastic acceleration and heating. Jumps of wave phases can increase the intensity of these processes substantially. Numerical simulation of particle heating and acceleration by waves with regular phases, waves with jumping phase and stochastic electric field impulses is performed. Comparison of the results shows that to some extent an impact of phase jumps is similar to the action of separate field impulses. Jumps of phase not only increase the intensity of resonant particle heating but involves in this process non-resonant particles from a wide range of initial velocities

  7. Jump Testing and the Speed of Market Adjustment

    DEFF Research Database (Denmark)

    Rasmussen, Torben B.

    Asymptotic properties of jump tests rely on the property that any jump occurs within a single time interval no matter what the observation frequency is. Market microstructure effects in relation to news-induced revaluation of the underlying variable is likely to make this an unrealistic assumption...... for high-frequency transaction data. To capture these microstructure effects, this paper suggests a model in which market prices adjust gradually to jumps in the underlying effcient price. A case study illustrates the empirical relevance of the model, and the performance of different jump tests...

  8. Development of a Minimally Actuated Jumping-Rolling Robot

    Directory of Open Access Journals (Sweden)

    Thanhtam Ho

    2015-04-01

    Full Text Available This paper presents development of a hybrid mobile robot in order to take advantage of both rolling and jumping locomotion on the ground. According to the unique design of the mechanism, the robot is able to execute both jumping and rolling skilfully by using only one DC motor. Changing the centre of gravity enables rolling of the robot and storage of energy is utilized for jumping. Mechanism design and control logic are validated by computer simulation. Simulation results show that the robot can jump nearly 1.3 times its diameter and roll at the speed of 3.3 times its diameter per second.

  9. Effect of drop jump technique on the reactive strength index

    Directory of Open Access Journals (Sweden)

    Struzik Artur

    2016-09-01

    Full Text Available The basic drill of plyometric training aimed at improving lower limb power and jump height is a drop jump. This exercise can be performed using different techniques, which substantially affects jump variables. Therefore, the aim of this study was to compare the values of the reactive strength index (RSI for countermovement drop jumps (CDJs and bounce drop jumps (BDJs. The study was carried out in a group of 8 male youth basketball players. The tests were conducted using the AMTI BP600900 force plate to measure ground reaction forces and the Noraxon MyoMotion system to record kinematic data. Each player performed two CDJs and two BDJs from the height of 15, 30, 45 and 60 cm. The RSI was calculated as a ratio of jump height and contact time. Moreover, the RSI was determined for the amortization and take-off phases separately. Significant differences (p < 0.05 between RSI values for CDJs and BDJs were recorded for jumps from 30, 45 and 60 cm. Differences in RSI values for jumps from 15 cm were not significant. Furthermore, CDJ height values were significantly higher (p < 0.05 than the values recorded for BDJs. Times of contact, amortization and take-off during BDJs were significantly shorter (p < 0.05 than the respective values obtained for CDJs. Therefore, the use of the RSI to monitor plyometric training should be based on the drop jump technique that is commonly performed by basketball players.

  10. Measurement of K-shell absorption jump factors and jump ratios in some lanthanide elements using EDXRF technique

    International Nuclear Information System (INIS)

    Polat, Recep; İçelli, Orhan; Yalçın, Zeynel; Pesen, Erhan; Orak, Salim

    2013-01-01

    Highlights: ► Mass attenuation coefficients, jump factor and jump ratio for lanthanide elements are obtained. ► The method used in this experiment is combined both transmission and scattering geometry. ► Secondary gamma rays energy is 59.5 keV. ► Experimental values of jump factor and jump ratio for K shell are new. ► The experimental values are in good agreement with those calculated theoretically. - Abstract: 59.5 keV gamma rays scattered by an aluminum foil have been used as a radiation source to measure the absorption jump factor and jump ratios for absorbers Ce, Pr, Nd, Sm, Eu and Tb. The theoretical and experimental values are compared with the corresponding ones in the literature

  11. Locally Perturbed Random Walks with Unbounded Jumps

    OpenAIRE

    Paulin, Daniel; Szász, Domokos

    2010-01-01

    In \\cite{SzT}, D. Sz\\'asz and A. Telcs have shown that for the diffusively scaled, simple symmetric random walk, weak convergence to the Brownian motion holds even in the case of local impurities if $d \\ge 2$. The extension of their result to finite range random walks is straightforward. Here, however, we are interested in the situation when the random walk has unbounded range. Concretely we generalize the statement of \\cite{SzT} to unbounded random walks whose jump distribution belongs to th...

  12. Multiobjective Optimization Methodology A Jumping Gene Approach

    CERN Document Server

    Tang, KS

    2012-01-01

    Complex design problems are often governed by a number of performance merits. These markers gauge how good the design is going to be, but can conflict with the performance requirements that must be met. The challenge is reconciling these two requirements. This book introduces a newly developed jumping gene algorithm, designed to address the multi-functional objectives problem and supplies a viably adequate solution in speed. The text presents various multi-objective optimization techniques and provides the technical know-how for obtaining trade-off solutions between solution spread and converg

  13. Intertextuality in the Tales of Rabbi Nahman of Bratslav

    DEFF Research Database (Denmark)

    Schleicher, Marianne

    not yet been undertaken. As the first comprehensive scholarly work on the whole selection of tales and contrary to previous scholarship, this book does not reduce the tales to biographical expressions of Nahman's tormented soul and messianic aspirations. Instead, it treats them as religious literature...... where the concept of "intertextuality" is considered essential to explain how Nahman defines his theology of redemption and invites his listeners and readers to appropriate his religious world-view....

  14. Determinant Factors of the Squat Jump in Sprinting and Jumping Athletes

    Directory of Open Access Journals (Sweden)

    González-Badillo Juan José

    2017-08-01

    Full Text Available The aim of this study was to assess the relationship between strength variables and maximum velocity (Vmax in the squat jump (SJ in sprinting and jumping athletes. Thirty-two sprinting and jumping athletes of national level (25.4 ± 4.5 years; 79.4 ± 6.9 kg and 180.4 ± 6.0 cm participated in the study. Vmax in the SJ showed significant relationships with peak force 1 (PF1 (r = 0.82, p ≤ 0.001, peak force 2 (PF2 (r = 0.68, p ≤ 0.001, PF2 by controlling for PF1 (r = 0.30, non-significant, the maximum rate of force development at peak force 1 (RFDmax1 (r = 0.62, p ≤ 0.001, mean RFD 1 (RFDmean1 (r = 0.48, p ≤ 0.01, mean RFD 2 (RFDmean2 (r = 0.70, p ≤ 0.001, force at RFDmax1 (r = 0.36, p ≤ 0.05, force at RFDmax2 (r = 0.83, p ≤ 0.001 and force at RFDmax2 by controlling for PF1 (r = 0.40, p ≤ 0.05. However, Vmax in the SJ was associated negatively with the ratio PF2/PF1 (r = -0.54, p ≤ 0.01, time at peak force 2 (Tp2 (r = -0.64, p ≤ 0.001 and maximum rate of force development at peak force 2 (RFDmax2 (r = -0.71, p ≤ 0.001. These findings indicate that the peak force achieved at the beginning of the movement (PF1 is the main predictor of performance in jumping, although the RFDmax values and the ratio PF2/PF1 are also variables to be taken into account when analyzing the determinant factors of vertical jumping.

  15. Variability of Plyometric and Ballistic Exercise Technique Maintains Jump Performance.

    Science.gov (United States)

    Chandler, Phillip T; Greig, Matthew; Comfort, Paul; McMahon, John J

    2018-06-01

    Chandler, PT, Greig, M, Comfort, P, and McMahon, JJ. Variability of plyometric and ballistic exercise technique maintains jump performance. J Strength Cond Res 32(6): 1571-1582, 2018-The aim of this study was to investigate changes in vertical jump technique over the course of a training session. Twelve plyometric and ballistic exercise-trained male athletes (age = 23.4 ± 4.6 years, body mass = 78.7 ± 18.8 kg, height = 177.1 ± 9.0 cm) performed 3 sets of 10 repetitions of drop jump (DJ), rebound jump (RJ) and squat jump (SJ). Each exercise was analyzed from touchdown to peak joint flexion and peak joint flexion to take-off. Squat jump was analyzed from peak joint flexion to take-off only. Jump height, flexion and extension time and range of motion, and instantaneous angles of the ankle, knee, and hip joints were measured. Separate 1-way repeated analyses of variance compared vertical jump technique across exercise sets and repetitions. Exercise set analysis found that SJ had lower results than DJ and RJ for the angle at peak joint flexion for the hip, knee, and ankle joints and take-off angle of the hip joint. Exercise repetition analysis found that the ankle joint had variable differences for the angle at take-off, flexion, and extension time for RJ. The knee joint had variable differences for flexion time for DJ and angle at take-off and touchdown for RJ. There was no difference in jump height. Variation in measured parameters across repetitions highlights variable technique across plyometric and ballistic exercises. This did not affect jump performance, but likely maintained jump performance by overcoming constraints (e.g., level of rate coding).

  16. CAPTURE OF TROJANS BY JUMPING JUPITER

    International Nuclear Information System (INIS)

    Nesvorný, David; Vokrouhlický, David; Morbidelli, Alessandro

    2013-01-01

    Jupiter Trojans are thought to be survivors of a much larger population of planetesimals that existed in the planetary region when planets formed. They can provide important constraints on the mass and properties of the planetesimal disk, and its dispersal during planet migration. Here, we tested a possibility that the Trojans were captured during the early dynamical instability among the outer planets (aka the Nice model), when the semimajor axis of Jupiter was changing as a result of scattering encounters with an ice giant. The capture occurs in this model when Jupiter's orbit and its Lagrange points become radially displaced in a scattering event and fall into a region populated by planetesimals (that previously evolved from their natal transplanetary disk to ∼5 AU during the instability). Our numerical simulations of the new capture model, hereafter jump capture, satisfactorily reproduce the orbital distribution of the Trojans and their total mass. The jump capture is potentially capable of explaining the observed asymmetry in the number of leading and trailing Trojans. We find that the capture probability is (6-8) × 10 –7 for each particle in the original transplanetary disk, implying that the disk contained (3-4) × 10 7 planetesimals with absolute magnitude H disk ∼ 14-28 M Earth , is consistent with the mass deduced from recent dynamical simulations of the planetary instability.

  17. A predictive model for knock onset in spark-ignition engines with cooled EGR

    International Nuclear Information System (INIS)

    Chen, Longhua; Li, Tie; Yin, Tao; Zheng, Bin

    2014-01-01

    Highlights: • Ratio of specific heats should be used as variable in development of knock model. • Increases in EGR or excess air ratio lead to increases in the ratio of specific heats. • The widely-used Douaud–Eyzat correlation fails to predict the knock onset when increasing EGR. • The newly developed model including p, T, EGR and λ as variables predicts the knock onset accurately. • Effect of temperature at intake valve closure on the predicted knock onset is relatively small. - Abstract: A predictive knock model is crucial for one dimensional (1-D) engine cycle simulation that has been proven to be a powerful tool in both optimization of the conceptual design and reduction of calibration efforts in development of spark-ignition (SI) engines. With application of advanced technologies such as exhaust gas recirculation (EGR) in modern SI engines, update of knock model is needed to give an acceptable prediction of knock onset. In this study, bench tests of a turbocharged gasoline SI engine with cooled EGR system operated under knocking conditions were conducted, the cylinder pressure traces were analyzed by the band-pass filtering technique, and the crank angle of knock onset was determined by the signal energy ratio (SER) and image processing method. A knock model considering multi-variable effects including pressure, temperature, EGR ratio and excess air ratio (λ) is formulated and calibrated with the experimental data using the multi-island genetic algorithm (GA). The calculation method of the end gas temperature, the impacts of the ratio of specific heats as well as the temperature at the intake valve closure on the end gas temperature are discussed. The performance of the new model is compared with the widely-used phenomenological knock models such as Douaud–Eyzat model and Hoepke model. While the widely-used knock models fail to give acceptable predictions when increasing EGR with fuel enrichment operations, the new model predicts the knock

  18. Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors.

    Science.gov (United States)

    Thakore, Pratiksha I; Gersbach, Charles A

    2016-01-01

    Transcription activator-like effectors (TALEs) are modular DNA-binding proteins that can be fused to a variety of effector domains to regulate the epigenome. Nucleotide recognition by TALE monomers follows a simple cipher, making this a powerful and versatile method to activate or repress gene expression. Described here are methods to design, assemble, and test TALE transcription factors (TALE-TFs) for control of endogenous gene expression. In this protocol, TALE arrays are constructed by Golden Gate cloning and tested for activity by transfection and quantitative RT-PCR. These methods for engineering TALE-TFs are useful for studies in reverse genetics and genomics, synthetic biology, and gene therapy.

  19. Knock probability estimation through an in-cylinder temperature model with exogenous noise

    Science.gov (United States)

    Bares, P.; Selmanaj, D.; Guardiola, C.; Onder, C.

    2018-01-01

    This paper presents a new knock model which combines a deterministic knock model based on the in-cylinder temperature and an exogenous noise disturbing this temperature. The autoignition of the end-gas is modelled by an Arrhenius-like function and the knock probability is estimated by propagating a virtual error probability distribution. Results show that the random nature of knock can be explained by uncertainties at the in-cylinder temperature estimation. The model only has one parameter for calibration and thus can be easily adapted online. In order to reduce the measurement uncertainties associated with the air mass flow sensor, the trapped mass is derived from the in-cylinder pressure resonance, which improves the knock probability estimation and reduces the number of sensors needed for the model. A four stroke SI engine was used for model validation. By varying the intake temperature, the engine speed, the injected fuel mass, and the spark advance, specific tests were conducted, which furnished data with various knock intensities and probabilities. The new model is able to predict the knock probability within a sufficient range at various operating conditions. The trapped mass obtained by the acoustical model was compared in steady conditions by using a fuel balance and a lambda sensor and differences below 1 % were found.

  20. The world price of jump and volatility risk

    NARCIS (Netherlands)

    Driessen, J.; Maenhout, P.

    2006-01-01

    Jump and volatility risk are important for understanding equity returns, option pricing and asset allocation. This paper is the first to study international integration of markets for jump and volatility risk, using data on index options for each of the three main global markets: US S&P 500 index

  1. Asymptotic inference for jump diffusions with state-dependent intensity

    NARCIS (Netherlands)

    Becheri, Gaia; Drost, Feico; Werker, Bas

    2016-01-01

    We establish the local asymptotic normality property for a class of ergodic parametric jump-diffusion processes with state-dependent intensity and known volatility function sampled at high frequency. We prove that the inference problem about the drift and jump parameters is adaptive with respect to

  2. Long multiplication by instruction sequences with backward jump instructions

    NARCIS (Netherlands)

    Bergstra, J.A.; Middelburg, C.A.

    2013-01-01

    For each function on bit strings, its restriction to bit strings of any given length can be computed by a finite instruction sequence that contains only instructions to set and get the content of Boolean registers, forward jump instructions, and a termination instruction. Backward jump instructions

  3. Knee Muscular Control During Jump Landing in Multidirections.

    Science.gov (United States)

    Sinsurin, Komsak; Vachalathiti, Roongtiwa; Jalayondeja, Wattana; Limroongreungrat, Weerawat

    2016-06-01

    Jump landing is a complex movement in sports. While competing and practicing, athletes frequently perform multi-planar jump landing. Anticipatory muscle activity could influence the amount of knee flexion and prepare the knee for dynamic weight bearing such as landing tasks. The aim of the present study was to examine knee muscle function and knee flexion excursion as athletes naturally performed multi-direction jump landing. Eighteen male athletes performed the jump-landing test in four directions: forward (0°), 30° diagonal, 60° diagonal, and lateral (90°). Muscles tested were vastus medialis (VM), vastus lateralis (VL), rectus femoris (RF), semitendinosus (ST), and biceps femoris (BF). A Vicon(TM) 612 workstation collected the kinematic data. An electromyography was synchronized with the Vicon(TM) Motion system to quantify dynamic muscle function. Repeated measure ANOVA was used to analyze the data. Jump-landing direction significantly influenced (P jump landing. A higher risk of knee injury might occur during lateral jump landing than forward and diagonal directions. Athletes should have more practice in jump landing in lateral direction to avoid injury. Landing technique with high knee flexion in multi-directions should be taught to jumpers for knee injury prevention.

  4. Immediate Effects of Different Trunk Exercise Programs on Jump Performance.

    Science.gov (United States)

    Imai, A; Kaneoka, K; Okubo, Y; Shiraki, H

    2016-03-01

    The aim of this study was to investigate the immediate effects of trunk stabilization exercise (SE) and conventional trunk exercise (CE) programs on jump performance. 13 adolescent male soccer players performed 2 kinds of jump testing before and immediate after 3 experimental conditions: SE, CE, and non-exercise (NE). The SE program consisted of the elbow-toe, hand-knee, and back bridge, and the CE program consisted of the sit-up, sit-up with trunk rotation and back extension. Testing of a countermovement jump (CMJ) and rebound jump (RJ) were performed to assess jump performance. Jump height of the CMJ and RJ-index, contact time, and jump height of the RJ were analyzed. The RJ index was improved significantly only after SE (p=0.017). However, contact time and jump height did not improve significantly in the SE condition. Moreover, no significant interaction or main effects of time or group were observed in the CMJ. Consequently, this study showed the different immediate effect on the RJ between the SE and CE, and suggested the possibility that the SE used in this study is useful as a warm-up program to improve the explosive movements. © Georg Thieme Verlag KG Stuttgart · New York.

  5. A Jump-Diffusion Model with Stochastic Volatility and Durations

    DEFF Research Database (Denmark)

    Wei, Wei; Pelletier, Denis

    jumps in two ways: as exogenous sampling intervals, and through the interaction with volatility. We adopt a bivariate Ornstein-Ulenbeck process to model intraday volatility and conditional duration. We develop a MCMC algorithm for the inference on irregularly spaced multivariate processes with jumps...

  6. Dynamics of force and muscle stimulation in human vertical jumping

    NARCIS (Netherlands)

    Bobbert, M.F.; van Zandwijk, J.P.

    1999-01-01

    PURPOSE: The purpose of this study was to gain insight into the importance of stimulation dynamics for force development in human vertical jumping. METHODS: Maximum height squat jumps were performed by 21 male subjects. As a measure of signal dynamics, rise time (RT) was used, i.e., the time taken

  7. Role of the hamstrings in human vertical jumping

    NARCIS (Netherlands)

    Bobbert, Maarten F.

    1996-01-01

    In some human subjects performing maximum-height squat jumps, the EMG-pattern of semitendinosus is bi-phasic and that of biceps femoris is mono-phasic. The purpose of this study was to investigate the roles of biceps femoris and semitendinosus in squat jumping, and to explain why they are different.

  8. Forces exerted by jumping children: A pilot study

    NARCIS (Netherlands)

    Moes, C.C.M.; Bakker, H.E.

    1998-01-01

    This article reports on a pilot study of the loads exerted vertically by children when jumping. The subjects of the study were 17 children, aged from two to twelve years. Measurements were made using video recordings and a force-plate. The influence of the stiffness of the base and of jumping with

  9. On Pathos Adjacency Cut Vertex Jump Graph of a Tree

    OpenAIRE

    Nagesh.H.M; R.Chandrasekhar

    2014-01-01

    In this paper the concept of pathos adjacency cut vertex jump graph PJC(T) of a tree T is introduced. We also present a characterization of graphs whose pathos adjacency cut vertex jump graphs are planar, outerplanar, minimally non-outerplanar, Eulerian and Hamiltonian.

  10. Teaching Jump Rope to Children with Visual Impairments

    Science.gov (United States)

    Lieberman, Lauren J.; Schedlin, Haley; Pierce, Tristan

    2009-01-01

    This article presents strategies for jumping rope for children with visual impairments. Giving choices related to the types of rope and the use of mats is important. In addition, using appropriate instructional strategies and modifications will make jumping rope a skill that the children will enjoy and will lead to their involvement in other…

  11. The validity and reliability of the my jump 2 app for measuring the reactive strength index and drop jump performance.

    Science.gov (United States)

    Haynes, Tom; Bishop, Chris; Antrobus, Mark; Brazier, Jon

    2018-03-27

    This is the first study to independently assess the concurrent validity and reliability of the My Jump 2 app for measuring drop jump performance. It is also the first to evaluate the app's ability to measure the reactive strength index (RSI). Fourteen male sport science students (age: 29.5 ± 9.9 years) performed three drop jumps from 20 cm and 40 cm (totalling 84 jumps), assessed via a force platform and the My Jump 2 app. Reported metrics included reactive strength index, jump height, ground contact time, and mean power. Measurements from both devices were compared using the intraclass correlation coefficient (ICC), Pearson product moment correlation coefficient (r), Cronbach's alpha (α), coefficient of variation (CV) and BlandAltman plots. Near perfect agreement was seen between devices at 20 cm for RSI (ICC = 0.95) and contact time (ICC = 0.99) and at 40 cm for RSI (ICC = 0.98), jump height (ICC = 0.96) and contact time (ICC = 0.92); with very strong agreement seen at 20 cm for jump height (ICC = 0.80). In comparison with the force plate the app showed good validity for RSI (20 cm: r = 0.94; 40 cm; r = 0.97), jump height (20 cm: r = 0.80; 40 cm; r = 0.96) and contact time (20 cm = 0.96; 40 cm; r = 0.98). The results of the present study show that the My Jump 2 app is a valid and reliable tool for assessing drop jump performance.

  12. Control strategy of maximum vertical jumps: The preferred countermovement depth may not be fully optimized for jump height

    Directory of Open Access Journals (Sweden)

    Mandic Radivoj

    2016-09-01

    Full Text Available The aim of the present study was to explore the control strategy of maximum countermovement jumps regarding the preferred countermovement depth preceding the concentric jump phase. Elite basketball players and physically active non-athletes were tested on the jumps performed with and without an arm swing, while the countermovement depth was varied within the interval of almost 30 cm around its preferred value. The results consistently revealed 5.1-11.2 cm smaller countermovement depth than the optimum one, but the same difference was more prominent in non-athletes. In addition, although the same differences revealed a marked effect on the recorded force and power output, they reduced jump height for only 0.1-1.2 cm. Therefore, the studied control strategy may not be based solely on the countermovement depth that maximizes jump height. In addition, the comparison of the two groups does not support the concept of a dual-task strategy based on the trade-off between maximizing jump height and minimizing the jumping quickness that should be more prominent in the athletes that routinely need to jump quickly. Further research could explore whether the observed phenomenon is based on other optimization principles, such as the minimization of effort and energy expenditure. Nevertheless, future routine testing procedures should take into account that the control strategy of maximum countermovement jumps is not fully based on maximizing the jump height, while the countermovement depth markedly confound the relationship between the jump height and the assessed force and power output of leg muscles.

  13. Control strategy of maximum vertical jumps: The preferred countermovement depth may not be fully optimized for jump height.

    Science.gov (United States)

    Mandic, Radivoj; Knezevic, Olivera M; Mirkov, Dragan M; Jaric, Slobodan

    2016-09-01

    The aim of the present study was to explore the control strategy of maximum countermovement jumps regarding the preferred countermovement depth preceding the concentric jump phase. Elite basketball players and physically active non-athletes were tested on the jumps performed with and without an arm swing, while the countermovement depth was varied within the interval of almost 30 cm around its preferred value. The results consistently revealed 5.1-11.2 cm smaller countermovement depth than the optimum one, but the same difference was more prominent in non-athletes. In addition, although the same differences revealed a marked effect on the recorded force and power output, they reduced jump height for only 0.1-1.2 cm. Therefore, the studied control strategy may not be based solely on the countermovement depth that maximizes jump height. In addition, the comparison of the two groups does not support the concept of a dual-task strategy based on the trade-off between maximizing jump height and minimizing the jumping quickness that should be more prominent in the athletes that routinely need to jump quickly. Further research could explore whether the observed phenomenon is based on other optimization principles, such as the minimization of effort and energy expenditure. Nevertheless, future routine testing procedures should take into account that the control strategy of maximum countermovement jumps is not fully based on maximizing the jump height, while the countermovement depth markedly confound the relationship between the jump height and the assessed force and power output of leg muscles.

  14. Engineering customized TALE nucleases (TALENs) and TALE transcription factors by fast ligation-based automatable solid-phase high-throughput (FLASH) assembly.

    Science.gov (United States)

    Reyon, Deepak; Maeder, Morgan L; Khayter, Cyd; Tsai, Shengdar Q; Foley, Jonathan E; Sander, Jeffry D; Joung, J Keith

    2013-07-01

    Customized DNA-binding domains made using transcription activator-like effector (TALE) repeats are rapidly growing in importance as widely applicable research tools. TALE nucleases (TALENs), composed of an engineered array of TALE repeats fused to the FokI nuclease domain, have been used successfully for directed genome editing in various organisms and cell types. TALE transcription factors (TALE-TFs), consisting of engineered TALE repeat arrays linked to a transcriptional regulatory domain, have been used to up- or downregulate expression of endogenous genes in human cells and plants. This unit describes a detailed protocol for the recently described fast ligation-based automatable solid-phase high-throughput (FLASH) assembly method. FLASH enables automated high-throughput construction of engineered TALE repeats using an automated liquid handling robot or manually using a multichannel pipet. Using the automated approach, a single researcher can construct up to 96 DNA fragments encoding TALE repeat arrays of various lengths in a single day, and then clone these to construct sequence-verified TALEN or TALE-TF expression plasmids in a week or less. Plasmids required for FLASH are available by request from the Joung lab (http://eGenome.org). This unit also describes improvements to the Zinc Finger and TALE Targeter (ZiFiT Targeter) web server (http://ZiFiT.partners.org) that facilitate the design and construction of FLASH TALE repeat arrays in high throughput. © 2013 by John Wiley & Sons, Inc.

  15. Option Valuation with Observable Volatility and Jump Dynamics

    DEFF Research Database (Denmark)

    Christoffersen, Peter; Feunou, Bruno; Jeon, Yoontae

    Under very general conditions, the total quadratic variation of a jump-diffusion process can be decomposed into diffusive volatility and squared jump variation. We use this result to develop a new option valuation model in which the underlying asset price exhibits volatility and jump intensity...... dynamics. The volatility and jump intensity dynamics in the model are directly driven by model-free empirical measures of diffusive volatility and jump variation. Because the empirical measures are observed in discrete intervals, our option valuation model is cast in discrete time, allowing...... for straightforward filtering and estimation of the model. Our model belongs to the affine class enabling us to derive the conditional characteristic function so that option values can be computed rapidly without simulation. When estimated on S&P500 index options and returns the new model performs well compared...

  16. Nonstandard jump functions for radically symmetric shock waves

    International Nuclear Information System (INIS)

    Baty, Roy S.; Tucker, Don H.; Stanescu, Dan

    2008-01-01

    Nonstandard analysis is applied to derive generalized jump functions for radially symmetric, one-dimensional, magnetogasdynamic shock waves. It is assumed that the shock wave jumps occur on infinitesimal intervals and the jump functions for the physical parameters occur smoothly across these intervals. Locally integrable predistributions of the Heaviside function are used to model the flow variables across a shock wave. The equations of motion expressed in nonconservative form are then applied to derive unambiguous relationships between the jump functions for the physical parameters for two families of self-similar flows. It is shown that the microstructures for these families of radially symmetric, magnetogasdynamic shock waves coincide in a nonstandard sense for a specified density jump function.

  17. Study of brittle crack jump rate using acoustic emission method

    International Nuclear Information System (INIS)

    Yasnij, P.V.; Pokrovskij, V.V.; Strizhalo, V.A.; Dobrovol'skij, Yu.V.

    1987-01-01

    A new peocedure is elaborated to detect brittle jumps of small length (0.1...5mm) occuring both inside the specimen and along the crack front under static and cyclic loading using the phenomena of acoustic emission (AE). Recording of the crack start and stop moments with an AE sensor as well as evaluation of the brittle crack jump length by the after-failure specimen fracture make it possible to find the mean crack propagation rate. Experimental dependences are obtained for the crack propagation rate with a brittle crack jump in steel 15Kh2MFA (σ B =1157 MPa, σ 0.2 =100 MPa) at 293 K and under cyclic loading as a function of the jump length and also as a function of the critical stress intensity factor K jc i corresponding to the crack jump

  18. Approaching stationarity: competition between long jumps and long waiting times

    International Nuclear Information System (INIS)

    Dybiec, Bartłomiej

    2010-01-01

    Within the continuous-time random walk (CTRW) scenarios, properties of the overall motion are determined by the waiting time and the jump length distributions. In the decoupled case, with power-law distributed waiting times and jump lengths, the CTRW scenario is asymptotically described by the double (space and time) fractional Fokker–Planck equation. Properties of a system described by such an equation are determined by the subdiffusion parameter and the jump length exponent. Nevertheless, the stationary state is determined solely by the jump length distribution and the potential. The waiting time distribution determines only the rate of convergence to the stationary state. Here, we inspect the competition between long waiting times and long jumps and how this competition is reflected in the way in which a stationary state is reached. In particular, we show that the distance between a time-dependent and a stationary solution changes in time as a double power law

  19. The hydraulic jump and ripples in liquid helium

    International Nuclear Information System (INIS)

    Rolley, E.; Guthmann, C.; Pettersen, M.S.

    2007-01-01

    We have studied the characteristics of the circular hydraulic jump using liquid helium. Surprisingly, the radius of the jump does not change at the superfluid transition. We think that the flow is still dissipative below the lambda point because the velocity exceeds the critical one. The jump radius R j is compared with various models. In our parameter range, we find that the jump can be treated as a shock, and that capillary effects are important. Below the superfluid transition, we observed a standing capillary wave between the impact of the jet and the jump. Assuming that the superfluid flow can be described with an effective viscosity, we calculate the wave vector and thus obtain the value of the liquid thickness, which is in reasonable agreement with predictions. However, the spatial variation of the wave amplitude depends much more strongly on temperature than we calculate

  20. Ballistic Jumping Drops on Superhydrophobic Surfaces via Electrostatic Manipulation.

    Science.gov (United States)

    Li, Ning; Wu, Lei; Yu, Cunlong; Dai, Haoyu; Wang, Ting; Dong, Zhichao; Jiang, Lei

    2018-02-01

    The ballistic ejection of liquid drops by electrostatic manipulating has both fundamental and practical implications, from raindrops in thunderclouds to self-cleaning, anti-icing, condensation, and heat transfer enhancements. In this paper, the ballistic jumping behavior of liquid drops from a superhydrophobic surface is investigated. Powered by the repulsion of the same kind of charges, water drops can jump from the surface. The electrostatic acting time for the jumping of a microliter supercooled drop only takes several milliseconds, even shorter than the time for icing. In addition, one can control the ballistic jumping direction precisely by the relative position above the electrostatic field. The approach offers a facile method that can be used to manipulate the ballistic drop jumping via an electrostatic field, opening the possibility of energy efficient drop detaching techniques in various applications. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. A Knock-in Reporter for a Novel AR-Targeted Therapy

    Science.gov (United States)

    2016-05-01

    AWARD NUMBER: W81XWH-15-1-0049 TITLE: A Knock -in Reporter for a Novel AR-Targeted Therapy PRINCIPAL INVESTIGATOR: Chunhong Yan, Ph.D...5a. CONTRACT NUMBER A Knock -in Reporter for a Novel AR-Targeted Therapy 5b. GRANT NUMBER W81XWH-15-1-0049 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...enhancer. While the knock -in reporter is expected to faithfully reproduce chemical responses of the endogenous AR gene, we carried out a pilot screen

  2. On a calculation of nucleon knock-out cross sections in a collision of relativistic nuclei

    International Nuclear Information System (INIS)

    Goryachev, B.I.; Lin'kova, N.V.

    1985-01-01

    It is shown that in the framework of the two-stage model one can obtain knock-out cross sections of the given number of nucleons from the nucleus-target at a certain number of nucleons knocked out from the nucleus-projectile. The first stage is considered as a fast process of nucleon collisions of interacting nuclei which is completed with knock out of one or several nucleons. The second stage-comparatively slow - is related to de-excitation of nuclei-fragments

  3. Dynamics and stability of directional jumps in the desert locust

    Directory of Open Access Journals (Sweden)

    Omer Gvirsman

    2016-09-01

    Full Text Available Locusts are known for their ability to jump large distances to avoid predation. The jump also serves to launch the adult locust into the air in order to initiate flight. Various aspects of this important behavior have been studied extensively, from muscle physiology and biomechanics, to the energy storage systems involved in powering the jump, and more. Less well understood are the mechanisms participating in control of the jump trajectory. Here we utilise video monitoring and careful analysis of experimental directional jumps by adult desert locusts, together with dynamic computer simulation, in order to understand how the locusts control the direction and elevation of the jump, the residual angular velocities resulting from the jump and the timing of flapping-flight initiation. Our study confirms and expands early findings regarding the instrumental role of the initial body position and orientation. Both real-jump video analysis and simulations based on our expanded dynamical model demonstrate that the initial body coordinates of position (relative to the hind-legs ground-contact points are dominant in predicting the jumps’ azimuth and elevation angles. We also report a strong linear correlation between the jumps’ pitch-angular-velocity and flight initiation timing, such that head downwards rotations lead to earlier wing opening. In addition to offering important insights into the bio-mechanical principles of locust jumping and flight initiation, the findings from this study will be used in designing future prototypes of a bio-inspired miniature jumping robot that will be employed in animal behaviour studies and environmental monitoring applications.

  4. Effects of Isometric Scaling on Vertical Jumping Performance

    Science.gov (United States)

    Bobbert, Maarten F.

    2013-01-01

    Jump height, defined as vertical displacement in the airborne phase, depends on vertical takeoff velocity. For centuries, researchers have speculated on how jump height is affected by body size and many have adhered to what has come to be known as Borelli’s law, which states that jump height does not depend on body size per se. The underlying assumption is that the amount of work produced per kg body mass during the push-off is independent of size. However, if a big body is isometrically downscaled to a small body, the latter requires higher joint angular velocities to achieve a given takeoff velocity and work production will be more impaired by the force-velocity relationship of muscle. In the present study, the effects of pure isometric scaling on vertical jumping performance were investigated using a biologically realistic model of the human musculoskeletal system. The input of the model, muscle stimulation over time, was optimized using jump height as criterion. It was found that when the human model was miniaturized to the size of a mouse lemur, with a mass of about one-thousandth that of a human, jump height dropped from 40 cm to only 6 cm, mainly because of the force-velocity relationship. In reality, mouse lemurs achieve jump heights of about 33 cm. By implication, the unfavourable effects of the small body size of mouse lemurs on jumping performance must be counteracted by favourable effects of morphological and physiological adaptations. The same holds true for other small jumping animals. The simulations for the first time expose and explain the sheer magnitude of the isolated effects of isometric downscaling on jumping performance, to be counteracted by morphological and physiological adaptations. PMID:23936494

  5. Effects of isometric scaling on vertical jumping performance.

    Directory of Open Access Journals (Sweden)

    Maarten F Bobbert

    Full Text Available Jump height, defined as vertical displacement in the airborne phase, depends on vertical takeoff velocity. For centuries, researchers have speculated on how jump height is affected by body size and many have adhered to what has come to be known as Borelli's law, which states that jump height does not depend on body size per se. The underlying assumption is that the amount of work produced per kg body mass during the push-off is independent of size. However, if a big body is isometrically downscaled to a small body, the latter requires higher joint angular velocities to achieve a given takeoff velocity and work production will be more impaired by the force-velocity relationship of muscle. In the present study, the effects of pure isometric scaling on vertical jumping performance were investigated using a biologically realistic model of the human musculoskeletal system. The input of the model, muscle stimulation over time, was optimized using jump height as criterion. It was found that when the human model was miniaturized to the size of a mouse lemur, with a mass of about one-thousandth that of a human, jump height dropped from 40 cm to only 6 cm, mainly because of the force-velocity relationship. In reality, mouse lemurs achieve jump heights of about 33 cm. By implication, the unfavourable effects of the small body size of mouse lemurs on jumping performance must be counteracted by favourable effects of morphological and physiological adaptations. The same holds true for other small jumping animals. The simulations for the first time expose and explain the sheer magnitude of the isolated effects of isometric downscaling on jumping performance, to be counteracted by morphological and physiological adaptations.

  6. Measurement of L3 subshell absorption jump ratios and jump factors for high Z elements using EDXRF technique

    International Nuclear Information System (INIS)

    Kaçal, M.R.

    2014-01-01

    Energy dispersive X-ray fluorescence technique (EDXRF) has been employed for measuring L 3 -subshell absorption jump ratios, r L 3 and jump factors, J L 3 for high Z elements. Jump factors and jump ratios for these elements have been determined by measuring L 3 subshell fluorescence parameters such as L 3 subshell X-ray production cross section σ L 3 , L 3 subshell fluorescence yield, ω L 3 , total L 3 subshell and higher subshells photoionization cross section σ L T . Measurements were performed using a Cd-109 radioactive point source and an Si(Li) detector in direct excitation experimental geometry. Measured values for jump factors and jump ratios have been compared with theoretically calculated and other experimental values. - Highlights: • This paper regards L 3 subshell absorption jump ratios and jump factors using the EDXRF method. • These parameters were measured using a new method. • This method is more useful than other methods which require much effort. • Results are in good agreement with theoretical and experimental values

  7. A Farey tale for N = 4 dyons

    International Nuclear Information System (INIS)

    Murthy, Sameer; Pioline, Boris

    2009-01-01

    We study exponentially suppressed contributions to the degeneracies of extremal black holes. Within Sen's quantum entropy function framework and focusing on extremal black holes with an intermediate AdS 3 region, we identify an infinite family of semi-classical AdS 2 geometries which can contribute effects of order exp(S 0 /c), where S 0 is the Bekenstein-Hawking-Wald entropy and c is an integer greater than one. These solutions lift to the extremal limit of the SL(2,Z) family of BTZ black holes familiar from the 'black hole Farey tail'. We test this understanding in N = 4 string vacua, where exact dyon degeneracies are known to be given by Fourier coefficients of Siegel modular forms. We relate the sum over poles in the Siegel upper half plane to the Farey tail expansion, and derive a 'Farey tale' expansion for the dyon partition function. Mathematically, this provides a (formal) lift from Hilbert modular forms to Siegel modular forms with a pole at the diagonal divisor.

  8. Policy Pathways: A Tale of Renewed Cities

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-08-01

    Transport currently accounts for half of global oil consumption and nearly 20% of world energy use, of which approximately 40% is used in urban transport alone. The IEA expects urban transport energy consumption to double by 2050, despite ongoing vehicle technology and fuel-economy improvements. While increased mobility brings many benefits, the staggering rate of this increase creates new challenges. Urgent energy-efficiency policy attention will be needed to mitigate associated negative noise, air pollution, congestion, climate and economic impacts, all of which can cost countries billions of dollars per year. This report highlights lessons learned and examples of good practice from countries with experience implementing a wide range of measures to improve energy efficiency in urban transport systems. Part of the IEA Policy Pathway series, A Tale of Renewed Cities sets out key steps in planning, implementation, monitoring and evaluation to achieve improved energy efficiency in urban transport systems. The Policy Pathway series aims to help policy makers implement the IEA 25 Energy Efficiency Policy Recommendations.

  9. STABILITY OF LINEAR SYSTEMS WITH MARKOVIAN JUMPS

    Directory of Open Access Journals (Sweden)

    Jorge Enrique Mayta Guillermo

    2016-12-01

    Full Text Available In this work we will analyze the stability of linear systems governed by a Markov chain, this family is known in the specialized literature as linear systems with Markov jumps or by its acronyms in English MJLS as it is denoted in [1]. Linear systems governed by a Markov chain are dynamic systems with abrupt changes. We give some denitions of stability for the MJLS system, where these types of stability are equivalent as long as the state space of the Markov chain is nite. Finally we present a theorem that characterizes the stochastic stability by means of an equation of the Lyapunov type. The result is a generalization of a theorem in classical theory.

  10. Seismic tomography with the reversible jump algorithm

    Science.gov (United States)

    Bodin, Thomas; Sambridge, Malcolm

    2009-09-01

    The reversible jump algorithm is a statistical method for Bayesian inference with a variable number of unknowns. Here, we apply this method to the seismic tomography problem. The approach lets us consider the issue of model parametrization (i.e. the way of discretizing the velocity field) as part of the inversion process. The model is parametrized using Voronoi cells with mobile geometry and number. The size, position and shape of the cells defining the velocity model are directly determined by the data. The inverse problem is tackled within a Bayesian framework and explicit regularization of model parameters is not required. The mobile position and number of cells means that global damping procedures, controlled by an optimal regularization parameter, are avoided. Many velocity models with variable numbers of cells are generated via a transdimensional Markov chain and information is extracted from the ensemble as a whole. As an aid to interpretation we visualize the expected earth model that is obtained via Monte Carlo integration in a straightforward manner. The procedure is particularly adept at imaging rapid changes or discontinuities in wave speed. While each velocity model in the final ensemble consists of many discontinuities at cell boundaries, these are smoothed out in the averaged ensemble solution while those required by the data are reinforced. The ensemble of models can also be used to produce uncertainty estimates and experiments with synthetic data suggest that they represent actual uncertainty surprisingly well. We use the fast marching method in order to iteratively update the ray geometry and account for the non-linearity of the problem. The method is tested here with synthetic data in a 2-D application and compared with a subspace method that is a more standard matrix-based inversion scheme. Preliminary results illustrate the advantages of the reversible jump algorithm. A real data example is also shown where a tomographic image of Rayleigh wave

  11. Direct observation of TALE protein dynamics reveals a two-state search mechanism.

    Science.gov (United States)

    Cuculis, Luke; Abil, Zhanar; Zhao, Huimin; Schroeder, Charles M

    2015-06-01

    Transcription activator-like effector (TALE) proteins are a class of programmable DNA-binding proteins for which the fundamental mechanisms governing the search process are not fully understood. Here we use single-molecule techniques to directly observe TALE search dynamics along DNA templates. We find that TALE proteins are capable of rapid diffusion along DNA using a combination of sliding and hopping behaviour, which suggests that the TALE search process is governed in part by facilitated diffusion. We also observe that TALE proteins exhibit two distinct modes of action during the search process-a search state and a recognition state-facilitated by different subdomains in monomeric TALE proteins. Using TALE truncation mutants, we further demonstrate that the N-terminal region of TALEs is required for the initial non-specific binding and subsequent rapid search along DNA, whereas the central repeat domain is required for transitioning into the site-specific recognition state.

  12. Conformational elasticity can facilitate TALE-DNA recognition.

    Science.gov (United States)

    Lei, Hongxing; Sun, Jiya; Baldwin, Enoch P; Segal, David J; Duan, Yong

    2014-01-01

    Sequence-programmable transcription activator-like effector (TALE) proteins have emerged as a highly efficient tool for genome engineering. Recent crystal structures depict a transition between an open unbound solenoid and more compact DNA-bound solenoid formed by the 34 amino acid repeats. How TALEs switch conformation between these two forms without substantial energetic compensation, and how the repeat-variable di-residues (RVDs) discriminate between the cognate base and other bases still remain unclear. Computational analysis on these two aspects of TALE-DNA interaction mechanism has been conducted in order to achieve a better understanding of the energetics. High elasticity was observed in the molecular dynamics simulations of DNA-free TALE structure that started from the bound conformation where it sampled a wide range of conformations including the experimentally determined apo and bound conformations. This elastic feature was also observed in the simulations starting from the apo form which suggests low free energy barrier between the two conformations and small compensation required upon binding. To analyze binding specificity, we performed free energy calculations of various combinations of RVDs and bases using Poisson-Boltzmann surface area (PBSA) and other approaches. The PBSA calculations indicated that the native RVD-base structures had lower binding free energy than mismatched structures for most of the RVDs examined. Our theoretical analyses provided new insight on the dynamics and energetics of TALE-DNA binding mechanism. © 2014 Elsevier Inc. All rights reserved.

  13. Chimeric TALE recombinases with programmable DNA sequence specificity.

    Science.gov (United States)

    Mercer, Andrew C; Gaj, Thomas; Fuller, Roberta P; Barbas, Carlos F

    2012-11-01

    Site-specific recombinases are powerful tools for genome engineering. Hyperactivated variants of the resolvase/invertase family of serine recombinases function without accessory factors, and thus can be re-targeted to sequences of interest by replacing native DNA-binding domains (DBDs) with engineered zinc-finger proteins (ZFPs). However, imperfect modularity with particular domains, lack of high-affinity binding to all DNA triplets, and difficulty in construction has hindered the widespread adoption of ZFPs in unspecialized laboratories. The discovery of a novel type of DBD in transcription activator-like effector (TALE) proteins from Xanthomonas provides an alternative to ZFPs. Here we describe chimeric TALE recombinases (TALERs): engineered fusions between a hyperactivated catalytic domain from the DNA invertase Gin and an optimized TALE architecture. We use a library of incrementally truncated TALE variants to identify TALER fusions that modify DNA with efficiency and specificity comparable to zinc-finger recombinases in bacterial cells. We also show that TALERs recombine DNA in mammalian cells. The TALER architecture described herein provides a platform for insertion of customized TALE domains, thus significantly expanding the targeting capacity of engineered recombinases and their potential applications in biotechnology and medicine.

  14. A classic fairy tale in the first triennial of the elementary school and the family literacy

    OpenAIRE

    Lukaček, Alenka

    2016-01-01

    A classic fairy tale by a known author is modelled on a folk fairy tale as regards the structure, themes and motifs; however, it mostly differs from it in poetics which gives the fairy tale the character of the author’s narrative” (Haramija, 2012: 17). Fairy tales have been researched since the 19th century and they have been analysed according to numerous theories: folk theory, structuralism theory, literary theory, psychoanalytic theory, sociological theory, feminist theory, and poststructu...

  15. A hard-knock life: the foraging ecology of Cape cormorants amidst ...

    African Journals Online (AJOL)

    A hard-knock life: the foraging ecology of Cape cormorants amidst shifting prey resources and industrial fishing pressure. MH Hamann, D Grémillet, PG Ryan, F Bonadonna, CD van der Lingen, L Pichegru ...

  16. On the knock-out mechanism for the 12C(P,α)9B reaction

    International Nuclear Information System (INIS)

    Hassan, M.Y.M.; Ismail, E.H.; Rabie, A.

    1978-01-01

    The mechanism of the reaction 12 C(P,α) 9 B is studied using zero range distorted wave Born approximation. The knock out mechanism is assumed to represent this reaction both in the forward and backward angles. (orig.) [de

  17. Computer simulation of energy dissipation from near threshold knock-ons in Fe3Al

    International Nuclear Information System (INIS)

    Schade, G.; Leighly, H.P. Jr.; Edwards, D.R.

    1976-01-01

    A computer program has been developed and used to model a series of knock-ons near the damage energy threshold in a micro-crystallite of the ordered alloy Fe 3 Al. The primary paths of energy removal from the knock-on site were found to be along the [100] and [111] directions by means of focusing type collision chains. The relative importance of either direction as an energy removal path varied with the initial knock-on direction and also changed with time during the course of the knock-on event. The time rate of energy removal was found to be greatest in the [111] direction due to the shorter interatomic distances between atoms along this direction

  18. Terpineol as a novel octane booster for extending the knock limit of gasoline

    KAUST Repository

    Vallinayagam, R.; Vedharaj, S.; Naser, Nimal; Roberts, William L.; Dibble, Robert W.; Sarathy, Mani

    2016-01-01

    Improving the octane number of gasoline offers the potential of improved engine combustion, as it permits spark timing advancement without engine knock. This study proposes the use of terpineol as an octane booster for gasoline in a spark ignited

  19. Knock-Outs, Stick-Outs, Cut-Outs: Clipping Paths Separate Objects from Background.

    Science.gov (United States)

    Wilson, Bradley

    1998-01-01

    Outlines a six-step process that allows computer operators, using Photoshop software, to create "knock-outs" to precisely define the path that will serve to separate the object from the background. (SR)

  20. When Your Back Hurts: Don't Let Back Pain Knock You Flat

    Science.gov (United States)

    ... Your Back Hurts Don’t Let Back Pain Knock You Flat En español Send us your comments ... Complementary Health Approaches Halt the Hurt! References The SPORT Value Compass: Do the Extra Costs of Undergoing ...

  1. A COMPARISON OF PAIRS FIGURE SKATERS IN REPEATED JUMPS

    Directory of Open Access Journals (Sweden)

    William A. Sands

    2012-03-01

    Full Text Available Trends in pairs figure skating have shown that increasingly difficult jumps have become an essential aspect of high-level performance, especially in the latter part of a competitive program. We compared a repeated jump power index in a 60 s repeated jump test to determine the relationship of repeated jump test to competitive rank and to measure 2D hip, knee, and ankle angles and angular velocities at 0, 20, 40, and 60 s. Eighteen National Team Pairs Figure Skaters performed a 60 s repeated jump test on a large switch-mat with timing of flight and ground durations and digital video recording. Each 60-s period was divided into 6, 10-s intervals, with power indexes (W/kg calculated for each 10-s interval. Power index by 10-s interval repeated measures ANOVAs (RMANOVA showed that males exceeded females at all intervals, and the highest power index interval was during 10 to 20 s for both sexes. RMANOVAs of angles and angular velocities showed main effects for time only. Power index and jumping techniques among figure skaters showed rapid and steady declines over the test duration. Power index can predict approximately 50% of competitive rank variance, and sex differences in jumping technique were rare

  2. Validity of a jump training apparatus using Wii Balance Board.

    Science.gov (United States)

    Yamamoto, Keizo; Matsuzawa, Mamoru

    2013-05-01

    The dynamic quantification of jump ability is useful for sports performance evaluation. We developed a force measurement system using the Wii Balance Board (WBB). This study was conducted to validate the system in comparison with a laboratory-grade force plate (FP). For a static validation, weights of 10-180kg were put progressively on the WBB put on the FP. The vertical component of the ground reaction force (vGRF) was measured using both devices and compared. For the dynamic validation, 10 subjects without lower limb pathology participated in the study and performed vertical jumping twice on the WBB on the FP. The range of analysis was set from the landing after the first jump to taking off of the second jump. The peak values during the landing phase and jumping phase were obtained and the force-time integral (force impulse) was measured. The relations of the values measured using each device were compared using Pearson's correlation coefficient test and Bland-Altman plots (BAP). Significant correlation (P<.01, r=.99) was found between the values of both devices in the static and the dynamic test. Examination of the BAP revealed a proportion error in the landing phase and showed no relation in the jumping phase between the difference and the mean in the dynamic test. The WBB detects the vGRF in the jumping phase with high precision. Copyright © 2012 Elsevier B.V. All rights reserved.

  3. Temperature dependence of knocking-out cross sections of a bound atom from the lattice site

    International Nuclear Information System (INIS)

    Zhdanov, S.K.; Pletnev, V.V.

    1981-01-01

    The total cross section of atom knocking-out from the lattice site is calculated with the atom binding in the lattice site taken into account. The intermediate case of atom being preads over the bottom of a spherical potential well is considered (the case of intermediate temperatures). Thus the target temperature parameter enters the equation for the total cross section of atom knocking-out

  4. Writing and Retelling Multiple Ethnographic Tales of a Soup Kitchen for the Homeless.

    Science.gov (United States)

    Miller, Dana L.; Creswell, John W.; Olander, Lisa

    An ethnographic study narrated three tales about a soup kitchen for the homeless and the near-homeless. To provide a cultural, ethnographic analysis, and share fieldwork experiences the study began with realist and confessional tales. These two tales emerged from the initial writing and presenting of the soup kitchen ethnography to qualitative…

  5. Optimizing the Distribution of Leg Muscles for Vertical Jumping.

    Directory of Open Access Journals (Sweden)

    Jeremy D Wong

    Full Text Available A goal of biomechanics and motor control is to understand the design of the human musculoskeletal system. Here we investigated human functional morphology by making predictions about the muscle volume distribution that is optimal for a specific motor task. We examined a well-studied and relatively simple human movement, vertical jumping. We investigated how high a human could jump if muscle volume were optimized for jumping, and determined how the optimal parameters improve performance. We used a four-link inverted pendulum model of human vertical jumping actuated by Hill-type muscles, that well-approximates skilled human performance. We optimized muscle volume by allowing the cross-sectional area and muscle fiber optimum length to be changed for each muscle, while maintaining constant total muscle volume. We observed, perhaps surprisingly, that the reference model, based on human anthropometric data, is relatively good for vertical jumping; it achieves 90% of the jump height predicted by a model with muscles designed specifically for jumping. Alteration of cross-sectional areas-which determine the maximum force deliverable by the muscles-constitutes the majority of improvement to jump height. The optimal distribution results in large vastus, gastrocnemius and hamstrings muscles that deliver more work, while producing a kinematic pattern essentially identical to the reference model. Work output is increased by removing muscle from rectus femoris, which cannot do work on the skeleton given its moment arm at the hip and the joint excursions during push-off. The gluteus composes a disproportionate amount of muscle volume and jump height is improved by moving it to other muscles. This approach represents a way to test hypotheses about optimal human functional morphology. Future studies may extend this approach to address other morphological questions in ethological tasks such as locomotion, and feature other sets of parameters such as properties of

  6. Optimizing the Distribution of Leg Muscles for Vertical Jumping

    Science.gov (United States)

    Wong, Jeremy D.; Bobbert, Maarten F.; van Soest, Arthur J.; Gribble, Paul L.; Kistemaker, Dinant A.

    2016-01-01

    A goal of biomechanics and motor control is to understand the design of the human musculoskeletal system. Here we investigated human functional morphology by making predictions about the muscle volume distribution that is optimal for a specific motor task. We examined a well-studied and relatively simple human movement, vertical jumping. We investigated how high a human could jump if muscle volume were optimized for jumping, and determined how the optimal parameters improve performance. We used a four-link inverted pendulum model of human vertical jumping actuated by Hill-type muscles, that well-approximates skilled human performance. We optimized muscle volume by allowing the cross-sectional area and muscle fiber optimum length to be changed for each muscle, while maintaining constant total muscle volume. We observed, perhaps surprisingly, that the reference model, based on human anthropometric data, is relatively good for vertical jumping; it achieves 90% of the jump height predicted by a model with muscles designed specifically for jumping. Alteration of cross-sectional areas—which determine the maximum force deliverable by the muscles—constitutes the majority of improvement to jump height. The optimal distribution results in large vastus, gastrocnemius and hamstrings muscles that deliver more work, while producing a kinematic pattern essentially identical to the reference model. Work output is increased by removing muscle from rectus femoris, which cannot do work on the skeleton given its moment arm at the hip and the joint excursions during push-off. The gluteus composes a disproportionate amount of muscle volume and jump height is improved by moving it to other muscles. This approach represents a way to test hypotheses about optimal human functional morphology. Future studies may extend this approach to address other morphological questions in ethological tasks such as locomotion, and feature other sets of parameters such as properties of the skeletal

  7. Propulsion efficiency and imposed flow fields of a copepod jump.

    Science.gov (United States)

    Jiang, Houshuo; Kiørboe, Thomas

    2011-02-01

    Pelagic copepods jump to relocate, to attack prey and to escape predators. However, there is a price to be paid for these jumps in terms of their energy costs and the hydrodynamic signals they generate to rheotactic predators. Using observed kinematics of various types of jumps, we computed the imposed flow fields and associated energetics of jumps by means of computational fluid dynamics simulations by modeling the copepod as a self-propelled body. The computational fluid dynamics simulation was validated by particle image velocimetry data. The flow field generated by a repositioning jump quickly evolves into two counter-rotating viscous vortex rings that are near mirror image of one another, one in the wake and one around the body of the copepod; this near symmetrical flow may provide hydrodynamic camouflage because it contains no information about the position of the copepod prey within the flow structure. The flow field associated with an escape jump sequence also includes two dominant vortex structures: one leading wake vortex generated as a result of the first jump and one around the body, but between these two vortex structures is an elongated, long-lasting flow trail with flow velocity vectors pointing towards the copepod; such a flow field may inform the predator of the whereabouts of the escaping copepod prey. High Froude propulsion efficiency (0.94-0.98) was obtained for individual power stroke durations of all simulated jumps. This is unusual for small aquatic organisms but is caused by the rapidity and impulsiveness of the jump that allows only a low-cost viscous wake vortex to travel backwards.

  8. Numerical simulations of katabatic jumps in coats land, Antartica

    Science.gov (United States)

    Yu, Ye; Cai, Xiaoming; King, John C.; Renfrew, Ian A.

    A non-hydrostatic numerical model, the Regional Atmospheric Modeling System (RAMS), has been used to investigate the development of katabatic jumps in Coats Land, Antarctica. In the control run with a 5 m s-1downslope directed initial wind, a katabatic jump develops near the foot of the idealized slope. The jump is manifested as a rapid deceleration of the downslope flow and a change from supercritical to subcritical flow, in a hydraulic sense, i.e., the Froude number (Fr) of the flow changes from Fr > 1 to Fr> 1. Results from sensitivity experiments show that an increase in the upstream flow rate strengthens the jump, while an increase in the downstream inversion-layer depth results in a retreat of the jump. Hydraulic theory and Bernoulli''s theorem have been used to explain the surface pressure change across the jump. It is found that hydraulic theory always underestimates the surface pressure change, while Bernoulli''s theorem provides a satisfactory estimation. An analysis of the downs balance for the katabatic jump indicates that the important forces are those related to the pressure gradient, advection and, to a lesser extent, the turbulent momentum divergence. The development of katabatic jumps can be divided into two phases. In phase I, the t gradient force is nearly balanced by advection, while in phase II, the pressure gradient force is counterbalanced by turbulent momentum divergence. The upslope pressure gradient force associated with a pool of cold air over the ice shelf facilitates the formation of the katabatic jump.

  9. Sensitivity of dual fuel engine combustion and knocking limits to gaseous fuel composition

    Energy Technology Data Exchange (ETDEWEB)

    Selim, M.Y.E. [United Arab Emirates University, Al-Ain (United Arab Emirates). Dept. of Mechanical Engineering

    2004-02-01

    Combustion noise, knock and ignition limits data are measured and presented for a dual fuel engine running on dual fuels of Diesel and three gaseous fuels separately. The gaseous fuels used are liquefied petroleum gas, pure methane and compressed natural gas mixture. The maximum pressure rise rate during combustion is presented as a measure of combustion noise, and the knocking and ignition limits are presented as torque output at the onset of knocking and ignition failure. Experimental investigation on the dual fuel engine revealed the noise generated from combustion, knocking and ignition limits for all gases at different design and operating conditions. A Ricardo E6 Diesel version engine is converted to run on dual fuel of Diesel and the tested gaseous fuel and is used throughout the work. The engine is fully computerized, and the cylinder pressure data, crank angle data and engine operating variables are stored in a PC for off line analysis. The effects of engine speeds, loads, pilot injection angle, pilot fuel quantity and compression ratio on combustion noise, knocking torque, thermal efficiency and maximum pressure are examined for the dual engine running on the three gaseous fuels separately. The combustion noise, knocking and ignition limits are found to relate to the type of gaseous fuels and to the engine design and operating parameters. (author)

  10. Highly efficient CRISPR/HDR-mediated knock-in for mouse embryonic stem cells and zygotes.

    Science.gov (United States)

    Wang, Bangmei; Li, Kunyu; Wang, Amy; Reiser, Michelle; Saunders, Thom; Lockey, Richard F; Wang, Jia-Wang

    2015-10-01

    The clustered regularly interspaced short palindromic repeat (CRISPR) gene editing technique, based on the non-homologous end-joining (NHEJ) repair pathway, has been used to generate gene knock-outs with variable sizes of small insertion/deletions with high efficiency. More precise genome editing, either the insertion or deletion of a desired fragment, can be done by combining the homology-directed-repair (HDR) pathway with CRISPR cleavage. However, HDR-mediated gene knock-in experiments are typically inefficient, and there have been no reports of successful gene knock-in with DNA fragments larger than 4 kb. Here, we describe the targeted insertion of large DNA fragments (7.4 and 5.8 kb) into the genomes of mouse embryonic stem (ES) cells and zygotes, respectively, using the CRISPR/HDR technique without NHEJ inhibitors. Our data show that CRISPR/HDR without NHEJ inhibitors can result in highly efficient gene knock-in, equivalent to CRISPR/HDR with NHEJ inhibitors. Although NHEJ is the dominant repair pathway associated with CRISPR-mediated double-strand breaks (DSBs), and biallelic gene knock-ins are common, NHEJ and biallelic gene knock-ins were not detected. Our results demonstrate that efficient targeted insertion of large DNA fragments without NHEJ inhibitors is possible, a result that should stimulate interest in understanding the mechanisms of high efficiency CRISPR targeting in general.

  11. Motor Deficits and Cerebellar Atrophy in Elovl5 Knock Out Mice.

    Science.gov (United States)

    Hoxha, Eriola; Gabriele, Rebecca M C; Balbo, Ilaria; Ravera, Francesco; Masante, Linda; Zambelli, Vanessa; Albergo, Cristian; Mitro, Nico; Caruso, Donatella; Di Gregorio, Eleonora; Brusco, Alfredo; Borroni, Barbara; Tempia, Filippo

    2017-01-01

    Spino-Cerebellar-Ataxia type 38 (SCA38) is caused by missense mutations in the very long chain fatty acid elongase 5 gene, ELOVL5 . The main clinical findings in this disease are ataxia, hyposmia and cerebellar atrophy. Mice in which Elovl5 has been knocked out represent a model of the loss of function hypothesis of SCA38. In agreement with this hypothesis, Elovl5 knock out mice reproduced the main symptoms of patients, motor deficits at the beam balance test and hyposmia. The cerebellar cortex of Elovl5 knock out mice showed a reduction of thickness of the molecular layer, already detectable at 6 months of age, confirmed at 12 and 18 months. The total perimeter length of the Purkinje cell (PC) layer was also reduced in Elovl5 knock out mice. Since Elovl5 transcripts are expressed by PCs, whose dendrites are a major component of the molecular layer, we hypothesized that an alteration of their dendrites might be responsible for the reduced thickness of this layer. Reconstruction of the dendritic tree of biocytin-filled PCs, followed by Sholl analysis, showed that the distribution of distal dendrites was significantly reduced in Elovl5 knock out mice. Dendritic spine density was conserved. These results suggest that Elovl5 knock out mice recapitulate SCA38 symptoms and that their cerebellar atrophy is due, at least in part, to a reduced extension of PC dendritic arborization.

  12. Determination of knock characteristics in spark ignition engines: an approach based on ensemble empirical mode decomposition

    International Nuclear Information System (INIS)

    Li, Ning; Liang, Caiping; Yang, Jianguo; Zhou, Rui

    2016-01-01

    Knock is one of the major constraints to improve the performance and thermal efficiency of spark ignition (SI) engines. It can also result in severe permanent engine damage under certain operating conditions. Based on the ensemble empirical mode decomposition (EEMD), this paper proposes a new approach to determine the knock characteristics in SI engines. By adding a uniformly distributed and finite white Gaussian noise, the EEMD can preserve signal continuity in different scales and therefore alleviates the mode-mixing problem occurring in the classic empirical mode decomposition (EMD). The feasibilities of applying the EEMD to detect the knock signatures of a test SI engine via the pressure signal measured from combustion chamber and the vibration signal measured from cylinder head are investigated. Experimental results show that the EEMD-based method is able to detect the knock signatures from both the pressure signal and vibration signal, even in initial stage of knock. Finally, by comparing the application results with those obtained by short-time Fourier transform (STFT), Wigner–Ville distribution (WVD) and discrete wavelet transform (DWT), the superiority of the EEMD method in determining knock characteristics is demonstrated. (paper)

  13. Sensitivity of dual fuel engine combustion and knocking limits to gaseous fuel composition

    International Nuclear Information System (INIS)

    Selim, Mohamed Y.E.

    2004-01-01

    Combustion noise, knock and ignition limits data are measured and presented for a dual fuel engine running on dual fuels of Diesel and three gaseous fuels separately. The gaseous fuels used are liquefied petroleum gas, pure methane and compressed natural gas mixture. The maximum pressure rise rate during combustion is presented as a measure of combustion noise, and the knocking and ignition limits are presented as torque output at the onset of knocking and ignition failure. Experimental investigation on the dual fuel engine revealed the noise generated from combustion, knocking and ignition limits for all gases at different design and operating conditions. A Ricardo E6 Diesel version engine is converted to run on dual fuel of Diesel and the tested gaseous fuel and is used throughout the work. The engine is fully computerized, and the cylinder pressure data, crank angle data and engine operating variables are stored in a PC for off line analysis. The effects of engine speeds, loads, pilot injection angle, pilot fuel quantity and compression ratio on combustion noise, knocking torque, thermal efficiency and maximum pressure are examined for the dual engine running on the three gaseous fuels separately. The combustion noise, knocking and ignition limits are found to relate to the type of gaseous fuels and to the engine design and operating parameters

  14. Live visualization of genomic loci with BiFC-TALE.

    Science.gov (United States)

    Hu, Huan; Zhang, Hongmin; Wang, Sheng; Ding, Miao; An, Hui; Hou, Yingping; Yang, Xiaojing; Wei, Wensheng; Sun, Yujie; Tang, Chao

    2017-01-11

    Tracking the dynamics of genomic loci is important for understanding the mechanisms of fundamental intracellular processes. However, fluorescent labeling and imaging of such loci in live cells have been challenging. One of the major reasons is the low signal-to-background ratio (SBR) of images mainly caused by the background fluorescence from diffuse full-length fluorescent proteins (FPs) in the living nucleus, hampering the application of live cell genomic labeling methods. Here, combining bimolecular fluorescence complementation (BiFC) and transcription activator-like effector (TALE) technologies, we developed a novel method for labeling genomic loci (BiFC-TALE), which largely reduces the background fluorescence level. Using BiFC-TALE, we demonstrated a significantly improved SBR by imaging telomeres and centromeres in living cells in comparison with the methods using full-length FP.

  15. Jump-Down Performance Alterations after Space Flight

    Science.gov (United States)

    Reschke, M. F.; Kofman, I. S.; Cerisano, J. M.; Fisher, E. A.; Peters, B. T.; Miller, C. A.; Harm, D. L.; Bloomberg, J. J.

    2011-01-01

    INTRODUCTION: Successful jump performance requires functional coordination of visual, vestibular, and somatosensory systems, which are affected by prolonged exposure to microgravity. Astronauts returning from space flight exhibit impaired ability to coordinate effective landing strategies when jumping from a platform to the ground. This study compares jump strategies used by astronauts before and after flight, changes to those strategies within a test session, and recoveries in jump-down performance parameters across several postflight test sessions. These data were obtained as part of an ongoing interdisciplinary study (Functional Task Test, FTT) designed to evaluate both astronaut postflight functional performance and related physiological changes. METHODS: Seven astronauts from short-duration (Shuttle) and three from long-duration (International Space Station) flights performed 3 two-footed jumps from a platform 30 cm high onto a force plate that measured the ground reaction forces and center-of-pressure displacement from the landings. Neuromuscular activation data were collected from the medial gastrocnemius and anterior tibialis of both legs using surface electromyography electrodes. Two load cells in the platform measured the load exerted by each foot during the takeoff phase of the jump. Data were collected in 2 preflight sessions, on landing day (Shuttle only), and 1, 6, and 30 days after flight. RESULTS: Postural settling time was significantly increased on the first postflight test session and many of the astronauts tested were unable to maintain balance on their first jump landing but recovered by the third jump, showing a learning progression in which performance improvements could be attributed to adjustments in takeoff or landing strategy. Jump strategy changes were evident in reduced air time (time between takeoff and landing) and also in increased asymmetry in foot latencies on takeoff. CONCLUSIONS: The test results revealed significant decrements

  16. Temperature Jump Pyrolysis Studies of RP 2 Fuel

    Science.gov (United States)

    2017-01-09

    Briefing Charts 3. DATES COVERED (From - To) 15 December 2016 – 11 January 2017 4. TITLE AND SUBTITLE Temperature Jump Pyrolysis Studies of RP-2 Fuel...Rev. 8- 98) Prescribed by ANSI Std. 239.18 1 TEMPERATURE JUMP PYROLYSIS STUDIES OF RP-2 FUEL Owen Pryor1, Steven D. Chambreau2, Ghanshyam L...17026 7 Temperature Jump Pyrolysis at AFRL Edwards Rapid heating of a metal filament at a rate of 600 – 800 K/s, and the set temperature is held for

  17. Effects of kettlebell training on postural coordination and jump performance

    DEFF Research Database (Denmark)

    Jay, Kenneth; Jakobsen, Markus Due; Sundstrup, Emil

    2013-01-01

    ABSTRACT: The aim of this study was to investigate the effectiveness of a worksite intervention using kettlebell training to improve postural reactions to perturbation and jump performance.This single-blind randomized controlled trial involved 40 adults (n=40) from occupations with a high....... The outcome measures were postural reactions to sudden perturbation and maximal countermovement jump height.Compared to the control group, the training group significant decreased stopping time following perturbation (-109ms, 95% CI [-196:-21]). Jump height increased significantly in the training group (1.5cm...

  18. Diarylethene microcrystals make directional jumps upon ultraviolet irradiation

    International Nuclear Information System (INIS)

    Colombier, I.; Spagnoli, S.; Corval, A.; Baldeck, P. L.; Giraud, M.; Leaustic, A.; Yu, P.; Irie, M.

    2007-01-01

    Microcrystals of a diarylethene {1,2-bis[5 ' -methyl-2 ' -(2 '' -pyridyl)thiazolyl]perfluorocyclo-pentene } undergo jumps upon photoirradiation. These photochromic crystals present molecular structural changes upon irradiation with ultraviolet light because of reversible photocyclization reactions. When the energy absorbed by crystals reaches about 10 μJ, the uniaxial stress induced in the crystal lattice relaxes through directional jumps. If one prevents crystals from jumping, then parallel, equidistant cracks appear on crystal surfaces. These photomechanical effects could result from a Grinfeld surface instability

  19. Developing an Enhanced Lightning Jump Algorithm for Operational Use

    Science.gov (United States)

    Schultz, Christopher J.; Petersen, Walter A.; Carey, Lawrence D.

    2009-01-01

    Overall Goals: 1. Build on the lightning jump framework set through previous studies. 2. Understand what typically occurs in nonsevere convection with respect to increases in lightning. 3. Ultimately develop a lightning jump algorithm for use on the Geostationary Lightning Mapper (GLM). 4 Lightning jump algorithm configurations were developed (2(sigma), 3(sigma), Threshold 10 and Threshold 8). 5 algorithms were tested on a population of 47 nonsevere and 38 severe thunderstorms. Results indicate that the 2(sigma) algorithm performed best over the entire thunderstorm sample set with a POD of 87%, a far of 35%, a CSI of 59% and a HSS of 75%.

  20. The Perpetual American Put Option for Jump-Diffusions

    OpenAIRE

    Aase, Knut K.

    2010-01-01

    -This is the author's version of the article"The Perpetual American Put Option for Jump-Diffusions" Energy Systems pp 493-507. We solve a specific optimal stopping problem with an infinite time horizon, when the state variable follows a jump-diffusion. The novelty of the paper is related to the inclusion of a jump component in this stochastic process. Under certain conditions, our solution can be interpreted as the price of an American perpetual put option. We characterize the continuation...

  1. Mechanism design and optimization of a bionic kangaroo jumping robot

    Science.gov (United States)

    Zhang, Y. H.; Zheng, L.; Ge, W. J.; Zou, Z. H.

    2018-03-01

    Hopping robots have broad application prospects in the fields of military reconnaissance, field search or life rescue. However, current hopping robots still face the problems of weak jumping ability and load bearing. Inspired by the jumping of kangaroo, we design a Kangaroo hopping robot “Zbot”, which has two degrees of freedom and three joints. The geared five-bar mechanism is used to decouple the knee and ankle joints of the robot. In order to get a bionic performance, the coupling mechanism parameters are optimized. The simulation and experiments show that the robot has an excellent jumping ability and load capacity.

  2. Jumps in the curve of creep of the stainless steel

    International Nuclear Information System (INIS)

    Silveira, T.L.; Monteiro, S.N.

    The discontinuous flow observed in creep for several stainless steels at certain streels conditions in the interval of temperatures from 550 to 800 0 C has been investigated. This phenomenon appears as repetitive jumps with strain and stress increments that could be evaluated and related to the tests variables. The stress increment increases, consistently, with the stress level at the jump. This Δo versus sigma relation is due to strain aging effects and is a consequence of the variation of the stain rate during the deformation band propagation which causes the jump [pt

  3. Rate Theory for Correlated Processes: Double Jumps in Adatom Diffusion

    DEFF Research Database (Denmark)

    Jacobsen, J.; Jacobsen, Karsten Wedel; Sethna, J.

    1997-01-01

    We study the rate of activated motion over multiple barriers, in particular the correlated double jump of an adatom diffusing on a missing-row reconstructed platinum (110) surface. We develop a transition path theory, showing that the activation energy is given by the minimum-energy trajectory...... which succeeds in the double jump. We explicitly calculate this trajectory within an effective-medium molecular dynamics simulation. A cusp in the acceptance region leads to a root T prefactor for the activated rate of double jumps. Theory and numerical results agree....

  4. MEASURE FOR MEASURE: A THRICE TOLD TALE

    Directory of Open Access Journals (Sweden)

    HALIMAH MOHAMED ALI

    2009-01-01

    Full Text Available This paper argues that Measure for Measure is a difficult play to perform because it has problematic themes, especially the theme of sexuality, that clash with the way of life and thinking of contemporary society. As such, any director who chooses to stage it must consider these difficulties and how to present them in a natural manner without making the audience feel that the whole production is contrived. The directors of the two major productions discussed in this paper tried their best to present a Measure for Measure that would be acceptable to the modern society. It is evident that there are many interpretations of the Duke and Isabella's characters and also of Isabella's reaction to the Duke's proposal at the end of the play. It can be concluded that no interpretation is wrong because each actor or director brings with him his own reading of the play, and every reading has been influenced by other performances and textual criticisms. Since Measure for Measure is a thematically rich play, it should not be confined to a single interpretation. The different performances of Measure for Measure have proven that theatre is experimental as well as ageless. Because it is a brilliant play with a myriad of interpretations, Measure for Measure will not cease to be a favourite for directors in times to come. It is not wrong to predict that fans of Shakespeare in general and of Measure for Measure in particular can look forward to many more productions.For experienced Shakespeare observers all performances are thrice-told tales. The perceiving eye absorbs the performance even as the mind's eye attends to the text. Both are augmented by the inner ear buzzing with those other voices, both critical and dramatic, carried by the observer into the theatre.(Crowl, Samuel 1992: 3

  5. Change in Counter movement Jump Strategy by Varying Jump Height Based on Simplified Framework for Center of Mass Mechanics

    International Nuclear Information System (INIS)

    Kim, Seyoung

    2017-01-01

    In this study, we investigated how a jumping strategy changes with an increase in the vertical jump height for a resultant ground reaction force (GRF) vector. We expected that the resultant force vector between two sequential motion phases (i.e., countermovement and push-off) of the counter movement jump would significantly change with the vertical jump height to take advantage of the resulting supportive force (i.e., an initial push-off force larger than the body weight) through the counter movement phase. Nine healthy young subjects were instructed to jump straight up to five different height levels ranging from 191 cm to 221 cm, and the kinematic and kinetic data were obtained in regular trials. The results showed that a lower center of mass position and larger resultant force vector were clearly observed in a higher jump, implying that the counter movement strategy changed with the vertical jump height to prepare for sufficient joint deviation and obtain a force advantage for larger push-off work.

  6. Change in Counter movement Jump Strategy by Varying Jump Height Based on Simplified Framework for Center of Mass Mechanics

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seyoung [Korea Institute of Machinery and Materials(KIMM), Daejeon (Korea, Republic of)

    2017-04-15

    In this study, we investigated how a jumping strategy changes with an increase in the vertical jump height for a resultant ground reaction force (GRF) vector. We expected that the resultant force vector between two sequential motion phases (i.e., countermovement and push-off) of the counter movement jump would significantly change with the vertical jump height to take advantage of the resulting supportive force (i.e., an initial push-off force larger than the body weight) through the counter movement phase. Nine healthy young subjects were instructed to jump straight up to five different height levels ranging from 191 cm to 221 cm, and the kinematic and kinetic data were obtained in regular trials. The results showed that a lower center of mass position and larger resultant force vector were clearly observed in a higher jump, implying that the counter movement strategy changed with the vertical jump height to prepare for sufficient joint deviation and obtain a force advantage for larger push-off work.

  7. Predicting lower body power from vertical jump prediction equations for loaded jump squats at different intensities in men and women.

    Science.gov (United States)

    Wright, Glenn A; Pustina, Andrew A; Mikat, Richard P; Kernozek, Thomas W

    2012-03-01

    The purpose of this study was to determine the efficacy of estimating peak lower body power from a maximal jump squat using 3 different vertical jump prediction equations. Sixty physically active college students (30 men, 30 women) performed jump squats with a weighted bar's applied load of 20, 40, and 60% of body mass across the shoulders. Each jump squat was simultaneously monitored using a force plate and a contact mat. Peak power (PP) was calculated using vertical ground reaction force from the force plate data. Commonly used equations requiring body mass and vertical jump height to estimate PP were applied such that the system mass (mass of body + applied load) was substituted for body mass. Jump height was determined from flight time as measured with a contact mat during a maximal jump squat. Estimations of PP (PP(est)) for each load and for each prediction equation were compared with criterion PP values from a force plate (PP(FP)). The PP(est) values had high test-retest reliability and were strongly correlated to PP(FP) in both men and women at all relative loads. However, only the Harman equation accurately predicted PP(FP) at all relative loads. It can therefore be concluded that the Harman equation may be used to estimate PP of a loaded jump squat knowing the system mass and peak jump height when more precise (and expensive) measurement equipment is unavailable. Further, high reliability and correlation with criterion values suggest that serial assessment of power production across training periods could be used for relative assessment of change by either of the prediction equations used in this study.

  8. A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8.

    Science.gov (United States)

    Bouhy, Delphine; Juneja, Manisha; Katona, Istvan; Holmgren, Anne; Asselbergh, Bob; De Winter, Vicky; Hochepied, Tino; Goossens, Steven; Haigh, Jody J; Libert, Claude; Ceuterick-de Groote, Chantal; Irobi, Joy; Weis, Joachim; Timmerman, Vincent

    2018-01-01

    Mutations in the small heat shock protein B8 gene (HSPB8/HSP22) have been associated with distal hereditary motor neuropathy, Charcot-Marie-Tooth disease, and recently distal myopathy. It is so far not clear how mutant HSPB8 induces the neuronal and muscular phenotypes and if a common pathogenesis lies behind these diseases. Growing evidence points towards a role of HSPB8 in chaperone-associated autophagy, which has been shown to be a determinant for the clearance of poly-glutamine aggregates in neurodegenerative diseases but also for the maintenance of skeletal muscle myofibrils. To test this hypothesis and better dissect the pathomechanism of mutant HSPB8, we generated a new transgenic mouse model leading to the expression of the mutant protein (knock-in lines) or the loss-of-function (functional knock-out lines) of the endogenous protein Hspb8. While the homozygous knock-in mice developed motor deficits associated with degeneration of peripheral nerves and severe muscle atrophy corroborating patient data, homozygous knock-out mice had locomotor performances equivalent to those of wild-type animals. The distal skeletal muscles of the post-symptomatic homozygous knock-in displayed Z-disk disorganisation, granulofilamentous material accumulation along with Hspb8, αB-crystallin (HSPB5/CRYAB), and desmin aggregates. The presence of the aggregates correlated with reduced markers of effective autophagy. The sciatic nerve of the homozygous knock-in mice was characterized by low autophagy potential in pre-symptomatic and Hspb8 aggregates in post-symptomatic animals. On the other hand, the sciatic nerve of the homozygous knock-out mice presented a normal morphology and their distal muscle displayed accumulation of abnormal mitochondria but intact myofiber and Z-line organisation. Our data, therefore, suggest that toxic gain-of-function of mutant Hspb8 aggregates is a major contributor to the peripheral neuropathy and the myopathy. In addition, mutant Hspb8 induces

  9. [Effects of Reactive Jump Training in Handball Players Regarding Jump Height and Power Development in the Triceps Surae Muscle].

    Science.gov (United States)

    Rensing, N; Westermann, A; Möller, D; von Piekartz, H

    2015-12-01

    Studies have shown changes in the technical and physical demands in modern handball. The game has increased considerably in speed, power and dynamics. Jump training has, therefore, become ever more important in the training of the athletes. These developments contribute to the fact that handball is now one of the most injury-prone types of sport, with the lower extremities being most frequently affected. Reactive jump training is not only used in training by now, but also increasingly in injury prevention. The aim of this study was to investigate the effectiveness of reactive jump training with handball players. 21 regional league handball players were randomly divided into an intervention group (n = 12) and a control group (n = 9). The intervention group completed a six-week reactive jump training programme while the control group went through a non-specific training programme. Jump height (squat and counter movement jump), isokinetic and isometric maximum power as well as muscle activity served as measuring parameters. A comparison of the intervention and control groups revealed that the reactive jump training led to significant improvements in jump height. The isometric and isokinetic maximum power measurements and the electromyographic activities of the triceps surae muscle demonstrated an improvement in the values within the intervention group. However, this improvement was not significant compared with the control group. Likewise both jumps correlated with the muscle activity of the soleus muscle as shown by electromyography. A moderate correlation was noticed between the isokinetic maximum power measurement and the electromyographic activity of the soleus and gastrocnemius medialis muscles. Furthermore, the correlations of the isometric and isokinetic maximum power meas-urements resulted in a strong correlation coefficient. This study revealed a significant increase in jump height after reactive jump training. There was no significant difference in

  10. “Souls of the ancestor that knock us out” and other tales. A qualitative study to identify demand-side factors influencing malaria case management in Cambodia

    Directory of Open Access Journals (Sweden)

    O’Connell Kathryn A

    2012-10-01

    Full Text Available Abstract Background Appropriate case management of suspected malaria in Cambodia is critical given anti-malarial drug resistance in the region. Improving diagnosis and the use of recommended malarial treatments is a challenge in Cambodia where self-treatment and usage of drug cocktails is widespread, a notable difference from malaria treatment seeking in other countries. This qualitative study adds to the limited evidence base on Cambodian practices, aiming to understand the demand-side factors influencing treatment-seeking behaviour, including the types of home treatments, perceptions of cocktail medicines and reasons for diagnostic testing. The findings may help guide intervention design. Methods The study used in-depth interviews (IDIs (N = 16 and focus group discussions (FGDs (N = 12 with Cambodian adults from malaria-endemic areas who had experienced malaria fever in the previous two weeks. Data were analysed using NVivo software. Results Findings suggest that Cambodians initially treat suspected malaria at home with home remedies and traditional medicines. When seeking treatment outside the home, respondents frequently reported receiving a cocktail of medicines from trusted providers. Cocktails are perceived as less expensive and more effective than full-course, pre-packaged medicines. Barriers to diagnostic testing include a belief in the ability to self-diagnose based on symptoms, cost and reliance on providers to recommend a test. Factors that facilitate testing include recommendation by trusted providers and a belief that anti-malarial treatment for illnesses other than malaria can be harmful. Conclusions Treatment-seeking behaviour for malaria in Cambodia is complex, driven by cultural norms, practicalities and episode-related factors. Effective malaria treatment programmes will benefit from interventions and communication materials that leverage these demand-side factors, promoting prompt visits to facilities for suspected malaria and challenging patients’ misconceptions about the effectiveness of cocktails. Given the importance of the patient-provider interaction and the pivotal role that providers play in ensuring the delivery of appropriate malaria care, future research and interventions should also focus on the supply side factors influencing provider behaviour.

  11. A tale of TALE, PREP1, PBX1, and MEIS1: Interconnections and competition in cancer.

    Science.gov (United States)

    Blasi, Francesco; Bruckmann, Chiara; Penkov, Dmitry; Dardaei, Leila

    2017-05-01

    We report the latest structural information on PREP1 tumor suppressor, the specific "oncogene" and "tumor suppressive" signatures of MEIS1 and PREP1, the molecular rules regulating PREP1 and MEIS1 binding to DNA, and how these can change depending on the interaction with PBX1, cell-type, neoplastic transformation, and intracellular concentration. As both PREP1 and MEIS1 interact with PBX1 they functionally compete with each other. PREP1, PBX1, and MEIS1 TALE-class homeodomain transcription factors act in an interdependent and integrated way in experimental tumorigenesis. We also pool together the plethora of data available in human cancer databanks and connect them with the available molecular information. The emerging picture suggests that a similarly basic approach might be used to better dissect and define other oncogenes and suppressors and better understand human cancer. © 2017 The Authors. BioEssays Published by WILEY Periodicals, Inc.

  12. Detection of Dew-Point by substantial Raman Band Frequency Jumps (A new Method)

    DEFF Research Database (Denmark)

    Hansen, Susanne Brunsgaard; Berg, Rolf W.; Stenby, Erling Halfdan

    Detection of Dew-Point by substantial Raman Band Frequency Jumps (A new Method). See poster at http://www.kemi.dtu.dk/~ajo/rolf/jumps.pdf......Detection of Dew-Point by substantial Raman Band Frequency Jumps (A new Method). See poster at http://www.kemi.dtu.dk/~ajo/rolf/jumps.pdf...

  13. Queen of Peace Nursing Home, Churchfield, Knock, Mayo.

    LENUS (Irish Health Repository)

    Teljeur, Conor

    2010-01-01

    BACKGROUND: Estimating the supply of GPs into the future is important in forecasting shortages. The lengthy training process for medicine means that adjusting supply to meet demand in a timely fashion is problematic. This study uses Ireland as a case study to determine the future demand and supply of GPs and to assess the potential impact of several possible interventions to address future shortages. METHODS: Demand was estimated by applying GP visit rates by age and sex to national population projections. Supply was modelled using a range of parameters derived from two national surveys of GPs. A stochastic modelling approach was adopted to determine the probable future supply of GPs. Four policy interventions were tested: increasing vocational training places; recruiting GPs from abroad; incentivising later retirement; increasing nurse substitution to enable practice nurses to deliver more services. RESULTS: Relative to most other European countries, Ireland has few GPs per capita. Ireland has an ageing population and demand is estimated to increase by 19% by 2021. Without intervention, the supply of GPs will be 5.7% less than required in 2021. Increasing training places will enable supply to meet demand but only after 2019. Recruiting GPs from overseas will enable supply to meet demand continuously if the number recruited is approximately 0.8 per cent of the current workforce per annum. Later retirement has only a short-term impact. Nurse substitution can enable supply to meet demand but only if large numbers of practice nurses are recruited and allowed to deliver a wide range of GP services. CONCLUSIONS: A significant shortfall in GP supply is predicted for Ireland unless recruitment is increased. The shortfall will have numerous knock-on effects including price increases, longer waiting lists and an increased burden on hospitals. Increasing training places will not provide an adequate response to future shortages. Foreign recruitment has ethical considerations

  14. Quantum jumps are more quantum than quantum diffusion

    International Nuclear Information System (INIS)

    Daryanoosh, Shakib; M Wiseman, Howard

    2014-01-01

    It was recently argued (Wiseman and Gambetta 2012 Phys. Rev. Lett. 108 220402) that the stochastic dynamics (jumps or diffusion) of an open quantum system are not inherent to the system, but rather depend on the existence and nature of a distant detector. The proposed experimental tests involved homodyne detection, giving rise to quantum diffusion, and required efficiencies η of well over 50%. Here we prove that this requirement (η>0.5) is universal for diffusive-type detection, even if the system is coupled to multiple baths. However, this no-go theorem does not apply to quantum jumps, and we propose a test involving a qubit with jump-type detectors, with a threshold efficiency of only 37%. That is, quantum jumps are ‘more quantum’, and open the way to practical experimental tests. Our scheme involves a novel sort of adaptive monitoring scheme on a system coupled to two baths. (paper)

  15. Hydraulic jump and Bernoulli equation in nonlinear shallow water model

    Science.gov (United States)

    Sun, Wen-Yih

    2018-06-01

    A shallow water model was applied to study the hydraulic jump and Bernoulli equation across the jump. On a flat terrain, when a supercritical flow plunges into a subcritical flow, discontinuity develops on velocity and Bernoulli function across the jump. The shock generated by the obstacle may propagate downstream and upstream. The latter reflected from the inflow boundary, moves downstream and leaves the domain. Before the reflected wave reaching the obstacle, the short-term integration (i.e., quasi-steady) simulations agree with Houghton and Kasahara's results, which may have unphysical complex solutions. The quasi-steady flow is quickly disturbed by the reflected wave, finally, flow reaches steady and becomes critical without complex solutions. The results also indicate that Bernoulli function is discontinuous but the potential of mass flux remains constant across the jump. The latter can be used to predict velocity/height in a steady flow.

  16. A quasi-static treatment of multiple phase jumps

    International Nuclear Information System (INIS)

    Englman, R; Vertesi, T

    2005-01-01

    A quasi-static, WKB-type treatment accounts well for the surprising phase jumps that are odd multiples of π (1 + 2n)π, found as a molecular system journeys adiabatically in a configuration coordinate plane that contains several points of degeneracies. We show that the number n in the phase jump is an integer close to |n'| that appears in the expression for the complex wavefunction amplitude valid (approximately) for times close to when the phase jump occurs: -δT + 2πθ+πn'sinδT -i[1-πn'cosδT](δT is a shifted and rescaled trajectory-time parameter and θ is a numerical fraction (<1) which depends on the adiabaticity of the motion.) The central quantity n' is local, i.e., depends on the values of the parameters in the Hamiltonian only at the beginning of the trajectory and at the instant of the phase jump

  17. Trading price jump clusters in foreign exchange markets

    Czech Academy of Sciences Publication Activity Database

    Novotný, Jan; Petrov, D.; Urga, G.

    2015-01-01

    Roč. 24, June (2015), s. 66-92 ISSN 1386-4181 Institutional support: PRVOUK-P23 Keywords : price jumps * foreign exchange markets * trading Subject RIV: AH - Economics Impact factor: 1.726, year: 2015

  18. The fluid dynamics of swimming by jumping in copepods

    DEFF Research Database (Denmark)

    Jiang, Houshuo; Kiørboe, Thomas

    2011-01-01

    Copepods swim either continuously by vibrating their feeding appendages or erratically by repeatedly beating their swimming legs resulting in a series of small jumps. The two swimming modes generate different hydrodynamic disturbances and therefore expose the swimmers differently to rheotactic...... limited and temporally ephemeral owing to jump-impulsiveness and viscous decay. In contrast, continuous steady swimming generates two well-extended long-lasting momentum jets both in front of and behind the swimmer, as suggested by the well-known steady stresslet model. Based on the observed jump-swimming...... kinematics of a small copepod Oithona davisae, we further showed that jump-swimming produces a hydrodynamic disturbance with much smaller spatial extension and shorter temporal duration than that produced by a same-size copepod cruising steadily at the same average translating velocity. Hence, small copepods...

  19. Hiding information in open auctions with jump bids

    Czech Academy of Sciences Publication Activity Database

    Ettinger, D.; Michelucci, Fabio

    2016-01-01

    Roč. 126, č. 594 (2016), s. 1484-1502 ISSN 0013-0133 Institutional support: RVO:67985998 Keywords : hiding information * open auctions * jump bids Subject RIV: AH - Economics Impact factor: 2.608, year: 2016

  20. METRIC TESTS CHARACTERISTIC FOR ESTIMATING JUMPING FOR VOLLEYBALL PLAYERS

    Directory of Open Access Journals (Sweden)

    Toplica Stojanović

    2008-08-01

    Full Text Available With goal to establish metric tests characteristics for estimating jumping for volleyball players, it was organized a pilot research on pattern of 23 volleyball players from cadet team and 23 students from high-school. For needs of this research four tests are valid for estimation, jump in block with left and right leg and jump in spike with left and right leg. Each test has been taken three times, so that we could with test-re test method determine their reliability, and with factor analysis their validity. Data were processed by multivariate analysis (item analysis, factor analysis from statistical package „Statistica 6.0 for windows“. On the results of research and discussion we can say that the tests had high coefficient of reliability, as well as factor validity, and these tests can be used to estimate jumping for volleyball players.

  1. Jump diffusion models and the evolution of financial prices

    International Nuclear Information System (INIS)

    Figueiredo, Annibal; Castro, Marcio T. de; Silva, Sergio da; Gleria, Iram

    2011-01-01

    We analyze a stochastic model to describe the evolution of financial prices. We consider the stochastic term as a sum of the Wiener noise and a jump process. We point to the effects of the jumps on the return time evolution, a central concern of the econophysics literature. The presence of jumps suggests that the process can be described by an infinitely divisible characteristic function belonging to the De Finetti class. We then extend the De Finetti functions to a generalized nonlinear model and show the model to be capable of explaining return behavior. -- Highlights: → We analyze a stochastic model to describe the evolution of financial prices. → The stochastic term is considered as a sum of the Wiener noise and a jump process. → The process can be described by an infinitely divisible characteristic function belonging to the De Finetti class. → We extend the De Finetti functions to a generalized nonlinear model.

  2. Hiding information in open auctions with jump bids

    Czech Academy of Sciences Publication Activity Database

    Ettinger, D.; Michelucci, Fabio

    2016-01-01

    Roč. 126, č. 594 (2016), s. 1484-1502 ISSN 0013-0133 Institutional support: PRVOUK-P23 Keywords : hiding information * open auctions * jump bids Subject RIV: AH - Economics Impact factor: 2.608, year: 2016

  3. The exit-time problem for a Markov jump process

    Science.gov (United States)

    Burch, N.; D'Elia, M.; Lehoucq, R. B.

    2014-12-01

    The purpose of this paper is to consider the exit-time problem for a finite-range Markov jump process, i.e, the distance the particle can jump is bounded independent of its location. Such jump diffusions are expedient models for anomalous transport exhibiting super-diffusion or nonstandard normal diffusion. We refer to the associated deterministic equation as a volume-constrained nonlocal diffusion equation. The volume constraint is the nonlocal analogue of a boundary condition necessary to demonstrate that the nonlocal diffusion equation is well-posed and is consistent with the jump process. A critical aspect of the analysis is a variational formulation and a recently developed nonlocal vector calculus. This calculus allows us to pose nonlocal backward and forward Kolmogorov equations, the former equation granting the various moments of the exit-time distribution.

  4. Impulsive evolution inclusions with infinite delay and multivalued jumps

    Directory of Open Access Journals (Sweden)

    Mouffak Benchohra

    2012-08-01

    Full Text Available In this paper we prove the existence of a mild solution for a class of impulsive semilinear evolution differential inclusions with infinite delay and multivalued jumps in a Banach space.

  5. Swarm algorithms with chaotic jumps for optimization of multimodal functions

    Science.gov (United States)

    Krohling, Renato A.; Mendel, Eduardo; Campos, Mauro

    2011-11-01

    In this article, the use of some well-known versions of particle swarm optimization (PSO) namely the canonical PSO, the bare bones PSO (BBPSO) and the fully informed particle swarm (FIPS) is investigated on multimodal optimization problems. A hybrid approach which consists of swarm algorithms combined with a jump strategy in order to escape from local optima is developed and tested. The jump strategy is based on the chaotic logistic map. The hybrid algorithm was tested for all three versions of PSO and simulation results show that the addition of the jump strategy improves the performance of swarm algorithms for most of the investigated optimization problems. Comparison with the off-the-shelf PSO with local topology (l best model) has also been performed and indicates the superior performance of the standard PSO with chaotic jump over the standard both using local topology (l best model).

  6. Generation of dTALEs and Libraries of Synthetic TALE-Activated Promoters for Engineering of Gene Regulatory Networks in Plants.

    Science.gov (United States)

    Schreiber, Tom; Tissier, Alain

    2017-01-01

    Transcription factors with programmable DNA-binding specificity constitute valuable tools for the design of orthogonal gene regulatory networks for synthetic biology. Transcription activator-like effectors (TALEs), as natural transcription regulators, were used to design, build, and test libraries of synthetic TALE-activated promoters (STAPs) that show a broad range of expression levels in plants. In this chapter, we present protocols for the construction of artificial TALEs and corresponding STAPs.

  7. Spinal column damage from water ski jumping

    International Nuclear Information System (INIS)

    Horne, J.; Cockshott, W.P.; Shannon, H.S.

    1987-01-01

    We conducted a radiographic survey of 117 competitive water ski jumpers to determine whether this sport can cause spinal column damage and, if so, whether damage is more likely to occur in those who participate during the period of spinal growth and development (age 15 years or younger). We found a high prevalence of two types of abnormality: Scheuermann (adolescent) spondylodystrophy (present in 26% of the skiers) and vertebral body wedging (present in 34%). The prevalence of adolescent spondylodystrophy increased with the number of years of participation in the sport before age 15 years or less. Of those in this age group who had skied for 5 years or more, 57 showed adolescent spondylodystrophy; of those in the same age group who had skied for 9 years or more, 100% were affected. Wedged vertebrae increased as time of participation increased, regardless of the age at which exposure began. We conclude that competitive water ski jumping may damage the spinal column and that consideration should be given to regulating this sport, particularly for children. (orig.)

  8. Spinal column damage from water ski jumping.

    Science.gov (United States)

    Horne, J; Cockshott, W P; Shannon, H S

    1987-01-01

    We conducted a radiographic survey of 117 competitive water ski jumpers to determine whether this sport can cause spinal column damage and, if so, whether damage is more likely to occur in those who participate during the period of spinal growth and development (age 15 years or younger). We found a high prevalence of two types of abnormality: Scheuermann (adolescent) spondylodystrophy (present in 26% of the skiers) and vertebral body wedging (present in 34%). The prevalence of adolescent spondylodystrophy increased with the number of years of participation in the sport before age 15 years or less. Of those in this age group who had skied for 5 years or more, 57 showed adolescent spondylodystrophy; of those in the same age group who had skied for 9 years or more, 100% were affected. Wedged vertebrae increased as time of participation increased, regardless of the age at which exposure began. We conclude that competitive water ski jumping may damage the spinal column and that consideration should be given to regulating this sport, particularly for children.

  9. Why do oil prices jump (or fall)?

    International Nuclear Information System (INIS)

    Wirl, Franz

    2008-01-01

    This paper discusses theories that can explain the zig-zags of oil prices in general and in particular the recent jump. More precisely, the following explanations are discussed: Homo oeconomicus (pure profit maximization if demand is dynamic and convex), price reaction function (price increases and respectively declines depend on capacity utilization), cartelization contingent on output or revenues of which the latter can lead to backward bending supply segments and multiple equilibria, statistical descriptions (mean reversion), homo politicus, i.e., arguments for price hikes that are rational (Public Choice) despite the (long-run) economic loss. Finally two approaches are presented that emphasize demand uncertainty: one extending the above-mentioned dynamic demand framework and the other considers a dynamic game of non-competitive suppliers with lumpy investments. Summing up, a demand shock seems to be the most suitable explanation of today's high prices (indeed a shock given that International Energy Agency (IEA) and Department of Energy (DoE) were promising just a couple of years ago that we are going to have lots of oil at low prices), while others and in particular politics have surprisingly little or no explanatory power. (author)

  10. Ethics in radiology: wait lists queue jumping.

    Science.gov (United States)

    Cunningham, Natalie; Reid, Lynette; MacSwain, Sarah; Clarke, James R

    2013-08-01

    Education in ethics is a requirement for all Royal College residency training programs as laid out in the General Standards of Accreditation for residency programs in Canada. The ethical challenges that face radiologists in clinical practice are often different from those that face other physicians, because the nature of the physician-patient interaction is unlike that of many other specialties. Ethics education for radiologists and radiology residents will benefit from the development of teaching materials and resources that focus on the issues that are specific to the specialty. This article is intended to serve as an educational resource for radiology training programs to facilitate teaching ethics to residents and also as a continuing medical education resource for practicing radiologists. In an environment of limited health care resources, radiologists are frequently asked to expedite imaging studies for patients and, in some respects, act as gatekeepers for specialty care. The issues of wait lists, queue jumping, and balancing the needs of individuals and society are explored from the perspective of a radiologist. Copyright © 2013 Canadian Association of Radiologists. Published by Elsevier Inc. All rights reserved.

  11. Vortex jump behavior in coupled nanomagnetic heterostructures

    International Nuclear Information System (INIS)

    Zhang, S.; Phatak, C.; Petford-Long, A. K.; Heinonen, O.

    2014-01-01

    The spin configuration and magnetic behavior in patterned nanostructures can be controlled by manipulating the interplay between the competing energy terms. This in turn requires fundamental knowledge of the magnetic interactions at the local nanometer scale. Here, we report on the spin structure and magnetization behavior of patterned discs containing exchange coupled ferromagnetic layers with additional exchange bias to an antiferromagnetic layer. The magnetization reversal was explored by direct local visualization of the domain behavior using in-situ Lorentz transmission electron microscopy, from which quantitative magnetic induction maps were reconstructed. The roles of the main competing energy terms were elucidated and the reversal mechanism was identified as a coupled phenomenon of incoherent rotation in the exchange-biased layer and localized vortex nucleation and discontinuous propagation in the free layer, including an anomalous jump in the trajectory. The observations were supported by micromagnetic simulations and modeled phase shift simulations. The work presented here provides fundamental insights into opportunities for macroscopic control of the energy landscape of magnetic heterostructures for functional applications

  12. Spinal column damage from water ski jumping

    Energy Technology Data Exchange (ETDEWEB)

    Horne, J.; Cockshott, W.P.; Shannon, H.S.

    1987-11-01

    We conducted a radiographic survey of 117 competitive water ski jumpers to determine whether this sport can cause spinal column damage and, if so, whether damage is more likely to occur in those who participate during the period of spinal growth and development (age 15 years or younger). We found a high prevalence of two types of abnormality: Scheuermann (adolescent) spondylodystrophy (present in 26% of the skiers) and vertebral body wedging (present in 34%). The prevalence of adolescent spondylodystrophy increased with the number of years of participation in the sport before age 15 years or less. Of those in this age group who had skied for 5 years or more, 57 showed adolescent spondylodystrophy; of those in the same age group who had skied for 9 years or more, 100% were affected. Wedged vertebrae increased as time of participation increased, regardless of the age at which exposure began. We conclude that competitive water ski jumping may damage the spinal column and that consideration should be given to regulating this sport, particularly for children. (orig.)

  13. Vortex jump behavior in coupled nanomagnetic heterostructures

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, S.; Phatak, C., E-mail: cd@anl.gov [Materials Science Division, Argonne National Laboratory, 9700 S. Cass Avenue, Argonne, Illinois 60439 (United States); Petford-Long, A. K. [Materials Science Division, Argonne National Laboratory, 9700 S. Cass Avenue, Argonne, Illinois 60439 (United States); Department of Materials Science and Engineering, Northwestern University, 2220 Campus Drive, Evanston, Illinois 60208 (United States); Heinonen, O. [Materials Science Division, Argonne National Laboratory, 9700 S. Cass Avenue, Argonne, Illinois 60439 (United States); Department of Physics and Astronomy, Northwestern University, 2145 Sheridan Rd, Evanston, Illinois 60208-3112 (United States)

    2014-11-24

    The spin configuration and magnetic behavior in patterned nanostructures can be controlled by manipulating the interplay between the competing energy terms. This in turn requires fundamental knowledge of the magnetic interactions at the local nanometer scale. Here, we report on the spin structure and magnetization behavior of patterned discs containing exchange coupled ferromagnetic layers with additional exchange bias to an antiferromagnetic layer. The magnetization reversal was explored by direct local visualization of the domain behavior using in-situ Lorentz transmission electron microscopy, from which quantitative magnetic induction maps were reconstructed. The roles of the main competing energy terms were elucidated and the reversal mechanism was identified as a coupled phenomenon of incoherent rotation in the exchange-biased layer and localized vortex nucleation and discontinuous propagation in the free layer, including an anomalous jump in the trajectory. The observations were supported by micromagnetic simulations and modeled phase shift simulations. The work presented here provides fundamental insights into opportunities for macroscopic control of the energy landscape of magnetic heterostructures for functional applications.

  14. A jumping shape memory alloy under heat.

    Science.gov (United States)

    Yang, Shuiyuan; Omori, Toshihiro; Wang, Cuiping; Liu, Yong; Nagasako, Makoto; Ruan, Jingjing; Kainuma, Ryosuke; Ishida, Kiyohito; Liu, Xingjun

    2016-02-16

    Shape memory alloys are typical temperature-sensitive metallic functional materials due to superelasticity and shape recovery characteristics. The conventional shape memory effect involves the formation and deformation of thermally induced martensite and its reverse transformation. The shape recovery process usually takes place over a temperature range, showing relatively low temperature-sensitivity. Here we report novel Cu-Al-Fe-Mn shape memory alloys. Their stress-strain and shape recovery behaviors are clearly different from the conventional shape memory alloys. In this study, although the Cu-12.2Al-4.3Fe-6.6Mn and Cu-12.9Al-3.8Fe-5.6Mn alloys possess predominantly L2(1) parent before deformation, the 2H martensite stress-induced from L2(1) parent could be retained after unloading. Furthermore, their shape recovery response is extremely temperature-sensitive, in which a giant residual strain of about 9% recovers instantly and completely during heating. At the same time, the phenomenon of the jumping of the sample occurs. It is originated from the instantaneous completion of the reverse transformation of the stabilized 2H martensite. This novel Cu-Al-Fe-Mn shape memory alloys have great potentials as new temperature-sensitive functional materials.

  15. PERBANDINGAN JUMP SHOOT DENGAN AWALAN DAN TANPA AWALAN TERHADAP PENINGKATAN KETEPATAN SHOOTING DALAM PERMAINAN BOLABASKET

    OpenAIRE

    I Gusti Ngurah Agung Cahya Prananta; N. Adiputra; I P G Adiatmika

    2015-01-01

    The effectiveness of  jump-shoot technique step jump shoot and still jump shoot in a game is still questionable,  because many different assumptions arise. One opinion stated that step jump shoot was more effective and the other stated that and still jump shoot was more efective. Therefore it is necessary to do research on the analysis of the results of step jump shoot and and still jump shoot to improve the accuracy of shooting in a basketball. The experimental research had been conducted on...

  16. Transition-energy crossing with a γt-jump

    International Nuclear Information System (INIS)

    Wei, Jie; Peggs, S.

    1994-01-01

    Expressions for the minimum size and speed of a transition-energy (γ t -) jump needed to diminish the chromatic non-linear effect, the self-field mismatch, and the microwave instabilities in the Relativistic Heavy Ion Collider (RHIC) are obtained. A γ t -jump of 0.8 units is needed to be performed within 60 ms in order to achieve a ''clean'' transition crossing

  17. Local uncontrollability for affine control systems with jumps

    Science.gov (United States)

    Treanţă, Savin

    2017-09-01

    This paper investigates affine control systems with jumps for which the ideal If(g1, …, gm) generated by the drift vector field f in the Lie algebra L(f, g1, …, gm) can be imbedded as a kernel of a linear first-order partial differential equation. It will lead us to uncontrollable affine control systems with jumps for which the corresponding reachable sets are included in explicitly described differentiable manifolds.

  18. Hypohydration Reduces Vertical Ground Reaction Impulse But Not Jump Height

    Science.gov (United States)

    2010-01-01

    height, provided that muscle contractile function remains normal, because gravitational and inertial resistance to jumping are pro- portional to body...testing, anthropometric and fitness measurements were made to characterize the study population. Peak aerobic power (VO2peak) was determined using an...determinations. All volunteers performed between 3 and 5 practice days of vertical jump testing to reduce training and learning effects. Practice

  19. Knee Muscular Control During Jump Landing in Multidirections

    OpenAIRE

    Sinsurin, Komsak; Vachalathiti, Roongtiwa; Jalayondeja, Wattana; Limroongreungrat, Weerawat

    2016-01-01

    Background Jump landing is a complex movement in sports. While competing and practicing, athletes frequently perform multi-planar jump landing. Anticipatory muscle activity could influence the amount of knee flexion and prepare the knee for dynamic weight bearing such as landing tasks. Objectives The aim of the present study was to examine knee muscle function and knee flexion excursion as athletes naturally performed multi-direct...

  20. Seismic interpretation of the triangle zone at Jumping Pound, Alberta

    Energy Technology Data Exchange (ETDEWEB)

    Slotboom, R. T. [Amerada Hess Canada Ltd., Calgary, AB (Canada); Lawton, D. C.; Spratt, D. A. [Calgary Univ., AB (Canada). Dept. of Geology and Geophysics

    1996-06-01

    The triangle zone at Jumping Point, Alberta was characterized using seismic survey data as a NW-SE-trending antiformal stack of thrust sheets involving Cretaceous rocks that have been wedged into the foreland between two detachments. Three major thrust sheets of Lower and Upper Cretaceous strata have been stacked to form the main extremity of the wedge. The structure is tightly folded at Jumping Point, and broadens northwest along the strike. 13 refs., 8 figs.

  1. Kinematic structure at the early flight position in ski jumping.

    Science.gov (United States)

    Vodičar, Janez; Coh, Milan; Jošt, Bojan

    2012-12-01

    The purpose of our research was to establish the variability of correlation between the length of the jumps and selected multi-item kinematic variables (n=9) in the early flight phase technique of ski jumping. This study was conducted on a sample of elite Slovenian ski jumpers (N=29) who participated in the experiment on a jumping hill in Hinterzarten, Germany (HS95m) on the 20(th) of August, 2008. The highest and most significant correlations (p=0.01) with the length of the ski jump were found in the multi-item variable height of flying, which was also expressed with the highest level of stability of the explained total variance (TV) on the first factor (TV=69.13%). The most important characteristic of the aerodynamic aspect of early flight was the variable angle between the body chord and the horizontal axis with significantly high correlations (pjump. Only two more variables, the angle between the upper body and the horizontal plane (TV=53.69%), and the angle between left ski and left leg (TV=50.13%), had an explained common variance on the first factor greater than 50% of total variance. The results indicated that some kinematic parameters of ski jumping early flight technique were more important for success considering the length of the jump.

  2. Discharge regimes and density jumps in a helicon plasma source

    International Nuclear Information System (INIS)

    Shinohara, S.; Yonekura, K.

    1999-01-01

    A high density plasma source using a helicon wave is becoming very attractive in plasma processing and confinement devices. In the previous work, the characteristics of this wave and plasma performance with diameters of 5 and 45 cm have been studied, and the helicon wave was only observed after the density jump. Recently, density jumps from the low to high electron densities with a level of 10 13 cm -3 were investigated by changing the antenna wavenumber spectrum, and the obtained results were compared with the inductively coupled plasma (ICP). However, the mechanisms of density jumps and plasma production are still open questions to be answered. Here, the authors try to investigate the discharge regimes and density jumps in a helicon plasma source, by changing the antenna wavenumber spectrum. For he case of the parallel current directions in the antenna, where the low wavenumber spectrum part is large, the density jump was observed with the low RF input power of P in < 300 W regardless of the magnetic field. On the other hand, for the case of the opposite directions, where the low wavenumber spectrum part is small, the threshold power to obtain the jump became high with the increase in the magnetic field. This can be understood from the dispersion relation of the helicon wave. The wave structures and the dispersion relations in the discharge modes will be also shown

  3. Kinetic asymmetries between forward and drop jump landing tasks

    Directory of Open Access Journals (Sweden)

    Morgana Alves de Britto

    2015-12-01

    Full Text Available DOI: http://dx.doi.org/10.5007/1980-0037.2015v17n6p661   Landing asymmetry is a risk factor for knee anterior cruciate ligament injury. The aim of this study was to identify kinetic asymmetries in healthy recreational athletes performing different jump-landing techniques. Twelve recreational athletes engaged in regular training underwent kinetic evaluation using two 3D force plates and were analyzed for: (a three-dimensional peak forces, (b time to peak vertical force, and (c initial phase asymmetries. All data were collected during performance of unilateral and bilateral trials of forward and drop jump tasks. Forward jump-landing tasks elicited greater kinetic asymmetry than drop-landing tasks. Regardless of jump-landing technique, the preferred leg experienced higher forces than the non-preferred leg. The initial landing phase showed more kinetic asymmetries than the later phase when peak vertical forces occur. It was concluded that when screening athletes for kinetic asymmetries that may predispose them to injury, forward jump-landing tasks and the early landing phase might show more kinetic asymmetries than drop jump-landing tasks and the late landing phase, respectively.

  4. the Modeling of Hydraulic Jump Generated Partially on Sloping Apron

    Directory of Open Access Journals (Sweden)

    Shaker Abdulatif Jalil

    2017-12-01

    Full Text Available Modeling aims to characterize system behavior and achieve simulation close as possible of the reality. The rapid energy exchange in supercritical flow to generate quiet or subcritical flow in hydraulic jump phenomenon is important in design of hydraulic structures. Experimental and numerical modeling is done on type B hydraulic jump which starts first on sloping bed and its end on horizontal bed.  Four different apron slopes are used, for each one of these slopes the jump is generated on different locations by controlling the tail water depth.  Modelling validation is based on 120 experimental runs which they show that there is reliability. The air volume fraction which creates in through hydraulic jump varied between 0.18 and 0.28. While the energy exchanges process take place within 6.6, 6.1, 5.8, 5.5 of the average relative jump height for apron slopes of 0.18, 0.14, 0.10, 0.07 respectively. Within the limitations of this study, mathematical prediction model for relative hydraulic jump height is suggested.The model having an acceptable coefficient of determination.

  5. Fairy-tale planet: creative science writing for children

    Science.gov (United States)

    Lanza, Tiziana; D'Addezio, Giuliana

    2017-04-01

    During public events organized by our Institute sometimes we have predisposed a corner to entertain primary school children with fairy-tales about the planet. In that occasion we realized that even if children could take part in other activities more in fashion such as laboratories, theatre performances, exhibits, they were very attracted by fairy tales, such an "ancient" tradition. This year within the projects "alternanza scuola-lavoro" we are planning to involve also the students of the secondary schools to learn themselves how to animate a fairy-tale corner for children. The "alternanza scuola lavoro" (interchange school/work) has been recently introduced in the Italian school as a methodology for implementing the second cycle teaching. The general purpose is to ensure that 15 to 18 years old students, beside the access to basic knowledge, can acquire skills in the employment and real work environments experiencing other teaching methods based both on knowledge and know-how. We will then start a new adventure by investigating what will be the best way to introduce children to creative science writing for the planet. The aim would be that of creating a format suitable for children either for writing all together a planet fairy-tale in class, or individually. The final goal is to raise awareness about the environmental problems by stimulating in scholars their own creativity.

  6. Computational Drafting of Plot Structures for Russian Folk Tales.

    Science.gov (United States)

    Gervás, Pablo

    The plots of stories are known to follow general patterns in terms of their overall structure. This was the basic tenet of structuralist approaches to narratology. Vladimir Propp proposed a procedure for the generation of new tales based on his semi-formal description of the structure of Russian folk tales. This is one of the first existing instances of a creative process described procedurally. The present paper revisits Propp's morphology to build a system that generates instances of Russian folk tales. Propp's view of the folk tale as a rigid sequence of character functions is employed as a plot driver, and some issues that Propp declared relevant but did not explore in detail-such as long-range dependencies between functions or the importance of endings-are given computational shape in the context of a broader architecture that captures all the aspects discussed by Propp. A set of simple evaluation metrics for the resulting outputs is defined inspired on Propp's formalism. The potential of the resulting system for providing a creative story generation system is discussed, and possible lines of future work are discussed.

  7. Tell-Tale Signs: Reflection towards the Acquisition of Academic ...

    African Journals Online (AJOL)

    Tell-Tale Signs: Reflection towards the Acquisition of Academic Discourses as Second Languages. ... Stellenbosch Papers in Linguistics ... After enrolling in a sign language course, we – lecturers teaching academic discourses – decided to explore this phenomenon and determine the implications for pedagogical practice.

  8. The Lobster Tale: An Exercise in Critical Thinking

    Science.gov (United States)

    Stepanovich, Paul L.

    2009-01-01

    Professors in management and business are encouraged to incorporate critical thinking as an objective in their courses. "The Lobster Tale" provides an opportunity to engage students in various levels of critical thinking, ranging from a relatively superficial reading to an examination of the deeper, often hidden issues. Using the foundations of…

  9. Fairy Tale and Trauma in Toni Morrison's Home

    NARCIS (Netherlands)

    Visser, Irene

    2016-01-01

    The literary work of Toni Morrison is famous for its rich intertexuality, interweaving narrative, contemporary history, and tales and motifs from oral storytelling traditions. Her tenth novel, Home (2013), is no exception. It contains disturbing and dark narratives of childhood abuse, war trauma,

  10. Generation of TALE-Based Designer Epigenome Modifiers.

    Science.gov (United States)

    Nitsch, Sandra; Mussolino, Claudio

    2018-01-01

    Manipulation of gene expression can be facilitated by editing the genome or the epigenome. Precise genome editing is traditionally achieved by using designer nucleases which are generally exploited to eliminate a specific gene product. Upon the introduction of a site-specific DNA double-strand break (DSB) by the nuclease, endogenous DSB repair mechanisms are in turn harnessed to induce DNA sequence changes that can result in target gene inactivation. Minimal off-target effects can be obtained by endowing designer nucleases with the highly specific DNA-binding domain (DBD) derived from transcription activator-like effectors (TALEs). In contrast, epigenome editing allows gene expression control without inducing changes in the DNA sequence by specifically altering epigenetic marks, as histone tails modifications or DNA methylation patterns within promoter or enhancer regions. Importantly, this approach allows both up- and downregulation of the target gene expression, and the effect is generally reversible. TALE-based designer epigenome modifiers combine the high specificity of TALE-derived DBDs with the power of epigenetic modifier domains to induce fast and long-lasting changes in the epigenetic landscape of a target gene and control its expression. Here we provide a detailed description for the generation of TALE-based designer epigenome modifiers and of a suitable reporter cell line to easily monitor their activity.

  11. From DNA binding to transcriptional activation: Is the TALE complete?

    Science.gov (United States)

    Bobola, Nicoletta

    2017-09-04

    How transcription factors (TFs) control enhancer and promoter functions to effect changes in gene expression is an important question. In this issue, Hau et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201701154) show that the TALE TF MEIS recruits the histone modifier PARP1/ARTD1 at promoters to decompact chromatin and activate transcription. © 2017 Bobola.

  12. A Salamander Tale: Effective Exhibits and Attitude Change

    Science.gov (United States)

    Rollins, Jeffrey; Watson, Sunnie Lee

    2017-01-01

    Little information exists regarding intention behind the design and development of Extension outreach and educational exhibits. An evaluation of response to the exhibit "A Salamander Tale" indicates that the methods used to develop the exhibit resulted in an effective way to present information to an adult audience. Survey questions were…

  13. Libraries of Synthetic TALE-Activated Promoters: Methods and Applications.

    Science.gov (United States)

    Schreiber, T; Tissier, A

    2016-01-01

    The discovery of proteins with programmable DNA-binding specificities triggered a whole array of applications in synthetic biology, including genome editing, regulation of transcription, and epigenetic modifications. Among those, transcription activator-like effectors (TALEs) due to their natural function as transcription regulators, are especially well-suited for the development of orthogonal systems for the control of gene expression. We describe here the construction and testing of libraries of synthetic TALE-activated promoters which are under the control of a single TALE with a given DNA-binding specificity. These libraries consist of a fixed DNA-binding element for the TALE, a TATA box, and variable sequences of 19 bases upstream and 43 bases downstream of the DNA-binding element. These libraries were cloned using a Golden Gate cloning strategy making them usable as standard parts in a modular cloning system. The broad range of promoter activities detected and the versatility of these promoter libraries make them valuable tools for applications in the fine-tuning of expression in metabolic engineering projects or in the design and implementation of regulatory circuits. © 2016 Elsevier Inc. All rights reserved.

  14. The TALE face of Hox proteins in animal evolution.

    Science.gov (United States)

    Merabet, Samir; Galliot, Brigitte

    2015-01-01

    Hox genes are major regulators of embryonic development. One of their most conserved functions is to coordinate the formation of specific body structures along the anterior-posterior (AP) axis in Bilateria. This architectural role was at the basis of several morphological innovations across bilaterian evolution. In this review, we traced the origin of the Hox patterning system by considering the partnership with PBC and Meis proteins. PBC and Meis belong to the TALE-class of homeodomain-containing transcription factors and act as generic cofactors of Hox proteins for AP axis patterning in Bilateria. Recent data indicate that Hox proteins acquired the ability to interact with their TALE partners in the last common ancestor of Bilateria and Cnidaria. These interactions relied initially on a short peptide motif called hexapeptide (HX), which is present in Hox and non-Hox protein families. Remarkably, Hox proteins can also recruit the TALE cofactors by using specific PBC Interaction Motifs (SPIMs). We describe how a functional Hox/TALE patterning system emerged in eumetazoans through the acquisition of SPIMs. We anticipate that interaction flexibility could be found in other patterning systems, being at the heart of the astonishing morphological diversity observed in the animal kingdom.

  15. Control of plant architecture by distinctive TALE homeobox gene interactions

    NARCIS (Netherlands)

    Bao, D.|info:eu-repo/dai/nl/304838063

    2009-01-01

    In eukaryotes, transcription factor (TF)-based network is a widely used mechanism to regulate fundamental developmental processes. Both animals and plants utilize three-amino-acid-loop-extension (TALE) homeodomain (HD) transcription factors to subdivide their body plan. In animals, MEIS/PBC TF

  16. Telling Different Tales: Possible Childhoods in Children's Literature

    Science.gov (United States)

    Sreenivas, Deepa

    2011-01-01

    This article draws on the insights/questions that emerged while putting together a set of stories for children published in a series named "Different Tales." These stories, set in Dalit and other minority communities, problematize the normative grids through which we view "childhood" as they depict the complex ways in which…

  17. Effects of Heat of Vaporization and Octane Sensitivity on Knock-Limited Spark Ignition Engine Performance

    Energy Technology Data Exchange (ETDEWEB)

    Ratcliff, Matthew A [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Burton, Jonathan L [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Sindler, Petr [National Renewable Energy Laboratory (NREL), Golden, CO (United States); McCormick, Robert L [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Christensen, Earl D [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Fouts, Lisa A [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2018-04-03

    Knock-limited loads for a set of surrogate gasolines all having nominal 100 research octane number (RON), approximately 11 octane sensitivity (S), and a heat of vaporization (HOV) range of 390 to 595 kJ/kg at 25 degrees C were investigated. A single-cylinder spark-ignition engine derived from a General Motors Ecotec direct injection (DI) engine was used to perform load sweeps at a fixed intake air temperature (IAT) of 50 degrees C, as well as knock-limited load measurements across a range of IATs up to 90 degrees C. Both DI and pre-vaporized fuel (supplied by a fuel injector mounted far upstream of the intake valves and heated intake runner walls) experiments were performed to separate the chemical and thermal effects of the fuels' knock resistance. The DI load sweeps at 50 degrees C intake air temperature showed no effect of HOV on the knock-limited performance. The data suggest that HOV acts as a thermal contributor to S under the conditions studied. Measurement of knock-limited loads from the IAT sweeps for DI at late combustion phasing showed that a 40 vol% ethanol (E40) blend provided additional knock resistance at the highest temperatures, compared to a 20 vol% ethanol blend and hydrocarbon fuel with similar RON and S. Using the pre-vaporized fuel system, all the high S fuels produced nearly identical knock-limited loads at each temperature across the range of IATs studied. For these fuels RON ranged from 99.2 to 101.1 and S ranged from 9.4 to 12.2, with E40 having the lowest RON and highest S. The higher knock-limited loads for E40 at the highest IATs examined were consistent with the slightly higher S for this fuel, and the lower engine operating condition K values arising from use of this fuel. The study highlights how fuel HOV can affect the temperature at intake valve closing, and consequently the pressure-temperature history of the end gas leading to more negative values of K, thereby enhancing the effect of S on knock resistance.

  18. RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency.

    Science.gov (United States)

    Song, Jun; Yang, Dongshan; Xu, Jie; Zhu, Tianqing; Chen, Y Eugene; Zhang, Jifeng

    2016-01-28

    Zinc-finger nuclease, transcription activator-like effector nuclease and CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 (CRISPR-associated protein 9) are becoming major tools for genome editing. Importantly, knock-in in several non-rodent species has been finally achieved thanks to these customizable nucleases; yet the rates remain to be further improved. We hypothesize that inhibiting non-homologous end joining (NHEJ) or enhancing homology-directed repair (HDR) will improve the nuclease-mediated knock-in efficiency. Here we show that the in vitro application of an HDR enhancer, RS-1, increases the knock-in efficiency by two- to five-fold at different loci, whereas NHEJ inhibitor SCR7 has minimal effects. We then apply RS-1 for animal production and have achieved multifold improvement on the knock-in rates as well. Our work presents tools to nuclease-mediated knock-in animal production, and sheds light on improving gene-targeting efficiencies on pluripotent stem cells.

  19. Closed loop statistical performance analysis of N-K knock controllers

    Science.gov (United States)

    Peyton Jones, James C.; Shayestehmanesh, Saeed; Frey, Jesse

    2017-09-01

    The closed loop performance of engine knock controllers cannot be rigorously assessed from single experiments or simulations because knock behaves as a random process and therefore the response belongs to a random distribution also. In this work a new method is proposed for computing the distributions and expected values of the closed loop response, both in steady state and in response to disturbances. The method takes as its input the control law, and the knock propensity characteristic of the engine which is mapped from open loop steady state tests. The method is applicable to the 'n-k' class of knock controllers in which the control action is a function only of the number of cycles n since the last control move, and the number k of knock events that have occurred in this time. A Cumulative Summation (CumSum) based controller falls within this category, and the method is used to investigate the performance of the controller in a deeper and more rigorous way than has previously been possible. The results are validated using onerous Monte Carlo simulations, which confirm both the validity of the method and its high computational efficiency.

  20. RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency

    Science.gov (United States)

    Song, Jun; Yang, Dongshan; Xu, Jie; Zhu, Tianqing; Chen, Y. Eugene; Zhang, Jifeng

    2016-01-01

    Zinc-finger nuclease, transcription activator-like effector nuclease and CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 (CRISPR-associated protein 9) are becoming major tools for genome editing. Importantly, knock-in in several non-rodent species has been finally achieved thanks to these customizable nucleases; yet the rates remain to be further improved. We hypothesize that inhibiting non-homologous end joining (NHEJ) or enhancing homology-directed repair (HDR) will improve the nuclease-mediated knock-in efficiency. Here we show that the in vitro application of an HDR enhancer, RS-1, increases the knock-in efficiency by two- to five-fold at different loci, whereas NHEJ inhibitor SCR7 has minimal effects. We then apply RS-1 for animal production and have achieved multifold improvement on the knock-in rates as well. Our work presents tools to nuclease-mediated knock-in animal production, and sheds light on improving gene-targeting efficiencies on pluripotent stem cells. PMID:26817820

  1. Dynamic knock detection and quantification in a spark ignition engine by means of a pressure based method

    International Nuclear Information System (INIS)

    Galloni, Enzo

    2012-01-01

    Highlights: ► Experimental data have been analyzed by a pressure based method. ► Knock intensity level depends on a threshold varying with the engine operating point. ► A dynamic method is proposed to overcome the definition of a predetermined threshold. ► The knock intensity of each operating point is quantified by a dimensionless index. ► The knock limited spark advance can be detected by means of this index. - Abstract: In spark ignition engines, knock onset limits the maximum spark advance. An inaccurate identification of this limit penalises the fuel conversion efficiency. Thus it is very important to define a knock detection method able to assess the knock intensity of an engine operating point. Usually, in engine development, knock event is evaluated by analysing the in-cylinder pressure trace. Data are filtered and processed in order to obtain some indices correlated to the knock intensity, then the calculated value is compared to a predetermined threshold. The calibration of this threshold is complex and difficult; statistical approach should be used, but often empirical values are considered. In this paper a method that dynamically calculates the knock threshold necessary to determine the knock event is proposed. The purpose is to resolve cycle by cycle the knock intensity related to an individual engine cycle without setting a predetermined threshold. The method has been applied to an extensive set of experimental data relative to a gasoline spark-ignition engine. Results are correlated to those obtained considering a traditional method, where a statistical approach has been used to detect knock.

  2. Post-irradiation studies on knock-out and pseudo-recoil releases of fission products from fissioning UO2

    International Nuclear Information System (INIS)

    Yamagishi, S.; Tanifuji, T.

    1976-01-01

    By using post-irradiation techniques, in-pile releases of 133 Xe, sup(85m)Kr, 88 Kr, 87 Kr and 138 Xe from UO 2 fissioning at low temperatures below about 200 0 C are studied: these are analyzed into a time-dependent knock-out and time-independent pseudo-recoil releases. For the latter, a 'self knock-out' mechanism is proposed: when a fission fragment loses thoroughly its energy near the UO 2 surface and stops there, it will knock out the surface substances and accordingly the fragment (i.e. the fission product) will be released. The effective thickness of the layer where the self knock-out occurs is found to be approximately 7A. As for the knock-out release, the following is estimated from its dependence on various factors: the knock-out release of fission products occurs from the surface layer with the effective thickness of approximately 20A: the shape of UO 2 matrix knocked out by one fission fragment passing through the surface is equivalent to a cylinder approximately 32A diameter by approximately 27A thick, (i.e. the knock-out coefficient for UO 2 is approximately 660 uranium atoms per knock-out event). On the basis of the above estimations, the conclusions derived from the past in-pile studies of fission gas releases are evaluated. (Auth.)

  3. Coupled jump rotational dynamics in aqueous nitrate solutions.

    Science.gov (United States)

    Banerjee, Puja; Yashonath, Subramanian; Bagchi, Biman

    2016-12-21

    A nitrate ion (NO 3 - ) with its trigonal planar geometry and charges distributed among nitrogen and oxygen atoms can couple to the extensive hydrogen bond network of water to give rise to unique dynamical characteristics. We carry out detailed atomistic simulations and theoretical analyses to investigate these aspects and report certain interesting findings. We find that the nitrate ions in aqueous potassium nitrate solution exhibit large amplitude rotational jump motions that are coupled to the hydrogen bond rearrangement dynamics of the surrounding water molecules. The jump motion of nitrate ions bears certain similarities to the Laage-Hynes mechanism of rotational jump motions of tagged water molecules in neat liquid water. We perform a detailed atomic-level investigation of hydrogen bond rearrangement dynamics of water in aqueous KNO 3 solution to unearth two distinct mechanisms of hydrogen bond exchange that are instrumental to promote these jump motions of nitrate ions. As observed in an earlier study by Xie et al., in the first mechanism, after breaking a hydrogen bond with nitrate ion, water forms a new hydrogen bond with a water molecule, whereas the second mechanism involves just a switching of hydrogen bond between the two oxygen atoms of the same nitrate ion (W. J. Xie et al., J. Chem. Phys. 143, 224504 (2015)). The magnitude as well as nature of the reorientational jump of nitrate ion for the two mechanisms is different. In the first mechanism, nitrate ion predominantly undergoes out-of-plane rotation, while in the second mechanism, in-plane reorientation of NO 3 - is favourable. These have been deduced by computing the torque on the nitrate ion during the hydrogen bond switching event. We have defined and computed the time correlation function for coupled reorientational jump of nitrate and water and obtained the associated relaxation time which is also different for the two mechanisms. These results provide insight into the relation between the

  4. Fokker-Planck simulations of knock-on electron runaway avalanche and bursts in tokamaks

    International Nuclear Information System (INIS)

    Chiu, S.C.; Rosenbluth, M.N.; Harvey, R.W.; Chan, V.S.

    1998-01-01

    The avalanche of runaway electrons in an ohmic tokamak plasma triggered by knock-on collisions of traces of energetic electrons with the bulk electrons is simulated by the bounce averaged Fokker-Planck code, CQL3D. It is shown that even when the electric field is small for the production of Dreicer runaways, the knock-on collisions can produce significant runaway electrons in a fraction of a second at typical reactor parameters. The energy spectrum of these knock-on runaways has a characteristic temperature. The growth rate and temperature of the runaway distribution are determined and compared with theory. In simulations of pellet injection into high temperature plasmas, it is shown that a burst of Dreicer runaways may also occur depending on the cooling rate due to the pellet injection. Implications of these phenomena on disruption control in reactor plasmas are discussed. (author)

  5. High-temperature expansion and knock-out properties of moulding sands with water glass

    Directory of Open Access Journals (Sweden)

    Major-Gabryś K.

    2007-01-01

    Full Text Available The article focuses on the topic of improving the knock-out properties of moulding sand with water glass and ester hardener. It is settled that the cause of worse knock-out properties of moulding sand can be brought by their thermal expansion in increased temperatures. There is a presentation of the influence of different additives, containing Al2O3, on moulding sands’ expansion in increased temperatures. Within the frames of research, there was an elaboration of the influence of authors own additive- Glassex, on the expansion phenomenon of moulding sands with water glass and ester hardener. It is concluded, that the new additive stops the expansion of moulding sands and as well it improves their knock-out properties.

  6. A model of knock-out of oxygen by charged particle irradiation of Bi-2212

    International Nuclear Information System (INIS)

    Bandyopadhyay, S.K.; Sen, Pintu; Barat, P.; Mukherjee, P.; Das, S.K.; Ghosh, B.

    1996-01-01

    A model of knock-out of oxygen by charged particle (α and proton) irradiation of Bi 2 Sr 2 CaCu 2 O 8+x (Bi-2212) is proposed on the basis of Monte Carlo TRIM calculations. In Bi-2212, the loosely bound excess oxygen is vulnerable to be displaced by particle irradiation. Binding energy and hence, displacement energy of this loosely bound excess oxygen is less compared to that of stoichiometric lattice bound oxygen and other atoms. The displaced or knocked out oxygen goes to pores or intergranular region and generates large pressure inside the sample. Because of porosity of the material, this displaced oxygen diffuses out and there is a net reduction of oxygen content of the sample. The irradiation induced oxygen knock-out is dominant in the bulk where nonionizing energy loss is maximum. (author). 29 refs., 1 fig., 3 tabs

  7. Hyperactivity of newborn Pten knock-out neurons results from increased excitatory synaptic drive.

    Science.gov (United States)

    Williams, Michael R; DeSpenza, Tyrone; Li, Meijie; Gulledge, Allan T; Luikart, Bryan W

    2015-01-21

    Developing neurons must regulate morphology, intrinsic excitability, and synaptogenesis to form neural circuits. When these processes go awry, disorders, including autism spectrum disorder (ASD) or epilepsy, may result. The phosphatase Pten is mutated in some patients having ASD and seizures, suggesting that its mutation disrupts neurological function in part through increasing neuronal activity. Supporting this idea, neuronal knock-out of Pten in mice can cause macrocephaly, behavioral changes similar to ASD, and seizures. However, the mechanisms through which excitability is enhanced following Pten depletion are unclear. Previous studies have separately shown that Pten-depleted neurons can drive seizures, receive elevated excitatory synaptic input, and have abnormal dendrites. We therefore tested the hypothesis that developing Pten-depleted neurons are hyperactive due to increased excitatory synaptogenesis using electrophysiology, calcium imaging, morphological analyses, and modeling. This was accomplished by coinjecting retroviruses to either "birthdate" or birthdate and knock-out Pten in granule neurons of the murine neonatal dentate gyrus. We found that Pten knock-out neurons, despite a rapid onset of hypertrophy, were more active in vivo. Pten knock-out neurons fired at more hyperpolarized membrane potentials, displayed greater peak spike rates, and were more sensitive to depolarizing synaptic input. The increased sensitivity of Pten knock-out neurons was due, in part, to a higher density of synapses located more proximal to the soma. We determined that increased synaptic drive was sufficient to drive hypertrophic Pten knock-out neurons beyond their altered action potential threshold. Thus, our work contributes a developmental mechanism for the increased activity of Pten-depleted neurons. Copyright © 2015 the authors 0270-6474/15/350943-17$15.00/0.

  8. Knock knee and the gait of six-year-old children.

    Science.gov (United States)

    Pretkiewicz-Abacjew, E

    2003-06-01

    Knock knee (genu valgum) interferes with the locomotive and supporting function of the lower limb. In static conditions the load-bearing axis of the valgus limb is displaced laterally in relation to the middle of the joint, causing the knee joint, the ankle joint, and the foot as a whole to be weighted in the wrong way. The purpose of this work is to examine the influence of knock knee on gait kinematics. The gait of twenty-two 6-year-old children of both sexes in whom knock knee had been medically diagnosed was compared with the gait of 33 children of the same age whose knee joints conformed to the norm in formation and position. Gait was recorded separately for the sagittal and the frontal planes, using a video-computer system. The results of the examination indicated statistically significant differences in the gait of the two groups of children. These differences related mainly to the time features of gait and to data on the angles in the knee and ankle joints. Although the results obtained for other features of gait did not reveal statistical differences, these did indicate that the children with knock knee walked more slowly and with a lower cadence. The results indicate that knock knee in 6-year-old children has an adverse impact on the mechanics of the lower limb joints in gait and causes a deterioration in gait quality. Thus knock knee in children should not be treated merely as a superficial defect but should be subject to therapy and, more importantly, taken into account when introducing children to early sports training.

  9. Sub-Poissonian statistics of quantum jumps in single molecule or atomic ion

    International Nuclear Information System (INIS)

    Osad'ko, I.S.; Gus'kov, D.N.

    2007-01-01

    A theory for statistics of quantum jumps in single molecule or ion driven by continues wave laser field is developed. These quantum jumps can relate to nonradiative singlet-triplet transitions in a molecule or to on → off jumps in a single ion with shelving processes. Distribution function w N (T) of quantum jumps in time interval T is found. Computer simulation of quantum jumps is realized. Statistical treatment of simulated jumps reveals sub-Poissonian statistics of quantum jumps. The theoretical distribution function w N (T) fits well the distribution of jumps found from simulated data. Experimental data on quantum jumps found in experiments with single Hg + ion are described by the function w N (T) well

  10. THE EFFECTS OF SINGLE VERSUS REPEATED PLYOMETRICS ON LANDING BIOMECHANICS AND JUMPING PERFORMANCE IN MEN

    Directory of Open Access Journals (Sweden)

    H. Makaruk

    2014-07-01

    Full Text Available The aim of this study was to examine the chronic effects of single and repeated jumps training on vertical landing force (VGRF and jump height in untrained men. The VGRF and jump height were compared after a six-week plyometric training programme containing single and repeated jumps, together with two additional parameters: landing time (LT and range of the knee flexion during landing (KF. Thirty-six untrained physical education students with a plyometric training background were randomly assigned to a single jump group (SJG, n =12, repeated jumps group (RJG, n =12, and control group (CON, n =12. The SJG performed only single jumps, the RJG executed repeated (consecutive jumps, whereas the CON did not perform any exercises at all. A countermovement jump (CMJ, repeated countermovement jumps (RCMJ, and a drop jump (DJ were tested before and after the training. Only the RJG showed a significantly reduced VGRF (p<0.05 in all tests. Both plyometric groups significantly improved (p<0.05 their jump height in all tests. The LT was significantly greater in the RJG, compared to the SJG, in all tests. The KF was also significantly (p<0.05 greater in the RJG than in the SJG for CMJ and RCMJ. The results suggest that repeated jumps are beneficial for simultaneous landing force reduction and jumping performance enhancement.

  11. A data-driven wavelet-based approach for generating jumping loads

    Science.gov (United States)

    Chen, Jun; Li, Guo; Racic, Vitomir

    2018-06-01

    This paper suggests an approach to generate human jumping loads using wavelet transform and a database of individual jumping force records. A total of 970 individual jumping force records of various frequencies were first collected by three experiments from 147 test subjects. For each record, every jumping pulse was extracted and decomposed into seven levels by wavelet transform. All the decomposition coefficients were stored in an information database. Probability distributions of jumping cycle period, contact ratio and energy of the jumping pulse were statistically analyzed. Inspired by the theory of DNA recombination, an approach was developed by interchanging the wavelet coefficients between different jumping pulses. To generate a jumping force time history with N pulses, wavelet coefficients were first selected randomly from the database at each level. They were then used to reconstruct N pulses by the inverse wavelet transform. Jumping cycle periods and contract ratios were then generated randomly based on their probabilistic functions. These parameters were assigned to each of the N pulses which were in turn scaled by the amplitude factors βi to account for energy relationship between successive pulses. The final jumping force time history was obtained by linking all the N cycles end to end. This simulation approach can preserve the non-stationary features of the jumping load force in time-frequency domain. Application indicates that this approach can be used to generate jumping force time history due to single people jumping and also can be extended further to stochastic jumping loads due to groups and crowds.

  12. Development of a one-step gene knock-out and knock-in method for metabolic engineering of Aureobasidium pullulans.

    Science.gov (United States)

    Guo, Jian; Wang, Yuanhua; Li, Baozhong; Huang, Siyao; Chen, Yefu; Guo, Xuewu; Xiao, Dongguang

    2017-06-10

    Aureobasidium pullulans is an increasingly attractive host for bio-production of pullulan, heavy oil, polymalic acid, and a large spectrum of extracellular enzymes. To date, genetic manipulation of A. pullulans mainly relies on time-consuming conventional restriction enzyme digestion and ligation methods. In this study, we present a one-step homologous recombination-based method for rapid genetic manipulation in A. pullulans. Overlaps measuring >40bp length and 10μg DNA segments for homologous recombination provided maximum benefits to transformation of A. pullulans. This optimized method was successfully applied to PKSIII gene (encodes polyketide synthase) knock-out and gltP gene (encodes glycolipid transfer protein) knock-in. After disruption of PKSIII gene, secretion of melanin decreased slightly. The melanin purified from disruptant showed lower reducing capacity compared with that of the parent strain, leading to a decrease in exopolysaccharide production. Knock-in of gltP gene resulted in at least 4.68-fold increase in heavy oil production depending on the carbon source used, indicating that gltP can regulate heavy oil synthesis in A. pullulans. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. On the interpretation of (e,e'p) knock-out reaction

    International Nuclear Information System (INIS)

    Dieperink, A.E.L.

    The basic physics in (e,e'p) knock-out reactions is illustrated assuming that the knocked-out proton can be treated as a plane wave (PWIA). Corrections for distortion and absorption of the outgoing proton can, in principle, be calculated to a good approximation with an optical potential. The spectral function is characterized in terms of its energy moments, the lowest of which can be incorporated in an independent particle shell model (IPSM): occupatiomn probability (zeroth moment) and the mean removal energy (centroid energy). Deviations from IPSM are discussed: binding energy sum rule, A=3 nuclei, 6 Li, and fragmentation of single-particle strength

  14. Knock-on type exchange and the density dependence of an effective interaction

    International Nuclear Information System (INIS)

    Jeukenne, J.P.; Mahaux, C.

    1981-01-01

    We investigate the origin of the density-dependence of the strength of an effective interaction previously derived from a Brueckner-Hartree-Fock calculation of the optical-model potential in nuclear matter. From the analysis of a model based on the Hartree-Fock approximation and on a Yukawa interaction with a Majorana exchange component, we study to what extent this dependence derives from the momentum-dependence of the exchange contribution of the knock-on type. The model is also used to discuss zero-range pseudopotential methods for including this knock-on contribution. (orig.)

  15. CONNECTION OF FUNCTIONAL ABILITIES WITH JUMPING AND THROWING ATHLETIC DISCIPLINES

    Directory of Open Access Journals (Sweden)

    Igor Stanojević

    2014-06-01

    Full Text Available The aim of this study was to determine the connection between functional abilities with results of jumping and throwing athletic disciplines with athletes. The sample was taken from a population of elementary school students from Prokuplje region, 13 and 14 old, included in regular physical education classes. The sample consisted of 200 male athletes involved in the training process in sports clubs at least three times a week in addition to physical education classes. For assessment of functional abilities six functional tests were used: resting heart rate, Cooper test, heart rate in the first minute after Cooper test, heart rate in the second minute after Cooper test, systolic arterial blood pressure, diastolic arterial blood pressure. For assessment of jumping and throwing athletic disciplines four tests were used: long jump, high jump, shot put and javelin. Data analysis was performed with canonical correlation and regression analysis. The results showed a statistically significant correlation between functional abilities with all of tests in jumping and throwing athletic disciplines.

  16. Mechanical parameters and flight phase characteristics in aquatic plyometric jumping.

    Science.gov (United States)

    Louder, Talin J; Searle, Cade J; Bressel, Eadric

    2016-09-01

    Plyometric jumping is a commonly prescribed method of training focused on the development of reactive strength and high-velocity concentric power. Literature suggests that aquatic plyometric training may be a low-impact, effective supplement to land-based training. The purpose of the present study was to quantify acute, biomechanical characteristics of the take-off and flight phase for plyometric movements performed in the water. Kinetic force platform data from 12 young, male adults were collected for counter-movement jumps performed on land and in water at two different immersion depths. The specificity of jumps between environmental conditions was assessed using kinetic measures, temporal characteristics, and an assessment of the statistical relationship between take-off velocity and time in the air. Greater peak mechanical power was observed for jumps performed in the water, and was influenced by immersion depth. Additionally, the data suggest that, in the water, the statistical relationship between take-off velocity and time in air is quadratic. Results highlight the potential application of aquatic plyometric training as a cross-training tool for improving mechanical power and suggest that water immersion depth and fluid drag play key roles in the specificity of the take-off phase for jumping movements performed in the water.

  17. Anthropic prediction for a large multi-jump landscape

    International Nuclear Information System (INIS)

    Schwartz-Perlov, Delia

    2008-01-01

    The assumption of a flat prior distribution plays a critical role in the anthropic prediction of the cosmological constant. In a previous paper we analytically calculated the distribution for the cosmological constant, including the prior and anthropic selection effects, in a large toy 'single-jump' landscape model. We showed that it is possible for the fractal prior distribution that we found to behave as an effectively flat distribution in a wide class of landscapes, but only if the single-jump size is large enough. We extend this work here by investigating a large (N∼10 500 ) toy 'multi-jump' landscape model. The jump sizes range over three orders of magnitude and an overall free parameter c determines the absolute size of the jumps. We will show that for 'large' c the distribution of probabilities of vacua in the anthropic range is effectively flat, and thus the successful anthropic prediction is validated. However, we argue that for small c, the distribution may not be smooth

  18. Self-jumping Mechanism of Melting Frost on Superhydrophobic Surfaces.

    Science.gov (United States)

    Liu, Xiaolin; Chen, Huawei; Zhao, Zehui; Wang, Yamei; Liu, Hong; Zhang, Deyuan

    2017-11-07

    Frost accretion on surfaces may cause severe problems and the high-efficiency defrosting methods are still urgently needed in many application fields like heat transfer, optical and electric power system, etc. In this study, a nano-needle superhydrophobic surface is prepared and the frosting/defrosting experiments are conducted on it. Three steps are found in the defrosting process: melting frost shrinking and splitting, instantaneous self-triggered deforming followed by deformation-induced movements (namely, in-situ shaking, rotating, rolling, and self-jumping). The self-jumping performance of the melting frost is extremely fascinating and worth studying due to its capability of evidently shortening the defrosting process and reducing (even avoiding) residual droplets after defrosting. The study on the melting frost self-jumping phenomena demonstrates that the kinetic energy transformed from instantaneous superficial area change in self-triggered deforming step is the intrinsic reason for various melting frost self-propelled movements, and when the transformed energy reaches a certain amount, the self-jumping phenomena occur. And some facilitating conditions for melting frost self-jumping phenomena are also discussed. This work will provide an efficient way for defrosting or an inspiration for further research on defrosting.

  19. Bayesian inference for Markov jump processes with informative observations.

    Science.gov (United States)

    Golightly, Andrew; Wilkinson, Darren J

    2015-04-01

    In this paper we consider the problem of parameter inference for Markov jump process (MJP) representations of stochastic kinetic models. Since transition probabilities are intractable for most processes of interest yet forward simulation is straightforward, Bayesian inference typically proceeds through computationally intensive methods such as (particle) MCMC. Such methods ostensibly require the ability to simulate trajectories from the conditioned jump process. When observations are highly informative, use of the forward simulator is likely to be inefficient and may even preclude an exact (simulation based) analysis. We therefore propose three methods for improving the efficiency of simulating conditioned jump processes. A conditioned hazard is derived based on an approximation to the jump process, and used to generate end-point conditioned trajectories for use inside an importance sampling algorithm. We also adapt a recently proposed sequential Monte Carlo scheme to our problem. Essentially, trajectories are reweighted at a set of intermediate time points, with more weight assigned to trajectories that are consistent with the next observation. We consider two implementations of this approach, based on two continuous approximations of the MJP. We compare these constructs for a simple tractable jump process before using them to perform inference for a Lotka-Volterra system. The best performing construct is used to infer the parameters governing a simple model of motility regulation in Bacillus subtilis.

  20. The kinematics of swimming and relocation jumps in copepod nauplii

    DEFF Research Database (Denmark)

    Borg, Marc Andersen; Bruno, Eleonora; Kiørboe, Thomas

    2012-01-01

    Copepod nauplii move in a world dominated by viscosity. Their swimming-by-jumping propulsion mode, with alternating power and recovery strokes of three pairs of cephalic appendages, is fundamentally different from the way other microplankters move. Protozoans move using cilia or flagella, and cop......Copepod nauplii move in a world dominated by viscosity. Their swimming-by-jumping propulsion mode, with alternating power and recovery strokes of three pairs of cephalic appendages, is fundamentally different from the way other microplankters move. Protozoans move using cilia or flagella...... of pelagic copepods: Temora longicornis, Oithona davisae and Acartia tonsa. The kinematics of jumping is similar between the three species. Jumps result in a very erratic translation with no phase of passive coasting and the nauplii move backwards during recovery strokes. This is due to poorly synchronized...... recovery strokes and a low beat frequency relative to the coasting time scale. For the same reason, the propulsion efficiency of the nauplii is low. Given the universality of the nauplius body plan, it is surprising that they seem to be inefficient when jumping, which is different from the very efficient...

  1. Jump point detection for real estate investment success

    Science.gov (United States)

    Hui, Eddie C. M.; Yu, Carisa K. W.; Ip, Wai-Cheung

    2010-03-01

    In the literature, studies on real estate market were mainly concentrating on the relation between property price and some key factors. The trend of the real estate market is a major concern. It is believed that changes in trend are signified by some jump points in the property price series. Identifying such jump points reveals important findings that enable policy-makers to look forward. However, not all jump points are observable from the plot of the series. This paper looks into the trend and introduces a new approach to the framework for real estate investment success. The main purpose of this paper is to detect jump points in the time series of some housing price indices and stock price index in Hong Kong by applying the wavelet analysis. The detected jump points reflect to some significant political issues and economic collapse. Moreover, the relations among properties of different classes and between stocks and properties are examined. It can be shown from the empirical result that a lead-lag effect happened between the prices of large-size property and those of small/medium-size property. However, there is no apparent relation or consistent lead in terms of change point measure between property price and stock price. This may be due to the fact that globalization effect has more impact on the stock price than the property price.

  2. Vertical jumping tests in volleyball: reliability, validity, and playing-position specifics.

    Science.gov (United States)

    Sattler, Tine; Sekulic, Damir; Hadzic, Vedran; Uljevic, Ognjen; Dervisevic, Edvin

    2012-06-01

    Vertical jumping is known to be important in volleyball, and jumping performance tests are frequently studied for their reliability and validity. However, most studies concerning jumping in volleyball have dealt with standard rather than sport-specific jumping procedures and tests. The aims of this study, therefore, were (a) to determine the reliability and factorial validity of 2 volleyball-specific jumping tests, the block jump (BJ) test and the attack jump (AJ) test, relative to 2 frequently used and systematically validated jumping tests, the countermovement jump test and the squat jump test and (b) to establish volleyball position-specific differences in the jumping tests and simple anthropometric indices (body height [BH], body weight, and body mass index [BMI]). The BJ was performed from a defensive volleyball position, with the hands positioned in front of the chest. During an AJ, the players used a 2- to 3-step approach and performed a drop jump with an arm swing followed by a quick vertical jump. A total of 95 high-level volleyball players (all men) participated in this study. The reliability of the jumping tests ranged from 0.97 to 0.99 for Cronbach's alpha coefficients, from 0.93 to 0.97 for interitem correlation coefficients and from 2.1 to 2.8 for coefficients of variation. The highest reliability was found for the specific jumping tests. The factor analysis extracted one significant component, and all of the tests were highly intercorrelated. The analysis of variance with post hoc analysis showed significant differences between 5 playing positions in some of the jumping tests. In general, receivers had a greater jumping capacity, followed by libero players. The differences in jumping capacities should be emphasized vis-a-vis differences in the anthropometric measures of players, where middle hitters had higher BH and body weight, followed by opposite hitters and receivers, with no differences in the BMI between positions.

  3. Relative Intensity Influences the Degree of Correspondence of Jump Squats and Push Jerks to Countermovement Jumps.

    Science.gov (United States)

    Cushion, Emily J; Goodwin, Jon E; Cleather, Daniel J

    2016-05-01

    The aim of this study was to determine the mechanical similarity between push jerk (PJ) and jump squat (JS) to countermovement jump (CMJ) and further understand the effect increasing external load may have on this relationship. Eight physically trained men (age 22 ± 3; height 176 ± 7 kg; weight 83 ± 8 kg) performed an unloaded CMJ followed by JS under a range of loads (10, 25, 35, and 50% 1RM back squat) and PJ (30, 50, 65, and 75% 1RM push jerk). A portable force platform and high-speed camera both collecting at 250 Hz were used to establish joint moments and impulse during the propulsive phase of the movements. A standard inverse dynamics model was used to determine joint moment and impulse at the hip, knee, and ankle. Significant correlations (p ≤ 0.05) were shown between CMJ knee joint moment and JS knee joint moment at 25% load and PJ knee joint moment at 30 and 50% load. Significant correlations were also observed between CMJ knee joint impulse and JS knee joint impulse at 10% load and PJ knee joint moment at 30 and 65% load. Significant correlation was also observed between CMJ hip joint impulse and PJ hip joint impulse at 30% load. No significant joint × load interaction was shown as load increased for either PJ or JS. Results from the study suggest partial correspondence between PJ and JS to CMJ, where a greater mechanical similarity was observed between the PJ and CMJ. This interaction is load and joint dependent where lower relative loads showed greatest mechanical similarity. Therefore using lower relative loads when programming may provide a greater transfer of training effect.

  4. Dissipation-Free Jumps for the Magnetosonic Branch of Cold Plasma Motion

    International Nuclear Information System (INIS)

    Bakholdin, I.B.

    2000-01-01

    Dissipation-free jumps are studied in a hydrodynamic model of a cold plasma moving at about magnetosonic speed. The jumps described by the generalized Korteweg-de Vries equation, which possesses similar nonlinear and dispersion properties, are considered. In particular, jumps with emission and solitonlike jumps are considered. The assumption that our model possesses jumps of the same type as those for the generalized Korteweg-de Vries equation is justified by numerically investigating the problem of the decay of an initial discontinuity in a cold plasma. An analytic method is described that makes it possible to predict the structure of such jumps in the general case

  5. Dissipative - free jumps for the magnetoacoustic branch of cold plasma motions

    International Nuclear Information System (INIS)

    Bakholdin, I.B.

    2000-01-01

    Dissipative-free jumps were studied in hydrodynamic model of cold plasma moving with the rate close to magnetoacoustic one. The jumps for the generalized Korteweg-de Vries equation with similar nonlinear and dispersion properties were studied. Among them there were jumps with emission and solution type jumps. Furthermore, the numerical investigation into the initial break decomposition in cold plasma confirmed the validity of assumption that in the given type of jumps as in case of the generalized Korteweg-de Vries equation. Paper describes the analytical method enabling to forecast the structure nature of such jumps in the general case [ru

  6. Nordic ski jumping injuries. A survey of active American jumpers.

    Science.gov (United States)

    Wright, J R; McIntyre, L; Rand, J J; Hixson, E G

    1991-01-01

    Little data are available in the medical literature on nordic ski jumping injuries. Injury questionnaires were sent to all active American ski jumpers registered either with the United States Ski Association or with a jumping club registered with the United States Ski Association. One hundred thirty-three of 286 (46.5%) injury questionnaires were returned. Eighty-one of the 133 respondents (60.9%) had been injured sufficiently to require examination by a physician at least once during their jumping careers. This report describes the types and frequencies of injuries sustained by this group of nordic ski jumpers as well as provides demographic data about American ski jumpers. The risk of injury per 100 participant years was 9.4, a rate less than that reported for most high school or college intermural sports.

  7. Dynamical Jumps in a Shape Memory Alloy Oscillator

    Directory of Open Access Journals (Sweden)

    H. S. Oliveira

    2014-01-01

    Full Text Available The dynamical response of systems with shape memory alloy (SMA elements presents a rich behavior due to their intrinsic nonlinear characteristic. SMA’s nonlinear response is associated with both adaptive dissipation related to hysteretic behavior and huge changes in properties caused by phase transformations. These characteristics are attracting much technological interest in several scientific and engineering fields, varying from medical to aerospace applications. An important characteristic associated with dynamical response of SMA system is the jump phenomenon. Dynamical jumps result in abrupt changes in system behavior and its analysis is essential for a proper design of SMA systems. This paper discusses the nonlinear dynamics of a one degree of freedom SMA oscillator presenting pseudoelastic behavior and dynamical jumps. Numerical simulations show different aspects of this kind of behavior, illustrating its importance for a proper understanding of nonlinear dynamics of SMA systems.

  8. Hydraulic jumps in a partially filled rotating cylinder

    International Nuclear Information System (INIS)

    Lundgren, T.S.; Berman, A.S.

    1979-06-01

    A nonlinear analysis is made of the fluid dynamics of a thin film of liquid completely spun up along the cylindrical wall of a rotating cylinder. The analysis allows for the possibility of hydraulic jumps in the liquid film. Conditions are simulated under which jumps can occur. Under the assumption that synchronous runouts are small relative to the film thickness, a sample calculation of jump position and extent for various operating frequencies is presented. Comparison with experimental observations indicate good qualitative agreement between the analysis and the experiment. Under the additional restriction of constant film thickness and a simple lumped-parameter dynamic model for the rotor and its supports, an analysis is also provided which predicts the amplitude and frequency of the asynchronous runout as a function of operating frequency. A numerical example of the results of such a calculation is provided. 6 figures

  9. Aerodynamic Jump: A Short Range View for Long Rod Projectiles

    Directory of Open Access Journals (Sweden)

    Mark Bundy

    2001-01-01

    Full Text Available It is shown that aerodynamic jump for a nonspinning kinetic energy penetrator is not – as conventional definitions may infer – a discontinuous change in the direction of motion at the origin of free flight, nor is it the converse, a cumulative redirection over a domain of infinite extent. Rather, with the aid of an alternative kinematical definition, it is shown that aerodynamic jump for such a projectile is a localized redirection of the center-of-gravity motion, caused by the force of lift due to yaw over the relatively short region from entry into free flight until the yaw reaches its first maximum. A rigorous proof of this statement is provided, but the primary objective of this paper is to provide answers to the questions: what is aerodynamic jump, what does it mean, and what aspects of the flight trajectory does it refer to, or account for.

  10. Adaptive jump barrier height in Monte Carlo configuration kinetics.

    Energy Technology Data Exchange (ETDEWEB)

    Leitner, Martin; Pfeiler, Wolfgang; Pueschl, Wolfgang [Dynamics of Condensed Systems, Faculty of Physics, University of Vienna, Strudlhofgasse 4, A-1090 Wien (Austria); Vogtenhuber, Doris [Computational Materials Science, Faculty of Physics, University of Vienna, Sensengasse 8, A-1090 Wien (Austria)

    2008-07-01

    In usual MC simulations of configuration kinetics atom jump probabilities are calculated from energies of the initial and/or final bound states of the moving atom, leaving aside the exact energy of the intermediate saddle point state. This energy may however be critically influenced by the local atomic environment. We propose a strategy to explicitly take account of this influence. The basis is ab initio calculation of representative jump paths in the framework of the nudged elastic band method. From these results, an influence function is derived which modifies the energy of the saddle point and therefore the effective jump barrier height as calculated from the initial and final states according to a cluster expansion scheme. The overall effect is demonstrated on the NiAl system.

  11. Device for investigation of magnetic flux jumps in ribbon superconductors

    International Nuclear Information System (INIS)

    Andrianov, A.V.; Bashkirov, Yu.A.; Kremlev, M.G.

    1986-01-01

    A device for simulation of magnetic flux jumps in superconductors of conducting magnet sandwich-type windings super-applyed of a ribbon conductor is described. A superconducting magnet with a measuring cassetter are the main elements of the device. An external magnetic field is generated by a two-sectional superconducting magnet permitting to simulate the shape of the magnetic field characteristic for sandwich-type windings. Maximum radial component of the magnetic field is 2 T. Jumps of the magnetic flux are recorded by induction transducers and the magnetic field-by Hall trasducer. The effect of coating of standard metal on magnetic flux jumps in Nb 3 Sn base superconducting ribbon is considered

  12. AGS tune jump power supply design and test

    International Nuclear Information System (INIS)

    Mi, J.; Glenn, J.W.; Huang, H.; Marneris, I.; Rosas, P.; Sandberg, J.; Tan, Y.; Zhang, W.

    2011-01-01

    A horizontal tune jump system has been installed to overcome the horizontal intrinsic spin resonances, which requires jumping the horizontal tune 0.04 units 82 times, 41 up and 41 down. Two quadruple magnets have been installed in AGS ring to perform this. The pulsed magnet current ranges from about 140A near injection to about 1400A later. The current pulse rise and fall time are around 100uS and flat tops time is around 4mS. These quadruples have separated supplies. This tune jump pulse power supply employees all semiconductor parts as well as the main switches. During dummy load and magnet testing, the test results showed that the power supply could meet the specification. This article will describe some details of power supply simulation, design and testing. Some test waveforms and pictures are presented in this paper.

  13. Birth-jump processes and application to forest fire spotting.

    Science.gov (United States)

    Hillen, T; Greese, B; Martin, J; de Vries, G

    2015-01-01

    Birth-jump models are designed to describe population models for which growth and spatial spread cannot be decoupled. A birth-jump model is a nonlinear integro-differential equation. We present two different derivations of this equation, one based on a random walk approach and the other based on a two-compartmental reaction-diffusion model. In the case that the redistribution kernels are highly concentrated, we show that the integro-differential equation can be approximated by a reaction-diffusion equation, in which the proliferation rate contributes to both the diffusion term and the reaction term. We completely solve the corresponding critical domain size problem and the minimal wave speed problem. Birth-jump models can be applied in many areas in mathematical biology. We highlight an application of our results in the context of forest fire spread through spotting. We show that spotting increases the invasion speed of a forest fire front.

  14. A simple method for quantifying jump loads in volleyball athletes.

    Science.gov (United States)

    Charlton, Paula C; Kenneally-Dabrowski, Claire; Sheppard, Jeremy; Spratford, Wayne

    2017-03-01

    Evaluate the validity of a commercially available wearable device, the Vert, for measuring vertical displacement and jump count in volleyball athletes. Propose a potential method of quantifying external load during training and match play within this population. Validation study. The ability of the Vert device to measure vertical displacement in male, junior elite volleyball athletes was assessed against reference standard laboratory motion analysis. The ability of the Vert device to count jumps during training and match-play was assessed via comparison with retrospective video analysis to determine precision and recall. A method of quantifying external load, known as the load index (LdIx) algorithm was proposed using the product of the jump count and average kinetic energy. Correlation between two separate Vert devices and three-dimensional trajectory data were good to excellent for all jump types performed (r=0.83-0.97), with a mean bias of between 3.57-4.28cm. When matched against jumps identified through video analysis, the Vert demonstrated excellent precision (0.995-1.000) evidenced by a low number of false positives. The number of false negatives identified with the Vert was higher resulting in lower recall values (0.814-0.930). The Vert is a commercially available tool that has potential for measuring vertical displacement and jump count in elite junior volleyball athletes without the need for time-consuming analysis and bespoke software. Subsequently, allowing the collected data to better quantify load using the proposed algorithm (LdIx). Copyright © 2016 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  15. Thirteen and two fairy tales on the energy turning point

    International Nuclear Information System (INIS)

    Keil, Guenter

    2011-01-01

    Inspired by the choices and changes in the German energy policy, the author proposes controversial texts under the form of tales on the German policy and situation regarding energy. These tales ironically address the German energy model, the uselessness of the seven stopped nuclear power plants, the low cost of the energy turnaround made by the German government, the environmental benefit of renewable energies, the high potential of energy savings, the new means of electricity storage, the electric car as means to store electricity, the low cost of solar energy ('Sun does not send any bill'), the wind energy (the wind turbine fleet in such place can supply so much households), the geothermal energy, the so-called technological leap, the benefit of decentralized energy production, the numerous jobs created by renewable energies, the ecologic electric current, and the search for a final nuclear waste disposal site

  16. Rapid and highly efficient construction of TALE-based transcriptional regulators and nucleases for genome modification

    KAUST Repository

    Li, Lixin

    2012-01-22

    Transcription activator-like effectors (TALEs) can be used as DNA-targeting modules by engineering their repeat domains to dictate user-selected sequence specificity. TALEs have been shown to function as site-specific transcriptional activators in a variety of cell types and organisms. TALE nucleases (TALENs), generated by fusing the FokI cleavage domain to TALE, have been used to create genomic double-strand breaks. The identity of the TALE repeat variable di-residues, their number, and their order dictate the DNA sequence specificity. Because TALE repeats are nearly identical, their assembly by cloning or even by synthesis is challenging and time consuming. Here, we report the development and use of a rapid and straightforward approach for the construction of designer TALE (dTALE) activators and nucleases with user-selected DNA target specificity. Using our plasmid set of 100 repeat modules, researchers can assemble repeat domains for any 14-nucleotide target sequence in one sequential restriction-ligation cloning step and in only 24 h. We generated several custom dTALEs and dTALENs with new target sequence specificities and validated their function by transient expression in tobacco leaves and in vitro DNA cleavage assays, respectively. Moreover, we developed a web tool, called idTALE, to facilitate the design of dTALENs and the identification of their genomic targets and potential off-targets in the genomes of several model species. Our dTALE repeat assembly approach along with the web tool idTALE will expedite genome-engineering applications in a variety of cell types and organisms including plants. © 2012 Springer Science+Business Media B.V.

  17. RUSSIAN NATIONAL TALE IN NURTURING CHILD AS AN ASPECT OF THE FORMATION OF HIS PERSONALITY

    Directory of Open Access Journals (Sweden)

    Nikolay Govorov

    2015-09-01

    Full Text Available The article deals with the problem of children nurturing. Given the provisions of the recommended use of Russian national fairy tales in children nurturing. We consider the role of a fairy tale, as an aspect of the success of educational processes in a child immersed in the atmosphere of a modern cyber information of his being. It rips the need to address the problem of writing the words of imagery of Russian fairy tales.

  18. Rapid and highly efficient construction of TALE-based transcriptional regulators and nucleases for genome modification.

    Science.gov (United States)

    Li, Lixin; Piatek, Marek J; Atef, Ahmed; Piatek, Agnieszka; Wibowo, Anjar; Fang, Xiaoyun; Sabir, J S M; Zhu, Jian-Kang; Mahfouz, Magdy M

    2012-03-01

    Transcription activator-like effectors (TALEs) can be used as DNA-targeting modules by engineering their repeat domains to dictate user-selected sequence specificity. TALEs have been shown to function as site-specific transcriptional activators in a variety of cell types and organisms. TALE nucleases (TALENs), generated by fusing the FokI cleavage domain to TALE, have been used to create genomic double-strand breaks. The identity of the TALE repeat variable di-residues, their number, and their order dictate the DNA sequence specificity. Because TALE repeats are nearly identical, their assembly by cloning or even by synthesis is challenging and time consuming. Here, we report the development and use of a rapid and straightforward approach for the construction of designer TALE (dTALE) activators and nucleases with user-selected DNA target specificity. Using our plasmid set of 100 repeat modules, researchers can assemble repeat domains for any 14-nucleotide target sequence in one sequential restriction-ligation cloning step and in only 24 h. We generated several custom dTALEs and dTALENs with new target sequence specificities and validated their function by transient expression in tobacco leaves and in vitro DNA cleavage assays, respectively. Moreover, we developed a web tool, called idTALE, to facilitate the design of dTALENs and the identification of their genomic targets and potential off-targets in the genomes of several model species. Our dTALE repeat assembly approach along with the web tool idTALE will expedite genome-engineering applications in a variety of cell types and organisms including plants.

  19. Overcoming weak intrinsic depolarizing resonances with energy-jump

    International Nuclear Information System (INIS)

    Huang, H.; Ahrens, L.; Alessi, J.G.

    1997-01-01

    In the recent polarized proton runs in the AGS, a 5% partial snake was used successfully to overcome the imperfection depolarizing resonances. Polarized proton beam was accelerated up to the required RHIC injection energy of 25 GeV. However, significant amount of polarization was lost at 0+ν y , 12+ν y and 36+ν y , which is believed to be partially due to the coupling resonances. To overcome the coupling resonance, an energy-jump was generated by rapidly changing the beam circumference using the powerful AGS rf system. It clearly demonstrates that the novel energy-jump method can successfully overcome coupling resonances and weak intrinsic resonances

  20. Orthogonal Expansions for VIX Options Under Affine Jump Diffusions

    DEFF Research Database (Denmark)

    Barletta, Andrea; Nicolato, Elisa

    2017-01-01

    In this work we derive new closed–form pricing formulas for VIX options in the jump-diffusion SVJJ model proposed by Duffie et al. (2000). Our approach is based on the classic methodology of approximating a density function with an orthogonal expansion of polynomials weighted by a kernel. Orthogo......In this work we derive new closed–form pricing formulas for VIX options in the jump-diffusion SVJJ model proposed by Duffie et al. (2000). Our approach is based on the classic methodology of approximating a density function with an orthogonal expansion of polynomials weighted by a kernel...

  1. Heart rate variability as determinism with jump stochastic parameters.

    Science.gov (United States)

    Zheng, Jiongxuan; Skufca, Joseph D; Bollt, Erik M

    2013-08-01

    We use measured heart rate information (RR intervals) to develop a one-dimensional nonlinear map that describes short term deterministic behavior in the data. Our study suggests that there is a stochastic parameter with persistence which causes the heart rate and rhythm system to wander about a bifurcation point. We propose a modified circle map with a jump process noise term as a model which can qualitatively capture such this behavior of low dimensional transient determinism with occasional (stochastically defined) jumps from one deterministic system to another within a one parameter family of deterministic systems.

  2. Jump Telegraph Processes and Financial Markets with Memory

    Directory of Open Access Journals (Sweden)

    Nikita Ratanov

    2007-01-01

    Full Text Available The paper develops a new class of financial market models. These models are based on generalized telegraph processes with alternating velocities and jumps occurring at switching velocities. The model under consideration is arbitrage-free and complete if the directions of jumps in stock prices are in a certain correspondence with their velocity and with the behaviour of the interest rate. A risk-neutral measure and arbitrage-free formulae for a standard call option are constructed. This model has some features of models with memory, but it is more simple.

  3. Pricing Participating Products under a Generalized Jump-Diffusion Model

    Directory of Open Access Journals (Sweden)

    Tak Kuen Siu

    2008-01-01

    Full Text Available We propose a model for valuing participating life insurance products under a generalized jump-diffusion model with a Markov-switching compensator. It also nests a number of important and popular models in finance, including the classes of jump-diffusion models and Markovian regime-switching models. The Esscher transform is employed to determine an equivalent martingale measure. Simulation experiments are conducted to illustrate the practical implementation of the model and to highlight some features that can be obtained from our model.

  4. A logarithmic interpretation of Edixhoven's jumps for Jacobians

    DEFF Research Database (Denmark)

    Eriksson, Dennis; Halle, Lars Halvard; Nicaise, Johannes

    2015-01-01

    Let A be an abelian variety over a discretely valued field. Edixhoven has defined a filtration on the special fiber of the N\\'eron model of A that measures the behaviour of the N\\'eron model under tame base change. We interpret the jumps in this filtration in terms of lattices of logarithmic...... differential forms in the case where A is the Jacobian of a curve C , and we give a compact explicit formula for the jumps in terms of the combinatorial reduction data of C. ...

  5. A Function of Dream Narratives in Fairy Tale

    OpenAIRE

    Judit Gulyás

    2007-01-01

    In Hungarian variants of some fairy tale types (especially ATU 315,707, 725) the operation of a peculiar dream narrative can be observed: the characters use an embedded dream narrative to communicate information. The agent of knowledge conveys information to a mediating person and in doing so (s)he also governs that when the mediator conveys information to the actual addressee (recipient), the mediator must explain the origin of the conveyed knowledge to the recipient by referring to a fictio...

  6. Validation of an inertial measurement unit for the measurement of jump count and height.

    Science.gov (United States)

    MacDonald, Kerry; Bahr, Roald; Baltich, Jennifer; Whittaker, Jackie L; Meeuwisse, Willem H

    2017-05-01

    To validate the use of an inertial measurement unit (IMU) for the collection of total jump count and assess the validity of an IMU for the measurement of jump height against 3-D motion analysis. Cross sectional validation study. 3D motion-capture laboratory and field based settings. Thirteen elite adolescent volleyball players. Participants performed structured drills, played a 4 set volleyball match and performed twelve counter movement jumps. Jump counts from structured drills and match play were validated against visual count from recorded video. Jump height during the counter movement jumps was validated against concurrent 3-D motion-capture data. The IMU device captured more total jumps (1032) than visual inspection (977) during match play. During structured practice, device jump count sensitivity was strong (96.8%) while specificity was perfect (100%). The IMU underestimated jump height compared to 3D motion-capture with mean differences for maximal and submaximal jumps of 2.5 cm (95%CI: 1.3 to 3.8) and 4.1 cm (3.1-5.1), respectively. The IMU offers a valid measuring tool for jump count. Although the IMU underestimates maximal and submaximal jump height, our findings demonstrate its practical utility for field-based measurement of jump load. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Experimental investigation on the knocking combustion characteristics of n-butanol gasoline blends in a DISI engine

    International Nuclear Information System (INIS)

    Wei, Haiqiao; Feng, Dengquan; Pan, Mingzhang; Pan, JiaYing; Rao, XiaoKang; Gao, Dongzhi

    2016-01-01

    Highlights: • N-butanol shows better knock resistance characterized by improved KLST. • Bu20 blend fuel slightly degrades the knock resistance compared with gasoline. • Knock oscillation frequency depends on combustion chamber resonance modes. • Probability distribution is applied to evaluate variation of knock intensity. - Abstract: n-Butanol is a very competitive alternative biofuel for spark ignition (SI) engines given its many advantages. Current researches are mainly concentrated on the overall combustion and emissions performance concerning the feasibility of n-butanol gasoline blends in SI engines. In this work, focus was given on the knocking combustion characteristics of operation with pure n-butanol as well as a blend fuel with 20% volume content of n-butanol (Bu20), which was investigated experimentally in a direct-injection spark ignition (DISI) single cylinder engine. Operation condition is fixed at a constant engine speed of 1500 r/min, using three throttle openings with stoichiometric air–fuel ratio. Spark timing was swept to achieve different knocking levels. The results of n-butanol and Bu20 were benchmarked against those obtained by the research octane number (RON) 92 commercial gasoline. Compared with the baseline fuel gasoline, neat n-butanol shows better anti-knock ability with more advanced knock limited spark timing, whereas slightly deteriorative knock resistance can be found for Bu20. It is hypothesized Bu20 has higher end gas temperature due to its higher brake mean effective pressure (BMEP) and faster burning rate compared with gasoline, which indicates the knock tendency depends not only on the fuel octane number, but also on the factors that affect the end gas thermodynamic state. The heavier knock propensity of Bu20 is furthermore confirmed by its more advanced knock onset and higher peak oscillation pressure. Results of fast fourier transform (FFT) indicate the knocking oscillation frequencies are mainly determined by the

  8. Knocking Down Snrnp200 Initiates Demorphogenesis of Rod Photoreceptors in Zebrafish

    Directory of Open Access Journals (Sweden)

    Yuan Liu

    2015-01-01

    Full Text Available Purpose. The small nuclear ribonucleoprotein 200 kDa (SNRNP200 gene is a fundamental component for precursor message RNA (pre-mRNA splicing and has been implicated in the etiology of autosomal dominant retinitis pigmentosa (adRP. This study aims to determine the consequences of knocking down Snrnp200 in zebrafish. Methods. Expression of the Snrnp200 transcript in zebrafish was determined via whole mount in situ hybridization. Morpholino oligonucleotide (MO aiming to knock down the expression of Snrnp200 was injected into zebrafish embryos, followed by analyses of aberrant splicing and expression of the U4/U6-U5 tri-small nuclear ribonucleoproteins (snRNPs components and retina-specific transcripts. Systemic changes and retinal phenotypes were further characterized by histological study and immunofluorescence staining. Results. Snrnp200 was ubiquitously expressed in zebrafish. Knocking down Snrnp200 in zebrafish triggered aberrant splicing of the cbln1 gene, upregulation of other U4/U6-U5 tri-snRNP components, and downregulation of a panel of retina-specific transcripts. Systemic defects were found correlated with knockdown of Snrnp200 in zebrafish. Only demorphogenesis of rod photoreceptors was detected in the initial stage, mimicking the disease characteristics of RP. Conclusions. We conclude that knocking down Snrnp200 in zebrafish could alter regular splicing and expression of a panel of genes, which may eventually trigger rod defects.

  9. (p, α) reactions: knock-on(out) or pick-up

    International Nuclear Information System (INIS)

    Gadioli, E.

    1983-01-01

    Nothwithstanding the great lot of data collected starting from the beginning of fifties, it cannot be said that a good degree of knowledge about the (p, α) reaction mechanism has been reached. Experimental data are usually interpreted or on the basis of a pure pick-up or knock-on(out) mechanism, though many results suggest the importance of both mechanism

  10. The Effects of Engine Speed and Mixture Temperature on the Knocking Characteristics of Several Fuels

    Science.gov (United States)

    Lee, Dana W

    1940-01-01

    Six 100-octane and two 87-octane aviation engine fuels were tested in a modified C.F.R. variable-compression engine at 1,500, 2,000 and 2,500 rpm. The mixture temperature was raised from 50 to 300 F in approximately 50 degree steps and, at each temperature, the compression ratio was adjusted to give incipient knock as shown by a cathode ray indicator. The results are presented in tabular form. The results are analyzed on the assumption that the conditions which determine whether a given fuel will knock are the maximum values of density and temperature reached by the burning gases. A maximum permissible density factor, proportional to the maximum density of the burning gases just prior to incipient knock, and the temperature of the burning gases at that time were computed for each of the test conditions. Values of the density factors were plotted against the corresponding end-gas temperatures for the three engine speeds and also against engine speed for several and end-gas temperatures. The maximum permissible density factor varied only slightly with engine speed but decreased rapidly with an increase in the end-gas temperature. The effect of changing the mixture temperature was different for fuels of different types. The results emphasize the desirability of determining the anti knock values of fuels over a wide range of engine and intake-air conditions rather that at a single set of conditions.

  11. Hematopoiesis in 5-Fluorouracil-Treated Adenosine A(3) Receptor Knock-Out Mice

    Czech Academy of Sciences Publication Activity Database

    Hofer, Michal; Pospíšil, Milan; Dušek, L.; Hoferová, Zuzana; Komůrková, Denisa

    2015-01-01

    Roč. 64, č. 2 (2015), s. 255-262 ISSN 0862-8408 Institutional support: RVO:68081707 Keywords : Adenosine A(3) receptor knock-out mice * Hematopoiesis * 5-fluorouracil-induced hematotoxicity Subject RIV: BO - Biophysics Impact factor: 1.643, year: 2015

  12. "When Do I Knock on the Hotel Room Door?": The MLA Conference Job Interview.

    Science.gov (United States)

    Emmerson, Richard K.

    1995-01-01

    Offers advice to potential interviewees attending an MLA conference. Cautions the interviewee to arrive for the appointment early, but not to knock until the time of the appointment. Advises interviewees to answer questions briefly and to let the committee set the pace of the interview. (PA)

  13. Physicochemical effects of varying fuel composition on knock characteristics of natural gas mixtures

    NARCIS (Netherlands)

    Gersen, Sander; van Essen, Martijn; van Dijk, Gerco; Levinsky, Howard

    2014-01-01

    The physicochemical origins of how changes in fuel composition affect autoignition of the end gas, leading to engine knock, are analyzed for a natural gas engine. Experiments in a lean-burn, high-speed medium-BMEP gas engine are performed using a reference natural gas with systematically varied

  14. Relevant feature set estimation with a knock-out strategy and random forests

    DEFF Research Database (Denmark)

    Ganz, Melanie; Greve, Douglas N; Fischl, Bruce

    2015-01-01

    unintuitive and difficult to determine. In this article, we propose a novel MVPA method for group analysis of high-dimensional data that overcomes the drawbacks of the current techniques. Our approach explicitly aims to identify all relevant variations using a "knock-out" strategy and the Random Forest...

  15. A NEW METHOD FOR CHARACTERIZING THE KNOCK RESISTANCE OF LNG FUELS USED IN THE TRANSPORTATION MARKET

    NARCIS (Netherlands)

    Levinsky, Howard; Gersen, Sander; van Essen, Martijn; van Dijk, Gerco

    2014-01-01

    To ensure that the engines to be used in LNG-fueled vehicles are matched with the expected variations in fuel composition, the knock resistance of the fuel must be determined unambiguously. Rather than rely on empirical methods using gas mixtures and “standard” engines traditionally employed for

  16. Downy mildew of Double Knock Out® rose caused by Peronospora sparsa in Maryland

    Science.gov (United States)

    Roses are one of the most popular and economically important ornamental plants worldwide. In the last 17 years, Knock Out® roses (Rosa x 'Radtko') have been widely used in public and private gardens across the U.S. due to their disease resistance, self-cleaning, drought tolerance and multiple-bloomi...

  17. Knock-out of a mitochondrial sirtuin protects neurons from degeneration in Caenorhabditis elegans.

    Science.gov (United States)

    Sangaletti, Rachele; D'Amico, Massimo; Grant, Jeff; Della-Morte, David; Bianchi, Laura

    2017-08-01

    Sirtuins are NAD⁺-dependent deacetylases, lipoamidases, and ADP-ribosyltransferases that link cellular metabolism to multiple intracellular pathways that influence processes as diverse as cell survival, longevity, and cancer growth. Sirtuins influence the extent of neuronal death in stroke. However, different sirtuins appear to have opposite roles in neuronal protection. In Caenorhabditis elegans, we found that knock-out of mitochondrial sirtuin sir-2.3, homologous to mammalian SIRT4, is protective in both chemical ischemia and hyperactive channel induced necrosis. Furthermore, the protective effect of sir-2.3 knock-out is enhanced by block of glycolysis and eliminated by a null mutation in daf-16/FOXO transcription factor, supporting the involvement of the insulin/IGF pathway. However, data in Caenorhabditis elegans cell culture suggest that the effects of sir-2.3 knock-out act downstream of the DAF-2/IGF-1 receptor. Analysis of ROS in sir-2.3 knock-out reveals that ROS become elevated in this mutant under ischemic conditions in dietary deprivation (DD), but to a lesser extent than in wild type, suggesting more robust activation of a ROS scavenging system in this mutant in the absence of food. This work suggests a deleterious role of SIRT4 during ischemic processes in mammals that must be further investigated and reveals a novel pathway that can be targeted for the design of therapies aimed at protecting neurons from death in ischemic conditions.

  18. Effect of Timing and Location of Hotspot on Super Knock during Pre-ignition

    KAUST Repository

    Jaasim, Mohammed; Hernandez Perez, Francisco; Vedharaj, S.; Vallinayagam, R.; Dibble, Robert W.; Im, Hong G.

    2017-01-01

    Pre-ignition in SI engine is a critical issue that needs addressing as it may lead to super knock event. It is widely accepted that pre-ignition event emanates from hot spot(s) that can be anywhere inside the combustion chamber. The location

  19. Musical Tale as a Reading Comprehension Resource in the Classroom

    Directory of Open Access Journals (Sweden)

    Lucía Martínez Vázquez

    2017-11-01

    Full Text Available Reading comprehension is a complex process, whose teaching involves multiple factors, as highlighted by Psychology, Didactics of languages, and others disciplines. Nevertheless, theoretical frameworks need to be applied by means of innovative practices and resources. The aim of this work is to present an innovation implemented in 2016-2017 in the third year of primary school, in the frame of an action-research, with the objective of reinforcing the learning of reading. In order to cope whit the comprehension difficulties involved in attention and concentration abilities, a didactic intervention was designed with the musical tale as a resource. Different approaches to this sort of text, integrated in diverse activities, facilitated the learning of active listening of tales, expressing reading, and guided the attention of readers to metacognitive strategies. The experience allows better identify some difficulties in the reading process, and prove the usefulness of the musical tale, as a meaningful resource to support the teaching and learning of reading.

  20. Who jumps the highest? Anthropometric and physiological correlations of vertical jump in youth elite female volleyball players.

    Science.gov (United States)

    Nikolaidis, Pantelis T; Gkoudas, Konstantinos; Afonso, José; Clemente-Suarez, Vicente J; Knechtle, Beat; Kasabalis, Stavros; Kasabalis, Athanasios; Douda, Helen; Tokmakidis, Savvas; Torres-Luque, Gema

    2017-06-01

    The aim of the present study was to examine the relationship of vertical jump (Abalakov jump [AJ]) with anthropometric and physiological parameters in youth elite female volleyball players. Seventy-two selected volleyball players from the region of Athens (age 13.3±0.7 years, body mass 62.0±7.2 kg, height 171.5±5.7 cm, body fat 21.2±4.5%), classified into quartiles according to AJ performance (group A, 21.4-26.5 cm; group B, 26.8-29.9 cm; group C, 30.5-33.7 cm; group D, 33.8-45.9 cm), performed a series of physical fitness tests. AJ was correlated with anthropometric (age at peak height velocity [APHV]: r=0.38, Pvolleyball players that jumped the highest were those who matured later than others.

  1. A Transcription Activator-Like Effector (TALE) Toolbox for Genome Engineering

    Science.gov (United States)

    Sanjana, Neville E.; Cong, Le; Zhou, Yang; Cunniff, Margaret M.; Feng, Guoping; Zhang, Feng

    2013-01-01

    Transcription activator-like effectors (TALEs) are a class of naturally occurring DNA binding proteins found in the plant pathogen Xanthomonas sp. The DNA binding domain of each TALE consists of tandem 34-amino acid repeat modules that can be rearranged according to a simple cipher to target new DNA sequences. Customized TALEs can be used for a wide variety of genome engineering applications, including transcriptional modulation and genome editing. Here we describe a toolbox for rapid construction of custom TALE transcription factors (TALE-TFs) and nucleases (TALENs) using a hierarchical ligation procedure. This toolbox facilitates affordable and rapid construction of custom TALE-TFs and TALENs within one week and can be easily scaled up to construct TALEs for multiple targets in parallel. We also provide details for testing the activity in mammalian cells of custom TALE-TFs and TALENs using, respectively, qRT-PCR and Surveyor nuclease. The TALE toolbox described here will enable a broad range of biological applications. PMID:22222791

  2. Engineering DNA Backbone Interactions Results in TALE Scaffolds with Enhanced 5-Methylcytosine Selectivity.

    Science.gov (United States)

    Rathi, Preeti; Witte, Anna; Summerer, Daniel

    2017-11-08

    Transcription activator-like effectors (TALEs) are DNA major-groove binding proteins widely used for genome targeting. TALEs contain an N-terminal region (NTR) and a central repeat domain (CRD). Repeats of the CRD selectively recognize each one DNA nucleobase, offering programmability. Moreover, repeats with selectivity for 5-methylcytosine (5mC) and its oxidized derivatives can be designed for analytical applications. However, both TALE domains also nonspecifically interact with DNA phosphates via basic amino acids. To enhance the 5mC selectivity of TALEs, we aimed to decrease the nonselective binding energy of TALEs. We substituted basic amino acids with alanine in the NTR and identified TALE mutants with increased selectivity. We then analysed conserved, DNA phosphate-binding KQ diresidues in CRD repeats and identified further improved mutants. Combination of mutations in the NTR and CRD was highly synergetic and resulted in TALE scaffolds with up to 4.3-fold increased selectivity in genomic 5mC analysis via affinity enrichment. Moreover, transcriptional activation in HEK293T cells by a TALE-VP64 construct based on this scaffold design exhibited a 3.5-fold increased 5mC selectivity. This provides perspectives for improved 5mC analysis and for the 5mC-conditional control of TALE-based editing constructs in vivo.

  3. TALE activators regulate gene expression in a position- and strand-dependent manner in mammalian cells.

    Science.gov (United States)

    Uhde-Stone, Claudia; Cheung, Edna; Lu, Biao

    2014-01-24

    Transcription activator-like effectors (TALEs) are a class of transcription factors that are readily programmable to regulate gene expression. Despite their growing popularity, little is known about binding site parameters that influence TALE-mediated gene activation in mammalian cells. We demonstrate that TALE activators modulate gene expression in mammalian cells in a position- and strand-dependent manner. To study the effects of binding site location, we engineered TALEs customized to recognize specific DNA sequences located in either the promoter or the transcribed region of reporter genes. We found that TALE activators robustly activated reporter genes when their binding sites were located within the promoter region. In contrast, TALE activators inhibited the expression of reporter genes when their binding sites were located on the sense strand of the transcribed region. Notably, this repression was independent of the effector domain utilized, suggesting a simple blockage mechanism. We conclude that TALE activators in mammalian cells regulate genes in a position- and strand-dependent manner that is substantially different from gene activation by native TALEs in plants. These findings have implications for optimizing the design of custom TALEs for genetic manipulation in mammalian cells. Copyright © 2013 Elsevier Inc. All rights reserved.

  4. Simulation research on the effect of cooled EGR, supercharging and compression ratio on downsized SI engine knock

    Science.gov (United States)

    Shu, Gequn; Pan, Jiaying; Wei, Haiqiao; Shi, Ning

    2013-03-01

    Knock in spark-ignition(SI) engines severely limits engine performance and thermal efficiency. The researches on knock of downsized SI engine have mainly focused on structural design, performance optimization and advanced combustion modes, however there is little for simulation study on the effect of cooled exhaust gas recirculation(EGR) combined with downsizing technologies on SI engine performance. On the basis of mean pressure and oscillating pressure during combustion process, the effect of different levels of cooled EGR ratio, supercharging and compression ratio on engine dynamic and knock characteristic is researched with three-dimensional KIVA-3V program coupled with pressure wave equation. The cylinder pressure, combustion temperature, ignition delay timing, combustion duration, maximum mean pressure, and maximum oscillating pressure at different initial conditions are discussed and analyzed to investigate potential approaches to inhibiting engine knock while improving power output. The calculation results of the effect of just cooled EGR on knock characteristic show that appropriate levels of cooled EGR ratio can effectively suppress cylinder high-frequency pressure oscillations without obvious decrease in mean pressure. Analysis of the synergistic effect of cooled EGR, supercharging and compression ratio on knock characteristic indicates that under the condition of high supercharging and compression ratio, several times more cooled EGR ratio than that under the original condition is necessarily utilized to suppress knock occurrence effectively. The proposed method of synergistic effect of cooled EGR and downsizing technologies on knock characteristic, analyzed from the aspects of mean pressure and oscillating pressure, is an effective way to study downsized SI engine knock and provides knock inhibition approaches in practical engineering.

  5. Effect of Timing and Location of Hotspot on Super Knock during Pre-ignition

    KAUST Repository

    Jaasim, Mohammed

    2017-03-28

    Pre-ignition in SI engine is a critical issue that needs addressing as it may lead to super knock event. It is widely accepted that pre-ignition event emanates from hot spot(s) that can be anywhere inside the combustion chamber. The location and timing of hotspot is expected to influence the knock intensity from a pre-ignition event. In this study, we study the effect of location and timing of hot spot inside the combustion chamber using numerical simulations. The simulation is performed using a three-dimensional computational fluid dynamics (CFD) code, CONVERGE™. We simulate 3-D engine geometry coupled with chemistry, turbulence and moving structures (valves, piston). G-equation model for flame tracking coupled with multi-zone model is utilized to capture auto-ignition (knock) and solve gas phase kinetics. A parametric study on the effect of hot spot timing and location inside the combustion chamber is performed. The hot spot timing considered are -180 CAD, -90 CAD and -30 CAD and the locations of the hot spots are in the center and two edges of the piston surfaces. Simulation results for normal combustion cycle are validated against the experimental data. The simulation results show great sensitivity to the hot spot timing, and the influence of local temperature gradient is noted to be significant. In case of early hot spot timing of -180 CAD, the pre-ignition event did not lead to super knock. Nevertheless, at late hot spot timing, super knock was realized. On the other hand, the effect of hot spot location on pre-ignition event depends on the geometry of the combustion chamber.

  6. The kick-in system: a novel rapid knock-in strategy.

    Science.gov (United States)

    Tomonoh, Yuko; Deshimaru, Masanobu; Araki, Kimi; Miyazaki, Yasuhiro; Arasaki, Tomoko; Tanaka, Yasuyoshi; Kitamura, Haruna; Mori, Fumiaki; Wakabayashi, Koichi; Yamashita, Sayaka; Saito, Ryo; Itoh, Masayuki; Uchida, Taku; Yamada, Junko; Migita, Keisuke; Ueno, Shinya; Kitaura, Hiroki; Kakita, Akiyoshi; Lossin, Christoph; Takano, Yukio; Hirose, Shinichi

    2014-01-01

    Knock-in mouse models have contributed tremendously to our understanding of human disorders. However, generation of knock-in animals requires a significant investment of time and effort. We addressed this problem by developing a novel knock-in system that circumvents several traditional challenges by establishing stem cells with acceptor elements enveloping a particular genomic target. Once established, these acceptor embryonic stem (ES) cells are efficient at directionally incorporating mutated target DNA using modified Cre/lox technology. This is advantageous, because knock-ins are not restricted to one a priori selected variation. Rather, it is possible to generate several mutant animal lines harboring desired alterations in the targeted area. Acceptor ES cell generation is the rate-limiting step, lasting approximately 2 months. Subsequent manipulations toward animal production require an additional 8 weeks, but this delimits the full period from conception of the genetic alteration to its animal incorporation. We call this system a "kick-in" to emphasize its unique characteristics of speed and convenience. To demonstrate the functionality of the kick-in methodology, we generated two mouse lines with separate mutant versions of the voltage-dependent potassium channel Kv7.2 (Kcnq2): p.Tyr284Cys (Y284C) and p.Ala306Thr (A306T); both variations have been associated with benign familial neonatal epilepsy. Adult mice homozygous for Y284C, heretofore unexamined in animals, presented with spontaneous seizures, whereas A306T homozygotes died early. Heterozygous mice of both lines showed increased sensitivity to pentylenetetrazole, possibly due to a reduction in M-current in CA1 hippocampal pyramidal neurons. Our observations for the A306T animals match those obtained with traditional knock-in technology, demonstrating that the kick-in system can readily generate mice bearing various mutations, making it a suitable feeder technology toward streamlined phenotyping.

  7. Neuromuscular adaptations to 4 weeks of intensive drop jump training in well-trained athletes

    DEFF Research Database (Denmark)

    Alkjær, Tine; Meyland, Jacob; Raffalt, Peter C

    2013-01-01

    This study examined the effects of 4 weeks of intensive drop jump training in well-trained athletes on jumping performance and underlying changes in biomechanics and neuromuscular adaptations. Nine well-trained athletes at high national competition level within sprinting and jumping disciplines...... participated in the study. The training was supervised and augmented feedback on performance was used to ensure maximal training intensity. The drop jumps were performed with minimal contact time and maximal jumping height. Assessment of performance during training showed effects of motor learning. Before...... and after the training intervention maximal isometric muscle strength, the biomechanics, muscle activity pattern of the lower extremities and the soleus H-reflex and V-wave during drop jumping were measured. Maximal jump height and performance index (PI) defined as jumping height divided by contact time...

  8. Afrika Statistika ISSN 2316-090X Jump Resonance in Wind-Felled ...

    African Journals Online (AJOL)

    jump function. Duffing's model, describing function and Chebyshev polynomials were used .... this study to develop polynomial growth equation for plantains and plantain jump resonance ..... New technologies to increase root health and crop.

  9. Acute Improvement of Vertical Jump Performance After Isometric Squats Depends on Knee Angle and Vertical Jumping Ability.

    Science.gov (United States)

    Tsoukos, Athanasios; Bogdanis, Gregory C; Terzis, Gerasimos; Veligekas, Panagiotis

    2016-08-01

    Tsoukos, A, Bogdanis, GC, Terzis, G, and Veligekas, P. Acute improvement of vertical jump performance after isometric squats depends on knee angle and vertical jumping ability. J Strength Cond Res 30(8): 2250-2257, 2016-This study examined the acute effects of maximum isometric squats at 2 different knee angles (90 or 140°) on countermovement jump (CMJ) performance in power athletes. Fourteen national-level male track and field power athletes completed 3 main trials (2 experimental and 1 control) in a randomized and counterbalanced order 1 week apart. Countermovement jump performance was evaluated using a force-plate before and 15 seconds, 3, 6, 9, and 12 minutes after 3 sets of 3 seconds maximum isometric contractions with 1-minute rest in between, from a squat position with knee angle set at 90 or 140°. Countermovement jump performance was improved compared with baseline only in the 140° condition by 3.8 ± 1.2% on the 12th minute of recovery (p = 0.027), whereas there was no change in CMJ height in the 90° condition. In the control condition, there was a decrease in CMJ performance over time, reaching -3.6 ± 1.2% (p = 0.049) after 12 minutes of recovery. To determine the possible effects of baseline jump performance on subsequent CMJ performance, subjects were divided into 2 groups ("high jumpers" and "low jumpers"). The baseline CMJ values of "high jumpers" and "low jumpers" differed significantly (CMJ: 45.1 ± 2.2 vs. 37.1 ± 3.9 cm, respectively, p = 0.001). Countermovement jump was increased only in the "high jumpers" group by 5.4 ± 1.4% (p = 0.001) and 7.4 ± 1.2% (p = 0.001) at the knee angles of 90 and 140°, respectively. This improvement was larger at the 140° angle (p = 0.049). Knee angle during isometric squats and vertical jumping ability are important determinants of the acute CMJ performance increase observed after a conditioning activity.

  10. P-glycoprotein interaction with risperidone and 9-OH-risperidone studied in vitro, in knock-out mice and in drug-drug interaction experiments

    DEFF Research Database (Denmark)

    Ejsing, Thomas B.; Pedersen, Anne D.; Linnet, Kristian

    2005-01-01

    P-glycoprotein, risperidone, nortriptyline, cyclosporine A, drug-drug interaction, blood-brain barrier, knock-out mice......P-glycoprotein, risperidone, nortriptyline, cyclosporine A, drug-drug interaction, blood-brain barrier, knock-out mice...

  11. The prevalence of ski jumping among pupils in the first triad of primary school

    OpenAIRE

    Vtič, Maja

    2016-01-01

    As one of the most widespread sports discipline in Slovenia, ski jumping has a long tradition. Ski jumping is a competitive sport at which recreational engagement is not possible because of its special features and specifics. It is one of the basic sports activities for the development of children's motor skills, since ski jumping requires an integrated training of the trainee. Ski jumping is basically a winter sport, whereas in the summer season, it has also become increasingly present with ...

  12. Nordic ski jumping fatalities in the United States: a 50-year summary.

    Science.gov (United States)

    Wright, J R

    1988-06-01

    Nordic ski-jumping fatalities are rare events. Six jumping fatalities have occurred in the United States during the past 50 years. The fatality rate for nordic ski jumping, estimated to be roughly 12 fatalities/100,000 participants annually, appears to be within the range of fatality rates for other "risky" outdoor sports. Cervical fractures appear to be the most frequent fatal ski-jumping injury.

  13. Ski jump takeoff performance predictions for a mixed-flow, remote-lift STOVL aircraft

    Science.gov (United States)

    Birckelbaw, Lourdes G.

    1992-01-01

    A ski jump model was developed to predict ski jump takeoff performance for a short takeoff and vertical landing (STOVL) aircraft. The objective was to verify the model with results from a piloted simulation of a mixed flow, remote lift STOVL aircraft. The prediction model is discussed. The predicted results are compared with the piloted simulation results. The ski jump model can be utilized for basic research of other thrust vectoring STOVL aircraft performing a ski jump takeoff.

  14. Asymptotic Behaviour and Extinction of Delay Lotka-Volterra Model with Jump-Diffusion

    OpenAIRE

    Dan Li; Jing’an Cui; Guohua Song

    2014-01-01

    This paper studies the effect of jump-diffusion random environmental perturbations on the asymptotic behaviour and extinction of Lotka-Volterra population dynamics with delays. The contributions of this paper lie in the following: (a) to consider delay stochastic differential equation with jumps, we introduce a proper initial data space, in which the initial data may be discontinuous function with downward jumps; (b) we show that the delay stochastic differential equation with jumps associate...

  15. Variability of Jump Kinetics Related to Training Load in Elite Female Basketball

    OpenAIRE

    Jan Legg; David B. Pyne; Stuart Semple; Nick Ball

    2017-01-01

    The purpose of this study was to quantify changes in jump performance and variability in elite female basketballers. Junior and senior female representative basketball players (n = 10) aged 18 ± 2 years participated in this study. Countermovement jump (CMJ) data was collected with a Gymaware™ optical encoder at pre-, mid-, and post-season time points across 10 weeks. Jump performance was maintained across the course of the full season (from pre to post). Concentric peak velocity, jump height,...

  16. The world price of jump and volatility risk

    NARCIS (Netherlands)

    Driessen, J.J.A.G.; Maenhout, P.

    2013-01-01

    We study international integration of markets for jump and volatility risk, using index option data for the main global markets. To explain the cross-section of expected option returns we focus on return-based multi-factor models. For each market separately, we provide evidence that volatility and

  17. Motoneuron membrane potentials follow a time inhomogeneous jump diffusion process

    DEFF Research Database (Denmark)

    Jahn, Patrick; Berg, Rune W; Hounsgaard, Jørn

    2011-01-01

    models can only be applied over short time windows. However, experimental data show varying time constants, state dependent noise, a graded firing threshold and time-inhomogeneous input. In the present study we build a jump diffusion model that incorporates these features, and introduce a firing...

  18. The Hydraulic Jump: Finding Complexity in Turbulent Water

    Science.gov (United States)

    Vondracek, Mark

    2013-01-01

    Students who do not progress to more advanced science disciplines in college generally do not realize that seemingly simple physical systems are--when studied in detail--more complex than one might imagine. This article presents one such phenomenon--the hydraulic jump--as a way to help students see the complexity behind the seemingly simple, and…

  19. Berman-Konsowa principle for reversible Markov jump processes

    NARCIS (Netherlands)

    Hollander, den W.Th.F.; Jansen, S.

    2013-01-01

    In this paper we prove a version of the Berman-Konsowa principle for reversible Markov jump processes on Polish spaces. The Berman-Konsowa principle provides a variational formula for the capacity of a pair of disjoint measurable sets. There are two versions, one involving a class of probability

  20. Jump as Far as You Can [Problem Solvers: Solutions

    Science.gov (United States)

    Yigit, Melike; Bofferding, Laura; Warnock, Miranda

    2014-01-01

    The How Far Do You Think You Can Jump? activity (see EJ1174770) was completed in three different contexts: an after-school mathematics enrichment program at Woodland and Country Schools in Weston, Massachusetts; a small-group pull-out of second graders at Wren Elementary in Piedmont, South Carolina; and a family math night in Lafayette, Indiana.…

  1. Trading price jump clusters in foreign exchange markets

    Czech Academy of Sciences Publication Activity Database

    Novotný, Jan; Petrov, D.; Urga, G.

    2015-01-01

    Roč. 24, June (2015), s. 66-92 ISSN 1386-4181 R&D Projects: GA ČR(CZ) GA14-27047S Institutional support: RVO:67985998 Keywords : price jumps * foreign exchange markets * trading Subject RIV: AH - Economics Impact factor: 1.726, year: 2015

  2. Autotomy, tail regeneration and jumping ability in Cape dwarf ...

    African Journals Online (AJOL)

    Many studies have examined the effect of caudal autotomy on speed and ... Although longer jumps were less likely to be successful (i.e. the animal ... Their tails may, however, be important to control their landing as well as their locomotion on ...

  3. Structural estimation of jump-diffusion processes in macroeconomics

    DEFF Research Database (Denmark)

    Posch, Olaf

    2009-01-01

    This paper shows how to solve and estimate a continuous-time dynamic stochastic general equilibrium (DSGE) model with jumps. It also shows that a continuous-time formulation can make it simpler (relative to its discrete-time version) to compute and estimate the deep parameters using the likelihoo...

  4. Considering Jumping Ship? A Pirate Looks at Retirement

    Science.gov (United States)

    Kilpatrick, Bob G.

    2011-01-01

    If you're like me, a "senior" faculty member at a public state university facing significant budget cuts, recently you've probably thought about leaving your current position for another faculty position in a different state. A possible reason for considering jumping ship is envisioning a clearer picture of your retirement as it nears on…

  5. Contribution to the experimental study of the hydraulic jump in ...

    African Journals Online (AJOL)

    The purpose of this study is to study experimentally the hydraulic jump evolving in a symmetric trapezoidal channel with a positive slope, requires the use of an experimental protocol, and to find experimental relations linking the characteristics of the formed projection. The experimental study investigated the variation of the ...

  6. Delayed frost growth on jumping-drop superhydrophobic surfaces.

    Science.gov (United States)

    Boreyko, Jonathan B; Collier, C Patrick

    2013-02-26

    Self-propelled jumping drops are continuously removed from a condensing superhydrophobic surface to enable a micrometric steady-state drop size. Here, we report that subcooled condensate on a chilled superhydrophobic surface are able to repeatedly jump off the surface before heterogeneous ice nucleation occurs. Frost still forms on the superhydrophobic surface due to ice nucleation at neighboring edge defects, which eventually spreads over the entire surface via an interdrop frost wave. The growth of this interdrop frost front is shown to be up to 3 times slower on the superhydrophobic surface compared to a control hydrophobic surface, due to the jumping-drop effect dynamically minimizing the average drop size and surface coverage of the condensate. A simple scaling model is developed to relate the success and speed of interdrop ice bridging to the drop size distribution. While other reports of condensation frosting on superhydrophobic surfaces have focused exclusively on liquid-solid ice nucleation for isolated drops, these findings reveal that the growth of frost is an interdrop phenomenon that is strongly coupled to the wettability and drop size distribution of the surface. A jumping-drop superhydrophobic condenser minimized frost formation relative to a conventional dropwise condenser in two respects: preventing heterogeneous ice nucleation by continuously removing subcooled condensate, and delaying frost growth by limiting the success of interdrop ice bridge formation.

  7. Spatiotemporal characteristics of motor actions by blind long jump athletes.

    Science.gov (United States)

    Torralba, Miguel Angel; Padullés, José María; Losada, Jose Luis; López, Jose Luis

    2017-01-01

    Blind people depend on spatial and temporal representations to perform activities of daily living and compete in sport. The aim of this study is to determine the spatiotemporal characteristics of long jumps performed by blind athletes and compare findings with those reported for sighted athletes. We analysed a sample of 12 male athletes competing in the F11 Long Jump Finals at the Paralympic Games in London 2012. Performances were recorded using four high-speed cameras, and speeds were measured using a radar speed gun. The images were processed using validated image analysis software. The long jump run-up is shorter in blind athletes than in sighted athletes. We observed statistically significant differences for body centre of mass velocity and an increase in speed over the last three strides prior to take-off, contrasting with reports for sighted athletes and athletes with less severe visual impairment, who maintain or reduce their speed during the last stride. Stride length for the last three strides was the only spatial characteristic that was not significantly associated with effective jump distance. Blind long jumpers extend rather than shorten their last stride. Contact time with the take-off board is longer than that reported for sighted athletes. The actions of blind long jumpers, unlike those without disabilities, do not vary their leg actions during the final runway approach for optimal placement on the take-off board.

  8. Environmentally transmitted parasites: Host-jumping in a heterogeneous environment.

    Science.gov (United States)

    Caraco, Thomas; Cizauskas, Carrie A; Wang, Ing-Nang

    2016-05-21

    Groups of chronically infected reservoir-hosts contaminate resource patches by shedding a parasite׳s free-living stage. Novel-host groups visit the same patches, where they are exposed to infection. We treat arrival at patches, levels of parasite deposition, and infection of the novel host as stochastic processes, and derive the expected time elapsing until a host-jump (initial infection of a novel host) occurs. At stationarity, mean parasite densities are independent of reservoir-host group size. But within-patch parasite-density variances increase with reservoir group size. The probability of infecting a novel host declines with parasite-density variance; consequently larger reservoir groups extend the mean waiting time for host-jumping. Larger novel-host groups increase the probability of a host-jump during any single patch visit, but also reduce the total number of visits per unit time. Interaction of these effects implies that the waiting time for the first infection increases with the novel-host group size. If the reservoir-host uses resource patches in any non-uniform manner, reduced spatial overlap between host species increases the waiting time for host-jumping. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Spatiotemporal characteristics of motor actions by blind long jump athletes

    Science.gov (United States)

    Torralba, Miguel Angel; Padullés, José María; Losada, Jose Luis; López, Jose Luis

    2017-01-01

    Background Blind people depend on spatial and temporal representations to perform activities of daily living and compete in sport. Objective The aim of this study is to determine the spatiotemporal characteristics of long jumps performed by blind athletes and compare findings with those reported for sighted athletes. Methods We analysed a sample of 12 male athletes competing in the F11 Long Jump Finals at the Paralympic Games in London 2012. Performances were recorded using four high-speed cameras, and speeds were measured using a radar speed gun. The images were processed using validated image analysis software. Results The long jump run-up is shorter in blind athletes than in sighted athletes. We observed statistically significant differences for body centre of mass velocity and an increase in speed over the last three strides prior to take-off, contrasting with reports for sighted athletes and athletes with less severe visual impairment, who maintain or reduce their speed during the last stride. Stride length for the last three strides was the only spatial characteristic that was not significantly associated with effective jump distance. Blind long jumpers extend rather than shorten their last stride. Contact time with the take-off board is longer than that reported for sighted athletes. Conclusion The actions of blind long jumpers, unlike those without disabilities, do not vary their leg actions during the final runway approach for optimal placement on the take-off board. PMID:29018542

  10. Barbara McClintock, Jumping Genes, and Transposition

    Science.gov (United States)

    McClintock Honored * Woman of Science * Educational Material * Resources with Additional Information Barbara McClintock's remarkable life spanned the history of genetics in the twentieth century. ... [T]he science of Dedicate Famous Scientist Stamps ... Woman of Science: McClintock, Barbara and the Jumping Genes, 4,000

  11. RunJumpCode: An Educational Game for Educating Programming

    Science.gov (United States)

    Hinds, Matthew; Baghaei, Nilufar; Ragon, Pedrito; Lambert, Jonathon; Rajakaruna, Tharindu; Houghton, Travers; Dacey, Simon

    2017-01-01

    Programming promotes critical thinking, problem solving and analytic skills through creating solutions that can solve everyday problems. However, learning programming can be a daunting experience for a lot of students. "RunJumpCode" is an educational 2D platformer video game, designed and developed in Unity, to teach players the…

  12. University–industry collaboration: Jump-starting innovation | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-10-06

    Oct 6, 2010 ... In Costa Rica, researchers and business have found innovative ways to ... To jump-start these collaborations, IDRC is supporting research teams in 12 ... steel company recently tried to license a type of steel easy to mould into ...

  13. Plastic strain and flux jumps in hard and composite superconductors

    International Nuclear Information System (INIS)

    Maksimov, I.L.; Mints, R.G.

    1981-01-01

    A study is made into the effect of the critical current density dependence upon the value of plastic strain on the critical state stability in hard and composite superconductors under conditions of plastic yield of the material. Criteria of the critical state stability relative to the jointly developing magnetic flux jumps and plastic strain jerks, are found. (author)

  14. The Jump Training Program. In Season Conditioning for Women's Basketball.

    Science.gov (United States)

    Hannam, Sue; And Others

    1988-01-01

    Women athletes have been successful in maintaining and/or increasing their conditioning and vertical jump levels when they participate in the in-season circuit training program described in this article. An exercise guide, sample individual score card, and photos of women practicing the exercises are included. (IAH)

  15. Kinetics analysis of step and jump forward lunge among badminton ...

    African Journals Online (AJOL)

    This study was conducted to determine and compare the kinetics during step forward lunge (SFL) and jump forward lunge (JFL) in badminton. Fifteen university badminton players (mean age = 22.07 ± 1.39 years old) were recruited and were assigned to perform SFL and JFL while holding a badminton racquet using their ...

  16. Estimation and prediction under local volatility jump-diffusion model

    Science.gov (United States)

    Kim, Namhyoung; Lee, Younhee

    2018-02-01

    Volatility is an important factor in operating a company and managing risk. In the portfolio optimization and risk hedging using the option, the value of the option is evaluated using the volatility model. Various attempts have been made to predict option value. Recent studies have shown that stochastic volatility models and jump-diffusion models reflect stock price movements accurately. However, these models have practical limitations. Combining them with the local volatility model, which is widely used among practitioners, may lead to better performance. In this study, we propose a more effective and efficient method of estimating option prices by combining the local volatility model with the jump-diffusion model and apply it using both artificial and actual market data to evaluate its performance. The calibration process for estimating the jump parameters and local volatility surfaces is divided into three stages. We apply the local volatility model, stochastic volatility model, and local volatility jump-diffusion model estimated by the proposed method to KOSPI 200 index option pricing. The proposed method displays good estimation and prediction performance.

  17. The Jumping Ring and Lenz's Law--An Analysis

    Science.gov (United States)

    Bostock-Smith, J. M.

    2008-01-01

    Lenz's law is sometimes invoked to explain the behaviour of the jumping, or levitating, ring. This is shown to be incomplete, and an alternative explanation using Faraday's laws and circuit analysis is offered. This leads to the choice of optimum material and dimensions for the ring. (Contains 1 table and 4 figures.)

  18. Kinematic Analysis of the Standing Long Jump in Children 6- to 12-Years-Old

    Science.gov (United States)

    Fernandez-Santos, Jorge R.; Gonzalez-Montesinos, Jose Luis; Ruiz, Jonatan R.; Jiménez-Pavón, David; Castro-Piñero, Jose

    2018-01-01

    The purpose of this study was to analyze the kinematic variables that determine the performance of the standing long jump in children 6- to 12-years-old. There were 121 healthy children (58 girls) recorded while they performed the standing long jump test. All kinematic variables showed a significant correlation with calculated jump distance and…

  19. Gender bias in jumping kinetics in National Collegiate Athletic Association Division I basketball players.

    Science.gov (United States)

    Walsh, Mark S; Waters, Jeff A; Böhm, Harald; Potteiger, Jeff A

    2007-08-01

    The purposes of this study are to examine gender differences in the contribution of the arm swing to jump height in men and women basketball players and to examine the role of upper-body strength in the contribution of arm swing to jump height. National Collegiate Athletic Association Division I basketball players (men n = 13, women n = 12) performed 4 jumping movements: squat jumps with hands on hips (SNA) and with arm swings (SA) and countermovement jumps with hands on hips and with arm swings (CMA). Differences were found between the jump heights of men and women. Use of the arms increased the jump height of men more than women. Compared with the SNA, the SA allowed an increase of 7 cm (23%) for men and 4 cm (17%) for women. The CMA allowed for an increase of 10 cm (30%) for men and 6 cm (24%) for women. General upper-body strength measures did not correlate strongly with the effect of arms on jumping, but peak power did. As in previous studies, peak power had a high correlation with jumping performance. These results show that the arm swing contributes significantly to jump performance in both men and women basketball players and that strength training for jumping should focus on power production and lifting exercises that are jump specific.

  20. Effect of a neuromuscular training program on the kinetics and kinematics of jumping tasks.

    Science.gov (United States)

    Chappell, Jonathan D; Limpisvasti, Orr

    2008-06-01

    Altered motor control strategies are a proposed cause of the female athlete's increased risk for noncontact anterior cruciate ligament injury. Injury prevention programs have shown promising results in decreasing the incidence of anterior cruciate ligament injury. To evaluate the effect of the Kerlan-Jobe Orthopaedic Clinic Modified Neuromuscular Training Program on the biomechanics of select jumping tasks in the female collegiate athlete. Controlled laboratory study. Thirty female National Collegiate Athletic Association Division I soccer and basketball players performed vertical jump, hopping tests, and 2 jumping tasks (drop jump and stop jump). All subjects completed a 6-week neuromuscular training program with core strengthening and plyometric training. Three-dimensional motion analysis and force plate data were used to compare the kinetics and kinematics of jumping tasks before and after training. Dynamic knee valgus moment during the stance phase of stop jump tasks decreased after completion of the neuromuscular training program (P = .04), but differences were not observed for the drop jump. Initial knee flexion (P = .003) and maximum knee flexion (P = .006) angles increased during the stance phase of drop jumps after training, but differences were not observed for the stop jump. The athletes showed improved performance in vertical jump (P training program improved select athletic performance measures and changed movement patterns during jumping tasks in the subject population. The use of this neuromuscular training program could potentially modify the collegiate athlete's motion strategies, improve performance, and lower the athlete's risk for injury.