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Sample records for julije domac dr

  1. Julije Domac - život i djelo

    OpenAIRE

    Inić, Suzana

    2011-01-01

    Predmet istraživanja ovog rada je cjelovit, sustavan i originalan prikaz života i djela Julija Domca, znanstvenika, pedagoga, dekana Filozofskog fakulteta (1901./02.), rektora Sveučilišta u Zagrebu (1911./12.), praktičnog farmaceuta i čovjeka koji je dao izniman doprinos utemeljenju i razvitku moderne farmacije u Hrvatskoj. Temeljitim istraživanjem arhivske građe u Zagrebu, Vinkovcima, Osijeku i Đakovu, kao i privatnog arhiva obitelji Domac omogućen je cjelovit uvid u genealogiju i biografiju...

  2. Large Customers (DR Sellers)

    Energy Technology Data Exchange (ETDEWEB)

    Kiliccot, Sila [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2011-10-25

    State of the large customers for demand response integration of solar and wind into electric grid; openADR; CAISO; DR as a pseudo generation; commercial and industrial DR strategies; California regulations

  3. Drømmejobbet

    DEFF Research Database (Denmark)

    Harrebye, Silas

    2012-01-01

    Medarbejdere vil i fremtiden også kunne arbejde, mens de sover. Virksomheder tilbyder snart deres ansatte interne kurser i ‘lucid dreaming’. Disse giver mulighed for, at man i sine drømme bliver bevidst om, at man drømmer og således kan manipulere dem. Det skal nu udnyttes. Management...

  4. Dr. Daniel Carter

    Science.gov (United States)

    1998-01-01

    Dr. Daniel Carter, president of New Century Pharmaceuticals in Huntsville, Al, is one of three principal investigators in NASA's microgravity protein crystal growth program. Dr. Carter's experties is in albumins. Albumins are proteins in the bloodstream that transport materials, drugs, nutrients, and wastes. Photo credit: NASA/Marshall Space Flight Center

  5. Dr. Daniel Carter

    Science.gov (United States)

    1998-01-01

    Dr. Daniel Carter, president of New Century Pharmaceuticals in Huntsville, Al, is one of three principal investigators in NASA's microgravity protein crystal growth program. Dr. Carter's experties is in albumins. Albumins are proteins in the bloodstream that transport materials, drugs, nutrients, and wastes. Photo credit: NASA/Marshall Space Flight Center

  6. Dr Math at your service

    CSIR Research Space (South Africa)

    Butgereit, L

    2012-10-01

    Full Text Available In this presentation the author explains how the Dr Math service works; how tutors are recruited to act as Dr Math; and how school pupils can reach Dr Math for help with their mathematics homework....

  7. Happy Birthday, Dr. Seuss!

    Science.gov (United States)

    Brodie, Carolyn S.

    2002-01-01

    Reports on the career of Theodor Seuss Geisel and suggests activities to celebrate his birthday. Lists selected children's books by Dr. Seuss, selected Seuss videos, Web sites, biographical resources, and biographical videos. (LRW)

  8. Dr.GEO

    Directory of Open Access Journals (Sweden)

    Francesca Campora

    2004-01-01

    Full Text Available Presentazione di Dr. Geo, un prodotto software Open Source progettato per lo studio interattivo della geometria euclidea piana e per un primo approccio ai fondamenti della programmazione in linguaggio Scheme.

  9. KODAK Directview DR Systems

    Directory of Open Access Journals (Sweden)

    Stefan Baum

    2007-08-01

    Full Text Available KODAK DIRECTVIEW DR 9500 System. The flexibility of a dual detector system in a unique, sin-gle detector design. The DR 9500 easily moves "around" the patient, making it ideal for all horizontal, upright and angled projections, and added convenience for patients - particularly those with limited mobility. "nKODAK DIRECTVIEW DR 7500 System New-generation system provides the ultimate in digital radiography flexibility. Modular components ena-ble you to easily configure a DR system to fit your space, applications, workflow - and budget."nHighest operator comfort:"n• Auto tracking (tube, table, wall stand, both direc-tions"n• Automatic, perpendicular centring to detectors center for table and wall stand"n• Auto positioning (choice of 16, customer programmable tube-detector positions"n• Manual or full motorised up and down motion and motorised detector tilt capability"n• Overhead tube system optional motorised, standard length rail system (5x3m"n• Floor mounted or with floor rails equipped DR 7500WM wall stand"n• Moveable, motorised table with floating top table"nScaleable: "n• degree of motorisation, degree of automatic func-tions"nKODAK DIRECTVIEW DR 3000 System This powerful multipurpose system is designed to handle a full range of general radiography procedures. With its simple design, space saving footprint, and advanced "ease of use" features, this system can enhance departmental workflow, productivity, and the quality of patient care.

  10. Drømmebilleder

    DEFF Research Database (Denmark)

    Fausing, Bent

    2014-01-01

    Bogen beskriver i en række intense analyser forbindelsen mellem ydre og indre billeder: altså mellem de moderne mediers billedverden og drømmens og erindringens indre billeder. I fokus for undersøgelsen er desuden kønnet, altså hvordan billeder viser, omformer eller skjuler kønnet, 'det andet', s...

  11. Drømmebilleder

    DEFF Research Database (Denmark)

    Fausing, Bent

    2014-01-01

    Bogen beskriver i en række intense analyser forbindelsen mellem ydre og indre billeder: altså mellem de moderne mediers billedverden og drømmens og erindringens indre billeder. I fokus for undersøgelsen er desuden kønnet, altså hvordan billeder viser, omformer eller skjuler kønnet, 'det andet', s...

  12. Dr. julio iribarne

    OpenAIRE

    Revista de la, Facultad de Medicina

    2011-01-01

    El Dr. lribarne fue profesor titular de Ginecología, dos veces Decano de la Facultad de Ciencias Médicas de Buenos Aires, uno de los profesores más ilustres, llamado el Decano de las reformas universitarias, escritor y sociólogo profundo conocidoy respetado en todos los centros científicos de Europa y del Nuevo Continente, director de la "Revista Médica Latino Americana". Lamentamos el fallecimiento de este colega que no solamente era una gloria del cuerpo médico argentino, sino de la América...

  13. Teaching Peace with Dr. Seuss.

    Science.gov (United States)

    Pace, Rosemarie; Podesta, Andrea

    1999-01-01

    Educators seeking novel ways to instill conflict-resolution skills in young children should consider Dr. Seuss, whose books provide a synthesis of fantasy and reality that works for teaching values endemic to peace education. This paper discusses how students can learn peace and educators can teach peace using Dr. Seuss books, examining steps to…

  14. From Mxit to Dr Math

    CSIR Research Space (South Africa)

    Botha, Adèle

    2013-02-01

    Full Text Available In 2007, Laurie Butgereit, a researcher at the CSIR Meraka Institute, started to use Mxit as a communication channel to tutor her son in mathematics. Her son and a number of his friends logged in, and Dr Math was born. At the inception of Dr Math...

  15. Dr Stanislaw Huskowski, Mayor of Wroclaw, Poland

    CERN Document Server

    Patrice Loïez

    2002-01-01

    Dr Stanislaw Huskowski, Mayor of Wroclaw, Poland visiting the ATLAS magnet assembly hall, building 180. From l to r: Mr Carlo Lamprecht, State Councillor, Dr Stanislaw Huskowski and Dr Peter Jenni, ATLAS Spokesperson

  16. Dr Stanislaw Huskowski, Mayor of Wroclaw, Poland

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    Dr Stanislaw Huskowski, Mayor of Wroclaw, Poland visiting the ATLAS magnet assembly hall, building 180 with Mr Carlo Lamprecht, State Councillor, Dr Stanislaw Huskowski and Dr Peter Jenni, ATLAS Spokesperson

  17. How Dr. Pierce Promoted Himself

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This article is about Dr. Raymond V Pierce who owned St. Vincent Island before it became a refuge. The doctor painted advertisements for his famous “Woman’s Tonic”...

  18. Dr. Millie Cleveland: chiropractic achiever.

    Science.gov (United States)

    Nash, J

    1998-06-01

    Dr. Mildred Genoa Allison-Cleveland, affectionately known as "Dr. Millie," was an important part of life at Cleveland Chiropractic College for over thirty years, serving first as a clerical assistant, then instructor, administrative assistant, and trusted right hand of her husband, Dr. Carl Cleveland, Jr. Yet Mildred Cleveland, like many other women who have helped the profession grow and survive over the years, has never been the subject of an article in print. In this paper, the author will strive to outline Dr. Mildred Cleveland's accomplishments, as well as to give the reader as clear a picture as possible of the woman who was the wife of one chiropractic pioneer and mother of another.

  19. Dr Luigi Orlando, Dr Sergio Ceccuzzi, Dr. Armando Sbrana, Europa Metalli, Italy, Dr Albert Scherger, Member of KM Europa Metal AG, Osnabr ck, Germany, Prof. Filippo Menzinger, Scientific Attaché, Permanent Mission of Italy in Geneva

    CERN Multimedia

    Patrice Loïez

    2001-01-01

    Photo 01: Dr Lyn Evans and Dr Luigi Orlando Photo 04: L. to r.: Dr Lyn Evans, Dr Luigi Orlando, Prof. Luciano Maiani and Prof. Filippo Menzinger Photo 06: L. to r.: Prof. Philippo Menzinger, Dr Armando Sbrana, Prof. Luciano Maiani, Dr Albert Scherger, Dr Lyn Evans, Dr Luigi Orlando, Dr Sergio Ceccuzzi, visiting the LHC superconducting magnet test hall, SM18

  20. Diabetic retinopathy (DR: everybody's business

    Directory of Open Access Journals (Sweden)

    David Yorston

    2011-09-01

    Full Text Available Diabetes is on the increase worldwide, due mainly to the rise in the number of people with type 2 diabetes. Type 2 diabetes is becoming more common because:* People are living longer, and diabetes is more prevalent in older people.* As people increasingly migrate to urban areas, exercise less, eat more, and eat less healthy food, more people are becoming obese – a primary cause of type 2 diabetes.Diabetes increases the risk of a range of eye diseases, including cataract, but the main cause of blindness associated with diabetes is diabetic retinopathy (DR. DR usually develops between ten and twenty years after the onset of diabetes, and develops faster when diabetes is undiagnosed and untreated.People with DR whose sight is at risk can be treated, most commonly with laser, to prevent visual impairment and blindness. Sadly, there is no treatment that can restore vision that has already been lost.

  1. Tribute to Dr Jacques Rogge

    DEFF Research Database (Denmark)

    Bourgois, Jan G; Dumortier, Jasmien; Callewaert, Margot

    2017-01-01

    the former President of the International Olympic Committee, he was also an orthopaedic surgeon and a keen sailor, competing at three Olympic Games. In 1972, in fulfilment of the requirements for the degree of Master in Sports Medicine, he was the first who studied a sailors' muscle activity by means......'A tribute to Dr J. Rogge' aims to systematically review muscle activity and muscle fatigue during sustained submaximal quasi-isometric knee extension exercise (hiking) related to Olympic dinghy sailing as a tribute to Dr Rogge's merits in the world of sports. Dr Jacques Rogge is not only...... in Sports Medicine at the Ghent University. Hiking is a critical bilateral and multi-joint movement during dinghy racing, accounting for >60% of the total upwind leg time. Hiking generates large stresses in the anterior muscles that cross the knee and hip joint. Hiking is considered as a quasi...

  2. Profile Interview: Dr Desiree Witte

    African Journals Online (AJOL)

    Dr Albert Schweitzer, with stories about his hospital in. Lambarene, now ... active cases of vaccine-preventable diseases in children living ... aid program between the Dutch and Malawi Governments. I ... the delivery protected from the inquisitive eyes from people ... (LSHTM) and the World Health Organization (WHO).

  3. Dr. John Marburger visits DESY

    CERN Multimedia

    2003-01-01

    Dr. John Marburger, Director of the United States Office of Science and Technology Policy, visited the research center DESY in Hamburg. The American physicist wanted to inform himself about the status of the TESLA X-ray laser and the TESLA linear collider as well as the international collaboration at DESY (1/2 page).

  4. In Memoriam Dr. M. Jacobs

    NARCIS (Netherlands)

    Kalkman, C.

    1983-01-01

    Dr. Marius Jacobs, a senior staff member of the Rijksherbarium, died suddenly on 28 April 1983, following a heart attack some days earlier. He was only 53 years old and his death came as a great shock, not only to his colleagues at our institute. Jacobs was a many-sided man with interests in many fi

  5. In Memoriam Dr. M. Jacobs

    NARCIS (Netherlands)

    Kalkman, C.

    1983-01-01

    Dr. Marius Jacobs, a senior staff member of the Rijksherbarium, died suddenly on 28 April 1983, following a heart attack some days earlier. He was only 53 years old and his death came as a great shock, not only to his colleagues at our institute. Jacobs was a many-sided man with interests in many fi

  6. Dr. Hermann otto Sleumer retired

    NARCIS (Netherlands)

    Steenis, van C.G.G.J.

    1971-01-01

    On March 1st, 1971, Dr. Hermann Otto Sleumer, senior staff member of the Rijksherbarium, retired on reaching the age of 65 years. I have expressly omitted to say ‘from active service’, because his work has gone on uninterruptedly and he even had objections against spending one afternoon, on Febr. 26

  7. Sproglige drømmerier

    DEFF Research Database (Denmark)

    Farø, Ken Joensen

    2015-01-01

    blev tidligere brugt i Danmarks Radio som pausesignal, afspillet på en spilledåse. Ak ja, det var dengang. Gå ind på nettet og lyt til den, hvis du ikke kender melodien. Det er national kulturarv. Mange bevingede ord indeholder en form af ”drøm(me)”, fx Martin Luther Kings ”I have a Dream”. Eller...

  8. Kubrick's Dr. Strangelove: A Guide to Study

    Science.gov (United States)

    Carringer, Robert

    1974-01-01

    Article provided an analysis of the films of Stanley Kubrick, credits for the film, Dr. Strangelove, a sequence outline of Dr. Strangelove and study questions relating to the film. It further made suggestions for additional reading. (RK)

  9. Obituary: Dr Dianne Johnson (1947-2012)

    CERN Document Server

    Hamacher, Duane W

    2014-01-01

    It is with great sadness that I report the passing of Dr Dianne Johnson in May 2012. Dr Johnson was a pivotal and important figure in the field of Australian cultural astronomy and in the campaign for Aboriginal rights.

  10. White Dwarfs in SDSS DR9 and DR10

    Science.gov (United States)

    Gentile Fusillo, Nicola Pietro; Gänsicke, Boris; Koester, Detlev

    2015-06-01

    Currently the largest catalogue of spectroscopically identified WDs is based on the 7th Data Release (DR) of the Sloan Digital Sky Survey and contains over 20000 WDs (Kleinman et al. 2013). However, only a fraction of all WDs in the photometric footprint of SDSS have been spectroscopically followed up. Using DR7 spectroscopy as a training sample, we developed a method to select high confidence photometric WD candidates. The novelty of our selection is that it allows us to assign to any object with multi-colour and proper motion data a well-defined "probability of being a white dwarf" (or a contaminant). Exploiting this selection method we compiled a catalogue (Gentile Fusillo et al. in prep) which currently covers the entire photometric footprint of SDSS, 14555sq deg, with a limiting magnitude of g ≤ 19. The catalogue contains over 20000 high-confidence WDs and WD candidates 11500 of which have not yet been followed up with Sloan spectroscopy. Even though, so far, our catalogue relies only SDSS we plan to extend the sky coverage as additional deep multi-colour large area surveys become available. DR10 includes over 1.4 million spectra taken with the new BOSS spectrograph, which improves over the original SDSS spectograph in both resolution and wavelength coverage, but has so far not been systematically mined for WD science. As part of this project, we also inspected over 8000 BOSS spectra of bright (g ≤ 19) colour selected sources and classified 1765 new WDs. We used this independent, spectroscopically confirmed sample to further validate our selection method. Finally we discuss possible application of our catalogue , focusing on the selection and follow up of 9 new DZs which show strong pollution from elements other than Ca and IR excess emission emission consistent with the presence of debris discs.

  11. Dr Jan Theodoor Henrard (with portrait)

    NARCIS (Netherlands)

    Goddijn, W.A.

    1946-01-01

    On October 16th 1946 Dr J. Th. Henrard will have reached the pensionable age of sixty five years. In accordance with the legal prescriptions he is due to take leave officially as keeper of the ”Rijksherbarium“. The present director, Prof. Dr H. J. Lam, invited me to write a short biography of Dr

  12. Dr Jan Theodoor Henrard (with portrait)

    NARCIS (Netherlands)

    Goddijn, W.A.

    1946-01-01

    On October 16th 1946 Dr J. Th. Henrard will have reached the pensionable age of sixty five years. In accordance with the legal prescriptions he is due to take leave officially as keeper of the ”Rijksherbarium“. The present director, Prof. Dr H. J. Lam, invited me to write a short biography of Dr Hen

  13. FOREWORD: Dr Trevor J Hicks Dr Trevor J Hicks

    Science.gov (United States)

    Goossens, Darren

    2009-03-01

    This issue of Journal of Physics: Condensed Matter has been assembled to recognize the valuable contribution of Dr Trevor J Hicks to the field of neutron scattering and magnetism. Trevor began his study of magnetism as a PhD student at Monash University in Melbourne in the early 1960s, working with Professor Jack Smith. From the very beginning magnetism in alloys, and disordered systems in general, became a key aspect of his career. After a postdoctoral position at Harwell working with Dr Graeme Low Trevor returned to Australia and took up a position with Monash. He soon became a key figure in developing the capability for neutron scattering using the HIFAR reactor at the Australian Atomic Energy Commission, now the Australian Nuclear Science and Technology Organisation, ANSTO. The instrumentation was always developed to further his studies of magnetism. The development of polarization analysis measurements of diffuse magnetic scattering, first using iron filters and then his own design of supermirror benders for beam polarization, took place through the 1970s, 1980s and into the 1990s. Throughout this time, Trevor mentored a series of PhD students and postdoctoral fellows, many of whom have contributed to this issue (and, indeed, guest edited it). As befits a scientist and university academic for whom teaching has always been important, Trevor has not only created a strong body of significant research, he has also made a major contribution to preparing several generations of neutron scattering scientists, and this issue reflects that. When I approached Journal of Physics: Condensed Matter with a proposal for an issue in honour of Trevor, the response was immediate and positive. It is with great pleasure that I present the result of that proposal. The great diversity of the content, all centred on neutron scattering and magnetism, reflects the breadth of Trevor's own career and of the scientists with whom he has interacted. Finally, I would like to make some

  14. Interview with Dr Anna Matamala

    Directory of Open Access Journals (Sweden)

    Lucinea Marcelino Villela

    2016-12-01

    Full Text Available In this interview, which took place in June 2016, Dr Anna Matamala described some details about her long professional experience in Audiovisual Translation, especially in dubbing from English into Catalan, and we talked about many other things like her interest in lexicography, her point of view on some contemporary topics in Audiovisual Translation Studies: the use of technology, the relation between AVT and Accessibility Studies, AVT and Filmmaking fields, the importance of keeping in touch with other countries and even continents outside Europe, and she also gave some advice to the new generation of Translation students.

  15. PCCF flow analysis -- DR Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Calkin, J.F.

    1961-04-26

    This report contains an analysis of PCCF tube flow and Panellit pressure relations at DR reactor. Supply curves are presented at front header pressures from 480 to 600 psig using cold water and the standard 0.236 inch orifice with taper down stream and the pigtail valve (plug or ball) open. Demand curves are presented for slug column lengths of 200 inches to 400 inches using 1.44 inch O.D. solid poison pieces (either Al or Pb-Cd) and cold water with a rear header pressure of 50 psig. Figure 1 is a graph of Panellit pressure vs. flow with the above supply and demand curves and clearly shows the effect of front header pressure and charge length on flow.

  16. Dr House, TV, and reality...

    Science.gov (United States)

    Lapostolle, Frédéric; Montois, Sylvie; Alhéritière, Armelle; De Stefano, Carla; Le Toumelin, Philippe; Adnet, Frédéric

    2013-02-01

    Medical practice in the media is usually far from reality. Thus, the viewer may be led astray. The world-famous fictional Dr House has to face a difficult diagnosis every week. His practice does not seem to reflect reality. The aim of this study was to assess the diagnosis strategy involved in this television program. An observer has previewed the 2011 season. The episode running time, the patient's age and sex, the list of all investigations and interventions, the final diagnosis, and the patient's outcome were collected. Number and proportion of French viewers for each episode were recorded. We analyzed 18 episodes. The median running time was 42.5 (42.1-43.2) minutes. Main patient characters were 12 men (66%) and 6 women (33%); the average age was 31 (22-38) years. There were 225 investigations or interventions reported, averaging 14 (9-15) per episode, representing one examination every 3.1 (2.9-4.8) minutes. The most frequently prescribed investigations were magnetic resonance imaging (MRI; 13; 72%), blood sample (11; 61%), and biopsy (10; 56%). The most frequent interventions were surgery, anti-infectious treatments, and steroid treatments (9 each; 50%). Two patients (11%) died. The median number of spectators was 8.4 (8.1-8.7) million, corresponding to 33% (33%-34%) of the French national audience. The population and the examination strategies used by Dr House were unrealistic. Because of this distortion, patients may not understand, nor accept the delay, the investigation choices, the intervention costs, risks, nor failures of a daily medical practice. Physicians should be aware of this "information bias." Copyright © 2013 Elsevier Inc. All rights reserved.

  17. Dr. von Braun Briefing Walt Disney

    Science.gov (United States)

    1965-01-01

    Dr. von Braun began his association with Walt Disney in the 1950s when the rocket scientist appeared in three Disney television productions related to the exploration of space. Years later, Dr. von Braun invited Disney and his associates to tour the Marshall Space Flight Center (MSFC) in Huntsville, Alabama. This photograph is dated April 13, 1965. From left are R.J. Schwinghamer from the MSFC, Disney, B.J. Bernight, and Dr. von Braun.

  18. In Memoriam: Dr. Frank John Fenner

    Centers for Disease Control (CDC) Podcasts

    2011-04-22

    This podcast reflects on one of the greatest pioneers in virology, Dr. Frank John Fenner. Dr. Frederick Murphy, a member of EID's editorial board and the Institute of Medicine, and professor of Pathology at the University of Texas Medical Branch in Galveston, shares professional and personal stories of Dr. Frank Fenner.  Created: 4/22/2011 by National Center for Emerging Zoonotic and Infectious Diseases (NCEZID).   Date Released: 4/26/2011.

  19. Homenaje al Dr. Eduardo Vargas Alvarado

    OpenAIRE

    Carlos Abarca Barrantes; Leslie Solano Calderón

    2003-01-01

    La Universidad Latina rinde homenaje al Dr. Eduardo Vargas Alvarado, Decano de la Facultad de Medicina de esta Universidad. El Dr. Eduardo VaIgas Alvarado desarrollo la Morgue Judicial, desde su inicio en de enero de 1965, y desde 1975 hasta su jubilación del Poder Judicial en 1992 fue el Jefe del Departamento de Medicina Legal. La Dra. Leslie Solano Calderón es la Jefa actual de dicho Departamento y junto con el Dr. Abarca, fueron discípulos de Don Eduardo. El Dr. Vargas ha escrito varios li...

  20. China's Investment Leade Dr, Alyce Su

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    @@ I. Professional Background Dr. Alyce Su specializes in investment managemeng, managing portfolios consisted of investment opportunities originated from China's growth and internationalization, both'outbound and inbound.

  1. Dr Andrea Granelli, Vice President, Telecom Italia

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    Photo 06: Dr Andrea Granelli, Chief Executive Officer, Telecom Italia Lab (second from right) visiting the LHC superconducting magnet test hall with (from left to right) M. Cecchi , F. Gagliardi and G. Cavallari. Photo 15: Dr Andrea Granelli, Chief Executive Officer, Telecom Italia Lab (left) visiting the LHC superconducting magnet test hall with (from left to right) M. Cecchi and G. Cavallari.

  2. Biography of Dr. Simao Nascimento de Sousa

    Digital Repository Service at National Institute of Oceanography (India)

    Sarkar, A.^red.

    the projects he has handled are the Coastal Ocean Monitoring and Prediction System (COMAPS) and Integrated Coastal and Marine Area Management Plan for Goa (ICMAM-Goa). Dr. de Sousa was a silent worker of high caliber with exceptional leadership qualities. Dr. A...

  3. Dr Valter Rukavina - amateur painter.

    Science.gov (United States)

    Glavocic, Daina

    2008-01-01

    In this essay Dr Valter Rukavina (Rijeka 1896-1972), excellent specialist in infectious diseases and professor of the Rijeka University School of Medicine, is presented as successful amateur painter. He had been refining his talent through relentless practice since the school days, complementing it with skills and advice from established painters he associated with. He favoured figurative, realistic and somewhat romantic expression for his themes such as coastal landscapes, marinas, Quarnero sceneries, still life in tempera or oil, and drawings in ink or sepia. Despite partial colour blindness, he successfully used colour. He featured in a number of group exhibitions such as that of amateur painters of Rijeka in 1950, of painters physicians of Yugoslavia (Zagreb, 1956), in the Second International Exhibition of Contemporary Art (Florence, 1964), exhibition of the Rijeka branch of the Croatian Association of Visual Artists (Belgrade, 1966), and the 1969 exhibition in Opatija. His native city hosted two one-man exhibitions, the first retrospective in 1971, while he was still alive, and the second posthumous in 2007, with a good selection of his life's work.

  4. Monocytic HLA DR antigens in schizophrenic patients.

    Science.gov (United States)

    Krause, Daniela; Wagner, Jenny; Matz, Judith; Weidinger, Elif; Obermeier, Michael; Riedel, Michael; Gruber, Rudolf; Schwarz, Markus; Mueller, Norbert

    2012-01-01

    A genetic association of specific human leukocyte antigens (HLA) DR genes and schizophrenia has recently been shown. These HLA play a fundamental role in the control of immune responses. Furthermore infectious agents have been proposed to be involved in the pathogenesis of schizophrenia. In this study we investigated the rate of HLA DR positive monocytes in schizophrenic patients compared to controls with a special focus on the adaption to in vitro stimulation with toll-like receptor ligands. Patients with schizophrenia and matched controls were included. For each individual, we evaluated the rate of HLA DR positive monocytes (either incubated at 37 °C or after stimulation with lipopolysaccharide or Poly I:C). We found a significantly higher percentage of schizophrenic patients with elevated HLA DR positive cells (p=0.045) as compared to controls. The adjustment rate from baseline levels of monocytic HLA DR positive cells to stimulation with Poly I:C was significantly lower in schizophrenic patients (p=0.038). The increased monocytic HLA DR in schizophrenic patients and the maladjustment of their monocytic HLA DR levels to an infectious stimulus might be a sign for a disturbed monocytic immune balance in schizophrenic individuals.

  5. Homenaje al Dr. Eduardo Vargas Alvarado

    Directory of Open Access Journals (Sweden)

    Carlos Abarca Barrantes

    2003-03-01

    Full Text Available La Universidad Latina rinde homenaje al Dr. Eduardo Vargas Alvarado, Decano de la Facultad de Medicina de esta Universidad. El Dr. Eduardo VaIgas Alvarado desarrollo la Morgue Judicial, desde su inicio en de enero de 1965, y desde 1975 hasta su jubilación del Poder Judicial en 1992 fue el Jefe del Departamento de Medicina Legal. La Dra. Leslie Solano Calderón es la Jefa actual de dicho Departamento y junto con el Dr. Abarca, fueron discípulos de Don Eduardo. El Dr. Vargas ha escrito varios libros de Medicina Legal, ha recibido múltiples reconocimientos por su labor en la Medicina Legal Latinoamericana y es el Presidente Honorario de la Asociación Costarricense de Medicina Forense. El Departamento de Medicina Legal y la Asociación Costarricense de Medicina Forense se han sumado a este justo y oportuno reconocimiento.The Latina University give honor to Dr. Eduardo Vargas Alvarado, Dean of the Medicine Faculty of this University. Dr. Vargas developed the Judicial Morgue, from its very beginning, January 1, of 1965; and from 1975 until his jubilation from the Judicial Power in 1992 was the Boss of the Legal Medicine Department. Dr. Leslie Solano Calderon, the actual Boss of this Department, and Dr. Abarca were disciples of Mr. Vargas. Dr. Vargas has written many books of Legal Medicine and has received many acknowledgements because of his legal medicine work in Latin America and is the Honorary President of the Costa Rican Forensic Medicine Association. The Legal Medicine Department and the Costa Rican Forensic Medicine Association are added to this just and opportune acknowledge.

  6. An Interview with Dr. Walter Lear

    Directory of Open Access Journals (Sweden)

    The Editors

    2009-03-01

    Full Text Available In this issue of the English version of Social Medicine we are publishing the first of several pamphlets loaned to us by the US Health Activism History Collection. To introduce this collection we travelled to Philadelphia on June 18, 2008 to interview Dr. Walter J. Lear. Dr Lear, born in 1923, is the person responsible for the collection. In a wide-ranging interview in his home Dr. Lear discussed his personal background, the origins and purpose of the collection, the impact of the McCarthy period on the US health left, as well as his vision for the future.

  7. Analysis of Coupling between DR and Microstrip

    Institute of Scientific and Technical Information of China (English)

    LIAO Juan; LIU Guanghu

    2003-01-01

    The coupling between dielectric resonator (DR) and microstrip is theoretically analyzed in this paper. The equivalent circuit and corresponding components' expression are achieved. Also, the formula of the coupling ratio is deduced, which is the critical parameter to calculate the values of components. The analysis of the paper can be used in modeling and strict design in DR applications such as dielectric resonator oscillators(DROs)and DR filters. At the end of the paper, an example of DRO design based on the analysis above is given. The coincidence between modulation and measure shows the significance of the paper.

  8. Obituary - Dr. A. Venkoba Rao

    Directory of Open Access Journals (Sweden)

    Ajai R. Singh

    2005-11-01

    Full Text Available I have to inform with great regret the sad demise of Dr Venkoba Rao, one of the senior most and highly esteemed psychiatrists this country has produced. His research work in psychiatry and medicine, as well as his work in philosophy and the human predicament, have been noteworthy indeed. He was a researcher and an academician of the highest order.It was always a great pleasure interacting with him. Both juniors and his peers will remember him with great regard and equal fondness. He never made himself difficult to approach, and was open to all positive inputs, from whatever source.He was highly appreciative of the work done by the Mens Sana Research Foundation too. I treasure the encouraging letter he wrote to us sometime back about the Mens Sana Monograph Psychiatry, Science, Religion and Health, of which here is an excerpt:The articles in general are of high standard and are very readable.....Imust tell you that your monograph makes an enjoyable and informative reading and my personal congratulations to you on your achievement.In fact, he was encouraging towards all efforts in the field of mental health.His wide knowledge of philosophy and Indian thought, coupled with active research interest in mainstream psychiatry, made him a unique presence in the field.His absence will be felt for a long long time indeed.But I have lived, and have not lived in vain;My mind may lose its force, my blood its fire,And my frame perish even in conquering pain:But there is that within me which shall tireTorture and Time, and breathe when I expire;Something unearthly, which they deem not of,Like the remembered tone of a mute lyre....Byron ( Childe Harold On behalf of the Mens Sana Editorial Board, our subscribers, readers, as well as the Mensanamonographs group, I offer our deepest condolences to his bereaved family.May his soul rest in peace.

  9. But Dr. Meisels Is Not Convinced.

    Science.gov (United States)

    Meisels, Samuel J.

    1987-01-01

    Commenting on the Gesell Institute's response to his original article concerning the Gesell assessments, Dr. Meisels continues to maintain that the Gesell readiness tests lack sufficient proof of validity. (BB)

  10. Dr. Irvin Yalom Discusses Group Psychotherapy.

    Science.gov (United States)

    Forester-Miller, Holly

    1989-01-01

    In this interview, Dr. Irvin Yalom, director of the Adult Psychiatry Clinic at Stanford University School of Medicine, discusses his beginnings as a group psychotherapist, current issues in group work, and the future of group work. (Author/TE)

  11. Dr. Shi Hanzhang's Experience in Treating Andropathy

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ Dr. Shi Hanzhang (施汉章) of Dongzhimen Hospital affiliated to Beijing University of Traditional Chinese Medicine is experienced in both teaching and clinical practice, especially in treating andropathy, such as sexual disorder, infertility, and hyperplasia of the prostate. The author has the honour to follow him for study and really learned a lot from him. A brief introduction to Dr. Shi's way of thinking in treatment is as follows.

  12. Implementing Python for DrRacket

    OpenAIRE

    Ramos, Pedro Palma; Leitão, António Menezes

    2014-01-01

    The Python programming language is becoming increasingly popular in a variety of areas, most notably among novice programmers. On the other hand, Racket and other Scheme dialects are considered excellent vehicles for introducing Computer Science concepts. This paper presents an implementation of Python for Racket and the DrRacket IDE. This allows Python programmers to use Racket libraries and vice versa, as well as using DrRacket's pedagogic features. In particular, it allows architects and d...

  13. Dr. Cheng Yichun's Experience in Treating Hyperthyroidism

    Institute of Scientific and Technical Information of China (English)

    Sun Fenglei; Feng Jianhua; Wang Xinzhong

    2006-01-01

    @@ Having been engaged in the TCM clinical practice for more than 40 years, Dr. Cheng Yichun from the Affiliated Hospital of Shandong University of TCM has rich experience in treating endocrine metabolic diseases. Authors have had the good fortune to follow Dr. Chen for 10 years. Following is his train of thought in diagnosing and treating hyperthyroidism and his prescriptions most in use for the disease.

  14. Structural basis of LaDR5, a novel agonistic anti-death receptor 5 (DR5 monoclonal antibody, to inhibit DR5/TRAIL complex formation

    Directory of Open Access Journals (Sweden)

    Qiao Chunxia

    2012-07-01

    Full Text Available Abstract Background As a member of the TNF superfamily, TRAIL could induce human tumor cell apoptosis through its cognate death receptors DR4 or DR5, which can induce formation of the death inducing signaling complex (DISC and activation of the membrane proximal caspases (caspase-8 or caspase-10 and mitochondrial pathway. Some monoclonal antibodies against DR4 or DR5 have been reported to have anti-tumor activity. Results In this study, we reported a novel mouse anti-human DR5 monoclonal antibody, named as LaDR5, which could compete with TRAIL to bind DR5 and induce the apoptosis of Jurkat cells in the absence of second cross-linking in vitro. Using computer-guided molecular modeling method, the 3-D structure of LaDR5 Fv fragment was constructed. According to the crystal structure of DR5, the 3-D complex structure of DR5 and LaDR5 was modeled using molecular docking method. Based on distance geometry method and intermolecular hydrogen bonding analysis, the key functional domain in DR5 was predicted and the DR5 mutants were designed. And then, three mutants of DR5 was expressed in prokaryotic system and purified by affinity chromatograph to determine the epitope of DR5 identified by LaDR5, which was consistent with the theoretical results of computer-aided analysis. Conclusions Our results demonstrated the specific epitope located in DR5 that plays a crucial role in antibody binding and even antineoplastic bioactivity. Meanwhile, revealed structural features of DR5 may be important to design or screen novel drugs agonist DR5.

  15. Dræb, dræb, dræb! Nej ... liiiige et øjeblik: De machiavelliske følelser i Game of Thrones

    DEFF Research Database (Denmark)

    Schubart, Rikke

    2013-01-01

    Blogindlæg om Machiavelliske følelser i HBO tv-serien Game of Thrones: "Dræb, dræb, dræb! Nej ... liiiige et øjeblik: De machiavelliske følelser i Game of Thrones"......Blogindlæg om Machiavelliske følelser i HBO tv-serien Game of Thrones: "Dræb, dræb, dræb! Nej ... liiiige et øjeblik: De machiavelliske følelser i Game of Thrones"...

  16. Geophysical survey of 105-DR Pluto Crib, 116-DR-4, 100-D Area

    Energy Technology Data Exchange (ETDEWEB)

    Bergstrom, K.A.

    1993-10-01

    The objective of this Geophysical Survey was to verify the location of the 105-DR Pluto Crib, 116-DR-4. A surface monument currently marks its location. The crib is 10 feet by 10 feet and 15 feet deep. Ground-Penetrating Radar was the geophysical method selected to conduct the investigation.

  17. Dr. David Syz, State Secretary for Economic Affairs, Switzerland

    CERN Multimedia

    Patrice Loïez

    2003-01-01

    Photo 01: Dr. David Syz (left) with Professor Roger Cashmore, Research Director for Collider Programmes.Photo 02: Dr. David Syz signing the VIP visitors' book, with Prof. Roger Cashmore.Photo 03: Dr. David Syz signing the VIP visitors' book.Photo 04: Handshake between Dr. David Syz (left) and Prof. Roger Cashmore.

  18. A Tribute to Dr. Willy Lens

    Directory of Open Access Journals (Sweden)

    Maarten Vansteenkiste

    2016-07-01

    Full Text Available Dr. Willy Lens, born on December 10th, 1943, passed away on August 29th, 2014. With his passing, the motivation community has lost a seminal member, a mentor, and a friend. Dr. Lens – a Fellow of the Association for Psychological Science and Founding Fellow of the American Educational Research Association – made fundamental contributions to the study of motivation both through his own work and through his caring and thoughtful mentorship of a large community of scholars. With this tribute, we want to honor Dr. Willy Lens’ significance to psychology and education as well as his positive influence, both personally and professionally, on the lives of dozens of scholars. With his contagious enthusiasm and caring mentorship, Willy was an example for our academic community and with this tribute we express our gratitude for the privilege to have collaborated with him.

  19. Response to the editorial by Dr Geraghty.

    Science.gov (United States)

    White, Peter D; Chalder, Trudie; Sharpe, Michael; Angus, Brian J; Baber, Hannah L; Bavinton, Jessica; Burgess, Mary; Clark, Lucy V; Cox, Diane L; DeCesare, Julia C; Goldsmith, Kimberley A; Johnson, Anthony L; McCrone, Paul; Murphy, Gabrielle; Murphy, Maurice; O'Dowd, Hazel; Potts, Laura; Walwyn, Rebacca; Wilks, David

    2017-08-01

    This article is written in response to the linked editorial by Dr Geraghty about the adaptive Pacing, graded Activity and Cognitive behaviour therapy; a randomised Evaluation (PACE) trial, which we led, implemented and published. The PACE trial compared four treatments for people diagnosed with chronic fatigue syndrome. All participants in the trial received specialist medical care. The trial found that adding cognitive behaviour therapy or graded exercise therapy to specialist medical care was as safe as, and more effective than, adding adaptive pacing therapy or specialist medical care alone. Dr Geraghty has challenged these findings. In this article, we suggest that Dr Geraghty's views are based on misunderstandings and misrepresentations of the PACE trial; these are corrected.

  20. An interview with Dr Barbara A. Carper.

    Science.gov (United States)

    Eisenhauer, Elizabeth R

    2015-01-01

    In 1978, Dr Barbara A. Carper's foundational work, "Fundamental Patterns of Knowing in Nursing," arguably created a paradigm shift in nursing. However, her voice has been absent from the nursing literature in recent years. I was privileged to conduct a personal interview with Dr Carper in 2014. The edited interview includes a synopsis of her background, career trajectory, sources of inspiration, and her perspective on the current state of nursing. She reaffirmed her passion for reflective nursing practice, the importance incorporating the arts and humanities into nursing education, and using an integrated approach with the patterns of knowing in nursing.

  1. In Memoriam- Prof. Dr. Andries Willem Lategan

    Directory of Open Access Journals (Sweden)

    S. P. Ligthelm

    1965-03-01

    Full Text Available Hierdie Curriculum Vitae sou voorgelees gewees het met die inougurele rede van wyle prof. dr. A. W. Lategan met die aanvaarding van 'n ereprofessoraat aan die P.U. vir C.H.O. op 29 Oktober 1965. Prof. Lategan is op 23 Oktober 1965 oor- lcde. Sy inougurele rede verskyn as ’n bylaag in hierdie uit- gawe.

  2. Dr. Strangelove and Irrational Collective Rationality

    Institute of Scientific and Technical Information of China (English)

    韩蕾

    2012-01-01

      Dr. Strangelove or: How I learned to Stop Worrying and Love the Bomb is a 1964 black comedy film with satire of arm races and nuclear scare by the director Stanley Kubrick. In the movie, irrational practice and ideologies manifest them⁃selves as collective rationality and result in the destruction of the earth.

  3. Dr. A.F.M. Reijnders, centenarian

    NARCIS (Netherlands)

    Bas, C.

    1999-01-01

    A few weeks ago a reprint was distributed of an interesting paper on the formation of spores by metamorphosis of basidia in fruiting bodies of Mycocalia and Scleroderma. That in itself was not so remarkable. But it is really a small miracle that this paper was written by Dr. A.F.M. Reijnders at the

  4. Dr D. F. van Slooten †

    NARCIS (Netherlands)

    Lam, H.J.

    1953-01-01

    On March 7, 1953 the Rijksherbarium suffered a severe loss by the sudden death of its honorary co-operator Dr. D. F. van Slooten, the wellknown specialist particularly of Dipterocarpaceae. To honour his memory the following lines may serve as an obituary note. Dirk Fok van Slooten was born in Amersf

  5. ["Allergy testing" with "Dr. Voll electroacupuncture"].

    Science.gov (United States)

    Bresser, H

    1993-06-01

    Electroacupuncture according to Dr. Voll (EAV) is one of the numerous unconventional methods propagated for allergy testing in Germany. From an experimental examination for "drug testing" of this method, it can be concluded that EAV is unsuitable for any form of allergy testing.

  6. Dr. Lutz Reichhoff zum 65. Geburtstag

    OpenAIRE

    Böhnert, Wolfgang; Schönbrodt, Robert

    2014-01-01

    Am 26. Oktober 2013 vollendete Dr. rer. nat. sc. Lutz Reichhoff sein 65. Lebensjahr. Alle die ihn näher kennen wissen, dass diese Jahreszahl noch lange nicht seinen Ruhestand einläuten wird. Wir nehmen dennoch gern diesen Tag zum Anlass, seine umfangreichen und vielfältigen Leistungen im beruflichen und ehrenamtlichen Wirken zu würdigen.

  7. Walt Disney and Dr. Wernher von Braun

    Science.gov (United States)

    1954-01-01

    Dr. Werhner von Braun, then Chief, Guided Missile Development Operation Division at Army Ballistic Missile Agency (ABMA) in Redstone Arsenal, Alabama, was visited by Walt Disney in 1954. In the 1950's, von Braun worked with Disney Studio as a technical director, making three films about space exploration for television. A model of the V-2 rocket is in background.

  8. Dr. S. J. van Ooststroom retired

    NARCIS (Netherlands)

    Steenis, van C.G.G.J.

    1971-01-01

    In January 1971 Dr. Simon Jan van Ooststroom, senior botanist of the Rijksherbarium, retired on reaching the age of 65, having been on the staff since November 1934. Though this event will to a certain extent change, but not interrupt, his work, it is nevertheless worth commemorating, as he has so

  9. Stop words for “Dr Math”

    CSIR Research Space (South Africa)

    Butgereit, L

    2011-05-01

    Full Text Available “Dr Math” is a facility where primary and secondary school pupils can use MXit on their cell phones to get help with their mathematics homework. Pupils use an abbreviated “MXit lingo” leaving out most vowels and substituting various numerals...

  10. Confessions of a Dr Math tutor

    CSIR Research Space (South Africa)

    Butgereit, L

    2015-06-01

    Full Text Available Mathematics look different on a small 3-inch screen of an inexpensive cell phone when compared to a 3-meter whiteboard in a mathematics classroom. Dr Math uses cell phone or mobile data "chat" technologies to assist primary and secondary school...

  11. Dr. Bakhuizen van den Brink retires

    NARCIS (Netherlands)

    Kalkman, C.

    1976-01-01

    On 11 September 1976 dr. Reinier Cornelis Bakhuizen van den Brink will reach the age of 65 and so he must retire from his position as a senior botanist at the Rijksherbarium. He has worked in our institute since December 1943, after having obtained his doctor’s degree in Utrecht. At the Rijksherbari

  12. Non-gyroscope DR and adaptive information fusion algorithm used in GPS/DR device

    Institute of Scientific and Technical Information of China (English)

    Li Qingli; Xue Yongqi; Shang Yanlei; Shi Pengfei

    2006-01-01

    In view of the problems existing in GPS, a non-gyroscope DR is introduced. The operating principle and the algorithm of the GPS/DR device are also presented. By operating measured data synthetically, linear observation equations are obtained for the information fusion algorithm. This approach avoids model error due to linearizing nonlinear observation equations in the conventional algorithm, so that the stability of information fusion algorithm is improved and computation expenses are reduced. Field running experiments show that satisfactory accuracy can be obtained by the proposed navigation model and algorithm for the non-gyroscope GPS/DR device.

  13. Combination of TRAIL with bortezomib shifted apoptotic signaling from DR4 to DR5 death receptor by selective internalization and degradation of DR4.

    Directory of Open Access Journals (Sweden)

    Maxim L Bychkov

    Full Text Available TRAIL (tumor necrosis factor-related apoptosis-inducing ligand mediates apoptosis in cancer cells through death receptors DR4 and DR5 preferring often one receptor over another in the cells expressing both receptors. Receptor selective mutant variants of TRAIL and agonistic antibodies against DR4 and DR5 are highly promising anticancer agents. Here using DR5 specific mutant variant of TRAIL--DR5-B we have demonstrated for the first time that the sensitivity of cancer cells can be shifted from one TRAIL death receptor to another during co-treatment with anticancer drugs. First we have studied the contribution of DR4 and DR5 in HCT116 p53+/+ and HCT116 p53-/- cells and demonstrated that in HCT116 p53+/+ cells the both death receptors are involved in TRAIL-induced cell death while in HCT116 p53-/- cells prevailed DR4 signaling. The expression of death (DR4 and DR5 as well as decoy (DcR1 and DcR2 receptors was upregulated in the both cell lines either by TRAIL or by bortezomib. However, combined treatment of cells with two drugs induced strong time-dependent and p53-independent internalization and further lysosomal degradation of DR4 receptor. Interestingly DR5-B variant of TRAIL which do not bind with DR4 receptor also induced elimination of DR4 from cell surface in combination with bortezomib indicating the ligand-independent mechanism of the receptor internalization. Eliminatory internalization of DR4 resulted in activation of DR5 receptor thus DR4-dependent HCT116 p53-/- cells became highly sensitive to DR5-B in time-dependent manner. Internalization and degradation of DR4 receptor depended on activation of caspases as well as of lysosomal activity as it was completely inhibited by Z-VAD-FMK, E-64 and Baf-A1. In light of our findings, it is important to explore carefully which of the death receptors is active, when sensitizing drugs are combined with agonistic antibodies to the death receptors or receptor selective variants of TRAIL to enhance

  14. Combination of TRAIL with bortezomib shifted apoptotic signaling from DR4 to DR5 death receptor by selective internalization and degradation of DR4.

    Science.gov (United States)

    Bychkov, Maxim L; Gasparian, Marine E; Dolgikh, Dmitry A; Kirpichnikov, Mikhail P

    2014-01-01

    TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) mediates apoptosis in cancer cells through death receptors DR4 and DR5 preferring often one receptor over another in the cells expressing both receptors. Receptor selective mutant variants of TRAIL and agonistic antibodies against DR4 and DR5 are highly promising anticancer agents. Here using DR5 specific mutant variant of TRAIL--DR5-B we have demonstrated for the first time that the sensitivity of cancer cells can be shifted from one TRAIL death receptor to another during co-treatment with anticancer drugs. First we have studied the contribution of DR4 and DR5 in HCT116 p53+/+ and HCT116 p53-/- cells and demonstrated that in HCT116 p53+/+ cells the both death receptors are involved in TRAIL-induced cell death while in HCT116 p53-/- cells prevailed DR4 signaling. The expression of death (DR4 and DR5) as well as decoy (DcR1 and DcR2) receptors was upregulated in the both cell lines either by TRAIL or by bortezomib. However, combined treatment of cells with two drugs induced strong time-dependent and p53-independent internalization and further lysosomal degradation of DR4 receptor. Interestingly DR5-B variant of TRAIL which do not bind with DR4 receptor also induced elimination of DR4 from cell surface in combination with bortezomib indicating the ligand-independent mechanism of the receptor internalization. Eliminatory internalization of DR4 resulted in activation of DR5 receptor thus DR4-dependent HCT116 p53-/- cells became highly sensitive to DR5-B in time-dependent manner. Internalization and degradation of DR4 receptor depended on activation of caspases as well as of lysosomal activity as it was completely inhibited by Z-VAD-FMK, E-64 and Baf-A1. In light of our findings, it is important to explore carefully which of the death receptors is active, when sensitizing drugs are combined with agonistic antibodies to the death receptors or receptor selective variants of TRAIL to enhance cancer treatment

  15. Dr. von Braun and Dr. Stuhlinger With a Model of the Nuclear-Electric Vehicles

    Science.gov (United States)

    2004-01-01

    In this photo, taken at the Walt Disney Studios in California, Dr. Wernher von Braun and Dr. Ernst Stuhlinger are shown discussing the concepts of nuclear-electric spaceships designed to undertake the mission to the planet Mars. As a part of the Disney 'Tomorrowland' series on the exploration of space, the nuclear-electric vehicles were shown in the last three television films, entitled 'Mars and Beyond,' which first aired in December 1957.

  16. Decommissioning of DR 1, Final report

    Energy Technology Data Exchange (ETDEWEB)

    Lauridsen, Kurt

    2006-01-15

    The report describes the decommissioning activities carried out at the 2kW homogeneous reactor DR 1 at Risoe National Laboratory. The decommissioning work took place from summer 2004 until late autumn 2005. The components with the highest activity, the core vessel the recombiner and the piping and valves connected to these, were dismantled first by Danish Decommissioning's own technicians. Demolition of the control rod house and the biological shield as well as the removal of the floor in the reactor hall was carried out by an external demolition contractor. The building was emptied and left for other use. Clearance measurements of the building showed that radionuclide concentrations were everywhere below the clearance limit set by the Danish nuclear regulatory authorities. Furthermore, measurements on the surrounding area showed that there was no contamination that could be attributed to the operation and decommissioning of DR 1. (au)

  17. [Homage to Professor Dr. Nicasio Etchepareborda].

    Science.gov (United States)

    1998-11-01

    During a solemn academic act, de Main Classroom of the Facultad de Odontologia de Buenos Aires was named after Prof. Dr. Nicasio Etchepareborda. He has been the first professor at the Escuela de Odontologia and its organizer, after having obtained his Dentistry degree at the Dental School of Paris, in 1882. The new school was founded in 1891, and its activities began the following year.

  18. This Is Not Dr. Conn's Aldosterone Anymore

    OpenAIRE

    Brown, Nancy J.

    2011-01-01

    In 1955, Dr. Jerome Conn described a patient with severe hypertension and hypokalemia and an aldosterone-secreting adenoma. The prevalence of hyperaldosteronism is increased among patients with obesity or resistant hypertension. Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers reduce the secretion of aldosterone, but with chronic treatment aldosterone concentrations “escape” back to baseline values. Mineralocorticoid receptor (MR) antagonism reduces mortality i...

  19. DR21 Main: A Collapsing Cloud

    OpenAIRE

    Kirby, Larry

    2008-01-01

    The molecular cloud, DR21 Main, is an example of a large-scale gravitational collapse about an axis near the plane of the sky where the collapse is free of major disturbances due to rotation or other effects. Using flux maps, polarimetric maps, and measurements of the field inclination by comparing the line widths of ion and neutral species, we estimate the temperature, mass, magnetic field, and the turbulent kinetic, mean magnetic, and gravitational potential energies, and present a 3D model...

  20. Gaia DR1 documentation Chapter 6: Variability

    Science.gov (United States)

    Eyer, L.; Rimoldini, L.; Guy, L.; Holl, B.; Clementini, G.; Cuypers, J.; Mowlavi, N.; Lecoeur-Taïbi, I.; De Ridder, J.; Charnas, J.; Nienartowicz, K.

    2017-02-01

    This chapter describes the photometric variability processing of the Gaia DR1 data. Coordination Unit 7 is responsible for the variability analysis of over a billion celestial sources. In particular the definition, design, development, validation and provision of a software package for the data processing of photometrically variable objects. Data Processing Centre Geneva (DPCG) responsibilities cover all issues related to the computational part of the CU7 analysis. These span: hardware provisioning, including selection, deployment and optimisation of suitable hardware, choosing and developing software architecture, defining data and scientific workflows as well as operational activities such as configuration management, data import, time series reconstruction, storage and processing handling, visualisation and data export. CU7/DPCG is also responsible for interaction with other DPCs and CUs, software and programming training for the CU7 members, scientific software quality control and management of software and data lifecycle. Details about the specific data treatment steps of the Gaia DR1 data products are found in Eyer et al. (2017) and are not repeated here. The variability content of the Gaia DR1 focusses on a subsample of Cepheids and RR Lyrae stars around the South ecliptic pole, showcasing the performance of the Gaia photometry with respect to variable objects.

  1. DR-Cloud: Multi-Cloud Based Disaster Recovery Service

    National Research Council Canada - National Science Library

    Yu Gu DongshengWang Ghuanyi Liu

    2014-01-01

    .... This paper presents a practical multi-cloud based disaster recovery service model: DR- Cloud. With DR-Cloud, resources of multiple cloud service providers can be utilized cooperatively by the disaster recovery service provider...

  2. Dr. William C. Harris, Director-General, Science Foundation Ireland

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    Photo 01: Dr William C. Harris, Director-General, Science Foundation Ireland (left) with R. Cashmore. Photos 02, 03: Dr William C. Harris, Director-General, Science Foundation Ireland signing the CERN guest book with R. Cashmore.

  3. Dr. Yu Wang, Director, Natural Science Division, National Science Council, Taiwan

    CERN Multimedia

    Patrice Loïez

    2001-01-01

    Photo 01: L. to r.: Dr. Philippe Bloch, CERN CMS ECAL Deputy Project Manager, Dr. Yu Wang, Dr. Etiennette Auffray, CERN, responsible of the CERN ECAL Regional Centre. Photo 02: L. to r.: Dr. Yu Wang, Dr. Philippe Bloch, Dr. Apollo GO, National Central University, Taiwan, Dr. Etiennette Auffray.

  4. Dr. David Syz, State Secretary for Economic Affairs, Switzerland

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Dr. David Syz, State Secretary for Economic Affairs, Switzerland, toured the assembly hall of the ATLAS experiment on a recent visit to CERN.Photos 01, 02: Dr. Peter Jenni, spokesperson for the ATLAS experiment (second from left), explains to Dr. David Syz (fourth from left) and accompanying visitors the process of integration of a 26-metre-long coil of the barrel toroid magnet system into its coil casing.Photo 03: Dr. Peter Jenni (extreme right) with Dr. David Syz (front row, fourth from right) behind a stack of 26-metre-long 'racetrack' coils awaiting integration into their coil casings.

  5. Prof. DR. F. C. Eloff - An appreciation

    Directory of Open Access Journals (Sweden)

    G de Graaff

    1984-12-01

    Full Text Available I have been requested to write an appreciation of the man to whom these proceedings of a symposium on the Kalahari Ecosystem are dedicated @ Prof. Dr. F. C. Eloff, or Fritz as he is popularly referred to. I undertook the task with some trepidation and the only claim to the honour to write this article may be the fact that I have known Professor Eloff since 1949 when I was a green-shanked first year veterinary student at the University of Pretoria where he lectured in zoology to the new students.

  6. An Interview with Dr.Joseph Hung

    Institute of Scientific and Technical Information of China (English)

    包天仁

    2007-01-01

    @@ Prof.Bao Tianren(Bao):Dr.Hung,thank you for joining us in the 2nd National English as a Foreign Language Teaching Conference for Primary and Secondary Teachers of English in Guangzhou.We organize this conference every year and the theme of this year is Approaches on Raising China's English Language Teaching and Learning Efficiency.The current ELT situation for primary and secondary students in China is rather ineffective.Students learn English for 3 years or more in primary schools,but when they upgrade in junior schools,most of them will have to study English from the very beginning again.

  7. Dr. Hans Chang, Director, Physics Research Committee, Stichting voor Fundamenteel Onderzoek der Materie (FOM), Dr. Joris Van Enst, Head of Science Policy Division, Ministry of Education, Culture and S cience, Dr. Jan Bezemer, NL Delegate CERN, Netherlands

    CERN Multimedia

    Patrice Loiez

    1999-01-01

    Dr. Hans Chang, Director, Physics Research Committee, Stichting voor Fundamenteel Onderzoek der Materie (FOM), Dr. Joris Van Enst, Head of Science Policy Division, Ministry of Education, Culture and S cience, Dr. Jan Bezemer, NL Delegate CERN, Netherlands

  8. Decommissioning of DR 2. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Strufe, N.

    2009-02-15

    This report describes the work of dismantling and demolishing reactor DR 2, the waste volumes generated, the health physical conditions and the clearance procedures used for removed elements and waste. Since the ultimate goal for the decommissioning project was not clearance of the building, but downgrading the radiological classification of the building with a view to converting it to further nuclear use, this report documents how the lower classification was achieved and the known occurrence of remaining activity. The report emphasises some of the deliberations made and describes the lessons learned through this decommissioning project. The report also intends to contribute towards the technical basis and experience basis for further decommissioning of the nuclear facilities in Denmark. (au)

  9. Generic Data Pipelining Using ORAC-DR

    Science.gov (United States)

    Allan, Alasdair; Jenness, Tim; Economou, Frossie; Currie, Malcolm J.; Bly, Martin J.

    A generic data reduction pipeline is, perhaps, the holy grail for data reduction software. We present work which sets us firmly on the path towards this goal. ORAC-DR is an online data reduction pipeline written by the Joint Astronomy Center (JAC) and the UK Astronomy Technology Center (ATC) and distributed as part of the Starlink Software collection (SSC). It is intended to run with a minimum of observer interaction, and is able to handle data from many different instruments, including SCUBA, CGS4, UFTI, IRCAM and Michelle, with support for IRIS2 and UIST under development. Recent work by Starlink in collaboration with the JAC has resulted in an increase in the pipeline's flexibility, opening up the possibility that it could be used for truly generic data reduction for data from any imaging, and eventually spectroscopic, detector.

  10. VIP Visit Her Excellency Dr Dalia Grybauskaite

    CERN Multimedia

    2016-01-01

    Her Excellency Dr Dalia Grybauskaite President Republic of Lithuania. Wednesday 20 January 2016. General introduction to CERN’s activities by CERN Director-General F. Gianotti. CERN Director-General introduces CMS Collaboration Deputy Spokesperson K. Borras and CMS Lithuanians A. Rinkevicius with V. Rapsevicius. Met by J. Shiers, IT Department Data Preservation Project Leader, and walk to 1st floor Data Centre Visit Point. CERN Data Centre Visit Point, 1st floor, building 513. View the robotic arms of the CERN IT data centre automated libraries (J. Shiers) CERN Computer Centre, building 513, level -1. Physics hands-on and virtual visit with a High School class in Lithuania (S. Schmeling) CERN S’cool Lab, building 143. Meeting with the Lithuanian community at CERN. Signature of the Guest Book with CERN Director-General witnessed by the Lithuanian community at CERN. Family photograph with the Lithuanian community at CERN.

  11. Dr Harold Frederick Shipman: an enigma.

    Science.gov (United States)

    Gunn, John

    2010-07-01

    Dr. Shipman was the worst known serial killer in British history, at least in terms of numbers of victims, and possibly the worst in world history, if politicians are excluded. He killed at least 215 patients and may have begun his murderous career at the age of 25, within a year of finishing his medical training. His case has had a profound impact on the practice of medicine in the United Kingdom. Was he a special case? What were the origins of this behaviour? Could the behaviour have been prevented? It is necessary to learn what we can from a few personal facts and largely circumstantial evidence. He withheld himself from any useful clinical investigation or treatment once he had been taken into custody. Could he have been treated at any stage?

  12. [Dr. John Baptiste Edouard Gélineau].

    Science.gov (United States)

    Janković, S; Susić, V; Sokić, D; Lević, Z

    1996-01-01

    With this brief review we honor the memory of the great French doctor Jean Baptiste Edouard Gélineau. Dr. Gélineau was born on December 23, 1828 at Blaye, Gironde, close to the Bordeaux region. His name is connected with the first clinical description of the disease for which he, both by the right of the primacy as well as ad valorem of his first two names, coined the name "narcolepsy". He was the first to notice the intrinsically evanescent symptoms of narcolepsy, such as excessive daytime somnolence, imperative sleep habits and cataplexy or "astasia" as he called it, and incorporate them into a single clinical syndrome. In 1881 Gélineau discussed Kaffe's case of "maladie du sommeil" as a proof of the existence of the new disease described a year before. As a good clinical observer Gélineau noticed the close relation of emotional engagement and astasia. His attitude was that narcolepsy was a nosologic entity, a disease sui generis, but admitted that it could appear purely as a symptom only. This was in discordance with the views in England where (in 1928) Dr. Samuel Alexander Kinnier Wilson repudiated such convictions; in 1930 Lhermitte still shared the same opinion. Gélineau differentiated narcolepsy from epilepsy with the elegance of clinical reasoning. Overall, Gélineau described three elements of the narcoleptic pentade. Sleep paralyses were first described by Mitchell in 1876, and were first attributed to narcolepsy by Wilson in 1928; in 1930 Lhermitte first described hypnapompic, and Daniels, in 1934, hypnagogic sleep paralysis. Hypnagogic hallucinations were described by Maury in 1848 and subsequently by de Saint Denis in 1867. In twenties they were thoroughly studiesed during the epidemic encephalitis and after the Big War in 1922 by Levy. The life story of Dr. Gélineau covers multivarious activities. As a young student of the Rochefort Navy Medical School he took part in the fight against colera which deluged the city of La Rochelle. In 1849 he

  13. Dr. Solco Tromp and the Tromp Award

    Science.gov (United States)

    Greene, J. Scott; Rietveld, Wop J.

    2017-09-01

    The Tromp Award is the highest honor awarded by the International Society of Biometeorology (ISB). The award acknowledges outstanding research in biometeorology by a scientist under the age of 35 and was established in conjunction with the Tromp Foundation and the ISB. In honor of the 60th anniversary of the ISB, this article will provide a brief summary of the life of Dr. Solco Tromp and of the six awardees of the Tromp Award since the inaugural issuance of the award in 1999. The Tromp Award was established in part to recognize and support the efforts of young biometeorological professionals. As the brief summary of the awardees and a few of their selected subsequent publications have shown, the ISB and the Tromp Award has proven effective at identifying and supporting promising young scientists.

  14. DR-model-based estimation algorithm for NCS

    Institute of Scientific and Technical Information of China (English)

    HUANG Si-niu; CHEN Zong-ji; WEI Chen

    2006-01-01

    A novel estimation scheme based on dead reckoning (DR) model for networked control system (NCS)is proposed in this paper.Both the detailed DR estimation algorithm and the stability analysis of the system are given.By using DR estimation of the state,the effect of communication delays is overcome.This makes a controller designed without considering delays still applicable in NCS Moreover,the scheme can effectively solve the problem of data packet loss or timeout.

  15. Goldie Brangman Remembers the Operation to Save Dr King.

    Science.gov (United States)

    Koch, Evan; Brangman, Goldie

    2015-12-01

    In September 1958 the Rev Dr Martin Luther King Jr was stabbed and nearly assassinated. Surgeons at Harlem Hospital in New York City removed a 17.8-cm (7-in)-long letter opener from Dr King's chest. Certified Registered Nurse Anesthetist Goldie Brangman remembers this event because she participated in Dr King's anesthetic. This article correlates Brangman's memories with published accounts of the event. It also places the event within the context of the modern civil rights movement that Dr King led.

  16. Enrico Fermi Awards Ceremony for Dr. Allen J. Bard and Dr. Andrew Sessler, February 2014 (Presentations, including remarks by Energy Secretary, Dr. Ernest Moniz)

    Energy Technology Data Exchange (ETDEWEB)

    Moniz, Ernest [U.S. Energy Secretary

    2014-02-03

    The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On February 3, 2014 it was conferred upon two exceptional scientists. The first to be recognized is Dr. Allen J. Bard, 'for international leadership in electrochemical science and technology, for advances in photoelectrochemistry and photocatalytic materials, processes, and devices, and for discovery and development of electrochemical methods including electrogenerated chemiluminescence and scanning electrochemical microscopy.' The other honoree is Dr. Andrew Sessler, 'for advancing accelerators as powerful tools of scientific discovery, for visionary direction of the research enterprise focused on challenges in energy and the environment, and for championing outreach and freedom of scientific inquiry worldwide.' Dr. Patricia Dehmer opened the ceremony, and Dr. Ernest Moniz presented the awards.

  17. Interview with Smithsonian NASM Spacesuit Curator Dr. Cathleen Lewis

    Science.gov (United States)

    Lewis, Cathleen; Wright, Rebecca

    2012-01-01

    Dr. Cathleen Lewis was interviewed by Rebecca Wright during the presentation of an "Interview with Smithsonian NASM Spacesuit Curator Dr. Cathleen Lewis" on May 14, 2012. Topics included the care, size, and history of the spacesuit collection at the Smithsonian and the recent move to the state-of-the-art permanent storage facility at the Udvar-Hazy facility in Virginia.

  18. Dr. Shawn Mehlenbacher 2012 Wilder Silver Medal Recipient

    Science.gov (United States)

    Dr. Shawn Mehlenbacher, Oregon State University, was awarded the 2012 Wilder Medal by the American Pomological Society for his contributions to hazelnut genetics and cultivar development. Dr. Mehlenbacher took over the leadership of the Oregon State University hazelnut breeding program in 1986 aft...

  19. Dr. E. Kits van Waveren (1906—1995)

    NARCIS (Netherlands)

    Bas, C.

    1996-01-01

    With the death on 3 September 1995 of Dr. E. Kits van Waveren, the Dutch mycologists lost one of their most prominent, internationally known amateurs, a specialist on the taxonomy of the genus Psathyrella and an ardent collector. Dr. Kits van Waveren, honorary staff member of the Rijksherbarium at L

  20. Dr. Praveen Chaudhari named director of Brookhaven National Laboratory

    CERN Document Server

    2003-01-01

    "Brookhaven Science Associates announced today the selection of Dr. Praveen Chaudhari as Director of the U.S. Department of Energy's Brookhaven National Laboratory. Dr. Chaudhari, who will begin his new duties on April 1, joins Brookhaven Lab after 36 years of distinguished service at IBM as a scientist and senior manager of research" (1 page).

  1. Celebrating the Life and Legacy of Dr. John Hope Franklin

    Science.gov (United States)

    Harris, Robert L., Jr.; Levering-Lewis, David; French, John D.; Wharton, Clifton R., Jr.

    2009-01-01

    Dr. John Hope Franklin chronicled the experiences of African-Americans like no one before him, forcing America to recognize Black history as American history. His contributions were innumerable and his impact was abiding. In celebration of his life and legacy, the authors profile the celebrated scholar and activist, Dr. John Hope Franklin.

  2. Efficacy of DR, CT and MRI in bone tumors

    Institute of Scientific and Technical Information of China (English)

    Yanjiao Zhang; Xuefeng Cui; Changcheng Li; Shenjiang Li

    2014-01-01

    Objective:The aim of the study was to investigate the ef icacy of digital radiography (DR), computed tomography (CT) and magnetic resonance imaging (MRI) in bone tumors. Methods:Fifty-five patients with histological y confirmed bone tumors underwent imaging examinations. Fifty-five patients were performed DR, 21 CT and 20 MRI. Results:DR of 51 pa-tients clearly revealed bone changes. DR of 40 patients wel showed marginal. Twenty tumors appeared periosteal reaction on DR and 19 calcification on DR. CT scan of 21 patients clearly depicted bone changes, marginal and calcification and CT scan of 8 revealed periosteal reaction. MRI scan of 20 patients al showed marginal and soft-tissue mass and bone marrow edema was prominent in 8 patients. Conclusion:DR is the first imaging approach for born tumors. CT wel reveal the extent and minute structure of the bone tumors, the extent, soft-tissue mass and bone marrow edema are more dramatical y demon-strated on MRI imaging. DR integrates with CT and MRI, is helpful in diagnosis of bone tumors.

  3. Dr. Lai Xinsheng's Experience in Acupuncture Treatment of Refractory Diseases

    Institute of Scientific and Technical Information of China (English)

    Lin Shaozhen; Lai Xinsheng; Duan Shumin

    2006-01-01

    @@ Having been engaged in teaching, clinical practice and research for many years, Dr. Lai Xinsheng is good at acupuncture and the combined acupuncture and medication therapy to treat refractory diseases with satisfactory therapeutic effect. Sample cases treated by Dr. Lai are selected as follows.

  4. Dr. Albert Carr--Science Educator 1930-2000

    Science.gov (United States)

    Lopez, Leslie

    2013-01-01

    The very first issue of "Educational Perspectives" was published in October of 1962. Dr. Albert Carr wrote one of the inaugural essays on the topic of current developments in science education, and he went on to write several other articles for the journal. This article shares why Dr. Albert Carr's colleagues remember him for his…

  5. Balance Between the Worlds: A Conversation with Dr. Richard Vedan

    Directory of Open Access Journals (Sweden)

    Carolyn B Kenny

    2015-11-01

    Full Text Available In this article, Dr. Richard Vedan, a Secwepmec, lodge keeper, and medical social worker converses with Dr. Carolyn Kenny about critical elements of medical ethnomusicology as seen and experienced through an Indigenous context. Dilemmas of individualism versus collectivism and isolation versus connectivity underlie the entire conversation. Relevant themes in the traditional use of music in Indigenous healing are discussed.

  6. SDSS DR7 White Dwarf Catalog

    CERN Document Server

    Kleinman, S J; Koester, D; Pelisoli, Ingrid; Peçanha, Viviane; Nitta, A; Costa, J E S; Krzesinski, J; Dufour, P; Lachapelle, F -R; Bergeron, P; Yip, Ching-Wa; Harris, Hugh C; Eisenstein, Daniel J; Althaus, L; Córsico, A

    2012-01-01

    We present a new catalog of spectroscopically-confirmed white dwarf stars from the Sloan Digital Sky Survey Data Release 7 spectroscopic catalog. We find 20,407 white dwarf spectra, representing 19,712 stars, and provide atmospheric model fits to 14,120 DA and 1011 DB white dwarf spectra from 12,843 and 923 stars, respectively. These numbers represent a more than factor of two increase in the total number of white dwarf stars from the previous SDSS white dwarf catalog based on DR4 data. Our distribution of subtypes varies from previous catalogs due to our more conservative, manual classifications of each star in our catalog, supplementing our automatic fits. In particular, we find a large number of magnetic white dwarf stars whose small Zeeman splittings mimic increased Stark broadening that would otherwise result in an overestimated log(g) if fit as a non-magnetic white dwarf. We calculate mean DA and DB masses for our clean, non-magnetic sample and find the DB mean mass is statistically larger than that for...

  7. SDSS DR7 WHITE DWARF CATALOG

    Energy Technology Data Exchange (ETDEWEB)

    Kleinman, S. J.; Nitta, A. [Gemini Observatory, 670 North A' ohoku Place, Hilo, HI 96720 (United States); Kepler, S. O.; Pelisoli, Ingrid; Pecanha, Viviane; Costa, J. E. S. [Instituto de Fisica, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS (Brazil); Koester, D. [Institut fuer Theoretische Physik und Astrophysik, Universitaet Kiel, D-24098 Kiel (Germany); Krzesinski, J. [Mt. Suhora Observatory, Pedagogical University of Cracow, ul. Podchorazych 2, 30-084 Cracow (Poland); Dufour, P.; Lachapelle, F.-R.; Bergeron, P. [Departement de Physique, Universite de Montreal, C. P. 6128, Succ. Centre-Ville, Montreal, Quebec H3C 3J7 (Canada); Yip, Ching-Wa [Department of Physics and Astronomy, The Johns Hopkins University, 3701 San Martin Drive, Baltimore, MD 21218 (United States); Harris, Hugh C. [United States Naval Observatory, Flagstaff Station, 10391 West Naval Observatory Road, Flagstaff, AZ 86001-8521 (United States); Eisenstein, Daniel J. [Harvard Smithsonian Center for Astrophysics, 60 Garden Street, MS 20, Cambridge, MA 02138 (United States); Althaus, L.; Corsico, A., E-mail: hch@nofs.navy.mil [Facultad de Ciencias Astronomicas y Geofisicas, Paseo del Bosque S/N, (1900) La Plata (Argentina)

    2013-01-15

    We present a new catalog of spectroscopically confirmed white dwarf stars from the Sloan Digital Sky Survey (SDSS) Data Release 7 spectroscopic catalog. We find 20,407 white dwarf spectra, representing 19,712 stars, and provide atmospheric model fits to 14,120 DA and 1011 DB white dwarf spectra from 12,843 and 923 stars, respectively. These numbers represent more than a factor of two increase in the total number of white dwarf stars from the previous SDSS white dwarf catalogs based on DR4 data. Our distribution of subtypes varies from previous catalogs due to our more conservative, manual classifications of each star in our catalog, supplementing our automatic fits. In particular, we find a large number of magnetic white dwarf stars whose small Zeeman splittings mimic increased Stark broadening that would otherwise result in an overestimated log g if fit as a non-magnetic white dwarf. We calculate mean DA and DB masses for our clean, non-magnetic sample and find the DB mean mass is statistically larger than that for the DAs.

  8. This is not Dr. Conn's aldosterone anymore.

    Science.gov (United States)

    Brown, Nancy J

    2011-01-01

    In 1955, Dr. Jerome Conn described a patient with severe hypertension and hypokalemia and an aldosterone-secreting adenoma. The prevalence of hyperaldosteronism is increased among patients with obesity or resistant hypertension. Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers reduce the secretion of aldosterone, but with chronic treatment aldosterone concentrations "escape" back to baseline values. Mineralocorticoid receptor (MR) antagonism reduces mortality in patients with heart disease who are already taking an ACE inhibitor and diuretic. In addition to affecting sodium and potassium homeostasis via classical MR-dependent pathways, aldosterone induces inflammation and causes cardiovascular remodeling and renal injury. Some of these effects involve MR-independent pathways. At the same time, ligands other than aldosterone can activate the MR. This paper reviews mechanism(s) for the proinflammatory and profibrotic effects of aldosterone and presents data indicating that endogenous aldosterone, acting at the MR, contributes to many of the pro-inflammatory and pro-fibrotic effects of angiotensin II in vivo.

  9. Carbon stars from LAMOST DR2 data

    CERN Document Server

    Ji, Wei; Liu, Chao; Luo, Ali; Zhao, Gang; Zhang, Bo

    2016-01-01

    In this work, we present the new catalog of carbon stars from the LAMOST DR2 catalog. In total, 894 carbon stars are identified from multiple line indices measured from the stellar spectra. Combining the CN bands in the red end with \\ctwo\\ and other lines, we are able to identify the carbon stars. Moreover, we also classify the carbon stars into spectral sub-types of \\ch, \\CR, and \\cn. These sub-types approximately show distinct features in the multi-dimensional line indices, implying that in the future we can use them to identify carbon stars from larger spectroscopic datasets. Meanwhile, from the line indices space, while the \\cn\\ stars are clearly separated from the others, we find no clear separation between \\CR\\ and \\ch\\ sub-types. The \\CR\\ and \\ch\\ stars seem to smoothly transition from one to another. This may hint that the \\CR\\ and \\ch\\ stars may not be different in their origins but look different in their spectra because of different metallicity. Due to the relatively low spectral resolution and low...

  10. Dr. Rudolph Binion: professor, mentor, psychohistorian.

    Science.gov (United States)

    Szaluta, Jacques

    2015-01-01

    As the title of my paper indicates, Dr. Rudolph Binion was my professor, mentor, and a leading psychohistorian. My paper in memoriam to Rudolph Binion is intended as both a retrospective and an introspective account of my relationship with him, as he had a pivotal influence on me when he was my professor at Columbia University. His help and influence continued after I left graduate school. In my paper I also deal with the enormous stresses of navigating through graduate school, for those students whose goal was to earn the Ph.D. degree. Some examinations were dreaded, For Example The "Examination in Subjects," popularly called the "Oral Exam." The "incubation" period was long indeed, frequently averaging nearly ten years, and it was an ordeal, as the rate of attrition was very high. There is then also the question of "ego strength" and that of "transference" toward the professor. Graduate school is indeed a long and strenuous challenge. I took a seminar in modern French history, a requirement for the Master's degree with Professor Binion, which was consequential for me, as he taught me to be objective in writing history. Professor Binion was a demanding and outstanding teacher.

  11. Invited commentary: the testimony of Dr. Snow.

    Science.gov (United States)

    Vandenbroucke, J P

    2000-07-01

    This paper presents a commentary on the testimony delivered by Dr. John Snow before the British Parliamentary Committee in 1855. It is noted that in Snow's testimony was highlighted his extremely strong belief in germ theory and contagion and his consequent contempt for anything close to the rivaling theory that miasmatic emanations cause disease. Snow's unreasonableness may have been because he already held his germ theory and drinking water convictions before he made his observations. In addition, based on his published books it has become apparent that even his data analysis was guided by such preconceptions. Although Snow's opinion on germ theory created contemporaries, it is noted however, that Snow did not truly sway contemporary opinion, and his theories were not agreed as a complete breakthrough in the way that they are often presented as being in epidemiological textbooks. Overall, the fundamental problem with the miasma and contagion theories at the time was that both failed to answer certain questions, including transmission of diseases, development of diseases, and the issue of temporary carriers of causative germs.

  12. Results from DR and Instrumentation Test Facilities

    CERN Document Server

    Urakawa, Junji

    2005-01-01

    The KEK Accelerator Test Facility (ATF) is a 1.3GeV storage ring capable of producing ultra-low emittance electron beams and has a beam extraction line for ILC R&D. The ATF has proven to be an ideal place for researches with small, stable beams. 2x1010 single bunch and low current 20 bunch-train with 2.8nsec bunch spacing have been extracted to develop Nano-Cavity BPM’s, FONT, Nano Beam Orbit handling (FEATHER), Optical Diffraction Radiation (ODR) monitor, a precision multi-bunch laser-based beam profile monitor and polarized positron beam generation via backward-Compton scattering by the international collaboration. A set of three cavity BPM's is installed in the ATF extraction line on a set of extremely stiff supports. The KEK group installed another set of three BPM's, with their own support mechanism. The full set of 6 will prove extremely useful. In the DR (Damping Ring), we are researching the fast ion instability, micro-wave instability with four sets of damping wiggler and developing pul...

  13. Galactic rotation in Gaia DR1

    CERN Document Server

    Bovy, Jo

    2016-01-01

    The spatial variations of the velocity field of local stars provide direct evidence of Galactic differential rotation. The local divergence, shear, and vorticity of the velocity field---the traditional Oort constants---can be measured based purely on astrometric measurements and in particular depend linearly on proper motion and parallax. I use data for 304,267 main-sequence stars from the Gaia DR1 Tycho-Gaia Astrometric Solution to perform a local, precise measurement of the Oort constants at a typical heliocentric distance of 230 pc. The pattern of proper motions for these stars clearly displays the expected effects from differential rotation. I measure the Oort constants to be: A = 15.3+/-0.4+/- 0.5 (syst.) km/s/kpc, B = -11.9+/-0.4 km/s/kpc, C = -3.2+/-0.4 km/s/kpc and K = -3.3+/-0.6 km/s/kpc, where the systematic uncertainty in A is due to its uncertain correction for the asymmetric drift. These measurements imply local values for the rotational frequency of \\Omega_0 = 27.1+/-0.5+/- 0.5 (syst.) km/s/kpc,...

  14. Dr. Otto "Tiger" Freer: inventor and innovator.

    Science.gov (United States)

    Chittiboina, Prashant; Connor, David E; Nanda, Anil

    2012-08-01

    Every neurosurgeon develops his or her own standard approach to common intracranial pathologies in terms of the order in which different stages are performed and which instruments are used to perform individual tasks. The majority of the basic steps in performing a craniotomy are learned through repetition and practice during residency training. Significant amounts of energy are devoted to mastering technical skills and developing an operative rhythm. What often receives little attention is the historical origin of the instruments that make the work possible. The Freer elevator represents a particularly interesting example. To people unfamiliar with the accomplishments of turn-of-the-century laryngologist Otto "Tiger" Freer, it can be assumed that the name of the instrument in one's hand is simply named for what it can do, that is, to "free" the nasal mucosa from the bony and cartilaginous septum during the transsphenoidal approach. The technique this master surgeon spent his life and career perfecting is now repeated almost daily by skull base neurosurgeons approaching pathologies from the inferior frontal lobe to the foramen magnum. In reviewing his life and work, the authors of this paper discovered an interesting creative process that led to the design of the eponymous instrument. Additionally, they discovered important advances toward the development of the transnasal approach and in our understanding of the anterior skull base. They present a historical perspective on the life and accomplishments of Dr. Freer and the ubiquitous surgical instrument that he invented and popularized.

  15. An interview with Dr Diane Austin

    Directory of Open Access Journals (Sweden)

    Patricia Preston-Roberts

    2011-03-01

    Full Text Available For many years Dr Diane Austin has been developing a very special use of the voice in her practice as a music psychotherapist. The transformational aspects of this approach have been witnessed by colleagues who have heard Diane present at conferences or have read of her work in various publications. There are now further opportunities for colleagues to find out more about her work by reading her recent book or participating in her trainings. On behalf of the editors of the series of interviews for Voices I am delighted to be able to introduce this interview with Diane by one of her colleagues Patricia Preston-Roberts. There is also a linked audio example. In the interview Diane explains how her approach evolved and she identifies some of the key features of the work. She provides some links to the theories underpinning her practice and talks very openly about some issues of countertransference that arise as part of this very powerful and profound way of working. Throughout the interview we are aware how all aspects of the voice have an enormous influence on the development of a warm and trusting therapeutic relationship. From the moment a client enters Diane's consulting room it is clear that her deep and empathic listening ability enables her to make connections to every vocal nuance, whether spoken or sung. As she points out "the whole session" can be viewed "as an improvisation."

  16. Study of HLA-DR synthesis in cultured human keratinocytes.

    Science.gov (United States)

    Wikner, N E; Huff, J C; Norris, D A; Boyce, S T; Cary, M; Kissinger, M; Weston, W L

    1986-11-01

    Within the normal human epidermis only Langerhans and indeterminate cells express HLA-DR. Human keratinocytes (HK), however, may also express HLA-DR in certain disease states characterized by mononuclear cell infiltrates. Previous studies have shown that HK synthesize HLA-DR in response to stimulation by interferon gamma (INF-gamma). The purposes of this study were to define conditions under which cultured HK might express HLA-DR and to compare the HLA-DR synthesis of HK with that of monocytes. HLA-DR expression by HK as determined by indirect immunofluorescence of HK cultures was absent under standard low calcium conditions and remained absent with the addition of calcium, serum, mitogens, and supernatants from Pam-212 cells containing epidermal thymocyte-activating factor. HLA-DR expression in HK was induced by cocultivation with concanavalin A-stimulated peripheral blood mononuclear cells (PBMC), but not unstimulated PBMC. This effect was time-dependent and directly related to the number of PBMC. HLA-DR expression was also induced in a time- and dose-dependent manner by addition of supernatant from stimulated PBMC (SS) or by addition of recombinant INF-gamma but not by addition of interleukin (IL)-1 or IL-2. Induction by either SS or INF-gamma was blocked by an antiserum to INF-gamma. As determined by a semiquantitative immunoprecipitation technique, HLA-DR synthesis by HK was directly related to INF-gamma concentration. The pattern of HLA-DR peptides produced by HK was similar to that of monocytes, but the relative quantity synthesized was far less than that of monocytes.

  17. Induction of Tumor Cell Apoptosis via Fas/DR5

    Institute of Scientific and Technical Information of China (English)

    Wenzhu Li; Shengyu Wang; Caixia Chen; Guohong Zhuang

    2006-01-01

    The apoptosis inducing effects on tumor cell lines MGC803, BEL7402 and HL60 by Fas ligand and anti-human DR5 monoclonal antibodies (anti-DR5 mAb) and the underlying mechanism was studied, Fas/DR5 mRNA was detected by RT-PCR. Cytotoxicity exerted by FasL/anti-DR5 mAb on tumor cell lines was measured by MTT assay and the induced apoptosis was determined by agarose gel electrophoresis. Flow cytometry was employed to analyze the mode of cell death. The mRNA expression of DR5 in MGC803 and BEL7402 cells after giving anti-DR5 mAb was up-regulated compared with control group, while it was down-regulated in HL60 cells in the same condition.The mRNA expression of Fas in HL60 was higher after giving FasL compared with control group, while it was lower in MGC803 and BEL7402. MGC803 and BEL7402 were sensitive to anti-DR5 mAb but partially to FasL,and HL60 was sensitive to FasL but less sensitive to anti-DR5 mAb. Apoptosis induced by Fas ligand and anti-DR5 mAb vary among tumor cell lines. The underlying mechanism may be relevant to Fas/DR5 mRNA expression,which was presented as the release of caspase-8 and Bcl-2.

  18. Dr. Steve Thompson, Chief Executive, The Royal Society of New Zealand

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    L. to r.: Dr Austin Ball, Deputy Technical Coordinator, CMS experiment; Dr Roland Horisberger, Paul Scherrer Institute and CERN, CMS experiment; Dr Steve Thompson, Chief Executive, The Royal Society of New Zealand; Dr Michel Della Negra, Spokesman, CMS experiment and Dr Alick Macpherson, Paul Scherrer Institute and CERN, CMS experiment, in the CMS Silicon Tracker assembly hall.

  19. Enrico Fermi Awards Ceremony for Dr. Mildred S. Dresselhaus and Dr. Burton Richter, May 2012 (Presentations, including remarks by Energy Secretary, Dr. Steven Chu)

    Energy Technology Data Exchange (ETDEWEB)

    Chu, Steven (U.S. Energy Secretary)

    2012-05-07

    The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On May 7, 2012 it was conferred upon two exceptional scientists: Dr. Mildred Dresselhaus, 'for her scientific leadership, her major contributions to science and energy policy, her selfless work in science education and the advancement of diversity in the scientific workplace, and her highly original and impactful research,' and Dr. Burton Richter, 'for the breadth of his influence in the multiple disciplines of accelerator physics and particle physics, his profound scientific discoveries, his visionary leadership as SLAC Director, his leadership of science, and his notable contributions in energy and public policy.' Dr. John Holder, Director of the White House Office of Science and Technology Policy, opened the ceremony, and Dr. Bill Brinkman, Director of DOE's Office of Science introduced the main speaker, Dr. Steven Chu, U.S. Energy Secretary.

  20. War, plague and exploitation in DR Congo

    Directory of Open Access Journals (Sweden)

    Dimčevska Antoaneta K.

    2007-01-01

    Full Text Available Late in autumn 2006 one of the headlines in world media was the first democratic elections in DR Congo. They took place after 30 years of Mobutu Sese Seko’s dictatorship and bloody civil wars in the period 1996-2002. These conflicts, which took approximately 4 million human lives, are called "The First African World War". Elections were held but they did not guarantee the end of trouble for the divided and tormented people in the northeast of Congo, the real scene of bloodshed. The area is still turbulent because it abounds in mineral wealth - gold, diamonds and raw materials for nuclear technology. For a whole decade, unscrupulous actors of the African crisis were fighting there, for illegal profits (achievable in the chaos of bloodshed rather than for democracy, defense of tribal interests, security, etc. as they claimed. In the mines of Eastern Congo unprecedented exploitation of people is still going on, especially of children, victims of conflicts, who suffer in great numbers from violence, starvation and diseases. These slaves of the crisis make local "warlords" and their mentors rich. The looting of the mines has stabilized the crisis because it makes possible enormous accumulation of wealth among armed decision-makers - which also includes availability of countless slaves-miners who have lost everything except their bare lives. Eastern Congo is, however, one of world’s three old focuses of plague; wild exploitation of ores in the area of this endemic disease has activated a sleepy focus and added pneumonic plague to the burdens suffered by the population of the rich but ill-fated region. This was to be expected because endemic plague in the gold-bearing evil circumstances impedes safe mining - and this will be the crucial challenge in the future of Congo. This article is an anthropological outline of the area where gold, plague, weapons and incomparable suffering of people merge together just because of cynic greed producing abuse

  1. Dr. George Koob: "Alcohol Use Disorders Are a Major Problem..."

    Science.gov (United States)

    ... please turn JavaScript on. Feature: Rethinking Drinking Dr. George Koob: "Alcohol use disorders are a major problem …" Past Issues / Spring 2014 Table of Contents George Koob, Ph.D., is Director of the NIH's ...

  2. Dr. Omalu Talks Childhood, Concussions, and CTE | Poster

    Science.gov (United States)

    Dr. Bennet Omalu, the famed forensic pathologist who discovered Chronic Traumatic Encephalopathy (CTE), recently spoke at NCI at Frederick about his upbringing as well as the trials he faced while working to educate the NFL about CTE.

  3. Three Typical Dermatological Cases Treated by Dr. Li Yueping

    Institute of Scientific and Technical Information of China (English)

    Xie Shaoqiong

    2005-01-01

    @@ Dr. Li Yueping has been engaged in dermatological clinic for more than 40 years, accumulating rich experience in treating dermatological diseases. The following is three typical cases she gave successful treatment.

  4. Dr Abraham Pais, 82, physicist and science historian dies

    CERN Multimedia

    Glanz, J

    2000-01-01

    Obituary of Dr. Pais who died of heart failure in Copenhagen. He helped build the conceptual foundations of particle physics and then became a science historian, writing a critically acclaimed biography of Einstein (1 pg).

  5. Grantee Spotlight: Dr. Kolawole Okuyemi - Improving Cervical Cancer Screening Attitudes

    Science.gov (United States)

    Dr. Kolawole Okuyumi is studying cervical cancer screening attitudes and behaviors of African immigrants and refugees in Minnesota, and introducing “cancer” and “cervix” to their everyday vocabulary.

  6. Adipose tissue resistin gene expression in DIO and DR rats

    Institute of Scientific and Technical Information of China (English)

    Yuanyuan Zhao; Yuhui Ni; Xirong Guo; Haixia Gong; Xia Chi; Ronghua Chen

    2006-01-01

    Objective: To investigate the expression of resistin gene in diet-induced obesity (DIO) and diet resistance (DR)rats. Methods: DIO and DR models were prepared with male SD rats after 6 weeks feeding by a diet of relatively high fat, sucrose, and caloric content (HE diet). Body-weight, fat mass, and the concentration of serum insulin were measured, and the expression of resistin and Peroxisome proliferator-activated receptory-γ(PPAR-γ) gene in whit adipose tissue (WAT) was also detected by RT-PCR. Results: ①Body weight, fat mass and the concentration of serum insulin were significantly increased in DIO rats and decreased in DR rats. ② The expression of resistin and PPARγ gene was upregulated in DIO group and supressed in DR group, but the expression of resistin was not detectable in all samples within three groups. Conclusion: Resistin may serve as a link between obesity and insulin resistance, but the individual difference is enormous.

  7. Glaucoma: Eye-to-Eye with Dr. Rachel Bishop

    Science.gov (United States)

    ... of this page please turn JavaScript on. Feature: Glaucoma Eye-to-Eye with Dr. Rachel Bishop Past ... nerves are pale and cupped—signs of advanced glaucoma. Yet the patient wasn't aware of any ...

  8. Den som dræber spændingen

    DEFF Research Database (Denmark)

    Agger, Gunhild

    2011-01-01

    TV 2's stort lancerede krimithriller ’Den som dræber’ er klicheernes holdeplads. Det gør det til en kedelig oplevelse at tænde for TV 2 søndag aften kl. 20. TV 2 har udfordret DR på sendetidspunktet, men har for lidt at byde på. Der er tale om ren rutine. Ingen af genrens centrale elementer glimrer...

  9. A periodontal case report by Dr. S.L. Clemens.

    Science.gov (United States)

    Maloney, W J

    2010-07-01

    Mark Twain provides a humorous and insightful look into the origins of periodontal therapy and anesthesia in "Happy Memories of the Dental Chair". The main character of this story is Dr. John Riggs, the father of periodontics. Dr. Horace Wells, a pioneer in the field of anesthesia, also appears in the story. Twain presents his autobiographical experiences with dentistry in his literary work in a form that can be seen to be similar to a case report in a professional dental journal.

  10. Dr. David Syz, State Secretary for Economic Affairs, Switzerland

    CERN Document Server

    Maximilien Brice

    2003-01-01

    Dr. David Syz, State Secretary for Economic Affairs, Switzerland is seen here (seventh from right) visiting the assembly hall for the ATLAS experiment during his recent visit to CERN. To his right is Dr. Peter Jenni (blue shirt), spokesperson for the ATLAS Collaboration. The horizontal metal cylinder behind the group is one of the eight vacuum vessels for the superconducting coils of the ATLAS barrel toroid magnet system.

  11. The research contributions of Dr. Paul Van Deusen

    Science.gov (United States)

    Thomas B. Lynch; Francis A. Roesch; John Paul McTague; Jeffrey H. Gove; Gregory A. Reams; Aaron R. Weiskittel

    2015-01-01

    Dr. Paul Van Deusen’s recent passing concluded a rich 30+-year research career dedicated to development and implementation of quantitative methods for forestry and natural resources. Since the early part of his career as a biometrician with the USDA Forest Service Southern Research Station in the 1980s-1990s and continuing with his later employment at NCASI, Dr. Van...

  12. Portrait of Dr. Von Braun with Walt Disney, 1954.

    Science.gov (United States)

    1954-01-01

    Marshall Center Director Dr. Wernher Von Braun is pictured with Walt Disney during a visit to the Marshall Space Flight Center in 1954. In the 1950s, Dr. Von Braun while working in California on the Saturn project, also worked with Disney studios as a technical director in making three films about Space Exploration for television. Disney's tour of Marshall in 1965 was Von Braun's hope for a renewed public interest in the future of the Space Program at NASA.

  13. Dr. Peter Emil Becker and the Third Reich.

    Science.gov (United States)

    Hill, Frank

    2013-08-01

    In 1985 the physician after whom Becker Muscular Dystrophy is named, German neurologist Dr. Peter Emil Becker (1908-2000), published an autobiographical article in the American Journal of Medical Genetics in which he disavowed any association with the Nazi Party. A closer look at the evidence, however, suggests otherwise. Review of war records and related sources raise concern for Dr. Becker's affiliation with the Nazi Party and his contributions to its ideology.

  14. DR-current intensity variations during substorm development

    Science.gov (United States)

    Zaitseva, S. A.; Drobinina, T. A.; Pudovkin, M. I.

    2003-04-01

    According to the concept dominated by the last time, the intensification of the DR-current takes place during the polar substorm development. In the recent papers Iyemori and Rao claim that geomagnetic storms and substorms are independent processes, and SYM-index (essentially the same as Dst-index) tends to decay after the onset of substorms. In this paper we tried to clear up the cause of this contradiction by studying the connection of ring current development with polar substorms basing on the new data: ASY-, SYM-indices describing asymmetric and symmetric parts of DR-current correspondingly and AL-index as a measure of polar disturbances. It is shown that the hourly-mean SYM- and ASY-indices correlate with AL-index (r=0.63 and 0.69 correspondingly), and the connection between these values becomes worse for strong storms. Besides, at the substorm expansive phase onset, the energy can put mainly to the asymmetric part rather than into symmetric part of DR-current. Empirical Q-index based on solar wind parameters describes the energy input into DR-current; Q correlates rather well with SYM, ASY and AL-indices. Thus the intensifications of polar disturbances and DR-current take place simultaneously and have the same source.At the same time, the proportion in which the solar wind energy is distributed between the DR-current, polar ionosphere and magnetotail depends on the Dst variation phase.

  15. [Sexuality education on the Internet : From Dr. Sommer to Dr. Google].

    Science.gov (United States)

    Döring, Nicola

    2017-07-24

    Female and male adolescents in Germany are increasingly using the Internet to find information about sexuality and sexual health. This review paper summarizes what we know about the status quo of online sexuality education in Germany.Based on a systematic literature review including 40 papers from international, peer-reviewed journals spanning 2010-2017, this paper first describes different aspects of the sexuality-related online search behavior of adolescents: its prevalence, predictors, topics and contexts. One main finding is the fact that adolescents use a computer or smartphone to type their sexuality-related questions into the search engine Google or the search engine of the video platform YouTube.Based on 54 online searches, this paper subsequently presents the kind of sexuality-related online content adolescents find if they ask "Dr. Google" for sexual advice; a collection of 1236 authentic sexuality-related questions of adolescents was used for this analysis. It turned out that online sexuality education offered by leading professional organizations like the BZgA ("Bundeszentrale für gesundheitliche Aufklärung") or pro familia was nearly invisible, while numerous other providers of online sex education consistently appeared in the top Google search results. Among them were the "Dr. Sommer" team of the youth magazine Bravo; online healthcare and advice portals; online forums; the online encyclopedia Wikipedia and, above all, sex education channels on YouTube. In this paper, the latter are presented in more detail for the first time.The third part of the paper addresses the quality of online sexual education over four main areas of quality evaluation. The presentation of the status quo ends with some recommendations both for future research and for sexuality education in practice.

  16. Remaining Sites Verification Package for 132-DR-1, 1608-DR Effluent Pumping Station, Waste Site Reclassification Form 2005-035

    Energy Technology Data Exchange (ETDEWEB)

    R. A. Carlson

    2005-09-22

    Radiological characterization, decommissioning and demolition of the 132-DR-1 site, 1608-DR Effluent Pumping Station was performed in 1987. The current site conditions achieve the remedial action objectives and the corresponding remedial action goals established in the Remaining Sites ROD. Residual concentrations support future land uses that can be represented by a rural-residential scenario and pose no threat to groundwater or the Columbia River based on RESRAD modeling.

  17. Volume celebrating the 60th birthday of Professor Dr. Franz Fie; Professor Dr. Franz Fiedler zum 60. Geburtstag

    Energy Technology Data Exchange (ETDEWEB)

    Beheng, K.D. [ed.

    1998-01-01

    This report was compiled in honor of Professor Dr. Franz Fiedler on the occasion of his 60th birthday on 7 January 1998. Its contributions deal with mesoscale modelling, the propagation of air pollutants, measurements of precipitation using radar, and prediction models. (orig./KW) [Deutsch] Dieser Bericht wurde aus Anlass des 60. Geburtstags von Herrn Prof. Dr. Franz Fiedler am 7. Januar 1998 zusammengestellt. Die Beitraege behandeln mesoskalige Modellierung, Ausbreitung von Luftschadstoffen, Niederschlagsmessung mit Radar und Vorhersagemodelle. (orig.)

  18. HLA DR4w4-binding motifs illustrate the biochemical basis of degeneracy and specificity in peptide-DR interactions.

    Science.gov (United States)

    Sette, A; Sidney, J; Oseroff, C; del Guercio, M F; Southwood, S; Arrhenius, T; Powell, M F; Colón, S M; Gaeta, F C; Grey, H M

    1993-09-15

    In the present study, we describe the definition of a DRB1*0401 (DR4w4)-specific motif. The strategy used entailed a three-step process: 1) screening a large set of unrelated peptide ligands to identify good MHC binders; 2) truncation analysis of several DR4w4 binding peptides of high affinity to identify the crucial core-binding regions; 3) the use of single amino acid substitutions of the DR4w4-binding peptide hemagglutinin (HA) 307-319 to elucidate the specific residues crucial for binding. The DR4w4 motif is characterized by the presence of a hydrophobic or aromatic (F, W, Y, L, I, V, M) anchor residue in position 1, and a second hydroxyl (S, T) or aliphatic (L, I, V, or M) anchor residue in position 6. Furthermore, positive charges (R, K) are not allowed in positions 4, 7, and 9, and negative charges (D, E) are not allowed in position 9. This motif was present in 92% of good (IC50 45 microM) binders, indicating that the presence of the motif is necessary, but not sufficient for good DR4w4 binding capacity. The results of the present study are discussed in relation to previous work defining binding motifs and rules for other DR alleles, illustrating how different DR alleles bind variations on a similar structural theme. Finally, using two different peptide ligands [tetanus toxoid 830-843 and HA 307-319] as model systems, it is demonstrated how the fine allelic specificity of the DR binders can be predictably modulated by introducing subtle changes in the primary amino acid sequence.

  19. Overall properties of the Gaia DR1 reference frame

    Science.gov (United States)

    Liu, N.; Zhu, Z.; Liu, J.-C.; Ding, C.-Y.

    2017-03-01

    Aims: The first Gaia data release (Gaia DR1) provides 2191 ICRF2 sources with their positions in the auxiliary quasar solution and five astrometric parameters - positions, parallaxes, and proper motions - for stars in common between the Tycho-2 catalogue and Gaia in the joint Tycho-Gaia astrometric solution (TGAS). We aim to analyze the overall properties of Gaia DR1 reference frame. Methods: We compare quasar positions of the auxiliary quasar solution with ICRF2 sources using different samples and evaluate the influence on the Gaia DR1 reference frame owing to the Galactic aberration effect over the J2000.0-J2015.0 period. Then we estimate the global rotation between TGAS with Tycho-2 proper motion systems to investigate the property of the Gaia DR1 reference frame. Finally, the Galactic kinematics analysis using the K-M giant proper motions is performed to understand the property of Gaia DR1 reference frame. Results: The positional comparison between the auxiliary quasar solution and ICRF2 shows negligible orientation and validates the declination bias of -0.1mas in Gaia quasar positions with respect to ICRF2. Galactic aberration effect is thought to cause an offset 0.01mas of the Z axis direction of Gaia DR1 reference frame. The global rotation between TGAS and Tycho-2 proper motion systems, obtained by different samples, shows a much smaller value than the claimed value 0.24mas yr-1. For the Galactic kinematics analysis of the TGAS K-M giants, we find possible non-zero Galactic rotation components beyond the classical Oort constants: the rigid part ωYG = -0.38±0.15mas yr-1 and the differential part ω^primeYG = -0.29±0.19mas yr-1 around the YG axis of Galactic coordinates, which indicates possible residual rotation in Gaia DR1 reference frame or problems in the current Galactic kinematical model. Conclusions: The Gaia DR1 reference frame is well aligned to ICRF2, and the possible influence of the Galactic aberration effect should be taken into consideration

  20. HLA-DR-positive cells in large plaque (atrophic) parapsoriasis.

    Science.gov (United States)

    McMillan, E M; Wasik, R; Everett, M A

    1981-10-01

    The development of a monoclonal antibody directed against HLA DR (Ia-like) antigens of B cells and monocytes but not against normal peripheral human T cells suggested that this antibody might be used as a marker of B cells and monocytes in tissue sections. The T cell nature of large plaque (atrophic) parapsoriasis has recently been demonstrated by the immunoperoxidase technic. Immunoperoxidase examination of serial sections of tissues from two cases of large plaque parapsoriasis with one T cell antiserum, two monoclonal T cell antibodies, and one monoclonal reagent directed against HLA DR indicated that T cells in the cutaneous infiltrates were also HLA DR-positive. Evidence is accumulating that HLA DR positivity may be expressed by activated T cells. The findings here therefore suggest that many of the T lymphoid cells in two cases of large plaque (atrophic) parapsoriasis examined were activated in nature, and that HLA DR may not be a specific marker for B cells and monocytes in certain pathologic conditions. Caution should therefore presently be exercised in attempting to use this marker for the specific identification of B cells and monocytes in pathologic specimens, without simultaneous testing for T cell markers.

  1. DR WHO: a workshop for house officer preparation.

    Science.gov (United States)

    Cave, Judith; Wallace, Deirdre; Baillie, Glenda; Klingenberg, Michael; Phillips, Catherine; Oliver, Harriet; Rowles, Katherine; Dunkley, Lisa; Sturrock, Alison; Dacre, Jane

    2007-01-01

    Newly qualified doctors should be competent in advanced life support (ALS) and critical care. The Resuscitation Council has published a course about ALS for undergraduate medical students (the intermediate life support (ILS) course). However, there is no undergraduate-level course on assessing and treating critically ill patients, despite the fact that postgraduate courses on this topic are extremely popular. We have developed a new course called Direct Response Workshop for House Officer Preparation (DR WHO), which teaches both ALS and critical care at an undergraduate level. We taught the Resuscitation Council ILS course to our 2003-4 cohort of final year medical students (n = 350), and the new course (DR WHO) to our 2004-5 cohort (n = 338). Students filled in feedback forms immediately after the courses, and a subset repeated the feedback forms 4 months after they had started work as house officers. Course evaluation: Student and house officer feedback was positive. The DR WHO cohort was more confident in caring for critically ill patients (18/26 (69%) were confident after ILS, and 40/45 (89%) were confident after DR WHO (chi2 = 4.3; df = 1; p = 0.06)). Both cohorts were competent in ALS, each with a mean score of 18.6/20 in a finals level practical examination on this topic. The DR WHO course is popular with the students and practical to run. The course needs to be re-evaluated to determine the long-term competency of graduates.

  2. Statistical Study of 2XMMi-DR3/SDSS-DR8 Cross-correlation Sample

    CERN Document Server

    Yan-Xia, Zhang; Yong-Heng, Zhao; Xue-Bing, Wu; 10.1088/0004-6256/145/2/42

    2013-01-01

    Cross-correlating the XMM-Newton 2XMMi-DR3 catalog with the Sloan Digital Sky Survey (SDSS) Data Release 8, we obtain one of the largest X-ray/optical catalogs and explore the distribution of various classes of X-ray emitters in the multidimensional photometric parameter space. Quasars and galaxies occupy different zones while stars scatter in them. However, X-ray active stars have a certain distributing rule according to spectral types. The earlier the type of stars, the stronger X-ray emitting. X-ray active stars have a similar distribution to most of stars in the g-r versus r-i diagram. Based on the identified samples with SDSS spectral classification, a random forest algorithm for automatic classification is performed. The result shows that the classification accuracy of quasars and galaxies adds up to more than 93.0% while that of X-ray emitting stars only amounts to 45.3%. In other words, it is easy to separate quasars and galaxies, but it is difficult to discriminate X-ray active stars from quasars and...

  3. Professor Bakytzhan Abdiraiym Rector of the L. Gumilov Eurasian National University, Astana, Kazakhstan accompanied by Prof. Kairat Kuterbekov, Dr Bekzat Prmantayeva, Dr Kuralay Maksut with the Director-General, Dr Tadeusz Kurtyka, Adviser for Non-Member States, Mrs Julia Andreeva, Department of Information Technologies and Dr Nikolai Zimine, ATLAS Collaboration, Joint Institute for Nuclear Research, Dubna

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    Professor Bakytzhan Abdiraiym Rector of the L. Gumilov Eurasian National University, Astana, Kazakhstan accompanied by Prof. Kairat Kuterbekov, Dr Bekzat Prmantayeva, Dr Kuralay Maksut with the Director-General, Dr Tadeusz Kurtyka, Adviser for Non-Member States, Mrs Julia Andreeva, Department of Information Technologies and Dr Nikolai Zimine, ATLAS Collaboration, Joint Institute for Nuclear Research, Dubna

  4. Tun Dr. Mahathir’s Leadership Communication: The Confucian Perspective

    Directory of Open Access Journals (Sweden)

    Cheah Joyce Lynn-Sze

    2017-01-01

    Full Text Available Previous studies have provided valuable insights into the impact of culture on the concept of leadership communication. However, only a few studies that focused on exploring and understanding the values of Confucianism and its impact on the Chinese culture, especially in Malaysia. Thus, this study is among the first study to examine the leadership communication from the perspective of Confucianism towards the leadership of Dr. Mahathir from the perspective of the Chinese community in Malaysia. This study aims to assess the role of Confucian values in Dr. Mahathir’s leadership communication. This study interviewed 15 Chinese leaders. The findings reveal that three main Confucian values are relevant to Dr. Mahathir’s leadership communication. The Confucian values are Zhi (wisdom, Xin (trust and Xiao (filial piety. This study provides a new perspective on leadership communication from the context of cultural diversity in Malaysia which emphasizes on Confucian values.

  5. Dr. Xie Haizhou's Experience in Treating Senile Dementia

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ Dr. Xie Haizhou, a renowned TCM physician, comes from an aristocratic TCM family, and is now a distinguished research fellow in China Academy of Chinese Medical Sciences. Having been engaged in TCM clinical practice, scientific research and teaching for more than 60 years, Dr. Xie has obtained rich experience in the treatment of obstinate and miscellaneous diseases, especially diseases of the brain and spinal cord. The authors have been fortunate enough to study under him and benefited a lot from his experience. The following is a brief introduction to his experience in the treatment of senile dementia.

  6. Study of photoluminescence properties of thin films DR1

    Energy Technology Data Exchange (ETDEWEB)

    Herman,, E-mail: herman@fi.itb.ac.id; Ulya, Naily, E-mail: naily.ulya@gmail.com [Physics of Magnetism and Photonics Group, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung (Indonesia)

    2015-09-30

    Fabrication of thin films DR1 have been carried out by the EFA-PDF (Electric Field-Assisted Physical Vapor Deposition) method to obtain films with parallel dipole arrangement. Molecular deposition process is performed by applying an electric field that is placed between the substrate ITO (Indium Tin Oxide) and copper mesh. The resulting films were characterized by using a spectrofluorometer. Analysis of the emission spectrum, indicate that DR1 molecules in the film oriented perpendicular to the substrate and arranged in parallel order (H-aggregate). As an effect, the peak of the emission spectrum appears stronger along with the increase of electric field strength.

  7. Dr Jacob van der Land, marine biologist extraordinary

    OpenAIRE

    Bruggen, van, A.

    2001-01-01

    This contribution is an attempt to sketch the life and works of Dr Jacob van der Land, curator of worms and chief marine biologist of the National Museum of Natural History, on the occasion of his official retirement. Born in 1935, Jacob van der Land read biology at Leiden University (1958-1964), where he obtained his Ph.D. in 1970 on a treatise on the Priapulida under the supervision of Prof. Dr L.D. Brongersma. In 1964 he was appointed curator of worms in the museum. Later on he took over l...

  8. STATISTICAL STUDY OF 2XMMi-DR3/SDSS-DR8 CROSS-CORRELATION SAMPLE

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Yanxia; Zhou Xinlin; Zhao Yongheng [Key Laboratory of Optical Astronomy, National Astronomical Observatories, Chinese Academy of Sciences, 20A Datun Road, Chaoyang District, 100012 Beijing (China); Wu Xuebing, E-mail: zyx@bao.ac.cn [Department of Astronomy, Peking University, 100871 Beijing (China)

    2013-02-01

    Cross-correlating the XMM-Newton 2XMMi-DR3 catalog with the Sloan Digital Sky Survey (SDSS) Data Release 8, we obtain one of the largest X-ray/optical catalogs and explore the distribution of various classes of X-ray emitters in the multidimensional photometric parameter space. Quasars and galaxies occupy different zones while stars scatter in them. However, X-ray active stars have a certain distributing rule according to spectral types. The earlier the type of stars, the stronger its X-ray emitting. X-ray active stars have a similar distribution to most stars in the g - r versus r - i diagram. Based on the identified samples with SDSS spectral classification, a random forest algorithm for automatic classification is performed. The result shows that the classification accuracy of quasars and galaxies adds up to more than 93.0% while that of X-ray emitting stars only amounts to 45.3%. In other words, it is easy to separate quasars and galaxies, but it is difficult to discriminate X-ray active stars from quasars and galaxies. If we want to improve the accuracy of automatic classification, it is necessary to increase the number of X-ray emitting stars, since the majority of X-ray emitting sources are quasars and galaxies. The results obtained here will be used for the optical spectral survey performed by the Large sky Area Multi-Object fiber Spectroscopic Telescope (LAMOST, also named the Guo Shou Jing Telescope), which is a Chinese national scientific research facility operated by the National Astronomical Observatories, Chinese Academy of Sciences.

  9. Dr. Long Wenjun's Experience in Auriculo-Acupuncture

    Institute of Scientific and Technical Information of China (English)

    Tian Yongping; Hou Chunying

    2007-01-01

    @@ Having been engaged in TCM practice for more than 40 years, Dr. Long Wenjun from Gansu College of Traditional Chinese Medicine is very good at treating acute infectious diseases, acute painful diseases and certain obstinate diseases with auriculo-acupuncture. Following is an introduction to his experience with some sample cases.

  10. Keeping the Dream Alive. Dr. Martin Luther King, Jr.

    Science.gov (United States)

    Cassells, Linda; And Others

    1993-01-01

    Presents activities for teaching elementary students about Dr. Martin Luther King's life, the civil rights movement, and King's accomplishments. Suggestions include shoebox dioramas, acronym games, oral histories, multicultural awareness activities, pledge cards, community service projects, special commemorative ceremonies, and a book of dreams.…

  11. Dr.Xuan Guowei's Experience in Treating Dermatosis

    Institute of Scientific and Technical Information of China (English)

    刘爱民

    2004-01-01

    @@ Dr. Xuan Guowei has been engaged in medical practice, teaching and scientific research on dermatosis for nearly 40 years, and is famous for his meticulous scholarship and outstanding art of healing. The following are some examples of his unique academic ideas and creative clinical practice.

  12. HLA-DR expression and disease activity in ulcerative colitis

    DEFF Research Database (Denmark)

    Poulsen, L O; Elling, P; Sørensen, Flemming Brandt

    1986-01-01

    In 12 patients with active ulcerative colitis (UC) the rectal epithelial cells were analyzed for HLA-DR antigens by an immunohistochemical technique. The clinical, rectoscopic, and histologic stages were also determined. The investigations were carried out at the beginning of the study and 2 weeks...

  13. Dr.Zhu Hongming's Experience in Treating Chronic Gastritis

    Institute of Scientific and Technical Information of China (English)

    朱传伟

    2004-01-01

    @@ Dr. Zhu Hongming has engaged in TCM internal medicine for more than 40 years and accumulated rich clinical experience, especially in the treatment of diseases of the spleen and stomach. The following is a brief introduction to his experience in TCM differential treatment of chronic gastritis.

  14. Obituary Dr A. W. Kloos (1880—1952)

    NARCIS (Netherlands)

    Ooststroom, van S.J.

    1952-01-01

    At the end of the previous number of “Blumea” could just be inserted the death notice of one of the honorary collaborators of the Rijksherbarium, Dr Ir A. W. Kloos, who passed away in his home at Dordrecht on June 3rd, 1952. A more detailed obituary may follow here. Abraham Willem Kloos was born at

  15. Shepard Award Winners, Part 1: Dr. Stephen Thacker

    Centers for Disease Control (CDC) Podcasts

    2009-07-22

    This podcast highlights the accomplishments of Dr. Stephen Thacker, recipient of the prestigious 2009 CDC Charles C. Shepard Award.  Created: 7/22/2009 by Centers for Disease Control and Prevention (CDC).   Date Released: 7/22/2009.

  16. Shepard Award Winners, Part 3: Dr. Larissa Roux

    Centers for Disease Control (CDC) Podcasts

    2009-09-22

    This podcast highlights the accomplishments of Dr. Larissa Roux, recipient of the prestigious 2009 CDC Charles C. Shepard Award.  Created: 9/22/2009 by Centers for Disease Control and Prevention (CDC).   Date Released: 9/22/2009.

  17. Shepard Award Winners, Part 2: Dr. Tracie Williams

    Centers for Disease Control (CDC) Podcasts

    2009-07-29

    This podcast highlights the accomplishments of Dr. Tracie Williams, recipient of the prestigious 2009 CDC Charles C. Shepard Award.  Created: 7/29/2009 by Centers for Disease Control and Prevention (CDC).   Date Released: 7/29/2009.

  18. Dr Jacob van der Land, marine biologist extraordinary

    NARCIS (Netherlands)

    Bruggen, van A.C.

    2001-01-01

    This contribution is an attempt to sketch the life and works of Dr Jacob van der Land, curator of worms and chief marine biologist of the National Museum of Natural History, on the occasion of his official retirement. Born in 1935, Jacob van der Land read biology at Leiden University (1958-1964), wh

  19. Professor Oberth and Dr. von Braun at ARS Banquet

    Science.gov (United States)

    1961-01-01

    Dr. Wernher von Braun holds the coveted Hermarn Oberth award presented to him by Professor Oberth during the banquet hosted by the Alabama Section of the American Rocket Society (ARS), on October 19, 1961. The Oberth award was given for outstanding technical contributions to the field of astronautics or for the promotion and advancement of astronautical sciences.

  20. Dr. Yi Juqing's Experience in Treating Female Infertility

    Institute of Scientific and Technical Information of China (English)

    Meng Jimin

    2006-01-01

    @@ With rich experience accumulated in medical practice for 40 years, Dr. Yi Juqing (易菊清), a chief physician, is good at treating various kinds of refractory diseases. The following is an introduction of his experience in treating female infertility.

  1. Oxygen and Metastasis: A Conversation with Dr. Nick Restifo

    Science.gov (United States)

    Dr. Nick Restifo, a senior investigator in NCI’s Center for Cancer Research, discusses his recently published study finding that Oxygen, a molecule necessary for life, paradoxically aids cancer metastasis to the lung by impairing cancer-killing immune cells.

  2. Dr. Martin Luther King: A Unit for Primary Grades.

    Science.gov (United States)

    Sweet, Kelli

    1986-01-01

    Presents a unit consisting of 4 lessons which focus on Dr. Martin Luther King, Jr.'s childhood, his adult life and family, his civil rights work, and the national holiday which commemorates his birthday. Each lesson features specific objectives, learning activities, and instructional guidelines for the teacher. (TRS)

  3. The SDSS DR6 Luminosity Functions of Galaxies

    CERN Document Server

    Montero-Dorta, Antonio D

    2008-01-01

    We present number counts, luminosity functions (LFs) and luminosity densities of galaxies obtained using the Sloan Digital Sky Survey Sixth Data Release in all SDSS photometric bands. Thanks to the SDSS DR6, galaxy statistics have increased by a factor of ~9 in the u-band and by a factor of ~4-5 in the rest of the SDSS bands with respect to the previous work of Blanton et al. (2003b). In addition, we have achieved a high redshift completeness in our galaxy samples. Firstly, by making use of the survey masks, provided by the NYU-VAGC DR6, we have been able to define an area on the sky of high angular redshift completeness. Secondly, we guarantee that brightness-dependent redshift incompleteness is small within the magnitude ranges that define our galaxy samples. With these advances, we have estimated very accurate SDSS DR6 LFs in both the bright and the faint end. In the {0.1}^r-band, our SDSS DR6 luminosity function is well fitted by a Schechter LF with parameters Phi_{*}=0.90 +/- 0.07$, M_{*}-5log_{10}h=-20....

  4. Dr. Feng Xinghua's Experience in Treating Ankylosing Spondylitis

    Institute of Scientific and Technical Information of China (English)

    Liu Hongxiao

    2006-01-01

    @@ Ankylosing spondylitis (AS) is a rheumatic disease mainly involving the axial joints, characterized by sacro-iliilis and rigid spine. Dr. Feng Xinghua from Guang'anmen Hospital affiliated to China Academy of Chinese Medical Sciences has been engaged in the clinical research and treatment of arthralgia syndrome for more than 30 years. His experience is summarized as follows.

  5. Another Use for Dr. Seuss: Reading for Social Skills

    Science.gov (United States)

    Wolf, Janice J.; Baker, Pamela Hudson

    2012-01-01

    Time is limited. Teachers often struggle to address the diverse needs of learners in their classrooms, especially when faced with academic and social skills concerns. Finding effective ways to teach social skills in the context of academic instruction makes sense. Books by Dr. Seuss provide a variety of high-interest stories that can be used to…

  6. Celebrate the legacy of Dr. Martin Luther King Jr.

    OpenAIRE

    Lazenby, Jenna

    2006-01-01

    In celebration of the life and legacy of Dr. Martin Luther King, Jr., Virginia Tech will host a variety of educational and cultural programs and community service events Jan. 14-19, 2007. All events are free and open to the public.

  7. HLA-DR expression and disease activity in ulcerative colitis

    DEFF Research Database (Denmark)

    Poulsen, L O; Elling, P; Sørensen, Flemming Brandt

    1986-01-01

    In 12 patients with active ulcerative colitis (UC) the rectal epithelial cells were analyzed for HLA-DR antigens by an immunohistochemical technique. The clinical, rectoscopic, and histologic stages were also determined. The investigations were carried out at the beginning of the study and 2 weeks...

  8. Dr. Vernon W. Hughes, 81, authority on the subatomic

    CERN Multimedia

    Lavietes, S

    2002-01-01

    "Dr. Vernon W. Hughes, a Yale physicist whose investigation of particles called muons poked holes in standard subatomic theory and provided evidence for the existence of previously undetected matter, died at Yale-New Haven Hospital last Tuesday" (1/2 page).

  9. Frau Dr Anna Weber—van Bosse, neunzig Jahre

    NARCIS (Netherlands)

    Westerdijk, Johanna

    1942-01-01

    In Eerbeek, in einem der schön gelegenen Dörfer der Provinz Gelderland, steht ein altes Schloss, von der Verkehrsstrasse weit entfernt, und am Bach entlang zu erreichen. Es ist das sogenannte ”Huis Eerbeek“, das Haus der Frau Dr. Weber, die Herrin im wahren Sinne des Wortes. Da können wir heute der

  10. In memoriam dr. Anne van Wijngaarden (1925-2004)

    NARCIS (Netherlands)

    Broekhuizen, S.; Laar, van V.

    2005-01-01

    Op 4 oktober 2004 overleed Dr. Anne van Wijngaarden op 78-jarige leeftijd in zijn huis bij Millac- Carlux, Frankrijk. Hij was een van de Nederlandse oprichters van de Vereniging voor Zoogdierkunde en Zoogdierbescherming. Nadat zijn eindexamen op de middelbare school wilde Anne aanvankelijk geologie

  11. Dr Jacob van der Land, marine biologist extraordinary

    NARCIS (Netherlands)

    Bruggen, van A.C.

    2001-01-01

    This contribution is an attempt to sketch the life and works of Dr Jacob van der Land, curator of worms and chief marine biologist of the National Museum of Natural History, on the occasion of his official retirement. Born in 1935, Jacob van der Land read biology at Leiden University (1958-1964),

  12. Dr. Edward de Bono's Six Thinking Hats and Numeracy

    Science.gov (United States)

    Paterson, Anne

    2006-01-01

    In education, the term "metacognition" describes thinking about thinking. Within mathematics, the term "metacomputation" describes thinking about computational methods and tools. This article shows how Dr. Edward de Bono's Six Thinking Hats can be used to demonstrate metacognition and metacomputation in the primary classroom. The article suggests…

  13. Celebrate the legacy of Dr. Martin Luther King Jr.

    OpenAIRE

    Lazenby, Jenna

    2006-01-01

    In celebration of the life and legacy of Dr. Martin Luther King, Jr., Virginia Tech will host a variety of educational and cultural programs and community service events Jan. 14-19, 2007. All events are free and open to the public.

  14. Dr. Martin Luther King, Jr. Washington State Resource Guide.

    Science.gov (United States)

    Washington Office of the State Superintendent of Public Instruction, Olympia, WA. Div. of Instructional Programs and Services.

    The Washington State Resource Guide on Martin Luther King, Jr., supplies a wide variety of materials for use with all grade levels in classroom and assembly presentations in public schools. The goal is for every child enrolled in Washington State schools to learn about Dr. King during the days of January 15 to January 17. Resolutions supporting an…

  15. A Dr. Martin Luther King, Jr. Curriculum: Playing the Dream.

    Science.gov (United States)

    Clemens, Sydney Gurewitz

    1988-01-01

    Discusses curriculum for young children centered around the beliefs and teachings of Dr. Martin Luther King, Jr. His works are interpreted in a human rights context in which children find their voice in the peaceable resolution of everyday conflicts. Describes the Child of the Day program. (Author/RWB)

  16. Improving College Students English Learning with Dr. Eye Android Mid

    Science.gov (United States)

    Yang, Ju Yin; Che, Pei-Chun

    2015-01-01

    This paper investigates college students' English language learning through use of Dr. Eye Android handheld mobile Internet device (MID). Compared to related studies, students' English learning using MIDs has not been evaluated and fully understood in the field of higher education. Quantitatively, the researchers used TOEIC pretest and posttest to…

  17. Dynamic Star Formation in the Massive DR21 Filament

    Energy Technology Data Exchange (ETDEWEB)

    Schneider, N.; /Saclay; Csengeri, T.; /Saclay; Bontemps, S.; /OASU, Floirac; Motte, F.; /Saclay; Simon, R.; /Cologne U.; Hennebelle, P.; /Paris Observ.; Federrath, C.; /ZAH, Heidelberg; Klessen, R.; /ZAH, Heidelberg /KIPAC, Menlo Park

    2010-08-25

    The formation of massive stars is a highly complex process in which it is unclear whether the star-forming gas is in global gravitational collapse or an equilibrium state supported by turbulence and/or magnetic fields. By studying one of the most massive and dense star-forming regions in the Galaxy at a distance of less than 3 kpc, i.e. the filament containing the well-known sources DR21 and DR21(OH), we attempt to obtain observational evidence to help us to discriminate between these two views. We use molecular line data from our {sup 13}CO 1 {yields} 0, CS 2 {yields} 1, and N{sub 2}H{sup +} 1 {yields} 0 survey of the Cygnus X region obtained with the FCRAO and CO, CS, HCO{sup +}, N{sub 2}H{sup +}, and H{sub 2}CO data obtained with the IRAM 30m telescope. We observe a complex velocity field and velocity dispersion in the DR21 filament in which regions of the highest column-density, i.e., dense cores, have a lower velocity dispersion than the surrounding gas and velocity gradients that are not (only) due to rotation. Infall signatures in optically thick line profiles of HCO{sup +} and {sup 12}CO are observed along and across the whole DR21 filament. By modelling the observed spectra, we obtain a typical infall speed of {approx}0.6 km s{sup -1} and mass accretion rates of the order of a few 10{sup -3} M{sub {circle_dot}} yr{sup -1} for the two main clumps constituting the filament. These massive clumps (4900 and 3300 M{sub {circle_dot}} at densities of around 10{sup 5} cm{sup -3} within 1 pc diameter) are both gravitationally contracting. The more massive of the clumps, DR21(OH), is connected to a sub-filament, apparently 'falling' onto the clump. This filament runs parallel to the magnetic field. Conclusions. All observed kinematic features in the DR21 filament (velocity field, velocity dispersion, and infall), its filamentary morphology, and the existence of (a) sub-filament(s) can be explained if the DR21 filament was formed by the convergence of flows

  18. The DR3(w18),DQw4 Haplotype Differs from DR3(w17),DQw2 Haplotypes at Multiple Class II Loci

    Science.gov (United States)

    1989-01-01

    DR3, members of the DRw52 family, are especially important because of the association of DR3 with a number of autoimmune diseases such as insulin...dependent diabetes, myasthenia gravis, and Graves’ disease [13]. We have begun a study of a DR3 haplotype, DR3(w 18), commonly found in the American...molecules. Proc Nail Acad Sci USA 83:3968, 1986. 5. Ball E, Stastny P: Antigen specific HLA-restriction determinant distinct from HLA-DR. Immunogenetics

  19. Six new DR52-associated DRB1 alleles, three of DR8, two of DR11, and one of DR6, reflect a variety of mechanisms which generate polymorphism in the MHC.

    Science.gov (United States)

    Smith, A G; Nelson, J L; Regen, L; Guthrie, L A; Donadi, E; Mickelson, E M; Hansen, J A

    1996-08-01

    We have sequenced DNA from six new DR52-associated DRB1 alleles initially detected by PCR/SSOP analysis. Three DR8 associated alleles differed from previously known alleles by single nucleotide substitutions. DRB1*0807 and DRB1*0811 both vary from DRB1*08021 at codon 57 resulting in two different amino acids at this residue. DRB1*0807 was identified in samples of Brazilian origin while *0811 was identified among samples from the Tlingit Native American population of Southeast Alaska. DRB1*0814, identified in a family of Chinese origin, differed from DRB1*08032 at codon 12 at both the nucleotide and the amino acid level. In addition, two alleles of DR11, DRB1*1113 and *1119, were each detected in Caucasian individuals. DRB1*1113 differs from other DR11 alleles at codons 37, 67, 70 and 74, while DRB1*1119 differs from *1101 by a single nucleotide substitution at codon 67. Finally, DRB1*1418 was detected in a sample from an Asian or Pacific Islander and shares sequences with several other DR52-associated DRB1 alleles. These six DRB1 alleles appear to have been generated by either gene conversion events, DRB1*1113 and *1418, or by point mutations, DRB1*0814, *0807, *0811 and *1119, although the single nucleotide substitutions found in the latter three alleles are also present in at least one other DRB1 allele and, therefore, could have been the product of gene conversions.

  20. Dr. Anil Kakodkar, Director, Bhabha Atomic Research Centre (BARC), Chairman-Designate of the Atomic Energy Commission Secretary, Department of Atomic Energy, India

    CERN Multimedia

    Patrice Loïez

    2000-01-01

    Photo 01: Dr. A. Kakodkar signing the Guest Book with Dr. L. Evans, LHC Project Leader and Prof. R. Cashmore, Director for Collider Programmes Photo 02: Dr. A. Kakodkar with Dr. L. Evans Photo 03: Dr. A. Kakodkar

  1. 78 FR 29781 - Before Administrative Judges: Ronald M. Spritzer, Chairman, Dr. Anthony J. Baratta, Dr. Randall J...

    Science.gov (United States)

    2013-05-21

    ... COMMISSION Atomic Safety and Licensing Board Before Administrative Judges: Ronald M. Spritzer, Chairman, Dr... submitted to: Mail: Administrative Judge Ronald M. Spritzer, Atomic Safety and Licensing Board Panel, Mail... statement should be sent to the Chairman of this Licensing Board as follows: Mail: Administrative...

  2. HLA-DR-expressing cells and T-lymphocytes in sural nerve biopsies

    DEFF Research Database (Denmark)

    Schrøder, H D; Olsson, T; Solders, G;

    1988-01-01

    was confirmed. HLA-DR expression was found in all biopsies and thus was not restricted to any particular type of neuropathy. The HLA-DR expression appeared to correlate with severity and activity of the neuropathy. HLA-DR-expressing macrophages wrapping myelinated fibers were prominent in primary demyelinating......Thirty-five sural nerve biopsies were stained immunohistochemically for HLA-DR antigen. HLA-DR was expressed on nonmyelinating Schwann cells, macrophages, vascular endothelium, and perineurium. By means of double immunofluorescence staining the identity of the HLA-DR presenting structures...

  3. Dr. Irmfried Eberl (1910-1948): mass murdering MD.

    Science.gov (United States)

    Strous, Rael D

    2009-04-01

    There are isolated cases of physicians who murdered their patients. However, never had a single physician personally supervised the mass murder of hundreds of thousands of individuals, until Dr. Irmfried Eberl. Commander of the Nazi death camp Treblinka, he killed both the ill and those he considered "a disease to his nation." At age 32 Dr. Eberl established Treblinka, where he was responsible for the killing of approximately 280,000 individuals within a few weeks. The position of camp commandant was earned following his success as head of two psychiatric hospitals in Germany where he coordinated the murder of thousands of mentally ill Jews and non-Jews within the context of the euthanasia program. However, few in medicine have heard of him or the harm he caused to the ethical practice of the profession and to human rights.

  4. Redox pioneer: Professor Wulf Dröge.

    Science.gov (United States)

    Kinscherf, Ralf

    2011-06-01

    Dr. Wulf Dröge is recognized here as a redox pioneer because he has published as first author an article on antioxidant/redox biology that has been cited more than 2000 times and over 10 articles that have been cited more than 100 times. One of the key discoveries (1987) was the stimulatory effect of superoxide radicals and hydrogen peroxide on lymphocyte functions, which triggered a series of studies on the role of reactive oxygen species, glutathione, and its precursor cysteine in physiological and pathological processes. He discovered abnormally low cysteine and glutathione levels in human immunodeficiency virus-infected patients and the age-related decline in the postabsorptive plasma cysteine concentration, which is believed to cause age-related oxidative stress. He developed a theoretical concept of the mechanism of aging and death, which is outlined in his books Avoiding the First Cause of Death and Challenging the Limits of the Human Lifespan.

  5. DR Experiments in the 60 years since the Bates paper

    Science.gov (United States)

    Johnsen, Rainer

    2011-07-01

    About 60 years have passed since David Bates in a 1950 Physical Review Letter to the Editor first clarified the dissociative recombination mechanism (DR) of molecular ions and provided the conceptual basis for the process that plays an important role in the ionospheres of Earth and other planets, the interstellar medium, and electrical discharges. His visionary (and characteristically "terse") thumbnail sketch of the DR mechanism only hinted at the subtleties that have kept atomic theorists and experimentalists busy for many years. In my talk, I will focus on experiments on N2+ recombination, beginning with plasma afterglows, and then move on to the "after"-afterglow period that is now dominated by the powerful storage-ring methods.

  6. Peptide binding predictions for HLA DR, DP and DQ molecules

    DEFF Research Database (Denmark)

    Wang, P.; Sidney, J.; Kim, Y.

    2010-01-01

    a significant gap in knowledge as HLA DP and DQ molecules are presumably equally important, and have only been studied less because they are more difficult to handle experimentally. RESULTS: In this study, we aimed to narrow this gap by providing a large scale dataset of over 17,000 HLA-peptide binding......BACKGROUND: MHC class II binding predictions are widely used to identify epitope candidates in infectious agents, allergens, cancer and autoantigens. The vast majority of prediction algorithms for human MHC class II to date have targeted HLA molecules encoded in the DR locus. This reflects...... their performance. CONCLUSION: We found that 1) prediction methodologies developed for HLA DR molecules perform equally well for DP or DQ molecules. 2) Prediction performances were significantly increased compared to previous reports due to the larger amounts of training data available. 3) The presence...

  7. Dr. Harry Whelan With the Light Emitting Diode Probe

    Science.gov (United States)

    1999-01-01

    The red light from the Light Emitting Diode (LED) probe shines through the fingers of Dr. Harry Whelan, a pediatric neurologist at the Children's Hospital of Wisconsin in Milwaukee. Dr. Whelan uses the long waves of light from the LED surgical probe to activate special drugs that kill brain tumors. Laser light previously has been used for this type of surgery, but the LED light illuminates through all nearby tissues, reaching parts of tumors that shorter wavelengths of laser light carnot. The new probe is safer because the longer wavelengths of light are cooler than the shorter wavelengths of laser light, making the LED less likely to injure normal brain tissue near the tumor. Also, it can be used for hours at a time while still remaining cool to the touch. The probe was developed for photodynamic cancer therapy under a NASA Small Business Innovative Research Program grant. The program is part of NASA's Technology Transfer Department at the Marshall Space Flight Center.

  8. Star Formation in the DR21 Region (B)

    Science.gov (United States)

    2004-01-01

    [figure removed for brevity, see original site] Annotated mosaic Hidden behind a shroud of dust in the constellation Cygnus is an exceptionally bright source of radio emission called DR21. Visible light images reveal no trace of what is happening in this region because of heavy dust obscuration. In fact, visible light is attenuated in DR21 by a factor of more than 10,000,000,000,000,000,000,000,000,000,000,000,000,000 (ten thousand trillion heptillion). New images from NASA's Spitzer Space Telescope allow us to peek behind the cosmic veil and pinpoint one of the most massive natal stars yet seen in our Milky Way galaxy. The never-before-seen star is 100,000 times as bright as the Sun. Also revealed for the first time is a powerful outflow of hot gas emanating from this star and bursting through a giant molecular cloud. The upper image is a large-scale mosaic assembled from individual photographs obtained with the InfraRed Array Camera (IRAC) aboard Spitzer. The image covers an area about two times that of a full moon. The mosaic is a composite of images obtained at mid-infrared wavelengths of 3.6 microns (blue), 4.5 microns (green), 5.8 microns (orange) and 8 microns (red). The brightest infrared cloud near the top center corresponds to DR21, which presumably contains a cluster of newly forming stars at a distance of 10,000 light-years. Protruding out from DR21 toward the bottom left of the image is a gaseous outflow (green), containing both carbon monoxide and molecular hydrogen. Data from the Spitzer spectrograph, which breaks light into its constituent individual wavelengths, indicate the presence of hot steam formed as the outflow heats the surrounding molecular gas. Outflows are physical signatures of processes that create supersonic beams, or jets, of gas. They are usually accompanied by discs of material around the new star, which likely contain the materials from which future planetary systems are formed. Additional newborn stars, depicted in green, can be

  9. Dr. John H. Hopps Jr. Research Scholars Program

    Science.gov (United States)

    2014-10-20

    graduates’ majors, honors/awards and their acceptance to a doctoral program. Also, assisting with securing the keynote speaker, Dr. Jimmie Lee Davis, Jr...experiences during school semesters and in the summers, and scholastic information such as college majors, minors, graduations, degree pursuits, fellowships...climate change. The Morehouse Hopps Alumni Panel included seven graduates who are currently in various levels of graduate school. Their candid

  10. 105-DR Large Sodium Fire Facility closure plan. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    1993-05-01

    The Hanford Site, located northwest of the city of Richland, Washington, houses reactors, chemical-separation systems, and related facilities used for the production of special nuclear materials, and activities associated with nuclear energy development. The 105-DR Large Sodium Fire Facility (LSFF), which was in operation from about 1972 to 1986, was a research laboratory that occupied the former ventilation supply room on the southwest side of the 105-DR Reactor facility. The LSFF was established to provide a means of investigating fire and safety aspects associated with large sodium or other metal alkali fires in the liquid metal fast breeder reactor (LMFBR) facilities. The 105-DR Reactor facility was designed and built in the 1950`s and is located in the 100-D Area of the Hanford Site. The building housed the 105-DR defense reactor, which was shut down in 1964. The LSFF was initially used only for engineering-scale alkali metal reaction studies. In addition, the Fusion Safety Support Studies program sponsored intermediate-size safety reaction tests in the LSFF with lithium and lithium lead compounds. The facility has also been used to store and treat alkali metal waste, therefore the LSFF is subject to the regulatory requirements for the storage and treatment of dangerous waste. Closure will be conducted pursuant to the requirements of the Washington Administrative Code (WAC) 173-303-610. This closure plan presents a description of the facility, the history of waste managed, and the procedures that will be followed to close the LSFF as an Alkali Metal Treatment Facility. No future use of the LSFF is expected.

  11. Oxyuriasis at the Department of Pediatrics, Dr. Pirngadi Hospital, Medan.

    Science.gov (United States)

    Hasibuan, B; Naim, M; Lubis, A H; Pasaribu, S; Lubis, C P

    1989-01-01

    During the period of 3 months (February-April 1987), a prospective study on oxyuariasis among children had been conducted at Child Health Department of Dr. Pirngadi Hospital Medan. All children over 8 months of age were included in this study. The diagnosis was based on the modified Scoth's technique. Oxyuriasis ova were found in 21 out 119 children (17.65%). The peak incidence was found in the school age.

  12. 105-DR Large Sodium Fire Facility closure activities evaluation report

    Energy Technology Data Exchange (ETDEWEB)

    Adler, J.G.

    1996-04-22

    This report evaluates the closure activities at the 105-DR Large Sodium Fire Facility. The closure activities discussed include: the closure activities for the structures, equipment, soil, and gravel scrubber; decontamination methods; materials made available for recycling or reuse; and waste management. The evaluation compares these activities to the regulatory requirements and closure plan requirements. The report concludes that the areas identified in the closure plan can be clean closed.

  13. Tindakan Perawatan Dekubitus oleh Perawat di RSUD Dr. Pirngadi Medan

    OpenAIRE

    2014-01-01

    Decubitus treatment is an action in maintaining skin integrity of the patients of bed rest which consists of patients preparation, maintaining hygiene, maintaining moisture, maintaining pressure, assessment, and communication. This research uses descriptive design with the purpose to know the action of decubitus treatment by nurses in RSUD dr. Pirngadi Medan which consists of patients preparation, maintaining hygiene, maintaining moisture, maintaining pressure, assessment, and communication....

  14. DR services in Fiji: attitudes, barriers and screening practices

    Directory of Open Access Journals (Sweden)

    Bridget Kool

    2015-06-01

    Full Text Available The aim of this study was to describe the attitudes and perceptions of primary health care doctors in Fiji regarding the importance of eye care in diabetes mellitus (DM management, to explore current eye care practice, and to investigate awareness and use of relevant clinical practice guidelines. The study builds on earlier research conducted in Fiji that identified a rapid increase of late-stage DR patients presenting for treatment, at a time when surgery was the only option.

  15. Practitioner Profile: An Interview with Dr. Jerry Gale, LMFT

    Directory of Open Access Journals (Sweden)

    Jerry Gale

    2012-06-01

    Full Text Available Dr. Jerry Gale is an Associate Professor and the Clinical Director of the Marriage and Family Therapy Doctoral Program at the University of Georgia. He is a Licensed Marriage and Family Therapist and an approved supervisor of the American Association of Marriage and Family Therapists. He earned a B.A. from the University of Michigan, a MEd from the University of Arizona, and a Ph.D. from Texas Tech University. Over the course of his career, Dr. Gale has authored three books and over 60 articles and book chapters. He is a co-developer of a relational financial therapy approach that combines financial counseling with family therapy and has extensive training in clinical hypnosis, couples therapy, and family therapy, as well as mindfulness meditation. He is the recipient of the American Family Therapy Academy 2006 Outstanding Research Award. In addition to his work at the University of Georgia, Dr. Gale conducts therapy at Athens Associates for Counseling and Psychotherapy.

  16. The Final Kepler Planet Candidate Catalog (DR25)

    Science.gov (United States)

    Coughlin, Jeffrey; Thompson, Susan E.; Kepler Team

    2017-06-01

    We present Kepler's final planet candidate catalog, which is based on the Q1--Q17 DR25 data release and was created to allow for accurate calculations of planetary occurrence rates. We discuss improvements made to our fully automated candidate vetting procedure, which yields specific categories of false positives and a disposition score value to indicate decision confidence. We present the use of light curve inversion and scrambling, in addition to our continued use of pixel-level transit injection, to produce artificial planet candidates and false positives. Since these simulated data sets were subjected to the same automated vetting procedure as the real data set, we are able to measure both the completeness and reliability of the catalog. The DR25 catalog, source code, and a multitude of completeness and reliability data products are available at the Exoplanet Archive (http://exoplanetarchive.ipac.caltech.edu). The DR25 light curves and pixel-level data are available at MAST (http://archive.stsci.edu/kepler).

  17. Dynamic star formation in the massive DR21 filament

    CERN Document Server

    Schneider, N; Bontemps, S; Motte, F; Simon, R; Hennebelle, P; Federrath, C; Klessen, R

    2010-01-01

    The formation of massive stars is a highly complex process in which it is not clear whether the star-forming gas is in global gravitational collapse or in an equilibrium state, supported by turbulence. By studying one of the most massive and dense star-forming regions in the Galaxy at a distance of less than 3 kpc, the filament containing the well-known sources DR21 and DR21(OH), we expect to find observational signatures that allow to discriminate between the two views. We use molecular line data from our 13CO 1-0, CS 2-1, and N2H+ 1-0 survey of the Cygnus X region obtained with the FCRAO and high-angular resolution observations of CO, CS, HCO+, N2H+, and H2CO, obtained with the IRAM 30m telescope. We observe a complex velocity field and velocity dispersion in the DR21 filament in which regions of highest column-density, i.e. dense cores, have a lower velocity dispersion than the surrounding gas and velocity gradients that are not (only) due to rotation. Infall signatures in optically thick line profiles of ...

  18. High Blood Cholesterol Q&A Dr. Michael Lauer | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... high cholesterol research. Dr. Michael Lauer and his wife, Dr. Robin Avery, agree on the health benefits ... trial of the drug methotrexate in high-risk patients with vascular disease. We have come to appreciate ...

  19. Curriculum Vitae of Prof. Dr. Gürer GÜLSEVİN and Prof. Dr. Ayşe İLKER’s Impressions About Him Prof. Dr. Gürer GÜLSEVİN’in Özgeçmişi ve Prof. Dr. Ayşe İLKER’in Onun Hakkındaki İzlenimleri

    Directory of Open Access Journals (Sweden)

    Özgür AY

    2011-01-01

    Full Text Available Curriculum Vitae of Prof. Dr. Gürer GÜLSEVİN and Prof. Dr. Ayşe İLKER’s Impressions About Him Prof. Dr. Gürer GÜLSEVİN’in Özgeçmişi ve Prof. Dr. Ayşe İLKER’in Onun Hakkındaki İzlenimleri

  20. Prospective HLA-DR matching in cadaveric renal transplants: a single center study.

    Science.gov (United States)

    Mendez, R; Iwaki, Y; Mendez, R; Bogaard, T; Self, B

    1983-03-01

    We reviewed 77 potential cadaveric allograft recipients who had undergone prospective HLA-A and B locus and HLA-DR antigen identification. Matching was accomplished, giving first priority to HLA-DR compatibility and relying on HLA-A and B antigen matching only in situations of total HLA-DR incompatibility. Complete HLA-DR identification occurred in 56 per cent of all patients. There were 15 patients (19.5 per cent) who received a 2/2 HLA-DR perfect match, with 86.7 plus or minus 8.8 per cent 1-year actuarial graft survival, and 41 (53 per cent) who received a 1/2 HLA-DR match, with 58.2 plus or minus 7.8 per cent 1-year actual allograft survival. Finally, 21 patients (27 per cent) received a 0/2 HLA-DR match, with 64.9 plus or minus 10.7 per cent actual survival. These results and their mirrored mismatching results showed statistically significant allograft success in only the HLA-DR 2/2 matches. Matching for HLA 2 DR donors proved a statistically significant success over the other HLA-DR allograft matches and the older controversial matching system based on HLA-A and B locus antigens. The restricted gene polymorphism of the HLA-DR systems allows for a relatively high percentage of perfect HLA-DR matches.

  1. Enhancing Price Response Programs through Auto-DR: California's 2007 Implementation Experience

    Energy Technology Data Exchange (ETDEWEB)

    Kiliccote, Sila; Wikler, Greg; Chiu, Albert; Piette, Mary Ann; Kiliccote, Sila; Hennage, Dan; Thomas, Chuck

    2007-12-18

    This paper describes automated demand response (Auto-DR) activities, an innovative effort in California to ensure that DR programs produce effective and sustainable impacts. Through the application of automation and communication technologies coupled with well-designed incentives and DR programs such as Critical Peak Pricing (CPP) and Demand Bidding (DBP), Auto-DR is opening up the opportunity for many different types of buildings to effectively participate in DR programs. We present the results of Auto-DR implementation efforts by the three California investor-owned utilities for the Summer of 2007. The presentation emphasizes Pacific Gas and Electric Company's (PG&E) Auto-DR efforts, which represents the largest in the state. PG&E's goal was to recruit, install, test and operate 15 megawatts of Auto-DR system capability. We describe the unique delivery approaches, including optimizing the utility incentive structures designed to foster an Auto-DR service provider community. We also show how PG&E's Critical Peak Pricing (CPP) and Demand Bidding (DBP) options were called and executed under the automation platform. Finally, we show the results of the Auto-DR systems installed and operational during 2007, which surpassed PG&E's Auto-DR goals. Auto-DR is being implemented by a multi-disciplinary team including the California Investor Owned Utilities (IOUs), energy consultants, energy management control system vendors, the Lawrence Berkeley National Laboratory (LBNL), and the California Energy Commission (CEC).

  2. Dr. Wernher Von Braun greeting dignitaries at the Redstone Arsenal airfield.

    Science.gov (United States)

    1999-01-01

    Dr. George E. Mueller, center, associate administrator for manned space flight, is flanked by Dr. Wernher Von Braun, left, and Dr. Eberhard Rees at the Redstone Arsenal airstrip. the associate adminstrator was making his annual staff visit to the Marshall Space Flight Center.

  3. Diffusely adherent Escherichia coli strains expressing Afa/Dr adhesins (Afa/Dr DAEC): hitherto unrecognized pathogens.

    Science.gov (United States)

    Le Bouguénec, Chantal; Servin, Alain L

    2006-03-01

    Diffusely adherent Escherichia coli (DAEC) strains are currently considered to constitute a putative sixth group of diarrheagenic E. coli. However, on the basis of their diffuse adherence to HEp-2 and HeLa cells, the detection of afa/dra/daa-related operons encoding this adherence phenotype, and the mobilization of decay-accelerating factor, both commensal and pathogenic strains can be classified as Afa/Dr DAEC isolates. Furthermore, strains associated with diarrheal diseases and strains causing extra-intestinal infections can also be identified as Afa/Dr DAEC strains. Although several cell signaling events that occur after epithelial cells have been infected by Afa/Dr DAEC have been reported, the pathophysiological processes that allow intestinal and extra-intestinal infections to develop are not fully understood. This review focuses on the genetic organization of the afa/dra/daa-related operons and on the virulence factors that trigger cellular responses, some of which are deleterious for the host cells. Finally, this review suggests future lines of research that could help to elucidate these questions.

  4. Human immune responsiveness to Lolium perenne pollen allergen Lol p III (rye III) is associated with HLA-DR3 and DR5.

    Science.gov (United States)

    Ansari, A A; Freidhoff, L R; Meyers, D A; Bias, W B; Marsh, D G

    1989-05-01

    A well-characterized allergen of Lolium perenne (perennial rye grass) pollen, Lol p III, has been used as a model antigen to study the genetic control of the human immune response. Associations between HLA type and IgE or IgG antibody (Ab) responsiveness to Lol p III were studied in two groups of skin-test-positive Caucasoid adults (N = 135 and 67). We found by nonparametric and parametric analyses that immune responsiveness to Lol p III was significantly associated with HLA-DR3 and DR5. No association was found between any DQ type and immune responsiveness to Lol p III. Geometric mean IgE or IgG Ab levels to Lol p III were not different between B8+, DR3+ subjects and B8-, DR3+ subjects, showing that HLA-B8 had no influence on the association. Lol p III IgG Ab data obtained on subjects after grass antigen immunotherapy showed that 100% of DR3 subjects and 100% of DR5 subjects were Ab+. A comparison of all the available protein sequences of DRB gene products showed that the first hypervariable region of DR3 and DR5 (and DRw6), and no other region, contains the sequence Glu9-Tyr-Ser-Thr-Ser13. Our observations are consistent with the possibility that immune responsiveness to the allergen Lol p III is associated with this amino acid sequence in the first hypervariable region of the DR beta 1 polypeptide chain.

  5. Discourse Analysis of Dr. Mahathir’s Business Speech

    Directory of Open Access Journals (Sweden)

    Aliakbar Imani

    2015-10-01

    Full Text Available Discourse analysis is one of the methods of identifying ideologies reflected in text as well as the communication strategies used to convey those ideologies effectively to the addressed audience. Political business speeches defined as ‘a relatively autonomous discourse produced orally by a politician in front of an audience with the main purpose of persuading the audience into accepting a business proposition’ can be a good source to understand (a the dominant business ideologies in a country, and (b the reasons of success or failure of a political leader in conveying his/her business ideologies and/or justifying his/her business proposition. Hence, this article was aimed to identify Dr. Mahathir’s ideologies on Asia-Europe business relationships as well as the communication strategies he used to convey his ideologies to the audience. Analyzing one of Dr. Mahathir’s speeches delivered at an international business summit in the year 2000 revealed some of his ideologies with regard to Euro-Asia business relationships as well as the communication strategies he used to convey these ideologies to the audience. In this speech, Dr. Mahathir strongly believes in ‘equal power in Euro-Asia relationships’ as well as ‘unity and solidarity among Asian countries’ as the two main ideologies in this speech; and he tries to convey these ideologies by ‘referring to the bitter history of Euro-Asia relationships’ as well as ‘using pronouns’ as the two salient strategies used in this speech.

  6. A "new" primed lymphocyte typing (PLT) defined DP-antigen associated with a private HLA--DR antigen

    DEFF Research Database (Denmark)

    Morling, N; Jakobsen, B K; Platz, P

    1980-01-01

    We have recently described a "new" private HLA-DR antigen, DR"LTM", which has a frequency of approximately 0.6% in Danes. Primed Lymphocyte Typing (PLT) cells directed towards DR"LTM"-associated determinants were generated in vitro by haplotype primings in two unrelated families with DR"LTM" posi......We have recently described a "new" private HLA-DR antigen, DR"LTM", which has a frequency of approximately 0.6% in Danes. Primed Lymphocyte Typing (PLT) cells directed towards DR"LTM"-associated determinants were generated in vitro by haplotype primings in two unrelated families with DR...

  7. Progress in inflammatory neuropathy -the legacy of Dr Jack Griffin.

    Science.gov (United States)

    Feldman, Eva L; Hughes, Richard A C; Willison, Hugh J

    2015-11-01

    The past quarter of a century has brought incredible advances in our understanding of inflammatory neuropathies, and the insights into Guillain-Barré syndrome (GBS) began in the 1990s with the seminal work of Dr Jack Griffin and his colleagues. In this essay, we provide a tribute to Jack, and review the recent progress in a field that he termed his personal favourite. In particular, we discuss the new developments in our understanding and diagnosis of inflammatory neuropathies, the recent emergence of the node of Ranvier and the paranode as sites of intensive investigation, and the mechanistic evidence that is providing a platform for therapeutic development studies.

  8. The UV-bright Quasar Survey (UVQS): DR1

    CERN Document Server

    Monroe, TalaWanda R; Tejos, N; Worseck, G; Hennawi, Joseph F; Schmidt, Tobias; Tumlinson, Jason; Shen, Yue

    2016-01-01

    We present the first data release (DR1) from our UV-bright Quasar Survey (UVQS) for new $z \\sim 1$ active galactic nuclei (AGN) across the sky. Using simple GALEX UV and WISE near-IR color selection criteria, we generated a list of 1450 primary candidates with $FUV 0.5$. Including a small set of observed secondary candidates, we report the discovery of 217 AGN with $FUV < 18$ mag that had no previously reported spectroscopic redshift. These are excellent potential targets for UV spectroscopy before the end of the {\\it Hubble Space Telescope} mission. The main data products are publicly released through the Mikulski Archive for Space Telescopes.

  9. Dr. von Braun on the Mobility Test Article (MTA)

    Science.gov (United States)

    1966-01-01

    In this June 1966 photograph, Marshall Space Flight Center Director Dr. Wernher von Braun test-drives the Mobility Test Article (MTA), a developmental vehicle built by the Bendix Corporation to test lunar mobility vehicle concepts. The data provided by the MTA helped in designing the Lunar Roving Vehicle (LRV), developed under the direction of the MSFC. The LRV was designed to allow Apollo astronauts a greater range of mobility during lunar exploration missions. The LRVs were deployed during the last three Apollo missions; Apollo 15, Apollo 16, and Apollo 17.

  10. Puesta en valor del fondo particular Dr. Guillermo A. Bibiloni

    OpenAIRE

    Amicuzzi, Silvia Andrea; Canaparo, Juan Francisco; Lasarte, Martín Jorge; Leoz, María Mercedes; Paladini, Rafaela Irene

    2013-01-01

    La puesta en valor del fondo particular “Dr. Guillermo A. Bibiloni”, docente e investigador de Física, abarcó las tareas de conservación de la documentación y del material bibliográfico que lo forman, dígase acondicionamientos, digitalización y difusión, para disponerlo a la consulta o darlo a conocer, tanto al público especializado como también al público en general, dadas las varias temáticas que lo constituye.

  11. Mediastinal pathology and the contributions of Dr. Juan Rosai.

    Science.gov (United States)

    Wick, Mark R

    2016-09-01

    Dr. Juan Rosai is one of the most prolific contributors to the literature on mediastinal pathology, and he has added steadily to that body of work over a 50-year period. Rosai has written several landmark articles in this topical area, including articles on thymic epithelial lesions, mediastinal neuroendocrine tumors, mediastinal lymphoma and other hematopoietic lesions, thymolipoma, thymoliposarcoma, mediastinal solitary fibrous tumor, intrathymic langerhans-cell histiocytosis, mediastinal germ cell neoplasms, and multilocular thymic cyst. This review recounts his role as one of the principal figures in the surgical pathology of mediastinal diseases.

  12. Državni notranji revizorji in varnost informacijskih sistemov

    OpenAIRE

    Berkopec, Janez

    2015-01-01

    Na področju informacijske tehnologije je edina stalnica to, da se vse stalno spreminja. Ni več organizacije, posebej pa ne v okviru državne uprave, ki ne uporablja informacijske tehnologije pri svojem poslovanju. Ker se stalno posodabljajo stari informacijski sistemi oziroma uvajajo novi, je treba posvetiti posebno pozornost delovanju notranjih kontrol na tem področju, saj le vzpostavljene in pravilno delujoče notranje kontrole na vseh področjih zagotavljajo, da so podatki pravilni in zaneslj...

  13. Prof dr J H Koekemoer as kerkman en akademikus

    Directory of Open Access Journals (Sweden)

    P. J. van der Merwe

    2000-01-01

    Full Text Available Prof Dr J H Koekemoer in service of church and university. Prof Johannes Hendrik Koekemoer's career as minister of the Nederduitsch Hervormde Kerk started in 1960. In 1989 he became a full member and in 1992 Dean of the Faculty of Theology (Section A, Universiteit of Pretoria. This second part of his career ended on 31 December 1999 when he retired. He played a major role in the restructuring and amalgamation of the Faculty of Theology. The article reviews his work and contribution in both fields of church and university.

  14. Dr. Gotthold Steiner (1886-1961): versatile nematologist.

    Science.gov (United States)

    Esser, R P

    1996-01-01

    Swiss-born Dr. Gotthold Steiner was a pioneer in formulating the discipline of nematology. He worked with the American nematologist NA Cobb and together they were responsible for acceptance of the concept of nematode phytoparasites. Steiner had special expertise in anatomy, morphology, phytonematology, marine nematodes, nutrition, mermithids, and selected invertebrate taxa. He authored 191 scientific papers, established the ubiquitous phytoparasitic genus Helicotylenchus, described the pinewood nematode, and did significant work with three important economic pests, Ditylenchus dipsaci, Heterodera rostochiensis, and H. schachtii. He was responsible for introducing training programs in nematology in USDA laboratories.

  15. Dr. von Braun on the Mobility Test Article (MTA)

    Science.gov (United States)

    1966-01-01

    In this June 1966 photograph, Marshall Space Flight Center Director Dr. Wernher von Braun test-drives the Mobility Test Article (MTA), a developmental vehicle built by the Bendix Corporation to test lunar mobility vehicle concepts. The data provided by the MTA helped in designing the Lunar Roving Vehicle (LRV), developed under the direction of the MSFC. The LRV was designed to allow Apollo astronauts a greater range of mobility during lunar exploration missions. The LRVs were deployed during the last three Apollo missions; Apollo 15, Apollo 16, and Apollo 17.

  16. DR Resources for Energy and Ancillary Services in the West (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Hummon, M.; Kiliccote, S.

    2014-04-01

    Demand response (DR) resources present a potentially important source of grid flexibility however, DR in grid models is limited by data availability and modeling complexity. This presentation focuses on the co-optimization of DR resources to provide energy and ancillary services in a production cost model of the Colorado "test system". We assume each DR resource can provide energy services by either shedding load or shifting its use between different times, as well as operating reserves: frequency regulation, contingency reserve, and flexibility (or ramping) reserve. There are significant variations in the availabilities of different types of DR resources, which affect both the operational savings as well as the revenue for each DR resource. The results presented include the system-wide avoided fuel and generator start-up costs as well as the composite revenue for each DR resource by energy and operating reserves.

  17. Dr. Mostafa Moin, Minister of Science, Research and Technology, Islamic Republic of Iran

    CERN Multimedia

    Patrice Loïez

    2001-01-01

    L. to. r.:Dr Henrik Foeth, Team Leader, CMS experiment; Dr Daniel Denegri, Physics Coordinator, CMS experiment; Prof. Tejinder Virdee, Deputy Spokesman, CMS experiment; Prof. Luciano Maiani, CERN Director-General (signing); Mr Jean-Marie Dufour, Head of the Legal Service, Mr Ghodratollah Habibpour Gharakol (back); Dr Abdolali Sharghi, Advisor to the Minister and Director General, Office of International Scientific Cooperation, Ministry of Science, Research and Technology; Dr Mostafa Moin, Minister of Science, Research and Technology, Islamic Republic of Iran (signing); Dr Reza Mansouri, Director, International Scientific Meetings Office, Ministry of Science, Research and Technology; H. E. Dr Ali Khorram, Extraordinary and plenipotentiary Ambassador to the United Nations in Geneva and Dr Hans F. Hoffmann, CERN Director for Technology Transfer & for Scientific Computing. _

  18. Clinical and molecular studies in full trisomy 22: Further delineation of the phenotype and review of the literature. Reply to Dr. Robinson and Dr. Kalousek

    Energy Technology Data Exchange (ETDEWEB)

    Bacino, C.A.; Graham, J.M. Jr. [UCLA School of Medicine, Los Angeles, CA (United States)

    1996-03-01

    This {open_quotes}Letter to the Editor{close_quotes} responds to the comments by Dr. Robinson and Dr. Kalousek regarding the implications of meiotic versus somatic chromosomal aberrations. The survival time of the patient may depend on the detection of mosicism; the discussion of the existence of full trisomy 22 remains controversial. 2 refs.

  19. Zašto postoje države-nacije, a ne svjetska država? Prilog raspravi o teoriji moderne Jacquesa Bideta

    OpenAIRE

    Katunarić, Vjeran

    2009-01-01

    U ovom se članku kritički razmatraju odgovori na pitanja “Zašto postoje države- nacije?”, odnosno “Zašto ne samo jedna država-nacija?”, koje je Jacques Bidet dao u svom djelu Opća teorije moderne. U prvom dijelu članka razmatra se Bidetova analogija između nastanka nacija-država i složenijih država poput EU-a, a napose mogućnosti stvaranja svjetske demokratske države koju je Bidet na inovativan način zamislio kao jamca jednakosti među narodima. S obzirom na normativni karakt...

  20. Show: Dr. H, the life and death of pancakes

    CERN Multimedia

    2012-01-01

    Dr. H, the life and death of pancakes, a comic theatrical creation, written and performed by Heiko Buchholz.   Monday 2 April 2012 in German Tuesday 3 April 2012 in English Wednesday 4 April 2012 in French 8:30 p.m. at the Globe of Science and Innovation. This production takes a comic look at scientific methods, as applied to a common object: the pancake. More specifically, Dr H. regales his audience with statistics, experiments and scientific data surrounding this egg-and-milk-based culinary delight. And although these zany sketches are nothing short of absurd, the audience is drawn in more often than you might expect… and taken on quite an unexpected journey into the behavioural disorders, personality quirks and psychoanalysis of the base pancake. This show playfully mocks scientific logic and discourse, forcing the audience to reflect on their gullibility in the face of science and its impenetrable jargon. It purports to be neither explanation nor illustration of scientific fact,...

  1. CENSUS OF BLUE STARS IN SDSS DR8

    Energy Technology Data Exchange (ETDEWEB)

    Scibelli, Samantha [Burnt Hills-Ballston Lake High School, 88 Lake Hill Road, Ballston, NY 12027 (United States); Newberg, Heidi Jo; Carlin, Jeffrey L. [Department of Physics, Applied Physics and Astronomy, Rensselaer Polytechnic Institute, 110 8th Street, Troy, NY 12180 (United States); Yanny, Brian, E-mail: heidi@rpi.edu [Experimental Astrophysics Group, Fermi National Accelerator Laboratory, P.O. Box 500, Batavia, IL 60510 (United States)

    2015-01-01

    We present a census of the 12,060 spectra of blue objects ((g – r){sub 0} < –0.25) in the Sloan Digital Sky Survey (SDSS) Data Release 8 (DR8). As part of the data release, all of the spectra were cross-correlated with 48 template spectra of stars, galaxies, and QSOs to determine the best match. We compared the blue spectra by eye to the templates assigned in SDSS DR8. 10,856 of the objects matched their assigned template, 170 could not be classified due to low signal-to-noise ratio, and 1034 were given new classifications. We identify 7458 DA white dwarfs, 1145 DB white dwarfs, 273 rarer white dwarfs (including carbon, DZ, DQ, and magnetic), 294 subdwarf O stars, 648 subdwarf B stars, 679 blue horizontal branch stars, 1026 blue stragglers, 13 cataclysmic variables, 129 white dwarf-M dwarf binaries, 36 objects with spectra similar to DO white dwarfs, 179, quasi-stellar objects (QSOs), and 10 galaxies. We provide two tables of these objects, sample spectra that match the templates, figures showing all of the spectra that were grouped by eye, and diagnostic plots that show the positions, colors, apparent magnitudes, proper motions, etc., for each classification. Future surveys will be able to use templates similar to stars in each of the classes we identify to automatically classify blue stars, including rare types.

  2. Radio Continuum and Methanol Observations of DR21(OH)

    CERN Document Server

    Araya, Esteban D; Hofner, Peter; Linz, Hendrik

    2009-01-01

    We report high sensitivity sub-arcsecond angular resolution observations of the massive star forming region DR21(OH) at 3.6, 1.3, and 0.7 cm obtained with the Very Large Array. In addition, we conducted observations of CH3OH 44 GHz masers. We detected more than 30 new maser components in the DR21(OH) region. Most of the masers appear to trace a sequence of bow-shocks in a bipolar outflow. The cm continuum observations reveal a cluster of radio sources; the strongest emission is found toward the molecular core MM1. The radio sources in MM1 are located about 5" north of the symmetry center of the CH3OH outflow, and therefore, they are unlikely to be associated with the outflow. Instead, the driving source of the outflow is likely located in the MM2 core. Although based on circumstantial evidence, the radio continuum from MM1 appears to trace free-free emission from shock-ionized gas in a jet. The orientation of the putative jet in MM1 is approximately parallel to the CH3OH outflow and almost perpendicular to th...

  3. 2009 AMCA Memorial Lecture Honoree: Dr. Chester Lamar Meek.

    Science.gov (United States)

    Connelly, C Roxanne

    2009-09-01

    Chester Lamar Meek (1944-2000), 2009 AMCA Memorial Lecture Honoree, was husband to Sharon Kay Meek, father of Bradley Lamar and Jody Keith, and a member of the faculty of Louisiana State University for 25 years when he passed away on June 27, 2000, while conducting field research on mosquitoes in Cleveland, Mississippi. Dr. Meek was born in Monticello, Arkansas, and attended Ouachita Baptist University, University of Arkansas, and Texas A&M University, where he took his B.S., M.S., and Ph.D., respectively. He was an expert in the biology and control of rice-field mosquitoes and in forensic entomology. He served in the medical service corps of the US Army, authored or co-authored over 65 scientific publications, and was mentor to graduate students in medical and forensic entomology. Dr. Meek was a member of the Louisiana Mosquito Control Association, the Texas Mosquito Control Association, the American Mosquito Control Association, the Entomological Society of America, the American Registry of Professional Entomologists, and the Society for Vector Ecology. He received the American Mosquito Control Association's awards for Meritorious Service (1986) and the Memorial Lectureship Award (1991) and was recognized for his service by the Louisiana Mosquito Control Association with the 1989 Hathaway-Ritter Distinguished Achievement award.

  4. Pathogenesis of human diffusely adhering Escherichia coli expressing Afa/Dr adhesins (Afa/Dr DAEC): current insights and future challenges.

    Science.gov (United States)

    Servin, Alain L

    2014-10-01

    The pathogenicity and clinical pertinence of diffusely adhering Escherichia coli expressing the Afa/Dr adhesins (Afa/Dr DAEC) in urinary tract infections (UTIs) and pregnancy complications are well established. In contrast, the implication of intestinal Afa/Dr DAEC in diarrhea is still under debate. These strains are age dependently involved in diarrhea in children, are apparently not involved in diarrhea in adults, and can also be asymptomatic intestinal microbiota strains in children and adult. This comprehensive review analyzes the epidemiology and diagnosis and highlights recent progress which has improved the understanding of Afa/Dr DAEC pathogenesis. Here, I summarize the roles of Afa/Dr DAEC virulence factors, including Afa/Dr adhesins, flagella, Sat toxin, and pks island products, in the development of specific mechanisms of pathogenicity. In intestinal epithelial polarized cells, the Afa/Dr adhesins trigger cell membrane receptor clustering and activation of the linked cell signaling pathways, promote structural and functional cell lesions and injuries in intestinal barrier, induce proinflammatory responses, create angiogenesis, instigate epithelial-mesenchymal transition-like events, and lead to pks-dependent DNA damage. UTI-associated Afa/Dr DAEC strains, following adhesin-membrane receptor cell interactions and activation of associated lipid raft-dependent cell signaling pathways, internalize in a microtubule-dependent manner within urinary tract epithelial cells, develop a particular intracellular lifestyle, and trigger a toxin-dependent cell detachment. In response to Afa/Dr DAEC infection, the host epithelial cells generate antibacterial defense responses. Finally, I discuss a hypothetical role of intestinal Afa/Dr DAEC strains that can act as "silent pathogens" with the capacity to emerge as "pathobionts" for the development of inflammatory bowel disease and intestinal carcinogenesis.

  5. Pathogenesis of Human Diffusely Adhering Escherichia coli Expressing Afa/Dr Adhesins (Afa/Dr DAEC): Current Insights and Future Challenges

    Science.gov (United States)

    2014-01-01

    SUMMARY The pathogenicity and clinical pertinence of diffusely adhering Escherichia coli expressing the Afa/Dr adhesins (Afa/Dr DAEC) in urinary tract infections (UTIs) and pregnancy complications are well established. In contrast, the implication of intestinal Afa/Dr DAEC in diarrhea is still under debate. These strains are age dependently involved in diarrhea in children, are apparently not involved in diarrhea in adults, and can also be asymptomatic intestinal microbiota strains in children and adult. This comprehensive review analyzes the epidemiology and diagnosis and highlights recent progress which has improved the understanding of Afa/Dr DAEC pathogenesis. Here, I summarize the roles of Afa/Dr DAEC virulence factors, including Afa/Dr adhesins, flagella, Sat toxin, and pks island products, in the development of specific mechanisms of pathogenicity. In intestinal epithelial polarized cells, the Afa/Dr adhesins trigger cell membrane receptor clustering and activation of the linked cell signaling pathways, promote structural and functional cell lesions and injuries in intestinal barrier, induce proinflammatory responses, create angiogenesis, instigate epithelial-mesenchymal transition-like events, and lead to pks-dependent DNA damage. UTI-associated Afa/Dr DAEC strains, following adhesin-membrane receptor cell interactions and activation of associated lipid raft-dependent cell signaling pathways, internalize in a microtubule-dependent manner within urinary tract epithelial cells, develop a particular intracellular lifestyle, and trigger a toxin-dependent cell detachment. In response to Afa/Dr DAEC infection, the host epithelial cells generate antibacterial defense responses. Finally, I discuss a hypothetical role of intestinal Afa/Dr DAEC strains that can act as “silent pathogens” with the capacity to emerge as “pathobionts” for the development of inflammatory bowel disease and intestinal carcinogenesis. PMID:25278576

  6. [Portrait of Dr Milenko Petrović (1884-1950)].

    Science.gov (United States)

    Kljaić, Leposava; Borota, Radoslav

    2008-01-01

    Dr Milenko Petrović was one of the very distinguished physicians in the history of Sombor city, who significantly contributed to the development of health care in Voivodina. His father Dimitrije was a professor in the High Teacher-training School in Sombor, recognized writer and politician of his epoch. He was born in Sombor in 1884, where he was educated and finished grammar school. For medical studies he moved to Budapest as a boarder of the famous Tekelianum, and graduated in 1908. He started specialisation in surgery, but being a great patriot he voluntarily recruited in the Serbian army to fight in Balkan liberation wars against Turkey. For his excellent work as a war surgeon he obtained many recognitions. After completing specialization in surgery in Debrecin, he returned to his native city Sombor, where he intended to practice as a physician, but because af the outbreak of the first world he was mobilized and sent to the front in Galicia. After the war he again returned to Sombor where he was immediatelly nominated for the main county physician and then begins his fruitful many year's work on the establishment and promotion of the health care in Sombor and broader territory. As the main county phsician he initiated the foundation and construction of the hospital in Sombor, because of high mortality rate among children, and spreading of contagious diseases like tuberculosis and trachoma. The construction of the hospital was completed in 1925 and Dr. Petrović was appointed its first director and this duty he performed for many years till the World War 2 in 1941. Under his management the hospital in Sombor became one of the best quality hospitals in the country and gave a big contribution to the promotion of health of the inhabitants of Voivodina. In spite of his extensive duties in the hospital. Dr. Milenko Petrović was very much engaged in social work, as the president of library "Laza Kosti ć". in the Soko association, Fire brigade, Rotary club, and he

  7. Hepatitis C virus sensitizes host cells to TRAIL-induced apoptosis by up-regulating DR4 and DR5 via a MEK1-dependent pathway.

    Directory of Open Access Journals (Sweden)

    Zhongfan Deng

    Full Text Available BACKGROUND: Hepatitis C virus (HCV is the leading cause of liver fibrosis, cirrhosis and hepatocellular carcinoma. It is believed that continuous liver cell apoptosis contributes to HCV pathogenesis. Recent studies have shown that HCV infection can sensitize host cells to TNF-related apoptosis-inducing ligand (TRAIL induced apoptosis, but the mechanism by which HCV regulates the TRAIL pathway remains unclear. METHODS AND RESULTS: Using a sub-genomic replicon and full length virus, JFH-1, we demonstrate that HCV can sensitize host cells to TRAIL-induced apoptosis by up-regulating two TRAIL receptors, death receptor 4 (DR4 and death receptor 5 (DR5. Furthermore, the HCV replicon enhanced transcription of DR5 via Sp1, and the HCV-mediated up-regulation of DR4 and DR5 required MEK1 activity. HCV infection also stimulated the activity of MEK1, and the inhibition of MEK1 activity or the knockdown of MEK1 increased the replication of HCV. CONCLUSIONS: Our studies demonstrate that HCV replication sensitizes host cells to TRAIL-induced apoptosis by up-regulating DR4 and DR5 via a MEK1 dependent pathway. These findings may help to further understand the pathogenesis of HCV infection and provide a therapeutic target.

  8. [Interculturality in the medical practice of Dr. Albert Schweitzer].

    Science.gov (United States)

    Campos-Navarro, Roberto; Ruiz-Llanos, Adriana

    2004-01-01

    Albert Schweitzer (1875-1965) was a young and promising German who at age 29 decided to undertake the profession of Medical Doctor at the University of Strassburg after finishing a career in musical studies in Paris (1899) and obtaining in Berlin a doctoral degree in Philosophy and Theology. Surprisingly, Albert Schweitzer, despite his comfortable life in Europe, decided in 1913 to practice his medical career in a remote and small Equatorial African country. He devoted nearly 50 years of his life caring for the Black population at Lamaberene, where he built a hospital. In this paper, we attempt to develop some theoretical aspects related with interculturality in the medical practice of Dr. Albert Schweitzer. We begin by considering certain sociocultural variables in hospitals that give care to patients with cultural characteristics that are substantially different from those of the health care personnel who organize, administer, and execute medical functions.

  9. Dr. Arthur Conan Doyle and the case of congenital syphilis.

    Science.gov (United States)

    Silverstein, Arthur M; Ruggere, Christine

    2006-01-01

    In 1894, Dr. Arthur Conan Doyle wrote "The Third Generation," a short story involving the transmission of congenital syphilis from generation to generation. Analysts of his writings have interpreted the pathogenetic mechanism involved in modern terms: infection of mother by father and then transplacental infection of the fetus. However, a review of the contemporary literature and the history of the concepts of congenital and "hereditary" syphilis demonstrates that the late 19th-century understanding of the process involved a Lamarckian transmission of paternal infection, via the sperm at the moment of conception. It was undoubtedly this concept that Doyle learned in medical school in the late 1870s and that provided the background to his story.

  10. GPS/DR Error Estimation for Autonomous Vehicle Localization.

    Science.gov (United States)

    Lee, Byung-Hyun; Song, Jong-Hwa; Im, Jun-Hyuck; Im, Sung-Hyuck; Heo, Moon-Beom; Jee, Gyu-In

    2015-08-21

    Autonomous vehicles require highly reliable navigation capabilities. For example, a lane-following method cannot be applied in an intersection without lanes, and since typical lane detection is performed using a straight-line model, errors can occur when the lateral distance is estimated in curved sections due to a model mismatch. Therefore, this paper proposes a localization method that uses GPS/DR error estimation based on a lane detection method with curved lane models, stop line detection, and curve matching in order to improve the performance during waypoint following procedures. The advantage of using the proposed method is that position information can be provided for autonomous driving through intersections, in sections with sharp curves, and in curved sections following a straight section. The proposed method was applied in autonomous vehicles at an experimental site to evaluate its performance, and the results indicate that the positioning achieved accuracy at the sub-meter level.

  11. Musikvideo og tilskuer: Fjernsyn, ideologi og drøm

    Directory of Open Access Journals (Sweden)

    Marsha Kinder

    1987-08-01

    Full Text Available Denne artikel af Marcha Kinder er allerede en klassiker. I næsten al litteratur om musikvideoer henvises der til den - også herhjemme. Det er især hendes typologi over musikvideoerne, som der refereres til, mens artiklens percep- tionspsykologiske sammenligninger mellem musikvideoer og drømme næsten ikke har været inddraget i debatten. Marcha Kinder har arbejdet med medier i en årrække og udgav sammen med Beverle Houston "Self and Cinema A Transformalist Perspective" /(Redgrave Publishing Vompany i 1980. Artiklen "Musikvideo og tilskuer" er oversat i sin helhed fra "Music Video and the Spectator": Television, Ideology and Dream, Film Quarterly, vol. XXXVIII, no. I 1984 af Jim Høyer.

  12. In Memoriam: Prof. Dr Dragutin Djurovic (1937-2013)

    Science.gov (United States)

    2013-12-01

    Prof. dr Dragutin Djurovic was born in Guca, Serbia, on December 20, 1937. He completed his primary and secondary education in Guca and Cacak. In the period 1956-1958, he studied at the General Military Academy in Belgrade. He enrolled at the Faculty of Sciences and Mathematics - Astronomy Group in 1958 and graduated in 1963. After graduation he went to study visits to Paris (1966) and Bruxelles (1972 and 1975). He obtained his MSc degree in 1970 from the University of Belgrade with a thesis entitled "Application of different types of telescopes for astronomical determination of time". His supervisor for the master thesis was Prof. Zaharije Brkic. Dragutin Djurovic defended his PhD thesis "Contribution to determination of Earth-rotation variations and polar motion" at the University of Belgrade in 1974. Most of the thesis-related research was done in Bruxelles during 1972 under the supervision of Prof. Paul Melchior.

  13. Revisiting the Hubble sequence in the SDSS DR7

    Science.gov (United States)

    Huertas-Company, M.; Aguerri, J. A. L.; Bernardi, M.; Mei, S.; S´Nchez Almeida, J.

    2011-11-01

    We present an automated morphological classification in 4 types (E, S0, Sab, Scd) of ˜ 700,000 galaxies from the SDSS DR7 spectroscopic sample based on support vector machines. The main new property of the classification is that we associate a probability to each galaxy of being in the four morphological classes instead of assigning a single class. The classification is therefore better adapted to nature where we expect a continuous transition between different morphological types. The algorithm is trained with a visual classification and then compared to several independent visual classifications including the Galaxy Zoo first-release catalog. We find a very good correlation between the automated classification and classical visual ones. The compiled catalog is intended for use in different applications and is therefore publicly available through a dedicated webpage (http://gepicom04.obspm.fr/sdss_morphology/Morphology_2010.html)

  14. Mr. Jan Hendrik Bannier and Dr. Gosta Funke

    CERN Multimedia

    1966-01-01

    (on the left) : Mr. Jan Hendrik Bannier has been President of the Council at CERN for the years 1964, 1965 and 1966 and was President of the Finance Committee from 1958 to 1960. He is now a member of the Site Evaluation Panel for the 300 GeV accelerator project. In the Netherlands, he is Director of ZWO (Organization for the Advancement of Pure Research) and also Vice-President of the National Commission for UNESCO. (on the right) : Dr. Gosta Funke, who has represented his country at CERN Council sessions since the beginning of the Organization, was elected President of the Council for 1967 at its Thirty-third Session, in December. In Sweden, he has been Secretary-General of the State Council for Atomic Research since 1959. He is also President of the Council of ESO (European Southern Observatory), an organization building in Chili.

  15. Searching for Classical Be Stars from the LAMOST DR1

    CERN Document Server

    Lin, C C; Chen, L; Shao, Z Y; Zhong, J; Yu, P C

    2015-01-01

    We report on searching for Classical B-type emission-line (CBe) stars from the first data release (DR1) of the Large Sky Area Multi-Object fiber Spectroscopic Telescope (LAMOST; also named the Guoshoujing Telescope). A total of 192 (12 known CBes) objects were identified as CBe candidates with prominent He~I~$\\lambda4387$, He~I~$\\lambda4471$, and Mg~II~$\\lambda4481$ absorption lines, as well as H$\\beta$~$\\lambda4861$ and H$\\alpha$~$\\lambda6563$ emission lines. These candidates significantly increases current CBe sample of about 8\\%. Most of the CBe candidates are distributed at the Galactic Anti-Center due to the LAMOST observing strategy. Only two of CBes are in the star clusters with ages of 15.8 and 398~Myr, respectively.

  16. DR og musikken - en blues til 90´erne

    Directory of Open Access Journals (Sweden)

    Lars Ole Bonde

    1991-08-01

    Full Text Available Musikken i radioen er et af de mange underbelyste temaer inden for me- dieforskningen i Danmark. Forfatteren til den følgende artikel har gennem nogle år arbejdet som musik-medarbejder i Danmarks Radio - med base i Østjyllands Radio. I artiklen fokuserer han på produktionsaspektet. Hvilke funktionssammenhænge indgår musikken i inden for den kanalombrudte Danmarks Radio - både som selvstændig programform og som "akkompag- nement" til andet programstof? Dernæst følger man musikproduktionens mange former og får her afdækket både ex- og implicitte rammer for musik- politikken i institutionen. Herudfra rejses spørgsmålet om musikkens rolle i DR som aktiverende eller registrerende i forhold til det musikliv, som findes uden for institutionen.

  17. Careful monitoring of human rights needed -- Dr. Wiwat Rojanapithayakorn.

    Science.gov (United States)

    1999-12-01

    In his talk, Joint UN Program on HIV/AIDS team leader Dr. Wiwat Rojanapithayakorn made a plea for the careful monitoring of human rights with respect to the HIV/AIDS epidemic. Since the start of the HIV/AIDS pandemic, a total of 47 million people have been infected with HIV, 14 million have died of AIDS, with 33 million afflicted with the virus by the end of 1998. In the wake of this global crisis comes the widespread abuse of human rights and fundamental freedoms worldwide. Many HIV/AIDS patients suffer from discrimination, intolerance, and prejudice. Hence, protection of human rights is crucial to safeguard human dignity in the context of HIV/AIDS, and to warrant an effective public health and social responses to this epidemic. All states, regardless of their political, economic and cultural systems, have the obligation to promote and protect universal human rights standards and fundamental freedoms of all peoples.

  18. The Chymistry of "The Learned Dr Plot" (1640-96).

    Science.gov (United States)

    Roos, Anna Marie

    2014-01-01

    In the seventeenth century, there were developing norms of openness in the presentation of scientific knowledge that were at odds with traditions of secrecy among chymists, particularly practitioners of chrysopoeia, or the transmutation of metals. This chapter analyzes how Dr. Robert Plot, the first professor of chymistry at Oxford, negotiated these boundaries within an institutional context. I first delineate his chymical and experimental practice, which incorporated procedures from medieval alchemical sources, particularly the Lullian corpus, as well as more novel practices from seventeenth-century chymistry. Then, I analyze how personal and institutional ambitions and economic considerations shaped to what extent Plot negotiated the boundaries between secrecy and the public dissemination of chymical knowledge.

  19. A 10,000 YEAR OLD EXPLOSION IN DR21

    Energy Technology Data Exchange (ETDEWEB)

    Zapata, Luis A.; Perez-Goytia, Nadia; Rodriguez, Luis F.; Loinard, Laurent [Centro de Radioastronomia y Astrofisica, UNAM, Apdo. Postal 3-72 (Xangari), 58089 Morelia, Michoacan (Mexico); Schmid-Burgk, Johannes [Max-Planck-Institut fuer Radioastronomie, Auf dem Huegel 69, D-53121 Bonn (Germany); Ho, Paul T. P. [Academia Sinica Institute of Astronomy and Astrophysics, Taipei, Taiwan (China); Cruz-Gonzalez, Irene [Instituto de Astronomia, Universidad Nacional Autonoma de Mexico, Ap. 70-264, 04510 DF (Mexico)

    2013-03-10

    Sensitive high angular resolution ({approx}2'') CO(2-1) line observations made with the Submillimeter Array of the flow emanating from the high-mass star-forming region DR21 located in the Cygnus X molecular cloud are presented. These new interferometric observations indicate that this well known enigmatic outflow appears to have been produced by an explosive event that took place about 10,000 years ago, and that might be related to the disintegration of a massive stellar system such as the one that occurred in Orion Becklin-Neugebauer/Kleinman-Low 500 years ago, but about 20 times more energetic. This result therefore argues in favor of the idea that the disintegration of young stellar systems perhaps is a frequent phenomenon present during the formation of massive stars. However, many more theoretical and observational studies are still needed to confirm our hypothesis.

  20. A 10,000 Years Old Explosion in DR21

    CERN Document Server

    Zapata, Luis A; Perez-Goytia, Nadia; Ho, Paul T P; Rodriguez, Luis F; Loinard, Laurent; Cruz-Gonzalez, Irene

    2013-01-01

    Sensitive high angular resolution ($\\sim$ 2$"$) CO(2-1) line observations made with the Submillimeter Array (SMA) of the flow emanating from the high-mass star forming region DR21 located in the Cygnus X molecular cloud are presented. These new interferometric observations indicate that this well known enigmatic outflow appears to have been produced by an explosive event that took place about 10,000 years ago, and that might be related with the disintegration of a massive stellar system, as the one that occurred in Orion BN/KL 500 years ago, but about 20 times more energetic. This result therefore argues in favor of the idea that the disintegration of young stellar systems perhaps is a frequent phenomenon present during the formation of the massive stars. However, many more theoretical and observational studies are still needed to confirm our hypothesis.

  1. Biography: Dr Iain Frame, director of research, prostate cancer UK.

    Science.gov (United States)

    Frame, Iain; Maprayil, Sophia

    2014-11-01

    Sophia Maprayil, Commissioning Editor for Expert Review of Anticancer Therapy, talks to Dr Iain Frame, Director of Research for Prostate Cancer UK. Iain is Prostate Cancer UK's first Director of Research, responsible for overseeing the development and implementation of the charity's ambitious new research strategy. He joined Prostate Cancer UK in 2012 from Diabetes UK where he held the post of Research Director for 5 years. Since joining Prostate Cancer UK in 2012 Iain has overseen a dramatic increase in the charity's research spend, from 2 million a year, to 7.5 million a year. Previously Iain worked in research management at the Wellcome Trust and before that as a parasitologist and researcher exploring various aspects of molecular biology of a number of different parasites.

  2. Catalytic antibodies: balancing between Dr. Jekyll and Mr. Hyde.

    Science.gov (United States)

    Belogurov, Alexey; Kozyr, Arina; Ponomarenko, Natalia; Gabibov, Alexander

    2009-11-01

    The immunoglobulin molecule is a perfect template for the de novo generation of biocatalytic functions. Catalytic antibodies, or abzymes, obtained by the structural mimicking of enzyme active sites have been shown to catalyze numerous chemical reactions. Natural enzyme analogs for some of these reactions have not yet been found or possibly do not exist at all. Nowadays, the dramatic breakthrough in antibody engineering and expression technologies has promoted a considerable expansion of immunoglobulin's medical applications and is offering abzymes a unique chance to become a promising source of high-precision "catalytic vaccines." At the same time, the discovery of natural abzymes on the background of autoimmune disease revealed their beneficial and pathogenic roles in the disease progression. Thus, the conflicting Dr. Jekyll and Mr. Hyde protective and destructive essences of catalytic antibodies should be carefully considered in the development of therapeutic abzyme applications.

  3. Diagnostic electron microscopy and the influence of Dr. Juan Rosai.

    Science.gov (United States)

    Wick, Mark R

    2016-09-01

    Transmission electron microscopy (TEM) was introduced by Ruska and Knoll as a laboratory technique in 1933. Thereafter, several decades passed before the methods required for its optimal implementation were fully developed. Early uses of TEM were in Botany, rather than in Medicine; however, isolated publications did catalog the ultrastructural characteristics of several individual human tumor types. Finally, in 1968, Rosai and Rodriguez authored an important article, introducing the concept that TEM could be used for the differential diagnosis of histologically similar neoplasms. This publication heralded the steadily increasing application of TEM in anatomic pathology over the following decade, including continuing contributions by Dr. Juan Rosai. This brief review summarizes his influence on clinical electron microscopy, and lists some of the lesions for which that procedure is still a useful means of analysis.

  4. PERDARAHAN INTRAKRANIAL PADA BAYI DI RUMAH SAKIT DR. M. DJAMIL

    Directory of Open Access Journals (Sweden)

    Amirah Zatil Izzah

    2008-05-01

    Full Text Available AbstrakPemberian profilaksis vitamin K pada bayi baru lahir di Indonesia belum rutin dilakukan. Hampir 2/3 dari bayi dengan perdarahan akibat defisiensi vitamin K mengalami perdarahan intrakranial. Di RS DR. M. Djamil Padang belum ada profil perdarahan intrakranial pada bayi yang dirawat. Untuk melihat profil klinis bayi yang mengalami perdarahan intrakranial yang dirawat di bangsal Anak RS DR. M. Djamil Padang, data bayi berusia lebih dari tujuh hari dengan perdarahan intrakranial yang yang dirawat dari tahun 2004-2007 dikumpulkan dan ditelaah secara retrospektif. Perdarahan intrakranial dipastikan berdasarkan hasil CT scan. Di samping itu dicatat juga umur, jenis kelamin, riwayat persalinan, jenis susu yang dikonsumsi, manifestasi klinis, data hematologi, jenis perdarahan, riwayat pemberian vitamin K, dan status ketika pulang. Dari 15 bayi yang diteliti, 11 (73,3% adalah laki-laki, dan mayoritas (80% berusia antara 4-8 minggu. Empat (26,7% bayi lahir di rumah sakit, dan bidan merupakan penolong persalinan terbanyak (73,3%. Vitamin K tidak diberikan pada semua bayi saat lahir, sedangkan ASI diberikan pada 14 (93,3% bayi. Gejala yang sering dikeluhkan adalah kejang (86,7%, pucat (80% dan muntah (73,3%. Ubun-ubun besar yang tegang dan membonjol terdapat pada 86,7% bayi. Jenis perdarahan paling banyak adalah ganda (46,7%, dan tiga (20% bayi meninggal dalam perawatan. Sebagai kesimpulan, perdarahan intrakranial sering ditemukan pada bayi laki-laki berusia antara 4–8 minggu, dengan perdarahan ganda paling banyak ditemukan. Vitamin K tidak diberikan pada semua bayi termasuk bayi yang lahir di rumah sakit. Sangat perlu untuk mensosialisasikan tentang pentingnya pemberian vitamin K pada semua bayi baru lahir untuk mencegah terjadinya perdarahan intrakranial.Kata kunci: perdarahan intrakranial, defisiensi vitamin K, bayiAbstractVitamin K prophylaxis of the newborn has not been routinely administered in Indonesia. Almost two third of late hemorrhage in

  5. Prof dr FJ van Zyl as mens, kerkman en godsdiensfilosoof

    Directory of Open Access Journals (Sweden)

    P. J. van der Merwe

    1989-01-01

    Full Text Available Prof Dr FJ van Zyl as person, church personality and philosopher of religion Professor Francois Jacobus van Zyl (1913-05-06 - served as Head of the Department of Science of Religion and Missiology, Faculty of Theology (Section: Nederduitsch Hervormde Kerk, University of Pretoria, during the period 1960-1978. This article (written by a former student of his and present Head of the same Department contains a short biography, a discussion of his views on Theology, Science of Religion and Philosophy of Religion, and a bibliography. He is portrayed as a theologian with Barthian convictions, while been influenced by Emil Brunner and to a lesser extent by Hendrik Kraemer also. His primary audience was the Nederduitsch Hervormde Kerk and his theological activities (especially in the period 1960-1983 must be seen in relation to his influential role in same church.

  6. The agrobotanical garden of the Agronomy Institute "Dr. Petru Groza"

    Directory of Open Access Journals (Sweden)

    I. MOLDOVAN

    1979-08-01

    Full Text Available The paper presents the main orientations in the activities of the Agrobotanical Garden from the Agronomy Institute "Dr. Petru Groza" Cluj-Napoca, founded 75 years ago. The first period of the garden was characterised by increased interest for medicinal plants, the second for plant taxonomy and systematics, the third by ecological orientations, research on cultivated varieties and for germplasm resources. The living plant collection of the garden are presented periodically in the Index Seminum Horti Agrobotanici Cluj - Napoca published since 1962, the results of botanical interest related to research on spontaneous species and cultivated plants are published in Notulae Botanicae Horti Agrobotanici Cluj-Napoca. As a result of the research activities a Herbarium of more than 31 000 cultivated and spontaneous plant specimens are preserved.

  7. GPS/DR Error Estimation for Autonomous Vehicle Localization

    Directory of Open Access Journals (Sweden)

    Byung-Hyun Lee

    2015-08-01

    Full Text Available Autonomous vehicles require highly reliable navigation capabilities. For example, a lane-following method cannot be applied in an intersection without lanes, and since typical lane detection is performed using a straight-line model, errors can occur when the lateral distance is estimated in curved sections due to a model mismatch. Therefore, this paper proposes a localization method that uses GPS/DR error estimation based on a lane detection method with curved lane models, stop line detection, and curve matching in order to improve the performance during waypoint following procedures. The advantage of using the proposed method is that position information can be provided for autonomous driving through intersections, in sections with sharp curves, and in curved sections following a straight section. The proposed method was applied in autonomous vehicles at an experimental site to evaluate its performance, and the results indicate that the positioning achieved accuracy at the sub-meter level.

  8. Dr Goodpasture: "I was not aware of such a connection between lung and kidney disease".

    Science.gov (United States)

    Collins, Robert D

    2010-06-01

    This article describes how Dr Ernest Goodpasture's 1919 study of influenza became the basis for his name being attached to pulmonary-renal syndromes by Stanton and Tange in 1958. Dr Goodpasture was an unwilling participant in this naming, and in retrospect, the patient he described who served as the prototypic case probably had a vasculitic syndrome. Finally, Dr Goodpasture's major contributions to virology are summarized.

  9. 柯达DR3000型DR的质量保障%Failure analysis of Kodak DR3000

    Institute of Scientific and Technical Information of China (English)

    黄超; 郭磊

    2012-01-01

    解析柯达DR3000的常见故障:①因电位器故障引起U臂上下运动时报错"E08"和"E11";②SID方向移动报错"E10"和"E13";③控制电缆折断导致U臂的某方向运动失灵;④固定U臂导轨的螺丝被切断引起安全隐患的问题;⑤UPS后端的电源插头松动导致设备无法正常开机;⑥操作台和探测器上的急停开关被按下导致电源柜后端的空气开关跳闸等故障。通过分析故障原因,找到排除故障的方法,为该设备的维护保养提供方便,同时为使用科室节约维修成本,提高经济效益和社会效益。%The author discusses the following common failure of Kodak DR3000: reports of error E08 and Ell when U-arm moving up and down because of potentiometer failure; reports of error El0 and E13 when SID moves; U-arm out of control in some direction because of the fracture of control cable; the screws which are used to fix the U-arm rails are cut off, leading to some safety problems, or it would, The looseness of the power plug in the back of UPS leads to the device's failure to switch on; the emergency switch of the console and detector being pressed down leads to the air switch tripping at the back of the power supply cabinet. By analyzing the reasons of the failure and finding out the way to remove the failure, the author attempts to provide a convenient way for the maintenance of Kodak DR3000, and savc the costs of the maintenance and improve economic and social benefits as well.

  10. Inhibiting angiogenesis: interview with Dr Jean Plouët. Interview by Emma Quigley.

    Science.gov (United States)

    Plouët, Jean

    2006-08-01

    Dr Jean Plouët (Centre de Recherche Cardiovasculaire, INSERM U 689/Institut des Vaisseaux et du Sang) was interviewed by Emma Quigley (Commissioning Editor, Expert Opinion) on 20th June 2006. Born in Brittany, France, Dr Jean Plouët received his MD degree from Nantes University in 1977 and his PhD in Molecular Biology from Paris VII University in 1981. His first research topic, under the supervision of Dr Courtois and Dr Barritault was devoted to the purification and the description of the mechanisms of action of eye-derived growth factor, which turned out to be the retinal fibroblast growth factor (FGF)-2. He was appointed as Charge de Recherche by the Centre National de la Recherche Scientifique in 1981. He later conducted his research on the effect of FGF-2 on light transduction and demonstrated the role of opsin phosphorylation on FGF-2 release from retinal discs in Dr Pouliquen's laboratory. From 1987 to 1989, Dr Plouët worked in the Cancer Research Institute at the University of California, San Francisco, in Dr Gospodarowicz's laboratory where he co-discovered vascular endothelial growth factor (VEGF) with Dr Napoleone Ferrara. He established his own group in Toulouse where he worked on the mechanisms of action of VEGF and vascular targeting by anti-idiotypoc antibodies against VEGF and FGF. In 2005, Dr Plouët moved to Paris where he now works mainly on endogenous inhibitors of angiogenesis acting downstream of VEGF.

  11. Characteristics of dr1790 disruptant and its functional analysis in Deinococcus radiodurans

    Directory of Open Access Journals (Sweden)

    Jianhui Cheng

    2015-06-01

    Full Text Available Deinococcus radiodurans (DR is an extremophile that is well known for its resistance to radiation, oxidants and desiccation. The gene dr1790 of D. radiodurans was predicted to encode a yellow-related protein. The primary objective of the present study was to characterize the biological function of the DR1790 protein, which is a member of the ancient yellow/major royal jelly (MRJ protein family, in prokaryotes. Fluorescence labeling demonstrated that the yellow-related protein encoded by dr1790 is a membrane protein. The deletion of the dr1790 gene decreased the cell growth rate and sensitivity to hydrogen peroxide and radiation and increased the membrane permeability of D. radiodurans. Transcript profiling by microarray and RT-PCR analyses of the dr1790 deletion mutant suggested that some genes that are involved in protein secretion and transport were strongly suppressed, while other genes that are involved in protein quality control, such as chaperones and proteases, were induced. In addition, the expression of genes with predicted functions that are involved in antioxidant systems, electron transport, and energy metabolism was significantly altered through the disruption of dr1790. Moreover, the results of proteomic analyses using 2-DE and MS also demonstrated that DR1790 contributed to D. radiodurans survival. Taken together, these results indicate that the DR1790 protein from the ancient yellow protein family plays a pleiotropic role in the survival of prokaryotic cells and contributes to the extraordinary resistance of D. radiodurans against oxidative and radiation stresses.

  12. Dr. House: Patología Dual en el Médico

    OpenAIRE

    Bellina, Mariano A.; Braquehais, Maria Dolores

    2012-01-01

    [ES] Dr. House es una serie dramática estadounidense cuyo personaje central es el Dr. Gregory House, médico que dirige una unidad de diagnóstico (con otros tres doctores) en el Hospital Universitario Princeton‐ Plainsboro, en Nueva Jersey. Dr. House utiliza un proceso lógico especial como base para llegar al diagnóstico. La Unidad que dirige el Dr. House trata pacientes que han sido evaluados previamente por otros doctores sin haber alcanzado un diagnóstico. Los diagnósticos oscil...

  13. [A new approach to accelerate DR image enhancement based on CUDA].

    Science.gov (United States)

    Xiangbin, He; Heqin, Zhou; Fangyong, Li

    2010-01-01

    Multiscale pyramid image enhancement algorithm is an usual way to enhance the Digital Radiography (DR) images. However, the process of enhancement takes much of time because of the fine resolution of DR images. A new method of accelerating DR image enhancement based on Compute Unified Device Architecture (CUDA) is presented in this paper. This method completes a large amount of convolution operations in spatial domain involved in the multiscale pyramid image enhancement algorithm by using the Graphic Processing Unit (GPU). The experimental results show that the proposed method is very efficient for accelerating DR image enhancement.

  14. Safety evaluation for packaging for 1720-DR sodium-filled tank

    Energy Technology Data Exchange (ETDEWEB)

    Mercado, M.S.

    1996-03-09

    Preparations are under way to sell the sodium stored in the 1720-DR tank in the 1720-DR building. This will require that the tank, as well as the 1720-DR facility, be moved to the 300 Area, so that the sodium may be melted and transferred into a railroad tanker car. Because the sodium is a hazardous material and is being shipped in a nonspecification packaging, a safety evaluation for packaging (SEP) is required. This SEP approves the sodium-filled tank for a single shipment from the 105-DR area to the 300 Area.

  15. Pioneers of Study on Desorption Induced by Electronic Transitions; Achievements by Dr. Yoshioki Ishikawa and Dr. Yoshio Ohta

    Science.gov (United States)

    Mase, Kazuhiko; Nambu, Akira

    Dr. Yoshioki Ishikawa is a pioneer who carried out systematic electron stimulated desorption (ESD) investigations for hydrogen adsorbed on a clean platinum plate (H2/Pt) under ultrahigh vacuum (UHV) conditions in 1942. (His name is spelled as Yosioki Isikawa in the original papers.) Although his papers are referred in several papers on desorption induced by electronic transitions (DIET), these seem to be not as well-known as famous ones by Menzel, Gomer, and Redhead in 1964. We describe his pioneering work in this article. He developed an UHV apparatus made of glass with a Pt plate and an oxide cathode pumped by a small mercury pump via a liquid air trap. Clear ESD signals were observed for H2/Pt at excitation energies of 8, 12, 14, 33-46, and 46-51 eV. He assigned the desorbate to atomic hydrogen (H), because it was pumped by a glass wall baked above 350°C. Based on these results and the potential curves of H2 in the gas phase, he proposed a model for the ESD of H from H2/Pt that is, the first step is an electronic transition of adsorbed H2, and the second is the desorption of H along the repulsive potential surface of the excited state. This was the first introduction of the notion of DIET. He also carried out an ESD study of H2O/Pt in 1943. We also introduce achievements by Dr. Yoshio Ohta, who was another pioneer in the field of DIET. He measured electron-stimulated ion desorption from an oxidized Ni plate. He found that the threshold excitation energy for ion desorption is 22 eV, and that the kinetic energy of the desorbed ion is 1˜2 eV. To explain these results, he also proposed the concept of DIET.

  16. Jürgen Dröge : Eestimaa lilled panevad südame põksuma / Jürgen Dröge ; interv. Annika Poldre

    Index Scriptorium Estoniae

    Dröge, Jürgen, 1941-

    2005-01-01

    Ametist lahkuv Saksamaa Liitvabariigi suursaadik Eestis Jürgen Dröge oma karjäärist välisteenistuses, Eestist saadud muljetest, Saksamaa ja Venemaa suhetest, Balti riikide arengust Euroopa Liidus

  17. Differential recognition of members of the carcinoembryonic antigen family by Afa/Dr adhesins of diffusely adhering Escherichia coli (Afa/Dr DAEC).

    Science.gov (United States)

    Berger, Cedric N; Billker, Oliver; Meyer, Thomas F; Servin, Alain L; Kansau, Imad

    2004-05-01

    Little is known about the molecular bases underlying the virulence of diffusely adhering Escherichia coli (DAEC) harbouring the Afa/Dr family of adhesins. These adhesins recognize as receptors the GPI-anchored proteins CD55 (decay-accelerating factor, DAF) and CD66e (carcinoembryonic antigen, CEA). CD66e is a member of the CEA-related cell adhesion molecules (CEACAM) family, comprising seven members. We analysed the interactions of Afa/Dr DAEC with the CEACAMs using CEACAM-expressing CHO and HeLa cells. The results demonstrate that only E. coli expressing a subfamily of Afa/Dr adhesins, named here Afa/Dr-I, including Dr, F1845 and AfaE-III adhesins, bound onto CHO cells expressing CEACAM1, CEA or CEACAM6. Whereas all the Afa/Dr adhesins elicit recruitment of CD55 around adhering bacteria, only the Afa/Dr-I subfamily elicits the recruitment of CEACAM1, CEA and CEACAM6. In addition, although CEACAM3 is not recognized as a receptor by the subfamily of Afa/Dr adhesins, it is recruited around bacteria in HeLa cells. The recruited CEACAM1, CEA and CEACAM6 around adhering bacteria resist totally or in part a detergent extraction, whereas the recruited CEACAM3 does not. Finally, the results show that recognition of CEA and CEACAM6, but not CEACAM1, is accompanied by tight attachment to bacteria of cell surface microvilli-like extensions, which are elongated. Moreover, recognition of CEA is accompanied by an activation of the Rho GTPase Cdc42 and by a phosphorylation of ERM, which in turn elicit the observed cell surface microvilli-like extensions.

  18. Star Formation in the DR21 Region (A)

    Science.gov (United States)

    2004-01-01

    [figure removed for brevity, see original site] Annotated mosaic Hidden behind a shroud of dust in the constellation Cygnus is a stellar nursery called DR21, which is giving birth to some of the most massive stars in our galaxy. Visible light images reveal no trace of this interstellar cauldron because of heavy dust obscuration. In fact, visible light is attenuated in DR21 by a factor of more than 10,000,000,000,000,000,000,000,000,000,000,000,000,000 (ten thousand trillion heptillion). New images from NASA's Spitzer Space Telescope allow us to peek behind the cosmic veil and pinpoint one of the most massive natal stars yet seen in our Milky Way galaxy. The never-before-seen star is 100,000 times as bright as the Sun. Also revealed for the first time is a powerful outflow of hot gas emanating from this star and bursting through a giant molecular cloud. The colorful image (top panel) is a large-scale composite mosaic assembled from data collected at a variety of different wavelengths. Views at visible wavelengths appear blue, near-infrared light is depicted as green, and mid-infrared data from the InfraRed Array Camera (IRAC) aboard NASA's Spitzer Space Telescope is portrayed as red. The result is a contrast between structures seen in visible light (blue) and those observed in the infrared (yellow and red). A quick glance shows that most of the action in this image is revealed to the unique eyes of Spitzer. The image covers an area about two times that of a full moon. Each of the constituent images is shown below the large mosaic. The Digital Sky Survey (DSS) image (lower left) provides a familiar view of deep space, with stars scattered around a dark field. The reddish hue is from gas heated by foreground stars in this region. This fluorescence fades away in the near-infrared Two-Micron All-Sky Survey (2MASS) image (lower center), but other features start to appear through the obscuring clouds of dust, now increasingly transparent. Many more stars are discerned in

  19. [WHO AFFECTS THE PATIENT, DR. GOOGLE OR THE DOCTOR?].

    Science.gov (United States)

    Mishali, Moshe; Avrech, Tova

    2015-09-01

    In the last decade the World Wide Web has become one of the prime sources for medical data searches. The abundance of information and emphasis on consumer communication, which are the main characteristics of the new generation of the web named "Web 2.0", enable users to engage and educate others by sharing and collaborating knowledge. It also enables them to receive medical information based on the experience of other patients, while the duration of the traditional physician's visit has shortened. However, using Web 2.0 for health collaboration has drawbacks as well: When alternative ways of "knowing" replace objective medical facts, there is danger of misinformation and truth "flattening". This article examines the distribution of medical misinformation online: Its characteristics, the nature of the messages presented online and the means that might help protect users and patients from it. The authors hold positions in the Israeli Dairy Board (IDB): Dr. Averch manages the health field on the IDB, and the findings in this article are based on research that she is leading as part of this position, and Dr. Mishali is a trained psychologist, and acts as a strategic consultant for IDB in the field of coping with the opposition to milk and its products. In this article it is initially shown how the characteristics of information distribution in general help spreading medical misinformation online: The decline of doctors' authority as sole providers of medical information, disillusionment and suspicion towards science and the notion of expertise, and the emergence of new ways to evaluate information, based on community ties. The nature of this pseudo-medical information will then be discussed, including the range of the phenomenon and the probability of users to be affected by it. Furthermore, we will raise specific tactics in which anti-establishment messages are portrayed; examples will be given of the use of emotion evoking content in the anti-establishment messages

  20. Dr. Mrs. Dhanalakshmi De Sousa 1938-2005: A Tribute

    Directory of Open Access Journals (Sweden)

    Avinash De Sousa

    2006-03-01

    Full Text Available It is always tough when one has to write a tribute to one's mother and tougher still when the same has to be written after her demise and when we remember her most. Yet I undertake this onerous task. Many people know her as the past Professor and Head of the Department of Psychiatry at Lokmanya Tilak Municipal Medical College and General Hospital, but it is the personal side of her personality that I wish to highlight here.Born on 3rd October 1938 and brought up in a traditional South Indian family, she lost her father at an early age when she was just 8 years old. Yet she struggled and studied hard, her efforts earning her an admission for the medical graduation course at Seth G.S. Medical College, Mumbai. She joined the Department of Psychiatry at K.E.M. Hospital in 1965 under Dr. V.N. Bagadia and said it was chance that led her to do so. Later she told me it was her destiny, as she had to meet her love and husband Dr. Alan De Sousa there.She was instrumental in starting the Child Guidance Clinic at Nair Hospital that has today risen to be one of the best in the city. She joined Sion Hospital in 1971 as a Honorary Professor and had an avid interest in teaching both post graduates and under graduate students. She worked there till 1989 when she retired as the Prof and Head of the Department. Her retirement was premature for which I take the blame. She always knew what her priorities were and gave me all the best she could. Once when I told her that she was too busy and did not have time for me, it was the very next day that she submitted her resignation from the Department. It was a courageous decision, one for which I hope I fulfill all her dreams. She had a special interest in child psychiatry, substance abuse and psychiatric problems in women. [No abstract available.

  1. The Honorable Dr Adolfo Urso, Vice Minister for Foreign Trade, "Viceministro delle Attivita' Produttive, Italia"

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    Photo 01: The Honorable Dr Adolfo Urso, Deputy Minister for Productive Activities, Italy, visiting SM18 with (from l to r): Dr Roberto Saban, Technical Coordination and Planning, LHC machine; Prof. Luciano Maiani, CERN Director-General; Dr Mario Gerbino, Director General of the Ministry and Prof. Lucio Rossi, LHC Main Magnet and Superconductors (MMS) Group Leader. Photo 02: Prof. Luciano Maiani, CERN Director-General and The Honorable Dr Adolfo Urso, Deputy Minister for Productive Activities, Italy, in front of one of the LHC superconducting magnet in SM18. Photo 03 :In front of one of the LHC superconducting magnets - from left to right Dr Roberto Saban, Technical Coordination and Planning, LHC machine; The Honorable Dr Adolfo Urso, Deputy Minister for Productive Activities, Italy and Prof. Luciano Maiani, CERN Director-General. Photo 04: In the SM18 hall (from l. to r.) Prof. Luciano Maiani, CERN Director-General, The Honorable Dr Adolfo Urso, Deputy Minister for Productive Activities, Italy and Dr Mario Ge...

  2. Genomic analysis identifies class II mismatches in serologically DR-compatible human renal allografts.

    Science.gov (United States)

    Bushell, A; Wood, K J; Morris, P J

    1988-11-01

    Many studies, including those from our own center, have shown that matching the donor and recipient for HLA-DR antigens has a beneficial effect on the outcome of cadaveric renal transplantation. However, cases of irreversible graft rejection are sometimes seen in patients who have received an HLA-DR-compatible kidney, suggesting that serologic compatibility for HLA-DR may not always ensure reduced alloreactivity toward the graft. We have examined a number of recipients and their serologically DR-compatible cadaveric donors by Southern blotting and hybridization with locus specific HLA class II probes in order to determine whether in these patients there were class II mismatches that had been undetected by serology. The results show that the analysis of DR beta restriction fragment patterns does little more than complement and confirm the serologic identification of HLA-DR. Hybridization with DQ alpha and DQ beta probes, however, significantly extends the number of DQ specificities that can be detected and suggests that DQ mismatches in DR-compatible donor-recipient pairs may be more common than previously supposed, although it is not possible to draw any conclusions on the influence of DQ incompatibilities in the presence of DR compatibility on graft outcome.

  3. Data of evolutionary structure change: 1DR8B-3DMSA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1DR8B-3DMSA 1DR8 3DMS B A --------------------------MKVAVLPGDGIGP...D>3DMS A 3DMSA AVEKAYGGKKKIH ...entryChain> 3DMS A 3DMSA TKVYGPDV...90 SER CA 526 3DMS A 3DMSA...ine>PHE CA 324 3DMS A 3DMSA

  4. 76 FR 14407 - Exchange of Letters Between Dr. Murray M. Lumpkin, Deputy Commissioner, International Programs...

    Science.gov (United States)

    2011-03-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Exchange of Letters Between Dr. Murray M. Lumpkin, Deputy... providing notice of exchange of letters between Dr. Murray M. Lumpkin, Deputy Commissioner, International...

  5. HLA-DR and -DQ gene polymorphism in Latvian patients with insulin-dependent diabetes mellitus.

    Science.gov (United States)

    Shtauvere, A; Rumba, I; Dzivite, I; Sanjeevi, C B

    1998-10-01

    Latvian insulin-dependent diabetes mellitus (IDDM) patients (n=101) and healthy controls (n=111) were analyzed for HLA-DR and DQ polymorphism. DR3-DQ2 and DR4-DQ8 were positively associated and DR15-DQ6, DR13-DQ6, DR1-DQ5 and DQ7 negatively associated with the disease. The incidence of IDDM in Latvia is very low (6.5 per 100,000) compared to Sweden (24.4 per 100,000), even though Latvia is close to Sweden. The reasons for the decreased incidence are not clear. When the negatively associated DQ were taken together in the healthy controls, more than 75% of the healthy controls were positive for one of the four negatively associated DQ molecules. The excess frequency of the negatively associated DQ molecules in the general population could explain the lower incidence of IDDM in Latvia. Association of HLA-DR and DQ genes with autoantibody markers shows DR3, but not DQ2, to be increased in GAD65 antibody-positive compared to antibody-negative patients. This association was not observed with ICA512 antibodies.

  6. Data of evolutionary structure change: 1DR8A-1ISOA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1DR8A-1ISOA 1DR8 1ISO A A ------------------------MKVAVLPGDGIGPEV...70 1ISO A 1ISO...CA 388 PHE CA 401 PRO CA 322 GLU CA 240 1ISO... A 1ISOA TQVYGQDV...VAL CA 456 VAL CA 489 SER CA 527 1ISO

  7. Dr.Shi Yanqing's Experience in Acupuncture Treatment of Paralysis Agitans

    Institute of Scientific and Technical Information of China (English)

    施孝文

    2004-01-01

    @@ Dr. Shi Yanqing (施延庆), a chief physician of traditional Chinese medicine, is an expert using warm-needling therapy to treat obstinate and miscellaneous diseases. In his long years of clinical practice, Dr. Shi has treated several tens of paralysis agitans cases, and obtained quite good therapeutic effects as is introduced in the following.

  8. The Dr Pheo Blog and virtual counselling for rare diseases.

    Science.gov (United States)

    Yu, Run

    2015-01-01

    Patients with suspected or diagnosed rare diseases face challenges. Their own physicians usually do not have a large experience in a particular rare disease, specialists may not be easily accessible, and medical knowledge on rare diseases is either not readily available or too general to be applied to the patients' individual situations. As a specialist with experience in pheochromocytoma, I therefore started a blog to disseminate knowledge about the tumour and to discuss readers' questions about it (http://drpheo.blogspot.com/). Between 2009 and 2014, the blog was viewed 81,223 times and received 1286 comments during the 5-year period. About half of the comments contained mostly questions (questioning comments), including 429 directly on pheochromocytoma (7.5/month). The majority of the questioning comments were about the diagnosis (62%) and natural history (21%) of pheochromocytoma, with the remainder on management (14%) and follow-up or prognosis (4%). Many readers' comments started with encouraging words about the blog and remarked how difficult it was to find useful information on pheochromocytoma elsewhere. Experience with the Dr Pheo Blog suggests that physician specialist-written blogs are potentially an effective and convenient way of providing pertinent knowledge on rare diseases to the public. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  9. Limitation of Multipoles in BOSS DR12 results

    CERN Document Server

    Lee, Seokcheon

    2016-01-01

    Recently, the power spectrum (PS) multipoles using the Baryon Oscillation Spectroscopic Survey (BOSS) Data Release 12 (DR12) sample are analyzed \\cite{160703150}. Even though the based model for the analysis is the so-called TNS quasi-linear model including the multipole up to the eighth order in the window function \\cite{TNS}, the analysis provides the multipoles up to the hexadecapole. Thus, one might be able to recover the galaxy PS by using the combination of multipoles to investigate the cosmology \\cite{0407214}. We provide the analytic form of this combination of multipoles of the quasi-linear PS including the Fingers of God (FoG) effect to recover the PS at the linear regime. In order to confirm the consistency of the multipole data, we compare the multipole ratios of the linear theory including the FoG effect with those of observation. The data of the ratio of quadrupole to monopole is consistent with that of the linear theory prediction even though the current observational error is too large to dist...

  10. Dr. Monaco Examines Lab-on a-Chip

    Science.gov (United States)

    2003-01-01

    Dr. Lisa Monaco, Marshall Space Flight Center's (MSFC's) project scientist for the Lab-on-a-Chip Applications Development (LOCAD) program, examines a lab on a chip. The small dots are actually ports where fluids and chemicals can be mixed or samples can be collected for testing. Tiny channels, only clearly visible under a microscope, form pathways between the ports. Many chemical and biological processes, previously conducted on large pieces of laboratory equipment, can now be performed on these small glass or plastic plates. Monaco and other researchers at MSFC in Huntsville, Alabama, are customizing the chips to be used for many space applications, such as monitoring microbes inside spacecraft and detecting life on other planets. The portable, handheld Lab-on-a Chip Application Development Portable Test System (LOCAD-PTS) made its debut flight aboard Discovery during the STS-116 mission launched December 9, 2006. The system allowed crew members to monitor their environment for problematic contaminants such as yeast, mold, and even E.coli, and salmonella. Once LOCAD-PTS reached the International Space Station (ISS), the Marshall team continued to manage the experiment, monitoring the study from a console in the Payload Operations Center at MSFC. The results of these studies will help NASA researchers refine the technology for future Moon and Mars missions. (NASA/MSFC/D.Stoffer)

  11. [Life and work of Dr. Jovan Jovanović Zmaj].

    Science.gov (United States)

    Lesić, Aleksandar; Bumbasirević, Marko; Zizić-Borjanović, Slavica

    2006-10-01

    The year of 2004 was the 100th anniversary of death of the poet and physician Dr. Jovan Jovanović Zmaj. Jovan Jovanović Zmaj was born in 1833 in Novi Sad, and died in 1904 in Sremska Kamenica J.J. Zmaj himself studied law and worked in the Novi Sad magistrate court. It was not until he turned 30 that he began practicing medicine. He developed as a poet as early as during his studies. He remained loyal to the vocations of physician and poet throughout his life. He wrote over 5000 poems, ranging from those for children through those for adults and those with which he addressed the rulers satirically. He was a founder of a number of magazines (Javor, Neven, Komarac, Danica). At that time of Romanticism, the work of J.J. Zmaj also had a national character. However, he succeeded in achieving something more: he introduced a literary genre till then unknown in Serb literature--literature for children. Through his genre he promoted not only Serbian language but also hygiene, by which he played a significant health care role, similar to that played by his friend Milan Jovanović Batut, only from a different aspect. He also used to draw, and his drawing of the emblem of the Serbian Literary Association has remained on the cover of every book published by it until these days.

  12. Intussusception at the pediatric ward of Dr. Pirngadi Hospital, Medan.

    Science.gov (United States)

    Lubis, A H; Sinuhaji, A B; Sutanto, A H; Yosodiharjo, A

    1990-01-01

    A retrospective study had been conducted on hospitalized infants and children in the Pediatric ward of Dr. Pirngadi Hospital, Medan from January 1, 1987 through December 31, 1988. The purpose is to assess the incidence and clinical manifestations of intussusception. During the same period, there were 6484 infants and children hospitalized, 39 (0.6%) with intussusception, consisting of 23 (58.9%) males and (41.1%) females. Most of the cases (53.85%) were in age group of 4-6 months. Thirty four patients (87.12%) were wellnourished, and 5 patients (12.82%) undernourished. The major symptoms of intussusception were bloody diarrhoea (87.17%), vomiting (82.05%) and abdominal distention (66.41%). Successful reposition with barium enema occurred in 1 (20%) out of 5 patients. The major symptoms of intussusception were bloody diarrhoea (87.17%), vomiting. Surgical intervention was performed in 22 patients (56.41%). The result was as follows: discharged in good condition in 15 (68.18%) and deaths occurred in the remaining cases (7 cases = 31.82%). Of those 7 cases who died after operation, 2 cases were hospitalized in less than 2 days, 3 cases in less than 3 days and the remaining 2 cases in more than 3 days, after the symptoms developed.

  13. ¿Quién es el Dr. Alvarado?

    Directory of Open Access Journals (Sweden)

    Arturo Jauretche

    2012-01-01

    1955, el Dr. Alvarado es separado de su cargo por la Revolución Libertadora, momento en que la Organización Panamericana de la Salud lo designa asesor regional y entre 1959 y 1964 lo nombran jefe del programa de erradicación de la malaria de la Organización Mundial de la Salud, en Ginebra, Suiza. A su regreso al país en 1966, organiza el Plan de Salud Rural, creando para ello la figura del "agente sanitario" y la "ronda sanitaria" anticipándose a conceptos que varios años después se plasmarían en la Atención Primaria de la Salud. El texto de Jauretche fue publicado originalmente en 1967 en el libro Los profetas del odio, por la editorial de Arturo Peña Lillo, editor de los grandes títulos del "pensamiento nacional" argentino. Su reedición en la sección "Memoria e historia" es un modo de rendir homenaje a una de las figuras indiscutibles de la Salud Pública argentina.

  14. INPATIENTS NUTRITIONAL REQUIREMENTS INDICATOR AT ARMY HOSPITAL DR. SOEPRAOEN MALANG

    Directory of Open Access Journals (Sweden)

    Kumboyono Kumboyono

    2017-04-01

    Full Text Available Introduction: Patient acceptance to diet in fl uences patient intake during the hospitalization. Patient acceptance on meals provided by the hospital can be seen from the left over. Whilst factors which in fl uences patient motivation to finish their meals including addtional food, taste, and adaptation level to the hospital, the aim of this research was to identify factors that related to patient acceptance on meals provided by the hospital in class three ward dr. Soepraoen Hospital, Malang. Method: Descriptive analitic was used as research design with cross-sectional approach. As many as 51 samples were chosen with purposive sampling. Data was analyzed with chi square with 95%signi fi cance. Results: The results showed a signi fi cant relation between additional food and the leftover (p-Value = 0,018. There is signi fi cant relation on the taste and the leftover (p-Value = 0.032 and adaptation level and leftover (p-Value = 0.026. Discussion: It can be concluded that additional food, taste, and adaptation level to the hospital have signi fi cant relation with hospitalized patient acceptance on their diet. It is suggested that nurse pay more attention on these factors to fulfi ll patient nutrition needs during hospitalization.

  15. 2015 AMCA Memorial Lecture Honoree: Dr. Richard Floyd Darsie, Jr.

    Science.gov (United States)

    Day, Jonathan F

    2015-12-01

    Richard Floyd Darsie, Jr. (1915-2014) is the 2015 American Mosquito Control Association Memorial Lecture Honoree. He was one of the greatest mosquito taxonomists of the 20th century and died peacefully on April 10, 2014, in Grove City, PA, at the age of 99 after a professional career that spanned eight decades. Dick's broad areas of interest and training made him a versatile scientist, teacher, and researcher. His intense interest in adult and immature mosquito morphology and taxonomy, as well as mosquito distribution and bionomics, started early in his career at two early academic postings: Franklin and Marshall College (1949-54) and the University of Delaware (1954-62). Dick would take his mosquito interests with him to postings and research projects around the world: Nepal, the Philippines, Atlanta, El Salvador, Guatemala, Fort Collins, South Carolina, Argentina, and Florida. His travels and studies would make him an international expert on mosquito taxonomy. Dick's legacy lives on in the hundreds of students from across the globe who learned mosquito identification skills from this world-renowned mosquito taxonomist. All will proudly profess that, "I learned mosquito identification from Dr. Darsie." And that is all that is needed to prove one's credentials in the field, learning the art from the best there is.

  16. The life-work of Prof. MUDr. Zdenek Lojda, Dr.Sc., Dr. Med. et Iur. h.c.

    Science.gov (United States)

    Hach, P

    2008-01-01

    Professor Zdenek Lojda, MD., Dr.Sc., Dr. Med.h.c., Dr. Jur. h.c., vice-rector emeritus of the Charles University and director emeritus of the Institute of Histology and Embryology of the 1st Medical Faculty of the Charles University in Prague died on the 24th April 2004. Born in Trebíc (in a local maternal hospital on the 7th December 1927) he grew up in Moravské Budejovice where he graduated from a primary and secondary school (he passed out each class as well as the leaving exam at the local gymnasium in 1946 cum laude). He was growing up in an inspiring atmosphere of a family of a professor at gymnasium that helped him to form his fundamental moral attitude and to gain high knowledge of an almost Renaissance comprehension. He was a gifted linguist (he spoke fluently several languages including Latin) and musician (he did community singing among others) and he was interested in natural sciences. In 1946 he enrolled for the medical faculty and coincidentally he was grouped among students that completed histology and embryology at the Institute of Embryology headed by professor Zdenek Frankenberger, MD., who had recognised his interest in this field of study. The young student gave himself and his free time to the work of an unqualified lab-worker and only later he became assistant conducting practical tutorials. He took his degree cum laude in 1952 and he received certificate of competence because of his excellent results. He showed his preoccupation with histology (strongly influenced by the personality of professor Frankenberger) after the graduation when he entered the job of the assistant professor at the Institute of Embryology and he stayed there until 1961. When he was about to decide which problems he should target, professor Frankenberger drew his attention to a very interesting part of histology that was just in advance and that was the use of diazonic salts for formation of colour reaction product demonstrating enzyme activity in tissues. In 1962

  17. [Dr Guillermo Contreras Da Silva, a relevant figure in the development of Chilean microbiology].

    Science.gov (United States)

    Cabello, Felipe C

    2008-02-01

    The influence of the work of Dr. Guillermo Contreras Da Silva and his colaborators on the evolution of microbiology in Chile is briefly analyzed. Dr. Contreras was trained in modern virology at Yale University with Dr. J. Melnick under the sponsorhip of the Rockefeller Foundation. During this training, he used serological methods to classify Cocksakie viruses. After his return to Chile, he studied the epidemiology of enteroviruses, including poliovirus. His laboratory, the country's first in modern virology, took an active role in Chile's first Sabin polio vaccination in 1961. Dr. Contreras and his group transformed the teaching and the character of microbiology in Chile from a descriptive medically oriented discipline into an autonomous, quantitative and experimental science. They modernized microbiology with the introduction of molecular biology and microbial genetics and fostered collaborations with allied biological sciences. Dr. Contreras was a Guggenheim Fellow, and until his retirement, was the Chief of the Viral Products Division, Bureau of Biologies, Ottawa, Canada.

  18. Dröm i film : En innehållsanalys av drömsekvenser från tre olika filmer utgående från Thorsten Botz-Bornsteins drömteorier

    OpenAIRE

    Knorring, Markus von

    2012-01-01

    Mitt examensarbete är en kvalitativ innehållsanalys av drömsekvenser från filmerna Smultronstället (1957) av Ingmar Bergman, Shutter Island (2010) av Martin Scorsese samt min egen film Red (2010). Grunden för analysen är Thorsten Botz-Bornsteins bok Films and dreams, där han presenterar tio nyckelord som beskriver särdrag för dröm i film. Tre av dessa nyckelord utgör basen och den teoretiska ramen för mitt arbete. Nyckelorden är surrealism, drömfärger och det obehagliga. Syftet med arbetet är...

  19. Prof Dr Zeki Soysal’a Saygi ile

    Directory of Open Access Journals (Sweden)

    Sermet Koç

    2006-12-01

    Full Text Available Dr. Sermet KOÇ Zeki Hoca’mızın kim olduğunu, neler yapıp; neler bıraktığını anlatmayacağım, gerek te yok, çoğumuz biliyor. Ama bilmeyenler var ise, internette bir tuşla öğrenebilirler. Seni yitirmemizin üzerinden aylar geçti, yokluğuna alışamadık Zeki Hocam! Her gün anabilim dalının kapısından girince sanki birden yine karşılaşacağımızı ve o içten ‘abi’ sesinle yine “Günaydın, nasılsın Sermet?" diye sesleneceğini sanıyorum. Sadece ben mi? Bu her gün küçülen çatımızda çalışmaya devam eden diğer arkadaşların da, eminim aynı hisse sık sık kapılmaktalar. Onun kapısı, tabir caiz ise, gerçek bir “Mevlana kapısı" idi. Bu kapının konuğu hiç eksik olmazdı ve Zeki Ahi’miz her defasında herkesi ayakta aynı içtenlikle karşılar, uzun uzun sohbet etmek, sorunlarını paylaşmak isterdi. Odasında, masalar üzerinde elle yazılmış veya bilgisayar çıktısı rulo rulo kağıtlardan; onun yeni bir kitap üzerinde çalıştığını anlamak hiç de zor olmazdı ve her çalışmasına bir çok kişiyi ortak etmeyi (çoğu kez gerekmese de bir hoca olarak görevi gibi kabul ederdi. Yine arka odasındaki sürekli kaynayan çaydanlığın sesi ve tezgahta dizili çay ve kahve bardakları, o gün gelecek konuklarını beklerdi. Şimdi bize, Adli Tıbbın mazisi ile ilgili sıra dışı anılar, öyküler anlatacak pek de kimse kalmadı. Zeki Hoca’nın Adli Tıptaki ilk yılları.. Şemsi Hoca ile bir kaç doktor ve teknisyen ile akşamlara kadar yapılan otopsiler; gecelere kadar yapılan dosyalar ve sonrasında kurulan sofralar; daha sonra araya giren Malta günleri, Kadın-Doğum Kliniği’nde geçen asistanlık yılları; sonra tekrar yuvaya dönüş,.. öğrenci, asistan ve mesai arkadaşları ile paylaşılan sayısız anı. Hastalığının birkaç yıl öncesinde çok sevdiği kızı ve eşi ile birlikte Şile’de yazlık almışlardı da; ama o yine tatilinin

  20. Signature in the microcosm with Professor Bas S.C.J.J. Kortmann, Rector Magnificus Dr Anton A.J.M. Franken, Vice President Radboud University Nijmegen Kingdom of the Netherlands and Dr. Jos Engelen, Chief Scientific Officer of CERN.

    CERN Multimedia

    Maximilien Brice

    2008-01-01

    Signature in the microcosm with Professor Bas S.C.J.J. Kortmann, Rector Magnificus Dr Anton A.J.M. Franken, Vice President Radboud University Nijmegen Kingdom of the Netherlands and Dr. Jos Engelen, Chief Scientific Officer of CERN.

  1. Monocyte human leukocyte antigen-DR transcriptional downregulation by cortisol during septic shock.

    Science.gov (United States)

    Le Tulzo, Yves; Pangault, Celine; Amiot, Laurence; Guilloux, Valérie; Tribut, Olivier; Arvieux, Cédric; Camus, Christophe; Fauchet, Renée; Thomas, Rémi; Drénou, Bernard

    2004-05-15

    Monocyte deactivation has been identified as a major factor of immunosuppression in sepsis and is associated with a loss of surface human leukocyte antigen-DR (HLA-DR) expression on circulating monocytes. Using flow cytometry, quantitative reverse transcription-polymerase chain reaction, we investigated this phenomenon in septic patients. We confirmed the early loss of monocyte HLA-DR expression in all infected patients and demonstrated that this persistent lowered expression at Day 6 correlated with severity scores, secondary infection, and death. This phenomenon occurred at a transcriptional level via a decrease in the class II transactivator A (CIITA) transcription. Furthermore, these abnormalities correlated with the high cortisol levels observed in sepsis and not with those of other putative factors such as catecholamines or interleukin-10. Finally, in vitro studies evidenced that glucocorticoids decrease HLA-DR expression at a transcriptional level via a decrease in CIITA mRNA levels, mainly by down modulating its isoforms I and III. We conclude that in human sepsis, the loss of HLA-DR expression on circulating monocytes is associated with a poor outcome. We suggest that the high endogenous cortisol level observed in septic shock may be a possible new factor involved in the loss of HLA-DR expression on monocytes via its effect on HLA-DR and CIITA transcription.

  2. Then & Now: Research Pays Off for All Americans / Dr. Virginia Apgar: Keeping Score at Baby's First Cry | NIH ...

    Science.gov (United States)

    ... Research Pays Off for All Americans Dr. Virginia Apgar: Keeping Score at Baby's First Cry Past Issues / Winter 2010 ... evaluated your physical condition and gave you an Apgar score. The score is named for Dr. Virginia Apgar ( ...

  3. Dr Fijiwara, Head of the Internet research Institute, Mr Ogino, Executive and Head of Ubiquitous Lab of IRI, Japan

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Japanese delegation from the Internet Research Institute visiting the ATLAS assembly hall in building 180 with Dr. Akira Yamaguchi, KEK laboratory, ATLAS experiment (first from left) and Dr. Masaya Ishino, University of Tokyo, ATLAS experiment (third from left).

  4. European Insecurity: Managing Changing Relations at Home and Abroad : Interviews with Dr. Margriet Drent and Dr. Bibi van Ginkel of the Security and Conflict Programme of the Netherlands Institute of International Relations ‘Clingendael’

    NARCIS (Netherlands)

    Fraser, J.A.

    2012-01-01

    Interviews with Dr. Margriet Drent and Dr. Bibi van Ginkel of the Security and Conflict Programme of the Netherlands Institute of International Relations 'Clingendael' Dr. Margriet Drent is a Senior Research Fellow at the Security and Conflict Programme of the Netherlands Institute of International

  5. Dr. Buchel,The Pad Printing world will miss You forever!%Dr.Buchel, 整个移印行业会永远记得您!

    Institute of Scientific and Technical Information of China (English)

    何宏文

    2008-01-01

    @@ 2008年10月15日,坚毅公司同德国Wiederhold油墨公司现任CEO——Mr.Baumhoer一起在Kent的高要工厂为Dr,Buchel举行了欢送晚宴.对所有同Dr,Buchel共过事的人来说.那都是一个感觉复杂的时刻:一方面,我们有点难过,因为从此之后,我们将不再有机会在移印行业中见到Dr,Buchel的身影;但另一方面,我们也非常开心.因为他终于可以卸下他长期以及一生所从事的移印工作.

  6. Study on the thermo-optic properties of DR1/PMMA composite

    Institute of Scientific and Technical Information of China (English)

    Li Xiang; Cao Zhuang-Qi; Shen Qi-Shun; Yang Yan-Fang

    2006-01-01

    This paper reports that the thermo-optic coefficient (dn/dT) as well as thermal expansion coefficients (β) of DR1/PMMA polymer film are measured for both TE (transversal electric) and TM (transversal magnetic) polarizations by using an attenuated total reflection configuration at the wavelengths of 832nm. The thermo-optic coefficients of DR1/PMMA are negative and as high as the order of 10-4/°C. The influences of dopant concentration, poling process and photobleaching process on the thermo-optic properties of DR1/PMMA are also investigated.

  7. Genetic difference in HLA-DR phenotypes between coeliac disease and transitory gluten intolerance.

    OpenAIRE

    Meuli, R; Pichler, W J; Gaze, H; Lentze, M J

    1995-01-01

    Genetic differences in HLA phenotypes were studied in coeliac disease to investigate why some patients do not react with mucosal damage after gluten challenge. Forty five children with coeliac disease and 16 with transitory gluten intolerance were typed; 76 subjects served as controls. HLA phenotypes in children with coeliac disease had significantly higher proportions of DR3/X and DR5/7 than controls (48.8% v 11.8% and 26.7% v 5.3%). Children with transitory gluten intolerance had lower DR3/...

  8. Treating children with affect dysregulation. Discussion of Dr. Wendy Olesker's analysis of Matt.

    Science.gov (United States)

    Yanof, Judith A

    2012-01-01

    This paper is a discussion of Dr. Wendy Olesker's sensitive analytic treatment of an impulsive, affectively dysregulated, preschool child. Drawing on her knowledge and understanding of developmental interference, trauma, and conflict, Dr. Olesker uses a variety of nonverbal, interpretative, developmental, and play techniques during the analysis to help this boy progress in his development. She also works with the parents collaboratively as part of the therapeutic process. Because Dr. Olesker's description of Matt might easily fit a diagnosis of Attention Deficit Hyperactivity Disorder, it is suggested that child analysts recognize the usefulness of considering child analysis when they are evaluating or treating children with this diagnosis.

  9. Dr. Zhang's Experience in Massotherapy for Treatment of Vertebral-Artery-Type Cervical Spondylopathy

    Institute of Scientific and Technical Information of China (English)

    谢利民; 张涛

    2002-01-01

    @@ Thirty cases of vertebral-artery-type cervical spondylopathy were treated by Dr. Zhang Tao's technique. The cure rate was 50%, and the total effective rate was 100%.The vertebral-artery-type cervical spondylopathy is a commonly-seen condition in the aged people, often accompanied with arteriosclerosis. Based on the techniques performed by Dr. Du Ziming (the late famous TCM physician of our hospital), Dr. Zhang Tao has developed a set of therapeutic techniques for this condition. From June 1997 to April 1998, the author had treated 30 cases of the disease, with satisfactory results reported in the following.

  10. Dedicated to Prof. Dr.-Ing. Dr.techn. E.h. Jurjen Zierep on the occasion of his 80th birthday Transonic flows in narrow channels

    Institute of Scientific and Technical Information of China (English)

    A. Kluwick

    2009-01-01

    This article is the written version of a lecture given at the Festkolloquium on the occasion of Prof. Dr.-Ing.Dr.techn. E.h. Jurgen Zierep's 80th birthday held at the Universitat Karlsrube, 21 January 2009. It deals with laminar viscous inviscid interactions in transonic narrow channel flows. Special emphasis is placed on the internal structure of pseudo-shocks and properties of nozzle flows. Also, it is shown that the theory, first formulated for perfect gases, can easily be extended to the case of general single phase fluids.

  11. VizieR Online Data Catalog: KiDS-ESO-DR3 multi-band source catalog (de Jong+, 2017)

    NARCIS (Netherlands)

    de Jong, J. T. A.; Verdoes Kleijn, G. A.; Erben, T.; Hildebrandt, H.; Kuijken, K.; Sikkema, G.; Brescia, M.; Bilicki, M.; Napolitano, N. R.; Amaro, V.; Begeman, K. G.; Boxhoorn, D. R.; Buddelmeijer, H.; Cavuoti, S.; Getman, F.; Grado, A.; Helmich, E.; Huang, Z.; Irisarri, N.; La Barbera, F.; Longo, G.; McFarland, J. P.; Nakajima, R.; Paolillo, M.; Puddu, E.; Radovich, M.; Rifatto, A.; Tortora, C; Valentijn, E. A.; Vellucci, C.; Vriend, W-J.; Amon, A.; Blake, C.; Choi, A.; Fenech Conti, I.; Herbonnet, R.; Heymans, C.; Hoekstra, H.; Klaes, D.; Merten, J.; Miller, L.; Schneider, P.; Viola, M.

    2017-01-01

    KiDS-ESO-DR3 contains a multi-band source catalogue encompassing all publicly released tiles, a total of 440 survey tiles including the coadded images, weight maps, masks and source lists of 292 survey tiles of KiDS-ESO-DR3, adding to the 148 tiles released previously (50 in KiDS-ESO-DR1 and 98 in

  12. His Excellency Professor Dr Che-Ho Wei, Chairman, National Science Council Executive Yuan, Republic of China

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    Photo 01: Professor Dr. Che-Ho Wei signing the Guest Book with CERN Director-General, L. Maiani. Photo 02: Professor Dr. Che-Ho Wei. Photo 03::Professor Dr. Che-Ho Wei shaking hands with CERN Director-General, L. Maiani.

  13. Science Matters Podcast: Questions and Answers with EPA's Dr. Peter Grevatt

    Science.gov (United States)

    Listen to a podcast with Dr. Peter Grevatt, the director of EPA's Office of Children's Health Protection, as he answers questions about children's health, or read some of the highlights from the conversation here.

  14. New NIH Director Dr. Francis Collins on Medical Research That Benefits Everyone's Health

    Science.gov (United States)

    ... It's a marathon. Our goal is to advance biomedical research in new, innovative ways that will benefit everyone's health." — NIH Director Dr. Francis Collins Healthcare Reform— We can put science to work to better understand how to rein ...

  15. NIST Computer Scientist and Researcher Dr. Ron Ross Discusses Cybersecurity During Latest SGL

    OpenAIRE

    2010-01-01

    National Institute of Standards and Technology (NIST) senior computer scientist and information security researcher Dr. Ron Ross presented a lecture to students, staff and faculty on the new challenges in cybersecurity.

  16. 949-IJBCS-Article-Dr Ngbolua Koto-Te N J P

    African Journals Online (AJOL)

    DR GATSING

    In particular, hydro-alcoholic extracts of two Vernonia species growing in two different geographical regions(Congo DR and Madagascar) were evaluated for the inhibitory effects on two malaria ..... authentication, and adulteration detection.

  17. Eye Expert Dr. Emily Chew: 3 Ways to Keep Your Sight

    Science.gov (United States)

    ... Navigation Bar Home Current Issue Past Issues Feature: Vision Eye Expert Dr. Emily Chew: 3 Ways to ... children in the United States. Most injuries are sports-related. Outfit your child with goggles or helmet ...

  18. Transcript of speech by Dr. Ira Gabrielson to the Constitutional Convention, December 14, 1955

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Transcript of speech by Dr. Ira Gabrielson, president of Wildlife Management Institute, to Alaska Constitutional Convention, December 14, 1955.

  19. Profiles in Performing Arts Medicine Courage--A Tribute to Dr. Alice Brandfonbrener.

    Science.gov (United States)

    Manchester, Ralph A

    2015-09-01

    I was honored and privileged to join Dr. Robert Sataloff in delivering a tribute to Dr. Alice Brandfonbrener at the 2015 Symposium on the Medical Problems of Performing Artists in Snowmass, Colorado. As virtually everyone who reads this journal knows, Dr. Brandfonbrener organized the first symposium (then focused on the medical problems of musicians), was the founding editor of Medical Problems of Performing Artists, and was the first president of the Performing Arts Medicine Association. She died in 2014, just prior to last year's symposium. This year, after Dr. Sataloff presented a very engaging overview of Alice's career and impressive accomplishments, I gave a short address that was based on some of the editorials Alice wrote in this journal during her 20 year tenure as editor. I have chosen a few examples of how the courage that she demonstrated in launching an international medical conference, a peer-reviewed medical journal, and a professional association continued to present itself in her writing.

  20. Week-long celebration of Dr. Martin Luther King Jr. legacy continues

    OpenAIRE

    Owczarski, Mark

    2006-01-01

    A wide range of educational and cultural programs and community service events are underway as Virginia Tech celebrates Dr. Martin Luther King Jr. Week Jan. 15-20. All events are free (unless otherwise noted) and open to the public.

  1. Dr. Louis Sullivan: Treating America's Most Critical Health and Human Services Ills.

    Science.gov (United States)

    Cox, William E,; Matthews, Frank L.

    1989-01-01

    Interview with Dr. Louis Sullivan, Secretary of Health and Human Services. Discusses his views on health education, budget, access to health care, minority health, abortion, infant mortality, drugs, the Head Start Program, federal planning effects, and family influences. (JS)

  2. Dr. Li Chuanjie's Experience in the Acupuncture and Herbal Treatment for Coronary Heart Disease

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ Having been engaged in TCM clinical practice, teaching, and scientific research for 55 years, Dr. Li Chuanjie has obtained rich experience in treating coronary heart disease with acupuncture and herbs and got remarkable therapeutic effects.

  3. An overview of the safety pharmacology career of Dr. C.R. Hassler.

    Science.gov (United States)

    Hawk, M A; Pugsley, M K; Vinci, T; Wallery, J; Hassler, C R; Hamlin, R L

    2017-09-01

    Each year the Safety Pharmacology Society (SPS) recognizes an investigator who has had a marked impact upon the discipline. The 2016 recipient of the SPS Distinguished Service Award (DSA) was Dr. Craig R. Hassler. Dr. Hassler is one of the founding members of the SPS and has been actively engaged in physiological research for over 46years. Dr. Hassler delivered a talk entitled "My 43Years at Battelle Memorial Institute" to meeting attendees. In this article an overview is provided of the illustrious career of Dr. Hassler along with an account of the numerous animal models that were developed at Battelle under his guidance over the years. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Medieindustri og blå blok i parløb mod DR

    DEFF Research Database (Denmark)

    Hjarvard, Stig

    2016-01-01

    Et parløb mellem private medieinteresser og blå blok kan svække public service i almindelighed og DR i særdeleshed, potentielt den største svækkelse af DR siden monopolbruddet i 1988. Men hvorfor vil man svække en offentlig mediesucces i en situation, hvor det private mediemarked er voksende?...

  5. Dr Fabiola Gianotti has been selected by CERN Council to become next CERN Director General

    CERN Multimedia

    Brice, Maximilien

    2014-01-01

    With the next Director-General announced, watch the press conference starting in a few minutes via http://cern.ch/webcast/ and send your questions via Twitter to @CERNpressoffice CERN Council selects Italian physicist, Dr Fabiola Gianotti, as CERN’s next Director-General. Dr Gianotti’s mandate will begin on 1 January 2016 and run for a period of five years, read more: http://cern.ch/go/tN09F

  6. Early artificial ventilation: the mystery of "Truehead of Galveston"--was he Dr Charles William Trueheart?

    Science.gov (United States)

    Trubuhovich, Ronald V

    2008-12-01

    It seems strange that the medical literature from the United States has only a single original source of reference for a device (from circa 1870) for artificial ventilation in neonatal resuscitation. The invention is attributed to "Dr Truehead of Galveston, Texas". I argue that this mystery arises from two separate misspellings of the inventor's name, and propose that the correct name is Dr Charles William Trueheart (1837-1914), also of Galveston.

  7. Differential expression of HLA-DR antigens in subsets of human CFU-GM.

    Science.gov (United States)

    Griffin, J D; Sabbath, K D; Herrmann, F; Larcom, P; Nichols, K; Kornacki, M; Levine, H; Cannistra, S A

    1985-10-01

    Expression of HLA-DR surface antigens by granulocyte/monocyte colony-forming cells (CFU-GM) may be important in the regulation of proliferation of these cells. Using immunological techniques to enrich for progenitor cells, we investigated the expression of HLA-DR in subsets of CFU-GM. "Early" (day 14) CFU-GM express higher levels of HLA-DR than do "late" (day 7) CFU-GM. Among late CFU-GM, cells destined to form monocyte (alpha-naphthyl acetate esterase-positive) colonies express higher levels of HLA-DR than do CFU-GM destined to form granulocyte (chloroacetate esterase-positive) colonies. Because high-level expression of DR antigen was a marker for monocyte differentiation, we examined several lymphokines for their effects on both DR expression and in vitro commitment to monocyte differentiation by myeloid precursor cells. DR antigen density could be increased by more than twofold over 48 hours upon exposure to gamma-interferon (gamma-IFN), whereas colony-stimulating factors had no effect. This was associated with a dose-dependent inhibition of total CFU-GM number, and a relative, but not absolute, increase in the ratio of monocyte colonies to granulocyte colonies. Similarly, in day 7 suspension cultures of purified myeloid precursor cells, gamma-IFN inhibited cell proliferation and increased the ratio of monocytes to granulocytes. Thus, despite the induction of high levels of HLA-DR antigen on precursor cells (a marker of monocyte commitment), the dominant in vitro effect of gamma-IFN was inhibition of granulocyte differentiation.

  8. Interview with Dr. Seokhee CHO About Gifted Education and Its Future

    Directory of Open Access Journals (Sweden)

    Hüseyin MERTOL

    2014-06-01

    Full Text Available The purpose of this study, which is a major name in the education of gifted Dr. Cho 's about gifted education is to put forward their views. Dr. Seokhee Cho is a Professor at the School of Education, St. John’s University. She is currently conducting three research projects funded by US Department of Education: Project HOPE as a Principal Investigator, Project WIN and Project LEADER as a research director.

  9. Laryngology in Art: The Portrait of Dr Wilhelm Mayer-Hermann.

    Science.gov (United States)

    Patel, Amit A

    2016-12-01

    Otto Dix's portrait of the laryngologist Dr Wilhelm Mayer-Hermann represents a shining example of Neue Sachlichkeit, or New Objectivity, offering a return to unsentimental reality and a focus on the objective world, as opposed to the more abstract and idealistic tendencies of expressionism. However, precious little is known about the subject of the portrait. This article examines the portrait and attempts to shed light on the life and career of the Dr Wilhelm Mayer-Hermann.

  10. Verification of the code DYN3D/R with the help of international benchmarks

    Energy Technology Data Exchange (ETDEWEB)

    Grundmann, U.; Rohde, U.

    1997-10-01

    Different benchmarks for reactors with quadratic fuel assemblies were calculated with the code DYN3D/R. In this report comparisons with the results of the reference solutions are carried out. The results of DYN3D/R and the reference calculation for the eigenvalue k{sub eff} and the power distribution are shown for the steady-state 3-dimensional IAEA-Benchmark. The results of NEACRP-Benchmarks on control rod ejections in a standard PWR were compared with the reference solutions published by the NEA Data Bank. For assessing the accuracy of DYN3D/R results in comparison to other codes the deviations to the reference solutions are considered. Detailed comparisons with the published reference solutions of the NEA-NSC Benchmarks on uncontrolled withdrawal of control rods are made. The influence of the axial nodalization is also investigated. All in all, a good agreement of the DYN3D/R results with the reference solutions can be seen for the considered benchmark problems. (orig.) [Deutsch] Verschiedene Benchmarks fuer Reaktoren mit quadratischen Brennelementen wurden mit dem Code DYN3D/R berechnet. In diesem Bericht erfolgen Vergleiche mit den Ergebnissen der Referenzloesungen. Die Ergebnisse von DYN3D/R und der Referenzrechnung fuer Eigenwert k{sub eff} und Leistungsverteilung des stationaeren 3-dimensionalen IAEA-Benchmarks werden dargestellt. Die Ergebnisse der NEACRP-Benchmarks fuer die Auswuerfe von Steuerstaeben in einem typischen DWR werden mit den von der NEA Data Bank veroeffentlichten Referenzloesungen verglichen. Zur Einschaetzung der Genauigkeit der DYN3D/R Resultate im Vergleich zu anderen Rechenprogrammen werden die Abweichungen zu den Referenzloesungen betrachtet. Detaillierte Vergleiche mit den Referenzloesungen erfolgen fuer die NEA-NSC Benchmarks zum unkontrollierten Ausfahren von Steuerstaeben. Dabei wird der Einfluss der axialen Nodalisierung untersucht. Insgesamt wird eine gute Uebereinstimmung der DYN3D/R Resultate mit den Referenzloesungen fuer die

  11. Association of leprosy with HLA-DR2 in a Southern Brazilian population

    Directory of Open Access Journals (Sweden)

    Visentainer J.E.L.

    1997-01-01

    Full Text Available The association between HLA specificities and leprosy was investigated in a Southern Brazilian population. One hundred and twenty-one patients and 147 controls were typed for HLA-A, B, Cw, DR and DQ. Patients were subdivided into the following subgroups, according to clinical, histological and immunological criteria: lepromatous (N = 55, tuberculoid (N = 32, dimorphous (N = 20, and indeterminate (N = 14. The frequencies of HLA specificities were compared between the total group of patients and controls, and between the same controls and each subgroup of patients. After correction of the probabilities, deviations were not significant, except for the DR2 specificity, which presented a frequency of 44.2% in the total group of patients and 56.3% in the subgroup of individuals with the tuberculoid form of the disease, compared to 23.3% in the controls. Stratified analysis showed that the increased DR2 frequency in the total group of patients was due to the subgroups with the tuberculoid and dimorphous forms. The relative risk of tuberculoid leprosy for DR2-positive individuals was 4.2, and the etiologic fraction of DR2 was 0.429. In conclusion, a positive association of the DR2 specificity with the tuberculoid form of leprosy, but not with the lepromatous, dimorphous, or indeterminate forms, was demonstrated in this Southern Brazilian population

  12. The structure of HLA-DR52c: Comparison to other HLA-DRB3 alleles

    Energy Technology Data Exchange (ETDEWEB)

    Dai, Shaodong; Crawford, Frances; Marrack, Philippa; Kappler, John W. (HHMI)

    2008-09-05

    Class II major histocompatibility complex (MHCII) molecules present antigens to CD4{sup +} T cells. In addition to the most commonly studied human MHCII isotype, HLA-DR, whose {beta} chain is encoded by the HLA-DRB1 locus, several other isotypes that use the same {alpha} chain but have {beta} chains encoded by other genes. These other DR molecules also are expressed in antigen-presenting cells and are known to participate in peptide presentation to T cells and to be recognized as alloantigens by other T cells. Like some of the HLA-DRB1 alleles, several of these alternate DR molecules have been associated with specific autoimmune diseases and T cell hypersensitivity. Here we present the structure of an HLA-DR molecule (DR52c) containing one of these alternate {beta} chains (HLA-DRB3*0301) bound to a self-peptide derived from the Tu elongation factor. The molecule shares structurally conserved elements with other MHC class II molecules but has some unique features in the peptide-binding groove. Comparison of the three major HLA-DBR3 alleles (DR52a, b, and c) suggests that they were derived from one another by recombination events that scrambled the four major peptide-binding pockets at peptide positions 1, 4, 6, and 9 but left virtually no polymorphisms elsewhere in the molecules.

  13. DR3 regulation of apoptosis of naive T-lymphocytes in children with acute infectious mononucleosis.

    Science.gov (United States)

    Filatova, Elena Nikolaevna; Anisenkova, Elena Viktorovna; Presnyakova, Nataliya Borisovna; Utkin, Oleg Vladimirovich

    2016-09-01

    Acute infectious mononucleosis (AIM) is a widespread viral disease that mostly affects children. Development of AIM is accompanied by a change in the ratio of immune cells. This is provided by means of different biological processes including the regulation of apoptosis of naive T-cells. One of the potential regulators of apoptosis of T-lymphocytes is a death receptor 3 (DR3). We have studied the role of DR3 in the regulation of apoptosis of naive CD4(+) (nTh) and CD8(+) (nCTL) T-cells in healthy children and children with AIM. In healthy children as well as in children with AIM, the activation of DR3 is accompanied by inhibition of apoptosis of nTh. In healthy children, the stimulation of DR3 resulted in the increase in apoptosis of nCTL. On the contrary, in children with AIM, the level of apoptosis of nCTL decreased after DR3 activation, which is a positive contribution to the antiviral immune response. In children with AIM, nCTL are characterized by reduced level of apoptosis as compared with healthy children. These results indicate that DR3 can be involved in the reduction of sensitivity of nCTL to apoptosis in children with AIM.

  14. [Dr. Torafumi Okuyama, naval medical officer and the author of the dictionaries of medical terms].

    Science.gov (United States)

    Fukase, Y

    1996-03-01

    Dr. Genryo Torafumi Okuyama, the second son of Dr. Genchu Okuyama of the Kaminoyama clan, was born on Dec. 4th, 1847. His elder brother Dr. Toraakira Okuyama was promoted to Dai Ikan (Senior Captain), the highest rank of medical officer in the Japanese Navy, and rendered distinguished services in the establishment of the naval medical systematization in the early Meiji era. Dr. Trafumi Okuyama, who was appointed as medical officer of the Yokohama army Hospital and transferred to Daibyoin in Edo, was engaged in medical treatment of injured soldiers during the Boshin-war in 1868. He went to Kagoshima with William Willis and as one of the founders of the Kagoshima Medical school, gave students education there. He resigned his naval position in 1874, when he was Dai Gun I (Senior Leutenant) and died at the age of 41 in April 16th 1887. Dr. Torafumi Okuyama compiled A medical vocabulary in English and Japanese ("Igo Ruizyu") and Deutsch-Japanisches Hand-Wörterbuch für Medizin ("Dokuwa Igaku Ziten) and published "Koen Hikki", the translation of the lectures by Dr. Edwin Wheeler.

  15. Visit of H.E. Dr Abdolrahim Gavahi, Secretary General, Economic Cooperation Organization, Islamic Republic of Iran

    CERN Multimedia

    Patrice Loïez

    2001-01-01

    Photo 01: L.to r. Prof. Galileo Violini, Head, UNESCO Office, Teheran; Mr Jan van der Boon, CERN Director of Administration; H.E. Dr Abdolrahim Gavahi, Secretary General, Economic Cooperation Organization, Islamic Republic of Iran (signing the Guest Book); Dr John Ellis, CERN Adviser for Non-Member State Relations and Dr Behzad Alipour Tehrany Photo 02: Mr Jan van der Boon, CERN Director of Administration (left) and Dr John Ellis, CERN Adviser for Non-Member State Relations (right) on the occasion of the visit of H.E. Dr Abdolrahim Gavahi, Secretary General, Economic Cooperation Organization, Islamic Republic of Iran.

  16. Devices for DR (differential-residual) protection for plug circuits in IT systems; Dispositivos de protecao DR para circuitos de tomadas em sistemas IT

    Energy Technology Data Exchange (ETDEWEB)

    Hoermann, W.

    2010-02-15

    The German regulation DIN VDE 0100-410 and the ABNT NBR 5410 are based on the international IEC 60364. In its more recent publication (2007), prescribes one or more protection differential-residual (DR) of high sensitiveness for plugs up to 20 A in new electrical installations. The paper approaches the implementation of the requisites for an industrial application at IT networks. (author)

  17. New ultracool subdwarfs identified in large-scale surveys using Virtual Observatory tools: Part I: UKIDSS LAS DR5 vs SDSS DR7

    CERN Document Server

    Lodieu, N; Osorio, M R Zapatero; Solano, E; Aberasturi, M; Martín, E L

    2012-01-01

    The aim of the project is to improve our knowledge on the low-mass and low-metallicity population to investigate the influence of metallicity of the stellar (and substellar) mass function. We present the results of a photometric and proper motion search aimed at unearthing ultracool subdwarfs in large-scale surveys. We employed and combined the UKIDSS LAS DR5 and the SDSS DR7 complemented with ancillary data from 2MASS, DENIS and SuperCOSMOS. The SDSS DR7 vs UKIDSS LAS DR5 search returned a total of 32 ultracool subdwarf candidates, only two being recognised as a subdwarf in the literature. Twenty-seven candidates were followed-up spectroscopically in the optical between 600 and 1000 nm. We confirmed 20 candidates as subdwarfs, extreme subdwarfs or ultra-subdwarfs with spectral types later than M5; this represents a success rate of ~60%. Among those 20 new subdwarfs, we identified 2 early-L subdwarfs very likely located within 100 pc that we propose as templates for future searches because they are the first ...

  18. Sevgili Dr Zeki Soysal’i Duşunurken

    Directory of Open Access Journals (Sweden)

    Kriton Dinçmen

    2006-12-01

    Full Text Available Dr. Kriton DİNÇMEN ... zaman öylesine geçiyor, ki... daha dün gibi, hepimiz Adli Tıp Kurumu’nun girişindeki meydanlıkta toplanmıştık... karşımızda O’nun tabutu... gözlerimiz dolu, gönlümüz ağır, ruhumuz yıkık o çalışkan, duru, tertemiz, nazik, içtenlikli, vefakar, bilgili... o hep insanca gülümseyen güzel insanı yeni yeni çıktığı uzun yolculuğuna uğurluyorduk. Prof. Dr. Zeki Soysal çok iyi bir hekimdi. Ne yazıktır, şimdilerde ortaya çıktığına tanık olduğumuz eğitimini hiç görmediği konularda dahi, yüzeysel bilgilerle, ağır sorumlulukları gerektiren pozisyonları alacak kadar ‘cesur’ olanların zıddına, gerçek bir bilim adamı, gerçek bir akademisyendi. Adli Tıp akademisyeni olmasının yanında, ikinci bir ihtisas olarak Kadın-Doğum ihtisasını bitirdiğinde, jinekolog hocalarının kendisi hakkında yapmış oldukları methiyeler hepimizin kulağındadır... Ve, doğaldır ki, hepimizin hekim vicdanı bizlerin genç meslektaşımıza duymakta olduğu sevgi ile amalgamlaşmış saygıyı da arttırmıştır. Hatırlıyorum... Adli Tıp Kurumu’nda IV. İhtisas Kurulu’nun sorumluluğunu taşıdığım yıllarda, genelde, geç çıkıyordum. Odamın penceresi çok defa akşam 9.00, 9.30 hatta 10.00’a kadar yanardı... Kurumda o saatlere kadar penceresi yanan ikinci bir oda sevgili Zekiciğimin odası idi. Ya o, ya da ben birbirimizin ‘geç çıkma’ rekorunu kırardık... Benim işim onunkinden biraz fazla sürdüğünde Zeki kapımı çalar, başını uzatır ve ‘ağabey, bu gün rekor sende... bana eyvallah ...’ diye takılırdı... gülümserdi... o insan gülümsemesi ile... o içtenlikli, alçak gönüllü... o ‘kendinden emin’ bir bilim adamının bir hekimin gülümsemesi ile... İkimiz arasında pek çok kimsenin fark etmemiş olduğu bir gerçek ağabey-kardeş ... daha doğrusu bir amca-yeğen ilişkisi vardı... Ve şimdi d

  19. DR AVRAM JOZEF VINAVER (1862-1915) - PIONEER OF RADIOLOGY IN SERBIA.

    Science.gov (United States)

    Babić, Rade Radomir; Stanković Babić, Gordana

    2015-01-01

    Dr Abraham Joseph Vinaver (1862-1915), a Jew from Poland, was a pioneer of radiology in Serbia. He graduated from the Faculty of Medicine in Warsaw (1887), but lived and worked in abac (the Kingdom of Serbia) since 1890. Dr Abraham Joseph Vinarev - Career Development. He procured the first X-ray machine and developed radiological service in Sabac five years after the discovery of X-rays. These were the beginnings of radiology in Serbia. He introduced the application of artesian wells. Dr Abraham Joseph Vinarev - a Participant at the First Congress of Serbian Physicians and Naturalists, Belgrade 1904. "The diagnostic importance of X-rays in lung disease, especially in initial tuberculosis" and "Five Years of Treatment by X-Ray Machines" were the first works in the field of radiology in Serbia by this author. Dr Abraham Joseph Vinaver - Reserve Medical Officer in the Serbian Army. During the Balkan Wars, he was a volunteer with the rank of major engaged in military corps and he participated in the First World War as well. He died of malaria in 1915 in Gevgelija. "Dr Avram Vinaver"- Stanislav Vinarev. His dedication to work during the typhus epidemics was put into verses of a poem by his son Stanislav Vinarev. Dr Avram Vinaver Joseph was a noble man with a great heart, who selflessly sacrificed himself for the Serbian people and Serbia. He gave his contribution to the development of health services in Serbia, both in peacetime and wartime conditions. Dr Abraham Joseph Vinaver laid the foundations for today's radiology in Serbia.

  20. Dr Avram Jozef Vinaver (1862-1915: Pioneer of radiology in Serbia

    Directory of Open Access Journals (Sweden)

    Babić Rade Radomir

    2015-01-01

    Full Text Available Introduction. Dr Abraham Joseph Vinaver (1862-1915, a Jew from Poland, was a pioneer of radiology in Serbia. He graduated from the Faculty of Medicine in Warsaw (1887, but lived and worked in Šabac (the Kingdom of Serbia since 1890. Dr Abraham Joseph Vinarev - Career Development. He procured the first X-ray machine and developed radiological service in Šabac five years after the discovery of X-rays. These were the beginnings of radiology in Serbia. He introduced the application of artesian wells. Dr Abraham Joseph Vinarev - a Participant at the First Congress of Serbian Physicians and Naturalists, Belgrade 1904. “The diagnostic importance of X-rays in lung disease, especially in initial tuberculosis” and “Five Years of Treatment by X-Ray Machines” were the first works in the field of radiology in Serbia by this author. Dr Abraham Joseph Vinaver - Reserve Medical Officer in the Serbian Army. During the Balkan Wars, he was a volunteer with the rank of major engaged in military corps and he participated in the First World War as well. He died of malaria in 1915 in Gevgelija. “Dr Avram Vinaver”- Stanislav Vinarev. His dedication to work during the typhus epidemics was put into verses of a poem by his son Stanislav Vinarev. Conclusion. Dr Avram Vinaver Joseph was a noble man with a great heart, who selflessly sacrificed himself for the Serbian people and Serbia. He gave his contribution to the development of health services in Serbia, both in peacetime and wartime conditions. Dr Abraham Joseph Vinaver laid the foundations for today’s radiology in Serbia.

  1. Assessment of DR-55 as a Drop-In Replacement for R-410A

    Energy Technology Data Exchange (ETDEWEB)

    Shen, Bo [ORNL; Abdelaziz, Omar [ORNL

    2016-01-01

    R410A has no ozone depletion potential (ODP), and is the most commonly used refrigerant in vapor compression systems for space cooling and heating applications. However, it has significant global warming potential with GWP higher than 1900. To mitigate the global warming effect, industry and research institutes are actively pursuing a replacement for R-410A with the following attributes, much lower GWP along with similar or higher efficiency and capacity. DR-55 (aka R452B) is a design-compatible refrigerant replacement for R-410A. It decreases the GWP by 70%, and has lower working pressure, comparable discharge temperature, and uses the same lubricant, tubing, and valves. In this study, we experimentally evaluated the performance of DR-55 as a drop-in replacement for R-410A in a high efficiency rooftop air conditioning unit. The experimental results demonstrated that DR-55 led to 5% higher efficiency at the working conditions of Integrated Energy Efficiency Rating (IEER). DR-55 also showed significantly better high ambient performance from 95 F to 125 F. In addition to the experimental study, we used the DOE/ORNL Heat Pump Design Model to model the RTU using R-410A and DR-55, respectively. The model results were compared to the laboratory measurements. The model validation demonstrates that the refrigerant heat transfer and pressure drop correlations, developed for conventional refrigerants like R-410A, are usable for DR-55. Also, a converted compressor model for DR-55, i.e. reducing volumetric and isentropic efficiencies as a function of the suction and discharge pressures from an R-410A compressor map can predict the compressor mass flow rate and power accurately.

  2. Structural Insight for Roles of DR5 Death Domain Mutations on Oligomerization of DR5 Death Domain-FADD Complex in the Death-Inducing Signaling Complex Formation: A Computational Study.

    Science.gov (United States)

    Yang, Hongyi; Song, Yuhua

    2016-04-01

    Death receptor 5 (DR5)-induced apoptosis that prioritizes the death of tumor cells has been proposed as one of the promising cancer therapies. In this process, oligomerized DR5 death domain (DD) binding to Fas-associated death domain (FADD) leads to FADD activating caspase-8, which marks the formation of the death-inducing signaling complex (DISC) that initiates apoptosis. DR5 DD mutations found in cancer cells have been suggested to play an important pathological role, the mechanism through which those mutants prevent the DR5-activated DISC formation is not clear yet. This study sought to provide structural and molecular insight for the roles of four selected DR5 DD mutations (E355K, E367K, K415N, and L363F) in the oligomerization of DR5 DD-FADD complex during the DISC formation. Results from the molecular dynamics simulations show that the simulated mutants induce conformational, dynamical motions and interactions changes in the DR5 DD-FADD tetramer complex, including changes in a protein's backbone flexibility, less exposure of FADD DED's caspase-8 binding site, reduced H-bonding and hydrophobic contacts at the DR5 DD-FADD DD binding, altered distribution of the electrostatic potentials and correlated motions of residues, and reduced binding affinity of DR5 DD binding to FADD. This study provides structural and molecular insight for the influence of DR5 DD mutations on oligomerization of DR5 DD-FADD complex, which is expected to foster understanding of the DR5 DD mutants' resistance mechanism against DR5-activated DISC formation.

  3. Dr. PIAS: an integrative system for assessing the druggability of protein-protein interactions

    Directory of Open Access Journals (Sweden)

    Furuya Toshio

    2011-02-01

    Full Text Available Abstract Background The amount of data on protein-protein interactions (PPIs available in public databases and in the literature has rapidly expanded in recent years. PPI data can provide useful information for researchers in pharmacology and medicine as well as those in interactome studies. There is urgent need for a novel methodology or software allowing the efficient utilization of PPI data in pharmacology and medicine. Results To address this need, we have developed the 'Druggable Protein-protein Interaction Assessment System' (Dr. PIAS. Dr. PIAS has a meta-database that stores various types of information (tertiary structures, drugs/chemicals, and biological functions associated with PPIs retrieved from public sources. By integrating this information, Dr. PIAS assesses whether a PPI is druggable as a target for small chemical ligands by using a supervised machine-learning method, support vector machine (SVM. Dr. PIAS holds not only known druggable PPIs but also all PPIs of human, mouse, rat, and human immunodeficiency virus (HIV proteins identified to date. Conclusions The design concept of Dr. PIAS is distinct from other published PPI databases in that it focuses on selecting the PPIs most likely to make good drug targets, rather than merely collecting PPI data.

  4. A portrait of the extreme Solar System object 2012 DR30

    CERN Document Server

    Kiss, Cs; Horner, J; Conn, B C; Müller, T G; Vilenius, E; Sárneczky, K; Kiss, L L; Bannister, M; Bayliss, D; Pál, A; Góbi, S; Verebélyi, E; ~Lellouch, E; Santos-Sanz, P; Ortiz, J L; Duffard, R; Morales, N

    2013-01-01

    2012 DR30 is a recently discovered Solar System object on a unique orbit, with a high eccentricity of 0.9867, a perihelion distance of 14.54 AU and a semi-major axis of 1109 AU, in this respect outscoring the vast majority of trans-Neptunian objects. We performed Herschel/PACS and optical photometry to uncover the size and albedo of 2012 DR30, together with its thermal and surface properties. The body is 185 km in diameter and has a relatively low V-band geometric albedo of ~8%. Although the colours of the object indicate that 2012 DR30 is an RI taxonomy class TNO or Centaur, we detected an absorption feature in the Z-band that is uncommon among these bodies. A dynamical analysis of the target's orbit shows that 2012 DR30 moves on a relatively unstable orbit and was most likely only recently placed on its current orbit from the most distant and still highly unexplored regions of the Solar System. If categorised on dynamical grounds 2012 DR30 is the largest Damocloid and/or high inclination Centaur observed so...

  5. 老贾谈EFFIE Dr Pepper:全新的主流理念

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    众所周知,长期以来可口可乐和百事可乐一直占据着整个美国软饮料市场。“可乐”这一核心名词一度成为软饮料市场的代名词。为了能够成功的进入本土软饮料市场,并且将自身品牌提升到一个全新的高度与广度,Dr Pepper决定以“非可乐”型饮料作为产品的定位,带动旗下的Dr Pep—per与Diet Dr Pepper一起启动品牌拓展计划。

  6. Collected Papers in Structural Mechanics Honoring Dr. James H. Starnes, Jr.

    Science.gov (United States)

    Knight, Norman F., Jr. (Compiler); Nemeth, Michael P. (Compiler); Malone, John B. (Compiler)

    2006-01-01

    This special publication contains a collection of structural mechanics papers honoring Dr. James H. Starnes, Jr. presented at the 46th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference held in Austin, Texas, April 18-21, 2005. Contributors to this publication represent a small number of those influenced by Dr. Starnes' technical leadership, his technical prowess and diversity, and his technical breath and depth in engineering mechanics. These papers cover some of the research areas Dr. Starnes investigated, which included buckling, postbuckling, and collapse of structures; composite structural mechanics, residual strength and damage tolerance of metallic and composite structures; and aircraft structural design, certification and verification. He actively pursued technical understanding and clarity, championed technical excellence, and modeled humility and perseverance.

  7. VizieR Online Data Catalog: PACS Evolutionary Probe (PEP-DR1) catalogs (Lutz+, 2011)

    Science.gov (United States)

    Lutz, D.; Poglitsch, A.; Altieri, B.; Andreani, P.; Aussel, H.; Berta, S.; Bongiovanni, A.; Brisbin, D.; Cava, A.; Cepa, J.; Cimatti, A.; Daddi, E.; Dominguez-Sanchez, H.; Elbaz, D.; Foerster Schreiber, N. M.; Genzel, R.; Grazian, A.; Gruppioni, C.; Harwit, M.; Le Floc'h, E.; Magdis, G.; Magnelli, B.; Maiolino, R.; Nordon, R.; Perez Garcia, A. M.; Popesso, P.; Pozzi, F.; Riguccini, L.; Rodighiero, G.; Saintonge, A.; Sanchez Portal, M.; Santini, P.; Shao, L.; Sturm, E.; Tacconi, L. J.; Valtchanov, I.; Wetzstein, M.; Wieprecht, E.

    2013-11-01

    PACS catalogs built by the PEP team, with key contributions by Stefano Berta, Benjamin Magnelli, Paola Popesso, Dieter Lutz, Francesca Pozzi, Bruno Altieri, Herve Aussel, Hoseong Hwang, Emeric Le Floc'h, Georgios Magdis, Raanan Nordon, Albrecht Poglitsch, Laurie Riguccini, Amelie Saintonge, Li Shao. For more details, please refer to Lutz et al. (2011A&A...532A..90L) and to the PDF documentation associated to the release. Data and catalogs can be retrieved from the web page http://www.mpe.mpg.de/ir/Research/PEP/publicdatareleases.php See the PDF documentation associated to the PEP DR1 release, http://www.mpe.mpg.de/resources/PEP/DR1tarballs/readmePEP_global.pdf and http://www.mpe.mpg.de/resources/PEP/DR1tarballs/readmePEP_SPIRE.pdf for more details. (69 data files).

  8. Pressure loss tests for DR-BEP of fullsize 17 x 17 PWR fuel assembly

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Moon Ki; Chun, Se Young; Chang, Seok Kyu; Won, Soon Youn; Cho, Young Rho; Kim, Bok Deuk; Min, Kyoung Ho [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1993-01-01

    This report describes the conditions, procedure and results in the pressure loss tests carried out for a double grid type debris resistance bottom end piece (DR-BEP) designed by KAERI. In this test, the pressure loss coefficients of the full size 17 x 17 PWR simulated fuel assembly with DR-BET and with standard-BEP were measured respectively, and the pressure loss coefficients of DR-BEP were compared with the coefficients of STD-BET. The test conditions fall within the ranges of loop pressure from 5.2 to 45 bar, loop temperature from 27 to 221 deg C and Reynolds number in fuel bundle from 2.17 x 10{sup 4} to 3.85 x 10{sup 5}. (Author) 5 refs., 18 figs., 5 tabs.

  9. The Case of Dr. Oz: Ethics, Evidence, and Does Professional Self-Regulation Work?

    Science.gov (United States)

    Tilburt, Jon C; Allyse, Megan; Hafferty, Frederic W

    2017-02-01

    Dr. Mehmet Oz is widely known not just as a successful media personality donning the title "America's Doctor(®)," but, we suggest, also as a physician visibly out of step with his profession. A recent, unsuccessful attempt to censure Dr. Oz raises the issue of whether the medical profession can effectively self-regulate at all. It also raises concern that the medical profession's self-regulation might be selectively activated, perhaps only when the subject of professional censure has achieved a level of public visibility. We argue here that the medical profession must look at itself with a healthy dose of self-doubt about whether it has sufficient knowledge of or handle on the less visible Dr. "Ozes" quietly operating under the profession's presumptive endorsement.

  10. [Dr. Puigvert and Archivos Españoles de Urología].

    Science.gov (United States)

    Pérez Albacete, Mariano

    2006-04-01

    For the celebration of the first Century of Dr. Antonio Puigvert Gorro's birth we want to know his contribution to and relationship with Archivos Españoles de Urología. We review all articles published by Dr. Puigvert, and additionally all articles with reference to his person and his work; we also review his written works and biography. He was one of the founders of the journal and always maintained a great cooperation until the '70s; he published important works in it, which are analyzed. We also emphasize his contribution to Urology in addition to his dedication to the history of the speciality. Dr. Puigvert is one of the most distinguished figures in the Spanish Urology, with an immense working capacity and written works. In his works published in Archivos he presents the results of his observations and his studies, as well as part of his innovations, ideas, and discoveries, that he later left in his urology books.

  11. HLA-DR4 and career prospects in rheumatology: is there a link?

    Science.gov (United States)

    Gough, A.; Faint, J.; Salmon, M.; Bacon, P.; Emery, P.

    1995-01-01

    OBJECTIVE--To determine whether HLA type is associated with career progress in rheumatology. DESIGN--Comparison of HLA type after HLA analysis of samples of venous blood. SETTING--Department of Rheumatology Research, University of Birmingham. SUBJECTS--All (37) staff in the department. RESULTS--All the senior academics and most staff with a PhD expressed HLA-DR4. The prevalence of expression in each of these groups was significantly greater than that found in the controls. None of the junior doctors or secretaries expressed DR4. CONCLUSION--The junior doctors in the department have poor career prospects as HLA-DR4 seems to be associated with academic achievement. Images p1666-a PMID:8541751

  12. Expression of TRAIL and death receptor DR4 in Palmer type 2 TFCC lesions.

    Science.gov (United States)

    Unglaub, Frank; Thomas, Susanne B; Kroeber, Markus W; Dragu, Adrian; Fellenberg, Jörg; Mittlmeier, Thomas; Wolf, Maya B; Horch, Raymund E

    2010-10-01

    Degenerative articular disc perforations of the triangular fibrocartilage (TFC) of the wrist are characterized by fibrocartilage cell loss and are often associated with ulna-plus situations. Apoptosis has been found to play a crucial role in fibrocartilage cell loss, however, the molecular mechanism and mediators are still poorly understood. The purpose of this study was to identify receptors to apoptosis in degenerative disc lesions. Included in the study were 17 patients with degenerative articular disc tears of the TFC (Palmer type 2C). Following arthroscopic debridement of the TFC, histological sections were examined to assess the presence of apoptosis. Apoptosis was determined using TRAIL and death receptor DR4 agonists for immunohistochemical analyses. The number of cells positive for apoptosis was then correlated with ulna length. Cells positive for TRAIL and DR4 were found in all specimens. The number of cells positive for TRAIL was significantly increased in specimens of patients with an ulna positive variance (P = 0.040). However, DR4 was not significantly increased in ulna plus (P > 0.05). Both, TRAIL and DR4 positive cells were found to be evenly distributed throughout each specimen. There was no accumulation of any type of cells in any particular zone of the biopsies. This is the first study that shows that TFCC cells express TRAIL and DR4, which suggests that apoptosis, as well as, mechanical trauma are involved in the development of disc perforation. The TRAIL/DR4 receptor system is a molecular mediator of apoptosis induction in TFC cells and therefore plays a role in cell loss in degenerative disc lesions.

  13. DR-induced escape of O and C from early Mars

    Science.gov (United States)

    Zhao, Jinjin; Tian, Feng; Ni, Yufang; Huang, Xiaomeng

    2017-03-01

    Energetic particles produced in Dissociative recombination (DR) reactions could escape planets with low gravity, such as Mars, if they could overcome collisions with the surrounding background gases. In this work, a 3-D Monte Carlo model is developed to study these photochemical escape processes on early Mars. Although the DR reaction rates of O2+, CO2+, and CO+ increase monotonically with solar soft X-ray and extreme ultraviolet (XUV) flux, the peak of the calculated DR-induced escape rates of O is near 3 × XUV, and the DR-induced escape rates of C increase with XUV until 10 × XUV. The non-monotonic behavior can be explained by the increased column densities of background species in high XUV conditions, which can deflect energetic particles through collisions more efficiently. At 20 × XUV, CO+ DR is the main source of escaping O and C, and the escape of secondary particles could contribute to 30∼40% and 10% of the total escape of O and C respectively. The time-integrated DR-induced escape of O and C is equivalent to 1 m of H2O and 20 mbar of CO2 escaping early Mars since 4.5 billion years ago. The accumulated CO2 loss is much lower than what's needed to explain the carbon isotopic ratios on Mars and much lower than the total CO2 needed to warm up early Mars. If more vigorous escape mechanisms were absent on early Mars, substantial inventories of volatiles have not been detected yet.

  14. Association between risk for pre-eclampsia and HLA DR4

    Energy Technology Data Exchange (ETDEWEB)

    1990-03-17

    Dr. Kilpatrick and colleagues report results of a family study showing an association between HLA DR4 and mild and proteinuric pre-eclampsia in a British (Edinburgh) maternal population. Among 76 parous sisters of women with protein uric pre-eclampsia, they found that sisters with pregnancy-induced hypertension (pre-eclampsia with or without proteinuria) had a higher frequency of HLA DR4 antigen than did normotensive sisters. In addition, they cited unpublished findings in which they found a higher frequency of HLA DR4 antigen in a large sample of pre-eclamptic women and their babies than in appropriate controls. The authors have completed a study of HLA antigens and pregnancy outcome among a coherent of 715 black (50.9%) and white (49.1%) primigravida who were delivered at a medical center in southern USA. HLA DR typing was done by the one-color fluorescence technique with reagents. On the basis of standard criteria for diagnosis of pre-eclampsia and eclampsia, 6.9 of the cohort had mild non-proteinuric pre-eclampsia, 8.8% had pregnancy-induced hypertension, and 9.5% had combined pre-eclampsia and eclampsia. Whereas black women had higher rates than white women in all three clinical categories (eg, pregnancy-induced hypertension 10.7% vs 6.8%, respectively), differences were not significant and frequencies of HLA DR4 antigen were higher among normotensives in both races (results not shown). They therefore pooled the two racial groups for analyses.

  15. Intra HLA-D/DR region recombinant detected by primed lymphocyte typing (PLT)

    DEFF Research Database (Denmark)

    Jakobsen, B K; Kristensen, T; Lamm, L U

    1983-01-01

    The chromosome 6 markers, HLA-ABC, D, DR, MT, properdin factor Bf, and complement factors 2 (C2) and 5 (C4), were studied in three families, each of which included two HLA identical siblings, one or both of whom were known to be HLA-B: GLO recombinants. The families were also typed with primed...... lymphocyte typing (PLT) for HLA-D/DR region associated DP antigens. None of these studies gave evidence that the recombinations had occurred within the HLA region. Mixed leucocyte culture (MLC) tests within the families showed no detectable stimulation between the HLA identical siblings in two...

  16. MASTER AND PUPIL – DR. JÁN BRTEK AND I

    Directory of Open Access Journals (Sweden)

    Hidetoshi NAGANAWA

    2008-06-01

    Full Text Available Large branchiopod studies were born and bred in the Danube basin in some Eastern European countries (the former Czechoslovakia, Hungary, and Romania. The leading expert was the late Dr. Ján Brtek in Slovakia. Large branchiopods are usually habitants of such temporary lakes and ponds as inland bodies of fresh, mineralized, salt water or hypersaline. This article has two distinct goals: (1 to review the history of large branchiopod studies and (2 to draw attention to some of the scientific interest and value of ephemeral aquatic habitats, introducing my reminiscences of Dr. Brtek.

  17. Immunohistochemical Study of HLA-DR Antigen in Endometrial Tissue of Patients with Endometriosis

    Institute of Scientific and Technical Information of China (English)

    刘义; 罗丽兰; 赵海波

    2002-01-01

    In order to evaluate the expression of HLA-DR antigen in glandular cells in eutopic and ectopic endometrium in patients with endometriosis, 19 infertile patients with endometriosis were analyzed immunohistochemically by labelled streptavidin biotin (LSAB) method. Nineteen infertile patients without endometriosis were studied as controls. The results showed that the expression of HLA-DR antigen in the glandular cells in both eutopic and ectopic endometrium was increased significantly as compared with that in the controls (P<0.01). It is likely that aberrant expression of HLADR antigen in endometriotic tissue is involved in abormal immunogenesis of endometriosis.

  18. Characterization of a Novel Anti-DR5 Monoclonal Antibody WD1 with the Potential to Induce Tumor Cell Apoptosis

    Institute of Scientific and Technical Information of China (English)

    Jing Wang; Beifen Shen; Yuanfang Ma; Yan Li; Zhou Lin; Chunxia Qiao; Ming Lv; Ming Yu; He Xiao; Qingyang Wang; Liyan Wang; Jiannan Feng

    2008-01-01

    TNF-related apoptosis. inducing ligand (TRAIL) is a TNF family member capable of inducing apoptosis. Death receptor 5(DR 51 is a key receptor of TRAIL and plays an important role in TRAIL-induced apoptosis. To prepare monoclonal antibodies (mAbs) against DR5, cDNA encoding soluble DR5(sDR5)was firstly amplified by revere transcriptase. polymerase chain reaction (RT-PCR) with specific primers, and then inserted into a prokaryotic expression vector pET-30a. The recombinant plasmid Was expressed in Escherichia coil strain BL21(DE3), and sDR5 was purified by nickel affinity chromatography. As an antigen. sDR5 Was used to immunize mice. Hybridomas secreting antibodies against sDR5 were identified. One positive clone Was selected to produce antibody, WD1. ELISA and immunofluorescence demonstrated that WD1 could bind recombinant sDR5 and membrane bound DR5 (mDR5)on Jurkat and Molt-4 cells. ATPLite assays showed that Jurkat and Molt-4 cells were sensitive to the antibody in a dose dependent manner. The Annexin V/PI assays and Giemsa's staining both showed that WD1 could induce Jurkat cell apoptosis efficiently. Transient transfection of 293T cells and indirect immunofluorescence assay demonstrated that mAb(WD1)couldn't cross. react with DR4.Our findings indicated that the novel antibody, WD1 could act as a direct agonist, bind DR5 characteristically, and initiate efficient apoptotic signaling and tumor regression. Thus, WD1 would be a leading candidate for potential cancer therapeutics. Cellular & Molecular Immunology. 2008;5(1):55-60.

  19. BEopt-CA (Ex): A Tool for Optimal Integration of EE, DR and PV in Existing California Homes

    Energy Technology Data Exchange (ETDEWEB)

    Christensen, Craig [National Renewable Energy Lab. (NREL), Golden, CO (United States); Horowitz, Scott [National Renewable Energy Lab. (NREL), Golden, CO (United States); Maguire, Jeff [National Renewable Energy Lab. (NREL), Golden, CO (United States); Velasco, Paulo Tabrares [National Renewable Energy Lab. (NREL), Golden, CO (United States); Springer, David [Davis Energy Group, Davis, CA (United States); Coates, Peter [Davis Energy Group, Davis, CA (United States); Bell, Christy [Davis Energy Group, Davis, CA (United States); Price, Snuller [Energy & Environmental Economics, San Francisco, CA (United States); Sreedharan, Priya [Energy & Environmental Economics, San Francisco, CA (United States); Pickrell, Katie [Energy & Environmental Economics, San Francisco, CA (United States)

    2014-04-01

    This project targeted the development of a software tool, BEopt-CA (Ex) (Building Energy Optimization Tool for California Existing Homes), that aims to facilitate balanced integration of energy efficiency (EE), demand response (DR), and photovoltaics (PV) in the residential retrofit1 market. The intent is to provide utility program managers and contractors in the EE/DR/PV marketplace with a means of balancing the integration of EE, DR, and PV

  20. HLA-DR+ Immature Cells Exhibit Reduced Antigen-Presenting Cell Function But Respond to CD40 Stimulation

    Directory of Open Access Journals (Sweden)

    Alberto Pinzon-Charry

    2005-12-01

    Full Text Available Dendritic cells (DC have been implicated in the defective function of the immune system during cancer progression. We have demonstrated that patients with cancer have fewer myeloid (CD11c+ and plasmacytoid (CD123hi DC and a concurrent accumulation of CD11c−CD123− immature cells expressing HLA-DR (DR+IC. Notably, DR+IC from cancer patients have a reduced capacity to stimulate allogeneic T-cells. DR+IC are also present in healthy donors, albeit in smaller numbers. In this study, we assessed whether DR+IC could have an impact on the immune response by comparing their function with DC counterparts. For this purpose, DR+IC and DC were purified and tested in the presentation of antigens through major histocompatibility complex (MHC II and MHC-I molecules. DR+IC were less efficient than DC at presenting antigens to T-cells. DR`IC induced a limited activation of T-cells, eliciting poor T-helper (Th 1 and preferentially inducing Th2-biased responses. Importantly, despite DR+IC's poor responsiveness to inflammatory factors, in samples from healthy volunteers and breast cancer patients, CD40 ligation induced phenotypic maturation and interleukin 12 secretion, in turn generating more efficient T-cell responses. These data underscore the importance of inefficient antigen presentation as a mechanism for tumor evasion and suggest an approach to improve the efficacy of DC-based immunotherapy for cancer.

  1. Human radiation studies: Remembering the early years. Oral history of Dr. George Voelz, M.D., November 29, 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-05-01

    Dr. George Voelz was interviewed by representatives of the US DOE Office of Human Radiation Experiments (OHRE). This oral history covers Dr. Voelz`s research on Manhattan Engineering District plutonium workers, the acute and long term effects of radiation, his inhalation studies, and his activities at the 1961 INL reactor accident (SL-1 Reactor). After a brief biographical sketch, Dr. Voelz his remembrances on tissue studies of plutonium workers, the plutonium injection studies of 1945-1946, the controlled environmental radioiodine tests of 1963-1968, and tracer studies with human volunteers at Los Alamos. Dr. Voelz states his opinions concerning misconceptions about the Los Alamos Human Radiation Experiments.

  2. MTB-DR-RIF 9G test: Detection and discrimination of tuberculosis and multi-drug resistant tuberculosis strains.

    Science.gov (United States)

    Song, Keum-Soo; Nimse, Satish Balasaheb; Cho, Nam Hoon; Sung, Nackmoon; Kim, Hee-Jin; Yang, Jeongseong; Kim, Taisun

    2015-12-01

    This report describes the evaluation of the novel MTB-DR-RIF 9G test for the accurate detection and discrimination of Mycobacterium tuberculosis (MTB) and rifampicin-resistant M. tuberculosis (MTB-DR-RIF) in the clinical samples. The procedure included the amplification of a nucleotide fragment of the rpoB gene of the MTB and MTB-DR-RIF strains and their hybridization with the immobilized probes. The MTB-DR-RIF 9G test was evaluated for its ability to detect and discriminate MTB and MTB-DR-RIF strains in 113 known clinical samples. The accuracy of the MTB-DR-RIF 9G test was determined by comparing its results with sequencing analysis and drug susceptibility testing. The sensitivity and specificity of the MTB-DR-RIF 9G test at 95% confidence interval were found to be 95.4% (89.5-98.5) and 100% (69.2-100), respectively. The positive predictive value and negative predictive value of the MTB-DR-RIF 9G test at 95% confidence interval were found to be 100% (85.0-95.9) and 66.7% (38.4-88.18), respectively. Sequencing analysis of all samples indicated that the mutations present in the regions identified with the MTB-DR-RIF 9G assay can be detected accurately.

  3. Dr. Strangelove: Or How I Learned To Stop Worrying and Teach the Film in the Classroom.

    Science.gov (United States)

    Lowery, J. Vincent

    2002-01-01

    Presents a lesson plan focusing on the film, "Dr. Strangelove" by Stanley Kubrick, and describes the film in detail. Reviews the historical background about the film to assist students in understanding the themes presented. Discusses the characters in the film and their possible real-life counterparts. (CMK)

  4. UltraVISTA Catalogue Release DR1 (McCracken+, 2012)

    NARCIS (Netherlands)

    McCracken, H. J.; Milvang-Jensen, B.; Dunlop, J.; Franx, M.; Fynbo, J. P. U.; Le Fevre, O.; Holt, J.; Caputi, K. I.; Goranova, Y.; Buitrago, F.; Emerson, J. P.; Freudling, P. Hudelot W.; Lopez-Sanjuan, C.; Magnard, F.; Mellier, Y.; Moller, P.; Nilsson, K. K.; Sutherland, W.; Tasca, L.; Zabl, J.

    2012-01-01

    Matched source catalogue prepared for the first UltraVISTA (DR1 catalogue release. To 5σ limit, our Ks -selected catalogue contains 216268 sources observed in Y, J, H and Ks bands over the full UltraVISTA deep area (~1.3deg2), with NB118 observation over the "ultra-deep stripes" area. (2 data files)

  5. Strong CH+ J = 1-0 emission and absorption in DR21

    NARCIS (Netherlands)

    Falgarone, E.; Ossenkopf, V.; Gerin, M.; Lesaffre, P.; Godard, B.; Pearson, J.; Cabrit, S.; Joblin, Ch.; Benz, A. O.; Boulanger, F.; Fuente, A.; Güsten, R.; Harris, A.; Klein, T.; Kramer, C.; Lord, S.; Martin, P.; Martin-Pintado, J.; Neufeld, D.; Phillips, T. G.; Röllig, M.; Simon, R.; Stutzki, J.; van der Tak, F.; Teyssier, D.; Yorke, H.; Erickson, N.; Fich, M.; Jellema, W.; Marston, A.; Risacher, C.; Salez, M.; Schmülling, F.

    2010-01-01

    We report the first detection of the ground-state rotational transition of the methylidyne cation CH+ towards the massive star-forming region DR 21 with the HIFI instrument onboard the Herschel satellite. The line profile exhibits a broad emission line, in addition to two deep and broad absorption f

  6. Strong CH+ J=1-0 emission and absorption in DR21

    NARCIS (Netherlands)

    Falgarone, E.; Ossenkopf, V.; Gerin, M.; Lesaffre, P.; Godard, B.; Pearson, J.; Cabrit, S.; Joblin, Ch; Benz, A. O.; Boulanger, F.; Fuente, A.; Güsten, R.; Harris, A.; Klein, T.; Kramer, C.; Lord, S.; Martin, P.; Martin-Pintado, J.; Neufeld, D.; Phillips, T. G.; Röllig, M.; Simon, R.; Stutzki, J.; van der Tak, F.; Teyssier, D.; Yorke, H.; Erickson, N.; Fich, M.; Jellema, W.; Marston, A.; Risacher, C.; Salez, M.; Schmülling, F.

    2010-01-01

    We report the first detection of the ground-state rotational transition of the methylidyne cation CH+ towards the massive star-forming region DR 21 with the HIFI instrument onboard the Herschel satellite. The line profile exhibits a broad emission line, in addition to two deep and broad absorption f

  7. HIFI observations of warm gas in DR21 : Shock versus radiative heating

    NARCIS (Netherlands)

    Ossenkopf, Volker; Roellig, M.; Simon, R.; Schneider, N.; Okada, Y.; Stutzki, J.; Gerin, M.; Akyilmaz, M.; Beintema, D; Benz, A. O.; Berne, O.; Boulanger, F.; Bumble, B.; Coeur-Joly, O.; Dedes, C.; Diez-Gonzalez, M. C.; France, K.; Fuente, A.; Gallego, J. D.; Goicoechea, J. R.; Guesten, R.; Harris, A.; Higgins, R.; Jackson, B.; Jarchow, C.; Joblin, C.; Klein, T.; Kramer, C.; Lord, S.; Martin, P.; Martin-Pintado, J.; Mookerjea, B.; Neufeld, D. A.; Phillips, T.; Rizzo, J. R.; van der Tak, F. F. S.; Teyssier, D.; Yorke, H.

    2010-01-01

    Context. The molecular gas in the DR21 massive star formation region is known to be affected by the strong UV field from the central star cluster and by a fast outflow creating a bright shock. The relative contribution of both heating mechanisms is the matter of a long debate. Aims. By better sampli

  8. Identifikasi Cysticercus bovis pada Steak Daging Sapi di Rumah Makan Jalan Dr. Mansyur Medan Tahun 2013

    OpenAIRE

    Humaidi, Nur Qistina

    2015-01-01

    Cysticercus bovis merupakan larva cacing pita Taenia saginata. Larva ini dapat menyebabkan taeniasis saginata. Taeniasis terjadi apabila manusia mengkonsumsi daging mentah atau dimasak kurang matang yang telah terkontaminasi Cysticercus bovis. Penilitian ini bertujuan untuk mengidentifikasi Cysticercus bovis pada steak daging sapi di rumah makan Jalan Dr. Mansyur, Medan. Jenis penelitian deskriptif dengan desain cross sectional. Penelitian ini menggunakan metode total sam...

  9. The First Data Release (DR1) of the LAMOST general survey

    CERN Document Server

    Luo, A -L; Zhao, G; Deng, L -C; Liu, X -W; Jing, Y -P; Wang, G; Zhang, H -T; Shi, J -R; Cui, X -Q; Chu, Y -Q; Li, G -P; Bai, Z -R; Cai, Y; Cao, S -Y; Cao, Z -H; Carlin, J L; Chen, H Y; Chen, J -J; Chen, K -X; Chen, L; Chen, X -L; Chen, X -Y; Chen, Y; Christlieb, N; Chu, J -R; Cui, C -Z; Dong, Y -Q; Du, B; Fan, D -W; Feng, L; Fu, J -N; Gao, P; Gong, X -F; Gu, B -Z; Guo, Y -X; Han, Z -W; He, B -L; Hou, J -L; Hou, Y -H; Hou, W; Hu, H -Z; Hu, N -S; Hu, Z -W; Huo, Z -Y; Jia, L; Jiang, F -H; Jiang, X; Jiang, Z -B; Jin, G; Kong, X; Kong, X; Lei, Y -J; Li, A -H; Li, C -H; Li, G -W; Li, H -N; Li, J; Li, Q; Li, S; Li, S -S; Li, X -N; Li, Y; Li, Y -B; Li, Y -P; Liang, Y; Lin, C -C; Liu, C; Liu, G -R; Liu, G -Q; Liu, Z -G; Lu, W -Z; Luo, Y; Mao, Y -D; Newberg, H; Ni, J -J; Qi, Z -X; Qi, Y -J; Shen, S -Y; Shi, H -M; Song, J; Song, Y -H; Su, D -Q; Su, H -J; Tang, Z -H; Tao, Q -S; Tian, Y; Wang, D; Wang, D -Q; Wang, F -F; Wang, G -M; Wang, H; Wang, H -C; Wang, J; Wang, J -N; Wang, J -L; Wang, J -P; Wang, J -X; Wang, L; Wang, M -X; Wang, S -G; Wang, S -Q; Wang, X; Wang, Y -N; Wang, Y; Wang, Y -F; Wang, Y -F; Wei, P; Wei, M -Z; Wu, H; Wu, K -F; Wu, X -B; Wu, Y; Wu, Y Z; Xing, X -Z; Xu, L -Z; Xu, X -Q; Xu, Y; Yan, T -S; Yang, D -H; Yang, H -F; Yang, H -Q; Yang, M; Yao, Z -Q; Yu, Y; Yuan, H; Yuan, H -B; Yuan, H -L; Yuan, W -M; Zhai, C; Zhang, E -P; Zhang, H W; Zhang, J -N; Zhang, L -P; Zhang, W; Zhang, Y; Zhang, Y -X; Zhang, Z -C; Zhao, M; Zhou, F; Zhou, X; Zhu, J; Zhu, Y -T; Zou, S -C; Zuo, F

    2015-01-01

    The Large sky Area Multi-Object Spectroscopic Telescope (LAMOST) General Survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QSOs. Objects both in the pilot survey and the first year general survey are included in the LAMOST First Data Release (DR1). The pilot survey started in October 2011 and ended in June 2012, and the data have been released to the public as the LAMOST Pilot Data Release in August 2012. The general survey started in September 2012, and completed its first year of operation in June 2013. The LAMOST DR1 includes a total of 1202 plates containing 2,955,336 spectra, of which 1,790,879 spectra have observed signal-to-noise S/N >10. All data with S/N>2 are formally released as LAMOST DR1 under the LAMOST data policy. This data release contains a total of 2,204,696 spectra, of which 1,944,329 are stellar spectra, 12,082 are galaxy spectra and 5,017 are quasars. The DR1 includes not only spect...

  10. The Galaxy Kinematics from OB Stars with Proper Motions from the Gaia DR1 Catalog

    CERN Document Server

    Bobylev, V V

    2016-01-01

    We consider two previously studied samples of OB stars with different distance scales. The first one consists of 98 massive spectroscopic binary stars with photometric distances, and the second one consists on 140 OB stars with the distances determined along the lines of interstellar calcium. The OB stars are located at distances up to 7 kpc from the Sun. They are identified with the Gaia DR1 catalog. It is shown that the use of the proper motions, taken from the Gaia DR1 catalog, allows to reduce random errors of determination of the Galactic rotation parameters in comparison with the previously known ones. From the analysis of 208 OB stars from the Gaia DR1 catalog with proper motions and parallaxes with relative errors less than 200% we found the Galactic kinematic parameters. In addition the Galactic rotation parameters were obtained from only line-of-sight velocities of the same stars. From the comparison of the two values of \\Omega^{'}_0 a distance scale of the Gaia DR1 catalog was determined as a value...

  11. Global transcriptome and physiological responses of Acinetobacter oleivorans DR1 exposed to distinct classes of antibiotics.

    Directory of Open Access Journals (Sweden)

    Aram Heo

    Full Text Available The effects of antibiotics on environment-originated nonpathogenic Acinetobacter species have been poorly explored. To understand the antibiotic-resistance mechanisms that function in nonpathogenic Acinetobacter species, we used an RNA-sequencing (RNA-seq technique to perform global gene-expression profiling of soil-borne Acinetobacter oleivorans DR1 after exposing the bacteria to 4 classes of antibiotics (ampicillin, Amp; kanamycin, Km; tetracycline, Tc; norfloxacin, Nor. Interestingly, the well-known two global regulators, the soxR and the rpoE genes are present among 41 commonly upregulated genes under all 4 antibiotic-treatment conditions. We speculate that these common genes are essential for antibiotic resistance in DR1. Treatment with the 4 antibiotics produced diverse physiological and phenotypic changes. Km treatment induced the most dramatic phenotypic changes. Examination of mutation frequency and DNA-repair capability demonstrated the induction of the SOS response in Acinetobacter especially under Nor treatment. Based on the RNA-seq analysis, the glyoxylate-bypass genes of the citrate cycle were specifically upregulated under Amp treatment. We also identified newly recognized non-coding small RNAs of the DR1 strain, which were also confirmed by Northern blot analysis. These results reveal that treatment with antibiotics of distinct classes differentially affected the gene expression and physiology of DR1 cells. This study expands our understanding of the molecular mechanisms of antibiotic-stress response of environment-originated bacteria and provides a basis for future investigations.

  12. In memorium Dr. Agatha Gijzen (1904-1995), eminent museum historian and zoo biologist

    NARCIS (Netherlands)

    Bruggen, van A.C.

    1996-01-01

    Dr Agatha Gijzen (Rotterdam *9 October 1904, Merksem/Belgium †19 February 1995) was a remarkable zoologist in more than one respect. Although her professional career, spanning more than three and a half decades, was largely spent as a staff zoologist in the service of the famous Antwerp/ Planckendae

  13. Advancing the Fundamental Understanding of Fission: 2014 LDRD 20120077DR Review

    Energy Technology Data Exchange (ETDEWEB)

    White, Morgan C. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Tovesson, Fredrik K. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Sierk, Arnold John [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-02-06

    The following slides were presented as part of the LDRD 20120077DR Progress Appraisal Review held Tuesday, February 4, 2014. This is part of an ongoing project assessment the previous of which was documented in LA-UR-13-21182. This presentation documents the progress made against the goals agreed to as part of the 2013 review.

  14. State Environmental Policy Act (SEPA) Checklist for the 105-DR Large Sodium Fire Facility Closure Plan

    Energy Technology Data Exchange (ETDEWEB)

    1990-09-01

    The Hanford Site, located northwest of the city of Richland, Washington, houses reactors, chemical-separation systems, and related facilities used for the production of special nuclear materials, as well as for activities associated with nuclear energy development. The 105-DR Large Sodium Fire Facility (LSFF), which was in operation from about 1972 to 1986, was a research laboratory that occupied the former ventilation supply room on the southwest side of the 105-DR Reactor facility. The LSFF was established to provide means of investigating fire and safety aspects associated with large sodium or other metal alkali fires in the liquid metal fast breeder reactor (LMFBR) facilities. The 105-DR Reactor facility was designed and built in the 1950's and is located in the 100-D Area of the Hanford Site. The building housed the DR defense reactor, which was shut down in 1964. The LSFF is subject to the regulatory requirements for the storage and treatment of dangerous wastes. Clean closure is the proposed method of closure for the LSFF. Closure will be conducted pursuant to the requirements of the Washington Administrative Code (WAC) 173-303-610 (Ecology 1989). This closure plan presents a description of the facility, the history of wastes managed, and the procedures that will be followed to close the LSFF as an Alkali Metal Treatment Facility. No future use of the LSFF is expected.

  15. Invent--Innovate--Implement--Interview with Dr. Christian Schaefer, Senior Vice President Sales, EV Group

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ Dr. Christian Schaefer, Senior Vice President Sales of EV Group, has 15 years of international management experience in the materials and equipment industry. During his tenure, Schaefer spearheaded the consolidation 9f RHI following the first Asian crisis and guided the company through major mergers and acquisitions,accomplishments that ultimately helped the company increase market share, revenues and profits.

  16. Dr. Kotnis Medical Team Performs Free Medical Service in Inner Mongolia

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    <正>The year 2010 is the birth centenary of Dr. Dwarkanath Kotnis, a great internationalist fighter who came to China as a member of the Indian Aid-China Medical Team in the 1930s, for which CPAFFC held a series of commemorative activities.

  17. Has the Dream Been Fulfilled? Dr. Martin Luther King, Jr. & President Barack Hussein Obama

    Science.gov (United States)

    Robinson, Nichelle Boyd; Moore, Virginia J.; Williams-Black, Thea H.

    2015-01-01

    Equality for all was the dream of Dr. Martin Luther King, Jr. and he knowingly laid the foundation for and inspired the first African-American President of the United States of America, Barack Hussein Obama, who also had the dream of "Change" for America. These men exhibited how working together can make dreams become reality. For the…

  18. Dr Malcolm King Honoured at University of Alberta Annual General Meeting

    Directory of Open Access Journals (Sweden)

    2004-01-01

    Full Text Available On September 25, 2003, Dr Malcolm King, former Canadian Thoracic Society (CTS President and member, was honoured by the University of Alberta (U of A with the University of Alberta Board of Governors Award of Distinction for 2003. The following are highlights of an article written by Ryan Smith for ExpressNews.

  19. Measurement of neutrophil membrane CD64 and HLA-Dr in a patient with abdominal sepsis.

    NARCIS (Netherlands)

    Meer, W. van der; Scott, C.S.; Verlaat, C.; Klein Gunnewiek, J.M.T.; Warris, A.

    2006-01-01

    A patient with abdominal sepsis, had both intra and extracellular bacteria in a blood smear, and high levels of neutrophil membrane CD64 and HLA-Dr. Intracellular bacteria are only observed in the terminal phase of a sepsis. Our patient recovered, suggesting that a high expression of neutrophil CD64

  20. If Dr. King Were a Principal: Building the "Beloved Community" in Schools

    Science.gov (United States)

    Hillis, Michael; Woolworth, Stephen

    2008-01-01

    In this article, the authors offer a more humanistic vision of educational community, one that is substantive in content yet flexible in its application to the diverse contexts in which American schooling occurs. In doing so, the authors turn specifically to the nonviolent philosophy of Dr. Martin Luther King, Jr. and consider what a school…

  1. On the nature of the WO3 star DR1 in IC 1613

    CERN Document Server

    Tramper, F; Hartoog, O E; Sana, H; de Koter, A; Vink, J S; Ellerbroek, L E; Langer, N; Garcia, M; Kaper, L; de Mink, S E

    2013-01-01

    We present the results of a quantitative spectroscopic analysis of the oxygen-sequence Wolf- Rayet star DR1 in the low-metallicity galaxy IC 1613. Our models suggest that the strong oxygen emission lines are the result of the high temperature of this WO3 star and do not necessarily reflect a more advanced evolutionary stage than WC stars.

  2. Validation of extraction, clean-up and DR CALUX {sup registered} bioanalysis. Pt. I. Feedingstuff

    Energy Technology Data Exchange (ETDEWEB)

    Besselink, H.; Jonas, A.; Brouwer, B. [BioDetection Systems BV (BDS), Amsterdam (Netherlands); Pijnappels, M.; Swinkels, A. [Masterlab BV, Boxmeer (Netherlands)

    2004-09-15

    Feed safety is a high priority issue for the feed sector as it directly impacts at the beginning of the food-chain. Currently stringent EU limit values are in force for dioxins in feedingstuffs for animal and public health protection. Biodetection Systems BV's (BDS) DR CALUX {sup registered} bioassay is a cost-effective and rapid method to measure low levels of dioxins and dioxin-like compounds in various matrices. The use of bioassays for monitoring dioxins in feed allows the (pre)-selection of samples suspected of being contaminated above limit values with dioxins. To permit bioassays to be used for screening feedingstuffs for the presence of dioxins and related compounds, the EU has laid down general requirements for the determination of dioxins and dioxin-like PCBs in feedingstuffs and specific requirements for cell-based bioassays. To ensure reliability the DR CALUX {sup registered} bioassay, validated methods for extraction and DR CALUX {sup registered} analysis are necessary. Within the framework of the development of DR CALUX {sup registered} analysis methods, extraction and clean-up methods for 13 feedingstuffs were evaluated, selected and validated. In this paper we present the results of this substantive multi-matrix feedingstuffs validation study.

  3. PlanetDR, a scalable architecture for federated repositories supporting IMS Learning Design

    NARCIS (Netherlands)

    Blat, Josep; Griffiths, David; Navarrete, Toni; Santos, José Luis; García, Pedro; Pujol, Jordi

    2006-01-01

    This paper discusses PlanetDR, whose architecture supports very large federated educational digital repositories. It is based on the implementation of current open specifications for interoperability (such as IEEE Learning Object Metadata and IMS Digital Repositories Interoperability, in its Edusour

  4. Report on Sabbatical activities - Dr. Ronnie Shepherd - 05/25/2014 to 08/21/2014

    Energy Technology Data Exchange (ETDEWEB)

    Shepherd, Ronnie [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2014-10-09

    The sabbatical performed by Dr. Ronnie Shepherd from 05/25/2014 to 08/21/2014 had two central goals: 1) write three proposals for future collaborative experiments at Ecole Polytechnique (and possibly LLNL) 2) if laser time was granted (based on the proposal), perform a preliminary experiment in preparation for the campaign of laser time based on proposal submission.

  5. VizieR Online Data Catalog: Comoving stars in Gaia DR1 (Oh+, 2017)

    Science.gov (United States)

    Oh, S.; Price-Whelan, A. M.; Hogg, D. W.; Morton, T. D.; Spergel, D. N.

    2017-08-01

    The primary data set used in this article is the Tycho-Gaia Astrometric Solution (TGAS), released as a part of Data Release 1 (DR1) of the Gaia mission (Gaia Collaboration et al. 2016, Cat. I/337; Lindegren et al. 2016A&A...595A...4L). (3 data files).

  6. Dr. Mary McLeod Bethune: A Life Devoted to Service

    Science.gov (United States)

    Long, Kim Cliett

    2011-01-01

    The purpose of this paper is to explore and analyze the leadership traits of Dr. Mary McLeod Bethune, an African-American woman of history, using the servant leadership theory developed by Robert K. Greenberg and the ten characteristics of servant leadership as conceived by Larry C. Spears. This exploration seeks to identify the significant…

  7. In memorium Dr. Agatha Gijzen (1904-1995), eminent museum historian and zoo biologist

    NARCIS (Netherlands)

    Bruggen, van A.C.

    1996-01-01

    Dr Agatha Gijzen (Rotterdam *9 October 1904, Merksem/Belgium †19 February 1995) was a remarkable zoologist in more than one respect. Although her professional career, spanning more than three and a half decades, was largely spent as a staff zoologist in the service of the famous Antwerp/

  8. Commemoration of Dr. Martin Luther King, Jr., January 15, 1929-April 4, 1968. Revised.

    Science.gov (United States)

    Montgomery County Public Schools, Rockville, MD.

    Developed in honor of Dr. Martin Luther King, Jr., this is a short collection of suggested activities to teach black awareness in the elementary and secondary grades through King's philosophy. An introductory biographical sketch of King and an article about his accomplishments are provided. Activities are divided into grade-level ranges for the…

  9. Fighting Fair. Dr. Martin Luther King, Jr. for Kids. Second Edition.

    Science.gov (United States)

    Schmidt, Fran; Friedman, Alice

    This curriculum guide for grades 4 through 9 uses the life and work of Dr. Martin Luther King, Jr., to teach conflict resolution and to explore the philosophy of non-violence for daily life. To enable students to learn and apply non-violence, it must be modeled in a classroom environment that builds trust and a sense of community. Each of the…

  10. Development and discrimination of 12 double ditelosomics in tetraploid wheat cultivar DR147.

    Science.gov (United States)

    Li, Hao; Wang, Changyou; Fu, Shulan; Guo, Xiang; Yang, Baoju; Chen, Chunhuan; Zhang, Hong; Wang, Yajuan; Liu, Xinlun; Han, Fangpu; Ji, Wanquan

    2014-02-01

    As an important group in Triticum, tetraploid wheat plays a significant role in the research of wheat evolution. Several complete aneuploid sets of common wheat have provided valuable tools for genetic and breeding studies, while similar aneuploids of tetraploid wheat are still not well developed. Here, 12 double ditelosomics developed in Triticum turgidum L. var. durum cultivar DR147 (excluding dDT2B and dDT3A) were reported. Hybrids between DR147 and the original double-ditelosomic dDT2B of Langdon lost vigor and died prematurely after the three-leaf stage; therefore, the dDT2B line was not obtained. The cytogenetic behaviors and phenotypic characteristics of each line were detailedly described. To distinguish the entire chromosome complement of tetraploid wheat, the DR147 karyotype was established by fluorescence in situ hybridization (FISH), using the Aegilops tauschii clone pAsl and the barley clone pHvG38 as probes. FISH using a cereal-specific centromere repeat (6C6) probe suggested that all the lines possessed four telosomes, except for 4AS of double-ditelosomic dDT4A, which carried a small segment of the long arm. On the basis of the idiogram of DR147, these lines were successfully discriminated by FISH using the probes pAsl and pHvG38 and were then accurately designated.

  11. Post-Disaster Image Processing for Damage Analysis Using GENESI-DR, WPS and Grid Computing

    Directory of Open Access Journals (Sweden)

    Marco Pappalardo

    2011-06-01

    Full Text Available The goal of the two year Ground European Network for Earth Science Interoperations-Digital Repositories (GENESI-DR project was to build an open and seamless access service to Earth science digital repositories for European and world-wide science users. In order to showcase GENESI-DR, one of the developed technology demonstrators focused on fast search, discovery, and access to remotely sensed imagery in the context of post-disaster building damage assessment. This paper describes the scenario and implementation details of the technology demonstrator, which was developed to support post-disaster damage assessment analyst activities. Once a disaster alert has been issued, response time is critical to providing relevant damage information to analysts and/or stakeholders. The presented technology demonstrator validates the GENESI-DR project data search, discovery and security infrastructure and integrates the rapid urban area mapping and the near real-time orthorectification web processing services to support a post-disaster damage needs assessment analysis scenario. It also demonstrates how the GENESI-DR SOA can be linked to web processing services that access grid computing resources for fast image processing and use secure communication to ensure confidentiality of information.

  12. Dr. Ruta Kruuda fond andis välja esimesed stipendiumid

    Index Scriptorium Estoniae

    2006-01-01

    Poliitikauuringute Keskuse PRAXIS juurde loodud dr Ruta Kruuda fond andis 10. märtsil 2006. a. välja oma esimesed stipendiumid, mille said Tervise Arengu Instituudi teadur Riina Raudne ja Tartu Ülikooli magistrand Liina Raju. Tema magistritöö keskendub HIV-nakkuse ja AIDSi teema kui avaliku arutelu objekti käsitlusele Eestis

  13. Dr. Richard D. Gragg III to Receive Third Place Gulf Guardian Award in the Individual Category

    Science.gov (United States)

    ATLANTA - Today, the Gulf of Mexico Program announced that Dr. Richard D. Schulterbrandt Gragg III will receive a Third Place 2015 Gulf Guardian Award in the Individual Category. The award will be given tonight at an awards ceremony at the Texas State Aqua

  14. How Dr Math reaches pupils with competitions and computer games by using MXit

    CSIR Research Space (South Africa)

    Butgereit, L

    2009-05-01

    Full Text Available In a world where school books, pencils and paper have to compete with cell phones, IPODs, and MP3 players for pupils' attention, Dr Math entices pupils to practice basic mathematics skills by providing games and competitions using Mxit over cell...

  15. Life and work of Dr. Johannes Govertus de Man (1850-1930)

    NARCIS (Netherlands)

    Karssen, G.

    2006-01-01

    This book describes the life and work of Dr. Johannes Govertus de Man (1850-1930), a remarkable Dutch invertebrate zoologist. J.G. de Man worked on the systematics of both the Crustacea, in particular on Decapoda (i.e. crabs, crayfish, lobsters and shrimps), and the microscopically Nematoda or

  16. It Really Is All about the Child: An Interview with Dr. Edward Hallowell

    Science.gov (United States)

    Peters, Dane L.

    2012-01-01

    In a decade when brain research has helped people understand learning difficulties in children, and people have seen increased media attention on the use of medications to treat attention deficit/hyperactivity disorder (ADHD) in children and adults, Dr. Edward (Ned) Hallowell has worked tirelessly to educate the medical profession, parents,…

  17. Identification of amino acids in the Dr adhesin required for binding to decay-accelerating factor.

    Science.gov (United States)

    Van Loy, Cristina P; Sokurenko, Evgeni V; Samudrala, Ram; Moseley, Steve L

    2002-07-01

    Members of the Dr family of adhesins of Escherichia coli recognize as a receptor the Dr(a) blood-group antigen present on the complement regulatory and signalling molecule, decay-accelerating factor (DAF). One member of this family, the Dr haemagglutinin, also binds to a second receptor, type IV collagen. Structure/function information regarding these adhesins has been limited and domains directly involved in the interaction with DAF have not been determined. We devised a strategy to identify amino acids in the Dr haemagglutinin that are specifically involved in the interaction with DAF. The gene encoding the adhesive subunit, draE, was subjected to random mutagenesis and used to complement a strain defective for its expression. The resulting mutants were enriched and screened to obtain those that do not bind to DAF, but retain binding to type IV collagen. Individual amino acid changes at positions 10, 63, 65, 75, 77, 79 and 131 of the mature DraE sequence significantly reduced the ability of the DraE adhesin to bind DAF, but not collagen. Over half of the mutants obtained had substitutions within amino acids 63-81. Analysis of predicted structures of DraE suggest that these proximal residues may cluster to form a binding domain for DAF.

  18. Dr.Shang Zhaokui's Experience in Acupuncture Treatment of Three Obstinate Cases

    Institute of Scientific and Technical Information of China (English)

    尚军

    2004-01-01

    @@ Dr. Shang Zhaokui (尚兆奎) has accumulated a wealth of experience in the acupuncture treatment of obstinate diseases in his clinical practice for more than 30 years. The following are three examples I would like to share with my colleagues.

  19. Why We Do Not Have Ethical Conduct: A Response to Dr. Sternberg

    Science.gov (United States)

    Carson, Jamin

    2014-01-01

    In "We Need to Teach for Ethical Conduct," Dr. Robert Sternberg argued that students act unethically because they are unable to transfer principles of ethics into practice. While I agree that this is partially the case, it is also the case that unethical behavior is a result of the prevailing educational-philosophy: radical…

  20. Water plant modifications for increased production at B, C, D, DR, F, and H Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Brinkman, L.B.; Corley, J.P.

    1960-04-15

    The purpose of this report is to define the extent of modifications necessary to increase capacities of the 100-B, C, D, DR, F, and H water plants for reactor flows of 90,000 95,000 105,000 and 115,000 GPM, and to provide supporting data for budget studies for increased production.

  1. Dr. Chang Min Chueh——Father of Test Tube Babies

    Institute of Scientific and Technical Information of China (English)

    1994-01-01

    CHANG Min Chueh (1908-1991)—the father of test tube babies, was a Chinese-born American scientist and inventor who developed the first oral contraceptives. Dr. Chang was from Dunhou Township, Lanxian County, Shanxi Province. In middle school, he was fascinated with biology. Later he was accepted to the Animal Psychology Department at Qinghua University.

  2. Photographer: Digital Telepresence: Dr Murial Ross's Virtual Reality Application for Neuroscience

    Science.gov (United States)

    1995-01-01

    Photographer: Digital Telepresence: Dr Murial Ross's Virtual Reality Application for Neuroscience Research Biocomputation. To study human disorders of balance and space motion sickness. Shown here is a 3D reconstruction of a nerve ending in inner ear, nature's wiring of balance organs.

  3. Neue Phoriden aus Belgisch-Kongo, gesammelt von Dr. Jos. Bequaert

    NARCIS (Netherlands)

    Schmitz, H.

    1916-01-01

    Durch die Güte des Herrn Dr. Jos. Bequaert konnte ich einige Phoriden untersuchen, die dieser eifrige Entomologe während seines letzten Aufenthalts am Kongo und im Ruwenzori-Gebirge gesammelt hat. Es lagen im ganzen 5 Arten vor, darunter zwei neue, die im folgenden beschrieben werden. Von den drei b

  4. If Dr. King Were a Principal: Building the "Beloved Community" in Schools

    Science.gov (United States)

    Hillis, Michael; Woolworth, Stephen

    2008-01-01

    In this article, the authors offer a more humanistic vision of educational community, one that is substantive in content yet flexible in its application to the diverse contexts in which American schooling occurs. In doing so, the authors turn specifically to the nonviolent philosophy of Dr. Martin Luther King, Jr. and consider what a school…

  5. Putting Functional Behavioral Assessment into Practice: A Conversation with Dr. Richard Van Acker.

    Science.gov (United States)

    Bullock, Lyndal M.; Gable, Robert A.

    1999-01-01

    In this interview, Dr. Richard Van Acker discusses federal requirements for functional behavioral assessments (FBAs) and the teamwork involved in conducting an FBA. Various components of FBAs and the approximate time required are outlined and examples are provided of structured data collection for use in the FBA. (CR)

  6. HUCKLEBERRY FINN. DR. JEKYLL AND MR. HYDE. SHORT STORIES. LITERATURE CURRICULUM IV, STUDENT VERSION.

    Science.gov (United States)

    KITZHABER, ALBERT R.

    A STUDENT'S CURRICULUM GUIDE FOR THE STUDY OF "HUCKLEBERRY FINN,""DR. JEKYLL AND MR. HYDE," AND THREE SHORT STORIES WAS PRESENTED. THE SHORT STORIES INCLUDED WERE (1) "THE COUNTRY OF THE BLIND" BY H.G. WELLS (COMPLETE TEXT), (2) "A DOUBLE-DYED DECEIVER" BY O. HENRY, AND (3) "A MYSTERY OF HEROISM"…

  7. HUCKLEBERRY FINN. DR. JEKYLL AND MR. HYDE. SHORT STORIES. LITERATURE CURRICULUM IV, TEACHER VERSION.

    Science.gov (United States)

    KITZHABER, ALBERT R.

    A CURRICULUM GUIDE FOR THE TEACHING OF "HUCKLEBERRY FINN,""DR. JEKYLL AND MR. HYDE," AND FOUR SHORT STORIES WAS PRESENTED. THE SHORT STORIES WERE (1) "THE APPLE TREE" BY JOHN GALSWORTHY, (2) "THE COUNTRY OF THE BLIND" BY H.G. WELLS, (3) "A DOUBLE-DYED DECEIVER" BY O. HENRY, AND (4) "A MYSTERY…

  8. LITERATURE CURRICULUM IV--TESTS FOR "HUCKLEBERRY FINN" AND "DR. JEKYLL AND MR. HYDE."

    Science.gov (United States)

    KITZHABER, ALBERT R.

    THESE TWO TESTS--"HUCKLEBERRY FINN" AND "DR. JEKYLL AND MR. HYDE"--WERE DESIGNED BY THE OREGON CURRICULUM STUDY CENTER FOR A 10TH-GRADE LITERATURE CURRICULUM. THEY ARE INTENDED TO ACCOMPANY CURRICULUM UNITS AVAILABLE AS ED 010 821 AND ED 010 822. (MM)

  9. Drømmen om den perfekte målestok

    DEFF Research Database (Denmark)

    Mehlsen, Camilla; Pedersen, Peder Holm

    2010-01-01

    Uddannelsespolitikere og -forskere drømmer om at skabe en international målestok og fælles standarder for uddannelse. Men kan uddannelse måles, og er det en fordel, at de nationale uddannelsessystemer harmoniseres, når en nations konkurrencekraft hviler på det, der adskiller den fra andre nationer?...

  10. Has the Dream Been Fulfilled? Dr. Martin Luther King, Jr. & President Barack Hussein Obama

    Science.gov (United States)

    Robinson, Nichelle Boyd; Moore, Virginia J.; Williams-Black, Thea H.

    2015-01-01

    Equality for all was the dream of Dr. Martin Luther King, Jr. and he knowingly laid the foundation for and inspired the first African-American President of the United States of America, Barack Hussein Obama, who also had the dream of "Change" for America. These men exhibited how working together can make dreams become reality. For the…

  11. Neue Phoriden aus Belgisch-Kongo, gesammelt von Dr. Jos. Bequaert

    NARCIS (Netherlands)

    Schmitz, H.

    1916-01-01

    Durch die Güte des Herrn Dr. Jos. Bequaert konnte ich einige Phoriden untersuchen, die dieser eifrige Entomologe während seines letzten Aufenthalts am Kongo und im Ruwenzori-Gebirge gesammelt hat. Es lagen im ganzen 5 Arten vor, darunter zwei neue, die im folgenden beschrieben werden. Von den drei

  12. Connect the Book. Martin's Big Words: The Life of Dr. Martin Luther King, Jr.

    Science.gov (United States)

    Brodie, Carolyn S.

    2005-01-01

    In honor of Martin Luther King, Jr. Day, this month's featured book is "Martin's Big Words: The Life of Dr. Martin Luther King, Jr." The book was written by Doreen Rappaport and illustrated by Bryan Collier (Jump at the Sun, 2001. 40p. ISBN 0786807148). This pictorial biography of the world-renowned civil rights leader has one of the most striking…

  13. Dr. Ruta Kruuda fond andis välja esimesed stipendiumid

    Index Scriptorium Estoniae

    2006-01-01

    Poliitikauuringute Keskuse PRAXIS juurde loodud dr Ruta Kruuda fond andis 10. märtsil 2006. a. välja oma esimesed stipendiumid, mille said Tervise Arengu Instituudi teadur Riina Raudne ja Tartu Ülikooli magistrand Liina Raju. Tema magistritöö keskendub HIV-nakkuse ja AIDSi teema kui avaliku arutelu objekti käsitlusele Eestis

  14. Prof. Dr. Steven Leow Yoon Loy: New Revolution Leader in Asian Marketing

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ A lock of goldenly dyed hair makes Prof. Dr. Steven Leow looked cool and special compared with other entrepreneurs. In fact,he is extraordinary not only in the appearance but also in his style of management, always creative and resourceful.

  15. Computer control system for sup 6 sup 0 Co industrial DR nondestructive testing system

    CERN Document Server

    Chen Hai Jun

    2002-01-01

    The author presents the application of sup 6 sup 0 Co industrial DR nondestructive testing system, which including the control of step-motor, electrical protection, computer monitor program. The computer control system has good performance, high reliability and cheap expense

  16. Dr Math moves to C³TO: Chatter call center/tutoring online

    CSIR Research Space (South Africa)

    Butgereit, L

    2010-01-01

    Full Text Available Dr Math is a mobile tutoring system which has been running in South Africa for three years. It links primary and secondary school pupils to tutors in mathematics. The pupils use the popular Mxit chat client on their cell phones. The tutors use full...

  17. Dr. Anna Julia Cooper, 1858-1964: Teacher, Scholar, and Timeless Womanist

    Science.gov (United States)

    Giles, Mark S.

    2006-01-01

    The study examines the various accomplishments and achievements of Dr. Anna Julia Cooper, a social activist-educator, scholar and an early model for African-American feminist theory. Cooper was a great public intellectual and teacher, as she highly attacked the prevalence of racism, sexism and poverty through her writings and by working with…

  18. African American Women Scholars and International Research: Dr. Anna Julia Cooper's Legacy of Study Abroad

    Science.gov (United States)

    Evans, Stephanie Y.

    2009-01-01

    EIn this article, the author presents a little-known but detailed history of Black women's tradition of study abroad. Specifically, she situates Dr. Anna Julia Cooper within the landscape of historic African American students who studied in Japan, Germany, Jamaica, England, Italy, Haiti, India, West Africa, and Thailand, in addition to France. The…

  19. From the Field: Speech Therapy Outcome Measures--Interview with Dr. Pam Enderby

    Science.gov (United States)

    Montgomery, Judy K.

    2015-01-01

    This article is an interview with Dr. Pam Enderby--a speech language therapist and professor at the Institute of General Practice and Primary Care at the University of Sheffield, Community Sciences Centre, Northern General Hospital, in the United Kingdom--conducted by Judy Montgomery, Editor in Chief, of "Communication Disorders…

  20. Dr William Thornton (1759-1828) a savant of colonial America.

    Science.gov (United States)

    Schneeberg, Norman G

    2006-08-01

    Dr William Thornton, an Edinburgh-trained physician, practised medicine sporadically in the British West Indies, the location of his birthplace, and in Philadelphia during post-revolutionary Colonial America. He is not well known to medical historians and 21st century physicians and is remembered principally as the amateur architect who designed the Capitol in Washington, DC and the Library Company of Philadelphia.

  1. Mutations Enhancing Selectivity of Antitumor Cytokine TRAIL to DR5 Receptor Increase Its Cytotoxicity against Tumor Cells.

    Science.gov (United States)

    Gasparian, M E; Bychkov, M L; Yagolovich, A V; Dolgikh, D A; Kirpichnikov, M P

    2015-08-01

    Tumor necrosis factor superfamily cytokine TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) induces apoptosis in tumor cells by binding to death receptors DR4 and DR5 without affecting normal cells. However, the therapeutic use of TRAIL is limited, because many tumor cells are resistant to it. The resistance is partially related to interaction of TRAIL with the decoy receptors DcR1 and DcR2, which do not trigger the apoptotic signal and inhibit signaling of death receptors. Previously, we designed a unique DR5-specific TRAIL mutant variant DR5-B, which binds to DR5 receptor as effectively as the original cytokine, but has practically no interaction with DR4 and DcR1 receptors, and its affinity for DcR2 is reduced 400-fold. In the present work, the cytotoxity of TRAIL and DR5-B was analyzed on 12 different tumor cell lines and two types of normal cells. In nine of 12 tumor cell lines, DR5-B killed 1.5-5.0 times more tumor cells than TRAIL, and it did not exhibit toxicity towards normal cells. Chemotherapeutic drugs such as doxorubicin, paclitaxel, and bortezomib augmented the effect of both TRAIL variants, and the enhancing effect was more pronounced for DR5-B. Half-maximal effective concentrations (EC50) for DR5-B in combination with chemotherapeutic agents were 1.5-10.0 times lower than for wild-type TRAIL. Thus, DR5-B is a promising candidate both for monotherapy and in combination with chemotherapy for treatment of TRAIL-resistant tumors.

  2. Generation of functional HLA-DR*1101 tetramers receptive for loading with pathogen or tumour derived synthetic peptides

    Directory of Open Access Journals (Sweden)

    Protti Maria

    2005-12-01

    Full Text Available Abstract Background MHC class I-peptide tetramers are currently utilised to characterize CD8+ T cell responses at single cell level. The generation and use of MHC class II tetramers to study antigen-specific CD4+ T cells appears less straightforward. Most MHC class II tetramers are produced with a homogeneously built-in peptide, reducing greatly their flexibility of use. We attempted the generation of "empty" functional HLA-DR*1101 tetramers, receptive for loading with synthetic peptides by incubation. No such reagent is in fact available for this HLA-DR allele, one of the most frequent in the Caucasian population. Results We compared soluble MHC class II-immunoglobulin fusion proteins (HLA-DR*1101-Ig with soluble MHC class II protein fused with an optimised Bir site for enzymatic biotynilation (HLA-DR*1101-Bir, both produced in insect cells. The molecules were multimerised by binding fluorochrome-protein A or fluorochrome-streptavidin, respectively. We find that HLA-DR*1101-Bir molecules are superior to the HLA-DR*1101-Ig ones both in biochemical and functional terms. HLA-DR*1101-Bir molecules can be pulsed with at least three different promiscuous peptide epitopes, derived from Tetanus Toxoid, influenza HA and the tumour associated antigen MAGE-3 respectively, to stain specific CD4+ T cells. Both staining temperature and activation state of CD4+ T cells are critical for the binding of peptide-pulsed HLA-DR*1101-Bir to the cognate TCR. Conclusion It is therefore possible to generate a soluble recombinant HLA-DR*1101 backbone that is receptive for loading with different peptides to stain specific CD4+ T cells. As shown for other HLA-DR alleles, we confirm that not all the strategies to produce soluble HLA-DR*1101 multimers are equivalent.

  3. TEPITOPEpan: extending TEPITOPE for peptide binding prediction covering over 700 HLA-DR molecules.

    Directory of Open Access Journals (Sweden)

    Lianming Zhang

    Full Text Available MOTIVATION: Accurate identification of peptides binding to specific Major Histocompatibility Complex Class II (MHC-II molecules is of great importance for elucidating the underlying mechanism of immune recognition, as well as for developing effective epitope-based vaccines and promising immunotherapies for many severe diseases. Due to extreme polymorphism of MHC-II alleles and the high cost of biochemical experiments, the development of computational methods for accurate prediction of binding peptides of MHC-II molecules, particularly for the ones with few or no experimental data, has become a topic of increasing interest. TEPITOPE is a well-used computational approach because of its good interpretability and relatively high performance. However, TEPITOPE can be applied to only 51 out of over 700 known HLA DR molecules. METHOD: We have developed a new method, called TEPITOPEpan, by extrapolating from the binding specificities of HLA DR molecules characterized by TEPITOPE to those uncharacterized. First, each HLA-DR binding pocket is represented by amino acid residues that have close contact with the corresponding peptide binding core residues. Then the pocket similarity between two HLA-DR molecules is calculated as the sequence similarity of the residues. Finally, for an uncharacterized HLA-DR molecule, the binding specificity of each pocket is computed as a weighted average in pocket binding specificities over HLA-DR molecules characterized by TEPITOPE. RESULT: The performance of TEPITOPEpan has been extensively evaluated using various data sets from different viewpoints: predicting MHC binding peptides, identifying HLA ligands and T-cell epitopes and recognizing binding cores. Among the four state-of-the-art competing pan-specific methods, for predicting binding specificities of unknown HLA-DR molecules, TEPITOPEpan was roughly the second best method next to NETMHCIIpan-2.0. Additionally, TEPITOPEpan achieved the best performance in

  4. Generation of human MHC (HLA-A11/DR1) transgenic mice for vaccine evaluation

    Science.gov (United States)

    Zeng, Yang; Gao, Tongtong; Zhao, Guangyu; Jiang, Yuting; Yang, Yi; Yu, Hong; Kou, Zhihua; Lone, Yuchun; Sun, Shihui; Zhou, Yusen

    2016-01-01

    ABSTRACT The rapid occurrence of emerging infectious diseases demonstrates an urgent need for a new preclinical experimental model that reliably replicates human immune responses. Here, a new homozygous humanized human leukocyte antigen (HLA)-A11/DR1 transgenic mouse (HLA-A11+/+/DR01+/+/H-2-β2m−/−/IAβ−/−) was generated by crossing HLA-A11 transgenic (Tg) mice with HLA-A2+/+/DR01+/+/H-2-β2m−/−/IAβ−/− mice. The HLA-A11-restricted immune response of this mouse model was then examined. HLA-A11 Tg mice expressing a chimeric major histocompatibility complex (MHC) molecule comprising the α1, α2, and β2m domains of human HLA-A11 and the α3 transmembrane and cytoplasmic domains of murine H-2Db were generated. The correct integration of HLA-A11 and HLA-DR1 into the genome of the HLA-A11/DR1 Tg mice (which lacked the expression of endogenous H-2-I/II molecules) was then confirmed. Immunizing mice with a recombinant HBV vaccine or a recombinant HIV-1 protein resulted in the generation of IFN-γ-producing cytotoxic T lymphocyte (CTL) and antigen-specific antibodies. The HLA-A11-restricted CTL response was directed at HLA immunodominant epitopes. These mice represent a versatile animal model for studying the immunogenicity of HLA CTL epitopes in the absence of a murine MHC response. The established animal model will also be useful for evaluating and optimizing T cell-based vaccines and for studying differences in antigen processing between mice and humans. PMID:26479036

  5. I distrust self-declared patent solutions. Interview with Dr. Angela Merkel, Federal Minister of the Environment; Mich stoeren vermeintliche Patentrezepte. Interview mit Bundesumweltministerin Dr. Angela Merkel

    Energy Technology Data Exchange (ETDEWEB)

    Merkel, A. [Bundesministerium fuer Umwelt, Naturschutz und Reaktorsicherheit, Bonn (Germany); Roehrlich, D.

    1995-12-31

    Dr. Merkel answered questions on energy supply and environmental protection. The following subjects were discussed: Efficient use of energy, legal regulations, energy mix, developments in nuclear technology, better acceptance of renewable energy sources, nuclear phase-out - not a feasible alternative, increasing acceptance of waste incineration plants. (BWI) [Deutsch] Der vorliegende Beitrag gibt ein Interview mit der Bundesumweltministerin Merkel zu Fragen der Energieversorgung und des Umweltschutzes wider. In diesem Zusammenhang werden folgende Themenbereiche diskutiert: Effizientere Energienutzung, rechtliche Regelungen, Zusammensetzung der eingesetzten Energietraeger, Weiterentwicklung der Kerntechnologie, Abbau von Hemmnissen bei erneuerbaren Energiequellen, Verzicht auf Kernkraft nicht sinnvoll, zunehmende Akzeptanz fuer Muellverbrennungsanlagen. (BWI)

  6. Rational Emotive Behavioural Therapy: The Evolution of a Revolution: Interview With Dr. Debbie Joffe Ellis, Work Partner and Wife of Dr. Albert Ellis, the Creator of REBT.

    Science.gov (United States)

    Ellis, Debbie Joffe; Rovira, Montse

    2015-02-01

    Recognized as one of the most influential thinkers and psychologists, Albert Ellis PhD (1913-2007) revolutionized Psychology when he created the first cognitive psychotherapy, Rational Emotive Behavioral Therapy. After he passed away, Dr. Debbie Joffe Ellis continues spreading his legacy around the world. Psychologist, lecturer, writer, trainer, she dedicates her life to disseminate REBT and extend it through different statements, from the social to the educational, from the academic to the clinical. In this interview, she goes through her own history and her husband's one, bringing us closer to understanding Albert Ellis as the leading figure in his field, and the oneness they experienced through their professional and personal relationship.

  7. Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan

    DEFF Research Database (Denmark)

    Nielsen, Morten; Lundegaard, Claus; Blicher, Thomas

    2008-01-01

    class II molecules is therefore of pivotal importance for rational discovery of immune epitopes. HLA-DR is a prominent example of a human MHC class II. Here, we present a method, NetMHCIIpan, that allows for pan-specific predictions of peptide binding to any HLA-DR molecule of known sequence. The method...

  8. HLA-DR molecules enhance signal transduction through the CD3/Ti complex in activated T cells

    DEFF Research Database (Denmark)

    Odum, Niels; Martin, P J; Schieven, G L;

    1991-01-01

    Crosslinking HLA-DR molecules by monoclonal antibodies (mAb) induces protein tyrosine phosphorylation and results in a secondary elevation of free cytoplasmic Ca2+ concentration ([Ca2+]i) in activated human T cells. Here we have studied the effect of DR on CD3-induced signal transduction...

  9. Professional Development: What Works? Q&A with Dr. Hilda Borko. REL Mid-Atlantic Teacher Effectiveness Webinar Series

    Science.gov (United States)

    Regional Educational Laboratory Mid-Atlantic, 2013

    2013-01-01

    In this webinar, Dr. Hilda Borko, professor, Stanford University Graduate School of Education, presented examples of promising models of professional development, including the Problem-Solving Cycle, Learning and Teaching Geometry, and the use of videos as tools for teacher learning. This Q&A addressed the questions participants had for Dr.…

  10. Enhancing effect of tazarotene on the HLA-DR expression of cultured human keratinocytes induced by interferon-gamma

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jian-gan; TAN Sheng-shun

    2005-01-01

    Objective: To investigate the effect of tazarotene on the expression of HLA-DR induced by IFN-γ. Methods: (1) Keratinocytes from normal human skin were cultured in vitro;(2) Tazarotene, IFN-γ and the combination of the two compounds were incubated with the keratinocytes in medium, respectively. The expression of HLA-DR in keratinocytes was determined using immunocytochemistry techniques at 24h after incubation. Results: (1) There was rare expression of HLA-DR in normal human keratinocytes; (2) 10-6mol/L tazarotene failed to induce the expression of HLA-DR in keratinocytes at 24h after incubation; (3) 500 U/ml IFN-γ obviously induced the HLA-DR expression in keratinocytes at 24h after treatment; (4) After 24h, 10-7-10-5 mol/L tazarotene had a significantly enhancing effect on the expression of HLA-DR induced by IFN-γ (P<0.005). Conclusion: Tazarotene up-regulates the expression of HLA-DR in keratinocytes cultured in vitro when combined with IFN-γ . Therefore, the reduction of HLA-DR positive keratinocytes in psoriatic lesions may be attributed to not direct interaction of tazarotene in combination with IFN-γ but other pathways.

  11. HLA class II (DR, DQ, DP) in patients with sarcoidosis: evidence of an increased frequency of DRw6

    DEFF Research Database (Denmark)

    Ødum, Niels; Milman, N; Jakobsen, B K

    1991-01-01

    The distribution of HLA class II (DR, DQ, and DP) antigens was studied in 41 patients with symptomatic sarcoidosis (SA) and ethnically matched healthy controls. HLA-DR, -DQw1 and -DQw3 typings were performed with alloantisera in the conventional microcytotoxic test, whereas -DP typings were done...

  12. All I Really Need to Know I Learned in Kindergarten: How Dr. Seuss Reinforces Management Concepts and Promotes Community Citizenship

    Science.gov (United States)

    Comer, Debra R.; Holbrook, Robert L., Jr.

    2005-01-01

    The authors recommend that management educators add the works of Dr. Seuss to their repertoire of teaching tools. After describing why instructors should use Dr. Seuss's stories to foster understanding of concepts in management and organizational behavior, the authors describe a Seuss-based project at two levels that (a) helps students identify…

  13. HLA-DR polymorphism modulates response to house dust mites in a transgenic mouse model of airway inflammation.

    Science.gov (United States)

    Rajagopalan, G; Tilahun, A Y; Iijima, K; David, C S; Kita, H; Juhn, Y J

    2011-06-01

    We and others have reported that HLA-DRB1*03 is associated with childhood asthma. To extend this observation and to prove this association, we sensitized and challenged either HLA-DR2 (HLA-DRB1*1502) or HLA-DR3 (HLA-DRB1*0301) transgenic mice with house-dust mite extract. Inflammatory cell counts and cytokine levels in the bronchoalveolar lavage (BAL) fluid between HLA-DR3 and DR2 mice were compared. HLA-DR3 transgenic mice had significantly elevated eosinophil counts, Interleukin-4 and Interleukin-13 levels in the BAL fluid but not interferron gamma-γ. Thus, our study suggests that HLA-DRB1*0301 plays an important role in mounting a Th2-predominant immune response to house dust mite and Th2-type inflammation in the lung. © 2011 John Wiley & Sons A/S.

  14. Widespread Alu repeat-driven expansion of consensus DR2 retinoic acid response elements during primate evolution

    Directory of Open Access Journals (Sweden)

    Wang Tian-Tian

    2007-01-01

    Full Text Available Abstract Background Nuclear receptors are hormone-regulated transcription factors whose signaling controls numerous aspects of development and physiology. Many receptors recognize DNA hormone response elements formed by direct repeats of RGKTCA motifs separated by 1 to 5 bp (DR1-DR5. Although many known such response elements are conserved in the mouse and human genomes, it is unclear to which extent transcriptional regulation by nuclear receptors has evolved specifically in primates. Results We have mapped the positions of all consensus DR-type hormone response elements in the human genome, and found that DR2 motifs, recognized by retinoic acid receptors (RARs, are heavily overrepresented (108,582 elements. 90% of these are present in Alu repeats, which also contain lesser numbers of other consensus DRs, including 50% of consensus DR4 motifs. Few DR2s are in potentially mobile AluY elements and the vast majority are also present in chimp and macaque. 95.5% of Alu-DR2s are distributed throughout subclasses of AluS repeats, and arose largely through deamination of a methylated CpG dinucleotide in a non-consensus motif present in AluS sequences. We find that Alu-DR2 motifs are located adjacent to numerous known retinoic acid target genes, and show by chromatin immunoprecipitation assays in squamous carcinoma cells that several of these elements recruit RARs in vivo. These findings are supported by ChIP-on-chip data from retinoic acid-treated HL60 cells revealing RAR binding to several Alu-DR2 motifs. Conclusion These data provide strong support for the notion that Alu-mediated expansion of DR elements contributed to the evolution of gene regulation by RARs and other nuclear receptors in primates and humans.

  15. Cross-Correlation of SDSS DR7 Quasars and DR10 BOSS Galaxies: The Weak Luminosity Dependence of Quasar Clustering at z~0.5

    CERN Document Server

    Shen, Yue; White, Martin; Zheng, Zheng; Myers, Adam D; Guo, Hong; Kirkpatrick, Jessica A; Padmanabhan, Nikhil; Parejko, John K; Ross, Nicholas P; Schlegel, David J; Schneider, Donald P; Streblyanska, Alina; Swanson, Molly E C; Zehavi, Idit; Pan, Kaike; Bizyaev, Dmitry; Brewington, Howard; Ebelke, Garrett; Malanushenko, Viktor; Malanushenko, Elena; Oravetz, Daniel; Simmons, Audrey; Snedden, Stephanie

    2012-01-01

    We present the measurement of the two-point cross-correlation function (CCF) of 8,198 Sloan Digital Sky Survey (SDSS) Data Release 7 (DR7) quasars and 349,608 DR10 CMASS galaxies from the Baryonic Oscillation Spectroscopic Survey (BOSS) at redshift ~0.5 (0.3=0.53 from the CCF measurements. This linear bias corresponds to a characteristic host halo mass of ~4x10^12 M_sun/h, compared to ~10^13 M_sun/h characteristic host halo mass for CMASS galaxies. We divide the quasar sample in luminosity and constrain the luminosity dependence of quasar bias to be db_Q/dlogL=0.20+-0.34 or 0.11+-0.32 (depending on different luminosity divisions) for quasar luminosities -23.5>M_i(z=2)>-25.5, implying a weak luminosity dependence of quasar clustering for the bright end of the quasar population at ~0.5. We compare our measurements with theoretical predictions, Halo Occupation Distribution (HOD) models and mock catalogs. These comparisons suggest quasars reside in a broad range of host halos, and the host halo mass distributions...

  16. Profil Pasien Rinosinusitis Kronik di Poliklinik THT-KL RSUP DR.M.Djamil Padang

    Directory of Open Access Journals (Sweden)

    Hesty Trihastuti

    2015-09-01

    Full Text Available Abstrak Rinosinusitis kronik adalah inflamasi kronik pada mukosa hidung dan sinus paranasal yang sering terjadi, tetapi belum ada data mengenai profil pasien rinosinusitis kronik di RSUP Dr.M.Djamil Padang. Penelitian ini merupakan penelitian deskriptif dengan mengambil data rekam medis THT-KL RSUP Dr.M.Djamil periode 1 Januari – 31 Desember 2012 dengan metode total sampling. Terdapat 63 kasus rinosinusitis kronik di poliklinik THT-KL RSUP Dr.M.Djamil Padang periode 1 Januari – 31 Desember 2012. Kasus rinosinusitis kronik paling banyak terjadi pada kelompok usia 46 – 55 tahun (22,22% dan banyak terjadi pada perempuan (60,32%. Berdasarkan tanda dan gejala yang ditemukan paling banyak adalah deviasi septum (41,27%. Gejala klinik paling banyak adalah hidung tersumbat (88,89%. Berdasarkan pemeriksaan rinoskopi anterior dan nasoendoskopi ditemukan kelainan pada kavum nasi, konka inferior, konka media, dan sekret. Disimpulkan bahwa rinosinusitis kronik banyak terjadi pada usia dewasa, jenis kelamin perempuan, tanda dan gejala yang ditemukan deviasi septum, gejala berupa hidung tersumbat, sertaditemukan kelainan berdasarkan pemeriksaan rinoskopi anterior dan nasoendoskopi.Kata kunci: rinosinusitis kronik, pemeriksaan rinoskopi anterior, pemeriksaan nasoendoskopi AbstractChronic rhinosinusitis is a common chronic inflammation of the nose and paranasal sinuses mucosa, but there  is no data about profile of chronic rhinosinusitis patients at ENT clinic Dr.M.Djamil general hospital Padang. This research uses descriptive method by taking the data from the medical records at ENT clinic of Dr.M.Djamil general hospital during 1 January – 31 December 2012 with the method is total sampling. There are 63 chronic rhinosinusitis cases at ENT clinic Dr.M.Djamil Padang general hospital during 1 January – 31 December 2012. Most cases of chronic rhinosinusitis occurred in the age group 46 – 55 years old (22.22% and higher in female (60.32%. The most sign

  17. Dr. Eng

    OpenAIRE

    2012-01-01

    One problem in high-density environment such as in Lae Lae isle, Makassar-Indonesia is the unavailability of shared public space. Lae Lae isle, one small island in front of Makassar city is a densely populated, where 0.22 km2 is occupied by 1.563 people. Common sights in this isle are many people, all generations gathering on a bench in everywhere, and the bench called Bale bale. It is used by islander for private space and further change into shared place. The aims of this study are to ident...

  18. Objective measures of laryngeal imaging: what have we learned since Dr. Paul Moore.

    Science.gov (United States)

    Woo, Peak

    2014-01-01

    Dr. Paul Moore pioneered the use of high-speed cinematography for observation of normal and abnormal vocal fold vibrations during phonation. His analysis of the glottal area waveform, opening and closing speed index, and open quotient from the high-speed films were labor intensive but relevant today. With advances in digital image capture and automated image extraction techniques, stroboscopy and high-speed images of vocal fold vibration may be analyzed with objective measures. Digital high-speed image capture in color is now clinically practical at high resolution. Digital kymography now allows analysis of the vibratory waveform from each vocal fold. Serial capture and comparison can document changes in vibratory function with treatment. Quantification of vocal fold vibration using such techniques is now practical. This is a review of vocal fold vibration capture and analysis techniques since Dr. Moore.

  19. VizieR Online Data Catalog: VPHAS+ DR2 survey (Drew+, 2016)

    Science.gov (United States)

    Drew, J. E.; Gonzalez-Solares, E.; Greimel, R.; Irwin, M. J.; Kupcu Yoldas, A.; Lewis, J.; Barentsen, G.; Eisloffel, J.; Farnhill, H. J.; Martin, W. E.; Walsh, J. R.; Walton, N. A.; Mohr-Smith, M.; Raddi, R.; Sale, S. E.; Wright, N. J.; Groot, P.; Barlow, M. J.; Corradi, R. L. M.; Drake, J. J.; Fabregat, J.; Frew, D. J.; Gansicke, B. T.; Knigge, C.; Mampaso, A.; Morris, R. A. H.; Naylor, T.; Parker, Q. A.; Phillipps, S.; Ruhland, C.; Steeghs, D.; Unruh, Y. C.; Vink, J. S.; Wesson, R.; Zijlstra, A. A.

    2016-10-01

    The Second VPHAS data release (DR2) covers the first 21 months of data-taking in which the survey progressed to 24 percent completion. Much of the Galactic mid-plane is now covered (especially in the r, i and Hα filters). This release supersedes DR1. For access to the release documents and ESO archive entry, see ESO's public survey pages (http://eso.org/rm/publicAccess#/dataReleases). The appropriate journal reference for the use of VPHAS+data is to: Drew et al., 2014MNRAS.440.2036D. If making use of data from this release, please use the following statement in the acknowledgements: "Based on data products from observations made with ESO Telescopes at the La Silla Paranal Observatory under public survey programme ID, 177.D-3023". (1 data file).

  20. Thaumaleidae (Diptera) collected by the late Dr. W. Joost in the Caucasus Mountains.

    Science.gov (United States)

    Wagner, Rüdiger; Bellstedt, Ronald

    2015-11-05

    The aquatic insect collection of the late Dr. W. Joost contained two new species of Thaumaleidae (Diptera) from the Caucasus Mountains: Thaumalea monikae sp. n. and Thaumalea biacuminata sp. n. These two new species are herein described, and the most abundant species in Dr. Joost's collection, Thaumalea martinovskyi Joost, 1979, is redescribed based on the type material. Figures of male and female genitalia for all species are provided. All three species show morphological similarities to taxa from the Eastern Mediterranean area. Thaumalea monikae is related to the European T. bezzii-species group, T. biacuminata to the T. serrata-group, and T. martinovskyi to T. kyladica Wagner, 1981 and T. malickyi Theischinger, 1979 from the Eastern Mediterranean area.

  1. Isomerization and optical bistability of DR1 doped organic-inorganic sol-gel thin film

    Science.gov (United States)

    Gao, Tianxi; Que, Wenxiu; Shao, Jinyou

    2015-10-01

    To investigate the isomerization process of the disperse red 1 (DR1) doped TiO2/ormosil thin film, both the photo-isomerization and the thermal isomerization of the thin films were observed as a change of the absorption spectrum. Under a real-time heat treatment, the change of the linear refractive index shows a thermal stable working temperature range below Tg. The optical bistability (OB) effect of the DR1 doped thin films based on different matrices was studied and measured at a wavelength of 532 nm. Results indicate that the TiO2/ormosils based thin film presents a better OB-gain than that of the poly (methyl methacrylate) (PMMA) based thin film due to its more rigid network structure. Moreover, it is also noted that higher titanium content is helpful for enhancing the OB-gain of the as-prepared hybrid thin films.

  2. Elektrische apparaten van de ‘Nederlandsche Optiek- en Instrumentenfabriek Dr. C.E. Bleeker’

    Directory of Open Access Journals (Sweden)

    Kees Ruitenbeek

    2015-02-01

    Full Text Available Bleeker’s Electrical Instruments Mrs. Dr. C.E. Bleeker (1897–1985 led a company in optical and electrical instruments since 1932. While her optical instruments – including Prof. Frits Zernike’s Nobel Prize-winning phase contrast microscope – are well known, she also made a name in electrical devices. In addition to a series of highly accurate resistors – normal resistors, precision resistors and resistor banks – a range of electrical instruments were developed, such as Wheatstone bridges and compensators. In 1963, Dr Bleeker retired, but her firm continued until 1978, when nearly all activities ceased. Only the interests in Bleeker’s range of resistors continued. The current manufacturer still refers to ‘Bleeker’s principle’ in rela- tion to the quality of the resistors.

  3. GENESI-DR: Discovery, Access and on-Demand Processing in Federated Repositories

    Science.gov (United States)

    Cossu, Roberto; Pacini, Fabrizio; Parrini, Andrea; Santi, Eliana Li; Fusco, Luigi

    2010-05-01

    GENESI-DR (Ground European Network for Earth Science Interoperations - Digital Repositories) is a European Commission (EC)-funded project, kicked-off early 2008 lead by ESA; partners include Space Agencies (DLR, ASI, CNES), both space and no-space data providers such as ENEA (I), Infoterra (UK), K-SAT (N), NILU (N), JRC (EU) and industry as Elsag Datamat (I), CS (F) and TERRADUE (I). GENESI-DR intends to meet the challenge of facilitating "time to science" from different Earth Science disciplines in discovery, access and use (combining, integrating, processing, …) of historical and recent Earth-related data from space, airborne and in-situ sensors, which are archived in large distributed repositories. In fact, a common dedicated infrastructure such as the GENESI-DR one permits the Earth Science communities to derive objective information and to share knowledge in all environmental sensitive domains over a continuum of time and a variety of geographical scales so addressing urgent challenges such as Global Change. GENESI-DR federates data, information and knowledge for the management of our fragile planet in line with one of the major goals of the many international environmental programmes such as GMES, GEO/GEOSS. As of today, 12 different Digital Repositories hosting more than 60 heterogeneous dataset series are federated in GENESI-DR. Series include satellite data, in situ data, images acquired by airborne sensors, digital elevation models and model outputs. ESA has started providing access to: Category-1 data systematically available on Internet; level 3 data (e.g., GlobCover map, MERIS Global Vegetation Index); ASAR products available in ESA Virtual Archive and related to the Supersites initiatives. In all cases, existing data policies and security constraints are fully respected. GENESI-DR also gives access to Grid and Cloud computing resources allowing authorized users to run a number of different processing services on the available data. The GENESI-DR

  4. Studi Kelayakan Pengadaan Alat Picture Archiving and Communication System di RSUP Dr. Soeradji Tirtonegoro Klaten

    Directory of Open Access Journals (Sweden)

    Retno Dyah Parwitasari

    2017-01-01

    Full Text Available This study aimed to analyze the appropriateness of the technical aspects, the financial markets and the procurement plan PACS.Penelitian this is a case study located at the General Hospital Center (Dr Soeradji Tirtonegoro Klaten. This study found that investment decisions PACS instrument in terms of the technical aspects and the market has met. From the aspect of finance, investment appraisal results using PP is 2 years 239.4 days, less than a specified useful life, which is 5 years means that investment is worth it. The results of the NPV method is Rp.1.875.508.315,25, meaning that the investment is worth it. The results of the method IRR is 27%, greater than the specified rate of return of 6.5%, meaning that the investment is worth it. Thus we can conclude the investment project in the PACS instrument dr. Soeradji Tirtonegoro Klaten feasible.

  5. Dr.CHEN Ying-yi's Experience in Treating Premature Ovarian Failure

    Institute of Scientific and Technical Information of China (English)

    QIAN Hai-mo; FAN Xiao-yan; CHEN Ying-yi; WANG Xin-zhong

    2010-01-01

    @@ Dr.CHEN Ying-yi(陈颖异 1957-), female, chief physician, one of the forth-batch supervisors for the work of carrying on the academic experiences of the national veteran TCM experts.Dr.CHEN was once the student of the famous TCM professor HE Shao-shan, and has been engaged in TCM gynecology for more than 30 years, with more than30 essays published.She has taken charge of 5research subjects, of which 1 got the 3rd prize for the TCM scientific advance and creation of Zhejiang Province, 2 got the 3rd prize for Wenzhou municipal scientific advance, and 2 got the 2nd prize for Ruian municipal scientific advance.

  6. An Assessment of "What does photon energy tell us about cellphone safety" by Dr. William Bruno

    CERN Document Server

    Leikind, Bernard

    2011-01-01

    Dr. Bruno asserts the well-known fact that cell phones radiate microwaves in the classical regime. This, he says, means that the photon energy is not relevant to assessing safety. Citing optical tweezers as an example of biologically relevant non-thermal effects of electromagnetic radiation, Bruno concludes that all other reports of non-thermal effects from microwaves are likely valid. He seeks safety thresholds based upon requiring that cell phone energy density be less than k_BT. This proposal and related ideas produce thresholds many orders of magnitude below present values. While Dr. Bruno is correct that cell phone microwave radiation is generally in the classical regime, he uses peculiar estimates (number of photons per cubic wavelength) that overstate the circumstance by more than 20 factors of ten. He misunderstands the operation of optical tweezers and ignores their significant thermal effects. He credulously accepts poorly supported claims of non-existent non-thermal effects. He mistakenly believes ...

  7. Parenteral Admixture Compatibility in Neurosurgery Ward in Prof. Dr. Margono Soekarjo Regional Public Hospital

    Directory of Open Access Journals (Sweden)

    Laksmi Maharani

    2014-03-01

    Full Text Available Parenteral admixtures (intravenous admixtures have been done commonly in hospitals. However, it has a possibility of failures, like incompatibilities and changes in drug stabilities. The aim of this study was to determine the rate of drug incompatibilities in mixing parenteral preparations in neurosurgery ward in Prof. Dr. Margono Soekarjo Regional Public Hospital which undergo physical incompatibility observed in organoleptic. This study was a prospective descriptive research for one month period. Data were collected and analyzed descriptively. The results showed that from 667 parenteral admixtures in neurosurgery ward in Prof Dr Margono Soekarjo Hospital in February 2010, there were 0.45% potential incompatibility and 2.55% actual incompatibility happened. Actual incompatibility shown as crystal 0.17%, sediment 0.17%, and 2.04% was non-permanent haze in phenytoin and sodium chloride or ringer lactate admixtures.

  8. Canadian support for population stabilization. The Rome draft Plan of Action. Dr. Jean Augustine, MP (Canada).

    Science.gov (United States)

    1996-01-01

    Canada strongly believes in the central role to be played by the civil sector in the process leading to the World Food Summit. Dr. Augustine, Member of Parliament of Canada, described how the Canadian Government involved 350 national organizations over an eight-month period in the creation of the country's official position on food security. Canada has also negotiated with several other countries and international organizations on issues such as trade, human rights, the right to food, and follow-up to the Plan of Action. Dr. Augustine summarized Canada's 18 priorities for the World Food Summit. The priorities include human rights and good governance; poverty reduction; peace, security and conflict resolution; national responsibility for food security; national and global partnerships; nutrition and health; human resource development; gender equity; population stabilization; trade liberalization; agricultural adjustment to international markets; post-harvest marketing and food marketing; the role of the private sector; capacity building; environment and sustainable production; and research and technology transfer.

  9. Construction of source positioning system in RALS with using I.I.-DR image

    Energy Technology Data Exchange (ETDEWEB)

    Minamoto, Takahiro; Oda, Masahiko; Nakae, Yasuo [Hyogo Coll. of Medicine, Nishinomiya (Japan). Hospital; Kamikonya, Norihiko; Nakao, Norio [Hyogo Coll. of Medicine, Nishinomiya (Japan)

    2003-03-01

    In the Remote After Loading System (RALS), the source position is reconstructed as a 3 dimensional position by X-ray catheter points on bi-plane X-ray films. There are several reconstruction methods. However, the geometrical accuracy of the source coordinate position is important to evaluate dose distribution in any case. Many institutions adopted a C-arm X-ray fluoroscopic system with a rotational mechanism due to the simplicity of handling. However, the image intensifier (I.I.)-digital radiography (DR) image by the C-arm system has image distortion that results from mechanical accuracy and fluorescence plane of I.I., and films are used to confirm the source position in RALS. Therefore, the RALS positioning system that corrected I.I. DR image distortion was reconstructed. RALS positioning system kept reconstruction accuracy of the source coordinate position within 1 mm and this system also realized simplification of work and shortening in treatment time. (author)

  10. [The anatomy Lesson of Dr. Nicolaes Tulp: The beginning of a medical utopia].

    Science.gov (United States)

    Rosler, Roberto; Young, Pablo

    2011-04-01

    The Anatomy Lesson of Dr. Nicolaes Tulp was painted by Rembrandt Harmen-szoon van Rijn at the early age of 26 years. In the XVII century these paintings were very popular in the Netherlands, and in this country the cities flourished as cultural centers searching the anatomy knowledge. Nicolaes Tulp was one of the persons in the center of Amsterdam's scene during XVII century. In 1632 Tulp was 39 years old, and he was an anatomist and a surgeon. Rembrandt masterly shows an autopsy performed by Dr. Tulp. This picture is the description of the beginning of a medical intellectual utopia: the absolute visibility of the disease. Unfortunately this utopia is blind to the complete visibility of the psycho-socio-cultural dimensions of the ill.

  11. [Questions on the first operation with ethyl ether as anaesthetic by Dr. Peter Parker].

    Science.gov (United States)

    Chen, Q

    2017-01-28

    Ethyl ether was the first accepted effective general anaesthetic. It was introduced into China by an America missionary, Dr. Peter Parker. This was one of the historical events of medical communication between China and the West. In the records of the first operation with ether, however, Dr. Parker unusually omitted the patient's medical record number and the date of the operation, while those of other operations with ether anesthetics were all available. This was very unusual for a doctor like Peter Parker who always recorded every important case in detail in the hospital reports. It seems that he deliberately rather than carelessly omitted the information for some reasons. Based on the analysis of Parker's reports, a conclusion is made that the anesthetic effect of the case was actually ineffective. Furthermore, possible answers to this are outlined and question by discussion based on the situation that Parker faced in the late Qing era.

  12. A DR-WFOI fusion system for the real-time molecular imaging in vivo

    Institute of Scientific and Technical Information of China (English)

    Kun Bi; Xiaochun Xu; Lei Xi; Shaoqun Zeng; Qingming Luo

    2008-01-01

    Digital radiography (DR) and whole-body fluorescent optical imaging (WFOI) have been widely applied in the field of molecular imaging, with the advantages in tissues and functional imaging. The integration of them contributes to the development and discovery of medicine. We introduce an equipment, performance of which is better than that of another molecular imaging system manufactured by Kodak Corp. It can take real-time small animal imaging in vivo, with lower cost and shorter development cycle on the LabVIEW platform. At last, a paradigm experiment on a nude mouse with green fluorescent protein (GFP) transgenic tumor is given to present a real-time DR-WFOI fusion simultaneous image.

  13. Professor Dr. Chen Anmin voted in as the new president of Chinese German Society of Medicine

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ On June 24th 2006, Chinese German Society of Medicine (Chinesisch-Deutsche Gesellschaft für Medizin, CDGM) convened a representative assembly in Wuhan. Prof. Dr. Chen Anmin was elected as the new president of CDGM, who is also the director of Tongji Hospital, Tongji Medical College of Huazhong University of Science & Technology. In the mean time the Director Council and the Permanent Director's council were also selected. Mr.Dong Weiguo has been voted in as secretary-general.

  14. Dr. med. – obsolet? Eine Querschnittserhebung zur Wahrnehmung und Akzeptanz der medizinischen Doktorarbeit

    Directory of Open Access Journals (Sweden)

    Heun, Xenia

    2014-08-01

    Full Text Available [english] Purpose: To obtain the German Medical Degree “Dr.med.” candidates are required to write a scientific thesis which is usually accomplished during Medical school education. This extra work load for the students amongst a lack of standardization and an M.D. awarded upon graduation in other European and Anglo-Saxon countries leads repeatedly to criticism of the German system. However, a systematic survey on the perception and acceptance of the German doctoral thesis among those affected is overdue.Methods: Using an online questionnaire, medical students as well as licensed doctors were asked for the status of their medical degree, their motivation, personal benefit, time and effort, scientific output, its meaningfulness and alternatives concerning their thesis. Patients were asked, how important they value their general practitioner’s title “Dr. med.”. The resulting data were evaluated performing basic statistic analyses.Results and Conclusions: The title “Dr. med.“ does not seem to be obsolete, but there is room for improvement. The scientific output is good and only a mere 15.1% of the candidates do not publish their results at all. Moreover, while at an early stage motivation, appreciation and recognition of personal benefits from the medical degree are considered as independent aspects, they merge to a general view at later stages. The current practice is considered most meaningful by the ones who have already finished their thesis. However, there are discrepancies between the expected and the actual length as well as the type of the thesis indicating that mentoring and educational advertising need improvement. As for the patients, their educational level seems to correlate with the significance attributed to the title “Dr. med.” held by their physician.

  15. Faults Analysis and Diagnosis of DR J-460 Dish Centrifugal Separator's Helical Gear

    Institute of Scientific and Technical Information of China (English)

    MA Xiao-jian; GAN Xue-hui

    2004-01-01

    The main faults of dish centrifugal separator's helical gear are described in this paper. In order to diagnose the DR J-460 dish centrifugal separator correctly, the vibration is tested with a helical gear under both normal and abnormal conditions. After comparing several general methods of the gear's fault feature extraction, a new convenient and effective method is presented on the basis of analyzing the vibration spectrum under different rotary velocities.

  16. Dr. House: Patología dual en el médico

    Directory of Open Access Journals (Sweden)

    Mariano A. BELLINA

    2016-09-01

    Full Text Available Dr. House es una serie dramática estadounidense cuyo personaje central es el Dr. Gregory House, médi? co que dirige una unidad de diagnóstico (con otros tres doctores en el Hospital Universitario Princeton? Plainsboro, en Nueva Jersey. Dr. House utiliza un proceso lógico especial como base para llegar al diagnóstico. La Unidad que dirige el Dr. House trata pacientes que han sido evaluados previamente por otros doctores sin haber alcanzado un diagnóstico. Los diagnósticos oscilan desde algunos muy comunes a enfermedades raras. House no respeta las reglas y procedimientos comunes en la Medicina tradicional, tiene conflictos interpersonales graves (así como falta de empatía y no muestra interés por otras prácticas clínicas que no sean las suyas. Sufre un dolor crónico intenso en la pierna derecha por el que comienza a prescribirse Vicodin® (hidrocodona, al que acaba haciéndose dependiente. Nuestra hipótesis es que House es un caso típico de patología dual, PD (coexistencia de trastorno por uso de sustancias y otra enfermedad mental, en concreto: de dependencia de opiáceos y trastorno mixto de personalidad (comparte rasgos del trastorno de la personalidad antisocial y narcisista. La PD no es infrecuente en médicos dada la demora en pedir ayuda y la fácil accesibilidad a algunas sustancias.

  17. The Size of Narrow Line Region and [OIII] Luminosity Analyzed from SDSS DR7 Quasar Catalogue

    Indian Academy of Sciences (India)

    Zhi-Fu Chen; Y.-P. Qin; Z.-Y. Chen; L.-Z. Lü

    2011-03-01

    In this work, we constructed a sample of 4002 quasars from SDSS DR7 quasar catalogue to calculate the electron density and size of narrow line region. We find that the electron densities are ∼ 103/cm3, and the sizes are between 27 and 775 pc. We also find that, in the ionization cone, the sizes are tightly correlated with the luminosities of [OIII]5007.

  18. New supernova candidates from the SDSS-DR7 spectral survey

    Institute of Scientific and Technical Information of China (English)

    Liang-Ping Tu; A-Li Luo; Fu-Chao Wu; Chao Wu; Yong-Heng Zhao

    2009-01-01

    This letter presents 25 supernova candidates discovered from SDSS-DR7 by using our dedicated method, called Sample Decrease. Ten of them have been confirmed by other research groups, while the remaining 15, including 14 Type Ia and one Type Ⅱ, are first discovered based on Supernova Identification analysis. The results demonstrate that our method is reliable. The description of the method and some detailed spectral analysis procedures are also presented.

  19. Hiperbilirrubinemia neonatal en el hospital Dr. Teodoro Maldonado Carbo de la ciudad de Guayaquil, 2014

    OpenAIRE

    Salamea González, María José; Reinoso Mejía, Jenniffer Gabriela; Herrera Jaramillo, María Isabel

    2014-01-01

    Introducción: La hiperbilirrubinemia neonatal constituye una entidad clínica que se presenta con frecuencia en las unidades de Neonatología, por lo que es importante tener conocimiento sobre sus causas para prevenir secuelas. Objetivo: Determinar las principales causas de hiperbilirrubinemia neonatal en el Hospital Dr. Teodoro Maldonado Carbo de la ciudad de Guayaquil 2014. Materiales y Métodos: Se realizó un estudio cuantitativo, observacional, descriptivo, de corte transversal en ...

  20. The Role of Dr. Francis Willis in the Madness of George III.

    Science.gov (United States)

    Pearce, John M S

    2017-01-01

    In the well-known story of the illness of King George III, what is often overlooked is the part played by Dr. Francis Willis, an inconspicuous doctor who with great success ran an asylum in Lincolnshire. In November 1788, he was called to attend the King whose mania was becoming uncontrollable. Because of his interventions there was a slow but marked improvement. The King's recovery in 1789 increased Willis' reputation and expanded his practice. © 2017 S. Karger AG, Basel.

  1. The marriage of biology and technology. Professor Mogens Rysholt Poulsen interviewed by Dr Keith Farrington.

    Science.gov (United States)

    Poulsen, Mogens Rysholt

    2009-03-07

    Lab on a Chip is once again instigating a series of occasional interviews with those people running Departments/Institutions that we believe will be interesting to readers and provide a useful insight to other members of the community. In this first interview Dr Keith Farrington talks to Professor Mogens Rysholt Poulsen from DTU Nanotech because studies in this institute have recently expanded to include more biologically relevant areas of research in order to provide new biological insights.

  2. Infantile diarrhea in the Pediatric Ward of Dr. Pirngadi Hospital Medan.

    Science.gov (United States)

    Metrizal; Sinuhaji, A B; Sutanto, A H

    1991-01-01

    A retrospective study was done on infants with diarrhea who were hospitalized at the Pediatric ward of Dr. Pirngadi Hospital, Medan in a period of one year (January 1 to December 31, 1986). There were 3317 hospitalized patients and 1506 (45.40%) of them had diarrhea. Of these, 773 (51.32%) were in the age group of under 2 years. Thirty eight patients (4.91%) with infantile diarrhea died and prolonged diarrhea was found in 54 (6.98%) cases.

  3. Interview with Dr. Philip Stone, executive director of the Institute for Dark Tourism Research

    OpenAIRE

    BAILLARGEON, Taïka

    2016-01-01

    Dr. Philip Stone is the executive director of the Institute for Dark Tourism Research. Founded in 2012 and based at the University of Central Lancashire (UCLan), England, the iDTR largely contributes to scientific research on Dark Tourism while offering guidance to industry practitioners and collaborating with the media. In 2009, along with his colleague Richard Sharpley, Philip Stone published The Darker Side of Travel: The Theory and Practice of Dark Tourism. This book has become one of the...

  4. VizieR Online Data Catalog: SDSS damped Ly{alpha} survey: DR1 (Prochaska+, 2004)

    Science.gov (United States)

    Prochaska, J. X.; Herbert-Fort, S.

    2005-11-01

    We present the results from an automated search for damped Ly{alpha} (DLA) systems in the quasar spectra of Data Release 1 from the Sloan Digital Sky Survey (SDSS-DR1). At z~2.5, this homogeneous data set has greater statistical significance than the previous two decades of research. We derive a statistical sample of 71 DLA systems (>50 previously unpublished) at z>2.1 and measure HI column densities directly from the SDSS spectra. (1 data file).

  5. [Data mining for cataclysmic variables candidates in SDSS-DR8].

    Science.gov (United States)

    Jiang, Bin; Pan, Jing-Chang; Wang, Wei

    2013-02-01

    An automatic and efficient method for cataclysmic variables candidates is presented in this paper. The nonlinear locally linear embedding-LLE method is applied in the newly released SDSS-DR8 spectra. Spectra are dimension-reduced by LLE and classified by artificial neural network. The greatly reduced final candidates can be identified manually. 6 new CVs candidates were found in the experiment, and the compare between LLE with PCA shows the feasibility of nonlinear method in data mining in astronomical data.

  6. A study in dualism: The strange case of Dr. Jekyll and Mr. Hyde.

    Science.gov (United States)

    Singh, Shubh M; Chakrabarti, Subho

    2008-07-01

    R. L. Stevenson's novel, The Strange Case of Dr. Jekyll and Mr. Hyde is a prominent example of Victorian fiction. The names Jekyll and Hyde have become synonymous with multiple personality disorder. This article seeks to examine the novel from the view point of dualism as a system of philosophy and as a religious framework and also from the view point of Freud's structural theory of the mind.

  7. Assessment Of DR-55 As A Drop-In Replacement For R410A

    OpenAIRE

    Shen,Bo; Abdelaziz, Omar; Liudahl, Lane

    2016-01-01

    R410A has zero ozone depletion potential (ODP), and is the most commonly used refrigerant in vapor compression systems for space cooling and space heating applications. However, it has significant global warming potential with GWP higher than 2000. To mitigate the global warming effect, industry and research institutes are actively pursuing a replacement for R410A, which should have much lower GWP, similar or higher efficiency. Â DR-55 is a design-compatible refrigerant replacement for R410A...

  8. Assessment Of DR-55 As A Drop-In Replacement For R410A

    OpenAIRE

    Shen,Bo; Abdelaziz, Omar; Liudahl, Lane

    2016-01-01

    R410A has zero ozone depletion potential (ODP), and is the most commonly used refrigerant in vapor compression systems for space cooling and space heating applications. However, it has significant global warming potential with GWP higher than 2000. To mitigate the global warming effect, industry and research institutes are actively pursuing a replacement for R410A, which should have much lower GWP, similar or higher efficiency. Â DR-55 is a design-compatible refrigerant replacement for R410A...

  9. Datos biográficos del sr. dr. juan de dios carrasquilla l. 1833-1908

    OpenAIRE

    Revista de la, Facultad de Medicina

    2012-01-01

    Nació el Dr. Juan de Dios Carrasquilla Lema en la ciudad deBogotá, el día 19 de Marzo de 1833, en la casa marcada hoy con el número 210 de la carrera 8, antigua Calle de Florián.  Fueron sus padres D. Juan Manuel Carrasquilla y D. Candelaria Lema, naturales de Medellín.

  10. Gambaran Status Gizi Anak Talasemia β Mayor di RSUP Dr. M. Djamil Padang

    OpenAIRE

    2015-01-01

    Abstrak  Talasemia merupakan penyakit kronik yang membutuhkan transfusi setiap bulan, karena eritrosit lebih cepat lisis dibandingkan eritrosit normal. Komplikasi dan efek penyakit ini banyak, antara lain pertumbuhan, perkembangan, dan status gizinya. Penelitian ini bertujuan  mengetahui gambaran  status gizi anak talasemia β mayor Penelitian iniadalah penelitian deskriptif yang  dilakukan pada bulan Februari 2012 - Maret 2013 di RSUP Dr. M. Djamil Padang dengan sampel anak talasemia β mayor....

  11. Community control of health services. Dr. Martin Luther King, Jr. Health Center's community management system.

    Science.gov (United States)

    Tichy, N M; Taylor, J I

    1976-01-01

    This article presents the case of Dr. Martin Luther King Jr. Health Center's unique community management system in which neighborhood workers have been developed to assume managerial responsibilities and are directing the Center. The Martin Luther King Center experience is instructive because the Center was able to achieve significant community control by focusing primarily on the internal dimension of control, namely, management, without experiencing destructive conflicts and the deterioration of health services.

  12. Leading Healthcare Change Across the Care Continuum: An Interview With Dr Kenneth Rempher.

    Science.gov (United States)

    Murphy, Lyn Stankiewicz; Joseph, M Lindell

    2016-01-01

    Kenneth Rempher, PhD, MBA, CENP, RN, is the chief nursing officer for the University of Iowa (UI) Hospitals and Clinics. In his 20-year career, he has distinguished himself as a visionary healthcare leader. Colleagues describe Dr Rempher as a strong, transformational leader, guiding the UI enterprise through a time of uncertainty and change. This interview by the CGEAN provides insight to his leadership style, successes, and ideas on the future of care delivery.

  13. A Novel Prediction Algorithm of DR Position Error Based on Bayesian Regularization Back-propagation Neural Network

    Directory of Open Access Journals (Sweden)

    Li Honglian

    2013-07-01

    Full Text Available It is difficult to accurately reckon vehicle position for vehicle navigation system (VNS during GPS outages, a novel prediction algorithm of dead reckon (DR position error is put forward, which based on Bayesian regularization back-propagation (BRBP neural network. DR, GPS position data are first de-noised and compared at different stationary wavelet transformation (SWT decomposition level, and DR position error data are acquired after the SWT coefficients differences are reconstructed. A neural network to mimic position error property is trained with back-propagation algorithm, and the algorithm is improved for improving its generalization by Bayesian regularization theory. During GPS outages, the established prediction algorithm predictes DR position errors, and provides precise position for VNS through DR position error data updating DR position data. The simulation results show the positioning precision of the BRBP algorithm is best among the presented prediction algorithms such as simple DR and adaptive linear network, and a precise mathematical model of navigation sensors isn’t established.

  14. HLA-DR allele frequencies in Mexican mestizos with autoimmune liver diseases including overlap syndromes.

    Science.gov (United States)

    Zepeda-Gomez, Sergio; Montaño-Loza, Aldo; Zapata-Colindres, Juan Carlos; Paz, Francisco; Olivera-Martinez, Marco; López-Reyes, Alberto; Granados, Julio; Vargas-Alarcón, Gilberto

    2009-01-01

    Autoimmune liver diseases are sometimes difficult to differentiate from hepatic overlap syndromes (OS). The objective of this study was to use polymorphic genetic markers to better distinguish clinical heterogeneity in autoimmune liver disease. Since autoimmunity is the result of autoantibody production we studied HLA-DR alleles in 20 patients with autoimmune hepatitis (AIH), 16 with primary biliary cirrhosis (PBC), 10 with OS, and in 99 ethnically matched healthy individuals. Patients with OS had significantly higher alkaline phosphatase and total bilirubin levels than patients with AIH. OS patients had a higher prevalence of positive antinuclear antibodies and a higher AIH score than patients with PBC. Patients with OS also had higher total immunoglobulin levels (IgG isotype) as compared to patients with PBC. We found in PBC patients a higher gene frequency of HLA-DR4 and DR1 as compared to healthy controls (p = 0.03, OR = 2.2 and p = 0.004, OR = 4.3, respectively) and to OS patients (p = 0.01, OR = 6.8, and p = 0.004, OR = 10.0, respectively). On the other hand, the gene frequency of HLADR5 was significantly decreased in the total group of patients as compared to healthy controls suggesting a protective role of this allele for developing autoimmune liver disease.

  15. DR Tau: Temporal variability of the brightness distribution in the potential planet-forming region

    CERN Document Server

    Brunngräber, Robert; Ratzka, Thorsten; Ober, Florian

    2016-01-01

    We investigate the variability of the brightness distribution and the changing density structure of the protoplanetary disk around DR Tau, a classical T Tauri star. DR Tau is known for its peculiar variations from the ultraviolet (UV) to the mid-infrared (MIR). Our goal is to constrain the temporal variation of the disk structure based on photometric and MIR interferometric data. We observed DR Tau with the MID-infrared Interferometric instrument (MIDI) at the Very Large Telescope Interferometer (VLTI) at three epochs separated by about nine years, two months, respectively. We fit the spectral energy distribution and the MIR visibilities with radiative transfer simulations. We are able to reproduce the spectral energy distribution as well as the MIR visibility for one of the three epochs (third epoch) with a basic disk model. We were able to reproduce the very different visibility curve obtained nine years earlier with a very similar baseline (first epoch), using the same disk model with a smaller scale heigh...

  16. Indications of Tonsillectomy and Adenoidectomy in Dr. Hasan Sadikin General Hospital Bandung

    Directory of Open Access Journals (Sweden)

    Dini Atiyah

    2015-03-01

    Full Text Available Background: Tonsillectomy is the intervention to take out the palatine tonsils either whole or sub capsular, while adenoidectomy is the intervention of extraction of the adenoid gland which is commonly done with curettage method. Both interventions are done to eliminate repeated infections and also obstructions due to inflammation and hypertrophy of the tonsils and adenoids. This study was conducted to examine the indications of tonsillectomy and adenoidectomy in the Departement of Otorhinolaryngology and Head Neck Surgery Dr. Hasan Sadikin General Hospital Bandung in the period of January 2009–December 2011. Methods: A cross-sectional descriptive study was conducted in October–November of 2012 using 207 medical records of patients who had tonsillectomy and adenoidectomy executed in the Department of Otorhinolaryngology and Head Neck Surgery Dr. Hasan Sadikin General Hospital, Bandung in the period of January 2009–December 2011. Data collected were age, gender, main complaint, tonsil size, history of repeated infections, history of snoring as well as of Obstructive Sleep Apnea Syndrome (OSAS. The indication for tonsillectomy and adenoidectomy such as infection, obstruction and neoplasia was selected. Results: The indications of tonsillectomy and adenoidectomy were infection at 106 (51.2% patients, obstruction at 100 (48.3% patients, and neoplasia at 1 (0.05% patient. Conclusions: The most numerous indications for tonsillectomy and tonsilloadenoidectomy in the Department of Otorhinolaryngology and Head Neck Surgery Dr. Hasan Sadikin General Hospital were infection.

  17. Role of HLA-DR Alleles to Increase Genetic Susceptibility to Onychomycosis in Nail Psoriasis

    Science.gov (United States)

    Carrillo-Meléndrez, Hilda; Ortega-Hernández, Esteban; Granados, Julio; Arroyo, Sara; Barquera, Rodrigo; Arenas, Roberto

    2016-01-01

    Background Patients with nail psoriasis have an increased risk of onychomycosis. Previous studies suggest it may be due to structural changes of the nails. However, a genetic predisposition seems to be also at play. Objective To determine a genetic susceptibility for onychomycosis in nails with changes of psoriasis. Methods This is a prospective case-control study of patients with suggestive changes of nail psoriasis with onychomycosis (cases) and without onychomycosis (controls) confirmed by mycological tests. HLA typing was performed in all of them by sequence-specific primers. Results Twenty-five patients and 20 controls with a mean age of 50 years (range 37-72 years) were studied. HLA-DRB1*08 was found in 12 cases (48%) and only 3 controls (15%) [p < 0.033, odds ratio (OR) = 3.8, 95% confidence interval (CI): 0.9-19]. HLA-DR1 was found in 9 cases (36%) and only 1 control (5%) (p < 0.023, OR = 8.5, 95% CI: 1-188). Conclusion HLA-DR*08 and HLA-DR*01 probably increase the susceptibility to fungal infection in psoriasis-affected nails, but larger studies are required to confirm this observation. PMID:27843918

  18. Association of Alport's syndrome with HLA-DR2 antigen in a group of unrelated patients

    Directory of Open Access Journals (Sweden)

    E.A. Donadi

    1998-04-01

    Full Text Available A few family studies have evaluated HLA antigens in Alport's syndrome; however, there are no large population studies. In the present report, we studied 40 unrelated white patients with Alport's syndrome seen at the Unit of Renal Transplantation, Faculty of Medicine of Ribeirão Preto, São Paulo, Brazil. HLA-A, -B, -DR and -DQ antigens were typed using a complement-dependent microlymphocytotoxicity assay. A control white population (N = 403 from the same geographical area was also typed for HLA antigens. Although the frequencies of HLA-A and -B antigens of patients were not statistically different from controls, the frequency of HLA-DR2 antigen observed in patients (65% was significantly increased in relation to controls (26%; P<0.001. The relative risk and etiologic fraction for HLA-DR2 antigen were 5.2 and 0.525, respectively. Although few immunological abnormalities have been shown in Alport's syndrome, in this report we emphasize the association of HLA molecules and Alport's syndrome. Besides the well-known inherited molecular defects encoded by type IV collagen genes in Alport's syndrome, the major histocompatibility alleles may be in linkage disequilibrium with these defective collagen genes

  19. The Zeeman Effect in the 44 GHz Class I Methanol Maser Line toward DR21(OH)

    Science.gov (United States)

    Momjian, E.; Sarma, A. P.

    2017-01-01

    We report detection of the Zeeman effect in the 44 GHz Class I methanol maser line, toward the star-forming region DR21(OH). In a 219 Jy beam‑1 maser centered at an LSR velocity of 0.83 km s‑1, we find a 20-σ detection of zBlos = 53.5 ± 2.7 Hz. If 44 GHz methanol masers are excited at n ∼ 107–8 cm‑3, then the B versus n1/2 relation would imply, from comparison with Zeeman effect detections in the CN(1 ‑ 0) line toward DR21(OH), that magnetic fields traced by 44 GHz methanol masers in DR21(OH) should be ∼10 mG. Combined with our detected zBlos = 53.5 Hz, this would imply that the value of the 44 GHz methanol Zeeman splitting factor z is ∼5 Hz mG‑1. Such small values of z would not be a surprise, as the methanol molecule is non-paramagnetic, like H2O. Empirical attempts to determine z, as demonstrated, are important because there currently are no laboratory measurements or theoretically calculated values of z for the 44 GHz CH3OH transition. Data from observations of a larger number of sources are needed to make such empirical determinations robust.

  20. The life and viper of Dr Patrick Russell MD FRS (1727-1805): physician and naturalist.

    Science.gov (United States)

    Hawgood, B J

    1994-11-01

    It is nearly two hundred years since the publication in 1796 of An Account of Indian Serpents collected on the Coast of Coromandel by Patrick Russell. Within the folio is a drawing and description of the venomous snake called Katuka Rekula Poda in the local Telugu language, whose venom was shown experimentally by Dr Russell to be nearly as lethal as that of Cobra de Capello. The snake is now known as Vipera russelli or Russell's viper. Dr Russell was representative of the naturalistic tendency of British medicine in the late 18th century. He was a keen observer and skilled doctor in clinical practice, particularly in Aleppo, Syria, during an outbreak of the plague, and indefatigable in his study of plant and animal life both in Aleppo and later in the Madras Province of India. As a physician as well as Naturalist to the East India Company in the Carnatic he was concerned with the problem of snakebite. His first aim was to find a means whereby the non-specialist could distinguish between poisonous and harmless snakes and so combat the terrible notion that all bites were mortal. His writing, encompassing social and natural histories and climaxed by a study of snakes, has left a rich legacy. Dr Patrick Russell was a man of the highest integrity and ability, a physician and naturalist par excellence.

  1. The Zeeman Effect in the 44 GHz Class I Methanol Maser Line toward DR21(OH)

    CERN Document Server

    Momjian, E

    2016-01-01

    We report the detection of the Zeeman effect in the 44 GHz Class I methanol maser line toward the star forming region DR21(OH). In a 219 Jy/beam maser centered at an LSR velocity of 0.83 km s$^{-1}$, we find a 20-$\\sigma$ detection of $zB_{\\text{los}} = 53.5 \\pm 2.7$ Hz. If 44 GHz methanol masers are excited at $n \\sim 10^{7-8}$ cm$^{-3}$, then the $B~vs.~n^{1/2}$ relation would imply from comparison with Zeeman effect detections in the CN($1-0$) line toward DR21(OH) that magnetic fields traced by 44 GHz methanol masers in DR21(OH) should be $\\sim$10 mG. Together with our detected $zB_{\\text{los}} = 53.5$ Hz, this would imply that the value of the 44 GHz methanol Zeeman splitting factor $z$ is $\\sim$5 Hz mG$^{-1}$. Such small values of $z$ would not be a surprise, as the methanol molecule is non paramagnetic, like H$_2$O. Empirical attempts to determine $z$, as demonstrated, are important because currently there are no laboratory measurements or theoretically calculated values of $z$ for the 44 GHz methanol t...

  2. Treatment of Infantile Night Crying by Dr. SHAN's Infantile Tuina Therapy

    Institute of Scientific and Technical Information of China (English)

    ZHENG Lan-feng

    2004-01-01

    In order to observe the clinical effect of Tuina therapy for infantile night crying, 20 cases of infantile night crying were treated by Dr. SHAN's infantile Tuina therapy upon pattern identification.In 20 cases, the results showed cure in 12 cases, improvement in 6 cases, failure in 2 cases and the total effective rate in 90.0%. Dr. SHAN's infantile Tuina therapy was created by late Dr. SHAN Ji-ping and is remarkably effective in the therapeutic effects and easy to be accepted by sick children.%观察以推拿疗法治疗小儿夜啼的临床效果.对20例小儿夜啼采用单氏小儿推拿法辨证治疗.20例患者,治愈12例,好转6例,无效2例,总有效率90.0%.单氏小儿推拿法由已故单吉平医师所创,疗效显著,易受患儿所接受.

  3. The Gaia DR1 Mass-Radius Relation for White Dwarfs

    CERN Document Server

    Tremblay, P -E; Raddi, R; Jordan, S; Besson, C; Gaensicke, B T; Parsons, S G; Koester, D; Marsh, T; Bohlin, R; Kalirai, J

    2016-01-01

    The Gaia Data Release 1 (DR1) sample of white dwarf parallaxes is presented, including 6 directly observed degenerates and 46 white dwarfs in wide binaries. This data set is combined with spectroscopic atmospheric parameters to study the white dwarf mass-radius relationship (MRR). Gaia parallaxes and G magnitudes are used to derive model atmosphere dependent white dwarf radii, which can then be compared to the predictions of a theoretical MRR. We find a good agreement between Gaia DR1 parallaxes, published effective temperatures (Teff) and surface gravities (log g), and theoretical MRRs. As it was the case for Hipparcos, the precision of the data does not allow for the characterisation of hydrogen envelope masses. The uncertainties on the spectroscopic atmospheric parameters are found to dominate the error budget and current error estimates for well-known and bright white dwarfs may be slightly optimistic. With the much larger Gaia DR2 white dwarf sample it will be possible to explore the MRR over a much wide...

  4. The Gaia DR1 mass-radius relation for white dwarfs

    Science.gov (United States)

    Tremblay, P.-E.; Gentile-Fusillo, N.; Raddi, R.; Jordan, S.; Besson, C.; Gänsicke, B. T.; Parsons, S. G.; Koester, D.; Marsh, T.; Bohlin, R.; Kalirai, J.; Deustua, S.

    2017-03-01

    The Gaia Data Release 1 (DR1) sample of white dwarf parallaxes is presented, including six directly observed degenerates and 46 white dwarfs in wide binaries. This data set is combined with spectroscopic atmospheric parameters to study the white dwarf mass-radius relationship (MRR). Gaia parallaxes and G magnitudes are used to derive model atmosphere-dependent white dwarf radii, which can then be compared to the predictions of a theoretical MRR. We find a good agreement between Gaia DR1 parallaxes, published effective temperatures (Teff) and surface gravities (log g), and theoretical MRRs. As it was the case for Hipparcos, the precision of the data does not allow for the characterization of hydrogen envelope masses. The uncertainties on the spectroscopic atmospheric parameters are found to dominate the error budget and current error estimates for well-known and bright white dwarfs may be slightly optimistic. With the much larger Gaia DR2 white dwarf sample, it will be possible to explore the MRR over a much wider range of mass, Teff, and spectral types.

  5. Morusin Induces TRAIL Sensitization by Regulating EGFR and DR5 in Human Glioblastoma Cells.

    Science.gov (United States)

    Park, Dain; Ha, In Jin; Park, Sang-Yoon; Choi, Minji; Lim, Sung-Lyul; Kim, Sung-Hoon; Lee, Jun-Hee; Ahn, Kwang Seok; Yun, Miyong; Lee, Seok-Geun

    2016-02-26

    Glioblastoma is one of the most malignant primary tumors, and the prognosis for glioblastoma patients remains poor. Tumor-necrosis-factor-related apoptosis-inducing ligand (TRAIL) is considered a promising anticancer agent due to its remarkable ability to selectively kill tumor cells. However, since many cancers are resistant to TRAIL, strategies to overcome resistance are required for the successful use of TRAIL in the clinic. In the present study, the potential of morusin as a TRAIL sensitizer in human glioblastoma cells was evaluated. Treatment with TRAIL or morusin alone showed weak cytotoxicity in human glioblastoma cells. However, combination treatment of TRAIL with morusin synergistically decreased cell viability and increased apoptosis compared with single treatment. Morusin induced expression of death receptor 5 (DR5), but not DR4 or decoy receptors (DcR1 and DcR2). Furthermore, morusin significantly decreased anti-apoptotic molecules survivin and XIAP. In addition, morusin reduced expression of EGFR and PDFGR as well as phosphorylation of STAT3, possibly mediating down-regulation of survivin and XIAP. Together these results suggest that morusin enhances TRAIL sensitivity in human glioblastoma cells through regulating expression of DR5 and EGFR. Therefore, the combination treatment of TRAIL and morusin may be a new therapeutic strategy for malignant glioma patients.

  6. Acceptance of Medical Resume Completion at Dr. Radjiman Wediodiningrat Lawang Psychiatric Hospital

    Directory of Open Access Journals (Sweden)

    Silvia Shinta Devi

    2017-02-01

    Sistem kesehatan di Indonesia mengalami perubahan besar dengan diberlakukannya program Asuransi Kesehatan Nasional. Resume medis memiliki peran penting dalam klaim asuransi kesehatan, sehingga resume medis yang terlambat dan tidak lengkap akan mengganggu proses klaim asuransi. Penelitian ini bertujuan untuk mengetahui pengaruh persepsi kemudahan penggunaan, persepsi manfaat, dan sikap pada penerimaan dokter dalam menyelesaikan resume medis. di Dr Radjiman Wedyodiningrat Psychiatric Hospital Lawang berdasarkan Technology Acceptance Model. Technology Acceptance Model digunakan sebagai model dalam penelitian ini karena resume medis merupakan salah satu bentuk teknologi informasi yang masih dilakukan secara manual. Pengumpulan data untuk penelitian ini dilakukan pada bulan Maret 2016 dengan menggunakan kuesioner yang diberikan kepada 32 dokter di Rumah Sakit Jiwa Dr Radjiman Wediodiningrat Lawang. Skala Likert lima tingkat digunakan untuk mengukur setiap item variabel. Data dianalisis dengan menggunakan Partial Least Square. Hasil penelitian menunjukan bahwa secara umum, acceptance dokter di RSJ Dr. Radjiman Wediodiningrat Lawang terhadap pengisian resume medis masuk dalam kategori ringgi dan memiliki perceived usefulness and attitude yang dalam kategori baik, sedangkan perceived ease of use dalam kategori sedang.

  7. Prof. John Wood, Chief Executive Designate, Dr Gordon Walker, Directorate, Chief Executive, Prof. Ken J. Peach, Head of the Particle Physics Department, CLRC Rutherford Appleton Laboratory, United Kingdom

    CERN Document Server

    Patrice Loïez

    2001-01-01

    L. to. r.: Dr. Ian Wilson, CLIC Deputy Study Leader, Prof. Ken J. Peach, Head of the Particle Physics Department, Prof. John Wood, Chief Executive Designate, Dr. Gordon Walker, Directorate, Chief Executive

  8. HLA-DR polymorphism in a senegalese mandenka population: DNA oligotyping and population genetics of DRB1 specificities

    Energy Technology Data Exchange (ETDEWEB)

    Tiercy, J.M.; Shi-Isaac, X.; Jeannet, M.; Sanchez-Mazas, A.; Langaney, A.; Mach, B.; Excoffier, L.

    1992-09-01

    HLA class II loci are useful markers in human population genetics, because they are extremely variable and because new molecular techniques allow large-scale analysis of DNA allele frequencies. Direct DNA typing by hybridization with sequence-specific oligonucleotide probes (HLA oligotyping) after enzymatic in vitro PCR amplification detects HLA allelic polymorphisms for all class II loci. A detailed HLA-DR oligotyping analysis of 191 individuals from a geographically, culturally, and genetically well-defined western African population, the Mandenkalu, reveals a high degree of polymorphism, with at least 24 alleles and a heterozygosity level of .884 for the DRB1 locus. The allele DRB1[sup *]1304, defined by DNA sequencing of the DRB1 first-domain exon, is the most frequent allele (27.1%). It accounts for an unusually high DR13 frequency, which is nevertheless within the neutral frequency range. The next most frequency specificities are DR11, DR3, and DR8. Among DRB3-encoded alleles, DR52B (DRB3[sup *]02) represents as much as 80.7% of all DR52 halotypes. A survey of HLA-DR specificities in populations from different continents shows a significant positive correlation between genetic and geographic differentiation patterns. A homozygosity test for selective neutrality of DR specificities is not significant for the mandenka population but is rejected for 20 of 24 populations. Observed high heterozygosity levels in tested populations are compatible with an overdominant model with a small selective advantage for heterozygotes. 91 refs., 5 figs., 5 tabs.

  9. Methylprednisolone treatment increases the proportion of the highly suppressive HLA-DR(+)-Treg-cells in transplanted patients.

    Science.gov (United States)

    Seissler, Nicole; Schmitt, Edgar; Hug, Friederike; Sommerer, Claudia; Zeier, Martin; Schaier, Matthias; Steinborn, Andrea

    2012-12-01

    Methylprednisolone is widely used to improve immune suppression in transplanted patients threatened by acute rejection. Recently, we showed that the suppressive activity of a Treg cell population depends decisively on their percentage of highly suppressive HLA-DR(high+)-Treg cells, which are strongly reduced in rejecting transplant patients. In order to examine whether the composition of the total CD4(+)CD127(low+/-)FoxP3(+)-Treg cell pool with different Treg-subsets (DR(high+)CD45RA(-)-Tregs, DR(low+)CD45RA(-)-Tregs, DR(-)CD45RA(-)-Tregs, DR(-)CD45RA(+)-Tregs) is affected by methylprednisolone bolus therapy we compared the percentages of these four different Treg cell subsets in transplant patients with biopsy proven rejection before and after steroid bolus therapy (n=23). In patients treated with steroid bolus therapy, the percentage of the naïve DR(-)CD45RA(+)-Tregs was significantly decreased, whereas the percentage of the DR(+)CD45RA(-)-Tregs was significantly increased. By that, the strongest increase was detected for the most suppressive DR(high+)CD45RA(-)-Tregs. However, these effects were only temporarily and closely associated to the duration of the bolus therapy. Our results suggest that besides various anti-inflammatory effects on cells of the adaptive and innate immune system, methylprednisolone also has the capacity to enhance the suppressive activity of the total Treg cell pool by increasing its percentage of highly differentiated and highly suppressive DR(high+)CD45RA(-)-Tregs. Copyright © 2012 Elsevier B.V. All rights reserved.

  10. Purification and characterization of DR_2577 (SlpA) a major S-layer protein from Deinococcus radiodurans.

    Science.gov (United States)

    Farci, Domenica; Bowler, Matthew W; Esposito, Francesca; McSweeney, Sean; Tramontano, Enzo; Piano, Dario

    2015-01-01

    The protein DR_2577 is a major Surface layer component of the radio-resistant bacterium Deinococcus radiodurans. In the present study DR_2577 has been purified and its oligomeric profile characterized by means of size exclusion chromatography and gel electrophoresis. DR_2577 was found to be organized into three hierarchical orders characterized by monomers, stable dimers formed by the occurrence of disulfide bonds, and hexamers resulting from a combination of dimers. The structural implications of these findings are discussed providing new elements for a more integrated model of this S-layer.

  11. Dr. Andras Siegler, President of the Hungarian CERN Committee, Ministry of Education, Research and Development Division, Budapest, Hungary

    CERN Document Server

    Maximilien Brice

    2002-01-01

    Photo 01: Dr András Siegler, President of the Hungarian CERN Committee, Ministry of Education, Research and Development Division (right) visiting the ALICE data acquisition laboratory with Ervin Denes. Photo 02: Ervin Denes in the ALICE DAQ (data acquisition) laboratory on the occasion of the visit of Dr András Siegler, President of the Hungarian CERN Committee, Ministry of Education, Research and Development Division. Photo 03: Detector Data Link and data generator used for data acquisition system of the ALICE experiment photographed on the occasion of the visit of Dr. András Siegler, President of the Hungarian CERN Committee, Ministry of Education, Research and Development Division.

  12. Purification and characterization of DR_2577 (SlpA) a major S-layer protein from Deinococcus radiodurans

    Science.gov (United States)

    Farci, Domenica; Bowler, Matthew W.; Esposito, Francesca; McSweeney, Sean; Tramontano, Enzo; Piano, Dario

    2015-01-01

    The protein DR_2577 is a major Surface layer component of the radio-resistant bacterium Deinococcus radiodurans. In the present study DR_2577 has been purified and its oligomeric profile characterized by means of size exclusion chromatography and gel electrophoresis. DR_2577 was found to be organized into three hierarchical orders characterized by monomers, stable dimers formed by the occurrence of disulfide bonds, and hexamers resulting from a combination of dimers. The structural implications of these findings are discussed providing new elements for a more integrated model of this S-layer. PMID:26074883

  13. Dr Julia King CBE FREng, Chief Executive Designate, Institute of Physics (United Kingdom), visiting the NA48 experiment.

    CERN Document Server

    Patrice Loïez

    2002-01-01

    Photo 02: Visiting the NA48 experiment, Dr Julia King, Chief Executive Designate, Institute of Physics (Britain and Ireland) (right) with A. Ceccucci and K. Peach. Photo 05: Visiting the NA48 experiment, Dr Julia King, Chief Executive Designate, Institute of Physics (Britain and Ireland) (centre) with A. Ceccucci and C. Lazzeroni. Photo 08: Visiting the NA48 experiment, Dr Julia King, Chief Executive Designate, Institute of Physics (Britain and Ireland) (second from left) with (left to right) R. Barlow, J. Wood, N. McCubbin, K. Peach, A. Ceccucci, C. Lazzeroni, M. Patel and D. Munday.

  14. 月球车DR/CNS组合导航研究%A Study on DR/CNS Integrated Navigation for Lunar Robot

    Institute of Scientific and Technical Information of China (English)

    封红鹏; 居鹤华; 刘洋波; 孙飞

    2011-01-01

    This paper presents a lunar DR/CNS integrated navigation scheme against the lunar's characteristics of weak magnetic, high dust, slow self-spin, off-satellite and lunar-rovers ultra-low speed which lead the failure of most conventional navigation methods. The proposed method uses dead- reckoning to calculate the definite displacement and uses solar compass to determine the heading angle. This paper makes a research from the source of system errors and non- system errors with dead- reckoning while establishes a model for the odometer error. A self-developed solar compass has been introduced on the base of comprehensive consideration with the specificity of the moon's surface environment. Experimental results show the feasibility and effectiveness of the integrated navigation.%针对月面环境弱地磁、高粉尘、慢自旋、无卫星及月球车超低速,大多传统导航方法失效的问题,设计了以航位推算确定位移、太阳罗盘确定航向角的月球车DR/CNS组合导航方案;分别从航位推算的系统误差和非系统误差来源研究,并建立了里程计误差模型;在充分考虑到月面环境特殊性的基础上,自主研制了太阳罗盘;实验证明了该组合导航方案的可行性和有效性.

  15. Hubungan Tekanan Darah Ibu Hamil Aterm Dengan Berat Badan Lahir di RSUP Dr. M. Djamil Padang

    Directory of Open Access Journals (Sweden)

    Feby Andammori

    2013-05-01

    Full Text Available AbstrakTinggi rendahnya tekanan darah sistolik dan diastolik dalam kehamilan mempunyai pengaruh terhadap berat badan lahir. Penelitian ini bertujuan untuk mengidentifikasi hubungan tekanan darah ibu hamil aterm dengan berat badan lahir di RSUP dr M. Djamil Padang. Metode penelitian : Penelitian yang dilakukan merupakan survei analitik dengan menggunakan studi komparatif dengan design penelitian Cross Sectional Study. Penelitian menggunakan data sekunder yang diambil dari sub bagian Rekam Medik (Medical Record RSUP dr. M. Djamil Padang bulan Januari 2010 – Desember 2012 dengan jumlah sampel 34 orang ibu hamil yang tidak hipertensi dan 34 orang ibu hamil yang mengalami hipertensi dalam kehamilannya. Hasil penelitian : Ditemukan rata-rata berat badan lahir bayi yang dilahirkan oleh kelompok ibu yang tidak mengalami hipertensi pada kehamilannya adalah 3.408 (SD 307 gram dan rata-rata berat badan lahir bayi yang dilahirkan oleh kelompok ibu yang mengalami hipertensi pada kehamilannya adalah 2.799 (SD 413 gram. Dari hasil uji analisis Independent Sample T-test diperoleh hasil ditemukan adanya hubungan tekanan darah ibu hamil dengan berat badan lahir di RSUP dr. M. Djamil Padang p = 0,00 (p < 0,05. Kesimpulan : Pemeriksaan kehamilan secara teratur penting untuk mengantisipasi adanya peningkatan tekanan darah ibu hamil yang dapat berpengaruh terhadap berat bayi lahir.Kata kunci: tekanan darah, berat badan lahir, ibu hamilAbstractHigh and low level of systolic and diastolic blood pressure in pregnancy has impact to birth weight. This research is purposed to identify the relation between aterm pregnant blood pressure and birth weight.Methods : This research is analytical survey which used comparative study with Cross Sectional Study design. This research used secondary data taken from Medical Record in RSUP dr. M. Djamil Padang since Januari 2010 until December 2012 with number of samples are 34 pregnant women who have not hypertension and 34 pregnant

  16. Expression of intercellular adhesion molecule-1and HLA-DR antigens in uveitis

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    目的:研究细胞间粘附分子-1(intellular adhesion molecule-1,ICAM-1)和人体组织相关抗原(human leudocyte antigen,HLA-DR)在萄萄膜炎免疫反应中的作用.方法:应用免疫组织化学染色检查20只正常眼和54例葡萄糖膜炎眼球摘除眼(其中外源性33例和内源性21例)的脉络膜和视网膜组织中ICAM-1和HLA-DR的表达.结果:正常眼的脉络膜和视网膜组织没有ICAM-1的阳性染色,没有或较少有HLA-DR的表达,葡萄膜炎眼中二者有增高表达(P<0.01),而外源性和内源性葡萄膜炎眼组间表达统计学上无显著差异(P>0.05).结论:ICAM-1、HLA-DR分子能够介导白细胞和炎症部位组织细胞的识别和粘附,二者的共同表达说明它们在葡萄糖膜炎脉络膜视网膜组织的免疫性损伤中具有重要意义.%Objective :To study the effects of intercellular adhesion molecule-1 (ICAM-1) and human leukocyte antigen (HAL-DR) on the immunopathologic process of uveitis. Methods:Imn- munohistochemical techniques were applied to detect their expression in eyes of both the health (20 cases from eye bank) and patients with uveitis (54 cases with 54 eyes which included 33 ex- ogenous uveitis and 21 endogenous one). Results:Both the two ant igens were detectable in the choroidal and retinal tissues in eyes of uveitis while all the normal eyes showed negative expres- sion of ICAM-1 and negative or little expression of HLA-DR (P<0. 01). However,there was no statistically significant difference between exogenous and endogenous types (P>0. 05). Conclu- sion: Both ICAM-1 and HLA-DR may be responsible for cell recognition and binding in the in- flarnmatory tissues. The co-expression of ICAM-1 and HAL-DR showed that these two factors might play an important role in the immunologic damage of the choroid and retina in uveitis.

  17. Interview with one of the 2004 Nobel Laureates in Physics, Dr. David J. Gross, January 26, 2005

    CERN Multimedia

    CERN Video Productions

    2005-01-01

    Dr. David Gross, (Professor of Theoretical Physics, Director of the Kavli Institute For Theoretical Physics, University of California, Santa Barbara), at CERN for a talk, answered the questions of Paola Catapano

  18. Capacity-Building Programs Under the Dominican Republic-Central America-United States Free Trade Agreement (CAFTA-DR)

    Science.gov (United States)

    The United States signed the Dominican Republic-Central America-United States Free Trade Agreement (CAFTA-DR) in August 2004 with five Central American countries (Costa Rica, El Salvador, Guatemala, Honduras, and Nicaragua) and the Dominican Republic.

  19. Typing for HLA-D/DR associated DP-antigens with the primed lymphocyte typing (PLT) technique

    DEFF Research Database (Denmark)

    Morling, N; Jakobsen, B K; Platz, P

    1980-01-01

    A total of 74 healthy unrelated random individuals and 36 patients with juvenile rheumatoid arthritis (JRA) were typed for HLA-D antigens with the homozygous typing cell technique and typed for HLA-D/DR associated DP-antigens with the primed lymphocyte typing (PLT) technique. All patients and some...... of the controls were also HLA-DR typed with a limited battery of anti-DR sera. Selected PLT-cells, specific for the HLA-D/DR antigens D/DRw1-8 and the local specificity D"H" were used. The results of the PLT-experiments were evaluated with the Normalized Median Response (NMR) method and the further procedure...

  20. Academic Position "Professor in Theoretical Chemistry" at the Department of Physical Chemistry, University of Sofia: Doc. Dr. Alya Tadjer

    Directory of Open Access Journals (Sweden)

    B.V. Toshev

    2011-05-01

    Full Text Available This is a review of the teaching and research activity of Dr. Alya Vitali Tadjer who applies for the academic position “Professor in Theoretical Chemistry” at the Department of Physical Chemistry, University of Sofia.

  1. Mobile Technology and Health Care, From NIH Director Dr. Francis S. Collins | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... version of this page please turn Javascript on. Mobile Technology and Health Care, From NIH Director Dr. Francis S. ... Contents Mobile health, or mHealth for short, uses mobile technologies for health research and healthcare delivery. At last ...

  2. After Dr. Manthey Left Town: What Happened When a Busy Mom Was Inspired to Host Her First Nursing Salon.

    Science.gov (United States)

    Belcik, Kim

    2017-02-01

    A busy nurse-mom describes her experience of being inspired to host her first nursing salon after attending a "mass" nursing salon by Dr. Marie Manthey at the Texas Nurses Association House of Delegates.

  3. Modeling the ternary complex TCR-Vbeta/CollagenII(261-273/HLA-DR4 associated with rheumatoid arthritis.

    Directory of Open Access Journals (Sweden)

    Maria Cristina De Rosa

    Full Text Available BACKGROUND: It is known that genetic predisposition to rheumatoid arthritis (RA is associated with the MHC class II allele HLA-DR4 and that residues 261-273 of type II collagen (huCollp261 represent an immunodominant T cell epitope restricted by the DR4 molecule. Despite recent advances in characterization of MHC and T cell receptor (TCR contacts to this epitope, the atomic details of TCR/huCollp261/HLA-DR4 ternary complex are not known. METHODOLOGY/PRINCIPAL FINDINGS: Here we have used computational modeling to get insight into this interaction. A three-dimensional model of the TCR Vbeta domain from a DR4(+ patient affected by RA has been derived by homology modeling techniques. Subsequently, the structure of the TCR Vbeta domain in complex with huCollp261/HLA-DR4 was obtained from a docking approach in conjunction with a filtering procedure based on biochemical information. The best complex from the docking experiments was then refined by 20 ns of molecular dynamics simulation in explicit water. The predicted model is consistent with available experimental data. Our results indicate that residues 97-101 of CDR3beta are critical for recognition of huCollp261/HLA-DR4 by TCR. We also show that TCR contacts on p/MHC surface affect the conformation of the shared epitope expressed by DR alleles associated with RA susceptibility. CONCLUSIONS/SIGNIFICANCE: This work presents a three-dimensional model for the ternary complex TCR-Vbeta/collagenII(261-273/HLA-DR4 associated with rheumatoid arthritis that can provide insights into the molecular mechanisms of self reactivity.

  4. Correlation between the Sensitivity to TRAIL and the Expression Level of DR5 on the Surface of Tumor Cells

    Institute of Scientific and Technical Information of China (English)

    Yuanfang Ma; Jun Zhang; Yueping Zhao

    2005-01-01

    OBJECTIVE To investigate the correlation between the sensitivity to the tumor necrosis factor- related apoptosis inducing ligand (TRAIL) and the level of expression of the death receptor 5 (DR5) on the surface of tumor cells.METHODS Anti-DR5 mAbs were used to directly detect the level of expression of DR5 on the surface of tumor cells. Using a TRAIL apoptosis kit and flow cytometry, the sensitivity of the tumor cells to TRAIL-induced apoptosis was determined and the correlation between DR5 expression and sensitivity to TRAIL analyzed.RESULTS The expression level of DR5 on the surface of different tumor cells was as follows: 97.9% in U937 cells, 95.1% in Jurkat cells, 93.8% in SW480 cells, 86.2% in HCT116 cells, 64.2% in HL-60 cells, 46.6% in Hela cells and 13.1% in K562 cells. The TRAIL-induced apoptotic rate was 72.6% in U937 cells, 85.2% in Jurkat cells, 78.6% in SW480 cells, 70.2% in HCT116 cells,60.1% in HL-60 cells, 45.4% in Hela cells and 12.3% in K562 cells. Statistical analysis showed there was a significant positive correlation (r=0.997, P<0.001) between DR5 expression and sensitivity to TRAIL.CONCLUSION The sensitivity of tumor cells to TRAIL is related to the level of expression of DR5 on the surface of tumor cells. These results confirm the importance of DR5 expression for induction of apoptosis by TRAIL.

  5. NCI's Dr. Barry Kramer on C-SPAN Over-Diagnosis and Treatment of Cancer | Division of Cancer Prevention

    Science.gov (United States)

    Dr. Barnett Kramer on Over-Diagnosis and Treatment of Cancer. Dr. Barnett Kramer talked about a study published in the Journal of American Medical Association on the changing the definition of cancer that could reduce unnecessary treatments for benign cancers. He also responded to telephone calls and electronic communications. For more information view the full article at: C-SPAN |

  6. MSeqDR: A Centralized Knowledge Repository and Bioinformatics Web Resource to Facilitate Genomic Investigations in Mitochondrial Disease.

    Science.gov (United States)

    Shen, Lishuang; Diroma, Maria Angela; Gonzalez, Michael; Navarro-Gomez, Daniel; Leipzig, Jeremy; Lott, Marie T; van Oven, Mannis; Wallace, Douglas C; Muraresku, Colleen Clarke; Zolkipli-Cunningham, Zarazuela; Chinnery, Patrick F; Attimonelli, Marcella; Zuchner, Stephan; Falk, Marni J; Gai, Xiaowu

    2016-06-01

    MSeqDR is the Mitochondrial Disease Sequence Data Resource, a centralized and comprehensive genome and phenome bioinformatics resource built by the mitochondrial disease community to facilitate clinical diagnosis and research investigations of individual patient phenotypes, genomes, genes, and variants. A central Web portal (https://mseqdr.org) integrates community knowledge from expert-curated databases with genomic and phenotype data shared by clinicians and researchers. MSeqDR also functions as a centralized application server for Web-based tools to analyze data across both mitochondrial and nuclear DNA, including investigator-driven whole exome or genome dataset analyses through MSeqDR-Genesis. MSeqDR-GBrowse genome browser supports interactive genomic data exploration and visualization with custom tracks relevant to mtDNA variation and mitochondrial disease. MSeqDR-LSDB is a locus-specific database that currently manages 178 mitochondrial diseases, 1,363 genes associated with mitochondrial biology or disease, and 3,711 pathogenic variants in those genes. MSeqDR Disease Portal allows hierarchical tree-style disease exploration to evaluate their unique descriptions, phenotypes, and causative variants. Automated genomic data submission tools are provided that capture ClinVar compliant variant annotations. PhenoTips will be used for phenotypic data submission on deidentified patients using human phenotype ontology terminology. The development of a dynamic informed patient consent process to guide data access is underway to realize the full potential of these resources.

  7. Zingiber officinale, Piper retrofractum and Combination Induced Apoptosis and p53 Expression in Myeloma and WiDr Cell Lines

    Directory of Open Access Journals (Sweden)

    HENY EKOWATI

    2012-09-01

    Full Text Available In previous studies, Zingiber officinale, Piper retrofractum, and the combination showed cytotoxic activity, induced apoptosis, and p53 expression of HeLa, T47D, and MCF-7 cell lines. This study was conducted to investigate the cytotoxic and apoptotic activity of Zingiber officinale (ZO, Piper retrofractum (PR, and the combination as well as their effect to p53 expression on Myeloma and WiDr cells. The powder of ZO, PR, and ZO + PR combination (1:1 were macerated with 96% ethanol for 3 x 24 hours. MTT cytotoxic assay was performed on Myeloma and WiDr cell lines. Apoptotic cells were stained with ethidium bromide and acridine orange. Imunohistochemical expression of p53 was examined on Myeloma and WiDr cell lines. Doxorubicin was used as positive control in all assays. Results showed that ZO, PR, and ZO + PR combination had cytotoxic activity on Myeloma cells with IC50 of 28, 36, and 55 mg/ml respectively and WiDr cell lines with IC50 of 74, 158, and 64 mg/ml respectively, induced apoptotic activity, and increased p53 expression on Myeloma and WiDr cells. These results suggest that ZO, PR, and their combination induced Myeloma and WiDr cells in apoptosis through p53 expression.

  8. A portrait of prefrontal lobotomy performed at the Royal Prince Alfred Hospital in Sydney by Dr Rex Money.

    Science.gov (United States)

    White, Richard T; McGee-Collett, Martin

    2016-10-01

    The objective of this article is to provide a portrait of prefrontal lobotomy performed at the Royal Prince Alfred Hospital, Sydney by the Head of Neurosurgery Dr Rex Money and to describe Dr Money's role in the promotion of psychosurgery in Sydney. We draw attention to an oral presentation by Dr Rex Money in 1951, a journal article written by Money, archival information held at the Royal Prince Alfred Hospital, including Dr Money's accounts of his travels and his reports regarding neurosurgery - both internationally and in Australia. Dr Rex Money performed a series of 13 prefrontal lobotomies between 1945 and 1951, and presented the theoretical basis for his series, his operative procedures and the outcomes at the annual meeting of its medical officers' association. Notwithstanding various deficiencies in his clinical research, Money's descriptions give a relatively comprehensive account of one of the first series of prefrontal lobotomies performed in Australia. The current article also describes Dr Money's contributions to the promotion of psychosurgery in Sydney, and illustrates the participation of a senior neurosurgeon and of a major Sydney teaching hospital during the psychosurgery saga. © The Royal Australian and New Zealand College of Psychiatrists 2016.

  9. Studying the biology of hope: An interview with Lee S. Berk, DrPH, MPH. Interview by Sheldon Lewis.

    Science.gov (United States)

    Berk, Lee S

    2007-01-01

    Dr Lee S. Berk is a pioneering medical researcher studying the neuroendocrine and immune effects of positive emotions. He is an associate professor of Health Promotion and Education, School of Public Health, and associate research professor of Pathology and Human Anatomy, School of Medicine, both at Loma Linda University in Loma Linda, California. Dr Berk is a fellow of the American College of Sports Medicine and the American Association for Integrative Medicine. He is also nationally board certified as a health education specialist and has served as a member of the board of directors for the American College of Lifestyle Medicine in Loma Linda, California. Dr Berk is a member of the editorial board of Advances in Mind Body Medicine. During the Society for Neurosciences' annual 2001 meeting Dr Berk presented and received major media coverage of a landmark paper entitled, "The Anticipation of a Laughter Eustress Event Modulates Mood States Prior to the Actual Humor Experience." More recently Dr Berk presented at the FASEB (Federation of American Societies for Experimental Biology) annual 2006 meeting in the American Physiological Society section another landmark paper entitled, "Beta-Endorphin and HGH Increase are Associated With Both the Anticipation and Experience of Mirthful Laughter," with further major media coverage. Recently, Dr Berk spoke about his work with Sheldon Lewis, editor in chief of Advances.

  10. Gambaran Laboratorium Leukemia Kronik di Bagian Penyakit Dalam RSUP Dr. M. Djamil Padang

    Directory of Open Access Journals (Sweden)

    Muthia Rendra

    2013-09-01

    Full Text Available AbstrakLeukemia merupakan penyakit keganasan sel darah yang berasal dari sumsum tulang ditandai oleh proliferasi sel-sel darah putih, dengan manifestasi adanya sel-sel abnormal dalam darah tepi. Pada tahun 2006, leukemia berada pada urutan ke-5 dari keseluruhan penderita kanker di Indonesia. Leukemia kronik merupakan leukemia yang paling sering terjadi pada dewasa dan lanjut usia. Secara umum leukemia kronik diklasifikasikan atas Leukemia Granulositik Kronik (LGK dan Leukemia Limfositik Kronik (LLK. Leukemia kronik yang perjalanannya lambat dan diiringi oleh gejala yang tidak khas, maka penelitian ini bertujuan untuk mengetahui gambaran laboratorium leukemia kronik di bagian Peyakit Dalam RSUP DR. M. Djamil Padang. Jenis penelitian ini adalah deskriptif retrospektif. Instrumen yang digunakan pada penelitian ini adalah data sekunder yang diperoleh dari Instalasi Rekam Medik RSUP Dr. M. Djamil Padang berupa data pasien leukemia kronik yang dirawat di Bagian Penyakit Dalam RSUP Dr. M. Djamil Padang sejak 1 Januari 2010 – 31 Desember 2012. Hasil penelitian ini menunjukkan bahwa dari 16 kasus leukemia granulositik kronik terdapat 37,5% pasien mengalami anemia sedang, 100% leukositosis, jumlah trombosit dapat menurun, normal, dan meningkat dengan presentase masing-masing 25%, 25%, dan 50%. Gambaran eritrosit sebagian besar normositik anisositosis. Separuh pemeriksaan darah tepi menunjukkan peningkatan persentasi mielosit, 31,25% menunjukkan peningkatan persentasi metamielosit dan eosinofil, serta sebagian besar menunjukkan presentasi blast. Sedangkan gambaran sumsum tulang hiperseluler, penekanan eritropoetik, mielopoetik hiperaktif, dan trombopoetik dalam batas normal. Leukemia limfositik kronik yang terdiri dari 1 kasus menunjukkan gambaran laboratorium berupa anemia sedang, leukositosis, trombositopenia, gambaran eritrosit nomokrom anisositosis, peningkatan jumlah leukosit, peningkatan jumlah limfosit, presentasi smudge cell, dan ditemukan

  11. Hubungan Status Gizi dengan Derajat Pneumonia pada Balita di RS. Dr. M. Djamil Padang

    Directory of Open Access Journals (Sweden)

    Mia Nurnajiah

    2016-01-01

    Full Text Available Abstrak                Pneumonia merupakan infeksi saluran pernapasan akut yang menjadi penyebab kematian utama pada balita di dunia, terutama di negara berkembang. Salah satu faktor risiko dari pneumonia adalah status gizi yang kurang. Tujuan penelitian ini adalah menentukan hubungan status gizi dan derajat pneumonia pada balita di RS. Dr. M. Djamil Padang. Desain penelitian adalah retrospektif analitik dengan pendekatan cross-sectional dan menggunakan uji statistik Chi-square.  Pengambilan data dilakukan dari Agustus hingga September 2014 di pusat rekam medis RS. Dr. M. Djamil Padang.  Subjek penelitian adalah 105 balita yang memenuhi kriteria inklusi dan eksklusi. Indikator status gizi yang digunakan adalah indkator BB/U kurva CDC rujukan WHO-NCHS. Subjek penelitian diklasifikasikan menurut derajat ringan-berat pneumonia. Sebanyak 51 balita (91,1% dengan status gizi baik menderita pneumonia (ringan-sedang dan 18 balita (8,9% status gizi kurang-buruk menderita pneumonia berat. Hasil penelitian p < 0,05 menunjukkan adanya hubungan bermakna antara status gizi dengan balita penderita pneumonia. Kesimpulan  penelitian ini ialah terdapat hubungan bermakna antara status gizi dan derajat pneumonia pada balita di RS. Dr. M. Djamil Padang. Sebagian besar balita dengan pneumonia derajat berat memiliki status gizi kurang dan buruk.Kata kunci: status gizi, derajat pneumonia, balita AbstractPneumonia is an acute respiratory infection which is the leading cause of children mortality in aged less than 5 years in the world, especially in developing countries.  One of pneumonia risk factors is undernutrition. The objective of this study  was to determine the relationship between nutritional status and pneumonia severity of children aged less than 5 years in RS. Dr. M. Djamil Padang. Type of this research is analytics retrospective with cross-sectional design and chi-square statistic test. The research was held from Agustus until September

  12. Diabetic Nephropathy Determinant Factor in Diabetes Mellitus at RSUD Dr. M. Soewandhie Surabaya

    Directory of Open Access Journals (Sweden)

    Rahmadany Isya Putri

    2015-01-01

    Full Text Available Non communicable diseases are an important health problem related with the shift in the pattern of death cause, which is from infectious diseases to non-infectious diseases. Diabetes mellitus (DM ranked 5 of the top 10 causes of non-infectious diseases in hospitals in Indonesia. If not properly controlled, DM can lead to chronic complications such as Diabetic Nephropathy (DN. This study, conducted at Internal Medicine Clinic, Outpatient Care, Dr. M. Soewandhie Hospital Surabaya, in June-July 2014, aimed to analyze correlation between non-clinical factors according to the concept of Hendrik L. Blum, such as compliance to treatment, education level, income, and social support for the incidence of DN in DM patients. This study was an observational analytic study with case-control design. Case samples in this study were DM patients who experienced DN complications and undergoing treatment at Internal Medicine Clinic, Outpatient Care, Dr. M. Soewandhie Hospital Surabaya, by 36 respondents. Control samples in this study were diabetic patients who did not experience complications DN undergoing treatment at Internal Medicine Clinic, Outpatient Care, Dr. M. Soewandhie Hospital Surabaya, by 36 respondents. Samples were taken by using a convenience sampling method. Relation streght analysis between dependent and independent variables used Contingency Coefficient by Chi Square test with 95% Confidence Interval (α=0.05. To determine the amount of risk between dependent and independent variables, we used OR (odds ratio calculation. The results showed that non-compliance to treatment (OR=2.8 with contigency coefficient 0.243, low education (OR=1.5 with contigency coefficient 0.091, income < District Minimum Wage (OR=1.21 with contigency coefficient 0.036, and not receiving social support (OR=1.65 with contigency coefficient 0.117. In conclusion, compliance to treatment, education level, income, and social support affect the incidence of DN in DM patients

  13. [Cloning and bioinformatics analysis of SLA-DR genes in Hunan Daweizi pigs].

    Science.gov (United States)

    Wang, Yan; Xing, Xiao-wei; Xue, Li-qun; Huang, Sheng-qiang; Wu, Xiao-li; Wang, Wei

    2009-09-01

    To evaluate the potential of Daweizi pigs as xenotransplantation dnors from pigs to humans by analyzing the characteristics of SLA-DR genes in Hunan Daweizi pigs. SLA-DRA and SLA-DRB genes were amplified by RT-PCR, cloned into pUCm-T vectors, sequenced and analyzed through BLAST in NCBI and related software in ExPASY. The SLA-DRA and SLA-DRB genes were 1 177 bp and 909 bp nucleotides in length, which contain opening reading frame (ORF) and encode 252 and 266 amino acids respectively. Comparing the SLA-DRA and SLA-DRB genes with their counterpart sequences of human, the homologies of amino acid sequences were 82% and 73% respectively. The amino acids in SLA DR alpha chain of Daweizi pigs from position 124 to 136, which bind to human CD4, showed only two differences with HLA DRA: a lle-Val change at position 127 and a Ser-Thr change at position 136. The amino acids in SLA DR beta chain of Daweizi pigs from position 134 to 148, which bind to human CD4, were identical with HLA-DRB. Further comparison with SLA sequences published in GenBank indicated that SLA-DRB gene found in Daweizi pigs has polymorphism while the homology of SLA-DRA gene is up to 100%. The cloned SLA-DRA and SLA-DRB in Hunan Daweizi pigs has high polymorphism with HLA-DRA and HLA-DRB in Human, indicates that Daweizi pigs have some advantages as xenotransplantation dnors from pigs to humans.

  14. Polymorphism at expressed DQ and DR loci in five common equine MHC haplotypes.

    Science.gov (United States)

    Miller, Donald; Tallmadge, Rebecca L; Binns, Matthew; Zhu, Baoli; Mohamoud, Yasmin Ali; Ahmed, Ayeda; Brooks, Samantha A; Antczak, Douglas F

    2017-03-01

    The polymorphism of major histocompatibility complex (MHC) class II DQ and DR genes in five common equine leukocyte antigen (ELA) haplotypes was determined through sequencing of mRNA transcripts isolated from lymphocytes of eight ELA homozygous horses. Ten expressed MHC class II genes were detected in horses of the ELA-A3 haplotype carried by the donor horses of the equine bacterial artificial chromosome (BAC) library and the reference genome sequence: four DR genes and six DQ genes. The other four ELA haplotypes contained at least eight expressed polymorphic MHC class II loci. Next generation sequencing (NGS) of genomic DNA of these four MHC haplotypes revealed stop codons in the DQA3 gene in the ELA-A2, ELA-A5, and ELA-A9 haplotypes. Few NGS reads were obtained for the other MHC class II genes that were not amplified in these horses. The amino acid sequences across haplotypes contained locus-specific residues, and the locus clusters produced by phylogenetic analysis were well supported. The MHC class II alleles within the five tested haplotypes were largely non-overlapping between haplotypes. The complement of equine MHC class II DQ and DR genes appears to be well conserved between haplotypes, in contrast to the recently described variation in class I gene loci between equine MHC haplotypes. The identification of allelic series of equine MHC class II loci will aid comparative studies of mammalian MHC conservation and evolution and may also help to interpret associations between the equine MHC class II region and diseases of the horse.

  15. Compressor Calorimeter Test of R-410A Alternatives R-32, DR-5, and L-41a

    Energy Technology Data Exchange (ETDEWEB)

    Shrestha, Som S [ORNL; Mahderekal, Isaac [ORNL; Sharma, Vishaldeep [ORNL; Abdelaziz, Omar [ORNL

    2013-02-01

    As a contribution to the AHRI Low-GWP Alternative Refrigerants Evaluation Program (AREP), this study compares performance of alternative refrigerants R32, DR-5, and L-41A to that of refrigerant R-410A (baseline) in a scroll compressor designed for air-conditioning and heat pump applications. Compressor calorimeter tests were performed to evaluate the performance of the lower-GWP alternative refrigerants in place of the common refrigerant R-410A in a 36,000 Btu/hr compressor calorimeter using a compressor having a nominal rated capacity of 21,300 Btu/hr. Tests were conducted over a suction dew point temperature range of 10 F to 55 F in 5 F increments and a discharge dew point temperature range of 70 F to 140 F in 10 F increments. All the tests were performed with 20 F superheat, 40 F superheat and 65 F suction temperature. A liquid subcooling level of 15 F was maintained for all the test conditions. The tests showed that performance of these three lower-GWP alternative refrigerants is comparable to that of R-410A. For the 20 F superheat and 15 F subcooling test conditions, EERs of R32, DR-5, and L-41A were 90% to 99%, 96% to 99%, and 94% to 101%, respectively, compared to that of R-410A. Similarly, cooling capacities of R32, DR-5, and L-41A were 98% to 103%, 92% to 96%, and 84% to 92%, respectively, compared to that of R-410A.

  16. Flouting maxim by sherlock holmes and dr. Watson in tv series Of sherlock season

    Directory of Open Access Journals (Sweden)

    Lina Affifatusholihah

    2017-04-01

    In running daily activities, people will always meet and interact with other people, and language is a medium that is used by humans to interact with each other. In a conversation or discussion, everyone should pay attention to the four maxims in order that there are no errors in communication. However, it is not uncommon that the four rules above are breached by the speakers. This is called non-observance of the maxims, and one of a non-observance of the maxims that often occurs in is flouting maxim. The aims of this paper are to describe types of maxims that are flouted by Sherlock Holmes and dr. Watson as well as to describe how the maxims are flouted in Sherlock TV series season 1. This research used qualitative descriptive method. The researcher classifies the utterances to know what kind of maxim which are flouted, categorizes those into the category based on the Grice’s theory of Cooperative Principle, namely: maxim of quantity, quality, relation and manner. The research procedure begin by searching the script in the internet, matching the utterances in the script and in film and sorting the utterances between Sherlock Holmes and dr. Watson as well observing every word or sentence which are flouted by the main characters. The findings find that all kinds of maxims are flouted by Sherlock and dr. Watson. The result of analysis shows that the maxim flouted when the speakers say something irrelevant; something roguishness or lied to hide the truth in the form of rhetorical question; the information becomes more or too informative than what is required; and something obscurity of expression, ambiguity, or unnecessary prolixity.

  17. 基于DR/CNS的月球车位置估计方法%An Approach of DR/CNS Based on Position Estimation of Lunar Rover

    Institute of Scientific and Technical Information of China (English)

    刘洋波; 刘红云; 裴福俊; 居鹤华

    2011-01-01

    月球车自主导航系统是完成月球探测任务的基础和关键,文中针对月球车导航的特殊要求设计了一种基于CNS/DR组合的月球车自主导航方法;首先依据月球车运动模型建立了系统状态方程,然后利用太阳敏感器测量的太阳高度角、航位推算系统输出的航向角速率和单位时间间隔内月球车行进距离作为量测信息建立了导航系统观测方程,再用扩展卡尔曼滤波(EKF)对导航信息进行最优估计;最后,对基于CNS/DR组合的月球车自主导航方法在计算机上进行了仿真分析;通过仿真结果可以说明文中提出的方法能获得较好的位置和航向估计精度,证明了该方法的正确性,是解决月球车自主导航问题一种有效的方法.%The autonomous navigation system is very fundamental and important to the lunar rover to complete the lunar exploration mission, so the CNS/DR based autonomous navigation system of lunar rover has been designed under the very spaical navigation enviroment. In this paper, a new approach of autonomous navigation for lunar rover based on Extended Kalman Filter (EKF) was described. The principle of this method was introduced, and the state space equation of system for lunar rover based on the rover motion model was developed. Then three measurements be implemented for observation vector, they are the elevation of sun that observed by sun sensor, angular velocity on the yew direction and lunar rover moving distance in a unit time step, that both the output of DR navigation system. The EKF has been implemented to get the optimal estimation of navigation information. Finally, the simulation of this method was finished. A simulation results demonstrated that this approach not only has good precision of position and head angle, but also the effective solution of lunar rover autonomous navigation.

  18. Revised cost estimate for the decommissioning of the reactor DR3

    DEFF Research Database (Denmark)

    2001-01-01

    The report describes a revision of the cost estimate for the decommissioning of the research Reactor DR 3 as described in the report Risø-R-1250(EN). Decommissioning of the Nuclear Facilities at Risø National Laboratory. Edited by Kurt Lauridsen. Therevision has been performed by the planning group...... in the Risø Decommissioning Department, and has been carried out as a discussion and evaluation of procedures methods and necessary resources to overcome the different phases of the the decommissioningtask of the Reactor....

  19. Faktor Risiko yang Berpengaruh terhadap Kejadian Berat Badan Lahir Rendah di RSUP Dr. M. Djamil Padang

    Directory of Open Access Journals (Sweden)

    Sagung Adi Sresti Mahayana

    2015-09-01

    Full Text Available Abstrak  Berat Badan Lahir Rendah (BBLR adalah bayi yang lahir dengan berat badan kurang dari 2500 g. BBLRmerupakan prediktor utama angka kesakitan dan kematian bayi. Tujuan penelitian ini adalah untuk menentukan faktorrisiko ibu, plasenta, janin dan lingkungan yang berpengaruh terhadap kejadian BBLR. Penelitian ini bersifat analitikdengan desain cross-sectional dengan mengumpulkan data retrospektif rekam medis ibu yang melahirkan bayi BBLRdi RSUP Dr. M. Djamil Padang dari Januari sampai Desember 2012. Pada 72 sampel yang didapatkan, faktor risikojanin dengan jenis kelamin laki-laki (61,1% dan status sosioekonomi rendah (52,8% memiliki proporsi yang lebihbesar pada kejadian BBLR. Analisis bivariat chi-square menunjukkan faktor risiko anemia (p=0,001 dan kelainanplasenta (p=0,049 memiliki hubungan statistik yang signifikan terhadap kejadian BBLR prematur dan dismatur.Pengaruh terbesar secara statistik terdapat pada faktor risiko anemia (p=0,001 dan paritas (p=0,022 pada analisismultivariat regresi logistik. Anemia, kelainan plasenta dan paritas merupakan faktor risiko yang berpengaruh terhadapkejadian BBLR prematur dan dismatur di RSUP Dr. M. Djamil Padang.Kata kunci: BBLR, prematur, dismatur, faktor risikoAbstract Low birthweight (LBW is a birth weight under 2500 g. LBW is a major predictor of infant morbidity and mortality.The objective of this study was to determine maternal, placental, fetal and environmental risk factors that influencingLBW. This was a cross-sectional study by obtaining retrospective datas from medical records of mother who deliveredLBW babies at RSUP Dr. M. Djamil Padang from January until December 2012 period. Male fetal sex (61.1% and lowsocioeconomic status (52.8% were found in high rates on total 72 cases of LBW. Chi-square test showed anemia(p=0.001 and placental abnormalities (p=0.049 were statistically significant in LBW with premature and dysmature.Logistic regression test indicates anemia (p=0.001 and parity (p=0

  20. Dr. Robert Clark studies levels of radiation Skylab 2 crew was exposed to

    Science.gov (United States)

    1973-01-01

    In the Radiation Counting Laboratory sixty feet underground at JSC, Dr. Robert S. Clark prepares to load pieces of iridium foil - sandwiched between plastic sheets - into the laboratory's radiation detector. The iridium foil strips were worn by the crew of the second Skylab flight in personal radiation dosimeters throughout their 59.5 days in space. Inside the radiation detector assembly surrounded by 28 tons of lead shielding, the sample will be tested to determine the total neutron dose to which the astronauts were exposed during their long stay aboard the space station.