L'ennui dans quelques romans de Julien Green : du « violent dégoût de tout » à « l’effroi d’être au monde »

OpenAIRE

Andevert, Anne-Laure

2015-01-01

This thesis aims at studying how boredom is depicked in five novels – Mont-Cinère, Adrienne Mesurat, Minuit, Le Malfaiteur, Le Mauvais Lieu – and how differently Julien Green painted it. In a first part, our analysis of the Greenian boredom from within and without has highlighted his characters’ internal alienation mirroring their inability to live. Indeed, studying the characters’ environment gives some insight into the scope of boredom. The town then becomes the canvass on which their bored...

Quand devient-on vieille ? Femmes, âge et travail au Québec, 1940-1980 d'Aline Charles

Directory of Open Access Journals (Sweden)

Hélène David

2009-11-01

Full Text Available Cet ouvrage, constitué de deux parties principales, vise à faire émerger de la méconnaissance actuelle des « vieillesses de femmes actives » ainsi qu’à documenter la naissance et l’essor d’une retraite féminine. Aline Charles amorce son propos avec limpidité en expliquant la nécessité de conjuguer des analyses constructivistes sur trois objets distincts, la vieillesse, les femmes et le travail, afin de pouvoir cerner des fins de vies professionnelles de longue durée ainsi que l’accès à la ret...

Igneous Complexes of the Orochenka Caldera of the East Sikhote-Alin Belt: U-Pb (SHRIMP) Age, Trace and Rare Earth Element Composition, and Au-Ag Mineralization

Science.gov (United States)

Sakhno, V. G.; Kovalenko, S. V.

2018-04-01

New data are presented on the geology and composition of volcanic and intrusive rocks of the Orochenka caldera, which is located in the western part of the East Sikhote Alin volcanic belt. The SHRIMP and ICP MS age of zircons of volcanic and intrusive rocks, respectively, and the composition of the volcanic rocks allow comparison of these complexes with volcanic rocks of the eastern part of the volcanic structure. New data indicate the period of transition between subduction to transform regimes.

Les traductions russes de La Légende de Saint Julien L’Hospitalier

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Svetlana Maire

2012-02-01

Full Text Available Les œuvres de Gustave Flaubert étaient et restent toujours populaires auprès du lectorat russe. La Légende de Saint Julien l’Hospitalier, parue en 1876, a suscité l’intérêt d’un grand nombre de traducteurs. Ivan Turgenev fut le premier à réaliser une traduction officielle en russe de la Légende en 1877. Par la suite, d’autres versions ont suivi. Cet article propose l’analyse de trois traductions réalisées à trois périodes différentes par trois grandes personnalités de la littérature russe, Ivan Turgenev, Alexandr Blok et Maximilian Vološin. Chacun d’eux a sa propre méthode de traduction, utilise ses propres procédés afin de restituer au mieux l’effet de stylisation créé par Gustave Flaubert. La distance temporelle qui existe entre les trois traductions suppose que chacune d’elles suive les tendances littéraires propres à son époque. Ainsi, l’analyse comparative des traductions sera menée sous un angle diachronique. Par ailleurs, la traduction de chacun d’eux reflète les tendances dominantes dans le développement des différentes conceptions du métier du traducteur et plus particulièrement sur le travail de stylisation historique.The Russian reader has always been lost in admiration at Gustave Flaubert’s production, which is particularly style-worked and of a high literary quality. The Legend of St. Julian the Hospitaller, wrote in 1876, is marked out by stylistic treasures where the form is also important as the content. Consequently, this text represents a difficult translation exercise. However, the text has always aroused interest of translators. It was in the year 1877 that Ivan Turgenev first translated it into Russian and after that various versions with distinctive features have been turning up. This paper consists on examining three versions carried out for the three different periods by three eminent personalities of the Russian literature, Ivan Turgenev, Alexandr Blok, Maximilian

Response of Landscapes of the Sikhote-Alin Western Slopes to the Middle-Late Holocene Climatic Changes

Science.gov (United States)

Razzhigaeva, N. G.; Ganzey, L. A.; Panichev, A. M.; Grebennikova, T. A.; Mokhova, L. M.; Kopoteva, T. A.; Kudryavtseva, E. P.; Arslanov, Kh. A.; Maksimov, F. E.; Starikova, A. A.; Zakusin, S. V.

2017-12-01

The response of landscape biotic components of the western slope of the Sikhote-Alin Mountains (Bikin River middle flow) to the Middle-Late Holocene climate changes is discussed. The paleoreconstruction object was the Krasny Yar mari, which developed under the control of multidirectional short-term climatic changes. The last millennium was marked by particularly rapid and frequent changes in the local landscapes. The closely spaced orographic barrier strongly affected the development of biotic components and changes in the swamp hydrological regime. The moisture dynamics within the river catchment considerably controlled the development and change of the peat-forming plants. Several stages of the mari development were reconstructed; each began from the accumulation of eutrophic peat. It was followed by the transitional eutrophic-mesotrophic stage, with a higher role of atmospheric supply. The larch forests appeared in this part of the valley within the Atlantic-Subboreal cooling period. Korean pine developed in the forest vegetation in the low mountain relief at the beginning of the Subboreal and became one of the leading trees 2.6-2.3 ka BP. The lower role of the Korean pine and birch forest expansion in the first half of the Subatlantic could be related to the fires. The broadleaf-Korean pine forests became widespread in the Medieval Warm Period. Local swamp landscapes changed dramatically in the Little Ice Age, while the slope vegetation was not subject to any major changes. The landscapes were also affected by the fires, which became more frequent. The derivative communities with birch appeared on the mari. Moreover, this part of the valley was occasionally subject to heavy flooding.

Effect of vitamin C on collagen biosynthesis and degree of ...

African Journals Online (AJOL)

STORAGESEVER

2008-06-17

Jun 17, 2008 ... S. R. Sharma1, R. Poddar1, P. Sen2, and J. T. Andrews1,3*. 1Applied Optics ..... Boyera N, Galey I, Bernand BA (1998). Effect of vitamin C ... Humbert P, Nusgens BV, Rougier A, Colige AC, Haftek M, Lambert CA,. Richard A ...

Study of the influence of gravity on the thermodynamic equilibrium of a liquid alloy, and on its solidification: application to eutectic Al-Ge and monotectic Al-In alloys

International Nuclear Information System (INIS)

Vinet, Bernard

1981-01-01

After having recalled the meaning of gravity, this research thesis addresses the study of movements within the Earth gravity field to assess accelerations for a centrifuged system, and to describe conditions which create weightlessness. The various actions of gravity on fluid phases are analysed by highlighting phenomena of convection and segregation. In a second part, the author addresses the issue of local order. The third part addresses the influence of gravity conditions on the distribution of components of a binary liquid alloy in thermodynamic equilibrium. The fourth part addresses experimental means. The next parts address the eutectic Al-Ge alloy and the monotectic Al-In alloy. Results obtained for liquid alloy are presented, and the author analyse segregations which appeared during solidification in gravity conditions between 40 and 100 g. The influence of these conditions of the structure of both alloys is then studied

Evaluation of left atrial linear ablation using contiguous and optimized radiofrequency lesions: the ALINE study.

Science.gov (United States)

Wolf, Michael; El Haddad, Milad; Fedida, Joël; Taghji, Philippe; Van Beeumen, Katarina; Strisciuglio, Teresa; De Pooter, Jan; Lepièce, Caroline; Vandekerckhove, Yves; Tavernier, René; Duytschaever, Mattias; Knecht, Sébastien

2018-01-08

Achieving block across linear lesions is challenging. We prospectively evaluated radiofrequency (RF) linear ablation at the roof and mitral isthmus (MI) using point-by-point contiguous and optimized RF lesions. Forty-one consecutive patients with symptomatic persistent AF underwent stepwise contact force (CF)-guided catheter ablation during ongoing AF. A single linear set of RF lesions was delivered at the roof and posterior MI according to the 'Atrial LINEar' (ALINE) criteria, i.e. point-by-point RF delivery (up to 35 W) respecting strict criteria of contiguity (inter-lesion distance ≤ 6 mm) and indirect lesion depth assessment (ablation index ≥550). We assessed the incidence of bidirectional block across both lines only after restoration of sinus rhythm. After a median RF time of 7 min [interquartile range (IQR) 5-9], first-pass block across roof lines was observed in 38 of 41 (93%) patients. Final bidirectional roof block was achieved in 40 of 41 (98%) patients. First-pass block was observed in 8 of 35 (23%) MI lines, after a median RF time of 8 min (IQR 7-12). Additional endo- and epicardial (54% of patients) RF applications resulted in final bidirectional MI block in 28 of 35 (80%) patients. During a median follow-up of 396 (IQR 310-442) days, 12 patients underwent repeat procedures, with conduction recovery in 4 of 12 and 5 of 10 previously blocked roof lines and MI lines, respectively. No complications occurred. Anatomical linear ablation using contiguous and optimized RF lesions results in a high rate of first-pass block at the roof but not at the MI. Due to its complex 3D architecture, the MI frequently requires additional endo- and epicardial RF lesions to be blocked. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2018. For permissions, please email: journals.permissions@oup.com.

Population dynamics of Amur tigers (Panthera tigris altaica) in Sikhote-Alin Biosphere Zapovednik: 1966-2012.

Science.gov (United States)

Miquelle, Dale G; Smirnov, Evgeny N; Zaumyslova, Olga Yu; Soutyrina, Svetlana V; Johnson, Douglas H

2015-07-01

In 2010, the world's tiger (Panthera tigris) range countries agreed to the goal of doubling tiger numbers over 12 years, but whether such an increase is biologically feasible has not been assessed. Long-term monitoring of tigers in Sikhote-Alin Biosphere Zapovednik (SABZ), Russia provided an opportunity to determine growth rates of a recovering population. A 41-year growth phase was followed by a rapid decline in tiger numbers. Annual growth rates during the growth phase averaged 4.6%, beginning near 10% in the earliest years but quickly dropping below 5%. Sex ratio (females per male) mirrored growth rates, declining as population size increased. The rapid decline from 2009 to 2012 appeared to be tied to multiple factors, including poaching, severe winters and disease. Reproductive indicators of this population are similar to those of Bengal tiger populations, suggesting that growth rates may be similar. These results suggest that, first, tiger populations likely in general grow slowly: 3-5% yearly increases are realistic and larger growth rates are likely only when populations are highly depressed, mortality rates are low and prey populations are high relative to numbers of adult females. Second, while more research is needed, it should not be assumed that tiger populations with high prey densities will necessarily grow more quickly than populations with low prey densities. Third, while growth is slow, decline can be rapid. Fourth, because declines can happen so quickly, there is a constant need to monitor populations and be ready to respond with appropriate and timely conservation interventions if tiger populations are to remain secure. Finally, an average annual growth rate across all tiger populations of 6%, required to reach the Global Tiger Initiative's goal of doubling tiger numbers in 12 years, is a noble but unlikely scenario. © 2015 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and Wiley Publishing Asia

COMPARISON OF PRODUCTION PARAMETERS BETWEEN THE FIRST GENERATION OF A-LINE IMPORTED AND BRED GILTS ON THE NUCLEUS FARM VELIKA BRANJEVINA

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Dragica Dubravac

2013-06-01

Full Text Available Comparison of productive parameters of two analyzed groups (the first generation of imported gilts and the gilts born on the domestic farm was conducted on a nucleus farm that imported the gilt lines from the TOPIGS breeding program. For the purposes of the nucleus pig farm, TOPIGS gilts were imported from Netherlands. The nucleus farm where the analysis of the two groups’ productive parameters was conducted imported the ancestral and grandfather lines to produce the parenting generation TOPIGS 40 sows which are bred with a Pietrain line of boars. The TOPIGS 40 sow is an animal based on A-line and B-line characterized by high fertility rate, excellent maternal characteristics, good capacity for growth, and quality meaty body. The analysis of productive parameters of the two observed groups of gilts (the first generation of 105 imported gilts and 88 gilts born on the domestic farm resulted in significantly higher number of total born, born alive and weaned piglets after the first farrowing (P<0.001 as well as significantly higher number of total born and born alive piglets at third farrowing (P<0.05. The results of the observed qualities confirm the fact that, apart from the unquestionable genetic potential, other factors such as adaptation, accommodation conditions, microclimate, nutrition, and management have a significant effect on the increase of production results.

2267-IJBCS -Article-Julien Avakoudjo

African Journals Online (AJOL)

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Les forêts galeries dégradées quasi inexistantes en 1972 se sont reconstituées à partir de 1990 et sont passées de 0,60% ...... Etudes Démographiques, Institut National de la Statistique et de l'Analyse. Economique: Cotonou. Kagoné H. 2004. Etat des lieux de la transhumance dans la zone d'influence du. Parc W du fleuve ...

Influence of Plum Rootstocks on the Content of Reducing Sugars in the Annual Shoots of Cultivar ‘Kubanskaya Kometa’

Directory of Open Access Journals (Sweden)

Dēķena Dzintra

2014-12-01

Full Text Available The lack of suitable plum rootstocks for Baltic conditions has become a problem during recent years due to changing climatic conditions. Rapid temperature fluctuations between freezing and thawing are occurring more frequently. The winter-hardiness of rootstocks is essential for overwintering of trees in such conditions. The content of accumulated reducing sugars is an important physiological factor influencing wintering ability of trees. The dynamics of reducing sugars was investigated during two winter seasons (2010/2011 and 2011/2012 in one-year-old ‘Kubanskaya Kometa’ (Prunus x rossica Erem. hybrid plum shoots from two orchards planted in 2001 at Pūre Horticultural Research Centre (Latvia and Polli Horticultural Research Centre (Estonia. Cultivar ‘Kubanskaya Kometa’ was grafted on eight clonal rootstocks: ‘St. Julien A’, ‘Brompton’ cuttings, ‘Ackermann’, ‘Pixy’, GF8/1, G5/22, GF655/2, ‘Hamyra’ and eight seedling rootstocks: ‘St. Julien INRA 2’, ‘St. Julien d’Orleans’, ‘St. Julien Noir’, ‘Brompton’ seedlings, ‘Wangenheims Zwetsche’, ‘St. Julien Wädenswill’, ‘Myrobаlan’ and Prunus cerasifera var. divaricata. Trees were planted at 5×3 m spacing in four replications per rootstock with three trees per plot. Shoot samples were harvested five times during the winter period. The concentration of reducing sugars (mg g-1 dry weight was determined with Bertran’s method. Significant differences in concentration of reducing sugar were found between samples coming from different locations and in two seasons. The maximum concentration of reducing sugar was found in December or January depending on growing location and meteorological conditions

Yield and Depth of Burial Hydrodynamic Calculations in Granodiorite: Implications for the North Korean Test Site

Science.gov (United States)

2011-09-01

the existence of a test site body wave magnitude (mb) bias between U. S. and the former Soviet Union test sites in Nevada and Semipalatinsk . The use...YIELD AND DEPTH OF BURIAL HYDRODYNAMIC CALCULATIONS IN GRANODIORITE:IMPLICATIONS FOR THE NORTH KOREAN TEST SITE Esteban Rougier, Christopher R...Korean test site and the May 2009 test . When compared to the Denny and Johnson (1991) and to the Heard and Ackerman (1967) cavity radius scaling models

Improved Soil Erosion and Sediment Transport in GSSHA

Science.gov (United States)

2010-08-01

the USLE soil erodibility factor (0-1), soil cropping factor (0-1) and conservation factor (0-1) in the development by Julien (1995). The use of one...factor K represents a departure from Julien (1995), who used all three factors from the Universal Soil Loss Equation ( USLE ). This departure is justi...runoff using a research-quality data set. BACKGROUND: GSSHA simulates overland soil erosion and outputs erosion and deposition for any size class of

Cine Club

CERN Multimedia

Cine Club

2013-01-01

Thursday 21 February 2013 at 20:00 CERN Main Auditorium Joe Strummer : The Future is Unwritten Directed by Julien Temple (Ireland/UK, 2007) With:  Joe Strummer, Steve Jones, Mick Jones Original version english; 124 minutes As the front man of the Clash from 1977 onwards, Joe Strummer changed people’s lives forever. Four years after his death, his influence reaches out around the world, more strongly now than ever before. In “The Future Is Unwritten”, from British film director Julien Temple, Joe Strummer is revealed not just as a legend or musician, but as a true communicator of our times. Drawing on both a shared punk history and the close personal friendship which developed over the last years of Joe’s life, Julien Temple’s film is a celebration of Joe Strummer - before, during and after the Clash. For information:  http://cineclub.web.cern.ch/Cineclub/ Projection from DVD – entrance 2 CHF

Large Data Visualization with Open-Source Tools

CERN Multimedia

CERN. Geneva

2015-01-01

Visualization and post-processing of large data have become increasingly challenging and require more and more tools to support the diversity of data to process. In this seminar, we will present a suite of open-source tools supported and developed by Kitware to perform large-scale data visualization and analysis. In particular, we will present ParaView, an open-source tool for parallel visualization of massive datasets, the Visualization Toolkit (VTK), an open-source toolkit for scientific visualization, and Tangelohub, a suite of tools for large data analytics. About the speaker Julien Jomier is directing Kitware's European subsidiary in Lyon, France, where he focuses on European business development. Julien works on a variety of projects in the areas of parallel and distributed computing, mobile computing, image processing, and visualization. He is one of the developers of the Insight Toolkit (ITK), the Visualization Toolkit (VTK), and ParaView. Julien is also leading the CDash project, an open-source co...

2008-IJBCS-Article Kalpy Julien Coulybaly

African Journals Online (AJOL)

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éclairée par 4 ampoules néon MAZDA. FLUOR M2TF 36W/LJ de 1,2 m de long, de. 32 Watt produisant une lumière type lumière du jour de 3350 lumens chacun. D'où une intensité lumineuse globale de 706,66 lux. Une seconde expérience avec une légère modification de la composition des milieux. Bold et Conways, une ...

1284-IJBCS-Article-Momou Julien Kouassi

African Journals Online (AJOL)

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evolution of these pollutions effects may jeopardize the sustainability of the Abidjan lagoon system. ... of habitat and impose serious ecological threats and impact the ..... representative of the functional group carrying ... induce the loss of fish.

O realismo mágico - uma dimensão da literatura francesa do Século XX

OpenAIRE

Pereira, Maria Eugénia Tavares

2005-01-01

Pierre Mac Orlan, Jules Supervielle, Alain-Fournier, Jean Cocteau, Jean Giono, Marcel Aymé, André Dhôtel, Julien Green, Julien Gracq, Yves Bonnefoy, Michel Tournier foram os autores do século XX que elegemos, de entre muitos outros, para, através da releitura das suas obras – Le Quai des brumes, L’Enfant de la haute mer, Le Grand Meaulnes, Les Enfants terribles, Mort d’un personnage, Le Passe-muraille, Le Pays où l’on n’arrive jamais, Le Visionnaire, Au Château d’Argol, L’Ar...

Climate change - the impacts

International Nuclear Information System (INIS)

Reysset, Bertrand; Billes-Garabedian, Laurent; Henique, Julien; Pascal, Mathilde; Pirard, Philippe; Motreff, Yvon; Barbault, Robert; Weber, Jacques; Gate, Philippe; Salagnac, Jean-Luc; Desplat, Julien; Kounkou-Arnaud, Raphaelle

2012-01-01

This special dossier about the impacts of climate change is made of 6 contributions dealing with: the mitigation of climate effects and how to deal with them (Bertrand Reysset); how to dare and transmit (Laurent Billes-Garabedian); littoral risks, the Pas-de-Calais example (Julien Henique); extreme meteorological events and health impacts (Mathilde Pascal, Philippe Pirard, Yvon Motreff); Biodiversity and climate: the janus of global change (Robert Barbault, Jacques Weber); adapting agriculture to dryness and temperatures (Philippe Gate); Paris and the future heats of the year 2100 (Jean-Luc Salagnac, Julien Desplat, Raphaelle Kounkou-Arnaud)

77 FR 38793 - Northern Natural Gas Company; Notice of Intent To Prepare an Environmental Assessment for the...

Science.gov (United States)

2012-06-29

... the environmental impacts of the A-Line Abandonment Project (Project) which would include the... Carson Counties, Texas; Beaver County, Oklahoma; and Kiowa and Clark Counties, Kansas. This EA will be..., Ochiltree County, Texas. The second segment (the Beaver to Mullinville A-line) is about 88 miles long and...

Validity and reliability of a novel slow cuff-deflation system for noninvasive blood pressure monitoring in patients with continuous-flow left ventricular assist device.

Science.gov (United States)

Lanier, Gregg M; Orlanes, Khristine; Hayashi, Yacki; Murphy, Jennifer; Flannery, Margaret; Te-Frey, Rosie; Uriel, Nir; Yuzefpolskaya, Melana; Mancini, Donna M; Naka, Yoshifumi; Takayama, Hiroo; Jorde, Ulrich P; Demmer, Ryan T; Colombo, Paolo C

2013-09-01

Doppler ultrasound is the clinical gold standard for noninvasive blood pressure (BP) measurement among continuous-flow left ventricular assist device patients. The relationship of Doppler BP to systolic BP (SBP) and mean arterial pressure (MAP) is uncertain and Doppler measurements require a clinic visit. We studied the relationship between Doppler BP and both arterial-line (A-line) SBP and MAP. Validity and reliability of the Terumo Elemano BP Monitor, a novel slow cuff-deflation device that could potentially be used by patients at home, were assessed. Doppler and Terumo BP measurements were made in triplicate among 60 axial continuous-flow left ventricular assist device (HeartMate II) patients (30 inpatients and 30 outpatients) at 2 separate exams (360 possible measurements). A-line measures were also obtained among inpatients. Mean absolute differences (MADs) and correlations were used to determine within-device reliability (comparison of second and third BP measures) and between-device validity. Bland-Altman plots assessed BP agreement between A-line, Doppler BP, and Terumo Elemano. Success rates for Doppler and Terumo Elemano were 100% and 91%. Terumo Elemano MAD for repeat SBP and MAP were 4.6±0.6 and 4.2±0.6 mm Hg; repeat Doppler BP MAD was 2.9±0.2 mm Hg. Mean Doppler BP was lower than A-line SBP by 4.1 (MAD=6.4±1.4) mm Hg and higher than MAP by 9.5 (MAD=11.0±1.2) mm Hg; Terumo Elemano underestimated A-line SBP by 0.3 (MAD=5.6±0.9) mm Hg and MAP by 1.7 (MAD=6.0±1.0) mm Hg. Doppler BP more closely approximates SBP than MAP. Terumo Elemano was successful, reliable, and valid when compared with A-line and Doppler.

Geology, mineralization, and fluid inclusion characteristics of the Skrytoe reduced-type W skarn and stockwork deposit, Sikhote-Alin, Russia

Science.gov (United States)

Soloviev, Serguei G.; Kryazhev, Sergey G.

2017-08-01

The Skrytoe deposit (>145 Kt WO3, average grade 0.449% WO3) in the Sikhote-Alin orogenic system (Eastern Russia) is situated in a metallogenic belt of W, Sn-W, Au, and Au-W deposits formed in a late to post-collisional tectonic environment after cessation of active subduction. It is localized within a mineralized district of reduced-type skarn W and veined Au (±W) deposits and occurrences related to the Early Cretaceous ilmenite-series plutonic suite. The deposit incorporates large stockworks of scheelite-bearing veinlets related to propylitic (amphibole, chlorite, quartz) and phyllic (quartz, sericite, albite, apatite, and carbonate) hydrothermal alteration. The stockwork cuts flat-lying mafic volcanic rocks and limestone partially replaced by pyroxene skarn that host the major W orebodies. Scheelite is associated with pyrrhotite and/or arsenopyrite, with minor chalcopyrite and other sulfide minerals; the late phyllic stage assemblages hosts Bi and Au mineralization. The fluid evolution included low-salinity moderate-temperature, moderate-pressure (˜370-390 °C, ˜800 bars) methane-dominated carbonic-aqueous fluids that formed post-skarn propylitic alteration assemblages. Then, at the phyllic stage, there has been an evolution from methane-dominated, moderate-temperature (330-360 °C), low-salinity (<12.3 wt% NaCl equiv.) fluids forming the early quartz-sericite-albite-arsenopyrite assemblage, through lower temperature (290-330 °C) methane-dominated, low-salinity (˜9-10 wt% NaCl equiv.) fluids forming the intermediate quartz-sericite-albite-scheelite-pyrrhotite assemblage, to yet lower temperature (245-320 °C) CO2-dominated carbonic-aqueous low-salinity (˜1-7 wt% NaCl equiv.) fluids forming the late quartz-sericite-sulfide-Bi-Au assemblage. Recurrent fluid immiscibility (phase separation) and cooling probably affected W solubility and promoted scheelite deposition. The stable isotope data support a sedimentary source of carbon (δ13Cfluid = ˜-21 to -10 �

Valgusinstallatsioon WTC mälestuseks

Index Scriptorium Estoniae

2001-01-01

Ameerika kunstnikud Paul Myoda ja Julien LaVerdiere kavandavad World Trade Center'i kokkuvarisenud tornide asemele projetseerida kaks valgussammast, pealkirjastades oma projekti "Viirastuslikud tornid"

Surface Observation Climatic Summaries (SOCS) for Volk Field ANGB, Wisconsin.

Science.gov (United States)

1989-05-01

LIMIT(S), EITHER SEPARATELY OR IN ANY C󈧒RINATI"Pl. TOTALS PROGRESS FROM RIGHT Tl LEFT AND PRUM BOTTOM1 T2 TOP. TOJ OETER Iljt CEILINS ALINE, REFER TO...THE cATREME7 RIGTHAND CO]LUMN (ZER? VISI3ILITY). TO DETERM’INE VISIBI1LITY ALINE, R’EFER TO THE BOTTOM ROW (ZEkO CEILINGS). OETER 𔃾INE THE P9F THAT

Assessment of the Long-tailed Goral (Naemorhedus caudatus: Bovidae population status in the Sikhote-Alin Reserve using camera-traps

Directory of Open Access Journals (Sweden)

Olga Yu. Zaumyslova

2017-05-01

Full Text Available The Long-tailed goral (Naemorhedus caudatus is a rare mountain ungulate animal species with a mosaic range. In the Sikhote-Alin Reserve, the goral is located at the northern limit of its distribution. The main part of its population is concentrated in the coastal area, in the Abrek natural landmark. In the early XX century, the goral occupied another small area along the coast – 20 km south of the Abrek natural landmark. Currently, the total area of species' habitats is only 7.1 km2. The aim of this study was to assess the population size, population density and some demographic parameters of the goral population. Also, we aimed to evaluate the effectiveness of the photo-trap method which is a new approach to the study and monitoring of this rare species. Accounting studies in the Abrek natural landmark were carried out in October 2014 – January 2015 (1401 trap-days; also, at the same time we worked in the second area during three seasons (2014–2017, 1326 trap-days. Estimation of the abundance and annual survival of the goral has been carried out using stochastic «capture – recapture» models presented in the software MARK. In the Abrek natural landmark for an effective area of 4 km2 (63% of this habitat's area, the average density of the goral population was 15.4 animals per km2 (CI 95% = 14.6–18.2 individuals per km2, in the second area (0.7 km2 completely accounted – 21.0 individuals per km2 (CI 95% = 20.1–28.6 individuals per km2. The total abundance of goral individuals in the Reserve remains, apparently, at the level of the late 1980s. And currently it is about 110–140 individuals. According to our preliminary data, the total annual survival in the first year was 0.73 (CI 95% = 0.41–0.91, and by the end of the second year it was 0.72 (CI 95% = 0.31–0.93. Female animals have prevailed in the population structure, and the sex ratio for adult animals was 1:1.5. The fertility rate was 0.61. In comparison with the data

Translations on Narcotics and Dangerous Drugs No. 271

Science.gov (United States)

1976-11-11

Worth 25,000 Kyats Seized in Rangoon (MYANMA ALIN, 18 Oct 76) 10 Marihuana Burned in Okto (MYANMA ALIN, 2 Oct 76) 11 MALAYSIA American... Marihuana , Cocaine Pushers, Addicts Arrested (EL TIEMPO, 23 Sep 76) 29 Briefs Drug Ring Smashed 31 Drug Hauls and Arrests 31 Drug Traffickers Arrested...lead of the Labor Governments in New South Wales and South Australia in moves to legalise marihuana ," he said. A submission by the Australian

Department of Clinical Investigation Annual Research Progress Report, Fiscal Year 1993. Volume 2

Science.gov (United States)

1993-10-01

A-5-90 Production of Mouse Positive and Negative Control Slides for 382 Use in Rabies FRA Test. (0) A-7-90 Clinical Investigation on the...Possible 402 Diagnostic and Therapeutic Manuever as Tested in a Mouse Model Utilizing PET Scanning. (0) A-93-04 Production of Monoclonal Antibodies to...xlv Project Page Number POG 9005 ALinC 15: Dose Intensification of Methotrexate and 583 6- Mercaptopurine for ALL in Childhood. (0) P00 9006 ALinC 15

Fulltext PDF

Indian Academy of Sciences (India)

for solving fuzzy solid transportation problem are pointed out and to overcome these ... To deal quantitatively with imprecise information, the concepts and techniques of ...... Julien B 1994 An extension to possibilistic linear programming.

The GEONET by the Geospatial Information Authority of Japan (GSI)

DEFF Research Database (Denmark)

Nørremark, Michael

2017-01-01

Memorandum for Deloitte (on behalf of Styrelsen for Dataforsyning og Effektivisering: ’Analyse af behovet for udarbejdelsen af en fællesoffentlig datainfrastruktur for stedbestemt data’), Copenhagen, att. Julien Jean-Marie Rousselon Kosloff...

Transboundary Water Resources in Southern Africa: Conflict or cooperation?

CSIR Research Space (South Africa)

Patrick, MJ

2006-01-01

Full Text Available Literature suggests a linkage between internationally shared water resources and conflict potential. Anthony R. Turton, Marian J. Patrick and Frederic Julien examine transboundary water resource management in southern Africa, showing that empirical...

49 CFR 213.55 - Alinement.

Science.gov (United States)

2010-10-01

... the mid-ordinate from a 31-foot chord 2 may not be more than—(inches) The deviation of the mid-ordinate from a 62-foot chord 2 may not be more than—(inches) Class 1 track 5 3 N/A 5 Class 2 track 3 3 N/A...

Quantifying biometric life insurance risks with non-parametric smoothing methods

NARCIS (Netherlands)

Tomas, J.

2013-01-01

Julien Tomas beschrijft verdelingsvrije afrondingsmethoden van de sterfte-ervaring bij levensverzekeringen. Net als parametrische methoden neigen ook deze methoden naar onzuivere schattingen, maar zodanig dat het mogelijk is een grotere onzuiverheid op te laten wegen tegen een lagere

DEFINIŢIA LEGISLATIVĂ A NOŢIUNII „PERSOANĂ CU FUNCŢIE DE DEMNITATE PUBLICĂ”: ANALIZA EVOLUŢIEI

Directory of Open Access Journals (Sweden)

Sergiu BRÎNZA

2017-01-01

Full Text Available Scopul investigaţiei de faţă rezidă în analiza evoluţiei pe care a parcurs-o definiţia legislativă a noţiunii „persoană cu funcţie de răspundere”. Se relevă că dispoziţia de la alin.(3 art.123 CP RM a fost supusă unor amendamente prin Legea nr.318/2013 şi prin Legea nr.152/2016. Se stabileşte că în rezultatul acestor amendamente: din respectiva dispoziţie a fost exclus textul „consilierul local; deputatul în Adunarea Populară a Găgăuziei;”; în dispoziţia alin.(3 art.123 CP RM, cu­vin­tele „în condiţiile legii” au fost substituite cu cuvintele „altă persoană cu funcţie de demnitate publică stabilită prin lege”. Se demonstrează că consilierul local şi deputatul în Adunarea Populară a Găgăuziei nu sunt persoane cu funcţii de demnitate publică nici în sensul Legii nr.199/2010, nici în sensul alin.(3 art.123 CP RM. Se ajunge la concluzia că, în rezultatul adoptării Legii nr.152/2016, definiţia noţiunii „persoană cu funcţie de demnitate publică” s-a transformat din definiţie exhaustivă în definiţie exemplificativă. Se argumentează că sintagma „altă persoană cu funcţie de demnitate publică stabilită prin lege” din alin.(3 art.123 CP RM arată că această normă constituie o normă divizată de referire. Se explică de ce este falsă impresia că ar exista persoane cu funcţie de demnitate publică, care nu sunt specificate în anexa la Legeanr.199/2010 şi cărora nu li se aplică prevederile acestei legi. Se conchide că alin.(3 art.123 CP RM, complinit de anexa la Legeanr.199/2010, sunt singurele norme care stabilesc conţinutul noţiunii „persoană cu funcţie de demnitate publică”. Alte norme pot doar să dezvolte prevederile acestora, fără a le lărgi sfera de incidenţă. Printre astfel de norme dezvoltătoare se numără: alin.(3 art.17 din Codul electoral; alin.(51 art.42 al Legii cu privire la energetică; art.131 al Legii privind Comisia Na

Effect of heat treatment on anodic activation of aluminium by trace element indium

Energy Technology Data Exchange (ETDEWEB)

Graver, Brit [Department of Materials Science and Engineering, Norwegian University of Science and Technology, N-7491 Trondheim (Norway); Helvoort, Antonius T.J. van [Department of Physics, Norwegian University of Science and Technology, N-7491 Trondheim (Norway); Nisancioglu, Kemal, E-mail: kemal.nisancioglu@material.ntnu.n [Department of Materials Science and Engineering, Norwegian University of Science and Technology, N-7491 Trondheim (Norway)

2010-11-15

Research highlights: {yields} Indium segregation activates AlIn alloy surface anodically in chloride solution. {yields} Enrichment of In on Al surface can occur thermally by heat treatment at 300 {sup o}C. {yields} Increasing temperature homogenises indium in aluminium reducing anodic activation. {yields} Indium can activate AlIn surface by segregating through dealloying of aluminium. {yields} Anodic activation is caused by AlIn amalgam formation at aluminium surface. - Abstract: The presence of trace elements in Group IIIA-VA is known to activate aluminium anodically in chloride environment. The purpose of this paper is to investigate the surface segregation of trace element In by heat treatment and resulting surface activation. Model binary AlIn alloys, containing 20 and 1000 ppm by weight of In, were characterized after heat treatment at various temperatures by use of glow discharge optical emission spectroscopy, electron microscopy and electrochemical polarization. Heat treatment for 1 h at 300 {sup o}C gave significant segregation of discrete In particles (thermal segregation), which activated the surface. Indium in solid solution with aluminium, obtained by 1 h heat treatment at 600 {sup o}C, also activated by surface segregation of In on alloy containing 1000 ppm In, resulting from the selective dissolution of the aluminium component during anodic oxidation (anodic segregation). The effect of anodic segregation was reduced by decreasing indium concentration in solid solution; it had negligible effect at the 20 ppm level. The segregated particles were thought to form a liquid phase alloy with aluminium during anodic polarization, which in turn, together with the chloride in the solution destabilized the oxide.

Sõprus äratab! : Ärkamised ja karjed kino Sõpruse ajaloos / Laura Talvet

Index Scriptorium Estoniae

Talvet, Laura

2010-01-01

Kinos Sõprus näidati 1990ndate alguses punkansamblist Sex Pistols' valminud dokumentaalfilmi "The Great Rock'N'Roll Swindle" (Suurbritannia 1980), režissöör Julien Temple. Artiklis tsiteeritakse Juq-Kalle Raidi, Kojamehe, Erik Morna ja Tõnu Trubetsky muljeid

Cultural Difference and Human Rights : A Philosophical-Anthropological Approach

NARCIS (Netherlands)

J. Kloeg (Julien)

2014-01-01

textabstractIn ‘Cultural Difference and Human Rights’, Julien Kloeg claims, with Pablo Gilabert, that theoretical attempts to justify human rights should move beyond the dichotomy of providing either a humanist or a political justification. Kloeg demonstrates how philosophical anthropology could

The logic of logistics: theory, algorithms and applications for logistics management

Directory of Open Access Journals (Sweden)

Claudio Barbieri da Cunha

2010-04-01

Full Text Available

Nesse texto o autor apresenta uma resenha acerca do livro "The logic of logistics: theory, algorithms and applications for logistics management", de autoria de Julien Bramel e David Simchi-Levi, publicado pela Springer-Verlag, em 1997.

La schizophrénie des théories éthiques contemporaines

Directory of Open Access Journals (Sweden)

Michael Stocker

2008-02-01

Full Text Available Parution originale sous le titre «The Schizophrenia of Modern Ethical Theories», _The Journal of Philosohy_, vol. 73, no 14, On Motives and Morals. (August 12, 1976, pp. 453-456. Traduit par Julien Corriveau, révisé par Christine Tappolet.

Le Cinematographe Ameerika kastmes / Tristan Priimägi

Index Scriptorium Estoniae

Priimägi, Tristan, 1976-

2007-01-01

French Connection : Prantsuse kino "The American Way" - Prantsuse filmikunsti suurteosed ja nende Ameerika uusversioonid kinos Sõprus 28. maist 1. juunini. Filmidest ja nende uusversioonidest : "Pepe le Moko" (Julien Duvivier, 1937) ja "Alžeerlased" (John Cromwell, 1938); "Metslane" (Jean Renoir, 1938) ja "Inimese iha" (Fritz Lang, 1938)

Ostrich: Journal of African Ornithology - Vol 86, No 1-2 (2015)

African Journals Online (AJOL)

Movement ecology of five Afrotropical waterfowl species from Malawi, Mali and Nigeria § · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. John Y Takekawa, Shane R Heath, Samuel A Iverson, Nicolas Gaidet, Julien Cappelle, Tim Dodman, Ward Hagemeijer, William D Eldridge, ...

Solid-state synthesis and characterization of LiCoO2 and LiNiyCo1 ...

Indian Academy of Sciences (India)

Unknown

than LiCoO2 and to possibly retain good lamellar struc- ture upon repeated cycling .... Julien C, Michael S S and Ziolkiewicz S 1999 Int. J. Inorg. Mater. 1 29. Kanno R, Kubo H, Kawamoto Y, Kamiyama T, Izumi F,. Takeda Y and Takano M 1994 ...

Young Artists@ CERN : 20 young artists from around Europe will travel to CERN for one week in January, 2004

CERN Multimedia

2004-01-01

From left to right, front row: Isambard Poulson, Floris van Heynsgergen, George Prassas, Andreas Mitropoulos, Andy Charalambous, organisateur and Nataly Sugnaux. Back row: Douglas Bourton, Denny Robson, Emma Hart, Eleanor Duffin, Caroline Gray, Grace Adam, Machyta Giebels, Janitsio Moreno Gomez, Paul Magee, Mark Ingham, Stine Ljungdalh and Julien Aubert.

The maternal genes Ci-p53/p73-a and Ci-p53/p73-b regulate zygotic ZicL expression and notochord differentiation in Ciona intestinalis embryos.

Science.gov (United States)

Noda, Takeshi

2011-12-01

I isolated a Ciona intestinalis homolog of p53, Ci-p53/p73-a, in a microarray screen of rapidly degraded maternal mRNA by comparing the transcriptomes of unfertilized eggs and 32-cell stage embryos. Higher expression of the gene in eggs and lower expression in later embryonic stages were confirmed by whole-mount in situ hybridization (WISH) and quantitative reverse transcription-PCR (qRT-PCR); expression was ubiquitous in eggs and early embryos. Knockdown of Ci-p53/p73-a by injection of antisense morpholino oligonucleotides (MOs) severely perturbed gastrulation cell movements and expression of notochord marker genes. A key regulator of notochord differentiation in Ciona embryos is Brachyury (Ci-Bra), which is directly activated by a zic-like gene (Ci-ZicL). The expression of Ci-ZicL and Ci-Bra in A-line notochord precursors was downregulated in Ci-p53/p73-a knockdown embryos. Maternal expression of Ci-p53/p73-b, a homolog of Ci-p53/p73-a, was also detected. In Ci-p53/p73-b knockdown embryos, gastrulation cell movements, expression of Ci-ZicL and Ci-Bra in A-line notochord precursors, and expression of notochord marker gene at later stages were perturbed. The upstream region of Ci-ZicL contains putative p53-binding sites. Cis-regulatory analysis of Ci-ZicL showed that these sites are involved in expression of Ci-ZicL in A-line notochord precursors at the 32-cell and early gastrula stages. These results suggest that p53 genes are maternal factors that play a crucial role in A-line notochord differentiation in C. intestinalis embryos by regulating Ci-ZicL expression. Copyright © 2011 Elsevier Inc. All rights reserved.

Estimation of pulses in ultrasound B-scan images

DEFF Research Database (Denmark)

Jensen, Jørgen Arendt

1991-01-01

It is shown, based on an expression for the received pressure field in pulsed medical ultrasound systems, that a common one-dimensional pulse can be estimated from individual A-lines. An autoregressive moving average (ARMA) model is suggested for the pulse, and an estimator based on the prediction...... error method is derived. The estimator is used on a segment of an A-line, assuming that the pulse does not change significantly inside the segment. Several examples of the use of the estimator on synthetic data measured from a tissue phantom and in vitro data measured from a calf's liver are given....... They show that a pulse can be estimated even at moderate signal-to-noise ratios...

OSATE Overview & Community Updates

Science.gov (United States)

2015-02-15

update 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Delange /Julien 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK...main language capabilities Modeling patterns & model samples for beginners Error-Model examples EMV2 model constructs Demonstration of tools Case

PROTECŢIA PENALĂ A PATRIMONIULUI CULTURAL DIN PERSPECTIVA AMENDAMENTELOR OPERATE PRIN LEGEA NR.75/2016

Directory of Open Access Journals (Sweden)

Sergiu BRÎNZA

2016-11-01

Full Text Available În cadrul studiului sunt supuse interpretării prevederile normative introduse în Codul penal prin Legea nr.75/2016.În contextul interpretării alin.(21 art.186, alin.(21 art.187, alin.(21 art.188, alin.(21 art.190 şi alin.(22 art.191 CP RM,este stabilit conţinutul noţiunilor „bunuri de patrimoniu cultural”, „situri arheologice” şi „zone cu potenţial arheologic”.Se argumentează că infracţiunile prevăzute la art.1991 CP RM pot fi comise cu intenţie sau din imprudenţă. În vedereainterpretării dispoziţiilor art.1992 CP RM, este identificat semantismul noţiunilor „săpături neautorizate”, „comori”,„lucrări de construcţie”, „alte activităţi de intervenţie asupra solului” şi „certificat de descărcare de sarcină arheologică”.De asemenea, este stabilit criteriul de distincţie între tăinuirea sau păstrarea ilegală a bunurilor arheologice mobile (însensul art.1993 CP RM şi sustragerea aceloraşi bunuri (în sensul alin.(21 art.186, alin.(21 art.187, alin.(21 art.188,alin.(21 art.190 şi alin.(22 art.191 CP RM. Se demonstrează că administratorul terenului, în care s-a făcut descoperireaarheologică întâmplătoare, şi/sau reprezentantul responsabil al autorităţii administraţiei publice sunt cei care omit să anunţela timp autorităţile publice cu privire la descoperirea întâmplătoare a bunurilor arheologice mobile (inclusiv a comorilor.Nu în ultimul rând, se relevă că, în toate cazurile, monumentele de for public posedă calitatea de monumente care fac partedin patrimoniul cultural în sensul lit.a alin.(3 art.1 al Legii privind ocrotirea monumentelor. Utilizând în art.222 CP RMnoţiunea „monument de for public”, legiuitorul a luat implicit în considerare faptul că un asemenea monument este un bunaparţinând patrimoniului cultural naţional mobil. Cât priveşte monumentul funerar, şi acesta poate cumula calitatea demonument care face parte din patrimoniul

Culturalisme et réflexion existentialiste— Une lecture de Retour de ...

African Journals Online (AJOL)

Published in 2008, the novel Retour de manivelle by Julien Kilanga Musinde revives the unfinished debate related to the search of identity in African writing. ... the paper is aimed at demonstrating, however, that the culture that is depicted as both exclusive and dynamic in Musinde's work should be understood mainly in ...

Explosion and fire in the uranium trioxide production facilities at the Savannah River Plant on February 12, 1975. A works technical report

International Nuclear Information System (INIS)

McKibben, J.M.

1976-10-01

On February 12, 1975, an explosion and fire occurred in the denitrator room of the separations A-Line facility, resulting in minor injury to two employees and about $230,000 damage to the building and equipment. The facility, which converts uranyl nitrate solution to UO 3 , had operated for 20 years without major accident. Accidental transfer of tributyl phosphate--uranyl nitrate adduct into a denitrator was followed by rapid decomposition of the organic material. Combustible gases were released into the denitrator room and ignited. No contamination was spread outside the facility. A-Line returned to operation August 11, 1975, after equipment and procedures were modified to lower the probability of similar incidents to a very low level. 18 figures, 9 tables

Lois : J.O n° 55 du 6 mars 2007 page 4206, texte n° 5

Directory of Open Access Journals (Sweden)

2009-12-01

Full Text Available LOI n° 2007-291 du 5 mars 2007 tendant à renforcer l’équilibre de la procédure pénale (1NOR: JUSX0600156LL’Assemblée nationale et le Sénat ont adopté, Le Président de la République promulgue la loi dont la teneur suit :Chapitre IerDispositions instaurant la collégialité de l’instructionArticle 1Le premier alinéa de l’article 83 du code de procédure pénale est remplacé par deux alinéas ainsi rédigés : « Le président du tribunal ou, en cas d’empêchement, le magistrat qui le remplace, désigne, ...

Poeetilised prantslased / Kristiina Davidjants

Index Scriptorium Estoniae

Davidjants, Kristiina, 1974-

2007-01-01

French Connection : Prantsuse kino "The American Way" - Prantsuse filmikunsti suurteosed ja nende Ameerika uusversioonid kinos Sõprus 28. maist 1. juunini. Lähemalt filmidest "Pepe le Moko" (Julien Duvivier, 1937), "Metslane" (Jean Renoir, 1938), "Viimasel hingetõmbel" (Jean-Luc Godard, 1959), "Uppumissurmast päästetud Boudu" (Jean Renoir, 1932), "Naine nimega Nikita" (Luc Besson, 1990)

Forklift Champions

CERN Multimedia

2005-01-01

A team of CERN forklift truck operators has come runner-up in the 2005 French Championships. It is an achievement which has put this professional activity, which plays an essential role at CERN, into the spotlight. The team, sporting CERN team colours, at the French Forklift Championships. From left to right: Jose Pereira Lages, Johann Dhote, Julien Fermanel and Franck Stach. There was never any doubt that CERN played host to the cream of the physics world, top-class engineers and computing experts. However, excellence is to be found in all professional fields. Thus, a team of three handling and transport experts from CERN came runner-up in the French Forklift Championships, which took place in Lyon on 5 October. The three CERN participants from the TS/IC Group's Logistics Section, Jose Pereira Lages (Leader of the LHC General Services Team at Points 1 and 8), Johann Dhote (Leader of the Team responsible for lowering the magnets at Point SMI2) and Julien Fermanel (a member of the General Services transpo...

Next step, the Tour de France?

CERN Multimedia

Anaïs Schaeffer

2013-01-01

The penultimate stage of the 2013 Tour de France, the Annecy-Semnoz time-trial, has already been won – by a CERN staff member!     In keeping with tradition, the organisers of the Tour de France organise another race, the Étape du Tour, which is open to the general public and follows the actual route of an official stage of the Tour proper. This year, the chosen venue was Annecy and its neighbouring mountain, Le Semnoz, which played host to 11,000 cycling enthusiasts from all parts. This penultimate stage of the 2013 Tour will be raced by the professionals on 20 July. The public race was won by Nicolas Roux, an experienced cyclist and member of CERN’s GS-IS Group, who devoured the 128-km course in just 4 hours and 15 minutes, nine seconds ahead of cycling champion Julien Absalon. “I just managed to overhaul Julien Absalon 500 m before the finishing line,” Nicolas recounts. “It was a fantastic race!” Come rain o...

The effect of transverse bed slope and sediment mobility on bend sorting

NARCIS (Netherlands)

Weisscher, S.A.H.; Baar, A.W.; Uijttewaal, W.S.J.; Kleinhans, MG

2017-01-01

Lateral sorting (= bend sorting) is observed in  natural meanders, where the inner and outer  bend are fairly fine and coarse, respectively  (e.g. Julien and Anthony, 2002; Clayton and  Pitlick, 2007). This is caused by the mass  differences between grains on a

L'art et la guérison—Des impératifs éthiques dans Jardin secret de ...

African Journals Online (AJOL)

This article sets out to analyse a trend in literary (re)positioning in the context of socio-political confrontation. In keeping with the literary approach adopted by Julien Kilanga Musinde in the novel Jardin secret (2010), the article will focus on defining the ultimate objective (s) of literary writing in a context where the novel genre ...

Proteomic analysis reveals strong mitochondrial involvement in cytoplasmic male sterility of pepper (Capsicum annuum L.).

Science.gov (United States)

Guo, Jinju; Wang, Peng; Cheng, Qing; Sun, Limin; Wang, Hongyu; Wang, Yutong; Kao, Lina; Li, Yanan; Qiu, Tuoyu; Yang, Wencai; Shen, Huolin

2017-09-25

Although cytoplasmic male sterility (CMS) is widely used for developing pepper hybrids, its molecular mechanism remains unclear. In this study, we used a high-throughput proteomics method called label-free to compare protein abundance across a pepper CMS line (A-line) and its isogenic maintainer line (B-line). Data are available via ProteomeXchange with identifier PXD006104. Approximately 324 differentially abundant protein species were identified and quantified; among which, 47 were up-accumulated and 140 were down-accumulated in the A-line; additionally, 75 and 62 protein species were specifically accumulated in the A-line and B-line, respectively. Protein species involved in pollen exine formation, pyruvate metabolic processes, the tricarboxylic acid cycle, the mitochondrial electron transport chain, and oxidative stress response were observed to be differentially accumulated between A-line and B-line, suggesting their potential roles in the regulation of pepper pollen abortion. Based on our data, we proposed a potential regulatory network for pepper CMS that unifies these processes. Artificial emasculation is a major obstacle in pepper hybrid breeding for its high labor cost and poor seed purity. While the use of cytoplasmic male sterility (CMS) in hybrid system is seriously frustrated because a long time is needed to cultivate male sterility line and its isogenic restore line. Transgenic technology is an effective and rapid method to obtain male sterility lines and its widely application has very important significance in speeding up breeding process in pepper. Although numerous studies have been conducted to select the genes related to male sterility, the molecular mechanism of cytoplasmic male sterility in pepper remains unknown. In this study, we used the high-throughput proteomic method called "label-free", coupled with liquid chromatography-quadrupole mass spectrometry (LC-MS/MS), to perform a novel comparison of expression profiles in a CMS pepper line

Séminaire de physique corpusculaire | 19 December

CERN Multimedia

2012-01-01

Active and Sterile Neutrinos in Cosmology by Prof. Julien Lesgourges, EPFL (Lausanne) Wednesday 19 December 2012 at 11:15 Science III, Auditoire 1S081 30, quai Ernest-Ansermet, 1211 Genève 4 Abstract: Review of status and prospects for constraining the neutrino sector using cosmological observables, with an emphasis on cosmic microwave background and large scale structure data. More information here.

Gridded Surface Subsurface Hydrologic Analysis (GSSHA) User’s Manual; Version 1.43 for Watershed Modeling System 6.1

Science.gov (United States)

2006-09-01

name Name of GRASS ASCII map containing spatially-distributed values of the Uni- versal Soil Loss Equation ( USLE ) soil erodability index (0.0 – 1.0...as modified by Julien (1995) is a highly empirical formulation. The soil , cropping, and land use factors (K, C, and P) from the USLE are not related...28 ERDC/CHL SR-06-1 iv Soil Erosion - Optional

H-NMR metabolomics: Profiling method for a rapid and efficient ...

African Journals Online (AJOL)

user

2012-06-28

Jun 28, 2012 ... Yosra Ben Akal-Ben Fatma1, Katia Pianelli2, Martine Dieuaide-Noubhani3, Aline Le Menn5,. Catherine ... science (Sobolev et al., 2003), nutrition and quality (Hall ...... the leaves of C3 plants also showed an increase of.

Travel Support for Scientists to Participate in ACS Symposium

Science.gov (United States)

2017-08-31

ESPCI- Paris , France) at the 252nd ACS National Meeting in Philadelphia, Aug 21-25, 2016. In this two-day event, we have 30 oral presentations (17...Scott Grayson (Tulane University), Prof. Jemeriah Johnson (MIT), Prof. Julien Nicolas (Université Paris -Sud). Training Opportunities: Among the 30...polymer catalysts, to self-healing materials and pollution salvation materials. On this aspect, both academia and industrial laboratories have reached

A Requirement Specification Language for AADL

Science.gov (United States)

2016-06-01

models. The objective of ReqSpec is to support the elicitation , definition, and modeling of requirements for real-time embedded systems in an iterative...A Requirement Specification Language for AADL Peter H. Feiler Julien Delange Lutz Wrage June 2016 TECHNICAL REPORT CMU/SEI-2016-TR-008...is required for any other external and/or commercial use. Requests for permission should be directed to the Software En- gineering Institute at

Mari Laaniste soovitab : "Rock on Screen" / Mari Laaniste

Index Scriptorium Estoniae

Laaniste, Mari, 1977-

2008-01-01

5.-11. juulini Tallinnas kinos Sõprus toimuvast muusikafilmide nädalast "Rock on Screen". Programmis on Julian Schnabeli kontsertfilm "Lou Reed's Berlin" (2007), Julien Temple'i "Tulevik on veel kirjutamata" (2007, pühendatud Joe Strummeri mälestusele), Anton Corbijni draama "Control" Joy Divisoni liidrist Ian Curtisest, JP Siili mängufilm "Hurriganes" (2007, soome rockansamblist) ja Peeter Urbla muusikafilm "Shlaager" (1983, filmi kangelannat kehastab Els Himma)

Pernilla Craig Flight Around Lac Leman

CERN Multimedia

Goldfarb, Steven

2013-01-01

Aviator and future physicist Pernilla Craig visits CERN and is hosted by the Geneva Flight Club. Web pioneer Robert Cailliau helps in the preparations, flight instructor Aline Cosmetatos takes the co-pilot seat, and ATLAS outreach coordinator Steven Goldfarb serves cocktails from the back seat.

Behavior of tributyl phosphate in A-line processes

International Nuclear Information System (INIS)

Harmon, H.D.; Hyder, M.L.; Tiffany, B.; Gray, L.W.; Soltys, P.A.

1976-08-01

The chemical and physical properties of uranyl nitrate--tributyl phosphate adduct (UO 2 ) (NO 3 ) 2 (TBP) 2 were studied to define optimum, safe operating conditions for denitration of uranyl nitrate (UN) solutions containing low concentrations of adduct. The distribution of TBP between aqueous UN solutions and organic phases (TBP pure or diluted in n-paraffin) was measured. Specific gravity measurements confirmed published data for aqueous UN solutions, but disagreed with literature data for 100 percent TBP. Intersection of the UN specific gravity curve and the 100 percent TBP data of this work indicated that phase inversion cannot occur when the aqueous phase contains greater than or equal to 330 g U/1. Thermal decomposition of adduct occurs in one gradual weight loss step below 170 0 C and in two successive steps above 170 0 C. Rate constants for the first reaction were calculated for 130 to 210 0 C. The major flammable decomposition product was l-butene; inorganic gases formed were N 2 , NO, N 2 O, CO, and CO 2 . Adduct decomposition during denitration of UN was characterized by foaming and by gas evolution (mostly nonflammable) at 135 to 185 0 C. Maximum flammable gas evolution and potential self-heating by TBP oxidation were calculated

The LHC goes in for an X-ray

CERN Multimedia

Anaïs Vernède

2011-01-01

For the past two years, a radiography laboratory has been operating in a "bunker" where it can X-ray materials in complete safety. The primary function of the radiography laboratory, run by Jean-Michel Dalin and Aline Piguiet, is to inspect welds and LHC components.   Technicians Jean-Michel Dalin and Aline Piguiet, from the EN department,  with the scanner used for digital radiography. In the basement of Building 112 lies a bunker heavily protected against radiation leaks and housing a laboratory that employs high-tech apparatus capable of detecting the slightest fault in materials without destroying or damaging them. "It's the principle of Non-Destructive Testing (NDT). In our laboratory we essentially use two methods, tomography and digital radiography," explains Jean-Michel Dalin, who is a NDT radiography technician in the EN Department's MM Section. It was he who designed the laboratory in collaboration with CERN's radiation protection service, wh...

Avoiding Praetorian Societies: Focusing U.S. Strategy on Political Development

Science.gov (United States)

2014-03-01

equivalent to Malcolm 51 Gladwell’s connectors, people who build wide net- works of acquaintances so they can make opportunity linkages when needed.90...Local Structure in Afghanistan? And What is IDLG?” Presentation at the COIN Academy, Camp Julien, Af- ghanistan, 3 March 2010, slides 6-11. 90. Malcolm ... Gladwell , The Tipping Point: How Little Things Can Make a Big Difference, New York, NY: Little Brown and Com- pany, 2000, p. 38. 91. Stephen

Ian Curtis (2001)

OpenAIRE

Dalwood, D

2016-01-01

This exhibition offers a presentation of FRAC Champagne-Ardenne‘s collection; artists included: Francesco Arena, Sylvie Auvray, Dara Birnbaum, Rossella Biscotti, Tom Burr, Antoine Catala, Guy de Cointet, Ann Craven, Dexter Dalwood, Hassan Darsi, Plamen Dejanoff, Marcelline Delbecq, Julien Discrit, Jimmie Durham, Ruth Ewan, Michel François, Linda Fregni Nagler, Aurélien Froment, General Idea, Oscar Giaconia, Jean-Michel Hannecart, Sharon Hayes, Charline von Heyl, Barbara Kasten, Nick Mauss, Ma...

Brüssel Euroopa pealinnaks? / Ülar Mark

Index Scriptorium Estoniae

Mark, Ülar, 1968-

2009-01-01

Brüsseli Euroopa kvartali planeerimisvõistlusest, mille peakorraldaja oli Brüsseli pealinna piirkond koos Brüsseli linna ja Euroopa Komisjoniga. Eestist osales žüriis arhitekt Ülar Mark. Meeskonna Atelier Christian de Portzamparc võidutööst ja teiste teise vooru pääsenud nelja meeskonna (JDS / Julien De Smedt Architects, OMA / Office for Metropolitan Architecture, Xaveer De Geyter Architect, Fletcher Priest Architects) töödest

New composite index based on midlatency auditory evoked potential and electroencephalographic parameters to optimize correlation with propofol effect site concentration - Comparison with bispectral index and solitary used fast extracting auditory evoked potential index

NARCIS (Netherlands)

Vereecke, HEM; Vasquez, PM; Jensen, EW; Thas, O; Vandenbroecke, R; Mortier, EP; Struys, MMRF

Background: This study investigates the accuracy of a composite index, the A-Line (R) auditory evoked potentials index version 1.6 (AAI(1.6); Danmeter A/S, Odense, Denmark), as a measure of cerebral anesthetic drug effect in a model for predicting a calculated effect site concentration of propofol

Detection probabilities for time-domain velocity estimation

DEFF Research Database (Denmark)

Jensen, Jørgen Arendt

1991-01-01

programs, it is demonstrated that the probability of correct estimation depends on the signal-to-noise ratio, transducer bandwidth, number of A-lines and number of samples used in the correlation estimate. The influence of applying a stationary echo-canceler is explained. The echo canceling can be modeled...

Retinal nerve fiber layer thickness map determined from optical coherence tomography images

NARCIS (Netherlands)

Mujat, M.; Chan, R. C.; Cense, B.; Park, B.H.; Joo, C.; Akkin, T.; Chen, TC; de Boer, JF

2005-01-01

We introduce a method to determine the retinal nerve fiber layer (RNFL) thickness in OCT images based on anisotropic noise suppression and deformable splines. Spectral-Domain Optical Coherence Tomography (SDOCT) data was acquired at 29 kHz A-line rate with a depth resolution of 2.6 mum and a depth

William Shakespeare’ın Hamlet Yapıtının A. J. Greimas’ın Eyleyensel Örnekçesine Göre Çözümlenmesi

OpenAIRE

Baloğlu, Uğur

2013-01-01

The analysis of semiology has been previously used in only linguistic analysis but in time it was started to be used to analyse in different ares such as cinema, music, advertising poster etc. In this article, Algirdas Julien Greimas’s the actantial model and narrative curriculum will be discussed who was inspired by narrative science of Vladimir Propp in respect to the structuralism and making up his own analysis method. Considering these facts, William Shakespeare’s play...

Wild Vegetables, Salsa, and Street Art. Cultural and Ecological Developments in the Chinese Provincial Landscape

Directory of Open Access Journals (Sweden)

Andrea Baldini

2016-09-01

Full Text Available A young boy and girl are sitting in front of one another, seemingly looking at each other. They are separated by a small dam. These are not real persons, but elements of a mural by French street artist Seth, whose real name is Julien Malland. Seth painted this work in June 2015, using the walls of a building in the Jinshan District, a suburban area in the countryside around Shanghai, as his canvas.

Causes and consequences of obesity: epigenetics or hypokinesis?

OpenAIRE

Graham, Michael R; Baker, Julien S; Davies, Bruce

2015-01-01

Michael R Graham,1 Julien S Baker,2 Bruce Davies3 1Llantarnam Research Academy, Cwmbran, Torfaen, UK; 2Exercise Science Research Laboratory, Institute of Clinical Exercise and Health Science, School of Science, University of the West of Scotland, Hamilton, UK; 3Science Department, University of South Wales, Newport, UKEpigenetics can be defined as the study of heritable changes that affect gene function without modification of the deoxyribonucleic acid (DNA) sequence.1 The transfer of epigene...

ELEMENTELE CONSTITUTIVE ŞI ELEMENTELE CIRCUMSTANŢIALE AGRAVANTE ALE INFRACŢIUNILOR CONTRA PATRIMONIULUI MILITAR

Directory of Open Access Journals (Sweden)

Sergiu BRÎNZA

2016-11-01

Full Text Available Articolul de faţă este dedicat analizei juridico-penale a infracţiunilor contra patrimoniului militar, prevăzute laart.379-381 CP RM. Sunt examinate elementele constitutive (obiectul, latura obiectivă, latura subiectivă şi subiectul,precum şi elementele circumstanţiale agravante ale acestor infracţiuni. Sunt propuse criterii de delimitare a infracţiunilorspecificate la art.379-381 CP RM în raport cu faptele conexe de factură penală sau nepenală. Printre aspectele de noutateale studiului de faţă trebuie remarcată revizuirea concepţiei de identificare a variantelor-tip şi a variantelor agravate în cazulinfracţiunilor prevăzute la art.379 CP RM. În rezultatul analizei efectuate se ajunge la concluzia că, datorită specificului lor,infracţiunile contra patrimoniului militar nu au victimă. De asemenea, se stabileşte că infracţiunile prevăzute la art.379-381CP RM sunt săvârşite pe calea acţiunii (şi sau inacţiunii. Se arată că, de cele mai dese ori, infracţiunile contra patrimoniului militar au o factură materială. Doar în situaţia infracţiunii prevăzute la alin.(1 art.381 CP RM se atestă existenţa semnelor atât ale unei infracţiuni materiale, cât şi ale unei infracţiuni formale. Se relevă că timpul de război este un semn secundarobligatoriu al laturii obiective în ipoteza infracţiunilor specificate la lit.a alin.(3 art.379, lit.a alin.(2 art.380, lit.a alin.(2şi lit.a alin.(4 art.381 CP RM. Se stabileşte că ambianţa infracţiunii (şi anume – condiţiile de luptă constituie un semnsecundar obligatoriu al laturii obiective în cazul infracţiunilor prevăzute la lit.b alin.(3 art.379, lit.b alin.(2 art.380, lit.balin.(2 şi lit.b alin.(4 art.381 CP RM. Se arată că infracţiunea specificată la art.380 CP RM este săvârşită din imprudenţă.În situaţii de altă natură, făptuitorul manifestă intenţie sau imprudenţă faţă de fapta prejudiciabilă şi numai impruden

Models of the Human in Tantric Hinduism

DEFF Research Database (Denmark)

Olesen, Bjarne Wernicke; Flood, Gavin

2019-01-01

This research project explores the origins, developments and transformations of yogic models of the human (e.g. kuṇḍalinī yoga, the cakra system and ritual sex) in the tantric goddess traditions or what might be called Śāktism of medieval India. These Śākta models of esoteric anatomy originating...

RNA Regulation of Estrogen

Science.gov (United States)

2010-08-01

Berglund, Rodger Voelker, Paul Barber and Julien Diegel 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING...estrogen  receptors  [reviewed  in  (3,  4)],  also   functions   by  interacting  directly  with  RNA  to  alter  RNA...Mog myelin oligodendrocyte glycoprotein 6.06 207115_x_at mbtd1 mbt domain containing 1 6.06 208004_at Prol1 proline rich, lacrimal 1 6.06 205247_at

Pluriannual variability of sedimentation on mudflats in a macrotidal estuary

Science.gov (United States)

Cuvilliez, A.; Lafite, R.; Deloffre, J.; Massei, N.; Langlois, E.; Sakho, I.

2010-12-01

Antoine Cuvilliez1, Robert Lafite2, Julien Deloffre2, Nicolas Massei2, Estelle Langlois 3 and Issa Sakho2 1 Université du Havre, FRE 3102, Laboratoire d’ondes et milieux complexes, Université du Havre, 76058 Le Havre cedex, France 2 Université de Rouen, UMR 6143, Morphodynamique Continentale et Côtière, 76821 Mont Saint Aignan Cedex, France. 3 Université de Rouen, ECODIV , Etude et Compréhension de la Biodiversité, 76821 Mont Saint Aignan Cedex, France.

Oblique Orientation Discrimination Thresholds Are Superior in Those with a High Level of Autistic Traits

Science.gov (United States)

Dickinson, Abigail; Jones, Myles; Milne, Elizabeth

2014-01-01

Enhanced low-level perception, although present in individuals with autism, is not seen in individuals with high, but non-clinical, levels of autistic traits (Brock et al.in "Percept Lond" 40(6):739. doi:10.1068/p6953, 2011). This is surprising, as many of the higher-level visual differences found in autism have been shown to correlate…

Seks ja töö / Andres Maimik

Index Scriptorium Estoniae

Maimik, Andres, 1970-

2000-01-01

Filmifestivalil "Armastus ja Anarhia" ("Rakkautta & Anarkiaa") 21.09.- 01.10. nähtud filmidest : Rosa von Praudheimi eluloofilm "Einstein of Sex", Julien Temple dokumentaalfilm "The Filth and the Fury", Virginie Despentes ja Coralie Trinh Thi "Baise moi!" ("Vägista mind!"), Catherine Breillat "Une vraie Jeune Fille" ("Päris noor tüdruk"), Francois Ozoni Rainer Werner Fassbinderi näidendi järgi tehtud film "Gouttes d'eau sur pierres brulantes" ("Veetilgad põlevatel kividel"), Jang Sun Woo "Gojimal" ("Valed") ja Laurent Cantet' "Ressources humaines" ("Inimressursid")

The Decade of Education for Sustainable Development: Towards four pillars of learning

OpenAIRE

Shivali Lawale; Aline Bory-Adams

2010-01-01

Education for sustainable development is a paradigm shift in education which goes beyond the traditional realms of education. Shivali Lawale and Aline Bory-Adams assess how education for sustainable development could build sustainable societies through the Decade of Education for sustainable development. They explore how to build a conceptual framework based on the four pillars of learning proposed by the Delors Report.

Understanding Climate Uncertainty with an Ocean Focus

Science.gov (United States)

Tokmakian, R. T.

2009-12-01

Uncertainty in climate simulations arises from various aspects of the end-to-end process of modeling the Earth’s climate. First, there is uncertainty from the structure of the climate model components (e.g. ocean/ice/atmosphere). Even the most complex models are deficient, not only in the complexity of the processes they represent, but in which processes are included in a particular model. Next, uncertainties arise from the inherent error in the initial and boundary conditions of a simulation. Initial conditions are the state of the weather or climate at the beginning of the simulation and other such things, and typically come from observations. Finally, there is the uncertainty associated with the values of parameters in the model. These parameters may represent physical constants or effects, such as ocean mixing, or non-physical aspects of modeling and computation. The uncertainty in these input parameters propagates through the non-linear model to give uncertainty in the outputs. The models in 2020 will no doubt be better than today’s models, but they will still be imperfect, and development of uncertainty analysis technology is a critical aspect of understanding model realism and prediction capability. Smith [2002] and Cox and Stephenson [2007] discuss the need for methods to quantify the uncertainties within complicated systems so that limitations or weaknesses of the climate model can be understood. In making climate predictions, we need to have available both the most reliable model or simulation and a methods to quantify the reliability of a simulation. If quantitative uncertainty questions of the internal model dynamics are to be answered with complex simulations such as AOGCMs, then the only known path forward is based on model ensembles that characterize behavior with alternative parameter settings [e.g. Rougier, 2007]. The relevance and feasibility of using "Statistical Analysis of Computer Code Output" (SACCO) methods for examining uncertainty in

Contribuciones hacia la cronología del Periodo Arcaico en las punas de Junín

OpenAIRE

Kaulicke, Peter

2012-01-01

Some Contributions to the Chronology of the Archaic Period in the Punas of JunínThe stratigraphy and the typology from the Uchkumachay excavations are presented as well as preliminary results of a comparative study undertaken in collaboration with D. Lavallée and M. Julien. These data bear major importance on the building of a general chronology and synthesis of the Archaic Period which still is missing for the Junín area in spite of being one of the best studied areas in the Central Andes fo...

RNA Regulation by Estrogen

Science.gov (United States)

2011-08-01

Julien Diegel, Amy Mahady, and Micah Bodner 5e. TASK NUMBER E-Mail: aberglund@molbio.uoregon.edu 5f. WORK UNIT NUMBER 7. PERFORMING...4)],  also   functions   by  interacting  directly  with  RNA  to  alter  RNA  processing  events  such  as  splicing...1 6.06 208004_at Prol1 proline rich, lacrimal 1 6.06 205247_at NOTCH4 Notch homolog 4 (Drosophila) 6.06 211203_s_at Cntn1 contactin 1 6.06 220689_at

Brianchón y su Teorema

Directory of Open Access Journals (Sweden)

José Manuel Sánchez Muñoz

2011-05-01

Full Text Available Este artículo versa sobre las investigaciones de un joven Charles Julien Brianchón cuando sólo contaba con 21 años y estaba aún en su época de estudiante del École Polytechnique de París. Estos resultados sirvieron para poner de manifiesto uno de los pilares fundamentales de la cada vez más importante Geometría Proyectiva, el Principio de Dualidad y su relación con el Teorema de Pascal sobre cónicas demostrado 167 años antes.

Modelo actancial. Los resortes narratológicos de la obra de Greimas

OpenAIRE

David Cruz, Janeth

2013-01-01

Este texto parte de una investigación sobre la configuración del relato en el cine de animación de la alianza Disney - Pixar y estudia el concepto del personaje desde la perspectiva del modelo actancial. Dicho modelo ha sido teorizado por Algirdas Julien Greimas y se basa en la idea de entender el personaje como un actante, es decir como un vehículo que permite el desarrollo de las acciones narrativas. Por eso se explica el alcance del modelo, sus orígenes y las actualizaciones y reinterpreta...

High Performance JavaScript

CERN Document Server

Zakas, Nicholas

2010-01-01

If you're like most developers, you rely heavily on JavaScript to build interactive and quick-responding web applications. The problem is that all of those lines of JavaScript code can slow down your apps. This book reveals techniques and strategies to help you eliminate performance bottlenecks during development. You'll learn how to improve execution time, downloading, interaction with the DOM, page life cycle, and more. Yahoo! frontend engineer Nicholas C. Zakas and five other JavaScript experts -- Ross Harmes, Julien Lecomte, Steven Levithan, Stoyan Stefanov, and Matt Sweeney -- demonstra

The Effects of Chloroquine-Resistant and Chloroquine-Sensitive Strains of Berghei on Rodent Hepatic Drug-Metabolizing Enzymes

Science.gov (United States)

1993-10-14

fascioliasis and visceral leishmaniasis (Tekwani et al., 1988; Cha and Edwards, 1976: Hosts showed reduction of reductase. Facino et al...in bovine fascioliasis . Toxicology Letters 159 20,231-236. Feyereisen , R., J. F. Koener, D. E. Farnsworth, and D. W. Nebert. 1989. Isolation and...More, and M. France . 1983 . Impairment of drug metabolism by the liver in experimental fascioliasis in the rat . Journal of Pharmacy and

Conformational preferences of DNA following damage by aristolochic acids: Structural and energetic insights into the different mutagenic potential of the ALI and ALII-N(6)-dA adducts.

Science.gov (United States)

Kathuria, Preetleen; Sharma, Purshotam; Abendong, Minette N; Wetmore, Stacey D

2015-04-21

Aristolochic acids (AAI and AAII), produced by the Aristolochiaceae family of plants, are classified as group I (human) carcinogens by the International Agency for Research on Cancer. These acids are metabolized in cells to yield aristolactams (ALI and ALII, respectively), which further form bulky adducts with the purine nucleobases. Specifically, the adenine lesions are more persistent in cells and have been associated with chronic renal diseases and related carcinogenesis. To understand the structural basis of the nephrotoxicity induced by AAs, the ALI-N(6)-dA and ALII-N(6)-dA lesions are systematically studied using computational methods. Density functional theory calculations indicate that the aristolactam moiety intrinsically prefers a planar conformation with respect to adenine. Nucleoside and nucleotide models suggest that the anti and syn orientations about the glycosidic bond are isoenergetic for both adducts. Molecular dynamics simulations and free energy calculations reveal that the anti base-displaced intercalated conformation is the most stable conformer for both types of AL-N(6)-dA adducted DNA, which agrees with previous experimental work on the ALII-N(6)-dA adduct and thereby validates our approach. Interestingly, this conformer differs from the dominant conformations adopted by other N6-linked adenine lesions, including those derived from polycyclic aromatic hydrocarbons. Furthermore, the second most stable syn base-displaced intercalated conformation lies closer in energy to the anti base-displaced intercalated conformation for ALI-N(6)-dA compared to ALII-N(6)-dA. This indicates that a mixture of conformations may be detectable for ALI-N(6)-dA in DNA. If this enhanced conformational flexibility of double-stranded DNA persists when bound to a lesion-bypass polymerase, this provides a possible structural explanation for the previously observed greater nephrotoxic potential for the ALI versus ALII-N(6)-dA adduct. In addition, the structural

DILEMA DIFERENŢIERII RĂSPUNDERII PENALE PENTRU RELELE TRATAMENTE COMISE DE O PERSOANĂ CU FUNCŢIE DE RĂSPUNDERE

Directory of Open Access Journals (Sweden)

Daniela URSU

2017-01-01

Full Text Available Deoarece unele autorităţi (ca, de exemplu, poliţistul sunt, potrivit literei legii (art.123 alin.(1 şi alin.(2 CP RM, atât persoane publice, cât şi persoane cu funcţie de răspundere, în contextul relelor tratamente incriminate la art.1661 CP RM, unii subiecţi de aplicare în concret a legii penale recunosc poliţistului calitatea de persoană cu funcţie de răspundere, motiv din care reţin circumstanţa agravantă în dependenţă de faptă, prevăzută fie la lit.e alin.(2, fie la lit.e alin.(4 art.1661 CP RM, iar alţii îi reţin calitatea de persoană publică, încadrându-i faptele în acord cu variantele-tip ale infrac­ţiu­nilor de tortură, tratament inuman sau degradant. Pornind de la câteva hotărâri din practica judiciară naţională, pre­zentul studiu îşi propune să ofere răspuns la următoarea întrebare: Care este cea mai potrivită soluţie de calificare în ipo­teza comiterii infracţiunilor de tortură, tratament inuman sau degradant de către autorităţi care deţin dubla calitate: atât de persoană publică, cât şi de persoană cu funcţie de răspundere?THE DIFFERENTIATION DILEMMA OF CRIMINAL LIABILITY REGARDING THE ILL-TREATMENT COMMITTED BY A PERSON WITH PUBLIC RESPONSIBILITIESBecause some authorities, like the policeman, are according to the law (Article 123 para.(1 and para.(2 of the Penal Code of Moldova, both public persons and persons holding responsible positions, in the context of maltreatment incri­minated by the article 1661 of the Penal Code of Moldova, some subjects invested with the power to apply the criminal law treat the police officials as persons holding a responsible positions, the reason why the aggravating circumstance, depending on the offense, is either letter e para.(2, either – letter e para.(4 article 1661 of the Penal Code of Moldova. While others treat them as public persons, stating their crimes as torture, inhuman or degrading treatment. Starting from several

Seismic Response to Sonic Boom-Coupled Rayleigh Waves

Science.gov (United States)

1990-06-28

side slopes and moderately deep well-drained, gently sloping to moderately steep soils on terraces; Ann. Rainfall--10" to 16") Cath-Timpahute- Jarab ...slopes less than 15%, and Alluvial land) Jarab Series (cobbley loam, gravelly loam, gravelly clay loam, pan fragments, hardpan with silica laminae...weakly and strongly cemented with lime, soft, calcareous gravelly loam: al!-aline, calcareous) Jarab cobbley loam, 2 to 15% slopes, (JCD) (moderately

O Encheirídion de Epicteto: Edição Bilíngue

Directory of Open Access Journals (Sweden)

Aldo Lopes Dinucci

2012-02-01

Full Text Available Edição bilíngue do Encheirídion de Epicteto, obra do aluno de Epicteto (55-135 e cidadão romano de origem grega Lúcio Flávio Arriano de Nicomédia (86-160. Tal tradução, produzida por Aldo Dinucci (doutor em filosofia pela PUC-RJ e professor associado do Departamento de Filosofia da UFS e Alfredo Julien (doutor em história pela USP e professor adjunto do Departamento de História da UFS, foi financiada pelo CNPq (edital MCT/CNPq 02/2009 - Ciências Humanas, Sociais e Sociais Aplicadas.

Annual Research Progress Report Fiscal Year 1992. Volume 2. Department of Clinical Investigation (Brooke Army Medical Center)

Science.gov (United States)

1992-01-01

Vesico-Colonic Anastomosis. (T) A-4-90 Botulinum Toxin Detection by Mouse Bioassay. (0) 294 A-5-90 Production of Mouse Positive and Negative Control...Protocol for Acute 518 Lymphocytic Leukemia. (0) POG 9005 ALinC 15: Dose Intensification of Methotrexate and 519 6- Mercaptopurine for ALL in Childhood...cultures, food products , serum and fecal specimens. Technical Approach: Pairs of mice are selected and anesthetized with 2 ml of halothane in an

The long term impact of the 1918 influenza pandemic in Norway

OpenAIRE

Bakken, Magnus Røthe; Husøy, Sigrid Johanne

2016-01-01

Advisor: Aline Bütikofer A growing literature show the negative effect of prenatal health shocks on childhood and adult outcomes. Several studies exploit disease outbreaks to find causal effects of in utero exposure on various outcomes. We build on the existing literature by applying theories of in utero health effects to Norwegian data. This thesis uses the 1918 Spanish Influenza pandemic as a natural experiment to investigate the impact of prenatal health shock on various ...

Results of the Second U.S. Manned Orbital Space Flight

Science.gov (United States)

1962-05-24

malfunctioning scanner which mitter was maintained in a standby condition 6 36- Turnaround 32- -- 0Automatic Gyro window alinement . Manual 28 A ASCS...system primarily controls the environment in which the astronaut oper- ates, both in the spacecraft cabin and in the pressure suit. Total pressure... controls and other objects within the first, the clamp ring explosive bolts, and then, cabin were relative to myself. I could reach the louder noise of

Flood Control Minnesota River, Minnesota, Mankato-North Mankato-Le Hillier. Design Memorandum Number 8. Part I. Location Study and Draft Supplement II to the Final Environmental Impact Statement for Bridge Relocations. Main Street, Trunk Highways 60 Bridge over the Minnesota River between Mankato and North Mankato.

Science.gov (United States)

1981-06-01

topography or in rugged terrain, majur road overcrossings may be attainable only by a forced alinement and rolling gradeline. Where there otherwise...Wisconsin PCB Interagency Task Force in 1976 indicated that the game fish in the Minnesota River near Mankato have higher polychlorinated biphenyl (PCB...Highway River Structures Job Sum 5,920,000.00 TOTAL BRIDGES $6,875,000.00 TOTAL ROADWAY AND BRIDGES $11,674,000.00 Force Accounts CNW T. Co. Track Removal

Department of Clinical Investigation: Annual Research Progress Report for Fiscal Year 1992. Volume 2

Science.gov (United States)

1993-01-01

A-5-90 Production of Mouse Positive and Negative Control Slides for 295 Use in Rabies FRA Test. (0) A-7-90 Clinical Investigation on the...Dose Intensification of Methotrexate and 519 6- Mercaptopurine for ALL in Childhood. (0) POG 9006 ALinC 15: Up-Front 6-MP/MTX vs. Up-Front Alternating 520...for the mouse bioassay as a means for detecting Clostridium botulinum toxin in cultures, food products , serum and fecal specimens. Technical Approach

Methods for determining the preatmospheric dimensions of meteorites

Science.gov (United States)

Ustinova, G. K.; Alekseev, V. A.; Lavrukhina, A. K.

1988-10-01

Methods are proposed for the determination of the preatmospheric size of a meteorite on the basis of data on its cosmogenic radionuclides. Optimal conditions for the application of each of these methods are presented together with the demonstration of their effectiveness. Estimates of relative dimensions determined by these methods are presented for the Harleton, St. Severin, Lost City, Peace River, Pribram, Dhajala, Innisfree, Bruderheim, Ehole, and Gorlovka chondrites and for the Iardymly, Boguslavka, Treysa, and Sikhote-Alin' iron meteorites.

Constantine Calafateanu, the greatest artist of Romanian modern art

Directory of Open Access Journals (Sweden)

Marković Kamenko M.

2016-01-01

Full Text Available Constantine Calafateanu (1911-1978 is one of the most important Romanian painters of the twentieth century. He studied French literature at the Sorbonne, but he also regularly visited two painting studios: La Grande Chaumiere and Julien Academy. On returning to Romania he did some teaching work, therefore, he started exhibiting relatively late in life. His first solo exhibition took place in 1965. The creation of this painter highlights two phases: the first one lasted until 1965 and the second one lasted from 1968 to the end of the painter's life. Calafateanu mostly painted landscapes (fall and winter, flowers, still life, and nudes.

The energy transition

International Nuclear Information System (INIS)

Passalacqua, Arnaud; Billes-Garabedian, Laurent; Jancovici, Jean-Marc; Arnoux, Mathieu; Auverlot, Dominique; Leguet, Benoit; Grandjean, Alain; Morel, Julien; Lambert, Quentin; Tranie, Jean-Pascal; Bureau, Dominique; Dron, Dominique; Beeker, Etienne

2013-01-01

This special dossier about energy transition is made of 10 contributions dealing with: thousands of years of energy transition (Jean-Marc Jancovici); a recurring problem after a thousand years of fight (Mathieu Arnoux); urban mobility: another energy story (Arnaud Passalacqua); an opportunity subjected to conditions for the French competitiveness (Dominique Auverlot, Benoit Leguet); Germany: an energy utopia or a role model? (Etienne Beeker); environment: the financing stakes (Dominique Dron); reconciling the economical, social and ecological stakes (Alain Grandjean); Sweden in the face of transportation challenge (Julien Morel, Quentin Lambert); India and China with a commitment to global warming (Jean-Pascal Tranie); training the energy transition managers (Dominique Bureau)

Actes de la conférence " Aux frontières de l'urbain. Petites villes du monde : émergence, croissance, rôle économique et social, intégration territoriale, gouvernance "
Conference Proceedings "At the Frontiers of Urban Space. Small towns of the world: emergence, growth, economic and social role, territorial integration, governance"

OpenAIRE

Moriconi Ebrard, François; Chatel, Catherine; Bordagi, Julien

2014-01-01

Sous la Direction de François Moriconi-Ebrard, Catherine Chatel et Julien Bordagi Éditeur : UMR ESPACE - Avignon, Case 19, 74 rue Louis Pasteur, 84029 Avignon Cedex Collection : Actes Avignon - ISBN : 978‐2‐9105‐4509‐1; Publication collective. La conférence internationale " Aux frontières de l'urbain " s'est déroulée à l'Université d'Avignon et des Pays de Vaucluse du 22 au 24 janvier 2014. Elle a été organisée à l'initiative d'un groupe de chercheurs de l'UMR 7300 ESPACE spécialistes de la v...

La sélection d'Aldébaran

Directory of Open Access Journals (Sweden)

Françoise Acquier

2014-09-01

Full Text Available Aldébaran est une revue électronique en libre accès qui propose une sélection de ressources documentaires en sciences humaines à travers des notices de sites et des conseils de recherche. Les notices présentées dans ce numéro ont été rédigées par Françoise Acquier (CRESSON, Grenoble, Fabrice Melka (IMAF, Julien Gillet (Cléo et Véronique Ginouvès (MMSH USR3125. Afriterra. The Cartographic Free Library http://aldebaran.revues.org/6775 La fondation Afriterra, à but non lucratif, est une bibl...

Development of a Menu Driven Materials Data Base for Use on Personal Computers

Science.gov (United States)

1992-07-01

written permission. Copyright Is the responsibility of the Director Publishing and Marketing , AGPS. Enquiries should be directed to the Manager, AGPS...PROGRAM LISTING A-2-1 Program MOB; uses crt; label levell,level2,level3,shutdown,dis;play; var options,code, nlines ,nmeflitemp,i,j4,k :integer; w,chl,ch2,ch3...char; menus :array [I. .1001 of st~ring[801; nline :array [l. .100] of integer; s2 :string[21; control :string[4]; aline :string[801; inm,iflt :text

CMS Comic Book

CERN Document Server

Gill, Karl Aaron

2006-01-01

Titled "CMS Particle Hunter," this colorful comic book style brochure explains to young budding scientists and science enthusiasts in colorful animation how the CMS detector was made, its main parts, and what scientists hope to find using this complex tool. Book invites young students to get involved in particle physics themselves to join the adventure. Written by Dave Barney and Aline Guevera. Layout and drawings by Eric Paiharey and Frederic Vignaux. Available in English, French, German, Italian, Spanish and Portuguese. Year Produced: 2006. Update: September 2013.

REIGNY, Actes diplomatiques du XIIe siècle

Directory of Open Access Journals (Sweden)

Marlène Hélias-Baron

2008-07-01

Full Text Available Tout a commencé en 1104 quand deux ermites, Guérin et Gérard, ont obtenu d’Anséric chevalier d’Avallon et de Guy de Noyers la terre de Saint-Pierre située à proximité de Joux-la-Ville, dans le diocèse d’Autun. Leur aura de sainteté attira des disciples et leur communauté, installée en un lieu fort humide, justement appelé Fons humidus, Fontemoy, se transforma progressivement en un petit monastère. A la mort du deuxième abbé, Julien, au cours de l’année 1128, comme de nombreuses autres communa...

Book review: Seismic acquisition from yesterday to tomorrow

Science.gov (United States)

Haines, Seth

2012-01-01

In this 236-page volume, Julien Meunier presents a thorough description of P-wave seismic data acquisition. The treatment includes historical aspects along with some discussion of trends for the future, but the main focus is on present-day approaches and their theoretical underpinnings. Although it was written as the text for the 2011 Distinguished Instructor Short Course, I found the book to be quite readable in a stand-alone context and of considerable interest despite my being a bit outside of the primary target audience. I believe that the book would be valuable as an auxiliary text for a graduate-level course, or even as reading for independent study on the topic.

CP-recursion and the derivation of verb second in Germanic main and embedded clauses

DEFF Research Database (Denmark)

Vikner, Sten

2017-01-01

, this is normally not the case for all types of embedded clauses, as e. g. embedded questions (almost) never allow V2 (Julien 2007, Vikner 2001, though see McCloskey 2006 and Biberauer 2015). As in Nyvad et al. (2016), I will explore a particular derivation of (embedded) V2, in terms of a cP/CP-distinction, which...... may be seen as a version of the CP-recursion analysis (deHaan & Weerman 1986, Vikner 1995 and many others). The idea is that because embedded V2 clauses do not allow extraction, whereas other types of CP-recursion clauses do (Christensen et al. 2013a; Christensen et al. 2013b; Christensen & Nyvad 2014...

Water migration of macroelements in coniferous-broad-leaved forests of Sikhote-Alin

OpenAIRE

N. K. Kozhevnikova; T. N. Lutsenko; A. G. Boldeskul; S. Yu. Lupakov; V. V. Shamov

2017-01-01

In the paper, the natural water chemical composition spatial variability studies results in the mountain forest catchment are presented. It’s shown that the catchment biotic components’ impact upon water chemical composition is detected even at input as atmospheric precipitation. The input fluxes are acid, sulfate ones with high ratio of hydrogen, potassium and dissolved organic matter. Diversity of ecotopic conditions determines the further transformation of natural water chemical composit...

Water migration of macroelements in coniferous-broad-leaved forests of Sikhote-Alin

Directory of Open Access Journals (Sweden)

N. K. Kozhevnikova

2017-06-01

Full Text Available In the paper, the natural water chemical composition spatial variability studies results in the mountain forest catchment are presented. It’s shown that the catchment biotic components’ impact upon water chemical composition is detected even at input as atmospheric precipitation. The input fluxes are acid, sulfate ones with high ratio of hydrogen, potassium and dissolved organic matter. Diversity of ecotopic conditions determines the further transformation of natural water chemical composition. The role of tree crowns in the transformation increases while the crown closure and stands’ age increase. According to macrocomponents transformation and rain acidity neutralization, forest associations form the sequence: mixed > coniferous > young deciduous ones. Dissolved organic carbon (DOC, potassium and calcium become the main components of water chemical composition, while sulfates dominate among anions. For vegetation period, 9–11 kg/ha of sulfates come below tree crown. Biogenic elements transport is gradually limited in soil profile at the migration stage. Sulfate-potassium composition throughfall in spruce-fir and secondary forests community transforms into sulfate-sodium-calcium. Hydrocarbonates predominate in soil water in broad-leaved-pine type of forest, and potassium output decreases 10 times. Geochemical type of river water keeps features of chemical composition of soil drained by river section. Negligible output of sulfates, hydrocarbonates and calcium from ecosystem is established for the headwaters. Negative balance of hydrocarbonates and calcium is compensated by significant input of these components with throughfall at catchments with predominantly pine-broad-leaved forest types.

Crozant – Château de Crozant

OpenAIRE

Chaillou, Mélanie

2013-01-01

Identifiant de l'opération archéologique : 2785 Date de l'opération : 2007 - 2008 (SP) Inventeur(s) : Chaillou Mélanie (HADES) La porterie du château de Crozant fait l’objet d’un chantier de consolidation depuis septembre 2007. Cette partie de la forteresse est composée de quatre grands ensembles : la tour E à l’ouest (déjà en partie fouillée par Julien Denis en 2004), séparée de la tour C au sud-est par la culée du pont qui donnait accès au château (passage A), et enfin la tour D flanquée au...

A century of Pharmaceutical and professorial presidency at the Societe lorraine de mycologie> (1911-2011).

Science.gov (United States)

Labrude, Pierre

2016-06-01

The society was created in 1911 at the Ecole supirieure de pharmacie of Nancy by professor Julien Godfrin wno was the chairman of the school and wno becamed its first president. But Godfrin died in 1913. The second president was Auguste Sartory who was extremely active in spite of the war but who leaved Nancy at its end to be named as a professor at the new school of pharmacy in Strasbourg. Four presidents followed each other during these years after Sartory: Pierre Seyot, Emile Steimetz, Pierre Lectard and Frangois Mortier. All of them were pharmacists and professors. During this century, the society was always associated to the school and to the faculty for the teaching of mycology to pharmacy students and other lovers.

Identifying ecological corridors for Amur tigers (Panthera tigris altaica) and Amur leopards (Panthera pardus orientalis).

Science.gov (United States)

Miquelle, Dale G; Rozhnov, Vyachaslav V; Ermoshin, Victor; Murzin, Andre A; Nikolaev, Igor G; Hernandez-Blanco, Jose A; Naidenko, Sergie V

2015-07-01

The rapid explosion of human populations and the associated development of human-dominated landscapes have drastically reduced and fragmented habitat for tigers (Panthera tigris) and leopards (Panthera pardus) across Asia, resulting in multiple small populations. However, Amur tiger (Panthera tigris altaica) habitat in Russia has remained largely interconnected, except for a break between tigers in southwest Primorye and the southern Sikhote-Alin Mountains. This habitat patch in southwest Primorye also retains the last population of Amur leopards (Panthera pardus orientalis). Genetic differentiation of tigers in southwest Primorye and the Sikhote-Alin Mountains along with survey data suggest that habitat fragmentation is limiting movement of tigers and leopards across the Razdolnaya River basin. We looked at historical and recent survey data on tigers and leopards and mapped existing cover types to examine land-use patterns of both large felids and humans in the development strip along the Razdolnaya River. We then used least-cost distance analyses to identify the most effective potential corridor to retain connectivity for large felids between Land of the Leopard National Park and Ussuriskii Zapovednik (Reserve). We identified a single potential corridor that still exists with a total distance of 62.5 km from Land of the Leopard National Park to Ussuriskii Zapovednik, mostly (93%) through forested habitat. We recommend formal recognition of a Razdolnaya ecological corridor and provide specific recommendations for each of 3 proposed management sections. © 2015 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and Wiley Publishing Asia Pty Ltd.

Entornos termodinámicos. Una cartografía crítica en torno a la energía y la arquitectura

OpenAIRE

García-Germán Trujeda, Javier

2014-01-01

En los últimos años, y a la luz de los retos a los que se enfrenta la sociedad, algunas voces están urgiendo a dejar atrás los paradigmas modernos —eficiencia y rendimiento— que sustentan a las llamadas prácticas sostenibles, y están alentando a repensar, en el contexto de los cambios científicos y culturales, una agenda termodinámica y ecológica para la arquitectura. La cartografía que presenta esta tesis doctoral se debe de entender en este contexto. Alineándose con esta necesidad, se esfue...

Avaliação da análise microscópica tradicional e do analisador automatizado IQ200R no exame de urina

OpenAIRE

Henneberg, José Ricardo

2014-01-01

Orientador : Prof. Dr. Aguinaldo José do Nascimento Co-orientadora : Profª. Drª. Aline Borsato Hauser Dissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências da Saúde, Programa de Pós-Graduação em Ciências Farmacêuticas. Defesa: Curitiba, 05/09/2014 Inclui referências Área de concentração: Análises clínicas Resumo: A análise de urina é um dos exames mais solicitados na rotina laboratorial, por ser um procedimento não invasivo, com facilidade na obtenção da am...

High-Energy Electron Beam Application to Air Pollutants Removal

International Nuclear Information System (INIS)

Ighigeanu, D.; Martin, D.; Manaila, E.; Craciun, G.; Calinescu, I.

2009-01-01

The advantage of electron beam (EB) process in pollutants removal is connected to its high efficiency to transfer high amount of energy directly into the matter under treatment. Disadvantage which is mostly related to high investment cost of accelerator may be effectively overcome in future as the result of use accelerator new developments. The potential use of medium to high-energy high power EB accelerators for air pollutants removal is demonstrated in [1]. The lower electrical efficiencies of accelerators with higher energies are partially compensated by the lower electron energy losses in the beam windows. In addition, accelerators with higher electron energies can provide higher beam powers with lower beam currents [1]. The total EB energy losses (backscattering, windows and in the intervening air space) are substantially lower with higher EB incident energy. The useful EB energy is under 50% for 0.5 MeV and about 95% above 3 MeV. In view of these arguments we decided to study the application of high energy EB for air pollutants removal. Two electron beam accelerators are available for our studies: electron linear accelerators ALIN-10 and ALID-7, built in the Electron Accelerator Laboratory, INFLPR, Bucharest, Romania. Both accelerators are of traveling-wave type, operating at a wavelength of 10 cm. They utilize tunable S-band magnetrons, EEV M 5125 type, delivering 2 MW of power in 4 μ pulses. The accelerating structure is a disk-loaded tube operating in the 2 mode. The optimum values of the EB peak current IEB and EB energy EEB to produce maximum output power PEB for a fixed pulse duration EB and repetition frequency fEB are as follows: for ALIN-10: EEB = 6.23 MeV; IEB =75 mA; PEB 164 W (fEB = 100 Hz, EB = 3.5 s) and for ALID-7: EEB 5.5 MeV; IEB = 130 mA; PEB = 670 W (fEB = 250 Hz, EB = 3.75 s). This paper presents a special designed installation, named SDI-1, and several representative results obtained by high energy EB application to SO 2 , NOx and VOCs

Alma sensible, romanticismo exaltado y suicidio. Sobre la novela Voyleano o la exaltación de las pasiones (1827, de Estanislao de Cosca Vayo y Lamarca

Directory of Open Access Journals (Sweden)

Sebold, Russel P.

2014-12-01

Full Text Available The character Voyleano has models in the suicide Werther, by Goethe, and in the death-desiring Tediato in the Lugubrious Nights, by Cadalso. The creation of the figure of Voyleano depends on the new sensibility of the Enlightenment, romantic cosmic grief, and the exaltation of romantic psychology. In the novel by Vayo the Napoleonic invasion of Spain is depicted, and this atmosphere lends itself to libertine seductions, betrayals, great disillusionments, and the loss of faith. Voyleano, like don Quijote, like Julien Sorel, like Emma Bovary, and like several characters from Larra and Mesonero Romanos has sought a model or logos in an earlier character. After don Quijote Voyleano is the first of all of them. Voyleano considers the physical act of suicide lacking in nobility and cowardly, and although he is inspired by Werther, he is attracted to Tediato’s way of committing suicide while avoiding the physical act of suicide.El personaje Voyleano tiene modelos en el suicida Werther, de Goethe, y en el deseoso de morir Tediato de las Noches lúgubres, de Cadalso. Entran en la confección de la figura de Voyleano la nueva sensibilidad de la Ilustración, el dolor cósmico romántico y la exaltación de la psicología romántica. En la novela de Vayo se vive la invasión napoleónica de España, y tal ambiente se presta a seducciones libertinas, traiciones, grandes desilusiones y pérdida de la fe. Voyleano, como don Quijote, como Julien Sorel, como Emma Bovary y como varios personajes de Larra y Mesonero Romanos ha buscado un modelo o logos en un personaje anterior. Después de don Quijote, Voyleano es el primero de todos ellos. A Voyleano le parece poco noble y cobarde el acto físico del suicidio, y aunque se inspira en Werther, le atrae en Tediato el modo de suicidarse evitando el acto físico del suicidio.

Causes and consequences of obesity: epigenetics or hypokinesis?

Directory of Open Access Journals (Sweden)

Graham MR

2015-09-01

Full Text Available Michael R Graham,1 Julien S Baker,2 Bruce Davies3 1Llantarnam Research Academy, Cwmbran, Torfaen, UK; 2Exercise Science Research Laboratory, Institute of Clinical Exercise and Health Science, School of Science, University of the West of Scotland, Hamilton, UK; 3Science Department, University of South Wales, Newport, UKEpigenetics can be defined as the study of heritable changes that affect gene function without modification of the deoxyribonucleic acid (DNA sequence.1 The transfer of epigenetic marks through generations is not well understood, and their transmission is in dispute.2 Epigenetic marks are tissue-specific and include DNA methylation and histone modifications that mediate biological processes, such as imprinting (Figure 1. Many imprinted genes are regulators of gene expression controlling growth. Imprinting disorders often feature obesity as one of their characteristics.3

Trends in information behaviour research

DEFF Research Database (Denmark)

Greifeneder, Elke Susanne

2014-01-01

behaviour related publication venues between 2012 and 2014. Analysis. Publication titles, authors, years, publication venue, methods and topics were collected and quantitatively analysed. Results. Qualitative methods still dominate information behaviour research. Content analysis and participatory designs......Introduction. This paper traces current trends in information behaviour research, both in terms of methods and topics. Results are put into relation to the previous trend analysis by Julien et al. (2011) and Vakkari (2008). Method. Trends derive from a publication analysis taken from information...... are gaining terrain. Information seeking is still the major topic of interest. Important newer topics are studies focusing on users’ context and on special needs. Conclusion. Information behaviour research has evolved a great deal over the last years and has taken on new methods and new topics. A discussion...

Frequency and number of ultrasound lung rockets (B-lines) using a regionally based lung ultrasound examination named vet BLUE (veterinary bedside lung ultrasound exam) in dogs with radiographically normal lung findings.

Science.gov (United States)

Lisciandro, Gregory R; Fosgate, Geoffrey T; Fulton, Robert M

2014-01-01

Lung ultrasound is superior to lung auscultation and supine chest radiography for many respiratory conditions in human patients. Ultrasound diagnoses are based on easily learned patterns of sonographic findings and artifacts in standardized images. By applying the wet lung (ultrasound lung rockets or B-lines, representing interstitial edema) versus dry lung (A-lines with a glide sign) concept many respiratory conditions can be diagnosed or excluded. The ultrasound probe can be used as a visual stethoscope for the evaluation of human lungs because dry artifacts (A-lines with a glide sign) predominate over wet artifacts (ultrasound lung rockets or B-lines). However, the frequency and number of wet lung ultrasound artifacts in dogs with radiographically normal lungs is unknown. Thus, the primary objective was to determine the baseline frequency and number of ultrasound lung rockets in dogs without clinical signs of respiratory disease and with radiographically normal lung findings using an 8-view novel regionally based lung ultrasound examination called Vet BLUE. Frequency of ultrasound lung rockets were statistically compared based on signalment, body condition score, investigator, and reasons for radiography. Ten left-sided heart failure dogs were similarly enrolled. Overall frequency of ultrasound lung rockets was 11% (95% confidence interval, 6-19%) in dogs without respiratory disease versus 100% (95% confidence interval, 74-100%) in those with left-sided heart failure. The low frequency and number of ultrasound lung rockets observed in dogs without respiratory disease and with radiographically normal lungs suggests that Vet BLUE will be clinically useful for the identification of canine respiratory conditions. © 2014 American College of Veterinary Radiology.

Model-based gene set analysis for Bioconductor.

Science.gov (United States)

Bauer, Sebastian; Robinson, Peter N; Gagneur, Julien

2011-07-01

Gene Ontology and other forms of gene-category analysis play a major role in the evaluation of high-throughput experiments in molecular biology. Single-category enrichment analysis procedures such as Fisher's exact test tend to flag large numbers of redundant categories as significant, which can complicate interpretation. We have recently developed an approach called model-based gene set analysis (MGSA), that substantially reduces the number of redundant categories returned by the gene-category analysis. In this work, we present the Bioconductor package mgsa, which makes the MGSA algorithm available to users of the R language. Our package provides a simple and flexible application programming interface for applying the approach. The mgsa package has been made available as part of Bioconductor 2.8. It is released under the conditions of the Artistic license 2.0. peter.robinson@charite.de; julien.gagneur@embl.de.

Interfon

CERN Document Server

Interfon

2011-01-01

Nouveauté 2011 !!!! Notre nouveau partenaire VITAM’PARC vous ouvre ses portes pour vos activités « Loisirs  » : L’eau (bassins natation, toboggans, balnéoforme,…) La raquette (squash, badminton,…) L’escalade (murs pour tous les âges) Le bien être (spas, sauna, soins corporels,…) Et bien d’autres activités : shopping, restaurant …   VENTE DE BILLETS A TARIFS REDUITS A NOS COMPTOIRS (Bâtiment 504 ou au Technoparc) 500, Route des Envignes – 74160 Neydens (St-Julien-en-Genevois) www.vitamparc.com * * * * *     Information CERN : Tél. 73339 de 12h30 à 15h30 e-mail : interfon@cern.ch www.interfon.fr Permanence Mutuelle le jeudi, Tél. 73939 de 13h à 16h30 Siège de St-Genis, T&...

Forest litter stocks in Korean pine-broad-leaved forests of the southern Sikhote Alin

Directory of Open Access Journals (Sweden)

A. V. Ivanov

2015-10-01

Full Text Available The article presents the data on the forest litter of the Korean pine-broad-leaved forests of the South of Primorsky krai. The focus of the research is plantations dominated by Korean pine; areas of the main tree species with ages of 50, 80, 130 and 200 years were selected. The dynamics of the forest litter stock in the pine and broadleaved forests of different ages according to the measurement results for the season in 2014 is stated. In the studied plantation, the forest litter stock varies between 9.7–20.3 t ha-1. The greatest value of the forest litter stock is recorded in old-growth cedar forest (200 years. Relatively high power and the stock of litter are typical for young Korean pine forest that can explain the lower speed of the litter properties change against the dynamics of taxation indicators of the forest stand. The difference between the amount of the litter in the 200-year-old and remaining pine trees are statistically significant at p = 0.05. The dependence of the litter power on the age is not revealed. The coefficient of the forest litter decomposition ranges from 2.55–10.60 that characterizes the high speed of its rotting. The highest coefficient of the litter decomposition has an old-growing pine forest. The schedule of seasonal humidity fluctuations of the forest litter on the chosen plot is made; with increasing cedar forest age, the volumetric moisture content of the forest litter increases; volumetric moisture content on the plots remain relatively unchanged during the season. The area of the Korean pine forests of Primorsky State Academy of Agriculture is 6835 ha. The amount of carbon stock in the forest litter is 38.7 thousand tons C. in this area, while the system of regional assessment of the forest carbon balance estimates this index as 24.3 tons С. The data obtained can be used to adjust the coefficients of regional assessment of the forest carbon balance for cedar forests of Primorsky krai.

Lung ultrasonography to diagnose pneumothorax of the newborn.

Science.gov (United States)

Liu, Jing; Chi, Jing-Han; Ren, Xiao-Ling; Li, Jie; Chen, Ya-Juan; Lu, Zu-Lin; Liu, Ying; Fu, Wei; Xia, Rong-Ming

2017-09-01

To explore the reliability and accuracy of lung ultrasound for diagnosing neonatal pneumothorax. This study was divided into two phases. (1) In the first phase, from January 2013 to June 2015, 40 patients with confirmed pneumothorax had lung ultrasound examinations performed to identify the sonographic characteristics of neonatal pneumothorax. (2) In the second phase, from July 2015 to August 2016, lung ultrasound was undertaken on 50 newborn infants with severe lung disease who were suspected of having pneumothorax, to evaluate the sonographic accuracy and reliability to diagnose pneumothorax. (1) The main ultrasonic manifestations of pneumothorax are as follows: ① lung sliding disappearance, which was observed in all patients (100%); ② the existence of the pleural line and the A-line, which was also observed in all patients (100%); ③ the lung point, which was found in 75% of the infants with mild-moderate pneumothorax but not found to exist in 25% of the severe pneumothorax patients; ④ the absence of B-lines in the area of the pneumothorax (100% of the pneumothorax patients); and ⑤ no lung consolidation existed in the area of the pneumothorax (100% of the pneumothorax patients). (2) The accuracy and reliability of the lung sonographic signs of lung sliding disappearance as well as the existence of the pleural line and the A-line in diagnosing pneumothorax were as follows: 100% sensitivity, 100% specificity, 100% positive predictive value, and 100% negative predictive value. When the lung point exists, the diagnosis is mild-moderate pneumothorax, whereas if no lung point exists, the diagnosis is severe pneumothorax. Lung ultrasound is accurate and reliable in diagnosing and ruling out neonatal pneumothorax and, in our study, was found to be as accurate as chest X-ray. Copyright © 2017 Elsevier Inc. All rights reserved.

CH{sub 3} and CD{sub 3} radicals isolated in argon: high resolution ESR spectra and analysis by three-dimensional quantum rotor model. A case study of low temperature quantum effects on radicals

Energy Technology Data Exchange (ETDEWEB)

Shiotani, Masaru; Yamada, Tomoya; Komaguchi, Kenji [Hiroshima Univ., Higashi-Hiroshima (Japan). Faculty of Engineering; Benetis, N.P.; Lund, A.; Soernes, A.R.

1998-10-01

The present study deals with high resolution isotropic ESR spectra of the CH{sub 3} and CD{sub 3} radicals isolated in solid argon matrix at low temperature from 4 K to 40 K. Argon gases mixed with methane (Ar/methane {approx_equal} 500 mole ratio) were condensed at the end of Suprasile ESR tube at 4.2 K. Methyl radicals were generated by X-ray irradiation at 4 K and subjected to an ESR study. The 6.0 K ESR spectrum of the CH{sub 4}/Ar system is shown in Fig. 1. For CH{sub 3} radical the {sup 1}H hyperfine (hf) quartet was observed with an equal intensity (A-lines). The E-lines were absent at 4 K, but became visible at m{sub F} = {+-}1/2 positions above 12 K increased with temperature. The CD{sub 3} gave a peculiar spectrum at 4 K with an abnormally strong central singlet superimposed on a much weaker seven line spectrum of a freely rotating CD{sub 3}. The temperature dependent spectra showed clear quantum effects due to three-dimensional spin-rotation couplings. The spectra were analyzed with the following assumptions: (a) a planar D{sub 3} geometry, (b) a free and three-dimensional quantum rotation and (c) a thermally isolated radical. Application of the Pauli principle in combination to the D{sub 3} point group resulted in interesting selections for ESR-transitions for both the CH{sub 3} and CD{sub 3} spectra. That is, the {sup 1}H hf quartet of CH{sub 3} radical (A-lines) was attributed to the rotational ground state, J=0, with totally symmetric A{sub 1} nuclear states. The central strong singlet of CD{sub 3} was attributed to one spin-rotation state with A{sub 2} antisymmetric nuclear states at the lowest rotational level of J=0. (author)

Cine postcolonial y de género. La diáspora afro-caribeña en el Reino Unido

Directory of Open Access Journals (Sweden)

Durán Almarza, Emilia María

2012-12-01

Full Text Available This article offers a critical re-evaluation of films directed by women of Caribbean descent in the United Kingdom. Although their presence in the British tradition is limited, given the marginal position they occupy as a result of the combination of variables such as race, ethnicity, gender, and/or social class, their contribution to British, Afro-diasporic and feminist film traditions cannot be underestimated. Drawing on comparative and transcultural approaches to analyse The Passion of Remembrance, co-directed by Maurine Blackwood and Isaac Julien, and Dreaming Rivers, directed by Martine Atille, both belonging to Sankofa Film Collective, this study highlights the multiple ways in which their work contributed to epistemological developments in the sphere of the so-called "British Black Arts Movement" of the 80s and 90s, as well as to the establishment of what has been called British postcolonial filmmaking.

El presente artículo trata de ofrecer una re-evaluación crítica del cine dirigido por mujeres de ascendencia caribeña en el Reino Unido. Si bien la presencia de directoras afro-caribeñas en la tradición británica es limitada, dada la posición marginal que ocupan como resultado de la combinación de variables como raza, etnicidad, género, y/o clase social, no se puede desestimar el alcance de su aportación a las tradiciones fílmicas femenina, británica y afro-diaspórica. Aplicando un enfoque comparativo y transcultural a The Passion of Remembrance, codirigida por Maurine Blackwood e Isaac Julien, y Dreaming Rivers, dirigida por Martine Atille, ambas pertenecientes al colectivo Sankofa, este estudio pone de manifiesto las múltiples formas en que sus obras contribuyeron tanto al desarrollo epistemológico del movimiento de las artes británicas negras (“British Black Arts Movement” en las décadas de los años 80 y 90, como al establecimiento de lo que se ha venido a llamar el cine

Luciano Maiani and Jean Iliopoulos awarded the Dirac Medal

CERN Multimedia

2007-01-01

Luciano Maiani, when he was Director-General of CERN. Jean Iliopoulos in 1999. (©CNRS Photothèque - Julien Quideau)On 8 August, the 2007 Dirac Medal, one of the most prestigious prizes in the fields of theoretical physics and mathematics, was awarded to Luciano Maiani, professor at Rome’s La Sapienza University and former Director-General of CERN, and to Jean Iliopoulos, emeritus Director of Research at the CNRS Laboratory of Theoretical Physics. The medal was awarded to both physicists for their joint "work on the physics of the charm quark, a major contribution to the birth of the Standard Model, the modern theory of Elementary Particles." Founded by the Abdus Salam International Centre for Theoretical Physics (ICTP) in 1985, the Dirac Medal is awarded annually on 8 August, the birthday of the famous physicist Paul Dirac, winner of the 1933 Nobel Prize for Physics. It is awarded to ...

A Tribute to J. C. Sprott

Science.gov (United States)

Nazarimehr, Fahimeh; Jafari, Sajad; Chen, Guanrong; Kapitaniak, Tomasz; Kuznetsov, Nikolay V.; Leonov, Gennady A.; Li, Chunbiao; Wei, Zhouchao

2017-12-01

In honor of his 75th birthday, we review the prominent works of Professor Julien Clinton Sprott in chaos and nonlinear dynamics. We categorize his works into three important groups. The first and most important group is identifying new dynamical systems with special properties. He has proposed different chaotic maps, flows, complex variable systems, nonautonomous systems, partial differential equations, fractional-order systems, delay differential systems, spatiotemporal systems, artificial neural networks, and chaotic electrical circuits. He has also studied dynamical properties of complex systems such as bifurcations and basins of attraction. He has done work on generating fractal art. He has examined models of real-world systems that exhibit chaos. The second group of his works comprise control and synchronization of chaos. Finally, the third group is extracting dynamical properties of systems using time-series analysis. This paper highlights the impact of Sprott’s work on the promotion of nonlinear dynamics.

Applied probability and stochastic processes

CERN Document Server

Sumita, Ushio

1999-01-01

Applied Probability and Stochastic Processes is an edited work written in honor of Julien Keilson. This volume has attracted a host of scholars in applied probability, who have made major contributions to the field, and have written survey and state-of-the-art papers on a variety of applied probability topics, including, but not limited to: perturbation method, time reversible Markov chains, Poisson processes, Brownian techniques, Bayesian probability, optimal quality control, Markov decision processes, random matrices, queueing theory and a variety of applications of stochastic processes. The book has a mixture of theoretical, algorithmic, and application chapters providing examples of the cutting-edge work that Professor Keilson has done or influenced over the course of his highly-productive and energetic career in applied probability and stochastic processes. The book will be of interest to academic researchers, students, and industrial practitioners who seek to use the mathematics of applied probability i...

Type I and type II residual stress in iron meteorites determined by neutron diffraction measurements

Science.gov (United States)

Caporali, Stefano; Pratesi, Giovanni; Kabra, Saurabh; Grazzi, Francesco

2018-04-01

In this work we present a preliminary investigation by means of neutron diffraction experiment to determine the residual stress state in three different iron meteorites (Chinga, Sikhote Alin and Nantan). Because of the very peculiar microstructural characteristic of this class of samples, all the systematic effects related to the measuring procedure - such as crystallite size and composition - were taken into account and a clear differentiation in the statistical distribution of residual stress in coarse and fine grained meteorites were highlighted. Moreover, the residual stress state was statistically analysed in three orthogonal directions finding evidence of the existence of both type I and type II residual stress components. Finally, the application of von Mises approach allowed to determine the distribution of type II stress.

Orienteering Club

CERN Multimedia

Le Club d’orientation du CERN

2017-01-01

COURSE ORIENTATION Finale de la coupe d’automne Le club d’orientation du CERN (COC Genève) a organisé sa dernière course populaire de la saison samedi 4 novembre au lieu-dit Les Terrasses de Genève (74). Cette 9e épreuve qui se courait sous la forme d’un One-Man-Relay, clôturait ainsi la coupe genevoise d’automne dont les lauréats sont : Circuit technique long : 1. Julien Vuitton (COC Genève), 2. Berni Wehrle (COC Genève), 3. Christophe Vuitton (COC Genève). Circuit technique moyen : 1. Vladimir Kuznetsov (Lausanne-Jorat), 2. J.-Bernard Zosso (COC Genève), 3. Laurent Merat (O’Jura). Circuit technique court : 1. Thibault Rouiller (COC Genève), 2. exæquo Lennart Jirden (COC Genève) et Katya Kuznetsova (Lausanne-Jorat). Circuit facile moyen : 1. Tituan Barge ...

Orienteering Club

CERN Multimedia

Le Club d’orientation du CERN

2017-01-01

COURSE ORIENTATION Finale de la coupe d’automne Le club d’orientation du CERN (COC Genève) a organisé sa dernière course populaire de la saison samedi 4 novembre au lieu-dit Les Terrasses de Genève (74). Cette 9e épreuve qui se courait sous la forme d’un One-Man-Relay, clôturait ainsi la coupe genevoise d’automne dont les lauréats sont : Circuit technique long : 1. Julien Vuitton (COC Genève), 2. Berni Wehrle (COC Genève), 3. Christophe Vuitton (COC Genève). Circuit technique moyen : 1. Vladimir Kuznetsov (Lausanne-Jorat), 2. J.-Bernard Zosso (COC Genève), 3. Laurent Merat (O’Jura). Circuit technique court : 1. Thibault Rouiller (COC Genève), 2. exæquo Lennart Jirden (COC Genève) et Katya Kuznetsova (Lausanne-Jorat). Circuit facile moyen : 1. Tituan Barge...

Fractal Geometry and Stochastics V

CERN Document Server

Falconer, Kenneth; Zähle, Martina

2015-01-01

This book brings together leading contributions from the fifth conference on Fractal Geometry and Stochastics held in Tabarz, Germany, in March 2014. The book is divided into five sections covering different facets of this fast developing area: geometric measure theory, self-similar fractals and recurrent structures, analysis and algebra on fractals, multifractal theory, and random constructions. There are state-of-the-art surveys as well as papers highlighting more specific recent advances. The authors are world-experts who present their topics comprehensibly and attractively. The book provides an accessible gateway to the subject for newcomers as well as a reference for recent developments for specialists. Authors include: Krzysztof Barański, Julien Barral, Kenneth Falconer, De-Jun Feng, Peter J. Grabner, Rostislav Grigorchuk, Michael Hinz, Stéphane Jaffard, Maarit Järvenpää, Antti Käenmäki, Marc Kesseböhmer, Michel Lapidus, Klaus Mecke, Mark Pollicott,  Michał Rams, Pablo Shmerkin, and András Te...

Orienteering club

CERN Document Server

Club d'orientation

2011-01-01

Après Chancy, rendez-vous à Lamoura La 7e étape de la Coupe Genevoise de printemps organisée dans la forêt de Chancy/Valleiry s’est déroulée sous la pluie tant attendue par Dame Nature mais moins par les coureurs. Le parcours technique long a été remporté par Berni Wehrle. Sur le parcours technique moyen, Jean-Bernard Zosso prend la première place. Emmanuel Morin remporte le technique court, Pieric Matera le facile moyen et Julien Vuitton, comme d’habitude, gagne le facile court. Exceptionnellement la prochaine étape de la Coupe Genevoise de printemps aura lieu dimanche 22 mai. Le rendez-vous de cette 8e étape sera à Lamoura. Les inscriptions se feront à partir de 9h et les départs entre 9h30 et 11h. Retenez également que la 9e étape est prévue le 28 mai au Semnoz. Les inscriptions ...

[How free is free will? Neuro-scientific and philosophical aspects of motivation and decision-making].

Science.gov (United States)

Hinterhuber, Hartmann

2012-01-01

The question concerning the postulated freedom of will continues to occupy the neuro-sciences, psychiatry, law and neuro-philosophy. Do current research results really show that freedom and responsibility were only illusions, since previously supposed free decisions were only accompanying features of long held neuronal activations? Did Julien de La Mettrie have a great vision, when, already in the Eighteenth Century, he expected a "monsieur Machine"?This article attempts to summarize and evaluate findings that are currently available. The autonomy of human action is not only founded in a subjectively perceived act of will but far more in the ability of the human being to act according to an inner drive which is steered consciously and rationally. The autonomy of human action is not only restricted to the perceived ego, but comprises body and soul, brain and spirit and consequently the whole human being with all their characteristics, values and aims. Modern science thereby supports the old philosophical theory of a conditional freedom of will.

Orienteering Club

CERN Document Server

Club d'orientation

2013-01-01

De jour comme de nuit Les amateurs de course d’orientation ont pu s’en donner à cœur joie ce week-end puisqu’ils avaient la possibilité de courir sur deux épreuves en moins de 24 heures. En effet, le club du CERN organisait une course de nuit aux Evaux et la 7e étape de la coupe genevoise se tenait samedi après-midi dans les bois du Grand Jorat à Savigny. Les vainqueurs pour chaque course sont : Technique long CO de nuit: Julien Charlemagne, SOS Sallanches CO samedi: Philipp Khlebnikov, ANCO   Technique moyen CO de nuit: Céline Zosso, CO CERN CO samedi: Pavel Khlebnikov, ANCO Technique court CO de nuit: Colas Ginztburger, SOS Sallanches CO samedi: Victor Kuznetsov, COLJ Lausannne Facile moyen CO de nuit: Gaëtan Rickenbacher, CO CERN CO samedi: Tamas Szoke   Facile court CO de nuit:Oriane Rickenbacher, CO CERN CO samedi: Katya Kuznetsov...

Over one million followers reached in CERN TweetUp

CERN Multimedia

Katherine Chapman

2012-01-01

More than a million followers were reached on Twitter during CERN’s first ever “TweetUp”. On 25 July, 5 lucky Twitter followers, or "Tweeps" as they are known, visited CERN to take part in events held on the same day with the STS-134 astronauts. The Tweetup gave the online community a chance to ask questions and explore areas of CERN through the eyes of the tweeps, prompting over 1,000 tweets and re-tweets between them in 24 hours.   Loic Bommersbach, Lucy McKenna, Astrid Chantelauze (KIT), Nick Howes, Angeliki Kanellopoulou, Maud Ali-Cherif (ESA), Julien Harrod (ESA), Katherine Chapman (CERN), and Simon Bierwald outside the CERN Control Centre. Five winners of a competition announced on Twitter were invited to come to CERN and spend a day behind the scenes, taking part in events organised to celebrate the AMS experiment that was launched in May 2011. The aim was to give tweeps the opportunity to explore CERN and share their experiences, allowi...

Orienteering Club

CERN Multimedia

Le Club d’orientation du CERN

2017-01-01

Calendrier des courses de la Coupe Genevoise – printemps 2017 Club d'orientation - Julien,  jeune membre du club. Le Club d’orientation du CERN, en partenariat avec d’autres clubs de la région, vous propose une série de courses populaires, qui se dérouleront des deux côtés de la frontière franco-suisse, à savoir : Samedi 1 avril : Pougny/Challex (01) Samedi 8 avril: Ballens (VD) Samedi 22 avril: Apples (VD) Samedi 29 avril: Mont Mussy (01) Samedi 6 mai: Prémanon (39) Samedi 13 mai: Mont Mourex (01) Samedi 20 mai: Prévondavaux (VD) Samedi 10 juin: Chancy/Valleiry (74) Samedi 17 juin: Trélex - Finale (VD) Ces courses sont ouvertes à tous, quel que soit le niveau, du débutant au sportif confirmé, en famille ou en individuel. Les inscriptions sur un des 5 parcours proposés se font sur place le jour de l...

Resting sympathetic activity is associated with the sympathetically mediated component of energy expenditure following a meal.

Science.gov (United States)

Limberg, Jacqueline K; Malterer, Katherine R; Matzek, Luke J; Levine, James A; Charkoudian, Nisha; Miles, John M; Joyner, Michael J; Curry, Timothy B

2017-08-01

Individuals with high plasma norepinephrine (NE) levels at rest have a smaller reduction in resting energy expenditure (REE) following β -adrenergic blockade. If this finding extends to the response to a meal, it could have important implications for the role of the sympathetic nervous system in energy balance and weight gain. We hypothesized high muscle sympathetic nerve activity (MSNA) would be associated with a low sympathetically mediated component of energy expenditure following a meal. Fourteen young, healthy adults completed two visits randomized to continuous saline (control) or intravenous propranolol to achieve systemic β -adrenergic blockade. Muscle sympathetic nerve activity and REE were measured (indirect calorimetry) followed by a liquid mixed meal (Ensure). Measures of energy expenditure continued every 30 min for 5 h after the meal and are reported as an area under the curve (AUC). Sympathetic support of energy expenditure was calculated as the difference between the AUC during saline and β -blockade (AUC P ropranolol -AUC S aline , β -REE) and as a percent (%) of control (AUC P ropranolol ÷AUC S aline  × 100). β -REE was associated with baseline sympathetic activity, such that individuals with high resting MSNA (bursts/100 heart beats) and plasma NE had the greatest sympathetically mediated component of energy expenditure following a meal (MSNA: β -REE R  =   -0.58, P =  0.03; %REE R  = -0.56, P =  0.04; NE: β -REE R  = -0.55, P  = 0.0535; %REE R  = -0.54, P  = 0.0552). Contrary to our hypothesis, high resting sympathetic activity is associated with a greater sympathetically mediated component of energy expenditure following a liquid meal. These findings may have implications for weight maintenance in individuals with varying resting sympathetic activity. © 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

High-speed spectral domain optical coherence tomography using non-uniform fast Fourier transform

Science.gov (United States)

Chan, Kenny K. H.; Tang, Shuo

2010-01-01

The useful imaging range in spectral domain optical coherence tomography (SD-OCT) is often limited by the depth dependent sensitivity fall-off. Processing SD-OCT data with the non-uniform fast Fourier transform (NFFT) can improve the sensitivity fall-off at maximum depth by greater than 5dB concurrently with a 30 fold decrease in processing time compared to the fast Fourier transform with cubic spline interpolation method. NFFT can also improve local signal to noise ratio (SNR) and reduce image artifacts introduced in post-processing. Combined with parallel processing, NFFT is shown to have the ability to process up to 90k A-lines per second. High-speed SD-OCT imaging is demonstrated at camera-limited 100 frames per second on an ex-vivo squid eye. PMID:21258551

Internal friction in Al alloys after neutron irradiation at low temperature

International Nuclear Information System (INIS)

Takamura, S.; Kobiyama, M.

1985-01-01

Internal friction and elastic modulus of dilute Al alloys have been measured after fast neutron irradiation at about 5 K. The internal friction spectra in Al-Pb, Al-Si, Al-Zn, Al-Ag, Al-Sn and Al-In are very similar. This result suggests that the configuration of the interstitial-solute atom complex in these alloys is very similar. In Al-Mg, the main complexes have the configuration with nearly symmetry, but its internal friction spectrum is different from that of the above-mentioned alloys. The internal friction spectra and their annealing behavior in Al-Be, Al-Mn, Al-Fe and Al-Cu demonstrate that the configuration of their interstitial-solute atom complex seems to be different from each other and the main complex in these alloys is immobile until stage III. (author)

LA REPRESENTACIÓN DE LA IDENTIDAD INDIVIDUAL EN LA NARRATIVA MEXICANA DE LOS ALBORES DEL SIGLO XXI

Directory of Open Access Journals (Sweden)

LILIA LETICIA GARCĺA PEÑA

2010-11-01

Full Text Available This work analyzes the transformations that exist in the representation of the individual identity in the Mexican narrative works published between 1995 and 2010 by the writers: Guillermo Fadanelli, Carlos Fuentes, Patricia Laurent Kullick, Héctor Manjarrez, Eduardo Antonio Parra, Aline Pettersson, Pedro Ángel Palou, Xavier Velasco y Socorro Venegas. The article has a general perception with the aim of emphasizing, from the individual poetics, the process of symbolization of the “I” in the Mexican narrative from the beginnings of the 21st century, that as cultural phenomenon unfolds in the borders of literariness and society. The theoretical perspective that encourages the analysis starts off, mainly, from the proposal of the North American psychologist Kenneth Gergen, the sociologist Zigmunt Bauman and the mythocritic proposal of Gilbert Durand.

Solidification processing of monotectic alloy matrix composites

Science.gov (United States)

Frier, Nancy L.; Shiohara, Yuh; Russell, Kenneth C.

1989-01-01

Directionally solidified aluminum-indium alloys of the monotectic composition were found to form an in situ rod composite which obeys a lambda exp 2 R = constant relation. The experimental data shows good agreement with previously reported results. A theoretical boundary between cellular and dendritic growth conditions was derived and compared with experiments. The unique wetting characteristics of the monotectic alloys can be utilized to tailor the interface structure in metal matrix composites. Metal matrix composites with monotectic and hypermonotectic Al-In matrices were made by pressure infiltration, remelted and directionally solidified to observe the wetting characteristics of the alloys as well as the effect on structure of solidification in the constrained field of the fiber interstices. Models for monotectic growth are modified to take into account solidification in these constrained fields.

Origin of groundwater salinity in the Sandspruit catchment, Berg River basin (South Africa)

CSIR Research Space (South Africa)

Demlie, M

2011-09-01

Full Text Available . S tation S amplingample?location Water Altitude DTW WL E C ? TDS ? Temp DO E h? TAL ID Date Latitude Longitude source (m.?ams l) (m.?bgl) (m.?ams l) (?s /cm) (ppm) ?(oC ) pH (ppm) (mv) S alinity mg/l S DC 66 22/05/10 ?33.21682 18.7198 GW 205 2775 1387 21....97 6.77 7.72 12.3 1.44 S DC 67 23/05/10 ?33.20024 18.8681 GW 61 21050 10520 21.36 6.81 4.36 15.1 12.65 427 S DC 68 23/05/10 ?33.20432 18.8709 GW 73 5.21 67.79 12290 6142 22.4 6.69 1.12 24.9 7.04 356 S DC 69 23/05/10 ?33.19875 18.8653 GW 69 1.2 67...

Use of an optical digital reader for establishing criterion of quality control in clinical beams; Uso de un lector optico digital (scanner) para establecer criterios de control de calidad en haces clinicos

Energy Technology Data Exchange (ETDEWEB)

Genis S, R. [Unidad de Radioterapia, Hospital Medica Sur, S.A. Pte. de Piedra 150, Col. Toriello Guerra, 14050 Mexico D.F. (Mexico)

1998-12-31

The goal of this work is to present a procedure for realizing the control of the clinical radiation fields through typical radiographic film of verification in radiotherapy and showing the results of the analysis carried out in the expositions of reference fields for photons and electrons using an optical digital reader of high resolution (600 x 1200 dpi) named scanner and a computer program for images edition. It was possible to obtain the quantification of the following parameters: alinement of the radiation beam with the luminous beam, homogeneity or levelling of the radiation field, and self symmetry with respect to the center of the luminous field. With the purpose to compare the results versus an usual method it was realized measurements of the same images with a luminous photo densitometer with 1 mm collimation window. (Author)

Use of Ionizing Radiation by the students of the Faculty of Odontology of the Universidad de San Carlos de Guatemala. Radiographic Techniques evaluation

International Nuclear Information System (INIS)

Ramirez Montenegro, E.S. del

2000-01-01

In the present thesis an evaluation of the radiographic techniques was made by the students in the clinics of the Faculty of Odontology in the Universidad de San Carlos. The sample was 56 students of fourth and fifth year, an survey form was designed including information about radiographic technique, pacient, film seting up, cone alineation, furthermore exposure repetitions and its cause. It was conclude that paralelism technique is used by 46% of the students, 41% bicectriz technique, 13% both techniques, 100 % aleta mordible. Regarding to equipment set up previous to exposure 88% of the students sets the equipment in acceptable way, 88% used XCP accesory to hold the film without desinfection procedures and it was not set up properly. A 92% of the evaluated student had to repeat the exposures due to wrong application of radiographic techniques

Model studies of crosswind landing-gear configurations for STOL aircraft

Science.gov (United States)

Stubbs, S. M.; Byrdsong, T. A.

1973-01-01

A dynamic model was used to directly compare four different crosswind landing gear mechanisms. The model was landed as a free body onto a laterally sloping runway used to simulate a crosswind side force. A radio control system was used for steering to oppose the side force as the model rolled to a stop. The configuration in which the landing gears are alined by the pilot and locked in the direction of motion prior to touchdown gave the smoothest runout behavior with the vehicle maintaining its crab angle throughout the landing roll. Nose wheel steering was confirmed to be better than steering with nose and main gears differentially or together. Testing is continuing to obtain quantitative data to establish an experimental data base for validation of an analytical program that will be capable of predicting full scale results.

Learning disabilities: analysis of 69 children

Directory of Open Access Journals (Sweden)

Meister Eduardo Kaehler

2001-01-01

Full Text Available With this article we intend to demonstrate the importance of evaluation and follow up of children with learning disabilities, through a multidisciplinary team. As well as to establish the need of intervention. We evaluate 69 children, from Aline Picheth Public School, in Curitiba, attending first or second grade of elementary school, through general and evolutionary neurological examination, pediatric checklist symptoms, and social, linguistic and psychological (WISC-III, Bender Infantile and WPPSI-figures evaluation. The incidence was higher in boys (84,1%, familiar history of learning disabilities was found in 42%, and writing abnormalities in 56,5%. The most frequent diagnosis was attention deficit and hyperactivity disorder, in 39,1%. With this program, we aimed to reduce the retention taxes and stress the importance of this evaluation, and, if necessary, multidisciplinar intervention in the cases of learning disabilities.

Use of an optical digital reader for establishing criterion of quality control in clinical beams

International Nuclear Information System (INIS)

Genis S, R.

1998-01-01

The goal of this work is to present a procedure for realizing the control of the clinical radiation fields through typical radiographic film of verification in radiotherapy and showing the results of the analysis carried out in the expositions of reference fields for photons and electrons using an optical digital reader of high resolution (600 x 1200 dpi) named scanner and a computer program for images edition. It was possible to obtain the quantification of the following parameters: alinement of the radiation beam with the luminous beam, homogeneity or levelling of the radiation field, and self symmetry with respect to the center of the luminous field. With the purpose to compare the results versus an usual method it was realized measurements of the same images with a luminous photo densitometer with 1 mm collimation window. (Author)

Ethylidene-bridged Flavan-3-ols in red wine and correlation with wine age.

Science.gov (United States)

Drinkine, Jessica; Lopes, Paulo; Kennedy, James A; Teissedre, Pierre-Louis; Saucier, Cedric

2007-07-25

Condensed tannins are responsible for astringency and bitterness and participate in the color stability of red wines. During wine making and aging, they undergo chemical changes including, for example, acetaldehyde-induced polymerization. Following this study, the ethylidene-bridged flavan-3-ols were monitored in different vintage wines made from grapes collected in the same vineyard in three wineries in Bordeaux, Pauillac, and Saint Julien. Flavan-3-ol ethylidene bridges were quantified by wine 2,2'-ethylidenediphloroglucinol (EDP) phloroglucinolysis. This method was based upon the analysis of EDP, a product formed after acid-catalyzed cleavage of wine flavan-3-ols in the presence of excess phloroglucinol. The flavan-3-ol ethylidene bridges were then compared to flavan-3-ol contents (phloroglucinolysis), phenolic contents, and color measurements. Low amounts of flavan-3-ol ethylidene bridges (0.8-2.5 mg L(-1)) were quantified in wines. Flavan-3-ol ethylidene bridges represent less than 4% of flavan-3-ol bonds, but the proportion of these linkages relative to native interflavan bonds increased with wine age. This proportion correlated with pigmented polymers.

18th Stage of the 2004 Tour de France

CERN Multimedia

Relations with the Hosts States Service

2004-01-01

Haute-Savoie / Pays de Gex 23 July 2004 On Friday 23 July 2004, the 18th stage of the Tour de France cycle race will be departing from Annemasse (Haute-Savoie) and heading for Lons-le-Saunier (Jura), passing through Archamps, Saint-Julien-en-Genevois, Collonges, Farges, Saint-Jean-de-Gonville, Thoiry, Sergy, Saint-Genis-Pouilly, Chevry, Gex et Mijoux, inter alia (a detailed itinerary with approximate passage times can be found on http://www.letour.fr/2004/us/index.html). This event is likely to cause numerous disruptions to local traffic, as the roads used by the race will be closed to all vehicles except those bearing the official race insignia: 90 minutes before the first rider comes through; up to 15 minutes after the police vehicle bearing the ' fin de course ' sign has driven through. Furthermore, there will be no access to the centre of Saint-Genis-Pouilly from about 12.30 p.m. to 2.30 p.m. As a result, you are strongly advised to take these difficulties into account when making any car journeys ...

CERN, accelerator of motivation

CERN Multimedia

François Becler

2014-01-01

Have your dreams ever come true? My dream did, when I was lucky enough to be allowed into the world’s largest particle physics laboratory and spend five whole days there.   François, in front of LEP's DELPHI detector, displayed in the LHCb cavern. François was given the opportunity to visit the experiment during his placement at CERN. I’m a pupil in my last year at the Collège Jean-Jacques Rousseau in Saint-Julien-en-Genevois and was on a work experience placement at CERN from 16 to 20 December last year. I’m so happy I was chosen because working alongside physicists and engineers of all nationalities was like a dream come true. The first thing that impressed me was the size of the site, its infrastructures and facilities but also the fact that I was working in a prestigious, world-renowned organisation. I spent lots of time looking at the map and trying to find my way around... CERN's such a massive place ! Th...

Orientation Club

CERN Multimedia

Club d'orientation

2014-01-01

COURSE ORIENTATION Résultats de samedi 10 mai    C’est sur une carte entièrement réactualisée dans les bois de Versoix, que plus de 100 coureurs sont venus participer à la course d’orientation, type longue distance, préparée par des membres du club du CERN. Le terrain plutôt plat nécessitait une orientation à grande vitesse, ce qui a donné les podiums suivants :  Technique long avec 17 postes : 1er Jurg Niggli, O’Jura en 52:48, 2e Beat Muller, COLJ Lausanne-Jorat en 58:02, 3e Christophe Vuitton, CO CERN en 58:19 Technique moyen avec 13 postes : 1er Jean-Bernard Zosso, CO CERN, en 46:05 ; 2e Yves Rousselot, Balise 25 Besançon, en 55:11 ; 3e Laurent Merat, O'Jura, en 55:13 Technique court avec 13 postes : 1er Julien Vuitton, CO CERN en 40:59, 2e Marc Baumgartner, CO CERN en 43:18, 3e Yaelle Mathieu en 51:42 Su...

AAS, growth hormone, and insulin abuse: psychological and neuroendocrine effects

Directory of Open Access Journals (Sweden)

Michael R Graham

2008-06-01

Full Text Available Michael R Graham1, Peter Evans2, Bruce Davies1, Julien S Baker11Health and Exercise Science Research Unit, Faculty of Health Sport and Science, University of Glamorgan, Pontypridd, Wales, United Kingdom; 2Royal Gwent Hospital, Newport, Gwent, United KingdomAbstract: The nontherapeutic use of prescription medicines by individuals involved in sport is increasing. Anabolic-androgenic steroids (AAS are the most widely abused drug. Much of our knowledge of the psychological and physiological effects of human growth hormone (hGH and insulin has been learned from deficiency states. As a consequence of the Internet revolution, previously unobtainable and expensive designer drugs, particularly recombinant human growth hormone (rhGH and insulin, have become freely available at ridiculously discounted prices from countries such as China and are being abused. These drugs have various physiological and psychological effects and medical personnel must become aware that such prescription medicine abuse appears to be used not only for performance and cosmetic reasons, but as a consequence of psychological pre-morbidity.Keywords: AAS, cosmesis, growth hormone, insulin, performance, strength

Don’t call it a closure!

CERN Document Server

Rosaria Marraffino

2015-01-01

During the Laboratory’s annual closure, some members of the personnel joined their families, others seized the chance to travel the world. The Restaurants were closed, the corridors were dark and the heating was turned off in most of the buildings. However, a lot of people spent the Christmas break working on site and the Bulletin would like to dedicate this first article of the new year to them all!   In the CERN Control Centre (CCC), each shift had two people in position to guarantee regular 24/7 service and to intervene in case of need. Gildas Langlois and Rodolphe Maillet, CCC operators from the Beams Department, spent Christmas Eve there and celebrated it with a cake. “I volunteered to work during the holidays in order to allow colleagues to stay with their families,” says Maillet. On New Year’s Eve, it was Julien Pache and Jean-Michel Nonglaton’s turn to spend the night at work. They had a nice dinner with a CCC-made fondue and some desse...

Durand, Guadet e Wagner. L'evoluzione del metodo compositivo tra XIX e XX secolo / Durand, Guadet and Wagner. The evolution of the compositive method between 19th and 20th Century

Directory of Open Access Journals (Sweden)

Andrés Caballero Lobera

2017-01-01

Full Text Available Il XIX secolo fu un’epoca convulsa per quanto riguarda l’evoluzione del pensiero architettonico. In quanto apice del pensiero illuminista del secolo precedente, tale epoca si manifestò nelle forme dell’architettura storica e allo stesso tempo divenne l’immagine della modernità, stabilendo le basi di quel razionalismo, che avrebbe costruito, ai margini della storia, la sua idea di forma. Tre dei maggiori protagonisti di questo sviluppo, sia per quanto riguarda il loro lavoro di architetti, che come insegnanti, furono Jean-Nicolas-Louis Durand, Julien Guadet e Otto Wagner / The 19th century was a time of upheaval in the development of architectonic thinking. As culmination of the enlightened thinking of the previous century it expressed itself through historical form, and as a reflection of modernity, it established the bases for a rationalist-based architecture that would construct its wish for form outside the margins of history. We highlight the teaching work of three professors and architects in the construction of that thinking: Durand, Guadet and Wagner.

A MORTE NA MARATONA: CELEBRAÇÃO DA VIDA

Directory of Open Access Journals (Sweden)

Rui Proença Garcia

2010-01-01

Full Text Available Neste breve ensaio os autores pretendem analisar a Maratona através de um marco teórico próximo da História das Religiões teorizada por Mircea Eliade e Julien Ries. Partem de uma possível ontologia da palavra Maratona, tentando compreender o seu significado na Grécia Antiga e na contemporaneidade. Analisaram a história da Maratona, os discursos de atletas, documentos escritos sobre esta competição desportiva, visionaram várias Maratonas em especial as de Londres e Nova Iorque, tendo concluído que na sua estrutura e nos seus comentários há símbolos religiosos que a aproximam de um ritual sagrado que tenta repetir o mito fundador. Na origem da Maratona está uma morte. Correr a Maratona e sobreviver significa ultrapassar a morte mítica, entrando-se numa condição humana superior, pelo que os concluem que correr ao Maratona o homem celebra a vida.

Fancy a ride?

CERN Multimedia

Anaïs Schaeffer

2014-01-01

This Sunday 7 September, don’t miss your chance to climb into a supercar, one of those exceptional machines that tear up the tracks and that you sometimes hear revving their engines on the motorway. The 2014 supercar experience day, organised by members of CERN, will allow car lovers to go for a ride in style and all for a good cause!   Supercars at the 2013 experience day. Photo: Kevin Mazzilli. If you have always dreamt of sitting in a Ferrari, feeling the vibrations of a Lamborghini, or losing yourself in the hushed calm of a classic car, don’t miss the supercar experience day taking place on Sunday, 7 September! This event has been organised by CERN’s own car enthusiasts, in collaboration with the charity Kumansansa – Children of Zambia, founded by two CERN members. It will take place for the third consecutive year in the car park of the Macumba leisure centre in Saint-Julien-en-Genevois (France). From 9.30 a.m. to 6 p.m., visitors old and young (c...

Orienteering club

CERN Multimedia

Club d'orientation

2011-01-01

Coupe de printemps – 2e étape à Attalens Les cinq parcours répartis dans les bois d’Attalens ont attiré plus d’une centaine de concurrents samedi 26 mars. Les coureurs ont évolué sur un terrain alternant zones rapides et techniques. Les plus habiles dans chaque catégorie ont été les suivants : Facile court (2,4 km – dénivelé de 60 m – 7 postes) : 1er Julien Vuitton (CO CERN) en 19:17 2e Natalja Niggli (O’Jura) en 23:49 3e Victor Dannecker (O’Jura) en 27:12 Facile moyen (3,8 km – dénivelé de 90 m – 12 postes) : 1ere Caroline Mathys (Epalinges) en 40:28 2e Philippe Seixas (Epalinges) en 42:12 3e Sylvie Guex (CO Lausanne-Jorat) en 43:59 Technique court (4,4 km – dénivelé de160 m – 15 postes) : 1er Gaëtan Vuitton (CO CERN) en 38:...

Of data and dust

CERN Multimedia

Stephanie Hills

2016-01-01

The traditional image of an archive is one of dusty old boxes, books and papers. When your archive is digital, dust spells disaster. An innovative environmental sensor designed and built by a CERN IT specialist has become an essential element in the Laboratory’s data-preservation strategy.   The novel air particle monitoring sensor designed by CERN's Julien Leduc. CERN’s archive holds more than 130 petabytes of data from past and present high-energy physics experiments. Some of it is 40 years old, most of it needs to be kept forever, and all of it is held on tape cartridges (over 20,000 of them). The cartridges are held inside tape libraries with robotic arms that load them into tape drives where they can be read and written. Tape cartridges have many advantages over other data storage media, notably cost and long-term reliability, but topping the list of drawbacks is their vulnerability to contamination from airborne dust particles; a tiny piece of g...

Sobre um foco urbano de esquistossomose em área metropolitana da região sudeste do Brasil

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Guimarães Carlos Tito

1993-01-01

Full Text Available Descreve-se foco de transmissão ativa de esquistossomose mansoni em Belo Horizonte, MG, Brasil, localizado no Parque "Julien Rien", uma área de lazer com 48.500 m², criada pela Prefeitura Municipal, em 1980, na zona sul da cidade. Em capturas feitas durante 10 anos (1983-1992 foram coletados 3.361 exemplares de Biomphalaria glabrata (diâmetro médio= 9,3 mm, dos quais 23 (0,7% estavam infectados pelo Schistosoma mansoni. O encontro de moluscos hospedeiros intermediários do S. mansoni em áreas urbanizadas (pequenos lagos artificiais cimentados de parques, jardins, prédios públicos, e outros pode estar relacionado com a introdução de peixes e plantas aquáticas. É sugerida, como medida profilática, a não introdução de peixes e plantas aquáticas nesses locais, a não ser após período de quarentena de, no mínimo, 30 dias.

Lattice defects in ion-implanted aluminium studied by means of perturbed angular correlations. Pt. 1

International Nuclear Information System (INIS)

Pleiter, F.; Prasad, K.G.

1984-01-01

Migration and clustering of lattice defects after implantation of 111 In in Al and subsequent annealing at temperatures in the range from 80 to 800 K were investigated applying the DPAC technique. The effects of implantation dose, implantation temperature, laser irradiation, and plastic deformation were studied. The measurements on plastically deformed Al were complemented by positron lifetime measurements. Four In-defect clusters were observed that can be flagged by well-defined hyperfine interaction parameters, and their symmetry properties were determined by using single-crystal samples. Important conclusions are: (i) monovacancies are not trapped by In-atoms, (ii) small In-defect clusters are formed by direct trapping of divacancies and/or trivacancies, and (iii) extended In-defect clusters are very stable and anneal in the temperature range 600-700 K. Consequences for the interpretation of other measurements on dilute Al(In) alloys are discussed. (Auth.)

Surfactant modified clays’ consistency limits and contact angles

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S Akbulut

2012-07-01

Full Text Available This study was aimed at preparing a surfactant modified clay (SMC and researching the effect of surfactants on clays' contact angles and consistency limits; clay was thus modified by surfactants formodifying their engineering properties. Seven surfactants (trimethylglycine, hydroxyethylcellulose  octyl phenol ethoxylate, linear alkylbenzene sulfonic acid, sodium lauryl ether sulfate, cetyl trimethylammonium chloride and quaternised ethoxylated fatty amine were used as surfactants in this study. The experimental results indicated that SMC consistency limits (liquid and plastic limits changedsignificantly compared to those of natural clay. Plasticity index and liquid limit (PI-LL values representing soil class approached the A-line when zwitterion, nonionic, and anionic surfactant percentageincreased. However, cationic SMC became transformed from CH (high plasticity clay to MH (high plasticity silt class soils, according to the unified soil classification system (USCS. Clay modifiedwith cationic and anionic surfactants gave higher and lower contact angles than natural clay, respectively.

Towards the use of OCT angiography in clinical dermatology

Science.gov (United States)

Baran, Utku; Choi, Woo June; Wang, Ruikang K.

2016-02-01

Optical coherence tomography (OCT) is a popular imaging technique used in ophthalmology, and on the way to become clinically viable alternative in dermatology due to its capability of acquiring histopathology level images of in vivo tissue, noninvasively. In this study, we demonstrate the capabilities of OCT-based angiography (OMAG) in detecting high-resolution, volumetric structural and microvascular features of in vivo human skin with various conditions using a swept source OCT system that operates on a central wavelength of 1310 nm with an A-line rate of 100 kHz. OMAG images provide detailed in vivo visualization of microvasculature of abnormal human skin conditions from face, chest and belly. Moreover, the progress of wound healing on human skin from arm is monitored during longitudinal wound healing process. The presented results promise the clinical use of OCT angiography in treatment of prevalent cutaneous diseases within human skin, in vivo.

Upgrades and expansion of the Cornell High Energy Synchrotron Source (CHESS)

International Nuclear Information System (INIS)

White, Jeffrey A.

2000-01-01

The Cornell High Energy Synchrotron Source (CHESS) is a user-oriented National Facility that provides state-of-the-art synchrotron radiation facilities to scientists worldwide. With major new funding in 1999, we now have 5 ongoing upgrade and expansion projects: 1) a new building addition that will house a new wiggler beamline (CHESS G-line) with three new experimental stations; 2) a new more powerful wiggler source for both A and G beamlines; 3) an upgrade to the A-line optics for better heat load handling and focussing; 4) a rebuild of the F-cave optics room with new optics to handle higher machine current; and 5) a renovation to the user laboratory space surrounding the F1 and F2 crystallography stations. We expect these upgrades and a new G line Cornell faculty collaborating group to raise the level of excitement and productivity at CHESS for many years to come

The first finding of Asian black bear (Carnivora, Ursidae, Ursus (Euarctos) thibetanus G. Cuvier, 1823) in the Late Pleistocene of northern Eurasia.

Science.gov (United States)

Kosintsev, P A; Tiunov, M P; Gimranov, D O; Panov, V S

2016-11-01

An M1 tooth of Asian black bear (Ursus (Euarctos) thibetanus G. Cuvier, 1823) was found in deposits of the Tetyukhinskaya cave (Middle Sikhote-Alin, 44°35'N, 135°36'E). This finding is the first reliable evidence of Asian black bear's presence in Pleistocene of Primorye. Its morphological and morphometric descriptions are given. The period of inhabitation of U. (E.) thibetanus determined based on the radiocarbon date obtained during the study of the tooth, is 39 874 ± 133 BP (NSK-850, UGAMS-21786), which corresponds to the middle of Marine Isotope Stage 3 (MIS 3) of Late Pleistocene. The composition of ancient theriofauna indicates the existence of wide variety of landscapes in Primorye in the middle of Late Pleistocene. A refugium of forest fauna, in which species of taiga, nemoral, and Central Asian mountain-forest theriocomplexes were present, was located in southern Primorye in Late Pleistocene.

Geological nature of mineral licks and the reasons for geophagy among animals

Science.gov (United States)

Panichev, Alexander M.; Popov, Vladimir K.; Chekryzhov, Igor Yu.; Seryodkin, Ivan V.; Sergievich, Alexander A.; Golokhvast, Kirill S.

2017-06-01

In this paper, the reasons for geophagy (the eating of rocks by wild herbivores) in two regions of the eastern Sikhote-Alin volcanic belt are considered. The mineralogical and chemical features of the consumed rocks, as well as the geological conditions of their formation, are investigated. A comparative analysis of the mineral and chemical composition of the consumed rocks and the excrement of the animals, almost completely consisting of mineral substances, is carried out. It is established that the consumed rocks are hydrothermally altered rhyolitic tuffs located in the volcanic calderas and early Cenozoic volcano-tectonic depressions. They consist of 30-65 % from zeolites (mainly clinoptilolites) and smectites, possessing powerful sorption properties. According to the obtained data, the main reason for geophagy may be connected with the animals' urge to discard excessive and toxic concentrations of certain elements that are widespread in specific habitats and ingested with forage plants.

Renal thrombotic microangiopathy caused by interferon beta-1a treatment for multiple sclerosis

Directory of Open Access Journals (Sweden)

Mahe J

2013-08-01

Full Text Available Julien Mahe,1 Aurélie Meurette,2 Anne Moreau,3 Caroline Vercel,2 Pascale Jolliet1,4 1Clinical Pharmacology Department, Institute of Biology, University Hospital, Nantes, France; 2Clinical Nephrology and Immunology Department, University Hospital, Nantes, France; 3Laboratory of Pathology, University Hospital, Nantes, France; 4EA 4275 Biostatistics, Pharmacoepidemiology and Subjective Measures in Health Sciences, University of Nantes, Nantes, France Abstract: Interferon beta-1a is available as an immunomodulating agent for relapsing forms of multiple sclerosis. Common side effects include flu-like symptoms, asthenia, anorexia, and administration site reaction. Kidney disorders are rarely reported. In this study we describe the case of a woman who has been undergoing treatment with interferon beta-1a for multiple sclerosis for 5 years. She developed a hemolytic-uremic syndrome with intravascular hemolysis in a context of severe hypertension. A kidney biopsy showed a thrombotic microangiopathy. This observation highlights an uncommon side effect of long-term interferon beta-1a therapy. Pathophysiological mechanisms leading to this complication might be explained by the antiangiogenic activity of interferon. Keywords: thrombotic microangiopathy, interferon beta, hemolytic-uremic syndrome, antiangiogenic activity

Subcritical saturation of the magnetorotational instability through mean magnetic field generation

Science.gov (United States)

Xie, Jin-Han; Julien, Keith; Knobloch, Edgar

2018-03-01

The magnetorotational instability is widely believed to be responsible for outward angular momentum transport in astrophysical accretion discs. The efficiency of this transport depends on the amplitude of this instability in the saturated state. We employ an asymptotic expansion based on an explicit, astrophysically motivated time-scale separation between the orbital period, Alfvén crossing time and viscous or resistive dissipation time-scales, originally proposed by Knobloch and Julien, to formulate a semi-analytical description of the saturated state in an incompressible disc. In our approach a Keplerian shear flow is maintained by the central mass but the instability saturates via the generation of a mean vertical magnetic field. The theory assumes that the time-averaged angular momentum flux and the radial magnetic flux are constant and determines both self-consistently. The results predict that, depending on parameters, steady saturation may be supercritical or subcritical, and in the latter case that the upper (lower) solution branch is always stable (unstable). The angular momentum flux is always outward, consistent with the presence of accretion, and for fixed wavenumber peaks in the subcritical regime. The limit of infinite Reynolds number at large but finite magnetic Reynolds number is also discussed.

CERN Multimedia

2014-01-01

Samedi 5 avril, les organisateurs du Club d’orientation du CERN ont accueilli au Mont Mourex une petite centaine de participants qui ont pu découvrir de beaux parcours techniques, assez physiques sur un terrain sec. Les podiums pour les divers circuits sont les suivants : Technique long avec 17 postes : 1er Andreas Grote, (Fribourg) en 50:26, 2e Christophe Vuitton en 51:47 et 3e Berni Wehrle en 59:37. Technique moyen avec 14 postes : 1er Sverre Berg Lutnaes, CO CERN en 46:05, 2e Bruno Barge en 46:44, et 3e exequo Marie Vuitton / Patrick Rousseau en 46:55 (A noter que ces 4 concurrents sont tous sous la même minute). Technique court avec 10 postes : 1er Julien Vuitton, CO CERN en 22:27 devançant haut la main ces adversaires, 2e Amandine Marion en 42:03, 3e Dominique Balay en 47:49. Facile moyen avec 13 postes : 1er Konstantinos Haider, CO CERN en 44:30, 2e Céline Zosso en 46:04, 3e Tessa, Ralf Nardini en 47:51. Facile cout avec 10 postes : 1er C&ea...

The Narrativization of an Unusual Event at the Belgrade Zoo: A Semiotic Analysis of The Story of Gabi the Dog and the Jaguar

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Sonja Žakula

2016-02-01

Full Text Available The paper offers a semiotic analysis of the narrative of Gabi the dog and the jaguar in the form in which the story appears on the website of the Belgrade zoo. I believe that it is valid to assume that an analysis of this narrative can provide a window into the ways in which meanings of concepts such as ‘wildness’, ‘domesticity’, ‘freedom’, ‘captivity’ and ultimately, ‘nature’ and ‘culture’ are articulated within the context of this institution. On the one hand, I will base the paper on ideas articulated in the field of human-animal relations, and on the other on the methodological postulates of semiotic analysis introduced by Algirdas Julien Greimas and further developed by Dragana Antonijević. The aim of the paper is to, by applying semiotic analysis to the way in which an unusual event at the zoo was narrativized, uncover the deeper structure of thought which underlies the story and reflects and shapes not just the discourse of the Belgrade zoo, but the implicit understanding of the role and function of zoos in Serbia up until the present day.

Orienteering club

CERN Multimedia

Club d'orientation

2014-01-01

Course d'orientation C’est sous un beau soleil samedi 4 octobre que s’est déroulée la 6e étape de la Coupe genevoise d’automne organisée par le club. Plus d’une centaine de concurrents provenant de 7 clubs de CO avaient fait le déplacement pour courir sur un des cinq parcours proposés dans les bois de Trélex-Génolier (VD). Le podium est le suivant : Technique long (5,9 km, 19 postes) : 1er Jurg Niggli, O’Jura (1:00:02); 2e Berni Wehrle, CO CERN (1:06:44); 3e Konrad Ehrbar, COLJ (1:07:08) Technique moyen (4,8 km, 18 postes) : 1er Christophe Vuitton, CO CERN (54:25); 2e J.B. Zosso, CO CERN (1:01:19); 3e Jeremy Wichoud, COLJ (1:06:21) Technique court (3,8 km, 14 postes) : 1er Julien Vuitton, CO CERN (36:19); 2e Vladimir Kuznetsov, COLJ (48:47); 3e Natalia Niggli, O’Jura (50:38) Facile moyen (3,2 km, 11 postes) : 1ère Alina Niggli, O&...

Orienteering club

CERN Multimedia

Club d'orientation

2011-01-01

Coupe de printemps - les épreuves s’enchainent Le Club du CERN organisait la 4e étape de la coupe Genevoise de printemps samedi 9 avril. Tout était au rendez-vous pour une belle épreuve : soleil et nouvelle carte dans la forêt de Pougny-Challex. Les podiums des 5 parcours sont les suivants :   Facile court (2 km – 8 postes) : 1er Lucine Gintzburger en 29:01 - 2e Maria & Adèle Rapseviciute en 41:34 - 3e Emanuelle Alves en 41 :40. Facile moyen (2,9 km – 9 postes) : 1ere Konstantinos Haider (CO CERN) en 26:01 - 2e Joho en 34:41 - 3e Odysseas Willians/Jan Bleesz en 38:43. Technique court (3,2 km – 8 postes) : 1er Elisabeth Geneux en 32:08 - 2e Dominique Balay (CO CERN) en 33:59 - 3e Yves Meynet en 35:18. Technique moyen (4,9 km – 10 postes) : 1er Pierre-Yves Meyer en 47:04 - 2e Julien Nicolet en 50:06 - 3e Jean-Pierre Poncet en 50:42. Technique long (6,6 km &a...

Application of simulation technique on debris flow hazard zone delineation: a case study in the Daniao tribe, Eastern Taiwan

Directory of Open Access Journals (Sweden)

M. P. Tsai

2011-11-01

Full Text Available Typhoon Morakot struck Taiwan in August 2009 and induced considerable disasters, including large-scale landslides and debris flows. One of these debris flows was experienced by the Daniao tribe in Taitung, Eastern Taiwan. The volume was in excess of 500 000 m³, which was substantially larger than the original design mitigation capacity. This study considered large-scale debris flow simulations in various volumes at the same area by using the DEBRIS-2D numerical program. The program uses the generalized Julien and Lan (1991 rheological model to simulate debris flows. In this paper, the sensitivity factor considered on the debris flow spreading is the amount of the debris flow initial volume. These simulated results in various amounts of debris flow initial volume demonstrated that maximal depths of debris flows were almost deposited in the same area, and also revealed that a 20% variation in estimating the amount of total volume at this particular site results in a 2.75% variation on the final front position. Because of the limited watershed terrain, the hazard zones of debris flows were not expanded. Therefore, the amount of the debris flow initial volume was not sensitive.

Mechanical pressure and momentum conservation in dry active matter

Science.gov (United States)

Fily, Y.; Kafri, Y.; Solon, A. P.; Tailleur, J.; Turner, A.

2018-01-01

We relate the breakdown of equations of states (EOS) for the mechanical pressure of generic dry active systems to the lack of momentum conservation in such systems. We show how net sources and sinks of momentum arise generically close to confining walls. These typically depend on the interactions of the container with the particles, which makes the mechanical pressure a container-dependent quantity. We show that an EOS is recovered if the dynamics of the propulsive forces of the particles are decoupled from other degrees of freedom and lead to an apolar bulk steady-state. This recovery of an EOS stems from the mean steady-state active force density being the divergence of the flux of ‘active impulse’, an observable which measures the mean momentum particles will receive from the substrate in the future. ), which features invited work from the best early-career researchers working within the scope of J. Phys. A. This project is part of the Journal of Physics series’ 50th anniversary celebrations in 2017. Julien Tailleur was selected by the Editorial Board of J. Phys. A as an Emerging Talent.

Orienteering Club

CERN Multimedia

Club d'Orientation

2011-01-01

C’est reparti pour une nouvelle coupe d’automne Samedi 27 août, plus de soixante coureurs sont venus au rendez-vous de la première étape de la coupe dans la forêt de Grange Malval. Certains rentraient juste de la grande semaine O’Festival de Chambéry, courses en parallèle des championnats du monde de CO, et ne manquaient pas d’entrainement. Les 6 parcours proposés par les organisateurs du club de CO du CERN ont été remportés par: Facile court (1,7 km, dénivelé 50 m, 10 postes) 1er Melissa Assfalo (19:23), 2e Elliot Dannecker (26:44), 3e Ulysse Dannecker (26:51) Facile moyen (2,7 km, dénivelé 80 m, 13 postes) 1er Julien Vuitton (22:28), 2e Carlos Vidal (49:04), 3e Clément Genot (1:03:20) Facile long (3,9 km, dénivelé 100 m, 10 postes) 1er Tony/Joan Cass/Brooks (1:23:30), 2e Anna Lip...

Urgent need of a doctor

CERN Multimedia

2003-01-01

GENEVE PATIENT NOT FIT TO BE MOVED: Call your family doctor Or: SOS MEDECINS (24H/24H) 022 748-49-50 Or: ASSOC. MEDECINS DE GENEVE (07H-23H) 022 322-20-20 PATIENT CAN BE MOVED: • HOPITAL CANTONAL 24 Micheli du Crest 022 372-33-11 / 022 382-33-11 URGENCES PEDIATRIQUES 30 Bd de la Cluse 022 382-45-55 MATERNITY 24 Micheli du Crest 022 382-68-16 / 022 382-33-11 CLINIQUE OPHTALMOLOGIQUE 22 Alcide Jentzer 022 382-84-00 • HOPITAL DE LA TOUR Meyrin 022 719-61-11 EMERGENCIES ADULTES Meyrin 022 719-66-80 EMERGENCIES: AMBULANCES (GENEVE AND VAUD) 144 FIRE BRIGADE CERN 022 767-44-44 FIRE BRIGADE 118 POLICE 117 CENTRE ANTI-POISON (24H/24H): 01-251-51-51 EUROPEAN EMERGENCY CALL: 112 FRANCE PATIENT NOT FIT TO BE MOVED: Call your family doctor (or 15) PATIENT CAN BE MOVED: • HOPITAL DE ST. JULIEN rue Amédée VIII de Savoie 04-50-49-65-65 EMERGENCIES rue Amédée VIII de Savoie 04-50-49-65-83 MATERNITY r...

Urgent Need of a Doctor outside of CERN

CERN Document Server

2004-01-01

GENEVA PATIENT NOT FIT TO BE MOVED: Call your family doctor Or: SOS MEDECINS (24H/24H) 022 748-49-50 Or: ASSOC. MEDECINS DE GENEVE (07H-23H) 022 322-20-20 PATIENT CAN BE MOVED: • HOPITAL CANTONAL 24 Micheli du Crest 022 372-33-11 / 022 382-33-11 PAEDIATRIC EMERGENCIES 30 Bd de la Cluse 022 382-45-55 MATERNITY 24 Micheli du Crest 022 382-68-16 / 022 382-33-11 CLINIQUE OPHTALMOLOGY 22 Alcide Jentzer 022 382-84-00 • HOPITAL DE LA TOUR Meyrin 022 719-61-11 EMERGENCIES ADULTS Meyrin 022 719-66-80 EMERGENCIES: AMBULANCE (GENEVE AND VAUD) 144 FIRE BRIGADE 118 POLICE 117 ANTI POISON CENTRE (24H/24H) 01-251-51-51 EUROPEAN EMERGENCY CALL  112 REMINDER: For all accidents, incidents, emergencies etc. ON CERN PREMISES: FIRE BRIGADE CERN 022 767-44-44 FRANCE PATIENT NOT FIT TO BE MOVED: Call your family doctor (or 15) PATIENT CAN BE MOVED: • HOPITAL DE ST. JULIEN Rue Amédée VIII de Savoie 04-50-49-65-65 EMERG...

Urgent Need of a Doctor

CERN Multimedia

2004-01-01

GENEVE PATIENT NOT FIT TO BE MOVED: Call your family doctor Or: SOS MEDECINS (24H/24H) 022 748-49-50 Or: ASSOC. MEDECINS DE GENEVE (07H-23H) 022 322-20-20 PATIENT CAN BE MOVED: • HOPITAL CANTONAL 24 Micheli du Crest 022 372-33-11 / 022 382-33-11 PAEDIATRIC EMERGENCIES 30 Bd de la Cluse 022 382-45-55 MATERNITY 24 Micheli du Crest 022 382-68-16 / 022 382-33-11 CLINIQUE OPHTALMOLOGY 22 Alcide Jentzer 022 382-84-00 • HOPITAL DE LA TOUR Meyrin 022 719-61-11 EMERGENCIES ADULTS Meyrin 022 719-66-80 EMERGENCIES: AMBULANCE (GENEVE AND VAUD) 144 FIRE BRIGADE 118 FIRE BRIGADE CERN 022 767-44-44 POLICE 117 ANTI POISON CENTRE (24H/24H) 01-251-51-51 EUROPEAN EMERGENCY CALL  112 FRANCE PATIENT NOT FIT TO BE MOVED: Call your family doctor (or 15) PATIENT CAN BE MOVED: • HOPITAL DE ST. JULIEN Rue Amédée VIII de Savoie 04-50-49-65-65 EMERGENCIES Rue Amédée VIII de Savoie 04.50-49-65-83 MATERNITY Rue Am&...

Urgent Need of a Doctor

CERN Multimedia

2004-01-01

GENEVE PATIENT NOT FIT TO BE MOVED: Call your family doctor Or: SOS MEDECINS (24H/24H) 022 748-49-50 Or: ASSOC. MEDECINS DE GENEVE (07H-23H) 022 322-20-20 PATIENT CAN BE MOVED: • HOPITAL CANTONAL 24 Micheli du Crest 022 372-33-11 / 022 382-33-11 PAEDIATRIC EMERGENCIES 30 Bd de la Cluse 022 382-45-55 MATERNITY 24 Micheli du Crest 022 382-68-16 / 022 382-33-11 CLINIQUE OPHTALMOLOGY 22 Alcide Jentzer 022 382-84-00 • HOPITAL DE LA TOUR Meyrin 022 719-61-11 EMERGENCIES ADULTS Meyrin 022 719-66-80 EMERGENCIES: AMBULANCE (GENEVE AND VAUD) 144 FIRE BRIGADE 118 FIRE BRIGADE CERN 022 767-44-44 POLICE 117 ANTI POISON CENTRE (24H/24H) 01-251-51-51 EUROPEAN EMERGENCY CALL  112 FRANCE PATIENT NOT FIT TO BE MOVED: Call your family doctor (or 15) PATIENT CAN BE MOVED: • HOPITAL DE ST. JULIEN Rue Amédée VIII de Savoie 04-50-49-65-65 EMERGENCIES Rue Amédée VIII de Savoie 04.50-49-65-83 MATERNITY Rue Am...

First evidence of the pore-forming properties of a keratin from skin mucus of rainbow trout (Oncorhynchus mykiss, formerly Salmo gairdneri).

Science.gov (United States)

Molle, Virginie; Campagna, Sylvie; Bessin, Yannick; Ebran, Nathalie; Saint, Nathalie; Molle, Gérard

2008-04-01

The epidermis of fish is covered with a layer of mucus, which contributes to the defence of the species against parasites, bacteria and fungi. We have previously extracted glycoproteins from various mucus samples from fish and have shown that they present pore-forming activities well correlated with strong antibacterial properties [Ebran, Julien, Orange, Saglio, Lemaitre and Molle(2000) Biochim. Biophys. Acta 1467, 271-280]. The present study focuses on the 65 kDa glycoprotein, Tr65, from the rainbow trout (Oncorhynchus mykiss, formerly Salmo gairdneri).Enzymatic digestion of Tr65 yielded a fragment pattern with strong homology with that of trout type II cytokeratin. Sequence analysis of the cDNA clone obtained by PCR confirmed this homology. We thus constructed a plasmid to overproduce the recombinant Tr65. We extracted and purified this recombinant Tr65, using it for multichannel and single-channel experiments in azolectin bilayers. Our results with recombinant Tr65 confirmed the pore-forming properties already shown with native antibacterial Tr65. These findings offer new insights into the function of keratin proteins present in various mucosal surfaces of animals and human beings.

Agronomical Parameters, Sugar Profile and Antioxidant Compounds of “Catherine” Peach Cultivar Influenced by Different Plum Rootstocks

Directory of Open Access Journals (Sweden)

Carolina Font i Forcada

2014-02-01

Full Text Available The influence of seven plum rootstocks (Adesoto, Monpol, Montizo, Puebla de Soto 67 AD, PM 105 AD, St. Julien GF 655/2 and Constantí 1 on individual and total sugars, as well as on antioxidant content in fruit flesh of “Catherine” peaches, was evaluated for three years. Agronomical and basic fruit quality parameters were also determined. At twelve years after budding, significant differences were found between rootstocks for the different agronomic and fruit quality traits evaluated. The Pollizo plum rootstocks Adesoto and PM 105 AD seem to induce higher sweetness to peach fruits, based on soluble solids content, individual (sucrose, fructose and sorbitol and total sugars. A clear tendency was also observed with the rootstock Adesoto, inducing the highest content of phenolics, flavonoids, vitamin C and relative antioxidant capacity (RAC. Thus, the results of this study demonstrate the significant effect of rootstock on the sugar profile and phytochemical characteristics of peach fruits. In addition, this work shows the importance of the sugar profile, because specific sugars play an important role in peach flavour quality, as well as the studied phytochemical compounds when looking for high quality peaches with enhanced health properties.

Soils of the Eastern mountainsides of the southern Sikhote-Alin (on the example of Lazovsky nature reserve, Russia)

Science.gov (United States)

Tregubova, Valentina; Semal, Victoria; Nesterova, Olga; Yaroslavtsev, Alexis

2017-04-01

The most common soils of the southern Far East are Brownzems under Russian classification (Cambisols), which are the zonal ones, emerging on the steep slopes and tops of hills, on high river terraces under broad-leaved and cedar-broad-leaved forests. Those soils formed due to two processes: organic matter metamorphism and clayization by siallite, leading to the formation of clay-metamorphic horizon Bw. The main morphological features of Cambisols are not deep soil profile (50 - 70 cm), weak horizons differentiation, with lots of cobble. Chemically those soils are low saturated, even in the humus horizon. Distribution of total absorbed bases is mostly accumulative, which is related to the distribution of humus in these soils, and the predominant type of clay fraction distribution of. The only exception are Humic Cambisols and Humic Cambisols Calcic which were formed on redeposited products of limestone rock weathering. Fine-grained deposits are mainly loams with a low content of silt. Silt distribution has an accumulative character with a gradual decrease in the content of silt down from the top of the profile. Layer of fresh leaf fall is very common for the Humic Cambisols surfaces, and under it there is the litter of plant residues with different degrees of decomposition. Accumulative humus horizon is dark gray with brownish tint, thin, from 10 to 15 cm in depth, loose, crumbly, highly penetrated by roots, with a strong granular structure, with aggregates tightly attached to the root hairs, sandy loam or sandy clay loam. The middle horizon is brown, yellowish-brown, divided into sub-horizons, with different color intensity, density, soil texture and amount of cobble. Dystric Cambisols are acidic or strongly acidic with low saturation of soil absorbing complex. Due to amount and distribution of organic matter these soils can be divided into two groups. The first group is soils with accumulative humus distribution: with a low depth humus-accumulative horizon (11 - 12 cm) and high content of organic matter (23 - 26 %); humus in the upper horizons mainly consists of humic acids, while in lower horizons it is with higher ratio of fulvic acids. The second group is soils with a gradual humus distribution along the profile and with a smaller amount of organic matter in the upper horizon (9 - 13 %) and with no differentiation in humus composition. Folic Cambisols are formed on the watershed surfaces, on the steep slopes under pine and oak trees. Under thin litter horizon these soils have organic-accumulative horizon of well decomposed organic matter, but in contrast with Dystric Cambisols it doesn't have strong granular structure. At the bottom the organic horizon is humic-impregnated or has clear streaks of humus. Humic Cambisols are formed in the lower parts of slopes, on steep slopes and high river terraces under pine and deciduous forests. All this soils have humified litter horizon, which is up to 7 cm in depth, weak differentiation of the soil profile, deep humus-accumulative horizon (18 - 31 cm) with dark gray, almost black color, with strong granular structure and loam or clay loam texture. Soil acidity is determined by the lithogenic basis. Base saturation is quite high (77 - 90%) in mineral horizons and is up to 70 % in organic and accumulative ones. There is a high amount of humus on the entire profile (5 - 16 %), which consists of humic acids in the upper half of the profile and of fulvates at the bottom. Humic Cambisols Gleyic are located in the lower parts of gentle slopes under mixed forest. Due to higher moisture at the lower parts of slopes this soils have signs of weak gley process in dense subsoil horizons in the form of small light grey spots. Humic Leptosols are weakly developed soils formed on rocky hills, boulders, rocky outcrops, under thick moss layer, under which is a layer of weathered gravel rock. Humic Cambisols (Calcic) are formed on the surface sediments of limestone. They have a deep soil profile, up to 40 cm and it's humus-accumulative horizon is dark gray or black, gradually passing into soil-forming rock. Bw horizon, typical for Cambisols, is weak.

Cerebral state index during propofol anesthesia : A Comparison with the Bispectral Index and the A-Line ARX Index

NARCIS (Netherlands)

Jensen, EW; Litvan, H; Revuelta, M; Rodriguez, BE; Caminal, P; Martinez, P; Vereecke, H; Struys, Michel MRF

Background: The objective of this study was to prospectively test the Cerebral State Index designed for measuring the depth of anesthesia. The Cerebral State Index is calculated using a fuzzy logic combination of four subparameters of the electroencephalographic signal. The performance of the

Ocean Acidification of the Pacific Northwest Coastal Waters: A Modeling Study

Science.gov (United States)

Siedlecki, S. A.; MacCready, P.; McCabe, R. M.; Feely, R. A.; Alin, S. R.; Newton, J.; Barth, J. A.; Durski, S. M.

2016-02-01

Total inorganic carbon and alkalinity is incorporated into a regional bio-physical model to examine inorganic carbon variability along the Washington and Oregon continental margin. Results are compared to output from an existing oxygen model (Siedlecki et al., 2015) combined with observationally-based empirical relationships between carbon system parameters, oxygen, and temperature (Alin et al., in prep). Model hindcasts for 2007 and 2013 are also validated against local observations of dissolved oxygen, pH, and the saturation state of aragonite. Challenges and benefits of each approach are discussed. The model suggests that the volume of hypoxic and undersaturated water present over the continental shelf increases over the upwelling season, occupying more of the water column later in the upwelling season. This would result in increasingly stressful conditions for biota over most of the water column as the upwelling season progresses. Spatial variability in the volume of undersaturated water in the region will also be discussed.

Ocean Acidification of the coastal waters of the Pacific Northwest: A modeling study

Science.gov (United States)

Siedlecki, S. A.; Hermann, A. J.; Bond, N. A.; Alin, S. R.; Feely, R. A.; Hales, B. R.; Newton, J.; Migliaccio, L.

2013-12-01

A regional oxygen model of the Washington and Oregon shelves (Siedlecki, S.A., Banas, N., Davis, K.A., Giddings, S., P. MacCready, Connolly, T., & B. Hickey. Seasonal Oxygen variability on the continental shelves of Washington and Oregon, in prep) is combined with the empirical relationships between the carbonate system, oxygen and temperature (Alin et al, in prep) to simulate the carbonate chemistry in this region. A model hindcast for 2009 is compared to local observations of oxygen, and aragonite saturation. The model is able to reproduce the seasonal change in oxygen observed on the Oregon shelf. Challenges of this approach are discussed. The volume of hypoxic and undersaturated water increases over the upwelling season, occupying more of the water column later in the upwelling season. This results in increasingly stressful conditions over most of the water column for biota on the shelf as the upwelling season progresses. How the rate of ascension and presence of this undersaturated water varies regionally will be discussed.

NRC [Nuclear Regulatory Commission] editorial style guide

International Nuclear Information System (INIS)

Beeson, J.F.; Calure, B.A.; Gable, D.; Lesar, M.T.; Mejac, M.F.; Sanders, R.F.

1989-10-01

Editorial style refers to the choices that writers, editors, and secretaries make to eliminate inconsistencies in their documents. These choices apply to the recurrent features of a document such as abbreviations, capitalization, compound words, numbers, symbols, and punctuation, as well as to references and footnotes. Making these choices is sometimes difficult because usage changes as the language evolves. Consider the use of hyphens, for example. Do we write non-power reactor or nonpower reactor? Is it on-site incident or onsite incident? Although usage is moving away from the use of hyphens with prefixes, the authorities who compile style guides do not always agree about which choice to use at a given time. Moreover, each discipline -- law, physics, mathematics -- has specific standards that apply to the publications for that discipline. Even in an area as seemingly certain as spelling, overlapping usage exists. Reputable dictionaries show both ''align'' and ''aline'' as correct spellings. Likewise, ''disc, disk, and diskette'' currently coexist as equally valid choices

Heartbeat OCT: in vivo intravascular megahertz-optical coherence tomography

Science.gov (United States)

Wang, Tianshi; Pfeiffer, Tom; Regar, Evelyn; Wieser, Wolfgang; van Beusekom, Heleen; Lancee, Charles T.; Springeling, Geert; Krabbendam, Ilona; van der Steen, Antonius F.W.; Huber, Robert; van Soest, Gijs

2015-01-01

Cardiac motion artifacts, non-uniform rotational distortion and undersampling affect the image quality and the diagnostic impact of intravascular optical coherence tomography (IV-OCT). In this study we demonstrate how these limitations of IV-OCT can be addressed by using an imaging system that we called “Heartbeat OCT”, combining a fast Fourier Domain Mode Locked laser, fast pullback, and a micromotor actuated catheter, designed to examine a coronary vessel in less than one cardiac cycle. We acquired in vivo data sets of two coronary arteries in a porcine heart with both Heartbeat OCT, working at 2.88 MHz A-line rate, 4000 frames/s and 100 mm/s pullback speed, and with a commercial system. The in vivo results show that Heartbeat OCT provides faithfully rendered, motion-artifact free, fully sampled vessel wall architecture, unlike the conventional IV-OCT data. We present the Heartbeat OCT system in full technical detail and discuss the steps needed for clinical translation of the technology. PMID:26713214

Geological nature of mineral licks and the reasons for geophagy among animals

Directory of Open Access Journals (Sweden)

A. M. Panichev

2017-06-01

Full Text Available In this paper, the reasons for geophagy (the eating of rocks by wild herbivores in two regions of the eastern Sikhote-Alin volcanic belt are considered. The mineralogical and chemical features of the consumed rocks, as well as the geological conditions of their formation, are investigated. A comparative analysis of the mineral and chemical composition of the consumed rocks and the excrement of the animals, almost completely consisting of mineral substances, is carried out. It is established that the consumed rocks are hydrothermally altered rhyolitic tuffs located in the volcanic calderas and early Cenozoic volcano-tectonic depressions. They consist of 30–65 % from zeolites (mainly clinoptilolites and smectites, possessing powerful sorption properties. According to the obtained data, the main reason for geophagy may be connected with the animals' urge to discard excessive and toxic concentrations of certain elements that are widespread in specific habitats and ingested with forage plants.

The chert workshop of Tozal de la Mesa (Alins del Monte, Huesca, Spain and its exploitation in historical times

Directory of Open Access Journals (Sweden)

Marta Sánchez de la Torre

2016-09-01

The first approach to contextualize the recovered materials of Tozal de la Mesa workshop area has allowed determining an exploitation of the Garumnian cherts that has lasted until the late nineteenth century according to some recovered products (e.g., pottery and to oral sources.

GenPlay Multi-Genome, a tool to compare and analyze multiple human genomes in a graphical interface.

Science.gov (United States)

Lajugie, Julien; Fourel, Nicolas; Bouhassira, Eric E

2015-01-01

Parallel visualization of multiple individual human genomes is a complex endeavor that is rapidly gaining importance with the increasing number of personal, phased and cancer genomes that are being generated. It requires the display of variants such as SNPs, indels and structural variants that are unique to specific genomes and the introduction of multiple overlapping gaps in the reference sequence. Here, we describe GenPlay Multi-Genome, an application specifically written to visualize and analyze multiple human genomes in parallel. GenPlay Multi-Genome is ideally suited for the comparison of allele-specific expression and functional genomic data obtained from multiple phased genomes in a graphical interface with access to multiple-track operation. It also allows the analysis of data that have been aligned to custom genomes rather than to a standard reference and can be used as a variant calling format file browser and as a tool to compare different genome assembly, such as hg19 and hg38. GenPlay is available under the GNU public license (GPL-3) from http://genplay.einstein.yu.edu. The source code is available at https://github.com/JulienLajugie/GenPlay. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Urgent need of a doctor

CERN Document Server

2003-01-01

GENEVE PATIENT NOT FIT TO BE MOVED: Call your family doctor Or : SOS MEDECINS (24H/24H) 022 748-49-50 Or : ASSOC. MEDECINS DE GENEVE (07H-23H) 022 322-20-20 PATIENT CAN BE MOVED: HOPITAL CANTONAL 24 Micheli du Crest 022 372-33-11 / 022 382-33-11 EMERGENCIES PEDIATRIQUES 30 Bd de la Cluse 022 382-45-55 MATERNITY 24 Micheli du Crest 022 382-68-16 / 022 382-33-11 CLINIQUE OPHTALMOLOGIQUE 22 Alcide Jentzer 022 382-84-00 HOPITAL DE LA TOUR Meyrin 022 719-61-11 EMERGENCIES ADULTS Meyrin 022 719-66-80 EMERGENCIES: AMBULANCES (GENEVE ET VAUD) 144 FIRE BRIGADE CERN 022 767-44-44 FIRE BRIGADE 118 POLICE 117 CENTRE ANTI-POISON 24H/24H: 01-251-51-51 EUROPEAN EMERGENCY CALL : 112 FRANCE PATIENT NOT FIT TO BE MOVED: Call your family doctor (or 15) PATIENT CAN BE MOVED: HOPITAL DE ST. JULIEN rue Amédée VIII de Savoie 04-50-49-65-65 EMERGENCIES rue Amédée VIII de Savoie 04-50-49-65-83 MATERNITY rue Amédée VIII de Savoie 04-50-49-66-07 HOPITAL D'ANNEMASSE 1...

URGENT NEED OF A DOCTOR

CERN Multimedia

2003-01-01

GENEVE PATIENT NOT FIT TO BE MOVED: Call your family doctor Or: SOS MEDECINS (24H/24H) 022 748-49-50 Or: ASSOC. MEDECINS DE GENEVE (07H-23H) 022 322-20-20 PATIENT CAN BE MOVED: HOPITAL CANTONAL 24 Micheli du Crest 022 372-33-11 / 022 382-33-11 EMERGENCIES PEDIATRIQUES 30 Bd de la Cluse 022 382-45-55 MATERNITY 24 Micheli du Crest 022 382-68-16 / 022 382-33-11 CLINIQUE OPHTALMOLOGIQUE 22 Alcide Jentzer 022 382-84-00 HOPITAL DE LA TOUR Meyrin 022 719-61-11 EMERGENCIES ADULTES Meyrin 022 719-66-80 EMERGENCIES: AMBULANCES (GENEVE ET VAUD) 144 FIRE BRIGADE CERN 022 767-44-44 FIRE BRIGADE 118 POLICE 117 CENTRE ANTI-POISON: 24H/24H 01-251-51-51 EUROPEAN EMERGENCY CALL: 112 FRANCE PATIENT NOT FIT TO BE MOVED: Call your family doctor (or 15) PATIENT CAN BE MOVED: HOPITAL DE ST. JULIEN rue Amédée VIII de Savoie 04-50-49-65-65 EMERGENCIES rue Amédée VIII de Savoie 04-50-49-65-83 MATERNITY rue Amédée VIII de Savoie 04-50-49-66-07 HOPITAL D'ANNEMASSE 17 r...

Presentations given at the regional conference on photovoltaic self-consumption

International Nuclear Information System (INIS)

Robert, Jacques; Loyen, Richard; Humbert, Adrien; Vache, Vincent; Soors, Corinne; Vienot, Raphaelle; Aries, Pierre; Bardon, Philippe; Dieny, Gauthier; Le Vannier, Isabelle; Joffre, Andre; Chardon, Julien; Charier, Gilles; Langevine, Agnes

2017-12-01

After the first national conference on photovoltaic self-consumption in May 2016, Enerplan, the French union of solar energy professionals, organised a first regional conference to inform its partners about the recent legal evolutions in this domain, to anticipate the next call for bids of the Commission of Energy Regulation, to benefit from the experience feedbacks of the last regional call for proposals and of project owners, and to discover the new opportunities of the decentralization and deregulation of local solar energy supplies. This document brings together the presentations given at this conference: 1 - New legal framework with the self-consumption decree of July 27, 2016: new opportunities and deadlines (Richard Loyen); 2 - Self-consumption in collective residential buildings, present-day legal framework (Adrien Humbert); 3 - Renewable energies self-consumption call for bids: priority targets and financial support (Vincent Vache); 4 - Enedis actions to simplify self-consumption (Corinne Soors); 5 - Regional context and experience feedback of the call for proposals (Raphaelle Vienot); 6 - Testimonies from project owners (Pierre Aries, Philippe Bardon, Gauthier Dieny, Isabelle Le Vannier); 7 - Decentralisation and deregulation of the local power supply: the block-chains big-bang in self-consumption (Andre Joffre); 8 - A new community platform for renewable electricity producers and consumers (Julien Chardon)

Knoto-ID: a tool to study the entanglement of open protein chains using the concept of knotoids.

Science.gov (United States)

Dorier, Julien; Goundaroulis, Dimos; Benedetti, Fabrizio; Stasiak, Andrzej

2018-05-02

The backbone of most proteins forms an open curve. To study their entanglement, a common strategy consists in searching for the presence of knots in their backbones using topological invariants. However, this approach requires to close the curve into a loop, which alters the geometry of curve. Knoto-ID allows evaluating the entanglement of open curves without the need to close them, using the recent concept of knotoids which is a generalization of the classical knot theory to open curves. Knoto-ID can analyse the global topology of the full chain as well as the local topology by exhaustively studying all subchains or only determining the knotted core. Knoto-ID permits to localize topologically non-trivial protein folds that are not detected by informatics tools detecting knotted protein folds. Knoto-ID is written in C ++ and includes R (www.R-project.org) scripts to generate plots of projections maps, fingerprint matrices and disk matrices. Knoto-ID is distributed under the GNU General Public License (GPL), version 2 or any later version and is available at https://github.com/sib-swiss/Knoto-ID. A binary distribution for Mac OS X, Linux and Windows with detailed user guide and examples can be obtained from https://www.vital-it.ch/software/Knoto-ID. julien.dorier@sib.swiss.

Small wind power plants : results of the Nordic wind diesel projects for large telecommunications companies; Implantation d'une centrale eolienne comme source d'energie d'appoint pour des stations de telecommunications

Energy Technology Data Exchange (ETDEWEB)

Ilinca, A.; Chaumel, J.L. [ATI Eolien, Rimouski, PQ (Canada); Thibault, G. [Entreprises MB, PQ (Canada)

2005-07-01

Two wind-diesel generating stations have been installed at telecommunication towers in the remote communities of Kuujjuarapik and Lac Julien in northern Quebec. The use of wind power contributes to the sustainable development in these remote areas by lowering the reliance on costly helicopter-transported diesel fuel and by reducing the release of greenhouse gases to the atmosphere. The technical characteristics of the Bergey 100 kW turbine with battery charger were presented along with the technical characteristics of the EolDie control panel that controls the supply of electricity from either the wind or diesel power generators. For the first time, the ATI-Wind technology system that was installed can supply the needs of the large telecommunication towers of Bell Canada and Telebec from either the wind or the diesel generators. The system is also capable of shutting down the diesel generators when wind energy is sufficient to take over. Early results from June 2005 showed that the diesel generators could be turned off for 55 per cent of the time. Preliminary results of these 2 projects were discussed by the firms in charge of the diesel and wind aspects and recommendations for improvements to the control systems were presented. 11 figs.

Electrical properties of dislocations in III-Nitrides

Energy Technology Data Exchange (ETDEWEB)

Cavalcoli, D.; Minj, A.; Pandey, S.; Cavallini, A. [Physics and Astronomy Dept. University of Bologna, Italy viale C Berti Pichat 6/II, Bologna (Italy)

2014-02-21

Research on GaN, AlN, InN (III-N) and their alloys is achieving new heights due their high potential applications in photonics and electronics. III-N semiconductors are mostly grown epitaxially on sapphire, and due to the large lattice mismatch and the differences in the thermal expansion coefficients, the structures usually contain many threading dislocations (TDs). While their structural properties have been widely investigated, their electrical characteristics and their role in the transport properties of the devices are still debated. In the present contribution we will show conductive AFM studies of TDs in GaN and Al/In GaN ternary alloys to evidence the role of strain, different surface polarity and composition on their electrical properties. Local I-V curves measured at TDs allowed us to clarify their role in the macroscopic electrical properties (leakage current, mobilities) of III-N based devices. Samples obtained by different growers (AIXTRON, III-V Lab) were studied. The comparison between the results obtained in the different alloys allowed us to understand the role of In and Al on the TDs electrical properties.

Electrical properties of dislocations in III-Nitrides

Science.gov (United States)

Cavalcoli, D.; Minj, A.; Pandey, S.; Cavallini, A.

2014-02-01

Research on GaN, AlN, InN (III-N) and their alloys is achieving new heights due their high potential applications in photonics and electronics. III-N semiconductors are mostly grown epitaxially on sapphire, and due to the large lattice mismatch and the differences in the thermal expansion coefficients, the structures usually contain many threading dislocations (TDs). While their structural properties have been widely investigated, their electrical characteristics and their role in the transport properties of the devices are still debated. In the present contribution we will show conductive AFM studies of TDs in GaN and Al/In GaN ternary alloys to evidence the role of strain, different surface polarity and composition on their electrical properties. Local I-V curves measured at TDs allowed us to clarify their role in the macroscopic electrical properties (leakage current, mobilities) of III-N based devices. Samples obtained by different growers (AIXTRON, III-V Lab) were studied. The comparison between the results obtained in the different alloys allowed us to understand the role of In and Al on the TDs electrical properties.

Complex regression Doppler optical coherence tomography

Science.gov (United States)

Elahi, Sahar; Gu, Shi; Thrane, Lars; Rollins, Andrew M.; Jenkins, Michael W.

2018-04-01

We introduce a new method to measure Doppler shifts more accurately and extend the dynamic range of Doppler optical coherence tomography (OCT). The two-point estimate of the conventional Doppler method is replaced with a regression that is applied to high-density B-scans in polar coordinates. We built a high-speed OCT system using a 1.68-MHz Fourier domain mode locked laser to acquire high-density B-scans (16,000 A-lines) at high enough frame rates (˜100 fps) to accurately capture the dynamics of the beating embryonic heart. Flow phantom experiments confirm that the complex regression lowers the minimum detectable velocity from 12.25 mm / s to 374 μm / s, whereas the maximum velocity of 400 mm / s is measured without phase wrapping. Complex regression Doppler OCT also demonstrates higher accuracy and precision compared with the conventional method, particularly when signal-to-noise ratio is low. The extended dynamic range allows monitoring of blood flow over several stages of development in embryos without adjusting the imaging parameters. In addition, applying complex averaging recovers hidden features in structural images.

Automated in vivo identification of fungal infection on human scalp using optical coherence tomography and machine learning

Science.gov (United States)

Dubey, Kavita; Srivastava, Vishal; Singh Mehta, Dalip

2018-04-01

Early identification of fungal infection on the human scalp is crucial for avoiding hair loss. The diagnosis of fungal infection on the human scalp is based on a visual assessment by trained experts or doctors. Optical coherence tomography (OCT) has the ability to capture fungal infection information from the human scalp with a high resolution. In this study, we present a fully automated, non-contact, non-invasive optical method for rapid detection of fungal infections based on the extracted features from A-line and B-scan images of OCT. A multilevel ensemble machine model is designed to perform automated classification, which shows the superiority of our classifier to the best classifier based on the features extracted from OCT images. In this study, 60 samples (30 fungal, 30 normal) were imaged by OCT and eight features were extracted. The classification algorithm had an average sensitivity, specificity and accuracy of 92.30, 90.90 and 91.66%, respectively, for identifying fungal and normal human scalps. This remarkable classifying ability makes the proposed model readily applicable to classifying the human scalp.

Raman Monte Carlo simulation for light propagation for tissue with embedded objects

Science.gov (United States)

Periyasamy, Vijitha; Jaafar, Humaira Bte; Pramanik, Manojit

2018-02-01

Monte Carlo (MC) stimulation is one of the prominent simulation technique and is rapidly becoming the model of choice to study light-tissue interaction. Monte Carlo simulation for light transport in multi-layered tissue (MCML) is adapted and modelled with different geometry by integrating embedded objects of various shapes (i.e., sphere, cylinder, cuboid and ellipsoid) into the multi-layered structure. These geometries would be useful in providing a realistic tissue structure such as modelling for lymph nodes, tumors, blood vessels, head and other simulation medium. MC simulations were performed on various geometric medium. Simulation of MCML with embedded object (MCML-EO) was improvised for propagation of the photon in the defined medium with Raman scattering. The location of Raman photon generation is recorded. Simulations were experimented on a modelled breast tissue with tumor (spherical and ellipsoidal) and blood vessels (cylindrical). Results were presented in both A-line and B-line scans for embedded objects to determine spatial location where Raman photons were generated. Studies were done for different Raman probabilities.

High-speed optical coherence tomography signal processing on GPU

International Nuclear Information System (INIS)

Li Xiqi; Shi Guohua; Zhang Yudong

2011-01-01

The signal processing speed of spectral domain optical coherence tomography (SD-OCT) has become a bottleneck in many medical applications. Recently, a time-domain interpolation method was proposed. This method not only gets a better signal-to noise ratio (SNR) but also gets a faster signal processing time for the SD-OCT than the widely used zero-padding interpolation method. Furthermore, the re-sampled data is obtained by convoluting the acquired data and the coefficients in time domain. Thus, a lot of interpolations can be performed concurrently. So, this interpolation method is suitable for parallel computing. An ultra-high optical coherence tomography signal processing can be realized by using graphics processing unit (GPU) with computer unified device architecture (CUDA). This paper will introduce the signal processing steps of SD-OCT on GPU. An experiment is performed to acquire a frame SD-OCT data (400A-linesx2048 pixel per A-line) and real-time processed the data on GPU. The results show that it can be finished in 6.208 milliseconds, which is 37 times faster than that on Central Processing Unit (CPU).

Conditions of formation for carbonaceous silicites of the continental margins

Energy Technology Data Exchange (ETDEWEB)

Bazhenova, O.K.

1986-06-01

Carbonaceous silicites occur in virtually all systems in Phanerozoic folded regions. They are of practical interest as concentrators of silver, molybdenum, vanadium, and nickel and as source and occasionally reservoir beds for petroleum. Some small oil pools occur in them in basins in Japan (Niigata and Akita), California, and East Sakhalin. Recently, interest has increased because a major pool was discovered in silicites of the Monterey formation: Point Arguello Hueso in the offshore part of the Santa Maria basin. Here the authors consider carbonaceous silicates in the western part of the Pacific active margin, which include Silurian and Devonian phthanites in the Mongolia-Okhotsk belt, and Triassic and Jurassic phthanites in the Sikhote-Alin area, although these rocks are of fairly local occurrence in the section. The authors have examined silicites in Kamchatka, Sakhalin, and Chukotka: diatomites, tuff-diatomites, and opokas, together with their recrystallized analogs. They occur in the Paleogene, but they are most abundant in the Miocene and Pliocene, as well as in the Jurassic, Cretaceous, and Eocene, particularly in the Miocene of California and Japan. 16 references.

Social structure and space use of Amur tigers (Panthera tigris altaica) in Southern Russian Far East based on GPS telemetry data.

Science.gov (United States)

Hernandez-Blanco, Jose A; Naidenko, Sergei V; Chistopolova, Maria D; Lukarevskiy, Victor S; Kostyrya, Alexey; Rybin, Alexandr; Sorokin, Pavel A; Litvinov, Mikhail N; Kotlyar, Andrey K; Miquelle, Dale G; Rozhnov, Viatcheslav V

2015-07-01

To better understand the spatial structure of Amur tigers (Panthera tigris altaica) at the southern edge of their range we fitted 14 tigers (6♀♀ and 8♂♂) with 15 GPS-Argos collars between 2008 and 2011 in 2 study sites: the Ussuriskii Reserve of southern Sikhote-Alin and the Land of the Leopard National Park in southwest Primorye, Russian Far East. Fixed kernel estimates of male home ranges were larger than those of female home ranges (P tiger populations and other areas of the Russian Far East, the sex ratio in our 2 study areas was highly skewed towards males. We believe this skewed sex ratio resulted in the dissolution of territoriality of males due to an inability to defend individual females, with males resorting to scramble competition for mates. Continued monitoring of these sites to determine whether shifts in the sex ratio might result in a return to male territoriality would provide confirmation of our tentative hypothesis. © 2015 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and Wiley Publishing Asia Pty Ltd.

FIELD CLASS AS PEDAGOGICAL PRACTICE IN TEACHING OF GEOGRAPHY FOR FUNDAMENTAL EDUCATION: proposed methodology and case study

Directory of Open Access Journals (Sweden)

Ricardo Michael Pinheiro Silveira

2014-01-01

Full Text Available In the context of significant change and transformation of society in recent decades at the global level, geography had to rethink its role in the condition of traditional discipline of the school curriculum. With the need for new teaching practices that apply to the daily lives of students, field classes emerge as an important activity to support the teaching of geography. At this perspective, based on recent results of the Project Expedições Geográficas (UFPR/Licenciar, this paper proposes a methodology for planning and organizing field classes at the local scale, based on three points: the pre-field (planning and organization stage, the field (realization of the activity and post-field (evaluation and discussion stage, which resulted in the case study with students from 6th grade (elementary school of Aline Picheth School, located in Curitiba/PR. Altogether six field classes were performed, with themes proposed initially, with emphasis on orientation/location, geotechnologies insertion and interpretation and recognition of landscape elements. The recorded proposals by the students during the activity denoted the fast assimilation of the contents against the reality experienced in loco, presenting satisfactory results and demonstrating the potential of the field class as an auxiliary teaching-pedagogical resource. RESUMO: No contexto das significativas mudanças e transformações da sociedade nas últimas décadas em nível global, a geografia teve de repensar sua função na condição de tradicional disciplina do currículo escolar. Com a necessidade de novas práticas pedagógicas que se apliquem ao cotidiano dos alunos, as aulas de campo surgem como importante atividade de apoio ao ensino de geografia. Nessa perspectiva, com base nos resultados recentes do Projeto Expedições Geográficas (UFPR/Licenciar, o presente trabalho propõe uma metodologia para o planejamento e organização de aulas de campo em escala local, pautada em tr

Causes and Model Skill of the Persistent Intense Rainfall and Flooding in Paraguay during the Austral Summer 2015-2016

Science.gov (United States)

Doss-Gollin, J.; Munoz, A. G.; Pastén, M.

2017-12-01

During the austral summer 2015-16 severe flooding displaced over 150,000 people on the Paraguay River system in Paraguay, Argentina, and Southern Brazil. This flooding was out of phase with the typical seasonal cycle of the Paraguay River, and was driven by repeated intense rainfall events in the Lower Paraguay River basin. Using a weather typing approach within a diagnostic framework, we show that enhanced moisture inflow from the low-level jet and local convergence associated with baroclinic systems favored the development of mesoscale convective activity and enhanced precipitation. The observed circulation patterns were made more likely by the cross-timescale interactions of multiple climate mechanisms including the strong, mature El Niño event and an active Madden-Julien Oscillation in phases four and five. We also perform a comparison of the rainfall predictability using seasonal forecasts from the Latin American Observatory of Climate Events (OLE2) and sub-seasonal forecasts produced by the ECMWF. We find that the model output precipitation field exhibited limited skill at lead times beyond the synoptic timescale, but that a Model Output Statistics (MOS) approach, in which the leading principal components of the observed rainfall field are regressed on the leading principal components of model-simulated rainfall fields, substantially improves spatial representation of rainfall forecasts. Possible implications for flood preparedness are briefly discussed.

Conference on new consumption and commercialization models for photovoltaic energy

International Nuclear Information System (INIS)

Freier, Karin; Fontaine, Pierre; Mayer, Joerg; Jimenez, Julien; Richard, Pascal; Vogtmann, Michael; Schaefer, Felix; Martin, Nicolas; Buis, Sabine

2014-01-01

The French-German office for Renewable energies (OFAEnR) organised a conference on new consumption and commercialization models for photovoltaic energy. In the framework of this French-German exchange of experience, about 120 participants exchanged views on the new economic models for solar energy producers while the photovoltaic industry has to face a progressive reduction of feed-in tariffs and of other incentive mechanisms. Beside the legal and economic aspects, technical questions around energy storage and integration of photovoltaic production to the grid were also addressed. This document brings together the available presentations (slides) made during this event: 1 - Stimulating self-consumption and direct selling within the EEG (Karin Freier); 2 - Development of PV self-consumption in France (Pierre Fontaine); 3 - experience from applying the new support program for solar energy storage systems (Joerg Mayer); 4 - Call for solar photovoltaic projects for own consumption in Aquitaine region (Julien Jimenez); 5 - SMA Flexible Storage System - New version of the Sunny Island inverter for smart photovoltaic energy storage (Pascal Richard); 6 - PV Own Consumption in industry and commerce - examples und Operating Concepts (Michael Vogtmann); 7 - Supplying tenants in multiple-family housing with solar power in the 'Neue Heimat' project (Felix Schaefer); 8 - How to manage PV-storage self-consumption from a grid point of view? (Nicolas Martin); 9 - Closing talk (Sabine Buis)

Dynamic changes of carbon isotope apparent fractionation factor to describe transition to syntrophic acetate oxidation during cellulose and acetate methanization.

Science.gov (United States)

Vavilin, Vasily A; Rytov, Sergey V

2017-05-01

To identify predominant metabolic pathway for cellulose methanization new equations that take into account dynamics of 13C are added to the basic model of cellulose methanization. The correct stoichiometry of hydrolysis, acidogenesis, acetogenesis and methanogenesis steps including biomass is considered. Using experimental data by Laukenmann et al. [Identification of methanogenic pathway in anaerobic digesters using stable carbon isotopes. Eng. Life Sci. 2010;10:1-6], who reported about the importance of ace`tate oxidation during mesophilic cellulose methanization, the model confirmed that, at high biomass concentration of acetate oxidizers, the carbon isotope fractionation factor amounts to about 1.085. The same model, suggested firstly for cellulose degradation, was used to describe, secondly, changes in, and in methane and carbon dioxide during mesophylic acetate methanization measured by Grossin-Debattista [Fractionnements isotopiques (13C/12C) engendres par la methanogenese: apports pour la comprehension des processus de biodegradation lors de la digestion anaerobie [doctoral thesis]. 2011. Bordeaux: Universite Bordeaux-1;2011. Available from: http://ori-oai.u-bordeaux1.fr/pdf/2011/GROSSIN-DEBATTISTA_JULIEN_2011.pdf . French].The model showed that under various ammonium concentrations, at dominating acetoclastic methanogenesis, the value decreases over time to a low level (1.016), while at dominating syntrophic acetate oxidation, coupled with hydrogenotrophic methanogenesis, slightly increases, reaching 1.060 at the end of incubation.

URGENT NEED OF A DOCTOR

CERN Document Server

2003-01-01

GENEVE PATIENT NOT FIT TO BE MOVED: Call your family doctor Or : SOS MEDECINS (24H/24H) 022 748-49-50 Or : ASSOC. MEDECINS DE GENEVE (07H-23H) 022 322-20-20 PATIENT CAN BE MOVED: HOPITAL CANTONAL 24 Micheli du Crest 022 372-33-11 / 022 382-33-11 EMERGENCIES PEDIATRIQUES 30 Bd de la Cluse 022 382-45-55 MATERNITY 24 Micheli du Crest 022 382-68-16 / 022 382-33-11 CLINIQUE OPHTALMOLOGIQUE 22 Alcide Jentzer 022 382-84-00 HOPITAL DE LA TOUR Meyrin 022 719-61-11 EMERGENCIES ADULTES Meyrin 022 719-66-80 EMERGENCIES: AMBULANCES (GENEVE ET VAUD) 144 FIRE BRIGADE CERN 022 767-44-44 FIRE BRIGADE 118 POLICE 117 CENTRE ANTI-POISON: 24H/24H 01-251-51-51 EUROPEAN EMERGENCY CALL: 112 FRANCE PATIENT NOT FIT TO BE MOVED: Call your family doctor (or 15) PATIENT CAN BE MOVED: HOPITAL DE ST. JULIEN rue Amédée VIII de Savoie 04-50-49-65-65 EMERGENCIES rue Amédée VIII de Savoie 04-50-49-65-83 MATERNITY rue Amédée VIII de Savoie 04-50-49-66-07 HOPITAL D'ANNEMASSE 17 rue du Jura, Ambilly 04-50-87-47-47 EMERGENCIES 17 rue...

Comparison of auditory evoked potentials and the A-line ARX Index for monitoring the hypnotic level during sevoflurane and propofol induction

DEFF Research Database (Denmark)

Litvan, H; Jensen, E W; Revuelta, M

2002-01-01

Extraction of the middle latency auditory evoked potentials (AEP) by an auto regressive model with exogenous input (ARX) enables extraction of the AEP within 1.7 s. In this way, the depth of hypnosis can be monitored at almost real-time. However, the identification and the interpretation of the a......Extraction of the middle latency auditory evoked potentials (AEP) by an auto regressive model with exogenous input (ARX) enables extraction of the AEP within 1.7 s. In this way, the depth of hypnosis can be monitored at almost real-time. However, the identification and the interpretation...

Las astillas del racionalismo: la crisis del pensamiento moderno en la narrativa mexicana contemporánea

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Lilia Leticia García Peña

2011-01-01

Full Text Available Una de las grandes herencias de la modernidad es el ejercicio del racion alismo, su cuestion amiento y fragmentación es la cons tante de las formas subvertidas del pensamiento a partir de la segunda mitad del siglo veinte. La narrativa mexicana contemporánea muestra esta realidad a través de la representación de personajes que piensan obsesivamente, así como del cuestion amiento intenso de los límites neuronales y racionales del ser humano. El trabajo analiza el imaginario simbólico de este proceso de la narrativa mexicana en cuatro casos fundantes del siglo veinte, Juan Rulfo, José Revueltas, Rosario Castellanos y Luis Carrión, y en cuatro obras de los albores del siglo veintiuno de Aline Pettersson, Pedro Áng el Palou, Patricia Laurent Kullick y Socorro Venegas. Desde el punto de vista de losos referentes teórico-o-críticos literarios, el trabajo parte de los planteamientos mitocríticos de Gilbert Durand, discursivos de Mijaíl Bajtín y semióticos de Iuri Lotman.

Diseño de un modelo de migración a cloud computing para entidades públicas de salud

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C Guti

2017-10-01

Full Text Available Objetivo: diseñar un modelo Cloud Computing que permitirá a las empresas manejar la información, reducir  costos, maximizar servicios y utilizar tecnología de punta. Metodología: construir un modelo que genere rompimiento en el paradigma mental de los directores de las áreas de TI mediante una investigación descriptiva, realizando una observación al personal que trabaja en TI. Resultados: se diseñó un modelo de migración basado en estrategias de diferentes autores y en la experiencia de un grupo de especialistas de un Data Center que podría servir como guía para futuras implementaciones en los hospitales de II nivel del departamento del Valle del Cauca. Conclusiones: el modelo permitirá a los hospitales realizar la migración de su área de TI a un Data Center, alineándose  con las políticas gubernamentales y  ubicarse a la vanguardia en tecnología y estar a la par de multinacionales que poseen grandes recursos económicos.

Spectroscopic Doppler analysis for visible-light optical coherence tomography

Science.gov (United States)

Shu, Xiao; Liu, Wenzhong; Duan, Lian; Zhang, Hao F.

2017-12-01

Retinal oxygen metabolic rate can be effectively measured by visible-light optical coherence tomography (vis-OCT), which simultaneously quantifies oxygen saturation and blood flow rate in retinal vessels through spectroscopic analysis and Doppler measurement, respectively. Doppler OCT relates phase variation between sequential A-lines to the axial flow velocity of the scattering medium. The detectable phase shift is between -π and π due to its periodicity, which limits the maximum measurable unambiguous velocity without phase unwrapping. Using shorter wavelengths, vis-OCT is more vulnerable to phase ambiguity since flow induced phase variation is linearly related to the center wavenumber of the probing light. We eliminated the need for phase unwrapping using spectroscopic Doppler analysis. We split the whole vis-OCT spectrum into a series of narrow subbands and reconstructed vis-OCT images to extract corresponding Doppler phase shifts in all the subbands. Then, we quantified flow velocity by analyzing subband-dependent phase shift using linear regression. In the phantom experiment, we showed that spectroscopic Doppler analysis extended the measurable absolute phase shift range without conducting phase unwrapping. We also tested this method to quantify retinal blood flow in rodents in vivo.

Aline Ferreira & John W. Schwieter (eds.) (2015) Psycholinguistic and Cognitive Inquiries into Translation and Interpreting [Benjamins Translation Library 115] Amsterdam : John Benjamins

DEFF Research Database (Denmark)

Lykke Jakobsen, Arnt

2017-01-01

the most fruitful interaction of all has been with cognitive sciences, including neuroscience, cognitive psychology, and psycholinguistics. Volume 115 in the Benjamins Translation Library series aims at illustrating this latter trend by presenting the current state of the art in cognitively oriented...

Exploring the State of Unbalance within the Topical and Heterotopical Spaces at the Core of Story

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Mahshad Jalalpourroodsari

2013-01-01

Full Text Available This paper examines one of the ways in which narrativity as a complex concept is rooted in almost simple notions which support it at its basic levels. The discussion here would be devoted to the concept of the minimal story (récit minimal which is defined as being part of the surface narrative syntax of every discourse in general and Ibsen’s A Doll’s House in particular. It will be seen how the play’s content signs are converted via the minimal story and how the supporting pillars of this discourse are grounded in elementary types of narrative programmes which cement the trajectory (Note 1 of meaning at its surface stratum. The basis of this research is the semiotic theory proposed by the French structuralist semiotician Algirdas Julien Greimas as the founder of Paris School of semiotics. It will be seen how the story can arrange itself from its end and how the whole narrative process may possess a temporal and syntactic orientation which forms the bare structure around which the whole story is weaved. This paper attempts to shed some light on the inner fluctuations at the heart of Ibsen’s play accommodating an orientational schema which the semioticians would call the nucleus of all narrative systems. Therefore, in this article, an introduction of the basic concepts will be followed by an analysis of the turbulences affecting the main figures/actants (Note 2 inhabiting the minimal story of Ibsen’s discourse.

Delineating Two Exclusive Views on Power of Choosing and Modal Dynamics of Double Performances

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Mahshad Jalalpourroodsari

2012-11-01

Full Text Available This article endeavors to make use of the theories presented by French semiotician Algirdas Julien Greimas, in order to demonstrate the main structural exchanges inherent within some of the critical choices and acute performances at the heart of Ibsen’s A Doll’s House. In this study, the syntagmatic exchange structures and the paradigmatic structures of gift and test which are at work within the narrative line of the play are discussed and exteriorized so that there can be a better apprehension and appreciation for the internal path of signification concerning the relation of the main couple actants (Note 1 in this discourse. It will be seen how the power to choose of the protagonists of exchange or loci of exchange structures might be exercised or overlooked and how one may devalorise and negate an offer of exchange based on the way it is modally interpreted. This study will contemplate on the manner in which one’s voluntary renunciation of rights may metamorphose into a manipulative and deceptive dispossession of that right, when actants get involved in parallel programmes which are complementary and at the same time contradictory to one another. Thus, through adopting such a perspective towards the choices made and the dilemmas faced by the main actants of Ibsen’s discourse, one gets the chance to have a more tangible canvas on which to draw Nora and Torvald’s change of hearts and malfunctioning transactions.

Oncolytic viruses: a step into cancer immunotherapy

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Pol JG

2011-12-01

Full Text Available Jonathan G Pol, Julien Rességuier, Brian D LichtyMcMaster Immunology Research Centre, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, CanadaAbstract: Oncolytic virotherapy is currently under investigation in phase I–III clinical trials for approval as a new cancer treatment. Oncolytic viruses (OVs selectively infect, replicate in, and kill tumor cells. For a long time, the therapeutic efficacy was thought to depend on the direct viral oncolysis (virocentric view. The host immune system was considered as a brake that impaired virus delivery and spread. Attention was paid primarily to approaches enhancing virus tumor selectivity and cytotoxicity and/or that limited antiviral responses. Thinking has changed over the past few years with the discovery that OV therapy was also inducing indirect oncolysis mechanisms. Among them, induction of an antitumor immunity following OV injection appeared to be a key factor for an efficient therapeutic activity (immunocentric view. Indeed, tumor-specific immune cells persist post-therapy and can search and destroy any tumor cells that escape the OVs, and thus immune memory may prevent relapse of the disease. Various strategies, which are summarized in this manuscript, have been developed to enhance the efficacy of OV therapy with a focus on its immunotherapeutic aspects. These include genetic engineering and combination with existing cancer treatments. Several are currently being evaluated in human patients and already display promising efficacy.Keywords: oncolytic virus, cancer immunotherapy, tumor antigen, cancer vaccine, combination strategies

Material rhetoric: spreading stones and showing bones in the study of prehistory.

Science.gov (United States)

Van Reybrouck, David; de Bont, Raf; Rock, Jan

2009-06-01

Since the linguistic turn, the role of rhetoric in the circulation and the popular representation of knowledge has been widely accepted in science studies. This article aims to analyze not a textual form of scientific rhetoric, but the crucial role of materiality in scientific debates. It introduces the concept of material rhetoric to understand the promotional regimes in which material objects play an essential argumentative role. It analyzes the phenomenon by looking at two students of prehistory from nineteenth-century Belgium. In the study of human prehistory and evolution, material data are either fairly abundant stone tools or very scarce fossil bones. These two types of material data stand for two different strategies in material rhetoric. In this article, the first strategy is exemplified by Aimé Rutot, who gathered great masses of eoliths (crudely chipped stones which he believed to be prehistoric tools). The second strategy is typified by the example of Julien Fraipont, who based his scientific career on only two Neanderthal skeletons. Rutot sent his "artifacts" to a very wide audience, while Fraipont showed his skeletons to only a few selected scholars. Unlike Rutot, however, Fraipont was able to monitor his audience's interpretation of the finds by means of personal contacts. What an archaeologist gains in reach, he or she apparently loses in control. In this article we argue that only those scholars who find the right balance between the extremes of reach and control will prove to be successful.

Geochemistry Petrography, thermobarometry and investigation of magmatic series in Mirabad- Chehel Khane granitoid body (east of Bouin– Miandasht, Isfahan province

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Seyed Mohsen Tabatabaei Manesh

2017-11-01

Full Text Available On the base of petrology, the Mirabad- Chehel Khane granitoid, east of Bouin-Miandasht, dominantly consists of syenogranite, monzogranite, alkali granite and granodiorites. The main minerals of these rocks are quartz, alkali feldspar (Orthoclase, plagioclase (Albite - Oligoclase, biotite, ± amphibole with minor amount of allanite, zircon, titanite, apatite, ± tourmaline.  The biotite from the granites are Fe-rich type (annite and primary magmatic in origin. The composition of the biotites studied principally falls in the calc-alkaline subduction related I-type granite on the tectonomagmatic discrimination diagrams, which stand on their major element oxides. Which is consistent with the nature of their host rocks. The studied amphiboles are classified as calcic (ferro-hornblende which points to the I-type nature of the granitoid.  The tourmaline composition plots on the schorl - foitite field. The temperature for the alteration, on the base of chlorite composition from the syenogranite, is estimated around 350°C and from the monzogranite rocks about 341°C.  Based on the application of Al-in amphibole, a 3 Kbar pressure was determined for the syenogranite unit corresponding to the depth of 8-11 Km for the emplacement of the pluton. Hornblende- plagioclase thermometer shows 694 to 700°C for the equilibrium of these two minerals.

Transthoracic ultrasound in the assessment of pleural and pulmonary diseases: use and limitations.

Science.gov (United States)

Sperandeo, Marco; Rotondo, Antonio; Guglielmi, Giuseppe; Catalano, Daniela; Feragalli, Beatrice; Trovato, Guglielmo M

2014-10-01

Interest in transthoracic ultrasound (US) procedures increased after the availability of portable US equipment suitable for use at the patient's bedside. It is possible to detect space-occupying lesions of the pleura, pleural effusion, focal or diffuse pleural thickening and subpleural lesions of the lung, even in emergency settings. Transthoracic US is useful as a guidance system for thoracentesis and peripheral lesion biopsy, where it minimises the occurrence of pneumothorax and haemorrhage. Transthoracic US imaging is strongly influenced by physical interaction of the ultrasonic beam at the tissue/air interface, which gives rise to reverberations classified as simple (A-line), "comet tail" and "ring down"(B-line) artifacts. Although these artifacts can be suggestive of a disease condition, they are essentially imaging errors present even in normal subjects and in empty-pleura post-pneumonectomy patients. In order to clarify some confusion and to report on the state of the art, we present a review of the literature on transthoracic US in diseases of the pleura and peripheral lung regions and our own clinical experience over 3 decades. The review focuses on quality assurance procedures and their value in diagnostic imaging and patient monitoring and warns against possible inappropriate indications and misleading information. Thoracic US is much more than "fishing for the moon in the well".

L’exercice fédéré des compétences locales. À propos de la fonction de «chef de file» en droit des collectivités territoriales français

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Cédric Groulier

2009-06-01

Full Text Available La révision constitutionnelle du 28 mars 2003 a introduit dans le droit des collectivités territoriales un dispositif que l’on pourrait qualifier d’exercice fédéré des compétences locales. Selon l’article 72 alinéa 5 de la Constitution, lorsque l’exercice d’une compétence nécessite le concours de plusieurs collectivités territoriales, la loi peut autoriser l’une d’entre elles ou un de leurs groupements à organiser les modalités de leur action commune, autrement dit à exercer les fonctions de chef de file. À travers cette figure du chef de file, la Constitution semble admettre un principe de superposition entre collectivités territoriales, dérogeant à la règle de l’interdiction des tutelles entre collectivités, liée à leur liberté d’administration. Toutefois, la portée effective de ce nouveau dispositif repose sur sa mise en œuvre législative : or, le législateur fait montre d’une grande réserve, sans doute injustifiée, qui maintient l’idée de superposition entre collectivités à l’état de virtualité.

Recovery Temperature, Transition, and Heat Transfer Measurements at Mach 5

Science.gov (United States)

Brinich, Paul F.

1961-01-01

Schlieren, recovery temperature, and heat-transfer measurements were made on a hollow cylinder and a cone with axes alined parallel to the stream. Both the cone and cylinder were equipped with various bluntnesses, and the tests covered a Reynolds number range up to 20 x 10(exp 6) at a free-stream Mach number of 4.95 and wall to free-stream temperature ratios from 1.8 to 5.2 (adiabatic). A substantial transition delay due to bluntness was found for both the cylinder and the cone. For the present tests (Mach 4.95), transition was delayed by a factor of 3 on the cylinder and about 2 on the cone, these delays being somewhat larger than those observed in earlier tests at Mach 3.1. Heat-transfer tests on the cylinder showed only slight effects of wall temperature level on transition location; this is to be contrasted to the large transition delays observed on conical-type bodies at low surface temperatures at Mach 3.1. The schlieren and the peak-recovery-temperature methods of detecting transition were compared with the heat-transfer results. The comparison showed that the first two methods identified a transition point which occurred just beyond the end of the laminar run as seen in the heat-transfer data.

Ground-water resources of the Sevier River basin between Yuba Dam and Leamington Canyon, Utah

Science.gov (United States)

Bjorklund, Louis Jay; Robinson, Gerald B.

1968-01-01

The area investigated is a segment of the Sevier River basin, Utah, comprising about 900 square miles and including a 19-mile reach of the Sevier River between Yuba Dam and Leamington Canyon. The larger valleys in the area are southern Juab, Round, and Scipio Valleys. The smaller valleys are Mills, Little, Dog, and Tinctic Wash Valleys.The geology of parts of Scipio, Little, and Mills Valleys and parts of the surrounding highlands was mapped and studied to explain the occurrence of numerous sinkholes in the thre valleys and to show their relation to the large springs in Mills Valley. The sinkholes, which are formed in the alluvium, are alined along faults, which penetrate both the alluvium and the underlying bedrock, and they have been formed by collapse of solution cavities in the underlying bedrock. The bedrock is mostly sandy limestone beds of the upper part of the North Horn Formation and of the Flagstaff Limestone. The numerous faults traversing Scipio Valley in a north-northeasterly direction trend directly toward Molter and Blue Springs in Mills Valley. One fault, which can be traced directly between the springs, probably is the principal channelway for the ground water moving from Scipio and Little Valleys to the springs.

A hybrid positron and OCT intraoperative probe for ovarian cancer detection and characterization

Science.gov (United States)

Yang, Yi; Biswal, Nrusingh C.; Wang, Tianheng; Kumavor, Patrick; Karimeddini, Mozafareddin; Sanders, Melinda; Brewer, Molly; Zhu, Quing

2011-03-01

Ovarian cancer has the lowest survival rate of the gynecologic cancers with a 5-year survival of about 50% in the United States. With current screening and diagnostic abilities for ovarian cancers, most of the diagnosed patients are already with advanced stages and the majority of them will die of this deadly disease. In this paper, we report a multimodal imaging approach which combines optical coherence tomography (OCT) and positron detection for early ovarian cancer detection. The dual modality system has the capability of providing both functional and morphological images simultaneously. While the positron detection provides the metabolism activity of the ovary due to the uptake of radiotracer, the OCT provides the high resolution (25μm X 25μm X 12μm - longitudinal X lateral X axial in air) structural imaging at 20k A-lines per second. Total 18 ovaries obtained from 10 patients classified as normal, abnormal and malignant ovarian tissues were characterized ex vivo. Positron counts of 1.2-fold higher was found between abnormal and normal ovaries and 3~30-fold higher was found between malignant and normal ovaries. OCT imaging of malignant and abnormal ovaries revealed many detailed morphologic features that could be potentially valuable for detecting early malignant changes in the ovary.

Models to teach lung sonopathology and ultrasound-guided thoracentesis

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Jacek A. Wojtczak

2014-12-01

Full Text Available Lung sonography allows rapid diagnosis of lung emergencies such as pulmonary edema, hemothorax or pneumothorax. The ability to timely diagnose an intraoperative pneumothorax is an important skill for the anesthesiologist. However, lung ultrasound exams require an interpretation of not only real images but also complex acoustic artifacts such as A-lines and B-lines. Therefore, appropriate training to gain proficiency is important. Simulated environment using ultrasound phantom models allows controlled, supervised learning. We have developed hybrid models that combine dry or wet polyurethane foams, porcine rib cages and human hand simulating a rib cage. These models simulate fairly accurately pulmonary sonopathology and allow supervised teaching of lung sonography with the immediate feedback. In-vitro models can also facilitate learning of procedural skills, improving transducer and needle positioning and movement, rapid recognition of thoracic anatomy and hand – eye coordination skills. We described a new model to teach an ultrasound guided thoracentesis. This model consists of the experimenter’s hand placed on top of the water-filled container with a wet foam. Metacarpal bones of the human hand simulate a rib cage and a wet foam simulates a diseased lung immersed in the pleural fluid. Positive fluid flow offers users feedback when a simulated pleural effusion is accurately assessed.

On the dynamics of compound bedforms in high-energy tidal channels: field observations in the German Bight and the Danish Wadden Sea

Science.gov (United States)

Ernstsen, Verner B.; Winter, Christian; Becker, Marius; Bartholdy, Jesper

2010-05-01

Tidal inlets are a common feature along much of the world's coastlines. They interrupt the alongshore continuity of shoreline processes, and by being exposed to both wave and current forcing, tidal inlets belong to the morphologically most dynamic and complex coastal systems on Earth. The tidal channels in these inlets are characterized by high flow velocities and, accordingly, the channel beds are typically sandy and covered with bedforms. The bedform fields in nature are often complex systems with larger primary-bedforms superimposed by smaller secondary-bedforms (cf. Bartholdy et al., 2002). There is a considerable amount of detailed field investigations on the dynamics of primary-bedforms at various temporal scales, ranging from short- to long-term tide-related cycles to flood hydrographs to seasonality. However, Julien et al. (2002) stated that a composite analysis of primary- and secondary-bedforms is recommended for future studies on resistance to flow. Such knowledge on the behaviour of compound bedforms is still deficient. In this study, we combine the findings on the dynamics of primary- and secondary-bedform height from detailed field investigations carried out in two high-energy tidal channels during 2007 and 2008: the Knudedyb tidal inlet channel in the Danish Wadden Sea and the Innenjade tidal channel in the Jade Bay, German Bight (both survey areas being ebb-dominated). We provide process-based explanations of the bedform behaviour and present a conceptual model of compound bedform dynamics. The conducted field investigations comprised repetitive, simultaneous measurements of high-resolution swath bathymetry (using a multibeam echosounder system) and flow velocity (using an acoustic Doppler current profiler) in combination with detailed spatial mapping of bed material characteristics (from grab sampling of bed material). For an objective and discrete analysis of primary- and secondary-bedforms a modified version of the bedform tracking tool

Three-dimensional interactive Molecular Dynamics program for the study of defect dynamics in crystals

Science.gov (United States)

Patriarca, M.; Kuronen, A.; Robles, M.; Kaski, K.

2007-01-01

The study of crystal defects and the complex processes underlying their formation and time evolution has motivated the development of the program ALINE for interactive molecular dynamics experiments. This program couples a molecular dynamics code to a Graphical User Interface and runs on a UNIX-X11 Window System platform with the MOTIF library, which is contained in many standard Linux releases. ALINE is written in C, thus giving the user the possibility to modify the source code, and, at the same time, provides an effective and user-friendly framework for numerical experiments, in which the main parameters can be interactively varied and the system visualized in various ways. We illustrate the main features of the program through some examples of detection and dynamical tracking of point-defects, linear defects, and planar defects, such as stacking faults in lattice-mismatched heterostructures. Program summaryTitle of program:ALINE Catalogue identifier:ADYJ_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADYJ_v1_0 Program obtainable from: CPC Program Library, Queen University of Belfast, N. Ireland Computer for which the program is designed and others on which it has been tested: Computers:DEC ALPHA 300, Intel i386 compatible computers, G4 Apple Computers Installations:Laboratory of Computational Engineering, Helsinki University of Technology, Helsinki, Finland Operating systems under which the program has been tested:True64 UNIX, Linux-i386, Mac OS X 10.3 and 10.4 Programming language used:Standard C and MOTIF libraries Memory required to execute with typical data:6 Mbytes but may be larger depending on the system size No. of lines in distributed program, including test data, etc.:16 901 No. of bytes in distributed program, including test data, etc.:449 559 Distribution format:tar.gz Nature of physical problem:Some phenomena involving defects take place inside three-dimensional crystals at times which can be hardly predicted. For this reason they are

Stochastic Parametrisations and Regime Behaviour of Atmospheric Models

Science.gov (United States)

Arnold, Hannah; Moroz, Irene; Palmer, Tim

2013-04-01

The presence of regimes is a characteristic of non-linear, chaotic systems (Lorenz, 2006). In the atmosphere, regimes emerge as familiar circulation patterns such as the El-Nino Southern Oscillation (ENSO), the North Atlantic Oscillation (NAO) and Scandinavian Blocking events. In recent years there has been much interest in the problem of identifying and studying atmospheric regimes (Solomon et al, 2007). In particular, how do these regimes respond to an external forcing such as anthropogenic greenhouse gas emissions? The importance of regimes in observed trends over the past 50-100 years indicates that in order to predict anthropogenic climate change, our climate models must be able to represent accurately natural circulation regimes, their statistics and variability. It is well established that representing model uncertainty as well as initial condition uncertainty is important for reliable weather forecasts (Palmer, 2001). In particular, stochastic parametrisation schemes have been shown to improve the skill of weather forecast models (e.g. Berner et al., 2009; Frenkel et al., 2012; Palmer et al., 2009). It is possible that including stochastic physics as a representation of model uncertainty could also be beneficial in climate modelling, enabling the simulator to explore larger regions of the climate attractor including other flow regimes. An alternative representation of model uncertainty is a perturbed parameter scheme, whereby physical parameters in subgrid parametrisation schemes are perturbed about their optimal value. Perturbing parameters gives a greater control over the ensemble than multi-model or multiparametrisation ensembles, and has been used as a representation of model uncertainty in climate prediction (Stainforth et al., 2005; Rougier et al., 2009). We investigate the effect of including representations of model uncertainty on the regime behaviour of a simulator. A simple chaotic model of the atmosphere, the Lorenz '96 system, is used to study

Seasonal and Daily Dynamics of the CO2 Emission from Soils of Pinus koraiensis Forests in the South of the Sikhote-Alin Range

Science.gov (United States)

Ivanov, A. V.; Braun, M.; Tataurov, V. A.

2018-03-01

The presented study shows the results of measuring soil respiration in typical burozems (Dystric Cambisols) under mixed Korean pine-broadleaved forests in the southern part of the Primorskii (Far East) region of Russia growing under conditions of monsoon climate. The measurements were performed in 2014-2016 by the chamber method with the use of a portable infrared gas analyzer. Relative and total values of the CO2 efflux from the soil surface on four model plots were determined. The intensity of summer emission varied from 2.25 to 10.97 μmol/(m2 s), and the total CO2 efflux from the soils of four plots varied from 18.84 to 25.56 mol/m2. It is shown that a larger part of seasonal variability in the soil respiration is controlled by the soil temperature ( R 2 = 0.5-0.7); the soil water content also has a significant influence on the CO2 emission determining about 10% of its temporal variability. The daily dynamics of soil respiration under the old-age (200 yrs) forest have a significant relationship with the soil temperature ( R 2 = 0.51). The pyrogenic transformation of Pinus koraiensis forests into low-value oak forests is accompanied by an increase in the CO2 efflux from the soil.

Status of the interoceanic canal study

Energy Technology Data Exchange (ETDEWEB)

Groves, R H [Engineering Agent for the Atlantic-Pacific, Interoceanic Canal Study Commission (United States)

1970-05-01

The studies of Atlantic-Pacific Interoceanic Sea-Level Canal Study Commission are are not as yet completed, although there is no reason at this time to doubt that the 1 December 1970 deadline for the Commission's final report will be met. Since it has not been published, I am unable to pass on to you any of its conclusions; they simply do not exist today. And it would be improper for me to reveal the substance of the Commission's deliberations to date or to speculate upon what their outcome may be. But many elements of the work being conducted under my supervision - The Engineering Feasibility Study - are already in the public domain. It is to them that my remarks here are addressed. Of the six basic routes we have considered in our studies for possible sea-level canal alinements, four could involve nuclear excavating techniques. The so-called nuclear alternatives are Route 8 along the Nicaragua-Costa Rica border, Route 17 across the Darien Isthmus of Panama, Route 23 crossing the Panama-Colombia border and Route 25 across the western tip of Colombia. The conventionally excavated routes are Route 10 west of the Panama Canal Zone and Route 14 along the alinement of the present canal. The engineering studies examine from a technical standpoint the feasibility of constructing these routes and estimate their costs. To accomplish this we have made conceptual designs for canals capable of transiting at least 40,000 vessels annually (and possibly several times that many) and of accommodating ships of up to 250,000 dwt in size. Thus, in terms of basic requirements, all alternatives - conventional and nuclear - have been made comparable. Beginning with the northernmost route, let us now consider the four nuclear alternatives. Route 8 is 137 miles in length. Its maximum elevations are slightly less than 800 feet in the Continental Divide and about 400 feet through the so-called Eastern Divide. The rock to be excavated is primarily volcanic tuff. It is readily apparent that

Status of the interoceanic canal study

International Nuclear Information System (INIS)

Groves, R.H.

1970-01-01

The studies of Atlantic-Pacific Interoceanic Sea-Level Canal Study Commission are are not as yet completed, although there is no reason at this time to doubt that the 1 December 1970 deadline for the Commission's final report will be met. Since it has not been published, I am unable to pass on to you any of its conclusions; they simply do not exist today. And it would be improper for me to reveal the substance of the Commission's deliberations to date or to speculate upon what their outcome may be. But many elements of the work being conducted under my supervision - The Engineering Feasibility Study - are already in the public domain. It is to them that my remarks here are addressed. Of the six basic routes we have considered in our studies for possible sea-level canal alinements, four could involve nuclear excavating techniques. The so-called nuclear alternatives are Route 8 along the Nicaragua-Costa Rica border, Route 17 across the Darien Isthmus of Panama, Route 23 crossing the Panama-Colombia border and Route 25 across the western tip of Colombia. The conventionally excavated routes are Route 10 west of the Panama Canal Zone and Route 14 along the alinement of the present canal. The engineering studies examine from a technical standpoint the feasibility of constructing these routes and estimate their costs. To accomplish this we have made conceptual designs for canals capable of transiting at least 40,000 vessels annually (and possibly several times that many) and of accommodating ships of up to 250,000 dwt in size. Thus, in terms of basic requirements, all alternatives - conventional and nuclear - have been made comparable. Beginning with the northernmost route, let us now consider the four nuclear alternatives. Route 8 is 137 miles in length. Its maximum elevations are slightly less than 800 feet in the Continental Divide and about 400 feet through the so-called Eastern Divide. The rock to be excavated is primarily volcanic tuff. It is readily apparent that

Classic and molecular cytogenetic analysis regarding human reactivity to beta radiation

International Nuclear Information System (INIS)

Usurelu Daniela; Radu Irina; Gavrila Lucian; Cimponeriu Danut; Apostol Pompilia; Ahmadi Elham

2007-01-01

Complete text of publication follows. One of the most important mutagen agents in developing different types of cancer is the action of ionizing radiation. The main events induced by irradiation are: chromosome breakage, chromosome rearrangements and genomic instability. The chromosomal aberrations are very useful biomarkers as intermediate end points in evaluating harmful biological effects of ionizing radiation. So, the main objectives of this work were: the study of human genome reactivity to beta radiation by classic microscopy; the study of the integrity/modification of the telomeres after irradiation and the analysis of the amplification of the RNA telomerase compound by FISH technique. Irradiations were performed at Electron Accelerators Laboratory, National Institute for Laser, Plasma and Radiation Physics, Magurele-Bucharest, Romania. The samples were irradiated using an ALIN 10 linear electron accelerator. ALIN 10 is a travelling wave type linac operating at 2.998 GHz, 6.5 MeV mean energy, with a 0.1 mm Al foil exit window. Improved Fricke, ferrous sulphate, cupric sulphate and sulphuric acid in triple distilled water dosimetry system has been used to perform preliminary dose measurements. The conventional Hungerford method on short-term cultures for 72 hrs was adapted for human chromosome investigation. The peripheral blood was collected from aged 27, healthy, non-smoker donor. The doses used to irradiate human blood cultures were: 4, 6, 8 and 10 Gy. The slides for optic microscopy were prepared by air-drying and stained with a 10% Giemsa solution. For FISH technique was used Chromosome In Situ Hybridization Kit. The probes were: one satellite probe - for revealing the telomere and the second one for the RNA telomerase compound. A large spectrum of chromosomal rearrangements was induced by beta irradiation in humans in vitro: complex chromosomal interchange involving at least two nonhomologous chromosomes, double minutes (DM), acentric fragments

Biogas conference on direct selling and financing in France and in Germany

International Nuclear Information System (INIS)

Furois, Timothee; Vollmer, Carla; Schlienger, Marc; Delagrandanne, Julien; Schwill, Jochen; Trommler, Marcus; Barchmann, Tino; Dotzauer, Martin; Durot, Alexandre; Ricordeau, Damien; Schuenemann-Plag, Peter; Wehner, Gustav; Wagner, Robert; Mestrel, Marc

2016-01-01

The French-German office for Renewable energies (OFAEnR) organised a conference on the regulatory context, direct selling and financing of methanation plants in France and in Germany. In the framework of this French-German exchange of experience, about 60 participants debated the following topics: direct selling impact on biogas industry, key-steps of methanation development in Germany, experience feedback of direct electricity selling and optimization of the production, banks experience feedback in methanation financing. This document brings together the available presentations (slides) made during this event: 1 - French support schemes for biogas (Timothee Furois); 2 - Development of the framework for biogas plants within the Renewable energy Sources Act from 2000 until 2015 (Carla Vollmer); 3 - Direct selling: challenges and opportunities (Marc Schlienger); 4 - The rules of the aggregator and electricity market (Julien Delagrandanne); 5 - Feed in Premium (FiP) with Biogas Power Plants, experiences in Germany (Jochen Schwill); 6 - Flexibilisation of biogas production - Impulses from EEG -legislation (Marcus Trommler); 7 - Bank approach in the direct selling approach (Alexandre Durot); 8 - Biogas Financing - Correlation between Return and Project Financing (Damien Ricordeau); 9 - Comparative economic analysis of various types of biogas plant Profitability of small and medium biogas plants on the basis of slurry and maize silage in Germany (Peter Schuenemann-Plag); 10 - experience feedback on important financing leviers (Gustav Wehner); 11 - Analysis of the different ways of methanation facilities financing (Robert Wagner); 12- The development of biogas project without recourse to purchase prices in France and Germany (Marc Mestrel)

Interest of corrective makeup in the management of patients in dermatology

Directory of Open Access Journals (Sweden)

Seité S

2012-09-01

Full Text Available S Seité,1 P Deshayes,2 B Dréno,3 L Misery,4 P Reygagne,5 P Saiag,6 F Stengel,7 AM Roguedas-Contios,4 A Rougier11La Roche-Posay Pharmaceutical Laboratories, Asnières, France; 2Service de Dermatologie, Caen, France; 3Hôtel-Dieu, Nantes, France; 4CHU de Brest-Hôpital Morvan, Brest, France; 5Centre Sabouraud, Hôpital Saint-Louis, Paris, France; 6CHU Ambroise Paré, Boulogne, France; 7Department of Dermatology, Buenos Aires, ArgentinaBackground: Disfiguring dermatoses may have a significant impact on patients’ quality of life, namely on their relationship with others, self image, and self esteem. Some previous studies have suggested that corrective foundation can improve the quality of life (QOL of patients with facial dermatoses; in particular, in patients with acne vulgaris or pigmentary disorders.Objective: The aim of this prospective study was to evaluate the impact of the skin conditions of patients with various skin diseases affecting their face (scars, acne, rosacea, melasma, vitiligo, hypo or hyperpigmentation, lentigines, etc on their QOL and the improvement afforded by the use of corrective makeup for 1 month after being instructed on how to use it by a medical cosmetician during an initial medical consultation.Methods: One hundred and twenty-nine patients with various skin diseases affecting the patients’ face were investigated. The patients were instructed by a cosmetician on how to use corrective makeup (complexion, eyes, and lips and applied it for 1 month. The safety of the makeup application was evaluated and the QOL was assessed via a questionnaire (DLQI and using a 10-cm visual analog scale (VAS completed before the first application and at the final visit. The amelioration of their appearance was documented by standardized photography.Results: No side effects occurred during the course of the study. A comparison of the standardized photographs taken at each visit showed the patients’ significant improvement in

Growth inhibition of rice (Oryza sativa L.) seedlings in Ga- and In-contaminated acidic soils is respectively caused by Al and Al+In toxicity.

Science.gov (United States)

Su, Jeng-Yan; Syu, Chien-Hui; Lee, Dar-Yuan

2018-02-15

Limited information exists on the effects of emerging contaminants gallium (Ga) and indium (In) on rice plant growth. This study investigated the effects on growth and uptake of Ga and In by rice plants grown in soils with different properties. Pot experiment was conducted and the rice seedlings were grown in two soils of different pH (Pc and Cf) spiked with various Ga and In concentrations. The results showed concentrations of Ga, In, and Al in soil pore water increased with Ga- or In-spiking in acidic Pc soils, significantly decreasing growth indices. According to the dose-response curve, we observed that the EC 50 value for Ga and In treatments were 271 and 390mgkg -1 in Pc soils, respectively. The context of previous hydroponic studies suggests that growth inhibition of rice seedlings in Ga-spiked Pc soils is mainly due to Al toxicity resulting from enhanced Al release through competitive adsorption of Ga, rather than from Ga toxicity. In-spiked Pc soils, both In and Al toxicity resulted in growth inhibition, while no such effect was found in Cf soils due to the low availability of Ga, In and Al under neutral pH conditions. Copyright © 2017 Elsevier B.V. All rights reserved.

Digital model evaluation of the predevelopment flow system of the Tertiary limestone aquifer, Southeast Georgia, Northeast Florida, and South South Carolina

Science.gov (United States)

Krause, Richard E.

1982-01-01

A computer model using finite-difference techniques was used successfully to simulate the predevelopment flow regime within the multilayered Tertiary limestone aquifer system in Southeastern Georgia, Northeastern Florida, and Southern South Carolina as part of the U.S. Geological Survey 's Tertiary Limestone Regional Aquifer System analysis. The aquifer, of early Eocene to Miocene age, ranges from thin interbedded clastics and marl in the updip area to massive limestone and dolomite 1,500 feet thick in the downdip area. The aquifer is confined above by Miocene clay beds, and terminates at depth in low-permeability rocks or the saltwater interface. Model-simulated transmissivity of the upper permeable zone ranged from about 1 x 10 super 3 foot squared per day in the updip area and within parts of the Gulf Trough (a series of alinement basins filled by fine clastic in material) to about 1 x 10 super 6 foot squared per day in South Georgia, and area having large secondarily developed solution channels. The model results indicate that only about 540 cubic feet per second of water flowed through the predeveloped system, from the updip highland area of high altitude and in the areas north of Valdosta and southwest of Jacksonville, to discharge along streams in the updip area and diffuse upward leakage in the downdip area near the coast and offshore. (USGS)

Rheoviscometric measurements on starch, flour and black pepper treated by electron-beam and microwaves

International Nuclear Information System (INIS)

Ferdes, O.S.; Tirlea, A.; Badea, M.; Casandroiu, T.; Oprita, N.

1998-01-01

Irradiation was performed with an ALIN-7 linac within the dose range of 0 to 16 kGy at a dose rate of approximately 1.5 kGy/min. The samples were accommodated in a cavity which was also used for the microwave treatment. The microwave irradiation was carried out inside a special designed system using a 2.45 GHz CW magnetron of 850 W maximum output power. The samples were treated using various power values for irradiation periods varying between 10 and 120 s. Combined treatment by both methods was also applied. The rheoviscometric measurements were carried out on gelified suspensions of starch, flour and black pepper in equivalent starch concentration conditions. For the black pepper suspensions the pH value was adjusted to more than 12 units by adding 33 % NaOH solution. The effects of electromagnetic field and irradiation on starch, flour and pepper were described in terms of apparent viscosity and shear stress. All the samples investigated exhibited similar rheoviscometric behaviour, which can be attributed to starch degradation caused by microwave and electron-beam irradiation, the latter having a more significant effect on the rheological properties. Some consideration were also made concerning the thermal and non-thermal effects of microwaves and of the combined (e-beam and microwave) treatments of starch, flour and pepper

CONSIDERATIONS REGARDING EUROJUST'S CONTRIBUTION IN FIGHTING CROSS-BORDER CRIME IN EUROPE

Directory of Open Access Journals (Sweden)

Ion, MIHALCEA

2014-11-01

Full Text Available One of the objectives of the European Union enshrined in 67 alin.(1 (ex-art. 61 TCE and ex-art. 29 TUE of the consolidated version of the Treaty on European Union is to create a common European space of security and justice without internal frontiers, in which to ensure the free movement of people, corralated with appropriate measures on external border controls , asylum , immigration, and crime prevention and combating. This is a long term goal that requires active cooperation of Member States and multiple efforts by EU institutions. The institutional functioning practice has shown that the clasic forms of judicial cooperation do not have the ability to complete this objective and that is necessary to create specialized structures. In this context the First European institutional structure was established in 2002, a specialized agency of the European Union, named Eurojust, with the main objective to promote and improve coordination and cooperation between the judicial authorities of the Member States in the fight against serious cross-border crime affecting the European Union. Tasks of Eurojust and relations with other European bodies, particularly the Council and Commission are established by Decision 2002/187 / JHA amended by Decision 2009/426 / JHA Council of 16 December 2008 It is exercised by College Eurojust or through its national members.

Involvement of clip-domain serine protease in the anti-Vibrio immune response of abalone (Haliotis discus hannai)-Molecular cloning, characterization and functional analysis.

Science.gov (United States)

Hu, Jian-Jian; Chen, Yu-Lei; Duan, Xue-Kun; Jin, Teng-Chuan; Li, Yue; Zhang, Ling-Jing; Liu, Guang-Ming; Cao, Min-Jie

2018-01-01

Vibrio parahemolyticus (V. parahemolyticus) is a major pathogen for abalone, an important economical shellfish in coastal area of China. There is little known about the abalone innate immune system against pathogen infection. Clip-domain serine proteases (cSPs) are increasingly recognized to play important roles in host immune defense in invertebrates. In this study, we cloned a cSP (Hdh-cSP) from abalone (Haliotis discus hannai). We found out that Hdh-cSP was widely expressed in multiple tissues of abalone, with highest level in the immune-like organ, hepatopancreas. V. parahemolyticus infection induced significantly elevated expression of Hdh-cSP in addition to better-characterized innate immune component genes including Rel/NF-κB, allograft inflammatory factor (ALInFa), macrophage expressed protein (MEP) and caspase-8. Importantly, the silencing of Hdh-cSP reduced the expression of these genes, suggesting that Hdh-cSP was an upstream regulatory factor in V. parahemolyticus infection. Further analysis showed that apoptosis of hemocytes was inhibited when the transcription of Hdh-cSP was knocked down, suggesting that Hdh-cSP participated in cell apoptosis by regulation of caspase 8 expression in V. parahemolyticus infection. Therefore, our study established an important role of cSP in the innate immunity against V. parahemolyticus infection in abalone. Copyright © 2017 Elsevier Ltd. All rights reserved.

Relativistic wave equations and compton scattering

International Nuclear Information System (INIS)

Sutanto, S.H.; Robson, B.A.

1998-01-01

Full text: Recently an eight-component relativistic wave equation for spin-1/2 particles was proposed.This equation was obtained from a four-component spin-1/2 wave equation (the KG1/2 equation), which contains second-order derivatives in both space and time, by a procedure involving a linearisation of the time derivative analogous to that introduced by Feshbach and Villars for the Klein-Gordon equation. This new eight-component equation gives the same bound-state energy eigenvalue spectra for hydrogenic atoms as the Dirac equation but has been shown to predict different radiative transition probabilities for the fine structure of both the Balmer and Lyman a-lines. Since it has been shown that the new theory does not always give the same results as the Dirac theory, it is important to consider the validity of the new equation in the case of other physical problems. One of the early crucial tests of the Dirac theory was its application to the scattering of a photon by a free electron: the so-called Compton scattering problem. In this paper we apply the new theory to the calculation of Compton scattering to order e 2 . It will be shown that in spite of the considerable difference in the structure of the new theory and that of Dirac the cross section is given by the Klein-Nishina formula

Bulk division of metallogenetic region and uranium metallogenetic regularities in Heilongjiang basin and its adjacent areas

International Nuclear Information System (INIS)

Guo Hua; Zhao Fengmin; Hu Shaokang; Chen Zuyi

2002-01-01

On the base of the study in the working area, a conclusion is made that there are 36 combined types of tectonic-material and 6 basic tectonic units. According to radioactive geochemical quantitative and qualitative factors, which are relevant to rock composition and geological formation, 5 radioactive geochemical provinces and 8 radioactive geochemical differentiation regions could be marked out. The working area contains three hydrogeological fold belts and two hydrogeological artesian basins. It could also be divided into 9 metallogenetic provinces or 30 metallogenetic regions, or 206 ore districts. On the other hand, the area could be divided into 2 uranium metallogenetic provinces, 2 potential uranium metallogenetic provinces and 3 uraniferous provinces, which contain uranium properties or potential uranium properties or uraniferous properties. The authors systematically summary the geological environment and indicators of prospecting and predicting of fluorine-molybdenum-uranium formation, hydromorphic uranium deposit formation and poly-genetic uranium deposit formation which contains uranium-coal model, uranium-asphalt model, uranium-sulfuret model, etc. The metallogenetic potential among Aerdan uranium province, Aoliaokema uranium province, Bulieya-Jiamusi-Xingkai potential uranium province and Xihuote-Alin uranium province are assessed. On this base, the authors delineate 23 uranium metallogenetic prospective areas needing further exploration efforts. 8 uranium metallogenetic prospective areas in China are marked out, which are areas of interest for searching for exogenetic and epigenetic sandstone uranium deposits

An interdisciplinary analysis of multispectral satellite data for selected cover types in the Colorado Mountains, using automatic data processing techniques. [geological lineaments and mineral exploration

Science.gov (United States)

Hoffer, R. M. (Principal Investigator)

1974-01-01

The author has identified the following significant results. One capability which has been recognized by many geologists working with space photography is the ability to see linear features and alinements which were previously not apparent. To the exploration geologist, major lineaments seen on satellite images are of particular interest. A portion of ERTS-1 frame 1407-17193 (3 Sept. 1973) was used for mapping lineaments and producing an iso-lineament intersection map. Skylab photography over the area of prime area was not useable due to snow cover. Once the lineaments were mapped, a grid with 2.5 km spacing was overlayed on the map and the lineament intersections occurring within each grid square were counted and the number plotted in the center of the grid square. These numbers were then contoured producing a contour map of equal lineament intersection. It is believed that the areas of high intersection concentration would be the most favorable area for ore mineralization if favorable host rocks are also present. These highly fractured areas would act as conduits for carrying the ore forming solutions to the site of deposition in a favorable host rock. Two of the six areas of high intersection concentration are over areas of present or past mining camps and small claims are known to exist near the others. These would be prime target areas for future mineral exploration.

MODALITĂŢI DE EXPRIMARE A ACŢIUNII DE TRAFIC DE PERSOANE ÎN DREPTUL COMPARAT

Directory of Open Access Journals (Sweden)

Mihai ŞTEFĂNOAIA

2015-11-01

Full Text Available În prezentul articol autorul urmăreşte să ofere, prin metoda dreptului comparat, soluţii mai bune, specifice, relevante procesului legislativ în interpretarea infracţiunii de trafic de persoane. Obiectul de cercetare al lucrării îl formează urmă-toarele subiecte: conceptul şi natura traficului de persoane; recrutarea, primirea, adăpostirea, ascunderea, transportarea, transferul sau acceptarea persoanelor în vederea exploatării acestora; factorii care contribuie la dezvoltarea traficului de persoane; problemele prevenirii şi combaterii traficului de persoane; instrumentele juridice internaţionale de prevenire şi combatere a traficului de persoane etc. În calitate de suport la elaborarea prezentului demers ştiinţific a servit legislaţia penală a diferitelor state, o atenţie specială fiind acordată următoarelor articole: art.165 „Traficul de fiinţe umane” şi art.206 „Traficul de copii” din Codul penal al Republicii Moldova; art.210 „Traficul de persoane” şi art.211 „Traficul de minori” din Codul penal al României din 2009; alin.1 art.1 al Legii Arabiei Saudite din 2009 cu privire la combaterea traficului de persoane; alin.(1 art.1 al Legii Ghanei din 2005 cu privire la combaterea traficului de persoane; art.2 al Legii Mauritiusului din 2009 cu privire la combaterea traficului de persoane; art.3 din Protocolul la Convenţia ONU din 15.11.2000: recrutarea, transportarea, transferul, adăpostirea şi primirea victimei; Convenţia Consiliului Europei privind lupta împotriva traficului de fiinţe umane, adoptată la 03.05.2005 etc.EXPRESSIONS OF THE ACT OF HUMAN TRAFFICKING WITHIN THE COMPARATIVE LAWThis article seeks, by the method of comparative law to provide better solutions, specific, relevant to the legislative process in the interpretation of the offence of human trafficking. The object of this research was formed by the following topics: the concept and nature of human trafficking; the recruitment

The factory as a battlefield

Directory of Open Access Journals (Sweden)

Helena Chávez Mac Gregor

Full Text Available The crisis of labour is also one of representation. Some contemporary artists working with moving images have been questioning how to represent capital, labour and the worker. Isaac Julien or Harun Farocki, for example, have focused on interlacing characters - from fiction or reality - with geopolitical spaces in order to present the entanglement of the economical new order with the new forms of labour. The South African artist Simon Gush has shifted from this trend in order to present labour without directly representing the workers. In his artwork there is no longer a search for the political subject as a historical force or for the individuals who occupied its place; instead he leads viewers to a critical reading of an object, allowing a staging of the past from the viewpoint of the present. That is what I think Red does. In this article I explore Gush's connections with Marx, Benjamin and Steyerl to show how Gush's work is part of a critical tradition that has abandoned the subject as the privileged instance of political agency; turning the emphasis of the modern schema upside down, it focuses on the object as the force of emancipation. I would like to suggest that Gush used an object, Mandela's red Mercedes-Benz, to produce another image so that the story told is not necessarily that of a symbol of pacification, but one in which the factory was a battlefield. In this way I explore the emancipatory potencies of the object. What I propose is a reading of Red from the point of view of a return to the thing, where the latter becomes a political force.

Professor André Jouve (1909-2001): A French cardiologist who was a pioneer of clinical vector-electrocardiography and cardiovascular epidemiology.

Science.gov (United States)

Puddu, Paolo Emilio

2016-01-01

André, Julien, Auguste Jouve was born in Marseilles on June 10, 1909 son of Xavier Marie Francois Louis Jouve MD and Marie Louise Charlotte Vigliengo his wife. He had a brilliant medical career in Marseilles: Resident at Marseilles Hospitals in 1931, major of his promotion, then an Assistant in 1943 and a Chief in 1951, to become Associate Professor of Medicine in 1946 and finally Full Professor of Clinical and Experimental Cardiology in 1954. Fellow of several Cardiological Societies, he became President of the French Society of Cardiology in 1968, Vice-President of the European Society of Cardiology in 1972 and finally President of the French College of Vascular Pathology in 1973. He had been a WHO Expert for degenerative and cardiovascular diseases from 1958 to 1981 and a National correspondent of the Academy of Medicine in 1977. He was decorated by the Légion d'Honneur (Officer in 1975). He retired in 1981 and died in 2001. Clinical vector-electrocardiology and cardiovascular epidemiology were the main areas of his interest where he made essential contributions such as the famous treatise on ECG. The Heart Cantini Center was considered his leading creation and action, where the first French heart transplantation was performed in 1968, the first French epidemiological investigation on coronary risk factors took place, the idea of starting prevention at pediatric age was clearly outlined and the need of concentrating on psychological and dysmetabolic factors was precisely advocated for indexing later development of ischemic heart diseases. These achievements are reviewed and put into perspective. Copyright © 2016 Elsevier Inc. All rights reserved.

Presentations given at the two Enerplan solar conferences during the renewable energy workshop on February 21-22, 2013

International Nuclear Information System (INIS)

Gouranton, Germain; Patte, Emmanuelle; Damian, Jean; Guiguet, Antoine; Benabdelkarim, Mohamed; Darragon, Adrien; Genin, Pierre; Persem, Melanie; Loyen, Richard; Gay, Philippe; Gossement, Arnaud; Joffre, Andre; Mugnier, Daniel; Korniloff, Amaury; Mueth, Thierry; Delagrandanne, Julien; Cardonnel, Christian; Aubert, Elisabeth; Carl, Yves; Chastanet, Aymeric; Jean, Andre; Laplagne, Valerie; Parrens, Gael; Laurentin, Emmanuel; Mouterde, Jerome

2013-02-01

At the occasion of the 2013 Renewable energy workshop, Enerplan, the French union of solar energy professionals, organized two conferences on photovoltaic power generation and on solar heating. This document brings together the presentations given at these conferences: 1 - The road-map of the positive energy building, lessons learnt from experience feedbacks to anticipate the legal requirements (Germain Gouranton, Emmanuelle Patte); 2 - Qualitative requirements to fulfil commitments and responsibilities in the building industry (Jean Damian, Antoine Guiguet); 3 - Hybrid heat and PV systems with air or water (Mohamed Benabdelkarim, Adrien Darragon); 4 - German feedback about the photovoltaic self-consumption market (Pierre Genin, Melanie Persem); 5 - Photovoltaic self-consumption market as a possible engine of growth for France and its legal framework (Richard Loyen, Arnaud Gossement); 6 - Supportive solar project of citizen self-consumption in Perpignan (Andre Joffre); 7 - Long-term supply contract for local suppliers or big consumers, experience feedback and perspectives (Amaury Korniloff, Thierry Mueth, Julien Delagrandanne); 8 - 2012 thermal regulations for buildings, HPE, THPE labels and positive energy buildings: legal framework and impact on efficiency (Christian Cardonnel, Elisabeth Aubert); 9 - From individual to collective solar heating: evolution of the industrial offer and competitiveness (Yves Carl, Aymeric Chastanet, Andre Jean); 10 - Design-Realisation-Exploitation-Maintenance and efficiency warranty in collective solar heating, recommendations and tools from the SOCOL professional initiative (Philippe Gay, Daniel Mugnier); 11 - The optimized individual solar water heater (Valerie Laplagne); 12 - The 100% renewable offer for hot water thanks to the solar heat and wood-fuel combination (Gael Parrens); 13 - Maintenance issues: opportunities and responsibilities (Emmanuel Laurentin); 14 - Hybrid heat and PV systems with air or water (Mohamed

The world of targeted therapies in kidney cancers: pitfalls, tips and tricks

Directory of Open Access Journals (Sweden)

Vallard A

2017-03-01

Full Text Available Alexis Vallard, Jane-Chloé Trone, Julien Langrand-Escure, Sophie Espenel, Jean-Baptiste Guy, Chloé Rancoule, Yaoxiong Xia, Anis El Meddeb Hamrouni, Majed Ben Mrad, Nicolas Magné Department of Radiation Oncology, Lucien Neuwirth Cancer Institute, Saint-Priest en Jarez, France Abstract: In the past few years, metastatic renal cell carcinoma prognosis was improved by the development of molecular targeted therapies (TTs. At the metastatic stage, the tolerance to treatment is a major concern, not only because of the challenge of the efficacy/toxicity ratio improvement but also because of the importance of an optimal adherence to oral treatments. The present case series relates the issues of dealing with uncommon and sometimes never described side effects of sunitinib and sorafenib. The first case report deals with grade 3 vomiting during hemodialysis with concurrent administration of sunitinib. The second case is an iterative gout attack induced by sunitinib. The third case presents a grade 3 scalp dysesthesia with sorafenib. The fourth case includes an astonishing efficacy of metronomic (ie, low doses during a long period of time bevacizumab in monotherapy. Multidisciplinary management and systematic reporting of unexpected efficacies and toxicities are needed to better understand TTs real therapeutic index. Although TTs revolutionized metastatic renal cell cancer prognosis, they also brought about previously unknown side effects. Identification and management of these off-target effects may be tricky, and therefore, comedication must be wisely chosen. As the physiopathology of these side effects is still unclear, multidisciplinary management and systematic reporting of toxicities are essential. Keywords: renal cell carcinoma, bevacizumab, sunitinib, sorafenib, toxicity, efficacy

Steppe bison paleobiology through the scope of stable isotopes and zooarchaeology

Science.gov (United States)

Julien, Marie-Anne; Dorothée, Drucker; Hervé, Bocherens; Ariane, Burke; Marylène, Patou-Mathis; Alexandra, Krotova

2010-05-01

Bison are one of the most abundant and widely distributed species of large mammal during the Late Pleistocene. In the southern steppes of Eastern Europe, steppe bison (Bison priscus) is ubiquitous in zooarchaeological assemblages, particularly during the Upper Palaeolithic when a model of economic "specialization" is proposed. Specialization, in this context, implies the deliberate selection of a preferred species, which becomes the key food resource. The applicability of a specialised hunting model for the Upper Palaeolithic of Europe has recently been challenged, however (Grayson & Delpech 2002). In this research, therefore we re-examine bison acquisition strategies during the Upper Palaeolithic in the Ukrainian steppes in the light of biogeochemical and zooarchaeological data. The acquisition strategies used to procure a prey species are directly related to its social and spatial behaviour. A synthesis of ethological information for contemporary bison (Julien 2009) demonstrates the behavioural diversity of this taxa, linked mainly to local environmental variability, climatic conditions and population density. It is therefore necessary to propose a paleoethological model for the steppe bison before attempting to identify the acquisition strategies used by prehistoric hunters. In this research, we reconstruct the behaviour of the steppe bison using a combination of zooarchaeological tools, stable isotope analysis (intra-tooth isotope variation of carbon, oxygen and strontium ratios) and traditional paleobiological approaches. The advantages of using a combined approach are demonstrated through the examination of a case study: the site of Amvrosievka (Ukraine). Amvrosievka is a complex of Epigravettian sites composed of a camp and kill site, where more than 500 bison are represented (Krotova & Belan 1993). Twenty-five permanent lower teeth (M3) representing twenty-five individual bison were selected from the kill and camp site for isotopic analysis. Intra- and

La Déclaration Universelle des Droits de l’Homme comme l’expression d’une vision du monde : une approche topique et génétique The Universal Declaration of Human Rights as an expression of a “vision of the world”: a topical and genetic perspective

Directory of Open Access Journals (Sweden)

Emmanuel de Jonge

2010-04-01

Full Text Available Dans cet article, je réalise une analyse de la Déclaration Universelle des Droits de l’Homme dans une perspective rhétorique et génétique. A l’aide des comptes rendus des débats préliminaires du Comité de Rédaction de la Déclaration, je montre que le texte a pour arrière-plan la volonté de fonder une vision du monde nouvelle, dans laquelle tout serait mis en œuvre d’un point de vue juridique, éthique, philosophique et psychologique pour que les actes subis par les populations européennes durant la Seconde Guerre Mondiale ne puissent plus se reproduire. Pour ce faire, j’analyse la question de l’expression linguistique des valeurs dans les deux premiers alinéas du préambule de la Déclaration.In this contribution, I analyze the text of the Universal Declaration of Human Rights from a rhetorical and genetic perspective. Starting from the summary reports of the Declaration Drafting Committee, I try to show that what lies at the background of the text is the feeling that the sufferings of WWII never can be reproduced. The drafters thus founded a new “vision of the world” that has shaped our values since then. I concentrate specifically on the first two lines of the preamble of the Declaration in order to analyze how the values are expressed linguistically in these paragraphs.

MiR-200a is involved in rat epididymal development by targeting β-catenin mRNA

Institute of Scientific and Technical Information of China (English)

Xiaojiang Wu; Botao Zhao; Wei Li; Yue Chen; Ruqiang Liang; Lin Li; Youxin Jin; Kangcheng Ruan

2012-01-01

The expression of 350 microRNAs (miRNAs) in epididymis of rat from postnatal development to adult (from postnatal days 7-70) was profiled with home-made miRNA microarray.Among them,48 miRNAs changed significantly, in which the expression of miR-200a increased obviously with time,in a good agreement with that obtained from northern blot analysis.The real-time quantitative-polymerase chain reaction result indicated that temporal expression of rat β-catenin was exactly inversed to that of miR-200a during rat epididymal development,implying that miR-200a might also target β-catenin mRNA in rat epididymis as reported by Saydam et al.in humans.The bioinformatic analysis indicated that 3' untranslated region of rat β-catenin mRNA did contain a putative binding site for miR-200a.Meanwhile,it was found that the sequence of this binding site was different from that of human β-catenin mRNA with a deletion of two adjacent nucleotides (U and C).But the results of luciferase targeting assay in HEK 293T cells and the overexpression of miR-200a in rat NRK cells demonstrated that miR-200a did target rat β-catenin mRNA and cause the suppression of its expression.All these results show that miR-200a should be involved in rat epididymal development by targeting β-catenin mRNA of rat and suppressing its expression.

[Diagnosis of pulmonary hemorrhage of the newborn infants using lung ultrasonography].

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Liu, J; Fu, W; Chen, S W; Wang, Y

2017-01-02

Objective: To investigate the accuracy and reliability of lung ultrasound in diagnosis of pulmonary hemorrhage of the newborn infants. Method: From January 2014 to May 2016, 142 neonates from the Army General Hospital of the Chinese PLA were enrolled in the study. They were divided into two groups: a study group of 42 neonates, who were diagnosed with pulmonary hemorrhage according to their medical history, clinical manifestations and chest X-ray findings, and a control group of 100 neonates with no lung disease. All subjects underwent bedside lung ultrasound in a quiet state in a supine, lateral or prone posture, performed by a single experienced physician. The ultrasound findings were compared between the two groups.Fisher's exact test was uesd for comparison between two groups. Result: The lung ultrasound main findings associated with pulmonary hemorrhage included: (1) Shred sign: which was seen in 40 patients(95%). (2) Lung consolidation with air bronchograms: which were seen in 35 patients(83%). (3) Pleural effusion: which was seen in 34 infants(81%), pleurocentesis confirmed that the fluid was really bleeding.(4)Atelectasis: which was seen in 14 cases(33%). (5) Pleural line abnormalities and disappearing A-lines with an incidence of 100%. (6) Alveolar-interstitial syndrome: 5 patients(12%)had the main manifestations of alveolar-interstitial syndrome. The above signs were not seen in normal controls (all P hemorrhage, which is suitable for routine application for the diagnosis of pulmonary hemorrhage in the neonatal intensive care unit.

Sinkhole development resulting from ground-water withdrawal in the Tampa area, Florida

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Sinclair, William C.

1982-01-01

The area of municipal well fields on the Gulf Coastal Plain north of tampa, Fla., is densely pitted with natural sinkholes and sinkhole lakes that have resulted from collapse of surficial sand and clay into solution cavities in the underlying carbonate rocks of the Floridan aquifer. Although solution of the underlying rocks is the ultimate cause of sinkholes, some have been induced by abrupt changes in ground-water levels caused by pumping. Declines in water levels cause loss of support to the bedrock roofs over cavities and to surficial material overlying openings in the top of bedrock. The volume of calcium, magnesium , and carbonate (the constituents of limestone and dolomite) in solution in the water withdrawn from four well fields near Tampa totaled about 240,000 cubic feet in 1978. Most induced solution takes place at the limestone surface however, and the area of induced recharge is so extensive that the effect of induced limestone solution on sinkhole development is negligible. Alinement of established sinkholes along joint patterns in the bedrock suggests that a well along these lineations might have direct hydraulic connection with a zone of incipient sinkholes. Therefore, pumping of large-capacity wells along such lineations would increase the probability of sinkhole development. Although sinkholes generally form abruptly in the study area, local changes such as vegetative stress, ponding of rainfall, misalinement of structures, and turbidity in well water are all indications that percollapse subsidence may be taking place. (USGS)

An X-ray beam position monitor based on the photoluminescence of helium gas

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Revesz, Peter; White, Jeffrey A.

2005-03-01

A new method for white beam position monitoring for both bend magnet and wiggler synchrotron X-ray radiation has been developed. This method utilizes visible light luminescence generated as a result of ionization by the intense X-ray flux. In video beam position monitors (VBPMs), the luminescence of helium gas at atmospheric pressure is observed through a view port using a CCD camera next to the beam line. The beam position, profile, integrated intensity and FWHM are calculated from the distribution of luminescence intensity in each captured image by custom software. Misalignment of upstream apertures changes the image profile making VBPMs helpful for initial alignment of upstream beam line components. VBPMs can thus provide more information about the X-ray beam than most beam position monitors (BPMs). A beam position calibration procedure, employing a tilted plane-parallel glass plate placed in front of the camera lens, has also been developed. The accuracy of the VBPM system was measured during a bench-top experiment to be better than 1 μm. The He-luminescence-based VBPM system has been operative on three CHESS beam lines (F hard-bend and wiggler, A-line wiggler and G-line wiggler) for about a year. The beam positions are converted to analog voltages and used as feedback signals for beam stabilization. In our paper we discuss details of VBPM construction and describe further results of its performance.

An appraisal of golimumab in the treatment of severe, active nonradiographic axial spondyloarthritis

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Paccou J

2016-07-01

Full Text Available Julien Paccou, René-Marc Flipo Department of Rheumatology, Lille University Hospital, Lille, France Abstract: Golimumab (Simponi® is a fully human tumor necrosis factor α inhibitor (TNFi antibody administered subcutaneously. In the European Union, golimumab is indicated for the treatment of adults with severe, active axial spondyloarthritis (axSpA, which includes both ankylosing spondylitis (AS and nonradiographic axSpA (nr-axSpA. In the US, it is indicated for the treatment of adults with active AS only. This article reviews the efficacy and tolerability of golimumab in nr-axSpA patients compared to other TNFi agents (adalimumab, infliximab, etanercept, and certolizumab pegol. In one ongoing, well-designed controlled study (GO-AHEAD, data at 16 weeks showed that treatment with golimumab (50 mg every 4 weeks was effective in improving the clinical signs and symptoms of disease in nr-axSpA patients. In addition, 16 weeks of treatment with golimumab reduced inflammation in the sacroiliac joints and spine in patients with nr-axSpA. Moreover, objective evidence of active inflammation at baseline, such as a positive magnetic resonance imaging scan and/or an elevated CRP level, was a good predictor of treatment response to golimumab. Golimumab was generally well tolerated in this study, with a tolerability profile consistent with that seen in previous clinical trials for other indications. Although additional long-term data are needed, current evidence indicates that golimumab is an effective option for the treatment of nr-axSpA. However, in the absence of comparative head-to-head trials, there is no recommended hierarchy for the first prescription of a TNFi agent for the treatment of either nr-axSpA or AS. Keywords: axial spondyloarthritis, nonradiographic axial spondyloarthritis, ankylosing spondylitis, golimumab, tumor necrosis factor α inhibitor, therapy

Reduction in Fall Rate in Dementia Managed Care Through Video Incident Review: Pilot Study.

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Bayen, Eleonore; Jacquemot, Julien; Netscher, George; Agrawal, Pulkit; Tabb Noyce, Lynn; Bayen, Alexandre

2017-10-17

Falls of individuals with dementia are frequent, dangerous, and costly. Early detection and access to the history of a fall is crucial for efficient care and secondary prevention in cognitively impaired individuals. However, most falls remain unwitnessed events. Furthermore, understanding why and how a fall occurred is a challenge. Video capture and secure transmission of real-world falls thus stands as a promising assistive tool. The objective of this study was to analyze how continuous video monitoring and review of falls of individuals with dementia can support better quality of care. A pilot observational study (July-September 2016) was carried out in a Californian memory care facility. Falls were video-captured (24×7), thanks to 43 wall-mounted cameras (deployed in all common areas and in 10 out of 40 private bedrooms of consenting residents and families). Video review was provided to facility staff, thanks to a customized mobile device app. The outcome measures were the count of residents' falls happening in the video-covered areas, the acceptability of video recording, the analysis of video review, and video replay possibilities for care practice. Over 3 months, 16 falls were video-captured. A drop in fall rate was observed in the last month of the study. Acceptability was good. Video review enabled screening for the severity of falls and fall-related injuries. Video replay enabled identifying cognitive-behavioral deficiencies and environmental circumstances contributing to the fall. This allowed for secondary prevention in high-risk multi-faller individuals and for updated facility care policies regarding a safer living environment for all residents. Video monitoring offers high potential to support conventional care in memory care facilities. ©Eleonore Bayen, Julien Jacquemot, George Netscher, Pulkit Agrawal, Lynn Tabb Noyce, Alexandre Bayen. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 17.10.2017.

An analysis of bedload and suspended load interactions

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Recking, alain; Navratil, Oldrich

2013-04-01

Several approaches were used to develop suspension equations. It includes semi-theoretical equations based on the convection diffusion equation (Einstein 1950; Van Rijn 1984; Camenen and Larson 2008; Julien 2010), semi-empirical tools based on energy concept (Velikanov 1954; Bagnold 1966), empirical adjustments (Prosser and Rusttomji 2000). One essential characteristic of all these equations is that most of them were developed by considering continuity between bedload and suspended load, and that the partitioning between these two modes of transport evolves progressively with increasing shear stress, which is the case for fine bed materials. The use of these equations is thus likely to be welcome in estuaries or lowland sandy rivers, but may be questionable in gravel-bed rivers and headwater streams where the bed is usually structured vertically and fine sediments potentially contributing to suspension are stored under a poorly mobile surface armour comprising coarse sediments. Thus one question this work aimed to answer is does the presence of an armour at the bed surface influence suspended load? This was investigated through a large field data set comprising instantaneous measurements of both bedload and suspension. We also considered the river characteristics, distinguishing between lowland rivers, gravel bed rivers and headwater streams. The results showed that a correlation exist between bedload and suspension for lowland and gravel bed rivers. This suggests that in gravel bed rivers a large part of the suspended load is fed by subsurface material, and depends on the remobilization of the surface material. No correlation was observed for head water streams where the sediment production is more likely related to hillslope processes. These results were used with a bedload transport equation for proposing a method for suspended load estimate. The method is rough, but especially for gravel bed rivers, it predicts suspended load reasonably well when compared to

Didactique du français langue étrangère et seconde dans une perspective plurilingue et pluriculturelle en hommage à la professeure Dr. Aline Gohard-Radenkovic

CERN Document Server

Blons-Pierre, Catherine

2016-01-01

La Didactique du FLE/FLS dans une perspective plurilingue et pluriculturelle définit et délimite la place du FLE et des échanges francophones dans les sociétés plurilingues et pluriculturelles actuelles. Elle propose les fondamentaux de la didactique, une réflexion sur les contextes d'enseignement et les aspects socio-culturels du FLE/FLS.

Tethered capsule OCT endomicroscopy: from bench to bedside at the primary care office (Conference Presentation)

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Gora, Michalina J.; Simmons, Leigh H.; Tiernan, Aubrey R.; Grant, Catriona N.; Soomro, Amna R.; Walker Corkery, Elizabeth S.; Rosenberg, Mireille; Metlay, Joshua P.; Tearney, Guillermo J.

2016-03-01

We have developed a swallowable tethered capsule OCT endomicroscopy (TCE) device that acquires microscopic images of the entire esophagus in unsedated subjects in a quick and comfortable procedure. To test its capabilities of TCE to become a population-based screening device, we conducted a clinical feasibility study in the primary care office. The swept-source OCT imaging system (1310nm central wavelength, 40kHz A-line rate, 10um axial resolution) together with the tethered capsule catheter (11x25mm capsule attached to a flexible tether) were transferred to the PCP office where unsedated patients scheduled for non-urgent PCP visits swallowed the capsule and microscopic OCT images of the entire esophagus were collected. After the whole length of the esophagus was imaged, the catheter was disinfected for reuse. Twenty subjects were enrolled in the study, including nine female and eleven male. All TCE procedures were performed by a nurse and lasted in average 5:42 ± 1:54 min. High-resolution images of the esophagus were obtained in all seventeen subjects that swallowed the capsule. Our clinical experience in this cohort, subject feedback, image quality, and technological adaptations for efficient utilization in this setting will be presented. The ease and simplicity of the procedure combined with high quality of the images demonstrate the potential for this technology to become a population-based screening device. Technology limitations and future development guided by findings from this initial experience will be discussed with the goal of effectively translating TCE to the outpatient primary care setting.

High speed all optical shear wave imaging optical coherence elastography (Conference Presentation)

Science.gov (United States)

Song, Shaozhen; Hsieh, Bao-Yu; Wei, Wei; Shen, Tueng; O'Donnell, Matthew; Wang, Ruikang K.

2016-03-01

Optical Coherence Elastography (OCE) is a non-invasive testing modality that maps the mechanical property of soft tissues with high sensitivity and spatial resolution using phase-sensitive optical coherence tomography (PhS-OCT). Shear wave OCE (SW-OCE) is a leading technique that relies on the speed of propagating shear waves to provide a quantitative elastography. Previous shear wave imaging OCT techniques are based on repeated M-B scans, which have several drawbacks such as long acquisition time and repeated wave stimulations. Recent developments of Fourier domain mode-locked high-speed swept-source OCT system has enabled enough speed to perform KHz B-scan rate OCT imaging. Here we propose ultra-high speed, single shot shear wave imaging to capture single-shot transient shear wave propagation to perform SW-OCE. The frame rate of shear wave imaging is 16 kHz, at A-line rate of ~1.62 MHz, which allows the detection of high-frequency shear wave of up to 8 kHz. The shear wave is generated photothermal-acoustically, by ultra-violet pulsed laser, which requires no contact to OCE subjects, while launching high frequency shear waves that carries rich localized elasticity information. The image acquisition and processing can be performed at video-rate, which enables real-time 3D elastography. SW-OCE measurements are demonstrated on tissue-mimicking phantoms and porcine ocular tissue. This approach opens up the feasibility to perform real-time 3D SW-OCE in clinical applications, to obtain high-resolution localized quantitative measurement of tissue biomechanical property.

A parallelizable real-time motion tracking algorithm with applications to ultrasonic strain imaging

International Nuclear Information System (INIS)

Jiang, J; Hall, T J

2007-01-01

Ultrasound-based mechanical strain imaging systems utilize signals from conventional diagnostic ultrasound systems to image tissue elasticity contrast that provides new diagnostically valuable information. Previous works (Hall et al 2003 Ultrasound Med. Biol. 29 427, Zhu and Hall 2002 Ultrason. Imaging 24 161) demonstrated that uniaxial deformation with minimal elevation motion is preferred for breast strain imaging and real-time strain image feedback to operators is important to accomplish this goal. The work reported here enhances the real-time speckle tracking algorithm with two significant modifications. One fundamental change is that the proposed algorithm is a column-based algorithm (a column is defined by a line of data parallel to the ultrasound beam direction, i.e. an A-line), as opposed to a row-based algorithm (a row is defined by a line of data perpendicular to the ultrasound beam direction). Then, displacement estimates from its adjacent columns provide good guidance for motion tracking in a significantly reduced search region to reduce computational cost. Consequently, the process of displacement estimation can be naturally split into at least two separated tasks, computed in parallel, propagating outward from the center of the region of interest (ROI). The proposed algorithm has been implemented and optimized in a Windows (registered) system as a stand-alone ANSI C++ program. Results of preliminary tests, using numerical and tissue-mimicking phantoms, and in vivo tissue data, suggest that high contrast strain images can be consistently obtained with frame rates (10 frames s -1 ) that exceed our previous methods

Evidence for differences between B. bruxellensis strains originating from an enological environment

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Vincent Renouf

2009-03-01

Full Text Available Vincent Renouf1,2, Cécile Miot-Sertier2, Marie-Claire Perello2, Gilles de Revel2, Aline Lonvaud-Funel21Laffort, Bordeaux, France; 2UMR Œnologie, INRA-Université Bordeaux, FranceAbstract: The aim of this paper is to study and compare the physiological diversity of different strains of a wine spoilage yeast species: Brettanomyces bruxellensis. The minimum inhibitory concentrations of several drugs on different B. bruxellensis strains were scored on solid nutrient media. This revealed variations in resistance among the B. bruxellensis strains. Their capacity to develop in different wine and must environments: pH, ethanol, and SO2 concentrations, were evaluated by measuring the direct incubation survival rate. The results, compared with those obtained for other wine yeast species, confirmed the remarkable resistance of B. bruxellensis strains to various conditions which inhibit the growth of other species. Nevertheless some differences were observed among the B. bruxellensis strains, thus confirming their physiological diversity. A comparison of their volatile phenol production revealed intraspecific heterogeneity among B. bruxellensis strains. B. bruxellensis is one of the microbial species most resistant to environmental constraints in wine. It is the best adapted to growing in wine and spoiling it by volatile phenol production. However, different B. bruxellensis strains exhibit varying characteristics, particularly their capacity to produce volatile phenols. This implies that certain strains are more prejudicial than others. Further studies are required to determine the molecular causes of this intraspecific diversity.Keywords: Brettanomyces bruxellensis, strain diversity, physiology, volatile phenols

Complex mineralization at large ore deposits in the Russian Far East

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Schneider, A. A.; Malyshev, Yu. F.; Goroshko, M. V.; Romanovsky, N. P.

2011-04-01

Genetic and mineralogical features of large deposits with complex Sn, W, and Mo mineralization in the Sikhote-Alin and Amur-Khingan metallogenic provinces are considered, as well as those of raremetal, rare earth, and uranium deposits in the Aldan-Stanovoi province. The spatiotemporal, geological, and mineralogical attributes of large deposits are set forth, and their geodynamic settings are determined. These attributes are exemplified in the large Tigriny Sn-W greisen-type deposit. The variation of regional tectonic settings and their spatial superposition are the main factor controlling formation of large deposits. Such a variation gives rise to multiple reactivation of the ore-magmatic system and long-term, multistage formation of deposits. Pulsatory mineralogical zoning with telescoped mineral assemblages related to different stages results in the formation of complex ores. The highest-grade zones of mass discharge of hydrothermal solutions are formed at the deposits. The promising greisen-type mineralization with complex Sn-W-Mo ore is suggested to be an additional source of tungsten and molybdenum. The Tigriny, Pravourminsky, and Arsen'evsky deposits, as well as deposits of the Komsomol'sk and Khingan-Olonoi ore districts are examples. Large and superlarge U, Ta, Nb, Be, and REE deposits are localized in the southeastern Aldan-Stanovoi Shield. The Ulkan and Arbarastakh ore districts attract special attention. The confirmed prospects of new large deposits with Sn, W, Mo, Ta, Nb, Be, REE, and U mineralization in the south of the Russian Far East assure expediency of further geological exploration in this territory.

Investigating mechanically induced phase response of the tissue by using high-speed phase-resolved optical coherence tomography (Conference Presentation)

Science.gov (United States)

Ling, Yuye; Hendon, Christine P.

2017-02-01

Phase-resolved optical coherence tomography (OCT), a functional extension of OCT, provides depth-resolved phase information with extra contrast. In cardiology, changes in the mechanical properties have been associated with tissue remodeling and disease progression. Here we present the capability of profiling structural deformation of the sample in vivo by using a highly stable swept source OCT system The system, operating at 1300 nm, has an A-line acquisition rate of 200 kHz. We measured the phase noise floor to be 6.5 pm±3.2 pm by placing a cover slip in the sample arm, while blocking the reference arm. We then conducted a vibrational frequency test by measuring the phase response from a polymer membrane stimulated by a pure tone acoustic wave from 10 kHz to 80 kHz. The measured frequency response agreed with the known stimulation frequency with an error < 0.005%. We further measured the phase response of 7 fresh swine hearts obtained from Green Village Packing Company through a mechanical stretching test, within 24 hours of sacrifice. The heart tissue was cut into a 1 mm slices and fixed on two motorized stages. We acquired 100,000 consecutive M-scans, while the sample is stretched at a constant velocity of 10 um/s. The depth-resolved phase image presents linear phase response over time at each depth, but the slope varies among tissue types. Our future work includes refining our experiment protocol to quantitatively measured the elastic modulus of the tissue in vivo and building a tissue classifier based on depth-resolved phase information.

Study of the controllable reactivity of aluminum alloys and their promising application for hydrogen generation

International Nuclear Information System (INIS)

Fan Meiqiang; Sun Lixian; Xu Fen

2010-01-01

The hydrolysis performances of two aluminum alloys are investigated as their reactivity can be controlled via the different additives. The additive of NaCl has the positive effect to improve the hydrolysis properties of the aluminum alloys with quicker hydrolysis kinetic and lower hydrolysis temperature. For examples, in 6 min of hydrolysis reaction, the Al-5 wt%Hg-5 wt%NaCl can produce 971 mL g -1 hydrogen, higher than 917 mL g -1 hydrogen from Al-10 wt%Hg alloy. The Al-In-NaCl alloy has lower hydrolysis temperature about 10 K than that of Al-In alloy. Meanwhile, the reactivity of Al alloys can be improved or reduced via the additive metals. It can be found that the additive cadmium can reduce the reactivity of Al-Hg alloy. The Al-Hg-Cd alloys can keep good stability at the moist atmosphere below 343 K and have excellent hydrolysis performance around 343-373 K. The debased reactivity of Al-Hg-Cd composite comes from the formation of CdHg 2 compounds in the milling process. But the additive Zn and Ga doped into the Al-In-NaCl alloys can quickly increase the reactivity of the alloy which can quickly react with water at room temperature and have high hydrogen yield up to the theoretic value. Therefore, it is a promising possibility that the controllable reactivity of aluminum alloys can be obtained through the different additive according to the practical request, and the Al alloys can produce pure hydrogen for the fuel cell via the hydrolysis reaction.

The effect of cerebral monitoring on recovery after sevoflurane anesthesia in ambulatory setting in children: A comparison among bispectral index, A-line autoregressive index, and standard practice

Directory of Open Access Journals (Sweden)

Wen-Wei Liao

2011-01-01

Conclusion: BIS- and AAI- guided titration sevoflurane anesthesia could result in shortened recovery and reduced sevoflurane concentration and consumption without affecting the quality of recovery in children receiving ambulatory urologic surgery. The beneficial effects of AAI- and BIS-guided anesthesia in pediatric ambulatory surgeries are similar.

Mesenteric cryptococcal granuloma in a dog caused by Cryptococcus neoformans var. grubii

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Rodrigues-Hoffmann A

2012-09-01

Full Text Available Jennifer R Cook, Karen E Russell, Kristin B Eden, Aline Rodrigues-HoffmannDepartment of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USAAbstract: Although cryptococcosis is usually associated with respiratory and neurologic signs in domestic species (such as sneeze, cough, nasal discharge, seizures, ataxia, clinical manifestations of the disease may be more subtle and nonspecific. A 3-year-old male castrated Boxer dog presented with a history of chronic vomiting, diarrhea, weight loss, and lethargy. At no time had respiratory or neurologic signs been noted by the owners or the primary care veterinarian. Palpation of an abdominal mass revealed an atypical lesion location: a large (16 × 9 × 7 cm mass at the root of the mesentery. Diagnosis was achieved through cytology of this mass and a positive serologic Cryptococcus capsular antigen titer; polymerase chain reaction was utilized for speciation of the abdominal isolate as Cryptococcus neoformans variety grubii. The animal was euthanized due to poor prognosis. After necropsy and histopathologic analysis, the mesenteric mass and associated lymph nodes were identified as large fungal granulomas. This is a rare manifestation of cryptococcosis, involving several visceral organs, with no remaining evidence of the route of entry of the organism. As prompt diagnosis of mycotic illness is paramount to successful management, this case indicates that cryptococcal infection should be considered as a differential diagnosis in dogs with gastrointestinal signs and lymphadenopathy. The protean nature of cryptococcosis is discussed within the context of a brief review of emerging and unresolved issues in pathogenesis.Keywords: Cryptococcus gattii, granuloma, lymphadenitis

Electron-beam and combined e-b and microwave processing of dried food ingredients

International Nuclear Information System (INIS)

Ferdes, O.; Minea, R.; Martin, D.; Tirlea, A.; Badea, M.; Oproiu, C.

1998-01-01

Complete text of publication follows. There are summarized and presented the results on the irradiated dried food ingredients, as starches, flour, spices, enzymes, pigments. It has investigated the electron-beam and microwave processing to achieve the hygienic and microbiological quality requirements for these materials. There are presented the results regarding the e-b and microwave effects on the main specific parameters (nutritional; microbiological; physical and chemical) for each item. Irradiation has carried out to different electron accelerators, mainly to ALIN-7 linac (W e ∼6 MeV) and using a special designed microwave equipment (2.45 GHz magnetron of 850 W maximum output power). The samples have been irradiated up to 25 kGy (dose rate ∼ 2.0 kGy/min) and there were treated by microwaves (250 W-550 W) for different exposure time. There have analyzed and presented the influence of these two physical fields on some common physical, biochemical and microbiological properties (mainly the total germ count, CFU/g) of these food materials. The main technological and physical characteristics of the materials are preserved, under irradiation up to 10 kGy and microwave treatment in the case of satisfying the national requirements for food and food grade additives microbiological load. The combined treatment seems to be present a synergistic effect arising on non-thermal basis. From these results it could be pointed out that electron-beam and microwave treatment is feasible and represents an alternative to other hygienization techniques for the dried food ingredients. It should be considered that combined treatments lead to reducing irradiation dose without losing the microbicidal effects

Canine distemper virus as a threat to wild tigers in Russia and across their range.

Science.gov (United States)

Gilbert, Martin; Soutyrina, Svetlana V; Seryodkin, Ivan V; Sulikhan, Nadezhda; Uphyrkina, Olga V; Goncharuk, Mikhail; Matthews, Louise; Cleaveland, Sarah; Miquelle, Dale G

2015-07-01

Canine distemper virus (CDV) has recently been identified in populations of wild tigers in Russia and India. Tiger populations are generally too small to maintain CDV for long periods, but are at risk of infections arising from more abundant susceptible hosts that constitute a reservoir of infection. Because CDV is an additive mortality factor, it could represent a significant threat to small, isolated tiger populations. In Russia, CDV was associated with the deaths of tigers in 2004 and 2010, and was coincident with a localized decline of tigers in Sikhote-Alin Biosphere Zapovednik (from 25 tigers in 2008 to 9 in 2012). Habitat continuity with surrounding areas likely played an important role in promoting an ongoing recovery. We recommend steps be taken to assess the presence and the impact of CDV in all tiger range states, but should not detract focus away from the primary threats to tigers, which include habitat loss and fragmentation, poaching and retaliatory killing. Research priorities include: (i) recognition and diagnosis of clinical cases of CDV in tigers when they occur; and (ii) collection of baseline data on the health of wild tigers. CDV infection of individual tigers need not imply a conservation threat, and modeling should complement disease surveillance and targeted research to assess the potential impact to tiger populations across the range of ecosystems, population densities and climate extremes occupied by tigers. Describing the role of domestic and wild carnivores as contributors to a local CDV reservoir is an important precursor to considering control measures. © 2015 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and Wiley Publishing Asia Pty Ltd.

Estimating the potential impact of canine distemper virus on the Amur tiger population (Panthera tigris altaica) in Russia.

Science.gov (United States)

Gilbert, Martin; Miquelle, Dale G; Goodrich, John M; Reeve, Richard; Cleaveland, Sarah; Matthews, Louise; Joly, Damien O

2014-01-01

Lethal infections with canine distemper virus (CDV) have recently been diagnosed in Amur tigers (Panthera tigris altaica), but long-term implications for the population are unknown. This study evaluates the potential impact of CDV on a key tiger population in Sikhote-Alin Biosphere Zapovednik (SABZ), and assesses how CDV might influence the extinction potential of other tiger populations of varying sizes. An individual-based stochastic, SIRD (susceptible-infected-recovered/dead) model was used to simulate infection through predation of infected domestic dogs, and/or wild carnivores, and direct tiger-to-tiger transmission. CDV prevalence and effective contact based on published and observed data was used to define plausible low- and high-risk infection scenarios. CDV infection increased the 50-year extinction probability of tigers in SABZ by 6.3% to 55.8% compared to a control population, depending on risk scenario. The most significant factors influencing model outcome were virus prevalence in the reservoir population(s) and its effective contact rate with tigers. Adjustment of the mortality rate had a proportional impact, while inclusion of epizootic infection waves had negligible additional impact. Small populations were found to be disproportionately vulnerable to extinction through CDV infection. The 50-year extinction risk in populations consisting of 25 individuals was 1.65 times greater when CDV was present than that of control populations. The effects of density dependence do not protect an endangered population from the impacts of a multi-host pathogen, such as CDV, where they coexist with an abundant reservoir presenting a persistent threat. Awareness of CDV is a critical component of a successful tiger conservation management policy.

Estimating the potential impact of canine distemper virus on the Amur tiger population (Panthera tigris altaica in Russia.

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Martin Gilbert

Full Text Available Lethal infections with canine distemper virus (CDV have recently been diagnosed in Amur tigers (Panthera tigris altaica, but long-term implications for the population are unknown. This study evaluates the potential impact of CDV on a key tiger population in Sikhote-Alin Biosphere Zapovednik (SABZ, and assesses how CDV might influence the extinction potential of other tiger populations of varying sizes. An individual-based stochastic, SIRD (susceptible-infected-recovered/dead model was used to simulate infection through predation of infected domestic dogs, and/or wild carnivores, and direct tiger-to-tiger transmission. CDV prevalence and effective contact based on published and observed data was used to define plausible low- and high-risk infection scenarios. CDV infection increased the 50-year extinction probability of tigers in SABZ by 6.3% to 55.8% compared to a control population, depending on risk scenario. The most significant factors influencing model outcome were virus prevalence in the reservoir population(s and its effective contact rate with tigers. Adjustment of the mortality rate had a proportional impact, while inclusion of epizootic infection waves had negligible additional impact. Small populations were found to be disproportionately vulnerable to extinction through CDV infection. The 50-year extinction risk in populations consisting of 25 individuals was 1.65 times greater when CDV was present than that of control populations. The effects of density dependence do not protect an endangered population from the impacts of a multi-host pathogen, such as CDV, where they coexist with an abundant reservoir presenting a persistent threat. Awareness of CDV is a critical component of a successful tiger conservation management policy.

Estimating the Potential Impact of Canine Distemper Virus on the Amur Tiger Population (Panthera tigris altaica) in Russia

Science.gov (United States)

Gilbert, Martin; Miquelle, Dale G.; Goodrich, John M.; Reeve, Richard; Cleaveland, Sarah; Matthews, Louise; Joly, Damien O.

2014-01-01

Lethal infections with canine distemper virus (CDV) have recently been diagnosed in Amur tigers (Panthera tigris altaica), but long-term implications for the population are unknown. This study evaluates the potential impact of CDV on a key tiger population in Sikhote-Alin Biosphere Zapovednik (SABZ), and assesses how CDV might influence the extinction potential of other tiger populations of varying sizes. An individual-based stochastic, SIRD (susceptible-infected-recovered/dead) model was used to simulate infection through predation of infected domestic dogs, and/or wild carnivores, and direct tiger-to-tiger transmission. CDV prevalence and effective contact based on published and observed data was used to define plausible low- and high-risk infection scenarios. CDV infection increased the 50-year extinction probability of tigers in SABZ by 6.3% to 55.8% compared to a control population, depending on risk scenario. The most significant factors influencing model outcome were virus prevalence in the reservoir population(s) and its effective contact rate with tigers. Adjustment of the mortality rate had a proportional impact, while inclusion of epizootic infection waves had negligible additional impact. Small populations were found to be disproportionately vulnerable to extinction through CDV infection. The 50-year extinction risk in populations consisting of 25 individuals was 1.65 times greater when CDV was present than that of control populations. The effects of density dependence do not protect an endangered population from the impacts of a multi-host pathogen, such as CDV, where they coexist with an abundant reservoir presenting a persistent threat. Awareness of CDV is a critical component of a successful tiger conservation management policy. PMID:25354196

Rare metal granites in the structures of the Russian sector of Pacific ore belt

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В. И. Алексеев

2016-08-01

Full Text Available Data are presented on the geology of areas of rare metal granites proliferation in the Russian sector of the Pacific Ore Belt that make one take a fresh look at the East Asian granitoid area to update its metallogeny. History is reviewed of studying rare metal granites of the Russian Far East. As a rule, these are found in the vicinity of major tungsten-stanniferous ore deposits, except much later than discovering the former, at the stages of their assessment and survey. Rare earth granites are usually missed by the geologists during the early stages of regional geological surveys due to their small size, weak eroding and external similarity with earlier granites. Using the examples of the Central Polousny, Badzhal and Kuyviveem-Pyrekakay regions the structural and geological conditions are characterized of localization of rare metal granites. Comparative analysis of geological situations made it possible to formulate the areal character of manifestation of rare metal granites; their confinedness to late Mesozoic orogenic arched uplifts of bogen structures above deep granitoid batholiths; positioning in the areas where longitudinal and transversal deep laying faults cross; gravitation to the environs of pre-Cambrian median masses. Similarity of structural-geological conditions for manifestation of the well-studied ore-containing granites serves to confirm the hypothesis on the joint stage of late Cretaceous rare metal magmatism in the Russian sector of the Pacific Ore Belt and the existence in the region of a magmatic super-province – the Far East belt of rare metal granites that includes the Novosibirsk-Chukotka, the Yana-Kolyma and the Sikhote-Alin rare metal – granite provinces.

An electron beam irradiation method for modification of surface electrical resistivity of polyamides

International Nuclear Information System (INIS)

Brasoveanu, M. M.; Timus, D.; Nemtanu, M. R.

2002-01-01

The synthetic textiles which have mechanical and processing properties and a low price are very useful and consequently in high demand. The low antistatic qualities are an important disadvantage, but not impossible to eliminate. The aim of paper is the study of modification the antistatic properties of polyamide by grafting of monomers by irradiation. Twisted and unthermofixed polyamide-6 fibre from CFS Savinesti were investigated. The samples of polyamide were irradiated with an electron beam from the ALIN-7 linear accelerator of Electron Accelerators Laboratory of National Institute for Lasers, Plasma and Radiation Physics, Bucharest. Immediately after irradiation, the samples were measured by electron spin resonance (ESR). ESR spectra were recorded at room temperature using a Jeol spectrometer, JES-ME-3X, with 100 kHz modulation. In polyamide-6 at least two irradiation defect types occurred which present EPR signal by electron beam irradiation. Unstable centres of type A presenting an incompletely resolved hyperfine structure can be attributed to radicals -N-CH 2 - or -NH-CH-CH 2 -. Both radicals can present at room temperature a five-line spectrum like the radical formed in this work. First radical appears with very low probability and if the free bond is at one of carbon atoms then it will be stabilized immediately in a position from nitrogen. These type A radicals can appear in same zone and then they can react and form unsaturated bonds or bridge between the polymeric chains. Thus, it will appear the type B defects which were more stabile and without structure. On these double chains one can graft vinylic monomers even after time intervals longer from irradiation. (authors)

Cat amniotic membrane multipotent cells are nontumorigenic and are safe for use in cell transplantation

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Vidane AS

2014-08-01

Full Text Available Atanasio S Vidane,1 Aline F Souza,1 Rafael V Sampaio,1 Fabiana F Bressan,2 Naira C Pieri,1 Daniele S Martins,2 Flavio V Meirelles,2 Maria A Miglino,1 Carlos E Ambrósio2 1Department of Surgery, Faculty of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, Brazil; 2Department of Veterinary Medicine, Faculty of Animal Sciences and Food Engineering, University of São Paulo, São Paulo, Brazil Abstract: Amnion-derived mesenchymal stem cells (AMSCs are multipotent cells with an enhanced ability to differentiate into multiple lineages. AMSCs can be acquired through noninvasive methods, and therefore are exempt from the typical ethical issues surrounding stem cell use. The objective of this study was to isolate and characterize AMSCs from a cat amniotic membrane for future application in regenerative medicine. The cat AMSCs were harvested after mechanical and enzymatic digestion of amnion. In culture medium, the cat AMSCs adhered to a plastic culture dish and displayed a fibroblast-like morphology. Immunophenotyping assays were positive for the mesenchymal stem cell-specific markers CD73 and CD90 but not the hematopoietic markers CD34, CD45, and CD79. Under appropriate conditions, the cat AMSCs differentiated into osteogenic, chondrogenic, and adipogenic cell lineages. One advantage of cat AMSCs was nonteratogenicity, assessed 4 weeks post injection of undifferentiated AMSCs into immunodeficient mice. These findings suggest that cat amniotic membranes may be an important and useful source of mesenchymal stem cells for clinical applications, especially for cell or tissue replacement in chronic and degenerative diseases. Keywords: amnion, cats, cell differentiation, fetal membranes, mesenchymal cells

Benefits of short inspiratory muscle training on exercise capacity, dyspnea, and inspiratory fraction in COPD patients

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Barakat Shahin

2008-10-01

Full Text Available Barakat Shahin1, Michele Germain2, Alzahouri Kazem3, Guy Annat41Department of Physiology, University of Claude Bernard Lyon I, Lyon, France; 2Chef of the Service of EFR, Hospital of the Croix-Rousse at Lyon, France; 3Department of Medical Informatics, Hospital of St. Julien, Nancy, France; 4Department of Physiology, UFR Médecine Lyon Grange-Blanche Université Claude Bernard Lyon I, INSERM ESPRI ERI 22, Lyon, FranceAbstract: Static lung hyperinflation has important clinical consequences in patients with chronic obstructive pulmonary disease (COPD. Given that most of these patients have respiratory and peripheral muscle weakness, dyspnea and functional exercise capacity may improve as a result of inspiratory muscle training (IMT. The present study is designed to investigate the benefits of a short outpatient program of IMT on inspiratory muscle performance, exercise capacity, perception of dyspnea, and the inspiratory fraction (IF. Thirty patients (24 males, 6 females with significant COPD (forced expiratory volume in one second [FEV1] = 46.21% ± 6.7% predicted, FEV1 = 33.6% ± 8.04% predicted were recruited for this study and had 3 months of IMT (30 minutes/day for 6 days/week in an outpatient clinic. Following IMT, there was a statistically significant increase in inspiratory muscle performance (an increase of the maximal inspiratory pressure from 59% ± 19.1% to 79% ± 21.85% predicted; p = 0.0342, a decrease in dyspnea (from 5.8 ± 0.78 to 1.9 ± 0.57; p = 0.0001, an increase in the distance walked during the 6 minute walk test, from 245 ± 52.37 m to 302 ± 41.30 m, and finally an increase in the IF (the new prognostic factor in COPD from 27.6 ± 9.7% to 31.4% ± 9.8%. The present study concludes that in patients with significant COPD, IMT results in improvement in performance, exercise capacity, sensation of dyspnea, and moreover an improvement in the IF prognostic factor.Keywords: inspiratory muscle training, dyspnea, inspiratory

Arterial pulse wave velocity, inflammatory markers, pathological GH and IGF states, cardiovascular and cerebrovascular disease

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Michael R Graham

2008-12-01

Full Text Available Michael R Graham1, Peter Evans2, Bruce Davies1, Julien S Baker11Health and Exercise Science Research Unit, Faculty of Health Sport and Science, University of Glamorgan, Pontypridd, Wales, United Kingdom; 2Royal Gwent Hospital, Newport, Gwent, United KingdomAbstract: Blood pressure (BP measurements provide information regarding risk factors associated with cardiovascular disease, but only in a specific artery. Arterial stiffness (AS can be determined by measurement of arterial pulse wave velocity (APWV. Separate from any role as a surrogate marker, AS is an important determinant of pulse pressure, left ventricular function and coronary artery perfusion pressure. Proximal elastic arteries and peripheral muscular arteries respond differently to aging and to medication. Endogenous human growth hormone (hGH, secreted by the anterior pituitary, peaks during early adulthood, declining at 14% per decade. Levels of insulin-like growth factor-I (IGF-I are at their peak during late adolescence and decline throughout adulthood, mirror imaging GH. Arterial endothelial dysfunction, an accepted cause of increased APWV in GH deficiency (GHD is reversed by recombinant human (rh GH therapy, favorably influencing the risk for atherogenesis. APWV is a noninvasive method for measuring atherosclerotic and hypertensive vascular changes increases with age and atherosclerosis leading to increased systolic blood pressure and increased left ventricular hypertrophy. Aerobic exercise training increases arterial compliance and reduces systolic blood pressure. Whole body arterial compliance is lowered in strength-trained individuals. Homocysteine and C-reactive protein are two infl ammatory markers directly linked with arterial endothelial dysfunction. Reviews of GH in the somatopause have not been favorable and side effects of treatment have marred its use except in classical GHD. Is it possible that we should be assessing the combined effects of therapy with rhGH and rh

Assessment study of the nutritional status, eating habits and physical activity of the schooled population of Centelles, Hostalets de Balenyà and Sant Martí de Centelles (ALIN 2014 Study).

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Aguilà, Queralt; Ramón, Maria Àngels; Matesanz, Susana; Vilatimó, Ramon; Del Moral, Irene; Brotons, Carles; Ulied, Àngels

2017-03-01

Malnourishment can be caused by either a lack of food or an excess of low-nutrient foods. Due to several factors, this predisposes children to academic failure. The objective of this study is to estimate the prevalence of school children with eating problems, study their nutrition level, food quality in the diet, and level of physical activity. The study involved the school children between 3 months and 16.5 years of age in the municipalities of Centelles, Hostalets de Balenyà and Sant Martí de Centelles. Personal, age, nutrition and physical activity data were collected for the descriptive and bivariate analyses. A total of 1,374 children were included, of which 122 were under 3 years of age (8.9%). Obesity was recorded in 2.5%, while 17.2, 15.6 and 64.8% were overweight, underweight and of normal weight, respectively. The remaining 1,252 children were over 3 years of age (91.1%), and obesity was recorded in 8.1%, while 26.1, 11.0 and 62.9% were overweight, underweight and of normal weight, respectively. Adherence to the Mediterranean diet decreased significantly with increasing age. The maintenance of body weight was significantly correlated to the consumption of carbohydrates for breakfast before going to school, daily fruit consumption, and not having a need for care from the social services. The differences in physical activity and a sedentary lifestyle proved significant between males and females. Being underweight and overweight are factors related to eating habits and dependency upon the social services. Copyright © 2017 SEEN. Publicado por Elsevier España, S.L.U. All rights reserved.

Fireball data analysis: bridging the gap between small solar system bodies and meteorite studies

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Gritsevich, Maria; Moreno-Ibáñez, Manuel; Kuznetsova, Daria; Bouquet, Alexis; Trigo-Rodríguez, Josep; Peltoniemi, Jouni; Koschny, Detlef

2015-08-01

One of the important steps in identification of meteorite-producing fireballs and prediction of impact threat to Earth raised by potentially hazardous asteroids is the understanding and modeling of processes accompanying the object’s entry into the terrestrial atmosphere (Gritsevich et al., 2012). Such knowledge enables characterization, simulation and classification of possible impact consequences with further reommendation for potential meteorite searches. Using dimensionless expressions, which involve the pre-atmospheric meteoroid parameters, we have built physically based parametrisation to describe changes in mass, height, velocity and luminosity of the object along its atmospheric path (Gritsevich and Koschny, 2011; Bouquet et al., 2014). The developed model is suitable to estimate a number of crucial unknown values including shape change coefficient, ablation rate, and surviving meteorite mass. It is also applicable to predict the terminal height of the luminous flight and therefore, duration of the fireball (Moreno-Ibáñez et al., 2015). Besides the model description, we demonstrate its application using the wide range of observational data from meteorite-producing fireballs appearing annually (such as Košice) to larger scale impacts (such as Chelyabinsk, Sikhote-Alin and Tunguska).REFERENCESBouquet A., Baratoux D., Vaubaillon J., Gritsevich M.I., Mimoun D., Mousis O., Bouley S. (2014): Planetary and Space Science, 103, 238-249, http://dx.doi.org/10.1016/j.pss.2014.09.001Gritsevich M., Koschny D. (2011): Icarus, 212(2), 877-884, http://dx.doi.org/10.1016/j.icarus.2011.01.033Gritsevich M.I., Stulov V.P., Turchak L.I. (2012): Cosmic Research, 50(1), 56-64, http://dx.doi.org/10.1134/S0010952512010017Moreno-Ibáñez M., Gritsevich M., Trigo-Rodríguez J.M. (2015): Icarus, 250, 544-552, http://dx.doi.org/10.1016/j.icarus.2014.12.027

Fungal diseases: could nanostructured drug delivery systems be a novel paradigm for therapy?

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Voltan AR

2016-08-01

Full Text Available Aline Raquel Voltan,1 Guillermo Quindós,2 Kaila P Medina Alarcón,3 Ana Marisa Fusco-Almeida,3 Maria José Soares Mendes-Giannini,3 Marlus Chorilli1 1Department of Drugs and Medicines, Faculty of Pharmaceutical Sciences, Univ. Estadual Paulista, Araraquara, Sao Paulo, Brazil; 2Immunology, Microbiology, and Parasitology Department, Facultad de Medicina y Odontología, Universidad del País Vasco, Bilbao, Spain; 3Department of Clinical Analysis, Faculdade de Ciências Farmacêuticas, Univ. Estadual Paulista, Araraquara, Sao Paulo, Brazil Abstract: Invasive mycoses are a major problem for immunocompromised individuals and patients in intensive care units. Morbidity and mortality rates of these infections are high because of late diagnosis and delayed treatment. Moreover, the number of available antifungal agents is low, and there are problems with toxicity and resistance. Alternatives for treating invasive fungal infections are necessary. Nanostructured systems could be excellent carriers for antifungal drugs, reducing toxicity and targeting their action. The use of nanostructured systems for antifungal therapy began in the 1990s, with the appearance of lipid formulations of amphotericin B. This review encompasses different antifungal drug delivery systems, such as liposomes, carriers based on solid lipids and nanostructure lipids, polymeric nanoparticles, dendrimers, and others. All these delivery systems have advantages and disadvantages. Main advantages are the improvement in the antifungal properties, such as bioavailability, reduction in toxicity, and target tissue, which facilitates innovative therapeutic techniques. Conversely, a major disadvantage is the high cost of production. In the near future, the use of nanosystems for drug delivery strategies can be used for delivering peptides, including mucoadhesive systems for the treatment of oral and vaginal candidiasis. Keywords: fungal diseases, antifungal agents, amphotericin B, azoles

Defense of fake fingerprint attacks using a swept source laser optical coherence tomography setup

Science.gov (United States)

Meissner, Sven; Breithaupt, Ralph; Koch, Edmund

2013-03-01

The most established technique for the identification at biometric access control systems is the human fingerprint. While every human fingerprint is unique, fingerprints can be faked very easily by using thin layer fakes. Because commercial fingerprint scanners use only a two-dimensional image acquisition of the finger surface, they can only hardly differentiate between real fingerprints and fingerprint fakes applied on thin layer materials. A Swept Source OCT system with an A-line rate of 20 kHz and a lateral and axial resolution of approximately 13 μm, a centre wavelength of 1320 nm and a band width of 120 nm (FWHM) was used to acquire fingerprints and finger tips with overlying fakes. Three-dimensional volume stacks with dimensions of 4.5 mm x 4 mm x 2 mm were acquired. The layering arrangement of the imaged finger tips and faked finger tips was analyzed and subsequently classified into real and faked fingerprints. Additionally, sweat gland ducts were detected and consulted for the classification. The manual classification between real fingerprints and faked fingerprints results in almost 100 % correctness. The outer as well as the internal fingerprint can be recognized in all real human fingers, whereby this was not possible in the image stacks of the faked fingerprints. Furthermore, in all image stacks of real human fingers the sweat gland ducts were detected. The number of sweat gland ducts differs between the test persons. The typical helix shape of the ducts was observed. In contrast, in images of faked fingerprints we observe abnormal layer arrangements and no sweat gland ducts connecting the papillae of the outer fingerprint and the internal fingerprint. We demonstrated that OCT is a very useful tool to enhance the performance of biometric control systems concerning attacks by thin layer fingerprint fakes.

Fingerprint fake detection by optical coherence tomography

Science.gov (United States)

Meissner, Sven; Breithaupt, Ralph; Koch, Edmund

2013-03-01

The most established technique for the identification at biometric access control systems is the human fingerprint. While every human fingerprint is unique, fingerprints can be faked very easily by using thin layer fakes. Because commercial fingerprint scanners use only a two-dimensional image acquisition of the finger surface, they can only hardly differentiate between real fingerprints and fingerprint fakes applied on thin layer materials. A Swept Source OCT system with an A-line rate of 20 kHz and a lateral and axial resolution of approximately 13 μm, a centre wavelength of 1320 nm and a band width of 120 nm (FWHM) was used to acquire fingerprints and finger tips with overlying fakes. Three-dimensional volume stacks with dimensions of 4.5 mm x 4 mm x 2 mm were acquired. The layering arrangement of the imaged finger tips and faked finger tips was analyzed and subsequently classified into real and faked fingerprints. Additionally, sweat gland ducts were detected and consulted for the classification. The manual classification between real fingerprints and faked fingerprints results in almost 100 % correctness. The outer as well as the internal fingerprint can be recognized in all real human fingers, whereby this was not possible in the image stacks of the faked fingerprints. Furthermore, in all image stacks of real human fingers the sweat gland ducts were detected. The number of sweat gland ducts differs between the test persons. The typical helix shape of the ducts was observed. In contrast, in images of faked fingerprints we observe abnormal layer arrangements and no sweat gland ducts connecting the papillae of the outer fingerprint and the internal fingerprint. We demonstrated that OCT is a very useful tool to enhance the performance of biometric control systems concerning attacks by thin layer fingerprint fakes.

Characterization and Comparative Analysis of Olfactory Receptor Co-Receptor Orco Orthologs Among Five Mirid Bug Species

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Qi Wang

2018-03-01

Full Text Available The phytophagous mirid bugs of Apolygus lucorum, Lygus pratensis as well as three Adelphocoris spp., including Adelphocoris lineolatus, A. suturalis, and A. fasciaticollis are major pests of multiple agricultural crops in China, which have distinct geographical distribution and occurrence ranges. Like many insect species, these bugs heavily rely on olfactory cues to search preferred host plants, thereby investigation on functional co-evolution and divergence of olfactory genes seems to be necessary and is of great interest. In the odorant detection pathway, olfactory receptor co-receptor (Orco plays critical role in the perception of odors. In this study, we identified the full-length cDNA sequences encoding three putative Orcos (AsutOrco, AfasOrco, and LpraOrco in bug species of A. suturalis, A. fasciaticollis, and L. pratensis based on homology cloning method. Next, sequence alignment, membrane topology and gene structure analysis showed that these three Orco orthologs together with previously reported AlinOrco and AlucOrco shared high amino acid identities and similar topology structure, but had different gene structure especially at the length and insertion sites of introns. Furthermore, the evolutional estimation on the ratios of non-synonymous to synonymous (Ka/Ks revealed that Orco genes were under strong purifying selection, but the degrees of variation were significant different between genera. The results of quantitative real-time PCR experiments showed that these five Orco genes had a similar antennae-biased tissue expression pattern. Taking these data together, it is thought that Orco genes in the mirid species could share conserved olfaction roles but had different evolution rates. These findings would lay a foundation to further investigate the molecular mechanisms of evolutionary interactions between mirid bugs and their host plants, which might in turn contribute to the development of pest management strategy for mirid bugs.

Long‐term creep rates on the Hayward Fault: evidence for controls on the size and frequency of large earthquakes

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Lienkaemper, James J.; McFarland, Forrest S.; Simpson, Robert W.; Bilham, Roger; Ponce, David A.; Boatwright, John; Caskey, S. John

2012-01-01

The Hayward fault (HF) in California exhibits large (Mw 6.5–7.1) earthquakes with short recurrence times (161±65 yr), probably kept short by a 26%–78% aseismic release rate (including postseismic). Its interseismic release rate varies locally over time, as we infer from many decades of surface creep data. Earliest estimates of creep rate, primarily from infrequent surveys of offset cultural features, revealed distinct spatial variation in rates along the fault, but no detectable temporal variation. Since the 1989 Mw 6.9 Loma Prieta earthquake (LPE), monitoring on 32 alinement arrays and 5 creepmeters has greatly improved the spatial and temporal resolution of creep rate. We now identify significant temporal variations, mostly associated with local and regional earthquakes. The largest rate change was a 6‐yr cessation of creep along a 5‐km length near the south end of the HF, attributed to a regional stress drop from the LPE, ending in 1996 with a 2‐cm creep event. North of there near Union City starting in 1991, rates apparently increased by 25% above pre‐LPE levels on a 16‐km‐long reach of the fault. Near Oakland in 2007 an Mw 4.2 earthquake initiated a 1–2 cm creep event extending 10–15 km along the fault. Using new better‐constrained long‐term creep rates, we updated earlier estimates of depth to locking along the HF. The locking depths outline a single, ∼50‐km‐long locked or retarded patch with the potential for an Mw∼6.8 event equaling the 1868 HF earthquake. We propose that this inferred patch regulates the size and frequency of large earthquakes on HF.

El proyecto historiográfico del Archetypum Naiarense

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Alberto MONTANER FRUTOS

2009-07-01

Full Text Available La transmission conjointe de la Chronica Naiarensis, de l’Historia Wambae de saint Julien de Tolède, de l’Historia Roderici et de l’Ordo regum Naiarensis est attestée par au moins cinq témoignages (deux directs et trois indirects. Le modèle commun de cette compilation historiographique remonte à un Archetypum Naiarense composé à Santa María la Real de Nájera entre 1190 et 1194. Le projet historiographique implicite dans ce codex en forme de recueil a été celui de présenter une histoire hispanique couvrant l’ensemble du territoire du royaume des Wisigoths, puis des royaumes hispaniques chrétiens, en changeant la perspective néogothique de la tradition historiographique des Asturies et du royaume de León, et en la centrant sur la Castille. En outre, l’Archetypum Naiarense montre une étape intermédiaire entre les compilations encyclopédiques comme la Chronica Albeldense ou le codex de Roda et la compilation de chroniques unitaires telles que celles de Lucas de Tuy et Rodrigo Ximénez de Rada.La transmisión conjunta de la Chronica Naiarensis, la Historia Wambae de San Julián de Toledo, la Historia Roderici y el Ordo regum Naiarensis está atestiguado al menos por cinco testimonios (dos directos y tres indirectos. El modelo común de esta compilación historiográfica remonta a un Archetypum Naiarense compuesto en Santa María la Real de Nájera entre 1190 y 1194. El proyecto historiográfico implícito en este códice repositorio era el trazar una historia hispánica que abarcase todo el territorio del reino visigodo, primero, y de la cristiandad hispánica, después, pero no bajo la perspectiva goticista de la tradición historiográfica asturleonesa, sino desde una más centrada en Castilla. Además, el Archetypum Naiarense establece un estadio intermedio entre los códices misceláneos como el Albeldense o el de Roda y la compilación de crónicas unitarias como la de Lucas de Tuy o Rodrigo Ximénez de Rada.

13th European Workshop on Advanced Control and Diagnosis (ACD 2016)

International Nuclear Information System (INIS)

2017-01-01

13 th European Workshop on Advanced Control and Diagnosis The 13th European Workshop on Advanced Control and Diagnosis (ACD 2016), www.acd2016.eu took place at Hautes Etrudes d’Ingénieur (HEI), Lille, France, on November 17-18, 2016. The annual European Workshop on Advanced Control and Diagnosis has been organized since 2003 by Control Engineering departments of several European universities in Germany, France, the UK, Poland, Italy, Hungary, Denmark and Czech Republic, to bring together senior and junior academics and engineers from diverse fields of automatic control, fault detection, and signal processing. The workshop provides an opportunity for researchers and developers to present their recent theoretical developments, practical applications, or even open problems. It also offers a great opportunity for industrial partners to express their needs and priorities and to review the current activities in the fields. A total of 100 papers have been submitted for ACD 2016. Based on the peer reviews 71 papers were accepted for oral presentation, 4 papers withdrawn, 3 papers not presented. The accepted papers covered areas of Fault Diagnosis, Estimation and Observation, Fault Tolerant Control, Predictive Control, Robust Control, Control Theory, fractional order systems, Modeling and Data °Processing, Software tools and code generation. In addition, four excellent plenary lectures were delivered by experts on their domain: Ir. Serge Legonidec from the company Airbus Safran Launchers, France : An overview of connections between scientific automatic topics and their applications in the propulsive systems, Dr. Ir. Jan-Willem Van Wingerden, Technical University of Delft, Nederland : Wind Energy Control Research, Prof. Sarah Spurgeon, University College London, UK: On discontinuous Observers: From Basic Properties to a Robust Fault Detection and Condition Monitoring Tool, Dr. Joseph-Julien Yame, University of Lorraine, Nancy, France : Data Driven Fault Tolerant Control

Treatment in hospital for alcohol-dependent patients decreases attentional bias

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Flaudias V

2013-05-01

Full Text Available Valentin Flaudias,1,2 Georges Brousse,1,2 Ingrid De Chazeron,1,2 François Planche,2 Julien Brun,2 Pierre-Michel Llorca1,2 1Clermont Université, EA 7280 NPsy-Sydo, Clermont-Ferrand, France; 2Pôle Psychiatrie B, CHU Gabriel-Montpied, Clermont-Ferrand, France Background and objectives: Previous studies in alcohol-dependent patients have shown an attentional bias (AB under related substance cues, which can lead to relapse. This AB can be evaluated by the alcohol Stroop test (AST. The AST is a modified Stroop task in which participants have to name the color of an alcohol-related word or a neutral word. AB is the response-time difference between these two types of words. The goal of the current study was to examine modification of AB during specialized hospitalization for alcohol dependence, with the suppression of a training bias that could be present in within-subject design. Methods: Individuals with alcohol-dependence disorders (Diagnostic and Statistical Manual of Mental Disorders, 4th edition and admitted for withdrawal in the addiction unit of the University Hospital of Clermont-Ferrand (test group, n = 42 and persons with no alcohol or psychiatric disorder (control group, n = 16, recruited among colleagues and friends of the staff, performed the AST. A subgroup of the test group performed the AST in admission (admission group, n = 19, and another subgroup undertook the test immediately before discharge (discharge group, n = 23. Results: Results showed an AB only for patients seen at admission (F[1,55] = 3.283, P = 0.075. Moreover, we observed that the AB in the admission group (mean = 34 ms, standard deviation [SD] = 70.06 was greater than the AB in the control group (mean = 23 ms, SD = 93.42, itself greater than the AB in the discharge group (mean = −12 ms, SD = 93.55 (t[55] = −1.71; P = 0.09. Conclusion: Although the results are preliminary, the present study provides evidence for changes in the AB during alcohol-addiction treatment

IDENTIFICACIÓN DEL AGENTE CAUSAL DE LA ANTRACNOSIS DE Sansevieria spp. EN COSTA RICA

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Gerardo Pérez-León

2013-01-01

Full Text Available Sansevieria spp. (Agavaceae es una ornamental de follaje originaria de África y Asia. S. trifasciata (St es la especie con mayor número de cultivares en el mercado de exportación de Costa Rica a Estados Unidos y Holanda. Muestras foliares de S. trifasciata var. “Hahnii” con lesiones circulares y acuosas (algunas alargadas y secas, fueron analizadas. El patógeno recuperado fue identificado como Colletotrichum sansevieriae Nakamura (CsN mediante pruebas de patogenicidad, morfología y técnicas moleculares. Los aislamientos mono-hifales presentaron coloración crema, crecimiento postrado y escasa producción de conidios. La patogenicidad de CsN se evaluó en 7 variedades de St; Sansevieriasp., var., jiboia; S. cylindrica y las ornamentalesCodiaeum variegatum, Cordelyne terminalis y Dracaena deremensis, mediante 2 sistemas deinoculación: plantas en maceta (invernaderoy hojas separadas (laboratorio; con ambos sereprodujeron los síntomas de la enfermedad. Cinco de las variedades de S. trifasciata desarrollaron síntomas, “Hahnii” la más susceptible. Ninguna de las otras ornamentales presentósíntomas. CsN fue re-aislado de hojas inoculadas (postulados de Koch. La amplificación mediante PCR de la región ITS con los iniciadores ITS5 e ITS4 produjo un fragmento de aproximadamente 600pb, cuya secuencia de nucleótidos fue idéntica para los aislamientos mono-hifales. En el Banco de Genes, la secuencia alineó con accesiones de CsN de Australia y USA, con un índice de simi laridad del 99 al 100%. El análisis filogenético, con base en la región ITS2, agrupó (99% valor debootstrap los aislamientos costarricenses con elaislamiento tipo CsN de Japón y los de Australia y USA. Hasta donde se conoce, éste es el primer informe de la antracnosis de Sansevieria en C. R.

ISVEE 14 Yucatan 2015 14th Symposium of the International Society for Veterinary Epidemiology and Economics.

Science.gov (United States)

de Anda, Jorge Hernández

2017-02-01

(Vitor Goncalves), and (v) animal welfare (Aline Schunemann). This Special Issue includes manuscripts from four of five keynote presentations delivered during ISVEE 14. Copyright © 2016. Published by Elsevier B.V.

MEMS-based handheld fourier domain Doppler optical coherence tomography for intraoperative microvascular anastomosis imaging.

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Yong Huang

Full Text Available To demonstrate the feasibility of a miniature handheld optical coherence tomography (OCT imager for real time intraoperative vascular patency evaluation in the setting of super-microsurgical vessel anastomosis.A novel handheld imager Fourier domain Doppler optical coherence tomography based on a 1.3-µm central wavelength swept source for extravascular imaging was developed. The imager was minimized through the adoption of a 2.4-mm diameter microelectromechanical systems (MEMS scanning mirror, additionally a 12.7-mm diameter lens system was designed and combined with the MEMS mirror to achieve a small form factor that optimize functionality as a handheld extravascular OCT imager. To evaluate in-vivo applicability, super-microsurgical vessel anastomosis was performed in a mouse femoral vessel cut and repair model employing conventional interrupted suture technique as well as a novel non-suture cuff technique. Vascular anastomosis patency after clinically successful repair was evaluated using the novel handheld OCT imager.With an adjustable lateral image field of view up to 1.5 mm by 1.5 mm, high-resolution simultaneous structural and flow imaging of the blood vessels were successfully acquired for BALB/C mouse after orthotopic hind limb transplantation using a non-suture cuff technique and BALB/C mouse after femoral artery anastomosis using a suture technique. We experimentally quantify the axial and lateral resolution of the OCT to be 12.6 µm in air and 17.5 µm respectively. The OCT has a sensitivity of 84 dB and sensitivity roll-off of 5.7 dB/mm over an imaging range of 5 mm. Imaging with a frame rate of 36 Hz for an image size of 1000(lateral×512(axial pixels using a 50,000 A-lines per second swept source was achieved. Quantitative vessel lumen patency, lumen narrowing and thrombosis analysis were performed based on acquired structure and Doppler images.A miniature handheld OCT imager that can be used for intraoperative evaluation of

Anal high-risk human papillomavirus infection and high-grade anal intraepithelial neoplasia detected in women and heterosexual men infected with human immunodeficiency virus

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Gandra S

2015-01-01

Full Text Available Sumanth Gandra, Aline Azar, Mireya WessolosskyDivision of Infectious Disease and Immunology, University of Massachusetts Medical School, Worcester, MA, USABackground: Although anal high-risk human papillomavirus (HR-HPV infection and anal cytological abnormalities are highly prevalent among human immunodeficiency virus (HIV-infected men who have sex with men (MSM, there are insufficient data on these abnormalities among HIV-infected heterosexual men (HSM and women. In this study, we evaluated the prevalence of anal HR-HPV, cytological abnormalities, and performance of these screening tests in detecting high-grade anal intraepithelial neoplasia (AIN2+ among our cohort of HIV-infected MSM and non-MSM (HSM and women.Methods: A single-center, retrospective cohort study was conducted with HIV-infected individuals who underwent anal cancer screening with anal cytology and HR-HPV testing from January 2011 to January 31, 2013.Results: Screening of 221 HIV-infected individuals for both HR-HPV and anal cytology showed the presence of HR-HPV in 54% (abnormal anal cytology 48% of MSM, 28% (abnormal anal cytology 28% of HSM, and 27% (abnormal anal cytology 34% of women. Among 117 (53% individuals with abnormal results (HR-HPV-positive and/or cytology was atypical squamous cells of undetermined significance or above, 67 underwent high resolution anoscopy. Of these 67 individuals, 22 individuals had AIN2+ (17 MSM, four women, and one HSM. HR-HPV correlated better with AIN2+ than with anal cytology on biopsy in both MSM (r=0.29 versus r=0.10; P=0.05 versus P=0.49 and non-MSM (r=0.36 versus r=-0.34; P=0.08 versus P=0.09.Conclusion: Given the presence of AIN2+ in screened HIV-infected HSM and women, routine anal cancer screening in all HIV-infected individuals should be considered. HR-HPV merits further evaluation for anal cancer screening among non-MSM.Keywords: human immunodeficiency virus, anal human papillomavirus, heterosexual men, women, anal cancer

Modelling of plasma-antenna coupling and non-linear radio frequency wave-plasma-wall interactions in the magnetized plasma device under ion cyclotron range of frequencies

International Nuclear Information System (INIS)

Lu, LingFeng

2016-01-01

Ion Cyclotron Resonant Heating (ICRH) by waves in 30-80 MHz range is currently used in magnetic fusion plasmas. Excited by phased arrays of current straps at the plasma periphery, these waves exist under two polarizations. The Fast Wave tunnels through the tenuous plasma edge and propagates to its center where it is absorbed. The parasitically emitted Slow Wave only exists close to the launchers. How much power can be coupled to the center with 1 A current on the straps? How do the emitted radiofrequency (RF) near and far fields interact parasitically with the edge plasma via RF sheath rectification at plasma-wall interfaces? To address these two issues simultaneously, in realistic geometry over the size of ICRH antennas, this thesis upgraded and tested the Self-consistent Sheaths and Waves for ICH (SSWICH) code. SSWICH couples self-consistently RF wave propagation and Direct Current (DC) plasma biasing via non-linear RF and DC sheath boundary conditions (SBCs) at plasma/wall interfaces. Its upgrade is full wave and was implemented in two dimensions (toroidal/radial). New SBCs coupling the two polarizations were derived and implemented along shaped walls tilted with respect to the confinement magnetic field. Using this new tool in the absence of SBCs, we studied the impact of a density decaying continuously inside the antenna box and across the Lower Hybrid (LH) resonance. Up to the memory limits of our workstation, the RF fields below the LH resonance changed with the grid size. However the coupled power spectrum hardly evolved and was only weakly affected by the density inside the box. In presence of SBCs, SSWICH-FW simulations have identified the role of the fast wave on RF sheath excitation and reproduced some key experimental observations. SSWICH-FW was finally adapted to conduct the first electromagnetic and RF-sheath 2D simulations of the cylindrical magnetized plasma device ALINE. (author) [fr

Antibiotic-modifying activity of riachin, a non-cyanogenic cyanoglycoside extracted from Bauhinia pentandra

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Farias PAM

2015-06-01

Full Text Available Pablo Antonio Maia de Farias,1,3 Fernando Gomes Figueredo,2,3 Aline Maria Brito Lucas,3 Rafael Barbosa de Moura,3 Henrique Douglas Melo Coutinho,2 Tania Maria Sarmento da Silva,4 Ana Luiza de Aguiar Rocha Martin,2,3 Marta Maria de França Fonteles1 1Development and Technological Innovation in Medicines, Universidade Federal do Ceará – UFC, Fortaleza-CE, 2College of Biomedicine, Faculdade Leão Sampaio-FLS, 3College of Pharmacy, Faculdade de Medicina Estácio de Juazeiro do Norte-Estácio, Juazeiro do Norte-CE, 4Department of Molecular Sciences, Universidade Federal Rural de Pernambuco, Recife, PE, Brazil Background: The search for new active compounds from the Brazilian flora has intensified in recent years, especially for new drugs with antibiotic potential. Accordingly, the aim of this study was to determine whether riachin has antibiotic activity in itself or is able to modulate the activity of conventional antibiotics.Methods: A non-cyanogenic cyanoglycoside known as riachin was isolated from Bauhinia pentandra, and was tested alone and in combination with three antibiotics (clindamycin, amikacin, and gentamicin against multiresistant bacterial strains (Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus.Results: Riachin did not show significant antibiotic activity when tested alone against any strain (P>0.05. However, when combined with conventional antibiotics, it showed drug-modifying activity against strains of S. aureus exposed to clindamycin (P<0.001 as well as against P. aeruginosa exposed to amikacin (P<0.001. Although riachin did not show direct antibiotic activity, it had synergistic activity when combined with amikacin or clindamycin. The mechanism of action of this synergism is under investigation.Conclusion: The results of this work demonstrate that some substances of natural origin can enhance the effectiveness of certain antibiotics, which means a substantial reduction in the drug dose required and

Design, characterization, and biological evaluation of curcumin-loaded surfactant-based systems for topical drug delivery

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Fonseca-Santos B

2016-09-01

Full Text Available Bruno Fonseca-Santos, Aline Martins dos Santos, Camila Fernanda Rodero, Maria Palmira Daflon Gremião, Marlus Chorilli School of Pharmaceutical Sciences, UNESP – São Paulo State University, Araraquara, São Paulo Brazil Abstract: From previous studies, it has been found that curcumin exhibits an anti-inflammatory activity and is being used for the treatment of skin disorders; however, it is hydrophobic and has weak penetrating ability, resulting in poor drug transport through the stratum corneum. The aim of this study was to develop liquid crystalline systems for topical administration of curcumin for the treatment of inflammation. These liquid crystalline systems were developed from oleic acid, polyoxypropylene (5 polyoxyethylene (20 cetyl alcohol, and water as the surfactant, oil phase, and aqueous phase, respectively. These systems were characterized, and polarized light microscopy showed anisotropy with lamellar mesophases (Formulation 1 and hexagonal mesophases (Formulations 2 and 3, which were confirmed by the peak ratio measured using small-angle X-ray scattering. In addition, rheological tests revealed that the formulations exhibited gel-like behavior (G'>G'', as evidenced by the increased G' values that indicate structured systems. Texture profile analysis showed that hexagonal mesophases have high values of hardness, adhesiveness, and compressibility, which indicate structured systems. In vitro studies on bioadhesion revealed that the hexagonal mesophases increased the bioadhesiveness of the systems to the skin of the pig ear. An in vivo inflammation experiment showed that the curcumin-loaded hexagonal mesophase exhibited an anti-inflammatory activity as compared to the positive control (dexamethasone. The results suggest that this system has a potential to be used as a bioadhesive vehicle for the topical administration of curcumin. Therefore, it is possible to conclude that these systems can be used for the optimization of drug

The combined effects of e-beam irradiation and microwaves on starch, flour and ingredients

International Nuclear Information System (INIS)

Ferdes, O.S.; Martin, D.; Minea, R.; Tirlea, A.; Badea, M.

1998-01-01

The influences of both microwave field and electron beam irradiation, separately and combined, mainly on physical parameters of corn starch, wheat flour and black pepper were studied. These treatments have been used to achieve the hygienic and microbiological quality requirements of these materials and for their dehydration. The electron-beam irradiation has been carried out by using an ALIN-7 linear accelerator with the following parameters: electron mean energy 6 MeV, mean bean current 10 μA, pulse period 3.5 μs. repetition frequency 100 Hz. For microwave experiments, a special designed microwave applicator consisting of a special cavity, a power controlled generator with a 2.45 GHz standard frequency CW magnetron of 850 W maximum output power was used. The experiments were carried out in 5 variants: microwave treatment solely; electron beam irradiation solely; microwave treatment followed by electron beam irradiation; electron beam irradiation followed by microwave treatment; simultaneous microwave and electron beam treatment. The samples were treated by microwaves at 4 different power values from 250 W to 550 W for 5 different exposure times. The electron beam irradiation took place within the dose range of 1 - 10 kGy, at the same dose rate of approximately 2 kGy/min. The influence of these two physical fields on some common properties (r.h., pH), spectrophotometric (UV-VIS spectra), viscometric (rheograms) and microbiological (CFU/g) properties of the food materials was evaluated. A direct relationship between the variables was observed. The microwave effects are mainly thermal effects, although a non-thermal effect was also observed. The main microbiocidal action is due to the electron beam effect, although the microwave treatment affects sometimes significantly both the microbial population and its sensitivity to irradiation. The combined treatment indicates the presence of a synergistic effect of microwaves and electron-beams, which is of non

Evaluation of Changes in Index Properties of Lateritic Soil Stabilized with Fly Ash

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Agapitus AMADI

2010-12-01

Full Text Available For soils to be suitable in civil engineering projects, they must meet existing local requirements for index properties in addition to certain strength criteria. Typically, specifications limit these properties to some threshold values which in most cases are project specific. Some lateritic soils in their natural state need some treatment/modification to meet these specification requirements. The objective of this study was to evaluate changes in the index properties (i.e., particle size distribution, Atterberg limits and compaction characteristics of a residually derived lateritic soil following fly ash application. Lateritic soil – fly ash mixtures with up to 20% fly ash by dry weight of soil were tested and specimens for compaction characteristics were prepared at different compaction states (optimum, dry and wet of optimum moisture content and compacted using British Standard Light (BSL compactive effort. While soil – fly ash mixtures containing up to 15% fly ash classify as CL according to USCS classification system and plotted above A-line in the plasticity chart, it was observed that changes in the gradation characteristics of soil sample treated with 20% fly ash resulted in the alteration of its classification to ML as well as the crossing of the A- line to the silty region. The liquid limit (LL varied from 42.2 to 29.53% representing 70% reduction while the plasticity index (PI of specimen treated with 20% fly ash was 16% lower than that of natural soil. The optimum moisture content (OMC ranged from 17.36% for the natural soil to 18.34% for soil mixtures containing 20% fly ash which yielded dry unit weight of 17.2kN/m3 for the natural soil and 16.1kN/m3 for samples treated with 20% fly ash. From the study, useful data were obtained showing substantial and desirable changes in the properties of lateritic soil as a civil engineering material on application of fly ash.

Characterization of symptoms and edema distribution in premenstrual syndrome

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Tacani PM

2015-03-01

Full Text Available Pascale Mutti Tacani,1 Danielle de Oliveira Ribeiro,1 Barbara Evelyn Barros Guimarães,1 Aline Fernanda Perez Machado,2 Rogério Eduardo Tacani1,2 1Physical Therapy Department, São Camilo University Center, 2Physical Therapy Department, São Paulo City University (UNICID, São Paulo, Brazil Background: Premenstrual syndrome is a group of symptoms linked to the menstrual cycle, and edema is among these symptoms. Physiotherapy is often sought by many patients for the treatment of edema; however, for an adequate prescription of physiotherapeutic procedures, the distribution of edema throughout the body has yet to be characterized. Objective: To determine the most frequent symptoms and body regions that present with edema in women during the premenstrual period.Subjects and methods: Sixty women with a mean age of 24.6±4.7 years were evaluated during their premenstrual (between days 21 and 28 and menstrual period (between days 1 and 3, and the collected data included body mass, height, biotype (body-fat distribution, face, breast, limb-circumference measurements, and limb-volume estimate, and an adapted version of the Premenstrual Symptoms Screening Tool was used. Statistical analysis was performed using Student’s t-test and the test for equality of two proportions (P≤0.05.Results: Premenstrual syndrome was identified in 91.7% of the women, and the most frequent symptoms were irritability (73.33% and physical symptoms, including swelling (65%, and anxiety (58.3%. Edema was detected in the following areas: facial, epigastric, mammary, umbilical, and pubic, the mid-third of the arms, distal forearm, in both thighs and in the mid-third of the legs determined by circumference measurements, and in both upper and lower limbs, according to the estimated volume.Conclusion: In this study population, the most frequent symptoms were irritability, physical symptoms, and anxiety, with distribution of edema in the face, breast, abdomen, pubic area, distal

Sodium bicarbonate ingestion improves Yo-Yo intermittent recovery test 1 performance: a randomized crossover trial

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Dixon H

2017-04-01

Full Text Available Helen Dixon,1 Catherine E Baker,2 Julien S Baker,3 Susan Dewhurst,4 Lawrence D Hayes4 1School of Human Sciences, London Metropolitan University, London, 2English Institute of Sport, Bisham Abbey National Sports Center, Buckinghamshire, 3Institute of Clinical Exercise and Health Science, University of the West of Scotland, Hamilton, 4Department of Medical and Sport Sciences, University of Cumbria, Lancaster, UK Abstract: This study investigated the effect of sodium bicarbonate (NaHCO3– ingestion on the Yo-Yo intermittent recovery test 1 (IR1. We tested the hypothesis that acute ingestion of NaHCO3– would increase blood lactate concentrations [BLa], enhance performance, and reduce rating of perceived exertion (RPE in the Yo-Yo IR1. Eight recreationally active males (N=8, age: 26±4 yr, height: 178±6 cm, body mass: 82±10 kg participated in the Yo-Yo IR1 on two separate occasions, separated by 1 wk, in a randomized crossover design. Following familiarization, during seated rest, participants’ pretest [BLa] was taken, and participants then consumed either a placebo of 0.3 g·kg–1 body weight sodium chloride or 0.3 g·kg–1 body weight NaHCO3–. Sixty minutes postingestion, a standardized warm-up preceded the Yo-Yo IR1. Upon completion, postexercise [BLa] (mmol·L–1, RPE (arbitrary units and Yo-Yo IR1 time to fatigue (s were recorded. Paired t-test revealed a small but significant improvement in Yo-Yo IR1 performance under the NaHCO3– condition (610±267 sec, compared to the placebo condition (556±259 sec; p=0.01; Cohen’s d=0.20. [BLa] increased more under the NaHCO3– condition (1.6±0.7 to 17.5±5.2 mmol·L–1; p<0.001; Cohen’s d=4.29, compared to the placebo condition (2.0±0.7 to 11.5±5.0 mmol·L–1; p=0.001; Cohen’s d=2.66. Postexercise RPE was not significantly different between conditions. The results of this study suggest that acute NaHCO3– ingestion improves Yo-Yo IR1 performance without altering RPE, likely

Effect of nanoparticles binding ß-amyloid peptide on nitric oxide production by cultured endothelial cells and macrophages

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Orlando A

2013-04-01

Full Text Available Antonina Orlando,1 Francesca Re,1 Silvia Sesana,1 Ilaria Rivolta,1 Alice Panariti,1 Davide Brambilla,2 Julien Nicolas,2 Patrick Couvreur,2 Karine Andrieux,2 Massimo Masserini,1 Emanuela Cazzaniga1 1Department of Health Sciences, University of Milano-Bicocca, Monza, Italy; 2Institut Galien Paris Sud, University Paris-Sud, Châtenay-Malabry, France Background: As part of a project designing nanoparticles for the treatment of Alzheimer’s disease, we have synthesized and characterized a small library of nanoparticles binding with high affinity to the β-amyloid peptide and showing features of biocompatibility in vitro, which are important properties for administration in vivo. In this study, we focused on biocompatibility issues, evaluating production of nitric oxide by cultured human umbilical vein endothelial cells and macrophages, used as models of cells which would be exposed to nanoparticles after systemic administration. Methods: The nanoparticles tested were liposomes and solid lipid nanoparticles carrying phosphatidic acid or cardiolipin, and PEGylated poly(alkyl cyanoacrylate nanoparticles (PEG-PACA. We measured nitric oxide production using the Griess method as well as phosphorylation of endothelial nitric oxide synthase and intracellular free calcium, which are biochemically related to nitric oxide production. MTT viability tests and caspase-3 detection were also undertaken. Results: Exposure to liposomes did not affect the viability of endothelial cells at any concentration tested. Increased production of nitric oxide was detected only with liposomes carrying phosphatidic acid or cardiolipin at the highest concentration (120 µg/mL, together with increased synthase phosphorylation and intracellular calcium levels. Macrophages exposed to liposomes showed a slightly dose-dependent decrease in viability, with no increase in production of nitric oxide. Exposure to solid lipid nanoparticles carrying phosphatidic acid decreased viability in

Comparison between parameters of muscle performance and inflammatory biomarkers of non-sarcopenic and sarcopenic elderly women

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Lustosa LP

2017-08-01

Full Text Available Lygia Paccini Lustosa,1 Patrícia Parreira Batista,1 Daniele Sirineu Pereira,2 Leani Souza Máximo Pereira,1 Aline Scianni,1 Giane Amorim Ribeiro-Samora1 1Physical Therapy Department, Universidade Federal de Minas Gerais, Belo Horizonte, 2Physical Therapy Department, Universidade Federal de Alfenas, Alfenas, Brazil Background: Sarcopenia is a multifactorial geriatric syndrome with complex interrelationships. Increased plasma levels of inflammatory mediators increase the catabolic stimuli of the musculature, thereby causing a decrease in mass and muscular function. Objective: The objective of this study was to compare the performance of the knee extensors test (by isokinetic dynamometer and plasma levels of interleukin-6 (IL-6 and soluble receptors of tumor necrosis factor alpha (sTNFR1 between sarcopenics and non-sarcopenics community-dwelling elderly women residents of Brazil. Material and methods: The diagnosis of sarcopenia included measurements of body composition (by densitometry with dual energy source of X-ray, handgrip strength (by Jamar® dynamometer, and the usual gait velocity according to the recommendations of the European Working Group on Sarcopenia in Older People. In both sarcopenics and non-sarcopenics elderly women, we evaluated the muscle function by knee extensors test (using an isokinetic dynamometer Byodex System 4 Pro® at angular speeds of 60°/s and 180°/s and also we evaluated the plasma concentrations of IL-6 and sTNFR1. Comparisons of muscle performance between groups were carried out using mixed factorial ANOVA with post hoc Bonferroni test; sTNFR1 and IL-6 variables were analyzed by applying Mann–Whitney U test. Results: Statistical differences were observed between groups regarding muscle power (P=0.01, total work adjusted to body weight (P=0.01 at a rate of 180°/s, and plasma levels of sTNFR1 (P=0.01. Conclusion: Sarcopenic elder women showed lower performance of the lower limbs, especially at a higher speed

Relationship between napping during night shift work and household obligations of female nursing personnel

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Silva Costa A

2013-04-01

Full Text Available Aline Silva-Costa,1,2 Frida Marina Fischer,1 Rosane Harter Griep,2 Lúcia Rotenberg2 1School of Public Health, University of São Paulo, São Paulo, Brazil; 2Laboratory of Health, Environment and Education, Oswaldo Cruz Institute (Fiocruz, Rio de Janeiro, Brazil Abstract: Night shift employment involves displacing sleep to the daytime. For female workers, the opportunity for daytime sleep is influenced by routine housework demands, which aggravates sleep deprivation. Allowing naps to be taken during the night shift of work is a frequent practice at some hospitals and can help reduce the effects of sleep deprivation. We hypothesize that an association between domestic work and the length of naps during night work exists for nursing professionals. To test this hypothesis, two cross-sectional studies were conducted in two different hospitals. In Study 1, female workers answered questionnaires regarding sleeping habits, professional work, and housework demands. In Study 2, data regarding napping during shifts was obtained by actigraphy, a noninvasive method of monitoring the human sleep–wake cycle. The demand for the performance of housework was measured by (i domestic work hours (total time spent performing domestic work per week, and (ii domestic workload, which considers the degree of sharing domestic tasks and the number of people living at home. The populations from the two studies were subdivided into groups, based on the duration of napping at work. Data on naps were analyzed according to domestic demands, using the Mann–Whitney and Chi-squared tests. Among the two study populations (Studies 1 and 2, those in Study 2 were older, had shorter professional weekly work hours, worked more night shifts, and dedicated more time to housework. Significant associations were only found in Study 2, where greater time napping at work was associated with both greater time spent doing housework and greater domestic workload. The known benefits of

Reconstruction of Northeast Asian Deformation Integrated with Western Pacific Plate Subduction since 200 Ma

Science.gov (United States)

Liu, S.; Gurnis, M.; Ma, P.; Zhang, B.

2017-12-01

The configuration and kinematics of continental deformation and its marginal plate tectonics on the Earth's surface are intrinsic manifestations of plate-mantle coupling. The complex interactions of plate boundary forces result in plate motions that are dominated by slab pull and ridge push forces and the effects of mantle drag; these interactions also result in continental deformation with a complex basin-mountain architecture and evolution. The kinematics and evolution of the western Pacific subduction and northeast Asian continental-margin deformation are a first-order tectonic process whose nature and chronology remains controversial. This paper implements a "deep-time" reconstruction of the western Pacific subduction, continental accretion or collision and basin-mountain deformation in northeast Asia since 200 Ma based on a newly revised global plate model. The results demonstrate a NW-SE-oriented shortening from 200-137 Ma, a NWW-SEE-oriented extension from 136-101 Ma, a nearly N-S-oriented extension and uplift with a short-term NWW-SEE-oriented compressional inversion in northeast China from 100-67 Ma, and a NW-SE- and nearly N-S-oriented extension from 66 Ma to the present day. The western Pacific oceanic plate subducted forward under East Asia along Mudanjiang-Honshu Island during the Jurassic, and the trenches retreated to the Sikhote-Alin, North Shimanto, and South Shimanto zones from ca. 137-128 Ma, ca. 130-90 Ma, and in ca. 60 Ma, respectively. Our time-dependent analysis of plate motion and continental deformation coupling suggests that the multi-plate convergent motion and ocean-continent convergent orogeny were induced by advance subduction during the Jurassic and earliest Cretaceous. Our analysis also indicates that the intra-continent rifting and back-arc extension were triggered by trench retreat during the Cretaceous and that the subduction of oceanic ridge and arc were triggered by trench retreat during the Cenozoic. Therefore, reconstructing

Resistance exercise with different volumes: blood pressure response and forearm blood flow in the hypertensive elderly

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Brito AF

2014-12-01

Full Text Available Aline de Freitas Brito,1 Caio Victor Coutinho de Oliveira,2 Maria do Socorro Brasileiro-Santos,1 Amilton da Cruz Santos1 1Physical Education Department, 2Research Laboratory for Physical Training Applied to Performance and Health, Federal University of Paraíba, João Pessoa, Brazil Background: The purpose of this study was to evaluate the effect of two sessions of resistance exercise with different volumes on post-exercise hypotension, forearm blood flow, and forearm vascular resistance in hypertensive elderly subjects.Methods: The study was conducted with ten hypertensive elderly (65±3 years, 28.7±3 kg/m2 subjected to three experimental sessions, ie, a control session, exercise with a set (S1, and exercise with three sets (S3. For each session, the subjects were evaluated before and after intervention. In the pre-intervention period, blood pressure, forearm blood flow, and forearm vascular resistance were measured after 10 minutes of rest in the supine position. Thereafter, the subjects were taken to the gym to perform their exercise sessions or remained at rest during the same time period. Both S1 and S3 comprised a set of ten repetitions of ten exercises, with an interval of 90 seconds between exercises. Subsequently, the measurements were again performed at 10, 30, 50, 70, and 90 minutes of recovery (post-intervention in the supine position.Results: Post-exercise hypotension was greater in S3 than in S1 (systolic blood pressure, −26.5±4.2 mmHg versus −17.9±4.7 mmHg; diastolic blood pressure, −13.8±4.9 mmHg versus −7.7±5 mmHg, P<0.05. Similarly, forearm blood flow and forearm vascular resistance changed significantly in both sessions with an increase and decrease, respectively, that was more evident in S3 than in S1 (P<0.05.Conclusion: Resistance exercises with higher volume were more effective in causing post-exercise hypotension, being accompanied by an increase in forearm blood flow and a reduction of forearm vascular

Method for pulse to pulse dose reproducibility applied to electron linear accelerators

International Nuclear Information System (INIS)

Ighigeanu, D.; Martin, D.; Oproiu, C.; Cirstea, E.; Craciun, G.

2002-01-01

An original method for obtaining programmed beam single shots and pulse trains with programmed pulse number, pulse repetition frequency, pulse duration and pulse dose is presented. It is particularly useful for automatic control of absorbed dose rate level, irradiation process control as well as in pulse radiolysis studies, single pulse dose measurement or for research experiments where pulse-to-pulse dose reproducibility is required. This method is applied to the electron linear accelerators, ALIN-10 of 6.23 MeV and 82 W and ALID-7, of 5.5 MeV and 670 W, built in NILPRP. In order to implement this method, the accelerator triggering system (ATS) consists of two branches: the gun branch and the magnetron branch. ATS, which synchronizes all the system units, delivers trigger pulses at a programmed repetition rate (up to 250 pulses/s) to the gun (80 kV, 10 A and 4 ms) and magnetron (45 kV, 100 A, and 4 ms).The accelerated electron beam existence is determined by the electron gun and magnetron pulses overlapping. The method consists in controlling the overlapping of pulses in order to deliver the beam in the desired sequence. This control is implemented by a discrete pulse position modulation of gun and/or magnetron pulses. The instabilities of the gun and magnetron transient regimes are avoided by operating the accelerator with no accelerated beam for a certain time. At the operator 'beam start' command, the ATS controls electron gun and magnetron pulses overlapping and the linac beam is generated. The pulse-to-pulse absorbed dose variation is thus considerably reduced. Programmed absorbed dose, irradiation time, beam pulse number or other external events may interrupt the coincidence between the gun and magnetron pulses. Slow absorbed dose variation is compensated by the control of the pulse duration and repetition frequency. Two methods are reported in the electron linear accelerators' development for obtaining the pulse to pulse dose reproducibility: the method

Association between coping mechanisms and adherence to diabetes-related self-care activities: a cross-sectional study

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Albai A

2017-07-01

Full Text Available Alin Albai,1 Alexandra Sima,1 Ion Papava,2 Deiana Roman,1 Bogdan Andor,3 Mihai Gafencu4 1Second Department of Internal Medicine, 2Department of Neurosciences, 3Department of Orthopedics, 4Department of Pediatrics, Victor Babeş University of Medicine and Pharmacy, Timisoara, Romania Abstract: In the overall management of the most chronic diseases, including diabetes mellitus (DM, adherence to recommended disease-related self-care activities is of paramount importance. The diagnosis and presence of a chronic disease may be considered a difficult and stressful situation in life, a situation in which coping mechanisms are psychological processes developed at a conscious level to manage these situations. This study aimed to explore the possible relationship between the dominance of one of the four major coping styles and adherence to diabetes-related self-care activities (DRSCAs in the population of patients with type 2 DM (T2DM. In a cross-sectional consecutive-case population-based study design, 126 patients previously diagnosed with T2DM were enrolled. Coping mechanisms were evaluated using the Cope scale inventory, which identifies the dominant coping mechanism: problem-, emotion-, social support-, or avoidance-focused. The quality of DRSCA was evaluated using the summary of diabetes self-care activities questionnaire, in which a higher score was associated with improved adherence. In the study cohort, 45 patients (35.7% had problem-focused coping, 37 (29.4% had emotion-focused coping, 32 (25.4% social support-focused coping, and 12 (9.5% had avoidance-focused coping. Patients with emotion-focused coping had the highest level (P=0.02 of DRSCA (median 44 points, followed by patients with social support-focused coping (median 40 points and problem-focused coping (median 36 points, while patients with avoidance-focused coping had the lowest SDSCA total score (33 points. The type of dominant coping mechanism has a significant impact on the quality

Librarians View Instruction as Integral to Their Professional Identities. A Review of: Julien, H., & Genuis, S. K. (2011. Librarians’ experience of the teaching role: A national survey of librarians. Library & Information Science Research, 33(2, 103-111. doi: 10.1016/j.lisr.2010.09.005

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Ann Medaille

2011-01-01

Full Text Available Objective – To explore the ways that professional and non-professional library staff experience and relate to their instructional roles.Design – Online survey.Setting – All types of Canadian libraries, including public, school, post-secondary, medical, special, and other libraries.Subjects – A total of 788 library staff persons with instructional responsibilities.Methods – In 2009, the authors constructed a 20-minute anonymous survey that contained questions about the nature of librarians’ instructional work, their preparation for doing instruction, and their experiences as instructors. Subjects were recruited via several electronic mail lists. The authors used SPSS to analyze the quantitative data and NVivo to analyze the qualitative data.Main Results – The study found that the majority of subjects believed instruction to be integral to their professional identities, although some viewed it as an imposition. The nature of instructional work varied greatly, but included short presentations; a series of sessions; semester-length courses; and one-on-one instruction. Subjects prepared for instruction through on-the-job training; reading professional literature; attending workshops and conferences; taking a formal course in instruction; and other methods. On the whole, training helped library staff to feel more prepared for teaching and to embrace instructional work as integral to their professional identities. Study participants derived enjoyment from instruction in the form of satisfaction with facilitating student learning; relationship building; personal development; task variety; and appreciation of the heightened profile of library staff. Subjects also described several barriers to teaching, including administrative, technological, and logistical barriers; client and faculty interactions; and interpersonal challenges such as nervousness or lack of preparation. Finally, subjects described the ways that instruction has changed with the impact of new technologies, increased expectations, and changing pedagogical practices. Conclusion – Library administrators should support the teaching duties of librarians and library staff by helping to provide them with adequate preparation time, resources, emotional support, and training. In addition, formal preparation for instruction should be integrated into professional library training programs, including MLIS programs, to better prepare librarians and other library staff to participate in information literacy instruction.

Psychological consequences of childhood obesity: psychiatric comorbidity and prevention

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Rankin J

2016-11-01

Full Text Available Jean Rankin,1 Lynsay Matthews,2 Stephen Cobley,3 Ahreum Han,3 Ross Sanders,3 Huw D Wiltshire,4 Julien S Baker5 1Department of Maternal and Child Health, University of the West of Scotland, Paisley, 2MRC/CSO Social and Public Health Sciences Unit, Institute of Health and Wellbeing, University of Glasgow, Glasgow, Scotland; 3Department of Exercise and Sport Science, University of Sydney, Sydney, Australia; 4Cardiff School of Sport/Ysgol Chwaraeon Caerdydd, Cardiff Metropolitan University, Cardiff, UK; 5School of Science and Sport, Institute of Clinical Exercise and Health Science, University of the West of Scotland, Hamilton, Scotland Abstract: Childhood obesity is one of the most serious public health challenges of the 21st century with far-reaching and enduring adverse consequences for health outcomes. Over 42 million children <5 years worldwide are estimated to be overweight (OW or obese (OB, and if current trends continue, then an estimated 70 million children will be OW or OB by 2025. The purpose of this review was to focus on psychiatric, psychological, and psychosocial consequences of childhood obesity (OBy to include a broad range of international studies. The aim was to establish what has recently changed in relation to the common psychological consequences associated with childhood OBy. A systematic search was conducted in MEDLINE, Web of Science, and the Cochrane Library for articles presenting information on the identification or prevention of psychiatric morbidity in childhood obesity. Relevant data were extracted and narratively reviewed. Findings established childhood OW/OBy was negatively associated with psychological comorbidities, such as depression, poorer perceived lower scores on health-related quality of life, emotional and behavioral disorders, and self-esteem during childhood. Evidence related to the association between attention-deficit/hyperactivity disorder (ADHD and OBy remains unconvincing because of various findings

Apresentação

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Os Editores

2004-12-01

Full Text Available Este número da Significação segue os parâmetros já definidos pela revista, isto é, integra um conjunto de trabalhos de pesquisadores de diferentes Programas de Pós-Graduação do País e ensaios de investigadores estrangeiros que se publicam pela primeira vez, dois deles na língua original e um terceiro traduzido para o português. Quanto à temática, os textos aqui reunidos lidam com assuntos que nos parecem de interesse considerando as tendências atuais dos estudos da comunicação e, ainda, a relevância da epistemologia para a análise e interpretação das metáforas visuais, assim como das mudanças porque vem passando o conceito de sujeito nas ciências humanas. Isso fica claro se, por exemplo, nos adentramos na leitura e discussão dos fundamentos narratológicos, no equacionamento da metodologia posta em prática nas abordagens de discursos fílmicos ou da apropriação caricatural e grotesca da crise do sujeito que se manifesta no espetáculo midiático. Somem-se a isso os esforços destinados a nos dar, de um lado, um panorama diacrônico dos aspectos fundamentais do cinema mexicano moderno e, de outro, uma visão predominantemente sincrônica de um tema que funciona como entremeio no cinema espanhol contemporâneo. Em seu conjunto, a diversidade de tópicos abordados define, como não poderia deixar de ser, eixos comuns em torno dos quais giram pontos de vista cujas diferenças não impedem o diálogo, traço característico que orienta as particularidades deste periódico. É de se ressaltar, também, a preocupação com o estudo da imagem a partir das peculiaridades das etimologias iconográficas, pressuposto que, a nosso ver, abre novas perspectivas para a crítica das mensagens visuais. Mas este número, levando em conta a já longa trajetória da revista, se toma, sobretudo, singular pelo fato de publicar, pela primeira vez e em português, um texto pouco conhecido de Algirdas Julien Greimas, traduzido diretamente do

SEISMODYNAMICS AND DEEP INTERNAL ORIGIN OF THE NORTH CHINA ZONE OF STRONG EARTHQUAKES

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Andrey A. Stepashko

2011-01-01

Full Text Available Space-and-time regularities of seismicity of the North China (Tan-Lu zone are studies, and tectonic nature of strong earthquakes is analyzed. The concept of its genesis is still a matter of debate as this zone is located in the centre of the ancient SinoKorean craton, i.e. thousand kilometers away from convergent margins of Eurasia and the Pacific оcean and IndoAustralian plates (Figure 1. The information on the regional cycling dynamics [Xu, Deng, 1996] is updated. Two cycles, in which strong earthquakes (14 shocks with М≥7.0 occurred in the region under study, are distinguished, i.e. from 1500 to 1700, and from 1800 to 1980 (Figure 2. The seismodynamics of the North China zone is consistent with the Circum Pacific оcean deformation wave that occurs once in 300 years at the margin between Asia and the ocean and thus causes the strongest earthquakes (М≥8.8 and eruptions of volcanoes in the Pacific оcean belt [Vikulin et al., 2009, 2010]. This wave came to the northern regions of China in the years of 1500 and 1800 (Figure 3 and triggered seismic activity cycles. The second factor predetermining the seismicity of the Northern China is a specific structure of the region which can manifest seismic activity due to the impact of deformation waves. The genesis of the metastable structure of the region is related to tectonic restructuring of the lithosphere of the SinoKorean craton due to shear displacements in the Tan-Lu megazone. Regional variations of compositions of mantle xenoliths of the Sikhote Alin orogeny demonstrate that the latent strike of the Tan-Lu faults can be traced across the south-eastern areas of Russia to the Tatar Strait. These faults are borders of the Vshaped mantle block (400 x 1500 km (Figure 5, which composition is characterized by an anomalous content of iron and a low depletion of peridotites. The tectonic mantle block maintains its activity; being impacted by compression from the west, it is squeezed out towards

Spirituality in childhood cancer care

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Lima NN

2013-10-01

Full Text Available Nádia Nara Rolim Lima,1 Vânia Barbosa do Nascimento,1 Sionara Melo Figueiredo de Carvalho,1 Modesto Leite Rolim Neto,2 Marcial Moreno Moreira,2 Aline Quental Brasil,2 Francisco Telésforo Celestino Junior,2 Gislene Farias de Oliveira,2 Alberto Olavo Advíncula Reis3 1Health Sciences Postgraduate Program, ABC Region Medical School, Santo André, São Paulo, Brazil; 2Department of Medicine, Federal University of Ceará, Barbalha, Ceará, Brazil; 3Public Health Postgraduate Program, University of São Paulo, São Paulo, Brazil Abstract: To deal with the suffering caused by childhood cancer, patients and their families use different coping strategies, among which, spirituality appears a way of minimizing possible damage. In this context, the purpose of the present study was to analyze the influence of spirituality in childhood cancer care, involving biopsychosocial aspects of the child, the family, and the health care team facing the disease. To accomplish this purpose, a nonsystematic review of literature of articles on national and international electronic databases (Scientific Electronic Library Online [SciELO], PubMed, and Latin American and Caribbean Health Sciences Literature [LILACS] was conducted using the search terms “spirituality,” “child psychology,” “child,” and “cancer,” as well as on other available resources. After the search, 20 articles met the eligibility criteria and were included in the final sample. Our review showed that the relation between spirituality and health has lately become a subject of growing interest among researchers, as a positive influence of spirituality in the people's welfare was noted. Studies that were retrieved using the mentioned search strategy in electronic databases, independently assessed by the authors according to the systematic review, showed that spirituality emerges as a driving force that helps pediatric patients and their families in coping with cancer. Health care workers

Ten good reasons to practice ultrasound in critical care.

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Lichtenstein, Daniel; van Hooland, Simon; Elbers, Paul; Malbrain, Manu L N G

2014-01-01

Over the past decade, critical care ultrasound has gained its place in the armamentarium of monitoring tools. A greater understanding of lung, abdominal, and vascular ultrasound plus easier access to portable machines have revolutionised the bedside assessment of our ICU patients. Because ultrasound is not only a diagnostic test, but can also be seen as a component of the physical exam, it has the potential to become the stethoscope of the 21st century. Critical care ultrasound is a combination of simple protocols, with lung ultrasound being a basic application, allowing assessment of urgent diagnoses in combination with therapeutic decisions. The LUCI (Lung Ultrasound in the Critically Ill) consists of the identification of ten signs: the bat sign (pleural line); lung sliding (seashore sign); the A-lines (horizontal artefact); the quad sign and sinusoid sign indicating pleural effusion; the fractal and tissue-like sign indicating lung consolidation; the B-lines and lung rockets indicating interstitial syndromes; abolished lung sliding with the stratosphere sign suggesting pneumothorax; and the lung point indicating pneumothorax. Two more signs, the lung pulse and the dynamic air bronchogram, are used to distinguish atelectasis from pneumonia. The BLUE protocol (Bedside Lung Ultrasound in Emergency) is a fast protocol (respiratory failure. With this protocol, it becomes possible to differentiate between pulmonary oedema, pulmonary embolism, pneumonia, chronic obstructive pulmonary disease, asthma, and pneumothorax, each showing specific ultrasound patterns and profiles. The FALLS protocol (Fluid Administration Limited by Lung Sonography) adapts the BLUE protocol to be used in patients with acute circulatory failure. It makes a sequential search for obstructive, cardiogenic, hypovolemic, and distributive shock using simple real-time echocardiography in combination with lung ultrasound, with the appearance of B-lines considered to be the endpoint for fluid therapy

Geology and ore deposits of the Section 23 Mine, Ambrosia Lake District, New Mexico

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Granger, H.C.; Santos, E.S.

1982-01-01

The section 23 mine is one of about 18 large uranium mines opened in sandstones of the fluvial Westwater Canyon Member of the Jurassic Morrison Formation in the Ambrosia Lake mining district during the early 1960s. The Ambrosia Lake district is one of several mining districts within the Grants mineral belt, an elongate zone containing many uranium deposits along the southern flank of the San Juan basin. Two distinct types of ore occur in the mine. Primary ore occurs as peneconcordant layers of uranium-rich authigenic organic matter that impregnates parts of the reduced sandstone host rocks and which are typically elongate in an east-southeast direction subparallel both to the sedimentary trends and to the present-day regional strike of the strata. These are called prefault or trend ores because of their early genesis and their elongation and alinement. A second type of ore in the mine is referred to as postfault, stacked, or redistributed ore. Its genesis was similar to that of the roll-type deposits in Tertiary rocks of Wyoming and Texas. Oxidation, related to the development of a large tongue of oxidized rock extending from Gallup to Ambrosia Lake, destroyed much of the primary ore and redistributed it as massive accumulations of lower grade ores bordering the redox interface at the edge of the tongue. Host rocks in the southern half of sec. 23 (T. 14 N., R. 10 W.) are oxidized and contain only remnants of the original, tabular, organic-rich ore. Thick bodies of roll-type ore are distributed along the leading edge of the oxidized zone, and pristine primary ore is found only near the north edge of the section. Organic matter in the primary ore was derived from humic acids that precipitated in the pores of the sandstones and fixed uranium as both coffinite and urano-organic compounds. Vanadium, molybdenum, and selenium are also associated with the ore. The secondary or roll-type ores are essentially free of organic carbon and contain uranium both as coffinite and

Determining the Location of the Snowline in an Externally-Photoevaporated Solar Nebula

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Kalyaan, Anusha; Desch, Steven

2015-11-01

, 1405-1407 [4] Sasselov, D.D., & Lecar, M., (2000) ApJ 528, 995-998 [5] Cuzzi, J .N ., & Zahnle, K .J., (2004) ApJ 614, 490-496 [6] Ciesla, F. J., & Cuzzi, J. N. (2006) Icarus 181, 178-204 [7] Desch S.J.(2012)LPSC abstract #2770 [8] Kalyaan, A. et al.(in review)

The psychosocial impact of acne, vitiligo, and psoriasis: a review

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Nguyen CM

2016-10-01

Full Text Available Catherine M Nguyen,1 Kourosh Beroukhim,2 Melissa J Danesh,3 Aline Babikian,4 John Koo,3 Argentina Leon3 1University of California, Irvine School of Medicine, Irvine, 2David Geffen School of Medicine at UCLA, Los Angeles, 3Department of Dermatology, University of California San Francisco School of Medicine, San Francisco, 4Touro University College of Osteopathic Medicine, Vallejo, CA, USA Introduction: Chronic skin conditions have been well reported to affect a patient's quality of life on multiple dimensions, including the psychosocial domain. Psychosocial is defined as the interrelation of social factors with an individual's thoughts and behavior. The assessment of the psychosocial impact of skin disease on a patient can help direct the dermatologists' treatment goals. To evaluate the psychosocial impact of skin disease, we conducted a review of the literature on three skin conditions with onsets at various stages of life: acne, vitiligo, and psoriasis. Methods: A PubMed search was conducted in March 2015 using the terms “psychosocial” AND “acne”, “psychosocial” AND “vitiligo”, and “psychosocial” AND “psoriasis”. The results were limited to articles published in English in the past 5 years studying patients of all ages. Results and their references were evaluated for relevance according to their discussion of psychosocial qualities in their patients and the validity of psychosocial assessments. The search for acne yielded 51 results, and eleven were found to be relevant; vitiligo yielded 30 results with ten found to be relevant; and psoriasis yielded 70 results with seven found to be relevant. Results: According to the articles evaluated, 19.2% of adolescent patients with acne were affected in their personal and social lives. Social phobia was present in 45% of patients with acne compared to 18% of control subjects. Race and sex played a role in self-consciousness and social perceptions of the disease. Vitiligo

Magnetic and electronic properties of some actinide intermetallic compounds

International Nuclear Information System (INIS)

Yaar, Ilan

1992-06-01

The electronic structure and magnetic properties of the light actinide intermetallic compounds are often related to interplay between localized and itinerant (band like) behavior of the 5f- electrons. In the present work, the properties of some actinide, mainly Np, intermetallic compounds were studied by Mossbauer effect, ac and dc susceptibility, X-ray and Neutron diffraction techniques. 1. NpX 2 (X=Ga,Si) - Both compounds order ferromagnetically at TC=55(2) and 48(2) K respectively. A comparison of our data with the results for other NpX 2 (X=Al,As,Sb,Tl) compounds indicates that NpGa 2 is a highly localized 5f electron system, whereas in NpSi 2 the 5f electrons are partially delocalized. The magnetic properties of NpX 2 compounds can neither be consistently explained within the conventional crystal electric field picture (CEF) nor by takink into account hybridization dressing of local spin density models. 2. NpX 3 (X=Ga,Si,In,Al) in the cubic AuCu 3 (Pm3m) crystallographic structure - From the Mossbauer isomer shift (IS) data we argue that the Np ion in the NpX 3 family is close to the formal 3+ (5I 4 ) charge state. The magnetic moment of the Np in NpSi 3 is totally suppressed whereas in NpGa 3 and NpAl 3 a localized (narrow band) moment is established. However, in NpIn 3 at 4.2 K, a modulated magnetic moment (0-1.5μB) is observed. Comparing the magnetic behavior of the NpX 3 family (X=Si,Ge,Ga, Al,In and Sn), we find an impressive variation of the magnetic properties, from temperature independent paramagnetism (TIP), localized and modulated ordered moments, to the formation of a concentrated Kondo lattice. Hybridization of 5f electrons with ligand electrons appears to play a crucial role in establishing these magnetic properties. However, at present a consistent theoretical picture can not be drawn. 3. XFe 4 Al 8 (X=Ho,Np,U) spin galss (SG) systems in the ThMn 12 (I 4 /mmm) crystallographic structure - Localized and itinerant behaviour of the f electrons

Conversion et culture dans le monde grec du IVe siècle ap. J.-C. Conversion and culture in the 4th century AD Greek world

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Pierre-Louis Malosse

2009-10-01

Full Text Available Rarement la conversion – concept, événement, acte – a tenu une place telle qu’au IVe siècle après Jésus-Christ, dans les années qui mènent de la conversion d’un empereur (Constantin à celle de l’empire. Dans le monde oriental, dominé par la culture hellénique, la conversion religieuse rencontre un modèle depuis longtemps reconnu, celui de la conversion philosophique (ou à la philosophie. Entre l'une et l'autre, il existe une certaine porosité, plus ou moins consciente, comme l'attestent en des directions opposées le cas des milieux philosophiques alexandrins – y compris peut-être Arios –, ou celui de Julien. D'autre part, à l'orée du IVe siècle, la conversion chrétienne a déjà une longue histoire. La nouveauté de l'Antiquité tardive, outre le changement d'échelle, du petit nombre à la masse et du marginal à l'officiel avec le soutien de l'État, est de poser la question du rapport de la conversion religieuse à la culture traditionnelle, question qui ne se posait pas à propos de la conversion philosophique, puisque celle-ci était une composante de cette culture, question qui se pose particulièrement au moment où les convertis prétendent prendre en charge la culture. Plus précisément, il s'agit d'une confrontation avec la paideia, concept qui embrasse et unit étroitement culture et éducation. Chez les auteurs qui s’y réfèrent, que ce soit explicitement ou implicitement, la conversion se définit par rapport à la paideia tour à tour en termes d’exclusion, de concurrence et de complémentarité.Conversion –as a concept, as an event and as a deed – was seldom as imporant as it was during Forth Century AD, from the conversion of an emperor (Constantine to the conversion of the whole Empire. In the Greek speaking and thinking East, religious conversion came across philosophical conversion model, which had been known and admitted for a long time. So, philosophical conversion could

Anti-inflammatory and immunomodulatory effects of Aquaphilus dolomiae extract on in vitro models

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Aries MF

2016-11-01

Full Text Available Marie-Françoise Aries,1 Hélène Hernandez-Pigeon,1 Clémence Vaissière,1 Hélène Delga,1 Antony Caruana,1 Marguerite Lévêque,1 Muriel Bourrain,1,2 Katia Ravard Helffer,1 Bertrand Chol,3 Thien Nguyen,1 Sandrine Bessou-Touya,1 Nathalie Castex-Rizzi1 1Pierre Fabre Dermo-Cosmétique, Centre de Recherche & Développement Pierre Fabre, Toulouse, 2Sorbonne Universités, UPMC Univ Paris 06, CNRS, Laboratoire de Biodiversité et Biotechnologies Microbiennes (LBBM, Observatoire Océanologique, Banyuls/Mer, France; 3Centre d’Immunologie Pierre Fabre, Saint-Julien-en-Genevois, France Background: Atopic dermatitis (AD is a common skin disease characterized by recurrent pruritic inflammatory skin lesions resulting from structural and immune defects of the skin barrier. Previous studies have shown the clinical efficacy of Avène thermal spring water in AD, and a new microorganism, Aquaphilus dolomiae was suspected to contribute to these unique properties. The present study evaluated the anti-inflammatory, antipruritic, and immunomodulatory properties of ES0, an original biological extract of A. dolomiae, in immune and inflammatory cell models in order to assess its potential use in the treatment of AD.Materials and methods: An ES0 extract containing periplasmic and membrane proteins, peptides, lipopolysaccharides, and exopolysaccharides was obtained from A. dolomiae. The effects of the extract on pruritus and inflammatory mediators and immune mechanisms were evaluated by using various AD cell models and assays.Results: In a keratinocyte model, ES0 inhibited the expression of the inflammatory mediators, thymic stromal lymphopoietin, interleukin (IL-18, IL-4R, IL-8, monocyte chemoattractant protein-3, macrophage inflammatory protein-3α, and macrophage-derived chemokine and induced the expression of involucrin, which is involved in skin barrier keratinocyte terminal differentiation. In addition, ES0 inhibited protease-activated receptor-2 activation in

The Adverse Drug Reactions from Patient Reports in Social Media Project: Five Major Challenges to Overcome to Operationalize Analysis and Efficiently Support Pharmacovigilance Process.

Science.gov (United States)

Bousquet, Cedric; Dahamna, Badisse; Guillemin-Lanne, Sylvie; Darmoni, Stefan J; Faviez, Carole; Huot, Charles; Katsahian, Sandrine; Leroux, Vincent; Pereira, Suzanne; Richard, Christophe; Schück, Stéphane; Souvignet, Julien; Lillo-Le Louët, Agnès; Texier, Nathalie

2017-09-21

, syntactic rules, and post-analysis processing, and (5) proposed a component-based architecture that allows storage of big data and accessibility to third-party applications through Web services. We demonstrated the feasibility of implementing a component-based architecture that allows collection of patient posts on the Internet, near real-time processing of those posts including annotation, and storage in big data structures. In the next steps, we will evaluate the posts identified by the system in social media to clarify the interest and relevance of such approach to improve conventional pharmacovigilance processes based on spontaneous reporting. ©Cedric Bousquet, Badisse Dahamna, Sylvie Guillemin-Lanne, Stefan J Darmoni, Carole Faviez, Charles Huot, Sandrine Katsahian, Vincent Leroux, Suzanne Pereira, Christophe Richard, Stéphane Schück, Julien Souvignet, Agnès Lillo-Le Louët, Nathalie Texier. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 21.09.2017.

Canadian Public Library Users are Unaware of Their Information Literacy Deficiencies as Related to Internet Use and Public Libraries are Challenged to Address These Needs. A Review of: Julien, Heidi and Cameron Hoffman. “Information Literacy Training in Canada’s Public Libraries.” Library Quarterly 78.1 (2008: 19‐41.

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Martha Ingrid Preddie

2009-12-01

Full Text Available Objective – To examine the role of Canada’s public libraries in information literacy skills training, and to ascertain the perspectives of public library Internet users with regard to their experiences of information literacy.Design – Qualitative research using semi‐structured interviews and observations.Setting – Five public libraries in Canada.Subjects – Twenty‐eight public library staff members and twenty‐five customers. Methods – This study constituted the second phase of a detailed examination of information literacy (IL training in Canadian public libraries. Five public libraries located throughout Canada were selected for participation. These comprised a large central branch of a public library located in a town with a population of approximately two million, a main branch of a public library in an urban city of about one million people, a public library in a town with a population of about 75,000, a library in a town of 900 people and a public library located in the community center of a Canadian First Nations reserve that housed a population of less than 100 persons. After notifying customers via signage posted in the vicinity of computers and Internet access areas, the researchers observed each patron as they accessed the Internet via library computers. Observations focused on the general physical environment of the Internet access stations, customer activities and use of the Internet, as well as the nature and degree of customer interactions with each other and with staff. Photographs were also taken and observations were recorded via field notes. The former were analyzed via qualitative content analysis while quantitative analysis was applied to the observations. Additionally, each observed participant was interviewed immediately following Internet use. Interview questions focused on a range of issues including the reasons why customers used the Internet in public libraries, customers’ perceptions about their level of information literacy and their feelings with regard to being information literate, the nature of their exposure to IL training, the benefits they derived from such training, and their desire for further training. Public service librarians and other staff were also interviewed in a similar manner. These questions sought to ascertain staff views on the role of the public library with regard to IL training; perceptions of the need for and expected outcomes of such training; as well as the current situation pertinent to the provision of IL skills training in their respective libraries in terms of staff competencies, resource allocation, and the forms of training and evaluation. Interviews were recorded and transcribed. Data were interpreted via qualitative content analysis through the use of NVivo software.Main Results – Men were more frequent users of public library computers than women, outnumbering them by a ratio ranging from 2:1 to 3.4:1. Customers appeared to be mostly under the age of 30 and of diverse ethnicities. The average income of interviewed customers was less than the Canadian average. The site observations revealed that customers were seen using the Internet mainly for the purposes of communication (e.g., e‐mail, instant messaging, online dating services. Such use was observed 78 times in four of the libraries. Entertainment accounted for 43 observations in all five sites and comprised activities such as online games, music videos, and movie listings. Twenty‐eight observations involved business/financial uses (e.g., online shopping, exploration of investment sites, online banking. The use of search engines (25 observations, news information (23, foreign language and forum websites (21, and word processing were less frequently observed. Notably, there were only 20 observed library‐specific uses (e.g., searching online catalogues, online database and library websites. Customers reported that they used the Internet mainly for general web searching and for e‐mail.It was also observed that in general the physical environment was not conducive to computer use due to uncomfortable or absent seating and a lack of privacy. Additionally, only two sites had areas specifically designated for IL instruction.Of the 25 respondents, 19 reported at least five years experience with the Internet, 9 of whom cited experience of 10 years or more. Self‐reported confidence with the Internet was high: 16 individuals claimed to be very confident, 7 somewhat confident, and only 2 lacking in confidence. There was a weak positive correlation between years of use and individuals’ reported levels of confidence.Customers reported interest in improving computer literacy (e.g., keyboarding ability and IL skills (ability to use more sources of information. Some expressed a desire “to improve certain personal attitudes” (30, such as patience when conducting Internet searches. When presented with the Association of College and Research Libraries’ definition of IL, 13 (52% of those interviewed claimed to be information literate, 8 were ambivalent, and 4 admitted to being information illiterate. Those who professed to be information literate had no particular feeling about this state of being, however 10 interviewees admitted feeling positive about being able to use the Internet to retrieve information. Most of those interviewed (15 disagreed that a paucity of IL skills is a deterrent to “accessing online information efficiently and effectively” (30. Eleven reported development of information skills through self teaching, while 8 cited secondary schools or tertiary educational institutions. However, such training was more in terms of computer technology education than IL. Eleven of the participants expressed a desire for additional IL training, 5 of whom indicated a preference for the public library to supply such training. Customers identified face‐to‐face, rather than online, as the ideal training format. Four interviewees identified time as the main barrier to Internet use and online access.As regards library staff, 22 (78.6% of those interviewed posited IL training as an important role for public libraries. Many stated that customers had been asking for formal IL sessions with interest in training related to use of the catalogue, databases, and productivity software, as well as searching the web. Two roles were identified in the context of the public librarian as a provider of IL: “library staff as teachers/agents of empowerment and library staff as ‘public parents’” (32. The former was defined as supporting independent, lifelong learning through the provision of IL skills, and the latter encompassing assistance, guidance, problem solving, and filtering of unsuitable content.Staff identified challenges to IL training as societal challenges (e.g., need for customers to be able to evaluate information provided by the media, the public library’s role in reducing the digital divide, institutional (e.g., marketing of IL programs, staff constraints, lack of budget for IL training, infrastructural (e.g., limited space, poor Internet access in library buildings and pedagogical challenges, such as differing views pertinent to the philosophy of IL, as well as the low levels of IL training to which Canadian students at all levels had been previously exposed. Despite these challenges library staff acknowledged positive outcomes resulting from IL training in terms of customers achieving a higher level of computer literacy, becoming more skillful at searching, and being able to use a variety of information sources. Affective benefits were also apparent such as increased independence and willingness to learn. Library staff also identified life expanding outcomes, such as the use of IL skills to procure employment.In contrast to customer self‐perception, library staff expressed that customers’ IL skills were low, and that this resulted in their avoidance of “higher‐level online research” and the inability to “determine appropriate information sources” (36. Several librarians highlighted customers’ incapacity to perform simple activities such as opening an email account. Library staff also alluded to customer’s reluctance to ask them for help.Libraries in the study offered a wide range of training. All provided informal, personalized training as needed. Formal IL sessions on searching the catalogue, online searching, and basic computer skills were conducted by the three bigger libraries. A mix of librarians and paraprofessional staff provided the training in these libraries. However, due to a lack of professional staff, the two smaller libraries offered periodic workshops facilitated by regional librarians. All the libraries lacked a defined training budget. Nonetheless, the largest urban library was well‐positioned to offer IL training as it had a training coordinator, a training of trainers program, as well as technologically‐equipped training spaces. The other libraries in this study provided no training of trainers programs and varied in terms of the adequacy of spaces allocated for the purpose of training. The libraries also varied in terms of the importance placed on the evaluation of IL training. At the largest library evaluation forms were used to improve training initiatives, while at the small town library “evaluations were done anecdotally” (38.Conclusion – While Internet access is available and utilized by a wide cross section of the population, IL skills are being developed informally and not through formal training offered by public libraries. Canadian public libraries need to work to improve information literacy skills by offering and promoting formal IL training programs.

Methotrexate carried in lipid core nanoparticles reduces myocardial infarction size and improves cardiac function in rats

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Maranhão RC

2017-05-01

Full Text Available Raul C Maranhão,1,2 Maria C Guido,1 Aline D de Lima,1 Elaine R Tavares,1 Alyne F Marques,1 Marcelo D Tavares de Melo,3 Jose C Nicolau,3 Vera MC Salemi,3 Roberto Kalil-Filho3 1Laboratory of Metabolism and Lipids, 2Faculty of Pharmaceutical Sciences, 3Heart Failure Unit, Clinical Cardiology Division, Heart Institute (InCor, Medical School Hospital, University of São Paulo, São Paulo, Brazil Purpose: Acute myocardial infarction (MI is accompanied by myocardial inflammation, fibrosis, and ventricular remodeling that, when excessive or not properly regulated, may lead to heart failure. Previously, lipid core nanoparticles (LDE used as carriers of the anti-inflammatory drug methotrexate (MTX produced an 80-fold increase in the cell uptake of MTX. LDE-MTX treatment reduced vessel inflammation and atheromatous lesions induced in rabbits by cholesterol feeding. The aim of the study was to investigate the effects of LDE-MTX on rats with MI, compared with commercial MTX treatment.Materials and methods: Thirty-eight Wistar rats underwent left coronary artery ligation and were treated with LDE-MTX, or with MTX (1 mg/kg intraperitoneally, once/week, starting 24 hours after surgery or with LDE without drug (MI-controls. A sham-surgery group (n=12 was also included. Echocardiography was performed 24 hours and 6 weeks after surgery. The animals were euthanized and their hearts were analyzed for morphometry, protein expression, and confocal microscopy.Results: LDE-MTX treatment achieved a 40% improvement in left ventricular (LV systolic function and reduced cardiac dilation and LV mass, as shown by echocardiography. LDE-MTX reduced the infarction size, myocyte hypertrophy and necrosis, number of inflammatory cells, and myocardial fibrosis, as shown by morphometric analysis. LDE-MTX increased antioxidant enzymes; decreased apoptosis, macrophages, reactive oxygen species production; and tissue hypoxia in non-infarcted myocardium. LDE-MTX increased adenosine

Childhood depression: a systematic review

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Lima NNR

2013-09-01

Full Text Available Nádia Nara Rolim Lima,1 Vânia Barbosa do Nascimento,1 Sionara Melo Figueiredo de Carvalho,1 Luiz Carlos de Abreu,1,3 Modesto Leite Rolim Neto,2 Aline Quental Brasil,2 Francisco Telésforo Celestino Junior,2 Gislene Farias de Oliveira,2 Alberto Olavo Advíncula Reis3 1Programa de Pós-graduação em Ciências da Saúde, Faculdade de Medicina do ABC, Santo André, São Paulo, Brazil; 2Departamento de Medicina. Universidade Federal do Ceará, UFC, Barbalha, Ceará, Brazil; 3Departamento de Saúde Materno Infantil, Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, Brazil Abstract: As an important public health issue, childhood depression deserves special attention, considering the serious and lasting consequences of the disease to child development. Taking this into consideration, the present study was based on the following question: what practical contributions to clinicians and researchers does the current literature on childhood depression have to offer? The objective of the present study was to conduct a systematic review of articles regarding childhood depression. To accomplish this purpose, a systematic review of articles on childhood depression, published from January 1, 2010 to November 24, 2012, on MEDLINE and SciELO databases was carried out. Search terms were “depression” (medical subject headings [MeSH], “child” (MeSH, and "childhood depression" (keyword. Of the 180 retrieved studies, 25 met the eligibility criteria. Retrieved studies covered a wide range of aspects regarding childhood depression, such as diagnosis, treatment, prevention and prognosis. Recent scientific literature regarding childhood depression converge to, directly or indirectly, highlight the negative impacts of depressive disorders to the children's quality of life. Unfortunately, the retrieved studies show that childhood depression commonly grows in a background of vulnerability and poverty, where individual and familiar needs

Science.gov (United States)

Gómez, Luis Alberto; Montoya, Gladis; Rivera, Hernán Mauricio; Hernández, Juan Carlos

2017-04-01

Introducción. El virus del Zika (ZIKV) es un flavivirus con envoltura, transmitido a los seres humanos principalmente por el vector Aedes aegypti. La infección por ZIKV se ha asociado con un gran neurotropismo y con efectos neuropáticos, como el síndrome de Guillain-Barré en el adulto y la microcefalia fetal y posnatal, así como con un síndrome de infección congénita similar al producido por el virus de la rubéola (RV).Objetivo. Comparar las estructuras moleculares de la proteína de envoltura E del virus del Zika (E-ZIKV) y de la E1 del virus de la rubéola (E1-RV), y plantear posibles implicaciones en el neurotropismo y en las alteraciones del sistema nervioso asociadas con el ZIKV.Materiales y métodos. La secuencia de aminoácidos de la proteína E-ZIKV (PDB: 5iZ7) se alineó con la de la glucopreteína E1 del virus de la rubéola (PDB: 4ADG). Los elementos de la estructura secundaria se determinaron usando los programas Vector NTI Advance®, DSSP y POSA, así como herramientas de gestión de datos (AlignX®). Uno de los criterios principales de comparación y alineación fue la asignación de residuos estructuralmente equivalentes, con más de 70 % de identidad.Resultados. La organización estructural de la proteína E-ZIKV (PDB: 5iZ7) fue similar a la de E1-RV (PDB: 4ADG) (70 a 80 % de identidad), y se observó una correspondencia con la estructura definida para las glucoproteínas de fusión de membrana de clase II de los virus con envoltura. E-ZIKV y E1-RV exhibieron elementos estructurales de fusión muy conservados en la región distal del dominio II, asociados con la unión a los receptores celulares de entrada del virus de la rubéola (glucoproteína de mielina del oligodendrocito, Myelin Oligodendrocyte Glycoprotein, MOG), y con los receptores celulares Axl del ZIKV y de otros flavivirus.Conclusión. La comparación de las proteínas E-ZIKV y E1-RV es un paso necesario hacia la definición de otros factores moleculares determinantes del

Application of Electron Accelerators in Conjunction with Microwave Sources in Medical Studies

International Nuclear Information System (INIS)

Martin, D.; Craciun, G.; Manaila, E.; Ighigeanu, D.; Margaritescu, I.; Chirita, D.; Neagu, M.

2009-01-01

Electron beams (EB) are presently used, in addition to the routine conventional radiotherapy techniques, for cancer specialized therapies (intensity modulated radiation therapy [1] and total body electron irradiation [2]), the irradiation of blood and blood components, vaccine preparation, and other. Microwaves (MW) are presently used for therapeutic applications in cardiology, urology, surgery, ophthalmology, cancer therapy, and others, and for diagnostic applications such as cancer detection, organ imaging, and more [3]. The reported data show that low dose-all body irradiation with ionizing as well as with nonionizing irradiation may enhance the tumoricidal effects of radiation or chemotherapy, overcome acquired drug resistance and can stimulate certain components of the immune system that may aid in destroying cancer cells. These data suggested that application of low-dose total body EB + MW irradiation in conjunction with chemotherapy could contribute by novel effects to the cancer therapies. In view of this argument two specifically designed radiation exposure devices (REDs) were carried out for separate, successive and simultaneous irradiation with EB of 6.23 MeV and MW of 2.45 GHz in vivo (RED-vivo) and in vitro (RED-vitro) for the following medical studies: 1) The effects of low-dose EB + MW total body irradiation without/with drugs administration on the C57 BL/6 mice bearing malignant melanoma (MM); 2) The effects of separate and simultaneous MW and EB irradiation on MM cells culture without/with drugs incubation and on human blood components (proteins and cells) irradiated in samples of integral blood from healthy donors and from donors with MM. Both REDs consist of the following units: 1) An accelerated EB source: ALIN-10 electron linear accelerator of 6.23 MeV and adjustable absorbed dose rate from 0.002 Gy s-1 up to 70 Gy s-1 (built in the NILPRP, Bucharest, Romania); 2) A special designed exposure chamber that permits inside separate, successive or

Influence of FTO rs9939609 polymorphism on appetite, ghrelin, leptin, IL6, TNFα levels, and food intake of women with morbid obesity

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Magno FCCM

2018-05-01

Full Text Available Fernanda Cristina Carvalho Mattos Magno,1 Helena Chrispim Guaraná,1 Ana Carolina Proença Fonseca,2 Giselda Maria Kalil Cabello,2 João Régis Ivar Carneiro,3 Aline Pereira Pedrosa,1 Ana Carolina Ximenes,1 Eliane Lopes Rosado1 1Institute of Nutrition, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil; 2Oswaldo Cruz Foundation (FIOCRUZ, Oswaldo Cruz Institute (IOC, Human Genetics Laboratory, Rio de Janeiro, RJ, Brazil; 3Federal University of Rio de Janeiro, University Hospital Clementino Fraga Filho, Service of Nutrology, Rio de Janeiro, RJ, Brazil Background: The fat mass and obesity-related (FTO gene has a strong relationship with obesity, extreme obesity and inflammatory state, and may also be associated with food intake regulation.Objective: The aim of the present study was to evaluate the influence of the rs9939609 single-nucleotide polymorphism of the FTO gene on appetite, ghrelin, leptin, interleukin 6 (IL6, tumor necrosis factor α (TNFα levels and food intake of morbidly obese women.Materials and methods: The study comprised 70 women, aged between 20 and 48 years, from Rio de Janeiro, Brazil. The participants were selected according to the body mass index between 40 and 60 kg/m2. Anthropometric and biochemical data were measured during fasting. Hormones and inflammatory data were measured before and after the participants ate an isocaloric meal. Dietary records were calculated and analyzed using a nutritional assessment program. Visual analog scales were used for behaviors of the sensations of appetite and food preferences. The FTO rs9939609 variant was genotyped using real-time polymerase chain reaction.Results: Participants with the AA genotype had lower values of ghrelin and IL6 and higher values of leptin than those with TT and TA in the postprandial period. Comparing the plasma concentrations of ghrelin, insulin, IL6 and TNFα intragenotypes, it was observed that those with TT had decreased leptin and increased IL6

Does partner selection mediate the relationship between school attendance and HIV/HSV-2 among adolescent girls and young women in South Africa: An analysis of HPTN 068 data.

Science.gov (United States)

Stoner, Marie Cd; Edwards, Jessie K; Miller, William C; Aiello, Allison E; Halpern, Carolyn T; Julien, Aimée; Rucinski, Katherine B; Selin, Amanda; Twine, Rhian; Hughes, James P; Wang, Jing; Agyei, Yaw; Gómez-Olivé, F Xavier; Wagner, Ryan G; Laeyendecker, Oliver; Macphail, Catherine; Kahn, Kathleen; Pettifor, Audrey

2018-05-22

Similar prior publications by the first author using the same data source include: Stoner M.C.D, Edwards J, Miller W, Aiello A, Halpern C, Selin A, Hughes J, Wang J, Laeyendecker O, Agyei Y, McPhail C, Kahn K, Pettifor A.(2017) The effect of schooling on incident HIV and HSV-2 infection in young South African women enrolled in HPTN 068. AIDS. 24;31(15):2127-213. PMC5599334. Stoner M.C.D, Edwards J, Miller W, Aiello A, Halpern C, Julien Suarez, Selin A, Hughes J, Wang J, McPhail C, Kahn K, Pettifor A. (2017) The effect of schooling on age-disparate relationships and number of sexual partners among young women in rural South Africa enrolled in HPTN 068. J Acquir Immune Defic Syndr. 76 (5):e107-e114. PMC56801112This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal.Abstract OBJECTIVE:: School attendance prevents HIV and HSV-2 in adolescent girls and young women (AGYW) but the mechanisms to explain this relationship remain unclear. Our study assesses the extent to which characteristics of sex partners, partner age and number, mediate the relationship between attendance and risk of infection in AGYW in South Africa. We use longitudinal data from the HPTN 068 randomized controlled trial in rural South Africa where girls were enrolled in early adolescence and followed in the main trial for over three years. We examined older partners and number of partners as possible mediators. We use the parametric g-formula to estimate 4-year risk differences for the effect of school attendance on cumulative incidence of HIV/HSV-2 overall and the controlled direct effect (CDE) for mediation. We examined mediation separately and jointly for the mediators of interest. We found that young women with high attendance in school had

Le Bestiaire d'amour de Gustave Flaubert (1

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Loïc Windels

2010-09-01

Full Text Available « Désirer, c'est tuer ». Voilà ce qu’un Ministère de la Prévention fera bientôt imprimer sur le bandeau accompagnant les ventes du second des Trois contes. Du reste, il est certain que sa carte du Tendre empiète quelque peu sur les géographies du Cruel. Qui se penche sur son bestiaire en relève généralement assez vite le caractère symbolique et la couleur pré-freudienne. Flaubert ferait, avec le légendaire médiéval, ce que Freud peu après avec la mythologie grecque. Ces remarques et quelques autres ont parfois été faites1, et nul doute qu'elles ne soient familières à l'amateur de cette prose dense et suggestive qu'est La Légende de Saint Julien L'Hospitalier. Aussi le présent article (comme celui qui le suivra voudrait-il moins rouvrir à nouveaux frais un débat déjà bien nourri que l'aborder de façon quelque peu différente : en choisissant, parmi les épisodes où les animaux tiennent un rôle prépondérant, ceux qui semblent s'apparier pour former – à sauts et à gambades – un récit sous l'histoire, et ceux qui, en même temps, paraissaient désirer qu'on les confronte à d'autres textes (reste de l'œuvre, bestiaires médiévaux, histoires naturelles anciennes et modernes, mythographies et à quelques images.In The Legend of Saint Julian the Hospitalier – the middle of Flaubert’s Three Tales – to desire and to kill are but one thing, and its Map of Tendre encroaches somewhat on the topographies of Cruelty. He who looks into his bestiary is usually rather quick to detect its symbolic character and pre-Freudian overtones. It is as if Flaubert did with Medieval legends what Freud would do a little later with Greek mythology. These observations and other similar ones have already been made, and there is no doubt that the reader who loves the dense and suggestive prose that is The Legend of Saint Julian is familiar with them. Thus, the present article (and the one that will follow strive less to

Randomized clinical trial comparing manual suture and different models of mechanical suture in the mimicking of bariatric surgery in swine

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Fernandes MA

2014-02-01

Full Text Available Marcos AP Fernandes,1 Bruno MT Pereira,2 Sandra M Guimarães,1 Aline Paganelli,3 Carlos Manoel CT Pereira,1 Claudio Sergio Batista4 1Institute of Obesity and Advanced Video Laparoscopic Surgery of Petropolis, Rio de Janeiro, Brazil; 2Division of Trauma, University of Campinas, São Paulo, Brazil; 3Laboratório de Patologia Micron Cell Diagnóstico, Rio de Janeiro, Brazil; 4Department of Gynecology and Obstetrics, Faculty of Medicine of Petropolis, Rio de Janeiro, Brazil Context and objective: Variations in the ability of surgeons served as motivation for the development of devices that, overcoming individual differences, allow the techniques to be properly performed, and of which the end result was the best possible. Every technique must be reproduced reliably by the majority of surgeons for their results to be adopted and recognized as effective. The aim of this study was to compare the results, from the point of view of anatomic pathology, of manual sutures versus mechanical sutures using different models of linear mechanical staplers, in the procedure of gastroenteroanastomosis and enteroanastomosis in swine. Methods: Thirty-six healthy, adult, male Sus scrofa domesticus pigs, weighing between 20.7 and 25.5 kg, were used. The swine were randomly divided into four groups of nine pigs, according to the type of suture employed: group A, manual suture with Polysorb® 3-0 wire; group B, 80-shear linear stapler (Covidien® Gia 8038-S; group C, 75-shear linear stapler (Ethicon® Tlc 75; and group D, 75-shear linear stapler (Resource® Yq 75-3. A temporal study was established on the seventh postoperative day for histopathological analysis, and the degree of inflammation, fibrosis, and newly formed vessels, as well as the presence or absence of granulation tissue, foreign body granuloma, and necrosis were all evaluated qualitatively and semiquantitatively. The results were analyzed statistically. Results: Observations during the histopathological

Relationship between linear and nonlinear dynamics of heart rate and impairment of lung function in COPD patients

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Mazzuco A

2015-08-01

Full Text Available Adriana Mazzuco,1 Wladimir Musetti Medeiros,2 Milena Pelosi Rizk Sperling,1 Aline Soares de Souza,2 Maria Clara Noman Alencar,2 Flávio Ferlin Arbex,2 José Alberto Neder,2,3 Ross Arena,4 Audrey Borghi-Silva1 1Cardiopulmonary Physiotherapy Laboratory, Federal University of São Carlos, São Carlos, 2Pulmonary Function and Clinical Exercise Physiology Unit, Respiratory Division, Department of Medicine, Federal University of São Paulo, São Paulo, Brazil; 3Laboratory of Clinical Exercise Physiology, Division of Respiratory and Critical Care Medicine, Department of Medicine, Queen’s University, Kingston, ON, Canada; 4Department of Physical Therapy and Integrative Physiology Laboratory, College of Applied Health Sciences, University of Illinois Chicago, Chicago, IL, USA Background: In chronic obstructive pulmonary disease (COPD, functional and structural impairment of lung function can negatively impact heart rate variability (HRV; however, it is unknown if static lung volumes and lung diffusion capacity negatively impacts HRV responses. We investigated whether impairment of static lung volumes and lung diffusion capacity could be related to HRV indices in patients with moderate to severe COPD. Methods: Sixteen sedentary males with COPD were enrolled in this study. Resting blood gases, static lung volumes, and lung diffusion capacity for carbon monoxide (DLCO were measured. The RR interval (RRi was registered in the supine, standing, and seated positions (10 minutes each and during 4 minutes of a respiratory sinus arrhythmia maneuver (M-RSA. Delta changes (Δsupine-standing and Δsupine-M-RSA of the standard deviation of normal RRi, low frequency (LF, normalized units [nu] and high frequency (HF [nu], SD1, SD2, alpha1, alpha2, and approximate entropy (ApEn indices were calculated. Results: HF, LF, SD1, SD2, and alpha1 deltas significantly correlated with forced expiratory volume in 1 second, DLCO, airway resistance, residual volume, inspiratory

In vivo and in vitro evaluation of octyl methoxycinnamate liposomes

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de Carvalho Varjão Mota A

2013-12-01

Full Text Available Aline de Carvalho Varjão Mota,1 Zaida Maria Faria de Freitas,1 Eduardo Ricci Júnior,1 Gisela Maria Dellamora-Ortiz,1 Ralph Santos-Oliveira,2 Rafael Antonio Ozzetti,3 André Luiz Vergnanini,3 Vanessa Lira Ribeiro,4 Ronald Santos Silva,4 Elisabete Pereira dos Santos11Faculty of Pharmacy, Federal University of Rio de Janeiro, 2Nuclear Engineering Institute, National Nuclear Energy Commission, 3Allergisa Dermatocosmetic Research, University of Campinas, São Paulo, 4Pharmacology and Toxicology Department, National Insitute of Quality Control in Health, Oswaldo Cruz Foundation, Rio de Janeiro, BrazilAbstract: Solar radiation causes damage to human skin, and photoprotection is the main way to prevent these harmful effects. The development of sunscreen formulations containing nanosystems is of great interest in the pharmaceutical and cosmetic industries because of the many potential benefits. This study aimed to develop and evaluate an octyl methoxycinnamate (OMC liposomal nanosystem (liposome/OMC to obtain a sunscreen formulation with improved safety and efficacy by retaining OMC for longer on the stratum corneum.Methods: The liposome/OMC nanostructure obtained was tested for enzymatic hydrolysis with lipase from Rhizomucor miehei and biodistribution with liposomes labeled with technetium-99m. The liposome/OMC formulation was then incorporated in a gel formulation and tested for ocular irritation using the hen’s egg test-chorio-allantoic membrane (HET-CAM assay, in vitro and in vivo sun protection factor, in vitro release profile, skin biometrics, and in vivo tape stripping.Results: The liposome/OMC nanosystem was not hydrolyzed from R. miehei by lipase. In the biodistribution assay, the liposome/OMC formulation labeled with technetium-99m had mainly deposited in the skin, while for OMC the main organ was the liver, showing that the liposome had higher affinity for the skin than OMC. The liposome/OMC formulation was classified as nonirritating in

Hypoglycemia hospitalization frequency in patients with type 2 diabetes mellitus: a comparison of dipeptidyl peptidase 4 inhibitors and insulin secretagogues using the French health insurance database

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Detournay B

2015-07-01

Full Text Available Bruno Detournay,1 Serge Halimi,2,3 Julien Robert,1 Céline Deschaseaux,4 Sylvie Dejager5,6 1Cemka-Eval, Bourg-la Reine, France; 2Department of Diabetology, Endocrinology and Nutrition, Grenoble University Hospital Center, Grenoble, France; 3University Joseph Fourier, Grenoble, France; 4Novartis Pharma SAS, Market Access Department, Rueil-Malmaison, France; 5Novartis Pharma SAS, Medical and Scientific Affairs, Rueil Malmaison, France; 6Department of Diabetology, Metabolism and Endocrinology, Pitié-Salpétrière Hospital, Paris, France Aim: We aimed to compare the frequency of severe hypoglycemia leading to hospitalization (HH and emergency visits (EV for any cause in patients with type 2 diabetes mellitus exposed to dipeptidyl peptidase 4 (DPP4 inhibitors (DPP4-i versus those exposed to insulin secretagogues (IS; sulfonylureas or glinides. Methods: Data were extracted from the EGB (Echantillon Généraliste des Bénéficiaires database, comprising a representative sample of ~1% of patients registered in the French National Health Insurance System (~600,000 patients. Type 2 diabetes mellitus patients exposed to regimens containing either a DPP4-i (excluding treatment with IS, insulin, or glucagon-like peptide 1 analog or IS (excluding treatment with insulin and any incretin therapy between 2009 and 2012 were selected. HH and EV during the exposure periods were identified in both cohorts. A similar analysis was conducted considering vildagliptin alone versus IS. Comparative analyses adjusting for covariates within the model (subjects matched for key characteristics and using multinomial regression models were performed. Results: Overall, 7,152 patients exposed to any DPP4-i and 1,440 patients exposed to vildagliptin were compared to 10,019 patients exposed to IS. Eight patients (0.11% from the DPP4-i cohort and none from the vildagliptin cohort (0.0% were hospitalized for hypoglycemia versus 130 patients (1.30% from the IS cohort (138

INFRACŢIUNILE PREVĂZUTE LA ART.164 ŞI 166 CP RM: ASPECTE TEORETICE ŞI PRACTICE

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Sergiu BRÎNZA

2015-11-01

Full Text Available Analiza efectuată în cadrul acestui articol are ca obiect caracteristicile juridico-penale ale infracţiunilor specificate la art.164 şi 166 CP RM. Se argumentează că, în cazul infracţiunii specificate la art.164 CP RM, constrângerea fizică se poate concretiza în: 1 vătămarea intenţionată gravă, medie sau uşoară a integrităţii corporale ori a sănătăţii; 2 violenţa care nu implică un prejudiciu cauzat sănătăţii. În continuare, se arată că oricare din tipurile de arme menţionate în Legea privind regimul armelor şi al muniţiilor cu destinaţie civilă pot fi aplicate ca mijloace de săvârşire a infracţiunii prevă-zute la lit.g alin.(2 art.164 CP RM. Or, legiuitorul nu a stabilit nicio limitare a tipurilor de arme ce pot fi aplicate la răpirea unei persoane. Contează doar ca armele să fie utilizabile în vederea anihilării unei persoane. Nu în ultimul rând, în legătură cu infracţiunile prevăzute la art.166 CP RM, se relevă că, în condiţiile Republicii Moldova, care se confruntă cu fenomenul separatismului, restrângerea libertăţii persoanei are un caracter ilegal şi atunci când este exercitată de autorităţile neconstituţionale care controlează partea de est a ţării.THE OFFENCES REFERRED TO AT ART.164. AND 166 PC RM: THEORETICAL AND PRACTICAL ASPECTS The analysis performed in this article covers the legal-penal characteristics of the offences specified in art.164 and 166 PC RM. It is argued that, with regard to the offence specified in art.164 PC RM, the physical constraint may result in: 1 intentional grave, ordinary or easy battery or health harm; 2 violence without any health harm. Further, it is shown that any of the types of weapons mentioned in Law on weapons and ammunition destined for civil usage can be applied as means of committing the offence referred to at lett.g par.(2 art.164 PC RM. Or, the legislature did not set any limitation on the types of weapons that can be

Bookreviews

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Redactie KITLV

2009-07-01

Full Text Available Afro-Atlantic Dialogues: Anthropology in the Diaspora, edited by Kevin A. Yelvington (reviewed by Aisha Khan Central Africans, Atlantic Creoles, and the Foundation of the Americas, 1585-1660, by Linda M. Heywood & John K. Thornton (reviewed by James H. Sweet An Eye for the Tropics: Tourism, Photography, and Framing the Caribbean Picturesque, by Krista A. Thompson (reviewed by Carl Thompson Taíno Indian Myth and Practice: The Arrival of the Stranger King, by William F. Keegan (reviewed by Frederick H. Smith Historic Cities of the Americas: An Illustrated Encyclopedia, by David F. Marley (reviewed by Richard L. Kagan Arming Slaves: From Classical Times to the Modern Age, edited by Christopher Leslie Brown & Philip D. Morgan (reviewed by James Sidbury Sweet Negotiations: Sugar, Slavery, and Plantation Agriculture in Early Barbados, by Russell R. Menard (reviewed by Kenneth Morgan Jamaica in 1850 or, The Effects of Sixteen Years of Freedom on a Slave Colony, by John Bigelow (reviewed by Jean Besson Moral Capital: Foundations of British Abolitionism, by Christopher Leslie Brown (reviewed by Cassandra Pybus Caribbean Journeys: An Ethnography of Migration and Home in Three Family Networks, by Karen Fog Olwig (reviewed by George Gmelch Afro-Caribbean Immigrants and the Politics of Incorporation: Ethnicity, Exception, or Exit, by Reuel R. Rogers (reviewed by Kevin Birth Puerto Rican Arrival in New York: Narratives of the Migration, 1920-1950, edited by Juan Flores (reviewed by Wilson A. Valentín-Escobar The Conquest of History: Spanish Colonialism and National Histories in the Nineteenth Century, by Christopher Schmidt-Nowara (reviewed by Aline Helg Gender and Slave Emancipation in the Atlantic World, edited by Pamela Scully & Diana Paton (reviewed by Bernard Moitt Gender and Democracy in Cuba, by Ilja A. Luciak (reviewed by Florence E. Babb The “New Man” in Cuba: Culture and Identity in the

Validity of COPD diagnoses reported through nationwide health insurance systems in the People’s Republic of China

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Kurmi OP

2016-03-01

Full Text Available Om P Kurmi,1 Julien Vaucher,1 Dan Xiao,2 Michael V Holmes,1 Yu Guo,3 Kourtney J Davis,4 Chen Wang,5 Haiyan Qin,6 Iain Turnbull,1 Peng Peng,7 Zheng Bian,3 Robert Clarke,1 Liming Li,8 Yiping Chen,1 Zhengming Chen1 On behalf of the China Kadoorie Biobank collaborative group 1Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU, Nuffield Department of Population Health, University of Oxford, Oxford, UK; 2Tobacco Medicine and Tobacco Cessation Center, China–Japan Friendship Hospital, Beijing, People’s Republic of China; 3National Coordinating Centre for China Kadoorie Biobank Study, Chinese Academy of Medical Sciences, Beijing, People’s Republic of China; 4Worldwide Epidemiology, GlaxoSmithKline R&D, Collegeville, PA, USA; 5National Clinical Research Center for Respiratory Diseases, China-Japan Friendship Hospital, Beijing, People’s Republic of China; 6Medical Research Center, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China; 7Radiology Department, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China; 8Department of Epidemiology, School of Public Health, Peking University Health Science Center, Beijing, People’s Republic of China Background: COPD is the fourth leading cause of death worldwide, with particularly high rates in the People’s Republic of China, even among never smokers. Large population-based cohort studies should allow for reliable assessment of the determinants of diseases, which is dependent on the quality of disease diagnoses. We assessed the validity of COPD diagnoses collected through electronic health records in the People’s Republic of China. Methods: The CKB study recruited 0.5 million adults aged 30–79 years from ten diverse regions in the People’s Republic of China during the period 2004–2008. During 7 years of follow-up, 11,800 COPD cases were identified by linkage with mortality registries and the national

PV-HYBRID and MINI-GRID. Proceedings

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-07-01

design and validation of PV-hybrid sysem technology for rural electrification programmes in remote areas of Europe (Xavier Valive); (17) Analysis of inverter-controlled Island grids - transient simulations with ATP-EMTP and PowerFactory (Martin Braun); (18) Design of a PV-diesel hybrid energy system (William Lawrance); (19) Hybrid storage systems in PV stand alone applications impact on sizing and performance (Julien Labbe); (20) Sizing and analysis of a small hydro PV hybrid system for the rural electrification in developing countries (Joseph Kenfack); (21) Identification of dynamic equivalents for microgrids with high penetration of solar energy using ANNs (F.O. Resende); (22) Constructing village PV hybrid power systems on a wide-scale in Western China: Experience gained (Henrik Bindner); (23) Experiences with large-scale construction of PH hybrid village power systems in Western China (Winfried Klinghammer); (24) A detailed data based analysis of the behaviour of a 10+5+20 KW wind-PV-diesel hybrid sysem (Luis M. Arribas); (25) PV hybrid village electrification in French Guyana (Christian Dumbs); (26) Energy consumption patterns in village PV-diesel-hybrid systems (Javier Munoz); (27) From Subag to Ponelo hybrid photovoltaic-diesel system in Indonesia, lessons learned (Adjat Sudradjat); (28) PV diesel hybrid system in rural Africa - an inter-disciplinary approach (Markus Landau); (29) Making PV-diesel hybrids and PV or wind mini-grids sustainable in remote developing country sites: the Nabouwalu case (Philippe Veyan); (30) Mini-grid for an isolated island sandwip in Bangladesh (B.K. Bala).

A Concept for Providing Warning of Chelyabinsk-like Meteors, including those approaching from the Sun

Science.gov (United States)

Dunham, D. W.; Reitsema, H.; Lu, E.; Arentz, R.; Linfield, R.; Chapman, C. R.; Farquhar, R. W.; Furfaro, R.; Eismont, N. A.; Ledkov, A.; Chumachenko, E.

2013-12-01

's), including those in orbits mostly inside the Earth's orbit that are hard to find with Earth-based telescopes, from a Venus-like orbit. Few modifications would be needed to the 50cm aperture passively-cooled infrared-observing Sentinel Space Telescope to operate in a SE-L1 orbit, 0.01 AU from Earth towards the Sun, to find most asteroids larger than about 5 meters that approach the Earth from the solar direction. Many objects in the 25-50m range will not be found by current NEO surveys, while they would nearly always be seen by this possible mission. A dense metallic NEO as small as 5m across can rain destruction over an area of 1 or 2 square kilometers, as the Sikhote-Alin meteor showed in 1947 Other concepts are either ineffective at providing warning of asteroids approaching from the Sun, or are more expensive, involving three or more spacecraft. We should give better warning for future 'Bolts out of the blue'.

Évolution juridique et sociale de la cellule familiale dans l’Espagne franquiste (1938-1970, thèse de doctorat en histoire et civilisation espagnole en cotutelle entre l’Espagne et la France (Université de Cadix, direction Alberto Ramos Santana et Université de Nice, direction Marie-Aline Barrachina, Université de Cadix, 2011

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Florentina Rodrigo Paredes

2012-05-01

Full Text Available Cette thèse étudie la structure de la famille espagnole, et son évolution grâce à l’analyse des relations entre les normes législatives et la politique sociale entre 1938 et 1970. Pendant cette période, la famille subit d’importantes modifications dues aux principes et aux normes imposées par le franquisme. Parallèlement, l’État franquiste évolue sous la pression exercée par les forces sociales et du fait de la modernisation de la famille. Après la victoire des troupes franquistes en 1939, l’...

The dynamical interactions of Amazon deforestation, intensification of cattle ranching and technology adoption: insights from a socio-ecological model

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Müller-Hansen, Finn; Heitzig, Jobst; Donges, Jonathan F.; Cardoso, Manoel F.; Kurths, Jürgen; Thonicke, Kirsten

2017-04-01

. While most agent-based models in land science are developed for small study regions, our approach is scalable also to regional levels and for this purpose abstracts from many local specificities. In the proposed model, a collection of cattle ranchers interacts with the local environment via decisions to convert forest into pasture land and manage this pasture. Deforestation and land abandonment is traced by simple land-cover succession equations and ecological dynamics consider the evolution of pasture productivity depending on pasture management, deforestation and tree regrowth. Agent decisions are captured by heuristic strategies depending on economic and ecological constraints. Agents can follow either an extensive strategy, corresponding to traditional cattle ranching with fallow periods and slash-and-burn fertilization, or an intensive strategy, i.e. cattle ranching with high inputs such as machinery and industrial fertilizers. The choice of the production strategy is modeled as a social learning process: Agents are located on a geometric network representing neighborhood and acquaintance relations and imitate the successful strategies of their neighbors. We will present a comprehensive analysis of the model and discuss conditions that foster sustainable land use. Finally, we will give an outlook at possible extensions of the model and applications to issues such as compliance with Brazil's Forest Code and feedbacks from changes in climate. References: [1] Kaimowitz, David and Arild Angelsen (2008). "Will Livestock Intensification Help Save Latin America's Tropical Forests?" In: Journal of Sustainable Forestry 27.1-2, pp. 6-24. [2] Cohn, Avery S, Aline Mosnier, Petr Havlík, Hugo Valin, Mario Herrero, Erwin Schmid, Michael O'Hare, and Michael Obersteiner (2014). "Cattle ranching intensification in Brazil can reduce global greenhouse gas emissions by sparing land from deforestation." In: Proceedings of the National Academy of Sciences of the United States of America

PREFACE: International Conference on Strongly Correlated Electron Systems 2014 (SCES2014)

Science.gov (United States)

2015-03-01

The 2014 International Conference on Strongly Correlated Electron Systems (SCES) was held in Grenoble from the 7th to 11th of July on the campus of the University of Grenoble. It was a great privilege to have the conference in Grenoble after the series of meetings in Sendai (1992), San Diego (1993), Amsterdam (1994), Goa (1995), Zürich (1996), Paris (1998), Nagano (1999), Ann Arbor (2001), Krakow (2002), Karlsruhe (2004), Vienna (2005), Houston (2007), Buzios (2008), Santa Fe (2010), Cambridge (2011) and Tokyo (2013). Every three years, SCES joins the triennial conference on magnetism ICM. In 2015, ICM will take place in Barcelona. The meeting gathered an audience of 875 participants who actively interacted inside and outside of conference rooms. A large number of posters (530) was balanced with four parallel oral sessions which included 86 invited speakers and 141 short oral contributions. A useful arrangement was the possibility to put poster presentations on the website so participants could see them all through the conference week. Each morning two plenary sessions were held, ending on Friday with experimental and theoretical summaries delivered by Philipp Gegenwart (Augsburg) and Andrew Millis (Columbia). The plenary sessions were given by Gabriel Kotliar (Rutgers), Masashi Kawasaki (Tokyo), Jennifer Hoffman (Harvard), Mathias Vojta (Dresden), Ashvin Vishwanath (Berkeley), Andrea Cavalleri (Hamburg), Marc-Henri Julien (Grenoble), Neil Mathur (Cambridge), Giniyat Khaliullin (Stuttgart), and Toshiro Sakakibara (Tokyo). The parallel oral sessions were prepared by 40 symposium organizers selected by the chairman (Antoine Georges) and co-chairman (Kamran Behnia) of the Program Committee with the supplementary rule that speakers had not delivered an invited talk at the previous SCES conference held in 2013 in Tokyo. Special attention was given to help young researchers via grants to 40 overseas students. Perhaps due to the additional possibility of cheap

Predictive models and spatial analysis for the study of deserted medieval villages in Basilicata Region (Italy)

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Biscione, Marilisa; Danese, Maria; Masini, Nicola; Sabia, Canio

2016-04-01

(August 5, 2013); doi:10.1117/12.2027954 Danese M., Masini N., Biscione M., Lasaponara R. 2014. Predictive modeling for preventive Archaeology: Overview and case study. Central European Journal of Geosciences. March 2014,Volume 6, Issue 1, 42-55, doi: 10.2478/s13533-012-0160-5 G. Demians d'Archimbaud - Rougiers, Castrum médiéval déserté. In : Pays Sainte-Baume 9 (2001) 6-8 Lasaponara R., Masini N. 2009, Full-waveform Airborne Laser Scanning for the detection of medieval archaeological microtopographic relief, Journal of Cultural Heritage, 10S, pp. e78-e82, doi:10.1016/j.culher.2009.10.004. Lasaponara R., Leucci G., Masini N., Persico R., Scardozzi G., 2016, Towards an operative use of remote sensing for exploring the past using satellite data: The case study of Hierapolis (Turkey), Remote sensing of Environment, vol. 174: 148-164, doi:10.1016/j.rse.2015.12.016 Masini N. 1998, La fotointerpretazione aerea finalizzata allo studio morfologico dei siti urbani e fortificati medioevali della Basilicata, in "Castra ipsa possunt et debent reparari." Indagini conoscitive e metodologie di restauro delle strutture castellane normanno-sveve, a cura C. D. Fonseca, Roma, Edizioni De Luca, tomo I, pp. 205-250, ISBN: 8880162888 Podobnikar, T., Veljanovski, T., Stanèiè, Z., Oštir, K. (2001) Archaeological Predictive Modelling in Cultural Resource Management. In: Konečný, M. (ed): GI in EUROPE: integrative - interoperable - interactive. Proceedings of 4th Agile Conference on Geographic Information Science, April 19-21 2001, Brno, pp. 535-544.

PREFACE: 13th International Conference on Muon Spin Rotation, Relaxation and Resonance

Science.gov (United States)

2014-12-01

submitted 227 contributions, which were intensively discussed during day and evening sessions. The scientific program was centered around invited talks from speakers outside the μSR community, who presented lectures on topics where μSR is giving or expected to give significant contributions. The invited speakers, covering various fields of interest, included Radu Coldea (Oxford, Quantum Magnetism), Claude- Henri Delmas (Bordeaux, Electro- and Solid State Chemistry), Dirk Johrendt (Munich, Iron Based Materials), Marc-Henri Julien (Grenoble, Cuprate Superconductors), Manfred Fiebig (Zürich, Multiferroics), Allan MacDonald (Austin, Topological Electronic States), Hidenori Takagi (Stuttgart and Tokyo, Transition Metal Oxides), and Jean-Marc Triscone (Geneva, Oxide Heterostructures). In addition to an overview about status and progress of the existing facilities in Europe, Canada and Japan, future projects and new ideas for μSR facilities in South Korea, China and the USA were presented. A special evening session was held to discuss about muon site and muon states calculations by DFT and other techniques. Several talks and posters can be found on the conference web page www.psi.ch/muSR2014. In a ceremony at the beginning of the conference, Roberto De Renzi from the University of Parma was awarded the 2014 Yamazaki Prize for muon science by the International Society for Muon Spin Spectroscopy (ISMS) for his sustained and exceptional contributions to the development of the muon spin relaxation technique to investigate magnetism and superconductivity and for promoting synergies between μSR and NMR. In the closing session Rob Kie (UBC Vancouver and TRIUMF) very effectively summarized the five days of meeting, while giving an enlightening personal impression. In the same session five best poster prizes were awarded and ISMS gave two prizes to young researchers presenting outstanding work at the conference. The conference organizers also on behalf of the entire μSR community are

Modelling basin-wide variations in Amazon forest photosynthesis

Science.gov (United States)

Mercado, Lina; Lloyd, Jon; Domingues, Tomas; Fyllas, Nikolaos; Patino, Sandra; Dolman, Han; Sitch, Stephen

2010-05-01

type parameter values are assigned and assumed invariant with environmental condition but also ii) these models use leaf N as a factor that limit photosynthesis. Instead, since leaf P may also limit photosynthesis of the tropical forest (Reich et al. 2009), we use a more specific description of photosynthetic capacity across the basin based on the model evaluation done in Mercado et al. (2009) in which canopy photosynthetic capacity is related to foliar P but also using the relationships derived between canopy photosynthesis and leaf nutrients (N and P) from measurements in tropical trees (Domingues et al.In review). A study of this kind can inform the global vegetation/climate community as to the need for variability in key model parameters in order to accurately simulate carbon fluxes across the Amazon basin. Baker, T. R., et al. 2004. Increasing biomass in Amazonian forest plots. Philosophical Transactions of the Royal Society of London Series B-Biological Sciences 359 (1443):353-365. Phillips, O. L. et al. 2004. Pattern and process in Amazon tree turnover, 1976-2001. Philosophical Transactions of the Royal Society of London Series B-Biological Sciences 359 (1443):381-407. Malhi, Y. et al. 2004. The above-ground coarse wood productivity of 104 Neotropical forest plots. Global Change Biology 10 (5):563-591. Mercado, L.M. et al. 2009. Impact of changes in diffuse radiation on the global land carbon sink. Nature 458 (7241), 1014. Cox, P. M. et al. 1998. A canopy conductance and photosynthesis model for use in a GCM land surface scheme. Journal of Hydrology 213 (1-4):79-9 Sitch, S. et al. 2003. Evaluation of ecosystem dynamics, plant geography and terrestrial carbon cycling in the LPJ dynamic global vegetation model. Global Change Biology 9 (2):161-185. Reich B. R. et al. 2009. Leaf phosphorus influences the photosynhtesis-nitrogen relation: a cross-biome analysis of 314 species. Oecologia, doi 10.1007/s00442-009-1291-3. Domingues, T. et al. In review. Co-limitation of

Aproximación a la Animación Sociocultural desde una perspectiva didáctica

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Ana CALVO SASTRE

2009-11-01

of the Curriculum and its relationship with Socio-cultural Animation. Primarily, those theories that consider Curriculum development to be a process of investigation are analyzed, and, more specifically, those that express a critical vision of this. These theories constitute the conception of the Curriculum which best accommodates the idea of Socio-cultural Animation defended throughout the article.RÉSUMÉ: Le principal objectif de cet article est d'exposer quelques observations sur les processus d'Animation Socioculturelle dans une perspective didactique. Pour cela on analyse, d'une part, la relation entre l'Animation Socioculturelle comme pratique éducative et la Didactique comme discipline centrée sur l'étude des processus d'enseignement-apprentissage. Cette analyse est réalisée dans une perspective de complémentarité, la Didactique étant considérée comme un cadre de référence pour l'Animation Socioculturelle et l'Animation Socioculturelle étant considérée à son tour comme un domaine qui élargit les espaces d'action, de réflexion et de recherche de la Didactique. D'autre part, le dernier alinéa de l'article se centre plus spécifiquement sur la perspective du Curriculum et sa relation avec l'Animation Socioculturelle. Il analyse, surtout, les théories qui conçoivent la pratique du Curriculum comme processus de recherche et, plus particulièrement, les théories qui expriment une vision critique de ce dernier puisqu'elles offrent une conception du Curriculum qui permet à l'Animation Socioculturelle de s'adapter au mieux selon les observations réalisées sur ce concept tout au long de l'article.

Work team

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RBE Editorial

2016-06-01

, BrasilRaul Herrera Faúndez, Instituto de Biología Vegetal y Biotecnologia, Universidad de Talca, ChileWagner Seixas da Silva, Instituto de Bioquímica Médica, Universidade Federal do Rio de Janeiro (UFRJ, Brasil 2. Reviewers V14. N1, 2016Ana Lúcia Ana Lúcia Hoefel, Universidade Federal do Rio Grande do Sul (UFRGS, BrasilAndreza Costa Scatigno, Depto. Química, Universidade de Sorocaba UNISO, BrasilÁlvaro Reischack de Oliveira, Escola superior de Educação Física, Universidade Federal do Rio Grande do Sul (UFRGS, BrasilBayardo Bapstista Torres, Instituto de Química - USP, BrasilCarolina Nascimento Spiegel, Universidade Federal Fluminense, BrasilEduardo Galembeck, Depto. Bioquímica, Instituto de Biologia, UNICAMP, BrasilEduardo Fernandes Barbosa, Universidade Federal do Oeste da Bahia (UFOB, BrasilGabriel Gerber Hornink,Depto. Bioquímica, Instituto de Ciências Biomédicas, Universidade Federal de Alfenas (Unifal-MG, BrasilMaria Lucia Bianconi, Instituto de Bioquímica Médica Universidade Federal do Rio de Janeiro (UFRJ, BrasilMiguel Ángel Medina Torres, Department of Molecular Biology & Biochemistry Faculty of Sciences University of Málaga, SpainPâmela Billig Mello-Carpes, Universidade Federal do Pampa (Unipampa, BrasilPaulo Afonso Granjeiro, Universidade Federal de São João Del-Rei (UFSJ, BrasilVera Maria Treis Trindade, Depto. Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul (UFRGS, Brasil 3. Institutional support SBBq – Brasilian Society of Biochemistry and Molecular Biology: http://www.sbbq.org.brJerson Lima da Silva (UFRJ - Acting PresidentGlaucius Oliveira (IFSC - USP - Elected PresidentJosé Roberto Meyer Fernandes (UFRJ - Vice-PresidentWalter R. Terra (IQ-USP - General SecretarEduardo Moraes Rego Reis (IQ-USP - First SecretaryMaurício da Silva Baptista (IQ-USP - General treasurerAline Maria da Silva (IQ-USP - First treasurerAnibal Eugenio Vercesi (UNICAMP - National Policy Coordinator

CONSIDERAȚII TEORETICE ȘI PRACTICE PRIVIND INFRACȚIUNILE DE PRACTICARE ILEGALĂ A ACTIVITĂȚII DE ÎNTREPRINZĂTOR (art.241 DIN CODUL PENAL

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Vitalie STATI

2017-07-01

Full Text Available În prezentul studiu analizei sunt supuse temeiul real şi temeiul juridic ale răspunderii penale pentru faptele incriminate la art.241 CP RM. Sunt stabilite caracteristicile obiectului juridic şi ale obiectului imaterial în cazul infracţiunilor pre­văzute la art.241 CP RM. Se arată că noţiunea „activitate de întreprinzător”, utilizată în art.241 CP RM, are acelaşi înţeles ca şi noţiunea „activitate de întreprinzător” folosită în art.1 al Legii cu privire la antre­pre­no­riat şi întreprinderi. Se relevă forma şi conţinutul faptei prejudiciabile specificate la art.241 CP RM, prin prisma prevederilor de la lit.a-d art.125 CP RM. Se argumentează că calificarea desfăşurării activităţii de întreprinzător fără licenţă în baza art.241 CP RM (coroborat cu lit.b art.125 CP RM ar însemna nu altceva decât aplicarea prin analogie a legii penale, interzisă de alin.(2 art.3 CP RM. Sunt profilate particularităţile ce caracterizează consumarea infracţiunilor prevăzute la art.241 CP RM. Se stabileşte că scopul infracţiunilor prevăzute la art.241 CP RM este cel de asigurare a unei surse perma­nente de venituri. Sunt relevate ipotezele în care subiectul infracţiunilor prevăzute la art.241 CP RM are o calitate specială. Nu în ultimul rând, sunt elucidate criteriile de delimitare a infracţiunilor specificate la art.241 CP RM de infrac­ţiunile prevăzute la art.190, 2411, 244, 2441 şi altele din Codul penal.SOME THEORETICAL AND PRACTICAL CONSIDERATIONS WITH REGARD TO THE OFFENCE OF ILLEGAL PRACTICE OF ENTREPRENEURIAL ACTIVITY (art.241 OF THE PENAL CODEIn this study there are analyzed both the factual basis and the legal basis of the penal liability for the offences crimi­nalized in art.241 PCRM.There are also established the features of the legal object and the immaterial object of the offenses referred to at art.241 PCRM.It is argued that the concept of "entrepreneurial activity", applied in

Editorial

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Alberto Manuel Brandão Simões

2010-04-01

êmicos e da indústria que atuam nessas áreas.Os tópicos de interesse anunciados no Call for Papers estiveram centrados em torno dos trabalhos em tecnologia da linguagem humana em geral realizados a partir de perspectivas tão diversas como Ciências da Computação, Lingüística e Ciência da Informação, incluindo entre outros a mineração de texto, processamento da linguagem escrita e falada, a terminologia, lexicologia e lexicografia, modelagem e gestão de conhecimento e geração de linguagem natural. Foram submetidos 60 artigos longos e 26 curtos. Cada proposta foi analisada por três membros do Comitê de Programa, composto por 88 pesquisadores de 13 países e 45 instituições.Após um rigoroso processo de revisão 18 artigos completos e 12 curtos foram selecionados, com taxas de aceitação de 30% e 42%, respectivamente. Os autores dos artigos completos foram convidados a submeter versões estendidas e revisadas dos seus trabalhos para esta edição especial, passando por um novo processo de revisão, desta vez pelos revisores da Linguamática, que selecionaram 7 dos artigos submetidos.Estes artigos representam uma amostra do rico e variado trabalho apresentado no STIL e envolvem pesquisadores de instituições acadêmicas e industriais no Brasil, Portugal e França. Por exemplo, o primeiro artigo, Identificação de expressões multipalavra em domínios específicos de Aline Villavicencio et al., propõe uma abordagem para a identificação de Expressões Multipalavra, tais como compostos nominais e verbos frasais, em corpora técnicos. A proposta apresentada combina medidas de associação com informações linguísticas e de alinhamentos lexicais, e o artigo examina a influência de diversos fatores sobre o seu desempenho.Os dois próximos artigos são relacionados a aplicações de PLN. Em Classificação automática de textos por período literário utilizando compressão de dados através do PPM-C, Bruno Barufaldi et al. propõem a aplicação do m

PREFACE: Structure and dynamics determined by neutron and x-ray scattering Structure and dynamics determined by neutron and x-ray scattering

Science.gov (United States)

Müller-Buschbaum, Peter

2011-06-01

-resolved neutron backscattering Aline Léon and Joachim Wuttke Morphology of thin nanocomposite films of asymmetric diblock copolymer and magnetite nanoparticles Valeria Lauter, Peter Müller-Buschbaum, Hans Lauter and Winfried Petry Structural characterization of casein micelles: shape changes during film formation R Gebhardt, C Vendrely and U Kulozik

Microfacies characteristics, sedimentary environments and sequence stratigraphy of Upper Cretaceous deposits in northwest of Nehbandan (Basiran section

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Mohammad nabi Gorgij

2015-10-01

Full Text Available Introduction   The Basiran stratigraphic section is located about 160 km northwest of Nehbandan.The section was measured in detail at 59 06 30 N and 31 52 50 E. Nehbandan area with respect to fourfold geological subdivision of Iran is part of Central Iran that is located in the eastern flank of Lut Block which first time are studied by Stocklin et al.in 1972. Gorgij (2001 stratigraphically and paleontologically investigate Upper Cretaceous deposits in Mighan and Basiran sections. Upper Cretaceous deposits in in this area consists of 275m conglomerate,alternation of conglomerate-sandstone, sandy limestone -marl and limy marl, marl with intercalation of limestone-sandy limestone thin beds and medium-bedded to massive limestone. Microfacies analysis led to the recognition of 9 microfacies that are related to 5 belts; Coast, tidal flat, lagoon, shoal, shallow open marine and deep open marine environments. Main part of the section are deposited in the open marine environment that consist of marl,marly limestone and limestone. The doals of this study are : (1 describing and determining main carbonate and siliciclastic microfacies of late Cretaceous deposits (2 interpreting and providing depositional model for reconstruction of its paleoenvironmental setting based on microfacies characteristics (3 dividing the section based on lithostratigraphic principles and (4 recognizing a sequence stratigraphic model of this successions based on the vertical variation of facies,stratal key beds and stratal packing pattern.       Material and Method   The Basiran section as a complete stratigraphic section was measured and described. Up to 68 samples (indicated by KB1 to KB68 were collected and 170 thin sections are prepared. Based on field observations, sedimentological characteristics, parasequence stacking patterns, sequence boundary types and other key stratigraphical surfaces are identified and were obtained. Scheme of Dunham (1962 and Embry and Klovan

Microfacies characteristics, sedimentary environments and sequence stratigraphy of Upper Cretaceous deposits in northwest of Nehbandan (Basiran section

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Azadeh Bordbar

2015-09-01

Full Text Available   Introduction   The Basiran stratigraphic section is located about 160 km northwest of Nehbandan.The section was measured in detail at 59 06 30 N and 31 52 50 E. Nehbandan area with respect to fourfold geological subdivision of Iran is part of Central Iran that is located in the eastern flank of Lut Block which first time are studied by Stocklin et al.in 1972. Gorgij (2001 stratigraphically and paleontologically investigate Upper Cretaceous deposits in Mighan and Basiran sections. Upper Cretaceous deposits in in this area consists of 275m conglomerate,alternation of conglomerate-sandstone, sandy limestone -marl and limy marl, marl with intercalation of limestone-sandy limestone thin beds and medium-bedded to massive limestone. Microfacies analysis led to the recognition of 9 microfacies that are related to 5 belts Coast, tidal flat, lagoon, shoal, shallow open marine and deep open marine environments. Main part of the section are deposited in the open marine environment that consist of marl,marly limestone and limestone. The doals of this study are : (1 describing and determining main carbonate and siliciclastic microfacies of late Cretaceous deposits (2 interpreting and providing depositional model for reconstruction of its paleoenvironmental setting based on microfacies characteristics (3 dividing the section based on lithostratigraphic principles and (4 recognizing a sequence stratigraphic model of this successions based on the vertical variation of facies,stratal key beds and stratal packing pattern.       Material and Method   The Basiran section as a complete stratigraphic section was measured and described. Up to 68 samples (indicated by KB1 to KB68 were collected and 170 thin sections are prepared. Based on field observations, sedimentological characteristics, parasequence stacking patterns, sequence boundary types and other key stratigraphical surfaces are identified and were obtained. Scheme of Dunham (1962 and Embry

Apresentação da editora deste número 10.5007/1518-2924.2006v11nesp3pii

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Célia Regina Simonetti Barbalho

2006-12-01

Full Text Available No mundo de Babel em que vivemos não falamos uma mesma língua, mesmo quando nos expressamos através do mesmo idioma. Nesta obscura torre, onde o homem se manifesta pelas linguagens que constituiu, muitos são os modos como individualmente um sujeito compreende o que está implícito e explicito na teia de sentidos que foi cuidadosamente constituída e articulada para expressar significado. Dewey, ao constituir seu sistema de classificação, afirmou ser ele um construto para educação do individuo embora entendesse ser necessário “[...] saber como extrair sentido da página impressa”. De fato, independente do suporte onde se exibe, uma mensagem para se tornar um lance de comunicação, precisa ser assimilada, demandando que dela se extraia os sentidos que manifesta. Este desafio aproximou a Semiótica da Ciência da Informação uma vez que ambas buscam consolidar algo essencial para minimizar os impactos da obesidade de informação que se vivencia hoje, qual seja, promover acesso ao significado dos artefatos de cultura produzidos pelo homem de modo a fomentar saberes que constituam conhecimentos ou, como afirma Maria Aparecida Moura, no artigo Ciência da Informação e Semiótica: conexão de saberes, ambas procuram ampliar a compreensão das manifestações de modo a conectar conhecimento e sabedoria. Nesta perspectiva, a aproximação inicialmente ocorreu pelo foco que, aparentemente lhes é mais próximo, o das linguagens documentárias e suas semioses, como questiona Marilda Lopes Ginez de Lara, no artigo É possível falar em signo e semiose documentária? Assim exposta, tal aproximação da Semiótica com a Ciência da Informação ocorreu através das duas abordagens mais conhecidas da primeira: a corrente fenomenológica do americano Charles Sanders Peirce e a lingüística do lituano-francês Algirdas Julien Greimas, embora minimamente exista ainda a vertente russa da Escola de Tartu, representada por Iuri Lotman. Os estudos

Foreword

Science.gov (United States)

Aime, C.; Soummer, R.

very short explanation of how the reports are ordered is given here. The Journées of 2003 started with the delocalized lectures (delocalized means here “not in Paris”!) of the Collège de France, of Antoine Labeyrie who wrote a report on Removal of coronagraphy residues with an adaptive hologram. Three invited seminars follow: Olivier Guyon (Pupil remapping techniques), Daniel Rouan (Ultra-nulling interferometers), and Kjetil Dohlen (Phase masks in astronomy). An illustration from Daniel Rouan's talk on the properties of Prouhet-Thué-Morse series was also selected for the cover figure of this edition. These papers are followed by the courses and communications given during the 4 days of the school, in a slightly different order of their presentation. The first two days were on atmospheric turbulence and adaptive optics for coronagraphy, and also coronagraphic space projects. Steve Ridgway gives a general introduction to the problem (Astronomy with high contrast imaging). This is followed by a presentation on Fourier and Statistical Optics: Shaped and Apodized apertures (Claude Aime), The effect of a coronagraph on the statistics of adaptive optics pinned speckles (Claude Aime and Rémi Soummer). A general introduction to the problem of atmospheric turbulence is made by Julien Borgnino. A presentation of the Concordia site with emphasis on its advantages for high contrast imaging is given by Eric Fossat. Several presentations relative to numerical simulations of Adaptive Optics and coronagraphy follow: Marcel Carbillet (AO for very high contrast imaging), Lyu Abe and Anthony Boccaletti share two presentations on Numerical simulations for coronagraphy. These presentations are followed by reports on experiments: Sandrine Thomas (SAM-the SOAR adaptive module), Pierre Baudoz (Cryogenic IR test of the 4QPM coronagraph), Anthony Boccaletti (Coronagraphy with JWST in the thermal IR). Pierre Bourget (Hg-Mask Coronagraph) ends this part with a coronagraph using a mercury

Book Reviews

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Redactie KITLV

1995-01-01

: Development of Afro-Latin Religion among Puerto Ricans in the United States. A study into the Interpenetration of civilizations in the New World. New York: AMS Press, 1991. xvi + 273 pp. -Frank Jan van Dijk, Mihlawhdh Faristzaddi, Itations of Jamaica and I Rastafari (The Second Itation, the Revelation. Miami: Judah Anbesa Ihntahnah-shinahl, 1991. -Derwin S. Munroe, Nelson W. Keith ,The Social Origins of Democratic Socialism in Jamaica. Philadelphia: Temple University Press, 1992. xxiv + 320 pp., Novella Z. Keith (eds -Virginia Heyer Young, Errol Miller, Education for all: Caribbean Perspectives and Imperatives. Washington DC: Inter-American Development Bank, 1992. 267 pp. -Virginia R. Dominguez, Günter Böhm, Los sefardíes en los dominios holandeses de América del Sur y del Caribe, 1630-1750. Frankfurt: Vervuert, 1992. 243 pp. -Virginia R. Dominguez, Robert M. Levine, Tropical diaspora: The Jewish Experience in Cuba. Gainesville: University Press of Florida, 1993. xvii + 398 pp. -Aline Helg, John L. Offner, An unwanted war: The diplomacy of the United States and Spain over Cuba, 1895-1898. Chapel Hill: University of North Carolina Press, 1992. xii + 306 pp. -David J. Carroll, Eliana Cardoso ,Cuba after Communism. Cambridge MA: MIT Press, 1992. xiii + 148 pp., Ann Helwege (eds -Antoni Kapcia, Ian Isadore Smart, Nicolás Guillén: Popular Poet of the Caribbean. Columbia: University of Missouri Press, 1990. 187 pp. -Sue N. Greene, Moira Ferguson, The Hart Sisters: Early African Caribbean Writers, Evangelicals, and Radicals. Lincoln: University of Nebraska Press, 1993. xi + 214 pp. -Michael Craton, James A. Lewis, The final campaign of the American revolution: Rise and fall of the Spanish Bahamas. Columbia: University of South Carolina Press, 1991. xi + 149 pp. -David Geggus, Clarence J. Munford, The black ordeal of slavery and slave trading in the French West Indies, 1625-1715. Lewiston NY: The Edwin Mellen Press, 1991. 3 vols. xxii + 1054 pp. -Paul E. Sigmund, Timothy P

Book Reviews

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Redactie KITLV

1994-01-01

�rez Rolón, Vernon W. Boggs, Salsiology: Afro-Cuban music and the evolution of Salsa in New York City. New York: Greenwood, 1992. xvii + 387 pp. -Martin F. Murphy, Sherri Grasmuck ,Between two islands: Dominican international migration. Berkeley: University of California Press, 1991. xviii + 247 pp., Patricia R. Pessar (eds -Rosario Espinal, Richard S. Hillman ,Distant neighbors in the Caribbean: The Dominican Republic and Jamaica in comparative perspective. New York: Praeger, 1992. xviii + 199 pp., Thomas D'Agostino (eds -Svend E. Holsoe, Neville A.T. Hall, Slave society in the Danish West Indies: St. Thomas, St. John and St. Croix. Edited by B.W. Higman. Mona, Jamaica: University of the West Indies Press, 1992. xxiv + 287 pp. -Light Townsend Cummins, Francisco Morales Padrón, The journal of Don Francisco Saavedra de Sangronis 1780-1783. Translated by Aileen Moore Topping. Gainesville: University of Florida Press, 1989. xxxvii + 380 pp. -Francisco A. Scarano, Laird W. Bergad, Cuban rural society in the nineteenth century: The social and economic history of monoculture in Matanzas. Princeton: Princeton University Press, 1990. xxi + 425 pp. -Robert L. Paquette, Larry R. Jensen, Children of colonial despotism: Press, politics, and culture in Cuba, 1790-1840. Tampa: University of South Florida Press, 1988. xviii + 211 pp. -Robert L. Paquette, Anton L. Allahar, Class, politics, and sugar in colonial Cuba. Lewiston NY; The Edwin Mellen Press, 1990. xi + 217 pp. -Aline Helg, Josef Opatrny, U.S. Expansionism and Cuban annexationism in the 1850s. Prague: Charles University, 1990. 271 pp. -Rita Giacalone, Humberto García Muñiz ,Bibliografía militar del Caribe. Río Piedras PR: Centro de Investigaciones Históricas, Universidad de Puerto Rico, 1992. 177 pp., Betsaida Vélez Natal (eds -Carlos E. Santiago, Irma Tirado de Alonso, Trade issues in the Caribbean. Philadelphia: Gordon & Breach, 1992. xv + 231 pp. -Drexel G. Woodson, Frantz Pratt, Haiti: Guide to the periodical

Alternatives for the assessment of the solar resource in Argentina

International Nuclear Information System (INIS)

Grossi Gallegos, H; Righini, R; Raichijk, C

2005-01-01

geostatistical methods for interpolation, spatial distribution of this values were obtained for each month. Verifying with surfaces MBE of 3.8% and RMSE of 9.4% were obtained. Another alternative that is being analyzed is the estimation of solar irradiation with Tarpley model in five locations of Argentina employing GOES 8 images.The constants of the model were locally calculated using ground pyrano meters data; the model has shown RMSE between 13% and 24% for daily values.Finally, a method for estimating global solar irradiation proposed by Hargreaves et al.in 1985, based on differences between maximun and minimum temperatures, was evaluated in the same way, concluding that is a valid alternative giving uncertainties similar to those of more known models (MBE of -3.7% and RMSE of 11%).Therefore, authors consider that these methodologies constitute a valuable alternative for countries with a high number of stations for measuring solar sunshine hours and temperature, with sufficiently wide registers, and few stations for simultaneous measurement of global solar irradiation using pyrano meters

Book Reviews

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Redactie KITLV

1997-01-01

Full Text Available -Peter Hulme, Polly Pattullo, Last resorts: The cost of tourism in the Caribbean. London: Cassell/Latin America Bureau and Kingston: Ian Randle, 1996. xiii + 220 pp. -Michel-Rolph Trouillot, Édouard Glissant, Introduction à une poétique du Divers. Montréal: Presses de l'Université de Montréal, 1995. 106 pp. -Bruce King, Tejumola Olaniyan, Scars of conquest / Masks of resistance: The invention of cultural identities in African, African-American, and Caribbean drama. New York: Oxford University Press, 1995. xii + 196 pp. -Sidney W. Mintz, Raymond T. Smith, The Matrifocal family: Power, pluralism and politics. New York: Routledge, 1996. x + 236 pp. -Raymond T. Smith, Michel-Rolph Trouillot, Silencing the past: Power and the production of history. Boston: Beacon, 1995. xix + 191 pp. -Michiel Baud, Samuel Martínez, Peripheral migrants: Haitians and Dominican Republic sugar plantations. Knoxville: University of Tennessee Press, 1995. xxi + 228 pp. -Samuel Martínez, Michiel Baud, Peasants and Tobacco in the Dominican Republic, 1870-1930. Knoxville; University of Tennessee Press, 1995. x + 326 pp. -Robert C. Paquette, Aline Helg, Our rightful share: The Afro-Cuban struggle for equality, 1886-1912. Chapel Hill: University of North Carolina Press, 1995. xii + 361 pp. -Daniel C. Littlefield, Roderick A. McDonald, The economy and material culture of slaves: Goods and Chattels on the sugar plantations of Jamaica and Louisiana. Baton Rouge: Louisiana State University Press, 1993. xiv + 339 pp. -Jorge L. Chinea, Luis M. Díaz Soler, Puerto Rico: desde sus orígenes hasta el cese de la dominación española. Río Piedras: Editorial de la Universidad de Puerto Rico, 1994. xix + 758 pp. -David Buisseret, Edward E. Crain, Historic architecture in the Caribbean Islands. Gainesville: University Press of Florida, 1994. ix + 256 pp. -Hilary McD. Beckles, Mavis C. Campbell, Back to Africa. George Ross and the Maroons: From Nova Scotia to Sierra Leone. Trenton

Adaptation response surfaces from an ensemble of wheat projections under climate change in Europe

Science.gov (United States)

Ruiz-Ramos, Margarita; Ferrise, Roberto

2016-04-01

(14), Petr Hlavinka(7,8), Frantisek Jurecka(7,8), Jaromir Krzyszczak(10), Marcos Lana(6), Julien Minet(15), Manuel Montesino(16), Claas Nendel(6), John Porter(16), Jaime Recio(1), Françoise Ruget(11), Alberto Sanz(1), Zacharias Steinmetz(17,18), Pierre Stratonovitch(19), Iwan Supit(20), Domenico Ventrella(21), Allard de Wit(20) and Reimund P. Rötter(4). 1 Universidad Politecnica de Madrid, ETSIAgrónomos,28040 Madrid, Spain, margarita.ruiz.ramos@upm.es 2 University of Florence, 50144 Florence, Italy 3 IFAPA Junta de Andalucia, 14004 Córdoba, Spain 4 Natural Resources Institute (LUKE), 01370 Vantaa, Finland 5 Finnish Environment Institute (SYKE), 00250 Helsinki, Finland 6 Leibniz Centre for Agricultural Landscape Research (ZALF), 15374 Müncheberg, Germany 7 Institute of Agrosystems and Bioclimatology, Mendel University in Brno, Brno 613 00, Czech Republic 8 Global Change Research Institute CAS, 603 00 Brno, Czech Republic 9 INRES, University of Bonn, 53115 Bonn, Germany 10 Institute of Agrophysics Polish Academy of Sciences, Lublin, Poland 11 INRA, UMR 1114 EMMAH, F-84914 Avignon, France 12 James Hutton Institute, Invergowrie, Dundee, DD2 5DA, Scotland 13 State Key Laboratory of Earth Surface Processes and Resource Ecology, Academy of Disaster Reduction and Emergency Management, Beijing Normal University, Beijing 100875, China 14 University of Sassari, 07100 Sassari, Italy 15 Université de Liège, 4000 Liège, Belgium 16 University of Copenhagen, 2630 Taastrup, Denmark 17 RIFCON GmbH, 69493 Hirschberg, Germany 18 Group of Environmental and Soil Chemistry, Institute for Environmental Sciences, University of Koblenz-Landau, 76829 Landau, Germany 19 Rothamsted Research, Harpenden, Herts, AL5 2JQ, UK 20 Wageningen University, 6700AA Wageningen, The Netherlands 21 Consiglio per la ricerca in agricoltura e l'analisi dell'economia agraria. CRA-SCA

Phanerozoic continental growth and gold metallogeny of Asia

Science.gov (United States)

Goldfarb, Richard J.; Taylor, Ryan D.; Collins, Gregory S.; Goryachev, Nicolay A.; Orlandini, Omero Felipe

2014-01-01

associated with ca. 150–125 Ma formation of important auriferous epithermal (Balei), skarn (Bystray), and porphyry (Kultuminskoe) deposits. In northeastern Russia, Early Cretaceous Pacific margin subduction and Late Cretaceous extension were associated with epithermal gold-deposit formation in the Uda–Murgal (Julietta) and Okhotsk–Chukotka (Dukat, Kupol) volcanic belts, respectively. In southeastern Russia, latest Cretaceous to Oligocene extension correlates with other low-sulfidation epithermal ores that formed in the East Sikhote–Alin volcanic belt. Other extensional events, likely related to changing plate dynamics along the Pacific margin of Asia, relate to epithermal–skarn–porphyry districts that formed at ca. 125–85 Ma in northeastmost China and ca. 105–90 Ma in the Coast Volcanic belt of SE China. The onset of strike slip along a part of the southeastern Pacific margin appears to correlate with the giant 148–135 Ma gold-rich porphyry–skarn province of the lower and middle Yangtze River. It is still controversial as to whether true Carlin-like gold deposits exist in Asia. Those deposits that most closely resemble the Nevada (USA) ores are those in the Permo-Triassic Youjiang basin of SW China and NE Vietnam, and are probably Late Triassic in age, although this is not certain. Other Carlin-like deposits have been suggested to exist in the Sepon basin of Laos and in the Mongol–Okhotsk region (Kuranakh) of Transbaikal.

ESA's high-energy observatories spot doughnut-shaped cloud with a black-hole filling

Science.gov (United States)

2004-07-01

-energy X-rays seen by XMM-Newton appear to come from a diffuse emission, far away from the black hole, the higher-energy X-rays detected by Integral are directly related to the black hole activity. The team could infer the doughnut’s structure and its distance from the black hole by virtue of light that was either reflected or completely absorbed. The torus itself appears to be several hundred light years from the black hole, although the observation could not gauge its diameter, from inside to outside. The result marks the clearest observation of an obscured black hole in X-ray and gamma-ray `colours’, a span of energy nearly a million times wider than the window of visible light, from red to violet. Multi-wavelength studies are increasingly important to understanding black holes, as already demonstrated earlier this year. In May 2004, the European project known as the Astrophysical Virtual Observatory, in which ESA plays a major role, found 30 supermassive black holes that had previously escaped detection behind masking dust clouds. Note for editors This result will appear on The Astrophysical Journal. Besides Volker Beckmann, the author list includes Neil Gehrels, Pascal Favre, Roland Walter, Thierry Courvoisier, Pierre-Olivier Petrucci and Julien Malzac. For more information about the Astrophysical Virtual Observatory programme and how it has allowed European scientists to discover a number of previously hidden black holes, see: http://www.spacetelescope.org/news/html/heic0409.html More about Integral The International Gamma Ray Astrophysics Laboratory (Integral) is the first space observatory that can simultaneously observe celestial objects in gamma rays, X-rays and visible light. Integral was launched on a Russian Proton rocket on 17 October 2002 into a highly elliptical orbit around Earth. Its principal targets include regions of the galaxy where chemical elements are being produced and compact objects, such as black holes. More information on Integral can be

Del Macroscopio al Microscopio. Historia de la Medicina Científica (Epílogo

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Alberto Gómez Gutierrez

2002-04-01

Full Text Available

Parte de su libro presentado para ingresar como Miembro Asociado de la Academia Nacional de Medicina.

“La mente, y no el espacio, es la última frontera de la ciencia”.

John Horgan
El fin de la ciencia, 1998

El siglo XX, último siglo completo de nuestra cronología, ha sido llamado, con toda propiedad, el siglo de la ciencia. Nunca antes se hizo tal énfasis en el conocimiento analítico y la racionalidad como ejes de la cultura. Sin embargo, la racionalidad, entendida como la posibilidad de describir razones o causas para todos los eventos de la naturaleza, se encontró con la oposición de filósofos como sir Karl Popper, quien planteaba un indeterminismo general y, en especial, un indeterminismo en el ser humano. Esta postura, que exaltó el azar en la naturaleza y que parecía tener su principal sustento en la mecánica cuántica, se encontró a su vez con contradictores tan ilustres como el mismo Albert Einstein, quien al respecto acuñó su hermosa frase de estirpe vitalista cuando dijo: “Dios no juega a los dados”.

Este contrapunto entre científicos y filósofos, ha sido el telón de fondo de lo que podríamos llamar el acto central de la trama de la medicina científica en su edad madura. En un extremo, el determinismo resultante de las leyes de la física ha influido en el pensamiento de biólogos y médicos, hasta el punto de considerar que el organismo vivo no es más que la suma de sus funciones celulares y moleculares. Este extremo corresponde a los preceptos de la escuela mecanicista que tuvo su anterior apogeo en el siglo XVIII, cuando los iatrofísicos, iatroquímicos y iatromecánicos dejaron una visión consolidada de su percepción reduccionista en la citada obra de Julien Offray de la Mettrie titulada L´homme machine. Hoy en día siguen publicándose obras mecanicistas como La fabrique de l´homme (1997 del profesor Jean-Paul Lévy, en

Editorial: Focus on Laser- and Beam-Driven Plasma Accelerators

Science.gov (United States)

Joshi, Chan; Malka, Victor

2010-04-01

Persson, K Osvay, C-G Wahlström, D C Carroll, P McKenna, A Flacco and V Malka Proton acceleration by moderately relativistic laser pulses interacting with solid density targets Erik Lefebvre, Laurent Gremillet, Anna Lévy, Rachel Nuter, Patrizio Antici, Michaël Carrié, Tiberio Ceccotti, Mathieu Drouin, Julien Fuchs, Victor Malka and David Neely Holographic visualization of laser wakefields P Dong, S A Reed, S A Yi, S Kalmykov, Z Y Li, G Shvets, N H Matlis, C McGuffey, S S Bulanov, V Chvykov, G Kalintchenko, K Krushelnick, A Maksimchuk, T Matsuoka, A G R Thomas, V Yanovsky and M C Downer The scaling of proton energies in ultrashort pulse laser plasma acceleration K Zeil, S D Kraft, S Bock, M Bussmann, T E Cowan, T Kluge, J Metzkes, T Richter, R Sauerbrey and U Schramm Plasma cavitation in ultraintense laser interactions with underdense helium plasmas P M Nilson, S P D Mangles, L Willingale, M C Kaluza, A G R Thomas, M Tatarakis, R J Clarke, K L Lancaster, S Karsch, J Schreiber, Z Najmudin, A E Dangor and K Krushelnick Radiation pressure acceleration of ultrathin foils Andrea Macchi, Silvia Veghini, Tatyana V Liseykina and Francesco Pegoraro Target normal sheath acceleration: theory, comparison with experiments and future perspectives Matteo Passoni, Luca Bertagna and Alessandro Zani Generation of a highly collimated, mono-energetic electron beam from laser-driven plasma-based acceleration Sanyasi Rao Bobbili, Anand Moorti, Prasad Anant Naik and Parshotam Dass Gupta Controlled electron acceleration in the bubble regime by optimizing plasma density Meng Wen, Baifei Shen, Xiaomei Zhang, Fengchao Wang, Zhangying Jin, Liangliang Ji, Wenpeng Wang, Jiancai Xu and Kazuhisa Nakajima A multidimensional theory for electron trapping by a plasma wake generated in the bubble regime I Kostyukov, E Nerush, A Pukhov and V Seredov Investigation of the role of plasma channels as waveguides for laser-wakefield accelerators T P A Ibbotson, N Bourgeois, T P Rowlands-Rees, L S Caballero, S I

Revista História da Educação, v. 13, n. 27, 2009

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RHE Asphe

2011-03-01

didáticos como suporte das práticas pedagógicas, mas indicou também que, embora as anotações nos cadernos tenham sido baseadas nos livros adotados, estes não eram seguidos religiosamente, pois há omissões, acréscimos e interferências que tanto podem ser atribuídos a outros livros utilizados quanto aos próprios professores das disciplinas.

Os professores Maria Aparecida Muccilo e Newton César Balzan em seu trabalho Gestão: elementos de uma realidade vivenciada, têm como objeto de estudo o conceito de gestão que vem sendo instituído pela Secretaria de Estado da Educação do Estado de São Paulo a partir de meados da década de 1990, através de uma leitura da constituição da sociedade capitalista visando compreender a forma de gerir o setor público, em específico da educação no Estado de São Paulo.

Com o artigo O cultivo de valores exemplares: "galeriados patronos de escolas", de Antonio d’Avila (1980-1989 aprofessora Thabatha Aline Trevisan contribui para a história da educação brasileira e para o campo da imprensa periódica pedagógica. Neste artigo, destacam-se a produção de biografias, uma contribuição do educador Antônio d´Ávila para o periódico Jornal dos Professores, publicação do Centro do Professorado Paulista (CPP.

A professora Dóris Bittencourt Almeida, com o artigo As memórias e a história da educação: aproximações teórico e metodológicas, reflete sobre as contribuições da memória e da história oral para a história da educação. Tais reflexões foram fundamentais na construção de um estudo referente à formação docente rural, durante as décadas de 1950 e 1960. Assim, por meio da metodologia da história oral, procurou analisar o processo de memória de sujeitos discentes e docentes da Escola Normal Rural de Osório/RS, a partir dos discursos e dos conteúdos de verdade produzidos em entrevistas.

O texto Um estudo sobre a leitura analytica