WorldWideScience

Sample records for jules saltman

  1. Saltman on solidarity.

    Science.gov (United States)

    Brown, Lawrence D; Chinitz, David P

    2015-01-01

    Richard Saltman suggests that solidarity, a cherished notion at the heart of West European health care systems is being reconsidered in the light of today's austere economic conditions. Solidarity, he argues, has always been a flexible moral guideline, one that allows for policy responses, such as limitations on health benefits or increased out of pocket payments, that challenging fiscal conditions are said to demand. Here we consider what the basic elements in solidarity - universality, redistribution, and uniformity-- mean in health as compared to other social policy realms such as pensions. Traditionally, the commitment to solidarity said little about the contents of services, but the latter is perhaps subject to increasing scrutiny under the health policy microscope. Saltman is right to emphasize the conceptual and cross-national flexibility of solidarity, but the notion retains a solid and durable core that continues to give valuable direction to policymakers in search of acceptable strategies and structures for decision making.

  2. JULES-ANTOINE REGNAULD

    Directory of Open Access Journals (Sweden)

    Jaime Wisniak

    2015-01-01

    Full Text Available Jules - Antoine Regnauld (1822 - 1895, médico y farmacéutico francés q ue realizó investigaciones sobre los alcaloides midriáticos (como la atropina, fenómenos electroquímicos, fuerza electromotriz, amalgamas, propiedades de mezclado en disoluciones salinas, fisiología, electrofisiología, fluorescencia de órganos vivos, quím ica médica, anestesia y fenómenos de visión. Como resultado de ellos inventó un nuevo procedimiento para medir la fuerza electromotriz (método de oposición, y desarrolló una explicación de la influencia de la electricidad sobre los músculos y la visión bi nocular.

  3. Discover Paris with Jules Verne.

    Science.gov (United States)

    Hudson, Anna E.

    1996-01-01

    An approach to teaching French literature that uses a Jules Verne novel published only in 1994 is described. The novel, "Paris in the 20th Century," is the basis for a series of written and oral exercises about the novel, its social and cultural context, the author, and the actual changes that have occurred in Paris in comparison with…

  4. Jules Horowitz Reactor, basic design

    Energy Technology Data Exchange (ETDEWEB)

    Bergamaschi, Y.; Bouilloux, Y.; Chantoin, P.; Guigon, B.; Bravo, X.; Germain, C.; Rommens, M.; Tremodeux, P

    2003-07-01

    Since the shutdown of the SILOE reactor in 1997, the OSIRIS reactor has ensured the needs regarding technological irradiation at CEA including those of its industrial partners and customers. The Jules Horowitz Reactor will replace it. It has the ambition to provide the necessary nuclear data and maintain a fission research capacity in Europe after 2010. This capacity should be service-oriented. It will be established in Cadarache. The Jules Horowitz reactor will also: - represent a significant step in term of performances and experimental capabilities, - be designed with a high flexibility, in order to satisfy the current demand from European industry, research and be able to accommodate future requirements, - reach a high level of safety, according to the best current practice. This paper will present the main functionalities and the design options resulting from the 'preliminary design' studies. (authors)

  5. Astronomy and astronomers in Jules Verne's novels

    Science.gov (United States)

    Crovisier, Jacques

    2011-06-01

    Almost all the Voyages Extraordinaires written by Jules Verne refer to astronomy. In some of them, astronomy is even the leading theme. However, Jules Verne was basically not learned in science. His knowledge of astronomy came from contemporaneous popular publications and discussions with specialists among his friends or his family. In this article, I examine, from the text and illustrations of his novels, how astronomy was perceived and conveyed by Jules Verne, with errors and limitations on the one hand, with great respect and enthusiasm on the other hand. This informs us on how astronomy was understood by an ``honnête homme'' in the late 19th century.

  6. Jules Verne's Metaphor of the Iron Cage

    NARCIS (Netherlands)

    Ossewaarde, Marinus R.R.

    2010-01-01

    Max Weber's concept of the iron cage has become a byword in the scholarly world since the publication in 1930 of Talcott Parsons’ translation of The Protestant Ethic and the Spirit of Capitalism. What is less well-known is that Jules Verne had earlier used the iron cage metaphor in Twenty Thousand

  7. Jules Verne's Metaphor of the Iron Cage

    NARCIS (Netherlands)

    Ossewaarde, M.R.R.

    2010-01-01

    Max Weber's concept of the iron cage has become a byword in the scholarly world since the publication in 1930 of Talcott Parsons’ translation of The Protestant Ethic and the Spirit of Capitalism. What is less well-known is that Jules Verne had earlier used the iron cage metaphor in Twenty Thousand L

  8. Jules Verne - a new polishing technique related to FJP

    NARCIS (Netherlands)

    Booij, S.M.; Fähnle, O.W.; Meeder, M.; Wons, T.; Braat, J.J.M.

    2003-01-01

    A variation on the fluid jet polishing (FJP) technique, arbitrarily named Jules Verne (JV), will be described in this article. Jules Verne is a glass processing technique that removes material due to the fact that the tool and the surface are in close contact, and a slurry moves in between the tool

  9. Jules Verne - a new polishing technique related to FJP

    NARCIS (Netherlands)

    Booij, S.M.; Fähnle, O.W.; Meeder, M.; Wons, T.; Braat, J.J.M.

    2003-01-01

    A variation on the fluid jet polishing (FJP) technique, arbitrarily named Jules Verne (JV), will be described in this article. Jules Verne is a glass processing technique that removes material due to the fact that the tool and the surface are in close contact, and a slurry moves in between the tool

  10. Planets, comets and small bodies in Jules Verne's novels

    Science.gov (United States)

    Crovisier, J.

    2011-10-01

    Almost all the Voyages Extraordinaires written by Jules Verne refer to astronomy. In some of them, astronomy is even the leading theme. However, Jules Verne was basically not learned in science. His knowledge of astronomy came from contemporaneous popular publications and discussions with specialists among his friends or his family. In this contribution, I examine, from selected texts and illustrations of his novels, how astronomy — and especially planetary science — was perceived and conveyed by Jules Verne, with errors and limitations on the one hand, with great respect and enthusiasm on the other hand.

  11. Jules Verne Mare Soils as Revealed by Clementine UVVIS Data

    Science.gov (United States)

    Yingst, R. A.; Head, J. W.

    1999-03-01

    To determine the nature of potentially low-Ca pyroxene (noritic) spectra in six South Pole-Aitken basin mare deposits, we undertake a multispectral analysis of a representative of these deposits, that associated with Jules Verne crater.

  12. Sharp and the Jules Verne Launcher

    Science.gov (United States)

    Hunter, John; Cartland, Harry

    1996-03-01

    Lawrence Livermore National Laboratory (LLNL) has built the worlds largest hydrogen gas gun called SHARP, (Super High Altitude Research Project). Originally designed to launch 5 kg to a 450 km altitude, SHARP is configured horizontally at Site 300 in Tracy, California. SHARP is successfully delivering 5 kg scramjets at Mach 9 in aerophysics tests. Some of the results of the scramjet tests are enlightening and are presented insofar as they are relevant to future launches into space. Using a light gas gun to launch payloads into orbit has been analyzed. We look at LEO (Low Earth Orbit), GEO (Geosynchronous Earth Orbit), and LO (Lunar Orbit). We present a conceptual design for a large light gas gun called the Jules Verne Launcher (JVL). The JVL can deliver 3.3 metric tons to a 500 km low earth orbit. We anticipate one launch per day. We present the history of light gas guns, the SHARP design and performance, and the JVL design. Another section is devoted to the vehicle environment and resultant design. Lastly, we present a cost analysis. Our results indicated that the JVL will be able to deliver 1000 metric tons of payload to LEO yearly. The cost will be 5% of the best US rocket delivery cost. This technology will enable the next phase of man's exploration of space.

  13. Coupled carbon-nitrogen land surface modelling for UK agricultural landscapes using JULES and JULES-ECOSSE-FUN (JEF)

    Science.gov (United States)

    Comyn-Platt, Edward; Clark, Douglas; Blyth, Eleanor

    2016-04-01

    The UK is required to provide accurate estimates of the UK greenhouse gas (GHG; CO2, CH4 and N2O) emissions for the UNFCCC (United Nations Framework Convention on Climate Change). Process based land surface models (LSMs), such as the Joint UK Land Environment Simulator (JULES), attempt to provide such estimates based on environmental (e.g. land use and soil type) and meteorological conditions. The standard release of JULES focusses on the water and carbon cycles, however, it has long been suggested that a coupled carbon-nitrogen scheme could enhance simulations. This is of particular importance when estimating agricultural emission inventories where the carbon cycle is effectively managed via the human application of nitrogen based fertilizers. JULES-ECOSSE-FUN (JEF) links JULES with the Estimation of Carbon in Organic Soils - Sequestration and Emission (ECOSSE) model and the Fixation and Uptake of Nitrogen (FUN) model as a means of simulating C:N coupling. This work presents simulations from the standard release of JULES and the most recent incarnation of the JEF coupled system at the point and field scale. Various configurations of JULES and JEF were calibrated and fine-tuned based on comparisons with observations from three UK field campaigns (Crichton, Harwood Forest and Brattleby) specifically chosen to represent the managed vegetation types that cover the UK. The campaigns included flux tower and chamber measurements of CO2, CH4 and N2O amongst other meteorological parameters and records of land management such as application of fertilizer and harvest date at the agricultural sites. Based on the results of these comparisons, JULES and/or JEF will be used to provide simulations on the regional and national scales in order to provide improved estimates of the total UK emission inventory.

  14. Army After Next, Airland Battle 2000, Futuristic Concepts or Jules Verne?

    Science.gov (United States)

    1998-04-14

    service or government agency. STRATEGY RESEARCH PROJECT ARMY AFTER NEXT, AIRLAND BATTLE 2000, FUTURISTIC CONCEPTS OR JULES VERNE ? BY...AIRLAND BATTLE 2000, FUTURISTIC CONCEPTS OR JULES VERNE ? by LTC Francis G. Mahon Dr. Douglas V. Johnson Project Advisor Colonel Ronald Ouellette...Battle 2000, Futuristic Concepts or Jules Verne ? FORMAT: Strategy Research Project DATE: 14 April 1998 PAGES: 67 CLASSIFICATION

  15. Jules Verne: a new polishing technique related to FJP

    Science.gov (United States)

    Booij, Silvia M.; Faehnle, Oliver W.; Meeder, Mark; Wons, Torsten; Braat, Joseph J. M.

    2004-01-01

    A variation on the fluid jet polishing (FJP) technique, arbitrarily named Jules Verne (JV), will be described in this article. Jules Verne is a glass processing technique that removes material due to the fact that the tool and the surface are in close contact, and a slurry moves in between the tool and the surface. This approach has both advantages and disadvantages with respect to the original FJP modus: it enables a feed-controlled machining process, but deeper lying areas are harder to reach. A simulation model will be presented that predicts the flow of the slurry in the Jules Verne setup, which is followed by the computation of the trajectories of the particles in the flow. Furthermore, experimental data will be reported demonstrating the feasibility of the JV idea. A model will also be presented simulating the interaction between the surface and the impinging abrasives at a microscopic level, enabling the prediction of the final surface roughness.

  16. Land surface parameter optimisation through data assimilation: the adJULES system

    Science.gov (United States)

    Raoult, Nina; Jupp, Tim; Cox, Peter

    2017-04-01

    Land-surface models (LSMs) are crucial components of the Earth system models (ESMs) that are used to make coupled climate-carbon cycle projections for the 21st century. The Joint UK Land Environment Simulator (JULES) is the land-surface model used in the climate and weather forecast models of the UK Met Office. JULES is also extensively used offline as a land-surface impacts tool, forced with climatologies into the future. In this study, JULES is automatically differentiated with respect to JULES parameters using commercial software from FastOpt, resulting in an analytical gradient, or adjoint, of the model. Using this adjoint, the adJULES parameter estimation system has been developed to search for locally optimum parameters by calibrating against observations. We present adJULES in a data assimilation framework and demonstrate its ability to improve the model-data fit using eddy-covariance measurements of gross primary production (GPP) and latent heat (LE) fluxes. adJULES also has the ability to calibrate over multiple sites simultaneously. This feature is used to define new optimised parameter values for the five plant functional types (PFTs) in JULES. The optimised PFT-specific parameters improve the performance of JULES at over 85% of the sites used in the study, at both the calibration and evaluation stages. The new improved parameters for JULES are presented along with the associated uncertainties for each parameter.

  17. The Jules Verne island; L'Ile de Jules Verne

    Energy Technology Data Exchange (ETDEWEB)

    Sigfusson, T.I. [Universite d' Islande, Reykjavik, et Icelandic New Energy, Reykjavik (Iceland)

    2004-11-01

    During a thousand of years since its colonization by the Vikings in 874, Iceland has been practically an energy-less country. The French imaginative writer Jules Verne published his novel 'the mystery island' in 1874, i.e. exactly at the time of the first millennium of existence of the Icelandic people. In his book, J. Verne has imagined an island where the energy source was hydrogen produced by water electrolysis. Iceland is progressively building an hydrogen-based society like the one of J. Verne's dream. This article describes the path to follow to reach such a society: energy situation of Iceland today, history of energy conversion technologies, environmental impacts, feasibility of an hydrogen-based economy, 50 years transition era between petroleum product and hydrogen uses in the transportation sector, ECTOS (ecological city transport system) project, cooperation with other European countries (in particular France), hydrogen production and storage technologies, research on metal hydrides, teaching and information dissemination program. (J.S.)

  18. [The wanderings of Jules Cloquet and Gustave Flaubert].

    Science.gov (United States)

    Dumont, M

    1988-01-01

    This is the story of a picaresque journey in France and in Corsica of Jules Cloquet (1790-1883), the French anatomist who described the well-known Cloquet's node and of Gustave Flaubert (1821-1880), the famous author of "Madame Bovary" and of many others novels. They were two vagabonds, Cloquet watching with slackness the young womanizering Flaubert. At 64 years of age, the lazy and meddlesome Cloquet stopped operating and writing. Surrounded by honors, he died at the age of 93, leaving his eponym to the Cloquet's node.

  19. The launching of the construction of the Jules Horowitz Reactor; Lancement de la construction du reacteur de recherche Jules Horowitz

    Energy Technology Data Exchange (ETDEWEB)

    Anon

    2007-03-15

    In March 2007 the French deputy minister of industry has officially launched the construction of the new research reactor called Jules Horowitz (RJH) on the Cea site of Cadarache. RJH, that is due to operate in 2014, will be used to study the aging process of irradiated materials in any type of reactors, the behaviour of new nuclear fuels irradiated in different configurations and scenarios, and to produce radionuclides for nuclear medicine and high-quality doped silicon for the electronics industry. The investment that reaches 500 million euros is dispatched between Cea (50%), EDF (20%), Areva (10%) and foreign contributors (20%). (A.C.)

  20. Jules Germain Cloquet (1790-1883)--drawing master and anatomist.

    Science.gov (United States)

    Loukas, Marios; El-Sedfy, Abraham; Tubbs, R Shane; Wartman, Christopher

    2007-11-01

    Jules Germain Cloquet, the famed French anatomist, surgeon, and professor, may not be remembered as one of the pioneers of hernia surgery; however, his contributions have provided surgeons with detailed anatomical descriptions that have been useful in developing innovative surgical techniques. Cloquet has many eponyms associated with him, including: Cloquet's fascia, Cloquet's gland or lymph node of Cloquet, Cloquet's hernia, Cloquet's ligament, Cloquet's canal, and Cloquet's septum. A man blessed with artistic talents, Cloquet was the author of many theses, as well as anatomical volumes that were comparable to the works of other great anatomists of his time. His first thesis, entitled Recherches Anatomiques sur les Hernies de l'Abdomen, described the locations where inguinal and crural herniae are more likely to occur in terms of the cremaster muscle, the peritoneum, and the spermatic vessels. Wax sculpture training required extensive knowledge in the natural sciences, anatomy, physiology, and pathology, as were acquired by Jules Cloquet as a pupil of Achille-Cléophas Flaubert, the father of the famous French novelist Gustave Flaubert (author of Madame Bovary). Cloquet attracted many pupils with his innovative teaching style and implementation of anatomical preparations, drawings, and sketches on the black board with chalk. The legacy of this famed individual lives on today in the anatomical structures described by Cloquet.

  1. In Jules Verne's Footsteps: Seismology in the source

    Science.gov (United States)

    Ellsworth, Bill; Ito, Hisao; Malin, Peter; Abercrombie, Rachel

    When Professor Otto Lidenbrock led his little band to the center of the Earth in Jules Verne's 1864 classic novel, the intrepid adventurers needed little more than practical 19th century clothes to provide them with comfort and protection. How different the science of earthquakes would be if conditions in the Earth were really so friendly to the would-be observer. Even the operation of seismic sensors at the relatively modest depth of 2-3 km, roughly the depth of the shallowest crustal earthquakes, requires careful precautions against the effects of unstable materials, temperature, pressure, and water for successful long-term observations to be made. Indeed, the handful of successful deep borehole experiments that have been conducted to date have depended on simple sensors with limited bandwidth and dynamic range, and have yielded data that were not ideally suited to investigating the details of the earthquake source.

  2. Land-surface parameter optimisation using data assimilation techniques: the adJULES system V1.0

    Science.gov (United States)

    Raoult, Nina M.; Jupp, Tim E.; Cox, Peter M.; Luke, Catherine M.

    2016-08-01

    Land-surface models (LSMs) are crucial components of the Earth system models (ESMs) that are used to make coupled climate-carbon cycle projections for the 21st century. The Joint UK Land Environment Simulator (JULES) is the land-surface model used in the climate and weather forecast models of the UK Met Office. JULES is also extensively used offline as a land-surface impacts tool, forced with climatologies into the future. In this study, JULES is automatically differentiated with respect to JULES parameters using commercial software from FastOpt, resulting in an analytical gradient, or adjoint, of the model. Using this adjoint, the adJULES parameter estimation system has been developed to search for locally optimum parameters by calibrating against observations. This paper describes adJULES in a data assimilation framework and demonstrates its ability to improve the model-data fit using eddy-covariance measurements of gross primary production (GPP) and latent heat (LE) fluxes. adJULES also has the ability to calibrate over multiple sites simultaneously. This feature is used to define new optimised parameter values for the five plant functional types (PFTs) in JULES. The optimised PFT-specific parameters improve the performance of JULES at over 85 % of the sites used in the study, at both the calibration and evaluation stages. The new improved parameters for JULES are presented along with the associated uncertainties for each parameter.

  3. A new MTR fuel for a new MTR reactor: UMo for the Jules Horowitz reactor

    Energy Technology Data Exchange (ETDEWEB)

    Guigon, B. [CEA Cadarache, F-13108 Saint Paul lez Durance (France); Vacelet, H. [CERCA, Romans (France); Dornbusch, D. [Technicatome, Aix en Provence (France)

    2000-07-01

    Within some years, the Jules Horowitz Reactor will be the only working experimental reactor (material and fuel testing reactor) in France. It will have to provide facilities for a wide range of needs from activation analysis to power reactor fuel qualification. In this paper the main characteristics of the Jules Horowitz Reactor are presented. Safety criteria are explained. Finally, merits and disadvantages of UMo compared to the standard U{sub 3}Si{sub 2} fuel are discussed. (author)

  4. Jules Verne Voyager: A Web Interactive Tool for Comparative Planetology

    Science.gov (United States)

    Estey, L.; Pappalardo, R.; Meertens, C.

    2004-12-01

    A Web interactive map tool called "Jules Verne Voyager" was originally developed in 1999 by UNAVCO and continues to evolve. The Voyager tool can easily be used for comparative planetology studies by grades 8-14. Thematic mapping datasets, now totaling about 70 Gb, can be accessed by the tool and include global-scale maps of the inner solar system planets and moons, plus Jupiter and the Galilean moons. The map images are viewed on a Web browser created on demand by the server system. On the client-side, only a Java-enabled browser is required, and the Voyager Java applet runs well with common browsers like Netscape, Mozilla, Opera, and Internet Explorer. The applet sends a key-value pair URL to the http://jules.unavco.org server which queues incoming requests and sends them to a bank of computers dedicated to map image creation. The engine for map image creation makes use of the "Generic Mapping Tools" (GMT) software of Paul Wessel and Walter Smith, followed by image conversion of the GMT-created PostScript to GIF for raster image export and display back on the client browser. Because of the GMT-based engine on the server system, the student user can easily create the same type of images from real planetary data that researchers create. The tool also gives a student the ability to switch background datasets and overlay certain other thematic datasets, thus providing a minimal GIS capability. To our knowledge, the map tool has not yet formally been used in a 8-14 classroom environment, though informal use by students and teachers in these grades suggest that it would be well received. The server system is currently capable of handing a moderate level of requests that would result from classroom use; for example, as a system benchmark, over 800 Voyager images were created and served in about an hour during a DLESE 2003 annual meeting workshop. The Voyager map tool is being used by instructors in earth science and comparative planetology as a means to create customized

  5. A new MTR fuel for a new MTR reactor: UMo for the Jules Horowitz reactor

    Energy Technology Data Exchange (ETDEWEB)

    Guigon, B. [CEA Cadarache, Dir. de l' Energie Nucleaire DEN, Reacteur Jules Horowitz, 13 - Saint-Paul-lez-Durance (France); Vacelet, H. [Compagnie pour l' Etude et la Realisation de Combustibles Atomiques, CERCA, Etablissement de Romans, 26 (France); Dornbusch, D. [Technicatome, Service d' Architecture Generale, 13 - Aix-en-Provence (France)

    2003-07-01

    Within some years, the Jules Horowitz Reactor will be the only working experimental reactor (material and fuel testing reactor) in France. It will have to provide facilities for a wide range of needs: from activation analysis to power reactor fuel qualification. In this paper will be presented the main characteristics of the Jules Horowitz Reactor: its total power, neutron flux, fuel element... Safety criteria will be explained. Finally merits and disadvantages of UMo compared to the standard U{sub 3}Si{sub 2} fuel will be discussed. (authors)

  6. Quantifying the Impact of Tropospheric Ozone on Crops Productivity at regional scale using JULES-crop

    Science.gov (United States)

    Leung, F.

    2016-12-01

    Tropospheric ozone (O3) is the third most important anthropogenic greenhouse gas. It is causing significant crop production losses. Currently, O3 concentrations are projected to increase globally, which could have a significant impact on food security. The Joint UK Land Environment Simulator modified to include crops (JULES-crop) is used here to quantify the impacts of tropospheric O3 on crop production at the regional scale until 2100. We evaluate JULES-crop against the Soybean Free-Air-Concentration-Enrichment (SoyFACE) experiment in Illinois, USA. Experimental data from SoyFACE and various literature sources is used to calibrate the parameters for soybean and ozone damage parameters in soybean in JULES-crop. The calibrated model is then applied for a transient factorial set of JULES-crop simulations over 1960-2005. Simulated yield changes are attributed to individual environmental drivers, CO2, O3 and climate change, across regions and for different crops. A mixed scenario of RCP 2.6 and RCP 8.5 climatology and ozone are simulated to explore the implication of policy. The overall findings are that regions with high ozone concentration such as China and India suffer the most from ozone damage, soybean is more sensitive to O3 than other crops. JULES-crop predicts CO2 fertilisation would increase the productivity of vegetation. This effect, however, is masked by the negative impacts of tropospheric O3. Using data from FAO and JULES-crop estimated that ozone damage cost around 55.4 Billion USD per year on soybean. Irrigation improves the simulation of rice only, and it increases the relative ozone damage because drought can reduce the ozone from entering the plant stomata. RCP 8.5 scenario results in a high yield for all crops mainly due to the CO2 fertilisation effect. Mixed climate scenarios simulations suggest that RCP 8.5 CO2 concentration and RCP 2.6 O3 concentration result in the highest yield. Further works such as more crop FACE-O3 experiments and more Crop

  7. On the Verbal Art of a Modern Painter: The Work of Jules Kirschenbaum.

    Science.gov (United States)

    Gandelman, Claude

    1989-01-01

    Notes that Jules Kirschenbaum, a modern American artist whose work integrates inscriptions and figurative painting, studied under the masters of abstract expressionism yet exhibited with protagonists of "magic realism." States that his later work took a wholly different turn--it became art about meaning and the "meaning of meaning." (RS)

  8. Multi-site evaluation of the JULES land surface model using global and local data

    Directory of Open Access Journals (Sweden)

    D. Slevin

    2015-02-01

    Full Text Available This study evaluates the ability of the JULES land surface model (LSM to simulate photosynthesis using local and global data sets at 12 FLUXNET sites. Model parameters include site-specific (local values for each flux tower site and the default parameters used in the Hadley Centre Global Environmental Model (HadGEM climate model. Firstly, gross primary productivity (GPP estimates from driving JULES with data derived from local site measurements were compared to observations from the FLUXNET network. When using local data, the model is biased with total annual GPP underestimated by 16% across all sites compared to observations. Secondly, GPP estimates from driving JULES with data derived from global parameter and atmospheric reanalysis (on scales of 100 km or so were compared to FLUXNET observations. It was found that model performance decreases further, with total annual GPP underestimated by 30% across all sites compared to observations. When JULES was driven using local parameters and global meteorological data, it was shown that global data could be used in place of FLUXNET data with a 7% reduction in total annual simulated GPP. Thirdly, the global meteorological data sets, WFDEI and PRINCETON, were compared to local data to find that the WFDEI data set more closely matches the local meteorological measurements (FLUXNET. Finally, the JULES phenology model was tested by comparing results from simulations using the default phenology model to those forced with the remote sensing product MODIS leaf area index (LAI. Forcing the model with daily satellite LAI results in only small improvements in predicted GPP at a small number of sites, compared to using the default phenology model.

  9. The climate responses of tropical and boreal ecosystems with an improved land surface model (JULES)

    Science.gov (United States)

    Harper, Anna; Friedlingstein, Pierre; Cox, Peter; Wiltshire, Andy; Jones, Chris

    2016-04-01

    The Joint UK Land Environment Simulator (JULES) is the land surface of the next generation UK Earth System Model (UKESM1). Recently, JULES was updated with new plant functional types and physiology based on a global plant trait database. These developments improved the simulation of terrestrial gross and net primary productivity on local and global scales, and enabled a more realistic representation of the global distribution of vegetation. In this study, we explore the present-day distribution of ecosystems and their vulnerability to climate change in JULES with these improvements, focusing on tropical and boreal ecosystems. Changes to these ecosystems will have implications for biogeophysical and biogeochemical feedbacks to climate change and need to be understood. First, we examine the simulated and observed rainforest-savannah boundary, which is strongly related to annual precipitation and the maximum climatological water deficit. Second, we assess the length of growing season and biomass stored in boreal ecosystems, where 20th century warming has likely extended the growing season. In each case, we first evaluate the ability of JULES to capture observed climate-vegetation relationships and trends. Finally, we run JULES to 2100 using climate data from 3 models and 2 RCP scenarios, and examine potential 21st century changes to these ecosystems. For example, do the tropical forests shrink in response to changes in tropical rainfall seasonality? And, how does the composition of boreal ecosystems change in response to climate warming? Given the potential for climate feedbacks and the inherent value in these ecosystems, it is essential to assess their responses to a range of climate change scenarios.

  10. [Professor Jules Gavarret (1809-1890) and the application of mathematics and physics to medicine].

    Science.gov (United States)

    Beyneix, A

    2001-01-01

    Professor Jules Gavarret has undertaken pretigious offices, has accumulated various titles and honours and has left an abundant bibliography about physics and chemistry of life phenomenon. To recount the career of one of the academics who were benefited the traditional medicine of the progress achieved in physical and mathematical sciences give us the opportunity of recalling one of the great Parisian personalities of 19th Century who had not been appreciated for too long.

  11. Pierre Samuel et Jules Vuillemin : mathématiques et philosophie

    OpenAIRE

    2014-01-01

    National audience; In this article I aim to present an actual modality of relationship between mathematics and philosophy. To this purpose, I will consider a relatively recent project in philosophy of mathematics by taking as a case study Pierre Samuel's and Jules Vuillemin's reflections and contributions dealing with a general concept of structure in line with Nicolas Bourbaki, and by examining more specifically the notion of universal problem.; Je me propose dans cet article de présenter un...

  12. Assimilating ESA-CCI Soil Moisture into the JULES-EMPIRE Data Assimilation System

    Science.gov (United States)

    Quaife, T. L.; Black, E.; Browne, P.; Lewis, J.

    2015-12-01

    Land surface models, such as the Joint UK Land Environment Simulator (JULES, the land surface component of the Hadley Centre models) are used in a wide variety of applications, such as climate modelling, flood prediction and crop yield forecasting. However, how best to implement Data Assimilation (DA) for these models remains an open question. At a fundamental level these models are very different from atmospheric models for which traditional DA was developed. This poster describes the integration of JULES with the EMPIRE framework. EMPIRE (Employing MPI for Researching Ensembles) implements a test bed for ensemble based DA techniques that makes use of MPI message passing to exploit all available processing power. In particular EMPIRE contains several flavours of Particle Filter which show promise for the land surface DA problem. Examples of assimilating soil moisture observations from the ESA CCI data set into JULES are given for a number of sites in Africa. The model ensemble is generated by considering uncertainty in the driving data taken from the TAMSAT operational rainfall product. The results show considerable improvement in the modelled soil moisture and in particular the seasonal timing of the soil wetness.

  13. Performance of the JULES land surface model for UK Biogenic VOC emissions

    Science.gov (United States)

    Hayman, Garry; Comyn-Platt, Edward; Vieno, Massimo; Langford, Ben

    2017-04-01

    Emissions of biogenic non-methane volatile organic compounds (NMVOCs) are important for air quality and tropospheric composition. Through their contribution to the production of tropospheric ozone and secondary organic aerosol (SOA), biogenic VOCs indirectly contribute to climate forcing and climate feedbacks [1]. Biogenic VOCs encompass a wide range of compounds and are produced by plants for growth, development, reproduction, defence and communication [2]. There are both biological and physico-chemical controls on emissions [3]. Only a few of the many biogenic VOCs are of wider interest and only two or three (isoprene and the monoterpenes, α- and β-pinene) are represented in chemical transport models. We use the Joint UK Land Environment Simulator (JULES), the UK community land surface model, to estimate biogenic VOC emission fluxes. JULES is a process-based model that describes the water, energy and carbon balances and includes temperature, moisture and carbon stores [4, 5]. JULES currently provides emission fluxes of the 4 largest groups of biogenic VOCs: isoprene, terpenes, methanol and acetone. The JULES isoprene scheme uses gross primary productivity (GPP), leaf internal carbon and the leaf temperature as a proxy for the electron requirement for isoprene synthesis [6]. In this study, we compare JULES biogenic VOC emission estimates of isoprene and terepenes with (a) flux measurements made at selected sites in the UK and Europe and (b) gridded estimates for the UK from the EMEP/EMEP4UK atmospheric chemical transport model [7, 8], using site-specific or EMEP4UK driving meteorological data, respectively. We compare the UK-scale emission estimates with literature estimates. We generally find good agreement in the comparisons but the estimates are sensitive to the choice of the base or reference emission potentials. References (1) Unger, 2014: Geophys. Res. Lett., 41, 8563, doi:10.1002/2014GL061616; (2) Laothawornkitkul et al., 2009: New Phytol., 183, 27, doi

  14. Representation of Dissolved Organic Carbon in the JULES Dynamic Global Vegetation Model

    Science.gov (United States)

    Nakhavali, Mahdi; Friedlingstein, Pierre; Guenet, Bertrand; Ciais, Philip

    2017-04-01

    Current global models of the carbon cycle consider only vertical gas exchanges between terrestrial or oceanic reservoirs and the atmosphere, hence not considering lateral transport of carbon from the continent to the oceans. This also means that such models implicitly consider that all the CO2 which is not respired to the atmosphere is stored on land, hence overestimating the land sink of carbon. Moving toward a boundless carbon cycle that is integrating the whole continuum from land to ocean to atmosphere is needed in order to better understand Earth's carbon cycle and to make more reliable projection of its future. Here we present an original representation of Dissolved Organic Carbon (DOC) processes in the Joint UK Land Environment Simulator (JULES). The standard version of JULES represent energy, water and carbon cycles and exchanges with the atmosphere, but only account for water run-off, not including export of carbon from terrestrial ecosystems to the aquatic environments. The aim of the project is to include in JULES a representation of DOC production in terrestrial soils, due to incomplete decomposition of organic matter, its decomposition to the atmosphere, and its export to the river network by leaching. In new developed version of JULES (JULES-DOCM), DOC pools, based on their decomposition rate, are classified into labile and recalcitrant within 3 meters of soil. Based on turnover rate, DOC coming from plant material pools and microbial biomass is directed to labile pool, while DOC from humus is directed to recalcitrant pool. Both of these pools have free (dissolved) and locked (adsorbed) form where just the free pool is subjected to decomposition and leaching. DOC production and decomposition are controlled by rate modifiers (moisture, temperature, vegetation fraction and decomposition rate) at each soil layer. Decomposed DOC is released to the atmosphere following a fixed carbon use efficiency. Leaching accounts for both surface (runoff) and

  15. Jules Verne Voyager, Jr: An Interactive Map Tool for Teaching Plate Tectonics

    Science.gov (United States)

    Hamburger, M. W.; Meertens, C. M.

    2010-12-01

    We present an interactive, web-based map utility that can make new geological and geophysical results accessible to a large number and variety of users. The tool provides a user-friendly interface that allows users to access a variety of maps, satellite images, and geophysical data at a range of spatial scales. The map tool, dubbed 'Jules Verne Voyager, Jr.', allows users to interactively create maps of a variety of study areas around the world. The utility was developed in collaboration with the UNAVCO Consortium for study of global-scale tectonic processes. Users can choose from a variety of base maps (including "Face of the Earth" and "Earth at Night" satellite imagery mosaics, global topography, geoid, sea-floor age, strain rate and seismic hazard maps, and others), add a number of geographic and geophysical overlays (coastlines, political boundaries, rivers and lakes, earthquake and volcano locations, stress axes, etc.), and then superimpose both observed and model velocity vectors representing a compilation of 2933 GPS geodetic measurements from around the world. A remarkable characteristic of the geodetic compilation is that users can select from some 21 plates' frames of reference, allowing a visual representation of both 'absolute' plate motion (in a no-net rotation reference frame) and relative motion along all of the world's plate boundaries. The tool allows users to zoom among at least three map scales. The map tool can be viewed at http://jules.unavco.org/VoyagerJr/Earth. A more detailed version of the map utility, developed in conjunction with the EarthScope initiative, focuses on North America geodynamics, and provides more detailed geophysical and geographic information for the United States, Canada, and Mexico. The ‘EarthScope Voyager’ can be accessed at http://jules.unavco.org/VoyagerJr/EarthScope. Because the system uses pre-constructed gif images and overlays, the system can rapidly create and display maps to a large number of users

  16. POSITIVISM, INDUSTRIAL REVOLUTION AND URBANISM - UTOPIA AND REALITY IN THE JULES VERNE'S NOVEL "THE BEGUM'S FORTUNE"

    Directory of Open Access Journals (Sweden)

    Daniel H. Valsecchi

    2009-01-01

    Full Text Available The aim of this article is to analyze negative consequences (social, political, psychological and so forth of utopian projects, which crippled society and people by negation of reality and at the same time oblige them to accept these plans. In order to do this we analyze characteristics of two constructions which are thoroughly depicted by Jules Verne: an Arms Fabric (Stahlstadt and a city which was mathematically built (France Ville. Furthermore there are reflections about positivism - i.e. the ground of these projects.

  17. Simulation of permafrost and seasonal thaw depth in the JULES land surface scheme

    Directory of Open Access Journals (Sweden)

    R. Dankers

    2011-04-01

    Full Text Available Land surface models (LSMs need to be able to simulate realistically the dynamics of permafrost and frozen ground. In this paper we evaluate the performance of the LSM JULES (Joint UK Land Environment Simulator, the stand-alone version of the land surface scheme used in Hadley Centre climate models, in simulating the large-scale distribution of surface permafrost. In particular we look at how well the model is able to simulate the seasonal thaw depth or active layer thickness (ALT. We performed a number of experiments driven by observation-based climate datasets. Visually there is a very good agreement between areas with permafrost in JULES and known permafrost distribution in the Northern Hemisphere, and the model captures 97% of the area where the permafrost coverage is at least 50% of the grid cell. However, the model overestimates the total extent as it also simulates permafrost where it occurs sporadically or only in isolated patches. Consistent with this we find a cold bias in the simulated soil temperatures, especially in winter. However, when compared with observations on end-of-season thaw depth from around the Arctic, the ALT in JULES is generally too deep. Additional runs at three sites in Alaska demonstrate how uncertainties in the precipitation input affect the simulation of soil temperatures by affecting the thickness of the snowpack and therefore the thermal insulation in winter. In addition, changes in soil moisture content influence the thermodynamics of soil layers close to freezing. We also present results from three experiments in which the standard model setup was modified to improve physical realism of the simulations in permafrost regions. Extending the soil column to a depth of 60 m and adjusting the soil parameters for organic content had relatively little effect on the simulation of permafrost and ALT. A higher vertical resolution improves the simulation of ALT, although a considerable bias still remains. Future model

  18. Simulation of permafrost and seasonal thaw depth in the JULES land surface scheme

    Directory of Open Access Journals (Sweden)

    R. Dankers

    2011-09-01

    Full Text Available Land surface models (LSMs need to be able to simulate realistically the dynamics of permafrost and frozen ground. In this paper we evaluate the performance of the LSM JULES (Joint UK Land Environment Simulator, the stand-alone version of the land surface scheme used in Hadley Centre climate models, in simulating the large-scale distribution of surface permafrost. In particular we look at how well the model is able to simulate the seasonal thaw depth or active layer thickness (ALT. We performed a number of experiments driven by observation-based climate datasets. Visually there is a very good agreement between areas with permafrost in JULES and known permafrost distribution in the Northern Hemisphere, and the model captures 97% of the area where the spatial coverage of the permafrost is at least 50%. However, the model overestimates the total extent as it also simulates permafrost where it occurs sporadically or only in isolated patches. Consistent with this we find a cold bias in the simulated soil temperatures, especially in winter. However, when compared with observations on end-of-season thaw depth from around the Arctic, the ALT in JULES is generally too deep. Additional runs at three sites in Alaska demonstrate how uncertainties in the precipitation input affect the simulation of soil temperatures by affecting the thickness of the snowpack and therefore the thermal insulation in winter. In addition, changes in soil moisture content influence the thermodynamics of soil layers close to freezing. We also present results from three experiments in which the standard model setup was modified to improve physical realism of the simulations in permafrost regions. Extending the soil column to a depth of 60 m and adjusting the soil parameters for organic content had relatively little effect on the simulation of permafrost and ALT. A higher vertical resolution improves the simulation of ALT, although a considerable bias still remains. Future model

  19. Global evaluation of gross primary productivity in the JULES land surface model v3.4.1

    Directory of Open Access Journals (Sweden)

    D. Slevin

    2017-07-01

    Full Text Available This study evaluates the ability of the JULES land surface model (LSM to simulate gross primary productivity (GPP on regional and global scales for 2001–2010. Model simulations, performed at various spatial resolutions and driven with a variety of meteorological datasets (WFDEI-GPCC, WFDEI-CRU and PRINCETON, were compared to the MODIS GPP product, spatially gridded estimates of upscaled GPP from the FLUXNET network (FLUXNET-MTE and the CARDAMOM terrestrial carbon cycle analysis. Firstly, when JULES was driven with the WFDEI-GPCC dataset (at 0. 5° × 0. 5° spatial resolution, the annual average global GPP simulated by JULES for 2001–2010 was higher than the observation-based estimates (MODIS and FLUXNET-MTE, by 25 and 8 %, respectively, and CARDAMOM estimates by 23 %. JULES was able to simulate the standard deviation of monthly GPP fluxes compared to CARDAMOM and the observation-based estimates on global scales. Secondly, GPP simulated by JULES for various biomes (forests, grasslands and shrubs on global and regional scales were compared. Differences among JULES, MODIS, FLUXNET-MTE and CARDAMOM on global scales were due to differences in simulated GPP in the tropics. Thirdly, it was shown that spatial resolution (0. 5° × 0. 5°, 1° × 1° and 2° × 2° had little impact on simulated GPP on these large scales, with global GPP ranging from 140 to 142 PgC year−1. Finally, the sensitivity of JULES to meteorological driving data, a major source of model uncertainty, was examined. Estimates of annual average global GPP were higher when JULES was driven with the PRINCETON meteorological dataset than when driven with the WFDEI-GPCC dataset by 3 PgC year−1. On regional scales, differences between the two were observed, with the WFDEI-GPCC-driven model simulations estimating higher GPP in the tropics (5° N–5° S and the PRINCETON-driven model simulations estimating higher GPP in the extratropics (30

  20. Sources of interannual yield variability in JULES-crop and implications for forcing with seasonal weather forecasts

    Directory of Open Access Journals (Sweden)

    K. E. Williams

    2015-06-01

    Full Text Available JULES-crop is a parametrisation of crops in the Joint UK Land Environment Simulator (JULES. We investigate the sources of the interannual variability in the modelled maize yield, using global runs driven by reanalysis data, with a view to understanding the impact of various approximations in the driving data and initialisation. The standard forcing dataset for JULES consists of a combination of meteorological variables describing precipitation, radiation, temperature, pressure, specific humidity and wind, at subdaily time resolution. We find that the main characteristics of the modelled yield can be reproduced with a subset of these variables and using daily forcing, with internal disaggregation to the model timestep. This has implications in particular for the use of the model with seasonal forcing data, which may not have been provided at subdaily resolution for all required driving variables. We also investigate the effect on annual yield of initialising the model with climatology on the sowing date. This approximation has the potential to considerably simplify the use of the model with seasonal forecasts, since obtaining observations or reanalysis output for all the initialisation variables required by JULES for the start date of the seasonal forecast would present significant practical challenges.

  1. [Citation errors: Uplavici (for Hlava) and William the Silent (for Jules Verne and Mignet)].

    Science.gov (United States)

    Lienhart, A

    2011-05-01

    A certain 'O Uplavici' was cited for more than fifty years, although he had never existed. This error probably came from a misinterpretation of the Czech language, in which the real author's name--Hlava--can mean 'Title'. It was finally recognized, which was not the case for the author of the sentence: 'I have no need of hope to take action, nor of success to persevere', it is still regularly attributed in France to William I, Prince of Orange, called the Silent. It is a mistake, and no serious reference certifies that an historical figure would have pronounced this sentence. It was written by the historian Mignet in 1841, to describe the character of William III, Prince of Orange and King of England. It was then used in 1875 by Jules Verne, to describe a character in 'The Mysterious Island'. Copyright © 2011. Published by Elsevier SAS.

  2. Jules Horowitz Reactor: Organisation for the Preparation of the Commissioning Phase and Normal Operation

    Energy Technology Data Exchange (ETDEWEB)

    Estrade, J.; Fabre, J. L.; Marcille, O. [French Alternative Energies end Atomic Energy Commission, Provence (France)

    2013-07-01

    The Jules Horowitz Reactor (JHR) is a new modern Material Testing Reactor (MTR) currently under construction at CEA Cadarache research centre in the south of France. It will be a major research facility in support to the development and the qualification of materials and fuels under irradiation with sizes and environment conditions relevant for nuclear power plants in order to optimise and demonstrate safe operations of existing power reactors as well as to support future reactors design. It will represent also an important research infrastructure for scientific studies dealing with material and fuel behaviour under irradiation. The JHR will contribute also to secure the production of radioisotope for medical application. This is a key public health stake. The construction of JHR which started in 2007 is going-on with target of commissioning by the end of 2017. The design of the reactor provides modern experimental capacity in support to R and D programs for the nuclear energy for the next 60 years. In parallel to the facility construction, the preparation of the future staff and of the organisation to operate the reactor safely, reliably and efficiently is an important issue. In this framework, many actions are in progress to elaborate: Ο the staffing and the organisational structure for the commissioning test phases and also for normal operation, Ο the documentation in support to the reactor operation (safety analysis report, general operating rules, procedures, instructions, ···), Ο the maintenance, in service and periodic test programs, Ο staff training programs by using dedicated facilities (simulator, ···) Ο commissioning test programs for ensuring that the layout of systems and subcomponents is completed in accordance with the design requirements, the specification performances and the safety criteria. These commissioning tests will also be helpful for transferring the knowledge on the installed systems to the operating group. This paper gives the

  3. Coupling between the JULES land-surface scheme and the CCATT-BRAMS atmospheric chemistry model (JULES-CCATT-BRAMS1.0: applications to numerical weather forecasting and the CO2 budget in South America

    Directory of Open Access Journals (Sweden)

    D. S. Moreira

    2013-08-01

    Full Text Available This article presents the coupling of the JULES surface model to the CCATT-BRAMS atmospheric chemistry model. This new numerical system is denominated JULES-CCATT-BRAMS. We demonstrate the performance of this new model system in relation to several meteorological variables and the CO2 mixing ratio over a large part of South America, focusing on the Amazon basin. The evaluation was conducted for two time periods, the wet (March and dry (September seasons of 2010. The model errors were calculated in relation to meteorological observations at conventional stations in airports and automatic stations. In addition, CO2 mixing ratios in the first model level were compared with meteorological tower measurements and vertical CO2 profiles were compared with observations obtained with airborne instruments. The results of this study show that the JULES-CCATT-BRAMS modeling system provided a significant gain in performance for the considered atmospheric fields relative to those simulated by the LEAF (version 3 surface model originally employed by CCATT-BRAMS. In addition, the new system significantly increases the ability to simulate processes involving air–surface interactions, due to the ability of JULES to simulate photosynthesis, respiration and dynamic vegetation, among other processes. We also discuss a wide range of numerical studies involving coupled atmospheric, land surface and chemistry processes that could be done with the system introduced here. Thus, this work presents to the scientific community a free modeling tool, with good performance in comparison with observational data and reanalysis model data, at least for the region and time period discussed here. Therefore, in principle, this model is able to produce atmospheric hindcast/forecast simulations at different spatial resolutions for any time period and any region of the globe.

  4. Vamos ao Brasil com Jules Verne?: processos editoriais e civilização nas Voyages Extraordinaires

    Directory of Open Access Journals (Sweden)

    Andréa Borges Leão

    2012-12-01

    Full Text Available No século XIX, uma rede de conhecimentos sobre as diferenças culturais dos povos americanos marcou a edição destinada à instrução e diversão da juventude francesa. Uma das 62 Voyages Extraordinaires de Jules Verne, publicadas por Pierre-Jules Hetzel, é ambientada entre o Peru e o Brasil: La Jangada, huit cents lieues sur l'Amazone (1881. Na produção de literatura juvenil que se desenvolve e expande no comércio transatlântico da livraria francesa, sobressai uma psicogênese do Brasil. Por esse ângulo, a via de análise aberta pelo sociólogo Norbert Elias ajudou a enfrentar o problema das emoções humanas, no romance de viagem, e a conceituar a atividade mimética no livro de ciência e recreação.In the 19th century, a net of knowledge about cultural differences of the populations of Americas imprint the edition assign to instruction and entertainment of the young French people. One of the 62 Voyages Extraordinaires of Jules Verne, published by Pierre-Jules Hetzel, is set between Peru and Brazil: La Jangada, huit cents lieues sur l'Amazone (Eight Hundred Leagues on the Amazon - 1881. Around the juvenile production that grows and expands in the transatlantic trade of the French bookstore, a psychogenesis of Brazil shines through. By this angle, the analytic way opened by the sociologist Norbert Elias helps to face the problem of the human emotions in the travel novel and also helps to consider the mimetic activity in the book of science and entertainment.

  5. Love stories can be unpredictable: Jules et Jim in the vortex of life.

    Science.gov (United States)

    Dercole, Fabio; Rinaldi, Sergio

    2014-06-01

    Love stories are dynamic processes that begin, develop, and often stay for a relatively long time in a stationary or fluctuating regime, before possibly fading. Although they are, undoubtedly, the most important dynamic process in our life, they have only recently been cast in the formal frame of dynamical systems theory. In particular, why it is so difficult to predict the evolution of sentimental relationships continues to be largely unexplained. A common reason for this is that love stories reflect the turbulence of the surrounding social environment. But we can also imagine that the interplay of the characters involved contributes to make the story unpredictable-that is, chaotic. In other words, we conjecture that sentimental chaos can have a relevant endogenous origin. To support this intriguing conjecture, we mimic a real and well-documented love story with a mathematical model in which the environment is kept constant, and show that the model is chaotic. The case we analyze is the triangle described in Jules et Jim, an autobiographic novel by Henri-Pierre Roché that became famous worldwide after the success of the homonymous film directed by François Truffaut.

  6. Catálogo de los puentes proyectados por Jules Sagebien en la provincia de Matanzas.

    Directory of Open Access Journals (Sweden)

    Luis R. González Arestuche

    2014-01-01

    Full Text Available Esta investigación recopila en documento único, el mejor quehacer de uno de los principales forjadores de Matanzas como ciudad y del desarrollo industrial inicial, alcanzado en el siglo XIX, para la demarcación. El respeto hacia la conservación y el rescate del patrimonio construido en la actual provincia homónima, por sus altísimos valores: histórico, cultural y tecnológico, considera la necesidad del conocimiento ciudadano sobre la actividad del francés Jules Sagebien Tavernier. Desde el año 2009 diferentes instituciones y asociaciones promueven, desde Francia y aquí en Cuba, el estudio de sus realizaciones. Este trabajo pretende ir más allá de las observaciones anteriores, ya que los autores logran crear un catálogo, referido a la ingeniería de puentes desarrollada por él, que tuvo su máxima expresión en la propia ciudad de Matanzas y en los diferentes ramales ferroviarios que diseñó; obras todas ejecutadas en un tiempo que hoy parece imposible de alcanzar.

  7. Jules Tinel (1879-1952): Beyond the eponym, the man and his forgotten neurological contributions.

    Science.gov (United States)

    Walusinski, O

    2017-06-01

    The trauma of World War I had a lasting impact on clinician and physiologist Jules Tinel (1879-1952). His treatment of peripheral nervous system injuries led him, in 1917, to describe the eponymous sign that he linked to activity of the sympathetic nervous system. Among the sequelae of nerve injuries, he was confronted with causalgia that he attributed, here again, to the autonomic nervous system, the main focus of his laboratory research throughout his career. Tinel's sign became so well known that it eclipsed the originality of his seminal descriptions of exertional headache and of hypertensive emergency caused by pheochromocytoma, which could also have been associated with his name. He was always able to marry his clinical practice of neurology and psychiatric consultations with his anatomicopathological, physiological and pathophysiological research, which was based on his daily practice as a physician. At the same time, he directed the work of numerous assistants in his research laboratory, which has since been unjustly forgotten. Several hundreds of scientific publications, including three seminal works, bear witness to his intense activity, which he combined with a genuine talent for teaching and making his findings accessible to a wider public. Those publications alone would fully justify the historical value of extending his renown beyond the existing eponym. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  8. Radiation Transport Calculation of the UGXR Collimators for the Jules Horowitz Reactor (JHR)

    Science.gov (United States)

    Chento, Yelko; Hueso, César; Zamora, Imanol; Fabbri, Marco; Fuente, Cristina De La; Larringan, Asier

    2017-09-01

    Jules Horowitz Reactor (JHR), a major infrastructure of European interest in the fission domain, will be built and operated in the framework of an international cooperation, including the development and qualification of materials and nuclear fuel used in nuclear industry. For this purpose UGXR Collimators, two multi slit gamma and X-ray collimation mechatronic systems, will be installed at the JHR pool and at the Irradiated Components Storage pool. Expected amounts of radiation produced by the spent fuel and X-ray accelerator implies diverse aspects need to be verified to ensure adequate radiological zoning and personnel radiation protection. A computational methodology was devised to validate the Collimators design by means of coupling different engineering codes. In summary, several assessments were performed by means of MCNP5v1.60 to fulfil all the radiological requirements in Nominal scenario (TEDE < 25µSv/h) and in Maintenance scenario (TEDE < 2mSv/h) among others, detailing the methodology, hypotheses and assumptions employed.

  9. Jules Horowitz Reactor, a new irradiation facility: Improving dosimetry for the future of nuclear experimentation

    Energy Technology Data Exchange (ETDEWEB)

    Gregoire, G.; Beretz, D.; Destouches, C. [CEA, DEN, DER/SPEX, F-13108 Saint-Paul-lez-Durance (France)

    2011-07-01

    Document available in abstract form only, full text of document follows: The Jules Horowitz Reactor (JHR) is an experimental reactor under construction at the French Nuclear Energy and Alternative Energies Commission (CEA) facility at Cadarache. It will achieve its first criticality by the end of 2014. Experiments that will be conducted at JHR will deal with fuel, cladding, and material behavior. The JHR will also produce medical radio-isotopes and doped silicon for the electronic industry. As a new irradiation facility, its instrumentation will benefit from recent improvements. Nuclear instrumentation will include reactor dosimetry, as it is a reference technique to determine neutron fluence in experimental devices or characterize irradiation locations. Reactor dosimetry has been improved with the progress of simulation tools and nuclear data, but at the same time the customer needs have increased: Experimental results must have reduced and assessed uncertainties. This is now a necessary condition to perform an experimental irradiation in a test reactor. Items improved, in the framework of a general upgrading of the dosimetry process based on uncertainty minimization, will include dosimeter, nuclear data, and modelling scheme. (authors)

  10. Love stories can be unpredictable: Jules et Jim in the vortex of life

    Science.gov (United States)

    Dercole, Fabio; Rinaldi, Sergio

    2014-06-01

    Love stories are dynamic processes that begin, develop, and often stay for a relatively long time in a stationary or fluctuating regime, before possibly fading. Although they are, undoubtedly, the most important dynamic process in our life, they have only recently been cast in the formal frame of dynamical systems theory. In particular, why it is so difficult to predict the evolution of sentimental relationships continues to be largely unexplained. A common reason for this is that love stories reflect the turbulence of the surrounding social environment. But we can also imagine that the interplay of the characters involved contributes to make the story unpredictable—that is, chaotic. In other words, we conjecture that sentimental chaos can have a relevant endogenous origin. To support this intriguing conjecture, we mimic a real and well-documented love story with a mathematical model in which the environment is kept constant, and show that the model is chaotic. The case we analyze is the triangle described in Jules et Jim, an autobiographic novel by Henri-Pierre Roché that became famous worldwide after the success of the homonymous film directed by François Truffaut.

  11. Radiation Transport Calculation of the UGXR Collimators for the Jules Horowitz Reactor (JHR

    Directory of Open Access Journals (Sweden)

    Chento Yelko

    2017-01-01

    Full Text Available Jules Horowitz Reactor (JHR, a major infrastructure of European interest in the fission domain, will be built and operated in the framework of an international cooperation, including the development and qualification of materials and nuclear fuel used in nuclear industry. For this purpose UGXR Collimators, two multi slit gamma and X-ray collimation mechatronic systems, will be installed at the JHR pool and at the Irradiated Components Storage pool. Expected amounts of radiation produced by the spent fuel and X-ray accelerator implies diverse aspects need to be verified to ensure adequate radiological zoning and personnel radiation protection. A computational methodology was devised to validate the Collimators design by means of coupling different engineering codes. In summary, several assessments were performed by means of MCNP5v1.60 to fulfil all the radiological requirements in Nominal scenario (TEDE < 25µSv/h and in Maintenance scenario (TEDE < 2mSv/h among others, detailing the methodology, hypotheses and assumptions employed.

  12. Coupling between the JULES land-surface scheme and the CCATT-BRAMS atmospheric chemistry model (JULES-CCATT-BRAMS1.0): applications to numerical weather forecasting and the CO2 budget in South America

    Science.gov (United States)

    Moreira, D. S.; Freitas, S. R.; Bonatti, J. P.; Mercado, L. M.; Rosário, N. M. É.; Longo, K. M.; Miller, J. B.; Gloor, M.; Gatti, L. V.

    2013-01-01

    This article presents the development of a new numerical system denominated JULES-CCATT-BRAMS, which resulted from the coupling of the JULES surface model to the CCATT-BRAMS atmospheric chemistry model. The performance of this system in relation to several meteorological variables (wind speed at 10 m, air temperature at 2 m, dew point temperature at 2 m, pressure reduced to mean sea level and 6 h accumulated precipitation) and the CO2 concentration above an extensive area of South America is also presented, focusing on the Amazon basin. The evaluations were conducted for two periods, the wet (March) and dry (September) seasons of 2010. The statistics used to perform the evaluation included bias (BIAS) and root mean squared error (RMSE). The errors were calculated in relation to observations at conventional stations in airports and automatic stations. In addition, CO2 concentrations in the first model level were compared with meteorological tower measurements and vertical CO2 profiles were compared with aircraft data. The results of this study show that the JULES model coupled to CCATT-BRAMS provided a significant gain in performance in the evaluated atmospheric fields relative to those simulated by the LEAF (version 3) surface model originally utilized by CCATT-BRAMS. Simulations of CO2 concentrations in Amazonia and a comparison with observations are also discussed and show that the system presents a gain in performance relative to previous studies. Finally, we discuss a wide range of numerical studies integrating coupled atmospheric, land surface and chemistry processes that could be produced with the system described here. Therefore, this work presents to the scientific community a free tool, with good performance in relation to the observed data and re-analyses, able to produce atmospheric simulations/forecasts at different resolutions, for any period of time and in any region of the globe.

  13. Coupling between the JULES land-surface scheme and the CCATT-BRAMS atmospheric chemistry model (JULES-CCATT-BRAMS1.0: applications to numerical weather forecasting and the CO2 budget in South America

    Directory of Open Access Journals (Sweden)

    D. S. Moreira

    2013-01-01

    Full Text Available This article presents the development of a new numerical system denominated JULES-CCATT-BRAMS, which resulted from the coupling of the JULES surface model to the CCATT-BRAMS atmospheric chemistry model. The performance of this system in relation to several meteorological variables (wind speed at 10 m, air temperature at 2 m, dew point temperature at 2 m, pressure reduced to mean sea level and 6 h accumulated precipitation and the CO2 concentration above an extensive area of South America is also presented, focusing on the Amazon basin. The evaluations were conducted for two periods, the wet (March and dry (September seasons of 2010. The statistics used to perform the evaluation included bias (BIAS and root mean squared error (RMSE. The errors were calculated in relation to observations at conventional stations in airports and automatic stations. In addition, CO2 concentrations in the first model level were compared with meteorological tower measurements and vertical CO2 profiles were compared with aircraft data. The results of this study show that the JULES model coupled to CCATT-BRAMS provided a significant gain in performance in the evaluated atmospheric fields relative to those simulated by the LEAF (version 3 surface model originally utilized by CCATT-BRAMS. Simulations of CO2 concentrations in Amazonia and a comparison with observations are also discussed and show that the system presents a gain in performance relative to previous studies. Finally, we discuss a wide range of numerical studies integrating coupled atmospheric, land surface and chemistry processes that could be produced with the system described here. Therefore, this work presents to the scientific community a free tool, with good performance in relation to the observed data and re-analyses, able to produce atmospheric simulations/forecasts at different resolutions, for any period of time and in any region of the globe.

  14. Evaluation of the JULES land surface model in simulating catchment hydrology in Southern Africa

    Directory of Open Access Journals (Sweden)

    N. C. MacKellar

    2013-08-01

    Full Text Available Land surface models (LSMs are advanced tools which can be used to estimate energy, water and biogeochemical exchanges at regional scales. The inclusion of a river flow routing module in an LSM allows for the simulation of river discharge from a catchment and offers an approach to evaluate the response of the system to variations in climate and land-use, which can provide useful information for regional water resource management. This study offers insight into some of the pragmatic considerations of applying an LSM over a regional domain in Southern Africa. The objectives are to identify key parameter sensitivities and investigate differences between two runoff production schemes in physically contrasted catchments. The Joint UK Land Environment Simulator (JULES LSM was configured for a domain covering Southern Africa at a 0.5° resolution. The model was forced with meteorological input from the WATCH Forcing Data for the period 1981–2001 and sensitivity to various model configurations and parameter settings were tested. Both the PDM and TOPMODEL sub-grid scale runoff generation schemes were tested for parameter sensitivities, with the evaluation focussing on simulated river discharge in sub-catchments of the Orange, Okavango and Zambezi rivers. It was found that three catchments respond differently to the model configurations and there is no single runoff parameterization scheme or parameter values that yield optimal results across all catchments. The PDM scheme performs well in the upper Orange catchment, but poorly in the Okavango and Zambezi, whereas TOPMODEL grossly underestimates discharge in the upper Orange and shows marked improvement over PDM for the Okavango and Zambezi. A major shortcoming of PDM is that it does not realistically represent subsurface runoff in the deep, porous soils typical of the Okavango and Zambezi headwaters. The dry-season discharge in these catchments is therefore not replicated by PDM. TOPMODEL, however

  15. The Jules Horowitz reactor (JHR), a European material testing reactor (MTR), with extended experimental capabilities

    Energy Technology Data Exchange (ETDEWEB)

    Ballagny, A.; Bergamaschi, Y.; Bouilloux, Y.; Bravo, X.; Guigon, B.; Rommens, M.; Tremodeux, P. [CEA Cadarache, Dir. de l' Energie Nucleaire DEN, 13 - Saint-Paul-lez-Durance (France)]|[CEA Saclay Dir. de l' Energie Nucleaire DEN, 91 - Gif sur Yvette (France)

    2003-07-01

    The Jules Horowitz Reactor (JHR) is the European MTR (Material Testing Reactor) designed to provide, after 2010, the necessary knowledge for keeping the existing power plants in operation and to design innovative reactors types with new objectives such as: minimizing the radioactive waste production, taking into account additional safety requirements, preventing risks of nuclear proliferation... To achieve such an ambitious objective. The JHR is designed with a high flexibility in order to satisfy the current demand from European industry, research and to be able to accommodate future requirements. The JHR will offer a wide range of performances and services in gathering, in a single site at Cadarache, all the necessary functionalities and facilities for an effective production of results: e.g. fuel fabrication laboratories, preparation of the instrumented devices, interpretation of the experiments, modelling. The JHR must rely on a top level scientific environment based on experts teams from CEA and EC and local universities. With a thermal flux of 7,4.10{sup 14} ncm{sup -2} s{sup -1} and a fast flux of 6,4.10{sup 14} ncm{sup -2}s{sup -1}, it is possible to carry out irradiation experiments on materials and fuels whatever the reactor type considered. It will also be possible to carry out locally, fast neutron irradiation to achieve damage effect up to 25 dpa/year. (dpa = displacement per atom.) The study of the fuels behavior under accidental conditions, from analytical experiments, on a limited amount of irradiated fuel, is a major objective of the project. These oriented safety tests are possible by taking into account specific requirements in the design of the facility such as the tightness level of the containment building, the addition of an alpha hot cell and a laboratory for on line fission products measurement. (authors)

  16. The Jules Horowitz reactor (JHR), a European material testing reactor (MTR), with extended experimental capabilities

    Energy Technology Data Exchange (ETDEWEB)

    Ballagny, A.; Bergamaschi, Y.; Bouilloux, Y.; Bravo, X.; Guigon, B.; Rommens, M.; Tremodeux, P. [CEA Cadarache, Dir. de l' Energie Nucleaire DEN, 13 - Saint-Paul-lez-Durance (France)]|[CEA Saclay Dir. de l' Energie Nucleaire DEN, 91 - Gif sur Yvette (France)

    2003-07-01

    The Jules Horowitz Reactor (JHR) is the European MTR (Material Testing Reactor) designed to provide, after 2010, the necessary knowledge for keeping the existing power plants in operation and to design innovative reactors types with new objectives such as: minimizing the radioactive waste production, taking into account additional safety requirements, preventing risks of nuclear proliferation... To achieve such an ambitious objective. The JHR is designed with a high flexibility in order to satisfy the current demand from European industry, research and to be able to accommodate future requirements. The JHR will offer a wide range of performances and services in gathering, in a single site at Cadarache, all the necessary functionalities and facilities for an effective production of results: e.g. fuel fabrication laboratories, preparation of the instrumented devices, interpretation of the experiments, modelling. The JHR must rely on a top level scientific environment based on experts teams from CEA and EC and local universities. With a thermal flux of 7,4.10{sup 14} ncm{sup -2} s{sup -1} and a fast flux of 6,4.10{sup 14} ncm{sup -2}s{sup -1}, it is possible to carry out irradiation experiments on materials and fuels whatever the reactor type considered. It will also be possible to carry out locally, fast neutron irradiation to achieve damage effect up to 25 dpa/year. (dpa = displacement per atom.) The study of the fuels behavior under accidental conditions, from analytical experiments, on a limited amount of irradiated fuel, is a major objective of the project. These oriented safety tests are possible by taking into account specific requirements in the design of the facility such as the tightness level of the containment building, the addition of an alpha hot cell and a laboratory for on line fission products measurement. (authors)

  17. D'Elisée Reclus à Jules Verne. Aux origines de la géographie dans les Voyages Extraordinaires.

    OpenAIRE

    Dupuy, Lionel

    2006-01-01

    Les Voyages Extraordinaires de Jules Verne témoignent de nombreux emprunts aux ouvrages du géographe français Elisée Reclus, au premier rang desquels figure sa monumentale Nouvelle Géographie Universelle. Il est intéressant de remarquer que les références directes a Elisée Reclus dans les romans de Jules Verne datent toutes d'après 1885, un tournant majeur dans la production vernienne.

  18. Analysis of Media Stereotypes of the Russian Image in Media Studies in the Student Audience (example: the screen versions of Jules Verne's Novel “Michael Strogoff”

    Directory of Open Access Journals (Sweden)

    Alexander Fedorov

    2014-09-01

    Full Text Available As a result of the analysis students come to the conclusion that the screen adaptations of Jules Verne's novel ''Michael Strogoff'' create, though an oversimplified and adapted to western stereotypes of perception, but a positive image of Russia – as a stronghold of European values at the Asian frontiers, a country with a severe climate, boundless Siberian spacious areas, manly and patriotic warriors, a wise monarchy. At the same time, both Jules Verne's novel and its screen adaptations contain clear-cut western pragmatism – the confidence that if a man has a proper will he can rule his destiny.

  19. Vamos ao Brasil com Jules Verne?: processos editoriais e civilização nas Voyages Extraordinaires

    Directory of Open Access Journals (Sweden)

    Andréa Borges Leão

    2012-12-01

    Full Text Available No século XIX, uma rede de conhecimentos sobre as diferenças culturais dos povos americanos marcou a edição destinada à instrução e diversão da juventude francesa. Uma das 62 Voyages Extraordinaires de Jules Verne, publicadas por Pierre-Jules Hetzel, é ambientada entre o Peru e o Brasil: La Jangada, huit cents lieues sur l'Amazone (1881. Na produção de literatura juvenil que se desenvolve e expande no comércio transatlântico da livraria francesa, sobressai uma psicogênese do Brasil. Por esse ângulo, a via de análise aberta pelo sociólogo Norbert Elias ajudou a enfrentar o problema das emoções humanas, no romance de viagem, e a conceituar a atividade mimética no livro de ciência e recreação.

  20. Main technical options of the Jules Horowitz reactor project to achieve high flux performances and high safety level

    Energy Technology Data Exchange (ETDEWEB)

    Ballagny, A.; Bergamaschi, Y.; Bouilloux, Y.; Bravo, X.; Guigon, B.; Rommens, M.; Tremodeux, P. [CEA Cadarache, Dir. de l' Energie Nucleaire DEN, 13 - Saint-Paul-lez-Durance (France)]|[CEA Saclay Dir. de l' Energie Nucleaire DEN, 91 - Gif sur Yvette (France)

    2003-07-01

    Since the shutdown of the SILOE reactor in 1997, the OSIRIS reactor has ensured the needs regarding technological irradiation at CEA including those of its industrial partners and customers. The Jules Horowitz Reactor will replace it and will offer a quite larger experimental field. It has the ambition to provide the necessary nuclear data and to maintain a fission research capability in Europe after 2010. The Jules Horowitz Reactor will represent a significant step in terms of performances and experimental capabilities. This paper will present the main design option resulting from the preliminary studies. The choice of the specific power around 600 kW/I for the reference core configuration is a key decision to ensure the required flux level. Consequently many choices have to be made regarding the materials used in the core and the fuel element design. These involve many specific qualifications including codes validation. The main safety options are based on: - A safety approach based upon the defence-in-depth principle. - A strategy of generic approaches to assess experimental risks in the facility. - Internal events analysis taking into account risks linked to reactor and experiments (e.g., radioactive source-term). - Systematic consideration of external hazards (e.g., earthquake, airplane crash) and internal hazards. - Design of containment to manage and mitigate a severe reactor accident (consideration of 'BORAX' accident, according to french safety practice for MTRs, beyond design basis reactivity insertion accident, involving core melting and core destruction phenomena). (authors)

  1. Improved representation of plant functional types and physiology in the Joint UK Land Environment Simulator (JULES v4.2) using plant trait information

    NARCIS (Netherlands)

    Harper, Anna B.; Cox, Peter M.; Friedlingstein, Pierre; Wiltshire, Andy J.; Jones, Chris D.; Sitch, Stephen; Mercado, Lina M.; Groenendijk, Margriet; Robertson, Eddy; Kattge, Jens; Bönisch, Gerhard; Atkin, Owen K.; Bahn, Michael; Cornelissen, Johannes; Niinemets, Ülo; Onipchenko, Vladimir; Peñuelas, Josep; Poorter, Lourens; Reich, Peter B.; Soudzilovskaia, Nadjeda A.; Bodegom, van Peter

    2016-01-01

    Dynamic global vegetation models are used to predict the response of vegetation to climate change. They are essential for planning ecosystem management, understanding carbon cycle-climate feedbacks, and evaluating the potential impacts of climate change on global ecosystems. JULES (the Joint UK

  2. Improved representation of plant functional types and physiology in the Joint UK Land Environment Simulator (JULES v4.2) using plant trait information

    NARCIS (Netherlands)

    Harper, Anna B.; Cox, Peter M.; Friedlingstein, Pierre; Wiltshire, Andy J.; Jones, Chris D.; Sitch, Stephen; Mercado, Lina M.; Groenendijk, Margriet; Robertson, Eddy; Kattge, Jens; Bönisch, Gerhard; Atkin, Owen K.; Bahn, Michael; Cornelissen, Johannes; Niinemets, Ülo; Onipchenko, Vladimir; Peñuelas, Josep; Poorter, Lourens; Reich, Peter B.; Soudzilovskaia, Nadjeda A.; Bodegom, van Peter

    2016-01-01

    Dynamic global vegetation models are used to predict the response of vegetation to climate change. They are essential for planning ecosystem management, understanding carbon cycle-climate feedbacks, and evaluating the potential impacts of climate change on global ecosystems. JULES (the Joint UK L

  3. Jules Verne, le Québec et le Canada. Variations sur la géographie et l'écologie humaine dans trois romans canadiens de Jules Verne.

    OpenAIRE

    Dupuy, Lionel

    2009-01-01

    La géographie est au cœur des récits verniens, elle en est la pierre angulaire. Nous avions à ce titre présenté dans un article précédent comment la géographie, en particulier dans les romans de Jules Verne, peut être abordée également dans sa dimension imaginaire, symbolique, mystérieuse. Nous aimerions ainsi, dans ce nouvel article, souligner comment cette dernière sert aussi de base à l'élaboration de ce que nous pouvons appeler aujourd'hui une écologie humaine des Voyages Extraordinaires....

  4. Corrosion of the AlFeNi alloy used for the fuel cladding in the Jules Horowitz research reactor

    Science.gov (United States)

    Wintergerst, M.; Dacheux, N.; Datcharry, F.; Herms, E.; Kapusta, B.

    2009-09-01

    The AlFeNi aluminium alloy (1 wt% Fe, 1 wt% Ni, 1 wt% Mg) is expected to be used as nuclear fuel cladding for the Jules Horowitz experimental reactor. To guarantee a safe behaviour of the fuel, a good understanding of the fuel clad corrosion mechanisms is required. In this field, the experimental characterization of the selected alloy was performed. Then experimental studies of the aluminium alloy corrosion product obtained in autoclaves have shown an oxide film composed of two layers. This duplex structure results from a mixed growth mechanism: an anionic growth to develop the inner oxide and a cationic diffusion parallel to a dissolution-precipitation process to form the outer zone. Dynamic experiments at 70 °C have demonstrated that a solid diffusion step controls the release kinetic. Then post-irradiation exams performed on irradiated fuel plates were used to investigate the effects of the irradiation on the corrosion behaviour in the reactor core.

  5. La géographie de Jules Verne et ses cartes dans L’île mystérieuse

    Directory of Open Access Journals (Sweden)

    Jacky Fontanabona

    2010-05-01

    Full Text Available Destinés à la jeunesse, les Voyages extraordinaires ont une vocation récréative mais aussi éducative. Romancier, Jules Verne veut aussi contribuer à la diffusion d'une géographie de son temps, descriptive, encyclopédique, de plain-pied dans une réalité constituée de «faits avérés». Dans L’île mystérieuse, il subvertit cette dernière règle en narrant la colonisation d’un territoire fictif par des Robinsons. Articulant carte, images et texte littéraire, l'édition illustrée devient alors un système d’expression qui joue du diptyque véracité/véridicité pour inventer une chimère géographique.

  6. Emission and transmission tomography systems to be developed for the future needs of Jules Horowitz material testing reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kotiluoto, Petri [VTT Technical Research Centre of Finland, P.O.Box 1000, FI-02044 VTT (Finland)], E-mail: petri.kotiluoto@vtt.fi; Wasastjerna, Frej; Kekki, Tommi [VTT Technical Research Centre of Finland, P.O.Box 1000, FI-02044 VTT (Finland); Sipilae, Heikki; Banzuzi, Kukka [Oxford Instruments Analytical Oy, Nihtisillankuja 5, P.O.Box 85, FI-02631 Espoo (Finland); Kinnunen, Petri; Heikinheimo, Liisa [VTT Technical Research Centre of Finland, P.O.Box 1000, FI-02044 VTT (Finland)

    2009-08-01

    The new 100 MW Jules Horowitz material testing reactor will be built in Cadarache, France. It will support, for instance, research on new types of innovative nuclear fuel. As a Finnish in-kind contribution, 3D emission and transmission tomography equipment will be delivered for both the reactor and the active component storage pool. The image reconstruction of activities inside the used nuclear fuel will be based on gamma spectrometry measurements. A new type of underwater digital X-ray linear detector array is under development for transmission imaging, based on GaAs and direct conversion of X-rays into an electrical signal. A shared collimator will be used for both emission and transmission measurements. Some preliminary design has been performed. For the current design, the expected gamma spectrometric response of a typical high-purity germanium detector has been simulated with MCNP for minimum and maximum source activities (specified by CEA) to be measured in future.

  7. Sensitivity Analysis and Parameter Identifiability of the Land Surface Model JULES at the point scale in permeable catchments

    Science.gov (United States)

    Bakopoulou, C.; Bulygina, N.; Butler, A. P.; McIntyre, N. R.

    2012-04-01

    Land surface models (LSMs) are recognised as important components of Global Circulation Models (GCMs). Simulating exchanges of the moisture, carbon and energy between land surface and atmosphere in a consistent manner requires physics-based LSMs of high complexity, fine vertical resolution and a large number of parameters that need to be estimated. The "physics" that is incorporated in such models is generally based on our knowledge of point (or very small) scale hydrological processes. Therefore, while larger GCM grid-scale performance may be the ultimate goal, the ability of the model to simulate the point-scale processes is, intuitively, a pre-requisite for its reliable use at larger scales. Critical evaluation of model performance and parameter uncertainty at point scales is therefore a rational starting point for critical evaluation of LSMs; and identification of optimal parameter sets at the point scale is a significant stage of the model evaluation at larger scales. The Joint UK Land Environment Simulator (JULES) is a complex LSM, which is used to represent surface exchanges in the UK Met Office's forecast and climate change models. This complexity necessitates a large number of model parameters (in total 108) some of which are incapable of being measured directly at large (i.e. kilometer) scales. For this reason, a parameter sensitivity analysis is a vital confidence building process within the framework of every LSM, and as a part of the calibration strategy. The problem of JULES parameter estimation and uncertainty at the point scale with a view to assessing the accuracy and the uncertainty in the default parameter values is addressed. The sensitivity of the JULES output of soil moisture is examined using parameter response surface analysis. The implemented technique is based on the Regional Sensitivity Analysis method (RSA), which evaluates the model response surface over a region of parameter space using Monte Carlo sampling. The modified version of RSA

  8. [The amazing career of a homeopath, philanthropist, Fourierist, Benoît-Jules Mure. (1809-1858)].

    Science.gov (United States)

    Ségal, Alain; Trépardoux, Francis

    2005-01-01

    The authors evoke the difficulty of dealing with the life and work of Benoît-Jules Mure who was a homeopathic scientist and a keen specialist on propaganda. He was also an adept of Charles Fourier and he used almost his fortune to the spreading of homeopathy and at time, the improvement of social life. Thus he tried to settle humanitarian colonies in Brazil and later in Egypt, Nubian and Sudan in order to improve their fashion of life. He was hit by tuberculosis which led him discover homeopathy and by his strength of character lie led the idea of his mission in favour of his convictions. He was very angry with the official medical organisation and at last he never has been recognized as a médical doctor. The authors underline that his life and his work have probably left some definite marks in the South America let alone the birth of Socialism.

  9. Jules Verne, Le Superbe Orénoque et la géophagie. L'intertextualité au service de l'exotisme géographique.

    OpenAIRE

    Dupuy, Lionel

    2009-01-01

    L'exégèse de l'œuvre de Jules Verne ouvre parfois la voie à des interprétations très inattendues. Tel est ainsi l'exemple de la géophagie que l'auteur évoque dans quelques-uns de ses romans, et plus particulièrement dans Le Superbe Orénoque (1898). Si pour certains auteurs Jules Verne fait directement écho ici à ses propres ennuis gastriques, nous voudrions cependant rappeler les sources qu'il a utilisées pour écrire son roman. Sans renier pour autant l'interprétation qui est proposée par ces...

  10. La "Carta a los maestros" de Jules Ferry (1883 y el laicismo escolar de la IIIª República francesa

    Directory of Open Access Journals (Sweden)

    Juan Manuel FERNÁNDEZ SORIA

    2010-03-01

    Full Text Available RESUMEN: Partiendo del valor histórico —de lo que es una muestra su influencia en la política educativa de la Segunda República española— y de la proyección de su legado en nuestros días de la «Carta a los Maestros» (1883 del ministro francés de Instrucción Pública, Jules Ferry, este trabajo se acerca a la vida de su autor y a su política educativa para analizar luego con mayor profundidad los aspectos más sobresalientes del documento —que transcribimos en francés y castellano—, especialmente el laicismo escolar, como medio de establecer una escuela nacional y de fundación de la República, la defensa de la moral común y positiva, los modos y procedimientos —tanto directos como indirectos— de su enseñanza, así como el papel del maestro y del manual en la educación moral y cívica del futuro ciudadano. ABSTRACT: Starting with the historic value —of which it is an example its influence in the educational policy of the Second Republic— and with the influence that remains in our days, of the legate of the «Elementary Schoolteacher’s Letter», written by Jules Ferry, French minister of the Public Instruction, this piece of work approaches to its author’s life and to its educational policy in order to analyse later in greater detail the most relevant aspects of the document —which we reproduce in Spanish and French— specially the scholastic laicism as a way to establish a national school, and the foundation of the Republic, the defence of common and positive morality, the ways and procedures, both direct and indirect, of its teaching, and also the role of schoolteachers and the guide in the moral and civic education of the future citizens.

  11. Further evaluation of wetland emission estimates from the JULES land surface model using SCIAMACHY and GOSAT atmospheric column methane measurements

    Science.gov (United States)

    Hayman, Garry; Comyn-Platt, Edward; McNorton, Joey; Chipperfield, Martyn; Gedney, Nicola

    2016-04-01

    The atmospheric concentration of methane began rising again in 2007 after a period of near-zero growth [1,2], with the largest increases observed over polar northern latitudes and the Southern Hemisphere in 2007 and in the tropics since then. The observed inter-annual variability in atmospheric methane concentrations and the associated changes in growth rates have variously been attributed to changes in different methane sources and sinks [2,3]. Wetlands are generally accepted as being the largest, but least well quantified, single natural source of CH4, with global emission estimates ranging from 142-284 Tg yr-1 [3]. The modelling of wetlands and their associated emissions of CH4 has become the subject of much current interest [4]. We have previously used the HadGEM2 chemistry-climate model to evaluate the wetland emission estimates derived using the UK community land surface model (JULES, the Joint UK Land Earth Simulator) against atmospheric observations of methane, including SCIAMACHY total methane columns [5] up to 2007. We have undertaken a series of new HadGEM2 runs using new JULES emission estimates extended in time to the end of 2012, thereby allowing comparison with both SCIAMACHY and GOSAT atmospheric column methane measurements. We will describe the results of these runs and the implications for methane wetland emissions. References [1] Rigby, M., et al.: Renewed growth of atmospheric methane. Geophys. Res. Lett., 35, L22805, 2008; [2] Nisbet, E.G., et al.: Methane on the Rise-Again, Science 343, 493, 2014; [3] Kirschke, S., et al.,: Three decades of global methane sources and sinks, Nature Geosciences, 6, 813-823, 2013; [4] Melton, J. R., et al.: Present state of global wetland extent and wetland methane modelling: conclusions from a model inter-comparison project (WETCHIMP), Biogeosciences, 10, 753-788, 2013; [5] Hayman, G.D., et al.: Comparison of the HadGEM2 climate-chemistry model against in situ and SCIAMACHY atmospheric methane data, Atmos. Chem

  12. The dependence of land-atmosphere interactions on atmospheric parametrizations in the JULES/UM modelling system

    Science.gov (United States)

    Johnson, Helen; Best, Martin

    2015-04-01

    It has been understood for a while now that atmospheric behaviour is affected by land surface processes, modelling this relationship however still presents challenges. Most numerical weather prediction (NWP) models couple an atmospheric model to a land surface model in order to forecast the weather and/or climate. The Global Land-Atmosphere Coupling Experiment (GLACE) demonstrated that soil moisture variability has considerable control over atmospheric behaviour, particularly impacting on precipitation and temperature variability. The study also suggested that differences in coupling strengths between models may be due to differences in atmospheric parametrizations. There have since been other studies which support this claim but it is not yet clear which parameters control the land-atmosphere coupling strength or indeed what it should be. In this study we investigate whether certain atmospheric parameters hold more control than others over model sensitivity to land surface changes. We focus on the interaction of the JULES (Joint UK Land Environment Simulator) land surface model with the Met Office Unified Model (UM) that is used for operational NWP and climate prediction. For computational efficiency we ran the UM at a single site using a single column model (SCM) rather than running a global model simulation. A site in the Sahel region of West Africa was chosen as this is an area that was identified by GLACE as being especially responsive to changes in soil moisture. JULES was run several times with various different initial soil moisture profiles to create an ensemble of surface sensible and latent heat fluxes that could be used to force a set of different SCM runs in order to simulate a range of different atmospheric conditions. Various atmospheric parameters in the SCM were then perturbed to create additional sets of SCM runs with different sensitivities to soil moisture changes. By analysing the difference in spread between the standard configuration and the

  13. Improved representation of plant functional types and physiology in the Joint UK Land Environment Simulator (JULES v4.2) using plant trait information

    Science.gov (United States)

    Harper, Anna B.; Cox, Peter M.; Friedlingstein, Pierre; Wiltshire, Andy J.; Jones, Chris D.; Sitch, Stephen; Mercado, Lina M.; Groenendijk, Margriet; Robertson, Eddy; Kattge, Jens; Bönisch, Gerhard; Atkin, Owen K.; Bahn, Michael; Cornelissen, Johannes; Niinemets, Ülo; Onipchenko, Vladimir; Peñuelas, Josep; Poorter, Lourens; Reich, Peter B.; Soudzilovskaia, Nadjeda A.; van Bodegom, Peter

    2016-07-01

    Dynamic global vegetation models are used to predict the response of vegetation to climate change. They are essential for planning ecosystem management, understanding carbon cycle-climate feedbacks, and evaluating the potential impacts of climate change on global ecosystems. JULES (the Joint UK Land Environment Simulator) represents terrestrial processes in the UK Hadley Centre family of models and in the first generation UK Earth System Model. Previously, JULES represented five plant functional types (PFTs): broadleaf trees, needle-leaf trees, C3 and C4 grasses, and shrubs. This study addresses three developments in JULES. First, trees and shrubs were split into deciduous and evergreen PFTs to better represent the range of leaf life spans and metabolic capacities that exists in nature. Second, we distinguished between temperate and tropical broadleaf evergreen trees. These first two changes result in a new set of nine PFTs: tropical and temperate broadleaf evergreen trees, broadleaf deciduous trees, needle-leaf evergreen and deciduous trees, C3 and C4 grasses, and evergreen and deciduous shrubs. Third, using data from the TRY database, we updated the relationship between leaf nitrogen and the maximum rate of carboxylation of Rubisco (Vcmax), and updated the leaf turnover and growth rates to include a trade-off between leaf life span and leaf mass per unit area.Overall, the simulation of gross and net primary productivity (GPP and NPP, respectively) is improved with the nine PFTs when compared to FLUXNET sites, a global GPP data set based on FLUXNET, and MODIS NPP. Compared to the standard five PFTs, the new nine PFTs simulate a higher GPP and NPP, with the exception of C3 grasses in cold environments and C4 grasses that were previously over-productive. On a biome scale, GPP is improved for all eight biomes evaluated and NPP is improved for most biomes - the exceptions being the tropical forests, savannahs, and extratropical mixed forests where simulated NPP is too

  14. The Met Office Unified Model Global Atmosphere 4.0 and JULES Global Land 4.0 configurations

    Directory of Open Access Journals (Sweden)

    D. N. Walters

    2014-02-01

    Full Text Available We describe Global Atmosphere 4.0 (GA4.0 and Global Land 4.0 (GL4.0: configurations of the Met Office Unified Model and JULES (Joint UK Land Environment Simulator community land surface model developed for use in global and regional climate research and weather prediction activities. GA4.0 and GL4.0 are based on the previous GA3.0 and GL3.0 configurations, with the inclusion of developments made by the Met Office and its collaborators during its annual development cycle. This paper provides a comprehensive technical and scientific description of GA4.0 and GL4.0 as well as details of how these differ from their predecessors. We also present the results of some initial evaluations of their performance. Overall, performance is comparable with that of GA3.0/GL3.0; the updated configurations include improvements to the science of several parametrisation schemes, however, and will form a baseline for further ongoing development.

  15. The Met Office Unified Model Global Atmosphere 4.0 and JULES Global Land 4.0 configurations

    Directory of Open Access Journals (Sweden)

    D. N. Walters

    2013-05-01

    Full Text Available We describe Global Atmosphere 4.0 (GA4.0 and Global Land 4.0 (GL4.0: configurations of the Met Office Unified Model and JULES community land surface model developed for use in global and regional climate research and weather prediction activities. GA4.0 and GL4.0 are based on the previous GA3.0 and GL3.0 configurations, with the inclusion of developments made by the Met Office and its collaborators during its annual development cycle. This paper provides a comprehensive technical and scientific description of GA4.0 and GL4.0 as well as details of how these differ from their predecessors. We also present the results of some initial evaluations of their performance. These show that, overall, performance is comparable with that of GA3.0/GL3.0; the updated configurations do, however, include improvements to the science of several parametrization schemes and will form a baseline for further ongoing development.

  16. Incorporation of water vapor transfer in the JULES land surface model: Implications for key soil variables and land surface fluxes

    Science.gov (United States)

    Garcia Gonzalez, Raquel; Verhoef, Anne; Luigi Vidale, Pier; Braud, Isabelle

    2012-05-01

    This study focuses on the mechanisms underlying water and heat transfer in upper soil layers, and their effects on soil physical prognostic variables and the individual components of the energy balance. The skill of the JULES (Joint UK Environment Simulator) land surface model (LSM) to simulate key soil variables, such as soil moisture content and surface temperature, and fluxes such as evaporation, is investigated. The Richards equation for soil water transfer, as used in most LSMs, was updated by incorporating isothermal and thermal water vapor transfer. The model was tested for three sites representative of semiarid and temperate arid climates: the Jornada site (New Mexico, USA), Griffith site (Australia), and Audubon site (Arizona, USA). Water vapor flux was found to contribute significantly to the water and heat transfer in the upper soil layers. This was mainly due to isothermal vapor diffusion; thermal vapor flux also played a role at the Jornada site just after rainfall events. Inclusion of water vapor flux had an effect on the diurnal evolution of evaporation, soil moisture content, and surface temperature. The incorporation of additional processes, such as water vapor flux among others, into LSMs may improve the coupling between the upper soil layers and the atmosphere, which in turn could increase the reliability of weather and climate predictions.

  17. Jules Horowitz reactor - Complementary safety assessment in the light of the Fukushima accident; Reacteur Jules Horowitz - Evaluation complementaire de la surete au regard de l'accident survenu a la centrale nucleaire de Fukushima

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-09-13

    This CSA (Complementary Safety Assessment) analyses the robustness of the Jules Horowitz reactor (RJH) to extreme situations such as those that led to the Fukushima accident and proposes a series of improvements. RJH is being built on the Cadarache CEA's site. Robustness is the ability for the facility to withstand events beyond the level for which the facility was designed. Robustness is linked to safety margins but also to the situations leading to a sudden deterioration of the accident sequence (cliff edge effect). Safety is not only a matter of design or of engineered systems, it is also a matter of organization. So issues like RJH's crisis organization, the organization of radiation protection, and work organization via subcontracting are also taken into consideration. This report is divided into 9 main chapters: 1) main features of the RJH facility, 2) identification of cliff edge risks and of equipment essential for safety, 3) earthquake risk, 4) flood risk, 5) risks due to other extreme natural disasters, 6) the loss of electrical power supplies and of cooling systems, 7) management of severe accidents, 8) subcontracting policy, 9) synthesis and list of improvements. This study shows a globally good robustness of the RJH for the considered risks. Nevertheless it can considered relevant to increase the robustness of the plant on a few points: -) to increase the seismic safety margins of some pieces of equipment, -) to increase the robustness of the internal electrical power supplies, -) to increase the fuel cooling capacity, and -) to improve the management of the post-accidental period. (A.C.)

  18. The Jules Horowitz Reactor - A new High Performance European Material Testing Reactor open to International Users Present Status and Objectives

    Energy Technology Data Exchange (ETDEWEB)

    Iracane, Daniel; Bignan, Gilles [CEA Atomic Energy Commission Saclay Batiment 121- 91191 Gif Sur Yvette (France); Lindbaeck, Jan-Erik; Blomgren, Jan [VATTENFALL AB Nuclear Power Jaemtlandsgatan 99 SE-16287 Stockholm (Sweden)

    2010-07-01

    The development of sustainable nuclear energy requires R and D on fuel and material behaviour under irradiation with a high level of performance in order to meet the needs and challenges for the benefit of industry, research and public bodies. These stakes require a sustainable and secured access to an up-to-date high performance Material Testing Reactor. Following a broad survey within the European Research Area, the international community agreed that the need for Material Test Reactors in support of nuclear power plant safety and operation will continue in the context of sustainable nuclear energy. The Jules Horowitz Reactor project (JHR) copes with this context. JHR is designed as a user facility addressing the needs of the international community. This means: - flexibility with irradiation loops able to reproduce a large variation in operation conditions of different power reactor technologies, - high flux capacity to address Generations II, III, and IV needs. JHR is designed, built and operated as an international user facility because: - Given the maturity and globalization of the industry, domestic tools have no more the required level of economic and technical efficiency. Meanwhile, countries with nuclear energy need an access to high performance irradiation experimental capabilities to support technical skill and guarantee the competitiveness and safety of nuclear energy. - Many research items related to safety or public policy (waste management, etc.) require international cooperation to share costs and benefits of resulting consensus. JHR design is optimised for offering high performance material and fuel irradiation capability for the coming decades. This project is driven and funded by an international consortium gathering vendors, utilities and public stakeholders. This consortium has been set up in March 2007 when the construction began. The construction is in progress and the start of operation is scheduled for 2014. The JHR is a research

  19. Water Will Be the Coal of the Future—The Untamed Dream of Jules Verne for a Solar Fuel

    Directory of Open Access Journals (Sweden)

    Vladimir K. Ryabchuk

    2016-11-01

    Full Text Available This article evokes the futuristic visions of two giants, one a writer, Jules Verne, who foresaw water as the coal of the future, and the other a scientist, Giacomo Ciamician, who foresaw the utilization of solar energy as an energy source with which to drive photochemical and photocatalytic reactions for the betterment of mankind. Specifically, we examine briefly the early work of the 1960s and 1970s on the photosplitting of free water and water adsorbed on solid supports, based mostly on metal oxides, from which both hydrogen and oxygen evolve in the expected stoichiometric ratio of 2 to 1. The two oil crises of the 1970s (1973 and 1979 spurred the interest of researchers from various disciplines (photochemistry, photo-catalysis and photoelectrochemistry in search of a Holy Grail photocatalyst, process, or strategy to achieve efficient water splitting so as to provide an energy source alternative to fossil fuels. Some approaches to the photosplitting of water adsorbed on solid insulators (high bandgap materials; Ebg ≥ 5 eV and semiconductor photocatalysts (metal oxides are described from which we deduce that metal oxides with bandgap energies around 5 eV (e.g., ZrO2 are more promising materials to achieve significant water splitting on the basis of quantum yields than narrower bandgap photocatalysts (e.g., TiO2; Ebg ≈ 3.0–3.2 eV, which tend to be relatively inactive by comparison. Although proof of concept of the photosplitting of water has been demonstrated repeatedly in the last four decades, much remains to be done to find the Holy Grail photocatalyst and/or strategy to achieve significant yields of hydrogen.

  20. Water Will Be the Coal of the Future-The Untamed Dream of Jules Verne for a Solar Fuel.

    Science.gov (United States)

    Ryabchuk, Vladimir K; Kuznetsov, Vyacheslav N; Emeline, Alexei V; Artem'ev, Yurii M; Kataeva, Galina V; Horikoshi, Satoshi; Serpone, Nick

    2016-11-29

    This article evokes the futuristic visions of two giants, one a writer, Jules Verne, who foresaw water as the coal of the future, and the other a scientist, Giacomo Ciamician, who foresaw the utilization of solar energy as an energy source with which to drive photochemical and photocatalytic reactions for the betterment of mankind. Specifically, we examine briefly the early work of the 1960s and 1970s on the photosplitting of free water and water adsorbed on solid supports, based mostly on metal oxides, from which both hydrogen and oxygen evolve in the expected stoichiometric ratio of 2 to 1. The two oil crises of the 1970s (1973 and 1979) spurred the interest of researchers from various disciplines (photochemistry, photo-catalysis and photoelectrochemistry) in search of a Holy Grail photocatalyst, process, or strategy to achieve efficient water splitting so as to provide an energy source alternative to fossil fuels. Some approaches to the photosplitting of water adsorbed on solid insulators (high bandgap materials; Ebg ≥ 5 eV) and semiconductor photocatalysts (metal oxides) are described from which we deduce that metal oxides with bandgap energies around 5 eV (e.g., ZrO₂) are more promising materials to achieve significant water splitting on the basis of quantum yields than narrower bandgap photocatalysts (e.g., TiO₂; Ebg ≈ 3.0-3.2 eV), which tend to be relatively inactive by comparison. Although proof of concept of the photosplitting of water has been demonstrated repeatedly in the last four decades, much remains to be done to find the Holy Grail photocatalyst and/or strategy to achieve significant yields of hydrogen.

  1. 2nd Charles Richet et Jules Héricourt workshop: therapeutic antibodies and anaphylaxis; May 31-June 1, 2011, Tours, France.

    Science.gov (United States)

    Daguet, Arnaud; Watier, Hervé

    2011-01-01

    The Charles Richet and Jules Héricourt workshops honor the memory of Jules Héricourt (1850-1938) and Charles Richet (1850-1935) who described the principle of serotherapy in 1888 and made the very first attempts to fight cancer with serotherapy in 1895. In 1902, Charles Richet and Paul Portier described "anaphylaxis," a discovery awarded the Nobel Prize in 1913. The first workshop, "Towards the clinical use of mAbs with higher cytolytic efficacy in cancer" was held in Tours, France on November 20-21, 2008. The second Charles Richet and Jules Héricourt workshop, held May 31-June 1, 2011 at the University of Tours, France, was also organized by the Cancéropôle Grand Ouest. The topic of the workshop was therapeutic antibodies and anaphylaxis, a subject rarely addressed in congresses focused on monoclonal antibodies. To have discussions about mAb side effects with complete objectivity, the congress was organized independently of any sponsorship from pharmaceutical companies. This academic event was motivated by the high incidence of shocks to cetuximab and the need to compile and evaluate scattered information. This growing public health concern was thus analyzed from different scientific and medical angles. The first session was devoted to acute infusion reactions, with an emphasis on deconvolution of the terms "cytokine-release syndrome," "cytokine storms," "anaphylaxis" and their epidemiology. This session concluded with the Charles Richet lecture on cetuximab anaphylaxis and anti-αGal IgE by Thomas Platts-Mills, its discoverer. In the next session, the involvement of anti-glycan antibodies in both anaphylaxis and delayed hypersensitivity reactions to therapeutic antibodies was discussed. A gala dinner was held in the gardens of the beautiful château of Villandry, which was acquired and restored by Joachim Carvalho, a pupil of Charles Richet's and great-grandfather of the present owner. The final session focused on strategies to prevent cetuximab anaphylaxis

  2. Study of the uniform corrosion of an aluminium alloy used for the fuel cladding of the Jules Horowitz experimental reactor; Etude de la corrosion uniforme d'un alliage d'aluminium utilise comme gainage du combustible nucleaire du reacteur experimental Jules Horowitz

    Energy Technology Data Exchange (ETDEWEB)

    Wintergerst, M. [CEA Saclay, Dept. des Materiaux pour le Nucleaire (DEN/DANS/DMN/SEMI), 91 - Gif-sur-Yvette (France)

    2008-07-01

    For the Jules Horowitz new material testing reactor, an aluminium base alloy, AlFeNi, will be used for the cladding of the fuel plates. Taking into account the thermal properties of the alloy and of its oxide, the corrosion of the fuel cans presents many problems. The aim of this thesis is to provide a growing kinetic of the oxide layer at the surface of the AlFeNi fuel can in order to predict the life time of fuel element. Thus the mechanism of degradation of the cladding will be describe in order to integrate the different parameters of the operating reactor. (A.L.B.)

  3. Insetos em presépios e as "formigas vestidas" de Jules Martin (1832-1906: uma curiosa manufatura paulistana do final do século XIX

    Directory of Open Access Journals (Sweden)

    Dante Martins Teixeira

    2008-01-01

    Full Text Available Present in Brazil since the beginning of Portuguese colonization, crèche nativity scenes were soon adapted to local reality, a propitious circumstance for the appearance of heterodox conceptions and the use of exotic elements of the fauna and flora peculiar to each region. As records about insects are very uncommon, it is noteworthy that females of leaf-cutting ants, Atta sp. (Hymenoptera, Formicidae, were used to compose crèche nativity scenes in São Paulo State. Having subsisted at least up to the decade of 1960, the "ant crèches" of cities such as Embu das Artes could be related to the then famous "dressed ants" created by Jules Martin, a curious manufacture of the city of São Paulo in the last quarter of the 19th century.

  4. Les Deux Méthodes. Conférence par Jean Jaurès et Jules Guesde à l’Hippodrome Lillois

    OpenAIRE

    2016-01-01

    Transcription à partir de l’édition : Les Deux Méthodes. Conférence par Jean Jaurès et Jules Guesde à l’Hippodrome Lillois, Lille, Imprimerie Ouvrière P. Lagrange, 1900 (sur Gallica, reproduction de l’exemplaire coté Lb57 12889). Les numéros de pages de l’édition transcrite sont renseignés entre crochets au fil du texte ; c’est à cette pagination que se réfèrent les renvois effectués dans l’analyse du document. Nous avons remplacé « Fourrier » par « Fourier » et « Carrette » par « Carette » ;...

  5. Contribution to the determination of the neutronic parameters uncertainties of a compact heterogeneous core: the material testing Jules Horowitz reactor; Contribution a l'etude des incertitudes des parametres neutroniques d'un coeur compact et heterogene: le reacteur d'irradiation Jules Horowitz

    Energy Technology Data Exchange (ETDEWEB)

    Di Salvo, J

    2002-07-01

    The design studies of the future Material Testing Reactor Jules Horowitz require the development of an adapted neutronic calculation route. To guarantee good accuracy and save time cost, some approximations with deterministic modelling (APOLLO2 / CRONOS2) are needed. As no relevant integral experiments are yet available to ensure the accuracy of the calculation, the results need to be validated by a rigorous methodical approach, which is based on comparison against numerical benchmarks (Monte Carlo TRIPOLI4 code). In order to complete the validation results, sensitivity coefficients of main neutronic parameters to nuclear data are very useful to get an estimate of the final uncertainty on the calculation. Unfortunately, most of covariance information is missing in the recent evaluated files such as JEF-2.2. To generate missing covariance matrices, a method based on the comparison of different independent evaluations is used in this study. Special attention is paid to the determination of sensitivity coefficients, using perturbation methods and direct calculations. This study points out the importance of the non-diagonal elements of the covariance matrices as well as the neutron capture cross section uncertainty of the 27Al in the thermal range. In complement to uncertainty studies, it will be still necessary to obtain integral experimental validation of the Jules Horowitz Reactor neutronic parameters calculations. (author)

  6. La recepció de l'obra de Jules Verne pels lectors de diferents èpoques : Anàlisi de traduccions i adaptacions en català, castellà i anglès

    OpenAIRE

    Capdevila Vinaja, Marta

    2015-01-01

    Anàlisi de l'obra de Jules Verne des del punt de vista educatiu. Exposició dels seu valor educatiu en el camp de la ciència, la geografia i la història, així com també dels seus valors morals. Contradiccions entre la intenció educativa de les seves traduccions i adaptacions per a joves lectors actuals i el xoc moral que pot provocar el racisme, l'etnocentrisme i el masclisme del segle XIX, present implícitament i explícit a totes les obres de Jules Verne. Análisis de la obra de Julio Verne...

  7. Les stratégies d’insertion de l’éthique dans Le Cachet d’Onyx de Jules Barbey d’Aurevilly

    Directory of Open Access Journals (Sweden)

    Alice De Georges-Métral

    2011-01-01

    Full Text Available Barbey d’Aurevilly, qui se place sous la tutelle de Joseph de Maistre, déploie paradoxalement dans sa production romanesque toutes les nuances du thème sulfureux du plaisir de la transgression. Pontmartin stigmatise ce décalage entre la morale et le récit en reprochant à Jules Barbey d’Aurevilly de penser comme Joseph de Maistre et d’écrire comme le Marquis de Sade. Le Cachet d’Onyx, première nouvelle de Jules Barbey d’Aurevilly, écrite en 1831, est effectivement représentative de l’inscription ambivalente de la morale dans la fiction. Cette nouvelle établit des stratégies d’écriture retorses par le truchement de l’emboîtement des récits. Elle définit tout d’abord, dans le récit-cadre, une axiologie proche de ce que son auteur identifie comme une doxa, pour en révéler l’absence de fondement. La métadiégèse présente un système de valeurs inverse. Cette dissonance semble avoir pour fonction de remplacer un système évaluatif par un autre qui lui est concurrent. Or, la polyphonie des indications de lecture fournies par le narrateur, l’intertexte et le texte s’entrechoquent sans livrer de solution satisfaisante. Implicitement, c’est l’éviction de toute axiologie stable que vise la stratégie narrative du Cachet d’onyx. In his novelistic writings, Barbey d'Aurevilly, who sets himself in Joseph de Maistre's ideology, paradoxically spreads out all the nuances of the sulphurous topic of the pleasure of transgression. Pontmartin denounces this discrepancy between morality and the narrative while reproaching Jules Barbey d'Aurevilly for thinking like Joseph de Maistre and writing like the Marquis de Sade. Le cachet d'Onyx, Barbey d'Aurevilly's first short story, written in 1831, is indeed representative of the ambivalent writing of morality in fiction. This short story establishes strategies of sly style by the means of interlocking narratives. First of all, in the framework story, it defines an

  8. Inquiry in the public interest, held at Cadarache into the construction of the reactor 'Jules Horowitz' and the problems related to the public dialogue; L'enquete d'utilite publique sur la creation du 'reacteur Jules Horowitz' a Cadarache et la participation locale

    Energy Technology Data Exchange (ETDEWEB)

    Bottiglioni, F

    2007-07-15

    In this paper are presented the main points of the inquiry taken by an official board into the demand of the Cea to create a new research tool, the 'Jules Horowitz Reactor', in its research center of Cadarache. The increasing involvement of the people in the decision-making procedures dealing with important projects is summed up, so as the distinctive features of the different regulations that frame the public participation are stressed. Some improvements are suggested to carry through next inquiries faster and more easily. The participation of the public has been low: only 11 people or associations have left their remarks to the inquiry members despite the large audience that attended the different meetings and debates organized on the issue by the CNDP (national board for public debate)

  9. Evaluation of a photosynthesis-based biogenic isoprene emission scheme in JULES and simulation of isoprene emissions under present-day climate conditions

    Directory of Open Access Journals (Sweden)

    F. Pacifico

    2011-05-01

    Full Text Available We have incorporated a semi-mechanistic isoprene emission module into the JULES land-surface scheme, as a first step towards a modelling tool that can be applied for studies of vegetation – atmospheric chemistry interactions, including chemistry-climate feedbacks. Here, we evaluate the coupled model against local above-canopy isoprene emission flux measurements from six flux tower sites as well as satellite-derived estimates of isoprene emission over tropical South America and east and south Asia. The model simulates diurnal variability well: correlation coefficients are significant (at the 95 % level for all flux tower sites. The model reproduces day-to-day variability with significant correlations (at the 95 % confidence level at four of the six flux tower sites. At the UMBS site, a complete set of seasonal observations is available for two years (2000 and 2002. The model reproduces the seasonal pattern of emission during 2002, but does less well in the year 2000. The model overestimates observed emissions at all sites, which is partially because it does not include isoprene loss through the canopy. Comparison with the satellite-derived isoprene-emission estimates suggests that the model simulates the main spatial patterns, seasonal and inter-annual variability over tropical regions. The model yields a global annual isoprene emission of 535 ± 9 TgC yr−1 during the 1990s, 78 % of which from forested areas.

  10. Evaluation of a photosynthesis-based biogenic isoprene emission scheme in JULES and simulation of isoprene emissions under modern climate conditions

    Directory of Open Access Journals (Sweden)

    F. Pacifico

    2010-11-01

    Full Text Available We have incorporated a semi-mechanistic isoprene emission module into the JULES land-surface scheme. We evaluate the coupled model against local above-canopy isoprene emission flux measurements from six flux tower sites as well as satellite-derived estimates of isoprene emission over tropical South America and east and south Asia. The model simulates diurnal variability well: correlation coefficients are significant (at the 95% level for all flux tower sites. The model reproduces day-to-day variability with significant correlations (at the 95% confidence level at four of the six flux tower sites. At the UMBS site, a complete set of seasonal observations is available for two years (2000 and 2002. The model reproduces the seasonal pattern of emission during 2002, but does less well in the year 2000. Comparison with the satellite-derived isoprene-emission estimates suggests that the model simulates the main spatial patterns, seasonal and inter-annual variability over tropical regions. The model yields a global annual isoprene emission during the 1990s of 380 ± 7 TgC yr−1.

  11. Conversations avec Jules Hoüel regards sur la géométrie non euclidienne et l’analyse infinitésimale vers 1875

    CERN Document Server

    Nabonnand, Philippe

    2017-01-01

    Jules Hoüel (1823-1886) a occupé une place particulière dans les mathématiques en France durant la seconde partie du 19ème siècle. Par ses travaux de traduction et ses recensions, il a vivement contribué à la réception de la géométrie non euclidienne de Bolyai et Lobatchevski ainsi qu’aux débats sur les fondements de l’analyse. Il se situe au centre d’un vaste réseau international de correspondances en lien avec son rôle de rédacteur pour le Bulletin des sciences mathématiques et astronomiques. Cet ouvrage contient les correspondances actives et passives de Hoüel avec Joseph-Marie De Tilly, Gaston Darboux et Victor-Amédée Le Besgue ainsi qu’une introduction qui se focalise sur la découverte de l’impossibilité de démontrer le postulat des parallèles d’Euclide et l’apparition des premiers exemples de fonctions continues non dérivables.

  12. En malstrøm til begjær. Moskenesstraumen som myte og metafor hos Petter Dass, Edgar Allan Poe og Jules Verne

    Directory of Open Access Journals (Sweden)

    Even Arntzen

    2003-08-01

    Full Text Available Gjennom uminnelige tider har mennesket vært fascinert av havet. I en rekke skapelsesmyter fremstår gjerne havet som en positiv størrelse, en pulserende og livgivende urtidsstrøm. Men ved siden av å være en raus kilde til liv, er havet også nært forbundet med undergang og død,forlis og drukning. Få havstykker har som den beryktede Moskenesstraumen fått denne havets dobbelthet knyttet til seg - på den ene siden verdens største barselseng, på den annen side dødens grusomme svelg. Kanskje med unntak av Bermuda-trianglet i Sargassohavet, stedet hvor skip, og etter hvert også fly, angivelig skal ha forsvunnet sporløst i årevis, er det neppe noe havområde i verden som opp gjennom århundrene er blitt beskrevet og illustrert i tilsvarende grad som Moskenesstraumen. I denne artikkelen skal jeg rette fokus mot tre av de mange som, på høyst forskjellig vis, har latt seg fascinere og inspirere av Moskenesstraumen, nemlig Petter Dass, Edgar Allan Poeog Jules Verne.

  13. Speech by Prime Minister Francois Fillon. Visit of the Jules Horowitz experimental reactor works on the Commissariat a l'Energie et aux Energies Alternatives site. Cadarache, May 3, 2010; Discours du Premier ministre Francois FILLON Cadarache, lundi 3 mai 2010. Visite du chantier du Reacteur experimental Jules Horowitz sur le site du Commissariat a l'Energie Atomique et aux Energies Alternatives

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    In this speech, the French Prime Minister evokes the present context, the importance of strategic technologies, and the challenge of investing in these technologies within a context of reduction of public expenses. He comments the decision of his government to finance research and education activities in different domains, and more specifically in the energy sector with this fourth generation Jules Horowitz experimental reactor. He recalls that the nuclear sector has always been very important to the eyes of the successive French governments, and outlines how this reactor will contribute to reactor operational optimization, lifetime extension and safety, nuclear fuel development, etc.

  14. The Jules Horowitz reactor: complementary safety evaluation in the light of the Fukushima 1 nuclear power station accident; Reacteur Jules Horowitz evaluation complementaire de la surete au regard de l'accident servenu a la centrale nucleaire de Fukushima 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    This report proposes a complementary safety evaluation of the Jules Horowitz reactor in Cadarache (INB 172), one of the French basic nuclear installations (BNI, in French INB) in the light of the Fukushima accident. This evaluation takes the following risks into account: risks of flooding, earthquake, loss of power supply and loss of cooling, in addition to operational management of accident situations. It presents the main characteristics of the installation, identifies the risks of a cliff effect and the main structures and equipment, evaluates the seismic risk (installation sizing, installation conformity, margin evaluation), evaluates the flooding risk (installation sizing, installation conformity, margin evaluation), briefly examines other extreme natural phenomena (extreme meteorological conditions related to flooding, earthquake or flooding with a higher level than that for which the installation is designed). It analyzes the risk of a loss of power supply and of cooling (loss of external and internal electric sources, loss of the ultimate cooling system). It analyzes the management of severe accidents: crisis management organization, available intervention means, robustness of available means. It discusses the conditions of the use of subcontractors

  15. Methodological developments and qualification of calculation schemes for the modelling of photonic heating in the experimental devices of the future Jules Horowitz material testing reactor (RJH); Developpements methodologiques et qualification de schemas de calcul pour la modelisation des echauffements photoniques dans les dispositifs experimentaux du futur reacteur d'irradiation technologiques Jules Horowitz (RJH)

    Energy Technology Data Exchange (ETDEWEB)

    Blanchet, D

    2006-07-01

    The objective of this work is to develop the modelling of the nuclear heating of the experimental devices of the future Jules Horowitz material testing reactor (RJH). The strong specific nuclear power produced (460 kW/l), induces so intense photonic fluxes which cause heating and large temperature gradients that it is necessary to control it by an adequate design. However, calculations of heating are penalized by the very large uncertainties estimated at a value of about 30% (2*{sigma}) coming from the gaps and uncertainties of the data of gamma emission present in the libraries of basic nuclear data. The experimental program ADAPh aims at reducing these uncertainties. Measurements by thermoluminescent detectors (TLD) and ionisation chambers are carried out in the critical assemblies EOLE (Mox) and Minerve (UO{sub 2}). The rigorous interpretation of these measurements requires specific developments based on Monte-Carlo simulations of coupled neutron-gamma and gamma-electron transport. The developments carried out are made different in particular by the modelling of cavities phenomena and delayed gamma emissions by the decay of fission products. The comparisons calculation-measurement made it possible to identify a systematic bias confirming a tendency of calculations to underestimate measurements. A Bayesian method of adjustment was developed in order to re-estimate the principal components of the gamma heating and to transpose the results obtained to the devices of the RJH, under conditions clearly and definitely representative. This work made possible to reduce significantly the uncertainties on the determination of the gamma heating from 30 to 15 per cent. (author)

  16. ATV "Jules Verne" Tests Campaign at ESA

    Science.gov (United States)

    Pery, V.; Bouchery, J.-P.; Le Querrec, L.; Maurel, E.; Ruffino, F.

    2004-08-01

    This paper provides with an overview of the ATV first flight model tests campaign that is to take place at ESTEC Test Centre between summer 2004 and mid- 2005. The ATV vehicle mission, configuration and development logic are first briefly described. The campaign sequence and purposes are then outlined together with the main tests principles and objectives. Some of the main constraints that drive the campaign preparation and performance as well as some particular safety aspects are finally defined.

  17. Alexis Carrel: Jules Verne of cardiovascular surgery.

    Science.gov (United States)

    Friedman, S G

    1988-03-01

    There is in every field one individual who stands apart as a great thinker, leader, or teacher. In the field of cardiovascular surgery, Alexis Carrel was each of these. Proof of this lies in the fact that daily, the modern cardiovascular surgeon is likely to use a concept or technique first developed by Carrel. During the 75th anniversary year of Carrel's receipt of the Nobel Prize, the life and work of this great innovator should be remembered.

  18. 2343-IJBCS-Article-Ngueguim Jules Roger

    African Journals Online (AJOL)

    hp

    affinity with forest undergrowth such as: Tabernaemontana pachysiphon, T. crassa, Mallotus oppositifolius ..... in the under storey of pine plots is poor, this may result ... considerably limits the light that reaches the .... O'Hara K, Walters B 2006.

  19. Presentation of the Jules Horowitz reactor; Presentation du reacteur Jules Horowitz

    Energy Technology Data Exchange (ETDEWEB)

    Dupuy, J.P. [AREVA-Technicatome, 13 - Aix en Provence (France); Perotto, G. [AREVA Framatome ANP, 92 - Paris La Defense (France); Ithurrald, G. [Electricite de France (EDF), 13 - Aix en Provence (France)

    2005-07-01

    The concepts on which the RJH reactor has been designed are: -) flexibility: the reactor must be able to give experimental support to any type of reactor (light water- heavy water- gas- or molten metal-cooled power reactor); -) adaptability: RJH's operating life will be over 50 years so the reactor will have to adjust to the experimental needs that may change a lot over a so long period; -) reactor operation: RJH is optimized to produce an availability time of 275 full charge equivalent days a year; and -) costs: the minimization of experiment costs is obtained through the integration in the same facility (or located nearby on the site) of the technical means required to perform a complete experimental program from the design of the irradiation device to its recovery after irradiation and to the examination or the possible testing of the samples. Transport costs and time delays are spared. This article gives the main features of the RJH facility from the description of the building to the specificities of the reactor core. (A.C.)

  20. The astronomer Jules Janssen a globetrotter of celestial physics

    CERN Document Server

    Launay, Françoise

    2012-01-01

    Every aspect of the personality of Janssen (1824—1907) – that D’Artagnan of science, this bard of the Sun, and this audacious master builder – is covered here by Françoise Launay, his attentive and equally erudite biographer. A physicist, inventor and builder, Janssen was guided by his energy and curiosity. His research followed two directions: on the one hand the atmospheres of the Earth and the Sun, and on the other, two techniques: spectroscopy and photography. Among his numerous voyages across the globe, he went to Japan in 1874 to follow the transit of Venus in front of the Sun, the same year in which he invented his famous photographic revolver, which was, in truth, a great technical success. To observe the Sun during total eclipses he traveled to the Indies in 1868, to Oran in 1870 (escaping from besieged Paris by balloon!), returned to India in 1871, left for Siam in 1875 and, in 1883, for an island in the Pacific. One can thus understand why Henriette often complained of the solitude in whic...

  1. 1286-IJBCS-Article-André Jules Ibouda

    African Journals Online (AJOL)

    hp

    1 Université de Ouagadougou, Centre de Recherche en Sciences Biologiques Alimentaires et Nutritionnelles ... des substituts d'autres protéines (œuf par ... grand nombre de structures différentes. ... Structure et organisation de la micelle de.

  2. Historical note: Jules Séglas on language in dementia.

    Science.gov (United States)

    Obler, L K; Albert, M L

    1985-03-01

    In his book Des troubles du language chez les aliénés (1892) Séglas applied the model of language processing of his teacher, Charcot, to analyze the language disorders of various groups of mentally ill, including patients considered to suffer from dementia. Among the language phenomena he described from dementia are logorrhea, neologisms, embolalia, near-mutism, angophrasia, automatic speech, alexia, and agraphia. Séglas must be credited for his early descriptions of how language behaviors cluster in various psychiatric and dementing diseases.

  3. Chronophotography: engineer of life: Etienne-Jules Marey

    Directory of Open Access Journals (Sweden)

    Stojmenović Dragan

    2016-01-01

    Full Text Available The centre of the problem of understanding the process of movement control, incorporated in cognitive biomechanics, is theoretically determined by contemporary physiological and psychological studies, reflecting itself inevitably in cinematography. In this sense, hypothetical questions are imposed: What are the determinants of the relationship between the scientific study of the phenomenon of movement and film art? How to develop an analytical model of the body in motion diagram? What impact does a rapid movement in nature have on the development of cinematic expression? The analysis of locomotion, as a form of human biomechanical movement, leads to the construction of the necessary tool - the camera, implying the creation of scientific films, thereby raising the level of knowledge and observation of the phenomena of motion, transforming it into a contemporary aesthetical model of film art.

  4. 水电规划对四川宁南俱乐河流域两栖爬行动物的影响及对策%On Influence of Hydropower Planning on Amphibians and Reptiles in Ningnan County of Sichuan Jule River and its and Countermeasures

    Institute of Scientific and Technical Information of China (English)

    李海涛

    2012-01-01

    A survey of amphibians and reptiles of Jule River in Ningnan County, Sichuaaa Province, owing to the recently State - approved hydropower planning, by using the line statistics and data on the basis of statistics and analy- sis, has been conducted. The results show, there exist 3 sections, 14 branches, and 26 species of amphibians and rep- tiles in this area, among which amphibians are 2 sections, 9 branches, and 14 species, and reptiles 1 section, 5branches, and 12 species, with the distribution of Indomalaya and its pattern of Himalaya - Hengduan Mountains. As to the eco - characteristics of amphibians, their distribution is balanced by classifying the eco - environments as run- ning water, still water, and lands including land - running water, land -still water) ; and forest land, shrubs, grasses and farmland for reptiles, and shrubs and grasses are the major. This paper forecasts the effects of hydropower planning to amphibians and reptiles in this area. outs forward relevant countermeasures.%四川宁南县俱乐河流域近期被国家批准进行水电规划,为此我们对该流域的两栖爬行动物作了专项调查。采用线路统计法,统计与分析采集的数据。结果表明,该流域共发现两栖爬行动物3目14科26种,其中两栖类动物有2目9科14种,爬行类动物1目5科12种;该流城内两栖爬行动物均为东洋界种类的分布,分布类型以喜马拉雅一横断山区型为主。根据流域两栖类栖息的生态特点,其生态环境划分为流水、静水、陆地(含陆地一流水、陆地一静水)等,分布的种类较为均衡;爬行类栖息的生态环境划分为林地、灌草丛、田地等,其中灌草丛生态类型是该流域爬行类主要的分布区域。该文预测分析了该流域水电规划对两栖爬行动物的影响,提出了相应的保护对策。

  5. Bernard Grall, Économie de forces et production d’utilités. L’émergence du calcul économique chez les ingénieurs des Ponts et Chaussées (1831-1891, manuscrit révisé et commenté par François Vatin, Rennes, Presses universitaires de Rennes, 2004, 28 euros.Jean-Pascal Simonin, François Vatin (dir., L’œuvre multiple de Jules Dupuit (1804-1866. Calcul d’ingénieur, analyse économique et pensée sociale, Angers, Presses universitaires d’Angers, 2002, 15,25 euros.

    Directory of Open Access Journals (Sweden)

    Pierre Crépel

    2005-09-01

    Full Text Available Jules Dupuit, dont on commémore le bicentenaire en 2004, est la figure centrale de ces deux ouvrages : comme personnage étudié en tant que tel sous de multiples facettes, dans le second ; aux côtés de nombre de ses collègues de l’École des ponts et chaussées, dans le premier. Dans l’un et l’autre cas, les auteurs se penchent sur les interactions entre les activités concrètes de l’ingénieur et la construction de ses théories économiques, leurs formalisations au XIXe siècle. Les liens entre méc...

  6. Jules Verne Network: Extending and federating efforts to promote Earth sciences

    Science.gov (United States)

    Rosmorduc, V.; Bonnefond, P.; Stewart, R.

    2003-04-01

    Earth sciences are a key element of the many issues concerning the environment, natural resource management and the place of humankind on Earth today. Earth science disciplines have taken a giant leap with the emergence of space-based observation techniques, but the benefits of advances achieved have not always been felt outside specialist circles. Our aim is to develop, encourage and raise awareness of these achievements, through outreach actions and educational programs, by informing persons likely to use and exploit results, as well as decision-makers and elected representatives, and by communicating to scientists working in related disciplines. We propose, within an international framework, to bring together scientists, engineers, teachers and science communicators to raise awareness among a broad spectrum of audiences of the current state of Earth science knowledge, especially what we have learned through space-based observations. By Earth sciences we mean all sciences studying the lithosphere, oceans, atmosphere, cryosphere, biosphere and other components of our planet and the way they interact.

  7. Space Debris Conjunction Risk Assessment for the ATV-Jules Verne Mission

    Science.gov (United States)

    Delavault, S.; Dupuis, G.; Perrachon, P.

    2009-03-01

    This paper focuses on the collision risk assessment, between ATV and space debris, managed in ATV-CC at CNES during phasing to docking and de-orbit phases. First, the methods and results of middle and short term mission analyses are detailed. The effects of the two fragmentation events which occurred shortly before and after the launch (the US ASAT on USA 193 and the natural fragmentation of the Russian satellite COSMOS 2421) have been evaluated using models and data from GRAVES and USSTRATCOM catalogues. The results showed a important impact on the foreseen conjunction rate. Second, the operational procedure of the conjunction management is described. The operational organization within ATV-CC teams and with the international partners is also presented. Then, a statement of the operational conjunction management is done, showing a good consistency level with the predictions. Eventually this led to 3 avoidance events (but only one avoidance maneuver).

  8. Jules Verne's "Around the World in Eighty Days": Helping Teach the National Geography Standards

    Science.gov (United States)

    Donaldson, Daniel P.; Kuhlke, Olaf

    2009-01-01

    Consistent with developments in American education pedagogy, geography educators have made great strides exploring a wide range of high- and low-tech methods for teaching and learning geographic concepts. This article draws on a qualitative analysis of essays in which college students discuss tenets of the National Geography Standards in the…

  9. Por la liberación del niño... Jules Vallès

    Directory of Open Access Journals (Sweden)

    Manuela SAN MIGUEL

    2009-08-01

    Full Text Available Discutible es, sin duda, el valor literario intrínseco de la «novela negra» de finales del XVIII, que a menudo hacía de los niños protagonistas de terroríficos relatos, increíbles y absurdamente encadenados. Baste citar como ejemplos «Victor ou l'enfant de la forêt» y «Coeline ou l'enfant du mystère». Sin embargo es indiscutible la influencia que sobre los escritores franceses del XIX ejerció este género menor, que no solo leyó con fruición un gran novelista como Mérimée, sino que sirvió de fuente de inspiración al «monstruo» de las letras francesas y gran héroe nacional, el gran Hugo, en alguno de sus primeros ensayos novelísticos: «Bug-Jargal» y «Hans d'Islande».

  10. Jules Horowitz Reactor Project- Fuel irradiation device, innovative instrumentation proposal for experimental phenomena real time measurement

    Energy Technology Data Exchange (ETDEWEB)

    Gaillot, Stephane; Cheymol, Guy [CEA, Paris (France)

    2013-07-01

    The fuel irradiation devices used for the tests or rods allow reproducing at small scales the conditions of the studied nuclear reactors (as LWR type). During the irradiation phase, the tested fuel rod can be stressed due to thermal, mechanical, nuclear effects which can modify its geometry (dilatation, swelling effects). After the test, the return to normal conditions can have as consequence the disappearance of the phenomenon or give access to partial information (final deformation). Generally, to follow the phenomena related to the irradiation phase, the experimental rod contained in the test device is instrumented with thermocouples and LVDT. As complement of this instrumentation, new sensors using innovating technologies are studied (deformation sensor integrating optical fibres). Through the example of a fuel irradiation device foreseen for the JHR, this paper aims to describe the present development of an innovating instrumentation with the objective to measure, in real time and under flux, the fuel rod deformation phenomena during a ramp test.

  11. About Jules et Jim: Some Figures of Matriarchy from Bachofen to Truffaut via Benjamin, Roché and Hessel

    Directory of Open Access Journals (Sweden)

    Michael Hollington

    1997-05-01

    Full Text Available Cet article essaie de relever quelques aspects d'un mouvement de pensée « matriarcale » du XXe siècle, parfois plutôt souterrain, et de montrer dans quelle mesure cette pensée fait partie du contexte du grand film des années soixante de François Truffaut. Il s'agit des hypothèses de Johann Jakob Bachofen (1815-1887, juriste et archéologue suisse, qui proposait la théorie d'un matriarcat primitif à l'origine de la société humaine. Dans un premier temps, en Méditerranée par exemple, existait selon lui un système communiste où l'idée de propriété privée était absente, fondé sur l'« hétaïrisme », où les rapports sexuels, organisés selon les vœux des femmes, étaient complètement libres.The purpose of this paper is, first, to provide a brief sketch map of a comparative nature of some linked, formative appropriations in Germany and elsewhere in the early part of this century of the Swiss jurist and archaeologist Johann Jakob Bachofen (1815-1887, famous for his influential but controversial theory of the precedence of primitive matriarchy over patriarchy in the Mediterranean and elsewhere.Este artίculo trata de señalar algunos aspectos de una corriente de pensamiento "matriarcal" del siglo veinte, a veces más bien subterránea, y muestra en qué medida dicho pensamiento forma parte del contexto de la famosa película de los años sesenta de François Truffaut. Se trata de las hipótesis de Johann Jakob Bachofen (1815-1887, jurista y arqueólogo suizo, quien propuso la teoría de un matriarcado primitivo en el origen de la sociedad humana. En un primer momento, en la región mediterránea, por ejemplo, dice que existía un sistema comunista carente de la idea de propiedad privada, y basado en el "hetaerismo", en el que las relaciones sexuales, organizadas según el voto de las mujeres, eran completamente libres.

  12. 博尔德(Border,Jules Jean Baptiste Vincent.1870-1961)比利时微生物学家(Microbiologist,Belgium)

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    博尔德于1892年在布鲁塞尔大学获得医学博士学位,随后又到巴黎巴斯德P6研究所,在梅契尼科夫指导下工作。1901年,他在布鲁塞尔也创建了一个巴斯德研究所并亲任所长。1898年,博尔德发现,如果把血清加热到55℃,尽管血清中的抗体不致受到破坏,但却丧失了摧毁细菌的能力。由此可以推断,血清中一定含有某种或某组非常脆弱的成分作为抗体的补体,使之能够与细菌发生作用。

  13. Falquet Jules, Hirata Helena, Kergoat Danièle, Labari Brahim, Le Feuvre Nicky, Sow Fatou(Dir., Le sexe de la mondialisation

    Directory of Open Access Journals (Sweden)

    Olivier Giraud

    2011-09-01

    Full Text Available L’ouvrage Le sexe de la mondialisation – Genre, classe, race et nouvelle division du travail mérite une grande attention de la communauté académique et au-delà, pour au moins quatre raisons. En premier lieu, cet ouvrage traite d’une question essentielle pour la compréhension du monde contemporain, celle de la dimension genrée de la mondialisation. En deuxième lieu, il réunit une équipe d’auteures et auteurs francophones et autres (plus de la moitié des textes sont traduits de l’anglais de pr...

  14. Development and experimental qualification of a calculation scheme for the evaluation of gamma heating in experimental reactors. Application to MARIA and Jules Horowitz (JHR) MTR Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Tarchalski, M.; Pytel, K.; Wroblewska, M.; Marcinkowska, Z.; Boettcher, A.; Prokopowicz, R. [NCBJ Institute, MARIA Reactor, ul.Andrzeja Soltana 7, 05-400 Swierk (Poland); Sireta, P.; Gonnier, C.; Bignan, G. [CEA, DEN, Reactor Studies Department, Cadarache, F-13108 St-Paul-Lez-Durance (France); Lyoussi, A.; Fourmentel, D.; Barbot, L.; Villard, J.F.; Destouches, C. [CEA, DEN, DER, Instrumentation Sensors and Dosimetry Laboratory, Cadarache, F-13108 St-Paul-Lez-Durance (France); Reynard-Carette, C.; Brun, J. [Aix Marseille Universite, CNRS, Universite de Toulon, IM2NP UMR 7334, 13397, Marseille (France); Jagielski, J. [NCBJ Institute, MARIA Reactor, ul.Andrzeja Soltana 7, 05-400 Swierk (Poland); Institute of Electronic Materials Technolgy, Wolczynska 133, 01-919 Warszawa (Poland); Luks, A. [Institute of Heat Engineering, Nowowiejska 21/25, 00-665 Warsaw (Poland)

    2015-07-01

    Precise computational determination of nuclear heating which consists predominantly of gamma heating (more than 80 %) is one of the challenges in material testing reactor exploitation. Due to sophisticated construction and conditions of experimental programs planned in JHR it became essential to use most accurate and precise gamma heating model. Before the JHR starts to operate, gamma heating evaluation methods need to be developed and qualified in other experimental reactor facilities. This is done inter alia using OSIRIS, MINERVE or EOLE research reactors in France. Furthermore, MARIA - Polish material testing reactor - has been chosen to contribute to the qualification of gamma heating calculation schemes/tools. This reactor has some characteristics close to those of JHR (beryllium usage, fuel element geometry). To evaluate gamma heating in JHR and MARIA reactors, both simulation tools and experimental program have been developed and performed. For gamma heating simulation, new calculation scheme and gamma heating model of MARIA have been carried out using TRIPOLI4 and APOLLO2 codes. Calculation outcome has been verified by comparison to experimental measurements in MARIA reactor. To have more precise calculation results, model of MARIA in TRIPOLI4 has been made using the whole geometry of the core. This has been done for the first time in the history of MARIA reactor and was complex due to cut cone shape of all its elements. Material composition of burnt fuel elements has been implemented from APOLLO2 calculations. An experiment for nuclear heating measurements and calculation verification has been done in September 2014. This involved neutron, photon and nuclear heating measurements at selected locations in MARIA reactor using in particular Rh SPND, Ag SPND, Ionization Chamber (all three from CEA), KAROLINA calorimeter (NCBJ) and Gamma Thermometer (CEA/SCK CEN). Measurements were done in forty points using four channels. Maximal nuclear heating evaluated from measurements is of the order of 2.5 W/g at half of the possible MARIA power - 15 MW. The approach and the detailed program for experimental verification of calculations will be presented. The following points will be discussed: - Development of a gamma heating model of MARIA reactor with TRIPOLI 4 (coupled neutron-photon mode) and APOLLO2 model taking into account the key parameters like: configuration of the core, experimental loading, control rod location, reactor power, fuel depletion); - Design of specific measurement tools for MARIA experiments including for instance a new single-cell calorimeter called KAROLINA calorimeter; - MARIA experimental program description and a preliminary analysis of results; - Comparison of calculations for JHR and MARIA cores with experimental verification analysis, calculation behavior and n-γ 'environments'. (authors)

  15. Breast cancer and per-operation electron radiotherapy: a review of the first 100 patients treated at the Jules-Bordet Institute; Cancer du sein et radiotherapie peroperatoire par electrons: revue des 100 premieres patientes traitees a l'institut Jules-Bordet

    Energy Technology Data Exchange (ETDEWEB)

    Philippson, C.; Simon, S.; Vandekerkhove, C.; Veys, I.; Noterman, D.; Hertens, D.; Neubourg, F. De; Larsimont, D.; Van Houtte, P.; Nogaret, J.M. [Institutjules-Bordet, Bruxelles (Belgium)

    2011-10-15

    The authors briefly discuss the results obtained on a cohort of women treated by per-operation radiotherapy for breast cancer. This technique enables a dose equivalent to that of a conventional fractionated external radiotherapy to be delivered in a single session in the tumour bed. Moreover, a weaker dose can be delivered as a boost before a conventional irradiation. Immediate morbidity is steady. Some rare complications have been noticed. Short communication

  16. A Transportation Model for a Space Colonization and Manufacturing System: A Q-GERT Simulation.

    Science.gov (United States)

    1982-12-01

    their audiences glimpses of what could be. Jules Verne , considered by many people as the father of science fiction, fortold many of our modern...Publishing Company, 1966. 2. Verne , Jules . Emm iha Eari. Jk ±ha t ! . Paris: 1873. 3. Verne , Jules . f nan a Comet. Paris: 1878. 4. Salkeld, Robert

  17. Child Development Theory as a Mediator of Novice Teachers' Ethnotheories to Increase Learning and Justice in the Classroom

    Science.gov (United States)

    Cardwell, Nancy Michele

    2014-01-01

    Many urban public schools use teaching methods that isolate and silence children to compel compliance (Schwebel, 2004; Saltman & Gabbard, 2003; Baumrind, 1991). In these contexts, black and brown children are disciplined more often and harshly than white, sent through the court system 70% of the time (Alexander, 2012). Novice teachers,…

  18. Child Development Theory as a Mediator of Novice Teachers' Ethnotheories to Increase Learning and Justice in the Classroom

    Science.gov (United States)

    Cardwell, Nancy Michele

    2014-01-01

    Many urban public schools use teaching methods that isolate and silence children to compel compliance (Schwebel, 2004; Saltman & Gabbard, 2003; Baumrind, 1991). In these contexts, black and brown children are disciplined more often and harshly than white, sent through the court system 70% of the time (Alexander, 2012). Novice teachers,…

  19. Material Specters: International Conflicts, Disaster Management, and Educational Projects

    Science.gov (United States)

    Papastephanou, Marianna

    2011-01-01

    In this essay, Marianna Papastephanou discusses three books--Michalinos Zembylas's "The Politics of Trauma in Education"; Sigal Ben-Porath's "Citizenship Under Fire: Democratic Education in Times of Conflict"; and Kenneth Saltman's "Capitalizing on Disaster: Taking and Breaking Public Schools"--from the perspective of the material causality of…

  20. Material Specters: International Conflicts, Disaster Management, and Educational Projects

    Science.gov (United States)

    Papastephanou, Marianna

    2011-01-01

    In this essay, Marianna Papastephanou discusses three books--Michalinos Zembylas's "The Politics of Trauma in Education"; Sigal Ben-Porath's "Citizenship Under Fire: Democratic Education in Times of Conflict"; and Kenneth Saltman's "Capitalizing on Disaster: Taking and Breaking Public Schools"--from the perspective of the material causality of…

  1. 从艾儒略到朱自清:游记与"浪漫法兰西"形象的生成%From Jules Aleni to Zhu Ziqing: On Travel Netes and Creation of the Image of Romantic France in China

    Institute of Scientific and Technical Information of China (English)

    孟华

    2006-01-01

    什么词最能概括现代中国人心目中的法国形象?大多数人选择"浪漫"一词.但若再深问一句:法国何以是浪漫的?答案莫衷一是.本文认为,"浪漫法兰西"形象的起源始自法国神甫艾儒略的游记在中国的译介.张德彝和王韬追随艾儒略,现当代作家又追随张德彝和王韬,现代中国人心目中的"浪漫法兰西"形象就是在这种"同质"与"异质"的"互文"中构成的.

  2. 从艾儒略到朱自清:游记与"浪漫法兰西"形象的生成%From Jules Aleni to Zhu Ziqing:Travel accounts and the construction of "Romantic France"

    Institute of Scientific and Technical Information of China (English)

    孟华

    2008-01-01

    Many Chinese believe that France is a"romantic"nation though they may offer different answers to the question"Why".A recent source study shows that this image comes from the travel note written by a French priest Julie Aleni when he took a mission in China,from Wonders in the Voyage and Traveling around Europe and America by Zhang Deyi,a Chinese diplomat in France at that time and from Travel Notes by Wang Tao.Therefore,many Chinese modem writers borrowed this image to their works.Hence it has been created as a set image in the intertextual context of cultural homogeneity and heterogeneity.Therefore,this paper is intended to trace the signs of these cultural interactions so as to see how"Romantic France"has come to be a set image in Chinese culture.%什么词最能概括现代中国人心目中的法国形象?大多数人选择"浪漫"一词.但若再深问一句:法国何以是浪漫的?答案莫衷一是."浪漫法兰西"形象的起源始自法国神甫艾儒略的游记在中国的译介.张德彝和王韬追随艾儒略,现当代作家又追随张德彝和王韬,现代中国人心目中的"浪漫法兰西"形象就是在这种"同质"与"异质"的"互文"中构成的.

  3. The Missions of the United States Air Force in the 22nd Century

    Science.gov (United States)

    2009-04-01

    facility, rapidity and certainty as we now make the ocean voyage from Liverpool to New York. — Jules Verne , From the Earth to the Moon, 1865...space travel even though Jules Verne quite remarkably predicted the event 35 years earlier in From the Earth to the Moon. 3 The ―deadly...in the Next Hundred Years,‖ Ladies Home Journal, December 1900, 8. 3 Jules Verne describes manned spaceflight using a bullet-shaped capsule fired

  4. JPRS Report. Science & Technology: Europe.

    Science.gov (United States)

    1991-03-29

    represent a power of 3,200 kilowatt, the " Jules Verne " climatic wind tunnel can reproduce all the components of a given climate to evaluate a... Jules Verne wind tunnel meets the requirements of research and industry and numerous public and private contracts have already been entered into...CSTB. [Box] Performance of the Jules Verne Wind Tunnel (Stages 1 and 2) Top wind speed: 310 km/h (30 m2 section) Temperature range: from -25" C

  5. French school and World War First: neurological consequences of a frightening time.

    Science.gov (United States)

    Gomes, Marleide da Mota

    2015-05-01

    Some aspects of a dark period in the history of the modern neurology, that of the World War I (WWI), are here remembered, mainly by the neurological French School participation . Some personalities and their works related to the WWI are presented such as Joseph Babinski, Jules Froment, Clovis Vincent, Jules Joseph Dejerine, Augusta Déjérine-Klumpke, Jules Tinel, Pierre Marie, Achille Alexandre Souques, Charles Foix, and Georges Guillain.

  6. French school and World War First: neurological consequences of a frightening time

    Directory of Open Access Journals (Sweden)

    Marleide da Mota Gomes

    2015-05-01

    Full Text Available Some aspects of a dark period in the history of the modern neurology, that of the World War I (WWI, are here remembered, mainly by the neurological French School participation . Some personalities and their works related to the WWI are presented such as Joseph Babinski, Jules Froment, Clovis Vincent, Jules Joseph Dejerine, Augusta Déjérine-Klumpke, Jules Tinel, Pierre Marie, Achille Alexandre Souques, Charles Foix, and Georges Guillain.

  7. Governance in Health - The Need for Exchange and Evidence Comment on "Governance, Government, and the Search for New Provider Models".

    Science.gov (United States)

    Chanturidze, Tata; Obermann, Konrad

    2016-05-17

    Governance in health is cited as one of the key factors in balancing the concerns of the government and public sector with the interests of civil society/private players, but often remains poorly described and operationalized. Richard Saltman and Antonio Duran look at two aspects in the search for new provider models in a context of health markets signalling liberalisation: (i) the role of the government to balance public and private interests and responsibilities in delivering care through modernised governance arrangements, and (ii) the finding that operational complexities may hinder well-designed provider governance models, unless governance reflects country-specific realities. This commentary builds on the discussion by Saltman and Duran, and argues that the concept of governance needs to be clearly defined and operationalized in order to be helpful for policy debate as well as for the development of an applicable framework for performance improvement. It provides a working definition of governance and includes a reflection on the prevailing cultural norms in an organization or society upon which any governance needs to be build. It proposes to explore whether the "evidence-based governance" concept can be introduced to generate knowledge about innovative and effective governance models, and concludes that studies similar to the one by Saltman and Duran can inform this debate.

  8. The Jobs behind the Science

    CERN Multimedia

    Jacques Fichet; Jules Ordan; Anna Cook; Jacques Fichet

    2015-01-01

    Recruitments service promotes this clip "The Jobs behind the Science" Réalisé par Jules Ordan Produit par Jacques Fichet Voix off Anna Cook Musique : Unphased. Les musiciens: - Carlos Rosales - Tim McGarry - Ary Porat - Elio Jaillet - Jules Ordan - Didier Fellay

  9. Guidance and Navigation Software Architecture Design for the Autonomous Multi-Agent Physically Interacting Spacecraft (AMPHIS) Test Bed

    Science.gov (United States)

    2006-12-01

    class, the Jules Verne successfully completed the autonomous rendezvous and docking system in Europe’s largest ship hull test facility in September...replicate the 2007 Jules Verne mission. http://www.esa.int/SPECIALS/ATV/SEMWCEKKKSE_0.html. 23. Banke, K., Air Force XSS-10 Micro-Satellite Mission a

  10. America’s Energy Security Policy: Goals for 2025

    Science.gov (United States)

    2007-02-01

    vehicles. The promise of hydrogen technology is too great to ignore. In his 1874 novel, The Mysterious Island, Jules Verne described a world in...The Reference Shelf, Energy Policy, volume 74, Number 2 (H. W. Wilson, February 2002), 3-4. 75 Jules Verne , The Mysterious Island, 1874, original

  11. USSR Report, Space, No. 19.

    Science.gov (United States)

    1983-01-31

    for correcting the trajectory and deceleration upon land- ing ( Jules Verne "De la Terre ä la Lune", 1870), on an artificial earth satel- lite used...is set forth by Jules Verne in "Five Hundred Million Begums" (1879). Finally, the novelist’s fantasy uses a jet engine operating on nuclear energy

  12. The Role of History in Teaching Science--A Case Study: The Popularization of Science in Nineteenth-Century France.

    Science.gov (United States)

    Hendrick, Robert M.

    1992-01-01

    Examines one of the key methods used to stimulate bourgeois interest in science in France during the Second Empire and early Third Republic; the campaign to create a popularized science. Concentrates on the "science writings" of Jules Michelet and Jules Verne, both of whom were immensely successful in creating a favorable climate of…

  13. Safe Ride Standards for Casualty Evacuation Using Unmanned Aerial Vehicles (Normes de transport sans danger pour l’evacuation des blesses par vehicules aeriens sans pilote)

    Science.gov (United States)

    2012-12-01

    type of limited in-flight care. Unfortunately, this forward-looking concept, which gained him the sobriquet of “the Jules Verne of aviation medicine... Jules Verne Van Den Gezondheids-Luchtdienst”. ANNEX B – HISTORY AND DEVELOPMENT OF AERIAL EVACUATION, WITH SPECIFIC REFERENCE TO UAV POTENTIAL USE

  14. Developing and Populating the Global Information Grid for Joint and Coalition Operations: Challenges and Opportunities

    Science.gov (United States)

    2004-06-01

    SPRINGFIELD (SSN) NON-OEF TASKING FS AIGLE (MHC) FS DAGUE (LCT) FS D’ENTRECASTEAUX (AGS) FS FLOREAL (FFG) FS ISARD (AG) FS JULES VERNE (AD) FS LA...ISARD (AG) FS JULES VERNE (AD) FS LA LAVALLEE (FFG) FS LOIRE (AG) FS SIROCO (LSD) FS VAR (AOR) FS VERSEAU (MHC) HMS SPLENDID (SSN) INPORT MUSCAT RBNS

  15. Improving the Fit of a Land-Surface Model to Data Using its Adjoint

    Science.gov (United States)

    Raoult, Nina; Jupp, Tim; Cox, Peter; Luke, Catherine

    2016-04-01

    Land-surface models (LSMs) are crucial components of the Earth System Models (ESMs) which are used to make coupled climate-carbon cycle projections for the 21st century. The Joint UK Land Environment Simulator (JULES) is the land-surface model used in the climate and weather forecast models of the UK Met Office. In this study, JULES is automatically differentiated using commercial software from FastOpt, resulting in an analytical gradient, or adjoint, of the model. Using this adjoint, the adJULES parameter estimation system has been developed, to search for locally optimum parameter sets by calibrating against observations. We present an introduction to the adJULES system and demonstrate its ability to improve the model-data fit using eddy covariance measurements of gross primary production (GPP) and latent heat (LE) fluxes. adJULES also has the ability to calibrate over multiple sites simultaneously. This feature is used to define new optimised parameter values for the 5 Plant Functional Types (PFTS) in JULES. The optimised PFT-specific parameters improve the performance of JULES over 90% of the FLUXNET sites used in the study. These reductions in error are shown and compared to reductions found due to site-specific optimisations. Finally, we show that calculation of the 2nd derivative of JULES allows us to produce posterior probability density functions of the parameters and how knowledge of parameter values is constrained by observations.

  16. Scientific Satellites

    Science.gov (United States)

    1967-01-01

    followed Hale’s into orbit. In 1879, Jules Verne wrote about launching small satellites with a gun possessing a muzzle velocity of 10 000 m/sec (ref. 3...was activated in 1950.11 It was located only a few tens of miles from the spot where Jules Verne had his Baltimore Gun Club fire a manned projectile to...principle, satellites can be launched by a single impulse applied at the Earth’s surface-say, with a large cannon, & la Jules Verne (sec. 8-3). In

  17. Risks and Opportunities of Reforms Putting Primary Care in the Driver’s Seat; Comment on “Governance, Government, and the Search for New Provider Models”

    Directory of Open Access Journals (Sweden)

    Monica Andersson Bäck

    2016-08-01

    Full Text Available Recognizing the advantages of primary care as a means of improving the entire health system, this text comments on reforms of publicly funded primary health centers, and the rapid development of private forprofit providers in Sweden. Many goals and expectations are connected to such reforms, which equally require critical analyses of scarce resources, professional trust/motivation and business logic in the wake of freedom and control of ownership and management. In line with Saltman and Duran, this article calls for research and a methodologically developed approach to capture everyday practice in-depth and how regulation, market incentives and patient demands are met by professionals and primary care leaders.

  18. Punane Veski ja plakatikunsti algus / Riina Robinson

    Index Scriptorium Estoniae

    Robinson, Riina

    2007-01-01

    Prantsuse plakatikunsti loojast Jules Cheret'st, ühest silmapaistvamast plakati- ja maalikunstnikust Henri Toulouse-Lautrecist, tema plakatite kangelannadest, kankaani tantsinud Louise Weberist ja Jane Avrilist ning Moulin Rouge'ist

  19. Air Force Contract Negotiations: Importance, Roles, and Major Problems in the United States and Four NATO Countries

    Science.gov (United States)

    1982-06-01

    Aldine Publishing Co., 1964. Backman, Jules , ed. Social Responsibility and Accountability. New York: New York University Press, 1975. Bartos...Conflict. New York: Academic Press, 1970. Terpstra, Vern . International Marketing. Dryden Press, 1972. .. The Cultural Environment of International

  20. Lennujaamast ja parunist puu otsas : [lugemiselamustest] / Ülar Ploom

    Index Scriptorium Estoniae

    Ploom, Ülar

    2007-01-01

    Maailmaklassikast: Mark Twaini "Huckelberry Finni seiklused", Jules Verne'i "Saladuslik saar", Gabriel García Márquezi "Sada aastat üksildust", Aleksandr Erteli "Gardeninid", Italo Calvino "Parun puu otsas"

  1. "Gypsy" ehk killuke Ameerikat meie jaoks / Martin Gorris

    Index Scriptorium Estoniae

    Gorris, Martin

    2001-01-01

    2. dets. esietendus Vanemuises Ameerika vodevillistaari ja striptiisikuninganna Rose Louise Hovicki memuaaridel põhinev Jule Styne'i muusikal "Gypsy", lavastaja Mare Tommingas, osades Silvi Vrait ja Helena Merzin

  2. Innate immunity's path to the Nobel Prize 2011 and beyond

    National Research Council Canada - National Science Library

    Wagner, Hermann

    2012-01-01

    The 2011 Nobel Prize in Physiology/Medicine to Ralph Steinmann, Jules Hoffmann, and Bruce Beutler recognized a paradigm shift in our understanding of innate immunity, and its impact on adaptive immunity...

  3. Lennujaamast ja parunist puu otsas : [lugemiselamustest] / Ülar Ploom

    Index Scriptorium Estoniae

    Ploom, Ülar

    2007-01-01

    Maailmaklassikast: Mark Twaini "Huckelberry Finni seiklused", Jules Verne'i "Saladuslik saar", Gabriel García Márquezi "Sada aastat üksildust", Aleksandr Erteli "Gardeninid", Italo Calvino "Parun puu otsas"

  4. Evaluating the change of directional patterns for fingerprints with missing singular points under rotation

    CSIR Research Space (South Africa)

    Dorasamy, Kribashnee

    2016-12-01

    Full Text Available ) Advances in Visual Computing. ISVC 2016. Lecture Notes in Computer Science, vol 10073. Evaluating the Change of Directional Patterns for Fingerprints with Missing Singular Points Under Rotation Kribashnee Dorasamy Leandra Webb-Ray Jules...

  5. Massenet "Thaisi" näeb otseülekandes kinolinal / Toomas Kuter

    Index Scriptorium Estoniae

    Kuter, Toomas, 1965-

    2008-01-01

    Forum Cinemas toob oktoobrist maini Tallinnas Coca-Cola Plazas ja Tartus Ekraanis publikuni New Yorgi Metropolitan Opera etenduste HD-otseülekanded, 20. dets. kantakse üle Jules Massenet' ooper "Thais", peaosas Renee Fleming

  6. "Thais" muusika on fenomenaalne / Veronika Džiojeva ; intervjueerinud Silja Joon

    Index Scriptorium Estoniae

    Džiojeva, Veronika

    2009-01-01

    Küsimustele vastab 22. mail Pärnu Endla teatris esietenduva Jules Massenet' ooperi "Thais" nimiosatäitja, 2007. aastal toimunud Klaudia Taevi nim. rahvusvahelise ooperilauljate konkursi laureaat Veronika Džiojeva

  7. Tribute to a Leading Personality of World Horticultural Science

    OpenAIRE

    2010-01-01

    Following the proposal of Academic Council of Horticulture Faculty, the Senate of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca accepted nominee Professor Jules Janick for Doctor Honoris Causa award. The title was awarded in festive ceremony on September 30, 2010. Jules Janick, Professor at Purdue University has a long and distinguished career devoted to horticulture in all its facets. In horticultural research, he has made important advances including the gen...

  8. On stage at the Globe

    CERN Document Server

    2005-01-01

    The Globe's first season this year is to be rounded off with two shows that are in perfect keeping with the centenary of the death of Jules Verne and Albert Einstein's theory of relativity. 'Signé Jules Verne' (Signed Jules Verne) The Miméscope company, which has already thrilled audiences at CERN with shows such as the 'Oracle of Delphi' and, more recently, 'Point de Suspension', returns with an interactive show entitled 'Signé Jules Verne'. Imagine a slightly crazy machine, which rolls along on wheels, floats, flies or moves in any other way you like, as long as it works on scientific principles. This is the task that Jules Verne sets his audience. Experiments, models, drawings, blueprints, he's interested in them all. In its typical style, Miméscope has created a world of enchantment that combines theatre, choreography, music and lighting effects in a show that evolves as a function of its audience. Performances at 3.00 p.m. on 4, 7, 10 and 11 December An interactive show for the general public...

  9. Governance Must Dive Into Organizations to Make a Real Difference; Comment on “Governance, Government, and the Search for New Provider Models”

    Directory of Open Access Journals (Sweden)

    Jean-Louis Denis

    2017-01-01

    Full Text Available In their 2016 article, Saltman and Duran provide a thoughtful examination of the governance challenges involved in different care delivery models adopted in primary care and hospitals in two European countries. This commentary examines the limited potential of structural changes to achieve real reform and considers that, unless governance arrangements actually succeed in penetrating organizations, they are unlikely to improve care. It proposes three sets of levers influenced by governance that have potential to influence what happens at the point of care: harnessing the autonomy and expertise of professionals at a collective level to work towards better safety and quality; creating enabling contexts for cross-fertilization of clinical and organizational expertise, notably through teamwork; and patient and public engagement to achieve greater agreement on improvement priorities and overcome provider/manager tensions. Good governance provides guidance at a distance but also goes deep enough to influence clinical habits.

  10. Governance Must Dive Into Organizations to Make a Real Difference

    Science.gov (United States)

    Denis, Jean-Louis; Usher, Susan

    2017-01-01

    In their 2016 article, Saltman and Duran provide a thoughtful examination of the governance challenges involved in different care delivery models adopted in primary care and hospitals in two European countries. This commentary examines the limited potential of structural changes to achieve real reform and considers that, unless governance arrangements actually succeed in penetrating organizations, they are unlikely to improve care. It proposes three sets of levers influenced by governance that have potential to influence what happens at the point of care: harnessing the autonomy and expertise of professionals at a collective level to work towards better safety and quality; creating enabling contexts for cross-fertilization of clinical and organizational expertise, notably through teamwork; and patient and public engagement to achieve greater agreement on improvement priorities and overcome provider/manager tensions. Good governance provides guidance at a distance but also goes deep enough to influence clinical habits. PMID:28005542

  11. Governance: Blending Bureaucratic Rules with Day to Day Operational Realities Comment on "Governance, Government, and the Search for New Provider Models".

    Science.gov (United States)

    Chinitz, David P

    2016-05-31

    Richard Saltman and Antonio Duran take up the challenging issue of governance in their article "Governance, Government and the Search for New Provider Models," and use two case studies of health policy changes in Sweden and Spain to shed light on the subject. In this commentary, I seek to link their conceptualization of governance, especially its interrelated roles at the macro, meso, and micro levels of health systems, with the case studies on which they report. While the case studies focus on the shifts in governance between the macro and meso levels and their impacts on achievement of desired policy outcomes, they also highlight the need to better integrate the dynamics of day to day operations within micro organizations into the overall governance picture.

  12. Governance Must Dive Into Organizations to Make a Real Difference Comment on "Governance, Government, and the Search for New Provider Models".

    Science.gov (United States)

    Denis, Jean-Louis; Usher, Susan

    2016-07-03

    In their 2016 article, Saltman and Duran provide a thoughtful examination of the governance challenges involved in different care delivery models adopted in primary care and hospitals in two European countries. This commentary examines the limited potential of structural changes to achieve real reform and considers that, unless governance arrangements actually succeed in penetrating organizations, they are unlikely to improve care. It proposes three sets of levers influenced by governance that have potential to influence what happens at the point of care: harnessing the autonomy and expertise of professionals at a collective level to work towards better safety and quality; creating enabling contexts for cross-fertilization of clinical and organizational expertise, notably through teamwork; and patient and public engagement to achieve greater agreement on improvement priorities and overcome provider/manager tensions. Good governance provides guidance at a distance but also goes deep enough to influence clinical habits.

  13. Military Use of the International Space Station

    Science.gov (United States)

    1988-11-01

    projectile ( Jules Verne , 1865, and others); or, when all else failed, anti-gravity machines, paint, or water. W. von Braun and F. Ordway, History of Rocketry...centuries. From Lucian’s second century account of a sailing ship being swept by winds to the moon I to Jules Verne’s De la Terre a La Lune (From the Earth...Travel, at 9 (rev. ed. 1969). 2J. Verne , From the Earth to the Moon (1970 ed.). 3Hall, The Brick Moon, Atl. Monthly, Oct. 1869, at 451; Nov. 1869, at

  14. Modern Technology Transforming Virtuosos Into Conductors

    Science.gov (United States)

    2010-04-01

    is a killer in the battlespace Inhibits decisiveness Overwhelms the receiver Jeopardizes the mission Don’t discount fantasy/Science Fiction Jules   Vern ...Inhibits decisiveness Overwhelms the receiver Jeopardizes the mission Don’t discount fantasy/Science Fiction Jules   Vern   ‐ Nuke Subs Robert Heinlein – Starship Troopers      George Lucas ‐ Starwars 5/4/2010 15SSTC 2010

  15. Hysteria in fin de siècle French novels.

    Science.gov (United States)

    Walusinski, Olivier

    2013-01-01

    During the second half of the 19th century, sociopolitical conditions and society's interest in psychological questions transformed the millennial concept of hysteria into a sociocultural representation of the female condition and sexuality. Influenced by the public demonstrations of Jean-Martin Charcot at La Salpêtrière, many writers attempted to magnify this neurologist's work in their novels. In this chapter, we will analyze several representative passages written by Jules Clarétie, Camille Lemonnier, Jules Lermina, Octave Mirbeau, Joris-Karl Huysmans, and Gustave Flaubert, bearing in mind the scientific, progressive, and anticlerical ideas of the time.

  16. Alle ønsker sig en Lego-aktie til jul

    DEFF Research Database (Denmark)

    Iversen, Martin Jes

    2014-01-01

    Både små og store investorer får julelys i øjnene ved tanken om at eje et stykke af Lego. På sigt kunne en børsnotering gøre Danmark til et rigere land.......Både små og store investorer får julelys i øjnene ved tanken om at eje et stykke af Lego. På sigt kunne en børsnotering gøre Danmark til et rigere land....

  17. Kirjandus ja vabamüürlus / Paavo Matsin

    Index Scriptorium Estoniae

    Matsin, Paavo, 1970-

    2009-01-01

    Loetletakse vabamüürlastest kirjanikke (pikemalt Jules Verne'ist, Gustav Meyrinkist, Rudyard Kiplingist ja Mait Metsanurgast) ning vabamüürlikke tegelasi või motiive kasutanud kirjanikke (Lev Tolstoi, Fjodor Dostojevski, Mihhail Bulgakov, Edgar Allan Poe)

  18. Computer-Assisted Eye Examination: Background and Prospects.

    Science.gov (United States)

    1982-05-01

    bookkeeping work. The most successful prophet of lcchnology, Jules Verne , predicted much of 20th century technical progress. Few scientists took him...de los antojos Seville: Diego Perez, De Valdds. B. D. (1623b) Usit de los antajos. Ed M Mhrque. Madrid: Julio Casano. Westheimer, G. (19571

  19. An Analysis of Tactical Military Airlift

    Science.gov (United States)

    1997-09-01

    Major William Scott of AFIT; MSGT (Ret.) Gaye Summitt and MSGT (Ret.) Vern Moore, who took a fledgling Lieutenant under their wings and molded him into...Decision: The Siege of Khe Sanh. New York: Houghton Mifflin Company. Roy, Jules . 1965. The Battle of Dienbienphu. New York: Harper & Row. Shore, Moyers

  20. What Is Steampunk, and Do I Want It in My Library?

    Science.gov (United States)

    Rozmus, Emily

    2011-01-01

    What is steampunk? Most call it Victorian science fiction. Steampunk can claim such authors as H.G. Wells and Jules Verne as its earliest writers. These two Victorian/Edwardian era writers created steampunk settings in books such as "The Time Machine" and "Journey to the Center of the Earth". In the 1990s, writers such as William Gibson, Bruce…

  1. Air Force Health Study. An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. First Followup Examination Results. Volume 1

    Science.gov (United States)

    1987-10-01

    follovup examination, 4 vere Ranch Hands and 6 vere Comparisons. This difference vas not statistically s$gnific nt and the data vern insufficlant for...higher proportion of individuals with white blood cell eounts exceeding 10,000/mm was in the exposed group. hase~ jule Sume.ary Lesults A nunber of

  2. Leadership in the Era of the Human Singularity: New Demands, New Skills, New Response

    Science.gov (United States)

    2008-10-01

    Leadership in the era of the human singuLarity84 Such claims are not based on the Late Victorian and Edwardian futurism of H.G. Welles, Edward Bellamy, Jules ... Verne , and the great expositions of the 1890s and early 1900s. In the first place, we have today many, many times more experience observing the

  3. Reach for the Stars: Visions for Literacy Coaching Programs

    Science.gov (United States)

    DeFord, Diane

    2012-01-01

    This brief by the Literacy Coaching Clearinghouse is about reaching for the stars--stories of vision and commitment from educators in small and large schools. Everyone knows of people who are held up as "visionaries" throughout history: Leonardo Da Vinci, Mahatma Gandhi, Jules Verne, Thomas Edison, Susan Anthony, or John Dewey, to name a few. The…

  4. Chemistry and Defects in Semiconductor Heterostructures. Materials Research Society Symposium Proceedings. Volume 148

    Science.gov (United States)

    1990-05-01

    energ7y for an overomowtbh (141. This work was sapported by’he𔃿.lpartmest ofPCro-t-CC-’F D53) r. Jules Soatbort, contract monitor, for which muon...found, indicating a single crystalline material. The patterns, however, are verN sensitive to small non-uniform lattice strains which can be detected to

  5. Rapid Oceanographic Data Gathering: Some Problems in Using Remote Sensing to Determine the Horizontal and Vertical Thermal Distributions in the Northeast Pacific Ocean.

    Science.gov (United States)

    1981-09-01

    OCEANOGRAPHIC RESEARCH In 1870 and 1879 respectively, the authors Edward Everett Hale and Jules Verne wrote about placing an artificial satellite in orbit...Hale using a huge waterpowered flywheel and Verne a gun of sufficient muzzle velocity (Corliss, 1967). Hale envisioned the satellite as an aid to

  6. Detjam kapitana Granta privezli iz Ameriki bizonov i straussov / Margarita Golovanova

    Index Scriptorium Estoniae

    Golovanova, Margarita

    2006-01-01

    Kuidas "Mosfilmis" filmiti Jules Verne'i järgi mängufilmi "Kapten Granti lapsed" : režissöör Vladimir Vainshtok : helilooja Isaak Dunajevski : näitlejad Nikolai Tsherkassov, Jakov Segel : NSV Liit 1936

  7. Combining Performance and Flexibility for RMS with a Hybrid Architecture

    NARCIS (Netherlands)

    Arjan van Zanten; Dick van der Steen; Dennis Koole; Ing. Erik Puik; Patrick Wit; Pascal Muller; Leo van Moergestel; Arjan Groenewegen; John-Jules Meyer; Daniël Telgen

    2013-01-01

    Author supplied Combining Performance and Flexibility for RMS with a Hybrid Architecture Dani¨el Telgen 12? , Leo van Moergestel 1 , Erik Puik 1 , Pascal Muller 1 , Arjan Groenewegen 1 , Dick van der Steen 1 , Dennis Koole 1 , Patrick de Wit 1 , Arjen van Zanten 1 , and John-Jules

  8. The JHR reactor: a multipurpose asset for materials; Le reacteur RHJ: polyvalence au service des materiaux

    Energy Technology Data Exchange (ETDEWEB)

    Iracane, D.; Yvon, P. [CEA Saclay, Dir. de l' Energie Nucleaire, 91 - Gif sur Yvette (France)

    2007-07-01

    The creeping obsolescence of experimental irradiation reactors around the world, in the European Union in particular, means that the Jules Horowitz Reactor (JHR), due to be commissioned by CEA in 2014, at Cadarache, is an essential addition, whether it be for the investigation of materials, or of novel fuels. Its capabilities extend beyond the requirements of investigations relating to fourth-generation systems. (authors)

  9. Getting Smarter at Managing Avionic Software: The Results of a Two-Day Requirements Elicitation Workshop With DTAES

    Science.gov (United States)

    2007-10-01

    Charpentier, Robert; Salois, Martin; Bergeron, Jean; Debbabi, Mourad; Desharnais, Jules; Giasson, Emmanuel ; Ktari, Béchir; Michaud, Frédéric, and Tawbi...Security Establishment (CSE). Ottawa, Canada: (CSE). Read the PDF. 5. Shepard, Terry; Kelly, Diane; Smith, Ron; Chisholm, Ron; Jackson, Todd , and Mondoux

  10. Anmeldelse af: Afghantsy. The Russians in Afghanistan 1979-89

    DEFF Research Database (Denmark)

    Vestenskov, David

    2012-01-01

    Baseret på nyligt afklassificeret materiale fra arkiverne i Moskva samt fremstillinger af russiske historikere, tegnes et anderledes og mere nuanceret billede af de sovjetiske erfaringer fra Afghanistan. De første spadestik til opgøret med den amerikanske stempling af den sovjetiske ageren i jule...

  11. Combining Performance and Flexibility for RMS with a Hybrid Architecture

    NARCIS (Netherlands)

    Telgen, Daniël; Moergestel, Leo van; Puik, Erik; Muller, Pascal; Groenewegen, Arjan; Steen, Dick van der; Koole, Dennis; Wit, Patrick; Zanten, Arjan van; Meyer, John-Jules

    2013-01-01

    Author supplied Combining Performance and Flexibility for RMS with a Hybrid Architecture Dani¨el Telgen 12? , Leo van Moergestel 1 , Erik Puik 1 , Pascal Muller 1 , Arjan Groenewegen 1 , Dick van der Steen 1 , Dennis Koole 1 , Patrick de Wit 1 , Arjen van Zanten 1 , and John-Jules Meyer 2 1 Departm

  12. Katalog: Malerier, skulpturer, pasteller, tegninger

    DEFF Research Database (Denmark)

    Anderberg, Birgitte

    2011-01-01

    Tekster om Ordrupgaards samling af værker af Albert André, Anonym, Louis Anquetin, Antoine-Louis Barye, Eugène Boudin, Paul Cézanne, Camille Corot, Gustave Courbet, Thomas Couture, Charles-Francois Daubigny, Karl Daubigny, Honoré Daumier, Charles Despiiau, Diaz de la Peña, Jules Dupré, Théodore...

  13. Maine de Biran: The Relationship between the Physical and the Moral in Man

    NARCIS (Netherlands)

    Meacham, Darian

    2016-01-01

    Maine de Biran's work has had an enormous influence on the development of French Philosophy – Henri Bergson called him the greatest French metaphysician since Descartes and Malebranche, Jules Lachelier referred to him as the French Kant, and Royer-Collard called him simply 'the master of us all' – a

  14. What Is Steampunk, and Do I Want It in My Library?

    Science.gov (United States)

    Rozmus, Emily

    2011-01-01

    What is steampunk? Most call it Victorian science fiction. Steampunk can claim such authors as H.G. Wells and Jules Verne as its earliest writers. These two Victorian/Edwardian era writers created steampunk settings in books such as "The Time Machine" and "Journey to the Center of the Earth". In the 1990s, writers such as William Gibson, Bruce…

  15. Kirjandus ja vabamüürlus / Paavo Matsin

    Index Scriptorium Estoniae

    Matsin, Paavo, 1970-

    2009-01-01

    Loetletakse vabamüürlastest kirjanikke (pikemalt Jules Verne'ist, Gustav Meyrinkist, Rudyard Kiplingist ja Mait Metsanurgast) ning vabamüürlikke tegelasi või motiive kasutanud kirjanikke (Lev Tolstoi, Fjodor Dostojevski, Mihhail Bulgakov, Edgar Allan Poe)

  16. "Sugar" jõuab lavale / Ülle Hallik

    Index Scriptorium Estoniae

    Hallik, Ülle, 1963-

    2008-01-01

    Vanemuises esietendub 5. juunil "Sugar", lavastaja Mare Tommingas. Muusikal põhineb Jule Styne muusikalil "Sugar ehk Dzhässis ainult tüdrukud". Muusikali libreto kirjutas Peter Stone Robert Thoereni jutustuse ning Billy Wilderi ja I. A. L. Dimanondi filmi "Some Like It Hot" põhjal

  17. Detjam kapitana Granta privezli iz Ameriki bizonov i straussov / Margarita Golovanova

    Index Scriptorium Estoniae

    Golovanova, Margarita

    2006-01-01

    Kuidas "Mosfilmis" filmiti Jules Verne'i järgi mängufilmi "Kapten Granti lapsed" : režissöör Vladimir Vainshtok : helilooja Isaak Dunajevski : näitlejad Nikolai Tsherkassov, Jakov Segel : NSV Liit 1936

  18. "Does Broca's Area Exist?:" Christofredo Jakob's 1906 Response to Pierre Marie's Holistic Stance

    Science.gov (United States)

    Tsapkini, Kyrana; Vivas, Ana B.; Triarhou, Lazaros C.

    2008-01-01

    In 1906, Pierre Marie triggered a heated controversy and an exchange of articles with Jules Dejerine over the localization of language functions in the human brain. The debate spread internationally. One of the timeliest responses, that appeared in print 1 month after Marie's paper, came from Christofredo Jakob, a Bavarian-born neuropathologist…

  19. The Film. The Bobbs-Merrill Series in Composition and Rhetoric.

    Science.gov (United States)

    Sarris, Andrew, Ed.

    Prefaced by a brief discussion of early films and film criticism, 10 essays treat selected modern directors and their works. Essays on Stanley Kubrick's "Lolita," the early works of Elia Kazan, and the response of French critics to Jerry Lewis explore the American scene, while Francois Truffaut's "Jules and Jim," the early work of Robert Bressen,…

  20. Academic Achievement, Pupil Participation and Integration of Group Work Skills in Secondary School Classrooms in Trinidad and Barbados

    Science.gov (United States)

    Layne, Anthony; Jules, Vena; Kutnick, Peter; Layne, Clarissa

    2008-01-01

    Studies have shown a positive relationship between a rise in schooling levels and economic production [World Bank, 2005. A Time to Choose: Caribbean Development in the 21st Century. World Bank, Washington, DC; Jules, V., Panneflek, A., 2000. EFA in the Caribbean: Assessment 2000, Sub-Regional Report, vol. 2, The State of Education in the Caribbean…

  1. Maine de Biran: The Relationship between the Physical and the Moral in Man

    NARCIS (Netherlands)

    Meacham, Darian

    2016-01-01

    Maine de Biran's work has had an enormous influence on the development of French Philosophy – Henri Bergson called him the greatest French metaphysician since Descartes and Malebranche, Jules Lachelier referred to him as the French Kant, and Royer-Collard called him simply 'the master of us all' –

  2. The Film. The Bobbs-Merrill Series in Composition and Rhetoric.

    Science.gov (United States)

    Sarris, Andrew, Ed.

    Prefaced by a brief discussion of early films and film criticism, 10 essays treat selected modern directors and their works. Essays on Stanley Kubrick's "Lolita," the early works of Elia Kazan, and the response of French critics to Jerry Lewis explore the American scene, while Francois Truffaut's "Jules and Jim," the early work of Robert Bressen,…

  3. "Sugar" jõuab lavale / Ülle Hallik

    Index Scriptorium Estoniae

    Hallik, Ülle, 1963-

    2008-01-01

    Vanemuises esietendub 5. juunil "Sugar", lavastaja Mare Tommingas. Muusikal põhineb Jule Styne muusikalil "Sugar ehk Dzhässis ainult tüdrukud". Muusikali libreto kirjutas Peter Stone Robert Thoereni jutustuse ning Billy Wilderi ja I. A. L. Dimanondi filmi "Some Like It Hot" põhjal

  4. Maine de Biran: The Relationship between the Physical and the Moral in Man

    NARCIS (Netherlands)

    Meacham, Darian

    2016-01-01

    Maine de Biran's work has had an enormous influence on the development of French Philosophy – Henri Bergson called him the greatest French metaphysician since Descartes and Malebranche, Jules Lachelier referred to him as the French Kant, and Royer-Collard called him simply 'the master of us all' – a

  5. Celebration Capitalism

    OpenAIRE

    Boykoff, Jules

    2014-01-01

    Capitalism is a nimble shapeshifter. In this talk Jules Boykoff draws from the history of the Olympic Games to offer a theory of “celebration capitalism,” a form of modern-day economics that complements Naomi Klein’s “disaster capitalism” marked by neoliberalism: privatization, deregulation, and free-market rhetoric.

  6. Evaluation of modelled methane emissions over northern peatland sites

    Science.gov (United States)

    Gao, Yao; Burke, Eleanor; Chadburn, Sarah; Raivonen, Maarit; Susiluoto, Jouni; Vesala, Timo; Aurela, Mika; Lohila, Annalea; Aalto, Tuula

    2017-04-01

    Methane (CH4) is a powerful greenhouse gas, with approximately 34 times the global warming potential of carbon dioxide (CO2) over a century time horizon (IPCC, 2013). The strong sensitivity of methane emissions to environmental factors has led to concerns about potential positive feedbacks to climate change. Evaluation of the ability of the process-based land surface models of earth system models (ESMs) in simulating CH4 emission over peatland is needed for more precise future predictions. In this study, two peatland sites of poor and rich soil nutrient conditions, in southern and northern Finland respectively, are adopted. The measured CH4 fluxes at the two sites are used to evaluate the CH4 emissions simulated by the land surface model (JULES) of the UK Earth System model and by the Helsinki peatland methane emission model (HIMMELI), which is developed at Finnish Meteorological Institute and Helsinki University. In JULES, CH4 flux is simply related to soil temperature, wetland fraction and effective substrate availability. However, HIMMELI has detailed descriptions of microbial and transport processes for simulating CH4 flux. The seasonal dynamics of CH4 fluxes at the two sites are relatively well captured by both models, but model biases exist. Simulated CH4 flux is sensitive to water table depth (WTD) at both models. However, the simulated WTD is limited to be below ground in JULES. It is also important to have the annual cycle of LAI correct when coupling JULES with HIMMELI.

  7. Towards a simple representation of chalk hydrology in land surface modelling

    Science.gov (United States)

    Rahman, Mostaquimur; Rosolem, Rafael

    2017-01-01

    Modelling and monitoring of hydrological processes in the unsaturated zone of chalk, a porous medium with fractures, is important to optimize water resource assessment and management practices in the United Kingdom (UK). However, incorporating the processes governing water movement through a chalk unsaturated zone in a numerical model is complicated mainly due to the fractured nature of chalk that creates high-velocity preferential flow paths in the subsurface. In general, flow through a chalk unsaturated zone is simulated using the dual-porosity concept, which often involves calibration of a relatively large number of model parameters, potentially undermining applications to large regions. In this study, a simplified parameterization, namely the Bulk Conductivity (BC) model, is proposed for simulating hydrology in a chalk unsaturated zone. This new parameterization introduces only two additional parameters (namely the macroporosity factor and the soil wetness threshold parameter for fracture flow activation) and uses the saturated hydraulic conductivity from the chalk matrix. The BC model is implemented in the Joint UK Land Environment Simulator (JULES) and applied to a study area encompassing the Kennet catchment in the southern UK. This parameterization is further calibrated at the point scale using soil moisture profile observations. The performance of the calibrated BC model in JULES is assessed and compared against the performance of both the default JULES parameterization and the uncalibrated version of the BC model implemented in JULES. Finally, the model performance at the catchment scale is evaluated against independent data sets (e.g. runoff and latent heat flux). The results demonstrate that the inclusion of the BC model in JULES improves simulated land surface mass and energy fluxes over the chalk-dominated Kennet catchment. Therefore, the simple approach described in this study may be used to incorporate the flow processes through a chalk unsaturated

  8. Comparison of the HadGEM2 climate-chemistry model against in situ and SCIAMACHY atmospheric methane data

    Directory of Open Access Journals (Sweden)

    G. D. Hayman

    2014-12-01

    Full Text Available Wetlands are a major emission source of methane (CH4 globally. In this study, we evaluate wetland emission estimates derived using the UK community land surface model (JULES, the Joint UK Land Earth Simulator against atmospheric observations of methane, including, for the first time, total methane columns derived from the SCIAMACHY instrument on board the ENVISAT satellite. Two JULES wetland emission estimates are investigated: (a from an offline run driven with Climatic Research Unit–National Centers for Environmental Prediction (CRU-NCEP meteorological data and (b from the same offline run in which the modelled wetland fractions are replaced with those derived from the Global Inundation Extent from Multi-Satellites (GIEMS remote sensing product. The mean annual emission assumed for each inventory (181 Tg CH4 per annum over the period 1999–2007 is in line with other recently published estimates. There are regional differences as the unconstrained JULES inventory gives significantly higher emissions in the Amazon (by ~36 Tg CH4 yr−1 and lower emissions in other regions (by up to 10 Tg CH4 yr−1 compared to the JULES estimates constrained with the GIEMS product. Using the UK Hadley Centre's Earth System model with atmospheric chemistry (HadGEM2, we evaluate these JULES wetland emissions against atmospheric observations of methane. We obtain improved agreement with the surface concentration measurements, especially at high northern latitudes, compared to previous HadGEM2 runs using the wetland emission data set of Fung et al. (1991. Although the modelled monthly atmospheric methane columns reproduce the large-scale patterns in the SCIAMACHY observations, they are biased low by 50 part per billion by volume (ppb. Replacing the HadGEM2 modelled concentrations above 300 hPa with HALOE–ACE assimilated TOMCAT output results in a significantly better agreement with the SCIAMACHY observations. The use of the GIEMS product to constrain the JULES

  9. Comparison of the HadGEM2 climate-chemistry model against in-situ and SCIAMACHY atmospheric methane data

    Directory of Open Access Journals (Sweden)

    G. D. Hayman

    2014-05-01

    Full Text Available Wetlands are a major emission source of methane (CH4 globally. In this study, we have evaluated wetland emission estimates derived using the UK community land surface model (JULES, the Joint UK Land Earth Simulator against atmospheric observations of methane, including, for the first time, total methane columns derived from the SCIAMACHY instrument on board the ENVISAT satellite. Two JULES wetland emission estimates were investigated: (a from an offline run driven with CRU-NCEP meteorological data and (b from the same offline run in which the modelled wetland fractions were replaced with those derived from the Global Inundation Extent from Multi-Satellites (GIEMS remote sensing product. The mean annual emission assumed for each inventory (181 Tg CH4 per annum over the period 1999–2007 is in line with other recently-published estimates. There are regional differences as the unconstrained JULES inventory gave significantly higher emissions in the Amazon and lower emissions in other regions compared to the JULES estimates constrained with the GIEMS product. Using the UK Hadley Centre's Earth System model with atmospheric chemistry (HadGEM2, we have evaluated these JULES wetland emissions against atmospheric observations of methane. We obtained improved agreement with the surface concentration measurements, especially at northern high latitudes, compared to previous HadGEM2 runs using the wetland emission dataset of Fung (1991. Although the modelled monthly atmospheric methane columns reproduced the large–scale patterns in the SCIAMACHY observations, they were biased low by 50 part per billion by volume (ppb. Replacing the HadGEM2 modelled concentrations above 300 hPa with HALOE–ACE assimilated TOMCAT output resulted in a significantly better agreement with the SCIAMACHY observations. The use of the GIEMS product to constrain JULES-derived wetland fraction improved the description of the wetland emissions in JULES and gave a good description

  10. Comparison of the HadGEM2 climate-chemistry model against in situ and SCIAMACHY atmospheric methane data

    Science.gov (United States)

    Hayman, G. D.; O'Connor, F. M.; Dalvi, M.; Clark, D. B.; Gedney, N.; Huntingford, C.; Prigent, C.; Buchwitz, M.; Schneising, O.; Burrows, J. P.; Wilson, C.; Richards, N.; Chipperfield, M.

    2014-12-01

    Wetlands are a major emission source of methane (CH4) globally. In this study, we evaluate wetland emission estimates derived using the UK community land surface model (JULES, the Joint UK Land Earth Simulator) against atmospheric observations of methane, including, for the first time, total methane columns derived from the SCIAMACHY instrument on board the ENVISAT satellite. Two JULES wetland emission estimates are investigated: (a) from an offline run driven with Climatic Research Unit-National Centers for Environmental Prediction (CRU-NCEP) meteorological data and (b) from the same offline run in which the modelled wetland fractions are replaced with those derived from the Global Inundation Extent from Multi-Satellites (GIEMS) remote sensing product. The mean annual emission assumed for each inventory (181 Tg CH4 per annum over the period 1999-2007) is in line with other recently published estimates. There are regional differences as the unconstrained JULES inventory gives significantly higher emissions in the Amazon (by ~36 Tg CH4 yr-1) and lower emissions in other regions (by up to 10 Tg CH4 yr-1) compared to the JULES estimates constrained with the GIEMS product. Using the UK Hadley Centre's Earth System model with atmospheric chemistry (HadGEM2), we evaluate these JULES wetland emissions against atmospheric observations of methane. We obtain improved agreement with the surface concentration measurements, especially at high northern latitudes, compared to previous HadGEM2 runs using the wetland emission data set of Fung et al. (1991). Although the modelled monthly atmospheric methane columns reproduce the large-scale patterns in the SCIAMACHY observations, they are biased low by 50 part per billion by volume (ppb). Replacing the HadGEM2 modelled concentrations above 300 hPa with HALOE-ACE assimilated TOMCAT output results in a significantly better agreement with the SCIAMACHY observations. The use of the GIEMS product to constrain the JULES-derived wetland

  11. Integrating hydrology within a fully coupled environmental prediction system

    Science.gov (United States)

    Best, Martin; Lewis, Huw; Ashton, Heather; Blyth, Eleanor; Martinez, Alberto

    2017-04-01

    Historically the hydrological community and the community developing the land surface component of atmospheric models have both been tasked with representing the terrestrial hydrological cycle, but have focused on different ends, namely streamflow and evaporation respectively. To date the lack of computational resources and representative observations have limited the integration of the skills within these two communities. However, this is no longer the case. In addition, the drive toward fully integrated high resolution environmental prediction systems, coupling atmosphere, land and ocean on regional domains, requires an accurate representation for all aspects of terrestrial hydrology. Hence a new focus is emerging to integrate improved hydrological processes within the land surface components of atmospheric models. The UK Environmental Prediction (UKEP) project is a research experiment aimed at understanding the potential benefits for detailed environmental forecasting from a fully coupled atmosphere/land/ocean system at km-scale resolution for the UK. The prototype model utilises the Joint UK Land Environment Simulator (JULES) as its land surface component, coupled to the RFM river flow model. Although JULES has been previously used for climate studies that close the global water cycle, the JULES/RFM system has not been comprehensively evaluated for its ability to simulate river discharge. In this study we attempt some initial evaluation of the JULES/RFM system for all aspects of the terrestrial hydrological cycle, including evaporation, soil moisture and streamflow. In addition, comparisons are made between the results from the fully coupled environmental prediction system and stand alone JULES/RFM simulations forced by atmospheric driving data from the UK weather forecasting model. This provides an opportunity to assess the impact of fully coupled versus a one way coupled response for terrestrial hydrology. Finally we consider the potential for coupling JULES

  12. 《低俗小说》

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    最经典的场景、最生动的对白、最地道的表达,尽在“影视对白”。跟着明星学英语,let’s go!本期影片:《低俗小说》。 Pulp Fiction (1994) is an American film directed by Quentin Tarantino. It stars John Travolta, Samuel Jackson, Uma Thurman and Bruce Willis. The film tells three separate (but loosely connected) stories which are set in the criminal underworld of Los Angeles. One of these stories follows Vincent Vega (Travolta) and Jules Winnfield (Jackson), two hit men for a powerful LA gangster. In this scene, Vincent and Jules are discussing Vincent' s recent trip to Europe.

  13. París en el siglo XX según Julio Verne

    OpenAIRE

    Diego, Rosa de

    1995-01-01

    L'objet de cet article est l'analyse du roman de Jules Verne "Paris au XX siècle", écrit en 1863 et inédit jusqu'a 1994. Il s'agit d'un roman d'imagination scientifique parce qu'il décrit et anticipe, avec une exactitude surprenante, comment sera Paris pendant la deuxieme moitié du XX siècle, sous un point de vue urbanistique, technologique, économique et social. Jules Verne apparait également comme un écrivain philosophe, avec une vision péssimiste du progrès de la civilisation et de la soli...

  14. El Bovarysmo // The Bovarysm

    Directory of Open Access Journals (Sweden)

    Mario Elkin Ramírez

    2011-12-01

    Full Text Available Luego de un breve recorrido por una sucinta historia del amor, se encuentra el lugar revolucionario que la obra de Gustave Flaubert constituyó como nuevo paradigma del amor y de la feminidad. Se retoman a continuación las formulaciones de Jules de Gaultier, quien introdujo el término de Bovarysmo en la psiquiatría, para, finalmente, mostrar el destino de esa noción en el psicoanálisis lacaniano. // After a short pass through a brief love story, Gustave Flaubert work that constituted a new love and femininity paradigm found a revolutionary place. Jules de Gaultier formulations where the Bovarysme term was introduced in psychiatry are restudy to show this notion destiny in the Lacanian psychoanalysis.

  15. París en el siglo XX según Julio Verne

    OpenAIRE

    Diego, Rosa de

    1995-01-01

    L'objet de cet article est l'analyse du roman de Jules Verne "Paris au XX siècle", écrit en 1863 et inédit jusqu'a 1994. Il s'agit d'un roman d'imagination scientifique parce qu'il décrit et anticipe, avec une exactitude surprenante, comment sera Paris pendant la deuxieme moitié du XX siècle, sous un point de vue urbanistique, technologique, économique et social. Jules Verne apparait également comme un écrivain philosophe, avec une vision péssimiste du progrès de la civilisation et de la soli...

  16. Impact of land cover changes on the South African climate

    Energy Technology Data Exchange (ETDEWEB)

    Ngwana, T I [South African Weather Service, Pretoria (South Africa); Demory, M-E; Vidale, P L; Plant, R S [University of Reading, Earley Gate, Reading (United Kingdom); Mbedzi, M P, E-mail: isaac.ngwana@weathersa.co.z [Eskom Holdings, Cleveland (South Africa)

    2010-08-15

    The Joint UK Land Environmental Simulator (JULES) was run offline to investigate the sensitivity of land surface type changes over South Africa. Sensitivity tests were made in idealised experiments where the actual land surface cover is replaced by a single homogeneous surface type. The vegetation surface types on which some of the experiments were made are static. Experimental tests were evaluated against the control. The model results show among others that the change of the surface cover results in changes of other variables such as soil moisture, albedo, net radiation and etc. These changes are also visible in the spin up process. The model shows different surfaces spinning up at different cycles. Because JULES is the land surface model of Unified Model, the results could be more physically meaningful if it is coupled to the Unified Model.

  17. Contribuições da psiquiatria clássica ao diagnóstico da melancolia: o delírio de negação e o delírio de indignidade

    Directory of Open Access Journals (Sweden)

    Maria de Fátima Ferreira

    2008-09-01

    Full Text Available Discute-se a respeito da importância que teve a pesquisa empreendida pelos psiquiatras franceses Jules Cotard e Jules Séglas nas primeiras elaborações freudianas acerca da melancolia. No esforço feito por Freud em distinguir as afecções psíquicas, ele leva em consideração os principais conceitos destacados pela psiquiatria clássica: a dor moral, condição para o delírio de indignidade, o mecanismo de auto-acusação e a hemorragia de libido. Busca-se uma articulação entre esses autores. Neste artigo essa retomada é importante para um aprimoramento no diagnóstico da melancolia. Constata-se que a melancolia na contemporaneidade nos remete não somente aos clássicos, mas sobretudo a Freud, em seus primeiros rascunhos.

  18. A Glimpse of the Future: The 62nd PTTI Systems & Applications Meeting November 2030

    Science.gov (United States)

    2009-11-01

    FORECASTING Though seeing into the future is difficult, some people have been able to forecast tomorrow’s technology with amazing accuracy. Jules ... Verne wrote about manned flight to the moon from a launch base in Florida in 1865 [1], and Arthur C. Clarke described the use of communications...Precise Time – William Cashin and Qinghua Wang Relativity in Everyday Systems – Aaron Dahlen. REFERENCES [1] J. Verne , 1865, From the Earth

  19. ATV ahoy - final preparations for the first flight of Europe's Space Ferry

    Science.gov (United States)

    Ellwood, John; Clervoy, Jean-François; Castel, Frederic

    2007-05-01

    Jules Verne, the first of five Automated Transfer Vehicles (ATVs), stands on the brink of flight. Its inaugural mission, set for the second half of 2007, will conclude an extensive 3-year test campaign. During the coming crucial months, the programme faces three key objectives: prepare for flight, finetune the interfaces with the International Space Station and the ISS partners, and ready Ariane-5 for launching its largest payload to date.

  20. Networking the Global Maritime Partnership

    Science.gov (United States)

    2008-06-01

    OEF TASKING FS AIGLE (MHC) FS DAGUE (LCT) FS D’ENTRECASTEAUX (AGS) FS FLOREAL (FFG) FS ISARD (AG) FS JULES VERNE (AD) FS LA LAVALLEE (FFG) FS LOIRE...from Galdorisi notes transcription). 25 Rodger, presentation to King-Hall. 26 Former CNO, Admiral Vern Clark described FORCEnet as an...weapons into a networked, distributed combat force.” Admiral Vern Clark, “Sea Power 21: Projecting Decisive Joint Capabilities,” United States

  1. Perchlorate Destruction and Potable Water Production Using Membrane Biofilm Reduction and Membrane Filtration

    Science.gov (United States)

    2013-11-18

    Owner David Friese APTwater APTwater 2516 Verne Roberts Circle, Suite H-102 Antioch, CA 94509 Phone 562-661-4999 X612 Cell 925-708-0480...Email dfriese@aptwater.com Project Manager Ryan Overstreet APTwater 2516 Verne Roberts Circle, Suite H-102 Antioch, CA 94509 Phone 562-661... Julee M. From: Arucan, Clyde Sent: Monday, August 22, 2011 1:20 PM To: Evans, Patrick; Berokoff, Daniel; Smith, Jennifer L. Cc: David Friese; Ryan

  2. Revising Hydrology of a Land Surface Model

    Science.gov (United States)

    Le Vine, Nataliya; Butler, Adrian; McIntyre, Neil; Jackson, Christopher

    2015-04-01

    Land Surface Models (LSMs) are key elements in guiding adaptation to the changing water cycle and the starting points to develop a global hyper-resolution model of the terrestrial water, energy and biogeochemical cycles. However, before this potential is realised, there are some fundamental limitations of LSMs related to how meaningfully hydrological fluxes and stores are represented. An important limitation is the simplistic or non-existent representation of the deep subsurface in LSMs; and another is the lack of connection of LSM parameterisations to relevant hydrological information. In this context, the paper uses a case study of the JULES (Joint UK Land Environmental Simulator) LSM applied to the Kennet region in Southern England. The paper explores the assumptions behind JULES hydrology, adapts the model structure and optimises the coupling with the ZOOMQ3D regional groundwater model. The analysis illustrates how three types of information can be used to improve the model's hydrology: a) observations, b) regionalized information, and c) information from an independent physics-based model. It is found that: 1) coupling to the groundwater model allows realistic simulation of streamflows; 2) a simple dynamic lower boundary improves upon JULES' stationary unit gradient condition; 3) a 1D vertical flow in the unsaturated zone is sufficient; however there is benefit in introducing a simple dual soil moisture retention curve; 4) regionalized information can be used to describe soil spatial heterogeneity. It is concluded that relatively simple refinements to the hydrology of JULES and its parameterisation method can provide a substantial step forward in realising its potential as a high-resolution multi-purpose model.

  3. The research reactors their contribution to the reactors physics; Les reacteurs de recherche leur apport sur la physique des reacteurs

    Energy Technology Data Exchange (ETDEWEB)

    Barral, J.C. [Electricite de France (EDF), 75 - Paris (France); Zaetta, A. [CEA/Cadarache, Direction des Reacteurs Nucleaires, DRN, 13 - Saint-Paul-lez-Durance (France); Johner, J. [CEA/Cadarache, Dept. de Recherches sur la Fusion Controlee (DRFC), 13 - Saint Paul lez Durance (France); Mathoniere, G. [CEA/Saclay, DEN, 91 - Gif sur Yvette (France)] [and others

    2000-07-01

    The 19 october 2000, the french society of nuclear energy organized a day on the research reactors. This associated report of the technical session, reactors physics, is presented in two parts. The first part deals with the annual meeting and groups general papers on the pressurized water reactors, the fast neutrons reactors and the fusion reactors industry. The second part presents more technical papers about the research programs, critical models, irradiation reactors (OSIRIS and Jules Horowitz) and computing tools. (A.L.B.)

  4. The Nobel Prize laureate - father of anaphylaxis Charles-Robert Richet (1850-1935) and his anticancerous serum.

    Science.gov (United States)

    Androutsos, G; Karamanou, M; Stamboulis, E; Liappas, I; Lykouras, E; Papadimitriou, G N

    2011-01-01

    Professor of physiology Charles-Robert Richet, winner of the Nobel Prize in 1913, is best known for his work on anaphylaxis. However, with his collaborator Jules Héricourt studied the effects of antibody treatment and made the very first attempts to fight cancer with serotherapy. Being versatile, Richet contributed in neurology, psychology and was also a poet, playwrighter, pacifist and pioneer in aviation.

  5. La survivance de Michelet : Historiographie et politique en France depuis 1870

    NARCIS (Netherlands)

    Creyghton, C.M.H.G.

    2016-01-01

    Après sa mort, l’historien Jules Michelet (1798-1874) a été érigé en historien national canonique dans la mémoire collective française. En même temps qu’il est devenu un auteur classique pour les historiens, il est invoqué et célébré aussi dans le domaine politique. La commémoration nationale de son

  6. The fabulous legacy of a Nobel Prize Laureate: Ralph M. Steinman, 1943-2011

    OpenAIRE

    Zitvogel, Laurence; Merad, Miriam; Kroemer, Guido

    2012-01-01

    The Nobel Prize in Physiology or Medecine 2011 was awarded to Ralph M. Steinman, Jules A. Hoffman and Bruce A. Beutler for the discovery of essential elements of innate immunity, in particular dendritic cells (DCs) and toll-like receptors (TLRs). Antigens become immunogenic and capable of triggering an adaptive immune response involving antigen-specific, MHC- restricted effector T cells, only if they are captured and presented by “accessory” cells. In 1972, Ralph M. Steinman and Zanvil Cohn i...

  7. The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration

    OpenAIRE

    Evans, Keith; Law, Simon; Walt, John; Buchholz, Patricia; Hansen,

    2009-01-01

    Keith Evans1, Simon K Law2, John Walt3, Patricia Buchholz4, Jan Hansen31Global Health Outcomes, Wolters Kluwer Health, Chester, United Kingdom; 2Jules Stein Eye Institute, Los Angeles, CA, USA; 3Global Health Outcomes Strategy and Research, Allergan Inc., Irvine, CA, USA; 4Health Economics, Pricing, and Reimbursement, Allergan GmbH, Ettlingen, GermanyPurpose: It is well accepted that conditions that cause central vision loss (CVL) have a negative impact on functional ability and quality of li...

  8. An operational framework for equity in the 2015 agreement

    CSIR Research Space (South Africa)

    Ngwadla, Xolisa

    2014-01-01

    Full Text Available /entries/justice- distributive/>. Coleman, Jules and Mendlow, Gabriel, "Theories of Tort Law", The Stanford Encyclopedia of Philosophy (Fall 2010 Edition), Edward N. Zalta (ed.), URL =

  9. Viis värvikat visiooni / Tanel Veenre

    Index Scriptorium Estoniae

    Veenre, Tanel, 1977-

    2009-01-01

    Eesti Kunstiakadeema lõputööde näitus "Tase'09" Rüütelkonna hoones Toompeal 21. juunini. Arhitekt Martin Voltri Tartu linnujaama projektist. Madis Nurmsi lavakujundusest ja -kostüümidest Jules Massenet' ooperile "Thais", mis esietendus 22. mail Pärnu Endlas. Klaasikunstnik Merle Bukoveci sisepurskkaevude seeriast "Voolujooned". Tootedisainer Pent Talveti magistritööst. Uku-Kristjan Küttise tehtud kirjatüübist

  10. World Tour

    CERN Multimedia

    Tauxe,H

    H.C.Tauxe est Dr.ès lettres de l'Université de Lausanne et a enseigné la philosophie jusqu'en 1962. Ensuite il s'est tourné vers le journalisme, et dans ce cadre il a fait le voyage, qui sera le thème de sa conférence, en suivant ce qui a écrit Jules Verne.

  11. Rationality problem of three-dimensional monomial group actions

    CERN Document Server

    Hoshi, Akinari; Yamasaki, Aiichi

    2009-01-01

    Let $K$ be a field of characteristic not two and $K(x,y,z)$ the rational function field over $K$ with three variables $x,y,z$. Let $G$ be a finite subgroup of $\\mathrm{GL}(3,\\bZ)$ acting on $K(x,y,z)$ by monomial $K$-automorphisms. We consider the rationality problem of the fixed field $K(x,y,z)^G$ under monomial actions of $G$. Namely whether $K(x,y,z)^G$ is rational (= purely transcendental) over $K$ or not. The problem is determined up to conjugacy in $\\mathrm{GL}(3,\\bZ)$, and there are 73 conjugacy classes of $G$ in $\\mathrm{GL}(3,\\bZ)$. By results of Endo-Miyata, Voskresenski\\u\\i, Lenstra, Saltman, Kang and Yamasaki, 8 conjugacy classes of 2-groups in $\\mathrm{GL}(3,\\bZ)$ have negative answers to the problem under certain monomial actions over some base field $K$, and the necessary and sufficient condition for the rationality of $K(x,y,z)^G$ over $K$ is given. In this paper, we show that the fixed field $K(x,y,z)^G$ under monomial actions of $G$ is rational over $K$ except for possibly negative 8 cases o...

  12. Graafikatriennaali grand prix Korea kunstnikule

    Index Scriptorium Estoniae

    1998-01-01

    Tallinna XI graafikatriennaali rahvusvaheline žürii andis grand prix korea kunstnikule Chung¡Sang-Gonile, kolm võrdset preemiat - soome kunstnikele Anita Jensenile ja Tapani Mikkonenile ning jaapani kunstnikule Estuko Obatale. Eesti Kunstimuuseumi preemia - Wendy Swallow. Tallinna linna preemia ja Ivar Luki sponsoripreemia - Walter Jule. Sponsoripreemiad : Paletti Eesti AS preemia - Inga Heamägi; Rannila Profiili preemia - Mojca Zlokarnik; UNDP preemia - Andrea Juan. Rotermanni soolalao arhitektuuri- ja kunstikeskuse diplom - Lis Ingram, Heli Päivikki Kurunsaari, Randi Strand, Wendy Swallow

  13. Bibliography for Advancement Study.

    Science.gov (United States)

    1987-07-01

    Uses, NAVEDTRA 10085-BI 1L SW 3&2, NAVEDTRA 10653-Fl -- Chaps 5, 8, 9, 0 10, 14, 15, and 16 Principles of Automotive Vehicles, TM 9-8000 Navy Driver’s...000 Chap 083, Allowances, Issues, Expeditures of ,.~ Material and Repair Parts, NAVSEA S9086-CS-STM-000 ~. ENCS (EN3, EN2, ENi, AND ENC BIBLIOGRAPHIES...TRAININ SERIES ____ M, JULE TITLE NAVEDTRA N’ir %,% %. %𔃻 Introduction to MPatter, Energy , and Direct Current %17Z-31-30-79 0507-Li- - {jCC-ECC

  14. [Obsessions before Freud: history and clinical practice].

    Science.gov (United States)

    Huertas, Rafael

    2014-01-01

    The article analyses the significance of the concept of "obsession" in nineteenth-century alienism. From a clinical point of view, Esquirol's description was completed by other authors (Jules Falret, Legrand du Saulle). In the area of psychopathological studies, French alienism, with Morel's emotional delirium or Janet's psychasthenia, defended the emotional theory, as opposed to the intellectual disorder proposed by German doctors. Lastly, the importance of the cultural framework is stressed in the appearance of obsessive symptoms and their interpretation. Along these lines, the article discusses the relationship of religious scruples to melancholy or the appearance of diagnostic categories subject to fin de siècle codes and mentalities.

  15. Orbital Debris Quarterly News. Volume 13; No. 1

    Science.gov (United States)

    Liou, J.-C. (Editor); Shoots, Debi (Editor)

    2009-01-01

    Topics discussed include: new debris from a decommissioned satellite with a nuclear power source; debris from the destruction of the Fengyun-1C meteorological satellite; quantitative analysis of the European Space Agency's Automated Transfer Vehicle 'Jules Verne' reentry event; microsatellite impact tests; solar cycle 24 predictions and other long-term projections and geosynchronus (GEO) environment for the Orbital Debris Engineering Model (ORDEM2008). Abstracts from the NASA Orbital Debris Program Office, examining satellite reentry risk assessments and statistical issues for uncontrolled reentry hazards, are also included.

  16. Electrical futures past.

    Science.gov (United States)

    Gooday, Graeme J N

    2005-12-01

    Futurist writing about technology emerged in the late 19th century at the same time as new kinds of electrical technology were making utopian futures seem practically attainable. Electrical writers and novelists alike thus borrowed from the popular "science" fiction of Jules Verne, Edward Bellamy and others to try to create self-fulfilling prophecies of a future in which electrical gadgets and machines met all major practical needs of civilization. To the extent that many parts of our world are populated by the hardware that they forecast, they succeeded in their goal.

  17. 激情,穿越时空雪铁龙新东方之旅巴黎行

    Institute of Scientific and Technical Information of China (English)

    国舜

    2011-01-01

    安德烈·雪铁龙尊崇两个人:一个是Gustave EIFFEL——他修造了埃菲尔铁塔,另一个是Jules VERNE——他写了著名的小说《八十天环游地球》。这两个人“一个知道如何去梦想,一个知道如何去实现”,可能这就是雪铁龙品牌被赋予的双重内涵吧。

  18. Librarians are vicious monsters, but canalso recommend a good read : En analys av alternativa bibliotekarieframställningar iscience fiction-litteratur

    OpenAIRE

    Österman Solborg, Amanda

    2014-01-01

    Uppsatsens syfte är att studera framställningar av manliga bibliotekarier i science fiction-litteratur, analysera vad dessa framställningar förmedlar för föreställningar om bibliotek och biblioteksverksamhet, samt att analysera de manliga bibliotekariernas koppling till maskuliniteter. Titlarna som analyseras är fyra romaner; Audrey Niffeneggers Tidsresenärens hustru, Dmitrij Gluchovskijs Metro 2033, Jules Vernes Paris i tjugonde seklet, och Jasper Ffordes Uppslukad – En fängslande historia o...

  19. Poe e a contemporaneidade: um coração sempre delator

    OpenAIRE

    Amodeo, Maria Tereza

    2009-01-01

    The work of Poe has been widely used by moviemakers since the beginning of the new art. The interface between literature and film is considered a controversial matter in contemporary culture, especially in relation to Poe’s work. The analysis of the literary elements of the short story “The tell-tale heart” guides the study of the name sake film adaptation of 1941 by Jules Dassin and the animation made by UPA (United Productions of America) in 1953. Besides the possibility of understanding th...

  20. [Henri Moissn, first French Nobel prize winner in chemistry: the man, the picture collector].

    Science.gov (United States)

    Viel, C

    1999-03-01

    Born in Paris in September 1852, Henri Moisson died in February 1907, two months after receiving the Nobel prize for chemistry. After a short schooling at Meaux college, he was destined to be a clock maker. He owes his vocation for chemistry to Jules Plicque, a chemist and friend at the college. Henri Moisson attended Fremy's school of chemistry at the Paris Natural History Museum and undertook pharmaceutical studies. In this presentation, we take a look at Henri Moissan's child-hood and teenage years, his scientific education and offer a glimpse of the man and the picture collector.

  1. Graafikatriennaali grand prix Korea kunstnikule

    Index Scriptorium Estoniae

    1998-01-01

    Tallinna XI graafikatriennaali rahvusvaheline žürii andis grand prix korea kunstnikule Chung¡Sang-Gonile, kolm võrdset preemiat - soome kunstnikele Anita Jensenile ja Tapani Mikkonenile ning jaapani kunstnikule Estuko Obatale. Eesti Kunstimuuseumi preemia - Wendy Swallow. Tallinna linna preemia ja Ivar Luki sponsoripreemia - Walter Jule. Sponsoripreemiad : Paletti Eesti AS preemia - Inga Heamägi; Rannila Profiili preemia - Mojca Zlokarnik; UNDP preemia - Andrea Juan. Rotermanni soolalao arhitektuuri- ja kunstikeskuse diplom - Lis Ingram, Heli Päivikki Kurunsaari, Randi Strand, Wendy Swallow

  2. Lapsed ei pea kannatama / Siiri Oviir

    Index Scriptorium Estoniae

    Oviir, Siiri, 1947-

    2008-01-01

    Ilmunud ka: Kesknädal 3. sept. lk. 5, Võrumaa Teataja, Koit 4. sept. lk. 2,6, Oma Saar 5. sept., lk. 5, Pärnu Postimees 5. sept., lk. 15, Virumaa Teataja 5. sept. lk. 11, Põhjarannik, Severnoje Poberezhje 6. sept. lk. 4, Valgamaalane 9. sept. lk. 2, Nädalaleht 12. sept. lk. 3. Rühm Europarlamendi liikmeid eesotsas Jules Maateniga algatasid üleeuroopalise allkirjade kogumise kampaania "Ütle ei!", kaitsmaks lapsi vägivalla, eriti seksuaalse vägivalla eest

  3. Neurosyphilitics and madmen: The French fin-de-siècle fictions of Huysmans, Lermina, and Maupassant.

    Science.gov (United States)

    Goulet, Andrea

    2013-01-01

    This chapter considers a neurological approach to analyzing the decadent and fantastic fictions of the French fin-de-siècle. It focuses on three texts whose depictions of male nervosism were influenced by Charles Baudelaire's biography of Edgar Allan Poe and by contemporary medical discourses, including those of Jean-Martin Charcot and George Miller Beard: Joris-Karl Huysmans' À Rebours (1884), Jules Lermina's Les Fous (1885), and Guy de Maupassant's Le Horlà (1885-1887). Although these authors were philosophically antipositivist and antimaterialist, they used scientific theories of neurasthenia, neurodegeneration, and visual hallucination to probe the frontiers between body and spirit, the known and the unknowable.

  4. Processi di visualizzazione poetica: descrizione e immaginazione nella critica di danza del XIX secolo

    Directory of Open Access Journals (Sweden)

    Christina Thurner

    2014-12-01

    Full Text Available This essay addresses the interest in the discourse of dance criticism within the French feuilleton of the 19th Century. It explores poetical techniques of writing with regard to and on examination of the perception of romantic ballet. The author of the essay argues that critics as Théophile Gautier and Jules Janin created and cultivated an emphatic style of criticism, which can be described as a transposition of the subjective view / imagination of the observer into poetic language. These discoursive practices became significant and paradigmatic – also in relation to the perception of dance till this day.

  5. U. S. Multinational Corporations and National Security Policy

    Science.gov (United States)

    1975-08-01

    aCle PjJ^y R<«eaiv-h Centre in Great Britain published in of Ln^r ^-T I chGm^ industry which provides an assessment ^L7 I \\^Ch/ree trade...Ojitions, Ihe Atlantic frade Study, Trade Foliey Research Centre , London, 1971 29 Jules Jir.ickman, The_EoonomlcH of the Chomtcal Industry. Manu...and President Nixon apparently agreed with President Pompidou at the Iceland summit that the decision would be reversed. Although most of the

  6. When the Patient Believes That the Organs Are Destroyed: Manifestation of Cotard’s Syndrome

    Directory of Open Access Journals (Sweden)

    Leonardo Machado

    2016-01-01

    Full Text Available Cotard’s Syndrome (CS is a rare clinical event described for the first time in 1880 by the neurologist and psychiatrist Jules Cotard and characterized by negation delusions (or nihilists. Immortality and hypochondriac delusions are also typical. Nowadays, it is known that CS can be associated with many neuropsychiatric conditions. In this article, we describe the case of a patient that believed not having more organs and having the body deformed and whose CS was associated with a bigger depressive disorder. Although the electroconvulsive therapy is the most described treatment modality in the literature, the reported case had therapeutic success with association of imipramine and risperidone.

  7. Raphaël Blanchard, parasitology, and the positioning of medical entomology in Paris.

    Science.gov (United States)

    Osborne, M A

    2008-12-01

    The histories of medical entomology and parasitology are entwined. Raphaël Blanchard (1857-1919), Chair of Medical Natural History and Parasitology at the Faculty of Medicine in Paris, organized the teaching of medical entomology and civilian colonial medicine. He also founded and edited the journal Archives de Parasitologie and started the Institute de Médecine Coloniale where he mentored many foreign students and researchers. Additionally, Blanchard is important for his scientific internationalism and medical historical work on the cultural location of parasitology and for training the future professors of parasitology Jules Guiart, Emile Brumpt, and Charles Joyeux.

  8. Introduction

    OpenAIRE

    Pellegrin, Nicole; BARD, Christine

    2003-01-01

    À chacune/chacun, son image de la fille en garçon, et la panoplie vestimentaire qui va avec : complet trois pièces, salopette, cuirasse, strass, smoking, perfecto, bloomer, pourpoint, monocle, lévite de bure, chevelures rases, musculatures gonflées... Qui n'a pas rêvé de Katherine Hepburn dans Sylvia Scarlett et de Greta Garbo en Christine de Suède, de Jeanne Moreau entre Jules et Jim, de Barbara Streisand jouant Yentl, de Sarah Bernhardt faisant l'Aiglon, sans parler d'héroïnes plus ...

  9. Charging of capacitors with double switch. The principle of operation of auto-zero and chopper-stabilized DC amplifiers

    CERN Document Server

    Yordanov, Vasil G; Manolev, Stojan G; Mishonov, Todor M

    2015-01-01

    The principle of operation of auto-zero and chopper-stabilized DC amplifiers, which is realized in many contemporary operational amplifiers is illustrated by a simple experimental setup given at the Open Experimental Physics Olympiad 2014 - "The Day of the Capacitor", held in Sofia and Gevgelija. The Olympiad was organized by the Sofia Branch of the Union of Physicists in Bulgaria and the Regional Society of Physicists of Strumica, Macedonia. In addition to the solution of the secondary school task in the paper is given a detailed engineering description of the patent by Edwin Goldberg and Jules Lehmann, Stabilized direct current amplifier, U.S. Patent 2,684,999 (1949).

  10. Nous remercions

    OpenAIRE

    2014-01-01

    Ruth Amossy Violaine Appel Aurélie Aubert Gloria Awad Julien Bertrand Aimé-Jules Bizimana Stephan Bratosin Philippe Braud Stéphane Cabrolié Dominique Cotte Alexandre Coutant Sébastien Couvrette Pierre De Senarciens Françoise Denoyelle Jean-Claude Deroubaix Guillaume Devin Jean-Pierre Esquenazi Patrick Eveno Sylvia Faure Jairo Ferreira François Foret Fanny Georges Laurent Gille Corinne Gobin Valérie Gorin Benoît Grevisse Jean Noël Kapferer Roselyne Koren Yves Krief Lylette Lacôte-Gabrysiak Pau...

  11. Bifurcations of Periodic Orbits and Invariant Sets in Piecewise Linear Dynamical Systems

    OpenAIRE

    Fernández García, Soledad

    2012-01-01

    This year is the 100th anniversary of the death of Jules Henri Poincaré (Nancy, France, 29 April 1854-Paris, France, 17 July 1912), the founding father of Dynamical Systems theory. In mathematics, he is known as The Last Universalist, since he excelled in all fields of the discipline during his life. As it is well-known, the motivation of part of his work was the Celestial Mechanics [82, 83] and more specifically, the three-body problem. Within these more than 100 years, the Dynamic...

  12. Australian wine consumers’ acceptance of and attitudes toward the use of additives in wine and food production

    Directory of Open Access Journals (Sweden)

    Saltman Y

    2015-11-01

    Full Text Available Yaelle Saltman, Trent E Johnson, Kerry L Wilkinson, Susan EP Bastian Department of Wine and Food, School of Agriculture, Food and Wine, The University of Adelaide, Waite Campus, Adelaide, SA, Australia. Abstract: Additives are routinely used in food and wine production to enhance product quality and/or prevent spoilage. Compared with other industries, the wine industry is only permitted to use a limited number of additives. Whereas flavor additives are often used to intensify the aroma and flavor of foods and beverages, the addition of flavorings to wine contravenes the legal definition of wine. Given the current legislation, it is perhaps not surprising that the potential use of food additives in wine production has not been explored. This study therefore investigated Australian wine consumers' acceptance of and attitudes toward the use of additives in food and wine production. Consumers (n=1,031 were segmented based on their self-reported wine knowledge (ie, subjective knowledge. Using these ratings, low (n=271, medium (n=528, and high (n=232 knowledge segments were identified. Consumers considered natural flavorings and colors, and additives associated with health benefits (eg, vitamins, minerals, and omega 3 fatty acids, to be acceptable food additives, irrespective of their level of wine knowledge. In contrast, the use of winemaking additives, even commonly used and legally permitted additives such as tartaric acid, preservatives, oak chips, and tannins, were considered far less acceptable, particularly, by less knowledgeable consumers. Surprisingly, natural flavorings were considered more acceptable than currently used winemaking additives. Consumers were therefore asked to identify the flavors they would most prefer in white and red wines. Fruit flavors featured prominently in consumer responses, eg, lemon and apple for white wines and blackcurrant and raspberry for red wines, but vanilla and/or chocolate, ie, attributes typically

  13. Non-Medical Uses of X–Rays

    Directory of Open Access Journals (Sweden)

    J. Jalal Shokouhi

    2005-08-01

    Full Text Available Introduction & Background: Deep and eminent pene-trance of x–ray, makes it useful and applicable in ra-diography and CT scanning of paintings, art pieces, ceramics, automummies, and even metal and glass objects especially in the field of archeology. In the world, 2 types of automummies have been described: ice-man and soap-man, whereas in Iran in addition to these, another rare kind of mummy namely salt-man, has also been discovered. Four salt-men have been identified till now. Patients & Methods: In winter of 1993, the first salt man was discovered. The first salt man's age was measured by carbon 14 to be 1700–1800 years which dates back to the powerful Sasanian emperor era ap-proximately 200 to 300 years before Islam. Radiogra-phy, 2D- and 3D-CT, high energy weighted spectros-copy, genetic analysis, microbiology and histology evaluations, carbon 14 studies, and DNA finger print-ing were done for him. Thin layer chromatography of his cloths colors, rare element assessment, archeol-ogy, metallurgy, and sociology investigations where also employed. Whereas the 2nd, 3rd, and 4th salt-men are under investigation by means of x-ray and CT scan the polymer specimen is under study to be syn-thesized by the S.L.A machine. Results: This investigation proposes the precious role of x-ray in radiology of artifacts, handicrafts and ar-cheology. Conclusion: In this way valuable museums are en-riched by cultural and historical remnants of previous powers and authority and this inspires the tourism industry with magnificent and splendid masterpieces of ancient civilizations. Preserving and recognizing them also helps to promote anthropological knowl-edge.

  14. INFERNO: a fire and emissions scheme for the UK Met Office's Unified Model

    Science.gov (United States)

    Mangeon, Stéphane; Voulgarakis, Apostolos; Gilham, Richard; Harper, Anna; Sitch, Stephen; Folberth, Gerd

    2016-08-01

    Warm and dry climatological conditions favour the occurrence of forest fires. These fires then become a significant emission source to the atmosphere. Despite this global importance, fires are a local phenomenon and are difficult to represent in large-scale Earth system models (ESMs). To address this, the INteractive Fire and Emission algoRithm for Natural envirOnments (INFERNO) was developed. INFERNO follows a reduced complexity approach and is intended for decadal- to centennial-scale climate simulations and assessment models for policy making. Fuel flammability is simulated using temperature, relative humidity (RH) and fuel load as well as precipitation and soil moisture. Combining flammability with ignitions and vegetation, the burnt area is diagnosed. Emissions of carbon and key species are estimated using the carbon scheme in the Joint UK Land Environment Simulator (JULES) land surface model. JULES also possesses fire index diagnostics, which we document and compare with our fire scheme. We found INFERNO captured global burnt area variability better than individual indices, and these performed best for their native regions. Two meteorology data sets and three ignition modes are used to validate the model. INFERNO is shown to effectively diagnose global fire occurrence (R = 0.66) and emissions (R = 0.59) through an approach appropriate to the complexity of an ESM, although regional biases remain.

  15. The impact of fires in the UK Met Office's Unified Model and the INFERNO interactive fire scheme

    Science.gov (United States)

    Mangeon, S.

    2015-12-01

    Forest fires are a key interaction between the land and the atmosphere. Yet this interaction is often omitted from Earth System Models. We will present the efforts carried out within the UK Met Office: for both its Unified Model (UM8.4) and land surface model (JULES). These efforts have focused on diagnosing fire occurrence and impact on composition. We will present the schemes used for diagnostic fire weather indices, and INFERNO (INteractive Fires and Emissions algoRithm for Natural envirOnments). INFERNO follows a reduced complexity approach and is intended for decadal to centennial scale climate simulations and assessment models for policy making. The scheme uses temperature, relative humidity, precipitation and soil moisture to simulate fuel flammability; once combined with ignitions, INFERNO diagnoses burnt area. Using JULES' carbon scheme, burnt area leads to fire emissions which are inputs to the model's chemistry and aerosol scheme (UKCA). We will show the coupled model performance in capturing burnt area and fire emissions and investigate the role of fires on atmospheric composition interannual variability (in particular CO, and aerosols).

  16. Land surface model performance using cosmic-ray and point-scale soil moisture measurements for calibration

    Science.gov (United States)

    Iwema, Joost; Rosolem, Rafael; Rahman, Mostaquimur; Blyth, Eleanor; Wagener, Thorsten

    2017-06-01

    At very high resolution scale (i.e. grid cells of 1 km2), land surface model parameters can be calibrated with eddy-covariance flux data and point-scale soil moisture data. However, measurement scales of eddy-covariance and point-scale data differ substantially. In our study, we investigated the impact of reducing the scale mismatch between surface energy flux and soil moisture observations by replacing point-scale soil moisture data with observations derived from Cosmic-Ray Neutron Sensors (CRNSs) made at larger spatial scales. Five soil and evapotranspiration parameters of the Joint UK Land Environment Simulator (JULES) were calibrated against point-scale and Cosmic-Ray Neutron Sensor soil moisture data separately. We calibrated the model for 12 sites in the USA representing a range of climatic, soil, and vegetation conditions. The improvement in latent heat flux estimation for the two calibration solutions was assessed by comparison to eddy-covariance flux data and to JULES simulations with default parameter values. Calibrations against the two soil moisture products alone did show an advantage for the cosmic-ray technique. However, further analyses of two-objective calibrations with soil moisture and latent heat flux showed no substantial differences between both calibration strategies. This was mainly caused by the limited effect of calibrating soil parameters on soil moisture dynamics and surface energy fluxes. Other factors that played a role were limited spatial variability in surface fluxes implied by soil moisture spatio-temporal stability, and data quality issues.

  17. The role of history in teaching science — A case study

    Science.gov (United States)

    Hendrick, Robert M.

    1992-06-01

    One of the most interesting aspects of late-nineteenth-century France was the extraordinary interest the public expressed in science. Its adulation of Pasteur was only one of the many manifestations of this interest. It was also expressed in the widespread popularity of scientists as public figures and in the increasing public and private financial support of science. While popularity of science was created in the general public by fiction and by the various international ‘world fairs’ held in Paris, it was strongest and most important in the middle classes. This paper examines one of the key methods used to stimulate bourgeois interest in science in France during the Second Empire and early Third Republic (1852 1895): the campaign to create a science vulgarisée, a popularized science. While a number of different approaches used by these popularizers are examined, the article concentrates on the ‘science writings’ of Jules Michelet and Jules Verne, both of whom were immensely successful in creating a favorable climate of opinion for French science. The article concludes by suggesting how such an approach could be modernized and utilized in order to create greater scientific literacy and a similar acceptance by the public today.

  18. Development and optimization of FJP tools and their practical verification

    Science.gov (United States)

    Messelink, Wilhelmus A. C. M.; Waeger, Reto; Meeder, Mark; Looser, Herbert; Wons, Torsten; Heiniger, Kurt C.; Faehnle, Oliver W.

    2005-09-01

    This article presents the recent achievements with Jules Verne, a sub-aperture polishing technique closely related to Fluid Jet Polishing [1]. Whereas FJP typically applies a nozzle stand-off distance of millimeters to centimeters, JV uses a stand-off distance down to 50 μm. The objective is to generate a non-directional fluid flow parallel to the surface, which is specifically suited to reduce the surface roughness [2, 3]. Different characteristic Jules Verne nozzle geometries have been designed and numerically simulated using Computational Fluid Dynamics (CFD). To verify these simulations, the flow of fluid and particles of these nozzles has been visualized in a measurement setup developed specifically for this purpose. A simplified JV nozzle geometry is positioned in a measurement setup and the gap between tool and surface has been observed by an ICCD camera. In order to be able to visualize the motion of the abrasives, the particles have been coated with fluorescence. Furthermore, these nozzles have been manufactured and tested in a practical environment using a modified polishing machine. The results of these laboratory and practical tests are presented and discussed, demonstrating that the CFD simulations are in good agreement with the experiments. It was possible to qualitatively predict the material removal on the processed glass surface, due to the implementation of appropriate erosion models [4, 5] in the CFD software.

  19. Tamoxifen in early-stage estrogen receptor-positive breast cancer: overview of clinical use and molecular biomarkers for patient selection

    Directory of Open Access Journals (Sweden)

    Carmen Criscitiello

    2010-12-01

    Full Text Available Carmen Criscitiello1, Debora Fumagalli1, Kamal S Saini2, Sherene Loi11Breast Cancer Translational Research Laboratory, Institut Jules Bordet, Université Libre de Bruxelles, Brussels; 2Breast Data Centre, Institut Jules Bordet, Brussels, BelgiumAbstract: Tamoxifen was the first targeted anticancer agent for breast cancer patients and its effects on reduction of breast cancer events and improvement in overall survival are undisputed. Hence, it has long been considered an essential part of patient care. Recent results of several large adjuvant hormonal trials evaluating the use of aromatase inhibitors in comparison with the previous standard of five years of tamoxifen has led to a paradigm shift, ensuring the inclusion of an aromatase inhibitor as part of standard endocrine therapy for most postmenopausal women diagnosed today with estrogen receptor-positive breast cancer. However, one could argue that despite statistically significant improvements in breast cancer events, an overall survival advantage has not been clear. In this review, we discuss recent genomic and molecular data pertaining to estrogen receptor-positive breast cancer and how this knowledge may aid clinicians to prescribe adjuvant hormonal treatment in the future. A combination of gene expression and genetic aberration markers may be most useful in discerning a population that is still appropriate for adjuvant tamoxifen treatment.Keywords: tamoxifen, aromatase inhibitors, resistance, prediction, mutation, endocrine therapy, PI3K

  20. The breakthrough in understanding immune response——introduction of Nobel Prize in Physiology or Medicine 2011%揭示免疫应答的关键环节——2011年诺贝尔生理学或医学奖简介

    Institute of Scientific and Technical Information of China (English)

    张婷; 王晓民

    2011-01-01

    The Nobel Prize in Physiology or Medicine 2011 is divided, with one half jointly to Bruce A. Beutler and Jules A. Hoffmann for their discoveries concerning the activation of innate immunity and the other half to Ralph M. Steinman for his discovery of the dendritic cell and its role in adaptive immunity. The detailed understanding of the immune system provided by the new Nobel laureates has given other researchers the ability to improve vaccines and to attempt to stimulate immune reactions to cancer and inflammation.%2011年诺贝尔生理学或医学奖颁发给分别来白法国、美国和加拿大的3位免疫学家Jules Hoffmann、Bruce Beutler和Ralph Steinman,以表彰他们对免疫应答包括先天免疫及获得性免疫中关键环节的揭示.他们的工作为疫苗改进,癌症及炎性反应的防治开辟了新的道路.

  1. Impact of model developments on present and future simulations of permafrost in a global land-surface model

    Science.gov (United States)

    Chadburn, S. E.; Burke, E. J.; Essery, R. L. H.; Boike, J.; Langer, M.; Heikenfeld, M.; Cox, P. M.; Friedlingstein, P.

    2015-08-01

    There is a large amount of organic carbon stored in permafrost in the northern high latitudes, which may become vulnerable to microbial decomposition under future climate warming. In order to estimate this potential carbon-climate feedback it is necessary to correctly simulate the physical dynamics of permafrost within global Earth system models (ESMs) and to determine the rate at which it will thaw. Additional new processes within JULES, the land-surface scheme of the UK ESM (UKESM), include a representation of organic soils, moss and bedrock and a modification to the snow scheme; the sensitivity of permafrost to these new developments is investigated in this study. The impact of a higher vertical soil resolution and deeper soil column is also considered. Evaluation against a large group of sites shows the annual cycle of soil temperatures is approximately 25 % too large in the standard JULES version, but this error is corrected by the model improvements, in particular by deeper soil, organic soils, moss and the modified snow scheme. A comparison with active layer monitoring sites shows that the active layer is on average just over 1 m too deep in the standard model version, and this bias is reduced by 70 cm in the improved version. Increasing the soil vertical resolution allows the full range of active layer depths to be simulated; by contrast, with a poorly resolved soil at least 50 % of the permafrost area has a maximum thaw depth at the centre of the bottom soil layer. Thus all the model modifications are seen to improve the permafrost simulations. Historical permafrost area corresponds fairly well to observations in all simulations, covering an area between 14 and 19 million km2. Simulations under two future climate scenarios show a reduced sensitivity of permafrost degradation to temperature, with the near-surface permafrost loss per degree of warming reduced from 1.5 million km2 °C-1 in the standard version of JULES to between 1.1 and 1.2 million km2 °C-1

  2. Quantifying uncertainties of permafrost carbon–climate feedbacks

    Directory of Open Access Journals (Sweden)

    E. J. Burke

    2017-06-01

    Full Text Available The land surface models JULES (Joint UK Land Environment Simulator, two versions and ORCHIDEE-MICT (Organizing Carbon and Hydrology in Dynamic Ecosystems, each with a revised representation of permafrost carbon, were coupled to the Integrated Model Of Global Effects of climatic aNomalies (IMOGEN intermediate-complexity climate and ocean carbon uptake model. IMOGEN calculates atmospheric carbon dioxide (CO2 and local monthly surface climate for a given emission scenario with the land–atmosphere CO2 flux exchange from either JULES or ORCHIDEE-MICT. These simulations include feedbacks associated with permafrost carbon changes in a warming world. Both IMOGEN–JULES and IMOGEN–ORCHIDEE-MICT were forced by historical and three alternative future-CO2-emission scenarios. Those simulations were performed for different climate sensitivities and regional climate change patterns based on 22 different Earth system models (ESMs used for CMIP3 (phase 3 of the Coupled Model Intercomparison Project, allowing us to explore climate uncertainties in the context of permafrost carbon–climate feedbacks. Three future emission scenarios consistent with three representative concentration pathways were used: RCP2.6, RCP4.5 and RCP8.5. Paired simulations with and without frozen carbon processes were required to quantify the impact of the permafrost carbon feedback on climate change. The additional warming from the permafrost carbon feedback is between 0.2 and 12 % of the change in the global mean temperature (ΔT by the year 2100 and 0.5 and 17 % of ΔT by 2300, with these ranges reflecting differences in land surface models, climate models and emissions pathway. As a percentage of ΔT, the permafrost carbon feedback has a greater impact on the low-emissions scenario (RCP2.6 than on the higher-emissions scenarios, suggesting that permafrost carbon should be taken into account when evaluating scenarios of heavy mitigation and stabilization

  3. Planeta Verne. La vuelta al mundo en ochenta libros

    OpenAIRE

    Martínez de Pisón, Eduardo

    2015-01-01

    Eduardo Martínez de Pisón se centra en la faceta geográfica de Julio Verne a través de un libro suyo titulado la “Tierra de Jules Verne. Geografía y aventura”, en donde se realiza una introducción a la obra geográfica del escritor. Para ello, el autor analiza la producción literaria de Verne buscando elementos geográficos en los pasajes de ficción y se estudia en relación a la abundante e influyente base geográfica de sus relatos. También se analiza el valor manifiestamente pedagógico de la o...

  4. The mystery of the seven spheres how homo sapiens will conquer space

    CERN Document Server

    Bignami, Giovanni F

    2015-01-01

    In this book, Giovanni Bignami, the outstanding Italian scientist and astronomer, takes the reader on a journey through the “seven spheres”, from our own planet to neighboring stars. The author offers a gripping account of the evolution of Homo Sapiens to the stage where our species is developing capabilities, in the form of new energy propulsion systems, that will enable us to conquer space. The reader will learn how we first expanded our activities to reach beyond our planet, to the Moon, and how nuclear energy, nuclear fusion, and matter–antimatter annihilation will enable us to extend our exploration. After Mars and Jupiter we shall finally reach the nearest stars, which we now know are surrounded by numerous planets, some of which are bound to be habitable. The book includes enticing descriptions of such newly discovered planets and also brings alive key historical characters in our story, such as Jules Verne and Werner von Braun.

  5. L’Asie mystérieuse : premier numéro du Bulletin du Club Verne

    Directory of Open Access Journals (Sweden)

    Alain Chiron

    2012-02-01

    Full Text Available Depuis 2007 l’Association des Amis du Roman populaire a son siège et son centre de documentation à Vignacourt près d’Amiens. Si la revue Le Rocambole qu’elle produit perdure, cette association a souhaité replacer dans des objectifs de vulgarisation l’œuvre de Jules Verne dans le contexte de production de romans populaires pour la période allant des débuts du XIXe siècle à la Grande Guerre. D’où la création du nouveau périodique le Bulletin du Club Verne. Il est nécessaire de distinguer ce der...

  6. Review and Assessment of ATV Observation Data for Events Characterization

    Science.gov (United States)

    Mazoue, Franck; Beck, James; Reynier, Philippe

    2011-02-01

    For investigating ATV re-entry, observation airborne campaigns have been carried out at the end of the mission to ISS of Jules Verne ATV. The observations of re-entry have highlighted that the in-flight scenario was quite different to the nominal one, since two explosions occurred during the flight. In this paper, the data gathered during the observations have been analysed in the perspective of the explosion analysis. The potential explosive elements present on board have been studied and the explosion products identified. To identify the possible scenario that led to the vehicle explosion the list of explosion products has been compared with the radiators put in evidence in the spectra obtained by spectroscopy during the flight. Finally, the most reliable scenario has been identified and the power available for explosion evaluated. This shows that non negligible delta V could have been produced by the explosion.

  7. Preliminary study of disc hydrodynamic polishing.

    Science.gov (United States)

    Li, Yan; Lin, Bin; Zhang, XiaoFeng; Liu, PengFei

    2016-10-01

    In this paper, a developed polishing method based on elastic emission machining and Jules Verne-a variation on fluid jet polishing-is presented. This method is named disc hydrodynamic polishing (DHDP). A computational fluid dynamics (CFD)-based model that consists of a CFD model and an erosion model is introduced to predict the surface roughness obtained by DHDP. The performance of DHDP is studied by experiments. The slurry used in the experiments comprises 95% deionized water and 5% cerium oxide particles. Fused-silica glass is chosen as the workpiece. After the experiments, an ultrasmooth surface without cracks is obtained. The simulation results principally coincide with the experimental results. The experimental results show that the actual roughness is slightly less than the prediction and smaller particles are more favorable for obtaining a better surface roughness.

  8. Airborne re-entry observation experiment SLIT: UV spectroscopy during STARDUST and ATV1 re-entry

    Science.gov (United States)

    Löhle, Stefan; Wernitz, Ricarda; Herdrich, Georg; Fertig, Markus; Röser, Hans-Peter; Ritter, Heiko

    2011-09-01

    Emission spectra during re-entry have been measured in 2006 for the STARDUST capsule and in 2008 for the ATV1 "Jules Verne" re-entry. This paper summarizes the approach to design the airborne UV spectroscopic setup and its modifications with respect to the missions. For the STARDUST mission, results of data analysis of data presented in 2008 are given while for the ATV1 observation first spectra of the main disruption are exemplary presented. The surface radiation during the STARDUST re-entry is used to estimate convective and radiative heat flux using different analytical models. A first look at the spectroscopic footprint of ATV1 shows that during the first explosive event, a severe break-up of the main ATV1 structure occurs. However, a correlation with an explosion of fuel could not be observed.

  9. Assessment of the ATV-1 Re-Entry Observation Campaign for Future Re-Entry Missions

    Science.gov (United States)

    Lips, T.; Lohle, S.; Marynowsky, T.; Rees, D.; Stenbeak-Nielsen, H. C.; Beks, M. L.; Hatton, J.

    2010-09-01

    This paper summarizes the midterm results of the currently ongoing ESA study “Assessment of the ATV-1 Reentry Observation Campaign for Future Re-entry Missions”. The primary objective of this study is to investigate the data obtained during a joint ESA/NASA airborne observation campaign of the destructive re-entry of ATV-1 Jules Verne which occurred on September 29, 2008. The presented results are focused on spectroscopic fragment characterization(material identification), frame-by-frame fragment tracking(manual and automatic) for various video recordings, 3D triangulation of the tracked fragments, and fragment propagation until complete demise or ground impact, including the actual size and location of the ATV-1 debris footprint. Fragment propagation analyses comprise also the derivation of aerodynamic fragment properties and potential delta velocities. These parameters are of high importance for the re-entry safety analysis for ATV-2 Johannes Kepler.

  10. ANITA: The European Technology Demonstrator for Trace Gas Monitoring in the International Space Station Atmosphere

    Science.gov (United States)

    Tan, Gijsbert; Mosebach, Herbert; Honne, Atle

    2005-12-01

    The accumulation of toxic or otherwise harmful trace gases in a spacecraft cabin is a very serious concern in terms of health and safety of the crew. Much progress has been made in developing techniques for monitoring the air quality on board and in near-real-time. The technique developed in Europe has reached the state of an in-flight technology demonstrator. ANITA (Analysing Interferometer for Ambient Air) is based on FTIR (Fourier Transform Infra-Red) Spectrometry. ANITA is calibrated to identify and quantify quasi online more than 30 contaminants at low ppm (part per million) or sub-ppm detection limits.ANITA is a European Space Agency (ESA) - National Aeronautics and Space Administration (NASA) cooperative programme.ANITA will be launched with Jules Verne, the maiden flight of the Automatic Transfer Vehicle (ATV) currently scheduled for June 2007.

  11. The flight experiment ANITA—a high performance air analyser for manned space cabins

    Science.gov (United States)

    Stuffler, T.; Mosebach, H.; Kampf, D.; Honne, A.; Tan, G.

    2004-08-01

    Analysing Interferometer for Ambient Air (ANITA) is a flight experiment as precursor for a permanent continuous trace gas monitoring system on the International Space Station (ISS). For over 10 years, under various ESA contracts the flight experiment was defined, designed, breadboarded and set up. For the safety of the crew, ANITA can detect and quantify quasi on-line and simultaneously 32 trace gases with ppm or sub-ppm detection limits. The self-standing measurement system is based on Fourier Transform Infrared Spectrometer (FTIR) technology. The system represents a versatile air monitor allowing for the first time the detection and monitoring of trace gas dynamics of a spacecraft atmosphere. It is envisaged to accommodate ANITA in a Destiny (US LAB) Express Rack on the ISS. The transportation to the ISS is planned with the first ATV 'Jules Verne'. The options are either the Space Shuttle or the Automated Transfer Vehicle.

  12. Long Range Validation of ATV-ISS Rendez-Vous and Docking Using EPOSx

    Science.gov (United States)

    Schreutelkamp, E.

    2008-08-01

    On April 3 at 16:40, Jules Verne, the first of a series at least 5 Automated Transfer Vehicles (ATV) docked successfully and safely at the International Space Station (ISS). This paper describes the very large test facility that was needed to perform the validation of the Rendez Vous and Docking (RVD) of this safety critical process. It describes the facility in detail as well as the Hardware and Software mechanisms needed to perform these tests at such a large scale while still meeting the high accuracy and safety requirements for the docking procedures. Furthermore it describes the environmental conditions needed to be such that the real flight hardware could be used without risk. The paper also tries to answer the question if designing such a large test facility so late into the ATV development process was a wise decision and if all that effort paid off in the end.

  13. Man and the moon—The history of lunar exploration

    Science.gov (United States)

    Mueller, George E.

    This paper delineates historical events and publications representing the human desire for exploring the Moon. Astronomers such as J. Kepler and H. Pickering were early promotors of the idea to reach out for the Moon. Many writers (Lucian, Goodwin, Cyrano de Bergerac, Jules Verne, H. G. Wells) were fascinated by the possibility of travel to the Moon. The beginning of the space age in 1957 saw early attempts to place a man-made object on the surface of the Moon, which succeeded in September 1959. Soft landers provided the first hard information on the lunar surface in the years 1966 -1968 to be followed by six manned landings in the years 1969-1972 providing a wealth of data of our neighbouring planet. Very little has happened in the years thereafter. The time has come to return to the Moon first with unmanned polar satellites to be followed by man to stay there for good.

  14. The body's tailored suit: Skin as a mechanical interface.

    Science.gov (United States)

    Tissot, Floriane S; Boulter, Etienne; Estrach, Soline; Féral, Chloé C

    2016-11-01

    Skin, by nature, is very similar to the Rouquayrol-Denayrouze suit mentioned by Jules Verne in Twenty Thousand Leagues Under the Sea: it allows "to risk (…) new physiological conditions without suffering any organic disorder". Mechanical cues, to the same extent as other environmental parameters, are such "new physiological conditions". Indeed, skin's primary function is to form a protective barrier to shield inner tissues from the external environment. This requires unique mechanical properties as well as the ability to sense mechanical cues from the environment in order to prevent or repair mechanical damages as well as to function as the primary mechanosensory interface of the whole body. Copyright © 2016 Elsevier GmbH. All rights reserved.

  15. The flight experiment ANITA--a high performance air analyser for manned space cabins.

    Science.gov (United States)

    Stuffler, T; Mosebach, H; Kampf, D; Honne, A; Tan, G

    2004-01-01

    Analysing Interferometer for Ambient Air (ANITA) is a flight experiment as precursor for a permanent continuous trace gas monitoring system on the International Space Station (ISS). For over 10 years, under various ESA contracts the flight experiment was defined, designed, breadboarded and set up. For the safety of the crew, ANITA can detect and quantify quasi on-line and simultaneously 32 trace gases with ppm or sub-ppm detection limits. The self-standing measurement system is based on Fourier Transform Infrared Spectrometer (FTIR) technology. The system represents a versatile air monitor allowing for the first time the detection and monitoring of trace gas dynamics of a spacecraft atmosphere. It is envisaged to accommodate ANITA in a Destiny (US LAB) Express Rack on the ISS. The transportation to the ISS is planned with the first ATV 'Jules Verne'. The options are either the Space Shuttle or the Automated Transfer Vehicle. c2004 Elsevier Ltd. All rights reserved.

  16. The Brick Moon

    Science.gov (United States)

    2004-01-01

    Science fiction writers, like Jules Verne in France and Edward Everett Hale in America, had discovered one of the most vital elements in the formula for space travel-a fertile imagination. The first known proposal for a marned-satellite appears in a story by Hale entitled 'The Brick Moon' published in 1899. The story involved a group of young Bostonians who planned to put an artificial satellite into polar orbit for sailors to use to determine longitude accurately and easily. They planned to send a brick satellite into orbit because the satellite would have to withstand fire very well. The Satellite's 37 inhabitants signaled the Earth in morse code by jumping up and down on the outside of the satellite.

  17. Laurent MANNONI, Marc de la FERRIÈRE, Paul DEMENY, Georges Demenÿ, pionnier du cinéma, Douai, Éd. Pagine, 1997, 192 p., ill. NB, bibl., filmographie, 195 F.

    OpenAIRE

    Braun, Marta

    2002-01-01

    Dirigé par Laurent Mannoni, responsable des collections à la Cinémathèque française et spécialiste de Demenÿ, cet ouvrage exploite de façon approfondie une foule de documents, lettres, archives, films ou photographies récemment mis à jour, sur lesquels la célébration du centenaire du cinéma a attiré l'attention. Intitulé "Demenÿ, le voleur de feu", l'essai de Mannoni forme la première et la plus importante partie du recueil. Connu pour avoir été le préparateur d'Étienne-Jules Marey, Ge...

  18. Gérer les bonnes pratiques des entreprises : Entre gestion des connaissances et veille stratégique

    OpenAIRE

    Stanel, Sorin

    2004-01-01

    Jury : Arnaud JULES, Diocèse de Paris Olivia VERGER, IMS-Entreprendre pour la Cité; Retour d'expérience sur une démarche prospective et expérimentale globale (avec le développement des dimensions organisationnelles, techniques et humaines), menée au sein de l'organisation IMS-Entreprendre pour la Cité. Ce mémoire porte sur la mise en œuvre de stratégies de veille et de gestion des connaissances dans une structure de type réseau, sujette aux avantages et aux contraintes du monde de l'entrepris...

  19. Planeta Verne. La vuelta al mundo en ochenta libros

    OpenAIRE

    Martínez de Pisón, Eduardo

    2015-01-01

    Eduardo Martínez de Pisón se centra en la faceta geográfica de Julio Verne a través de un libro suyo titulado la “Tierra de Jules Verne. Geografía y aventura”, en donde se realiza una introducción a la obra geográfica del escritor. Para ello, el autor analiza la producción literaria de Verne buscando elementos geográficos en los pasajes de ficción y se estudia en relación a la abundante e influyente base geográfica de sus relatos. También se analiza el valor manifiestamente pedagógico de la o...

  20. Préface

    Directory of Open Access Journals (Sweden)

    Christian Ménard

    2009-10-01

    Full Text Available La piraterie est un phénomène fort complexe qui remonte à la nuit des temps. Déjà 5 000 ans avant J.-C., des exactions sont mentionnées en mer Egée et Méditerranée. Jules César en sera même l’une des célèbres victimes, mais saura prendre, au moment voulu, sa revanche. Tout au long des siècles, le processus restera récurrent (Atlantique, Antilles…, trouvant son apogée dans le premier quart du XIXe siècle avec l’intervention directe de l’U.S. Navy sous la férule de Thomas Jefferson, Président ...

  1. Impacts of climate variability and extreme events on the terrestrial carbon cycle of the Amazon basin

    Science.gov (United States)

    Harper, A. B.; Cox, P.; Wiltshire, A.; Friedlingstein, P.; Jones, C. D.; Mercado, L.; Groenendijk, M.; Sitch, S.

    2013-12-01

    Several climate models predict reduced dry season rainfall in the Amazon region as a consequence of climate change. Drier dry seasons could have profound negative consequences for the forest, since soil moisture levels are already near their lower limit during this time of the year. Two recent dry season droughts (during 2005 and 2010) could provide insight into the future of the region. These droughts were associated with sea surface temperature anomalies in the tropical North Atlantic Ocean. Additionally, El Niño-related temperature anomalies in the tropical Pacific Ocean can lead to drought in the northern Amazon. In this work, we use a land surface model with updated physiology and vegetation dynamics to investigate responses of the Amazon terrestrial carbon cycle to recent droughts. JULES (the Joint UK Land-Environment Simulator) is the land surface model in the Hadley Centre Earth System Model. Several recent model developments have improved its ability to replicate seasonal cycles of land fluxes in tropical forests, such as new plant functional types, plant trait-based physiological parameters, and a multi-layer canopy with two-stream radiation and sunfleck penetration. In addition, several non-standard updates to JULES can improve the model in this region: including a representation of deeper soils and efficient roots, and parameter optimization. The soil and rooting adjustments are based on previous work with the Simple Biosphere (SiB3) model, which has been tested extensively in the Amazon. SiB3 can include a climate-derived, spatially varying predictor of forest drought resistance, which enabled it to simulate forest response to persistent soil moisture deficits during two rainfall exclusion projects in the Amazon. We ran JULES from pre-industrial to present day, forced with observed climate, atmospheric CO2, and land use. A mixture of satellite- and ground-based observations was used to validate JULES seasonal cycles of surface fluxes, phenology

  2. The Nobel Prize Highlights in Immunologic History for a Century%诺贝尔奖与免疫学的百年渊源

    Institute of Scientific and Technical Information of China (English)

    刘伯宁

    2012-01-01

    2011 Nobel Prize in physiology or medicine was shared a-mong Ralph Steinman, Jules Hoffman and Bruce beutler, who dis covered biological function of Dendritic Cells and Toll like receptor respectively. Since 1901 the first-ever Nobel Prize was award to Emil von Behring for the funding of antitoxin, overall 17 Nobel pri zes in physiology and medicine were given for achievements in im munologic fields. In a historical perspective, the Nobel laureates have witnessed the whole development course of immunology as a discipline. After originated from bacteriology, immunology has un dergone major shift from immunochemistry to immunobiology, and become an important frontier discipline of the life sciences eventu ally. The review summarizes all immunologic funding awarded to Nobel Prize in physiology or medicine retrospective, and discusses the contribution of those achievements to immunologic theory de velopment and clinic medicine.

  3. Publications on Peripheral Nerve Injuries during World War I: A Dramatic Increase in Knowledge.

    Science.gov (United States)

    Koehler, Peter J

    2016-01-01

    Publications from French (Jules Tinel and Chiriachitza Athanassio-Bénisty), English (James Purves-Stewart, Arthur Henry Evans and Hartley Sidney Carter), German (Otfrid Foerster and Hermann Oppenheim) and American (Charles Harrison Frazier and Byron Stookey) physicians from both sides of the front during World War I (WWI) contributed to a dramatic increase in knowledge about peripheral nerve injuries. Silas Weir Mitchell's original experience with respect to these injuries, and particularly causalgia, during the American Civil War was further expanded in Europe during WWI. Following the translation of one of his books, he was referred to mainly by French physicians. During WWI, several French books were in turn translated into English, which influenced American physicians, as was observed in the case of Byron Stookey. The establishment of neurological centres played an important role in the concentration of experience and knowledge. Several eponyms originated during this period (including the Hoffmann-Tinel sign and the Froment sign). Electrodiagnostic tools were increasingly used.

  4. The Brick Moon

    Science.gov (United States)

    2004-01-01

    Science fiction writers, like Jules Verne in France and Edward Everett Hale in America, had discovered one of the most vital elements in the formula for space travel-a fertile imagination. The first known proposal for a marned-satellite appears in a story by Hale entitled 'The Brick Moon' published in 1899. The story involved a group of young Bostonians who planned to put an artificial satellite into polar orbit for sailors to use to determine longitude accurately and easily. They planned to send a brick satellite into orbit because the satellite would have to withstand fire very well. The Satellite's 37 inhabitants signaled the Earth in morse code by jumping up and down on the outside of the satellite.

  5. Competing roles of rising CO2 and climate change in the contemporary European carbon balance

    Directory of Open Access Journals (Sweden)

    J. K. Hughes

    2008-01-01

    Full Text Available Natural ecosystems respond to, and may affect climate change through uptake and storage of atmospheric CO2. Here we use the land-surface and carbon cycle model JULES to simulate the contemporary European carbon balance and its sensitivity to rising CO2 and changes in climate. We find that the impact of climate change is to decrease the ability of Europe to store carbon by 97 TgC yr−1. In contrast, the effect of rising atmospheric CO2 has been to stimulate increased uptake and storage. The CO2 effect is currently dominant leading to a net increase of 114 TgC yr−1. Our simulations do not at present include other important factors such as land use and management, the effects of forest age classes and nitrogen deposition. Understanding this balance and its implications for mitigation policies is becoming increasingly important.

  6. Georges Perec et le deuil de l’achèvement

    Directory of Open Access Journals (Sweden)

    Daniele Carluccio

    2014-12-01

    What is modern reading? Walter Benjamin defines the modern man, and thus the modern reader, as a “traumatophilic type”. Jules de Gaultier, the theoretician of bovarism, compares Mrs Bovary, the famous Flaubertian reading hero, to an artist constrained to incompletion, who fails to bring the ideal she finds in books to life. In this article, I explore the case of Georges Perec as reader of Raymond Roussel in an essay entitled Roussel and Venice. Outline of a Melancholic Geography. Secondly, I focus on Perec as both author and reader of W, an incomplete fiction included in an autobiographical context which reveals its traumatic origin. I attempt to show that the work of Perec is for a reader who is similar to him: a modern, melancholic reader who mourns for completion.

  7. On multi-level thinking and scientific understanding

    Science.gov (United States)

    McIntyre, Michael Edgeworth

    2017-10-01

    Professor Duzheng YE's name has been familiar to me ever since my postdoctoral years at MIT with Professors Jule CHARNEY and Norman PHILLIPS, back in the late 1960s. I had the enormous pleasure of meeting Professor YE personally in 1992 in Beijing. His concern to promote the very best science and to use it well, and his thinking on multi-level orderly human activities, reminds me not only of the communication skills we need as scientists but also of the multi-level nature of science itself. Here I want to say something (a) about what science is; (b) about why multi-level thinking—and taking more than one viewpoint—is so important for scientific as well as for other forms of understanding; and (c) about what is meant, at a deep level, by "scientific understanding" and trying to communicate it, not only with lay persons but also across professional disciplines. I hope that Professor YE would approve.

  8. Blood pressure measurement: lessons learned from our ancestors.

    Science.gov (United States)

    Karamanou, Marianna; Papaioannou, Theodore G; Tsoucalas, Gregory; Tousoulis, Dimitris; Stefanadis, Christodoulos; Androutsos, George

    2015-01-01

    The profound observations of William Harvey (1578-1657), in blood circulation and the progress of physical science laid the foundation for the development of the Iatrophysical School that contributed to the evolution of clinical sphygmomanometry. The pioneer work of Reverend Stephen Hales (1677-1761) demonstrated the dynamics of the vascular system. One century later the French physician Jean-Léonard-Marie Poiseuille (1797-1867) invented a U-tube mercury manometer and in 1860 the physiologist Etienne- Jules Marey (1830-1904) devised the first portable sphygmograph for recording the pulse wave. The non-invasive techniques of blood pressure measurement were completed by Scipione Riva-Rocci (1896-1937) sphygmomanometer and the description of "Korotkov sounds" by the Russian surgeon Nikolai- Sergeyevich Korotkov (1874-1920).

  9. Thaïs ou la sublimation d’Eros

    Directory of Open Access Journals (Sweden)

    Léonard Rosmarin

    2005-04-01

    Full Text Available Avec son mélange singulier de sensualité et d’austérité, de religion et de paganisme, d’érotisme et de chasteté, le roman d’Anatole France, Thaïs, reflète l’ambiance fin de siècle dans laquelle l’auteur l’écrivit, à savoir, 1890. Le compositeur Jules Massenet et son librettiste, Louis Gallet furent fidèles au texte à leur façon quand ils en montèrent la version opératique du même nom quatre ans plus tard, mais à leur façon seulement, le théâtre lyrique ayant ses exigences propres impossibles à contourner.

  10. Restoration of an old telescope: a pedagogic opportunity

    Science.gov (United States)

    Gall Christophe, Le

    2016-04-01

    The "Lycée Jules Haag" High School is a former clockwork learning school. It has a telescope, built in the 1930's, which was used to calibrate time for watches. Nowadays, this telescope is no longer of any practical use, and has been classified for its historical interest. Thanks to the financial help of local companies, a new pedagogic project has started inside our school. This astronomical device is going to be repaired, and many teachers and classes will be involved. This will create opportunities during and after the restoration. Our High School will have practical classes that may work around the motorisation of the telescope and creating a new eyepiece. When the telescope is operational, we can use this device for physics and optics classes, and organise an astronomical club to do some day and night observations.

  11. Distributed hydrological models to quantify ecosystem services and inform land use decisions in Europe

    Science.gov (United States)

    Wilebore, Beccy; Willis, Kathy

    2016-04-01

    Landcover conversion is one of the largest anthropogenic threats to ecological services globally; in the EU around 1500 ha of biodiverse land are lost every day to changes in infrastructure and urbanisation. This land conversion directly affects key ecosystem services that support natural infrastructure, including water flow regulation and the mitigation of flood risks. We assess the sensitivity of runoff production to landcover in the UK at a high spatial resolution, using a distributed hydrologic model in the regional land-surface model JULES (Joint UK Land Environment Simulator). This work, as part of the wider initiative 'NaturEtrade', will create a novel suite of easy-to-use tools and mechanisms to allow EU landowners to quickly map and assess the value of their land in providing key ecosystem services.

  12. Les Rȇves de la Fée Verte : L’absinthe dans les romans de la deuxième moitié du XIXe siècle (Dreams of The Green Fairy: Absinthe in The Novels of The Second Half of The 19th Century

    Directory of Open Access Journals (Sweden)

    Eva Voldřichová Beránková

    2016-09-01

    Full Text Available Fabricated from the end of the 18th century, popularized after 1830 by French soldiers returning from Algeria, crowned the green fairy of the Parisian boulevards around 1860, the absinthe dominates the fin-de-siècle imagination as the principal means of transport “anywhere out of the world”. This article resumes the paradoxical mythology of this beverage that appears in French novels in the second half of the 19th century. Octave Féré, Jules Cauvain and the Goncourt brothers give a warning against its pernicious power, while Emile Zola’s attitude to the absinthe is more ambiguous. The magical potential of the green fairy seems to be tempting the father of naturalism who mixes science and mythology, the probable and the grotesque, the strict laws of heredity and the supernatural lightness of a blue flame coming from the “spontaneous combustion”.

  13. La Fortification de Troyes en Champagne. Un grand chantier urbain Fin XVe–première moitié du XVIe siècle

    Directory of Open Access Journals (Sweden)

    Brice Collet

    2011-05-01

    Full Text Available Composition du JuryMonsieur Patrick Boucheron, maître de conférence à l’Université de Paris I,Madame Odette Chapelot, maître de conférence à l’ÉHESS,Monsieur Jean Chapelot, directeur de recherche au CNRS (directeur de la thèse,Monsieur Nicolas Faucherre, professeur à l’Université de Nantes,Monsieur Etienne Hamon, professeur à l’Université de Picardie–Jules Verne,Monsieur Pierre Monnet, directeur d’études à l’ÉHESS.Thèse soutenue le 16 décembre 2010RésuméIl ne reste actuellement plus rien ou ...

  14. A clinical study of annular cyclitis

    Directory of Open Access Journals (Sweden)

    Marilita Michael Moschos

    2009-02-01

    Full Text Available Marilita Michael Moschos1, Yan Guex-Crosier2, Ioannis Margetis1, Leonidas Zografos21Department of Ophthalmology, University of Athens, Greece; 2Jules Gonin Eye Hospital, University of Lausanne, SwitzerlandPurpose: To investigate six cases of annular cyclitis.Methods: All patients with impairment of visual acuity underwent complete ophthalmologic examination, color fundus photography, laboratory tests and fluorescein angiography. Indocyanine green (ICG angiography and B-scan ultrasonography were also performed in three cases in order to diagnose the disease.Results: All patients presented a unilateral or bilateral granulomatous uveitis, associated with inflammatory annular cyclitis. They had a shallow anterior chamber, a mildly elevated intraocular pressure (under 25 mm Hg and an annular serous retinal detachment. A resolution was observed after specific therapy associated with systemic prednisolone therapy and antiglaucomatous drops.Conclusion: This is the first description of an observational study of six patients with inflammatory annular cyclitis.Keywords: cyclitis, uveitis, malignant glaucoma

  15. Recueil de documents

    OpenAIRE

    Dedieu, Jean-Pierre

    2013-01-01

    Document I. Philippe II en Jules César La campagne de Saint-Quentin vue par un historiographe du roi (1557) Le polygraphe Ginés de Sepúlveda (1490-1573) est célèbre par sa controverse avec Las Casas sur la légitimité de la conquête des Indes. Il est moins connu comme auteur d’une chronique latine du règne de Charles V, à laquelle il donna pour suite une chronique des six premières années du règne de Philippe II, sous le titre de De rebus gestis Philippi II. Son manuscrit resta inédit jusqu’à ...

  16. New evaluation of photon production for JEFF-3

    Science.gov (United States)

    Ravaux, S.; Bernard, D.; Santamarina, A.

    2013-03-01

    In this work, new gamma production evaluations are proposed for JEFF-3 for crucial nuclei for power reactors and Jules Horowitz Reactor: Fe, Ag, In, Cd and Gd. We specifically work on two nuclear reactions: the inelastic scattering and the radiative capture. We performed gamma production multiplicities, angular distributions and energy spectrum for incident neutron energies between 10-11 and 20 MeV by simulating the whole intranuclear gamma cascade. For this simulation, the discrete part of the nuclei level schemes came from the RIPL2.0 library and the latest EGAF measurements carried out at Budapest facility. The EGAF measurements are available in the adopted IAEA library. The continuum level scheme part has been estimated with a level density model: the Gilbert-Cameron model and a strength function model: the Generalized Lorentzian model. Then, the gamma cascade has been simulated using TALYS which is a nuclear reaction modeling code.

  17. The Dead Mother, the Uncanny, and the Holy Ghost

    Directory of Open Access Journals (Sweden)

    Gal Ventura

    2015-01-01

    Full Text Available Recurrent portrayals of dead mothers frequently appeared in French art from 1800 to 1850. This essay focuses on one of the latest manifestations of this image, namely, the French Realist Jules Breton's (1827-1906 painting The Hunger of 1850, in order to examine the psycho-historical elements associated with the mother's death. Through an analysis of the "Uncanny" as formulated by both Ernst Jentsch and Sigmund Freud, we will address the undissolvable link between the structuralization of "homeliness" in the late eighteenth century and the dread it evoked in the early nineteenth century, as two sides of the same coin. We will simultaneously consider the inherent conflictuality embodied by the dead mother according to the French psychoanalyst André Green, who dealt with the experience of "nothingness" that characterizes children of mothers-who-refuse-to-die.

  18. Dalla pagina bianca a quella pentagrammata: quando Ravel si appropriò degli animali di Renard

    Directory of Open Access Journals (Sweden)

    Liana Püschel

    2012-12-01

    Full Text Available In 1907 Maurice Ravel decided to convert into mélodies (typical French genre of songs five prose works taken from the collection Les Histoires Naturelles written by Jules Renard; the musician’s aim was to say with music what the writer said with words, but from the work emerges a personal interpretation of the texts. This paper studies the musical adaptation of the stories through the analysis of the score and of the cultural context. The little songs are a distillation of irony and refinement and, because of their apparently banal and prosaic content, they arose scandal at their first performance. Ravel’s animals do not display shallowness in order to outrage the audience, they aim to introduce a new idea of music indifferent to rhetoric and to inauthentic aspirations.

  19. Calculation to experiment comparison of SPND signals in various nuclear reactor environments

    Energy Technology Data Exchange (ETDEWEB)

    Barbot, Loic; Radulovic, Vladimir; Fourmentel, Damien [CEA, DEN, DER, Instrumentation, Sensors and Dosimetry Laboratory, Cadarache, F-13108 St-Paul-Lez-Durance, (France); Snoj, Luka [Jozef Stefan Institute, Jamova cesta 39, SI-1000 Ljubljana, (Slovenia); Tarchalski, Mikolaj [National Centre for Nuclear Research, ulica Andrzeja Soltana 7, 05-400 Otwock (Swierk), (Poland); Dewynter-Marty, Veronique [CEA, DEN, DANS, DRSN, SIREN, LESCI, Saclay, F-91191 Gif sur Yvette, (France); Malouch, Fadhel [CEA, DEN, DANS, DM2S, SERMA, Saclay, F-91191 Gif sur Yvette, (France)

    2015-07-01

    In the perspective of irradiation experiments in the future Jules Horowitz Reactor (JHR), the Instrumentation Sensors and Dosimetry Laboratory of CEA Cadarache (France) is developing a numerical tool for SPND design, simulation and operation. In the frame of the SPND numerical tool qualification, dedicated experiments have been performed both in the Slovenian TRIGA Mark II reactor (JSI) and very recently in the French CEA Saclay OSIRIS reactor, as well as a test of two detectors in the core of the Polish MARIA reactor (NCBJ). A full description of experimental set-ups and neutron-gamma calculations schemes are provided in the first part of the paper. Calculation to experiment comparison of the various SPNDs in the different reactors is thoroughly described and discussed in the second part. Presented comparisons show promising final results. (authors)

  20. The first international leprosy conference, Berlin, 1897: the politics of segregation.

    Science.gov (United States)

    Pandya, S S

    2004-01-01

    The present paper examines the first attempts to internationalise the problem of leprosy, a subject hitherto overlooked by historians of imperialism and disease. The last decade of the nineteenth century saw many in the civilised countries of the imperialist West gripped by a paranoia about an invasion of leprosy via germ-laden immigrants and returning expatriates who had acquired the infection in leprosy endemic colonial possessions. Such alarmists clamoured for the adoption of vigorous leper segregation policies in such colonies. But the contagiousness of leprosy did not go unquestioned by other westerners. The convocation in Berlin of the first international meeting on leprosy revealed the interplay of differing and sometimes incompatible views about the containment of leprosy by segregation. The roles of officials from several countries, as well as the roles of five protagonists (Albert Ashmead, Jules Goldschmidt, Edvard Ehlers. Armauer Hansen, and Phineas Abraham) in the shaping of the Berlin Conference are here examined.

  1. Adaptar es respetar

    Directory of Open Access Journals (Sweden)

    Juan Orellana Gutiérrez de Terán

    2014-02-01

    Full Text Available La profesora Lozano parece ofrecernos una versión de su investigación doctoral, que consta de dos partes muy fáciles de deslindar. En una primera nos ofrece un corpus teórico relativo al lenguaje del cine, al lenguaje literario, y a la adaptación del segundo al primero. En la segunda parte, se centra en un análisis práctico de la adaptación de ‘Tener o no tener’, dirigida por Howard Hawks, con un guión de William Faulkner y Jules Furthman basado en la novela de Hemingway. 

  2. Reflexiones sobre "las Diabólicas"

    Directory of Open Access Journals (Sweden)

    Manuela SAN MIGUEL

    2009-12-01

    Full Text Available Coincide la aparición en librería de una nueva edición de «Efigies» de Gómez de la Serna, con el centenario de uno de los cinco «malditos» biografiados, con la sensibilidad y penetración que le caracteriza, por el autor de las «Greguerías». Ello pone doblemente de actualidad la figura un tanto esperpéntica, de Jules Amedée Barbey d'Aurevilly, el «Condestable de las Letras», ese curioso escritor de quien dice Ramón «que nadie acierta a comprender a qué estética pertenecen sus obras».

  3. Testicular germ cell tumor: Short and long-term side effects of treatment among survivors.

    Science.gov (United States)

    Gil, Thierry; Sideris, Spyridon; Aoun, Fouad; van Velthoven, Roland; Sirtaine, Nicolas; Paesmans, Marianne; Ameye, Lieveke; Awada, Ahmad; Devriendt, Daniel; Peltier, Alexandre

    2016-09-01

    Long-term prognosis of germ cell tumor (GCT) types is excellent, however, treatment is associated with non-negligible complication rates and a negative impact on quality of life. The present study described treatment results in terms of survival, both short and long-term toxicity, and paternity rates in a cohort of patients treated at Jules Bordet Institute, University ULB of Brussels (Brussels, Belgium). The present study analyzed the data of a cohort of patients with GCT types. Pre-operative patient and tumor characteristics were described. Performance status, pulmonary function tests and renal clearance prior to chemotherapy were noted. Chemotherapeutic regimens and their associated toxicities were analyzed. The duration to event-free, cancer-specific and overall survivals were estimated using Kaplan-Meier curves. A total of 115 patients (median age, 31-years-old) were treated for a GCT at Jules Bordet Institute. At a median follow-up of 6-years, 11 (10%) patients had relapsed and 2 (2%) developed a second malignant neoplasm. At the final follow-up, 97 (89%) and 6 (5.5%) patients exhibited complete and partial remission, respectively. A total of 6% of patients exhibited a progressive disease. In terms of short-term toxicity, 11% of patients presented with febrile neutropenia. The 10-year overall survival rate and relapse-free survival rate were 93.4 and 89.8%, respectively. The paternity rate post-treatment was 27%. Testicular GCT survivors suffered from short- and long-term treatment-associated side effects on both a physical and psychological level. A long-term close follow-up is necessary in order to assist the patient with these treatment-induced complications.

  4. Human Flight Batteries NI-CD/LI-MNO2

    Science.gov (United States)

    Lagattu, Benoit; Granger, Jean-Francois

    2011-10-01

    The ATV, as European space tug for the International Space Station, can be truly considered as a manned platform, when it comes to safety requirements. On board batteries have to comply with stringent requirements and insure a fully safe operation all along the mission. Though,ATV batteries manufacturer designed developed and supplied all onboard primary and rechargeable batteries required for the ATV Jules Verne. The batteries for future ATV missions will be supplied until 2015 within the framework of a long-term contract with the ATV manufacturer. Use of primary lithium batteries (Li-MnO2) for collision avoidance and de-orbitation offer a particular advantage for spacecraft as their high specific energy helps reducing the overall weight. They also comply with safety qualifications for manned flight missions. 100 minutes after lift-off, the ATV became a fully automated spacecraft navigating towards the ISS. During this phase, its main power is derived from four large solar wings with backup provided by four nickel- cadmium (Ni-Cd) batteries. Once docked, the Ni-Cd batteries will continue to provide power for the ATV for about 30 minutes (the approximate duration solar panels are eclipsed by the Earth's shadow) each 90-minute orbit. Ni-Cd batteries offer a particularly robust and reliable solution for this application, with a spaceflight heritage that goes back over 40 years. This paper outlines how Ni-Cd and Li-MnO2 batteries performed during flight operations of Jules Verne spacecraft and how they met performances predictions through lift off, orbital flight and atmosphere reentry.

  5. Post-Flight Analysis of Dynamic Data Acquired During the ATV-2 Johannes Kepler Launch

    Science.gov (United States)

    Meitzner, R.; Abdoly, K.; Newerla, A.

    2012-07-01

    An in-flight data acquisition system called TeleMesure Autonome (TMA) has been implemented on ATV-1 Jules Verne (launched in March 2008) and ATV-2 Johannes Kepler (launched in February 2011). The TMA served the main objective to measure dynamic responses on the ATV spacecraft for comparison with coupled load analysis predictions and to verify that the ATV mechanical flight environment has been sufficiently covered by the respective ATV design specifications. The acquired flight data included low frequency sinusoidal, random vibration and shock measurements. Whereas the TMA on ATV-1 Jules Verne failed to properly work after 17 seconds after liftoff the improved TMA on ATV-2 Johannes Kepler performed its tasks successfully for all flight phases. The flight data have been subsequently evaluated by the ATV prime contractor Astrium. As first step of the performed analyses a correction of the acquired data was necessary to remove any artificial content (spikes, mean truncation, offset correction) followed by a visual inspection of the corrected data to ensure data quality. Then standard post processing methods were applied to the data consisting of generating equivalent sinusoidal responses and transfer functions for the low frequency data, power spectral densities for the random data and shock responses for the high frequency shock data. Although it was noted that the quality of the data was limited by the available transmission bandwidth and the amplitude resolution of the data acquisition system the implementation of the TMA on ATV-2 Johannes Kepler has nevertheless turned out successful and valuable data have been acquired for all relevant flight phases.

  6. 艾儒略中文天主教著作版本综考

    Institute of Scientific and Technical Information of China (English)

    谢辉

    2016-01-01

    艾儒略为明末来华之著名耶稣会士,中文著作达20余种,其中大部分为天主教类著作。这些著作按内容可分为五类,其主要版本多收藏于梵蒂冈图书馆、耶稣会罗马档案馆、法国国家图书馆、中国国家图书馆、台湾辅仁大学图书馆等处。通过对以上机构藏本的调查,结合中外目录的著录,可以对艾儒略所著16种天主教著作的版本作出全面考察,明确版本关系,揭示异同优劣。%Jules Aleni is a famous Jesuit who came to China in late Ming Dynasty. He wrote more than 20 kinds of written works in Chinese, most of which are related to Catholicism. Those works can be divided into five types based on their contents. The ma⁃jor versions are mainly collected in Biblioteca Apostolica Vaticana, Roman Jesuitic Archives, Bibliothèque nationale de France, National Library of China and Fujen University Library. According to examining those collections mentioned above and combin⁃ing catalogue records both in China and other foreign countries, the version system of 16 kinds of Catholic works written by Jules Aleni can be overall investigated, the relationship among all versions can be clarified, and their similarities&differences, advan⁃tages&disadvantages can be also revealed.

  7. [Louis Maurice Champagne and the "Ecole dentaire française"].

    Science.gov (United States)

    Rousseau, Claude

    2002-01-01

    The Royal Edict of Louis XIV had created a new category of practitioners, "The Teeth Experts", and at the dawn of the second half of the 19th century, France had no dental school nor specific legislation. The situation worsened when many American dentists settled in France. Thus the creating of the "Ecole dentaire de Paris" in 1880 constituted a significant event which was followed by the opening of the "Ecole Dentaire de France" in 1884 and of the "Ecole Dentaire Française" in 1896. Louis Maurice Champagne will be its director from 1926. At the St Ouen Jules Vallés Market, we fortuitously discovered a framed document containing three photographs of Louis Maurice Champagne's surgery located, 3 Place de la Madeleine in Paris. Thanks to his son and through various documents, we could trace the exceptional professional carrier of this practitioner who eventually bought the "Ecole Dentaire Française" from Dr Louis-Jules Rousseau. Then, we discuss the legal frame work of the 1892 law created the "Chirurgien-dentiste" diploma and we describe the scientific and practical teaching for the "Ecole dentaire française". The operating layout of the clinical rooms is presented by opposing the ergonomic aspect of the demonstration surgery of the director and the two large operative dentistry rooms used for students. We conclude by emphasizing Louis Maurice Champagne's determination to overcome adversity which was peculiar to him as a young orphan immigrant without resources. To solve the problem of the "Chirurgien Dentiste" statute considered by its promoters as a stage of transition towards fuller reforms, we present various projects like from Dr Hulin's. This practitioner presided the Dental Section of the Medical Council Order before being voted in the first President of the "Chirurgien Dentiste" National Council Order in 1945. In 1942 he was the first to advocate a legislation based on the independence of the dental profession, still in force nowadays.

  8. Coupled C, N and P controls on photosynthesis, primary production and decomposition across a land use intensification gradient and implications for land atmosphere C exchange

    Science.gov (United States)

    Reinsch, Sabine; Glanville, Helen; Smart, Simon; Jones, Davey; Mercado, Lina; Blanes-Alberola, Mamen; Cosby, Jack; Emmett, Bridget

    2016-04-01

    The coupling of C, N and P cycles has rarely been studied through the air- land-water continuum. This is essential if we are to enhance land-atmosphere models to account for N and P limitations. It is also important for developing integrated catchment management solutions to deliver improved water quality combined with a wide range of other ecosystem functions and services. We present results from a project which is part of the interdisciplinary pan-UK NERC Macronutrient Cycles Programme (macronutrient-cycles.ouce.ox.ac.uk/). Our aim is to quantify how coupled C, N & P cycles change across a land use intensification gradient from arable to grass, woodland and bog ecosystems and identify the implications for land-atmosphere C exchange. We focus on three key processes; photosynthesis, annual net primary productivity and decomposition and explore their consequences for biodiversity. Other aspects of the project track delivery to, and transformations within, the freshwater and coastal systems. When we explore relationships between C, N and P, results indicate all habitat types fall on a single land use intensification gradient. Stoichiometry suggests plant productivity is primarily N limited. P limitation occurs rarely but at all levels of intensification. Soil priming shows our soils are primarily C limited and, surprisingly, soil acidity provides one of the most powerful single predictors of processes and ecosystem services perhaps as it is a good integrator of many soil properties. Incorporating this knowledge into the UK land-atmosphere model JULES will improve aNPP projections. These are then being used as inputs into a plant species model called MULTIMOVE to enable future scenarios of climate change, land use and air pollution on habitat suitability for > 1400 plant species to be explored. The enhanced Jules model will ensure both N and P limitations on C fluxes from above and below-ground are incorporated into future UK scenario applications.

  9. Fine-needle aspiration biopsy in the management of choroidal melanoma.

    Science.gov (United States)

    McCannel, Tara A

    2013-05-01

    Fine-needle aspiration biopsy of choroidal melanoma offers an opportunity to determine the prognosis for metastasis and provide tissue resources for further study to develop molecular-based targeted therapies. Patients increasingly desire as much information as possible about their cancer so that they may plan their lives and investigate new treatments. Physicians who treat choroidal melanoma must become skilled in the technique so that even the smallest tumors, in patients who might benefit most from early treatment, may be safely biopsied. Individualized molecular therapies of the future will be predicated on the results of a patient's fine-needle biopsy. Fine-needle aspiration biopsy for metastatic prognostication was first performed in North America at the Jules Stein Eye Institute, the University of California, Los Angeles in 2004. Subsequent reports from the major ophthalmic oncology centers have since evaluated several platforms for prognostication using mainly DNA-based approaches. Monosomy 3 of the primary tumor is the cytogenetic abnormality most strongly associated with the development of metastasis. The longest clinical follow-up of a cohort of patients at the Jules Stein Eye Institute who underwent biopsy for prognostication reported in 2012 revealed no increase in ocular morbidity or metastatic risk. Fine-needle aspiration biopsy for prognostication in choroidal melanoma is the current standard of care because of new molecular knowledge and a more patient-centered approach to healthcare. Future targeted molecular therapies and metastatic surveillance in patients with choroidal melanoma may be directed by the results of fine-needle aspiration biopsy of the primary tumor.

  10. On the relative role of fire and rainfall in determining vegetation patterns in tropical savannas: a simulation study

    Science.gov (United States)

    Spessa, Allan; Fisher, Rosie

    2010-05-01

    LPJ-GUESS vegetation model. Recently, SPIFTIRE has been coupled to the Ecosystem Demography (ED) model, which simulates global vegetation dynamics as part of the new land surface scheme JULES (Joint UK Environment Simulator) within the QUEST Earth System Model (http://www.quest-esm.ac.uk/). This study forms part of on-going work to further improve and test the ability of JULES to accurately simulate the terrestrial carbon cycle and land-atmosphere exchanges under different climates. Using the JULES (ED-SPITFIRE) model driven by observed climate (1901-2002), and focusing on large-scale rainfall gradients in the tropical savannas of west Africa, the Northern Territory (Australia) and central-southern Brazil, this study assesses: i) simulated versus observed vegetation dynamics and distributions, and ii) the relative importance of fire versus rainfall in determining vegetation patterns. A sensitivity analysis approach was used.

  11. Mitigation potential of horizontal ground coupled heat pumps for current and future climatic conditions: UK environmental modelling and monitoring studies

    Science.gov (United States)

    García González, Raquel; Verhoef, Anne; Vidale, Pier Luigi; Gan, Guohui; Wu, Yupeng; Hughes, Andrew; Mansour, Majdi; Blyth, Eleanor; Finch, Jon; Main, Bruce

    2010-05-01

    model predictions of soil moisture content and soil temperature with measurements at different GCHP locations over the UK. The combined effect of environment dynamics and horizontal GCHP technical properties on long-term GCHP performance will be assessed using a detailed land surface model (JULES: Joint UK Land Environment Simulator, Meteorological Office, UK) with additional equations embedded describing the interaction between GCHP heat exchangers and the surrounding soil. However, a number of key soil physical processes are currently not incorporated in JULES, such as groundwater flow, which, especially in lowland areas, can have an important effect on the heat flow between soil and HE. Furthermore, the interaction between HE and soil may also cause soil vapour and moisture fluxes. These will affect soil thermal conductivity and hence heat flow between the HE and the surrounding soil, which will in turn influence system performance. The project will address these issues. We propose to drive an improved version of JULES (with equations to simulate GCHP exchange embedded), with long-term gridded (1 km) atmospheric, soil and vegetation data (reflecting current and future environmental conditions) to reliably assess the mitigation potential of GCHPs over the entire domain of the UK, where uptake of GCHPs has been low traditionally. In this way we can identify areas that are most suitable for the installation of GCHPs. Only then recommendations can be made to local and regional governments, for example, on how to improve the mitigation potential in less suitable areas by adjusting GCHP configurations or design.

  12. Ulceration of the oral mucosa following direct contact with ferrous sulfate in elderly patients: a case report and a review of the French National Pharmacovigilance Database

    Directory of Open Access Journals (Sweden)

    Liabeuf S

    2014-04-01

    Full Text Available Sophie Liabeuf,1–3 Valérie Gras,1 Julien Moragny,1 Marie-Laure Laroche,4 Michel Andrejak1,3On behalf of the French National Network of Pharmacovigilance Centers1Regional Pharmacovigilance Center, Division of Clinical Pharmacology, Amiens University Medical Center and Jules Verne University of Picardy, Amiens, France; 2Clinical Research Centre, Clinical Pharmacology Division, Amiens University Medical Center and the Jules Verne University of Picardy, Amiens, France; 3INSERM U1088, Amiens, France; 4Regional Pharmacovigilance Center, Department of Pharmacology, Toxicology and Pharmacovigilance, Limoges University Medical Center, Limoges, FranceObjective: To report a series of cases of ulceration of the oral mucosa linked to direct contact with ferrous sulfate in elderly patients.Case summary: The first case report concerns the occurrence of widespread oral ulceration in an 87-year-old woman with Alzheimer’s disease. The ulceration extended from the side of the tongue to the floor of the mouth. No clear explanation was found and various local treatments were ineffective. Once it was realized that the ferrous sulfate tablets (given as an iron supplement were crushed prior to administration (due to the patient’s deglutition disorder, withdrawal of this treatment led to rapid resolution of the ulceration. Nine other cases of oral ulcerations associated with ferrous sulfate were identified in the French National Pharmacovigilance Database. All but one of the patients were over 80 years of age and the youngest patient (a 54-year-old had dysphagia associated with facial paralysis.Discussion: Only two other reports of oral ulceration due to ferrous sulfate have been published to date. Mucosal toxicity of ferrous sulfate (which is probably related to oxidative stress has previously been reported for the hypopharynx, the esophageal lumen, and (after inhalation of a tablet the tracheobronchial tree.Conclusion: The mucosal toxicity of ferrous

  13. Interactive Geophysical Mapping on the Web

    Science.gov (United States)

    Meertens, C.; Hamburger, M.; Estey, L.; Weingroff, M.; Deardorff, R.; Holt, W.

    2002-12-01

    We have developed a set of interactive, web-based map utilities that make geophysical results accessible to a large number and variety of users. These tools provide access to pre-determined map regions via a simple Html/JavaScript interface or to user-selectable areas using a Java interface to a Generic Mapping Tools (GMT) engine. Users can access a variety of maps, satellite images, and geophysical data at a range of spatial scales for the earth and other planets of the solar system. Developed initially by UNAVCO for study of global-scale geodynamic processes, users can choose from a variety of base maps (satellite mosaics, global topography, geoid, sea-floor age, strain rate and seismic hazard maps, and others) and can then add a number of geographic and geophysical overlays for example coastlines, political boundaries, rivers and lakes, NEIC earthquake and volcano locations, stress axes, and observed and model plate motion and deformation velocity vectors representing a compilation of 2933 geodetic measurements from around the world. The software design is flexible allowing for construction of special editions for different target audiences. Custom maps been implemented for UNAVCO as the "Jules Verne Voyager" and "Voyager Junior", for the International Lithosphere Project's "Global Strain Rate Map", and for EarthScope Education and Outreach as "EarthScope Voyager Jr.". For the later, a number of EarthScope-specific features have been added, including locations of proposed USArray (seismic), Plate Boundary Observatory (geodetic), and San Andreas Fault Observatory at Depth sites plus detailed maps and geographically referenced examples of EarthScope-related scientific investigations. In addition, we are developing a website that incorporates background materials and curricular activities that encourage users to explore Earth processes. A cluster of map processing computers and nearly a terabyte of disk storage has been assembled to power the generation of

  14. L'aile dite « des prélats » au château de Grignan (Drôme 1684-1689

    Directory of Open Access Journals (Sweden)

    Christian Trézin

    2012-04-01

    Full Text Available La construction de l'aile « des prélats » au château de Grignan de 1684 à 1689 correspond à la requalification d'un secteur composite constitué du XIIe au XVIIe siècle. Commanditée sans intervention d'architecte par l'évêque de Carcassonne et l'archevêque d'Arles, frères du comte de Grignan, elle est bâtie en deux chantiers successifs selon des partis distincts dont l'harmonisation laborieuse est restée inachevée. Si le bâtiment de Carcassonne reflète initialement le savoir traditionnel de l'entrepreneur Florent Loiseleur, celui d'Arles est imprégné des œuvres récentes de l'agence de Jules Hardouin-Mansart dont le maçon Jacque Jaquet dit Beaufleury a probablement été tenu de s'inspirer. Ce chantier est un exemple du mode d'action des architectes amateurs dans le milieu conservateur de la noblesse provençale.The "prelates" wing of the castle of Grignan was built from 1684 to 1689. It was supposed to be a requalification and a renewal of a heterogeneous area erected between 12th to 17th century. Sponsored by the bishop of Carcassonne and the archbishop of Arles, brothers of the count of Grignan, no architect was involved in its design. It was built in two successive phases reflecting distinct conceptions and accordingly its architctural harmonization was made difficult and remained unfulfilled. If the Carcassonne building reflects the traditional savoir faire of the building contractor Florent Loiseleur, Arles's was deeply close to the recent works of Jules Hardouin-Mansart's agency whom the master builder Jacque Jaquet, said Beaufleury, had most probably to be inspired of. This construction is an example of the way amateur architects used to work in the conservative circle of provençal nobility.

  15. La editorial Ricordi y su aportación a la publicidad italiana de principios del siglo XX / The publisher Ricordi and his contribution to the Italian advertising early twentieth century

    Directory of Open Access Journals (Sweden)

    Rut Francia Ferrero

    2013-09-01

    Full Text Available El objeto de estudio de la presente investigación es el nacimiento de las campañas publicitarias gráficas orquestadas por la fructífera colaboración entre empresarios, editores e ilustradores entre los siglos XIX y XX en Italia. El estudio se centra en la Casa Editorial Ricordi porque fue la creadora e impulsora del moderno cartel artístico y publicitario italiano, con un vasta producción de ejemplares, hoy considerados obras maestras del género. La etapa de oro del cartel italiano coincide, no por casualidad, con el predominio técnico y artístico de esta empresa en Italia que nada tenía que envidiar a sus competidoras francesas (como la prestigiosa Imprimerie Chaix parisina, tan querida por Jules Chéret, alemanas o inglesas. El período analizado (1890-1914 es el de mayor actividad y esplendor artístico en las artes gráficas. Son los años de los primeros pasos en el campo de la publicidad. Como en todos los comienzos, abundan las ideas, la energía, la ingenuidad y las ganas de experimentar. Es un tiempo lleno de cambios: la transformación económica, social e industrial que vivió Europa en un lapso tan corto de  tiempo es probablemente la mayor de su historia.The purpose of this research is the birth of graphic advertising campaigns orchestrated by the fruitful collaboration between employers, publishers and illustrators between the nineteenth and twentieth centuries in Italy. The study focuses on the Ricordi publishing house because it was the creator and driving force of the modern Italian poster art and advertising with a vast production of copies, today considered masterpieces of the genre. The golden age of Italian poster coincides, not coincidentally, with the technical and artistic dominance of this company in Italy that had nothing to envy their French competitors (including the prestigious Paris Imprimerie Chaix, so beloved by Jules Cheret, German or England. The period analyzed (1890-1914 is the most active and

  16. Tribute to a Leading Personality of World Horticultural Science

    Directory of Open Access Journals (Sweden)

    Radu E. SESTRAS

    2010-12-01

    Full Text Available Following the proposal of Academic Council of Horticulture Faculty, the Senate of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca accepted nominee Professor Jules Janick for Doctor Honoris Causa award. The title was awarded in festive ceremony on September 30, 2010. Jules Janick, Professor at Purdue University has a long and distinguished career devoted to horticulture in all its facets. In horticultural research, he has made important advances including the genetics of sex determination including the synthesis of heteromorphic sex chromosomes, fireblight resistance, cleistogamy, cucurbitacins, artemisisin production, anthocyanin pigmentation, as well as in vitro metabolite production from somatic embryos and the production of synthetic seed. In crop improvement, he has been associated with the release of 21 scab-resistant apple cultivars, three pear cultivars with tolerance to fireblight, delayed-bolting arugula, crack resistant tomato, and the first release of a pelargonium cultivar from somaclonal variation. Professor Janick has made contributions to the historical aspects of horticulture and explored the relation of art and horticultural technology with special studies on the iconography of Rubus, Cucurbitaceae, and Solanaceae, opening up a new approach to the study of plant diversity, origins, cultivar evolution, and diversity. Professor Janick has been a prolific author and editor in horticulture. He was the editor of HortScience and editor of the Journal of ASHS. He is the founder and editor of both Horticultural Reviews and Plant Breeding Reviews. Since 2002 he has been the science editor of Chronica Horticulturae (ISHS. Janick has edited and produced six proceedings of New Crops symposia since 1990 that have had a deep impact on new crop information. The development of a new crop website has become a major world resource for information on crops. He is the author of the texts Horticultural Science, Plant Science

  17. Anaplastic lymphoma kinase (ALK inhibitors for second-line therapy of non-small cell lung cancer

    Directory of Open Access Journals (Sweden)

    Berghmans T

    2012-12-01

    Full Text Available Thierry Berghmans,1 Myriam Remmelink,2 Ahmad Awada31Clinic of Thoracic Oncology and Department of Intensive Care, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium; 2Department of Pathology, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium; 3Medical Oncology Clinic, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, BelgiumAbstract: Targeted therapies are nowadays a treatment option in metastatic non-small cell lung cancer, for which oncogenic drivers have been identified. The epidermal growth factor-receptor tyrosine kinase inhibitors gefitinib and erlotinib, are the standard of care for patients in whom tumors are presenting with an activating epidermal growth factor-receptor mutation, with new active agents like afatinib reaching clinics in the near future. Other genetic abnormalities have been documented in squamous and non-squamous lung cancer. The EML4–ALK gene fusion is a rare event, occurring in around 5% of lung cancer, quite exclusively in adenocarcinoma with a predominance of young non/light smokers. Detection of ALK-positive tumors is challenging, as there is no gold-standard technique. Fluorescence in situ hybridization is the method used in prospective trials assessing the activity of crizotinib and is recommended by the American FDA. Crizotinib is the first orally active inhibitor of receptor tyrosine kinases, including ALK and ROS1, in clinical practice. Impressive results came from a phase I study and are now confirmed in a large phase II study with response rate of 60%, whatever the number of previous lines of chemotherapy. Other ALK inhibitors are currently in the preclinical phase, and some are showing promising results in early phase I/II studies. This review aims to present the current knowledge on the EML4–ALK gene fusion, the pitfalls for the pathologist and the clinician in searching this abnormality, and to review the existing literature on ALK inhibitors under

  18. Bruxas: figuras de poder Witches: figures of power

    Directory of Open Access Journals (Sweden)

    Paola Basso Menna Barreto Gomes Zordan

    2005-08-01

    Full Text Available As mulheres que tanto a história como a imaginação popular mitificaram como "bruxas" constituem figuras que expurgam as fobias da Contra Reforma. As bruxas foram torturadas e queimadas para sinalizar os perigos de práticas e saberes à margem da Igreja e de outras instituições dominantes na Idade Moderna. Parteiras, curandeiras e carpideiras, as bruxas misturam em seu caldeirão os mistérios da vida e da morte herdados das tradições pagãs. Este artigo percorre textos de historiadores, em especial o de Jules Michelet, que no século XIX construiu a imagem romântica e martirizada da bruxa, e o manual de inquisidores do século XIV, o Malleus Maleficarum, que descreve os poderes da bruxa, sua aliança com o demônio e sua ameaça para o cristianismo. Os discursos instaurados por tais textos constroem tanto a imagem que glorifica a bruxa quanto aquela que a execra, mostrando ambas o potencial transformador de suas práticas e de sua ligação com a sexualidade.The women whom history and popular imagination mythicized as "witches" constitute figures that purge the phobias of the Counter Reformation. Witches were tortured and burned to signal the dangers of practices and knowledge in the margins of the Church and other dominant institutions in the Modern Age. Midwives, healers and weepers, the witches blend in their large kettle the mysteries of life and death inherited from pagan traditions. This paper examines some historians' texts, especially that of Jules Michelet, who created the witch's romantic and martyred image, and the inquisitors' manual Malleus Maleficarum, that describes the witch's powers, her alliance with the demon and her threat to Christianity. These texts establish, through their different discourses, two opposing images: one that glorifies witches and another that execrates them, in order to show the transforming potential of their practices and their connection with sexuality.

  19. « Au fracas de la foudre, les animaux intelligents s'éveillèrent »

    Directory of Open Access Journals (Sweden)

    Agnès Bouvier

    2011-07-01

    Full Text Available Félix Pouchet, dans son Hétérogénie, ou Traité de la génération spontanée qu’il publie en 1859, défend, contre Pasteur et Milne-Edwards, l’idée d’une « force génésique » inhérente à la matière qui aurait présidé à la création et qui continuerait de s’exercer dans la formation et la transformation des espèces. Le livre fait partie des lectures de Flaubert pendant la période de rédaction de Salammbô. Le 5 août 1860, il écrit dans une lettre à madame Jules Sandeau : « J’entremêle mes lectures puniques (qui ne sont pas légères d’autres facéties graves. Je me livre maintenant au volumineux bouquin de mon ami le docteur Pouchet sur les générations spontanées. » C’est la nature de cet entrelacement que nous proposons d’interroger, à travers l’étude génétique d’un passage du chapitre III de Salammbô où Flaubert récrit la cosmogonie phénicienne à la lumière du spontanéisme moderne.Félix Pouchet, in Heterogeny or Spontaneous generation Treatise (1859, argues, against Pasteur and Milne-Edwards, for the existence of a « genesical force » inside matter at the beginning of the universe, still active in the formation and transformation of species. Flaubert read Pouchet’s book when he was writing Salammbô. On August 5th 1860, he wrote to madame Jules Sandeau : « I mingle my Punic readings (which are not light with other serious jokes. I now dedicate myself to my friend doctor Pouchet’s bulky book on spontaneous generations. » This interlacing of archaeology and science is precisely what I will examine in my paper, through the genetic study of a passage of Salammbô (chapter III where Flaubert rewrites the Phoenician cosmogony in the light of modern spontaneism.

  20. Microstructure representation of snow in coupled snowpack and microwave emission models

    Science.gov (United States)

    Sandells, Melody; Essery, Richard; Rutter, Nick; Wake, Leanne; Leppänen, Leena; Lemmetyinen, Juha

    2017-01-01

    This is the first study to encompass a wide range of coupled snow evolution and microwave emission models in a common modelling framework in order to generalise the link between snowpack microstructure predicted by the snow evolution models and microstructure required to reproduce observations of brightness temperature as simulated by snow emission models. Brightness temperatures at 18.7 and 36.5 GHz were simulated by 1323 ensemble members, formed from 63 Jules Investigation Model snowpack simulations, three microstructure evolution functions, and seven microwave emission model configurations. Two years of meteorological data from the Sodankylä Arctic Research Centre, Finland, were used to drive the model over the 2011-2012 and 2012-2013 winter periods. Comparisons between simulated snow grain diameters and field measurements with an IceCube instrument showed that the evolution functions from SNTHERM simulated snow grain diameters that were too large (mean error 0.12 to 0.16 mm), whereas MOSES and SNICAR microstructure evolution functions simulated grain diameters that were too small (mean error -0.16 to -0.24 mm for MOSES and -0.14 to -0.18 mm for SNICAR). No model (HUT, MEMLS, or DMRT-ML) provided a consistently good fit across all frequencies and polarisations. The smallest absolute values of mean bias in brightness temperature over a season for a particular frequency and polarisation ranged from 0.7 to 6.9 K. Optimal scaling factors for the snow microstructure were presented to compare compatibility between snowpack model microstructure and emission model microstructure. Scale factors ranged between 0.3 for the SNTHERM-empirical MEMLS model combination (2011-2012) and 3.3 for DMRT-ML in conjunction with MOSES microstructure (2012-2013). Differences in scale factors between microstructure models were generally greater than the differences between microwave emission models, suggesting that more accurate simulations in coupled snowpack-microwave model systems

  1. Towards an improved and more flexible representation of water stress in coupled photosynthesis-stomatal conductance models; implications for simulated land surface fluxes and variables at various spatiotemporal scales

    Science.gov (United States)

    Egea, G.; Verhoef, A.; Vidale, P. L.; Black, E.; Van den Hoof, C.

    2012-04-01

    Coupled photosynthesis-stomatal conductance (A-gs) models are commonly used in ecosystem models to represent the exchange rate of CO2 and H2O between vegetation and the atmosphere. The ways these models account for water stress differ greatly among modelling schemes. This study provides insight into the impact of contrasting model configurations of water stress on the simulated leaf-level values of net photosynthesis (A), stomatal conductance (gs), the functional relationship among them and their ratio, the intrinsic water use efficiency (A/gs), as soil dries. A simple, yet versatile, normalized soil moisture dependent function was used to account for the effects of water stress on gs, on mesophyll conductance (gm ) and on the biochemical capacity (Egea et al., 2011). Model output was compared to leaf-level values obtained from the literature. The sensitivity analyses emphasized the necessity to combine both stomatal and non-stomatal limitations of A in coupled A-gs models to accurately capture the observed functional relationships A vs. gs and A/gs vs. gs in response to drought. Accounting for water stress in coupled A-gs models by imposing either stomatal or biochemical limitations of A, as commonly practiced in most ecosystem models, failed to reproduce the observed functional relationship between key leaf gas exchange attributes. A quantitative limitation analysis revealed that the general pattern of C3 photosynthetic response to water stress can be represented in coupled A-gs models by imposing the highest limitation strength to mesophyll conductance, then to stomatal conductance and finally to the biochemical capacity. This more realistic representation of soil water stress on the simulated leaf-level values of A and gs was embedded in the JULES (Joint UK Land Environment Simulator; Best et al., 2011), model and tested for a number of vegetation types, for which driving and flux verification data were available. These simulations provide an insight into the

  2. First feedback with the AMMON integral experiment for the JHR calculations

    Directory of Open Access Journals (Sweden)

    Lemaire M.

    2013-03-01

    Full Text Available The innovative design of the next international Material Testing Reactor, the Jules Horowitz Reactor (JHR, induced the development of a new neutron and photon calculation formular HORUS3D/P&N, based on deterministic and stochastic codes and the European nuclear data library JEFF3.1.1. A new integral experiment, named the AMMON experiment, was designed in order to make the experimental validation of HORUS3D. The objectives of this experimental program are to calibrate the biases and uncertainties associated with the HORUS3D/N&P calculations for JHR safety and design calculations, but also the validation of some specific nuclear data (concerning mainly hafnium and beryllium isotopes. The experiment began in 2010 and is currently performed in the EOLE zero-power critical mock-up at CEA Cadarache. This paper deals with the first feedback of the AMMON experiments with 3D Monte Carlo TRIPOLI4©/JEFF3.1.1 calculations.

  3. Tropes of Ascesis and Ascent in Polar Expeditions from Verne to Amundsen

    Directory of Open Access Journals (Sweden)

    Lucia Claudia Fiorella

    2011-04-01

    Full Text Available What we know of polar expeditions coincides with a number of fictional and non fictional representations using different registers: the iconic-technical-scientific, the auto/biographical, the literary/fictional. This paper draws a comparison between texts featuring contrasting views on the character and purposes of polar expeditions, their supposed usefulness and political consequences, and the certification procedures of scientific knowledge, reflecting broader concerns about the idea of progress, the man/environment relation, and international relations. Fictional and non fictional texts are involved in this ideological confrontation in varying degrees of urgency. However, one cannot fail to note ongoing competition between the two, if only for the fact that the explorers’ accounts take pains to produce hallmarks of authenticity, veridicality and reliability in order not to be mixed up with fiction; on the other hand, fiction makes use of mimetic strategies achieving an amazing effect of realism.The contributor offers a thematic reading of ascent-related tropes, focusing on Jules Verne’s Captain Hatteras (1866 as an example of critical optimism in contrast with the apocalyptic Purple Cloud (1901 by M.P. Shiel, as well as with R.E. Amundsen’s My Polar Flight (1925 – which features an optimism that has lost its Promethean overtones and comes closer to the elation for a sporting achievement.

  4. Birth of the science of immunology.

    Science.gov (United States)

    Schmalstieg, Frank C; Goldman, Armond S

    2010-05-01

    The science of immunology emerged in the last of the 19th and the first of the 20th century. Substantial progress in physics, chemistry and microbiology was essential for its development. Indeed, microorganisms became one of the principal investigative tools of the major founders of that science - Louis Pasteur, Robert Koch, Ilya Ilich Metchnikoff, Paul Ehrlich and Jules Bordet. It is pertinent that these pioneering scientists were born when questioning and exploration were encouraged because of the legacies of the previous century of enlightenment. Mentors greatly aided their development. Their discoveries were shaped by their individual personalities. In turn they developed other contributors to the nascent field. Their discoveries included the types of leukocytes, the roles of neutrophils in inflammation and defence, cellular lysis due to complement, the principles of humoral and cellular immunology, passive and active immunization, tissue antigens, anaphylaxis, anaphylactoid reactions and autoimmunity. Their work formed the basis of modern immunology that developed many decades later. Immunology has enormously impacted our understanding of the pathogenesis, diagnosis and treatment of infections, immune-mediated disorders and inflammation. Burgeoning advances forecast further important clinical applications of immunology. Yet, their applications will be problematic because few physicians sufficiently understand the science. We propose that understanding modern immunology requires a grasp of how that science developed - who made the discoveries, how they were made, their successes and failures, their interactions and debates all reveal the foundation of modern immunology.

  5. Pasteur, Pastorians, and the dawn of immunology: the importance of specificity.

    Science.gov (United States)

    Silverstein, A M

    2000-01-01

    Throughout his career, the problems that attracted Louis Pasteur almost invariably involved considerations of specificity of structure and/or of action. Thus, his work on asymmetric crystals showed that chemical form not only specifies crystalline structure, but affects the affinity of ferments as well. In his studies of diseases of silkworms, of beer, and of wine, he could unerringly distinguish with the microscope the specific agents of disease. From this emerged his concept of the specificity of species and against the nonspecificity of spontaneous generation, whence the germ theory of disease. It was in the new field of immunology, however, where the manifestations of an exquisite specificity were most clearly seen. Here, Pasteur's vaccines worked because he chose the specific pathogen in order to induce a specific immunity, and he succeeded each time. But the two most prominent Pastorian successors in immunology, Elie Metchnikoff and Jules Bordet, were not equally successful. Although each contributed significantly to the birth of immunology, each advanced a theory that neglected the principle of specificity and paid a price in consequence. Metchnikoff's phagocytic theory of immunity could not survive the demonstrable specificity of humoral antibodies, while Bordet's physical adsorptive concept of the antibody-cell interaction quickly fell to Paul Ehrlich's demonstration of the stereochemical determination of immunological specificity.

  6. Post-irradiation examination of AlFeNi cladded U 3Si 2 fuel plates irradiated under severe conditions

    Science.gov (United States)

    Leenaers, A.; Koonen, E.; Parthoens, Y.; Lemoine, P.; Van den Berghe, S.

    2008-04-01

    Three full size AlFeNi cladded U 3Si 2 fuel plates were irradiated in the BR2 reactor of the Belgian Nuclear Research Centre (SCK·CEN) under relatively severe, but well defined conditions. The irradiation was part of the qualification campaign for the fuel to be used in the future Jules Horowitz reactor in Cadarache, France. After the irradiation, the fuel plates were submitted to an extensive post-irradiation campaign in the hot cell laboratory of SCK·CEN. The PIE shows that the fuel plates withstood the irradiation successfully, as no detrimental defects have been found. At the cladding surface, a multilayered corrosion oxide film has formed. The U-Al-Si layer resulting from the interaction between the U 3Si 2 fuel and the Al matrix, has been quantified as U(Al,Si) 4.6. It is found that the composition of the fuel particles is not homogenous; zones of USi and U 3Si 2 are observed and measured. The fission gas-related bubbles generated in both phases show a different morphology. In the USi fuel, the bubbles are small and numerous while in U 3Si 2 the bubbles are larger but there are fewer.

  7. Julian B. Rotter (1916-2014).

    Science.gov (United States)

    Strickland, Bonnie R

    2014-01-01

    One of the most influential psychologists of the 20th century, Julian B. Rotter, died at the age of 97 on January 6, 2014, at his home in Mansfield, Connecticut. Jules was born on October 22, 1916, in Brooklyn, New York, the third son of Jewish immigrant parents. As noted in the citation for his American Psychological Association (APA) Award for Distinguished Scientific Contributions, "his pioneering social learning framework...transformed behavioral approaches to personality and clinical psychology. He integrated the concepts of expectancy and reinforcement and built an enduring early bridge between the psychology of learning and its diverse social, clinical, and personality applications. His seminal studies of the variable of internal versus external locus of control provided the foundation for years of prolific research on choice and perceived control in several disciplines...Julian Rotter, by his writing, teaching, and personal example,...profoundly changed theory and practice in the field" (American Psychologist, 1989, p. 625). He was devoted to his family and shared his insights, his empathy, his compassion, and his admirable social conscience with them, as he did with his myriad friends and students.

  8. ATV Cargo Integration Safety Certification Process

    Science.gov (United States)

    Garbellini, L.; Heimann, T. J.

    2005-12-01

    A large number of manned modules are being progressively launched to the International Space Station (ISS) and integrated on-orbit, required to be operated and maintained over long on-orbit stay time, supported by periodical servicing and supply.The European Space Agency (ESA), together with its several industrial aerospace contractors such as Alcatel Alenia Space, is deeply involved in development of space systems hardware, in planning and execution of mission operations, logistics and supply to ISS of consumables, payloads, scientific experiments, orbital replacement units up to station modules and infrastructures, as needed by the ISS utilization cycles. In this frame safety plays a significant role to assure that the safety of the systems is preserved throughout the ISS exploitation phase. This paper summarizes methods and requirements for the safety certification process being implemented to dry cargo integration and accommodation in Jules Verne, the 1st flight of the Automated Transfer Vehicle (ATV), one of the major ESA contributions to the utilization of ISS.

  9. International Systems Integration on the International Space Station

    Science.gov (United States)

    Gerstenmaier, William H.; Ticker, Ronald L.

    2007-01-01

    Over the next few months, the International Space Station (ISS), and human spaceflight in general, will undergo momentous change. The European Columbus and Japanese Kibo Laboratories will be added to the station joining U.S. and Russian elements already on orbit. Columbus, Jules Vernes Automated Transfer Vehicle (ATV) and Kibo Control Centers will soon be joining control centers in the US and Russia in coordinating ISS operations and research. The Canadian Special Purpose Dexterous Manipulator (SPDM) will be performing extra vehicular activities that previously only astronauts on EVA could do, but remotely and with increased safety. This paper will address the integration of these international elements and operations into the ISS, both from hardware and human perspectives. Interoperability of on-orbit systems and ground control centers and their human operators from Europe, Japan, Canada, Russia and the U.S. pose significant and unique challenges. Coordination of logistical support and transportation of crews and cargo is also a major challenge. As we venture out into the cosmos and inhabit the Moon and other planets, it's the systems and operational experience and partnership development on ISS, humanity's orbiting outpost that is making these journeys possible.

  10. Simeprevir for the treatment of hepatitis C virus infection

    Directory of Open Access Journals (Sweden)

    Izquierdo L

    2014-08-01

    Full Text Available Laure Izquierdo,1 François Helle,1 Catherine François,1,2 Sandrine Castelain,1,2 Gilles Duverlie,1,2 Etienne Brochot1,2 1Virology Research Unit, Jules Verne University of Picardie, 2Department of Virology, Amiens University Hospital, Amiens, France Abstract: Simeprevir (TMC435, Olysio™, a second-generation hepatitis C virus (HCV protease inhibitor, has been recently approved for the treatment of genotype 1 chronic hepatitis C in combination with pegylated interferon and ribavirin. This molecule has very different characteristics from first-generation protease inhibitors. Results from trials show that simeprevir is highly effective and safe, with few adverse events. We discuss the specific features of this new treatment option for HCV infection, in terms of in vitro data, pharmacological data, and clinical trials. We also discuss the impact of Q80K polymorphism at baseline. Studies evaluating interferon-free regimens with simeprevir are ongoing. Future combinations of two or more direct-acting antiviral agents, targeting different viral enzymes and with synergistic antiviral effects, will be approved, allowing treatment of pan-genotypic HCV with optimized sustained virologic responses. Simeprevir will undoubtedly be part of future treatment strategies. Keywords: simeprevir, protease inhibitor, direct-acting antiviral agent, hepatitis C virus

  11. Key Challenges and New Trends in Battery Research (2011 EFRC Forum)

    Energy Technology Data Exchange (ETDEWEB)

    Tarascon, Jean Marie (University de Picardie Jules Verne, France)

    2011-05-26

    Jean-Marie Tarascon, Professor at the University de Picardie Jules Verne, France, was the fourth speaker in the May 26, 2011 EFRC Forum session, "Global Perspectives on Frontiers in Energy Research." In his presentation, Professor Tarascon recounted European basic research activates in electrical energy storage. The 2011 EFRC Summit and Forum brought together the EFRC community and science and policy leaders from universities, national laboratories, industry and government to discuss "Science for our Nation's Energy Future." In August 2009, the Office of Science established 46 Energy Frontier Research Centers. The EFRCs are collaborative research efforts intended to accelerate high-risk, high-reward fundamental research, the scientific basis for transformative energy technologies of the future. These Centers involve universities, national laboratories, nonprofit organizations, and for-profit firms, singly or in partnerships, selected by scientific peer review. They are funded at $2 to $5 million per year for a total planned DOE commitment of $777 million over the initial five-year award period, pending Congressional appropriations. These integrated, multi-investigator Centers are conducting fundamental research focusing on one or more of several “grand challenges” and use-inspired “basic research needs” recently identified in major strategic planning efforts by the scientific community. The purpose of the EFRCs is to integrate the talents and expertise of leading scientists in a setting designed to accelerate research that transforms the future of energy and the environment.

  12. The GNC Measurement System for the Automated Transfer Vehicle

    Science.gov (United States)

    Roux, Y.; da Cunha, P.

    The Automated Transfer Vehicle (ATV) is a European Space Agency (ESA) funded spacecraft developed by EADS Space Transportation as prime contractor for the space segment together with major European industrial partners, in the frame of the International Space Station (ISS). Its mission objective is threefold : to supply the station with fret and propellant, to reboost ISS to a higher orbit and to dispose of waste from the station. The ATV first flight, called Jules Verne and planned on 2005, will be the first European Vehicle to perform an orbital rendezvous. The GNC Measurement System (GMS) is the ATV on board function in charge of the measurement data collection and preconditioning for the navigation, guidance and control (GNC) algorithms. The GMS is made up of hardware which are the navigation sensors (with a certain level of hardware redundancy for each of them), and of an on-board software that manages, monitors and performs consistency checks to detect and isolate potential sensor failures. The GMS relies on six kinds of navigation sensors, used during various phases of the mission : the gyrometers assembly (GYRA), the accelerometers assembly (ACCA), the star trackers (STR), the GPS receivers, the telegoniometers (TGM) and the videometers (VDM), the last two being used for the final rendezvous phase. The GMS function is developed by EADS Space Transportation together with other industrial partners: EADS Astrium, EADS Sodern, Laben and Dasa Jena Optronik.

  13. A Selenological History of Lunar Poetics

    Science.gov (United States)

    von Chamier-Waite, C. T.

    2016-01-01

    The Moon. Centuries of human inquiry have engaged this mysterious object. The Moon embodies history, philosophy, cosmology, and passions; the nature of love, persecution, and our capacity for the sublime. This review considers a body of research on lunar poetics done for a series of artworks by the author. It will look at a few select writings that have profoundly influenced our epistemological, ontological, and poetic knowledge of the universe with the Moon as a central theme. Centered in the early seventeenth century at the time of Kepler and Galileo, this query follows the tendrils of lunar influences in both the sciences and literature that emanate from these two figures, forwards and backwards in time. Science, politics, theology, and the arts intertwine in this investigation. The works reviewed link the philosophy of Aristotle and the poetry of Lucian of Samosata to findings by Leonardo Da Vinci, Copernicus, Jules Verne, and others. The chosen philosophers have been selected because of their significant contributions to selenology and lunar poetics, and each of the figures reviewed have the honor of a namesake crater upon the Moon.

  14. Contested Waterlines: The Wave-Line Theory and Shipbuilding in the Nineteenth Century.

    Science.gov (United States)

    Ferreiro, Larrie D; Pollara, Alexander

    2016-04-01

    Ship hydrodynamics in the nineteenth century was dominated by John Scott Russell's wave-line theory. Russell, a prominent British shipbuilder and scientist, argued that wavemaking was the primary source of resistance for ships, and that by designing ships according to trigonometric curves and proportions (the wave line) this resistance could effectively be eliminated. From the 1840s to the 1880s, shipbuilders such as John Willis Griffiths, Donald McKay and George Steers designed their clipper ships (like Sea Witch and Flying Cloud) and yachts (America) with wave-line hulls, while authors like Jules Verne referenced Russell's theory. The wave line slowly faded after William Froude developed his laws of ship resistance. The article examines how Russell's theory became accepted by technical experts and the wider public to become the most widely known ship hydrodynamic theory of the 1800s-a reminder of how a persuasive idea can take hold of an entire profession, and even the public, for a long time.

  15. Projections of population-based twinning rates through the year 2100.

    Science.gov (United States)

    Oleszczuk, J J; Keith, D M; Keith, L G; Rayburn, W F

    1999-11-01

    To present the first compilation of population-based twinning rates published after the year 1990 and to project population-based twinning rates through the year 2100. We searched the Internet-based MEDLINE database for articles published after 1990 in which population-based twinning rates were described. We used population-based data from national statistical authorities from Australia, Austria, Canada, Finland, Hong Kong, Israel, Japan, Norway, Singapore and Sweden, published by Y. Imaizumi in a recent article. U.S. figures were based on data from the National Center for Health Statistics. Annual growth rates of twinning were calculated and graphed, making the assumption that these rates would remain constant throughout the next century. Our report presents the most recent population-based twinning rates. When projected through the year 2015, twinning rates reach figures that could best be described as derived from a Jules Verne novel: Sweden, in this model, would have four times more twin than singleton births. We strongly suggest that physicians reexamine their patterns of prescribing ovulation-inducing agents, which carry a greatly increased risk of multiple pregnancy.

  16. LITERATURA DE EXPLORAÇÕES E AVENTURAS: AS “VIAGENS EXTRAORDINÁRIAS” DE JÚLIO VERNE

    Directory of Open Access Journals (Sweden)

    Oswaldo Bueno Amorim Filho

    2008-12-01

    Full Text Available RESUMÉ: La forte croissance des études humanistes-culturelles au monde, dans les dernières decennies, a provoquéune rennaissance d’une ancienne collaboration entre la géographie et la littérature. Cet essai introductoirea pour objectif recouvrer une des manifestations littéraires le plus proches de la géographie, c’est a dire,la “littérature de voyages, explorations et aventures”.Cette littérature a eu son apogée dans l’Europe du XIXème siècle, surtout en Allemagne, au Royaume-Uni et en France. Dans ce dernier pays, l’écrivain Jules Verne est le meilleur exemple de ce type delittérature, avec sa grande collection de Voyages extraordinaires. Le but de cet essai est d’analyser lesconnexions de cette collection littéraire avec la géographie.

  17. The Cincinnati Observatory as a Research Instrument for Undergraduate Research

    Science.gov (United States)

    Abel, Nicholas; Regas, Dean; Flateau, Davin C.; Larrabee, Cliff

    2016-06-01

    The Cincinnati Observatory, founded in 1842, was the first public observatory in the Western Hemisphere. The history of Cincinnati is closely intertwined with the history of the Observatory, and with the history of science in the United States. Previous directors of the Observatory helped to create the National Weather Service, the Minor Planet Center, and the first astronomical journal in the U.S. The Cincinnati Observatory was internationally known in the late 19th century, with Jules Verne mentioning the Cincinnati Observatory in two of his books, and the Observatory now stands as a National Historic Landmark.No longer a research instrument, the Observatory is now a tool for promoting astronomy education to the general public. However, with the 11" and 16" refracting telescopes, the Observatory telescopes are very capable of collecting data to fuel undergraduate research projects. In this poster, we will discuss the history of the Observatory, types of student research projects capable with the Cincinnati Observatory, future plans, and preliminary results. The overall goal of this project is to produce a steady supply of undergraduate students collecting, analyzing, and interpreting data, and thereby introduce them to the techniques and methodology of an astronomer at an early stage of their academic career.

  18. Around Kepler's "Dream"

    CERN Document Server

    Luminet, Jean-Pierre

    2011-01-01

    Johann Kepler (1571-1630) is sometimes considered as a precursor of science-fiction novels with the writing of "Somnium, sive opus posthumum of astronomia lunaris". In this work published posthumously in 1634 by his son Ludwig, Kepler intends to defend the Copernican doctrine by detailing the perception of the world for an observer located on the Moon. Although Kepler was not the first to write the fantastic account of a voyage from the Earth to the Moon and "pass around a message", we show here that his "Dream" is made conspicuous under many aspects. Firstly, his author is one of the most remarkable minds of the history of sciences. Secondly, the "Dream" constitutes the missing link between the texts of pure imagination by Lucian of Samosata (IInd c. AD), and the fantasy novels based on scientific discoveries by Jules Verne, at the end of XIXth century. In the third place, the complete text presents an extraordinary structure in encased accounts, built on several series of explanatory notes drafted with the ...

  19. Analysis Of The ATV1 Re-Entry Using Near-UV Spectroscopic Data From The ESA/NASA Multi-Instrument Aircraft Observation Campaign

    Science.gov (United States)

    Lohle, Stefan; Marynowski, Thomas; Knapp, Andreas; Wernitz, Ricarda; Lips, Tobias

    2011-05-01

    The first Automated Transfer Vehicle (ATV1) named Jules Verne was launched in March 2009 to carry over seven tons of experiments, fuel, water, food and other supplies to the International Space Station (ISS) orbiting at about 350 km. Attached to the ISS, it served as an extension to the space station, giving extra space for the six astronauts and cosmonauts who will ultimately form the permanent ISS Crew. On September 29, 2009, a controlled de-orbit maneuver lead the spacecraft to enter the Earth's atmosphere over the south pacific ocean. The following destructive re-entry was observed by two aircraft equipped with a wide variety of imaging and spectroscopic instruments. In this paper, we present quantitative results from the near-UV spectroscopic measurements acquired aboard an experimental DC-8 aircraft operated by NASA. The wavelength range of observation allows a determination of temperatures from radiation and the investigation of atomic radiation with respect to the identification of the destructive process. Furthermore, the excitation temperatures of chromium give an insight into the explosive events occurring during re-entry. Analysing the continuum of the measured spectra, the Planck radiation temperature is fitted to the data. These temperatures indicate that most of the radiating parts are titanium alloys, i.e. the outer structure of ATV1. All results within this paper are compared to a simulated break-up scenario and related to basic results from other experimenters which allows drawing an overall scenario for this destructive re-entry.

  20. CONTRAPONTOS À NOÇÃO DE EPISTEMOLOGIA DE SARTRE

    Directory of Open Access Journals (Sweden)

    Daniel Ramos dos Santos

    2011-02-01

    Full Text Available O presente texto tem como objetivo, em um primeiro momento, fazer uma breveapresentação da noção de epistemologia na obra O Ser e o Nada de Jean-Paul Sartre para, apartir daí, colocar em evidência alguns conceitos importantes para tal noção, tais como ‘cogitopré-reflexivo’, ‘cogito reflexivo’ e principalmente a afirmação feita por Sartre de que toda teoriado conhecimento pressupõe uma metafísica. Em um segundo momento, serão apresentados doiscontrapontos teóricos à noção epistemológica sartreana. O primeiro contraponto será feito pormeio do empirismo clássico de Alfred Jules Ayer e o segundo por meio da noção deEpistemologia Naturalizada tal como concebida por Willard Van Orman Quine. Neste segundocaso o contraponto se estabelecerá tanto à noção de um cogito pré-reflexivo e reflexivo, como àafirmação de que toda teoria do conhecimento pressupõe uma metafísica.

  1. Public medical shows.

    Science.gov (United States)

    Walusinski, Olivier

    2014-01-01

    In the second half of the 19th century, Jean-Martin Charcot (1825-1893) became famous for the quality of his teaching and his innovative neurological discoveries, bringing many French and foreign students to Paris. A hunger for recognition, together with progressive and anticlerical ideals, led Charcot to invite writers, journalists, and politicians to his lessons, during which he presented the results of his work on hysteria. These events became public performances, for which physicians and patients were transformed into actors. Major newspapers ran accounts of these consultations, more like theatrical shows in some respects. The resultant enthusiasm prompted other physicians in Paris and throughout France to try and imitate them. We will compare the form and substance of Charcot's lessons with those given by Jules-Bernard Luys (1828-1897), Victor Dumontpallier (1826-1899), Ambroise-Auguste Liébault (1823-1904), Hippolyte Bernheim (1840-1919), Joseph Grasset (1849-1918), and Albert Pitres (1848-1928). We will also note their impact on contemporary cinema and theatre.

  2. Use of the HadGEM2 climate-chemistry model to investigate interannual variability in methane sources

    Science.gov (United States)

    Hayman, Garry; O'Connor, Fiona; Clark, Douglas; Huntingford, Chris; Gedney, Nicola

    2013-04-01

    emission totals for the different years and source sectors using sector and species-specific scaling factors based on the annual trends given in various EDGAR time series: (a) version 4.2 for all species (except NMVOCs) and version 4.1 for NMVOCs; (b) v3.2. This approach was also applied to the emissions from aviation (only for oxides of nitrogen) and international shipping. Biomass burning: Month-specific emission inventories are available from the Global Fire Emissions Database (GFED, v3.1) for the years 1997 to 2009 [7]. The emissions were rescaled to give the same decadal mean as used in the Hadley Centre's earlier HadGEM2 runs (25 Tg CH4 per annum). Other: Sources such as termites and hydrates for methane were taken from the GEIA website and the dataset of Fung et al. [8]. The datasets contain a single annual cycle, which was assumed to apply for all years. For CH4, there are also emissions from wetlands. These were either based on the dataset of Fung et al. [8] or derived from the JULES (Joint UK Land Earth Simulator) land surface model [9, 10]. The standard version of JULES uses a simple methane wetland emission parameterization, developed and tested by [11] for use at large spatial scales. The surface concentrations from the different model runs have been compared to surface atmospheric CH4 measurements. In addition, growth rates have been derived. These comparisons will be reported and used to assess the contribution of different methane sources to the interannual variations in the methane growth rate. References [1] Dlugokencky, E.J., et al.: Global atmospheric methane: budget, changes and dangers. Philosophical Transactions of the Royal Society A, 369, 2058-2072; doi: 10.1098/rsta.2010.0341, 2011. [2] Forster, P., et al.: Changes in Atmospheric Constituents and in Radiative Forcing. In: Climate Change 2007: The Physical Science Basis. Contribution of Working Group I to the Fourth Assessment Report of the Intergovernmental Panel on Climate Change [Solomon, S., D

  3. Operational tools and applications of EO satellite data to retrieve surface fluxes in semi-arid countries

    Science.gov (United States)

    Tanguy, Maliko

    The objective of the thesis is to develop and evaluate useful tools and applications of Earth Observation (EO) satellite data to estimate surface fluxes in semi-arid countries. In a first part (Chapter 4), we assess the performance of a new parameterisation scheme of ground heat flux (G) to be used in remote sensing (RS) evapotranspiration (ET) estimation methods. The G-parameterisation optimized with AMMA flux data performs well and improves the sensible heat flux (H) and ET retrieved by means of the triangle method (Jiang & Islam, 2001). In a second part (Chapter 5), the triangle method is compared with ET estimated by means of a land surface model (JULES). An attempt is made to calibrate JULES using the triangle method through Monte Carlo simulations, but the two methods supply rather different results, indicating that further intercomparison tasks should be carried out to assess the performance of RS-based algorithms and land surface models in estimating the components of the land surface energy balance. Chapter 6 presents a set of operational examples for retrieving surface fluxes using RS data. The first example is the study of temporal evolution of ET-maps in Western Africa under monsoonal influence. In a second example, we apply the new scheme proposed in Chapter 4 to retrieve and analyse the long term evolution (2000-2009) of the surface energy balance components, G, H and ET at several sites of the Segura Basin (S-E Spain) using MODIS-Terra data (land surface temperature and NDVI). Temporal and spatial distribution of evapotranspiration reveals different controls on ET. (Chapter 6). In the last example, MODIS-Aqua Sea Surface Temperature (SST) is used to validate a mathematical model to retrieve surface fluxes in a Mediterranean coastal lagoon (Mar Menor, S-E Spain). El objetivo de esta tesis es de desarrollar y evaluar herramientas y aplicaciones de la teledetección para estimar flujos de superficie en zonas semiáridas. En una primera parte (Cap

  4. New linear plasma devices in the trilateral euregio cluster for an integrated approach to plasma surface interactions in fusion reactors

    Energy Technology Data Exchange (ETDEWEB)

    Unterberg, B., E-mail: b.unterberg@fz-juelich.de [Institut fuer Energieforschung - Plasmaphysik, Forschungszentrum Juelich GmbH, Association EURATOM- Forschungszentrum Juelich, D-52425 Juelich (Germany); Jaspers, R. [Science and Technology of Nuclear Fusion, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven (Netherlands); Koch, R. [Laboratoire de Physique des Plasmas/Laboratorium voor Plasmafysica, ERM/KMS, EURATOM-Association, B-1000 Brussels (Belgium); Massaut, V. [SCK-CEN, Belgian Nuclear Research Centre, EURATOM-Association, Boeretang 200, 2400 Mol (Belgium); Rapp, J. [FOM-Institute for Plasma Physics Rijnhuizen, Association EURATOM-FOM, PO Box 1207, 3430 BE Nieuwegein (Netherlands); Reiter, D.; Kraus, S.; Kreter, A.; Philipps, V.; Reimer, H.; Samm, U.; Scheibl, L.; Schweer, B. [Institut fuer Energieforschung - Plasmaphysik, Forschungszentrum Juelich GmbH, Association EURATOM- Forschungszentrum Juelich, D-52425 Juelich (Germany); Schuurmans, J.; Uytdenhouwen, I. [SCK-CEN, Belgian Nuclear Research Centre, EURATOM-Association, Boeretang 200, 2400 Mol (Belgium); Al, R.; Berg, M.A. van den; Brons, S.; Eck, H.J.N. van; Goedheer, W.J. [FOM-Institute for Plasma Physics Rijnhuizen, Association EURATOM-FOM, PO Box 1207, 3430 BE Nieuwegein (Netherlands)

    2011-10-15

    New linear plasma devices are currently being constructed or planned in the Trilateral Euregio Cluster (TEC) to meet the challenges with respect to plasma surface interactions in DEMO and ITER: i) MAGNUM-PSI (FOM), a high particle and power flux device with super-conducting magnetic field coils which will reach ITER-like divertor conditions at high magnetic field, ii) the newly proposed linear plasma device JULE-PSI (FZJ), which will allow to expose toxic and neutron activated target samples to ITER-like fluences and ion energies including in vacuo analysis of neutron activated samples, and iii) the plasmatron VISION I, a compact plasma device which will be operated inside the tritium lab at SCK-CEN Mol, capable to investigate tritium plasmas and moderately activated wall materials. This contribution shows the capabilities of the new devices and their forerunner experiments (Pilot-PSI at FOM and PSI-2 Juelich at FZJ) in view of the main objectives of the new TEC program on plasma surface interactions.

  5. Modelling of thermal hydraulics in a KAROLINA calorimeter for its calibration methodology validation

    Directory of Open Access Journals (Sweden)

    Luks Aleksandra

    2016-12-01

    Full Text Available Results of numerical calculations of heat exchange in a nuclear heating detector for nuclear reactors are presented in this paper. The gamma radiation is generated in nuclear reactor during fission and radiative capture reactions as well as radioactive decay of its products. A single-cell calorimeter has been designed for application in the MARIA research reactor in the National Centre for Nuclear Research (NCBJ in Świerk near Warsaw, Poland, and can also be used in the Jules Horowitz Reactor (JHR, which is under construction in the research centre in Cadarache, France. It consists of a cylindrical sample, which is surrounded by a gas layer, contained in a cylindrical housing. Additional calculations had to be performed before its insertion into the reactor. Within this analysis, modern computational fluid dynamics (CFD methods have been used for assessing important parameters, for example, mean surface temperature, mean volume temperature, and maximum sample (calorimeter core temperature. Results of an experiment performed at a dedicated out-of-pile calibration bench and results of numerical modelling validation are also included in this paper.

  6. Cadastral map supersession acording new instructions

    Directory of Open Access Journals (Sweden)

    Alena Berková

    2009-11-01

    Full Text Available Digital form o cadastral map exists on 36 % of cadastral areas of the Czech republic. Contemporary rate of dogitalizationis 2-3 % of total number cadastral areas anually. In Jule 2007 was approved by goverment decree N. 871/2007 document of Czechoffice for surveying, mapping and cadstre, that assesments deadline of cadstral maps digitalization in the year 2015. Financingof digitalization has to solve amendent of act N. 634/2004 Sb. of administrative charges. As interium solution offered COSMC Parcelorientation maps, that are free available on internet from March 2008. There are rastr images of cadastral maps in datum S-JTSKsuccesive complemented with parcel defonition points. One of reason insufficient rate of digitalization was uncertainty of reworkingtechnology of maps. These maps cover about 70 % territory of the Czech republic. From 1.1.2008 stands the new instruction, thatestablishs technology approach for cadastral map supersession. The article descibes curiosity, where was find erreneouslydetermination of property boundry, without solving next relationships.

  7. Las obsesiones antes de Freud: historia y clínica

    Directory of Open Access Journals (Sweden)

    Rafael Huertas

    2014-12-01

    Full Text Available Se analiza el significado del concepto de “obsesión” en el alienismo del siglo XIX. Desde el punto de vista clínico, la descripción de Esquirol fue completada por otros autores (Jules Falret, Legrand du Saulle. En el ámbito de la reflexión psicopatológica, el alienismo francés, con el delirio emotivo de Morel o la psicastenia de Janet, defendió la teoría emocional, frente al trastorno intelectual propuesto por los médicos alemanes. Finalmente, se insiste en la importancia del marco cultural en la aparición de los síntomas obsesivos y de su interpretación. En este sentido, se estudian las relaciones de los escrúpulos religiosos con la melancolía o la aparición de categorías diagnósticas sometidas a los códigos y mentalidades fin-de-siècle.

  8. [Altruistic public servant or heroic genius? The propagated image of provincial and academic directors of bacteriological laboratories in Belgium (ca. 1900-1940)].

    Science.gov (United States)

    Onghena, Sofie

    2009-01-01

    At the end of the nineteenth century provincial bacteriological institutes were established in Belgium--in Liège, Mons, Namur and Brussels--in order to combat epidemics, to promote preventive medicine and to pursue the successful research of Louis Pasteur and Robert Koch. Similar laboratories existed at the universities of Ghent, Louvain and Brussels. The image building played an important role for both kinds of institutes, as bacteriology in pioneering phase had to be publicly confirmed as a new, valuable discipline. However, the directors of provincial and academic institutes--with the same academic training though--were awarded with different qualities at their jubilees, fitting with the purposes and the self-image of their respective institutions, either provincial authorities or universities. The image of academic directors was guided by academic decorum: Emile van Ermengem, Edmond Destrée and Joseph Denys were represented as savants, solely devoted to pure science and paternally educating young researchers, notwithstanding the fact that their laboratories had humanitarian merits as well. On the other hand, the discourse on the first provincial directors--Ernest Malvoz, Martin Herman, Achille Haibe--emphasized their altruistic commitment and their solid work for the provincial government. Jules Bordet, a internationally rewarded scientist, professor and provincial director of the Pasteur Institute in Brussels, was celebrated with both sorts of discourses.

  9. The jobs behind the science

    CERN Multimedia

    Stefania Pandolfi

    2015-01-01

    The HR Recruitment Unit has launched a series of short videos designed to attract the very best talents that CERN needs to pursue its cutting-edge research. CERN is very well-known for hiring physicists, but engineers, technicians and professionals working in diverse sectors in our 21 Member States are less aware that they too can have a once-in-a-lifetime opportunity to work in this unique place.   (Video: Jules Ordan, Jacques Fichet/CERN.) “The Jobs behind the Science” is the first of a series of videos presented by the Recruitment Unit of the HR Department's Talent Acquisition Group, aiming to promote CERN’s image as an employer of choice for all science, technology, engineering and mathematics (STEM) professions. “Difficulties in recruiting in the STEM market are a Europe-wide problem, and CERN is particularly affected by a common, well-established misconception: that this is a place only for elite physicists and engineers,” exp...

  10. Experimental reactor regulation: the nuclear safety authority's approach; Le controle des reacteurs experimentaux: la demarche de l'Autorite de surete nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Rieu, J.; Conte, D.; Chevalier, A. [Autorite de Surete Nucleaire, 75 - Paris (France)

    2007-07-15

    French research reactors can be classified into 6 categories: 1) critical scale models (Eole, Minerve and Masurca) whose purpose is the study of the neutron production through the fission reaction; 2) reactors that produce neutron beams (Orphee, and the high flux reactor in Grenoble); 3) reactors devoted to safety studies (Cabri, Phebus) whose purpose is to reproduce accidental configurations of power reactors in reduced scale; 4) experimental reactors (Osiris, Phenix) whose purpose is the carrying-out of irradiation experiments concerning nuclear fuels or structure materials; 5) teaching reactors (Ulysse, Isis); and 6) reactors involved in defense programs (Caliban, Prospero, Apareillage-B). We have to note that 3 research reactors are currently being dismantled: Strasbourg University's reactor, Siloe and Siloette. Research reactors in France are of different types and present different hazards. Even if methods of control become more and more similar to those of power reactors, the French Nuclear Safety Authority (ASN) works to allow the necessary flexibility in the ever changing research reactor field while ensuring a high level of safety. Adopting the internal authorizations for operations of minor safety significance, under certain conditions, is one example of this approach. Another challenge in the coming years for ASN is to monitor the ageing of the French research reactors. This includes periodic safety reviews for each facility every ten years. But ASN has also to regulate the new research reactor projects such as Jules Horowitz Reactor, International Thermonuclear Experimental Reactor, which are about to be built.

  11. "Pop" psychoanalysis, kitsch, and the "as if" theater: further notes on Peter Shaffer's Equus.

    Science.gov (United States)

    Gifford, S

    1976-01-01

    This paper is intended as an examination of Dr. Stamm's (1975) paper and of Dr. Jules Glenn's discussion of Peter Shaffer's previous work. Its premise is the futility of subjecting Equus to a traditional psychoanalytic investigation, as a product of the playwright's unconscious, when the play represents a skillful, highly conscious use of analytic cliches to manipulate the audience. This phenomenon, however, and the play's great popularity prompt some reflections on the nature of kitsch, or false art, and its differences from authentic drama. The experience of kitsch can be identified when the spectator feels coerced by exaggerated, unconvincing theatrical devices, and fails to experience genuine empathy with the characters in a play. In the experience of authentic tragedy there is some element of voluntary surrender, of suspension of disbelief with full consent of will, as in the Aristotelian concept of catharsis. Shaffer's play is discussed as an illustration of this distinction and its relation to pseudoemotionality, the impostor syndrome, and the "as if" personality. In conclusion, the play's failure to evoke a genuine emotional response is explained by interpreting Equus as an "as if" tragedy.

  12. Revisiting Cotard’s Syndrome: Illustration of Two Psychiatric Clinical Cases

    Directory of Open Access Journals (Sweden)

    Lídia Sousa

    2016-07-01

    Full Text Available Background: Cotard’s Syndrome (CS is a rare and severe neuropsychiatric condition in which the central feature is the existence of nihilistic delusions. Controversy has ensued about the precise clinical picture Jules Cotard meant to describe and attempts have been made, more recently, not only to clarify the terminology, but also to define different types of this syndrome and explore its biological basis. Aims: We intend to briefly review the terminology, etiology, epidemiology and differential diagnosis of this syndrome, based on two clinical cases. Methods: Bibliographic search conducted through the electronic databases Medline and Gallica (French National Library, consultation of clinical records and direct interviews with the patients. Results and Conclusions: Typically the patients diagnosed with CS manifest the delusional idea that they are dying or already dead. However, it is also possible that they deny the existence of only some parts of their own body, or the functioning of some organs, and they may even sometimes deny the existence of the external world. We illustrate the case of a 66-year-old woman, diagnosed with bipolar affective disorder, admitted in the context of a severe depressive episode with psychotic symptoms, compatible with CS type II and the case of a young male aged 22, admitted due to a first  psychotic episode with schizophrenia like characteristics, presenting with nihilistic delusions compatible with CS type I.

  13. A perspective on disability and rehabilitation

    Directory of Open Access Journals (Sweden)

    D. J. Mothabeng

    2007-02-01

    Full Text Available This paper is written in honor of the memory of the late Jules Rothstein, editor in chief “emeritus” of the Physical Therapy (the journal of the American Physical Therapy Association - APTA who passed away on the 27-08-2005. It is  fitting to dedicate a paper on disability to Dr. Rothstein, as he himself likened  disability with the identity of physiotherapy. A paper focusing on disability at this time might be the wake up call needed to make physiotherapists heed the African decade of the disabled person, which is more than halfway through. The paper highlights the problem of sparse evidence in rehabilitation and emphasizes the need for an evidence-based approach to rehabilitation. Practical suggestions for the implementation of EBP in rehabilitation using the International Classification of Functioning, Disability (ICF as a framework are proposed. This paper is envisaged to enthuse rehabilitation physiotherapists to embrace EBP, so that their focus is redirected to the ‘eradication of disability’.

  14. De l’idéologie d’État au film d’éducation : itinéraire comparé de la France, de l’Italie et des États-Unis dans les années vingt From State Ideology to the Educational Film: comparative itineraries of France, Italy and the United States in the Twenties

    Directory of Open Access Journals (Sweden)

    Christel Taillibert

    2009-10-01

    Full Text Available The political faces of the French Republic, Mussolini’s Fascist Italy and the United States of America in the Twenties are totally distinct. Nevertheless, the way these countries used educational and teaching films at the time was the product of the same intention: the transmission of the founding values of their respective systems of government. These values are, in France, the inheritance of the Enlightenment, strengthened by the republican ideals stemming from the French Revolution and the state educational model created by Jules Ferry; in Italy, Mussolini’s Nationalist Postulate, and his desire to form a “New Man”, a “regenerated race” of Italians and in the US, the raising of moral standards and the affirmation of inter-culturalism in the already well implanted notion of the “American Way of Life”. Distributed in schools and educational circles, these films, today forgotten, propose a symptomatic example of state propaganda in times of peace.

  15. RJH, a new test reactor in Europe; Le RJH - un nouveau reacteur d'essai en europe

    Energy Technology Data Exchange (ETDEWEB)

    Iracane, D. [CEA Saclay, Dir. de l' Energie Nucleaire (DEN), 91 - Gif sur Yvette (France)

    2005-07-01

    Material test reactors (MTR) are now ageing in Europe and they cannot secure the experimental needs over next decades. In this context, a new MTR, named Jules Horowitz reactor (RJH), operated as an international user-facility, is under development on the Cea's site of Cadarache (France). The design studies will end in 2007, the construction stage will follow and RJH commissioning is scheduled in 2014. Its construction costs are estimated to 500 million euros. RJH is a pool reactor of 100 MWth, its core will be inserted in a pressurized vessel with a primary circuit assuring water flow through forced convection. The core inlet-outlet temperature is about 25-40 Celsius degrees. RJH core is designed to use a high density - low enrichment UMo nuclear fuel (8 gU/cm{sup 3}, enrichment rate: 19.75%). Experimental devices located in the core will benefit from neutron fluxes ranging from 2.5 10{sup 14} n/cm{sup 2}.s to 5.10{sup 14} n/cm{sup 2}.s (E > 1 MeV). RJH is designed to manage simultaneously 10 experiments in the core and as many in the reflector. (A.C.)

  16. Analysis and discussion on reports of additional safety assessment of nuclear installations with respect to the Fukushima accident; Analyse et commentaire des rapports d'evaluation complementaire de la surete des installations nucleaires au regard de l'accident de Fukushima

    Energy Technology Data Exchange (ETDEWEB)

    Sene, Monique; Sene, Raymond

    2011-11-15

    This document proposes an analysis of the reports made by the different operators of nuclear installations within the frame of a safety audit of the French nuclear installations with respect to the Fukushima accident. Operators (mainly AREVA, the CEA and EDF) were asked to perform additional safety assessments. In a first part, the conclusions of EDF reports are analysed regarding the seismic risk, the flooding risk, the situation of some specific sites (Fessenheim, Tricastin), other phenomena (rains, winds), loss of electricity supplies and of cooling systems, severe accidents, hydrogen issue, chemical hazards, subcontractors, crisis management. Conclusions of AREVA reports are analysed for the different sites (Tricastin, La Hague, MELOX factory, Romans factory). Conclusions of CEA reports are analysed for the different concerned installations (ATPu, Masurca, Osiris, Phenix, Jules Horowitz reactor). A second part proposes a global analysis of EDF's additional safety assessment reports regarding earthquake, flooding, other extreme natural phenomena, loss of electricity supplies and cooling system, subcontracting conditions, crisis management, and radiation protection organisation. AREVA's and CEA's reports are then analysed in terms of report structure and content, and for the different concerned sites

  17. Altruïstisch ambtenaar of heroïsch genie? Het gepropageerde beeld van provinciale en academische directeurs van bacteriologische laboratoria in België (ca. 1900-1940

    Directory of Open Access Journals (Sweden)

    Sofie Onghena

    2009-12-01

    Full Text Available Altruistic public servant or heroic genius? The propagated image of provincial and academic directors of bacteriological laboratories in Belgium (ca. 1900-1940 At the end of the nineteenth century provincial bacteriological institutes were established in Belgium – in Liège, Mons, Namur and Brussels – in order to combat epidemics, to promote preventive medicine and to pursue the successful research of Louis Pasteur and Robert Koch. Similar laboratories existed at the universities of Ghent, Louvain and Brussels. The image building played an important role for both kinds of institutes, as bacteriology in pioneering phase had to be publicly confirmed as a new, valuable discipline. However, the directors of provincial and academic institutes – with the same academic training though – were awarded with different qualities at their jubilees, fitting with the purposes and the self-image of their respective institutions, either provincial authorities or universities. The image of academic directors was guided by academic decorum: Emile van Ermengem, Edmond Destrée and Joseph Denys were represented as savants, solely devoted to pure science and paternally educating young researchers, notwithstanding the fact that their laboratories had humanitarian merits as well. On the other hand, the discourse on the first provincial directors – Ernest Malvoz, Martin Herman, Achille Haibe – emphasized their altruistic commitment and their solid work for the provincial government. Jules Bordet, internationally rewarded scientist, professor and provincial director of the Pasteur Institute in Brussels, was celebrated with both sorts of discourses.

  18. A Spectral Evaluation of Models Performances in Mediterranean Oak Woodlands

    Science.gov (United States)

    Vargas, R.; Baldocchi, D. D.; Abramowitz, G.; Carrara, A.; Correia, A.; Kobayashi, H.; Papale, D.; Pearson, D.; Pereira, J.; Piao, S.; Rambal, S.; Sonnentag, O.

    2009-12-01

    Ecosystem processes are influenced by climatic trends at multiple temporal scales including diel patterns and other mid-term climatic modes, such as interannual and seasonal variability. Because interactions between biophysical components of ecosystem processes are complex, it is important to test how models perform in frequency (e.g. hours, days, weeks, months, years) and time (i.e. day of the year) domains in addition to traditional tests of annual or monthly sums. Here we present a spectral evaluation using wavelet time series analysis of model performance in seven Mediterranean Oak Woodlands that encompass three deciduous and four evergreen sites. We tested the performance of five models (CABLE, ORCHIDEE, BEPS, Biome-BGC, and JULES) on measured variables of gross primary production (GPP) and evapotranspiration (ET). In general, model performance fails at intermediate periods (e.g. weeks to months) likely because these models do not represent the water pulse dynamics that influence GPP and ET at these Mediterranean systems. To improve the performance of a model it is critical to identify first where and when the model fails. Only by identifying where a model fails we can improve the model performance and use them as prognostic tools and to generate further hypotheses that can be tested by new experiments and measurements.

  19. Managing the risk of agricultural drought in Africa

    Science.gov (United States)

    Quaife, T. L.; Black, E.; Brown, M.; Greatrex, H.; Maidment, R.; Mookerjee, A.; Tarnavsky, E.

    2015-12-01

    Farmers in Africa are highly vulnerable to variability in the weather - especially to drought. Robust and timely information on drought risk can enable farmers to take action to increase yields. Such information also forms the basis of financial instruments, such as weather index insurance. Monitoring weather conditions is, however, difficult in Africa because of the heteorogeneity of the climate, and the sparcity of the ground-observing network. Remotely sensed data (for example satellite-based rainfall estimates) are an alternative to ground observations - but only if the algorithms have skill and the data are presented in a useful form. A more fundamental issue is that the condition of the land surface is affected by factors other than rainfall. The evolving risk of agricultural drought is thus determined by the properties of the land surface, the contemporaneous soil moisture and the risk of rainfall deficits. We present a prototype agricultural decision support tool, based on the JULES land-surface model, driven with ensembles of meteorological driving data, which encompass the uncertainty in rainfall. We discuss the application of the tool for designing and implementing drought insurance in Ghana and Zambia - illustrated with real examples of weather index insurance schemes that are already active.

  20. Continuous renal replacement therapy for acute renal failure in patients with cancer: a well-tolerated adjunct treatment

    Directory of Open Access Journals (Sweden)

    Rebecca Fischler

    2016-08-01

    Full Text Available Abstract Introduction – Acute renal failure (ARF has a poor prognosis in patients with cancer requiring intensive care unit (ICU admission. Our aim is finding prognostic factors for hospital mortality in patients with cancer with ARF requiring renal replacement therapy (RRT. Methods – In this retrospective study, all patients with cancer with ARF treated with continuous venovenous filtration (CVVHDF in the ICU of the Institut Jules Bordet, between January 1st 2003 and December 31st 2012, were included in the study.Results – 103 patients are assessed: men/women 69/34, median age 62 years, solid/haematologic tumours 68/35, median SAPS II 56. Mortality rate was 63%. Seven patients required chronic renal dialysis. After multivariate analysis, two variables were statistically associated with hospital mortality : more than one organ failure (including kidney (OR 5.918 ; 95% CI 2.184 – 16.038 ; p<0,001 and low albumin level (OR 3.341; 95% CI 1.229 – 9.077; p=0,02. Only minor complications related to CVVHDF have been documented.Conclusions – Despite the poor prognosis associated with ARF, CVVHDF is an effective and tolerable renal replacement technique in patients with cancer admitted to the ICU. Multiple organ failure and hypoalbuminemia, two independent prognostic factors for hospital mortality have to be considered when deciding for introducing RRT.

  1. Identification and characterization of a LTR retrotransposon from the genome of Cyprinus carpio var. Jian.

    Science.gov (United States)

    Cao, Liping; Yin, Guojun; Cao, Zheming; Bing, Xuwen; Ding, Weidong

    2016-06-01

    A Ty3/gypsy-retrotransposon-type transposon was found in the genome of the Jian carp (Cyprinus carpio var. Jian) in a previous study (unpublished), and was designated a JRE retrotransposon (Jian retrotransposon). The full-length JRE retrotransposon is 5126 bp, which includes two long terminal repeats of 470 bp at the 5' end and 453 bp at the 3' end, and two open reading frames between them: 4203 bp encoding the group-specific antigen (GAG) and polyprotein (POL). The pol gene has a typical Ty3/gypsy retrotransposon structure, and the gene order is protease, reverse transcriptase, RNase H, and integrase (PR-RT-RH-IN). A phylogenetic analysis of the pol gene showed that it has similarities of 40.7, 40, and 32.8 %, to retrotransposons of Azumapecten farreri, Mizuhopecten yessoensis, and Xiphophorus maculatus, respectively. Therefore, JRE might belong to the JULE retrotransposon family. The copy number of the JRE transposon in the genome of the Jian carp is 124, determined with real-time quantitative PCR. The mRNA of the JRE retrotransposon is expressed in five Jian carp tissues, the liver, kidney, blood, muscle, and gonad, and slightly higher in the kidney and liver than in the other tissues.

  2. Large-Scale Variation in Forest Carbon Turnover Rate and its Relation to Climate - Remote Sensing vs. Global Vegetation Models

    Science.gov (United States)

    Carvalhais, N.; Thurner, M.; Beer, C.; Forkel, M.; Rademacher, T. T.; Santoro, M.; Tum, M.; Schmullius, C.

    2015-12-01

    While vegetation productivity is known to be strongly correlated to climate, there is a need for an improved understanding of the underlying processes of vegetation carbon turnover and their importance at a global scale. This shortcoming has been due to the lack of spatially extensive information on vegetation carbon stocks, which we recently have been able to overcome by a biomass dataset covering northern boreal and temperate forests originating from radar remote sensing. Based on state-of-the-art products on biomass and NPP, we are for the first time able to study the relation between carbon turnover rate and a set of climate indices in northern boreal and temperate forests. The implementation of climate-related mortality processes, for instance drought, fire, frost or insect effects, is often lacking or insufficient in current global vegetation models. In contrast to our observation-based findings, investigated models from the Inter-Sectoral Impact Model Intercomparison Project (ISI-MIP), including HYBRID4, JeDi, JULES, LPJml, ORCHIDEE, SDGVM, and VISIT, are able to reproduce spatial climate - turnover rate relationships only to a limited extent. While most of the models compare relatively well to observation-based NPP, simulated vegetation carbon stocks are severely biased compared to our biomass dataset. Current limitations lead to considerable uncertainties in the estimated vegetation carbon turnover, contributing substantially to the forest feedback to climate change. Our results are the basis for improving mortality concepts in global vegetation models and estimating their impact on the land carbon balance.

  3. White matter in aphasia: a historical review of the Dejerines' studies.

    Science.gov (United States)

    Krestel, Heinz; Annoni, Jean-Marie; Jagella, Caroline

    2013-12-01

    The Objective was to describe the contributions of Joseph Jules Dejerine and his wife Augusta Dejerine-Klumpke to our understanding of cerebral association fiber tracts and language processing. The Dejerines (and not Constantin von Monakow) were the first to describe the superior longitudinal fasciculus/arcuate fasciculus (SLF/AF) as an association fiber tract uniting Broca's area, Wernicke's area, and a visual image center in the angular gyrus of a left hemispheric language zone. They were also the first to attribute language-related functions to the fasciculi occipito-frontalis (FOF) and the inferior longitudinal fasciculus (ILF) after describing aphasia patients with degeneration of the SLF/AF, ILF, uncinate fasciculus (UF), and FOF. These fasciculi belong to a functional network known as the Dejerines' language zone, which exceeds the borders of the classically defined cortical language centers. The Dejerines provided the first descriptions of the anatomical pillars of present-day language models (such as the SLF/AF). Their anatomical descriptions of fasciculi in aphasia patients provided a foundation for our modern concept of the dorsal and ventral streams in language processing.

  4. Poe e a contemporaneidade: um coração sempre delator

    Directory of Open Access Journals (Sweden)

    Amodeo, Maria Tereza

    2009-01-01

    Full Text Available Desde o início da história do cinema a obra de Poe constituiu-se como fonte de material para a nova arte. A interface entre literatura e cinema configura-se como uma questão polêmica na cultura contemporânea, o que, em relação à obra de Poe assume contornos muitos específicos e determinantes. A análise dos elementos constitutivos da literariedade do conto “O coração denunciador” orienta a abordagem realizada a respeito da adaptação homônima para o cinema realizada por Jules Dassin em 1941 e da animação da UPA (United Productions of America, de 1953. A reflexão, ao mesmo tempo em que pretende explicitar as novas possibilidades de leitura da literatura na contemporaneidade, evidencia os ecos da obra de Poe ao longo dos tempos

  5. The explorer as hero: ‘Le Fidèle Apatou’ in the French wilderness

    Directory of Open Access Journals (Sweden)

    Kenneth M. Bilby

    2004-07-01

    Full Text Available Reconstructs the life story and activities of the Aluku Maroon Captain Apatu in French Guiana. Author describes how Apatu aligned with and aided French explorer Jules Cerveaux in exploring the Amazon region in the late 1870s, and maintained contacts with other French colonial figures. Partly because his role and achievements in colonial expansion were valued by the French, Apatu became an important intermediary between the French and the Aluku Maroons. Author further outlines how Apatu due to these French contacts, and also a journey to Paris, adapted to and assimilated French culture, although he maintained his sense of Aluku identity. He sketches the context of the French-Aluku contacts through Apatu, discussing how Apatu's political position and ambitions sometimes met with distrust and tensions with fellow-Aluku. He further indicates that Aluku alliance with the French probably was intended as a protection against intrusions of the rivaling Ndyuka Maroons. Apatu maintained his important position and function as intermediary between French and other whites on the one hand, and the Aluku on the other up to his death in 1908. Author pays particular attention to how Apatu, and after him other Aluku, absorbed "Frenchness" while maintaining an Aluku identity. This, he argues, has remained relevant up to the present, in light of assimilation policies by the French in French Guiana, increasingly affecting the Aluku since the 1970s and threatening their Maroon culture.

  6. Modeling Feedbacks between Biogenic Emissions and Air Chemistry from Site to Globe

    Science.gov (United States)

    Butler, T. M.; Grote, R.

    2014-12-01

    We present the implementation of a new model describing light dependent emission of volatile organic compounds (BVOC) that derives isoprenoid production directly from the electron transport potential and consumption from photosynthesis. Photosynthesis information requirements are designed to be met by many recent land-surface models that apply the Farquhar assimilation scheme, e.g. JULES or CLM. The new approach has the advantages that 1) the commonly observed decrease of (isoprene) emission with increasing CO2 air concentration is considered by the competition on energy between photosynthesis and emission processes, and 2) air pollution impacts may be considered as inducing emissions by activating emission enzymes as well as decreasing substrate supply from photosynthesis, and 3) many environmental drivers of BVOC emissions are implicitly considered in the description of plant photosynthesis and phenology, reducing the demand for species-specific emission parameters. We investigate the parameter sensitivity of the suggested model as well as the sensitivity of emissions to a range of environmental conditions with a particular focus on CO2 responses. We present evaluation at the site level and compare the model with other approaches. Finally, we demonstrate the implementation into a coupled global-air chemistry model and discuss the requirements to appropriately parameterize plant functional types.

  7. Status of the MeLoDIE experiment, an advanced device for the study of the irradiation creep of LWR cladding with full online capabilities

    Energy Technology Data Exchange (ETDEWEB)

    Guimbal, P. [CEA, DEN, DER, Jules Horowitz Reactor, F-13108 St-Paul-lez-Durance (France); Huotilainen, S.; Taehtinen, S. [VTT Technical Research Centre of Finland, Materials performance division, Espoo, FI-02044 VTT (Finland); Thellier, G. [CEA, DEN, DRSN, OSIRIS Reactor, F-91191 Gif-sur-Yvette (France); Villard, J.F. [CEA, DEN, DER, Instrumentation, Sensors and Dosimetry Laboratory, F-13108 St- Paul-lez-Durance (France)

    2015-07-01

    As a prototype of future instrumented material experiments in the Jules Horowitz Reactor (JHR), the MELODIE project was launched in 2009 by the CEA in collaboration with VTT. Being designed as a biaxial creep experiment with online capability, MELODIE is able to apply an online-controlled biaxial loading on a LWR clad sample up to 120 MPa and to perform an online measurement of its biaxial deformation. An important experimental challenge was to perform reliably accurate measurements under the high nuclear heat load of in-core locations while keeping within their tight space. For that purpose, specific sensors were co-designed with and built by IFE Halden. Manufacturing of the MELODIE components was completed one year ago. The complexity of its in-pile section and of the pressurization system requested a step-by-step tuning of the setup. The toughest part of this process dealt with the Diameter gauge which required a partial redesign to take into account unexpected and unwanted electromagnetic interactions with the hosting device. Final cold performance tests of the on-board instrumentation will be presented. The MELODIE device is now ready and irradiation should start in OSIRIS reactor this spring. (authors)

  8. Bimatoprost in the treatment of eyelash hypotrichosis

    Directory of Open Access Journals (Sweden)

    Simon K Law

    2010-04-01

    Full Text Available Simon K LawJules Stein Eye Institute, University of California, Los Angeles, California, USAAbstract: Eyelashes hypotrichosis is a condition indicated by an inadequate amount of eyelashes. Hypertrichosis of eyelashes, characterized by excessive eyelash growth, is a regular phenomenon associated with ophthalmic prostaglandin and prostamide analogs. Recently, the US Food and Drug Administration approved Latisse® (bimatoprost 0.03% solution, identical to the ophthalmic solution for glaucoma treatment, for increasing eyelash length, thickness and darkness in patients with hypotrichosis of the eyelashes. When prostaglandin and prostamide analogs interact with the prostanoid receptors in the hair follicle, this most likely stimulates the resting follicles (telogen phase to growing follicles (anagen phase. Prostaglandin and prostamide analogs may also prolong the anagen phase of eyelashes, leading to an increase of eyelash length. Although bimatoprost is effective in promoting increased growth of healthy eyelashes and adnexal hairs, its effectiveness in patients with eyelash alopecia areata is debatable and its protective effect is not yet studied in patients with eyelash loss secondary to radiation or chemotherapy. Bimatoprost is generally safe when applied to the base of the eyelashes at the lid margin with minimum side effects. However, other ocular or systemic side effects associated with ophthalmic prostaglandin and prostamide analogs may occur when instilled on the surface of the eye, and patients must be informed and monitored.Keywords: bimatoprost, Latisse, prostaglandin, prostamide, eyelash, hypotrichosis

  9. A doctoral thesis about Carol Davila written in Paris in 1936.

    Science.gov (United States)

    Rogozea, Liliana; Dumitrascu, Dinu I; Triff, Dorin; Leasu, Florin; Dumitraşcu, Dan L

    2014-01-01

    Carol Davila, the father of the Romanian modern medicine, made decisive contributions to the development of health sciences in the Romanian Principalities in the last decades of the nineteenth century. The merit of his scientific work was recognized beyond the borders of his country. His life (not devoid of anecdotic instances and unknown episodes) and especially his work have aroused considerable interest among numerous medical historians. This paper presents a historical study elaborated in France, but until recently ignored, dedicated to the biography of Carol Davila. It concerns the medical doctoral thesis (State Diploma) elaborated by Joseph Adler (born 1910 in Botoşani, Romania) under the supervision of professor Maxime Laignel-Lavastine, whose interest in Romania is well-known. Professor Laignel-Lavastine held the office of Secretary General of the International Society of History of Medicine (ISHM), founded in 1921, (replaced in this position by another French professor with links to Romania: Jules Guiart). The thesis comprises 48 pages and an exhaustive bibliography. It represents a token of the appreciation given to Davila's achievements by Europe's medical community.

  10. Measurement of photon flux with a miniature gas ionization chamber in a Material Testing Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Fourmentel, D., E-mail: damien.fourmentel@cea.fr [CEA, DEN, DER, Instrumentation Sensors and Dosimetry Laboratory, Cadarache, F-13108 St-Paul-Lez-Durance (France); Filliatre, P.; Villard, J.F.; Lyoussi, A. [CEA, DEN, DER, Instrumentation Sensors and Dosimetry Laboratory, Cadarache, F-13108 St-Paul-Lez-Durance (France); Reynard-Carette, C. [Aix-Marseille Université, LISA EA 4672, cedex 20, Marseille 13397 (France); Carcreff, H. [CEA, DEN, DRSN, Saclay, F-91191 Gif-sur-Yvette (France)

    2013-10-01

    Nuclear heating measurements in Material Testing Reactors (MTR) are crucial for the design of the experimental devices and the prediction of the temperature of the hosted samples. Nuclear heating in MTR materials (except fuel) is mainly due to the energy deposition by the photon flux. Therefore, the photon flux is a key input parameter for the computer codes which simulate nuclear heating and temperature reached by samples/devices under irradiation. In the Jules Horowitz MTR under construction at the CEA Cadarache, the maximal expected nuclear heating levels will be about 15 to 18 W g{sup −1} and it will be necessary to assess this parameter with the best accuracy. An experiment was performed at the OSIRIS reactor to combine neutron flux, photon flux and nuclear heating measurements to improve the knowledge of the nuclear heating in MTR. There are few appropriate sensors for selective measurement of the photon flux in MTR even if studies and developments are ongoing. An experiment, called CARMEN-1, was conducted at the OSIRIS MTR and we used in particular a gas ionization chamber based on miniature fission chamber design to measure the photon flux. In this paper, we detail Monte-Carlo simulations to analyze the photon fluxes with ionization chamber measurements and we compare the photon flux calculations to the nuclear heating measurements. These results show a good accordance between photon flux measurements and nuclear heating measurement and allow improving the knowledge of these parameters.

  11. Chercher querelle : l’Enquête sur l’évolution littéraire en procès

    Directory of Open Access Journals (Sweden)

    Jean Rime

    2015-12-01

    Full Text Available La critique a souvent relevé – mais sans toujours s’y attarder – la part batailleuse de l’Enquête sur l’évolution littéraire de Jules Huret, publiée en 1891 dans L’Écho de Paris puis en volume chez Charpentier. Dans le sillage de plusieurs travaux récents qui éclairent les contraintes matérielles, pragmatiques voire poétiques des deux genres journalistiques de l’enquête et de l’interview d’écrivain, cet article étudie comment le texte de Huret vectorise ou attise les querelles interpersonnelles, puis comment, dans sa réception ou dans le décentrage du journal vers le livre, le projet même de Huret prête à controverse, mettant en cause un système médiatique qui modifie le sens de l’action littéraire.

  12. Los proyectos del arquitecto francés Mansart de Sagonne para los canales del Ebro y del Manzanares (1768

    Directory of Open Access Journals (Sweden)

    Cachau, Ph.

    2001-03-01

    Full Text Available La llegada del arquitecto francés Jacques Hardouin-Mansart de Sagonne (1711-1778, nieto del gran arquitecto de Luis XIV Jules Hardouin-Mansart, a Madrid durante el verano de 1768 provocó la evolución, poco más o menos voluntaria, según los casos, de unos proyectos de arquitectura o de ingeniería que la administración del rey Carlos III había descuidado desde hacía años. Si esa llegada constituye un episodio totalmente desconocido de la historia de los canales de España por los autores españoles, su análisis permite no obstante medir el interés que tenían unos ingenieros franceses para un país —España— muy descuidado en aquella época y muy atrasado en el plano de las comunicaciones interiores. Sobre todo, es muy instructivo comparar la política de ambos países —Francia y España— ligados por un Pacto de Familia, en cuanto a las concesiones de privilegios para la construcción y la explotación de canales de navegación.…

  13. Un viaje al interior de la lectura con Julio Verne

    Directory of Open Access Journals (Sweden)

    Ma. Begoña Carretero Gómez

    2008-01-01

    Full Text Available Este trabajo se ha centrado en la lectura de textos de ciencia ficción en las clases de ciencias. El objetivo más importante de esta experiencia ha sido conseguir que los alumnos desarrollen la capacidad de relacionar conceptos que aparecen en la lectura con los conocimientos adquiridos previamente en clase. Como bien dice Loscertales y Núñez (1997 los alumnos de nuestro sistema educativo son los que configuran el trabajo del profesor, el cual deberá poner en práctica todos los recursos a su alcance para adecuar el proceso de enseñanza-aprendizaje a los intereses, necesidades, y características del alumnado. Por ello la idea de acudir a la lectura de textos de ciencia ficción sería una buena forma de hacer este proceso más atractivo.Es muy importante acercar la ciencia y hacerla más accesible. La ciencia ficción ayuda a fomentar el interés por las ciencias estimulando la curiosidad del alumnado, por lo que utilizarla en las clases Biología ha sido una buena estrategia para conseguir aproximar la ciencia y mejorar la capacidad lectora del alumnado. Para llevarla a cabo se ha elegido la novela “Viaje al centro de la Tierra” de Jules Verne.

  14. Un viaje al interior de la lectura con Julio Verne

    Directory of Open Access Journals (Sweden)

    Carretero Gómez, Mª.B

    2008-09-01

    Full Text Available Este trabajo se ha centrado en la lectura de textos de ciencia ficción en las clases de ciencias. El objetivo más importante de esta experiencia ha sido conseguir que los alumnos desarrollen la capacidad de relacionar conceptos que aparecen en la lectura con los conocimientos adquiridos previamente en clase. Como bien dice Loscertales y Núñez (1997 los alumnos de nuestro sistema educativo son los que configuran el trabajo del profesor, el cual deberá poner en práctica todos los recursos a su alcance para adecuar el proceso de enseñanza-aprendizaje a los intereses, necesidades, y características del alumnado. Por ello la idea de acudir a la lectura de textos de ciencia ficción sería una buena forma de hacer este proceso más atractivo. Es muy importante acercar la ciencia y hacerla más accesible. La ciencia ficción ayuda a fomentar el interés por las ciencias estimulando la curiosidad del alumnado, por lo que utilizarla en las clases Biología ha sido una buena estrategia para conseguir aproximar la ciencia y mejorar la capacidad lectora del alumnado. Para llevarla a cabo se ha elegido la novela “Viaje al centro de la Tierra” de Jules Verne.

  15. From imagination to innovation%想像出创新

    Institute of Scientific and Technical Information of China (English)

    郭慕孙

    2002-01-01

    @@ 上古时代人们就想起飞、想上月球.15世纪意大利人Leonardo da Vinci设计了机械翅膀,但由于科技水平所限,没有成功,5个世纪以后才有现代的飞机.中国人早年发明了火药,可是多用于制作花炮,有的炮仗能升空,直到20世纪后期,人类才根据同一原理研制出火箭,将人运载到了月球.海底的龙王庙是《西游记》中的想像,法国小说家Jules Verne在《海底两万里》中对海底的描述有某种程度的科学预见,但直到20世纪初期潜水艇才问世,使海底资源的勘测和应用方兴未艾.

  16. Formaldehyde from GOME-2

    Science.gov (United States)

    Comyn-Platt, Edward; Hewson, Will; Bösch, Hartmut; Barkley, Mike

    2014-05-01

    Isoprene is the most abundant non-methane biogenic volatile organic compound (BVOC) emitted into the atmosphere with emissions roughly equal to global methane emissions from all sources. Isoprene strongly influences the oxidation capacity in the troposphere hence influences levels of methane and tropospheric ozone, and is also a precursor to secondary organic aerosol. Isoprene, therefore, plays a significant role in radiative forcing and determining Earth's climate trends. However, the exact mechanisms of isoprene emission from vegetation are poorly understood and current land-surface models often use different parameterisation and meteorological fields to drive such schemes. Furthermore, isoprene emissions measurements are rare and are difficult to extrapolate to regional and continental scales thus resulting in large uncertainties in the total global emissions. Formaldehyde (HCHO) is formed as an intermediate product during the isoprene oxidation process and can be used as a proxy for isoprene emission. Global satellite observations of formaldehyde are now available from a number of satellite sensors which offer a unique ability to study isoprene emissions over large regions. Here, we use formaldehyde observations from the Global Ozone Monitoring Experiment 2 (GOME-2) instrument retrieved with the University of Leicester retrieval (Hewson et al. 2013) to: 1) test state-of-the-art model calculations using the GEOS-CHEM global transport model; 2) investigate the key drivers for regional year-to-year anomalies in formaldehyde (or isoprene) emissions and 3) assess the ability of current land surface models (MEGAN, JULES) to reproduce the observed anomalies and their dependence on climate variations.

  17. Honors

    Science.gov (United States)

    Anonymous

    2012-10-01

    Many AGU members are among the American Meteorological Society's (AMS) 2013 honorary members, awardees, lecturers, and fellows. Among the AMS honorary members is Susan Solomon, the Ellen Swallow Richards Professor of Atmospheric Chemistry and Climate Science at the Massachusetts Institute of Technology (MIT). Dennis Hartmann, of the University of Washington, Seattle, is the recipient of AMS's Carl-Gustaf Rossby Research Medal "for significant contributions to the synthesis of knowledge of radiative and dynamical processes leading to a deeper understanding of the climate system." R. Alan Plumb, professor of meteorology at MIT, receives the Jule G. Charney Award "for fundamental contributions to the understanding of geophysical fluid dynamics, stratospheric dynamics, chemical transport, and the general circulation of the atmosphere and oceans." The Verner E. Suomi Award has been given to Richard Johnson, professor of atmospheric science at Colorado State University, Fort Collins, "for exquisite design of rawinsonde networks in field campaigns and insightful analysis of interactions between convective clouds and the largescale atmospheric circulation." W. Kendall Melville, professor of oceanography at the Scripps Institution of Oceanography, University of California, San Diego, has been awarded the Sverdrup Gold Medal Award "for pioneering contributions in advancing knowledge on the role of surface wave breaking and related processes in air-sea interaction." AMS announced that Laurence Armi, also a professor of oceanography at Scripps, is recipient of the Henry Stommel Research Award "for his deeply insightful studies of stratified flow, his pioneering work on boundary mixing and other turbulent mechanisms."

  18. The interannual variability of Africa's ecosystem productivity: a multi-model analysis

    Directory of Open Access Journals (Sweden)

    U. Weber

    2009-02-01

    Full Text Available We are comparing spatially explicit process-model based estimates of the terrestrial carbon balance and its components over Africa and confront them with remote sensing based proxies of vegetation productivity and atmospheric inversions of land-atmosphere net carbon exchange. Particular emphasis is on characterizing the patterns of interannual variability of carbon fluxes and analyzing the factors and processes responsible for it. For this purpose simulations with the terrestrial biosphere models ORCHIDEE, LPJ-DGVM, LPJ-Guess and JULES have been performed using a standardized modeling protocol and a uniform set of corrected climate forcing data.

    While the models differ concerning the absolute magnitude of carbon fluxes, we find several robust patterns of interannual variability among the models. Models exhibit largest interannual variability in southern and eastern Africa, regions which are primarily covered by herbaceous vegetation. Interannual variability of the net carbon balance appears to be more strongly influenced by gross primary production than by ecosystem respiration. A principal component analysis indicates that moisture is the main driving factor of interannual gross primary production variability for those regions. On the contrary in a large part of the inner tropics radiation appears to be limiting in two models. These patterns are partly corroborated by remotely sensed vegetation properties from the SeaWiFS satellite sensor. Inverse atmospheric modeling estimates of surface carbon fluxes are less conclusive at this point, implying the need for a denser network of observation stations over Africa.

  19. Photosynthesis sensitivity to climate change in land surface models

    Science.gov (United States)

    Manrique-Sunen, Andrea; Black, Emily; Verhoef, Anne; Balsamo, Gianpaolo

    2016-04-01

    Accurate representation of vegetation processes within land surface models is key to reproducing surface carbon, water and energy fluxes. Photosynthesis determines the amount of CO2 fixated by plants as well as the water lost in transpiration through the stomata. Photosynthesis is calculated in land surface models using empirical equations based on plant physiological research. It is assumed that CO2 assimilation is either CO2 -limited, radiation -limited ; and in some models export-limited (the speed at which the products of photosynthesis are used by the plant) . Increased levels of atmospheric CO2 concentration tend to enhance photosynthetic activity, but the effectiveness of this fertilization effect is regulated by environmental conditions and the limiting factor in the photosynthesis reaction. The photosynthesis schemes at the 'leaf level' used by land surface models JULES and CTESSEL have been evaluated against field photosynthesis observations. Also, the response of photosynthesis to radiation, atmospheric CO2 and temperature has been analysed for each model, as this is key to understanding the vegetation response that climate models using these schemes are able to reproduce. Particular emphasis is put on the limiting factor as conditions vary. It is found that while at present day CO2 concentrations export-limitation is only relevant at low temperatures, as CO2 levels rise it becomes an increasingly important restriction on photosynthesis.

  20. Mitigation of drought negative effect on ecosystem productivity by vegetation mixing

    Science.gov (United States)

    Van den Hoof, Catherine; Lambert, Fabrice

    2016-10-01

    Vegetation diversity and interaction is thought to have a beneficial effect on ecosystem functioning, particularly improving ecosystem resistance to drought. This is of significant importance in the context of a warmer world, as extreme events such as droughts become more likely. Most of the studies performed so far on vegetation interaction are based on observations. Here we use the land surface model JULES to study the potential of vegetation mixing to mitigate the negative effect of drought events on the land surface through interaction, a mechanism which is difficult to study in situ at large scales. Using a set of simulations with mixed and unmixed vegetation, we show that the carbon, water, and energy fluxes are significantly affected by vegetation competition for water resources. The interaction is in general beneficial for the ecosystem carbon assimilation due to a better use of water resources. This benefit is highest when traits between vegetation types concerning resource competition overlap least. For a tree-grass combination, mixing improves carbon assimilation by 5% to 8% during summer. The benefit of mixing increases further under progressively more resource-limited conditions up to an inflection point with a benefit of 14%, after which it falls back to zero under extremely dry conditions. Mixing also tends to reduce the interannual variability of the ecosystem carbon sink and therefore improves the resistance of the ecosystem. Our results highlight the importance of vegetation interaction in climate simulations and impact studies and the potential of vegetation mixing as a mitigation tool.

  1. Vorrei sapere chi sono: Strategie di individuazione del Sé attraverso i feticci

    Directory of Open Access Journals (Sweden)

    Massimo Scotti

    2013-05-01

    Full Text Available L'articolo illustra il ruolo del feticcio nel percorso di appropriazione dell’individualità da parte dell’eroe romanzesco, ricorrendo a esempi letterari dedicati all’età di formazione: non solo storie per l’infanzia, quindi, ma, più ampiamente, vicende in cui il desiderio sostanziale del protagonista si concentra nella “scoperta del Sé”, un Selbst junghiano che cresce e si configura nel suo rapporto con l’Ombra. In questo itinerario i feticci attorniano l’individuo come strumenti, mezzi magici e specchi – non solo della persona ma anche del desiderio stesso. Il discorso si concentra sull’appropriazione dell’identità maschile, sui suoi tranelli e sulle sue insidie. Gli autori presi in considerazione sono Virginia Woolf, Jules Renard, James Matthew Barrie, Joanne K. Rowling e Arthur Schnitzler. Il procedimento critico intende tracciare paralleli fra i classici che hanno forgiato l’immaginario occidentale e le radici più antiche – orientali – delle saghe eroiche (le storie di Gilgamesh; il mito di Indra e Naamuci passando per l’epica cavalleresca (Sir Gawain e il Cavaliere Verde. Un’indicazione illuminante, in questo senso, viene dal critico angloindiano Ananda Coomaraswamy.      

  2. Como se fabricam os anjos?: uma arqueologia do corpo nos manuais escolares de moral e de higiene na França, 1880-1974

    Directory of Open Access Journals (Sweden)

    Jacques Gleyse

    2012-12-01

    Full Text Available A partir de um acervo constituído por 342 manuais escolares de moral e de higiene, o artigo analisa como se constitui um biopoder ou um micropoder no âmbito do discurso escolar. O corpo é ali fabricado, a carne é ali trabalhada como o fora por outras formas de livro (em grego Biblos. Vemos, claramente, aparecer através da arqueologia dos manuais escolares de moral e de higiene na França de fins do século XIX até os anos de 1970 que os preceitos judaico-cristãos, católicos, ou, mais largamente, monoteístas estão vivamente presentes nos manuais. Todavia, é importante sublinhar que esses manuais são parte constitutiva da escola republicana, que, na França, é descrita segundo as leis de 1905, como instituição separada da Igreja e, após as leis elaboradas por Jules Ferry (1880-1882, como instituição laica.

  3. Covariance generation and uncertainty propagation for thermal and fast neutron induced fission yields

    Science.gov (United States)

    Terranova, Nicholas; Serot, Olivier; Archier, Pascal; De Saint Jean, Cyrille; Sumini, Marco

    2017-09-01

    Fission product yields (FY) are fundamental nuclear data for several applications, including decay heat, shielding, dosimetry, burn-up calculations. To be safe and sustainable, modern and future nuclear systems require accurate knowledge on reactor parameters, with reduced margins of uncertainty. Present nuclear data libraries for FY do not provide consistent and complete uncertainty information which are limited, in many cases, to only variances. In the present work we propose a methodology to evaluate covariance matrices for thermal and fast neutron induced fission yields. The semi-empirical models adopted to evaluate the JEFF-3.1.1 FY library have been used in the Generalized Least Square Method available in CONRAD (COde for Nuclear Reaction Analysis and Data assimilation) to generate covariance matrices for several fissioning systems such as the thermal fission of U235, Pu239 and Pu241 and the fast fission of U238, Pu239 and Pu240. The impact of such covariances on nuclear applications has been estimated using deterministic and Monte Carlo uncertainty propagation techniques. We studied the effects on decay heat and reactivity loss uncertainty estimation for simplified test case geometries, such as PWR and SFR pin-cells. The impact on existing nuclear reactors, such as the Jules Horowitz Reactor under construction at CEA-Cadarache, has also been considered.

  4. Intravitreal ranibizumab (Lucentis) in the treatment of retinal angiomatous proliferation (RAP).

    Science.gov (United States)

    Konstantinidis, Lazaros; Mameletzi, Evangelia; Mantel, Irmela; Pournaras, Jean-Antoine; Zografos, Leonidas; Ambresin, Aude

    2009-09-01

    Retinal angiomatous proliferation (RAP) is a distinct variant of neovascular age-related macular degeneration (AMD). The aim of this study is to evaluate the functional and anatomic outcome after intravitreal ranibizumab (Lucentis) treatment in patients with RAP. Prospective study of consecutive patients with newly diagnosed or recurrent RAP treated with intravitreal ranibizumab at the Jules Gonin Eye Hospital between March 2006 and December 2007. Baseline and monthly follow-up visits included best-corrected visual acuity (BCVA), fundus exam and optical coherence tomography. Fluorescein and indocyanine green angiography were performed at baseline and repeated at least every 3 months. Thirty-one eyes of 31 patients were treated with 0.5 mg of intravitreal ranibizumab for RAP between March 2006 and December 2007. The mean age of the patients was 82.6 years (SD:4.9). The mean number of intravitreal injections administered for each patient was 5 (SD: 2.4, range 3 to 12). The mean follow up was 13.4 months (SD: 3, range 10 to 22). The baseline mean logMAR BCVA was 0.72 (SD: 0.45) (decimal equivalent of 0.2). The mean logMAR BCVA was improved significantly (P RAP, resulting in visual gain and reduction in macular thickness. Further long-term studies to evaluate the efficacy of intravitreal ranibizumab in RAP are warranted.

  5. Reactors licensing: proposal of an integrated quality and environment regulatory structure for nuclear research reactors in Brazil; Licenciamento de reatores: proposta de uma estrutura regulatoria integrada com abordagem em qualidade e meio ambiente para reatores de pesquisa no Brasil

    Energy Technology Data Exchange (ETDEWEB)

    Serra, Reynaldo Cavalcanti

    2014-07-01

    A new integrated regulatory structure based on quality and integrated issues has been proposed to be implemented on the licensing process of nuclear research reactors in Brazil. The study starts with a literature review about the licensing process in several countries, all of them members of the International Atomic Energy Agency. After this phase it is performed a comparative study with the Brazilian licensing process to identify good practices (positive aspects), the gaps on it and to propose an approach of an integrated quality and environmental management system, in order to contribute with a new licensing process scheme in Brazil. The literature review considered the following research nuclear reactors: Jules-Horowitz and OSIRIS (France), Hanaro (Korea), Maples 1 and 2 (Canada), OPAL (Australia), Pallas (Holand), ETRR-2 (Egypt) and IEA-R1 (Brazil). The current nuclear research reactors licensing process in Brazil is conducted by two regulatory bodies: the Brazilian National Nuclear Energy Commission (CNEN) and the Brazilian Institute of Environment and Renewable Natural Resources (IBAMA). CNEN is responsible by nuclear issues, while IBAMA by environmental one. To support the study it was applied a questionnaire and interviews based on the current regulatory structure to four nuclear research reactors in Brazil. Nowadays, the nuclear research reactor’s licensing process, in Brazil, has six phases and the environmental licensing process has three phases. A correlation study among these phases leads to a proposal of a new quality and environmental integrated licensing structure with four harmonized phases, hence reducing potential delays in this process. (author)

  6. Analysis of gamma-ray dosimetry experiments in the zero power MINERVE facility

    Energy Technology Data Exchange (ETDEWEB)

    Amharrak, H.; Di Salvo, J.; Lyoussi, A.; Roche, A.; Masson-Fauchier, M.; Bosq, J. C. [CEA, DEN, DER, F-13108 Saint-Paul-lez-Durance (France); Carette, M. [Aix-Marseille Univ., LCP UMR 6264, 13397, Marseille (France)

    2011-07-01

    The objective of this study is to develop nuclear heating measurement methods in zero power experimental reactors. These developments contribute to the qualification of photonics calculation schemes for the assessment of gamma heating in the future Jules Horowitz Material Testing Reactor. This paper presents the analysis of thermoluminescent detector (TLD) experiments in the UO{sub 2} core of the MINERVE Research Reactor at the French Alternative Energies and Atomic Energy Commission center in Cadarache. The experimental sources of uncertainty in the gamma dose have been reduced by improving the measurement conditions and the repeatability of the calibration step for each individual TLD. The interpretation of these measurements needs to take into account the calculation of cavity correction factors related to calibration and irradiation configurations, as well as neutron correction calculations. These calculations are based on Monte Carlo simulations of neutron-gamma and gamma-electron transport coupled particles. The comparison between calculated and measured integral gamma-ray absorbed doses in the aluminum material surrounding the TLD shows that calculations slightly overestimate the measurement, with a calculated versus experimental ratio equal to 1.04 {+-} 5.7 % (k=2). (authors)

  7. Site-level model intercomparison of high latitude and high altitude soil thermal dynamics in tundra and barren landscapes

    Directory of Open Access Journals (Sweden)

    A. Ekici

    2014-09-01

    Full Text Available Modelling soil thermal dynamics at high latitudes and altitudes requires representations of specific physical processes such as snow insulation, soil freezing/thawing, as well as subsurface conditions like soil water/ice content and soil texture type. We have compared six different land models (JSBACH, ORCHIDEE, JULES, COUP, HYBRID8, LPJ-GUESS at four different sites with distinct cold region landscape types (i.e. Schilthorn-Alpine, Bayelva-high Arctic, Samoylov-wet polygonal tundra, Nuuk-non permafrost Arctic to quantify the importance of physical processes in capturing observed temperature dynamics in soils. This work shows how a range of models can represent distinct soil temperature regimes in permafrost and non-permafrost soils. Snow insulation is of major importance for estimating topsoil conditions and must be combined with accurate subsoil temperature dynamics to correctly estimate active layer thicknesses. Analyses show that land models need more realistic surface processes (such as detailed snow dynamics and moss cover with changing thickness/wetness as well as better representations of subsoil thermal dynamics (i.e. soil heat transfer mechanism and correct parameterization of heat conductivity/capacities.

  8. Desired machines: cinema and the world in its own image.

    Science.gov (United States)

    Canales, Jimena

    2011-09-01

    In 1895 when the Lumière brothers unveiled their cinematographic camera, many scientists were elated. Scientists hoped that the machine would fulfill a desire that had driven research for nearly half a century: that of capturing the world in its own image. But their elation was surprisingly short-lived, and many researchers quickly distanced themselves from the new medium. The cinematographic camera was soon split into two machines, one for recording and one for projecting, enabling it to further escape from the laboratory. The philosopher Henri Bergson joined scientists, such as Etienne-Jules Marey, who found problems with the new cinematographic order. Those who had worked to make the dream come true found that their efforts had been subverted. This essay focuses on the desire to build a cinematographic camera, with the purpose of elucidating how dreams and reality mix in the development of science and technology. It is about desired machines and their often unexpected results. The interplay between what "is" (the technical), what "ought" (the ethical), and what "could" be (the fantastical) drives scientific research.

  9. Introductory considerations Athanasios Koukopoulos: The man, the psychiatrist, the original thinker.

    Science.gov (United States)

    Akiskal, Hagop S

    2016-10-21

    What I uttered in Athens moved with apparent emotion [that seem to have not escaped Jules Angst's concern] was spontaneous, except for what is printed in the program book, which has somehow vanished from my office, unlike him with his larger than life figure whose memory will live for as long as he lives in the minds and hearts of all those who were privileged to be his family, colleagues, patients, friends, and… countless others, plus those whose email addresses I cannot locate right now sitting in the sunshine of La Jolla-far away from my loved ones-and wondering what ethnic, genetic and environmental factors-perhaps even several Greek gods combined-to produce the original mind and heart of our Athenian friend who, nonetheless, lived in Rome-and now resting not in the 'atheist' cemetery [it took me 5 minutes to spell this word]-but in our hearts for as long as they will beat-perhaps eventually in another realm, 'from whose bourn'-according to Hamlet-no one has ever returned-that's the promise of the Eternal City-where Athanasios is lying.

  10. Minimally invasive devices for treating lower urinary tract symptoms in benign prostate hyperplasia: technology update

    Directory of Open Access Journals (Sweden)

    Aoun F

    2015-08-01

    Full Text Available Fouad Aoun1, Quentin Marcelis,1,2 Thierry Roumeguère,2 1Department of Urology, Jules Bordet Institute, 2Department of Urology, Erasme Hospital, University Clinics of Brussels, Université Libre de Bruxelles, Brussels, Belgium Abstract: Benign prostatic hyperplasia (BPH represents a spectrum of related lower urinary tract symptoms (LUTS. The cost of currently recommended medications and the discontinuation rate due to side effects are significant drawbacks limiting their long-term use in clinical practice. Interventional procedures, considered as the definitive treatment for BPH, carry a significant risk of treatment-related complications in frail patients. These issues have contributed to the emergence of new approaches as alternative options to standard therapies. This paper reviews the recent literature regarding the experimental treatments under investigation and presents the currently available experimental devices and techniques used under local anesthesia for the treatment of LUTS/BPH in the vast majority of cases. Devices for delivery of thermal treatment (microwaves, radiofrequency, high-intensity focused ultrasound, and the Rezum system, mechanical devices (prostatic stent and urethral lift, fractionation of prostatic tissue (histotripsy and aquablation, prostate artery embolization, and intraprostatic drugs are discussed. Evidence for the safety, tolerability, and efficacy of these “minimally invasive procedures” is analyzed. Keywords: lower urinary tract symptoms (LUTS, benign prostatic hyperplasia (BPH, minimally invasive therapies, new approaches, experimental therapy

  11. RJH seminar; Seminaire RJH du 7 mars 2003

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    This document gathers the slides that have been presented at the Jules Horowitz reactor (RJH) seminar. RJH is the next experimental reactor to be built in France, it will be commissioned in 2013. Its main characteristics are: - power: 100 MW - coolant and moderator: water (input water temperature 25 C, exit water temperature 41 C), down to up flow inside the core - reflector: water and beryllium - maximal enrichment: 19,75 % - mass of {sup 235}U: 21 kg - fast neutron flux (>0,907 MeV): 6,4.10{sup 14} n.cm{sup -2}.s{sup -1} - thermal neutron flux (<0,625 eV) inside the reflector on aluminium block: 7,3.10{sup 14} n.cm{sup -2}.s{sup -1}. The contributions can be classed into 6 topics: 1) presentation of RJH, 2) site studies, 3) its irradiation capacities, 4) calculation tools for its design (neutronic, photonic, fluid flow and heat transfer), 5) materials (aluminium alloys, mechanical resistance, welding, corrosion resistance), and 6) UMo nuclear fuel (fabrication, reprocessing). (A.C.)

  12. Third session: new projects; Session 3: Les Projets nouveaux

    Energy Technology Data Exchange (ETDEWEB)

    Iracane, D. [CEA Saclay, Dir. de l' Energie Nucleaire (DEN), 91 - Gif sur Yvette (France); Dupuy, J.P. [AREVA-Technicatome, 13 - Aix en Provence (France); Perotto, G. [AREVA-Framatome-ANP, 13 - Aix en Provence (France); Ithurralde, G. [Electricite de France (EDF), 13 - Aix en Provence (France); Cabrillat, J.C. [CEA Cadarache, Dir. de l' Energie Nucleaire (DEN), 13 - Saint-Paul-lez-Durance (France); Becle, D. [FRAMATOME, AREVA-FANP, 69 - Lyon (France); Pivet, S. [CEA Bruyeres-le-Chatel, 91 (France); Minguet, J.L. [AREVA-Technicatome, 75 - Paris (France)

    2005-07-01

    The RJH (Jules Horowitz reactor) is a 100 MWth research reactor, cooled and moderated by water, that has been designed to operate with high density (8 g U/cm{sup 3}) and low enrichment fuel (19.75%) uranium molybdenum fuel. Its main neutron performances are expected to be: -) maximum fast neutron flux (E > 0.907 MeV) in the sample: 5.10{sup 14} n/cm{sup 2}/s, -) maximum thermal neutron flux (E < 0.625 eV): 4.10{sup 14} n/cm{sup 2}/s, and -) maximal neutron damage: 16 dpa/year. RJH that will be built on the Cea's site of Cadarache, is scheduled to enter into service in 2014, it will take over the activities of the Osiris reactor and its operating life is planned to be over 50 years long. The Cabri research reactor is located on the Cadarache site, it has been operating since 1962 and is now undergoing important upgrading operations whose aim is to make the facility fit to study the behaviour of new nuclear fuels in accidental situations. The RES test reactor is a facility whose aim is to qualify nuclear fuels and core configurations of existing propulsion reactors onboard of aircraft carriers or submarines and to propose innovative concepts for future propulsion reactors. (A.C.)

  13. Indus script corpora, archaeo-metallurgy and Meluhha (Mleccha)

    CERN Document Server

    Kalyanaraman, Srinivasan

    2012-01-01

    Jules Bloch's work on formation of the Marathi language has to be expanded further to provide for a study of evolution and formation of Indian languages in the Indian language union (sprachbund). The paper analyses the stages in the evolution of early writing systems which began with the evolution of counting in the ancient Near East. A stage anterior to the stage of syllabic representation of sounds of a language, is identified. Unique geometric shapes required for tokens to categorize objects became too large to handle to abstract hundreds of categories of goods and metallurgical processes during the production of bronze-age goods. About 3500 BCE, Indus script as a writing system was developed to use hieroglyphs to represent the 'spoken words' identifying each of the goods and processes. A rebus method of representing similar sounding words of the lingua franca of the artisans was used in Indus script. This method is recognized and consistently applied for the lingua franca of the Indian sprachbund. That th...

  14. Marcel Duchamp and Alfred Jarry

    Directory of Open Access Journals (Sweden)

    Pieter de Nijs

    2016-06-01

    Full Text Available Alfred Jarry (1873-1907 is usually presented as one of Marcel Duchamp’s literary examples. Duchamp however never explicitly named Jarry as such; unlike he did with Jules Laforgue, Raymond Roussel and Jean-Paul Brisset. The reason why Jarry is nevertheless often mentioned as one of Duchamp's major inspirations lies in some – mainly thematic –parallels between their works. Duchamp's ‘amusing physics’ (physique amusante seems to be directly inspired by the pataphysics Jarry introduced in Gestes et opinions du Docteur Faustroll, pataphysicien (1911. The fantastic machines Jarry staged in a novel like Le Surmâle (1902 and in the various stories he wrote for magazines such as La Revue blanche, La Plume and Le Canard sauvage have traces in common with the machineries Duchamp gave shape in - for example - his La Mariee mise à nu par ces célibataires, même. And Duchamp sometimes did refer directly to Jarry, for example to his famous 'merdre'.More interesting though then the thematic parallels are the linguistic experiments Jarry and Duchamp both ventured on, showing some striking similarities.

  15. ECG-cryptography and authentication in body area networks.

    Science.gov (United States)

    Zhang, Zhaoyang; Wang, Honggang; Vasilakos, Athanasios V; Fang, Hua

    2012-11-01

    Wireless body area networks (BANs) have drawn much attention from research community and industry in recent years. Multimedia healthcare services provided by BANs can be available to anyone, anywhere, and anytime seamlessly. A critical issue in BANs is how to preserve the integrity and privacy of a person's medical data over wireless environments in a resource efficient manner. This paper presents a novel key agreement scheme that allows neighboring nodes in BANs to share a common key generated by electrocardiogram (ECG) signals. The improved Jules Sudan (IJS) algorithm is proposed to set up the key agreement for the message authentication. The proposed ECG-IJS key agreement can secure data communications over BANs in a plug-n-play manner without any key distribution overheads. Both the simulation and experimental results are presented, which demonstrate that the proposed ECG-IJS scheme can achieve better security performance in terms of serval performance metrics such as false acceptance rate (FAR) and false rejection rate (FRR) than other existing approaches. In addition, the power consumption analysis also shows that the proposed ECG-IJS scheme can achieve energy efficiency for BANs.

  16. The history of gait analysis before the advent of modern computers.

    Science.gov (United States)

    Baker, Richard

    2007-09-01

    Aristotle (384-322 BCE) can be attributed with the earliest recorded comments regarding the manner in which humans walk. It was not until the renaissance that further progress was made through the experiments and theorising of Giovanni Borelli (1608-1679). Although several scientists wrote about walking through the enlightenment period it was the brothers Willhelm (1804-1891) and Eduard (1806-1871) Weber, working in Leipzig who made the next major contribution based on very simple measurements. Both Jules Etienne Marey (1830-1904), working in France, and Eadweard Muybridge (1830-1904), working in America, made significant advances in measurement technology. These were developed further by Otto Fischer (1861-1917) in collaboration with Willhelm Braune (1831-1892). The major developments in the early twentieth century were in the development of force plates and the understanding of kinetics. The team headed by Verne Inman (1905-1980) and Howard Eberhart (1906-1993) made major advances in America shortly after the Second War. David Sutherland (1923-2006) and Jacquelin Perry pioneered clinical applications in America and Jurg Baumann (1926-2000) in Europe. It was not until the advent of modern computers that clinical gait analysis became widely available.

  17. Figures and institutions of the neurological sciences in Paris from 1800 to 1950. Introduction and Part I: Neuroanatomy.

    Science.gov (United States)

    Clarac, F; Barbara, J-G; Broussolle, E; Poirier, J

    2012-01-01

    We present a short historical review on the major institutions and figures that contributed to make Paris a renowned centre of physiology and neurology during the xixth and the first half of the xxth centuries. We purposely chose to focus on the period 1800-1950, as 1800 corresponds to the development of brain science and 1950 marks the true beginning of neuroscience. Our presentation is divided into four chapters, matching the main disciplines which have progressed and contributed the most to the knowledge we have of the brain sciences: anatomy, physiology, neurology, and psychiatry-psychology. The present article is the first of four parts of this review, which includes an introduction followed by the chapter on neuroanatomy and on anatomo-pathology, which includes biographical sketches of Félix Vicq d'Azyr, François-Xavier Bichat, Franz Joseph Gall, Jean Cruveilhier, Jules Bernard Luys, Paul Broca, Louis Ranvier, André-Victor Cornil, Albert Gombault, Jean Nageotte and René Couteaux.

  18. Chapter 37: alexia and agraphia.

    Science.gov (United States)

    Henderson, Victor W

    2010-01-01

    Studies of alexia and agraphia have played important roles in understanding how complex cognitive functions are related to brain structure and activity. Modern interests in brain-behavior relations began during the second half of the 19th century as an outgrowth of flawed correlative studies by neuroanatomist Franz Gall and subsequent clinical-pathological analyses by Jean-Baptiste Boulliaud on speech and the frontal lobes. In 1856, Louis Victor Marcé drew attention to writing disorders and postulated a cerebral faculty for writing. Following Paul Broca's epochal reports on aphemia, many European physicians investigated reading and writing impairments after brain injury. Albert Pitres published the first detailed description of isolated agraphia, and Adolf Kussmaul identified alexia as an isolated symptom of brain disease. Jules Dejerine in 1892 provided the first clinical-pathological descriptions of pure alexia, and he suggested a key role for the left parietal lobe in reading and writing. In the 20th century, varieties of agraphia or alexia were linked to apraxia (Hugo Liepmann), impaired body image (Josef Gerstmann), spatial misperception, and interhemispheric disconnection. Other analyses focused on error types that defined new clinical syndromes (e.g. deep dyslexia) and provided evidence for cognitive modularity.

  19. The ''Société Géologique du Nord'' (SGN) and Earth Sciences in Northern France; La « Société Géologique du Nord » y las ciencias de la tierra en el norte de Francia

    Energy Technology Data Exchange (ETDEWEB)

    Blieck, A.; Meilliez, F.

    2016-10-01

    The ''Société Géologique du Nord'', located in Lille, in northern France, was founded in 1870, with Jules Gosselet as the first president. It has always been closely connected to the geology department of the Faculty of Sciences of Lille, now called the ''Université de Lille Sciences et Technologies'', and keeps strong links with the Natural History Museum of Lille. Its activities and evolution were closely related to those of the coal-mining basin of the area until the last shaft was closed in 1990. Its activities are both in the fields of applied and fundamental geosciences. From its beginning, the Society has published the results of the research of its members, both in a periodical journal, the Annales, and as monographies called Mémoires. From the 1970s, the Mémoires have been progressively replaced by Publications, mostly devoted to State doctoral theses. During the transition from the 20th to the 21st century, the activities of the Society have strongly declined, due to several internal and external factors. Since the beginning of the 21st century, the SGN has tried to adapt itself to the new conditions of both the university and the regional territory. It is still a scientific society, but it is open to its social environment. (Author) [French] La « Société Géologique du Nord » tiene su sede en Lille, en el norte de Francia. Se fundó en 1870, con Jules Gosselet como primer presidente. Siempre ha estado vinculada al Departamento de Geología de la Facultad de Ciencias de Lille, actualmente Université de Lille – Sciences et Technologies, y mantiene fuertes vínculos con el Museo de Historia Natural de Lille. Sus actividades y su evolución han estado relacionadas con las de la cuenca minera (hullera) de la región, hasta que, en 1990, cerró el último pozo de mina. Sus intereses son, a la vez, en el campo de las geociencias fundamentales y aplicadas. Desde su fundación, la Sociedad ha publicado los

  20. Voyager Interactive Web Interface to EarthScope

    Science.gov (United States)

    Eriksson, S. C.; Meertens, C. M.; Estey, L.; Weingroff, M.; Hamburger, M. W.; Holt, W. E.; Richard, G. A.

    2004-12-01

    Visualization of data is essential in helping scientists and students develop a conceptual understanding of relationships among many complex types of data and keep track of large amounts of information. Developed initially by UNAVCO for study of global-scale geodynamic processes, the Voyager map visualization tools have evolved into interactive, web-based map utilities that can make scientific results accessible to a large number and variety of educators and students as well as the originally targeted scientists. A portal to these map tools can be found at: http://jules.unavco.org. The Voyager tools provide on-line interactive data visualization through pre-determined map regions via a simple HTML/JavaScript interface (for large numbers of students using the tools simultaneously) or through student-selectable areas using a Java interface to a Generic Mapping Tools (GMT) engine. Students can access a variety of maps, satellite images, and geophysical data at a range of spatial scales for the earth and other planets of the solar system. Students can also choose from a variety of base maps (satellite mosaics, global topography, geoid, sea-floor age, strain rate and seismic hazard maps, and others) and can then add a number of geographic and geophysical overlays, for example coastlines, political boundaries, rivers and lakes, earthquake and volcano locations, stress axes, and observed and model plate motion, as well as deformation velocity vectors representing a compilation of over 5000 geodetic measurements from around the world. The related educational website, "Exploring our Dynamic Planet", (http://www.dpc.ucar.edu/VoyagerJr/jvvjrtool.html) incorporates background materials and curricular activities that encourage students to explore Earth processes. One of the present curricular modules is designed for high school students or introductory-level undergraduate non-science majors. The purpose of the module is for students to examine real data to investigate how plate

  1. Polyphony and counterpoint: Mechanisms of seduction in the diaries of Helen Hessel and Henri Pierre Roché

    Directory of Open Access Journals (Sweden)

    Catherine du Toit

    2015-06-01

    Full Text Available Henri Pierre Roché (1879–1959, the author of Jules et Jim, has been called a general introducer, an exemplary amateur, a collector of women and art and one of the most prolific diarists and active lovers in recorded history. Author of a collection of vignettes about Don Juan, Roché was fascinated with the figure of the seducer and in his twenties planned to devote his life to the creation of a body of work which would examine moral, intellectual, social and sexual relations between women and men. To this end, he would transform his life into a laboratory where real-life experiences would become the main source of reference. Roché’s diary spans sixty years and abounds in tales of seduction. However, the most intense and captivating intrigue of seduction and betrayal in his diary, is his relationship with Helen Hessel. At the start of their affair, Roché suggested that she too should keep a diary of the maelstrom of passion into which they were plunged. Written in French, German and English, Helen Hessel’s diary captures the drama of seduction and functions on several levels: realistic, visionary, absorbed in her thoughts and emotions and yet critical of herself and others. A juxtaposed reading of the two diaries generates a fascinatingly dense texture, revealing the mechanisms of seduction at play. The counterpoint created by these two interdependent voices becomes ever more complex as one becomes aware of the intertextual references that contribute to the emerging polyphony of recorded life and love.Polifonie en kontrapunt: Meganismes van verleiding in die dagboeke van Helen Hessel en Henri Pierre Roché. Henri Pierre Roché (1879–1959, outeur van Jules et Jim, word beskryf as ‘n sosiale koppelaar, ‘n model-liefhebber van alles en nog wat, ‘n versamelaar van vroue en kuns en een van die mees produktiewe dagboekskrywers en aktiewe minnaars in die opgetekende geskiedenis. Roché het ‘n reeks sketse oor Don Juan gepubliseer en

  2. La Jolie Fille de Perth de Bizet  ou comment trahir et honorer Walter Scott Bizet’s Jolie Fille de Perth or How to Betray and Honour Walter Scott

    Directory of Open Access Journals (Sweden)

    Gilles Couderc

    2011-11-01

    Full Text Available What remains of Walter Scott’s Fair Maid of Perth in Bizet’s 1867 Jolie Fille de Perth, an opera in 4acts on a libretto by Jules Adenis and Vernoy de Saint-Georges? Not much when compared to other Scott-inspired operas. Little historical context or local colour, even in Bizet’s music. Some characters remotely linked to Scott in a libretto that mostly abides by the rules of French opera or opéra-comique of the time and recycles the dramatic ingredients favoured by Saint-Georges, a purveyor of libretti for opera or the ballet second only to Scribe, who engendered such international successes as Flotow’s Martha and Balfe’s Bohemian Girl, whose gipsy, long before his Carmen, haunts Bizet’s “Scottish” opera. Yet the work pays indirect homage to Scott, whose historical novels contributed to the birth of the French “grand opera”, by rewriting scenes or situations drawn from Scott. In spite of borrowing freely from French grand opera and opéra-comique, Bizet here attempts to find his own musical expression and his opera reflects aspects of Second Empire French society and the roles it assigned to women, before the appearance of his revolutionary Carmen on the stage.Que reste t’il du roman de Walter Scott The Fair Maid of Perth dans la Jolie Fille de Perth de Bizet, opéra en 4 actes de 1867 sur un livret de Vernoy de Saint-Georges, vieux routier du théâtre lyrique, et Jules Adenis ? Pas grand-chose par rapport aux opéras inspirés par Scott. Peu d’Ecosse, une absence remarquable de couleur locale ou historique, des personnages vaguement inspirés de Scott pour un livret qui se plie surtout aux règles de l’opéra français et de l’opéra-comique à la manière de Scribe et recycle les ingrédients habituels des livrets de Saint-Georges, père de succès internationaux comme la Martha de Flotow et de la Bohemian Girl de Balfe, dont la figure exotique de la bohémienne, longtemps avant Carmen, hante l’opéra

  3. Farah Antûn y la recepción activa del pensamiento europeo

    Directory of Open Access Journals (Sweden)

    Josep Puig Montada

    2015-03-01

    Full Text Available Farah Antûn (1874-1922 fue autor teatral y periodista, comprometido social y políticamente en las dos actividades. Su ideal era un estado laico, y en un principio creía que este estado podría comprender los territorios del Imperio Otomano, extendidos desde Estambul hasta El Cairo, pero luego se centró en Egipto, aunque es probable que nunca abandonase el primer objetivo. Difundió sus ideas sobre todo a través de la revista al-GâmiÔa, «La liga». Sus inquietudes sociales influían en cómo debía ser este estado y sus gentes. Farah Antûn leía, traducía e interpretaba escritores europeos. La elección de los escritores refleja sus inquietudes, sea acerca de la bondad y libertad naturales (Bernardin de Saint-Pierre, Jean Jacques Rousseau, de la libertad religiosa, y de conciencia (Lev Tolstoy, o de la educación pública (Jules Simon. La sociedad ideal aceptaría religión en una forma abierta, y se inspiraba en los escritos de Ernest Renan, varios de los cuales tradujo al árabe. Su relación con F. Nietsche fue ambivalente. Farah Antûn rechazaba sus doctrinas morales pero se sentía atraído por su fe en el poder de la voluntad, doctrina que le parecía había llevado a los Estados Unidos de América a su esplendor y que ayudaría a los países árabes a alcanzarlo también. Sin embargo, los valores representados por la tradición liberal francesa resultaban más importantes.

  4. Seasonal variations of soil erosion in UK under climate change: simulations with the use of high-resolution regional climatic models

    Science.gov (United States)

    Ciampalini, Rossano; Kendon, Elizabeth; Constantine, José Antonio; Schindewolf, Marcus; Hall, Ian

    2017-04-01

    Climate change is expected to have a significant impact on the hydrological cycle, twenty-first century climate change simulations for Great Britain forecast an increase of surface runoff and flooding frequency. Once quality and resolution of the simulated rainfall deeply influence the results, we adopted rainfall simulations issued of a high-resolution climate model recently carried out for extended periods (13 years for present-day and future periods 2100) at 1.5 km grid scale over the south of the United Kingdom (simulations, which for the future period use the Intergovernmental Panel on Climate Change RCP 8.5 scenario, Kendon et al., 2014). We simulated soil erosion with 3D soil erosion model Schmidt (1990) on two catchments of Great Britain: the Rother catchment (350 km2) in West Sussex, England, because it has reported some of the most erosive events observed during the last 50 years in the UK, and the Conwy catchment (628 Km2) in North Wales, which is extremely resilient to soil erosion because of the abundant natural vegetation. Estimation of changes in soil moisture, saturation deficit as well as vegetation cover at daily time step have been done with the Joint UK Land Environment Simulator (JULES) (Best et al, 2011). Our results confirm the Rother catchment is the most erosive, while the Conwy catchment is the more resilient to soil erosion. Sediment production is perceived increase in both cases for the end of the century (27% and 50%, respectively). Seasonal disaggregation of the results revels that, while the most part of soil erosion is produced in winter months (DJF), the higher soil erosion variability for future periods is observed in summer (JJA). This behaviour is supported by the rainfall simulation analyse which highlighted this dual behaviour in precipitations.

  5. Evaluation of climate-related carbon turnover processes in global vegetation models for boreal and temperate forests.

    Science.gov (United States)

    Thurner, Martin; Beer, Christian; Ciais, Philippe; Friend, Andrew D; Ito, Akihiko; Kleidon, Axel; Lomas, Mark R; Quegan, Shaun; Rademacher, Tim T; Schaphoff, Sibyll; Tum, Markus; Wiltshire, Andy; Carvalhais, Nuno

    2017-08-01

    Turnover concepts in state-of-the-art global vegetation models (GVMs) account for various processes, but are often highly simplified and may not include an adequate representation of the dominant processes that shape vegetation carbon turnover rates in real forest ecosystems at a large spatial scale. Here, we evaluate vegetation carbon turnover processes in GVMs participating in the Inter-Sectoral Impact Model Intercomparison Project (ISI-MIP, including HYBRID4, JeDi, JULES, LPJml, ORCHIDEE, SDGVM, and VISIT) using estimates of vegetation carbon turnover rate (k) derived from a combination of remote sensing based products of biomass and net primary production (NPP). We find that current model limitations lead to considerable biases in the simulated biomass and in k (severe underestimations by all models except JeDi and VISIT compared to observation-based average k), likely contributing to underestimation of positive feedbacks of the northern forest carbon balance to climate change caused by changes in forest mortality. A need for improved turnover concepts related to frost damage, drought, and insect outbreaks to better reproduce observation-based spatial patterns in k is identified. As direct frost damage effects on mortality are usually not accounted for in these GVMs, simulated relationships between k and winter length in boreal forests are not consistent between different regions and strongly biased compared to the observation-based relationships. Some models show a response of k to drought in temperate forests as a result of impacts of water availability on NPP, growth efficiency or carbon balance dependent mortality as well as soil or litter moisture effects on leaf turnover or fire. However, further direct drought effects such as carbon starvation (only in HYBRID4) or hydraulic failure are usually not taken into account by the investigated GVMs. While they are considered dominant large-scale mortality agents, mortality mechanisms related to insects and

  6. The effect of GCM biases on global runoff simulations of a land surface model

    Science.gov (United States)

    Papadimitriou, Lamprini V.; Koutroulis, Aristeidis G.; Grillakis, Manolis G.; Tsanis, Ioannis K.

    2017-09-01

    Global climate model (GCM) outputs feature systematic biases that render them unsuitable for direct use by impact models, especially for hydrological studies. To deal with this issue, many bias correction techniques have been developed to adjust the modelled variables against observations, focusing mainly on precipitation and temperature. However, most state-of-the-art hydrological models require more forcing variables, in addition to precipitation and temperature, such as radiation, humidity, air pressure, and wind speed. The biases in these additional variables can hinder hydrological simulations, but the effect of the bias of each variable is unexplored. Here we examine the effect of GCM biases on historical runoff simulations for each forcing variable individually, using the JULES land surface model set up at the global scale. Based on the quantified effect, we assess which variables should be included in bias correction procedures. To this end, a partial correction bias assessment experiment is conducted, to test the effect of the biases of six climate variables from a set of three GCMs. The effect of the bias of each climate variable individually is quantified by comparing the changes in simulated runoff that correspond to the bias of each tested variable. A methodology for the classification of the effect of biases in four effect categories (ECs), based on the magnitude and sensitivity of runoff changes, is developed and applied. Our results show that, while globally the largest changes in modelled runoff are caused by precipitation and temperature biases, there are regions where runoff is substantially affected by and/or more sensitive to radiation and humidity. Global maps of bias ECs reveal the regions mostly affected by the bias of each variable. Based on our findings, for global-scale applications, bias correction of radiation and humidity, in addition to that of precipitation and temperature, is advised. Finer spatial-scale information is also provided

  7. Irradiation rigs in material testing reactor

    Energy Technology Data Exchange (ETDEWEB)

    Rozenblum, F.; Gonnier, C.; Bignan, G. [CEA, Research Centers of Saclay and Cadarache (France)

    2011-07-01

    Osiris is a research reactor with a thermal power of 70 MW. It is a light-water reactor, open-core pool type, the principal aim of which is to carry out tests and irradiate structural materials and fuel elements of nuclear power plants under a high flux of neutrons, and to produce radioisotopes. Osiris operates around 200 days a year, in cycles of varying lengths from 3 to 4 weeks. A shutdown of about 10 days between two cycles allows reloading the core with fuel. Mainly 2 types of irradiation device are present: capsules for materials irradiation (CHOUCA and IRMA devices) and fuels irradiation loops (GRIFFONOS and ISABELLE). Although Osiris is still providing experiments of very good quality, it is facing obsolescence due to its ageing. Osiris is planned to be shut down during next decade. Consequently, it has been decided to launch the construction of the Jules Horowitz Reactor (JHR) in Cadarache. JHR is a water cooled reactor which provides the necessary flexibility and accessibility to manage several highly instrumented experiments, reproducing different reactor environments (water, gas or liquid metal loops), generating transient regimes (key for safety). The JHR facility includes the reactor building, including core, cooling system and the experimental bunkers connected to the core through pool wall penetrations and the auxiliary building, including pools and hot cells necessary for the experimental irradiation process. JHR core is optimised to produce high fast neutron flux to study structural material ageing and high thermal neutrons flux for fuel experiments. The conception of this first fleet of devices integrates the operational experience accumulated by the existing MTR and specifically the Osiris one

  8. The Command of Space: A National Vision for American Prosperity and Security

    Science.gov (United States)

    2000-03-01

    This paper develops a compelling case for a national space vision to advance the American vital interests of prosperity and security. The first half of paper focuses on laying the background for the vision that follows in the second half. In the title, prosperity is listed before security since it is the reason for exploration and eventually requires protection. The paper begins with the premise that space is becoming an information center of gravity that is increasingly important to the commercial sector as well as the military. However, a major stumbling block in this transition is the lack of the means to protect on-orbit space systems. Without this capability, true command of space is not possible. The paper then transitions to a discourse on the current dependence on space in America. Next, the quest for wealth and information by the European powers in the second millennium is discussed. Each of these examples demonstrates a recurring cycle in their quest: knowledge, exploitation, investment, consumption and protection. This same cycle is seen in the early days of space where the focus was almost exclusively on knowledge and exploration. Several who possessed a vision to advance space were Jules Verne, Wernher von Braun and Arthur C. Clark. From the early days of space, the transition is made to reviewing a current focus on investment and consumption.To make the case for protecting space assets, the role of the U.S. Navy in protecting maritime commerce is examined as well as the current threat to the space sector.

  9. Study by similarity of wind influence on mass transfers in complex buildings; Etude par similitude de l'influence du vent sur les transferts de masse dans les batiments complexes

    Energy Technology Data Exchange (ETDEWEB)

    Le Roux, Nicolas

    2011-12-05

    Residential and industrial buildings equipped with a ventilation system are complex facilities, where various heat and mass transfers could occur according to the operating conditions. In order to study these mass transfers, a methodology has been developed so as to carry out reduced-scale experiments for the study of isothermal flows, in steady or transient state. This methodology has been numerically and experimentally validated on simple configurations, and then applied to two standard configurations, representing nuclear facilities. The wind influence on mass transfers inside these configurations, in normal, damaged (stopping ventilation) or accidental (internal overpressure) situations, has been studied in the Jules Verne climatic wind tunnel of the CSTB. The wind effects, coupled or not with an internal overpressure, can lead to a partial or a total loss of the pollutant's containment inside buildings. Moreover, the wind turbulence can bring about instantaneous reversal leakage flow-rates, which cannot be identified in steady state. In addition, the study of transient phenomena has highlighted the low influence of the branch inertia on transient flows, for typical values of real facilities. Finally, tracer tests have been carried out in order to study the pollutant dispersion inside a standard configuration subjected to wind, mechanical ventilation and internal overpressure effects. The reliability of the zonal code SYLVIA, used notably to support safety assessment in nuclear buildings, has been analyzed from these experimental results. The modelling of the physical phenomena experimentally observed has been validated, in steady and transient states. However, limitations have been identified for the study of pollutant dispersion, due to hypothesis used in SYLVIA code, as in all zonal codes (homogenous concentration inside rooms, instantaneous propagation inside branches and rooms). (author)

  10. The ADM-AEOLUS Solar Array

    Science.gov (United States)

    Riva, S.; Ferrando, E.; Contini, R.; Blok, R.; Heijden, R. vd; Caon, A.; Labruyere, G.; Strobl, G.; Koestler, W.; Zimmermann, W.

    2008-09-01

    ADM Aeolus is an Earth Explorer Core Mission of the European Space Agency (ESA). The satellite is provided with a deployable solar array fully equipped with European state of the art Triple Junction (TJ) GaAs solar cells.The structural part and mechanisms of the ADM Aeolus Solar Array (SA) is a derivate of the Dutch Space FRED solar array concept. This FRED type solar array has already been used on Jules Verne (Automated Transfer Vehicle) and Giove-A. Both satellites has been successfully launched and the Solar Arrays are working nominally.The ADM Aeolus spacecraft (S/C) is powered by two deployable wings. Each of them composed by three panels and with a panel size of 1.1×2.2 m2, so that the total area is about 14.5 m2;. European TJ solar cells (27% efficiency class) embodying an integral protection diode were selected to meet the power budget, necessary for the installed payload. The principal one is an Atmospheric LAser Doppler INstrument (ALADIN), a novel system whose development is a strategic goal for ESA.This SA program is a challenging development in terms of solar cell qualification because of the extensive characterisation and qualification campaign performed for the cell and the integral diode components. Especially for protection diode a long duration high temperature test was performed in order to simulate and cover all lifetime stresses.Main drivers for PVA design are the power requirement at the end of life and the requested protection against atomic oxygen erosion.This paper describes : The results achieved during the qualification phase, from bare cell level to the coupon level, The design activity, mainly focused on the prediction of EOL performances, The acceptance phase at panel levels, which has verified the suitability of the design assumption and manufacturing workmanship.

  11. Surface vector mapping of magnetic anomalies over the Moon using Kaguya and Lunar Prospector observations

    Science.gov (United States)

    Tsunakawa, Hideo; Takahashi, Futoshi; Shimizu, Hisayoshi; Shibuya, Hidetoshi; Matsushima, Masaki

    2015-06-01

    We have provided preliminary global maps of three components of the lunar magnetic anomaly on the surface applying the surface vector mapping (SVM) method. The data used in the present study consist of about 5 million observations of the lunar magnetic field at 10-45 km altitudes by Kaguya and Lunar Prospector. The lunar magnetic anomalies were mapped at 0.2° equi-distance points on the surface by the SVM method, showing the highest intensity of 718 nT in the Crisium antipodal region. Overall features on the SVM maps indicate that elongating magnetic anomalies are likely to be dominant on the Moon except for the young large basins with the impact demagnetization. Remarkable demagnetization features suggested by previous studies are also recognized at Hertzsprung and Kolorev craters on the farside. These features indicate that demagnetized areas extend to about 1-2 radii of the basins/craters. There are well-isolated central magnetic anomalies at four craters: Leibnitz, Aitken, Jules Verne, and Grimaldi craters. Their magnetic poles through the dipole source approximation suggest occurrence of the polar wander prior to 3.3-3.5 Ga. When compared with high-albedo markings at several magnetic anomalies such as the Reiner Gamma anomalies, three-dimensional structures of the magnetic field on/near the surface are well correlated with high-albedo areas. These results indicate that the global SVM maps are useful for the study of the lunar magnetic anomalies in comparison with various geological and geophysical data.

  12. Optograms and criminology: science, news reporting, and fanciful novels.

    Science.gov (United States)

    Lanska, Douglas J

    2013-01-01

    A persistent nineteenth-century urban legend was the notion that photograph-like images of the last-seen object or person would be preserved in the eyes of the dead. This popular notion followed technological developments (the daguerreotype and ophthalmoscope) that antedated by decades a basic understanding of retinal physiology. From 1876 to 1877, Boll described photochemical bleaching of the retina and produced a crude retinal image that remained briefly visible after death in an experimental animal. From 1877 to 1881, Kühne elaborated the processes involved in photochemical transduction, and created more complex retinal images, or "optograms," that were visible after the death of experimental animals under special laboratory circumstances. In 1880, Kühne reported the first human "optogram" when he examined the eyes following the state execution of a convicted murderer. Although the work of these physiologists increased public interest in "optography" as a potential tool in forensic investigations, Kühne and his student, Ayres, concluded after an extensive series of investigations that optography would never be useful for this purpose. Nevertheless, because of the prior tantalizing results, optography became a frequent consideration in speculative news reports of sensational unsolved murders, and as a plot device in works of fiction, some quite fantastical. Fictional portrayals included works by Rudyard Kipling and Jules Verne. Despite denouncement of optography for forensic investigations by Kühne, and by numerous physicians, the general public and mass media continued to press for examination of the retinae of murder victims well into the twentieth century, particularly in high-profile unsolved cases. © 2013 Elsevier B.V. All rights reserved.

  13. Understanding Green Flashes

    Science.gov (United States)

    Young, Andrew T.

    1998-05-01

    Most astronomers learn about green flashes from either Minnaert's old book (Dover, 1954) or O'Connell's ``The Green Flash....'' Both have defects. Minnaert's account mostly represents what was known in the 1920s; it repeats Mulder's 3-fold classification, which omits Joule's second type of flash --- the one most commonly seen from mountain observatories. O'Connell searched only the astronomical literature, missing Dietze's crucially important paper (Z.f.Met. 9, 169 (1955)) showing that the ``textbook'' mechanism cannot produce flashes visible to the naked eye. He also erred in thinking that distortions of the setting Sun arise in the upper atmosphere (they are due to the marine boundary layer), and copied an error from Feenstra Kuiper's thesis that misidentified a common mirage-like phenomenon as Wegener's ``blank strip'' (Young et al., Appl. Opt. 36, 2689 (1997).) Most phenomena shown in O'Connell's book are caused by inversion layers below eye level, not above as in Wegener's phenomenon. The two commonest forms of green flash are associated with the inferior mirage and the mock mirage, corresponding to Fisher's Type A and Type B sunsets, respectively. Superrefraction, advocated by Wood and by Rayleigh as the cause of large flashes, actually suppress them: the airmass is proportional to the refraction (by Laplace's extinction theorem), so no green is transmitted when refraction is much larger than average. Although there is a physical green flash that can be photographed, the colors seen at sunset are strongly modified by bleaching of the L cones. Most ``green'' sunset flashes are actually yellow. Writers should stop representing Jules Verne's ``ancient legend'' as fact, as it was invented by Verne as a plot device for his novel ``Le Rayon Vert.'' Green-flash photos and simulations will be shown. This material is based upon work supported by the NSF under Award No. ATM-9714357.

  14. Global Aspects of the Exploration of Space

    Science.gov (United States)

    Dryden, Hugh L.

    1959-01-01

    The interest of man in outer space began long ago among uncivilized peoples to whom the face of the sky was clock and almanac; the celestial bodies, objects of worship. Exploration was at first by visual observation, later aided by armillary spheres and quadrants, and still later by more precise measuring instruments, telescopes, and spectroscopes. The information obtained was that borne by the light that was transmitted from the distant celestial object through the atmosphere to the observing instrument on the ground. In recent years the light waves have been supplemented by radio waves as carriers of information from the stars and planets. Men of many nations have contributed through the centuries to the exploration of space by the methods of astronomy. The history of advances in astronomical knowledge and technique includes the records of Chinese, Babylonians, Greeks, Arabians, and of nearly every nation of the modern world. International cooperation was early recognized as essential and beneficial; the countless number of the stars and the vastness of space present mankind with a truly global task. The picture of the universe obtained by the astronomers early stirred the imagination of men to speculate about the existence of life elsewhere in the universe, about means of communication with distant stars, and in the last centuries about the possibility of the travel of man to the moon and planets. Some sought to apply the science and engineering of their day to describe the vehicles to be used. For example, Jules Verne published in 1865 in "From the Earth to the Moon" a description of a gun-launched projectile carrying passengers to orbit the moon. Today we have taken the first steps to bring this inspired vision to reality. The exploration of space by unmanned vehicles carrying scientific apparatus began on October 4, 1957; exploration by man will follow in due course.

  15. Methodology for Developing a Probabilistic Risk Assessment Model of Spacecraft Rendezvous and Dockings

    Science.gov (United States)

    Farnham, Steven J., II; Garza, Joel, Jr.; Castillo, Theresa M.; Lutomski, Michael

    2011-01-01

    In 2007 NASA was preparing to send two new visiting vehicles carrying logistics and propellant to the International Space Station (ISS). These new vehicles were the European Space Agency s (ESA) Automated Transfer Vehicle (ATV), the Jules Verne, and the Japanese Aerospace and Explorations Agency s (JAXA) H-II Transfer Vehicle (HTV). The ISS Program wanted to quantify the increased risk to the ISS from these visiting vehicles. At the time, only the Shuttle, the Soyuz, and the Progress vehicles rendezvoused and docked to the ISS. The increased risk to the ISS was from an increase in vehicle traffic, thereby, increasing the potential catastrophic collision during the rendezvous and the docking or berthing of the spacecraft to the ISS. A universal method of evaluating the risk of rendezvous and docking or berthing was created by the ISS s Risk Team to accommodate the increasing number of rendezvous and docking or berthing operations due to the increasing number of different spacecraft, as well as the future arrival of commercial spacecraft. Before the first docking attempt of ESA's ATV and JAXA's HTV to the ISS, a probabilistic risk model was developed to quantitatively calculate the risk of collision of each spacecraft with the ISS. The 5 rendezvous and docking risk models (Soyuz, Progress, Shuttle, ATV, and HTV) have been used to build and refine the modeling methodology for rendezvous and docking of spacecrafts. This risk modeling methodology will be NASA s basis for evaluating the addition of future ISS visiting spacecrafts hazards, including SpaceX s Dragon, Orbital Science s Cygnus, and NASA s own Orion spacecraft. This paper will describe the methodology used for developing a visiting vehicle risk model.

  16. The genesis of neurosurgery and the evolution of the neurosurgical operative environment: part II--concepts for future development, 2003 and beyond.

    Science.gov (United States)

    Liu, Charles Y; Spicer, Mark; Apuzzo, Michael L J

    2003-01-01

    The future development of the neurosurgical operative environment is driven principally by concurrent development in science and technology. In the new millennium, these developments are taking on a Jules Verne quality, with the ability to construct and manipulate the human organism and its surroundings at the level of atoms and molecules seemingly at hand. Thus, an examination of currents in technology advancement from the neurosurgical perspective can provide insight into the evolution of the neurosurgical operative environment. In the future, the optimal design solution for the operative environment requirements of specialized neurosurgery may take the form of composites of venues that are currently mutually distinct. Advances in microfabrication technology and laser optical manipulators are expanding the scope and role of robotics, with novel opportunities for bionic integration. Assimilation of biosensor technology into the operative environment promises to provide neurosurgeons of the future with a vastly expanded set of physiological data, which will require concurrent simplification and optimization of analysis and presentation schemes to facilitate practical usefulness. Nanotechnology derivatives are shattering the maximum limits of resolution and magnification allowed by conventional microscopes. Furthermore, quantum computing and molecular electronics promise to greatly enhance computational power, allowing the emerging reality of simulation and virtual neurosurgery for rehearsal and training purposes. Progressive minimalism is evident throughout, leading ultimately to a paradigm shift as the nanoscale is approached. At the interface between the old and new technological paradigms, issues related to integration may dictate the ultimate emergence of the products of the new paradigm. Once initiated, however, history suggests that the process of change will proceed rapidly and dramatically, with the ultimate neurosurgical operative environment of the future

  17. Dramatis persona in poetical and practical approach of dramatic text in 17th century French theory of theatre

    Directory of Open Access Journals (Sweden)

    Michał Bajer

    2009-01-01

    Full Text Available The idea of the dramatis persona posited by the first French theatre theorists of the Richelieu circle, Jean Chapelain and Jules de la Mesnardiere, emerges as a quite literał implementation of the Aristotelian concepts unfolded in the sixth and fifteenth chapter of his Poetics. In a later period, the third of the aforementioned group of authors, François Hédelin d’Aubignac, dismisses the Aristotelian categories, erecting his theory upon the elements adopted from the Roman theory of rhetoric. The analysis of the Persona in classical drama theory allows to reconstruct the relation between these two 17th century dramatic approaches. The former is the traditional perspective relying on the postulations of the Aristotelian theory. The latter, which is a practical grasp, is new to the 17th century’s dramatic mindset, and was formulated by abbé d’Aubignac. Whereas the axis of poetics is the structural analysis of a work of art, it is the functioning of that work of art in the theatrical process of communication between the stage and the audience that remains the core interest of the practical approach. In this process, the rhetorical effect of presence of the dramatis persona should by created in the imagination of the spectator-auditor. The subject of analysis is common to both perspectives and the discrepancies concem merely aspects of its description. Therefore poetics and practice are neither competitive nor mutually exclusive, but can both legitimately coexist in the description of the very same work of art.

  18. 业余作家的春天——2011年法国龚古尔文学奖得主亚力克西·热尼

    Institute of Scientific and Technical Information of China (English)

    陈路

    2012-01-01

    2011年11月2日,一年一度的法国文学最高奖——龚古尔文学奖( Prix Goncourt)揭晓,四十八岁的里昂圣马可高中生物老师亚力克西·热尼( Alexis Jenni),凭借其处女作《法国兵法》折桂,成为龚古尔文学奖历史上少有的因处女作获奖的作家.同时,该书也入围了本年度美第奇( Medicis)、勒诺多(Renaudot)和费米娜(Femina)三大文学大奖的提名,成为该年法国文坛轰动性的"大事件".龚古尔文学奖创立于1902年,1903年颁出第一届奖项,是19世纪法国作家爱德蒙·德·龚古尔(Edmond de Goncourt,1822-1896)为纪念他早逝的弟弟儒勒·德·龚古尔(Jules de Goncourt,1830-1870)而设立的奖项.该奖旨在奖励新人新作,授予从当年发表的小说中评选出来的最佳新人作品,是法国最负盛名的文学大奖.龚古尔文学奖评委会共有十位委员,历届评委包括福楼拜( Gustave Flaubert)、左拉(Emile Zola)、都德( Alphonse Daudet)等享誉世界的文坛巨匠.

  19. A plea for commonality: disability history, discourses of rehabilitation, and the individual

    Directory of Open Access Journals (Sweden)

    Pieter Verstraete

    2016-12-01

    Full Text Available Since the late twentieth century, disability history has grown out of its infancy. Scholars from a variety of backgrounds have increasingly become convinced of the value of looking at the past through the lens of disability. Many studies have focused on the constructed nature of disability and thus deliberately tried to deconstruct contemporary distinctions between able-bodied and disabled individuals. By positively revaluing the particular position of the individual with disabilities on the basis of historical narratives, an attempt was made to counter ongoing tendencies of discrimination and oppression. In this article, we would like to remind the reader of another approach which sometimes runs the danger of being snowed under, namely a historical venture that seeks to uncover commonalities: places where the distinctions between persons with and without disabilities are temporarily forgotten and/ or erased, moments when the boundaries between the self and the other are being reconfigured. In order to do so, we will draw on an influential discourse from the history of disability itself: the discourse of rehabilitation. Going back to the early twentieth century, we will present the work of French scientist Jules Mardochée Amar and two Belgian disabled soldiers from the First World War. Amar’s ideas on rehabilitation would prove influential for the actual practices of rehabilitation during and after the war. The two Belgian disabled soldiers were retrained in a professional institute for rehabilitation established by the Belgian government in the north of France. By juxtaposing Amar’s discourse with the experiences of the two Belgian soldiers, we will demonstrate how, besides the discursive individual of rehabilitation, one also can find moments when that individual is absorbed by a real and tangible commonality. As a consequence, everybody —whether able-bodied citizen or mutilated soldier— becomes part of a community of equals.

  20. Nuclear Heating Measurement in Critical Facilities and Experimental Validation of Code and Libraries - An Application to Prompt and Delayed γ Nuclear Data Needs

    Science.gov (United States)

    Blaise, P.; Di Salvo, J.; Vaglio-Gaudard, C.; Bernard, D.; Amharrak, H.; Lemaire, M.; Ravaux, S.

    Energy from prompt and delayed gammas in actual and future nuclear systems are more and more taken into account into design studies as they play an important role in the assessment of performance and safety concerns. Their incomplete knowledge (both prompt and delayed) require to take conservative design margins on local dimensioning parameters, thus reducing the awaited performances or flexibility of these facilities, with costs that are far from being negligible. The local energy photon deposit must be accurately known for Generation-III (Gen-III), Generation-IV (Gen-IV) or the new MTR Jules Horowitz Reactor (JHR). The last 2 decades has seen the realization, in Zero Power Reactors (ZPR), of several programs partially devoted to γ-heating measurements. Experimental programs were and are still conducted in different Cadarache facilities such as MASURCA (for SFR), and later in MINERVE and EOLE (for JHR and Gen-III reactors). The adequacy of the γ-heating calculation was compared to experimental data using thermo-luminescent (TL) detectors and γ-fission chambers. Inconsistencies in C/E and associated uncertainties led to improvement of both libraries and experimental techniques. For these last one, characterization for TL and optically stimulated (OSL) detectors (calibration, individual response), and Monte Carlo calculation of charge repartition in those detectors and their environment were carefully checked and optimized. This step enabled to reduce the associated experimental uncertainty by a factor of 2 (8% at 2σ). Nevertheless, interpretation of integral experiment with updated calculation schemes and improved experimental techniques still tend to prove that there are some nuclei for which there are missing or erroneous data, mainly in structural and absorbing materials. New integral and differential measurements are needed to guide new evaluation efforts, which could benefit from consolidated theoretical and experimental modeling techniques.

  1. SITC 26th annual meeting – summary

    Directory of Open Access Journals (Sweden)

    Romano Emanuela

    2012-05-01

    Full Text Available Abstract The 26th annual meeting of the Society for Immunotherapy of Cancer took place in Bethesda on November 4 to 6, 2011 and was organized by Charles G. Drake (Johns Hopkins University Dolores J. Schendel (Helmholtz Zentrum Muenchen – German Research Center for Environmental Health Institute of Molecular Immunology, Jeffrey Schlom (National Cancer Institute, National Institutes of Health, and Jedd D. Wolchok (Memorial Sloan-Kettering Cancer Center. It was an event marked by a number of extraordinary circumstances: it attracted a record attendance of 805 participants from 24 different countries. The gathering came in the wake of great as well as very sad news for the tumor immunology community. Good news included the approval of anti-CTLA-4 as a therapy for metastatic melanoma in April and the announcement in early October of the Nobel Prize in Physiology and Medicine awarded to pioneering studies in the field of immunology. Indeed, one part of the prize went to Dr. Bruce Beutler, Scripps Research Institute, La Jolla, USA and Dr. Jules Hoffman, Institute for Molecular Cell Biology, Strasbourg, France, for their discoveries in innate immunity and the other part to Dr. Ralph Steinman, The Rockfeller University, New York, for his discovery of dendritic cells. Sad news was the losses of two giants in the field. Jürg Tschopp of the University of Lausanne in March and Ralph Steinman, who passed away just three days before his Nobel Prize announcement. The loss of these two charismatic scientific leaders was particularly sad for the Annual Meeting as both J. Tschopp and R. Steinman were confirmed speakers at this meeting: the former to deliver the keynote lecture and the latter as recipient of the Richard V. Smalley prize.

  2. Evaluation of the uncertainty due to land cover observation and conversion into plant functional types

    Science.gov (United States)

    Georgievski, Goran; Hartley, Andrew; MacBean, Natasha; Hagemann, Stefan

    2016-04-01

    Land surface processes represented in the latest generation of climate models (IPCC AR5) use the concept of Plant Functional Types (PFTs) to group different vegetation types and species according to similar physiological, biochemical and structural characteristics. The 5th IPCC Assessment Report recognizes the role of the Land Surface Models (LSMs) as one of the key contributors to uncertainty in climate change impacts projections. In the frame of the European Space Agency (ESA) Climate Change Initiative (CCI), a new global land cover (LC) data set was derived. We aim to investigate two sources of uncertainties in LSMs and their ranges: (i) uncertainty of ESA-CCI state of the art satellite observation of LC classes, and (ii) uncertainty due to LC conversion ("cross-walking (CW) procedure") into PFTs. Therefore, we have derived 5 perturbations of PFTs maps: (i) reference map (REF), (ii) map that minimizes biomass in LC observation and CW procedure (MinLC MinCW), (iii) map that minimizes biomass in LC observation with reference CW procedure (MinLC RefCW), (iv) map that maximizes biomass in LC observation with reference CW procedure (MaxLC RefCW), and (v) map that maximizes biomass in LC observation and CW procedure (MaxLC MaxCW). Our analysis demonstrates that there is still considerable uncertainty in the methods used to convert LC classes into the PFTs used by LSMs. Furthermore, uncertainty in the labelling of LC classes has an equal magnitude compared to the cross-walking uncertainty. In the next phase, we aim to quantify the sensitivity of the carbon, hydrological and energy cycles to LC and CW uncertainty with 3 LSMs (JSBACH, JULES, and ORHCIDEE). This work will enable us to both advice the land cover mapping community about the accuracy requirements for land cover maps, and to provide insights to the earth system modelling community on the implications of decisions taken when converting from land cover classes to PFTs.

  3. The Representation of the Australian Aborigines in Text and Picture: Dr. Med. Pál Almási Balogh (1794-1863 and the Birth of the Science of Anthropology in Central Europe/Hungary

    Directory of Open Access Journals (Sweden)

    Ildiko Sz. Kristof

    2014-11-01

    Full Text Available The article discusses a manuscript entitled Az ember Australiában (The Man in Australia found in one of the collections of private files in the University Library of Eötvös Loránd University, Budapest. Preserved in the miscellaneous files of Pál Almási Balogh, a Hungarian physician active mostly during the first half of the 19th century, and written in Hungarian, this writing describes the bodily structure, the way of life and the geographical environment of the Australian aborigines. Written probably around 1835 and divided into chapters like “Religion”, “Habitation”, “Way of life”, “Marriage”, “Superstition”, “Inclinations”, “Dress”, and “Language,” the manuscript seems however never to have been published. The author identifies this writing of Almási Balogh as the first scientific, ethnographical/anthropological monograph ever written in Hungary on the native inhabitants of the fifth continent, and she analyzes its content according to both its textual-philological and visual-figural register. According to her results, the manuscript was compiled from the works of Jules Dumont d’Urville (1790-1842, David Collins (1756-1810, George Barrington (1755-1804, Alan Cunningham (1791-1839, James Cook (1728-1779, and perhaps some other Western European explorers and natural historians of Australia. And, as for its visual register, it relied heavily on the illustrations of Voyage pittoresque autour du monde of Dumont d’Urville, published in different languages in Western Europe from 1834-1835 on.

  4. Assessment of model behavior and acceptable forcing data uncertainty in the context of land surface soil moisture estimation

    Science.gov (United States)

    Dumedah, Gift; Walker, Jeffrey P.

    2017-03-01

    The sources of uncertainty in land surface models are numerous and varied, from inaccuracies in forcing data to uncertainties in model structure and parameterizations. Majority of these uncertainties are strongly tied to the overall makeup of the model, but the input forcing data set is independent with its accuracy usually defined by the monitoring or the observation system. The impact of input forcing data on model estimation accuracy has been collectively acknowledged to be significant, yet its quantification and the level of uncertainty that is acceptable in the context of the land surface model to obtain a competitive estimation remain mostly unknown. A better understanding is needed about how models respond to input forcing data and what changes in these forcing variables can be accommodated without deteriorating optimal estimation of the model. As a result, this study determines the level of forcing data uncertainty that is acceptable in the Joint UK Land Environment Simulator (JULES) to competitively estimate soil moisture in the Yanco area in south eastern Australia. The study employs hydro genomic mapping to examine the temporal evolution of model decision variables from an archive of values obtained from soil moisture data assimilation. The data assimilation (DA) was undertaken using the advanced Evolutionary Data Assimilation. Our findings show that the input forcing data have significant impact on model output, 35% in root mean square error (RMSE) for 5cm depth of soil moisture and 15% in RMSE for 15cm depth of soil moisture. This specific quantification is crucial to illustrate the significance of input forcing data spread. The acceptable uncertainty determined based on dominant pathway has been validated and shown to be reliable for all forcing variables, so as to provide optimal soil moisture. These findings are crucial for DA in order to account for uncertainties that are meaningful from the model standpoint. Moreover, our results point to a proper

  5. Quantifying the impact of land use change on hydrological responses in the Upper Ganga Basin, India

    Science.gov (United States)

    Tsarouchi, Georgia-Marina; Mijic, Ana; Moulds, Simon; Chawla, Ila; Mujumdar, Pradeep; Buytaert, Wouter

    2013-04-01

    Quantifying how changes in land use affect the hydrological response at the river basin scale is a challenge in hydrological science and especially in the tropics where many regions are considered data sparse. Earlier work by the authors developed and used high-resolution, reconstructed land cover maps for northern India, based on satellite imagery and historic land-use maps for the years 1984, 1998 and 2010. Large-scale land use changes and their effects on landscape patterns can impact water supply in a watershed by altering hydrological processes such as evaporation, infiltration, surface runoff, groundwater discharge and stream flow. Three land use scenarios were tested to explore the sensitivity of the catchment's response to land use changes: (a) historic land use of 1984 with integrated evolution to 2010; (b) land use of 2010 remaining stable; and (c) hypothetical future projection of land use for 2030. The future scenario was produced with Markov chain analysis and generation of transition probability matrices, indicating transition potentials from one land use class to another. The study used socio-economic (population density), geographic (distances to roads and rivers, and location of protected areas) and biophysical drivers (suitability of soil for agricultural production, slope, aspect, and elevation). The distributed version of the land surface model JULES was integrated at a resolution of 0.01° for the years 1984 to 2030. Based on a sensitivity analysis, the most sensitive parameters were identified. Then, the model was calibrated against measured daily stream flow data. The impact of land use changes was investigated by calculating annual variations in hydrological components, differences in annual stream flow and surface runoff during the simulation period. The land use changes correspond to significant differences on the long-term hydrologic fluxes for each scenario. Once analysed from a future water resources perspective, the results will be

  6. Professor Ludwik Rydygier father and legend of Polish surgery.

    Science.gov (United States)

    Bielecki, K

    2011-02-01

    Ludwik Rydygier is undoubtedly the father of Polish gastrointestinal surgery. He performed two pioneering stomach operations: on 16 November 1880, first in Poland and second in the world after Jules Pean, the surgical removal of the pylorus in a 64-year-old patient suffering from stomach cancer; the operation took about four hours, unfortunately the patient died 12 hours later, and on 21 November 1881 he performed the world's first pylorectomy due to gastric ulcer, applying his own method of pylorectomy followed by the restoration by end-to-end anastomosis of the duodenal stump with the stomach stump; the patient survived the operation and recovered. Three years later, Rydygier introduced a new method of surgical treatment of peptic ulcer disease by means of gastroenterostomy. This review was designed to commemorate the outstanding achievements of Professor Rydygier, who worked at two universities: at the Jagiellonian University in Cracow, and at the Lemberg (Lviv) University. He was one of the founders of the Association of Polish Surgeons and an organizer of the first Meeting of Polish Surgeons in 1889. He was the author of over 200 published papers and several text-books on surgical infections, surgical techniques, orthopaedics and traumatology, urology, neurosurgery, and gynaecology. Professor Ludwik Rydygier possessed comprehensive knowledge of surgery and other medical disciplines, he was a courageous surgeon and skilled operator, being at the same time an extremely gifted organizer. His promotion to the rank of General of Polish Army crowned his credits for country's defence. At the anniversary of 90 years after his death, Polish surgeons pay the tribute to their mentor.

  7. Integrating 3D geological information with a national physically-based hydrological modelling system

    Science.gov (United States)

    Lewis, Elizabeth; Parkin, Geoff; Kessler, Holger; Whiteman, Mark

    2016-04-01

    Robust numerical models are an essential tool for informing flood and water management and policy around the world. Physically-based hydrological models have traditionally not been used for such applications due to prohibitively large data, time and computational resource requirements. Given recent advances in computing power and data availability, a robust, physically-based hydrological modelling system for Great Britain using the SHETRAN model and national datasets has been created. Such a model has several advantages over less complex systems. Firstly, compared with conceptual models, a national physically-based model is more readily applicable to ungauged catchments, in which hydrological predictions are also required. Secondly, the results of a physically-based system may be more robust under changing conditions such as climate and land cover, as physical processes and relationships are explicitly accounted for. Finally, a fully integrated surface and subsurface model such as SHETRAN offers a wider range of applications compared with simpler schemes, such as assessments of groundwater resources, sediment and nutrient transport and flooding from multiple sources. As such, SHETRAN provides a robust means of simulating numerous terrestrial system processes which will add physical realism when coupled to the JULES land surface model. 306 catchments spanning Great Britain have been modelled using this system. The standard configuration of this system performs satisfactorily (NSE > 0.5) for 72% of catchments and well (NSE > 0.7) for 48%. Many of the remaining 28% of catchments that performed relatively poorly (NSE information into SHETRAN for any model setup. The addition of more realistic subsurface representation following this approach is shown to greatly improve model performance in areas dominated by groundwater processes. The resulting modelling system has great potential to be used as a resource at national, regional and local scales in an array of different

  8. DART: A Community Facility Providing State-of-the-Art, Efficient Ensemble Data Assimilation for Large (Coupled) Geophysical Models

    Science.gov (United States)

    Hoar, T. J.; Anderson, J. L.; Collins, N.; Kershaw, H.; Hendricks, J.; Raeder, K.; Mizzi, A. P.; Barré, J.; Gaubert, B.; Madaus, L. E.; Aydogdu, A.; Raeder, J.; Arango, H.; Moore, A. M.; Edwards, C. A.; Curchitser, E. N.; Escudier, R.; Dussin, R.; Bitz, C. M.; Zhang, Y. F.; Shrestha, P.; Rosolem, R.; Rahman, M.

    2016-12-01

    Strongly-coupled ensemble data assimilation with multiple high-resolution model components requires massive state vectors which need to be efficiently stored and accessed throughout the assimilation process. Supercomputer architectures are tending towards increasing the number of cores per node but have the same or less memory per node. Recent advances in the Data Assimilation Research Testbed (DART), a freely-available community ensemble data assimilation facility that works with dozens of large geophysical models, have addressed the need to run with a smaller memory footprint on a higher node count by utilizing MPI-2 one-sided communication to do non-blocking asynchronous access of distributed data. DART runs efficiently on many computational platforms ranging from laptops through thousands of cores on the newest supercomputers. Benefits of the new DART implementation will be shown. In addition, overviews of the most recently supported models will be presented: CAM-CHEM, WRF-CHEM, CM1, OpenGGCM, FESOM, ROMS, CICE5, TerrSysMP (COSMO, CLM, ParFlow), JULES, and CABLE. DART provides a comprehensive suite of software, documentation, and tutorials that can be used for ensemble data assimilation research, operations, and education. Scientists and software engineers at NCAR are available to support DART users who want to use existing DART products or develop their own applications. Current DART users range from university professors teaching data assimilation, to individual graduate students working with simple models, through national laboratories and state agencies doing operational prediction with large state-of-the-art models.

  9. DNA methylation-based immune response signature improves patient diagnosis in multiple cancers.

    Science.gov (United States)

    Jeschke, Jana; Bizet, Martin; Desmedt, Christine; Calonne, Emilie; Dedeurwaerder, Sarah; Garaud, Soizic; Koch, Alexander; Larsimont, Denis; Salgado, Roberto; Van den Eynden, Gert; Willard Gallo, Karen; Bontempi, Gianluca; Defrance, Matthieu; Sotiriou, Christos; Fuks, François

    2017-08-01

    The tumor immune response is increasingly associated with better clinical outcomes in breast and other cancers. However, the evaluation of tumor-infiltrating lymphocytes (TILs) relies on histopathological measurements with limited accuracy and reproducibility. Here, we profiled DNA methylation markers to identify a methylation of TIL (MeTIL) signature that recapitulates TIL evaluations and their prognostic value for long-term outcomes in breast cancer (BC). MeTIL signature scores were correlated with clinical endpoints reflecting overall or disease-free survival and a pathologic complete response to preoperative anthracycline therapy in 3 BC cohorts from the Jules Bordet Institute in Brussels and in other cancer types from The Cancer Genome Atlas. The MeTIL signature measured TIL distributions in a sensitive manner and predicted survival and response to chemotherapy in BC better than did histopathological assessment of TILs or gene expression-based immune markers, respectively. The MeTIL signature also improved the prediction of survival in other malignancies, including melanoma and lung cancer. Furthermore, the MeTIL signature predicted differences in survival for malignancies in which TILs were not known to have a prognostic value. Finally, we showed that MeTIL markers can be determined by bisulfite pyrosequencing of small amounts of DNA from formalin-fixed, paraffin-embedded tumor tissue, supporting clinical applications for this methodology. This study highlights the power of DNA methylation to evaluate tumor immune responses and the potential of this approach to improve the diagnosis and treatment of breast and other cancers. This work was funded by the Fonds National de la Recherche Scientifique (FNRS) and Télévie, the INNOVIRIS Brussels Region BRUBREAST Project, the IUAP P7/03 program, the Belgian "Foundation against Cancer," the Breast Cancer Research Foundation (BCRF), and the Fonds Gaston Ithier.

  10. Modelling climate change responses in tropical forests: similar productivity estimates across five models, but different mechanisms and responses

    Directory of Open Access Journals (Sweden)

    L. Rowland

    2014-11-01

    Full Text Available Accurately predicting the response of Amazonia to climate change is important for predicting changes across the globe. However, changes in multiple climatic factors simultaneously may result in complex non-linear responses, which are difficult to predict using vegetation models. Using leaf and canopy scale observations, this study evaluated the capability of five vegetation models (CLM3.5, ED2, JULES, SiB3, and SPA to simulate the responses of canopy and leaf scale productivity to changes in temperature and drought in an Amazonian forest. The models did not agree as to whether gross primary productivity (GPP was more sensitive to changes in temperature or precipitation. There was greater model–data consistency in the response of net ecosystem exchange to changes in temperature, than in the response to temperature of leaf area index (LAI, net photosynthesis (An and stomatal conductance (gs. Modelled canopy scale fluxes are calculated by scaling leaf scale fluxes to LAI, and therefore in this study similarities in modelled ecosystem scale responses to drought and temperature were the result of inconsistent leaf scale and LAI responses among models. Across the models, the response of An to temperature was more closely linked to stomatal behaviour than biochemical processes. Consequently all the models predicted that GPP would be higher if tropical forests were 5 °C colder, closer to the model optima for gs. There was however no model consistency in the response of the An–gs relationship when temperature changes and drought were introduced simultaneously. The inconsistencies in the An–gs relationships amongst models were caused by to non-linear model responses induced by simultaneous drought and temperature change. To improve the reliability of simulations of the response of Amazonian rainforest to climate change the mechanistic underpinnings of vegetation models need more complete validation to improve accuracy and consistency in the scaling

  11. Chapter 40: history of neurology in France.

    Science.gov (United States)

    Clarac, François; Boller, François

    2010-01-01

    The history of neurology in France is characterized by the very high degree of centralization in that country where "everything seems to happen in Paris," and yet the considerable degree of autonomous diversity in the evolution of some other medical schools such as Montpellier and Strasbourg. It could be argued that France saw the birth of clinical neurology as a separate discipline since Jean Martin Charcot at the Salpêtrière Hospital obtained a chair of diseases of the nervous system in 1892, a first in the history of the academic world. The chapter shows, however, that the work of Charcot was preceded by a long evolution in medical thinking, which culminated with the introduction of experimental medicine developed by Claude Bernard and François Magendie, and by the study of aphasia by Paul Broca and its localization of language in a specific area of the brain. Many of the great neurologists of France like Duchenne de Boulogne, Gilles de la Tourette, Joseph Babinski and Pierre Marie gravitated around Charcot while others like Charles-Edward Brown-Sequard and Jules Dejerine developed their talents independently. The history of Sainte-Anne Hospital further illustrates this independence. It also shows the relation between neurology and psychiatry with Henri Ey, Jean Delay and Pierre Deniker, who collaborated with Henri Laborit in the clinical development of chlorpromazine. Sainte Anne also saw the birth of modern neuropsychology with Henry Hécaen. Jean Talairach and his group developed human stereotaxic neurosurgery and a 3-dimensional brain atlas that is used around the world. The chapter also mentions institutions (the CNRS and INSERM) that have contributed to developments partially independently from medical schools. It concludes with a presentation of schools located outside of Paris that have played a significant role in the development of neurology. Six of the most important ones are described: Montpellier, Toulouse, Bordeaux, Strasbourg, Lyon, and

  12. Reducing measurement scale mismatch to improve surface energy flux estimation

    Science.gov (United States)

    Iwema, Joost; Rosolem, Rafael; Rahman, Mostaquimur; Blyth, Eleanor; Wagener, Thorsten

    2016-04-01

    Soil moisture importantly controls land surface processes such as energy and water partitioning. A good understanding of these controls is needed especially when recognizing the challenges in providing accurate hyper-resolution hydrometeorological simulations at sub-kilometre scales. Soil moisture controlling factors can, however, differ at distinct scales. In addition, some parameters in land surface models are still often prescribed based on observations obtained at another scale not necessarily employed by such models (e.g., soil properties obtained from lab samples used in regional simulations). To minimize such effects, parameters can be constrained with local data from Eddy-Covariance (EC) towers (i.e., latent and sensible heat fluxes) and Point Scale (PS) soil moisture observations (e.g., TDR). However, measurement scales represented by EC and PS still differ substantially. Here we use the fact that Cosmic-Ray Neutron Sensors (CRNS) estimate soil moisture at horizontal footprint similar to that of EC fluxes to help answer the following question: Does reduced observation scale mismatch yield better soil moisture - surface fluxes representation in land surface models? To answer this question we analysed soil moisture and surface fluxes measurements from twelve COSMOS-Ameriflux sites in the USA characterized by distinct climate, soils and vegetation types. We calibrated model parameters of the Joint UK Land Environment Simulator (JULES) against PS and CRNS soil moisture data, respectively. We analysed the improvement in soil moisture estimation compared to uncalibrated model simulations and then evaluated the degree of improvement in surface fluxes before and after calibration experiments. Preliminary results suggest that a more accurate representation of soil moisture dynamics is achieved when calibrating against observed soil moisture and further improvement obtained with CRNS relative to PS. However, our results also suggest that a more accurate

  13. Confronting model predictions of carbon fluxes with measurements of Amazon forests subjected to experimental drought.

    Science.gov (United States)

    Powell, Thomas L; Galbraith, David R; Christoffersen, Bradley O; Harper, Anna; Imbuzeiro, Hewlley M A; Rowland, Lucy; Almeida, Samuel; Brando, Paulo M; da Costa, Antonio Carlos Lola; Costa, Marcos Heil; Levine, Naomi M; Malhi, Yadvinder; Saleska, Scott R; Sotta, Eleneide; Williams, Mathew; Meir, Patrick; Moorcroft, Paul R

    2013-10-01

    Considerable uncertainty surrounds the fate of Amazon rainforests in response to climate change. Here, carbon (C) flux predictions of five terrestrial biosphere models (Community Land Model version 3.5 (CLM3.5), Ecosystem Demography model version 2.1 (ED2), Integrated BIosphere Simulator version 2.6.4 (IBIS), Joint UK Land Environment Simulator version 2.1 (JULES) and Simple Biosphere model version 3 (SiB3)) and a hydrodynamic terrestrial ecosystem model (the Soil-Plant-Atmosphere (SPA) model) were evaluated against measurements from two large-scale Amazon drought experiments. Model predictions agreed with the observed C fluxes in the control plots of both experiments, but poorly replicated the responses to the drought treatments. Most notably, with the exception of ED2, the models predicted negligible reductions in aboveground biomass in response to the drought treatments, which was in contrast to an observed c. 20% reduction at both sites. For ED2, the timing of the decline in aboveground biomass was accurate, but the magnitude was too high for one site and too low for the other. Three key findings indicate critical areas for future research and model development. First, the models predicted declines in autotrophic respiration under prolonged drought in contrast to measured increases at one of the sites. Secondly, models lacking a phenological response to drought introduced bias in the sensitivity of canopy productivity and respiration to drought. Thirdly, the phenomenological water-stress functions used by the terrestrial biosphere models to represent the effects of soil moisture on stomatal conductance yielded unrealistic diurnal and seasonal responses to drought.

  14. The ambiguity of drought events, a bottleneck for Amazon forest drought response modelling

    Science.gov (United States)

    De Deurwaerder, Hannes; Verbeeck, Hans; Baker, Timothy; Christoffersen, Bradley; Ciais, Philippe; Galbraith, David; Guimberteau, Matthieu; Kruijt, Bart; Langerwisch, Fanny; Meir, Patrick; Rammig, Anja; Thonicke, Kirsten; Von Randow, Celso; Zhang, Ke

    2016-04-01

    Considering the important role of the Amazon forest in the global water and carbon cycle, the prognosis of altered hydrological patterns resulting from climate change provides strong incentive for apprehending the direct implications of drought on the vegetation of this ecosystem. Dynamic global vegetation models have the potential of providing a useful tool to study drought impacts on various spatial and temporal scales. This however assumes the models being able to properly represent drought impact mechanisms. But how well do the models succeed in meeting this assumption? Within this study meteorological driver data and model output data of 4 different DGVMs, i.e. ORCHIDEE, JULES, INLAND and LPGmL, are studied. Using the palmer drought severity index (PDSI) and the mean cumulative water deficit (MWD), temporal and spatial representation of drought events are studied in the driver data and are referenced to historical extreme drought events in the Amazon. Subsequently, within the resulting temporal and spatial frame, we studied the drought impact on the above ground biomass (AGB) and gross primary production (GPP) fluxes. Flux tower data, field inventory data and the JUNG data-driven GPP product for the Amazon region are used for validation. Our findings not only suggest that the current state of the studied DGVMs is inadequate in representing Amazon droughts in general, but also highlights strong inter-model differences in drought responses. Using scatterplot-studies and input-output correlations, we provide insight in the origin of these encountered inter-model differences. In addition, we present directives of model development and improvement in scope of Amazon forest drought response modelling.

  15. Long-term change in surface air temperature over Eurasian continent and possible contribution from land-surface conditions.

    Science.gov (United States)

    Kim, K.; Jeong, J. H.; Shim, T.

    2015-12-01

    Summertime heat wave over Eurasia is induced by various climatic factors. As internal and external factors are changing under an abrupt climate change, the variability of heat waves exhibits radical changes. In this study, the long-term change in heat wave characteristics over Eurasia for the last several decades was examined and the impact of land-atmosphere interaction modulated by soil moisture variability on the change was investigated. Through the empirical orthogonal functions(EOF) analysis, the principle spatio-temporal pattern of Eurasian heat wave during July-August was objectively detected. The leading pattern (1st EOF mode) of the variability was found be an overall increase in heat waves over eastern Europe and east Asia (Mongol to northern part of China), which seems to be associated mainly with the global warming signal but with interannual variability as well. Through performing JULES(Joint UK Land Environment Simulator) land surface model simulation forced with observational atmospheric forcings, soil moisture and energy flux at surface were estimated, and the impacts of land-atmosphere interaction on the heat wave variability was investigated based on the estimated land surface variables and temperature observations. It is found that there is a distinct dry soil condition accompanying with East Asian heat waves. The dry condition leads to an increase in sensible heat flux from land surface to atmosphere and resulting near-surface warming, which is followed by warm-core high - a typical characteristics of a heatwave sustained by land-atmosphere interaction. This result is consistent with an distinct increase in heatwave in recent years. By using the hindcast of long-range prediction model of KMA, GloSea5, the seasonal predictability of heatwave was examined. GloSea5 reasonably well simulates the spatial pattern of Eurasian heatwaves variability found in observations but shows modest skill in simulating accurate year-to-year variability. This result

  16. How much rainfall sustained a Green Sahara during the mid-Holocene?

    Science.gov (United States)

    Hopcroft, Peter; Valdes, Paul; Harper, Anna

    2016-04-01

    The present-day Sahara desert has periodically transformed to an area of lakes and vegetation during the Quaternary in response to orbitally-induced changes in the monsoon circulation. Coupled atmosphere-ocean general circulation model simulations of the mid-Holocene generally underestimate the required monsoon shift, casting doubt on the fidelity of these models. However, the climatic regime that characterised this period remains unclear. To address this, we applied an ensemble of dynamic vegetation model simulations using two different models: JULES (Joint UK Land Environment Simulator) a comprehensive land surface model, and LPJ (Lund-Potsdam-Jena model) a widely used dynamic vegetation model. The simulations are forced with a number of idealized climate scenarios, in which an observational climatology is progressively altered with imposed anomalies of precipitation and other related variables, including cloud cover and humidity. The applied anomalies are based on an ensemble of general circulation model simulations, and include seasonal variations but are spatially uniform across the region. When perturbing precipitation alone, a significant increase of at least 700mm/year is required to produce model simulations with non-negligible vegetation coverage in the Sahara region. Changes in related variables including cloud cover, surface radiation fluxes and humidity are found to be important in the models, as they modify the water balance and so affect plant growth. Including anomalies in all of these variables together reduces the precipitation change required for a Green Sahara compared to the case of increasing precipitation alone. We assess whether the precipitation changes implied by these vegetation model simulations are consistent with reconstructions for the mid-Holocene from pollen samples. Further, Earth System models predict precipitation increases that are significantly smaller than that inferred from these vegetation model simulations. Understanding

  17. The quality of life impact of peripheral versus central vision loss with a focus on glaucoma versus age-related macular degeneration

    Directory of Open Access Journals (Sweden)

    Keith Evans

    2009-07-01

    Full Text Available Keith Evans1, Simon K Law2, John Walt3, Patricia Buchholz4, Jan Hansen31Global Health Outcomes, Wolters Kluwer Health, Chester, United Kingdom; 2Jules Stein Eye Institute, Los Angeles, CA, USA; 3Global Health Outcomes Strategy and Research, Allergan Inc., Irvine, CA, USA; 4Health Economics, Pricing, and Reimbursement, Allergan GmbH, Ettlingen, GermanyPurpose: It is well accepted that conditions that cause central vision loss (CVL have a negative impact on functional ability and quality of life (QoL, but the impact of diseases that cause peripheral vision loss (PVL is less well understood. Focusing on glaucoma and age-related macular degeneration (ARMD, the effects of CVL and PVL on QoL were compared. Methods: A systematic literature review of publications reporting QoL in patients with CVL or PVL identified 87 publications using four generic (Short-Form Health Survey-36 and -12, EuroQoL EQ-5D and Sickness Impact Profile and five vision-specific (National Eye Institute Visual Function Questionnaire-51, -39, and -25, Impact of Vision Impairment and Visual Function-14 QoL instruments; 33 and 15 publications reported QoL in ARMD and glaucoma, respectively.Results: QoL was impaired to a similar extent by diseases associated with PVL and CVL, but different domains were affected. In contrast to ARMD, mental aspects appeared to be affected more than physical aspects in patients with glaucoma.Conclusions: The differential impact upon QoL might be a function of the pathology of the diseases, for example potential for blindness and better ability to perform physical tasks due to retention of central vision may explain these observations in glaucoma.Keywords: vision loss, quality of life, glaucoma, age-related macular degeneration, diabetic macular edema, cataracts

  18. United States Human Access to Space, Exploration of the Moon and Preparation for Mars Exploration

    Science.gov (United States)

    Rhatigan, Jennifer L.

    2009-01-01

    In the past, men like Leonardo da Vinci and Jules Verne imagined the future and envisioned fantastic inventions such as winged flying machines, submarines, and parachutes, and posited human adventures like transoceanic flight and journeys to the Moon. Today, many of their ideas are reality and form the basis for our modern world. While individual visionaries like da Vinci and Verne are remembered for the accuracy of their predictions, today entire nations are involved in the process of envisioning and defining the future development of mankind, both on and beyond the Earth itself. Recently, Russian, European, and Chinese teams have all announced plans for developing their own next generation human space vehicles. The Chinese have announced their intention to conduct human lunar exploration, and have flown three crewed space missions since 2003, including a flight with three crew members to test their extravehicular (spacewalking) capabilities in September 2008. Very soon, the prestige, economic development, scientific discovery, and strategic security advantage historically associated with leadership in space exploration and exploitation may no longer be the undisputed province of the United States. Much like the sponsors of the seafaring explorers of da Vinci's age, we are motivated by the opportunity to obtain new knowledge and new resources for the growth and development of our own civilization. NASA's new Constellation Program, established in 2005, is tasked with maintaining the United States leadership in space, exploring the Moon, creating a sustained human lunar presence, and eventually extending human operations to Mars and beyond. Through 2008, the Constellation Program developed a full set of detailed program requirements and is now completing the preliminary design phase for the new Orion Crew Exploration Vehicle (CEV), the Ares I Crew Launch Vehicle, and the associated infrastructure necessary for humans to explore the Moon. Component testing is well

  19. Une « culture de guerre universitaire » ? L’expérience des professeurs de l’enseignement secondaire français mobilisés dans la Grande Guerre

    Directory of Open Access Journals (Sweden)

    Matthieu Devigne

    2011-05-01

    Full Text Available Cette contribution se propose d’étudier la culture de guerre dans la France de la Première Guerre mondiale en isolant un groupe de combattants d’après sa profession civile et sa culture universitaire. Cette approche à une échelle intermédiaire conduit à des observations plus générales que l’analyse d’œuvres de la littérature de tranchée, mais plus spécifiques que la prise en compte d’un large contingent d’officiers. Elle permet d’observer de quelles manières les mots d’ordre et les impératifs de la guerre, tels que tuer ou êtres tués, sont compris et assumés par les combattants, qui s’en servent d’instruments performatifs pour forger leurs raisons de « tenir ». Étudier la « culture de guerre » consiste ici à discerner les relations complexes entre l’expérience du feu et la culture civile des soldats. Pour être plus précis, ce travail explique comment le modeste contingent des professeurs de l’enseignement secondaire (un peu plus de 500 hommes, parmi lesquels Marc Bloch, Jules Isaac, Charles Delvert, et d’autres anciens élèves de l’École Normale Supérieure ont employé leurs aptitudes intellectuelles et leurs références culturelles pour faire face au conflit, en acceptant et en rejetant tout autant les principes.This contribution aims to study War Culture in First World War France on the basis of a group of soldiers selected according to their civil profession and common academic background. This medium-scale approach leads to more general observations than the analysis of trench literature would, but it is more accurate than studying a large group of officers. This approach also makes it possible for me to explore how war orders and imperatives, such as killing or being killed, are understood and embraced by soldiers, who use them as performative tools contributing to build up their own reasons to “hold out”. Studying “War culture” thus means making sense of the complex

  20. Obituary: Edward W. Burke, Jr. (1924-2011)

    Science.gov (United States)

    Bloomer, Raymond, Jr.

    2011-12-01

    program there and upon a return visit in 2003 he found that the university physics program was thriving. In the 52 years of his association with King College, Dr. Burke served in many capacities. Over the years he was the tennis coach, Vice President for Academic Affairs, and Chairman of the Division of Natural Sciences and Mathematics for 31 years until his retirement in 1991. He continued to be involved on campus as a Professor Emeritus until his death. Throughout his career he engaged the public in the wonder of astronomy. He organized the Bristol Astronomy Club for the amateur astronomers in the region. In 1957 he spearheaded the King College Moonwatch program, an international man-made satellite observing program organized by the Smithsonian Astronomical Observatory. He initiated Science Open House at King College, a program which hosted hundreds of talented high school junior and senior students from the Appalachian region, to enjoy tours and demonstrations in the science departments. Throughout his career he opened the Burke Observatory for thousands of interested viewers. Burke was a southern gentleman, true to his roots in Macon, Georgia. At the same time he was also a man who never took "no" for an answer. He always found a way to recommend a way to solve a problem, to get a grant to do research, or to plan another observing trip. He was an eternal optimist who seemed to envision the possibilities rather than the limitations. In addition to his duties at King College, he was a long-time member of the Lions Club where he spent considerable time helping disadvantaged people obtain suitable eyeglasses. He also taught Sunday School at State Street United Methodist Church for many years. He was an avid birdwatcher with the Bristol Bird Club. In his later years he competed in badminton at the Senior Olympics and served as a line judge at the 1996 National Senior Olympics in Atlanta. He was married to Julee Struby Burke for 64 years. Julee was a participant in several

  1. The International Space Station and the Space Debris Environment: 10 Years On

    Science.gov (United States)

    Johnson, Nicholas; Klinkrad, Heiner

    2009-01-01

    tracked and cataloged have also been generated, but normally with even shorter orbital lifetimes. Finally, eight collision avoidance maneuvers have been performed to avoid potential collisions between ISS and large, tracked space debris. The most recent such maneuver was accomplished by ESA's Automated Transfer Vehicle, the Jules Verne, just three months before the 10th anniversary of the launch of ISS's first element.

  2. EarthScope Plate Boundary Observatory Data in the College Classroom (Invited)

    Science.gov (United States)

    Eriksson, S. C.; Olds, S. E.

    2009-12-01

    The Plate Boundary Observatory (PBO) is the geodetic component of the EarthScope project, designed to study the 3-D strain field across the active boundary zone between the Pacific and North American tectonics plates in the western United States. All PBO data are freely available to scientific and educational communities and have been incorporated into a variety of activities for college and university classrooms. UNAVCO Education and Outreach program staff have worked closely with faculty users, scientific researchers, and facility staff to create materials that are scientifically and technically accurate as well as useful to the classroom user. Availability of processed GPS data is not new to the geoscience community. However, PBO data staff have worked with education staff to deliver data that are readily accessible to educators. The UNAVCO Data for Educators webpage, incorporating an embedded Google Map with PBO GPS locations and providing current GPS time series plots and downloadable data, extends and updates the datasets available to our community. Google Earth allows the visualization GPS data with other types of datasets, e.g. LiDAR, while maintaining the self-contained and easy-to-use interface of UNAVCO’s Jules Verne Voyager map tools, which have multiple sets of geological and geophysical data. Curricular materials provide scaffolds for using EarthScope data in a variety of forms for different learning goals. Simple visualization of earthquake epicenters and locations of volcanoes can be used with velocity vectors to make simple deductions of plate boundary behaviors. Readily available time series plots provide opportunities for additional science skills, and there are web and paper-based support materials for downloading data, manipulating tables, and using plotting programs for processed GPS data. Scientists have provided contextual materials to explore the importance of these data in interpreting the structure and dynamics of the Earth. These data

  3. A 3-day regimen with azithromycin 1.5% eyedrops for the treatment of purulent bacterial conjunctivitis in children: efficacy on clinical signs and impact on the burden of illness

    Directory of Open Access Journals (Sweden)

    Bremond-Gignac D

    2015-04-01

    Full Text Available Dominique Bremond-Gignac,1,2 Riadh Messaoud,3 Sihem Lazreg,4 Claude Speeg-Schatz,5 Didier Renault,6 Frédéric Chiambaretta7,8 On behalf of the Azithromycin Pediatric Study Group 1Ophthalmology Department, Centre St Victor, University Hospital of Amiens, Picardie Jules Verne University, Amiens, France; 2CNRS FR3636, Paris V University, France; 3Ophthalmology Department, Tahar Sfar University Hospital, Mahdia, Tunisia; 4Dar El Beida, Blida, Algeria; 5Ophthalmology Department, University Hospital of Strasbourg, Strasbourg, France; 6Laboratoires THÉA, Clermont-Ferrand, France; 7Ophthalmology Department, University Hospital of Clermont-Ferrand, Gabriel Montpied Hospital, Clermont-Ferrand, France; 8EA 7281 R2D2, Auvergne University, Clermont-Ferrand, France Purpose: To compare the efficacy of azithromycin 1.5% versus tobramycin 0.3% eyedrops on clinical ocular signs and symptoms of bacterial conjunctivitis in children and to assess the parents’ satisfaction regarding the dosing regimen.Patients and methods: An international, multicenter, randomized, investigator-masked, controlled clinical trial conducted in children (1 day to 18 years old with bulbar conjunctival hyperemia and purulent discharge. Azithromycin 1.5% was administered as 1 drop twice daily for 3 days, and tobramycin 0.3% as 1 drop every 2 hours for 2 days, then 4 times daily for 5 days.Results: A total of 286 patients (mean age: 3.2 years were enrolled. In children with bacteriologically positive cultures (N=203, azithromycin produced a significantly greater improvement in conjunctival discharge (P<0.01 and a trend (P=0.054 toward improvement in conjunctival hyperemia at day 7 than did tobramycin. Complete resolution of conjunctival discharge was significantly more frequent at day 3 on azithromycin than tobramycin (P=0.005. More parents found azithromycin easier to use (in terms of treatment duration, total number of instillations, instilling drops during the day, and difficulty in

  4. Interaction of Convective Organization and Monsoon Precipitation, Atmosphere, Surface and Sea (INCOMPASS)

    Science.gov (United States)

    Turner, A. G.; Bhat, G. S.; Evans, J. G.; Madan, R.; Marsham, J. H.; Martin, G.; Mitra, A. K.; Mrudula, G.; Parker, D. J.; Pattnaik, S.; Rajagopal, E. N.; Taylor, C.; Tripathi, S. N.

    2016-12-01

    information on the timing of monsoon rain. We also outline our future plans for nested modelling of specific case studies of the 2016 monsoon, at resolutions at of 4km, 2km and 1km with explicit convection, as well as test development of a new 100m model over India. Observations will also be combined with further work using the Joint UK Land Environment Simulator (JULES) model.

  5. Quantitative Assessment of the Potential of Afforestation for Carbon Dioxide Removal: Evaluating carbon sequestration and biogeophysical impacts in a dynamic global vegetation model

    Science.gov (United States)

    Littleton, E. W.

    2015-12-01

    This study presents a new method for representing permanent afforestation in Earth System models. Afforestation has attracted interest as an option to help to slow or reverse the growth of atmospheric carbon dioxide during the next century. However, its potential is poorly constrained with regard to land availability, rates of tree growth and carbon accumulation, and potential side effects. This study aims to provide quantitative assessment of the carbon removal potential and side effects of 21st century afforestation using a dynamic global vegetation model, in contrast to the majority of previous estimates which have used bookkeeping methods. The land surface model JULES was used to simulate needleleaf afforestation on abandoned agricultural land during the 21st century under two future pathways (RCP4.5 and RCP8.5). These results are compared to a control scenario in which natural succession is allowed to act on the same area of land. This study finds considerable spatial variation in the final carbon sequestration potential of afforestation sites. In addition to dieback and marginal growth in many regions, many sites showed minimal additionality of forest areas compared to natural succession. The most suitable sites were in Eastern Europe, central China and central North America. There was no major difference in the general spatial pattern of suitability between RCP4.5 and RCP8.5 by 2100. Overall, this study produced a significantly smaller estimate of the CDR potential of permanent afforestation than previous studies have. The additional carbon stored in suitable sites by 2100 was only 19 Pg C (RCP4.5) and 2.1 Pg C (RCP8.5), a mean of 68 tC/ha. This research also explored the biogeophysical impacts of afforestation on surface energy balance and hydrological cycles. The decrease in albedo caused by afforestation significantly offset the radiative forcing benefits of the carbon removal, although this effect was very sensitive to input assumptions. Flooding results

  6. Metodología para la evaluación de la sostenibilidad en autopistas: cálculo del balance energético de la infraestructura

    Directory of Open Access Journals (Sweden)

    García-Navarro, J.

    2012-10-01

    Full Text Available The work tackles the development of a procedure to evaluate the energetic efficiency in linear infrastructures from a constructive point of view. This procedure allows to calculate the balance of energy along the different phases of life cycle analysis in infrastructure, such as construction, operation - maintenance and deconstruction, both in general and independent terms. Being the target the quantification of energy in the infrastructure, the procedure allows the efficient management of its energy consumption and other environmental impacts, throughout the selection of alternatives and the mitigation or compensation of the balance between its different phases. This paper describes the developed methodology in the procedure, tested by means of a practical example case study, where the embodied energy of one of the functional units in which the motorway is divided (a straight two-way highway stretch is quantified in Jules. The individual amount of different phases is also quantified to establish a balance between them too

    El trabajo aborda el desarrollo de un procedimiento para la evaluación de la eficiencia energética en infraestructuras lineales desde el punto de vista constructivo. El procedimiento permite calcular, tanto globalmente como de forma independizada, el balance energético de las diferentes fases del ciclo de vida de la infraestructura: construcción, operación y desmantelamiento o deconstrucción. Siendo el objetivo la cuantificación de la energía de la infraestructura, el procedimiento permite gestionar eficazmente el consumo de energía y otros impactos ambientales mediante la selección de alternativas y la mitigación o compensación de los balances entre las diferentes fases. En el presente artículo se describe la metodología desarrollada, validándose mediante la aplicación a un caso práctico a modo de ejemplo, cuantificando en Julios la energía embebida en una de las unidades de cálculo o

  7. How well do we characterize the biophysical effects of vegetation cover change? Benchmarking land surface models against satellite observations.

    Science.gov (United States)

    Duveiller, Gregory; Forzieri, Giovanni; Robertson, Eddy; Georgievski, Goran; Li, Wei; Lawrence, Peter; Ciais, Philippe; Pongratz, Julia; Sitch, Stephen; Wiltshire, Andy; Arneth, Almut; Cescatti, Alessandro

    2017-04-01

    Changes in vegetation cover can affect the climate by altering the carbon, water and energy cycles. The main tools to characterize such land-climate interactions for both the past and future are land surface models (LSMs) that can be embedded in larger Earth System models (ESMs). While such models have long been used to characterize the biogeochemical effects of vegetation cover change, their capacity to model biophysical effects accurately across the globe remains unclear due to the complexity of the phenomena. The result of competing biophysical processes on the surface energy balance varies spatially and seasonally, and can lead to warming or cooling depending on the specific vegetation change and on the background climate (e.g. presence of snow or soil moisture). Here we present a global scale benchmarking exercise of four of the most commonly used LSMs (JULES, ORCHIDEE, JSBACH and CLM) against a dedicated dataset of satellite observations. To facilitate the understanding of the causes that lead to discrepancies between simulated and observed data, we focus on pure transitions amongst major plant functional types (PFTs): from different tree types (evergreen broadleaf trees, deciduous broadleaf trees and needleleaf trees) to either grasslands or crops. From the modelling perspective, this entails generating a separate simulation for each PFT in which all 1° by 1° grid cells are uniformly covered with that PFT, and then analysing the differences amongst them in terms of resulting biophysical variables (e.g net radiation, latent and sensible heat). From the satellite perspective, the effect of pure transitions is obtained by unmixing the signal of different 0.05° spatial resolution MODIS products (albedo, latent heat, upwelling longwave radiation) over a local moving window using PFT maps derived from the ESA Climate Change Initiative land cover map. After aggregating to a common spatial support, the observation and model-driven datasets are confronted and

  8. La Convención de los Derechos del Niño veinte años después

    Directory of Open Access Journals (Sweden)

    Ligia Galvis Ortiz

    2009-01-01

    Full Text Available Este ensayo es una reflexión sobre la Convención los Derechos del Niño, con ocasión de sus veinte años de vigencia. El recorrido con el desarrollo de los antecedentes del reconocimiento de los derechos de los niños y niñas en el siglo XIX luego de que autores de la literatura universal como Charles Dickens y Jules Vallès presentaran en sus obras la situación de autoritarismo y maltrato, narrada a partir de sus experiencias. Estas narraciones abrieron el debate en Europa y en América Latina sobre los derechos, y es así como aparecen varios proyectos de Declaración anteriores a la Declaración de Ginebra aprobada por la Sociedad de las Naciones en1924. Estos proyectos se apoyan en el desarrollo conceptual de la nueva pedagogía que también abre sus telones en las últimas décadas del siglo XIX, y acompañan todo el devenir del debate hasta llegar a la aprobación de la Convención, que hoy consagra los derechos de las niñas, niños y adolescentes del planeta. Hago después el análisis de la influencia de ese legado libertario de la pedagogía nueva en el contenido de la Convención, a través de dos entidades centrales que son la titularidad de los derechos y la protección integral con los avances conceptuales que aportan elementos para una interpretación holística, dinámica y actual de la Convención, como son la perspectiva de género, la titularidad activa de los derechos de los niños y niñas, el reconocimiento del mundo de los niños y las niñas y las nuevas miradas sobre la discapacidad, elementos que le aportan un nuevo dinamismo y le imprimen actualidad a los postulados de la Convención.

  9. La Convención de los Derechos del Niño veinte años después

    Directory of Open Access Journals (Sweden)

    Ligia Galvis Ortiz

    2009-10-01

    Full Text Available Este ensayo es una reflexión sobre la Convención los Derechos del Niño, con ocasión de sus veinte años de vigencia. El recorrido con el desarrollo de los antecedentes del reconocimiento de los derechos de los niños y niñas en el siglo XIX luego de que autores de la literatura universal como Charles Dickens y Jules Vallès presentaran en sus obras la situación de autoritarismo y maltrato, narrada a partir de sus experiencias. Estas narraciones abrieron el debate en Europa y en América Latina sobre los derechos, y es así como aparecen varios proyectos de Declaración anteriores a la Declaración de Ginebra aprobada por la Sociedad de las Naciones en1924. Estos proyectos se apoyan en el desarrollo conceptual de la nueva pedagogía que también abre sus telones en las ��ltimas décadas del siglo XIX, y acompañan todo el devenir del debate hasta llegar a la aprobación de la Convención, que hoy consagra los derechos de las niñas, niños y adolescentes del planeta. Hago después el análisis de la influencia de ese legado libertario de la pedagogía nueva en el contenido de la Convención, a través de dos entidades centrales que son la titularidad de los derechos y la protección integral con los avances conceptuales que aportan elementos para una interpretación holística, dinámica y actual de la Convención, como son la perspectiva de género, la titularidad activa de los derechos de los niños y niñas, el reconocimiento del mundo de los niños y las niñas y las nuevas miradas sobre la discapacidad, elementos que le aportan un nuevo dinamismo y le imprimen actualidad a los postulados de la Convención.

  10. Synchronous BRAFV600E and MEK inhibition leads to superior control of murine melanoma by limiting MEK inhibitor induced skin toxicity

    Directory of Open Access Journals (Sweden)

    Gadiot J

    2013-11-01

    Full Text Available Jules Gadiot,1,* Anna I Hooijkaas,1,* Marcel A Deken,1 Christian U Blank1,21Department of Immunology, 2Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands* These authors contributed equally to this workAbstract: The BRAF inhibitor (BRAFi treatment has led to impressive responses in BRAFV600E mutation-positive melanomas, but responses are not durable in many patients. As most of the BRAFi escape mechanisms involve ERK reactivation, combinations with MEK inhibitors (MEKi are currently tested to improve BRAFi-mediated response durations. Additionally, such a combination is expected to reduce MEKi-induced skin toxicities, as these drugs are thought to have antagonistic effects on ERK activation in keratinocytes. However, preclinical in vivo data exploring the combination of BRAFi and MEKi to achieve improved tumor control in the absence of skin toxicities are limited. Using a murine Tyr::CreERT2;PtenLoxP/LoxP;BrafCA/+ melanoma model, we have determined the effect of BRAFi and MEKi treatment and their combination on melanoma control and occurrence of adverse events. We found that the MEKi dosed beyond the maximum tolerable dose (MTD led to stronger control of tumor growth than did the BRAFi, but mice had to be removed from treatment because of skin toxicity. The combination of BRAFi and MEKi reduced MEKi-associated skin toxicity. This allowed high and long-term dosing of the MEKi, resulting in long-term tumor control. In contrast to previous hypotheses, the addition of a BRAFi did not restore the MEKi-mediated downregulation of pErk1/2 in skin cells. Our data describe, for the first time, the alleviation of MEKi-mediated dose-limiting toxicity by addition of a BRAFi in a mouse melanoma model. Additional clinical Phase I studies should be implemented to explore MEKi dosing beyond the single drug MTD in combination with BRAFi.Keywords: melanoma, BRAF, MEK, skin toxicity, vemurafenib, trametinib

  11. Seismic Sensors to Supercomputers: Internet Mapping and Computational Tools for Teaching and Learning about Earthquakes and the Structure of the Earth from Seismology

    Science.gov (United States)

    Meertens, C. M.; Seber, D.; Hamburger, M.

    2004-12-01

    The Internet has become an integral resource in the classrooms and homes of teachers and students. Widespread Web-access to seismic data and analysis tools enhances opportunities for teaching and learning about earthquakes and the structure of the earth from seismic tomography. We will present an overview and demonstration of the UNAVCO Voyager Java- and Javascript-based mapping tools (jules.unavco.org) and the Cornell University/San Diego Supercomputer Center (www.discoverourearth.org) Java-based data analysis and mapping tools. These map tools, datasets, and related educational websites have been developed and tested by collaborative teams of scientific programmers, research scientists, and educators. Dual-use by research and education communities ensures persistence of the tools and data, motivates on-going development, and encourages fresh content. With these tools are curricular materials and on-going evaluation processes that are essential for an effective application in the classroom. The map tools provide not only seismological data and tomographic models of the earth's interior, but also a wealth of associated map data such as topography, gravity, sea-floor age, plate tectonic motions and strain rates determined from GPS geodesy, seismic hazard maps, stress, and a host of geographical data. These additional datasets help to provide context and enable comparisons leading to an integrated view of the planet and the on-going processes that shape it. Emerging Cyberinfrastructure projects such as the NSF-funded GEON Information Technology Research project (www.geongrid.org) are developing grid/web services, advanced visualization software, distributed databases and data sharing methods, concept-based search mechanisms, and grid-computing resources for earth science and education. These developments in infrastructure seek to extend the access to data and to complex modeling tools from the hands of a few researchers to a much broader set of users. The GEON

  12. Interactions between nitrogen deposition, land cover conversion, and climate change determine the contemporary carbon balance of Europe

    Directory of Open Access Journals (Sweden)

    G. Churkina

    2010-09-01

    Full Text Available European ecosystems are thought to take up large amounts of carbon, but neither the rate nor the contributions of the underlying processes are well known. In the second half of the 20th century, carbon dioxide concentrations have risen by more that 100 ppm, atmospheric nitrogen deposition has more than doubled, and European mean temperatures were increasing by 0.02 °C yr−1. The extents of forest and grasslands have increased with the respective rates of 5800 km2 yr−1 and 1100 km2 yr−1 as agricultural land has been abandoned at a rate of 7000 km2 yr−1. In this study, we analyze the responses of European land ecosystems to the aforementioned environmental changes using results from four process-based ecosystem models: BIOME-BGC, JULES, ORCHIDEE, and O-CN. The models suggest that European ecosystems sequester carbon at a rate of 56 TgC yr−1 (mean of four models for 1951–2000 with strong interannual variability (±88 TgC yr−1, average across models and substantial inter-model uncertainty (±39 TgC yr−1. Decadal budgets suggest that there has been a continuous increase in the mean net carbon storage of ecosystems from 85 TgC yr−1 in 1980s to 108 TgC yr−1 in 1990s, and to 114 TgC yr−1 in 2000–2007. The physiological effect of rising CO2 in combination with nitrogen deposition and forest re-growth have been identified as the important explanatory factors for this net carbon storage. Changes in the growth of woody vegetation are suggested as an important contributor to the European carbon sink. Simulated ecosystem responses were more consistent for the two models accounting for terrestrial carbon-nitrogen dynamics than for the two models which only accounted for carbon cycling and the effects of land cover change. Studies of the interactions of carbon-nitrogen dynamics with

  13. New estimates of temperature response of leaf photosynthesis in Amazon forest trees, its acclimation to mean temperature change and consequences for modelling climate response to rain forests.

    Science.gov (United States)

    Kruijt, B.; Jans, W.; Vasconcelos, S.; Tribuzy, E. S.; Felsemburgh, C.; Eliane, M.; Rowland, L.; da Costa, A. C. L.; Meir, P.

    2014-12-01

    In many dynamic vegetation models, degradation of the tropical forests is induced because they assume that productivity falls rapidly when temperatures rise in the region of 30-40°C. Apart plant respiration, this is due to the assumptions on the temperature optima of photosynthetic capacity, which are low and can differ widely between models, where in fact hardly any empirical information is available for tropical forests. Even less is known about the possibility that photosynthesis will acclimate to changing temperatures. The objective of this study to is to provide better estimates for optima, as well as to determine whether any acclimation to temperature change is to be expected. We present both new and hitherto unpublished data on the temperature response of photosynthesis of Amazon rainforest trees, encompassing three sites, several species and five field campaigns. Leaf photosynthesis and its parameters were determined at a range of temperatures. To study the long-term (seasonal) acclimation of this response, this was combined with an artificial, in situ, multi-season leaf heating experiment. The data show that, on average for all non-heated cases, the photosynthetic parameter Vcmax weakly peaks between 35 and 40 ˚C, while heating does not have a clearly significant effect. Results for Jmax are slightly different, with sharper peaks. Scatter was relatively high, which could indicate weak overall temperature dependence. The combined results were used to fit new parameters to the various temperature response curve functions in a range of DGVMs. The figure shows a typical example: while the default Jules model assumes a temperature optimum for Vcmax at around 33 ˚C, the data suggest that Vcmax keeps rising up to at least 40 ˚C. Of course, calculated photosynthesis, obtained by applying this Vcmax in the Farquhar model, peaks at lower temperature. Finally, the implication of these new model parameters for modelled climate change impact on modelled Amazon

  14. Climate-related large-scale variation in forest carbon turnover rate - Evaluating global vegetation models using remote sensing products of biomass and NPP

    Science.gov (United States)

    Thurner, Martin; Beer, Christian; Carvalhais, Nuno; Ciais, Philippe; Forkel, Matthias; Friend, Andrew; Ito, Akihiko; Kleidon, Axel; Lomas, Mark; Quegan, Shaun; Tito Rademacher, Tim; Santoro, Maurizio; Schaphoff, Sibyll; Schmullius, Christiane; Tum, Markus; Wiltshire, Andy

    2017-04-01

    Vegetation carbon turnover, in terms of its spatial variation and its response to climate change, is one of the most important, but also most uncertain carbon fluxes in terrestrial ecosystems. Its measurement is hardly possible by inventory studies alone, due to several reasons: First, vegetation carbon turnover involves a variety of processes, including litterfall, background mortality, and mortality by all kinds of disturbances, affecting single biomass compartments, individual trees or even whole ecosystems. Second, these processes act on very different timescales, involving short-term extreme events and long-term responses, and spatial scales, from local extremes to global impacts. In order to capture this variety of processes, spatial scales and timescales, here we estimate forest carbon turnover rate from novel remote sensing products of NPP and biomass. These products allow investigating the spatial variation in long-term mean turnover rate at 0.5° resolution across northern boreal and temperate forest ecosystems and its relation to climate variables. We observe an increase in turnover rate with colder and longer winters in boreal forests, whereas in temperate forests the spatial gradients in turnover rate are related to the length of both warm and dry periods. Thus, we hypothesize that the spatial variation in turnover rate can be explained by direct and indirect frost damage effects on mortality in boreal forests but drought and insect outbreaks in temperate forests. An evaluation of a set of global vegetation models (GVMs) participating in the Inter-Sectoral Impact Model Intercomparison Project (ISI-MIP; including HYBRID4, JeDi, JULES, LPJml, ORCHIDEE, SDGVM, VISIT) shows that those models are able to reproduce the observation-based spatial relationships only to a limited extent. Deviations from the observation-based turnover rates can be mostly attributed to severe overestimations of biomass, however also important differences in the simulated spatial

  15. Alfred Vulpian and Jean-Martin Charcot in each other's shadow? From Castor and Pollux at La Salpêtrière to neurology forever.

    Science.gov (United States)

    Bogousslavsky, Julien; Walusinski, Olivier; Moulin, Thierry

    2011-01-01

    While Alfred Vulpian (1826-1887) is not completely forgotten, he cannot match the uninterrupted celebrity which Jean-Martin Charcot (1825-1893) still enjoys today. After becoming interne (residents) at the same institute in 1848, both were involved in shaping the cradle of what would become modern neurology. Both started work as chiefs at a La Salpêtrière service on January 1, 1862, making common rounds and studies, with several common publications. While their friendship remained 'for life', as stated by Charcot at Vulpian's funeral, their career paths differed. Vulpian progressed quicker and higher, being appointed full professor and elected at the Académie Nationale de Médecine and the Académie des Sciences several years before Charcot, as well as becoming dean of the Paris Faculty of Medicine. These positions also enabled him to support his friend Charcot in getting appointed full clinical professor and becoming the first holder of the chair of Clinique des Maladies du Système Nerveux in 1882. Before studying medicine, Vulpian had worked in physiology with Pierre Flourens, and his career always remained balanced between physiology and neurology, with remarkable papers. He introduced Charcot to optic microscopy during their La Salpêtrière years, indirectly helping him to become his successor to the chair of pathological anatomy in 1872. While Vulpian succeeded so well in local medical affairs, Charcot spent his time building up a huge clinical service and a teaching 'school' at La Salpêtrière, which he never left for over 31 years until his death. This 'school' progressively became synonymous with clinical neurology itself and perpetuated the master's memory for decades. Vulpian never had such support, although Jules Déjerine was his pupil and Joseph Babinski was his interne before becoming Charcot's chef de clinique (chief of staff) in 1885. This unusual switch in Parisian medicine contributed to Charcot's unaltered celebrity over more than a century

  16. Paired-eye comparison of medical therapies for glaucoma

    Directory of Open Access Journals (Sweden)

    Alfred M Solish

    2010-09-01

    Full Text Available Alfred M Solish1,2, Friedericke James1, John G Walt3, Tina H Chiang31Southern California Glaucoma Consultants, Pasadena CA, USA; 2Jules Stein Eye Institute, University of California Los Angeles, Los Angeles, 3Allergan Inc., Irvine, CA, USA Objective: To evaluate efficacy and patient preference retrospectively among intraocular pressure (IOP-lowering prostamide and prostaglandin medications in a real-world clinical setting.Methods: Chart review of patients with uncontrolled glaucoma or ocular hypertension seen at a private practice clinic (n = 55 who received bimatoprost 0.03% once daily in one eye and either travoprost 0.004% or latanoprost 0.005% once daily in the fellow eye. IOP was evaluated at the initial visit and at a follow-up visit scheduled 4–6 weeks later. At the follow-up visit, each patient discussed the clinical results with their physician, chose which medication they preferred to continue using, and were queried regarding the reason for their choice. This paired-eye comparison method is used routinely in clinical practice to assess clinical response and involve patients in decisions regarding treatment. Change in mean IOP from baseline and patient medication choice were the outcome measures.Results: Bimatoprost-treated eyes (n = 52 had a mean IOP reduction of 2.7 mmHg and travoprost-treated eyes (n = 47 had an average decrease of 1.7 mmHg (P = 0.230. Bimatoprost significantly reduced mean IOP (from 19.8 mmHg at baseline to 17.1 mmHg at follow-up, P < 0.0001, as did travoprost (from 19.4 mmHg at baseline to 17.7 mmHg at follow-up, P = 0.009. Latanoprost-treated eyes were excluded from the efficacy analysis due to small sample size (n = 5. For continued therapy, patients chose bimatoprost over travoprost by a factor of 2.4 to 1. Of the 15 patients who gave a reason for their choice, 80% said their decision was based primarily on IOP change.Conclusions: Bimatoprost and travoprost were efficacious in reducing IOP among patients with

  17. Pain Management: Road Map to Revolution.

    Science.gov (United States)

    George, Steven Z

    2017-02-01

    Lindblom Young Investigator Award for Clinical Sciences from the International Association for the Study of Pain, the Florida Physical Therapy Association's Award for Scholarly Impact on Practice, and APTA's Jules M. Rothstein Golden Pen Award and Eugene Michels New Investigator Award. In 2014, George's innovative knowledge contributed to being identified by Expertscape as the 10th-ranked world expert for scholarly contributions to the understanding and treatment of back pain. Expertscape's ranking, based on the quantity and quality of peer-reviewed clinical research publications in the National Library of Medicine's MEDLINE database, highlights George's status as a visionary in the profession. For his advocacy toward conducting meaningful research, expertise on pain management, and profound impact beyond published works, APTA is pleased to honor Steven Z. George as the 2016 John H.P. Maley Lecturer.

  18. The visual difficulties of selected artists and limitations of ophthalmological care during the 19th and early 20th centuries (an AOS thesis).

    Science.gov (United States)

    Ravin, James G

    2008-01-01

    To investigate the effects of eye diseases on several important artists who have been given little attention from a medical-historical viewpoint. The examples chosen demonstrate problems artists have had to face from different types of eye disease, including cataract, glaucoma, and retinal diseases. The ophthalmological care provided is described in terms of scientific knowledge at the time. Investigation of primary and secondary source material. Discussion with art historians and ophthalmic historians. Examination of work by the artists. Artists can be markedly affected by ocular diseases that change their ability to see the world. The individuals described here worked during the 19th century and first half of the 20th century. Homer Martin suffered from cataracts, and his works reveal changes in details and color as he aged. Henri Harpignies, who had an extremely long career, undoubtedly had cataracts and may also have had macular degeneration. Angle-closure glaucoma blinded Jules Chéret. Auguste Ravier suffered from neovascular glaucoma in one eye and was able to work with his remaining eye, which developed a cataract. Louis Valtat suffered from what was in all likelihood open-angle glaucoma, but specific changes due to this disease are not apparent in his work. Roger Bissière developed glaucoma and did well following filtration surgery. George Du Maurier lost one eye from what was probably a retinal detachment and later suffered from a central retinal problem in the other eye. Diseases of the eye may profoundly influence artists by altering their perception of the world. The specific effects may vary, depending on the disease, its severity, and the psychology of the artist. Cataracts typically affect an artist's ability to depict color and detail. The effect of glaucoma generally depends on whether central vision is preserved. Disease that affects the center of the retina has a substantial effect on an artist's ability to depict fine details. Ophthalmological

  19. An integrated, cross-disciplinary study of soil hydrophobicity at atomic, molecular, core and landscape scales

    Science.gov (United States)

    Matthews, G. Peter; Doerr, Stefan; Van Keulen, Geertje; Dudley, Ed; Francis, Lewis; Whalley, Richard; Gazze, Andrea; Hallin, Ingrid; Quinn, Gerry; Sinclair, Kat; Ashton, Rhys

    2017-04-01

    by ESI and MALDI TOF mass spectrometry and database searches, (ii) the examination of such proteins, which form ordered hydrophobic ridges, and measurement of their elasticity, stickiness and hydrophobicity at nano- to microscale using atomic force microscopy adapted for the rough surfaces of soil particles, (iii) the novel use of a picoliter goniometer to show hydrophobic effects at a 1 micron diameter droplet level, which avoids the averaging over soil cores and particles evident in microliter goniometry, with which the results are compared, (iv) measurements at core scale using water retention and wicking experiments, and (v) the modelling and upscaling of the results from molecular to core scale using the PoreXpert void network model of dynamic wetting and Haines jumps. An explanation will also be given as to how the results will be further upscaled by incorporation into the JULES hydrological model of the UK Meteorological Office, used to predict flooding for different soil types and usage.

  20. Analysis of the linearised observation operator in a soil moisture and temperature analysis scheme

    Science.gov (United States)

    Dharssi, I.; Candy, B.; Steinle, P.

    2015-06-01

    Several weather forecasting agencies have developed advanced land data assimilation systems that, in principle, can analyse any model land variable. Such systems can make use of a wide variety of observation types, such as screen level (2 m above the surface) observations and satellite based measurements of surface soil moisture and skin temperature. Indirect measurements can be used and information propagated from the surface into the deeper soil layers. A key component of the system is the calculation of the linearised observation operator matrix (Jacobian matrix) which describes the link between the observations and the land surface model variables. The elements of the Jacobian matrix (Jacobians) are estimated using finite difference by performing short model forecasts with perturbed initial conditions. The calculated Jacobians show that there can be strong coupling between the screen level and the soil. The coupling between the screen level and surface soil moisture is found to be due to a number of processes including bare soil evaporation, soil thermal conductivity as well as transpiration by plants. Therefore, there is significant coupling both during the day and at night. The coupling between the screen level and root-zone soil moisture is primarily through transpiration by plants. Therefore the coupling is only significant during the day and the vertical variation of the coupling is modulated by the vegetation root depths. The calculated Jacobians that link screen level temperature to model soil temperature are found to be largest for the topmost model soil layer and become very small for the lower soil layers. These values are largest during the night and generally positive in value. It is found that the Jacobians that link observations of surface soil moisture to model soil moisture are strongly affected by the soil hydraulic conductivity. Generally, for the Joint UK Land Environment Simulator (JULES) land surface model, the coupling between the surface

  1. Needs of Accurate Prompt and Delayed γ-spectrum and Multiplicity for Nuclear Reactor Designs

    Science.gov (United States)

    Rimpault, G.; Bernard, D.; Blanchet, D.; Vaglio-Gaudard, C.; Ravaux, S.; Santamarina, A.

    The local energy photon deposit must be accounted accurately for Gen-IV fast reactors, advanced light-water nuclear reactors (Gen-III+) and the new experimental Jules Horowitz Reactor (JHR). The γ energy accounts for about 10% of the total energy released in the core of a thermal or fast reactor. The γ-energy release is much greater in the core of the reactor than in its structural sub-assemblies (such as reflector, control rod followers, dummy sub-assemblies). However, because of the propagation of γ from the core regions to the neighboring fuel-free assemblies, the contribution of γ energy to the total heating can be dominant. For reasons related to their performance, power reactors require a 7.5% (1σ) uncertainty for the energy deposition in non-fuelled zones. For the JHR material-testing reactor, a 5% (1 s) uncertainty is required in experimental positions. In order to verify the adequacy of the calculation of γ-heating, TLD and γ-fission chambers were used to derive the experimental heating values. Experimental programs were and are still conducted in different Cadarache facilities such as MASURCA (for SFR), MINERVE and EOLE (for JHR and Gen-III+ reactors). The comparison of calculated and measured γ-heating values shows an underestimation in all experimental programs indicating that for the most γ-production data from 239Pu in current nuclear-data libraries is highly suspicious.The first evaluation priority is for prompt γ-multiplicity for U and Pu fission but similar values for otheractinides such as Pu and U are also required. The nuclear data library JEFF3.1.1 contains most of the photon production data. However, there are some nuclei for which there are missing or erroneous data which need to be completed or modified. A review of the data available shows a lack of measurements for conducting serious evaluation efforts. New measurements are needed to guide new evaluation efforts which benefit from consolidated modeling techniques.

  2. Secondary structure adventures with Carl Woese.

    Science.gov (United States)

    Noller, Harry F

    2014-01-01

    Not long after my arrival at UCSC as an assistant professor, I came across Carl Woese's paper "Molecular Mechanics of Translation: A Reciprocating Ratchet Mechanism." (1) In the days before the crystal structure of tRNA was known, Fuller and Hodgson (2) had proposed two alternative conformations for its anticodon loop; one was stacked on the 3' side (as later found in the crystal structure) and the other on the 5' side. In an ingenious and elegant model, Woese proposed that the conformation of the loop flips between Fuller and Hodgson's 5'- and 3'-stacked forms during protein synthesis, changing the local direction of the mRNA such that the identities of the tRNA binding sites alternated between binding aminoacyl-tRNA and peptidyl-tRNA. The model predicted that there are no A and P sites, only two binding sites whose identities changed following translation of each codon, and that there would be no translocation of tRNAs in the usual sense--only binding and release. I met Carl in person the following year when he presented a seminar on his ratchet model in Santa Cruz. He was chatting in my colleague Ralph Hinegardner's office in what Carl termed a "Little Jack Horner appointment" (the visitor sits and listens to his host describing "What a good boy am I"). He was of compact stature, and bore a striking resemblance to Oskar Werner in Truffaut's film "Jules and Jim." He projected the impression of a New-Age guru--a shiny black amulet suspended over the front of his black turtleneck sweater and a crown of prematurely white hair. Ralph asked me to explain to Carl what we were doing with ribosomes. I quickly summarized our early experiments that were pointing to a functional role for 16S rRNA. Carl regarded me silently, with a penetrating stare. He then turned to Ralph and said, in an ominous low voice, "I'm going to have some more tanks made as soon as I get back." Carl's beautiful model was, unfortunately, wrong--it was simpler and more elegant than the complex

  3. Soil hydrophobicity - relating effects at atomic, molecular, core and national scales

    Science.gov (United States)

    Matthews, Peter; Doerr, Stefan; Van Keulen, Geertje; Dudley, Ed; Francis, Lewis; Whalley, Richard; Gazze, Andrea; Hallin, Ingrid; Quinn, Gerry; Sinclair, Kat; Ashton, Rhys

    2016-04-01

    avoids the averaging over soil cores and particles evident in microliter goniometry, with which the results are compared, (iv) measurements at core scale using water retention and wicking experiments, and (v) the interpretation, integration and upscaling of the results using a development of the PoreXpert void network model, a significant advance on the Van Genuchten approach. An explanation will also be given as to how the results will be incorporated into the JULES hydrological model of the UK Meteorological Office, used to predict flooding for different soil types and usage.

  4. Safety of long-term use of linezolid: results of an open-label study

    Directory of Open Access Journals (Sweden)

    Vazquez JA

    2016-09-01

    Full Text Available Jose A Vazquez,1 Anthony C Arnold,2 Robert N Swanson,3 Pinaki Biswas,3 Matteo Bassetti4 1Section of Infectious Diseases, Medical College of Georgia, Georgia Regents University, Augusta, GA, USA; 2UCLA Department of Ophthalmology, Jules Stein Eye Institute, Los Angeles, CA, USA; 3Clinical Research, Global Innovative Pharmaceutical, Pfizer Inc., New York, NY, USA; 4Infectious Diseases Division, Santa Maria della Misericordia University Hospital, Udine, Italy Objective: The objective of this study was to assess the long-term safety of linezolid in patients with chronic infections requiring treatment for ≥6 weeks. Enhanced monitoring for optic neuropathy was included to characterize the early development of this side effect and to identify ophthalmologic tests that might be valuable in early detection of this event. Methods: This was a multicenter, open-label, pilot study of patients aged ≥18 years on long-term linezolid therapy. Matched control patients were included for baseline assessment comparison. Patients were assessed at study entry, monthly while on treatment, at the end of treatment, and 30 days following the last dose. Aggregate ocular safety data were reviewed. Response to treatment was reported. Results: The study was terminated owing to slow enrollment. Twenty-four patients received linezolid; nine patients were included as matched controls. Linezolid was prescribed for a median of 80.5 days (range, 50–254 days. In patients with a reported clinical outcome, the majority were considered improved or cured. Common treatment-related adverse events (AEs included anemia, peripheral neuropathy, polyneuropathy, vomiting, and asthenia, and were consistent with the known safety profile. Most AEs resolved or stabilized with discontinuation of treatment. Results of ophthalmologic tests in the one case adjudicated as probable linezolid-associated optic neuropathy revealed abnormal color vision, characteristic changes in the optic disk

  5. Carbon stock and carbon turnover in boreal and temperate forests - Integration of remote sensing data and global vegetation models

    Science.gov (United States)

    Thurner, Martin; Beer, Christian; Carvalhais, Nuno; Forkel, Matthias; Tito Rademacher, Tim; Santoro, Maurizio; Tum, Markus; Schmullius, Christiane

    2016-04-01

    Long-term vegetation dynamics are one of the key uncertainties of the carbon cycle. There are large differences in simulated vegetation carbon stocks and fluxes including productivity, respiration and carbon turnover between global vegetation models. Especially the implementation of climate-related mortality processes, for instance drought, fire, frost or insect effects, is often lacking or insufficient in current models and their importance at global scale is highly uncertain. These shortcomings have been due to the lack of spatially extensive information on vegetation carbon stocks, which cannot be provided by inventory data alone. Instead, we recently have been able to estimate northern boreal and temperate forest carbon stocks based on radar remote sensing data. Our spatially explicit product (0.01° resolution) shows strong agreement to inventory-based estimates at a regional scale and allows for a spatial evaluation of carbon stocks and dynamics simulated by global vegetation models. By combining this state-of-the-art biomass product and NPP datasets originating from remote sensing, we are able to study the relation between carbon turnover rate and a set of climate indices in northern boreal and temperate forests along spatial gradients. We observe an increasing turnover rate with colder winter temperatures and longer winters in boreal forests, suggesting frost damage and the trade-off between frost adaptation and growth being important mortality processes in this ecosystem. In contrast, turnover rate increases with climatic conditions favouring drought and insect outbreaks in temperate forests. Investigated global vegetation models from the Inter-Sectoral Impact Model Intercomparison Project (ISI-MIP), including HYBRID4, JeDi, JULES, LPJml, ORCHIDEE, SDGVM, and VISIT, are able to reproduce observation-based spatial climate - turnover rate relationships only to a limited extent. While most of the models compare relatively well in terms of NPP, simulated

  6. Wisconsin builds a distributed resources collaborative: Looking for local solutions that work

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, C.

    1995-12-01

    I`d like to tell you how I got involved in the DR Collaborative and why I`m here. John Nesbitt asked me to come, to be the public advocate, the bumblebee on the EPRI body politic. What follows is my own thought, not that of John or my fellow collaborators, who may or may not agree with me. How did I come to know John Nesbitt? In August 1991, I found that some Wisconsin utilities intended to run a 138 kV transmission line across my property, along the driveway where my kids ride their bikes, along the high ground where we walk to escape the mosquitoes in the summer, where we ski cross-country and admire the snowy view in the winter. As a result, I became intensely interested in the electric power business. One thing led to another. I got on the Board of Wisconsin Demand-Side Demonstrations (WDSD), representing a group called the Citizens` Utility Board (CUB). I met Mr. Nesbitt. We shared an interest in distributed resources (DR). Along with some others, we conspired to initiate the Targeted Area Planning (TAP) collaborative. TAP is what we call DR in Wisconsin. I began to talk in acronyms. The simple truth is, I detest transmission lines. And, since transmission lines are invariably hooked up to central generation, I have no love for big power plants either. That whole system approach looks excessive and outdated to me, a vestige of the nineteenth century, Jules Verne without the romance. My opinion is, who needs it? I am aware that my opinion is not shared by everyone. I grant you that transmission lines might be a mite more acceptable if the thousands of landowners like me who presently subsidize their existence were receiving compensation, say an annual commodity transfer fee, that reflected some small portion of the value of transmission lines in the present system. That is certainly not the case, and if it were, the present system, when and if deregulated, would price itself out of existence all the more quickly.

  7. JHR Project: a future Material Testing Reactor working as an International user Facility: The key-role of instrumentation in support to the development of modern experimental capacity

    Energy Technology Data Exchange (ETDEWEB)

    Bignan, G. [CEA, DEN, DER, JHR user Facility Interface Manager' , Cadarache, F-13108 St-Paul-Lez-Durance (France); Gonnier, C. [CEA, DEN, DER, SRJH Jules Horowitz Reactor Service, Cadarache, F-13108 St-Paul-Lez-Durance (France); Lyoussi, A.; Villard, J.F.; Destouches, C. [CEA, DEN, DER, Instrumentation Sensors and Dosimetry Laboratory, Cadarache, F-13108 St-Paul-Lez-Durance (France); Chauvin, J.P. [CEA,DEN, DER, SPEX, Experimental Physics Service, Cadarache, F-13108 St-Paul-Lez-Durance (France); Maugard, B. [CEA, DEN, DER, Reactor Department Studies, Cadarache, F-13108 St-Paul-Lez-Durance (France)

    2015-07-01

    Research and development on fuel and material behaviour under irradiation is a key issue for sustainable nuclear energy in order to meet specific needs by keeping the best level of safety. These needs mainly deal with a constant improvement of performances and safety in order to optimize the fuel cycle and hence to reach nuclear energy sustainable objectives. A sustainable nuclear energy requires a high level of performances in order to meet specific needs such as: - Pursuing improvement of the performances and safety of present and coming water cooled reactor technologies. This will require a continuous R and D support following a long-term trend driven by the plant life management, safety demonstration, flexibility and economics improvement. Experimental irradiations of structure materials are necessary to anticipate these material behaviours and will contribute to their optimisation. - Upgrading continuously nuclear fuel technology in present and future nuclear power plants to achieve better performances and to optimise the fuel cycle keeping the best level of safety. Fuel evolution for generation II, III and III+ is a key stake requiring developments, qualification tests and safety experiments to ensure the competitiveness and safety: experimental tests exploring the full range of fuel behaviour determine fuel stability limits and safety margins, as a major input for the fuel reliability analysis. To perform such accurate and innovative progress and developments, specific and ad hoc instrumentation, irradiation devices, measurement methods are necessary to be set up inside or beside the material testing reactor (MTR) core. These experiments require beforehand in situ and on line sophisticated measurements to accurately determine different key parameters such as thermal and fast neutron fluxes and nuclear heating in order to precisely monitor and control the conducted assays. The new Material Testing Reactor JHR (Jules Horowitz Reactor) currently under

  8. Effects of biomass burning aerosols on CO2 fluxes on Amazon Region

    Science.gov (United States)

    Soares Moreira, Demerval; Freitas, Saulo; Longo, Karla; Rosario, Nilton

    2015-04-01

    During the dry season in Central Brazil and Southern Amazon, there is an usually high concentration of aerosol particles associated with intense human activities, with extensive biomass burning. It has been observed through remote sensing that the smoke clouds in these areas often cover an area of about 4 to 5 million km2. Thus, the average aerosol optical depth of these regions at 500 ηm, is usually below 0.1 during the rainy season and can exceed 0.9 in the fire season. Aerosol particles act as condensation nuclei and also increase scattering and absorption of the incident radiation. Therefore, the layer of the aerosol alters the precipitation rate; reduces the amount of solar energy that reaches the surface, producing a cooling; and causes an increase of diffuse radiation. These factors directly and indirectly affect the CO2 fluxes at the surface. In this work, the chemical-atmospheric model CCATT-BRAMS (Coupled Chemistry-Aerosol-Tracer Transport model to the Brazilian developments on the Regional Atmospheric Modeling System) coupled to the surface model JULES (Joint UK Land Environment Simulator) was used to simulate the effects of biomass burning aerosols in CO2 fluxes in the Amazon region. Both the total effect of the aerosols and the contribution related only to the increase of the diffuse fraction caused by the their presence were analyzed. The results show that the effect of the scattered fraction is dominant over all other effects. It was also noted that the presence of aerosols from fires can substantially change biophysiological processes of the carbon cycle. In some situations, it can lead to a sign change in the net ecosystem exchange (NEE), turning it from a source of CO2 to the atmosphere, when the aerosol is not considered in the simulations, to a sink, when it is considered. Thus, this work demonstrates the importance of considering the presence of aerosols in numerical simulations of weather and climate, since carbon dioxide is a major

  9. Effects of Biomass Burning Aerosols on CO2 Fluxes in the Amazon Region

    Science.gov (United States)

    Moreira, D. S.; Freitas, S. R.

    2014-12-01

    During the dry season in Central Brazil and Southern Amazon, there is an usually high concentration of aerosol particles associated with intense human activities, with extensive biomass burning. It has been observed through remote sensing that the smoke clouds in these areas often cover an area of about 4 to 5 million km2. Thus, the average aerosol optical depth of these regions at 500 ηm, is usually below 0.1 during the rainy season and can exceed 0.9 in the fire season. Aerosol particles act as condensation nuclei and also increase scattering and absorption of the incident radiation. Therefore, the layer of the aerosol alters the precipitation rate; reduces the amount of solar energy that reaches the surface, producing a cooling; and causes an increase of diffuse radiation. These factors directly and indirectly affect the CO2 fluxes at the surface. In this work, the chemical-atmospheric model CCATT-BRAMS (Coupled Chemistry-Aerosol-Tracer Transport model to the Brazilian developments on the Regional Atmospheric Modeling System) coupled to the surface model JULES (Joint UK Land Environment Simulator) was used to simulate the effects of biomass burning aerosols in CO2 fluxes in the Amazon region. Both the total effect of the aerosols and the contribution related only to the increase of the diffuse fraction caused by the their presence were analyzed. The results show that the effect of the scattered fraction is dominant over all other effects. It was also noted that the presence of aerosols from fires can substantially change biophysiological processes of the carbon cycle. In some situations, it can lead to a sign change in the net ecosystem exchange (NEE), turning it from a source of CO2 to the atmosphere, when the aerosol is not considered in the simulations, to a sink, when it is considered. Thus, this work demonstrates the importance of considering the presence of aerosols in numerical simulations of weather and climate, since carbon dioxide is a major

  10. Delayed Gamma Measurements in Different Nuclear Research Reactors Bringing Out the Importance of the Delayed Contribution in Gamma Flux Calculations

    Energy Technology Data Exchange (ETDEWEB)

    Fourmentel, D.; Radulovic, V.; Barbot, L.; Villard, J-F. [Alternative Energies and Atomic Energy Commission, CEA, DEN, DER, Instrumentation Sensors and Dosimetry Laboratory, Cadarache, 13108 Saint- Paul-Lez-Durance (France); Zerovnik, G.; Snoj, L. [Reactor Physics Department, Jozef Stefan Institute, SI-1000 Ljubljana (Slovenia); Tarchalski, M.; Pytel, K. [National Centre for Nuclear Research A. Soltana 7, 05-400 Swierk (Poland); Malouch, F. [Alternative Energies and Atomic Energy Commission - CEA, DEN, DM2S, Saclay, 91191, Gif-sur-Yvette (France)

    2015-07-01

    Neutron and gamma flux levels are key parameters in nuclear research reactors. In Material Testing Reactors, such as the future Jules Horowitz Reactor, under construction at the French Alternative Energies and Atomic Energy Commission (CEA Cadarache, France), the expected gamma flux levels are very high (nuclear heating is of the order of 20 W/g at 100 MWth). As gamma rays deposit their energy in the reactor structures and structural materials it is important to take them into account when designing irradiation devices. There are only a few sensors which allow measurements of the nuclear heating ; a recent development at the CEA Cadarache allows measurements of the gamma flux using a miniature ionization chamber (MIC). The measured MIC response is often compared with calculation using modern Monte Carlo (MC) neutron and photon transport codes, such as TRIPOLI-4 and MCNP6. In these calculations only the production of prompt gamma rays in the reactor is usually modelled thus neglecting the delayed gamma rays. Hence calculations and measurements are usually in better accordance for the neutron flux than for the gamma flux. In this paper we study the contribution of delayed gamma rays to the total MIC signal in order to estimate the systematic error in gamma flux MC calculations. In order to experimentally determine the delayed gamma flux contributions to the MIC response, we performed gamma flux measurements with CEA developed MIC at three different research reactors: the OSIRIS reactor (MTR - 70 MWth at CEA Saclay, France), the TRIGA MARK II reactor (TRIGA - 250 kWth at the Jozef Stefan Institute, Slovenia) and the MARIA reactor (MTR - 30 MWth at the National Center for Nuclear Research, Poland). In order to experimentally assess the delayed gamma flux contribution to the total gamma flux, several reactor shut down (scram) experiments were performed specifically for the purpose of the measurements. Results show that on average about 30 % of the MIC signal is due to

  11. Le Laboratoire de Mécanique Appliquée Raymond Chaléat a 40 ans !

    Science.gov (United States)

    Comité D'Organisation Du Colloque Ime 2002, Le

    2002-12-01

    Le LMARC a été créé par Raymond Chaléat dans les locaux de l'École Nationale d'Horlogerie (a présent Lycée Technique Jules Haag).L'équipe de recherche était alors constituée de 2 enseignants-chercheurs (Raymond Chaléat et Gérard Lallement) et d'un technicien (Bernard Prêtre). Les travaux de recherche se situaient naturellement dans le domaine de la chronométrie et en particulier dans la mécanique non linéaire analytique inhérente à la montre en fonctionnement. En effet, Raymond Chaléat fut l'élève, puis le collaborateur du Professeur Jules Haag, mathématicien et mécanicien, lui-même élève de Poincarré.Le LMARC a étendu ses activités avec l'arrivée de Claude Oudet, puis de Claude Oytana à la rhéologie des matériaux solides qui est devenue plus tard l'Équipe Propriétés Mécaniques des Matériaux. En parallèle, G. Lallement a créé une équipe Vibrations devenue à ce jour Dynamique des Structures. À ce jour, le Laboratoire compte plus de 110 personnes dont 40 doctorants.Il a depuis diversifié ses activités avec 3 nouvelles équipes tournées vers la Modélisation et la Mise en Forme des Matériaux, les Micromachines et la Biomécanique et les Mécanismes. Il a su également prendre toute sa place au sein de l'Institut des Microtechniques de Franche-Comté en contribuant à plusieurs thèmes.Notre Laboratoire a été l'un des premiers laboratoires associé au CNRS (4ème) et a toujours été rattaché à l'Université de Franche-Comté (Présidence par C. Oytana de 1996 a 2001) par l'entremise de I'UFR Sciences et Techniques. Il a toujours maintenu des liens forts avec I'ENSMM (École Nationale Supérieure de Mécanique et des Microtechniques) d'une part par ses enseignants-chercheurs et d'autre part deux de ses directeurs, Raymond Chaléat et actuellement Jean-Claude Gelin.En plus de ses relations constantes avec l'industrie régionale, le LMARC a développé des actions contractuelles avec de grands groupes tels que EDF

  12. Toll样受体和树突状细胞:免疫激活传感器——2011年诺贝尔生理学或医学奖简介%Toll Like-receptors and Dendritic Cells: Sensors for the Activation of Immune Response - A Brief Introduction to the 2011 Nobel Prize in Physiology or Medicine

    Institute of Scientific and Technical Information of China (English)

    陈赛娟; 王一煌

    2011-01-01

    Toll, a protein involved in the dorsoventral development of fruit flies, was first discovered by the German Scientist Chris-tiane Niisslein-Volhard and his colleagues in 1985. In 1996, Jules Hoffmann at the National Center for Scientific Research in Strasbourg, France, discovered that the product of Toll was involved in the sensing of pathogenic infections in fruit flies, and its activation was necessary for the initiation of effective defense; In 1998, Bruce A. Beutler at the Scripps Research Institute discovered that the li-popolysaccharide(LPS, a microbial pathogenic product) resistant mouse had a mutation in the receptor gene very similar to the Toll in fruit flies, and proved the Toll-like receptor was the sensor of LPS. These discoveries showed that mammals and fruit flies adopt the similar molecules to activate innate immunity. Therefore, they shared the half of the 2011 Nobel Prize in Physiology or Medicinefor their discoveries concerning the sensors for the activation of innate immunity. Another half of the prize was awarded to Ralph M. Steinman at the Rockefeller University in New York. In 1973, Steinman discovered the Dendritic cells (DCs) and proved that it could activate the T cells and initiate the adaptive immune response. Further studies showed that the DCs could sense the signals arising from the innate immune response and control the T cell activation. This makes it possible for the immune system to react towards pathogenic microorganisms while avoiding attacks on own body's endogenous molecules. These discoveries provide us further insights into the mechanism of activation and regulation of the immune system, and will facilitate the development of novel methods in disease prevention and treatment.%Toll最早由德国科学家克里斯汀·纽斯兰芙哈(Christiane Nüsslein-Volhard)等于1985年发现,其功能为调控果蝇体节发育.1996年法国斯特拉斯堡国立研究中心的朱尔斯·霍夫曼(Jules Hoffmann)发现Toll基因产物

  13. Discovering plate boundaries: Laboratory and classroom exercises using geodetic data to develop students' understanding of plate motion

    Science.gov (United States)

    Olds, S. E.

    2010-12-01

    available, the Jules Verne Voyager (JVV) interactive map tools are available online and are very well received by educators in introductory Earth science courses. In response to requests for easily accessible and usable data, UNAVCO built the Data for Educators webpage, incorporating an embedded Google Map with GPS locations and providing current GPS time series plots and downloadable data from the Plate Boundary Observatory. To extend and update the datasets available to our community, UNAVCO has developed a GPS velocity viewer using Google Maps technology and provides a learning- focused KMZ combining geophysical data sets for Google-Earth. By combining near real-time geodetic data with modern visualization tools into inquiry-based learning resources, students are deepening their understanding about the active nature of plate margins and gain a solid foundation for learning future concepts. UNAVCO is a non-profit, membership-governed consortium funded by the National Science Foundation and NASA.

  14. Snow drift: acoustic sensors for avalanche warning and research

    Science.gov (United States)

    Lehning, M.; Naaim, F.; Naaim, M.; Brabec, B.; Doorschot, J.; Durand, Y.; Guyomarc'h, G.; Michaux, J.-L.; Zimmerli, M.

    Based on wind tunnel measurements at the CSTB (Jules Verne) facility in Nantes and based on field observations at the SLF experimental site Versuchsfeld Weissfluhjoch, two acoustic wind drift sensors are evaluated against different mechanical snow traps and one optical snow particle counter. The focus of the work is the suitability of the acoustic sensors for applications such as avalanche warning and research. Although the acoustic sensors have not yet reached the accuracy required for typical research applications, they can, however, be useful for snow drift monitoring to help avalanche forecasters. The main problem of the acoustic sensors is a difficult calibration that has to take into account the variable snow properties. Further difficulties arise from snow fall and high wind speeds. However, the sensor is robust and can be operated remotely under harsh conditions. It is emphasized that due to the lack of an accurate reference method for snow drift measurements, all sensors play a role in improving and evaluating snow drift models. Finally, current operational snow drift models and snow drift sensors are compared with respect to their usefulness as an aid for avalanche warning. While drift sensors always make a point measurement, the models are able to give a more representative drift index that is valid for a larger area. Therefore, models have the potential to replace difficult observations such as snow drift in operational applications. Current models on snow drift are either only applicable in flat terrain, are still too complex for an operational application (Lehning et al., 2000b), or offer only limited information on snow drift, such as the SNOWPACK drift index (Lehning et al., 2000a). On the other hand, snow drift is also difficult to measure. While mechanical traps (Mellor 1960; Budd et al., 1966) are probably still the best reference, they require more or less continuous manual operation and are thus not suitable for remote locations or long

  15. UNAVCO Software and Services for Visualization and Exploration of Geoscience Data

    Science.gov (United States)

    Meertens, C.; Wier, S.

    2007-12-01

    UNAVCO has been involved in visualization of geoscience data to support education and research for several years. An early and ongoing service is the Jules Verne Voyager, a web browser applet built on the GMT that displays any area on Earth, with many data set choices, including maps, satellite images, topography, geoid heights, sea-floor ages, strain rates, political boundaries, rivers and lakes, earthquake and volcano locations, focal mechanisms, stress axes, and observed and modeled plate motion and deformation velocity vectors from geodetic measurements around the world. As part of the GEON project, UNAVCO has developed the GEON IDV, a research-level, 4D (earth location, depth and/or altitude, and time), Java application for interactive display and analysis of geoscience data. The GEON IDV is designed to meet the challenge of investigating complex, multi-variate, time-varying, three-dimensional geoscience data anywhere on earth. The GEON IDV supports simultaneous displays of data sets from differing sources, with complete control over colors, time animation, map projection, map area, point of view, and vertical scale. The GEON IDV displays gridded and point data, images, GIS shape files, and several other types of data. The GEON IDV has symbols and displays for GPS velocity vectors, seismic tomography, earthquake focal mechanisms, earthquake locations with magnitude or depth, seismic ray paths in 3D, seismic anisotropy, convection model visualization, earth strain axes and strain field imagery, and high-resolution 3D topographic relief maps. Multiple data sources and display types may appear in one view. As an example of GEON IDV utility, it can display hypocenters under a volcano, a surface geology map of the volcano draped over 3D topographic relief, town locations and political boundaries, and real-time 3D weather radar clouds of volcanic ash in the atmosphere, with time animation. The GEON IDV can drive a GeoWall or other 3D stereo system. IDV output

  16. Earthquakes in Action: Incorporating Multimedia, Internet Resources, Large-scale Seismic Data, and 3-D Visualizations into Innovative Activities and Research Projects for Today's High School Students

    Science.gov (United States)

    Smith-Konter, B.; Jacobs, A.; Lawrence, K.; Kilb, D.

    2006-12-01

    The most effective means of communicating science to today's "high-tech" students is through the use of visually attractive and animated lessons, hands-on activities, and interactive Internet-based exercises. To address these needs, we have developed Earthquakes in Action, a summer high school enrichment course offered through the California State Summer School for Mathematics and Science (COSMOS) Program at the University of California, San Diego. The summer course consists of classroom lectures, lab experiments, and a final research project designed to foster geophysical innovations, technological inquiries, and effective scientific communication (http://topex.ucsd.edu/cosmos/earthquakes). Course content includes lessons on plate tectonics, seismic wave behavior, seismometer construction, fault characteristics, California seismicity, global seismic hazards, earthquake stress triggering, tsunami generation, and geodetic measurements of the Earth's crust. Students are introduced to these topics through lectures-made-fun using a range of multimedia, including computer animations, videos, and interactive 3-D visualizations. These lessons are further enforced through both hands-on lab experiments and computer-based exercises. Lab experiments included building hand-held seismometers, simulating the frictional behavior of faults using bricks and sandpaper, simulating tsunami generation in a mini-wave pool, and using the Internet to collect global earthquake data on a daily basis and map earthquake locations using a large classroom map. Students also use Internet resources like Google Earth and UNAVCO/EarthScope's Jules Verne Voyager Jr. interactive mapping tool to study Earth Science on a global scale. All computer-based exercises and experiments developed for Earthquakes in Action have been distributed to teachers participating in the 2006 Earthquake Education Workshop, hosted by the Visualization Center at Scripps Institution of Oceanography (http

  17. Snow drift: acoustic sensors for avalanche warning and research

    Directory of Open Access Journals (Sweden)

    M. Lehning

    2002-01-01

    Full Text Available Based on wind tunnel measurements at the CSTB (Jules Verne facility in Nantes and based on field observations at the SLF experimental site Versuchsfeld Weissfluhjoch, two acoustic wind drift sensors are evaluated against different mechanical snow traps and one optical snow particle counter. The focus of the work is the suitability of the acoustic sensors for applications such as avalanche warning and research. Although the acoustic sensors have not yet reached the accuracy required for typical research applications, they can, however, be useful for snow drift monitoring to help avalanche forecasters. The main problem of the acoustic sensors is a difficult calibration that has to take into account the variable snow properties. Further difficulties arise from snow fall and high wind speeds. However, the sensor is robust and can be operated remotely under harsh conditions. It is emphasized that due to the lack of an accurate reference method for snow drift measurements, all sensors play a role in improving and evaluating snow drift models. Finally, current operational snow drift models and snow drift sensors are compared with respect to their usefulness as an aid for avalanche warning. While drift sensors always make a point measurement, the models are able to give a more representative drift index that is valid for a larger area. Therefore, models have the potential to replace difficult observations such as snow drift in operational applications. Current models on snow drift are either only applicable in flat terrain, are still too complex for an operational application (Lehning et al., 2000b, or offer only limited information on snow drift, such as the SNOWPACK drift index (Lehning et al., 2000a. On the other hand, snow drift is also difficult to measure. While mechanical traps (Mellor 1960; Budd et al., 1966 are probably still the best reference, they require more or less continuous manual operation and are thus not suitable for remote locations

  18. Plate Boundary Observatory Infrastructure and Data Products in Education and Outreach

    Science.gov (United States)

    Eriksson, S. C.; Barbour, K.; Lee, E.

    2005-12-01

    of young scientists and more established scientists broadening their research interests. In addition, collecting, manipulating, and aggregating real scientific data for classroom use is a current priority in science education. Educators want their students to use these data to draw conclusions following the logical processes characteristic of the scientific endeavor. Hence, PBO is a natural source of data for use in the classroom. Staff and community members are designing higher level data products for a variety of audiences in formal education (students and instructors in middle/high school, community colleges, undergraduate science majors and students in general science education, graduate students) and in informal education (museums, park information centers, science centers, and media. PBO is working on a chapter for the Earth Exploration Toolbox (http://serc.carleton.edu/eet/) for undergraduate general science education, and the Jules Verne Voyager will include a user-friendly interface and associated educational materials. Evaluation of the effectiveness of this entire program and of individual projects and products is a major undertaking. The multitude of tasks, integration of these tasks into a coherent program, and identification of resources for evaluation are both opportunities and challenges in helping build a program with measurable impact.

  19. Benchmarking sensitivity of biophysical processes to leaf area changes in land surface models

    Science.gov (United States)

    Forzieri, Giovanni; Duveiller, Gregory; Georgievski, Goran; Li, Wei; Robestson, Eddy; Kautz, Markus; Lawrence, Peter; Ciais, Philippe; Pongratz, Julia; Sitch, Stephen; Wiltshire, Andy; Arneth, Almut; Cescatti, Alessandro

    2017-04-01

    Land surface models (LSM) are widely applied as supporting tools for policy-relevant assessment of climate change and its impact on terrestrial ecosystems, yet knowledge of their performance skills in representing the sensitivity of biophysical processes to changes in vegetation density is still limited. This is particularly relevant in light of the substantial impacts on regional climate associated with the changes in leaf area index (LAI) following the observed global greening. Benchmarking LSMs on the sensitivity of the simulated processes to vegetation density is essential to reduce their uncertainty and improve the representation of these effects. Here we present a novel benchmark system to assess model capacity in reproducing land surface-atmosphere energy exchanges modulated by vegetation density. Through a collaborative effort of different modeling groups, a consistent set of land surface energy fluxes and LAI dynamics has been generated from multiple LSMs, including JSBACH, JULES, ORCHIDEE, CLM4.5 and LPJ-GUESS. Relationships of interannual variations of modeled surface fluxes to LAI changes have been analyzed at global scale across different climatological gradients and compared with satellite-based products. A set of scoring metrics has been used to assess the overall model performances and a detailed analysis in the climate space has been provided to diagnose possible model errors associated to background conditions. Results have enabled us to identify model-specific strengths and deficiencies. An overall best performing model does not emerge from the analyses. However, the comparison with other models that work better under certain metrics and conditions indicates that improvements are expected to be potentially achievable. A general amplification of the biophysical processes mediated by vegetation is found across the different land surface schemes. Grasslands are characterized by an underestimated year-to-year variability of LAI in cold climates

  20. Bleomycin lung toxicity: who are the patients with increased risk?

    Science.gov (United States)

    Azambuja, E; Fleck, J F; Batista, R G; Menna Barreto, S S

    2005-01-01

    Bleomycin is an antibiotic drug with anticancer properties produced by Streptomyces verticillus [Cheson BD. Pharmacology of cancer chemotherapy: miscellaneous chemotherapeutic agents. In De Vita Jr. VT, Hellmann S, Rosenberg AS, editors. Cancer principles and practice of oncology. Lippincott Willians & Wilkins; 2001. p. 452-459]. It was isolated in 1966 by Umezawa et al. and its mechanism of action is breaking the DNA double helix by the production of free radicals, which is oxygen and iron dependent [Cheson BD. Pharmacology of cancer chemotherapy: miscellaneous chemotherapeutic agents. In De Vita Jr. VT, Hellmann S, Rosenberg AS, editors. Cancer principles and practice of oncology. Lippincott Willians & Wilkins; 2001. p. 452-459; Hay J, Shahzeidi S, Laurent G. Mechanisms of bleomycin-induced lung damage. Arch Toxicol 1991;65:81-94]. Bleomycin may be inactivated by bleomycin hidrolase presents in normal and tumoral cells [Cheson BD. Pharmacology of cancer chemotherapy: miscellaneous chemotherapeutic agents. In De Vita Jr. VT, Hellmann S, Rosenberg AS, editors. Cancer principles and practice of oncology. Lippincott Willians & Wilkins; 2001. p. 452-459; Hay J, Shahzeidi S, Laurent G. Mechanisms of bleomycin-induced lung damage. Arch Toxicol 1991;65:81-94; Jules-Elysee K, White DA. Bleomycin-induced pulmonary toxicity. Clinics Chest Med 1990;11:1-20]. The complex bleomycin-Fe has been the most studied because bleomycin joins the DNA and Fe at the same time, and release of free radicals happens in the presence of molecular oxygen [Hay J, Shahzeidi S, Laurent G. Mechanisms of bleomycin-induced lung damage. Arch Toxicol 1991;65:81-94]. Bleomycin has a renal metabolism with 50% of dose eliminated in 4h after its administration and 70% in the next 24h. Its half-life (T 1/2) is not altered, although the creatinine clearance drops to 25-35 ml/min [Cheson BD. Pharmacology of cancer chemotherapy: miscellaneous chemotherapeutic agents. In De Vita Jr. VT, Hellmann S, Rosenberg

  1. Birmingham Urban Climate Change with Neighbourhood Estimates of Environmental Risk (buccaneer)

    Science.gov (United States)

    Bassett, R.; Thornes, J.; Cai, X.; Rees, R.

    2011-12-01

    The BUCCANEER project is a knowledge transfer partnership between the University of Birmingham and Birmingham City Council to help ensure that the city is prepared for the impacts of climate change. The project will equip service areas such as planners and health protection agencies with the necessary information and tools needed to adapt. UK climate projections indicate a 3.7oC temperature increase for Birmingham, UK by 2080 (medium emissions scenario). The 2003 heat-wave that caused over 2000 deaths in England and Wales will become an average summer by 2040. By the end of the century, the 2003 heat wave will be considered a cool summer. The dense urban fabric of Birmingham, the UK's second largest city, creates a warming effect when compared to surrounding rural areas. Past studies have found the nature of this urban heat island (UHI) to be related to city size, moisture availability, land-use, anthropogenic emissions, building materials and geometry. The UHI effect can lead to heat stress and air pollution problems which are a major health concern. Birmingham's UHI is not currently modelled. More specifically the UK climate projections treat Birmingham as a homogeneous slab of grassland. The inclusions of the urban areas in a climate model will show an intensification of the likely heat risk in future projections. In the present study, the JULES (Joint UK Land Environment Simulator) model has been setup and run for Birmingham and surrounding areas. The UHI was found to be greater than 3.5oC in Birmingham when modelled during heat waves. The model's performance is evaluated against data from two UK Met Office standard sites: Edgbaston (urban) and Winterbourne (rural). The temperatures predicted by the model over a 12 month (2010) simulation show a strong correlation with the observations. The model also reproduces the diurnal UHI intensity averaged over a year reasonably well. The model evaluation is also complemented by a data set of tiny-tag data logger

  2. Flooding from Intense Rainfall: an overview of project SINATRA

    Science.gov (United States)

    Cloke, Hannah

    2014-05-01

    identifying the large-scale atmospheric conditions associated with FFIR events, and linking them to catchment type. (2) Use this new understanding and data to improve models of FFIR so we can predict where they may happen nationwide by: employing an integrated catchment/urban scale modelling approach to FFIR at high spatial and temporal scales, modelling rapid catchment response to flash floods and their impacts in urban areas; scaling up to larger catchments by improving the representation of fast riverine and surface water flooding and hydromorphic change (including debris flow) in regional scale models of FFIR; improving the representation of FFIR in the JULES land surface model by integrating river routing and fast runoff processes, and performing assimilation of soil moisture and river discharge into the model run (3) Use these new findings and predictions to provide the Environment Agency and other professionals with information and software they can use to manage FFIR, reducing their damage and impact to communities by: developing tools to enable prediction of future FFIR impacts to support the Flood Forecasting Centre in issuing new 'impacts-based' warnings about their occurrence; developing a FFIR analysis tool to assess risks associated with rare events in complex situations involving incomplete knowledge, analogous to those developed for safety assessment in radioactive waste management.

  3. The effect of plant water stress approach on the modelled energy-, water and carbon balance for Mediterranean vegetation; implications for (agro)meteorological applications.

    Science.gov (United States)

    Verhoef, Anne; Egea, Gregorio; Garrigues, Sebastien; Vidale, Pier Luigi; Balan Sarojini, Beena

    2017-04-01

    Current land surface schemes in many crop, weather and climate models make use of the coupled photosynthesis-stomatal conductance (A-gs) models of plant function to determine the transpiration flux and gross primary productivity. Vegetation exchange is controlled by many environmental factors, and soil moisture control on root water uptake and stomatal function is a primary pathway for feedbacks in sub-tropical to temperate ecosystems. Representations of the above process of soil moisture control on plant function (often referred to as a 'beta' factor) vary among models. This matters because the simulated energy, water and carbon balances are very sensitive to the representation of water stress in these models. Building on Egea et al. (2011) and Verhoef and Egea (2014), we tested a range of 'beta' approaches in a leaf-level A-gs model (compatible with models such as JULES, CHTESSEL, ISBA, CLM), as well as some beta-approaches borrowed from the agronomic, and plant physiological communities (a combined soil-plant hydraulic approach, see Verhoef and Egea, 2014). Root zone soil moisture was allowed to limit plant function via individual routes (via CO2 assimilation, stomatal conductance, or mesophyll conductance) as well as combinations of that. The simulations were conducted for a typical Mediterranean field site (Avignon, France; Garrigues et al., 2015) which provides 14 years of near-continuous measurements of soil moisture and atmospheric driving data. Daytime (8-16 hrs local time) data between April-September were used. This allowed a broad range of atmospheric and soil moisture/vegetation states to be explored. A number of crops and tree types were investigated in this way. We evaluated the effect of choice of beta-function for Mediterranean climates in relation to stomatal conductance, transpiration, photosynthesis, and leaf surface temperature. We also studied the implications for a range of widely used agro-/micro-meteorological indicators such as Bowen ratio

  4. On the long duration accelerometric signals coming from the International Space Station during the SODI-IVIDIL and SODI-DCMIX2 experiments

    Science.gov (United States)

    Saez, Nuria; Shevtsova, Valentina; Ruiz, Xavier; Simon, M. Jose; Marcos, Rosa; Gavalda, Fina

    . The coefficients of the continuous transform at lower scales represent energy at higher frequencies, while the coefficients at higher scales represent energy at lower frequencies. Obviously, the coefficients depend on the wavelet used, so we have also discussed in each run the best one to extract the information needed. It is important to note finally that HOSA and wavelet techniques are, obviously, not new, but never have been used in the analyses of long accelerometric signals coming from the Station. In this sense, the present techniques can be considered as complementary to the standard ones offered online in the PIMS NASA web actually. [1] Jules, K., McPherson, K., Hrovat, K., and E. Kelly, E., “Initial characterization of the microgravity environment of the international space station: increments 2 through 4”, Acta Astronautica, Vol. 55 No. 10, 2004, pp. 855-887. [2] http://pims.grc.nasa.gov/html/ISSAccelerationArchive.html [3] Sáez, N., Gavaldà, Jna., Ruiz, X., and Shevtsova, V., “Detecting Accelerometric Nonlinearities in the International Space Station.”, American Institute of Aeronautics and Astronautics, AIAA. (Submitted)

  5. How to teach geocomplexity at two opposite levels? The 'Klippen of Cabrières' case study (Hérault, France).

    Science.gov (United States)

    Giusti, Christian

    2014-05-01

    specialties required: inorganic chemistry, paleontology, structural geology, geomorphology. For the public of motivated adults, it may be helpful to remember the key milestones of one century of regional geology: first detailed geological mapping by Paul Gervais de Rouville in the 1870s, Jules Bergeron's "nappe de recouvrement" inspired by the work of Marcel Bertrand in Provence and Switzerland, Bernard Gèze's "nappe-pli couché" derived on Pierre Termier's "nappe du premier genre" in the Alps, the widespread use of sedimentological and micro-tectonic criteria after Second World War (though formerly implemented by André Demay in the Cévennes before 1939), with the studies of Lamoraal Ulbo Sitter, Rodolphe Trümpy and John Rodgers in the 1950s up to those of Maurice Mattauer, François Proust and François Arthaud in the early 1970s. Regarding the teaching of geological time, the issue will be addressed ex situ with the help of the clock model defined above, and could be completed by fieldwork with the observation in situ of one of the real "bars" of the stratigraphic "ladder", i.e. the GSSP's of La Serre section. Two other points are situated nearby: the Coumiac quarry near Cessenon (base of the Famennian Stage) and the Col du Puech de la Suque (base of the Frasnian Stage and Upper Devonian Sub-System). Fieldwork is aimed to link the study of geodiversity to that of biodiversity, in addition to paleontology, paleogeography and the reconstruction of palaeoenvironments.

  6. Nuclear heating measurements by in-pile calorimetry: prospective works for a microsensor design

    Energy Technology Data Exchange (ETDEWEB)

    Reynard-Carette, C.; Carette, M.; Aguir, K.; Bendahan, M.; Fiorido, T. [Aix Marseille Universite, CNRS, Universite de Toulon, IM2NP UMR 7334, 13397, Marseille (France); Lyoussi, A.; Fourmentel, D.; Villard, J.F. [CEA, DEN, DER, Instrumentation Sensors and Dosimetry Laboratory, Cadarache, F-13108 (France); Barthes, M.; Lanzetta, F.; Layes, G.; Vives, S. [FEMTO-ST, UMR 6174, Departement ENERGIE, Universite de Franche-Comte, 90000, Belfort (France)

    2015-07-01

    Since 2009 works have been performed in the framework of joint research programs between CEA and Aix-Marseille University. The main aim of these programs is to design and develop in-pile instrumentations, advanced calibration procedure and accurate measurement methods in particular for the new Material Testing Reactor (MTR) under construction in the South of France: Jules Horowitz Reactor (JHR). One major sensor is a specific radiometric calorimeter, which was studied out-of-pile from a thermal point of view and in-pile during irradiation campaigns. This sensor type is dedicated to measurements of nuclear heating (energy deposition rate per mass unit induced by interactions between nuclear rays and matter) inside experimental channels of MTRs. This kind of in-pile calorimeter corresponds to heat flux calorimeter exchanging with the external cooling fluid. This thermal running mode allows the establishment of steady thermal conditions inside the sensor to carry out online continuous measurements inside the reactor (core or reflector). Two main types of calorimeters exist. The first type consists of a single cell calorimeter. It is divided into a sample of material to be tested and a jacket instrumented with two thermocouples or a single thermocouple (Gamma Thermometer). The second, called a differential calorimeter, is composed of two superposed twin cells (a measurement cell containing a sample of material, and a reference cell to remove the heating of the cell body) instrumented with four thermocouples and two electrical heaters. Contrary to a single-cell calorimeter, a differential calorimeter allows the compensation of the parasite nuclear heating of the sensor body or jacket. Moreover, it possesses interesting advantages: thanks to the heaters embedded in the cells, three different measurement methods can be applied during irradiations to quantify nuclear heating. The first one is based on the use of out-of-pile calibration curves obtained by generating a heat

  7. Fuel moisture content estimation: a land-surface modelling approach applied to African savannas

    Science.gov (United States)

    Ghent, D.; Spessa, A.; Kaduk, J.; Balzter, H.

    2009-04-01

    Despite the importance of fire to the global climate system, in terms of emissions from biomass burning, ecosystem structure and function, and changes to surface albedo, current land-surface models do not adequately estimate key variables affecting fire ignition and propagation. Fuel moisture content (FMC) is considered one of the most important of these variables (Chuvieco et al., 2004). Biophysical models, with appropriate plant functional type parameterisations, are the most viable option to adequately predict FMC over continental scales at high temporal resolution. However, the complexity of plant-water interactions, and the variability associated with short-term climate changes, means it is one of the most difficult fire variables to quantify and predict. Our work attempts to resolve this issue using a combination of satellite data and biophysical modelling applied to Africa. The approach we take is to represent live FMC as a surface dryness index; expressed as the ratio between the Normalised Difference Vegetation Index (NDVI) and land-surface temperature (LST). It has been argued in previous studies (Sandholt et al., 2002; Snyder et al., 2006), that this ratio displays a statistically stronger correlation to FMC than either of the variables, considered separately. In this study, simulated FMC is constrained through the assimilation of remotely sensed LST and NDVI data into the land-surface model JULES (Joint-UK Land Environment Simulator). Previous modelling studies of fire activity in Africa savannas, such as Lehsten et al. (2008), have reported significant levels of uncertainty associated with the simulations. This uncertainty is important because African savannas are among some of the most frequently burnt ecosystems and are a major source of greenhouse trace gases and aerosol emissions (Scholes et al., 1996). Furthermore, regional climate model studies indicate that many parts of the African savannas will experience drier and warmer conditions in future

  8. Visual migraine aura with or without headache: association with right to left shunt and assessment following transcutaneous closure

    Directory of Open Access Journals (Sweden)

    Mojadidi MK

    2012-07-01

    Full Text Available M Khalid Mojadidi,1 Hamidreza Khessali,1 Rubine Gevorgyan,1 Ralph D Levinson,2 Jonathan M Tobis11Division of Interventional Cardiology, David Geffen School of Medicine, University of California at Los Angeles, 2Division of Comprehensive Ophthalmology and Ocular Inflammatory Disease Center, Jules Stein Eye Institute, University of California at Los Angeles, Los Angeles, CA, USABackground: Right to left shunting, usually caused by a patent foramen ovale (PFO, is associated with migraine and visual aura. It is unknown if patients who present with visual aura without headache behave similarly to those experiencing typical migraine headache with aura. The purpose of this study was to assess the prevalence of right to left shunting in patients who present with migraine aura without headache and evaluate the response to PFO closure.Methods: The records of patients referred to the Interventional Cardiology program at the University of California at Los Angeles for suspected intracardiac right to left shunt were reviewed. Individuals with visual auras with or without migraine headaches were divided into three groups: group A (aura + migraine, migraine aura during or within 60 minutes of headache; group B (migraine aura unrelated to headache, migraine aura and headache temporally unrelated; and group C (migraine aura only, isolated migraine visual aura without a history of headaches. The presence of right to left shunt was assessed using transcranial Doppler with an agitated saline test. PFO closure was performed in 80 patients. Residual headache and migraine visual aura were assessed 3 and 12 months after the procedure. The control group consisted of 200 patients referred for diagnostic cardiac catheterization.Results: Of 590 referred patients, 225 had migraine visual aura with or without headache. The prevalence of right to left shunt was similar (P = 0.66 in groups B (21/29, 72% and C (14/21, 67%. Group A patients had a higher prevalence of right to

  9. Evolution of the Foucault-Secretan reflecting telescope

    Science.gov (United States)

    Tobin, William

    2016-08-01

    his cousin Georges Secretan. Production of silvered-glass reflectors and other scientific instruments languished, and focal ratios slowed. Production appears to have revived after R. Mailhat became Director of the company's workshops and then founded his own firm. In 1903 the Secretan Company offered a simplified 125-mm reflector designed specially for members of the Société Astronomique de France, perhaps promoted by Georges' son Paul. Foucault-style reflecting telescopes were offered by other makers too, including Jules Duboscq, Édouard Lutz and Albert Bardou. Following Georges' death in 1906 the Company was operated by Paul before being sold to Charles Épry in 1906 who associated with Gustave Jacquelin in 1913. Only 125- to 200-mm amateur reflectors were offered in their 1924 and 1942 catalogues. Non-specific advertisements for reflectors continued beyond amalgamation with the Morin Company in 1963, but disappeared after a subsequent merger with the Société de Recherches et de Perfectionnements Industriels c.1967.

  10. Towards UKESM: Recent developments in the representation of aerosols using the GLOMAP-Mode aerosol scheme

    Science.gov (United States)

    Mulcahy, Jane; Johnson, Colin; Mann, Graham W.; Woodward, Stephanie; Johnson, Ben T.; Jones, Andy; Sellar, Alistair; Dalvi, Mohit; Carslaw, Ken S.; Jones, Colin

    2014-05-01

    to its predecessor CLASSIC are also presented and discussed. This work is distributed under the Creative Commons Attribution 3.0 Unported License together with an author copyright. This license does not conflict with the regulations of the Crown Copyright. References: 1. Walters et al. (2013) The Met Office Unified Model Global Atmosphere 4.0 and JULES Global Land 4.0 configurations, Geosci. Model Dev. Discuss., 6, 2813-2881. 2. Carslaw et al. (2010) A review of natural aerosol interactions and feedbacks within the Earth system, Atmos. Chem. Phys., 10, 1701-1737, doi:10.5194/acp-10-1701-2010. 3. Mann et al. (2010) Description and evaluation of GLOMAP-mode: a modal global aerosol microphysics model for the UKCA composition-climate model, Geosci. Model Dev., 3, 519-551, doi:10.5194/gmd-3-519-2010. 4. Telford et al. (2014) Evaluation of the UM-UKCA model configuration for Chemistry of the Stratosphere and Troposphere (CheST), Geosci. Model Dev., In preparation, 2014.

  11. Folklore et écriture vernaculaire dans The Autobiography of Miss Jane Pittman

    Directory of Open Access Journals (Sweden)

    Laurence Cossu-Beaumont

    2006-05-01

    , ainsi que l’illustre le drame de Tee Bob et Mary Agnes, et surtout le récit à deux voix qu’en font Jane et Jules Raynard (« speculatin » p. 205.

  12. Figures and Institutions of the neurological sciences in Paris from 1800 to 1950. Part IV: Psychiatry and psychology.

    Science.gov (United States)

    Poirier, J; Clarac, F; Barbara, J-G; Broussolle, E

    2012-05-01

    We present a short historical review on the major institutions and figures who contributed to make Paris a renowned centre of physiology and neurology during the XIXth and the first half of the XXth century. We purposely chose to focus on the period 1800-1950, as 1800 corresponds to the actual beginning of neurosciences, and as 1950 marks their exponential rise. Our presentation is divided into four chapters, matching the main disciplines that have progressed and contributed most to the knowledge we have of the brain sciences: anatomy, physiology, neurology, and psychiatry-psychology. The present article is the fourth of the four parts of this review, which deals with the chapter on psychiatry and psychology. When the French Revolution occurred, only a few institutions were taking care of the mentally ill. In the Paris area, these included Maison Royale de Charenton, Les Petites Maisons, and one of the departments of larger hospitals such as Hôtel-Dieu, the Salpêtrière Hospital and Bicêtre Hospital. One of the founders of psychiatry in Paris at that time and thereafter was Philippe Pinel (1745-1826) who was the first to distinguish insane/alienated patients from misfits, beggars, and other vagabonds. During the first half of the XIXth century, his student Jean-Étienne Esquirol (1772-1840) also played a major role with his treatise on mental diseases and the 1838 law and the creation of asylums in all parts of France. Alienists were in general caregivers and learned by themselves. In contrast, at the academic level, the emerging disciplines psychiatry and neurology were very close to each other in the second half of the XIXth century, the best example being Jules Baillarger (1809-1890). The actual development of psychiatry and psychology and the foundation of psychoanalysis later in the XIXth century and in the first half of the XXth century owed much to several European doctors and scientists, particularly those from British institutions and from German

  13. Monte-Carlo Simulations of the Nuclear Energy Deposition Inside the CARMEN-1P Differential Calorimeter Irradiated into OSIRIS Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Amharrak, H.; Reynard-Carette, C.; Carette, M. [Aix Marseille Universite, CNRS, Universite de Toulon, IM2NP UMR 7334, 13397, Marseille (France); Lemaire, M.; Vaglio-Gaudard, C. [CEA, DEN, DER, SPRC, LPN, Cadarache, F-13108 Saint Paul Lez Durance (France); Fourmentel, D.; Lyoussi, A. [CEA, DEN, Departement d' Etudes des Reacteurs, Service de Physique Experimentale, Laboratoire Dosimetrie Capteurs Instrumentation, 13108 Saint-Paul-lez-Durance (France)

    2015-07-01

    The nuclear heating measurements in Material Testing Reactors (MTRs) are crucial for the study of nuclear materials and fuels under irradiation. The reference measurements of this nuclear heating are especially performed by a differential calorimeter including a graphite sample material. These measurements are then used for other experimental conditions in order to predict the nuclear heating and thermal conditions induced in the irradiation devices. Nuclear heating is a great deal of interest at the moment as the measurement of such heating is an important issue for MTRs reactors. This need is especially generated by the new Jules Horowitz Reactor (JHR), under construction at CEA/Cadarache 'French Alternative Energies and Atomic Energy Commission'. This new reactor, that will be operational in late 2019, is a new facility for the nuclear research on materials and fuels. Indeed the expected nuclear heating rate is about 20 W/g for nominal capacity of 100 MW. The present Monte Carlo calculation works belong to the IN-CORE (Instrumentation for Nuclear radiation and Calorimetry On line in Reactor): a joint research program between the CEA and Aix- Marseille University in 2009. One scientific aim of this program is to design and develop a multi-sensors device, called CARMEN, dedicated to the measurements of main physical parameters simultaneously encountered inside JHR's experimental channels (core and reflector) such as neutron fluxes, photon fluxes, temperature, and nuclear heating. A first prototype was already developed. This prototype includes two mock-ups dedicated respectively to neutronic measurements (CARMEN-1N) and to photonic measurements (CARMEN-1P) with in particular a specific differential calorimeter. Two irradiation campaigns were performed successfully in the periphery of OSIRIS reactor (a MTR located at Saclay, France) in 2012 for nuclear heating levels up to 2 W/g. First Monte Carlo calculations reduced to the graphite sample of the

  14. Study of the influence of heat sources on the out-of-pile calibration curve of calorimetric cells used for nuclear energy deposition quantification

    Energy Technology Data Exchange (ETDEWEB)

    De Vita, C.; Brun, J.; Reynard-Carette, C.; Carette, M.; Amharrak, H. [Aix Marseille Universite, CNRS, Universite de Toulon, IM2NP UMR 7334, 13397, Marseille (France); Lyoussi, A.; Fourmentel, D.; Villard, J.F. [CEA, DEN, DER, Instrumentation Sensors and Dosimetry Laboratory, Cadarache, F-13108 Saint Paul Lez Durance (France)

    2015-07-01

    At present the Jules Horowitz Reactor is under construction in Cadarache research center of CEA 'French Alternative Energies and Atomic Energy Commission' center located in the south-east of France. This new Material Testing Reactor (MTR) will be operational in late 2019 and will allow the generation of a new experimental potential (up to 20 irradiation devices simultaneously) and new harsh conditions such as higher neutron fluxes (5.10{sup 14} n.cm{sup -2}.s{sup -1} for E≥1 MeV), faster material ageing and higher nuclear heating (up to 20 W/g for nominal capacity of 100 MW). In nuclear research field, the control and the measurement of the nuclear heating (energy deposition rate per mass unit induced by the interactions of radiations with matter) is crucial to carry out accurate studies on ageing of materials and on the behavior of nuclear fuels under irradiation. Several experiments need to know precisely this key parameter in order to establish dedicated thermal conditions. The measurement of the nuclear heating inside MTRs is realized by three kinds of sensors: single-cell calorimeter, differential calorimeter and gamma thermometer. One scientific objective of the IN-CORE program, between CEA and Aix-Marseille University in 2009, is to improve the nuclear heating measurement. In this context a new multi-sensor device, called CARMEN, was made. This device contains in particular a differential calorimeter which was designed to measure the nuclear heating in the periphery of OSIRIS reactor (a MTR located at Saclay, France) up to 2 W/g and tested during two irradiation campaigns. Results obtained during these campaigns showed that temperatures reached inside the calorimeter are higher than ones obtained during the preliminary out-of-pile calibration experiments. For instance for 1.74 W/g, the in-pile temperature of the calorimeter rod is equal to 305 deg. C against 225 deg. C in laboratory conditions by simulating the nuclear heating by Joule Effect

  15. Advanced instrumentation and analysis methods for in-pile thermal and nuclear measurements: from out-of-pile studies to irradiation campaigns

    Energy Technology Data Exchange (ETDEWEB)

    Reynard-Carette, C. [Aix Marseille Universite, CNRS, Universite de Toulon, IM2NP UMR 7334, 13397, Marseille (France); Lyoussi, A. [CEA, DEN, DER, Instrumentation Sensors and Dosimetry Laboratory, Cadarache, F-13108 (France)

    2015-07-01

    Research and development on nuclear fuel behavior under irradiations and accelerated ageing of structure materials is a key issue for sustainable nuclear energy in order to meet specific needs by keeping the best level of safety. A new Material Testing Reactor (MTR), the Jules Horowitz Reactor (JHR) currently under construction in the South of France in the CEA Cadarache research centre will offer a real opportunity to perform R and D programs and hence will crucially contribute to the selection, optimization and qualification of innovative materials and fuels. To perform such programs advanced accurate and innovative experiments, irradiation devices that contain material and fuel samples are required to be set up inside or beside the reactor core. These experiments needs beforehand in situ and on line sophisticated measurements to accurately reach specific and determining parameters such as thermal and fast neutron fluxes, nuclear heating and temperature conditions to precisely monitor and control the conducted assays. Consequently, since 2009 CEA and Aix-Marseille University collaborate in order to design and develop a new multi-sensor device which will be dedicated to measuring profiles of such conditions inside the experimental channels of the JHR. These works are performed in the framework of two complementary joint research programs called MAHRI-BETHY and INCORE. These programs couple experimental studies carried out both out-of nuclear fluxes (in laboratory) and under irradiation conditions (in OSIRIS MTR reactor in France and MARIA MTR reactor in Poland) with numerical works realized by thermal simulations (CAST3M code) and Monte Carlo simulations (MCNP code). These programs deal with three main aims. The first one corresponds to the design and/or the test of new in-pile instrumentation. The second one concerns the development of advanced calibration procedures in particular in the case of one specific sensor: a differential calorimeter used to quantify

  16. Ajouts, omissions, substitutions : la main fautive des copistes dans le texte de L’Éducation sentimentale

    Directory of Open Access Journals (Sweden)

    Déborah Boltz

    2009-01-01

    Full Text Available « Fini ! mon vieux ! Oui, mon bouquin est fini […] Je suis à ma table depuis hier, huit heures du matin. La tête me pète. N’importe, j’ai un fier poids de moins sur l’estomac ». On a reconnu le billet, resté célèbre, où Flaubert annonce à Jules Duplan la fin de son roman qu’il a mis près de cinq ans à rédiger. Or, le 16 mai 1869, date du billet, Flaubert n’en a pas tout à fait fini avec son « bouquin » comme le montre l’intense travail de relecture et de correction accompli pendant les mois qui vont suivre. Après avoir passé une bonne semaine à « recaler » son manuscrit (du 16 au 24 mai, il le donne à recopier et c’est cette « mise au propre », soigneusement calligraphiée, qui servira aux typographes compositeurs pour la fabrication des épreuves. C’est aussi cette copie que Flaubert communique à quelques proches notamment à Maxime Du Camp qui rédige à ce sujet douze pages d’observations…Et enfin, c’est sur cette copie que Flaubert compte bien revoir son texte « phrase par phrase » avec Louis Bouilhet. Mais Bouilhet meurt prématurément fin juillet et c’est seul que Flaubert effectue les dernières corrections du texte de L’Éducation sentimentale. La période de relecture et de correction de la copie dure une quinzaine de jours, au terme de laquelle, l’écrivain remet le manuscrit remanié à son éditeur (le 14 août 1869. La copie des copistes – nous avons pu relever près de quatre graphies différentes - n’a fait, à ce jour, l’objet d’aucune étude critique. Pourquoi ? Sans doute parce que l’activité même de « recopie » a toujours été considérée comme négligeable, anodine, ne pouvant révéler rien d’intéressant, le manuscrit des copistes n’étant en principe que la reproduction servile du Manuscrit définitif autographe… Or il n’en est rien, et ce manuscrit constitue bien un document de genèse irremplaçable, d’autant plus essentiel

  17. 建鲤基因组中一个ty3-gypsy反转录转座子的发现与分析%Isolation and analysis of aty3-gypsy retrotransposon from the genome ofCyprinus carpio var.jian

    Institute of Scientific and Technical Information of China (English)

    丁炜东; 曹丽萍; 曹哲明; 邴旭文

    2016-01-01

    among several genomes is an essential condition to study their dynamics and to better understand their role in species evolution. Long terminal repeat (LTR)-retrotransposons have been reported in diverse eukaryote species, indicating a ubiquitous distribution. Among retrotransposons, the transposable element (TE) class, which are specific to eukaryotes, transpose via an RNA intermediate. Based on their structure, LTR-retrotransposons have been divided into two classes: ty3-gypsy and ty1-copia. In previous research, we found a ty3-gypsy-like retrotransposon, named JRE, in the genome of Jian carp,Cyprinus carpio var.jian. To investigate the function of JRE in the genome of Jian carp, PCR amplification, fluorescence quantitative PCR and fluorescent in situ hybridization were used to explore the structure and characteristics of JRE retrotransposon. Multiple alignments of DNA and protein sequences were constructed using MEGA 5.0 software and were manually curated using BioEdit. Pairwise distances were estimated using the option pairwise deletion of gaps in MEGA5.0. The full-length JRE retrotransposon is 5126 bp, which includes two LTRs of 470 bp at the 5¢ end and 453 bp at the 3¢ end, and two open reading frames (ORFs) between them. One ORF of 4203 bp encodes the group-specific antigen (GAG) and polyprotein (POL). The pol gene has a typical Ty3/gypsy retrotranspo-son structure, and the gene order is protease, reverse transcriptase, RNase H, and integrase (PR–RT–RH–IN). A phy-logenetic analysis of the pol gene showed that it has similarities of 40.7%, 40%, 32.8%, and 30.1% to retrotransposons of the Yesso scallop, Farrer’s scallop, a Great Barrier Reef sponge, and the spot swordtail fish, respectively. Therefore, JRE might belong to the JULE retrotransposon family. The copy number of the JRE retrotransposon in the genome of the Jian carp is 124, as determined by real-time quantitative PCR. The mRNA of the JRE retrotransposon is expressed in five Jian carp tissues

  18. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1993-01-01

    . xvii + 267 pp. -William Roseberry, Rosalie Schwartz, Lawless liberators, political banditry and Cuban independence. Durham NC: Duke University Press, 1989. x + 297 pp. -Robert L. Paquette, Robert M. Levine, Cuba in the 1850's: Through the lens of Charles DeForest Fredricks. Tampa: University of South Florida Press, 1990. xv + 86 pp. -José Sánchez-Boudy, Gustavo Pérez Firmat, The Cuban condition: Translation and identity in modern Cuban literature. Cambridge: Cambridge University Press, 1989. viii + 185 pp. -Dick Parker, Jules R. Benjamin, The United States and the origins of the Cuban revolution: An empire of liberty in an age of national liberation. Princeton: Princeton University Press, 1990. xi + 235 pp. -George Irvin, Andrew Zimbalist ,The Cuban economy: Measurement and analysis of socialist performance. Baltimore: John Hopkins University Press, 1989. xiv + 220 pp., Claes Brundenius (eds -Menno Vellinga, Frank T. Fitzgerald, Managing socialism: From old Cadres to new professionals in revolutionary Cuba. New York: Praeger, 1990. xiv + 161 pp. -Patricia R. Pessar, Eugenia Georges, The making of a transnational community: Migration, development, and cultural change in the Dominican republic. New York: Columbia University Press, 1990. xi + 270 pp. -Lucía Désir, Maria Dolores Hajosy Benedetti, Earth and spirit: Healing lore and more from Puerto Rico. Maplewood NJ: Waterfront Press, 1989. xvii + 245 pp. -Thomas J. Spinner, Jr., Percy C. Hintzen, The costs of regime survival: Racial mobilization, elite domination and control of the state in Guyana and Trinidad. Cambridge: Cambridge University Press, 1989. x + 240 pp. -Judith Johnson, Morton Klass, Singing with the Sai Baba: The politics of revitalization in Trinidad. Boulder CO: Westview, 1991. xvi + 187 pp. -Aisha Khan, Selwyn Ryan, The Muslimeen grab for power: Race, religion and revolution in Trinidad and Tobago. Port of Spain: Inprint Caribbean, 1991. vii + 345 pp. -Drexel G. Woodson, Patrick Bellegarde

  19. Supermagnetic Neutron Star Surprises Scientists, Forces Revision of Theories

    Science.gov (United States)

    2006-08-01

    magnetars because their magnetic fields are 100-1,000 times stronger than those of typical pulsars. It is the decay of those incredibly strong fields that powers their strange X-ray emission. "The magnetic field from a magnetar would make an aircraft carrier spin around and point north quicker than a compass needle moves on Earth," said David Helfand, of Columbia University. A magnetar's field is 1,000 trillion times stronger than Earth's, Helfand pointed out. The new object -- named XTE J1810-197 -- was first discovered by NASA's Rossi X-ray Timing Explorer when it emitted a strong burst of X-rays in 2003. While the X-rays were fading in 2004, Jules Halpern of Columbia University and collaborators identified the magnetar as a radio-wave emitter using the National Science Foundation's (NSF) Very Large Array (VLA) radio telescope in New Mexico. Any radio emission is highly unusual for a magnetar. Because magnetars had not been seen to regularly emit radio waves, the scientists presumed that the radio emission was caused by a cloud of particles thrown off the neutron star at the time of its X-ray outburst, an idea they soon would realize was wrong. With knowledge that the magnetar emitted some form of radio waves, Camilo and his colleagues observed it with the Parkes radio telescope in Australia in March and immediately detected astonishingly strong radio pulsations every 5.5 seconds, corresponding to the previously-determined rotation rate of the neutron star. As they continued to observe XTE J1810-197, the scientists got more surprises. Whereas most pulsars become weaker at higher radio frequencies, XTE J1810-197 does not, remaining a strong emitter at frequencies up to 140 GHz, the highest frequency ever detected from a radio pulsar. In addition, unlike normal pulsars, the object's radio emission fluctuates in strength from day to day, and the shape of the pulsations changes as well. These variations likely indicate that the magnetic fields around the pulsar are changing

  20. Methodology comparison for gamma-heating calculations in material-testing reactors

    Energy Technology Data Exchange (ETDEWEB)

    Lemaire, M.; Vaglio-Gaudard, C.; Lyoussi, A. [CEA, DEN, DER, Cadarache F-13108 Saint Paul les Durance (France); Reynard-Carette, C. [Aix Marseille Universite, CNRS, Universite de Toulon, IM2NP UMR 7334, 13397, Marseille (France)

    2015-07-01

    The Jules Horowitz Reactor (JHR) is a Material-Testing Reactor (MTR) under construction in the south of France at CEA Cadarache (French Alternative Energies and Atomic Energy Commission). It will typically host about 20 simultaneous irradiation experiments in the core and in the beryllium reflector. These experiments will help us better understand the complex phenomena occurring during the accelerated ageing of materials and the irradiation of nuclear fuels. Gamma heating, i.e. photon energy deposition, is mainly responsible for temperature rise in non-fuelled zones of nuclear reactors, including JHR internal structures and irradiation devices. As temperature is a key parameter for physical models describing the behavior of material, accurate control of temperature, and hence gamma heating, is required in irradiation devices and samples in order to perform an advanced suitable analysis of future experimental results. From a broader point of view, JHR global attractiveness as a MTR depends on its ability to monitor experimental parameters with high accuracy, including gamma heating. Strict control of temperature levels is also necessary in terms of safety. As JHR structures are warmed up by gamma heating, they must be appropriately cooled down to prevent creep deformation or melting. Cooling-power sizing is based on calculated levels of gamma heating in the JHR. Due to these safety concerns, accurate calculation of gamma heating with well-controlled bias and associated uncertainty as low as possible is all the more important. There are two main kinds of calculation bias: bias coming from nuclear data on the one hand and bias coming from physical approximations assumed by computer codes and by general calculation route on the other hand. The former must be determined by comparison between calculation and experimental data; the latter by calculation comparisons between codes and between methodologies. In this presentation, we focus on this latter kind of bias. Nuclear

  1. Book Reviews

    Directory of Open Access Journals (Sweden)

    C. Salmon

    1987-10-01

    hukum bagi rakyat di Indonesia, Ph.D thesis Airlangga University, Surabaya: Airlangga University Press, 1985, xviii + 308 pp. - J.M.C. Pragt, Volker Moeller, Javanische bronzen, Staatliche Museen Preussischer Kulturbesitz, Museum für Indische Kunst, Berlin, 1985. Bilderheft 51. 62 pp., ill. - J.J. Ras, Friedrich Seltmann, Die Kalang. Eine Volksgruppe auf Java und ihre Stamm-Myth. Ein beitrag zur kulturgeschichte Javas, Stuttgart: Franz Steiner Verlag Wiesbaden GmbH, 1987, 430 pp. - R. Roolvink, Russell Jones, Hikayat Sultan Ibrahim ibn Adham, Berkeley: Center for South and Southeast Asia Studies, University of California, Monograph Series no. 57, 1985. ix, 332 pp. - R. Roolvink, Russell Jones, Hikayat Sultan Ibrahim, Dordrecht/Cinnaminson: Foris, KITLV, Bibliotheca Indonesica vol. 24, 1983. 75 pp. - Wim Rutgers, Harry Theirlynck, Van Maria tot Rosy: Over Antilliaanse literatuur, Antillen Working Papers 11, Caraïbische Afdeling, Koninklijk Instituut voor Taal-, Land- en Volkenkunde, Leiden, 1986, 107 pp. - C. Salmon, John R. Clammer, ‘Studies in Chinese folk religion in Singapore and Malaysia’, Contributions to Southeast Asian Ethnography no. 2, Singapore, August 1983, 178 pp. - C. Salmon, Ingo Wandelt, Wihara Kencana - Zur chinesischen Heilkunde in Jakarta, unter Mitarbeit bei der Feldforschung und Texttranskription von Hwie-Ing Harsono [The Wihara Kencana and Chinese Therapeutics in Jakarta, with the cooperation of Hwie-Ing Harsono for the fieldwork and text transcriptions], Kölner ethopgraphische Studien Bd. 10, Berlin: Dietrich Reimer Verlag, 1985, 155 pp., 1 plate. - Mathieu Schoffeleers, 100 jaar fraters op de Nederlandse Antillen, Zutphen: De Walburg Pers, 1986, 191 pp. - Mathieu Schoffeleers, Jules de Palm, Kinderen van de fraters, Amsterdam: De Bezige Bij, 1986, 199 pp. - Henk Schulte Nordholt, H. von Saher, Emanuel Rodenburg, of wat er op het eiland Bali geschiedde toen de eerste Nederlanders daar in 1597 voet aan wal zetten. De Walburg Pers

  2. Influencia de la Medicina Francesa en Colombia

    Directory of Open Access Journals (Sweden)

    Ernesto Andrade Valderrama

    1991-12-01

    medicina. Hacia la mitad del siglo aparece el Tratado de Anatomía Patológica, del gran médico alemán: Rudolf Virchow.

    La segunda mentalidad: Fisiopatológica, con una concepción dinámica y procesal de la enfermedad, fué iniciada en Alemania, pero tuvo en Francia su gran propulsor: Claude Bernard, quien en 1865 decía: “Considero el hospital como el vestíbulo de la medicina, como el primer campo de observación médica, pero el verdadero’ santuario de la ciencia médica es el laboratorio” .

    Franceses distinguidos, seguidores de este método, fueron entre otros Etienne-Jules Marey, inventor del esfigmógrafo, precursor del futuro electrocardiógrafo. Achard y Castaigne, precursores con Vaquez de pruebas para el estudio de las pruebas funcionales.

    Al progreso de esta mentalidad, se anexa la fisiología patológica. Aquí fue fundamental el trabajo de Francois Magendie, que figuraría al lado de las dos grandes figuras alemanas: Ludwing Traube y F. Cohnheim y a quien habría de suceder Claude Bernard, quien con su trabajo sobre el Curare y otros experimentos lo llevaría a merecer, ya al comienzo de este siglo, uno de los primeros premios Nobel.

    La tercera mentalidad, definitiva, en la preparación de la medicina para el siglo XX, conocida como mentalidad etiopatológica, gira toda alrededor de la figura cumbre de Louis Pasteur: hizo posible la antisepsia, la patología bacteriológica y la profilaxis de las enfermedades infecciosas.

    Entre los clinicos que habrían de influir en la formación de nuestros especialistas, figuró el dermatólogo Jean Louis Albert, quien desde el Hospital Sto Louis fue el iniciador de la Dermatología Moderna. Otros notables, entre ellos, Devergy, quien fundó el famoso Museo de San Luis. L. Salpetri~re, J.M. Charest, Hospital de Arte, Van Gogh.

    La cirugía, tuvo en Francia el centro de influencia sobre el resto de Europa gracias a la tradición, que arrancó con Ambrosio Paré y que con Dessault