WorldWideScience

Sample records for js mattson jr

  1. Express.js blueprints

    CERN Document Server

    Augarten, Ben; Lin, Eric; Shaikh, Aidha; Soriani, Fabiano Pereira; Tisserand, Geoffrey; Zhang, Chiqing; Zhang, Kan

    2015-01-01

    This book is for beginners to Node.js and also for those who are technically advanced. By the end of this book, every competent developer will have achieved expertise in building web applications with Express.js.

  2. Professional AngularJS

    CERN Document Server

    Karpov, Valeri

    2015-01-01

    A comprehensive guide to AngularJS, Google's open-source client-side framework for app development. Most of the existing guides to AngularJS struggle to provide simple and understandable explanations for more advanced concepts. As a result, some developers who understand all the basic concepts of AngularJS struggle when it comes to building more complex real-world applications. Professional AngularJS provides a thorough understanding of AngularJS, covering everything from basic concepts, such as directives and data binding, to more advanced concepts like transclusion, build systems, and auto

  3. Instant Zepto.js

    CERN Document Server

    Pointer, Ian

    2013-01-01

    A simple starter guide that will walk you through Zepto.js from installation to more advanced topics using a step-by-step approach with useful examples included along the way.Instant Zepto.js is designed for web developers with some jQuery experience who are interested in speeding up and enhancing their web applications, especially on mobile devices.

  4. Mastering Ext JS

    CERN Document Server

    Groner, Loiane

    2013-01-01

    Designed to be a structured guide, Mastering Ext JS is full of engaging examples to help you learn in a practical context.This book is for developers who are familiar with using Ext JS who want to augment their skills to create even better web applications.

  5. Learning Ext JS

    CERN Document Server

    Méndez, Carlos A; Gonzalez, Armando

    2015-01-01

    If you are a JavaScript developer who now wants to use the Ext JS framework, this is the book for you. This guide is useful to you whether you're new to Ext JS 5 or are a seasoned expert. Experience in HTML, CSS, and JavaScript is required in order to understand and get the most out of this book.

  6. Learning Less.js

    CERN Document Server

    Libby, Alex

    2014-01-01

    If you are a designer or developer who wants to quickly learn how to harness the power of Less.js to write more efficient CSS styles that can be applied to a website of any size, then this book is for you. This book will help you master both the basic functions and advanced features of Less.js. It would be helpful to have some familiarity of writing CSS styles, although no prior experience of using CSS preprocessors is required.

  7. SymJS

    DEFF Research Database (Denmark)

    Andreasen, Esben; Li, Guodong; Ghosh, Indradeep

    2014-01-01

    We present SymJS, a comprehensive framework for automatic testing of client-side JavaScript Web applications. The tool contains a symbolic execution engine for JavaScript, and an automatic event explorer for Web pages. Without any user intervention, SymJS can automatically discover and explore Web...... events, symbolically execute the associated JavaScript code, refine the execution based on dynamic feedbacks, and produce test cases with high coverage. The symbolic engine contains a symbolic virtual machine, a string-numeric solver, and a symbolic executable DOM model. SymJS’s innovations include...... a novel symbolic virtual machine for JavaScript Web, symbolic+dynamic feedback directed event space exploration, and dynamic taint analysis for enhancing event sequence construction. We illustrate the effectiveness of SymJS on standard JavaScript benchmarks and various real-life Web applications...

  8. Mastering Ext JS

    CERN Document Server

    Groner, Loiane

    2015-01-01

    If you are a developer who is familiar with Ext JS and want to augment your skills to create even better web applications, this is the book for you. Basic knowledge of JavaScript/HTML/CSS and any server-side language (PHP, Java, C#, Ruby, or Python) is required.

  9. KnockoutJS blueprints

    CERN Document Server

    Russo, Carlo

    2015-01-01

    If you are a JavaScript developer and already know the basics of KnockoutJS and you want to get the most out of it, then this book is for you. This book will help in your transition from a small site to a large web application that is easily maintainable.

  10. Deploying Node.js

    CERN Document Server

    Pasquali, Sandro

    2015-01-01

    If you are an intermediate or advanced developer deploying your Node.js applications, then this book is for you. If you have already built a Node application or module and want to take your knowledge to the next level, this book will help you find your way.

  11. Ext JS 4 First Look

    CERN Document Server

    Groner, Loiane

    2012-01-01

    This book is a practical step-by-step tutorial which guides you to migrate from Ext JS 3 to Ext JS 4. There are examples backed with explanations and plenty of code and illustrations to look forward to. This book is written for web developers who are familiar with Ext JS 3 and want to have detailed insights into the new features of Ext JS 4.

  12. AngularJS directives

    CERN Document Server

    Vanston, Alex

    2013-01-01

    This book uses a practical, step-by-step approach, starting with how to build directives from the ground up before moving on to creating web applications comprised of multiple modules all working together to provide the best user experience possible.This book is intended for intermediate JavaScript developers who are looking to enhance their understanding of single-page web application development with a focus on AngularJS and the JavaScript MVC frameworks.It is expected that readers will understand basic JavaScript patterns and idioms and can recognize JSON formatted data.

  13. jsGraph and jsNMR—Advanced Scientific Charting

    Directory of Open Access Journals (Sweden)

    Norman Pellet

    2014-09-01

    Full Text Available The jsGraph library is a versatile javascript library that allows advanced charting to be rendered interactively in web browsers without relying on server-side image processing. jsGraph is released under the MIT license and is free of charge. While being highly customizable through an intuitive javascript API, jsGraph is optimized to render a large quantity of data in a short amount of time. jsGraphs can display line, scatter, contour or zone series. Examples can be consulted on the project home page [1]. Customization of the chart, its axis and its series is achieved through simple but comprehensive JSON configurations.

  14. Instant IntroJs

    CERN Document Server

    Arasteh, Ehsan

    2013-01-01

    Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks. A simple starter that will guide you through IntroJs from scratch to advanced topics using a simple step by step approach with useful examples along the way.This book is for web designers who want to create an interactive step-by-step introduction for showing specific or all parts of an application or website to users. Basic JavaScript programming and knowledge of HTML and CSS is required. No knowledge of any other JavaScript libraries is needed

  15. AngularJS testing cookbook

    CERN Document Server

    Bailey, Simon

    2015-01-01

    This book is intended for developers who have an understanding of the basic principles behind both AngularJS and test-driven development. You, as a developer, are interested in eliminating the fear related to either introducing tests to an existing codebase or starting out testing on a fresh AngularJS application. If you're a team leader or part of a QA team with the responsibility of ensuring full test coverage of an application, then this book is ideal for you to comprehend the full testing scope required by your developers. Whether you're new to or are well versed with AngularJS, this book

  16. Instant AngularJS starter

    CERN Document Server

    Menard, Dan

    2013-01-01

    Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks. This book is written in an easytoread style, with a strong emphasis on realworld, practical examples. Stepbystep explanations are provided for performing important tasks.This book is for web developers familiar with JavascriptIt doesn't cover the history of AngularJS, and it's not a pitch to convince you that AngularJS is the best framework on the entire web. It's a guide to help you learn everything you need to know about AngularJS in as few pa

  17. KnockoutJS web development

    CERN Document Server

    Farrar, John

    2015-01-01

    This book is for web developers and designers who work with HTML and JavaScript to help them manage data and interactivity with data using KnockoutJS. Knowledge about jQuery will be useful but is not necessary.

  18. Node.js by example

    CERN Document Server

    Tsonev, Krasimir

    2015-01-01

    If you are a JavaScript developer with no experience with Node.js or server-side web development, this book is for you. It will lead you through creating a fairly complex social network. You will learn how to work with a database and create real-time communication channels.

  19. AngularJS test-driven development

    CERN Document Server

    Chaplin, Tim

    2015-01-01

    This book is for developers who want to learn about AngularJS development by applying testing techniques. You are assumed to have a basic knowledge and understanding of HTML, JavaScript, and AngularJS.

  20. Dependency injection with AngularJS

    CERN Document Server

    Knol, Alex

    2013-01-01

    This book is a practical, hands-on approach to using dependency injection and implementing test-driven development using AngularJS. Dependency Injection with AngularJS is aimed at developers who are aware of AngularJS but need to get started with using it in real life applications. Also, developers who want to get into test-driven development with AngularJS can use this book as practical guide. Even if you know about dependency injection, it can serve as a good reference on how it is used within AngularJS. Readers are expected to have some experience with JavaScript.

  1. AngularJS web application development

    CERN Document Server

    Darwin, Peter Bacon

    2013-01-01

    The book will be a step-by-step guide showing the readers how to build a complete web app with AngularJSJavaScript developers who want to learn AngularJS for developing web apps. Knowledge of JavaScript and HTML is expected. No knowledge of AngularJS is required.

  2. Responsive web design with AngularJS

    CERN Document Server

    Patel, Sandeep Kumar

    2014-01-01

    If you are an AngularJS developer who wants to learn about responsive web application development, this book is ideal for you. Responsive Web Design with AngularJS is intended for web developers or designers with a basic knowledge of HTML, CSS, and JavaScript.

  3. Practical Ext JS Projects with Gears

    CERN Document Server

    Zammetti, Frank

    2009-01-01

    Discover Ext JS, one of today's most powerful and highly regarded JavaScript frameworks, with perhaps the best set of GUI widgets around, and a whole host of components that make developing client--side applications a breeze. Using a pragmatic approach, you'll dissect seven full--fledged applications, covering *How Ext JS allows you to create these applications with a slick user interface with a minimum of effort*How the other parts of Ext JS aside from the GUI widgets provide many of the capabilities modern applications need, such as Ajax and data mechanisms *How other technologies such as Ge

  4. Data-oriented development with AngularJS

    CERN Document Server

    Waikar, Manoj

    2015-01-01

    This book helps beginner-level AngularJS developers organize AngularJS applications by discussing important AngularJS concepts and best practices. If you are an experienced AngularJS developer but haven't written directives or haven't created custom HTML controls before, then this book is ideal for you.

  5. Beginning Amazon Web Services with Node.js

    CERN Document Server

    Shackelford, Adam

    2015-01-01

    Beginning Amazon Web Services with Node.js teaches any novice Node.js developer to configure, deploy, and maintain scalable small to large scale Node.js applications in Amazon Web Services. Hosting a Node.js application in a production environment usually means turning to PaaS hosting, but this approach brings problems. Deploying Node.js directly to AWS solves the problems you encounter in these situations, enabling you to cut out the middle man. You will begin with a basic RESTful web service in Node.js, using the popular Express.js framework, pre-built and ready to run in your local env

  6. Cytoscape tools for the web age: D3.js and Cytoscape.js exporters

    Science.gov (United States)

    Ono, Keiichiro; Demchak, Barry; Ideker, Trey

    2014-01-01

    In this paper we present new data export modules for Cytoscape 3 that can generate network files for Cytoscape.js and D3.js. Cytoscape.js exporter is implemented as a core feature of Cytoscape 3, and D3.js exporter is available as a Cytoscape 3 app. These modules enable users to seamlessly export network and table data sets generated in Cytoscape to popular JavaScript library readable formats. In addition, we implemented template web applications for browser-based interactive network visualization that can be used as basis for complex data visualization applications for bioinformatics research. Example web applications created with these tools demonstrate how Cytoscape works in modern data visualization workflows built with traditional desktop tools and emerging web-based technologies. This interactivity enables researchers more flexibility than with static images, thereby greatly improving the quality of insights researchers can gain from them. PMID:25520778

  7. Cytoscape tools for the web age: D3.js and Cytoscape.js exporters.

    Science.gov (United States)

    Ono, Keiichiro; Demchak, Barry; Ideker, Trey

    2014-01-01

    In this paper we present new data export modules for Cytoscape 3 that can generate network files for Cytoscape.js and D3.js. Cytoscape.js exporter is implemented as a core feature of Cytoscape 3, and D3.js exporter is available as a Cytoscape 3 app. These modules enable users to seamlessly export network and table data sets generated in Cytoscape to popular JavaScript library readable formats. In addition, we implemented template web applications for browser-based interactive network visualization that can be used as basis for complex data visualization applications for bioinformatics research. Example web applications created with these tools demonstrate how Cytoscape works in modern data visualization workflows built with traditional desktop tools and emerging web-based technologies. This interactivity enables researchers more flexibility than with static images, thereby greatly improving the quality of insights researchers can gain from them.

  8. Data visualization with D3 and AngularJS

    CERN Document Server

    Körner, Christoph

    2015-01-01

    If you are a web developer with experience in AngularJS and want to implement interactive visualizations using D3.js, this book is for you. Knowledge of SVG or D3.js will give you an edge to get the most out of this book.

  9. Ember.js web development with Ember CLI

    CERN Document Server

    Puri, Suchit

    2015-01-01

    If you are a JavaScript developer who is starting out to build ambitious Ember.js application, or a developer who has prior Ember.js experience and want to transition your application to the latest Ember.js version with Ember CLI, then this book is for you.

  10. Instant Backbone.js application development

    CERN Document Server

    Hunter, Thomas

    2013-01-01

    Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks. This book is a practical, step-by-step tutorial that will teach you to build Backbone.js applications quickly and efficiently.This book is targeted towards developers. It is assumed that you have at least a basic understanding of JavaScript and jQuery selectors. If you are interested in building dynamic Single Page Applications that interact heavily with a backend server, then this is the book for you.

  11. Getting started with PhantomJS

    CERN Document Server

    Beltran, Aries

    2013-01-01

    The book will follow aA standard tutorial approach, and will beas a complete guide detailing the major aspects of PhantomJS with particular focus on Website website Testingtesting.This book is written forIf you are a JavaScript developers who are is interested in developing applications that interact with various web services, and doing that using a headless browser, then this book is ideal for you. This book iswill also be good for you if you are planning to create a headless browser testing for your web application. Basic understanding of JavaScript is assumed.

  12. Node.js ja reaaliaikainen viestintä

    OpenAIRE

    Skarp, Jani

    2015-01-01

    Insinöörityön tavoitteena oli luoda node.js-palvelinkehystä hyödyntävä reaaliaikainen keskusteluohjelma. Tavoitteena oli hyödyntää node.js:n nopeutta, mikä mahdollistaa reaaliaikaisten nettisovellusten luomisen. Tarkoituksena oli myös selvittää reaaliaikaisen viestinnän historiaa ja tarpeellisuutta ja miksi node.js soveltuu juuri reaaliaikaisten sovellusten tekemiseen. Luotu chat-ohjelma käyttää paljon hyödyksi node.js:n socket.io-moduulia. Socket.io antaa helpon tavan kommunikoida palvel...

  13. Sharepoint Extranet AngularJS:llä

    OpenAIRE

    2016-01-01

    Tämä opinnäytetyö käsittelee Sharepoint-ratkaisua AngularJS-ohjelmistokehyksen avulla. Työn tarkoituksena oli toteuttaa uusi sivusto Sharepoint-dokumenttikirjastoja varten. Tämä työ tehtiin toimeksiantona Visualweb Oy:lle. Tavoitteena oli tehdä Sharepoint-sivusto, joka toimisi varsinaisen Sharepoint-palvelimen etusivuna ja käyttöliittymänä. Sivusto toimii asiakkaalla käyttöliittymänä dokumenttikirjastoon. Käyn työssä läpi ne teknologiat, joita projektissa käytettiin. Työssä esitellään A...

  14. Building scalable apps with Redis and Node.js

    CERN Document Server

    Johanan, Joshua

    2014-01-01

    If the phrase scalability sounds alien to you, then this is an ideal book for you. You will not need much Node.js experience as each framework is demonstrated in a way that requires no previous knowledge of the framework. You will be building scalable Node.js applications in no time! Knowledge of JavaScript is required.

  15. Learning web development with Bootstrap and AngularJS

    CERN Document Server

    Radford, Stephen

    2015-01-01

    Whether you know a little about Bootstrap or AngularJS, or you're a complete beginner, this book will enhance your capabilities in both frameworks and you'll build a fully functional web app. A working knowledge of HTML, CSS, and JavaScript is required to fully get to grips with Bootstrap and AngularJS.

  16. The Words of Martin Luther King, Jr.

    Science.gov (United States)

    Today's Education, 1979

    1979-01-01

    Excerpts from speeches by Dr. Martin Luther King, Jr., are reprinted. Topics discussed include discrimination, the South, education, nonviolent resistance, poverty, economic opportunity, and world peace. (LH)

  17. HTML5 game programming with enchant.js

    CERN Document Server

    Shimizu, Ryo; Fushimi, Ryohei; Tanaka, Ryo; Kratzer, Kevin; McInnis, Brandon; Inc, enchantjs

    2013-01-01

    Official book from the developers of enchant.js. Enchant.js is open source, so there is no barrier for entry. Provides aspiring game developers with a tool to program fully-fledged games quickly and easily. Teaches the basics of HTML5 and JavaScript, invaluable tools for budding programmers. Shares invaluable tips from professional game developers for creating compelling game design and content.

  18. Edward Wheeler Hones Jr. (1922-2012)

    Science.gov (United States)

    Baker, Daniel N.; McPherron, Robert L.; Birn, Joachim

    2013-02-01

    Space physicist Edward Wheeler Hones Jr. died on 17 September 2012 at his home in Los Alamos, N. M. He was 90 years old. The cause of death was a heart attack that came following a brief hospitalization.

  19. Tvorba webové aplikace v Node.js

    OpenAIRE

    Homolka, David

    2016-01-01

    Thesis deals with development of Web Application in Node.js. Web solution represents visualization of many various meteorological data and fills it into maps of planet Earth. User can view any available data about world weather or he can upload own file with data. The complete application is created in JavaScript, which is used on client side and server side.

  20. Instant dependency management with RequireJS how-to

    CERN Document Server

    Franko, Greg

    2013-01-01

    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks.A concise guide that delivers immediate results with practical recipes on customizing your projects.This book is for intermediate to advanced JavaScript developers who are interested in learning more about AMD specification and RequireJS.

  1. jsCoq: Towards Hybrid Theorem Proving Interfaces

    Directory of Open Access Journals (Sweden)

    Emilio Jesús Gallego Arias

    2017-01-01

    Full Text Available We describe jsCcoq, a new platform and user environment for the Coq interactive proof assistant. The jsCoq system targets the HTML5–ECMAScript 2015 specification, and it is typically run inside a standards-compliant browser, without the need of external servers or services. Targeting educational use, jsCoq allows the user to start interaction with proof scripts right away, thanks to its self-contained nature. Indeed, a full Coq environment is packed along the proof scripts, easing distribution and installation. Starting to use jsCoq is as easy as clicking on a link. The current release ships more than 10 popular Coq libraries, and supports popular books such as Software Foundations or Certified Programming with Dependent Types. The new target platform has opened up new interaction and display possibilities. It has also fostered the development of some new Coq-related technology. In particular, we have implemented a new serialization-based protocol for interaction with the proof assistant, as well as a new package format for library distribution.

  2. Web development with MongoDB and Node.js

    CERN Document Server

    Krol, Jason

    2014-01-01

    This book is designed for developers of any skill level that want to get up and running using Node.js and MongoDB to build full featured web applications. A basic understanding of JavaScript and HTML is the only requirement for this book.

  3. Living history: G. Edgar Folk, Jr.

    Science.gov (United States)

    Tipton, Charles M

    2008-06-01

    In 2005, the American Physiological Society (APS) initiated the Living History Project to recognize senior members who have made significant contributions during their career to the advancement of the discipline and profession of physiology. During 2007, the APS Section of Environmental and Exercise Physiology selected Prof. G. Edgar Folk, Jr., of the University of Iowa to be profiled in Advances in Physiology Education.

  4. Martin Luther King, Jr. Resource Guide.

    Science.gov (United States)

    New York State Education Dept., Albany. Div. of Civil Rights and Intercultural Relations.

    This resource guide was developed to commemorate Dr. Martin Luther King, Jr.'s birthday by providing school personnel with background information and hands-on activities for use with students in Grades K-12. The activities in the guide can be implemented throughout the school year to help students become aware of the social, economic, and…

  5. Martin Luther King, Jr. Teacher's Resource Manual.

    Science.gov (United States)

    Connecticut State Dept. of Education, Hartford.

    This Connecticut teachers' manual on Martin Luther King, Jr. includes: (1) teacher background information; (2) five excerpts from King's speeches; (3) four themes for lesson plans; and (4) sample lesson plans. The teacher's background information provides biographical sketches of King and his precursors. The five speeches reproduced here are…

  6. Views of Dr. Martin Luther King, Jr.

    Science.gov (United States)

    Davis, Alan H.

    1990-01-01

    Discusses views of Martin Luther King, Jr., including concepts of human rights, related counseling approaches, and ethics. Claims King's views provide helpful insights for counselors and clients. Concludes King invited individuals to view challenging life situations as moral opportunities. (Author/ABL)

  7. Books about Martin Luther King, Jr.

    Science.gov (United States)

    Woll, Christina B.

    1990-01-01

    Briefly reviews three recent biographies of Martin Luther King, Jr. that also deal with the civil rights movement. Summarizes contents and identifies reading ability levels appropriate for elementary and junior high students. Recommends six additional King biographies for children. Also endorses two filmstrips on King and the movement. Gives full…

  8. 20 CFR 658.420 - Establishment of JS complaint system at the ETA regional office.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Establishment of JS complaint system at the ETA regional office. 658.420 Section 658.420 Employees' Benefits EMPLOYMENT AND TRAINING... Complaint System Federal Js Complaint System § 658.420 Establishment of JS complaint system at the...

  9. RESTful web API design with Node.js

    CERN Document Server

    Bojinov, Valentin

    2015-01-01

    If you are a web developer wanting to enrich your development skills to create scalable, server-side, RESTful applications based on the Node.js platform, this book is for you. You also need to be aware of HTTP communication concepts and should have a working knowledge of JavaScript. Knowledge of REST would be an added advantage but is definitely not a necessity.

  10. Learning Three.js the JavaScript 3D library for WebGL

    CERN Document Server

    Dirksen, Jos

    2013-01-01

    ""Learning Three.js is a hands-on guide which provides everything you need to start working with the powerful JavaScript library, and start creating awesome in-browser visualizations"".Learning Three.js is written for anyone looking to get started with Three.js, or looking to improve their skills with the popular js library. The book assumes some knowledge of javascript, but you don't need any knowledge of Three.js itself to follow the book.

  11. Vcs.js - Visualization Control System for the Web

    Science.gov (United States)

    Chaudhary, A.; Lipsa, D.; Doutriaux, C.; Beezley, J. D.; Williams, D. N.; Fries, S.; Harris, M. B.

    2016-12-01

    VCS is a general purpose visualization library, optimized for climate data, which is part of the UV-CDAT system. It provides a Python API for drawing 2D plots such as lineplots, scatter plots, Taylor diagrams, data colored by scalar values, vector glyphs, isocontours and map projections. VCS is based on the VTK library. Vcs.js is the corresponding JavaScript API, designed to be as close as possible to the original VCS Python API and to provide similar functionality for the Web. Vcs.js includes additional functionality when compared with VCS. This additional API is used to introspect data files available on the server and variables available in a data file. Vcs.js can display plots in the browser window. It always works with a server that reads a data file, extracts variables from the file and subsets the data. From this point, two alternate paths are possible. First the system can render the data on the server using VCS producing an image which is send to the browser to be displayed. This path works for for all plot types and produces a reference image identical with the images produced by VCS. This path uses the VTK-Web library. As an optimization, usable in certain conditions, a second path is possible. Data is packed, and sent to the browser which uses a JavaScript plotting library, such as plotly, to display the data. Plots that work well in the browser are line-plots, scatter-plots for any data and many other plot types for small data and supported grid types. As web technology matures, more plots could be supported for rendering in the browser. Rendering can be done either on the client or on the server and we expect that the best place to render will change depending on the available web technology, data transfer costs, server management costs and value provided to users. We intend to provide a flexible solution that allows for both client and server side rendering and a meaningful way to choose between the two. We provide a web-based user interface called v

  12. Instant Ember.js application development how-to

    CERN Document Server

    Bodmer, Marc

    2013-01-01

    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks. Get the job done and learn as you go. A how-To book with practical recipes accompanied with rich screenshots for easy comprehension.This book follows a recipe-based approach that can be used both for problem solving or getting started with Ember.JS. Regardless of your skill level you should find this book useful and beneficial to any of your application development projects.Are you a frontend developer whose code has gotten out of control? This book will also show you how you can us

  13. Anatomy of BioJS, an open source community for the life sciences.

    Science.gov (United States)

    Yachdav, Guy; Goldberg, Tatyana; Wilzbach, Sebastian; Dao, David; Shih, Iris; Choudhary, Saket; Crouch, Steve; Franz, Max; García, Alexander; García, Leyla J; Grüning, Björn A; Inupakutika, Devasena; Sillitoe, Ian; Thanki, Anil S; Vieira, Bruno; Villaveces, José M; Schneider, Maria V; Lewis, Suzanna; Pettifer, Steve; Rost, Burkhard; Corpas, Manuel

    2015-07-08

    BioJS is an open source software project that develops visualization tools for different types of biological data. Here we report on the factors that influenced the growth of the BioJS user and developer community, and outline our strategy for building on this growth. The lessons we have learned on BioJS may also be relevant to other open source software projects.

  14. Tribute to A. W. Castleman, Jr.

    Energy Technology Data Exchange (ETDEWEB)

    Knappenberger, Jr., Kenneth L.; Johnson, Grant E.; El-Sayed, Mostafa A.

    2014-09-18

    It is with great pleasure that we join our many colleagues who contributed to this special issue of The Journal of Physical Chemistry A in dedicating it in honor of Professor A. W. “Will” Castleman, Jr. Will is a pioneer in the field of cluster science, and the far-reaching impact of his career is demonstrated by the broad range of topics covered in this issue. This diversity validates Will’s teaching that “fundamental research in cluster science allows you to explore any problem you want”. This ability to extend to other research areas comes because, as Will has shown both rigorously and elegantly, clusters are an intermediate state of matter that bridge the gap between molecular and bulk levels.

  15. Ultra light weight jet engine JR100; Chokeiryo jet engine JR100

    Energy Technology Data Exchange (ETDEWEB)

    Matsuki, M. [Nippon Institute of Technology, Saitama (Japan)

    1999-03-20

    As a part of the jet lift V/STOL research by National Aerospace Laboratory, a study of trial manufacture of ultra light weight jet engine JR 100 started in FY 1964. The study was aimed at obtaining a lift engine for VTOL and founding the base for the future jet lift VTOL, and at taking in the results of the jet engine element study accumulated so far and manufacturing an advanced engine. Decided on the use of domestic materials for JR 100, the materials to be used are almost iron-based ones. Through the efforts for weight reduction in structure and processing, a thrust/weight ratio of 10 was realized. At the same time, the production/processing of light weight materials such as titanium alloys was proceeded with, and by adopting the materials to JR 200 system, a thrust/weight ratio of 15 was realized. Together with these, for the purpose of reducing the fuel consumption rate, studies started on fan for lift fan engine and high temperature turbine (an inlet temperature of 1250 degrees C was achieved), to get low noise/high efficiency fan. By the research results, the basis for jet lift VTOL was established, and it became the basis for the development of turbo fan engine FJR 710. (NEDO)

  16. The Newest Monument: The Martin Luther King, Jr. National Memorial

    Science.gov (United States)

    Social Studies and the Young Learner, 2011

    2011-01-01

    This article features the newest monument, the Martin Luther King, Jr. National Memorial. The memorial on the National Mall in Washington, D.C., honoring Dr. Martin Luther King, Jr. will be an engaging landscape experience to convey four fundamental and recurring themes throughout Dr. King's life--democracy, justice, hope, and love. Natural…

  17. Purification and characterization of water soluble polysaccharide JS1 from Hippophae rhamnoides%沙棘果水溶多糖JS1的分离鉴定

    Institute of Scientific and Technical Information of China (English)

    王桂云; 梁忠岩; 张丽萍; 苗春艳

    1999-01-01

    OBJECTIVE:To study the purification and characterization of water soluble polysaccharide JS1 from Hippophae rahamnoides L.fruits that had been extracted with water.METHODS:JS1 was purified by gel chromatography on DEAE-Sep-hadex A-25.its homogeneity was proved by gel chromatogrophy on Sepharose CL-4B glass fiber paper electrophoresis and specific rotator power.Its stral composition was studied by means of GC,IR,etc.RESULTS:JS1 is a water solube polysaccharide.It is consisted of Ara,Xyl,Gal,Glc with the molarity rate of 1∶6∶12∶4 in turn by means of GC.CONCLUSION:JS1 is a neutral heteropolysaccharide.%目的:从已提取过水溶性多糖后的沙棘果残渣中,进一步用稀碱液(0.1mol.L-1NaOH溶液)提取多糖JS1,并研究其组成性质。方法:利用DEAE-Sephadex A-25柱层析法纯化沙棘果碱提水溶多糖,并采用玻璃纤维纸电泳,Sepharos CL-4B柱层析比旋度等方法证明组分的均一性,同时用气相色谱、红外光谱等方法对其组成进行研究。结果:分离得到JS1水溶性多糖,经气相色谱分析得单糖组分为Ara,Xyl,Gal,Glc,摩尔比依次是1∶6∶12∶4。结论:JS1为中性杂多糖。

  18. Laenumiljonid tuulte meelevallas / Toomas Mattson

    Index Scriptorium Estoniae

    Mattson, Toomas, 1970-

    2005-01-01

    Ilmunud ka: Põhjarannik 4. märts lk. 2, Severnoje Poberezhje 4. märts, lk. 2. Ülevaade Riigikontrolli auditist Maaelu Edendamise Sihtasutuse tegevuse kohta. Kommenteerivad Ester Tuiksoo ja Raul Rosenberg

  19. Draft genome sequence of Therminicola potens strain JR

    Energy Technology Data Exchange (ETDEWEB)

    Byrne-Bailey, K.G.; Wrighton, K.C.; Melnyk, R.A.; Agbo, P.; Hazen, T.C.; Coates, J.D.

    2010-07-01

    'Thermincola potens' strain JR is one of the first Gram-positive dissimilatory metal-reducing bacteria (DMRB) for which there is a complete genome sequence. Consistent with the physiology of this organism, preliminary annotation revealed an abundance of multiheme c-type cytochromes that are putatively associated with the periplasm and cell surface in a Gram-positive bacterium. Here we report the complete genome sequence of strain JR.

  20. Walter Rowe Courtenay, Jr. (1933–2014)

    Science.gov (United States)

    Benson, Amy J.

    2016-01-01

    WALTER R. COURTENAY, JR., ichthyologist and retired professor, Florida Atlantic University, Boca Raton, Florida, died in Gainesville, Florida, on 30 January 2014 at age 80. Walt was born in Neenah, Wisconsin, on 6 November 1933, son of Walter and Emily Courtenay. Walt's interest in fish began at a young age as evidenced by a childhood diary in which at 13 years of age he wrote about his first catch—a two-and-a-half pound “pike” from Lake Winnebago. When Walt turned ten, the family moved from Wisconsin to Nashville, Tennessee, the move precipitated by his father accepting a position as pastor of the First Presbyterian Church. During those early days in Nashville, Walt's father would take summers off and travel to Michigan to teach at Camp Miniwanca along the shore of Lake Michigan where father and son honed their angling skills. It was also at that time Walt's father had definite views on what his son should be doing in adult life—in Walt's case it was to become a medical doctor. However, his Woods Hole internship in marine biology and oceanography toward the end of his undergraduate years was a transformative experience for him so much so that he abandoned all ideas of becoming a medical doctor and instead specialized in ichthyology and oceanography. Apart from the inherent interest and opportunities Woods Hole opened to him, being back at the shore of a large body of water, in this case the Atlantic Ocean, was far more interesting than sitting in lectures on organic chemistry. With that, Walt completed his B.A. degree at Vanderbilt University in 1956. In 1960 while in graduate school in Miami, Walt met and married Francine Saporito, and over the next several years had two children, Walter III and Catherine. He went on to receive his M.S. in 1961 from The Rosenstiel School of Marine and Atmospheric Science at the University of Miami on the systematics of the genus Haemulon (grunts) and his Ph.D. degree in 1965 working under his advisor C. Richard

  1. jsPsych: a JavaScript library for creating behavioral experiments in a Web browser.

    Science.gov (United States)

    de Leeuw, Joshua R

    2015-03-01

    Online experiments are growing in popularity, and the increasing sophistication of Web technology has made it possible to run complex behavioral experiments online using only a Web browser. Unlike with offline laboratory experiments, however, few tools exist to aid in the development of browser-based experiments. This makes the process of creating an experiment slow and challenging, particularly for researchers who lack a Web development background. This article introduces jsPsych, a JavaScript library for the development of Web-based experiments. jsPsych formalizes a way of describing experiments that is much simpler than writing the entire experiment from scratch. jsPsych then executes these descriptions automatically, handling the flow from one task to another. The jsPsych library is open-source and designed to be expanded by the research community. The project is available online at www.jspsych.org .

  2. Scalable Web Application using Node.JS and CouchDB

    OpenAIRE

    Paudyal, Umesh

    2011-01-01

    This report presents design and implementation of a protoype application using server side javascript programming language, node.JS and couchDB as backend database. It scales and evaluates the developed prototype application and the couchDB for their scalability and performance. The report concludes that node.JS is a suitable framework for development of scalable web servers and couchDB as a backend database, though natively not distributed and scalable, can be scaled and distributed across m...

  3. Dose distribution, using homogeneous material before the reload of the JS-6500 irradiator; Distribucion de dosis, empleando material homogeneo antes de la recarga del irradiador JS-6500

    Energy Technology Data Exchange (ETDEWEB)

    Carrasco A, H

    1991-10-15

    The objective of this report is to determine the dose distribution inside the aluminum containers used for the industrial irradiation, as well as to locate the positions of maximum and minimum doses, before the reloading of the JS-6500 Irradiator. (Author)

  4. Obituary: Leverett Davis, Jr., 1914-2003

    Science.gov (United States)

    Jokipii, Jack Randolph

    2004-12-01

    Professor Leverett Davis Jr., Professor of theoretical physics at the California Institute of Technology, died on June 15, 2003 after a long illness. He was 89 years old. He contributed many important ideas and concepts to theoretical astrophysics and was a pioneer in the in situ scientific exploration of space using observations from spacecraft. Davis was born in Elgin, Illinois on March 3, 1914, the eldest of four children of Louis Leverett Davis and Susan Gulick Davis. His parents moved several times as he grew up because his father, a mining engineer, became involved in different mining operations in the American West. Leverett married Victoria Stocker in June 1943. They had two children who died in childhood and subsequently adopted a son, Jeffrey. His wife and son survive him. Davis's early education was rather fractured and uneven because of the many family moves, with periods of home schooling alternating with regular school. His high school education was, on the other hand, reasonably normal. It was while in high school that he decided that he wanted to do physics or mathematics. He went on to earn his Bachelor of Science degree at Oregon State College in 1936, after which he started graduate studies at the California Institute of Technology, to pursue a graduate degree in physics. His advisor was William V. Houston and Davis received his PhD in 1941 for a thesis on electrical properties in nerves. He briefly entertained the idea of changing to work in biophysics. During World War II, Davis became an integral member of the Caltech project for rockets, which developed a number of different types of rockets used in the war. As a result of this war work, Davis wrote a book on Exterior Ballistics, published by Van Nostrand in 1958. He joined the faculty at the California Institute of Technology in 1946, after several years on campus as an instructor. In all, he taught there for nearly four decades before retiring as Professor of Theoretical Physics in 1981

  5. JS-K, a nitric oxide-releasing prodrug, induces breast cancer cell death while sparing normal mammary epithelial cells.

    Science.gov (United States)

    McMurtry, Vanity; Saavedra, Joseph E; Nieves-Alicea, René; Simeone, Ann-Marie; Keefer, Larry K; Tari, Ana M

    2011-04-01

    Targeted therapy with reduced side effects is a major goal in cancer research. We investigated the effects of JS-K, a nitric oxide (NO) prodrug designed to release high levels of NO when suitably activated, on human breast cancer cell lines, on non-transformed human MCF-10A mammary cells, and on normal human mammary epithelial cells (HMECs). Cell viability assay, flow cytometry, electron microscopy, and Western blot analysis were used to study the effects of JS-K on breast cancer and on mammary epithelial cells. After a 3-day incubation, the IC50s of JS-K against the breast cancer cells ranged from 0.8 to 3 µM. However, JS-K decreased the viability of the MCF-10A cells by only 20% at 10-µM concentration, and HMECs were unaffected by 10 µM JS-K. Flow cytometry indicated that JS-K increased the percentages of breast cancer cells under-going apoptosis. Interestingly, flow cytometry indicated that JS-K increased acidic vesicle organelle formation in breast cancer cells, suggesting that JS-K induced autophagy in breast cancer cells. Electron microscopy confirmed that JS-K-treated breast cancer cells underwent autophagic cell death. Western blot analysis showed that JS-K induced the expression of microtubule light chain 3-II, another autophagy marker, in breast cancer cells. However, JS-K did not induce apoptosis or autophagy in normal human mammary epithelial cells. These data indicate that JS-K selectively induces programmed cell death in breast cancer cells while sparing normal mammary epithelial cells under the same conditions. The selective anti-tumor activity of JS-K warrants its further investigation in breast tumors.

  6. Future Jet Technologies. Part B. F-35 Future Risks v. JS-Education of Pilots & Engineers

    Science.gov (United States)

    Gal-Or, Benjamin

    2011-09-01

    Design of “Next-Generation” airframes based on supermarket-jet-engine-components is nowadays passé. A novel integration methodology [Gal-Or, “Editorial-Review, Part A”, 2011, Gal-Or, “Vectored Propulsion, Supermaneuverability and Robot Aircraft”, Springer Verlag, Gal-Or, Int'l. J. of Thermal and Fluid Sciences 7: 1-6, 1998, “Introduction”, 2011] is nowadays in. For advanced fighter aircraft it begins with JS-based powerplant, which takes up to three times longer to mature vis-à-vis the airframe, unless “committee's design” enforces a dormant catastrophe. Jet Steering (JS) or Thrust Vectoring Flight Control, is a classified, integrated engine-airframe technology aimed at maximizing post-stall-maneuverability, flight safety, efficiency and flight envelopes of manned and unmanned air vehicles, especially in the “impossible-to-fly”, post-stall flight domains where the 100+ years old, stall-spin-limited, Conventional Flight Control fails. Worldwide success in adopting the post-stall, JS-revolution, opens a new era in aviation, with unprecedented design variables identified here for a critical review of F-35 future risks v. future fleets of jet-steered, pilotless vehicles, like the X-47B/C. From the educational point of view, it is also instructive to comprehend the causes of long, intensive opposition to adopt post-stall, JS ideas. A review of such debates may also curb a future opposition to adopt more advanced, JS-based technologies, tests, strategies, tactics and missions within the evolving air, marine and land applications of JS. Most important, re-education of pilots and engineers requires adding post-stall, JS-based studies to curriculum & R&D.

  7. Puesta en marcha del sensor fuerza-par JR3

    OpenAIRE

    Hoz Najarro, Carlos de la

    2011-01-01

    Este estudio se engloba dentro de los proyectos realizados por el grupo de trabajo Robotic Lab de la Universidad Carlos III de Madrid para el desarrollo del nuevo Humanoide RH-2. Concretamente, implementaremos sobre software libre (Linux) una aplicación C++ que nos permita obtener de la tarjeta de adquisición de datos de 4 puertos PCI P/N 1593 de JR3 inc., en tiempo real, los valores de fuerza/par del sensor industrial Force Moment Sensor 85M35A3-I40-DH12, de la compañía JR3 inc., que llevará...

  8. Writing, Teaching, and Researching: An Interview with Rene Saldana, Jr.

    Science.gov (United States)

    Saldana, Rene, Jr.; Moore, David W.

    2010-01-01

    Rene Saldana, Jr., an assistant professor at Texas Tech University, is a writer of short stories, poetry, and novels. In order to get his storytelling right, he has relied on his memory when writing memoirs and consulted popular culture and family when writing fiction. In order to get his university teaching right, he reads seminal texts on…

  9. Martin Luther King, Jr.: The Dream of Peaceful Revolution.

    Science.gov (United States)

    Rowland, Della

    This biography for younger readers depicts the life of Martin Luther King, Jr., the Nobel Peace Prize winner who dedicated himself to the struggle for equal rights for African Americans while embracing the principle of nonviolent resistance. The book presents an overview of the civil rights movement and chronicles King's role as national leader…

  10. Celebrate the legacy of Dr. Martin Luther King Jr.

    OpenAIRE

    Lazenby, Jenna

    2006-01-01

    In celebration of the life and legacy of Dr. Martin Luther King, Jr., Virginia Tech will host a variety of educational and cultural programs and community service events Jan. 14-19, 2007. All events are free and open to the public.

  11. A Conservation with...Henry Louis Gates, Jr.

    Science.gov (United States)

    Cheney, Lynne V.

    1991-01-01

    Presents an interview between National Endowment for the Humanities chairman, Lynne V. Cheney, and Harvard professor, Henry Louis Gates, Jr. Includes discussion of multiculturalism as it relates to free speech, sexism, racism, hate speech, and ethnocentrism. Emphasizes both the open tradition of Western culture and the recent pressure for…

  12. Celebrate the legacy of Dr. Martin Luther King Jr.

    OpenAIRE

    Lazenby, Jenna

    2006-01-01

    In celebration of the life and legacy of Dr. Martin Luther King, Jr., Virginia Tech will host a variety of educational and cultural programs and community service events Jan. 14-19, 2007. All events are free and open to the public.

  13. Henry David Thoreau and Martin Luther King, Jr. Lesson Plan.

    Science.gov (United States)

    Powell, Brent

    1995-01-01

    Presents a five-lesson, high school instructional unit on the ideas and activities of Henry David Thoreau and Martin Luther King, Jr. Includes student objectives, step-by-step instructional procedures, and discussion questions. Provides quotations by Thoreau and King. (CFR)

  14. Dr. Martin Luther King, Jr. Washington State Resource Guide.

    Science.gov (United States)

    Washington Office of the State Superintendent of Public Instruction, Olympia, WA. Div. of Instructional Programs and Services.

    The Washington State Resource Guide on Martin Luther King, Jr., supplies a wide variety of materials for use with all grade levels in classroom and assembly presentations in public schools. The goal is for every child enrolled in Washington State schools to learn about Dr. King during the days of January 15 to January 17. Resolutions supporting an…

  15. Martin Luther King Jr.: The Crozer Seminary Years.

    Science.gov (United States)

    Carson, Clayborne

    1997-01-01

    As an undergraduate at Morehouse College, Martin Luther King Jr. was not a strong student, although he excelled in oratory, but in his years at Crozer Theological Seminary in Pennsylvania he applied himself to become a straight-A student. The development of his theological perspective is described. (SLD)

  16. A Dr. Martin Luther King, Jr. Curriculum: Playing the Dream.

    Science.gov (United States)

    Clemens, Sydney Gurewitz

    1988-01-01

    Discusses curriculum for young children centered around the beliefs and teachings of Dr. Martin Luther King, Jr. His works are interpreted in a human rights context in which children find their voice in the peaceable resolution of everyday conflicts. Describes the Child of the Day program. (Author/RWB)

  17. Finding the Right Formula: Edwin H. Walker Jr

    Science.gov (United States)

    Keels, Crystal L.

    2005-01-01

    Edwin H. Walker Jr earned his doctorate in chemistry at age 27 and has barely looked back. With 13 publications under his belt before coming out of graduate school, he has also given more than 20 poster presentations in national venues, most recently at the American Chemical Society. He can also include securing a half-million-dollar National…

  18. Využití MongoDB s Node.js

    OpenAIRE

    Hejtmánková, Kateřina

    2015-01-01

    The aim of my thesis is to provide a collection of examples about document oriented MongoDB database using Node.js platform, specifically using the Mongoose program, for object-document mapping (ODM). The aim is met by analysis of Mongoose and Async module, which provides functions for more comprehensive asynchronous querying, needed for working with input/output to the MongoDB database in Node.js. The main merit of this thesis is (in the general sense) a demonstration of how to create a admi...

  19. Genome Sequence of the Ethene- and Vinyl Chloride-Oxidizing Actinomycete Nocardioides sp Strain JS614

    Energy Technology Data Exchange (ETDEWEB)

    Coleman, Nicholas V [University of Sydney, Australia; Wilson, Neil L [University of Sydney, Australia; Barry, Kerrie [U.S. Department of Energy, Joint Genome Institute; Bruce, David [Los Alamos National Laboratory (LANL); Copeland, A [U.S. Department of Energy, Joint Genome Institute; Dalin, Eileen [U.S. Department of Energy, Joint Genome Institute; Detter, J. Chris [U.S. Department of Energy, Joint Genome Institute; Glavina Del Rio, Tijana [U.S. Department of Energy, Joint Genome Institute; Goodwin, Lynne A. [Los Alamos National Laboratory (LANL); Hammon, Nancy [U.S. Department of Energy, Joint Genome Institute; Han, Shunsheng [Los Alamos National Laboratory (LANL); Hauser, Loren John [ORNL; Israni, Sanjay [U.S. Department of Energy, Joint Genome Institute; Kim, Edwin [U.S. Department of Energy, Joint Genome Institute; Kyrpides, Nikos C [U.S. Department of Energy, Joint Genome Institute; Land, Miriam L [ORNL; Lapidus, Alla L. [U.S. Department of Energy, Joint Genome Institute; Larimer, Frank W [ORNL; Lucas, Susan [U.S. Department of Energy, Joint Genome Institute; Pitluck, Sam [U.S. Department of Energy, Joint Genome Institute; Richardson, Paul [U.S. Department of Energy, Joint Genome Institute; Schmutz, Jeremy [Stanford University; Tapia, Roxanne [Los Alamos National Laboratory (LANL); Thompson, Sue [Los Alamos National Laboratory (LANL); Tice, Hope [U.S. Department of Energy, Joint Genome Institute; Spain, Jim C [Georgia Institute of Technology; Gossett, James G [Cornell University; Mattes, Timothy E [University of Iowa

    2011-01-01

    Nocardioides sp. strain JS614 grows on ethene and vinyl chloride (VC) as sole carbon and energy sources and is of interest for bioremediation and biocatalysis. Sequencing of the complete genome of JS614 provides insight into the genetic basis of alkene oxidation, supports ongoing research into the physiology and biochemistry of growth on ethene and VC, and provides biomarkers to facilitate detection of VC/ethene oxidizers in the environment. This is the first genome sequence from the genus Nocardioides and the first genome of a VC/ethene-oxidizing bacterium.

  20. High performance geospatial and climate data visualization using GeoJS

    Science.gov (United States)

    Chaudhary, A.; Beezley, J. D.

    2015-12-01

    GeoJS (https://github.com/OpenGeoscience/geojs) is an open-source library developed to support interactive scientific and geospatial visualization of climate and earth science datasets in a web environment. GeoJS has a convenient application programming interface (API) that enables users to harness the fast performance of WebGL and Canvas 2D APIs with sophisticated Scalable Vector Graphics (SVG) features in a consistent and convenient manner. We started the project in response to the need for an open-source JavaScript library that can combine traditional geographic information systems (GIS) and scientific visualization on the web. Many libraries, some of which are open source, support mapping or other GIS capabilities, but lack the features required to visualize scientific and other geospatial datasets. For instance, such libraries are not be capable of rendering climate plots from NetCDF files, and some libraries are limited in regards to geoinformatics (infovis in a geospatial environment). While libraries such as d3.js are extremely powerful for these kinds of plots, in order to integrate them into other GIS libraries, the construction of geoinformatics visualizations must be completed manually and separately, or the code must somehow be mixed in an unintuitive way.We developed GeoJS with the following motivations:• To create an open-source geovisualization and GIS library that combines scientific visualization with GIS and informatics• To develop an extensible library that can combine data from multiple sources and render them using multiple backends• To build a library that works well with existing scientific visualizations tools such as VTKWe have successfully deployed GeoJS-based applications for multiple domains across various projects. The ClimatePipes project funded by the Department of Energy, for example, used GeoJS to visualize NetCDF datasets from climate data archives. Other projects built visualizations using GeoJS for interactively exploring

  1. Node.js:a new technology to build Web application%Node.js:一种新的Web应用构建技术

    Institute of Scientific and Technical Information of China (English)

    王金龙; 宋斌; 丁锐

    2015-01-01

    现如今,有很多种Web应用程序开发语言。在Web应用程序开发过程中,大部分语言都要解决多线程问题。而且这些Web应用程序都要部署在第三方Web服务器上,如:Apache,Tomcat,Nginx等。近期一种基于I/O事件驱动模型服务器端的JavaScript运行环境——Node.js得到了广泛的关注和应用。通过对同步阻塞语言PHP和异步非阻塞的Node.js构建的Web应用程序做一些性能上的比较,发现在高并发请求的情况下,Node.js构建的服务器比PHP构建的应用程序的响应时间短、吞吐率高。最终得出结论Node.js在构建快速、可扩展的Web应用程序方面的优势大于PHP。%Nowadays,there are many program languages to build Web application. During developing Web application,the most of languages must handle multithreading problem. In addition,these Web application programs must be deployed in a third⁃party Web server,such as Apache,Tomcat,Nginx and so on. Recently,Node.js,an event⁃driven server⁃side JavaScript envi⁃ronment based on I/O has been widely concerned and applied. In this paper,via comparing the performance of the Web applica⁃tion built by synchronous blocking PHP and asynchronous non⁃blocking Node.js,it is found that the response time of the Web server built by Node.js is shorter than PHP and the throughput of Node.js is higher than PHP in the case of high concurrent re⁃quests. A conclusion that Node.js is superior to PHP in building fast and scalable Web application program is obtained eventually.

  2. Martin Luther King Jr. contest winning posters to be displayed in downtown Blacksburg

    OpenAIRE

    Shannon, Kelly Baker

    2010-01-01

    Each year as part of the Martin Luther King Jr. celebration at Virginia Tech area kindergarten through 12th grade students are invited to participate in the annual Martin Luther King Jr. poster contest.

  3. PhoneGap and AngularJS for cross-platform development

    CERN Document Server

    Liang, Yuxian Eugene

    2014-01-01

    This book is intended for people who are not familiar with AngularJS and who want to take their PhoneGap development skills further by developing apps using different JavaScript libraries. People with some knowledge of PhoneGap, HTML, CSS, and JavaScript will find this book immediately useful.

  4. 20 CFR 658.421 - Handling of JS-related complaints.

    Science.gov (United States)

    2010-04-01

    ... ETA regional office level until the complainant has exhausted the State agency administrative remedies... Administrator. However, nothing in this provision shall prevent an ETA regional office from accepting and handling to resolution a JS-related complaint pursuant to § 658.423 or § 658.702(c). (b) The ETA...

  5. From flipchart to glossy visualisation through collaboration and d3.js

    CERN Document Server

    CERN. Geneva

    2015-01-01

    Representing complex data visually is an important tool for communication, and the CERN Knowledge Transfer Annual Report is no exception to this. I want to share with the audience our experience with data visualization through the strength of collaboration, and the power and simplicity of the d3.js javascript framework.

  6. Dr. John H. Hopps Jr. Research Scholars Program

    Science.gov (United States)

    2014-10-20

    graduates’ majors, honors/awards and their acceptance to a doctoral program. Also, assisting with securing the keynote speaker, Dr. Jimmie Lee Davis, Jr...experiences during school semesters and in the summers, and scholastic information such as college majors, minors, graduations, degree pursuits, fellowships...climate change. The Morehouse Hopps Alumni Panel included seven graduates who are currently in various levels of graduate school. Their candid

  7. Jaagsiekte sheep retrovirus proviral clone JSRV(JS7), derived from the JS7 lung tumor cell line, induces ovine pulmonary carcinoma and is integrated into the surfactant protein A gene.

    Science.gov (United States)

    DeMartini, J C; Bishop, J V; Allen, T E; Jassim, F A; Sharp, J M; de las Heras, M; Voelker, D R; Carlson, J O

    2001-05-01

    Ovine pulmonary carcinoma (OPC) is a contagious neoplasm of alveolar epithelial type II (ATII) or Clara cells caused by a type D/B chimeric retrovirus, jaagsiekte sheep retrovirus (JSRV). Here we report the isolation, sequencing, pathogenicity, and integration site of a JSRV provirus isolated from a sheep lung tumor cell line (JS7). The sequence of the virus was 93 to 99% identical to other JSRV isolates and contained all of the expected open reading frames. To produce virions and test its infectivity, the JS7 provirus (JSRV(JS7)) was cloned into a plasmid containing a cytomegalovirus promoter and transfected into 293T cells. After intratracheal inoculation with virions from concentrated supernatant fluid, JSRV-associated OPC lesions were found in one of four lambs, confirming that JSRV(JS7) is pathogenic. In JS7-cell DNA, the viral genome was inserted in the protein-coding region for the surfactant protein A (SP-A) gene, which is highly expressed in ATII cells, in an orientation opposite to the direction of transcription of the SP-A gene. No significant transcription was detected from either the viral or the SP-A gene promoter in the JS7 cell line at passage level 170. The oncogenic significance of the JSRV proviral insertion involving the SP-A locus in the JS7 tumor cell line is unknown.

  8. DCEG Symposium to Honor Joseph F. Fraumeni, Jr. | Poster

    Science.gov (United States)

    By Nancy Parrish, Staff Writer On May 6, the Division of Cancer Epidemiology and Genetics (DCEG) will sponsor a symposium to honor 50 years of leadership from its founding director, Joseph F. Fraumeni, Jr., M.D., who stepped down from the position in July 2012. The conference, entitled “Cancer Epidemiology: From Pedigrees to Populations,” will highlight critical findings in cancer epidemiology from the last 50 years, as well as opportunities for future research directions. Long History of Leadership and Discovery

  9. LANSCE '90: The Manuel Lujan Jr. Neutron Scattering Center

    Energy Technology Data Exchange (ETDEWEB)

    Pynn, R.

    1990-01-01

    This paper describes progress that has been made at the Manuel Lujan Jr. Neutron Scattering Center (LANSCE) during the past two years. Presently, LANSCE provides a higher peak neutron flux than any other pulsed spallation neutron source. There are seven spectrometers for neutron scattering experiments that are operated for a national user program sponsored by the US Department of Energy. Two more spectrometers are under construction. Plans have been made to raise the number of beam holes available for instrumentation and to improve the efficiency of the target/moderator system. 9 refs., 4 figs.

  10. Martin Luther King, Jr., General Hospital and community involvement.

    Science.gov (United States)

    Humphrey, M M

    1973-07-01

    Community involvement is not just one facet of the new Martin Luther King, Jr., General Hospital's existence. It is the mainstream from which all other activities flow. In addition to meeting the conventional needs of a conventional hospital staff with the core collection of texts and journals, this library goes one step further. It acts as a resource for its community health workers, dietitians, and nurses in their various outreach programs. It serves as a stimulus for the high school or community college student who may be curious about a health career. It also finds time to provide reading material for its patients.

  11. Mancur Lloyd Olson, Jr. 1932-1998 Personal Recollections

    OpenAIRE

    Martin C McGuire

    1998-01-01

    This article memorializes the life and professional work of Mancur Lloyd Olson, Jr. The forty-two years of Mancur Olson's scholarly life were devoted to an inspiring pursuit of his vision of "macro." His ideas may occupy the core of macroeconomics fifty or one hundred years from now, or they may signify only one strand, but surely they will be present and influential in all future study of economics, of society and of interactions between them. Here in 1998, we don't know. But we do know that...

  12. Grid de datos desarrollo con AngularJS utilizando el patrón Modelo Vista-Controlador

    OpenAIRE

    García Salinero, Mario

    2014-01-01

    Angrid es un componente software para la web que se basa en la tecnología AngularJS. Esta herramienta permitirá a un desarrollador web crear regillas para la visualización de datos con muy poco esfuerzo. El modelo Vista-Controlador utilizado por AngularJS y los estándares web utilizados para este proyecto lo hacen perfecto para el desarrollo de aplicaciones web y manejo de datos JSON. Angrid is a software component for the web that is based on the AngularJS technology. This tool will allow...

  13. BioJS DAGViewer: A reusable JavaScript component for displaying directed graphs.

    Science.gov (United States)

    Kalderimis, Alexis; Stepan, Radek; Sullivan, Julie; Lyne, Rachel; Lyne, Michael; Micklem, Gos

    2014-01-01

    The DAGViewer BioJS component is a reusable JavaScript component made available as part of the BioJS project and intended to be used to display graphs of structured data, with a particular emphasis on Directed Acyclic Graphs (DAGs). It enables users to embed representations of graphs of data, such as ontologies or phylogenetic trees, in hyper-text documents (HTML). This component is generic, since it is capable (given the appropriate configuration) of displaying any kind of data that is organised as a graph. The features of this component which are useful for examining and filtering large and complex graphs are described. http://github.com/alexkalderimis/dag-viewer-biojs; http://github.com/biojs/biojs; http://dx.doi.org/10.5281/zenodo.8303.

  14. Measuring sequences of keystrokes with jsPsych: Reliability of response times and interkeystroke intervals.

    Science.gov (United States)

    Pinet, S; Zielinski, C; Mathôt, S; Dufau, S; Alario, F-X; Longcamp, M

    2016-07-13

    Although the precision and reliability of response time (RT) measurements performed via Web-based interfaces have been evaluated, sequences of keystrokes have never been investigated in detail. Keystrokes often occur in much more rapid succession than RTs, and operating systems may interpret successive or concomitant keyboard events according to both automatic and user-based settings. Sequence keystroke timing could thus be more sensitive than single RTs to noise in online measurements. Here, we quantified the precision and reliability of timing measures performed during sequences of keystrokes. We used the JavaScript jsPsych library to create an experiment involving finger-movement sequences, and ran it online with 633 participants. We manipulated the structure of three keystroke motor sequences, targeting a replication of previous findings regarding both RTs and interkeystroke intervals (IKIs). Our online data accurately reproduced the original results and allowed for a novel assessment of demographic variables such as age and gender. In parallel, we also measured the objective timing accuracy of the jsPsych interface by using specialized hardware and software, showing a constant 60-ms delay for RTs and a 0-ms delay for IKIs across the sequences. The distribution of IKIs revealed quantizing for a majority of participants, most likely due to the sampling frequency of their USB keyboards. Overall, these findings indicate that JsPsych provides good reliability and accuracy in sequence keystroke timings for mental chronometry purposes, through online recordings.

  15. phylo-node: A molecular phylogenetic toolkit using Node.js.

    Science.gov (United States)

    O'Halloran, Damien M

    2017-01-01

    Node.js is an open-source and cross-platform environment that provides a JavaScript codebase for back-end server-side applications. JavaScript has been used to develop very fast and user-friendly front-end tools for bioinformatic and phylogenetic analyses. However, no such toolkits are available using Node.js to conduct comprehensive molecular phylogenetic analysis. To address this problem, I have developed, phylo-node, which was developed using Node.js and provides a stable and scalable toolkit that allows the user to perform diverse molecular and phylogenetic tasks. phylo-node can execute the analysis and process the resulting outputs from a suite of software options that provides tools for read processing and genome alignment, sequence retrieval, multiple sequence alignment, primer design, evolutionary modeling, and phylogeny reconstruction. Furthermore, phylo-node enables the user to deploy server dependent applications, and also provides simple integration and interoperation with other Node modules and languages using Node inheritance patterns, and a customized piping module to support the production of diverse pipelines. phylo-node is open-source and freely available to all users without sign-up or login requirements. All source code and user guidelines are openly available at the GitHub repository: https://github.com/dohalloran/phylo-node.

  16. MILLS B. LANE, JR. AND ENTERPRISE IN A NEW SOUTH

    Directory of Open Access Journals (Sweden)

    Randall L. Patton

    2009-01-01

    Full Text Available For a century, Citizens & Southern Bank was a fixture in Georgia. In 1991, the C&S brand name disappeared in a merger with North Carolina National Bank. This was one of the bittersweet consequences of the slow, confusing swirl of bank deregulation after 1970, when institutions such as C&S simply disappeared, swallowed by the “winners” in the new competitive environment of interstate banking in the 1980s and 1990s. Even earlier, however, the Lane family had ceased to control the bank started by Mills Lane, Sr. in 1891. Mills B. Lane, Jr. was the last member of the Lane family to run C&S. After his retirement in 1973, Mills handpicked his successor and tried to retain some influence, but the bank began slipping away from the Lanes. By the early 80s, a decade before Hugh McColl’s NCNB acquired C&S, Mills Lane, Jr. was deeply alienated from the institution that had been, according to many, “Georgia’s cornerstone bank.”

  17. A new nearby PWN overlapping the Vela Jr SNR

    CERN Document Server

    Acero, F; Terrier, R; Renaud, M; Ballet, J

    2011-01-01

    PSR J0855-4644 is an energetic pulsar (Edot = 1.1x10^36 erg/s, P=65 ms) discovered near the South-East rim of the supernova remnant (SNR) RX J0852.0-4622 (aka Vela Jr) by the Parkes Multibeam Survey. The position of the pulsar is in spatial coincidence with an enhancement in X-rays and TeV gamma-rays, which could represent its pulsar wind nebula (PWN). We have revealed with an XMM-Newton observation the X-ray counterpart of the pulsar together with a surrounding extended emission thus confirming the suggestion of a PWN. The comparison of the absorption column density derived in X-rays from the pulsar with 12CO observations (tracing the dense gas) is used to derive an upper limit to the distance of the pulsar (d< 900 pc) and to discuss a possible association of the pulsar with the Vela Jr SNR. This new distance estimate implies that the pulsar is nearby and could therefore significantly contribute to the observed spectrum of cosmic-ray leptons (e-/e+).

  18. A new member of Brevidensovirus, 0507JS11 virus isolated from Culex mosquitoes collected in Xinjiang%新疆库蚊分离的0507JS11病毒为Brevidensovirus新成员

    Institute of Scientific and Technical Information of China (English)

    吕新军; 翟友刚; 孙肖红; 付士红; 王焕琴; 童苏祥; 张松; 梁国栋

    2009-01-01

    目的 揭示新疆库蚊分离的0507JS11病毒的基本特征,明确其分类地位.方法 对0507JS11病毒进行细胞感染特点观察、负染电子显微镜(简称电镜)观察、基因组核酸电泳检测、全基因序列测定和系统进化分析.结果 0507JS11病毒可以引起Aedes albopictus C6/36细胞病变;完整病毒颗粒呈20面立体对称,直径20 nm,无包膜;病毒基因组为长3977 nt的单股正链DNA,基因组核酸电泳检测呈大小约4 kbp的DNA条带;病毒基因组编码区包括3个开放读码框(open readingframe,ORF),ORF1和ORF2编码非结构蛋白(non-structural protein,NS),ORF3编码衣壳蛋白(capsidprotein,VP);全基因序列系统进化分析显示病毒位于Brevidensovirus内一个独立进化分支.结论 新疆库蚊分离的0507JS11病毒为Brevidensovirus新成员.%Objective To probe the primary characteristic of 0507JS11 virus isolated from Culex sp. and determine the classification of 0507JS11 virus in taxonomy. Methods 0507JS11 virus was cultured in Aedes albopictus C6/36 cells and cytopathic effects (CPEs) were recorded. Electro-microscopic morphology of 0507JS11 virus was observed. Total DNA extract of 0507JS11 virus was detected by 1% Agarose Gel Electrophoresis. Complete genomic sequence of 0507JS11 virus was sequenced and then made phylogenetie analysis. Results 0507JS11 virus could cause CPEs in Aedes albopictus C6/36 cells. Viral particles have no envelope and appear icosahedron symmetry with diameter of 20 nm. The genome of 0507JS11 virus was positive single strand DNA (ssDNA) with full length of 3977 nt. However, a DNA band about 4 kbp was observed in the electrophoresis of total DNA extract of 0507JS11 virus. The coding region of the genome included three ORFs, ORF1 and ORF2 code NSP1 and NSP2, ORF3 codes VP. Phylogenetic analysis of the complete genomic sequence of 0507JS11 virus indicated an independent linear in Brevidensovirus. Conclusion 0507JS11 virus is a new member in Brevidensovirus.

  19. Dosimetry of the JS-6500 industrial irradiator for the irradiation of the PVC graduated flasks; Dosimetria del irradiador industrial JS-6500 para la irradiacion de probetas de PVC

    Energy Technology Data Exchange (ETDEWEB)

    Castaneda F, A.; Carrasco A, H.; Martinez P, M.E. [Instituto Nacional de Investigaciones Nucleares, A.P. 18-1027, 11801 Mexico D.F. (Mexico)

    2002-07-01

    The dosimetry of the JS-6500 AECL irradiator was realized, outside of the industrial transportation rails to know the dose distribution, as well as its dose speed. This one with the intention of exposing to gamma radiation; plastified PVC graduated flasks and evaluating their interweavement or degradation or both. This study of dosimetry was carried out by means of a theoretical and experimental evaluation in air atmosphere. The results allow to know the irradiation conditions of the PVC graduated flasks as well as those results prove that has not a significant difference among the obtained result as theoretical as experimentally due to that the obtained result in the theoretical evaluation is 2.62 KGy/h and the result for the case of the experimental evaluation is 2.74 KGy/h. (Author)

  20. Roseomonas JS018有机磷农药降解酶的纯化%Purification of the organophosphorus pesticide degrading enzyme from Roseomonas JS018

    Institute of Scientific and Technical Information of China (English)

    江玉姬; 邓优锦; 刘新锐; 胡方平; 谢宝贵; 刘福阳; 黎志银

    2006-01-01

    本试验对能高效降解几种有机磷农药菌株JS018的降解酶进行分离和纯化.经分析该降解酶主要位于细胞间质,最适盐析硫酸铵饱和度为60%-70%,粗酶液经硫酸铵沉淀、Sephadex G-100凝胶过滤和DEAE-52柱层析得到较高纯度的酶液.通过SDS-PAGE电泳测定该酶相对分子质量约为37 ku,N末端16个氨基酸残基测序结果为:GAPFQNDVPPACYRFR.

  1. Research on Vibration and Noise of JS315 - type Reducer%JS315型减速机振动噪声的研究

    Institute of Scientific and Technical Information of China (English)

    王伟; 张亚琴

    2012-01-01

    齿轮箱的振动和噪声能够反映齿轮装置的品质,影响齿轮箱振动和噪声的因素有齿轮啮合、轴系变形、箱体精度以及安装误差等因素,其中齿轮啮合是主要因素,而齿轮的基节偏差和齿形偏差又是影响齿轮传动平稳性的主要因素.通过对公司JS315型减速机振动和噪声的研究,分析了影响齿轮箱振动和噪声的因素,找出了造成振动和异响的原因,成功解决了这一问题.%The vibration and noise of gearbox can reflect the quality of gear device, influence factors of gear box vibration and noise have the gearing mesh, shaft deformation, the gear case accuracy, installation error and so on, among which the gearing mesh is the major factor. The main factors which influence the stability of gear is gear base pitch deviation and the tooth profile deviation. Through the vibration and noise JS315 - type reducer, the influence factors of gear vibration and noise are analyzed,and the causes of abnormal sound and vibration are found out. The problem is successfully solved.

  2. Effects of JS-K, a novel anti-cancer nitric oxide prodrug, on gene expression in human hepatoma Hep3B cells.

    Science.gov (United States)

    Dong, Ray; Wang, Xueqian; Wang, Huan; Liu, Zhengyun; Liu, Jie; Saavedra, Joseph E

    2017-04-01

    JS-K is a novel anticancer nitric oxide (NO) prodrug effective against a variety of cancer cells, including the inhibition of AM-1 hepatoma cell growth in rats. To further evaluate anticancer effects of JS-K, human hepatoma Hep3B cells were treated with JS-K and the compound control JS-43-126 at various concentrations (0-100μM) for 24h, and cytotoxicity was determined by the MTS assay. The compound control JS-43-126 was not cytotoxic to Hep3B cells at concentrations up to 100μM, while the LC50 for JS-K was about 10μM. To examine the molecular mechanisms of antitumor effects of JS-K, Hep3B cells were treated with 1-10μM of JS-K for 24h, and then subjected to gene expression analysis via real time RT-PCR and protein immunostain via confocal images. JS-K is a GST-α targeting NO prodrug, and decreased immunostaining for GST-α was associated with JS-K treatment. JS-K activated apoptosis pathways in Hep3B cells, including induction of caspase-3, caspase-9, Bax, TNF-α, and IL-1β, and immunostaining for caspase-3 was intensified. The expressions of thrombospondin-1 (TSP-1) and the tissue inhibitors of metalloproteinase-1 (TIMP-1) were increased by JS-K at both transcript and protein levels. JS-K treatment also increased the expression of differentiation-related genes CD14 and CD11b, and depressed the expression of c-myc in Hep3B cells. Thus, multiple molecular events appear to be associated with anticancer effects of JS-K in human hepatoma Hep3B cells, including activation of genes related to apoptosis and induction of genes involved in antiangiogenesis and tumor cell migration. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  3. William T. Carpenter Jr: 35 years of clinical trials.

    Science.gov (United States)

    Buchanan, Robert W

    2014-03-01

    William T. Carpenter Jr has had a major impact on the design and conduct of clinical trials in schizophrenia. His contributions range from the decisive evaluation of the efficacy of hemodialysis to the development of novel approaches to evaluate new treatments for cognitive impairments and negative symptoms. He has developed innovative dosage reduction strategies. He has led efforts to focus drug development on those illness components that are not responsive to antipsychotic treatment. He has emphasized throughout his career the use of translational science to provide the conceptual framework for clinical trial interventions. This article reviews highlights of his many contributions, with an emphasis on 3 areas: (1) dosage reduction studies; (2) the use of the domains of psychopathology to identify drug development targets; and (3) the use of translational science to guide new drug development.

  4. Gino Marinuzzi Jr: Electronics and Early Multimedia Mentality in Italy

    Directory of Open Access Journals (Sweden)

    Maurizio Corbella

    2015-08-01

    Full Text Available In this essay I reassess the complexity of the convergence between electronic music and media practices in Rome in the 1950s and 1960s, through the reconstruction of the experience of composer Gino Marinuzzi Jr (1920-96. His engagement with technology as a structuring device of compositional processes is fundamental and inescapable, and brings to the fore crucial issues of ‘applied’ music’s troublesome reputation in the Italian cultural discourse. In reviewing Marinuzzi’s biography over the period 1949-75, my goal is to exemplify the key phases of this transitional period in Italian music history, in which technology, through the spreading of media and their increasing importance in cultural representations, came to constitute a new value of musical activity and at the same time renewed old questions concerning music’s aesthetic autonomy.

  5. PPI layouts: BioJS components for the display of Protein-Protein Interactions.

    Science.gov (United States)

    Salazar, Gustavo A; Meintjes, Ayton; Mulder, Nicola

    2014-01-01

    We present two web-based components for the display of Protein-Protein Interaction networks using different self-organizing layout methods: force-directed and circular. These components conform to the BioJS standard and can be rendered in an HTML5-compliant browser without the need for third-party plugins. We provide examples of interaction networks and how the components can be used to visualize them, and refer to a more complex tool that uses these components. http://github.com/biojs/biojs; http://dx.doi.org/10.5281/zenodo.7753.

  6. Implementation of CMS Central DAQ monitoring services in Node.js

    CERN Document Server

    Vougioukas, Michail

    2015-01-01

    This report summarizes my contribution to the CMS Central DAQ monitoring system, in my capacity as a CERN Summer Students Programme participant, from June to September 2015. Specifically, my work was focused on rewriting – from Apache/PHP to Node.js/Javascript - and optimizing real-time monitoring web services (mostly Elasticsearch-based but also some Oracle-based) for the CMS Data Acquisition (Run II Filterfarm). Moreover, it included an implementation of web server caching, for better scalability when simultaneous web clients use the services. Measurements confirmed that the software developed during this project has indeed a potential to provide scalable services.

  7. Applied Research of Node.js and MongoDb%Node.js 及 MongoDb 应用研究

    Institute of Scientific and Technical Information of China (English)

    李鹏

    2015-01-01

    Based on Node. js,a Customer Relationship Management System software was built with abundant library func-tions and helper functions to achieve high efficiency in the developing and testing. Then,it was used to set up a Customer Relationship Management(CRM)System for electric commercial enterprises,realizing the centralized management and sharing of customer information,namely,enterprise-style management of customer resources,to avoid the loss of cus-tomer resources and customer management blind spots generated due to changes resulting from business restructuring or personnel alteration. More importantly,the CRM,based on improved customer information,is able to support different customer-facing works to achieve full customer information sharing within the enterprise,improve the effectiveness and efficiency of customer-oriented tasks,therefore improving the overall customer satisfaction.%基于 Node.js 技术对客户关系管理系统进行搭建,设计出丰富的库函数和助手函数,以实现开发与测试的高效率。新构建的可供电商企业使用的客户关系管理系统(Customer Relationship Management System,CRM)能够实现对客户信息的集中管理和共享利用,即客户资源的企业化管理,避免因业务调整或人员变动造成的客户资源流失和客户管理盲区的产生;更重要是,CRM 可以基于完善的客户信息支持不同业务面向客户的工作,实现客户信息在企业内部的充分共享利用,提高面向客户工作的有效性和效率,从而全面提升客户的满意度。

  8. Claim on memory : a political biography of Franklin D. Roosevelt, Jr., 1914-1988

    NARCIS (Netherlands)

    Berg, Erik Eduard Willem van den

    2006-01-01

    This dissertation focuses on the political life of Franklin D. Roosevelt, Jr., the third surviving son of Franklin D. Roosevelt and Eleanor Roosevelt. The key question of this study emphasizes how FDR, Jr. interpreted the Roosevelt name and legacy during his life and political career. This book deal

  9. Connect the Book. Martin's Big Words: The Life of Dr. Martin Luther King, Jr.

    Science.gov (United States)

    Brodie, Carolyn S.

    2005-01-01

    In honor of Martin Luther King, Jr. Day, this month's featured book is "Martin's Big Words: The Life of Dr. Martin Luther King, Jr." The book was written by Doreen Rappaport and illustrated by Bryan Collier (Jump at the Sun, 2001. 40p. ISBN 0786807148). This pictorial biography of the world-renowned civil rights leader has one of the most striking…

  10. 78 FR 57105 - Wm. Wrigley Jr. Company; Filing of Color Additive Petition

    Science.gov (United States)

    2013-09-17

    ... HUMAN SERVICES Food and Drug Administration 21 CFR Part 73 Wm. Wrigley Jr. Company; Filing of Color.... Wrigley Jr. Company, proposing that the color additive regulations be amended to expand the use of... lower the specification limit ] for lead in synthetic iron oxide for human food use. DATES: The...

  11. Exploring Three-js library possibilitiesfor the dissemination of cultural heritage projects

    Directory of Open Access Journals (Sweden)

    Jesús Palomar-Vazquez

    2016-11-01

    Full Text Available For whatever project related with the study and conservation of cultural heritage, the dissemination stage of tree-dimensional (3D information must be a key part of the whole process. Most of the existing web-based platforms are using WebGL technology to disseminate 3D content through Web navigators, despite they are normally generic, with a low level of viewers ‘customization. Alternatively, users can make use of several libraries, most of them open source, which allow a complete adaptation to the specific project features, even though enough level of programming skills are necessary to use them. In the present paper we will describe the minimum requirements that any cultural heritage dissemination project should contain and its implementation using Three-js, one of the most versatile open source libraries for 3D visualization. In addition, we will show several examples of Three-js integration with other libraries that take advantage from HTML5 (HyperText Markup Language, version 5 to enhance the user's experience on a Web platform.

  12. Projektový management v prostředí ExtJS

    OpenAIRE

    Zajíc, Jiří

    2010-01-01

    Tato bakalářská práce je zaměřena na management projektů pomocí Ganttových diagramů. Problematika je řešena jako klient-server aplikace postavená na knihovně ExtJS. Práce nastiňuje možnosti ExtJS a přináší detailní popis Ganttova diagramu. Z něj vychází návrh systému, který se týká hlavně principu vytváření diagramu, způsobu jeho chování a drag&drop operací sloužících pro jeho úpravu. Podle návrhu je následně zpracována implementace, která je zde detailně popsána. This bachelor's thes...

  13. Activation of Pathogenesis-related Genes by the Rhizobacterium, Bacillus sp. JS, Which Induces Systemic Resistance in Tobacco Plants

    Directory of Open Access Journals (Sweden)

    Ji-Seong Kim

    2015-06-01

    Full Text Available Plant growth promoting rhizobacteria (PGPR are known to confer disease resistance to plants. Bacillus sp. JS demonstrated antifungal activities against five fungal pathogens in in vitro assays. To verify whether the volatiles of Bacillus sp. JS confer disease resistance, tobacco leaves pre-treated with the volatiles were damaged by the fungal pathogen, Rhizoctonia solani and oomycete Phytophthora nicotianae. Pre-treated tobacco leaves had smaller lesion than the control plant leaves. In pathogenesis-related (PR gene expression analysis, volatiles of Bacillus sp. JS caused the up-regulation of PR-2 encoding β-1,3-glucanase and acidic PR-3 encoding chitinase. Expression of acidic PR-4 encoding chitinase and acidic PR-9 encoding peroxidase increased gradually after exposure of the volatiles to Bacillus sp. JS. Basic PR-14 encoding lipid transfer protein was also increased. However, PR-1 genes, as markers of salicylic acid (SA induced resistance, were not expressed. These results suggested that the volatiles of Bacillus sp. JS confer disease resistance against fungal and oomycete pathogens through PR genes expression.

  14. Obituary: Timothy P. McCullough, Jr., 1910-2004

    Science.gov (United States)

    McCullough, Charles

    2007-12-01

    Timothy Pendleton McCullough Jr., 93, a retired research physicist who was a pioneer in the measurement of microwave radiation from planetary surfaces, died of cardiac arrest on 19 November 2004, at Inova Fairfax Hospital. He lived in Springfield, VA. McCullough, who was principally a radio astronomer, published 22 scientific research papers while working in the Atmosphere and Astrophysics Division of NRL, from 1946 until his retirement in 1975. He spent the early part of his career in planetary observation and was among the first in his field to use radio astronomy to measure the surface temperature of Venus. He also studied Mars and Jupiter. Later, his interest turned to supernovas, galaxies and solar flares. He was an emeritus member of the American Astronomical Society and a member of the Sigma Xi Scientific Research Society. McCullough was born on 9 December 1910 in Vardaman, Mississippi. His father, Timothy P. McCullough, was a farmer and bookkeeper. His mother, Annie W. McCullough, was a homemaker. Timothy McCullough, Jr.'s parents, as well as two sisters and a brother, are deceased. McCullough graduated from the University of Mississippi in Oxford in 1936 and received a master's degree in physics from North Carolina State University in Raleigh. He taught physics and aviation navigation before entering the Navy during World War II. He instructed Russian sailors on anti-submarine warfare. McCullough left the Navy at the end of the war, but continued to serve in the Naval Reserve. He was recalled to active duty during the Korean War and was stationed at Potomac River Naval Command, where he wrote technical documents on electronic warfare systems. McCullough retired from the Naval Reserve in 1969 with the rank of commander. He was a charter member of First Baptist Church in Springfield and a former deacon and Sunday school teacher at First Baptist Church in Alexandria. Survivors include his wife of 63 years, Virginia Ball McCullough of Springfield; three

  15. JS-K, a nitric oxide pro-drug, regulates growth and apoptosis through the ubiquitin-proteasome pathway in prostate cancer cells.

    Science.gov (United States)

    Tan, Guobin; Qiu, Mingning; Chen, Lieqian; Zhang, Sai; Ke, Longzhi; Liu, Jianjun

    2017-05-26

    In view of the fact that JS-K might regulate ubiquitin E3 ligase and that ubiquitin E3 ligase plays an important role in the mechanism of CRPC formation, the goal was to investigate the probable mechanism by which JS-K regulates prostate cancer cells. Proliferation inhibition by JS-K on prostate cancer cells was examined usingCCK-8 assays. Caspase 3/7 activity assays and flow cytometry were performed to examine whether JS-K induced apoptosis in prostate cancer cells. Western blotting and co-immunoprecipitation analyses investigated JS-K's effects on the associated apoptosis mechanism. Real time-PCR and Western blotting were performed to assess JS-K's effect on transcription of specific AR target genes. Western blotting was also performed to detect Siah2 and AR protein concentrations and co-immunoprecipitation to detect interactions of Siah2 and AR, NCoR1 and AR, and p300 and AR. JS-K inhibited proliferation and induced apoptosis in prostate cancer cells. JS-K increased p53 and Mdm2 concentrations and regulated the caspase cascade reaction-associated protein concentrations. JS-K inhibited transcription of AR target genes and down-regulated PSA protein concentrations. JS-K inhibited Siah2 interactions and also inhibited the ubiquitination of AR. With further investigation, JS-K was found to stabilize AR and NCoR1 interactions and diminish AR and p300 interactions. The present results suggested that JS-K might have been able to inhibit proliferation and induce apoptosis via regulation of the ubiquitin-proteasome degradation pathway, which represented a promising platform for the development of new compounds for PCa treatments.

  16. The renaissance man of burn surgery: Basil A. Pruitt Jr.

    Science.gov (United States)

    Capek, Karel D; Foncerrada, Guillermo; Clayton, R Patrick; Sljivich, Michaela; Voigt, Charles D; Hundeshagen, Gabriel; Cambiaso-Daniel, Janos; Porter, Craig; Guillory, Ashley; Herndon, David N

    2017-07-08

    Dr. Basil A. Pruitt Jr., a consummate clinical and translational surgeon-scientist, has been spent over half a century at the forefront of an advancing standard of burn care. Commanding the US Army Institute for Surgical Research in San Antonio, he trained generations of leading burn clinicians and allied scientists. At his direction, there were forged discoveries in resuscitation from shock, treatment of inhalation injury, control of burn-related infections, prevention of iatrogenic complications, and understanding the sympathetic, endocrine, and immune responses to burn injury. Most consequentially, this team was among the first recognize and define alterations in the basal metabolic rate and thermoregulation consequent to burn injury. These investigations prompted groundbreaking insights into the coordinated nervous, autonomic, endocrine, immune, and metabolic outflows that a severely-burned patient uses to remain alive and restore homeostasis. Marking his scientific consequence, many of his reports continue bear fruit when viewed through a contemporary lens. This paper summarizes some of the major findings of his career thus far, and is intended to complement a Festschrift recently held in his honor. Not applicable.

  17. John Call Dalton, Jr., MD: America's first neurophysiologist.

    Science.gov (United States)

    Fine, E J; Manteghi, T; Sobel, S H; Lohr, L A

    2000-09-26

    Before the discoveries of John Call Dalton, Jr., MD (1824-1889), innervation of laryngeal muscles, long-term effects of cerebellar lesions, and consequences of raised intracranial pressure were poorly understood. Dalton discovered that the posterior cricoarytenoid muscles adducted the vocal cords during inspiration. He confirmed Flourens' observations that acute ablation of the cerebellum of pigeons caused loss of coordination. Dalton observed that properly cared for pigeons gradually recovered "coordinating power." Dalton observed that prolonged raised intracranial pressure caused tachycardia and then fatal bradycardia in dogs. Before Dalton published his photographic atlas of the human brain, neuroanatomy atlases were sketched by Europeans and imported into the United States. Dalton's atlas of the human brain contained precise photographs of vertical and horizontal sections that equal modern works. Before Dalton introduced live demonstrations of animals, physiology was taught by recitation of texts only. Dalton was the first American-born professor to teach physiology employing demonstrations of live animals operated on under ether anesthesia. He wrote an essay advocating experimentation on animals as the proper method of acquiring knowledge of function and that humane animal experimentation would ultimately improve the health of man and animals. His eloquent advocacy for humane experimental physiology quelled attacks by contemporaneous antivivisectionists. Dalton was America's first experimental neurophysiologist.

  18. East Weddell Sea echinoids from the JR275 expedition

    Directory of Open Access Journals (Sweden)

    Thomas Saucède

    2015-05-01

    Full Text Available Information regarding the echinoids in this dataset is based on the Agassiz Trawl (AGT and epibenthic sledge (EBS samples collected during the British Antarctic Survey cruise JR275 on the RRS James Clark Ross in the austral summer 2012. A total of 56 (1 at the South Orkneys and 55 in the Eastern Weddell Sea Agassiz Trawl and 18 (2 at the South Orkneys and 16 in the Eastern Weddell Sea epibenthic sledge deployments were performed at depths ranging from ~280 to ~2060 m. This presents a unique collection for the Antarctic benthic biodiversity assessment of an important group of benthic invertebrates. In total 487 specimens belonging to six families, 15 genera, and 22 morphospecies were collected. The species richness per station varied between one and six. Total species richness represents 27% of the 82 echinoid species ever recorded in the Southern Ocean (David et al. 2005b, Pierrat et al. 2012, Saucède et al. 2014. The Cidaridae (sub-family Ctenocidarinae and Schizasteridae are the two most speciose families in the dataset. They comprise seven and nine species respectively. This is illustrative of the overall pattern of echinoid diversity in the Southern Ocean where 65% of Antarctic species belong to the families Schizasteridae and Cidaridae (Pierrat et al. 2012.

  19. 2015 AMCA Memorial Lecture Honoree: Dr. Richard Floyd Darsie, Jr.

    Science.gov (United States)

    Day, Jonathan F

    2015-12-01

    Richard Floyd Darsie, Jr. (1915-2014) is the 2015 American Mosquito Control Association Memorial Lecture Honoree. He was one of the greatest mosquito taxonomists of the 20th century and died peacefully on April 10, 2014, in Grove City, PA, at the age of 99 after a professional career that spanned eight decades. Dick's broad areas of interest and training made him a versatile scientist, teacher, and researcher. His intense interest in adult and immature mosquito morphology and taxonomy, as well as mosquito distribution and bionomics, started early in his career at two early academic postings: Franklin and Marshall College (1949-54) and the University of Delaware (1954-62). Dick would take his mosquito interests with him to postings and research projects around the world: Nepal, the Philippines, Atlanta, El Salvador, Guatemala, Fort Collins, South Carolina, Argentina, and Florida. His travels and studies would make him an international expert on mosquito taxonomy. Dick's legacy lives on in the hundreds of students from across the globe who learned mosquito identification skills from this world-renowned mosquito taxonomist. All will proudly profess that, "I learned mosquito identification from Dr. Darsie." And that is all that is needed to prove one's credentials in the field, learning the art from the best there is.

  20. Mattson Solomon transform and algebra codes

    DEFF Research Database (Denmark)

    Martínez-Moro, E.; Benito, Diego Ruano

    2009-01-01

    In this note we review some results of the first author on the structure of codes defined as subalgebras of a commutative semisimple algebra over a finite field (see Martínez-Moro in Algebra Discrete Math. 3:99-112, 2007). Generator theory and those aspects related to the theory of Gröbner bases...

  1. Phylogeny and physiology of candidate phylum 'Atribacteria' (OP9/JS1) inferred from cultivation-independent genomics.

    Science.gov (United States)

    Nobu, Masaru K; Dodsworth, Jeremy A; Murugapiran, Senthil K; Rinke, Christian; Gies, Esther A; Webster, Gordon; Schwientek, Patrick; Kille, Peter; Parkes, R John; Sass, Henrik; Jørgensen, Bo B; Weightman, Andrew J; Liu, Wen-Tso; Hallam, Steven J; Tsiamis, George; Woyke, Tanja; Hedlund, Brian P

    2016-02-01

    The 'Atribacteria' is a candidate phylum in the Bacteria recently proposed to include members of the OP9 and JS1 lineages. OP9 and JS1 are globally distributed, and in some cases abundant, in anaerobic marine sediments, geothermal environments, anaerobic digesters and reactors and petroleum reservoirs. However, the monophyly of OP9 and JS1 has been questioned and their physiology and ecology remain largely enigmatic due to a lack of cultivated representatives. Here cultivation-independent genomic approaches were used to provide a first comprehensive view of the phylogeny, conserved genomic features and metabolic potential of members of this ubiquitous candidate phylum. Previously available and heretofore unpublished OP9 and JS1 single-cell genomic data sets were used as recruitment platforms for the reconstruction of atribacterial metagenome bins from a terephthalate-degrading reactor biofilm and from the monimolimnion of meromictic Sakinaw Lake. The single-cell genomes and metagenome bins together comprise six species- to genus-level groups that represent most major lineages within OP9 and JS1. Phylogenomic analyses of these combined data sets confirmed the monophyly of the 'Atribacteria' inclusive of OP9 and JS1. Additional conserved features within the 'Atribacteria' were identified, including a gene cluster encoding putative bacterial microcompartments that may be involved in aldehyde and sugar metabolism, energy conservation and carbon storage. Comparative analysis of the metabolic potential inferred from these data sets revealed that members of the 'Atribacteria' are likely to be heterotrophic anaerobes that lack respiratory capacity, with some lineages predicted to specialize in either primary fermentation of carbohydrates or secondary fermentation of organic acids, such as propionate.

  2. Desarrollo del Front-End de una aplicación web con el framework EXT JS 5

    OpenAIRE

    Carrero Salcedo, Enrique

    2015-01-01

    Este trabajo de fin de grado trata sobre el desarrollo de una aplicación web utilizando uno de los frameworks de JavaScript más potentes del mercado, el EXT JS5. Este ha sido desarrollado por Sencha. La memoria está dividida en 9 capítulos, en los cuales se explican los conocimientos básicos que un desarrollador debe tener para comenzar a utilizar el EXT JS 5; las ventajas y los contras de este framework respecto a otros; una descripción general de cómo desarrollar el Front-End de una apli...

  3. 78 FR 25942 - J.R. Simplot Co.; Availability of Petition for Determination of Nonregulated Status of Potato...

    Science.gov (United States)

    2013-05-03

    ... Animal and Plant Health Inspection Service J.R. Simplot Co.; Availability of Petition for Determination... petition from the J.R. Simplot Company (Simplot) seeking a determination of nonregulated status of potatoes... Petition Number 13-022-01p) from the J.R. Simplot Company (Simplot) of Boise, ID, seeking a...

  4. Lonnie R. Snowden Jr.: Award for Distinguished Contributions to Research in Public Policy.

    Science.gov (United States)

    2014-11-01

    The Award for Distinguished Contributions to Research in Public Policy is given to a psychologist who has made a distinguished empirical and/or theoretical contribution to research in public policy, either through a single extraordinary achievement or a lifetime of work. The 2014 recipient of this award is Lonnie R. Snowden Jr. "Over the past several decades, Lonnie R. Snowden Jr. has systematically built a research agenda on the financing and organization of mental health services that has driven much of our current health policy reform efforts." Snowden Jr.'s award citation, biography, and a selected bibliography are presented here. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  5. Assessment of J-R Curves Obtained from Precracked Charpy Samples

    Science.gov (United States)

    1985-09-01

    16 3. J-R curves for A723, Class 1, Grade 4 pressure vessel steel . 17 4. J-R curves for HY80 steel . 18 5. J-R curves for HY130 steel . 19 DTIC t,. 1 NV...In HY80 and KY130 steels , it is clear that significant strain-hardening occurred. The effect of strain-hardening could be crack growth at peak load...aimmoSO ff nwoa MW Identify b black nrnmsbm’) 3-R curves were determined for five materials (7075-T651; 2024-T351; HY13O; HY80 ; and A723, Class 1

  6. William D. Harper, Jr, MS, DC: anything can cause anything.

    Science.gov (United States)

    Keating, Joseph C

    2008-03-01

    Trained as an engineer and a chiropractor, William D. Harper, Jr. made his career in the healing arts as instructor, writer and president of the Texas Chiropractic College (TCC). A native of Texas who grew up in various locales in the Lone Star State, in Mexico and in the Boston area, he took his bachelor's and master's degree in engineering in 1933 and 1934 from the Massachusetts Institute of Technology, and his chiropractic degree at TCC in 1942. Dissatisfied with the "foot-on-the-hose" concept of subluxation syndrome (D.D. Palmer's second theory), Dr. Harper studied and wrote about aberrant neural irritation as an alternative explanation for disease and for the broad clinical value he perceived in the chiropractic art. In this he paralleled much of D.D. Palmer's third theory of chiropractic. His often reprinted textbook, Anything Can Cause Anything, brought together much of what he had lectured and written about in numerous published articles. He was well prepared for the defense of chiropractic that he offered in 1965 in the trial of the England case in federal district court in Louisiana. The case was lost when the court ruled that the legislature rather than the judiciary should decide whether to permit chiropractors to practice, but Harper's performance was considered excellent. He went on to guide the TCC as president from 1965 through 1976, its first 11 years after relocating from San Antonio to Pasadena, Texas. Harper built the school - its faculty, staff and facilities - from very meager beginnings to a small but financially viable institution when he departed. Along the way he found fault with both chiropractic political camps that vied for federal recognition as the accrediting agency for chiropractic colleges in the United States. Dr. Bill Harper was a maverick determined to do things his way, and in many respects he was successful. He left a mark on the profession that merits critical analysis.

  7. Lynn White Jr. and the greening-of-religion hypothesis.

    Science.gov (United States)

    Taylor, Bron; Van Wieren, Gretel; Zaleha, Bernard Daley

    2016-10-01

    Lynn White Jr.'s "The Historical Roots of Our Ecologic Crisis," which was published in Science in 1967, has played a critical role in precipitating interdisciplinary environmental studies. Although White advances a multifaceted argument, most respondents focus on his claim that the Judeo-Christian tradition, especially Christianity, has promoted anthropocentric attitudes and environmentally destructive behaviors. Decades later, some scholars argue contrarily that Christianity in particular and the world's predominant religions in general are becoming more environmentally friendly, known as the greening-of-religion hypothesis. To test these claims, we conducted a comprehensive review of over 700 articles-historical, qualitative, and quantitative-that are pertinent to them. Although definitive conclusions are difficult, we identified many themes and dynamics that hinder environmental understanding and mobilization, including conservative theological orientations and beliefs about the role of divine agency in preventing or promoting natural events, whether the religion is an Abrahamic tradition or originated in Asia. On balance, we found the thrust of White's thesis is supported, whereas the greening-of-religion hypothesis is not. We also found that indigenous traditions often foster proenvironmental perceptions. This finding suggests that indigenous traditions may be more likely to be proenvironmental than other religious systems and that some nature-based cosmologies and value systems function similarly. Although we conclude White's thesis and subsequent claims are largely born out, additional research is needed to better understand under what circumstances and communication strategies religious or other individuals and groups may be more effectively mobilized to respond to contemporary environmental challenges. © 2016 Society for Conservation Biology.

  8. Kekule.js: An Open Source JavaScript Chemoinformatics Toolkit.

    Science.gov (United States)

    Jiang, Chen; Jin, Xi; Dong, Ying; Chen, Ming

    2016-06-27

    Kekule.js is an open-source, object-oriented JavaScript toolkit for chemoinformatics. It provides methods for many common tasks in molecular informatics, including chemical data input/output (I/O), two- and three-dimensional (2D/3D) rendering of chemical structure, stereo identification, ring perception, structure comparison, and substructure search. Encapsulated widgets to display and edit chemical structures directly in web context are also supplied. Developed with web standards, the toolkit is ideal for building chemoinformatics applications over the Internet. Moreover, it is highly platform-independent and can also be used in desktop or mobile environments. Some initial applications, such as plugins for inputting chemical structures on the web and uses in chemistry education, have been developed based on the toolkit.

  9. Report on the side-effects of Pharmacopuncture Lubricants(CF, JsD

    Directory of Open Access Journals (Sweden)

    Jong Young, Lee

    2007-12-01

    Full Text Available Objectives : This study aims to report inflammatory reactions of Pharmacopuncture lubricants (CF and JsD when administered on GB21, GB20, and TE23 in clinical trials. Methods : Follow-up studies were made on each patient's clinical observation and specific managemen. Results : 1. Inflammation induced by pharmacopuncture lubricants were limited to local area of administration. 2. Intensity of inflammation was depended on the patient's condition. 3. Inflammation caused pain, skin flare, and discomfort on the patient. Inflammation subsided when dissipating technique was rendered with the conventional acupuncture needle. Conclusions : It appears that prolonged usage of pharmacopuncture lubricant on the specific point can induce inflammation, thus using alternative pharmacopuncture is recommended.

  10. Mobilā lietotne: "Instagram bilžu plānotājs"

    OpenAIRE

    Cibuļskis, Aigars

    2016-01-01

    Šajā dokumentā ir iekļauta Latvijas Universitātes Datorikas fakultātes kursa “Kvalifikācijas darbs II” (DatZ2049) praktiskā darba ietvaros izstrādātā lietotne “Mobila lietotne “Instagram bilžu plānotājs”” tehniskā dokumentācija, kas ietver programmatūras prasību specifikāciju, datu bāzes un ekrānformu projektējumus. Instagram bilžu plānotājs - ir lietotne Android platformai, kura domāta atvieglot bilžu izlikšanu sociālajā tīklā Instagram, modes blogeriem un mā...

  11. Obituary: Raymond Edwin White Jr., 1933-2004

    Science.gov (United States)

    Liebert, James William

    2004-12-01

    Raymond E. White, Jr., died unexpectedly at his home, in the early morning hours of October 12, 2004. Death appears to have been caused by severe diabetic shock. He retired from the Department of Astronomy/Steward Observatory in July 1999 with the title of University Distinguished Professor, after serving on the faculty of this institution for over 35 years. He was born in Freeport, Illinois, on 6 May 1933, to Beatrice and Raymond E, Sr. -the latter being a career soldier in the US Army. Ray's early schooling took place in Illinois, New Jersey, Germany and Switzerland, following his father's assignments. He obtained a bachelors degree from the University of Illinois in 1955. Next Ray enlisted in the US Army, but quickly was enrolled in Officer Candidate School. He then served as lst Lt. in the US Army Corps of Engineers. Although military affairs remained a lifelong interest, and he was a member of the Company of Military Historians, Ray decided after three years to return to academia. He entered the astronomy PhD program at the University of Illinois in 1958. His PhD dissertation was supervised by Ivan R. King. Ray accepted a faculty position at the University of Arizona in 1964. First and foremost, Ray White was known at Arizona as an excellent teacher, revered by a large number of former students. When the astronomy major program was begun in 1967, Ray was one of three, original, major advisors. Over the next three decades, he was a leader at the University level in reforming the undergraduate program and courses. He was selected Outstanding University Faculty Member in April 1989 and he served as one of a handful of professors who are Faculty Fellows. These Fellows devote untold hundreds of hours as part-time residents at student dormitories, to give students a friendly face to address their problems. In 1995, Ray was among the first group of faculty to be recognized as University Distinguished Professors. In the year of his retirement, 1999, University

  12. Obituary: Edward W. Burke, Jr. (1924-2011)

    Science.gov (United States)

    Bloomer, Raymond, Jr.

    2011-12-01

    Dr. Edward W. Burke Jr. passed away on June 15, 2011, after suffering a heart attack. Dr. Burke devoted his professional life to the research and teaching of physics and astronomy at King College in Bristol, Tennessee. Edward W. Burke, Jr., was born in Macon, Georgia, on September 16, 1924. He was a Navy veteran, having been commissioned as an ensign in 1944. He served in the Pacific near the end of World War II. He proceeded to complete his undergraduate degree in mathematics from Presbyterian College in 1947 and pursued the M.S. and Ph.D. in physics (1949 and 1954, respectively) at the University of Wisconsin. Under the direction of Professor Julian Mack, his thesis was titled "Isotope Shift in the Spectra of Boron." Although he did research in atomic spectra in the early part of his career, his interest in astronomy and variable stars in particular were his primary interests during his long academic career. Dr. Burke began his illustrious career at King College in 1949. He initiated the astronomy program there in 1950, included constructing a 12.5 inch Newtonian telescope, homemade as was most everything in those days. Many of his students learned about photometry at the Burke Observatory on the college campus. Burke was known for his trips to the Kitt Peak and Lowell observatories accompanied by undergraduate students on his trips, all of which were made by automobile which he preferred over flying. His initial interest in Ap stars later broadened into variable and especially eclipsing binary stars. His motivation was maintained by his desire to have his students experience basic research and to spark their interest in advanced degrees. Numerous students achieved advanced science and medical degrees because of Burke's encouragement and mentoring. In 1959, Dr. Burke was awarded a Fulbright professorship and traveled to Chile where he taught physics for a year in the Engineering School at the University of Chile in Santiago. He worked to establish a physics

  13. SITE TECHNOLOGY CAPSULE: J.R. SIMPLOT EX-SITU BIOREMEDIATION TECHNOLOGY: DINOSEB

    Science.gov (United States)

    The J.R. Simplot Ex-Situ Bioremediation Technology is designed to anaerobically degrade nitroaromatic and energetic compounds in soils and liquids without forming identifiable toxic intermediate compounds produced by other biotreatment methods. This technology was evaluated un...

  14. Week-long celebration of Dr. Martin Luther King Jr. legacy continues

    OpenAIRE

    Owczarski, Mark

    2006-01-01

    A wide range of educational and cultural programs and community service events are underway as Virginia Tech celebrates Dr. Martin Luther King Jr. Week Jan. 15-20. All events are free (unless otherwise noted) and open to the public.

  15. Leo Piilonen appointed William E. Hassinger, Jr. Senior Faculty Fellow in Physics

    OpenAIRE

    Owczarski, Mark

    2010-01-01

    Leo Piilonen, professor of physics in the College of Science at Virginia Tech, was recently appointed the William E. Hassinger, Jr., Senior Faculty Fellow in Physics by the Virginia Tech Board of Visitors.

  16. Maya Angelou to speak during Virginia Tech's third annual Martin Luther King Jr. celebration

    OpenAIRE

    Williams, Meghan

    2008-01-01

    A remarkable woman who is hailed as one of the greatest voices of contemporary literature, Maya Angelou, will be a guest speaker during the third annual Dr. Martin Luther King Jr. celebration at Virginia Tech.

  17. Maya Angelou to visit Virginia Tech during third annual Martin Luther King, Jr. celebration

    OpenAIRE

    Williams, Meghan

    2007-01-01

    A remarkable woman who is hailed as one of the greatest voices of contemporary literature, Maya Angelou, will be a guest speaker during the third annual Dr. Martin Luther King Jr. celebration at Virginia Tech.

  18. Weather from 250 Miles Up: Visualizing Precipitation Satellite Data (and Other Weather Applications) Using CesiumJS

    Science.gov (United States)

    Lammers, Matt

    2017-01-01

    Geospatial weather visualization remains predominately a two-dimensional endeavor. Even popular advanced tools like the Nullschool Earth display 2-dimensional fields on a 3-dimensional globe. Yet much of the observational data and model output contains detailed three-dimensional fields. In 2014, NASA and JAXA (Japanese Space Agency) launched the Global Precipitation Measurement (GPM) satellite. Its two instruments, the Dual-frequency Precipitation Radar (DPR) and GPM Microwave Imager (GMI) observe much of the Earth's atmosphere between 65 degrees North Latitude and 65 degrees South Latitude. As part of the analysis and visualization tools developed by the Precipitation Processing System (PPS) Group at NASA Goddard, a series of CesiumJS [Using Cesium Markup Language (CZML), JavaScript (JS) and JavaScript Object Notation (JSON)] -based globe viewers have been developed to improve data acquisition decision making and to enhance scientific investigation of the satellite data. Other demos have also been built to illustrate the capabilities of CesiumJS in presenting atmospheric data, including model forecasts of hurricanes, observed surface radar data, and gridded analyses of global precipitation. This talk will present these websites and the various workflows used to convert binary satellite and model data into a form easily integrated with CesiumJS.

  19. Biodegradation of isoproturon using a novel Pseudomonas aeruginosa strain JS-11 as a multi-functional bioinoculant of environmental significance.

    Science.gov (United States)

    Dwivedi, Sourabh; Singh, Braj Raj; Al-Khedhairy, Abdulaziz A; Musarrat, Javed

    2011-01-30

    Biodegradation of phenylurea herbicide isoproturon was studied in soil microcosm bioaugmented with a novel bacterial strain JS-11 isolated from wheat rhizosphere. The molecular characterization based on 16SrDNA sequence homology confirmed its identity as Pseudomonas aeruginosa strain JS-11. The herbicide was completely degraded within 20 days at ambient temperature with the rate constant of 0.08 day(-1), following the first-order rate kinetics. In stationary phase, at a cell density of 6.5 × 10(9) CFU mL(-1), the bacteria produced substantially increased amounts of indole acetic acid (IAA) in the presence of tryptophan as compared with the control. Also, the bacteria exhibited a time-dependent increase in the amount of tri-calcium phosphate solubilization in Pikovskaya's medium. Further screening of the strain JS-11 for auxiliary activities revealed its remarkable capability of producing the siderophores and hydrogen cyanide (HCN), besides antifungal activity against a common phytopathogen Fusarium oxysporum. Thus, the versatile P. aeruginosa strain JS-11 with innate potential for multifarious biological activities is envisaged as a super-bioinoculant for exploitation in the integrated bioremediation, plant growth and disease management (IBPDM) in contaminated agricultural soils.

  20. SN 2009js at the crossroads between normal and subluminous Type IIP supernovae: optical and mid-infrared evolution

    CERN Document Server

    Gandhi, P; Tanaka, M; Nozawa, T; Kawabata, K S; Saviane, I; Maeda, K; Moriya, T J; Hattori, T; Sasada, M; Itoh, R

    2013-01-01

    We present a study of SN 2009js in NGC 918. Multi-band Kanata optical photometry covering the first ~120 days show the source to be a Type IIP SN. Reddening is dominated by that due to our Galaxy. One-year-post-explosion photometry with the NTT, and a Subaru optical spectrum 16 days post-discovery, both imply a good match with the well-studied subluminous SN 2005cs. The plateau phase luminosity of SN 2009js and its plateau duration are more similar to the intermediate luminosity IIP SN 2008in. Thus, SN 2009js shares characteristics with both subluminous and intermediate luminosity SNe. Its radioactive tail luminosity lies between SN 2005cs and SN 2008in, whereas its quasi-bolometric luminosity decline from peak to plateau (quantified by a newly-defined parameter Delta[logL] measuring adiabatic cooling following shock breakout) is much smaller than both the others. We estimate the ejected mass of 56Ni to be low (~0.007 Msun). The SN explosion energy appears to have been small, similar to SN 2005cs. SN 2009js i...

  1. Complete Genome Sequence of Streptococcus pyogenes emm14 JS95, a Necrotizing Fasciitis Strain Isolated in Israel

    Science.gov (United States)

    Chee, Jacqueline L. Y.; Ravins, Miriam; Hanski, Emanuel

    2017-01-01

    ABSTRACT Here, we report the complete genome sequence of the Streptococcus pyogenes emm14 strain JS95, isolated from a patient with necrotizing fasciitis. The streptococcal invasion locus (sil), the first quorum-sensing system characterized in S. pyogenes, was identified in this strain. PMID:28302774

  2. Case report: massive postpartum transfusion of Jr(a+) red cells in the presence of anti-Jra.

    Science.gov (United States)

    Yuan, S; Armour, R; Reid, A; Abdel-Rahman, K F; Rumsey, D M; Phillips, M; Nester, T

    2005-01-01

    Jr(a) is a high-prevalence antigen. The rare Jr(a-) individuals can form anti-Jr(a) after exposure to the Jr(a) antigen through transfusion or pregnancy. The clinical significance of anti-Jr(a) is not well established. This study reports a case of a 31-year-old woman with a previously identified anti-Jr(a) who required massive transfusion of RBCs after developing life-threatening postpartum disseminated intravascular coagulopathy. Despite the emergent transfusion of 15 units of Jr(a) untested RBCs, she did not develop laboratory or clinical evidence of acute hemolysis. The patient's anti-Jr(a) had a pretransfusion titer of 4 and a monocyte monolayer assay (MMA) reactivity of 68.5% (reactivity > 5% is considered capable of shortening the survival of incompatible RBCs). The titer increased fourfold to 64 and the MMA reactivity was 72.5% on Day 10 posttransfusion. Review of laboratory data showed evidence of a mild delayed hemolytic transfusion reaction by Day 10 posttransfusion. Despite rare reports of hemolytic transfusion reactions due to anti-Jr(a) in the literature, most cases, including this one, report that this antibody is clinically insignificant or causes only mild delayed hemolysis. Clinicians should be advised to balance the risks of withholding transfusion with the small chance of significant hemolysis after transfusion of Jr(a+) RBCs in the presence of anti-Jr(a).

  3. Magnetoplasmadynamcis - Portrait of Macon C. 'Mike' Ellis, Jr

    Science.gov (United States)

    1962-01-01

    Portrait of Macon C. 'Mike' Ellis, Jr. James Hansen described Mike Ellis as 'the first and only person to be in charge of Langley's Magnetoplasmadynamcis (MPD) Branch.' He was 'an NACA veteran who was 42 years old when the branch was organized. Ellis had come to work at Langley in 1939, and over the course of his career at the laboratory, he had been involved in pioneering work on the aerodynamics of jet engines, ramjets, and supersonic inlets and nozzles. Fittingly, Ellis had worked for Eastman Jacobs and with Arthur Kantrowitz in the early 1940s, and he had heard firsthand accounts of his former colleagues' attempts to design a fusion reactor in the spring of 1938. By the late 1950s, Ellis was one of Langley's most outspoken believers in MPD's promise of technological benefits. Ellis encouraged Floyd Thompson's enthusiasm for MPD and persuaded Langley's senior staff of mostly engineers that MPD was a field of research vital to the future of NASA. When the time came to pick someone to head the new branch, Ellis was unquestionably the person for the job. 'Ellis was no extraordinary 'scientific brain.' As an aeronautical engineer, his talents were quite respectable, but he possessed no special competency in the physics of fluids beyond his experience in aerodynamics or gas dynamics. He was always the first to admit that the complexities of plasma physics and MPD were such that 'there was no way' that he personally could conduct basic MPD research. That challenge he would leave to minds more suited for it. But Ellis could bring the MPD researchers together as a unit, serve as their strong external advocate, shield them from front-office pressures, and make sure that they received the support they needed to carry out their work. 'I just tried to keep my head above water,' Ellis explains, 'and keep these *mad scientists' from going off on too many tangents, or going mad myself.' Published in James R. Hansen, Spaceflight Revolution: NASA Langley Research Center From

  4. Obituary: Ernest Hurst Cherrington, Jr., 1909-1996

    Science.gov (United States)

    Osterbrock, Donald E.

    2003-12-01

    Ernest H. Cherrington, Jr., a long-time member of the AAS, died in San Jose, California on 13 July 1996, following a long illness. He had a short but active career as a research astronomer at Perkins Observatory at Ohio Wesleyan University in Delaware, Ohio before World War II, in which he served as an officer in the Army Air Force. After the war ended he turned to full-time teaching and administration at the University of Akron, and then at Hood College in Frederick, Maryland. Ernest was born on 10 September 1909 in Westerville, Ohio, where his father, Ernest H. Cherrington, Sr., was a leader in the temperance movement and publisher of "American Issue", a Prohibitionist magazine. Ernest Jr.'s mother, Betty Clifford (née Denny) Cherrington, was a homemaker. He was an outstanding student in high school and at Ohio Wesleyan University, which he entered in 1927. The little university's Perkins Observatory with its 69-inch reflector, briefly the second largest telescope in the United States, had just been built and gone into operation. After graduating with a BA magna cum laude in astronomy in 1931, Ernest stayed on one more year and earned his MS with a thesis on the motion of material in the tail of Comet Morehouse, supervised by Nicholas T. Bobrovnikoff. In 1932 Ernest entered the University of California at Berkeley as a graduate student, with a one-year teaching assistantship in the Astronomical Department. This was followed by a two-year Lick Observatory Fellowship. In June 1933 he married Ann McAfee Naylor, who had been a classmate at Delaware High School and Ohio Wesleyan. Ernest did his PhD thesis on spectrophotometry of the Mg I b lines in the solar spectrum, using a high-resolution grating spectrograph on the Berkeley campus, designed by C. Donald Shane, his adviser. In this thesis, Ernest tested and improved the then current theory of strong absorption lines in stellar atmospheres. He also spent several short periods at Lick Observatory on Mount Hamilton

  5. 伪狂犬病毒变异株(JS-2012)对仔猪的致病性研究%PATHOGENICITY OF VARIANT STRAIN JS-2012 OF PSEUDORABIES VIRUS IN PIGLETS

    Institute of Scientific and Technical Information of China (English)

    童武; 周艳君; 童光志; 郑浩; 单同领; 刘飞; 梁超; 李国新; 姜一峰; 于海; 高飞

    2014-01-01

    本实验室2012年从江苏省太仓市某发病猪场分离到1株变异的伪狂犬病毒,命名为JS-2012。为了研究该分离株对仔猪的致病性,将12头15日龄的伪狂犬病毒阴性仔猪随机分为3组,其中2组(每组5头猪)分别通过肌肉注射和滴鼻接种JS-2012毒,第3组2头猪做空白对照。接种病毒的仔猪在攻毒后24 h体温均开始升高,4 d后开始死亡,死亡率为100%。临床观察发现,滴鼻组仔猪发病死亡明显快于肌肉注射组。对病死猪进行剖解,均可见大脑血管扩张并出血等典型的伪狂犬病病理变化。病理切片显示猪的脑蛛网膜下腔严重出血,其他各脏器也均有严重病理变化。结果表明该变异株JS-2012为伪狂犬强毒毒株。%In December 2012, a variant strain JS-2012 of porcine Pseudorabies virus (PRV) was isolated from a diseased piglet in Taicang city Jiangsu Province. To study the pathogenicity of JS-2012, twelve 15-day-old PRV-free piglets were divided into 3 groups:intramuscular injection group (5 piglets), intranasal inoculation group (5 piglets) and non-treatment control group (2 piglets). At 24 h post infection, body temperature of piglets in ten 15-day-old inoculation piglets in two infection groups increased. At day 4 post infection, piglets in both infected group started to die. The intranasal group died faster than those in intramuscular injection group although the mortality of both infection groups was 100%. Dead piglets were necropsied for pathological examination. Vasodilatation and angiorhagia were found in brain, which were typical lesions caused by PRV. Severe subarachnoid hemorrhage and lesions in other organs were also recorded. In conclusion, JS-2012 was a virulent PRV variant.

  6. Exploring Sea Ice Composition Using Semantic Data Dictionaries and qb.js

    Science.gov (United States)

    McCusker, J. P.; Duerr, R. E.; Khalsa, S. S.; Pulsifer, P. L.; Parsons, M. A.; Fox, P. A.; McGuinness, D. L.

    2012-12-01

    Sea Ice is a fundamental component of the Earth system that is undergoing rapid change. Yet sea ice data are described in myriad different, even unique, formats and representations. We show how the Sea Ice Grid (SIGRID) 3 data format and other representations of sea ice concentrations, age, and thickness based on the World Meteorological Organization (WMO) "egg code" can be easily mapped into multidimensional data. The data can then be readily projected onto commonly available geographic mapping tools in a multidimensional analysis environment. Our analysis environment, qb.js, uses Semantic Web standards and Semantic Data Dictionaries, a mixture of multiple ontologies, to provide a data exploration and visualization environment. Geographic and temporal extent are expressed as dimensions of sea ice, while concentrations, age, and thickness as measures of the ice. These dimensions and measures are rendered into a Resource Description Framework (RDF) graph that is described using a Semantic Data Dictionary. This tool will allow users to easily see and understand changes in sea ice extent over many years.

  7. Micro-grid platform based on NODE.JS architecture, implemented in electrical network instrumentation

    Science.gov (United States)

    Duque, M.; Cando, E.; Aguinaga, A.; Llulluna, F.; Jara, N.; Moreno, T.

    2016-05-01

    In this document, I propose a theory about the impact of systems based on microgrids in non-industrialized countries that have the goal to improve energy exploitation through alternatives methods of a clean and renewable energy generation and the creation of the app to manage the behavior of the micro-grids based on the NodeJS, Django and IOJS technologies. The micro-grids allow the optimal way to manage energy flow by electric injection directly in electric network small urban's cells in a low cost and available way. In difference from conventional systems, micro-grids can communicate between them to carry energy to places that have higher demand in accurate moments. This system does not require energy storage, so, costs are lower than conventional systems like fuel cells, solar panels or else; even though micro-grids are independent systems, they are not isolated. The impact that this analysis will generate, is the improvement of the electrical network without having greater control than an intelligent network (SMART-GRID); this leads to move to a 20% increase in energy use in a specified network; that suggest there are others sources of energy generation; but for today's needs, we need to standardize methods and remain in place to support all future technologies and the best option are the Smart Grids and Micro-Grids.

  8. Building HTML5 games with ImpactJS an introduction on HTML5 game development

    CERN Document Server

    Freeman, Jesse

    2012-01-01

    Create a real 2D game from start to finish with ImpactJS, the JavaScript game framework that works with the HTML5's Canvas element. Making video games is hard work that requires technical skills, a lot of planning, and-most critically-a commitment to completing the project. With this hands-on guide, you'll learn how to use Impact with other technologies step-by-step. You'll pick up important tips about game design, and discover how to publish Impact games to the Web, desktop, and mobile-including a method to package your game as a native iOS app. Packed with screen shots and sample code, this book is ideal for game developers of all levels. Set up your development environment and discover Impact's advantagesBuild a complete game with core logic, collision detection, and player and monster behaviorLearn why a game design document is critical before you start buildingDisplay and animate game artwork with sprite sheetsAdd sound effects, background music, and textCreate screens to display stats and in-game statu...

  9. The Nitric Oxide Prodrug JS-K Induces Ca(2+)-Mediated Apoptosis in Human Hepatocellular Carcinoma HepG2 Cells.

    Science.gov (United States)

    Liu, Ling; Wang, Dongmei; Wang, Jiangang; Wang, Shuying

    2016-04-01

    Hepatocellular carcinoma is one of the most common and deadly forms of human malignancies. JS-K, O(2)-(2, 4-dinitrophenyl) 1-[(4-ethoxycarbonyl) piperazin-1-yl] diazen-1-ium-1, 2-diolate, has the ability to induce apoptosis of tumor cell lines. In the present study, JS-K inhibited the proliferation of HepG2 cells in a time- and concentration-dependent manner and significantly induced apoptosis. JS-K enhanced the ratio of Bax-to-Bcl-2, released of cytochrome c (Cyt c) from mitochondria and the activated caspase-9/3. JS-K caused an increasing cytosolic Ca(2+) and the loss of mitochondrial membrane potential. Carboxy-PTIO (a NO scavenger) and BAPTA-AM (an intracellular Ca(2+) chelator) significantly blocked an increasing cytosolic Ca(2+) in JS-K-induced HepG2 cells apoptosis, especially Carboxy-PTIO. Meanwhile, Carboxy-PTIO and BAPTA-AM treatment both attenuate JS-K-induced apoptosis through upregulation of Bcl-2, downregulation of Bax, reduction of Cyt c release from mitochondria to cytoplasm and inactivation of caspase-9/3. In summary, JS-K induced HepG2 cells apoptosis via Ca(2+)/caspase-3-mediated mitochondrial pathway.

  10. Nucleotide sequencing of hepatitis A virus Js-4 strain subcultured in human diploid cells%甲型肝炎病毒Js-4株经人二倍体细胞传代后的核苷酸序列分析

    Institute of Scientific and Technical Information of China (English)

    胡艳灵; 陈统球; 黄明; 戚凤春; 崔燕萍; 潘翔

    2012-01-01

    目的 分析甲型肝炎病毒(Hepatitis A virus,HAV)Js-4株经人二倍体细胞MRC-5传代后的核苷酸序列变异情况.方法 将HAV Js-4株经Vero细胞适应14代获得的原始株Js-4-V14经人二倍体细胞MRC-5于35℃连续适应培养15代,取其中8个适应株(Js-4-M2、Js-4-M3、Js-4-M4、Js-4-M5、Js-4-M10、Js-4-M12、Js-4-M14、Js-4-M15)及原始株,提取病毒基因组RNA,通过RTPCR扩增病毒全基因组,采用生物信息学软件DNAstar Lasergene 7进行序列分析.结果 8个适应株全基因组与Js-4-V14株的核苷酸序列同源性在99.8%~100.0%之间;第5代适应株在5′-NCR(101~ 200 bp)发生较大变异,表现为105~157bp缺失,之后该突变稳定遗传;第10、12、14、15代适应株在2A(3 012 ~3 210 bp)区段3 122位点发生点突变;8个适应株和Js-4-V14毒株与野毒株HM175为同一基因亚型,均为IB型;9个毒株的主要抗原位点与野生株HM175完全一致.结论 HAV Js-4-V14株在MRC-5细胞传代适应过程中,主要抗原位点未发生突变,其与细胞适应性和病毒增殖有关的基因在传代早期已经变异,传代后期这些变异保持相对稳定.%Objective To analyze the variation of nucleotide sequence of hepatitis A virus (HAV) Js-4 strain after subculture in human diploid MRC-5 cells. Methods HAV Js-4 strain was subcultured in Vero cells for 14 passages, and the obtained Js-4-V14 strain was inoculated to MRC-5 cells and further subcultured at 35 Xl for 15 passages. Genomic RNAs were extracted from Js-4-V14 strain as well as eight adapted strains, i. e. Js-4-M2, Js-4-M3, Js-4-M4, Js-4-M5, Js-4-M10, Js-4-Mu, Js-4-M14 and Js-4-Mi5, with which the whole genomes were amplified by RT-PCR and sequenced by bioinformatics software DNAstar Lasergene 1. Results The homologies of whole genomes of eight adapted strains to those of strain Js-4-V14 were 99. 8% ~ 100. 0%. However, obvious variation was observed in 5'-NCR (101 ~ 200 bp) of strain Js-4-M5, expressed as deletion

  11. JS-K, a GST-activated nitric oxide donor prodrug, enhances chemo-sensitivity in renal carcinoma cells and prevents cardiac myocytes toxicity induced by Doxorubicin.

    Science.gov (United States)

    Qiu, Mingning; Ke, Longzhi; Zhang, Sai; Zeng, Xin; Fang, Zesong; Liu, Jianjun

    2017-08-01

    Doxorubicin, a highly effective and widely used anthracycline antibiotic in multiple chemotherapy regimens, has been limited by its cardiotoxicity. The aim of this study is to investigate the effect of nitric oxide donor prodrug JS-K on proliferation and apoptosis in renal carcinoma cells and cardiac myocytes toxicity induced by Doxorubicin and to explore possible p53-related mechanism in renal carcinoma cells. The effect of JS-K on anti-cancer activity of Doxorubicin was investigated in renal carcinoma cells via detecting cell proliferation, cytotoxicity, cell death and apoptosis and expressions of apoptotic-related proteins. Effect of p53 on the combination of JS-K and Doxorubicin was determined using p53 inhibitor Pifithrin-α and p53 activator III. Furthermore, the effect of JS-K on cardiac myocytes toxicity of Doxorubicin was investigated in H9c2 (2-1) cardiac myocytes via measuring cell growth, cell death and apoptosis, expressions of proteins involved in apoptosis and intracellular reactive oxygen species. We demonstrated that JS-K could increase Doxorubicin-induced renal carcinoma cell growth suppression and apoptosis and could increase expressions of proteins that are involved in apoptosis. Additionally, Pifithrin-α reversed the promoting effect of JS-K on Doxorubicin-induced renal carcinoma cell apoptosis; conversely, the p53 activator III exacerbated the promoting effect of JS-K on Doxorubicin-induced renal carcinoma cell apoptosis. Furthermore, JS-K protected H9c2 (2-1) cardiac myocytes against Doxorubicin-induced toxicity and decreased Doxorubicin-induced reactive oxygen species production. JS-K enhances the anti-cancer activity of Doxorubicin in renal carcinoma cells by upregulating p53 expression and prevents cardiac myocytes toxicity of Doxorubicin by decreasing oxidative stress.

  12. Real-time imaging of the growth-inhibitory effect of JS399-19 on Fusarium.

    Science.gov (United States)

    Wollenberg, Rasmus D; Donau, Søren S; Nielsen, Thorbjørn T; Sørensen, Jens L; Giese, Henriette; Wimmer, Reinhard; Søndergaard, Teis E

    2016-11-01

    Real-time imaging was used to study the effects of a novel Fusarium-specific cyanoacrylate fungicide (JS399-19) on growth and morphology of four Fusarium sp. This fungicide targets the motor domain of type I myosin. Fusarium graminearum PH-1, Fusarium solani f. sp. pisi 77-13-4, Fusarium avenaceum IBT8464, and Fusarium avenaceum 05001, which has a K216Q amino-acid substitution at the resistance-implicated site in its myosin type I motor domain, were analyzed. Real-time imaging shows that JS399-19 inhibits fungal growth but not to the extent previously reported. The fungicide causes the hypha to become entangled and unable to extend vertically. This implies that type I myosin in Fusarium is essential for hyphal and mycelia propagation. The K216Q substitution correlates with reduced susceptibility in F. avenaceum. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. Obituary: Benjamin Franklin Peery Jr. (1922-2010)

    Science.gov (United States)

    Cowley, Charles

    2011-12-01

    Professor Benjamin F. Peery, Jr. died at his home in Silver Spring, MD of natural causes on 30 November 2010. His full life began in St. Joseph, MO (home of the Pony Express) on 4 March 1922. His father was a railway mail clerk, so his family moved frequently. Most of his childhood was spent in southeastern Minnesota. He enlisted in the army in 1942, and served in campaigns in North Africa and Italy. After his discharge in 1945, he enrolled in the University of Minnesota, earning a BS in Physics in 1949. One of his early hobbies was to build and fly model airplanes. His intention to pursue aeronautical engineering changed to physics, but after receiving a MS in physics from Fisk University in 1955, he decided on a career in astronomy. He told the editors of the PBS series The Astronomers (1991, in which his career is highlighted) he thought it was shamefully absurd not to know what made the stars shine. So he began PhD studies in astronomy at the University of Michigan (Ann Arbor). His dissertation was on the complex eclipsing binary VV Cephei, where a compact hot star passes behind a cool giant star, revealing the structure of that giant's atmosphere. This task was especially demanding because of the complexity of the system's spectrum and the formidable array of observations assembled by Ben's advisor, Dean McLaughlin. Fortunately, Ben's strong physics background enabled him to design and construct one of the first oscilloscope measuring engines, which his fellow students called the PeeryScope. The final (1961) dissertation is an impressive combination of observational and astrophysical analysis. His degree was obtained in 1962; he had already begun a career at the University of Indiana, where he taught and did research (1959--1976). The Indiana years were highly productive. In addition to his own research, he was advisor on six PhD dissertations, and a master's thesis. Several of his students have also had productive careers. An ADS search on his students' names

  14. Obituary: Richard L. (Dick) Walker, Jr., 1938-2005

    Science.gov (United States)

    Pier, Jeffrey R.; Mason, Brian

    2005-12-01

    Koch Center for Science, Math, and Technology at Deerfield Academy in Massachusetts. He also consulted with James Turrell, providing astronomical position information for the design of the Roden Crater Project outside of Flagstaff. While he will be remembered for his significant scientific contributions to the field of astronomy, those who knew Dick, both scientists and non-scientists alike, will probably remember him best for his humility, his humanity, and his loyal and abiding friendship. He was a man with a terrific sense of humor and an infectious laugh. It was always an honor and pleasure to be in his company. Richard L. Walker, Jr. is survived by his wife, Patricia, two daughters from his first marriage: Brenda Walker of Las Vegas, NV, and Pamela Hepburn of Holland, OH, as well as four children from Patricia's first marriage: Doug Browning of Lake Havasu City, AZ, Michael Browning of Kingman, AZ, Kim Bructo of Orient, OH, and Jennifer Brown of Lake Havasu City, AZ. He is also survived by ten grandchildren and three great-grandchildren. He was preceded in death by his father Richard, mother Mary, and daughter, Paula Jean Elizabeth Stone.

  15. Obituary: Ralph Robert Robbins, Jr., 1938-2005

    Science.gov (United States)

    Hemenway, Mary Kay; Jefferys, William H.; Lambert, David L.

    2007-12-01

    Ralph Robert Robbins, Jr., died on 2 December 2005, in Kyle, Texas. His wife, Maria Elena Robbins, his daughters Julia Robbins Kelso and Stephanie Juarez Balles, his son Matthew Juarez, and five grandchildren survive him. Bob was on the faculty at the University of Texas from 1968 until his retirement in 2003. Bob was born in Wichita, Kansas, on 2 September 1938, the only son of Mildred and Ralph Robert Robbins, Sr. Guided by his high school's policy to provide a practical education to children of working-class parents, Bob began high school with a heavy dose of vocational courses until the results of a test indicated his special talent in mathematics. He was awarded a full scholarship to Yale University, graduating magna cum laude in mathematics in 1960. He won the Warner Prize in Mathematics at Yale that year. He received his Ph.D. in 1966 with a dissertation entitled "The Triplet Spectrum of Neutral Helium in Expanding Nebulae" from the University of California at Berkeley. His interest in college teaching was ignited at this time through summer teaching positions at San Mateo California Junior College and the Ohio State University. Following a year at Texas as a McDonald Observatory Post-doctoral Fellow, Bob taught for a year in the physics department of the University of Houston before returning to the University of Texas at Austin as an Assistant Professor of Astronomy in 1968. He was promoted to Associate Professor in 1972. Bob's research in the early 1970s on theoretical studies of helium was of vital importance to astronomers for over three decades. These pioneering calculations became vital to observational astronomers in the mid-1990s as interest grew in the primordial helium produced by the Big Bang. Bob's interest and influence in education was international in scope. In the summers 1968-1970, he was a government consultant in Mathematics in East Pakistan (now Bangladesh). He consulted with the government that was preparing a master plan for technical

  16. Obituary: George Hamilton Bowen Jr. (1925-2009)

    Science.gov (United States)

    Willson, Lee Anne; Struck, Curtis

    2011-12-01

    Our colleague and collaborator George Hamilton Bowen, Jr., passed away November 1, 2009 in Ames, Iowa. George was born June 20, 1925 in Tulsa, Oklahoma to George and Dorothy (Huntington) Bowen. He married Marjorie Brown June 19, 1948 in Redondo Beach, California; they had five children, with eight grandchildren and five great-grandchildren at the time of his death. George H. Bowen's third or perhaps his fourth career was in astronomy. He was drafted into the navy in 1944, at the end of his first year as a student at Caltech, and ended his war-time service as an electronic technician on the aircraft carrier Shangri-La. He later said "In just nine months, starting from scratch (Ohm's law!), we learned an amazing amount - not by memorization, of course, but by study and real understanding of the basic function of the most advanced AC circuits then being used for instrumentation, measurements, communications, control systems, and much more." He gained a confidence that he could quickly and accurately diagnose and solve technical problems that stood him well in future work. One accomplishment he took particular pride in was figuring out how the radar control used cams and gears to solve the trigonometry for accurate pointing. He also described how the captain was alarmed when weather conditions changed so that refraction no longer showed them distant, small boats around the curvature of Earth. After the war, George Bowen returned to undergraduate and eventually graduate study at Caltech, where he was recruited to the biophysics research group headed by future Nobel Laureate Max Delbrück. George often described his joy in working with these first-rate scientists and finding himself accepted as a part of the effort. He finished his BS with honors in 1949 and his PhD in 1953 with a thesis on "Kinetic Studies on the Mechanism of Photoreactivation of Bacteriophase T2 Inactivated by Ultraviolet Light" involving work with E Coli. This work was supported by grants from the U

  17. SN 2009js AT THE CROSSROADS BETWEEN NORMAL AND SUBLUMINOUS TYPE IIP SUPERNOVAE: OPTICAL AND MID-INFRARED EVOLUTION

    Energy Technology Data Exchange (ETDEWEB)

    Gandhi, P. [Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, 3-1-1 Yoshinodai, chuo-ku, Sagamihara, Kanagawa 252-5210 (Japan); Yamanaka, M.; Itoh, R. [Department of Physical Science, Hiroshima University, Kagamiyama 1-3-1, Higashi-Hiroshima 739-8526 (Japan); Tanaka, M. [National Astronomical Observatory, Mitaka, Tokyo (Japan); Nozawa, T.; Maeda, K.; Moriya, T. J. [Kavli Institute for the Physics and Mathematics of the Universe, University of Tokyo, Kashiwa (Japan); Kawabata, K. S. [Hiroshima Astrophysical Science Center, Hiroshima University, Higashi-Hiroshima, Hiroshima 739-8526 (Japan); Saviane, I. [European Southern Observatory, Alonso de Cordova 3107, Santiago 19 (Chile); Hattori, T. [Subaru Telescope, National Astronomical Observatory of Japan, Hilo, HI 96720 (United States); Sasada, M. [Department of Astronomy, Graduate School of Science, Kyoto University, Kyoto 606-8502 (Japan)

    2013-04-20

    We present a study of SN 2009js in NGC 918. Multi-band Kanata optical photometry covering the first {approx}120 days shows the source to be a Type IIP SN. Reddening is dominated by that due to our Galaxy. One-year-post-explosion photometry with the New Technology Telescope and a Subaru optical spectrum 16 days post-discovery both imply a good match with the well-studied subluminous SN 2005cs. The plateau-phase luminosity of SN 2009js and its plateau duration are more similar to the intermediate luminosity IIP SN 2008in. Thus, SN 2009js shares characteristics with both subluminous and intermediate luminosity supernovae (SNe). Its radioactive tail luminosity lies between SN 2005cs and SN 2008in, whereas its quasi-bolometric luminosity decline from peak to plateau (quantified by a newly defined parameter {Delta}logL, which measures adiabatic cooling following shock breakout) is much smaller than both the others'. We estimate the ejected mass of {sup 56}Ni to be low ({approx}0.007 M{sub Sun }). The SN explosion energy appears to have been small, similar to that of SN 2005cs. SN 2009js is the first subluminous SN IIP to be studied in the mid-infrared. It was serendipitously caught by Spitzer at very early times. In addition, it was detected by WISE 105 days later with a significant 4.6 {mu}m flux excess above the photosphere. The infrared excess luminosity relative to the photosphere is clearly smaller than that of SN 2004dj, which has been extensively studied in the mid-infrared. The excess may be tentatively assigned to heated dust with mass {approx}3 Multiplication-Sign 10{sup -5} M{sub Sun }, or to CO fundamental emission as a precursor to dust formation.

  18. Phosphate-binding protein from Polaromonas JS666: purification, characterization, crystallization and sulfur SAD phasing

    Energy Technology Data Exchange (ETDEWEB)

    Pegos, Vanessa R.; Hey, Louis; LaMirande, Jacob; Pfeffer, Rachel; Lipsh, Rosalie; Amitay, Moshe; Gonzalez, Daniel; Elias, Mikael (JCT-Israel); (UMM); (CNRS-UMR)

    2017-05-25

    Phosphate-binding proteins (PBPs) are key proteins that belong to the bacterial ABC-type phosphate transporters. PBPs are periplasmic (or membrane-anchored) proteins that capture phosphate anions from the environment and release them to the transmembrane transporter. Recent work has suggested that PBPs have evolved for high affinity as well as high selectivity. In particular, a short, unique hydrogen bond between the phosphate anion and an aspartate residue has been shown to be critical for selectivity, yet is not strictly conserved in PBPs. Here, the PBP fromPolaromonasJS666 is focused on. Interestingly, this PBP is predicted to harbor different phosphate-binding residues to currently known PBPs. Here, it is shown that the PBP fromPolaromonasJS666 is capable of binding phosphate, with a maximal binding activity at pH 8. Its structure is expected to reveal its binding-cleft configuration as well as its phosphate-binding mode. Here, the expression, purification, characterization, crystallization and X-ray diffraction data collection to 1.35 Å resolution of the PBP fromPolaromonasJS666 are reported.

  19. node.js izmantošana tīmekļa lapu izstrādē

    OpenAIRE

    Uibo, Andrejs

    2011-01-01

    Šā dokumenta mērķis bija izpētīt jaunu tīmekļa serveru tehnoloģiju - node.js. Node.js 2009 gadā izveidoja Raijans Dāls (Ryan Dahl). Tā ir ieguvusi milzīgu popularitāti dēļ atšķirīgās - asinhronās pieejas tīmekļa serveru izstrādē, ātruma un JavaScript izmantošanu servera pusē. Salīdzinot to ar Apache tīmekļa serveri tika noskaidrots, ka node.js ir daudz priekšrocību, tādu kā ātra, nebloķējoša koda izpilde, asinhrona pieprasījumu apstrāde un spēja apstrādāt lielu skaitu vienlaicīgu pieprasījum...

  20. A Discourse Analysis of the Centered and Critical Scholar-Activism of Martin Luther King Jr.

    OpenAIRE

    Keatts, Quenton

    2010-01-01

    The purpose of this project is to investigate the often neglected research concerning the Reverend Dr. Martin Luther King, Jr. and his scholar-activism. This project is intended to look for evidence of intellectual leadership within Kingâ s writings in an effort to classify King within the Scholar-Activist paradigm in Africana Studies. Further, the aim is to examine Martin Luther King, Jr. from the critical and centered Scholar-Activist paradigm of Africana Studies based on an analysis of ...

  1. Has the Dream Been Fulfilled? Dr. Martin Luther King, Jr. & President Barack Hussein Obama

    Science.gov (United States)

    Robinson, Nichelle Boyd; Moore, Virginia J.; Williams-Black, Thea H.

    2015-01-01

    Equality for all was the dream of Dr. Martin Luther King, Jr. and he knowingly laid the foundation for and inspired the first African-American President of the United States of America, Barack Hussein Obama, who also had the dream of "Change" for America. These men exhibited how working together can make dreams become reality. For the…

  2. Ability of Lactobacillus plantarum JR64 isolated from noni juice in lowering Cholesterol in vivo

    Directory of Open Access Journals (Sweden)

    Lanjar Sumarno

    2011-07-01

    Full Text Available Recently public’s attention to the importance of healthy food increases rapidly. Probiotic based food exploiting lactic acid bacteria is among the healthy food. Lactobacillus plantarum JR64 isolate from Morinda citrifolia fruit was assessed for its probiotic in-vivo by using Wistar  Rat. The purpose of this research was to study the ability of probiotic Lactobacillus plantarum JR64 in lowering serum LDL (Low Density Lipoprotein of Wistar Rat. Twenty Rats were grouped into 4, each group consisted of 5 Rats. First Group was a negative control  given standard normal diet of 20 gr/day plus aquadest. Second Grup was a positive control given cholesterol normal diet 20 gr /day plus Propil Tio Urasil (PTU 60 mg/kg body weight/day. Third Group was supplemented with normal diet 20 gr /day plus Propil Tio Urasil (PTU 60 mg  kg body weight /day and  1012 CFU Lactobacillus plantarum JR64. Fourth Group was the same as third Group unless the probiotic using commercial probiotic Lactobacillus bulgariccus at 1012 CFU. Blood samples were withdrawn for measurement of total cholesterol, triglyceride, High Density Lipoprotein (HDL, and Low Density Lipoprotein (LDL cholesterol every week and measured by using spectrophotometer with 546 nanometers wavelength. The results show that probiotic Lactobacillus plantarum JR64 isolated from noni juice significantly (p < 0,01 reduce Low Density Lipoprotein (LDL and Triglyceride in vivo  and tend to reduce High Density Lipoprotein (HDL and total cholesterol.

  3. Commemoration of Dr. Martin Luther King, Jr., January 15, 1929-April 4, 1968. Revised.

    Science.gov (United States)

    Montgomery County Public Schools, Rockville, MD.

    Developed in honor of Dr. Martin Luther King, Jr., this is a short collection of suggested activities to teach black awareness in the elementary and secondary grades through King's philosophy. An introductory biographical sketch of King and an article about his accomplishments are provided. Activities are divided into grade-level ranges for the…

  4. Fighting Fair. Dr. Martin Luther King, Jr. for Kids. Second Edition.

    Science.gov (United States)

    Schmidt, Fran; Friedman, Alice

    This curriculum guide for grades 4 through 9 uses the life and work of Dr. Martin Luther King, Jr., to teach conflict resolution and to explore the philosophy of non-violence for daily life. To enable students to learn and apply non-violence, it must be modeled in a classroom environment that builds trust and a sense of community. Each of the…

  5. Abuse of Power? : J. Edgar Hoover vs. Robert Kennedy and Martin Luther King, Jr.

    OpenAIRE

    Isaksen, Vigdis

    2002-01-01

    In this thesis I have looked at how J. Edgar Hoover came to power as Director of the FBI, and how he later used that power against Attorney General Robert Kennedy and SCLC leader Martin Luther King, Jr. I have further analyzed the reasons and motives for Hoover's actions by, among other things, making a psychological profile on the Director.

  6. Sharing the Gift of Jazz: An Interview with Willie L. Hill Jr.

    Science.gov (United States)

    Howe, Brad

    2011-01-01

    This article presents an interview with Willie L. Hill Jr., founder and director of the Society for Jazz Education. Currently a professor of music education at the University of Massachusetts-Amherst and the director of the UMass Fine Arts Center, Hill has served as director of education for the Thelonious Monk Institute of Jazz. He is a past…

  7. Addressing Curriculum Deficiencies on Martin Luther King, Jr. through Computer Assisted Instruction and Multimedia Resources.

    Science.gov (United States)

    Kim, James S.

    Students need to see past heroes as real people who struggled with ordinary problems in order to see the relevancy of studying history and to act practically upon the lessons that each leader teaches them. This study attempts to answer two questions relating to Martin Luther King, Jr.: (1) What do we teach our children about King? and (2) Can we…

  8. Steam System Efficiency Optimized After J.R. Simplot Fertilizer Plant Receives Energy Assessment

    Energy Technology Data Exchange (ETDEWEB)

    None

    2008-07-01

    The J.R. Simplot Company's Don Plant in Pocatello, Idaho, optimized boiler operation, improved condensate recovery, and fixed steam traps and leaks for a simple payback of 6.5 months. Results are being shared with other Simplot facilities and other recommendations identified during the assessment are under consideration.

  9. Steam System Efficiency Optimized After J.R. Simplot Fertilizer Plant Receives Energy Assessment

    Energy Technology Data Exchange (ETDEWEB)

    2008-07-01

    This case study describes how the J.R. Simplot company's Don Plant in Pocatello, Idaho, achieved annual savings of $335,000 and 75,000 MMBtu, with a simple payback of 6.5 months, after receiving a DOE Save Energy Now energy assessment.

  10. "Qualitative Liberalism": Arthur Schlesinger, Jr. and the Persuasive Uses of Definition and History.

    Science.gov (United States)

    Depoe, Stephen P.

    1989-01-01

    Applies the concepts of persuasive definition, ideograph, and ideological history in an analysis of Arthur Schlesinger, Jr.'s, discourse. Uses this analysis to enhance understanding of how the strategic definition of terms such as "liberal" can influence the ongoing struggle to set presumptions in American political life. (SR)

  11. Abuse of Power? : J. Edgar Hoover vs. Robert Kennedy and Martin Luther King, Jr.

    OpenAIRE

    Isaksen, Vigdis

    2002-01-01

    In this thesis I have looked at how J. Edgar Hoover came to power as Director of the FBI, and how he later used that power against Attorney General Robert Kennedy and SCLC leader Martin Luther King, Jr. I have further analyzed the reasons and motives for Hoover's actions by, among other things, making a psychological profile on the Director.

  12. Mounting a Curricular Revolution: An Interview with Henry Louis Gates, Jr.

    Science.gov (United States)

    von Zastrow, Claus

    2009-01-01

    This article presents an interview with Henry Louis Gates, Jr., Harvard professor and cultural critic who has captured 25 million viewers with his PBS documentary series, African American Lives (WNET). Using genealogical research and DNA science, Gates traces the family history of 19 famous African Americans. What results is a rich and moving…

  13. Sharing the Gift of Jazz: An Interview with Willie L. Hill Jr.

    Science.gov (United States)

    Howe, Brad

    2011-01-01

    This article presents an interview with Willie L. Hill Jr., founder and director of the Society for Jazz Education. Currently a professor of music education at the University of Massachusetts-Amherst and the director of the UMass Fine Arts Center, Hill has served as director of education for the Thelonious Monk Institute of Jazz. He is a past…

  14. Has the Dream Been Fulfilled? Dr. Martin Luther King, Jr. & President Barack Hussein Obama

    Science.gov (United States)

    Robinson, Nichelle Boyd; Moore, Virginia J.; Williams-Black, Thea H.

    2015-01-01

    Equality for all was the dream of Dr. Martin Luther King, Jr. and he knowingly laid the foundation for and inspired the first African-American President of the United States of America, Barack Hussein Obama, who also had the dream of "Change" for America. These men exhibited how working together can make dreams become reality. For the…

  15. Martin Luther King, Jr.: A Lesson with Interdisciplinary Connections for Middle-Level Music Students.

    Science.gov (United States)

    Early, Mary Frances; Terry, Cynthia

    This lesson begins with a very brief biography of Martin Luther King, Jr. The lesson identifies its educational objectives; addresses National Standards for Music Education; lists materials needed; details six step-by-step classroom procedures for lesson implementation; and provides curriculum connections for language arts, visual art, physical…

  16. Martin Luther King, Jr. and the Power of Nonviolence. [Lesson Plan].

    Science.gov (United States)

    National Endowment for the Humanities (NFAH), Washington, DC.

    This lesson plan introduces students in grades 6-8 to Martin Luther King Jr.'s philosophy of nonviolence and the teachings of Mohandas K. Gandhi that influenced King's views. After considering the political impact of this philosophy, students explore its relevance to personal life. In these 6 lessons students will: (1) examine the philosophy of…

  17. Let Freedom Ring: The Life & Legacy of Martin Luther King, Jr. [Lesson Plan].

    Science.gov (United States)

    National Endowment for the Humanities (NFAH), Washington, DC.

    This lesson plan teaches students about the life and work of Martin Luther King, Jr. Students listen to a brief biography, view photographs of the March on Washington, and read a portion of King's "I Have a Dream" speech. After studying Dr. King's use of imagery and allusion, students create original poetic phrases about freedom and…

  18. Draft Genome Sequences of Legionella pneumophila JR32 and Lp01 Laboratory Strains Domesticated in Japan

    Science.gov (United States)

    Maita, Chinatsu; Matushita, Mizue; Okubo, Torahiko; Matsuo, Junji; Miyake, Masaki; Nagai, Hiroki

    2016-01-01

    We report here the draft genome sequences of two Legionella pneumophila variant strains (JR32 and Lp01_666) originally derived from a Philadelphia-1 clinical isolate, domesticated in Japan, with distinct susceptibility to amoebae. Detailed genomic analysis will allow us to better understand Legionella adaptation and survival mechanisms in host cells. PMID:27491976

  19. Henry David Thoreau, Martin Luther King Jr., and the American Tradition of Protest.

    Science.gov (United States)

    Powell, Brent

    1995-01-01

    Maintains that Henry David Thoreau and Martin Luther King, Jr. fundamentally altered the tradition of protest and reform. Compares and contrasts the role of each man in U.S. social and constitutional history. Concludes that while Thoreau lacked the broad influence of King, his writings influenced both King and Mohandas Gandhi. (CFR)

  20. The Rhetorical Construction of Time in Martin Luther King, Jr.'s "Letter from Birmingham Jail."

    Science.gov (United States)

    Lee, Ronald E.

    1991-01-01

    Explores the rhetorical use of time in Martin Luther King, Jr.'s "Letter from Birmingham Jail." Offers an explanation of the ideological heritage that temporarily unifies the discourse. Describes the letter's recent, historical, and spiritual time frames, accounts for the ideological purpose each serves, and explains on what ground they…

  1. Martin Luther King, Jr. Borrows a Revolution: Argument, Audience, and Implications of a Secondhand Universe.

    Science.gov (United States)

    Miller, Keith D.

    1986-01-01

    Examines features of and sources for the discourse of Martin Luther King, Jr., as they relate to the language and assumptions favored by his listeners and readers in an effort to understand how speakers and writers can successfully argue from premises that audiences accept. Indicates how an understanding of King can help in composition…

  2. The Fierce Urgency of now: Honoring Martin Luther King, Jr. in and out of the Classroom.

    Science.gov (United States)

    Kazemek, Francis E.

    1988-01-01

    Explores how educators and their students can best honor Martin Luther King, Jr.'s, memory by using his life and works as a catalyst for acting upon school and society in a way that fosters social change. (Author/BJV)

  3. Children's Books on Martin Luther King, Jr. Offer a One-Dimensional View.

    Science.gov (United States)

    Banfield, Beryle

    1985-01-01

    Reviews children's books, teacher references, mini-plays, and curriculum resources that relate to the life of Martin Luther King, Jr. Reports that most of these sources ignore growth and changes within King's life and thought, the role models who shaped his philosophy, or his participation in issues such as the Vietnam War and poverty. (KH)

  4. 78 FR 10172 - Lisa Anne Cornell and G. Ware Cornell, Jr. v. Princess Cruise Lines, Ltd. (Corp), Carnival PLC...

    Science.gov (United States)

    2013-02-13

    ... Lisa Anne Cornell and G. Ware Cornell, Jr. v. Princess Cruise Lines, Ltd. (Corp), Carnival PLC, and..., Jr., hereinafter ``Complainants,'' against Princess Cruise Lines, Ltd (Corp), Carnival plc, and... common carrier for hire of passengers from ports in the United States;'' Respondent Carnival plc ``is...

  5. J.R. SIMPLOT EX-SITU BIOREMEDIATION TECHNOLOGY FOR TREATMENT OF TNT-CONTAMINATED SOILS - INNOVATIVE TECHNOLOGY EVALUATION REPORT

    Science.gov (United States)

    This report summarizes the findings of the second evaluation of the J.R. Simplot Ex-situ Bioremediation Technology also known as the Simplot Anaerobic Bioremediation (SABRE™) process. This technology was developed by the J.R. Simplot Company to biologically degrade nitroaromatic...

  6. J.R. SIMPLOT EX-SITU BIOREMEDIATION TECHNOLOGY FOR TREATMENT OF DINOSEB-CONTAMINATED SOILS - INNOVATIVE TECHNOLOGY REPORT

    Science.gov (United States)

    This report summarizes the findings of an evaluation of the J.R. Simplot Ex-Situ Bioremediation Technology on the degradation of dinoseb (2-set-butyl-4,6-dinitrophenol) an agricultural herbicide. This technology was developed by the J.R. Simplot Company (Simplot) to biologically ...

  7. Mattoso Câmara Jr. e a palavra prosódica Mattoso Câmara Jr. and the prosodic word

    Directory of Open Access Journals (Sweden)

    Leda Bisol

    2004-01-01

    Full Text Available Este artigo que se detém no conceito de palavra fonológica, fundamentando-se na Teoria Prosódica (Booij 1983, (Nespor & Vogel 1986, relembra Mattoso Câmara Jr., o primeiro entre nós a fazer específica diferença entre dois tipos de palavra, a que diz respeito aos morfemas, a que diz respeito à presença de um acento. Discutem-se a interação entre as duas unidades, a dimensão e as funções da palavra fonológica. Nestas simples linhas, nossa homenagem ao grande mestre de quem tivemos a felicidade de ser aluna.The subject of this paper is the phonological word and its interaction with the morphological word. The dimension, the domain and the functions of the phonological word are discussed following the principles of Prosodic Theory (Booij 1983, (Nespor & Vogel 1986. Câmara Jr's statements regarding Brazilian Portuguese are the basis of the considerations.

  8. Biodegradation of 2,4-dinitroanisole (DNAN) by Nocardioides sp. JS1661 in water, soil and bioreactors.

    Science.gov (United States)

    Karthikeyan, Smruthi; Spain, Jim C

    2016-07-15

    2,4-Dinitroanisole (DNAN), a low sensitivity replacement for TNT, is a key component of a new class of melt cast formulations designed for use in insensitive munitions. It is therefore essential that its fate and transport in the environment be assessed before its large scale implementation. Several recent studies have described reductive biotransformation pathways leading to dead-end products. Recently a Nocardioides strain, JS1661 was isolated based on its ability to mineralize DNAN via the 2,4-dinitrophenol (DNP) pathway. However, its potential for degrading DNAN under environmentally relevant conditions was not examined. Therefore we evaluated the aerobic biodegradation of DNAN by JS1661 in non-sterile soil, aqueous media and in a fluidized bed bioreactor over a wide range of DNAN concentrations. DNAN was completely degraded under all tested conditions with little or no accumulation of DNP and almost stoichiometric release of nitrite. Furthermore, when DNAN was used as the sole carbon and nitrogen source, the accumulation of nitrite was dramatically reduced. The results of the study revealed the robustness of the strain over a range of loading rates in various physical environments suggesting that it could provide the basis for waste treatment, bioremediation and bioaugmentation applications.

  9. Bioactive secondary metabolites produced by an endophytic fungus Gaeumannomyces sp. JS0464 from a maritime halophyte Phragmites communis.

    Science.gov (United States)

    Lee, Changyeol; Kim, Soonok; Li, Wei; Bang, Sunghee; Lee, Hanna; Lee, Hyun-Jung; Noh, Eun-Young; Park, Jung-Eun; Bang, Woo Young; Shim, Sang Hee

    2017-03-29

    Endophytes, important plant-associated mycobionts, have attracted a great deal of attention because of their bioactive secondary metabolites. Even though halophytes have been reported to overcome salt stress via associations with their endophytes, few studies have investigated the metabolites produced by the endophytes from halophytes. In this study, a dark septate endophytic fungal strain (JS0464), identified as Gaeumannomyces sp. by ITS sequencing, was isolated from the rhizome of a halophyte, Phragmites communis, in Suncheon bay, South Korea. This strain was cultured on a large scale and extracted with ethyl acetate. Chemical investigations of extracts of JS0464 led to the isolation of two glycosylated dialkylresorcinol derivatives (1-2), an anthraquinone derivative (3) and eight known compounds (4-11), which were identified by spectroscopic analyses incorporating one-dimensional/2D NMR and MS. Nine compounds showed significant nitric oxide reduction activity in lipopolysaccharide-stimulated microglia BV-2 cells, seven of which did not impair cell viability. The results suggest that endophytes from the halophytes could be potential resources for bioactive natural products.The Journal of Antibiotics advance online publication, 29 March 2017; doi:10.1038/ja.2017.39.

  10. Characteristics of phenol degradation in saline conditions of a halophilic strain JS3 isolated from industrial activated sludge.

    Science.gov (United States)

    Jiang, Yu; Yang, Kai; Wang, Hongyu; Shang, Yu; Yang, Xiaojun

    2015-10-15

    Several halophilic bacteria have been reported to degrade phenol. However, there are a few works about salt-tolerant fungi which can utilize phenol as sole source of carbon. In this study, a halophilic strain JS3 which could degrade phenol with high efficiency was separated and identified. The effect of initial phenol concentration on phenol biodegradation was investigated and optimal pH, temperature, as well as salt-tolerance were evaluated. The isolate could degrade less than 800 mg/L phenol completely in 72 h. It grew well when pH, temperature, and salinity were at values of 4.0-9.0, 30-40°C, and 0-7%, respectively. The optimal pH, temperature and salinity were 6.0, 35°C and 0%. More than 99% of 500 mg/L phenol was degraded in the optimal condition within 24h. The tolerance of wide range of pH, temperature and salinity indicated that strain JS3 was effective for phenol removal in hypersaline wastewaters.

  11. Solution strengthened ferritic ductile iron ISO 1083/JS/500-10 provides superior consistent properties in hydraulic rotators

    Institute of Scientific and Technical Information of China (English)

    Dr.Richard Larker

    2009-01-01

    Consistent mechanical and machining properties are essential in many applications where ductile irons offer the most cost-effective way to produce structural parts. In the production of hydraulic rotators, dimensional tolerances are typically 20 μm to obtain designated performance.For castings where intermediate strength and ductility is required, it is common knowledge that conventional ferritic-pearlitic ductile irons such as ISO 1083/500-7 show large hardness variations. These are mainly caused by the notoriously varying pearlite content, both at different locations within a part and between parts in the same or different batches. Cooling rate variations due to different wall thickness and position in the molding box, as well as varying amounts of pearlite-stabilizing elements, all contribute to detrimental hardness variations.The obvious remedy is to avoid pearlite formation, and instead obtain the necessary mechanical properties by solution strengthening of the ferritic matrix by increasing silicon content to 3.7wt% -3.8wt%. The Swedish development in this field 1998 resulted in a national standardization as SS 140725, followed in 2004 by ISO 1083/ JS/500-10.Indexator AB decided 2005 to specify JS/500-10 for all new ductile iron parts and to convert all existing parts. Improvements include reduction by 75% in hardness variations and increase by 30% in cutting tool life, combined with consistently better mechanical properties.

  12. Versión corta de la adaptación española para adolescentes del NEO-PI-R (JS NEO-S

    Directory of Open Access Journals (Sweden)

    Generós Ortet

    2010-01-01

    Full Text Available Este artículo instrumental presenta los primeros datos sobre el desarrollo de la versión corta de la adaptación española para adolescentes, entre 12 y 18 años, del NEO-PI-R (JS NEO-S. Este cuestionario de 150 ítems evalúa las cinco dimensiones y las treinta facetas del Modelo de los Cinco Factores. Las propiedades psicométricas del JS NEO-S fueron investigadas en una muestra de 2.546 adolescentes. Los resultados replicaron la estructura factorial de la versión extensa (JS NEO. Las fiabilidades de consistencia interna y estabilidad temporal de las escalas, en intervalos de un mes y un año, fueron adecuadas. Además, la correlación entre las escalas de la versión corta para adolescentes y la versión para adultos, NEO-PI-R, indicaban un alto grado de equivalencia entre las dos formas. Asimismo, se estudió la asociación del JS NEO con el BFQ-NA que evalúa los cinco factores a nivel de las dimensiones, ya que no tiene subescalas para las facetas. Las correlaciones entre estos cuestionarios aportaron más evidencia sobre la validez de constructo de JS NEO-S.

  13. William Pepper Jr, MD (1843-1898): portrait of a nineteenth-century medical educator.

    Science.gov (United States)

    Lo Re, Vincent; Bellini, Lisa M

    2006-08-01

    Dr William Pepper Jr was a prominent Philadelphia physician whose contributions to medicine in the late 19th century are not widely known. As a young physician he rose in stature rapidly due to his abilities as a diagnostician, teacher, writer and researcher. His primary interest, however, was to improve the education of physicians. He orchestrated the creation of America's first university-controlled teaching hospital, the Hospital of the University of Pennsylvania, enabling substantial improvements in clinical training. Pepper later became Provost of the University of Pennsylvania and ambitiously transformed the curriculum of the medical school, providing greater basic science and clinical training. He also worked to establish several institutes and museums in Philadelphia in order to promote academic pursuits, particularly in medicine. William Pepper Jr was one of the 19th century's foremost medical educators and his accomplishments helped reshape the way medicine was taught throughout the United States.

  14. An Analysis of the Tvergaard Parameters at Low Initial Stress Triaxiality for S235JR Steel

    Directory of Open Access Journals (Sweden)

    G. Kossakowski Paweł

    2015-01-01

    Full Text Available This paper discusses the influence of the Tvergaard parameters, qi, which are basic constants of the Gurson-Tvergaard-Needleman (GTN material model, on the numerically simulated load-carrying capacity of tensile elements made of S235JR steel. The elements were considered to be under static tension at low initial stress triaxiality σm/σe = 1/3. Two sets of the Tvergaard parameters qi were analyzed: those typical of structural steels and those dependent on material strength properties. The results showed that the Tvergaard parameters, qi, had influence on the load-carrying capacity of tensile elements at low initial stress triaxiality. They affected the strength curves and the changes in the void volume fractions determined for S235JR steel elements

  15. Left to right, astronauts John H. Casper, mission commander, and Curtis L. Brown, Jr., pilot, get

    Science.gov (United States)

    1996-01-01

    STS-77 TRAINING VIEW --- Left to right, astronauts John H. Casper, mission commander, and Curtis L. Brown, Jr., pilot, get help with the final touches of suit donning during emergency bailout training for STS-77 crew members in the Johnson Space Centers (JSC) Weightless Environment Training Facility (WET-F). Casper and Brown will join four other astronauts for nine days aboard the Space Shuttle Endeavour next month.

  16. 最后消息:Bodies of JFK Jr.,Wife,Sister-in-Law Found

    Institute of Scientific and Technical Information of China (English)

    Tony; Munroe

    1999-01-01

    Searchers have found the bodies of John F. Kennedy Jr., his wife CarolynBessette Kennedy and her sister Lauren as well as a large piece of their crashedplane off the coast of Martha’s Vineyard, officials said Wednesday. Massachusetts Sen. Edward Kennedy and his two sons headed for the crashsite on a U. S. Coast Guard vessel after the bodies and wreckage (残骸) were

  17. Cicero's de legibus and Martin Luther King, Jr.’s Stride toward freedom

    Directory of Open Access Journals (Sweden)

    Boleslav s. Povšič

    1979-12-01

    Full Text Available He who reads carefully Cicero'sDe Legibus and Martin Luther King, Jr.'s Stride Toward Freedom is surprised to find, mutatis mutandis, on how many points these two great men agree. The historical circumstances are different, but the essential ideas are very similar. The purpose of this paper is to show on what precisely they agree and on what they differ.

  18. Community control of health services. Dr. Martin Luther King, Jr. Health Center's community management system.

    Science.gov (United States)

    Tichy, N M; Taylor, J I

    1976-01-01

    This article presents the case of Dr. Martin Luther King Jr. Health Center's unique community management system in which neighborhood workers have been developed to assume managerial responsibilities and are directing the Center. The Martin Luther King Center experience is instructive because the Center was able to achieve significant community control by focusing primarily on the internal dimension of control, namely, management, without experiencing destructive conflicts and the deterioration of health services.

  19. Jules Verne Voyager, Jr: An Interactive Map Tool for Teaching Plate Tectonics

    Science.gov (United States)

    Hamburger, M. W.; Meertens, C. M.

    2010-12-01

    We present an interactive, web-based map utility that can make new geological and geophysical results accessible to a large number and variety of users. The tool provides a user-friendly interface that allows users to access a variety of maps, satellite images, and geophysical data at a range of spatial scales. The map tool, dubbed 'Jules Verne Voyager, Jr.', allows users to interactively create maps of a variety of study areas around the world. The utility was developed in collaboration with the UNAVCO Consortium for study of global-scale tectonic processes. Users can choose from a variety of base maps (including "Face of the Earth" and "Earth at Night" satellite imagery mosaics, global topography, geoid, sea-floor age, strain rate and seismic hazard maps, and others), add a number of geographic and geophysical overlays (coastlines, political boundaries, rivers and lakes, earthquake and volcano locations, stress axes, etc.), and then superimpose both observed and model velocity vectors representing a compilation of 2933 GPS geodetic measurements from around the world. A remarkable characteristic of the geodetic compilation is that users can select from some 21 plates' frames of reference, allowing a visual representation of both 'absolute' plate motion (in a no-net rotation reference frame) and relative motion along all of the world's plate boundaries. The tool allows users to zoom among at least three map scales. The map tool can be viewed at http://jules.unavco.org/VoyagerJr/Earth. A more detailed version of the map utility, developed in conjunction with the EarthScope initiative, focuses on North America geodynamics, and provides more detailed geophysical and geographic information for the United States, Canada, and Mexico. The ‘EarthScope Voyager’ can be accessed at http://jules.unavco.org/VoyagerJr/EarthScope. Because the system uses pre-constructed gif images and overlays, the system can rapidly create and display maps to a large number of users

  20. Physiology and phylogeny of the candidate phylum "Atribacteria" (formerly OP9/JS1) inferred from single-cell genomics and metagenomics

    Science.gov (United States)

    Dodsworth, J. A.; Murugapiran, S.; Blainey, P. C.; Nobu, M.; Rinke, C.; Schwientek, P.; Gies, E.; Webster, G.; Kille, P.; Weightman, A.; Liu, W. T.; Hallam, S.; Tsiamis, G.; Swingley, W.; Ross, C.; Tringe, S. G.; Chain, P. S.; Scholz, M. B.; Lo, C. C.; Raymond, J.; Quake, S. R.; Woyke, T.; Hedlund, B. P.

    2014-12-01

    Single-cell sequencing and metagenomics have extended the genomics revolution to yet-uncultivated microorganisms and provided insights into the coding potential of this so-called "microbial dark matter", including microbes belonging candidate phyla with no cultivated representatives. As more datasets emerge, comparison of individual genomes from different lineages and habitats can provide insight into the phylogeny, conserved features, and potential metabolic diversity of candidate phyla. The candidate bacterial phylum OP9 was originally found in Obsidian Pool, Yellowstone National Park, and it has since been detected in geothermal springs, petroleum reservoirs, and engineered thermal environments worldwide. JS1, another uncultivated bacterial lineage affiliated with OP9, is often abundant in marine sediments associated with methane hydrates, hydrocarbon seeps, and on continental margins and shelves, and is found in other non-thermal marine and subsurface environments. The phylogenetic relationship between OP9, JS1, and other Bacteria has not been fully resolved, and to date no axenic cultures from these lineages have been reported. Recently, 31 single amplified genomes (SAGs) from six distinct OP9 and JS1 lineages have been obtained using flow cytometric and microfluidic techniques. These SAGs were used to inform metagenome binning techniques that identified OP9/JS1 sequences in several metagenomes, extending genomic coverage in three of the OP9 and JS1 lineages. Phylogenomic analyses of these SAG and metagenome bin datasets suggest that OP9 and JS1 constitute a single, deeply branching phylum, for which the name "Atribacteria" has recently been proposed. Overall, members of the "Atribacteria" are predicted to be heterotrophic anaerobes without the capacity for respiration, with some lineages potentially specializing in secondary fermentation of organic acids. A set of signature "Atribacteria" genes was tentatively identified, including components of a bacterial

  1. J.R. Simplot: Burner Upgrade Project Improves Performance and Saves Energy at a Large Food Processing Plant

    Energy Technology Data Exchange (ETDEWEB)

    2005-09-01

    This DOE Industrial Program case study describes how the J.R. Simplot Company saved energy and money by increasing the efficiency of the steam system in its potato processing plant in Caldwell, Idaho.

  2. J.R. Simplot: Burner Upgrade Project Improves Performance and Saves Energy at a Large Food Processing Plant (Steam)

    Energy Technology Data Exchange (ETDEWEB)

    None

    2005-09-01

    This DOE Industrial Program case study describes how the J.R. Simplot Company saved energy and money by increasing the efficiency of the steam system in its potato processing plant in Caldwell, Idaho.

  3. J.R. Simplot: Burner Upgrade Project Improves Performance and Saves Energy at a Large Food Processing Plant

    Energy Technology Data Exchange (ETDEWEB)

    2005-09-01

    This DOE Industrial Program case study describes how the J.R. Simplot Company saved energy and money by increasing the efficiency of the steam system in its potato processing plant in Caldwell, Idaho.

  4. J.R. Simplot: Burner Upgrade Project Improves Performance and Saves Energy at a Large Food Processing Plant (Steam)

    Energy Technology Data Exchange (ETDEWEB)

    None

    2005-09-01

    This DOE Industrial Program case study describes how the J.R. Simplot Company saved energy and money by increasing the efficiency of the steam system in its potato processing plant in Caldwell, Idaho.

  5. JS-K, a nitric oxide prodrug, induces DNA damage and apoptosis in HBV-positive hepatocellular carcinoma HepG2.2.15 cell.

    Science.gov (United States)

    Liu, Zhengyun; Li, Guangmin; Gou, Ying; Xiao, Dongyan; Luo, Guo; Saavedra, Joseph E; Liu, Jie; Wang, Huan

    2017-08-01

    Hepatocellular carcinoma (HCC) is the most important cause of cancer-related death, and 85% of HCC is caused by chronic HBV infection, the prognosis of patients and the reduction of HBV DNA levels remain unsatisfactory. JS-K, a nitric oxide-releasing diazeniumdiolates, is effective against various tumors, but little is known on its effects on HBV positive HCC. We found that JS-K reduced the expression of HBsAg and HBeAg in HBV-positive HepG2.2.15 cells. This study aimed to further examine anti-tumor effects of JS-K on HepG2.2.15 cells. The MTT assay and colony forming assay were used to study the cell growth inhibition of JS-K; scratch assay and transwell assay were performed to detect cell migration. The cell cycle was detected by flow cytometry. The immunofluorescence, flow cytometry analysis, and western blot were used to study DNA damage and cell apoptosis. JS-K inhibited HepG2.2.15 cell growth in a dose-dependent manner, suppressed cell colony formation and migration, arrested cells gather in the G2 phase. JS-K (1-20μM) increased the expression of DNA damage-associated protein phosphorylation H2AX (γH2AX), phosphorylation of checkpoint kinase 1 (p-Chk1), phosphorylation of checkpoint kinase 2 (p-Chk2), ataxia-telangiectasia mutated (ATM), phosphorylation of ataxia-telangiectasia mutated rad3-related (p-ATR) and apoptotic-associated proteins cleaved caspase-3, cleaved caspase-7, cleaved poly ADP-ribose polymerase (cleaved PARP). The study demonstrated JS-K is effective against HBV-positive HepG2.2.15 cells, the mechanisms are not only related to inhibition of HBsAg and HBeAg secretion, but also related with induction of DNA damage and apoptosis. JS-K is a promising anti-cancer candidate against HBV-positive HCC. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  6. biojs-io-biom, a BioJS component for handling data in Biological Observation Matrix (BIOM) format

    Science.gov (United States)

    Ankenbrand, Markus J.; Terhoeven, Niklas; Hohlfeld, Sonja; Förster, Frank; Keller, Alexander

    2017-01-01

    The Biological Observation Matrix (BIOM) format is widely used to store data from high-throughput studies. It aims at increasing interoperability of bioinformatic tools that process this data. However, due to multiple versions and implementation details, working with this format can be tricky. Currently, libraries in Python, R and Perl are available, whilst such for JavaScript are lacking. Here, we present a BioJS component for parsing BIOM data in all format versions. It supports import, modification, and export via a unified interface. This module aims to facilitate the development of web applications that use BIOM data. Finally, we demonstrate its usefulness by two applications that already use this component. Availability: https://github.com/molbiodiv/biojs-io-biom, https://dx.doi.org/10.5281/zenodo.218277 PMID:28105307

  7. biojs-io-biom, a BioJS component for handling data in Biological Observation Matrix (BIOM) format.

    Science.gov (United States)

    Ankenbrand, Markus J; Terhoeven, Niklas; Hohlfeld, Sonja; Förster, Frank; Keller, Alexander

    2016-01-01

    The Biological Observation Matrix (BIOM) format is widely used to store data from high-throughput studies. It aims at increasing interoperability of bioinformatic tools that process this data. However, due to multiple versions and implementation details, working with this format can be tricky. Currently, libraries in Python, R and Perl are available, whilst such for JavaScript are lacking. Here, we present a BioJS component for parsing BIOM data in all format versions. It supports import, modification, and export via a unified interface. This module aims to facilitate the development of web applications that use BIOM data. Finally, we demonstrate its usefulness by two applications that already use this component. Availability: https://github.com/molbiodiv/biojs-io-biom, https://dx.doi.org/10.5281/zenodo.218277.

  8. Optimization of process parameters for cellulase production from Bacillus sp. JS14 in solid substrate fermentation using response surface methodology

    Directory of Open Access Journals (Sweden)

    Jagdish Singh

    2012-08-01

    Full Text Available The aim of this work was to isolate the potent bacterial strains for the production of cellulose enzyme. A total 30 bacterial isolates showed positive results for the cellulase production but highest enzyme activity was shown by isolate JS 14. From the morphological and biochemical reactions, the isolate was identified as Bacillus sp. Cellulase production was studied by this strain using response surface methodology (RSM. A central composite design (CCD quadratic response surface was applied to explicate the parameters that significantly affected cellulase production in solid substrate fermentation (SSF. The wheat bran concentration and incubation period were significant factors. The process parameters optimized with response surface methodology was wheat bran concentration 400 g/L; pH, 6.5; temperature, 400C and incubation period 5 days when inoculum 10 % (1x107 cells/ ml was used for cellulase production in SSF. Supplementation of lactose and CMC to the wheat bran medium favored the enzyme formation.

  9. 漾濞大泡核桃WRKY转录因子基因JsWRKY1的克隆及表达特性分析%Cloning and Expression Analysis of a WRKY Gene JsWRKY1 from Juglans sigillata

    Institute of Scientific and Technical Information of China (English)

    张南南; 陈朝银; 季博; 何华; 韩青; 葛锋; 刘迪秋

    2014-01-01

    WRKY转录因子普遍存在于植物体内,在植物的抗病防御反应中起重要作用。本实验基于漾濞大泡核桃(Juglans sigillata)中编码WRKY转录因子的EST序列设计引物,采用快速扩增cDNA末端技术,克隆得到一个新的WRKY基因的全长cDNA序列,命名为JsWRKY1(KJ170895)。JsWRKY1的cDNA全长为1012 bp,含有564 bp的开放阅读框,154 bp 5'-非翻译区以及294 bp的3′-非翻译区,编码具有187个氨基酸的蛋白质。JsWRKY1编码的氨基酸序列与已知植物WRKY家族成员间的同源性和聚类分析表明JsWRKY1与来源于可可树(Theobroma cacao)和大豆(Glycine max)中的WRKY相似性较高,属于IIc类WRKY。qRT-PCR分析结果显示,信号分子水杨酸、茉莉酸、H2O2和乙烯处理可以不同程度地诱导漾濞大泡核桃叶片中JsWRKY1的表达。此外,接种胶孢炭疽菌后JsWRKY1的表达量迅速上升,在接种后4 h时达到最高水平,之后表达量逐渐下降,暗示JsWRKY1参与漾濞大泡核桃抗胶孢炭疽菌的防卫反应。%The WRKY transcription factors are ubiquitous in plants and play important roles in the defense re-sponses. A WRKY EST was isolated from Juglans sigillata, and the full-length cDNA of the EST was cloned with the method of rapid ampliifcation of cDNA ends and named as JsWRKY1 (KJ170895). JsWRKY1 was 1 012 bp in length and contained an intact open reading frame (ORF) of 564 bp, a 154 bp 5′-untranslated region (UTR), and a 294 bp 3′-UTR. The predicted protein of JsWRKY1 with 187 amino acid residues shared high similarity with the WRKYs from Theobroma cacao and Glycine max. Moreover, the JsWRKY1 fell into the group IIc of WRKYs through phylogenetic analysis. qRT-PCR analysis showed that the expression of JsWRKY1 was induced by salicylic acid, jasmonic acid, H2O2, and ethylene. Morever, JsWRKY1 was quickly induced after inoculation with Colletorichum gloeosporidies, and the highest transcription level was achieved at 4 h post in-oculation, then

  10. Genomic sequence analysis and biological characteristics of a rescued clone of avian leukosis virus strain JS11C1, isolated from indigenous chickens.

    Science.gov (United States)

    Cui, Ning; Su, Shuai; Chen, Zimeng; Zhao, Xiaomin; Cui, Zhizhong

    2014-11-01

    The strain JS11C1, a member of a putative new subgroup of avian leukosis virus (ALV) that is different from all six known subgroups from chickens based on Gp85 amino acid sequence comparison, was isolated from Chinese native chicken breeds in 2012. In order to further study the genome structure, biological characteristics, and the evolutionary relationship of the virus with others of known subgroups from infected chickens, we determined the complete genome sequence, constructed an infectious clone of ALV strain JS11C1, and performed comparative analysis using the whole genome sequence or elements with that of other ALVs available in GenBank. The results showed that the full-length sequence of the JS11C1 DNA provirus genome was 7707 bp, which is consistent with a genetic organization typical of a replication-competent type C retrovirus lacking viral oncogenes. The rescued infectious clone of JS11C1 showed similar growth rate and biological characteristics to its original virus. All the comparison analyses based on whole genomes support the opinion that the new isolates are relatively distantly related to any known subgroups of ALVs and might be classified as a new subgroup.

  11. THE AMERICAN PROPHET: THE INFLUENCE OF THE PROPHETIC ON MARTIN LUTHER KING JR

    OpenAIRE

    Ritchie, David T.

    2010-01-01

    The foundations of U.S. civil rights pioneer Martin Luther King Jr.’s thought are as variedand diverse as his vision for a new American society. As a Baptist minister his ideas were of courseshaped by the Christian ideals of that faith. He was also influenced, however, by religious and secularideals from other traditions. In this article I discuss the effect of the work of the Jewish theologian andsocial philosopher Martin Buber on King’s philosophy. In particular, I examine how Buber’s notio...

  12. In Memoriam of John T. Yates Jr. (August 3, 1935 - September 26, 2015)

    Science.gov (United States)

    Russell, John N.; Beebe, Thomas P.

    2016-10-01

    John T. Yates, Jr., Professor of Chemistry at the University of Virginia, member of the US National Academy of Sciences, and a pioneer of modern surface science, passed away at his home on Saturday morning September 26, 2015, from a recurring glioblastoma. John was both courageous, pragmatic and forthright about his diagnosis right to the end. His wife, Kerin, related that John, upon learning of his diagnosis, said that he had had a great life and was not going to 'let the last 1.25%' define him. It did not. He had a wonderful family and a stellar career.

  13. 漾濞大泡核桃WRKY转录因子基因JsWRKY1的克隆及表达特性分析

    Institute of Scientific and Technical Information of China (English)

    张南南; 陈朝银; 季博; 何华; 韩青; 葛锋; 刘迪秋

    2014-01-01

    WRKY转录因子普遍存在于植物体内,在植物的抗病防御反应中起重要作用。本实验基于漾濞大泡核桃(Juglans sigillata)中编码WRKY转录因子的EST序列设计引物,采用快速扩增cDNA末端技术,克隆得到一个新的脓Ky基因的全长cDNA序列,命名为JsWRKY1(KJ170895)。JsWRKY1的cDNA全长为1012bp,含有564bp的开放阅读框,154bp 5’-非翻译区以及294bp的3'-非翻译区,编码具有187个氨基酸的蛋白质。JsWRKY1编码的氨基酸序列与已知植物WRKY家族成员间的同源性和聚类分析表明JsWRKY1与来源于可可树(Theobroma cacao)和大豆(Glycinemax)中的wRKY相似性较高,属于IIc类wRKY。qRT-PCR分析结果显示,信号分子水杨酸、茉莉酸、H2O2和乙烯处理可以不同程度地诱导漾濞大泡核桃叶片中JsWRKY1的表达。此外,接种胶孢炭疽菌后JsWRKY1的表达量迅速上升,在接种后4h时达到最高水平,之后表达量逐渐下降,暗示JsWRKY1参与漾濞大泡核桃抗胶孢炭疽菌的防卫反应。

  14. Suzaku observations of the hard X-ray spectrum of Vela Jr

    CERN Document Server

    Takeda, Sawako; Terada, Yukikatsu; Tashiro, Makoto S; Katsuda, Satoru; Yamazaki, Ryo; Ohira, Yutaka; Iwakiri, Wataru

    2016-01-01

    We report the results of Suzaku observations of the young supernova remnant, Vela Jr.\\ (RX J0852.0$-$4622), which is known to emit synchrotron X-rays, as well as TeV gamma-rays. Utilizing 39 Suzaku mapping observation data from Vela Jr., a significant hard X-ray emission is detected with the hard X-ray detector (HXD) from the north-west TeV-emitting region. The X-ray spectrum is well reproduced by a single power-law model with the photon index of 3.15$^{+1.18}_{-1.14}$ in the 12--22 keV band. Compiling this with the soft X-ray spectrum simultaneously observed with the X-ray imaging spectrometer (XIS) onboard Suzaku, we find that the wide-band X-ray spectrum in the 2--22 keV band is reproduced with a single power-law or concave broken power-law model, which are statistically consistent with each other. Whichever the model of a single or broken power-law is appropriate, clearly the spectrum has no rolloff structure. Applying this result to the method introduced in \\citet{yama2014}, we find that one-zone synchro...

  15. The leadership principles of Dr. Martin Luther King, Jr. and their relevance to surgery.

    Science.gov (United States)

    Brunicardi, F Charles; Cotton, Ronald T; Cole, George W; Martinez, George

    2007-01-01

    In order to face the challenges in healthcare this century, it is essential that surgeons understand modern leadership principles. One of the greatest leaders in history was Dr. Martin Luther King, Jr., who provides a shining example of level-5 leadership for us to study. The study of leadership principles of great leaders can provide us with practical methods of conflict resolution as well as inspiration to keep us engaged and focused. As leaders of the medical community, we face numerous challenges, including discovering and implementing new treatments for disease, providing care for the indigent, overcoming educational challenges such as incorporating the ACGME Core Competencies into our surgical training and promoting diversity in education. Achieving these goals is often hindered by the environment in which we labor-nearly 50 million are uninsured, the rising cost of medical care is currently at 16% of the GNP, and reimbursement rates are falling-which makes the practice of surgery a significant challenge. Effective leadership will be paramount in achieving these goals. In this editorial, which summarizes a presentation given to the Surgical Section of the annual National Medical Association meeting, five important leadership principles that are important for surgeons have been selected and related to the outstanding leadership of Dr. Martin Luther King, Jr.

  16. Current Perioperative Management of Anticoagulant and Antiplatelet Use in Neuroendovascular Therapy: Analysis of JR-NET1 and 2

    Science.gov (United States)

    ENOMOTO, Yukiko; YOSHIMURA, Shinichi; SAKAI, Nobuyuki; EGASHIRA, Yusuke

    2014-01-01

    To evaluate current perioperative antithrombotic management in neuroendovascular therapy in Japan, we analyzed perioperative anticoagulant and antiplatelet use in various procedures and examined their relationships with periprocedural adverse events. Patient's data from nationwide surveys administered by the Japanese Registry of Neuroendovascular Therapy (JR-NET) between January 2005 and December 2007 (JR-NET1) and January 2008 and December 2009 (JR-NET2) were retrospectively analyzed. Compared to JR-NET1, the frequency of perioperative antiplatelet therapy and dual or triple therapy were increased for either aneurysm coiling and percutaneous transluminal angioplasty or stenting in JR-NET2. Although ischemic complications were significantly decreased (4.2% vs. 2.1%, p antiplatelet therapy (preoperative: 5.3% vs. 9.2%, p therapy was performed more frequently and intensively in neuroendovascular therapy in Japan. While ischemic complications were decreased, hemorrhagic complications and severe adverse events were increased. These results suggest that intensive antithrombotic therapy has a potential risk of hemorrhagic complications for Japanese patients. PMID:24305029

  17. Construction of High Performance Instant Messaging System Based on Socket.io+Node.js+Redis%基于Socket.io+Node.js+Redis构建高效即时通讯系统

    Institute of Scientific and Technical Information of China (English)

    黄经赢

    2014-01-01

    随着互联网技术的发展,市场上已有一些比较成熟的即时通讯系统,但大多数都是基于C/S结构,而基于B/S结构的即时通讯系统还处于发展阶段,主要受制于不同浏览器版本的兼容问题,且该类系统对高并发和数据快速存取有着较高的要求。而基于Socket.io、Node.js和Redis的技术,可以较好地解决B/S结构所遇到的问题。%With the development of Internet, there have been some mature instant messaging systems on the market, but most of them are based on C/S structure, the instant messaging system based on B/S structure is still developing, the main reason is subject to the different versions of browser compatibility issues, and the instant messaging system require high concurrency and fast data access. Based on Socket.io, Node.js and Redis technology can be better to solve the problem of B/S structure encountered.

  18. 禽腺病毒江苏株(JS)复制非必需片段的确定%Identification of Non-essential Region for Fowl Adenovirus Replication of JS Strain

    Institute of Scientific and Technical Information of China (English)

    何秀苗; 秦爱建; 刘岳龙; 金文杰

    2004-01-01

    利用PCR方法从一株Ⅰ群禽腺病毒的分离物(FAVI-JS)中扩增出其基因组的两个末端L片段和r片段、ITR片段,并分别克隆进pGEM-T easy载体,然后将L片段、r片段和ITR片段同时克隆进pHC粘粒载体中,获得质粒pHC-FAVI-r-ITR-L,再在该克隆片段中插入增强型绿色荧光蛋白(eGFP)基因,获得转移质粒载体pFAVI-eGFP.将pFAVI-eGFP转染已被该野生型Ⅰ群禽腺病毒分离物感染了的鸡胚肾细胞进行同源重组,通过无限稀释法筛选重组病毒,结果获得了表达增强型绿色荧光蛋白的重组Ⅰ群禽腺病毒rFAVI-eGFP,证明位于基因组右末端r片段和ITR片段之间的位点为病毒复制非必需区,为禽腺病毒的重组基因工程疫苗的研究奠定了基础.

  19. Book review: Martin’s dream: my journey and the legacy of Martin Luther King Jr.\\ud

    OpenAIRE

    McCormick, Roger

    2013-01-01

    "Martin’s Dream: My Journey and the Legacy of Martin Luther King Jr." Clayborne Carson. Palgrave Macmillan. January 2013. --- \\ud Written with the unique perspective of someone who has, for three decades, been involved with Martin Luther King Jr.’s legacy, Clayborne Carson gives readers an insider’s account of what transpired after the Dream speech, and beyond. A rich and engrossing memoir of black empowerment at a unique moment in time, this is an undoubtedly special contribution to King’s m...

  20. An initial survey of the cattle grub Dermatobia hominis (L. Jr.) in Nicaragua.

    Science.gov (United States)

    Villarino, Mario A; Garcia, Omar; Fussell, Weyman; Preston, Kelly; Wagner, Gale G

    2003-12-12

    After the civil war and the Hurricane-Mitch disaster, cattlemen in Nicaragua were forced to transport their cattle from lowland areas to higher, dryer areas of the country. These areas are natural ecological niches for the cattle grub Dermatobia hominis (L. Jr.) (Diptera: Cuterebridae). To determine the importance of this infestation, the Agricultural and Livestock-Forestry Ministry selected a central area of Nicaragua to run a pioneer survey program to acquire information about hosts involved, number of cases, treatments applied and general knowledge of 42 farmers about the life cycle of the parasite. The subjects were either farm owners or farm managers. Ninety-five percentage of the farms indicated cases of D. hominis infestation in their animals, with cattle being the most affected host (100% of the affected farms). There was poor understanding of the D. hominis life cycle, vectors and control methods. A misuse of insecticides for the treatment of larval infestation by D. hominis was indicated.

  1. Possessing History and American Innocence: James Baldwin, William F. Buckley, Jr., and the 1965 Cambridge Debate

    Directory of Open Access Journals (Sweden)

    Daniel Robert McClure

    2016-12-01

    Full Text Available The 1965 debate at Cambridge University between James Baldwin and William F. Buckley, Jr., posed the question: “Has the American Dream been achieved at the Expense of the American Negro?” Within the contours of the debate, Baldwin and Buckley wrestled with the ghosts of settler colonialism and slavery in a nation founded on freedom and equality. Framing the debate within the longue durée, this essay examines the deep cultural currents related to the American racial paradox at the height of the Civil Rights movement. Underscoring the changing language of white resistance against black civil rights, the essay argues that the Baldwin and Buckley debate anticipated the ways the U.S. would address racial inequality in the aftermath of the civil rights era and the dawn of neoliberalism in the 1970s.

  2. Collected Papers in Structural Mechanics Honoring Dr. James H. Starnes, Jr.

    Science.gov (United States)

    Knight, Norman F., Jr. (Compiler); Nemeth, Michael P. (Compiler); Malone, John B. (Compiler)

    2006-01-01

    This special publication contains a collection of structural mechanics papers honoring Dr. James H. Starnes, Jr. presented at the 46th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference held in Austin, Texas, April 18-21, 2005. Contributors to this publication represent a small number of those influenced by Dr. Starnes' technical leadership, his technical prowess and diversity, and his technical breath and depth in engineering mechanics. These papers cover some of the research areas Dr. Starnes investigated, which included buckling, postbuckling, and collapse of structures; composite structural mechanics, residual strength and damage tolerance of metallic and composite structures; and aircraft structural design, certification and verification. He actively pursued technical understanding and clarity, championed technical excellence, and modeled humility and perseverance.

  3. Julius H. Comroe, Jr., distinguished lecture: central chemoreception: then ... and now.

    Science.gov (United States)

    Nattie, Eugene

    2011-01-01

    The 2010 Julius H. Comroe, Jr., Lecture of the American Physiological Society focuses on evolving ideas in chemoreception for CO₂/pH in terms of what is "sensed," where it is sensed, and how the sensed information is used physiologically. Chemoreception is viewed as involving neurons (and glia) at many sites within the hindbrain, including, but not limited to, the retrotrapezoid nucleus, the medullary raphe, the locus ceruleus, the nucleus tractus solitarius, the lateral hypothalamus (orexin neurons), and the caudal ventrolateral medulla. Central chemoreception also has an important nonadditive interaction with afferent information arising at the carotid body. While ventilation has been viewed as the primary output variable, it appears that airway resistance, arousal, and blood pressure can also be significantly affected. Emphasis is placed on the importance of data derived from studies performed in the absence of anesthesia.

  4. Gunshot wounds to the hand. The Martin Luther King, Jr, General Hospital experience.

    Science.gov (United States)

    Phillips, P; Hansraj, K K; Cox, E E; Ashley, E M

    1995-01-01

    This article is a retrospective review of patients who presented to Martin Luther King, Jr./Drew Medical Center with gunshot wounds and had either isolated or associated injuries to the hand. The following is an account of those injuries noting the location, soft-tissue or bony involvement, and interventional methods that were implemented in the treatment of these patients who resided primarily in South Central Los Angeles. Prompt evaluation and initiation of treatment is essential in the management of both high- and low-velocity gunshot wounds so as to decrease the potential morbidity that often follows. Society must also look at the prevalence of these injuries and address the underlying issues that often are the root of the acts of violence.

  5. Biosensor for Direct Determination of Fenitrothion and EPN Using Recombinant Pseudomonas putida JS444 with Surface Expressed Organophosphorus Hydrolase. 1. Modified Clark Oxygen Electrode

    Directory of Open Access Journals (Sweden)

    Ashok Mulchandani

    2006-04-01

    Full Text Available This paper reports a first microbial biosensor for rapid and cost-effectivedetermination of organophosphorus pesticides fenitrothion and EPN. The biosensorconsisted of recombinant PNP-degrading/oxidizing bacteria Pseudomonas putida JS444anchoring and displaying organophosphorus hydrolase (OPH on its cell surface asbiological sensing element and a dissolved oxygen electrode as the transducer. Surface-expressed OPH catalyzed the hydrolysis of fenitrothion and EPN to release 3-methyl-4-nitrophenol and p-nitrophenol, respectively, which were oxidized by the enzymaticmachinery of Pseudomonas putida JS444 to carbon dioxide while consuming oxygen,which was measured and correlated to the concentration of organophosphates. Under theoptimum operating conditions, the biosensor was able to measure as low as 277 ppb offenitrothion and 1.6 ppm of EPN without interference from phenolic compounds and othercommonly used pesticides such as carbamate pesticides, triazine herbicides andorganophosphate pesticides without nitrophenyl substituent. The applicability of thebiosensor to lake water was also demonstrated.

  6. 基于Web的远程内容调用技术-Web JS%Content Remote Call Technology Based on Web

    Institute of Scientific and Technical Information of China (English)

    胡飞

    2012-01-01

    WEB JS, a up-to-date technology, draws content from remote server. Comparing with WEB Service technology, it is better in such fields as Operating and Coding. This technology will help people gain high performance.%作为云计算技术之一的远程内容调用技术,常规的做法是通过Web Service等技术实现.本文提出一种全新的调用技术:Web JS.该技术和前面的技术相比有操作简单、无须动态网页编程经验等诸多好处.

  7. Biosensor for Direct Determination of Fenitrothion and EPN Using Recombinant Pseudomonas putida JS444 with Surface Expressed Organophosphorus Hydrolase. 1. Modified Clark Oxygen Electrode

    OpenAIRE

    2006-01-01

    This paper reports a first microbial biosensor for rapid and cost-effective determination of organophosphorus pesticides fenitrothion and EPN. The biosensor consisted of recombinant PNP-degrading/oxidizing bacteria Pseudomonas putida JS444 anchoring and displaying organophosphorus hydrolase (OPH) on its cell surface as biological sensing element and a dissolved oxygen electrode as the transducer. Surface-expressed OPH catalyzed the hydrolysis of fenitrothion and EPN to release 3-methyl-4-nitr...

  8. A Two-Component Monooxygenase Catalyzes Both the Hydroxylation of p-Nitrophenol and the Oxidative Release of Nitrite from 4-Nitrocatechol in Bacillus sphaericus JS905

    OpenAIRE

    Kadiyala, Venkateswarlu; Spain, Jim C.

    1998-01-01

    Bacteria that metabolize p-nitrophenol (PNP) oxidize the substrate to 3-ketoadipic acid via either hydroquinone or 1,2,4-trihydroxybenzene (THB); however, initial steps in the pathway for PNP biodegradation via THB are unclear. The product of initial hydroxylation of PNP could be either 4-nitrocatechol or 4-nitroresorcinol. Here we describe the complete pathway for aerobic PNP degradation by Bacillus sphaericus JS905 that was isolated by selective enrichment from an agricultural soil in India...

  9. Pragmatic Analyses of Martin Luther King (Jr)'s Speech: "I Have a Dream"--An Introspective Prognosis

    Science.gov (United States)

    Josiah, Ubong E.; Oghenerho, Gift

    2015-01-01

    This paper investigates the speech of Martin Luther King (Jr.) titled: "I Have a Dream", presented in 1963 at the Lincoln Memorial. This speech is selected for use because it involves a speaker and an audience who belong to a particular speech community. The speech is about the failed promises by the Americans whose dream advocate…

  10. Crystallization and preliminary X-ray crystallographic analysis of polyphenol oxidase from Juglans regia (jrPPO1)

    Energy Technology Data Exchange (ETDEWEB)

    Zekiri, Florime; Bijelic, Aleksandar; Molitor, Christian; Rompel, Annette, E-mail: annette.rompel@univie.ac.at [Universität Wien, Althanstrasse 14, 1090 Wien (Austria)

    2014-05-28

    The crystallization and preliminary X-ray crystallographic analysis of a plant PPO exhibiting monophenolase activity from J. regia (jrPPO1) in its active form (Asp{sup 101}–Arg{sup 445}) are reported. Tyrosinase is a type 3 copper enzyme that catalyzes the ortho-hydroxylation of monophenols to diphenols as well as their subsequent oxidation to quinones, which are precursors for the biosynthesis of melanins. The first plant tyrosinase from walnut leaves (Juglans regia) was purified to homogeneity and crystallized. During the purification, two forms of the enzyme differing only in their C-termini [jrPPO1(Asp{sup 101}–Pro{sup 444}) and jrPPO1(Asp{sup 101}–Arg{sup 445})] were obtained. The most abundant form jrPPO1(Asp{sup 101}–Arg{sup 445}), as described in Zekiri et al. [Phytochemistry (2014 ▶), 101, 5–15], was crystallized, resulting in crystals that belonged to space group C121, with unit-cell parameters a = 115.56, b = 91.90, c = 86.87 Å, α = 90, β = 130.186, γ = 90°, and diffracted to 2.39 Å resolution. Crystals were only obtained from solutions containing at least 30% polyethylene glycol 5000 monomethyl ether in a close-to-neutral pH range.

  11. "God and Man at Yale" and beyond: The Thoughts of William F. Buckley, Jr. on Higher Education, 1949-1955

    Science.gov (United States)

    Green, James

    2012-01-01

    The March 24, 2008, edition of "National Review" (NR) was dedicated to the memory of its founder: William F. Buckley, Jr., who had passed away on February 27, 2008. It included thirty two different memorials about him written by prominent authors, editors, social commentators, fellow journalists, politicians, and historians. Then NR…

  12. Health Care Fraud: Characteristics, Sanctions, and Prevention. Briefing Report to the Honorable William V. Roth, Jr., U.S. Senate.

    Science.gov (United States)

    General Accounting Office, Washington, DC. Accounting and Financial Management Div.

    At the request of Senator William Roth, Jr., the General Accounting Office (GAO) reviewed Medicare and Medicaid fraud investigations that agency inspectors general referred to the Department of Justice for prosecution to identify characteristics of alleged fraud against the government and to determine actions taken against those caught defrauding…

  13. The Limits of Master Narratives in History Textbooks: An Analysis of Representations of Martin Luther King, Jr.

    Science.gov (United States)

    Alridge, Derrick P.

    2006-01-01

    In this study, I argue that American history textbooks present discrete, heroic, one-dimensional, and neatly packaged master narratives that deny students a complex, realistic, and rich understanding of people and events in American history. In making this argument, I examine the master narratives of Martin Luther King, Jr., in high school history…

  14. Toward a Modern Synthesis of Immunity: Charles A. Janeway Jr. and the Immunologist’s Dirty Little Secret

    Science.gov (United States)

    Gayed, Peter M.

    2011-01-01

    This essay chronicles the major theoretical and experimental contributions made by Charles A. Janeway, Jr. (1943-2003), Howard Hughes Medical Institute investigator and Yale Professor of Immunobiology, who established the fundamental role of the innate immune system in the induction of the adaptive arm. PMID:21698045

  15. Toward a Modern Synthesis of Immunity: Charles A. Janeway Jr. and the Immunologist’s Dirty Little Secret

    OpenAIRE

    Gayed, Peter M.

    2011-01-01

    This essay chronicles the major theoretical and experimental contributions made by Charles A. Janeway, Jr. (1943-2003), Howard Hughes Medical Institute investigator and Yale Professor of Immunobiology, who established the fundamental role of the innate immune system in the induction of the adaptive arm.

  16. Fetal and neonatal anemia associated with anti-Jr(a) : a case report showing a poorly hemolytic mechanism.

    Science.gov (United States)

    Sasamoto, Naoko; Tomimatsu, Takuji; Nagamine, Keisuke; Oshida, Machiko; Kashiwagi, Hirokazu; Koyama, Shinsuke; Kanagawa, Takeshi; Arahori, Hitomi; Tomiyama, Yoshiaki; Kimura, Tadashi

    2011-08-01

    Although recently published case reports suggest the significance of Jr(a) alloimmunization in the obstetric setting, the involved mechanism still remains unclear. Here we report a case of severe fetal and neonatal anemia associated with anti-Jr(a) alloimmunization, which was successfully managed using Doppler assessment of peak systolic velocity of the fetal middle cerebral artery (MCA-PSV). A Japanese woman with anti-Jr(a) (titer 1024) was referred to our department at 20 weeks' gestation. As fetal MCA-PSV exceeded 1.5 multiple of median, labor was induced and a female neonate of 1998 g was delivered vaginally at 33 weeks and 5 days of gestation. The infant's hematocrit and hemoglobin levels were 25.4% and 82 g/L, respectively, but her total bilirubin level (15 µmol/L; 0.9 mg/dL) and reticulocyte counts (4.5%) were low. During the course, the infant showed no apparent signs of hemolysis. Jr(a) alloimmunization should be recognized as a possible cause of fetal anemia with no direct hemolytic process. © 2011 The Authors. Journal of Obstetrics and Gynaecology Research © 2011 Japan Society of Obstetrics and Gynecology.

  17. Human Progress Never Rolls in on Wheels of Inevitability: Biographies of Martin Luther King, Jr., in the Classroom.

    Science.gov (United States)

    Kazemek, Francis E.

    1990-01-01

    Presents resources for teaching about Dr. Martin Luther King, Jr. Outlines criteria for selecting biographies for children and young adults. Identifies problems in certain biographies of King, and recommends high quality biographies of King. Discusses exercises for integrating themes from King's life into the classroom. (RW)

  18. Pretext, Context, Subtext: Textual Power in the Writing of Langston Hughes, Richard Wright, and Martin Luther King, Jr.

    Science.gov (United States)

    Bogumil, Mary L.; Molino, Michael R.

    1990-01-01

    Studies verbal pretexts, social subtexts, and interpretive contexts of works by Langston Hughes, Richard Wright, and Martin Luther King, Jr. Notes that cultural repression is propagated (and dispelled) in part through the power of language. Notes that these texts are relevant for teaching textual power in hopes of affecting social change. (RS)

  19. [Isolation and identification of a bacterial strain JS018 capable of degrading several kinds of organophosphate pesticides].

    Science.gov (United States)

    Jiang, Yu-Ji; Deng, You-Jin; Liu, Xin-Rui; Xie, Bao-Gui; Hu, Fang-Ping

    2006-06-01

    Organophosphate pesticides are used widely all over the world and play an important role in plant pest control. However these pesticides are considered as pollutants and harmful to human health. To search for microorganisms that can degrade organophosphate pesticides with high efficiency, a bacterial strain, coded as JS018, was isolated and screened from the soil in the vicinity of Shanming Pesticides Factory, Shanming, Fujian. Laboratory tests showed that the bacterium could degrade several kinds of organophosphate pesticides, such as Parathion-methyl and phoxin. The strain's degrading rates on phoxin, Parathion-methyl, hostathion and dichlorvos in LB liquid fermentation medium for 36 h were 99%, 96%, 80.4% and 69.0% respectively. The bacterial colonies on LB plate appeared shiny and pale-pink in color. The bacteria were Gram-negative coccoids, 0.5 - 0.7 microm in diameter. They grew well at 30 - 38 degrees C and pH 7.0 - 9.0. The optimal temperature and pH for cell growth was 32 degrees C and pH 7.5 - 8.0, respectively. They did not grow in medium containing 6% or more NaCl. The antibiotic susceptibility tests showed that the strain was resistant to ampicillin, penicillin and lincomycin. It was sensitive to kanamycin, tetracycline and gentamicin. Laboratory tests also showed that the strain could ferment D-glucose, trehalose, melezitose and ethanol. It was negative in the production of indole and hydrogen sulfide. It could not liquefy gelatin, utilize citrate, nor ferment L-arabinose, sucrose, D-mannitol, D-xylose, fructose, D-galactose, maltose or lactose. The catalase, urease and nitrate reduction were positive. Based on its morphological, physiological and biochemical properties as well as the 16S rDNA sequence analysis result, the strain was tentatively identified as Roseomonas sp.

  20. Interactive Visualization of Near Real-Time and Production Global Precipitation Mission Data Online Using CesiumJS

    Science.gov (United States)

    Lammers, M.

    2016-12-01

    Advancements in the capabilities of JavaScript frameworks and web browsing technology make online visualization of large geospatial datasets viable. Commonly this is done using static image overlays, pre-rendered animations, or cumbersome geoservers. These methods can limit interactivity and/or place a large burden on server-side post-processing and storage of data. Geospatial data, and satellite data specifically, benefit from being visualized both on and above a three-dimensional surface. The open-source JavaScript framework CesiumJS, developed by Analytical Graphics, Inc., leverages the WebGL protocol to do just that. It has entered the void left by the abandonment of the Google Earth Web API, and it serves as a capable and well-maintained platform upon which data can be displayed. This paper will describe the technology behind the two primary products developed as part of the NASA Precipitation Processing System STORM website: GPM Near Real Time Viewer (GPMNRTView) and STORM Virtual Globe (STORM VG). GPMNRTView reads small post-processed CZML files derived from various Level 1 through 3 near real-time products. For swath-based products, several brightness temperature channels or precipitation-related variables are available for animating in virtual real-time as the satellite observed them on and above the Earth's surface. With grid-based products, only precipitation rates are available, but the grid points are visualized in such a way that they can be interactively examined to explore raw values. STORM VG reads values directly off the HDF5 files, converting the information into JSON on the fly. All data points both on and above the surface can be examined here as well. Both the raw values and, if relevant, elevations are displayed. Surface and above-ground precipitation rates from select Level 2 and 3 products are shown. Examples from both products will be shown, including visuals from high impact events observed by GPM constellation satellites.

  1. Maksuameti ja Paltsi PR-sõda leevenemas / Toomas Mattson

    Index Scriptorium Estoniae

    Mattson, Toomas, 1970-

    2003-01-01

    Maksuameti ajutine juht Aivar Rehe tegi suhtekorraldusfirmale Alfa Omega Communications ettepaneku lõpetada PR-leping. Rahandusminister Tõnis Paltsi nõustamisest. Vt. samas lühiintervjuud Tõnis Paltsiga: Palts: Olin üksi lahinguväljal. Lisad: Tõnis Paltsi ja Maksuameti vägikaikaveo kronoloogia

  2. Maksuameti ja Paltsi PR-sõda leevenemas / Toomas Mattson

    Index Scriptorium Estoniae

    Mattson, Toomas, 1970-

    2003-01-01

    Maksuameti ajutine juht Aivar Rehe tegi suhtekorraldusfirmale Alfa Omega Communications ettepaneku lõpetada PR-leping. Rahandusminister Tõnis Paltsi nõustamisest. Vt. samas lühiintervjuud Tõnis Paltsiga: Palts: Olin üksi lahinguväljal. Lisad: Tõnis Paltsi ja Maksuameti vägikaikaveo kronoloogia

  3. Eesti tahab hajutada venelaste kiusaja muljet / Toomas Mattson

    Index Scriptorium Estoniae

    Mattson, Toomas, 1970-

    1995-01-01

    Diagramm: Väljamigratsioon Eestist 1995.a. Väljamigratsioon Eestist 1989-1994. Järgneb 30. okt. 1995, lk. 5. Ilmunud ka: Vetshernije Vesti, 31. okt. 1995, lk. 9; 1. nov. 1995, lk. 9; 2. nov. 1995, lk. 9

  4. Backbone.js essentials

    CERN Document Server

    Walker, Jeremy

    2015-01-01

    If you are a developer with baseline JavaScript proficiency and are familiar with the jQuery library, then this book is ideal for you. Whether you've tried building complex web applications before and been frustrated by the challenge of doing so without the proper tools, or whether you've only built simple websites and are now looking to create full-featured web applications, this book has everything you need to get ahead of the curve.

  5. Backbone.js cookbook

    CERN Document Server

    Mirgorod, Vadim

    2013-01-01

    Written in a friendly, example driven Beginner's Guide format, there are plenty of step-by-step instructions to get you started fast!Pentaho 4.0 By Example: Beginner's Guide is the ideal companion for a wide-variety of developers. Whether you are new to the world of Business Intelligence reporting, or an experienced BI analyst, this book will guide you through the creation of your first reports in Pentaho. We assume some knowledge of the SQL language and database systems.

  6. Testing Backbone.js

    CERN Document Server

    Roemer, Ryan

    2013-01-01

    This book is packed with the step by step tutorial and instructions in recipe format helping you setup test infrastructure and gradually advance your skills to plan, develop, and test your backbone applications.If you are a JavaScript developer looking for recipes to create and implement test support for your backbone application, then this book is ideal for you.

  7. KnockoutJS essentials

    CERN Document Server

    Ferrando, Jorge

    2015-01-01

    If you are a JavaScript developer who has been using DOM manipulation libraries such as Mootools or Scriptaculous, and you want go further in modern JavaScript development with a simple and well-documented library, then this book is for you. Learning how to use Knockout will be perfect as your next step towards building JavaScript applications that respond to user interaction.

  8. Mastering Node.js

    CERN Document Server

    Pasquali, Sandro

    2013-01-01

    This book contains an extensive set of practical examples and an easy-to-follow approach to creating 3D objects.This book is great for anyone who already knows JavaScript and who wants to start creating 3D graphics that run in any browser. You don't need to know anything about advanced math or WebGL; all that is needed is a general knowledge of JavaScript and HTML. The required materials and examples can be freely downloaded and all tools used in this book are open source.

  9. J-R Curve Determination for Disk-shaped Compact Specimens Based on the Normalization Method and Direct Current Potential Drop Technique

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Xiang [ORNL; Nanstad, Randy K [ORNL; Sokolov, Mikhail A [ORNL

    2014-01-01

    Material ductile fracture toughness can be described by J-integral versus crack extension relationship (J-R curve). As a conventional J-R curve measurement method, unloading compliance (UC) becomes impractical in elevated temperature testing due to relaxation of the material and a friction induced back-up shape of the J-R curve. In addition, the UC method may underpredict the crack extension for standard disk-shaped compact (DC(T)) specimens. In order to address these issues, the normalization method and direct current potential drop (DCPD) technique were applied for determining J-R curves at 24 C and 500 C for 0.18T DC(T) specimens made from type 316L stainless steel. For comparison purchase, the UC method was also applied in 24 C tests. The normalization method was able to yield valid J-R curves in all tests. The J-R curves from the DCPD technique need adjustment to account for the potential drop induced by plastic deformation, crack blunting, etc. and after applying a newly-developed DCPD adjustment procedure, the post-adjusted DCPD J-R curves essentially matched J-R curves from the normalization method. In contrast, the UC method underpredicted the crack extension in all tests resulting in substantial deviation in the derived J-R curves manifested by high Jq values than the normalization or DCPD method. Only for tests where the UC method underpredicted the crack extension by a very small value, J-R curves determined by the UC method were similar to those determined by the normalization or DCPD method.

  10. General Charles F. Bolden, Jr. and Professor Claude Nicollier reunite during visit to CERN

    CERN Multimedia

    Jordan Juras

    2011-01-01

    Thursday 23 June, CERN saw an unlikely and much savoured meeting between two old colleagues and friends: General Charles F. Bolden, Jr. and Professor Claude Nicollier.   Bolden and Nicollier were separately invited to CERN for different reasons - Charles Bolden had been invited by Professor Samuel Ting to visit the newly built and now fully operational Payload Operation and Control Centre of the AMS collaboration and Claude Nicollier had been invited by the Theory Department to give a colloquium. They were delightfully surprised when they met at the entrance of the main building. Bolden and Nicollier served together in the Space Shuttle Program and were trained by NASA during the 1980’s where they became close friends. On 24 April, 1990, Bolden piloted the Space Shuttle Discovery into orbit with the Hubble telescope in the payload bay. Though Nicollier did not accompany Bolden during the Hubble launch, he did return to the telescope 3 years later on board the Space Shuttle Ende...

  11. Plutino 15810 (1994 JR1), an accidental quasi-satellite of Pluto

    CERN Document Server

    Marcos, C de la Fuente

    2012-01-01

    In the solar system, quasi-satellites move in a 1:1 mean motion resonance going around their host body like a retrograde satellite but their mutual separation is well beyond the Hill radius and the trajectory is not closed as they orbit the Sun not the host body. So far, minor bodies temporarily trapped in the quasi-satellite dynamical state have been identified around Venus, Earth, the dwarf planet (1) Ceres, the large asteroid (4) Vesta, Jupiter, Saturn and Neptune. Using computer simulations, Tiscareno and Malhotra have predicted the existence of a small but significant population of minor bodies moving in a 1:1 mean motion resonance with Pluto. Here we show using N-body calculations that the Plutino 15810 (1994 JR1) is currently an accidental quasi-satellite of Pluto and it will remain as such for nearly 350,000 yr. By accidental we mean that the quasi-satellite phase is triggered (or terminated) not by a direct gravitational influence in the form of a discrete close encounter but as a result of a resonan...

  12. The Manuel Lujan Jr. Neutron Scattering Center (LANSCE) experiment reports 1993 run cycle. Progress report

    Energy Technology Data Exchange (ETDEWEB)

    Farrer, R.; Longshore, A. [comps.

    1995-06-01

    This year the Manuel Lujan Jr. Neutron Scattering Center (LANSCE) ran an informal user program because the US Department of Energy planned to close LANSCE in FY1994. As a result, an advisory committee recommended that LANSCE scientists and their collaborators complete work in progress. At LANSCE, neutrons are produced by spallation when a pulsed, 800-MeV proton beam impinges on a tungsten target. The proton pulses are provided by the Clinton P. Anderson Meson Physics Facility (LAMPF) accelerator and a associated Proton Storage Ring (PSR), which can Iter the intensity, time structure, and repetition rate of the pulses. The LAMPF protons of Line D are shared between the LANSCE target and the Weapons Neutron Research (WNR) facility, which results in LANSCE spectrometers being available to external users for unclassified research about 80% of each annual LAMPF run cycle. Measurements of interest to the Los Alamos National Laboratory (LANL) may also be performed and may occupy up to an additional 20% of the available beam time. These experiments are reviewed by an internal program advisory committee. This year, a total of 127 proposals were submitted. The proposed experiments involved 229 scientists, 57 of whom visited LANSCE to participate in measurements. In addition, 3 (nuclear physics) participating research teams, comprising 44 scientists, carried out experiments at LANSCE. Instrument beam time was again oversubscribed, with 552 total days requested an 473 available for allocation.

  13. Biomimetic synthesis of selenium nanospheres by bacterial strain JS-11 and its role as a biosensor for nanotoxicity assessment: a novel se-bioassay.

    Directory of Open Access Journals (Sweden)

    Sourabh Dwivedi

    Full Text Available Selenium nanoparticles (Se-NPs were synthesized by green technology using the bacterial isolate Pseudomonas aeruginosa strain JS-11. The bacteria exhibited significant tolerance to selenite (SeO3(2- up to 100 mM concentration with an EC50 value of 140 mM. The spent medium (culture supernatant contains the potential of reducing soluble and colorless SeO3(2- to insoluble red elemental selenium (Se(0 at 37°C. Characterization of red Se° product by use of UV-Vis spectroscopy, X-ray diffraction (XRD, atomic force microscopy (AFM and transmission electron microscopy (TEM with energy dispersive X-ray spectrum (EDX analysis revealed the presence of stable, predominantly monodispersed and spherical selenium nanoparticles (Se-NPs of an average size of 21 nm. Most likely, the metabolite phenazine-1-carboxylic acid (PCA released by strain JS-11 in culture supernatant along with the known redox agents like NADH and NADH dependent reductases are responsible for biomimetic reduction of SeO3(2- to Se° nanospheres. Based on the bioreduction of a colorless solution of SeO3(2- to elemental red Se(0, a high throughput colorimetric bioassay (Se-Assay was developed for parallel detection and quantification of nanoparticles (NPs cytotoxicity in a 96 well format. Thus, it has been concluded that the reducing power of the culture supernatant of strain JS-11 could be effectively exploited for developing a simple and environmental friendly method of Se-NPs synthesis. The results elucidated that the red colored Se° nanospheres may serve as a biosensor for nanotoxicity assessment, contemplating the inhibition of SeO3(2- bioreduction process in NPs treated bacterial cell culture supernatant, as a toxicity end point.

  14. Exopolysaccharides from co-cultures of Weissella confusa 11GU-1 and Propionibacterium freudenreichii JS15 act synergistically on wheat dough and bread texture.

    Science.gov (United States)

    Tinzl-Malang, Saskia Katharina; Rast, Peter; Grattepanche, Franck; Sych, Janice; Lacroix, Christophe

    2015-12-02

    The storage of bread is limited by both physical (staling) and microbial (mainly fungal) spoilage. Exopolysaccharides (EPS) produced by lactic acid bacteria (LAB) and organic acids from propionibacteria (PAB) have been used to enhance texture and extend shelf-life of bakery products. In this study the functionality of EPS of Weissella confusa A3/2-1 (dextran), W. confusa F3/2-2 (dextran and levan), W. confusa 11GU-1 (dextran and ropy capsular polysaccharide) was evaluated in wheat bread. Two strains of Propionibacterium freudenreichii (Pf), shown to produce a heteropolysaccharide (Pf JS15) or a β-glucan (Pf DF30), were tested in single and mixed cultures with W. confusa (Wc). The EPS fermentates were prepared by batch fermentation of cereal- or malt-based medium using sucrose (Wc) or lactic acid (Pf) as carbon source. Incorporation of EPS from single culture fermentates and 1:1 Weissella-Propionibacterium fermentate mixtures revealed strong positive effects of dextran and ropy capsular polysaccharide produced by Wc 11GU-1 on bread staling retardation, with synergistic effects of EPS mixture from Wc 11GU-1 and Pf JS15. A co-fermentation of Wc 11GU-1 and Pf JS15 was developed to produce EPS together with antifungal organic acid mixture (acetate and propionate) in a single step process. The addition of 15% (w/w flour base) co-culture, yielding EPS, acetate and propionate concentrations of 1.5, 0.5 and 1g/kg dough, respectively, resulted in improved bread texture, increased loaf volume and decreased crumb firming during storage for 3days compared with control breads and breads supplemented with equivalent levels of chemical organic acids. Our data showed that EPS could compensate for the negative effects of chemical acetate and propionate in a concentration range exerting antifungal effects. The natural bioingredient produced by Wc 11GU-1 and Pf JS15 has potential for applications as antifungal, texture-building and anti-staling agent in breads, consistent with

  15. Crystallization and preliminary X-ray crystallographic analysis of polyphenol oxidase from Juglans regia (jrPPO1).

    Science.gov (United States)

    Zekiri, Florime; Bijelic, Aleksandar; Molitor, Christian; Rompel, Annette

    2014-06-01

    Tyrosinase is a type 3 copper enzyme that catalyzes the ortho-hydroxylation of monophenols to diphenols as well as their subsequent oxidation to quinones, which are precursors for the biosynthesis of melanins. The first plant tyrosinase from walnut leaves (Juglans regia) was purified to homogeneity and crystallized. During the purification, two forms of the enzyme differing only in their C-termini [jrPPO1(Asp101-Pro444) and jrPPO1(Asp101-Arg445)] were obtained. The most abundant form jrPPO1(Asp101-Arg445), as described in Zekiri et al. [Phytochemistry (2014), 101, 5-15], was crystallized, resulting in crystals that belonged to space group C121, with unit-cell parameters a=115.56, b=91.90, c=86.87 Å, α=90, β=130.186, γ=90°, and diffracted to 2.39 Å resolution. Crystals were only obtained from solutions containing at least 30% polyethylene glycol 5000 monomethyl ether in a close-to-neutral pH range.

  16. Red, Rough, Fast, and Perturbed: New Horizons Observations of KBO (15810) 1994 JR1 from the Kuiper Belt

    CERN Document Server

    Porter, Simon B; Benecchi, Susan; Verbiscer, Anne; Zangari, Amanda M; Weaver, H A; Lauer, Tod R; Parker, Alex H; Buie, Marc W; Cheng, Andrew F; Young, Leslie A; Olkin, Cathy B; Ennico, Kimberly; Stern, S Alan

    2016-01-01

    The 3:2 resonant KBO (15810) 1994 JR1 was observed by NASA's New Horizons spacecraft on November 2, 2015 from a distance of 1.85 AU, and again on April 7, 2016 from a distance of 0.71 AU. Acquired using the LOng Range Reconnaissance Imager (LORRI), these were the first close observations of any KBO other than Pluto, and the first ever of a small KBO. Combining ground-based and HST observations at small phase angles and the LORRI observations at higher phase angles, we produced the first disk-integrated solar phase curve of a typical KBO from alpha=0.6-58 degrees. Observations at these geometries, attainable only from a spacecraft in the outer Solar System, constrain surface properties such as macroscopic roughness and the single particle phase function. 1994 JR1 has a rough surface with a 37+/-5 degree mean topographic slope angle and has a relatively rapid rotation period of 5.47+/-0.33 hours. 1994 JR1 is currently 2.7 AU from Pluto; our astrometric points enable high-precision orbit determination and integr...

  17. Emil Godlewski, Jr. (1875-1944) pioneer of embryology at the Jagiellonian University of Krakow (Poland).

    Science.gov (United States)

    Sliwa, Leopold

    2008-01-01

    Emil Godlewski, Jr. (1875-1944) lived and worked in Krakow. He graduated from the Faculty of Medicine of the Jagiellonian University with the title of Doctor of Medical Science. He worked at the Faculty of Medicine, first in the Institute of Descriptive Anatomy and later as Professor of Biology and Embryology in the Department of Biology and Embryology, which he founded and led for many years. After early research on the development and histogenesis of muscles, professor Godlewski's scientific interests focused on regeneration and mechanisms regulating the process of fertilization, as well as early embryo development, blastulation and gastrulation. He was also interested in the origin of the primary differentiating cells in regenerates. He postulated the importance of epithelial tissue in this process and was the first to point out the change in the function, organization and role of the cells under the influence of external stimuli. Investigating fertilization and early development, he focused on the cooperation between the nucleus and the cytoplasm in the regulation of the early stages of development. Godlewski was also the author of the theory of migration of the inherited substances from the nucleus to the cytoplasm and, after their processing, from the cytoplasm to the nucleus. His works were never fragmentary, but always synthetical attempts at explaining important issues relating to the mechanisms of development. In 1936 Professor Godlewski was awarded the title of Member of the Pontifica Accademia delle Scienze. Apart from doing research and teaching, Emil Godlewski devoted a lot of time to social issues, especially those connected to medicine. When Poland regained independence after World War I, he actively participated in the reopening of the Jagiellonian University.

  18. Node .js Efficient Distributed Real-time Applications%N ode .j s高效分布式实时应用研究

    Institute of Scientific and Technical Information of China (English)

    刘生建; 罗林; 杜剑

    2014-01-01

    Node .js应用平台的出现,为大数据实时应用提供了一个很好的可选技术方案。研究了分布式实时应用处理中任务的抢占式处理策略和双路由策略,并探讨了在Node .js平台上利用Redis或ZeroM Q技术实现高效可靠分布式实时应用的方法。%Node .js application platform provides good optional technical solution for the real‐time applications of large da‐ta .This paper analyses preemptive processing strategy and dual routing strategy of task in the distributed real‐time pro‐cessing application ,and discuss the method to realize high efficient and reliable distributed real‐time applications using Re‐dis or ZeroM Q technologies on Node .js platform .

  19. Biosensor for direct determination of fenitrothion and EPN using recombinant Pseudomonas putida JS444 with surface-expressed organophosphorous hydrolase. 2. Modified carbon paste electrode.

    Science.gov (United States)

    Lei, Yu; Mulchandani, Priti; Chen, Wilfred; Mulchandani, Ashok

    2007-03-01

    A whole cell-based amperometric biosensor for highly selective, sensitive, rapid, and cost-effective determination of the organophosphate pesticides fenitrothion and ethyl p-nitrophenol thio-benzene phosphonate (EPN) is discussed. The biosensor comprised genetically engineered p-nitrophenol (PNP)-degrading bacteria Pseudomonas putida JS444 anchoring and displaying organophosphorous hydrolase (OPH) on its cell surface as biological sensing element and carbon paste electrode as the amperometric transducer. Surface-expressed OPH catalyzed the hydrolysis of organophosphorous pesticides such as fenitrothion and EPN to release PNP and 3-methyl-4- nitrophenol, respectively, which were subsequently degraded by the enzymatic machinery of P. putida JS444 through electrochemically active intermediates to the TCA cycle. The electro-oxidization current of the intermediates was measured and correlated to the concentration of organophosphates. Operating at optimum conditions, 0.086 mg dry wt of cell operating at 600 mV of applied potential (vs Ag/AgCl reference) in 50 mM citrate phosphate buffer, pH 7.5, with 50 muM CoCl2 at room temperature, the biosensor measured as low as 1.4 ppb of fenitrothion and 1.6 ppb of EPN. There was no interference from phenolic compounds, carbamate pesticides, triazine herbicides, or organophosphate pesticides without nitrophenyl substituent. The service life of the biosensor and the applicability to lake water were also demonstrated.

  20. Node.js and Mongodb-based Online Learning Test System Design%基于Node.js及Mongodb的在线学习测试系统设计

    Institute of Scientific and Technical Information of China (English)

    沈昕

    2015-01-01

    随着网络信息技术的发展,传统的本地学习测试技术已越来越难以满足用户远程学习测试和多用户大并发同时在线学习测试的需要,文章通过运用当前大并发数据处理最主流的Node.js+Mongodb的技术设计了一套支持多用户同时操作且具有大并发数据处理的在线学习测试系统,在满足用户需求的同时可以有效降低系统成本,并且提升用户的学习测试效率。%With the development of network information technology, the traditional local learning testing technology is more and more dififcult to meet user remote learning test and multi users concurrentonline at the same time, need to study and test, through the use of the current large concurrent data processing most mainstream Node.js+Mongodb technology to design a set of supporting multiple users simultaneous operation and has online large concurrent data processing the testing system of learning, to meet the needs of users at the same time can effectively reduce the system cost, andimprove the learning efifciency of test users.

  1. A two-component monooxygenase catalyzes both the hydroxylation of p-nitrophenol and the oxidative release of nitrite from 4-nitrocatechol in Bacillus sphaericus JS905.

    Science.gov (United States)

    Kadiyala, V; Spain, J C

    1998-07-01

    Bacteria that metabolize p-nitrophenol (PNP) oxidize the substrate to 3-ketoadipic acid via either hydroquinone or 1,2,4-trihydroxybenzene (THB); however, initial steps in the pathway for PNP biodegradation via THB are unclear. The product of initial hydroxylation of PNP could be either 4-nitrocatechol or 4-nitroresorcinol. Here we describe the complete pathway for aerobic PNP degradation by Bacillus sphaericus JS905 that was isolated by selective enrichment from an agricultural soil in India. Washed cells of PNP-grown JS905 released nitrite in stoichiometric amounts from PNP and 4-nitrocatechol. Experiments with extracts obtained from PNP-grown cells revealed that the initial reaction is a hydroxylation of PNP to yield 4-nitrocatechol. 4-Nitrocatechol is subsequently oxidized to THB with the concomitant removal of the nitro group as nitrite. The enzyme that catalyzed the two sequential monooxygenations of PNP was partially purified and separated into two components by anion-exchange chromatography and size exclusion chromatography. Both components were required for NADH-dependent oxidative release of nitrite from PNP or 4-nitrocatechol. One of the components was identified as a reductase based on its ability to catalyze the NAD(P)H-dependent reduction of 2,6-dichlorophenolindophenol and nitroblue tetrazolium. Nitrite release from either PNP or 4-nitrocatechol was inhibited by the flavoprotein inhibitor methimazole. Our results indicate that the two monooxygenations of PNP to THB are catalyzed by a single two-component enzyme system comprising a flavoprotein reductase and an oxygenase.

  2. A two-component monooxygenase catalyzes both the hydroxylation of p-nirophenol and the oxidative release of nitrite from 4-nitrocatechol in Bacillus sphaericus JS905

    Energy Technology Data Exchange (ETDEWEB)

    Kadiyala, V.; Spain, J.C. [Air Force Research Lab., Tyndall AFB, FL (United States)

    1998-07-01

    Bacteria that metabolize p-nitrophenol (PNP) oxidize the substrate to 3-ketoadipic acid via either hydroquinone or 1,2,4-trihydroxybenzene (THB); however, initial steps in the pathway for PNP biodegradation via THB are unclear. The product of initial hydroxylation of PNP could be either 4-nitrocatechol or 4-nitroresorcinol. Here the authors describe the complete pathway for aerobic PNP degradation by Bacillus sphaericus JS905 that was isolated by selective enrichment from an agricultural soil in India. Washed cells of PNP-grown JS905 released nitrite in stoichiometric amounts from PNP and 4-nitrocatechol. Experiments with extracts obtained from PNP-grown cells revealed that the initial reaction is a hydroxylation of PNP to yield 4-nitrocatechol. 4-nitrocatechol is subsequently oxidized to THB with the concomitant removal of the nitro group as nitrite. The enzyme that catalyzed the two sequential monooxygenations of PNP was partially purified and separated into two components by anion-exchange chromatography and size exclusion chromatography. Both components were required for NADH-dependent oxidative release of nitrite from PNP or 4-nitrocatechol. One of the components was identified as a reductase based on its ability to catalyze the NAD(P)H-dependent reduction of 2,6-dichlorophenolindophenol and nitroblue tetrazolium. Nitrite release from either PNP or 4-nitrocatechol was inhibited by the flavoprotein inhibitor methimazole. Their results indicate that the two monooxygenations of PNP to THB are catalyzed by a single two-component enzyme system comprising a flavoprotein reductase and an oxygenase.

  3. IG Statement: Arthur A. Elkins, Jr., on OIG report Early Warning Report: Main EPA Headquarters Warehouse in Landover, Maryland, Requires Immediate EPA Attention

    Science.gov (United States)

    Statement of Inspector General Arthur A. Elkins, Jr., on the Office of Inspector General (OIG) report Early Warning Report: Main EPA Headquarters Warehouse in Landover, Maryland, Requires Immediate EPA Attention.

  4. North American Regional Security: A Trilateral Framework. By Richard J. Kilroy, Jr., Abelardo Rodriquez Sumano, and Todd S. Hataley, Boulder, CO: Lynne Rienner Press, 2013.

    Directory of Open Access Journals (Sweden)

    Robert Stewart-Ingersoll

    2014-04-01

    Full Text Available North American Regional Security: A Trilateral Framework. By Richard J. Kilroy, Jr., Abelardo Rodriquez Sumano, and Todd S. Hataley, Boulder, CO: Lynne Rienner Press, 2013. ISBN 978-1-58826-854-9.

  5. ВИКОРИСТАННЯ ПЛАТФОРМИ NODE.JS ДЛЯ РОЗРОБКИ СУЧАСНИХ ВЕБ-СЕРВІСІВ

    OpenAIRE

    Остапенко, Сергій Олександрович; Прищепа, Татьяна Алексеевна

    2016-01-01

    Usage of Node.js platform for web-application development             Node.js - platform for developing high-load server-side web applications. Synchronous and asynchronous input - output model. Advantages of using technology for developing multi-user applications. Common mistakes in the use of Node.js.  Huge growth in popularity of technology.

  6. HST observations of the nebula around the central compact object in the Vela Jr. supernova remnant

    Science.gov (United States)

    Mignani, R. P.; de Luca, A.; Pellizzoni, A.

    2009-12-01

    Context: A handful of young (a few thousand years) supernova remnants (SNRs) host point-like X-ray sources, dubbed central compact objects (CCOs), which are thought to be radio-silent isolated neutron stars formed by the supernova explosion. So far, no CCO has been firmly detected at other wavelengths. However, ground-based observation in the Hα band detected a nebula around CXO J085201.4-461753, the CCO in the Vela Jr. SNR. The nebula has also been detected in deep R-band observations performed with the Very Large Telescope (VLT). Interestingly, both its extension and its flux in the R band are consistent with those measured in Hα, suggesting that the nebula spectrum is dominated by line emission, possibly produced by a velocity-driven bow-shock in the interstellar medium (ISM) or by its photo-ionisation from the neutron star. Aims: The aim of this work is to resolve the morphology of the Hα nebula around the CCO to verify the proposed interpretations. Methods: We performed high-resolution imaging observations of the nebula with the Wide Field Planetary Camera 2 (WFPC2) of the Hubble Space Telescope (HST) through the 656N filter, almost exactly centred on the rest wavelength of the Hα line. Results: Surprisingly enough, we did not detect the nebula in our WFPC2 image down to a 3 σ flux limit of ~3 × 10-15 erg cm-2 s-1. This limit is a factor of 10 fainter than the nebula flux measured in the discovery ground-based observations which were, however, performed with redder and broader Hα filters. Conclusions: The non-detection of the nebula in the narrower and bluer WFPC2 656N filter suggests that the peak of the emission might actually be at longer wavelengths. One possibility, compatible with the bow-shock scenario only, is that the Hα line is red-shifted by ~10-60 Å due to the neutron star motion with a radial velocity 450 ⪉ Vr ⪉ 2700 km s-1. The other possibility is that the nebula is a knot of [NII] emission (λ = 6583.6 Å) unrelated to CXO J085201

  7. BioJS: an open source standard for biological visualisation – its status in 2014 [v1; ref status: indexed, http://f1000r.es/2yy

    Directory of Open Access Journals (Sweden)

    Manuel Corpas

    2014-02-01

    Full Text Available BioJS is a community-based standard and repository of functional components to represent biological information on the web. The development of BioJS has been prompted by the growing need for bioinformatics visualisation tools to be easily shared, reused and discovered. Its modular architecture makes it easy for users to find a specific functionality without needing to know how it has been built, while components can be extended or created for implementing new functionality. The BioJS community of developers currently provides a range of functionality that is open access and freely available. A registry has been set up that categorises and provides installation instructions and testing facilities at http://www.ebi.ac.uk/tools/biojs/. The source code for all components is available for ready use at https://github.com/biojs/biojs.

  8. Oliver Wendell Holmes Jr. y su obra: Una fusión sistemático-existencial

    OpenAIRE

    Portela Valentín, Orlando Guillermo

    2016-01-01

    607 p. La presente Tesis, analiza las ideas filosófico-jurídicas del Juez Oliver Wendell Holmes, Jr. Y la manera en que dichas ideas influyen en las diferentes escuelas modernas del pensamiento jurídico norteamericano. En particular se analiza su visión instrumental del Derecho y la forma en que éste se relaciona con la moral, la historia y el poder político y económico, todas estas ideas que marcan el pensamiento filosófico-jurídico norteamericano en la modernidad.Para alcanzar este propó...

  9. Comparative assessment of cyclic J-R curve determination by different methods in a pressure vessel steel

    Science.gov (United States)

    Chowdhury, Tamshuk; Sivaprasad, S.; Bar, H. N.; Tarafder, S.; Bandyopadhyay, N. R.

    2016-04-01

    Cyclic J-R behaviour of a reactor pressure vessel steel using different methods available in literature has been examined to identify the best suitable method for cyclic fracture problems. Crack opening point was determined by moving average method. The η factor was experimentally determined for cyclic loading conditions and found to be similar to that of ASTM value. Analyses showed that adopting a procedure analogous to the ASTM standard for monotonic fracture is reasonable for cyclic fracture problems, and makes the comparison to monotonic fracture results straightforward.

  10. A novel marine bacterium Isoptericola sp. JS-C42 with the ability to saccharifying the plant biomasses for the aid in cellulosic ethanol production.

    Science.gov (United States)

    Santhi, Velayudhan Satheeja; Gupta, Ashutosh; Saranya, Somasundaram; Jebakumar, Solomon Robinson David

    2014-06-01

    The ever growing demands for food products such as starch and sugar produces; there is a need to find the sources for saccharification for cellulosic bioethanol production. This study provides the first evidence of the lignocellulolytic and saccharifying ability of a marine bacterium namely Isoptericola sp. JS-C42, a Gram positive actinobacterium with the cocci cells embedded on mycelia isolated from the Arabian Sea, India. It exhibited highest filter paper unit effect, endoglucanase, exoglucanase, cellobiohydrolase, β-glucosidase, xylanase and ligninase effect. The hydrolytic potential of the enzymes displayed the efficient saccharification capability of steam pretreated biomass. It was also found to degrade the paddy, sorghum, Acacia mangium and Ficus religiosa into simple reducing sugars by its efficient lignocellulose enzyme complex with limited consumption of sugars. Production of ethanol was also achieved with the Saccharomyces cerevisiae. Overall, it offers a great potential for the cellulosic ethanol production in an economically reliable and eco-friendly point-of-care.

  11. 浅析Node.js中的内存控制机制%A Brief Analysis of Memory Control Mechanisms for Node.js

    Institute of Scientific and Technical Information of China (English)

    李彦广; 赵科研

    2015-01-01

    在V8平台上构建Node.js,用户在使用过程中要通过JavaScricot进行调用的情况下,对Node.js在内存的管理进行分析介绍,在V8平台上的对内存的分配和回收机制进行了分析,提出了在使用单个Node.js进程的下,如何合理高效使用计算机的内存资源.经过测试仿真,方法是高效的.

  12. biojs-io-biom, a BioJS component for handling data in Biological Observation Matrix (BIOM format [version 2; referees: 1 approved, 2 approved with reservations

    Directory of Open Access Journals (Sweden)

    Markus J. Ankenbrand

    2017-01-01

    Full Text Available The Biological Observation Matrix (BIOM format is widely used to store data from high-throughput studies. It aims at increasing interoperability of bioinformatic tools that process this data. However, due to multiple versions and implementation details, working with this format can be tricky. Currently, libraries in Python, R and Perl are available, whilst such for JavaScript are lacking. Here, we present a BioJS component for parsing BIOM data in all format versions. It supports import, modification, and export via a unified interface. This module aims to facilitate the development of web applications that use BIOM data. Finally, we demonstrate its usefulness by two applications that already use this component. Availability: https://github.com/molbiodiv/biojs-io-biom, https://dx.doi.org/10.5281/zenodo.218277

  13. Flex-rigid pleuroscopic biopsy with the SB knife Jr is a novel technique for diagnosis of malignant or benign fibrothorax.

    Science.gov (United States)

    Wang, Xiao-Bo; Yin, Yan; Miao, Yuan; Eberhardt, Ralf; Hou, Gang; Herth, Felix J; Kang, Jian

    2016-11-01

    Diagnosing pleural effusion is challenging, especially in patients with malignant or benign fibrothorax, which is difficult to sample using standard flexible forceps (SFF) via flex-rigid pleuroscopy. An adequate sample is crucial for the differential diagnosis of malignant fibrothorax (malignant pleural mesothelioma, metastatic lung carcinoma, etc.) from benign fibrothorax (benign asbestos pleural disease, tuberculous pleuritis, etc.). Novel biopsy techniques are required in flex-rigid pleuroscopy to improve the sample size and quality. The SB knife Jr, which is a scissor forceps that uses a mono-pole high frequency, was developed to allow convenient and accurate resection of larger lesions during endoscopic dissection (ESD). Herein, we report two patients with fibrothorax who underwent a pleural biopsy using an SB knife Jr to investigate the potential use of this tool in flex-rigid pleuroscopy when pleural lesions are difficult to biopsy via SFF. The biopsies were successful, with sufficient size and quality for definitive diagnosis. We also successfully performed adhesiolysis with the SB knife Jr in one case, and adequate biopsies were conducted. No complications were observed. Electrosurgical biopsy with the SB knife Jr during flex-rigid pleuroscopy allowed us to obtain adequate samples for the diagnosis of malignant versus benign fibrothorax, which is usually not possible with SFF. The SB knife Jr also demonstrated a potential use for pleuropulmonary adhesions.

  14. Flex-rigid pleuroscopic biopsy with the SB knife Jr is a novel technique for diagnosis of malignant or benign fibrothorax

    Science.gov (United States)

    Wang, Xiao-Bo; Yin, Yan; Miao, Yuan; Herth, Felix J.; Kang, Jian

    2016-01-01

    Diagnosing pleural effusion is challenging, especially in patients with malignant or benign fibrothorax, which is difficult to sample using standard flexible forceps (SFF) via flex-rigid pleuroscopy. An adequate sample is crucial for the differential diagnosis of malignant fibrothorax (malignant pleural mesothelioma, metastatic lung carcinoma, etc.) from benign fibrothorax (benign asbestos pleural disease, tuberculous pleuritis, etc.). Novel biopsy techniques are required in flex-rigid pleuroscopy to improve the sample size and quality. The SB knife Jr, which is a scissor forceps that uses a mono-pole high frequency, was developed to allow convenient and accurate resection of larger lesions during endoscopic dissection (ESD). Herein, we report two patients with fibrothorax who underwent a pleural biopsy using an SB knife Jr to investigate the potential use of this tool in flex-rigid pleuroscopy when pleural lesions are difficult to biopsy via SFF. The biopsies were successful, with sufficient size and quality for definitive diagnosis. We also successfully performed adhesiolysis with the SB knife Jr in one case, and adequate biopsies were conducted. No complications were observed. Electrosurgical biopsy with the SB knife Jr during flex-rigid pleuroscopy allowed us to obtain adequate samples for the diagnosis of malignant versus benign fibrothorax, which is usually not possible with SFF. The SB knife Jr also demonstrated a potential use for pleuropulmonary adhesions. PMID:28066660

  15. JR6, a new compound isolated from Justicia procumbens, induces apoptosis in human bladder cancer EJ cells through caspase-dependent pathway.

    Science.gov (United States)

    He, Xiao-Li; Zhang, Peng; Dong, Xian-Zhe; Yang, Mei-Hua; Chen, Shi-Lin; Bi, Ming-Gang

    2012-11-21

    Numerous efforts have been conducted in searching for effective agents against cancer, in particular from herbal medicines. Justicia procumbens is a traditional herbal remedy which was produced in the south-western and southern provinces of China and Taiwan province used to treat fever, pain, and cancer. Here, we identified a new compound 6'-hydroxy justicidin A (JR6) from Justicia procumbens, which showed obvious anti-cancer effects. The cytotoxicity activity was assayed using MTT and SRB. Intracellular ROS visualization and quantification were acquired by using a laser scanning confocal microscopy. Apoptosis was measured using a propidium iodide (PI) apoptosis detection kit by flow cytometry. Activation of caspases (caspase-3, caspase-8, and caspase-9) was evaluated respectively using GloMax luminescence detector and Caspase-Glo 3,8,9 assay kits. Loss of mitochondrial membrane potential was observed by microscopy using JC-1 dye. Quantitative real-time PCR analysis was employed to detect the expression of protein associated with cell death. JR6 remarkably inhibited growth in human bladder cancer EJ cells by decreasing cell proliferation, reduced the SOD activity, increased the content of reactive oxygen species (ROS), and induced apoptosis. Activation of caspase-8, caspase-9, and the subsequent activation of caspase-3 indicated that JR6 may be inducing intrinsic and extrinsic apoptosis pathways. Caspase-3, caspase-8, and caspase-9 inhibition rendered this extract ineffective, thus JR6-induced apoptosis is caspase-dependent. JR6 also disrupted the mitochondrial membrane potential (Δψm) and unregulated the Bax and p53 expressions in EJ cells. These observations suggest that JR6 induce apoptosis through caspase-dependent pathway in human bladder cancer EJ cells, emphasizing the importance of this traditional medicine and thus presents a potential novel alternative to bladder cancer therapy. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  16. Biological properties of bacteriophages and biocontrol ofstaphylococcus aureus in foods%JS25噬菌体生物特性及对食品中致病菌的生物防治

    Institute of Scientific and Technical Information of China (English)

    龙门; 詹歌; 金双潮; 周卉; 杜庆飞; 王冉

    2016-01-01

    该试验以JS25噬菌体为研究对象,在分析稳定性的基础上,确定其对宿主细胞的侵染时间及最佳感染复数,最后通过在即食食品中的抑菌效应确定对即食食品的生物防治效果。结果表明,JS25噬菌体最佳感染复数为0.1、侵染时间为20 min、最适温度及pH值分别为4~60℃和6~9;另外,JS25噬菌体的潜伏期为20 min,60 min后平均裂解量为24.55 PFU/cell;试验结果表明,JS25噬菌体在即食食品中有较高的稳定性,且随噬菌体初始效价的增加,对即食食品中金黄色葡萄球菌的抑制作用也逐渐增加;但是在不同即食食品中的生物防治效果存在差异,主要表现为当效价为108及1010 PFU/g时,能分别有效的抑制鲜牛奶和圆白菜在贮藏过程中的金黄色葡萄球菌数量,当效价大于109 PFU/g时,对肉干及火腿中的致病菌有良好的防治效果。%Staphylococcus aureus, as one of the most common food-borne pathogens, is related to the health, safety in the food industry and fields of medicine and it can be transmitted to humans and animals through the food. Although many foods can serve as vehicles,Staphylococcus aureus is often isolated from ready-to-eat (RTE) foods, such as milk ,ham and cabbage. RTE foods have been implicated in most of the major listeriosis outbreaks in the last 30 years. Of particular concern is the fact that they are consumed directly, without a final bactericidal processing step. Since the preservation methods applicable to minimally processed RTE foods often seem to be insufficient to preventStaphylococcus aureus contamination and growth, new strategies to combat this opportunistic pathogen in foods are needed. Bacteriophages are natural enemies of bacterias and are suitable candidates for the environmentally friendly biocontrol of these pathogens. Using bacteriophages as a tool to the control of pathogens is a complementary to antibiotic therapy. We have isolated a

  17. Evaluation of DSA effects on SA516-Gr. 70 steel for reactor coolant piping elbow material. (Dynamic and quasi-static J-R curve characteristics.)

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Bong Sang; Hong, Jun Hwa; Yoon, Ji Hyun; Oh, Jong Myung; Kim, Jin Won [Korea Atomic Energy Reserach Institute, Taejon (Korea, Republic of)

    1997-11-01

    Dynamic and quasi-static J-R curve tests for RCS piping elbow material (SA516-Gr.70) were performed by DCPD method at various temperatures (25 deg C - 316 deg C). The objective of this project was to qualify that DSA would not affect the design safety margin for LBB analysis in the normal operating temperature region. This report describes the effects of temperature and loading rate on J-R characteristics of SA516-Gr. 70 steel for reactor coolant piping elbow material. 13 refs., 3 tabs., 9 figs. (author)

  18. Contributions in the Preparation and Processing of Composite Material Type Silumin 3 - Reinforced Matrix with S235JR Steel Mesh

    Directory of Open Access Journals (Sweden)

    Remus Belu-Nica

    2015-07-01

    Full Text Available In the paper are presented concrete data on developing technological batches of metal composite material (MCM type Silumin 3-reinforced matrix with steel mesh S235JR, with the indicating of the parameter and of the distinct stages of work. The samples from prepared batches were cut along and across by water jet abrasive process and were subjected to a destructive testing program and microstructural examination, obtaining results in concordance with the desired quality. The abrasive material used for cut was GMA granite with the average mesh of 80, the particle size ranging between 150-300 µm, density 2300 kg/m3 and melting point 1240°C.

  19. Creation and covenant in a via media position: The example of J.J.P. Valeton Jr

    Directory of Open Access Journals (Sweden)

    Bob Becking

    2013-06-01

    Full Text Available The year 2012 marked the centenary of the death of the Utrecht Old Testament scholar J.J.P. Valeton Jr (1848–1912. He was a representative of the ‘via media’ approach of Dutch theology, which aimed at joining critical scholarship and piety, by avoiding the pitfalls of modernism as well as orthodoxy. Valeton accepted the critical analysis of Graf, Kuenen, and Wellhausen, but meanwhile remained a pious person. This article will discuss Valeton’s contributions to critical scholarship of Genesis 1–3 as well as his profound ideas on ‘covenant’ as an expression of ‘friendship’. Loader’s distinction between ‘knowledge open to faith’ and ‘knowledge open for scientific approach’ is very helpful in understanding the works and ideas of Valeton.

  20. The Microcosm within: An interview with William B. Miller, Jr., on the Extended Hologenome theory of evolution.

    Science.gov (United States)

    Hunt, Tam

    2015-01-01

    There is a singular unifying reality underlying every biologic interaction on our planet. In immunology, that which does not kill you makes you different. -William B. Miller, Jr. We are experiencing a revolution in our understanding of inner space on a par with our exponentially increasing understanding of outer space. In biology, we are learning that the genetic and epigenetic complexity within organisms is far deeper than suspected. This is a key theme in William B. Miller Jr.'s book, The Microcosm Within: Evolution and Extinction in the Hologenome. We are learning also that a focus on the human genome alone is misleading when it comes to who we really are as biological entities, and in terms of how we and other creatures have evolved. Rather than being defined by the human genome alone, we are instead defined by the "hologenome," the sum of the human genome and the far larger genetic endowment of the microbiome and symbiotic communities that reside within and around us. Miller is a medical doctor previously in private practice in Pennsylvania and Phoenix, Arizona. This book is his first foray into evolutionary theory. His book could have been titled "The Origin of Variation" because this is his primary focus. He accepts that natural selection plays a role in evolution, but he demotes this mechanism to a less important role than the Modern Synthesis suggests. His main gripe, however, concerns random variation. He argues that random variation is unable to explain the origin and evolution of biological forms that we see in the world around us and in the historical record. Miller suggests that, rather than random variation as the engine of novelty, there is a creative impulse at the heart of cellular life, and even at the level of the genetic aggregate, that generates novelty on a regular basis. I probe this assertion in the interview below. He also highlights the strong role of "exogenous genetic assault" in variation and in his immunological model of evolution.

  1. Isolation and identification of a bacterial strain JS018 capable of degrading several kinds of organophosphate pesticides%一株能高效降解几种有机磷农药的菌株JS018的鉴定

    Institute of Scientific and Technical Information of China (English)

    江玉姬; 邓优锦; 刘新锐; 谢宝贵; 胡方平; 辛伟

    2006-01-01

    从福建三明农药厂附近的土壤分离、筛选获得一株能够高效降解甲基1605、辛硫磷等有机磷农药的菌株JS018,在LB培养基中发酵36h,对甲基1605、辛硫磷、三唑磷、敌敌畏的降解率分别为96%、99%、98.9%和69.0% .该菌在LB平板培养基上形成的菌落为粉红色,圆形,有光泽;经电镜观察,为小球状菌,直径0.5μm~0.75μm;革兰氏染色为阴性;能够在30℃~38℃温度范围内和pH7.0~9.0范围内很好的生长,最适生长温度为32℃,最适pH7.5~8.0;在含有6%NaCl以上的培养基中,不能生长.抗生素敏感性实验表明:JS018菌对安比西林、青霉素、林肯霉素有抗性;对卡那霉素、四环素、庆大霉素等敏感.碳源发酵实验表明:该菌株能发酵葡萄糖、海藻糖、松三糖、乙醇;不能发酵阿拉伯糖、蔗糖、甘露糖、木糖、果糖、半乳糖、麦芽糖、乳糖等;不能利用棕檬酸盐,不能液化明胶,不产生硫化氢,能还原硝酸盐,不产生吲哚,接触酶阳性,脲酶阳性.根据其形态特征,生理生化特性、16S rDNA序列分析,初步鉴定JS018为Roseomonas(玟瑰单胞菌属).

  2. 漾濞大泡核桃病程相关蛋白10基因JsPR10-1的克隆与表达分析

    Institute of Scientific and Technical Information of China (English)

    何华; 陈朝银; 韩青; 张南南; 葛锋; 刘迪秋

    2014-01-01

    病程相关蛋白(pathogenesisrelated protein, PR) 10的激活与积累在植物抗逆境胁迫中有非常重要的作用。根据漾濞大泡核桃(Juglans sigillata)编码PR10的EST(expressed sequence tag)序列设计引物,利用快速扩增cDNA末端技术,克隆得到PR10基因的全长cDNA序列,并命名为JsPR10-1。JsPR10-1全长cDNA为776 bp,含有483 bp的开放阅读框、74 bp 5′-非编码区以及219 bp 3′-非编码区,编码含有160个氨基酸的蛋白质。全长基因序列中含有1个124 bp的内含子。JsPR10-1编码的蛋白质与栎树(Quercus suber)、欧洲山毛榉(Fagus sylvatica)以及欧洲板栗(Castanea sativa)的PR10相似性较高,并且在PR10的系统进化树中与双子叶植物聚为一支。qRT-PCR分析结果表明,植物信号分子水杨酸、茉莉酸、乙烯以及过氧化氢处理均可诱导JsPR10-1表达。在接种胶孢炭疽菌(Colletotrichum gloeosporioides)后,JsPR10-1的表达量迅速上升并在接种8 h时达到最大值,表明JsPR10-1参与漾濞大泡核桃对胶孢炭疽菌的防卫反应。本研究为揭示漾濞大泡核桃抗性机制奠定了理论依据。

  3. Development of Matching System Based on Node .js%基于 Node .j s的撮合系统开发

    Institute of Scientific and Technical Information of China (English)

    刘生建; 袁冠远; 杨艳

    2014-01-01

    利用十分普及的移动智能手机和新兴的互联网应用开发技术,帮助人们随时随地发出具有明确时间和地域特征的具体需求,同时帮助商家及时获取交易机会。具备时效限制的撮合系统,依靠现代技术 Node .js、Socket .IO、MongoDB等实现。虽然采用这些新技术带来一定的学习曲线,但从整体上却能缩短项目开发周期,提升系统性能,同时也带来了开发思想的转变。%Intelligent mobile phone and new ly emerging internet application development technology can help people to is-sue needs from their smartphone with specific time and geographical characteristics whenever and wherever they want , businesses can access to these trading opportunities .The time demand matching system rely on modern technology inclu-ding Node .js ,Socket .IO ,MongoDB .Using new techniques may bring certain learning curve ,in the long run ,it can shorten the project development cycle ,improve system performance ,and bring changes in development thinking .

  4. 基于NodeJS平台搭建REST风格Web服务%Build a REST-style Web Services Platform Based Node JS

    Institute of Scientific and Technical Information of China (English)

    黄扬子

    2015-01-01

    Nodejs now can be said to be one of the hottest technology,it is a server-side JavaScript execution environment, the goal is to help programmers to build high scalability,can handle tens of thousands of concurrent requests of applications.Due to its compact and lfexible characteristics,it is suitable for used to construct a restful web service especially.This paper focuses on how the Web service based on the NodeJS platform architecture REST style.%NodeJS如今可谓是最火热的技术之一,是一个服务器端的JavaScript执行环境,目标是帮助程序员构建高度可伸缩性,能够处理数万条并发请求的应用程序。由于其小巧灵活的特点,特别适合用构建REST风格的Web服务。文章重点阐述如何基于NodeJS平台搭建REST风格的Web服务。

  5. 基于Node.JS内存缓存的Web服务性能研究%Web Service Performance Study Based on Node.JS In-memory Cache

    Institute of Scientific and Technical Information of China (English)

    高飞; 何利力; 高金标

    2015-01-01

    当前Node.JS在Web服务方面得到了广泛的关注和应用,Node.JS采用了一个称为“事件循环(event loop)”的架构,可以快捷地编写出可扩展性高的服务器,也显著提高了服务器的性能。Node.JS选择了一种既能提高性能,又能减低开发复杂度的架构,这是一个非常重要的特性。主要研究了Node.JS的内存机制和缓存策略及其工作的原理,并对内存缓存的进行测试和提出了几种性能优化策略,进而说明其在Web服务上的优越性。%This paper mainly studies the Node.JS memory mechanism and caching strategy and its working principle,and tests of the in-memory cache and puts forward several performance optimization strategy,and shows its superiority in a Web service.

  6. JavaScript Concurrent Flow-Control Framework Based on Node.js%基于Node.js的JavaScript并发控制流框架

    Institute of Scientific and Technical Information of China (English)

    李轶

    2015-01-01

    Because of the asynchronous characteristic of I/O ,Node.js is quite suitable for developing server-side JavaScript applications. To implement concurrent asynchronous I/O control ,developers have to write tedious code manually ,it becomes a barrier to developers. Based on the concurrent counter ,a concurrent flow-control framework can be constructed. The framework achieved concurrent control between multiple asynchronous I/O in a direct viewing way. Thus ,it benefits server-side JavaScript developments and also promotes the efficiency of development.%Node.js因其异步I/O的特性,非常适合于服务器端的JavaScript开发。然而为实现此环境下异步I/O的并发控制,开发者不得不手工编写繁琐的代码,因而给开发者造成了障碍。以并发计数器为基础,可以设计一个并发控制流框架。该框架以直观的调用形式,实现了异步I/O间的并发控制;其不仅有助于Node.js环境下的JavaScript开发,更提高了开发者的开发效率。

  7. A novel marine bacterium Isoptericola sp. JS-C42 with the ability to saccharifying the plant biomasses for the aid in cellulosic ethanol production

    Directory of Open Access Journals (Sweden)

    Velayudhan Satheeja Santhi

    2014-06-01

    Full Text Available The ever growing demands for food products such as starch and sugar produces; there is a need to find the sources for saccharification for cellulosic bioethanol production. This study provides the first evidence of the lignocellulolytic and saccharifying ability of a marine bacterium namely Isoptericola sp. JS-C42, a Gram positive actinobacterium with the cocci cells embedded on mycelia isolated from the Arabian Sea, India. It exhibited highest filter paper unit effect, endoglucanase, exoglucanase, cellobiohydrolase, β-glucosidase, xylanase and ligninase effect. The hydrolytic potential of the enzymes displayed the efficient saccharification capability of steam pretreated biomass. It was also found to degrade the paddy, sorghum, Acacia mangium and Ficus religiosa into simple reducing sugars by its efficient lignocellulose enzyme complex with limited consumption of sugars. Production of ethanol was also achieved with the Saccharomyces cerevisiae. Overall, it offers a great potential for the cellulosic ethanol production in an economically reliable and eco-friendly point-of-care.

  8. "Dienas ritms - pozitīvu emociju veicinātājs pirmsskolā 2-3 gadus veciem bērniem"

    OpenAIRE

    Deņisova, Ilze

    2016-01-01

    Kvalifikācijas darba tēma: Dienas ritms - pozitīvu emociju veicinātājs pirmsskolā 2 - 3 gadus veciem bērniem. Pētījuma mērķis: Izpētīt 2 - 3 gadus vecu bērna pozitīvu emociju veicināšanas iespējas dienas ritmā. Darba sastāv no 3 nodaļām un 11 apakšnodaļām. Darbā veikts pētījums par pozitīvo emociju veicināšanu dienas ritmā 2 – 3 gadus veciem bērniem. Analizēta literatūra par emociju nozīmi bērna attīstībā, atspoguļojot dažādas emocijas, par pētījuma metožu izvēli un raksturojumu, kā arī apkop...

  9. 20 Poemas para ler no bonde. Fotografias de Horacio Coppola. Translated by Fabrício Corsaletti e Samuel Titan Jr

    Directory of Open Access Journals (Sweden)

    Ellen Cristina Nascimento Lopes

    2017-05-01

    Full Text Available Review of GIRONDO, Oliverio. 20 Poemas para ler no bonde. Fotografias de Horacio Coppola; tradução de Fabrício Corsaletti e Samuel Titan Jr. São Paulo: Editora 34, 2014; 112 p. (Coleção Fábula.

  10. Peer-Reviewed Research and the IEP: Implications of "Ridley School District v. M.R. and J.R. ex rel. E.R." (2012)

    Science.gov (United States)

    Yell, Mitchell L.; Katsiyannis, Antonis; Losinski, Mickey; Marshall, Kelsey

    2016-01-01

    This article examines a case out of the U.S. Court of Appeals for the Third Circuit: "Ridley School District v. M.R and J.R. ex rel. E.R." (2012). The case is the first circuit court case in which the Individuals with Disabilities Education Improvement Act requirement that special education services be based on peer-reviewed research…

  11. Peer-Reviewed Research and the IEP: Implications of "Ridley School District v. M.R. and J.R. ex rel. E.R." (2012)

    Science.gov (United States)

    Yell, Mitchell L.; Katsiyannis, Antonis; Losinski, Mickey; Marshall, Kelsey

    2016-01-01

    This article examines a case out of the U.S. Court of Appeals for the Third Circuit: "Ridley School District v. M.R and J.R. ex rel. E.R." (2012). The case is the first circuit court case in which the Individuals with Disabilities Education Improvement Act requirement that special education services be based on peer-reviewed research…

  12. The Mutable Prophet: Dr. Martin Luther King, Jr., and the Echo Chamber Campaign of "U. S. News & World Report," 1964-1968.

    Science.gov (United States)

    Lentz, Richard

    Between 1964 and 1968, "U. S. News and World Report" engaged in symbolic discourse with its readership through its coverage of Dr. Martin Luther King, Jr. "U. S. News" faced a dilemma in the mingling of King's force as a symbol with the power exerted by the egalitarian principles that Gunnar Myrdal identified as components of…

  13. The Academy on the Firing Line: William F. Buckley, Jr.'s "God and Man at Yale" and the Modern Conservative Critique of Higher Education

    Science.gov (United States)

    Laukaitis, John J.

    2013-01-01

    In 1951, William F. Buckley, Jr. was a recent alumnus of Yale University and former editor of the "Yale Daily News" when his first major work, "God and Man at Yale: The Superstitions of 'Academic Freedom'," became a controversial polemic that attracted national attention. In his work, Buckley claimed Yale's faculty advanced…

  14. Arthur Schlesinger, Jr.'s "Middle Way out of Vietnam: The Limits of Technocratic Realism" as the Basis for Foreign Policy Dissent.

    Science.gov (United States)

    Depoe, Stephen P.

    1988-01-01

    Analyzes Arthur Schlesinger, Jr.'s dissenting position on Vietnam by considering it as representative of the mode of foreign policy argument called "technocratic realism." Argues that such dissent can offer only an incomplete critique of U.S. foreign policy, because it does not question the policy's underlying purposes. (SR)

  15. Extraction and Structure Analysis of the Nematicidal Active Substances Produced by Bacillus amyloliquefaciens JK-JS3%解淀粉芽孢杆菌JK-JS3杀线活性物质的分离与结构分析

    Institute of Scientific and Technical Information of China (English)

    朱丽梅; 吴小芹; 胡飞杰; 徐浩

    2011-01-01

    Bacillus amyloliquefaciens JK-JS3, isolated from the leaf of the Pinus massoniana in Dr. Sun Yat-sen' s mausoleum, is a bacterium and has high nematicidal activity to a nematode(Bursaphelenchus xylophilus). A water solution with the nematicidal activity was isolated and purified from the bacterium culture medium by acid and alkali sedimentation method, and the components was analyzed by gas chromatography and mass spectrum. The result showed that the nematicidal activity components was composed of three compounds which included Hexahydro-5-methyI-l-phenyl-l ,3,5-triazine-2-thione, 2,2-dimethyl-N-phenylpropanethioamide and Semiarbazide,4-( 1,7,7-trimethylbicyclo[2. 2. 1 Jheptyl-2-ideno)-. The three compounds have not been reported to have the nematicidal activity before based on a search of information and patents of the three chemical compounds in the SciFinder.%利用酸碱沉淀法分离提纯解淀粉芽孢杆菌JK-JS3分泌的杀线活性物质,获得具有杀线活性的水溶液,通过气质联用方法对其化合物的结构进行分析和鉴定,从该杀线组合物中共鉴定出3种化合物,分别为5 -甲基-1 -苯基-6H -1,3,5-三嗪-2-硫酮、2,2-二甲基-N-苯丙硫代酰胺和樟脑醛缩氨脲.对3种化合物在SciFinder数据库中进行专利和文献检索,未检索到上述化合物具有杀松材线虫活性的报道.

  16. FeatureViewer, a BioJS component for visualization of position-based annotations in protein sequences [v1; ref status: indexed, http://f1000r.es/2u2

    Directory of Open Access Journals (Sweden)

    Leyla Garcia

    2014-02-01

    Full Text Available Summary: FeatureViewer is a BioJS component that lays out, maps, orients, and renders position-based annotations for protein sequences. This component is highly flexible and customizable, allowing the presentation of annotations by rows, all centered, or distributed in non-overlapping tracks. It uses either lines or shapes for sites and rectangles for regions. The result is a powerful visualization tool that can be easily integrated into web applications as well as documents as it provides an export-to-image functionality. Availability: https://github.com/biojs/biojs/blob/master/src/main/javascript/Biojs.FeatureViewer.js; http://dx.doi.org/10.5281/zenodo.7719

  17. Inläsning av match- och dragningsinformation med användning av node.js : Ett arbete utfört vid företaget Svenska spel

    OpenAIRE

    Olsson, Rasmus; Ramadanovic, Alen

    2013-01-01

    Detta examensarbete har genomförts hos det statliga spelföretaget Svenska Spel i Sundbyberg. Svenska Spel har övervägt att använda sig av en ny plattform, Node.js, för att utveckla sina läsmoduler som läser match- och dragningsinformation. Idag används läsmoduler implementerade i programmeringsspråken C# och C för detta ändamål. Svenska Spel vill nu ha en utvärdering av hur lämpligt det är för dem att använda Node.js implementerade läsmoduler. Målet med detta examensarbete har varit att under...

  18. BioJS DAGViewer: A reusable JavaScript component for displaying directed graphs [v1; ref status: indexed, http://f1000r.es/2ut

    Directory of Open Access Journals (Sweden)

    Alexis Kalderimis

    2014-02-01

    Full Text Available Summary: The DAGViewer BioJS component is a reusable JavaScript component made available as part of the BioJS project and intended to be used to display graphs of structured data, with a particular emphasis on Directed Acyclic Graphs (DAGs. It enables users to embed representations of graphs of data, such as ontologies or phylogenetic trees, in hyper-text documents (HTML. This component is generic, since it is capable (given the appropriate configuration of displaying any kind of data that is organised as a graph. The features of this component which are useful for examining and filtering large and complex graphs are described. Availability: http://github.com/alexkalderimis/dag-viewer-biojs; http://github.com/biojs/biojs; http://dx.doi.org/10.5281/zenodo.8303.

  19. Eagle Pass Jr. High Seismology Team: Strategies for Engaging Middle School "At-Risk" Students in Authentic Research

    Science.gov (United States)

    Brunt, M. R.; Ellins, K. K.; Frohlich, C. A.

    2011-12-01

    In 2008, during my participation in the NSF-sponsored Texas Earth & Space Science (TXESS) Revolution professional development program, I was awarded an AS-1 seismograph through IRIS's Seismographs in Schools Program. This program serves to create an international educational seismic network that allows teachers across the country and around the world to share seismic data in real-time using online tools, classroom activities, and technical support documents for seismic instruments. Soon after receiving my AS-1, I founded and began sponsoring the Eagle Pass Jr. High Seismology Team which consists of selected 7th and 8th grade students. Eagle Pass Jr. High is a Title 1 school that serves a predominantly "at-risk" Hispanic population. We meet after school once a week to learn about earthquakes, seismic waves, analyze recorded seismic event data using computer software programming, and correspond with other students from schools around the country. This team approach has been well received by fellow TXESS Revolution teachers with AS-1 seismographs and will be implemented by David Boyd, STEM coordinator for Williams Preparatory Academy in Dallas, Texas this fall 2011. All earthquakes recorded by our seismograph station (EPTX), which has remained online and actively recording seismic data since 2008, are catalogued and then plotted on a large world map displayed on my classroom wall. A real-time seismogram image updates every five minutes and along with all earthquakes recorded since installation can be viewed on our webpage http://www.iris.edu/hq/ssn/schools/view/eptx. During the 2010-2011 school year, my seismology team and I participated in an earthquake research study led by Dr. Cliff Frohlich at the Institute for Geophysics. The study examined seismograms and felt reports for the 25 April 2010 Alice, Texas, earthquake, in order to investigate its possible connection to oil and gas production in the Stratton oil and gas field. A research paper detailing our findings

  20. Confirmation of mutant alpha 1 Na,K-ATPase gene and transcript in Dahl salt-sensitive/JR rats.

    Science.gov (United States)

    Ruiz-Opazo, N; Barany, F; Hirayama, K; Herrera, V L

    1994-09-01

    As the sole renal Na,K-ATPase isozyme, the alpha 1 Na,K-ATPase accounts for all active transport of Na+ throughout the nephron. This role in renal Na+ reabsorption and the primacy of the kidney in hypertension pathogenesis make it a logical candidate gene for salt-sensitive genetic hypertension. An adenine (A)1079-->thymine (T) transversion, resulting in the substitution of glutamine276 with leucine and associated with decreased net 86Rb+ (K+) influx, was identified in Dahl salt-sensitive/JR rat kidney alpha 1 Na,K-ATPase cDNA. However, because a Taq polymerase chain reaction amplification-based reanalysis did not detect the mutant T1079 but rather only the wild-type A1079 alpha 1 Na,K-ATPase allele in Dahl salt-sensitive rat genomic DNA, we reexamined alpha 1 Na,K-ATPase sequences using Taq polymerase error-independent amplification-based analyses of genomic DNA (by polymerase allele-specific amplification and ligase chain reaction analysis) and kidney RNA (by mRNA-specific thermostable reverse transcriptase-polymerase chain reaction analysis). We also performed modified 3' mismatched correction analysis of genomic DNA using an exonuclease-positive thermostable DNA polymerase. All the confirmatory test results were concordant, confirming the A1079-->T transversion in the Dahl salt-sensitive alpha 1 Na,K-ATPase allele and its transcript, as well as the wild-type A1079 sequence in the Dahl salt-resistant alpha 1 Na,K-ATPase allele and its transcript. Documentation of a consistent Taq polymerase error that selectively substituted A at T1079 (sense strand) was obtained from Taq polymerase chain reaction amplification and subsequent cycle sequencing of reconfirmed known Dahl salt-sensitive/JR rat mutant T1079 alpha 1 cDNA M13 subclones. This Taq polymerase error results in the reversion of mutant sequence back to the wild-type alpha 1 Na,K-ATPase sequence. This identifies a site- and nucleotide-specific Taq polymerase misincorporation, suggesting that a structural

  1. Desenvolvimento pós-embrionário do intestino anterior de Dermatobia hominis (Linnaeus Jr. (Diptera, Cuterebridae Post-embryonic development of Dermatobia hominis (Linnaeus Jr. (Diptera, Cuterebridae foregut

    Directory of Open Access Journals (Sweden)

    Ana Maria Vieira

    2001-03-01

    Full Text Available Foregut in D. hominis (Linnaeus Jr., 1781 as the majority of the larval Diptera somatic tissue, is made up of polytenic cells, and grows at the expenses of the polytenization of its nuclei followed by the increase in size of each cell. The oesophagus, of ectodermic origem, is interiorly covered by a chitinous squamous epithelium that rests upon a very thin basal lamina. This sheet is surrounded by thick muscle bundles. The oesophagus intussuscepts the midgut forming the cardia. The cardia, with three epithelial layers: two internal ones, of ectodermal origin and one external of endodermic origin. At the anterior portion of the cardia, between these two types of epithelium, there is a cluster of small, non polytenic cells, forming the imaginal disk of the foregut. Metamoiphosis begins at the end of the larval period with signs of nuclear degeneration of all the polytenic cells, as well as the increase in number of the imaginal disk ones. The oesophagic portion intussuscepted into the cardia, everts; its cells suffer apoptosis and are replaced by the new cells growing from the imaginal disk. The external layer cells also degenerate and are pinched off into the lumen of the very anterior portion of the midgut. The newly formed oesophagus intussuscepts "de novo" to form the two internal layers of the adult cardia. At the same time the midgut regenerative cells grow anteriorly to form the new external layer of the adult cardia.

  2. In Silico Approach to Support that p-Nitrophenol Monooxygenase from Arthrobacter sp. Strain JS443 Catalyzes the Initial Two Sequential Monooxygenations.

    Science.gov (United States)

    Kallubai, Monika; Amineni, Umamaheswari; Mallavarapu, Megharaj; Kadiyala, Venkateswarlu

    2015-06-01

    p-Nitrophenol (PNP), used primarily for manufacturing pesticides and dyes, has been recognized as a priority environmental pollutant. It is therefore important to reduce the input of this toxicant into the environment and to establish approaches for its removal from the contaminated sites. PNP monooxygenase, a novel enzyme from Gram-positive bacteria like Arthrobacter sp. and Bacillus sp., that comprises two components, a flavoprotein reductase and an oxygenase, catalyzes the initial two sequential monooxygenations to convert PNP to trihydroxybenzene. Accurate and reliable prediction of this enzyme-substrate interactions and binding affinity are of vital importance in understanding these catalytic mechanisms of the two sequential reactions. As crystal structure of the enzyme has not yet been published, we built a homology model for PNP monooxygenase using crystallized chlorophenol 4-monooxygenase from Burkholderia cepacia AC1100 (3HWC) as the template. The model was assessed for its reliability using PROCHECK, ERRAT and ProSA. Molecular docking of the physiological substrates, PNP and 4-nitrocatechol (4-NC), was carried out using Glide v5.7 implemented in Maestro v9.2, and the binding energies were calculated to substantiate the prediction. Docking complexes formed by molecular level interactions of PNP monooxygenase-PNP/4-NC without or with the cofactors, FAD and NADH, showed good correlation with the established experimental evidence that the two-component PNP monooxygenase catalyzes both the hydroxylation of PNP and the oxidative release of nitrite from 4-NC in B. sphaericus JS905. Furthermore, molecular dynamics simulations performed for docking complexes using Desmond v3.0 showed stable nature of the interactions as well.

  3. Effect of molybdenum on wear resistance of Cr-Nb hard-faced S355JR steel

    Energy Technology Data Exchange (ETDEWEB)

    Thongchitrugsa, Nut; Chianpairot, Amnuaysak; Hartung, Fritz; Lothongkum, Gobboon [Chulalongkorn Univ., Bangkok (Thailand). Dept. of Metallurgical Engineering

    2014-03-01

    The effect of Mo on the abrasive wear resistance of (20-23)Cr-(7-8)Nb hard-faced S355JR steel by shielded metal arc welding (SMAW) was studied. Four types of flux, consisting of fixed Cr and Nb but varying Mo contents, coated on hard-facing electrode were used. Microstructure, micro hardness, and abrasive wear resistance of the hard-faced surface were investigated by ASTM G65 D procedure. The original microstructures consist of the primary coarse and eutectic carbides. Mo affects morphology of carbides by decreasing primary carbide size. When Mo content in the hard-faced surface was up to 6.43 wt.-%, the highest abrasive wear resistance and micro hardness were obtained. The decrease of primary carbide size is attributed to the increased nucleation induced by Mo addition. Network structure was observed when the Mo content reaches 10.19 wt.-%. The main mechanisms of wear are micro-cutting and carbide pulling out. (orig.)

  4. On the Expansion Rate, Age, and Distance of the Supernova Remnant G266.2-1.2 (Vela Jr.)

    CERN Document Server

    Allen, G E; DeLaney, T; Filipovic, M D; Houck, J C; Pannuti, T G; Stage, M D

    2014-01-01

    An analysis of Chandra ACIS data for two relatively bright and narrow portions of the northwestern rim of G266.2-1.2 (a.k.a. RX J0852.0-4622 or Vela Jr.) reveal evidence of a radial displacement of 2.40 +/- 0.56 arcsec between 2003 and 2008. The corresponding expansion rate (0.42 +/- 0.10 arcsec/yr or 13.6 +/- 4.2%/kyr) is about half the rate reported for an analysis of XMM-Newton data from a similar, but not identical, portion of the rim over a similar, but not identical, time interval (0.84 +/- 0.23 arcsec/yr, Katsuda et al. 2008a). If the Chandra rate is representative of the remnant as a whole, then the results of a hydrodynamic analysis suggest that G266.2-1.2 is between 2.4 and 5.1 kyr old if it is expanding into a uniform ambient medium (whether or not it was produced by a Type Ia or Type II event). If the remnant is expanding into the material shed by a steady stellar wind, then the age could be as much as 50% higher. The Chandra expansion rate and a requirement that the shock speed be greater than or...

  5. From Catheters To Ventricular Assist Devices: 60 Years of Cardiovascular Experiences With William L. Winters, JR., M.D.

    Science.gov (United States)

    Winters, W L

    2015-01-01

    Automatic typewriters, transistor radios, microfiche, black and white television…while considered high-tech in the 1950s, these technologies seem limited when viewed from the 21st century. The same is true for cardiovascular medicine, which back then relied on electrocardiograms and X-rays for most diagnoses. In the 60 years since, advances in medical capabilities have progressed at a staggering pace. Patient research that once required months poring over paper charts is now reduced to hours using electronic medical record databases. Diagnostic images that once took days to process can now be accessed instantly through ultrasound and magnetic resonance imaging. While a half-century ago no one would have imagined accessing any and all information with a 5-second Google search, so too would noninvasive heart surgery been considered unimaginable. Since the 1950s when he graduated from medical school, William L. Winters, Jr., has been a first-hand witness to breathtaking innovations in cardiovascular medicine-both globally and in Houston. Author of Houston Hearts: A History of Cardiovascular Surgery and Medicine at Houston Methodist DeBakey Heart & Vascular Center and long-time medical editor of the Methodist DeBakey Cardiovascular Journal, Dr. Winters sat down with the journal editors this past April to share his insights from the last half-century of medical practice.

  6. Martin Luther King纪念园方案分析%Analysis of Martin Luther King Jr.National Memorial

    Institute of Scientific and Technical Information of China (English)

    王欣; 王瑛

    2005-01-01

    马丁·路德·金(Martin Luther King Jr.)纪念园是美国国家林荫绿地内的在建纪念物.介绍了该纪念物的设计竞赛过程和获选作品ROWA设计组方案的构思及特点,结合美国国家林荫绿地纪念景观风格和纪念景观设计风尚之流变等设计背景,从延续文脉、时间和空间的融合、材料人文含义的运用和塑造场所精神4个方面分析方案设计手法,并进一步归纳美国现代纪念园的设计特点,讨论对我国纪念园设计的启发意义,探索我国现代园林设计借鉴世界先进文化的道路.图2参11

  7. Distributed Data Stream Log Service System Built with Node.js%一种使用Node.js构建的分布式数据流日志服务系统

    Institute of Scientific and Technical Information of China (English)

    张煜

    2013-01-01

    This paper introduces a distributed log service System treating logs as data streams built with Node.js. and provides a solution to the problem that with the service number increases, the operation based on files gives rise to disadvantages that files I/O have performance bottleneck and have to be checked at multiple places. Logs are considered as a sort of data stream rather than files. Write a new log service system named octoLogStreamlet which collects the streams to a central storage with Node.js. Combining Node.js’ non-blocking I/O model and outstanding performance of NoSQL database, the system meets the requirements to cope with distributed data streams. The system is suitable for computer clusters needing centralized storage of logs, which provides great convenience for processing and utilizing logs.%  介绍了使用 Node.js 来实现一个分布式的数据流日志处理系统.为解决随着运行服务数量的增加,基于文件的日志操作会带来的存储性能瓶颈和必须要多处查看等问题提供一种方案.将日志从文件还原为流,利用Node.js 来实现一个可分布式获得各日志数据流并且汇聚到中心存储的新型日志系统 octoLogStreamlet.充分利用Node.js 的非阻塞 I/O 特性及 NoSQL 数据库的读写高性能,实现多个数据流同时写入.系统适用于有集中存放日志需求的计算机服务集群.集中存放后对日志的处理和使用均提供了极大的便利.

  8. Optimising JS visualisation for notebooks

    CERN Document Server

    She, Harry

    2017-01-01

    In a large number of notebooks that are created and used by users of CERN, many important components are those related to graphical visualization. These include, but are not limited to graphs and histograms of data and events from physical detectors. However, the information used to display the ROOT graphical primitives is too comprehensive and hence cause the physical space requirements of the notebooks to grow drastically as the number of graphs and plots increases. Analysis has been performed to trim out redundant information from the notebooks, as well as providing insight into browsing ROOT objects within a notebook.

  9. Winter Use Plans Final Environmental Impact Statement Summary for the Yellowstone and Grand Teton National Parks and John D. Rockefeller, Jr., Memorial Parkway

    OpenAIRE

    United States, Department of the Interior, National Park Service

    2000-01-01

    This document presents and analyzes seven alternatives for winter use management in Yellowstone National Park (YNP), Grand Teton National Park (GTNP), and the John D. Rockefeller, Jr., Memorial Parkway (the Parkway). YNP, encompassing 2.22 million acres, and GTNP, comprising 310,000 acres, form the core of the Greater Yellowstone Ecosystem, described as the last large, nearly intact ecosystem in the northern temperate zone. The approved plan will serve as a management plan for the three na...

  10. The First High-Phase Observations of a KBO: New Horizons Imaging of (15810) 1994 JR 1 from the Kuiper Belt

    Science.gov (United States)

    Porter, Simon; Spencer, John R.; Benecchi, Susan D.; Verbiscer, Anne J.; Zangari, Amanda Marie; Weaver, Harold A.; Lauer, Tod R.; Parker, Alex; Buie, Marc W.; Cheng, Andrew F.; Young, Leslie; Olkin, Catherine B.; Ennico, Kimberly; Stern, S. Alan; New Horizons Science Team

    2016-10-01

    (15810) 1994 JR1, a 3:2 resonant Kupier Belt Object (KBO), was observed by NASA's New Horizons spacecraft using the LOng Range Reconnaissance Imager (LORRI) on November 2, 2015 from a distance of 1.85 AU, and again on April 7, 2016 from a distance of 0.71 AU. These were the first close observations of any KBO other than Pluto, and the first ever of a small KBO at close range. Combining ground-based and HST observations at small phase angles and the LORRI observations at higher phase angles, we produced the first disk-integrated solar phase curve of a typical in-situ KBO from 0.6 to 58 degrees phase angle. Observations at these geometries, a range only attainable using a spacecraft in the outer Solar System, constrain surface properties such as macroscopic roughness and the single particle phase function. 1994 JR1 has a rough surface with a 37 +/- 5 degrees mean topographic slope angle and has a relatively rapid rotation period of 5.47 +/- 0.33 hours, with a lightcurve amplitude of 0.8 magnitudes from the spacecraft. 1994 JR1 is currently 2.7 AU from Pluto; our astrometric points enable high-precision orbit determination and integrations which show that it comes this close to Pluto every 2.4 million years (10,000 heliocentric orbits), causing Pluto to perturb 1994 JR1. During the November spacecraft observation, the KBO was simultaneously observed using the Hubble Space Telescope in two colors, confirming its very red spectral slope. These observations have laid the groundwork for numerous potential future distant KBO observations in the proposed New Horizons-Kuiper Belt Extended Mission.

  11. Análisis del efecto entalla en la tenacidad aparente y en los micromecanismos de rotura del acero S275JR en condiciones de lower shelf

    OpenAIRE

    Cicero González, Sergio; García Pemán, Tiberio; Madrazo Acebes, Virginia; Ruiz Martínez, Estela

    2014-01-01

    La resistencia a fractura de los materiales es generalmente mayor en condiciones entalladas que en condiciones fisuradas. En otras palabras, cuando el radio de entalla crece se produce igualmente un aumento de la tenacidad aparente a fractura, que es aquella observada en condiciones entalladas. Este artículo presenta un análisis del efecto entalla en el acero S275JR cuando opera a temperaturas pertenecientes al Lower Shelf del material, es decir, aquellas temperaturas en las cuales la fractur...

  12. PPI layouts: BioJS components for the display of Protein-Protein Interactions [v1; ref status: indexed, http://f1000r.es/2u5

    Directory of Open Access Journals (Sweden)

    Gustavo A. Salazar

    2014-02-01

    Full Text Available Summary: We present two web-based components for the display of Protein-Protein Interaction networks using different self-organizing layout methods: force-directed and circular. These components conform to the BioJS standard and can be rendered in an HTML5-compliant browser without the need for third-party plugins. We provide examples of interaction networks and how the components can be used to visualize them, and refer to a more complex tool that uses these components. Availability: http://github.com/biojs/biojs; http://dx.doi.org/10.5281/zenodo.7753

  13. Development of JS399-19·Tebuconazole 48% SC to Control Wheat Scab%48%氰烯菌酯·戊唑醇悬浮剂防治小麦赤霉病的开发

    Institute of Scientific and Technical Information of China (English)

    刁亚梅; 周明国; 王建新; 刘德如

    2012-01-01

    [目的]为了延缓刨制杀菌剂氰烯菌酯的抗药性和扩大氰烯菌酯的应用范围,通过室内活性筛选和田间试验等研究,开发了48%氰烯菌酯·戊唑醇悬浮剂.[结果]室内活性筛选表明:氰烯菌酯与戊唑醇复配在1~6∶1时对小麦赤霉病具有协同相加作用.2011年田间试验表明:48%氰烯菌酯·戊唑醇SC(氰烯菌酯36%+戊唑醇12%)对小麦赤霉病具有优良的防效,在推荐有效成分使用剂量300~420 g a.i./hm2下防效达63.8%~87.5%.[结论]该药剂除了防治小麦赤霉病,还可用于防治小麦白粉病、小麦纹枯病等麦类病害.%[Aims] In order to delay the resistance of JS399-19 against wheat scab and extend its application, new formulation, JS399-19- tebuconazole 48% SC, were developed by bioassay and field trail. [Results] Bioassay showed that the composition of JS399-19 and tebuconazole at ratios of 1-6:1 had synergisU'c effect against Fusarium graminearum in vitro. Field trail showed that this new SC had excellent effect to control wheat scab. The control effect were 63.8-87.5% at recommended dosage of 300-420 g a.i./ha. [Conclusions] The new formulation, JS399-19 · tebuconazole 48% SC, had been used to control wheat scab and other deseases, such as wheat powdery mildew, wheat sharp eyespot, etc.

  14. Application of multiplex PCR for the screening of genotyping system for the rare blood groups Fy(a-), s-, k-, Di (b-) and Js(b-)%多重PCR筛选广西壮族人群稀有血型Fy(a-)、s-、k-、Di(b-)、Js(b-)

    Institute of Scientific and Technical Information of China (English)

    焦伟; 谢莉; 黎海澜; 蓝娇; 莫柱宁; 阳子驥; 刘斐; 肖瑞平; 贺云蕾

    2014-01-01

    Objective To screen rare blood groups Fy(a-),s-,k-,Di(b-) and Js(b-) in an ethnic Zhuang population.Methods Sequence-specific primers were designed based on single nucleotide polymorphism (SNP) sites of blood group antigens Fyb and s.A specific multiplex PCR system Ⅰ was established.Multiplex PCR system Ⅱ was applied to detect alleles antigens Dib,k,Jsb1910 and Jsb2019 at the same time.The two systems was were used to screen for rare blood group antigens in 4490 randomly selected healthy donors of Guangxi Zhuang ethnic origin.Results We successfully made the multiplex PCR system Ⅰ.We detected the rare blood group antigens using the two PCR system.There are five Fy(a-),three s(-),two Di(b-) in 4490 Guangxi zhuang random samples.The multiplex PCR system Ⅰ has achieved good accuracy and stability.With multiplex PCR systems Ⅰ and Ⅱ,4490 samples were screened.Five Fy (a-),three s(-) and two Di(b-) samples were discovered.Conclusion Multiplex PCR is an effective methods,which can be used for high high-throughput screening of rare blood groups.The rare blood types of Guangxi Zhuang ethnic origin obtained through the screening can provide valuable information for compatible blood transfusion.Through screening we obtained precious rare blood type materials which can be used to improve the capability of compatible infusion and reduce the transfusion reactions.%目的 通过分子生物学方法,筛选广西壮族随机献血者样本中的Fy(a-)、s-、k-、Di(b-)、Js(b-)表型,获得壮族稀有血型资料,丰富中国稀有血型库.方法 基于血型抗原Fyb、s等位基因单核苷酸多态性位点,设计序列特异性引物,优化PCR条件,建立多重PCR体系Ⅰ;并使用筛选稀有血型等位基因Dib、k、Jsb1910、Jsb2019多重PCR体系Ⅱ共同对4490份广西壮族随机献血者样本进行筛选.结果 成功构建检测血型抗原Fyb、s的多重PCR体系Ⅰ,经验证多重PCR体系Ⅰ具有良好的准确度和稳定性.

  15. Auto-reflexão ou repetição: Bento Prado Jr. e a crítica ao recurso frankfurtiano à psicanálise Self-reflection or repetition: Bento Prado Jr. and the critique of psychoanalysis in Frankfurt School

    Directory of Open Access Journals (Sweden)

    Vladimir Safatle

    2004-12-01

    Full Text Available Procura-se analisar o projeto de uma filosofia da psicanálise desenvolvido por Bento Prado Jr. Trata-se de, por um lado, compreender o regime proposto de articulação entre filosofia e psicanálise e, por outro, a partir da posição do regime de articulação, avaliar a orientação da crítica de Bento Prado Jr. ao recurso frankfurtiano à psicanálise (Habermas e Marcuse principalmente e do elogio da leitura deleuzeana do conceito freudiano de pulsão de morte.This article aims to discuss the project of a philosophy of psychoanalysis developed by Bento Prado Jr. First, we need to understand the Bento Prado's way to articulate philosophy and psychoanalysis. After, the Bento Prado's critique of the use of psychoanalysis in Frankfurt School (Habermas and Marcuse and his eloge of deleuzean use of death drive will be evaluated.

  16. Disease: H00003 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Cannon GW, Jackson CG, Samuelson CO Jr, Ward JR, Williams HJ, Clegg DO. Chloramb... Wassom JS. Toxicological review of busulfan (Myleran). Mutat Res 168:15-45 (1986) PMID:3865372 (carcinogen)

  17. A expansão e a eficiência da escola rural em São Paulo: atuação e posicionamentos de Almeida Jr. a partir de estatísticas oficiais - The expansion and the efficiency of the rural school in São Paulo: the performance and the thinking of Almeida Jr. based o

    Directory of Open Access Journals (Sweden)

    Luciana Maria Viviani

    2011-07-01

    Full Text Available O objetivo deste estudo é analisar os discursos produzidos por Almeida Jr. sobre o ensino rural, entre as décadas de 1930 e 1940, e as formas sob as quais ele utilizou dados estatísticos para sustentar as suas opiniões e a sua atuação como administrador do ensino paulista. O estudo dessas questões pretende colaborar na ampliação do entendimento acerca das propostas para o ensino rural, tema bastante debatido nesse período. Por meio da análise de publicações oficiais paulistas e de artigos da Revista Brasileira de Estudos Pedagógicos, verificou-se que Almeida Jr., médico e educador ligado ao grupo dos chamados renovadores do ensino, defendia propostas voltadas para a qualidade do ensino e para a organização de uma escola básica comum, ainda que adaptada ao meio rural.Palavras-chave: educação rural, estatísticas educacionais, intelectuais da educação. THE EXPANSION AND THE EFFICIENCY OF THE RURAL SCHOOL IN SÃO PAULO: THE PERFORMANCE AND THE THINKING OF ALMEIDA JR. BASED ON OFFICIAL STATISTICSAbstractThe objective of this paper is to analyze de speeches made by Almeida Jr. about the rural education, between the decades of 1930 and 1940, and the way under which he used the statistics data to sustain his opinions and his performance as the manager of education in São Paulo. By analyzing the São Paulo’s official publications and the articles published in the Revista Brasileira de Estudos Pedagógicos, it has been found that Almeida Jr., a doctor and an educator connected to the group composed by some men who were called the renewers of education, sustained proposals which were bent to the good quality of education and to the organization of a unique elementary school, though to fit the country environment.Key-words: rural education, educational statistics, intellectuals in education. LA EXPANSIÓN Y LA EFICIENCIA DE LA ESCUELA RURAL EN SAN PABLO: ACTUACIÓN Y OPINIONES DE ALMEIDA JR. A PARTIR DE ESTAD

  18. PsicquicGraph, a BioJS component to visualize molecular interactions from PSICQUIC servers [v1; ref status: indexed, http://f1000r.es/2up

    Directory of Open Access Journals (Sweden)

    Jose M. Villaveces

    2014-02-01

    Full Text Available Summary: Protein interaction networks have become an essential tool in large-scale data analysis, integration, and the visualization of high-throughput data in the context of complex cellular networks. Many individual databases are available that provide information on binary interactions of proteins and small molecules. Community efforts such as PSICQUIC aim to unify and standardize information emanating from these public databases. Here we introduce PsicquicGraph, an open-source, web-based visualization component for molecular interactions from PSIQUIC services. Availability: PsicquicGraph is freely available at the BioJS Registry for download and enhancement. Instructions on how to use the tool are available here http://goo.gl/kDaIgZ and the source code can be found at http://github.com/biojs/biojs and DOI:10.5281/zenodo.7709.

  19. 一个基于 Ext-JS技术的污水管理信息平台的设计与实现%DESIGN AND IMPLEMENTATION OF AN EXT-JS TECHNOLOGY-BASED SEWAGE MANAGEMENT INFORMATION PLATFORM

    Institute of Scientific and Technical Information of China (English)

    卢冶; 徐明; 苏勇

    2013-01-01

    面对污水处理信息化发展趋势中诸如异构的网络环境、众多的组织机构、多样化的角色分工、特定的运行模式等亟须解决的问题,在Spring 和Hibernate 框架的基础上,采用B/S结构的多层架构设计思想,设计并实现一个基于 Ext-JS技术的污水管理信息平台。 Ext-JS良好的组件化设计提高了Web 界面品质和开发效率,数据同步模型则实现了水务数据的有机整合与共享,这些系统特点为水务管理工作进入新的层次奠定了基础。%Facing the problems to be solved urgently in the informatisation development trend of sewage treatment such as the heterogeneous network environments , great number of organisations , diversifying division of labour for roles , and specific running mode , etc., a sewage information management platform based on Ext-JS technology is designed and implemented , which is on the basis of Spring and Hibernate framework and adopts a multi-layer architecture design idea of B/S structure.Good component-based programming in Ext-JS improves the quality of Web pages and development efficiency .Water affairs data ’ s flexible integration and sharing are achieved by using data synchronisation model .Thereby all of these system features will lay the foundation for water affairs management upgrading to a new level .

  20. 基于NodeJS的智能家居语音控制系统服务器端设计与实现%Design of NodeJS-based Smart Home Voice-controI System Server

    Institute of Scientific and Technical Information of China (English)

    单振华; 王舒憬; 陈凯; 强杰

    2016-01-01

    This paper introduces the overaI structure, technicaI means and the achievement of the main function moduIes of the design of NodeJS-based smart home voice controI system server.The system is mainIy to achieve reaI-time server-side speech recognition.Through sending the received voice data to the Baidu cIoud recognition,the recognition resuIt is re-turned to the cIient.In addition,NodeJS owns the feature of the event-driven,the asynchronous programming,and its out-standing advantages make procedures to achieve high concurrency.%介绍了基于NodeJS的智能家居语音控制系统服务器端总体结构、技术手段和主要功能模块的实现。该系统服务器端主要实现实时语音识别,通过把接收的语音数据发送给百度语音云端识别,把识别结果返回给客户端。此外, NodeJS采用事件驱动、异步编程,其突出的优点使得程序能够实现高并发处理。NodeJS非阻塞模式的IO处理给NodeJS带来在相对低系统资源耗用下的高性能与出众的负载能力。

  1. AQWT-J S01型深井水处理系统在王庄煤矿的应用%Application on AQWT-JS0 1 deep well water treatment system in Wangzhuang Coal Mine

    Institute of Scientific and Technical Information of China (English)

    王辉锋; 任书堂

    2013-01-01

    介绍了煤矿液压支架乳化液用水要求及现状。根据王庄煤矿深井水特点,设计并采用了AQWT-JS01型深井水处理系统,该系统包括介质过滤、活性炭吸附以及反渗透系统。处理后水质达到配置液压支架系统乳化液用水要求,保证了液压支架系统正常工作并延长其使用寿命。进行了经济效益分析,结果表明该矿采用此设备后产生了良好的环境、社会和经济效益。%This paper introduces the emulsion water requirements and current situation of hydraulic support in Coal Mine.According to the characters of deep well water in Wangzhuang coal mine,AQWT-JS01 deep well water treatment system has been designed and implemented.This treatment system includes dielectric filter,activated carbon adsorption and reverse osmosis system.Treated water quality reached the emulsion water requirements of hydraulic support sysG tem,ensured the hydraulic support system work properly and extend service life.The economic benefits analysis have been conducted.The results showed that Wangzhuang Coal Mine have good environmental,social and economical benefits after using this system.The economic beneG fits was analyzed,and the results showed that the mine after using the system has a good enviG ronmental,social and economic benefits.

  2. PULSAR: A High-Repetition-Rate, High-Power, CE Phase-Locked Laser for the J.R. Macdonald Laboratory at Kansas State University

    Energy Technology Data Exchange (ETDEWEB)

    Ben-Itzhak, Itzik (Itzhak) [J.R. Macdonald Laboratory, Physics Department, Kansas State University; Carnes, Kevin D. [J.R. Macdonald Laboratory, Physics Department, Kansas State University; Cocke, C. Lew [J.R. Macdonald Laboratory, Physics Department, Kansas State University; Fehrenbach, Charles W. [J.R. Macdonald Laboratory, Physics Department, Kansas State University; Kumarappan, Vinod [PULSAR: A High-Repetition-Rate, High-Power, CE Phase-Locked Laser for the J.R. Macdonald Laboratory at Kansas State University; Rudenko, Artem [J.R. Macdonald Laboratory, Physics Department, Kansas State University; Trallero, Carlos [J.R. Macdonald Laboratory, Physics Department, Kansas State University

    2014-05-09

    This instrumentation grant funded the development and installation of a state-of-the-art laser system to be used for the DOE funded research at the J.R. Macdonald Laboratory at Kansas State University. Specifically, we purchased a laser based on the KMLABs Red-Dragon design, which has a high repetition rate of 10-20 kHz crucial for multi-parameter coincidence measurements conducted in our lab. This laser system is carrier-envelope phase (CEP) locked and provides pulses as short as 21 fs directly from the amplifier (see details below). In addition, we have developed a pulse compression setup that provides sub 5 fs pulses and a CEP tagging capability that allows for long measurements of CEP dependent processes.

  3. Caracterización molecular de InJR06, un integron de clase 1 situado en un plásmido conjugativo de Salmonella enterica ser. Typhimurium

    OpenAIRE

    Conza,José Di; Ayala, Juan Alfonso; Porto, Ayelén; Mollerach, Marta; Gutkind,Gabriel

    2005-01-01

    Se investigó la presencia de integrones de clase 1, 2 y 3 en cuatro aislamientos pediátricos de Salmonella enterica ser. Typhimurium (S. Typhimurium). Un integrón de clase 1 se detectó en una cepa de S. Typhimurium, la única que además presentaba resistencia a varios antibióticos aminoglucósidos. Este integrón, llamado InJR06, y los determinantes de resistencia a aminoglucósidos se localizaron en pS06, un plásmido conjugativo de tamaño grande (≥ 55 kb). El análisis de la región variable...

  4. Making lemonade from lemons: a case study on loss of space at the Dolph Briscoe, Jr. Library, University of Texas Health Science Center at San Antonio.

    Science.gov (United States)

    Tobia, Rajia C; Feldman, Jonquil D

    2010-01-01

    The setting for this case study is the Dolph Briscoe, Jr. Library, University of Texas Health Science Center at San Antonio, a health sciences campus with medical, dental, nursing, health professions, and graduate schools. During 2008-2009, major renovations to the library building were completed including office space for a faculty development department, multipurpose classrooms, a 24/7 study area, study rooms, library staff office space, and an information commons. The impetus for changes to the library building was the decreasing need to house collections in an increasingly electronic environment, the need for office space for other departments, and growth of the student body. About 40% of the library building was remodeled or repurposed, with a loss of approximately 25% of the library's original space. Campus administration proposed changes to the library building, and librarians worked with administration, architects, and construction managers to seek renovation solutions that meshed with the library's educational mission.

  5. The LVIS Jr. microstent to assist coil embolization of wide-neck intracranial aneurysms: clinical study to assess safety and efficacy

    Energy Technology Data Exchange (ETDEWEB)

    Moehlenbruch, M.; Herweh, C.; Behrens, L.; Jestaedt, L.; Bendszus, M.; Pham, M. [University of Heidelberg Medical Center, Department of Neuroradiology, Heidelberg (Germany); Amiri, H.; Ringleb, P.A. [University of Heidelberg Medical Center, Department of Neurology, Heidelberg (Germany)

    2014-05-15

    This study was aimed to assess clinical safety and efficacy of the LVIS Jr. microstent in stent-assisted coil embolization of wide-neck intracranial aneurysms. IRB approved single-center interventional clinical study in 22 patients (10 females, 12 males, mean age 55, age range 33-74 years) for the endovascular treatment of wide-neck aneurysms. After obtaining informed consent, patients were included according to the following criteria: aneurysm fundus-to-neck ratio < 2 or neck diameter > 4 mm, and a parent vessel diameter of ≤3.5 mm. Primary end point for clinical safety was absence of death, absence of major or minor stroke, and absence of transient ischemic attack. Primary end point for treatment efficacy was complete angiographic occlusion according to the Raymond-Roy Occlusion Classification (RROC) immediately after the procedure and at follow-up after 3 and 6 months on magnetic resonance imaging (MRI). In 20/22 (91 %) of patients, the primary end point of safety was reached; in the two remaining patients, transient ischemic attack, but no permanent deficit was observed; in 16/22 (73 %), efficient occlusion (RROC1) was reached, and in 6/22 (27 %), a residual neck remained (RROC2). Single [seven with antegrade, two in crossover configuration, and four with ''first-balloon-then-stent'' (FBTS) technique] or double-stent (eight patients with Y configuration and one patient with X configuration) deployment was technically successful in all cases. Deployment of the LVIS Jr. microstent in various single- or double-stent configurations is safe and effective to assist the treatment of intracranial wide-neck aneurysms. (orig.)

  6. Res Publica aukohus heidab juhtidele ette eetikavääratust / Toomas Mattson

    Index Scriptorium Estoniae

    Mattson, Toomas, 1970-

    2002-01-01

    Ilmunud ka: Põhjarannik ; Severnoje Poberezhje 22. november lk. 3;4. Res Publica aukohus arvab, et Res Publica juhid on rikkunud erakonna põhikirja, sisekorda ja eetikakoodeksit Kohtla-Järve juhtumi lahendamisel. Kohtla-Järvel sai linnapeaks riisumiskahtlusega uurimise all olev Valeri Korb tänu Keskerakonna ja Res Publica koalitsioonileppele. Kommenteerib Juhan Kivirähk

  7. Lääne firmad peavad Eesti radari pärast kohtulahingut / Toomas Mattson

    Index Scriptorium Estoniae

    Mattson, Toomas, 1970-

    2001-01-01

    Radarihankekonkursil osalenud Itaalia radaritootja Alenia Marconi Systems ja Prantsuse firma Thales vaidlustasid Tallinna halduskohtus valitsuse sajalase korralduse, mille alusel sõlmis kaitseministeerium radari ostmise lepingu USA firmaga Lockheed-Martin

  8. 137 miljoni kroonist kärbet saadab kiremöll / Toomas Mattson

    Index Scriptorium Estoniae

    Mattson, Toomas, 1970-

    2002-01-01

    Riigikogu reformib koalitsiooni tahtel tudengite protestidest hoolimata radikaalselt sotsiaalhoolekande seadust. Vt. samas art. "Opositsioon üritab arutelu venitada", milles Marju Lauristin nimetab seaduseelnõu jõhkraks

  9. Juhan Parts : oleme Isamaaliiduga lähedased / Juhan Parts ; interv. Toomas Mattson

    Index Scriptorium Estoniae

    Parts, Juhan, 1966-

    2003-01-01

    Peaminister Juhan Parts vastab küsimustele, mis puudutavad Isamaaliitu kui Res Publicale kõige lähedasemat võimalikku koalitsioonipartnerit, nn suure koalitsiooni tekkimise võimalust. Skeem: Jõujooned Riigikogus

  10. Illegaalne relvaäri on kui ämblikuvõrk / Toomas Sildam, Toomas Mattson

    Index Scriptorium Estoniae

    Sildam, Toomas, 1961-

    1995-01-01

    Venemaa süüdistused. Kaitseliit. Politsei. Ilmunud ka: Vetshernije Vesti, 13. nov. 1995, lk. 1; 14. nov. 1995, lk. 5; 16. nov. 1995, lk. 5; 18. nov. 1995, lk. 7; Pühapäevaleht, 11. nov. 1995, lk. 10-12; Molodjozh Estonii : Kupetsheskaja Gavan, 17. nov. 1995, lk. 8-9

  11. Res Publica aukohus heidab juhtidele ette eetikavääratust / Toomas Mattson

    Index Scriptorium Estoniae

    Mattson, Toomas, 1970-

    2002-01-01

    Ilmunud ka: Põhjarannik ; Severnoje Poberezhje 22. november lk. 3;4. Res Publica aukohus arvab, et Res Publica juhid on rikkunud erakonna põhikirja, sisekorda ja eetikakoodeksit Kohtla-Järve juhtumi lahendamisel. Kohtla-Järvel sai linnapeaks riisumiskahtlusega uurimise all olev Valeri Korb tänu Keskerakonna ja Res Publica koalitsioonileppele. Kommenteerib Juhan Kivirähk

  12. Juhan Parts : oleme Isamaaliiduga lähedased / Juhan Parts ; interv. Toomas Mattson

    Index Scriptorium Estoniae

    Parts, Juhan, 1966-

    2003-01-01

    Peaminister Juhan Parts vastab küsimustele, mis puudutavad Isamaaliitu kui Res Publicale kõige lähedasemat võimalikku koalitsioonipartnerit, nn suure koalitsiooni tekkimise võimalust. Skeem: Jõujooned Riigikogus

  13. Study of T L LiF: Mg,Ti (Model JR1152C) material for its use in the environmental monitoring; Estudio del material TL LiF: Mg, Ti (JR1152C) para su empleo en el monitoreo ambiental

    Energy Technology Data Exchange (ETDEWEB)

    Molina P, D.; Diaz B, E.; Prendes A, M. [Centro de Proteccion e Higiene de las Radiaciones, CPHR, Apdo. postal 6195, Habana 6, CP 10600, Ciudad Habana (Cuba)

    1999-07-01

    In order to evaluate the possibility to use the T L material of LiF: Mg,Ti (Model JR1152C) as environmental dosemeter it was realized its characterization of it according to the established criterion in the standard IEC-1066. The properties studied were: homogeneity of the lot, reproducibility, response linearity, detection threshold, auto irradiation, residual signal, response pride (fading) and angular dependence. The results prove the compliment of the IEC requirements and therefore the applicability of this dosemeter in the environmental monitoring. (Author)

  14. Examining a Proposed Job Retention Model for Adult Workers with Mental Retardation

    Science.gov (United States)

    Fornes, Sandra L.

    2008-01-01

    This research provides an analysis of factors predicting job retention (JR), job satisfaction (JS), and job performance (JP) of workers with mental retardation (MR). The findings highlight self-determination as a critical skill in influencing three important employee's outcomes, JR, JS, and JP. The intent of the study was to develop job retention…

  15. 漾濞大泡核桃病程相关蛋白10基因JsPR10-1的克隆与表达分析%Cloning and Expression Analysis of a Pathogenesis-related Protein 10 Gene from Juglans sigillata

    Institute of Scientific and Technical Information of China (English)

    何华; 陈朝银; 韩青; 张南南; 葛锋; 刘迪秋

    2014-01-01

    The activation and accumulation of pathogenesis-related protein (PR) 10 play predominant roles in the defense response against pathogens.Based on a Juglans sigillata expressed sequence tag (EST) encoding PR10,gene-specific primers were designed and used to amplify the full-length cDNA of a novel PR10 gene by rapid amplification of cDNA ends (RACE).This gene was named as JsPR10-1.JsPR10-1 was 776 bp in length with an open reading frame (ORF) of 483 bp,a 5'-untranslated region (UTR) of 74 bp,and a 3'-UTR of 219 bp,and the ORF encoded a protein with 160 amino acid residues.There was an intron of 124 bp in the genomic sequence of JsPR10-1.Homology analysis indicated that JsPR10-1 was homologous with PR10s from Quercus suber,Fagus sylvatica and Castanea sativa;moreover,JsPR10-1 clustered together with the PR10s from dicots in the phylogenetic tree.qRT-PCR analysis showed that the expression levels of JsPR10-1 were induced by four different plant signaling molecules,including salicylic acid,jasmonic acid,ethylene,and H2O2.In addition,after inoculation with Colletotrichum gloeosporioides,JsPR10-1 was sharply up-regulated with the highest expression level at 8 h.The JsPR10-1 gene was involved in the defense response against C.gloeosporioides.This experiment lays a theoretical foundation for revealing the mechanism of resistance in J.sigillata.%病程相关蛋白(pathogenesis-related protein,PR) 10的激活与积累在植物抗逆境胁迫中有非常重要的作用.根据漾濞大泡核桃(Juglans sigillata)编码PR10的EST (expressed sequence tag)序列设计引物,利用快速扩增cDNA末端技术,克隆得到PR10基因的全长cDNA序列,并命名为JsPR10-1.JsPR10-1全长cDNA为776 bp,含有483 bp的开放阅读框、74 bp 5'-非编码区以及219 bp 3'-非编码区,编码含有160个氨基酸的蛋白质.全长基因序列中含有1个124 bp的内含子.JsPR10-1编码的蛋白质与栎树(Quercus suber)、欧洲山毛榉(Fagus sylvatica

  16. MITOLOGIAS MIDIÁTICAS DE PELÉ, RONALDINHO GAÚCHO E NEYMAR JR. ANÁLISE SEMIÓTICO-DISCURSIVA DAS HQS DE MAURÍCIO DE SOUSA

    Directory of Open Access Journals (Sweden)

    Fábio de Carvalho Messa

    2015-08-01

    Full Text Available Este artigo apresenta e discute os perfis de três personagens-títulos das histórias em quadrinhos da Turma da Mônica, de Maurício de Sousa – Pelezinho, Ronaldinho Gaúcho e Neymar Jr., craques do futebol brasileiro – para evidenciar as diferentes formas de representação simbólica do futebol no imaginário midiático. A partir de um trabalho metodológico de monitoramento semiótico-discursivo das edições impressas de fevereiro de 2013 a fevereiro de 2014, selecionaramse algumas passagens para destacar as distintas nuances do conhecimento sobre o futebol veiculado nas narrativas, por meio de determinadas ocorrências sígnicas. São elas: características das personalidades dos heróis (sujeitos históricos e suas bases parafrásticas e paródicas; figuratividades do futebol – presença da bola, aspectos sociais e pedagógicos do desporto, propaganda ideológica, estereótipos e índices morais e políticos subjacentes às narrativas. Com base nessa categorização e nas teorias da linguagem de Roland Barthes e Umberto Eco, identificamos que a revista do Pelezinho, proposta mais antiga do autor, concentra no personagem grande parte do repertório cultural do futebol brasileiro dos anos 70-80, condensando questões de linguagem e comportamento, assim como a disseminação dos saberes sobre o futebol e sua pedagogia, incluindo seus desdobramentos afetivos e sociais. Já as histórias de Ronaldinho Gaúcho e Neymar Jr. têm suas propostas encomendadas a partir de temas recorrentes da agenda midiática nacional dos anos 2000, com um menor comprometimento com os saberes acerca do futebol. Por meio de enredos pouco problematizáveis, as políticas editoriais dessas duas últimas tematizam amenidades do universo infantil, engrenam campanhas ideológicas, que reforçam estereótipos e padrões morais, geralmente extraídos da factualidade  jornalística e/ou da mitologia midiático-esportiva brasileira.

  17. 基于Node.JS的远程实时虚拟康复训练系统研究%Research of a remote real-time virtual rehabilitation training system based on Node.JS

    Institute of Scientific and Technical Information of China (English)

    王清波; 虞成; 朱隽典; 胡志奇; 袁杰; 王琳斌

    2016-01-01

    Objective:To establish a remote real-time virtual rehabilitation training system by using vision feedback mechanism of virtual reality, help doctors to understand the status of patients in time and facilitate patients to receive doctors’ professional evaluation in the process of rehabilitation out of hospital.Methods: A remote real-time virtual rehabilitation training system was established by Node-JS and Socket.io. The part of server collected the bending angle of finger based on bending sensor and used the serial port to transmit data by blue-tooth, and then the wireless data glove was established. The server was established by Node.JS, using the module of node-serial port to receive serial data and the module of Socket.io to build remote real-time connection. The part of client used Mozilla Firefox browser with websocket support and the web for signing in the server to receive the remote data. The glove data was sent by module of jUART and was received by virtual hand module for virtual hand control.Results: A remote real-time data transmition system was established by Node.JS. It could transmit the bending data accurately to control the 3D virtual hand model under different geographical conditions.Conclusion: A remote real-time virtual rehabilitation training system based on Node.JS could help the hand’s rehabilitation of patients who were out of hospital without doctors’ face to face guidance.%目的:建立远程实时虚拟康复训练监控系统,利用虚拟现实的视觉等反馈机制,帮助医生及时了解患者现状并指导下一步康复,便于患者在离院康复过程中接收医生专业化评价。方法:通过Node.JS和Socket.io构建远程实时数据传输系统,服务器端采用弯曲传感器测量手指弯曲程度,利用串口通过蓝牙模块传输数据,从而构建无线数据手套。同时利用Node.JS构建服务器,使用node-serial port接收串口数据,并使用Socket.io建立远程实时连接。

  18. Effects of probiotic Lactobacillus rhamnosus GG and Propionibacterium freudenreichii ssp. shermanii JS supplementation on intestinal and systemic markers of inflammation in ApoE*3Leiden mice consuming a high-fat diet.

    Science.gov (United States)

    Oksaharju, Anna; Kooistra, Teake; Kleemann, Robert; van Duyvenvoorde, Wim; Miettinen, Minja; Lappalainen, Jani; Lindstedt, Ken A; Kovanen, Petri T; Korpela, Riitta; Kekkonen, Riina A

    2013-07-14

    A high-fat diet disturbs the composition and function of the gut microbiota and generates local gut-associated and also systemic responses. Intestinal mast cells, for their part, secrete mediators which play a role in the orchestration of physiological and immunological functions of the intestine. Probiotic bacteria, again, help to maintain the homeostasis of the gut microbiota by protecting the gut epithelium and regulating the local immune system. In the present study, we explored the effects of two probiotic bacteria, Lactobacillus rhamnosus GG (GG) and Propionibacterium freudenreichii spp. shermanii JS (PJS), on high fat-fed ApoE*3Leiden mice by estimating the mast cell numbers and the immunoreactivity of TNF-α and IL-10 in the intestine, as well as plasma levels of several markers of inflammation and parameters of lipid metabolism. We found that mice that received GG and PJS exhibited significantly lower numbers of intestinal mast cells compared with control mice. PJS lowered intestinal immunoreactivity of TNF-α, while GG increased intestinal IL-10. PJS was also observed to lower the plasma levels of markers of inflammation including vascular cell adhesion molecule 1, and also the amount of gonadal adipose tissue. GG lowered alanine aminotransferase, a marker of hepatocellular activation. Collectively, these data demonstrate that probiotic GG and PJS tend to down-regulate both intestinal and systemic pro-inflammatory changes induced by a high-fat diet in this humanised mouse model.

  19. 基于ExtJS的高校研究生学位论文双盲评审系统的设计与实现%Design and Implementation of Thesis Evaluation System Based on ExtJS

    Institute of Scientific and Technical Information of China (English)

    邢飞燕; 施佺; 胡祖辉

    2015-01-01

    Aims at the requirements of the graduate degree thesis evaluation, expounds the design and implementation of thesis evaluation system based on ExtJS, and introduces the relevant function modules, gives the key technology. The system has many advantages such as distinct interface and easy manipulation. The system not only reduces the workload and cost management, but also improves the work efficiency and quality.%针对当前高校研究生学位论文盲审工作的需求,详细分析并设计基于ExtJS技术的研究生学位论文双盲评审系统的相关功能模块及其实现的关键技术。该系统界面美观,操作方便,不仅减少开发的工作量与管理的成本,同时也大大提高工作效率和质量。

  20. Phase behavior and molecular thermodynamics of coacervation in oppositely charged polyelectrolyte/surfactant systems: a cationic polymer JR 400 and anionic surfactant SDS mixture.

    Science.gov (United States)

    Li, Dongcui; Kelkar, Manish S; Wagner, Norman J

    2012-07-17

    Coacervation in mixtures of polyelectrolytes and surfactants with opposite charge is common in nature and is also technologically important to consumer health care products. To understand the complexation behavior of these systems better, we combine multiple experimental techniques to systematically study the polymer/surfactant binding interactions and the phase behavior of anionic sodium dodecyl sulfate (SDS) surfactant in cationic JR 400 polymer aqueous solutions. The phase-behavior study resolves a discrepancy in the literature by identifying a metastable phase between the differing redissolution phase boundaries reported in the literature for the surfactant-rich regime. Isothermal titration calorimetry analyzed within the framework of the simple Satake-Yang model identifies binding parameters for the surfactant-lean phase, whereas a calculation for polymer-bound micelles coexisting with free micelles is analyzed in the surfactant-rich redissolution regime. This analysis provides a preliminary understanding of the interactions governing the observed phase behavior. The resulting thermodynamic properties, including binding constants and the molar Gibbs free energies, enthalpies, and entropies, identify the relative importance of both hydrophobic and electrostatic interactions and provide a first approximation for the corresponding microstructures in the different phases. Our study also addresses the stability and metastability of oppositely charged polyelectrolytes and surfactant mixtures.

  1. Applied Mathematics in the Humanities: Review of Nonparametric Statistics for the Behavioral Sciences by Sidney Siegel and N. John Castellan, Jr. (2nd ed., 1988

    Directory of Open Access Journals (Sweden)

    Paul H. Grawe

    2016-01-01

    Full Text Available Sydney Siegel and N. John Castellan, Jr. Nonparametric Statistics for the Behavioral Sciences, Second Edition (New York NY: McGraw Hill, 1988. 399 pp. ISBN: 9780070573574. Almost 60 years ago, Sidney Siegel wrote a stellar book helping anyone in academe to use nonparametric statistics, but ironically, 60 years after that achievement, American higher education confesses itself to be in the worst Quantitative Teaching Crisis of all time. The key clue to solving that crisis may be in Siegel and Castellan’s title, Nonparametric Statistics for the Behavioral Sciences, which quietly and perhaps unconsciously excludes the Humanities. Yet it is in humanistic realities that students read, write, and think. This book review considers what could be done if the Humanities were made aware of the enormous power of nonparametric statistics for advancing both their disciplines and their students’ ability to think quantitatively. A potentially revolutionary, humanistic, nonparametric finding is considered in detail along with a brief account of tens of humanistic discoveries deriving from Siegel and Castellan’s impetus.

  2. Nobel Prize in Physics 1993 "for the discovery of a new type of pulsar, a discovery that has opened up new possibilities for the study of gravitation" : Russell A. Hulse and Joseph H. Taylor Jr.

    CERN Multimedia

    1994-01-01

    Prof. J. H. Taylor Jr. presents "Binary pulsars and relativistic gravity" Spinning freely on their axes, and emitting radio noise detectable over interastellar distances, pulsars make extraordinarily stable natural clocks. Detailed comparisons of""pulsar time" with time kept by atomic clocks on Earth have opened the way for tests of gravity under conditions much more relativistic than found anywhere within the solar system. Among other results,these experiments have demonstrated the existence,quadrupolar nature, and propagation speed of gravitational waves.

  3. Identification of an isolate of fowl adenovirus group Ⅰ virus%Ⅰ群禽腺病毒江苏分离株(FAVI-JS)的分离鉴定

    Institute of Scientific and Technical Information of China (English)

    何秀苗; 张科; 秦爱建; 金文杰; 刘岳龙; 陈溥言

    2005-01-01

    通过形态学、致细胞病变和序列比较等对一株疑为Ⅰ群禽腺病毒江苏分离株FAVI-JS进行了鉴定,试验结果表明:该病毒为球形、无囊膜、二十面体对称,直径为70 nm~80nm;不具有凝集鸡、鸭、鹅红细胞的能力但可以凝集大鼠红细胞.在鸡胚肾细胞(CEK)上可致细胞变圆,折光性增强等病变;通过PCR方法扩增出的FAVI-JS L、R、ITR三个片段,经过测序分析并与GenBank上发表的属于血清Ⅰ型的CELO病毒、FAV-1、FAV-A和血清8型的禽腺病毒(FAV-8)全基因组的相应序列比较,FAVI-JS与Ⅰ群禽腺病毒各毒株在三个片段上同源性都很高,其中与血清Ⅰ型的同源性高达96%以上,在根据对遗传上具有重要意义的ITR序列绘制的遗传进行树分析,FAVI-JS与Ⅲ群禽腺病毒EDS、Y81G4株明显属于不同的分支,而与群禽腺病毒,特别是与血清Ⅰ型的禽腺病毒更接近,这些结果证明,FAVI-JS确为Ⅰ群禽腺病毒.

  4. Prótesis de cuerpo vertebral JR: dispositivo modular, anatómico y expandible, con función de jaula y placa diseñada ad hoc para estabilizar la columna después de corpectomía Prótese do corpo vertebral JR: dispositivo modular, anatômico e expansível, com função de jaula e placa desenhada ad hoc para estabilizar a coluna depois da corpectomia JR vertebral body prosthesis: a modular, anatomical and expandable device, with cage function and plate dual designed ad hoc for spine stabilization after corpectomy

    OpenAIRE

    2009-01-01

    INTRODUCCIÓN: debido a los resultados clínicos no satisfactorios con instrumentaciones posteriores en los casos de tumor vertebral y a las carencias económicas de nuestros pacientes para adquirir los sistemas disponibles en el mercado, fue diseñada una prótesis de cuerpo vertebral para estabilizar la columna después de una corpectomía. OBJETIVO: describir las características estructurales y funcionales de la prótesis JR, las pruebas biomecánicas en cadáver y la técnica quirúrgica en el pacien...

  5. Web app testing using Knockout.JS

    CERN Document Server

    Messora, Roberto

    2014-01-01

    If you are a JavaScript developer, beginner, or an expert who wants to improve quality standards in terms of solutions design and functional verification, this book is for you. Basic understanding of web development, HTML, and JavaScript is required.

  6. Data visualization with d3.js

    CERN Document Server

    Teller, Swizec

    2013-01-01

    This book is a mini tutorial with plenty of code examples and strategies to give you many options when building your own visualizations.This book is ideal for anyone interested in data visualization. Some rudimentary knowledge of JavaScript is required.

  7. Data visualization with D3.js cookbook

    CERN Document Server

    Zhu, Nick Qi

    2013-01-01

    Packed with practical recipes, this is a step-by-step guide to learning data visualization with D3 with the help of detailed illustrations and code samples.If you are a developer familiar with HTML, CSS, and JavaScript, and you wish to get the most out of D3, then this book is for you. This book can also serve as a desktop quick-reference guide for experienced data visualization developers.

  8. Learning AngularJS for .NET developers

    CERN Document Server

    Pop, Alex

    2014-01-01

    This is a step-by-step, example-driven guide that uses a gradual introduction of concepts; most of the chapters also contain an annotated exploration of how to build a specific part of a production-ready application. If you are a .NET developer that has already built web applications or web services with a fundamental knowledge of HTML, JavaScript, and CSS, and want to explore single-page applications, then this book will give you a great start. The frameworks, tools, and libraries mentioned here will make you productive and minimize the friction usually associated with building server-side we

  9. Joint Service Solvent Substitution (JS3)

    Science.gov (United States)

    2012-05-01

    Cleaning Alternatives • “Standard Protocol for Selecting General Cleaning Agents and Processes” Oct 1996 • “Performance Test of ChemFree Enzyme ...Based Aqueous Solvent”, Feb 1999 • “Armed Services Test Protocol for Alternative Cleaner Performance Validation” May 1999 Approved for Public...Release; Distribution Unlimited NFESC Gun Cleaning Effort • “USN/USMC Aqueous Weapons Cleaner Test Protocol”, February 2000 2001 P2 Conference

  10. J.R. Leibowitz: Hidden Harmony. The Connected Worlds of Physics and Art.. The Johns Hopkins University Press, 2008. ISBN-13: 978-0-8018-8866-3, ISBN-10: 0-8018-8866-2. 148 pages, hardcover, 27 colour pictures, 22 black-and-white figures, 8.9×7.2×0.7 inches

    Science.gov (United States)

    de Haro, Sebastian; van Lier, Thomas

    2009-04-01

    The book Hidden Harmony—The Connected Worlds of Physics and Art by J.R. Leibowitz is critically reviewed. The book is intended for a general audience and does not assume prior knowledge of physics or the arts.

  11. Design and implementation of the configuration system of cluster job scheduling policy based on ExtJs%基于ExtJs的集群作业调度策略配置系统的设计与实现

    Institute of Scientific and Technical Information of China (English)

    王小龙; 刘光明; 赵志威

    2015-01-01

    Based on ExtJs framework, using javabean, jsp and open source database Mysql, this pa-per has designed and implemented a configuration system of cluster job scheduling policy aim at the com-plexity and fallibility of the scheduling policy configuration of PBS in order to reap the cluster perform-ance. This paper sovled the technical problems such as the selection of controls for chosen scheduling policy, the combination of front-end process and back-end process for the input parameters verifica-tion, the generation of scheduling policy combinations in the interface file, user information paged-dis-play , focusing on the implementation of remote configuration and automatic generation of sophisticated job-scheduling policies. The system’ s major modules design idea, the core function and their implementa-tion method are introduced in detail. The running results show that the system improves the efficiency of the scheduling policy configuration work of high performance computing clusters adopting PBS, improve the accuracy of sophisticated job-scheduling policies generated.%为充分发挥集群系统的性能,针对PBS调度模块配置调度策略工作繁复、易于出错的问题,该文基于ExtJs框架,采用javabean、jsp、Mysql等技术设计并实现了一种集群作业调度策略配置系统。该系统解决了针对选定辅助策略的控件选取、输入参数的前后台联合校验、针对接口文件的组合调度策略生成、用户数据的分页显示等技术问题,重点实现了PBS的组合调度策略的远程配置及自动生成的功能。详细介绍了系统主要模块的设计思路、核心功能及实现方法。运行结果表明,该系统能够有效提高使用PBS的高性能计算集群的调度策略配置工作的效率,提高生成的较复杂的调度策略的正确率。

  12. Biodegradation of 3-Nitrotyrosine by Burkholderia sp. Strain JS165 and Variovorax paradoxus JS171

    Science.gov (United States)

    2006-02-01

    and B. Minambres. 2004. The homogentisate pathway: a central catabolic pathway involved in the degradation of L- phenylalanine , L-tyrosine, and 3...acetate-3- hydroxylase . A two-protein component enzyme. J. Biol. Chem. 267:25848–25855. 4. Bruhn, C., H. Lenke, and H.-J. Knackmuss. 1987. Nitrosubstituted

  13. Eurohüved rakenduvad järk-järgult / Paavo Palk ; interv. Toomas Mattson

    Index Scriptorium Estoniae

    Palk, Paavo, 1968-

    2003-01-01

    Ilmunud ka: Estonija 17. september lk. 4. Riigikantselei Euroopa Liidu infosekretariaadi nõunik Paavo Palk selgitab intervjuus Eesti EL-iga liitumisest tulenevaid muutusi. Skeem: Mida toob euroliitu astumine Eestile lähiaastate jooksul

  14. Rüütli veto tõrjumine sõltub Keskerakonna ühtsusest / Toomas Mattson

    Index Scriptorium Estoniae

    Mattson, Toomas, 1970-

    2004-01-01

    Euroopa parlamendi valimiste avatud nimekirju pooldavad Res Publica, Isamaaliidu ja Sotsiaaldemokraatliku Erakonna poliitikud. Postimehe andmetel valitsevad Keskerakonnas erimeelsused. Vt. samas: President kasutas esimest korda poliitilist argumenti

  15. Rüütli veto tõrjumine sõltub Keskerakonna ühtsusest / Toomas Mattson

    Index Scriptorium Estoniae

    Mattson, Toomas, 1970-

    2004-01-01

    Euroopa Parlamendi valimiste avatud nimekirju pooldavad Res Publica, Isamaaliidu ja Sotsiaaldemokraatliku Erakonna poliitikud, Postimehe andmetel valitsevad Keskerakonnas erimeelsused. Lisa: Avatud ja suletud nimekirjad. Vt. samas: President kasutas esimest korda poliitilist argumenti

  16. Vaher seob Türgi europüüdlused jätkuvalt kurdi keele olukorraga / Toomas Mattson

    Index Scriptorium Estoniae

    Mattson, Toomas, 1970-

    2003-01-01

    Justiitsminister Ken-Marti Vaher kohtus Türgi suursaadikuga Ömer Altugiga, kes selgitas oma riigi keelepoliitikat ja edu inimõiguste vallas. K.-M. Vaheri seisukohast, et Eesti peaks Türgit takistama EL-iga liitumast kurdi keele ahistamise pärast

  17. Tõestamata kahtlused heidavad varju : Tiit Kuusiku vahi alt vabastamise eest maksmine on vaid väidetav / Toomas Mattson

    Index Scriptorium Estoniae

    Mattson, Toomas, 1970-

    1997-01-01

    Politsei salajaste agentuuriteadete avalikustamine on ohtlik. K. Pikaro infobüroo Ius Dicere läbiotsimisel leitud agentuuriteade failist, mis käsitleb relvaärimehe T. Kuusik, N. Seli, Ü. Hage suhteid

  18. Rüütli veto tõrjumine sõltub Keskerakonna ühtsusest / Toomas Mattson

    Index Scriptorium Estoniae

    Mattson, Toomas, 1970-

    2004-01-01

    Euroopa parlamendi valimiste avatud nimekirju pooldavad Res Publica, Isamaaliidu ja Sotsiaaldemokraatliku Erakonna poliitikud. Postimehe andmetel valitsevad Keskerakonnas erimeelsused. Vt. samas: President kasutas esimest korda poliitilist argumenti

  19. Rüütli veto tõrjumine sõltub Keskerakonna ühtsusest / Toomas Mattson

    Index Scriptorium Estoniae

    Mattson, Toomas, 1970-

    2004-01-01

    Euroopa Parlamendi valimiste avatud nimekirju pooldavad Res Publica, Isamaaliidu ja Sotsiaaldemokraatliku Erakonna poliitikud, Postimehe andmetel valitsevad Keskerakonnas erimeelsused. Lisa: Avatud ja suletud nimekirjad. Vt. samas: President kasutas esimest korda poliitilist argumenti

  20. MAIL3.1 : a computer program generating cross section sets for SIMCRI, ANISN-JR, KENO IV, KENO V, MULTI-KENO, MULTI-KENO-2 and MULTI-KENO-3.0

    Energy Technology Data Exchange (ETDEWEB)

    Suyama, Kenya; Komuro, Yuichi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Takada, Tomoyuki; Kawasaki, Hiromitsu; Ouchi, Keisuke

    1998-02-01

    This report is a user`s manual of the computer program MAIL3.1 which generates various types of cross section sets for neutron transport programs such as SIMCRI, ANISN-JR, KENO IV, KENO V, MULTI-KENO, MULTI-KENO-2 and MULTI-KENO-3.0. MAIL3.1 is a revised version of MAIL3.0 that was opened in 1990. It has all of abilities of MAIL3.0 and has two more functions as shown in following. 1. AMPX-type cross section set generating function for KENO V. 2. Enhanced function for user of 16 group Hansen-Roach library. (author)

  1. Study on Polymer(JR)Cement Resisting Corrosion of Corrosive Performance by Carbon Dioxide%聚合物(JR)水泥抗二氧化碳腐蚀性能研究

    Institute of Scientific and Technical Information of China (English)

    王杰; 兰新生; 张力; 苏璟; 叶春燕

    2015-01-01

    This paper studies that the microstructure, changes of the composition and corrosion ratio, strength and permeability of cement stone before and after corrosion were analyzed with the method of X-ray diffraction(XRD),scanning electron microscope (SEM) and chemistry, The discussion that concentration of CO2 and temperature have effect on the cement corrosion characteristics and polymer JR resistances CO2 corrosion of mechanism. The results show the microstructure scanning seen a layer of impermeable membrane on cement surface by adding polymer JR, The corrosion products is the reaction of CO2 and a small amount of cement in the Ca(OH)2 and C-S-H by XRD;The internal structure and cementations materials of corrosion cement stone is not damaged. The polymer JR can effectively reduces the permeability of cement stone;Increasing the concentration of CO2 will intensify the corrosion rate, the loss of strength of cement stone and the increasing of permeability;The corrosion cement has a significantly larger turning point as the concentration of CO2 between 0.15 and 0.2. The polymer of cement has good effects of anti CO2 corrosion when the concentration of CO2 is less than 0.15;Under a certain concentration of CO2, the relationship between corrosion temperature and corrosion ratio is quadratics;Being covered non permeable polymer membranes on surface of cement stone and being filled polymer particles in cement stone pore have increased polymer JR of cement stone resistance corrosion of CO2.%本文利用化学、XRD和SEM等手段分析聚合物JR水泥腐蚀后的腐蚀率、强度、渗透率及水泥石微观结构和组成变化,探讨CO2浓度、腐蚀温度对聚合物JR水泥腐蚀性能影响和抗CO2腐蚀机理。结果表明:掺加聚合物JR后,SEM观察在水泥石表面上形成一层非渗透性膜,腐蚀后产物经XRD分析,水泥石中只有少量的Ca(OH)2和C-S-H碱性物质与CO2发生反应;腐蚀后水泥石内部结构和胶

  2. Elementary Properties of the Nematicidal Crude Toxin Produced by Bacillus amyloliquefaciens JK-JS3%一株毒杀松材线虫的解淀粉芽孢杆菌活性物质的基本性质

    Institute of Scientific and Technical Information of China (English)

    朱丽梅; 吴小芹; 陈江天; 徐旭凌

    2009-01-01

    从马尾松林中筛选出的解淀粉芽孢杆菌Bacillus amyloliquefaciens JK-JS3菌株对松材线虫Bursaphelenchus xylophilus具有较高杀线活性.本试验对JK-JS3菌株分泌的杀线活性物质的基本性质进行了研究.结果表明:该菌株产生的杀线组分是可随水分一同蒸发的非蛋白质类物质;其吸收峰在190nm到200nm之间;常温25℃和冷藏4℃下保存60d仍能保持杀线活性;不同温度和pH条件对其杀线组分的活性有影响,加热会降低其活性,碱性条件下具有较高的杀线活性;石油醚、氯仿、乙酸乙酯等有机溶剂不能将其活性物质从粗提液中提取.%Bacillus amyloliquefaciens JK-JS3, isolated from the leaf of the Pinus massoniana in Mount Zijin, has high nematicidal activity to Bursaphelenchus xylophilus. In order to isolate and purify the ne-maticidal components, the elementary characteristics of the nematicidal crude toxin have been studied in our experiment. The results indicated that the nematicidal toxin is not a protein which can be evaporated with the water and its maximum optical absorption is from 190 to 220 nm. The nematicidal activity of the toxin can sustain for a long period at 25 ℃ and 4 ℃. High temperature and pH condition can affect its nematicidal activity. It has strong nematicidal activity at the alkalinity condition. The nematicidal components can not be dissolved in the organic solvents such as petroleum ether, chloroform and ethyl acetate.

  3. Adult Still's disease

    Science.gov (United States)

    ... AJ, Smolen JS, Weinblatt ME, Weisman MH, eds. Rheumatology . 6th ed. Philadelphia, PA: Elsevier Mosby; 2015:chap ... Dell JR, eds. Kelley and Firestein's Textbook of Rheumatology . 10th ed. Philadelphia, PA: Elsevier; 2017:chap 43. ...

  4. Cryoglobulinemia

    Science.gov (United States)

    ... AJ, Smolen JS, Weinblatt ME, Weisman MH, eds. Rheumatology . 6th ed. Philadelphia, PA: Elsevier Mosby; 2015:chap ... Dell JR, eds. Kelley and Firestein's Textbook of Rheumatology . 10th ed. Philadelphia, PA: Elsevier Saunders; 2017:chap ...

  5. Isolation and Identification of Porcine Transmissible Gastroenteritis Virus JS2012 Strain and Clone and Sequence Analysis of Its S Complete Genome%猪传染性胃肠炎病毒江苏株的分离与鉴定及其S基因序列分析

    Institute of Scientific and Technical Information of China (English)

    郭容利; 倪艳秀; 温立斌; 李彬; 王小敏; 俞正玉; 何孔旺

    2013-01-01

    By serial passaging on ST cells ,a transmissible gastroenteritis virus (TGEV)strain(TGEV JS2012)was obtained from intestinal contents of died piglets with clinical diarrhea symptom .This virus was proved to be TGEV by RT-PCR,direct immunofluorescence and animal regression test .The S gene of TGEV JS2012 strain primary aassages (P1TS)and the fiftith passages(P50TS),were amplified by PCR and then sequenced .Comparison of the S gene se-quences of P1TS and P50TS with 18 published TGEV strains with different origins showed that they can share 96.0%-99.9%homology of nucleotide sequences and 96 .5%-99 .9%homology of amino acids .Furthermore ,the results of the phylogenetic tree analysis demonstrated that there was a close genetic relationship between P 1 TS strain and HN2002 or Miller M6 strain isolated from China and America respectively .Generally the result indicated the varia-tion of S gene between strains of different origins was not so obvious .The result also showed that a deletion of six bases happened in 1 124-1 129 location of the S gene of P50TS seemed to be similar to Purdue P115 strain which is an attenuated strain ,indicating this deletion perhaps is related to the reduced virulence of TGEV .%应用ST细胞,从临床上表现为腹泻症状的病死仔猪肠内容物中分离得到一株病毒,并对该病毒进行RT-PCR,直接免疫荧光与动物回归等试验,证实该病毒为猪传染性胃肠炎病毒(TGEV),命名为JS2012株。应用PCR方法克隆出其初代(P1TS)与50代(P50TS)的S基因片段,进行序列测定,并将该基因序列与已发表的18个不同来源的TGEV毒株进行同源性和亲缘关系的比较分析。结果表明,各毒株间核苷酸同源性为96.0%~99.9%,氨基酸的同源性为96.5%~99.9%。 TGEVJS201PITS株与中国江苏省HN2002株和美国Miller M6亲缘较近,表明不同地区分离毒株的S基因差异不大,而与P1TS相比,P50TS的S基因在1124~1129

  6. Digitally Controlled 4-Phase Bi-Directional Interleaved Dc-Dc Converter with Coupled Inductors / Digitāli Vadāms 4 Fāžu Divvirziena Līdzstrāvas Pārveidotājs Ar Saistītajām Droselēm

    Science.gov (United States)

    Kroics, K.; Sirmelis, U.; Grigans, L.

    2015-08-01

    The main advantages of multiphase interleaved DC-DC converters over single-phase converters are reduced current stress and reduced output current ripple. Nevertheless, inductor current ripple cannot be reduced only by an interleaving method. The integrated magnetic structure can be used to solve this problem. In this paper, the application of 2-phase coupled inductor designed in a convenient way by using commercially manufactured coil formers and ferrite cores is analysed to develop a 4-phase interleaved DC-DC converter. The steady state phase and output current ripple in a boost mode of the interleaved bidirectional DC-DC converter with integrated magnetics are analysed. The prototype of the converter has been built. The experimental results of the current ripple are presented in the paper. Šajā rakstā piedāvāta magnētiski saistīta drosele, kas izveidota, izmantojot plaša patēriņa ferrīta serdi un tinuma formētāju. Izmantojot šādas droseles, var tikt izveidots vairākfāžu pārveidotājs ar mazām izejas un iejas strāvas pulsācijām, kā arī samazinātām strāvas pulsācijām droselē. Rakstā sīkāk apskatīts līdzstrāvas pārveidotājs, kas sastāv no četrām fāzēm. Šim gadījumam izvestas teorētiskās formulas strāvas pulsāciju aprēķinam, kā arī rakstā parādīti eksperimentālie rezultāti, kas iegūti, testējot prototipu. Teorētiskie rezultāti sakrīt ar eksperimentālajiem

  7. Prótesis de cuerpo vertebral JR: dispositivo modular, anatómico y expandible, con función de jaula y placa diseñada ad hoc para estabilizar la columna después de corpectomía Prótese do corpo vertebral JR: dispositivo modular, anatômico e expansível, com função de jaula e placa desenhada ad hoc para estabilizar a coluna depois da corpectomia JR vertebral body prosthesis: a modular, anatomical and expandable device, with cage function and plate dual designed ad hoc for spine stabilization after corpectomy

    Directory of Open Access Journals (Sweden)

    Juan José Ramírez Jiménez

    2009-06-01

    Full Text Available INTRODUCCIÓN: debido a los resultados clínicos no satisfactorios con instrumentaciones posteriores en los casos de tumor vertebral y a las carencias económicas de nuestros pacientes para adquirir los sistemas disponibles en el mercado, fue diseñada una prótesis de cuerpo vertebral para estabilizar la columna después de una corpectomía. OBJETIVO: describir las características estructurales y funcionales de la prótesis JR, las pruebas biomecánicas en cadáver y la técnica quirúrgica en el paciente. MÉTODOS: primeramente fue realizado un estudio anatómico detallado de los cuerpos vertebrales. Se obtuvo el diseño de un dispositivo modular, anatómico y expandible. Sus componentes una vez ensamblados hacen un implante con función dual de jaula y placa lateral expandibles. Posteriormente se efectuó un ensayo de propiedades biomecánicas en cadáver y se implantó un dispositivo en un paciente con metástasis en cuerpo vertebral. RESULTADOS: las radiografías que le fueron tomadas al cadáver, posterior a la colocación del implante, no mostraron pérdida de la fijación. Al levantar el cadáver se generaron momentos de flexión en sentido lateral con brazos de palanca de 80 cm de largo, por lo que la prótesis fue demandada en su punto más vulnerable con una fuerza de aproximadamente 588 N. Con la rotación, flexión y extensión forzadas, la estabilidad se conservó y no se visualizó movimiento del implante. Se colocó el dispositivo en una mujer de 50 años con cáncer metastásico de tiroides que afectaba L3. El dolor mejoró en el postoperatorio inmediato, así como su función motora que le permitió caminar con una columna estable e indolora por siete años. No se observó fracaso del implante. CONCLUSIÓN: la función dual de jaula y placa integrada en la prótesis de cuerpo vertebral establece una ventaja mecánica comparada con la función de la jaula y de la placa separadamente, ya que el diseño de la prótesis permite

  8. PROFESSOR ZDZISŁAW ŻYGULSKI JR.: AN OUTSTANDING PERSON, A GREAT PERSONALITY, A MUSEUM PROFESSIONAL, A RESEARCHER ON ANTIQUE WEAPONS, ORIENTAL ART AND EUROPEAN PAINTING (1921–2015

    Directory of Open Access Journals (Sweden)

    Teresa Grzybkowska

    2017-02-01

    Full Text Available Professor Zdzisław Żygulski Jr. (1921–2015 was one of the most prominent Polish art historians of the second half of the 20th century. He treated the history of art as a broadly understood science of mankind and his artistic achievements. His name was recognised in global research on antique weapons, and among experts on Rembrandt and Leonardo da Vinci. He studied museums and Oriental art. He wrote 35 books, about 200 articles, and numerous essays on art; he wrote for the daily press about his artistic journeys through Europe, Japan and the United States. He illustrated his publications with his own photographs, and had a large set of slides. Żygulski created many exhibitions both at home and abroad presenting Polish art in which armour and oriental elements played an important role. He spent his youth in Lvov, and was expatriated to Cracow in 1945 together with his wife, the pottery artist and painter Eva Voelpel. He studied English philology and history of art at the Jagiellonian University (UJ, and was a student under Adam Bochnak and Vojeslav Molè. He was linked to the Czartoryski Museum in Cracow for his whole life; he worked there from 1949 until 2010, for the great majority of time as curator of the Arms and Armour Section. He devoted his whole life to the world of this museum, and wrote about its history and collections. Together with Prof. Zbigniew Bocheński, he set up the Association of Lovers of Old Armour and Flags, over which he presided from 1972 to 1998. He set up the Polish school of the study of militaria. He was a renowned and charismatic member of the circle of international researchers and lovers of militaria. He wrote the key texts in this field: Broń w dawnej Polsce na tle uzbrojenia Europy i Bliskiego Wschodu [Weapons in old Poland compared to armaments in Europe and the Near East], Stara broń w polskich zbiorach [Old weapons in Polish armouries], Polski mundur wojskowy [Polish military uniforms] (together with H

  9. Henry P. McKean Jr. selecta

    CERN Document Server

    Moerbeke, Pierre; Moll, Victor

    2015-01-01

    This volume presents a selection of papers by Henry P. McKean, which illustrate the various areas in mathematics in which he has made seminal contributions. Topics covered include probability theory, integrable systems, geometry and financial mathematics. Each paper represents a contribution by Prof. McKean, either alone or together with other researchers, that has had a profound influence in the respective area.

  10. BatchJS: Implementing Batches in JavaScript

    NARCIS (Netherlands)

    Kasemier, D.

    2014-01-01

    None of our popular programming languages know how to handle distribution well. Yet our programs interact more and more with each other and our data resorts in databases and web services. Batches are a new addition to languages that can finally bring native support for distribution to our favourite

  11. Monen pelaajan HTML5-autopeli Node.js:llä

    OpenAIRE

    Turunen, Janne

    2014-01-01

    Tämän opinnäytetyön toimeksiantajana toimi Karelia-ammattikorkeakoulu. Työssä käydään läpi pelinkehitysprosessi, jossa suunnitellaan ja kehitetään reaaliaikainen monelle pelaajalle suunnattu HTML5-verkkopeliprototyyppi. Reaaliaikaisen moninpelin kehittäminen tuo pelinkehitykseen omat haasteensa, joita työssä myös käsitellään. Opinnäytetyön käytännön osuudessa toteutettiin monen pelaajan 2D-autopeliprototyyppi, jota pystyy pelaamaan selaimessa verkon välityksellä. Opinnäytetyössä käsitellä...

  12. Interactive client side data visualization with d3.js

    Science.gov (United States)

    Rodzianko, A.; Versteeg, R.; Johnson, D. V.; Soltanian, M. R.; Versteeg, O. J.; Girouard, M.

    2015-12-01

    Geoscience data associated with near surface research and operational sites is increasingly voluminous and heterogeneous (both in terms of providers and data types - e.g. geochemical, hydrological, geophysical, modeling data, of varying spatiotemporal characteristics). Such data allows scientists to investigate fundamental hydrological and geochemical processes relevant to agriculture, water resources and climate change. For scientists to easily share, model and interpret such data requires novel tools with capabilities for interactive data visualization. Under sponsorship of the US Department of Energy, Subsurface Insights is developing the Predictive Assimilative Framework (PAF): a cloud based subsurface monitoring platform which can manage, process and visualize large heterogeneous datasets. Over the last year we transitioned our visualization method from a server side approach (in which images and animations were generated using Jfreechart and Visit) to a client side one that utilizes the D3 Javascript library. Datasets are retrieved using web service calls to the server, returned as JSON objects and visualized within the browser. Users can interactively explore primary and secondary datasets from various field locations. Our current capabilities include interactive data contouring and heterogeneous time series data visualization. While this approach is very powerful and not necessarily unique, special attention needs to be paid to latency and responsiveness issues as well as to issues as cross browser code compatibility so that users have an identical, fluid and frustration-free experience across different computational platforms. We gratefully acknowledge support from the US Department of Energy under SBIR Award DOE DE-SC0009732, the use of data from the Lawrence Berkeley National Laboratory (LBNL) Sustainable Systems SFA Rifle field site and collaboration with LBNL SFA scientists.

  13. Getting started with Knockout.js for .NET developers

    CERN Document Server

    Akinshin, Andrey

    2015-01-01

    This book is intended for .NET developers who want to use the MVVM design pattern to create powerful client-side JavaScript linked to server-side C# logic. Basic experience with ASP.NET, Razor, and creating web applications is needed.

  14. AngularJS lietotnes migrācija uz Angular

    OpenAIRE

    Andrucis, Edgars

    2017-01-01

    Darbā tiek aprakstītas un apkopotas dažādas stratēģijas un pieejas “AngularJS” projektu migrācijai uz jauno “Angular” ietvaru. Tai skaitā dažādi migrāciju priekšdarbi un stratēģijas, kā lielā sprādziena migrācijas stratēģija un inkrementālā migrācijas stratēģija. Šīs stratēģijas tiek novērtētas aprakstot to trūkumus un priekšrocības. Balstoties uz tā, darba autors veica tīmekļa pieteikumu formu “AngularJS” lietotnes migrāciju uz jauno “Angular” ietvaru. Pēc kā tas novērtēja apkopoto informāci...

  15. Prótesis de cuerpo vertebral JR: dispositivo modular, anatómico y expandible, con función de jaula y placa diseñada ad hoc para estabilizar la columna después de corpectomía

    OpenAIRE

    2009-01-01

    INTRODUCCIÓN: debido a los resultados clínicos no satisfactorios con instrumentaciones posteriores en los casos de tumor vertebral y a las carencias económicas de nuestros pacientes para adquirir los sistemas disponibles en el mercado, fue diseñada una prótesis de cuerpo vertebral para estabilizar la columna después de una corpectomía. OBJETIVO: describir las características estructurales y funcionales de la prótesis JR, las pruebas biomecánicas en cadáver y la técnica quirúrgica en el pacien...

  16. Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1.

    Science.gov (United States)

    Gohain, Neelakshi; Tolbert, William D; Acharya, Priyamvada; Yu, Lei; Liu, Tongyun; Zhao, Pingsen; Orlandi, Chiara; Visciano, Maria L; Kamin-Lewis, Roberta; Sajadi, Mohammad M; Martin, Loïc; Robinson, James E; Kwong, Peter D; DeVico, Anthony L; Ray, Krishanu; Lewis, George K; Pazgier, Marzena

    2015-09-01

    Accumulating evidence indicates a role for Fc receptor (FcR)-mediated effector functions of antibodies, including antibody-dependent cell-mediated cytotoxicity (ADCC), in prevention of human immunodeficiency virus type 1 (HIV-1) acquisition and in postinfection control of viremia. Consequently, an understanding of the molecular basis for Env epitopes that constitute effective ADCC targets is of fundamental interest for humoral anti-HIV-1 immunity and for HIV-1 vaccine design. A substantial portion of FcR effector function of potentially protective anti-HIV-1 antibodies is directed toward nonneutralizing, transitional, CD4-inducible (CD4i) epitopes associated with the gp41-reactive region of gp120 (cluster A epitopes). Our previous studies defined the A32-like epitope within the cluster A region and mapped it to the highly conserved and mobile layers 1 and 2 of the gp120 inner domain within the C1-C2 regions of gp120. Here, we elucidate additional cluster A epitope structures, including an A32-like epitope, recognized by human monoclonal antibody (MAb) N60-i3, and a hybrid A32-C11-like epitope, recognized by rhesus macaque MAb JR4. These studies define for the first time a hybrid A32-C11-like epitope and map it to elements of both the A32-like subregion and the seven-layered β-sheet of the gp41-interactive region of gp120. These studies provide additional evidence that effective antibody-dependent effector function in the cluster A region depends on precise epitope targeting--a combination of epitope footprint and mode of antibody attachment. All together these findings help further an understanding of how cluster A epitopes are targeted by humoral responses. HIV/AIDS has claimed the lives of over 30 million people. Although antiretroviral drugs can control viral replication, no vaccine has yet been developed to prevent the spread of the disease. Studies of natural HIV-1 infection, simian immunodeficiency virus (SIV)- or simian-human immunodeficiency virus (SHIV

  17. Joaquim Mattoso Câmara Jr: um inovador Joaquim Mattoso Câmara Jr: innovator

    Directory of Open Access Journals (Sweden)

    Yonne Leite

    2004-01-01

    Full Text Available Neste texto são revistas as diferentes áreas de interesse de Mattoso Câmara - fonologia, morfologia, estilística - e enfatizados seus esforços para a institucionalização dos estudos lingüísticos no Brasil: a criação de uma disciplina em Lingüística Geral na década de 1930; o estabelecimento de um Setor Lingüístico no Museu Nacional, no Rio de Janeiro, em 1958; a fundação da ABRALIN, em 1969. O legado de Mattoso é revisitado do ponto de vista de quem foi sua aluna e testemunhou o percurso que, a partir do mestre, toda uma geração de lingüistas pioneiros percorreu. Entre outros: Carlos Eduardo Falcão Uchôa, Miriam Lemle, Leda Bisol, Jean Pierre Angenot, Paulino Vandresen, Eunice Pontes, Brian Head, Cléa Rameh, Eurico Back e a própria Yonne Leite.In this text we review Mattoso Câmara's different areas of interest - phonology, morphology, stylistics - emphasizing his efforts toward the institutionalization of linguistic studies in Brazil: the creation of the discipline of General Linguistics in the 1930s; the establishment of a Linguistic Sector at the Museu Nacional in Rio de Janeiro, in 1958; the foundation of the Brazilian Linguistics Association, ABRALIN, in 1969. Mattoso's legacy is revisited here from the point of view of someone who was his student and witnessed the path followed by a whole generation of pioneer linguists, inspired by the master. Among others: Carlos Eduardo Falcão Uchôa, Miriam Lemle, Leda Bisol, Jean Pierre Angenot, Paulino Vandresen, Eunice Pontes, Brian Head, Cléa Rameh, Eurico Back and Yonne Leite herself.

  18. Eesti suurima relvakaubandusafääri uurimine läheneb edukale lõpule / Jüri Vissak ; interv. Toomas Mattson

    Index Scriptorium Estoniae

    Vissak, Jüri

    1996-01-01

    Kolm kriminaalasja, mis käsitlevad seaduslikult Eestisse toodud ja siit ebaseaduslikult välja viidud tulirelvadega seotut. Ilmunud ka: Vetšernije Vesti, 23. jaan. 1996, lk. 5; Narvskaja Gazeta, 10. veebr. 1996, lk. 4

  19. 137 miljoni kroonist kärbet saadab kiremöll : Riigikogu reformib täna tudengite protestidest hoolimata radikaalselt sotsiaalhoolekande seadust / Toomas Mattson

    Index Scriptorium Estoniae

    Mattson, Toomas, 1970-

    2002-01-01

    Koalitsioon surub 10. detsembril 2002. a. Riigikogus läbi sotsiaalhoolekande seaduse muudatused, millega tudengid kaotavad 2003. a. eelarves toimetulekutoetustest ligi 70 miljonit krooni. Uue korra järgi loetakse toimetulekutoetuse määramisel kuni 24-aastased õpilased ja üliõpilased vanemate ülalpidamisel olevateks sõltumata sellest, kas nad elavad koos vanematega või mitte. Eesti Üliõpilaskondade Liit leiab, et selline seadusetäiendus rikub põhiseadust

  20. Proceedings of the Quantum Computation for Physical Modeling Workshop Held in North Falmouth, Massachusetts on October 18-19, 2000

    Science.gov (United States)

    2002-01-01

    than a few hundreds particles [ 17]. Although this statement can probably be challenged by modem HKsqPj = E (23) multiscale techniques (Achi Brandt ...Yu.A. Pashkin, J.S. Tsai, Nature 398 (1999) 786. [62] A. Berg, M. Dobers, R.R. Gerhards , K.V. Klitzing, Phys. Rev. [45] J.R. Friedman, V. Patel, W

  1. Occupational Exposure to Ionizing Radiation for Crews of Suborbital Spacecraft: Questions and Answers

    Science.gov (United States)

    2013-12-01

    Friedberg , Ph.D. (deceased), Paul Rogers, and Michael E. Wayda, FAA Civil Aerospace Medical Institute Oklahoma City, OK, for assistance in the... Friedberg W, Copeland K, Duke FE, Nicholas JS, Darden Jr EB, O’Brien III K. Radiation exposure of aircrews. Oc- cup Med: State of the Art Reviews

  2. Physicochemical and morphological properties of poly(aniline-co-pyrrole)

    CSIR Research Space (South Africa)

    Mavundla, SE

    2010-01-01

    Full Text Available . [2] Skotheim T, Pomerantz M, Elsenbaumer RL, Reynolds JR, editors. Handbook of Conducting Polymers. 2nd edn. New York: Marcel Dekker; 1998; p 277. [3] Novak P, Muller K, Santhanam KSV, Hass O. Chem Rev 1997; 97: 207-281. [4] Miller JS. Adv...

  3. Obituaries: George McClelland Foster Jr. (1913-2006)

    National Research Council Canada - National Science Library

    Robert V Kemper; Stanley Brandes

    2007-01-01

    In more than 300 publications, he wrote about acculturation, fieldwork, peasant societies, pottery making, public health, social structure, technological change, theories of illness and wellness, and worldview...

  4. Keeping the Dream Alive. Dr. Martin Luther King, Jr.

    Science.gov (United States)

    Cassells, Linda; And Others

    1993-01-01

    Presents activities for teaching elementary students about Dr. Martin Luther King's life, the civil rights movement, and King's accomplishments. Suggestions include shoebox dioramas, acronym games, oral histories, multicultural awareness activities, pledge cards, community service projects, special commemorative ceremonies, and a book of dreams.…

  5. Freedom 7 the historic flight of Alan B. Shepard, Jr.

    CERN Document Server

    Burgess, Colin

    2014-01-01

    Inevitably, there are times in a nation’s history when its hopes, fears and confidence in its own destiny appear to hinge on the fate of a single person. One of these pivotal moments occurred on the early morning of May 5, 1961, when a 37-year-old test pilot squeezed himself into the confines of the tiny Mercury spacecraft that he had named Freedom 7. On that historic day, U.S. Navy Commander Alan Shepard carried with him the hopes, prayers, and anxieties of a nation as his Redstone rocket blasted free of the launch pad at Cape Canaveral, hurling him upwards on a 15-minute suborbital flight that also propelled the United States into the bold new frontier of human space exploration. This book tells the enthralling story of that pioeering flight as recalled by many of the participants in the Freedom 7 story, including Shepard himself, with anecdotal details and tales never before revealed in print. Although beaten into space just three weeks earlier by the Soviet cosmonaut Yuri Gagarin, Alan Shepard’s h...

  6. 76 FR 3819 - Martin Luther King, Jr., Federal Holiday, 2011

    Science.gov (United States)

    2011-01-20

    ... the President of the United States of America A Proclamation Half a century ago, America was moved by a young preacher who called a generation to action and forever changed the course of history. The... recognizing one of America's greatest visionary leaders, and we celebrate the life and legacy of Dr. King....

  7. 77 FR 2905 - Martin Luther King, Jr., Federal Holiday, 2012

    Science.gov (United States)

    2012-01-20

    ... understanding amid the voices of violence, hatred, and emotion.'' His example stirred men and women of all backgrounds to become foot soldiers for justice, and his leadership gave them the courage to refuse the... meet the challenges of our time--from fixing our schools so every child gets a world-class education to...

  8. Obituary: Harding Eugene (Gene) Smith, Jr., 1947-2007

    Science.gov (United States)

    Lonsdale, Carol; Soifer, Tom

    2009-01-01

    Harding Eugene Smith Junior, or Gene, as he was known to family, friends, and colleagues, passed away after an automobile accident in Encinitas, California, on 16 August 2007. He was 60 years old. Gene had recently retired from UCSD after thirty years of service. A memorial service was held at Quail Botanical Gardens in Encinitas, California, on 23 August 2007. A web page is dedicated to his memory at http://harding.smith.muchloved.com, where contributions of memories are invited. Gene was born in San Jose, California in 1947, to Harding Eugene Smith Senior, and Bernice Smith (nee Smith). Harding Smith Senior was an air-force navigator; therefore Gene spent his childhood moving from one air-force base to another. Although an only child, Gene was very close to his cousin Meg, whom he lived nearby to in Gilroy for a time, and the two were like brother and sister. The elder Harding Smith was lost in action over Cambodia in the mid-sixties. Gene was a dedicated student, a boy scout, and a Presidential Scholar. He majored in Physics at Caltech, where he also took a lively interest in the football team and the Glee Club, and was elected a House Officer. To his close friends, he was known at Caltech as Smitty, and the closest of them was Rob Drew, who gave a glimpse into that period of Gene's life at the memorial: "Gene arrived early at campus his first year, in response to an invitation to join the football team. Gene's size and features reminded the head coach of a long-forgotten player named 'Johnson.' After a few days of confusion, Gene simply replaced the name on his helmet. 'Johnson!' coach would yell, 'get in there!' If Johnson was going to get to play, Gene was going to be the best Johnson available!" Gene spent the summer of 1966 working at Kitt Peak, where his lifetime love of observing with ground-based telescopes began, though he learned some things the hard way, such as the fact that trying to squeeze 40,000 numbers onto a computer that stored only 32,000 resulted in blown fuses. In a final letter of that summer back to Drew he wrote: "My summer is now complete. I have achieved the highest pinnacle in my quest for fulfillment. Striking a blow for humanity I just blew the whole Kitt Peak CDC3200 computer system. Those fuses were nothing compared to this!" Gene's graduate work, on the metal abundances in HII regions of nearby galaxies, was done at Berkeley, where Hyron Spinrad was his thesis advisor. He loved observing and spent numerous fun nights at Lick, Kitt Peak, Cerro Tololo, Keck, and many other observatories. He joined Margaret Burbidge at UCSD for a postdoctoral fellowship, and joined the teaching faculty there in 1978. Gene spent his entire professional career at UCSD. His research ranged from the study of quasar absorptions lines to the astrophysics of Ultra-luminous Infrared Galaxies. He was a key participant in UC-wide astronomy support, including being the chair of the science-advisory committee for the Ten Meter Telescope project, which later "morphed" into the Keck Observatory. His contributions to enabling that project were both essential and unheralded. Gene was a dedicated and enthusiastic teacher. One of his favorite undergraduate classes gave him the opportunity to dress up in Renaissance garb and pretend to be Galileo, while the experiment most loved by his students was when they got to attempt to drop an egg on his head from several stories high. Gene was also an outstanding advisor and mentor, and both his first post-doc, Rick Puetter, and his last graduate student, Brian Siana, were able to attend his memorial service and provide some special memories of their experiences with him. Rick recalled a memorable trip to Cerro Tololo when they packed up two infrared spectrometers for the trip, and everything conceivable went wrong, from inspections at the airport to spectrometer parts broken on the plane and instrument failures at the observatory, to finally being completely clouded out. Brian recounted: "I spent countless cloudy nights listening to Gene's stories that began with "When men were men

  9. NEA President Don Morrison Interviews Mrs. Martin Luther King, Jr.

    Science.gov (United States)

    Morrison, Don

    1972-01-01

    Civil rights leader's widow suggests activities conducive to peaceful social change, including Foundation-released film. Describes King Atlanta Center's plans for teacher-training in nonviolent means to attack poverty, fortify women's rights, improve race relations and black representation, end segregation outside South. (PD)

  10. Aiming at Targets: The Autobiography of Robert C. Seamans, Jr.

    Science.gov (United States)

    Seamans, Robert C., Jr.

    1996-01-01

    Bob Seamans originally was inspired to write this book for his family and friends. That is a large audience. By his own count his immediate family numbers twenty-four, not counting brothers and cousins and their families. His friends are uncounted but surely run to hundreds. As one of them and as a colleague at NASA, I am pleased and honored that he asked me to write this foreword. While written in Bob's unique and informal style, this autobiography has significance for many readers beyond his large circles of family and friends. Leaders and students of large, complex technological endeavors should be able to learn much from reading how Bob faced the daunting technical and management challenges in his career. As the title of this book implies, Bob has always set high goals for himself and then kept his eyes focused on both the necessary details and the broader picture. His ability to shift smoothly among jobs that required seemingly disparate abilities and skills speaks volumes about his insight, dedication, and enthusiasm for achievement. The book spans a truly remarkable life story. Bob first takes us through his growing up, education, and early professional and family life. Next he focuses on the crucial years when he was the general manager of NASA. Then he moves on to his career in the top jobs at the Air Force, the National Academy of Engineering, and the Energy Research and Development Administration. Finally, he touches on his later leadership activities in the academic and business worlds. Aiming at Targets is a series of fascinating topical vignettes covering his professional life. Taken together, like broad brushstrokes in an impressionist painting, they give a better picture of Bob Seamans and his work than a detailed recitation of facts and dates could hope to do. This is a cheerful account of an interesting and successful career. The book is full of good stories, with many memorable characters. Like the proverbial sundial, it counts the sunny hours. It is a good read. But it has its serious side. Bob's career wasn't all fun. The Apollo 204 fire, which killed three astronauts, was a terrible climax to his time at NASA. As one who lived through those days with him, I can recall the trauma and special sense of responsibility he felt. His account of this period and of the sad deterioration of his relationship with his boss, Jim Webb, is both fair and generous. Those were not happy times, but they should not be allowed to overshadow the fact that in his seven years at NASA, Bob Seamans led the agency to its first successes and laid the groundwork for the great successes that came later.

  11. Kolmas võimalus : Veel JR 200 kirjanduselust / Ain Kaalep

    Index Scriptorium Estoniae

    Kaalep, Ain, 1926-

    1996-01-01

    Vastuseks Ott Arderi artiklile 'Laulu võimu täius ja viletsus', Looming, nr. 5, samuti Sirje Oleski artiklile 'Prooimion Ain Kaalepi elu- ja loominguloole', Looming, nr. 6. Ka Eerik Tederi uurimusest 'Suomenpojat Viron Kirjallisuudessa ja heidän teostensa vastaanotto Suomessa' (Jyväskylä, 1996)

  12. SAVEWS Jr. User’s Manual, Version 1.0

    Science.gov (United States)

    2014-04-01

    is more of a cosmetic fix than a true signal processing fix, but it can be handy in some situations. The reprocessing results (Figure 24) exhibit...Figure A1) consists of a Lowrance LSS-2 structure scan module and a 12-V DC power source housed in a waterproof case (Figure A2), a quick disconnect...swivel mount for the HDS unit, and a waterproof through- deck fitting for transducer and power connections (Figure A3). The system includes

  13. O talento para liderar, de Joseph Nye Jr.

    Directory of Open Access Journals (Sweden)

    Reinaldo Alencar Domingues

    2012-05-01

    Full Text Available Os constantes impasses políticos no cenário internacional têm criado uma sensação generalizada de urgência e de paralisia. As crises decisórias ressaltam simultaneamente a carência e a necessidade de fortes lideranças políticas.  A liderança é uma relação de poder melhor compreendida como um processo complexo constituído de três elementos: o líder, o público e o contexto que os envolve. Somente pela interação dessas três variáveis pode-se compreender as dinâmicas da mobilização dos recursos internos e a coordernação de forças necessárias para romper a inação política das relações internacionais contemporâneas.

  14. Dr. John H. Hopps Jr. Defense Research Scholars Program

    Science.gov (United States)

    2014-12-16

    Aparecio Peggins (Psychology) Past Research Experience • Attachment Styles in Romantic Relationships, University of New Hampshire (Summer 2011...Psychology Neurobiology of Circadian Entrainment Aparecio Peggins Duane Cooper Professor and Chair of Mathematics Mathematics student and

  15. Multiculturalism: An Analysis of Arthur Schlesinger, Jr. and Cornel West.

    Science.gov (United States)

    Lemaire, Laura

    1994-01-01

    Contrasts the social views presented in Arthur M. Schlesinger's "The Disuniting of America" with those of Cornel West's "Race Matters." Discusses issues such as diversity, separatism, and unity within a multicultural democracy. Concludes that educators should be informed about the views of both authors. (CFR)

  16. 77 FR 61003 - Stephen C. Delaney, Jr.: Debarment Order

    Science.gov (United States)

    2012-10-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND... and purchase, the offer of sale and purchase, and the intent to sell and purchase, fish with a market... purchase, and intent to sell and purchase, fish with a market value of approximately $8,000. The...

  17. Consumer Chemistry for Middle/Jr. High Students.

    Science.gov (United States)

    Rakow, Steven J.; And Others

    1984-01-01

    Objectives, materials needed, procedures, discussion questions, and follow-up activities are provided for five experiments. They include (1) testing for sugars; (2) comparing sugar to artificial sweeteners; (3) chewing gum scientifically; (4) soap making; and (5) making toothpaste. (JN)

  18. Obituary: Norman Hodgson Baker, Jr., 1931-2005

    Science.gov (United States)

    Helfand, David J.

    2005-12-01

    Norman H. Baker, a key contributor to the foundation of modern stellar pulsation theory and former editor of the "Astronomical Journal", died on 11 October 2005 in Watertown, New York near his beloved summer home in Natural Bridge. He succumbed to complications of Waldenstrom's macroglobulinemia, a bone marrow lymphoma that he had successfully surmounted for twenty-two years. Norm, as he was known to all, was born 23 October 1931 in Fergus Falls, Minnesota to Norman Hodgson and Jeannette (née Lieber) Baker. He attended the University of Minnesota where he met the first of many lifelong astronomical friends, Bill Erickson. He received his BA in 1952. He went on to do his PhD, "Radiation from Particle Interactions which Create Current," at Cornell University under Phil Morrison. He then moved to a postdoctoral position at the Max Planck Institut für Physik und Astrophysik in München with the intent of pursuing his work in plasma physics with Ludwig Biermann and Arnulf Schlüter. However, Rudolf (Rudi) Kippenhan snatched him away to pursue what became his lifelong interest, stellar physics. This was the dawn of the era in which electronic computers were becoming practical for scientific calculations, and Norm immediately adopted this new tool. Indeed, he remained at the forefront of computing technology throughout his life: He was certainly the first member of the Astronomy Department at Columbia to buy a Mac, and was undoubtedly one of the few emeritus professors in the world known by all the administrative staff as the first person to turn to when stumped by a computer problem. Following his first paper with Kippenhan on stellar rotation, Norm turned his attention to stellar pulsations, a topic he would pursue throughout his career. His 1962 paper in "Zeitschrift für Astrophysik" on pulsational models of Cepheids (Baker and Kippenhan 1962, 54, 155) is a classic in the field. The first figure displays the three dimensional model of the atmospheric absorption coefficient as a function of log P and log T. Sophisticated three-dimensional computer images being many years in the future, it was contructed from a folded and bent sheet of grid paper which was subsequently photographed. Using extensive numerical analysis, the paper showed that stars in the δ Cephei region of the H-R diagram were ``pulsationally unstable due to the destabilizing effect of the He+ region.'' This paper, along with those of Zhevakin, Cox, and Christy, established our modern understanding of pulsational instability in horizontal branch stars. His second paper with Kippenhan the following year brought convection into the problem; this topic became another lifelong theme of Norm's research that he subsequently pursued with Douglas Gough. His most cited work, carried out a decade later with van Albada, was an attempt to understand the properties of horizontal branch stars. It synthesized for the first time stellar evolution theory and the insights gained from studies of stellar pulsations. Between 1961 and 1965, Norm held no fewer than five positions. After a year on the west coast at the Convair Science Research Lab in San Diego, he landed in the New York area to pursue pulsations, oscillating among the Goddard Institute for Space Studies, the Institute for Advanced Study in Princeton, Yale, and New York University. In 1965, he was hired as an Assistant Professor in the Department of Astronomy at Columbia University by Lo Woltjer, and remained at Columbia until he retired in 2003. As a teacher, he was deeply appreciated by undergraduate and graduate students alike for lectures that were models of clarity, for his out-of-class assistance which was generous and unstinting, and for incorporating into his courses modern numerical techniques which served the students well throughout their careers. In 1975 when Woltjer returned to Europe, Norm took over the editorship of the "Astronomical Journal", a position he held (shared in the last few years with Leon Lucy) for a decade. His scrupulous integrity and forthright honesty served him, and the Society, well. Despite his scathing intolerance for administrative stupidity, he also managed to complete successfully a term as Chair of the Department of Astronomy. (This author, who currently holds the Chair and shares the intolerance, has yet to fathom the gracious equanimity Norm displayed.) His early interest in brewing beer during graduate school at Cornell (where he co-founded the Old Undershirt Brewing Company) was transformed in later life into an expertise in German wines. The precision that marked his research extended to every aspect of his private life. I had the distinct pleasure of subletting his apartment during my first year on the faculty at Columbia while he was on leave in Europe. We spent most of the year trying to imagine how we could ever restore it to the state of perfect organization in which we found it. Norm is survived by his wife and constant companion of thirty years, psychiatrist Doris Blum Nagel, by his sister Dr. Jean Trousdale, and brother Dr. Richard C. Baker, two nieces, three nephews, and by several generations of undergraduates, graduate students, postdocs, and colleagues who hold fond memories of his patience, kindness, humor, and quiet "joie de vivre".

  19. NEA President Don Morrison Interviews Mrs. Martin Luther King, Jr.

    Science.gov (United States)

    Morrison, Don

    1972-01-01

    Civil rights leader's widow suggests activities conducive to peaceful social change, including Foundation-released film. Describes King Atlanta Center's plans for teacher-training in nonviolent means to attack poverty, fortify women's rights, improve race relations and black representation, end segregation outside South. (PD)

  20. 75 FR 3839 - Martin Luther King, Jr., Federal Holiday, 2010

    Science.gov (United States)

    2010-01-22

    ... promise of economic and social justice because we stand on the shoulders of giants like Dr. King, yet our... ladders of opportunity by correcting social injustice, breaking the cycle of poverty in struggling... strongest weapon against injustice and inequality. Recognizing that our Nation has yet to reach Dr....

  1. William E. Edmonston, Jr.: Editor, 1968-1976.

    Science.gov (United States)

    Kihlstrom, John F; Frischholz, Edward J

    2010-10-01

    This article is part of an occasional series profiling editors of the American Journal of Clinical Hypnosis (AJCH). William E. Edmonston was the second editor, succeeding Milton H. Erickson. His research focused on the use of conditioning paradigms and psychophysiological measures to explore a wide variety of hypnotic phenomena, leading to a "neo-Pavlovian" theory of neutral hypnosis as physiological relaxation (anesis). A longtime professor of psychology at Colgate University, he created an interdisciplinary undergraduate major in neuroscience, and was named New York State College Professor of the Year in 1988. He gave the Journal a new look, and a greater balance of clinical and experimental papers. The article also provides background on George Barton Cutten, George H. Estabrooks, and Frank A. Pattie, pioneers of hypnosis who were linked to Edmonston.

  2. 78 FR 5247 - Martin Luther King, Jr., Federal Holiday, 2013

    Science.gov (United States)

    2013-01-24

    ... our country, and sent ripples throughout the world. Speaking to thousands upon thousands rallying for... does not roll in on the wheels of inevitability, but comes through continuous struggle.'' Throughout the 1950s and 1960s, he mobilized multitudes of men and women to take on a struggle for justice...

  3. a potential competitive tool for J&S Botswana (Pty) Ltd [case study

    African Journals Online (AJOL)

    ... businesses failing to survive the competition in the dynamic business environment. ... This work therefore outlines a customized methodology for formulating a manufacturing strategy through a strategic audit of a local case study company.

  4. http://www.bioline.org.br/js 15 Practices of Makerere University ...

    African Journals Online (AJOL)

    jen

    Conclusion: The students' responses highlight differences between institutional expectations of ... through work on the human body are thought to have ... emotional preparation for future clinical practice. ... what happens during the anatomy dissection practical. .... personal choice to observe, fear of allergic reactions to ...

  5. How do I love thee? Let me count the Js: implicit egotism and interpersonal attraction.

    Science.gov (United States)

    Jones, John T; Pelham, Brett W; Carvallo, Mauricio; Mirenberg, Matthew C

    2004-11-01

    From the perspective of implicit egotism people should gravitate toward others who resemble them because similar others activate people's positive, automatic associations about themselves. Four archival studies and 3 experiments supported this hypothesis. Studies 1-4 showed that people are disproportionately likely to marry others whose first or last names resemble their own. Studies 5-7 provided experimental support for implicit egotism. Participants were more attracted than usual to people (a) whose arbitrary experimental code numbers resembled their own birthday numbers, (b) whose surnames shared letters with their own surnames, and (c) whose jersey number had been paired, subliminally, with their own names. Discussion focuses on implications for implicit egotism, similarity, and interpersonal attraction. 2004 APA

  6. J.S. Mill and A. de Tocqueville: tow concepts of liberty

    Directory of Open Access Journals (Sweden)

    A. V. Tavadova

    2016-01-01

    Full Text Available This paper presents an analysis of the two concepts of freedom, one of which was developed in line with classical liberalism, the second within the conservative tradition. Individual freedom as the supreme value, good and the goal of social development was considered an English liberal thinker John Stuart Mill. Another approach found expression in the works of the brightest representatives of the French conservative thought of Alexis de Tocqueville. In despite of the similarity of some theses, this polemic initiated the development of the two traditions in understanding the concept of civil liberties, continues to create and maintain the discussion of modern theoretical sociology. The research methodology of these concepts, to better understand the fundamental essence of the dispute between liberals and conservatives, seeking to find a balance between individual freedom in various aspects of its expression and the public interest.

  7. Professional JavaScript Frameworks Prototype,YUI, ExtJS, Dojo and MooTools

    CERN Document Server

    Orchard, Leslie M; Koon, Scott

    2009-01-01

    As the industry-standard, must-know scripting language, JavaScript is supported by all major browsers and is increasingly the foundation of new web development technologies such as Ajax and JSON. This book offers a selection of some of the most active and most used JavaScript frameworks available, replete with practical examples and explanations of what each framework does best. You'll look at common web development tasks and discover how each framework approaches that set of tasks, as well as learn how to use the features of each framework and avoid potential pitfalls.

  8. 20 CFR 658.411 - Filing and assignment of JS-related complaints.

    Science.gov (United States)

    2010-04-01

    ... alleging unlawful discrimination by race, color, religion, national origin, sex, age, or physical or mental... alleging unlawful discrimination by race, color, religion, national origin, sex, age, physical or...

  9. http://www.bioline.org.br/js Childhood Bone and Soft Tissue ...

    African Journals Online (AJOL)

    www

    the developing countries, one child out of two with cancer will die because of this disease mostly because they ... and soft tissue tumours in children was done in the Surgery Departments of University. Teaching Hospitals .... rays already had pulmonary metastases on ... Four deaths had Osteosarcoma, one had. Ewing's ...

  10. Phenol degradation by halophilic fungal isolate JS4 and evaluation of its tolerance of heavy metals.

    Science.gov (United States)

    Jiang, Yu; Shang, Yu; Yang, Kai; Wang, Hongyu

    2016-02-01

    Phenol is one of the most common pollutants in many kinds of industrial wastewater, some of which are in high salinity, resulting in more difficulties of biodegradation. In this work, a halophilic strain capable of utilizing phenol as sole source of carbon and energy in both hypersaline and no-salt media was isolated and identified as genus Debaryomyces. The optimization of environmental parameters including phenol concentration, pH, dissolved oxygen as well as salinity was carried out and tolerance of heavy metals by the strain was evaluated. The strain Debaryomyces sp. was able to grow in culture when initial phenol concentration, pH, agitation and salinity were at wide ranges (0-1200 mg L(-1), 4.0-10.0, 50-200 rpm, 0 %-15 %, respectively). High removal efficiency was hardly affected in the presence of 5 mM of Zn (II) and Mn (II). Under optimal conditions (pH 6.0, 200 rpm, 1 % of salinity without heavy metals), 500 mg L(-1) of phenol could be completely degraded within 32 h. The high removal efficiency of phenol by the strain with significant variations of process parameters might contribute to the bioremediation of phenol-polluted environments under hypersaline or no-salt conditions.

  11. Implementasi Klien SIP Berbasis Web Menggunakan HTML5 dan Node.js

    Directory of Open Access Journals (Sweden)

    Muhammad Iqbal

    2012-09-01

    Full Text Available Perkembangan teknologi yang sangat pesat saat ini mendorong internet dan web untuk menjadi standar komunikasi yang terbaru. Dengan diperkenalkannya konsep Web 2.0 dan standar HTML5, web diharapkan dapat menjadi standar komunikasi yang universal. Di sisi lain, Rich Internet Application (RIA menjadi tren perkembangan teknologi web saat ini. Dengan teknologi tersebut, aplikasi web didesain dengan pendekatan aplikasi desktop, mengedepankan kecepatan akses, kemudahan bagi pengguna, dan keinteraktifan. Sehingga, membawa teknologi komunikasi VoIP ke teknologi RIA akan semakin memudahkan pengguna. Dengan mengimplementasikan fitur-fitur baru dari HTML5, akan dihasilkan aplikasi web yang mengikuti konsep RIA tanpa memerlukan penggunaan aplikasi pengaya pada peramban. Untuk mengetahui kemampuan dari sistem ini dilakukan tiga pengujian. Pengujian pertama adalah untuk mengetahui tingkat QoS (Quality of Service dari perangkat lunak dan yang kedua adalah survei untuk mengetahui nilai MOS (Mean Opinion Score dari perangkat lunak. Survei menghasilkan keluaran bahwa perangkat lunak memiliki skor MOS 3,8. Pengujian ketiga adalah untuk mengetahui kompatibilitas dari aplikasi-aplikasi peramban yang populer saat ini, hasil dari pengujian ini hanya peramban Google Chrome Developer Release yang mendukung aplikasi web ini secara penuh.

  12. 20 CFR 658.416 - Action on JS-related complaints.

    Science.gov (United States)

    2010-04-01

    ... agency and notify the complainant in writing of the referral. The agency shall follow-up with the... initially in a local office, and is not referred under paragraph (b), the appropriate local office official... local office has made a written request for information pursuant to § 658.412(a)(3), these time periods...

  13. *J.S., Ogeh and E. Ukodo Fu ll L eng th R esearch A rticle

    African Journals Online (AJOL)

    Profile Distribution of Physical and Chemical Properties in Soils of a Toposequence in Benin,. Rainforest of Nigeria ... years to allow organic matter and plant nutrients build up before ... soil and how human alteration to certain soil properties ...

  14. Going wireless: Fe(III) oxide reduction without pili by Geobacter sulfurreducens strain JS-1.

    Science.gov (United States)

    Smith, Jessica A; Tremblay, Pier-Luc; Shrestha, Pravin Malla; Snoeyenbos-West, Oona L; Franks, Ashley E; Nevin, Kelly P; Lovley, Derek R

    2014-07-01

    Previous studies have suggested that the conductive pili of Geobacter sulfurreducens are essential for extracellular electron transfer to Fe(III) oxides and for optimal long-range electron transport through current-producing biofilms. The KN400 strain of G. sulfurreducens reduces poorly crystalline Fe(III) oxide more rapidly than the more extensively studied DL-1 strain. Deletion of the gene encoding PilA, the structural pilin protein, in strain KN400 inhibited Fe(III) oxide reduction. However, low rates of Fe(III) reduction were detected after extended incubation (>30 days) in the presence of Fe(III) oxide. After seven consecutive transfers, the PilA-deficient strain adapted to reduce Fe(III) oxide as fast as the wild type. Microarray, whole-genome resequencing, proteomic, and gene deletion studies indicated that this adaptation was associated with the production of larger amounts of the c-type cytochrome PgcA, which was released into the culture medium. It is proposed that the extracellular cytochrome acts as an electron shuttle, promoting electron transfer from the outer cell surface to Fe(III) oxides. The adapted PilA-deficient strain competed well with the wild-type strain when both were grown together on Fe(III) oxide. However, when 50% of the culture medium was replaced with fresh medium every 3 days, the wild-type strain outcompeted the adapted strain. A possible explanation for this is that the necessity to produce additional PgcA, to replace the PgcA being continually removed, put the adapted strain at a competitive disadvantage, similar to the apparent selection against electron shuttle-producing Fe(III) reducers in many anaerobic soils and sediments. Despite increased extracellular cytochrome production, the adapted PilA-deficient strain produced low levels of current, consistent with the concept that long-range electron transport through G. sulfurreducens biofilms is more effective via pili.

  15. 20 CFR 658.415 - Transferring complaints to proper JS office.

    Science.gov (United States)

    2010-04-01

    ... letter shall be sent to the ETA Regional Office(s) with jurisdiction over the transferring and receiving.... (e) The ETA regional office with jurisdiction over the receiving State shall follow-up with...

  16. Learning Three.js the JavaScript 3D library for WebGL

    CERN Document Server

    Dirksen, Jos

    2015-01-01

    If you know JavaScript and want to start creating 3D graphics that run in any browser, this book is a great choice for you. You don't need to know anything about math or WebGL; all that you need is general knowledge of JavaScript and HTML.

  17. JS ISH-ISN-3 OPTIMAL TARGETS FOR BP CONTROL IN CKD.

    Science.gov (United States)

    Wheeler, David

    2016-09-01

    Hypertension is the most prevalent complication of chronic kidney disease (CKD). Lowering high blood pressure slows progressive loss of kidney function and may also reduce the associated risk of cardiovascular complications, a common cause of premature death in CKD patients.Current International Guidelines produced by Kidney Disease: Improving Global Outcomes (KDIGO) acknowledges that no single BP target is optimal for all CKD patients, and encourages individualization of treatment depending on age, the severity of albuminuria and comorbidities. When published in 2012, the available evidence indicated that in CKD patients without albuminuria, the target BP should be ≤140 mmHg systolic and ≤90 mmHg diastolic. However, in most patients with an albumin excretion rate of ≥30 mg/24 h (i.e., those with both micro- and macroalbuminuria), a lower target of ≤130 mmHg systolic and ≤80 mmHg diastolic was suggested. In achieving BP control, the value of lifestyle changes and the need for multiple pharmacological agents was acknowledged. Use of agents that block the renin-angiotensin-aldosterone system was recommended or suggested in all patients with an albumin excretion rate of ≥30 mg/24 h. Recommendations are almost identical in CKD patients with and without diabetes.Recent data from SPRINT (which included CKD patients) and other clinical trials has led nephrologists to ask whether targets lower than those recommend by KDIGO are appropriate and the guidelines are currently undergoing an update. Controversies remain around discontinuation of ACE/ARB in patients with stage 4-5 CKD and dual renin-angiotensin-aldosterone system blockade.

  18. Pro single page application development using Backbone.js and ASP.NET

    CERN Document Server

    Fink, Gil

    2014-01-01

    One of the most important and exciting trends in web development in recent years is the move towards single page applications, or SPAs. Instead of clicking through hyperlinks and waiting for each page to load, the user loads a site once and all the interactivity is handled fluidly by a rich JavaScript front end. If you come from a background in ASP.NET development, you'll be used to handling most interactions on the server side. Pro Single Page Application Development will guide you through your transition to this powerful new application type.The book starts in Part I by laying the groundwork

  19. Examining the Impact of Servant Leadership on Workplace Related Outcome (JS) at a Selected Private University

    Science.gov (United States)

    Guillaume, Oris

    2012-01-01

    The aim of this study was to examine the impact of Servant Leadership on a workplace related outcome (job satisfaction) at a private University in Atlanta, Georgia. The ten characteristics of Servant Leadership previously identified by Greenleaf (1977) and Spears (1998) played a significant role in job satisfaction. Other researchers (Barbuto…

  20. La Renta de la Tierra en el Pensamiento de J.S. Mill y H. George

    Directory of Open Access Journals (Sweden)

    Alberto José Figueras

    2008-12-01

    Full Text Available El año 2008 ha visto a la sociedad argentina enfrascada en un debate sobre los impuestos a las exportaciones agrícolas. Uno de los puntos centrales fue quién soportaría finalmente el costo de este tributo, su impacto sectorial, grupal y territorial. Ahora bien, cuando surgen estas controversias suele ser útil mirar hacia atrás para descubrir qué fue lo que opinaron los grandes autores del pasado en circunstancias similares, mutatis mutandi. Se revisan ideas y pensamientos de William Petty, Adam Smith, Henry George , David Ricardo y John Stuar Mill entre otros.

  1. Tranexamic Acid for Trauma Patients: A Critical Review of the Literature

    Science.gov (United States)

    2011-07-01

    pediatric urinary tract surgery,20 ruptured intracranial aneurysms ,21 oral surgery22 gynecologic surgery,23 treatment of hereditary angioneurotic edema,24...20. Ro JS, Knutrud O, Stormorken H. Antifibrinolytic treatment with tranexamic acid (AMCA) in pediatric urinary tract surgery. J Pediatr Surg...1970;5:315–320. 21. Gibbs JR, Corkill AG. Use of an anti-fibrinolytic agent (tranexamic acid) in the management of ruptured intracranial aneurysms

  2. Wald Sequential Detection with Non-Gaussian Pulsed Radar Data Using the Zakai Equation

    Science.gov (United States)

    1990-07-20

    returns, the power spectrum is also very important. It gives information as to the rate at which the radar cross section changes. Early models of the... Information (DELPHI) is under development which combines an AI engine, symbolic algebra, and numerical schemes as an "expert" system that not only...Report 8189, Naval Research Lab. 1980. [BBH83] J.S. Baras, G.L. Blankenship, and W.E. Hopkins, Jr. Existence, Uniqueness, and Asymptotic Behavoir of

  3. Characterization of Mediators of Cardiac And Renal Development in Response to Increased Prenatal Testosterone

    Science.gov (United States)

    2008-08-01

    Resistance and Hyperglycemia in the Development of Atherosclerosis. The American Journal of Cardiology 99, 6-14. Barbieri RL, Saltzman DH, Torday JS...conscious dogs . Effects on systemic and coronary hemodynamics, regional blood flows, and plasma catecholamines. J Clin Invest 69, 1321-1336. Lin CC...hemodynamics and urinary sodium excretion in dogs . Hypertension 23, 619-625. Manning RD, Jr., Hu L, Williamson TD (1994) Mechanisms involved in the

  4. Role of PTEN in the Tumor Microenvironment

    Science.gov (United States)

    2008-06-01

    mouse mammary tumors. Oncogene 24, 6870-6876. 11. Park ES, Lee JS, Woo HG, Zhan F, Shih JH, Shaughnessy JD Jr, Frederic Mushinski J. (2007...between: Pearson : p-value PTEN and ETS2-P (T72) -0.577 < 0.001 PTEN and AKT-P (S473) -0.552 < 0.001 ETS2-P (T72) and AKT-P (S473) 0.947 < 0.001 50μm

  5. Näitlejad ühes mullis, esietendus ukse ees / Hendrik Toompere jr. jr., Liisa Pulk, Mait Joorits ... [jt.] ; intervjueerinud Liisi Seil ; kommenteerinud Helle Leppik

    Index Scriptorium Estoniae

    2010-01-01

    Vestlus Eesti muusika- ja teatriakadeemia lavakunstikooli XXIV lennu tudengitega, kelle lõputöö Tom Stoppardi näidend "Arkaadia" etendub Ugala laval. Lisatud Ugala teatri kirjandustoimetaja arvamus

  6. Näitlejad ühes mullis, esietendus ukse ees / Hendrik Toompere jr. jr., Liisa Pulk, Mait Joorits ... [jt.] ; intervjueerinud Liisi Seil ; kommenteerinud Helle Leppik

    Index Scriptorium Estoniae

    2010-01-01

    Vestlus Eesti muusika- ja teatriakadeemia lavakunstikooli XXIV lennu tudengitega, kelle lõputöö Tom Stoppardi näidend "Arkaadia" etendub Ugala laval. Lisatud Ugala teatri kirjandustoimetaja arvamus

  7. 美国教育的“黑”与“白”--以教育视角纪念马丁·路德·金发表《我有一个梦想》50周年%“Black” & “White” of the Education in the United States:A Educational Perspective on the 50 th Anniversary Commemoration of Dr. Martin Luther King Jr. 's Historic Speech"I Have a Dream"

    Institute of Scientific and Technical Information of China (English)

    俞可

    2013-01-01

    To commemorate the 50th anniversary of the historic speech “I have a dream”,the questions are arising:can dreams shed light on realities,and will an era of post-racial discrimination be initiated? These questions are ur-ging to the first African-American President Barack Obama's reply after his continuance in office. On July 24,2013, trial to Racial Preference in College and University Admissions-Affirmative Action proclaimed by President Lyndon B. Johnson in 1965-was performed in the U. S. Federal Supreme Court. Holding a cardinal line on judicial combat and academic controversy of Affirmative Action as well as caused Accidental injury to Asian-American,this paper tries to re-view Dr. Martin Luther King Jr.'s heritage for the human being. Facing triple dilemma-racial discrimination or difference in social strata,social justice or atonement for history,racial diversity or multiculturalism-Affirmative Action can be self-corrected via one efficient way,an effort to gradually fade racial protection and strengthen racial integra-tion also multiculturalism. As Edge of blade to correction,education can be focused on at the first place. An Initiative names “March on Future for Education” is around the corner in America,which is being persecuted between confronta-tions of the White and Black across the history. The racial coexistence can create the American Dream.%恰逢《我有一个梦想》发表50周年,半个世纪历程能否让梦想照进现实,后种族歧视时代是否即将开启,亟待美国首位非裔总统奥巴马连任之后解答。2013年6月24日,美国联邦最高法院对高校招生的种族倾斜即约翰逊总统1965年颁布的平权政策作出判决。以平权政策的司法之战与学理之辩以及对亚裔造成的误伤为主线,本文试图以教育视角审视金馈赠全人类的这份遗产。作者认为,面对三重两难困境---即种族歧视还是阶层差异、社会公平还是历史赎罪、种族多元

  8. The Experimental Research on Application of Vegetable Oil in JS6608Vehicle Engine%植物油发动机在JS6608汽车上应用的试验研究

    Institute of Scientific and Technical Information of China (English)

    沈辉; 宗慎强; 张轶; 邱云

    2011-01-01

    柴油机直接燃用植物油燃料,存在启动困难、在怠速、低转速和小负荷等工况时燃烧排放性能差等问题。本文对原车柴油机燃料供给系统进行改进设计,应用控制单元对燃油供给系统进行控制,在启动、怠速、低转速和小负荷时给发动机供柴油,中高负荷时给发动机供植物油,实现柴油和植物油燃料的双供给。改装后整车道路试验表明,燃用植物油汽车运行可靠,动力性、经济性与原车相当,在中高负荷时燃烧和排放特性优于柴油车。%When a diesel engine fuels vegetable oil fuel directly, the engine is difficult to start and has bad combustion emissions performance at idle or low speed under low load conditions. In this paper, the diesel fuel supply system for the original vehicle is designed and is controlled with control units. When the engine starts or runs at idle, low speed or at small load, it is controlled to fuel diesel fuel but changed to burn vegetable oil fuel at medium and high load. The road tests based on a modified vehicle shows that it can run reliable with similar economy and power and better com- bustion and emission characteristics under medium and high load while fueling vegetable oil with comparison to the original vehicle.

  9. Statistical analysis of the irradiation process of various products in the industrial irradiator JS-6500; Analisis estadistico del proceso de irradiacion de productos varios en el irradiador industrial JS-6500

    Energy Technology Data Exchange (ETDEWEB)

    Naquid G, C. [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)

    2003-07-01

    In this work the methodology for the control of the irradiation service applied to disposable products of medical use, foods, medications, cosmetics and several to different dose in the Gamma Irradiation Plant, with radiation of Cobalt 60, by means of the Graphs of Quality Control by Variables. These they are used to check if the irradiation process has been carried out appropriately, or well, if the variations surpass the established limits in the one that influences some another factor. (Author)

  10. 基于HTML5+nodeJS+MongoDB构建在线图像编辑器系统

    Institute of Scientific and Technical Information of China (English)

    柯肇丰; 曾霞霞

    2015-01-01

    针对在线图像编辑器系统的功能需求,解释了系统开发使用的HTML5和JavaScript技术、以及nodeJS构建Web服务的特点与MongoDB数据存储的优势。通过介绍系统界面的设计、图层构建方法、Web后端服务实现和MongoDB数据结构,展示了系统的友好用户界面,论证了技术方案的可行性。

  11. Reload of cobalt 60 for the J S-6500 irradiator; Recarga de cobalto 60 para el irradiador JS-6500

    Energy Technology Data Exchange (ETDEWEB)

    Torres C, G.; Mayoral G, V.M

    1991-01-15

    The present work has the purpose to describe the activities of the reloads program of the industrial irradiator J S-6500, elaborated for satisfying part of the demand of services and as a first step, to guide the decision making by the part of the ININ authorities in front of a wide market of this service. (Author)

  12. JS ISH-ESH-2 UPDATE ON THE DETECTION AND FOLLOW-UP OF EARLY HYPERTENSIVE HEART DISEASE.

    Science.gov (United States)

    Rosei, Enrico Agabiti

    2016-09-01

    Current Hypertension Guidelines emphasize the importance of assessing the presence of preclinical organ damage. In fact, an extensive evaluation of organ damage may increase the number of patients classified at high CV risk and therefore strongly influence the clinical management of patients. Hypertensive heart disease remains to date the form of organ damage for which there is the greatest amount of evidence of a strong independent prognostic significance. In the presence of a chronic pressure overload, a parallel addition of sarcomers takes place with an increase in myocyte width, which in turn increases left ventricular wall thickness; myocyte hypertrophy is also associated with apoptosis, collagen deposition and ventricular fibrosis with an impairment of coronary hemodynamics as well, thus profoundly influencing functional properties of the left (and right) ventricle. The development of LVH represents a step toward the development of clinical cardiovascular diseases, such as congestive heart failure, ischemic heart disease, stroke and sudden death. Therefore, accurate assessment of cardiac anatomy and function might be of help for a prompter identification of early alterations that may predispose hypertensive patients to cardiovascular events.The Guidelines of the European Society of Hypertension and of the European Society of Cardiology include echocardiography among the recommended techniques to be considered in hypertensive patients. In fact, echocardiography is a relatively easy method, is repeatable, is specific and more sensitive measure of LVH than electrocardiography. The relationship between LV mass at baseline and incidence of cardiovascular events is continuous and independent of other cardiovascular risk factors, and has been confirmed in various subsets of patients. In addition changes in LV mass parallel the occurrence of cardiovascular fatal and non-fatal events, independently of blood pressure and other cardiovascular risk factors. Nevertheless, LV mass reproducibility represents one of the major technical limitations of echocardiography and LV mass calculation may be not reliable in patients with previous myocardial infarction or with asymmetrical hypertrophy, assuming a prolate ellipsoid shape for the left ventricle. For this reason LV mass measurement with cardiac magnetic resonance (CMR) imaging, which is indubitably more accurate and reproducible, has been proposed, but with obvious limitations related to availability and costs of the technique.Three-dimensional echocardiographic (3DEcho) imaging represents a relevant innovation in cardiovascular imaging. The development of fully sampled matrix-array transducers, together with significant improvements in hardware and software of ultrasound systems, has made possible excellent real-time imaging of the beating heart in 3D. More recent studies indicate that 3DEcho has an excellent accuracy and provides better correlations that 2-dimensional echocardiography with MRI measurements.Echocardiography may also give useful information on cardiac functional changes, including systolic and diastolic abnormalities. LV diastole may be accurately evaluated by assessment of transmitral flow velocities, mitral annular pulsed tissue Doppler imaging and left atrial volume assessment. In uncomplicated hypertensives LV systolic dysfunction, as assessed by LV shortening fraction (FS) and ejection fraction (EF), expressing endocardial fibers shortening are usually preserved or even "supernormal", while midwall FS is reduced. In the absence of major structural abnormalities, the TDI measurement of longitudinal myocardial systolic velocity has been proposed as a reliable index of myocardial performance, independent of LV preload and afterload.Compared to the conventional 2D traditional approach, 3D echo offers the opportunity for a more sophisticated assessment of LV function, by the improvement in the accuracy of the evaluation of left ventricular and left atrial volumes by eliminating the need for geometric modelling. Speckle tracking echocardiography (STE) is a relati

  13. Freedom of expression from the standpoint of J.S. Mill’s “On Liberty”

    OpenAIRE

    Rodríguez-Toubes Muñiz, Joaquín

    2010-01-01

    La primera parte del trabajo examina los argumentos a favor de la libertad de expresión que John Stuart Mill desarrolla en Sobre la libertad [On Liberty], señalando tanto los méritos como el carácter problemático de sus fundamentos utilitaristas. La segunda parte explora cómo podría aplicarse el razonamiento de Mill para resolver algunos dilemas de las sociedades pluralistas de nuestro propio tiempo, tales como encontrar un tratamiento legal adecuado para el discurso del odio o...

  14. Representations of Reductive Groups : in Honor of the 60th Birthday of David A. Vogan, Jr.

    CERN Document Server

    Trapa, Peter

    2015-01-01

    Over the last forty years, David Vogan has left an indelible imprint on the representation theory of reductive groups.  His groundbreaking ideas have lead to deep advances in the theory of real and p-adic groups, and have forged lasting connections with other subjects, including number theory, automorphic forms, algebraic geometry, and combinatorics. Representations of Reductive Groups is an outgrowth of the conference of the same name, dedicated to David Vogan on his 60th birthday, which took place at MIT on May 19-23, 2014.  This volume highlights the depth and breadth of Vogan's influence over the subjects mentioned above, and point to many exciting new directions that remain to be explored.  Notably, the first article by McGovern and Trapa offers an overview of Vogan's body of work, placing his ideas in a historical context. Contributors: Pramod N. Achar, Jeffrey D. Adams, Dan Barbasch, Manjul Bhargava, Cédric Bonnafé, Dan Ciubotaru, Meinolf Geck, William Graham, Benedict H. Gross, Xuhua He, Jing-Son...

  15. George E. Valley, Jr. Prize Talk: Exact relations for Fermi gases with large scattering length

    Science.gov (United States)

    Tan, Shina

    2011-05-01

    Ultracold two-component atomic Fermi gases near broad Feshbach resonances have both strong interactions and relatively long life times, and the strong attractions between fermions lead to remarkable properties such as superfluidity at large percentages of the Fermi temperature. The interactions can often be described by a single parameter, the two-body s-wave scattering length, which determines how the many-body wave function behaves as two atoms get much closer than the average interparticle spacing. This short-range structure of the wave function leads to a number of exact relations among energy, momentum distribution, pressure, and various high-frequency and short-wave properties. All the relations involve a quantity called contact. The exact relations point to a number of independent determinations of the contact, which have been beautifully demonstrated experimentally as well as numerically. This work was supported, in part, by DOE Grant No. DE-FG02-00ER41132.

  16. 3 CFR 8340 - Proclamation 8340 of January 15, 2009. Martin Luther King, Jr., Federal Holiday, 2009

    Science.gov (United States)

    2010-01-01

    ..., we believe it is self-evident that all men are created equal and that freedom is not a grant of government but a gift from the Author of Life. Dr. King trusted in these beliefs articulated in our founding...

  17. 36 CFR 7.21 - John D. Rockefeller, Jr. Memorial Parkway.

    Science.gov (United States)

    2010-07-01

    ... include pullouts or parking areas that are groomed or marked similarly to roadways and are adjacent to... vehicle that does not have brakes in good working order. (G) Towing persons on skis, sleds or...

  18. The "Other" Beauty of Martin Luther King, Jr.'s "Letter from Birmingham Jail."

    Science.gov (United States)

    Klein, Mia

    1981-01-01

    Submits that Martin Luther King's persuasiveness in his writings may be attributed not only to his structure, logic, and ethos, but even more to his creative, eloquent, and commanding use of the English language. Supports this argument with examples from King's "Letter from Birmingham Jail." (RL)

  19. A synopsis of the book Ecological Indicators for the Nation John Cairns, Jr

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@The U.S. Environmental Protection Agency requested the National Research Council(which is the operating arm of the U.S. National Academy of Sciences and the U.S. National Academy of Engineering) to carry out a critical scientific evaluation of indicators to monitor ecological changes from either natural or anthropogenic causes. More specifically, the National Research Council was asked to identify criteria for evaluating biological indicators, to evaluate methods of indicator development, to provide examples of ndicators that have proven useful, and to identify areas where further research is likely to yield more useful and powerful indicators. In addition, the National Research Council was to examine what aspects of environmental conditions and trends should be monitored.

  20. The Manuel Lujan, Jr. Neutron Scattering Center LANSCE experiment reports 1989 run cycle

    Energy Technology Data Exchange (ETDEWEB)

    Hyer, D.K.; DiStravolo, M.A. (comps.)

    1990-10-01

    This report contains a listing and description of experiments carried on at the LANSCE neutron scattering facility in the following areas: High Density Powder Diffraction; Neutron Powder Diffractometer, (NPD); Single Crystal Diffractometer, (SCD); Low-Q Diffractometer, (LQD); Surface Profile Analysis Reflectometer, (SPEAR); Filter Difference Spectrometer, (FDS); and Constant-Q Spectrometer.

  1. Martin Luther King, Jr., the Civil Rights Movement, and Educational Reform.

    Science.gov (United States)

    Willie, Charles Vert; Sanford, Jayminn Sulir

    1991-01-01

    Educational opportunity and civil rights are the bedrock of America's best and worst attempts to achieve pluralism. The civil rights movement shook the nation's moral fiber, weakening only after reaching the highest governing bodies. Educational reform efforts could learn much from this lesson in successful social transformation. Educational…

  2. Sigma 7 the six Mercury orbits of Walter M. Schirra, Jr

    CERN Document Server

    Burgess, Colin

    2016-01-01

    Colin Burgess offers a comprehensive yet personal look at the 1962 orbital mission of Wally Schirra aboard the spacecraft Sigma 7, the first book about this popular pioneering astronaut which explores his entire life and accomplishments. This continues the author's attempt to fully document the record of Project Mercury's pioneering early phase of the Space Age.   Schirra’s pre-NASA life is examined, as well as his training as a NASA astronaut and for his Mercury MA-8 flight. The 6-orbit flight of Sigma 7 is fully covered from its origins through to the spacecraft’s safe recovery from the ocean after a highly successful Mercury mission. Schirra’s participation on the Gemini 6 and Apollo 7 missions is also told, but in brief, and the book also relates his post-NASA life and activities through to his passing in 2007. The Mercury Seven occupy a unique spot in the history of human spaceflight, and Schirra is at last given his due as one of the contributing astronauts in this painstakingly researched...

  3. Faith 7 L. Gordon Cooper, Jr., and the final Mercury mission

    CERN Document Server

    Burgess, Colin

    2016-01-01

    This book celebrates the final spaceflight in the Mercury series, flown by NASA astronaut Gordon Cooper, who led an adventurous life in the cockpit of airplanes and spacecraft alike, and on his Mercury mission he became the last American ever to rocket into space alone. He flew in the Mercury and Gemini programs and served as head of flight crew operations in both the Apollo and Skylab programs. His final Mercury mission closed out a pivotal chapter in American spaceflight. Based on extensive research and first-person interviews, this is a complete history of the Faith 7 flight and its astronaut. Cooper later gained notoriety following the release of the movie, The Right Stuff, in which he was depicted by Dennis Quaid, but Burgess discovers there was even more drama to his story. This recounting of the final Mercury 7 flight completes Burgess's investigation of the early spaceflight program in thrilling fashion.

  4. Friendship 7 the epic orbital flight of John H. Glenn, Jr.

    CERN Document Server

    Burgess, Colin

    2015-01-01

    In this spellbinding account of an historic but troubled orbital mission, noted space historian Colin Burgess takes us back to an electrifying time in American history, when intrepid pioneers were launched atop notoriously unreliable rockets at the very dawn of human space exploration.   A nation proudly and collectively came to a standstill on the day this mission flew; a day that will be forever enshrined in American spaceflight history. On the morning of February 20, 1962, following months of frustrating delays, a Marine Corps war hero and test pilot named John Glenn finally blazed a path into orbit aboard a compact capsule named Friendship 7.   The book’s tension-filled narrative faithfully unfolds through contemporary reports and the personal recollections of astronaut John Glenn, along with those closest to the Friendship 7 story, revealing previously unknown facts behind one of America’s most ambitious and memorable pioneering space missions.

  5. Genes and schizophrenia: from a Festschrift Seminar honoring William T. Carpenter Jr, MD.

    Science.gov (United States)

    Malhotra, Anil K

    2014-03-01

    Recent data have begun to elucidate the genetic architecture of schizophrenia, as well as provide new insights into the relationships of specific genetic factors across diagnostic boundaries, with specific symptom domains, and in the prediction of antipsychotic treatment response. Not surprisingly, work conducted at the Maryland Psychiatric Research Center (MPRC), led by Dr William Carpenter, has helped to guide the thinking behind much of this work, as well as contributed valuable data toward these efforts. In this article, I will briefly summarize some of the major findings emerging from these lines of research and highlight the role of the Dr Carpenter and his colleagues at the MPRC in this area.

  6. John F. Simon, jr. / John F. jun. Simon ; interv. Tilman Baumgärtel

    Index Scriptorium Estoniae

    Simon, John F. jun.

    2006-01-01

    Ameerika kunstnikust-programmeerijast Jon F. Simon juuniorist (sünd. 1963), tema loomingust, vestlus kunstnikuga 19. 12. 1999. a. tema ateljees. J. F. Simon jun.-i teosed on tarkvara. Monitoril tekkinud kujutisi on kunstnik eksponeerinud nimetuse "Panels" all. Kunstniku joonistusprogrammist, arvutiprogrammist "Every Icon", mis asub Internetis, tööst "Combination", võrgutööst "Alter Stars" (1995-1998) ja muust

  7. The Manuel Lujan, Jr. Neutron Scattering Center, LANSCE experiment reports: 1990 Run Cycle

    Energy Technology Data Exchange (ETDEWEB)

    DiStravolo, M.A. (comp.)

    1991-10-01

    This year was the third in which LANSCE ran a formal user program. A call for proposals was issued before the scheduled run cycles, and experiment proposals were submitted by scientists from universities, industry, and other research facilities around the world. An external program advisory committee, which LANSCE shares with the Intense Pulsed Neutron Source (IPNS), Argonne National Laboratory examined the proposals and made recommendations. At LANSCE, neutrons are produced by spallation when a pulsed, 800-MeV proton beam impinges on a tungsten target. The proton pulses are provided by the Clinton P. Anderson Meson Physics Facility (LAMPF) accelerator and an associated Proton Storage Ring (PSR), which can alter the intensity, time structure, and repetition rate of the pulses. The LAMPF protons of Line D are shared between the LANSCE target and the Weapons Neutron Research facility, which results in LANSCE spectrometers being available to external users for unclassified research about 80% of each six-month LAMPF run cycle. Measurements of interest to the Los Alamos National Laboratory may also be performed and may occupy up to an additional 20% of the available beam time. These experiments are reviewed by an internal program advisory committee. One hundred thirty-four proposals were submitted for unclassified research and twelve proposals for research of a programmatic nature to the Laboratory. Our definition of beam availability is when the proton current from the PSR exceeds 50% of the planned value. The PSR ran at 65{mu}A current (average) at 20 Hz for most of 1990. All of the scheduled experiments were performed and experiments in support of the LANSCE research program were accomplished during the discretionary periods.

  8. Computational electromagnetics—retrospective and outlook in honor of Wolfgang J.R. Hoefer

    CERN Document Server

    Chen, Zhizhang

    2015-01-01

    The book will cover the past, present and future developments of field theory and computational electromagnetics. The first two chapters will give an overview of the historical developments and the present the state-of-the-art in computational electromagnetics. These two chapters will set the stage for discussing recent progress, new developments, challenges, trends, and major directions in computational electromagnetics with three main emphases:   a. Modeling of ever larger structures with multi-scale dimensions and multi-level descriptions (behavioral, circuit, network and field levels) and transient behaviours   b. Inclusions of physical effects other than electromagnetic: quantum effects, thermal effects, mechanical effects and nanoscale features   c. New developments in available computer hardware, programming paradigms (MPI, OpenMP, CUDA, and OpenCL) and the associated new modeling approaches   These are the current emerging topics in the area of computational electromagnetics and may provide reader...

  9. From philosopher to psychologist: the early career of Edwin Ray Guthrie, Jr.

    Science.gov (United States)

    Clark, David O

    2005-08-01

    Edwin R. Guthrie rose to prominence as a psychologist in the 1930s. His theoretical outlook was behavioristic. This approach came from his conviction that an objective method could be applied to a scientific treatment of mind. Prior to becoming a psychologist, he was a philosopher of mathematics. Guthrie was initiated into psychology by Stevenson Smith, from whom he learned a psychology of adjustment informed by comparative research, Columbia functionalism, and clinical psychology. Guthrie's first step into psychology was in collaboration with Smith on Chapters in General Psychology (S. Smith & E.R. Guthrie, 1921). To synthesize their own unique position on learning from the contemporary theory and research, they used the principle of association. This articles focuses on Guthrie's origin and his development into a learning theorist.

  10. Attempts to culture the parasitic stage of Dermatobia hominis (L. Jr.) in vitro (Diptera: Cuterebridae).

    Science.gov (United States)

    Zeledón, R; Silva, S

    1987-10-01

    Dermatobia hominis larvae were cultured in a semidefined liquid medium. First-instar larvae (L1) grew well up to 44 days; 29.1% molted in a mean period of 8.62 days. Two larvae reached the third instar but lived only 1 and 18 days, respectively, after the second molt. The increase in size, measured in 4 larvae, was about 10-fold. Second- and third-instar larvae, obtained from the skin of cattle, survived and grew in the medium for up to 2 mo; 39.0% of the L2 molted while 77.3% of the L3 pupated, and some produced flies when transferred to sand after 14.84 +/- 10.08 days in the culture medium. Some maturation factor, obtained from the skin, may be necessary for the larvae to grow satisfactorily and to complete the full parasitic cycle in vitro.

  11. Study of Calamus occidentalis J.R. Witono & J. Dransf. Species Commercial Values and Possible Utilization

    Directory of Open Access Journals (Sweden)

    JASNI

    2004-07-01

    Full Text Available The selection of appropriate rattan for a certain use must be based on adequate information about its potency, anatomical structure, and chemical properties. Standards methods of inventory development by Curtis method was used to obtain data on its density and frequency. To know the anatomical structure of preparation were made according to Schultze method and microtome preparation according to Staining Paraffin Section with Safranin. While to know the chemical component of rattan stem the analyzed by Standard Industry Indonesia procedures. Calamus occidentalis is one among other Java rattan species which its distribution is limited in the area of Ujung Kulon National Park, West Java. C. occidentalis may be utilized for various purposes based on the following characteristics: species density of 21 cane/ha; and anatomical structure: fiber length of 2204 m, fiber-wall thickness of 4.26 m, vascular bundle diameter of 812.5 m, metaxylem diameter of 293.75 m, proxylem diameter of 43.5 m, and phloem diameter of 37.5 m. Its chemical components are cellulose (49.95%, lignin (22.39%, and air-dry moisture (12.27%. Based on the above information, C. occidentalis rattan species possibly can be used as an alternative substitute of Calamus manan, an endangered rattan species, because several properties of C. occidentalis has similar with that of C. manan.

  12. The tadpole of Scinax melanodactylus (Lourenço, Luna & Pombal Jr, 2014) (Amphibia, Anura, Hylidae).

    Science.gov (United States)

    Abreu, Rafael Oliveira De; Napoli, Marcelo Felgueiras; Trevisan, Camila Costa; Camardelli, Milena; Dória, Thais Andrade Ferreira; Silva, Lucas Menezes

    2015-07-06

    Scinax melanodactylus is a small treefrog distributed within the Tropical Atlantic morphoclimatic domain (see Ab'Sáber 1977 for South American morphoclimatic domains), from northern Espírito Santo state to Sergipe state in Brazil (Lourenço et al. 2014). The species is usually found inhabiting herbaceous and shrubby xerophytic vegetation (e.g. terrestrial tank-bromeliads) from sandy plains of beach ridges known in Brazil as Restingas (see Rocha et al. 2007 for a Restinga definition), and also the edge of forest areas with temporary ponds and/or permanent lakes and streams near these environments (Bastazini et al. 2007, as Scinax agilis; Lourenço et al. 2014). Scinax melanodactylus is currently placed in the S. catharinae species group (Lourenço et al. 2014), which in turn is included in the S. catharinae clade (sensu Faivovich et al. 2005). The S. catharinae clade is currently comprised of 46 species, 33 placed in the catharinae group and 13 in the perpusillus group (Faivovich et al. 2010, Silva & Alves-da-Silva 2011, Lourenço et al. 2014, Frost 2015). From these, 32 species have tadpoles with external morphology and oral disc formerly described. Here, we describe the external morphology, oral disc and color patterns of the previously unknown tadpole of S. melanodactylus.

  13. 76 FR 71048 - Sixth Annual Philip S. Chen, Jr. Distinguished Lecture on Innovation and Technology Transfer

    Science.gov (United States)

    2011-11-16

    ... Innovation and Technology Transfer AGENCY: National Institutes of Health, Public Health Service, HHS. ACTION....D. Distinguished Lecture on Innovation and Technology Transfer. DATES: Friday, December 9, 2011, at... Recombinant Immunotoxins: From Technology Transfer to the Patient.'' Dr. Pastan is an NIH Distinguished...

  14. Duplik fra den højrøvede og glemsomme forsker

    DEFF Research Database (Denmark)

    Christensen, Peter Holdt

    2015-01-01

    Det er godt med diskussion om vores fælles arbejdsplads, men bør vi ikke først og fremmest overveje om flere timer i undervisningslokalet er den rigtige måde at øge kvaliteten i undervisningen på?......Det er godt med diskussion om vores fælles arbejdsplads, men bør vi ikke først og fremmest overveje om flere timer i undervisningslokalet er den rigtige måde at øge kvaliteten i undervisningen på?...

  15. Vil! Elmar Õun jr 2010. aasta visiidid Tallinna ja Keilasse / Tõnu Tooming

    Index Scriptorium Estoniae

    Tooming, Tõnu

    2010-01-01

    Korporatsiooni Fraternitas Liviensis Rootsis elava kaasvenna külaskäigust Eestisse. Keila linna päevadel anti Elmar Õunale üle linna teenetemärk sõprussuhete loomise ja hoidmise eest Keila ja Nacka linna vahel

  16. The Manuel Lujan, Jr. Neutron Scattering Center (LANSCE) experiment reports 1992 run cycle. Progress report

    Energy Technology Data Exchange (ETDEWEB)

    DiStravolo, M.A. [comp.

    1993-09-01

    This year was the fifth in which LANSCE ran a formal user program. A call for proposals was issued before the scheduled run cycles, and experiment proposals were submitted by scientists from universities, industry, and other research facilities around the world. An external program advisory committee, which LANSCE shares with the Intense Pulsed Neutron Source (IPNS), Argonne National Laboratory, examined the proposals and made recommendations. At LANSCE, neutrons are produced by spallation when a pulsed, 800-MeV proton beam impinges on a tungsten target. The proton pulses are provided by the Clinton P. Anderson Meson Physics Facility (LAMPF) accelerator and an associated Proton Storage Ring (PSR), which can alter the intensity, time structure, and repetition rate of the pulses. The LAMPF protons of Line D are shared between the LANSCE target and the Weapons Neutron Research (WNR) facility, which results in LANSCE spectrometers being available to external users for unclassified research about 80% of each annual LAMPF run cycle. Measurements of interest to the Los Alamos National Laboratory may also be performed and may occupy up to an additional 20% of the available beam time. These experiments are reviewed by an internal program advisory committee. One hundred sixty-seven proposals were submitted for unclassified research and twelve proposals for research of a programmatic interest to the Laboratory; six experiments in support of the LANSCE research program were accomplished during the discretionary periods. Oversubscription for instrument beam time by a factor of three was evident with 839 total days requested and only 371 available for allocation.

  17. I Have a Dream: Martin Luther King, Jr. Handbook of Activities.

    Science.gov (United States)

    Duff, Ogle Burks, Ed.; Bowman, Suzanne H., Ed.

    This handbook is designed by teachers for teachers to share ideas and activities for celebrating the Martin Luther King holiday, as well as to teach students about other famous black leaders throughout the school year. The lesson plans and activities are presented for use in K-12 classrooms. Each lesson plan has a designated subject area, goals,…

  18. John F. Simon, jr. / John F. jun. Simon ; interv. Tilman Baumgärtel

    Index Scriptorium Estoniae

    Simon, John F. jun.

    2006-01-01

    Ameerika kunstnikust-programmeerijast Jon F. Simon juuniorist (sünd. 1963), tema loomingust, vestlus kunstnikuga 19. 12. 1999. a. tema ateljees. J. F. Simon jun.-i teosed on tarkvara. Monitoril tekkinud kujutisi on kunstnik eksponeerinud nimetuse "Panels" all. Kunstniku joonistusprogrammist, arvutiprogrammist "Every Icon", mis asub Internetis, tööst "Combination", võrgutööst "Alter Stars" (1995-1998) ja muust

  19. The Leadership Development of Dwight D. Eisenhower and George S. Patton Jr

    Science.gov (United States)

    2009-06-12

    shots were fired, Patton found Carranza and killed him and two of his men. 87 Pershing authorized a press release of the story to the newspapers...first lieutenant. He gained fame by killing Carranza and assisting with the capture of Lujan. He also had experiences with the Army‘s latest

  20. Great Expectations: Brigadier General Haywood S. Hansell, Jr.and the XXI Bomber Command

    Science.gov (United States)

    2015-07-01

    Command and Staff College (Military Operational Art and Science) in 2013. v ACKNOWLEDGEMENTS I would like to acknowledge several people...Japanese strength.”7 Radar bombing was a valuable secondary technique, but the necessary radar maps were nonexistent until aerial photography commenced...Emmett O’Donnell, Commander, 73rd Bombardment Wing, letter, 19 August 1944, O’Donnell Collection (MS43/B11/F9). 8 The first photography missions over

  1. Book review of Electrophysiological Recording Techniques, edited by Robert P Vertes and Robert W Stackman, Jr

    Directory of Open Access Journals (Sweden)

    Kolev Vasil

    2011-07-01

    Full Text Available Abstract The review presents the newly published book "Electrophysiological Recording Techniques" by Humana Press. This is an important collection of articles devoted to an issue that has gained increasing attention in modern neuroscience research - electrophysiological recording techniques. The present book is a timely update of methods spanning from single cell recordings to local field potentials, cortical, and scalp EEG recordings. The book presents the progressive development of electrophysiological recording methods by including both existing and new advanced technologies. Theoretical considerations on important issues like current source density analysis, local field potential and signal generation are also in focus. In most of the chapters, methods are illustrated with specific experimental results and are discussed towards future developments and applications. Chapters can be read independently because each chapter appears with its own theoretical background, literature survey and specific methodology. The book can be of interest to a broader audience willing to look at the contemporary state of development of electrophysiological methods. Also, it can be of special interest to scientists with high expertise working in the field of neuroscience and behavior.

  2. 77 FR 57116 - Cleveland J. Enmon, Jr., M.D.; Decision and Order

    Science.gov (United States)

    2012-09-17

    ... lower back pain stemming from a car accident in which she was ejected from the vehicle. . Despite this... medications and lifestyle changes, diet, exercise, heat applications, physical therapy, possibly...

  3. Martin Luther King, Jr.'s "Beloved Community" Ideal and the Apartheid System in South Africa.

    Science.gov (United States)

    Baldwin, Lewis V.

    1986-01-01

    King's comments and opinions on the following aspects of South African apartheid are presented: (1) similarities to and differences from America's racist system; (2) the role of western countries and their pressure; (3) the role of black Americans; (4) the role of multi-racial coalitions; and (5) the role of religious groups. (PS)

  4. PERJUANGAN MEMERDEKAKAN KAUM TERTINDAS: BELAJAR DARI MARTIN LUTHER KING, JR DAN MALCOLM X

    OpenAIRE

    Zuly Qodir

    2011-01-01

    Amerika, negara adi daya yang mengklaim paling demokratis ternyata memiliki beberapa keburukan substansial. Bukan saja secara konseptual, tetapi dalam praktik politik, Amerika ternyata menyimpan persoalan sangat serius. Sayangnya jarang dikemukakan pada publik oleh pemerintahan Amerika maupun para pengamat dan sekaligus pemuka Negeri Paman Sam tersebut. Kebobrokan Amerika tertutup dengan kampanye yang sangat besar dan sistematik tentang kehebatan Amerika memba...

  5. Notes on Pemphis acidula J.R. Forst. & G. Forst. (Myrtales: Lythraceae from Andaman Islands, India

    Directory of Open Access Journals (Sweden)

    M.P. Goutham-Bharathi

    2015-06-01

    Full Text Available Pemphis acidula Forst. (Lythraceae has been reported herein with locality data after a lapse of 91 years from Andaman Islands. This re-discovery is significant as P. acidula has not been added to the mangrove flora of India in many important national and international status reports. This species is characterized by its narrowly elliptic to lanceolate leaves that are densely covered with silky hairs on both surfaces, crumpled white petals, capsule with circumscissile dehiscence and winged seeds. Further, new morphological discoveries viz., tetramerous and pentamerous flowers were reported in the present study in contrast to the perfect hexamerous flowers reported elsewhere. Since P. acidula is sparsely distributed, location-specific conservation strategies should be adapted in order to prevent its local extinction from the Islands. In addition, exploratory surveys are imperative particularly in calcareous rocky habitats for authenticating the wider distribution of such rare species. 

  6. Social Justice in Hard Times: Celebrating the Vision of Dr. Martin Luther King, Jr.

    Science.gov (United States)

    Nieto, Sonia

    2005-01-01

    It is important to remember that one's presence "can" create a clamor, a person's action "does" make a difference. The author is reminded of this fact whenever he thinks about a poem by Angel Nieto. Similarly, individuals need to be reminded of this fact more than ever before because these are hard times for social justice. As individuals…

  7. Letters of Second Lieutenant Charles Wesley Chapman, Jr. December 19, 1894 - May 3, 1918

    Science.gov (United States)

    2016-04-01

    Ages are in history . Tonight most of the ten Americans have letters—some boxes—from home, consequently the meal tonight was unusually animated . In a...largest single appropriation in American history to that time: $640 million to build a mighty air force. Headlines such as “Greatest of Aerial Fleets to...arm lacked the right experience and technology. For the most part, the American aircraft industry failed to meet the challenge (a scandal, given

  8. Notes on Pemphis acidula J.R. Forst. & G. Forst. (Myrtales: Lythraceae from Andaman Islands, India

    Directory of Open Access Journals (Sweden)

    M.P. Goutham-Bharathi

    2015-06-01

    Full Text Available Pemphis acidula Forst. (Lythraceae has been reported herein with locality data after a lapse of 91 years from Andaman Islands. This re-discovery is significant as P. acidula has not been added to the mangrove flora of India in many important national and international status reports. This species is characterized by its narrowly elliptic to lanceolate leaves that are densely covered with silky hairs on both surfaces, crumpled white petals, capsule with circumscissile dehiscence and winged seeds. Further, new morphological discoveries viz., tetramerous and pentamerous flowers were reported in the present study in contrast to the perfect hexamerous flowers reported elsewhere. Since P. acidula is sparsely distributed, location-specific conservation strategies should be adapted in order to prevent its local extinction from the Islands. In addition, exploratory surveys are imperative particularly in calcareous rocky habitats for authenticating the wider distribution of such rare species. 

  9. A Child Development Point of View: Excerpts from the Writings of James L. Hymes, Jr.

    Science.gov (United States)

    Hymes, James L., Jr.

    1998-01-01

    Discusses concerns of child development as a field of study, meeting a child's educational needs in developmentally appropriate ways, and encouraging children's growth by meeting their needs through basic decency. Notes that children's development proceeds most efficiently when teachers and caregivers observe children's natural development,…

  10. The Rhetoric of Martin Luther King, Jr.: Letter from Birmingham Jail

    Science.gov (United States)

    Mott, Wesley T.

    1975-01-01

    Argues that the success of 'The Letter' can be attributed to the confluence of three distinct rhetorical traits: King's heritage of the highly emotional Negro preaching tradition, his shrewd sense of political timing and polemical skill, and his conscious literary ability, and notes that 'The Letter' is one of the most frequently collected items…

  11. Disease: H00930 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available heterogeneous. One form is associated with abnormal cellular cholesterol efflux caused by heterozygous muta...tions at the ABCA1 gene. Other forms are primary hypoalphalipoproteinemia caused ...ABCA1 [HSA:19] [KO:K05641] APOA1 [HSA:335] [KO:K08757] Tangier disease [DS:H00159] is also cause..., Maeda N, Parks JS Targeted inactivation of hepatic Abca1 causes profound hypoal...ucher B, Rondeau C, Genest J Jr Decreased cellular cholesterol efflux is a common cause

  12. Crack Growth and Stress Intensity Prediction Techniques. Delivery Order 0027-1: Mixed Mode Failure Criteria

    Science.gov (United States)

    2006-03-01

    285- 301 (2001). 50. Hinton E and Campbell JS, "Local and Global Smoothing of Discontinuous Finite Element Functions Using a Least Squares Method...by Plastic Deformation,” Acta Metallurgica, 27,1-15(1979). 61. Cox, T. B. and Low, J.R., “An Investigation of the Plastic Fracture of AISI 4340 and...under Tension-Torsion Loading", International Journal of Fracture, 109, 285- 301 (2001). 6. Helm, J.D. Helm, M.A. Sutton and M.L. Boone

  13. ANISOTROPIC CHARACTERISTICS OF DEMAGNETIZATION CURVE FOR NANOCRYSTALLINE Nd-Fe-B MAGNET CALCULATED BY MICROMAGNETICS

    Institute of Scientific and Technical Information of China (English)

    金汉民; 王学凤; 赵素芬; 闫羽

    2001-01-01

    The demagnetization curves for nanocrystalline Nd-Fe-B magnets of a stoichiometric composition were calculated by making use of the finite element technique of micromagnetics. The curve, especially iHc, varies in a wide range with the direction of applied field if the grain number N is taken to be small. With the increase of N, the range becomes smaller and the average of iHc decreases and approaches a limit iHc(N = ∞). iHc for finite N is larger than, or at least equal to, iHc(N= o∞). Jr/Js is weakly affected by N and the field direction. Jr/Js(N = oo) decreases with the increase of grain size L. These are larger than the experimental values for the Nd-rich Nd2.33Fe14B1.06Si0.21 magnets by ~0.05. iHc(N = ∞) increases with the increase of L, and is close to or somewhat smaller than the experimental values of the Nd-rich magnet, as would be expected. In contrast, the curve calculated for the non-interacting grain system (Stoner-Wohlfarth model) of N 30 depends neither on the field direction nor on N.

  14. VizieR Online Data Catalog: Kepler-80 transit timing observations (MacDonald+, 2016)

    Science.gov (United States)

    MacDonald, M. G.; Ragozzine, D.; Fabrycky, D. C.; Ford, E. B.; Holman, M. J.; Isaacson, H. T.; Lissauer, J. J.; Lopez, E. D.; Mazeh, T.; Rogers, L.; Rowe, J. F.; Steffen, J. H.; Torres, G.

    2017-05-01

    Kepler-80 was observed photometrically by the Kepler Space Telescope. We had access to several sets of Transit Timing (TT) measurements, including the publicly available data from Rowe & Thompson (arXiv:1504.00707) and Mazeh et al. 2013 (Cat. J/ApJS/208/16). We also had the updated long-cadence TT estimates from the Mazeh group (Holczer et al. 2016, Cat. J/ApJS/225/9) and short-cadence TT data from both co-authors JR and DF. These were all measured using similar methods (see Mazeh et al. 2013, Cat. J/ApJS/208/16) and had no major differences. Spectra were taken of Kepler-80 by Keck and McDonald Observatories, and these spectra and preliminary interpretations are available on the Kepler Community Follow-up Observing Program (CFOP) website (https://cfop.ipac.caltech.edu). We acquired an 1800s high-resolution spectrum with the Keck I telescope and the High Resolution Echelle Spectrometer (HIRES) on 2011 July 20. The standard California Planet Search setup and data reduction of HIRES was used, resulting in a S/N of 35 at 5500Å. The C2 decker, with dimensions of 0.87''*14'', was used to allow a resolution of ~60000 and sky subtraction. (5 data files).

  15. Desenvolvimento pós-embrionário do intestino médio de Dermatobia hominis (Linnaeus Jr. (Diptera, Cuterebridae Post-embryonic development of Dermatobia hominis (Linnaeus Jr. (Diptera, Cuterebridae midgut

    Directory of Open Access Journals (Sweden)

    Edy de Lello

    2001-03-01

    Full Text Available Dermatobia hominis (Linnaeus, 1781 midgut is internally lined by an epithelium of polytenic cells, some low others prismatic with well developed brush border. Their apical portion are enlarged by secretory vesicles, forming button-like structures that are pinched off to the lumen, some accompained by the nucleus characterizing apocrine and holocrine secretions. This epithelium is gradually renewed by small, non polytenic regenerative cells, found scattered at its basal portion. At the end of the third instar the metamorphosis begins. The epithelial cells present signs of degeneration and at the first day of pupation the regenerative cells increase in number. By the 5th day of pupation these regenerative cells, besides being increased in number, differentiate themselves into two layers: one similar to the dense conective tissue that sustainning the larval epithelium is pinched off to the midgut lumen forming the "yellow bodies"; the other, develops right under it as the imaginal epitelium. The disorganized muscles bundles of the midgut wall, are invaded by phagocytes. At the end of pupation the midgut has a low prismatic epithelium with brush-border. In the adult, the torax portion of the midgut has prismatic homogeneously basophilic epithelium while in the abdominal portion the epithelium is made of high prismatic cells full of small vacuoles. The larval midgut epithelium suffers programmed cell death non compatible with apoptose. During the metamorphosis the midgut lenght diminishes from 31mm in the larva to 14mm in the adult.

  16. Remarks of Joseph A. Califano, Jr., Secretary of Health, Education, and Welfare before the 1977 NRA National Conference

    Science.gov (United States)

    Califano, Joseph A., Jr.

    1977-01-01

    Focuses on (1) some steps that President Carter and the Department of Health, Education, and Welfare (DHEW) have taken to serve handicapped Americans, (2) new efforts that are underway in DHEW, such as closed captioning for the deaf, and (3) future effectiveness of rehabilitation programs in light of inflated expenses for health and hospital care.…

  17. Recent advances and future directions in causality, prediction, and specification analysis essays in honor of Halbert L. White Jr.

    CERN Document Server

    Chen, Xiaohong

    2014-01-01

    Written by leading experts in the field, this volume presents cutting-edge results on specification and estimation of economic models. Advances in asymptotic approximation theory are discussed, as well as the use of various theoretical tools for technique development.

  18. Analisis Komponen Senyawa Kimia Dan Uji Aktivitas Antibakteri Minyak Atsiri Daun Zodia (Euodia Hortensis J.R & G. Forst)

    OpenAIRE

    2015-01-01

    Zodia leaf essential oil (Euodia hortensis J.G & G.Forst) was isolated by using a method hidrodestillation Sthal. Leaves zodia in destillation for ± 4-5 hours resulting essential oil amount 0,60%. Chemical components of the leaf essential oil zodia analyzed using GC-MS showed there were 16 compounds and components adapted to the standar library wiley and library nist only 10 main compounds is Menthofuran (40,54%), 4(5H)-Benzofuranone (20,70), Limonene (18,31%), 1(7),8(10)-p-Metadien-9-ol (8,5...

  19. Religion and fight for social justice in the american political thought: richard rorty, john rawls, and martin luther king, jr.

    OpenAIRE

    Voparil, Christopher J.

    2013-01-01

    John Rawls's "political" conception remains our most influential notion of justice designed to respect the irreducible and irreconcilable diversity of moral, philosophical, and religious doctrines characteristic of a pluralistic democratic culture. While we know from recent posthumous publications of Rawls's deep understanding of religion's ultimate importance, this conception seems to exclude a fundamental dimension of the most important struggles for social justice, like the role of the bla...

  20. "Some People Even Died": Martin Luther King, Jr, the Civil Rights Movement and the Politics of Remembrance in Elementary Classrooms

    Science.gov (United States)

    Wills, John S.

    2005-01-01

    This article examines the interpretive practices and cultural texts that shape what teachers and students remember and forget during the annual observance of the King holiday in two second-grade classrooms. Drawing on data from an ethnographic case study of the curriculum in use and theory and research on collective memory, the author analyzes the…

  1. Martin Luther King Jr.'s "I Have a Dream" in Context: Ceremonial Protest and African American Jeremiad.

    Science.gov (United States)

    Vander Lei, Elizabeth; Miller, Keith D.

    1999-01-01

    Discusses how "I Have a Dream" is the product of African-American rhetorical traditions of ceremonial protest and jeremiad speech-making, rituals that had crystallized long before King was born. Describes the peaceful essences of the March on Washington and how it was a "Ceremonial Protest." Considers the historical use of…

  2. The mining, agricultural and construction equipment protocol to the Cape Town Convention project: The current status/ Charles W. Mooney Jr.

    Index Scriptorium Estoniae

    Mooney Jr., Charles

    2016-01-01

    Liikurseadmetega seotud rahvusvaheliste tagatiste konventsioon (Kaplinna konventsioon, 2001) ja protokoll õhusõidukite seadmetele eriomastest küsimustest ja mõjust põllumajandusele ning ehitusele. UNIDROIT = International Institute for the Unification of Private Law

  3. Una nueva metodología para la evaluación de la curva J-R

    Directory of Open Access Journals (Sweden)

    Donoso, J. R.

    2005-12-01

    Full Text Available A new methodology for the construction of J-R curves for ductile materials, based upon the analytical integration of the P-v relation, is presented. This method is based on the "Common" and "Concise" "Formats", and on a postulated crack growth law, that relates the amount of stable crack growth with plastic displacement. The model developed, denoted as C&C, reproduces quite well the experimentally obtained P-ν, Δa-νand J-Δa curves. The results suggest that the amount of stable crack growth in a ductile material follows a power law behavior in its dependence with plastic displacement. This methodology may be used to evaluate instability conditions, through the adequate analytical treatment of the P-ν and J-Δarelations.

    Se presenta una nueva metodología de construcción de la curva J-R para materiales dúctiles, obtenida por integración analítica de la relación P-v. Esta metodología está basada en los "Formatos" "Común" y "Conciso", y en el postulado de una ley de crecimiento de grieta, que relaciona el monto de avance estable con el desplazamiento plástico. El modelo desarrollado, denominado C&C, reproduce muy bien las curvas obtenidas experimentalmente de los tipos P-ν, Δa-ν y J-Δa. Los resultados generados permiten sugerir que el crecimiento estable de grieta en un material dúctil obedece una relación de tipo potencial en su dependencia con el desplazamiento plástico. Esta metodología, puede utilizarse para evaluar las condiciones de inestabilidad, mediante el adecuado tratamiento analítico de las relaciones P-ν y J-Δa.

  4. General George S. Patton, Jr: Master of Operational Battle Command. What Lasting Battle Command Lessons Can We Learn From Him?

    Science.gov (United States)

    2007-11-02

    each soldier receive one pair of dry socks per day. It was also during this time that the Third Army had as many non battle casualties due to the...same perspective on his units in combat if he does not see them. General Patton was notorious for slipping into subordinate headquarters and simply

  5. Images of the Recent Past: Readings in Historical Archaeology, edited by Charles E. Orser Jr. Altamira Press, Walnut Creek, 1996

    Directory of Open Access Journals (Sweden)

    Susan Malin-Boyce

    1998-05-01

    Full Text Available When searching for a reader in historical archaeology this volume is the place to start. Charles Orser has collected some fine examples of historical archaeology for this publication that spans over a decade of research. They introduc emethod, theory, the underlying philosophical issues behind theory, and the appli­cation of all of these to archaeological data sets of the historic period. The volume is organized thematically into six sections each with its own introduction. In all there are twenty chapters and Orser's introduction to the volume. The first and final sections offer perspectives on the state of historical archaeology as an endeavor, both in the United States and abroad. The remainder of the volume presents case studies in several categories. Though these categories seem somewhat arbitrary given the breadth of the material covered, they do serve to juxtapose articles facilitating an appreciation for the complementarity of varied approaches.

  6. The mining, agricultural and construction equipment protocol to the Cape Town Convention project: The current status/ Charles W. Mooney Jr.

    Index Scriptorium Estoniae

    Mooney Jr., Charles

    2016-01-01

    Liikurseadmetega seotud rahvusvaheliste tagatiste konventsioon (Kaplinna konventsioon, 2001) ja protokoll õhusõidukite seadmetele eriomastest küsimustest ja mõjust põllumajandusele ning ehitusele. UNIDROIT = International Institute for the Unification of Private Law

  7. Martin Luther King Jr. and Cesar E. Chavez: Legacies of Leadership and Inspiration for Today's Civic Education. Issue Paper

    Science.gov (United States)

    Welch, Anthony; Rodriguez, Julie Chavez

    2005-01-01

    This year, Americans celebrate and reflect on the 40th anniversary of the 1965 Voting Rights Act that secured the right to vote for millions of disenfranchised African Americans, as well as the 50th anniversary of the bus boycott in Montgomery, Alabama, where Rosa Parks stood up for justice by sitting down on a bus, thus catalyzing the Civil …

  8. 忆马丁·路德·金博士%Rev. Dr. Martin Luther King, Jr.

    Institute of Scientific and Technical Information of China (English)

    唐纳德·拉姆斯菲尔德; 刘鹏; 朱一童

    2006-01-01

    人们常说美国是世界上最早实现民主的国家。从某种意义上讲这是事实。在近代,公民应该在管理自己政府事务中有重要发言权这样一种大胆的理念最先是在我们国家得以付诸实践的。

  9. 78 FR 44524 - In the Matter of: Orville L. Parker, Jr., 2647 W. Walton Street, Chicago, IL 60622, Respondent...

    Science.gov (United States)

    2013-07-24

    ... by Failing To File a Shipper's Export Declaration or Automated Export Systems Record On or about... (``SED'') or Automated Export System (``AES'') record with the U.S. Government. Pursuant to Section 758.1... 766.3 of the Export Administration Regulations (the ``Regulations''),\\1\\ and Section 13(c) of...

  10. "EFFECTS OF FLOW INTENSITY, OBSTACLE ALIGNMENT AND CROSS-SECTION GEOMETRY ON SCOUR AT BRIDGE ABUTMENTS" CARDOSO, A.H., SANTOS, J.S. and ROCA, M.

    Institute of Scientific and Technical Information of China (English)

    Bruce W. MELVILLE

    2002-01-01

    The authors present new measurements of maximum (equilibrium) local scour depth at bridge abutments, the new data being analysed in terms of the multiplying factors given in Melville (1992,1997) and Melville and Coleman (2000). The design method presented in these publications is referred to here as the University of Auckland (UoA) Method. The authors' data apply to the following factors:∏f (flow intensity), ∏θ (abutment alignment) and ∏g (approach channel geometry).

  11. Asynchronous and Non-blocking I/O of NodeJS%NodeJS的异步非阻塞I/O研究

    Institute of Scientific and Technical Information of China (English)

    许会元; 何利力

    2015-01-01

    NodeJS算得上是如今最火热的技术了,它是一个服务器端JavaScript执行环境,它将改变服务器应该如何工作的概念.它的目标是帮助程序员构建高度可伸缩的应用程序,编写能够处理数万条并发请求的连接代码.除了Web应用外,NodeJS也被应用在许多方面,这些项目涉及到应用程序监控、媒体流、远程控制、桌面和移动应用等等.主要内容包括NodeJS的简单介绍以及对其核心特性异步I/O的研究.

  12. Study of Express Framework's Routing Mechanism in Node.js%Node.js中Express框架路由机制的研究

    Institute of Scientific and Technical Information of China (English)

    程桂花; 沈炜; 何松林; 张珂杰

    2016-01-01

    Express作为Node.js的一个Web开发框架已经被工程师们所熟知.使用该框架的各种特性可以更加方便、快速地开发出一个比较完整的Web应用程序.和其他Web开发框架一样,Express隐藏了代码背后的繁琐,开发者可以将工作的重心放在编写代码上,但Express更为优秀的是为开发者们提供了一种路由机制,分析了Express路由机制的特性,并研究该路由机制在程序开发中的应用方式.

  13. 基于Node.js,Socket.io和jQuery Mobile的周界入侵检测报警控制系统设计

    Institute of Scientific and Technical Information of China (English)

    尹延宁; 刘太君; 叶焱

    2015-01-01

    为解决当前周界入侵检测报警控制系统同底层硬件耦合紧密,硬件控制器功能单一,智能化不足的问题,提出了一种基于云架构和物联网的整体设计方案.依托于云架构,以安卓系统作为硬件控制器,利用web服务器Node.js结合即时通信技术Socket.io实现报警信息的即时推送,通过NoSQL数据库MongoDB进行相关数据储存,前端采用jQuery Moble框架实现控制与显示功能.详细阐述了系统的架构、功能和设计方案,为建设新型周界入侵检测报警控制和显示系统提供了新的思路与方向.

  14. Based on Node.js to Constructthe High Concurrent WMTS Service%基于Node.js构建高并发WMTS服务

    Institute of Scientific and Technical Information of China (English)

    马秉斌; 牛艳霞

    2015-01-01

    通过对WMTS服务功能接口的分析,基于Node.js平台非阻塞式I/O、事件驱动等高并发特性,实现了高并发响应的地图切片服务,并利用Openlayers实现了地图服务的调用和展示.

  15. Geology of the Yucca Mountain Region, Chapter in Stuckless, J.S., ED., Yucca Mountain, Nevada - A Proposed Geologic Repository for High-Level Radioactive Waste

    Energy Technology Data Exchange (ETDEWEB)

    J.S. Stuckless; D. O' Leary

    2006-09-25

    Yucca Mountain has been proposed as the site for the Nation's first geologic repository for high-level radioactive waste. This chapter provides the geologic framework for the Yucca Mountain region. The regional geologic units range in age from late Precambrian through Holocene, and these are described briefly. Yucca Mountain is composed dominantly of pyroclastic units that range in age from 11.4 to 15.2 Ma. The proposed repository would be constructed within the Topopah Spring Tuff, which is the lower of two major zoned and welded ash-flow tuffs within the Paintbrush Group. The two welded tuffs are separated by the partly to nonwelded Pah Canyon Tuff and Yucca Mountain Tuff, which together figure prominently in the hydrology of the unsaturated zone. The Quaternary deposits are primarily alluvial sediments with minor basaltic cinder cones and flows. Both have been studied extensively because of their importance in predicting the long-term performance of the proposed repository. Basaltic volcanism began about 10 Ma and continued as recently as about 80 ka with the eruption of cones and flows at Lathrop Wells, approximately 10 km south-southwest of Yucca Mountain. Geologic structure in the Yucca Mountain region is complex. During the latest Paleozoic and Mesozoic, strong compressional forces caused tight folding and thrust faulting. The present regional setting is one of extension, and normal faulting has been active from the Miocene through to the present. There are three major local tectonic domains: (1) Basin and Range, (2) Walker Lane, and (3) Inyo-Mono. Each domain has an effect on the stability of Yucca Mountain.

  16. Uudised : Õhtusöök ̉ la J.S. Bach. Peeter Lilje mälestusfondist. Nana Mouskouri Tallinnas / Kerle Arula

    Index Scriptorium Estoniae

    Arula, Kerle

    2000-01-01

    19. nov. restoranis Balthasar toimuvast õhtusöögist koos Bachi muusikaga. P. Lilje nimelisest fondist interpretatsioonikunsti jäädvustamiseks. 22. nov. annab Kaarli kirikus heategevuskontserdi N. Mouskouri

  17. Mājsaimniecību Ietekme uz Klimatu Latvijā: Oglekļa Pēdas Rādītājs

    Science.gov (United States)

    Brizga, J.; Kudreņickis, I.

    2009-01-01

    People more and more recognize climate change as one of the main environmental problems and the term `carbon footprint' (CF) has become popular and is now in widespread use. In this paper, the CF concept has been applied to analyse average per capita household Greenhouse Gas (GHG) emissions in Latvia. We explore household CF in housing (heating and electricity consumption), transport, food and goods and service sectors, which are the main household environmental pressure areas. This paper provides an understanding of both direct and indirect (embodied) GHG emissions. Results from the study suggest that the average Latvian exceeds its global fair share of GHG emissions - the average per capita GHG in 2006 was 4.35 t CO2e. The highest household emissions arise from housing (37%), mobility (26%) and food consumption (25%), goods and services together account only for 12% of total household GHG emissions. This study, however, does not cover capital investments in infrastructure (roads, public buildings etc.) which could increase total emission by almost a ton. The study emphasizes that attention must be paid to the lifestyles, infrastructure and institutions that result in considerable amounts of carbon being locked up in the household activities through which people meet their everyday needs. The findings also indicate that policies should be targeted at the segments in society responsible for the highest carbon footprints, ie. housing, food and mobility.

  18. A Touch-screen Experimental Information System Based on JSP%基于JS P技术的触摸屏实验信息系统

    Institute of Scientific and Technical Information of China (English)

    李帅鹏; 林晓珑; 高春歌; 姜永恒

    2013-01-01

    This paper presented a touch-screen experimental information system based on JSP.The construction of this system mainly considers that according to the combination of JSP,JDK and JDBC, we establish an experimental information database,and the client user can use a touch-screen to query, add and delete the contents of the experimental information database by executing standard SQL com-mands on a web page.Compare to the past,the system seems more convenient and quicker.%阐述了一种基于JSP技术的触摸屏实验信息系统。该系统的构建重点考虑了通过JSP、JDK与JDBC技术相结合,建立实验信息数据库,在网页上执行SQL命令,使用触摸屏实现查询、添加和删除服务器上实验信息数据库的内容。

  19. Medición de coeficientes de extinción en CASLEO y características del CCD ROPER-2048B del telescopio JS

    Science.gov (United States)

    Fernández-Lajús, E.; Gamen, R.; Sánchez, M.; Scalia, M. C.; Baume, G. L.

    2016-08-01

    From observations made with the ``Jorge Sahade'' telescope of the Complejo Astronomico El Leoncito, the UBVRI-band extinction coeficients were measured, and some parameters and characteristics of the direct-image CCD camera ROPER 2048B were determined.

  20. Erratum: ``Far-Infrared Photometry of a Statistical Sample of Late-Type Virgo Cluster Galaxies'' (ApJS, 139, 37 [2002])

    Science.gov (United States)

    Tuffs, Richard J.; Popescu, Cristina C.; Pierini, Daniele; Völk, Heinrich J.; Hippelein, Hans; Leech, Kieron; Metcalfe, Leo; Heinrichsen, Ingolf; Xu, Cong

    2002-06-01

    The legends for Figures 9 and 10 were switched. The legend for Figure 9 should read: ``Uncorrected χ2 values derived from fitting the Gaussian models to the maps vs. the corresponding flux densities at 60 μm obtained from integrating the model fit to infinity. The data were plotted as diamonds, except for those galaxies for which the model was an imperfect fit to the data, which were plotted as crosses. The solid line rising for F60>1.5 Jy represents the linear correlations between flux and χ2, as a result of systematic errors due to the oversampling in cross-scan direction. For faint flux densities χ2 is dominated by systematic errors, producing a clumpy distribution at the left-hand side of the plot, with a lower envelope, which we traced by a solid line to guide the eyes.'' The legend for Figure 10 should read: ``Model fits to the observed brightness profiles of all the Virgo galaxies from our sample (except for the interacting system VCC 1673/VCC 1676; see § 6.2.4). Statistical uncertainties for selected map pixels near the extremities and center of the scans are indicated by the 3 σ error bars. The legend is as in Fig. 8.'' In addition, the references to Figures 9 and 10 in the main text should be interchanged. The Press sincerely regrets this error.