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Sample records for jr miller md

  1. John Call Dalton, Jr., MD: America's first neurophysiologist.

    Science.gov (United States)

    Fine, E J; Manteghi, T; Sobel, S H; Lohr, L A

    2000-09-26

    Before the discoveries of John Call Dalton, Jr., MD (1824-1889), innervation of laryngeal muscles, long-term effects of cerebellar lesions, and consequences of raised intracranial pressure were poorly understood. Dalton discovered that the posterior cricoarytenoid muscles adducted the vocal cords during inspiration. He confirmed Flourens' observations that acute ablation of the cerebellum of pigeons caused loss of coordination. Dalton observed that properly cared for pigeons gradually recovered "coordinating power." Dalton observed that prolonged raised intracranial pressure caused tachycardia and then fatal bradycardia in dogs. Before Dalton published his photographic atlas of the human brain, neuroanatomy atlases were sketched by Europeans and imported into the United States. Dalton's atlas of the human brain contained precise photographs of vertical and horizontal sections that equal modern works. Before Dalton introduced live demonstrations of animals, physiology was taught by recitation of texts only. Dalton was the first American-born professor to teach physiology employing demonstrations of live animals operated on under ether anesthesia. He wrote an essay advocating experimentation on animals as the proper method of acquiring knowledge of function and that humane animal experimentation would ultimately improve the health of man and animals. His eloquent advocacy for humane experimental physiology quelled attacks by contemporaneous antivivisectionists. Dalton was America's first experimental neurophysiologist.

  2. The Microcosm within: An interview with William B. Miller, Jr., on the Extended Hologenome theory of evolution.

    Science.gov (United States)

    Hunt, Tam

    2015-01-01

    There is a singular unifying reality underlying every biologic interaction on our planet. In immunology, that which does not kill you makes you different. -William B. Miller, Jr. We are experiencing a revolution in our understanding of inner space on a par with our exponentially increasing understanding of outer space. In biology, we are learning that the genetic and epigenetic complexity within organisms is far deeper than suspected. This is a key theme in William B. Miller Jr.'s book, The Microcosm Within: Evolution and Extinction in the Hologenome. We are learning also that a focus on the human genome alone is misleading when it comes to who we really are as biological entities, and in terms of how we and other creatures have evolved. Rather than being defined by the human genome alone, we are instead defined by the "hologenome," the sum of the human genome and the far larger genetic endowment of the microbiome and symbiotic communities that reside within and around us. Miller is a medical doctor previously in private practice in Pennsylvania and Phoenix, Arizona. This book is his first foray into evolutionary theory. His book could have been titled "The Origin of Variation" because this is his primary focus. He accepts that natural selection plays a role in evolution, but he demotes this mechanism to a less important role than the Modern Synthesis suggests. His main gripe, however, concerns random variation. He argues that random variation is unable to explain the origin and evolution of biological forms that we see in the world around us and in the historical record. Miller suggests that, rather than random variation as the engine of novelty, there is a creative impulse at the heart of cellular life, and even at the level of the genetic aggregate, that generates novelty on a regular basis. I probe this assertion in the interview below. He also highlights the strong role of "exogenous genetic assault" in variation and in his immunological model of evolution.

  3. William Pepper Jr, MD (1843-1898): portrait of a nineteenth-century medical educator.

    Science.gov (United States)

    Lo Re, Vincent; Bellini, Lisa M

    2006-08-01

    Dr William Pepper Jr was a prominent Philadelphia physician whose contributions to medicine in the late 19th century are not widely known. As a young physician he rose in stature rapidly due to his abilities as a diagnostician, teacher, writer and researcher. His primary interest, however, was to improve the education of physicians. He orchestrated the creation of America's first university-controlled teaching hospital, the Hospital of the University of Pennsylvania, enabling substantial improvements in clinical training. Pepper later became Provost of the University of Pennsylvania and ambitiously transformed the curriculum of the medical school, providing greater basic science and clinical training. He also worked to establish several institutes and museums in Philadelphia in order to promote academic pursuits, particularly in medicine. William Pepper Jr was one of the 19th century's foremost medical educators and his accomplishments helped reshape the way medicine was taught throughout the United States.

  4. Human radiation studies: Remembering the early years. Oral history of radiologist Earl R. Miller, M.D., August 9 and 17, 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    Dr. Earl R. Miller was interviewed by representatives of US DOE Office of Human Radiation Research (OHRE). The interview covers Dr. Miller`s involvement with the Manhattan Engineer District, with total body irradiation, and heavy-ion therapy. Dr. Miller`s remembrances include wartime work on radiation exposure, Joe Hamilton, Neutron Therapy research, means of obtaining isotopes, consent forms, infinite laminograms, invention of a baby holder to alleviate exposure of radiological technicians in diagnostic procedures involving infants, and several personages.

  5. From Catheters To Ventricular Assist Devices: 60 Years of Cardiovascular Experiences With William L. Winters, JR., M.D.

    Science.gov (United States)

    Winters, W L

    2015-01-01

    Automatic typewriters, transistor radios, microfiche, black and white television…while considered high-tech in the 1950s, these technologies seem limited when viewed from the 21st century. The same is true for cardiovascular medicine, which back then relied on electrocardiograms and X-rays for most diagnoses. In the 60 years since, advances in medical capabilities have progressed at a staggering pace. Patient research that once required months poring over paper charts is now reduced to hours using electronic medical record databases. Diagnostic images that once took days to process can now be accessed instantly through ultrasound and magnetic resonance imaging. While a half-century ago no one would have imagined accessing any and all information with a 5-second Google search, so too would noninvasive heart surgery been considered unimaginable. Since the 1950s when he graduated from medical school, William L. Winters, Jr., has been a first-hand witness to breathtaking innovations in cardiovascular medicine-both globally and in Houston. Author of Houston Hearts: A History of Cardiovascular Surgery and Medicine at Houston Methodist DeBakey Heart & Vascular Center and long-time medical editor of the Methodist DeBakey Cardiovascular Journal, Dr. Winters sat down with the journal editors this past April to share his insights from the last half-century of medical practice.

  6. Millerism - an historical enigma?

    Directory of Open Access Journals (Sweden)

    Ingemar Lindén

    1975-01-01

    Full Text Available It is a wellknown fact in history that strong bias in the writers and a wishful thinking radically prevent the analysis of any event or religious activity. For this reason Catholic ecclesiastical writers of the old school distorted the role of Martin Luther and his movement; likewise the Radical Reformation fared badly in old handbooks, whether they were composed by Catholics or Lutherans. Again the same principle applies to many of the modern "sects" in America and in Europe. Millerism is an excellent case for illustrating this unfelicitious type of writing. The layman-evangelist William Miller (1782-1849 claimed that the world would never be converted; only the second coming of Christ could usher in the millennium. In order to obtain a better understanding of Millerism, the movement should be divided into three main periods, which differed in character. At first, Miller's own development needs to be ascertained. Though he lacked any thorough intellectual training and remained an autodidact, he nevertheless belonged to the wide range of middle class Yankees. To be sure, Miller lived not too far from the famous frontier in his youth, but despite preconceived ideas in some writers, Miller had his cultural roots in the built-up areas of a New England society. The second important stratum in his personality was the warm Baptist revivalism, which prevailed in his home. Deism and revivalism thus contended for the supremacy of his soul; admitting the later dominance of evangelical revivalism, reason and order continued to hold a place in his mental set-up.

  7. Recurrent Miller Fisher syndrome.

    Science.gov (United States)

    Madhavan, S; Geetha; Bhargavan, P V

    2004-07-01

    Miller Fisher syndrome (MFS) is a variant of Guillan Barre syndrome characterized by the triad of ophthalmoplegia, ataxia and areflexia. Recurrences are exceptional with Miller Fisher syndrome. We are reporting a case with two episodes of MFS within two years. Initially he presented with partial ophthalmoplegia, ataxia. Second episode was characterized by full-blown presentation characterized by ataxia, areflexia and ophthalmoplegia. CSF analysis was typical during both episodes. Nerve conduction velocity study was fairly within normal limits. MRI of brain was within normal limits. He responded to symptomatic measures initially, then to steroids in the second episode. We are reporting the case due to its rarity.

  8. Interview: Sarah Miller

    Directory of Open Access Journals (Sweden)

    Richelle E. Wescott

    2012-01-01

    Full Text Available While still an undergraduate, Sarah Miller served as the Architecture and Design Manager for Purdue’s INHome project, which constructed a self-sufficient solar home for the Department of Energy’s Solar Decathlon. Despite this being Purdue's first time participating in the international contest, the entry earned second place.

  9. Special Article: Ronald D. Miller: tribute to a past editor-in-chief.

    Science.gov (United States)

    Tuman, Kenneth J

    2012-12-01

    For anesthesiologists around the world who have practiced or trained in the past 4 decades, the name Ronald Miller, MD, has been synonymous with a commitment to excellence that has been evident in all aspects of his remarkable career as a distinguished clinician-scientist, editor, writer, and educator. Dr. Miller's contributions as Editor-in-Chief of Anesthesia & Analgesia (1991-2006) have stimulated this salutation of his career and of his influence on transforming the Journal.

  10. Injection MD

    CERN Document Server

    Bartmann, W; Bracco, C; Drosdal, L; Gianfelice, E; Goddard, B; Kain, V; Papaphilippou, Y; Vanbavinckhove, G

    2012-01-01

    This note summarizes the results obtained at injection during the 2nd MD block and the floating MD block in July. Highlights are presented for injection in the LHC with the Q20 SPS optics, influence of the supercycle and injection with 25 ns bunch spacing. Beams were successfully injected into the LHC using the Q20 optics [1, 3]. Small corrections were needed to steer the beam in the transfer lines. Dispersion measurements were conducted for both beams. The horizontal normalized dispersion in TI2 was a factor 2 smaller for Q20 with respect to Q26, for TI8 on the other hand the opposite was observed. The results for injection loss dependency on super cycle composition show only a small increase in losses for beam 2. The losses observed must therefore mainly come from other sources such as shot-by-shot stability or quality of scraping. For the injection with 25 ns bunch spacing bunches were injected for both beams. For B1 up to the maximum of 288 bunches. For B2 on the other only up to 144 bunches were injected...

  11. Conducting Miller-Urey Experiments

    Science.gov (United States)

    Parker, Eric Thomas; Cleaves, Henderson James; Burton, Aaron S.; Glavin, Daniel P.; Dworkin, Jason; Zhou, Manshui; Bada, Jeffrey L.; Fernandez, Facundo M.

    2014-01-01

    In 1953, Stanley Miller reported the production of biomolecules from simple gaseous starting materials, using apparatus constructed to simulate the primordial Earth's atmosphere-ocean system. Miller introduced 200 ml of water, 100 mmHg of H2, 200mmHg of CH4, and 200mmHg of NH3 into the apparatus, then subjected this mixture, under reflux, to an electric discharge for a week, while the water was simultaneously heated. The purpose of this manuscript is to provide the reader with a general experimental protocol that can be used to conduct a Miller-Urey type spark discharge experiment, using a simplified 3 L reaction flask. Since the experiment involves exposing inflammable gases to a high voltage discharge, it is worth highlighting important steps that reduce the risk of explosion. The general procedures described in this work can be extrapolated to design and conduct a wide variety of electric discharge experiments simulating primitive planetary environments.

  12. Conducting Miller-Urey Experiments

    OpenAIRE

    Parker, Eric T.; Cleaves, James H.; Burton, Aaron S.; Glavin, Daniel P.; Dworkin, Jason P.; Zhou, Manshui; Bada, Jeffrey L; Fernández, Facundo M.

    2014-01-01

    In 1953, Stanley Miller reported the production of biomolecules from simple gaseous starting materials, using an apparatus constructed to simulate the primordial Earth's atmosphere-ocean system. Miller introduced 200 ml of water, 100 mmHg of H2, 200 mmHg of CH4, and 200 mmHg of NH3 into the apparatus, then subjected this mixture, under reflux, to an electric discharge for a week, while the water was simultaneously heated. The purpose of this manuscript is to provide the reader with a general ...

  13. Conducting miller-urey experiments

    National Research Council Canada - National Science Library

    Parker, Eric T; Cleaves, James H; Burton, Aaron S; Glavin, Daniel P; Dworkin, Jason P; Zhou, Manshui; Bada, Jeffrey L; Fernández, Facundo M

    2014-01-01

    ... the water was simultaneously heated. The purpose of this manuscript is to provide the reader with a general experimental protocol that can be used to conduct a Miller-Urey type spark discharge experiment, using a simplified 3 L reaction flask...

  14. Implementing the Kustin-Miller complex construction

    CERN Document Server

    Boehm, Janko

    2011-01-01

    The Kustin-Miller complex construction, due to A. Kustin and M. Miller, can be applied to a pair of resolutions of Gorenstein rings with certain properties to obtain a new Gorenstein ring and a resolution of it. It gives a tool to construct and analyze Gorenstein rings of high codimension. We describe the Kustin-Miller complex and its implementation in the Macaulay2 package KustinMiller, and explain how it can be applied to explicit examples.

  15. [Charles Miller Fisher: a giant of neurology].

    Science.gov (United States)

    Tapia, Jorge

    2013-08-01

    C. Miller Fisher MD, one of the great neurologists in the 20th century, died in April 2012. Born in Canada, he studied medicine at the University of Toronto. As a Canadian Navy medical doctor he participated in World War II and was a war prisoner from 1941 to 1944. He did a residency in neurology at the Montreal Neurological Institute between 1946 and 1948, and later on was a Fellow in Neurology and Neuropathology at the Boston City Hospital. In 1954 he entered the Massachusetts General Hospital as a neurologist and neuropathologist, where he remained until his retirement, in 2005. His academic career ended as Professor Emeritus at Harvard University. His area of special interest in neurology was cerebrovascular disease (CVD). In 1954 he created the first Vascular Neurology service in the world and trained many leading neurologists on this field. His scientific contributions are present in more than 250 publications, as journal articles and book chapters. Many of his articles, certainly not restricted to CVD, were seminal in neurology. Several concepts and terms that he coined are currently used in daily clinical practice. The chapters on CVD, in seven consecutive editions of Harrison's Internal Medicine textbook, are among his highlights. His death was deeply felt by the neurological community.

  16. DCEG Symposium to Honor Joseph F. Fraumeni, Jr. | Poster

    Science.gov (United States)

    By Nancy Parrish, Staff Writer On May 6, the Division of Cancer Epidemiology and Genetics (DCEG) will sponsor a symposium to honor 50 years of leadership from its founding director, Joseph F. Fraumeni, Jr., M.D., who stepped down from the position in July 2012. The conference, entitled “Cancer Epidemiology: From Pedigrees to Populations,” will highlight critical findings in cancer epidemiology from the last 50 years, as well as opportunities for future research directions. Long History of Leadership and Discovery

  17. 33 CFR 165.507 - Security Zone; Chesapeake Bay, between Sandy Point and Kent Island, MD.

    Science.gov (United States)

    2010-07-01

    ... south (eastbound) span of the William P. Lane Jr. Memorial Bridge, from the western shore at Sandy Point..., between Sandy Point and Kent Island, MD. 165.507 Section 165.507 Navigation and Navigable Waters COAST... Guard District § 165.507 Security Zone; Chesapeake Bay, between Sandy Point and Kent Island, MD. (a...

  18. Bob miller's math for the GMAT

    CERN Document Server

    Miller, Bob

    2012-01-01

    Maximize Your GMAT Math Score with Bob Miller! REA's updated second edition of Bob Miller's Math for the GMAT is a must for anyone taking the GMAT. Bob Miller has taught math to thousands of students at all educational levels for 30 years. His proven teaching methods will help you master the math section of the GMAT and boost your score! Written in a lively and unique format, Bob Miller's Math for the GMAT prepares GMAT-takers with everything they need to know. Unlike some dull test preps that merely present the material, Bob actually teaches and explains math concepts and ideas. His no-no

  19. Cryptanalysis of MD2

    DEFF Research Database (Denmark)

    Knudsen, Lars Ramkilde; Mathiassen, John Erik; Muller, Frédéric

    2010-01-01

    This paper considers the hash function MD2 which was developed by Ron Rivest in 1989. Despite its age, MD2 has withstood cryptanalytic attacks until recently. This paper contains the state-of-the-art cryptanalytic results on MD2, in particular collision and preimage attacks on the full hash...

  20. The Words of Martin Luther King, Jr.

    Science.gov (United States)

    Today's Education, 1979

    1979-01-01

    Excerpts from speeches by Dr. Martin Luther King, Jr., are reprinted. Topics discussed include discrimination, the South, education, nonviolent resistance, poverty, economic opportunity, and world peace. (LH)

  1. A critical evaluation of the Miller and Miller similar media theory for application to natural soils

    Science.gov (United States)

    Sadeghi, Morteza; Ghahraman, Bijan; Warrick, Arthur W.; Tuller, Markus; Jones, Scott B.

    2016-05-01

    The Miller-Miller similar media theory is widely applied to characterize the spatial variability of soil hydraulic properties. For a group of soils, a distinct scaling factor is commonly assigned to each individual soil to coalesce the soil water characteristic and hydraulic conductivity functions to single curves. It is generally assumed that the Miller-Miller theory is valid as long as soils are "similar" either with regard to their microscopic pore space geometry or the closely related macroscopic soil hydraulic functions. In this paper, it is illustrated that similarity is not the sole required condition for validity of the Miller-Miller theory. In addition, the interrelation between the soil water characteristic and the hydraulic conductivity functions considered for scaling need to be comparable. The interrelation is dependent not only on the pore space geometry, but also on solid-liquid interactions. Hence similar interrelation cannot be concluded from similarity of microscopic pore space geometry. A dimensionless parameter termed the "joint scaling factor" was defined and applied to evaluate the soundness of the interrelation condition for 26 soils from the UNSODA database that were grouped into six classes of similar soils. Obtained results clearly reveal the crucial importance of the interrelation condition for the Miller-Miller scaling theory, which has been hidden behind the "similarity" requirement, and contradict the general belief that Miller-Miller scaling is valid as long as soils are "similar."

  2. Evidence from Ethiopian Grain Traders and Millers

    African Journals Online (AJOL)

    Daniel

    poverty alleviation strategy, medium firms such as most grain traders and millers .... However, financial repression such as high inflation, high reserve requirement of ... deposit and lending interest rates can hinder the development of financial.

  3. MD SIMULATION FOR NANOCRYSTALS

    Institute of Scientific and Technical Information of China (English)

    马新玲; 杨卫

    2003-01-01

    Molecular dynamic (MD) provided an ab initio simulation for nano-scale mechanical behavior of materials, provided that the inter-atomic potential is accurately prescribed. MD is particularly suitable in simulating the formation, the deformation, and the evolution of nanocrystals under a fast strain rate. To tackle large scale system and nano-seconds time duration, parallel algorithm is desired. The present paper reviews the recent advances in MD simulation for nanocrystals with attention focused on the applications toward nanomechanics. The examined issues are: formation of nanocrystalline metals, nanoindentation on nanocrystals, fast deformation of nanocrystals, orderdisorder transition, and nano-particle impact.

  4. Muscular Dystrophy (MD)

    Science.gov (United States)

    ... fight respiratory infections. Some individuals may benefit from occupational therapy and assistive technology. Some ... (MD) are a group of more than 30 genetic diseases characterized by progressive weakness and degeneration of the ...

  5. Edward Wheeler Hones Jr. (1922-2012)

    Science.gov (United States)

    Baker, Daniel N.; McPherron, Robert L.; Birn, Joachim

    2013-02-01

    Space physicist Edward Wheeler Hones Jr. died on 17 September 2012 at his home in Los Alamos, N. M. He was 90 years old. The cause of death was a heart attack that came following a brief hospitalization.

  6. George A. Miller (1920-2012).

    Science.gov (United States)

    Pinker, Steven

    2013-09-01

    Presents an obituary for George A. Miller (1920-2012). Miller ranks among the most important psychologists of the 20th century. In addition to writing one of the best known papers in the history of psychology ("The Magical Number Seven, Plus or Minus Two: Some Limits on Our Capacity for Processing Information," published in Psychological Review in 1956), Miller also fomented the cognitive revolution, invented psycholinguistics and cognitive psychology, imported powerful ideas from the theories of information, communication, grammar, semantics, and artificial intelligence, and left us a sparkling oeuvre that proves that a rigorous scientist needn't write in soggy prose. Honors rained down on Miller. APA gave him the Award for Distinguished Scientific Contributions (1963), the American Psychological Foundation Gold Medal Award for Life Achievement in Psychological Science (1990), the William James Book Award (1992, for The Science of Words), and the Award for Lifetime Contributions to Psychology (2003), and named a prize after him, as did the Cognitive Neuroscience Society. Miller was also honored by the Association for Psychological Science and the American Speech and Hearing Association. In 2000, he won the John P. McGovern Award in the Behavioral Sciences from the American Association for the Advancement of Science, and in 1991, the National Medal of Science, the country's highest scientific honor.

  7. MD-2 binds cholesterol.

    Science.gov (United States)

    Choi, Soo-Ho; Kim, Jungsu; Gonen, Ayelet; Viriyakosol, Suganya; Miller, Yury I

    2016-02-19

    Cholesterol is a structural component of cellular membranes, which is transported from liver to peripheral cells in the form of cholesterol esters (CE), residing in the hydrophobic core of low-density lipoprotein. Oxidized CE (OxCE) is often found in plasma and in atherosclerotic lesions of subjects with cardiovascular disease. Our earlier studies have demonstrated that OxCE activates inflammatory responses in macrophages via toll-like receptor-4 (TLR4). Here we demonstrate that cholesterol binds to myeloid differentiation-2 (MD-2), a TLR4 ancillary molecule, which is a binding receptor for bacterial lipopolysaccharide (LPS) and is indispensable for LPS-induced TLR4 dimerization and signaling. Cholesterol binding to MD-2 was competed by LPS and by OxCE-modified BSA. Furthermore, soluble MD-2 in human plasma and MD-2 in mouse atherosclerotic lesions carried cholesterol, the finding supporting the biological significance of MD-2 cholesterol binding. These results help understand the molecular basis of TLR4 activation by OxCE and mechanisms of chronic inflammation in atherosclerosis.

  8. Fighting desires: Henry Miller's Queer Tropic.

    Science.gov (United States)

    Hardin, Michael

    2002-01-01

    "Fighting Desires: Henry Miller's Queer Tropic" is an investigation of Tropic of Cancer that investigates the deeply repressed homoerotic desire that periodically surfaces. This reading is dependent upon an interpretation of Eve Sedgwick that proposes male sexuality as a continuum. By looking at the nature of the male-male relationships, as well as the lack of emotion and presence in the male-female relationships, I will show that the most intimate relationships are between men, and that these relationships are expressed through the telling of stories about (heterosexual) sex; this is the function of women within the novel: one has sex with a woman, not for the pleasure that the act brings, but for the pleasure that the recounting of the story to other men brings. Furthermore, I will look at Miller's use of puns within the novel and how they also contribute to a homoerotic reading. None of this is to argue that Miller was not homophobic and sexist--Miller very clearly was--the purpose of this essay is to show the complex nature of sexuality, even within a protagonist who asserts a very defined heterosexuality.

  9. Genes and schizophrenia: from a Festschrift Seminar honoring William T. Carpenter Jr, MD.

    Science.gov (United States)

    Malhotra, Anil K

    2014-03-01

    Recent data have begun to elucidate the genetic architecture of schizophrenia, as well as provide new insights into the relationships of specific genetic factors across diagnostic boundaries, with specific symptom domains, and in the prediction of antipsychotic treatment response. Not surprisingly, work conducted at the Maryland Psychiatric Research Center (MPRC), led by Dr William Carpenter, has helped to guide the thinking behind much of this work, as well as contributed valuable data toward these efforts. In this article, I will briefly summarize some of the major findings emerging from these lines of research and highlight the role of the Dr Carpenter and his colleagues at the MPRC in this area.

  10. 77 FR 57116 - Cleveland J. Enmon, Jr., M.D.; Decision and Order

    Science.gov (United States)

    2012-09-17

    ... lower back pain stemming from a car accident in which she was ejected from the vehicle. . Despite this... medications and lifestyle changes, diet, exercise, heat applications, physical therapy, possibly...

  11. Living history: G. Edgar Folk, Jr.

    Science.gov (United States)

    Tipton, Charles M

    2008-06-01

    In 2005, the American Physiological Society (APS) initiated the Living History Project to recognize senior members who have made significant contributions during their career to the advancement of the discipline and profession of physiology. During 2007, the APS Section of Environmental and Exercise Physiology selected Prof. G. Edgar Folk, Jr., of the University of Iowa to be profiled in Advances in Physiology Education.

  12. Martin Luther King, Jr. Resource Guide.

    Science.gov (United States)

    New York State Education Dept., Albany. Div. of Civil Rights and Intercultural Relations.

    This resource guide was developed to commemorate Dr. Martin Luther King, Jr.'s birthday by providing school personnel with background information and hands-on activities for use with students in Grades K-12. The activities in the guide can be implemented throughout the school year to help students become aware of the social, economic, and…

  13. Martin Luther King, Jr. Teacher's Resource Manual.

    Science.gov (United States)

    Connecticut State Dept. of Education, Hartford.

    This Connecticut teachers' manual on Martin Luther King, Jr. includes: (1) teacher background information; (2) five excerpts from King's speeches; (3) four themes for lesson plans; and (4) sample lesson plans. The teacher's background information provides biographical sketches of King and his precursors. The five speeches reproduced here are…

  14. Views of Dr. Martin Luther King, Jr.

    Science.gov (United States)

    Davis, Alan H.

    1990-01-01

    Discusses views of Martin Luther King, Jr., including concepts of human rights, related counseling approaches, and ethics. Claims King's views provide helpful insights for counselors and clients. Concludes King invited individuals to view challenging life situations as moral opportunities. (Author/ABL)

  15. Books about Martin Luther King, Jr.

    Science.gov (United States)

    Woll, Christina B.

    1990-01-01

    Briefly reviews three recent biographies of Martin Luther King, Jr. that also deal with the civil rights movement. Summarizes contents and identifies reading ability levels appropriate for elementary and junior high students. Recommends six additional King biographies for children. Also endorses two filmstrips on King and the movement. Gives full…

  16. Prebiotic Soup: Revisiting the Miller Experiment

    Science.gov (United States)

    Bada, Jeffrey L.; Lazcano, Antonio

    2003-01-01

    Isn't life wonderful? sang Alma Cogan and Les Howard in their almost forgotten 1953 hit. That same year, Stanley L. Miller raised the hopes of understanding the origin of life when on 15 May, Science published his paper on the synthesis of amino acids under conditions that simulated primitive Earth's atmosphere. Miller had applied an electric discharge to a mixture of CH4, NH3, H2O, and H2 - believed at the time to be the atmospheric composition of early Earth. Surprisingly, the products were not a random mixture of organic molecules. but rather a relatively small number of biochemically significant compounds such as amino acids, hydroxy acids, and urea. With the publication of these dramatic results, the modern era in the study of the origin of life began.

  17. Prebiotic Soup-Revisiting the Miller Experiment

    Science.gov (United States)

    Bada, Jeffrey L.; Lazcano, Antonio

    2003-01-01

    'Isn't life wonderful?' sang Alma Cogan and Les Howard in their almost forgotten 1953 hit. That same year, Stanley L. Miller raised the hopes of understanding the origin of life when on 15 May, Science published his paper on the synthesis of amino acids under conditions that simulated primitive Earth's atmosphere. Miller had applied an electric discharge to a mixture of CH4, NH3, H2O, and H2 - believed at the time to be the atmospheric composition of early Earth. Surprisingly, the products were not a random mixture of organic molecules, but rather a relatively small number of biochemically significant compounds such as amino acids, hydroxy acids, and urea. With the publication of these dramatic results, the modem era in the study of the origin of life began.

  18. Recurrent Miller fisher syndrome : a case report.

    Directory of Open Access Journals (Sweden)

    Sitajayalakshmi S

    2002-07-01

    Full Text Available Miller fisher syndrome (MFS is a variant of Guillain-Barre syndrome characterized by the triad of ophthalmoplegia, ataxia and areflexia. Recurrences are exceptional with MFS. A case with two episodes of MFS within four years is reported. He presented with findings of ophthalmoplegia, ataxia, areflexia, and oropharyngeal weakness and mild distal sensory impairment during both episodes. Electrophysiological findings showed reduced compound muscle action potentials and sensory nerve action potentials with no evidence of conduction blocks. Nerve biopsy showed segmental demyelination. MRI of brain was normal. He responded well to immunoglobulins during both episodes suggesting that immunomodulating drugs have a role in the treatment of MFS.

  19. Arnold Aberman, MD.

    Science.gov (United States)

    Aberman, A

    1995-10-01

    When the United States embarked on its effort to provide universal health insurance, the Canadian Medicare System was cited as a possible model for American health care. Often touted as an example of low-cost, high quality medicine, the Canadian system has mirrored the problems of health care across its southern border. With rocketing health care expenditures and financing having largely been decentralized to the individual provinces, local officials have struggled to cut costs and services. A central focus of these efforts has been a move to decrease the numbers of physicians, most notably a 10% decrease in medical school class size in 1993. While some Western provinces have experimented with the privatization of health care, the Canadian system still remains the epitome of government operated fee-for-service medicine. Given the likelihood of dramatic change in the American Medicare system, Canadian academic centers offer a unique perspective on the impact of capitation, evolving relationships with government payors, and the flip side of market oriented reforms. At the helm of one of Canada's largest schools is Arnold Aberman, MD, dean of the University of Toronto Faculty of Medicine. Born in Montreal, Quebec, Aberman received his MD from McGill University, but then did his residency both in Canada and the US, followed by a pulmonary fellowship at Albert Einstein College of Medicine and the Cardiovascular Research Institute of the University of California, San Francisco. Interviewed at his office in Toronto, Aberman reflected on the trials and tribulations confronting medicine on both sides of the 48th parallel.

  20. Entrevista con Jacques-Alain Miller.

    Directory of Open Access Journals (Sweden)

    Francisco Estévez González

    1987-01-01

    Full Text Available Jacques-Alain MILLER es psicoanalista, editor -uno de cuyos principales cometidos consiste en establecer los textos y la publicación de los Seminarios de Jacques LACAN, tal como le encargó el propio maestro escritor, prestigioso conferenciante y profesor especializado en los fundamentos del psicoanálisis. En la actualidad dirige el Departamento de Psicoanálisis de la Universidad de París VIII. Es miembro del Consejo de la Escuela de la Causa Freudiana, editor de las publicaciones del Campo Freudiano y director de la revista Ornicar, una de las más importantes publicaciones psicoanalíticas en el panorama internacional. Está casado con Judith MILLER -hija de LACAN-, presidenta de la Fundación del Campo Freudiano, con la que tiene dos hijos. Ha visitado España en numerosas ocasiones, pronunciando conferencias, dictando seminarios e impulsando la articulación de grupos de estudio psicoanalíticos en diversas ciudades. Es asesor editorial de la revista «El Analiticón», publicación del Campo Freudiano en España.

  1. ADT fast losses MD

    CERN Document Server

    Priebe, A; Dehning, B; Redaelli, S; Salvachua Ferrando, BM; Sapinski, M; Solfaroli Camillocci, M; Valuch, D

    2013-01-01

    The fast beam losses in the order of 1 ms are expected to be a potential major luminosity limitation for higher beam energies after the LHC long shutdown (LS1). Therefore a Quench Test is planned in the winter 2013 to estimate the quench limit in this timescale and revise the current models. This experiment was devoted to determination the LHC Transverse Damper (ADT) as a system for fast losses induction. A non-standard operation of the ADT was used to develop the beam oscillation instead of suppressing them. The sign flip method had allowed us to create the fast losses within several LHC turns at 450 GeV during the previous test (26th March 2012). Thus, the ADT could be potentially used for the studies of the UFO ("Unidentied Falling Object") impact on the cold magnets. Verification of the system capability and investigations of the disturbed beam properties were the main objectives of this MD. During the experiment, the pilot bunches of proton beam were excited independently in the horizontal and vertical ...

  2. Miller-Urey Synthesis in the Nuclei of Galaxies

    Science.gov (United States)

    Wickramasinghe, N. C.; Hoyle, F.

    The most promising venues for the synthesis of prebiotic molecules by Miller-Urey type processes may be found near the centres of galaxies. Explosions of supermassive stars would produce the basic chemical elements necessary to make molecules in high-density mass flows that are then acted upon by ionizing radiation, thus simulating the conditions needed for Miller-Urey type processing.

  3. Unilateral external ophthalmoplegia in Miller Fisher syndrome: case report

    Directory of Open Access Journals (Sweden)

    Severn Philip

    2007-04-01

    Full Text Available Abstract Background A description of the diagnostic features of Miller Fisher syndrome. Case presentation The clinical presentation, investigation, and subsequent progress of our patient with clinical unilateral external ophthalmoplegia. Conclusion Our case demonstrates the presentation of clinical unilateral external ophthalmoplegia as part of the full triad of Miller Fisher syndrome.

  4. MD5算法研究%MD5 Algorithm

    Institute of Scientific and Technical Information of China (English)

    张裔智; 赵毅; 汤小斌

    2008-01-01

    随着网络技术的迅速发展,信息加密技术已成为保障网络安全的一种重要手段,加密算法已经成为人们的一个研究热点.本文对MD5算法进行了深入研究,介绍MD5算法的产生背景、应用及其算法流程,并提出了MD5算法的一个改进方案.

  5. Antibacterial activity of Coriandrum sativum L. and Foeniculum vulgare Miller Var. vulgare (Miller) essential oils.

    Science.gov (United States)

    Lo Cantore, Pietro; Iacobellis, Nicola S; De Marco, Adriana; Capasso, Francesco; Senatore, Felice

    2004-12-29

    Essential oils were extracted from the fruits of Coriandrum sativum L. and Foeniculum vulgare Miller var. vulgare (Miller) and assayed in vitro for antibacterial activity to Escherichia coli and Bacillus megaterium, bacteria routinely used for comparison in the antimicrobial assays, and 27 phytopathogenic bacterial species and two mycopathogenic ones responsible for cultivated mushroom diseases. A significant antibacterial activity, as determined with the agar diffusion method, was shown by C. sativum essential oil whereas a much reduced effect was observed for F. vulgare var. vulgare oil. C. sativum and F. vulgare var. vulgare essential oils may be useful natural bactericides for the control of bacterial diseases of plants and for seed treatment, in particular, in organic agriculture. The significant antibacterial activity of essential oils to the bacterial pathogens of mushrooms appears promising.

  6. Tribute to A. W. Castleman, Jr.

    Energy Technology Data Exchange (ETDEWEB)

    Knappenberger, Jr., Kenneth L.; Johnson, Grant E.; El-Sayed, Mostafa A.

    2014-09-18

    It is with great pleasure that we join our many colleagues who contributed to this special issue of The Journal of Physical Chemistry A in dedicating it in honor of Professor A. W. “Will” Castleman, Jr. Will is a pioneer in the field of cluster science, and the far-reaching impact of his career is demonstrated by the broad range of topics covered in this issue. This diversity validates Will’s teaching that “fundamental research in cluster science allows you to explore any problem you want”. This ability to extend to other research areas comes because, as Will has shown both rigorously and elegantly, clusters are an intermediate state of matter that bridge the gap between molecular and bulk levels.

  7. Ultra light weight jet engine JR100; Chokeiryo jet engine JR100

    Energy Technology Data Exchange (ETDEWEB)

    Matsuki, M. [Nippon Institute of Technology, Saitama (Japan)

    1999-03-20

    As a part of the jet lift V/STOL research by National Aerospace Laboratory, a study of trial manufacture of ultra light weight jet engine JR 100 started in FY 1964. The study was aimed at obtaining a lift engine for VTOL and founding the base for the future jet lift VTOL, and at taking in the results of the jet engine element study accumulated so far and manufacturing an advanced engine. Decided on the use of domestic materials for JR 100, the materials to be used are almost iron-based ones. Through the efforts for weight reduction in structure and processing, a thrust/weight ratio of 10 was realized. At the same time, the production/processing of light weight materials such as titanium alloys was proceeded with, and by adopting the materials to JR 200 system, a thrust/weight ratio of 15 was realized. Together with these, for the purpose of reducing the fuel consumption rate, studies started on fan for lift fan engine and high temperature turbine (an inlet temperature of 1250 degrees C was achieved), to get low noise/high efficiency fan. By the research results, the basis for jet lift VTOL was established, and it became the basis for the development of turbo fan engine FJR 710. (NEDO)

  8. The Newest Monument: The Martin Luther King, Jr. National Memorial

    Science.gov (United States)

    Social Studies and the Young Learner, 2011

    2011-01-01

    This article features the newest monument, the Martin Luther King, Jr. National Memorial. The memorial on the National Mall in Washington, D.C., honoring Dr. Martin Luther King, Jr. will be an engaging landscape experience to convey four fundamental and recurring themes throughout Dr. King's life--democracy, justice, hope, and love. Natural…

  9. Voldemar Miller ja kodu-uurimisliikumine / Eva Maaring

    Index Scriptorium Estoniae

    Maaring, Eva

    2011-01-01

    Eesti NSV Teaduste Akadeemia kodu-uurimise komisjoni liikmeks kinnitati Voldemar Miller 1961. aastal. Ta oli Tallinna Linnamuuseumi kodu-uurimisringi asutaja (1963) ja juht. Voldemar Millerist kui kodu-uurimistöö juhendajast, õpetajast ja mõtestajast

  10. NOAA Ship Miller Freeman Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Miller Freeman Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  11. Draft genome sequence of Therminicola potens strain JR

    Energy Technology Data Exchange (ETDEWEB)

    Byrne-Bailey, K.G.; Wrighton, K.C.; Melnyk, R.A.; Agbo, P.; Hazen, T.C.; Coates, J.D.

    2010-07-01

    'Thermincola potens' strain JR is one of the first Gram-positive dissimilatory metal-reducing bacteria (DMRB) for which there is a complete genome sequence. Consistent with the physiology of this organism, preliminary annotation revealed an abundance of multiheme c-type cytochromes that are putatively associated with the periplasm and cell surface in a Gram-positive bacterium. Here we report the complete genome sequence of strain JR.

  12. Walter Rowe Courtenay, Jr. (1933–2014)

    Science.gov (United States)

    Benson, Amy J.

    2016-01-01

    WALTER R. COURTENAY, JR., ichthyologist and retired professor, Florida Atlantic University, Boca Raton, Florida, died in Gainesville, Florida, on 30 January 2014 at age 80. Walt was born in Neenah, Wisconsin, on 6 November 1933, son of Walter and Emily Courtenay. Walt's interest in fish began at a young age as evidenced by a childhood diary in which at 13 years of age he wrote about his first catch—a two-and-a-half pound “pike” from Lake Winnebago. When Walt turned ten, the family moved from Wisconsin to Nashville, Tennessee, the move precipitated by his father accepting a position as pastor of the First Presbyterian Church. During those early days in Nashville, Walt's father would take summers off and travel to Michigan to teach at Camp Miniwanca along the shore of Lake Michigan where father and son honed their angling skills. It was also at that time Walt's father had definite views on what his son should be doing in adult life—in Walt's case it was to become a medical doctor. However, his Woods Hole internship in marine biology and oceanography toward the end of his undergraduate years was a transformative experience for him so much so that he abandoned all ideas of becoming a medical doctor and instead specialized in ichthyology and oceanography. Apart from the inherent interest and opportunities Woods Hole opened to him, being back at the shore of a large body of water, in this case the Atlantic Ocean, was far more interesting than sitting in lectures on organic chemistry. With that, Walt completed his B.A. degree at Vanderbilt University in 1956. In 1960 while in graduate school in Miami, Walt met and married Francine Saporito, and over the next several years had two children, Walter III and Catherine. He went on to receive his M.S. in 1961 from The Rosenstiel School of Marine and Atmospheric Science at the University of Miami on the systematics of the genus Haemulon (grunts) and his Ph.D. degree in 1965 working under his advisor C. Richard

  13. Pairing Relationships Among Feldspathic Lunar Meteorites from Miller Range, Antarctica

    Science.gov (United States)

    Zeigler, Ryan A.; Korotev, R. L.; Jolliff, B. L.

    2012-01-01

    The Miller Range ice fields have been amongst the most prolific for lunar meteorites that ANSMET has searched [1-3]. Six different stones have been recovered during the 2005, 2007, and 2009 field seasons: MIL 05035 (142 g), MIL 07006 (1.4 g), MIL 090034 (196 g), MIL 090036 (245 g), MIL 090070 (137 g), and MIL 090075 (144 g). Of these, the five stones collected during the 2007 and 2009 seasons are feldspathic breccias. Previous work on the Miller Range feldspathic lunar meteorites (FLMs) has suggested that they are not all paired with each other [4-5]. Here we examine the pairing relationships among the Miller Range FLMs using petrography in concert with traceand major-element compositions.

  14. MD 751: Train Instability Threshold

    CERN Document Server

    Carver, Lee Robert; Metral, Elias; Salvant, Benoit; Levens, Tom; Nisbet, David; Zobov, M; CERN. Geneva. ATS Department

    2016-01-01

    The purpose of this MD is to measure the octupole current thresholds for stability for a single bunch, and then make an immediate comparison (with the same operational settings) for a train of 72 bunches separated by 25ns. From theory, the expected thresholds should be similar. Any discrepancy between the two cases will be of great interest as it could indicate the presence of additional mechanisms that contribute to the instability threshold, for example electron cloud.

  15. The numerical thermodynamic analysis of Otto-Miller Cycle (OMC

    Directory of Open Access Journals (Sweden)

    Cakir Mehmet

    2016-01-01

    Full Text Available This paper presents a thermodynamic analysis for an irreversible Otto-Miller Cycle (OMC by taking into consideration heat transfer effects and internal irreversibilities resulting from compression and expansion processes. In the analyses, the influences of the miller cycle ratio, combustion and heat loss constants and inlet temperature have been investigated relations with efficiency in dimensionless form. The dimensionless power output and power density and thermal efficiency relations have been computationally obtained versus the engine design parameters with respect to combustion and heat transfer constants. The results demonstrate that the heat transfer and combustion constants have considerable effects on the cycle thermodynamic performance. This situation theoretically verified for OMC.

  16. New Insights into Prebiotic Chemistry from Old Archived Miller Extracts

    Science.gov (United States)

    Parker, Eric T.; Cleaves, H. James; Dworkin, Jason P.; Glavin, Daniel P.; Callahan, Michael P.; Aubrey, Andrew D.; Lazcano, Antonio; Bada, Jeffrey L.

    2011-01-01

    Following the discovery of an archived set of samples from Stanley Miller's early experiments, analyses were undertaken to better understand the diversity of compounds produced from electric discharges acting on reducing gas mixtures. The paper chromatography methods that Miller used in the 1950s were only capable of detecting a few amino acids and were unable to provide substantial quantitative data relative to today's techniques. Current analytical techniques are much more sensitive and selective, and are capable of precisely quantifying a much larger range of amino acids and their enantiomeric abundances. In one study, preserved dried samples produced by Miller using a lesser-known volcanic apparatus which differed from Miller's classic apparatus in that it utilized an aspirator that injected steam into the electric discharge chamber, simulating a volcanic eruption. The volcanic apparatus produced a wider variety of amino acids than the classic configuration. Prebiotic compounds synthesized in these environments may have locally accumulated where they could have undergone further processing. An additional preserved set of samples from an experiment conducted in 1958 were also found in Miller's archived collection. These samples which had been generated using a mixture of CH4, NH3, H2S and CO2 were collected, catalogued, and stored by Miller, but for unknown reasons were never studied. In our analyses a total of 23 amino acids and 4 amines, including 7 organosulfur compounds, were detected in these samples. The major amino acids with chiral centers are racemic within the accuracy of the measurements, indicating that they are not contaminants introduced during sample storage. This experiment marks the first synthesis of sulfur amino acids from spark discharge experiments designed to imitate primordial environments. The relative yield of some amino acids, in particular the isomers of amino butyric acid, are the highest ever found in a spark discharge experiment

  17. 76 FR 53346 - Airworthiness Directives; The Boeing Company Model DC-9-81 (MD-81), DC-9-82 (MD-82), DC-9-83 (MD...

    Science.gov (United States)

    2011-08-26

    ... Model DC-9-81 (MD- 81), DC-9-82 (MD-82), DC-9-83 (MD-83), DC-9-87 (MD-87), and MD-88 Airplanes AGENCY... Jersey Avenue, SE., Washington, DC 20590. Hand Delivery: Deliver to Mail address above between 9 a.m. and...) This AD applies to The Boeing Company Model DC-9-81 (MD-81), DC-9-82 (MD-82), DC-9-83 (MD-83),...

  18. 76 FR 41651 - Airworthiness Directives; The Boeing Company Model DC-9-81 (MD-81), DC-9-82 (MD-82), DC-9-83 (MD...

    Science.gov (United States)

    2011-07-15

    ... Model DC-9-81 (MD- 81), DC-9-82 (MD-82), DC-9-83 (MD-83), DC-9-87 (MD-87), and MD-88 Airplanes AGENCY... Ground Floor, Room W12-140, 1200 New Jersey Avenue, SE., Washington, DC 20590. FOR FURTHER INFORMATION...) This AD applies to The Boeing Company Model DC-9-81 (MD-81), DC-9-82 (MD-82), DC-9-83 (MD-83),...

  19. Modigliani-Miller, Basel 3 and CRD 4

    DEFF Research Database (Denmark)

    Balling, Morten

    2015-01-01

    Since 2007, bank capital regulation has been strengthened in Europe and globally. Bank organizations have expressed serious concerns about the impact of higher capital requirements on bank funding costs adn on the lending capacity of banks. The message of a 1958-Article by Modigliani and Miller...

  20. Continued misinterpretation of confidence intervals : Response to Miller and Ulrich

    NARCIS (Netherlands)

    Morey, Richard D.; Hoekstra, Rink; Rouder, Jeffrey N.; Wagenmakers, Eric-Jan

    2015-01-01

    Miller and Ulrich (2015) critique our claim (Hoekstra et al., Psychonomic Bulletin & Review, 21(5), 1157–1164, 2014), based on a survey given to researchers and students, of widespread misunderstanding of confidence intervals (CIs). They suggest that survey respondents may have interpreted the state

  1. Airway risk factors for the Miller laryngoscope blade.

    Science.gov (United States)

    Landry, William B; Nossaman, Bobby D

    2016-09-01

    The purpose of this study was to analyze previously reported airway risk factors in the performance of Miller laryngoscopy and orotracheal intubation. Prospective, observational study. Operating rooms. A total of 978 American Society of Anesthesiologists I-III adults requiring general orotracheal anesthesia for elective surgery. None. Nine previously reported airway risk factors used in predicting difficult laryngoscopy, modified McCormack-Lehane views observed during initial unaided Miller blade laryngoscopy, and number of attempts or need for alternate airway tools to facilitate orotracheal intubation. Orotracheal intubation occurred in 941 of 978 (96.2%) patients with the Miller blade, although 8 patients required 3 attempts, with the remaining 37 patients requiring alternate airway tools. There were no failed orotracheal intubations. Multivariable analysis revealed that modified Mallampati class, thyromental distance, and ability to prognath were associated with progressively inferior modified Cormack-Lehane views, whereas modified Mallampati class, height, and head and neck extension were associated with progressive difficulty with orotracheal intubation. The Miller blade is highly successful in the performance of direct laryngoscopy for orotracheal intubation. These findings suggest that different sets of airway risk factors affect the process of laryngoscopy and orotracheal intubation. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. Obituary: Leverett Davis, Jr., 1914-2003

    Science.gov (United States)

    Jokipii, Jack Randolph

    2004-12-01

    Professor Leverett Davis Jr., Professor of theoretical physics at the California Institute of Technology, died on June 15, 2003 after a long illness. He was 89 years old. He contributed many important ideas and concepts to theoretical astrophysics and was a pioneer in the in situ scientific exploration of space using observations from spacecraft. Davis was born in Elgin, Illinois on March 3, 1914, the eldest of four children of Louis Leverett Davis and Susan Gulick Davis. His parents moved several times as he grew up because his father, a mining engineer, became involved in different mining operations in the American West. Leverett married Victoria Stocker in June 1943. They had two children who died in childhood and subsequently adopted a son, Jeffrey. His wife and son survive him. Davis's early education was rather fractured and uneven because of the many family moves, with periods of home schooling alternating with regular school. His high school education was, on the other hand, reasonably normal. It was while in high school that he decided that he wanted to do physics or mathematics. He went on to earn his Bachelor of Science degree at Oregon State College in 1936, after which he started graduate studies at the California Institute of Technology, to pursue a graduate degree in physics. His advisor was William V. Houston and Davis received his PhD in 1941 for a thesis on electrical properties in nerves. He briefly entertained the idea of changing to work in biophysics. During World War II, Davis became an integral member of the Caltech project for rockets, which developed a number of different types of rockets used in the war. As a result of this war work, Davis wrote a book on Exterior Ballistics, published by Van Nostrand in 1958. He joined the faculty at the California Institute of Technology in 1946, after several years on campus as an instructor. In all, he taught there for nearly four decades before retiring as Professor of Theoretical Physics in 1981

  3. 28 CFR 79.52 - Criteria for eligibility for claims by uranium millers.

    Science.gov (United States)

    2010-07-01

    ... uranium millers. 79.52 Section 79.52 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CLAIMS UNDER THE RADIATION EXPOSURE COMPENSATION ACT Eligibility Criteria for Claims by Uranium Millers § 79.52 Criteria for eligibility for claims by uranium millers. To establish eligibility for compensation...

  4. Wentworth Miller : "Minu edu saladus? Kunstniku hing ja bürokraadi pulss" / Wentworth Miller ; koost. Triin Tael

    Index Scriptorium Estoniae

    Miller, Wentworth

    2006-01-01

    Cannes'is hotellis Carlton toimunud pressikonverentsist, kus ajakirjanike küsimustele vastasid põnevusseriaali "Põgenemine" peaosatäitjad Wentworth Miller ja Dominic Purcell. Lisaks "Wentworth SL Õhtulehele : "Minu südame võitmiseks tuleb oodata" ja tutvustus "Wentworthi läbimurdefilm täna õhtul ETVs"

  5. Wentworth Miller : "Minu edu saladus? Kunstniku hing ja bürokraadi pulss" / Wentworth Miller ; koost. Triin Tael

    Index Scriptorium Estoniae

    Miller, Wentworth

    2006-01-01

    Cannes'is hotellis Carlton toimunud pressikonverentsist, kus ajakirjanike küsimustele vastasid põnevusseriaali "Põgenemine" peaosatäitjad Wentworth Miller ja Dominic Purcell. Lisaks "Wentworth SL Õhtulehele : "Minu südame võitmiseks tuleb oodata" ja tutvustus "Wentworthi läbimurdefilm täna õhtul ETVs"

  6. Puesta en marcha del sensor fuerza-par JR3

    OpenAIRE

    Hoz Najarro, Carlos de la

    2011-01-01

    Este estudio se engloba dentro de los proyectos realizados por el grupo de trabajo Robotic Lab de la Universidad Carlos III de Madrid para el desarrollo del nuevo Humanoide RH-2. Concretamente, implementaremos sobre software libre (Linux) una aplicación C++ que nos permita obtener de la tarjeta de adquisición de datos de 4 puertos PCI P/N 1593 de JR3 inc., en tiempo real, los valores de fuerza/par del sensor industrial Force Moment Sensor 85M35A3-I40-DH12, de la compañía JR3 inc., que llevará...

  7. Mesothelioma in Quebec chrysotile miners and millers: epidemiology and aetiology.

    Science.gov (United States)

    McDonald, A D; Case, B W; Churg, A; Dufresne, A; Gibbs, G W; Sébastien, P; McDonald, J C

    1997-12-01

    In a cohort of some 11,000 men born 1891-1920 and employed in the Quebec chrysotile production industry, including a small asbestos products factory, of 9780 men who survived into 1936, 8009 are known to have died before 1993, 38 probably from mesothelioma--33 in miners and millers and five in factory workers. Among the 5041 miners and millers at Thetford Mines, there had been 4125 deaths from all causes, including 25 (0.61%) from mesothelioma, a rate of 33.7 per 100,000 subject-years; the corresponding figures for the 4031 men at Asbestos were eight out of 3331 (0.24%, or 13.2 per 100,000 subject-years). At the factory in Asbestos, where all 708 employees were potentially exposed to crocidolite and/or amosite, there were 553 deaths, of which five (0.90%) were due to mesothelioma; the rate of 46.2 per 100,000 subject-years was 3.5 times higher than among the local miners and millers. Six of the 33 cases in miners and millers were in men employed from 2 to 5 years and who might have been exposed to asbestos elsewhere; otherwise, the 22 cases at Thetford were in men employed 20 years or more and the five at Asbestos for at least 30 years. The cases at Thetford were more common in miners than in millers, whereas those at. Asbestos were all in millers. Within Thetford Mines, case-referent analyses showed a substantially increased risk associated with years of employment in a circumscribed group of five mines (Area A), but not in a peripherally distributed group of ten mines (Area B); nor was the risk related to years employed at Asbestos, either at the mine and mill or at the factory. There was no indication that risks were affected by the level of dust exposure. A similar pattern in the prevalence of pleural calcification had been observed at Thetford Mines in the 1970s. These geographical differences, both within the Thetford region and between it and Asbestos, suggest that the explanation is mineralogical. Lung tissue analyses showed that the concentration of

  8. 76 FR 39251 - Airworthiness Directives; The Boeing Company Model DC-9-81 (MD-81), DC-9-82 (MD-82), DC-9-83 (MD...

    Science.gov (United States)

    2011-07-06

    ... Model DC-9-81 (MD- 81), DC-9-82 (MD-82), DC-9-83 (MD-83), DC-9-87 (MD-87), and MD-88 Airplanes AGENCY... Jersey Avenue, SE., Washington, DC 20590. FOR FURTHER INFORMATION CONTACT: Roger Durbin, Aerospace.... Applicability (c) This AD applies to all The Boeing Company Model DC-9-81 (MD- 81), DC-9-82 (MD-82), DC-9-83...

  9. 76 FR 1993 - Airworthiness Directives; The Boeing Company Model DC-9-81 (MD-81), DC-9-82 (MD-82), DC-9-83 (MD...

    Science.gov (United States)

    2011-01-12

    ... Model DC-9-81 (MD- 81), DC-9-82 (MD-82), DC-9-83 (MD-83), DC-9-87 (MD-87), and MD-88 Airplanes AGENCY... Ground Floor, Room W12-140, 1200 New Jersey Avenue, SE., Washington, DC 20590. FOR FURTHER INFORMATION.... Applicability (c) This AD applies to The Boeing Company Model DC-9-81 (MD-81), DC-9-82 (MD-82), DC-9-83...

  10. 76 FR 13543 - Airworthiness Directives; The Boeing Company Model DC-9-81 (MD-81), DC-9-82 (MD-82), DC-9-83 (MD...

    Science.gov (United States)

    2011-03-14

    ... Model DC-9-81 (MD- 81), DC-9-82 (MD-82), DC-9-83 (MD-83), DC-9-87 (MD-87), and MD-88 Airplanes AGENCY... Floor, Room W12-140, 1200 New Jersey Avenue, SE., Washington, DC 20590. Hand Delivery: Deliver to Mail... stabilizer is similar in design and loading to that of the Model DC-9-81 (MD-81), DC- 9-82 (MD-82),...

  11. Cavity Voltage Phase Modulation MD

    CERN Document Server

    Mastoridis, Themistoklis; Molendijk, John; Timko, Helga; CERN. Geneva. ATS Department

    2016-01-01

    The LHC RF/LLRF system is currently configured for extremely stable RF voltage to minimize transient beam loading effects. The present scheme cannot be extended beyond nominal beam current since the demanded power would exceed the peak klystron power and lead to saturation. A new scheme has therefore been proposed: for beam currents above nominal (and possibly earlier), the cavity phase modulation by the beam will not be corrected (transient beam loading), but the strong RF feedback and One-Turn Delay feedback will still be active for loop and beam stability in physics. To achieve this, the voltage set point will be adapted for each bunch. The goal of this MD was to test a new algorithm that would adjust the voltage set point to achieve the cavity phase modulation that would minimize klystron forward power.

  12. Writing, Teaching, and Researching: An Interview with Rene Saldana, Jr.

    Science.gov (United States)

    Saldana, Rene, Jr.; Moore, David W.

    2010-01-01

    Rene Saldana, Jr., an assistant professor at Texas Tech University, is a writer of short stories, poetry, and novels. In order to get his storytelling right, he has relied on his memory when writing memoirs and consulted popular culture and family when writing fiction. In order to get his university teaching right, he reads seminal texts on…

  13. Martin Luther King, Jr.: The Dream of Peaceful Revolution.

    Science.gov (United States)

    Rowland, Della

    This biography for younger readers depicts the life of Martin Luther King, Jr., the Nobel Peace Prize winner who dedicated himself to the struggle for equal rights for African Americans while embracing the principle of nonviolent resistance. The book presents an overview of the civil rights movement and chronicles King's role as national leader…

  14. Celebrate the legacy of Dr. Martin Luther King Jr.

    OpenAIRE

    Lazenby, Jenna

    2006-01-01

    In celebration of the life and legacy of Dr. Martin Luther King, Jr., Virginia Tech will host a variety of educational and cultural programs and community service events Jan. 14-19, 2007. All events are free and open to the public.

  15. A Conservation with...Henry Louis Gates, Jr.

    Science.gov (United States)

    Cheney, Lynne V.

    1991-01-01

    Presents an interview between National Endowment for the Humanities chairman, Lynne V. Cheney, and Harvard professor, Henry Louis Gates, Jr. Includes discussion of multiculturalism as it relates to free speech, sexism, racism, hate speech, and ethnocentrism. Emphasizes both the open tradition of Western culture and the recent pressure for…

  16. Celebrate the legacy of Dr. Martin Luther King Jr.

    OpenAIRE

    Lazenby, Jenna

    2006-01-01

    In celebration of the life and legacy of Dr. Martin Luther King, Jr., Virginia Tech will host a variety of educational and cultural programs and community service events Jan. 14-19, 2007. All events are free and open to the public.

  17. Henry David Thoreau and Martin Luther King, Jr. Lesson Plan.

    Science.gov (United States)

    Powell, Brent

    1995-01-01

    Presents a five-lesson, high school instructional unit on the ideas and activities of Henry David Thoreau and Martin Luther King, Jr. Includes student objectives, step-by-step instructional procedures, and discussion questions. Provides quotations by Thoreau and King. (CFR)

  18. Dr. Martin Luther King, Jr. Washington State Resource Guide.

    Science.gov (United States)

    Washington Office of the State Superintendent of Public Instruction, Olympia, WA. Div. of Instructional Programs and Services.

    The Washington State Resource Guide on Martin Luther King, Jr., supplies a wide variety of materials for use with all grade levels in classroom and assembly presentations in public schools. The goal is for every child enrolled in Washington State schools to learn about Dr. King during the days of January 15 to January 17. Resolutions supporting an…

  19. Martin Luther King Jr.: The Crozer Seminary Years.

    Science.gov (United States)

    Carson, Clayborne

    1997-01-01

    As an undergraduate at Morehouse College, Martin Luther King Jr. was not a strong student, although he excelled in oratory, but in his years at Crozer Theological Seminary in Pennsylvania he applied himself to become a straight-A student. The development of his theological perspective is described. (SLD)

  20. A Dr. Martin Luther King, Jr. Curriculum: Playing the Dream.

    Science.gov (United States)

    Clemens, Sydney Gurewitz

    1988-01-01

    Discusses curriculum for young children centered around the beliefs and teachings of Dr. Martin Luther King, Jr. His works are interpreted in a human rights context in which children find their voice in the peaceable resolution of everyday conflicts. Describes the Child of the Day program. (Author/RWB)

  1. Finding the Right Formula: Edwin H. Walker Jr

    Science.gov (United States)

    Keels, Crystal L.

    2005-01-01

    Edwin H. Walker Jr earned his doctorate in chemistry at age 27 and has barely looked back. With 13 publications under his belt before coming out of graduate school, he has also given more than 20 poster presentations in national venues, most recently at the American Chemical Society. He can also include securing a half-million-dollar National…

  2. Sound Employment in the Adapted Movie-Daisy Miller

    Institute of Scientific and Technical Information of China (English)

    钦白兰

    2009-01-01

    Daisy Miller is a 1974 Ameriean drama movie directed by Peter Bogdanovich.It iS an adaptation of the Henry James‘novella of the same name.The movie,conmimng many symbolic cinematic techniques,iS about a beautiful young American girl died of"Roman fever"in Europe.This paper is devoted to the cinematic sound employment in the movie-Daisy Miller,with a purpose to show how the movie employs different sounds,difierent from the novella.to activate its theme.From the cinematic sound perspective,the paper claims that as all adapted movie,cinematic sound employment deeps the thematic realization,subtly intriguing with James,for the audience.

  3. Lee Miller, une battante sur tous les fronts

    Directory of Open Access Journals (Sweden)

    Anaïs Boutot

    2009-06-01

    Full Text Available L’art photographique de Lee Miller, à l’image de sa vie, revêt de multiples facettes. Après avoir été devant l’objectif en tant que mannequin puis égérie du Paris surréaliste, elle passe derrière l’objectif pour devenir photographe de mode, reporter de guerre ou encore portraitiste. L’exposition L’Art de Lee Miller, présentée au Jeu de Paume du 21 octobre 2008 au 4 janvier 2009 et accompagnée d’un ouvrage paru en français chez Hazan mettait en avant une quête d’identité et d’indépendance qui ...

  4. Petrography and Geochemistry of Lunar Meteorite Miller Range 13317

    Science.gov (United States)

    Zeigler, R. A.; Korotev, R. L.

    2016-01-01

    Miller Range (MIL) 13317 is a 32-g lunar meteorite collected during the 2013-2014 ANSMET (Antarctic Search for Meteorites) field season. It was initially described as having 25% black fusion crust covering a light- to dark-grey matrix, with numerous clasts ranging in size up to 1 cm; it was tenta-tively classified as a lunar anorthositic breccia. Here we present the petrography and geochemistry of MIL 13317, and examine possible pairing relationships with previously described lunar meteorites.

  5. Character Contrast in Arthur Miller s Death of a Salesman

    Institute of Scientific and Technical Information of China (English)

    程欣

    2007-01-01

    "I regard the theater as a serious business, one that makes or should make man more human, which is to say, less alone."A great playwright of social philosophy, Arthur Miller advocates that the common man, and none of rank, is the tragic hero of modern times. His plays have always revealed before the public eyes the tragedy of the average American life, the psychology of the ordinary people, and their conflicts with the morality of society.

  6. Takotsubo cardiomyopathy associated with Miller-Fisher syndrome.

    Science.gov (United States)

    Gill, Dalvir; Liu, Kan

    2017-07-01

    51-year-old female who presented with progressive paresthesia, numbness of the lower extremities, double vision, and trouble walking. Physical exam was remarkable for areflexia, and ptosis. Her initial EKG showed nonspecific ST segment changes and her Troponin T was elevated to 0.41ng/mL which peaked at 0.66ng/mL. Echocardiogram showed a depressed left ventricular ejection fraction to 35% with severely hypokinetic anterior wall and left ventricular apex was severely hypokinetic. EMG nerve conduction study showed severely decreased conduction velocity and prolonged distal latency in all nerves consistent with demyelinating disease. She was treated with 5days of intravenous immunoglobulin therapy to which she showed significant improvement in strength in her lower extremities. Echocardiogram repeated 4days later showing an improved left ventricular ejection fraction of 55% and no left ventricular wall motion abnormalities. Takotsubo cardiomyopathy is a rare complication of Miller-Fisher syndrome and literature review did not reveal any cases. Miller-Fisher syndrome is an autoimmune process that affects the peripheral nervous system causing autonomic dysfunction which may involve the heart. Due to significant autonomic dysfunction in Miller-Fisher syndrome, it could lead to arrhythmias, blood pressure changes, acute coronary syndrome and myocarditis, Takotsubo cardiomyopathy can be difficult to distinguish. The treatment of Takotsubo cardiomyopathy is supportive with beta-blockers and angiotensin-converting enzyme inhibitors are recommended until left ventricle ejection fraction improvement. Takotsubo cardiomyopathy is a rare complication during the acute phase of Miller-Fisher syndrome and must be distinguished from autonomic dysfunction as both diagnoses have different approaches to treatment. Published by Elsevier Inc.

  7. Topological modular forms (aftern Hopkins, Miller, and Lurie)

    CERN Document Server

    Goerss, Paul G

    2009-01-01

    This is the companion article to the Bourbaki talk of the same name given in March 2009. The main theme of the talk and the article is to explain the interplay between homotopy theory and algebraic geometry through the Hopkins-Miller-Lurie theorem on topological modular forms, from which we learn that the Deligne-Mumford moduli stack for elliptic curves is canonically realized as an object in derived algebraic geometry.

  8. THE MILLER OPERATIONAL AMPLIFIER’S SETTLING RESPONSE

    Directory of Open Access Journals (Sweden)

    E. Ruíz-May

    2007-08-01

    Full Text Available This paper presents a third-order transfer function to model the settling response of the Miller operationalamplifier. The amplifier was simulated (spice and designed according to design rules of a standard 1.5μmCMOS fabrication process. The proposed mathematical model -based on design parameters under thedesigner’s control- is the best settling approach reported up to now

  9. On the Attraction of Matter by the Ponderomotive Miller Force

    CERN Document Server

    Lundin, Rickard

    2010-01-01

    Wave induced attraction of matter is a unique aspect of ponderomotive forcing by electromagnetic (e/m) waves in plasmas. The Miller force, sometimes denoted the gradient force, is of particular interest, because the direction as well as magnitude of the Miller force on a plasma depends on the wave frequency. While plasma is usually considered in its gaseous form, solid bodies can also be treated as plasma, denoted solid-state plasma. The first experimental proof of wave effects in magnetized solid-state plasmas (Lundqvist, 1949, Herlofson, 1950) came after the suggestion by Alfv\\'en (1942) on the possible existence of magneto-hydrodynamic (MHD) waves. However, most of our knowledge basis on MHD/Alfv\\'en waves have since then emerged from space- and laboratory (gaseous) plasmas. It is therefore timely to investigate further the applicability of e/m wave ponderomotive forcing on solid-state plasma. In this report we discuss the applicability of the ponderomotive Miller force on solid-state plasmas. At this stag...

  10. Hybrid Automotive Engine Using Ethanol-Burning Miller Cycle

    Science.gov (United States)

    Weinstein, Leonard

    2004-01-01

    A proposed hybrid (internal-combustion/ electric) automotive engine system would include as its internal-combustion subsystem, a modified Miller-cycle engine with regenerative air preheating and with autoignition like that of a Diesel engine. The fuel would be ethanol and would be burned lean to ensure complete combustion. Although the proposed engine would have a relatively low power-to-weight ratio compared to most present engines, this would not be the problem encountered if this engine were used in a non-hybrid system since hybrid systems require significantly lower power and thus smaller engines than purely internal-combustion-engine-driven vehicles. The disadvantage would be offset by the advantages of high fuel efficiency, low emission of nitrogen oxides and particulate pollutants, and the fact that ethanol is a renewable fuel. The original Miller-cycle engine, named after its inventor, was patented in the 1940s and is the basis of engines used in some modern automobiles, but is not widely known. In somewhat oversimplified terms, the main difference between a Miller-cycle engine and a common (Otto-cycle) automobile engine is that the Miller-cycle engine has a longer expansion stroke while retaining the shorter compression stroke. This is accomplished by leaving the intake valve open for part of the compression stroke, whereas in the Otto cycle engine, the intake valve is kept closed during the entire compression stroke. This greater expansion ratio makes it possible to extract more energy from the combustion process without expending more energy for compression. The net result is greater efficiency. In the proposed engine, the regenerative preheating would be effected by running the intake air through a heat exchanger connected to the engine block. The regenerative preheating would offer two advantages: It would ensure reliable autoignition during operation at low ambient temperature and would help to cool the engine, thereby reducing the remainder of the

  11. Martin Luther King Jr. contest winning posters to be displayed in downtown Blacksburg

    OpenAIRE

    Shannon, Kelly Baker

    2010-01-01

    Each year as part of the Martin Luther King Jr. celebration at Virginia Tech area kindergarten through 12th grade students are invited to participate in the annual Martin Luther King Jr. poster contest.

  12. Fast Collision Attack on MD5

    NARCIS (Netherlands)

    M.M.J. Stevens (Marc)

    2006-01-01

    textabstractIn this paper, we present an improved attack algorithm to find two-block collisions of the hash function MD5. The attack uses the same differential path of MD5 and the set of sufficient conditions that was presented by Wang et al. We present a new technique which allows us to

  13. Fast Collision Attack on MD5

    NARCIS (Netherlands)

    Stevens, M.M.J.

    2006-01-01

    In this paper, we present an improved attack algorithm to find two-block collisions of the hash function MD5. The attack uses the same differential path of MD5 and the set of sufficient conditions that was presented by Wang et al. We present a new technique which allows us to deterministically fulfi

  14. Harvesting graphics power for MD simulations

    NARCIS (Netherlands)

    van Meel, J.A.; Arnold, A.; Frenkel, D.; Portegies Zwart, S.F.; Belleman, R.G.

    2008-01-01

    We discuss an implementation of molecular dynamics (MD) simulations on a graphic processing unit (GPU) in the NVIDIA CUDA language. We tested our code on a modern GPU, the NVIDIA GeForce 8800 GTX. Results for two MD algorithms suitable for short-ranged and long-ranged interactions, and a congruentia

  15. First thoughts on MD priorities for 2012

    CERN Document Server

    Zimmermann, F; Assmann, R

    2012-01-01

    In 2012, 22 days of beam time will be allocated for LHC MDs. In this paper, after recalling the 2011 LHC MD experience, the MD rrequests for 2012 are reviewed. Three primary MD themes for 2012 can be identified: 1)pushing performance in 2012, 2)preparing for 2014/15, and 3)towards maximum luminosity. Example topics include emittance growth in collision or enhanced satellites for theme 1), 25 ns operation for 2), and ATS optics for 3). Structures lists of MD requests and topics for each theme as well as some initial thoughts on the MD priorities are presented. For certain topics, "start-of-fill MDs" are proposed in order to most efficiently use of the available beam time.

  16. 76 FR 52225 - Airworthiness Directives; The Boeing Company Model DC-9-81 (MD-81), DC-9-82 (MD-82), DC-9-83 (MD...

    Science.gov (United States)

    2011-08-22

    ... Model DC-9-81 (MD- 81), DC-9-82 (MD-82), DC-9-83 (MD-83), DC-9-87 (MD-87), and MD-88 Airplanes AGENCY... Ground Floor, Room W12-140, 1200 New Jersey Avenue, SE., Washington, DC 20590. FOR FURTHER INFORMATION... ADs (b) None. Applicability (c) This AD applies to The Boeing Company Model DC-9-81 (MD-81),...

  17. Dr. John H. Hopps Jr. Research Scholars Program

    Science.gov (United States)

    2014-10-20

    graduates’ majors, honors/awards and their acceptance to a doctoral program. Also, assisting with securing the keynote speaker, Dr. Jimmie Lee Davis, Jr...experiences during school semesters and in the summers, and scholastic information such as college majors, minors, graduations, degree pursuits, fellowships...climate change. The Morehouse Hopps Alumni Panel included seven graduates who are currently in various levels of graduate school. Their candid

  18. Obituary: Benjamin Franklin Peery Jr. (1922-2010)

    Science.gov (United States)

    Cowley, Charles

    2011-12-01

    Professor Benjamin F. Peery, Jr. died at his home in Silver Spring, MD of natural causes on 30 November 2010. His full life began in St. Joseph, MO (home of the Pony Express) on 4 March 1922. His father was a railway mail clerk, so his family moved frequently. Most of his childhood was spent in southeastern Minnesota. He enlisted in the army in 1942, and served in campaigns in North Africa and Italy. After his discharge in 1945, he enrolled in the University of Minnesota, earning a BS in Physics in 1949. One of his early hobbies was to build and fly model airplanes. His intention to pursue aeronautical engineering changed to physics, but after receiving a MS in physics from Fisk University in 1955, he decided on a career in astronomy. He told the editors of the PBS series The Astronomers (1991, in which his career is highlighted) he thought it was shamefully absurd not to know what made the stars shine. So he began PhD studies in astronomy at the University of Michigan (Ann Arbor). His dissertation was on the complex eclipsing binary VV Cephei, where a compact hot star passes behind a cool giant star, revealing the structure of that giant's atmosphere. This task was especially demanding because of the complexity of the system's spectrum and the formidable array of observations assembled by Ben's advisor, Dean McLaughlin. Fortunately, Ben's strong physics background enabled him to design and construct one of the first oscilloscope measuring engines, which his fellow students called the PeeryScope. The final (1961) dissertation is an impressive combination of observational and astrophysical analysis. His degree was obtained in 1962; he had already begun a career at the University of Indiana, where he taught and did research (1959--1976). The Indiana years were highly productive. In addition to his own research, he was advisor on six PhD dissertations, and a master's thesis. Several of his students have also had productive careers. An ADS search on his students' names

  19. Myxomycetes on carnaubeira (Copernicia prunifera (Miller) H. E. Moore, Arecaceae)

    OpenAIRE

    Mobin,Mitra; Cavalcanti, Laise de Holanda

    2000-01-01

    Entre dezembro/1994 e setembro/1995 foram realizadas sete excursões (2 a 4 dias cada) ao Parque Nacional de Sete Cidades (4º5'-4º15'S, 41º30'-41º40'W, 450m alt.), em Piripiri, Piauí, visando coletar frutificações de Myxomycetes em indivíduos de Coperniciaprunifera (Miller) H. E. Moore, estabelecidos em área de cerrado, na localidade Lagoa Seca. As amostras foram herborizadas e incorporadas ao herbário UFP (Universidade Federal de Pernambuco, Recife, PE), com duplicatas no herbário TEPB (Unive...

  20. Character Contrast in Arthur Miller's Death of a Salesman

    Institute of Scientific and Technical Information of China (English)

    程欣

    2007-01-01

      "I regard the theater as a serious business,one that makes or should make man more human,which is to say,less alone."A great playwright of social philosophy,Arthur Miller advocares that the common man,and none of rank,is the tragic hero of modern times.His plays have always revealed before the public eyes the tragedy of the average American life,the psychology of the ordinary people,and their conflicts with the morality of society.……

  1. Transmission probabilities and the Miller-Good transformation

    CERN Document Server

    Boonserm, Petarpa

    2008-01-01

    Transmission through a potential barrier, and the related issue of particle production from a parametric resonance, are topics of considerable general interest in quantum physics. The authors have developed a rather general bound on quantum transmission probabilities, and recently applied it to bounding the greybody factors of a Schwarzschild black hole. In the current article we take a different tack -- we use the Miller-Good transformation (which maps an initial Schrodinger equation to a final Schrodinger equation for a different potential) to significantly generalize the previous bound.

  2. A Case of Neuromyelitis Optica Masquerading as Miller Fisher Syndrome

    Directory of Open Access Journals (Sweden)

    Yuka Furutani

    2014-10-01

    Full Text Available A 22-year-old woman presented with double vision that she had experienced since an infection 2 weeks previously. A neurological examination showed limited bilateral eye abduction, mimicking Miller Fisher syndrome. However, T2-weighted magnetic resonance imaging of her brain revealed hyperintense areas in the tegmentum of the pons, including the abducens nucleus, and her serum anti-aquaporin-4 antibody test was positive. She was finally diagnosed with neuromyelitis optica. Intravenous high-dose steroid therapy immediately improved the patient's abduction palsy, but bilateral optic neuritis manifested during the treatment. Subsequent treatment with plasma exchange improved her optic neuritis symptoms.

  3. A Tragedy of a Common Man in Arthur Miller's Death of a Salesman

    Institute of Scientific and Technical Information of China (English)

    梁花

    2009-01-01

    @@ 1. Arthur Miller and Death of a Salesman 1.1 Arthur Miller,One of the Greatest American Playwrights of the Twentieth Century Arthur Miller was one of the most preeminent playwrights of the twentieth century and one of America's most distinguished men of letters.He was born in October of 1915 in New York City. His plays continued the realistic tradition that began in the United States in the period between the two World Wars.

  4. Myxomycetes on carnaubeira (Copernicia prunifera (Miller) H. E. Moore, Arecaceae) Myxomycetes em carnaubeira (Copernicia prunifera (Miller) H. E. Moore, Arecaceae)

    OpenAIRE

    Mitra Mobin; Laise de Holanda Cavalcanti

    2000-01-01

    Entre dezembro/1994 e setembro/1995 foram realizadas sete excursões (2 a 4 dias cada) ao Parque Nacional de Sete Cidades (4º5'-4º15'S, 41º30'-41º40'W, 450m alt.), em Piripiri, Piauí, visando coletar frutificações de Myxomycetes em indivíduos de Coperniciaprunifera (Miller) H. E. Moore, estabelecidos em área de cerrado, na localidade Lagoa Seca. As amostras foram herborizadas e incorporadas ao herbário UFP (Universidade Federal de Pernambuco, Recife, PE), com duplicatas no herbário TEPB (Unive...

  5. Amending Miller's Pyramid to Include Professional Identity Formation.

    Science.gov (United States)

    Cruess, Richard L; Cruess, Sylvia R; Steinert, Yvonne

    2016-02-01

    In 1990, George Miller published an article entitled "The Assessment of Clinical Skills/Competence/Performance" that had an immediate and lasting impact on medical education. In his classic article, he stated that no single method of assessment could encompass the intricacies and complexities of medical practice. To provide a structured approach to the assessment of medical competence, he proposed a pyramidal structure with four levels, each of which required specific methods of assessment. As is well known, the layers are "Knows," "Knows How," "Shows How," and "Does." Miller's pyramid has guided assessment since its introduction; it has also been used to assist in the assessment of professionalism.The recent emphasis on professional identity formation has raised questions about the appropriateness of "Does" as the highest level of aspiration. It is believed that a more reliable indicator of professional behavior is the incorporation of the values and attitudes of the professional into the identity of the aspiring physician. It is therefore proposed that a fifth level be added at the apex of the pyramid. This level, reflecting the presence of a professional identity, should be "Is," and methods of assessing progress toward a professional identity and the nature of the identity in formation should be guided by currently available methods.

  6. Obituary of Philip H. Cooper, MD.

    Science.gov (United States)

    Patterson, James W; Wick, Mark R; Mills, Stacey E

    2015-08-01

    Dermatopathology lost a giant in the field with the death of Philip H. Cooper, MD, on Friday, January 30, 2015. The following obituary represents a celebration of his life and his contributions to our field.

  7. LANSCE '90: The Manuel Lujan Jr. Neutron Scattering Center

    Energy Technology Data Exchange (ETDEWEB)

    Pynn, R.

    1990-01-01

    This paper describes progress that has been made at the Manuel Lujan Jr. Neutron Scattering Center (LANSCE) during the past two years. Presently, LANSCE provides a higher peak neutron flux than any other pulsed spallation neutron source. There are seven spectrometers for neutron scattering experiments that are operated for a national user program sponsored by the US Department of Energy. Two more spectrometers are under construction. Plans have been made to raise the number of beam holes available for instrumentation and to improve the efficiency of the target/moderator system. 9 refs., 4 figs.

  8. Martin Luther King, Jr., General Hospital and community involvement.

    Science.gov (United States)

    Humphrey, M M

    1973-07-01

    Community involvement is not just one facet of the new Martin Luther King, Jr., General Hospital's existence. It is the mainstream from which all other activities flow. In addition to meeting the conventional needs of a conventional hospital staff with the core collection of texts and journals, this library goes one step further. It acts as a resource for its community health workers, dietitians, and nurses in their various outreach programs. It serves as a stimulus for the high school or community college student who may be curious about a health career. It also finds time to provide reading material for its patients.

  9. Mancur Lloyd Olson, Jr. 1932-1998 Personal Recollections

    OpenAIRE

    Martin C McGuire

    1998-01-01

    This article memorializes the life and professional work of Mancur Lloyd Olson, Jr. The forty-two years of Mancur Olson's scholarly life were devoted to an inspiring pursuit of his vision of "macro." His ideas may occupy the core of macroeconomics fifty or one hundred years from now, or they may signify only one strand, but surely they will be present and influential in all future study of economics, of society and of interactions between them. Here in 1998, we don't know. But we do know that...

  10. Investigating the Skoog-Miller Model for Organogenesis Using Sweet Potato Root Explants.

    Science.gov (United States)

    Delany, William; And Others

    1994-01-01

    Describes an experiment in which groups of students in a plant tissue culture course worked together to test application of the Skoog-Miller model (developed by Skoog and Miller in regeneration of tobacco experiments to demonstrate organogenesis) to sweet potato root explants. (ZWH)

  11. Maslow and Miller: An Exploration of Gender and Affiliation in the Journey to Competence

    Science.gov (United States)

    Coy, Doris Rhea; Kovacs-Long, Judith

    2005-01-01

    This article shows that although neither Abraham Maslow nor Jean Baker Miller reference each other in their writings, they are following different paths to the same conclusion: competence proceeds from connection. Miller and Maslow both describe a developmental model that applies equally to women and men. The conclusion of the authors of this…

  12. Investigating the Skoog-Miller Model for Organogenesis Using Sweet Potato Root Explants.

    Science.gov (United States)

    Delany, William; And Others

    1994-01-01

    Describes an experiment in which groups of students in a plant tissue culture course worked together to test application of the Skoog-Miller model (developed by Skoog and Miller in regeneration of tobacco experiments to demonstrate organogenesis) to sweet potato root explants. (ZWH)

  13. Does Morality Harm Children? Alice Miller on Morality and Poisonous Pedagogy

    Science.gov (United States)

    Fridley, William L.

    2006-01-01

    Alice Miller, the former psychoanalyst, has gained world renown for her controversial and provocative writings on child rearing. Miller contends that traditional child rearing practices--in schools, ecclesiastical settings, and the family--consist of physical and emotional cruelty that she labels "poisonous pedagogy." According to…

  14. 48 CFR 3052.228-90 - Notification of Miller Act payment bond protection (USCG).

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Notification of Miller Act... Act payment bond protection (USCG). As prescribed in USCG guidance at (HSAR) 48 CFR 3028.106-490, insert the following clause: Notification of Miller Act Payment Bond Protection (DEC 2003) This...

  15. 33 CFR 110.79b - Millers Bay, Lake Winnebago, Oshkosh, WI

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Millers Bay, Lake Winnebago, Oshkosh, WI 110.79b Section 110.79b Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND..., Oshkosh, WI The area adjacent to Menominee Park in Millers Bay within the following boundaries:...

  16. MILLS B. LANE, JR. AND ENTERPRISE IN A NEW SOUTH

    Directory of Open Access Journals (Sweden)

    Randall L. Patton

    2009-01-01

    Full Text Available For a century, Citizens & Southern Bank was a fixture in Georgia. In 1991, the C&S brand name disappeared in a merger with North Carolina National Bank. This was one of the bittersweet consequences of the slow, confusing swirl of bank deregulation after 1970, when institutions such as C&S simply disappeared, swallowed by the “winners” in the new competitive environment of interstate banking in the 1980s and 1990s. Even earlier, however, the Lane family had ceased to control the bank started by Mills Lane, Sr. in 1891. Mills B. Lane, Jr. was the last member of the Lane family to run C&S. After his retirement in 1973, Mills handpicked his successor and tried to retain some influence, but the bank began slipping away from the Lanes. By the early 80s, a decade before Hugh McColl’s NCNB acquired C&S, Mills Lane, Jr. was deeply alienated from the institution that had been, according to many, “Georgia’s cornerstone bank.”

  17. A new nearby PWN overlapping the Vela Jr SNR

    CERN Document Server

    Acero, F; Terrier, R; Renaud, M; Ballet, J

    2011-01-01

    PSR J0855-4644 is an energetic pulsar (Edot = 1.1x10^36 erg/s, P=65 ms) discovered near the South-East rim of the supernova remnant (SNR) RX J0852.0-4622 (aka Vela Jr) by the Parkes Multibeam Survey. The position of the pulsar is in spatial coincidence with an enhancement in X-rays and TeV gamma-rays, which could represent its pulsar wind nebula (PWN). We have revealed with an XMM-Newton observation the X-ray counterpart of the pulsar together with a surrounding extended emission thus confirming the suggestion of a PWN. The comparison of the absorption column density derived in X-rays from the pulsar with 12CO observations (tracing the dense gas) is used to derive an upper limit to the distance of the pulsar (d< 900 pc) and to discuss a possible association of the pulsar with the Vela Jr SNR. This new distance estimate implies that the pulsar is nearby and could therefore significantly contribute to the observed spectrum of cosmic-ray leptons (e-/e+).

  18. Formation of nucleobases in a Miller-Urey reducing atmosphere.

    Science.gov (United States)

    Ferus, Martin; Pietrucci, Fabio; Saitta, Antonino Marco; Knížek, Antonín; Kubelík, Petr; Ivanek, Ondřej; Shestivska, Violetta; Civiš, Svatopluk

    2017-04-25

    The Miller-Urey experiments pioneered modern research on the molecular origins of life, but their actual relevance in this field was later questioned because the gas mixture used in their research is considered too reducing with respect to the most accepted hypotheses for the conditions on primordial Earth. In particular, the production of only amino acids has been taken as evidence of the limited relevance of the results. Here, we report an experimental work, combined with state-of-the-art computational methods, in which both electric discharge and laser-driven plasma impact simulations were carried out in a reducing atmosphere containing NH3 + CO. We show that RNA nucleobases are synthesized in these experiments, strongly supporting the possibility of the emergence of biologically relevant molecules in a reducing atmosphere. The reconstructed synthetic pathways indicate that small radicals and formamide play a crucial role, in agreement with a number of recent experimental and theoretical results.

  19. Biofunctional properties of Eruca sativa Miller (rocket salad) hydroalcoholic extract.

    Science.gov (United States)

    Sultan, Khushbakht; Zakir, Muhammad; Khan, Haroon; Rauf, Abdur; Akber, Noor Ul; Khan, Murad Ali

    2016-01-01

    Eruca sativa Miller is a worldwide common alimentary plant (rocket leaves). The aim of this study was to correlate the potential in vitro scavenging activity of the E. sativa hydroalcoholic extract (HAE) with its in vivo hypoglycaemic effect. In DDPH free radical (DFR) and ferric-reducing antioxidant power assays, HAE in a concentration dependent manner (25-100 μg/mL) displayed a strong scavenging activity with maximum effect of 88% and 75% at 100 μg/mL, respectively. Daily administration of HAE (50 mg/kg; p.o.) in the in vivo model of alloxan-induced diabetic rabbits for 28 days showed significant reduction in glycaemia, also supported by recovery of body weight. In conclusion, our results give preliminary information on the potential use of this plant as a nutraceutical, useful to control and/or prevent a hyperglycaemic status.

  20. Karp-Miller Trees for a Branching Extension of VASS

    Directory of Open Access Journals (Sweden)

    Kumar Neeraj Verma

    2005-12-01

    Full Text Available We study BVASS (Branching VASS which extend VASS (Vector Addition Systems with States by allowing addition transitions that merge two configurations. Runs in BVASS are tree-like structures instead of linear ones as for VASS. We show that the construction of Karp-Miller trees for VASS can be extended to BVASS. This entails that the coverability set for BVASS is computable. This allows us to obtain decidability results for certain classes of equational tree automata with an associative-commutative symbol. Recent independent work by de Groote et al. implies that decidability of reachability in BVASS is equivalent to decidability of provability in MELL (multiplicative exponential linear logic, which is still an open problem. Hence our results are also a step towards answering this question in the affirmative.

  1. Miller-Fisher syndrome associated with chronic lymphocytic leukemia

    Directory of Open Access Journals (Sweden)

    Aki Zeynep

    2008-01-01

    Full Text Available Chronic lymphocytic leukemia (CLL is a frequent hematological malignancy, with meningeal or peripheral nerve infiltrations being the most commonly encountered neurological complications. In this report, we describe a CLL patient with Miller-Fisher syndrome (MFS who responded to immune modulation with plasmapheresis. A 47-year-old man diagnosed as B-cell CLL admitted with neutropenic fever. He complained of diplopia and numbness of both arms. Neurological examination revealed a bilateral external ophthalmoplegia, dysphagia, dysarthria, mild shoulder girdle muscle weakness and gait ataxia, accompanied by absent tendon reflexes. Nerve conduction studies were indicative of a predominantly axonal sensori-motor peripheral neuropathy. This association of CLL with MFS had not been previously reported in the literature.

  2. George A. Miller, language, and the computer metaphor of mind.

    Science.gov (United States)

    Crowther-Heyck, H

    1999-02-01

    This article asks why the analogy between humans and computers was understood by cognitive psychologists to mean that "minds exist and that it is our job as psychologists to study them". Earlier psychologists, such as Clark Hull, used analogies between humans and complex machines such as telephone switchboards to defend a rigorous behaviorism. How, then, did the computer metaphor of mind come to be seen as the root concept underlying a paradigm shift from behaviorism to cognitivism? To answer this question, this article examines the life and work of George A. Miller, one of the most prominent of a generation of psychologists who began their careers as "good behaviorists" but later came to embrace cognitivism.

  3. Pollen Morphology of Acinos Miller Species Growing in Turkey

    Institute of Scientific and Technical Information of China (English)

    Ayla Kaya; Hatice Kutluk

    2007-01-01

    The pollen morphology of six taxa of the genus Acinos Miller has been examined under scanning electron microscopy(SEM) and a description of each taxon has been given. Acinos pollen is stephanocolpate (hexacolpate). Two main exine sculpturing types, foveolate-reticulate (only in subspecies of A. troodi) and reticulate have been defined. The dimension for the polar length ranges between 25.8-47.4 μm, equatorial width 24.5-34.4 μm, colpus length 20.0-40.5 μm and colpus width 1.2-2.5 μm. The shape is mostly subprolate to prolate, seldomly prolate-spheroidal. The results reveal rather uniform morphological features, however fine details are characteristic to differentiate the pollen taxa. Acinos pollen also share some common morphological features with the other Lamiaceae pollen.

  4. MD5算法的分析和改进%Analysis and Improvement of .MD5 Algorithm

    Institute of Scientific and Technical Information of China (English)

    么丽颖

    2011-01-01

    首先研究了MD5算法,并总结了MD5算法的特点及性能,在研究MD5算法的基础之上,提出了MD5改进加密算法.最后,对MD5算法与MD5改进算法对应于相关数据、性能进行了比较.%At first , MD5 algorithm is researched, and the characteristic and capability of the MD5 are summaried in the paper. The improved MD5 algorithm is put forward based on the research of the MDS. At last, the contrast between MD5 algorithm and the improved MD5 algorithm in related datum and capability are put forward.

  5. New Message Differences for Collision Attacks on MD4 and MD5

    Science.gov (United States)

    Sasaki, Yu; Wang, Lei; Kunihiro, Noboru; Ohta, Kazuo

    In 2005, collision resistance of several hash functions was broken by Wang et al. The strategy of determining message differences is the most important part of collision attacks against hash functions. So far, many researchers have tried to analyze Wang et al.'s method and proposed improved collision attacks. Although several researches proposed improved attacks, all improved results so far were based on the same message differences proposed by Wang et al. In this paper, we propose new message differences for collision attacks on MD4 and MD5. Our message differences of MD4 can generate a collision with complexity of less than two MD4 computations, which is faster than the original Wang et al.'s attack, and moreover, than the all previous attacks. This is the first result that improves the complexity of collision attack by using different message differences from Wang et al.'s. Regarding MD5, so far, no other message difference from Wang et al.'s is known. Therefore, study for constructing method of other message differences on MD5 should be interesting. Our message differences of MD5 generates a collision with complexity of 242 MD5 computations, which is slower than the latest best attack. However, since our attack needs only 1 bit difference, it has some advantages in terms of message freedom of collision messages.

  6. William T. Carpenter Jr: 35 years of clinical trials.

    Science.gov (United States)

    Buchanan, Robert W

    2014-03-01

    William T. Carpenter Jr has had a major impact on the design and conduct of clinical trials in schizophrenia. His contributions range from the decisive evaluation of the efficacy of hemodialysis to the development of novel approaches to evaluate new treatments for cognitive impairments and negative symptoms. He has developed innovative dosage reduction strategies. He has led efforts to focus drug development on those illness components that are not responsive to antipsychotic treatment. He has emphasized throughout his career the use of translational science to provide the conceptual framework for clinical trial interventions. This article reviews highlights of his many contributions, with an emphasis on 3 areas: (1) dosage reduction studies; (2) the use of the domains of psychopathology to identify drug development targets; and (3) the use of translational science to guide new drug development.

  7. Gino Marinuzzi Jr: Electronics and Early Multimedia Mentality in Italy

    Directory of Open Access Journals (Sweden)

    Maurizio Corbella

    2015-08-01

    Full Text Available In this essay I reassess the complexity of the convergence between electronic music and media practices in Rome in the 1950s and 1960s, through the reconstruction of the experience of composer Gino Marinuzzi Jr (1920-96. His engagement with technology as a structuring device of compositional processes is fundamental and inescapable, and brings to the fore crucial issues of ‘applied’ music’s troublesome reputation in the Italian cultural discourse. In reviewing Marinuzzi’s biography over the period 1949-75, my goal is to exemplify the key phases of this transitional period in Italian music history, in which technology, through the spreading of media and their increasing importance in cultural representations, came to constitute a new value of musical activity and at the same time renewed old questions concerning music’s aesthetic autonomy.

  8. Post project evaluation, Miller Creek, California : assessment of stream bed morphology, and recommendations for future study

    OpenAIRE

    Yin, Wan-chih; Pope-Daum, Caitilin

    2004-01-01

    Miller creek is located in Marin County, California, and runs east from Big Rock Ridge through the Laws Gallinas Valley and into the San Pablo Bay. The Miller Creek watershed has been grazed continuously since the 1800s, and the creek has experienced sever widening and down cutting as a result. The miller Creek restoration Project, located in the Lucas Valley Estates subdivision and designed and built from 1979 to 1989, employed a multi-stage channel approach to restore and protect a riparian...

  9. 76 FR 77579 - Maryland Disaster #MD-00017

    Science.gov (United States)

    2011-12-13

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Maryland Disaster MD-00017 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY... INFORMATION CONTACT: A. Escobar, Office of Disaster Assistance, U.S. Small Business Administration, 409...

  10. 78 FR 2707 - Maryland Disaster # MD-00026

    Science.gov (United States)

    2013-01-14

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Maryland Disaster MD-00026 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY... INFORMATION CONTACT: A. Escobar, Office of Disaster Assistance, U.S. Small Business Administration, 409...

  11. Claim on memory : a political biography of Franklin D. Roosevelt, Jr., 1914-1988

    NARCIS (Netherlands)

    Berg, Erik Eduard Willem van den

    2006-01-01

    This dissertation focuses on the political life of Franklin D. Roosevelt, Jr., the third surviving son of Franklin D. Roosevelt and Eleanor Roosevelt. The key question of this study emphasizes how FDR, Jr. interpreted the Roosevelt name and legacy during his life and political career. This book deal

  12. Connect the Book. Martin's Big Words: The Life of Dr. Martin Luther King, Jr.

    Science.gov (United States)

    Brodie, Carolyn S.

    2005-01-01

    In honor of Martin Luther King, Jr. Day, this month's featured book is "Martin's Big Words: The Life of Dr. Martin Luther King, Jr." The book was written by Doreen Rappaport and illustrated by Bryan Collier (Jump at the Sun, 2001. 40p. ISBN 0786807148). This pictorial biography of the world-renowned civil rights leader has one of the most striking…

  13. 78 FR 57105 - Wm. Wrigley Jr. Company; Filing of Color Additive Petition

    Science.gov (United States)

    2013-09-17

    ... HUMAN SERVICES Food and Drug Administration 21 CFR Part 73 Wm. Wrigley Jr. Company; Filing of Color.... Wrigley Jr. Company, proposing that the color additive regulations be amended to expand the use of... lower the specification limit ] for lead in synthetic iron oxide for human food use. DATES: The...

  14. Omphalocele in Miller-Dieker syndrome: Expanding the phenotype

    Energy Technology Data Exchange (ETDEWEB)

    Chitayat, D. [Toronto Hospital-General Division, Ontario (Canada)]|[Univ. of Toronto, Ontario (Canada); Moola, S.; Yarkoni, D. [Toronto Hospital-General Division, Ontario (Canada)] [and others

    1997-03-31

    We report on a patient prenatally diagnosed with omphalocele, mild cerebral ventriculomegaly, nuchal fold thickening, and cystic changes in the umbilical cord who was found postnatally to have lissencephaly type I. Prenatal chromosome analysis showed a normal male karyotype; however, postnatal high resolution banding and FISH analysis, using a probe for locus D17S379 in chromosome region 17p13.3, demonstrated a deletion at 17p13.3 consistent with Miller-Dieker syndrome (MDS). A review documented four more cases with MDS/isolated lissencephaly/17p-, with omphalocele. Because MDS is a contiguous gene disorder, we speculate that a gene or genes in this region have a major role in the closure of the lateral folds or the return of the midgut from the body stalk to the abdomen at 5-11 weeks of gestation. Prenatal diagnosis of omphalocele with mild ventriculomegaly should prompt FISH analysis for a deletion in 17p13.3. 44 refs., 7 figs., 1 tab.

  15. Larson-Miller Constant of Heat-Resistant Steel

    Science.gov (United States)

    Tamura, Manabu; Abe, Fujio; Shiba, Kiyoyuki; Sakasegawa, Hideo; Tanigawa, Hiroyasu

    2013-06-01

    Long-term rupture data for 79 types of heat-resistant steels including carbon steel, low-alloy steel, high-alloy steel, austenitic stainless steel, and superalloy were analyzed, and a constant for the Larson-Miller (LM) parameter was obtained in the current study for each material. The calculated LM constant, C, is approximately 20 for heat-resistant steels and alloys except for high-alloy martensitic steels with high creep resistance, for which C ≈ 30 . The apparent activation energy was also calculated, and the LM constant was found to be proportional to the apparent activation energy with a high correlation coefficient, which suggests that the LM constant is a material constant possessing intrinsic physical meaning. The contribution of the entropy change to the LM constant is not small, especially for several martensitic steels with large values of C. Deformation of such martensitic steels should accompany a large entropy change of 10 times the gas constant at least, besides the entropy change due to self-diffusion.

  16. Adaptation: a contemporary view, revisiting Crichton-Miller's 1925 paper.

    Science.gov (United States)

    Music, Graham

    2016-03-01

    In this paper I discuss a contemporary 'take' on the concept of adaptation in light of Crichton-Miller's original 1926 paper. I look briefly at some of the ways that contemporary thinking is both similar to and different from ideas of 90 years ago. In particular I think about how recent neurobiological findings, epigenetic research and attachment theory have cast new light on our understanding of the ways humans adapt to social and emotional environments. It looks at how psychiatric presentations which are seen as maladaptive might well have an adaptive origin in early life. In this account I emphasise how a more modern version of evolutionary theory can be developed, particularly one influenced by life history theory, and suggest that such ideas have powerful explanatory power as well as being based solidly in good research. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  17. Myxomycetes on carnaubeira (Copernicia prunifera (Miller H. E. Moore, Arecaceae Myxomycetes em carnaubeira (Copernicia prunifera (Miller H. E. Moore, Arecaceae

    Directory of Open Access Journals (Sweden)

    Mitra Mobin

    2000-04-01

    Full Text Available Entre dezembro/1994 e setembro/1995 foram realizadas sete excursões (2 a 4 dias cada ao Parque Nacional de Sete Cidades (4º5'-4º15'S, 41º30'-41º40'W, 450m alt., em Piripiri, Piauí, visando coletar frutificações de Myxomycetes em indivíduos de Coperniciaprunifera (Miller H. E. Moore, estabelecidos em área de cerrado, na localidade Lagoa Seca. As amostras foram herborizadas e incorporadas ao herbário UFP (Universidade Federal de Pernambuco, Recife, PE, com duplicatas no herbário TEPB (Universidade Federal do Piauí, Teresina, PI. Registrou-se apreciável incidência (70% de Myxomycetes na carnaubeira, em estipe vivo e folhas mortas. Dezesseis espécies, pertencentes às Ceratiomyxaceae (Ceratiomyxa lsp., Didymiaceae (Diachea lsp., Didymium 2spp., Physaraceae (Craterium 1sp., Physarum 4spp., Trichiaceae (Arcyria 2spp. e Stemonitaceae (Comatricha 3spp., Macbrideola lsp., Stemonitis lsp. foram registradas. Ceratiomyxaceae, representada por Ceratiomyxafruticulosa (Mull. Macbr., constitui primeira referência para o Estado do Piauí.From December, 1994 to September, 1995, seven collecting trips (2-4 days each were carried out in the "Parque Nacional de Sete Cidades" (4º5'-4º15'S, 41º30"-41º40'W, 450m alt., Piripiri, Piauí State, Brazil, in order to collect Myxomycetes fruiting bodies on carnauba palm trees (Coperniciaprunifera (Miller H. E. Moore, established in a place called "Lagoa Seca" (savanna-like stunted vegetation. The samples were herborized and included in the UFP Herbarium (Universidade Federal de Pernambuco, Recife, PE and the TEPB Herbarium (Universidade Federal do Piauí, Teresina, PI. In relation to the substrate, the "carnaubeira" showed a high incidence of Myxomycetes (70% on living stipitis and dead leaves. Sixteen species belonging to Ceratiomyxaceae (Ceratiomyxa lsp., Didymiaceae (Diachea lsp., Didymium 2spp., Physaraceae (Craterium lsp., Physarum 4spp., Trichiaceae (Arcyria 2spp. and Stemonitaceae (Comatricha 3spp

  18. Exploring intentions of physician-scientist trainees: factors influencing MD and MD/PhD interest in research careers.

    Science.gov (United States)

    Kwan, Jennifer M; Daye, Dania; Schmidt, Mary Lou; Conlon, Claudia Morrissey; Kim, Hajwa; Gaonkar, Bilwaj; Payne, Aimee S; Riddle, Megan; Madera, Sharline; Adami, Alexander J; Winter, Kate Quinn

    2017-07-11

    Prior studies have described the career paths of physician-scientist candidates after graduation, but the factors that influence career choices at the candidate stage remain unclear. Additionally, previous work has focused on MD/PhDs, despite many physician-scientists being MDs. This study sought to identify career sector intentions, important factors in career selection, and experienced and predicted obstacles to career success that influence the career choices of MD candidates, MD candidates with research-intense career intentions (MD-RI), and MD/PhD candidates. A 70-question survey was administered to students at 5 academic medical centers with Medical Scientist Training Programs (MSTPs) and Clinical and Translational Science Awards (CTSA) from the NIH. Data were analyzed using bivariate or multivariate analyses. More MD/PhD and MD-RI candidates anticipated or had experienced obstacles related to balancing academic and family responsibilities and to balancing clinical, research, and education responsibilities, whereas more MD candidates indicated experienced and predicted obstacles related to loan repayment. MD/PhD candidates expressed higher interest in basic and translational research compared to MD-RI candidates, who indicated more interest in clinical research. Overall, MD-RI candidates displayed a profile distinct from both MD/PhD and MD candidates. MD/PhD and MD-RI candidates experience obstacles that influence their intentions to pursue academic medical careers from the earliest training stage, obstacles which differ from those of their MD peers. The differences between the aspirations of and challenges facing MD, MD-RI and MD/PhD candidates present opportunities for training programs to target curricula and support services to ensure the career development of successful physician-scientists.

  19. Crocidura sicula Miller, 1900 (Mammalia, Soricidae: a possible new record from Comino island (Maltese Islands

    Directory of Open Access Journals (Sweden)

    Giovanni Amori

    2011-09-01

    Full Text Available The presence of Crocidura sicula Miller, 1900 is reported for the first time from the Comino island. Two specimenswere obtained from the analysis of Long-eared Owl Asio otus (Linnaeus, 1758 pellets.

  20. 76 FR 18151 - Kootenai National Forest, Lincoln County, MT; Miller West Fisher Project

    Science.gov (United States)

    2011-04-01

    ..., prescribed fire, watershed rehabilitation activities, pool creation in Miller Creek, improvement of trails..., increase big game security through reduction in open road density (ORD), and to create grizzly bear...

  1. [Determination of trace elements in Aloe barbadensis Miller irrigated with seawater by atomic absorption spectrophotometry].

    Science.gov (United States)

    Liu, Chun-Hui; Wang, Chang-Hai; Liu, Zhao-Pu

    2008-03-01

    The dry leaves of Aloe barbadensis Miller irrigated with seawater were dissolved in nitric acid and then oxygenated by perchloric acid. Nine kinds of trace elements in the samples were determined by atomic absorption spectrophotometry, including calcium, potassium, magnesium, sodium, manganese, zinc, iron, copper and lead, with added lanthanum chloride as releaser to eliminate the interference of co-existent ions. The recoveries were 96.58%-104.31%, and the relative standard deviations of sample determination (10 times) were less than 2%. This method is simple, sensitive and rapid with satisfactory results and good reproducibility. The results indicated that there were rich Ca, Mg, K and Na, and moderate Mn, Zn and Fe elements in the Aloe barbadensis Miller irrigated with seawater. However, the concentrations of Cu and Pb were low. Therefore, Aloe barbadensis Miller irrigated with seawater has officinal and economic values. These results provide data for further research on Aloe barbadensis Miller irrigated with seawater.

  2. Performance analysis and optimization of a supercharged Miller cycle Otto engine

    Energy Technology Data Exchange (ETDEWEB)

    Chih Wu; Puzinauskas, P.V. [US Naval Academy, Annapolis, MD (United States). Dept. of Mechanical Engineering; Tsai, J.S. [Yung Ta Institute of Technology and Commerce, Ping Tung (China). Dept. of Mechanical Engineering

    2003-04-01

    One of the major alternatives of the Otto cycle has been examined to determine its potential for increased efficiency and net work power in the spark ignited internal combustion engine is to shorten the compression process relative to the expansion process by early close or late of intake valve. The modified Otto cycle is called Miller cycle. This paper deals with the analysis of a supercharged Otto engine adopted for Miller cycle operation. The Miller cycle shows no efficiency advantage and suffers a penalty in power output in the normally aspirated version. In the supercharged Otto engine adopted for Miller cycle version, it has no efficiency advantage but does provide increased net work output with reduced propensity to engine knock problem. Sensitivity analysis of cycle efficiency versus early close of intake valve and that of cycle net work versus early close of intake valve are performed. Optimization on the cycle efficiency is obtained. (author)

  3. Obituary: Timothy P. McCullough, Jr., 1910-2004

    Science.gov (United States)

    McCullough, Charles

    2007-12-01

    Timothy Pendleton McCullough Jr., 93, a retired research physicist who was a pioneer in the measurement of microwave radiation from planetary surfaces, died of cardiac arrest on 19 November 2004, at Inova Fairfax Hospital. He lived in Springfield, VA. McCullough, who was principally a radio astronomer, published 22 scientific research papers while working in the Atmosphere and Astrophysics Division of NRL, from 1946 until his retirement in 1975. He spent the early part of his career in planetary observation and was among the first in his field to use radio astronomy to measure the surface temperature of Venus. He also studied Mars and Jupiter. Later, his interest turned to supernovas, galaxies and solar flares. He was an emeritus member of the American Astronomical Society and a member of the Sigma Xi Scientific Research Society. McCullough was born on 9 December 1910 in Vardaman, Mississippi. His father, Timothy P. McCullough, was a farmer and bookkeeper. His mother, Annie W. McCullough, was a homemaker. Timothy McCullough, Jr.'s parents, as well as two sisters and a brother, are deceased. McCullough graduated from the University of Mississippi in Oxford in 1936 and received a master's degree in physics from North Carolina State University in Raleigh. He taught physics and aviation navigation before entering the Navy during World War II. He instructed Russian sailors on anti-submarine warfare. McCullough left the Navy at the end of the war, but continued to serve in the Naval Reserve. He was recalled to active duty during the Korean War and was stationed at Potomac River Naval Command, where he wrote technical documents on electronic warfare systems. McCullough retired from the Naval Reserve in 1969 with the rank of commander. He was a charter member of First Baptist Church in Springfield and a former deacon and Sunday school teacher at First Baptist Church in Alexandria. Survivors include his wife of 63 years, Virginia Ball McCullough of Springfield; three

  4. On possibilities of application of Miller formula for determination of parameters of Micropixel Avalanche Photodiodes

    CERN Document Server

    Sadygov, Z; Akhmedov, G; Akhmedov, F; Mukhtarov, R; Sadygov, A; Titov, A; Zhezher, V

    2014-01-01

    Miller formula modified to take into account voltage drop on serial resistor of an avalanche photodiode is considered. It is proven by experimental data that modified Miller formula can describe operation of both regular and micropixel avalanche photodiodes with good enough precision. It is shown that operation parameters of the devices can be determined using a linear extrapolation of the voltage-current curve for both regular avalanche photodiode and the one operating in Geiger mode.

  5. On possibilities of application of Miller formula for determination of parameters of Micropixel Avalanche Photodiodes

    OpenAIRE

    Sadygov, Z.; Abdullaev, Kh.; Akhmedov, G.; Akhmedov, F.; Mukhtarov, R.; Sadygov, A.; Titov, A.; Zhezher, V.

    2014-01-01

    Miller formula modified to take into account voltage drop on serial resistor of an avalanche photodiode is considered. It is proven by experimental data that modified Miller formula can describe operation of both regular and micropixel avalanche photodiodes with good enough precision. It is shown that operation parameters of the devices can be determined using a linear extrapolation of the voltage-current curve for both regular avalanche photodiode and the one operating in Geiger mode.

  6. Primordial soup was edible: abiotically produced Miller-Urey mixture supports bacterial growth

    OpenAIRE

    Xueshu Xie; Daniel Backman; Albert T. Lebedev; Viatcheslav B. Artaev; Liying Jiang; Leopold L. Ilag; Zubarev, Roman A.

    2015-01-01

    Sixty years after the seminal Miller-Urey experiment that abiotically produced a mixture of racemized amino acids, we provide a definite proof that this primordial soup, when properly cooked, was edible for primitive organisms. Direct admixture of even small amounts of Miller-Urey mixture strongly inhibits E. coli bacteria growth due to the toxicity of abundant components, such as cyanides. However, these toxic compounds are both volatile and extremely reactive, while bacteria are highly capa...

  7. Combination of Cerebral Demyelination and Graves Disease in a Case with Miller Fisher Syndrome

    OpenAIRE

    Sibel Güler; Levent Sinan Bir

    2010-01-01

    A 44-year-old male patient with a diagnosis of Miller Fisher syndrome, Graves disease and central nervous system demyelination is presented. Clinical and laboratory findings supported the diagnosis of Miller Fisher syndrome. On T2-weighted sections of cranial magnetic resonance imaging, many ovoid-shaped, hyperintense lesions in bilateral deep white matter were detected. Magnetic resonance imaging spectroscopy demonstrated low N-acetylaspartate to creatine (NAA/Cr) ratio consistent with demye...

  8. Batch By Batch Longitudinal Emittance Blowup MD

    CERN Document Server

    Mastoridis, T; Butterworth, A; Jaussi, M; Molendijk, J

    2012-01-01

    The transverse bunch emittance increases significantly at 450 GeV from the time of injection till the ramp due to IBS. By selectively blowing up the longitudinal emittance of the incoming batch at each injection, it should be possible to reduce the transverse emittance growth rates due to IBS. An MD was conducted on April 22nd 2012 to test the feasibility and performance of the batch-by-batch longitudinal emittance blowup. There were three main goals during the MD. First, to test the developed hardware, firmware, and software for the batch-by-batch blowup. Then, to measure the transverse emittance growth rates of blown-up and "witness" batches to quantify any improvement, and finally to test the ALLInjectSequencer class, which deals with the complicated gymnastics of introducing or masking the new batch to various RF loops.

  9. Direct NOE simulation from long MD trajectories

    Science.gov (United States)

    Chalmers, G.; Glushka, J. N.; Foley, B. L.; Woods, R. J.; Prestegard, J. H.

    2016-04-01

    A software package, MD2NOE, is presented which calculates Nuclear Overhauser Effect (NOE) build-up curves directly from molecular dynamics (MD) trajectories. It differs from traditional approaches in that it calculates correlation functions directly from the trajectory instead of extracting inverse sixth power distance terms as an intermediate step in calculating NOEs. This is particularly important for molecules that sample conformational states on a timescale similar to molecular reorientation. The package is tested on sucrose and results are shown to differ in small but significant ways from those calculated using an inverse sixth power assumption. Results are also compared to experiment and found to be in reasonable agreement despite an expected underestimation of water viscosity by the water model selected.

  10. MD on UFOs at MKIs and MKQs

    CERN Document Server

    Baer, T; Bartmann, W; Bracco, C; Carlier, E; Dehning, B; Garrel, N; Goddard, B; Jackson, S; Jimenez, M; Kain, V; Mertens, V; Misiowiec, M; Nordt, A; Papotti, G; Uythoven, J; Wenninger, J; Zerlauth, M; Zamantzas, C; Zimmermann, F

    2012-01-01

    UFOs ("Unidentified Falling Objects") are expected to be one of the major known performance limitation of the LHC. In this MD, the production mechanism and the dynamics of UFOs at the injection kicker magnets (MKIs) and the tune kicker magnets (MKQs) were studied. This was done by pulsing the MKIs and MKQs on a gap in the partly filled machine. During the MD, in total 58 UFO-type beam loss patterns were observed directly after pulsing the MKIs. None were observed after pulsing the MKQs, which provides important input for possible mitigation strategies. The temporal and spatial distribution of the UFO events could be determined by using a dedicated BLM Study Buffer, the implications for the UFO dynamics are discussed.

  11. MD5的Keygenme分析

    Institute of Scientific and Technical Information of China (English)

    Firebig

    2006-01-01

    闲来无事,抓出个不知何时下的Keygenme练练手,分析后可知.这个Keygenme有2张数据表,由注册名经MD5运算后进行查表,得出2个DWORD数据.然后再由注册码经过一个可逆循环得出2个DWORD数据.最后对比是否正确。(MD5的具体介绍黑防6期有说明)

  12. Classical MD calculations with parallel computers

    Energy Technology Data Exchange (ETDEWEB)

    Matsumoto, Mitsuhiro [Nagoya Univ. (Japan)

    1998-03-01

    We have developed parallel computation codes for a classical molecular dynamics (MD) method. In order to use them on work station clusters as well as parallel super computers, we use MPI (message passing interface) library for distributed-memory type computers. Two algorithms are compared: (1) particle parallelism technique: easy to install, effective for rather small number of processors. (2) region parallelism technique: take some time to install, effective even for many nodes. (J.P.N.)

  13. The renaissance man of burn surgery: Basil A. Pruitt Jr.

    Science.gov (United States)

    Capek, Karel D; Foncerrada, Guillermo; Clayton, R Patrick; Sljivich, Michaela; Voigt, Charles D; Hundeshagen, Gabriel; Cambiaso-Daniel, Janos; Porter, Craig; Guillory, Ashley; Herndon, David N

    2017-07-08

    Dr. Basil A. Pruitt Jr., a consummate clinical and translational surgeon-scientist, has been spent over half a century at the forefront of an advancing standard of burn care. Commanding the US Army Institute for Surgical Research in San Antonio, he trained generations of leading burn clinicians and allied scientists. At his direction, there were forged discoveries in resuscitation from shock, treatment of inhalation injury, control of burn-related infections, prevention of iatrogenic complications, and understanding the sympathetic, endocrine, and immune responses to burn injury. Most consequentially, this team was among the first recognize and define alterations in the basal metabolic rate and thermoregulation consequent to burn injury. These investigations prompted groundbreaking insights into the coordinated nervous, autonomic, endocrine, immune, and metabolic outflows that a severely-burned patient uses to remain alive and restore homeostasis. Marking his scientific consequence, many of his reports continue bear fruit when viewed through a contemporary lens. This paper summarizes some of the major findings of his career thus far, and is intended to complement a Festschrift recently held in his honor. Not applicable.

  14. East Weddell Sea echinoids from the JR275 expedition

    Directory of Open Access Journals (Sweden)

    Thomas Saucède

    2015-05-01

    Full Text Available Information regarding the echinoids in this dataset is based on the Agassiz Trawl (AGT and epibenthic sledge (EBS samples collected during the British Antarctic Survey cruise JR275 on the RRS James Clark Ross in the austral summer 2012. A total of 56 (1 at the South Orkneys and 55 in the Eastern Weddell Sea Agassiz Trawl and 18 (2 at the South Orkneys and 16 in the Eastern Weddell Sea epibenthic sledge deployments were performed at depths ranging from ~280 to ~2060 m. This presents a unique collection for the Antarctic benthic biodiversity assessment of an important group of benthic invertebrates. In total 487 specimens belonging to six families, 15 genera, and 22 morphospecies were collected. The species richness per station varied between one and six. Total species richness represents 27% of the 82 echinoid species ever recorded in the Southern Ocean (David et al. 2005b, Pierrat et al. 2012, Saucède et al. 2014. The Cidaridae (sub-family Ctenocidarinae and Schizasteridae are the two most speciose families in the dataset. They comprise seven and nine species respectively. This is illustrative of the overall pattern of echinoid diversity in the Southern Ocean where 65% of Antarctic species belong to the families Schizasteridae and Cidaridae (Pierrat et al. 2012.

  15. 2015 AMCA Memorial Lecture Honoree: Dr. Richard Floyd Darsie, Jr.

    Science.gov (United States)

    Day, Jonathan F

    2015-12-01

    Richard Floyd Darsie, Jr. (1915-2014) is the 2015 American Mosquito Control Association Memorial Lecture Honoree. He was one of the greatest mosquito taxonomists of the 20th century and died peacefully on April 10, 2014, in Grove City, PA, at the age of 99 after a professional career that spanned eight decades. Dick's broad areas of interest and training made him a versatile scientist, teacher, and researcher. His intense interest in adult and immature mosquito morphology and taxonomy, as well as mosquito distribution and bionomics, started early in his career at two early academic postings: Franklin and Marshall College (1949-54) and the University of Delaware (1954-62). Dick would take his mosquito interests with him to postings and research projects around the world: Nepal, the Philippines, Atlanta, El Salvador, Guatemala, Fort Collins, South Carolina, Argentina, and Florida. His travels and studies would make him an international expert on mosquito taxonomy. Dick's legacy lives on in the hundreds of students from across the globe who learned mosquito identification skills from this world-renowned mosquito taxonomist. All will proudly profess that, "I learned mosquito identification from Dr. Darsie." And that is all that is needed to prove one's credentials in the field, learning the art from the best there is.

  16. Cerebellar and pontine tegmental hypermetabolism in miller-fisher syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yu Kyrong; Kim, Ji Soo; Lee, Won Woo; Kim, Sang Eun [Seoul National Univ. College of Medicine, Seoul (Korea, Republic of)

    2007-07-01

    Miller Fisher syndrome (MFS) has been considered as a variant of Guillain-Barre syndrome (GBS), a type of acute immune neuropathies involving peripheral nerve system. Unlike GBS, presence of cerebellar type ataxia and supranuclear ophthalmioplesia in MFS suggests additional involvement of the central nervous system. To determine involvement of the central nervous system in MFS, we investigated the cerebral metabolic abnormalities in patients with MFS using FDG PET. Nine patients who were diagnosed as MFS based on acute ophthalmoplegia, ataxia, and areflexia without other identifiable causes participated in this study. In six patients, serum antibodies possibly related with symptom of MFS (anti- GQ1b or anti-GM1) were detected at the time of the study. With the interval of 25 26 days (range: 3-83 days) from the symptom on set, brain FDG PET were underwent in patients and compared with those from healthy controls. In group analysis comparing with healthy controls, FDG PET of patients revealed increased metabolism in the bilateral cerebellar hemispheres and vermis, and the thalamus. In contrast, the occipital cortex showed decreased metabolism. Individual analyses disclosed hypermetabolism in the cerebellar vermis or hemispheres in 5, and in the pontine tegmentum in 2 of the 9 patients. We also found that the cerebellar vermian hypermetabolism was inversely correlated with the interval between from the symptom on set to PET study. Moreover, follow-up PET of a patient demonstrated that cerebellar hypermetabolism decreased markedly with an improvement of the ophthalmoplegia and ataxia. These findings indicate an involvement of the central nervous system in MFS and suggest an antibody-associated acute inflammatory process as a mechanism of this disorder.

  17. 78 FR 25942 - J.R. Simplot Co.; Availability of Petition for Determination of Nonregulated Status of Potato...

    Science.gov (United States)

    2013-05-03

    ... Animal and Plant Health Inspection Service J.R. Simplot Co.; Availability of Petition for Determination... petition from the J.R. Simplot Company (Simplot) seeking a determination of nonregulated status of potatoes... Petition Number 13-022-01p) from the J.R. Simplot Company (Simplot) of Boise, ID, seeking a...

  18. Lonnie R. Snowden Jr.: Award for Distinguished Contributions to Research in Public Policy.

    Science.gov (United States)

    2014-11-01

    The Award for Distinguished Contributions to Research in Public Policy is given to a psychologist who has made a distinguished empirical and/or theoretical contribution to research in public policy, either through a single extraordinary achievement or a lifetime of work. The 2014 recipient of this award is Lonnie R. Snowden Jr. "Over the past several decades, Lonnie R. Snowden Jr. has systematically built a research agenda on the financing and organization of mental health services that has driven much of our current health policy reform efforts." Snowden Jr.'s award citation, biography, and a selected bibliography are presented here. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  19. Assessment of J-R Curves Obtained from Precracked Charpy Samples

    Science.gov (United States)

    1985-09-01

    16 3. J-R curves for A723, Class 1, Grade 4 pressure vessel steel . 17 4. J-R curves for HY80 steel . 18 5. J-R curves for HY130 steel . 19 DTIC t,. 1 NV...In HY80 and KY130 steels , it is clear that significant strain-hardening occurred. The effect of strain-hardening could be crack growth at peak load...aimmoSO ff nwoa MW Identify b black nrnmsbm’) 3-R curves were determined for five materials (7075-T651; 2024-T351; HY13O; HY80 ; and A723, Class 1

  20. William D. Harper, Jr, MS, DC: anything can cause anything.

    Science.gov (United States)

    Keating, Joseph C

    2008-03-01

    Trained as an engineer and a chiropractor, William D. Harper, Jr. made his career in the healing arts as instructor, writer and president of the Texas Chiropractic College (TCC). A native of Texas who grew up in various locales in the Lone Star State, in Mexico and in the Boston area, he took his bachelor's and master's degree in engineering in 1933 and 1934 from the Massachusetts Institute of Technology, and his chiropractic degree at TCC in 1942. Dissatisfied with the "foot-on-the-hose" concept of subluxation syndrome (D.D. Palmer's second theory), Dr. Harper studied and wrote about aberrant neural irritation as an alternative explanation for disease and for the broad clinical value he perceived in the chiropractic art. In this he paralleled much of D.D. Palmer's third theory of chiropractic. His often reprinted textbook, Anything Can Cause Anything, brought together much of what he had lectured and written about in numerous published articles. He was well prepared for the defense of chiropractic that he offered in 1965 in the trial of the England case in federal district court in Louisiana. The case was lost when the court ruled that the legislature rather than the judiciary should decide whether to permit chiropractors to practice, but Harper's performance was considered excellent. He went on to guide the TCC as president from 1965 through 1976, its first 11 years after relocating from San Antonio to Pasadena, Texas. Harper built the school - its faculty, staff and facilities - from very meager beginnings to a small but financially viable institution when he departed. Along the way he found fault with both chiropractic political camps that vied for federal recognition as the accrediting agency for chiropractic colleges in the United States. Dr. Bill Harper was a maverick determined to do things his way, and in many respects he was successful. He left a mark on the profession that merits critical analysis.

  1. Lynn White Jr. and the greening-of-religion hypothesis.

    Science.gov (United States)

    Taylor, Bron; Van Wieren, Gretel; Zaleha, Bernard Daley

    2016-10-01

    Lynn White Jr.'s "The Historical Roots of Our Ecologic Crisis," which was published in Science in 1967, has played a critical role in precipitating interdisciplinary environmental studies. Although White advances a multifaceted argument, most respondents focus on his claim that the Judeo-Christian tradition, especially Christianity, has promoted anthropocentric attitudes and environmentally destructive behaviors. Decades later, some scholars argue contrarily that Christianity in particular and the world's predominant religions in general are becoming more environmentally friendly, known as the greening-of-religion hypothesis. To test these claims, we conducted a comprehensive review of over 700 articles-historical, qualitative, and quantitative-that are pertinent to them. Although definitive conclusions are difficult, we identified many themes and dynamics that hinder environmental understanding and mobilization, including conservative theological orientations and beliefs about the role of divine agency in preventing or promoting natural events, whether the religion is an Abrahamic tradition or originated in Asia. On balance, we found the thrust of White's thesis is supported, whereas the greening-of-religion hypothesis is not. We also found that indigenous traditions often foster proenvironmental perceptions. This finding suggests that indigenous traditions may be more likely to be proenvironmental than other religious systems and that some nature-based cosmologies and value systems function similarly. Although we conclude White's thesis and subsequent claims are largely born out, additional research is needed to better understand under what circumstances and communication strategies religious or other individuals and groups may be more effectively mobilized to respond to contemporary environmental challenges. © 2016 Society for Conservation Biology.

  2. Obituary: Raymond Edwin White Jr., 1933-2004

    Science.gov (United States)

    Liebert, James William

    2004-12-01

    Raymond E. White, Jr., died unexpectedly at his home, in the early morning hours of October 12, 2004. Death appears to have been caused by severe diabetic shock. He retired from the Department of Astronomy/Steward Observatory in July 1999 with the title of University Distinguished Professor, after serving on the faculty of this institution for over 35 years. He was born in Freeport, Illinois, on 6 May 1933, to Beatrice and Raymond E, Sr. -the latter being a career soldier in the US Army. Ray's early schooling took place in Illinois, New Jersey, Germany and Switzerland, following his father's assignments. He obtained a bachelors degree from the University of Illinois in 1955. Next Ray enlisted in the US Army, but quickly was enrolled in Officer Candidate School. He then served as lst Lt. in the US Army Corps of Engineers. Although military affairs remained a lifelong interest, and he was a member of the Company of Military Historians, Ray decided after three years to return to academia. He entered the astronomy PhD program at the University of Illinois in 1958. His PhD dissertation was supervised by Ivan R. King. Ray accepted a faculty position at the University of Arizona in 1964. First and foremost, Ray White was known at Arizona as an excellent teacher, revered by a large number of former students. When the astronomy major program was begun in 1967, Ray was one of three, original, major advisors. Over the next three decades, he was a leader at the University level in reforming the undergraduate program and courses. He was selected Outstanding University Faculty Member in April 1989 and he served as one of a handful of professors who are Faculty Fellows. These Fellows devote untold hundreds of hours as part-time residents at student dormitories, to give students a friendly face to address their problems. In 1995, Ray was among the first group of faculty to be recognized as University Distinguished Professors. In the year of his retirement, 1999, University

  3. Obituary: Edward W. Burke, Jr. (1924-2011)

    Science.gov (United States)

    Bloomer, Raymond, Jr.

    2011-12-01

    Dr. Edward W. Burke Jr. passed away on June 15, 2011, after suffering a heart attack. Dr. Burke devoted his professional life to the research and teaching of physics and astronomy at King College in Bristol, Tennessee. Edward W. Burke, Jr., was born in Macon, Georgia, on September 16, 1924. He was a Navy veteran, having been commissioned as an ensign in 1944. He served in the Pacific near the end of World War II. He proceeded to complete his undergraduate degree in mathematics from Presbyterian College in 1947 and pursued the M.S. and Ph.D. in physics (1949 and 1954, respectively) at the University of Wisconsin. Under the direction of Professor Julian Mack, his thesis was titled "Isotope Shift in the Spectra of Boron." Although he did research in atomic spectra in the early part of his career, his interest in astronomy and variable stars in particular were his primary interests during his long academic career. Dr. Burke began his illustrious career at King College in 1949. He initiated the astronomy program there in 1950, included constructing a 12.5 inch Newtonian telescope, homemade as was most everything in those days. Many of his students learned about photometry at the Burke Observatory on the college campus. Burke was known for his trips to the Kitt Peak and Lowell observatories accompanied by undergraduate students on his trips, all of which were made by automobile which he preferred over flying. His initial interest in Ap stars later broadened into variable and especially eclipsing binary stars. His motivation was maintained by his desire to have his students experience basic research and to spark their interest in advanced degrees. Numerous students achieved advanced science and medical degrees because of Burke's encouragement and mentoring. In 1959, Dr. Burke was awarded a Fulbright professorship and traveled to Chile where he taught physics for a year in the Engineering School at the University of Chile in Santiago. He worked to establish a physics

  4. Integrative Medicine Program- MD Anderson Cancer Center

    Directory of Open Access Journals (Sweden)

    Richard T Lee

    2012-06-01

    Full Text Available The Integrative Medicine Program at MD Anderson Cancer Center was first established in 1998.  Our mission is to empower patients with cancer and their families to become active partners in their own physical, psycho-spiritual, and social health through personalized education and evidenced-based clinical care to optimize health, quality of life, and clinical outcomes across the cancer continuum.  The program consists of three main components: clinical care, research, and education.  The Integrative Medicine Center provides clinical services to patients through individual and group programs.  The clinical philosophy of the center is to work collaboratively with the oncology teams to build comprehensive and integrative care plans that are personalized, evidence-based, and safe with the goal of improving clinical outcomes.  The individual services comprise of integrative oncology consultation, acupuncture, meditation, music therapy, nutrition, and oncology massage.  The center also provides a variety of group programs including meditation, yoga, tai chi, cooking classes and others.  Over the past 13 years, over 70,000 patients and families have participated in services and programs offered by the center.  The research portfolio focuses on three main areas: mind-body interventions, acupuncture, and meditation.  This lecture will focus on providing an overview of the Integrative Medicine Program at MD Anderson with a focus on the clinical services provided.  Participants will learn about the integrative clinical model and how this is applied to the care of cancer patients at MD Anderson Cancer Center.  Current and future research topics will be discussed as well as patient cases.

  5. Dawbeney Turbervile, MD (1612-1696).

    Science.gov (United States)

    Simunovic, Matthew P

    2012-03-01

    The year 2012 marks the quatercentenary of the birth of Dawbeney Turbervile,MD(1612-1696), one-time Royalist soldier and later ophthalmologist to England’s Princess Anne, the diarist Samuel Pepys, the natural philosopher Robert Boyle, and the astronomer Walter Pope. Turbervile is remarkable for many reasons: He specialized at a time when generalization was prized; though he was a qualified physician, he also practiced the trade of surgery. Furthermore, he provided in his communications with the Royal Society early descriptions of achromatopsia, ocular foreign body removal with a magnet, and tic doloreaux. He is a forebear worth remembering

  6. MD Test of a Ballistic Optics

    CERN Document Server

    Garcia-Tabares Valdivieso, Ana; Salvachua Ferrando, Belen Maria; Skowronski, Piotr Krzysztof; Solfaroli Camillocci, Matteo; Tomas Garcia, Rogelio; Wenninger, Jorg; Coello De Portugal - Martinez Vazquez, Jaime Maria; CERN. Geneva. ATS Department

    2016-01-01

    The ballistic optics is designed to improve the understanding of optical errors and BPM systematic effects in the critical triplet region. The particularity of that optics is that the triplet is switched off, effectively transforming the triplets on both sides of IR1 and IR5 into drift spaces. Advantage can be taken from that fact to localize better errors in the Q4-Q5-triplet region. During this MD this new optics was tested for the first time at injection with beam 2.

  7. Orlando C. Kirton, MD, FACS, FCCM, FCCP.

    Science.gov (United States)

    Pyrtek, Ludwig J

    2007-12-01

    The chair is named for Ludwig J. Pyrtek, MD, an esteemed surgeon at Hartford Hospital, who was devoted to the care of his patients and was an outstanding educator within his chosen field. A unique aspect of the chair is that its income is not used to support the salary of the director but is used to enhance the education activities of the department, such as the purchasing of state-of-the-art teaching devices, support of surgical resident research activities, educational travel for residents and honoraria for nationally/internationally known clinicians/scientists to speak at grand rounds.

  8. SITE TECHNOLOGY CAPSULE: J.R. SIMPLOT EX-SITU BIOREMEDIATION TECHNOLOGY: DINOSEB

    Science.gov (United States)

    The J.R. Simplot Ex-Situ Bioremediation Technology is designed to anaerobically degrade nitroaromatic and energetic compounds in soils and liquids without forming identifiable toxic intermediate compounds produced by other biotreatment methods. This technology was evaluated un...

  9. Week-long celebration of Dr. Martin Luther King Jr. legacy continues

    OpenAIRE

    Owczarski, Mark

    2006-01-01

    A wide range of educational and cultural programs and community service events are underway as Virginia Tech celebrates Dr. Martin Luther King Jr. Week Jan. 15-20. All events are free (unless otherwise noted) and open to the public.

  10. Leo Piilonen appointed William E. Hassinger, Jr. Senior Faculty Fellow in Physics

    OpenAIRE

    Owczarski, Mark

    2010-01-01

    Leo Piilonen, professor of physics in the College of Science at Virginia Tech, was recently appointed the William E. Hassinger, Jr., Senior Faculty Fellow in Physics by the Virginia Tech Board of Visitors.

  11. Maya Angelou to speak during Virginia Tech's third annual Martin Luther King Jr. celebration

    OpenAIRE

    Williams, Meghan

    2008-01-01

    A remarkable woman who is hailed as one of the greatest voices of contemporary literature, Maya Angelou, will be a guest speaker during the third annual Dr. Martin Luther King Jr. celebration at Virginia Tech.

  12. Maya Angelou to visit Virginia Tech during third annual Martin Luther King, Jr. celebration

    OpenAIRE

    Williams, Meghan

    2007-01-01

    A remarkable woman who is hailed as one of the greatest voices of contemporary literature, Maya Angelou, will be a guest speaker during the third annual Dr. Martin Luther King Jr. celebration at Virginia Tech.

  13. Miller's Pyramid and Core Competency Assessment: A Study in Relationship Construct Validity.

    Science.gov (United States)

    Williams, Betsy White; Byrne, Phil D; Welindt, Dillon; Williams, Michael V

    2016-01-01

    Continuous professional development relies on the link between performance and an educational process aimed at improving knowledge and skill. One of the most broadly used frameworks for assessing skills is Miller's Pyramid. This Pyramid has a series of levels of achievement beginning with knowledge (at the base) and ending with routine application in the clinical setting. The purpose of this study was to determine the degree of convergence of two measurement methods, one based on Miller's framework, the second using the Accreditation Council for Graduate Medical Education/American Board of Medical Specialties (ACGME/ABMS) Core Competency framework. The data were gathered from the faculty of a large, Midwestern regional health care provider and hospital system. Data from 264 respondents were studied. The 360° data were from raters of physicians holding supervisory roles in the organization. The scale items were taken from an instrument that has been validated for both structure and known group prediction. The Miller scale was purposely built for this application. The questions were designed to describe each level of the model. The Miller scale was reduced to a single dimension. This result was then regressed on the items from the 360° item ratings. Results of a multivariate analysis of variance isolated a significant relationship between the Miller's Pyramid score and the competency items (P core competencies. Equally important is the finding that while they are related they are not identical. These findings have implications for continuous professional development programing design.

  14. Backside wear of Miller-Galante I and Insall-Burstein II tibial inserts.

    Science.gov (United States)

    Taki, Naoya; Goldberg, Victor M; Kraay, Matthew J; Rimnac, Clare M

    2004-11-01

    The objective of this study was to determine if there was a difference in the amount, type, and location of backside wear in the Miller-Galante I and Insall-Burstein II PE tibial inserts. A secondary objective was to determine if backside wear damage in these two designs was a function of clinical factors (patient height, weight, gender, age, and length of time of implantation), shelf life of the PE tibial insert, and tibial component thickness. Backside wear damage was assessed on 24 Miller-Galante I and 11 Insall-Burstein II tibial inserts (implantation time, 0.5-12.4 years). For both groups combined, implantation time was positively correlated to wear damage and to PE peg height into screw holes. The Miller-Galante I group had significantly larger PE pegs than the Insall-Burstein II group. The Miller-Galante I group had significantly more burnishing and larger PE pegs posteriorly than anteriorly. There was no correlation between insert shelf life before initial surgery and backside wear. The thinner the component, the larger the total damage scores in the Miller-Galante I group. This study supports the hypothesis that backside wear of PE tibial inserts may be influenced by design and component thickness and by clinical factors.

  15. ProtoMD: A prototyping toolkit for multiscale molecular dynamics

    Science.gov (United States)

    Somogyi, Endre; Mansour, Andrew Abi; Ortoleva, Peter J.

    2016-05-01

    ProtoMD is a toolkit that facilitates the development of algorithms for multiscale molecular dynamics (MD) simulations. It is designed for multiscale methods which capture the dynamic transfer of information across multiple spatial scales, such as the atomic to the mesoscopic scale, via coevolving microscopic and coarse-grained (CG) variables. ProtoMD can be also be used to calibrate parameters needed in traditional CG-MD methods. The toolkit integrates 'GROMACS wrapper' to initiate MD simulations, and 'MDAnalysis' to analyze and manipulate trajectory files. It facilitates experimentation with a spectrum of coarse-grained variables, prototyping rare events (such as chemical reactions), or simulating nanocharacterization experiments such as terahertz spectroscopy, AFM, nanopore, and time-of-flight mass spectroscopy. ProtoMD is written in python and is freely available under the GNU General Public License from github.com/CTCNano/proto_md.

  16. Case report: massive postpartum transfusion of Jr(a+) red cells in the presence of anti-Jra.

    Science.gov (United States)

    Yuan, S; Armour, R; Reid, A; Abdel-Rahman, K F; Rumsey, D M; Phillips, M; Nester, T

    2005-01-01

    Jr(a) is a high-prevalence antigen. The rare Jr(a-) individuals can form anti-Jr(a) after exposure to the Jr(a) antigen through transfusion or pregnancy. The clinical significance of anti-Jr(a) is not well established. This study reports a case of a 31-year-old woman with a previously identified anti-Jr(a) who required massive transfusion of RBCs after developing life-threatening postpartum disseminated intravascular coagulopathy. Despite the emergent transfusion of 15 units of Jr(a) untested RBCs, she did not develop laboratory or clinical evidence of acute hemolysis. The patient's anti-Jr(a) had a pretransfusion titer of 4 and a monocyte monolayer assay (MMA) reactivity of 68.5% (reactivity > 5% is considered capable of shortening the survival of incompatible RBCs). The titer increased fourfold to 64 and the MMA reactivity was 72.5% on Day 10 posttransfusion. Review of laboratory data showed evidence of a mild delayed hemolytic transfusion reaction by Day 10 posttransfusion. Despite rare reports of hemolytic transfusion reactions due to anti-Jr(a) in the literature, most cases, including this one, report that this antibody is clinically insignificant or causes only mild delayed hemolysis. Clinicians should be advised to balance the risks of withholding transfusion with the small chance of significant hemolysis after transfusion of Jr(a+) RBCs in the presence of anti-Jr(a).

  17. Magnetoplasmadynamcis - Portrait of Macon C. 'Mike' Ellis, Jr

    Science.gov (United States)

    1962-01-01

    Portrait of Macon C. 'Mike' Ellis, Jr. James Hansen described Mike Ellis as 'the first and only person to be in charge of Langley's Magnetoplasmadynamcis (MPD) Branch.' He was 'an NACA veteran who was 42 years old when the branch was organized. Ellis had come to work at Langley in 1939, and over the course of his career at the laboratory, he had been involved in pioneering work on the aerodynamics of jet engines, ramjets, and supersonic inlets and nozzles. Fittingly, Ellis had worked for Eastman Jacobs and with Arthur Kantrowitz in the early 1940s, and he had heard firsthand accounts of his former colleagues' attempts to design a fusion reactor in the spring of 1938. By the late 1950s, Ellis was one of Langley's most outspoken believers in MPD's promise of technological benefits. Ellis encouraged Floyd Thompson's enthusiasm for MPD and persuaded Langley's senior staff of mostly engineers that MPD was a field of research vital to the future of NASA. When the time came to pick someone to head the new branch, Ellis was unquestionably the person for the job. 'Ellis was no extraordinary 'scientific brain.' As an aeronautical engineer, his talents were quite respectable, but he possessed no special competency in the physics of fluids beyond his experience in aerodynamics or gas dynamics. He was always the first to admit that the complexities of plasma physics and MPD were such that 'there was no way' that he personally could conduct basic MPD research. That challenge he would leave to minds more suited for it. But Ellis could bring the MPD researchers together as a unit, serve as their strong external advocate, shield them from front-office pressures, and make sure that they received the support they needed to carry out their work. 'I just tried to keep my head above water,' Ellis explains, 'and keep these *mad scientists' from going off on too many tangents, or going mad myself.' Published in James R. Hansen, Spaceflight Revolution: NASA Langley Research Center From

  18. Primordial soup was edible: abiotically produced Miller-Urey mixture supports bacterial growth.

    Science.gov (United States)

    Xie, Xueshu; Backman, Daniel; Lebedev, Albert T; Artaev, Viatcheslav B; Jiang, Liying; Ilag, Leopold L; Zubarev, Roman A

    2015-09-28

    Sixty years after the seminal Miller-Urey experiment that abiotically produced a mixture of racemized amino acids, we provide a definite proof that this primordial soup, when properly cooked, was edible for primitive organisms. Direct admixture of even small amounts of Miller-Urey mixture strongly inhibits E. coli bacteria growth due to the toxicity of abundant components, such as cyanides. However, these toxic compounds are both volatile and extremely reactive, while bacteria are highly capable of adaptation. Consequently, after bacterial adaptation to a mixture of the two most abundant abiotic amino acids, glycine and racemized alanine, dried and reconstituted MU soup was found to support bacterial growth and even accelerate it compared to a simple mixture of the two amino acids. Therefore, primordial Miller-Urey soup was perfectly suitable as a growth media for early life forms.

  19. Obituary: Ernest Hurst Cherrington, Jr., 1909-1996

    Science.gov (United States)

    Osterbrock, Donald E.

    2003-12-01

    Ernest H. Cherrington, Jr., a long-time member of the AAS, died in San Jose, California on 13 July 1996, following a long illness. He had a short but active career as a research astronomer at Perkins Observatory at Ohio Wesleyan University in Delaware, Ohio before World War II, in which he served as an officer in the Army Air Force. After the war ended he turned to full-time teaching and administration at the University of Akron, and then at Hood College in Frederick, Maryland. Ernest was born on 10 September 1909 in Westerville, Ohio, where his father, Ernest H. Cherrington, Sr., was a leader in the temperance movement and publisher of "American Issue", a Prohibitionist magazine. Ernest Jr.'s mother, Betty Clifford (née Denny) Cherrington, was a homemaker. He was an outstanding student in high school and at Ohio Wesleyan University, which he entered in 1927. The little university's Perkins Observatory with its 69-inch reflector, briefly the second largest telescope in the United States, had just been built and gone into operation. After graduating with a BA magna cum laude in astronomy in 1931, Ernest stayed on one more year and earned his MS with a thesis on the motion of material in the tail of Comet Morehouse, supervised by Nicholas T. Bobrovnikoff. In 1932 Ernest entered the University of California at Berkeley as a graduate student, with a one-year teaching assistantship in the Astronomical Department. This was followed by a two-year Lick Observatory Fellowship. In June 1933 he married Ann McAfee Naylor, who had been a classmate at Delaware High School and Ohio Wesleyan. Ernest did his PhD thesis on spectrophotometry of the Mg I b lines in the solar spectrum, using a high-resolution grating spectrograph on the Berkeley campus, designed by C. Donald Shane, his adviser. In this thesis, Ernest tested and improved the then current theory of strong absorption lines in stellar atmospheres. He also spent several short periods at Lick Observatory on Mount Hamilton

  20. New insights into prebiotic chemistry from Stanley Miller's spark discharge experiments.

    Science.gov (United States)

    Bada, Jeffrey L

    2013-03-07

    1953 was a banner year for biological chemistry: The double helix structure of DNA was published by Watson and Crick, Sanger's group announced the first amino acid sequence of a protein (insulin) and the synthesis of key biomolecules using simulated primordial Earth conditions has demonstrated by Miller. Miller's studies in particular transformed the study of the origin of life into a respectable field of inquiry and established the basis of prebiotic chemistry, a field of research that investigates how the components of life as we know it can be formed in a variety of cosmogeochemical environments. In this review, I cover the continued advances in prebiotic syntheses that Miller's pioneering work has inspired. The main focus is on recent state-of-the-art analyses carried out on archived samples of Miller's original experiments, some of which had never before been analyzed, discovered in his laboratory material just before his death in May 2007. One experiment utilized a reducing gas mixture and an apparatus configuration (referred to here as the "volcanic" apparatus) that could represent a water-rich volcanic eruption accompanied by lightning. Another included H(2)S as a component of the reducing gas mixture. Compared to the limited number of amino acids Miller identified, these new analyses have found that over 40 different amino acids and amines were synthesized, demonstrating the potential robust formation of important biologic compounds under possible cosmogeochemical conditions. These experiments are suggested to simulate long-lived volcanic island arc systems, an environment that could have provided a stable environment for some of the processes thought to be involved in chemical evolution and the origin of life. Some of the alternatives to the Miller-based prebiotic synthesis and the "primordial soup" paradigm are evaluated in the context of their relevance under plausible planetary conditions.

  1. Recurrent miller fisher syndrome with abnormal terminal axon dysfunction: a case report.

    Science.gov (United States)

    Tomcík, Jan; Dufek, Michal; Hromada, Jan; Rektor, Ivan; Bares, Martin

    2007-12-01

    Miller Fisher syndrome (MFS) is a localized variant of Guillain-Barré syndrome (GBS), characterized by ophthalmoplegia, areflexia, and ataxia. Recent neurophysiological studies have suggested that abnormal terminal axon dysfunction occurs in some cases of Miller Fisher syndrome and Guillain-Barrd syndrome. We present a rare case report of recurrent MFS with abnormal terminal axon dysfunction. To the best of our knowledge, this is the first case report of recurrent MFS with terminal axon dysfunction that persisted up to nine months after the initial presentation of the second attack with positive antiganglioside antibodies and full clinical recovery.

  2. The 1953 Stanley L. Miller Experiment: Fifty Years of Prebiotic Organic Chemistry

    Science.gov (United States)

    Lazcano, Antonio; Bada, Jeffrey L.

    2003-01-01

    The field of prebiotic chemistry effectively began with a publication in Science 50 years ago by Stanley L. Miller on the spark discharge synthesis of amino acids and other compounds using a mixture of reduced gases that were thought to represent the components of the atmosphere on the primitive Earth. On the anniversary of this landmark publication, we provide here an accounting of the events leading to the publication of the paper. We also discuss the historical aspects that lead up to the landmark Miller experiment.

  3. Avaliação do crescimento e desenvolvimento de ratos tratados com Pereskia aculeata, Miller

    OpenAIRE

    Silva,Débora Oliveira da; Dias, Álvaro Guerra; Silva, Adriana Lourenço da

    2012-01-01

    A planta Perskia aculeata, Miller, conhecida no Brasil como ora-pro-nobis, possui elevados teores de proteína, fibras dietéticas totais, minerais e vitaminas. O presente estudo buscou avaliar o crescimento e o desenvolvimento de ratos tratados com dietas contendo a planta Pereskia aculeata, Miller e restrição de proteína. Foram utilizados 24 ratos machos, recém desmamados da linhagem Wistar. Os animais foram divididos em 4 grupos de dieta: padrão de caseína; restrição total de proteína; su...

  4. Halo Scraping, Diffusion and Repopulation MD

    CERN Document Server

    Valentino, G; Bruce, R; Burkart, F; Redaelli, F; Salvachua, B; Previtali, V; Stancari, G; Valishev, A

    2012-01-01

    Beam halo measurements in the LHC were conducted through collimator scrapings in an MD carried out on the 22nd June 2012 for the first time at 4 TeV. The time evolution of losses during a collimator scan provides information on halo diffusion and population. Four scans were performed with two collimators in the vertical and horizontal plane in B1 and B2 respectively, before and after bringing the beams into collisions. During an inward step, the beam losses measured at the BLMs for the first 3 seconds are believed to be dominated by multi-turn halo removal by the collimator jaw. However, a good comparison was found between fits of the diffusion model and the subsequent loss decay. In addition, the fitted diffusion coefficients compare well to the coefficients estimated from the core emittance growth rates as a function of action.

  5. MD1228: Validation of Single Bunch Stability Threshold & MD1751: Instability Studies with a Single Beam

    CERN Document Server

    Carver, Lee Robert; Biancacci, Nicolo; Buffat, Xavier; Iadarola, Giovanni; Lasocha, Kacper; Li, Kevin Shing Bruce; Levens, Tom; Metral, Elias; Salvant, Benoit; Tambasco, Claudia; CERN. Geneva. ATS Department

    2017-01-01

    Instabilities were being routinely observed in B1V during ADJUST. The timing of the instabilities has been localised to shortly after the TOTEM bump has been implemented. The result is emittance blowup which can negatively effect the luminosity output of the fill. This MD aimed to rule out possible sources of the instability (i.e. beam-beam effects or electron cloud) by only taking one single beam to 6.5TeV and going through the full machine cycle. After the implementation of the TOTEM bump, a reduction of the octupole current was performed in order to determine if there was a discrepancy in the threshold between simulations and measurement. As a precursor, the results of the End of Fill MD: Validation of Single Bunch Stability Threshold will also be described.

  6. BI MD studies on April 22nd 2012 (LHC MD-1)

    CERN Document Server

    Baer, T; Boccardi, A; Burger, S; Calvo, E; Dehning, B; Emery, J; Gasior, M; Guerrero, A; Jones, R; Lefevre, T; Gras, JJ; Rabiller, A; Roncarolo, F; Sapinski, M; Steinhagen, R; Trad, G

    2012-01-01

    During the LHC MD block 1 in 2012, eight hours were dedicated to beam instrumentation studies. Such a period was spent mainly for estimating the betatron functions at the location of the transverse profile monitors in IR4 via the K-Modulation method and for characterizing the BSRT extraction mirror heating with high intensity beams. This note discusses the measurements summary, including some final and some preliminary results.

  7. On the Conventionality of Simultaneity and the Huygens-Fresnel-Miller Model of Wave Propagation

    CERN Document Server

    Bock, Robert D

    2016-01-01

    We identify a fundamental space-time invariance principle by combining the thesis of the conventionality of simultaneity with the Hugyens-Fresnel-Miller model of wave propagation. By following the standard gauge prescription, we show that the classical electromagnetic potentials influence the one-way speed of light.

  8. A Tribute to Professor Rene H. Miller - A Pioneer in Aeromechanics and Rotary Wing Flight Transportation

    Science.gov (United States)

    Friedmann, Peretz P.; Johnson, Wayne; Scully, Michael P.

    2011-01-01

    Rene H. Miller (May 19, 1916 January 28, 2003), Emeritus H. N. Slater Professor of Flight Transportation, was one of the most influential pioneers in rotary wing aeromechanics as well as a visionary whose dream was the development of a tilt-rotor based short haul air transportation system. This paper pays a long overdue tribute to his memory and to his extraordinary contributions.

  9. Children Exposed to Drugs in Utero: Their Scores on the Miller Assessment for Preschoolers.

    Science.gov (United States)

    Fulks, Mary-Ann L.; Harris, Susan R.

    1995-01-01

    The Miller Assessment for Preschoolers was administered to 54 children who had been prenatally exposed to drugs. Results indicated a tendency toward the lower end of the spectrum with poorer performance identified on test items measuring tactile, proprioceptive, and vestibular processing and language. (JOW)

  10. Getting Back to the Main Point: A Reply to Miller et al.

    Science.gov (United States)

    Harrison, Allyson G.; Holmes, Alana; Silvestri, Robert; Armstrong, Irene T.

    2015-01-01

    Miller et al. have challenged the findings of our two previous studies, based largely on the assumption that our findings are biased due to the clinical sample used. However, they fail to address the primary tenet of our studies, namely, that clinicians will obtain different scores on the Wechsler Adult Intelligence Scale-IV (WAIS-IV) depending on…

  11. Noble Gases in Nakhla and Three Nakhlites Miller Range 090030, 090032, and 090136

    Science.gov (United States)

    Nagao, K.; Haba, M. K.; Park, J.; Choi, J.; Baek, J. M.; Park, C.; Lee, J. I.; Lee, M. J.; Mikouchi, T.; Nyquist, L. E.; Herzog, G. F.; Turrin, B. D.; Lindsay, F. N.; Delaney, J. S.; Swisher, C. C., III

    2016-08-01

    Noble gas compositions of the Miller Range nakhlites release Kr and Xe with low 84Kr/132Xe of ≤1 and high 129Xe/132Xe of 1.95-2.13 at low heating temperature (300-400°C). The gases would be heavily fractionated martian atmosphere trapped in aqueously altered materials.

  12. Children Exposed to Drugs in Utero: Their Scores on the Miller Assessment for Preschoolers.

    Science.gov (United States)

    Fulks, Mary-Ann L.; Harris, Susan R.

    1995-01-01

    The Miller Assessment for Preschoolers was administered to 54 children who had been prenatally exposed to drugs. Results indicated a tendency toward the lower end of the spectrum with poorer performance identified on test items measuring tactile, proprioceptive, and vestibular processing and language. (JOW)

  13. Getting Back to the Main Point: A Reply to Miller et al.

    Science.gov (United States)

    Harrison, Allyson G.; Holmes, Alana; Silvestri, Robert; Armstrong, Irene T.

    2015-01-01

    Miller et al. have challenged the findings of our two previous studies, based largely on the assumption that our findings are biased due to the clinical sample used. However, they fail to address the primary tenet of our studies, namely, that clinicians will obtain different scores on the Wechsler Adult Intelligence Scale-IV (WAIS-IV) depending on…

  14. Circuits of Spectacle: The Miller Brothers' 101 Ranch Real Wild West

    Science.gov (United States)

    Fields, Alison

    2012-01-01

    The Miller Brothers' 101 Ranch Real Wild West show ran from 1906 to 1931, outlasting the famous Buffalo Bill's Wild West show by more than a decade. From its beginnings in Oklahoma Territory, the Real Wild West show traveled national and international circuits and built a broad roster of performers, including more than 150 American Indians. During…

  15. MD5算法在Web开发中的应用%Application of MD5 in Web Exploitation

    Institute of Scientific and Technical Information of China (English)

    刘啸

    2014-01-01

    介绍了MD5加密技术在Web上的一些应用,给出了MD5加密实现密码在internet上安全传输的完整解决办法,给出了客户端(JavaScript)和服务器端(JavaBeans) MD5算法的实现.

  16. Obituary: Richard L. (Dick) Walker, Jr., 1938-2005

    Science.gov (United States)

    Pier, Jeffrey R.; Mason, Brian

    2005-12-01

    Koch Center for Science, Math, and Technology at Deerfield Academy in Massachusetts. He also consulted with James Turrell, providing astronomical position information for the design of the Roden Crater Project outside of Flagstaff. While he will be remembered for his significant scientific contributions to the field of astronomy, those who knew Dick, both scientists and non-scientists alike, will probably remember him best for his humility, his humanity, and his loyal and abiding friendship. He was a man with a terrific sense of humor and an infectious laugh. It was always an honor and pleasure to be in his company. Richard L. Walker, Jr. is survived by his wife, Patricia, two daughters from his first marriage: Brenda Walker of Las Vegas, NV, and Pamela Hepburn of Holland, OH, as well as four children from Patricia's first marriage: Doug Browning of Lake Havasu City, AZ, Michael Browning of Kingman, AZ, Kim Bructo of Orient, OH, and Jennifer Brown of Lake Havasu City, AZ. He is also survived by ten grandchildren and three great-grandchildren. He was preceded in death by his father Richard, mother Mary, and daughter, Paula Jean Elizabeth Stone.

  17. Obituary: Ralph Robert Robbins, Jr., 1938-2005

    Science.gov (United States)

    Hemenway, Mary Kay; Jefferys, William H.; Lambert, David L.

    2007-12-01

    Ralph Robert Robbins, Jr., died on 2 December 2005, in Kyle, Texas. His wife, Maria Elena Robbins, his daughters Julia Robbins Kelso and Stephanie Juarez Balles, his son Matthew Juarez, and five grandchildren survive him. Bob was on the faculty at the University of Texas from 1968 until his retirement in 2003. Bob was born in Wichita, Kansas, on 2 September 1938, the only son of Mildred and Ralph Robert Robbins, Sr. Guided by his high school's policy to provide a practical education to children of working-class parents, Bob began high school with a heavy dose of vocational courses until the results of a test indicated his special talent in mathematics. He was awarded a full scholarship to Yale University, graduating magna cum laude in mathematics in 1960. He won the Warner Prize in Mathematics at Yale that year. He received his Ph.D. in 1966 with a dissertation entitled "The Triplet Spectrum of Neutral Helium in Expanding Nebulae" from the University of California at Berkeley. His interest in college teaching was ignited at this time through summer teaching positions at San Mateo California Junior College and the Ohio State University. Following a year at Texas as a McDonald Observatory Post-doctoral Fellow, Bob taught for a year in the physics department of the University of Houston before returning to the University of Texas at Austin as an Assistant Professor of Astronomy in 1968. He was promoted to Associate Professor in 1972. Bob's research in the early 1970s on theoretical studies of helium was of vital importance to astronomers for over three decades. These pioneering calculations became vital to observational astronomers in the mid-1990s as interest grew in the primordial helium produced by the Big Bang. Bob's interest and influence in education was international in scope. In the summers 1968-1970, he was a government consultant in Mathematics in East Pakistan (now Bangladesh). He consulted with the government that was preparing a master plan for technical

  18. Obituary: George Hamilton Bowen Jr. (1925-2009)

    Science.gov (United States)

    Willson, Lee Anne; Struck, Curtis

    2011-12-01

    Our colleague and collaborator George Hamilton Bowen, Jr., passed away November 1, 2009 in Ames, Iowa. George was born June 20, 1925 in Tulsa, Oklahoma to George and Dorothy (Huntington) Bowen. He married Marjorie Brown June 19, 1948 in Redondo Beach, California; they had five children, with eight grandchildren and five great-grandchildren at the time of his death. George H. Bowen's third or perhaps his fourth career was in astronomy. He was drafted into the navy in 1944, at the end of his first year as a student at Caltech, and ended his war-time service as an electronic technician on the aircraft carrier Shangri-La. He later said "In just nine months, starting from scratch (Ohm's law!), we learned an amazing amount - not by memorization, of course, but by study and real understanding of the basic function of the most advanced AC circuits then being used for instrumentation, measurements, communications, control systems, and much more." He gained a confidence that he could quickly and accurately diagnose and solve technical problems that stood him well in future work. One accomplishment he took particular pride in was figuring out how the radar control used cams and gears to solve the trigonometry for accurate pointing. He also described how the captain was alarmed when weather conditions changed so that refraction no longer showed them distant, small boats around the curvature of Earth. After the war, George Bowen returned to undergraduate and eventually graduate study at Caltech, where he was recruited to the biophysics research group headed by future Nobel Laureate Max Delbrück. George often described his joy in working with these first-rate scientists and finding himself accepted as a part of the effort. He finished his BS with honors in 1949 and his PhD in 1953 with a thesis on "Kinetic Studies on the Mechanism of Photoreactivation of Bacteriophase T2 Inactivated by Ultraviolet Light" involving work with E Coli. This work was supported by grants from the U

  19. LHC MD 1279: Bunch Flattening in Physics

    CERN Document Server

    AUTHOR|(CDS)2073675; Baudrenghien, Philippe; Esteban Muller, Juan; Shaposhnikova, Elena; CERN. Geneva. ATS Department

    2017-01-01

    Vertex reconstruction is not accurate enough for LHCb when the bunch length in physics shrinks below about 0.9 ns. The end-of-fill MD studies presented here proved that bunch flattening using sinusoidal RF modulation is a loss-free method to increase the r.m.s. bunch length and flatten the bunch profile. Furthermore, the optimum modulation parameters to be used in physics have been identified. Subsequently, bunch flattening in physics was used operationally with a modulation frequency of 98.75 % of the central synchrotron frequency and 0.6 modulation amplitude, resulting in a 150-200 ps increase in the BQM-measured bunch length. A ‘mid-of-fill’ test at arrival to flat top revealed that also the bunch distribution created by the controlled emittance blow-up during the ramp is affected when bunch flattening is applied. The measurements took place on 17th June and the 4th, 7th and 22nd July 2016. Operational cases are shown as well.

  20. Leroy D Vandam, MD: an anesthesia journey.

    Science.gov (United States)

    Ortega, Rafael A

    2005-08-01

    Leroy D Vandam, MD was a remarkable man--an intricate amalgamation of an artist, scientist, and physician. He was a bastion of medical historical knowledge. Dr Vandam became a most influential anesthesiologist, some say, a giant. He was an example of someone who, with resolve, overcame adversity. His artwork is displayed in countless places, and several of his paintings form part of the Wood Library Museum Heritage Series. Dr Vandam was first a surgeon, but he abandoned surgery and pursued a career in anesthesiology under the leadership of Robert Dripps. He completed his residency training at the University of Pennsylvania and joined its staff in 1949. When he arrived at Brigham and Women's Hospital in the 1950s as director of anesthesia, he embarked on one of the most illustrious careers in American anesthesiology. Dr Vandam published more than 250 original articles, chapters, abstracts, and other reports on a wide variety of subjects including history, art, and pharmacology. His classic article on the complications of neuroaxial blocks is a seminal work in anesthesiology. This article describes how an anesthesiologist who shared an interest with Dr Vandam in the history of anesthesiology came to produce a movie based on his career, the evolution of anesthesia equipment, and the transformation of our specialty.

  1. Orbit Feedback Operation with RCBX (MD 1209)

    CERN Document Server

    Wenninger, Jorg; Nisbet, David; Ponce, Laurette; Louro Alves, Diogo Miguel; CERN. Geneva. ATS Department

    2017-01-01

    The LHC Orbit Feedback (OFB) is able to drive any orbit corrector circuit (COD) to steer the LHC orbit. But during the first feedback tests in 2010, all attempts to use the common triplet orbit correctors (MCBX) failed because the QPS system installed to protect those magnets triggered power aborts as soon as the OFB steered the beam with those CODs. The reason was most likely the violation of the RCBX circuit acceleration limits. For this reason the MCBX orbit correctors were never driven by the OFB in regular operation. Although the performance of the OFB is generally excellent, the quality of the beam steering around IRs could be improved if the OFB could correct the orbit with the MCBX to counteract locally triplet quadrupole movements. The aim of this MD was to make a new attempt to use the MCBX in the OFB. The test was successful at injection (no circuit trip) and failed during the ramp (QPS power abort). The PC voltages and QPS Ures signals revealed the presence of voltage spikes with a period of 10~s...

  2. Waiting time distribution in M/D/1 queueing systems

    DEFF Research Database (Denmark)

    Iversen, Villy Bæk; Staalhagen, Lars

    1999-01-01

    The well-known formula for the waiting time distribution of M/D/1 queueing systems is numerically unsuitable when the load is close to 1.0 and/or the results for a large waiting time are required. An algorithm for any load and waiting time is presented, based on the state probabilities of M/D/1...

  3. BI MD studies on August 25th 2011

    CERN Document Server

    Belohrad, D; Boccardi, A; Calvo, E; Dehning, B; Favier, M; Emery, J; Guerrero, A; Lefevre, T; Gras, JJ; Jeff, A; Soby, L; Rabiller, A; Roncarolo, F; Sapinski, M; Steinhagen, R; Mateo, CM

    2011-01-01

    This note contains the preliminary results of the LHC MD that took place on 25-Aug-2011 (from 5 a.m. to 1 p.m.), dedicated to study Beam Loss Monitors (BLM), Wire Scanners (WS), Synchrotron Radiation (BSRT), Beam Position Monitors (BPM), and Beam Gas Ionization (BGI) monitors. The MD aimed at performing different studies on the individual monitors.

  4. MD290: Q4 IP6 Quench Level

    CERN Document Server

    Bednarek, Mateusz Jakub; Lechner, Anton; CERN. Geneva. ATS Department

    2016-01-01

    The detailed program proposed for the LHC Machine Development concerning a quench induced by fast losses on the MQY.4L6 quadrupole is presented. The merit of the MD, the necessary modifications of the machine protection systems are presented together with a preliminary analysis of the MD results.

  5. MD5密码极速爆破

    Institute of Scientific and Technical Information of China (English)

    飘零雪

    2009-01-01

    MD5加密技术对我们来说并不陌生,通过MD5值可以校验下载软件的安全性,而且在很多系统中,用户的密码是以MD5值的方式保存的,用户登录时系统是把用户输入的密码计算成MD5值,然后再去和系统中保存的MD5值进行比较,以验证该用户的合法性。MD5值虽看似很安全,但也并非无懈可击,使用“超速md5破解工具”即可简单快捷地尝试解密MD5。

  6. Single-block collision attack on MD5

    NARCIS (Netherlands)

    Stevens, M.M.J.

    2012-01-01

    In 2010, Tao Xie and Dengguo Feng \\cite{cryptoeprint:2010:643} constructed the first single-block collision for MD5 consisting of two 64-byte messages that have the same MD5 hash. Details of their attack, developed using what they call an evolutionary approach, has not been disclosed ``for security

  7. Chosen-Prefix Collisions for MD5 and Applications

    NARCIS (Netherlands)

    Stevens, M.M.J.; Lenstra, A.K.; Weger, B. de

    2012-01-01

    We present a novel, automated way to find differential paths for MD5. Its main application is in the construction of \\emph{chosen-prefix collisions}. We have shown how, at an approximate expected cost of $2^{39}$ calls to the MD5 compression function, for any two chosen message prefixes $P$ and $P'$

  8. 33 CFR 110.72 - Blackhole Creek, Md.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Blackhole Creek, Md. 110.72... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.72 Blackhole Creek, Md. The waters on the west side of Blackhole Creek, a tributary of Magothy River, southwest of a line bearing 310°30′ from the most...

  9. A Discourse Analysis of the Centered and Critical Scholar-Activism of Martin Luther King Jr.

    OpenAIRE

    Keatts, Quenton

    2010-01-01

    The purpose of this project is to investigate the often neglected research concerning the Reverend Dr. Martin Luther King, Jr. and his scholar-activism. This project is intended to look for evidence of intellectual leadership within Kingâ s writings in an effort to classify King within the Scholar-Activist paradigm in Africana Studies. Further, the aim is to examine Martin Luther King, Jr. from the critical and centered Scholar-Activist paradigm of Africana Studies based on an analysis of ...

  10. Has the Dream Been Fulfilled? Dr. Martin Luther King, Jr. & President Barack Hussein Obama

    Science.gov (United States)

    Robinson, Nichelle Boyd; Moore, Virginia J.; Williams-Black, Thea H.

    2015-01-01

    Equality for all was the dream of Dr. Martin Luther King, Jr. and he knowingly laid the foundation for and inspired the first African-American President of the United States of America, Barack Hussein Obama, who also had the dream of "Change" for America. These men exhibited how working together can make dreams become reality. For the…

  11. Ability of Lactobacillus plantarum JR64 isolated from noni juice in lowering Cholesterol in vivo

    Directory of Open Access Journals (Sweden)

    Lanjar Sumarno

    2011-07-01

    Full Text Available Recently public’s attention to the importance of healthy food increases rapidly. Probiotic based food exploiting lactic acid bacteria is among the healthy food. Lactobacillus plantarum JR64 isolate from Morinda citrifolia fruit was assessed for its probiotic in-vivo by using Wistar  Rat. The purpose of this research was to study the ability of probiotic Lactobacillus plantarum JR64 in lowering serum LDL (Low Density Lipoprotein of Wistar Rat. Twenty Rats were grouped into 4, each group consisted of 5 Rats. First Group was a negative control  given standard normal diet of 20 gr/day plus aquadest. Second Grup was a positive control given cholesterol normal diet 20 gr /day plus Propil Tio Urasil (PTU 60 mg/kg body weight/day. Third Group was supplemented with normal diet 20 gr /day plus Propil Tio Urasil (PTU 60 mg  kg body weight /day and  1012 CFU Lactobacillus plantarum JR64. Fourth Group was the same as third Group unless the probiotic using commercial probiotic Lactobacillus bulgariccus at 1012 CFU. Blood samples were withdrawn for measurement of total cholesterol, triglyceride, High Density Lipoprotein (HDL, and Low Density Lipoprotein (LDL cholesterol every week and measured by using spectrophotometer with 546 nanometers wavelength. The results show that probiotic Lactobacillus plantarum JR64 isolated from noni juice significantly (p < 0,01 reduce Low Density Lipoprotein (LDL and Triglyceride in vivo  and tend to reduce High Density Lipoprotein (HDL and total cholesterol.

  12. Commemoration of Dr. Martin Luther King, Jr., January 15, 1929-April 4, 1968. Revised.

    Science.gov (United States)

    Montgomery County Public Schools, Rockville, MD.

    Developed in honor of Dr. Martin Luther King, Jr., this is a short collection of suggested activities to teach black awareness in the elementary and secondary grades through King's philosophy. An introductory biographical sketch of King and an article about his accomplishments are provided. Activities are divided into grade-level ranges for the…

  13. Fighting Fair. Dr. Martin Luther King, Jr. for Kids. Second Edition.

    Science.gov (United States)

    Schmidt, Fran; Friedman, Alice

    This curriculum guide for grades 4 through 9 uses the life and work of Dr. Martin Luther King, Jr., to teach conflict resolution and to explore the philosophy of non-violence for daily life. To enable students to learn and apply non-violence, it must be modeled in a classroom environment that builds trust and a sense of community. Each of the…

  14. Abuse of Power? : J. Edgar Hoover vs. Robert Kennedy and Martin Luther King, Jr.

    OpenAIRE

    Isaksen, Vigdis

    2002-01-01

    In this thesis I have looked at how J. Edgar Hoover came to power as Director of the FBI, and how he later used that power against Attorney General Robert Kennedy and SCLC leader Martin Luther King, Jr. I have further analyzed the reasons and motives for Hoover's actions by, among other things, making a psychological profile on the Director.

  15. Sharing the Gift of Jazz: An Interview with Willie L. Hill Jr.

    Science.gov (United States)

    Howe, Brad

    2011-01-01

    This article presents an interview with Willie L. Hill Jr., founder and director of the Society for Jazz Education. Currently a professor of music education at the University of Massachusetts-Amherst and the director of the UMass Fine Arts Center, Hill has served as director of education for the Thelonious Monk Institute of Jazz. He is a past…

  16. Addressing Curriculum Deficiencies on Martin Luther King, Jr. through Computer Assisted Instruction and Multimedia Resources.

    Science.gov (United States)

    Kim, James S.

    Students need to see past heroes as real people who struggled with ordinary problems in order to see the relevancy of studying history and to act practically upon the lessons that each leader teaches them. This study attempts to answer two questions relating to Martin Luther King, Jr.: (1) What do we teach our children about King? and (2) Can we…

  17. Steam System Efficiency Optimized After J.R. Simplot Fertilizer Plant Receives Energy Assessment

    Energy Technology Data Exchange (ETDEWEB)

    None

    2008-07-01

    The J.R. Simplot Company's Don Plant in Pocatello, Idaho, optimized boiler operation, improved condensate recovery, and fixed steam traps and leaks for a simple payback of 6.5 months. Results are being shared with other Simplot facilities and other recommendations identified during the assessment are under consideration.

  18. Steam System Efficiency Optimized After J.R. Simplot Fertilizer Plant Receives Energy Assessment

    Energy Technology Data Exchange (ETDEWEB)

    2008-07-01

    This case study describes how the J.R. Simplot company's Don Plant in Pocatello, Idaho, achieved annual savings of $335,000 and 75,000 MMBtu, with a simple payback of 6.5 months, after receiving a DOE Save Energy Now energy assessment.

  19. "Qualitative Liberalism": Arthur Schlesinger, Jr. and the Persuasive Uses of Definition and History.

    Science.gov (United States)

    Depoe, Stephen P.

    1989-01-01

    Applies the concepts of persuasive definition, ideograph, and ideological history in an analysis of Arthur Schlesinger, Jr.'s, discourse. Uses this analysis to enhance understanding of how the strategic definition of terms such as "liberal" can influence the ongoing struggle to set presumptions in American political life. (SR)

  20. Abuse of Power? : J. Edgar Hoover vs. Robert Kennedy and Martin Luther King, Jr.

    OpenAIRE

    Isaksen, Vigdis

    2002-01-01

    In this thesis I have looked at how J. Edgar Hoover came to power as Director of the FBI, and how he later used that power against Attorney General Robert Kennedy and SCLC leader Martin Luther King, Jr. I have further analyzed the reasons and motives for Hoover's actions by, among other things, making a psychological profile on the Director.

  1. Mounting a Curricular Revolution: An Interview with Henry Louis Gates, Jr.

    Science.gov (United States)

    von Zastrow, Claus

    2009-01-01

    This article presents an interview with Henry Louis Gates, Jr., Harvard professor and cultural critic who has captured 25 million viewers with his PBS documentary series, African American Lives (WNET). Using genealogical research and DNA science, Gates traces the family history of 19 famous African Americans. What results is a rich and moving…

  2. Sharing the Gift of Jazz: An Interview with Willie L. Hill Jr.

    Science.gov (United States)

    Howe, Brad

    2011-01-01

    This article presents an interview with Willie L. Hill Jr., founder and director of the Society for Jazz Education. Currently a professor of music education at the University of Massachusetts-Amherst and the director of the UMass Fine Arts Center, Hill has served as director of education for the Thelonious Monk Institute of Jazz. He is a past…

  3. Has the Dream Been Fulfilled? Dr. Martin Luther King, Jr. & President Barack Hussein Obama

    Science.gov (United States)

    Robinson, Nichelle Boyd; Moore, Virginia J.; Williams-Black, Thea H.

    2015-01-01

    Equality for all was the dream of Dr. Martin Luther King, Jr. and he knowingly laid the foundation for and inspired the first African-American President of the United States of America, Barack Hussein Obama, who also had the dream of "Change" for America. These men exhibited how working together can make dreams become reality. For the…

  4. Martin Luther King, Jr.: A Lesson with Interdisciplinary Connections for Middle-Level Music Students.

    Science.gov (United States)

    Early, Mary Frances; Terry, Cynthia

    This lesson begins with a very brief biography of Martin Luther King, Jr. The lesson identifies its educational objectives; addresses National Standards for Music Education; lists materials needed; details six step-by-step classroom procedures for lesson implementation; and provides curriculum connections for language arts, visual art, physical…

  5. Martin Luther King, Jr. and the Power of Nonviolence. [Lesson Plan].

    Science.gov (United States)

    National Endowment for the Humanities (NFAH), Washington, DC.

    This lesson plan introduces students in grades 6-8 to Martin Luther King Jr.'s philosophy of nonviolence and the teachings of Mohandas K. Gandhi that influenced King's views. After considering the political impact of this philosophy, students explore its relevance to personal life. In these 6 lessons students will: (1) examine the philosophy of…

  6. Let Freedom Ring: The Life & Legacy of Martin Luther King, Jr. [Lesson Plan].

    Science.gov (United States)

    National Endowment for the Humanities (NFAH), Washington, DC.

    This lesson plan teaches students about the life and work of Martin Luther King, Jr. Students listen to a brief biography, view photographs of the March on Washington, and read a portion of King's "I Have a Dream" speech. After studying Dr. King's use of imagery and allusion, students create original poetic phrases about freedom and…

  7. Draft Genome Sequences of Legionella pneumophila JR32 and Lp01 Laboratory Strains Domesticated in Japan

    Science.gov (United States)

    Maita, Chinatsu; Matushita, Mizue; Okubo, Torahiko; Matsuo, Junji; Miyake, Masaki; Nagai, Hiroki

    2016-01-01

    We report here the draft genome sequences of two Legionella pneumophila variant strains (JR32 and Lp01_666) originally derived from a Philadelphia-1 clinical isolate, domesticated in Japan, with distinct susceptibility to amoebae. Detailed genomic analysis will allow us to better understand Legionella adaptation and survival mechanisms in host cells. PMID:27491976

  8. Henry David Thoreau, Martin Luther King Jr., and the American Tradition of Protest.

    Science.gov (United States)

    Powell, Brent

    1995-01-01

    Maintains that Henry David Thoreau and Martin Luther King, Jr. fundamentally altered the tradition of protest and reform. Compares and contrasts the role of each man in U.S. social and constitutional history. Concludes that while Thoreau lacked the broad influence of King, his writings influenced both King and Mohandas Gandhi. (CFR)

  9. The Rhetorical Construction of Time in Martin Luther King, Jr.'s "Letter from Birmingham Jail."

    Science.gov (United States)

    Lee, Ronald E.

    1991-01-01

    Explores the rhetorical use of time in Martin Luther King, Jr.'s "Letter from Birmingham Jail." Offers an explanation of the ideological heritage that temporarily unifies the discourse. Describes the letter's recent, historical, and spiritual time frames, accounts for the ideological purpose each serves, and explains on what ground they…

  10. Martin Luther King, Jr. Borrows a Revolution: Argument, Audience, and Implications of a Secondhand Universe.

    Science.gov (United States)

    Miller, Keith D.

    1986-01-01

    Examines features of and sources for the discourse of Martin Luther King, Jr., as they relate to the language and assumptions favored by his listeners and readers in an effort to understand how speakers and writers can successfully argue from premises that audiences accept. Indicates how an understanding of King can help in composition…

  11. The Fierce Urgency of now: Honoring Martin Luther King, Jr. in and out of the Classroom.

    Science.gov (United States)

    Kazemek, Francis E.

    1988-01-01

    Explores how educators and their students can best honor Martin Luther King, Jr.'s, memory by using his life and works as a catalyst for acting upon school and society in a way that fosters social change. (Author/BJV)

  12. Children's Books on Martin Luther King, Jr. Offer a One-Dimensional View.

    Science.gov (United States)

    Banfield, Beryle

    1985-01-01

    Reviews children's books, teacher references, mini-plays, and curriculum resources that relate to the life of Martin Luther King, Jr. Reports that most of these sources ignore growth and changes within King's life and thought, the role models who shaped his philosophy, or his participation in issues such as the Vietnam War and poverty. (KH)

  13. MD-PhD training: looking back and looking forward.

    Science.gov (United States)

    Bonham, Ann C

    2014-01-01

    MD-PhD programs provide rigorous, integrated training for physician-scientists, enabling them to frame scientific questions in unique ways and to apply clinical insight to fundamental science. Few would question the influential contributions of MD-PhD physician-scientists in advancing medical science. In this issue of Academic Medicine, Jeffe et al affirm high levels of excellence in educational outcomes from MD-PhD training programs at U.S. MD-granting medical schools, especially programs that receive funding from the NIH Medical Scientist Training Program (MSTP). The author of this commentary observes that, in the face of current economic pressures, comprehensive, longitudinal national outcomes data from MSTP- and non-MSTP-funded MD-PhD programs will help verify the value provided by MD-PhD physician-scientists. She proposes that MD-PhD programs should better prepare the next generation of physician-scientists for future research environments, which will provide new technologies, venues, and modalities. These research environments will be more closely integrated within health care delivery systems, extend into diverse communities and regions, and employ complex technologies. MD-PhD physician-scientists also will train and gain expertise in broadening areas of research, such as health policy, health economics, clinical epidemiology, and medical informatics. Program leaders are ideally situated to foster innovative learning environments and methodologies. By sharing their innovations, they can help ensure production of a diverse MD-PhD physician-scientist workforce, prepared to engage in myriad research opportunities to meet patient and population needs in a new environment.

  14. 78 FR 10172 - Lisa Anne Cornell and G. Ware Cornell, Jr. v. Princess Cruise Lines, Ltd. (Corp), Carnival PLC...

    Science.gov (United States)

    2013-02-13

    ... Lisa Anne Cornell and G. Ware Cornell, Jr. v. Princess Cruise Lines, Ltd. (Corp), Carnival PLC, and..., Jr., hereinafter ``Complainants,'' against Princess Cruise Lines, Ltd (Corp), Carnival plc, and... common carrier for hire of passengers from ports in the United States;'' Respondent Carnival plc ``is...

  15. J.R. SIMPLOT EX-SITU BIOREMEDIATION TECHNOLOGY FOR TREATMENT OF TNT-CONTAMINATED SOILS - INNOVATIVE TECHNOLOGY EVALUATION REPORT

    Science.gov (United States)

    This report summarizes the findings of the second evaluation of the J.R. Simplot Ex-situ Bioremediation Technology also known as the Simplot Anaerobic Bioremediation (SABRE™) process. This technology was developed by the J.R. Simplot Company to biologically degrade nitroaromatic...

  16. J.R. SIMPLOT EX-SITU BIOREMEDIATION TECHNOLOGY FOR TREATMENT OF DINOSEB-CONTAMINATED SOILS - INNOVATIVE TECHNOLOGY REPORT

    Science.gov (United States)

    This report summarizes the findings of an evaluation of the J.R. Simplot Ex-Situ Bioremediation Technology on the degradation of dinoseb (2-set-butyl-4,6-dinitrophenol) an agricultural herbicide. This technology was developed by the J.R. Simplot Company (Simplot) to biologically ...

  17. HPTLC profile of aqueous extract of different chromatographic fractions of Aloe barbadensis Miller

    Directory of Open Access Journals (Sweden)

    Nishant Kumar Ojha

    2012-05-01

    Full Text Available Objective: To establish the fingerprint profile of Aloe barbadensis Miller by using High Performance Thin Layer Chromatography (HPTLC technique. Methods: after optimization of solvent system by Thin Layer Chromatography, different fractions of aqueous extract of Aloe was collected by column chromatography and the fingerprinting was done by High Performance Thin Layer Chromatography (HPTLC Results: solvent system of methanol:chloroform :: 1:1 was found appropriate for fractionation by column chromatography. Total seven fractions were collected and they were analysed by HPTLC. Distinct spectra of different constituents were obtained for each fraction. Conclusions: HPTLC fingerprinting of Aloe barbadensis Miller may be useful in characterization of different phytochemicals found in this species. It may also be useful in differentiating the species from the adulterant and act as a biochemical marker for this medicinally important plant in the pharmaceutical industry.

  18. Nitrogen isotope fractionations in the Fischer-Tropsch synthesis and in the Miller-Urey reaction

    Science.gov (United States)

    King, C.-C.; Clayton, R. N.; Hayatsu, R.; Studier, M. H.

    1979-01-01

    Nitrogen isotope fractionations have been measured in Fischer-Tropsch and Miller-Urey reactions in order to determine whether these processes can account for the large N-15/N-14 ratios found in organic matter in carbonaceous chondrites. Polymeric material formed in the Fischer-Tropsch reaction was enriched in N-15 by only 3 per mil relative to the starting material (NH3). The N-15 enrichment in polymers from the Miller-Urey reaction was 10-12 per mil. Both of these fractionations are small compared to the 80-90 per mil differences observed between enstatite chondrites and carbonaceous chondrites. These large differences are apparently due to temporal or spatial variations in the isotopic composition of nitrogen in the solar nebula, rather than to fractionation during the production of organic compounds.

  19. Effect of Hydroalcoholic Extract of Cydonia oblonga Miller (Quince) on Sexual Behaviour of Wistar Rats.

    Science.gov (United States)

    Aslam, Muhammad; Sial, Ali Akbar

    2014-01-01

    Cydonia oblonga Miller (quince) is regarded as a potent libido invigorator in Tib-e-Nabvi and Unani System of Medicine. This study was carried out to evaluate the aphrodisiac activity of the hydroalcoholic extract of the fruits of Cydonia oblonga Miller (quince) in Wistar rats. The extract was administered orally by gavage in the dose of 500 mg/kg and 800 mg/kg body weight per day as a single dose for 28 days. The observed parameters were mounting frequency, assessment of mating performance, and orientation activities towards females, towards the environment, and towards self. The results showed that after administration of the extract mounting frequency and the mating performance of the rats increased highly significantly (P < 0.01). The extract also influenced the behaviour of treated animals in comparison to nontreated rats in a remarkable manner, making them more attracted to females. These effects were observed in sexually active male Wistar rats.

  20. Effect of Hydroalcoholic Extract of Cydonia oblonga Miller (Quince on Sexual Behaviour of Wistar Rats

    Directory of Open Access Journals (Sweden)

    Muhammad Aslam

    2014-01-01

    Full Text Available Cydonia oblonga Miller (quince is regarded as a potent libido invigorator in Tib-e-Nabvi and Unani System of Medicine. This study was carried out to evaluate the aphrodisiac activity of the hydroalcoholic extract of the fruits of Cydonia oblonga Miller (quince in Wistar rats. The extract was administered orally by gavage in the dose of 500 mg/kg and 800 mg/kg body weight per day as a single dose for 28 days. The observed parameters were mounting frequency, assessment of mating performance, and orientation activities towards females, towards the environment, and towards self. The results showed that after administration of the extract mounting frequency and the mating performance of the rats increased highly significantly P<0.01. The extract also influenced the behaviour of treated animals in comparison to nontreated rats in a remarkable manner, making them more attracted to females. These effects were observed in sexually active male Wistar rats.

  1. MD5加密算法的研究

    Institute of Scientific and Technical Information of China (English)

    许琪

    2014-01-01

    MD5加密算法做为散列函数的一个重要算法,在文件校验、数字签名等诸多领域有着广泛的应用.虽然MD5加密算法是单向算法,但其仍无法抵御差分攻击和查字典攻击.文章在分析了差分攻击原理的基础上,阐述了MD5加密算法采用差分攻击产生碰撞的方法.

  2. The Achromatic Telescopic Squeezing (ATS) MD part III

    CERN Document Server

    Fartoukh, S; Goddard, B; Hofle, W; Jacquet, D; Kruk, G; Lamont, M; de Maria, R; Miyamoto, R; Mueller, G; Pojer, M; Ponce, L; Redaelli, S; Ryckx, N; Steinhagen, R; Strzelczyk, M; Vanbavinckhove, G; Wenninger, J

    2011-01-01

    This note highlights the results obtained during the third so-called ATS MD which took place in 2011. The goal of this MD was extremely challenging, targeting a pre-squeezed beta* of 40 cm in ATLAS and CMS, followed by a telescopic squeeze of these two insertions to finally reach a beta* of 10 cm both at IP1 and IP5. Due to the rather poor machine availability during the MD period, the time initially allocated to the ATS studies was hardly cut by a factor of 2, and "only" the achromatic pre-squeeze down to beta*=40 cm was demonstrated with beam.

  3. Utilization of Lavandula angustifolia Miller extracts as naturalrepellents, pharmaceutical and industrial auxiliaries

    Directory of Open Access Journals (Sweden)

    AYOE YUSUFOGLU

    2004-01-01

    Full Text Available Essential oils, absolutes and concretes were prepared from the flowers and leaves of the plant Lavandula angustifolia Miller cultivated in the Bosphorus region of Istanbul, Turkey. The difference in the chemical composition of the mentioned extracts was investigated and compared by using a combination of capillary GC-MS with the aim of offering them as repellent, pharmaceutical and industrial auxiliaries. The IR-spectra, the yields and the physico-chemical data of the extracts were also analysed.

  4. Abnormalities of neuromuscular transmission in patients with Miller-Fisher syndrome.

    Science.gov (United States)

    Menon, Parvathi; Mahant, Neil; Vucic, Steve

    2012-11-01

    The mechanism of motor weakness in patients with Miller-Fisher syndrome (MFS) remains to be fully elucidated. We performed stimulated single fibre electromyography (sSFEMG) in a clinically weak frontalis muscle in a patient with MFS. Stimulate single fiber EMG revealed increased jitter in over 50% of the apparent single fibre action potentials from the frontalis muscle in addition to increased mean jitter. The findings in the present study suggest dysfunction of neuromuscular transmission in patients with MFS.

  5. Evaluation of respiratory effects in miners and millers exposed to talc free of asbestos and silica.

    OpenAIRE

    Wegman, D H; Peters, J M; Boundy, M G; SMITH, T. J.

    1982-01-01

    Miners and millers of talc ore, free from asbestos and silica, were examined for respiratory effects. A study of 116 subjects included the modified British Medical Research Council respiratory symptom questionnaire, simple spirometry, chest radiography, and limited examination of the chest. A one-year follow-up evaluation was performed on 103 subjects. Of the 12 subjects whose chest radiographs showed small round or irregular opacities (perfusion 1/0 or greater), five had never smoked cigaret...

  6. A Study on Daisy Miller The Tragic Fate of the Heroine and its Reasons

    Institute of Scientific and Technical Information of China (English)

    张自勉; 王明媚; 卢德美

    2014-01-01

    Daisy Miller is an 1878 novella about an American girl by Henry James;This paper, based on the textual analysis of the novel is an effort to study the tragic fate of heroine and its reason through a comparative study of it. Two common reasons of the tragic destiny will be discussed in the paper:one, the oppressive environment;the other, the hero ’s inaction.

  7. Post project evaluation of Miller Creek (Marin, CA) restoration : vegetation survival

    OpenAIRE

    Ting, Jantrue; Pope-Daum, Caitilin

    2004-01-01

    We evaluated the survival of planted riparian vegetation within a restored reach of Miller Creek in Marin County, CA, and analyzed survey results to identify factors affecting tree survival. We surveyed three plots approximately 100 feet square within the restored reach. Of the three plots surveyed, the most downstream plot has the highest plant survival rates. The survival rates of tree species in the three plots, from upstream to downstream, were 35%, 43%, and 88%, respectively. Despite ear...

  8. Mycocoenology in Abies alba Miller woods of central-southern Tuscany (Italy)

    OpenAIRE

    Angela Laganà; Elena Salerni; Carla Barluzzi; Claudia Perini; Vincenzo de Dominicis

    2014-01-01

    Numerous reports indicate that fir woods in central and northern Europe have recently been damaged by increasing pollution. It has been demonstrated that fungi can be good bioindicators of forest health status. In polluted areas the production of fruit bodies generally declines and the fungal biodiversity, especially of symbiotic species, is reduced. Here we report the results of a survey of the fungal and plant communities in woods of Abies alba Miller in central-southern Tuscany, already st...

  9. Review: Miller, Michelle Ann (2009, Rebellion and Reform in Indonesia – Jakarta’s Security and Autonomy Policies in Aceh

    Directory of Open Access Journals (Sweden)

    Antje Missbach

    2009-01-01

    Full Text Available Review of the monograph: Miller, Michelle Ann, Rebellion and Reform in Indonesia – Jakarta’s Security and Autonomy Policies in Aceh, London/ New York: Routledge, 2009, ISBN 13: 978-0-415-45467-4, 240 pages.

  10. Comparative evaluation of the effect of chlorhexidine and Aloe barbadensis Miller (Aloe vera on dentin stabilization using shear bond testing

    Directory of Open Access Journals (Sweden)

    Dakshita Joy Sinha

    2016-01-01

    Conclusion: CHX and A. barbadensis Miller, as pretreatment agents of acid demineralized dentin collagen, has no adverse effect on the immediate shear bond strength of a two-step etch and rinse adhesive to dentin.

  11. M. Deborrah Hyde, MD, MS: the second African-American female neurosurgeon.

    Science.gov (United States)

    McClelland, Shearwood

    2007-10-01

    A less-publicized consequence of the civil rights movement in the mid-20th century is the door of opportunity it provided for African-American women to become neurosurgeons, beginning in 1984 with Alexa I. Canady (University of Minnesota). Unfortunately, the exploits of a contemporary African-American woman neurosurgeon, M. Deborrah Hyde, have remained largely in obscurity. This report details the career and exploits of Hyde, one of the first women to receive neurosurgery training in Ohio. A comprehensive review of pertinent modern and historical records spanning the past century was performed. Born in 1949 in Laurel, MS, Hyde received her BS with honors from Tougaloo College in 1969 and her MS in biology at Cleveland State University. Despite being told in medical school that she was not qualified to compete with "better-prepared" nonminority students, Hyde received her MD from Case Western Reserve University School of Medicine in 1977, earning election into the Alpha Omega Alpha medical honor society. The next year, she began neurosurgery residency at Case Western under Dr. Robert A. Ratcheson and Dr. Robert F. Spetzler, finishing in 1982 as the program's first female graduate. In 1985, Hyde became the second African-American woman certified by the American Board of Neurological Surgery and in 1991 she established the Beacon of Hope Scholarship Foundation for underprivileged youth. She has subsequently continued a distinguished career in private practice, presently residing in West Hills, CA. Hyde's diligence, perseverance and commitment enabled her to overcome intense sexism and racism to train at Case Western, becoming the second African-American woman neurosurgeon and the third woman trained in Ohio (first and second of which were Carole Miller and Janet Bay). As the first woman to train under Ratcheson and Spetzler, her determination, excellence and generosity continue to inspire people of all races.

  12. MD5Hash加密算法在SQL Server2005中的应用%Application of MD5 Hash Encryption Algorithm in SQL Server 2005

    Institute of Scientific and Technical Information of China (English)

    李红日

    2011-01-01

    在对MD5算法进行简要描述的同时,对MD5算法的原理作深入分析.介绍在C创建MD5 Hash算法的函数,在SQL Server中应用MD5哈希算法,并且经过测试可以准确实现MD5 Hash加密算法.

  13. Find an Orthopaedic Foot and Ankle MD/DO

    Science.gov (United States)

    ... Content AOFAS / FootCareMD / Find a Surgeon Find an Orthopaedic Foot & Ankle Surgeon Page Content The Orthopaedic Distinction Who are Orthopaedic Foot & Ankle Surgeons? Orthopaedic foot and ankle surgeons ...

  14. Molecular Dynamics Simulations and XAFS (MD-XAFS)

    Energy Technology Data Exchange (ETDEWEB)

    Schenter, Gregory K.; Fulton, John L.

    2017-01-20

    MD-XAFS (Molecular Dynamics X-ray Adsorption Fine Structure) makes the connection between simulation techniques that generate an ensemble of molecular configurations and the direct signal observed from X-ray measurement.

  15. beta* leveling with telescopic ATS squeeze (MD 2410)

    CERN Document Server

    Wenninger, Jorg; Hostettler, Michi; Pojer, Mirko; Ponce, Laurette; Tydecks, Tobias; CERN. Geneva. ATS Department

    2017-01-01

    Luminosity leveling by beta* is the baseline operational scenario of HL-LHC, and this leveling technique may be used in 2018 or during run~3 depending on the beam parameters and beta* range. During this MD beta*leveling was commissioned successfully for the first time with the telescopic squeeze over the beta* range of 40 cm to 30 cm. A novel beta* leveling controls technique based on a modification of the LSA trim was also tested during the MD.

  16. Mattoso Câmara Jr. e a palavra prosódica Mattoso Câmara Jr. and the prosodic word

    Directory of Open Access Journals (Sweden)

    Leda Bisol

    2004-01-01

    Full Text Available Este artigo que se detém no conceito de palavra fonológica, fundamentando-se na Teoria Prosódica (Booij 1983, (Nespor & Vogel 1986, relembra Mattoso Câmara Jr., o primeiro entre nós a fazer específica diferença entre dois tipos de palavra, a que diz respeito aos morfemas, a que diz respeito à presença de um acento. Discutem-se a interação entre as duas unidades, a dimensão e as funções da palavra fonológica. Nestas simples linhas, nossa homenagem ao grande mestre de quem tivemos a felicidade de ser aluna.The subject of this paper is the phonological word and its interaction with the morphological word. The dimension, the domain and the functions of the phonological word are discussed following the principles of Prosodic Theory (Booij 1983, (Nespor & Vogel 1986. Câmara Jr's statements regarding Brazilian Portuguese are the basis of the considerations.

  17. Research of the Hash Algorithm Based on MD5%MD5散列算法的研究

    Institute of Scientific and Technical Information of China (English)

    姜学军; 曹烨

    2014-01-01

    借鉴了M.M.J.Stevens的碰撞思路,重新编写了MD5碰撞算法中的核心循环,主要提供一对MD5碰撞产生的过程以及碰撞的完成.通过实验统计分析,利用改进的MD5碰撞算法找到一对碰撞信息所用平均时间不多于60s,且该算法较之传统的MD5碰撞算法具有更好的可读性和可移植性.

  18. 基于MD5和Session的PHP安全防范%PHP security based on Session and MD5

    Institute of Scientific and Technical Information of China (English)

    何秉荣

    2014-01-01

    根据Session工作原理和MD5算法的特性,分析了PHP中Session欺骗与攻击手段,并较有针对性地在防范Session攻击的技术中结合MD5函数,从而提出了一个较为有效、实用的防范措施.

  19. An Analysis of the Tvergaard Parameters at Low Initial Stress Triaxiality for S235JR Steel

    Directory of Open Access Journals (Sweden)

    G. Kossakowski Paweł

    2015-01-01

    Full Text Available This paper discusses the influence of the Tvergaard parameters, qi, which are basic constants of the Gurson-Tvergaard-Needleman (GTN material model, on the numerically simulated load-carrying capacity of tensile elements made of S235JR steel. The elements were considered to be under static tension at low initial stress triaxiality σm/σe = 1/3. Two sets of the Tvergaard parameters qi were analyzed: those typical of structural steels and those dependent on material strength properties. The results showed that the Tvergaard parameters, qi, had influence on the load-carrying capacity of tensile elements at low initial stress triaxiality. They affected the strength curves and the changes in the void volume fractions determined for S235JR steel elements

  20. The Antiaircraft Journal. Volume 93, Number 6, November-December 1950

    Science.gov (United States)

    1950-12-01

    A.238th 11.11.11.Gun Bn., Camp Stewart, Ga. Childs, Claude F., Hq., 41st 11.11.11.Gun Bn., Ft. Dix, N.]. Christensen, Calvin H., 140 California St...H., Jr., Hq., 4th AAA AW Bn ..M, Fort Meade, Md. Miller, Leo G., Jr., C-398th AAA AW Bn.-SP, Camp Edwards, Mass. Morin , Remi F., D-398th AAA AW Bn

  1. Left to right, astronauts John H. Casper, mission commander, and Curtis L. Brown, Jr., pilot, get

    Science.gov (United States)

    1996-01-01

    STS-77 TRAINING VIEW --- Left to right, astronauts John H. Casper, mission commander, and Curtis L. Brown, Jr., pilot, get help with the final touches of suit donning during emergency bailout training for STS-77 crew members in the Johnson Space Centers (JSC) Weightless Environment Training Facility (WET-F). Casper and Brown will join four other astronauts for nine days aboard the Space Shuttle Endeavour next month.

  2. 最后消息:Bodies of JFK Jr.,Wife,Sister-in-Law Found

    Institute of Scientific and Technical Information of China (English)

    Tony; Munroe

    1999-01-01

    Searchers have found the bodies of John F. Kennedy Jr., his wife CarolynBessette Kennedy and her sister Lauren as well as a large piece of their crashedplane off the coast of Martha’s Vineyard, officials said Wednesday. Massachusetts Sen. Edward Kennedy and his two sons headed for the crashsite on a U. S. Coast Guard vessel after the bodies and wreckage (残骸) were

  3. Cicero's de legibus and Martin Luther King, Jr.’s Stride toward freedom

    Directory of Open Access Journals (Sweden)

    Boleslav s. Povšič

    1979-12-01

    Full Text Available He who reads carefully Cicero'sDe Legibus and Martin Luther King, Jr.'s Stride Toward Freedom is surprised to find, mutatis mutandis, on how many points these two great men agree. The historical circumstances are different, but the essential ideas are very similar. The purpose of this paper is to show on what precisely they agree and on what they differ.

  4. Community control of health services. Dr. Martin Luther King, Jr. Health Center's community management system.

    Science.gov (United States)

    Tichy, N M; Taylor, J I

    1976-01-01

    This article presents the case of Dr. Martin Luther King Jr. Health Center's unique community management system in which neighborhood workers have been developed to assume managerial responsibilities and are directing the Center. The Martin Luther King Center experience is instructive because the Center was able to achieve significant community control by focusing primarily on the internal dimension of control, namely, management, without experiencing destructive conflicts and the deterioration of health services.

  5. Chemical Analysis of a "Miller-Type" Complex Prebiotic Broth: Part I: Chemical Diversity, Oxygen and Nitrogen Based Polymers.

    Science.gov (United States)

    Wollrab, Eva; Scherer, Sabrina; Aubriet, Frédéric; Carré, Vincent; Carlomagno, Teresa; Codutti, Luca; Ott, Albrecht

    2016-06-01

    In a famous experiment Stanley Miller showed that a large number of organic substances can emerge from sparking a mixture of methane, ammonia and hydrogen in the presence of water (Miller, Science 117:528-529, 1953). Among these substances Miller identified different amino acids, and he concluded that prebiotic events may well have produced many of Life's molecular building blocks. There have been many variants of the original experiment since, including different gas mixtures (Miller, J Am Chem Soc 77:2351-2361, 1955; Oró Nature 197:862-867, 1963; Schlesinger and Miller, J Mol Evol 19:376-382, 1983; Miyakawa et al., Proc Natl Acad Sci 99:14,628-14,631, 2002). Recently some of Miller's remaining original samples were analyzed with modern equipment (Johnson et al. Science 322:404-404, 2008; Parker et al. Proc Natl Acad Sci 108:5526-5531, 2011) and a total of 23 racemic amino acids were identified. To give an overview of the chemical variety of a possible prebiotic broth, here we analyze a "Miller type" experiment using state of the art mass spectrometry and NMR spectroscopy. We identify substances of a wide range of saturation, which can be hydrophilic, hydrophobic or amphiphilic in nature. Often the molecules contain heteroatoms, with amines and amides being prominent classes of molecule. In some samples we detect ethylene glycol based polymers. Their formation in water requires the presence of a catalyst. Contrary to expectations, we cannot identify any preferred reaction product. The capacity to spontaneously produce this extremely high degree of molecular variety in a very simple experiment is a remarkable feature of organic chemistry and possibly prerequisite for Life to emerge. It remains a future task to uncover how dedicated, organized chemical reaction pathways may have arisen from this degree of complexity.

  6. Chemical Analysis of a "Miller-Type" Complex Prebiotic Broth. Part I: Chemical Diversity, Oxygen and Nitrogen Based Polymers

    Science.gov (United States)

    Wollrab, Eva; Scherer, Sabrina; Aubriet, Frédéric; Carré, Vincent; Carlomagno, Teresa; Codutti, Luca; Ott, Albrecht

    2016-06-01

    In a famous experiment Stanley Miller showed that a large number of organic substances can emerge from sparking a mixture of methane, ammonia and hydrogen in the presence of water (Miller, Science 117:528-529, 1953). Among these substances Miller identified different amino acids, and he concluded that prebiotic events may well have produced many of Life's molecular building blocks. There have been many variants of the original experiment since, including different gas mixtures (Miller, J Am Chem Soc 77:2351-2361, 1955; Oró Nature 197:862-867, 1963; Schlesinger and Miller, J Mol Evol 19:376-382, 1983; Miyakawa et al., Proc Natl Acad Sci 99:14,628-14,631, 2002). Recently some of Miller's remaining original samples were analyzed with modern equipment (Johnson et al. Science 322:404-404, 2008; Parker et al. Proc Natl Acad Sci 108:5526-5531, 2011) and a total of 23 racemic amino acids were identified. To give an overview of the chemical variety of a possible prebiotic broth, here we analyze a "Miller type" experiment using state of the art mass spectrometry and NMR spectroscopy. We identify substances of a wide range of saturation, which can be hydrophilic, hydrophobic or amphiphilic in nature. Often the molecules contain heteroatoms, with amines and amides being prominent classes of molecule. In some samples we detect ethylene glycol based polymers. Their formation in water requires the presence of a catalyst. Contrary to expectations, we cannot identify any preferred reaction product. The capacity to spontaneously produce this extremely high degree of molecular variety in a very simple experiment is a remarkable feature of organic chemistry and possibly prerequisite for Life to emerge. It remains a future task to uncover how dedicated, organized chemical reaction pathways may have arisen from this degree of complexity.

  7. Comparison of the clinical applicability of Miller's classification system to Kumar and Masamatti's classification system of gingival recession

    Science.gov (United States)

    Kumar, Ashish; Gupta, Geeti; Puri, Komal; Bansal, Mansi; Jain, Deept; Khatri, Manish; Masamatti, Sujata Surendra

    2015-01-01

    Background: The aims of the present study were to (i) Find the percentage of recession cases that could be classified by application of Miller's and/or Kumar and Masamatti's classification of gingival recession, and (ii) compare the percentage of clinical applicability of Miller's criteria and Kumar and Masamatti's criteria to the total recessions present. Materials and Methods: A total of 104 patients (1089 recession cases) were included in the study wherein they were classified using both Miller's and Kumar and Masamatti's classification systems of gingival recession. Percentage comparison of the application of both classification systems was done. Results: Data analysis showed that though all the cases of the recession were classified by Kumar and Masamatti's classification, only 34.61% cases were classified by Miller's classification. 19.10% cases were completely (having only labial/buccal recession) classified. In 15.51% (out of 34.61%) cases, only buccal recession was classified according to Miller's criteria and included in this category, although these cases had both buccal and lingual/palatal recessions. Furthermore, 29.75% cases of recession with interdental loss and marginal tissue loss coronal to mucogingival junction (MGJ) remained uncategorized by Miller's classification; categorization of palatal/lingual recession was possible with Kumar and Masamatti's classification. Conclusion: The elaborative evaluation of both buccal and palatal/lingual recession by the Kumar and Masamatti's classification system can be used to overcome the limitations of Miller's classification system, especially the cases with interdental loss and having marginal tissue loss coronal to MGJ. PMID:26644724

  8. Three-Year MD Programs: Perspectives From the Consortium of Accelerated Medical Pathway Programs (CAMPP).

    Science.gov (United States)

    Cangiarella, Joan; Fancher, Tonya; Jones, Betsy; Dodson, Lisa; Leong, Shou Ling; Hunsaker, Matthew; Pallay, Robert; Whyte, Robert; Holthouser, Amy; Abramson, Steven B

    2017-04-01

    In the last decade, there has been renewed interest in three-year MD pathway programs. In 2015, with support from the Josiah Macy Jr., Foundation, eight North American medical schools with three-year accelerated medical pathway programs formed the Consortium of Accelerated Medical Pathway Programs (CAMPP). The schools are two campuses of the Medical College of Wisconsin; McMaster University Michael G. DeGroote School of Medicine; Mercer University School of Medicine; New York University School of Medicine; Penn State College of Medicine; Texas Tech University Health Sciences Center School of Medicine; University of California, Davis School of Medicine; and University of Louisville School of Medicine. These programs vary in size and medical specialty focus but all include the reduction of student debt from savings in tuition costs. Each school's mission to create a three-year pathway program differs; common themes include the ability to train physicians to practice in underserved areas or to allow students for whom the choice of specialty is known to progress more quickly. Compared with McMaster, these programs are small, but most capitalize on training and assessing competency across the undergraduate medical education-graduate medical education continuum and include conditional acceptance into an affiliated residency program. This article includes an overview of each CAMPP school with attention to admissions, curriculum, financial support, and regulatory challenges associated with the design of an accelerated pathway program. These programs are relatively new, with a small number of graduates; this article outlines opportunities and challenges for schools considering the development of accelerated programs.

  9. Cummins MD & HD Accessory Hybridization CRADA -Annual Report FY15

    Energy Technology Data Exchange (ETDEWEB)

    Deter, Dean D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-10-01

    There are many areas of MD and HD vehicles that can be improved by new technologies and optimized control strategies. Component optimization and idle reduction need to be addressed, this is best done by a two part approach that includes selecting the best component technology, and/or architecture, and optimized controls that are vehicle focused. While this is a common focus in the light duty industry it has been gaining momentum in the MD and HD market as the market gets more competitive and the regulations become more stringent. When looking into systems optimization and idle reduction technologies, affected vehicle systems must first be considered, and if possible included in the new architecture to get the most benefit out of these new capabilities. Typically, when looking into idle reduction or component optimization for MD/HD, the vehicle s accessories become a prime candidate for electrification or hybridization. While this has already been studied on light duty vehicles (especially on hybrids and electric vehicles) it has not made any head way or market penetration in most MD and HD applications. If hybrids and electric MD and HD vehicles begin to break into the market this would be a necessary step into the ability to make those vehicles successful by allowing for independent, optimized operation separate from the engine.

  10. Jules Verne Voyager, Jr: An Interactive Map Tool for Teaching Plate Tectonics

    Science.gov (United States)

    Hamburger, M. W.; Meertens, C. M.

    2010-12-01

    We present an interactive, web-based map utility that can make new geological and geophysical results accessible to a large number and variety of users. The tool provides a user-friendly interface that allows users to access a variety of maps, satellite images, and geophysical data at a range of spatial scales. The map tool, dubbed 'Jules Verne Voyager, Jr.', allows users to interactively create maps of a variety of study areas around the world. The utility was developed in collaboration with the UNAVCO Consortium for study of global-scale tectonic processes. Users can choose from a variety of base maps (including "Face of the Earth" and "Earth at Night" satellite imagery mosaics, global topography, geoid, sea-floor age, strain rate and seismic hazard maps, and others), add a number of geographic and geophysical overlays (coastlines, political boundaries, rivers and lakes, earthquake and volcano locations, stress axes, etc.), and then superimpose both observed and model velocity vectors representing a compilation of 2933 GPS geodetic measurements from around the world. A remarkable characteristic of the geodetic compilation is that users can select from some 21 plates' frames of reference, allowing a visual representation of both 'absolute' plate motion (in a no-net rotation reference frame) and relative motion along all of the world's plate boundaries. The tool allows users to zoom among at least three map scales. The map tool can be viewed at http://jules.unavco.org/VoyagerJr/Earth. A more detailed version of the map utility, developed in conjunction with the EarthScope initiative, focuses on North America geodynamics, and provides more detailed geophysical and geographic information for the United States, Canada, and Mexico. The ‘EarthScope Voyager’ can be accessed at http://jules.unavco.org/VoyagerJr/EarthScope. Because the system uses pre-constructed gif images and overlays, the system can rapidly create and display maps to a large number of users

  11. MANEJO DE CORTE DAS FOLHAS DE Copernicia prunifera (Miller) H. E. Moore NO PIAUÍ

    OpenAIRE

    CLEMILTON DA SILVA FERREIRA; JOSÉ AIRTON RODRIGUES NUNES; REGINA LUCIA FERREIRA GOMES

    2013-01-01

    The carnauba (Copernicia prunifera (Miller) HE Moore) is a native fruit species to the north- east of Brazil and its exploration is based mainly on the extract of wax powder from leaves. The objective of this study was to evaluate the effect of different management strategies of cutting leaves, developmental stages and leaf age on leaf traits and physical-chemical attributes of carnauba wax in a natural population of carnauba palm located at the Cajazeira Farm, municipality of União, Piauí st...

  12. An evaluation of the biological and toxicological properties of Aloe barbadensis (miller), Aloe vera.

    Science.gov (United States)

    Boudreau, Mary D; Beland, Frederick A

    2006-04-01

    Aloe barbadensis (Miller), Aloe vera, has a long history of use as a topical and oral therapeutic. The plant is the source of two products, gel and latex, which are obtained from its fleshy leaves. Aloe vera products contain multiple constituents with potential biological and toxicological activities, yet the active components elude definition. Ingestion of Aloe vera is associated with diarrhea, electrolyte imbalance, kidney dysfunction, and conventional drug interactions; episodes of contact dermatitis, erythema, and phototoxicity have been reported from topical applications. This review examines the botany, physical and chemical properties, and biological activities of the Aloe vera plant.

  13. Şeftali (Persica vulgaris Miller yaprak ekstraktının antibakteriyel etkisi

    Directory of Open Access Journals (Sweden)

    Hülya Özpınar

    2013-06-01

    Full Text Available Amaç. Çalışmamızda şeftali (Persica vulgaris Miller yaprak ekstraktının antibakteriyel etkisini tespit etmek amaçlanmıştır. Yöntem. Erzincan Bahçe Bitkileri Araştırma Enstitüsü Gen Bahçesi’nde bulunan Cardinal çeşidi 7 adet şeftali (Persica vulgaris Miller ağacı yaprağı methanol ekstraktı bu amaçla kullanılmıştır. Antibakteriyel etkisinin araştırılmasında cut plug yöntemi kullanılırken Minimum İnhibisyon Konsantrasyonu (MİK, mikrodilüsyon yöntemi ile belirlenmiştir. Bulgular. Bu çalışmada şeftali (Persica vulgaris Miller yaprak ektraktının Staphylococcus aureus, Staphylococcus aureus (MRSA’a karşı antibakteriyel etkisi belirlenemezken, Escherichia coli, Escherichia coli O:157 H:7, Proteus mirabilis, Proteus vulgaris, Salmonella enteritidis, Salmonella typhimurium, Streptococcus pyogenes, Enterococcus faecalis, Staphylococcus epidermidis, Klebsiella pneumoniae, Listeria monocytogenes, Micrococcus luteus ,Pseudomonas aeruginosa, Bacillus cereus, Bacillus subtilis, Yersinia enterocolitica bakterilerine karşı ise antibakteriyel etki tespit edilmiştir. En düşük Minimum İnhibisyon Konsantrasyonu Pseudomonas aeruginosa ve Yersinia enterocolitica’da tespit edilirken (0,01 mg/mL, en yüksek konsantrasyon Bacillus subtilis, Escherichia coli, Escherichia coli O:157 H:7, Salmonella enteritidis, Salmonella typhimurium, Staphylococcus epidermidis, Streptococcus pyogenes’de görülmüştür (10 mg/mL. Sonuç. Çalışmamız sonucunda şeftali (Persica vulgaris Miller yaprak ekstraktının antibakteriyel etki spektrumu invitro olarak tespit edilmiş olup bu tür bitkilerden yola çıkılarak yeni antibakteriyel ajanların oluşum sürecinin başlatılabileceği düşünülmektedir.

  14. Why there is no supernatural morality: response to Miller's opening statement.

    Science.gov (United States)

    Shermer, Michael

    2016-11-01

    If one is going to argue that objective morality depends on an Archimedean point outside the natural world, then it would seem to imply that this source is necessarily supernatural. Thus, Christian Miller begins by defining precisely who he thinks this supernatural moral law giver is: the omniscient, omnipotent, and omnibenevolent creator of the universe who is still actively involved with human affairs-Elohim, Jehovah, Yahweh, or Allah-aka God. Already I'm skeptical. © 2016 New York Academy of Sciences.

  15. The Concept of Blindness in Sophocles' King Oedipus and Arthur Miller's Death of a Salesman

    OpenAIRE

    Md. Ziaul Haque; Fahmida Kabir Chowdhury

    2013-01-01

    In King Oedipus (429 B.C.E) by Sophocles and Death of a Salesman (1949 A.D) by Arthur Miller, the central characters Oedipus and Willy Loman take extreme pride in their professions; their pride blinds them from seeing the reality of their circumstances, and it eventually brings their ruin. At he same time, the other characters also display their figurative blindness in both the tragedies. However, it is demonstrated that the protagonists do not succeed in executing their responsibilities as l...

  16. L'experiment de Miller-Urey s'instal·la a la UAB

    OpenAIRE

    Universitat Autònoma de Barcelona. Àrea de Comunicació i de Promoció

    2007-01-01

    Dins de l'Any de l'Evolució, a la UAB, les Facultats de Ciències i de Biociències van organitzar, el 28 de febrer, la jornada "Evolució Prebiòtica". La jornada va incloure diverses xerrades i la inauguració de la reproducció de l'aparell de Miller-Urey que s'ha instal·lat, de manera permanent, a les Facultats de Ciències i de Biociències.

  17. Lee Miller à travers la Roumanie, l’appareil photo à la main (1946

    Directory of Open Access Journals (Sweden)

    Adrian-Silvan Ionescu

    2012-01-01

    Full Text Available A former model and fashion photographer turned war photographer, Lee Miller visited Romania twice, in 1938 and 1946 respectively. After her second visit she published her impressions and pictures, under the title of Roumania, in Vogue magazine. Besides the published material there are her manuscripts from The Lee Miller Achives at Farley Farm House, East Sussex, England, on which this paper is based. She crossed the border coming from Hungary in early February 1946. Heading for Sibiu her car, a Chevrolet Sedan, slipping on the ice-covered road, stopped on a snowbank far off in the ditch. While looking for help in the nearby village she and her companions left the car unguarded to discover it plundered of everything, wheels included.On a Sunday afternoon she had the privilege of being received by King Mihai I and Queen Mother Elena with whom she talked exstensively. She also took magnificent pictures with the Royal Family in the imposing Peleş Castle. At Sinaia, „the summer capital of Roumania” she had also the opportunity to portray Dinu Brătianu and Iuliu Maniu, the two elderly statesmen. Maniu was surrounded by friends and party members, among whom was young Corneliu Coposu, his private secretary.Moving to Bucharest, she met old friends such as Harri Brauner and his wife, Lena Constante, with whom she wandered through the country eight years ago. Lena and Elena Pătrășcanu, wife of Lucrețiu Pătrășcanu, Minister of Justice, have started a successful marionette theatre where Lee took nice pictures. Other were taken on the streets, with peasants, street vendors and their customers. Harri took her to a bistro where they met Maria Lătărețu, the celebrating folk singer whom Brauner recorded many times. They enjoyed her songs. Suffering from fibrositis, Lee Miller undertook a peculiar treatment in a gypsy village where the inhabitants were dancing bears trainers. She was massaged by a bear weighing about 300 pounds while Brauner took

  18. CHIRIMOYA (Annona cherimola Miller), FRUTAL TROPICAL Y SUB-TROPICAL DE VALORES PROMISORIOS

    OpenAIRE

    María Esther González Vega

    2013-01-01

    Los frutos de anonáceas, entre ellos la chirimoya, presentan altas cualidades organolépticas, digestivas y nutritivas, además, como especie, la Annona cherimola Miller también es apreciada por sus propiedades medicinales e industriales tanto en el mercado nacional como internacional. Sin embargo, aún existe desconocimiento sobre sus características y potencialidades como planta cultivada. En el presente trabajo se exponen informaciones sobre esta especie y se discute la importancia de la expa...

  19. J.R. Simplot: Burner Upgrade Project Improves Performance and Saves Energy at a Large Food Processing Plant

    Energy Technology Data Exchange (ETDEWEB)

    2005-09-01

    This DOE Industrial Program case study describes how the J.R. Simplot Company saved energy and money by increasing the efficiency of the steam system in its potato processing plant in Caldwell, Idaho.

  20. J.R. Simplot: Burner Upgrade Project Improves Performance and Saves Energy at a Large Food Processing Plant (Steam)

    Energy Technology Data Exchange (ETDEWEB)

    None

    2005-09-01

    This DOE Industrial Program case study describes how the J.R. Simplot Company saved energy and money by increasing the efficiency of the steam system in its potato processing plant in Caldwell, Idaho.

  1. J.R. Simplot: Burner Upgrade Project Improves Performance and Saves Energy at a Large Food Processing Plant

    Energy Technology Data Exchange (ETDEWEB)

    2005-09-01

    This DOE Industrial Program case study describes how the J.R. Simplot Company saved energy and money by increasing the efficiency of the steam system in its potato processing plant in Caldwell, Idaho.

  2. J.R. Simplot: Burner Upgrade Project Improves Performance and Saves Energy at a Large Food Processing Plant (Steam)

    Energy Technology Data Exchange (ETDEWEB)

    None

    2005-09-01

    This DOE Industrial Program case study describes how the J.R. Simplot Company saved energy and money by increasing the efficiency of the steam system in its potato processing plant in Caldwell, Idaho.

  3. CoMD Implementation Suite in Emerging Programming Models

    Energy Technology Data Exchange (ETDEWEB)

    2014-09-23

    CoMD-Em is a software implementation suite of the CoMD [4] proxy app using different emerging programming models. It is intended to analyze the features and capabilities of novel programming models that could help ensure code and performance portability and scalability across heterogeneous platforms while improving programmer productivity. Another goal is to provide the authors and venders with some meaningful feedback regarding the capabilities and limitations of their models. The actual application is a classical molecular dynamics (MD) simulation using either the Lennard-Jones method (LJ) or the embedded atom method (EAM) for primary particle interaction. The code can be extended to support alternate interaction models. The code is expected ro run on a wide class of heterogeneous hardware configurations like shard/distributed/hybrid memory, GPU's and any other platform supported by the underlying programming model.

  4. 基于Caputo导数的Miller-Ross序列导数微分方程的稳定性分析%Stability Analysis of Fractional Differential Equations with Miller-Ross Sequential Derivative in Caputo Sense

    Institute of Scientific and Technical Information of China (English)

    钱德亮; 李常品

    2012-01-01

    讨论了基于Caputo导数的Miller-Ross序列导数的分数阶微分方程的稳定性.根据Laplace变换,得到分数阶微分方程的解;应用Mittag-Leffler函数的渐近展开,讨论了方程的稳定性.分两部分:齐次方程与非齐次方程.%Stability analysis of the linear fractional differential systems with Caputo derivar tive has been well-studied, the differential system with Miller-Ross sequential derivative in Caputo sense, however, has not been investigated yet. In this paper, by using the Laplace transform and the asymptotical expansion of the Mittag-Leffler function, we derive the stability criteria of the fractional differential systems with Miller-Ross sequential fractional derivative in Caputo sense, where two cases are included: the homogenous case and the non-homogenous one.

  5. 基于C#的MD5加密算法的应用%Application of the MD5 algorithm based on C#

    Institute of Scientific and Technical Information of China (English)

    林宗朝

    2011-01-01

    介绍了WEB SYSTEM中的密钥安全性能。主要讨论了WEB SYSTEM中MD5加密算法,包含客户password安全性分析、MD5加密算法概述、基于C#的MD5加密应用介绍,以及IT SYSTEM中MD5算法的应用与IMPROVEMENT等问题。%The key safety properties of the WEB system is described,and the.MD5 encryption algorithm is discussed mainly including the user password security analysis,MD5 encryption algorithm summary,MD5 encryption applications based on the C# and the improvement of MD5 algorithm.

  6. BayesMD: flexible biological modeling for motif discovery

    DEFF Research Database (Denmark)

    Tang, Man-Hung Eric; Krogh, Anders; Winther, Ole

    2008-01-01

    We present BayesMD, a Bayesian Motif Discovery model with several new features. Three different types of biological a priori knowledge are built into the framework in a modular fashion. A mixture of Dirichlets is used as prior over nucleotide probabilities in binding sites. It is trained on trans......We present BayesMD, a Bayesian Motif Discovery model with several new features. Three different types of biological a priori knowledge are built into the framework in a modular fashion. A mixture of Dirichlets is used as prior over nucleotide probabilities in binding sites. It is trained...

  7. Restructuring the syllabus for MD Pharmacology: Retrospection of bioassay

    Directory of Open Access Journals (Sweden)

    Sarita Mulkalwar

    2014-01-01

    Full Text Available Introduction: Career prospects in Pharmacology are witnessing a sea change due to fast and unanticipated development in the field of clinical research. Numerous openings exist now in academia, pharmaceutical industry, Clinical Research Organizations (CRO or as regulatory consultants, experimental pharmacologists, etc. In short, there are various options to choose from, depending on one′s interest. It′s high time we ponder now over the training programme for post-graduate students in Pharmacology. It needs to be revised keeping in mind the job prospects & uniqueness of the MD Pharmacology degree. Aim: To take suggestions of experienced pharmacologists on the present syllabus for MD Pharmacology and their opinion on continuation of Bioassay experiment which is currently an important part of it . Materials and Methods: A structured questionnaire was given to 30 experienced pharmacologists to seek their opinion on MD Pharmacology syllabus & continuation of Bioassay as a part of MD practical. Results: Out of 30 participants, 29 (96.6% did not use their knowledge of Bioassay during their 10 years of post MD career, whether in pharmaceutical industry or in academics. Only 5 of them (16.6% feel that experiment on bioassay should be continued in the current state. 76.7% of them wish it to be modified to a Dose Response Curve ( DRC . 6.71% feel that it should be totally scrapped. All the participants feel the need of revising current MD Pharmacology syllabus. Current syllabus is inclined more towards preparing good academicians but it lacks the proper training for creating good clinical research professionals. Medical writing, writing necessary documents for clinical trials including regulatory documents, writing an article for medical journals, marketing communication, product monograph and patient information of a clinical trial could be incorporated. They should be aware of the regulatory requirements for conducting studies on investigational drugs

  8. BI MD Studies on June 29th 2011

    CERN Document Server

    Belohrad, D; Bravin, E; Calvo, E; Dehning, B; Emery, J; Favier, M; Gras, JJ; Guerrero, A; Jeff, A; Lefevre, T; Rabiller, A; Roncarolo, F; Sapinski, M; Soby, L; Steinhagen, R

    2011-01-01

    This note contains the preliminary results of the LHC MD that took place on 29-June-2011 (from 10 p.m. to 07 a.m.), dedicated to study Beam Current Monitors (BCT), Wire Scaners (WS), Synchrotron Radiation (BSRT), Beam Position (BPM), Wall Current (WCM) and Beam Gas Ionization (BGI) monitors. The MD aimed at performing different studies on the individual monitors. At the same time, it was possible to perform calibration studies with the Abort Gap (AGM) and Longitudinal Density (LDM) monitors that share the extracted light with the BSRT. Additionally some observations about the beam stability and emittance dependence on the chromaticity were performed.

  9. I teoremi di Modigliani-Miller: una pietra miliare della finanza (The theorems of Modigliani-Miller: a cornerstone of finance

    Directory of Open Access Journals (Sweden)

    Marco Pagano

    2012-04-01

    Full Text Available The theorems of Modigliani and Miller (MM is a cornerstone of finance for two reasons.The first is substantial and is derived from the nature of "propositions irrelevant": they identify a case in which the financial structure and dividend policy will not affect the value of firms, and in doing so give us a clear point of reference to understand instead what circumstances these decisions affect the value of firms, and why. In fact, the whole subsequent evolution of corporate finance has explored the consequences of removing the assumptions of MM. The second reason for the importance of the fundamental theorems of MM is methodological: they have been demonstrated with a reasoning based arbitrage, which has set a precedent not only in the area of ​​corporate finance but also in that of the determination of prices of financial securities. I teoremi di Modigliani e Miller (MM sono una pietra miliare della finanza per due ragioni. La prima è sostanziale e deriva dalla loro natura di “proposizioni di irrilevanza”: essi individuano un caso in cui la struttura finanziaria e la politica dei dividendi non influiscono sul valore delle imprese, e così facendo ci danno un chiaro punto di riferimento per capire in quali circostanze invece queste decisioni influiscono sul valore delle imprese, e perché. In effetti, l’intera evoluzione successiva della finanza aziendale ha esplorato le conseguenze della rimozione delle ipotesi di MM. La seconda ragione dell’importanza fondamentale dei teoremi di MM è di tipo metodologico: essi sono stati dimostrati con un ragionamento basato sull’arbitraggio, il che ha stabilito un precedente non solo nel campo della finanza aziendale ma anche e soprattutto in quello della determinazione dei prezzi dei titoli finanziari.  JEL Codes: G32, G35Keywords: struttura finanziaria; politica dei dividendi; valore delle imprese

  10. ZACK SNYDER, FRANK MILLER AND HERODOTUS: THREE TAKES ON THE 300 SPARTANS

    Directory of Open Access Journals (Sweden)

    G.N. Murray

    2012-03-01

    Full Text Available The heroic defence of the Greeks at the battle of Thermopylae in 480 BC, in particularly the 300 Spartans who stood to the last man against the much larger Persian force, prompted comic book writer and illustrator Frank Miller to retell this story from a purely Spartan perspective. This version was retold once again when director Zack Snyder created a filmed version of the graphic novel named 300. Despite the film’s achievements at the box office, it was attacked for being, amongst others, historically incorrect and ideologically biased. In the graphic novel Frank Miller tells the tale of the battle at Thermopylae through the eyes of a Spartan warrior who bore the responsibility of spreading their tale so that the Spartans’ sacrifice might compel other Greek city-states to stand together against the Persians. Therefore the graphic novel and especially the film are drenched with Spartan superiority and Persian inferiority. Despite the inaccuracies and ideological bias, there are a few moments in the graphic novel and film that are notably historically correct.

  11. Pornografia e transgressão na obra literária de Henry Miller

    Directory of Open Access Journals (Sweden)

    Raquel Catunda Pereira

    2016-07-01

    Full Text Available The North American writer Henry Miller was marginalized by literary critics since the first publications of his works in the 40s. Accused of being a pornographic text, the book Tropic of Cancer (1934 was forbidden in many countries. This article aims to analyze the obscene in Henry Miller’s work to prove that, beyond the erotic intention, Miller’s books are an expression of freedom and rejection of moral standards. In order to achieve our goal, we will use as theoretical basis the articles Criticismo e sexualidade: uma leitura de Tropico of Capricorn de Henry Miller, by Flávia Andréa Rodrigues Benfatt, and Literatura marginal americana: do épico confessional ao niilismo erótico, by Lainister de Oliveira. The texts mentioned above grant us the argumentation necessary to the analysis of pornographic discourse in Henry Miller’s literary works as the author’s aesthetics choice of taking himself as a transgressor in a decadent society.

  12. Compensation of the detector capacitance presented to charge-sensitive preamplifiers using the Miller effect

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Inyong, E-mail: iykwon@umich.edu [University of Michigan, Ann Arbor, MI (United States); Kang, Taehoon, E-mail: thnkang@umich.edu [University of Michigan, Ann Arbor, MI (United States); Wells, Byron T., E-mail: wells@galtresearch.com [Galt LLC, Ypsilanti, MI (United States); D’Aries, Lawrence J., E-mail: lawrence.j.daries.civ@mail.mil [Picatinny Arsenal, Rockaway Township, NJ (United States); Hammig, Mark D., E-mail: hammig@umich.edu [University of Michigan, Ann Arbor, MI (United States)

    2015-06-01

    This paper describes an integrated circuit design for a modified charge-sensitive amplifier (CSA) that compensates for the effect of capacitance presented by nuclear radiation detectors and other sensors. For applications that require large area semiconductor detectors or for those semiconductor sensors derived from high permittivity materials such as PbSe, the detector capacitance can degrade the system gain and bandwidth of a front-end preamplifier, resulting in extended rise times and attenuated output voltage signals during pulse formation. In order to suppress the effect of sensor capacitance, we applied a bootstrap technique into a traditional CSA. The technique exploits the Miller effect by reducing the effective voltage difference between the two sides of a radiation detector which minimizes the capacitance presented to the differential common-source amplifier. This new configuration is successfully designed to produce effective gain even at high detector capacitance. The entire circuit, including a core CSA with feedback components and a bootstrap amplifier, are implemented in a 0.18 μm CMOS process with a 3.3 V supply voltage. - Highlights: • A modified CSA was implemented for detector capacitance compensation. • Increasing detector capacitance degrades gain and rise time. • A bootstrap amplifier exploiting the Miller effect is described. • It allows using large area radiation sensors for high radiation-interaction rates. • Intensive noise analyses show that SNR is much better with the technique.

  13. Teorema Modigliani-Miller, imperfetta informazione e meccanismo di trasmissione della politica monetaria

    Directory of Open Access Journals (Sweden)

    G. BERTOCCO

    2013-10-01

    Full Text Available The work first aims to show that the Modigliani-Miller theorem can not constitute the theoretical foundation of traditional analysis. It then analyses the consequences of the presence of imperfect information on the characteristics of the transmission mechanism of monetary policy. It is observed that the dependence on commercial bank credit is not a sufficient condition for operating a transmission mechanism based on the control of the amount of credit that is different from the traditional mechanism. If the banking system could isolate the supply of credit through central bank decisions, the effects of monetary policy would be transmitted through interest rates, as established traditional analysis. The author shows that the characteristics of the transmission mechanism of monetary policy do not depend only on the presence of imperfect information, but also on the assumptions regarding the determination of the supply of credit.  JEL Codes: E52, G14Keywords: Modigliani-Miller theorem, monetary policy, transition mechanism, credit

  14. Improved Collision Attack on Hash Function MD5

    Institute of Scientific and Technical Information of China (English)

    Jie Liang; Xue-Jia Lai

    2007-01-01

    In this paper, we present a fast attack algorithm to find two-block collision of hash function MD5.The algorithm is based on the two-block collision differential path of MD5 that was presented by Wang et al.In the Conference EUROCRYPT 2005.We found that the derived conditions for the desired collision differential path were not sufficient to guarantee the path to hold and that some conditions could be modified to enlarge the collision set.By using technique of small range searching and omitting the computing steps to check the characteristics in the attack algorithm, we can speed up the attack of MD5 efficiently.Compared with the Advanced Message Modification technique presented by Wang et al.,the small range searching technique can correct 4 more conditions for the first iteration differential and 3 more conditions for the second iteration differential, thus improving the probability and the complexity to find collisions.The whole attack on the MD5 can be accomplished within 5 hours using a PC with Pentium4 1.70GHz CPU.

  15. Biomolecular recognition mechanisms studied by NMR spectroscopy and MD simulations

    NARCIS (Netherlands)

    Hsu, Shang-Te Danny

    2004-01-01

    This thesis describes the use of solution Nuclear Magnetic Resonance (NMR) spectroscopy and Molecular Dynamics (MD) simulations to study the mechanism of biomolecular recognition with two model systems: i) lipid II-binding lantibiotics (lanthionine-containing antibiotics) and ii) the human immunodef

  16. 77 FR 12476 - Drawbridge Operation Regulation; Curtis Creek, Baltimore, MD

    Science.gov (United States)

    2012-03-01

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 RIN 1625-AA09 Drawbridge Operation Regulation; Curtis Creek, Baltimore..., across Curtis Creek, mile 1.0, at Baltimore, MD. This deviation allows the bridge to operate on...

  17. 75 FR 54069 - Drawbridge Operation Regulations; Curtis Creek, Baltimore, MD

    Science.gov (United States)

    2010-09-03

    ... (75 FR 30747-30750). The rulemaking concerned eliminating the need for a bridge tender by allowing the... SECURITY Coast Guard 33 CFR Part 117 RIN 1625--AA09 Drawbridge Operation Regulations; Curtis Creek... Avenue Bridge, at mile 0.9, across Curtis Creek at Baltimore, MD. The requested change would have...

  18. 75 FR 1705 - Drawbridge Operation Regulations; Curtis Creek, Baltimore, MD

    Science.gov (United States)

    2010-01-13

    ... SECURITY Coast Guard 33 CFR Part 117 RIN 1625-AA09 Drawbridge Operation Regulations; Curtis Creek... operation of the I695 Bridge across Curtis Creek, mile 0.9, at Baltimore, MD. The deviation is necessary to... section of Curtis Creek and the bridge will not be able to open in the event of an emergency. Coast...

  19. 75 FR 50707 - Drawbridge Operation Regulation; Curtis Creek, Baltimore, MD

    Science.gov (United States)

    2010-08-17

    ... SECURITY Coast Guard 33 CFR Part 117 RIN 1625-AA09 Drawbridge Operation Regulation; Curtis Creek, Baltimore... operation of the Pennington Avenue Bridge, across Curtis Creek, mile 0.9, at Baltimore, MD. This deviation... vessels bound for the Coast Guard Yard at Curtis Bay, as well as a significant amount of commercial...

  20. QM/MM-MD simulations of conjugated polyelectrolytes

    DEFF Research Database (Denmark)

    Sjöqvist, Jonas; Linares, Mathieu; Mikkelsen, Kurt Valentin

    2014-01-01

    description of the solvent in its electronic ground state as well as the chromophore in its electronic ground and excited states, (ii) a conformational sampling by means of classical molecular dynamics (MD) in the respective electronic states, and (iii) spectral response calculations by means of the quantum...

  1. 77 FR 73967 - Drawbridge Operation Regulation; Bear Creek, Dundalk, MD

    Science.gov (United States)

    2012-12-12

    ... Regulation; Bear Creek, Dundalk, MD'' in the Federal Register (77 FR 5201). The rulemaking concerned would... proposed rulemaking the bridge owner displayed on the Wise Avenue Bridge signage that stated a 48-hour advance notice was required to open the draw bridge. This signage portrayed improper...

  2. 78 FR 65180 - Airworthiness Directives; MD Helicopters, Inc., Helicopters

    Science.gov (United States)

    2013-10-31

    ... condition, vibration, loss of tail rotor pitch control, and loss of directional control of the helicopter...-047-AD; Amendment 39-17606; AD 2013-19-24] RIN 2120-AA64 Airworthiness Directives; MD Helicopters, Inc., Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We...

  3. 78 FR 27867 - Airworthiness Directives; MD Helicopters Inc. Helicopters

    Science.gov (United States)

    2013-05-13

    ..., leading to vibration, loss of tail rotor pitch control, and subsequent loss of tail rotor and helicopter... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; MD Helicopters Inc. Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking...

  4. A designed TLR4/MD-2 complex to capture LPS.

    Science.gov (United States)

    Brandl, Katharina; Glück, Thomas; Hartmann, Pia; Salzberger, Bernd; Falk, Werner

    2005-01-01

    The family of Toll-like receptors (TLRs) is involved in the defense of an organism to microbial attack. TLR4-induced signaling is involved in infectious diseases, chronic inflammatory diseases and sepsis; therefore, we aimed at modulating TLR4-signaling via ligand-binding soluble receptors. Because recognition of microbial structures shows some species-specific traits, we specifically selected the mouse model for later in vivo studies. We first prepared the N-terminally Flag-tagged mouse (m) recombinant (r) soluble (s) fusion proteins mrsTLR4-IgGFc (T4Fc) and mrsMD-2 in Drosophila melanogaster Schneider 2 (S2) cells. The function of these molecules was tested by inhibition of synthesis of pro-inflammatory cytokines after stimulation of mouse macrophage RAW 264.7 cells with purified lipopolysaccharide (LPS). T4Fc alone had no inhibitory activity; however, a T4Fc/MD-2 complex blocked LPS activity. By analogy with 'cytokine traps', we then prepared a designer molecule (LPS-Trap) by fusing MD-2 to the C-terminus of soluble TLR4 via a flexible linker. LPS-Trap significantly inhibited TNF production by LPS-stimulated RAW 264.7 cells. Thus, the T4Fc/MD-2 complex as well as the LPS-Trap blocked LPS activity in vitro and might thus represent a new therapeutic option in sepsis by neutralization of TLR4-activating ligands.

  5. Physical Properties of Near-Earth Asteroid 2011 MD

    NARCIS (Netherlands)

    Mommert, M.; Farnocchia, D.; Hora, J. L.; Chesley, S. R.; Trilling, D. E.; Chodas, P. W.; Mueller, M.; Harris, A. W.; Smith, H. A.; Fazio, G. G.

    2014-01-01

    We report on observations of near-Earth asteroid 2011 MD with the Spitzer Space Telescope. We have spent 19.9 h of observing time with channel 2 (4.5 {\\mu}m) of the Infrared Array Camera and detected the target within the 2{\\sigma} positional uncertainty ellipse. Using an asteroid thermophysical mod

  6. MD SIMULATION OF SUBTILISIN BPN' IN A CRYSTAL ENVIRONMENT

    NARCIS (Netherlands)

    HEINER, AP; BERENDSEN, HJC; VANGUNSTEREN, WF

    1992-01-01

    In this paper we present a molecular dynamics (MD) simulation of subtilisin BPN' in a crystalline environment containing four protein molecules and solvent. Conformational and dynamic properties of the molecules are compared with each other and with respect to the X-ray structure to test the validit

  7. Physical Properties of Near-Earth Asteroid 2011 MD

    NARCIS (Netherlands)

    Mommert, M.; Farnocchia, D.; Hora, J. L.; Chesley, S. R.; Trilling, D. E.; Chodas, P. W.; Mueller, M.; Harris, A. W.; Smith, H. A.; Fazio, G. G.

    2014-01-01

    We report on observations of near-Earth asteroid 2011 MD with the Spitzer Space Telescope. We have spent 19.9 h of observing time with channel 2 (4.5 {\\mu}m) of the Infrared Array Camera and detected the target within the 2{\\sigma} positional uncertainty ellipse. Using an asteroid thermophysical

  8. Synonymy of Plotococcus Miller & Denno with Leptococcus Reyne, and description of a new species from Colombia (Hemiptera: Pseudococcidae).

    Science.gov (United States)

    Kondo, Takumasa; Gullan, Penny J

    2008-01-01

    Plotococcus Miller & Denno is synonymized with Leptococcus Reyne (Coccoidea: Pseudococcidae). The genus is redescribed and the adult female of the type species, L. metroxyli Reyne, is redescribed and illustrated. All species hitherto included in Plotococcus are transferred to Leptococcus as L. capixaba (Kondo) comb. nov., L. eugeniae (Miller & Denno) comb. nov., L. hambletoni (Kondo) comb. nov., L. minutus (Hempel) comb. nov., and L. neotropicus (Williams & Granara de Willink) comb. nov. A new species of Leptococcus, L. rodmani Kondo sp. n., from leaves of Guarea guidonia (Meliaceae) from Colombia, is described and illustrated based on the adult female. A revised key to adult females of all species in the genus is provided.

  9. ″Moving inward as well as north″: The Historical Imagination in Arthur Miller's The Crucible and Timebends

    Institute of Scientific and Technical Information of China (English)

    Douglas Tallack

    2005-01-01

    Arthur Miller, one of the most admirable of Americans to come out of the ″American century″, died in 2005, aged 89. In the UK, at least, his work has undergone a revival and the themes of his great plays remain resonant, even though, in many respects, they are historically specific. The relationship between literature and history - whether conceived as a symbolist or allegorical relationship - together with an instance of the past invading the present, are brought out in a compelling episode in Miller's autobiography, Timebends, and offer a way of talking about those inter-connections in The Crucible.

  10. The Innocent in the Strange World-The Application of Reader Theory in the Interpretation of Daisy Miller

    Institute of Scientific and Technical Information of China (English)

    LIU Li-hua

    2014-01-01

    Henry James’s first novella Daisy Miller brought him popularity and literary reputation after its publication. Through the application of reader theory and a close reading of the text, this article analyzes Daisy’s strong personality and her misfortunes during her trip to Europe, and reveals how the novella highlights the conflict between American frankness and innocence and Eu-ropean sophistication. Besides, this article also elaborates on James’unique artistic skills-central consciousness and psychological analysis through his choice of narrative point of view, which contribute to the theme and the artistic charm of Daisy Miller.

  11. Treatment of Multiple Adjacent Miller Class III Gingival Recessions with a Modified Tunnel Technique: A Case Series.

    Science.gov (United States)

    Yaman, Duygu; Demirel, Korkud; Aksu, Seden; Basegmez, Cansu

    2015-01-01

    Modified coronally advanced tunnel (MCAT) technique with connective tissue graft (CTG) was used in treating multiple adjacent Miller Class III gingival recessions in nine patients. Clinical evaluations were recorded at baseline and 12 months after surgery. The results showed that 50% of complete root coverage and 78% of mean root coverage were attained 1 year after surgery and interdental space fill was 73% at 12 months. The study demonstrated that CTG using the MCAT technique may be an efficient way to treat multiple adjacent Miller Class III gingival recessions, especially when aiming for interdental space fill. Success, however, seems to be related to the amount of tissue present initially.

  12. THE AMERICAN PROPHET: THE INFLUENCE OF THE PROPHETIC ON MARTIN LUTHER KING JR

    OpenAIRE

    Ritchie, David T.

    2010-01-01

    The foundations of U.S. civil rights pioneer Martin Luther King Jr.’s thought are as variedand diverse as his vision for a new American society. As a Baptist minister his ideas were of courseshaped by the Christian ideals of that faith. He was also influenced, however, by religious and secularideals from other traditions. In this article I discuss the effect of the work of the Jewish theologian andsocial philosopher Martin Buber on King’s philosophy. In particular, I examine how Buber’s notio...

  13. In Memoriam of John T. Yates Jr. (August 3, 1935 - September 26, 2015)

    Science.gov (United States)

    Russell, John N.; Beebe, Thomas P.

    2016-10-01

    John T. Yates, Jr., Professor of Chemistry at the University of Virginia, member of the US National Academy of Sciences, and a pioneer of modern surface science, passed away at his home on Saturday morning September 26, 2015, from a recurring glioblastoma. John was both courageous, pragmatic and forthright about his diagnosis right to the end. His wife, Kerin, related that John, upon learning of his diagnosis, said that he had had a great life and was not going to 'let the last 1.25%' define him. It did not. He had a wonderful family and a stellar career.

  14. Suzaku observations of the hard X-ray spectrum of Vela Jr

    CERN Document Server

    Takeda, Sawako; Terada, Yukikatsu; Tashiro, Makoto S; Katsuda, Satoru; Yamazaki, Ryo; Ohira, Yutaka; Iwakiri, Wataru

    2016-01-01

    We report the results of Suzaku observations of the young supernova remnant, Vela Jr.\\ (RX J0852.0$-$4622), which is known to emit synchrotron X-rays, as well as TeV gamma-rays. Utilizing 39 Suzaku mapping observation data from Vela Jr., a significant hard X-ray emission is detected with the hard X-ray detector (HXD) from the north-west TeV-emitting region. The X-ray spectrum is well reproduced by a single power-law model with the photon index of 3.15$^{+1.18}_{-1.14}$ in the 12--22 keV band. Compiling this with the soft X-ray spectrum simultaneously observed with the X-ray imaging spectrometer (XIS) onboard Suzaku, we find that the wide-band X-ray spectrum in the 2--22 keV band is reproduced with a single power-law or concave broken power-law model, which are statistically consistent with each other. Whichever the model of a single or broken power-law is appropriate, clearly the spectrum has no rolloff structure. Applying this result to the method introduced in \\citet{yama2014}, we find that one-zone synchro...

  15. The leadership principles of Dr. Martin Luther King, Jr. and their relevance to surgery.

    Science.gov (United States)

    Brunicardi, F Charles; Cotton, Ronald T; Cole, George W; Martinez, George

    2007-01-01

    In order to face the challenges in healthcare this century, it is essential that surgeons understand modern leadership principles. One of the greatest leaders in history was Dr. Martin Luther King, Jr., who provides a shining example of level-5 leadership for us to study. The study of leadership principles of great leaders can provide us with practical methods of conflict resolution as well as inspiration to keep us engaged and focused. As leaders of the medical community, we face numerous challenges, including discovering and implementing new treatments for disease, providing care for the indigent, overcoming educational challenges such as incorporating the ACGME Core Competencies into our surgical training and promoting diversity in education. Achieving these goals is often hindered by the environment in which we labor-nearly 50 million are uninsured, the rising cost of medical care is currently at 16% of the GNP, and reimbursement rates are falling-which makes the practice of surgery a significant challenge. Effective leadership will be paramount in achieving these goals. In this editorial, which summarizes a presentation given to the Surgical Section of the annual National Medical Association meeting, five important leadership principles that are important for surgeons have been selected and related to the outstanding leadership of Dr. Martin Luther King, Jr.

  16. Miller-Fisher Syndrome: Are Anti-GAD Antibodies Implicated in Its Pathophysiology?

    Directory of Open Access Journals (Sweden)

    Ioannis E. Dagklis

    2016-01-01

    Full Text Available Miller-Fisher syndrome (MFS is considered as a variant of the Guillain-Barre syndrome (GBS and its characteristic clinical features are ophthalmoplegia, ataxia, and areflexia. Typically, it is associated with anti-GQ1b antibodies; however, a significant percentage (>10% of these patients are seronegative. Here, we report a 67-year-old female patient who presented with the typical clinical features of MFS. Workup revealed antibodies against glutamic acid decarboxylase (GAD in relatively high titers while GQ1b antibodies were negative. Neurological improvement was observed after intravenous gamma globulin and follow-up examinations showed a continuous clinical amelioration with simultaneous decline of anti-GAD levels which finally returned to normal values. This case indicates that anti-GAD antibodies may be associated with a broader clinical spectrum and future studies in GQ1b-seronegative patients could determine ultimately their clinical and pathogenetic significance in this syndrome.

  17. Dameshek W, Miller EB. The megakaryocytes in idiopathic thrombocytopenic purpura, a form of hypersplenism. 1946.

    Science.gov (United States)

    2016-01-01

    This paper, by one of the legends of hematology, William Dameshek, and his colleague Edward Miller, is from the inaugural issue of Blood. By studying bone marrow specimens from controls, patients with acute or chronic immune thrombocytopenia, or patients with other thrombocytopenic disorders, the authors concluded that, in idiopathic thrombocytopenic purpura (ITP), production of platelets from megakaryocytes is defective, even while marrow megakaryocytes are greatly increased in number. This defect resolved after splenectomy. The authors appropriately credit E. Frank with having proposed defective platelet production from megakaryocytes in ITP in 1915. The idea that platelet production was defective in ITP was superseded or ignored for decades, but it has now been validated by the therapeutic effectiveness of the thrombopoietin mimetics in ITP.

  18. Flagg Miller, The Moral Resonance of Arab Media: Audiocassette Poetry and Culture in Yemen

    Directory of Open Access Journals (Sweden)

    Jean Lambert

    2008-04-01

    Full Text Available Le livre de Flagg Miller est la publication de sa thèse de doctorat, rédigée à la suite d’enquêtes de terrain conduites au milieu des années quatre-vingt dix, dans la région de Yâfi‘. L’ouvrage traite principalement de la poésie bid‘ wa jiwâb (que l’on peut traduire sommairement par « initiative et réponse », une sorte de joute poétique à distance : un poème est composé sur la forme de poème monorime, qasîda, en général de critique sociale ou politique, souvent chanté par un musicien spécial...

  19. Predictive accuracy of the Miller assessment for preschoolers in children with prenatal drug exposure.

    Science.gov (United States)

    Fulks, Mary-Ann L; Harris, Susan R

    2005-01-01

    The Miller Assessment for Preschoolers (MAP) is a standardized test purported to identify preschool-aged children at risk for later learning difficulties. We evaluated the predictive validity of the MAP Total Score, relative to later cognitive performance and across a range of possible cut-points, in 37 preschool-aged children with prenatal drug exposure. Criterion measures were the Wechsler Preschool & Primary Scale of Intelligence-Revised (WPPSI-R), Test of Early Reading Ability-2, Peabody Picture Vocabulary Test-Revised, and Developmental Test of Visual Motor Integration. The highest predictive accuracy was demonstrated when the WPPSI-R was the criterion measure. The 14th percentile cutoff point demonstrated the highest predictive accuracy across all measures.

  20. Aleksei Miller ja "uus impeeriumi ajalugu" / Toomas Karjahärm

    Index Scriptorium Estoniae

    Karjahärm, Toomas, 1944-

    2011-01-01

    Arvustus: Миллер, Алексей. Империя Романовых и национализм : эссе по методологии исторического исследования. Москва : Новое Литературное Обозрение, 2008. (Historica Rossica). Polüetnilisi impeeriume eelistab Miller käsitleda mitte regionaalsete, vaid situatiivsete kategooriatega

  1. Miller Fisher syndrome: a rare variant of Guillain-Barré syndrome

    Directory of Open Access Journals (Sweden)

    Luciana Pinto Bandeira

    2012-12-01

    Full Text Available This report describes the case of a 39-year-old male patient who presented to the emergency room with complaints of impaired balance, diplopia, and nasal voice. The patient had a history of upper respiratory tract infection. The initial physical examination revealed ataxia, ophthalmoplegia, and areflexia, which are consistent with the classic triad of Miller Fisher syndrome, considered a benign variant of Guillain-Barré syndrome. The patient developed peripheral facial paralysis during hospitalization. He underwent a treatment with immunoglobulin for five days, resulting in near complete resolution of the ataxia. However, the ophthalmoplegia and areflexia persisted. He was discharged to outpatient follow-up.

  2. Acetylcholine causes rooting in leaf explants of in vitro raised tomato (Lycopersicon esculentum Miller) seedlings.

    Science.gov (United States)

    Bamel, Kiran; Gupta, Shrish Chandra; Gupta, Rajendra

    2007-05-30

    The animal neurotransmitter acetylcholine (ACh) induces rooting and promotes secondary root formation in leaf explants of tomato (Lycopersicon esculentum Miller var. Pusa Ruby), cultured in vitro on Murashige and Skoog's medium. The roots originate from the midrib of leaf explants and resemble taproot. ACh at 10(-5) M was found to be the optimum over a wide range of effective concentrations between 10(-7) and 10(-3) M. The breakdown products, choline and acetate were ineffective even at 10(-3) M concentration. ACh appears to have a natural role in tomato rhizogenesis because exogenous application of neostigmine, an inhibitor of ACh hydrolysis, could mimic the effect of ACh. Neostigmine, if applied in combination with ACh, potentiated the ACh effect.

  3. Performance of Hispanic inmates on the Spanish Miller Forensic Assessment of Symptoms Test (M-FAST).

    Science.gov (United States)

    Montes, Orbelin; Guyton, Michelle R

    2014-10-01

    The few psychological assessment measures commercially available for the assessment of Spanish-speaking populations lack strong empirical foundation. This is concerning given the rising numbers of Spanish speakers entering the forensic and correctional systems for whom valid assessment is difficult without linguistically and culturally appropriate measures. In this study, we translated and adapted the Miller Forensic Assessment of Symptoms Test (M-FAST) into Spanish. The general purpose of this study was to investigate the psychometric, linguistic, and conceptual equivalence of the English- and Spanish-language versions of the M-FAST in a sample of 102 bilingual Hispanic incarcerated males. Participants were randomly assigned to one of three feigning conditions (honest, uncoached, or coached) and completed the M-FAST in both English and Spanish on two separate occasions. Both language versions were psychometrically, linguistically, and conceptually equivalent.

  4. Aleksei Miller ja "uus impeeriumi ajalugu" / Toomas Karjahärm

    Index Scriptorium Estoniae

    Karjahärm, Toomas, 1944-

    2011-01-01

    Arvustus: Миллер, Алексей. Империя Романовых и национализм : эссе по методологии исторического исследования. Москва : Новое Литературное Обозрение, 2008. (Historica Rossica). Polüetnilisi impeeriume eelistab Miller käsitleda mitte regionaalsete, vaid situatiivsete kategooriatega

  5. Mycocoenology in Abies alba Miller woods of central-southern Tuscany (Italy

    Directory of Open Access Journals (Sweden)

    Angela Laganà

    2014-01-01

    Full Text Available Numerous reports indicate that fir woods in central and northern Europe have recently been damaged by increasing pollution. It has been demonstrated that fungi can be good bioindicators of forest health status. In polluted areas the production of fruit bodies generally declines and the fungal biodiversity, especially of symbiotic species, is reduced. Here we report the results of a survey of the fungal and plant communities in woods of Abies alba Miller in central-southern Tuscany, already studied in the past. Certain changes were observed in the study areas, but they seem more likely to be due to other factors than pollution, such as the weather conditions, the age and natural evolution of the forests towards their climax.

  6. I teoremi di Modigliani-Miller: una pietra miliare della finanza

    Directory of Open Access Journals (Sweden)

    Marco Pagano

    2005-06-01

    Full Text Available I teoremi di Modigliani e Miller (MM sono una pietra miliare della finanza per due ragioni.La prima è sostanziale e deriva dalla loro natura di “proposizioni di irrilevanza”: essi individuano un caso in cui la struttura finanziaria e la politica dei dividendi non influiscono sul valore delle imprese, e così facendo ci danno un chiaro punto di riferimento per capire in quali circostanze invece queste decisioni influiscono sul valore delle imprese, e perché. In effetti, l’intera evoluzione successiva della finanza aziendale ha esplorato le conseguenze della rimozione delle ipotesi di MM. La seconda ragione dell’importanza fondamentale deiteoremi di MM è di tipo metodologico: essi sono stati dimostrati con un ragionamento basato sull’arbitraggio, il che ha stabilito un precedente non solo nel campo della finanza aziendale ma anche e soprattutto in quello della determinazione dei prezzi dei titoli finanziari.

  7. OPTIMIZATION OF MICROWAVE AND AIR DRYING CONDITIONS OF QUINCE (CYDONIA OBLONGA, MILLER USING RESPONSE SURFACE METHODOLOGY

    Directory of Open Access Journals (Sweden)

    Cem Baltacioglu

    2015-03-01

    Full Text Available Effects of slice thickness of quince (Cydonia oblonga Miller , microwave incident power and air drying temperature on antioxidant activity and total phenolic content of quince were investigated during drying in microwave and air drying. Optimum conditions were found to be: i for microwave drying, 285 W and 4.14 mm thick (maximum antioxidant activity and 285 W and 6.85 mm thick (maximum total phenolic content, and ii for air drying, 75 ºC and 1.2 mm thick (both maximum antioxidant activity and total phenolic content. Drying conditions were optimized by using the response surface methodology. 13 experiments were carried out considering incident microwave powers from 285 to 795 W, air temperature from 46 to 74 ºC and slice thickness from 1.2 to 6.8 mm.

  8. Teorema Modigliani-Miller, imperfetta informazione e meccanismo di trasmissione della politica monetaria

    Directory of Open Access Journals (Sweden)

    G. BERTOCCO

    1995-09-01

    Full Text Available The work first aims to show that the Modigliani-Miller theorem can not constitute the theoretical foundation of traditional analysis. It then analyses the consequences of the presence of imperfect information on the characteristics of the transmission mechanism of monetary policy. It is observed that the dependence on commercial bank credit is not a sufficient condition for operating a transmission mechanism based on the control of the amount of credit that is different from the traditional mechanism. If the banking system could isolate the supply of credit through central bank decisions, the effects of monetary policy would be transmitted through interest rates, as established traditional analysis. The author shows that the characteristics of the transmission mechanism of monetary policy do not depend only on the presence of imperfect information, but also on the assumptions regarding the determination of the supply of credit.

  9. Current Perioperative Management of Anticoagulant and Antiplatelet Use in Neuroendovascular Therapy: Analysis of JR-NET1 and 2

    Science.gov (United States)

    ENOMOTO, Yukiko; YOSHIMURA, Shinichi; SAKAI, Nobuyuki; EGASHIRA, Yusuke

    2014-01-01

    To evaluate current perioperative antithrombotic management in neuroendovascular therapy in Japan, we analyzed perioperative anticoagulant and antiplatelet use in various procedures and examined their relationships with periprocedural adverse events. Patient's data from nationwide surveys administered by the Japanese Registry of Neuroendovascular Therapy (JR-NET) between January 2005 and December 2007 (JR-NET1) and January 2008 and December 2009 (JR-NET2) were retrospectively analyzed. Compared to JR-NET1, the frequency of perioperative antiplatelet therapy and dual or triple therapy were increased for either aneurysm coiling and percutaneous transluminal angioplasty or stenting in JR-NET2. Although ischemic complications were significantly decreased (4.2% vs. 2.1%, p antiplatelet therapy (preoperative: 5.3% vs. 9.2%, p therapy was performed more frequently and intensively in neuroendovascular therapy in Japan. While ischemic complications were decreased, hemorrhagic complications and severe adverse events were increased. These results suggest that intensive antithrombotic therapy has a potential risk of hemorrhagic complications for Japanese patients. PMID:24305029

  10. 5 YEAR PHYSIOTHERAPY AND REHABILITATION RESULTS OF THE PATIENT WITH MILLER FISHER SYNDROME

    Directory of Open Access Journals (Sweden)

    Bihter AKINOĞLU

    2016-08-01

    Full Text Available Background: Miller-Fisher syndrome (MFS is characterized by gait ataxia, external ophtalmoplegia and areflexia and thought as an uncommon variant of Guillain Barre syndrome. Miller-Fisher syndrome is observed in about 5-8% of all Guillain Barre syndrome (GBS cases. In MFS patients, spontaneous improvement was observed in the first 3 months and these improvements were started by the 2nd week. Methods: This case was referred to physiotherapy and rehabilitation program at the 4th week since the appropriate medical treatments were unsuccessful after the attack. The patient was evaluated generally before physiotherapy program, and muscle length, strength loss, deep tendon reflexes, postural impairments and daily difficult activities and positions were assessed. Besides, the desired daily activities were identified by The Canadian Occupational Performance Measure (COPM. Treatment program was adjusted according to the patient and changes during treatment period were observed. Physiotherapy program included classical physiotherapy methods: posture correction, correction of short muscles, muscle strengthening, flexibility increase, balance/coordination, sitting and standing functions and walking improvement and climbing up stairs. Results: After the treatment, lower extremity muscle shortness decreased and muscle strength, standing on one foot duration, independent walk speed increased in time. Before treatment, he could not climbing upstairs, but it was achieved 1 year after the treatment. Berg balance score increased in time and his most desired activities by COPM (10/10 were could be performed after the treatment. Conclusion: The case improved with physiotherapy and rehabilitation program gradually with years.In the treatment of MFS patients, physiotherapy and rehabilitation being part of the treatment will be useful.

  11. A Short Study on the Validity of Miller's Theorem Applied to Transistor Amplifier High-Frequency Performance

    Science.gov (United States)

    Schubert, T. F., Jr.; Kim, E. M.

    2009-01-01

    The use of Miller's Theorem in the determination of the high-frequency cutoff frequency of transistor amplifiers was recently challenged by a paper published in this TRANSACTIONS. Unfortunately, that paper provided no simulation or experimental results to bring credence to the challenge or to validate the alternate method of determination…

  12. A Short Study on the Validity of Miller's Theorem Applied to Transistor Amplifier High-Frequency Performance

    Science.gov (United States)

    Schubert, T. F., Jr.; Kim, E. M.

    2009-01-01

    The use of Miller's Theorem in the determination of the high-frequency cutoff frequency of transistor amplifiers was recently challenged by a paper published in this TRANSACTIONS. Unfortunately, that paper provided no simulation or experimental results to bring credence to the challenge or to validate the alternate method of determination…

  13. Comment on ``Subtleties of Lorentz invariance and Shapes of the Nucleon'' by Alexander Kvinikhidze and Gerald A. Miller

    CERN Document Server

    Gross, Franz; Peña, M T

    2007-01-01

    Addressing the recent criticisms of Kvinikhidze and Miller, we prove that the spectator wave functions and currents based on ``fixed-axis'' polarization states (previously introduced by us) are Lorentz covariant, and find an explicit connection between them and conventional direction-dependent polarization states. The discussion shows explicitly how it is possible to construct pure $S$-wave models of the nucleon.

  14. Comparative evaluation of the effect of chlorhexidine and Aloe barbadensis Miller (Aloe vera) on dentin stabilization using shear bond testing

    Science.gov (United States)

    Sinha, Dakshita Joy; Jaiswal, Natasha; Vasudeva, Agrima; Garg, Paridhi; Tyagi, Shashi Prabha; Chandra, Priyanka

    2016-01-01

    Introduction: The main objective of adhesive dentistry is to create an effective, durable union between the tooth structure and restorative material. However, degradation of adhesive dentine interface remains largely responsible for the relatively short lifetime of tooth colored resin restoration. Aim: The aim of the study is to compare the dentin collagen stabilization property of Chlorhexidine (CHX) and Aloe barbadensis Miller using shear bond strength testing. Materials and Methods: Occlusal reduction was done in sixty extracted human mandibular molars to expose the mid coronal dentin and divided into three groups n = 20. Following the surface pretreatment (Group 1 = control, Group 2 = CHX, Group 3 = Aloevera), dentine bonding agent and composite resin were applied and cured. The specimens were then subjected to shear bond strength testing. Results: From the results analyzed, it was noted that there was statistically significant difference between the groups Control and CHX and Control and A. barbadensis Miller (P 0.05). Hence, the following result for the shear bond strengths to dentin was obtained: Control < CHX ≈ A. barbadensis Miller. Conclusion: CHX and A. barbadensis Miller, as pretreatment agents of acid demineralized dentin collagen, has no adverse effect on the immediate shear bond strength of a two-step etch and rinse adhesive to dentin. PMID:27656056

  15. MONITORING AND BLUNTING COPING STYLES - THE MILLER BEHAVIORAL STYLE SCALE AND ITS CORRELATES, AND THE DEVELOPMENT OF AN ALTERNATIVE QUESTIONNAIRE

    NARCIS (Netherlands)

    MURIS, P; VANZUUREN, FJ; de Jong, Peter; DEBEURS, E; HANEWALD, G

    1994-01-01

    The present article presents two studies concerning the measurement of monitoring (information seeking under threat) and blunting (information avoidance) coping styles. Study 1 (n = 69) showed that the widely used Miller Behavioural Style Scale suffers from a number of weaknesses such as insufficien

  16. A CLINICAL ASSESSMENT OF MACINTOSH BLADE, MILLER BLADE AND KING VISIONTM VIDEOLARYNGOSCOPE FOR LARYNGEAL EXPOSURE AND DIFFICULTY IN ENDOTRACHEAL INTUBATION

    Directory of Open Access Journals (Sweden)

    Apoorva Mahendera

    2016-03-01

    Full Text Available CONTEXT Previous studies suggest glottic view is better achieved with straight blades while tracheal intubation is easier with curved blades and videolaryngoscope is better than conventional laryngoscope. AIMS Comparison of conventional laryngoscope (Macintosh blade and Miller blade with channelled videolaryngoscope (King Vision TM with respect to laryngeal visualisation and difficulty in endotracheal intubation. SETTINGS AND DESIGN This prospective randomised comparative study was conducted at a tertiary care hospital (in ASA I and ASA II patients after approval from the Institutional Ethics Committee. METHODS We compared Macintosh, Miller, and the King VisionTM videolaryngoscope for glottic visualisation and ease of tracheal intubation. Patients undergoing elective surgeries under general anaesthesia requiring endotracheal intubation were randomly divided into three groups (N=180. After induction of anaesthesia, laryngoscopy was performed and trachea intubated. We recorded visualisation of glottis (Cormack-Lehane grade-CL, ease of intubation, number of attempts, need to change blade, and need for external laryngeal manipulation. STATISTICAL ANALYSIS Demographic data, Mandibular length, Mallampati classification were compared using ANOVA, Chi-square test, Kruskal-Wallis Test, where P value <0.005 is statically significant. RESULTS CL grade 1 was most often observed in King Vision -TM VL group (90% which is followed by Miller (28.33%, and Macintosh group (15%. We found intubation was to be easier (grade 1 with King Vision -TM VL group (73.33%, followed by Macintosh (38.33%, and Miller group (1.67%. External manipulation (BURP was needed more frequently in patients in Miller group (71.67%, followed by Macintosh (28.33% and in King Vision -TM VL group (6.67%. All (100% patients were intubated in the 1 st attempt with King Vision -TM VL group, followed by Macintosh group (90% and Miller group (58.33%. CONCLUSIONS In patients with normal airway

  17. MD 382: Beam Transfer Function and diffusion mechanisms

    CERN Document Server

    Tambasco, Claudia; Buffat, Xavier; Crouch, Matthew; Pieloni, Tatiana; Boccardi, Andrea; Fuchsberger, Kajetan; Gasior, Marek; Kotzian, Gerd; Lefevre, Thibaut; Pojer, Mirko; Salvachua Ferrando, Belen Maria; Solfaroli Camillocci, Matteo; Giachino, Rossano; CERN. Geneva. ATS Department

    2016-01-01

    The Beam Transfer Function (BTF) measurements have been previously tested in the LHC during MD block 1 and 2. Different machine configurations (i.e. energy, beam intensity, emittance etc...) have been tested to determine a safe set-up (excitation amplitude) of the system to be completely transparent to the beam (no emittance blow-up neither losses). The aim of this experiment in MD block 3 was to characterize the Stability Diagram (SD) in the presence of diffusion mechanisms induced by excited resonances due to beam-beam long range and Landau octupole interplay. During the experiment, BTF measurements have been acquired at flat top for different settings of Landau octupole current, different chromaticity values and transverse feedback gains. In this note the description of the experiment is presented together with some preliminary results.

  18. A Fast Attack Algorithm on the MD5 Hash Function

    Institute of Scientific and Technical Information of China (English)

    WANG Zhang-yi; ZHANG Huan-guo; QIN Zhong-ping; MENG Qing-shu

    2006-01-01

    The sufficient conditions for keeping desired differential path of MD5 was discussed. By analyzing the expanding of subtraction difference, differential characters of Boolean functions, and the differential characters of shift rotation, the sufficient conditions for keeping desired differential path could be obtained. From the differential characters of shift rotation, the lacked sufficient conditions were found. Then an algorithm that reduces the number of trials for finding collisions were presented. By restricting search space, search operation can be reduced tc 234 for the first block and 230 for the second block. The whole attack on the MD5 can be accomplished within 2C hours using a PC with 1.6 G CPU.

  19. MD210 Note: Creation of Hollow Bunches in the PSB

    CERN Document Server

    Oeftiger, Adrian; Findlay, Alan James; Hancock, Steven; Rumolo, Giovanni; CERN. Geneva. ATS Department

    2016-01-01

    MD210 aims for the creation of longitudinally hollow bunches in the CERN PS Booster. The first three sessions have been carried out using the radial loop feedback system in order to drive the beam on a dipolar parametric resonance (instead of the phase loop). It has been found that the damping by the phase loop inhibits the excitation of the resonance to a major extent. The hollow distributions generated under these circumstances fail to reach a satisfying bunching factor. Nonetheless, proving the principally successful application of this technique to the PS Booster promises good results once the phase loop system supports trim functions. The approach, actions and detailed results of the first three MD sessions are presented in this paper.

  20. MD 1856 - Landau Damping: Beam Transfer Functions and diffusion mechanisms

    CERN Document Server

    Tambasco, Claudia; Boccardi, Andrea; Buffat, Xavier; Gasior, Marek; Lefevre, Thibaut; Levens, Tom; Pojer, Mirko; Salvachua Ferrando, Belen Maria; Solfaroli Camillocci, Matteo; Pieloni, Tatiana; Crouch, Matthew Paul; CERN. Geneva. ATS Department

    2017-01-01

    In the 2012, 2015 and 2016 several instabilities were developing during the betatron squeeze where beam-beam interactions become stronger modifying the tune spread provided by the octupoles magnets. Studies of the stability area computed by evaluating the dispersion integral for different tune spread couldn’t explain the 2012 observed instabilities during the squeeze. The size of the stability area given by the computed dispersion integral depends on the transverse tune spread but its shape is defined by the particle distribution in the beams. Therefore any change of the particle distribution due to for instance a diffusion from excited resonances can lead to a deterioration of the Landau stability area. The Beam Transfer Functions (BTF) measurements are direct measurement of the Stability Diagrams (SD). They are sensitive to the particle distribution and contain information about the transverse tune spread in the beams. In this MD we wanted to verify the findings of MD 1407 and try to explain observed inst...

  1. MD 349: Impedance Localization with AC-dipole

    CERN Document Server

    Biancacci, Nicolo; Metral, Elias; Salvant, Benoit; Papotti, Giulia; Persson, Tobias Hakan Bjorn; Tomas Garcia, Rogelio; CERN. Geneva. ATS Department

    2016-01-01

    The purpose of this MD is to measure the distribution of the transverse impedance of the LHC by observing the phase advance variation with intensity between the machine BPMs. Four injected bunches with different intensities are excited with an AC dipole and the turn by turn data is acquired from the BPM system. Through post-processing analysis the phase variation along the machine is depicted and, from this information, first conclusions of the impedance distribution can be drawn.

  2. MD 1691: Active halo control using tune ripple at injection

    CERN Document Server

    Garcia Morales, Hector; Bruce, Roderik; Redaelli, Stefano; Fitterer, Miriam; Fiascaris, Maria; Nisbet, David; Thiesen, Hugues; Valentino, Gianluca; Xu, Chen; CERN. Geneva. ATS Department

    2017-01-01

    In this MD we performed halo excitation through tune ripple. This consists in an excitation that introduces new resonance sidebands around the existing resonance lines. In presence of sufficient detuning with amplitude, these sidebands can in principle affect only the dynamics of the halo particles at large amplitudes. Tune ripple was induced through a current modulation of the warm trim quadrupoles in IR7. This is the first time this method is experimentally tested at the LHC.

  3. Application of MD simulations to predict membrane properties of MOFs

    OpenAIRE

    Elda Adatoz; Seda Keskin

    2015-01-01

    Research Article Application of MD Simulations to Predict Membrane Properties of MOFs Elda Adatoz and Seda Keskin Chemical and Biological Engineering, Koc University, Rumelifeneri Yolu, Sariyer, 34450 Istanbul, Turkey Correspondence should be addressed to Seda Keskin; Received 22 May 2015; Accepted 13 July 2015 Academic Editor: Yanlin Song Copyright © 2015 E. Adatoz and S. Keskin. This is an open access article distributed under the Creative Commons A...

  4. Analytical applications of MD-FIA-optical detection systems

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    A brief introduction of recent research works in our laboratory concerning microdialysis(MD) based on optical detection combined with FIA is made in this mini-review. A biosensor system has been designed and realized the real time in vivo monitoring of some important clinic substances such as calcium, uric acid. The system has also been used to study the in vitro binding of drug-protein.

  5. Summary of LHC MD:377: Schottky pick-up

    CERN Document Server

    Betz, Michael; Lefevre, Thibaut; CERN. Geneva. ATS Department

    2015-01-01

    The main objective of this MD was to record Schottky spectra under well known machine conditions. In summary, 7 set-points for the chromaticity and 8 for the emittance have been established and Schottky spectra have been recorded for each setting. The data will be used to benchmark and develop different fitting algorithms. This note presents the initial attempt of curve-fitting and discusses its shortcomings.

  6. Towards automatic coupling corrections with DOROS BPMs (MD750)

    CERN Document Server

    Persson, Tobias Hakan Bjorn; Langner, Andy Sven; Lefevre, Thibaut; Maclean, Ewen Hamish; Malina, Lukas; Olexa, Jakub; Skowronski, Piotr Krzysztof; Garcia-Tabares Valdivieso, Ana; Coello De Portugal - Martinez Vazquez, Jaime Maria; Tomas Garcia, Rogelio; CERN. Geneva. ATS Department

    2015-01-01

    BPMs close to IP1 and IP5 have been equipped with the new DOROS (Diode ORbit OScillation) system which provides precise orbit and turn-by-turn data [1]. In this MD-note we report on the rst measurements with the DOROS system to measure the transverse coupling. Furthermore, we compare the results and the performance of the system to the normal BPMs.

  7. Apple fruit copper amine oxidase isoforms: peroxisomal MdAO1 prefers diamines as substrates, whereas extracellular MdAO2 exclusively utilizes monoamines.

    Science.gov (United States)

    Zarei, Adel; Trobacher, Christopher P; Cooke, Alison R; Meyers, Ashley J; Hall, J Christopher; Shelp, Barry J

    2015-01-01

    4-Aminobutyrate (GABA) accumulates in apple fruit during controlled atmosphere storage. A potential source of GABA is the polyamine putrescine, which can be oxidized via copper-containing amine oxidase (CuAO), resulting in the production 4-aminobutanal/Δ(1)-pyrroline, with the consumption of O2 and release of H2O2 and ammonia. Five putative CuAO genes (MdAO genes) were cloned from apple (Malus domestica Borkh. cv. Empire) fruit, and the deduced amino acid sequences found to contain the active sites typically conserved in CuAOs. Genes encoding two of these enzymes, MdAO1 and MdAO2, were highly expressed in apple fruit and selected for further analysis. Amino acid sequence analysis predicted the presence of a C-terminal peroxisomal targeting signal 1 tripeptide in MdAO1 and an N-terminal signal peptide and N-glycosylation site in MdAO2. Transient expression of green fluorescent fusion proteins in Arabidopsis protoplasts or onion epidermal cells revealed a peroxisomal localization for MdAO1 and an extracellular localization for MdAO2. The enzymatic activities of purified recombinant MdAO1 and MdAO2 were measured continuously as H2O2 production using a coupled reaction. MdAO1 did not use monoamines or polyamines and displayed high catalytic efficiency for 1,3-diaminopropane, putrescine and cadaverine, whereas MdAO2 exclusively utilized aliphatic and aromatic monoamines, including 2-phenylethylamine and tyramine. Together, these results indicate that MdAO1 may contribute to GABA production via putrescine oxidation in the peroxisome of apple fruit under controlled atmosphere conditions. MdAO2 seems to be involved in deamination of 2-phenylethylamine, which is a step in the biosynthesis of 2-phenylethanol, a contributor to fruit flavor and flower fragrance.

  8. Implementation of MD5 Fast Decryption Algorithm Based on Graphic Processing Unit%基于GPU的MD5高速解密算法的实现

    Institute of Scientific and Technical Information of China (English)

    乐德广; 常晋义; 刘祥南; 郭东辉

    2010-01-01

    MD5快速碰撞算法由于不支持逆向过程而无法在MD5密码攻击中得到实际应用.针对上述问题,通过分析基于图形处理单元(GPU)的MD5密码并行攻击算法原理,设计基于GPU的MD5高速解密算法,在此基础上实现一个MD5高速密码攻击系统.测试结果证明,该算法能有效加快MD5密码破解速度.

  9. Book review: Martin’s dream: my journey and the legacy of Martin Luther King Jr.\\ud

    OpenAIRE

    McCormick, Roger

    2013-01-01

    "Martin’s Dream: My Journey and the Legacy of Martin Luther King Jr." Clayborne Carson. Palgrave Macmillan. January 2013. --- \\ud Written with the unique perspective of someone who has, for three decades, been involved with Martin Luther King Jr.’s legacy, Clayborne Carson gives readers an insider’s account of what transpired after the Dream speech, and beyond. A rich and engrossing memoir of black empowerment at a unique moment in time, this is an undoubtedly special contribution to King’s m...

  10. An initial survey of the cattle grub Dermatobia hominis (L. Jr.) in Nicaragua.

    Science.gov (United States)

    Villarino, Mario A; Garcia, Omar; Fussell, Weyman; Preston, Kelly; Wagner, Gale G

    2003-12-12

    After the civil war and the Hurricane-Mitch disaster, cattlemen in Nicaragua were forced to transport their cattle from lowland areas to higher, dryer areas of the country. These areas are natural ecological niches for the cattle grub Dermatobia hominis (L. Jr.) (Diptera: Cuterebridae). To determine the importance of this infestation, the Agricultural and Livestock-Forestry Ministry selected a central area of Nicaragua to run a pioneer survey program to acquire information about hosts involved, number of cases, treatments applied and general knowledge of 42 farmers about the life cycle of the parasite. The subjects were either farm owners or farm managers. Ninety-five percentage of the farms indicated cases of D. hominis infestation in their animals, with cattle being the most affected host (100% of the affected farms). There was poor understanding of the D. hominis life cycle, vectors and control methods. A misuse of insecticides for the treatment of larval infestation by D. hominis was indicated.

  11. Possessing History and American Innocence: James Baldwin, William F. Buckley, Jr., and the 1965 Cambridge Debate

    Directory of Open Access Journals (Sweden)

    Daniel Robert McClure

    2016-12-01

    Full Text Available The 1965 debate at Cambridge University between James Baldwin and William F. Buckley, Jr., posed the question: “Has the American Dream been achieved at the Expense of the American Negro?” Within the contours of the debate, Baldwin and Buckley wrestled with the ghosts of settler colonialism and slavery in a nation founded on freedom and equality. Framing the debate within the longue durée, this essay examines the deep cultural currents related to the American racial paradox at the height of the Civil Rights movement. Underscoring the changing language of white resistance against black civil rights, the essay argues that the Baldwin and Buckley debate anticipated the ways the U.S. would address racial inequality in the aftermath of the civil rights era and the dawn of neoliberalism in the 1970s.

  12. Collected Papers in Structural Mechanics Honoring Dr. James H. Starnes, Jr.

    Science.gov (United States)

    Knight, Norman F., Jr. (Compiler); Nemeth, Michael P. (Compiler); Malone, John B. (Compiler)

    2006-01-01

    This special publication contains a collection of structural mechanics papers honoring Dr. James H. Starnes, Jr. presented at the 46th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference held in Austin, Texas, April 18-21, 2005. Contributors to this publication represent a small number of those influenced by Dr. Starnes' technical leadership, his technical prowess and diversity, and his technical breath and depth in engineering mechanics. These papers cover some of the research areas Dr. Starnes investigated, which included buckling, postbuckling, and collapse of structures; composite structural mechanics, residual strength and damage tolerance of metallic and composite structures; and aircraft structural design, certification and verification. He actively pursued technical understanding and clarity, championed technical excellence, and modeled humility and perseverance.

  13. Julius H. Comroe, Jr., distinguished lecture: central chemoreception: then ... and now.

    Science.gov (United States)

    Nattie, Eugene

    2011-01-01

    The 2010 Julius H. Comroe, Jr., Lecture of the American Physiological Society focuses on evolving ideas in chemoreception for CO₂/pH in terms of what is "sensed," where it is sensed, and how the sensed information is used physiologically. Chemoreception is viewed as involving neurons (and glia) at many sites within the hindbrain, including, but not limited to, the retrotrapezoid nucleus, the medullary raphe, the locus ceruleus, the nucleus tractus solitarius, the lateral hypothalamus (orexin neurons), and the caudal ventrolateral medulla. Central chemoreception also has an important nonadditive interaction with afferent information arising at the carotid body. While ventilation has been viewed as the primary output variable, it appears that airway resistance, arousal, and blood pressure can also be significantly affected. Emphasis is placed on the importance of data derived from studies performed in the absence of anesthesia.

  14. Gunshot wounds to the hand. The Martin Luther King, Jr, General Hospital experience.

    Science.gov (United States)

    Phillips, P; Hansraj, K K; Cox, E E; Ashley, E M

    1995-01-01

    This article is a retrospective review of patients who presented to Martin Luther King, Jr./Drew Medical Center with gunshot wounds and had either isolated or associated injuries to the hand. The following is an account of those injuries noting the location, soft-tissue or bony involvement, and interventional methods that were implemented in the treatment of these patients who resided primarily in South Central Los Angeles. Prompt evaluation and initiation of treatment is essential in the management of both high- and low-velocity gunshot wounds so as to decrease the potential morbidity that often follows. Society must also look at the prevalence of these injuries and address the underlying issues that often are the root of the acts of violence.

  15. Application of MD5 Algorithm in Database System%MD5算法在数据库系统中的应用

    Institute of Scientific and Technical Information of China (English)

    罗金涛

    2013-01-01

    数据加密是保护数据安全的重要手段,MD5是目前信息安全领域中使用比较广泛的加密算法,对MD5算法的原理进行了分析,并将MD5算法应用在数据库的登录验证过程中.

  16. Immunization against mucosal disease--bovine viral Diarrhea (MD-BVD) in calves applying lapinized vaccine against swine fever and a modified live virus of MD-BVD.

    Science.gov (United States)

    Haralambiev, H; Tsvetkov, P; Nikolov, A; Gaytandgieva, R

    1975-01-01

    Calves vaccinated with the modified strain C24V react by creating neutralizing antibodies in high titres and are resistent to infection while non-immunized calves manifest the clinical symptoms of MD-BVD. Calves, vaccinated with the lapinized strain "K" of the SF virus react by creating neutralizing antibodies in low titres against the vius of MD-BVD and manifest no apparent clinical symptoms after challenge with the virulent strain MD-BVD.

  17. 76 FR 20034 - Calvin Ramsey, M.D.; Revocation of Registration

    Science.gov (United States)

    2011-04-11

    ... Enforcement Administration Calvin Ramsey, M.D.; Revocation of Registration On December 18, 2009, the Deputy... Show Cause to Calvin Ramsey, M.D. (Respondent), of Millington, Tennessee. The Show Cause Order proposed..., I order that DEA Certificate of Registration, AR7086689, issued to Calvin Ramsey, M.D., be, and...

  18. 76 FR 48884 - Stacey J. Webb, M.D.; Denial of Application

    Science.gov (United States)

    2011-08-09

    .... DEA, 2008 WL 4899525 (6th Cir. 2008). ``Moreover, because `past performance is the best predictor of.... Stodola, M.D., 74 FR 20727 (2009); Dale L. Taylor, M.D., 72 FR 30855 (2007); Andre DeSonia, M.D., 72 FR...

  19. 75 FR 32866 - Special Local Regulations for Marine Events; Patuxent River, Solomons, MD

    Science.gov (United States)

    2010-06-10

    ... River, Solomons, MD AGENCY: Coast Guard, DHS. ACTION: Notice of proposed rulemaking. SUMMARY: The Coast... races, a marine event to be held on the waters of the Patuxent River, near Solomons, MD on October 3... Patuxent River near Solomons, MD. The event consists of offshore power boats racing in a counter-clockwise...

  20. 76 FR 52865 - Special Local Regulations for Marine Events; Patuxent River, Solomons, MD

    Science.gov (United States)

    2011-08-24

    ... River, Solomons, MD AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is... be held on the waters of the Patuxent River, near Solomons, MD on September 24 and 25, 2011. These... Marine Events; Patuxent River, Solomons, MD'' in the Federal Register (76 FR 118). We received no...

  1. 76 FR 35802 - Special Local Regulations for Marine Events; Patuxent River, Solomons, MD

    Science.gov (United States)

    2011-06-20

    .... USCG-2011-0266] RIN 1625-AA08 Special Local Regulations for Marine Events; Patuxent River, Solomons, MD... be held on the waters of the Patuxent River, near Solomons, MD on September 24 and 25, 2011. These... boat races on the Patuxent River near Solomons, MD. The event consists of offshore power boats racing...

  2. 77 FR 47279 - Special Local Regulations for Marine Events, Patuxent River; Solomons, MD

    Science.gov (United States)

    2012-08-08

    ... River; Solomons, MD AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is... be held on the waters of the Patuxent River, near Solomons, MD on September 15 and 16, 2012. These..., Solomons, MD'' in the Federal Register (77 FR 25649). We received no comments on the proposed rule. No...

  3. 75 FR 57388 - Special Local Regulations for Marine Events; Patuxent River, Solomons, MD

    Science.gov (United States)

    2010-09-21

    ... River, Solomons, MD AGENCY: Coast Guard, DHS. ACTION: Temporary final rule. SUMMARY: The Coast Guard is... be held on the waters of the Patuxent River, near Solomons, MD on October 1, 2010 and October 3, 2010... Marine Events; Patuxent River, Solomons, MD'' in the Federal Register (75 FR 32866). Additionally, on...

  4. The Application Research of MD5 Encryption Algorithm in DCT Digital Watermarking

    Science.gov (United States)

    Xijin, Wang; Linxiu, Fan

    This article did the preliminary study of the application of algorithm for MD5 in the digital watermark. It proposed that copyright information will be encrypted using an algorithm MD5, and made rules for the second value image watermarks, through DCT algorithm that embeds an image by the carrier. The extraction algorithms can pick up the watermark and restore MD5 code.

  5. Crystal structure of soluble MD-1 and its interaction with lipid IVa

    Science.gov (United States)

    Yoon, Sung-il; Hong, Minsun; Han, Gye Won; Wilson, Ian A.

    2010-01-01

    Lipopolysaccharide (LPS) of Gram-negative bacteria is a common pathogen-associated molecular pattern (PAMP) that induces potent innate immune responses. The host immune response against LPS is triggered by myeloid differentiation factor 2 (MD-2) in association with Toll-like receptor 4 (TLR4) on the cell surface. The MD-2/TLR4-mediated LPS response is regulated by the evolutionarily related complex of MD-1 and Toll-like receptor homolog RP105. Here, we report crystallographic and biophysical data that demonstrate a previously unidentified direct interaction of MD-1 with LPS. The crystal structure of chicken MD-1 (cMD-1) at 2.0 Å resolution exhibits a β-cup-like fold, similar to MD-2, that encloses a hydrophobic cavity between the two β-sheets. A lipid-like moiety was observed inside the cavity, suggesting the possibility of a direct MD-1/LPS interaction. LPS was subsequently identified as an MD-1 ligand by native gel electrophoresis and gel filtration analyses. The crystal structure of cMD-1 with lipid IVa, an LPS precursor, at 2.4 Å resolution revealed that the lipid inserts into the deep hydrophobic cavity of the β-cup-like structure, but with some important differences compared with MD-2. These findings suggest that soluble MD-1 alone, in addition to its complex with RP105, can regulate host LPS sensitivity. PMID:20534476

  6. MD5算法在用户口令认证中的应用%The Application of MD5 Algorithm in The User Password Authentication

    Institute of Scientific and Technical Information of China (English)

    刘洪民; 印帮辉

    2014-01-01

    MD5算法是目前比较安全且易用的加密算法,其在密码领域有着举足轻重的地位.本文通过介绍MD5算法的特点及加密原理,分析了MD5算法在用户口令认证中的安全隐患,给出了用户口令认证应用中如何提高MD5算法安全性的措施和方法.

  7. Application of MD5 Encryption Algorithm Based on C# Technology%基于C#技术的MD5加密算法的应用

    Institute of Scientific and Technical Information of China (English)

    王倩丽

    2010-01-01

    在对Message-Digest Algorithm 5进行简要描述的同时,对MD5算法的原理作深入分析.运用MD5算法,采用目前流行的C#语言进行了具体研究,设计了MD5加密演示系统,经过测试该系统可以准确实现数据的MD5加密.

  8. SECURITY ANALYSIS ON MD5 AND ITS APPLICATION%MD5安全性分析及其应用

    Institute of Scientific and Technical Information of China (English)

    谭剑鸣; 徐建华; 汪崇华

    2002-01-01

    本文详细论述了MD5报文分解函数对文件签名的工作原理,剖析了MD5的安全性,针对具体的应用提出了使用MD5与RSA结合来解决数字签名的完整方案.文章的最后对MD5在PGP数字签名中的具体应用进行了分析讨论.

  9. Design and Implementation of MD5 with Salt%一种带随机数MD5算法的设计与实现

    Institute of Scientific and Technical Information of China (English)

    张丽香

    2013-01-01

    随着网络的迅速普及,信息加密技术的发展对保障网络安全有着重大的作用与意义.MD5是HASH算法,常用来对重要数据的进行存储,本文对MD5算法进行了简要描述,介绍了MD5的破解方式,并对带随机数MD5算法进行了描述,采用PHP对算法的使用进行实现.

  10. A carbon-rich region in Miller Range 091004 and implications for ureilite petrogenesis

    Science.gov (United States)

    Day, James M. D.; Corder, Christopher A.; Cartigny, Pierre; Steele, Andrew M.; Assayag, Nelly; Rumble, Douglas; Taylor, Lawrence A.

    2017-02-01

    Ureilite meteorites are partially melted asteroidal-peridotite residues, or more rarely, cumulates that can contain greater than three weight percent carbon. Here we describe an exceptional C-rich lithology, composed of 34 modal % large (up to 0.8 mm long) crystalline graphite grains, in the Antarctic ureilite meteorite Miller Range (MIL) 091004. This C-rich lithology is embedded within a silicate region composed dominantly of granular olivine with lesser quantities of low-Ca pyroxene, and minor FeNi metal, high-Ca pyroxene, spinel, schreibersite and troilite. Petrological evidence indicates that the graphite was added after formation of the silicate region and melt depletion. Associated with graphite is localized reduction of host olivine (Fo88-89) to nearly pure forsterite (Fo99), which is associated with FeNi metal grains containing up to 11 wt.% Si. The main silicate region is typical of ureilite composition, with highly siderophile element (HSE) abundances ∼0.3 × chondrite, 187Os/188Os of 0.1260-0.1262 and Δ17O of -0.81 ± 0.16‰. Mineral trace-element analyses reveal that the rare earth elements (REE) and the HSE are controlled by pyroxene and FeNi metal phases in the meteorite, respectively. Modeling of bulk-rock REE and HSE abundances indicates that the main silicate region experienced ∼6% silicate and >50% sulfide melt extraction, which is at the lower end of partial melt removal estimated for ureilites. Miller Range 091004 demonstrates heterogeneous distribution of carbon at centimeter scales and a limited range in Mg/(Mg + Fe) compositions of silicate grain cores, despite significant quantities of carbon. These observations demonstrate that silicate rim reduction was a rapid disequilibrium process, and came after silicate and sulfide melt removal in MIL 091004. The petrography and mineral chemistry of MIL 091004 is permissive of the graphite representing late-stage C-rich melt that pervaded silicates, or carbon that acted as a lubricant during

  11. Miller Early Childhood Sustained Home-visiting (MECSH trial: design, method and sample description

    Directory of Open Access Journals (Sweden)

    Anderson Teresa

    2008-12-01

    Full Text Available Abstract Background Home visiting programs comprising intensive and sustained visits by professionals (usually nurses over the first two years of life show promise in promoting child health and family functioning, and ameliorating disadvantage. Australian evidence of the effectiveness of sustained nurse home visiting in early childhood is limited. This paper describes the method and cohort characteristics of the first Australian study of sustained home visiting commencing antenatally and continuing to child-age two years for at-risk mothers in a disadvantaged community (the Miller Early Childhood Sustained Home-visiting trial. Methods and design Mothers reporting risks for poorer parenting outcomes residing in an area of socioeconomic disadvantage were recruited between February 2003 and March 2005. Mothers randomised to the intervention group received a standardised program of nurse home visiting. Interviews and observations covering child, maternal, family and environmental issues were undertaken with mothers antenatally and at 1, 12 and 24 months postpartum. Standardised tests of child development and maternal-child interaction were undertaken at 18 and 30 months postpartum. Information from hospital and community heath records was also obtained. Discussion A total of 338 women were identified and invited to participate, and 208 were recruited to the study. Rates of active follow-up were 86% at 12 months, 74% at 24 months and 63% at 30 months postpartum. Participation in particular data points ranged from 66% at 1 month to 51% at 24 months postpartum. Rates of active follow-up and data point participation were not significantly different for the intervention or comparison group at any data point. Mothers who presented for antenatal care prior to 20 weeks pregnant, those with household income from full-time employment and those who reported being abused themselves as a child were more likely to be retained in the study. The Miller Early

  12. StandsSIM-MD: a Management Driven forest SIMulator

    Energy Technology Data Exchange (ETDEWEB)

    Barreiro, S.; Rua, J.; Tomé, M.

    2016-07-01

    Aim of the study. The existing stand level forest simulators available in Portugal were not developed with the aim of including up-to-date model versions and were limited in terms of accounting for forest management. The simulators’ platform, sIMfLOR was recently created to implement different growth models with a common philosophy. The objective was developing one easily-updatable, user-friendly, forest management and climate change sensitive simulator capable of projecting growth for the main tree species in Portugal. Area of the study: Portugal. Material and methods: The new simulator was programmed in a modular form consisting of several modules. The growth module integrates different forest growth and yield models (empirical and process-based) for the main wood production tree species in Portugal (eucalypt, umbrella and maritime pines); whereas the management module drives the growth projections along the planning horizon according to a range of forest management approaches and climate (at present only available for eucalypt). Main results: The main result is the StandsSIM-MD Management Driven simulator that overcomes the limitations of the existing stand level simulators. It is a step forward when compared to the models currently available in the sIMfLOR platform covering more tree species, stand structures and stand compositions. It is focused on end-users and it is based on similar concepts regarding the generation of required inputs and generated outputs. Research highlights: Forest Management Driven simulations approach. Multiple Prescriptions-Per-Stand functionality. StandsSIM-MD can be used to support landowners decisions on stand forest management. StandsSIM-MD simulations at regional level can be combined with optimization routines. (Author)

  13. StandsSIM-MD: a Management Driven forest SIMulator

    Directory of Open Access Journals (Sweden)

    Susana Barreiro

    2016-07-01

    Full Text Available Aim of the study: The existing stand level forest simulators available in Portugal were not developed with the aim of including up-to-date model versions and were limited in terms of accounting for forest management. The simulators’ platform, sIMfLOR was recently created to implement different growth models with a common philosophy. The objective was developing one easily-updatable, user-friendly, forest management and climate change sensitive simulator capable of projecting growth for the main tree species in Portugal. Area of the study: Portugal. Material and methods: The new simulator was programmed in a modular form consisting of several modules. The growth module integrates different forest growth and yield models (empirical and process-based for the main wood production tree species in Portugal (eucalypt, umbrella and maritime pines; whereas the management module drives the growth projections along the planning horizon according to a range of forest management approaches and climate (at present only available for eucalypt. Main results: The main result is the StandsSIM-MD Management Driven simulator that overcomes the limitations of the existing stand level simulators. It is a step forward when compared to the models currently available in the sIMfLOR platform covering more tree species, stand structures and stand compositions. It is focused on end-users and it is based on similar concepts regarding the generation of required inputs and generated outputs. Research highlights: -          Forest Management Driven simulations approach -          Multiple Prescriptions-Per-Stand functionality -          StandsSIM-MD can be used to support landowners decisions on stand forest management -          StandsSIM-MD simulations at regional level can be combined with optimization routines Keywords: Forest simulator, Forest Management Approaches; StandsSIM-MD; forest management.

  14. A Secure Hash Function MD-192 With Modified Message Expansion

    CERN Document Server

    Tiwari, Harshvardhan

    2010-01-01

    Cryptographic hash functions play a central role in cryptography. Hash functions were introduced in cryptology to provide message integrity and authentication. MD5, SHA1 and RIPEMD are among the most commonly used message digest algorithm. Recently proposed attacks on well known and widely used hash functions motivate a design of new stronger hash function. In this paper a new approach is presented that produces 192 bit message digest and uses a modified message expansion mechanism which generates more bit difference in each working variable to make the algorithm more secure. This hash function is collision resistant and assures a good compression and preimage resistance.

  15. Nano-scratch study of molecular deposition (MD) films on silicon wafer using nanoindentation~1

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Experiment of the molecular deposition (MD) films with and without alkyl terminal de-posited on the silicon wafer were conducted by using nanoindentation. It was found that MD filmsand alkyl terminated MD films exhibit higher critical load (scratch resistance or adhesive strength)and lower coefficient of friction compared with the silicon substrate. Critical load (scratch resis-tance) increases with the number of layers, and coefficients of friction of those MD film with alkylterminal are still best for the same layer of MD film.

  16. 改进MD5码增强网站密码安全性

    Institute of Scientific and Technical Information of China (English)

    张越; 陈跃; 刘林飞

    2009-01-01

    目的探讨改进MD5码,增强网络安全性.方法采用对用户密码进行加长、加强的二次加密,并对MD5码的算法进行修改,再使用MD5二次加密或多次加密.结果通过改进MD5码,用户密码安全性明显增强.结论改进MD5码,可以提高网站安全性.

  17. Pragmatic Analyses of Martin Luther King (Jr)'s Speech: "I Have a Dream"--An Introspective Prognosis

    Science.gov (United States)

    Josiah, Ubong E.; Oghenerho, Gift

    2015-01-01

    This paper investigates the speech of Martin Luther King (Jr.) titled: "I Have a Dream", presented in 1963 at the Lincoln Memorial. This speech is selected for use because it involves a speaker and an audience who belong to a particular speech community. The speech is about the failed promises by the Americans whose dream advocate…

  18. Crystallization and preliminary X-ray crystallographic analysis of polyphenol oxidase from Juglans regia (jrPPO1)

    Energy Technology Data Exchange (ETDEWEB)

    Zekiri, Florime; Bijelic, Aleksandar; Molitor, Christian; Rompel, Annette, E-mail: annette.rompel@univie.ac.at [Universität Wien, Althanstrasse 14, 1090 Wien (Austria)

    2014-05-28

    The crystallization and preliminary X-ray crystallographic analysis of a plant PPO exhibiting monophenolase activity from J. regia (jrPPO1) in its active form (Asp{sup 101}–Arg{sup 445}) are reported. Tyrosinase is a type 3 copper enzyme that catalyzes the ortho-hydroxylation of monophenols to diphenols as well as their subsequent oxidation to quinones, which are precursors for the biosynthesis of melanins. The first plant tyrosinase from walnut leaves (Juglans regia) was purified to homogeneity and crystallized. During the purification, two forms of the enzyme differing only in their C-termini [jrPPO1(Asp{sup 101}–Pro{sup 444}) and jrPPO1(Asp{sup 101}–Arg{sup 445})] were obtained. The most abundant form jrPPO1(Asp{sup 101}–Arg{sup 445}), as described in Zekiri et al. [Phytochemistry (2014 ▶), 101, 5–15], was crystallized, resulting in crystals that belonged to space group C121, with unit-cell parameters a = 115.56, b = 91.90, c = 86.87 Å, α = 90, β = 130.186, γ = 90°, and diffracted to 2.39 Å resolution. Crystals were only obtained from solutions containing at least 30% polyethylene glycol 5000 monomethyl ether in a close-to-neutral pH range.

  19. "God and Man at Yale" and beyond: The Thoughts of William F. Buckley, Jr. on Higher Education, 1949-1955

    Science.gov (United States)

    Green, James

    2012-01-01

    The March 24, 2008, edition of "National Review" (NR) was dedicated to the memory of its founder: William F. Buckley, Jr., who had passed away on February 27, 2008. It included thirty two different memorials about him written by prominent authors, editors, social commentators, fellow journalists, politicians, and historians. Then NR…

  20. Health Care Fraud: Characteristics, Sanctions, and Prevention. Briefing Report to the Honorable William V. Roth, Jr., U.S. Senate.

    Science.gov (United States)

    General Accounting Office, Washington, DC. Accounting and Financial Management Div.

    At the request of Senator William Roth, Jr., the General Accounting Office (GAO) reviewed Medicare and Medicaid fraud investigations that agency inspectors general referred to the Department of Justice for prosecution to identify characteristics of alleged fraud against the government and to determine actions taken against those caught defrauding…

  1. The Limits of Master Narratives in History Textbooks: An Analysis of Representations of Martin Luther King, Jr.

    Science.gov (United States)

    Alridge, Derrick P.

    2006-01-01

    In this study, I argue that American history textbooks present discrete, heroic, one-dimensional, and neatly packaged master narratives that deny students a complex, realistic, and rich understanding of people and events in American history. In making this argument, I examine the master narratives of Martin Luther King, Jr., in high school history…

  2. Toward a Modern Synthesis of Immunity: Charles A. Janeway Jr. and the Immunologist’s Dirty Little Secret

    Science.gov (United States)

    Gayed, Peter M.

    2011-01-01

    This essay chronicles the major theoretical and experimental contributions made by Charles A. Janeway, Jr. (1943-2003), Howard Hughes Medical Institute investigator and Yale Professor of Immunobiology, who established the fundamental role of the innate immune system in the induction of the adaptive arm. PMID:21698045

  3. Toward a Modern Synthesis of Immunity: Charles A. Janeway Jr. and the Immunologist’s Dirty Little Secret

    OpenAIRE

    Gayed, Peter M.

    2011-01-01

    This essay chronicles the major theoretical and experimental contributions made by Charles A. Janeway, Jr. (1943-2003), Howard Hughes Medical Institute investigator and Yale Professor of Immunobiology, who established the fundamental role of the innate immune system in the induction of the adaptive arm.

  4. Fetal and neonatal anemia associated with anti-Jr(a) : a case report showing a poorly hemolytic mechanism.

    Science.gov (United States)

    Sasamoto, Naoko; Tomimatsu, Takuji; Nagamine, Keisuke; Oshida, Machiko; Kashiwagi, Hirokazu; Koyama, Shinsuke; Kanagawa, Takeshi; Arahori, Hitomi; Tomiyama, Yoshiaki; Kimura, Tadashi

    2011-08-01

    Although recently published case reports suggest the significance of Jr(a) alloimmunization in the obstetric setting, the involved mechanism still remains unclear. Here we report a case of severe fetal and neonatal anemia associated with anti-Jr(a) alloimmunization, which was successfully managed using Doppler assessment of peak systolic velocity of the fetal middle cerebral artery (MCA-PSV). A Japanese woman with anti-Jr(a) (titer 1024) was referred to our department at 20 weeks' gestation. As fetal MCA-PSV exceeded 1.5 multiple of median, labor was induced and a female neonate of 1998 g was delivered vaginally at 33 weeks and 5 days of gestation. The infant's hematocrit and hemoglobin levels were 25.4% and 82 g/L, respectively, but her total bilirubin level (15 µmol/L; 0.9 mg/dL) and reticulocyte counts (4.5%) were low. During the course, the infant showed no apparent signs of hemolysis. Jr(a) alloimmunization should be recognized as a possible cause of fetal anemia with no direct hemolytic process. © 2011 The Authors. Journal of Obstetrics and Gynaecology Research © 2011 Japan Society of Obstetrics and Gynecology.

  5. Human Progress Never Rolls in on Wheels of Inevitability: Biographies of Martin Luther King, Jr., in the Classroom.

    Science.gov (United States)

    Kazemek, Francis E.

    1990-01-01

    Presents resources for teaching about Dr. Martin Luther King, Jr. Outlines criteria for selecting biographies for children and young adults. Identifies problems in certain biographies of King, and recommends high quality biographies of King. Discusses exercises for integrating themes from King's life into the classroom. (RW)

  6. Pretext, Context, Subtext: Textual Power in the Writing of Langston Hughes, Richard Wright, and Martin Luther King, Jr.

    Science.gov (United States)

    Bogumil, Mary L.; Molino, Michael R.

    1990-01-01

    Studies verbal pretexts, social subtexts, and interpretive contexts of works by Langston Hughes, Richard Wright, and Martin Luther King, Jr. Notes that cultural repression is propagated (and dispelled) in part through the power of language. Notes that these texts are relevant for teaching textual power in hopes of affecting social change. (RS)

  7. "... because I'm Batman" : En undersökning av maskulinitet i Frank Millers Batman: The Dark Knight Returns

    OpenAIRE

    Nilsson, Kristina

    2015-01-01

    I detta arbete kommer jag att undersöka hur maskulinitet gestaltas i Frank Millers Batman: The Dark Knight Returns. Det jag vill fokusera på är de olika maskulina drag som går att urskilja i serien. Warner Bros. Animation gav 2012 ut den första delen av en animerad filmatisering av Millers Batman-serie, som senare följdes av den andra och avslutande delen 2013. I min undersökning kommer jag även att ta hjälp av de båda animeringarna för att se på vilka sätt maskuliniteten gestaltas hos de oli...

  8. Karyological investigations and new chromosome number reports in Bellevalia Lapeyrouse, 1808 and Muscari Miller, 1758 (Asparagaceae) from Algeria

    Science.gov (United States)

    Azizi, Nadjat; Amirouche, Rachid; Amirouche, Nabila

    2016-01-01

    Abstract Karyological investigations were carried out on four species of Bellevalia Lapeyrouse, 1808 and Muscari Miller, 1758 (Asparagaceae) sampled in contrasting bioclimatic conditions of Algeria. The endemic Bellevalia mauritanica Pomel, 1874 was found to have a tetraploid cytotype 2n = 4x = 16 and an octoploid 2n = 8x = 32 which is a new report. The chromosome number 2n = 2x = 18 in Muscari comosum (Linnaeus, 1753) Miller, 1768 and Muscari maritimum Desfontaines, 1798 was in conformity with earlier reports. The latter species reveals a lesser bimodality of the karyotype. Within Muscari neglectum Gussone ex Tenore, 1842 pentaploid (2n = 5x = 45), hexaploid (2n = 6x = 54) and very rare octoploid cytotype (2n = 8x = 72) have been reported in Algeria. Principal component analysis performed on basis of karyotype parameters, showed a segregation of the different cytotypes. This study provides new karyological information, which is discussed in a taxonomic context. PMID:27186346

  9. MANEJO DE CORTE DAS FOLHAS DE Copernicia prunifera (Miller H. E. Moore NO PIAUÍ

    Directory of Open Access Journals (Sweden)

    CLEMILTON DA SILVA FERREIRA

    2013-01-01

    Full Text Available The carnauba (Copernicia prunifera (Miller HE Moore is a native fruit species to the north- east of Brazil and its exploration is based mainly on the extract of wax powder from leaves. The objective of this study was to evaluate the effect of different management strategies of cutting leaves, developmental stages and leaf age on leaf traits and physical-chemical attributes of carnauba wax in a natural population of carnauba palm located at the Cajazeira Farm, municipality of União, Piauí state, Brazil. The selected plants were identi- fied and classified in two developmental stages: capoteiro and adult palm. The management strategies cutting leaves were: one cut in August; two cuts, the first in August and the second in December; and one cut in De- cember. The leaves were separated according to age into new and old leaf. It was performed the individual analysis of variance of leaf number (LN, wax powder production (WP, ratio WP/LN, moisture content, impu- rities content and wax yield for each management systems as well as the analysis of the different managements. Leaf age presented as the attribute of greater relevance in the commercial use of carnauba. The best manage- ment strategy for cutting leaves of carnauba consists of a single annual cut in December.

  10. On the Miller-Tucker-Zemlin Based Formulations for the Distance Constrained Vehicle Routing Problems

    Science.gov (United States)

    Kara, Imdat

    2010-11-01

    Vehicle Routing Problem (VRP), is an extension of the well known Traveling Salesman Problem (TSP) and has many practical applications in the fields of distribution and logistics. When the VRP consists of distance based constraints it is called Distance Constrained Vehicle Routing Problem (DVRP). However, the literature addressing on the DVRP is scarce. In this paper, existing two-indexed integer programming formulations, having Miller-Tucker-Zemlin based subtour elimination constraints, are reviewed. Existing formulations are simplified and obtained formulation is presented as formulation F1. It is shown that, the distance bounding constraints of the formulation F1, may not generate the distance traveled up to the related node. To do this, we redefine the auxiliary variables of the formulation and propose second formulation F2 with new and easy to use distance bounding constraints. Adaptation of the second formulation to the cases where new restrictions such as minimal distance traveled by each vehicle or other objectives such as minimizing the longest distance traveled is discussed.

  11. Amino acids generated from hydrated Titan tholins: Comparison with Miller-Urey electric discharge products

    Science.gov (United States)

    Cleaves, H. James; Neish, Catherine; Callahan, Michael P.; Parker, Eric; Fernández, Facundo M.; Dworkin, Jason P.

    2014-07-01

    Various analogues of Titan haze particles (termed ‘tholins’) have been made in the laboratory. In certain geologic environments on Titan, these haze particles may come into contact with aqueous ammonia (NH3) solutions, hydrolyzing them into molecules of astrobiological interest. A Titan tholin analogue hydrolyzed in aqueous NH3 at room temperature for 2.5 years was analyzed for amino acids using highly sensitive ultra-high performance liquid chromatography coupled with fluorescence detection and time-of-flight mass spectrometry (UHPLC-FD/ToF-MS) analysis after derivatization with a fluorescent tag. We compare here the amino acids produced from this reaction sequence with those generated from room temperature Miller-Urey (MU) type electric discharge reactions. We find that most of the amino acids detected in low temperature MU CH4/N2/H2O electric discharge reactions are generated in Titan simulation reactions, as well as in previous simulations of Triton chemistry. This argues that many processes provide very similar mixtures of amino acids, and possibly other types of organic compounds, in disparate environments, regardless of the order of hydration. Although it is unknown how life began, it is likely that given reducing conditions, similar materials were available throughout the early Solar System and throughout the universe to facilitate chemical evolution.

  12. Miller-Urey Spark-Discharge Experiments in the Deuterium World.

    Science.gov (United States)

    Cooper, Geoffrey J T; Surman, Andrew J; McIver, Jim; Colón-Santos, Stephanie M; Gromski, Piotr S; Buchwald, Saskia; Suárez Marina, Irene; Cronin, Leroy

    2017-07-03

    We designed and conducted a series of primordial-soup Miller-Urey style experiments with deuterated gases and reagents to compare the spark-discharge products of a "deuterated world" with the standard reaction in the "hydrogenated world". While the deuteration of the system has little effect on the distribution of amino acid products, significant differences are seen in other regions of the product-space. Not only do we observe about 120 new species, we also see significant differences in their distribution if the two hydrogen isotope worlds are compared. Several isotopologue matches can be identified in both, but a large proportion of products have no equivalent in the corresponding isotope world with ca. 43 new species in the D world and ca. 39 new species in the H world. This shows that isotopic exchange (the addition of only one neutron) may lead to significant additional complexity in chemical space under otherwise identical reaction conditions. © 2017 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

  13. Miller-Urey spark-discharge experiments in the deuterium world

    Energy Technology Data Exchange (ETDEWEB)

    Cooper, Geoffrey J.T.; Surman, Andrew J.; McIver, Jim; Colon-Santos, Stephanie M.; Gromski, Piotr S.; Buchwald, Saskia; Suarez Marina, Irene; Cronin, Leroy [WestCHEM, School of Chemistry, University of Glasgow (United Kingdom)

    2017-07-03

    We designed and conducted a series of primordial-soup Miller-Urey style experiments with deuterated gases and reagents to compare the spark-discharge products of a ''deuterated world'' with the standard reaction in the ''hydrogenated world''. While the deuteration of the system has little effect on the distribution of amino acid products, significant differences are seen in other regions of the product-space. Not only do we observe about 120 new species, we also see significant differences in their distribution if the two hydrogen isotope worlds are compared. Several isotopologue matches can be identified in both, but a large proportion of products have no equivalent in the corresponding isotope world with ca. 43 new species in the D world and ca. 39 new species in the H world. This shows that isotopic exchange (the addition of only one neutron) may lead to significant additional complexity in chemical space under otherwise identical reaction conditions. (copyright 2017 The Authors. Published by Wiley-VCH Verlag GmbH and Co. KGaA.)

  14. Antibacterial activity of endophytic fungi from leaves of Indigofera suffruticosa Miller (Fabaceae)

    Science.gov (United States)

    dos Santos, Irailton Prazeres; da Silva, Luís Cláudio Nascimento; da Silva, Márcia Vanusa; de Araújo, Janete Magali; Cavalcanti, Marilene da Silva; Lima, Vera Lucia de Menezes

    2015-01-01

    Endophytic fungi were isolated from healthy leaves of Indigofera suffruticosa Miller, a medicinal plant found in Brazil which is used in folk medicine to treat various diseases. Among 65 endophytic fungi isolated, 18 fungi showed activity against at least one tested microorganism in preliminary screening, and the best results were obtained with Nigrospora sphaerica (URM-6060) and Pestalotiopsis maculans (URM-6061). After fermentation in liquid media and in semisolid media, only N. sphaerica demonstrated antibacterial activity (in Potato Dextrose Broth-PDB and in semisolid rice culture medium). In the next step, a methanolic extract from rice culture medium (NsME) and an ethyl acetate extract (NsEAE) from the supernatant of PDB were prepared and both exhibited antimicrobial activity against Gram-negative and Gram-positive bacteria. The best result was observed against Staphylococcus aureus, with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of 1.56 mg/mL and 6.25 mg/mL, respectively, for NsME and MIC and MBC values of 0.39 mg/mL and 3.12 mg/mL, respectively, for NsEAE. This study is the first report about the antimicrobial activity of endophytic fungi residing in I. suffruticosa leaves, in which the fungus N. sphaerica demonstrated the ability to produce bioactive agents with pharmaceutical potential, and may provide a new lead in the pursuit of new biological sources of drug candidates. PMID:25999918

  15. Enhanced Synthesis of Alkyl Amino Acids in Miller's 1958 H2S Experiment

    Science.gov (United States)

    Parker, Eric T.; Cleaves, H. James; Callahan, Michael P.; Dworkin, James P.; Glavin, Daniel P.; Lazcano, Antonio; Bada, Jeffrey L.

    2011-01-01

    Stanley Miller's 1958 H2S-containing experiment, which included a simulated prebiotic atmosphere of methane (CH4), ammonia (NH3), carbon dioxide (CO2), and hydrogen sulfide (H2S) produced several alkyl amino acids, including the alpha-, beta-, and gamma-isomers of aminobutyric acid (ABA) in greater relative yields than had previously been reported from his spark discharge experiments. In the presence of H2S, aspariic and glutamic acids could yield alkyl amino acids via the formation of thioimide intermediates. Radical chemistry initiated by passing H2S through a spark discharge could have also enhanced alkyl amino acid synthesis by generating alkyl radicals that can help form the aldehyde and ketone precursors to these amino acids. We propose mechanisms that may have influenced the synthesis of certain amino acids in localized environments rich in H2S and lightning discharges, similar to conditions near volcanic systems on the early Earth, thus contributing to the prebiotic chemical inventory of the primordial Earth.

  16. Evaluation of respiratory effects in miners and millers exposed to talc free of asbestos and silica.

    Science.gov (United States)

    Wegman, D H; Peters, J M; Boundy, M G; Smith, T J

    1982-08-01

    Miners and millers of talc ore, free from asbestos and silica, were examined for respiratory effects. A study of 116 subjects included the modified British Medical Research Council respiratory symptom questionnaire, simple spirometry, chest radiography, and limited examination of the chest. A one-year follow-up evaluation was performed on 103 subjects. Of the 12 subjects whose chest radiographs showed small round or irregular opacities (perfusion 1/0 or greater), five had never smoked cigarettes. Pulmonary function values at the time of the initial study were less than predicted and the rates of loss of FEV1 and FVC greater than expected. These differences were in part attributed to cigarette smoking but were greater than predicted from that source alone. There was evidence of an exposure effect after adjusting for cigarette smoking and we conclude that these workers have been affected by their exposures. No clear interaction between smoking and exposure could be identified. Populations such as this will need to be studied for longer periods to determine what current dust levels are safe.

  17. Miller Fisher Syndrome: A Case Report Highlighting Heterogeneity of Clinical Features and Focused Differential Diagnosis.

    Science.gov (United States)

    Yepishin, Ilya V; Allison, Randall Z; Kaminskas, David A; Zagorski, Natalia M; Liow, Kore K

    2016-07-01

    Miller Fisher Syndrome (MFS) is a rare variant of Guillain-Barré Syndrome (GBS) that has a geographically variable incidence. It is largely a clinical diagnosis based on the cardinal clinical features of ataxia, areflexia, and opthalmoplegia, however, other neurological signs and symptoms may also be present. Serological confirmation with the anti-GQ1b antibody is available and allows for greater diagnostic certainty in the face of confounding symptoms. A self-limiting course is typical of MFS. The following case report is that of a patient who presented with generalized weakness, somatic pain, inability to walk, and diplopia following an upper respiratory illness. The patient exhibited the classic triad of ataxia, areflexia, and opthalmoplegia characteristic of MFS, but also had less typical signs and symptoms making for a more challenging diagnostic workup. Our suspected diagnosis of MFS was serologically confirmed with positive anti-GQ1b antibody titer and the patient was successfully treated with Intravenous immune globulin (IVIG).

  18. Pavlov's position toward Konorski and Miller's distinction between Pavlovian and motor conditioning paradigms.

    Science.gov (United States)

    Windholz, G; Wyrwicka, W

    1996-01-01

    Two Warsaw medical students, Jerzy Konorski and Stefan Miller, having read I.P. Pavlov's works on conditional reflexes, informed him in a 1928 letter that they had discovered a new type of conditioning. A previously neutral stimulus preceded the passive lifting of a dog's paw which then was followed by feeding; this stimulus then evoked the spontaneous raising of that paw. Pavlov responded informing them that their conditioning of motor responses expanded his theory of higher nervous activity, but that their conditioning paradigm-that they named CRII-did not differ fundamentally from the Pavlovian conditioning paradigm. The replication of the Warsaw experiment in Pavlov's laboratory failed to provide unequivocal results. From 1931 to 1933, Konorski, working in Pavlov's Leningrad laboratory, further explored the parameters of CRII. Pavlov insisted that the conditioning of motor movements differs from the conditioning of other sensory analyzers only in that, on the neural level, the motor analyzer is both afferent, that is, perceptive, and efferent, that is, responsive. Konorski was not convinced, and he subsequently maintained that the two conditioning paradigms were fundamentally different.

  19. Atomic and electronic structure of molybdenum carbide phases: bulk and low Miller-index surfaces.

    Science.gov (United States)

    Politi, José Roberto dos Santos; Viñes, Francesc; Rodriguez, Jose A; Illas, Francesc

    2013-08-14

    The geometric and electronic structure of catalytically relevant molybdenum carbide phases (cubic δ-MoC, hexagonal α-MoC, and orthorhombic β-Mo2C) and their low Miller-index surfaces have been investigated by means of periodic density functional theory (DFT) based calculations with the Perdew-Burke-Ernzerhof (PBE) exchange-correlation functional. Comparison to available experimental data indicates that this functional is particularly well suited to study these materials. The calculations reveal that β-Mo2C has a stronger metallic character than the other two polymorphs, both β-Mo2C and δ-MoC have a large ionic contribution, and δ- and α-MoC exhibit the strongest covalent character. Among the various surfaces explored, the calculations reveal the high stability of the δ-MoC(001) nonpolar surface, Mo- and C-terminated (001) polar surfaces of α-MoC, and the nonpolar (011) surface of β-Mo2C. A substantially low work function of only 3.4 eV is predicted for β-Mo2C(011), suggesting that this system is particularly well suited for (electro)catalytic processes where surface → adsorbate electron transfer is essential. The overall implications for heterogeneously catalysed reactions by these molybdenum carbide nanoparticles are also discussed.

  20. Enhanced Synthesis of Alkyl Amino Acids in Miller's 1958 H2S Experiment

    Science.gov (United States)

    Parker, Eric T.; Cleaves, H. James; Callahan, Michael P.; Dworkin, James P.; Glavin, Daniel P.; Lazcano, Antonio; Bada, Jeffrey L.

    2011-01-01

    Stanley Miller's 1958 H2S-containing experiment, which included a simulated prebiotic atmosphere of methane (CH4), ammonia (NH3), carbon dioxide (CO2), and hydrogen sulfide (H2S) produced several alkyl amino acids, including the alpha-, beta-, and gamma-isomers of aminobutyric acid (ABA) in greater relative yields than had previously been reported from his spark discharge experiments. In the presence of H2S, aspariic and glutamic acids could yield alkyl amino acids via the formation of thioimide intermediates. Radical chemistry initiated by passing H2S through a spark discharge could have also enhanced alkyl amino acid synthesis by generating alkyl radicals that can help form the aldehyde and ketone precursors to these amino acids. We propose mechanisms that may have influenced the synthesis of certain amino acids in localized environments rich in H2S and lightning discharges, similar to conditions near volcanic systems on the early Earth, thus contributing to the prebiotic chemical inventory of the primordial Earth.

  1. Amino Acids Generated from Hydrated Titan Tholins: Comparison with Miller-Urey Electric Discharge Products

    Science.gov (United States)

    Cleaves, H. James, II; Neish, Catherine; Callahan, Michael P.; Parker, Eric; Fernandez, Facundo M.; Dworkin, Jason P.

    2014-01-01

    Various analogues of Titan haze particles (termed tholins) have been made in the laboratory. In certain geologic environments on Titan, these haze particles may come into contact with aqueous ammonia (NH3) solutions, hydrolyzing them into molecules of astrobiological interest. A Titan tholin analogue hydrolyzed in aqueous NH3 at room temperature for 2.5 years was analyzed for amino acids using highly sensitive ultra-high performance liquid chromatography coupled with fluorescence detection and time-of-flight mass spectrometry (UHPLC-FDToF-MS) analysis after derivatization with a fluorescent tag. We compare here the amino acids produced from this reaction sequence with those generated from room temperature Miller-Urey (MU) type electric discharge reactions. We find that most of the amino acids detected in low temperature MU CH4N2H2O electric discharge reactions are generated in Titan simulation reactions, as well as in previous simulations of Triton chemistry. This argues that many processes provide very similar mixtures of amino acids, and possibly other types of organic compounds, in disparate environments, regardless of the order of hydration. Although it is unknown how life began, it is likely that given reducing conditions, similar materials were available throughout the early Solar System and throughout the universe to facilitate chemical evolution.

  2. Review of The Chicago Guide to Writing about Numbers by Jane E. Miller

    Directory of Open Access Journals (Sweden)

    Neil Lutsky

    2009-01-01

    Full Text Available Miller, J. E. 2004. The Chicago Guide to Writing about Numbers. Chicago, IL: University of Chicago Press. 304 pp. Cloth $45 ISBN: 9780226526300, Softcover $17. ISBN: 9780226526317.The Chicago Guide to Writing about Numbers is a reference work suitable for anyone interested in understanding, using, or promoting quantitative thinking. Its primary aim is to identify and illustrate ways in which information associated with numbers can be conveyed most effectively given a particular communication purpose and context. The book is directed at writers who incorporate numbers in verbal or visual displays in documents, in oral presentations, or on the Web. The Chicago Guide to Writing about Numbers identifies overarching principles, offers concrete advice, and presents illuminating examples and models. The book can be used for instructional purposes for undergraduates, and a means of doing so is described. The review concludes by considering the book’s contributions to a wider call to help citizens write or argue more effectively by using numbers.

  3. Topical Aloe Vera (Aloe barbadensis Miller) Extract Does Not Accelerate the Oral Wound Healing in Rats.

    Science.gov (United States)

    Coelho, Fernanda Hack; Salvadori, Gabriela; Rados, Pantelis Varvaki; Magnusson, Alessandra; Danilevicz, Chris Krebs; Meurer, Luise; Martins, Manoela Domingues

    2015-07-01

    The effect of topical application of Aloe Vera (Aloe barbadensis Miller) extract was assessed on the healing of rat oral wounds in an in vivo model using 72 male Wistar rats divided into three groups (n = 24): control, placebo and Aloe Vera (0.5% extract hydroalcoholic). Traumatic ulcers were caused in the dorsum of the tongue using a 3-mm punch tool. The Aloe Vera and placebo group received two daily applications. The animals were sacrificed after 1, 5, 10 and 14 days. Clinical analysis (ulcer area and percentage of repair) and histopathological analysis (degree of re-epithelialization and inflammation) were performed. The comparison of the differences between scores based on group and experimental period, both in quantitative and semi-quantitative analyses, was performed using the Kruskal-Wallis test. The significance level was 5%. On day 1, all groups showed predominantly acute inflammatory infiltrate. On day 5, there was partial epithelialization and chronic inflammatory infiltrate. On the days 10 and 14 total repair of ulcers was observed. There was no significant difference between groups in the repair of mouth ulcers. It is concluded that treatment using Aloe Vera as an herbal formulation did not accelerate oral wound healing in rats.

  4. Comparative evaluation of the effect of chlorhexidine and Aloe barbadensis Miller (Aloe vera) on dentin stabilization using shear bond testing

    OpenAIRE

    Dakshita Joy Sinha; Natasha Jaiswal; Agrima Vasudeva; Paridhi Garg; Shashi Prabha Tyagi; Priyanka Chandra

    2016-01-01

    Introduction: The main objective of adhesive dentistry is to create an effective, durable union between the tooth structure and restorative material. However, degradation of adhesive dentine interface remains largely responsible for the relatively short lifetime of tooth colored resin restoration. Aim: The aim of the study is to compare the dentin collagen stabilization property of Chlorhexidine (CHX) and Aloe barbadensis Miller using shear bond strength testing. Materials and Methods: ...

  5. Direct comparasion of an engine working under Otto, Miller end Diesel cycles : thermodynamic analysis and real engine performance

    OpenAIRE

    Ribeiro, Bernardo Sousa; Martins, Jorge

    2007-01-01

    One of the ways to improve thermodynamic efficiency of Spark Ignition engines is by the optimisation of valve timing and lift and compression ratio. The throttleless engine and the Miller cycle engine are proven concepts for efficiency improvements of such engines. This paper reports on an engine with variable valve timing (VVT) and variable compression ratio (VCR) in order to fulfill such an enhancement of efficiency. Engine load is controlled by the valve opening per...

  6. 散列算法MD5和SHA-1的比较%Comparison between MD5 and SHA-1

    Institute of Scientific and Technical Information of China (English)

    王泽; 曹莉莎

    2016-01-01

    MD5 and SHA-1 are the two known Hash Algorithm which are widely applied in information security, they are both developed from MD4.This paper introduces their algorithm logic in detail, compares them though simulation experiment ,soft-ware testing, etc. Finally, it draw a conclusion:The SHA-1 algorithm is more secure than the MD5 algorithm, but in the same hardware, SHA-1 is slower than MD5.%MD5和SHA-1是两个已知的广泛应用于信息安全的散列算法,均由MD4发展而来。详细介绍了它们的算法逻辑,并通过模拟实验、软件测试等方式对其在各个方面进行比较,最终得出结论:SHA-1算法比MD5算法的安全性更高,但在同一硬件上,SHA-1比MD5运行的要慢。

  7. MD1878: Operation with primary collimators at tighter settings

    CERN Document Server

    Mirarchi, Daniele; Biancacci, Nicolo; Bruce, Roderik; Buffat, Xavier; Carver, Lee Robert; Fiascaris, Maria; Mereghetti, Alessio; Redaelli, Stefano; Rossi, Roberto; Salvachua Ferrando, Belen Maria; Soderen, Martin; Trad, Georges

    2017-01-01

    Primary (TCP) collimators of the betatron cleaning insertion determine the betatron cut of the LHC beam. During the 2016 they were set at 5.5 nominal beam sigmas at 6.5 TeV (i.e. by using a normalized emittance " = 3:5 m is used). Reducing their settings is a possible way to push the at the LHC, which depends on the collimation hierarchy. This study aims at understanding possible limitations of operating the LHC with tighter settings of the primary collimators. This is a crucial input to the choice of operational conguration in terms of at the LHC as well as at the HL-LHC. This study follows a successful MD done in block 3 to understand limitations from TCP impedance [1]. The outcome of this MD can also have an impact for the design of the FCC collimation system, which is currently based on the present TCP gaps. Studies of beam stability as a function of octupole current, transverse feedback gain (ADT) and transverse separation at the IPs were also carried out.

  8. MD modeling of defects in Fe and their interactions

    Science.gov (United States)

    Marian, Jaime; Wirth, Brian D.; Schäublin, Robin; Odette, G. R.; Perlado, J. Manuel

    2003-12-01

    Ferritic/martensitic steels considered as candidate first-wall materials for fusion reactors experience significant radiation hardening at temperatures below ˜400 °C. A number of experimental studies in ferritic alloys, performed at higher temperatures, have shown the existence of large interstitial loops with Burgers vector {1}/{2} and in the bulk, which may provide a significant contribution to the hardening caused during irradiation at lower temperatures. Hardening arises from a high number density of loops, voids and small precipitates, which pin system dislocations, impeding their free glide. In this work, we review the nature of the different interstitial dislocation loops observed in α-Fe and ferritic materials, assess the effect of substitutional impurities on migrating {1}/{2} clusters, and apply atomistic modeling to investigate the mechanisms of formation and growth of loops from smaller cascade-produced {1}/{2} clusters. The proposed mechanism reconciles experimental observations with continuum elasticity theory and recent MD modeling of defect production in displacement cascades. In addition, the interaction of screw dislocations, known to control the low-temperature plastic response of b.c.c. materials to external stress, with dislocation loops is investigated with MD, where the main physical mechanisms are identified, cutting angles estimated and a first-order estimation of the induced hardening is provided.

  9. Methanol adsorption studies of electrified ACF by MD simulations

    Institute of Scientific and Technical Information of China (English)

    LIANG Shiqiang; XU Jingzhong

    2004-01-01

    In order to clarify whether static electricity can impose a control on physical adsorption of polar adsorbates, MD simulations were carried out to study the adsorption/desorption behavior of methanol in the nanopores of electrified activated carbon fiber (ACF). Some special phenomena were observed from the MD simulations for methanol adsorption in a mesopore of electrified ACF. For example it takes a shorter time for the adsorbates to reach the adsorption sites on the mesopore wall, the liquid-like methanol is highly condensed, the methanol molecules have a unique distribution of space orientation, and the total energy of equilibrium state dropped a lot. These phenomena indicate the static electricity reinforced the interaction between the polar methanol and the electrified ACF, so that the intensity, stability and regularity of adsorption were increased, and thus we predict that the adsorption capacity will be increased and the adsorption process will be accelerated. When adsorption equilibrium was reached at room temperature, eliminated the electric charges and heated the system, the desorption tendency was evidently observed from our simulations at 60℃ or so.

  10. MD1878: Operation with primary collimators at tighter settings

    CERN Document Server

    Mirarchi, Daniele; Biancacci, Nicolo; Bruce, Roderik; Buffat, Xavier; Carver, Lee Robert; Fiascaris, Maria; Mereghetti, Alessio; Redaelli, Stefano; Rossi, Roberto; Salvachua Ferrando, Belen Maria; Soderen, Martin; Trad, Georges; CERN. Geneva. ATS Department

    2017-01-01

    Primary (TCP) collimators of the betatron cleaning insertion determine the betatron cut of the LHC beam. During the 2016 they were set at 5.5 nominal beam sigmas at 6.5 TeV (i.e. by using a normalized emittance ε* = 3:5 μm is used). Reducing their settings is a possible way to push the ß* at the LHC, which depends on the collimation hierarchy. This study aims at understanding possible limitations of operating the LHC with tighter settings of the primary collimators. This is a crucial input to the choice of operational configuration in terms of ß* at the LHC as well as at the HL-LHC. This study follows a successful MD done in block 3 to understand limitations from TCP impedance [1]. The outcome of this MD can also have an impact for the design of the FCC collimation system, which is currently based on the present TCP gaps. Studies of beam stability as a function of octupole current, transverse feedback gain (ADT) and transverse separation at the IPs were also carried out.

  11. Guillain-Barré syndrome- and Miller Fisher syndrome-associated Campylobacter jejuni lipopolysaccharides induce anti-GM1 and anti-GQ1b Antibodies in rabbits.

    NARCIS (Netherlands)

    M.A. de Klerk; H.P. Endtz (Hubert); B.C. Jacobs (Bart); J.D. Laman (Jon); F.G.A. van der Meché (Frans); P.A. van Doorn (Pieter); C.W. Ang (Wim)

    2001-01-01

    textabstractCampylobacter jejuni infections are thought to induce antiganglioside antibodies in patients with Guillain-Barre syndrome (GBS) and Miller Fisher syndrome (MFS) by molecular mimicry between C. jejuni lipopolysaccharides (LPS) and gangliosides. We used purifi

  12. Guillain-Barré syndrome- and Miller Fisher syndrome-associated Campylobacter jejuni lipopolysaccharides induce anti-GM1 and anti-GQ1b Antibodies in rabbits.

    NARCIS (Netherlands)

    M.A. de Klerk; H.P. Endtz (Hubert); B.C. Jacobs (Bart); J.D. Laman (Jon); F.G.A. van der Meché (Frans); P.A. van Doorn (Pieter); C.W. Ang (Wim)

    2001-01-01

    textabstractCampylobacter jejuni infections are thought to induce antiganglioside antibodies in patients with Guillain-Barre syndrome (GBS) and Miller Fisher syndrome (MFS) by molecular mimicry between C. jejuni lipopolysaccharides (LPS) and gangliosides. We used

  13. Prevention of Dental Damage and Improvement of Difficult Intubation Using a Paraglossal Technique With a Straight Miller Blade

    Directory of Open Access Journals (Sweden)

    Yu-Feng Huang

    2010-10-01

    Full Text Available Patients with diseased teeth, or those who are difficult to intubate, have a higher risk of dental injury during laryngoscopy. We report 3 cases of smooth endotracheal intubation using a paraglossal technique with a straight Miller blade in patients with poor dentition. Three patients with poor dentition were scheduled to undergo surgery under general anesthesia. All patients presented with extremely loose upper central incisors and had lost the other right upper teeth, while micrognathia and prominent, loose upper incisors were noted in 1 case. We elected to use a straight Miller blade using a paraglossal approach. A nasopharyngeal airway was inserted after induction of general anesthesia to facilitate mask ventilation and prevent air leakage from the mask. The Miller blade was then inserted from the right corner of the mouth, avoiding contact with the vulnerable incisors, and advanced along the groove between the tongue and tonsil. The endotracheal tube was subsequently smoothly inserted after obtaining a grade 1 Cormack and Lehane view without dental trauma in all 3 cases. Direct laryngoscopy using the paraglossal straight blade technique avoids dental damage in patients with mobile upper incisors and no right maxillary molars. It is a practical alternative method that differs from the traditional Macintosh laryngoscope in patients with a high risk of dental injury during the procedure. This technique, which provides an improved view of the larynx, might also be helpful with patients in whom intubation is difficult.

  14. Miller -Fisher syndrome complicated with Guillain -Barr é syndrome:1 case and literature review%Miller-Fisher 综合征合并 Guillain-Barré综合征一例并文献复习

    Institute of Scientific and Technical Information of China (English)

    吕洋; 薛慧; 高思山

    2016-01-01

    目的:探讨Miller-Fisher综合征合并Guillain-Barré综合征的临床特征及治疗方案。方法回顾性分析1例Miller-Fisher综合征合并Guillain-Barré综合征患者的临床资料,并结合文献进行分析。结果该患者发病前有前驱感染史,临床表现为三联征合并肢体无力、球麻痹、双侧面神经麻痹,脑脊液存在蛋白-细胞分离,肌电图提示神经源性损害,予以血浆置换、肾上腺皮质激素等治疗,预后良好。结论 Miller-Fisher综合征合并Guillain-Barré综合征是区别于Miller-Fisher综合征、Guillain-Barré综合征的独立疾病,它有核心的临床特征,应选择正确治疗,以改善预后。%Objective To investigate the clinical characteristics and therapeutic plan of Miller Fisher syn-drome( MFS) complicated with Guillain-Barrésyndrome( GBS) .Methods The clinical data of one patient of MFS complicated with GBS was reviewed retrospectively,and analysis combined with literature review was given.Results The patient had infectious history before the onset of MFS and GBS.Clinical manifestations included MFS triad,bulbar paralysis,bilateral facial paralysis,protein-cell dissociation of cerebrospinal fluid and neurogenic damages in electro-myography.Plasm exchange and adrenocortical hormones treatment were effective.Conclusion MFS complicated with GBS is an independent disease which is different from MFS or GBS.It has its distinct clinical features which should apply appropriate treatment.

  15. MD5加密算法的研究及应用%Research and application of MD5 encryption algorithm

    Institute of Scientific and Technical Information of China (English)

    魏晓玲

    2010-01-01

    针对当前网站建设和系统开发中用户信息等重要数据的安全问题,提出了一种MD5加密算法,可以对用户密码进行加密.MD5加密算法是一种比较常用的单向加密算法,通过对该算法的深入研究,介绍了MD5算法的特性、算法原理及其算法流程,并给出MD5算法在一个具体系统中的实际应用,得出MD5算法是一种非常安全和易用的加密算法.

  16. J-R Curve Determination for Disk-shaped Compact Specimens Based on the Normalization Method and Direct Current Potential Drop Technique

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Xiang [ORNL; Nanstad, Randy K [ORNL; Sokolov, Mikhail A [ORNL

    2014-01-01

    Material ductile fracture toughness can be described by J-integral versus crack extension relationship (J-R curve). As a conventional J-R curve measurement method, unloading compliance (UC) becomes impractical in elevated temperature testing due to relaxation of the material and a friction induced back-up shape of the J-R curve. In addition, the UC method may underpredict the crack extension for standard disk-shaped compact (DC(T)) specimens. In order to address these issues, the normalization method and direct current potential drop (DCPD) technique were applied for determining J-R curves at 24 C and 500 C for 0.18T DC(T) specimens made from type 316L stainless steel. For comparison purchase, the UC method was also applied in 24 C tests. The normalization method was able to yield valid J-R curves in all tests. The J-R curves from the DCPD technique need adjustment to account for the potential drop induced by plastic deformation, crack blunting, etc. and after applying a newly-developed DCPD adjustment procedure, the post-adjusted DCPD J-R curves essentially matched J-R curves from the normalization method. In contrast, the UC method underpredicted the crack extension in all tests resulting in substantial deviation in the derived J-R curves manifested by high Jq values than the normalization or DCPD method. Only for tests where the UC method underpredicted the crack extension by a very small value, J-R curves determined by the UC method were similar to those determined by the normalization or DCPD method.

  17. [Professor Frantisek Por MD and Professor Robert Klopstock MD, students at Budapest and Prague Faculties of Medicine].

    Science.gov (United States)

    Mydlík, M; Derzsiová, K

    2010-11-01

    Professor Frantisek Por MD and Professor Robert Klopstock MD were contemporaries, both born in 1899, one in Zvolen, the other in Dombovar, at the time of Austro-Hungarian Monarchy. Prof. Por attended the Faculty of Medicine in Budapest from 1918 to 1920, and Prof. Klopstock studied at the same place between 1917 and 1919. From 1920 until graduation on 6th February 1926, Prof. Por continued his studies at the German Faculty of Medicine, Charles University in Prague. Prof. Klopstock had to interrupt his studies in Budapest due to pulmonary tuberculosis; he received treatment at Tatranske Matliare where he befriended Franz Kafka. Later, upon Kafka's encouragement, he changed institutions and continued his studies at the German Faculty of Medicine, Charles University in Prague, where he graduated the first great go. It is very likely that, during their studies in Budapest and Prague, both professors met repeatedly, even though their life paths later separated. Following his graduation, Prof. Por practiced as an internist in Prague, later in Slovakia, and from 1945 in Kosice. In 1961, he was awarded the title of university professor of internal medicine at the Faculty of Medicine, Pavol Jozef Safarik University in Kosice, where he practiced until his death in 1980. Prof. Klopstock continued his studies in Kiel and Berlin. After his graduation in 1933, he practiced in Berlin as a surgeon and in 1938 left for USA. In 1962, he was awarded the title of university professor of pulmonary surgery in NewYork, where he died in 1972.

  18. General Charles F. Bolden, Jr. and Professor Claude Nicollier reunite during visit to CERN

    CERN Multimedia

    Jordan Juras

    2011-01-01

    Thursday 23 June, CERN saw an unlikely and much savoured meeting between two old colleagues and friends: General Charles F. Bolden, Jr. and Professor Claude Nicollier.   Bolden and Nicollier were separately invited to CERN for different reasons - Charles Bolden had been invited by Professor Samuel Ting to visit the newly built and now fully operational Payload Operation and Control Centre of the AMS collaboration and Claude Nicollier had been invited by the Theory Department to give a colloquium. They were delightfully surprised when they met at the entrance of the main building. Bolden and Nicollier served together in the Space Shuttle Program and were trained by NASA during the 1980’s where they became close friends. On 24 April, 1990, Bolden piloted the Space Shuttle Discovery into orbit with the Hubble telescope in the payload bay. Though Nicollier did not accompany Bolden during the Hubble launch, he did return to the telescope 3 years later on board the Space Shuttle Ende...

  19. Plutino 15810 (1994 JR1), an accidental quasi-satellite of Pluto

    CERN Document Server

    Marcos, C de la Fuente

    2012-01-01

    In the solar system, quasi-satellites move in a 1:1 mean motion resonance going around their host body like a retrograde satellite but their mutual separation is well beyond the Hill radius and the trajectory is not closed as they orbit the Sun not the host body. So far, minor bodies temporarily trapped in the quasi-satellite dynamical state have been identified around Venus, Earth, the dwarf planet (1) Ceres, the large asteroid (4) Vesta, Jupiter, Saturn and Neptune. Using computer simulations, Tiscareno and Malhotra have predicted the existence of a small but significant population of minor bodies moving in a 1:1 mean motion resonance with Pluto. Here we show using N-body calculations that the Plutino 15810 (1994 JR1) is currently an accidental quasi-satellite of Pluto and it will remain as such for nearly 350,000 yr. By accidental we mean that the quasi-satellite phase is triggered (or terminated) not by a direct gravitational influence in the form of a discrete close encounter but as a result of a resonan...

  20. The Manuel Lujan Jr. Neutron Scattering Center (LANSCE) experiment reports 1993 run cycle. Progress report

    Energy Technology Data Exchange (ETDEWEB)

    Farrer, R.; Longshore, A. [comps.

    1995-06-01

    This year the Manuel Lujan Jr. Neutron Scattering Center (LANSCE) ran an informal user program because the US Department of Energy planned to close LANSCE in FY1994. As a result, an advisory committee recommended that LANSCE scientists and their collaborators complete work in progress. At LANSCE, neutrons are produced by spallation when a pulsed, 800-MeV proton beam impinges on a tungsten target. The proton pulses are provided by the Clinton P. Anderson Meson Physics Facility (LAMPF) accelerator and a associated Proton Storage Ring (PSR), which can Iter the intensity, time structure, and repetition rate of the pulses. The LAMPF protons of Line D are shared between the LANSCE target and the Weapons Neutron Research (WNR) facility, which results in LANSCE spectrometers being available to external users for unclassified research about 80% of each annual LAMPF run cycle. Measurements of interest to the Los Alamos National Laboratory (LANL) may also be performed and may occupy up to an additional 20% of the available beam time. These experiments are reviewed by an internal program advisory committee. This year, a total of 127 proposals were submitted. The proposed experiments involved 229 scientists, 57 of whom visited LANSCE to participate in measurements. In addition, 3 (nuclear physics) participating research teams, comprising 44 scientists, carried out experiments at LANSCE. Instrument beam time was again oversubscribed, with 552 total days requested an 473 available for allocation.

  1. Organic Analysis in the Miller Range 090657 CR2 Chondrite: Part 2 Amino Acid Analyses

    Science.gov (United States)

    Burton, A. S.; Cao, T.; Nakamura-Messenger, K.; Berger, E. L.; Messenger, S.; Clemett, S. J.; Aponte, J. C.; Elsila, J. E.

    2016-01-01

    Primitive carbonaceous chondrites contain a wide variety of organic material, ranging from soluble discrete molecules to insoluble, unstructured kerogen-like components, as well as structured nano-globules of macromolecular carbon. The relationship between the soluble organic molecules, macromolecular organic material, and host minerals are poorly understood. Due to the differences in extractability of soluble and insoluble organic materials, the analysis methods for each differ and are often performed independently. The combination of soluble and insoluble analyses, when performed concurrently, can provide a wider understanding of spatial distribution, and elemental, structural and isotopic composition of organic material in primitive meteorites. Using macroscale extraction and analysis techniques in combination with in situ microscale observation, we have been studying both insoluble and soluble organic material in the primitive CR2 chondrite Miller Range (MIL) 090657. In accompanying abstracts (Cao et al. and Messenger et al.) we discuss insoluble organic material in the samples. By performing the consortium studies, we aim to improve our understanding of the relationship between the meteorite minerals and the soluble and insoluble organic phases and to delineate which species formed within the meteorite and those that formed in nebular or presolar environments. In this abstract, we present the results of amino acid analyses of MIL 090657 by ultra performance liquid chromatography with fluorescence detection and quadrupole-time of flight mass spectrometry. Amino acids are of interest because they are essential to life on Earth, and because they are present in sufficient structural, enantiomeric and isotopic diversity to allow insights into early solar system chemical processes. Furthermore, these are among the most isotopically anomalous species, yet at least some fraction are thought to have formed by aqueously-mediated processes during parent body alteration.

  2. Structural Modifications of Fructans in Aloe barbadensis Miller (Aloe Vera Grown under Water Stress.

    Directory of Open Access Journals (Sweden)

    Carlos Salinas

    Full Text Available Aloe barbadensis Miller (Aloe vera has a Crassulaceae acid metabolism which grants the plant great tolerance to water restrictions. Carbohydrates such as acemannans and fructans are among the molecules responsible for tolerating water deficit in other plant species. Nevertheless, fructans, which are prebiotic compounds, have not been described nor studied in Aloe vera, whose leaf gel is known to possess beneficial pharmaceutical, nutritional and cosmetic properties. As Aloe vera is frequently cultivated in semi-arid conditions, like those found in northern Chile, we investigated the effect of water deficit on fructan composition and structure. For this, plants were subjected to different irrigation regimes of 100%, 75%, 50% and 25% field capacity (FC. There was a significant increase in the total sugars, soluble sugars and oligo and polyfructans in plants subjected to water deficit, compared to the control condition (100% FC in both leaf tips and bases. The amounts of fructans were also greater in the bases compared to the leaf tips in all water treatments. Fructans also increase in degree of polymerization with increasing water deficit. Glycosidic linkage analyses by GC-MS, led to the conclusion that there are structural differences between the fructans present in the leaves of control plants with respect to plants irrigated with 50% and 25% FC. Therefore, in non-stressed plants, the inulin, neo-inulin and neo-levan type of fructans predominate, while in the most stressful conditions for the plant, Aloe vera also synthesizes fructans with a more branched structure, the neofructans. To our knowledge, the synthesis and the protective role of neo-fructans under extreme water deficit has not been previously reported.

  3. Calculation of autoionization positions and widths with applications to Penning ionization reactions. [Miller golden rule formula

    Energy Technology Data Exchange (ETDEWEB)

    Isaacson, A.D.

    1978-08-01

    Using an approximate evaluation of Miller's golden rule formula to calculate autoionization widths which allows for the consideration only of L/sup 2/ functions, the positions and lifetimes of the lowest /sup 1/,/sup 3/P autoionizing states of He have been obtained to reasonable accuracy. This method has been extended to molecular problems, and the ab initio configuration interaction potential energy and width surfaces for the He(2/sup 3/S) + H/sub 2/ system have been obtained. Quantum mechanical close-coupling calculations of ionization cross sections using the complex V* - (i/2) GAMMA-potential have yielded rate constants in good agreement with the experimental results of Lindinger, et al. The potential energy surface of the He(2/sup 1/S) + H/sub 2/ system has also been obtained and exhibits not only a high degree of anisotropy, but also contains a relative maximum for a perpendicular (C/sub 2//sub v/) approach which appears to arise from s-p hybridization of the outer He orbital. However, similar ab initio calculations on the He(2/sup 1/S) + Ar system do not show such anomalous structure. In addition, the complex poles of the S-matrix (Siegert eigenvalues) were calculated for several autoionizing states of He and H/sup -/, with encouraging results even for quite modest basis sets. This method was extended to molecular problems, and results obtained for the He(2/sup 3/S) + H and He(2/sup 1/S) + H systems. 75 references.

  4. Structural Modifications of Fructans in Aloe barbadensis Miller (Aloe Vera) Grown under Water Stress

    Science.gov (United States)

    Salinas, Carlos; Cardemil, Liliana

    2016-01-01

    Aloe barbadensis Miller (Aloe vera) has a Crassulaceae acid metabolism which grants the plant great tolerance to water restrictions. Carbohydrates such as acemannans and fructans are among the molecules responsible for tolerating water deficit in other plant species. Nevertheless, fructans, which are prebiotic compounds, have not been described nor studied in Aloe vera, whose leaf gel is known to possess beneficial pharmaceutical, nutritional and cosmetic properties. As Aloe vera is frequently cultivated in semi-arid conditions, like those found in northern Chile, we investigated the effect of water deficit on fructan composition and structure. For this, plants were subjected to different irrigation regimes of 100%, 75%, 50% and 25% field capacity (FC). There was a significant increase in the total sugars, soluble sugars and oligo and polyfructans in plants subjected to water deficit, compared to the control condition (100% FC) in both leaf tips and bases. The amounts of fructans were also greater in the bases compared to the leaf tips in all water treatments. Fructans also increase in degree of polymerization with increasing water deficit. Glycosidic linkage analyses by GC-MS, led to the conclusion that there are structural differences between the fructans present in the leaves of control plants with respect to plants irrigated with 50% and 25% FC. Therefore, in non-stressed plants, the inulin, neo-inulin and neo-levan type of fructans predominate, while in the most stressful conditions for the plant, Aloe vera also synthesizes fructans with a more branched structure, the neofructans. To our knowledge, the synthesis and the protective role of neo-fructans under extreme water deficit has not been previously reported. PMID:27454873

  5. Structural Modifications of Fructans in Aloe barbadensis Miller (Aloe Vera) Grown under Water Stress.

    Science.gov (United States)

    Salinas, Carlos; Handford, Michael; Pauly, Markus; Dupree, Paul; Cardemil, Liliana

    2016-01-01

    Aloe barbadensis Miller (Aloe vera) has a Crassulaceae acid metabolism which grants the plant great tolerance to water restrictions. Carbohydrates such as acemannans and fructans are among the molecules responsible for tolerating water deficit in other plant species. Nevertheless, fructans, which are prebiotic compounds, have not been described nor studied in Aloe vera, whose leaf gel is known to possess beneficial pharmaceutical, nutritional and cosmetic properties. As Aloe vera is frequently cultivated in semi-arid conditions, like those found in northern Chile, we investigated the effect of water deficit on fructan composition and structure. For this, plants were subjected to different irrigation regimes of 100%, 75%, 50% and 25% field capacity (FC). There was a significant increase in the total sugars, soluble sugars and oligo and polyfructans in plants subjected to water deficit, compared to the control condition (100% FC) in both leaf tips and bases. The amounts of fructans were also greater in the bases compared to the leaf tips in all water treatments. Fructans also increase in degree of polymerization with increasing water deficit. Glycosidic linkage analyses by GC-MS, led to the conclusion that there are structural differences between the fructans present in the leaves of control plants with respect to plants irrigated with 50% and 25% FC. Therefore, in non-stressed plants, the inulin, neo-inulin and neo-levan type of fructans predominate, while in the most stressful conditions for the plant, Aloe vera also synthesizes fructans with a more branched structure, the neofructans. To our knowledge, the synthesis and the protective role of neo-fructans under extreme water deficit has not been previously reported.

  6. On the adiabatic representation of Meyer-Miller electronic-nuclear dynamics.

    Science.gov (United States)

    Cotton, Stephen J; Liang, Ruibin; Miller, William H

    2017-08-14

    The Meyer-Miller (MM) classical vibronic (electronic + nuclear) Hamiltonian for electronically non-adiabatic dynamics-as used, for example, with the recently developed symmetrical quasiclassical (SQC) windowing model-can be written in either a diabatic or an adiabatic representation of the electronic degrees of freedom, the two being a canonical transformation of each other, thus giving the same dynamics. Although most recent applications of this SQC/MM approach have been carried out in the diabatic representation-because most of the benchmark model problems that have exact quantum results available for comparison are typically defined in a diabatic representation-it will typically be much more convenient to work in the adiabatic representation, e.g., when using Born-Oppenheimer potential energy surfaces (PESs) and derivative couplings that come from electronic structure calculations. The canonical equations of motion (EOMs) (i.e., Hamilton's equations) that come from the adiabatic MM Hamiltonian, however, in addition to the common first-derivative couplings, also involve second-derivative non-adiabatic coupling terms (as does the quantum Schrödinger equation), and the latter are considerably more difficult to calculate. This paper thus revisits the adiabatic version of the MM Hamiltonian and describes a modification of the classical adiabatic EOMs that are entirely equivalent to Hamilton's equations but that do not involve the second-derivative couplings. The second-derivative coupling terms have not been neglected; they simply do not appear in these modified adiabatic EOMs. This means that SQC/MM calculations can be carried out in the adiabatic representation, without approximation, needing only the PESs and the first-derivative coupling elements. The results of example SQC/MM calculations are presented, which illustrate this point, and also the fact that simply neglecting the second-derivative couplings in Hamilton's equations (and presumably also in the Schr

  7. A Case Presentation of a Third-Nerve Palsy as a Characteristic of Miller Fisher Syndrome

    Directory of Open Access Journals (Sweden)

    Trennda L. Rittenbach, OD

    2014-07-01

    Full Text Available Background: A rare clinical variant of Guillain-Barre syndrome, known as Miller Fisher syndrome (MFS, is an immunemediated neuropathy classically characterized by a triad consisting of ophthalmoplegia, ataxia, and areflexia.1,2 Although MFS is thought to be a disease of immunological basis, other pathological entities may give rise to the syndrome as well. The diagnosis of MFS relies upon clinical signs, a combination of lab tests including antibody serum, cerebrospinal fluid, and electrophysiological findings. Understanding the clinical course of MFS and its ocular components can aid in the rehabilitation and co-management of these patients. Case Report: A 79-year-old white male presented with a four day onset of double vision and an inability to walk unassisted. An examination revealed a pupil-sparing third-nerve palsy with a left eye ptosis. Due to the patient being in moderate pain throughout his entire body and presenting with an acute onset of symptoms, the patient was sent to the emergency room in the same hospital building. The patient was immediately admitted for evaluation and testing which revealed the diagnosis of MFS. Conclusions: Although a complaint of diplopia can lead to an array of diagnoses, when accompanied by an acute inability to walk, MFS should be on the list of possible causes. Although mostly a self-limiting disease, there is the possibility of progressing to respiratory failure. Knowledge of the syndrome, its clinical course, and prognosis, along with an appropriate evaluation with current laboratory testing, will lead to the proper diagnosis, treatment, and management.

  8. Medicinal Cannabis in California: An Interview with Igor Grant, MD.

    Science.gov (United States)

    Piomelli, Daniele; Grant, Igor

    2016-01-01

    Dr. Igor Grant, MD, is distinguished professor and chair of psychiatry and director of the HIV Neurobehavioral Research Program and the Center for Medicinal Cannabis Research at the University of California, San Diego. Dr. Grant is a neuropsychiatrist who graduated from the University of British Columbia School of Medicine (1966), and received specialty training in psychiatry at the University of Pennsylvania (1967-1971), and additional training in neurology at the Institute of Neurology (1980-1981), London, U.K. Dr. Grant's academic interests focus on the effects of various diseases on brain and behavior, with an emphasis on translational studies in HIV, and drugs of abuse. He has contributed to ∼700 scholarly publications and is principal investigator of several NIH studies, including an NIDA P50 (Translational Methamphetamine AIDS Research Center-TMARC), and is codirector of the HIV Neurobehavioral Research Center (HNRC).

  9. A workshop on leadership for MD/PhD students

    Directory of Open Access Journals (Sweden)

    Mark D. Cannon

    2011-08-01

    Full Text Available Success in academic medicine requires scientific and clinical aptitude and the ability to lead a team effectively. Although combined MD/PhD training programs invest considerably in the former, they often do not provide structured educational opportunities in leadership, especially as applied to investigative medicine. To fill a critical knowledge gap in physician-scientist training, the Vanderbilt Medical Scientist Training Program (MSTP developed a biennial two-day workshop in investigative leadership. MSTP students worked in partnership with content experts to develop a case-based curriculum and deliver the material. In its initial three offerings in 2006, 2008, and 2010, the workshop was judged by MSTP student attendees to be highly effective. The Vanderbilt MSTP Leadership Workshop offers a blueprint for collaborative student-faculty interactions in curriculum design and a new educational modality for physician-scientist training.

  10. The Achromatic Telescopic Squeezing (ATS) MD part II

    CERN Document Server

    Fartoukh, S; De Maria, R; Miyamoto, R; Mueller, G; Ponce, L; Redaelli, S; Strzelczyk, M; Tomas, R; Vanbavinckhove, G; Wenninger, J; Albert, M; Giachino, R; Giovannozzi, M; Goddard, B; Hagen, P; Hofle, W; Kain, V; Macpherson, A; Normann, L; Papotti, G; Steinhagen, R; Valuch, D; wollman, D

    2011-01-01

    This note describes the results obtained during the second so-called ATS MD where the record of Beta* was reached at IP1 and IP5 with a “pre-squeezed” Beta* of 1.2 m, while perfectly controlling the chromatic aberrations induced (non-linear chromaticity, off-momentum Beta-beating). Then, the ATLAS insertion was squeezed further down to the target of the former LHC Upgrade Project (Phase I), that is to Beta* = 30 cm, using the Achromatic Telescopic Squeezing techniques. In view of this major achievement, the bar is fixed even higher for the next ATS MD’s, with an ultimate Beta* targeted to 10 cm for the two high-luminosity insertions ATLAS and CMS.

  11. Luminosity Anti-leveling with Crossing Angle (MD 1669)

    CERN Document Server

    Gorzawski, Arkadiusz; Ponce, Laurette; Salvachua Ferrando, Belen Maria; Wenninger, Jorg; CERN. Geneva. ATS Department

    2016-01-01

    A significant fraction of the LHC luminosity ($\\sim$30\\% in 2016) is lost due to the presence (and necessity) of the crossing angles at the IPs. At the LHC the crossing angle is typically set to a value that provides sufficient separation of the beams at the start of fills for the peak bunch intensities. As the bunch intensity decays during a fill, it is possible to reduce the crossing angle and recover some luminosity. A smooth crossing angle reduction procedure must be developed to take advantage of this option during stable beam operation. During this MD a smooth procedure for luminosity leveling with crossing angle was tested. It was demonstrated that the orbit was well controlled, beam losses were low and the offset leveled experiments ALICE and LHCb were not affected by crossing angle leveling in ATLAS and CMS.

  12. Emily Dickinson's ophthalmic consultation with Henry Willard Williams, MD.

    Science.gov (United States)

    Blanchard, Donald L

    2012-12-01

    Emily Dickinson is one of America's premier poets of the 19th century. Henry Willard Williams, MD, was one of the very first physicians to limit his practice to ophthalmology and was the established leader in his field in Boston, Massachusetts. They met during the time of the Civil War, when Emily consulted him about her ophthalmic disorder. No records of the diagnosis survive. Photophobia, aching eyes, and a restriction in her ability to work up close were her main symptoms. Iritis, exotropia, or psychiatric problems are the most frequent diagnoses offered to explain her difficulties. Rather than attempt a definitive conclusion, this article will offer an additional possibility that Dr Williams likely considered (ie, hysterical hyperaesthesia of the retina). This was a common diagnosis at that time, although it has currently faded from use.

  13. Morris Fishbein, M.D.: the "medical Mussolini" and chiropractic.

    Science.gov (United States)

    Donahue, J H

    1996-06-01

    Morris Fishbein, M.D. is the most important non-chiropractor to influence the chiropractic profession. From his post as editor and secretary of the American Medical Association, his anti-chiropractic writings, speeches and political activities had a profound effect on the profession's development. Because he was not only the foremost medical politician of the time, but also perceived as a multi-faceted author on public health issues, his credibility was high across large sections of the population and in most social institutions. His tactics and stature undoubtedly helped keep the profession limited to caring for a small percentage of the population. Because of him, chiropractors devised survival strategies that continue to influence the profession even today.

  14. The improvement of cryptography MD5 algorithm%密码学中信息摘要算法MD5的改进

    Institute of Scientific and Technical Information of China (English)

    林平

    2011-01-01

    MD5算法的基础上,针对MD5算法密文是一个32位16进制字符来表示值的特征,提出MD5改进算法,首先采用替换加密算法Md5Replace加密MD5算法密文,隐藏MD5算法密文的特征;再选定替换加密密文中某一位置插入由随机函数算法Md5Random产生定长的字符串得到最后的密文,改变了替换加密密文位数,隐藏了替换加密算法替换规律.在不改变算法效率的前提下,提高算法安全强度.

  15. MD5碰撞攻击的差分路径构建%Constructing Differential Path in MD5 Collision Attack

    Institute of Scientific and Technical Information of China (English)

    刘凡保; 谢涛

    2009-01-01

    著名的杂凑算法MD5是MD4的增强版本,由Ronald L.Rivest在1991年设计.MD5广泛应用于口令变换、数据完整性、数字证书等领域.近年最具影响的MD5安全性的分析结果是王小云首次发现的MD5碰撞.之后,MD5碰撞攻击的改进主要集中在提高碰撞对搜索的性能.基于新的不同于王小云的明文差分构成的MD5碰撞,介绍差分路径的构建方法,并给出一条差分路径以及碰撞对数据.

  16. Leonard F. Peltier, MD, PhD, 1920-2003.

    Science.gov (United States)

    Reckling, Frederick W; Lo Vecchio, Janolyn G; Reckling, JoAnn B

    2004-05-01

    Leonard F. Peltier, MD, PhD, was an orthopaedic surgeon, academician, administrator, laboratory investigator, historian, and mentor. His career spanned nearly six decades, beginning with graduate education at the University of Minnesota (UM) under the auspices of Owen H. Wangensteen, MD, PhD. In addition to obtaining a PhD in physiology in the UM Graduate School, he completed general and orthopaedic surgery residencies and attained board certification in each specialty. He served in the US Army Occupation Force Medical Corps in Germany just after World War II. In 1957, at 37 years old, he assumed the chairmanship of the orthopaedic training program at the University of Kansas. In 1971, he couldn't resist the opportunity to become one of the founding members of the "start-up" University of Arizona College of Medicine, accepting an appointment as chair of the new orthopaedic training program, where he remained until his retirement in 1990. He took clinical problems to the laboratory, and made important scientific contributions, particularly in the area of fat embolism and in using calcium sulfate (plaster of Paris) to fill bone defects. He served on governing boards of national professional organizations and presided over the American Association for the Surgery of Trauma from 1980-1981. Throughout his career, he was fascinated by, and published extensively in, the history of medicine arena. Known fondly as "the professor" to many of his residents and colleagues, he had a pragmatic, honest, upbeat, and often humorous approach to life's challenges, valuing personal integrity above other virtues. He explored various eclectic interests far beyond his professional contributions while maintaining his family as a central priority. With his exemplary productivity and interests in the surgical and laboratory sciences, history of medicine, appreciation of fine arts, and perceptive and effective interactions with family, friends, patients, and colleagues, the memory of Leonard

  17. 报文摘要算法MD5的分析与改进

    Institute of Scientific and Technical Information of China (English)

    汪勋亮; 赵春霞; 郭剑辉

    2014-01-01

    MD5算法在数据加密方面有着广泛的应用,但是它无法抵御查字典攻击和差分等攻击。为此本文介绍了报文算法MD5和Base64算法,以及在两种算法的基础上提出了MD5的改进算法,以应对以上被攻击的缺陷。%MD5 encryption algorithm in the data has a wide range of applications,but it can not resist dictionary attacks and differential attacks.This paper introduces the MD5 message digest algorithm and Base64 algorithm,and two algorithms based on the proposed the improved MD5 algorithm,the effect is to deal with the above attack.

  18. The MD5 Technical Analysis and Improvement Measures%MD5技术解析及改进措施

    Institute of Scientific and Technical Information of China (English)

    窦立莉

    2010-01-01

    随着网络的迅速普及,信息加密技术的发展对保障网络安全有着重大的作用与意义.本文对MD5 这种单向加密算法进行了简要描述,对MD5 算法的原理进行了深入分析,并提出了MD5 码的多种改进措施.

  19. Alternatively spliced myeloid differentiation protein-2 (MD-2s) protein inhibits TLR4-mediated lung inflammation

    Science.gov (United States)

    Tumurkhuu, Gantsetseg; Dagvadorj, Jargalsaikhan; Jones, Heather D.; Chen, Shuang; Shimada, Kenichi; Crother, Timothy R.; Arditi, Moshe

    2014-01-01

    We previously identified a novel alternatively spliced isoform of human myeloid differentiation protein-2 (MD-2s) that competitively inhibits binding of MD-2 to TLR4 in vitro. Here we investigated the protective role of MD-2s in LPS-induced acute lung injury by delivering intracheally (i.t.) an adenovirus construct that expressed MD-2s (Ad-MD-2s). After adenovirus-mediated gene transfer, MD-2s was strongly expressed in lung epithelial cells and readily detected in bronchoalveolar lavage fluid (BALF). Compared to Ad-EV control mice, Ad-MD-2s delivery resulted in significantly less LPS-induced inflammation in the lungs, including less protein leakage, cell recruitment, and expression of proinflammatory cytokines and chemokines, such as IL-6, KC, and MIP-2. BALF from Ad-MD-2s mice transferred into lungs of naive mice before i.t. LPS challenge diminished pro-inflammatory cytokine levels. As house dust mite (HDM) sensitization is dependent on TLR4 and HDM Der p 2, a structural homolog of MD-2, we also investigated the effect of MD-2s on house dust mite (HDM)-induced allergic airway inflammation. Ad-MD-2s given before HDM sensitization significantly inhibited subsequent allergic airway inflammation after HDM challenge, including reductions in eosinophils, goblet cell hyperplasia, and IL-5 levels. Our study indicates that the alternatively spliced short isoform of human MD-2 could be a potential therapeutic candidate to treat human diseases induced or exacerbated by TLR4 signaling, such as Gram-negative bacterial endotoxin-induced lung injury and house dust mite-triggered allergic lung inflammation. PMID:25576596

  20. MD-2 Determinants of Nickel and Cobalt-Mediated Activation of Human TLR4

    Science.gov (United States)

    Oblak, Alja; Pohar, Jelka; Jerala, Roman

    2015-01-01

    Recent findings unexpectedly revealed that human TLR4 can be directly activated by nickel ions. This activation is due to the coordination of nickel by a cluster of histidine residues on the ectodomain of human TLR4, which is absent in most other species. We aimed to elucidate the role of MD-2 in the molecular mechanism of TLR4/MD-2 activation by nickel, as nickel binding site on TLR4 is remote from MD-2, which directly binds the endotoxin as the main pathological activator of TLR4. We identified MD-2 and TLR4 mutants which abolished TLR4/MD-2 receptor activation by endotoxin but could nevertheless be significantly activated by nickel, which acts in synergy with LPS. Human TLR4/MD-2 was also activated by cobalt ions, while copper and cadmium were toxic in the tested concentration range. Activation of TLR4 by cobalt required MD-2 and was abolished by human TLR4 mutations of histidine residues at positions 456 and 458. We demonstrated that activation of TLR4 by nickel and cobalt ions can trigger both the MyD88-dependent and the –independent pathway. Based on our results we propose that predominantly hydrophobic interactions between MD-2 and TLR4 contribute to the stabilization of the TLR4/MD-2/metal ion complex in a conformation that enables activation. PMID:25803856

  1. Crystallization and preliminary X-ray crystallographic analysis of polyphenol oxidase from Juglans regia (jrPPO1).

    Science.gov (United States)

    Zekiri, Florime; Bijelic, Aleksandar; Molitor, Christian; Rompel, Annette

    2014-06-01

    Tyrosinase is a type 3 copper enzyme that catalyzes the ortho-hydroxylation of monophenols to diphenols as well as their subsequent oxidation to quinones, which are precursors for the biosynthesis of melanins. The first plant tyrosinase from walnut leaves (Juglans regia) was purified to homogeneity and crystallized. During the purification, two forms of the enzyme differing only in their C-termini [jrPPO1(Asp101-Pro444) and jrPPO1(Asp101-Arg445)] were obtained. The most abundant form jrPPO1(Asp101-Arg445), as described in Zekiri et al. [Phytochemistry (2014), 101, 5-15], was crystallized, resulting in crystals that belonged to space group C121, with unit-cell parameters a=115.56, b=91.90, c=86.87 Å, α=90, β=130.186, γ=90°, and diffracted to 2.39 Å resolution. Crystals were only obtained from solutions containing at least 30% polyethylene glycol 5000 monomethyl ether in a close-to-neutral pH range.

  2. Red, Rough, Fast, and Perturbed: New Horizons Observations of KBO (15810) 1994 JR1 from the Kuiper Belt

    CERN Document Server

    Porter, Simon B; Benecchi, Susan; Verbiscer, Anne; Zangari, Amanda M; Weaver, H A; Lauer, Tod R; Parker, Alex H; Buie, Marc W; Cheng, Andrew F; Young, Leslie A; Olkin, Cathy B; Ennico, Kimberly; Stern, S Alan

    2016-01-01

    The 3:2 resonant KBO (15810) 1994 JR1 was observed by NASA's New Horizons spacecraft on November 2, 2015 from a distance of 1.85 AU, and again on April 7, 2016 from a distance of 0.71 AU. Acquired using the LOng Range Reconnaissance Imager (LORRI), these were the first close observations of any KBO other than Pluto, and the first ever of a small KBO. Combining ground-based and HST observations at small phase angles and the LORRI observations at higher phase angles, we produced the first disk-integrated solar phase curve of a typical KBO from alpha=0.6-58 degrees. Observations at these geometries, attainable only from a spacecraft in the outer Solar System, constrain surface properties such as macroscopic roughness and the single particle phase function. 1994 JR1 has a rough surface with a 37+/-5 degree mean topographic slope angle and has a relatively rapid rotation period of 5.47+/-0.33 hours. 1994 JR1 is currently 2.7 AU from Pluto; our astrometric points enable high-precision orbit determination and integr...

  3. Emil Godlewski, Jr. (1875-1944) pioneer of embryology at the Jagiellonian University of Krakow (Poland).

    Science.gov (United States)

    Sliwa, Leopold

    2008-01-01

    Emil Godlewski, Jr. (1875-1944) lived and worked in Krakow. He graduated from the Faculty of Medicine of the Jagiellonian University with the title of Doctor of Medical Science. He worked at the Faculty of Medicine, first in the Institute of Descriptive Anatomy and later as Professor of Biology and Embryology in the Department of Biology and Embryology, which he founded and led for many years. After early research on the development and histogenesis of muscles, professor Godlewski's scientific interests focused on regeneration and mechanisms regulating the process of fertilization, as well as early embryo development, blastulation and gastrulation. He was also interested in the origin of the primary differentiating cells in regenerates. He postulated the importance of epithelial tissue in this process and was the first to point out the change in the function, organization and role of the cells under the influence of external stimuli. Investigating fertilization and early development, he focused on the cooperation between the nucleus and the cytoplasm in the regulation of the early stages of development. Godlewski was also the author of the theory of migration of the inherited substances from the nucleus to the cytoplasm and, after their processing, from the cytoplasm to the nucleus. His works were never fragmentary, but always synthetical attempts at explaining important issues relating to the mechanisms of development. In 1936 Professor Godlewski was awarded the title of Member of the Pontifica Accademia delle Scienze. Apart from doing research and teaching, Emil Godlewski devoted a lot of time to social issues, especially those connected to medicine. When Poland regained independence after World War I, he actively participated in the reopening of the Jagiellonian University.

  4. Iterative redundant encryption based on MD5 algorithm%基于MD5的迭代冗余加密算法

    Institute of Scientific and Technical Information of China (English)

    王津涛; 覃尚毅; 王冬梅

    2007-01-01

    MD5报文摘要算法是一种非常流行的加密方案,是对任意长度的消息提取数字指纹或消息摘要的算法,但是,在计算上难以提供两个具有相同数字指纹的不同消息,并难以由给定的数字指纹推算出相应的消息.基于MD5的迭代冗余加密算法对MD5算法进行了扩展,利用了MD5算法的强大安全性,实现了文件加密、解密和数据完整性保护的功能.

  5. MD5算法的过程分析及其C#实现%Process Analysis of MD5 Algorithm and Its C# realization

    Institute of Scientific and Technical Information of China (English)

    杜昌钰

    2008-01-01

    文章对MD5即"Message-Digest Algorithm 5(报文流行的C#对8D5算法进行了具体的实现,给出了一个具体的C#加密实例.虽然MD5因王小云教授在2004国际密码学会议(Crypto'2004)上发表的论文受到了前所未有的冲击,但MD5在一些非关键领域应用还是相当广泛.最后还提出了一些针对MD5现状的解决对策和建议.

  6. Antibacterial and antioxidant activities in Sideritis italica (Miller) Greuter et Burdet essential oils.

    Science.gov (United States)

    Basile, Adriana; Senatore, Felice; Gargano, Rosalba; Sorbo, Sergio; Del Pezzo, Marisa; Lavitola, Alfredo; Ritieni, Alberto; Bruno, Maurizio; Spatuzzi, Daniela; Rigano, Daniela; Vuotto, Maria Luisa

    2006-09-19

    Sideritis italica (Miller) Greuter et Burdet is a widespread Lamiacea in the Mediterranean region used in traditional medicine. Essential oils were antibacterial against nine ATCC and as many clinically isolated Gram-positive and Gram-negative bacterial strains. Antibacterial activity was also found against Helicobacter pylori: a dose-dependant inhibition was shown between 5 and 25 microg/ml. The antibacterial activity of the oils was expressed as MICs (minimum inhibitory concentrations) and MBCs (minimum bactericidal concentrations). At a concentration between 3.9 and 250 microg/ml the oils showed a significant antibacterial effect against both Gram-negative and Gram-positive bacteria. In particular the ATCC strains Pseudomonas aeruginosa (MIC=3.9 microg/ml and 7.8 for flowerheads and leaves, respectively), Proteus mirabilis (MIC=15.6 and 7.8 microg/ml), Salmonella typhi (MIC=7.8 microg/ml) and Proteus vulgaris (MIC=15.6 microg/ml) were the most inhibited. Only Pseudomonas aeruginosa showed MBC at a concentration between 62.6 and 125 microg/ml. The antioxidant activity of the essential oils was evaluated by two cell free colorimetric methods: ABTS and DMPD; leaf oil is more active (4.29 +/- 0.02 trolox equivalents and 4.53 +/- 0.67 ascorbic acid equivalents by ABTS and DMPD, respectively). Finally the antioxidant activity of the essential oils was also evaluated by their effects on human whole blood leukocytes (WB) and on isolated polymorphonucleate (PMN) chemiluminescence. Comparing the effects of the oils from leaves and flowerheads on both PMN and WB chemiluminescence emission, we found no significant differences. Essential oils showed a dose-dependent and linear inhibitory activity on isolated PMN as well as on WB CL emission when PMA-stimulated. On the contrary, the inhibitory activity on resting cells was nonlinear. Our data represent an answer to the continual demand for new antibiotics and antioxidants for the continuous emergence of antibiotic

  7. Simulation of organic molecule formation in solar system environments-The Miller-Urey Experiment in Space project overview

    Science.gov (United States)

    Kotler, J. Michelle; Ehrenfruend, Pascale; Botta, Oliver; Blum, Jurgen; Schrapler, Rainer; van Dongen, Joost; Palmans, Anja; Sephton, Mark A.; Martins, Zita; Cleaves, Henderson J.; Ricco, Antonio

    The Miller-Urey Experiment in space (MUE) investigates the formation of potential prebiotic organic compounds in the early solar system environment. The MUE experiment will be sent to and retrieved from the International Space Station (ISS), where it will be performed inside the Microgravity Science Glovebox (MSG). The goal of this space experiment is to understand prebiotic reactions in microgravity by simulating environments of the early solar nebula. The dynamic environment of the solar nebula with the simultaneous presence of gas, particles, and energetic processes, including shock waves, lightning, and radiation may trigger a rich organic chemistry leading to organic molecules. These environments will be simulated in six fabricated vials containing various gas mixtures as well as solid particles. Two gas mixture compositions will be tested and subjected to continuous spark discharges for 48, 96, and 192 hours. Silicate particles will serve as surfaces on which thin water ice mantles can accrete. The particles will move repeatedly through a high-voltage spark discharge in microgravity, enabling chemical re-actions analogous to the original Miller-Urey experiment. The experiment will be performed at low temperatures (-5 C), slowing hydrolysis and improving chances of detection of interme-diates, initial products, and their distributions. Executing the Miller-Urey experiment in the space environment (microgravity) allows us to simulate conditions that could have prevailed in the energetic early solar nebula and provides insights into the chemical pathways that may occur in forming planetary systems. Analysis will be performed post-flight using chemical analytical methods. The anticipated results will provide information about chemical reaction pathways to form organic compounds in space environment, emphasizing abiotic chemical pathways and mechanisms that could have been crucial in the formation of biologically relevant compounds such as amino acids and

  8. ASP网站用户帐号的MD5加密技术%The Encryption Techniques of MD5 about User Accounts in ASP Web

    Institute of Scientific and Technical Information of China (English)

    田文艳

    2007-01-01

    本文介绍了Asp中的MD5(Message-Digest Algorithm 5)加密技术,分析了它的工作原理及使用过程,并通过具体的使用实例,说明了MD5加密技术在网站开发中的具体实现方法.

  9. Comparison of Basic Science Knowledge Between DO and MD Students.

    Science.gov (United States)

    Davis, Glenn E; Gayer, Gregory G

    2017-02-01

    With the coming single accreditation system for graduate medical education, medical educators may wonder whether knowledge in basic sciences is equivalent for osteopathic and allopathic medical students. To examine whether medical students' basic science knowledge is the same among osteopathic and allopathic medical students. A dataset of the Touro University College of Osteopathic Medicine-CA student records from the classes of 2013, 2014, and 2015 and the national cohort of National Board of Medical Examiners Comprehensive Basic Science Examination (NBME-CBSE) parameters for MD students were used. Models of the Comprehensive Osteopathic Medical Licensing Examination-USA (COMLEX-USA) Level 1 scores were fit using linear and logistic regression. The models included variables used in both osteopathic and allopathic medical professions to predict COMLEX-USA outcomes, such as Medical College Admission Test biology scores, preclinical grade point average, number of undergraduate science units, and scores on the NBME-CBSE. Regression statistics were studied to compare the effectiveness of models that included or excluded NBME-CBSE scores at predicting COMLEX-USA Level 1 scores. Variance inflation factor was used to investigate multicollinearity. Receiver operating characteristic curves were used to show the effectiveness of NBME-CBSE scores at predicting COMLEX-USA Level 1 pass/fail outcomes. A t test at 99% level was used to compare mean NBME-CBSE scores with the national cohort. A total of 390 student records were analyzed. Scores on the NBME-CBSE were found to be an effective predictor of COMLEX-USA Level 1 scores (Pdifference was found in performance on the NBME-CBSE between osteopathic and allopathic medical students (P=.322). As an examination constructed to assess the basic science knowledge of allopathic medical students, the NBME-CBSE is effective at predicting performance on COMLEX-USA Level 1. In addition, osteopathic medical students performed the same as

  10. Miller-Urey and Beyond: What Have We Learned About Prebiotic Organic Synthesis Reactions in the Past 60 Years?

    Science.gov (United States)

    McCollom, Thomas M.

    2013-05-01

    The synthesis of amino acids in the Miller-Urey spark-discharge experiments in the early 1950s inspired a strong interest in experimental studies of prebiotic organic chemistry that continues today. Over the years, many of the basic building blocks of life as we know it have been synthesized in the laboratory from simple ingredients, including amino acids, sugars, nucleobases, and membrane-forming lipids. Questions remain, however, concerning whether the conditions that allow synthesis of these compounds in the laboratory accurately simulate those that might have been present on the early Earth, and a closer convergence between plausible prebiotic conditions and laboratory simulations remains a challenge for experimentalists.

  11. Henry Miller : pintura e escrita : algumas notas breves em torno de "To paint is to love again"

    OpenAIRE

    2014-01-01

    Taking some of the main aspects of H. Miller's confessional essay To paint is to love again as a departure point, in the present text the author tries to expose the relationship that can be established between painting and writing, and even philosophy, in the work of the American novelist, not only from the perspective of a mere categorial classification, or as a simple exercise for the understanding of the meaning of his books and paintings on the basis of thematic analogies, but as a proces...

  12. Los costos de la desinflación en Colombia según el modelo Buiter-Miller

    Directory of Open Access Journals (Sweden)

    Ramírez Vigoya Alejandro

    2005-12-01

    Full Text Available En este artículo analizamos los costos del proceso desinflacionario colombiano entre 1998 y 2003, utilizamos un modelo VAR estructural con restricciones de corto y largo plazo basado en el modelo Buiter-Miller (1982, el cual analiza los efectos de una desaceleración del crecimiento monetario sobre la tasa de interés real, la tasa de cambio real, la producción y los precios. Por medio de la contabilidad de innovaciones concluimos que los choques de la tasa de interés real y del crecimiento de la base monetaria fueron los principales causantes de la desinflación.

  13. Steven E. Miller and Dmitri V. Trenin, eds., The Russian Military: Power and Policy, Cambridge, MA: MIT Press, 2004.

    Directory of Open Access Journals (Sweden)

    Mikhail Tsypkin

    2005-10-01

    Full Text Available The Russian military largely went below the radar of Western interest after the disintegration of the Soviet Union.  More than a decade after the creation of the Armed Forces of the Russian Federation, they have become again the object of interest for scholars – this time, both Western and Russian, as demonstrated by the reviewed volume, whose editors assembled a group of extraordinarily knowledgeable experts from Russia and the West.  In his introduction, Steven Miller explains that the purp...

  14. Diagnóstico de síndrome de Miller Fisher tras manifestaciones otorrinolaringológicas

    OpenAIRE

    Santos Gorjón, Pablo; Sánchez Terradillos, Elena; Mingo Sánchez, Eva María; Sánchez-Jara Sánchez, Juan Luis; Martín Hernández, Gonzalo

    2015-01-01

    [ES] Introducción y objetivos: El Síndrome de Miller-Fisher (SMF) es la forma más frecuente entre las formas no clásicas (variantes) del síndrome de Guillain Barré. Se caracteriza por la tríada clásica de oftalmoplejía, ataxia y arreflexia. Material y métodos: Presentamos el caso de un paciente de 19 años que consulta porque tras una faringitis irritativa vírica, desarrolla una inestablidad importante y aparece una disfagia importante incluso para secreciones basales. Se evidencia una marcha...

  15. THE EFFECT OF FIRMS’ SHORT RUN DEPT ON THE PRICE VARIATION OF ASSETS THE MODIGLIANI-MILLER THEORY

    Directory of Open Access Journals (Sweden)

    ERCAN BALDEMİR

    2013-06-01

    Full Text Available It has been seen that the firms increase their short-term debt rates in Turkish economy. However, the stock value of the firms continue to increase in Istanbul Stock Exchange (ISE as well. The aim of this study is to measure whether there is a relationship between the short-term debt rate of the firms and the ISE 100 Index. This kind of an analysis also is also considered as a test for Modigliani-Miller Theorem. Result of article , M-M Theorem  did not valid for Turkey.

  16. [2- to 5-year follow-up of cementless implantable knee joint prosthesis of the Miller-Galante type].

    Science.gov (United States)

    Kienapfel, H; Griss, P; Orth, J; Roloff, K; Malzer, U

    1991-06-01

    Based on a prospective study protocol, the two- to five-year results of the Miller-Galante cementless total knee arthroplasty are presented. Sixty-four implants were placed in 59 patients: 60 implantations were cementless and 4 cemented. Clinically, the scores for pain, range of motion, walking and stair climbing improved significantly. Radiographically, the uncemented components displayed no signs of definite or possible loosening, whereas one of the cemented components was found to be definitely loose. On histological evaluation of the retrieved implants, all components had bone ingrowth.

  17. ´Imperio estético: griegos frente a persas según 300 de Frank Miller

    OpenAIRE

    Díez Platas, Fátima

    2011-01-01

    Este trabajo pretende realizar un análisis iconográfico y estético de la peculiar imagen que ofrece del imperio persa la adaptación cinematográfica de la novela gráfica de Frank Miller 300 (Z. Snyder, 2007). Partiendo de la idea de que la evidente deformación de la representación obedece al giro poético que supone presentar la realidad desde el punto de vista de los espartanos, se examinan las imágenes como el producto de una versión personal, y se exploran las razones a las que ...

  18. A super-high throughput implementation of MD5 algorithm on FPGA%超高吞吐量MD5算法的FPGA实现

    Institute of Scientific and Technical Information of China (English)

    王臣; 袁焱

    2011-01-01

    In this paper, a novel architecture is proposed to increase the performance of MD5 computing in FPGA , which can achieve a super-high throughput. The scheme is based on full-pipeline for MD5 implementation. Moreover, FIFO cache structure is used for data storage and cooperative computing. The results of simulation and implementation show that the scheme can achieve the theoretical upper bound on throughput. And based on the same platform of FPGA, it outperforms the published scheme with best performance in terms of 77% higher throughput.%为了提高MD5算法在FPGA中实现的运算效率,使之达到超高的数据吞吐量,提出了一种新的全流水线架构,用于实现MD5算法.架构中使用了FIFO缓存存储数据,以配合流水线的运算.实验验证其达到了单个MD5运算单元运算吞吐量的理论上限,在相同芯片平台上,超过已发表的MD5运算模块最高吞吐量的77%.

  19. 一种使MD5算法产生更强雪崩效应的方法%Generating stronger avalanche effect in MD5 algorithm

    Institute of Scientific and Technical Information of China (English)

    张鑫彦; 闫德勤

    2010-01-01

    通过研究不同的差分分析对MD5算法的攻击后发现,差分分析攻击之所以可以成功,是因为在MD5算法中改变了明文中一些特定位,而这些特定位的改变在许多轮中最多只影响链接变量的几个位,并且这些小的差分能在随后的多轮操作中得到纠正,从而产生了碰撞.这就说明原MD5算法的雪崩效应不能阻止差分分析的攻击,而为了提高MD5算法的安全性,必须提高其雪崩效应的敏感性.分析结果表明,用动态明文变化函数对MD5算法进行修改,能使其产生更敏感的雪崩效应,以此来有效防止差分分析攻击,提高MD5算法的安全性.

  20. IG Statement: Arthur A. Elkins, Jr., on OIG report Early Warning Report: Main EPA Headquarters Warehouse in Landover, Maryland, Requires Immediate EPA Attention

    Science.gov (United States)

    Statement of Inspector General Arthur A. Elkins, Jr., on the Office of Inspector General (OIG) report Early Warning Report: Main EPA Headquarters Warehouse in Landover, Maryland, Requires Immediate EPA Attention.

  1. North American Regional Security: A Trilateral Framework. By Richard J. Kilroy, Jr., Abelardo Rodriquez Sumano, and Todd S. Hataley, Boulder, CO: Lynne Rienner Press, 2013.

    Directory of Open Access Journals (Sweden)

    Robert Stewart-Ingersoll

    2014-04-01

    Full Text Available North American Regional Security: A Trilateral Framework. By Richard J. Kilroy, Jr., Abelardo Rodriquez Sumano, and Todd S. Hataley, Boulder, CO: Lynne Rienner Press, 2013. ISBN 978-1-58826-854-9.

  2. Efecto del Almacenamiento a Diferentes Temperaturas sobre la Calidad de Tuna Roja (Opuntia ficus indica (L. Miller Effect of the Storage at Different Temperatures on the Quality of Red Prickle Pear (Opuntia ficus indica (L. Miller

    Directory of Open Access Journals (Sweden)

    Carlos E Ochoa

    2012-01-01

    Full Text Available Se estudia el efecto del almacenamiento a diferentes temperaturas sobre la calidad de tuna roja (Opuntia ficus indica (L. Miller, variedad San Martín. El fruto se almacenó a 4±1, 9±2 y 28±2°C para determinar su vida útil. Se realizó semanalmente la caracterización fisicoquímica, enzimática, antioxidante y microbiológica durante el almacenamiento, hasta observar características no aptas para el consumo. Se observó que el tiempo y la temperatura de almacenamiento son factores que afectan de manera significativa (P0,05 a las diferentes temperaturas de almacenamiento. Sin embargo, la actividad antioxidante presentó un aumento significativo con el tiempo.The effect of the storage at different temperatures on the quality of red prickle pear (Opuntia ficus indica (L. Miller San Martín variety. The fruit was stored at 4±1, 9±2, and 28±2°C for determining its shelf life. Once a week, physicochemical, enzymatic, antioxidant and microbiological characteristics were evaluated until fruit showed no edible characteristics. Time and storage temperature were the two parameters that significantly affected (p0.05 during storage time. However, antioxidant capacity presented a significant increase with time.

  3. MD#1182: Calibration of diamond particle detectors in IP6

    CERN Document Server

    Valette, Matthieu; Lindstrom, Bjorn Hans Filip; Wiesner, Christoph

    2017-01-01

    In case of an asynchronous beam dump with a fully filled LHC machine it is expected that all standard ionisation chamber Beam Loss Monitors (IC BLM) around the LHC dumping region in IP6 will be saturated. Diamond Beam Loss Monitors (dBLM) were therefore installed next to the movable dump protection absorber (TCDQ) downstream of the extraction kickers. These detectors allow resolving losses at a nanosecond timescale and with an dynamic range of several orders of magnitude; thus, allowing to know the number of nominal bunches impacting the TCDQ. After a first series of calibrations using asynchronous beam dump tests, an experiment was conducted during MD#1182 to demonstrate the possibility of resolving a nominal bunch hitting the TCDQ. The impact parameter of the bunches on the TCDQ was first scanned using probe bunches with lower intensity then tests were done with nominal bunches (1.1e11 p/bunch) at injection energy. High energy calibration of the losses was also attempted unsuccessfully. Due to different beh...

  4. 76 FR 17672 - Alfred E. Boyce, M.D.; Decision and Order

    Science.gov (United States)

    2011-03-30

    ... Enforcement Administration Alfred E. Boyce, M.D.; Decision and Order On August 12, 2010, Administrative Law....100(b) and 0.104, I order that DEA Certificate of Registration, FB0003943, issued to Alfred E. Boyce, M.D., be, and it hereby is, revoked. I further order that any pending application of Alfred E....

  5. 76 FR 50950 - Drawbridge Operation Regulation; Isle of Wight (Sinepuxent) Bay, Ocean City, MD

    Science.gov (United States)

    2011-08-17

    ... (Sinepuxent) Bay, Ocean City, MD AGENCY: Coast Guard, DHS. ACTION: Notice of proposed rulemaking. SUMMARY: The... of Wight (Sinepuxent) Bay, mile 0.5, at Ocean City, MD. The proposed change will alter the dates the... will then become highlighted in blue. In the ``Document Type'' drop down menu select ``Proposed...

  6. 75 FR 41789 - Special Local Regulations for Marine Events; Patuxent River, Solomons, MD

    Science.gov (United States)

    2010-07-19

    ... River, Solomons, MD AGENCY: Coast Guard, DHS. ACTION: Supplemental notice of proposed rulemaking... Challenge'' power boat races, a marine event to be held on the waters of the Patuxent River, near Solomons... for Marine Events; Patuxent River, Solomons, MD'' in the Federal Register (75 FR 111). The NPRM stated...

  7. 76 FR 48898 - Robert Leigh Kale, M.D., Decision and Order

    Science.gov (United States)

    2011-08-09

    ... Enforcement Administration Robert Leigh Kale, M.D., Decision and Order On September 9, 2010, the Deputy... Show Cause to Robert Leigh Kale, M.D. (Registrant), of Fort Smith, Arkansas. ] The Show Cause Order....100(b) and 0.104, I order that DEA Certificate of Registration, BK9514375, issued to Robert Leigh...

  8. HST observations of the nebula around the central compact object in the Vela Jr. supernova remnant

    Science.gov (United States)

    Mignani, R. P.; de Luca, A.; Pellizzoni, A.

    2009-12-01

    Context: A handful of young (a few thousand years) supernova remnants (SNRs) host point-like X-ray sources, dubbed central compact objects (CCOs), which are thought to be radio-silent isolated neutron stars formed by the supernova explosion. So far, no CCO has been firmly detected at other wavelengths. However, ground-based observation in the Hα band detected a nebula around CXO J085201.4-461753, the CCO in the Vela Jr. SNR. The nebula has also been detected in deep R-band observations performed with the Very Large Telescope (VLT). Interestingly, both its extension and its flux in the R band are consistent with those measured in Hα, suggesting that the nebula spectrum is dominated by line emission, possibly produced by a velocity-driven bow-shock in the interstellar medium (ISM) or by its photo-ionisation from the neutron star. Aims: The aim of this work is to resolve the morphology of the Hα nebula around the CCO to verify the proposed interpretations. Methods: We performed high-resolution imaging observations of the nebula with the Wide Field Planetary Camera 2 (WFPC2) of the Hubble Space Telescope (HST) through the 656N filter, almost exactly centred on the rest wavelength of the Hα line. Results: Surprisingly enough, we did not detect the nebula in our WFPC2 image down to a 3 σ flux limit of ~3 × 10-15 erg cm-2 s-1. This limit is a factor of 10 fainter than the nebula flux measured in the discovery ground-based observations which were, however, performed with redder and broader Hα filters. Conclusions: The non-detection of the nebula in the narrower and bluer WFPC2 656N filter suggests that the peak of the emission might actually be at longer wavelengths. One possibility, compatible with the bow-shock scenario only, is that the Hα line is red-shifted by ~10-60 Å due to the neutron star motion with a radial velocity 450 ⪉ Vr ⪉ 2700 km s-1. The other possibility is that the nebula is a knot of [NII] emission (λ = 6583.6 Å) unrelated to CXO J085201

  9. H5MD: a structured, efficient, and portable file format for molecular data

    CERN Document Server

    de Buyl, Pierre; Höfling, Felix

    2013-01-01

    We propose a new open file format named "H5MD" for storing molecular simulation data such as trajectories of particle positions and velocities as well as thermodynamic observables that are tracked during the course of the simulation. H5MD files are HDF5 (Hierarchical Data Format) files with a specific hierarchy and naming scheme. Thus, H5MD inherits many benefits of HDF5, e.g., structured layout of multi-dimensional data sets, data compression, fast and parallel I/O, and portability across many programming languages and hardware platforms. H5MD files are self-contained, and foster the reproducibility of scientific data and the interchange of data between researchers using different simulation programs and analysis software. In addition, the H5MD specification can serve for other kinds of data (e.g. experimental data) and is extensible to supplemental data without breaking the compliance of the file to the specification.

  10. PHP中的MD5加密机制探究

    Institute of Scientific and Technical Information of China (English)

    党长青

    2014-01-01

    MD5广泛用于加密和解密技术上。现阶段,存在两种加密方式,双向加密和单向加密。MD5是在Web应用程序中最常用的密码加密算法。由于MD5是不可逆的,因而经过MD5计算得到后的密文,不能通过逆向算法得到原文。在PHP应用程序中使用MD5加密文本密码的初衷,就是为了防止数据库中保存的密码不幸泄露后被直接获得。

  11. Primordial Synthesis of Amines and Amino Acids in a 1958 Miller H2S-Rich Spark Discharge Experiment

    Science.gov (United States)

    Parker, Eric T.; Cleaves, Henderson J.; Dworkin, Jason P.; Glavin, Daniel P.; Callahan, Michael; Aubrey, Andrew; Lazcano, Antonio; Bada, Jeffrey L.

    2011-01-01

    Archived samples from a previously unreported 1958 Stanley Miller electric discharge experiment containing hydrogen sulfide (H2S) were recently discovered and analyzed using high-performance liquid chromatography and time-of-flight mass spectrometry. We report here the detection and quantification of primary amine-containing compounds in the original sample residues, which were produced via spark discharge using a gaseous mixture of H2S, CH4, NH3, and CO2. A total of 23 amino acids and 4 amines, including 7 organosulfur compounds, were detected in these samples. The major amino acids with chiral centers are racemic within the accuracy of the measurements, indicating that they are not contaminants introduced during sample storage. This experiment marks the first synthesis of sulfur amino acids from spark discharge experiments designed to imitate primordia! environments. The relative yield of some amino acids, in particular the isomers of aminobutyric acid, are the highest ever found in a spark discharge experiment. The simulated primordial conditions used by Miller may serve as a model for early volcanic plume chemistry and provide insight to the possible roles such plumes may have played in abiotic organic synthesis. Additionally, the overall abundances of the synthesized amino acids in the presence of H2S are very similar to the abundances found in some carbonaceous meteorites, suggesting that H2S may have played an important role in prebiotic reactions in early solar system environments.

  12. Counterpoint to “What Is an Epileptic Seizure?” By D’Ambrosio and Miller

    Science.gov (United States)

    Dudek, F Edward; Bertram, Edward H

    2010-01-01

    D’Ambrosio and Miller argue that brief (i.e., one to a few seconds), rhythmic electrographic events accompanied by behavioral arrest, which they have observed in rats after lateral fluid percussion (i.e., in an animal model of traumatic brain injury), should be considered seizures in this model of posttraumatic epilepsy (1). A counter argument is that these events are not characteristic of the seizures seen clinically in posttraumatic epilepsy or in other forms of acquired epilepsy. Furthermore, several types of brief, rhythmic activity can be recorded in the electroencephalogram (EEG) of animals and humans without epilepsy. One cannot exclude the possibility that such events represent normal electrical activity, which may (or even may not) occur more often after brain injury. Thus, caution is required. In this counterpoint to “What Is an Epileptic Seizure?” by D’Ambrosio and Miller, the assertion is made that experimental studies on animal models of acquired epilepsy that claim electrographic events to be seizures, when the possibility exists that they may not be seizures characteristic of human acquired epilepsy, could be counterproductive, since research resources could be focused on animal models that may not actually demonstrate acquired epilepsy. PMID:20697504

  13. The formation of organic molecules in solar system environments: The Miller-Urey Experiment in Space preflight overview

    Science.gov (United States)

    Kotler, J.; Ehrenfreund, P.; Martins, Z.; Ricco, A.; Blum, J.; Schraepler, R.; van Dongen, J.; Palmans, A.; Sephton, M.; Cleaves, H. J.

    2011-12-01

    The Miller-Urey Experiment in space (MUE) will investigate the formation of prebiotic organic compounds in the early solar system environment when it is sent to, and later retrieved from, the International Space Station in 2012. The dynamic environment of the solar nebula with the simultaneous presence of gas, particles, and energetic processes, including shock waves, electrical discharges, and radiation may trigger a rich organic chemistry leading to organic molecules. Two gas mixture compositions (CH4, NH3, H2 and N2, H2, CO) will be tested and subjected to continuous spark discharges for 48, 96, and 192 hours. Silicate particles will serve as surfaces on which thin water ice mantles can accrete. The experiment will be performed at low temperatures (-5 °C), slowing hydrolysis and improving chances of detection of initial products, intermediates and their abundances. Conducting the Miller-Urey experiment in the space environment (microgravity) allows us to simulate conditions that could have prevailed in the low gravity, energetic early solar nebula and provides insights into the chemical pathways that may occur as planetary systems form.

  14. CERN Library | Arthur I. Miller presents "Colliding worlds: How Cutting-Edge Science Is Redefining Contemporary Art" | 21 October

    CERN Multimedia

    2014-01-01

    In recent decades, an exciting new art movement has emerged in which artists illuminate the latest advances in science.   Some of their provocative creations - a live rabbit implanted with the fluorescent gene of a jellyfish, a gigantic glass-and-chrome sculpture of the Big Bang itself - can be seen in traditional art museums and magazines, while others are being made by leading designers at Pixar, Google's Creative Lab and the MIT Media Lab. Arthur I. Miller takes readers on a wild journey to explore this new frontier. From the movement's origins a century ago - when Einstein shaped Cubism and X-rays affected fine photography - to the latest discoveries of biotechnology, cosmology and quantum physics, Miller shows how today's artists and designers are producing work at the cutting edge of science. Tuesday, 21 October 2014 at 14:30 in the Library, Bldg. 52 1-052 https://indico.cern.ch/event/346299/ *Coffee will be served from 2 p.m.* "Colliding Worlds: How Cutt...

  15. The effects of discontinuities in the Betts Miller cumulus convection scheme on four-dimensional variational data assimilation

    Science.gov (United States)

    Zupanski, Dušanka

    1993-10-01

    A tangent linear and an adjoint of the large-scale precipitation and the cumulus convection processes in the National Meteorological Center's NMC/ETA regional forecast model are developed. The effects of discontinuities in the Betts Miller cumulus convection scheme are examined and applicability of derivative minimization methods in four-dimensional variational (4D VAR) data assimilation is considered. It is demonstrated that discontinuities present in the control Betts Miller cumulus convection scheme increase linearization errors to a large extent and have adverse effects on 4D VAR data assimilation. In the experiments performed, discontinuities in the cumulus convection scheme have the most serious effect in low layers. These problems can be reduced by modifying the scheme to make it more continuous in low layers. Positive effects of inclusion of cumulus convection in 4D VAR data assimilation are found in upper layers, especially in humidity fields. The "observations" used are optimal interpolation analyses of temperature, surface pressure, wind and specific humidity. By inclusion of other data, more closely related to the convective processes, such as precipitation and clouds, more benefits should be expected. Even with the difficulties caused by discontinuities, derivative minimization techniques appear to work for the data assimilation problems. In order to get more general conclusions, more experiments are needed with different synoptic situations. The inclusion of other important physical processes such as radiation, surface friction and turbulence in the forecast and the corresponding adjoint models could alter the results since they may reinforce the effects of discontinuities.

  16. Schwann cells are activated by ATP released from neurons in an in vitro cellular model of Miller Fisher syndrome

    Directory of Open Access Journals (Sweden)

    Umberto Rodella

    2017-05-01

    Full Text Available The neuromuscular junction is exposed to different types of insult, including mechanical trauma, toxins and autoimmune antibodies and, accordingly, has retained through evolution a remarkable ability to regenerate. Regeneration is driven by multiple signals that are exchanged among the cellular components of the junction. These signals are largely unknown. Miller Fisher syndrome is a variant of Guillain–Barré syndrome caused by autoimmune antibodies specific for epitopes of peripheral axon terminals. Using an animal model of Miller Fisher syndrome, we recently reported that a monoclonal anti-polysialoganglioside GQ1b antibody plus complement damages nerve terminals with production of mitochondrial hydrogen peroxide, which activates Schwann cells. Several additional signaling molecules are likely to be involved in the activation of the regeneration program in these cells. Using an in vitro cellular model consisting of co-cultured primary neurons and Schwann cells, we found that ATP is released by neurons injured by the anti-GQ1b antibody plus complement. Neuron-derived ATP acts as an alarm messenger for Schwann cells, where it induces the activation of intracellular pathways, including calcium signaling, cAMP and CREB, which, in turn, produce signals that promote nerve regeneration. These results contribute to defining the cross-talk taking place at the neuromuscular junction when it is attacked by anti-gangliosides autoantibodies plus complement, which is crucial for nerve regeneration and is also likely to be important in other peripheral neuropathies.

  17. Md1 and Rp105 regulate innate immunity and viral resistance in zebrafish.

    Science.gov (United States)

    Candel, Sergio; Sepulcre, María P; Espín-Palazón, Raquel; Tyrkalska, Sylwia D; de Oliveira, Sofía; Meseguer, José; Mulero, Victoriano

    2015-06-01

    TLR4 was the first TLR family member identified in mammals and is responsible for the activation of the immune response by bacterial LPS. Later, MD1 and RP105 were shown to form complexes that directly interact with the MD2-TLR4 complex, acting as physiological negative regulators of LPS signaling. Despite the general conservation of various TLR families from fish to mammals, several differences can be appreciated, such as the high tolerance of fish to LPS, the absence of the crucial accessory molecules Md2 and Cd14 for Tlr4 signaling in fish, the absence of Tlr4 in some fish species, and the confirmation that LPS does not signal through Tlr4 in zebrafish. The present study has identified the Rp105 and Md1 homologs in zebrafish, confirming (i) Rp105 and Tlr4 evolved from a common ancestor before the divergence between fish and tetrapods and (ii) the presence of Md1 in teleost fish and the lack of Md2, suggesting that the divergence of these accessory molecules occurred in the tetrapod lineage. Biochemical and functional studies indicate that Md1 binds both Rp105 and Tlr4 in zebrafish. Genetic inhibition of zebrafish Md1 and Rp105 reveals that Md1 or Rp105 deficiency impairs the expression of genes encoding pro-inflammatory and antiviral molecules, leading to increased susceptibility to viral infection. These results shed light on the evolutionary history of Md1 and Rp105 and uncover a previously unappreciated function of these molecules in the regulation of innate immunity.

  18. ESTUDO DA GERMINAÇÃO DE SEMENTES DE LAVANDA (Lavandula angustifolia Miller

    Directory of Open Access Journals (Sweden)

    E.M. AOYAMA

    1996-05-01

    Full Text Available Com o objetivo de estudar os efeitos do ácido giberélico, do efeito luz/escuro e do pré-resfriamento sobre a germinação de sementes de lavanda (Lavandula angustifolia Miller, empregou-se o delineamento experimental inteiramente casualizado, com cinco repetições de 30 sementes cada, e os seguintes tratamentos: testemunha; GA3 100 ppm; GA3 200 ppm; escuro; GA3 100 e 200 ppm + 48 h de pré-resfriamento e GA3 100 e 200 ppm + 7 dias de pré-resfriamento. As sementes de lavanda foram pré-embebidas por 18 horas nas soluções de GA3 e em água destilada e depois colocadas em gerbox, com papel de filtro umedecido com água destilada. Nos tratamentos com pré-resfriamento as sementes foram mantidas em câmara fria por 48 horas e 7 dias à temperatura de 5° C; posteriormente, foram transferidas para o germinador, sob luz branca contínua à temperatura constante de 25°C. A contagem das sementes foi realizada de 2 em 2 dias até completar 30 dias de teste. Para a avaliação dos efeitos dos tratamentos sobre a germinação das sementes foram realizadas as seguintes observações: a porcentagem de sementes germinadas e b tempo médio de germinação (expresso em dias. A partir dos resultados obtidos pode-se verificar que os tratamentos com GA3, em conjunto ou não com pré-resfriamento, aumentaram significativamente a porcentagem de germinação, além de acelerar tal processo.To study the effects of gibbellic acid, of the light/darkness and of pre-freezing on the germination of lavender seeds, a randomized experiment was used, with five replications of 30 seeds, with the following treatments: control, GA3 100 ppm, GA3 200 ppm, darkness, GA3 100 and 200 ppm + 48 h pre-freezing and GA3 100 and 200 ppm + 7 days of pre-freezing. The lavender seeds were pre-soaked during 18 hours in GA3 and destilated water solutions, and thereafter placed in gerbox, using moistened filter paper. In the pre-freezing treatments the seeds were kept in a refrigerator for

  19. Electroporation of archaeal lipid membranes using MD simulations.

    Science.gov (United States)

    Polak, Andraž; Tarek, Mounir; Tomšič, Matija; Valant, Janez; Ulrih, Nataša Poklar; Jamnik, Andrej; Kramar, Peter; Miklavčič, Damijan

    2014-12-01

    Molecular dynamics (MD) simulations were used to investigate the electroporation of archaeal lipid bilayers when subjected to high transmembrane voltages induced by a charge imbalance, mimicking therefore millisecond electric pulse experiments. The structural characteristics of the bilayer, a 9:91 mol% 2,3-di-O-sesterterpanyl-sn-glicerol-1-phospho-myo-inositol (AI) and 2,3-di-O-sesterterpanyl-sn-glicerol-1-phospho-1'(2'-O-α-D-glucosyl)-myo-inositol (AGI) were compared to small angle X-ray scattering data. A rather good agreement of the electron density profiles at temperatures of 298 and 343 K was found assessing therefore the validity of the protocols and force fields used in simulations. Compared to dipalmitoyl-phosphatidylcholine (DPPC), the electroporation threshold for the bilayer was found to increase from ~2 V to 4.3 V at 323 K, and to 5.2 V at 298 K. Comparing the electroporation thresholds of the archaeal lipids to those of simple diphytanoyl-phosphatidylcholine (DPhPC) bilayers (2.5 V at 323 K) allowed one to trace back the stability of the membranes to the structure of their lipid head groups. Addition of DPPC in amounts of 50 mol% to the archaeal lipid bilayers decreases their stability and lowers the electroporation thresholds to 3.8 V and 4.1 V at respectively 323 and 298 K. The present study therefore shows how membrane compositions can be selected to cover a wide range of responses to electric stimuli. This provides new routes for the design of liposomes that can be efficiently used as drug delivery carriers, as the selection of their composition allows one to tune in their electroporation threshold for subsequent release of their load.

  20. 77 FR 67671 - Larry Elbert Perry, M.D.; Decision and Order

    Science.gov (United States)

    2012-11-13

    ... Law Judge John J. Mulrooney, Jr., issued the attached Recommended Decision. Neither party filed... Chief Administrative Law Judge John J. Mulrooney II. On May 4, 2012, the Deputy Assistant Administrator... Cir. 1989); Thomas E. Johnston, 45 Fed. Reg. 72311 (1980). The Controlled Substances Act (CSA...

  1. O drama social, o herói trágico e o "sonho americano" em a morte de um caixeiro-viajante de Arthur Miller

    OpenAIRE

    Poppelaars, Antonius Gerardus Maria

    2016-01-01

    A Morte de um Caixeiro-Viajante (1949) de Arthur Miller tem como protagonista Willy Loman, um simples vendedor fracassado da classe média baixa. Um homem comum como Willy Loman pode ser considerado como herói trágico? Existe ainda tragicidade no drama moderno? Seria o lado sombrio do “sonho americano” a falha trágica externa para a queda de Loman? O objetivo do estudo da peça de Arthur Miller, A Morte de um Caixeiro-Viajante, está centrado na possibilidade do protagonista, Will...

  2. Efek Pemberian Ekstrak Lidah Buaya (Aloe Barbadensis Miller pada Soket Gigi terhadap Kepadatan Serabut Kolagen Pasca Ekstraksi Gigi Marmut (Cavia Porcellus

    Directory of Open Access Journals (Sweden)

    Fatma Yuza

    2014-12-01

    sockets density of collagen were observed using light microscope 400x magnification. Analyzing data is done by Kruskal-Wallis test followed by Post Hoc test using the Mann-Whitney test for comparing collagen density between groups. Statistically results between groups showed that the extract of 90% Aloe barbadensis Miller affected the formation of collagen fibers when compared to the control group (p <0.05 on day 7 after tooth extraction of guinea pig. The conclusion of this study was 90% Aloe barbadensis Miller extract increased the density of collagen fibers from the tooth socket seven days after tooth extraction of guinea pig.

  3. Daisy, A Victim of Prejudice in Intercultural Communication--An Analy-sis of Daisy’s Tragic Destiny in Henry James’Daisy Miller

    Institute of Scientific and Technical Information of China (English)

    李明

    2014-01-01

    Daisy Miller, among Henry James’masterpieces, is the novella which won him international fame. As some critics have analyzed, Daisy is a victim of the values of the Old World. In the author’s opinion, Daisy’s tragedy should be partly attrib-uted to prejudice, which impedes the international communication between the newly wealthy Americans and the Europeanized Americans. In this sense, this paper focuses on an analysis of three forms of prejudice in Daisy Miller and tries to interpret Daisy’s tragic destiny from the perspective of intercultural communication.

  4. Oliver Wendell Holmes Jr. y su obra: Una fusión sistemático-existencial

    OpenAIRE

    Portela Valentín, Orlando Guillermo

    2016-01-01

    607 p. La presente Tesis, analiza las ideas filosófico-jurídicas del Juez Oliver Wendell Holmes, Jr. Y la manera en que dichas ideas influyen en las diferentes escuelas modernas del pensamiento jurídico norteamericano. En particular se analiza su visión instrumental del Derecho y la forma en que éste se relaciona con la moral, la historia y el poder político y económico, todas estas ideas que marcan el pensamiento filosófico-jurídico norteamericano en la modernidad.Para alcanzar este propó...

  5. Comparative assessment of cyclic J-R curve determination by different methods in a pressure vessel steel

    Science.gov (United States)

    Chowdhury, Tamshuk; Sivaprasad, S.; Bar, H. N.; Tarafder, S.; Bandyopadhyay, N. R.

    2016-04-01

    Cyclic J-R behaviour of a reactor pressure vessel steel using different methods available in literature has been examined to identify the best suitable method for cyclic fracture problems. Crack opening point was determined by moving average method. The η factor was experimentally determined for cyclic loading conditions and found to be similar to that of ASTM value. Analyses showed that adopting a procedure analogous to the ASTM standard for monotonic fracture is reasonable for cyclic fracture problems, and makes the comparison to monotonic fracture results straightforward.

  6. Apple F-box Protein MdMAX2 Regulates Plant Photomorphogenesis and Stress Response

    Directory of Open Access Journals (Sweden)

    Jian-Ping An

    2016-11-01

    Full Text Available MAX2 (MORE AXILLARY GROWTH2 is involved in diverse physiological processes, including photomorphogenesis, the abiotic stress response, as well as karrikin and strigolactone signaling-mediated shoot branching. In this study, MdMAX2, an F-box protein that is a homolog of Arabidopsis MAX2, was identified and characterized. Overexpression of MdMAX2 in apple calli enhanced the accumulation of anthocyanin. Ectopic expression of MdMAX2 in Arabidopsis exhibited photomorphogenesis phenotypes, including increased anthocyanin content and decreased hypocotyl length. Further study indicated that MdMAX2 might promote plant photomorphogenesis by affecting the auxin signaling as well as other plant hormones. Transcripts of MdMAX2 were noticeably up-regulated in response to NaCl and Mannitol treatments. Moreover, compared with the wild type, the MdMAX2-overexpressing apple calli and Arabidopsis exhibited increased tolerance to salt and drought stresses. Taken together, these results suggest that MdMAX2 plays a positive regulatory role in plant photomorphogenesis and stress response.

  7. PTX3 binds MD-2 and promotes TRIF-dependent immune protection in aspergillosis.

    Science.gov (United States)

    Bozza, Silvia; Campo, Silvia; Arseni, Brunilde; Inforzato, Antonio; Ragnar, Lindstedt; Bottazzi, Barbara; Mantovani, Alberto; Moretti, Silvia; Oikonomous, Vasileios; De Santis, Rita; Carvalho, Agostinho; Salvatori, Giovanni; Romani, Luigina

    2014-09-01

    The long pentraxin 3 (PTX3) modulates different effector pathways involved in innate resistance to Aspergillus fumigatus, including complement activation or promotion of phagocytosis by interacting with FcγRs. However, whether and how TLRs modulate PTX3 mediates antifungal resistance is not known. In this study, we demonstrate that PTX3 binds myeloid differentiation protein 2 (MD-2) in vitro and exerts its protective antifungal activity in vivo through TLR4/MD-2-mediated signaling. Similar to Tlr4(-/-) mice, Md2(-/-) mice displayed high susceptibility to pulmonary aspergillosis, a phenotype associated with a proinflammatory cytokine profile and impaired antifungal activity of polymorphonuclear neutrophils. Treating Md2(-/-) mice with PTX3 failed to confer immune protection against the fungus, whereas adoptive transfer of MD-2-competent polymorphonuclear neutrophils restored it. Mechanistically, engagement of MD-2 by PTX3-opsonized Aspergillus conidia activated the TLR4/Toll/IL-1R domain-containing adapter inducing IFN-β-dependent signaling pathway converging on IL-10. Thus, we have identified a novel receptor mechanism, involving the TLR4/MD-2/Toll/IL-1R domain-containing adapter inducing IFN-β-mediated signaling, whereby PTX3 elicits antifungal resistance with limited immunopathology in A. fumigatus infection. Copyright © 2014 by The American Association of Immunologists, Inc.

  8. The Design of MD5 Algorithm against Exhaustion Code-breaking and Its Realization%MD5算法防穷举(冲撞)破译的设计及其实现

    Institute of Scientific and Technical Information of China (English)

    廖思周

    2006-01-01

    在对MD5算法做简单介绍的基础上,针对攻击者拥有巨大密码字典、原文/密文对照数据库,设计了MD5变换算法,是对现有的MD5算法的延伸,大大提高了现成MD5密文的安全性.

  9. MD5算法及在用户口令加密应用中的改进%The Improved MD5 Algorithm in the Encryption of User Passwords

    Institute of Scientific and Technical Information of China (English)

    高洪波; 马素萍

    2010-01-01

    MD5是一种非常优秀的加密算法,曾被大量公司和个人广泛使用.但随着科学技术的发展,MD5牢不可破的神话逐渐破灭.基于此,在分析MD5加密算法及其弱点的前提下,探讨了MD5的改进算法.

  10. Characterization of an Autophagy-related Gene MdATG8i from apple

    Directory of Open Access Journals (Sweden)

    Ping eWang

    2016-05-01

    Full Text Available Nutrient deficiencies restrict apple (Malus sp. tree growth and productivity in Northwest China. The process of autophagy, a conserved degradation pathway in eukaryotic cells, has important roles in nutrient-recycling and helps improve plant performance during periods of nutrient-starvation. Little is known about the functioning of autophagy-related genes (ATGs in apple. In this study, one of the ATG8 gene family members MdATG8i was isolated from M. domestica. MdATG8i has conserved putative tubulin binding sites and ATG7 interaction domains. A 1865-bp promoter region cloned from apple genome DNA was predicated to have cis-regulatory elements responsive to light, environmental stresses and hormones. MdATG8i transcriptions were induced in response to leaf senescence, nitrogen depletion, and oxidative stress. At cellular level, MdATG8i protein was expressed in the nucleus and cytoplasm of onion epidermal cells. Yeast two-hybrid tests showed that MdATG8i could interact with MdATG7a and MdATG7b. In Arabidopsis, its heterologous expression was associated with enhanced vegetative growth, leaf senescence, and tolerance to nitrogen- and carbon-starvation. MdATG8i-overexpressing ‘Orin’ apple callus lines also displayed improved tolerance to nutrient-limited conditions. Our results demonstrate that MdATG8i protein could function in autophagy in a conserved way, as a positive regulator in the response to nutrient-starvation.

  11. Osmotically and thermally isolated forward osmosis-membrane distillation (fo-md) integrated module for water treatment applications

    KAUST Repository

    Ghaffour, Noreddine

    2016-09-01

    An integrated forward osmosis-membrane distillation (FO-MD) module and systems and methods incorporating the module is disclosed providing higher efficiencies and using less energy. The FO-MD module is osmotically and thermally isolated. The isolation can prevent mixing of FO draw solution/FO permeate and MD feed, and minimize dilution of FO draw solution and cooling of MD feed. The module provides MD feed solution and FO draw solution streams that flow in the same module but are separated by an isolation barrier. The osmotically and thermally isolated FO-MD integrated module, systems and methods offer higher driving forces of both FO and MD processes, higher recovery, and wider application than previously proposed hybrid FO- MD systems.

  12. Milestone report on MD potential development for uranium silicide

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Jianguo [Idaho National Lab. (INL), Idaho Falls, ID (United States). Fuel Modeling and Simulation Dept.; Zhang, Yongfeng [Idaho National Lab. (INL), Idaho Falls, ID (United States). Fuel Modeling and Simulation Dept.; Hales, Jason Dean [Idaho National Lab. (INL), Idaho Falls, ID (United States). Fuel Modeling and Simulation Dept.

    2016-03-01

    This report summarizes the progress on the interatomic potential development of triuranium-disilicide (U3Si2) for molecular dynamics (MD) simulations. The development is based on the Tersoff type potentials for single element U and Si. The Si potential is taken from the literature and a Tersoff type U potential is developed in this project. With the primary focus on the U3Si2 phase, some other U-Si systems such as U3Si are also included as a test of the transferability of the potentials for binary U-Si phases. Based on the potentials for unary U and Si, two sets of parameters for the binary U-Si system are developed using the Tersoff mixing rules and the cross-term fitting, respectively. The cross-term potential is found to give better results on the enthalpy of formation, lattice constants and elastic constants than those produced by the Tersoff mixing potential, with the reference data taken from either experiments or density functional theory (DFT) calculations. In particular, the results on the formation enthalpy and lattice constants for the U3Si2 phase and lattice constants for the high temperature U3Si (h-U3Si) phase generated by the cross-term potential agree well with experimental data. Reasonable agreements are also reached on the elastic constants of U3Si2, on the formation enthalpy for the low temperature U3Si (m-U3Si) and h-U3Si phases, and on the lattice constants of m-U3Si phase. All these phases are predicted to be mechanically stable. The unary U potential is tested for three metallic U phases (α, β, γ). The potential is found capable to predict the cohesive energies well against experimental data for all three phases. It matches reasonably with previous experiments on the lattice constants and elastic constants of αU.

  13. The core competencies of James Marion Sims, MD.

    Science.gov (United States)

    Straughn, J Michael; Gandy, Roy E; Rodning, Charles B

    2012-07-01

    The concept of core competencies in graduate medical education was introduced by the Accreditation Council for Graduate Medical Education of the American Medical Association to semiquantitatively assess the professional performance of students, residents, practitioners, and faculty. Many aspects of the career of J. Marion Sims, MD, are exemplary of those core competencies: MEDICAL KNOWLEDGE: Author of the first American textbook related to gynecology. MEDICAL CARE: Innovator of the Sims' Vaginal Speculum, Sims' Position, Sims' Test, and vesico-/rectovaginal fistulorrhaphy; advocated abdominal exploration for penetrating wounds; performed the first cholecystostomy. PROFESSIONALISM: Served as President of the New York Academy of Medicine, the American Medical Association, and the American Gynecologic Society. INTERPERSONAL RELATIONSHIPS/COMMUNICATION: Cared for the indigent, hearthless, indentured, disenfranchised; served as consulting surgeon to the Empress Eugénie (France), the Duchess of Hamilton (Scotland), the Empress of Austria, and other royalty of the aristocratic Houses of Europe; accorded the National Order of the Legion of Honor. PRACTICE-BASED LEARNING: Introduction of silver wire sutures; adoption of the principles of asepsis/antisepsis; adoption of the principles of general anesthesia. SYSTEMS-BASED PRACTICE: Established the Woman's Hospital, New York City, New York, the predecessor of the Memorial Sloan-Kettering Center for the Treatment of Cancer and Allied Diseases; organized the Anglo-American Ambulance Corps under the patronage of Napoleon III. What led him to a life of clinical and humanitarian service? First, he was determined to succeed. His formal medical/surgical education was perhaps the best available to North Americans during that era. Second, he was courageous in experimentation and innovation, applying new developments in operative technique, asepsis/antisepsis, and general anesthesia. Third, his curiosity was not burdened by rigid

  14. Classification of 5-Dimensional MD-Algebras Having Non-Commutative Derived Ideals

    CERN Document Server

    Vu, Le Anh; Nghia, Tran Thi Hieu

    2011-01-01

    The paper presents a subclass of the class of MD5-algebras and MD5-groups, i.e. five dimensional solvable Lie algebras and Lie groups such that their orbits in the co-adjoint representation (K-orbits) are orbits of zero or maximal dimension. The main result of the paper is the classification up to an isomorphism of all MD5-algebras with the non-commutative derived ideal. With this result, we have the complete classification of 5-dimensional solvable Lie algebras.

  15. MD5算法应用失败的思考

    Institute of Scientific and Technical Information of China (English)

    TC-XB

    2007-01-01

    MD5算法作为一种高强度的加密算法,被广泛的应用于软件的注册算法中。但是需要指明的是.尽管MD5本身非常强大.但是如果应用不当,那么对软件的保护效果是很难令人满意的。下面我就先说一种最常见的MD5应用失败的形式。

  16. Molecular Cloning and Expression Analysis of a Hexokinase Gene, MdHXK1 in Apple

    Directory of Open Access Journals (Sweden)

    Jin Zhao

    2016-03-01

    Full Text Available A hexokinase gene named MdHXK1 (MDP0000309677 was cloned from ‘Gala’ apple (Malus × domestica Borkh.. Sequence analysis showed that the MdHXK1 gene was 1 497 bp long and encoded 499 amino acids. The predicted molecular mass of this protein was 54.05 kD, and the pI was 5.76. A phylogenetic tree indicated apple MdHXK1 exhibited the highest sequence similarity to Pyrus bretschneideri PbHXK1. Analysis of the functional domain showed that the MdHXK1 protein included two conserved kinase domains. The prediction of subcellular localization suggested that the MdHXK1 protein was mainly localized in the cytoplasm. There was an indication that MdHXK1 existed as one copy in the apple genome by Southern blotting. Silico analysis suggested that the promoter sequence contained several typical cis-acting elements, including defense, sugar signaling and phytohormone responsive elements. Quantitative real-time PCR analysis demonstrated that the MdHXK1 gene was mainly expressed in stem and flower tissues. During the development of apple fruits, the expression of the MdHXK1 gene initially increased and then decreased. The changes on Glc phosphorylation relative activity and glucose concentration showed the same trend. In addition, the expression of this gene was induced by salt stress, low temperature, and abscisic acid (ABA. Finally, we obtained and purified the fused MdHXK1 protein by recombinant prokaryotic expression. Studies have demonstrated that MdHXK1 may participate in sugar metabolism in apple fruits. Enzyme encoded by MdHXK1 is a key factor in the mediation of sugar accumulation. Recently, researchers on hexokinase at home and abroad mainly focused on model plants, such as Arabidopsis, tobacco and rice, but orchard fruit like apple were underresearched. Our research established the foundation for the further study of the functions of MdHXK1.

  17. Lactobacillus farciminis MD, a newer strain with potential for bacteriocin and antibiotic assay.

    Science.gov (United States)

    Halami, P M; Chandrashekar, A; Nand, K

    2000-03-01

    A native isolate Lactobacillus farciminis MD isolated from fermenting mushroom exhibited a high degree of sensitivity to the majority of the bacteriocins produced by strains of lactobacilli, leuconostoc and pediococci. Also, the efficacy of Lact. farciminis MD as a sensitive strain for antibiotic assay was established against different antibiotics including ampicillin, cefazoline, chloramphenicol and nitrofurantoin at concentrations of 30 microg each, showing an inhibition zone of 30 mm diameter. The high degree of sensitivity towards bacteriocins and antibiotics provide potential for the exploitation of Lact. farciminis MD in establishing very well-defined bacteriocin producers.

  18. Application of MD5 Algorithm in Office Automation System%MD5算法在办公自动化系统中的应用

    Institute of Scientific and Technical Information of China (English)

    张智发

    2008-01-01

    该文对办公自动化系统面临的风险进行了分析,介绍了MD5算法的特点和原理,把MD5算法应用于办公自动化系统中,解决了密码保护、信息完整性验证和数字签名等安全问题, 并给出了具体实现方法.

  19. 一种基于MD5算法的B/S通信加密系统%A MD5-based B/S communication encryption system

    Institute of Scientific and Technical Information of China (English)

    申甲

    2010-01-01

    随着网络的全面应用,以Web方式对数据进行操作的安全问题日益突出.本文针对目前广泛应用的MD5(Message Digest 5)加密算法,深入分析了MD5算法加密原理及实现过程,并利用该算法设计实现一种基于B/S(Browser/Server)方式的通信加密系统,达到了信息保密的要求.

  20. 75 FR 68970 - Amendment of Using Agency for Restricted Areas R-4002, R-4005, R-4006 and R-4007; MD

    Science.gov (United States)

    2010-11-10

    ... Restricted Areas R-4002, R-4005, R- 4006 and R-4007; MD AGENCY: Federal Aviation Administration (FAA), DOT... restricted areas R-4002, Bloodsworth Island, MD; and R-4005, R-4006 and R-4007, Patuxent River, MD to ``U.S... areas R-4002, R-4005, R-4006 and R-4007 in Maryland, in order to reflect the correct......