WorldWideScience

Sample records for iter candidate structural

  1. Compatibility of ITER candidate structural materials with static gallium

    Energy Technology Data Exchange (ETDEWEB)

    Luebbers, P.R.; Michaud, W.F.; Chopra, O.K.

    1993-12-01

    Tests were conducted on the compatibility of gallium with candidate structural materials for the International Thermonuclear Experimental Reactor, e.g., Type 316 SS, Inconel 625, and Nb-5 Mo-1 Zr alloy, as well as Armco iron, Nickel 270, and pure chromium. Type 316 stainless steel is least resistant to corrosion in static gallium and Nb-5 Mo-1 Zr alloy is most resistant. At 400{degrees}C, corrosion rates are {approx}4.0, 0.5, and 0.03 mm/yr for type 316 SS, Inconel 625, and Nb-5 Mo- 1 Zr alloy, respectively. The pure metals react rapidly with gallium. In contrast to findings in earlier studies, pure iron shows greater corrosion than nickel. The corrosion rates at 400{degrees}C are {ge}88 and 18 mm/yr, respectively, for Armco iron and Nickel 270. The results indicate that at temperatures up to 400{degrees}C, corrosion occurs primarily by dissolution and is accompanied by formation of metal/gallium intermetallic compounds. The solubility data for pure metals and oxygen in gallium are reviewed. The physical, chemical, and radioactive properties of gallium are also presented. The supply and availability of gallium, as well as price predictions through the year 2020, are summarized.

  2. Fracture toughness of irradiated candidate materials for ITER first wall/blanket structures: Summary report

    Energy Technology Data Exchange (ETDEWEB)

    Alexander, D.J.; Pawel, J.E.; Grossbeck, M.L.; Rowcliffe, A.F. [Oak Ridge National Lab., TN (United States)] [and others

    1996-04-01

    Disk compact specimens of candidate materials for first wall/blanket structures in ITER have been irradiated to damage levels of about 3 dpa at nominal irradiation temperatures of either 90 250{degrees}C. These specimens have been tested over a temperature range from 20 to 250{degrees}C to determine J-integral values and tearing moduli. The results show that irradiation at these temperatures reduces the fracture toughness of austenic stainless steels, but the toughness remains quite high. The toughness decreases as the temperature increases. Irradiation at 250{degrees}C is more damaging that at 90{degrees}C, causing larger decreases in the fracture toughness. The ferritic-martensitic steels HT-9 and F82H show significantly greater reductions in fracture toughness that the austenitic stainless steels.

  3. Neutron irradiation behavior of ITER candidate beryllium grades

    Energy Technology Data Exchange (ETDEWEB)

    Kupriyanov, I.B.; Gorokhov, V.A.; Nikolaev, G.N. [A.A.Bochvar All-Russia Scientific Research Inst. of Inorganic Materials (VNIINM), Moscow (Russian Federation); Melder, R.R.; Ostrovsky, Z.E.

    1998-01-01

    Beryllium is one of the main candidate materials both for the neutron multiplier in a solid breeding blanket and for the plasma facing components. That is why its behaviour under the typical for fusion reactor loading, in particular, under the neutron irradiation is of a great importance. This paper presents mechanical properties, swelling and microstructure of six beryllium grades (DshG-200, TR-30, TshG-56, TRR, TE-30, TIP-30) fabricated by VNIINM, Russia and also one - (S-65) fabricated by Brush Wellman, USA. The average grain size of the beryllium grades varied from 8 to 25 {mu}m, beryllium oxide content was 0.8-3.2 wt. %, initial tensile strength was 250-680 MPa. All the samples were irradiated in active zone of SM-3 reactor up to the fast neutron fluence (5.5-6.2) {center_dot} 10{sup 21} cm{sup -2} (2.7-3.0 dpa, helium content up to 1150 appm), E > 0.1 MeV at two temperature ranges: T{sub 1} = 130-180degC and T{sub 2} = 650-700degC. After irradiation at 130-180degC no changes in samples dimensions were revealed. After irradiation at 650-700degC swelling of the materials was found to be in the range 0.1-2.1 %. Beryllium grades TR-30 and TRR, having the smallest grain size and highest beryllium oxide content, demonstrated minimal swelling, which was no more than 0.1 % at 650-700degC and fluence 5.5 {center_dot} 10{sup 21} cm{sup -2}. Tensile and compression test results and microstructure parameters measured before and after irradiation are also presented. (author)

  4. Development of structural design criteria for ITER.

    Energy Technology Data Exchange (ETDEWEB)

    Majumdar, S.

    1998-06-22

    The irradiation environment experienced by the in-vessel components of fusion reactors such as HER presents structural design challenges not envisioned in the development of existing structural design criteria such as the ASME Code or RCC-MR. From the standpoint of design criteria, the most significant issues stem from the irradiation-induced changes in material properties, specifically the reduction of ductility, strain hardening capability, and fracture toughness with neutron irradiation. Recently, Draft 7 of the interim ITER structural design criteria (ISDC), which provide new rules for guarding against such problems, was released for trial use by the ITER designers. The new rules, which were derived from a simple model based on the concept of elastic follow up factor, provide primary and secondary stress limits as functions of uniform elongation and ductility. The implication of these rules on the allowable surface heat flux on typical first walls made of type 316 stainless steel and vanadium alloys are discussed.

  5. Iter

    Science.gov (United States)

    Iotti, Robert

    2015-04-01

    ITER is an international experimental facility being built by seven Parties to demonstrate the long term potential of fusion energy. The ITER Joint Implementation Agreement (JIA) defines the structure and governance model of such cooperation. There are a number of necessary conditions for such international projects to be successful: a complete design, strong systems engineering working with an agreed set of requirements, an experienced organization with systems and plans in place to manage the project, a cost estimate backed by industry, and someone in charge. Unfortunately for ITER many of these conditions were not present. The paper discusses the priorities in the JIA which led to setting up the project with a Central Integrating Organization (IO) in Cadarache, France as the ITER HQ, and seven Domestic Agencies (DAs) located in the countries of the Parties, responsible for delivering 90%+ of the project hardware as Contributions-in-Kind and also financial contributions to the IO, as ``Contributions-in-Cash.'' Theoretically the Director General (DG) is responsible for everything. In practice the DG does not have the power to control the work of the DAs, and there is not an effective management structure enabling the IO and the DAs to arbitrate disputes, so the project is not really managed, but is a loose collaboration of competing interests. Any DA can effectively block a decision reached by the DG. Inefficiencies in completing design while setting up a competent organization from scratch contributed to the delays and cost increases during the initial few years. So did the fact that the original estimate was not developed from industry input. Unforeseen inflation and market demand on certain commodities/materials further exacerbated the cost increases. Since then, improvements are debatable. Does this mean that the governance model of ITER is a wrong model for international scientific cooperation? I do not believe so. Had the necessary conditions for success

  6. Structural analysis of the ITER Vacuum Vessel regarding 2012 ITER Project-Level Loads

    Energy Technology Data Exchange (ETDEWEB)

    Martinez, J.-M., E-mail: jean-marc.martinez@live.fr [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul lez Durance (France); Jun, C.H.; Portafaix, C.; Choi, C.-H.; Ioki, K.; Sannazzaro, G.; Sborchia, C. [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul lez Durance (France); Cambazar, M.; Corti, Ph.; Pinori, K.; Sfarni, S.; Tailhardat, O. [Assystem EOS, 117 rue Jacquard, L' Atrium, 84120 Pertuis (France); Borrelly, S. [Sogeti High Tech, RE2, 180 rue René Descartes, Le Millenium – Bat C, 13857 Aix en Provence (France); Albin, V.; Pelletier, N. [SOM Calcul – Groupe ORTEC, 121 ancien Chemin de Cassis – Immeuble Grand Pré, 13009 Marseille (France)

    2014-10-15

    Highlights: • ITER Vacuum Vessel is a part of the first barrier to confine the plasma. • ITER Vacuum Vessel as Nuclear Pressure Equipment (NPE) necessitates a third party organization authorized by the French nuclear regulator to assure design, fabrication, conformance testing and quality assurance, i.e. Agreed Notified Body (ANB). • A revision of the ITER Project-Level Load Specification was implemented in April 2012. • ITER Vacuum Vessel Loads (seismic, pressure, thermal and electromagnetic loads) were summarized. • ITER Vacuum Vessel Structural Margins with regards to RCC-MR code were summarized. - Abstract: A revision of the ITER Project-Level Load Specification (to be used for all systems of the ITER machine) was implemented in April 2012. This revision supports ITER's licensing by accommodating requests from the French regulator to maintain consistency with the plasma physics database and our present understanding of plasma transients and electro-magnetic (EM) loads, to investigate the possibility of removing unnecessary conservatism in the load requirements and to review the list and definition of incidental cases. The purpose of this paper is to present the impact of this 2012 revision of the ITER Project-Level Load Specification (LS) on the ITER Vacuum Vessel (VV) loads and the main structural margins required by the applicable French code, RCC-MR.

  7. Irradiation tests of ITER candidate Hall sensors using two types of neutron spectra.

    Science.gov (United States)

    Ďuran, I; Bolshakova, I; Viererbl, L; Sentkerestiová, J; Holyaka, R; Lahodová, Z; Bém, P

    2010-10-01

    We report on irradiation tests of InSb based Hall sensors at two irradiation facilities with two distinct types of neutron spectra. One was a fission reactor neutron spectrum with a significant presence of thermal neutrons, while another one was purely fast neutron field. Total neutron fluence of the order of 10(16) cm(-2) was accumulated in both cases, leading to significant drop of Hall sensor sensitivity in case of fission reactor spectrum, while stable performance was observed at purely fast neutron spectrum. This finding suggests that performance of this particular type of Hall sensors is governed dominantly by transmutation. Additionally, it further stresses the need to test ITER candidate Hall sensors under neutron flux with ITER relevant spectrum.

  8. The ITER EC H&CD upper launcher: Structural design

    NARCIS (Netherlands)

    Spaeh, P.; Aiello, G.; de M. Baar,; Chavan, R.; Elzendoorn, B.; Goodman, T.; Henderson, M.; Kleefeldt, K.; Landis, J. D.; Meier, A.; Ronden, D.; Saibene, G.; Scherer, T.; Schreck, S.; Serikov, A.; Strauss, D.; Vaccaro, A.

    2011-01-01

    Four ITER EC H&CD (Electron Cyclotron Heating and Current Drive) Upper Launchers will be installed in the ITER Tokamak to counteract plasma instabilities by injection of up to 20 MW of millimeter-wave power at 170 GHz. Each Launcher features a structural system which is equipped with eight b

  9. Development and benchmarking of TASSER(iter) for the iterative improvement of protein structure predictions.

    Science.gov (United States)

    Lee, Seung Yup; Skolnick, Jeffrey

    2007-07-01

    To improve the accuracy of TASSER models especially in the limit where threading provided template alignments are of poor quality, we have developed the TASSER(iter) algorithm which uses the templates and contact restraints from TASSER generated models for iterative structure refinement. We apply TASSER(iter) to a large benchmark set of 2,773 nonhomologous single domain proteins that are iter) models have a smaller global average RMSD of 5.48 A compared to 5.81 A RMSD of the original TASSER models. Classifying the targets by the level of prediction difficulty (where Easy targets have a good template with a corresponding good threading alignment, Medium targets have a good template but a poor alignment, and Hard targets have an incorrectly identified template), TASSER(iter) (TASSER) models have an average RMSD of 4.15 A (4.35 A) for the Easy set and 9.05 A (9.52 A) for the Hard set. The largest reduction of average RMSD is for the Medium set where the TASSER(iter) models have an average global RMSD of 5.67 A compared to 6.72 A of the TASSER models. Seventy percent of the Medium set TASSER(iter) models have a smaller RMSD than the TASSER models, while 63% of the Easy and 60% of the Hard TASSER models are improved by TASSER(iter). For the foldable cases, where the targets have a RMSD to the native iter) shows obvious improvement over TASSER models: For the Medium set, it improves the success rate from 57.0 to 67.2%, followed by the Hard targets where the success rate improves from 32.0 to 34.8%, with the smallest improvement in the Easy targets from 82.6 to 84.0%. These results suggest that TASSER(iter) can provide more reliable predictions for targets of Medium difficulty, a range that had resisted improvement in the quality of protein structure predictions.

  10. Automatic Control of ITER-like Structures

    Energy Technology Data Exchange (ETDEWEB)

    Bosia, G.; Bremond, S

    2005-07-01

    In ITER Ion Cyclotron System requires a power transfer efficiency in excess of 90% from power source to plasma in quasi continuous operation. This implies the availability of a control system capable of optimizing the array radiation spectrum, automatically acquiring impedance match between the power source and the plasma loaded array at the beginning of the power pulse and maintaining it against load variations due to plasma position and plasma edge parameters fluctuations, rapidly detecting voltage breakdowns in the array and/or in the transmission system and reliably discriminating them from fast load variations. In this paper a proposal for a practical ITER control system, including power, phase, frequency and impedance matching is described. (authors)

  11. ITER vacuum vessel structural analysis completion during manufacturing phase

    Energy Technology Data Exchange (ETDEWEB)

    Martinez, J.-M., E-mail: jean-marc.martinez@live.fr [ITER Organization, Route Vinon sur Verdon, CS 90046, 13067, St. Paul lez Durance, Cedex (France); Alekseev, A.; Sborchia, C.; Choi, C.H.; Utin, Y.; Jun, C.H.; Terasawa, A.; Popova, E.; Xiang, B.; Sannazaro, G.; Lee, A.; Martin, A.; Teissier, P.; Sabourin, F. [ITER Organization, Route Vinon sur Verdon, CS 90046, 13067, St. Paul lez Durance, Cedex (France); Caixas, J.; Fernandez, E.; Zarzalejos, J.M. [F4E, c/Josep Pla, n.2, Torres Diagonal Litoral, Edificio B3, E-08019, Barcelona (Spain); Kim, H.-S.; Kim, Y.G. [ITER Korea, National Fusion Research Institute, Daejeon (Korea, Republic of); Privalova, E. [NTC “Sintez”, Efremov Inst., 189631 Metallostroy, St. Petersburg (Russian Federation); and others

    2016-11-01

    Highlights: • ITER Vacuum Vessel (VV) is a part of the first barrier to confine the plasma. • A Nuclear Pressure Equipment necessitates Agreed Notified Body to assure design, fabrication, and conformance testing and quality assurance. • Some supplementary RCC-MR margin targets have been considered to guarantee considerable structural margins in areas not inspected in operation. • Many manufacturing deviation requests (MDR) and project change requests (PCR) impose to re-evaluate the structural margin. • Several structural analyses were performed with global and local models to guarantee the structural integrity of the whole ITER Vacuum Vessel. - Abstract: Some years ago, analyses were performed by ITER Organization Central Team (IO-CT) to verify the structural integrity of the ITER vacuum vessel baseline design fixed in 2010 and classified as a Protection Important Component (PIC). The manufacturing phase leads the ITER Organization domestic agencies (IO-DA) and their contracted manufacturers to propose detailed design improvements to optimize the manufacturing or inspection process. These design and quality inspection changes can affect the structural margins with regards to the Codes&Standards and thus oblige to evaluate one more time the modified areas. This paper proposes an overview of the additional analyses already performed to guarantee the structural integrity of the manufacturing designs. In this way, CT and DAs have been strongly involved to keep the considerable margins obtained previously which were used to fix reasonable compensatory measures for the lack of In Service Inspections of a Nuclear Pressure Equipment (NPE).

  12. Real-time feedback from iterative electronic structure calculations

    CERN Document Server

    Vaucher, Alain C; Reiher, Markus

    2015-01-01

    Real-time feedback from iterative electronic structure calculations requires to mediate between the inherently unpredictable execution times of the iterative algorithm employed and the necessity to provide data in fixed and short time intervals for real-time rendering. We introduce the concept of a mediator as a component able to deal with infrequent and unpredictable reference data to generate reliable feedback. In the context of real-time quantum chemistry, the mediator takes the form of a surrogate potential that has the same local shape as the first-principles potential and can be evaluated efficiently to deliver atomic forces as real-time feedback. The surrogate potential is updated continuously by electronic structure calculations and guarantees to provide a reliable response to the operator for any molecular structure. To demonstrate the application of iterative electronic structure methods in real-time reactivity exploration, we implement self-consistent semi-empirical methods as the data source and a...

  13. Structural analysis of ITER multi-purpose deployer

    Energy Technology Data Exchange (ETDEWEB)

    Manuelraj, Manoah Stephen, E-mail: manoah@ipr.res.in [Institute for Plasma Research, Gandhinagar, Gujarat 382428 (India); Dutta, Pramit; Gotewal, Krishan Kumar; Rastogi, Naveen [Institute for Plasma Research, Gandhinagar, Gujarat 382428 (India); Tesini, Alessandro [ITER Organization, Route de Vinon-sur-Verdon, CS 90046, 1306 St Paul lez Durance Cedex (France); Choi, Chang-Hwan, E-mail: chang-hwan.choi@iter.org [ITER Organization, Route de Vinon-sur-Verdon, CS 90046, 1306 St Paul lez Durance Cedex (France)

    2016-11-01

    Highlights: • System modelling for structural analysis of the Multi-Purpose Deployer (MPD). • Finite element modeling of the Multi-Purpose Deployer (MPD). • Static, modal and seismic response analysis of the Multi-Purpose Deployer (MPD). • Iterative structural analysis and design update to satisfy the structural criteria. • Modal analysis for various kinematic configurations. • Reaction force calculations on the interfacing systems. - Abstract: The Multi-Purpose Deployer (MPD) is a general purpose ITER in-vessel remote handling (RH) system. The main handling equipment, known as the MPD Transporter, consists of a series of linked bodies, which provide anchoring to the vacuum vessel port and an articulated multi-degree of freedom motion to perform various in-vessel maintenance tasks. During the in-vessel operations, the structural integrity of the system should be guaranteed against various operational and seismic loads. This paper presents the structural analysis results of the concept design of the MPD Transporter considering the seismic events. Static structural, modal and frequency response spectrum analyses have been performed to verify the structural integrity of the system, and to provide reaction forces to the interfacing systems such as vacuum vessel and cask. Iterative analyses and design updates are carried out based on the reference design of the system to improve the structural behavior of the system. The frequency responses of the system in various kinematics and payloads are assessed.

  14. Real-time feedback from iterative electronic structure calculations.

    Science.gov (United States)

    Vaucher, Alain C; Haag, Moritz P; Reiher, Markus

    2016-04-05

    Real-time feedback from iterative electronic structure calculations requires to mediate between the inherently unpredictable execution times of the iterative algorithm used and the necessity to provide data in fixed and short time intervals for real-time rendering. We introduce the concept of a mediator as a component able to deal with infrequent and unpredictable reference data to generate reliable feedback. In the context of real-time quantum chemistry, the mediator takes the form of a surrogate potential that has the same local shape as the first-principles potential and can be evaluated efficiently to deliver atomic forces as real-time feedback. The surrogate potential is updated continuously by electronic structure calculations and guarantees to provide a reliable response to the operator for any molecular structure. To demonstrate the application of iterative electronic structure methods in real-time reactivity exploration, we implement self-consistent semiempirical methods as the data source and apply the surrogate-potential mediator to deliver reliable real-time feedback.

  15. Iterating skeletons

    DEFF Research Database (Denmark)

    Dieterle, Mischa; Horstmeyer, Thomas; Berthold, Jost;

    2012-01-01

    block inside a bigger structure. In this work, we present a general framework for skeleton iteration and discuss requirements and variations of iteration control and iteration body. Skeleton iteration is expressed by synchronising a parallel iteration body skeleton with a (likewise parallel) state...

  16. Influence of reactor irradiation on the mechanical behavior of ITER TF coil candidate insulation systems

    Energy Technology Data Exchange (ETDEWEB)

    Bittner-Rohrhofer, K. E-mail: kbittner@ati.ac.at; Humer, K.; Fillunger, H.; Maix, R.K.; Wang, Z.D.; Weber, H.W

    2003-09-01

    Extensive material tests have to be performed in order to obtain information on the radiation induced change in the mechanical behavior of insulating materials for the ITER Toroidal Field (TF) coil. The investigated insulation systems are R-glass fiber reinforced tapes, vacuum impregnated with a DGEBA epoxy resin and interleafed with Kapton H-foils. According to the actual operating conditions of ITER-FEAT, the systems were irradiated in the TRIGA reactor (Vienna, Austria) to neutron fluences of 5x10{sup 21} and 1x10{sup 22} m{sup -2} (E>0.1 MeV). Static tensile, short-beam-shear (SBS) as well as double-lap-shear (DLS) tests were carried out at 77 K prior to and after irradiation. Furthermore, results on swelling and weight loss as well as on the material properties under tension-tension fatigue loading conditions are presented.

  17. Piping structural design for the ITER thermal shield manifold

    Energy Technology Data Exchange (ETDEWEB)

    Noh, Chang Hyun, E-mail: chnoh@nfri.re.kr [ITER Korea, National Fusion Research Institute, Daejeon 305-333 (Korea, Republic of); Chung, Wooho, E-mail: whchung@nfri.re.kr [ITER Korea, National Fusion Research Institute, Daejeon 305-333 (Korea, Republic of); Nam, Kwanwoo; Kang, Kyoung-O. [ITER Korea, National Fusion Research Institute, Daejeon 305-333 (Korea, Republic of); Bae, Jing Do; Cha, Jong Kook [Korea Marine Equipment Research Institute, Busan 606-806 (Korea, Republic of); Kim, Kyoung-Kyu [Mecha T& S, Jinju-si 660-843 (Korea, Republic of); Hamlyn-Harris, Craig; Hicks, Robby; Her, Namil; Jun, Chang-Hoon [ITER Organization, Route de Vinon-sur-Verdon, CS 90 046, 13067 St. Paul Lez Durance Cedex (France)

    2015-10-15

    Highlights: • We finalized piping design of ITER thermal shield manifold for procurement. • Support span is determined by stress and deflection limitation. • SQP, which is design optimization method, is used for the pipe design. • Benchmark analysis is performed to verify the analysis software. • Pipe design is verified by structural analyses. - Abstract: The thermal shield (TS) provides the thermal barrier in the ITER tokamak to minimize heat load transferred by thermal radiation from the hot components to the superconducting magnets operating at 4.2 K. The TS is actively cooled by 80 K pressurized helium gas which flows from the cold valve box to the cooling tubes on the TS panels via manifold piping. This paper describes the manifold piping design and analysis for the ITER thermal shield. First, maximum allowable span for the manifold support is calculated based on the simple beam theory. In order to accommodate the thermal contraction in the manifold feeder, a contraction loop is designed and applied. Sequential Quadratic Programming (SQP) method is used to determine the optimized dimensions of the contraction loop to ensure adequate flexibility of manifold pipe. Global structural behavior of the manifold is investigated when the thermal movement of the redundant (un-cooled) pipe is large.

  18. Structural finite element analysis of ITER In-wall shield

    Energy Technology Data Exchange (ETDEWEB)

    Shaikh, Moinuddin S., E-mail: moins@iter-india.org [ITER-India, Institute for Plasma Research, A-29, GIDC Electronic Estate, Sector 25, Gandhinagar 382016 (India); Pathak, H.A. [ITER-India, Institute for Plasma Research, A-29, GIDC Electronic Estate, Sector 25, Gandhinagar 382016 (India); Oliver, Tailhardat [Assystem EOS, Zac Saint Martin, 23 Rue Benjamin Franklin, 84120 Pertuis (France); Wang, Xiaoyu [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France)

    2013-10-15

    The In-wall shielding (IWS) located between two shells of the vacuum vessel is part of the vacuum vessel of ITER. The function of the IWS is to provide neutron shielding and to reduce toroidal field ripple. The IWS plates are fastened using M30 bolts to hold them securely and the IWS blocks are mounted to the support ribs using the brackets and M20 bolts. The paper presents a structural finite element analysis of one sample IWS block carried out using ANSYS* to establish the benchmark analysis procedure of the IWS blocks. Boundary conditions are set taking into account the assembly procedure of the IWS blocks. The analysis is carried out in three load steps (1). Pretension on M30 (2). Pretension on M30 and M20 and (3) pretension on M30 and M20 plus Electromagnetic forces, dynamic forces, Seismic forces, etc. The stresses and displacements of individual IWS components are evaluated against their allowable stress limits as per an ASME guideline. The ITER-India’s results of analysis are compared with the ITER-IO’s results for the worst category 3-load step 3 and they are found comparable. This establishes the analysis procedure to be used for all of the IWS blocks.

  19. Structural optimization for a jaw using iterative Kriging metamodels

    Energy Technology Data Exchange (ETDEWEB)

    Bang, Il Kwon; Han, Dong Seop; Han, Geun Jo; Lee, Kwon Hee [Dong-A University, Busan (Korea, Republic of)

    2008-09-15

    Rail clamps are mechanical components installed to fix the container crane to its lower members against wind blast or slip. Rail clamps should be designed to survive harsh wind loading conditions. In this study, a jaw structure, which is a part of a wedge-typed rail clamp, is optimized with respect to its strength under a severe wind loading condition. According to the classification of structural optimization, the structural optimization of a jaw is included in the category of shape optimization. Conventional structural optimization methods have difficulties in defining complex shape design variables and preventing mesh distortions. To overcome the difficulties, a metamodel using the Kriging interpolation method is introduced to replace the true response by an approximate one. This research presents the shape optimization of a jaw using iterative Kriging interpolation models and a simulated annealing algorithm. The new Kriging models are iteratively constructed by refining the former Kriging models. This process is continued until the convergence criteria are satisfied. The optimum results obtained by the suggested method are compared with those obtained by the DOE (design of experiments) and VT (variation technology) methods built in ANSYS WORKBENCH

  20. Structural Analysis of the ITER VV Lower Port Region

    Institute of Scientific and Technical Information of China (English)

    CAI Yingxiang; WU Songtao; YU Jie

    2007-01-01

    A structural analysis of the International Thermonuclear Experimental Reactor (ITER)vacuum vessel's lower port region Was presented by means of a finite element analysis method.The purpose is to evaluate the stress and displacement level on this structure under various combinations of five designed loads,including the gravity of the vacuum vessel,seismic loads,electromagnetic loads,and possible pressure loads to ensure structural safety.The cyclic symmetry finite element model of this structure Was developed by using ANSYS code.The results showed that the maximum stress does not exceed the allowable value for any of the load combinations according to ASME code and the nine vacuum vessel(VV)supports have the ability to sustain the entire VV and in vessel-components and withstand load combinations under both normal as well as off-normal operation conditions.Stress mainly concentrates on the connecting region of the VV support and lower port stub extension.

  1. Numerical Analysis on Neutron Shielding Structure of ITER Vacuum Vessel

    Institute of Scientific and Technical Information of China (English)

    LIU Changle; WU Songtao; YU Jie; SHENG Daolin

    2008-01-01

    The neutron shielding component of ITER (International Thermonuclear Experi-mental Reactor) vacuum vessel is a kind of structure resembling a wall in appearance. A FE (finite element) model is set up by using ANSYS code in terms of its structural features. Static analysis, thermal expansion analysis and dynamic analysis are performed. The static results show that the stress and displacement distribution are allowable, but the high stress appears in the junction between the upper and lower parts. The modal analysis indicates that the biggest defor-mation exists in the port area. Through modal superposition, the single-point response has been found with the lower rank frequency of the acceleration seismic response spectrum. But the defor-mation and the stress values are within the permissible limit. The analysis results would benefit the work in the next step and provide some reference for the implementation of the engineering plan in the future.

  2. The ITER EC H and CD upper launcher: Structural system

    Energy Technology Data Exchange (ETDEWEB)

    Spaeh, Peter, E-mail: peter.spaeh@kit.edu [Karlsruhe Institute of Technology, Institute for Applied Materials, Association KIT-EURATOM, P.O. Box 3640, D-76021 Karlsruhe (Germany); Aiello, Gaetano; Gessner, Robby; Grossetti, Giovanni; Meier, Andreas; Scherer, Theo; Schreck, Sabine [Karlsruhe Institute of Technology, Institute for Applied Materials, Association KIT-EURATOM, P.O. Box 3640, D-76021 Karlsruhe (Germany); Serikov, Arkady [Karlsruhe Institute of Technology, Institute for Neutron Physics and Reactor Technology, Association KIT-EURATOM, P.O. Box 3640, D-76021 Karlsruhe (Germany); Strauss, Dirk; Vaccaro, Alessandro [Karlsruhe Institute of Technology, Institute for Applied Materials, Association KIT-EURATOM, P.O. Box 3640, D-76021 Karlsruhe (Germany); Weinhorst, Bastian [Karlsruhe Institute of Technology, Institute for Neutron Physics and Reactor Technology, Association KIT-EURATOM, P.O. Box 3640, D-76021 Karlsruhe (Germany)

    2013-10-15

    Highlights: ► ITER EC H and CD Launcher goes towards final design. ► European consortium founded for bringing the EC H and CD launcher towards final design. ► New design updates for dedicated components of the ITER EC H and CD launcher. -- Abstract: After approval of the preliminary design of the ITER EC H and CD Upper Launcher, ECHUL-CA, a consortium of several European research institutes, was founded to pool resources for approaching the final design. At the end of 2011 the consortium has signed a 2 years contract with F4E to go ahead with the work on the launcher. The contract deals with design work on both the port plug, forming the structural system, and the mm-wave-system, which injects the RF-power into the plasma. Within the period of this contract all components being part of the Tritium confinement, of which the closure plate, the support flange, the diamond windows and the waveguide feed-throughs are the most outstanding ones, will get the status of the final design. Important steps to be done for the structural system are the optimization of the mechanical behavior of the launcher, leading to minimum deflections of the port plug during plasma disruptions and optimum seismic resistance. To reduce the effect of halo currents it was decided to recess the first wall of 100 mm compared to the regular blanket tangent. This recess requires substantial changes of the cooling system and the thermo-hydraulic design of the launcher. Also the layout of the shielding arrangement and the integration of the mm-wave system need significant revision. Moreover manufacturing aspects and enhanced remote handling capability are taken into account. For the final design also quality aspects must be considered; thus the design is elaborated with respect to applicable codes and standards, material specifications, risk analyses and the RAMI (reliability, availability, maintainability and inspectability) analysis to guarantee maximum performance of the device. This paper

  3. Protein-complex structure completion using IPCAS (Iterative Protein Crystal structure Automatic Solution).

    Science.gov (United States)

    Zhang, Weizhe; Zhang, Hongmin; Zhang, Tao; Fan, Haifu; Hao, Quan

    2015-07-01

    Protein complexes are essential components in many cellular processes. In this study, a procedure to determine the protein-complex structure from a partial molecular-replacement (MR) solution is demonstrated using a direct-method-aided dual-space iterative phasing and model-building program suite, IPCAS (Iterative Protein Crystal structure Automatic Solution). The IPCAS iteration procedure involves (i) real-space model building and refinement, (ii) direct-method-aided reciprocal-space phase refinement and (iii) phase improvement through density modification. The procedure has been tested with four protein complexes, including two previously unknown structures. It was possible to use IPCAS to build the whole complex structure from one or less than one subunit once the molecular-replacement method was able to give a partial solution. In the most challenging case, IPCAS was able to extend to the full length starting from less than 30% of the complex structure, while conventional model-building procedures were unsuccessful.

  4. The Structural Design and Analysis of Pallet in ITER Transfer Cask for Remote Handling Operations

    Science.gov (United States)

    Zhou, Zibo; Yao, Damao; Cao, Lei; Li, Ge

    2009-06-01

    Necessary adjustment ranges and accuracies of the pallet for ITER are presented. Detailed structural designs and structural finite element analyses for pallet components are made to determine whether the results satisfy the requirements of the pallet structure to be used in ITER.

  5. The Structural Design and Analysis of Pallet in ITER Transfer Cask for Remote Handling Operations

    Institute of Scientific and Technical Information of China (English)

    ZHOU Zibo; YAO Damao; CAO Lei; LI Ge

    2009-01-01

    Necessary adjustment ranges and accuracies of the pallet for ITER are presented. Detailed structural designs and structural finite element analyses for pallet components are made to determine whether the results satisfy the requirements of the pallet structure to be used in ITER.

  6. Automatic Detection and Quantification of WBCs and RBCs Using Iterative Structured Circle Detection Algorithm

    Directory of Open Access Journals (Sweden)

    Yazan M. Alomari

    2014-01-01

    Full Text Available Segmentation and counting of blood cells are considered as an important step that helps to extract features to diagnose some specific diseases like malaria or leukemia. The manual counting of white blood cells (WBCs and red blood cells (RBCs in microscopic images is an extremely tedious, time consuming, and inaccurate process. Automatic analysis will allow hematologist experts to perform faster and more accurately. The proposed method uses an iterative structured circle detection algorithm for the segmentation and counting of WBCs and RBCs. The separation of WBCs from RBCs was achieved by thresholding, and specific preprocessing steps were developed for each cell type. Counting was performed for each image using the proposed method based on modified circle detection, which automatically counted the cells. Several modifications were made to the basic (RCD algorithm to solve the initialization problem, detecting irregular circles (cells, selecting the optimal circle from the candidate circles, determining the number of iterations in a fully dynamic way to enhance algorithm detection, and running time. The validation method used to determine segmentation accuracy was a quantitative analysis that included Precision, Recall, and F-measurement tests. The average accuracy of the proposed method was 95.3% for RBCs and 98.4% for WBCs.

  7. Structural materials for ITER in-vessel component design

    Science.gov (United States)

    Kalinin, G.; Gauster, W.; Matera, R.; Tavassoli, A.-A. F.; Rowcliffe, A.; Fabritsiev, S.; Kawamura, H.

    1996-10-01

    The materials proposed for ITER in-vessel components have to exhibit adequate performance for the operating lifetime of the reactor or for specified replacement intervals. Estimates show that maximum irradiation dose to be up to 5-7 dpa (for 1 MWa/m 2 in the basic performance phase (BPP)) within a temperature range from 20 to 300°C. Austenitic SS 316LN-ITER Grade was defined as a reference option for the vacuum vessel, blanket, primary wall, pipe lines and divertor body. Conventional technologies and mill products are proposed for blanket, back plate and manifold manufacturing. HIPing is proposed as a reference manufacturing method for the primary wall and blanket and as an option for the divertor body. The existing data show that mechanical properties of HIPed SS are no worse than those of forged 316LN SS. Irradiation will result in property changes. Minimum ductility has been observed after irradiation in an approximate temperature range between 250 and 350°C, for doses of 5-10 dpa. In spite of radiation-induced changes in tensile deformation behavior, the fracture remains ductile. Irradiation assisted corrosion cracking is a concern for high doses of irradiation and at high temperatures. Re-welding is one of the critical issues because of the need to replace failed components. It is also being considered for the replacement of shielding blanket modules by breeding modules after the BPP. Estimates of radiation damage at the locations for re-welding show that the dose will not exceed 0.05 dpa (with He generation of 1 appm) for the manifold and 0.01 dpa (with He generation 0.1 appm) for the back plate for the BPP of ITER operation. Existing experimental data show that these levels will not result in property changes for SS; however, neutron irradiation and He generation promote crack formation in the heat affected zone during welding. Cu based alloys, DS-Cu (Glidcop A125) and PHCu CuCrZr bronze) are proposed as a structural materials for high heat flux

  8. Iterating skeletons

    DEFF Research Database (Denmark)

    Dieterle, Mischa; Horstmeyer, Thomas; Berthold, Jost;

    2012-01-01

    Skeleton-based programming is an area of increasing relevance with upcoming highly parallel hardware, since it substantially facilitates parallel programming and separates concerns. When parallel algorithms expressed by skeletons involve iterations – applying the same algorithm repeatedly...... block inside a bigger structure. In this work, we present a general framework for skeleton iteration and discuss requirements and variations of iteration control and iteration body. Skeleton iteration is expressed by synchronising a parallel iteration body skeleton with a (likewise parallel) state......-based iteration control, where both skeletons offer supportive type safety by dedicated types geared towards stream communication for the iteration. The skeleton iteration framework is implemented in the parallel Haskell dialect Eden. We use example applications to assess performance and overhead....

  9. Optimization of tungsten castellated structures for the ITER divertor

    Science.gov (United States)

    Litnovsky, A.; Hellwig, M.; Matveev, D.; Komm, M.; van den Berg, M.; De Temmerman, G.; Rudakov, D.; Ding, F.; Luo, G.-N.; Krieger, K.; Sugiyama, K.; Pitts, R. A.; Petersson, P.

    2015-08-01

    In ITER, the plasma-facing components (PFCs) of the first wall and the divertor armor will be castellated to improve their thermo-mechanical stability and to limit forces due to induced currents. The fuel accumulation in the gaps may significantly contribute to the in-vessel fuel inventory. Castellation shaping may be the most straightforward way to minimize the fuel inventory and to alleviate the thermal loads onto castellations. A new castellation shape was proposed and comparative modeling of conventional (rectangular) and shaped castellation was performed for ITER conditions. Shaped castellation was predicted to be capable to operate under stationary heat load of 20 MW/m2. An 11-fold decrease of beryllium (Be) content in the gaps of the shaped cells alone with a 7-fold decrease of carbon content was predicted. In order to validate the predictive capabilities of modeling tools used for ITER conditions, the dedicated modeling with the same codes was made for existing tokamaks and benchmarked with the results of multi-machine experiments. For the castellations exposed in TEXTOR and DIII-D, the carbon amount in the gaps of shaped cells was 1.9-2.3 times smaller than that of rectangular ones. Modeling for TEXTOR conditions yielded to 1.5-fold decrease of carbon content in the gaps of shaped castellation outlining fair agreement with the experiment. At the same time, a number of processes, like enhanced erosion of molten layer yet need to be implemented in the codes in order to increase the accuracy of predictions for ITER.

  10. Network Structures between Strategies in Iterated Prisoners' Dilemma Games

    CERN Document Server

    Kim, Young Jin; Son, Seung-Woo

    2014-01-01

    We use replicator dynamics to study an iterated prisoners' dilemma game with memory. In this study, we investigate the characteristics of all 32 possible strategies with a single-step memory by observing the results when each strategy encounters another one. Based on these results, we define similarity measures between the 32 strategies and perform a network analysis of the relationship between the strategies by constructing a strategies network. Interestingly, we find that a win-lose circulation, like rock-paper-scissors, exists between strategies and that the circulation results from one unusual strategy.

  11. Rapid iterative method for electronic-structure eigenproblems using localised basis functions

    Science.gov (United States)

    Rayson, M. J.; Briddon, P. R.

    2008-01-01

    Eigenproblems resulting from the use of localised basis functions (typically Gaussian or Slater type orbitals) in density functional electronic-structure calculations are often solved using direct linear algebra. A full implementation is presented built around an iterative method known as 'residual minimisation—direct inversion of the iterative subspace' (RM-DIIS) to be used to solve many similar eigenproblems in a self-consistency cycle. The method is more efficient than direct methods and exhibits superior scaling on parallel supercomputers.

  12. Final design of the generic upper port plug structure for ITER diagnostic systems

    NARCIS (Netherlands)

    Pak, S.; Feder, R.; Giacomin, T.; Guirao, J.; Iglesias, S.; Josseaume, F.; Kalish, M.; Loesser, D.; Maquet, P.; Ronden, D.; Ordieres, J.; Panizo, M.; Pitcher, S.; M. Portalès,; Proust, M.; Serikov, A.; Suarez, A.; Tanchuk, V.; Udintsev, V.; Vacas, C.; Walsh, M.; Zhai, Y.

    2016-01-01

    The generic upper port plug (GUPP) structure in ITER is a 6 m long metal box which deploys diagnostic components into the vacuum vessel. This structure is commonly used for all the diagnostic upper ports. The final design of the GUPP structure, which has successfully passed the final design review i

  13. Robust Mean and Covariance Structure Analysis through Iteratively Reweighted Least Squares.

    Science.gov (United States)

    Yuan, Ke-Hai; Bentler, Peter M.

    2000-01-01

    Adapts robust schemes to mean and covariance structures, providing an iteratively reweighted least squares approach to robust structural equation modeling. Each case is weighted according to its distance, based on first and second order moments. Test statistics and standard error estimators are given. (SLD)

  14. Iterative Smooth Variable Structure Filter for Parameter Estimation

    OpenAIRE

    Mohammad Al-Shabi; Saeid Habibi

    2011-01-01

    The smooth variable structure filter (SVSF) is a recently proposed predictor-corrector filter for state and parameter estimation. The SVSF is based on the sliding mode control concept. It defines a hyperplane in terms of the state trajectory and then applies a discontinuous corrective action that forces the estimate to go back and forth across that hyperplane. The SVSF is robust and stable to modeling uncertainties making it suitable for fault detection application. The discontinuous action o...

  15. Mechanical property tests on structural materials for ITER magnet system at low temperatures in China

    Science.gov (United States)

    Huang, Chuanjun; Huang, Rongjin; Li, Laifeng

    2014-01-01

    High field superconducting magnets need strong non-superconducting components for structural reinforcement. For instance, the ITER magnet system (MS) consists of cable-in-conduit conductor, coil case, magnet support, and insulating materials. Investigation of mechanical properties at magnet operation temperature with specimens machined at the final manufacturing stages of the conductor jacket materials, magnet support material, and insulating materials, even the component of the full-size conductor jacket is necessary to establish sound databases for the products. In China, almost all mechanical property tests of structural materials for the ITER MS, including conductor jacket materials of TF coils, PF coils, CCs, case material of CCs, conductor jacket materials of Main Busbars (MB) and Corrector Busbars (CB), material of magnet supports, and insulating materials of CCs have been carried out at the Technical Institute of Physics and Chemistry (TIPC), Chinese Academy of Sciences (CAS). In this paper, the mechanical property test facilities are briefly demonstrated and the mechanical tests on the structural materials for the ITER MS, highlighting test rigs as well as test methods, are presented.

  16. Pseudocontact Shift-Driven Iterative Resampling for 3D Structure Determinations of Large Proteins.

    Science.gov (United States)

    Pilla, Kala Bharath; Otting, Gottfried; Huber, Thomas

    2016-01-29

    Pseudocontact shifts (PCSs) induced by paramagnetic lanthanides produce pronounced effects in nuclear magnetic resonance spectra, which are easily measured and which deliver valuable long-range structure restraints. Even sparse PCS data greatly enhance the success rate of 3D (3-dimensional) structure predictions of proteins by the modeling program Rosetta. The present work extends this approach to 3D structures of larger proteins, comprising more than 200 residues, which are difficult to model by Rosetta without additional experimental restraints. The new algorithm improves the fragment assembly method of Rosetta by utilizing PCSs generated from paramagnetic lanthanide ions attached at four different sites as the only experimental restraints. The sparse PCS data are utilized at multiple stages, to identify native-like local structures, to rank the best structural models and to rebuild the fragment libraries. The fragment libraries are refined iteratively until convergence. The PCS-driven iterative resampling algorithm is strictly data dependent and shown to generate accurate models for a benchmark set of eight different proteins, ranging from 100 to 220 residues, using solely PCSs of backbone amide protons.

  17. Mechanical design and construction qualification program on ITER correction coils structures

    Energy Technology Data Exchange (ETDEWEB)

    Foussat, A., E-mail: arnaud.foussat@iter.org [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France); Weiyue, Wu; Jing, Wei; Shuangsong, Du [Academy of Science Institute of Plasma Physics, PO 1126, Hefei, Anhui 230031 (China); Sgobba, S. [European Center for Nuclear Research, CH-1211 Geneva 23 (Switzerland); Hongwei, Li [China International Nuclear Fusion Energy Program Execution Center, Ministry of Science and Technology, 15B Fuxing Rd., Beijing 100862 (China); Libeyre, Paul; Jong, Cornelis; Klofac, Kamil; Mitchell, Neil [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France)

    2014-04-01

    The ITER Magnet system consists of 4 main coils sub-systems, i.e. 18 toroidal field coils (TFC), a central solenoid (CS), 6 poloidal field coils (PF) and 3 sets of correction coils (CC). The ITER fusion project has selected the stainless steel 316LN as main material for the magnet structure. The CC contribute to reducing the range of magnetic error fields created by imperfections in the location and geometry of the other coils used to confine, heat, and shape the plasma. During plasma operation, a large number of loading condition scenarios have been considered and structural analysis performed on key items like Cable-In-Conduit Conductor and the coil case. The results obtained are used for both static and fatigue structural assessment defining the present baseline design. For the construction of the structural cases, welding techniques such as GTAW (Gas Tungsten Arc Welding) and techniques resulting in low distortion and shrinkage like EBW (Electron Beam Welding) or Laser Beam Welding (LBW) with filler metal wire have been selected. Those methods are considered for future qualifications to guarantee proper weld parameters and specified weld properties. In order to determine the strength and fracture toughness of 316LN stainless steel welds with respect to design criteria, some mechanical tests have been carried out at 7 K (or 77 K), and room temperature.

  18. An iterative strategy combining biophysical criteria and duration hidden Markov models for structural predictions of Chlamydia trachomatis σ66 promoters

    Directory of Open Access Journals (Sweden)

    Ojcius David M

    2009-08-01

    Full Text Available Abstract Background Promoter identification is a first step in the quest to explain gene regulation in bacteria. It has been demonstrated that the initiation of bacterial transcription depends upon the stability and topology of DNA in the promoter region as well as the binding affinity between the RNA polymerase σ-factor and promoter. However, promoter prediction algorithms to date have not explicitly used an ensemble of these factors as predictors. In addition, most promoter models have been trained on data from Escherichia coli. Although it has been shown that transcriptional mechanisms are similar among various bacteria, it is quite possible that the differences between Escherichia coli and Chlamydia trachomatis are large enough to recommend an organism-specific modeling effort. Results Here we present an iterative stochastic model building procedure that combines such biophysical metrics as DNA stability, curvature, twist and stress-induced DNA duplex destabilization along with duration hidden Markov model parameters to model Chlamydia trachomatis σ66 promoters from 29 experimentally verified sequences. Initially, iterative duration hidden Markov modeling of the training set sequences provides a scoring algorithm for Chlamydia trachomatis RNA polymerase σ66/DNA binding. Subsequently, an iterative application of Stepwise Binary Logistic Regression selects multiple promoter predictors and deletes/replaces training set sequences to determine an optimal training set. The resulting model predicts the final training set with a high degree of accuracy and provides insights into the structure of the promoter region. Model based genome-wide predictions are provided so that optimal promoter candidates can be experimentally evaluated, and refined models developed. Co-predictions with three other algorithms are also supplied to enhance reliability. Conclusion This strategy and resulting model support the conjecture that DNA biophysical properties

  19. Structural Design and Force Analysis for Equatorial Diagnostic Port Plug of ITER

    Institute of Scientific and Technical Information of China (English)

    YU Dongman; YAO Damao; XIE Han; BAO Liman; XU Tiejun; LIU Sumei

    2009-01-01

    The structural design of equatorial diagnostic port plug for international thermonuclear experimental reactor(ITER)was discussed in this paper.The induced electromagnetic (EM) loads of port plug and blanket shielding module(BSM)were presented.The finite element analysis (FEA) and numerical calculation of the system were performed under the maximum loads.According to the American Society of Mechanical Engineers(ASME)criteria,the EM stress is far below the admissible failure boundary,which indicates that the system can resist the cooperative action of EM loads and device deadweight.The analysis could provide technical data and references for further analysis and optimized design of the system.

  20. Joule heating of the ITER TF cold structure: Effects of vertical control coil currents and ELMS

    Energy Technology Data Exchange (ETDEWEB)

    Radovinsky, A.; Pillsbury, R.D. Jr.

    1993-11-09

    The toroidal field coil and support structures for ITER are maintained at cryogenic temperatures. The time-varying currents in the poloidal field coil system will induce eddy currents in these structures. The associated Joule dissipation will cause local heating and require heat removal which will show up as a load on the cryogenic system. Studies of Joule heating of the ITER TF cold structure (TFCS) due to the currents in the poloidal field coil system are presented. The two regimes considered in this study are the plasma vertical stability control and the Edge Loss Mode (ELM) events. The 3-D, thin-shell, eddy current program, EDDYCUFF was used to analyze the eddy currents and Joule losses in the cold structure. The current versus time scenarios were defined. Four control coil options were studied. All schemes use coils external to the TF cold structure. Analyses of power depositions during the plasma vertical stability control were performed for each of the four options. For each of these options three different recovery times were assumed. The times were 3, 1, and 1/3 seconds. Sets of four sequential ELMs, as well as isolated ELMs have been studied for various sets of active PF coils. The results showed that the lowest average power dissipation in the TF cold structure occurs when a subset of PF2 and PF7 are active, and all the other PF coils are passive. The general conclusion is that to minimize power dissipation in the TF cold structure it is preferable that only coils PF2 and PF7 are active. The other coils (PF3-PF6) should be passive and driven by a condition of constant flux. It is recommended in particular, that coils PF3 and PF5 be allowed to change currents to conserve flux, since they provide the maximum shielding of the TFCS from the fields caused by the active coils.

  1. Communication Skills in Candidates for Accreditation in Rheumatology Are Correlated With Candidate's Performance in the Objective Structured Clinical Examination.

    Science.gov (United States)

    Pascual-Ramos, Virginia; Flores-Alvarado, Diana Elsa; Portela-Hernández, Margarita; Maldonado-Velázquez, María Del Rocío; Amezcua-Guerra, Luis Manuel; López-Zepeda, Judith; Álvarez, Everardo; Rubio, Nadina; Lastra, Olga Vera; Saavedra, Miguel Ángel; Arce-Salinas, César Alejandro

    2017-07-26

    The Mexican Accreditation Council for Rheumatology annually certifies trainees in Rheumatology using a multiple-choice test and an objective structured clinical examination (OSCE). Since 2015, candidate's communication skills (CS) have been rated by both patients and by physician examiners and correlated with results on the OSCE. This study compared the CS from candidates to annual accreditation in Rheumatology as rated by patients and by physician examiners, and assessed whether these correlated with candidate's performance in the OSCE. From 2015 to 2017, 8areas of CS were evaluated using a Likert scale, in each OSCE station that involved a patient. Both patient and physician evaluators were trained annually and their evaluations were performed blindly. The associations were calculated using the Pearson correlation coefficient. In general, candidates were given high CS scores; the scores from patients of the candidate's CS were better than those of physician examiners; within the majority of the stations, both scores were found to correlate moderately. In addition, the scoring of CS correlated with trainee performance at the corresponding OSCE station. Interestingly, better correlations were found when the skills were rated by the patients compared to physician scores. The average CS score was correlated with the overall OSCE performance for each trainee, but not with the multiple-choice test, except in the 2017 accreditation process, when a weak correlation was found. CS assessed during a national accreditation process correlated with the candidate's performance at the station level and with the overall OSCE. Copyright © 2017 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología. All rights reserved.

  2. A simple iterative independent component analysis algorithm for vibration source signal identification of complex structures

    Directory of Open Access Journals (Sweden)

    Lee Dong-Sup

    2015-01-01

    Full Text Available Independent Component Analysis (ICA, one of the blind source separation methods, can be applied for extracting unknown source signals only from received signals. This is accomplished by finding statistical independence of signal mixtures and has been successfully applied to myriad fields such as medical science, image processing, and numerous others. Nevertheless, there are inherent problems that have been reported when using this technique: instability and invalid ordering of separated signals, particularly when using a conventional ICA technique in vibratory source signal identification of complex structures. In this study, a simple iterative algorithm of the conventional ICA has been proposed to mitigate these problems. The proposed method to extract more stable source signals having valid order includes an iterative and reordering process of extracted mixing matrix to reconstruct finally converged source signals, referring to the magnitudes of correlation coefficients between the intermediately separated signals and the signals measured on or nearby sources. In order to review the problems of the conventional ICA technique and to validate the proposed method, numerical analyses have been carried out for a virtual response model and a 30 m class submarine model. Moreover, in order to investigate applicability of the proposed method to real problem of complex structure, an experiment has been carried out for a scaled submarine mockup. The results show that the proposed method could resolve the inherent problems of a conventional ICA technique.

  3. Numerical modeling of 3D halo current path in ITER structures

    Energy Technology Data Exchange (ETDEWEB)

    Bettini, Paolo; Marconato, Nicolò; Furno Palumbo, Maurizio; Peruzzo, Simone [Consorzio RFX, EURATOM-ENEA Association, C.so Stati Uniti 4, 35127 Padova (Italy); Specogna, Ruben, E-mail: ruben.specogna@uniud.it [DIEGM, Università di Udine, Via delle Scienze, 208, 33100 Udine (Italy); Albanese, Raffaele; Rubinacci, Guglielmo; Ventre, Salvatore; Villone, Fabio [Consorzio CREATE, EURATOM-ENEA Association, Via Claudio 21, 80125 Napoli (Italy)

    2013-10-15

    Highlights: ► Two numerical codes for the evaluation of halo currents in 3D structures are presented. ► A simplified plasma model is adopted to provide the input (halo current injected into the FW). ► Two representative test cases of ITER symmetric and asymmetric VDEs have been analyzed. ► The proposed approaches provide results in excellent agreement for both cases. -- Abstract: Disruptions represent one of the main concerns for Tokamak operation, especially in view of fusion reactors, or experimental test reactors, due to the electro-mechanical loads induced by halo and eddy currents. The development of a predictive tool which allows to estimate the magnitude and spatial distribution of the halo current forces is of paramount importance in order to ensure robust vessel and in-vessel component design. With this aim, two numerical codes (CARIDDI, CAFE) have been developed, which allow to calculate the halo current path (resistive distribution) in the passive structures surrounding the plasma. The former is based on an integral formulation for the eddy currents problem particularized to the static case; the latter implements a pair of 3D FEM complementary formulations for the solution of the steady-state current conduction problem. A simplified plasma model is adopted to provide the inputs (halo current injected into the first wall). Two representative test cases (ITER symmetric and asymmetric VDEs) have been selected to cross check the results of the proposed approaches.

  4. Iterative ramp sharpening for structure signature-preserving simplification of images

    Energy Technology Data Exchange (ETDEWEB)

    Grazzini, Jacopo A [Los Alamos National Laboratory; Soille, Pierre [EC-JRC

    2010-01-01

    In this paper, we present a simple and heuristic ramp sharpening algorithm that achieves local contrast enhancement of vector-valued images. The proposed algorithm performs a local comparison of intensity values as well as gradient strength and directional information derived from the gradient structure tensor so that the sharpening is applied only for pixels found on the ramps around true edges. This way, the contrast between objects and regions separated by a ramp is enhanced correspondingly, avoiding ringing artefacts. It is found that applying this technique in an iterative manner on blurred imagery produces sharpening preserving both structure and signature of the image. The final approach reaches a good compromise between complexity and effectiveness for image simplification, enhancing in an efficient manner the image details and maintaining the overall image appearance.

  5. Iterative structure-based peptide-like inhibitor design against the botulinum neurotoxin serotype A.

    Directory of Open Access Journals (Sweden)

    Jorge E Zuniga

    Full Text Available The botulinum neurotoxin serotype A light chain (BoNT/A LC protease is the catalytic component responsible for the neuroparalysis that is characteristic of the disease state botulism. Three related peptide-like molecules (PLMs were designed using previous information from co-crystal structures, synthesized, and assayed for in vitro inhibition against BoNT/A LC. Our results indicate these PLMS are competitive inhibitors of the BoNT/A LC protease and their K(i values are in the nM-range. A co-crystal structure for one of these inhibitors was determined and reveals that the PLM, in accord with the goals of our design strategy, simultaneously involves both ionic interactions via its P1 residue and hydrophobic contacts by means of an aromatic group in the P2' position. The PLM adopts a helical conformation similar to previously determined co-crystal structures of PLMs, although there are also major differences to these other structures such as contacts with specific BoNT/A LC residues. Our structure further demonstrates the remarkable plasticity of the substrate binding cleft of the BoNT/A LC protease and provides a paradigm for iterative structure-based design and development of BoNT/A LC inhibitors.

  6. Newton`s iteration for inversion of Cauchy-like and other structured matrices

    Energy Technology Data Exchange (ETDEWEB)

    Pan, V.Y. [Lehman College, Bronx, NY (United States); Zheng, Ailong; Huang, Xiaohan; Dias, O. [CUNY, New York, NY (United States)

    1996-12-31

    We specify some initial assumptions that guarantee rapid refinement of a rough initial approximation to the inverse of a Cauchy-like matrix, by mean of our new modification of Newton`s iteration, where the input, output, and all the auxiliary matrices are represented with their short generators defined by the associated scaling operators. The computations are performed fast since they are confined to operations with short generators of the given and computed matrices. Because of the known correlations among various structured matrices, the algorithm is immediately extended to rapid refinement of rough initial approximations to the inverses of Vandermonde-like, Chebyshev-Vandermonde-like and Toeplitz-like matrices, where again, the computations are confined to operations with short generators of the involved matrices.

  7. Final design of the generic upper port plug structure for ITER diagnostic systems

    Energy Technology Data Exchange (ETDEWEB)

    Pak, Sunil, E-mail: paksunil@nfri.re.kr [National Fusion Research Institute, Daejeon (Korea, Republic of); Feder, Russell [Princeton Plasma Physics Laboratory, Princeton, NJ (United States); Giacomin, Thibaud; Guirao, Julio; Iglesias, Silvia; Josseaume, Fabien [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-lez-Durance (France); Kalish, Michael; Loesser, Douglas [Princeton Plasma Physics Laboratory, Princeton, NJ (United States); Maquet, Philippe [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-lez-Durance (France); Ordieres, Javier; Panizo, Marcos [NATEC, Ingenieros, Gijón (Spain); Pitcher, Spencer; Portalès, Mickael [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-lez-Durance (France); Proust, Maxime [CEA, Cadarache, St. Paul-lez-Durance (France); Ronden, Dennis [FOM Institute DIFFER, Nieuwegein (Netherlands); Serikov, Arkady [Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen (Germany); Suarez, Alejandro [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-lez-Durance (France); Tanchuk, Victor [NIIEFA, St.-Petersburg (Russian Federation); Udintsev, Victor; Vacas, Christian [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-lez-Durance (France); and others

    2016-01-15

    The generic upper port plug (GUPP) structure in ITER is a 6 m long metal box which deploys diagnostic components into the vacuum vessel. This structure is commonly used for all the diagnostic upper ports. The final design of the GUPP structure, which has successfully passed the final design review in 2013, is described here. The diagnostic port plug is cantilevered to the vacuum vessel with a heavy payload at the front, so called the diagnostic first wall (DFW) and the diagnostic shield module (DSM). Most of electromagnetic (EM) load (∼80%) occurs in DFW/DSM. Therefore, the mounting design to transfer the EM load from DFW/DSM to the GUPP structure is challenging, which should also comply with thermal expansion and tolerance for assembly and manufacturing. Another key design parameter to be considered is the gap between the port plug and the vacuum vessel port. The gap should be large enough to accommodate the remote handling of the heavy port plug (max. 25 t), the structural deflection due to external loads and machine assembly tolerance. At the same time, the gap should be minimized to stop the neutron streaming according to the ALARA (as low as reasonably achievable) principle. With these design constraints, the GUPP structure should also provide space for diagnostic integration as much as possible. This requirement has led to the single wall structure having the gun-drilled water channels inside the structure. Furthermore, intensive efforts have been made on the manufacturing study including material selection, manufacturing codes and French regulation related to nuclear equipment and safety. All these main design and manufacturing aspects are discussed in this paper, including requirements, interfaces, loads and structural assessment and maintenance.

  8. European cryogenic material testing program for ITER coils and intercoil structures

    Science.gov (United States)

    Nyilas, A.; Portone, A.; Kiesel, H.

    2002-05-01

    The following materials were characterized for the use in the magnet structures of ITER: 1) Type 316LN cast materials having a modified chemistry used for a Model of the TF (Toroidal Field) outer intercoil structure were investigated with respect to tensile, fracture, fatigue crack growth rate (FCGR), and fatigue life behavior between 7 and 4 K. 2) For Type 316LN 80 mm thick plate used for the TFMC (T_oroidal F_ield M_odel C_oil) structure a complete cryogenic mechanical materials characterization was established. 3) For full size coil case mockups, repair weld properties of 240 mm thick narrow-gap welds were investigated to determine their tensile and fracture behavior. 4) For CSMC (C_enter S_olenoid M_odel C_oil) superconductor jackets, the fatigue lives of orbital butt welds made of Incoloy 908 and Type 316LN (aged and unaged) materials were determined up to one million cycles at 7 K. The results reveal to date that the FCGR of aged Type 316LN is inferior to Incoloy 908 material, whilst the fatigue life properties are comparable. However, for Type 316LN jacket structure considerable improvement of FCGR could be achieved by a solution heat treatment process. In addition, tensile and fatigue life tests performed with a new cryogenic mechanical test facility (630 kN capacity) are presented.

  9. Structural insight into the tetramerization of an iterative ketoreductase siam through aromatic residues in the interfaces.

    Science.gov (United States)

    Wang, Hua; Zhang, Huaidong; Zou, Yi; Mi, Yanling; Lin, Shuangjun; Xie, Zhixiong; Yan, Yunjun; Zhang, Houjin

    2014-01-01

    In the biosynthesis of polyketides, ketoreductases (KRs) are an important group of enzymes that determine the chiralities of the carbon backbones. SiaM is a special member of this group that can recognize substrates with different lengths and can be used iteratively. Here we report the crystal structure of SiaM. Structural analysis indicates that the overall structure resembles those of other KRs. However, significant disparity can be found in the conserved LDD motif that is replaced with IRD motif in SiaM. The isoleucine and aspartic acid residues take similar orientations as leucine and aspartic acid in the conserved LDD motif, while the arginine residue points out towards the solvent. PISA analysis shows that SiaM forms a tetramer. Several aromatic residues are found in the interfaces, which have aromatic stacking interactions with the aromatic residues in the neighboring protomers. Mutagenesis studies performed on the aromatic residues show that these sites are important for maintaining the structural integrity of SiaM. However, the aromatic residues contribute differently to the enzymatic activity. In the N-terminal interface, the aromatic residues can be replaced with leucine without affecting the enzymatic activity while, in the other interface, such mutations abolish the enzymatic activity.

  10. Iterative model-building, structure refinement, and density modification with the PHENIX AutoBuild Wizard

    Energy Technology Data Exchange (ETDEWEB)

    Los Alamos National Laboratory, Mailstop M888, Los Alamos, NM 87545, USA; Lawrence Berkeley National Laboratory, One Cyclotron Road, Building 64R0121, Berkeley, CA 94720, USA; Department of Haematology, University of Cambridge, Cambridge CB2 0XY, England; Terwilliger, Thomas; Terwilliger, T.C.; Grosse-Kunstleve, Ralf Wilhelm; Afonine, P.V.; Moriarty, N.W.; Zwart, P.H.; Hung, L.-W.; Read, R.J.; Adams, P.D.

    2007-04-29

    The PHENIX AutoBuild Wizard is a highly automated tool for iterative model-building, structure refinement and density modification using RESOLVE or TEXTAL model-building, RESOLVE statistical density modification, and phenix.refine structure refinement. Recent advances in the AutoBuild Wizard and phenix.refine include automated detection and application of NCS from models as they are built, extensive model completion algorithms, and automated solvent molecule picking. Model completion algorithms in the AutoBuild Wizard include loop-building, crossovers between chains in different models of a structure, and side-chain optimization. The AutoBuild Wizard has been applied to a set of 48 structures at resolutions ranging from 1.1 {angstrom} to 3.2 {angstrom}, resulting in a mean R-factor of 0.24 and a mean free R factor of 0.29. The R-factor of the final model is dependent on the quality of the starting electron density, and relatively independent of resolution.

  11. Investigation of Iterative Algorithms for Evaluation of Capital Structure and Cost

    Directory of Open Access Journals (Sweden)

    Vigen Minasyan

    2014-01-01

    Full Text Available Determination of structure and correct calculation of a company’s capital value is an essential; theoretical and practical problem for corporate finance. The proportion between the company’s equity and borrowed capital determines the risk and profitability of the company and, consequently, the welfare of its owners. The most common recommendation is to evaluate the stricture of capital based on market proportions between indebtedness and equity. However, market proportions most often deviate from values obtained through analytical calculations. This means that weak efficiency of the market brings about inconsistency between the input data and the results, which are calculated from them. Second, not all companies have a representative market quotation. There is a question, then: how can we correctly evaluate capital and its market structure for individual projects and companies in general? The work presented below is dedicated to the iterative method for evaluation of fair structure of capital as suggested in (Limitovsky M.A., Minasyan V.B. 2010, and to the proving of consistency of this method for a very large number of companies.

  12. An Iterative Inversion Technique to Compute Structural Martian Models for Refining Event Locations

    Science.gov (United States)

    Ceylan, S.; Khan, A.; van Driel, M.; Clinton, J. F.; Boese, M.; Euchner, F.; Giardini, D.; Garcia, R.; Lognonne, P. H.; Panning, M. P.; Banerdt, W. B.

    2016-12-01

    The InSight mission will deploy a single seismic station on Mars in 2018. The main task of the MarsQuake Service within the project includes detecting and locating quakes on Mars, and managing the event catalog. In preparation for the mission, we continually calibrate single station event location algorithms, employing seismic phase travel times computed for a suite of structural models. However, our knowledge about the interior structure of Mars is limited, which in turn will affect our ability to locate events accurately. Here, we present an iterative method to invert for the interior structure of Mars and revise event locations, consecutively. We first locate seismic events using differential arrival times (with respect to the first phase arrival) of all possible seismic phases, computed for a priori initial structural models. These models are built considering a one-dimensional average crust and current estimates of bulk mantle chemistry and areotherm. Phase picks and uncertainty assignments are done manually. Then, we invert for the interior structure employing the arrival times for the picked phases, and generate an updated suite of models, which are further used to revise the initial phase picks, and relocate events. We repeat this sequence for each additional and new entry in the travel time database to improve event locations and models for average Martian structure. In order to test our approach, we simulate the operational conditions we will encounter in practice: We compute synthetic waveforms for a realistic event catalog of 120 events, with magnitudes between 2.5 and 5.0 and double-couple source mechanisms only. 1-Hz seismograms are computed using AxiSEM and Instaseis, employing two Martian models with a thin (30 km) and thick (80 km) crust, both with and without seismic surface noise. The waveforms are hosted at the ETH servers, and are publicly accessible via FDSN web services.

  13. Intriguing structures in iterative maps motivated by N-body problem

    Science.gov (United States)

    Mittal, Ashok Kumar; Gupta, Ashok Kumar

    2011-03-01

    Conventional approaches to modeling any system try to incorporate increasingly realistic features into the model, thereby making it more and more complex. An opposite approach seeks to build simpler and simpler conceptual models capable of capturing some observed features of a system. This trend began with Lorenz, who simplified models of the atmosphere to obtain the Lorenz model consisting of a system of only three equations. Despite the simplicity of these equations, this system displayed surprisingly rich properties, and has been used as a conceptual model in diverse disciplines. Poincare maps help study ordinary differential equations from a qualitative perspective. Several investigators like Henon and Feigenbaum followed this simplification approach. Instead of investigating Poincare maps of realistic systems, they, along with several others, investigated simple maps for their own sake. Despite lack of realism, this approach proved to be very fruitful. A map, as simple as the Logistic map, became an important conceptual modeling paradigm. It provided a tool for understanding bifurcation routes to chaos, which were verified experimentally through various experiments in diverse fields. Coupled map lattices (CML) help explore partial differential equations (PDE). Further simplification led to the introduction of Cellular Automata (CA). These fields continue to be explored with vigor and have given rise to a rich body of knowledge, conceptually useful over a wide spectrum of disciplines. In this paper, we follow the simplification approach for modeling the N-body problem. N-body simulations, say in Gravitation, give rise to filamentary structures. Such structures are observed in the actual observed Galactic distribution. The mechanism for creation of such structures is not well understood. We present a simple iterative dynamical model, motivated by the N-body problem, which, though unrealistic, produces such filamentary structures. This model also exhibits a

  14. Main-Branch Structure Iterative Detection Using Approximate Message Passing for Uplink Large-Scale Multiuser MIMO Systems

    Directory of Open Access Journals (Sweden)

    Qifeng Zou

    2016-01-01

    Full Text Available The emerging large-scale/massive multi-input multioutput (MIMO system combined with orthogonal frequency division multiplexing (OFDM is considered a key technology for its advantage of improving the spectral efficiency. In this paper, we introduce an iterative detection algorithm for uplink large-scale multiuser MIMO-OFDM communication systems. We design a Main-Branch structure iterative turbo detector using the Approximate Message Passing algorithm simplified by linear approximation (AMP-LA and using the Mean Square Error (MSE criterion to calculate the correlation coefficients between main detector and branch detector for the given iteration. The complexity of our method is compared with other detection algorithms. The simulation results show that our scheme can achieve better performance than the conventional detection methods and have the acceptable complexity.

  15. Structure and kinematics of candidate double-barred galaxies

    CERN Document Server

    Moiseev, A V; Chavushyan, V H

    2003-01-01

    Results of optical and NIR spectral and photometric observations of a sample of candidate double-barred galaxies are presented. Velocity fields and velocity dispersion maps of stars and ionized gas, continuum and emission-line images were constructed from integral-field spectroscopy observations carried out at the 6m telescope (BTA) of SAO RAS, with the MPFS spectrograph and the scanning Fabry-Perot Interferometer. NGC2681 was also observed with long-slit spectrograph of the BTA. Optical and NIR images were obtained at the BTA and at the 2.1m telescope (OAN, M\\'exico). High-resolution images were retrieved from the HST data archive. Morphological and kinematic features of all 13 sample objects are described in detail. Attention is focused on the interpretation of observed non-circular motions of gas and stars in circumnuclear (one kiloparsec- scale) regions. We have shown first of all that these motions are caused by a gravitational potential of large-scale bar. NGC3368 and NGC3786 have nuclear bars only, the...

  16. Determining the Cognitive Structures of Geography Teacher Candidates on "Earthquake"

    Science.gov (United States)

    Kaya, Bastürk; Aladag, Caner

    2017-01-01

    The objective of this study is to determine the cognitive structures of the students of geography teaching department by identifying their conceptual frameworks about the concept of earthquake. A case study design from qualitative research approaches was used in this research. Sample group of the study constitutes 155 students from the Department…

  17. Reduced activation martensitic steels as a structural material for ITER test blanket

    Energy Technology Data Exchange (ETDEWEB)

    Shiba, K. E-mail: shiba@realab01.tokai.jaeri.go.jp; Enoeda, M.; Jitsukawa, S

    2004-08-01

    A Japanese ITER test blanket module (TBM) is planed to use reduced-activation martensitic steel F82H. Feasibility of F82H for ITER test blanket module is discussed in this paper. Several kinds of property data, including physical properties, magnetic properties, mechanical properties and neutron-irradiation data on F82H have been obtained, and these data are complied into a database to be used for the designing of the ITER TBM. Currently obtained data suggests F82H will not have serious problems for ITER TBM. Optimization of F82H improves the induced activity, toughness and HIP resistance. Furthermore, modified F82H is resistant to temperature instability during material production.

  18. Validation and implementation of sandwich structure bottom plate to rib weld joint in the base section of ITER Cryostat

    Energy Technology Data Exchange (ETDEWEB)

    Prajapati, Rajnikant, E-mail: rajnikant@iter-india.org [ITER-India, Institute For Plasma Research, A-29, GIDC Electronics Estate, Sector-25, Gandhinagar 382016 (India); Bhardwaj, Anil K.; Gupta, Girish; Joshi, Vaibhav; Patel, Mitul; Bhavsar, Jagrut; More, Vipul; Jindal, Mukesh; Bhattacharya, Avik; Jogi, Gaurav; Palaliya, Amit; Jha, Saroj; Pandey, Manish [ITER-India, Institute For Plasma Research, A-29, GIDC Electronics Estate, Sector-25, Gandhinagar 382016 (India); Jadhav, Pandurang; Desai, Hemal [Larsen & Toubro Limited, Heavy Engineering, Hazira Manufacturing Complex, Gujarat (India)

    2016-11-01

    Highlights: • ITER Cryostat base section sandwich structure bottom plate to rib weld joint is qualified through mock-up. • Established welding sequence was successfully implemented on all six sectors of cryostat base section. • Each layer liquid penetrant examination has been carried out for these weld joints and found satisfactory. - Abstract: Cryostat is a large stainless steel vacuum vessel providing vacuum environment to ITER machine components. The cryostat is ∼30 m in diameter and ∼30 m in height having variable thickness from 25 mm to 180 mm. Sandwich structure of cryostat base section withstands vacuum loading and limits the deformation under service conditions. Sandwich structure consists of top and bottom plates internally strengthened with radial and circular ribs. In current work, sandwich structure bottom plate to rib weld joint has been designed with full penetration joint as per ITER Vacuum Handbook requirement considering nondestructive examinations and welding feasibility. Since this joint was outside the scope of ASME Section VIII Div. 2, it was decided to validate through mock-up of bottom plate to rib joint. Welding sequence was established to control the distortion. Tensile test, macro-structural examination and layer by layer LPE were carried out for validation of this weld joint. However possibility of ultrasonic examination method was also investigated. The test results from the welded joint mock-up were found to confirm all code and specification requirements. The same was implemented in first sector (0–60°) of base section sandwich structure.

  19. Improving prediction of secondary structure, local backbone angles, and solvent accessible surface area of proteins by iterative deep learning.

    Science.gov (United States)

    Heffernan, Rhys; Paliwal, Kuldip; Lyons, James; Dehzangi, Abdollah; Sharma, Alok; Wang, Jihua; Sattar, Abdul; Yang, Yuedong; Zhou, Yaoqi

    2015-01-01

    Direct prediction of protein structure from sequence is a challenging problem. An effective approach is to break it up into independent sub-problems. These sub-problems such as prediction of protein secondary structure can then be solved independently. In a previous study, we found that an iterative use of predicted secondary structure and backbone torsion angles can further improve secondary structure and torsion angle prediction. In this study, we expand the iterative features to include solvent accessible surface area and backbone angles and dihedrals based on Cα atoms. By using a deep learning neural network in three iterations, we achieved 82% accuracy for secondary structure prediction, 0.76 for the correlation coefficient between predicted and actual solvent accessible surface area, 19° and 30° for mean absolute errors of backbone φ and ψ angles, respectively, and 8° and 32° for mean absolute errors of Cα-based θ and τ angles, respectively, for an independent test dataset of 1199 proteins. The accuracy of the method is slightly lower for 72 CASP 11 targets but much higher than those of model structures from current state-of-the-art techniques. This suggests the potentially beneficial use of these predicted properties for model assessment and ranking.

  20. Corrosion mechanisms of candidate structural materials for supercritical water-cooled reactor

    Institute of Scientific and Technical Information of China (English)

    Lefu ZHANG; Fawen ZHU; Rui TANG

    2009-01-01

    Nickel-based alloys, austenitic stainless steel, ferritic/martensitic heat-resistant steels, and oxide dispersion strengthened steel are presently considered to be the candidate structural or fuel-cladding materials for supercritical water-cooled reactor (SCWR), one of the promising generation IV reactor for large-scale electric power production. However, corrosion and stress corrosion cracking of these candidate alloys still remain to be a major problem in the selection of nuclear fuel cladding and other structural materials, such as water rod. Survey of literature and experimental results reveal that the general corrosion mechanism of those candidate materials exhibits quite complicated mechanism in high-temperature and high-pressure supercritical water. Formation of a stable protective oxide film is the key to the best corrosion-resistant alloys. This paper focuses on the mechanism of corrosion oxide film breakdown for SCWR candidate materials.

  1. Evaluations of Structural Failure Probabilities and Candidate Inservice Inspection Programs

    Energy Technology Data Exchange (ETDEWEB)

    Khaleel, Mohammad A.; Simonen, Fredric A.

    2009-05-01

    The work described in this report applies probabilistic structural mechanics models to predict the reliability of nuclear pressure boundary components. These same models are then applied to evaluate the effectiveness of alternative programs for inservice inspection to reduce these failure probabilities. Results of the calculations support the development and implementation of risk-informed inservice inspection of piping and vessels. Studies have specifically addressed the potential benefits of ultrasonic inspections to reduce failure probabilities associated with fatigue crack growth and stress-corrosion cracking. Parametric calculations were performed with the computer code pc-PRAISE to generate an extensive set of plots to cover a wide range of pipe wall thicknesses, cyclic operating stresses, and inspection strategies. The studies have also addressed critical inputs to fracture mechanics calculations such as the parameters that characterize the number and sizes of fabrication flaws in piping welds. Other calculations quantify uncertainties associated with the inputs calculations, the uncertainties in the fracture mechanics models, and the uncertainties in the resulting calculated failure probabilities. A final set of calculations address the effects of flaw sizing errors on the effectiveness of inservice inspection programs.

  2. Discrete self-similarity in thin films with van der Waals interactions and the formation of iterated structures

    CERN Document Server

    Dallaston, Michael C; Tseluiko, Dmitri; Kalliadasis, Serafim

    2016-01-01

    The formation of iterated structures, such as satellite and sub-satellite drops, filaments, bubbles, etc is a common phenomenon in free surface flows. We provide a computational and theoretical study of the origin of these patterns in the case of thin films of viscous fluids subject to long-range molecular forces. Iterated structures appear as a consequence of discrete self-similarity, where patterns repeat themselves, subject to rescaling, periodically in a logarithmic time scale. The result is an infinite sequence of ridges and filaments with similarity properties. The character of these discretely self-similar solutions as the result of a Hopf bifurcation from ordinarily self-similar solutions is also described.

  3. A three-dimensional measurement method based on mesh candidates assisted with structured light

    Science.gov (United States)

    Xu, Gang; Zhang, Wenming; Li, Haibin; Liu, Bin

    2009-07-01

    Rendering three-dimensional information of a scene from optical measurement is very important for a wide variety of applications such as robot navigation, rapid prototyping, medical imaging, industrial inspection, etc. In this paper, a new 3D measurement method based on mesh candidate with structured light illuminating is proposed. The vision sensor consists of two CCD cameras and a DLP projector. The measurement system combines the technology of binocular stereo vision and structured light, so as to simplify the process of acquiring depth information using mesh candidates. The measurement method is based on mesh candidates which represent the potential depth in the three dimensional scene. First the mesh grid was created along the direction of axes in world coordinate system, and the nodes were considered as depth candidates on the surface of object. Then each group of the mesh nodes varying along z axis were mapped to the captured image planes of both cameras. At last, according to the similarity measure of the corresponding pixel pairs, the depth of the object surface can be obtained. The matching process is between the pixels in both camera planes corresponding to the spatial mesh candidates. Aided by the structured light pattern, the accuracy of measurement system improved. Appending the periodic sawtooth pattern on the scene by structured light made measurement easier, while the computational cost did not increased since the projector had no need to be calibrated. The 3DS MAX and Matlab software were used to simulate measurement system and reconstruct the surface of the object. After the positioned cameras have been calibrated using Matlab calibration toolbox, the projector is used to project structured light pattern on the scene. Indicated by experimental results, the mesh-candidate-based method is obviously superior in computation and accuracy. Compared with traditional methods based on image matching, our method has several advantages: (1) the complex

  4. Iterative methods for obtaining solvation structures on a solid plate: The methods for Surface Force Apparatus and Atomic Force Microscopy in Liquids

    CERN Document Server

    Amano, Ken-ich

    2013-01-01

    We propose iterative methods for obtaining solvation structures on a solid plate which use force distributions measured by surface force apparatus (SFA) and atomic force microscopy (AFM) as input data. Two model systems are considered here. In the model system for SFA, the same two solid plates are immersed in a solvent, and a probe tip and a solid plate are immersed in a solvent in the model system for AFM. Advantages of the iterative methods are as follows: The iterative method for SFA can obtain the solvation structure, for example, in a Lennard-Jones liquid; The iterative method for AFM can obtain the solvation structure without an input datum of solvation structure around the probe tip.

  5. Upper-Lower Bounds Candidate Sets Searching Algorithm for Bayesian Network Structure Learning

    Directory of Open Access Journals (Sweden)

    Guangyi Liu

    2014-01-01

    Full Text Available Bayesian network is an important theoretical model in artificial intelligence field and also a powerful tool for processing uncertainty issues. Considering the slow convergence speed of current Bayesian network structure learning algorithms, a fast hybrid learning method is proposed in this paper. We start with further analysis of information provided by low-order conditional independence testing, and then two methods are given for constructing graph model of network, which is theoretically proved to be upper and lower bounds of the structure space of target network, so that candidate sets are given as a result; after that a search and scoring algorithm is operated based on the candidate sets to find the final structure of the network. Simulation results show that the algorithm proposed in this paper is more efficient than similar algorithms with the same learning precision.

  6. Augmented weak forms and element-by-element preconditioners: Efficient iterative strategies for structural finite elements. A preliminary study

    Science.gov (United States)

    Muller, A.; Hughes, T. J. R.

    1984-01-01

    A weak formulation in structural analysis that provides well conditioned matrices suitable for iterative solutions is presented. A mixed formulation ensures the proper representation of the problem and the constitutive relations are added in a penalized form. The problem is solved by a double conjugate gradient algorithm combined with an element by element approximate factorization procedure. The double conjugate gradient strategy resembles Uzawa's variable-length type algorithms the main difference is the presence of quadratic terms in the mixed variables. In the case of shear deformable beams these terms ensure that the proper finite thickness solution is obtained.

  7. Iterative Maps with Hierarchical Clustering for the Observed Scales of Astrophysical and Cosmological Structures

    CERN Document Server

    Capozziello, S; De Siena, S; Guerra, F; Illuminati, F

    2000-01-01

    We derive, in order of magnitude, the observed astrophysical and cosmologicalscales in the Universe, from neutron stars to superclusters of galaxies, up to,asymptotically, the observed radius of the Universe. This result is obtained byintroducing a recursive scheme of alternating hierachical mechanisms ofthree-dimensional and two-dimensional close packings of gravitationallyinteracting objects. The iterative scheme yields a rapidly converging geometricsequence, which can be described as a hierarchical clustering of aggregates,having the observed radius of the Universe as its fixed point.

  8. Determination of J-resistance curves of nuclear structure materials by iteration method

    Energy Technology Data Exchange (ETDEWEB)

    Byun, Thak Sang; Lee, Bong Sang; Yoon, Ji Hyun; Kuk, Il Hiun; Hong, Jun Hwa [KAERI, Taejon (Korea, Republic of)

    1998-05-01

    An iteration method has been developed for determining crack growth and fracture resistance curve (J-R curve) from the load versus load-line displacement record only. In this method, the hardening curve, the load versus displacement curve at a given crack length, is assumed to be a power-law function, where the exponent varies with the crack length. The exponent is determined by an interative calculation method with the assumption that the exponent varies linearly with the load-line displacement. The proposed method was applied to the static J-R tests using compact tension (CT) specimens, a three-point bend (TPB) specimen, and a cracked round bar (CRB) specimen as well as it was applied to the quasi-dynamic J-R tests using CT specimens. The J-R curves determined by the proposed method were compared with those obtained by the conventional testing methodologies. The results showed that the J-R curves could be determined directly by the proposed iteration method with sufficient accuracy in the specimens from SA508, SA533, and SA516 pressure vessel steels and SA312 Type 347 stainless steel.

  9. Chebyshev polynomial filtered subspace iteration in the discontinuous Galerkin method for large-scale electronic structure calculations

    Science.gov (United States)

    Banerjee, Amartya S.; Lin, Lin; Hu, Wei; Yang, Chao; Pask, John E.

    2016-10-01

    The Discontinuous Galerkin (DG) electronic structure method employs an adaptive local basis (ALB) set to solve the Kohn-Sham equations of density functional theory in a discontinuous Galerkin framework. The adaptive local basis is generated on-the-fly to capture the local material physics and can systematically attain chemical accuracy with only a few tens of degrees of freedom per atom. A central issue for large-scale calculations, however, is the computation of the electron density (and subsequently, ground state properties) from the discretized Hamiltonian in an efficient and scalable manner. We show in this work how Chebyshev polynomial filtered subspace iteration (CheFSI) can be used to address this issue and push the envelope in large-scale materials simulations in a discontinuous Galerkin framework. We describe how the subspace filtering steps can be performed in an efficient and scalable manner using a two-dimensional parallelization scheme, thanks to the orthogonality of the DG basis set and block-sparse structure of the DG Hamiltonian matrix. The on-the-fly nature of the ALB functions requires additional care in carrying out the subspace iterations. We demonstrate the parallel scalability of the DG-CheFSI approach in calculations of large-scale two-dimensional graphene sheets and bulk three-dimensional lithium-ion electrolyte systems. Employing 55 296 computational cores, the time per self-consistent field iteration for a sample of the bulk 3D electrolyte containing 8586 atoms is 90 s, and the time for a graphene sheet containing 11 520 atoms is 75 s.

  10. Detecting protein candidate fragments using a structural alphabet profile comparison approach.

    Directory of Open Access Journals (Sweden)

    Yimin Shen

    Full Text Available Predicting accurate fragments from sequence has recently become a critical step for protein structure modeling, as protein fragment assembly techniques are presently among the most efficient approaches for de novo prediction. A key step in these approaches is, given the sequence of a protein to model, the identification of relevant fragments - candidate fragments - from a collection of the available 3D structures. These fragments can then be assembled to produce a model of the complete structure of the protein of interest. The search for candidate fragments is classically achieved by considering local sequence similarity using profile comparison, or threading approaches. In the present study, we introduce a new profile comparison approach that, instead of using amino acid profiles, is based on the use of predicted structural alphabet profiles, where structural alphabet profiles contain information related to the 3D local shapes associated with the sequences. We show that structural alphabet profile-profile comparison can be used efficiently to retrieve accurate structural fragments, and we introduce a fully new protocol for the detection of candidate fragments. It identifies fragments specific of each position of the sequence and of size varying between 6 and 27 amino-acids. We find it outperforms present state of the art approaches in terms (i of the accuracy of the fragments identified, (ii the rate of true positives identified, while having a high coverage score. We illustrate the relevance of the approach on complete target sets of the two previous Critical Assessment of Techniques for Protein Structure Prediction (CASP rounds 9 and 10. A web server for the approach is freely available at http://bioserv.rpbs.univ-paris-diderot.fr/SAFrag.

  11. Chebyshev polynomial filtered subspace iteration in the Discontinuous Galerkin method for large-scale electronic structure calculations

    CERN Document Server

    Banerjee, Amartya S; Hu, Wei; Yang, Chao; Pask, John E

    2016-01-01

    The Discontinuous Galerkin (DG) electronic structure method employs an adaptive local basis set to solve the equations of density functional theory in a discontinuous Galerkin framework. The methodology is implemented in the Discontinuous Galerkin Density Functional Theory (DGDFT) code for large-scale parallel electronic structure calculations. In DGDFT, the basis is generated on-the-fly to capture the local material physics, and can systematically attain chemical accuracy with only a few tens of degrees of freedom per atom. Hence, DGDFT combines the key advantage of planewave basis sets in terms of systematic improvability with that of localized basis sets in reducing basis size. A central issue for large-scale calculations, however, is the computation of the electron density from the discretized Hamiltonian in an efficient and scalable manner. We show in this work how Chebyshev polynomial filtered subspace iteration (CheFSI) can be used to address this issue and push the envelope in large-scale materials si...

  12. In Vitro Evolution of Allergy Vaccine Candidates, with Maintained Structure, but Reduced B Cell and T Cell Activation Capacity

    Science.gov (United States)

    Nilsson, Ola B.; Adedoyin, Justus; Rhyner, Claudio; Neimert-Andersson, Theresa; Grundström, Jeanette; Berndt, Kurt D.; Crameri, Reto; Grönlund, Hans

    2011-01-01

    Allergy and asthma to cat (Felis domesticus) affects about 10% of the population in affluent countries. Immediate allergic symptoms are primarily mediated via IgE antibodies binding to B cell epitopes, whereas late phase inflammatory reactions are mediated via activated T cell recognition of allergen-specific T cell epitopes. Allergen-specific immunotherapy relieves symptoms and is the only treatment inducing a long-lasting protection by induction of protective immune responses. The aim of this study was to produce an allergy vaccine designed with the combined features of attenuated T cell activation, reduced anaphylactic properties, retained molecular integrity and induction of efficient IgE blocking IgG antibodies for safer and efficacious treatment of patients with allergy and asthma to cat. The template gene coding for rFel d 1 was used to introduce random mutations, which was subsequently expressed in large phage libraries. Despite accumulated mutations by up to 7 rounds of iterative error-prone PCR and biopanning, surface topology and structure was essentially maintained using IgE-antibodies from cat allergic patients for phage enrichment. Four candidates were isolated, displaying similar or lower IgE binding, reduced anaphylactic activity as measured by their capacity to induce basophil degranulation and, importantly, a significantly lower T cell reactivity in lymphoproliferative assays compared to the original rFel d 1. In addition, all mutants showed ability to induce blocking antibodies in immunized mice.The approach presented here provides a straightforward procedure to generate a novel type of allergy vaccines for safer and efficacious treatment of allergic patients. PMID:21931754

  13. In vitro evolution of allergy vaccine candidates, with maintained structure, but reduced B cell and T cell activation capacity.

    Directory of Open Access Journals (Sweden)

    Ola B Nilsson

    Full Text Available Allergy and asthma to cat (Felis domesticus affects about 10% of the population in affluent countries. Immediate allergic symptoms are primarily mediated via IgE antibodies binding to B cell epitopes, whereas late phase inflammatory reactions are mediated via activated T cell recognition of allergen-specific T cell epitopes. Allergen-specific immunotherapy relieves symptoms and is the only treatment inducing a long-lasting protection by induction of protective immune responses. The aim of this study was to produce an allergy vaccine designed with the combined features of attenuated T cell activation, reduced anaphylactic properties, retained molecular integrity and induction of efficient IgE blocking IgG antibodies for safer and efficacious treatment of patients with allergy and asthma to cat. The template gene coding for rFel d 1 was used to introduce random mutations, which was subsequently expressed in large phage libraries. Despite accumulated mutations by up to 7 rounds of iterative error-prone PCR and biopanning, surface topology and structure was essentially maintained using IgE-antibodies from cat allergic patients for phage enrichment. Four candidates were isolated, displaying similar or lower IgE binding, reduced anaphylactic activity as measured by their capacity to induce basophil degranulation and, importantly, a significantly lower T cell reactivity in lymphoproliferative assays compared to the original rFel d 1. In addition, all mutants showed ability to induce blocking antibodies in immunized mice.The approach presented here provides a straightforward procedure to generate a novel type of allergy vaccines for safer and efficacious treatment of allergic patients.

  14. In vitro evolution of allergy vaccine candidates, with maintained structure, but reduced B cell and T cell activation capacity.

    Science.gov (United States)

    Nilsson, Ola B; Adedoyin, Justus; Rhyner, Claudio; Neimert-Andersson, Theresa; Grundström, Jeanette; Berndt, Kurt D; Crameri, Reto; Grönlund, Hans

    2011-01-01

    Allergy and asthma to cat (Felis domesticus) affects about 10% of the population in affluent countries. Immediate allergic symptoms are primarily mediated via IgE antibodies binding to B cell epitopes, whereas late phase inflammatory reactions are mediated via activated T cell recognition of allergen-specific T cell epitopes. Allergen-specific immunotherapy relieves symptoms and is the only treatment inducing a long-lasting protection by induction of protective immune responses. The aim of this study was to produce an allergy vaccine designed with the combined features of attenuated T cell activation, reduced anaphylactic properties, retained molecular integrity and induction of efficient IgE blocking IgG antibodies for safer and efficacious treatment of patients with allergy and asthma to cat. The template gene coding for rFel d 1 was used to introduce random mutations, which was subsequently expressed in large phage libraries. Despite accumulated mutations by up to 7 rounds of iterative error-prone PCR and biopanning, surface topology and structure was essentially maintained using IgE-antibodies from cat allergic patients for phage enrichment. Four candidates were isolated, displaying similar or lower IgE binding, reduced anaphylactic activity as measured by their capacity to induce basophil degranulation and, importantly, a significantly lower T cell reactivity in lymphoproliferative assays compared to the original rFel d 1. In addition, all mutants showed ability to induce blocking antibodies in immunized mice.The approach presented here provides a straightforward procedure to generate a novel type of allergy vaccines for safer and efficacious treatment of allergic patients.

  15. Discovery of Novel Leptospirosis Vaccine Candidates Using Reverse and Structural Vaccinology

    Directory of Open Access Journals (Sweden)

    Alan John Alexander McBride

    2017-04-01

    Full Text Available Leptospira spp. are diderm (two membranes bacteria that infect mammals causing leptospirosis, a public health problem with global implications. Thousands of people die every year due to leptospirosis, especially in developing countries with tropical climates. Prophylaxis is difficult due to multiple factors, including the large number of asymptomatic hosts that transmit the bacteria, poor sanitation, increasing numbers of slum dwellers, and the lack of an effective vaccine. Several leptospiral recombinant antigens were evaluated as a replacement for the inactivated (bacterin vaccine; however, success has been limited. A prospective vaccine candidate is likely to be a surface-related protein that can stimulate the host immune response to clear leptospires from blood and organs. In this study, a comprehensive bioinformatics approach based on reverse and structural vaccinology was applied toward the discovery of novel leptospiral vaccine candidates. The Leptospira interrogans serovar Copenhageni strain L1-130 genome was mined in silico for the enhanced identification of conserved β-barrel (βb transmembrane proteins and outer membrane (OM lipoproteins. Orthologs of the prospective vaccine candidates were screened in the genomes of 20 additional Leptospira spp. Three-dimensional structural models, with a high degree of confidence, were created for each of the surface-exposed proteins. Major histocompatibility complex II (MHC-II epitopes were identified, and their locations were mapped on the structural models. A total of 18 βb transmembrane proteins and 8 OM lipoproteins were identified. These proteins were conserved among the pathogenic Leptospira spp. and were predicted to have epitopes for several variants of MHC-II receptors. A structural and functional analysis of the sequence of these surface proteins demonstrated that most βb transmembrane proteins seem to be TonB-dependent receptors associated with transportation. Other proteins

  16. Dual energy CT with one full scan and a second sparse-view scan using structure preserving iterative reconstruction (SPIR)

    Science.gov (United States)

    Wang, Tonghe; Zhu, Lei

    2016-09-01

    Conventional dual-energy CT (DECT) reconstruction requires two full-size projection datasets with two different energy spectra. In this study, we propose an iterative algorithm to enable a new data acquisition scheme which requires one full scan and a second sparse-view scan for potential reduction in imaging dose and engineering cost of DECT. A bilateral filter is calculated as a similarity matrix from the first full-scan CT image to quantify the similarity between any two pixels, which is assumed unchanged on a second CT image since DECT scans are performed on the same object. The second CT image from reduced projections is reconstructed by an iterative algorithm which updates the image by minimizing the total variation of the difference between the image and its filtered image by the similarity matrix under data fidelity constraint. As the redundant structural information of the two CT images is contained in the similarity matrix for CT reconstruction, we refer to the algorithm as structure preserving iterative reconstruction (SPIR). The proposed method is evaluated on both digital and physical phantoms, and is compared with the filtered-backprojection (FBP) method, the conventional total-variation-regularization-based algorithm (TVR) and prior-image-constrained-compressed-sensing (PICCS). SPIR with a second 10-view scan reduces the image noise STD by a factor of one order of magnitude with same spatial resolution as full-view FBP image. SPIR substantially improves over TVR on the reconstruction accuracy of a 10-view scan by decreasing the reconstruction error from 6.18% to 1.33%, and outperforms TVR at 50 and 20-view scans on spatial resolution with a higher frequency at the modulation transfer function value of 10% by an average factor of 4. Compared with the 20-view scan PICCS result, the SPIR image has 7 times lower noise STD with similar spatial resolution. The electron density map obtained from the SPIR-based DECT images with a second 10-view scan has an

  17. Experimental characterization of the ITER TF structure cooling in HELIOS test facility

    Science.gov (United States)

    Hoa, C.; Rousset, B.; Lacroix, B.; Nicollet, S.; Vallcorba, R.; Bessette, D.; Vostner, A.; Gauthier, F.

    2015-12-01

    During ITER plasma operation, large thermal loads are generated in the stainless steel Toroidal Field (TF) coil casing. To minimize the impact on the temperature of the TF Cable in Conduit Conductor (CICC), these heat loads are intercepted by case cooling channels which are implemented at the interface to the winding pack. One of the design options for the case cooling channels consists of a stainless steel pipe inserted in a rectangular groove which is machined in the casing and filled by a charged resin of high thermal conductivity. A higher number of cooling pipes is arranged at the plasma facing wall of the case, thus providing a better shielding to the TF conductor at high field. To assess the efficiency of the cooling pipes and their thermal coupling with the charged resin, experimental characterizations have been performed. First of all, the thermal resistance vs temperature of some of the individual components of a TF coil has been measured on representative samples in a cryogenic bench. Further characterizations have been performed on an integrated mock-up of the TF cooling scheme at cryogenic temperature in HELIOS test facility at CEA Grenoble. The mock-up consists of a piece of TF casing that can be heated uniformly on its surface, one cooling channel implemented in the groove which is filled with the charged resin, the filler, the ground insulation, the radial plate and one insulated CICC. The cooling pipe and the CICC are cooled by supercritical helium at 4.4 K and 5 bar; the instrumentation consists of temperature, pressure and mass flow sensors. Both stationary and transient operating modes have been investigated to assess the thermal efficiency of the case cooling design. The experimental tests are presented and the first results are discussed and analyzed in this document.

  18. submitter Physical Properties of a High-Strength Austenitic Stainless Steel for the Precompression Structure of the ITER Central Solenoid

    CERN Document Server

    Sgobba, Stefano; Arauzo, Ana; Roussel, Pascal; Libeyre, Paul

    2016-01-01

    The ITER central solenoid (CS) consists of six independent coils kept together by a precompression support structure that must react vertical tensile loads and provide sufficient preload to maintain coil-to-coil contact when the solenoid is energized. The CS precompression system includes tie plates, lower and upper key blocks, load distribution and isolation plates and other attachment, support and insulating hardware. The tie plates operating at 4 K are manufactured starting from forgings in a high-strength austenitic stainless steel (FXM-19) with a stringent specification. Moreover, forged components for the lower and upper key blocks have to be provided in the same FXM-19 grade with comparably strict requirements. FXM-19 is a high-nitrogen austenitic stainless steel, featuring high strength and toughness, ready weldability, and forgeability. It features as well higher integral thermal contraction down to 4 K compared with the very high Mn steel grade selected for the CS coil jackets, hence providing an ad...

  19. Construction of robust dynamic genome-scale metabolic model structures of Saccharomyces cerevisiae through iterative re-parameterization.

    Science.gov (United States)

    Sánchez, Benjamín J; Pérez-Correa, José R; Agosin, Eduardo

    2014-09-01

    Dynamic flux balance analysis (dFBA) has been widely employed in metabolic engineering to predict the effect of genetic modifications and environmental conditions in the cell׳s metabolism during dynamic cultures. However, the importance of the model parameters used in these methodologies has not been properly addressed. Here, we present a novel and simple procedure to identify dFBA parameters that are relevant for model calibration. The procedure uses metaheuristic optimization and pre/post-regression diagnostics, fixing iteratively the model parameters that do not have a significant role. We evaluated this protocol in a Saccharomyces cerevisiae dFBA framework calibrated for aerobic fed-batch and anaerobic batch cultivations. The model structures achieved have only significant, sensitive and uncorrelated parameters and are able to calibrate different experimental data. We show that consumption, suboptimal growth and production rates are more useful for calibrating dynamic S. cerevisiae metabolic models than Boolean gene expression rules, biomass requirements and ATP maintenance.

  20. The candidate cluster and protocluster catalog (CCPC) II: Spectroscopically identified structures spanning 2 < z < 6.6

    CERN Document Server

    Franck, J R

    2016-01-01

    The Candidate Cluster and Protocluster Catalog (CCPC) is a list of objects at redshifts z > 2 composed of galaxies with spectroscopically confirmed redshifts that are coincident on the sky and in redshift. These protoclusters are identified by searching for groups in volumes corresponding to the expected size of the most massive protoclusters at these redshifts. In CCPC1 we identified 43 candidate protoclusters among 14,000 galaxies between 2.74 2.00, resulting in an additional 173 candidate structures. The most significant of these are 36 protoclusters with overdensities {\\delta} > 7. We also identify three large proto-supercluster candidates containing multiple protoclusters at z = 2.3, 3.5 and z = 6.56. Eight candidates with N > 10 or more galaxies are found at redshifts z > 4.0. The last system in the catalog is the most distant spectroscopic protocluster candidate known to date at z = 6.56.

  1. Identification of candidate structured RNAs in the marine organism 'Candidatus Pelagibacter ubique'

    Directory of Open Access Journals (Sweden)

    Schwalbach Michael S

    2009-06-01

    Full Text Available Abstract Background Metagenomic sequence data are proving to be a vast resource for the discovery of biological components. Yet analysis of this data to identify functional RNAs lags behind efforts to characterize protein diversity. The genome of 'Candidatus Pelagibacter ubique' HTCC 1062 is the closest match for approximately 20% of marine metagenomic sequence reads. It is also small, contains little non-coding DNA, and has strikingly low GC content. Results To aid the discovery of RNA motifs within the marine metagenome we exploited the genomic properties of 'Cand. P. ubique' by targeting our search to long intergenic regions (IGRs with relatively high GC content. Analysis of known RNAs (rRNA, tRNA, riboswitches etc. shows that structured RNAs are significantly enriched in such IGRs. To identify additional candidate structured RNAs, we examined other IGRs with similar characteristics from 'Cand. P. ubique' using comparative genomics approaches in conjunction with marine metagenomic data. Employing this strategy, we discovered four candidate structured RNAs including a new riboswitch class as well as three additional likely cis-regulatory elements that precede genes encoding ribosomal proteins S2 and S12, and the cytoplasmic protein component of the signal recognition particle. We also describe four additional potential RNA motifs with few or no examples occurring outside the metagenomic data. Conclusion This work begins the process of identifying functional RNA motifs present in the metagenomic data and illustrates how existing completed genomes may be used to aid in this task.

  2. Theoretical investigations of candidate crystal structures for β-carbonic acid.

    Science.gov (United States)

    Reddy, Sandeep Kumar; Kulkarni, Chidambar H; Balasubramanian, Sundaram

    2011-03-28

    Using multiple computational tools, we examine five candidate crystal structures for β-carbonic acid, a molecular crystal of environmental and astrophysical significance. These crystals comprise of hydrogen bonded molecules in either sheetlike or chainlike topologies. Gas phase quantum calculations, empirical force field based crystal structure search, and periodic density functional theory based calculations and finite temperature simulations of these crystals have been carried out. The infrared spectrum calculated from density functional theory based molecular dynamics simulations compares well with experimental data. Results suggest crystals with one-dimensional hydrogen bonding topologies (chainlike) to be more stable than those with two-dimensional (sheetlike) hydrogen bonding networks. We predict that these structures can be distinguished on the basis of their far infrared spectra.

  3. Rapid discovery of peptide capture candidates with demonstrated specificity for structurally similar toxins

    Science.gov (United States)

    Sarkes, Deborah A.; Hurley, Margaret M.; Coppock, Matthew B.; Farrell, Mikella E.; Pellegrino, Paul M.; Stratis-Cullum, Dimitra N.

    2016-05-01

    Peptides have emerged as viable alternatives to antibodies for molecular-based sensing due to their similarity in recognition ability despite their relative structural simplicity. Various methods for peptide capture reagent discovery exist, including phage display, yeast display, and bacterial display. One of the primary advantages of peptide discovery by bacterial display technology is the speed to candidate peptide capture agent, due to both rapid growth of bacteria and direct utilization of the sorted cells displaying each individual peptide for the subsequent round of biopanning. We have previously isolated peptide affinity reagents towards protective antigen of Bacillus anthracis using a commercially available automated magnetic sorting platform with improved enrichment as compared to manual magnetic sorting. In this work, we focus on adapting our automated biopanning method to a more challenging sort, to demonstrate the specificity possible with peptide capture agents. This was achieved using non-toxic, recombinant variants of ricin and abrin, RiVax and abrax, respectively, which are structurally similar Type II ribosomal inactivating proteins with significant sequence homology. After only two rounds of biopanning, enrichment of peptide capture candidates binding abrax but not RiVax was achieved as demonstrated by Fluorescence Activated Cell Sorting (FACS) studies. Further sorting optimization included negative sorting against RiVax, proper selection of autoMACS programs for specific sorting rounds, and using freshly made buffer and freshly thawed protein target for each round of biopanning for continued enrichment over all four rounds. Most of the resulting candidates from biopanning for abrax binding peptides were able to bind abrax but not RiVax, demonstrating that short peptide sequences can be highly specific even at this early discovery stage.

  4. A preliminary design and structural analysis of the lifting tools for 40° sector sub-assembly and handling ITER components

    Energy Technology Data Exchange (ETDEWEB)

    Nam, Kyoungo, E-mail: namko@nfri.re.kr [ITER Korea, Gwahangno 113, Yuseong-gu, Daejeon 305-333 (Korea, Republic of); Park, Hyunki; Im, Kihak; Kim, Dongjin; Ahn, Heejae [ITER Korea, Gwahangno 113, Yuseong-gu, Daejeon 305-333 (Korea, Republic of); Lee, Jaehyuk; Moon, Jaewhan [SFA Inc., 166 Sinhang-ri, Dunpo-myeon, Asan-si, Chungcheongnam-do 336-873 (Korea, Republic of); Watson, Emma; Shaw, Robert [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France)

    2013-10-15

    The purpose-built, ITER tokamak assembly tools, which are to be provided by Korea, should be designed to meet: the assembly plan, space reservations, safety standards, simple operations, efficient maintenance, and so on. It is very important that the ITER assembly tools are able to lift and transfer ITER components or their sub-assemblies to their assembled position safely. Furthermore, the lifting tools will lift and handle very heavy loads that can be more than 1200 tonnes sometimes. Therefore, the ITER lifting tools must be designed to endure these heavy load conditions with regard to their structural integrity. Also, these designs should be verified through an appropriate method. The preliminary design of the sector lifting tool and associated lifting attachments are introduced in this paper. The sector lifting tool was designed especially to lift and handle various ITER components by adjusting the lifting centre. The structural analysis results using ANSYS are described considering the heaviest load condition. The results of the analysis show that; all stresses applied on the lifting tool are lower than the allowable stress of the applied material.

  5. Genetic diversity and population structure of genes encoding vaccine candidate antigens of Plasmodium vivax

    Directory of Open Access Journals (Sweden)

    Chenet Stella M

    2012-03-01

    Full Text Available Abstract Background A major concern in malaria vaccine development is genetic polymorphisms typically observed among Plasmodium isolates in different geographical areas across the world. Highly polymorphic regions have been observed in Plasmodium falciparum and Plasmodium vivax antigenic surface proteins such as Circumsporozoite protein (CSP, Duffy-binding protein (DBP, Merozoite surface protein-1 (MSP-1, Apical membrane antigen-1 (AMA-1 and Thrombospondin related anonymous protein (TRAP. Methods Genetic variability was assessed in important polymorphic regions of various vaccine candidate antigens in P. vivax among 106 isolates from the Amazon Region of Loreto, Peru. In addition, genetic diversity determined in Peruvian isolates was compared to population studies from various geographical locations worldwide. Results The structured diversity found in P. vivax populations did not show a geographic pattern and haplotypes from all gene candidates were distributed worldwide. In addition, evidence of balancing selection was found in polymorphic regions of the trap, dbp and ama-1 genes. Conclusions It is important to have a good representation of the haplotypes circulating worldwide when implementing a vaccine, regardless of the geographic region of deployment since selective pressure plays an important role in structuring antigen diversity.

  6. Study of large and highly stratified population datasets by combining iterative pruning principal component analysis and structure

    Directory of Open Access Journals (Sweden)

    Piriyapongsa Jittima

    2011-06-01

    Full Text Available Abstract Background The ever increasing sizes of population genetic datasets pose great challenges for population structure analysis. The Tracy-Widom (TW statistical test is widely used for detecting structure. However, it has not been adequately investigated whether the TW statistic is susceptible to type I error, especially in large, complex datasets. Non-parametric, Principal Component Analysis (PCA based methods for resolving structure have been developed which rely on the TW test. Although PCA-based methods can resolve structure, they cannot infer ancestry. Model-based methods are still needed for ancestry analysis, but they are not suitable for large datasets. We propose a new structure analysis framework for large datasets. This includes a new heuristic for detecting structure and incorporation of the structure patterns inferred by a PCA method to complement STRUCTURE analysis. Results A new heuristic called EigenDev for detecting population structure is presented. When tested on simulated data, this heuristic is robust to sample size. In contrast, the TW statistic was found to be susceptible to type I error, especially for large population samples. EigenDev is thus better-suited for analysis of large datasets containing many individuals, in which spurious patterns are likely to exist and could be incorrectly interpreted as population stratification. EigenDev was applied to the iterative pruning PCA (ipPCA method, which resolves the underlying subpopulations. This subpopulation information was used to supervise STRUCTURE analysis to infer patterns of ancestry at an unprecedented level of resolution. To validate the new approach, a bovine and a large human genetic dataset (3945 individuals were analyzed. We found new ancestry patterns consistent with the subpopulations resolved by ipPCA. Conclusions The EigenDev heuristic is robust to sampling and is thus superior for detecting structure in large datasets. The application of EigenDev to

  7. Electronic structure of Ta2NiSe5 as a candidate for excitonic insulators

    Science.gov (United States)

    Kaneko, T.; Toriyama, T.; Konishi, T.; Ohta, Y.

    2012-12-01

    We make the electronic structure calculations of Ta2NiSe5 known as a candidate for excitonic insulators where the semiconducting or semi-metallic ground state becomes unstable against the coherent formation of excitons. We use the generalized gradient approximation (GGA) in the density functional theory, where the Hubbard-type repulsive interaction U is taken into account (GGA+U). We find that the material has a very simple quasi-one-dimensional (1D) electronic structure which relates to the formation of excitons. From the calculated partial density of states, band dispersion and spatial distribution of charge densities, we find in the first approximation that the conduction band is configured by the Ta 1D chain and the valence band is configured by the Ni-Se 1D chain.

  8. Structural identifiability analyses of candidate models for in vitro Pitavastatin hepatic uptake.

    Science.gov (United States)

    Grandjean, Thomas R B; Chappell, Michael J; Yates, James W T; Evans, Neil D

    2014-05-01

    In this paper a review of the application of four different techniques (a version of the similarity transformation approach for autonomous uncontrolled systems, a non-differential input/output observable normal form approach, the characteristic set differential algebra and a recent algebraic input/output relationship approach) to determine the structural identifiability of certain in vitro nonlinear pharmacokinetic models is provided. The Organic Anion Transporting Polypeptide (OATP) substrate, Pitavastatin, is used as a probe on freshly isolated animal and human hepatocytes. Candidate pharmacokinetic non-linear compartmental models have been derived to characterise the uptake process of Pitavastatin. As a prerequisite to parameter estimation, structural identifiability analyses are performed to establish that all unknown parameters can be identified from the experimental observations available.

  9. Sequence Memory Constraints Give Rise to Language-Like Structure through Iterated Learning.

    Science.gov (United States)

    Cornish, Hannah; Dale, Rick; Kirby, Simon; Christiansen, Morten H

    2017-01-01

    Human language is composed of sequences of reusable elements. The origins of the sequential structure of language is a hotly debated topic in evolutionary linguistics. In this paper, we show that sets of sequences with language-like statistical properties can emerge from a process of cultural evolution under pressure from chunk-based memory constraints. We employ a novel experimental task that is non-linguistic and non-communicative in nature, in which participants are trained on and later asked to recall a set of sequences one-by-one. Recalled sequences from one participant become training data for the next participant. In this way, we simulate cultural evolution in the laboratory. Our results show a cumulative increase in structure, and by comparing this structure to data from existing linguistic corpora, we demonstrate a close parallel between the sets of sequences that emerge in our experiment and those seen in natural language.

  10. Sequence Memory Constraints Give Rise to Language-Like Structure through Iterated Learning

    Science.gov (United States)

    Cornish, Hannah; Dale, Rick; Kirby, Simon; Christiansen, Morten H.

    2017-01-01

    Human language is composed of sequences of reusable elements. The origins of the sequential structure of language is a hotly debated topic in evolutionary linguistics. In this paper, we show that sets of sequences with language-like statistical properties can emerge from a process of cultural evolution under pressure from chunk-based memory constraints. We employ a novel experimental task that is non-linguistic and non-communicative in nature, in which participants are trained on and later asked to recall a set of sequences one-by-one. Recalled sequences from one participant become training data for the next participant. In this way, we simulate cultural evolution in the laboratory. Our results show a cumulative increase in structure, and by comparing this structure to data from existing linguistic corpora, we demonstrate a close parallel between the sets of sequences that emerge in our experiment and those seen in natural language. PMID:28118370

  11. Improving search for low energy protein structures with an iterative niche genetic algorithm

    DEFF Research Database (Denmark)

    Helles, Glennie

    2010-01-01

    In attempts to predict the tertiary structure of proteins we use almost exclusively metaheuristics. However, despite known differences in performance of metaheuristics for different problems, the effect of the choice of metaheuristic has received precious little attention in this field. Particula...

  12. Combining Evolutionary Information and an Iterative Sampling Strategy for Accurate Protein Structure Prediction.

    Directory of Open Access Journals (Sweden)

    Tatjana Braun

    2015-12-01

    Full Text Available Recent work has shown that the accuracy of ab initio structure prediction can be significantly improved by integrating evolutionary information in form of intra-protein residue-residue contacts. Following this seminal result, much effort is put into the improvement of contact predictions. However, there is also a substantial need to develop structure prediction protocols tailored to the type of restraints gained by contact predictions. Here, we present a structure prediction protocol that combines evolutionary information with the resolution-adapted structural recombination approach of Rosetta, called RASREC. Compared to the classic Rosetta ab initio protocol, RASREC achieves improved sampling, better convergence and higher robustness against incorrect distance restraints, making it the ideal sampling strategy for the stated problem. To demonstrate the accuracy of our protocol, we tested the approach on a diverse set of 28 globular proteins. Our method is able to converge for 26 out of the 28 targets and improves the average TM-score of the entire benchmark set from 0.55 to 0.72 when compared to the top ranked models obtained by the EVFold web server using identical contact predictions. Using a smaller benchmark, we furthermore show that the prediction accuracy of our method is only slightly reduced when the contact prediction accuracy is comparatively low. This observation is of special interest for protein sequences that only have a limited number of homologs.

  13. New concurrent iterative methods with monotonic convergence

    Energy Technology Data Exchange (ETDEWEB)

    Yao, Qingchuan [Michigan State Univ., East Lansing, MI (United States)

    1996-12-31

    This paper proposes the new concurrent iterative methods without using any derivatives for finding all zeros of polynomials simultaneously. The new methods are of monotonic convergence for both simple and multiple real-zeros of polynomials and are quadratically convergent. The corresponding accelerated concurrent iterative methods are obtained too. The new methods are good candidates for the application in solving symmetric eigenproblems.

  14. Explosive welding method for manufacturing ITER-grade 316L(N)/CuCrZr hollow structural member

    Energy Technology Data Exchange (ETDEWEB)

    Ma, Rui, E-mail: mr9980@163.com [PLA University of Science and Technology, Nanjing 210007 (China); Wang, Yaohua [PLA University of Science and Technology, Nanjing 210007 (China); Wu, Jihong [Southwestern Institute of Physics, Chengdu 610041 (China); Duan, Mianjun [PLA University of Science and Technology, Nanjing 210007 (China)

    2014-12-15

    Highlights: • Develop a new explosive welding method to fabricate the cooling channel of FW. • Utilize effective energy model to accurately calculate optimal welding parameters. • Provide an efficient way for manufacturing high-ductility hollow structural member. - Abstract: In this study, a new explosive welding method provided an effective way for manufacturing ITER-grade 316L(N)/CuCrZr hollow structural member. The welding parameters (stand-off distance and explosion rate) were calculated respectively using equivalent frontal collision wave model and effective energy model. The welded samples were subject to two step heat treatment cycles (solution annealing and aging). Optical microscopy (OM) and scanning electron microscopy (SEM) were utilized to analyze the microstructure of bonding interface. The mechanical properties of the welded samples were evaluated through microhardness test and tensile test. Moreover, the sealing property of the welded specimens was measured through helium leak test. Microstructural analysis showed that the welded sample using effective energy model had an ideal wavy interface. The results of microhardness test revealed an increase in hardness for both sides near to the bonding interface. And the hardening phenomenon of interface region disappeared after the solution annealing. SEM observation indicated that the samples with the post heat treatments exhibited a ductile fracture with dimple features after tensile test. After the specimens undergo aging strengthening, there was an obvious increase in the strength for all specimens. The helium leak test results have proven that the welded specimens are soundness.

  15. Quantum Iterated Function Systems

    CERN Document Server

    Lozinski, A; Slomczynski, W; Lozinski, Artur; Zyczkowski, Karol; Slomczynski, Wojciech

    2003-01-01

    Iterated functions system (IFS) is defined by specifying a set of functions in a classical phase space, which act randomly on the initial point. In an analogous way, we define quantum iterated functions system (QIFS), where functions act randomly with prescribed probabilities in the Hilbert space. In a more general setting a QIFS consists of completely positive maps acting in the space of density operators. We present exemplary classical IFSs, the invariant measure of which exhibits fractal structure, and study properties of the corresponding QIFSs and their invariant state.

  16. Mechanical properties data of candidate alloys for earth penetrator structural components

    Energy Technology Data Exchange (ETDEWEB)

    Van Den Avyle, J A

    1978-04-01

    Loading modes imposed on earth penetrators during impact and subsurface travel include high rate axial compressive stresses and possibly large tensile bending stresses caused by off-axis impacts or collisions with hard sub-surface objects. These modes require that case structural alloys possess a high yield strength to prevent yielding under compressive loads and also possess high fracture toughness to resist fracture under tensile loading at stress concentrations. Tensile data were generated at intermediate strain rates (epsilon less than 300 sec/sup -1/) between 219 and 344/sup 0/K for four candidate steels (9-4-20, maraging 250, HY-180, and D6AC). In general, yield strengths varied less than 10 percent over the ranges of strain rate and temperature tested. Charpy impact energy measurements on 9-4-20 showed a 10 percent decrease in toughness at low temperatures for samples subjected to a simulated heat-shrink fitting procedure. Additional fracture toughness tests (K/sub IC/) were conducted on 9-4-20 with varied tempering treatments and on two forged billets of HY-180. Strength and toughness data for several candidate alloys gathered from the literature are presented, and recommendations are made for trade-offs in strength versus toughness.

  17. Evidence of novel fine-scale structural variation at autism spectrum disorder candidate loci

    Directory of Open Access Journals (Sweden)

    Hedges Dale J

    2012-04-01

    Full Text Available Abstract Background Autism spectrum disorders (ASD represent a group of neurodevelopmental disorders characterized by a core set of social-communicative and behavioral impairments. Gamma-aminobutyric acid (GABA is the major inhibitory neurotransmitter in the brain, acting primarily via the GABA receptors (GABR. Multiple lines of evidence, including altered GABA and GABA receptor expression in autistic patients, indicate that the GABAergic system may be involved in the etiology of autism. Methods As copy number variations (CNVs, particularly rare and de novo CNVs, have now been implicated in ASD risk, we examined the GABA receptors and genes in related pathways for structural variation that may be associated with autism. We further extended our candidate gene set to include 19 genes and regions that had either been directly implicated in the autism literature or were directly related (via function or ancestry to these primary candidates. For the high resolution CNV screen we employed custom-designed 244 k comparative genomic hybridization (CGH arrays. Collectively, our probes spanned a total of 11 Mb of GABA-related and additional candidate regions with a density of approximately one probe every 200 nucleotides, allowing a theoretical resolution for detection of CNVs of approximately 1 kb or greater on average. One hundred and sixty-eight autism cases and 149 control individuals were screened for structural variants. Prioritized CNV events were confirmed using quantitative PCR, and confirmed loci were evaluated on an additional set of 170 cases and 170 control individuals that were not included in the original discovery set. Loci that remained interesting were subsequently screened via quantitative PCR on an additional set of 755 cases and 1,809 unaffected family members. Results Results include rare deletions in autistic individuals at JAKMIP1, NRXN1, Neuroligin4Y, OXTR, and ABAT. Common insertion/deletion polymorphisms were detected at several

  18. Iterative solution of multiple radiation and scattering problems in structural acoustics using the BL-QMR algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Malhotra, M. [Stanford Univ., CA (United States)

    1996-12-31

    Finite-element discretizations of time-harmonic acoustic wave problems in exterior domains result in large sparse systems of linear equations with complex symmetric coefficient matrices. In many situations, these matrix problems need to be solved repeatedly for different right-hand sides, but with the same coefficient matrix. For instance, multiple right-hand sides arise in radiation problems due to multiple load cases, and also in scattering problems when multiple angles of incidence of an incoming plane wave need to be considered. In this talk, we discuss the iterative solution of multiple linear systems arising in radiation and scattering problems in structural acoustics by means of a complex symmetric variant of the BL-QMR method. First, we summarize the governing partial differential equations for time-harmonic structural acoustics, the finite-element discretization of these equations, and the resulting complex symmetric matrix problem. Next, we sketch the special version of BL-QMR method that exploits complex symmetry, and we describe the preconditioners we have used in conjunction with BL-QMR. Finally, we report some typical results of our extensive numerical tests to illustrate the typical convergence behavior of BL-QMR method for multiple radiation and scattering problems in structural acoustics, to identify appropriate preconditioners for these problems, and to demonstrate the importance of deflation in block Krylov-subspace methods. Our numerical results show that the multiple systems arising in structural acoustics can be solved very efficiently with the preconditioned BL-QMR method. In fact, for multiple systems with up to 40 and more different right-hand sides we get consistent and significant speed-ups over solving the systems individually.

  19. Structural model for the first wall W-based material in ITER project

    Institute of Scientific and Technical Information of China (English)

    Dehua Xu; Xinkui He; Shuiquan Deng; Yong Zhao

    2014-01-01

    The preparation, characterization, and test of the first wall materials designed to be used in the fusion reactor have remained challenging problems in the material science. This work uses the first-principles method as implemented in the CASTEP package to study the influ-ences of the doped titanium carbide on the structural sta-bility of the W–TiC material. The calculated total energy and enthalpy have been used as criteria to judge the structural models built with consideration of symmetry. Our simulation indicates that the doped TiC tends to form its own domain up to the investigated nano-scale, which implies a possible phase separation. This result reveals the intrinsic reason for the composite nature of the W–TiC material and provides an explanation for the experimen-tally observed phase separation at the nano-scale. Our approach also sheds a light on explaining the enhancing effects of doped components on the durability, reliability, corrosion resistance, etc., in many special steels.

  20. Vertical stability of ITER plasmas with 3D passive structures and a double-loop control system

    Energy Technology Data Exchange (ETDEWEB)

    Portone, A. [EFDA-CSU, Max Planck Institute for Plasmaphysics, Boltzmannstrasse 2, D-85748 Garching (Germany)]. E-mail: alfredo.portone@tech.efda.org; Albanese, R. [Assoc. Euratom-ENEA-CREATE, University Mediterranea RC, Loc. Feo di Vito, I-89060, RC (Italy); Fresa, R. [DIFA, University della Bastilicata, Contrada Macchia Romana I-85100, Potenza (Italy); Mattei, M. [Assoc. Euratom-ENEA-CREATE, University Mediterranea RC, Loc. Feo di Vito, I-89060, RC (Italy); Rubinacci, G. [Assoc. Euratom-ENEA-CREATE, University Cassino, Via Di Biasio 43, I-03043, Cassino (FR) (Italy); Villone, F. [Assoc. Euratom-ENEA-CREATE, University Cassino, Via Di Biasio 43, I-03043, Cassino (FR) (Italy)

    2005-11-15

    In this study we derive linear models describing the dynamics of the n 0 plasma displacements around the main ITER equilibrium configurations. The models derived are consistent with the MHD equilibrium constraint as well as with the 3D geometry of the vacuum vessel and blanket outer triangular support where the main eddy currents flow takes place. Particular emphasis is placed on the analysis of the stability margin, growth time and minimum stabilization voltage. The performances of the present ITER control system (single loop) are compared to those of an upgraded system (double-loop) that is here proposed to improve the stability domain of the ITER plasmas forecast.

  1. Mechanical properties of full austenitic welding joint at cryogenic temperature for the ITER toroidal field coil structure

    Energy Technology Data Exchange (ETDEWEB)

    Iguchi, M., E-mail: iguchi.masahide@jaea.go.jp [Japan Atomic Energy Agency, ITER Superconducting Magnet Technology Group, 801-1 Mukoyama, Naka, Ibaraki 311-0193 Japan (Japan); Saito, T.; Kawano, K.; Chida, Y.; Nakajima, H. [Japan Atomic Energy Agency, ITER Superconducting Magnet Technology Group, 801-1 Mukoyama, Naka, Ibaraki 311-0193 Japan (Japan); Ogawa, T.; Katayama, Y.; Ogata, H.; Minemura, T. [Toshiba Cooperation, Power Systems Company, 2-4, Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 2300-0045 (Japan); Tokai, D.; Niimi, K. [Kawasaki Heavy Industries, LTD., Plant and Infrastructure Company, Production Center, 8, Niijima, Harima-cho, Kako-gun, Hyogo 675-0180 (Japan)

    2013-10-15

    Highlights: • No significant distribution of tensile strengths at 4 K, 77 K and room temperature along welding thickness of 200 mm manufactured by one side narrow gap TIG welding with FMYJJ1. • Tensile strengths at cryogenic temperature of welded joint are increased with increasing of C + N contents of base material. • In the case that welded joint is manufactured by combination of different base materials, strength at 4 K of welded joints are below strength of base material having higher C + N contents. -- Abstract: ITER toroidal field coil (TFC) structures are large welding structures composed of coil case and support structures made of heavy thick high strength and high toughness stainless steels. Japan Atomic Energy Agency plans to apply narrow gap Tungsten Inert Gas (TIG) welding with FMYJJ1 (0.03C–10Mn–12Cr–14Ni–5Mo–0.13N) which is full austenitic stainless filler material. In order to evaluate effect of base material thickness and combinations of base material on tensile properties, tensile tests were performed at room temperature, 77 K and 4 K by using tensile specimens taken from 200 mm thickness welded joints of two combinations of base materials and 40 mm thickness welded joints of four combinations of base materials. As the results, it was confirmed that there were no large distribution of yield and tensile strength along the thickness of welded joints of 200 mm thickness and yield and tensile strengths of welded joints were decreased with decreasing of C + N contents of base material.

  2. Space-filling curves of self-similar sets (I): iterated function systems with order structures

    Science.gov (United States)

    Rao, Hui; Zhang, Shu-Qin

    2016-07-01

    This paper is the first part of a series which provides a systematic treatment of the space-filling curves of self-similar sets. In the present paper, we introduce a notion of linear graph-directed IFS (linear GIFS in short). We show that to construct a space-filling curve of a self-similar set, it amounts to exploring its linear GIFS structures. Compared to the previous methods, such as the L-system or recurrent set method, the linear GIFS approach is simpler, more rigorous and leads to further studies on this topic. We also propose a new algorithm for the beautiful visualization of space-filling curves. In a series of papers Dai et al (2015 arXiv:1511.05411 [math.GN]), Rao and Zhang (2015) and Rao and Zhang (2015), we investigate for a given self-similar set how to get ‘substitution rules’ for constructing space-filling curves, which was obscure in the literature. We solve the problem for self-similar sets of finite type, which covers most of the known results on constructions of space-filling curves.

  3. Physics Structure Analysis of Parallel Waves Concept of Physics Teacher Candidate

    Science.gov (United States)

    Sarwi, S.; Supardi, K. I.; Linuwih, S.

    2017-04-01

    The aim of this research was to find a parallel structure concept of wave physics and the factors that influence on the formation of parallel conceptions of physics teacher candidates. The method used qualitative research which types of cross-sectional design. These subjects were five of the third semester of basic physics and six of the fifth semester of wave course students. Data collection techniques used think aloud and written tests. Quantitative data were analysed with descriptive technique-percentage. The data analysis technique for belief and be aware of answers uses an explanatory analysis. Results of the research include: 1) the structure of the concept can be displayed through the illustration of a map containing the theoretical core, supplements the theory and phenomena that occur daily; 2) the trend of parallel conception of wave physics have been identified on the stationary waves, resonance of the sound and the propagation of transverse electromagnetic waves; 3) the influence on the parallel conception that reading textbooks less comprehensive and knowledge is partial understanding as forming the structure of the theory.

  4. Thermo-structural optimization of the ITER ICRH Four Port Junction and Straps against in-vessel design criteria

    Energy Technology Data Exchange (ETDEWEB)

    Lafuente, Antonio, E-mail: anlafuente@gmail.com; Fursdon, Mike; Shannon, Mark

    2014-10-15

    Design optimization work has been conducted on the ITER Ion Cyclotron Resonance Heating (ICRH) Four Port Junction (4PJ) and Straps – a sub-assembly of the antenna. The aim of the analysis is to evaluate ways of making the component compliant with SDC-IC rules while balancing the competing demands of different performance requirements. Of particular interest are the bends that connect the 316L(N) strap pipes to its housing, where previous work had shown that primary plus secondary stresses would result in a low predicted fatigue life. The aim of the study was to explore the possibility of reducing stresses in these bends. Coupled ANSYS CFX and structural models are used to calculate coolant and metal temperatures and resulting stresses due to incident and self-generated heat. Although all of the modifications explored resulted in primary plus secondary stresses exceeding the cyclic damage design criteria, some avenues are identified for future studies and a reduction in stress toward the target is obtained.

  5. Down the primrose path of dalliance: how iterative structural determination routines for thin films may lead to partial or false solutions

    Science.gov (United States)

    Husseini, Naji; Cionca, Codrin; Yacoby, Yizhak; Clarke, Roy

    2008-03-01

    Iterative methods are frequently used to solve thin film structures. Convergence, however, may terminate at partial or even incorrect solutions. Coherent Bragg Rod Analysis (COBRA), a direct phase retrieval method with minimal iterations, has had recent success with buried interfaces in perovskite oxides and semiconductors. Here, we investigate the role of iterations in COBRA by means of simulations on a model lattice-matched system of PbTiO3 on SrTiO3 with realistic stochastic noise. Out-of-plane atomic displacements were added in various monolayers of the PbTiO3 film. With increasing iterations, the positions of the heaviest element (Pb) became more accurate at the expense of the lighter elements -- particularly the oxygen sublattices. In addition, the error in the central monolayers of the film decreased while the error at both the film-substrate and film-air interface increased. Our results provide new insights on the influence of uncertainties in measuring subtle structural details at interfaces.

  6. Structure of SALO, a leishmaniasis vaccine candidate from the sand fly Lutzomyia longipalpis.

    Science.gov (United States)

    Asojo, Oluwatoyin A; Kelleher, Alan; Liu, Zhuyun; Pollet, Jeroen; Hudspeth, Elissa M; Rezende, Wanderson C; Groen, Mallory Jo; Seid, Christopher A; Abdeladhim, Maha; Townsend, Shannon; de Castro, Waldione; Mendes-Sousa, Antonio; Bartholomeu, Daniella Castanheira; Fujiwara, Ricardo Toshio; Bottazzi, Maria Elena; Hotez, Peter J; Zhan, Bin; Oliveira, Fabiano; Kamhawi, Shaden; Valenzuela, Jesus G

    2017-03-01

    Immunity to the sand fly salivary protein SALO (Salivary Anticomplement of Lutzomyia longipalpis) protected hamsters against Leishmania infantum and L. braziliensis infection and, more recently, a vaccine combination of a genetically modified Leishmania with SALO conferred strong protection against L. donovani infection. Because of the importance of SALO as a potential component of a leishmaniasis vaccine, a plan to produce this recombinant protein for future scale manufacturing as well as knowledge of its structural characteristics are needed to move SALO forward for the clinical path. Recombinant SALO was expressed as a soluble secreted protein using Pichia pastoris, rSALO(P), with yields of 1g/L and >99% purity as assessed by SEC-MALS and SDS-PAGE. Unlike its native counterpart, rSALO(P) does not inhibit the classical pathway of complement; however, antibodies to rSALO(P) inhibit the anti-complement activity of sand fly salivary gland homogenate. Immunization with rSALO(P) produces a delayed type hypersensitivity response in C57BL/6 mice, suggesting rSALO(P) lacked anti-complement activity but retained its immunogenicity. The structure of rSALO(P) was solved by S-SAD at Cu-Kalpha to 1.94 Å and refined to Rfactor 17%. SALO is ~80% helical, has no appreciable structural similarities to any human protein, and has limited structural similarity in the C-terminus to members of insect odorant binding proteins. SALO has three predicted human CD4+ T cell epitopes on surface exposed helices. The results indicate that SALO as expressed and purified from P. pastoris is suitable for further scale-up, manufacturing, and testing. SALO has a novel structure, is not similar to any human proteins, is immunogenic in rodents, and does not have the anti-complement activity observed in the native salivary protein which are all important attributes to move this vaccine candidate forward to the clinical path.

  7. Structure of SALO, a leishmaniasis vaccine candidate from the sand fly Lutzomyia longipalpis.

    Directory of Open Access Journals (Sweden)

    Oluwatoyin A Asojo

    2017-03-01

    Full Text Available Immunity to the sand fly salivary protein SALO (Salivary Anticomplement of Lutzomyia longipalpis protected hamsters against Leishmania infantum and L. braziliensis infection and, more recently, a vaccine combination of a genetically modified Leishmania with SALO conferred strong protection against L. donovani infection. Because of the importance of SALO as a potential component of a leishmaniasis vaccine, a plan to produce this recombinant protein for future scale manufacturing as well as knowledge of its structural characteristics are needed to move SALO forward for the clinical path.Recombinant SALO was expressed as a soluble secreted protein using Pichia pastoris, rSALO(P, with yields of 1g/L and >99% purity as assessed by SEC-MALS and SDS-PAGE. Unlike its native counterpart, rSALO(P does not inhibit the classical pathway of complement; however, antibodies to rSALO(P inhibit the anti-complement activity of sand fly salivary gland homogenate. Immunization with rSALO(P produces a delayed type hypersensitivity response in C57BL/6 mice, suggesting rSALO(P lacked anti-complement activity but retained its immunogenicity. The structure of rSALO(P was solved by S-SAD at Cu-Kalpha to 1.94 Å and refined to Rfactor 17%. SALO is ~80% helical, has no appreciable structural similarities to any human protein, and has limited structural similarity in the C-terminus to members of insect odorant binding proteins. SALO has three predicted human CD4+ T cell epitopes on surface exposed helices.The results indicate that SALO as expressed and purified from P. pastoris is suitable for further scale-up, manufacturing, and testing. SALO has a novel structure, is not similar to any human proteins, is immunogenic in rodents, and does not have the anti-complement activity observed in the native salivary protein which are all important attributes to move this vaccine candidate forward to the clinical path.

  8. Structural damages prevention of the ITER vacuum vessel and ports by elasto-plastic analysis with regards to RCC-MR

    Energy Technology Data Exchange (ETDEWEB)

    Martinez, Jean-Marc, E-mail: jean-marc.martinez@iter.org [ITER Organization, Route de Vinon-sur-Verdon, CS 90 046, 13067 St. Paul Lez Durance Cedex (France); Jun, Chang Hoon; Portafaix, Christophe; Alekseev, Alexander; Sborchia, Carlo; Choi, Chang-Ho [ITER Organization, Route de Vinon-sur-Verdon, CS 90 046, 13067 St. Paul Lez Durance Cedex (France); Albin, Vincent [SOM Calcul – Groupe ORTEC, 121 ancien Chemin de Cassis – Immeuble Grand Pré, 13009 Marseille (France); Borrelly, Stephane [Sogeti High Tech, RE2, 180 rue René Descartes, Le Millenium – Bat C, 13857 Aix en Provence (France); Cambazar, Magali [Assystem EOS, 117 rue Jacquard, 84120 Pertuis (France); Gaucher, Thomas [SOM Calcul – Groupe ORTEC, 121 ancien Chemin de Cassis – Immeuble Grand Pré, 13009 Marseille (France); Sfarni, Samir; Tailhardat, Olivier [Assystem EOS, 117 rue Jacquard, 84120 Pertuis (France)

    2015-10-15

    Highlights: • ITER vacuum vessel (VV) is a part of the first barrier to confine the plasma. • ITER VV as NPE necessitates a third party organization authorized by the French nuclear regulator to assure design, fabrication, and conformance testing and quality assurance, i.e. ANB. • Several types of damages have to be prevented in order to guarantee the structural integrity with regards to RCC-MR. • It is usual to employ non-linear analysis when the “classical” elastic analysis reaches its limit of linear application. • Several structural analyses were performed with many different global and local models of the whole ITER VV. - Abstract: Several types of damages have to be prevented in order to guarantee the structural integrity of a structure with regards to RCC-MR; the P-type damages which can result from the application to a structure of a steadily and regularly increasing loading or a constant loading and the S-type damages during operational loading conditions which can only result from repeated application of loadings associated to the progressive deformations and fatigue. Following RCC-MR, the S-type damages prevention has to be started only when the structural integrity is guaranteed against P-type damages. The verification of the last one on the ITER vacuum vessel and ports has been performed by limit analysis with elasto-(perfectly)plastic material behavior. It is usual to employ non-linear analysis when the “classical” elastic analysis reaches its limit of linear application. Some elasto-plastic analyses have been performed considering several cyclic loadings to evaluate also more realistic structural margins of the against S-type damages.

  9. Systematic structural characterization of metabolites in Arabidopsis via candidate substrate-product pair networks.

    Science.gov (United States)

    Morreel, Kris; Saeys, Yvan; Dima, Oana; Lu, Fachuang; Van de Peer, Yves; Vanholme, Ruben; Ralph, John; Vanholme, Bartel; Boerjan, Wout

    2014-03-01

    Plant metabolomics is increasingly used for pathway discovery and to elucidate gene function. However, the main bottleneck is the identification of the detected compounds. This is more pronounced for secondary metabolites as many of their pathways are still underexplored. Here, an algorithm is presented in which liquid chromatography-mass spectrometry profiles are searched for pairs of peaks that have mass and retention time differences corresponding with those of substrates and products from well-known enzymatic reactions. Concatenating the latter peak pairs, called candidate substrate-product pairs (CSPP), into a network displays tentative (bio)synthetic routes. Starting from known peaks, propagating the network along these routes allows the characterization of adjacent peaks leading to their structure prediction. As a proof-of-principle, this high-throughput cheminformatics procedure was applied to the Arabidopsis thaliana leaf metabolome where it allowed the characterization of the structures of 60% of the profiled compounds. Moreover, based on searches in the Chemical Abstract Service database, the algorithm led to the characterization of 61 compounds that had never been described in plants before. The CSPP-based annotation was confirmed by independent MS(n) experiments. In addition to being high throughput, this method allows the annotation of low-abundance compounds that are otherwise not amenable to isolation and purification. This method will greatly advance the value of metabolomics in systems biology.

  10. On One-Point Iterations and DIIS

    DEFF Research Database (Denmark)

    Østerby, Ole; Sørensen, Hans Henrik Brandenborg

    2009-01-01

    We analyze various iteration procedures in many dimensions inspired by the SCF iteration used in first principles electronic structure calculations. We show that the simple mixing of densities can turn a divergent (or slowly convergent) iteration into a (faster) convergent process provided all th...

  11. Structural characterization of the mechanosensitive channel candidate MCA2 from Arabidopsis thaliana.

    Directory of Open Access Journals (Sweden)

    Hideki Shigematsu

    Full Text Available Mechanosensing in plants is thought to be governed by sensory complexes containing a Ca²⁺-permeable, mechanosensitive channel. The plasma membrane protein MCA1 and its paralog MCA2 from Arabidopsis thaliana are involved in mechanical stress-induced Ca²⁺ influx and are thus considered as candidates for such channels or their regulators. Both MCA1 and MCA2 were functionally expressed in Sf9 cells using a baculovirus system in order to elucidate their molecular natures. Because of the abundance of protein in these cells, MCA2 was chosen for purification. Purified MCA2 in a detergent-solubilized state formed a tetramer, which was confirmed by chemical cross-linking. Single-particle analysis of cryo-electron microscope images was performed to depict the overall shape of the purified protein. The three-dimensional structure of MCA2 was reconstructed at a resolution of 26 Å from 5,500 particles and appears to comprise a small transmembrane region and large cytoplasmic region.

  12. Remote maintenance development for ITER

    Energy Technology Data Exchange (ETDEWEB)

    Tada, Eisuke [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Shibanuma, Kiyoshi

    1998-04-01

    This paper describes the overall ITER remote maintenance design concept developed mainly for in-vessel components such as diverters and blankets, and outlines the ITER R and D program to develop remote handling equipment and radiation hard components. Reactor structures inside the ITER cryostat must be maintained remotely due to DT operation, making remote handling technology basic to reactor design. The overall maintenance scenario and design concepts have been developed, and maintenance design feasibility, including fabrication and testing of full-scale in-vessel remote maintenance handling equipment and tool, is being verified. (author)

  13. Determining the cognitive structures of science teacher candidates on “evolution” through word association test

    Directory of Open Access Journals (Sweden)

    Arzu ÖNEL

    2016-04-01

    Full Text Available This study tried to determine the conceptual comprehension of science teacher candidates on evolution. As part of this target, the Word Association Test was applied. This study was conducted with the participation of 146 teacher candidates studying in the Department of Science Education. Of the 146 teacher candidates, 89 mostly wrote the words; “evolution” (f=43, “Darwin” (f=36, and “ape” (f=10 as primary concepts in the word association test. This result illustrated that when the word “evolution” was pronounced, 61% of teacher candidates firstly remembered these three words as primary concepts. This study has demonstrated once more that there are misunderstandings and missing data on the evolutionary theory despite the past 156 years from the emergence of this theory.

  14. Comparative gene expression analysis of avian embryonic facial structures reveals new candidates for human craniofacial disorders.

    Science.gov (United States)

    Brugmann, S A; Powder, K E; Young, N M; Goodnough, L H; Hahn, S M; James, A W; Helms, J A; Lovett, M

    2010-03-01

    Mammals and birds have common embryological facial structures, and appear to employ the same molecular genetic developmental toolkit. We utilized natural variation found in bird beaks to investigate what genes drive vertebrate facial morphogenesis. We employed cross-species microarrays to describe the molecular genetic signatures, developmental signaling pathways and the spectrum of transcription factor (TF) gene expression changes that differ between cranial neural crest cells in the developing beaks of ducks, quails and chickens. Surprisingly, we observed that the neural crest cells established a species-specific TF gene expression profile that predates morphological differences between the species. A total of 232 genes were differentially expressed between the three species. Twenty-two of these genes, including Fgfr2, Jagged2, Msx2, Satb2 and Tgfb3, have been previously implicated in a variety of mammalian craniofacial defects. Seventy-two of the differentially expressed genes overlap with un-cloned loci for human craniofacial disorders, suggesting that our data will provide a valuable candidate gene resource for human craniofacial genetics. The most dramatic changes between species were in the Wnt signaling pathway, including a 20-fold up-regulation of Dkk2, Fzd1 and Wnt1 in the duck compared with the other two species. We functionally validated these changes by demonstrating that spatial domains of Wnt activity differ in avian beaks, and that Wnt signals regulate Bmp pathway activity and promote regional growth in facial prominences. This study is the first of its kind, extending on previous work in Darwin's finches and provides the first large-scale insights into cross-species facial morphogenesis.

  15. Iterative methods for mixed finite element equations

    Science.gov (United States)

    Nakazawa, S.; Nagtegaal, J. C.; Zienkiewicz, O. C.

    1985-01-01

    Iterative strategies for the solution of indefinite system of equations arising from the mixed finite element method are investigated in this paper with application to linear and nonlinear problems in solid and structural mechanics. The augmented Hu-Washizu form is derived, which is then utilized to construct a family of iterative algorithms using the displacement method as the preconditioner. Two types of iterative algorithms are implemented. Those are: constant metric iterations which does not involve the update of preconditioner; variable metric iterations, in which the inverse of the preconditioning matrix is updated. A series of numerical experiments is conducted to evaluate the numerical performance with application to linear and nonlinear model problems.

  16. Solution structures of the acyl carrier protein domain from the highly reducing type I iterative polyketide synthase CalE8.

    Directory of Open Access Journals (Sweden)

    Jackwee Lim

    Full Text Available Biosynthesis of the enediyne natural product calicheamicins γ(1 (I in Micromonospora echinospora ssp. calichensis is initiated by the iterative polyketide synthase (PKS CalE8. Recent studies showed that CalE8 produces highly conjugated polyenes as potential biosynthetic intermediates and thus belongs to a family of highly-reducing (HR type I iterative PKSs. We have determined the NMR structure of the ACP domain (meACP of CalE8, which represents the first structure of a HR type I iterative PKS ACP domain. Featured by a distinct hydrophobic patch and a glutamate-residue rich acidic patch, meACP adopts a twisted three-helix bundle structure rather than the canonical four-helix bundle structure. The so-called 'recognition helix' (α2 of meACP is less negatively charged than the typical type II ACPs. Although loop-2 exhibits greater conformational mobility than other regions of the protein with a missing short helix that can be observed in most ACPs, two bulky non-polar residues (Met(992, Phe(996 from loop-2 packed against the hydrophobic protein core seem to restrict large movement of the loop and impede the opening of the hydrophobic pocket for sequestering the acyl chains. NMR studies of the hydroxybutyryl- and octanoyl-meACP confirm that meACP is unable to sequester the hydrophobic chains in a well-defined central cavity. Instead, meACP seems to interact with the octanoyl tail through a distinct hydrophobic patch without involving large conformational change of loop-2. NMR titration study of the interaction between meACP and the cognate thioesterase partner CalE7 further suggests that their interaction is likely through the binding of CalE7 to the meACP-tethered polyene moiety rather than direct specific protein-protein interaction.

  17. Iterative initial condition reconstruction

    Science.gov (United States)

    Schmittfull, Marcel; Baldauf, Tobias; Zaldarriaga, Matias

    2017-07-01

    Motivated by recent developments in perturbative calculations of the nonlinear evolution of large-scale structure, we present an iterative algorithm to reconstruct the initial conditions in a given volume starting from the dark matter distribution in real space. In our algorithm, objects are first moved back iteratively along estimated potential gradients, with a progressively reduced smoothing scale, until a nearly uniform catalog is obtained. The linear initial density is then estimated as the divergence of the cumulative displacement, with an optional second-order correction. This algorithm should undo nonlinear effects up to one-loop order, including the higher-order infrared resummation piece. We test the method using dark matter simulations in real space. At redshift z =0 , we find that after eight iterations the reconstructed density is more than 95% correlated with the initial density at k ≤0.35 h Mpc-1 . The reconstruction also reduces the power in the difference between reconstructed and initial fields by more than 2 orders of magnitude at k ≤0.2 h Mpc-1 , and it extends the range of scales where the full broadband shape of the power spectrum matches linear theory by a factor of 2-3. As a specific application, we consider measurements of the baryonic acoustic oscillation (BAO) scale that can be improved by reducing the degradation effects of large-scale flows. In our idealized dark matter simulations, the method improves the BAO signal-to-noise ratio by a factor of 2.7 at z =0 and by a factor of 2.5 at z =0.6 , improving standard BAO reconstruction by 70% at z =0 and 30% at z =0.6 , and matching the optimal BAO signal and signal-to-noise ratio of the linear density in the same volume. For BAO, the iterative nature of the reconstruction is the most important aspect.

  18. Embeddings of Iteration Trees

    OpenAIRE

    Mitchell, William

    1992-01-01

    This paper, dating from May 1991, contains preliminary (and unpublishable) notes on investigations about iteration trees. They will be of interest only to the specialist. In the first two sections I define notions of support and embeddings for tree iterations, proving for example that every tree iteration is a direct limit of finite tree iterations. This is a generalization to models with extenders of basic ideas of iterated ultrapowers using only ultrapowers. In the final section (which is m...

  19. The ITER project construction status

    Science.gov (United States)

    Motojima, O.

    2015-10-01

    The pace of the ITER project in St Paul-lez-Durance, France is accelerating rapidly into its peak construction phase. With the completion of the B2 slab in August 2014, which will support about 400 000 metric tons of the tokamak complex structures and components, the construction is advancing on a daily basis. Magnet, vacuum vessel, cryostat, thermal shield, first wall and divertor structures are under construction or in prototype phase in the ITER member states of China, Europe, India, Japan, Korea, Russia, and the United States. Each of these member states has its own domestic agency (DA) to manage their procurements of components for ITER. Plant systems engineering is being transformed to fully integrate the tokamak and its auxiliary systems in preparation for the assembly and operations phase. CODAC, diagnostics, and the three main heating and current drive systems are also progressing, including the construction of the neutral beam test facility building in Padua, Italy. The conceptual design of the Chinese test blanket module system for ITER has been completed and those of the EU are well under way. Significant progress has been made addressing several outstanding physics issues including disruption load characterization, prediction, avoidance, and mitigation, first wall and divertor shaping, edge pedestal and SOL plasma stability, fuelling and plasma behaviour during confinement transients and W impurity transport. Further development of the ITER Research Plan has included a definition of the required plant configuration for 1st plasma and subsequent phases of ITER operation as well as the major plasma commissioning activities and the needs of the accompanying R&D program to ITER construction by the ITER parties.

  20. Effects of Complex Symmetry-Breakings on Alpha Particle Power Loads on First Wall Structures and Equilibrium in ITER

    Energy Technology Data Exchange (ETDEWEB)

    Shinohara, K. [Japan Atomic Energy Agency (JAEA), Naka; Kurki-Suonio, T. [Aalto University, Finland; Spong, Donald A [ORNL; Asunta, O. [Aalto University, Finland; Tani, K. [Japan Atomic Energy Agency (JAEA), Naka; Strumberger, E. [Max Planck Institute for Plasma Physics, Garching, Germany; Briguglio, S. [EURATOM / ENEA, Italy; Koskela, T. [Aalto University, Finland; Vlad, G. [EURATOM / ENEA, Italy; Günter, S. [Max-Planck Institute, Garching, Germany; Kramer, G. [Princeton Plasma Physics Laboratory (PPPL); Putvinski, S. [ITER Organization, Cadarache, France; Hamamatsu, K. [Japan Atomic Energy Agency (JAEA), Naka

    2011-01-01

    Within the ITPA Topical Group on Energetic Particles, we have investigated the impact that various mechanisms breaking the tokamak axisymmetry can have on the fusion alpha particle confinement in ITER as well as on the wall power loads due to these alphas. In addition to the well-known TF ripple, the 3D effect due to ferromagnetic materials (in ferritic inserts and test blanket modules) and ELM mitigation coils are included in these mechanisms. ITER scenario 4 was chosen since, due to its lower plasma current, it is more vulnerable for various off-normal features. First, the validity of using a 2D equilibrium was investigated: a 3D equilibrium was reconstructed using the VMEC code, and it was verified that no 3D equilibrium reconstruction is needed but it is sufficient to add the vacuum field perturbations onto an axisymmetric equilibrium. Then the alpha particle confinement was studied using three independent codes, ASCOT, DELTA5D and F3D OFMC, all of which assume MHD quiescent background plasma and no anomalous diffusion. All the codes gave a loss power fraction of about 0.2%. The distribution of the peak power load was found to depend on the first wall shape. We also made the first attempt to accommodate the effect of fast-ion-related MHD on the wall loads in ITER using the HMGC and ASCOT codes. The power flux to the wall was found to increase due to the redistribution of fast ions by the MHD activity. Furthermore, the effect of the ELM mitigation field on the fast-ion confinement was addressed by simulating NBI ions with the F3D OFMC code. The loss power fraction of NBI ions was found to increase from 0.3% without the ELM mitigation field to 4-5% with the ELM mitigation field.

  1. Quantum iterated function systems.

    Science.gov (United States)

    Łoziński, Artur; Zyczkowski, Karol; Słomczyński, Wojciech

    2003-10-01

    An iterated function system (IFS) is defined by specifying a set of functions in a classical phase space, which act randomly on an initial point. In an analogous way, we define a quantum IFS (QIFS), where functions act randomly with prescribed probabilities in the Hilbert space. In a more general setting, a QIFS consists of completely positive maps acting in the space of density operators. This formalism is designed to describe certain problems of nonunitary quantum dynamics. We present exemplary classical IFSs, the invariant measure of which exhibits fractal structure, and study properties of the corresponding QIFSs and their invariant states.

  2. Non-ideal operating conditions of the ion source prototype for the ITER neutral beam injector due to thermal deformation of the support structure.

    Science.gov (United States)

    Sartori, E; Pavei, M; Marcuzzi, D; Zaccaria, P

    2014-02-01

    The beam formation and acceleration of the ITER neutral beam injector will be studied in the full-scale ion source, Source for Production of Ions of Deuterium Extracted from a RF plasma (SPIDER). It will be able to sustain 40 A deuterium ion beam during 1-h pulses. The operating conditions of its multi-aperture electrodes will diverge from ideality, as a consequence of inhomogeneous heating and thermally induced deformations in the support structure of the extraction and acceleration grids, which operate at different temperatures. Meeting the requirements on the aperture alignment and distance between the grids with such a large number of apertures (1280) and the huge support structures constitute a challenge. Examination of the structure thermal deformation in transient and steady conditions has been carried out, evaluating their effect on the beam performance: the paper describes the analyses and the solutions proposed to mitigate detrimental effects.

  3. Non-ideal operating conditions of the ion source prototype for the ITER neutral beam injector due to thermal deformation of the support structure

    Science.gov (United States)

    Sartori, E.; Pavei, M.; Marcuzzi, D.; Zaccaria, P.

    2014-02-01

    The beam formation and acceleration of the ITER neutral beam injector will be studied in the full-scale ion source, Source for Production of Ions of Deuterium Extracted from a RF plasma (SPIDER). It will be able to sustain 40 A deuterium ion beam during 1-h pulses. The operating conditions of its multi-aperture electrodes will diverge from ideality, as a consequence of inhomogeneous heating and thermally induced deformations in the support structure of the extraction and acceleration grids, which operate at different temperatures. Meeting the requirements on the aperture alignment and distance between the grids with such a large number of apertures (1280) and the huge support structures constitute a challenge. Examination of the structure thermal deformation in transient and steady conditions has been carried out, evaluating their effect on the beam performance: the paper describes the analyses and the solutions proposed to mitigate detrimental effects.

  4. Non-ideal operating conditions of the ion source prototype for the ITER neutral beam injector due to thermal deformation of the support structure

    Energy Technology Data Exchange (ETDEWEB)

    Sartori, E., E-mail: emanuele.sartori@igi.cnr.it; Pavei, M.; Marcuzzi, D.; Zaccaria, P. [Consorzio RFX, Euratom-ENEA Association, Corso Stati Uniti 4, 35127 Padova (Italy)

    2014-02-15

    The beam formation and acceleration of the ITER neutral beam injector will be studied in the full-scale ion source, Source for Production of Ions of Deuterium Extracted from a RF plasma (SPIDER). It will be able to sustain 40 A deuterium ion beam during 1-h pulses. The operating conditions of its multi-aperture electrodes will diverge from ideality, as a consequence of inhomogeneous heating and thermally induced deformations in the support structure of the extraction and acceleration grids, which operate at different temperatures. Meeting the requirements on the aperture alignment and distance between the grids with such a large number of apertures (1280) and the huge support structures constitute a challenge. Examination of the structure thermal deformation in transient and steady conditions has been carried out, evaluating their effect on the beam performance: the paper describes the analyses and the solutions proposed to mitigate detrimental effects.

  5. ITER LHCD plans and design

    Energy Technology Data Exchange (ETDEWEB)

    Bibet, Ph.; Beaumont, B.; Delpech, L.; Ekedahl, A.; Kazarian, F.; Litaudon, X.; Prou, M. [CEA Cadarache, Dept. de Recherches sur la Fusion Controlee (DRFC), 13 - Saint-Paul-lez-Durance (France); Belo, J.H.; Bizarro, J.P.S. [Centro de Fusao Nuclear, Associacao Euratom-IST, Instituto Superior Tecnico, Lisboa (Portugal); Granucci, G. [Associazione EURATOM-ENEA sulla Fusione, Milano (Italy); Kuzikov, S. [Institute of Applied Physics, Nizhny Novgorod (Russian Federation); Mailloux, J. [Euratom/UKAEA Fusion Association, Culham Science Centre, Abingdon (United Kingdom); Mirizzi, F.; Pericoli, V.; Tuccillo, A.A. [Association Euratom-ENEA sulla Fusione, Centro Ricerche Energia Frascati (Italy); Rantamaki, K. [Association Euratom-Tekes, VTT (Finland)

    2005-07-01

    LH waves experimentally exhibit the highest Current Drive efficiency at low plasma temperature, therefore they are the most suitable candidates for controlling the current profile in the off axis part of ITER Steady State plasmas. For this purpose, a 5 GHz, 20 MW CW LH system has been designed, that relies on a generator made of 24 klystrons, 1 MW each, 60 metres long circular oversized transmission lines, one antenna, based on the Passive Active Multi-function (PAM) concept. High reliability of the launcher is achieved, by limiting the power density to 33 MW/m{sup 2}. Together with the overall system description, the present results achieved toward ITER are presented. The different ongoing project are listed. The remaining outstanding problems are depicted. (authors)

  6. Catalytic Metal Free Production of Large Cage Structure Carbon Particles: A Candidate for Hydrogen Storage

    Science.gov (United States)

    Kimura, Yuki; Nuth, Joseph A., III; Ferguson, Frank T.

    2005-01-01

    We will demonstrate that carbon particles consisting of large cages can be produced without catalytic metal. The carbon particles were produced in CO gas as well as by introduction of 5% methane gas into the CO gas. The gas-produced carbon particles were able to absorb approximately 16.2 wt% of hydrogen. This value is 2.5 times higher than the 6.5 wt% goal for the vehicular hydrogen storage proposed by the Department of Energy in the USA. Therefore, we believe that this carbon particle is an excellent candidate for hydrogen storage for fuel cells.

  7. Strategy for solving a coupled problem of the electromagnetic load analysis and design optimization for local conducting structures to support the ITER blanket development

    Energy Technology Data Exchange (ETDEWEB)

    Rozov, Vladimir, E-mail: vladimir.rozov@iter.org [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul-lez-Durance (France); Belyakov, V.; Kukhtin, V.; Lamzin, E.; Mazul, I.; Sytchevsky, S. [D.V. Efremov Scientific Research Institute, 196641 St. Petersburg (Russian Federation)

    2014-11-15

    Highlights: • We present the way of modeling transient electro-magnetic loads on local conductive domains in the large magnetic system. • Simplification is achieved by decomposing of the problem, multi-scale integral-differential modeling and use of integral parameters. • The intrinsic scale of loads on a localized conductor with eddy is quantified through the load susceptibility tensor. • Solution is searched as response of a simple equivalent dynamic simulator, using control theory methods. • The concept is exemplified with multi-scenario assessment of EM eddy loads on ITER blanket modules. - Abstract: The complexity of the electromagnetic (EM) response of the tokamak structures is one of the key and design-driving issues for the ITER. We consider the specifics of the assessment of ponderomotive forces, acting on local components of a large electro-physical device during electromagnetic transients. A strategy and approach is proposed for the operative EM loads modeling and analysis that enables design optimization at early phases of development. The paper describes a method of principal simplification of the mathematical model, based on the analysis and exploiting specific features and peculiarities of the relevant technical problem, determined by the design and operation of the device and system under consideration. The application of the method for predictive EM loads analysis and corresponding numerical calculations are exemplified for the localized ITER blanket components — shield modules. The example demonstrates the efficiency of EM load analysis in complex electromagnetic systems via a set of simplified models with different scope, contents and level of detail.

  8. TIG and HIP joining of Reduced Activation Ferrite/Martensitic steel for the Korean ITER-TBM

    Energy Technology Data Exchange (ETDEWEB)

    Ku, Duck Young [ITER Korea, National Fusion Research Institute, Gwahangno 113, Yuseong-gu, Daejeon 305-333 (Korea, Republic of); Oh, Seungjin, E-mail: osj0423@gmail.com [Nuclear Engineering and Technology Institute, KHNP, 508 Keumbyeong-ro, Yuseong-gu, Daejeon 305-343 (Korea, Republic of); Ahn, Mu-Young; Yu, In-Keun; Kim, Duck-Hoi; Cho, Seungyon [ITER Korea, National Fusion Research Institute, Gwahangno 113, Yuseong-gu, Daejeon 305-333 (Korea, Republic of); Choi, Im-Sub; Kwon, Ki-Bum [Soles Co. LTD., 9-1 Horim-dong, Dalseo-gu, Daegu 704-249 (Korea, Republic of)

    2011-10-01

    Korea is developing a Helium Cooled Solid Breeder Test Blanket Module for ITER. The primary candidate structural material is a Reduced Activation Ferritic/Martensitic steel. The complex TBM structure requires developing joining technologies for successful fabrication. The characteristics of Tungsten Inert Gas welding and Hot Isostatic Pressing joining of RAFM steel were investigated. Metallurgical examinations showed that the steel grain size was increased after HIP joining and recovered by post joining heat treatment. Both TIG welding and HIP joining are found to be acceptable for ITER TBM based on mechanical tests and microstructure examination.

  9. Iterative solution of the reduced eigenvalue problem

    Energy Technology Data Exchange (ETDEWEB)

    Sauer, G. (Technischer Ueberwachungs-Verein Bayern e.V., Muenchen (Germany, F.R.))

    1991-04-01

    The Guyan method of reducing the stiffness and mass matrices of large linear structures introduces errors in the reduced mass matrix. These errors cannot be completely avoided even if the analysis coordinates are chosen optimally. However, they can be elimiated by iterating on the eigenvectors found from the Guyan reduced matrices. The necessary iteration steps follow directly from the eigenvalue problem. The resulting iteration procedures are presented and applied to two test problems showing that the iterations enable the exact eigensolutions to be extracted. All errors from the Guyan reduced matrices are removed or substantially decreased. (orig.).

  10. IHadoop: Asynchronous iterations for MapReduce

    KAUST Repository

    Elnikety, Eslam Mohamed Ibrahim

    2011-11-01

    MapReduce is a distributed programming frame-work designed to ease the development of scalable data-intensive applications for large clusters of commodity machines. Most machine learning and data mining applications involve iterative computations over large datasets, such as the Web hyperlink structures and social network graphs. Yet, the MapReduce model does not efficiently support this important class of applications. The architecture of MapReduce, most critically its dataflow techniques and task scheduling, is completely unaware of the nature of iterative applications; tasks are scheduled according to a policy that optimizes the execution for a single iteration which wastes bandwidth, I/O, and CPU cycles when compared with an optimal execution for a consecutive set of iterations. This work presents iHadoop, a modified MapReduce model, and an associated implementation, optimized for iterative computations. The iHadoop model schedules iterations asynchronously. It connects the output of one iteration to the next, allowing both to process their data concurrently. iHadoop\\'s task scheduler exploits inter-iteration data locality by scheduling tasks that exhibit a producer/consumer relation on the same physical machine allowing a fast local data transfer. For those iterative applications that require satisfying certain criteria before termination, iHadoop runs the check concurrently during the execution of the subsequent iteration to further reduce the application\\'s latency. This paper also describes our implementation of the iHadoop model, and evaluates its performance against Hadoop, the widely used open source implementation of MapReduce. Experiments using different data analysis applications over real-world and synthetic datasets show that iHadoop performs better than Hadoop for iterative algorithms, reducing execution time of iterative applications by 25% on average. Furthermore, integrating iHadoop with HaLoop, a variant Hadoop implementation that caches

  11. Turbo iterative equalization for HSDPA systems

    Institute of Scientific and Technical Information of China (English)

    WU QiHui; ZHAO ChunMing; WANG JinLong

    2007-01-01

    In this paper, a turbo iterative receiver structure with chip equalization is proposed for the 3G high-speed downlink packet access (HSDPA) systems. The receiver equalizes the channel prior to the dispreading and then performs two successive soft-output decisions, achieved by a soft-input soft-output (SISO) multi-code detector and a SISO turbo decoder through an iterative process. At each iteration, extrinsic information is extracted from detection and decoding stages and is then used as a priori information in the next iteration, just as in turbo decoding. Computer simulations show that the turbo iterative receiver structure with chip equalization offers significant performance gain over the traditional receiver structure.

  12. The Candidate Cluster and Protocluster Catalog (CCPC) of Spectroscopically Identified Structures Spanning 2.74 < z < 3.71

    Science.gov (United States)

    Franck, J. R.; McGaugh, S. S.

    2016-02-01

    We developed a search methodology to identify galaxy protoclusters at z\\gt 2.74 and implemented it on a sample of ˜14,000 galaxies with previously measured redshifts. The results of this search are recorded in the Candidate Cluster and Protocluster Catalog (CCPC). The catalog contains 12 clusters that are highly significant overdensities ({δ }{gal}\\gt 7), 6 of which were previously known. We also identify another 31 candidate protoclusters (including four previously identified structures) of lower overdensities. CCPC systems vary over a wide range of physical sizes and shapes, from small, compact groups to large, extended, and filamentary collections of galaxies. This variety persists in the range from z = 3.71 to z = 2.74. These structures exist as galaxy overdensities ({δ }{gal}) with a mean value of 2, similar to the values found for other protoclusters in the literature. The median number of galaxies for CCPC systems is 11. Virial mass estimates are large for these redshifts, with 13 cases apparently having M\\gt {10}15 {M}⊙ . If these systems are virialized, such masses would pose a challenge to ΛCDM.

  13. The candidate cluster and protocluster catalog (CCPC) of spectroscopically identified structures spanning $2.74 < z < 3.71$

    CERN Document Server

    Franck, J R

    2015-01-01

    We have developed a search methodology to identify galaxy protoclusters at $z>2.74$, and implemented it on a sample of $\\sim$14,000 galaxies with previously measured redshifts. The results of this search are recorded in the Candidate Cluster and Protocluster Catalog (CCPC). The catalog contains 12 clusters that are highly significant overdensities ($\\delta_{gal}>7$), 6 of which are previously known. We also identify another 31 candidate protoclusters (including 4 previously identified structures) of lower overdensity. CCPC systems vary over a wide range of physical sizes and shapes, from small, compact groups to large, extended, and filamentary collections of galaxies. This variety persists over the range from $z=3.71$ to $z=2.74$. These structures exist as galaxy overdensities ($\\delta_{gal}$) with a mean value of 2, similar to the values found for other protoclusters in the literature. The median number of galaxies for CCPC systems is 11. Virial mass estimates are large for these redshifts, with thirteen ca...

  14. Development and preliminary validation of a semi-structured interview for the screening of law enforcement candidates.

    Science.gov (United States)

    Varela, J G; Scogin, F R; Vipperman, R K

    1999-01-01

    A standard practice among most law enforcement agencies is to include psychological screening in the selection of job candidates. Although the use of personality tests in predicting job performance of law enforcement officers has received empirical support (e.g., the Minnesota Multiphasic Personality Inventory, the Inwald Personality Inventory), there is a conspicuous absence of data regarding the reliability and validity of interview procedures. The present study represents the first step in the development of a standardized, semi-structured interview for use in the screening of law enforcement personnel. This interview, the Law Enforcement Candidate Interview, was constructed using content areas drawn from measures used in the screening of law enforcement personnel (e.g., Inwald Personality Inventory) and assessment of personality functioning (Structured Clinical Interview for DSM-III-R Personality Disorders). This interview was then administered by two doctoral students to a group of law enforcement academy cadets (n=34). A modest degree of inter-rater reliability was achieved, although internal consistency was somewhat lacking. Interview scores were correlated with measures of academy performance (final grade-point average and peer and supervisor ranking of academy performance). Results of these analyses suggest the LECI is a modest predictor of academy performance. Potential uses of the LECI and future research indications are outlined. Copyright 1999 John Wiley & Sons, Ltd.

  15. Investigation of candidate data structures and search algorithms to support a knowledge based fault diagnosis system

    Science.gov (United States)

    Bosworth, Edward L., Jr.

    1987-01-01

    The focus of this research is the investigation of data structures and associated search algorithms for automated fault diagnosis of complex systems such as the Hubble Space Telescope. Such data structures and algorithms will form the basis of a more sophisticated Knowledge Based Fault Diagnosis System. As a part of the research, several prototypes were written in VAXLISP and implemented on one of the VAX-11/780's at the Marshall Space Flight Center. This report describes and gives the rationale for both the data structures and algorithms selected. A brief discussion of a user interface is also included.

  16. ISSA (iterative screening and structure analysis)—a new reduction method and its application to the tropospheric cloud chemical mechanism RACM/CAPRAM2.4

    Science.gov (United States)

    Mauersberger, G.

    An automated reduction method ISSA (iterative screening and structure analysis) has been developed. It is aimed at the analysis of complex atmospheric chemical multiphase mechanisms and produces reduced mechanisms for specifiable application purposes. Cyclic and non-cyclic reactions identified by a structure analysis are separately evaluated. The normalized valuation coefficients are calculated in a box model framework by using time-averaged reaction rates. Starting with a set of target species, important reactions and species are selected together in an iteration procedure. So, only one threshold value fixed for all box model scenarios is necessary. For every scenario a specific reduced mechanism is obtained. The sum of reactions and species included in the specific reduced mechanisms generates then the ISSA-reduced mechanism. All reactants in the reduced mechanism are included in the verification procedure where the concentrations simulated with the full and the reduced mechanism are compared. The maximum relative deviation of daily maxima was found to be a suitable deviation measure for atmospheric trace species concentrations. An application of the ISSA method to the large cloud chemical mechanism RACM/CAPRAM2.4 resulted in reduction rates of 55% for reactions (46% gas phase, 60% liquid phase), 23% for species, and 23% for phase transfers. The deviation between full and reduced mechanism averaged over all scenarios and reactants was 2.5%. The liquid-phase part of this application was compared with a condensed version of the CAPARAM2.4 mechanism developed simultaneously with the full version. It was found that these two reduced versions of CAPRAM2.4 differ significantly. Whereas the condensed version achieves good verification results only for the target species, the ISSA-reduced version reproduce very well the complete full mechanism results and should be useful for future large-scale models, which will include both detailed microphysics and complex (reduced

  17. Approximate Modified Policy Iteration

    CERN Document Server

    Scherrer, Bruno; Ghavamzadeh, Mohammad; Geist, Matthieu

    2012-01-01

    Modified policy iteration (MPI) is a dynamic programming (DP) algorithm that contains the two celebrated policy and value iteration methods. Despite its generality, MPI has not been thoroughly studied, especially its approximation form which is used when the state and/or action spaces are large or infinite. In this paper, we propose three approximate MPI (AMPI) algorithms that are extensions of the well-known approximate DP algorithms: fitted-value iteration, fitted-Q iteration, and classification-based policy iteration. We provide an error propagation analysis for AMPI that unifies those for approximate policy and value iteration. We also provide a finite-sample analysis for the classification-based implementation of AMPI (CBMPI), which is more general (and somehow contains) than the analysis of the other presented AMPI algorithms. An interesting observation is that the MPI's parameter allows us to control the balance of errors (in value function approximation and in estimating the greedy policy) in the fina...

  18. Delineation of candidate genes responsible for structural brain abnormalities in patients with terminal deletions of chromosome 6q27.

    Science.gov (United States)

    Peddibhotla, Sirisha; Nagamani, Sandesh C S; Erez, Ayelet; Hunter, Jill V; Holder, J Lloyd; Carlin, Mary E; Bader, Patricia I; Perras, Helene M F; Allanson, Judith E; Newman, Leslie; Simpson, Gayle; Immken, LaDonna; Powell, Erin; Mohanty, Aaron; Kang, Sung-Hae L; Stankiewicz, Pawel; Bacino, Carlos A; Bi, Weimin; Patel, Ankita; Cheung, Sau W

    2015-01-01

    Patients with terminal deletions of chromosome 6q present with structural brain abnormalities including agenesis of corpus callosum, hydrocephalus, periventricular nodular heterotopia, and cerebellar malformations. The 6q27 region harbors genes that are important for the normal development of brain and delineation of a critical deletion region for structural brain abnormalities may lead to a better genotype-phenotype correlation. We conducted a detailed clinical and molecular characterization of seven unrelated patients with deletions involving chromosome 6q27. All patients had structural brain abnormalities. Using array comparative genomic hybridization, we mapped the size, extent, and genomic content of these deletions. The smallest region of overlap spans 1.7 Mb and contains DLL1, THBS2, PHF10, and C6orf70 (ERMARD) that are plausible candidates for the causation of structural brain abnormalities. Our study reiterates the importance of 6q27 region in normal development of brain and helps identify putative genes in causation of structural brain anomalies.

  19. Do Clinical Clerks Provide Candidates with Adequate Formative Assessment during Objective Structured Clinical Examinations?

    Science.gov (United States)

    Reiter, Harold I.; Rosenfeld, Jack; Nandagopal, Kiruthiga; Eva, Kevin W.

    2004-01-01

    Context: Various research studies have examined the question of whether expert or non-expert raters, faculty or students, evaluators or standardized patients, give more reliable and valid summative assessments of performance on Objective Structured Clinical Examinations (OSCEs). Less studied has been the question of whether or not non-faculty…

  20. Applied iterative methods

    CERN Document Server

    Hageman, Louis A

    2004-01-01

    This graduate-level text examines the practical use of iterative methods in solving large, sparse systems of linear algebraic equations and in resolving multidimensional boundary-value problems. Assuming minimal mathematical background, it profiles the relative merits of several general iterative procedures. Topics include polynomial acceleration of basic iterative methods, Chebyshev and conjugate gradient acceleration procedures applicable to partitioning the linear system into a "red/black" block form, adaptive computational algorithms for the successive overrelaxation (SOR) method, and comp

  1. ITER test programme

    Science.gov (United States)

    Abdou, M.; Baker, C.; Casini, G.

    1991-07-01

    The International Thermonuclear Experimental Reactor (ITER) was designed to operate in two phases. The first phase, which lasts for 6 years, is devoted to machine checkout and physics testing. The second phase lasts for 8 years and is devoted primarily to technology testing. This report describes the technology test program development for ITER, the ancillary equipment outside the torus necessary to support the test modules, the international collaboration aspects of conducting the test program on ITER, the requirements on the machine major parameters and the R and D program required to develop the test modules for testing in ITER.

  2. Iterative Knowledge-Based Scoring Functions Derived from Rigid and Flexible Decoy Structures: Evaluation with the 2013 and 2014 CSAR Benchmarks.

    Science.gov (United States)

    Yan, Chengfei; Grinter, Sam Z; Merideth, Benjamin Ryan; Ma, Zhiwei; Zou, Xiaoqin

    2016-06-27

    In this study, we developed two iterative knowledge-based scoring functions, ITScore_pdbbind(rigid) and ITScore_pdbbind(flex), using rigid decoy structures and flexible decoy structures, respectively, that were generated from the protein-ligand complexes in the refined set of PDBbind 2012. These two scoring functions were evaluated using the 2013 and 2014 CSAR benchmarks. The results were compared with the results of two other scoring functions, the Vina scoring function and ITScore, the scoring function that we previously developed from rigid decoy structures for a smaller set of protein-ligand complexes. A graph-based method was developed to evaluate the root-mean-square deviation between two conformations of the same ligand with different atom names and orders due to different file preparations, and the program is freely available. Our study showed that the two new scoring functions developed from the larger training set yielded significantly improved performance in binding mode predictions. For binding affinity predictions, all four scoring functions showed protein-dependent performance. We suggest the development of protein-family-dependent scoring functions for accurate binding affinity prediction.

  3. Event-horizon-scale structure in the supermassive black hole candidate at the Galactic Centre

    CERN Document Server

    Doeleman, Sheperd; Rogers, Alan E E; Plambeck, Richard; Freund, Robert; Tilanus, Remo P J; Friberg, Per; Ziurys, Lucy M; Moran, James M; Corey, Brian; Young, Ken H; Smythe, Daniel L; Titus, Michael; Marrone, Daniel P; Cappallo, Roger J; Bock, Douglas C J; Bower, Geoffrey C; Chamberlin, Richard; Davis, Gary R; Krichbaum, Thomas P; Lamb, James; Maness, Holly; Niell, Arthur E; Roy, Alan; Strittmatter, Peter; Werthimer, Daniel; Whitney, Alan R; Woody, David

    2008-01-01

    The cores of most galaxies are thought to harbour supermassive black holes, which power galactic nuclei by converting the gravitational energy of accreting matter into radiation (ref 1). Sagittarius A*, the compact source of radio, infrared and X-ray emission at the centre of the Milky Way, is the closest example of this phenomenon, with an estimated black hole mass that is 4 million times that of the Sun (refs. 2,3). A long-standing astronomical goal is to resolve structures in the innermost accretion flow surrounding Sgr A* where strong gravitational fields will distort the appearance of radiation emitted near the black hole. Radio observations at wavelengths of 3.5 mm and 7 mm have detected intrinsic structure in Sgr A*, but the spatial resolution of observations at these wavelengths is limited by interstellar scattering (refs. 4-7). Here we report observations at a wavelength of 1.3 mm that set a size of 37 (+16, -10; 3-sigma) microarcseconds on the intrinsic diameter of Sgr A*. This is less than the expe...

  4. Techniques in Iterative Proton CT Image Reconstruction

    CERN Document Server

    Penfold, Scott

    2015-01-01

    This is a review paper on some of the physics, modeling, and iterative algorithms in proton computed tomography (pCT) image reconstruction. The primary challenge in pCT image reconstruction lies in the degraded spatial resolution resulting from multiple Coulomb scattering within the imaged object. Analytical models such as the most likely path (MLP) have been proposed to predict the scattered trajectory from measurements of individual proton location and direction before and after the object. Iterative algorithms provide a flexible tool with which to incorporate these models into image reconstruction. The modeling leads to a large and sparse linear system of equations that can efficiently be solved by projection methods-based iterative algorithms. Such algorithms perform projections of the iterates onto the hyperlanes that are represented by the linear equations of the system. They perform these projections in possibly various algorithmic structures, such as block-iterative projections (BIP), string-averaging...

  5. Iteration, Not Induction

    Science.gov (United States)

    Dobbs, David E.

    2009-01-01

    The main purpose of this note is to present and justify proof via iteration as an intuitive, creative and empowering method that is often available and preferable as an alternative to proofs via either mathematical induction or the well-ordering principle. The method of iteration depends only on the fact that any strictly decreasing sequence of…

  6. ITER at Cadarache; ITER a Cadarache

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-06-15

    This public information document presents the ITER project (International Thermonuclear Experimental Reactor), the definition of the fusion, the international cooperation and the advantages of the project. It presents also the site of Cadarache, an appropriate scientifical and economical environment. The last part of the documentation recalls the historical aspect of the project and the today mobilization of all partners. (A.L.B.)

  7. Immunostimulation by synthetic lipopeptide based vaccine candidates: structure-activity relationships.

    Directory of Open Access Journals (Sweden)

    Mehfuz eZaman

    2013-10-01

    Full Text Available Peptide based vaccines offer several advantages over conventional whole organism or protein approaches by offering improved purity and specificity in inducing immune response. However, peptides alone are generally non-immunogenic. Concerns remain about the toxicity of adjuvants which are critical for immunogenicity of synthetic peptides. The use of lipopeptides in peptide vaccines is currently under intensive investigation because potent immune responses can be generated without the use of adjuvant (thus are self-adjuvanting. Several lipopeptides derived from microbial origin, and their synthetic versions or simpler fatty acid moieties impart this self-adjuvanting activity by signalling via Toll-like receptor 2 (TLR2. Engagement of this innate immune receptor on antigen-presenting cell leads to the initiation and development of potent immune responses. Therefore optimization of lipopeptides to enhance TLR2-mediated activation is a promising strategy for vaccine development. Considerable structure-activity relationships that determine TLR2 binding and consequent stimulation of innate immune responses have been investigated for a range of lipopeptides. In this review we address the development of lipopeptide vaccines, mechanism of TLR2 recognition, and immune activation. An overview is provided of the best studied lipopeptide vaccine systems.

  8. Alternative modelling of brittle structures in a sub-area of the SKB candidate area at Forsmark, eastern Sweden.

    Energy Technology Data Exchange (ETDEWEB)

    Askling, Per; Tiren, Sven A.; Beckholmen, Monica; Straeng, Thomas (Geosigma AB, Uppsala (Sweden))

    2008-11-15

    One way to test the confidence of a presented model is to construct an alternative model. Such work is cognitive process of skill acquisition and also a process of understanding data in the sense of sorting and classifying data. This is of particular interest for the Swedish Radiation Safety Authority (SSM) in their technical review of SKB's on-going site investigation programme for potential repository sites. In this study, an alternative brittle deformation model of a selected part of the SKB candidate area in eastern Sweden was constructed. The input data set was obtained from SKB's database SICADA and is a selected set of data from five cored boreholes drilled from two drill-sites and comprises geophysical borehole logs, geological core-logs, hydrological logs (PFL; Posiva Flow Log) and borehole deviation measurements. Statistical cluster analysis applied on the geophysical borehole data were used to obtain the locations of bedrock with contrasting physical characteristics similar to those of brittle deformation zones. The cluster analysis is an objective procedure, contrasting with SKB's more subjective approach to the single-hole interpretation. Thus some differences are expected which could illustrate the effect of methodology that includes subjective 'expert judgement.' and indicate the possibility of alternative interpretations. The information about brittle structures in the geological boreholes logs was sorted and classification was made according to character of the structures (all fractures, open fractures, partly open fractures, frequency, orientate on/identification of fracture sets, sections of crush rock, and alteration). A separate study was performed to relate rock alteration with structures. The resolution applied in the fracture statistics is one metre, i.e. all studied entities were expressed per metre borehole length. All clusters were structurally characterized by the fractures inside the clusters (orientation and

  9. Structural, phylogenetic and docking studies of D-amino acid oxidase activator (DAOA, a candidate schizophrenia gene

    Directory of Open Access Journals (Sweden)

    Sehgal Sheikh

    2013-01-01

    Full Text Available Abstract Background Schizophrenia is a neurodegenerative disorder that occurs worldwide and can be difficult to diagnose. It is the foremost neurological disorder leading to suicide among patients in both developed and underdeveloped countries. D-amino acid oxidase activator (DAOA, also known as G72, is directly implicated in the glutamateric hypothesis of schizophrenia. It activates D-amino acid oxidase, which oxidizes D-serine, leading to modulation of the N-methyl-D-aspartate receptor. Methods MODELLER (9v10 was utilized to generate three dimensional structures of the DAOA candidate gene. The HOPE server was used for mutational analysis. The Molecular Evolutionary Genetics Analysis (MEGA5 tool was utilized to reconstruct the evolutionary history of the candidate gene DAOA. AutoDock was used for protein-ligand docking and Gramm-X and PatchDock for protein-protein docking. Results A suitable template (1ZCA was selected by employing BLASTp on the basis of 33% query coverage, 27% identity and E-value 4.9. The Rampage evaluation tool showed 91.1% favored region, 4.9% allowed region and 4.1% outlier region in DAOA. ERRAT demonstrated that the predicted model had a 50.909% quality factor. Mutational analysis of DAOA revealed significant effects on hydrogen bonding and correct folding of the DAOA protein, which in turn affect protein conformation. Ciona was inferred as the outgroup. Tetrapods were in their appropriate clusters with bifurcations. Human amino acid sequences are conserved, with chimpanzee and gorilla showing more than 80% homology and bootstrap value based on 1000 replications. Molecular docking analysis was employed to elucidate the binding mode of the reported ligand complex for DAOA. The docking experiment demonstrated that DAOA is involved in major amino acid interactions: the residues that interact most strongly with the ligand C28H28N3O5PS2 are polar but uncharged (Gln36, Asn38, Thr 122 and non-polar hydrophobic (Ile119, Ser171

  10. Accelerated iterative beam angle selection in IMRT

    Energy Technology Data Exchange (ETDEWEB)

    Bangert, Mark, E-mail: m.bangert@dkfz.de [Department of Medical Physics in Radiation Oncology, German Cancer Research Center—DKFZ, Im Neuenheimer Feld 280, Heidelberg D-69120 (Germany); Unkelbach, Jan [Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114 (United States)

    2016-03-15

    Purpose: Iterative methods for beam angle selection (BAS) for intensity-modulated radiation therapy (IMRT) planning sequentially construct a beneficial ensemble of beam directions. In a naïve implementation, the nth beam is selected by adding beam orientations one-by-one from a discrete set of candidates to an existing ensemble of (n − 1) beams. The best beam orientation is identified in a time consuming process by solving the fluence map optimization (FMO) problem for every candidate beam and selecting the beam that yields the largest improvement to the objective function value. This paper evaluates two alternative methods to accelerate iterative BAS based on surrogates for the FMO objective function value. Methods: We suggest to select candidate beams not based on the FMO objective function value after convergence but (1) based on the objective function value after five FMO iterations of a gradient based algorithm and (2) based on a projected gradient of the FMO problem in the first iteration. The performance of the objective function surrogates is evaluated based on the resulting objective function values and dose statistics in a treatment planning study comprising three intracranial, three pancreas, and three prostate cases. Furthermore, iterative BAS is evaluated for an application in which a small number of noncoplanar beams complement a set of coplanar beam orientations. This scenario is of practical interest as noncoplanar setups may require additional attention of the treatment personnel for every couch rotation. Results: Iterative BAS relying on objective function surrogates yields similar results compared to naïve BAS with regard to the objective function values and dose statistics. At the same time, early stopping of the FMO and using the projected gradient during the first iteration enable reductions in computation time by approximately one to two orders of magnitude. With regard to the clinical delivery of noncoplanar IMRT treatments, we could

  11. Systematic Structural Characterization of Metabolites in Arabidopsis via Candidate Substrate-Product Pair Networks[C][W

    Science.gov (United States)

    Morreel, Kris; Saeys, Yvan; Dima, Oana; Lu, Fachuang; Van de Peer, Yves; Vanholme, Ruben; Ralph, John; Vanholme, Bartel; Boerjan, Wout

    2014-01-01

    Plant metabolomics is increasingly used for pathway discovery and to elucidate gene function. However, the main bottleneck is the identification of the detected compounds. This is more pronounced for secondary metabolites as many of their pathways are still underexplored. Here, an algorithm is presented in which liquid chromatography–mass spectrometry profiles are searched for pairs of peaks that have mass and retention time differences corresponding with those of substrates and products from well-known enzymatic reactions. Concatenating the latter peak pairs, called candidate substrate-product pairs (CSPP), into a network displays tentative (bio)synthetic routes. Starting from known peaks, propagating the network along these routes allows the characterization of adjacent peaks leading to their structure prediction. As a proof-of-principle, this high-throughput cheminformatics procedure was applied to the Arabidopsis thaliana leaf metabolome where it allowed the characterization of the structures of 60% of the profiled compounds. Moreover, based on searches in the Chemical Abstract Service database, the algorithm led to the characterization of 61 compounds that had never been described in plants before. The CSPP-based annotation was confirmed by independent MSn experiments. In addition to being high throughput, this method allows the annotation of low-abundance compounds that are otherwise not amenable to isolation and purification. This method will greatly advance the value of metabolomics in systems biology. PMID:24685999

  12. HA03 as an Iranian Candidate Concealed Antigen for Vaccination against Hyalomma anatolicum anatolicum: Comparative Structural and In silico Studies

    Directory of Open Access Journals (Sweden)

    Mohammadi, A.

    2013-12-01

    Full Text Available In the last decades researchers had focused on developing a vaccine against tick based on protective antigen. Recombinant vaccines based on concealed antigen from Boophilus microplus have been developed in Australia and Cuba by the name of TICKGARD and GAVAC (De La Fuente and Kocan, 2006. Further studies on this antigen have shown some extent of protection against other species (De Vos et al., 2001. In Iran most important species is Hyalomma anatolicum and limited information about its control are available. This paper reports structural and polymorphic analysis of HA03 as an Iranian candidate concealed antigen of H. a. anatolicum deposited in Gen-Bank .(Aghaeipour et al. GQ228820. The comparison between this antigen and other mid gut concealed antigen that their characteristics are available in GenBank showed there are high rate of similarity between them. The HA03 amino acid sequence had a homology of around 89%, 64%, 56% with HA98, BM86, BM95 respectively. Potential of MHC class I and II binding region indicated a considerable variation between BM86 antigen and its efficiency against Iranian H. a. anatolicum. In addition, predicted major of hydrophobisity and similarity in N-glycosylation besides large amount of cystein and seven EGF like regions presented in protein structure revealed that value of HA03 as a new protective antigen and the necessity of the development, BM86 homolog of H. a. anatolicum HA03 based recombinant vaccine.

  13. The dyslexia candidate locus on 2p12 is associated with general cognitive ability and white matter structure.

    Directory of Open Access Journals (Sweden)

    Thomas S Scerri

    Full Text Available Independent studies have shown that candidate genes for dyslexia and specific language impairment (SLI impact upon reading/language-specific traits in the general population. To further explore the effect of disorder-associated genes on cognitive functions, we investigated whether they play a role in broader cognitive traits. We tested a panel of dyslexia and SLI genetic risk factors for association with two measures of general cognitive abilities, or IQ, (verbal and non-verbal in the Avon Longitudinal Study of Parents and Children (ALSPAC cohort (N>5,000. Only the MRPL19/C2ORF3 locus showed statistically significant association (minimum P = 0.00009 which was further supported by independent replications following analysis in four other cohorts. In addition, a fifth independent sample showed association between the MRPL19/C2ORF3 locus and white matter structure in the posterior part of the corpus callosum and cingulum, connecting large parts of the cortex in the parietal, occipital and temporal lobes. These findings suggest that this locus, originally identified as being associated with dyslexia, is likely to harbour genetic variants associated with general cognitive abilities by influencing white matter structure in localised neuronal regions.

  14. A Logical Characterization of Iterated Admissibility

    CERN Document Server

    Halpern, Joseph Y

    2009-01-01

    Brandenburger, Friedenberg, and Keisler provide an epistemic characterization of iterated admissibility (i.e., iterated deletion of weakly dominated strategies) where uncertainty is represented using LPSs (lexicographic probability sequences). Their characterization holds in a rich structure called a complete structure, where all types are possible. Here, a logical charaacterization of iterated admisibility is given that involves only standard probability and holds in all structures, not just complete structures. A stronger notion of strong admissibility is then defined. Roughly speaking, strong admissibility is meant to capture the intuition that "all the agent knows" is that the other agents satisfy the appropriate rationality assumptions. Strong admissibility makes it possible to relate admissibility, canonical structures (as typically considered in completeness proofs in modal logic), complete structures, and the notion of ``all I know''.

  15. Approximate iterative algorithms

    CERN Document Server

    Almudevar, Anthony Louis

    2014-01-01

    Iterative algorithms often rely on approximate evaluation techniques, which may include statistical estimation, computer simulation or functional approximation. This volume presents methods for the study of approximate iterative algorithms, providing tools for the derivation of error bounds and convergence rates, and for the optimal design of such algorithms. Techniques of functional analysis are used to derive analytical relationships between approximation methods and convergence properties for general classes of algorithms. This work provides the necessary background in functional analysis a

  16. CORSICA modelling of ITER hybrid operation scenarios

    Science.gov (United States)

    Kim, S. H.; Bulmer, R. H.; Campbell, D. J.; Casper, T. A.; LoDestro, L. L.; Meyer, W. H.; Pearlstein, L. D.; Snipes, J. A.

    2016-12-01

    The hybrid operating mode observed in several tokamaks is characterized by further enhancement over the high plasma confinement (H-mode) associated with reduced magneto-hydro-dynamic (MHD) instabilities linked to a stationary flat safety factor (q ) profile in the core region. The proposed ITER hybrid operation is currently aiming at operating for a long burn duration (>1000 s) with a moderate fusion power multiplication factor, Q , of at least 5. This paper presents candidate ITER hybrid operation scenarios developed using a free-boundary transport modelling code, CORSICA, taking all relevant physics and engineering constraints into account. The ITER hybrid operation scenarios have been developed by tailoring the 15 MA baseline ITER inductive H-mode scenario. Accessible operation conditions for ITER hybrid operation and achievable range of plasma parameters have been investigated considering uncertainties on the plasma confinement and transport. ITER operation capability for avoiding the poloidal field coil current, field and force limits has been examined by applying different current ramp rates, flat-top plasma currents and densities, and pre-magnetization of the poloidal field coils. Various combinations of heating and current drive (H&CD) schemes have been applied to study several physics issues, such as the plasma current density profile tailoring, enhancement of the plasma energy confinement and fusion power generation. A parameterized edge pedestal model based on EPED1 added to the CORSICA code has been applied to hybrid operation scenarios. Finally, fully self-consistent free-boundary transport simulations have been performed to provide information on the poloidal field coil voltage demands and to study the controllability with the ITER controllers. Extended from Proc. 24th Int. Conf. on Fusion Energy (San Diego, 2012) IT/P1-13.

  17. Investigation of microstructure and mechanical properties of explosively welded ITER-grade 316L(N)/CuCrZr hollow structural member

    Energy Technology Data Exchange (ETDEWEB)

    Ma, Rui, E-mail: mr9980@163.com [PLA University of Science and Technology, Nanjing 210007 (China); Navy Command Academy, Nanjing 210007 (China); Wang, Yaohua [PLA University of Science and Technology, Nanjing 210007 (China); Wu, Jihong [Southwestern Institute of Physics, Chengdu 610041 (China); Duan, Mianjun [PLA University of Science and Technology, Nanjing 210007 (China)

    2015-04-15

    Highlights: • Develop a new explosive welding method to fabricate the hollow structural member. • Effects of solution annealing on microstructure of welding interface researched. • Influence of heat treatments on hardness evolution in welding interface studied. • The ultimate strength and elongation were increased after solution annealing. • The interface of samples was exhibited ductile fracture after solution annealing. - Abstract: In this study, a new explosive welding method furnished an effective way for manufacturing ITER-grade 316L(N) stainless steel/CuCrZr alloy hollow structural member. In order to recover some hardening effects, caused by plastic deformation during explosion welding in the materials bonding interface region, the welded samples were subject to the solution annealing (SA) treatment at 970 °C for 30 min. The SA heat-treated samples were then aged at 580 °C for 2 h. Optical microscopy (OM) and electron microscopy (SEM) were used to analyze the microstructure of bonding interface. Energy dispersive spectroscopy (EDS) analysis was performed to investigate the diffusion zone formed in the interface region after the solution annealing (SA) treatment. Moreover, the mechanical properties of the welded samples were evaluated through microhardness test and tensile strength test. Microstructural analysis showed that the welded sample had a wavy interface, and there was no melting zone and intermetallic layer formed in the interface. The result of microhardness test revealed an increase in hardness for both sides near to the bonding interface; this is due to more severe plastic deformation in these regions during the explosive welding. After the tensile test, obvious necking was observed in the fracture cross section of samples. SEM observation indicated that the samples with the post solution annealing treatment exhibited a ductile fracture with dimple features after tensile test.

  18. Structure, allelic diversity and selection of Asr genes, candidate for drought tolerance, in Oryza sativa L. and wild relatives.

    Science.gov (United States)

    Philippe, Romain; Courtois, Brigitte; McNally, Kenneth L; Mournet, Pierre; El-Malki, Redouane; Le Paslier, Marie Christine; Fabre, Denis; Billot, Claire; Brunel, Dominique; Glaszmann, Jean-Christophe; This, Dominique

    2010-08-01

    Asr (ABA, stress, ripening) genes represent a small gene family potentially involved in drought tolerance in several plant species. To analyze their interest for rice breeding for water-limited environments, this gene family was characterized further. Genomic organization of the gene family reveals six members located on four different chromosomes and with the same exon-intron structure. The maintenance of six members of the Asr gene family, which are the result of combination between tandem duplication and whole genome duplication, and their differential regulation under water stress, involves probably some sub-functionalization. The polymorphism of four members was studied in a worldwide collection of 204 accessions of Oryza sativa L. and 14 accessions of wild relatives (O. rufipogon and O. nivara). The nucleotide diversity of the Asr genes was globally low, but contrasted for the different genes, leading to different shapes of haplotype networks. Statistical tests for neutrality were used and compared to their distribution in a set of 111 reference genes spread across the genome, derived from another published study. Asr3 diversity exhibited a pattern concordant with a balancing selection at the species level and with a directional selection in the tropical japonica sub-group. This study provides a thorough description of the organization of the Asr family, and the nucleotide and haplotype diversity of four Asr in Oryza sativa species. Asr3 stood out as the best potential candidate. The polymorphism detected here represents a first step towards an association study between genetic polymorphisms of this gene family and variation in drought tolerance traits.

  19. Robust iterative methods

    Energy Technology Data Exchange (ETDEWEB)

    Saadd, Y.

    1994-12-31

    In spite of the tremendous progress achieved in recent years in the general area of iterative solution techniques, there are still a few obstacles to the acceptance of iterative methods in a number of applications. These applications give rise to very indefinite or highly ill-conditioned non Hermitian matrices. Trying to solve these systems with the simple-minded standard preconditioned Krylov subspace methods can be a frustrating experience. With the mathematical and physical models becoming more sophisticated, the typical linear systems which we encounter today are far more difficult to solve than those of just a few years ago. This trend is likely to accentuate. This workshop will discuss (1) these applications and the types of problems that they give rise to; and (2) recent progress in solving these problems with iterative methods. The workshop will end with a hopefully stimulating panel discussion with the speakers.

  20. Full Dynamic Analysis of Mooring Solution Candidates - First Iteration

    DEFF Research Database (Denmark)

    Thomsen, Jonas Bjerg; Ferri, Francesco

    This report covers an initial full dynamic analysis of the mooring solutions for the four wave energy converters in the project “Mooring Solutions for Large Wave Energy Converters”. The analysis tends to provide the first understanding of the layouts and provide discussion on what parameters that...

  1. Extensive characterisation of advanced manufacturing solutions for the ITER Central Solenoid pre-compression system

    CERN Document Server

    Langeslag, S.A.E.; Libeyre, P.; Marcinek, D.J.; Zhang, Z.

    2015-01-01

    The ITER Central Solenoid (CS), positioned in the center of the ITER tokamak, will provide a magnetic field, contributing to the confinement of the plasma. The 13 m high CS consists of a vertical stack of 6 independently driven modules, dynamically activated. Resulting opposing currents can lead to high separation forces. A pre-compression structure is implemented to counteract these opposing forces, by realising a continuous 180 MN coil-to-coil contact loading. Preload is applied by mechanical fastening via 9 subunits, positioned along the coil stack, each consisting of 2 outer and 1 inner tie plate. The tie plates therefore need to feature outstanding mechanical behaviour in a large temperature range. High strength, Nitronic®-50 type F XM-19 austenitic stainless steel is selected as candidate material. The linearised stress distribution reaches approximately 250 MPa, leading to a required yield strength of 380 MPa at room temperature. Two different manufacturing methods are being studied for the procuremen...

  2. Melt damage simulation of W-macrobrush and divertor gaps after multiple transient events in ITER

    Energy Technology Data Exchange (ETDEWEB)

    Bazylev, B.N. [Forschungszentrum Karlsruhe, IHM, P.O. Box 3640, 76021 Karlsruhe (Germany)]. E-mail: bazylev@ihm.fzk.de; Janeschitz, G. [Forschungszentrum Karlsruhe, Fusion, P.O. Box 3640, 76021 Karlsruhe (Germany); Landman, I.S. [Forschungszentrum Karlsruhe, IHM, P.O. Box 3640, 76021 Karlsruhe (Germany); Loarte, A. [EFDA-CSU, Max-Planck-Institut fuer Plasmaphysik, D-85748 Garching (Germany); Pestchanyi, S.E. [Forschungszentrum Karlsruhe, IHM, P.O. Box 3640, 76021 Karlsruhe (Germany)

    2007-06-15

    Tungsten in the form of macrobrush structure is foreseen as one of two candidate materials for the ITER divertor and dome. In ITER, even for moderate and weak ELMs when a thin shielding layer does not protect the armour surface from the dumped plasma, the main mechanisms of metallic target damage remain surface melting and melt motion erosion, which determines the lifetime of the plasma facing components. The melt erosion of W-macrobrush targets with different geometry of brush surface under the heat loads caused by weak ELMs is numerically investigated using the modified code MEMOS. The optimal angle of brush surface inclination that provides a minimum of surface roughness is estimated for given inclination angles of impacting plasma stream and given parameters of the macrobrush target. For multiple disruptions the damage of the dome gaps and the gaps between divertor cassettes caused by the radiation impact is estimated.

  3. Melt damage simulation of W-macrobrush and divertor gaps after multiple transient events in ITER

    Science.gov (United States)

    Bazylev, B. N.; Janeschitz, G.; Landman, I. S.; Loarte, A.; Pestchanyi, S. E.

    2007-06-01

    Tungsten in the form of macrobrush structure is foreseen as one of two candidate materials for the ITER divertor and dome. In ITER, even for moderate and weak ELMs when a thin shielding layer does not protect the armour surface from the dumped plasma, the main mechanisms of metallic target damage remain surface melting and melt motion erosion, which determines the lifetime of the plasma facing components. The melt erosion of W-macrobrush targets with different geometry of brush surface under the heat loads caused by weak ELMs is numerically investigated using the modified code MEMOS. The optimal angle of brush surface inclination that provides a minimum of surface roughness is estimated for given inclination angles of impacting plasma stream and given parameters of the macrobrush target. For multiple disruptions the damage of the dome gaps and the gaps between divertor cassettes caused by the radiation impact is estimated.

  4. Iterative List Decoding

    DEFF Research Database (Denmark)

    Justesen, Jørn; Høholdt, Tom; Hjaltason, Johan

    2005-01-01

    We analyze the relation between iterative decoding and the extended parity check matrix. By considering a modified version of bit flipping, which produces a list of decoded words, we derive several relations between decodable error patterns and the parameters of the code. By developing a tree...... of codewords at minimal distance from the received vector, we also obtain new information about the code....

  5. Iterative software kernels

    Energy Technology Data Exchange (ETDEWEB)

    Duff, I.

    1994-12-31

    This workshop focuses on kernels for iterative software packages. Specifically, the three speakers discuss various aspects of sparse BLAS kernels. Their topics are: `Current status of user lever sparse BLAS`; Current status of the sparse BLAS toolkit`; and `Adding matrix-matrix and matrix-matrix-matrix multiply to the sparse BLAS toolkit`.

  6. "Why Are You Doing This?" Questions on Purpose, Structure, and Outcomes in Participatory Action Research Engaging Youth and Teacher Candidates

    Science.gov (United States)

    Galletta, Anne; Jones, Vanessa

    2010-01-01

    Our article is based on a study of our integration of social foundations coursework with filmmaking and participatory action research, bringing teacher candidates and middle and high school students together. The project was carried out in partnership between an urban university and two nearby public schools within a Midwestern city known for high…

  7. Studying uniform thickness II: Transversely nonsimple iterated torus knots

    DEFF Research Database (Denmark)

    LaFountain, Douglas

    2011-01-01

    We prove that an iterated torus knot type in the standard contact 3-sphere fails the uniform thickness property (UTP) if and only if it is formed from repeated positive cablings, which is precisely when an iterated torus knot supports the standard contact structure. This is the first complete UTP...... classification for a large class of knots. We also show that all iterated torus knots that fail the UTP support cabling knot types that are transversely non-simple....

  8. Testing of the OMERACT 8 draft validation criteria for a soluble biomarker reflecting structural damage in rheumatoid arthritis: a systematic literature search on 5 candidate biomarkers

    DEFF Research Database (Denmark)

    Syversen, Silje W; Landewe, Robert; van der Heijde, Désirée;

    2009-01-01

    OBJECTIVE: To test the OMERACT 8 draft validation criteria for soluble biomarkers by assessing the strength of literature evidence in support of 5 candidate biomarkers. METHODS: A systematic literature search was conducted on the 5 soluble biomarkers RANKL, osteoprotegerin (OPG), matrix...... metalloprotease (MMP-3), urine C-telopeptide of types I and II collagen (U-CTX-I and U CTX-II), focusing on the 14 OMERACT 8 criteria. Two electronic voting exercises were conducted to address: (1) strength of evidence for each biomarker as reflecting structural damage according to each individual criterion...... and the importance of each individual criterion; (2) overall strength of evidence in support of each of the 5 candidate biomarkers as reflecting structural damage endpoints in rheumatoid arthritis (RA) and identification of omissions to the criteria set. RESULTS: The search identified 111 articles. The strength...

  9. Iterative Algorithms for Nonexpansive Mappings

    Directory of Open Access Journals (Sweden)

    Yao Yonghong

    2008-01-01

    Full Text Available Abstract We suggest and analyze two new iterative algorithms for a nonexpansive mapping in Banach spaces. We prove that the proposed iterative algorithms converge strongly to some fixed point of .

  10. Isolation, characterization, and structure analysis of a non-TIR-NBS-LRR encoding candidate gene from MYMIV-resistant Vigna mungo.

    Science.gov (United States)

    Maiti, Soumitra; Paul, Sujay; Pal, Amita

    2012-11-01

    Yellow mosaic disease of Vigna mungo caused by Mungbean yellow mosaic India virus (MYMIV) is still a major threat in the crop production. A candidate disease resistance (R) gene, CYR1 that co-segregates with MYMIV-resistant populations of V. mungo has been isolated. CYR1 coded in silico translated protein sequence comprised of 1,176 amino acids with coiled coil structure at the N-terminus, central nucleotide binding site (NBS) and C-terminal leucine-rich repeats (LRR) that belongs to non-TIR-NBS-LRR subfamily of plant R genes. CYR1 transcript was unambiguously expressed during incompatible plant virus interactions. A putative promoter-like sequence present upstream of this candidate gene perhaps regulates its expression. Enhanced transcript level upon MYMIV infection suggests involvement of this candidate gene in conferring resistance against the virus. In silico constructed 3D models of NBS and LRR regions of this candidate protein and MYMIV-coat protein (CP) revealed that CYR1-LRR forms an active pocket and successively interacts with MYMIV-CP during docking, like that of receptor-ligand interaction; indicating a critical role of CYR1 as signalling molecule to protect V. mungo plants from MYMIV. This suggests involvement of CYR1 in recognizing MYMIV-effector molecule thus contributing to incompatible interaction. This study is the first stride to understand molecular mechanism of MYMIV resistance.

  11. Iterative supervirtual refraction interferometry

    KAUST Repository

    Al-Hagan, Ola

    2014-05-02

    In refraction tomography, the low signal-to-noise ratio (S/N) can be a major obstacle in picking the first-break arrivals at the far-offset receivers. To increase the S/N, we evaluated iterative supervirtual refraction interferometry (ISVI), which is an extension of the supervirtual refraction interferometry method. In this method, supervirtual traces are computed and then iteratively reused to generate supervirtual traces with a higher S/N. Our empirical results with both synthetic and field data revealed that ISVI can significantly boost up the S/N of far-offset traces. The drawback is that using refraction events from more than one refractor can introduce unacceptable artifacts into the final traveltime versus offset curve. This problem can be avoided by careful windowing of refraction events.

  12. Iterative participatory design

    DEFF Research Database (Denmark)

    Simonsen, Jesper; Hertzum, Morten

    2010-01-01

    iterative process of mutual learning by designers and domain experts (users), who aim to change the users’ work practices through the introduction of information systems. We provide an illustrative case example with an ethnographic study of clinicians experimenting with a new electronic patient record......The theoretical background in this chapter is information systems development in an organizational context. This includes theories from participatory design, human-computer interaction, and ethnographically inspired studies of work practices. The concept of design is defined as an experimental...... system, focussing on emergent and opportunity-based change enabled by appropriating the system into real work. The contribution to a general core of design research is a reconstruction of the iterative prototyping approach into a general model for sustained participatory design....

  13. The Iterate Manual

    Science.gov (United States)

    1990-10-01

    is probably a bad idea. A better versica would use a temporary: (defmacro sum-of-squares (expr) (let ((temp ( gensym ))) ’(lot (,temp ,expr)) (sum...val ( gensym )) (tempi ( gensym )) (temp2 ( gensym )) (winner (or var iterate::*result-var*))) ’(progn (with ,max-val - nil) (with ,winner = nil) (cond ((null...the elements of a vector (disregards fill-pointer)" (let ((vect ( gensym )) (end ( gensym )) (index ( gensym ))) ’(progn (with ,vect - v) (with ,end = (array

  14. Double layer structure-based virtual screening reveals 3'-Hydroxy-A-Naphthoflavone as novel inhibitor candidate of human acetylcholinesterase

    Science.gov (United States)

    Ichsan, Mochammad; Pangastuti, Ardini; Habibi, Mohammad Wildan; Juliana, Kartika

    2016-03-01

    One of the most effective target for Alzheimer's disease's (AD) treatment is the inhibition of human acetylcholinesterase (hAChE) eventhough it has many side effects. So that, this study was aimed to discover a new candidate of hAChE's inhibitor that has more negative binding affinity than existing drugs. hAChE's 3D model used in this study has a good quality according to its number of residues in most favoured regions (92%), three bad contacts, >50 ERRAT's score (85,870) and successfully passed the VERIFY 3D threshold (>80%). Based on the first layer of SBVS againts more than 12.180.630 ligands, we discovered 11.806 hits and then we found 359 hits from the second layer of SBVS. Based on our previous steps, we found that 3'-Hydroxy-a-Naphthoflavone was the only one candidate, that directly interacted with Trp286 via hydrogen bond and hydrophobic interactions and also has the most negative binding affinity (-10,6 kcal/mol) and also has more negative than existing hAChE's inhibitors, such as tacrine, donepezil, etc. 3'-Hydroxy-a-Naphthoflavone is the best candidate of hAChE's inhibitor based on its binding affinity (-10,6 kcal/mol) that is more negative than existing hAChE's inhibitors, such as tacrine, donepezil, etc.

  15. It was the demonstration of industrial steel production capacity ferritic-martensitic Spanish ASTURFER scale demand ITER; Hacia la demostracion de capacidad de produccion industrial del acero ferritico-martensitico espanol ASTURFER a escala de demanda ITER

    Energy Technology Data Exchange (ETDEWEB)

    Coto, R.; Serrano, M.; Moran, A.; Rodriguez, D.; Artimez, J. A.; Belzunce, J.; Sedano, L.

    2013-07-01

    Reduced Activation Ferritic-Martensitic (RAFM) structural steels are considered as candidate materials with notable possibilities to be incorporated to fusion reactor ITER, nowadays under construction, and future fusion reactor DEMO, involving a notable forecasting of supply materials, with a considerable limitation due to the few number of furnishes currently on the market. The manufacture at an industrial scale of the ASTURFER steel, developed at laboratory scale by ITMA Materials Technology and the Structural Materials Division of the Technology Division of CIEMAT would be a significant business opportunity for steelwork companies.

  16. iHadoop: Asynchronous Iterations Support for MapReduce

    KAUST Repository

    Elnikety, Eslam

    2011-08-01

    MapReduce is a distributed programming framework designed to ease the development of scalable data-intensive applications for large clusters of commodity machines. Most machine learning and data mining applications involve iterative computations over large datasets, such as the Web hyperlink structures and social network graphs. Yet, the MapReduce model does not efficiently support this important class of applications. The architecture of MapReduce, most critically its dataflow techniques and task scheduling, is completely unaware of the nature of iterative applications; tasks are scheduled according to a policy that optimizes the execution for a single iteration which wastes bandwidth, I/O, and CPU cycles when compared with an optimal execution for a consecutive set of iterations. This work presents iHadoop, a modified MapReduce model, and an associated implementation, optimized for iterative computations. The iHadoop model schedules iterations asynchronously. It connects the output of one iteration to the next, allowing both to process their data concurrently. iHadoop\\'s task scheduler exploits inter- iteration data locality by scheduling tasks that exhibit a producer/consumer relation on the same physical machine allowing a fast local data transfer. For those iterative applications that require satisfying certain criteria before termination, iHadoop runs the check concurrently during the execution of the subsequent iteration to further reduce the application\\'s latency. This thesis also describes our implementation of the iHadoop model, and evaluates its performance against Hadoop, the widely used open source implementation of MapReduce. Experiments using different data analysis applications over real-world and synthetic datasets show that iHadoop performs better than Hadoop for iterative algorithms, reducing execution time of iterative applications by 25% on average. Furthermore, integrating iHadoop with HaLoop, a variant Hadoop implementation that caches

  17. Iterated learning and the evolution of language.

    Science.gov (United States)

    Kirby, Simon; Griffiths, Tom; Smith, Kenny

    2014-10-01

    Iterated learning describes the process whereby an individual learns their behaviour by exposure to another individual's behaviour, who themselves learnt it in the same way. It can be seen as a key mechanism of cultural evolution. We review various methods for understanding how behaviour is shaped by the iterated learning process: computational agent-based simulations; mathematical modelling; and laboratory experiments in humans and non-human animals. We show how this framework has been used to explain the origins of structure in language, and argue that cultural evolution must be considered alongside biological evolution in explanations of language origins. Copyright © 2014 Elsevier Ltd. All rights reserved.

  18. Studying uniform thickness II: Transversely nonsimple iterated torus knots

    DEFF Research Database (Denmark)

    LaFountain, Douglas

    2011-01-01

    We prove that an iterated torus knot type in the standard contact 3-sphere fails the uniform thickness property (UTP) if and only if it is formed from repeated positive cablings, which is precisely when an iterated torus knot supports the standard contact structure. This is the first complete UTP...

  19. Magnet design technical report---ITER definition phase

    Energy Technology Data Exchange (ETDEWEB)

    Henning, C. (ed.)

    1989-04-28

    This report contains papers on the following topics: conceptual design; radiation damage of ITER magnet systems; insulation system of the magnets; critical current density and strain sensitivity; toroidal field coil structural analysis; stress analysis for the ITER central solenoid; and volt-second capabilities and PF magnet configurations.

  20. ERGODIC THEOREM FOR INFINITE ITERATED FUNCTION SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    O Hyong-chol; Ro Yong-hwa; Kil Won-gun

    2005-01-01

    A set of contraction maps of a metric space is called an iterated function systems.Iterated function systems with condensation can be considered infinite iterated function systems. Infinite iterated function systems on compact metric spaces were studied. Using the properties of Banach limit and uniform contractiveness, it was proved that the random iterating algorithms for infinite iterated function systems on compact metric spaces satisfy ergodicity. So the random iterating algorithms for iterated function systems with condensation satisfy ergodicity, too.

  1. Computation of correlation matrices for tetraquark candidates with $J^P = 0^+$ and flavor structure $q_1 \\bar{q_2} q_3 \\bar{q}_3$

    CERN Document Server

    Berlin, Joshua; Alexandrou, Constantia; Brida, Mattia Dalla; Gravina, Mario; Wagner, Marc

    2015-01-01

    The conjecture that several recently observed mesons have a structure, which is not dominated by an ordinary quark-antiquark pair, but by a four-quark structure, is being actively investigated both theoretical and experimentally. Such a state may be characterized as a mesonic molecule or as a diquark-antidiquark pair. Lattice QCD provides a theoretically sound framework to study such states. To quantitatively investigate the internal structure of such mesons, one needs to precisely compute correlation matrices containing several interpolating operators including two and four quarks. Here we discuss certain technical aspects of such correlation matrices suited to study tetraquark candidates with $J^P = 0^+$ and flavor structure $q_1 \\bar{q_2} q_3 \\bar{q}_3$, e.g.\\ the $a_0(980)$ meson, the $D_{s0}^\\ast$ meson and some of the charged $c \\bar{c}$ $X$ states. Some numerical results for the $a_0(980)$ meson are presented.

  2. Requirements for ITER diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Young, K.M.

    1991-01-01

    The development and design of plasma diagnostics for the International Thermonuclear Experimental Reactor (ITER) present a formidable challenge for experimental plasma physicists. The large plasma size, the high central density and temperature and the very high thermal wall loadings provide new challenges for present measurement techniques and lead to a search for new methods. But the physics and control requirements for the long burn phase of the discharge, combined with very limited access to the plasma, constrained by the requirement for radiation shielding of the coils and sharing of access ports with heating and current drive power, remote manipulation, fueling and turn blanket modules, make for very difficult design choices. An initial attempt at these choices has been made by an international team of diagnostic physicists, gathering together in a series of three workshops during the ITER Conceptual Design Activity. This paper is based on that report and provides a summary of its most important points. To provide a background against which to place the diagnostic requirements and design concepts, the ITER device, its most important plasma properties and the proposed experimental program will be described. The specifications for the measurement of the plasma parameters and the proposed diagnostics for these measurements will then be addressed, followed by some examples of the design concepts that have been proposed. As a result of these design studies, it was clear that there were many uncertainties associated with these concepts, particularly because of the nuclear radiation environment, so that a Research and Development Program for diagnostic hardware was established. It will also be briefly summarized.

  3. Runaway electrons and ITER

    Science.gov (United States)

    Boozer, Allen H.

    2017-05-01

    The potential for damage, the magnitude of the extrapolation, and the importance of the atypical—incidents that occur once in a thousand shots—make theory and simulation essential for ensuring that relativistic runaway electrons will not prevent ITER from achieving its mission. Most of the theoretical literature on electron runaway assumes magnetic surfaces exist. ITER planning for the avoidance of halo and runaway currents is focused on massive-gas or shattered-pellet injection of impurities. In simulations of experiments, such injections lead to a rapid large-scale magnetic-surface breakup. Surface breakup, which is a magnetic reconnection, can occur on a quasi-ideal Alfvénic time scale when the resistance is sufficiently small. Nevertheless, the removal of the bulk of the poloidal flux, as in halo-current mitigation, is on a resistive time scale. The acceleration of electrons to relativistic energies requires the confinement of some tubes of magnetic flux within the plasma and a resistive time scale. The interpretation of experiments on existing tokamaks and their extrapolation to ITER should carefully distinguish confined versus unconfined magnetic field lines and quasi-ideal versus resistive evolution. The separation of quasi-ideal from resistive evolution is extremely challenging numerically, but is greatly simplified by constraints of Maxwell’s equations, and in particular those associated with magnetic helicity. The physics of electron runaway along confined magnetic field lines is clarified by relations among the poloidal flux change required for an e-fold in the number of electrons, the energy distribution of the relativistic electrons, and the number of relativistic electron strikes that can be expected in a single disruption event.

  4. Iterative participatory design

    DEFF Research Database (Denmark)

    2010-01-01

    The theoretical background in this chapter is information systems development in an organizational context. This includes theories from participatory design, human-computer interaction, and ethnographically inspired studies of work practices. The concept of design is defined as an experimental...... iterative process of mutual learning by designers and domain experts (users), who aim to change the users’ work practices through the introduction of information systems. We provide an illustrative case example with an ethnographic study of clinicians experimenting with a new electronic patient record...

  5. Iterative Magnetometer Calibration

    Science.gov (United States)

    Sedlak, Joseph

    2006-01-01

    This paper presents an iterative method for three-axis magnetometer (TAM) calibration that makes use of three existing utilities recently incorporated into the attitude ground support system used at NASA's Goddard Space Flight Center. The method combines attitude-independent and attitude-dependent calibration algorithms with a new spinning spacecraft Kalman filter to solve for biases, scale factors, nonorthogonal corrections to the alignment, and the orthogonal sensor alignment. The method is particularly well-suited to spin-stabilized spacecraft, but may also be useful for three-axis stabilized missions given sufficient data to provide observability.

  6. ITER LIDAR performance analysis.

    Science.gov (United States)

    Beurskens, M N A; Giudicotti, L; Kempenaars, M; Scannell, R; Walsh, M J

    2008-10-01

    The core LIDAR Thomson scattering for ITER is specified for core profile measurements with a spatial resolution of 7 cm (a/30) for the range of 500 eV3x10(19) m(-3) at an accuracy of system can meet its spatial and accuracy specifications for higher temperatures of T(e)>5 keV with a combination of a neodymium-doped yttrium aluminum garnet (Nd:YAG) laser (lambda(0)=1064 nm, Delta lambdanear infrared detectors.

  7. The method used to set the pass mark in an objective structured clinical examination defines the performance of candidates for certification as rheumatologists.

    Science.gov (United States)

    Pascual-Ramos, Virginia; Guilaisne Bernard-Medina, Ana; Flores-Alvarado, Diana Elsa; Portela-Hernández, Margarita; Maldonado-Velázquez, María Del Rocío; Jara-Quezada, Luis Javier; Amezcua-Guerra, Luis Manuel; Rubio-Judith López-Zepeda, Nadina E; Álvarez-Hernandez, Everardo; Saavedra, Miguel Ángel; Arce-Salinas, César Alejandro

    2017-02-01

    The Mexican Accreditation Council for Rheumatology certifies trainees (TR) on an annual basis using both a multiple-choice question (MCQ) test and an objective structured clinical examination (OSCE). For 2013 and 2014, the OSCE pass mark (PM) was set by criterion referencing as ≥6 (CPM), whereas overall rating of borderline performance method (BPM) was added for 2015 and 2016 accreditations. We compared OSCE TR performance according to CPM and BPM, and examined whether correlations between MCQ and OSCE were affected by PM. Forty-three (2015) and 37 (2016) candidates underwent both tests. Altogether, OSCE were integrated by 15 validated stations; one evaluator per station scored TR performance according to a station-tailored check-list and a Likert scale (fail, borderline, above range) of overall performance. A composite OSCE score was derived for each candidate. Appropriate statistics were used. Mean (±standard derivation [SD]) MCQ test scores were 6.6±0.6 (2015) and 6.4±0.6 (2016) with 5 candidates receiving a failing score each year. Mean (±SD) OSCE scores were 7.4±0.6 (2015) and 7.3±0.6 (2016); no candidate received a failing CPM score in either 2015 or 2016 OSCE, although 21 (49%) and 19 (51%) TR, respectively, received a failing BPM score (calculated as 7.3 and 7.4, respectively). Stations for BPM ranged from 4.5 to 9.5; overall, candidates showed better performance in CPM. In all, MCQ correlated with composite OSCE, r=0.67 (2015) and r=0.53 (2016); P≤.001. Trainees with a passing BPM score in OSCE had higher MCQ scores than those with a failing score. Overall, OSCE-PM selection impacted candidates' performance but had a limited affect on correlation between clinical and practical examinations. Copyright © 2016 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología. All rights reserved.

  8. Iterative guided image fusion

    Directory of Open Access Journals (Sweden)

    Alexander Toet

    2016-08-01

    Full Text Available We propose a multi-scale image fusion scheme based on guided filtering. Guided filtering can effectively reduce noise while preserving detail boundaries. When applied in an iterative mode, guided filtering selectively eliminates small scale details while restoring larger scale edges. The proposed multi-scale image fusion scheme achieves spatial consistency by using guided filtering both at the decomposition and at the recombination stage of the multi-scale fusion process. First, size-selective iterative guided filtering is applied to decompose the source images into approximation and residual layers at multiple spatial scales. Then, frequency-tuned filtering is used to compute saliency maps at successive spatial scales. Next, at each spatial scale binary weighting maps are obtained as the pixelwise maximum of corresponding source saliency maps. Guided filtering of the binary weighting maps with their corresponding source images as guidance images serves to reduce noise and to restore spatial consistency. The final fused image is obtained as the weighted recombination of the individual residual layers and the mean of the approximation layers at the coarsest spatial scale. Application to multiband visual (intensified and thermal infrared imagery demonstrates that the proposed method obtains state-of-the-art performance for the fusion of multispectral nightvision images. The method has a simple implementation and is computationally efficient.

  9. Runaway electrons and ITER

    Science.gov (United States)

    Boozer, Allen

    2016-10-01

    ITER planning for avoiding runaway damage depends on magnetic surface breakup in fast relaxations. These arise in thermal quenches and in the spreading of impurities from massive gas injection or shattered pellets. Surface breakup would prevent a runaway to relativistic energies were it not for non-intercepting flux tubes, which contain magnetic field lines that do not intercept the walls. Such tubes persist near the magnetic axis and in the cores of islands but must dissipate before any confining surfaces re-form. Otherwise, a highly dangerous situation arises. Electrons that were trapped and accelerated in these flux tubes can fill a large volume of stochastic field lines and serve as a seed for the transfer of the full plasma current to runaways. If the outer confining surfaces are punctured, as by a drift into the wall, then the full runaway inventory will be lost in a short pulse along a narrow flux tube. Although not part of ITER planning, currents induced in the walls by the fast magnetic relaxation could be used to passively prevent outer surfaces re-forming. If magnetic surface breakup can be avoided during impurity injection, the plasma current could be terminated in tens of milliseconds by plasma cooling with no danger of runaway. Support by DoE Office of Fusion Energy Science Grant De-FG02-03ER54696.

  10. ITER helium ash accumulation

    Energy Technology Data Exchange (ETDEWEB)

    Hogan, J.T.; Hillis, D.L.; Galambos, J.; Uckan, N.A. (Oak Ridge National Lab., TN (USA)); Dippel, K.H.; Finken, K.H. (Forschungszentrum Juelich GmbH (Germany, F.R.). Inst. fuer Plasmaphysik); Hulse, R.A.; Budny, R.V. (Princeton Univ., NJ (USA). Plasma Physics Lab.)

    1990-01-01

    Many studies have shown the importance of the ratio {upsilon}{sub He}/{upsilon}{sub E} in determining the level of He ash accumulation in future reactor systems. Results of the first tokamak He removal experiments have been analysed, and a first estimate of the ratio {upsilon}{sub He}/{upsilon}{sub E} to be expected for future reactor systems has been made. The experiments were carried out for neutral beam heated plasmas in the TEXTOR tokamak, at KFA/Julich. Helium was injected both as a short puff and continuously, and subsequently extracted with the Advanced Limiter Test-II pump limiter. The rate at which the He density decays has been determined with absolutely calibrated charge exchange spectroscopy, and compared with theoretical models, using the Multiple Impurity Species Transport (MIST) code. An analysis of energy confinement has been made with PPPL TRANSP code, to distinguish beam from thermal confinement, especially for low density cases. The ALT-II pump limiter system is found to exhaust the He with maximum exhaust efficiency (8 pumps) of {approximately}8%. We find 1<{upsilon}{sub He}/{upsilon}{sub E}<3.3 for the database of cases analysed to date. Analysis with the ITER TETRA systems code shows that these values would be adequate to achieve the required He concentration with the present ITER divertor He extraction system.

  11. Fusion neutron diagnostics on ITER tokamak

    Science.gov (United States)

    Bertalot, L.; Barnsley, R.; Direz, M. F.; Drevon, J. M.; Encheva, A.; Jakhar, S.; Kashchuk, Y.; Patel, K. M.; Arumugam, A. P.; Udintsev, V.; Walker, C.; Walsh, M.

    2012-04-01

    ITER is an experimental nuclear reactor, aiming to demonstrate the feasibility of nuclear fusion realization in order to use it as a new source of energy. ITER is a plasma device (tokamak type) which will be equipped with a set of plasma diagnostic tools to satisfy three key requirements: machine protection, plasma control and physics studies by measuring about 100 different parameters. ITER diagnostic equipment is integrated in several ports at upper, equatorial and divertor levels as well internally in many vacuum vessel locations. The Diagnostic Systems will be procured from ITER Members (Japan, Russia, India, United States, Japan, Korea and European Union) mainly with the supporting structures in the ports. The various diagnostics will be challenged by high nuclear radiation and electromagnetic fields as well by severe environmental conditions (ultra high vacuum, high thermal loads). Several neutron systems with different sensitivities are foreseen to measure ITER expected neutron emission from 1014 up to almost 1021 n/s. The measurement of total neutron emissivity is performed by means of Neutron Flux Monitors (NFM) installed in diagnostic ports and by Divertor Neutron Flux Monitors (DNFM) plus MicroFission Chambers (MFC) located inside the vacuum vessel. The neutron emission profile is measured with radial and vertical neutron cameras. Spectroscopy is accomplished with spectrometers looking particularly at 2.5 and 14 MeV neutron energy. Neutron Activation System (NAS), with irradiation ends inside the vacuum vessel, provide neutron yield data. A calibration strategy of the neutron diagnostics has been developed foreseeing in situ and cross calibration campaigns. An overview of ITER neutron diagnostic systems and of the associated challenging engineering and integration issues will be reported.

  12. Iterated crowdsourcing dilemma game

    Science.gov (United States)

    Oishi, Koji; Cebrian, Manuel; Abeliuk, Andres; Masuda, Naoki

    2014-02-01

    The Internet has enabled the emergence of collective problem solving, also known as crowdsourcing, as a viable option for solving complex tasks. However, the openness of crowdsourcing presents a challenge because solutions obtained by it can be sabotaged, stolen, and manipulated at a low cost for the attacker. We extend a previously proposed crowdsourcing dilemma game to an iterated game to address this question. We enumerate pure evolutionarily stable strategies within the class of so-called reactive strategies, i.e., those depending on the last action of the opponent. Among the 4096 possible reactive strategies, we find 16 strategies each of which is stable in some parameter regions. Repeated encounters of the players can improve social welfare when the damage inflicted by an attack and the cost of attack are both small. Under the current framework, repeated interactions do not really ameliorate the crowdsourcing dilemma in a majority of the parameter space.

  13. ITER Safety Analyses with ISAS

    Science.gov (United States)

    Gulden, W.; Nisan, S.; Porfiri, M.-T.; Toumi, I.; de Gramont, T. Boubée

    1997-06-01

    Detailed analyses of accident sequences for the International Thermonuclear Experimental Reactor (ITER), from an initiating event to the environmental release of activity, have involved in the past the use of different types of computer codes in a sequential manner. Since these codes were developed at different time scales in different countries, there is no common computing structure to enable automatic data transfer from one code to the other, and no possibility exists to model or to quantify the effect of coupled physical phenomena. To solve this problem, the Integrated Safety Analysis System of codes (ISAS) is being developed, which allows users to integrate existing computer codes in a coherent manner. This approach is based on the utilization of a command language (GIBIANE) acting as a “glue” to integrate the various codes as modules of a common environment. The present version of ISAS allows comprehensive (coupled) calculations of a chain of codes such as ATHENA (thermal-hydraulic analysis of transients and accidents), INTRA (analysis of in-vessel chemical reactions, pressure built-up, and distribution of reaction products inside the vacuum vessel and adjacent rooms), and NAUA (transport of radiological species within buildings and to the environment). In the near future, the integration of S AFALY (simultaneous analysis of plasma dynamics and thermal behavior of in-vessel components) is also foreseen. The paper briefly describes the essential features of ISAS development and the associated software architecture. It gives first results of a typical ITER accident sequence, a loss of coolant accident (LOCA) in the divertor cooling loop inside the vacuum vessel, amply demonstrating ISAS capabilities.

  14. An iterative decoupling solution method for large scale Lyapunov equations

    Science.gov (United States)

    Athay, T. M.; Sandell, N. R., Jr.

    1976-01-01

    A great deal of attention has been given to the numerical solution of the Lyapunov equation. A useful classification of the variety of solution techniques are the groupings of direct, transformation, and iterative methods. The paper summarizes those methods that are at least partly favorable numerically, giving special attention to two criteria: exploitation of a general sparse system matrix structure and efficiency in resolving the governing linear matrix equation for different matrices. An iterative decoupling solution method is proposed as a promising approach for solving large-scale Lyapunov equation when the system matrix exhibits a general sparse structure. A Fortran computer program that realizes the iterative decoupling algorithm is also discussed.

  15. Preliminary Design and Analysis of ITER In-Wall Shielding

    Institute of Scientific and Technical Information of China (English)

    LIU Changle; YU Jie; WU Songtao; CAI Yingxiang; PAN Wanjiang

    2007-01-01

    ITER in-wall shielding (IIS) is situated between the doubled shells of the ITER Vacuum Vessel (IVV). Its main functions are applied in shielding neutron, gamma-ray and toroidal field ripple reduction. The structure of IIS has been modelled according to the IVV design criteria which has been updated by the ITER team (IT). Static analysis and thermal expansion analysis were performed for the structure. Thermal-hydraulic analysis verified the heat removal capability and resulting temperature, pressure, and velocity changes in the coolant flow. Consequently, our design work is possibly suitable as a reference for IT's updated or final design in its next step.

  16. An iterative decoupling solution method for large scale Lyapunov equations

    Science.gov (United States)

    Athay, T. M.; Sandell, N. R., Jr.

    1976-01-01

    A great deal of attention has been given to the numerical solution of the Lyapunov equation. A useful classification of the variety of solution techniques are the groupings of direct, transformation, and iterative methods. The paper summarizes those methods that are at least partly favorable numerically, giving special attention to two criteria: exploitation of a general sparse system matrix structure and efficiency in resolving the governing linear matrix equation for different matrices. An iterative decoupling solution method is proposed as a promising approach for solving large-scale Lyapunov equation when the system matrix exhibits a general sparse structure. A Fortran computer program that realizes the iterative decoupling algorithm is also discussed.

  17. Quantitative Structure-Use Relationship Model thresholds for Model Validation, Domain of Applicability, and Candidate Alternative Selection

    Data.gov (United States)

    U.S. Environmental Protection Agency — This file contains value of the model training set confusion matrix, domain of applicability evaluation based on training set to predicted chemicals structural...

  18. Structural stability at high pressure, electronic, and magnetic properties of BaFZnAs: A new candidate of host material of diluted magnetic semiconductors

    Science.gov (United States)

    Bi-Juan, Chen; Zheng, Deng; Xian-Cheng, Wang; Shao-Min, Feng; Zhen, Yuan; Si-Jia, Zhang; Qing-Qing, Liu; Chang-Qing, Jin

    2016-07-01

    The layered semiconductor BaFZnAs with the tetragonal ZrCuSiAs-type structure has been successfully synthesized. Both the in-situ high-pressure synchrotron x-ray diffraction and the high-pressure Raman scattering measurements demonstrate that the structure of BaFZnAs is stable under pressure up to 17.5 GPa at room temperature. The resistivity and the magnetic susceptibility data show that BaFZnAs is a non-magnetic semiconductor. BaFZnAs is recommended as a candidate of the host material of diluted magnetic semiconductor. Project supported by the National Natural Science Foundation of China and Project of Ministry of Science and Technology of China.

  19. Stress-induced structural plasticity of medial amygdala stellate neurons and rapid prevention by a candidate antidepressant

    Science.gov (United States)

    Lau, T.; Bigio, B.; Zelli, D.; McEwen, BS.; Nasca, C.

    2016-01-01

    The adult brain is capable of adapting to internal and external stressors by undergoing structural plasticity, and failure to be resilient and preserve normal structure and function is likely to contribute to depression and anxiety disorders. While the hippocampus has provided the gateway for understanding stress effects on the brain, less is known about the amygdala, a key brain area involved in the neural circuitry of fear and anxiety. Here, in mice more vulnerable to stressors, we demonstrate structural plasticity within the medial and basolateral regions of the amygdala in response to prolonged 21day chronic restraint stress (CRS). Three days before the end of CRS, treatment with the putative, rapidly acting antidepressant, acetyl-L-carnitine (LAC) in the drinking water opposed the direction of these changes. Behaviorally, the LAC treatment during the last part of CRS enhanced resilience, opposing the effects of CRS, as shown by an increased social interaction and reduced passive behavior in a forced swim test. Furthermore, CRS mice treated with LAC show resilience of the CRS-induced structural remodeling of medial amygdala (MeA) stellate neurons. Within the basolateral (BLA) amygdala, LAC did not reduce, but slightly enhanced, the CRS-increased length and number of intersections of pyramidal neurons. No structural changes were observed in MeA bipolar neurons, BLA stellate neurons, or in lateral amygdala (LA) stellate neurons. Our findings identify MeA stellate neurons as an important component in the responses to stress and LAC action and show that LAC can promote structural plasticity of the MeA. This may be useful as a model for increasing resilience to stressors in at risk populations. PMID:27240534

  20. Irreducible complexity of iterated symmetric bimodal maps

    Directory of Open Access Journals (Sweden)

    J. P. Lampreia

    2005-01-01

    Full Text Available We introduce a tree structure for the iterates of symmetric bimodal maps and identify a subset which we prove to be isomorphic to the family of unimodal maps. This subset is used as a second factor for a ∗-product that we define in the space of bimodal kneading sequences. Finally, we give some properties for this product and study the ∗-product induced on the associated Markov shifts.

  1. Carbon fiber composites application in ITER plasma facing components

    Science.gov (United States)

    Barabash, V.; Akiba, M.; Bonal, J. P.; Federici, G.; Matera, R.; Nakamura, K.; Pacher, H. D.; Rödig, M.; Vieider, G.; Wu, C. H.

    1998-10-01

    Carbon Fiber Composites (CFCs) are one of the candidate armour materials for the plasma facing components of the International Thermonuclear Experimental Reactor (ITER). For the present reference design, CFC has been selected as armour for the divertor target near the plasma strike point mainly because of unique resistance to high normal and off-normal heat loads. It does not melt under disruptions and might have higher erosion lifetime in comparison with other possible armour materials. Issues related to CFC application in ITER are described in this paper. They include erosion lifetime, tritium codeposition with eroded material and possible methods for the removal of the codeposited layers, neutron irradiation effect, development of joining technologies with heat sink materials, and thermomechanical performance. The status of the development of new advanced CFCs for ITER application is also described. Finally, the remaining R&D needs are critically discussed.

  2. Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors with Clinical Candidate Potential

    Energy Technology Data Exchange (ETDEWEB)

    Coteron, Jose M.; Marco, Maria; Esquivias, Jorge; Deng, Xiaoyi; White, Karen L.; White, John; Koltun, Maria; El Mazouni, Farah; Kokkonda, Sreekanth; Katneni, Kasiram; Bhamidipati, Ravi; Shackleford, David M.; Angulo-Barturen, Inigo; Ferrer, Santiago B.; Jimenez-Diaz, Maria Belen; Gamo, Francisco-Javier; Goldsmith, Elizabeth J.; Charman, William N.; Bathurst, Ian; Floyd, David; Matthews, David; Burrows, Jeremy N.; Rathod, Pradipsinh K.; Charman, Susan A.; Phillips, Margaret A. (UWASH); (MMV, Switzerland); (GSK); (Monash); (UW); (UTSMC)

    2012-02-27

    Drug therapy is the mainstay of antimalarial therapy, yet current drugs are threatened by the development of resistance. In an effort to identify new potential antimalarials, we have undertaken a lead optimization program around our previously identified triazolopyrimidine-based series of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitors. The X-ray structure of PfDHODH was used to inform the medicinal chemistry program allowing the identification of a potent and selective inhibitor (DSM265) that acts through DHODH inhibition to kill both sensitive and drug resistant strains of the parasite. This compound has similar potency to chloroquine in the humanized SCID mouse P. falciparum model, can be synthesized by a simple route, and rodent pharmacokinetic studies demonstrated it has excellent oral bioavailability, a long half-life and low clearance. These studies have identified the first candidate in the triazolopyrimidine series to meet previously established progression criteria for efficacy and ADME properties, justifying further development of this compound toward clinical candidate status.

  3. Some geometrical iteration methods for nonlinear equations

    Institute of Scientific and Technical Information of China (English)

    LU Xing-jiang; QIAN Chun

    2008-01-01

    This paper describes geometrical essentials of some iteration methods (e.g. Newton iteration,secant line method,etc.) for solving nonlinear equations and advances some geomet-rical methods of iteration that are flexible and efficient.

  4. PICARD ITERATION FOR NONSMOOTH EQUATIONS

    Institute of Scientific and Technical Information of China (English)

    Song-bai Sheng; Hui-fu Xu

    2001-01-01

    This paper presents an analysis of the generalized Newton method, approximate Newton methods, and splitting methods for solving nonsmooth equations from Picard iteration viewpoint. It is proved that the radius of the weak Jacobian (RGJ) of Picard iteration function is equal to its least Lipschitz constant. Linear convergence or superlinear convergence results can be obtained provided that RGJ of the Picard iteration function at a solution point is less than one or equal to zero. As for applications, it is pointed out that the approximate Newton methods, the generalized Newton method for piecewise C1problems and splitting methods can be explained uniformly with the same viewpoint.

  5. The first fusion reactor: ITER

    Science.gov (United States)

    Campbell, D. J.

    2016-11-01

    Established by the signature of the ITER Agreement in November 2006 and currently under construction at St Paul-lez-Durance in southern France, the ITER project [1,2] involves the European Union (including Switzerland), China, India, Japan, the Russian Federation, South Korea and the United States. ITER (`the way' in Latin) is a critical step in the development of fusion energy. Its role is to provide an integrated demonstration of the physics and technology required for a fusion power plant based on magnetic confinement.

  6. Iterative optimization in inverse problems

    CERN Document Server

    Byrne, Charles L

    2014-01-01

    Iterative Optimization in Inverse Problems brings together a number of important iterative algorithms for medical imaging, optimization, and statistical estimation. It incorporates recent work that has not appeared in other books and draws on the author's considerable research in the field, including his recently developed class of SUMMA algorithms. Related to sequential unconstrained minimization methods, the SUMMA class includes a wide range of iterative algorithms well known to researchers in various areas, such as statistics and image processing. Organizing the topics from general to more

  7. A new back-and-forth iterative method for time-reversed convection modeling: Implications for the Cenozoic evolution of 3-D structure and dynamics of the mantle

    Science.gov (United States)

    Glišović, Petar; Forte, Alessandro M.

    2016-06-01

    The 3-D distribution of buoyancy in the convecting mantle drives a suite of convection-related manifestations. Although seismic tomography is providing increasingly resolved images of the present-day mantle heterogeneity, the distribution of mantle density variations in the geological past is unknown, and, by implication, this is true for the convection-related observables. The one major exception is tectonic plate motions, since geologic data are available to estimate their history and they currently provide the only available constraints on the evolution of 3-D mantle buoyancy in the past. We developed a new back-and-forth iterative method for time-reversed convection modeling with a procedure for matching plate velocity data at different instants in the past. The crucial aspect of this reconstruction methodology is to ensure that at all times plates are driven by buoyancy forces in the mantle and not vice versa. Employing tomography-based retrodictions over the Cenozoic, we estimate the global amplitude of the following observables: dynamic surface topography, the core-mantle boundary ellipticity, the free-air gravity anomalies, and the global divergence rates of tectonic plates. One of the major benefits of the new data assimilation method is the stable recovery of much shorter wavelength changes in heterogeneity than was possible in our previous work. We now resolve what appears to be two-stage subduction of the Farallon plate under the western U.S. and a deeply rooted East African Plume that is active under the Ethiopian volcanic fields during the Early Eocene.

  8. SUMMARY REPORT-FY2006 ITER WORK ACCOMPLISHED

    Energy Technology Data Exchange (ETDEWEB)

    Martovetsky, N N

    2006-04-11

    Six parties (EU, Japan, Russia, US, Korea, China) will build ITER. The US proposed to deliver at least 4 out of 7 modules of the Central Solenoid. Phillip Michael (MIT) and I were tasked by DoE to assist ITER in development of the ITER CS and other magnet systems. We work to help Magnets and Structure division headed by Neil Mitchell. During this visit I worked on the selected items of the CS design and carried out other small tasks, like PF temperature margin assessment.

  9. Efficient use of iterative solvers in nested topology optimization

    DEFF Research Database (Denmark)

    Amir, Oded; Stolpe, Mathias; Sigmund, Ole

    2010-01-01

    In the nested approach to structural optimization, most of the computational effort is invested in the solution of the analysis equations. In this study, it is suggested to reduce this computational cost by using an approximation to the solution of the analysis problem, generated by a Krylov...... subspace iterative solver. By choosing convergence criteria for the iterative solver that are strongly related to the optimization objective and to the design sensitivities, it is possible to terminate the iterative solution of the nested equations earlier compared to traditional convergence measures...

  10. Establishment of design and fabrication technology and domestic qualification for ITER blanket system

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Bong Guen; In, S. R.; Bae, Y. D. (and others)

    2006-02-15

    To obtain and analyze the detailed design and manufacturing technology of the blanket system for each components, the related data are collected through the various sources. And also, design processes and results of the FWs, shield blocks, and TBMs are investigated. From these analysis of the blanket R and D status of each party, we develop the KO R and D plan and it is used in the selection of manufacturing method and the materials. For the ITA16-10 subtask1, we had the official agreement with ITER IT in December 2004 for the qualification of the FW panel fabrication methods and to establish the NDT methods for the FW panel. From the technical reports we published, we compare the manufacturing methods and the proposed material for each component according to the parties. Be is proposed as a plasma facing material and most parties have interest in S-65C. Cu alloy is proposed as a heat sink material and DSCu or CuCrZr are investigated now. For the structural material, stainless steel such as SS316L(N) is investigated internationally. HIP and brazing are proposed as the manufacturing methods. In order to establish the blanket system technology, design contents of shield block by ITER IT and other parties were investigated through participating the international workshop and meeting, dispatching the researcher to the ITER IT or other parties to collect the drafting and 3D modeling files. The modification items of blanket design were investigated and a researcher was dispatched in the ITER IT and participated in the analysis on cooling problem in shield block such as front header and drilled manifold. To investigate the development status of TBM, we participated the 14th TBWG meeting and proposed the KO HCSB and HCML as candidates. And also, we obtain the R and D results of other parties and make document about the R and D status of other parties for the TBM. Finally, we establish the KO TBM R and D plan and proposed it to ITER IT and other parties. In which, the

  11. CH3NH3PbI3, A Potential Solar Cell Candidate: Structural and Spectroscopic Investigations.

    Science.gov (United States)

    Nandi, Pronoy; Giri, Chandan; Joseph, Boby; Rath, S; Manju, U; Topwal, D

    2016-12-15

    Hybrid organic-inorganic metal halides of the type CH3NH3PbX3 have emerged as potential materials for photovoltaic applications. In this paper we discuss structural, electronic, and optical spectroscopy investigations performed on high quality single crystals of CH3NH3PbI3. Our results conclusively suggest that CH3NH3PbI3 crystallizes in centrosymmetric space group and the methylammonium moiety exhibits disordered packing at room temperature. Extracted values of the exciton binding energy, the electron-phonon coupling constant, and the schematic energy level diagram constructed from the emission broadening, Raman, and photoemission spectroscopy measurements clearly show the potential of this system in photovoltaic applications.

  12. The Use of Chemical-Chemical Interaction and Chemical Structure to Identify New Candidate Chemicals Related to Lung Cancer.

    Directory of Open Access Journals (Sweden)

    Lei Chen

    Full Text Available Lung cancer causes over one million deaths every year worldwide. However, prevention and treatment methods for this serious disease are limited. The identification of new chemicals related to lung cancer may aid in disease prevention and the design of more effective treatments. This study employed a weighted network, constructed using chemical-chemical interaction information, to identify new chemicals related to two types of lung cancer: non-small lung cancer and small-cell lung cancer. Then, a randomization test as well as chemical-chemical interaction and chemical structure information were utilized to make further selections. A final analysis of these new chemicals in the context of the current literature indicates that several chemicals are strongly linked to lung cancer.

  13. Iterants, Fermions and Majorana Operators

    Science.gov (United States)

    Kauffman, Louis H.

    Beginning with an elementary, oscillatory discrete dynamical system associated with the square root of minus one, we study both the foundations of mathematics and physics. Position and momentum do not commute in our discrete physics. Their commutator is related to the diffusion constant for a Brownian process and to the Heisenberg commutator in quantum mechanics. We take John Wheeler's idea of It from Bit as an essential clue and we rework the structure of that bit to a logical particle that is its own anti-particle, a logical Marjorana particle. This is our key example of the amphibian nature of mathematics and the external world. We show how the dynamical system for the square root of minus one is essentially the dynamics of a distinction whose self-reference leads to both the fusion algebra and the operator algebra for the Majorana Fermion. In the course of this, we develop an iterant algebra that supports all of matrix algebra and we end the essay with a discussion of the Dirac equation based on these principles.

  14. Rollout sampling approximate policy iteration

    NARCIS (Netherlands)

    Dimitrakakis, C.; Lagoudakis, M.G.

    2008-01-01

    Several researchers have recently investigated the connection between reinforcement learning and classification. We are motivated by proposals of approximate policy iteration schemes without value functions, which focus on policy representation using classifiers and address policy learning as a

  15. Iterative solution of linear systems

    Science.gov (United States)

    Freund, Roland W.; Golub, Gene H.; Nachtigal, Noel M.

    1992-01-01

    Recent advances in the field of iterative methods for solving large linear systems are reviewed. The main focus is on developments in the area of conjugate gradient-type algorithms and Krylov subspace methods for nonHermitian matrices.

  16. Updated safety analysis of ITER

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, Neill, E-mail: neill.taylor@iter.org [ITER Organization, CS 90 046, 13067 St Paul Lez Durance Cedex (France); Baker, Dennis; Ciattaglia, Sergio; Cortes, Pierre; Elbez-Uzan, Joelle; Iseli, Markus; Reyes, Susana; Rodriguez-Rodrigo, Lina; Rosanvallon, Sandrine; Topilski, Leonid [ITER Organization, CS 90 046, 13067 St Paul Lez Durance Cedex (France)

    2011-10-15

    An updated version of the ITER Preliminary Safety Report has been produced and submitted to the licensing authorities. It is revised and expanded in response to requests from the authorities after their review of an earlier version in 2008, to reflect enhancements in ITER safety provisions through design changes, to incorporate new and improved safety analyses and to take into account other ITER design evolution. The updated analyses show that changes to the Tokamak cooling water system design have enhanced confinement and reduced potential radiological releases as well as removing decay heat with very high reliability. New and updated accident scenario analyses, together with fire and explosion risk analyses, have shown that design provisions are sufficient to minimize the likelihood of accidents and reduce potential consequences to a very low level. Taken together, the improvements provided a stronger demonstration of the very good safety performance of the ITER design.

  17. Cooperation between CERN and ITER

    CERN Multimedia

    2008-01-01

    CERN and the International Fusion Organisation ITER have just signed a first cooperation agreeement. Kaname Ikeda, the Director-General of the International Fusion Energy Organisation (ITER) (on the right) and Robert Aymar, Director-General of CERN, signing the agreement.The Director-General of the International Fusion Energy Organization, Mr Kaname Ikeda, and CERN Director-General, Robert Aymar, signed a cooperation agreement at a meeting on the Meyrin site on Thursday 6 March. One of the main purposes of this agreement is for CERN to give ITER the benefit of its experience in the field of technology as well as in administrative domains such as finance, procurement, human resources and informatics through the provision of consultancy services. Currently in its start-up phase at its Cadarache site, 70 km from Marseilles (France), ITER will focus its research on the scientific and technical feasibility of using fusion energy as a fu...

  18. The Cryostat and Subsystems Development at ITER

    Science.gov (United States)

    Sekachev, Igor; Meekins, Michael; Sborchia, Carlo; Vitupier, Guillaume; Xie, Han; Zhou, Caipin

    ITER is a large experimental tokamak being built to research fusion power. The ITER cryostat is a multifunctional system which provides vacuum insulation for the superconducting magnets operating at 4.5 K and for the thermal shield operating at 80 K. It also serves as a structural support for the tokamak and provides access ways and corridors to the vacuum vessel for diagnostic lines of sight, additional heating beams and the deployment of remote handling equipment. The cryostat has feed-through penetrations for all the equipment connecting elements of systems outside the cryostat to the corresponding elements inside the cryostat. The cryostat is a vacuum containment vessel having a very large volume of ∼16000 m3 designed to be evacuated to a base pressure of 10-4 Pa. Design details of the cryostat and associated systems, including Torus Cryopump Housing (TCPH), are discussed. Status report of the cryostat developments is presented.

  19. UV and X-ray structural studies of a 101-residue long Tat protein from a HIV-1 primary isolate and of its mutated, detoxified, vaccine candidate.

    Science.gov (United States)

    Foucault, Marine; Mayol, Katia; Receveur-Bréchot, Véronique; Bussat, Marie-Claire; Klinguer-Hamour, Christine; Verrier, Bernard; Beck, Alain; Haser, Richard; Gouet, Patrice; Guillon, Christophe

    2010-05-01

    The 101-residue long Tat protein of primary isolate 133 of the human immunodeficiency virus type 1 (HIV-1), wt-Tat(133) displays a high transactivation activity in vitro, whereas the mutant thereof, STLA-Tat(133), a vaccine candidate for HIV-1, has none. These two proteins were chemically synthesized and their biological activity was validated. Their structural properties were characterized using circular dichroism (CD), fluorescence emission, gel filtration, dynamic light scattering, and small angle X-ray scattering (SAXS) techniques. SAXS studies revealed that both proteins were extended and belong to the family of intrinsically unstructured proteins. CD measurements showed that wt-Tat(133) or STLA-Tat(133) underwent limited structural rearrangements when complexed with specific fragments of antibodies. Crystallization trials have been performed on the two forms, assuming that the Tat(133) proteins might have a better propensity to fold in supersaturated conditions, and small crystals have been obtained. These results suggest that biologically active Tat protein is natively unfolded and requires only a limited gain of structure for its function.

  20. ITER leader to head CERN

    CERN Multimedia

    Feder, Toni

    2003-01-01

    After successfully chairing an external review committee for CERN last year, Robert Aymar will leave ITER to become director general of the European particle physics laboratory rom 2004. Before ITER he also successfully managed the startup or Tore Supra. He will attempt to ensure that the LHC begins operating in 2007 - two years late - and is paid for by 2010 and will also start the planning for life after the LHC (1 page)

  1. ITER diagnostic system: Vacuum interface

    Energy Technology Data Exchange (ETDEWEB)

    Patel, K.M., E-mail: Kaushal.Patel@iter.org [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-Lez-Durance (France); Udintsev, V.S.; Hughes, S.; Walker, C.I.; Andrew, P.; Barnsley, R.; Bertalot, L. [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-Lez-Durance (France); Drevon, J.M. [Bertin Technologies, BP 22, 13762 Aix-en Provence cedex 3 (France); Encheva, A. [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-Lez-Durance (France); Kashchuk, Y. [Institution “PROJECT CENTER ITER”, 1, Akademika Kurchatova pl., Moscow (Russian Federation); Maquet, Ph. [Bertin Technologies, BP 22, 13762 Aix-en Provence cedex 3 (France); Pearce, R.; Taylor, N.; Vayakis, G.; Walsh, M.J. [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-Lez-Durance (France)

    2013-10-15

    Diagnostics play an essential role for the successful operation of the ITER tokamak. They provide the means to observe control and to measure plasma during the operation of ITER tokamak. The components of the diagnostic system in the ITER tokamak will be installed in the vacuum vessel, in the cryostat, in the upper, equatorial and divertor ports, in the divertor cassettes and racks, as well as in various buildings. Diagnostic components that are placed in a high radiation environment are expected to operate for the life of ITER. There are approx. 45 diagnostic systems located on ITER. Some diagnostics incorporate direct or independently pumped extensions to maintain their necessary vacuum conditions. They require a base pressure less than 10{sup −7} Pa, irrespective of plasma operation, and a leak rate of less than 10{sup −10} Pa m{sup 3} s{sup −1}. In all the cases it is essential to maintain the ITER closed fuel cycle. These directly coupled diagnostic systems are an integral part of the ITER vacuum containment and are therefore subject to the same design requirements for tritium and active gas confinement, for all normal and accidental conditions. All the diagnostics, whether or not pumped, incorporate penetration of the vacuum boundary (i.e. window assembly, vacuum feedthrough etc.) and demountable joints. Monitored guard volumes are provided for all elements of the vacuum boundary that are judged to be vulnerable by virtue of their construction, material, load specification etc. Standard arrangements are made for their construction and for the monitoring, evacuating and leak testing of these volumes. Diagnostic systems are incorporated at more than 20 ports on ITER. This paper will describe typical and particular arrangements of pumped diagnostic and monitored guard volume. The status of the diagnostic vacuum systems, which are at the start of their detailed design, will be outlined and the specific features of the vacuum systems in ports and extensions

  2. Electronic structure of simple phosphorus containing molecules [C,xH,O,P] candidate for astrobiology (x=1, 3, 5).

    Science.gov (United States)

    Lattelais, M; Pauzat, F; Pilmé, J; Ellinger, Y

    2008-04-21

    The present report is a prospective study aimed at finding phosphorus containing compounds for astrobiology. Since PN, PC and HCP are the only species detected so far, it was deemed reasonable to enlarge the quest for phosphorus compounds to mixed carbon oxygen containing compounds [C,xH,O,P] analogue to the CHON family. Ab initio Møller-Plesset (MP2), Coupled Cluster (CCSD(T)) and Density Functional Theory (DFT) were used. State of the art level of theory, CCSD(T)/cc-pVQZ, was necessary to show that CH3-PH2=O is the most stable isomer, with CH3-PH-OH close by in the [C,5H,O,P] sub-family. This structure has the same C-P-O connectivity as the most stable compound of the [C,3H,O,P] sub-family, CH3-P=O but differs from the simplest [C,H,O,P] system HP=C=O. Rotational constants B=7.1377 and C=6.0636 GHz associated with a dipole moment of 4.2 Debye together with an IR spectrum with very strong bands at 1214, 2282, 2264 and 1039 cm(-1) have been calculated for CH3-PH2=O. For CH3-P=O, one has B=7.9881 and C=6.4659 GHz, a dipole moment of 2.9 Debye and four IR bands at 1198, 623, 835, 1256 cm(-1) of medium intensity. The simplest HPCO system with B=5.5206 and 5.3952 GHz and a dipole moment of 0.8 Debye has only one very strong IR frequency at 2037 cm(-1). The above values should be precise enough to encourage laboratory experiments on these prototype molecules.

  3. ITER Central Solenoid Module Fabrication

    Energy Technology Data Exchange (ETDEWEB)

    Smith, John [General Atomics, San Diego, CA (United States)

    2016-09-23

    The fabrication of the modules for the ITER Central Solenoid (CS) has started in a dedicated production facility located in Poway, California, USA. The necessary tools have been designed, built, installed, and tested in the facility to enable the start of production. The current schedule has first module fabrication completed in 2017, followed by testing and subsequent shipment to ITER. The Central Solenoid is a key component of the ITER tokamak providing the inductive voltage to initiate and sustain the plasma current and to position and shape the plasma. The design of the CS has been a collaborative effort between the US ITER Project Office (US ITER), the international ITER Organization (IO) and General Atomics (GA). GA’s responsibility includes: completing the fabrication design, developing and qualifying the fabrication processes and tools, and then completing the fabrication of the seven 110 tonne CS modules. The modules will be shipped separately to the ITER site, and then stacked and aligned in the Assembly Hall prior to insertion in the core of the ITER tokamak. A dedicated facility in Poway, California, USA has been established by GA to complete the fabrication of the seven modules. Infrastructure improvements included thick reinforced concrete floors, a diesel generator for backup power, along with, cranes for moving the tooling within the facility. The fabrication process for a single module requires approximately 22 months followed by five months of testing, which includes preliminary electrical testing followed by high current (48.5 kA) tests at 4.7K. The production of the seven modules is completed in a parallel fashion through ten process stations. The process stations have been designed and built with most stations having completed testing and qualification for carrying out the required fabrication processes. The final qualification step for each process station is achieved by the successful production of a prototype coil. Fabrication of the first

  4. RECOVERY OF THE CANDIDATE PROTOPLANET HD 100546 b WITH GEMINI/NICI AND DETECTION OF ADDITIONAL (PLANET-INDUCED?) DISK STRUCTURE AT SMALL SEPARATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Currie, Thayne; Kudo, Tomoyuki [NAOJ, Subaru Telescope, 650 N' Aohoku Pl., Hilo, HI 96720 (United States); Muto, Takayuki [Division of Liberal Arts, Kogashin University, 1-24-2, Nishi-Shinjuku, Shinijuku-ku, Tokyo 163-8677 (Japan); Honda, Mitsuhiko [Department of Mathematics and Physics, Kanagawa University, 2946 Tsuchiya, Hiratsuka 259-1293 (Japan); Brandt, Timothy D. [Astrophysics Department, Institute for Advanced Study, Princeton, NJ 08540 (United States); Grady, Carol [Eureka Scientific, 2452 Delmer, Suite 100, Oakland, CA96002 (United States); Fukagawa, Misato [Graduate School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka 560-0043 (Japan); Burrows, Adam [Department of Astrophysical Sciences, Princeton University, 7 Ivy Lane, Princeton, NJ 08544-1001 (United States); Janson, Markus [Stockholm University, SE-106 91 Stockholm (Sweden); Kuzuhara, Masayuki [Department of Earth and Planetary Sciences, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8551 (Japan); McElwain, Michael W. [Exoplanets and Stellar Astrophysics Laboratory, Code 667, Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Follette, Katherine [Department of Astronomy, Steward Observatory, University of Arizona, 933 North Cherry Avenue, Tucson, AZ 85721-0065 (United States); Hashimoto, Jun [H. L. Dodge Department of Physics and Astronomy, University of Oklahoma, 440 W. Brooks St Norman, OK 73019 (United States); Henning, Thomas [Max Planck Institute for Astronomy, Königstuhl 17, D-69117 Heidelberg (Germany); Kandori, Ryo; Kusakabe, Nobuhiko; Morino, Jun-ichi; Nishikawa, Jun [National Astronomical Observatory of Japan, 2-21-1, Osawa, Mitaka, Tokyo 181-8588 (Japan); Kwon, Jungmi; Mede, Kyle, E-mail: currie@naoj.org [Department of Astronomy, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); and others

    2014-12-01

    We report the first independent, second epoch (re-)detection of a directly imaged protoplanet candidate. Using L' high-contrast imaging of HD 100546 taken with the Near-Infrared Coronagraph and Imager on Gemini South, we recover ''HD 100546 b'' with a position and brightness consistent with the original Very Large Telescope/NAos-COnica detection from Quanz et al., although data obtained after 2013 will be required to decisively demonstrate common proper motion. HD 100546 b may be spatially resolved, up to ≈12-13 AU in diameter, and is embedded in a finger of thermal IR-bright, polarized emission extending inward to at least 0.''3. Standard hot-start models imply a mass of ≈15 M{sub J} . However, if HD 100546 b is newly formed or made visible by a circumplanetary disk, both of which are plausible, its mass is significantly lower (e.g., 1-7 M{sub J} ). Additionally, we discover a thermal IR-bright disk feature, possibly a spiral density wave, at roughly the same angular separation as HD 100546 b but 90° away. Our interpretation of this feature as a spiral arm is not decisive, but modeling analyses using spiral density wave theory implies a wave launching point exterior to ≈0.''45 embedded within the visible disk structure: plausibly evidence for a second, hitherto unseen, wide-separation planet. With one confirmed protoplanet candidate and evidence for one to two others, HD 100546 is an important evolutionary precursor to intermediate-mass stars with multiple super-Jovian planets at moderate/wide separations like HR 8799.

  5. Iterative build OMIT maps: Map improvement by iterative model-building and refinement without model bias

    Energy Technology Data Exchange (ETDEWEB)

    Los Alamos National Laboratory, Mailstop M888, Los Alamos, NM 87545, USA; Lawrence Berkeley National Laboratory, One Cyclotron Road, Building 64R0121, Berkeley, CA 94720, USA; Department of Haematology, University of Cambridge, Cambridge CB2 0XY, England; Terwilliger, Thomas; Terwilliger, T.C.; Grosse-Kunstleve, Ralf Wilhelm; Afonine, P.V.; Moriarty, N.W.; Zwart, P.H.; Hung, L.-W.; Read, R.J.; Adams, P.D.

    2008-02-12

    A procedure for carrying out iterative model-building, density modification and refinement is presented in which the density in an OMIT region is essentially unbiased by an atomic model. Density from a set of overlapping OMIT regions can be combined to create a composite 'Iterative-Build' OMIT map that is everywhere unbiased by an atomic model but also everywhere benefiting from the model-based information present elsewhere in the unit cell. The procedure may have applications in the validation of specific features in atomic models as well as in overall model validation. The procedure is demonstrated with a molecular replacement structure and with an experimentally-phased structure, and a variation on the method is demonstrated by removing model bias from a structure from the Protein Data Bank.

  6. Structural determination of individual chemical species in a mixed system by iterative transformation factor analysis-based X-ray absorption spectroscopy combined with UV-visible absorption and quantum chemical calculation.

    Science.gov (United States)

    Ikeda, Atsushi; Hennig, Christoph; Rossberg, André; Tsushima, Satoru; Scheinost, Andreas C; Bernhard, Gert

    2008-02-15

    A multitechnique approach using extended X-ray absorption fine structure (EXAFS) spectroscopy based on iterative transformation factor analysis (ITFA), UV-visible absorption spectroscopy, and density functional theory (DFT) calculations has been performed in order to investigate the speciation of uranium(VI) nitrate species in acetonitrile and to identify the complex structure of individual species in the system. UV-visible spectral titration suggests that there are four different species in the system, that is, pure solvated species, mono-, di-, and trinitrate species. The pure EXAFS spectra of these individual species are extracted by ITFA from the measured spectral mixtures on the basis of the speciation distribution profile calculated from the UV-visible data. Data analysis of the extracted EXAFS spectra, with the help of DFT calculations, reveals the most probable complex structures of the individual species. The pure solvated species corresponds to a uranyl hydrate complex with an equatorial coordination number (CNeq) of 5, [UO2(H2O)5]2+. Nitrate ions tend to coordinate to the uranyl(VI) ion in a bidentate fashion rather than a unidentate one in acetonitrile for all the nitrate species. The mononitrate species forms the complex of [UO2(H2O)3NO3]+ with a CNeq value of 5, while the di- and trinitrate species have a CNeq value of 6, corresponding to [UO2(H2O)2(NO3)2]0 (D2h) and [UO2(NO3)3]- (D3h), respectively.

  7. A recursion identity for formal iterated logarithms and iterated exponentials

    CERN Document Server

    Robinson, Thomas J

    2010-01-01

    We prove a recursive identity involving formal iterated logarithms and formal iterated exponentials. These iterated logarithms and exponentials appear in a natural extension of the logarithmic formal calculus used in the study of logarithmic intertwining operators and logarithmic tensor category theory for modules for a vertex operator algebra. This extension has a variety of interesting arithmetic properties. We develop one such result here, the aforementioned recursive identity. We have applied this identity elsewhere to certain formal series expansions related to a general formal Taylor theorem and these series expansions in turn yield a sequence of combinatorial identities which have as special cases certain classical combinatorial identities involving (separately) the Stirling numbers of the first and second kinds.

  8. Technical issues of reduced activation ferritic/martensitic steels for fabrication of ITER test blanket modules

    Energy Technology Data Exchange (ETDEWEB)

    Tanigawa, H. [Japan Atomic Energy Agency, Tokai, Ibaraki 319-1195 (Japan)], E-mail: tanigawa.hiroyasu@jaea.go.jp; Hirose, T.; Shiba, K. [Japan Atomic Energy Agency, Tokai, Ibaraki 319-1195 (Japan); Kasada, R. [Institute of Advanced Energy, Kyoto University, Uji, Kyoto 611-0011 (Japan); Wakai, E. [Japan Atomic Energy Agency, Tokai, Ibaraki 319-1195 (Japan); Serizawa, H.; Kawahito, Y. [Joining and Welding Research Institute, Osaka University, Ibaraki, Osaka 567-0047 (Japan); Jitsukawa, S. [Japan Atomic Energy Agency, Tokai, Ibaraki 319-1195 (Japan); Kimura, A. [Institute of Advanced Energy, Kyoto University, Uji, Kyoto 611-0011 (Japan); Kohno, Y. [Department of Materials Science and Engineering, Muroran Institute of Technology, Muroran, Hokkaido 050-8585 (Japan); Kohyama, A. [Institute of Advanced Energy, Kyoto University, Uji, Kyoto 611-0011 (Japan); Katayama, S. [Joining and Welding Research Institute, Osaka University, Ibaraki, Osaka 567-0047 (Japan); Mori, H.; Nishimoto, K. [Division of Materials and Manufacturing Science, Osaka University, Ibaraki, Osaka 565-0871 (Japan); Klueh, R.L.; Sokolov, M.A.; Stoller, R.E.; Zinkle, S.J. [Materials Science and Technology Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831-6132 (United States)

    2008-12-15

    Reduced activation ferritic/martensitic steels (RAFMs) are recognized as the primary candidate structural materials for fusion blanket systems. The RAFM F82H was developed in Japan with emphasis on high-temperature properties and weldability. Extensive irradiation studies have conducted on F82H, and it has the most extensive available database of irradiated and unirradiated properties of all RAFMs. The objective of this paper is to review the R and D status of F82H and to identify the key technical issues for the fabrication of an ITER test blanket module (TBM) suggested from the recent research achievements in Japan. This work clarified that the primary issues with F82H involve welding techniques and the mechanical properties of weld joints. This is the result of the distinctive nature of the joint caused by the phase transformation that occurs in the weld joint during cooling, and its impact on the design of a TBM will be discussed.

  9. Relaxation Criteria for Iterated Traffic Simulations

    Science.gov (United States)

    Kelly, Terence; Nagel, Kai

    Iterative transportation microsimulations adjust traveler route plans by iterating between a microsimulation and a route planner. At each iteration, the route planner adjusts individuals' route choices based on the preceding microsimulations. Empirically, this process yields good results, but it is usually unclear when to stop the iterative process when modeling real-world traffic. This paper investigates several criteria to judge relaxation of the iterative process, emphasizing criteria related to traveler decision-making.

  10. Voila: A visual object-oriented iterative linear algebra problem solving environment

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, H.C.; Hayes, L.J. [Univ. of Texas, Austin, TX (United States)

    1994-12-31

    Application of iterative methods to solve a large linear system of equations currently involves writing a program which calls iterative method subprograms from a large software package. These subprograms have complex interfaces which are difficult to use and even more difficult to program. A problem solving environment specifically tailored to the development and application of iterative methods is needed. This need will be fulfilled by Voila, a problem solving environment which provides a visual programming interface to object-oriented iterative linear algebra kernels. Voila will provide several quantum improvements over current iterative method problem solving environments. First, programming and applying iterative methods is considerably simplified through Voila`s visual programming interface. Second, iterative method algorithm implementations are independent of any particular sparse matrix data structure through Voila`s object-oriented kernels. Third, the compile-link-debug process is eliminated as Voila operates as an interpreter.

  11. A Linear Iterative Unfolding Method

    CERN Document Server

    Laszlo, Andras

    2011-01-01

    A frequently faced task in experimental physics is to measure the probability distribution of some quantity. Often this quantity to be measured is smeared by a non-ideal detector response or by some physical process. The procedure of removing this smearing effect from the measured distribution is called unfolding, and is a delicate problem in signal processing. Due to the numerical ill-posedness of this task, various methods were invented which, given some assumptions on the initial probability distribution, try to regularize the problem. Most of these methods definitely introduce bias on the estimate of the initial probability distribution. We propose a linear iterative method (motivated by the Neumann series / Landweber iteration known in functional analysis), which has the advantage that no assumptions on the initial probability distribution is needed, and the only regularization parameter is the stopping order of the iteration. Convergence is proved under certain quite general conditions, which hold for p...

  12. Construction Safety Forecast for ITER

    Energy Technology Data Exchange (ETDEWEB)

    cadwallader, lee charles

    2006-11-01

    The International Thermonuclear Experimental Reactor (ITER) project is poised to begin its construction activity. This paper gives an estimate of construction safety as if the experiment was being built in the United States. This estimate of construction injuries and potential fatalities serves as a useful forecast of what can be expected for construction of such a major facility in any country. These data should be considered by the ITER International Team as it plans for safety during the construction phase. Based on average U.S. construction rates, ITER may expect a lost workday case rate of < 4.0 and a fatality count of 0.5 to 0.9 persons per year.

  13. Rollout Sampling Approximate Policy Iteration

    CERN Document Server

    Dimitrakakis, Christos

    2008-01-01

    Several researchers have recently investigated the connection between reinforcement learning and classification. We are motivated by proposals of approximate policy iteration schemes without value functions which focus on policy representation using classifiers and address policy learning as a supervised learning problem. This paper proposes variants of an improved policy iteration scheme which addresses the core sampling problem in evaluating a policy through simulation as a multi-armed bandit machine. The resulting algorithm offers comparable performance to the previous algorithm achieved, however, with significantly less computational effort. An order of magnitude improvement is demonstrated experimentally in two standard reinforcement learning domains: inverted pendulum and mountain-car.

  14. AN ADAPTIVE ITERATION METHOD FOR STRUCTURAL STATIC REANALYSIS OF TOPOLOGICAL MODIFICATIONS%结构拓扑修改静态重分析自适应迭代方法

    Institute of Scientific and Technical Information of China (English)

    杨志军; 陈新; 吴晓明; 陈塑寰

    2009-01-01

    Based on the Guyan reduction and epsilon algorithm, an adaptive iteration method for structural static reanalysis of topological modification is presented. In this process, the equations of the newly added degree of freedoms (DOFS) (if any) are condensed to the original structure by means of Guyan reduction. And then, the basis vector is formed using Neumann serial according to the increment of the stiffness matrix, and the epsilon algorithm is used to accelerate the convergence of the partial sum of the basis vectors. An error evaluation method is introduced to control the accuracy of the iteration adaptively. A numerical example is given to compare the computational cost and approximation accuracy between the combined approximation and the presented method, the numerical results show that the present method is effective and easy to integrate into a general optimization approach.%基于Guyan缩减和Epsilon算法,提出了结构拓扑修改静态重分析的自适应迭代方法.首先将新增加的自由度通过Guyan缩减方法凝聚到原结构自由度上,形成缩减方程.其次,根据刚度矩阵增量,利用Neumann级数建立基向量,采用向量Epsilon算法对基向量部分和系列进行迭代加速,并给出了控制迭代收敛精度的误差计算方法,可以根据结构改变的大小自适应选择迭代次数,从而快速求出原结构自由度的位移.新增加自由度的位移可从缩减方程恢复得到.给出了一个数值算例,将该方法与组合近似法(CA)进行比较.数值计算结果表明,该方法可以根据精度要求自动选择迭代次数,且计算效率比CA方法高.

  15. Systematic structure modifications of multitarget prostate cancer drug candidate galeterone to produce novel androgen receptor down-regulating agents as an approach to treatment of advanced prostate cancer.

    Science.gov (United States)

    Purushottamachar, Puranik; Godbole, Abhijit M; Gediya, Lalji K; Martin, Marlena S; Vasaitis, Tadas S; Kwegyir-Afful, Andrew K; Ramalingam, Senthilmurugan; Ates-Alagoz, Zeynep; Njar, Vincent C O

    2013-06-27

    As part of our program to explore the influence of small structural modifications of our drug candidate 3β-(hydroxy)-17-(1H-benzimidazol-1-yl)androsta-5,16-diene (galeterone, 5) on the modulation of the androgen receptor (AR), we have prepared and evaluated a series of novel C-3, C-16, and C-17 analogues. Using structure activity analysis, we established that the benzimidazole moiety at C-17 is essential and optimal and also that hydrophilic and heteroaromatic groups at C-3 enhance both antiproliferative (AP) and AR degrading (ARD) activities. The most potent antiproliferative compounds were 3β-(1H-imidazole-1-carboxylate)-17-(1H-benzimidazol-1-yl)androsta-5,16-diene (47), 3-((EZ)-hydroximino)-17-(1H-benzimidazol-1-yl)androsta-4,16-diene (36), and 3β-(pyridine-4-carboxylate)-17-(1H-benzimidazol-1-yl)androsta-5,16-diene (43), with GI50 values of 0.87, 1.91, and 2.57 μM, respectively. Compared to 5, compound 47 was 4- and 8-fold more potent with respect to AP and ARD activities, respectively. Importantly, we also discovered that our compounds, including 5, 36, 43, and 47, could degrade both full-length and truncated ARs in CWR22rv1 human prostate cancer cells. With these activities, they have potential for development as new drugs for the treatment of all forms of prostate cancer.

  16. Identification of candidates for interacting partners of the tail domain of DcNMCP1, a major component of the Daucus carota nuclear lamina-like structure.

    Science.gov (United States)

    Mochizuki, Ryota; Tsugama, Daisuke; Yamazaki, Michihiro; Fujino, Kaien; Masuda, Kiyoshi

    2017-02-01

    NMCP/CRWN (NUCLEAR MATRIX CONSTITUENT PROTEIN/CROWDED NUCLEI) is a major component of a protein fibrous meshwork (lamina-like structure) on the plant inner nuclear membrane. NMCP/CRWN contributes to regulating nuclear shape and nuclear functions. An NMCP/CRWN protein in Daucus carota (DcNMCP1) is localized to the nuclear periphery in interphase cells, and surrounds chromosomes in cells in metaphase and anaphase. The N-terminal region and the C-terminal region of DcNMCP1 are both necessary for localizing DcNMCP1 to the nuclear periphery. Here candidate interacting partners of the amino acid position 975-1053 of DcNMCP1 (T975-1053), which is present in the C-terminal region and contains a conserved sequence that plays a role in localizing DcNMCP1 to the nuclear periphery, are screened for. Arabidopsis thaliana nuclear proteins were subjected to far-Western blotting with GST-fused T975-1053 as a probe, and signals were detected at the positions corresponding to ∼70, ∼40, and ∼18 kDa. These ∼70, ∼40, and ∼18 kDa nuclear proteins were identified by mass spectrometry, and subjected to a yeast 2-hybrid (Y2H) analysis with T975-1053 as bait. In this analysis, the ∼40 kDa protein ARP7, which is a nuclear actin-related protein possibly involved in regulating chromatin structures, was confirmed to interact with T975-1053. Independently of the far-Western blotting, a Y2H screen was performed using T975-1053 as bait. Targeted Y2H assays confirmed that 3 proteins identified in the screen, MYB3, SINAT1, and BIM1, interact with T975-1053. These proteins might have roles in NMCP/CRWN protein-mediated biologic processes.

  17. Design of ITER vacuum vessel in-wall shielding

    Energy Technology Data Exchange (ETDEWEB)

    Wang, X., E-mail: xiaoyu.wang@iter.org [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France); Ioki, K. [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France); Morimoto, M. [Mitsubishi Heavy Industries, 1-1, Wadasaki-cho 1-chome, Hyogo-ku, Kobe (Japan); Choi, C.H.; Utin, Y.; Sborchia, C. [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France); TaiLhardat, O. [Assystem EOS, ZAC SAINT MARTIN, 23 rue Benjamin Franklin, 84120 Pertuis (France); Mille, B.; Terasawa, A.; Gribov, Y.; Barabash, V.; Polunovskiy, E.; Dani, S. [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France); Pathak, H.; Raval, J. [ITER-India, Institute for Plasma Research, Gandhinagar 382025 (India); Liu, S.; Lu, M.; Du, S. [Institute of Plasma Physics, China Academy of Sciences, Shushanhu Road 350, Hefei (China)

    2014-10-15

    The ITER vacuum vessel is a torus-shaped, double wall structure. The space between the double walls of the VV is filled with in-wall shielding (IWS) and cooling water. The main purpose of the in-wall shielding is to provide neutron shielding together with the blanket and VV shells and water during ITER plasma operation and to reduce the ripple of the Toroidal magnetic field. Based on ITER vacuum vessel structure and related requirements, in-wall shielding are designed as about 8900 individual blocks with different sizes and several different materials distributed over nine vessel sectors and nine field joints of vessel sectors. This paper presents the design of the IWS, considering loads, structural stresses and assembly method, and also shows neutron shielding effect and TF ripple reduced by the IWS.

  18. Plasma engineering and electromagnetic aspects in ITER design

    Energy Technology Data Exchange (ETDEWEB)

    Albanese, R. [Consorzio CREATE, Dipt. di Ingegneria Elettrica, Napoli (Italy); Ambrosino, G. [Consorzio CREATE, Dipt. di Ingegneria Elettrica, Napoli (Italy); Bottura, L. [NET Team, Garching (Germany); Coccorese, E. [Consorzio CREATE, Dipt. di Ingegneria Elettrica, Napoli (Italy); Formisano, A. [Consorzio CREATE, Dipt. di Ingegneria Elettrica, Napoli (Italy); Fresa, R. [Consorzio CREATE, Dipt. di Ingegneria Elettrica, Napoli (Italy); Garofalo, F. [Consorzio CREATE, Dipt. di Ingegneria Elettrica, Napoli (Italy); Morabito, C. [Consorzio CREATE, Dipt. di Ingegneria Elettrica, Napoli (Italy); Pironti, A. [Consorzio CREATE, Dipt. di Ingegneria Elettrica, Napoli (Italy); Martone, R. [Consorzio CREATE, Dipt. di Ingegneria Elettrica, Napoli (Italy); Rubinacci, G. [Consorzio CREATE, Dipt. di Ingegneria Elettrica, Napoli (Italy); Scala, S. [Consorzio CREATE, Dipt. di Ingegneria Elettrica, Napoli (Italy); Ventre, S. [Consorzio CREATE, Dipt. di Ingegneria Elettrica, Napoli (Italy)

    1995-12-31

    The paper deals with the main electromagnetic problems currently being considered for their impact on the ITER project. A central role is played by the plasma scenario, whose optimisation requires fulfilment of physic requirements in presence of PF coil current and voltage limitations. A critical issue is the stabilisation of the elongated plasma; this is performed via a suitable control system, whose promptness, robustness, power requirements and side effects on the other conducting structures has to be carefully assessed. Plasma equilibria are significantly affected by the axisymmetric component of the eddy current flowing in the metallic structure during transient phases; moreover, eddy currents have to be considered in their 3D nature when assessing electromechanic stress and Joule losses in the cold structures. The paper reports a selection of predictive computations referred to a proposed ITER configuration, aiming to contribute to the definition of the ITER design guidelines. (orig.).

  19. The ITER Radial Neutron Camera Detection System

    Science.gov (United States)

    Marocco, D.; Belli, F.; Bonheure, G.; Esposito, B.; Kaschuck, Y.; Petrizzi, L.; Riva, M.

    2008-03-01

    A multichannel neutron detection system (Radial Neutron Camera, RNC) will be installed on the ITER equatorial port plug 1 for total neutron source strength, neutron emissivity/ion temperature profiles and nt/nd ratio measurements [1]. The system is composed by two fan shaped collimating structures: an ex-vessel structure, looking at the plasma core, containing tree sets of 12 collimators (each set lying on a different toroidal plane), and an in-vessel structure, containing 9 collimators, for plasma edge coverage. The RNC detecting system will work in a harsh environment (neutron fiux up to 108-109 n/cm2 s, magnetic field >0.5 T or in-vessel detectors), should provide both counting and spectrometric information and should be flexible enough to cover the high neutron flux dynamic range expected during the different ITER operation phases. ENEA has been involved in several activities related to RNC design and optimization [2,3]. In the present paper the up-to-date design and the neutron emissivity reconstruction capabilities of the RNC will be described. Different options for detectors suitable for spectrometry and counting (e.g. scintillators and diamonds) focusing on the implications in terms of overall RNC performance will be discussed. The increase of the RNC capabilities offered by the use of new digital data acquisition systems will be also addressed.

  20. Bounded Fixed-Point Iteration

    DEFF Research Database (Denmark)

    Nielson, Hanne Riis; Nielson, Flemming

    1992-01-01

    they obtain a quadratic bound. These bounds are shown to be tight. Specializing the case of strict and additive functions to functionals of a form that would correspond to iterative programs they show that a linear bound is tight. This is related to several analyses studied in the literature (including...

  1. Iterative method for interferogram processing

    Science.gov (United States)

    Kotlyar, Victor V.; Seraphimovich, P. G.; Zalyalov, Oleg K.

    1994-12-01

    We have developed and numerically evaluated an iterative algorithm for interferogram processing including the Fourier-transform method, the Gerchberg-Papoulis algorithm and Wiener's filter-based regularization used in combination. Using a signal-to-noise ratio not less than 1, it has been possible to reconstruct the phase of an object field with accuracy better than 5%.

  2. Energetic ions in ITER plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Pinches, S. D. [ITER Organization, Route de Vinon-sur-Verdon, CS 90 046, 13067 St Paul-lez-Durance Cedex (France); Chapman, I. T.; Sharapov, S. E. [CCFE, Culham Science Centre, Abingdon, Oxfordshire OX14 3DB (United Kingdom); Lauber, Ph. W. [Max-Planck-Institut für Plasmaphysik, EURATOM-Association, Boltzmanstraße 2, D-85748 Garching (Germany); Oliver, H. J. C. [H H Wills Physics Laboratory, University of Bristol, Royal Fort, Tyndall Avenue, Bristol BS8 1TL (United Kingdom); CCFE, Culham Science Centre, Abingdon, Oxfordshire OX14 3DB (United Kingdom); Shinohara, K. [Japan Atomic Energy Agency, Naka, Ibaraki 311-0193 (Japan); Tani, K. [Nippon Advanced Technology Co., Ltd, Naka, Ibaraki 311-0102 (Japan)

    2015-02-15

    This paper discusses the behaviour and consequences of the expected populations of energetic ions in ITER plasmas. It begins with a careful analytic and numerical consideration of the stability of Alfvén Eigenmodes in the ITER 15 MA baseline scenario. The stability threshold is determined by balancing the energetic ion drive against the dominant damping mechanisms and it is found that only in the outer half of the plasma (r/a>0.5) can the fast ions overcome the thermal ion Landau damping. This is in spite of the reduced numbers of alpha-particles and beam ions in this region but means that any Alfvén Eigenmode-induced redistribution is not expected to influence the fusion burn process. The influence of energetic ions upon the main global MHD phenomena expected in ITER's primary operating scenarios, including sawteeth, neoclassical tearing modes and Resistive Wall Modes, is also reviewed. Fast ion losses due to the non-axisymmetric fields arising from the finite number of toroidal field coils, the inclusion of ferromagnetic inserts, the presence of test blanket modules containing ferromagnetic material, and the fields created by the Edge Localised Mode (ELM) control coils in ITER are discussed. The greatest losses and associated heat loads onto the plasma facing components arise due to the use of the ELM control coils and come from neutral beam ions that are ionised in the plasma edge.

  3. Energetic ions in ITER plasmas

    Science.gov (United States)

    Pinches, S. D.; Chapman, I. T.; Lauber, Ph. W.; Oliver, H. J. C.; Sharapov, S. E.; Shinohara, K.; Tani, K.

    2015-02-01

    This paper discusses the behaviour and consequences of the expected populations of energetic ions in ITER plasmas. It begins with a careful analytic and numerical consideration of the stability of Alfvén Eigenmodes in the ITER 15 MA baseline scenario. The stability threshold is determined by balancing the energetic ion drive against the dominant damping mechanisms and it is found that only in the outer half of the plasma ( r / a > 0.5 ) can the fast ions overcome the thermal ion Landau damping. This is in spite of the reduced numbers of alpha-particles and beam ions in this region but means that any Alfvén Eigenmode-induced redistribution is not expected to influence the fusion burn process. The influence of energetic ions upon the main global MHD phenomena expected in ITER's primary operating scenarios, including sawteeth, neoclassical tearing modes and Resistive Wall Modes, is also reviewed. Fast ion losses due to the non-axisymmetric fields arising from the finite number of toroidal field coils, the inclusion of ferromagnetic inserts, the presence of test blanket modules containing ferromagnetic material, and the fields created by the Edge Localised Mode (ELM) control coils in ITER are discussed. The greatest losses and associated heat loads onto the plasma facing components arise due to the use of the ELM control coils and come from neutral beam ions that are ionised in the plasma edge.

  4. Iterative Specialisation of Horn Clauses

    DEFF Research Database (Denmark)

    Nielsen, Christoffer Rosenkilde; Nielson, Flemming; Nielson, Hanne Riis

    2008-01-01

    We present a generic algorithm for solving Horn clauses through iterative specialisation. The algorithm is generic in the sense that it can be instantiated with any decidable fragment of Horn clauses, resulting in a solution scheme for general Horn clauses that guarantees soundness and terminatio...

  5. Cooperation between CERN and ITER

    CERN Multimedia

    CERN Audiovisual Service

    2008-01-01

    CERN and the International Fusion Organisation ITER have just signed a first cooperation agreeement. The Director-General of the International Fusion Energy Organization, Mr Kaname Ikeda, and CERN Director-General, Robert Aymar, signed a cooperation agreement at a meeting on the Meyrin site on Thursday 6 March.

  6. Development and study of a parallel algorithm of iteratively forming latent functionally-determined structures for classification and analysis of meteorological data

    Science.gov (United States)

    Sorokin, V. A.; Volkov, Yu V.; Sherstneva, A. I.; Botygin, I. A.

    2016-11-01

    This paper overviews a method of generating climate regions based on an analytic signal theory. When applied to atmospheric surface layer temperature data sets, the method allows forming climatic structures with the corresponding changes in the temperature to make conclusions on the uniformity of climate in an area and to trace the climate changes in time by analyzing the type group shifts. The algorithm is based on the fact that the frequency spectrum of the thermal oscillation process is narrow-banded and has only one mode for most weather stations. This allows using the analytic signal theory, causality conditions and introducing an oscillation phase. The annual component of the phase, being a linear function, was removed by the least squares method. The remaining phase fluctuations allow consistent studying of their coordinated behavior and timing, using the Pearson correlation coefficient for dependence evaluation. This study includes program experiments to evaluate the calculation efficiency in the phase grouping task. The paper also overviews some single-threaded and multi-threaded computing models. It is shown that the phase grouping algorithm for meteorological data can be parallelized and that a multi-threaded implementation leads to a 25-30% increase in the performance.

  7. Active beam spectroscopy for ITER

    Energy Technology Data Exchange (ETDEWEB)

    Hellermann, M.G. von, E-mail: mgvh@jet.u [FOM Institute Rijnhuizen, Euratom Association, 3430BE Nieuwegein (Netherlands); Barnsley, R. [ITER Organization, 13108 St.-Paul-Lez-Durance, Cadarache (France); Biel, W. [Institut fuer Energieforschung, Plasmaphysik, Forschungszentrum Juelich, Euratom Association, 52425 Juelich (Germany); Delabie, E. [FOM Institute Rijnhuizen, Euratom Association, 3430BE Nieuwegein (Netherlands); Hawkes, N. [Culham Centre for Fusion Energy, Euratom Association, Culham OX14 3DB (United Kingdom); Jaspers, R. [FOM Institute Rijnhuizen, Euratom Association, 3430BE Nieuwegein (Netherlands); Johnson, D. [Princeton Plasma Physics Laboratory, Princeton, NJ-08548 (United States); Klinkhamer, F. [TNO Science and Industry, Stieltjesweg 1, 2628CK Delft (Netherlands); Lischtschenko, O. [FOM Institute Rijnhuizen, Euratom Association, 3430BE Nieuwegein (Netherlands); Marchuk, O. [Institut fuer Energieforschung, Plasmaphysik, Forschungszentrum Juelich, Euratom Association, 52425 Juelich (Germany); Schunke, B. [ITER Organization, 13108 St.-Paul-Lez-Durance, Cadarache (France); Singh, M.J. [Institute for Plasma Research, Bhat, Gandhinagar, Gurajat 384828 (India); Snijders, B. [TNO Science and Industry, Stieltjesweg 1, 2628CK Delft (Netherlands); Summers, H.P. [Culham Centre for Fusion Energy, Euratom Association, Culham OX14 3DB (United Kingdom); Thomas, D. [ITER Organization, 13108 St.-Paul-Lez-Durance, Cadarache (France); Tugarinov, S. [TRINITI Troitsk, Moscow Region 142092 (Russian Federation); Vasu, P. [Institute for Plasma Research, Bhat, Gandhinagar, Gurajat 384828 (India)

    2010-11-11

    Since the first feasibility studies of active beam spectroscopy on ITER in 1995 the proposed diagnostic has developed into a well advanced and mature system. Substantial progress has been achieved on the physics side including comprehensive performance studies based on an advanced predictive code, which simulates active and passive features of the expected spectral ranges. The simulation has enabled detailed specifications for an optimized instrumentation and has helped to specify suitable diagnostic neutral beam parameters. Four ITER partners share presently the task of developing a suite of ITER active beam diagnostics, which make use of the two 0.5 MeV/amu 18 MW heating neutral beams and a dedicated 0.1 MeV/amu, 3.6 MW diagnostic neutral beam. The IN ITER team is responsible for the DNB development and also for beam physics related aspects of the diagnostic. The RF will be responsible for edge CXRS system covering the outer region of the plasma (1>r/a>0.4) using an equatorial observation port, and the EU will develop the core CXRS system for the very core (0ITER environment. Additionally, an essential change of the orientation of the DNB injection angle and specification of suitable blanket aperture has been made to avoid trapped particle damage to the first wall.

  8. Engineering and manufacturing of ITER first mirror mock-ups.

    Science.gov (United States)

    Joanny, M; Travère, J M; Salasca, S; Corre, Y; Marot, L; Thellier, C; Gallay, G; Cammarata, C; Passier, B; Fermé, J J

    2010-10-01

    Most of the ITER optical diagnostics aiming at viewing and monitoring plasma facing components will use in-vessel metallic mirrors. These mirrors will be exposed to a severe plasma environment and lead to an important tradeoff on their design and manufacturing. As a consequence, investigations are carried out on diagnostic mirrors toward the development of optimal and reliable solutions. The goals are to assess the manufacturing feasibility of the mirror coatings, evaluate the manufacturing capability and associated performances for the mirrors cooling and polishing, and finally determine the costs and delivery time of the first prototypes with a diameter of 200 and 500 mm. Three kinds of ITER candidate mock-ups are being designed and manufactured: rhodium films on stainless steel substrate, molybdenum on TZM substrate, and silver films on stainless steel substrate. The status of the project is presented in this paper.

  9. Identification of candidate gene regions in the rat by co-localization of QTLs for bone density, size, structure and strength.

    Directory of Open Access Journals (Sweden)

    Sofia Lagerholm

    Full Text Available Susceptibility to osteoporotic fracture is influenced by genetic factors that can be dissected by whole-genome linkage analysis in experimental animal crosses. The aim of this study was to characterize quantitative trait loci (QTLs for biomechanical and two-dimensional dual-energy X-ray absorptiometry (DXA phenotypes in reciprocal F2 crosses between diabetic GK and normo-glycemic F344 rat strains and to identify possible co-localization with previously reported QTLs for bone size and structure. The biomechanical measurements of rat tibia included ultimate force, stiffness and work to failure while DXA was used to characterize tibial area, bone mineral content (BMC and areal bone mineral density (aBMD. F2 progeny (108 males, 98 females were genotyped with 192 genome-wide markers followed by sex- and reciprocal cross-separated whole-genome QTL analyses. Significant QTLs were identified on chromosome 8 (tibial area; logarithm of odds (LOD = 4.7 and BMC; LOD = 4.1 in males and on chromosome 1 (stiffness; LOD = 5.5 in females. No QTLs showed significant sex-specific interactions. In contrast, significant cross-specific interactions were identified on chromosome 2 (aBMD; LOD = 4.7 and chromosome 6 (BMC; LOD = 4.8 for males carrying F344mtDNA, and on chromosome 15 (ultimate force; LOD = 3.9 for males carrying GKmtDNA, confirming the effect of reciprocal cross on osteoporosis-related phenotypes. By combining identified QTLs for biomechanical-, size- and qualitative phenotypes (pQCT and 3D CT from the same population, overlapping regions were detected on chromosomes 1, 3, 4, 6, 8 and 10. These are strong candidate regions in the search for genetic risk factors for osteoporosis.

  10. ITERATIVE ALGORITHMS FOR DATA ASSIMILATION PROBLEMS

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Iterative algorithms for solving the data assimilation problems are considered, based on the main and adjoint equations. Spectral properties of the control operators of the problem are studied, the iterative algorithms are justified.

  11. Existence test for asynchronous interval iterations

    DEFF Research Database (Denmark)

    Madsen, Kaj; Caprani, O.; Stauning, Ole

    1997-01-01

    In the search for regions that contain fixed points ofa real function of several variables, tests based on interval calculationscan be used to establish existence ornon-existence of fixed points in regions that are examined in the course ofthe search. The search can e.g. be performed...... as a synchronous (sequential) interval iteration:In each iteration step all components of the iterate are calculatedbased on the previous iterate. In this case it is straight forward to base simple interval existence and non-existencetests on the calculations done in each step of the iteration. The search can also...... be performed as an asynchronous (parallel) iteration: Only a few components are changed in each stepand this calculation is in general based on components from differentprevious iterates. For the asynchronous iteration it turns out thatsimple tests of existence and non-existence can be based...

  12. Evaluating ITER remote handling middleware concepts

    Energy Technology Data Exchange (ETDEWEB)

    Koning, J.F., E-mail: j.f.koning@differ.nl [FOM Institute DIFFER, Association EURATOM-FOM, Partner in the Trilateral Euregio Cluster and ITER-NL, PO Box 1207, 3430 BE Nieuwegein (Netherlands); Heemskerk, C.J.M.; Schoen, P.; Smedinga, D. [Heemskerk Innovative Technology, Noordwijk (Netherlands); Boode, A.H. [University of Applied Sciences InHolland, Alkmaar (Netherlands); Hamilton, D.T. [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France)

    2013-10-15

    Highlights: ► Remote Handling Study Centre: middleware system setup and modules built. ► Aligning to ITER RH Control System Layout: prototype of database, VR and simulator. ► OpenSplice DDS, ZeroC ICE messaging and object oriented middlewares reviewed. ► Windows network latency found problematic for semi-realtime control over the network. -- Abstract: Remote maintenance activities in ITER will be performed by a unique set of hardware systems, supported by an extensive software kit. A layer of middleware will manage and control a complex set of interconnections between teams of operators, hardware devices in various operating theatres, and databases managing tool and task logistics. The middleware is driven by constraints on amounts and timing of data like real-time control loops, camera images, and database access. The Remote Handling Study Centre (RHSC), located at FOM institute DIFFER, has a 4-operator work cell in an ITER relevant RH Control Room setup which connects to a virtual hot cell back-end. The centre is developing and testing flexible integration of the Control Room components, resulting in proof-of-concept tests of this middleware layer. SW components studied include generic human-machine interface software, a prototype of a RH operations management system, and a distributed virtual reality system supporting multi-screen, multi-actor, and multiple independent views. Real-time rigid body dynamics and contact interaction simulation software supports simulation of structural deformation, “augmented reality” operations and operator training. The paper presents generic requirements and conceptual design of middleware components and Operations Management System in the context of a RH Control Room work cell. The simulation software is analyzed for real-time performance and it is argued that it is critical for middleware to have complete control over the physical network to be able to guarantee bandwidth and latency to the components.

  13. Independent candidates in Mexico

    OpenAIRE

    Campos, Gonzalo Santiago

    2014-01-01

    In this paper we discuss the issue of independent candidates in Mexico, because through the so-called political reform of 2012 was incorporated in the Political Constitution of the Mexican United States the right of citizens to be registered as independent candidates. Also, in September 2013 was carried out a reform of Article 116 of the Political Constitution of the Mexican United States in order to allow independent candidates in each state of the Republic. However, prior to the constitutio...

  14. REMARK ON STABILITY OF ISHIKAWA ITERATIVE PROCEDURES

    Institute of Scientific and Technical Information of China (English)

    薛志群; 田虹

    2002-01-01

    The stability of the Ishikawa iteration procedures was studied for one class ofcontinuity strong pseudocontraction and continuity strongly accretive operators with boundedrange in real uniformly smooth Banach space. Under parameters satisfying certainconditions, the convergence of iterative sequences was proved. The results improve andextend the recent corresponding results, and supply the basis of theory for further discussingconvergence of iteration procedures with errors.

  15. An Iterative Rejection Sampling Method

    CERN Document Server

    Sherstnev, A

    2008-01-01

    In the note we consider an iterative generalisation of the rejection sampling method. In high energy physics, this sampling is frequently used for event generation, i.e. preparation of phase space points distributed according to a matrix element squared $|M|^2$ for a scattering process. In many realistic cases $|M|^2$ is a complicated multi-dimensional function, so, the standard von Neumann procedure has quite low efficiency, even if an error reducing technique, like VEGAS, is applied. As a result of that, many of the $|M|^2$ calculations go to ``waste''. The considered iterative modification of the procedure can extract more ``unweighted'' events, i.e. distributed according to $|M|^2$. In several simple examples we show practical benefits of the technique and obtain more events than the standard von Neumann method, without any extra calculations of $|M|^2$.

  16. Matlab modeling of ITER CODAC

    Energy Technology Data Exchange (ETDEWEB)

    Pangione, L. [Associazione Euratom/ENEA Ssulla Fusione, Centro Ricerche Frascati, CP 65, 00044 Frascati, Roma (Italy)], E-mail: pangione@frascati.enea.it; Lister, J.B. [CRPP-EPFL, Association EURATOM-Suisse, Station 13, 1015 Lausanne (Switzerland)

    2008-04-15

    The ITER CODAC (COntrol, Data Access and Communication) conceptual design resulted from 2 years of activity. One result was a proposed functional partitioning of CODAC into different CODAC Systems, each of them partitioned into other CODAC Systems. Considering the large size of this project, simple use of human language assisted by figures would certainly be ineffective in creating an unambiguous description of all interactions and all relations between these Systems. Moreover, the underlying design is resident in the mind of the designers, who must consider all possible situations that could happen to each system. There is therefore a need to model the whole of CODAC with a clear and preferably graphical method, which allows the designers to verify the correctness and the consistency of their project. The aim of this paper is to describe the work started on ITER CODAC modeling using Matlab/Simulink. The main feature of this tool is the possibility of having a simple, graphical, intuitive representation of a complex system and ultimately to run a numerical simulation of it. Using Matlab/Simulink, each CODAC System was represented in a graphical and intuitive form with its relations and interactions through the definition of a small number of simple rules. In a Simulink diagram, each system was represented as a 'black box', both containing, and connected to, a number of other systems. In this way it is possible to move vertically between systems on different levels, to show the relation of membership, or horizontally to analyse the information exchange between systems at the same level. This process can be iterated, starting from a global diagram, in which only CODAC appears with the Plant Systems and the external sites, and going deeper down to the mathematical model of each CODAC system. The Matlab/Simulink features for simulating the whole top diagram encourage us to develop the idea of completing the functionalities of all systems in order to finally

  17. Iterative Goal Refinement for Robotics

    Science.gov (United States)

    2014-06-01

    Iterative Goal Refinement for Robotics Mark Roberts1, Swaroop Vattam1, Ronald Alford2, Bryan Auslander3, Justin Karneeb3, Matthew Molineaux3... robotics researchers and practitioners. We present a goal lifecycle and define a formal model for GR that (1) relates distinct disciplines concerning...researchers to collaborate in exploring this exciting frontier. 1. Introduction Robotic systems often act using incomplete models in environments

  18. Truncated States Obtained by Iteration

    Institute of Scientific and Technical Information of China (English)

    W.B.Cardoso; N.G.de Almeida

    2008-01-01

    We introduce the concept of truncated states obtained via iterative processes(TSI)and study its statistical features,making an analogy with dynamical systems theory(DST).As a specific example,we have studied TSI for the doubring and the logistic functions,which are standard functions in studying chaos.TSI for both the doubling and logistic functions exhibit certain similar patterns when their statistical features are compared from the point of view of DST.

  19. Direct Waveform Inversion by Iterative Inverse Propagation

    CERN Document Server

    Schlottmann, R B

    2009-01-01

    Seismic waves are the most sensitive probe of the Earth's interior we have. With the dense data sets available in exploration, images of subsurface structures can be obtained through processes such as migration. Unfortunately, relating these surface recordings to actual Earth properties is non-trivial. Tomographic techniques use only a small amount of the information contained in the full seismogram and result in relatively low resolution images. Other methods use a larger amount of the seismogram but are based on either linearization of the problem, an expensive statistical search over a limited range of models, or both. We present the development of a new approach to full waveform inversion, i.e., inversion which uses the complete seismogram. This new method, which falls under the general category of inverse scattering, is based on a highly non-linear Fredholm integral equation relating the Earth structure to itself and to the recorded seismograms. An iterative solution to this equation is proposed. The res...

  20. ITER coils insulation R and D program

    Energy Technology Data Exchange (ETDEWEB)

    Vieira, R.F.; Sugimoto, M.; Osaki, O.; Fujioka, T.; Korsunsky, V.; Reed, R.P.; Katheder, H.; Broadbent, A.

    1995-12-31

    The ITER coil insulation systems are required for operating voltages up to 10 KV and to support shear and normal compression loads through the winding pack. Manufacturing considerations and nuclear radiation resistance also influence the choice of suitable systems. A screening program of candidate systems is being conducted in stages. The first stage is reported in this paper. Present R and D data based on small samples indicate a static shear strength of about 85 MPa for a glass or alumina and epoxy resin vacuum pressure impregnation system and 50 MPa for a pre-impregnated glass/epoxy resin system with polyimide interleaved at a temperature of 4K. The preliminary irradiation results show that coating the steel surface with inorganic materials such as Al{sub 2}O{sub 3} or ZrO{sub 2}/8 Y{sub 2}O{sub 3} is beneficial in increasing the radiation resistance as far as shear strength is concerned. In addition Tetrafunctional epoxy (TGDM) systems appear to be more radiation resistant than Diglycidyl Ether of Bisphenol-A (DGEBA) systems. Further R and D work will focus on prototypical samples to continue evaluation of the performance of the insulation systems.

  1. A Dynamic Assignment of Extrinsic Information Distribution by a Frequency Means for Iterative Turbo Decoder

    Institute of Scientific and Technical Information of China (English)

    YANGFengfan

    2003-01-01

    In this paper, a new strategy for iterative turbo decoding is proposed, where a Generalized Gaussian distribution (GGD) is applied to model the statistical distributions of the extrinsic information generated by the component decoders. An Euclidean distance criterion is also introduced to choose a most likely candidate of the extrinsic information distribution before the each constituent decoding by a novel frequency means. The simulation results show that performance of an iterative decoder with this new technique surpasses the conventional Gaussian solution for the extrinsic information under the same channel conditions. Meanwhile, the evolution process of the extrinsic information density function can be tracked from iteration to iteration in the sense of the proposed criterion.

  2. Radioactivity measurements of ITER materials using the TFTR D-T neutron field

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, A.; Abdou, M.A. [California Univ., Los Angeles, CA (United States). School of Engineering and Applied Science; Barnes, C.W. [Los Alamos National Lab., NM (United States); Kugel, H.W. [Princeton Univ., NJ (United States). Plasma Physics Lab.; Loughlin, M.J. [Commission of the European Communities, Abingdon (United Kingdom). JET Joint Undertaking

    1994-08-01

    The availability of high D-T fusion neutron yields at TFTR has provided a useful opportunity to directly measure D-T neutron-induced radioactivity in a realistic tokamak fusion reactor environment for materials of vital interest to ITER. These measurements are valuable for characterizing radioactivity in various ITER candidate materials. for validating complex neutron transport calculations, and for meeting fusion reactor licensing requirements. The radioactivity measurements at TFTR involve potential ITER materials including stainless steel 316, vanadium, titanium, chromium, silicon, iron, cobalt, nickel, molybdenum, aluminum, copper, zinc. zirconium, niobium, and tungsten. Small samples of these materials were irradiated close to the plasma and just outside the vacuum vessel wall of TFTR, locations of different neutron energy spectra. Saturation activities for both threshold and capture reactions were measured. Data from dosimetric reactions have been used to obtain preliminary neutron energy spectra. Spectra from the first wall were compared to calculations from ITER and to measurements from accelerator-based tests.

  3. Weighted thinned linear array design with the iterative FFT technique

    CSIR Research Space (South Africa)

    Du Plessis, WP

    2011-09-01

    Full Text Available A version of the iterative Fourier technique (IFT) for the design of thinned antenna arrays with weighted elements is presented. The structure of the algorithm means that it is well suited to the design of weighted thinned arrays with low current...

  4. Meromorphic iterative roots of linear fractional functions

    Institute of Scientific and Technical Information of China (English)

    SHI YongGuo; CHEN Li

    2009-01-01

    Iterative root problem can be regarded as a weak version of the problem of embedding a homeomorphism into a flow. There are many results on iterative roots of monotone functions. However, this problem gets more difficult in non-monotone cases. Therefore, it is interesting to find iterative roots of linear fractional functions (abbreviated as LFFs), a class of non-monotone functions on R. In this paper, iterative roots of LFFs are studied on C. An equivalence between the iterative functional equation for non-constant LFFs and the matrix equation is given. By means of a method of finding matrix roots, general formulae of all meromorphic iterative roots of LFFs are obtained and the precise number of roots is also determined in various cases. As applications, we present all meromorphic iterative roots for functions z and 1/z.

  5. Performance bounds for Lambda Policy Iteration

    CERN Document Server

    Scherrer, Bruno

    2007-01-01

    We consider the discrete-time infinite-horizon discounted stationary optimal control problem formalized by Markov Decision Processes. We study Lambda Policy Iteration, a family of algorithms parameterized by lambda, originally introduced by Ioffe and Bertsekas. Lambda Policy Iteration generalizes the standard algorithms Value Iteration and Policy Iteration, and has some connections with TD(Lambda) introduced by Sutton & Barto. We deepen the original theory developped by Ioffe and Bertsekas by providing convergence rate bounds which generalize standard bounds for Value Iteration described for instance by Puterman. We also develop the theory of this algorithm when it is used in an approximate form. Doing so, we extend and unify the separate analyses developped by Munos for Approximate Value Iteration and Approximate Policy Iteration.

  6. The prospect for fuel ion ratio measurements in ITER by collective Thomson scattering

    DEFF Research Database (Denmark)

    Stejner Pedersen, Morten; Korsholm, Søren Bang; Nielsen, Stefan Kragh

    2012-01-01

    We show that collective Thomson scattering (CTS) holds the potential to become a new diagnostic principle for measurements of the fuel ion ratio, nT/nD, in ITER. Fuel ion ratio measurements will be important for plasma control and machine protection in ITER. Measurements of ion cyclotron structures...

  7. Development of design Criteria for ITER In-vessel Components

    Energy Technology Data Exchange (ETDEWEB)

    Sannazzaro, G., E-mail: Giulio.Sannazzaro@iter.org [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France); Barabash, V.; Kang, S.C. [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France); Fernandez, E. [Fusion For Energy, Josep Pla, 2, Torres Diagonal Mar B3, 08019 Barcelona (Spain); Kalinin, G.; Obushev, A. [The Research and Development Institute of Power Engineering, P.O. Box 788, Moscow (Russian Federation); Martínez, V.J.; Vázquez, I. [IDESA, Parque Científico Tecnológico, C/Profesor Potter 105, 33203 Gijón (Spain); Fernández, F.; Guirao, J. [NATEC, C/Marqués de San Esteban 52 Entlo, 33209 Gijón (Spain)

    2013-10-15

    Absrtract: The components located inside the ITER vacuum chamber (in-vessel components – IC), due to their specific nature and the environments they are exposed to (neutron radiation, high heat fluxes, electromagnetic forces, etc.), have specific design criteria which are, in this paper, referred as Structural Design Criteria for In-vessel Components (SDC-IC). The development of these criteria started in the very early phase of the ITER design and followed closely the criteria of the RCC-MR code. Specific rules to include the effect of neutron irradiation were implemented. In 2008 the need of an update of the SDC-IC was identified to add missing specifications, to implement improvements, to modernise rules including recent evolutions in international codes and regulations (i.e. PED). Collaboration was set up between ITER Organization (IO), European (EUDA) and Russian Federation (RFDA) Domestic Agencies to generate a new version of SDC-IC. A Peer Review Group (PRG) composed by members of the ITER Organization and all ITER Domestic Agencies and code experts was set-up to review the proposed modifications, to provide comments, contributions and recommendations.

  8. Topological quantum gate construction by iterative pseudogroup hashing

    Science.gov (United States)

    Burrello, Michele; Mussardo, Giuseppe; Wan, Xin

    2011-02-01

    We describe the hashing technique for obtaining a fast approximation of a target quantum gate in the unitary group SU(2) represented by a product of the elements of a universal basis. The hashing exploits the structure of the icosahedral group (or other finite subgroups of SU(2)) and its pseudogroup approximations to reduce the search within a small number of elements. One of the main advantages of the pseudogroup hashing is the possibility of iterating to obtain more accurate representations of the targets in the spirit of the renormalization group approach. We describe the iterative pseudogroup hashing algorithm using the universal basis given by the braidings of Fibonacci anyons. An analysis of the efficiency of the iterations based on the random matrix theory indicates that the runtime and braid length scale poly-logarithmically with the final error, comparing favorably to the Solovay-Kitaev algorithm.

  9. Natural Preconditioning and Iterative Methods for Saddle Point Systems

    KAUST Repository

    Pestana, Jennifer

    2015-01-01

    © 2015 Society for Industrial and Applied Mathematics. The solution of quadratic or locally quadratic extremum problems subject to linear(ized) constraints gives rise to linear systems in saddle point form. This is true whether in the continuous or the discrete setting, so saddle point systems arising from the discretization of partial differential equation problems, such as those describing electromagnetic problems or incompressible flow, lead to equations with this structure, as do, for example, interior point methods and the sequential quadratic programming approach to nonlinear optimization. This survey concerns iterative solution methods for these problems and, in particular, shows how the problem formulation leads to natural preconditioners which guarantee a fast rate of convergence of the relevant iterative methods. These preconditioners are related to the original extremum problem and their effectiveness - in terms of rapidity of convergence - is established here via a proof of general bounds on the eigenvalues of the preconditioned saddle point matrix on which iteration convergence depends.

  10. Topological quantum gate construction by iterative pseudogroup hashing

    Energy Technology Data Exchange (ETDEWEB)

    Burrello, Michele; Mussardo, Giuseppe [International School for Advanced Studies (SISSA), Via Bonomea 265, 34136 Trieste (Italy); Wan Xin, E-mail: burrello@sissa.it, E-mail: mussardo@sissa.it [Asia Pacific Center for Theoretical Physics, Pohang, Gyeongbuk 790-784 (Korea, Republic of)

    2011-02-15

    We describe the hashing technique for obtaining a fast approximation of a target quantum gate in the unitary group SU(2) represented by a product of the elements of a universal basis. The hashing exploits the structure of the icosahedral group (or other finite subgroups of SU(2)) and its pseudogroup approximations to reduce the search within a small number of elements. One of the main advantages of the pseudogroup hashing is the possibility of iterating to obtain more accurate representations of the targets in the spirit of the renormalization group approach. We describe the iterative pseudogroup hashing algorithm using the universal basis given by the braidings of Fibonacci anyons. An analysis of the efficiency of the iterations based on the random matrix theory indicates that the runtime and braid length scale poly-logarithmically with the final error, comparing favorably to the Solovay-Kitaev algorithm.

  11. Recent progress and advances in iterative software (including parallel aspects)

    Energy Technology Data Exchange (ETDEWEB)

    Carey, G.; Young, D.M.; Kincaid, D. [and others

    1994-12-31

    The purpose of the workshop is to provide a forum for discussion of the current state of iterative software packages. Of particular interest is software for large scale engineering and scientific applications, especially for distributed parallel systems. However, the authors will also review the state of software development for conventional architectures. This workshop will complement the other proposed workshops on iterative BLAS kernels and applications. The format for the workshop is as follows: To provide some structure, there will be brief presentations, each of less than five minutes duration and dealing with specific facets of the subject. These will be designed to focus the discussion and to stimulate an exchange with the participants. Issues to be covered include: The evolution of iterative packages, current state of the art, the parallel computing challenge, applications viewpoint, standards, and future directions and open problems.

  12. Migration of vectorized iterative solvers to distributed memory architectures

    Energy Technology Data Exchange (ETDEWEB)

    Pommerell, C. [AT& T Bell Labs., Murray Hill, NJ (United States); Ruehl, R. [CSCS-ETH, Manno (Switzerland)

    1994-12-31

    Both necessity and opportunity motivate the use of high-performance computers for iterative linear solvers. Necessity results from the size of the problems being solved-smaller problems are often better handled by direct methods. Opportunity arises from the formulation of the iterative methods in terms of simple linear algebra operations, even if this {open_quote}natural{close_quotes} parallelism is not easy to exploit in irregularly structured sparse matrices and with good preconditioners. As a result, high-performance implementations of iterative solvers have attracted a lot of interest in recent years. Most efforts are geared to vectorize or parallelize the dominating operation-structured or unstructured sparse matrix-vector multiplication, or to increase locality and parallelism by reformulating the algorithm-reducing global synchronization in inner products or local data exchange in preconditioners. Target architectures for iterative solvers currently include mostly vector supercomputers and architectures with one or few optimized (e.g., super-scalar and/or super-pipelined RISC) processors and hierarchical memory systems. More recently, parallel computers with physically distributed memory and a better price/performance ratio have been offered by vendors as a very interesting alternative to vector supercomputers. However, programming comfort on such distributed memory parallel processors (DMPPs) still lags behind. Here the authors are concerned with iterative solvers and their changing computing environment. In particular, they are considering migration from traditional vector supercomputers to DMPPs. Application requirements force one to use flexible and portable libraries. They want to extend the portability of iterative solvers rather than reimplementing everything for each new machine, or even for each new architecture.

  13. Cryogenic instrumentation for ITER magnets

    Science.gov (United States)

    Poncet, J.-M.; Manzagol, J.; Attard, A.; André, J.; Bizel-Bizellot, L.; Bonnay, P.; Ercolani, E.; Luchier, N.; Girard, A.; Clayton, N.; Devred, A.; Huygen, S.; Journeaux, J.-Y.

    2017-02-01

    Accurate measurements of the helium flowrate and of the temperature of the ITER magnets is of fundamental importance to make sure that the magnets operate under well controlled and reliable conditions, and to allow suitable helium flow distribution in the magnets through the helium piping. Therefore, the temperature and flow rate measurements shall be reliable and accurate. In this paper, we present the thermometric chains as well as the venturi flow meters installed in the ITER magnets and their helium piping. The presented thermometric block design is based on the design developed by CERN for the LHC, which has been further optimized via thermal simulations carried out by CEA. The electronic part of the thermometric chain was entirely developed by the CEA and will be presented in detail: it is based on a lock-in measurement and small signal amplification, and also provides a web interface and software to an industrial PLC. This measuring device provides a reliable, accurate, electromagnetically immune, and fast (up to 100 Hz bandwidth) system for resistive temperature sensors between a few ohms to 100 kΩ. The flowmeters (venturi type) which make up part of the helium mass flow measurement chain have been completely designed, and manufacturing is on-going. The behaviour of the helium gas has been studied in detailed thanks to ANSYS CFX software in order to obtain the same differential pressure for all types of flowmeters. Measurement uncertainties have been estimated and the influence of input parameters has been studied. Mechanical calculations have been performed to guarantee the mechanical strength of the venturis required for pressure equipment operating in nuclear environment. In order to complete the helium mass flow measurement chain, different technologies of absolute and differential pressure sensors have been tested in an applied magnetic field to identify equipment compatible with the ITER environment.

  14. Beryllium in the ITER blanket

    Energy Technology Data Exchange (ETDEWEB)

    Billone, M.C.

    1995-01-01

    This paper consists of viewgraphs used in a presentation on the application of beryllium in breeding blankets for ITER and JET. The paper brings together data on the physical, thermal, mechanical, and chemical properties of beryllium and beryllium oxide for this type of application, as well as issues of compatibility with construction materials, and irradiation experience. It includes the results from testing programs carried out to arrive at some of the information, including fabrication work, irradiation experiments, and sample tests performed both in and out of the irradiation piles.

  15. Development of core sampling technique for ITER Type B radwaste

    Energy Technology Data Exchange (ETDEWEB)

    Kim, S. G.; Hong, K. P.; Oh, W. H.; Park, M. C.; Jung, S. H.; Ahn, S. B. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    Type B radwaste (intermediate level and long lived radioactive waste) imported from ITER vacuum vessel are to be treated and stored in basement of hot cell building. The Type B radwaste treatment process is composed of buffer storage, cutting, sampling/tritium measurement, tritium removal, characterization, pre-packaging, inspection/decontamination, and storage etc. The cut slices of Type B radwaste components generated from cutting process undergo sampling process before and after tritium removal process. The purpose of sampling is to obtain small pieces of samples in order to investigate the tritium content and concentration of Type B radwaste. Core sampling, which is the candidates of sampling technique to be applied to ITER hot cell, is available for not thick (less than 50 mm) metal without use of coolant. Experimented materials were SS316L and CuCrZr in order to simulate ITER Type B radwaste. In core sampling, substantial secondary wastes from cutting chips will be produced unavoidably. Thus, core sampling machine will have to be equipped with disposal system such as suction equipment. Core sampling is considered an unfavorable method for tool wear compared to conventional drilling.

  16. Iterated upwind schemes for gas dynamics

    Science.gov (United States)

    Smolarkiewicz, Piotr K.; Szmelter, Joanna

    2009-01-01

    A class of high-resolution schemes established in integration of anelastic equations is extended to fully compressible flows, and documented for unsteady (and steady) problems through a span of Mach numbers from zero to supersonic. The schemes stem from iterated upwind technology of the multidimensional positive definite advection transport algorithm (MPDATA). The derived algorithms employ standard and modified forms of the equations of gas dynamics for conservation of mass, momentum and either total or internal energy as well as potential temperature. Numerical examples from elementary wave propagation, through computational aerodynamics benchmarks, to atmospheric small- and large-amplitude acoustics with intricate wave-flow interactions verify the approach for both structured and unstructured meshes, and demonstrate its flexibility and robustness.

  17. Novel Candidate Genes and a Wide Spectrum of Structural and Point Mutations Responsible for Inherited Retinal Dystrophies Revealed by Exome Sequencing

    Science.gov (United States)

    de Castro-Miró, Marta; Tonda, Raul; Escudero-Ferruz, Paula; Andrés, Rosa; Mayor-Lorenzo, Andrés; Castro, Joaquín; Ciccioli, Marcela; Hidalgo, Daniel A.; Rodríguez-Ezcurra, Juan José; Farrando, Jorge; Pérez-Santonja, Juan J.; Cormand, Bru; Marfany, Gemma

    2016-01-01

    Background NGS-based genetic diagnosis has completely revolutionized the human genetics field. In this study, we have aimed to identify new genes and mutations by Whole Exome Sequencing (WES) responsible for inherited retinal dystrophies (IRD). Methods A cohort of 33 pedigrees affected with a variety of retinal disorders was analysed by WES. Initial prioritization analysis included around 300 IRD-associated genes. In non-diagnosed families a search for pathogenic mutations in novel genes was undertaken. Results Genetic diagnosis was attained in 18 families. Moreover, a plausible candidate is proposed for 10 more cases. Two thirds of the mutations were novel, including 4 chromosomal rearrangements, which expand the IRD allelic heterogeneity and highlight the contribution of private mutations. Our results prompted clinical re-evaluation of some patients resulting in assignment to a syndromic instead of non-syndromic IRD. Notably, WES unveiled four new candidates for non-syndromic IRD: SEMA6B, CEP78, CEP250, SCLT1, the two latter previously associated to syndromic disorders. We provide functional data supporting that missense mutations in CEP250 alter cilia formation. Conclusion The diagnostic efficiency of WES, and strictly following the ACMG/AMP criteria is 55% in reported causative genes or functionally supported new candidates, plus 30% families in which likely pathogenic or VGUS/VUS variants were identified in plausible candidates. Our results highlight the clinical utility of WES for molecular diagnosis of IRD, provide a wider spectrum of mutations and concomitant genetic variants, and challenge our view on syndromic vs non-syndromic, and causative vs modifier genes. PMID:28005958

  18. Variability of candidate genes, genetic structure and association with sugar accumulation and climacteric behavior in a broad germplasm collection of melon (Cucumis melo L.)

    OpenAIRE

    2015-01-01

    [EN] Background A collection of 175 melon (Cucumis melo L.) accessions (including wild relatives, feral types, landraces, breeding lines and commercial cultivars) from 50 countries was selected to study the phenotypic variability for ripening behavior and sugar accumulation. The variability of single nucleotide polymorphisms (SNPs) at 53 selected candidate genes involved in sugar accumulation and fruit ripening processes was studied, as well as their association with p...

  19. Status of US ITER Diagnostics

    Science.gov (United States)

    Stratton, B.; Delgado-Aparicio, L.; Hill, K.; Johnson, D.; Pablant, N.; Barnsley, R.; Bertschinger, G.; de Bock, M. F. M.; Reichle, R.; Udintsev, V. S.; Watts, C.; Austin, M.; Phillips, P.; Beiersdorfer, P.; Biewer, T. M.; Hanson, G.; Klepper, C. C.; Carlstrom, T.; van Zeeland, M. A.; Brower, D.; Doyle, E.; Peebles, A.; Ellis, R.; Levinton, F.; Yuh, H.

    2013-10-01

    The US is providing 7 diagnostics to ITER: the Upper Visible/IR cameras, the Low Field Side Reflectometer, the Motional Stark Effect diagnostic, the Electron Cyclotron Emission diagnostic, the Toroidal Interferometer/Polarimeter, the Core Imaging X-Ray Spectrometer, and the Diagnostic Residual Gas Analyzer. The front-end components of these systems must operate with high reliability in conditions of long pulse operation, high neutron and gamma fluxes, very high neutron fluence, significant neutron heating (up to 7 MW/m3) , large radiant and charge exchange heat flux (0.35 MW/m2) , and high electromagnetic loads. Opportunities for repair and maintenance of these components will be limited. These conditions lead to significant challenges for the design of the diagnostics. Space constraints, provision of adequate radiation shielding, and development of repair and maintenance strategies are challenges for diagnostic integration into the port plugs that also affect diagnostic design. The current status of design of the US ITER diagnostics is presented and R&D needs are identified. Supported by DOE contracts DE-AC02-09CH11466 (PPPL) and DE-AC05-00OR22725 (UT-Battelle, LLC).

  20. ETR/ITER systems code

    Energy Technology Data Exchange (ETDEWEB)

    Barr, W.L.; Bathke, C.G.; Brooks, J.N.; Bulmer, R.H.; Busigin, A.; DuBois, P.F.; Fenstermacher, M.E.; Fink, J.; Finn, P.A.; Galambos, J.D.; Gohar, Y.; Gorker, G.E.; Haines, J.R.; Hassanein, A.M.; Hicks, D.R.; Ho, S.K.; Kalsi, S.S.; Kalyanam, K.M.; Kerns, J.A.; Lee, J.D.; Miller, J.R.; Miller, R.L.; Myall, J.O.; Peng, Y-K.M.; Perkins, L.J.; Spampinato, P.T.; Strickler, D.J.; Thomson, S.L.; Wagner, C.E.; Willms, R.S.; Reid, R.L. (ed.)

    1988-04-01

    A tokamak systems code capable of modeling experimental test reactors has been developed and is described in this document. The code, named TETRA (for Tokamak Engineering Test Reactor Analysis), consists of a series of modules, each describing a tokamak system or component, controlled by an optimizer/driver. This code development was a national effort in that the modules were contributed by members of the fusion community and integrated into a code by the Fusion Engineering Design Center. The code has been checked out on the Cray computers at the National Magnetic Fusion Energy Computing Center and has satisfactorily simulated the Tokamak Ignition/Burn Experimental Reactor II (TIBER) design. A feature of this code is the ability to perform optimization studies through the use of a numerical software package, which iterates prescribed variables to satisfy a set of prescribed equations or constraints. This code will be used to perform sensitivity studies for the proposed International Thermonuclear Experimental Reactor (ITER). 22 figs., 29 tabs.

  1. ITER Port Interspace Pressure Calculations

    Energy Technology Data Exchange (ETDEWEB)

    Carbajo, Juan J [ORNL; Van Hove, Walter A [ORNL

    2016-01-01

    The ITER Vacuum Vessel (VV) is equipped with 54 access ports. Each of these ports has an opening in the bioshield that communicates with a dedicated port cell. During Tokamak operation, the bioshield opening must be closed with a concrete plug to shield the radiation coming from the plasma. This port plug separates the port cell into a Port Interspace (between VV closure lid and Port Plug) on the inner side and the Port Cell on the outer side. This paper presents calculations of pressures and temperatures in the ITER (Ref. 1) Port Interspace after a double-ended guillotine break (DEGB) of a pipe of the Tokamak Cooling Water System (TCWS) with high temperature water. It is assumed that this DEGB occurs during the worst possible conditions, which are during water baking operation, with water at a temperature of 523 K (250 C) and at a pressure of 4.4 MPa. These conditions are more severe than during normal Tokamak operation, with the water at 398 K (125 C) and 2 MPa. Two computer codes are employed in these calculations: RELAP5-3D Version 4.2.1 (Ref. 2) to calculate the blowdown releases from the pipe break, and MELCOR, Version 1.8.6 (Ref. 3) to calculate the pressures and temperatures in the Port Interspace. A sensitivity study has been performed to optimize some flow areas.

  2. Iterated Stretching of Viscoelastic Jets

    Science.gov (United States)

    Chang, Hsueh-Chia; Demekhin, Evgeny A.; Kalaidin, Evgeny

    1999-01-01

    We examine, with asymptotic analysis and numerical simulation, the iterated stretching dynamics of FENE and Oldroyd-B jets of initial radius r(sub 0), shear viscosity nu, Weissenberg number We, retardation number S, and capillary number Ca. The usual Rayleigh instability stretches the local uniaxial extensional flow region near a minimum in jet radius into a primary filament of radius [Ca(1 - S)/ We](sup 1/2)r(sub 0) between two beads. The strain-rate within the filament remains constant while its radius (elastic stress) decreases (increases) exponentially in time with a long elastic relaxation time 3We(r(sup 2, sub 0)/nu). Instabilities convected from the bead relieve the tension at the necks during this slow elastic drainage and trigger a filament recoil. Secondary filaments then form at the necks from the resulting stretching. This iterated stretching is predicted to occur successively to generate high-generation filaments of radius r(sub n), (r(sub n)/r(sub 0)) = square root of 2[r(sub n-1)/r(sub 0)](sup 3/2) until finite-extensibility effects set in.

  3. Linearized Bregman Iteration Algorithm for Matrix Completion with Structural Noise%基于线性 Bregman 迭代的结构化噪声矩阵补全算法

    Institute of Scientific and Technical Information of China (English)

    陈蕾; 杨庚; 陈正宇; 肖甫; 陈松灿

    2015-01-01

    ,by introducing the L2 ,1-norm regularization method,which is a popular trick in classifier design field,we formulate the matrix completion problem with structural noise as a convex constrained optimization problem based L2 ,1-norm regu-larization.Then,in order to quickly and efficiently solve the convex constrained optimization problem,by generalizing the linearized Bregman iteration algorithm and the proximal operator method from vector space to the matrix space,we propose a robust linearized Bregman iteration algorithm called LiBIMC for matrix completion with structural noise.The theoretical analysis proves that the fixed point of the LiBIMC algorithm is exactly the global optimal solution of this matrix completion problem.Finally,numerical experiments show that,compared with other algorithms,the LiBIMC algorithm can better recover the matrix using correct measurements and detect the positions where the data is ruined.

  4. Influence of soil-structure interaction on system identification of building. Part 2. Iterative identification method using regression curves; Jiban kozobutsu sogo sayo ga kozobutsu no shindo tokusei suitei ni oyobosu eikyo. 2. Kaikishiki to hanpuku keisan ni yoru tokusei suiteiho no teian

    Energy Technology Data Exchange (ETDEWEB)

    Yamaya, H.; Naito, Y.; Ishibashi, T. [Kajima Corp., Tokyo (Japan)

    1995-12-20

    When the dynamic characteristics of structures are identified using data obtained from microtremors or earthquakes as well as from vibration tests with an exciter, the effect of soil-structure interaction on the data together with the effects of disturbances, such as wind force, makes it difficult to identify the characteristics of the structure and soil. A method was previously provided for identifying the characteristics of structure and soil-structure interaction respectively using two-particle systems composed of one particle for the super-structure and another for the base. In this paper, a method is proposed for determining two regression curves with two unknown parameters, i.e., a resonance frequency and a damping ratio, through numeric iteration. At first, parameters were extracted, for which regression curves seem relatively easy to obtain according to the previous discussion, and then, regression curves were calculated by numeric iteration to improve accuracy. Consequently, it was found that regression curves can be used to identify unknown parameters when two among four parameters, i.e., resonance frequencies and damping ratios of super-structure and interaction components, are obtained through experiments. 1 ref., 12 figs., 1 tab.

  5. Technical issues of RAFMs for the fabrication of ITER Test Blanket Module

    Energy Technology Data Exchange (ETDEWEB)

    Tanigawa, Hiroyasu; Hirose, Takanori; Shiba, Kiyoyuki [Japan Atomic Energy Agency (JP)] (and others)

    2007-07-01

    Reduced activation ferritic/martensitic steels (RAFMs) are recognized as the primary candidate structural materials for fusion blanket systems, as it has they have been developed based on massive industrial experience of ferritic/martensitic steel replacing Mo and Nb of high chromium heat resistant martensitic steels (such as modified 9Cr-1Mo) with W and Ta, respectively. F82H and JLF-1 are RAFMs, which have been developed and studied in Japan and the various effects of irradiation were reported. F82H is designed with emphasis on high temperature property and weldability, and was provided and evaluated in various countries as a part of the IEA fusion materials development collaboration. The JAEA/US collaboration program also has been conducted with the emphasis on irradiation effects of F82H. Now, among the existing database for RAFMs the most extensive one is that for F82H. The objective of this paper is to review the R and D status of F82H and to identify the key technical issues for the fabrication of ITER Test Blanket Module (TBM) suggested from the recent achievements in Japan. It is desirable to make the status of RAFMs equivalent to commercial steels to use RAFMs as the ITER-TBM structural material. This would require demonstrating the reproducibility and weldability as well as providing the database. The excellent reproducibility of F82H has been demonstrated with four 5-ton-heats, and two of them were provided as F82H-IEA heats. It has been also proved that F82H could be provided as plates (thickness of 1.5 to 55 mm), pipes and rectangular tubes. It is also important to have the excellent weldability as the TBM has about 300m length of weld line, and it was proved through TIG, EB and YAG weld test performed in air atmosphere. Various mechanical and microstructural data have been accumulated including long-term tests such as creep rupture tests and aging tests. Although F82H is a well-perceived RAFM as the ITER-TBM structural material, some issues are

  6. A new iterative triclass thresholding technique in image segmentation.

    Science.gov (United States)

    Cai, Hongmin; Yang, Zhong; Cao, Xinhua; Xia, Weiming; Xu, Xiaoyin

    2014-03-01

    We present a new method in image segmentation that is based on Otsu's method but iteratively searches for subregions of the image for segmentation, instead of treating the full image as a whole region for processing. The iterative method starts with Otsu's threshold and computes the mean values of the two classes as separated by the threshold. Based on the Otsu's threshold and the two mean values, the method separates the image into three classes instead of two as the standard Otsu's method does. The first two classes are determined as the foreground and background and they will not be processed further. The third class is denoted as a to-be-determined (TBD) region that is processed at next iteration. At the succeeding iteration, Otsu's method is applied on the TBD region to calculate a new threshold and two class means and the TBD region is again separated into three classes, namely, foreground, background, and a new TBD region, which by definition is smaller than the previous TBD regions. Then, the new TBD region is processed in the similar manner. The process stops when the Otsu's thresholds calculated between two iterations is less than a preset threshold. Then, all the intermediate foreground and background regions are, respectively, combined to create the final segmentation result. Tests on synthetic and real images showed that the new iterative method can achieve better performance than the standard Otsu's method in many challenging cases, such as identifying weak objects and revealing fine structures of complex objects while the added computational cost is minimal.

  7. Adaptive beam-forming algorithm with iterative subspace tracking and structural constraint%迭代子空间跟踪和结构约束的自适应波束形成算法

    Institute of Scientific and Technical Information of China (English)

    贺顺; 杨志伟; 廖桂生

    2012-01-01

    The maximum output signal to interference plus noise ration (SINR) can be achieved as weighted the array data ' s by adopting adaptive beam-forming (ABF) algorithm. Therefore, the deviation between the estimated sample matrix and the ideally correlation matrix will deteriorate the performance of the linearly constrained minimum variance (LCMV) beam-former. To alleviate this decreasing in output SINR with secondary data deficient scenario and channel mismatch coexistence, a new method based on iterative subspace tracking and structural constraint is presented. The approach is perr formed in two stages. First, we employ clearing operation at training data set to calculate each principal eigenvector in sequentially, then, the adaptive beam-forming algorithm based on subspace projection can be obtained by constraining its weight vector to a specific form. The high output signal to interference plus noise ration of subspace processing is remained and the robustness against small sample support and in the presence of channel mismatch is improved. Numerical simulation indicate that its performance is better than that of several well-known adaptive beam-former.%自适应波束形成(adaptive beam-forming:ABF)方法通过对阵列数据进行加权处理来获得最大的输出信干噪比,对采样协方差矩阵依赖性较大.在小快拍和通道随机响应误差条件下,采样协方差矩阵的估计值与真实值通常存在较大差异,严重恶化了基于线性约束最小均方误差准则的自适应波束形成方法的干扰抑制性能.针对该问题,本文基于子空间投影类波束形成方法的思想,提出采用迭代子空间跟踪和结构约束的自适应波束形成方法.该方法首先利用clearing技术在训练样本集上依次跟踪主特征矢量并构成信号子空间;然后根据子空间投影类波束形成权矢量的结构特性计算自适应加权矢量.仿真结果表明本文方法能有效提高自适应波束算法的输出信干噪比.

  8. A FAST CONVERGENT METHOD OF ITERATED REGULARIZATION

    Institute of Scientific and Technical Information of China (English)

    Huang Xiaowei; Wu Chuansheng; Wu Di

    2009-01-01

    This article presents a fast convergent method of iterated regularization based on the idea of Landweber iterated regularization, and a method for a-posteriori choice by the Morozov discrepancy principle and the optimum asymptotic convergence order of the regularized solution is obtained. Numerical test shows that the method of iterated regu-larization can quicken the convergence speed and reduce the calculation burden efficiently.

  9. Preconditioned iterations to calculate extreme eigenvalues

    Energy Technology Data Exchange (ETDEWEB)

    Brand, C.W.; Petrova, S. [Institut fuer Angewandte Mathematik, Leoben (Austria)

    1994-12-31

    Common iterative algorithms to calculate a few extreme eigenvalues of a large, sparse matrix are Lanczos methods or power iterations. They converge at a rate proportional to the separation of the extreme eigenvalues from the rest of the spectrum. Appropriate preconditioning improves the separation of the eigenvalues. Davidson`s method and its generalizations exploit this fact. The authors examine a preconditioned iteration that resembles a truncated version of Davidson`s method with a different preconditioning strategy.

  10. Research at ITER towards DEMO: Specific reactor diagnostic studies to be carried out on ITER

    Energy Technology Data Exchange (ETDEWEB)

    Krasilnikov, A. V.; Kaschuck, Y. A.; Vershkov, V. A.; Petrov, A. A.; Petrov, V. G.; Tugarinov, S. N. [Institution Project center ITER, Moscow (Russian Federation)

    2014-08-21

    In ITER diagnostics will operate in the very hard radiation environment of fusion reactor. Extensive technology studies are carried out during development of the ITER diagnostics and procedures of their calibration and remote handling. Results of these studies and practical application of the developed diagnostics on ITER will provide the direct input to DEMO diagnostic development. The list of DEMO measurement requirements and diagnostics will be determined during ITER experiments on the bases of ITER plasma physics results and success of particular diagnostic application in reactor-like ITER plasma. Majority of ITER diagnostic already passed the conceptual design phase and represent the state of the art in fusion plasma diagnostic development. The number of related to DEMO results of ITER diagnostic studies such as design and prototype manufacture of: neutron and γ–ray diagnostics, neutral particle analyzers, optical spectroscopy including first mirror protection and cleaning technics, reflectometry, refractometry, tritium retention measurements etc. are discussed.

  11. Research at ITER towards DEMO: Specific reactor diagnostic studies to be carried out on ITER

    Science.gov (United States)

    Krasilnikov, A. V.; Kaschuck, Y. A.; Vershkov, V. A.; Petrov, A. A.; Petrov, V. G.; Tugarinov, S. N.

    2014-08-01

    In ITER diagnostics will operate in the very hard radiation environment of fusion reactor. Extensive technology studies are carried out during development of the ITER diagnostics and procedures of their calibration and remote handling. Results of these studies and practical application of the developed diagnostics on ITER will provide the direct input to DEMO diagnostic development. The list of DEMO measurement requirements and diagnostics will be determined during ITER experiments on the bases of ITER plasma physics results and success of particular diagnostic application in reactor-like ITER plasma. Majority of ITER diagnostic already passed the conceptual design phase and represent the state of the art in fusion plasma diagnostic development. The number of related to DEMO results of ITER diagnostic studies such as design and prototype manufacture of: neutron and γ-ray diagnostics, neutral particle analyzers, optical spectroscopy including first mirror protection and cleaning technics, reflectometry, refractometry, tritium retention measurements etc. are discussed.

  12. Reflective metallic coatings for first mirrors on ITER

    Energy Technology Data Exchange (ETDEWEB)

    Eren, Baran, E-mail: baran.eren@unibas.ch [Department of Physics, University of Basel, Klingelbergstrasse 82, CH-4056 Basel (Switzerland); Marot, Laurent [Department of Physics, University of Basel, Klingelbergstrasse 82, CH-4056 Basel (Switzerland); Litnovsky, Andrey; Matveeva, Maria [Institut fuer Energieforschung (Plasmaphysik), Forschungszentrum Juelich, Association EURATOM-FZJ, D 52425 Juelich (Germany); Steiner, Roland; Emberger, Valentin; Wisse, Marco [Department of Physics, University of Basel, Klingelbergstrasse 82, CH-4056 Basel (Switzerland); Mathys, Daniel [Centre of Microscopy, University of Basel, Klingelbergstrasse 50/70, CH-4056 Basel (Switzerland); Covarel, Gregory [Laboratoire de Physique et Mecanique Textile EA CNRS 7189, Universite de Haute Alsace, 61 rue Albert Camus, 68093 Mulhouse Cedex (France); Meyer, Ernst [Department of Physics, University of Basel, Klingelbergstrasse 82, CH-4056 Basel (Switzerland)

    2011-10-15

    Metallic mirrors are foreseen to play a crucial role for all optical diagnostics in ITER. Therefore, the development of reliable techniques for the production of mirrors which are able to maintain their optical properties in the harsh ITER environment is highly important. By applying magnetron sputtering and evaporation techniques, rhodium and molybdenum films have been prepared for tokamak tests. The films were characterised in terms of chemical composition, surface roughness, crystallite structure, reflectivity and adhesion. No impurities were detected on the surface after deposition. The effects of deposition parameters and substrate temperature on the resulting crystallite structure, surface roughness and hence on the reflectivity, were investigated. The films are found to exhibit nanometric crystallites with a dense columnar structure. Open boundaries between the crystallite columns, which are sometimes present after evaporation, are found to reduce the reflectivity as compared to rhodium or molybdenum references.

  13. Benchmarking ICRF simulations for ITER

    Energy Technology Data Exchange (ETDEWEB)

    R. V. Budny, L. Berry, R. Bilato, P. Bonoli, M. Brambilla, R.J. Dumont, A. Fukuyama, R. Harvey, E.F. Jaeger, E. Lerche, C.K. Phillips, V. Vdovin, J. Wright, and members of the ITPA-IOS

    2010-09-28

    Abstract Benchmarking of full-wave solvers for ICRF simulations is performed using plasma profiles and equilibria obtained from integrated self-consistent modeling predictions of four ITER plasmas. One is for a high performance baseline (5.3 T, 15 MA) DT H-mode plasma. The others are for half-field, half-current plasmas of interest for the pre-activation phase with bulk plasma ion species being either hydrogen or He4. The predicted profiles are used by seven groups to predict the ICRF electromagnetic fields and heating profiles. Approximate agreement is achieved for the predicted heating power partitions for the DT and He4 cases. Profiles of the heating powers and electromagnetic fields are compared.

  14. Truncated states obtained by iteration

    CERN Document Server

    Cardoso, W B

    2007-01-01

    Quantum states of the electromagnetic field are of considerable importance, finding potential application in various areas of physics, as diverse as solid state physics, quantum communication and cosmology. In this paper we introduce the concept of truncated states obtained via iterative processes (TSI) and study its statistical features, making an analogy with dynamical systems theory (DST). As a specific example, we have studied TSI for the doubling and the logistic functions, which are standard functions in studying chaos. TSI for both the doubling and logistic functions exhibit certain similar patterns when their statistical features are compared from the point of view of DST. A general method to engineer TSI in the running-wave domain is employed, which includes the errors due to the nonidealities of detectors and photocounts.

  15. Planning as an Iterative Process

    Science.gov (United States)

    Smith, David E.

    2012-01-01

    Activity planning for missions such as the Mars Exploration Rover mission presents many technical challenges, including oversubscription, consideration of time, concurrency, resources, preferences, and uncertainty. These challenges have all been addressed by the research community to varying degrees, but significant technical hurdles still remain. In addition, the integration of these capabilities into a single planning engine remains largely unaddressed. However, I argue that there is a deeper set of issues that needs to be considered namely the integration of planning into an iterative process that begins before the goals, objectives, and preferences are fully defined. This introduces a number of technical challenges for planning, including the ability to more naturally specify and utilize constraints on the planning process, the ability to generate multiple qualitatively different plans, and the ability to provide deep explanation of plans.

  16. Aggregation-iterative analogues and generalizations of projection-iterative methods

    Directory of Open Access Journals (Sweden)

    Shuvar B.F.

    2013-06-01

    Full Text Available Aggregation-iterative algorithms for linear operator equations are constructed and investigated. These algorithms cover methods of iterative aggregation and projection-iterative methods. In convergence conditions there is neither requirement for the corresponding operator of fixed sign no restriction to the spectral radius to be less than one.

  17. Installation of the ITER committee industry. Participants guide; Installation du Comite industrie ITER. Dossier des participants

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    ITER is an international project to design and build an experimental fusion reactor based on the tokamak concept. This guide presents the ITER project and objectives and the associated organizations in France, the recommendations and actions for ITER, the industrial mobilization, the industrial committee and its members, technological sheets for the enterprises and the statistical document of the SESSI. (A.L.B.)

  18. Rater Variables Associated with ITER Ratings

    Science.gov (United States)

    Paget, Michael; Wu, Caren; McIlwrick, Joann; Woloschuk, Wayne; Wright, Bruce; McLaughlin, Kevin

    2013-01-01

    Advocates of holistic assessment consider the ITER a more authentic way to assess performance. But this assessment format is subjective and, therefore, susceptible to rater bias. Here our objective was to study the association between rater variables and ITER ratings. In this observational study our participants were clerks at the University of…

  19. Dense Iterative Contextual Pixel Classification using Kriging

    DEFF Research Database (Denmark)

    Ganz, Melanie; Loog, Marco; Brandt, Sami

    2009-01-01

    have been proposed to this end, e.g., iterative contextual pixel classification, iterated conditional modes, and other approaches related to Markov random fields. A problem of these methods, however, is their computational complexity, especially when dealing with high-resolution images in which...

  20. Iterative Brinkman penalization for remeshed vortex methods

    DEFF Research Database (Denmark)

    Hejlesen, Mads Mølholm; Koumoutsakos, Petros; Leonard, Anthony;

    2015-01-01

    We introduce an iterative Brinkman penalization method for the enforcement of the no-slip boundary condition in remeshed vortex methods. In the proposed method, the Brinkman penalization is applied iteratively only in the neighborhood of the body. This allows for using significantly larger time s...

  1. ITER Fast Ion Collective Thomson Scattering

    DEFF Research Database (Denmark)

    Bindslev, Henrik; Meo, Fernando; Korsholm, Søren Bang

    for measurements of the confined fusion alpha particles in ITER set by the ITER team. Then we outline the considerations, which enter into the selection and evaluation of CTS systems. System definition includes choice of probe frequency, geometry of probe and receiver beam patterns and probe power, but ultimately...

  2. An iterative method for spherical bounces

    CERN Document Server

    Buniy, Roman V

    2016-01-01

    We develop a new iterative method for finding approximate solutions for spherical bounces associated with the decay of the false vacuum in scalar field theories. The method works for any generic potential in any number of dimensions, contains Coleman's thin-wall approximation as its first iteration, and greatly improves its accuracy by including higher order terms.

  3. Iterative methods for weighted least-squares

    Energy Technology Data Exchange (ETDEWEB)

    Bobrovnikova, E.Y.; Vavasis, S.A. [Cornell Univ., Ithaca, NY (United States)

    1996-12-31

    A weighted least-squares problem with a very ill-conditioned weight matrix arises in many applications. Because of round-off errors, the standard conjugate gradient method for solving this system does not give the correct answer even after n iterations. In this paper we propose an iterative algorithm based on a new type of reorthogonalization that converges to the solution.

  4. Experimental studies of ITER demonstration discharges

    NARCIS (Netherlands)

    Sips, A.C.C.; Casper, T. A.; Doyle, E. J.; Giruzzi, G.; Gribov, Y.; Hobirk, J.; Hogeweij, G. M. D.; Horton, L. D.; Hubbard, A. E.; Hutchinson, I.; Ide, S.; Isayama, A.; Imbeaux, F.; Jackson, G. L.; Kamada, Y.; Kessel, C.; Kochl, F.; Lomas, P.; Litaudon, X.; Luce, T. C.; Marmar, E.; Mattei, M.; Nunes, I.; Oyama, N.; Parail, V.; Portone, A.; Saibene, G.; Sartori, R.; Stober, J. K.; Suzuki, T.; Wolfe, S. M.

    2009-01-01

    Key parts of the ITER scenarios are determined by the capability of the proposed poloidal field (PF) coil set. They include the plasma breakdown at low loop voltage, the current rise phase, the performance during the flat top (FT) phase and a ramp down of the plasma. The ITER discharge evolution has

  5. Preparation to manufacturing of ITER plasma facing components in Russia

    Energy Technology Data Exchange (ETDEWEB)

    Mazul, I.V., E-mail: mazuliv@niiefa.spb.su [Efremov Institute, St. Petersburg, 196641 (Russian Federation); Belyakov, V.A.; Giniatulin, R.N.; Gervash, A.A.; Kuznetsov, V.E.; Makhankov, A.N. [Efremov Institute, St. Petersburg, 196641 (Russian Federation); Sizenev, V.S. [Corporation ' Kompozit' , Korolev, 141070 (Russian Federation)

    2011-10-15

    The preparation of the procurement activities for the ITER plasma-facing-components (PFC) is currently well underway. Three ITER procurement packages associated with PFCs are currently allocated to the Russian Federation (RF): delivery of the central assembly of the divertor (dome and reflector plates assemblies), delivery of 40% of the first-wall (FW) panels and high heat flux testing of divertor components during the qualification and subsequent manufacturing phases. The results of the qualification process for these tasks undertaken by RF industry are presented. Qualification mockups of the dome divertor structure were successfully manufactured in accordance with the ITER specifications and tested at heat fluxes exceeding operational ones. The maturity and reliability of the proposed design and manufacturing technologies, proposed by RF industry, was therefore demonstrated. To confirm the manufacturing readiness of technologies proposed for the fabrication of the ITER first wall, three qualification mockups were fabricated. Two were heat flux tested in two facilities abroad. In addition to launching the qualification process, the PFC team at Efremov Institute is preparing the industrial facilities for serial production of above mentioned components. A brief description of such facilities is presented in this paper, together with the manufacturing technologies to be used. Two electron beam facilities (Tsefey and IDTF) for various high heat flux testing of PFC components are also described.

  6. Landweber iterative regularization for nearfield acoustic holography

    Institute of Scientific and Technical Information of China (English)

    BI Chuanxing; CHEN Xinzhao; ZHOU Rong; CHEN Jian

    2006-01-01

    On the basis of the distributed source boundary point method (DSBPM)-based nearfield acoustic holography (NAH), Landweber iterative regularization method is proposed to stabilize the NAH reconstruction process, control the influence of measurement errors on the reconstructed results and ensure the validity of the reconstructed results. And a new method, the auxiliary surface method, is proposed to determine the optimal iterative number for optimizing the regularization effect. Here, the optimal number is determined by minimizing the relative error between the calculated pressure on the auxiliary surface corresponding to each iterative number and the measured pressure. An experiment on a speaker is investigated to demonstrate the high sensitivity of the reconstructed results to measurement errors and to validate the chosen method of the optimal iterative number and the Landweber iterative regularization method for controlling the influence of measurement errors on the reconstructed results.

  7. Seismic analysis of ITER fourth PF (Poloidal Field Coil) feeder

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Sumei, E-mail: smliu@ipp.ac.cn [School of Engineering, Anhui Agricultural University, Hefei 230036 (China); Institute of Plasma Physics, Chinese Academy of Science, Hefei 230031 (China); Chen, Wei [School of Engineering, Anhui Agricultural University, Hefei 230036 (China); Song, Yuntao; Ni, Xiaojun; Wang, Zhongwei [Institute of Plasma Physics, Chinese Academy of Science, Hefei 230031 (China); Chen, Yonghua; Gong, Chenyu [Magnet Division, TKM, ITER Organization, Route de Vinon sur Verdon, 13115 St. Paul Lez Durance (France)

    2014-10-15

    The ITER feeder systems connect the ITER magnet systems located inside the main cryostat to the cryo-plant, power-supply and control system interfaces outside the cryostat. The main purpose of the feeders is to convey the cryogenic supply and electrical power to the coils as well as house the instrumentation wiring. The PF busbar which carries 52 kA current will suffer from high Lorentz force due to the background magnetic field inspired by the coils and the self-field between every pair of busbars. Except their mechanical strength and thermal insulation performance must be achieved, the dynamic mechanism on PF structure should be assessed. This paper presents the simulation and seismic analysis on ITER 4th PF feeder including the Coil Terminal Box and S-bend Box (CTB and SBB), the Cryostat Feed-through (CFT), the In-Cryostat-Feeder (ICF), especially for the ground supports and main outer-tube firstly. This analysis aims to study seismic resistance on system design under local seismograms with floor response spectrum, the structural response vibration mode and response duration results of displacement, membrane stress, and bending stress on structure under different directions actuating signals were obtained by using the single-seismic spectrum analysis and Dead Weight analysis respectively. Based on the simulative and analytical results, the system seismic resistance and the integrity of the support structure in the 4th PF feeder have been studied and the detail design confirmed.

  8. AFLP genome scan to detect genetic structure and candidate loci under selection for local adaptation of the invasive weed Mikania micrantha.

    Directory of Open Access Journals (Sweden)

    Ting Wang

    Full Text Available Why some species become successful invaders is an important issue in invasive biology. However, limited genomic resources make it very difficult for identifying candidate genes involved in invasiveness. Mikania micrantha H.B.K. (Asteraceae, one of the world's most invasive weeds, has adapted rapidly in response to novel environments since its introduction to southern China. In its genome, we expect to find outlier loci under selection for local adaptation, critical to dissecting the molecular mechanisms of invasiveness. An explorative amplified fragment length polymorphism (AFLP genome scan was used to detect candidate loci under selection in 28 M. micrantha populations across its entire introduced range in southern China. We also estimated population genetic parameters, bottleneck signatures, and linkage disequilibrium. In binary characters, such as presence or absence of AFLP bands, if all four character combinations are present, it is referred to as a character incompatibility. Since character incompatibility is deemed to be rare in populations with extensive asexual reproduction, a character incompatibility analysis was also performed in order to infer the predominant mating system in the introduced M. micrantha populations. Out of 483 AFLP loci examined using stringent significance criteria, 14 highly credible outlier loci were identified by Dfdist and Bayescan. Moreover, remarkable genetic variation, multiple introductions, substantial bottlenecks and character compatibility were found to occur in M. micrantha. Thus local adaptation at the genome level indeed exists in M. micrantha, and may represent a major evolutionary mechanism of successful invasion. Interactions between genetic diversity, multiple introductions, and reproductive modes contribute to increase the capacity of adaptive evolution.

  9. Primary and Presidential Candidates

    DEFF Research Database (Denmark)

    Goddard, Joseph

    2012-01-01

    This article looks at primary and presidential candidates in 2008 and 2012. Evidence suggests that voters are less influenced by candidates’ color, gender, or religious observation than previously. Conversely, markers of difference remain salient in the imaginations of pollsters and journalists...

  10. An iterative approach to region growing using associative memories

    Science.gov (United States)

    Snyder, W. E.; Cowart, A.

    1983-01-01

    Region growing, often given as a classical example of the recursive control structures used in image processing which are often awkward to implement in hardware where the intent is the segmentation of an image at raster scan rates, is addressed in light of the postulate that any computation which can be performed recursively can be performed easily and efficiently by iteration coupled with association. Attention is given to an algorithm and hardware structure able to perform region labeling iteratively at scan rates. Every pixel is individually labeled with an identifier which signifies the region to which it belongs. Difficulties otherwise requiring recursion are handled by maintaining an equivalence table in hardware transparent to the computer, which reads the labeled pixels. A simulation of the associative memory has demonstrated its effectiveness.

  11. Active beam spectroscopy for ITER

    Energy Technology Data Exchange (ETDEWEB)

    Von Hellermann, M.; Giroud, C.; Jaspers, R. [Association Euratom-Fom, FOM Institute for Plasma Physics Rijnhuizen, Trilateral Euregio Cluster (Netherlands); Hawkes, N.C.; Mullane, M.O.; Zastrow, K.D. [Euratom/UKAEA Fusion Association, Culham Science Centre, Abingdon (United Kingdom); Krasilnikov, A.; Tugarinov, S. [SRC RF TRINITI, Troitsk, Moscow region (Russian Federation); Lotte, P. [Association Euratom-CEA Cadarache, 13 - Saint-Paul-lez-Durance (France). Dept. de Recherches sur la Fusion Controlee; McKee, G. [Wisconsin Univ., Madison, WI (United States); Malaquias, A. [Associacao EURATOM/IST, Instituto Superior Tecnico, Lisboa (Portugal); Rachlew, E. [Kungliga Tekniska Hoegskolan (KTH), Stockholm(Sweden)

    2003-07-01

    The latest status of 'Active Beam' related spectroscopy aspects as part of the ITER diagnostic scenario is presented. A key issue of the proposed scheme is based on the concept that in order to achieve the ultimate goal of global data consistency, all particles involved, that is, intrinsic and seeded impurity ions as well as helium ash ions and bulk plasma ions and also the plasma background data (e.g. magnetic and electric fields, electron density and temperature profiles) need to be addressed. A further sensible step in this direction is the decision of exploiting both a dedicated low-energy, low-power diagnostic beam (DNB, 2.2 MW 100 keV/amu) as well as the high-power, high-energy heating beams (HNB, 17 MW 500 keV/amu) for maximum diagnostic information. The authors report some new aspects referring to the use of DNB for motional Stark effect (MSE) where the main idea is to treat both beams (HNB and DNB) as potential diagnostic tools with complementary roles. The equatorial ports for the DNB promise excellent spatial resolution, however, the angles are less favourable for a polarimetric MSE exploitation. HNB can be used as probe beam for diagnosing slowing-down fusion alpha with a birth energy of 3,5 MeV.

  12. On the interplay between inner and outer iterations for a class of iterative methods

    Energy Technology Data Exchange (ETDEWEB)

    Giladi, E. [Stanford Univ., CA (United States)

    1994-12-31

    Iterative algorithms for solving linear systems of equations often involve the solution of a subproblem at each step. This subproblem is usually another linear system of equations. For example, a preconditioned iteration involves the solution of a preconditioner at each step. In this paper, the author considers algorithms for which the subproblem is also solved iteratively. The subproblem is then said to be solved by {open_quotes}inner iterations{close_quotes} while the term {open_quotes}outer iteration{close_quotes} refers to a step of the basic algorithm. The cost of performing an outer iteration is dominated by the solution of the subproblem, and can be measured by the number of inner iterations. A good measure of the total amount of work needed to solve the original problem to some accuracy c is then, the total number of inner iterations. To lower the amount of work, one can consider solving the subproblems {open_quotes}inexactly{close_quotes} i.e. not to full accuracy. Although this diminishes the cost of solving each subproblem, it usually slows down the convergence of the outer iteration. It is therefore interesting to study the effect of solving each subproblem inexactly on the total amount of work. Specifically, the author considers strategies in which the accuracy to which the inner problem is solved, changes from one outer iteration to the other. The author seeks the `optimal strategy`, that is, the one that yields the lowest possible cost. Here, the author develops a methodology to find the optimal strategy, from the set of slowly varying strategies, for some iterative algorithms. This methodology is applied to the Chebychev iteration and it is shown that for Chebychev iteration, a strategy in which the inner-tolerance remains constant is optimal. The author also estimates this optimal constant. Then generalizations to other iterative procedures are discussed.

  13. Design study of ITER-like divertor target for DEMO

    Energy Technology Data Exchange (ETDEWEB)

    Crescenzi, Fabio, E-mail: fabio.crescenzi@enea.it [ENEA, Unità Tecnica Fusione, ENEA C. R. Frascati, via E. Fermi 45, 00044 Frascati (Roma) (Italy); Bachmann, C. [EFDA, Power Plant Physics and Technology, Boltzmannstraße 2, 85748 Garching (Germany); Richou, M. [CEA, IRFM, F-13108 Saint Paul Lez Durance (France); Roccella, S.; Visca, E. [ENEA, Unità Tecnica Fusione, ENEA C. R. Frascati, via E. Fermi 45, 00044 Frascati (Roma) (Italy); You, J.-H. [Max-Planck-Institut für Plasmaphysik, Boltzmannstr. 2, 85748 Garching (Germany)

    2015-10-15

    Highlights: • ‘DEMO’ is a near-term Power Plant Conceptual Study (PPCS). • The ITER-like design concept represents a promising solution also for DEMO plasma facing units. • The optimization of PFUs aims to enhance the thermo-mechanical behaviour of the component. • The optimized geometry was evaluated by ITER SDC-IC criteria and in terms of low cycle fatigue (LCF). - Abstract: A near-term water-cooled target solution has to be evaluated together with the required technologies and its power exhaust limit under ‘DEMO’ conditions. The ITER-like design concept based on the mono-block technology using W as armour material and the CuCrZr-IG as structural material with an interlayer of pure copper represents a promising solution also for DEMO. This work reports the design study of an “optimized” ITER-like Water Cooled Divertor able to withstand a heat flux of 10 MW m{sup −2}, as requested for DEMO operating conditions. The optimization of plasma facing unit (PFU) aims to enhance the thermo-mechanical behaviour of the component by varying some geometrical parameters (monoblock size, interlayer thickness and, tube diameter and thickness). The optimization was performed by means of the multi-variable optimization algorithms using the FEM code ANSYS. The coolant hydraulic conditions (inlet pressure, temperature and velocity) were fixed for simplicity. This study is based on elastic analysis and 3 dimensional modelling. The resulting optimized geometry was evaluated on the basis of the ITER SDC-IC criteria and in terms of low cycle fatigue (LCF). The margin to the critical heat flux (CHF) was also estimated. Further design study (taking into account the effect of neutron radiation on the material properties) together with mock-up fabrication and high-heat-flux (HHF) tests are foreseen in next work programmes.

  14. ITER breeding blanket module design and analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kuroda, Toshimasa; Enoeda, Mikio; Kikuchi, Shigeto [Japan Atomic Energy Research Inst., Naka, Ibaraki (Japan). Naka Fusion Research Establishment] [and others

    1998-11-01

    The ITER breeding blanket employs a ceramic breeder and Be neutron multiplier both in small spherical pebble form. Radial-poloidal cooling panels are arranged in the blanket box to remove the nuclear heating in these materials and to reinforce the blanket structure. At the first wall, Be armor is bonded onto the stainless steel (SS) structure to provide a low Z plasma-compatible surface and to protect the first wall/blanket structure from the direct contact with the plasma during off-normal events. Thermo-mechanical analyses and investigation of fabrication procedure have been performed for this breeding blanket. To evaluate thermo-mechanical behavior of the pebble beds including the dependency of the effective thermal conductivity on stress, analysis methods have been preliminary established by the use of special calculation option of ABAQUS code, which are briefly summarized in this report. The structural response of the breeding blanket module under internal pressure of 4 MPa (in case of in-blanket LOCA) resulted in rather high stress in the blanket side (toroidal end) wall, thus addition of a stiffening rib or increase of the wall thickness will be needed. Two-dimensional elasto-plastic analyses have been performed for the Be/SS bonded interface at the first wall taking a fabrication process based on HIP bonding and thermal cycle due to pulsed plasma operation into account. The stress-strain hysteresis during these process and operation was clarified, and a procedure to assess and/or confirm the bonding integrity was also proposed. Fabrication sequence of the breeding blanket module was preliminarily developed based on the procedure to fabricate part by part and to assemble them one by one. (author)

  15. Newton—Like Iteration Method for Solving Algebraic Equations

    Institute of Scientific and Technical Information of China (English)

    JihuanHE

    1998-01-01

    In this paper,a Newton-like iteration method is proposed to solve an approximate solution of an algebraic equation.The iteration formula obtained by homotopy perturbation method contains the well-known Newton iteration formulain logic.

  16. Halpern Iteration in CAT(κ) Spaces

    Institute of Scientific and Technical Information of China (English)

    Bo(z)ena PI(A)TEK

    2011-01-01

    In this paper we show that an iterative sequence generated by the Halpern algorithm converges to a fixed point in the case of complete CAT(κ) spaces. Similar results for Hadamard manifolds were obtained in[Li,C.,López, G., Martín-Márquez, V.:Iterative algorithms for nonexpansive mappings on Hadamard manifolds. Taiwanese J. Math., 14, 541-559 (2010)], but we study a much more general case. Moreover, we discuss the Halpern iteration procedure for set-valued mappings.

  17. Iterative restoration algorithms for nonlinear constraint computing

    Science.gov (United States)

    Szu, Harold

    A general iterative-restoration principle is introduced to facilitate the implementation of nonlinear optical processors. The von Neumann convergence theorem is generalized to include nonorthogonal subspaces which can be reduced to a special orthogonal projection operator by applying an orthogonality condition. This principle is shown to permit derivation of the Jacobi algorithm, the recursive principle, the van Cittert (1931) deconvolution method, the iteration schemes of Gerchberg (1974) and Papoulis (1975), and iteration schemes using two Fourier conjugate domains (e.g., Fienup, 1981). Applications to restoring the image of a double star and division by hard and soft zeros are discussed, and sample results are presented graphically.

  18. Frozen Landweber Iteration for Nonlinear Ill-Posed Problems

    Institute of Scientific and Technical Information of China (English)

    J.Xu; B.Han; L.Li

    2007-01-01

    In this paper we propose a modification of the Landweber iteration termed frozen Landweber iteration for nonlinear ill-posed problems.A convergence analysis for this iteration is presented.The numerical performance of this frozen Landweber iteration for a nonlinear Hammerstein integral equation is compared with that of the Landweber iteration.We obtain a shorter running time of the frozen Landweber iteration based on the same convergence accuracy.

  19. Recovery of the Candidate Protoplanet HD 100546 b with Gemini/NICI and Detection of Additional (Planet-Induced?) Disk Structure at Small Separations

    CERN Document Server

    Currie, Thayne; Kudo, Tomoyuki; Honda, Mitsuhiko; Brandt, Timothy D; Grady, Carol; Fukagawa, Misato; Burrows, Adam; Janson, Markus; Kuzuhara, Masayuki; McElwain, Michael W; Follette, Katherine; Hashimoto, Jun; Henning, Thomas; Kandori, Ryo; Kusakabe, Nobuhiko; Kwon, Jungmi; Mede, Kyle; Morino, Jun-ichi; Nishikawa, Jun; Pyo, Tae-Soo; Serabyn, Gene; Suenaga, Takuya; Takahashi, Yasuhiro; Wisniewski, John; Tamura, Motohide

    2014-01-01

    We report the first independent, second-epoch (re-)detection of a directly-imaged protoplanet candidate. Using $L^\\prime$ high-contrast imaging of HD 100546 taken with the Near-Infrared Coronagraph and Imager (NICI) on Gemini South, we recover `HD 100546 b' with a position and brightness consistent with the original VLT/NaCo detection from Quanz et al, although data obtained after 2013 will be required to decisively demonstrate common proper motion. HD 100546 b may be spatially resolved, up to $\\approx$ 12-13 AU in diameter, and is embedded in a finger of thermal IR bright, polarized emission extending inwards to at least 0.3". Standard hot-start models imply a mass of $\\approx$ 15 $M_{J}$. But if HD 100546 b is newly formed or made visible by a circumplanetary disk, both of which are plausible, its mass is significantly lower (e.g. 1--7 $M_{J}$). Additionally, we discover a thermal IR-bright disk feature, possibly a spiral density wave, at roughly the same angular separation as HD 100546 b but 90 degrees awa...

  20. Pilot Candidate Selection

    Science.gov (United States)

    1989-05-01

    pilot selection system and to best support up-front track selection for SUPT? Assumptions The USAF Trainer Masterplan does not include a plan to...replace the T-41 with a new flight screening aircraft. In addition, the Masterplan states that candidates will be track selected prior to entry into primary...training. (3:10) While the Masterplan is not a static document and aircraft procurement plans and/or the timing of track selection are subject to

  1. Clinical applications of iterative reconstruction

    Energy Technology Data Exchange (ETDEWEB)

    Eberl, S. [Royal Prince Alfred Hospital, Camperdown, NSW (Australia). Department of PET and Nuclear Medicine

    1998-03-01

    Expectation maximisation (EM) reconstruction largely eliminates the hot and cold streaking artifacts characteristic of filtered-back projection (FBP) reconstruction around localised hot areas, such as the bladder. It also substantially reduces the problem of decreased inferior wall counts in MIBI myocardial perfusion studies due to ``streaking`` from high liver uptake. Non-uniform attenuation and scatter correction, resolution recovery, anatomical information, e.g. from MRI or CT tracer kinetic modelling, can all be built into the EM reconstruction imaging model. The properties of ordered subset EM (OSEM) have also been used to correct for known patient motion as part of the reconstruction process. These uses of EM are elaborated more fully in some of the other abstracts of this meeting. Currently we use OSEM routinely for: (i) studies where streaking is a problem, including all MIBI myocardial perfusion studies, to avoid hot liver inferior wall artifact, (ii) all whole body FDG PET, all lung V/Q SPECT (which have a short acquisition time) and all gated {sup 201}TI myocardial perfusion studies due to improved noise characteristics of OSEM in these studies; (iii) studies with measured, non-uniform attenuation correction. With the accelerated OSEM algorithm, iterative reconstruction is practical for routine clinical applications and we have found OSEM to provide clearly superior reconstructions for the areas listed above and are investigating its application to other studies. In clinical use, we have not found OSEM to introduce artifacts which would not also occur with FBP, e.g. uncorrected patient motion will cause artifacts with both OSEM and FBP.

  2. Recovery act. Characterizing structural controls of EGS-candidate and conventional geothermal reservoirs in the Great Basin. Developing successful exploration strategies in extended terranes

    Energy Technology Data Exchange (ETDEWEB)

    Faulds, James [Univ. of Nevada, Reno, NV (United States)

    2015-06-25

    We conducted a comprehensive analysis of the structural controls of geothermal systems within the Great Basin and adjacent regions. Our main objectives were to: 1) Produce a catalogue of favorable structural environments and models for geothermal systems. 2) Improve site-specific targeting of geothermal resources through detailed studies of representative sites, which included innovative techniques of slip tendency analysis of faults and 3D modeling. 3) Compare and contrast the structural controls and models in different tectonic settings. 4) Synthesize data and develop methodologies for enhancement of exploration strategies for conventional and EGS systems, reduction in the risk of drilling non-productive wells, and selecting the best EGS sites.

  3. Modified Fractional Variational Iteration Method for Solving the Generalized Time-Space Fractional Schrödinger Equation

    Directory of Open Access Journals (Sweden)

    Baojian Hong

    2014-01-01

    Full Text Available Based on He’s variational iteration method idea, we modified the fractional variational iteration method and applied it to construct some approximate solutions of the generalized time-space fractional Schrödinger equation (GFNLS. The fractional derivatives are described in the sense of Caputo. With the help of symbolic computation, some approximate solutions and their iterative structure of the GFNLS are investigated. Furthermore, the approximate iterative series and numerical results show that the modified fractional variational iteration method is powerful, reliable, and effective when compared with some classic traditional methods such as homotopy analysis method, homotopy perturbation method, adomian decomposition method, and variational iteration method in searching for approximate solutions of the Schrödinger equations.

  4. Advancements and performance of iterative methods in industrial applications codes on CRAY parallel/vector supercomputers

    Energy Technology Data Exchange (ETDEWEB)

    Poole, G.; Heroux, M. [Engineering Applications Group, Eagan, MN (United States)

    1994-12-31

    This paper will focus on recent work in two widely used industrial applications codes with iterative methods. The ANSYS program, a general purpose finite element code widely used in structural analysis applications, has now added an iterative solver option. Some results are given from real applications comparing performance with the tradition parallel/vector frontal solver used in ANSYS. Discussion of the applicability of iterative solvers as a general purpose solver will include the topics of robustness, as well as memory requirements and CPU performance. The FIDAP program is a widely used CFD code which uses iterative solvers routinely. A brief description of preconditioners used and some performance enhancements for CRAY parallel/vector systems is given. The solution of large-scale applications in structures and CFD includes examples from industry problems solved on CRAY systems.

  5. On the safety of ITER accelerators.

    Science.gov (United States)

    Li, Ge

    2013-01-01

    Three 1 MV/40A accelerators in heating neutral beams (HNB) are on track to be implemented in the International Thermonuclear Experimental Reactor (ITER). ITER may produce 500 MWt of power by 2026 and may serve as a green energy roadmap for the world. They will generate -1 MV 1 h long-pulse ion beams to be neutralised for plasma heating. Due to frequently occurring vacuum sparking in the accelerators, the snubbers are used to limit the fault arc current to improve ITER safety. However, recent analyses of its reference design have raised concerns. General nonlinear transformer theory is developed for the snubber to unify the former snubbers' different design models with a clear mechanism. Satisfactory agreement between theory and tests indicates that scaling up to a 1 MV voltage may be possible. These results confirm the nonlinear process behind transformer theory and map out a reliable snubber design for a safer ITER.

  6. Applications of the ergodic iteration theorem

    OpenAIRE

    Zapletal, J.

    2010-01-01

    I prove several natural preservation theorems for the countable support iteration. This solves a question of Roslanowski regarding the preservation of localization properties and greatly simplifies the proofs in the area.

  7. Archimedes' Pi--An Introduction to Iteration.

    Science.gov (United States)

    Lotspeich, Richard

    1988-01-01

    One method (attributed to Archimedes) of approximating pi offers a simple yet interesting introduction to one of the basic ideas of numerical analysis, an iteration sequence. The method is described and elaborated. (PK)

  8. Stability of Jungck-type iterative procedures

    Directory of Open Access Journals (Sweden)

    S. L. Singh

    2005-01-01

    Full Text Available We introduce and discuss the stability of Jungck and Jungck-Mann iterative procedures for a pair of Jungck-Osilike-type maps on an arbitrary set with values in a metric or linear metric space.

  9. Anderson Acceleration for Fixed-Point Iterations

    Energy Technology Data Exchange (ETDEWEB)

    Walker, Homer F. [Worcester Polytechnic Institute, MA (United States)

    2015-08-31

    The purpose of this grant was to support research on acceleration methods for fixed-point iterations, with applications to computational frameworks and simulation problems that are of interest to DOE.

  10. Status and verification strategy for ITER neutronics

    Energy Technology Data Exchange (ETDEWEB)

    Loughlin, Michael, E-mail: michael.loughlin@iter.org [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France); Angelone, Maurizio [Associazione EURATOM-ENEA Sulla Fusione, Via E. Fermi 45, I-00044 Frascati, Roma (Italy); Batistoni, Paola [Associazione EURATOM-ENEA Sulla Fusione, Via E. Fermi 45, I-00044 Frascati, Roma (Italy); JET-EFDA, Culham Science Centre, Abingdon OX14 3DB (United Kingdom); Bertalot, Luciano [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France); Eskhult, Jonas [Studsvik Nuclear AB, SE-611 Nyköping (Sweden); Konno, Chikara [Japan Atomic Energy Agency Tokai-mura, Naka-gun, Ibaraki-ken 319-1195 (Japan); Pampin, Raul [F4E Fusion for Energy, Josep Pla 2, Torres Diagonal Litoral B3, Barcelona 08019 (Spain); Polevoi, Alexei; Polunovskiy, Eduard [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France)

    2014-10-15

    The paper summarizes the current status of neutronics at ITER and a first set of proposals for experimental programmes to be conducted in the early operational life-time of ITER are described for the more crucial areas. These include a TF coils heating benchmark, a streaming benchmark and streaming measurements by activation on ITER itself. Also on ITER the measurement of activated water from triton burn-up should be planned and performed. This will require the measurement of triton burn-up in DD phase. Measurements of neutron flux in the tokamak building during DD operations should also be carried out. The use of JET for verification of shut down dose rate estimates is desirable. Other facilities to examine the production and behaviour of activated corrosion products and the shielding properties of concretes to high energy (6 MeV) gamma-rays are recommended.

  11. Accelerating Iterative Big Data Computing Through MPI

    Institute of Scientific and Technical Information of China (English)

    梁帆; 鲁小亿

    2015-01-01

    Current popular systems, Hadoop and Spark, cannot achieve satisfied performance because of the inefficient overlapping of computation and communication when running iterative big data applications. The pipeline of computing, data movement, and data management plays a key role for current distributed data computing systems. In this paper, we first analyze the overhead of shuffle operation in Hadoop and Spark when running PageRank workload, and then propose an event-driven pipeline and in-memory shuffle design with better overlapping of computation and communication as DataMPI-Iteration, an MPI-based library, for iterative big data computing. Our performance evaluation shows DataMPI-Iteration can achieve 9X∼21X speedup over Apache Hadoop, and 2X∼3X speedup over Apache Spark for PageRank and K-means.

  12. Overview and status of ITER internal components

    Energy Technology Data Exchange (ETDEWEB)

    Merola, Mario, E-mail: mario.merola@iter.org; Escourbiac, Frederic; Raffray, René; Chappuis, Philippe; Hirai, Takeshi; Martin, Alex

    2014-10-15

    Highlights: • Manufacturing technologies for the ITER internal components have been developed. • The Blanket System successfully went through its Final Design Review in April 2013. • The decision to start operation with a Divertor with a full-W armour has been taken. - Abstract: The internal components of ITER are one of the most design and technically challenging components of the ITER machine, and include the Blanket System and the Divertor. The Blanket System successfully went through its Final Design Review in April 2013 and now it is entering into the procurement phase. The design and qualification of the Divertor with a full-tungsten armour was successfully completed and this enabled the decision in November 2013 to start operation with this material option. This paper summarizes the engineering design, the R and D, the technology qualification and procurement status of the Blanket System and of the Divertor of the ITER machine.

  13. Report of a technical evaluation panel on the use of beryllium for ITER plasma facing material and blanket breeder material

    Energy Technology Data Exchange (ETDEWEB)

    Ulrickson, M.A. [ed.] [Sandia National Labs., Albuquerque, NM (United States); Manly, W.D. [Oak Ridge National Lab., TN (United States); Dombrowski, D.E. [Brush Wellman, Inc., Cleveland, OH (United States)] [and others

    1995-08-01

    Beryllium because of its low atomic number and high thermal conductivity, is a candidate for both ITER first wall and divertor surfaces. This study addresses the following: why beryllium; design requirements for the ITER divertor; beryllium supply and unirradiated physical/mechanical property database; effects of irradiation on beryllium properties; tritium issues; beryllium health and safety; beryllium-coolant interactions and safety; thermal and mechanical tests; plasma erosion of beryllium; recommended beryllium grades for ITER plasma facing components; proposed manufacturing methods to produce beryllium parts for ITER; emerging beryllium materials; proposed inspection and maintenance techniques for beryllium components and coatings; time table and costs; and the importance of integrating materials and manufacturing personnel with designers.

  14. In situ synthesis of 3D CoS nanoflake/Ni(OH)₂ nanosheet nanocomposite structure as a candidate supercapacitor electrode.

    Science.gov (United States)

    Li, Songzhan; Wen, Jian; Chen, Tian; Xiong, Liangbin; Wang, Jianbo; Fang, Guojia

    2016-04-08

    A three-dimensional (3D) CoS/Ni(OH)2 nanocomposite structure based on CoS nanoflakes and two-dimensional (2D) Ni(OH)2 nanosheets were in situ synthesized on Ni foam by a whole hydrothermal reaction and electrodeposition process. The 3D CoS/Ni(OH)2 nanocomposite structures demonstrate the combined advantages of a sustained cycle stability of CoS and high specific capacitance from Ni(OH)2. The obtained CoS/Ni(OH)2 nanocomposite structures on Ni foam can directly serve as a binder-free electrode for a supercapacitor. For the 3D CoS/Ni(OH)2 nanocomposite electrode, the high specific capacitance is 1837 F g(-1) at a scan rate of 1 mV s(-1), which is obviously higher than both the bare CoS electrode and Ni(OH)2 electrode. The galvanostatic charge and discharge measurements illustrate that the 3D CoS/Ni(OH)2 nanocomposite electrode possesses excellent cycle stability, and it keeps a 95.8% retention of the initial capacity after 5000 cycles. Electrochemical impedance spectroscopy measurements also confirm that the 3D CoS/Ni(OH)2 nanocomposite electrode has better electrochemical characteristics. These remarkable performances can be attributed to the unique 3D nanoporous structure of CoS/Ni(OH)2 which leads to a large accessible surface area and a high stability during long-term operation. In addition, 2D Ni(OH)2 nanosheets in 3D nanocomposite structures can afford rapid mass transport and a strong synergistic effect of CoS and Ni(OH)2 as individual compositions contribute to the high performance of the nanocomposite structure electrode. These results may promote the design and implementation of nanocomposite structures in advanced supercapacitors.

  15. Liquid lithium self-cooled breeding blanket design for ITER

    Energy Technology Data Exchange (ETDEWEB)

    Kirillov, I.R.; Sidorenkov, S.I. [Research Inst. of Electrophysical Apparatus, St. Petersburg (Russian Federation); Danilov, I.V.; Strebkov, Yu.S. [Research and Development Institute of Power Engineering, 101100 Moscow (Russian Federation); Mattas, R.F.; Hua, T.Q.; Smith, D.L. [Fusion Power Program, Argonne National Laboratory, Chicago, IL 60439 (United States); Gohard, Y. [ITER Garching Joint Work Site, Max-Planck-Institut fur Plasmaphysik, D-85748 Garching bei Munchen (Germany)

    1998-09-01

    To meet the technical objectives of the ITER extended performance phase (EPP) an advanced tritium breeding lithium/vanadium (Li/V) blanket was developed by two home teams (US and RF). The design is based on the use of liquid Li as coolant and breeder and vanadium alloy (V-Cr-Ti) as structural material. The first wall is coated with a beryllium protection layer. Beryllium is also integrated in the blanket for neutron multiplication and improved shielding. The use of tungsten carbide in the primary shield and in vacuum vessel provides adequate protection for toroidal field coils. A self-healing electrical insulator in the form of CaO or AlN coating layer is utilized to reduce MHD pressure drop in the system. To have a self-consistent ITER design, liquid metal cooling of the divertor and vacuum vessel is considered as well. (orig.) 16 refs.

  16. Co-iterative augmented Hessian method for orbital optimization

    CERN Document Server

    Sun, Qiming

    2016-01-01

    Orbital optimization procedure is widely called in electronic structure simulation. To efficiently find the orbital optimization solution, we developed a new second order orbital optimization algorithm, co-iteration augmented Hessian (CIAH) method. In this method, the orbital optimization is embedded in the diagonalization procedure for augmented Hessian (AH) eigenvalue equation. Hessian approximations can be easily employed in this method to improve the computational costs. We numerically performed the CIAH algorithm with SCF convergence of 20 challenging systems and Boys localization of C60 molecule. We found that CIAH algorithm has better SCF convergence and less computational costs than direct inversion iterative subspace (DIIS) algorithm. The numerical tests suggest that CIAH is a stable, reliable and efficient algorithm for orbital optimization problem.

  17. Experiences with iterated traffic microsimulations in Dallas

    CERN Document Server

    Nagel, K

    1997-01-01

    This paper reports experiences with iterated traffic microsimulations in the context of a Dallas study. ``Iterated microsimulations'' here means that the information generated by a microsimulation is fed back into the route planner so that the simulated individuals can adjust their routes to circumvent congestion. This paper gives an overview over what has been done in the Dallas context to better understand the relaxation process, and how to judge the robustness of the results.

  18. A steerable ECRF launcher for ITER

    Energy Technology Data Exchange (ETDEWEB)

    Grunloh, H.; Prater, R.; Doane, J.L.; Moeller, C.P. [General Atomics, San Diego (United States); Makowski, M. [ITER Joint Work Site, Garching (Germany)

    1998-07-01

    A design is proposed to steer the electron cyclotron heating and current drive power for ITER using rotatable, water-cooled mirrors and long-pressure hydraulic actuators, and to accommodate changes in length of the waveguide when the temperatures of the vacuum vessel and the cryostat change using waveguide bellows. An alternative concept is also introduced that requires no moving parts within the ITER cryostat and that utilizes wave reconstruction within the waveguide to effect the steering. (author)

  19. Threshold power and energy confinement for ITER

    Energy Technology Data Exchange (ETDEWEB)

    Takizuka, T.

    1996-12-31

    In order to predict the threshold power for L-H transition and the energy confinement performance in ITER, assembling of database and analyses of them have been progressed. The ITER Threshold Database includes data from 10 divertor tokamaks. Investigation of the database gives a scaling of the threshold power of the form P{sub thr} {proportional_to} B{sub t} n{sub e}{sup 0.75} R{sup 2} {times} (n{sub e} R{sup 2}){sup +-0.25}, which predicts P{sub thr} = 100 {times} 2{sup 0{+-}1} MW for ITER at n{sub e} = 5 {times} 10{sup 19} m{sup {minus}3}. The ITER L-mode Confinement Database has also been expanded by data from 14 tokamaks. A scaling of the thermal energy confinement time in L-mode and ohmic phases is obtained; {tau}{sub th} {approximately} I{sub p} R{sup 1.8} n{sub e}{sup 0.4{sub P{sup {minus}0.73}}}. At the ITER parameter, it becomes about 2.2 sec. For the ignition in ITER, more than 2.5 times of improvement will be required from the L-mode. The ITER H-mode Confinement Database is expanded from data of 6 tokamaks to data of 11 tokamaks. A {tau}{sub th} scaling for ELMy H-mode obtained by a standard regression analysis predicts the ITER confinement time of {tau}{sub th} = 6 {times} (1 {+-} 0.3) sec. The degradation of {tau}{sub th} with increasing n{sub e} R{sup 2} (or decreasing {rho}{sub *}) is not found for ELMy H-mode. An offset linear law scaling with a dimensionally correct form also predicts nearly the same {tau}{sub th} value.

  20. Overview and status of ITER Cryostat manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Bhardwaj, Anil K., E-mail: anil.bhardwaj@iter-india.org [ITER-India, Institute For Plasma Research, A-29, GIDC Electronics Estate, Sector-25, Gandhinagar 382016 (India); Gupta, Girish; Prajapati, Rajnikant; Joshi, Vaibhav; Patel, Mitul; Bhavsar, Jagrut; More, Vipul; Jindal, Mukesh; Bhattacharya, Avik; Jogi, Gourav; Palaliya, Amit; Jha, Saroj; Pandey, Manish; Shukla, Dileep [ITER-India, Institute For Plasma Research, A-29, GIDC Electronics Estate, Sector-25, Gandhinagar 382016 (India); Iyer, Ganesh; Jadhav, Pandurang; Goyal, Dipesh; Desai, Anish [Larsen & Toubro Limited, Heavy Engineering, Hazira Manufacturing Complex, Gujarat (India); Sekachev, I.; Vitupier, Guillaume [ITER Organization, Route de Vinon sur Verdon – CS 90046, 13067 Saint Paul Lez Durance Cedex (France); and others

    2016-11-01

    Highlights: • Manufacturing status of one of the largest and the heaviest fully welded stainless steel vacuum chambers in the world (ITER Cryostat). • Overview of manufacturing stages and its segmentation. • Overview of manufacturing procedures and assembly and installation. - Abstract: One of ITER-India's commitments to the ITER Organization is procurement of the ITER Cryostat. It is a large vacuum vessel (∼29 m dia. and ∼29 m height), which is made up of 304/304 L dual marked stainless steel and has a total mass over 3500 t. The thickness of the vessel wall varies from 50 mm to 190 mm. It is one of the largest and the heaviest fully welded stainless steel vacuum chambers in the world which provides vacuum thermal insulation for the superconducting magnets operating at 4.5 K and for the thermal shield operating at 80 K. It also mechanically supports the magnet system along with the vacuum vessel (VV). The cryostat is designed and constructed according to ASME Section-VIII Division-2 with additional ITER Vacuum Handbook requirements and it is classified as protection important component (PIC-2). Manufacturing of cryostat segments is ongoing in India; sub-assembly of four major sections of the cryostat from the segments will be done at the ITER site in a temporary workshop building and the final assembly will be done in the pit of the tokamak building, the final location. The cryostat manufacturing contract has been awarded to Larsen and Toubro Limited in August 2012 after completion of design [4] and signing of Procurement Arrangement [1] with ITER Organization. Manufacturing of the cryostat was started in January 2014 after approval of the manufacturing drawings and procedures. The temporary workshop of 44 m × 110 m × 26 m in height has been completed in November 2014 at the ITER site with a 200 t crane installed. This paper gives an overview and the status of the cryostat manufacturing.

  1. Efficient iterative adaptive pole placement algorithm

    Institute of Scientific and Technical Information of China (English)

    李俊民; 李靖; 杨磊

    2004-01-01

    An iterative adaptive pole placement algorithm is presented. The stability and the convergence of the algorithm are respectively established. Since one-step iterative formulation in computing controller's parameters is used, the on-line computation cost is greatly reduced with respected to the traditional algorithm. The algorithm with the feed-forward can follow arbitrarily bounded output. The algorithm is also extended to multivariate case. Simulation examples show the efficiency and robustness of the algorithm.

  2. Iterative consolidation of unorganized point clouds.

    Science.gov (United States)

    Liu, Shengjun; Chan, Kwan-Chung; Wang, Charlie C L

    2012-01-01

    Unorganized point clouds obtained from 3D shape acquisition devices usually present noise, outliers, and nonuniformities. The proposed framework consolidates unorganized points through an iterative procedure of interlaced downsampling and upsampling. Selection operations remove outliers while preserving geometric details. The framework improves the uniformity of points by moving the downsampled particles and refining point samples. Surface extrapolation fills missed regions. Moreover, an adaptive sampling strategy speeds up the iterations. Experimental results demonstrate the framework's effectiveness.

  3. Accelerated Schwarz iterations for Helmholtz equation

    Science.gov (United States)

    Nagid, Nabila; Belhadj, Hassan; Amattouch, Mohamed Ridouan

    2017-01-01

    In this paper, the Restricted additive Schwarz (RAS) method is applied to solve Helmholtz equation. To accelerate the RAS iterations, we propose to apply the vector ɛ-algorithm. Some convergence analysis of the proposed method is presented, and applied succeffully to Helmholtz problem. The obtained results show the efficiency of the proposed approach. Moreover, the algorithm yields much faster convergence than the classical Schwarz iterations.

  4. IMM Iterated Extended Particle Filter Algorithm

    OpenAIRE

    Yang Wan; Shouyong Wang; Xing Qin

    2013-01-01

    In order to solve the tracking problem of radar maneuvering target in nonlinear system model and non-Gaussian noise background, this paper puts forward one interacting multiple model (IMM) iterated extended particle filter algorithm (IMM-IEHPF). The algorithm makes use of multiple modes to model the target motion form to track any maneuvering target and each mode uses iterated extended particle filter (IEHPF) to deal with the state estimation problem of nonlinear non-Gaussian system. IEH...

  5. Novel aspects of plasma control in ITER

    Energy Technology Data Exchange (ETDEWEB)

    Humphreys, D.; Jackson, G.; Walker, M.; Welander, A. [General Atomics P.O. Box 85608, San Diego, California 92186-5608 (United States); Ambrosino, G.; Pironti, A. [CREATE/University of Naples Federico II, Napoli (Italy); Vries, P. de; Kim, S. H.; Snipes, J.; Winter, A.; Zabeo, L. [ITER Organization, St. Paul Lez durance Cedex (France); Felici, F. [Eindhoven University of Technology, Eindhoven (Netherlands); Kallenbach, A.; Raupp, G.; Treutterer, W. [Max-Planck Institut für Plasmaphysik, Garching (Germany); Kolemen, E. [Princeton Plasma Physics Laboratory, Princeton, New Jersey 08543-0451 (United States); Lister, J.; Sauter, O. [Centre de Recherches en Physique des Plasmas, Ecole Polytechnique Federale de Lausanne, Lausanne (Switzerland); Moreau, D. [CEA, IRFM, 13108 St. Paul-lez Durance (France); Schuster, E. [Lehigh University, Bethlehem, Pennsylvania (United States)

    2015-02-15

    ITER plasma control design solutions and performance requirements are strongly driven by its nuclear mission, aggressive commissioning constraints, and limited number of operational discharges. In addition, high plasma energy content, heat fluxes, neutron fluxes, and very long pulse operation place novel demands on control performance in many areas ranging from plasma boundary and divertor regulation to plasma kinetics and stability control. Both commissioning and experimental operations schedules provide limited time for tuning of control algorithms relative to operating devices. Although many aspects of the control solutions required by ITER have been well-demonstrated in present devices and even designed satisfactorily for ITER application, many elements unique to ITER including various crucial integration issues are presently under development. We describe selected novel aspects of plasma control in ITER, identifying unique parts of the control problem and highlighting some key areas of research remaining. Novel control areas described include control physics understanding (e.g., current profile regulation, tearing mode (TM) suppression), control mathematics (e.g., algorithmic and simulation approaches to high confidence robust performance), and integration solutions (e.g., methods for management of highly subscribed control resources). We identify unique aspects of the ITER TM suppression scheme, which will pulse gyrotrons to drive current within a magnetic island, and turn the drive off following suppression in order to minimize use of auxiliary power and maximize fusion gain. The potential role of active current profile control and approaches to design in ITER are discussed. Issues and approaches to fault handling algorithms are described, along with novel aspects of actuator sharing in ITER.

  6. Novel aspects of plasma control in ITER

    Science.gov (United States)

    Humphreys, D.; Ambrosino, G.; de Vries, P.; Felici, F.; Kim, S. H.; Jackson, G.; Kallenbach, A.; Kolemen, E.; Lister, J.; Moreau, D.; Pironti, A.; Raupp, G.; Sauter, O.; Schuster, E.; Snipes, J.; Treutterer, W.; Walker, M.; Welander, A.; Winter, A.; Zabeo, L.

    2015-02-01

    ITER plasma control design solutions and performance requirements are strongly driven by its nuclear mission, aggressive commissioning constraints, and limited number of operational discharges. In addition, high plasma energy content, heat fluxes, neutron fluxes, and very long pulse operation place novel demands on control performance in many areas ranging from plasma boundary and divertor regulation to plasma kinetics and stability control. Both commissioning and experimental operations schedules provide limited time for tuning of control algorithms relative to operating devices. Although many aspects of the control solutions required by ITER have been well-demonstrated in present devices and even designed satisfactorily for ITER application, many elements unique to ITER including various crucial integration issues are presently under development. We describe selected novel aspects of plasma control in ITER, identifying unique parts of the control problem and highlighting some key areas of research remaining. Novel control areas described include control physics understanding (e.g., current profile regulation, tearing mode (TM) suppression), control mathematics (e.g., algorithmic and simulation approaches to high confidence robust performance), and integration solutions (e.g., methods for management of highly subscribed control resources). We identify unique aspects of the ITER TM suppression scheme, which will pulse gyrotrons to drive current within a magnetic island, and turn the drive off following suppression in order to minimize use of auxiliary power and maximize fusion gain. The potential role of active current profile control and approaches to design in ITER are discussed. Issues and approaches to fault handling algorithms are described, along with novel aspects of actuator sharing in ITER.

  7. Algorithmic Optimisations for Iterative Deconvolution Methods

    OpenAIRE

    Welk, Martin; Erler, Martin

    2013-01-01

    We investigate possibilities to speed up iterative algorithms for non-blind image deconvolution. We focus on algorithms in which convolution with the point-spread function to be deconvolved is used in each iteration, and aim at accelerating these convolution operations as they are typically the most expensive part of the computation. We follow two approaches: First, for some practically important specific point-spread functions, algorithmically efficient sliding window or list processing tech...

  8. Targeting modular polyketide synthases with iteratively acting acyltransferases from metagenomes of uncultured bacterial consortia.

    Science.gov (United States)

    Piel, Jörn; Hui, Dequan; Fusetani, Nobuhiro; Matsunaga, Shigeki

    2004-09-01

    Bacterial type I polyketide synthases (PKSs) produce a wide range of biomedically important secondary metabolites. These enzymes possess a modular structure that can be genetically re-engineered to yield novel drug candidates not found in nature. Recently, we have reported the putative pederin PKS from an uncultured bacterial symbiont of Paederus fuscipes beetles. It belongs to an architecturally unusual PKS group, the members of which contain iteratively acting acyltransferases that are not integrated into the PKS modules but are encoded by isolated genes. As these systems are rare, often contain additional unusual features and are of smaller size than regular PKSs, the development of a method for the targeted isolation of new group members would be of great interest. Here, we present a phylogenetic approach to identify these systems rapidly in highly complex metagenomic DNA samples. To demonstrate its practical value, we located two pederin-type PKS systems putatively involved in the biosynthesis of antitumour polyketides in the metagenomic DNA of beetles, sponges and their uncultivated bacterial symbionts.

  9. Non-iterative phase hologram computation for low speckle holographic image projection

    OpenAIRE

    Ürey, Hakan; Ulusoy, Erdem; Mengü, Deniz

    2016-01-01

    Phase-only spatial light modulators (SLMs) are widely used in holographic display applications, including holographic image projection (HIP). Most phase computer generated hologram (CGH) calculation algorithms have an iterative structure with a high computational load, and also are prone to speckle noise, as a result of the random phase terms applied on the desired images to mitigate the encoding noise. In this paper, we present a non-iterative algorithm, where simple Discrete Fourier Transfo...

  10. An Iterative Construction of Solutions of the TAP Equations for the Sherrington-Kirkpatrick Model

    Science.gov (United States)

    Bolthausen, Erwin

    2014-01-01

    We propose an iterative scheme for the solutions of the TAP-equations in the Sherrington-Kirkpatrick model which is shown to converge up to and including the de Almeida-Thouless line. The main tool is a representation of the iterations which reveals an interesting structure of them. This representation does not depend on the temperature parameter, but for temperatures below the de Almeida-Thouless line, it contains a part which does not converge to zero in the limit.

  11. Development and test of prototype components for ITER; Entwicklung und Test von Prototypkomponenten fuer ITER

    Energy Technology Data Exchange (ETDEWEB)

    Biel, Wolfgang; Behr, Wilfried; Castano-Bardawil, David; and others

    2015-08-15

    The scientific program of the project is divided into the following partial projects: (1.) ITER Diagnostic Port Plug for the charge-exchange spectroscopy (CXRS) with the subthemes: (a) Development of prototypes for critical mechanical components, (b) development of a roboter for the laser welding of vacuum seals and pipings at the Port Plug, (c) mirror studies, (d) CXRS prototype spectrometer, (2.) ITER tritium retention diagnostics (TR), (3.) ITER disruption mitigation ventile (DMV).

  12. ITER Remote Maintenance System (IRMS) lifecycle management

    Energy Technology Data Exchange (ETDEWEB)

    Tesini, Alessandro, E-mail: alessandro.tesini@iter.org [ITER Organization, CS 90 046, 13067 St. Paul Lez Durance Cedex (France); Otto' , Bede [Oxford Technologies Ltd, 7, Nuffield Way, Abingdon, Oxon OX14 1RJ (United Kingdom); Blight, John [FAAST 31c Allee de la Granette, 13600 Ceyreste (France); Choi, Chang-Hwan; Friconneau, Jean-Pierre; Gotewal, Krishan Kumar; Hamilton, David [ITER Organization, CS 90 046, 13067 St. Paul Lez Durance Cedex (France); Heckendorn, Frank [FD Technologies, PO Box 6686, Aiken, SC (United States); Martins, Jean-Pierre [ITER Organization, CS 90 046, 13067 St. Paul Lez Durance Cedex (France); Marty, Thomas [Westinghouse, 122, avenue de Hambourg, 13008 Marseille (France); Nakahira, Masataka; Palmer, Jim; Subramanian, Rajendran [ITER Organization, CS 90 046, 13067 St. Paul Lez Durance Cedex (France)

    2011-10-15

    The availability of the ITER machine to perform its scientific program is strongly dependent on the performance of the different Remote Handling (RH) systems constituting the ITER Remote Maintenance System (IRMS). The lifecycle of the IRMS will largely exceed 40 years from initial concept design and proof testing through to machine decommissioning. Such a long lifecycle requires that a rigorous approach is put in place to guarantee the technical capabilities of the highly innovative IRMS, its efficiency and its availability. For this purpose, an IRMS System Engineering and IRMS lifecycle management approach has been adopted by ITER. The approach aims at ensuring the IRMS full operability and availability at an acceptable cost of ownership over the full ITER machine assembly and operations period. The IRMS lifecycle management method described in this paper covers such subjects as specific requirements for IRMS design reviews, monitoring during manufacture, factory and site acceptance testing, integrated commissioning, decontamination, maintenance and re-qualification strategies, requirements for Integrated Logistical Support during operations. The updating and implementation of the IRMS lifecycle strategy and this procedure will be managed and monitored by the Remote Handling Integrated Product Team (RH-IPT). Although developed for the IRMS, the basic principles and procedures of lifecycle management could be applied to other ITER plant systems whose reliability and availability will be essential for the continued operation of the ITER machine.

  13. Next-generation sequencing of 100 candidate genes in young victims of suspected sudden cardiac death with structural abnormalities of the heart

    DEFF Research Database (Denmark)

    Hertz, C L; Christiansen, S L; Ferrero-Miliani, Laura;

    2016-01-01

    BACKGROUND: In sudden, unexpected, non-traumatic death in young individuals, structural abnormalities of the heart are frequently identified at autopsy. However, the findings may be unspecific and cause of death may remain unclear. A significant proportion of these cases are most likely caused...... by inherited cardiac diseases, and the cases are categorized as sudden cardiac death (SCD). The purpose of this study was to explore the added diagnostic value of genetic testing by next-generation sequencing (NGS) of a broad gene panel, as a supplement to the traditional forensic investigation in cases...... with non-diagnostic structural abnormalities of the heart. METHODS AND RESULTS: We screened 72 suspected SCD cases (

  14. An Iterative Method for Problems with Multiscale Conductivity

    Directory of Open Access Journals (Sweden)

    Hyea Hyun Kim

    2012-01-01

    Full Text Available A model with its conductivity varying highly across a very thin layer will be considered. It is related to a stable phantom model, which is invented to generate a certain apparent conductivity inside a region surrounded by a thin cylinder with holes. The thin cylinder is an insulator and both inside and outside the thin cylinderare filled with the same saline. The injected current can enter only through the holes adopted to the thin cylinder. The model has a high contrast of conductivity discontinuity across the thin cylinder and the thickness of the layer and the size of holes are very small compared to the domain of the model problem. Numerical methods for such a model require a very fine mesh near the thin layer to resolve the conductivity discontinuity. In this work, an efficient numerical method for such a model problem is proposed by employing a uniform mesh, which need not resolve the conductivity discontinuity. The discrete problem is then solved by an iterative method, where the solution is improved by solving a simple discrete problem with a uniform conductivity. At each iteration, the right-hand side is updated by integrating the previous iterate over the thin cylinder. This process results in a certain smoothing effect on microscopic structures and our discrete model can provide a more practical tool for simulating the apparent conductivity. The convergence of the iterative method is analyzed regarding the contrast in the conductivity and the relative thickness of the layer. In numerical experiments, solutions of our method are compared to reference solutions obtained from COMSOL, where very fine meshes are used to resolve the conductivity discontinuity in the model. Errors of the voltage in L2 norm follow O(h asymptotically and the current density matches quitewell those from the reference solution for a sufficiently small mesh size h. The experimental results present a promising feature of our approach for simulating the apparent

  15. Structural and optical properties of ZnO nanostructures grown by aerosol spray pyrolysis: Candidates for room temperature methane and hydrogen gas sensing

    Science.gov (United States)

    Motaung, D. E.; Mhlongo, G. H.; Kortidis, I.; Nkosi, S. S.; Malgas, G. F.; Mwakikunga, B. W.; Ray, S. Sinha; Kiriakidis, G.

    2013-08-01

    We report on the synthesis of ZnO films by aerosol spray pyrolysis method at different deposition times. The surface morphology, crystal structure and the cross-sectional analysis of the prepared ZnO films were characterized by X-ray diffraction (XRD), focused ion beam scanning electron microscopy (FIB-SEM), atomic force microscopy (AFM) and high resolution transmission electron microscopy (HR-TEM). XRD analysis revealed that the ZnO films are polycrystalline in nature. Structural analysis exploiting cross-sectional TEM profile showed that the films composed of nano-particles and columnar structures growing perpendicular to the substrate. AFM revealed that the columnar structures have a higher surface roughness as compared to the nanoparticles. The effect of ZnO crystallite size and crystallinity on the gas sensing performance of hydrogen and methane gases was also evaluated. Sensing film based on ZnO nanoparticles has numerous advantages in terms of its reliability and high sensitivity. These sensing materials revealed an improved response to methane and hydrogen gases at room temperature due to their high surface area, indicating their possible application as a gas sensor.

  16. Structural and optical properties of ZnO nanostructures grown by aerosol spray pyrolysis: Candidates for room temperature methane and hydrogen gas sensing

    Energy Technology Data Exchange (ETDEWEB)

    Motaung, D.E., E-mail: dmotaung@csir.co.za [DST/CSIR Nanotechnology Innovation Centre, National Centre for Nano-Structured Materials, Council for Scientific and Industrial Research, P. O. Box 395, Pretoria 0001 (South Africa); Mhlongo, G.H., E-mail: gmhlongo@csir.co.za [DST/CSIR Nanotechnology Innovation Centre, National Centre for Nano-Structured Materials, Council for Scientific and Industrial Research, P. O. Box 395, Pretoria 0001 (South Africa); Kortidis, I. [Transparent Conductive Materials Lab, Institute of Electronic Structure and Laser, Foundation for Research and Technology Hellas, 100N. Plastira str., Vassilika Vouton, 70013 Heraklion, Crete (Greece); Nkosi, S.S., E-mail: skosi@csir.co.za [CSIR-National Laser Centre, 626 Meiring Naude Rd, Brummeria, Pretoria 0001 (South Africa); School of Physics, University of Witwatersrand, Private Bag X3, Johannesburg 2030 (South Africa); Malgas, G.F.; Mwakikunga, B.W.; Ray, S.Sinha [DST/CSIR Nanotechnology Innovation Centre, National Centre for Nano-Structured Materials, Council for Scientific and Industrial Research, P. O. Box 395, Pretoria 0001 (South Africa); Kiriakidis, G., E-mail: kiriakid@iesl.forth.gr [Transparent Conductive Materials Lab, Institute of Electronic Structure and Laser, Foundation for Research and Technology Hellas, 100N. Plastira str., Vassilika Vouton, 70013 Heraklion, Crete (Greece); University of Crete, Department of Physics, 710 03 Heraklion, Crete (Greece)

    2013-08-15

    We report on the synthesis of ZnO films by aerosol spray pyrolysis method at different deposition times. The surface morphology, crystal structure and the cross-sectional analysis of the prepared ZnO films were characterized by X-ray diffraction (XRD), focused ion beam scanning electron microscopy (FIB-SEM), atomic force microscopy (AFM) and high resolution transmission electron microscopy (HR-TEM). XRD analysis revealed that the ZnO films are polycrystalline in nature. Structural analysis exploiting cross-sectional TEM profile showed that the films composed of nano-particles and columnar structures growing perpendicular to the substrate. AFM revealed that the columnar structures have a higher surface roughness as compared to the nanoparticles. The effect of ZnO crystallite size and crystallinity on the gas sensing performance of hydrogen and methane gases was also evaluated. Sensing film based on ZnO nanoparticles has numerous advantages in terms of its reliability and high sensitivity. These sensing materials revealed an improved response to methane and hydrogen gases at room temperature due to their high surface area, indicating their possible application as a gas sensor.

  17. Structural and optical properties of ZnO nanostructures grown by aerosol spray pyrolysis: candidates for room temperature methane and hydrogen gas sensing

    CSIR Research Space (South Africa)

    Motaung, DE

    2013-08-01

    Full Text Available We report on the synthesis of ZnO films by aerosol spray pyrolysis method at different deposition times.The surface morphology, crystal structure and the cross-sectional analysis of the prepared ZnO filmswere characterized by X-ray diffraction (XRD...

  18. The role of the Wigner distribution function in iterative ptychography

    CERN Document Server

    Edo, Tega Boro

    2015-01-01

    Ptychography employs a set of diffraction patterns that capture redundant information about an illuminated specimen as a localized beam is moved over the specimen. The robustness of this method comes from the redundancy of the dataset that in turn depends on the amount of oversampling and the form of the illumination. Although the role of oversampling in ptychography is fairly well understood, the same cannot be said of the illumination structure. This paper provides a vector space model of ptychography that accounts for the illumination structure in a way that highlights the role of the Wigner distribution function in iterative ptychography.

  19. Electromagnetic Analysis For The Design Of ITER Diagnostic Port Plugs During Plasma Disruptions

    Energy Technology Data Exchange (ETDEWEB)

    Zhai, Y

    2014-03-03

    ITER diagnostic port plugs perform many functions including structural support of diagnostic systems under high electromagnetic loads while allowing for diagnostic access to plasma. The design of diagnotic equatorial port plugs (EPP) are largely driven by electromagnetic loads and associate response of EPP structure during plasma disruptions and VDEs. This paper summarizes results of transient electromagnetic analysis using Opera 3d in support of the design activities for ITER diagnostic EPP. A complete distribution of disruption loads on the Diagnostic First Walls (DFWs). Diagnostic Shield Modules (DSMs) and the EPP structure, as well as impact on the system design integration due to electrical contact among various EPP structural components are discussed.

  20. Electromagnetic Analysis of ITER Diagnostic Equatorial Port Plugs During Plasma Disruptions

    Energy Technology Data Exchange (ETDEWEB)

    Y. Zhai, R. Feder, A. Brooks, M. Ulrickson, C.S. Pitcher and G.D. Loesser

    2012-08-27

    ITER diagnostic port plugs perform many functionsincluding structural support of diagnostic systems under high electromagnetic loads while allowing for diagnostic access to the plasma. The design of diagnostic equatorial port plugs (EPP) are largely driven by electromagnetic loads and associate responses of EPP structure during plasma disruptions and VDEs. This paper summarizes results of transient electromagnetic analysis using Opera 3d in support of the design activities for ITER diagnostic EPP. A complete distribution of disruption loads on the Diagnostic First Walls (DFWs), Diagnostic Shield Modules (DSMs) and the EPP structure, as well as impact on the system design integration due to electrical contact among various EPP structural components are discussed.

  1. Simulation of dust production in ITER transient events

    Energy Technology Data Exchange (ETDEWEB)

    Pestchanyi, S. [Forschungszentrum Karlsruhe (Germany)

    2007-07-01

    The tritium retention problem is a critical issue for the tokamak ITER performance. Tritium is trapped in redeposited T-C layers and at the surface of carbon dust, where it is retained in form of various hydrocarbons. The area of dust surface and hence, the amount of tritium deposited on the surface depends on the dust amount and of the dust sizes. The carbon dust appears as a result of brittle destruction at the surface of the carbon fibre composite (CFC) which is now the reference armour material for the most loaded part of tokamak divertor. Stationary heat flux on the ITER divertor armour does not cause its brittle destruction and does not produce dust. However, according to the modern understanding of tokamak fusion devices performance, the most attractive regime of ITER operation is the ELMy H mode. This regime is associated with a repetitive short time increase of heat flux at the CFC divertor armour of 2-3 orders of magnitude over its stationary value during edge localized modes (ELMs). Under influence of these severe heat shocks CFC armour can crack due to the thermostress, producing a dust of carbon. Besides, a carbon dust produced during disruptions due to brittle destruction of the armour under influence of thermoshock. Most of the modern tokamaks do not produce the ELMs powerful enough to cause CFC brittle destruction at the divertor surface, except of very special regimes in JET. This is why the CFC erosion and dust production could be investigated now only theoretically and experimentally in plasma guns and electron beam facilities. Simulation of the CFC brittle destruction has been done using the code PEGASUS already developed and tested in FZK for simulation of erosion for ITER candidate materials under the heat shocks. After upgrades the code was used for simulation of the amount of carbon dust particles and of the distribution of their sizes. The code has been tested against available experimental data from the plasma gun MK-200UG and from the

  2. LALF32-51 -E7, a HPV-16 therapeutic vaccine candidate, forms protein body-like structures when expressed in Nicotiana benthamiana leaves.

    Science.gov (United States)

    Yanez, Romana J R; Lamprecht, Renate; Granadillo, Milaid; Torrens, Isis; Arcalís, Elsa; Stöger, Eva; Rybicki, Edward P; Hitzeroth, Inga I

    2017-07-22

    High-risk human papillomaviruses (HPVs) cause cervical cancer, and while there are good prophylactic vaccines on the market, these are ineffective against established infections, creating a clear need for therapeutic vaccines. The HPV E7 protein is one of the essential oncoproteins for the onset and maintenance of malignancy and is therefore an ideal therapeutic vaccine target. We fused the HPV-16 E7 protein to the Limulus polyphemus antilipopolysaccharide factor (LALF32-51 ), a small hydrophobic peptide that can penetrate cell membranes and that has immunomodulatory properties. LALF32-51 -E7 was transiently expressed in Nicotiana benthamiana, and we previously determined that it accumulated better when targeted to chloroplasts compared to being localized in the cytoplasm. Subsequently, we aimed to prove whether LALF32-51 -E7 was indeed associated with the chloroplasts by determining its subcellular localization. The LALF32-51 -E7 gene was fused to one encoding enhanced GFP to generate a LG fusion protein, and localization was determined by confocal laser scanning microscopy and transmission electron microscopy (TEM). The fluorescence observed from chloroplast-targeted LG was distinctively different from that of the cytoplasmic LG. Small spherical structures resembling protein bodies (PBs) were seen that clearly localized with the chloroplasts. Larger but less abundant PB-like structures were also seen for the cytoplasmic LG. PB-like structure formation was confirmed for both LG and LALF32-51 -E7 by TEM. LALF32-51 -E7 was indeed targeted to the chloroplasts by the chloroplast transit peptide used in this study, and it formed aggregated PB-like structures. This study could open a new avenue for the use of LALF32-51 as a PB-inducing peptide. © 2017 The Authors. Plant Biotechnology Journal published by Society for Experimental Biology and The Association of Applied Biologists and John Wiley & Sons Ltd.

  3. PREFACE: Progress in the ITER Physics Basis

    Science.gov (United States)

    Ikeda, K.

    2007-06-01

    I would firstly like to congratulate all who have contributed to the preparation of the `Progress in the ITER Physics Basis' (PIPB) on its publication and express my deep appreciation of the hard work and commitment of the many scientists involved. With the signing of the ITER Joint Implementing Agreement in November 2006, the ITER Members have now established the framework for construction of the project, and the ITER Organization has begun work at Cadarache. The review of recent progress in the physics basis for burning plasma experiments encompassed by the PIPB will be a valuable resource for the project and, in particular, for the current Design Review. The ITER design has been derived from a physics basis developed through experimental, modelling and theoretical work on the properties of tokamak plasmas and, in particular, on studies of burning plasma physics. The `ITER Physics Basis' (IPB), published in 1999, has been the reference for the projection methodologies for the design of ITER, but the IPB also highlighted several key issues which needed to be resolved to provide a robust basis for ITER operation. In the intervening period scientists of the ITER Participant Teams have addressed these issues intensively. The International Tokamak Physics Activity (ITPA) has provided an excellent forum for scientists involved in these studies, focusing their work on the high priority physics issues for ITER. Significant progress has been made in many of the issues identified in the IPB and this progress is discussed in depth in the PIPB. In this respect, the publication of the PIPB symbolizes the strong interest and enthusiasm of the plasma physics community for the success of the ITER project, which we all recognize as one of the great scientific challenges of the 21st century. I wish to emphasize my appreciation of the work of the ITPA Coordinating Committee members, who are listed below. Their support and encouragement for the preparation of the PIPB were

  4. Analysis of the mechanical behaviour of the ITER magnet system

    Energy Technology Data Exchange (ETDEWEB)

    Jong, C.T.J.

    1996-03-01

    The International Thermonuclear Experimental Reactor (ITER) is a tokamak fusion device with the objective of demonstrating controlled ignition and an extended burn for a duration sufficient to achieve stationary conditions. The design of ITER will be based on extensive new design work supported by new physical and technological results. As part of the ITER Engineering Design Activities, the mechanical behaviour of the toroidal field coil (TF coil) system during normal operating conditions and fault conditions has to be analyzed. The displacements and/or stresses in the components must be limited to prevent mechanical failure of parts of the overall structure. These Engineering Design Activities are supported by R and D programs in the European Union. This final report describes the work carried out by ECN to develop a finite element model (FE model) of the TF-coil system which is suitable for the analysis of the mechanical behaviour and presents results obtained with this model. For the analysis of the mechanical behaviour, a large three dimensional (3D) non-linear finite element model has been developed. With this FE model a large number of load cases has been analyzed which correspond with several time points during multiple pulses. (orig./WL).

  5. Preliminary design of the ITER ECH Upper Launcher

    Energy Technology Data Exchange (ETDEWEB)

    Strauss, D., E-mail: dirk.strauss@kit.edu [Karlsruhe Institute of Technology, Assoc. KIT-EURATOM, D-76021 Karlsruhe (Germany); Aiello, G. [Karlsruhe Institute of Technology, Assoc. KIT-EURATOM, D-76021 Karlsruhe (Germany); Chavan, R. [Centre de Recherches en Physique des Plasmas, CRPP–EPFL, CH-1015 Lausanne (Switzerland); Cirant, S. [Istituto di Fisica del Plasma CNR, Euratom Association, 20125 Milano (Italy); Baar, M. de [FOM, Van Vollenhovenlaan 659, 3527 JP, Utrecht (Netherlands); Farina, D. [Istituto di Fisica del Plasma CNR, Euratom Association, 20125 Milano (Italy); Gantenbein, G. [Karlsruhe Institute of Technology, Assoc. KIT-EURATOM, D-76021 Karlsruhe (Germany); Goodman, T.P. [Centre de Recherches en Physique des Plasmas, CRPP–EPFL, CH-1015 Lausanne (Switzerland); Henderson, M.A. [ITER Organization, 13108 Saint-Paul-lez-Durance (France); Kasparek, W. [Institut für Plasmaforschung, IPF, D-70569 Stuttgart (Germany); Kleefeldt, K. [Karlsruhe Institute of Technology, Assoc. KIT-EURATOM, D-76021 Karlsruhe (Germany); Landis, J.-D. [Centre de Recherches en Physique des Plasmas, CRPP–EPFL, CH-1015 Lausanne (Switzerland); Meier, A. [Karlsruhe Institute of Technology, Assoc. KIT-EURATOM, D-76021 Karlsruhe (Germany); Moro, A.; Platania, P. [Istituto di Fisica del Plasma CNR, Euratom Association, 20125 Milano (Italy); Plaum, B. [Institut für Plasmaforschung, IPF, D-70569 Stuttgart (Germany); Poli, E. [Max-Planck-IPP, Euratom Association, D-85748 Garching (Germany); Ramponi, G. [Istituto di Fisica del Plasma CNR, Euratom Association, 20125 Milano (Italy); Ronden, D. [FOM, Van Vollenhovenlaan 659, 3527 JP, Utrecht (Netherlands); Saibene, G. [Fusion for Energy, Barcelona (Spain); and others

    2013-11-15

    Highlights: • Front steering mirror design. • Plasma facing blanket shield module/first wall panel design. • Fixed frequency torus CVD diamond window serving as first tritium barrier. • Prototypes and tests of the above key components in the Launcher Handling and Testing Facility. -- Abstract: The design of the ITER electron cyclotron launchers recently reached the preliminary design level - the last major milestone before design finalization. The ITER ECH system contains 24 installed gyrotrons providing a maximum ECH injected power of 20 MW through transmission lines towards the tokamak. There are two EC launcher types both using a front steering mirror; one equatorial launcher (EL) for plasma heating and four upper launchers (UL) for plasma mode stabilization (neoclassical tearing modes and the sawtooth instability). A wide steering angle range of the ULs allows focusing of the beam on magnetic islands which are expected on the rational magnetic flux surfaces q = 1 (sawtooth instability), q = 3/2 and q = 2 (NTMs). In this paper the preliminary design of the ITER ECH UL is presented, including the optical system and the structural components. Highlights of the design include the torus CVD-diamond windows, the frictionless, front steering mechanism and the plasma facing blanket shield module (BSM). Numerical simulations as well as prototype tests are used to verify the design.

  6. Qualification of the Joints for the ITER Central Solenoid

    Energy Technology Data Exchange (ETDEWEB)

    Martovetsky, N; Berryhill, A; Kenney, S

    2011-09-01

    The ITER Central Solenoid has 36 interpancake joints, 12 bus joints, and 12 feeder joints in the magnet. The joints are required to have resistance below 4 nOhm at 45 kA at 4.5 K. The US ITER Project Office developed two different types of interpancake joints with some variations in details in order to find a better design, qualify the joints, and establish a fabrication process. We built and tested four samples of the sintered joints and two samples with butt-bonded joints (a total of eight joints). Both designs met the specifications. Results of the joint development, test results, and selection of the baseline design are presented and discussed in the paper. The ITER Central Solenoid (CS) consists of six modules. Each module is composed of six wound hexapancakes and one quadrapancake. The multipancakes are connected electrically and hydraulically by in-line interpancake joints. The joints are located at the outside diameter (OD) of the module. Cable in conduit conductor (CICC) high-current joints are critical elements in the CICC magnets. In addition to low resistivity, the CS joints must fit a space envelope equivalent to the regular conductor cross section and must have low hydraulic impedance and enough structural strength to withstand the hoop and compressive forces during operation, including cycling. This paper is the continuation of the work reported on the intermodule joints.

  7. An Exploration of Advanced X-Divertors on ITER

    CERN Document Server

    Covele, Brent; Kotschenreuther, Mike; Mahajan, Swadesh

    2013-01-01

    It is found that the X-Divertor (XD) configuration [1-3] can be made with the conventional PF coil set on ITER[4], where all PF coils are outside the TF coils. Desirable configurations are possible where the PF currents are below the present maximum design limits on ITER, and where the baseline divertor cassette is used. It is possible that the XD could be used to assist in high-power operation on ITER, but some further issues need examination. Note that the increased major radius of the Super X-Divertor (SXD) [5-8] is not a feature of the XD geometry. In addition, we present an XD configuration for K-DEMO [9], to demonstrate that it is also possible to attain the XD configuration in advanced tokamak reactors with all PF coils outside the TF coils. The results given here for the XD are far more encouraging than recent calculations by Lackner and Zohm [10] for the Snowflake [11,12], where the required high PF currents represent a major technological challenge. The magnetic field structure in the outboard diver...

  8. Progress of ITER full tungsten divertor technology qualification in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Ezato, K., E-mail: ezato.koichiro@jaea.go.jp [Japan Atomic Energy Agency, 801-1, Mukoyma, Naka-shi, Ibaraki (Japan); Suzuki, S.; Seki, Y.; Mohri, K.; Yokoyama, K. [Japan Atomic Energy Agency, 801-1, Mukoyma, Naka-shi, Ibaraki (Japan); Escourbiac, F.; Hirai, T. [ITER Organization, Route de Vinon-sur-Verdon, CS 90 046, 13067 St. Paul Lez Durance Cedex (France); Kuznetcov, V. [NIIEFA, 3 doroga na Metallostroy, Metallostroy, St. Petersburg 196641 (Russian Federation)

    2015-10-15

    Highlights: • JAEA has demonstrated tungsten monoblock technology for ITER divertor that needs to withstand the repetitive heat load as high as 20 MW/m{sup 2}. This includes as follows; • Bonding technologies between W and Cu interlayer, and between Cu interlayer and CuCrZr tube. • Non-destructive examination techniques, especially, ultrasonic testing method, and. • Load carrying capability of W monoblock attachment to support structure of ITER divertor. - Abstract: Japan Atomic Energy Agency (JAEA) is in progress for technology qualification toward full-tungsten (W) ITER divertor outer vertical target (OVT), especially, tungsten monoblock technology that needs to withstand the repetitive heat load as high as 20 MW/m{sup 2}. To demonstrate the armor heat sink bonding technology and heat removal capability, 6 small-scale W monoblock mock-ups manufactured by different bonding technologies using different W materials in addition to 4 full-scale prototype plasma-facing units (PFUs). After non-destructive test, the W components were tested under high heat flux (HHF) in ITER Divertor Test Facility (IDTF) at NIIEFA. Consequently, all of the W monoblocks endured the repetitive heat load at 20 MW/m{sup 2} for 1000 cycles (requirements 20 MW/m{sup 2} for 300 cycles) without any failure. In addition to the armor to heat sink joints, the load carrying capability test on the W monoblock with a leg attachment was carried out. In uniaxial tensile test, all of the W monoblock attachments with different bonding technologies such as brazing and HIPping withstand the tensile load exceeding 20 kN that is the value more than twice the design value. The failures occurred at the leg attachments or the W monoblocks, rather than the bonding interface of the W monoblocks to the leg attachment.

  9. ITER (International Thermonuclear Experimental Reactor) shield and blanket work package report

    Energy Technology Data Exchange (ETDEWEB)

    1988-06-01

    This report summarizes nuclear-related work in support of the US effort for the International Thermonuclear Experimental Reactor (ITER) Study. The purpose of this work was to prepare for the first international ITER workshop devoted to defining a basic ITER concept that will serve as a basis for an indepth conceptual design activity over the next 2-1/2 years. Primary tasks carried out during the past year included: design improvements of the inboard shield developed for the TIBER concept, scoping studies of a variety of tritium breeding blanket options, development of necessary design guidelines and evaluation criteria for the blanket options, further safety considerations related to nuclear components and issues regarding structural materials for an ITER device. 44 refs., 31 figs., 29 tabs.

  10. Energy iteration model research of DCM Buck converter with multilevel pulse train technique

    Science.gov (United States)

    Qin, Ming; Li, Xiang

    2017-08-01

    According as the essence of switching converter is the nature of energy, the energy iteration model of the Multilevel Pulse Train (MPT) technique is studied in this paper. The energy iteration model of DCM Buck converter with MPT technique can reflect the control law and excellent transient performance of the MPT technique. The iteration relation of energy transfer in switching converter is discussed. The structure and operation principle of DCM Buck converter with MPT technique is introduced and the energy iteration model of this converter is set up. The energy tracks of MPT-control Buck converter and PT converter is researched and compared to show that the ratio of steady-state control pulse satisfies the expectation for the MPT technique and the MPT-controlled switching converter has much lower output voltage ripple than the PT converter.

  11. A New Iterative Scheme of Modified Mann Iteration in Banach Space

    Directory of Open Access Journals (Sweden)

    Jinzuo Chen

    2014-01-01

    Full Text Available We introduce the modified iterations of Mann's type for nonexpansive mappings and asymptotically nonexpansive mappings to have the strong convergence in a uniformly convex Banach space. We study approximation of common fixed point of asymptotically nonexpansive mappings in Banach space by using a new iterative scheme. Applications to the accretive operators are also included.

  12. Picard iteration converges faster than Mann iteration for a class of quasi-contractive operators

    Directory of Open Access Journals (Sweden)

    Vasile Berinde

    2004-06-01

    Full Text Available In the class of quasi-contractive operators satisfying Zamfirescu's conditions, the most used fixed point iterative methods, that is, the Picard, Mann, and Ishikawa iterations, are all known to be convergent to the unique fixed point. In this paper, the comparison of the first two methods with respect to their convergence rate is obtained.

  13. Study of neutron spectrometers for ITER

    Energy Technology Data Exchange (ETDEWEB)

    Kaellne, Jan

    2005-11-15

    A review is presented of the developments in the field of neutron emission spectrometry (NES) which is of relevance for identifying the role of NES diagnostics on ITER and selecting suitable instrumentation. Neutron spectrometers will be part of the ITER neutron diagnostic complement and this study makes a special effort to examine which performance characteristics the spectrometers should possess to provide the best burning plasma diagnostic information together with neutron cameras and neutron yield monitors. The performance of NES diagnostics is coupled to how much interface space can be provided which has lead to an interest to find compact instruments and their NES capabilities. This study assesses all known spectrometer types of potential interest for ITER and makes a ranking of their performance (as demonstrated or projected), which, in turn, are compared with ITER measurement requirements as a reference; the ratio of diagnostic performance to interface cost for different spectrometers is also discussed for different spectrometer types. The overall result of the study is an assessment of which diagnostic functions neutron measurements can provide in burning plasma fusion experiments on ITER and the role that NES can play depending on the category of instrument installed. Of special note is the result that much higher quality diagnostic information can be obtained from neutron measurements with total yield monitors, profile flux cameras and spectrometers when the synergy in the data is considered in the analysis and interpretation.

  14. Status of ITER neutron diagnostic development

    Science.gov (United States)

    Krasilnikov, A. V.; Sasao, M.; Kaschuck, Yu. A.; Nishitani, T.; Batistoni, P.; Zaveryaev, V. S.; Popovichev, S.; Iguchi, T.; Jarvis, O. N.; Källne, J.; Fiore, C. L.; Roquemore, A. L.; Heidbrink, W. W.; Fisher, R.; Gorini, G.; Prosvirin, D. V.; Tsutskikh, A. Yu.; Donné, A. J. H.; Costley, A. E.; Walker, C. I.

    2005-12-01

    Due to the high neutron yield and the large plasma size many ITER plasma parameters such as fusion power, power density, ion temperature, fast ion energy and their spatial distributions in the plasma core can be measured well by various neutron diagnostics. Neutron diagnostic systems under consideration and development for ITER include radial and vertical neutron cameras (RNC and VNC), internal and external neutron flux monitors (NFMs), neutron activation systems and neutron spectrometers. The two-dimensional neutron source strength and spectral measurements can be provided by the combined RNC and VNC. The NFMs need to meet the ITER requirement of time-resolved measurements of the neutron source strength and can provide the signals necessary for real-time control of the ITER fusion power. Compact and high throughput neutron spectrometers are under development. A concept for the absolute calibration of neutron diagnostic systems is proposed. The development, testing in existing experiments and the engineering integration of all neutron diagnostic systems into ITER are in progress and the main results are presented.

  15. Dark Matter Candidates

    Energy Technology Data Exchange (ETDEWEB)

    Baltz, E.

    2004-12-03

    It is now widely accepted that most of mass-energy in the universe is unobserved except by its gravitational effects. Baryons make only about 4% of the total, with ''dark matter'' making up about 23% and the ''dark energy'' responsible for the accelerated expansion of the universe making up the remainder. We focus on the dark matter, which is the primary constituent of galaxies. We outline the observed properties of this material, enumerating some candidates covering 90 orders of magnitude in mass. Finally, we argue that the weak scale (100 GeV) is relevant to new physics, including the dark matter problem.

  16. Design and integration of lower ports for ITER diagnostic systems

    Energy Technology Data Exchange (ETDEWEB)

    Casal, Natalia, E-mail: Natalia.casal@iter.org [ITER Organization, Route de Vinon-sur-Verdon – CS 90 046 – 13067 St Paul Lez Durance Cedex (France); Bertalot, Luciano; Cheng, Hao; Drevon, Jean Marc; Duckworth, Philip; Giacomin, Thibaud; Guirao, Julio; Iglesias, Silvia [ITER Organization, Route de Vinon-sur-Verdon – CS 90 046 – 13067 St Paul Lez Durance Cedex (France); Kochergin, Mikhail [IOFFE Institute, Saint Petersburg (Russian Federation); Martin, Alex [ITER Organization, Route de Vinon-sur-Verdon – CS 90 046 – 13067 St Paul Lez Durance Cedex (France); McCarron, Eddie [Oxford Technologies Ltd., Abingdon (United Kingdom); Mokeev, Alexander [Russian Federation Domestic Agency, Moscow (Russian Federation); Mota, Fernando [CIEMAT, Madrid (Spain); Penot, Christophe; Portales, Mickael [ITER Organization, Route de Vinon-sur-Verdon – CS 90 046 – 13067 St Paul Lez Durance Cedex (France); Kitazawa, Sin-iti [Japanese Domestic Agency, Naka (Japan); Sky, Jack [Oxford Technologies Ltd., Abingdon (United Kingdom); Suarez, Alejandro; Udintsev, Victor; Utin, Yuri [ITER Organization, Route de Vinon-sur-Verdon – CS 90 046 – 13067 St Paul Lez Durance Cedex (France); and others

    2015-10-15

    Highlights: • Lower port structures are in its conceptual design phase. • Electromagnetic and seismic loads, will dominate all other mechanical loads. • Design allows diagnostics support, neutron shielding while and signals transmission. • Installation and maintenance operations are fully remote handling compatible. - Abstract: All around the ITER vacuum vessel, forty-four ports will provide access to the vacuum vessel for remote handling operations, diagnostic systems, heating, and vacuum systems: 18 upper ports, 17 equatorial ports, and 9 lower ports. Among the lower ports, three of them will be used for the remote handling installation of the ITER divertor. Once the divertor is in place, these ports will host various diagnostic systems mounted in the so-called diagnostic racks. The diagnostic racks must allow the support and cooling of the diagnostics, extraction of the required diagnostic signals, and providing access and maintainability while minimizing the leakage of radiation toward the back of the port where the humans are allowed to enter. A fully integrated inner rack, carrying the near plasma diagnostic components, will be an stainless steel structure, 4.2 m long, with a maximum weight of 10 t. This structure brings water for cooling and baking at maximum temperature of 240 °C and provides connection with gas, vacuum and electric services. Additional racks (placed away from plasma and not requiring cooling) may be required for the support of some particular diagnostic components. The diagnostics racks and its associated ex vessel structures, which are in its conceptual design phase, are being designed to survive the lifetime of ITER of 20 years. This paper presents the current state of development including interfaces, diagnostic integration, operation and maintenance, shielding requirements, remote handling, loads cases and discussion of the main challenges coming from the severe environment and engineering requirements.

  17. Progress with the ITER project activity in Russia

    Science.gov (United States)

    Krasilnikov, A. V.; Abdyuhanov, I. M.; Aleksandrov, E. V.; Alekseev, A. G.; Amosov, V. N.; Antonov, N. V.; Arkhipov, N. I.; Burdakov, A. V.; Chugunov, I. N.; Denisov, G. G.; Gervash, A. A.; Ivantsivskiy, M. V.; Kaschuk, Yu. A.; Khomyakov, S. E.; Krasilnikov, V. A.; Kupriyanov, I. B.; Kuzmin, E. G.; Kuznetsov, V. E.; Lelekhov, S. A.; Leshukov, A. Yu.; Litvak, A. G.; Makhankov, A. N.; Mazul, I. V.; Mokeev, A. N.; Mukhin, E. E.; Petrov, A. A.; Petrov, M. P.; Petrov, S. Ya.; Petrov, V. G.; Rodin, I. Yu.; Romannikov, A. N.; Rumyantsev, Yu. N.; Safronov, V. M.; Savrukhin, P. V.; Tronza, V. I.; Tugarinov, S. N.; Ustinov, A. L.; Vershkov, V. A.; Vdovin, V. L.; Vysotsky, V. S.; Zernov, S. N.; Zhitlukhin, A. M.; Zvonkov, A. V.

    2015-10-01

    Due to the development of the ITER project, the requirements of the technical parameters of the ITER systems were more precisely and practically determined to be at higher levels. The essential increase of the ITER system characteristics happened recently. A number of prototypes were manufactured and tests were carried out. The results of the development and manufacture of 25 ITER systems, subject to the Russian Federation's obligations in the ITER project, are described.

  18. Structure, magnetic susceptibility, and specific heat of the spin-orbital-liquid candidate FeS c2S4 : Influence of Fe off-stoichiometry

    Science.gov (United States)

    Tsurkan, V.; Prodan, L.; Felea, V.; Filippova, I.; Kravtsov, V.; Günther, A.; Widmann, S.; Krug von Nidda, H.-A.; Deisenhofer, J.; Loidl, A.

    2017-08-01

    We report structure, susceptibility, and specific heat studies of stoichiometric and off-stoichiometric poly- and single crystals of the A -site spinel compound FeS c2S4 . In stoichiometric samples, no long-range magnetic order is found down to 1.8 K. The magnetic susceptibility of these samples is field independent in the temperature range 10-400 K and does not show irreversible effects at low temperatures. In contrast, the magnetic susceptibility of samples with iron excess shows substantial field dependence at high temperatures and manifests a pronounced magnetic irreversibility at low temperatures with a difference between zero-field cooled (ZFC) and field cooled (FC) susceptibilities and a maximum at 10 K, reminiscent of a magnetic transition. Single-crystal x-ray diffraction of the stoichiometric samples revealed a single phase spinel structure without site inversion. In single crystalline samples with Fe excess, in addition to the main spinel phase, a second ordered single-crystal phase was detected with the diffraction pattern of a vacancy-ordered superstructure of iron sulfide, close to the 5C polytype F e9S10 . Specific heat studies reveal a broad anomaly, which evolves below 20 K in both stoichiometric and off-stoichiometric crystals. We show that the low-temperature specific heat can be well described by considering the low-lying spin-orbital electronic levels of F e2 + ions. Our results demonstrate significant influence of excess Fe ions on intrinsic magnetic behavior of FeS c2S4 and provide support for the spin-orbital liquid scenario proposed in earlier studies for the stoichiometric compound.

  19. Solution structure of a Plasmodium falciparum AMA-1/MSP 1 chimeric protein vaccine candidate (PfCP-2.9 for malaria

    Directory of Open Access Journals (Sweden)

    Jin Changwen

    2010-03-01

    Full Text Available Abstract Background The Plasmodium falciparum chimeric protein PfCP-2.9 is a promising asexual-stage malaria vaccine evaluated in clinical trials. This chimeric protein consists of two cysteine-rich domains: domain III of the apical membrane antigen 1 (AMA-1 [III] and the C-terminal region of the merozoite surface protein 1 (MSP1-19. It has been reported that the fusion of these two antigens enhanced their immunogenicity and antibody-mediated inhibition of parasite growth in vitro. Methods The 15N-labeled and 13C/15N-labeled PfCP-2.9 was produced in Pichia pastoris for nuclear magnetic resonance (NMR structure analysis. The chemical shift assignments of PfCP-2.9 were compared with those previously reported for the individual domains (i.e., PfAMA-1(III or PfMSP 1-19. The two-dimensional spectra and transverse relaxation rates (R2 of the PfMSP1-19 alone were compared with that of the PfCP-2.9. Results Confident backbone assignments were obtained for 122 out of 241 residues of PfCP-2.9. The assigned residues in PfCP-2.9 were very similar to those previously reported for the individual domains. The conformation of the PfMSP1-19 in different constructs is essentially the same. Comparison of transverse relaxation rates (R2 strongly suggests no weak interaction between the domains. Conclusions These data indicate that the fusion of AMA-1(III and MSP1-19 as chimeric protein did not change their structures, supporting the use of the chimeric protein as a potential malaria vaccine.

  20. Cyclic game dynamics driven by iterated reasoning

    CERN Document Server

    Frey, Seth

    2012-01-01

    Recent theories from complexity science argue that complex dynamics are ubiquitous in social and economic systems. These claims emerge from the analysis of individually simple agents whose collective behavior is surprisingly complicated. However, game theorists have argued that iterated reasoning-our ability to think through what you think I think you think-will prevent complex dynamics and facilitate convergence to classic equilibria. We report stable and efficient periodic behavior in human groups playing the Mod Game, a multi-player game similar to Rock-Paper-Scissors. The game rewards subjects for thinking exactly one step ahead of others in their group. Groups that play this game exhibit cycles that are inconsistent with any fixed-point equilibrium concept. These cycles are driven by a "hopping" behavior that can only be explained by iterated reasoning. If iterated reasoning can be complicit in complex dynamics, then game cycles and chaos may realistically be driving fluctuations in real-world social and...

  1. Iterative Reconstruction of Coded Source Neutron Radiographs

    Energy Technology Data Exchange (ETDEWEB)

    Santos-Villalobos, Hector J [ORNL; Bingham, Philip R [ORNL; Gregor, Jens [University of Tennessee, Knoxville (UTK)

    2013-01-01

    Use of a coded source facilitates high-resolution neutron imaging through magnifications but requires that the radiographic data be deconvolved. A comparison of direct deconvolution with two different iterative algorithms has been performed. One iterative algorithm is based on a maximum likelihood estimation (MLE)-like framework and the second is based on a geometric model of the neutron beam within a least squares formulation of the inverse imaging problem. Simulated data for both uniform and Gaussian shaped source distributions was used for testing to understand the impact of non-uniformities present in neutron beam distributions on the reconstructed images. Results indicate that the model based reconstruction method will match resolution and improve on contrast over convolution methods in the presence of non-uniform sources. Additionally, the model based iterative algorithm provides direct calculation of quantitative transmission values while the convolution based methods must be normalized base on known values.

  2. Advances in iterative methods for nonlinear equations

    CERN Document Server

    Busquier, Sonia

    2016-01-01

    This book focuses on the approximation of nonlinear equations using iterative methods. Nine contributions are presented on the construction and analysis of these methods, the coverage encompassing convergence, efficiency, robustness, dynamics, and applications. Many problems are stated in the form of nonlinear equations, using mathematical modeling. In particular, a wide range of problems in Applied Mathematics and in Engineering can be solved by finding the solutions to these equations. The book reveals the importance of studying convergence aspects in iterative methods and shows that selection of the most efficient and robust iterative method for a given problem is crucial to guaranteeing a good approximation. A number of sample criteria for selecting the optimal method are presented, including those regarding the order of convergence, the computational cost, and the stability, including the dynamics. This book will appeal to researchers whose field of interest is related to nonlinear problems and equations...

  3. SPARSE ELECTROMAGNETIC IMAGING USING NONLINEAR LANDWEBER ITERATIONS

    KAUST Repository

    Desmal, Abdulla

    2015-07-29

    A scheme for efficiently solving the nonlinear electromagnetic inverse scattering problem on sparse investigation domains is described. The proposed scheme reconstructs the (complex) dielectric permittivity of an investigation domain from fields measured away from the domain itself. Least-squares data misfit between the computed scattered fields, which are expressed as a nonlinear function of the permittivity, and the measured fields is constrained by the L0/L1-norm of the solution. The resulting minimization problem is solved using nonlinear Landweber iterations, where at each iteration a thresholding function is applied to enforce the sparseness-promoting L0/L1-norm constraint. The thresholded nonlinear Landweber iterations are applied to several two-dimensional problems, where the ``measured\\'\\' fields are synthetically generated or obtained from actual experiments. These numerical experiments demonstrate the accuracy, efficiency, and applicability of the proposed scheme in reconstructing sparse profiles with high permittivity values.

  4. Iterative Contracts as Proactive Law Instruments

    DEFF Research Database (Denmark)

    Henschel, René Franz

    2012-01-01

    The purpose of this article is to analyse the use of proactive law in contracts illustrated by the use of a particular type of contract within the IT industry, the so-called iterative contract. This type of contract has its root in a special software development process called iterative....... This software development process has driven the need for a new contract design that supports the product life cycle better than the traditional contracts. As will be shown in the analysis, the iterative contracts represent important legal innovation and can be categorized as a proactive law instrument that has...... the potential to create more business success. However, empirical research still needs to be done in order to confirm that these types of contracts are better at securing business success than traditional contract forms....

  5. The ITER in-vessel system

    Energy Technology Data Exchange (ETDEWEB)

    Lousteau, D.C.

    1994-09-01

    The overall programmatic objective, as defined in the ITER Engineering Design Activities (EDA) Agreement, is to demonstrate the scientific and technological feasibility of fusion energy for peaceful purposes. The ITER EDA Phase, due to last until July 1998, will encompass the design of the device and its auxiliary systems and facilities, including the preparation of engineering drawings. The EDA also incorporates validating research and development (R&D) work, including the development and testing of key components. The purpose of this paper is to review the status of the design, as it has been developed so far, emphasizing the design and integration of those components contained within the vacuum vessel of the ITER device. The components included in the in-vessel systems are divertor and first wall; blanket and shield; plasma heating, fueling, and vacuum pumping equipment; and remote handling equipment.

  6. Burning plasmas in ITER for energy source

    Energy Technology Data Exchange (ETDEWEB)

    Inoue, Nobuyuki [Atomic Energy Commission, Tokyo (Japan)

    2002-10-01

    Fusion research and development has two aspects. One is an academic research on science and technology, i.e., discovery and understanding of unexpected phenomena and, development of innovative technology, respectively. The other is energy source development to realize fusion as a viable energy future. Fusion research has been made remarkable progress in the past several decades, and ITER will soon realize burning plasma that is essential for both academic research and energy development. With ITER, scientific research on unknown phenomena such as self-organization of the plasma in burning state will become possible and it contributes to create a variety of academic outcome. Fusion researchers will have a responsibility to generate actual energy, and electricity generation immediately after the success of burning plasma control experiment in ITER is the next important step that has to be discussed seriously. (author)

  7. Re-starting an Arnoldi iteration

    Energy Technology Data Exchange (ETDEWEB)

    Lehoucq, R.B. [Argonne National Lab., IL (United States)

    1996-12-31

    The Arnoldi iteration is an efficient procedure for approximating a subset of the eigensystem of a large sparse n x n matrix A. The iteration produces a partial orthogonal reduction of A into an upper Hessenberg matrix H{sub m} of order m. The eigenvalues of this small matrix H{sub m} are used to approximate a subset of the eigenvalues of the large matrix A. The eigenvalues of H{sub m} improve as estimates to those of A as m increases. Unfortunately, so does the cost and storage of the reduction. The idea of re-starting the Arnoldi iteration is motivated by the prohibitive cost associated with building a large factorization.

  8. Screening of promising chemotherapeutic candidates against human adult T-cell leukemia/lymphoma from plants: active principles from Physalis pruinosa and structure-activity relationships with withanolides.

    Science.gov (United States)

    Nakano, Daisuke; Ishitsuka, Kenji; Hatsuse, Takahiro; Tsuchihashi, Ryota; Okawa, Masafumi; Okabe, Hikaru; Tamura, Kazuo; Kinjo, Junei

    2011-07-01

    Adult T-cell leukemia/lymphoma (ATL) is a peripheral T-cell malignancy caused by human T-cell lymphotropic virus type I (HTLV-1). Clinical manifestations of ATL range from smoldering to chronic, lymphoma and acute subtypes. Patients with acute and lymphoma-type ATL require therapeutic intervention. Conventional chemotherapeutic regimens used against other malignant lymphoma have been administered to ATL patients, but the therapeutic outcomes of acute and lymphoma-type ATL remain very poor. In this study, 214 extracts from 162 plants belonging to 65 families were screened for the purpose of elucidating the anti-proliferative effect against HTLV-1-infected T-cell lines. Extracts from aerial parts of Physalis pruinosa showed potent inhibitory effect. We isolated five withanolides from the extracts by activity-guided fractionation and examined the structure-activity relationships. The presence of a 5β,6β-epoxy function is suggested to be essential for the activity, and the most active principle showed selective toxicity to HTLV-1-infected T-cell lines.

  9. Highly charged W+13, Ir+16, and Pt+17 ions as promising optical clock candidates for probing variations of the fine-structure constant

    Science.gov (United States)

    Nandy, D. K.; Sahoo, B. K.

    2016-09-01

    Transitions among the first three low-lying states in the highly charged W+13, Ir+16, and Pt+17 ions are found to be strongly forbidden with wavelengths in the optical regime. By determining their energy levels, lifetimes, and other spectroscopic properties that are decisive quantities for estimating dominant systematics due to stray electromagnetic interactions in an experiment, we demonstrate that it can be possible to measure frequencies of the lowest forbidden transitions below a 10-19 precision level in the above ions, and hence, they seem to be suitable for frequency standards. We employ a sophisticated relativistic coupled cluster method to carry out calculations of these properties of the above states involving 4 f - and 5 s -core orbitals. We also found, by estimating their relativistic sensitivity coefficients, that these clock transitions can be highly sensitive to the tiny drift in the fine-structure constant αe. Consequently, a clock based on one of these ions, particularly Pt+17, could be used for corroborating the hypothesis of temporal and spatial variation in αe.

  10. Molecular interaction studies of green tea catechins as multitarget drug candidates for the treatment of Parkinson's disease: computational and structural insights.

    Science.gov (United States)

    Azam, Faizul; Mohamed, Najah; Alhussen, Fatma

    2015-01-01

    Green tea catechins have extensively been studied for their imminent role in reducing the risk of various neurodegenerative diseases such as Parkinson's disease (PD). Understanding the molecular interaction of these compounds with various anti-Parkinsonian drug targets is of interest. The present study is intended to explore binding modes of catechins with molecular targets having potential role in PD. Lamarckian genetic algorithm methodology was adopted for molecular docking simulations employing AutoDock 4.2 program. Toxicity potential and molecular properties responsible for good pharmacokinetic profile were calculated by Osiris property explorer and Molinspiration online toolkit, respectively. A strong correlation coefficient (r(2) = 0.893) was obtained between experimentally reported and docking predicted activities of native co-crystallized ligands of the 18 target receptors used in current study. Analysis of docked conformations revealed monoamine oxidase-B as most promising, while N-methyl-D-aspartate receptor was recognized as the least favorable target for catechins. Benzopyran skeleton with a phenyl group substituted at the 2-position and a hydroxyl (or ester) function at the 3-position has been identified as common structural requirements at majority of the targets. The present findings suggest that epigallocatechin gallate is the most promising lead to be developed as multitarget drug for the design and development of novel anti-Parkinsonian agents.

  11. Correction of spin diffusion during iterative automated NOE assignment.

    Science.gov (United States)

    Linge, Jens P; Habeck, Michael; Rieping, Wolfgang; Nilges, Michael

    2004-04-01

    Indirect magnetization transfer increases the observed nuclear Overhauser enhancement (NOE) between two protons in many cases, leading to an underestimation of target distances. Wider distance bounds are necessary to account for this error. However, this leads to a loss of information and may reduce the quality of the structures generated from the inter-proton distances. Although several methods for spin diffusion correction have been published, they are often not employed to derive distance restraints. This prompted us to write a user-friendly and CPU-efficient method to correct for spin diffusion that is fully integrated in our program ambiguous restraints for iterative assignment (ARIA). ARIA thus allows automated iterative NOE assignment and structure calculation with spin diffusion corrected distances. The method relies on numerical integration of the coupled differential equations which govern relaxation by matrix squaring and sparse matrix techniques. We derive a correction factor for the distance restraints from calculated NOE volumes and inter-proton distances. To evaluate the impact of our spin diffusion correction, we tested the new calibration process extensively with data from the Pleckstrin homology (PH) domain of Mus musculus beta-spectrin. By comparing structures refined with and without spin diffusion correction, we show that spin diffusion corrected distance restraints give rise to structures of higher quality (notably fewer NOE violations and a more regular Ramachandran map). Furthermore, spin diffusion correction permits the use of tighter error bounds which improves the distinction between signal and noise in an automated NOE assignment scheme.

  12. Jellyfish Galaxy Candidates at Low Redshift

    Science.gov (United States)

    Poggianti, B. M.; Fasano, G.; Omizzolo, A.; Gullieuszik, M.; Bettoni, D.; Moretti, A.; Paccagnella, A.; Jaffé, Y. L.; Vulcani, B.; Fritz, J.; Couch, W.; D'Onofrio, M.

    2016-03-01

    Galaxies that are being stripped of their gas can sometimes be recognized from their optical appearance. Extreme examples of stripped galaxies are the so-called “jellyfish galaxies” that exhibit tentacles of debris material with a characteristic jellyfish morphology. We have conducted the first systematic search for galaxies that are being stripped of their gas at low-z (z = 0.04-0.07) in different environments, selecting galaxies with varying degrees of morphological evidence for stripping. We have visually inspected B- and V-band images and identified 344 candidates in 71 galaxy clusters of the OMEGAWINGS+WINGS sample and 75 candidates in groups and lower mass structures in the PM2GC sample. We present the atlas of stripping candidates and a first analysis of their environment and their basic properties, such as morphologies, star formation rates and galaxy stellar masses. Candidates are found in all clusters and at all clustercentric radii, and their number does not correlate with the cluster velocity dispersion σ or X-ray luminosity LX. Interestingly, convincing cases of candidates are also found in groups and lower mass halos (1011-1014M⊙), although the physical mechanism at work needs to be securely identified. All the candidates are disky, have stellar masses ranging from log M/M⊙ 11.5 and the majority of them form stars at a rate that is on average a factor of 2 higher (2.5σ) compared to non-stripped galaxies of similar mass. The few post-starburst and passive candidates have weak stripping evidence. We conclude that disturbed morphologies suggestive of stripping phenomena are ubiquitous in clusters and could be present even in groups and low mass halos. Further studies will reveal the physics of the gas stripping and clarify the mechanisms at work.

  13. JELLYFISH GALAXY CANDIDATES AT LOW REDSHIFT

    Energy Technology Data Exchange (ETDEWEB)

    Poggianti, B. M.; Fasano, G.; Omizzolo, A.; Gullieuszik, M.; Bettoni, D.; Paccagnella, A. [INAF-Astronomical Observatory of Padova (Italy); Moretti, A.; D’Onofrio, M. [Physics and Astronomy Department, University of Padova (Italy); Jaffé, Y. L. [Department of Astronomy, Universidad de Concepción, Concepción (Chile); Vulcani, B. [Kavli Institute for the Physics and Mathematics of the universe (WPI), The University of Tokyo Institutes for Advanced Study (UTIAS), the University of Tokyo, Kashiwa, 277-8582 (Japan); Fritz, J. [Centro de Radioastronomía y Astrofísica, CRyA, UNAM, Michoacán (Mexico); Couch, W. [Australian Astronomical Observatory, North Ryde, NSW 1670 (Australia)

    2016-03-15

    Galaxies that are being stripped of their gas can sometimes be recognized from their optical appearance. Extreme examples of stripped galaxies are the so-called “jellyfish galaxies” that exhibit tentacles of debris material with a characteristic jellyfish morphology. We have conducted the first systematic search for galaxies that are being stripped of their gas at low-z (z = 0.04−0.07) in different environments, selecting galaxies with varying degrees of morphological evidence for stripping. We have visually inspected B- and V-band images and identified 344 candidates in 71 galaxy clusters of the OMEGAWINGS+WINGS sample and 75 candidates in groups and lower mass structures in the PM2GC sample. We present the atlas of stripping candidates and a first analysis of their environment and their basic properties, such as morphologies, star formation rates and galaxy stellar masses. Candidates are found in all clusters and at all clustercentric radii, and their number does not correlate with the cluster velocity dispersion σ or X-ray luminosity L{sub X}. Interestingly, convincing cases of candidates are also found in groups and lower mass halos (10{sup 11}−10{sup 14}M{sub ⊙}), although the physical mechanism at work needs to be securely identified. All the candidates are disky, have stellar masses ranging from log M/M{sub ⊙} < 9 to > 11.5 and the majority of them form stars at a rate that is on average a factor of 2 higher (2.5σ) compared to non-stripped galaxies of similar mass. The few post-starburst and passive candidates have weak stripping evidence. We conclude that disturbed morphologies suggestive of stripping phenomena are ubiquitous in clusters and could be present even in groups and low mass halos. Further studies will reveal the physics of the gas stripping and clarify the mechanisms at work.

  14. Iterative quantum algorithm for distributed clock synchronization

    Institute of Scientific and Technical Information of China (English)

    Wang Hong-Fu; Zhang Shou

    2012-01-01

    Clock synchronization is a well-studied problem with many practical and scientific applications.We propose an arbitrary accuracy iterative quantum algorithm for distributed clock synchronization using only three qubits.The n bits of the time difference △ between two spatially separated clocks can be deterministically extracted by communicating only O(n) messages and executing the quantum iteration process n times based on the classical feedback and measurement operations.Finally,we also give the algorithm using only two qubits and discuss the success probability of the algorithm.

  15. Rational Verification in Iterated Electric Boolean Games

    Directory of Open Access Journals (Sweden)

    Youssouf Oualhadj

    2016-07-01

    Full Text Available Electric boolean games are compact representations of games where the players have qualitative objectives described by LTL formulae and have limited resources. We study the complexity of several decision problems related to the analysis of rationality in electric boolean games with LTL objectives. In particular, we report that the problem of deciding whether a profile is a Nash equilibrium in an iterated electric boolean game is no harder than in iterated boolean games without resource bounds. We show that it is a PSPACE-complete problem. As a corollary, we obtain that both rational elimination and rational construction of Nash equilibria by a supervising authority are PSPACE-complete problems.

  16. Iterative solution of large linear systems

    CERN Document Server

    Young, David M

    2003-01-01

    This self-contained treatment offers a systematic development of the theory of iterative methods. Its focal point resides in an analysis of the convergence properties of the successive overrelaxation (SOR) method, as applied to a linear system with a consistently ordered matrix. The text explores the convergence properties of the SOR method and related techniques in terms of the spectral radii of the associated matrices as well as in terms of certain matrix norms. Contents include a review of matrix theory and general properties of iterative methods; SOR method and stationary modified SOR meth

  17. Precise fixpoint computation through strategy iteration

    DEFF Research Database (Denmark)

    Gawlitza, Thomas; Seidl, Helmut

    2007-01-01

    We present a practical algorithm for computing least solutions of systems of equations over the integers with addition, multiplication with positive constants, maximum and minimum. The algorithm is based on strategy iteration. Its run-time (w.r.t. the uniform cost measure) is independent of the s......We present a practical algorithm for computing least solutions of systems of equations over the integers with addition, multiplication with positive constants, maximum and minimum. The algorithm is based on strategy iteration. Its run-time (w.r.t. the uniform cost measure) is independent...

  18. Beyond ITER: Neutral beams for DEMO

    CERN Document Server

    McAdams, R

    2013-01-01

    In the development of magnetically confined fusion as an economically sustainable power source, ITER is currently under construction. Beyond ITER is the DEMO programme in which the physics and engineering aspects of a future fusion power plant will be demonstrated. DEMO will produce net electrical power. The DEMO programme will be outlined and the role of neutral beams for heating and current drive will be described. In particular, the importance of the efficiency of neutral beam systems in terms of injected neutral beam power compared to wallplug power will be discussed. Options for improving this efficiency including advanced neutralisers and energy recovery are discussed.

  19. Iterative Contracts as Proactive Law Instruments

    DEFF Research Database (Denmark)

    Henschel, René Franz

    2012-01-01

    and incremental software development. In contrast to traditional IT project methodologies, where the product development takes place in a sequential design process, the iterative process is characterized by the so_ ware being developed through a series of repeated cycles in smaller portions at a time....... This software development process has driven the need for a new contract design that supports the product life cycle better than the traditional contracts. As will be shown in the analysis, the iterative contracts represent important legal innovation and can be categorized as a proactive law instrument that has...

  20. Efficient iterative technique for designing bragg gratings

    DEFF Research Database (Denmark)

    Plougmann, Nikolai; Kristensen, Martin

    2004-01-01

    We present a new iterative method for designing Bragg gratings based on the Levenberg-Marquardt method of minimizing a chi-squared merit function. It is effective for designing both weak and strong gratings and is particularly well suited for unchirped gratings.......We present a new iterative method for designing Bragg gratings based on the Levenberg-Marquardt method of minimizing a chi-squared merit function. It is effective for designing both weak and strong gratings and is particularly well suited for unchirped gratings....

  1. Fatigue tests on the ITER PF jacket

    Science.gov (United States)

    Qin, Jinggang; Weiss, Klaus-Peter; Wu, Yu; Wu, Zhixiong; Li, Laifeng; Liu, Sheng

    2012-10-01

    This paper focuses on fatigue tests on the ITER Poloidal Field (PF) jacket made of 316L stainless steel material. During manufacture, the conductor will be compacted and spooled after cable insertion. Therefore, sample jackets were prepared under compaction, bending and straightening in order to simulate the status of PF conductor during manufacturing and winding. The fatigue properties of materials were measured at T fatigue crack growth rate (FCGR). The testing results show that the present Chinese PF jacket has good fatigue properties, which conclude that the results are accordant with the requirements of ITER.

  2. Retractable tube design issues in ITER CXRS UPP no. 3

    Energy Technology Data Exchange (ETDEWEB)

    Baross, T., E-mail: baross.teteny@wigner.mta.hu [WIGNER RCP, RMKI, PO Box 91, H-1521 Budapest (Hungary); Biel, W. [Institut für Energieforschung – Plasmaphysik, Forschungszentrum Jülich Gmbh, Association EURATOM-FZJ, Member of Trilateral Euregio Cluster, 52425 Jülich (Germany); Krejczinger, A. [WIGNER RCP, RMKI, PO Box 91, H-1521 Budapest (Hungary); Krasikov, Yu.; Panin, A. [Institut für Energieforschung – Plasmaphysik, Forschungszentrum Jülich Gmbh, Association EURATOM-FZJ, Member of Trilateral Euregio Cluster, 52425 Jülich (Germany)

    2013-10-15

    Highlights: ► The retractable tube is located in the upper port plug no. 3 of ITER core charge exchange recombination spectroscopy (cCXRS) that carries the cleaning system of the first mirror. ► Various manufacturing methods were investigated for the proper layout of the tube cooling structure. ► The tube support boundary conditions were examined. ► A flexible compensator element was developed between the floating and structural flange of the tube. -- Abstract: The retractable tube is located in the upper port plug no. 3 of ITER core charge exchange recombination spectroscopy (cCXRS), where it is surrounded by a set of mirrors, diagnostic shielding module (DSM), outer shell, cleaning device and shutter. Accordingly to the recent port plug concept the tube is an optional unit that carries the cleaning system of the first mirror. The cleaning device shall be a compact instrument at the tube head that influences the tube diameter primarily. Independently of the cleaning device the tube cooling channels and its proper support concept has to be developed. Various manufacturing methods are investigated for the proper layout of the tube cooling structure. They are the gun-drilled deep holes, the solid state bonded sheets forming cooling channels between the welded layers, ‘tube-in-tube’ approach. Most of them were analyzed in view of their thermal conditions. The tube support system design is a complex task, that has to take into account several boundary conditions and limitations. The tube must be compatible with the assumed ITER generic installation procedure, withstand the electromagnetic (EM) and thermal loads. Furthermore, the tube has to be exchanged several times during its lifetime. The paper summarizes the tube cooling layout possibilities and the assumptions on its support concepts.

  3. Iterative Feedback Tuning in Fuzzy Control Systems. Theory and Applications

    Directory of Open Access Journals (Sweden)

    Stefan Preitl

    2006-07-01

    Full Text Available The paper deals with both theoretical and application aspects concerningIterative Feedback Tuning (IFT algorithms in the design of a class of fuzzy controlsystems employing Mamdani-type PI-fuzzy controllers. The presentation is focused on twodegree-of-freedom fuzzy control system structures resulting in one design method. Thestability analysis approach based on Popov’s hyperstability theory solves the convergenceproblems associated to IFT algorithms. The suggested design method is validated by realtimeexperimental results for a fuzzy controlled nonlinear DC drive-type laboratoryequipment.

  4. Estimation of carbon fibre composites as ITER divertor armour

    Science.gov (United States)

    Pestchanyi, S.; Safronov, V.; Landman, I.

    2004-08-01

    Exposure of the carbon fibre composites (CFC) NB31 and NS31 by multiple plasma pulses has been performed at the plasma guns MK-200UG and QSPA. Numerical simulation for the same CFCs under ITER type I ELM typical heat load has been carried out using the code PEGASUS-3D. Comparative analysis of the numerical and experimental results allowed understanding the erosion mechanism of CFC based on the simulation results. A modification of CFC structure has been proposed in order to decrease the armour erosion rate.

  5. New Iterative Learning Control Algorithms Based on Vector Plots Analysis1)

    Institute of Scientific and Technical Information of China (English)

    XIESheng-Li; TIANSen-Ping; XIEZhen-Dong

    2004-01-01

    Based on vector plots analysis, this paper researches the geometric frame of iterativelearning control method. New structure of iterative learning algorithms is obtained by analyzingthe vector plots of some general algorithms. The structure of the new algorithm is different fromthose of the present algorithms. It is of faster convergence speed and higher accuracy. Simulationspresented here illustrate the effectiveness and advantage of the new algorithm.

  6. New drug candidates in tuberculosis treatment

    Directory of Open Access Journals (Sweden)

    Begüm Evranos Aksöz

    2014-12-01

    makes them quit the treatment. From these problems emerges the need for development of effective new drugs, with smaller duration of therapy, less side effects and without the problem of resistance. After a long period such as 40 years, a new drug molecule bedaquiline was approved in December 2012 by FDA while the drug was in phase II research. Bedaquiline will be used in multidrug resistant tuberculosis therapy. When the chemical structures of bedaquilline and other candidate drugs were examined, the structures such as diarylquinoline, oxazolidinone, nitroimidazole, ethylenediamine drew attention. These common structures will be directive in designing new molecules. In this review, bedaquiline and other candidate drug molecules such as sutezolide, linezolide, PA-824, delamanide, rifapentine, gatifloxacin, moxifloxacin, BTZ-043, TBA-354, CPZEN-45, DC-159a, Q201, SQ-609, SQ-641 were mentioned.

  7. Validation of Helium Inlet Design for ITER Toroidal Field Coil

    CERN Document Server

    Boyer, C; Hamada, K; Foussat, A; Le Rest, M; Mitchell, N; Decool, P; Savary, F; Sgobba, S; Weiss, K-P

    2014-01-01

    The ITER organization has performed design and its validation tests on a helium inlet structure for the ITER Toroidal Field (TF) coil under collaboration with CERN, KIT, and CEA-Cadarache. Detailed structural analysis was performed in order to optimize the weld shape. A fatigue resistant design on the fillet weld between the shell covers and the jacket is an important point on the helium inlet structure. A weld filler material was selected based on tensile test at liquid helium temperature after Nb3Sn reaction heat treatment. To validate the design of the weld joint, fatigue tests at 7 K were performed using heat-treated butt weld samples. A pressure drop measurement of a helium inlet mock-up was performed by using nitrogen gas at room temperature in order to confirm uniform flow distribution and pressure drop characteristic. These tests have validated the helium inlet design. Based on the validation, Japanese and European Union domestic agencies, which have responsibilities of the TF coil procurement, are pr...

  8. AN ITERATIVE EQUATION ON THE UNIT CIRCLE

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    A functional equation of nonlinear iterates is discussed on the circle S1 for its continuous solutions and differentiable solutions. By lifting to R, the existence, uniqueness and stability of those solutions are obtained. Techniques of continuation are used to guarantee the preservation of continuity and differentiability in lifting.

  9. Precise fixpoint computation through strategy iteration

    DEFF Research Database (Denmark)

    Gawlitza, Thomas; Seidl, Helmut

    2007-01-01

    We present a practical algorithm for computing least solutions of systems of equations over the integers with addition, multiplication with positive constants, maximum and minimum. The algorithm is based on strategy iteration. Its run-time (w.r.t. the uniform cost measure) is independent...

  10. ITER Cryoplant Final Design and Construction

    Science.gov (United States)

    Monneret, E.; Benkheira, L.; Fauve, E.; Henry, D.; Voigt, T.; Badgujar, S.; Chang, H.-S.; Vincent, G.; Forgeas, A.; Navion-Maillot, N.

    2017-02-01

    The ITER Tokamak supraconducting magnets, thermal shields and cryopumps will require tremendous amount of cooling power. With an average need of 75 kW at 4.5 K and of 600 kW at 80 K, ITER requires a world class cryogenic complex. ITER then relies on a Cryoplant which consists in a cluster of systems dedicated to the management of all fluids required for the Tokamak operation. From storage and purification to liquefaction and refrigeration, the Cryoplant will supply to the distribution system, all fluids to be circulated in the Tokamak. It includes Liquid Helium Plants and Liquid Nitrogen Plants, which generate all of the refrigeration power, an 80 K helium loop capable to circulate large quantities of helium through thermal shields, and all the auxiliaries required for gas storage, purification, and onsite nitrogen production. From the conceptual phase, the design of the Cryoplant has evolved and is now nearing completion. This proceeding will present the final design of the Cryoplant and the organization for the construction phase. Also the latest status of the ITER Cryogenic System will be introduced.

  11. Asymptotic iteration approach to supersymmetric bistable potentials

    Institute of Scientific and Technical Information of China (English)

    H. Ciftci; O. ozer; P. Roy

    2012-01-01

    We examine quasi exactly solvable bistable potentials and their supersymmetric partners within the framework of the asymptotic iteration method (AIM).It is shown that the AIM produces excellent approximate spectra and that sometimes it is found to be more useful to use the partner potential for computation. We also discuss the direct application of the AIM to the Fokker-Planck equation.

  12. Neutronic analysis for bolometers in ITER

    Energy Technology Data Exchange (ETDEWEB)

    Suarez, A., E-mail: alejandro.suarez@iter.org [CIEMAT, Avda. Complutense 40, 28040 Madrid (Spain); Reichle, R.; Loughlin, M.; Polunovskiy, E.; Walsh, M. [ITER Organization, Route de Vinon sur Verdon, 13115, St. Paul lez Durance (France)

    2013-10-15

    Highlights: ► Radiation damage calculations for the bolometers in ITER. ► Redesign of the bolometric diagnostic in EPP01. ► New bolometer radiation damage values in EPP01 in the safe zone. -- Abstract: Neutronic considerations in ITER have such importance that they drive the design of many diagnostics and components of the machine, and bolometers are not an exception. Bolometer cameras will be installed on the vacuum vessel, viewing the plasma through the gaps between blanket modules, divertor, equatorial and upper port plugs. The ITER reference bolometer sensors are of a resistive type. For this study it is assumed that they are composed of a thin silicon nitride carrier film and platinum resistors disposed in a Wheatstone bridge configuration. Their assumed radiation hardness is 0.1 dpa. Neutronic calculations were performed with the Monte Carlo program MCNP5, the FENDL 2.1 nuclear data library and the latest B-lite ITER neutronic model with the appropriate modifications using the CAD to MCNP converter MCAM. A complete characterization of the neutron fluxes in all the bolometer locations and the calculation of neutron damage were performed. Values above the failure threshold damage were obtained for some of the bolometers, leading to a complete redesign of some parts of the bolometric system in order to extend its lifetime.

  13. Interpolation and Iteration for Nonlinear Filters

    CERN Document Server

    Chorin, Alexandre J

    2009-01-01

    We present a general form of the iteration and interpolation process used in implicit particle filters. Implicit filters are based on a pseudo-Gaussian representation of posterior densities, and are designed to focus the particle paths so as to reduce the number of particles needed in nonlinear data assimilation. Examples are given.

  14. Matched filter based iterative adaptive approach

    Science.gov (United States)

    Nepal, Ramesh; Zhang, Yan Rockee; Li, Zhengzheng; Blake, William

    2016-05-01

    Matched Filter sidelobes from diversified LPI waveform design and sensor resolution are two important considerations in radars and active sensors in general. Matched Filter sidelobes can potentially mask weaker targets, and low sensor resolution not only causes a high margin of error but also limits sensing in target-rich environment/ sector. The improvement in those factors, in part, concern with the transmitted waveform and consequently pulse compression techniques. An adaptive pulse compression algorithm is hence desired that can mitigate the aforementioned limitations. A new Matched Filter based Iterative Adaptive Approach, MF-IAA, as an extension to traditional Iterative Adaptive Approach, IAA, has been developed. MF-IAA takes its input as the Matched Filter output. The motivation here is to facilitate implementation of Iterative Adaptive Approach without disrupting the processing chain of traditional Matched Filter. Similar to IAA, MF-IAA is a user parameter free, iterative, weighted least square based spectral identification algorithm. This work focuses on the implementation of MF-IAA. The feasibility of MF-IAA is studied using a realistic airborne radar simulator as well as actual measured airborne radar data. The performance of MF-IAA is measured with different test waveforms, and different Signal-to-Noise (SNR) levels. In addition, Range-Doppler super-resolution using MF-IAA is investigated. Sidelobe reduction as well as super-resolution enhancement is validated. The robustness of MF-IAA with respect to different LPI waveforms and SNR levels is also demonstrated.

  15. Development of advanced inductive scenarios for ITER

    NARCIS (Netherlands)

    Luce, T. C.; Challis, C. D.; Ide, S.; Joffrin, E.; Kamada, Y.; Polizer, P. A.; Schweinzer, J.; Sips, A.C.C.; Stober, J.; Giruzzi, G.; Kessel, C. E.; Murakami, M.; Na, Y.-S.; Park, J. M.; Polevoi, A. R.; Budny, R. V.; Citrin, J.; Garcia, J.; Hayashi, N.; Hobirk, J.; Hudson, B. F.; Imbeaux, F.; Isayama, A.; McDonald, D. C.; Nakano, T.; Oyama, N.; Parail, V.V.; Petrie, T. W.; Petty, C. C.; Suzuki, T.; Wade, M. R.

    2014-01-01

    Since its inception in 2002, the International Tokamak Physics Activity topical group on Integrated Operational Scenarios (IOS) has coordinated experimental and modelling activity on the development of advanced inductive scenarios for applications in the ITER tokamak. The physics basis and the prosp

  16. Academic Training: The ITER project: technological challenges

    CERN Multimedia

    Françoise Benz

    2005-01-01

    2004-2005 ACADEMIC TRAINING PROGRAMME LECTURE SERIES 31 May, 1, 2, 3, June from 11:00 to 12:00 on 31 May and 2, 3, June. From 10:00 to 12:00 on 1 June - Main Auditorium, bldg. 500 The ITER project: technological challenges J. LISTER / CRPP-EPFL, Lausanne, CH and P. BRUZZONE / CRPP-EPFL, Zürich, CH The first lecture reminds us of the ITER challenges, presents hard engineering problems, typically due to mechanical forces and thermal loads and identifies where the physics uncertainties play a significant role in the engineering requirements. The second lecture presents soft engineering problems of measuring the plasma parameters, feedback control of the plasma and handling the physics data flow and slow controls data flow from a large experiment like ITER. The last three lectures focus on superconductors for fusion. The third lecture reviews the design criteria and manufacturing methods for 6 milestone-conductors of large fusion devices (T-7, T-15, Tore Supra, LHD, W-7X, ITER). The evolution of the...

  17. Academic Training: The ITER project: technological challenges

    CERN Multimedia

    Françoise Benz

    2005-01-01

    2004-2005 ACADEMIC TRAINING PROGRAMME LECTURE SERIES 31 May, 1, 2, 3, June from 11:00 to 12:00 on 31 May and 2, 3, June. From 10:00 to 12:00 on 1 June - Main Auditorium, bldg. 500 The ITER project: technological challenges J. LISTER / CRPP-EPFL, Lausanne and P. BRUZZONE / CRPP-EPFL, Zürich The first lecture reminds us of the ITER challenges, presents hard engineering problems, typically due to mechanical forces and thermal loads and identifies where the physics uncertainties play a significant role in the engineering requirements. The second lecture presents soft engineering problems of measuring the plasma parameters, feedback control of the plasma and handling the physics data flow and slow controls data flow from a large experiment like ITER. The last three lectures focus on superconductors for fusion. The third lecture reviews the design criteria and manufacturing methods for 6 milestone-conductors of large fusion devices (T-7, T-15, Tore Supra, LHD, W-7X, ITER). The evolution of the de...

  18. On iterative procedures of asymptotic inference

    NARCIS (Netherlands)

    K.O. Dzhaparidze (Kacha)

    1983-01-01

    textabstractAbstract  An informal discussion is given on performing an unconstrained maximization or solving non‐linear equations of statistics by iterative methods with the quadratic termination property. It is shown that if a miximized function, e.g. likelihood, is asymptotically quadratic, then f

  19. Iterative Reconstruction for Differential Phase Contrast Imaging

    NARCIS (Netherlands)

    Koehler, T.; Brendel, B.; Roessl, E.

    2011-01-01

    Purpose: The purpose of this work is to combine two areas of active research in tomographic x-ray imaging. The first one is the use of iterative reconstruction techniques. The second one is differential phase contrast imaging (DPCI). Method: We derive an SPS type maximum likelihood (ML) reconstructi

  20. Design and analysis of ITER shield blanket

    Energy Technology Data Exchange (ETDEWEB)

    Ohmori, Junji; Hatano, Toshihisa; Ezato, Kouichiro [Japan Atomic Energy Research Inst., Naka, Ibaraki (Japan). Naka Fusion Research Establishment] [and others

    1998-12-01

    This report includes electromagnetic analyses for ITER shielding blanket modules, fabrication methods for the blanket modules and the back plate, the design and the fabrication methods for port limiter have been investigated. Studies on the runaway electron impact for Be armor have been also performed. (J.P.N.)

  1. Evaluating ITER remote handling middleware concepts

    NARCIS (Netherlands)

    Koning, J. F.; Heemskerk, C. J. M.; Schoen, P.; Smedinga, D.; Boode, A. H.; Hamilton, D. T.

    2013-01-01

    Remote maintenance activities in ITER will be performed by a unique set of hardware systems, supported by an extensive software kit. A layer of middleware will manage and control a complex set of interconnections between teams of operators, hardware devices in various operating theatres, and

  2. ITER faces further five-year delay

    Science.gov (United States)

    Clery, Daniel

    2016-06-01

    The €14bn ITER fusion reactor currently under construction in Cadarache, France, will require an additional cash injection of €4.6bn if it is to start up in 2025 - a target date that is already five years later than currently scheduled.

  3. Iterative solution of the Helmholtz equation

    Energy Technology Data Exchange (ETDEWEB)

    Larsson, E.; Otto, K. [Uppsala Univ. (Sweden)

    1996-12-31

    We have shown that the numerical solution of the two-dimensional Helmholtz equation can be obtained in a very efficient way by using a preconditioned iterative method. We discretize the equation with second-order accurate finite difference operators and take special care to obtain non-reflecting boundary conditions. We solve the large, sparse system of equations that arises with the preconditioned restarted GMRES iteration. The preconditioner is of {open_quotes}fast Poisson type{close_quotes}, and is derived as a direct solver for a modified PDE problem.The arithmetic complexity for the preconditioner is O(n log{sub 2} n), where n is the number of grid points. As a test problem we use the propagation of sound waves in water in a duct with curved bottom. Numerical experiments show that the preconditioned iterative method is very efficient for this type of problem. The convergence rate does not decrease dramatically when the frequency increases. Compared to banded Gaussian elimination, which is a standard solution method for this type of problems, the iterative method shows significant gain in both storage requirement and arithmetic complexity. Furthermore, the relative gain increases when the frequency increases.

  4. Solving Differential Equations Using Modified Picard Iteration

    Science.gov (United States)

    Robin, W. A.

    2010-01-01

    Many classes of differential equations are shown to be open to solution through a method involving a combination of a direct integration approach with suitably modified Picard iterative procedures. The classes of differential equations considered include typical initial value, boundary value and eigenvalue problems arising in physics and…

  5. Wood anatomical classification using iterative character weighing

    NARCIS (Netherlands)

    Hogeweg, P.; Koek-Noorman, J.

    1975-01-01

    In this paper we investigate the pattern of wood anatomical variation in some groups of Rubiaceae (i.e. Cinchoneae, Rondeletieae and Condamineae) by using a numerical pattern detection method which involves character weighing (Hogeweg 1975). In this method character weights are obtained iteratively

  6. Halpern's Iteration in CAT(0 Spaces

    Directory of Open Access Journals (Sweden)

    Satit Saejung

    2010-01-01

    Full Text Available Motivated by Halpern's result, we prove strong convergence theorem of an iterative sequence in CAT(0 spaces. We apply our result to find a common fixed point of a family of nonexpansive mappings. A convergence theorem for nonself mappings is also discussed.

  7. An iterative approach of protein function prediction

    Directory of Open Access Journals (Sweden)

    Chi Xiaoxiao

    2011-11-01

    Full Text Available Abstract Background Current approaches of predicting protein functions from a protein-protein interaction (PPI dataset are based on an assumption that the available functions of the proteins (a.k.a. annotated proteins will determine the functions of the proteins whose functions are unknown yet at the moment (a.k.a. un-annotated proteins. Therefore, the protein function prediction is a mono-directed and one-off procedure, i.e. from annotated proteins to un-annotated proteins. However, the interactions between proteins are mutual rather than static and mono-directed, although functions of some proteins are unknown for some reasons at present. That means when we use the similarity-based approach to predict functions of un-annotated proteins, the un-annotated proteins, once their functions are predicted, will affect the similarities between proteins, which in turn will affect the prediction results. In other words, the function prediction is a dynamic and mutual procedure. This dynamic feature of protein interactions, however, was not considered in the existing prediction algorithms. Results In this paper, we propose a new prediction approach that predicts protein functions iteratively. This iterative approach incorporates the dynamic and mutual features of PPI interactions, as well as the local and global semantic influence of protein functions, into the prediction. To guarantee predicting functions iteratively, we propose a new protein similarity from protein functions. We adapt new evaluation metrics to evaluate the prediction quality of our algorithm and other similar algorithms. Experiments on real PPI datasets were conducted to evaluate the effectiveness of the proposed approach in predicting unknown protein functions. Conclusions The iterative approach is more likely to reflect the real biological nature between proteins when predicting functions. A proper definition of protein similarity from protein functions is the key to predicting

  8. Study for reducing radioactive solid waste at ITER decommissioning period

    Energy Technology Data Exchange (ETDEWEB)

    Sato, Shinichi; Araki, Masanori; Ohmori, Junji; Ohno, Isamu; Sato, Satoshi; Yamauchi, Michinori; Nishitani, Takeo [Japan Atomic Energy Research Inst., Naka, Ibaraki (Japan). Naka Fusion Research Establishment

    2002-11-01

    It is one of the foremost goals for ITER to demonstrate the attractiveness with regard to safety and environmental potential. This implies that the radioactive materials and waste at decommissioning phase should carefully be treated with prescribed regulations. As possible activities during the Coordinated Technical Activity (CTA), the authors have performed a feasibility study for searching the possibility of effective reduction in the activated level as reasonably achievable as possible by taking account of minimum material changes while keeping original design concept and structure. Major induced activation in ITER comes from activated nickel and cobalt so that it is effective for the major structural components to minimize their material contents. Employing less Ni and Co steel in place of high-Ni austenitic stainless steel for blanket shield block, vacuum vessel shield material and TF coil casing has been considered as one of the effective plans to reduce the activated materials at the decommissioning phase. In this study, two less-Ni austenitic stainless steels are evaluated; one is high-Mn austenitic stainless steel JK2 which is developing for jacket material of ITER CS coil and the other is SS204L/ASTM-XM-11 which is also high-Mn steel specified in the popular standards such as American Society of Testing and Material (ASTM). Based on the material changes, activation analyses have been performed to investigate the possibility of reducing radioactive wastes. As a most impressive result, at 40 years after the termination some of main components such as a TF coil casing will reach to the clearance level which is specified by IAEA, and most components will be categorized into extremely low level waste except for limited components. These results will give the appropriate short decommissioning period that is assumed to start at 100 years after the termination in the original design. (author)

  9. ITER diagnostics ex-vessel engineering services

    Energy Technology Data Exchange (ETDEWEB)

    Arumugam, A.P., E-mail: arun.prakash@iter.org; Walker, C.I.; Andrew, P.; Barnsley, R.; Beltran, D.; Bertalot, L.; Dammann, A.; Direz, M.F.; Drevon, J.M.; Encheva, A.; Giacomin, T.; Hourtoule, J.; Kuehn, I.; Lanza, R.; Levesy, B.; Maquet, P.; Patel, K.M.; Patisson, L.; Pitcher, C.S.; Portales, M.; and others

    2013-10-15

    Highlights: • This paper describes about the ITER diagnostics ex-vessel engineering services. • It describes various diagnostics systems, its location and its environment. • Diagnostics interfaces with other services such as the buildings, HVAC, electrical services, cooling water, vacuum, liquid and gas distribution. • All the interfaces with these services are identified and defined. • Buildings services for diagnostics, such as penetrations, local shielding, embedment and temperature control are discussed. -- Abstract: Extensive diagnostics systems will be installed on the ITER machine to provide the measurements necessary to control, evaluate and optimize plasma performance in ITER and to further the understanding of plasma physics. These include measurements of temperature, density, impurity concentration, and particle and energy confinement times. ITER diagnostic systems extend from the center of the Tokamak to the various diagnostic areas, where they are controlled and acquired data is processed. This mainly includes the areas such as ports, port cells, gallery, diagnostics enclosures and cubicle areas. The diagnostics port plugs encloses the front end of the diagnostic systems and the diagnostics building houses the diagnostics equipment, instrumentation and control cubicles. There are several systems providing services to diagnostics. These mainly include ITER buildings, electrical power services, cooling water services, Heating Ventilation and Air Conditioning (HVAC), vacuum services, liquid and gas distribution services, cable engineering, de-tritiation systems, control cubicles, etc. Requirements of these service systems have to be defined, even though many of the diagnostics are at an early stage of development. It is a real challenge to define and to design diagnostics systems considering the constraints imposed by these service systems. This paper summarizes the provision of these services to the individual diagnostics and diagnostics areas

  10. Light field moment imaging with the ptychographic iterative engine

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Zhilong; Pan, Xinchen; Liu, Cheng, E-mail: cheng.liu@hotmail.co.uk, E-mail: ling.wang@biw.kuleuven.be; Zhu, Jianqiang [Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800 (China); Wang, Ling, E-mail: cheng.liu@hotmail.co.uk, E-mail: ling.wang@biw.kuleuven.be [Department of Physics and Astronomy, KU Leuven, 3001, Heverlee (Belgium); NERF, 3001, Heverlee (Belgium)

    2014-10-15

    The recently developed Light Field Moment Imaging (LMI) is adopted to show the stereoscopic structure of the sample studied in Coherent Diffractive Imaging (CDI), where 3D image were always generated with complicated experimental procedure such as the rotation of the sample and time-consuming computation. The animation of large view angle can be generated with LMI very quickly, and the 3D structure of sample can be shown vividly. This method can find many applications for the coherent diffraction imaging with x-ray and electron beams, where a glimpse of the hierarchical structure required and the quick and simple 3D view of object is sufficient. The feasibility of this method is demonstrated theoretically and experimentally with a recently developed CDI method called Ptychographic Iterative Engine.

  11. Flavonoids: prospective drug candidates.

    Science.gov (United States)

    Cazarolli, Luisa Helena; Zanatta, Leila; Alberton, Elga Heloisa; Figueiredo, Maria Santos Reis Bonorino; Folador, Poliane; Damazio, Rosangela Guollo; Pizzolatti, Moacir Geraldo; Silva, Fátima Regina Mena Barreto

    2008-11-01

    The purpose of this review is to discuss the recent developments related to the chemistry and medicinal properties of flavonoids. Major flavonoids that show well categorized structures and well defined structure function-relationships are: flavans, flavanones, flavones, flavanonols, flavonols, catechins, anthocyanidins and isoflavone. The biological properties of flavonoids include antioxidant, anti-inflamatory, antitumoral, antiviral and antibacterial, as well as a direct cytoprotective effect on coronary and vascular systems, the pancreas and the liver. These characteristics place them among the most attractive natural substances available to enrich the current therapy options.

  12. Development of ITER relevant laser techniques for deposited layer characterisation and tritium inventory

    Energy Technology Data Exchange (ETDEWEB)

    Malaquias, A., E-mail: artur.malaquias@jet.efda.org [Associação EURATOM/IST, Instituto de Plasmas e Fusão Nuclear, Instituto Superior Técnico, Universidade Técnica de Lisboa, Av. Rovisco Pais 1, 1049-001, Lisboa (Portugal); EFDA-CSU, Culham Science Centre, Abingdon OX14 3DB (United Kingdom); Philipps, V.; Huber, A. [Institute for Energy Research – Plasma Physics, Forschungszentrum Jülich GmbH, Association EURATOM-FZJ (Germany); Hakola, A.; Likonen, J. [VTT, Association EURATOM-TEKES, P.O. Box 1000, 02044 VTT (Finland); Kolehmainen, J.; Tervakangas, S. [DIARC-Technology Inc., Kattilalaaksontie 1, 02330 Espoo (Finland); Aints, M.; Paris, P.; Laan, M.; Lissovski, A. [Institute of Physics, University of Tartu, Association EURATOM-TEKES, Tahe 4, Tartu 51010 (Estonia); Almaviva, S.; Caneve, L.; Colao, F. [ENEA, UTAPRAD-DIM, C.R. Frascati, P.O. Box 65, 00044 Frascati, Roma (Italy); Maddaluno, G. [Associazione EURATOM-ENEA sulla Fusione, C. R. Frascati, P.O. Box 65, 00044 Frascati, Roma (Italy); Kubkowska, M.; Gasior, P. [Institute of Plasma Physics and Laser Microfusion, Association EURATOM/IPPLM, 00-908 Warsaw, P.O. Box 49, Hery St. 23 (Poland); Meiden, H.J. van der; Lof, A.R.; Zeijlmans van Emmichoven, P.A. [FOM Institute for Plasma Physics Rijnhuizen, Association EURATOM-FOM, Trilateral Euregio Cluster, P.O. Box 1207, 3430 BE Nieuwegein (Netherlands); and others

    2013-07-15

    Laser Induced Breakdown Spectroscopy (LIBS) is a potential candidate to monitor the layer composition and fuel retention during and after plasma shots on specific locations of the main chamber and divertor of ITER. This method is being investigated in a cooperative research programme on plasma devices such as TEXTOR, FTU, MAGNUM-PSI and in other various laboratorial experiments. In this paper LIBS results from targets of D–H-rich carbon films and mixed W–Al–C deposits on bulk tungsten substrates are reported (simulating ITER-like deposits with Al as proxy for Be). Two independent methods, one to determine the relative elemental composition and the other the absolute contents of the target based on the experimental LIBS signals are proposed. The results show that LIBS has the capability to provide the relative concentrations of the elements on the deposited layer when the experimental conditions on the targets surface are identical to the calibration samples.

  13. Crystal structure, stability, and optoelectronic properties of the organic-inorganic wide-band-gap perovskite CH3NH3BaI3 : Candidate for transparent conductor applications

    Science.gov (United States)

    Kumar, Akash; Balasubramaniam, K. R.; Kangsabanik, Jiban; Vikram, Alam, Aftab

    2016-11-01

    Structural stability, electronic structure, and optical properties of CH3NH3BaI3 hybrid perovskite are examined from theory as well as experiment. Solution-processed thin films of CH3NH3BaI3 exhibited a high transparency in the wavelength range of 400-825 nm (1.5-3.1 eV for which the photon current density is highest in the solar spectrum) which essentially justifies a high band gap of 4 eV obtained by theoretical estimation. Also, the x-ray diffraction patterns of the thin films match well with the {00 l } peaks of the simulated pattern obtained from the relaxed unit cell of CH3NH3BaI3 , crystallizing in the I 4 /m c m space group, with lattice parameters, a =9.30 Å, c =13.94 Å. Atom projected density of state and band structure calculations reveal the conduction and valence band edges to be comprised primarily of barium d orbitals and iodine p orbitals, respectively. The larger band gap of CH3NH3BaI3 compared to CH3NH3PbI3 can be attributed to the lower electronegativity coupled with the lack of d orbitals in the valence band of Ba2 +. A more detailed analysis reveals the excellent chemical and mechanical stability of CH3NH3BaI3 against humidity, unlike its lead halide counterpart, which degrades under such conditions. We propose La to be a suitable dopant to make this compound a promising candidate for transparent conductor applications, especially for all perovskite solar cells. This claim is supported by our calculated results on charge concentration, effective mass, and vacancy formation energies.

  14. Chevron beam dump for ITER edge Thomson scattering system.

    Science.gov (United States)

    Yatsuka, E; Hatae, T; Vayakis, G; Bassan, M; Itami, K

    2013-10-01

    This paper contains the design of the beam dump for the ITER edge Thomson scattering system and mainly concerns its lifetime under the harsh thermal and electromagnetic loads as well as tight space allocation. The lifetime was estimated from the multi-pulse laser-induced damage threshold. In order to extend its lifetime, the structure of the beam dump was optimized. A number of bent sheets aligned parallel in the beam dump form a shape called a chevron which enables it to avoid the concentration of the incident laser pulse energy. The chevron beam dump is expected to withstand thermal loads due to nuclear heating, radiation from the plasma, and numerous incident laser pulses throughout the entire ITER project with a reasonable margin for the peak factor of the beam profile. Structural analysis was also carried out in case of electromagnetic loads during a disruption. Moreover, detailed issues for more accurate assessments of the beam dump's lifetime are clarified. Variation of the bi-directional reflection distribution function (BRDF) due to erosion by or contamination of neutral particles derived from the plasma is one of the most critical issues that needs to be resolved. In this paper, the BRDF was assumed, and the total amount of stray light and the absorbed laser energy profile on the beam dump were evaluated.

  15. Chevron beam dump for ITER edge Thomson scattering system

    Science.gov (United States)

    Yatsuka, E.; Hatae, T.; Vayakis, G.; Bassan, M.; Itami, K.

    2013-10-01

    This paper contains the design of the beam dump for the ITER edge Thomson scattering system and mainly concerns its lifetime under the harsh thermal and electromagnetic loads as well as tight space allocation. The lifetime was estimated from the multi-pulse laser-induced damage threshold. In order to extend its lifetime, the structure of the beam dump was optimized. A number of bent sheets aligned parallel in the beam dump form a shape called a chevron which enables it to avoid the concentration of the incident laser pulse energy. The chevron beam dump is expected to withstand thermal loads due to nuclear heating, radiation from the plasma, and numerous incident laser pulses throughout the entire ITER project with a reasonable margin for the peak factor of the beam profile. Structural analysis was also carried out in case of electromagnetic loads during a disruption. Moreover, detailed issues for more accurate assessments of the beam dump's lifetime are clarified. Variation of the bi-directional reflection distribution function (BRDF) due to erosion by or contamination of neutral particles derived from the plasma is one of the most critical issues that needs to be resolved. In this paper, the BRDF was assumed, and the total amount of stray light and the absorbed laser energy profile on the beam dump were evaluated.

  16. The complex Jacobi iterative method for three-dimensional wide-angle beam propagation.

    Science.gov (United States)

    Le, Khai Q; Godoy-Rubio, R; Bienstman, Peter; Hadley, G Ronald

    2008-10-13

    A new complex Jacobi iterative technique adapted for the solution of three-dimensional (3D) wide-angle (WA) beam propagation is presented. The beam propagation equation for analysis of optical propagation in waveguide structures is based on a novel modified Padé(1,1) approximant operator, which gives evanescent waves the desired damping. The resulting approach allows more accurate approximations to the true Helmholtz equation than the standard Padé approximant operators. Furthermore, a performance comparison of the traditional direct matrix inversion and this new iterative technique for WA-beam propagation method is reported. It is shown that complex Jacobi iteration is faster and better-suited for large problems or structures than direct matrix inversion.

  17. Development of a coarse-grained water forcefield via multistate iterative Boltzmann inversion

    CERN Document Server

    Moore, Timothy C; McCabe, Clare

    2015-01-01

    A coarse-grained water model is developed using multistate iterative Boltzmann inversion. Following previous work, the k-means algorithm is used to dynamically map multiple water molecules to a single coarse-grained bead, allowing the use of structure-based coarse-graining methods. The model is derived to match the bulk and interfacial properties of liquid water and improves upon previous work that used single state iterative Boltzmann inversion. The model accurately reproduces the density and structural correlations of water at 305 K and 1.0 atm, stability of a liquid droplet at 305 K, and shows little tendency to crystallize at physiological conditions. This work also illustrates several advantages of using multistate iterative Boltzmann inversion for deriving generally applicable coarse-grained forcefields.

  18. Optimised Iteration in Coupled Monte Carlo - Thermal-Hydraulics Calculations

    Science.gov (United States)

    Hoogenboom, J. Eduard; Dufek, Jan

    2014-06-01

    This paper describes an optimised iteration scheme for the number of neutron histories and the relaxation factor in successive iterations of coupled Monte Carlo and thermal-hydraulic reactor calculations based on the stochastic iteration method. The scheme results in an increasing number of neutron histories for the Monte Carlo calculation in successive iteration steps and a decreasing relaxation factor for the spatial power distribution to be used as input to the thermal-hydraulics calculation. The theoretical basis is discussed in detail and practical consequences of the scheme are shown, among which a nearly linear increase per iteration of the number of cycles in the Monte Carlo calculation. The scheme is demonstrated for a full PWR type fuel assembly. Results are shown for the axial power distribution during several iteration steps. A few alternative iteration method are also tested and it is concluded that the presented iteration method is near optimal.

  19. Methods used for research regarding iteration in instructional design

    NARCIS (Netherlands)

    Verstegen, D.M.L.

    2004-01-01

    This paper focuses on the search for suitable research methods for research regarding iteration in instructional design. More specifically my research concerned the question how instructional designers can be supported during an iterative design process. Although instructional design and development

  20. Model Based Iterative Reconstruction for Bright Field Electron Tomography (Postprint)

    Science.gov (United States)

    2013-02-01

    Reconstruction Technique ( SIRT ) are applied to the data. Model based iterative reconstruction (MBIR) provides a powerful framework for tomographic...the reconstruction when the typical algorithms such as Filtered Back Projection (FBP) and Simultaneous Iterative Reconstruction Technique ( SIRT ) are

  1. Food cravings among bariatric surgery candidates.

    Science.gov (United States)

    Crowley, Nina; Madan, Alok; Wedin, Sharlene; Correll, Jennifer A; Delustro, Laura M; Borckardt, Jeffery J; Byrne, T Karl

    2014-01-01

    Food cravings are common, more prevalent in the obese, and may differ in those who pursue surgical treatment for obesity. Food craving tools are most often validated in non-clinical, non-obese samples. In this retrospective study, 227 bariatric surgery candidates at a large medical center completed the Food Cravings Questionnaire-Trait (FCQ-T). The aim was to explore the factor structure of the FCQ-T. Principal components analysis with varimax rotation revealed a seven-factor structure that explained 70.89 % of the variance. The seven factors were: (1) preoccupation with food, (2) emotional triggers, (3) environmental cues, (4) loss of control, (5) relief from negative emotions, (6) guilt, and (7) physiological response. The preoccupation with food factor accounted for 49.46 % of the variance in responses. Unlike other populations, food cravings in bariatric surgery candidates appear to be related most to preoccupations with food.

  2. Concatenated coding system with iterated sequential inner decoding

    DEFF Research Database (Denmark)

    Jensen, Ole Riis; Paaske, Erik

    1995-01-01

    We describe a concatenated coding system with iterated sequential inner decoding. The system uses convolutional codes of very long constraint length and operates on iterations between an inner Fano decoder and an outer Reed-Solomon decoder......We describe a concatenated coding system with iterated sequential inner decoding. The system uses convolutional codes of very long constraint length and operates on iterations between an inner Fano decoder and an outer Reed-Solomon decoder...

  3. A short remark on fractional variational iteration method

    Energy Technology Data Exchange (ETDEWEB)

    He, Ji-Huan, E-mail: hejihuan@suda.edu.cn [National Engineering Laboratory for Modern Silk, College of Textile and Engineering, Soochow University, 199 Ren-ai Road, Suzhou 215123 (China)

    2011-09-05

    This Letter compares the classical variational iteration method with the fractional variational iteration method. The fractional complex transform is introduced to convert a fractional differential equation to its differential partner, so that its variational iteration algorithm can be simply constructed. -- Highlights: → The variational iteration method and its fractional modification are compared. → The demerits arising are overcome by the fractional complex transform. → The Letter provides a powerful tool to solving fractional differential equations.

  4. Progress of the ECRH Upper Launcher design for ITER

    Energy Technology Data Exchange (ETDEWEB)

    Strauss, D., E-mail: dirk.strauss@kit.edu [Karlsruhe Institute of Technology, Assoc. KIT-EURATOM, D-76021 Karlsruhe (Germany); Aiello, G. [Karlsruhe Institute of Technology, Assoc. KIT-EURATOM, D-76021 Karlsruhe (Germany); Bruschi, A. [Istituto di Fisica del Plasma CNR, Euratom Association, 20125 Milano (Italy); Chavan, R. [Centre de Recherches en Physique des Plasmas, CRPP–EPFL, CH-1015 Lausanne (Switzerland); Farina, D.; Figini, L. [Istituto di Fisica del Plasma CNR, Euratom Association, 20125 Milano (Italy); Gagliardi, M.; Garcia, V. [Fusion for Energy, Barcelona (Spain); Goodman, T.P. [Centre de Recherches en Physique des Plasmas, CRPP–EPFL, CH-1015 Lausanne (Switzerland); Grossetti, G. [Karlsruhe Institute of Technology, Assoc. KIT-EURATOM, D-76021 Karlsruhe (Germany); Heemskerk, C. [Heemskerk Innovative Technology, Merelhof 2, 2172 HZ Sassenheim (Netherlands); Henderson, M.A. [ITER Organization, 13108 Saint-Paul-lez-Durance (France); Kasparek, W. [Institut für Plasmaforschung, IPF, D-70569 Stuttgart (Germany); Krause, A.; Landis, J.-D. [Centre de Recherches en Physique des Plasmas, CRPP–EPFL, CH-1015 Lausanne (Switzerland); Meier, A. [Karlsruhe Institute of Technology, Assoc. KIT-EURATOM, D-76021 Karlsruhe (Germany); Moro, A.; Platania, P. [Istituto di Fisica del Plasma CNR, Euratom Association, 20125 Milano (Italy); Plaum, B. [Institut für Plasmaforschung, IPF, D-70569 Stuttgart (Germany); Poli, E. [Max-Planck-IPP, Euratom Association, D-85748 Garching (Germany); and others

    2014-10-15

    The design of the ITER ECRH system provides 20 MW millimeter wave power for central plasma heating and MHD stabilization. The system consists of an array of 24 gyrotrons with power supplies coupled to a set of transmission lines guiding the beams to the four upper and the equatorial launcher. The front steering upper launcher design described herein has passed successfully the preliminary design review, and it is presently in the final design stage. The launcher consists of a millimeter wave system and steering mechanism with neutron shielding integrated into an upper port plug with the plasma facing blanket shield module (in-vessel) and a set of ex-vessel waveguides connecting the launcher to the transmission lines. Part of the transmission lines are the ultra-low loss CVD torus diamond windows and a shutter valve, a miter bend section and the feedthroughs integrated in the plug closure plate. These components are connected by corrugated waveguides and form together the first confinement system (FCS). In-vessel, the millimeter-wave system includes a quasi-optical beam propagation system including four mirror sets and a front steering mirror. The millimeter wave system is integrated into a specifically optimized upper port plug providing structural stability to withstand plasma disruption forces and the high heat load from the plasma side with a dedicated blanket shield module. A recent update in the ITER interface definition has resulted in the recession of the upper port plug first wall panels, which is now integrated into the design. Apart from the millimeter wave system the upper port plug houses also a set of shield blocks which provide neutron shielding. An overview of the actual ITER ECRH Upper Launcher is given together with some highlights of the design.

  5. Engineering activities on the ITER representative diagnostic equatorial port plug

    Energy Technology Data Exchange (ETDEWEB)

    Meunier, L. [Association Euratom CEA, CEA/DSM/IRFM (France)], E-mail: lmeunier@cea.fr; Doceul, L.; Salasca, S.; Martins, J.-P.; Jullien, F.; Dechelle, Christian; Bidaud, Pierre; Pilard, Vincent; Terra, Alexis; Ogea, Mathieu [Association Euratom CEA, CEA/DSM/IRFM (France); Ciattaglia, Emanuela [EFDA CSU, Garching (Germany); Walker, Christopher [ITER International Organisation (France)

    2009-06-15

    Most of ITER diagnostic systems are integrated in port plugs, which are water cooled stainless steel structures inserted into the vacuum vessel ports. The port plug must provide basic functions such as neutron and gamma shielding, supporting the first wall armour (BSM), closing the vacuum vessel ports, while supporting the diagnostic equipments. ITER diagnostic port plug must resist a severe environment like high temperature due to neutron interaction with the structures and high electromechanical loading during disruptions events. CEA has contributed to the design and integration tasks in the frame of the representative equatorial port plug EQ no. 01, in particular on the engineering, structural and thermal finite element analysis. These detailed analyses have highlighted some design issues which were worked out through different solutions. This paper contains a description of the engineering activities performed such as: -The static mechanical calculations of the top plate closure system under disruption load. -The static mechanical calculations of the BSM attachment to the port plug. These two first studies led to design changes proposals which significantly improved the behaviour of the structures but also showed that the safety margin with respect to design limits is quite low. -The design of a Diagnostic Shield Module (DSM) integrated inside the port plug and a proposition of attachment scheme, with respect to disruption loads. The manufacturing of the DSM has been taken into account, as well as diagnostic integration inside the structure and maintenance aspects. -The thermal assessment of the port plug under neutronic load during normal operation, with the optimization of the cooling system. The maximum temperature calculated in normal operation has been reduced from 900 deg. C to less than 400 deg. C in the front plate; and the cooling arrangement at the back of the port plug has been simplified without important temperature increase.

  6. An iterative algorithm for solving a class of matrix equations

    Institute of Scientific and Technical Information of China (English)

    Minghui WANG; Yan FENG

    2009-01-01

    In this paper,an iterative algorithm is presented to solve the Sylvester and Lyapunov matrix equations.By this iterative algorithm,for any initial matrix X1,a solution X* can be obtained within finite iteration steps in the absence of roundoff errors.Some examples illustrate that this algorithm is very efficient and better than that of [1] and [2].

  7. Iterative algorithms to approximate canonical Gabor windows: Computational aspects

    DEFF Research Database (Denmark)

    Janssen, A.J.E.M; Søndergaard, Peter Lempel

    In this paper we investigate the computational aspects of some recently proposed iterative methods for approximating the canonical tight and canonical dual window of a Gabor frame (g,a,b). The iterations start with the window g while the iteration steps comprise the window g, the k^th iterand...

  8. Iterative algorithms to approximate canonieal Gabor windows: Computational aspects

    DEFF Research Database (Denmark)

    Janssen, A. J. E. M.; Søndergaard, Peter Lempel

    2007-01-01

    In this article we investigate the computational aspects of some recently proposed iterative methods for approximating the canonical tight and canonical dual window of a Gabor frame (g, a, b). The iterations start with the window g while the iteration steps comprise the window g, the k(th) iterand...

  9. Efficient use of iterative solvers in nested topology optimization

    DEFF Research Database (Denmark)

    Amir, Oded; Stolpe, Mathias; Sigmund, Ole

    2009-01-01

    by a Krylov subspace iterative solver. By choosing convergence criteria for the iterative solver that are strongly related to the optimization objective and to the design sensitivities, it is possible to terminate the iterative solution of the nested equations earlier compared to traditional convergence...

  10. General Object-oriented Framework for Iterative Optimization Algorithms

    OpenAIRE

    Mornar, Vedran; Vanjak, Zvonimir

    2001-01-01

    It is usually impossible to exactly solve the hard optimization problems. One is thus directed to iterative algorithms. In implementation of these iterative algorithms, some common characteristics can be observed, which can be generalized in an object-oriented framework. This can significantly reduce the time needed for implementation of an iterative algorithm.

  11. Extortion outperforms generosity in iterated Prisoners' Dilemma

    CERN Document Server

    Xu, Bin; Lien, Jaimie W; Zheng, Jie; Wang, Zhijian

    2015-01-01

    Promoting cooperation is an intellectual challenge in the social sciences, for which the iterated Prisoners' Dilemma (IPD) is a fundamental framework. The traditional view that there exists no simple ultimatum strategy whereby one player can unilaterally control the share of the surplus has been challenged by a new class of "zero-determinant" (ZD) strategies raised by Press and Dyson. In particular, the extortionate strategies can subdue the opponent and obtain higher scores. However, no empirical evidence has yet been found to support this theoretical finding. In a long-run laboratory experiment of the iterated Prisoners' Dilemma pairing each human subject with a computer co-player, we demonstrate that the extortionate strategy indeed outperforms the generous strategy against human subjects. Our results show that the extortionate strategy achieves higher scores than the generous strategy, the extortionate strategy promotes the cooperation rate to a similar level as the generous strategy does, and the human s...

  12. Iterative learning control an optimization paradigm

    CERN Document Server

    Owens, David H

    2016-01-01

    This book develops a coherent theoretical approach to algorithm design for iterative learning control based on the use of optimization concepts. Concentrating initially on linear, discrete-time systems, the author gives the reader access to theories based on either signal or parameter optimization. Although the two approaches are shown to be related in a formal mathematical sense, the text presents them separately because their relevant algorithm design issues are distinct and give rise to different performance capabilities. Together with algorithm design, the text demonstrates that there are new algorithms that are capable of incorporating input and output constraints, enable the algorithm to reconfigure systematically in order to meet the requirements of different reference signals and also to support new algorithms for local convergence of nonlinear iterative control. Simulation and application studies are used to illustrate algorithm properties and performance in systems like gantry robots and other elect...

  13. Iterative Brinkman penalization for remeshed vortex methods

    Science.gov (United States)

    Hejlesen, Mads Mølholm; Koumoutsakos, Petros; Leonard, Anthony; Walther, Jens Honoré

    2015-01-01

    We introduce an iterative Brinkman penalization method for the enforcement of the no-slip boundary condition in remeshed vortex methods. In the proposed method, the Brinkman penalization is applied iteratively only in the neighborhood of the body. This allows for using significantly larger time steps, than what is customary in the Brinkman penalization, thus reducing its computational cost while maintaining the capability of the method to handle complex geometries. We demonstrate the accuracy of our method by considering challenging benchmark problems such as flow past an impulsively started cylinder and normal to an impulsively started and accelerated flat plate. We find that the present method enhances significantly the accuracy of the Brinkman penalization technique for the simulations of highly unsteady flows past complex geometries.

  14. ITER Shape Controller and Transport Simulations

    Energy Technology Data Exchange (ETDEWEB)

    Casper, T A; Meyer, W H; Pearlstein, L D; Portone, A

    2007-05-31

    We currently use the CORSICA integrated modeling code for scenario studies for both the DIII-D and ITER experiments. In these simulations, free- or fixed-boundary equilibria are simultaneously converged with thermal evolution determined from transport models providing temperature and current density profiles. Using a combination of fixed boundary evolution followed by free-boundary calculation to determine the separatrix and coil currents. In the free-boundary calculation, we use the state-space controller representation with transport simulations to provide feedback modeling of shape, vertical stability and profile control. In addition to a tightly coupled calculation with simulator and controller imbedded inside CORSICA, we also use a remote procedure call interface to couple the CORSICA non-linear plasma simulations to the controller environments developed within the Mathworks Matlab/Simulink environment. We present transport simulations using full shape and vertical stability control with evolution of the temperature profiles to provide simulations of the ITER controller and plasma response.

  15. Mahalanobis Distance Based Iterative Closest Point

    DEFF Research Database (Denmark)

    Hansen, Mads Fogtmann; Blas, Morten Rufus; Larsen, Rasmus

    2007-01-01

    the notion of a mahalanobis distance map upon a point set with associated covariance matrices which in addition to providing correlation weighted distance implicitly provides a method for assigning correspondence during alignment. This distance map provides an easy formulation of the ICP problem that permits......This paper proposes an extension to the standard iterative closest point method (ICP). In contrast to ICP, our approach (ICP-M) uses the Mahalanobis distance to align a set of shapes thus assigning an anisotropic independent Gaussian noise to each point in the reference shape. The paper introduces...... a fast optimization. Initially, the covariance matrices are set to the identity matrix, and all shapes are aligned to a randomly selected shape (equivalent to standard ICP). From this point the algorithm iterates between the steps: (a) obtain mean shape and new estimates of the covariance matrices from...

  16. Iterative Estimation in Turbo Equalization Process

    Directory of Open Access Journals (Sweden)

    MORGOS Lucian

    2014-05-01

    Full Text Available This paper presents the iterative estimation in turbo equalization process. Turbo equalization is the process of reception in which equalization and decoding are done together, not as separate processes. For the equalizer to work properly, it must receive before equalization accurate information about the value of the channel impulse response. This estimation of channel impulse response is done by transmission of a training sequence known at reception. Knowing both the transmitted and received sequence, it can be calculated estimated value of the estimated the channel impulse response using one of the well-known estimation algorithms. The estimated value can be also iterative recalculated based on the sequence data available at the output of the channel and estimated sequence data coming from turbo equalizer output, thereby refining the obtained results.

  17. An Adaptive Iterated Nonlocal Interferometry Filtering Method

    Directory of Open Access Journals (Sweden)

    Lin Xue

    2014-04-01

    Full Text Available Interferometry filtering is one of the key steps in obtain high-precision Digital Elevation Model (DEM and Digital Orthophoto Map (DOM. In the case of low-correlation or complicated topography, traditional phase filtering methods fail in balancing noise elimination and phase preservation, which leads to inaccurate interferometric phase. This paper proposed an adaptive iterated nonlocal interferometry filtering method to deal with the problem. Based on the thought of nonlocal filtering, the proposed method filters the image with utilization of the image redundancy information. The smoothing parameter of the method is adaptive to the interferometry, and automatic iteration, in which the window size is adjusted, is applied to improve the filtering precision. Validity of the proposed method is verified by simulated and real data. Comparison with existed methods is given at the same time.

  18. ITER Materials R & D Data Bank

    Science.gov (United States)

    Tanaka, Shigeru; Matera, R.; Kalinin, G.; Barabash, V.; Mohri, K.

    To keep traceability of many valuable raw data that were experimentally obtained in the ITER Technology R&D Tasks related to materials for In-Vessel Components, and to easily make the best use of these data in design activities, the `ITER Materials R&D Data Bank' has been built up, with the use of Excel TM spread sheets. Compared with existing material data banks, this data bank is unique in the following respects: (1) In addition to thermo-mechanical properties of single materials (beryllium, tungsten, carbon-based materials, copper alloys and stainless steels), thermo-mechanical properties (including neutron irradiation effects) for various kinds of joints between these materials, and the results of thermal fatigue tests of mock-ups are collected. (2) As for plasma facing materials (beryllium, tungsten and carbon), experimental data on plasma-material interactions such as sputtering, disruption erosion, and hydrogen-isotope trapping and release are collected.

  19. New iterative solvers for the NAG Libraries

    Energy Technology Data Exchange (ETDEWEB)

    Salvini, S.; Shaw, G. [Numerical Algorithms Group Ltd., Oxford (United Kingdom)

    1996-12-31

    The purpose of this paper is to introduce the work which has been carried out at NAG Ltd to update the iterative solvers for sparse systems of linear equations, both symmetric and unsymmetric, in the NAG Fortran 77 Library. Our current plans to extend this work and include it in our other numerical libraries in our range are also briefly mentioned. We have added to the Library the new Chapter F11, entirely dedicated to sparse linear algebra. At Mark 17, the F11 Chapter includes sparse iterative solvers, preconditioners, utilities and black-box routines for sparse symmetric (both positive-definite and indefinite) linear systems. Mark 18 will add solvers, preconditioners, utilities and black-boxes for sparse unsymmetric systems: the development of these has already been completed.

  20. Europe wrestles with ITER site bid

    CERN Multimedia

    Feder, T

    2003-01-01

    "The European Union is in a quandary over whether to put forward the French or Spanish site to host ITER, a $5 billion magnetic fusion experiment intended to prove the feasability of fusion energy. The decision is set for 27 November, with the final site selection, between the victorious European bid and bids from Canada and Japan, to follow within a couple of months" (1 page)

  1. Iterative Reconstruction of Coded Source Neutron Radiographs

    Energy Technology Data Exchange (ETDEWEB)

    Santos-Villalobos, Hector J [ORNL; Bingham, Philip R [ORNL; Gregor, Jens [University of Tennessee, Knoxville (UTK)

    2012-01-01

    Use of a coded source facilitates high-resolution neutron imaging but requires that the radiographic data be deconvolved. In this paper, we compare direct deconvolution with two different iterative algorithms, namely, one based on direct deconvolution embedded in an MLE-like framework and one based on a geometric model of the neutron beam and a least squares formulation of the inverse imaging problem.

  2. The Iterative Method of Generalized -Concave Operators

    Directory of Open Access Journals (Sweden)

    Zhou Yanqiu

    2011-01-01

    Full Text Available We define the concept of the generalized -concave operators, which generalize the definition of the -concave operators. By using the iterative method and the partial ordering method, we prove the existence and uniqueness of fixed points of this class of the operators. As an example of the application of our results, we show the existence and uniqueness of solutions to a class of the Hammerstein integral equations.

  3. ITER plasma safety interface models and assessments

    Energy Technology Data Exchange (ETDEWEB)

    Uckan, N.A. [Oak Ridge National Lab., TN (United States); Bartels, H-W. [ITER San Diego Joint Work Site, La Jolla, CA (United States); Honda, T. [Hitachi Ltd., Ibaraki (Japan). Hitachi Research Lab.; Putvinski, S. [ITER San Diego Joint Work Site, La Jolla, CA (United States); Amano, T. [National Inst. for Fusion Science, Nagoya (Japan); Boucher, D.; Post, D.; Wesley, J. [ITER San Diego Joint Work Site, La Jolla, CA (United States)

    1996-12-31

    Physics models and requirements to be used as a basis for safety analysis studies are developed and physics results motivated by safety considerations are presented for the ITER design. Physics specifications are provided for enveloping plasma dynamic events for Category I (operational event), Category II (likely event), and Category III (unlikely event). A safety analysis code SAFALY has been developed to investigate plasma anomaly events. The plasma response to ex-vessel component failure and machine response to plasma transients are considered.

  4. Iterative solution of high order compact systems

    Energy Technology Data Exchange (ETDEWEB)

    Spotz, W.F.; Carey, G.F. [Univ. of Texas, Austin, TX (United States)

    1996-12-31

    We have recently developed a class of finite difference methods which provide higher accuracy and greater stability than standard central or upwind difference methods, but still reside on a compact patch of grid cells. In the present study we investigate the performance of several gradient-type iterative methods for solving the associated sparse systems. Both serial and parallel performance studies have been made. Representative examples are taken from elliptic PDE`s for diffusion, convection-diffusion, and viscous flow applications.

  5. AFFINE TRANSFORMATION IN RANDOM ITERATED FUNCTION SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    熊勇; 史定华

    2001-01-01

    Random iterated function systems (IFSs) is discussed, which is one of the methods for fractal drawing. A certain figure can be reconstructed by a random IFS. One approach is presented to determine a new random IFS, that the figure reconstructed by the new random IFS is the image of the origin figure reconstructed by old IFS under a given affine transformation. Two particular examples are used to show this approach.

  6. Three-dimensional measurement method based on mesh candidates assisted with structured light%基于结构光辅助的网格候选点三维测量方法

    Institute of Scientific and Technical Information of China (English)

    刘彬; 徐刚; 张文明; 李海滨

    2009-01-01

    光学三维测量技术是计算机视觉领域中最为活跃的研究主题之一.针对双目立体视觉三维测量方法中无纹理物体表面测量误差较大的问题,提出一种基于结构光投影辅助的网格候选点三维测量方法.设计灰度单调变化的锯齿波图案投射在被测场景中,有助于使三维网格候选点投影像点间的灰度差异最大化,依此提高系统的测量精度,实现了主动测量方法和被动测量方法的有效结合.通过3DS MAX和MATLAB软件平台下的仿真实验,验证了结构光辅助的网格候选点测量方法在计算精度上具有明显优势,且不会增加系统的复杂度,扩展了网格候选点三维测量方法的适用范围.%Optical three-dimensional measurement technology is one of the most active research topics in computer vision domain. Aiming at the problem of larger measurement error for the surface without texture, a mesh candidate based method with structured light illuminating is introduced for adding texture on the scene via further research of the preparatory work. The illuminating sawtooth pattern projected from the mesh candidates in the scene makes the similarity of the corresponding points more distinguishable. The active and passive optical measuring methods are combined effectively. Simulation experiments on 3DS MAX and MATLAB software platforms prove that the precision of the system has been improved obviously.

  7. Testing and modeling of diffusion bonded prototype optical windows under ITER conditions

    Energy Technology Data Exchange (ETDEWEB)

    Jacobs, M. [Flemish Inst. for Technological Research, Mol (Belgium); Van Oost, G. [Dept. of Applied Physics, Ghent Univ., Ghent (Belgium); Degrieck, J.; De Baere, I. [Dept. of Materials Science and Engineering, Ghent Univ., Ghent (Belgium); Gusarov, A. [Belgian Nuclear Research Center, Mol (Belgium); Gubbels, F. [TNO, Eindhoven (Netherlands); Massaut, V. [Belgian Nuclear Research Center, Mol (Belgium)

    2011-07-01

    Glass-metal joints are a part of ITER optical diagnostics windows. These joints must be leak tight for the safety (presence of tritium in ITER) and to preserve the vacuum. They must also withstand the ITER environment: temperatures up to 220 deg.C and fast neutron fluxes of {approx}3.10{sup 9} n/cm{sup 2}.s. At the moment, little information is available about glass-metal joints suitable for ITER. Therefore, we performed mechanical and thermal tests on some prototypes of an aluminium diffusion bonded optical window. Finite element modeling with Abaqus code was used to understand the experimental results. The prototypes were helium leaking probably due to very tiny cracks in the interaction layer between the steel and the aluminium. However, they were all able to withstand a thermal cycling test up to 200 deg. C; no damage could be seen after the tests by visual inspection. The prototypes successfully passed push-out test with a 500 N load. During the destructive push-out tests the prototypes broke at a 6-12 kN load between the aluminium layer and the steel or the glass, depending on the surface quality of the glass. The microanalysis of the joints has also been performed. The finite element modeling of the push-out tests is in a reasonable agreement with the experiments. According to the model, the highest thermal stress is created in the aluminium layer. Thus, the aluminium joint seems to be the weakest part of the prototypes. If this layer is improved, it will probably make the prototype helium leak tight and as such, a good ITER window candidate. (authors)

  8. The dynamics of iterated transportation simulations

    Energy Technology Data Exchange (ETDEWEB)

    Nagel, K.; Rickert, M.; Simon, P.M.

    1998-12-01

    Transportation-related decisions of people often depend on what everybody else is doing. For example, decisions about mode choice, route choice, activity scheduling, etc., can depend on congestion, caused by the aggregated behavior of others. From a conceptual viewpoint, this consistency problem causes a deadlock, since nobody can start planning because they do not know what everybody else is doing. It is the process of iterations that is examined in this paper as a method for solving the problem. In this paper, the authors concentrate on the aspect of the iterative process that is probably the most important one from a practical viewpoint, and that is the ``uniqueness`` or ``robustness`` of the results. Also, they define robustness more in terms of common sense than in terms of a mathematical formalism. For this, they do not only want a single iterative process to converge, but they want the result to be independent of any particular implementation. The authors run many computational experiments, sometimes with variations of the same code, sometimes with totally different code, in order to see if any of the results are robust against these changes.

  9. ITER: Promises unkept ? (2/2)

    CERN Document Server

    CERN. Geneva

    2008-01-01

    Fusion power as the source of energy on Earth has been the dream of mankind ever since the principles were understood. ITER, the Latin word for “the way”, is the world’s largest Fusion device presently under construction in Cadarache, France. Supported by the People’s Republic of China, the European Atomic Energy Community, India, Japan, the Republic of Korea, the Russian Federation, and the United States of America, an international organization was founded after the signature of the Joint ITER Agreement in October of 2006. The goal is to build a Fusion reactor with a power amplification of 10, a total fusion power of 500 MW or more operating at extended burn times of 400-3000 seconds, with Deuterium and Tritium as its basic fuel. Following a short introduction into fusion science principles, the history of thermo nuclear fusion will be covered. Finally more recent construction projects around the world, their latest achievements and the path to ITER will be described. Technological and scientific c...

  10. ITER: Promises unkept ? (1/2)

    CERN Document Server

    CERN. Geneva

    2008-01-01

    Fusion power as the source of energy on Earth has been the dream of mankind ever since the principles were understood. ITER, the Latin word for “the way”, is the world’s largest Fusion device presently under construction in Cadarache, France. Supported by the People’s Republic of China, the European Atomic Energy Community, India, Japan, the Republic of Korea, the Russian Federation, and the United States of America, an international organization was founded after the signature of the Joint ITER Agreement in October of 2006. The goal is to build a Fusion reactor with a power amplification of 10, a total fusion power of 500 MW or more operating at extended burn times of 400-3000 seconds, with Deuterium and Tritium as its basic fuel. Following a short introduction into fusion science principles, the history of thermo nuclear fusion will be covered. Finally more recent construction projects around the world, their latest achievements and the path to ITER will be described. Technological and scientific c...

  11. Conformal mapping and convergence of Krylov iterations

    Energy Technology Data Exchange (ETDEWEB)

    Driscoll, T.A.; Trefethen, L.N. [Cornell Univ., Ithaca, NY (United States)

    1994-12-31

    Connections between conformal mapping and matrix iterations have been known for many years. The idea underlying these connections is as follows. Suppose the spectrum of a matrix or operator A is contained in a Jordan region E in the complex plane with 0 not an element of E. Let {phi}(z) denote a conformal map of the exterior of E onto the exterior of the unit disk, with {phi}{infinity} = {infinity}. Then 1/{vert_bar}{phi}(0){vert_bar} is an upper bound for the optimal asymptotic convergence factor of any Krylov subspace iteration. This idea can be made precise in various ways, depending on the matrix iterations, on whether A is finite or infinite dimensional, and on what bounds are assumed on the non-normality of A. This paper explores these connections for a variety of matrix examples, making use of a new MATLAB Schwarz-Christoffel Mapping Toolbox developed by the first author. Unlike the earlier Fortran Schwarz-Christoffel package SCPACK, the new toolbox computes exterior as well as interior Schwarz-Christoffel maps, making it easy to experiment with spectra that are not necessarily symmetric about an axis.

  12. Recent ADI iteration analysis and results

    Energy Technology Data Exchange (ETDEWEB)

    Wachspress, E.L.

    1994-12-31

    Some recent ADI iteration analysis and results are discussed. Discovery that the Lyapunov and Sylvester matrix equations are model ADI problems stimulated much research on ADI iteration with complex spectra. The ADI rational Chebyshev analysis parallels the classical linear Chebyshev theory. Two distinct approaches have been applied to these problems. First, parameters which were optimal for real spectra were shown to be nearly optimal for certain families of complex spectra. In the linear case these were spectra bounded by ellipses in the complex plane. In the ADI rational case these were spectra bounded by {open_quotes}elliptic-function regions{close_quotes}. The logarithms of the latter appear like ellipses, and the logarithms of the optimal ADI parameters for these regions are similar to the optimal parameters for linear Chebyshev approximation over superimposed ellipses. W.B. Jordan`s bilinear transformation of real variables to reduce the two-variable problem to one variable was generalized into the complex plane. This was needed for ADI iterative solution of the Sylvester equation.

  13. Iterative solution of the semiconductor device equations

    Energy Technology Data Exchange (ETDEWEB)

    Bova, S.W.; Carey, G.F. [Univ. of Texas, Austin, TX (United States)

    1996-12-31

    Most semiconductor device models can be described by a nonlinear Poisson equation for the electrostatic potential coupled to a system of convection-reaction-diffusion equations for the transport of charge and energy. These equations are typically solved in a decoupled fashion and e.g. Newton`s method is used to obtain the resulting sequences of linear systems. The Poisson problem leads to a symmetric, positive definite system which we solve iteratively using conjugate gradient. The transport equations lead to nonsymmetric, indefinite systems, thereby complicating the selection of an appropriate iterative method. Moreover, their solutions exhibit steep layers and are subject to numerical oscillations and instabilities if standard Galerkin-type discretization strategies are used. In the present study, we use an upwind finite element technique for the transport equations. We also evaluate the performance of different iterative methods for the transport equations and investigate various preconditioners for a few generalized gradient methods. Numerical examples are given for a representative two-dimensional depletion MOSFET.

  14. Magnetic configuration control of ITER plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Albanese, R.; Mattei, M. [Assoc. Euratom-ENEA-CREATE, Univ. Mediterranea RC, Loc. Feo di Vito I-89060, RC (Italy); Portone, A. [EFDA-CSU, Max Planck Institute for Plasmaphysics, Boltzmannstrasse 2, D-85748 Garching (Germany)], E-mail: alfredo.portone@tech.efda.org; Ambrosino, G. [Assoc. Euratom-ENEA-CREATE, University Napoli Federico II, Via Claudio 21, I-80125 Naples (Italy); Artaserse, G. [Assoc. Euratom-ENEA-CREATE, Univ. Mediterranea RC, Loc. Feo di Vito I-89060, RC (Italy); Crisanti, F. [Associazione EURATOM-ENEA sulla Fusione, Frascati, C.P. 65, 00044-Frascati (Italy); De Tommasi, G. [Assoc. Euratom-ENEA-CREATE, University Napoli Federico II, Via Claudio 21, I-80125 Naples (Italy); Fresa, R. [DIFA, University della Basilicata, Contrada Macchia Romana I-85100, PZ (Italy); Sartori, F. [Euratom/UKAEA Fusion Assoc., Culham Science Centre, Abingdon, Oxon OX14 3DB (United Kingdom); Villone, F. [Assoc. Euratom-ENEA-CREATE, University Cassino, Via Di Biasio 43, I-03043 Cassino (Italy)

    2007-10-15

    The aim of this paper is to present some new tools used to review the capability of the ITER Poloidal Field (PF) system in controlling the broad range of plasma configurations presently forecasted during ITER operation. The attention is focused on the axi-symmetric aspects of plasma magnetic configuration control since they pose the greatest challenges in terms of control power and they have the largest impact on machine capital cost. Some preliminary results obtained during ongoing activities in collaboration between ENEA/CREATE and EFDA are presented. The paper is divided in two main parts devoted, respectively, to the presentation of a procedure for the PF current optimisation during the scenario, and of a software environment for the study of the PF system capabilities using the plasma linearized response. The proposed PF current optimisation procedure is then used to assess Scenario 2 design, also taking into account the presence of axisymmetric eddy currents and possible variations of poloidal beta and internal inductance. The numerical linear model based tool derived from the JET oriented eXtreme Shape Controller (XSC) tools is finally used to obtain results on the strike point sweeping in ITER.

  15. submitter Starting Manufacture of the ITER Central Solenoid

    CERN Document Server

    Libeyre, P; Dolgetta, N; Gaxiola, E; Jong, C; Lyraud, C; Mitchell, N; Journeaux, J Y; Vollmann, T; Evans, D; Sgobba, S; Langeslag, S; Reiersen, W; Martovetsky, N; Everitt, D; Hatfield, D; Rosenblad, P; Litherland, S; Freudenberg, K; Myatt, L; Smith, J; Brazelton, C; Abbott, R; Daubert, J; Rackers, K; Nentwich, T

    2016-01-01

    The central solenoid (CS) is a key component of the ITER magnet system to provide the magnetic flux swing required to drive induced plasma current up to 15 MA. The manufacture of its different subcomponents has now started, following completion of the design analyses and achievement of the qualification of the manufacturing procedures. A comprehensive set of analyses has been produced to demonstrate that the CS final design meets all requirements. This includes in particular structural analyses carried out with different finite-element models and addressing normal and fault conditions. Following the Final Design Review, held in November 2013, and the subsequent design modifications, the analyses were updated for consistency with the final design details and provide evidence that the Magnet Structural Design Criteria are fully met. Before starting any manufacturing activity of a CS component, a corresponding dedicated qualification program has been carried out. This includes manufacture of mockups using the re...

  16. Specification of asymmetric VDE loads of the ITER tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Bachmann, C., E-mail: christian.bachmann@iter.org [ITER Organization CS90 046, 13067St. Paul lez Durance, Cedex (France); Sugihara, M.; Roccella, R.; Sannazzaro, G.; Gribov, Y. [ITER Organization CS90 046, 13067St. Paul lez Durance, Cedex (France); Riccardo, V.; Hender, T.C.; Gerasimov, S.N. [EURATOM/CCFE Fusion Association, Culham Science Centre, Abingdon OX14 3DB (United Kingdom); Pautasso, G. [Max Planck Institute for Plasma Physics, D-85748 Garching (Germany); Belov, A.; Lamzin, E. [D.V. Efremov Institute, Scientific Technical Centre ' Sintez' (Russian Federation); Roccella, M. [L. T. Calcoli, 23087 Merate, Lecco (Italy)

    2011-10-15

    During asymmetric vertical displacement events (AVDEs) associated with the kink mode of the plasma two asymmetry phenomena were observed in existing tokamaks, in particular in JET . The related halo currents flowing in the passive structure were identified as the cause of asymmetric EM loads on tokamak components. The first phenomenon is a toroidal peak of the poloidal halo current that flows in the passive structure. The second phenomenon is that the toroidal plasma current is not uniform toroidally, so a toroidally non-uniform current flows in the vessel . The specification of the expected characteristics of both phenomena as well as of the consequent asymmetric loads in ITER are summarized here. The related loads are specified for likely, unlikely and extremely unlikely AVDEs.

  17. Iterative exponential growth of stereo- and sequence-controlled polymers.

    Science.gov (United States)

    Barnes, Jonathan C; Ehrlich, Deborah J C; Gao, Angela X; Leibfarth, Frank A; Jiang, Yivan; Zhou, Erica; Jamison, Timothy F; Johnson, Jeremiah A

    2015-10-01

    Chemists have long sought sequence-controlled synthetic polymers that mimic nature's biopolymers, but a practical synthetic route that enables absolute control over polymer sequence and structure remains a key challenge. Here, we report an iterative exponential growth plus side-chain functionalization (IEG+) strategy that begins with enantiopure epoxides and facilitates the efficient synthesis of a family of uniform >3 kDa macromolecules of varying sequence and stereoconfiguration that are coupled to produce unimolecular polymers (>6 kDa) with sequences and structures that cannot be obtained using traditional polymerization techniques. Selective side-chain deprotection of three hexadecamers is also demonstrated, which imbues each compound with the ability to dissolve in water. We anticipate that these new macromolecules and the general IEG+ strategy will find broad application as a versatile platform for the scalable synthesis of sequence-controlled polymers.

  18. Cryogenic Properties of Inorganic Insulation Materials for ITER Magnets: A Review

    Energy Technology Data Exchange (ETDEWEB)

    Simon, N.J.

    1994-12-01

    Results of a literature search on the cryogenic properties of candidate inorganic insulators for the ITER TF magnets are reported. The materials investigated include: Al{sub 2}O{sub 3}, AlN, MgO, porcelain, SiO{sub 2}, MgAl{sub 2}O{sub 4}, ZrO{sub 2}, and mica. A graphical presentation is given of mechanical, elastic, electrical, and thermal properties between 4 and 300 K. A companion report reviews the low temperature irradiation resistance of these materials.

  19. Ideal MHD Stability of ITER Steady State Scenarios with ITBs

    Energy Technology Data Exchange (ETDEWEB)

    F.M. Poli, C.E. Kessel, S. Jardin, J. Manickam, M. Chance, J. Chen

    2011-07-27

    One of ITER goals is to demonstrate feasibility of continuous operations using non-inductive current drive. Two main candidates have been identified for advanced operations: the long duration, high neutron fluency hybrid scenario and the steady state scenario, both operating at a plasma current lower than the reference ELMy scenario [1][2] to minimize the required current drive. The steady state scenario targets plasmas with current 7-10 MA in the flat-top, 50% of which will be provided by the self-generated, pressure-driven bootstrap current. It has been estimated that, in order to obtain a fusion gain Q > 5 at a current of 9 MA, it should be ΒN > 2.5 and H > 1.5 [3]. This implies the presence of an Internal Transport Barrier (ITB). This work discusses how the stability of steady state scenarios with ITBs is affected by the external heating sources and by perturbations of the equilibrium profiles.

  20. Thermal-hydraulics of LLCB TBM under different ITER operational conditions

    Energy Technology Data Exchange (ETDEWEB)

    Chaudhuri, Paritosh, E-mail: paritc@gmail.com; Ranjithkumar, S.; Sharma, Deepak; Danani, Chandan; Kumar, E. Rajendra

    2016-11-01

    Highlights: • Thermal analysis of LLCB TBM has been performed for different ITER operations during normal and power excursion scenarios. • It is observed that in all ITER operations, the temperatures in all components of LLCB TBM are well within the limits. • The maximum temperature of CB-1 in steady state is 920 °C, which is 72% of the maximum temperature obtained in ITER pulse. - Abstract: Lead–lithium cooled ceramic breeder (LLCB) TBM is the Indian DEMO relevant blanket module, which will be tested in one-half of a designated ITER port from day 1 operation of ITER. LLCB TBM will be tested in various ITER operational phases. Different TBM may be tested corresponding to the four different phases of plasma operation. The paper present a review of thermal analyses based on the various heat loads on the LLCB TBM obtained from neutronics calculations to confirm heat removal and structural integrity under different ITER operational conditions. This includes the normal plasma operation, fusion power excursions, surface heat flux due to MARFES, disruption heat loads during thermal and current quench etc., in inductive and non-inductive plasma operations. Transient events, like plasma disruption, vertical displacement events (VDEs) and edge localized modes (ELMs) deliver considerable heat flux (high power densities) for short durations onto the first wall of TBM. Detailed thermal-hydraulic simulation studies have been performed using ANSYS. These analyses, therefore, will provide important information about the temperature distribution in different materials used in TBM and their temperature-time histories.

  1. A simulation environment for ITER PCS development

    Energy Technology Data Exchange (ETDEWEB)

    Walker, M.L., E-mail: walker@fusion.gat.com [General Atomics, P.O. Box 85608, San Diego, CA 92186-5608 (United States); Ambrosino, G.; De Tommasi, G. [CREATE/Università di Napoli Federcico II, Napoli (Italy); Humphreys, D.A. [General Atomics, P.O. Box 85608, San Diego, CA 92186-5608 (United States); Mattei, M. [Seconda Università di Napoli, Napoli (Italy); Neu, G.; Raupp, G.; Treutterer, W. [Max-Planck-Institut fuer Plasmaphysik, EURATOM Association, 85748 Garching (Germany); Winter, A. [ITER Organization, Route de Vinon-sur-Verdon, 13115 St. Paul-lez-Durance (France)

    2014-05-15

    Highlights: • Describes task to develop simulation tool to aid development/testing of ITER PCS. • Requirements and use cases and preliminary architecture have been delivered. • Detailed design is now being developed. • Provides overview of use cases and requirements. • Provides overview of architecture and status of development. - Abstract: A simulation environment known as the Plasma Control System Simulation Platform (PCSSP), specifically designed to support development of the ITER Plasma Control System (PCS), is currently under construction by an international team encompassing a cross-section of expertise in simulation and exception handling for plasma control. The proposed design addresses the challenging requirements of supporting the PCS design. This paper provides an overview of the PCSSP project and a discussion of some of the major features of its design. Plasma control for the ITER tokamak will be significantly more challenging than for existing fusion devices. An order of magnitude greater performance (e.g. [1,2]) is needed for some types of control, which together with limited actuator authority, implies that optimized individual controllers and nonlinear saturation logic are required. At the same time, consequences of control failure are significantly more severe, which implies a conflicting requirement for robust control. It also implies a requirement for comprehensive and robust exception handling. Coordinated control of multiple competing objectives with significant interactions, together with many shared uses of actuators to control multiple variables, implies that highly integrated control logic and shared actuator management will be required. It remains a challenge for the integrated technologies to simultaneously address these multiple and often competing requirements to be demonstrated on existing fusion devices and adapted for ITER in time to support its operational schedule. We describe ways in which the PCSSP will help address

  2. Convergence of iterative image reconstruction algorithms for Digital Breast Tomosynthesis

    DEFF Research Database (Denmark)

    Sidky, Emil; Jørgensen, Jakob Heide; Pan, Xiaochuan

    2012-01-01

    solutions can aid in iterative image reconstruction algorithm design. This issue is particularly acute for iterative image reconstruction in Digital Breast Tomosynthesis (DBT), where the corresponding data model IS particularly poorly conditioned. The impact of this poor conditioning is that iterative......Most iterative image reconstruction algorithms are based on some form of optimization, such as minimization of a data-fidelity term plus an image regularizing penalty term. While achieving the solution of these optimization problems may not directly be clinically relevant, accurate optimization....... Math. Imag. Vol. 40, pgs 120-145) and apply it to iterative image reconstruction in DBT....

  3. The JET ITER-like wall experiment: First results and lessons for ITER

    Energy Technology Data Exchange (ETDEWEB)

    Horton, Lorne, E-mail: Lorne.Horton@jet.efda.org [EFDA-CSU Culham, Culham Science Centre, Abingdon, OX14 3DB (United Kingdom); European Commission, B-1049 Brussels (Belgium)

    2013-10-15

    Highlights: ► JET has recently completed the installation of an ITER-like wall. ► Important operational aspects have changed with the new wall. ► Initial experiments have confirmed the expected low fuel retention. ► Disruption dynamics have change dramatically. ► Development of wall-compatible, ITER-relevant regimes of operation has begun. -- Abstract: The JET programme is strongly focused on preparations for ITER construction and exploitation. To this end, a major programme of machine enhancements has recently been completed, including a new ITER-like wall, in which the plasma-facing armour in the main vacuum chamber is beryllium while that in the divertor is tungsten—the same combination of plasma-facing materials foreseen for ITER. The goal of the initial experimental campaigns is to fully characterise operation with the new wall, concentrating in particular on plasma-material interactions, and to make direct comparisons of plasma performance with the previous, carbon wall. This is being done in a progressive manner, with the input power and plasma performance being increased in combination with the commissioning of a comprehensive new real-time protection system. Progress achieved during the first set of experimental campaigns with the new wall, which took place from September 2011 to July 2012, is reported.

  4. Evaluation of ITER MSE Viewing Optics

    Energy Technology Data Exchange (ETDEWEB)

    Allen, S; Lerner, S; Morris, K; Jayakumar, J; Holcomb, C; Makowski, M; Latkowski, J; Chipman, R

    2007-03-26

    The Motional Stark Effect (MSE) diagnostic on ITER determines the local plasma current density by measuring the polarization angle of light resulting from the interaction of a high energy neutral heating beam and the tokamak plasma. This light signal has to be transmitted from the edge and core of the plasma to a polarization analyzer located in the port plug. The optical system should either preserve the polarization information, or it should be possible to reliably calibrate any changes induced by the optics. This LLNL Work for Others project for the US ITER Project Office (USIPO) is focused on the design of the viewing optics for both the edge and core MSE systems. Several design constraints were considered, including: image quality, lack of polarization aberrations, ease of construction and cost of mirrors, neutron shielding, and geometric layout in the equatorial port plugs. The edge MSE optics are located in ITER equatorial port 3 and view Heating Beam 5, and the core system is located in equatorial port 1 viewing heating beam 4. The current work is an extension of previous preliminary design work completed by the ITER central team (ITER resources were not available to complete a detailed optimization of this system, and then the MSE was assigned to the US). The optimization of the optical systems at this level was done with the ZEMAX optical ray tracing code. The final LLNL designs decreased the ''blur'' in the optical system by nearly an order of magnitude, and the polarization blur was reduced by a factor of 3. The mirror sizes were reduced with an estimated cost savings of a factor of 3. The throughput of the system was greater than or equal to the previous ITER design. It was found that optical ray tracing was necessary to accurately measure the throughput. Metal mirrors, while they can introduce polarization aberrations, were used close to the plasma because of the anticipated high heat, particle, and neutron loads. These mirrors

  5. Design of the RF ion source for the ITER NBI

    Energy Technology Data Exchange (ETDEWEB)

    Marcuzzi, D. [Consorzio RFX, Euratom-ENEA Association, Corso Stati Uniti 4, I-35127 Padova (Italy)], E-mail: diego.marcuzzi@igi.cnr.it; Agostinetti, P.; Dalla Palma, M. [Consorzio RFX, Euratom-ENEA Association, Corso Stati Uniti 4, I-35127 Padova (Italy); Falter, H.D.; Heinemann, B.; Riedl, R. [Max-Planck-Institut fuer Plasmaphysik, D-85748 Garching (Germany)

    2007-10-15

    A radio frequency (RF) driven negative ion source has been designed for the ITER neutral beam injectors, as an alternative to the traditional arc driven solution. The main advantage of this technology is to avoid the presence of the filaments, that require periodic maintenance and consequently frequent shutdowns. The requirements for the ion source of the ITER NBI are to provide a uniform flux of D{sup -}/H{sup -} to the plasma grid of the accelerator that will result in a beam current of 40 A at 1 MeV. The present specification is for a filling pressure of 0.3 Pa. The ion source needs to provide 20/28 mA/cm{sup 2} D{sup -}/H{sup -} current density across the 0.58 m x 1.54 m aperture array for 3600 s. The source, consisting of a main chamber facing the plasma grid, of eight RF drivers and the auxiliary systems for power transfer, cooling and diagnostic purposes, is housed in the same quasi-cylindrical structure that supports the arc driven solution. Specific electric and hydraulic circuits have been designed and verified. In the paper the analyses performed for the design of the components are presented in detail.

  6. Iterative solution of large sparse systems of equations

    CERN Document Server

    Hackbusch, Wolfgang

    2016-01-01

    In the second edition of this classic monograph, complete with four new chapters and updated references, readers will now have access to content describing and analysing classical and modern methods with emphasis on the algebraic structure of linear iteration, which is usually ignored in other literature. The necessary amount of work increases dramatically with the size of systems, so one has to search for algorithms that most efficiently and accurately solve systems of, e.g., several million equations. The choice of algorithms depends on the special properties the matrices in practice have. An important class of large systems arises from the discretization of partial differential equations. In this case, the matrices are sparse (i.e., they contain mostly zeroes) and well-suited to iterative algorithms. The first edition of this book grew out of a series of lectures given by the author at the Christian-Albrecht University of Kiel to students of mathematics. The second edition includes quite novel approaches.

  7. Testability of AND-EXOR Based Iterative Logic Arrays

    CERN Document Server

    Chakraborty, Avik

    2008-01-01

    Iterative Logic Arrays (ILAs) are ideal as VLSI sub-systems because of their regular structure and its close resemblance with FPGAs (Field Programmable Gate Arrays). AND-EXOR based circuits are of interest in the design of very low power circuits where energy loss implied by high frequency switching is of much consideration. This paper examines the testability of AND-EXOR based Iterative Logic Arrays (ILAs). For certain ILAs it is possible to find a test set whose size remains constant irrespective of the size of the ILA, while for others it varies with array size. Former type of ILAs is known as Constant-Testable (C-Testable). It has been shown that AND-EXOR based Logic Arrays are C-Testable and size of test set is equal to number of entries in cell truth table. The test generation problem has been shown to be related to certain properties of cycles in a set of graphs derived from cell truth table. By careful analysis of these cycles an efficient test generation technique that can be easily converted to an A...

  8. Iterative truncated arithmetic mean filter and its properties.

    Science.gov (United States)

    Jiang, Xudong

    2012-04-01

    The arithmetic mean and the order statistical median are two fundamental operations in signal and image processing. They have their own merits and limitations in noise attenuation and image structure preservation. This paper proposes an iterative algorithm that truncates the extreme values of samples in the filter window to a dynamic threshold. The resulting nonlinear filter shows some merits of both the fundamental operations. Some dynamic truncation thresholds are proposed that guarantee the filter output, starting from the mean, to approach the median of the input samples. As a by-product, this paper unveils some statistics of a finite data set as the upper bounds of the deviation of the median from the mean. Some stopping criteria are suggested to facilitate edge preservation and noise attenuation for both the long- and short-tailed distributions. Although the proposed iterative truncated mean (ITM) algorithm is not aimed at the median, it offers a way to estimate the median by simple arithmetic computing. Some properties of the ITM filters are analyzed and experimentally verified on synthetic data and real images.

  9. Fusion Reactor and Fusion Reactor Materials:Concept Design of the ITER Test Blanket Modules

    Institute of Scientific and Technical Information of China (English)

    HUANGJinhua; LIZaixing; ZHUYukun; HUGang

    2003-01-01

    Performances required: prospect to be adopted in DEMO. Shielding for V.V. and TFC in ITER. Design principles: the peak temperature and stress should not exceed technical limits. The structure of test blanket modules (TBM) should be simple for easy fabrication, and TBM should be robust for reliability.

  10. Net Operations (Ⅱ)——The Iterated Addition Operation of Petri Nets

    Institute of Scientific and Technical Information of China (English)

    蒋昌俊

    1995-01-01

    This paper presents the iterated addition operation of Petri nets and discusses its application in analysis and synthesis of cycle type systems and star type systems.A group of necessary and sufficient conditions for analysis of structural properties is obtained.In addition sufficient conditions for general systems are obtained.

  11. Review of past experiments at the FELIX facility and future plans for ITER applications

    Energy Technology Data Exchange (ETDEWEB)

    Hua, T.Q.; Turner, L.R.

    1993-10-01

    FELIX is an experimental test facility at Argonne National Laboratory (ANL) for the study of electromagnetic effects in first wall, blanket, shield systems of fusion reactors. From 1983 to 1986 five major test series, including static and dynamic tests, were conducted and are reviewed in this paper. The dynamic tests demonstrated an important coupling effect between eddy currents and motion in a conducting structure. Recently the US has proposed to the ITER Joint Central Team to use FELIX for testing mock-up components to study electromagnetic effects encountered during plasma disruptions and other off-normal events. The near and long term plans for ITER applications are discussed.

  12. Iterative Signal Processing for Blind Code Phase Acquisition of CDMA 1x Signals for Radio Spectrum Monitoring

    Directory of Open Access Journals (Sweden)

    Ron Kerr

    2010-01-01

    Full Text Available This paper addresses the problem of recovering the code phase of the composite spreading sequence for a CDMA 1x signal transmitted from a handset, without the benefit of a priori information from the system. The spreading code is required for the radio spectrum monitoring system for signal detection and measurements rather than for communications. The structure of the CDMA 1x signal is exploited by processing sequential pairs of received samples to form a single soft sample for each pair. The approach models the combination of the long-code generator and the two short-code generators, along with the pair-wise processing, by a single linear system over GF(2, with the initial states of the long- and short-code generators forming the input vector. Consequently, a vector of the pair-wise soft samples can be treated as a noisy received codeword that is decoded using iterative soft-in decoding techniques. If the decoder yields the correct candidate “codeword,” the original states of the code generators can be computed. This approach does not require direct access to the transmitted spreading sequence but can be applied to the data modulated signal. Simulation results provide performance estimates of the method with noise, Rayleigh fading, and co-channel interference.

  13. Nuclear safety in EU candidate countries

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-10-01

    Nuclear safety in the candidate countries to the European Union is a major issue that needs to be addressed in the framework of the enlargement process. Therefore WENRA members considered it was their duty to offer their technical assistance to their Governments and the European Union Institutions. They decided to express their collective opinion on nuclear safety in those candidate countries having at least one nuclear power plant: Bulgaria, the Czech Republic, Hungary, Lithuania, Romania, Slovakia and Slovenia. The report is structured as follows: A foreword including background information, structure of the report and the methodology used, General conclusions of WENRA members reflecting their collective opinion, For each candidate country, an executive summary, a chapter on the status of the regulatory regime and regulatory body, and a chapter on the nuclear power plant safety status. Two annexes are added to address the generic safety characteristics and safety issues for RBMK and VVER plants. The report does not cover radiation protection and decommissioning issues, while safety aspects of spent fuel and radioactive waste management are only covered as regards on-site provisions. In order to produce this report, WENRA used different means: For the chapters on the regulatory regimes and regulatory bodies, experts from WENRA did the work. For the chapters on nuclear power plant safety status, experts from WENRA and from French and German technical support organisations did the work. Taking into account the contents of these chapters, WENRA has formulated its general conclusions in this report.

  14. Status of the 1 MeV Accelerator Design for ITER NBI

    Science.gov (United States)

    Kuriyama, M.; Boilson, D.; Hemsworth, R.; Svensson, L.; Graceffa, J.; Schunke, B.; Decamps, H.; Tanaka, M.; Bonicelli, T.; Masiello, A.; Bigi, M.; Chitarin, G.; Luchetta, A.; Marcuzzi, D.; Pasqualotto, R.; Pomaro, N.; Serianni, G.; Sonato, P.; Toigo, V.; Zaccaria, P.; Kraus, W.; Franzen, P.; Heinemann, B.; Inoue, T.; Watanabe, K.; Kashiwagi, M.; Taniguchi, M.; Tobari, H.; De Esch, H.

    2011-09-01

    The beam source of neutral beam heating/current drive system for ITER is needed to accelerate the negative ion beam of 40A with D- at 1 MeV for 3600 sec. In order to realize the beam source, design and R&D works are being developed in many institutions under the coordination of ITER organization. The development of the key issues of the ion source including source plasma uniformity, suppression of co-extracted electron in D beam operation and also after the long beam duration time of over a few 100 sec, is progressed mainly in IPP with the facilities of BATMAN, MANITU and RADI. In the near future, ELISE, that will be tested the half size of the ITER ion source, will start the operation in 2011, and then SPIDER, which demonstrates negative ion production and extraction with the same size and same structure as the ITER ion source, will start the operation in 2014 as part of the NBTF. The development of the accelerator is progressed mainly in JAEA with the MeV test facility, and also the computer simulation of beam optics also developed in JAEA, CEA and RFX. The full ITER heating and current drive beam performance will be demonstrated in MITICA, which will start operation in 2016 as part of the NBTF.

  15. Iterative Neighbour-Information Gathering for Ranking Nodes in Complex Networks

    Science.gov (United States)

    Xu, Shuang; Wang, Pei; Lü, Jinhu

    2017-01-01

    Designing node influence ranking algorithms can provide insights into network dynamics, functions and structures. Increasingly evidences reveal that node’s spreading ability largely depends on its neighbours. We introduce an iterative neighbourinformation gathering (Ing) process with three parameters, including a transformation matrix, a priori information and an iteration time. The Ing process iteratively combines priori information from neighbours via the transformation matrix, and iteratively assigns an Ing score to each node to evaluate its influence. The algorithm appropriates for any types of networks, and includes some traditional centralities as special cases, such as degree, semi-local, LeaderRank. The Ing process converges in strongly connected networks with speed relying on the first two largest eigenvalues of the transformation matrix. Interestingly, the eigenvector centrality corresponds to a limit case of the algorithm. By comparing with eight renowned centralities, simulations of susceptible-infected-removed (SIR) model on real-world networks reveal that the Ing can offer more exact rankings, even without a priori information. We also observe that an optimal iteration time is always in existence to realize best characterizing of node influence. The proposed algorithms bridge the gaps among some existing measures, and may have potential applications in infectious disease control, designing of optimal information spreading strategies. PMID:28117424

  16. F4E studies for the electromagnetic analysis of ITER components

    Energy Technology Data Exchange (ETDEWEB)

    Testoni, P., E-mail: pietro.testoni@f4e.europa.eu [Fusion for Energy, Torres Diagonal Litoral B3, c/ Josep Plá n.2, Barcelona (Spain); Cau, F.; Portone, A. [Fusion for Energy, Torres Diagonal Litoral B3, c/ Josep Plá n.2, Barcelona (Spain); Albanese, R. [Associazione EURATOM/ENEA/CREATE, DIETI, Università Federico II di Napoli, Napoli (Italy); Juirao, J. [Numerical Analysis TEChnologies S.L. (NATEC), c/ Marqués de San Esteban, 52 Entlo D Gijón (Spain)

    2014-10-15

    Highlights: • Several ITER components have been analyzed from the electromagnetic point of view. • Categorization of DINA load cases is described. • VDEs, MDs and MFD have been studied. • Integral values of forces and moments components versus time have been computed for all the ITER components under study. - Abstract: Fusion for Energy (F4E) is involved in a relevant number of activities in the area of electromagnetic analysis in support of ITER general design and EU in-kind procurement. In particular several ITER components (vacuum vessel, blanket shield modules and first wall panels, test blanket modules, ICRH antenna) are being analyzed from the electromagnetic point of view. In this paper we give an updated description of our main activities, highlighting the main assumptions, objectives, results and conclusions. The plasma instabilities we consider, typically disruptions and VDEs, can be both toroidally symmetric and asymmetric. This implies that, depending on the specific component and loading conditions, FE models we use span from a sector of 10 up to 360° of the ITER machine. The techniques for simulating the electromagnetic phenomena involved in a disruption and the postprocessing of the results to obtain the loads acting on the structures are described. Finally we summarize the typical loads applied to different components and give a critical view of the results.

  17. SAGE based iterative receiver for joint synchronization and channel estimation in uplink MIMO-OFDMA systems

    Institute of Scientific and Technical Information of China (English)

    JIANG Zheng; QIN Xiao-fang; ZHANG Xin; CHANG Yong-yu

    2008-01-01

    A new Turbo iterative receiver structure is proposed for the uplink multiple-input multiple-output orthogonal frequency division multiple access (MIMO-OFDMA) systems. The space-alternating generalized expectation-maximization (SAGE) algorithm is naturally embedded in the framework of iterative receiver to perform synchronization and detection using the Turbo detector outputs. In each iteration, the expectation step intends to remove the multiple access interference (MAI) caused by other asynchronous users, and the maximization step is utilized to estimate the required parameters (i.e., timing offset, carrier frequency offset, channel state information, etc.) sequentially for each user. Simulation results show that the proposed algorithm can approach the performance of ideal receiver closely, while the processing complexity is rather lower than the conventional detectors.

  18. Comparison of iterative solvers for electromagnetic analysis of plasmonic nanostructures using multiple surface integral equation formulations

    CERN Document Server

    Gomez-Sousa, Hipolito; Martinez-Lorenzo, Jose Angel

    2015-01-01

    The electromagnetic behavior of plasmonic structures can be predicted after discretizing and solving a linear system of equations, derived from a continuous surface integral equation (SIE) and the appropriate boundary conditions, using a method of moments (MoM) methodology. In realistic large-scale optical problems, a direct inversion of the SIE-MoM matrix cannot be performed due to its large size, and an iterative solver must be used instead. This paper investigates the performance of four iterative solvers (GMRES, TFQMR, CGS, and BICGSTAB) for five different SIE-MoM formulations (PMCHWT, JMCFIE, CTF, CNF, and MNMF). Moreover, under this plasmonic context, a set of suggested guidelines are provided to choose a suitable SIE formulation and iterative solver depending on the desired simulation error and available runtime resources.

  19. BSIRT: a block-iterative SIRT parallel algorithm using curvilinear projection model.

    Science.gov (United States)

    Zhang, Fa; Zhang, Jingrong; Lawrence, Albert; Ren, Fei; Wang, Xuan; Liu, Zhiyong; Wan, Xiaohua

    2015-03-01

    Large-field high-resolution electron tomography enables visualizing detailed mechanisms under global structure. As field enlarges, the distortions of reconstruction and processing time become more critical. Using the curvilinear projection model can improve the quality of large-field ET reconstruction, but its computational complexity further exacerbates the processing time. Moreover, there is no parallel strategy on GPU for iterative reconstruction method with curvilinear projection. Here we propose a new Block-iterative SIRT parallel algorithm with the curvilinear projection model (BSIRT) for large-field ET reconstruction, to improve the quality of reconstruction and accelerate the reconstruction process. We also develop some key techniques, including block-iterative method with the curvilinear projection, a scope-based data decomposition method and a page-based data transfer scheme to implement the parallelization of BSIRT on GPU platform. Experimental results show that BSIRT can improve the reconstruction quality as well as the speed of the reconstruction process.

  20. Homotopy Iteration Algorithm for Crack Parameters Identification with Composite Element Method

    Directory of Open Access Journals (Sweden)

    Ling Huang

    2013-01-01

    Full Text Available An approach based on homotopy iteration algorithm is proposed to identify the crack parameters in beam structures. In the forward problem, a fully open crack model with the composite element method is employed for the vibration analysis. The dynamic responses of the cracked beam in time domain are obtained from the Newmark direct integration method. In the inverse analysis, an identification approach based on homotopy iteration algorithm is studied to identify the location and the depth of a cracked beam. The identification equation is derived by minimizing the error between the calculated acceleration response and the simulated measured one. Newton iterative method with the homotopy equation is employed to track the correct path and improve the convergence of the crack parameters. Two numerical examples are conducted to illustrate the correctness and efficiency of the proposed method. And the effects of the influencing parameters, such as measurement time duration, measurement points, division of the homotopy parameter and measurement noise, are studied.