isolated injection source: Topics by WorldWideScience.org

Sample records for isolated injection source

Persulfate injection into a gasoline source zone

Science.gov (United States)

Sra, Kanwartej S.; Thomson, Neil R.; Barker, Jim F.

2013-07-01

One pore volume of unactivated sodium persulfate was delivered into an emplaced gasoline residual source zone at CFB Borden. Concentrations of inorganic species (S2O82 -, SO42 -, Na+, dissolved inorganic carbon (DIC)) and selected gasoline compounds (benzene, toluene, ethylbenzene, xylenes, trimethylbenzenes and naphthalene) were monitored across a transect equipped with 90 multilevel sampling points for > 10 months post-injection. Mass loading (M˙) of compounds constructed from the transect data was used for assessment purposes. Breakthrough of inorganic species was observed when the injection slug crossed the monitoring transect. An increase in M indicated persulfate consumption during oxidation of gasoline compounds or degradation due to the interaction with aquifer materials. M increased by > 100% suggesting some mineralization of gasoline compounds during treatment. Mass loading for all the monitored gasoline compounds reduced by 46 to 86% as the inorganic slug crossed the monitoring transect. The cumulative mass discharge across the monitoring transect was 19 to 58% lower than that expected without persulfate injection. After the inorganic injection slug was flushed from the source zone a partial rebound (40 to 80% of baseline levels) of mass discharge of the monitored gasoline compounds was observed. The ensemble of data collected provides insight into the fate and transport of the injected persulfate solution, and the accompanying treatment of a gasoline the source zone.
Persulfate injection into a gasoline source zone.

Science.gov (United States)

Sra, Kanwartej S; Thomson, Neil R; Barker, Jim F

2013-07-01

One pore volume of unactivated sodium persulfate was delivered into an emplaced gasoline residual source zone at CFB Borden. Concentrations of inorganic species (S2O8(2-), SO4(2-), Na(+), dissolved inorganic carbon (DIC)) and selected gasoline compounds (benzene, toluene, ethylbenzene, xylenes, trimethylbenzenes and naphthalene) were monitored across a transect equipped with 90 multilevel sampling points for >10months post-injection. Mass loading (M˙) of compounds constructed from the transect data was used for assessment purposes. Breakthrough of inorganic species was observed when the injection slug crossed the monitoring transect. An increase in [Formula: see text] indicated persulfate consumption during oxidation of gasoline compounds or degradation due to the interaction with aquifer materials. M˙DIC increased by >100% suggesting some mineralization of gasoline compounds during treatment. Mass loading for all the monitored gasoline compounds reduced by 46 to 86% as the inorganic slug crossed the monitoring transect. The cumulative mass discharge across the monitoring transect was 19 to 58% lower than that expected without persulfate injection. After the inorganic injection slug was flushed from the source zone a partial rebound (40 to 80% of baseline levels) of mass discharge of the monitored gasoline compounds was observed. The ensemble of data collected provides insight into the fate and transport of the injected persulfate solution, and the accompanying treatment of a gasoline the source zone. Copyright © 2013 Elsevier B.V. All rights reserved.
Ion source and injection line for high intensity medical cyclotron

Science.gov (United States)

Jia, XianLu; Guan, Fengping; Yao, Hongjuan; Zhang, TianJue; Yang, Jianjun; Song, Guofang; Ge, Tao; Qin, Jiuchang

2014-02-01

A 14 MeV high intensity compact cyclotron, CYCIAE-14, was built at China Institute of Atomic Energy (CIAE). An injection system based on the external H- ion source was used on CYCIAE-14 so as to provide high intensity beam, while most positron emission tomography cyclotrons adopt internal ion source. A beam intensity of 100 μA/14 MeV was extracted from the cyclotron with a small multi-cusp H- ion source (CIAE-CH-I type) and a short injection line, which the H- ion source of 3 mA/25 keV H- beam with emittance of 0.3π mm mrad and the injection line of with only 1.2 m from the extraction of ion source to the medial plane of the cyclotron. To increase the extracted beam intensity of the cyclotron, a new ion source (CIAE-CH-II type) of 9.1 mA was used, with maximum of 500 μA was achieved from the cyclotron. The design and test results of the ion source and injection line optimized for high intensity acceleration will be given in this paper.
Do Staphylococcus epidermidis Genetic Clusters Predict Isolation Sources?

Science.gov (United States)

Tolo, Isaiah; Thomas, Jonathan C.; Fischer, Rebecca S. B.; Brown, Eric L.; Gray, Barry M.

2016-01-01

Staphylococcus epidermidis is a ubiquitous colonizer of human skin and a common cause of medical device-associated infections. The extent to which the population genetic structure of S. epidermidis distinguishes commensal from pathogenic isolates is unclear. Previously, Bayesian clustering of 437 multilocus sequence types (STs) in the international database revealed a population structure of six genetic clusters (GCs) that may reflect the species' ecology. Here, we first verified the presence of six GCs, including two (GC3 and GC5) with significant admixture, in an updated database of 578 STs. Next, a single nucleotide polymorphism (SNP) assay was developed that accurately assigned 545 (94%) of 578 STs to GCs. Finally, the hypothesis that GCs could distinguish isolation sources was tested by SNP typing and GC assignment of 154 isolates from hospital patients with bacteremia and those with blood culture contaminants and from nonhospital carriage. GC5 was isolated almost exclusively from hospital sources. GC1 and GC6 were isolated from all sources but were overrepresented in isolates from nonhospital and infection sources, respectively. GC2, GC3, and GC4 were relatively rare in this collection. No association was detected between fdh-positive isolates (GC2 and GC4) and nonhospital sources. Using a machine learning algorithm, GCs predicted hospital and nonhospital sources with 80% accuracy and predicted infection and contaminant sources with 45% accuracy, which was comparable to the results seen with a combination of five genetic markers (icaA, IS256, sesD [bhp], mecA, and arginine catabolic mobile element [ACME]). Thus, analysis of population structure with subgenomic data shows the distinction of hospital and nonhospital sources and the near-inseparability of sources within a hospital. PMID:27076664
Heavy Ion Injection Into Synchrotrons, Based On Electron String Ion Sources

CERN Document Server

Donets, E E; Syresin, E M

2004-01-01

A possibility of heavy ions injection into synchrotrons is discussed on the base of two novel ion sources, which are under development JINR during last decade: 1) the electron string ion source (ESIS), which is a modified version of a conventional electron beam ion source (EBIS), working in a reflex mode of operation, and 2) the tubular electron string ion source (TESIS). The Electron String Ion Source "Krion-2" (VBLHE, JINR, Dubna) with an applied confining magnetic field of 3 T was used for injection into the superconducting JINR synchrotron - Nuclotron and during this runs the source provided a high pulse intensity of the highly charged ion beams: Ar16+
Mechanical design of injection line for VEC

International Nuclear Information System (INIS)

Nandi, C.; Bandopadhyay, D.K.; Pal, G.; Sharma, R.N.; Mallik, C.; Chaudhuri, J.; Bhandari, R.K.

2003-01-01

A 14.5 GHz ECR ion source along with its analyzing section was earlier installed at VECC for injecting multiply charged gaseous and metallic ions into the existing K 130 cyclotron. The injection line from this ECR ion source was connected to the vertical section of the existing injection line for integrating it with the K 130 cyclotron. The injection line comprises two solenoid magnets, a steering magnet, and a bending magnet. In between the solenoid magnets a length about 1.5 metres has been provided for future atomic physics experimental applications. Two gate valves are used to isolate this area. For beam diagnostics, two Faraday cups, designed and fabricated in this centre, have been installed
Patients experience of source isolation

DEFF Research Database (Denmark)

Johansen, Kamilla; Pedersen, Didde; Kragbak, Nina

2014-01-01

, Nursing education in Århus, Hedeager 2, 8200 Aarhus N, Denmark. Background: Medical treatment and care of patients with infections may include source isolation of the patient, to avoid spreading of the infection. However, isolation is a potential physiological and psychological stress factor...... of the patients perspectives of being isolated to identify areas of potential interest for developing new caring strategies to minimize the negative side effects of isolation. Methods: Literature was systematically searched in CINAHL, Nursing Reference Center, Social Care Online, SveMed+, The Cochrane Library...... of Care: The patients felt abandoned and forgotten by the nurses, because of fewer visits and time limited communication. This led to emotions such as frustrations, insecurity and neglect. While isolated the patients felt it difficult to achieve contact and have an optimal relation with the nurses...
Injectable barriers for waste isolation

International Nuclear Information System (INIS)

Persoff, P.; Finsterle, S.; Moridis, G.J.; Apps, J.; Pruess, K.; Muller, S.J.

1995-03-01

In this paper the authors report laboratory work and numerical simulation done in support of development and demonstration of injectable barriers formed from either of two fluids: colloidal silica or polysiloxane. Two principal problems addressed here are control of gel time and control of plume emplacement in the vadose zone. Gel time must be controlled so that the viscosity of the barrier fluid remains low long enough to inject the barrier, but increases soon enough to gel the barrier in place. During injection, the viscosity must be low enough to avoid high injection pressures which could uplift or fracture the formation. To test the grout gel time in the soil, the injection pressure was monitored as grouts were injected into sandpacks. When grout is injected into the vadose zone, it slumps under the influence of gravity, and redistributes due to capillary forces as it gels. The authors have developed a new module for the reservoir simulator TOUGH2 to model grout injection into the vadose zone, taking into account the increase of liquid viscosity as a function of gel concentration and time. They have also developed a model to calculate soil properties after complete solidification of the grout. The numerical model has been used to design and analyze laboratory experiments and field pilot tests. The authors present the results of computer simulations of grout injection, redistribution, and solidification
A low loss Faraday isolator for squeezed vacuum injection in Advanced LIGO

Science.gov (United States)

Goetz, Ryan; Tanner, David; Mueller, Guido

2016-03-01

Using conventional interferometry, the strain sensitivity of Advanced LIGO is limited by a quantum noise floor known as the standard quantum limit (SQL). Injecting squeezed vacuum states into the output port of the interferometer allows for detector sensitivities below the SQL at frequencies within a band of observational interest. The effectiveness of squeezing in reducing quantum noise is strongly dependent upon the optical loss in the squeezed path. Thus, to combine the squeezed vacuum state with the interferometer output we require a Faraday isolator with both high power-throughput efficiency and high isolation ratio. A prototype isolator is currently being developed, and we will discuss the design goals and current status.
Plume persistence caused by back diffusion from thin clay layers in a sand aquifer following TCE source-zone hydraulic isolation.

Science.gov (United States)

Parker, Beth L; Chapman, Steven W; Guilbeault, Martin A

2008-11-14

This paper concludes that back diffusion from one or a few thin clayey beds in a sand aquifer can cause contaminant persistence above MCLs in a sand aquifer long after the source zone initially causing the plume is isolated or removed. This conclusion is based on an intensive case study of a TCE contaminated site in Florida, with the processes evaluated using numerical modeling. At this site, the TCE DNAPL zone formed decades ago, and was hydraulically isolated by means of an innovative system performing groundwater extraction, treatment and re-injection. Treated water is re-injected in a row of injection wells situated a short distance downgradient of the extraction wells, creating a clean-water displacement front to efficiently flush the downgradient plume. This scheme avoids the creation of stagnation zones typical of most groundwater pump-and-treat systems, thereby minimizing the time for aquifer flushing and therefore downgradient cleanup. The system began operation in August 2002 and although the performance monitoring shows substantial declines in concentrations, detectable levels of TCE and degradation products persist downgradient of the re-injection wells, long after the TCE should have disappeared based on calculations assuming a nearly homogenous sand aquifer. Three hypotheses were assessed for this plume persistence: 1) incomplete source-zone capture, 2) DNAPL occurrence downgradient of the re-injection wells, and 3) back diffusion from one or more thin clay beds in the aquifer. After careful consideration, the first two hypotheses were eliminated, leaving back diffusion as the only plausible hypothesis, supported by detailed measurements of VOC concentrations within and near the clay beds and also by numerical model simulations that closely represent the field site hydrogeologic conditions. The model was also used to simulate a more generalized, hypothetical situation where more thin clayey beds occur in a sand aquifer with an underlying aquitard
Progress in ISOL target-ion source systems

Energy Technology Data Exchange (ETDEWEB)

Koester, U. [Institut Laue Langevin, 6 Rue Jules Horowitz, F-38042 Grenoble Cedex 9 (France); ISOLDE, CERN, CH-1211 Geneve 23 (Switzerland)], E-mail: koester@ill.fr; Arndt, O. [HGF VISTARS and Institut fuer Kernchemie, Johannes-Gutenberg Universitaet Mainz, D-55128 Mainz (Germany); Bouquerel, E.; Fedoseyev, V.N. [ISOLDE, CERN, CH-1211 Geneve 23 (Switzerland); Franberg, H. [ISOLDE, CERN, CH-1211 Geneve 23 (Switzerland); Laboratory for Radio- and Environmental Chemistry, Paul Scherrer Institut, CH-5232 Villigen PSI (Switzerland); Joinet, A. [ISOLDE, CERN, CH-1211 Geneve 23 (Switzerland); Centre d' Etude Spatiale des Rayonnements, 9 Av. du Colonel Roche, F-31028 Toulouse Cedex 4 (France); Jost, C. [HGF VISTARS and Institut fuer Kernchemie, Johannes-Gutenberg Universitaet Mainz, D-55128 Mainz (Germany); Kerkines, I.S.K. [Laboratory of Physical Chemistry, National and Kapodistrian University of Athens, Department of Chemistry, Zografou 157 71, GR (Greece); Cherry L. Emerson Center for Scientific Computation and Department of Chemistry, Emory University, Atlanta, GA 30322 (United States); Kirchner, R. [Gesellschaft fuer Schwerionenforschung, Planckstr. 1, D-64291 Darmstadt (Germany)

2008-10-15

The heart of every ISOL (isotope separation on-line) facility is its target and ion source system. Its efficiency, selectivity and rapidity is decisive for the production of intense and pure ion beams of short-lived isotopes. Recent progress in ISOL target and ion source technology is discussed at the examples of radioactive ion beams of exotic zinc and tin isotopes that were purified by isothermal chromatography and molecular sideband separation respectively. An outlook is given to which other elements these purification methods are applicable.
Progress in ISOL target-ion source systems

International Nuclear Information System (INIS)

Koester, U.; Arndt, O.; Bouquerel, E.; Fedoseyev, V.N.; Franberg, H.; Joinet, A.; Jost, C.; Kerkines, I.S.K.; Kirchner, R.

2008-01-01

The heart of every ISOL (isotope separation on-line) facility is its target and ion source system. Its efficiency, selectivity and rapidity is decisive for the production of intense and pure ion beams of short-lived isotopes. Recent progress in ISOL target and ion source technology is discussed at the examples of radioactive ion beams of exotic zinc and tin isotopes that were purified by isothermal chromatography and molecular sideband separation respectively. An outlook is given to which other elements these purification methods are applicable.
Patient experience of source isolation: lessons for clinical practice.

Science.gov (United States)

Barratt, Ruth Linda; Shaban, Ramon; Moyle, Wendy

2011-10-01

Methicillin-resistant Staphylococcus aureus (MRSA) is now the leading antimicrobial-resistant organism of concern to clinicians worldwide. Preventing and controlling the increase and spread of MRSA within the health-care environment is therefore an important function of the infection control team. The prevention and control of MRSA requires strict use of both Standard and Additional Precautions, which include good hand hygiene practices, judicious antimicrobial prescribing, and source isolation. While few would dispute the need for these precautions for preventing the spread of MRSA and other infections, their use may result in adverse physical and psychological effects for the patient. In an age of quality and safety of health care, ensuring infection control practice such as source isolation and contact precautions adhere to fundamental human rights is paramount. This paper presents a review of the literature on the patient experience of source isolation for MRSA or other infectious diseases. The review yielded five major interconnected themes: (1) psychological effects of isolation; (2) coping with isolation; (3) social isolation; (4) communication and information provision; and (5) physical environment and quality of care. It found that the experience of isolation by patients has both negative and positive elements. Isolation may result in detrimental psychological effects including anxiety, stress and depression, but may also result in the patient receiving less or substandard care. However, patients may also benefit from the quietness and privacy of single rooms. Nurses and other healthcare workers must look for ways to improve the experience of isolation and contact precautions of patients in source isolation. Opportunities exist in particular in improving the environment and the patient's self-control of the situation and in providing adequate information.
Development of the ion source for PDX neutral beam injection

International Nuclear Information System (INIS)

Menon, M.M.; Tsai, C.C.; Gardner, W.L.; Barber, G.C.; Haselton, H.H.; Ponte, N.S.; Ryan, P.M.; Schechter, D.E.; Stirling, W.L.; Whealton, J.H.

1979-01-01

The paper describes the development of the ion source for neutral beam injection heating of PDX plasma. After a brief description of the plasma generator, the performance characteristics of the source, with different types of grids, are described. Based on test stand results it is concluded that at least two different versions of the source should be able to meet and even exceed the neutral power and energy requirements expected out of PDX injectors
Tokamak startup using point-source dc helicity injection.

Science.gov (United States)

Battaglia, D J; Bongard, M W; Fonck, R J; Redd, A J; Sontag, A C

2009-06-05

Startup of a 0.1 MA tokamak plasma is demonstrated on the ultralow aspect ratio Pegasus Toroidal Experiment using three localized, high-current density sources mounted near the outboard midplane. The injected open field current relaxes via helicity-conserving magnetic turbulence into a tokamaklike magnetic topology where the maximum sustained plasma current is determined by helicity balance and the requirements for magnetic relaxation.
The Advanced Photon Source injection timing system

International Nuclear Information System (INIS)

Lenkszus, F.R.; Laird, R.

1995-01-01

The Advanced Photon Source consists of five accelerators. The injection timing system provides the signals required to cause a bunch emitted from the electron gun to navigate through intermediate accelerators to a specific bucket (1 out of 1296) within the storage ring. Two linacs and a positron accumulator ring operate at 60Hz while a booster synchrotron ramps and injects into the storage ring at 2Hz. The distributed, modular VME/VXI-based injection timing system is controlled by two EPICS-based input/output controllers (IOCs). Over 40 VME/VXI cards have been developed to implement the system. Card types range from 352MHz VXI timing modules to VME-based fiber optic fanouts and logic translators/drivers. All timing is distributed with fiber optics. Timing references are derived directly from machine low-level rf of 9.77MHz and 352MHz. The timing references provide triggers to programmable delay generators. Three grades of timing are provided. Precision timing is derived from commercial digital delay generators, intermediate precision timing is obtained from VXI 8-channel digital delay generators which provide timing with 25ns peak-to-peak jitter, and modest precision timing is provided by the APS event system. The timing system is fully integrated into the APS EPICS-based control system
High-current negative hydrogen ion beam production in a cesium-injected multicusp source

International Nuclear Information System (INIS)

Takeiri, Y.; Tsumori, K.; Kaneko, O.

1997-01-01

A high-current negative hydrogen ion source has been developed, where 16.2 A of the H - current was obtained with a current density of 31 mA/cm 2 . The ion source is a multicusp source with a magnetic filter for negative ion production, and cesium vapor is injected into the arc chamber, leading to enhancement of the negative ion yields. The cesium-injection effects are discussed, based on the experimental observations. Although the surface production of the negative ions on the cesium-covered plasma grid is thought to be a dominant mechanism of the H - current enhancement, the cesium effects in the plasma volume, such as the cesium ionization and the electron cooling, are observed, and could contribute to the improved operation of the negative ion source. (author)
Cosmic ray injection spectrum at the galactic sources

Science.gov (United States)

Lagutin, Anatoly; Tyumentsev, Alexander; Volkov, Nikolay

The spectra of cosmic rays measured at Earth are different from their source spectra. A key to understanding this difference, being crucial for solving the problem of cosmic-ray origin, is the determination of how cosmic-ray (CR) particles propagate through the turbulent interstellar medium (ISM). If the medium is a quasi-homogeneous the propagation process can be described by a normal diffusion model. However, during a last few decades many evidences, both from theory and observations, of the existence of multiscale structures in the Galaxy have been found. Filaments, shells, clouds are entities widely spread in the ISM. In such a highly non-homogeneous (fractal-like) ISM the normal diffusion model certainly is not kept valid. Generalization of this model leads to what is known as "anomalous diffusion". The main goal of the report is to retrieve the cosmic ray injection spectrum at the galactic sources in the framework of the anomalous diffusion (AD) model. The anomaly in this model results from large free paths ("Levy flights") of particles between galactic inhomogeneities. In order to evaluate the CR spectrum at the sources, we carried out new calculation of the CR spectra at Earth. AD equation in terms of fractional derivatives have been used to describe CR propagation from the nearby (r≤1 kpc) young (t≤ 1 Myr) and multiple old distant (r > 1 kpc) sources. The assessment of the key model parameters have been based on the results of the particles diffusion in the cosmic and laboratory plasma. We show that in the framework of the anomalous diffusion model the locally observed basic features of the cosmic rays (difference between spectral exponents of proton, He and other nuclei, "knee" problem, positron to electron ratio) can be explained if the injection spectrum at the main galactic sources of cosmic rays has spectral exponent p˜ 2.85. The authors acknowledge support from The Russian Foundation for Basic Research grant No. 14-02-31524.
Field demonstration of foam injection to confine a chlorinated solvent source zone.

Science.gov (United States)

Portois, Clément; Essouayed, Elyess; Annable, Michael D; Guiserix, Nathalie; Joubert, Antoine; Atteia, Olivier

2018-05-01

A novel approach using foam to manage hazardous waste was successfully demonstrated under active site conditions. The purpose of the foam was to divert groundwater flow, that would normally enter the source zone area, to reduce dissolved contaminant release to the aquifer. During the demonstration, foam was pre generated and directly injected surrounding the chlorinated solvent source zone. Despite the constraints related to the industrial activities and non-optimal position of the injection points, the applicability and effectiveness of the approach have been highlighted using multiple metrics. A combination of measurements and modelling allowed definition of the foam extent surrounding each injection point, and this appears to be the critical metric to define the success of the foam injection approach. Information on the transport of chlorinated solvents in groundwater showed a decrease of contaminant flux by a factor of 4.4 downstream of the confined area. The effective permeability reduction was maintained over a period of three months. The successful containment provides evidence for consideration of the use of foam to improve traditional flushing techniques, by increasing the targeting of contaminants by remedial agents. Copyright © 2018 Elsevier B.V. All rights reserved.
A Review of Galvanically Isolated Impedance-Source DC–DC Converters

DEFF Research Database (Denmark)

Chub, Andrii; Vinnikov, Dmitri; Blaabjerg, Frede

2016-01-01

Impedance-source converters, an emerging technology in electric energy conversion, overcome limitations of conventional solutions by the use of specific impedance-source networks. Focus of this paper is on the topologies of galvanically isolated impedance-source dc-dc converters. These converters...... isolated dc-dc converters according to the element that transfers energy from the input to the output: a transformer, a coupled inductor, or their combination. This classification reveals advantages and disadvantages, as well as a wide space for further research. This paper also outlines the most promising...

The Injection System of SAGA Light Source

CERN Document Server

Iwasaki, Yoshitaka; Ohgaki, Hideaki; Okajima, Toshihiro; Takabayashi, Yuichi; Tomimasu, Takio; Yoshida, Katuhide

2005-01-01

Saga light Source is a 1.4-GeV electron storage ring with a circumference of 75.6m. The injector is a 250-MeV linac producing 1 ms macro-pulse with a peak current of 12mA and repetition rate of 1Hz. The output beam from the linac is transported though a transport line, and injected into the ring though a septum magnet with a bending angle of 20-degree. The transport line consists of two bending magnets, two quadrupole doublelets, and a quadrupole singlet. The bump orbit is formed by four kicker magnets, two of which are installed at both sides of septum magnet, and other two are positioned apart by one magnet cell of the ring. They are excited by sinusoidal electric currents with a half width of 0.5 ms. The beam optics for the injection trajectory is computed and shown at control room, the parameters for which are provided directly from the power supply control server PC. The operator is able to see real-time result of the beam trajectory calculation. This tool is quite effective to optimize the magnets param...
Genetic characterization of Arcobacter isolates from various sources.

Science.gov (United States)

Shah, A H; Saleha, A A; Zunita, Z; Cheah, Y K; Murugaiyah, M; Korejo, N A

2012-12-07

Arcobacter is getting more attention due to its detection from wide host-range and foods of animal origin. The objective of this study was to determine the prevalence of Arcobacter spp. in various sources at farm level and beef retailed in markets in Malaysia and to assess the genetic relatedness among them. A total of 273 samples from dairy cattle including cattle (n=120), floor (n=30), water (n=18) and milk (n=105) as well as 148 beef samples collected from retail markets were studied. The overall prevalence of Arcobacter in various sources was 15% (63/421). However, source-wise detection rate of Arcobacter spp. was recorded as 26.66% (8/30) in floor, 26.3% (39/148) in beef, 11.11% (2/18) in water, 7.6% (8/105) in milk and 6.66% (8/120) in cattle. Arcobacter butzleri was the frequently isolated species however, a total of 75%, 66.7%, 53.8%, 50% and 12.5%% samples from floor, milk, beef, water and cattle, respectively, were carrying more than one species simultaneously. One (12.5%) cattle and beef sample (2.5%) found to be carrying one Arcobacter spp., A. skirrowii, only. Typing of Arcobacter isolates was done though pulsed field gel electrophoresis (PFGE) after digested with Eag1 restriction endonuclease (RE). Digestion of genomic DNA of Arcobacter from various sources yielded 12 major clusters (≥ 50% similarity) which included 29 different band patterns. A number of closely related A. butzleri isolates were found from beef samples which indicate cross contamination of common type of Arcobacter. Fecal shedding of Arcobacter by healthy animals can contaminate water and milk which may act as source of infection in humans. Copyright © 2012 Elsevier B.V. All rights reserved.
Jet flow analysis of liquid poison injection in a CANDU reactor using source term

International Nuclear Information System (INIS)

Chae, Kyung Myung; Choi, Hang Bok; Rhee, Bo Wook

2001-01-01

For the performance analysis of Canadian deuterium uranium (CANDU) reactor shutdown system number 2 (SDS2), a computational fluid dynamics model of poison jet flow has been developed to estimate the flow field and poison concentration formed inside the CANDU reactor calandria. As the ratio of calandria shell radius over injection nozzle hole diameter is so large (1055), it is impractical to develop a full-size model encompassing the whole calandria shell. In order to reduce the model to a manageable size, a quarter of one-pitch length segment of the shell was modeled using symmetric nature of the jet; and the injected jet was treated as a source term to avoid the modeling difficulty caused by the big difference of the hole sizes. For the analysis of an actual CANDU-6 SDS2 poison injection, the grid structure was determined based on the results of two-dimensional real- and source-jet simulations. The maximum injection velocity of the liquid poison is 27.8 m/s and the mass fraction of the poison is 8000 ppm (mg/kg). The simulation results have shown well-established jet flow field. In general, the jet develops narrowly at first but stretches rapidly. Then, the flow recirculates a little in r-x plane, while it recirculates largely in r-θ plane. As the time goes on, the adjacent jets contact each other and form a wavy front such that the whole jet develops in a plate form. his study has shown that the source term model can be effectively used for the analysis of the poison injection and the simulation result of the CANDU reactor is consistent with the model currently being used for the safety analysis. In the future, it is strongly recommended to analyze the transient (from helium tank to injection nozzle hole) of the poison injection by applying Bernoulli equation with real boundary conditions
Genetic diversity of Enterococcus faecalis isolated from environmental, animal and clinical sources in Malaysia

Directory of Open Access Journals (Sweden)

Diane S. Daniel

2017-09-01

Full Text Available Enterococcus faecalis ranks as one of the leading causes of nosocomial infections. A strong epidemiological link has been reported between E. faecalis inhabiting animals and environmental sources. This study investigates the genetic diversity, antibiotic resistance and virulence determinants in E. faecalis from three sources in Malaysia. A total of 250 E. faecalis isolates were obtained consisting of 120 isolates from farm animals, 100 isolates from water sources and 30 isolates from hospitalized patients. Pulse-field gel electrophoresis-typing yielded 63 pulsotypes, with high diversity observed in all sources (D = ≥0.901. No pulsotype was common to all the three sources. Each patient room had its own unique PFGE pattern which persisted after six months. Minimum inhibitory concentrations of Vancomycin, Gentamicin, Penicillin, Tetracycline, Nitrofurantoin, Levofloxacin, Ciprofloxacin and Fosfomycin were evaluated. Resistance to Tetracycline was most prevalent in isolates from farm animals (62% and water sources (49%. Water isolates (86% had a higher prevalence of the asa1 gene, which encodes for aggregation substance, whereas clinical (78% and farm animal isolates (87% had a higher prevalence of the esp gene, encoding a surface exposed protein. This study generates knowledge on the genetic diversity of E. faecalis with antibiotic resistance and virulence characteristics from various sources in Malaysia. Keywords: Antibiotic resistance, Enterococcus faecalis, Genetic diversity, Molecular typing, Virulence markers
An ion source upgrade for an axial injection based commercial cyclotron

International Nuclear Information System (INIS)

Dehnel, M.P.; Stewart, T.; Roeder, M.; Le Du, K.

2005-01-01

The TRIUMF H - volume-cusp ion source technology licensed by Dehnel Consulting Ltd ranges in output current from 1 to 15 mA with beam energies in the 22-30 keV range. For those Cyclone 30 cyclotrons installed with an early 1980's style Lawrence Berkeley Lab (LBL) volume-cusp ion source, an upgrade to a 5 mA TRIUMF H - volume-cusp ion source would pay dividends in terms of longer filament, filament post and ion source lens lifetime, as well as less eroded material build-up in the source. In addition, the 5 mA ion source would approximately double the beam current available to inject into the cyclotron while reducing the emittance by about a factor of four. The new system has the potential to significantly boost radioisotope production at Cyclone 30 facilities utilizing the older style LBL ion source
Review of MEVVA ion source performance for accelerator injection

International Nuclear Information System (INIS)

Brown, I.G.; Godechot, X.; Spaedtke, P.; Emig, H.; Rueck, D.M.; Wolf, B.H.

1991-05-01

The Mevva (metal vapor vacuum arc) ion source provides high current beams of multiply-charged metal ions suitable for use in heavy ion synchrotrons as well as for metallurgical ion implantation. Pulsed beam currents of up to several amperes can be produced at ion energies of up to several hundred keV. Operation has been demonstrate for 48 metallic ion species: Li, C, Mg, Al, Si, Ca, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Ge, Sr, Y, Zr, Nb, Mo, Pd, Ag, Cd, In, Sn, Ba, La, Ce, Pr, Nd, Sm, Gd, Dy, Ho, Er, Yb, Hf, Ta, W, Ir, Pt, Au, Pb, Bi, Th and U. When the source is operated optimally the rms fractional beam noise can be as low as 7% of the mean beam current; and when properly triggered the source operates reliably and reproducibly for many tens of thousands of pulses without failure. In this paper we review the source performance referred specifically to its use for synchrotron injection. 15 refs., 3 figs
Plasma jet source parameter optimisation and experiments on injection into Globus-M spherical tokamak

International Nuclear Information System (INIS)

Gusev, V.K.; Petrov, Yu.V.; Sakharov, N.V.; Semenov, A.A.; Voronin, A.V.

2005-01-01

Results of theoretical and experimental research on the plasma sources and injection of plasma and gas jet produced by the modified source into tokamak Globus-M are presented. An experimental test stand was developed for investigation of intense plasma jet generation. Optimisation of pulsed coaxial accelerator parameters by means of analytical calculations is performed with the aim of achieving the highest flow velocity at limited coaxial electrode length and discharge current. The optimal parameters of power supply to generate a plasma jet with minimal impurity contamination and maximum flow velocity were determined. A comparison of experimental and calculation results is made. Plasma jet parameters are measured, such as: impurity species content, pressure distribution across the jet, flow velocity, plasma density, etc. Experiments on the interaction of a higher kinetic energy plasma jet with the magnetic field and plasma of the Globus-M tokamak were performed. Experimental results on plasma and gas jet injection into different Globus-M discharge phases are presented and discussed. Results are presented on the investigation of plasma jet injection as the source for discharge breakdown, plasma current startup and initial density rise. (author)
Laser Ion Source Development for ISOL Systems at RIA

CERN Document Server

Liu, Yuan; Beene, James R; Bilheux, Hassina Z; Brueck, Kim; Geppert, Christopher; Havener, Charles; Kessler, Thomas; Krause, Herbert F; Schultz, David R; Stracener, Dan; Vane, C R; Wendt, Klaus

2005-01-01

The isobaric purity of radioactive ion beams (RIBs) is of crucial importance to many experiments. Laser ion sources based on resonant photoionization have already proved to be of great value at existing ISOL RIB facilities. In these ion sources, ions of a selected isotope are produced by laser radiation via stepwise atomic resonant excitations followed by ionization in the last transition. Because each element has its own unique atomic energy levels, the resonant photoionization process can provide elemental selectivity of nearly 100%. We have initiated a research effort to develop a prototype laser ion source with the potential to achieve the high selectivity and high efficiency required for research with ISOL-generated RIBs at the Rare Isotope Accelerator (RIA). A pilot experiment has been conducted to demonstrate resonant photoionization of three atomic species using all-solid-state tunable Ti:Sapphire lasers. Three Ti:Sapphire lasers were provided by the University of Mainz and used in the experiment for ...
A high voltage gain quasi Z-source isolated DC/DC converter

DEFF Research Database (Denmark)

Siwakoti, Yam P.; Blaabjerg, Frede; Loh, Poh Chiang

2014-01-01

A compact quasi-Z-source DC/DC converter is presented with high voltage gain, isolated output, and improved efficiency. The improvements in size and performance were achieved by using a square wave inverter with only two output switches driving an isolating transformer in push-pull mode, followed...... by a voltage doubling output rectifier. The converter is well-suited to applications requiring a high voltage gain, especially renewable energy sources such as photovoltaic and fuel-cell power supplies. To demonstrate the converter's performance a prototype designed to output 400 V at 500 W was constructed...
Modification to the accelerator of the NBI-1B ion source for improving the injection efficiency

International Nuclear Information System (INIS)

Kim, T. S.; Jeong, S. H.; Chang, D. H.; In, S. R.; Park, M.; Jung, B. K.; Lee, K. W.; Wang, S. J.; Bae, Y. S.; Park, H. T.; Kim, J. S.; Cho, W.; Choi, D. J.

2016-01-01

Minimizing power loss of a neutral beam imposes modification of the accelerator of the ion source for further improvement of the beam optics. The beam optics can be improved by focusing beamlets. The injection efficiencies by the steering of ion beamlets are investigated numerically to find the optimum modification of the accelerator design of the NBI-1B ion source. The beam power loss was reduced by aperture displacement of three edge beamlets arrays considering power loadings on the beamline components. Successful testing and operation of the ion source at 60 keV/84% of injection efficiency led to the possibility of enhancing the system capability to a 2.4 MW power level at 100 keV/1.9 μP
Impact of three-dimensional geometry on the performance of isolated electron-injection infrared detectors

Energy Technology Data Exchange (ETDEWEB)

Fathipour, Vala; Jang, Sung Jun; Nia, Iman Hassani; Mohseni, Hooman, E-mail: hmohseni@northwestern.edu [Bio-Inspired Sensors and Optoelectronics Laboratory, Northwestern University, 2145 Sheridan Rd, Evanston, Illinois 60208 (United States)

2015-01-12

We present a quantitative study of the influence of three-dimensional geometry of the isolated electron–injection detectors on their characteristics. Significant improvements in the device performance are obtained as a result of scaling the injector diameter with respect to the trapping/absorbing layer diameters. Devices with about ten times smaller injector area with respect to the trapping/absorbing layer areas show more than an order of magnitude lower dark current, as well as an order of magnitude higher optical gain compared with devices of same size injector and trapping/absorbing layer areas. Devices with 10 μm injector diameter and 30 μm trapping/absorbing layer diameter show an optical gain of ∼2000 at bias voltage of −3 V with a cutoff wavelength of 1700 nm. Analytical expressions are derived for the electron-injection detector optical gain to qualitatively explain the significance of scaling the injector with respect to the absorber.
ELECTRON CLOUD AT COLLIMATOR AND INJECTION REGION OF THE SPALLATION NEUTRON SOURCE ACCUMULATOR RING

International Nuclear Information System (INIS)

WANG, L.; HSEUH, H.-C.; LEE, Y.Y.; RAPARIA, D.; WEI, J.; COUSINEAU, S.

2005-01-01

The beam loss along the Spallation Neutron Source's accumulator ring is mainly located at the collimator region and injection region. This paper studied the electron cloud build-up at these two regions with the three-dimension program CLOUDLAND
Glyphosate Utilization as the Source of Carbon: Isolation and Identification of new Bacteria

Directory of Open Access Journals (Sweden)

M. Mohsen Nourouzi

2011-01-01

Full Text Available Mixed bacteria from oil palm plantation soil (OPS were isolated to investigate their ability to utilize glyphosate as carbon source. Results showed that approximately all of the glyphosate was converted to aminomethyl-phosphonic acid (AMPA (99.5%. It is worthy to note that mixed bacteria were able to degrade only 2% of AMPA to further metabolites. Two bacterial strains i.e. Stenotrophomonas maltophilia and Providencia alcalifaciens were obtained from enrichment culture. Bacterial isolates were cultured individually on glyphosate as a sole carbon source. It was observed that both isolates were able to convert glyphosate to AMPA.
Exploration of renewable sources for isolated systems

OpenAIRE

Apolo, Cristhian Agustin Apolo

2017-01-01

Providing universal access to electricity is a priority worldwide. Renewable Energy Sources (RES) play an important role in the supply of energy to rural and remote areas, where grid electricity is not available, or the cost of the grid extension is excessively. Isolated communities in the Amazon region of Ecuador are frequently far away from each other, formed by scattered housing, exhibit very low population density, and are surrounded by dense vegetation. Supplying such communities is typi...
Injection system of compact SR light source 'AURORA'

International Nuclear Information System (INIS)

Takayama, Takeshi; Yano, Takashi; Sasaki, Yasushi; Yasumitsu, Naoki

1991-01-01

A half-integer-resonance injection method is introduced for a superconducting SR-ring of 1 m orbit diameter, which is made of a weak focussing single-body magnet. The present method makes it possible to inject an electron beam of an energy of as high as 150 MeV into the ring of a magnetic field strength of 1 T. Several new injection devices are introduced in order to guide the beam under the strong magnetic fringing field, and to excite the half-integer-resonance. The field index of 0.73 is selected for the half-integer-resonance injection. The field index of 0.35 at the maximum magnetic field strength of 4.3 T is to get a sufficiently long quantum lifetime. A new device named resonance jumper is used to pass quickly several resonances of betatron motion without beam loss. The resonances occur when the magnetic field is ramped up and the field index decreases from 0.73 to 0.35. The injection devices except the inflector are air-core magnets in order to work in the strong magnetic field. In November of 1989, the beam was successfully injected and stored. The injection devices and the half-integer-resonance injection method were established. (author)
Physics of the current injection process during localized helicity injection

Science.gov (United States)

Hinson, Edward Thomas

An impedance model has been developed for the arc-plasma cathode electron current source used in localized helicity injection tokamak startup. According to this model, a potential double layer (DL) is established between the high-density arc plasma (narc ˜ 1021 m-3) in the electron source, and the less-dense external tokamak edge plasma (nedge ˜ 10 18 m-3) into which current is injected. The DL launches an electron beam at the applied voltage with cross-sectional area close to that of the source aperture: Ainj ≈ 2 cm 2. The injected current, Iinj, increases with applied voltage, Vinj, according to the standard DL scaling, Iinj ˜ V(3/2/ inj), until the more restrictive of two limits to beam density nb arises, producing Iinj ˜ V(1/2/inj), a scaling with beam drift velocity. For low external tokamak edge density nedge, space-charge neutralization of the intense electron beam restricts the injected beam density to nb ˜ nedge. At high Jinj and sufficient edge density, the injected current is limited by expansion of the DL sheath, which leads to nb ˜ narc. Measurements of narc, Iinj , nedge, Vinj, support these predicted scalings, and suggest narc as a viable control actuator for the source impedance. Magnetic probe signals ≈ 300 degrees toroidally from the injection location are consistent with expectations for a gyrating, coherent electron beam with a compact areal cross-section. Technological development of the source has allowed an extension of the favorable Iinj ˜ V(1/2/inj) to higher power without electrical breakdown.
Antibiotic resistance profiling and phenotyping of Aeromonas species isolated from aquatic sources

Directory of Open Access Journals (Sweden)

Olumide A. Odeyemi

2017-01-01

Full Text Available This study aimed to investigate antibiotics resistance pattern and phenotyping of Aeromonas species isolated from different aquatic sources in Melaka, Malaysia. A total of 53 Aeromonas species were isolated from the following sources: sediment (n = 13, bivalve (n = 10, sea cucumber (n = 16 and sea water (n = 14 and resistance to 12 antibiotics – Tetracycline (30 μg, Kanamycin (30 μg, Oxytetracycline (30 μg, Ampicillin (10 μg, Streptomycin (10 μg, Gentamicin (10 μg, Sulphamethoxazole (25 μg, Nalixidic acid (30 μg, Trimethoprim (1.25 μg, Novobiocin (5 μg, Penicilin (10 μg and Chloramphenicol (10 μg was tested. The results obtained from this study reveal multi drug resistance pattern among the isolates. All the isolates were completely resistant to Ampicillin, Novobiocin, Sulphamethoxazole and Trimethoprim, respectively but susceptible to Tetracycline (100%, Kanamycin (5.7%, Gentamicin (5.7% and Oxytetracycline (24.5%. Antibiotics phenotyping of the bacteria revealed 21 different phenotypes among the isolates.
Gas Injection And Fast Pressure-Rise Measurements For The Linac4 H− Source

CERN Document Server

Mahner, E; Lettry, J; Mattei, S; O'Neil, M; Neupert, H; Pasquino, C; Schmitzer, C

2013-01-01

In the era of the Large Hadron Collider, the CERN injector complex comprising the 34 years old Linac2 with its primary proton source, is presently upgraded with a new linear accelerator for H− (Linac4). The design, construction, and test of volume production and cesiated RF-driven H− ion sources is presently ongoing with the final goal of producing an H− beam with 80 mA beam current, 45 keV beam energy, 500 s pulse length, and a repetition rate of 2 Hz. In order to have quantitative information of the hydrogen gas density at the moment of plasma ignition the dynamic vacuum properties of the plasma generator were studied experimentally. We describe the experimental setup and present fast pressure-rise measurements for different parameters of the gas injection system, such as gas species (H2, He, N2, Ar), piezo valve voltage pulse length (200 - 500 s), and injection pressure (400 - 2800 mbar). The obtained data are compared with a conductance model of the plasma generator.
Proton injection and RF capture in the national spallation neutron source

International Nuclear Information System (INIS)

Luccio, A.U.; Beebe-Wang, J.; Maletic, D.

1997-01-01

The accelerator system for the 1 to 5 MW National Spallation Neutron Source (NSNS) consists of a linac followed by a 1 GeV proton accumulator ring. Since the ring is a very high current machine, the injection and rf capture of the protons is deeply affected by transverse and longitudinal space charge effects. Results of numerical simulation of the process are presented together with considerations on methods and results of space charge treatment in high intensity proton storage rings
Development and Characterization of a Metal Injection Molding Bio Sourced Inconel 718 Feedstock Based on Polyhydroxyalkanoates

Directory of Open Access Journals (Sweden)

Alexandre Royer

2016-04-01

Full Text Available The binder plays the most important role in the metal injection molding (MIM process. It provides fluidity of the feedstock mixture and adhesion of the powder to keep the molded shape during injection molding. The binder must provide strength and cohesion for the molded part and must be easy to remove from the molded part. Moreover, it must be recyclable, environmentally friendly and economical. Also, the miscibility between polymers affects the homogeneity of the injected parts. The goal of this study is to develop a feedstock of superalloy Inconel 718 that is environmentally friendly. For these different binders, formulations based on polyethylene glycol (PEG, because of his water solubility property, and bio sourced polymers were studied. Polyhydroxyalkanoates (PHA were investigated as a bio sourced polymer due to its miscibility with the PEG. The result is compared to a standard formulation using polypropylene (PP. The chemical and rheological behavior of the binder formulation during mixing, injection and debinding process were investigated. The feedstock was characterized in the same way as the binders and the interactions between the powder and the binders were also studied. The results show the well adapted formulation of polymer binder to produce a superalloy Inconel 718 feedstock.

Measurements on Pb27+ Sources for the CERN Heavy Ion Injection Chain

CERN Document Server

Chamings, J A

2004-01-01

CERN, the world's largest particle physics laboratory near Geneva, is currently in the process of building the Large Hadron Collider (LHC). Lead-208 will be used in this accelerator and to meet the injection requirements much work is required to find a suitable and reliable heavy ion source. The work in this report covers two ion sources, the Laser Ion Source (LIS), and the Electron Cyclotron Resonance Ion Source (ECRIS). An emittance measurement, using a pepper pot and CCD camera, was completed on the recently re-installed LIS, measured and analysed to be 140mm.mrad un-normalised and 0.8mm.mrad normalised 4rms for the maximum intensity charge state, Pb27+. A Visual Basic Program was modified to allow Charge State Distribution (CSD) and other scans of the ECRIS at CERN to be taken. Chapter 5 presents the results of the CSD scans taken. This program provided a new method to take 1 dimensional transverse beam profiles. From this a direct emittance measurement was formed for the first time since the source was o...
Recent developments of target and ion sources to produce ISOL beams

CERN Document Server

Stora, Thierry

2013-01-01

In this review on target and ion sources for ISOL (Isotope Separation OnLine) beams, important develop- ments from the past five years are highlighted. While at precedent EMIS conferences, a particular focus was given to a single topics, for instance specifically on ion sources or on chemical purification tech- niques, here each of the important elements present in an ISOL production unit is discussed. Fast diffus- ing nanomaterials, uranium-based targets, high power targets for next generation facilities, purification by selective adsorption, new ion sources are all part of this review. For each of these selected topics, the reported results lead to significant gains in intensity, purity, or quality of the delivered beam, or in the production of new isotope beams. Often the outcome resulted from the combination of original ideas with state-of-the-art investigations; this was carried out using very different scientific disciplines, lead- ing to understanding of the underlying chemical or physical mechanisms a...
Double input converters for different voltage sources with isolated charger

Directory of Open Access Journals (Sweden)

Chalash Sattayarak

2014-09-01

Full Text Available This paper presents the double input converters for different voltage input sources with isolated charger coils. This research aims to increase the performance of the battery charger circuit. In the circuit, there are the different voltage levels of input source. The operating modes of the switch in the circuit use the microcontroller to control the battery charge and to control discharge mode automatically when the input voltage sources are lost from the system. The experimental result of this research shows better performance for charging at any time period of the switch, while the voltage input sources work together. Therefore, this research can use and develop to battery charger for present or future.
Efficacy of intra-articular hyaluronic acid injections and exercise-based rehabilitation programme, administered as isolated or integrated therapeutic regimens for the treatment of knee osteoarthritis.

Science.gov (United States)

Saccomanno, Maristella F; Donati, Fabrizio; Careri, Silvia; Bartoli, Matteo; Severini, Gabriele; Milano, Giuseppe

2016-05-01

To assess the efficacy of intra-articular hyaluronic acid (HA) injections and exercise-based rehabilitation (EBR) programme, administered as isolated or integrated for the treatment of knee osteoarthritis. One hundred sixty-five patients affected by moderate degrees of knee OA were randomly divided into three groups. Group 1 (HA) underwent three HA injections (one every 2 weeks); group 2 (EBR) underwent 20 treatment sessions in a month of an individualized programme; and group 3 (HA + EBR) received both treatments simultaneously. Primary outcome was the Italian version of the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index; secondary outcome was the evaluation of active range of movement (AROM). All patients were evaluated before and 1, 3 and 6 months after treatment. Significance was set at p injections and individualized rehabilitation programmes administered in isolation or in combination are effective in improving knee function and pain relief. The combined treatment showed the greatest pain relief at 1-month follow-up compared to either in isolation. Compared to the previous studies, this is the first study, which proposed an EBR programme tailored to the compartment of the knee joint most involved in the degenerative process. I.
New high temperature plasma ion source for the TRISTAN ISOL facility

International Nuclear Information System (INIS)

Piotrowski, A.; Gill, R.L.; McDonald, D.C.

1986-08-01

A vigorous program of ion source development at TRISTAN has led to several types of ion sources that are especially suited to extended operation at a reactor-based ISOL facility. The latest of these is a high temperature plasma ion source in which a 5 gm 235 U target is located in the cathode and can be heated to 2500 0 C. The ion source has a lifetime of >1000 hours and produces a wide array of elements, including Pd. Off-line investigations indicate that the source functions primarily in an electron impact mode of ionization and exhibits typical ionzation efficiencies of >30% for Xe
A bremsstrahlung gamma-ray source based on stable ionization injection of electrons into a laser wakefield accelerator

Energy Technology Data Exchange (ETDEWEB)

Döpp, A., E-mail: andreas.doepp@polytechnique.edu [LOA, ENSTA ParisTech, CNRS, École polytechnique, Université Paris-Saclay, 828 bd des Maréchaux, 91762 Palaiseau Cedex (France); Centro de Laseres Pulsados, Parque Cientfico, 37185 Villamayor, Salamanca (Spain); Guillaume, E.; Thaury, C.; Lifschitz, A. [LOA, ENSTA ParisTech, CNRS, École polytechnique, Université Paris-Saclay, 828 bd des Maréchaux, 91762 Palaiseau Cedex (France); Sylla, F. [SourceLAB SAS, 86 rue de Paris, 91400 Orsay (France); Goddet, J-P.; Tafzi, A.; Iaquanello, G.; Lefrou, T.; Rousseau, P. [LOA, ENSTA ParisTech, CNRS, École polytechnique, Université Paris-Saclay, 828 bd des Maréchaux, 91762 Palaiseau Cedex (France); Conejero, E.; Ruiz, C. [Departamento de Física Aplicada, Universidad de Salamanca, Plaza de laMerced s/n, 37008 Salamanca (Spain); Ta Phuoc, K.; Malka, V. [LOA, ENSTA ParisTech, CNRS, École polytechnique, Université Paris-Saclay, 828 bd des Maréchaux, 91762 Palaiseau Cedex (France)

2016-09-11

Laser wakefield acceleration permits the generation of ultra-short, high-brightness relativistic electron beams on a millimeter scale. While those features are of interest for many applications, the source remains constraint by the poor stability of the electron injection process. Here we present results on injection and acceleration of electrons in pure nitrogen and argon. We observe stable, continuous ionization-induced injection of electrons into the wakefield for laser powers exceeding a threshold of 7 TW. The beam charge scales approximately with the laser energy and is limited by beam loading. For 40 TW laser pulses we measure a maximum charge of almost 1 nC per shot, originating mostly from electrons of less than 10 MeV energy. The relatively low energy, the high charge and its stability make this source well-suited for applications such as non-destructive testing. Hence, we demonstrate the production of energetic radiation via bremsstrahlung conversion at 1 Hz repetition rate. In accordance with GEANT4 Monte-Carlo simulations, we measure a γ-ray source size of less than 100 μm for a 0.5 mm tantalum converter placed at 2 mm from the accelerator exit. Furthermore we present radiographs of image quality indicators.
Magnetically coupled high-gain Y-source isolated DC/DC converter

DEFF Research Database (Denmark)

Siwakoti, Yam P.; Loh, Poh Chiang; Blaabjerg, Frede

2014-01-01

A new form of magnetically coupled DC/DC converter is proposed for medium power applications (250 W to 2 kW), requiring a high-voltage gain, short inductive charging time and galvanic isolation. The proposed converter can be realised using a unique Y-source impedance network and a two-switch push...
The direct injection of intense ion beams from a high field electron cyclotron resonance ion source into a radio frequency quadrupole.

Science.gov (United States)

Rodrigues, G; Becker, R; Hamm, R W; Baskaran, R; Kanjilal, D; Roy, A

2014-02-01

The ion current achievable from high intensity ECR sources for highly charged ions is limited by the high space charge. This makes classical extraction systems for the transport and subsequent matching to a radio frequency quadrupole (RFQ) accelerator less efficient. The direct plasma injection (DPI) method developed originally for the laser ion source avoids these problems and uses the combined focusing of the gap between the ion source and the RFQ vanes (or rods) and the focusing of the rf fields from the RFQ penetrating into this gap. For high performance ECR sources that use superconducting solenoids, the stray magnetic field of the source in addition to the DPI scheme provides focusing against the space charge blow-up of the beam. A combined extraction/matching system has been designed for a high performance ECR ion source injecting into an RFQ, allowing a total beam current of 10 mA from the ion source for the production of highly charged (238)U(40+) (1.33 mA) to be injected at an ion source voltage of 60 kV. In this design, the features of IGUN have been used to take into account the rf-focusing of an RFQ channel (without modulation), the electrostatic field between ion source extraction and the RFQ vanes, the magnetic stray field of the ECR superconducting solenoid, and the defocusing space charge of an ion beam. The stray magnetic field is shown to be critical in the case of a matched beam.
The direct injection of intense ion beams from a high field electron cyclotron resonance ion source into a radio frequency quadrupole

Science.gov (United States)

Rodrigues, G.; Becker, R.; Hamm, R. W.; Baskaran, R.; Kanjilal, D.; Roy, A.

2014-02-01

The ion current achievable from high intensity ECR sources for highly charged ions is limited by the high space charge. This makes classical extraction systems for the transport and subsequent matching to a radio frequency quadrupole (RFQ) accelerator less efficient. The direct plasma injection (DPI) method developed originally for the laser ion source avoids these problems and uses the combined focusing of the gap between the ion source and the RFQ vanes (or rods) and the focusing of the rf fields from the RFQ penetrating into this gap. For high performance ECR sources that use superconducting solenoids, the stray magnetic field of the source in addition to the DPI scheme provides focusing against the space charge blow-up of the beam. A combined extraction/matching system has been designed for a high performance ECR ion source injecting into an RFQ, allowing a total beam current of 10 mA from the ion source for the production of highly charged 238U40+ (1.33 mA) to be injected at an ion source voltage of 60 kV. In this design, the features of IGUN have been used to take into account the rf-focusing of an RFQ channel (without modulation), the electrostatic field between ion source extraction and the RFQ vanes, the magnetic stray field of the ECR superconducting solenoid, and the defocusing space charge of an ion beam. The stray magnetic field is shown to be critical in the case of a matched beam.
Reduction of plasma density in the Helicity Injected Torus with Steady Inductance experiment by using a helicon pre-ionization source

International Nuclear Information System (INIS)

Hossack, Aaron C.; Jarboe, Thomas R.; Victor, Brian S.; Firman, Taylor; Prager, James R.; Ziemba, Timothy; Wrobel, Jonathan S.

2013-01-01

A helicon based pre-ionization source has been developed and installed on the Helicity Injected Torus with Steady Inductance (HIT-SI) spheromak. The source initiates plasma breakdown by injecting impurity-free, unmagnetized plasma into the HIT-SI confinement volume. Typical helium spheromaks have electron density reduced from (2–3) × 10 19 m −3 to 1 × 10 19 m −3 . Deuterium spheromak formation is possible with density as low as 2 × 10 18 m −3 . The source also enables HIT-SI to be operated with only one helicity injector at injector frequencies above 14.5 kHz. A theory explaining the physical mechanism driving the reduction of breakdown density is presented
A new high-temperature plasma ion source for the TRISTAN ISOL facility

International Nuclear Information System (INIS)

Piotrowski, A.; Gill, R.L.; McDonald, D.C.

1987-01-01

A vigorous program of ion-source development at TRISTAN has led to several types of ion sources that are especially suited to extended operation at a reactor-based ISOL facility. The latest of these is a high-temperature plasma ion source in which a 5-g 235 U target is located in the cathode and can be heated to 2500 0 C. The ion source has a lifetime of >1000 h and produces a wide array of elements, including palladium. Off-line investigations indicate that the source functions primarily in an electron impact mode of ionization and exhibits typical ionization efficiencies of >30% for xenon. (orig.)
A new high-temperature plasma ion source for the TRISTAN ISOL facility

International Nuclear Information System (INIS)

Piotrowski, A.; Gill, R.L.; McDonald, D.C.

1987-01-01

A vigorous program of ion-source development at TRISTAN has led to several types of ion sources that are especially suited to extended operation at a reactor-based ISOL facility. The latest of these is a high-temperature plasma ion source in which a 5-g /sup 235/U target is located in the cathode and can be heated to 2500 0 C. The ion source has a lifetime of > 1000 h and produces a wide array of elements, including palladium. Off-line investigations indicate that the source functions primarily in an electron impact mode of ionization and exhibits typical ionization efficiencies of > 30% for xenon
ITER Neutral Beam Injection System

International Nuclear Information System (INIS)

Ohara, Yoshihiro; Tanaka, Shigeru; Akiba, Masato

1991-03-01

A Japanese design proposal of the ITER Neutral Beam Injection System (NBS) which is consistent with the ITER common design requirements is described. The injection system is required to deliver a neutral deuterium beam of 75MW at 1.3MeV to the reactor plasma and utilized not only for plasma heating but also for current drive and current profile control. The injection system is composed of 9 modules, each of which is designed so as to inject a 1.3MeV, 10MW neutral beam. The most important point in the design is that the injection system is based on the utilization of a cesium-seeded volume negative ion source which can produce an intense negative ion beam with high current density at a low source operating pressure. The design value of the source is based on the experimental values achieved at JAERI. The utilization of the cesium-seeded volume source is essential to the design of an efficient and compact neutral beam injection system which satisfies the ITER common design requirements. The critical components to realize this design are the 1.3MeV, 17A electrostatic accelerator and the high voltage DC acceleration power supply, whose performances must be demonstrated prior to the construction of ITER NBI system. (author)
Tectonic isolation from regional sediment sourcing of the Paradox Basin

Science.gov (United States)

Smith, T. M.; Saylor, J.; Sundell, K. E.; Lapen, T. J.

2017-12-01

The Appalachian and Ouachita-Marathon mountain ranges were created by a series of tectonic collisions that occurred through the middle and late Paleozoic along North America's eastern and southern margins, respectively. Previous work employing detrital zircon U-Pb geochronology has demonstrated that fluvial and eolian systems transported Appalachian-derived sediment across the continent to North America's Paleozoic western margin. However, contemporaneous intraplate deformation of the Ancestral Rocky Mountains (ARM) compartmentalized much of the North American western interior and mid-continent. We employ lithofacies characterization, stratigraphic thickness, paleocurrent data, sandstone petrography, and detrital zircon U-Pb geochronology to evaluate source-sink relationships of the Paradox Basin, which is one of the most prominent ARM basins. Evaluation of provenance is conducted through quantitative comparison of detrital zircon U-Pb distributions from basin samples and potential sources via detrital zircon mixture modeling, and is augmented with sandstone petrography. Mixing model results provide a measure of individual source contributions to basin stratigraphy, and are combined with outcrop and subsurface data (e.g., stratigraphic thickness and facies distributions) to create tectonic isolation maps. These maps elucidate drainage networks and the degree to which local versus regional sources influence sediment character within a single basin, or multiple depocenters. Results show that despite the cross-continental ubiquity of Appalachian-derived sediment, fluvial and deltaic systems throughout much of the Paradox Basin do not record their influence. Instead, sediment sourcing from the Uncompahgre Uplift, which has been interpreted to drive tectonic subsidence and formation of the Paradox Basin, completely dominated its sedimentary record. Further, the strong degree of tectonic isolation experienced by the Paradox Basin appears to be an emerging, yet common
The direct injection of intense ion beams from a high field electron cyclotron resonance ion source into a radio frequency quadrupole

Energy Technology Data Exchange (ETDEWEB)

Rodrigues, G., E-mail: gerosro@gmail.com; Kanjilal, D.; Roy, A. [Inter University Accelerator Centre, Aruna Asaf Ali Marg, New Delhi (India); Becker, R. [Institut fur Angewandte Physik der Universitaet, D-60054 Frankfurt/M (Germany); Hamm, R. W. [R and M Technical Enterprises, Inc., 4725 Arlene Place, Pleasanton, California 94566 (United States); Baskaran, R. [Indira Gandhi Centre for Atomic Research, Kalpakkam, Tamilnadu (India)

2014-02-15

The ion current achievable from high intensity ECR sources for highly charged ions is limited by the high space charge. This makes classical extraction systems for the transport and subsequent matching to a radio frequency quadrupole (RFQ) accelerator less efficient. The direct plasma injection (DPI) method developed originally for the laser ion source avoids these problems and uses the combined focusing of the gap between the ion source and the RFQ vanes (or rods) and the focusing of the rf fields from the RFQ penetrating into this gap. For high performance ECR sources that use superconducting solenoids, the stray magnetic field of the source in addition to the DPI scheme provides focusing against the space charge blow-up of the beam. A combined extraction/matching system has been designed for a high performance ECR ion source injecting into an RFQ, allowing a total beam current of 10 mA from the ion source for the production of highly charged {sup 238}U{sup 40+} (1.33 mA) to be injected at an ion source voltage of 60 kV. In this design, the features of IGUN have been used to take into account the rf-focusing of an RFQ channel (without modulation), the electrostatic field between ion source extraction and the RFQ vanes, the magnetic stray field of the ECR superconducting solenoid, and the defocusing space charge of an ion beam. The stray magnetic field is shown to be critical in the case of a matched beam.
Reduction of plasma density in the Helicity Injected Torus with Steady Inductance experiment by using a helicon pre-ionization source

Energy Technology Data Exchange (ETDEWEB)

Hossack, Aaron C.; Jarboe, Thomas R.; Victor, Brian S. [Department of Aeronautics and Astronautics, University of Washington, Seattle, Washington 98195 (United States); Firman, Taylor; Prager, James R.; Ziemba, Timothy [Eagle Harbor Technologies, Inc., 119 W. Denny Way, Suite 210, Seattle, Washington 98119 (United States); Wrobel, Jonathan S. [979B West Moorhead Circle, Boulder, Colorado 80305 (United States)

2013-10-15

A helicon based pre-ionization source has been developed and installed on the Helicity Injected Torus with Steady Inductance (HIT-SI) spheromak. The source initiates plasma breakdown by injecting impurity-free, unmagnetized plasma into the HIT-SI confinement volume. Typical helium spheromaks have electron density reduced from (2–3) × 10{sup 19} m{sup −3} to 1 × 10{sup 19} m{sup −3}. Deuterium spheromak formation is possible with density as low as 2 × 10{sup 18} m{sup −3}. The source also enables HIT-SI to be operated with only one helicity injector at injector frequencies above 14.5 kHz. A theory explaining the physical mechanism driving the reduction of breakdown density is presented.
Genetic diversity and antibiogram profile of diarrhoeagenic Escherichia coli pathotypes isolated from human, animal, foods and associated environmental sources

Directory of Open Access Journals (Sweden)

Pankaj Dhaka

2016-05-01

Full Text Available Introduction: Infectious diarrhoea particularly due to pathogenic bacteria is a major health problem in developing countries, including India. Despite significant reports of diarrhoeagenic Escherichia coli (DEC pathotypes around the globe, studies which address genetic relatedness, antibiogram profile and their correlation with respect to their isolation from different sources are sparse. The present study determines isolation and identification of DEC pathotypes from different sources, their genetic characterisation, antibiogram profile and their correlation if any. Materials and methods: A total of 336 samples comprising diarrhoeic stool samples from infants (n=103, young animal (n=106, foods (n=68 and associated environmental sources (n=59 were collected from Bareilly region of India. All the samples were screened by using standard microbiological methods for the detection of E. coli. The identified E. coli were then confirmed as DEC pathotypes using polymerase chain reaction–based assays. Those DEC pathotypes identified as Enteroaggregative E. coli (EAEC were further confirmed using HEp-2 adherence assay. All the isolated DEC pathotypes were studied for their genetic diversity using pulsed-field gel electrophoresis (PFGE, and antimicrobial susceptibility testing was performed by using disc diffusion method as per Clinical Laboratory Standards Institute guidelines. Results and discussion: Of the four DEC pathotypes investigated, EAEC was found to be the predominant pathogen with an isolation rate of 16.5% from infants, 17.9% from young animals, 16.2% from foods and 3.4% from the associated environmental sources. These EAEC isolates, on further characterisation, revealed predominance of ‘atypical’ EAEC, with an isolation rate of 10.7% from infants, 15.1% from young animals, 16.2% from foods, and 3.4% from the associated environmental sources. On PFGE analysis, discrimination was evident within DEC pathotypes as 52 unique pulsotypes were
An RF driven H- source and a low energy beam injection system for RFQ operation

International Nuclear Information System (INIS)

Leung, K.N.; Bachman, D.A.; Chan, C.F.; McDonald, D.S.

1992-01-01

An RF driven H - source has been developed at LBL for use in the Superconducting Super Collider (SSC). To date, an H - current of ∼40 mA can be obtained from a 5.6-cm-diam aperture with the source operated at a pressure of about 12 m Torr and 50 kW of RF power. In order to match the accelerated H - beam into the SSC RFQ, a low-energy H - injection system has been designed. This injector produces an outgoing H - beam free of electron contamination, with small radius, large convergent angle and small projectional emittance
Rapid isolation of biomarkers for compound specific radiocarbon dating using high-performance liquid chromatography and flow injection analysis-atmospheric pressure chemical ionisation mass spectrometry

NARCIS (Netherlands)

Sinninghe Damsté, J.S.; Smittenberg, R.H.; Hopmans, E.C.; Schouten, S.

2002-01-01

Repeated semi-preparative normal-phase HPLC was performed to isolate selected biomarkers from sediment extracts for radiocarbon analysis. Flow injection analysis mass spectrometry was used for rapid analysis of collected fractions to evaluate the separation procedure, taking only 1 min per fraction.
Rapid isolation of biomarkers for compound specific radiocarbon dating using high-performance liquid chromatography and flow injection analysis-atmospheric pressure chemical ionisation mass spectrometry.

Science.gov (United States)

Smittenberg, Rienk H; Hopmans, Ellen C; Schouten, Stefan; Sinninghe Damsté, Jaap S

2002-11-29

Repeated semi-preparative normal-phase HPLC was performed to isolate selected biomarkers from sediment extracts for radiocarbon analysis. Flow injection analysis-mass spectrometry was used for rapid analysis of collected fractions to evaluate the separation procedure, taking only 1 min per fraction. In this way 100-1000 microg of glycerol dialkyl glycerol tetraethers, sterol fractions and chlorophyll-derived phytol were isolated from typically 100 g of marine sediment, i.e., in sufficient quantities for radiocarbon analysis, without significant carbon isotopic fractionation or contamination.

Production of neutralizing antisera against viral hemorrhagic septicemia (VHS) virus by intravenous injections of rabbits

DEFF Research Database (Denmark)

Olesen, Niels Jørgen; Lorenzen, Niels; LaPatra, S.E.

1999-01-01

Rabbit antisera against viral hemorrhagic septicemia virus (VHSV) produced by two immunization procedures were compared for neutralization and immunochemical properties against homologous and heterologous strains. The VHSV isolate used as the immunogen was a member of a serogroup not neutralized...... by previously available antisera. The results from this study suggested that frequent intravenous (IV) injections of rabbits with viral antigens were superior to adjuvant-mediated, combined subcutaneous and intraperitoneal (SC/IP) injections for the production of neutralizing antisera. All IV injected rabbits...... produced high neutralization titers against the homologous VHSV isolate but not against an isolate from a different serogroup. The SC/IP injected rabbits had no significant neutralization titers against either the homologous VHSV strain or two isolates of a heterologous VHSV strain. Sera from all injected...
Effect of growth condition on biofilm formation by phenoldegrading bacteria isolated from polluted and nonpolluted sources

Directory of Open Access Journals (Sweden)

Arifah Khusnuryani

2015-03-01

Full Text Available Our previous research have isolated four phenol degrading bacteria. There are ATA6, DOK135, and DL120 which isolated from polluted source (hospital wastewater, also HP3 which isolated from non polluted source (peat soil. The purpose of this research is to analyze the effect of some environmental factors on the ability of four isolates to form biofilm. The environment factors were varied, such as growth medium, incubation temperature, and medium pH. Biofilm formation was measured using microtiter plate and crystal violet method, and the absorbance was read with microtiter auto reader at wavelenght 490 nm. The result showed that ATA6 was a strong biofilm former, DOK135 and HP3 were moderate biofilm former, and DL120 was a weak biofilm former. The results indicate that there is variation in the ability of selected isolates to form biofilm on various environmental factors. Generally, the isolates formed thicker biofilm in TSB medium which is a complex medium that provide more complete nutrient and formed biofilm optimally at 30oC. ATA6 formed biofilm optimally at pH 7 and HP3 at pH 9, while pH treatment did not affect on isolates DOK135 and DL120 to form biofilm.
The new injection beamline at VERA

International Nuclear Information System (INIS)

Priller, Alfred; Melber, Karl; Forstner, Oliver; Golser, Robin; Kutschera, Walter; Steier, Peter; Wallner, Anton

2010-01-01

VERA has been operated for 12 years with one 40-cathode SNICS ion source. Since the number of isotopes investigated at VERA increased steadily, we decided to install a second ion source. Due to space restrictions, a new injection line had to be built and merged into the existing one. The major task was to build an electrostatic analyzer assembly to accommodate injection from two ion sources.
Characteristics of a long-pulse (30-s), high-power (4-MW) ion source for neutral beam injection

International Nuclear Information System (INIS)

Menon, M.M.; Barber, G.C.; Combs, S.K.

1983-01-01

A quasi-steady-state ion source has been developed for neutral beam injection applications. It is of the duoPIGatron type designed for delivering 50 A of hydrogen ions at 80 keV for 30-s-long pulses. Ion beams of 40 A at 75 keV were extracted for pulse lengths up to 30 s, maintaining excellent optical quality in the beam for the entire pulse duration. The design features and operational characteristics of the ion source are elaborated
Genetic relatedness of Legionella longbeachae isolates from human and environmental sources in Australia

International Nuclear Information System (INIS)

Lanser, J.A.; Doyle, R.; Sangster, N.; Steele, T.W.; Adams, M.

1990-01-01

The genetic relatedness of Legionella longbeachae isolated in Australia since 1987 was investigated by restriction fragment length polymorphism (RFLP) analysis and allozyme electrophoresis. Three radiolabeled probes were used in Southern hybridizations for the RFLP studies. They were Escherichia coli 16S and 23S rRNA and cloned fragments of L. longbeachae selected empirically from genomal banks in lambda and a cosmid. The legionellae included in the study comprised 11 Legionella longbeachae serogroup 1 organisms isolated form humans, 28 L. longbeachae serogroup 1 isolates from environmental sources, 3 L. longbeachae serogroup 2 environmental isolates. These were compared with the American Type Culture Collection reference strains of both serogroups and some other related Legionella species. Results of allozyme and RFLP analysis showed that all the isolates from humans and all but three of the environmental L. longbeachae serogroup 1 isolates were closely related. They were also closely related to L. longbeachae serogroup 1 ATCC 33462. There was wider variation among the three L. longbeachae serogroup 2 environmental isolates. One of these was closely related to L. longbeachae serogroup 2 ATCC 33484. RFLP studies with the rRNA probe provided the most discrimination among isolates but did not distinguish between the two serogroups
Production of accelerated electrons near an electron source in the plasma resonance region

International Nuclear Information System (INIS)

Fedorov, V.A.

1989-01-01

Conditions of generation of plasma electrons accelerated and their characteristics in the vicinity of an electron source are determined. The electron source isolated electrically with infinitely conducting surface, being in unrestricted collisionless plasma ω 0 >>ν, where ω 0 - plasma frequency of nonperturbated plasma, ν - frequency of plasma electron collisions with other plasma particles, is considered. Spherically symmetric injection of electrons, which rates are simulated by ω frequency, occurs from the source surface. When describing phenomena in the vicinity of the electron source, one proceeds from the quasihydrodynamic equation set
Antibiotic susceptibility profiling and virulence potential of Campylobacter jejuni isolates from different sources in Pakistan.

Science.gov (United States)

Siddiqui, Fariha Masood; Akram, Muhammad; Noureen, Nighat; Noreen, Zobia; Bokhari, Habib

2015-03-01

To determine antibiotic resistance patterns and virulence potential of Campylobacter jejuni (C. jejuni) isolates from clinical human diarrheal infections, cattle and healthy broilers. Antibiotic sensitivity patterns of C. jejuni isolates were determined by Kirby Bauer Disc Diffusion assay. These isolates were then subjected to virulence profiling for the detection of mapA (membrane-associated protein), cadF (fibronectin binding protein), wlaN (beta-l,3-galactosyltransferase) and neuAB (sialic acid biosynthesis gene). Further C. jejuni isolates were grouped by random amplification of polymorphic DNA (RAPD) profiling. A total of 436 samples from poultry (n=88), cattle (n=216) and humans (n=132) from different locations were collected. Results revealed percentage of C. jejuni isolates were 35.2% (31/88), 25.0% (54/216) and 11.3% (15/132) among poultry, cattle and clinical human samples respectively. Antibiotic susceptibility results showed that similar resistance patterns to cephalothin was ie. 87.0%, 87.1% and 89%among humans, poultry and cattle respectively, followed by sulfamethoxazole+trimethoprim 40.0%, 38.7% and 31.0% in humans, poultry and cattle and Ampicillin 40%, 32% and 20% in humans, poultry and cattle respectively. Beta-lactamase activity was detected in 40.00% humans, 20.37% cattle and 32.25% in poultry C. jejuni isolates. CadF and mapA were present in all poultry, cattle and human C. jejuni isolates, wlaN was not detected in any isolate and neuAB was found in 9/31 (36%) poultry isolates. RAPD profiling results suggested high diversity of C. jejuni isolates. Detection of multidrug resistant C. jejuni strains from poultry and cattle is alarming as they can be potential hazard to humans. Moreover, predominant association of virulence factors, cadF and mapA (100% each) in C. jejuni isolates from all sources and neuAB (36%) with poultry isolates suggest the potential source of transmission of diverse types of C. jejuni to humans. Copyright © 2015 Hainan
Precipitation regions on the Earth of high energy electrons, injected by a point source moving along a circular Earth orbit

Science.gov (United States)

Kolesnikov, E. K.; Klyushnikov, G. N.

2018-05-01

In the paper we continue the study of precipitation regions of high-energy charged particles, carried out by the authors since 2002. In contrast to previous papers, where a stationary source of electrons was considered, it is assumed that the source moves along a low circular near-earth orbit with a constant velocity. The orbit position is set by the inclination angle of the orbital plane to the equatorial plane and the longitude of the ascending node. The total number of injected electrons is determined by the source strength and the number of complete revolutions that the source makes along the circumference. Construction of precipitation regions is produced using the computational algorithm based on solving of the system of ordinary differential equations. The features of the precipitation regions structure for the dipole approximation of the geomagnetic field and the symmetrical arrangement of the orbit relative to the equator are noted. The dependencies of the precipitation regions on different orbital parametres such as the incline angle, the ascending node position and kinetic energy of injected particles have been considered.
Commissioning and Operation of the FNAL Front end Injection Line and Ion Sources.

Energy Technology Data Exchange (ETDEWEB)

Karns, Patrick R. [Indiana Univ., Bloomington, IN (United States)

2015-09-01

This thesis documents the efforts made in commissioning and operating the RFQ Injection Line (RIL) as a replacement for the Cockcroft Walton front end. The Low Energy Beam Transport (LEBT) was assembled and tested with multiwire position and emittance monitor measurements. The Radio Frequency Quadrupole (RFQ) commissioning was completed with the same measurements as well as output beam energy measurements that showed it initially accelerated beam only to 700 keV, which was 50 keV lower than the design energy. Working with the manufacturer solutions were found and instituted to continue testing. The Medium Energy Beam Transport (MEBT) was then connected as the RIL was installed as the new front end of Linac. Testing gave way to operation when the new front end was used as the source of all High Energy Physics (HEP) beam for Fermi National Accelerator Laboratory (FNAL). The magnetron ion source that provides the H- beam for the front end required several changes and eventual upgrades to operate well; such as new source operating points for vacuum pressure and cesium admixture, and new materials for critical source components. Further research was conducted on the cathode geometry and nitrogen doping of the hydrogen gas as well as using solid state switches for the extractor system high voltage.
Characterization of Staphylococcus aureus isolates from raw milk sources in Victoria, Australia.

Science.gov (United States)

McMillan, Kate; Moore, Sean C; McAuley, Catherine M; Fegan, Narelle; Fox, Edward M

2016-07-29

Highly pathogenic strains of Staphylococcus aureus can cause disease in both humans and animals. In animal species, including ruminants, S. aureus may cause severe or sub-clinical mastitis. Dairy animals with mastitis frequently shed S. aureus into the milk supply which can lead to food poisoning in humans. The aim of this study was to use genotypic and immunological methods to characterize S. aureus isolates from milk-related samples collected from 7 dairy farms across Victoria. A total of 30 S. aureus isolates were collected from milk and milk filter samples from 3 bovine, 3 caprine and 1 ovine dairy farms across Victoria, Australia. Pulsed Field Gel Electrophoresis (PFGE) identified 11 distinct pulsotypes among isolates; all caprine and ovine isolates shared greater than 80 % similarity regardless of source. Conversely, bovine isolates showed higher diversity. Multi-Locus Sequence Typing (MLST) identified 5 different sequence types (STs) among bovine isolates, associated with human or ruminant lineages. All caprine and ovine isolates were ST133, or a single allele variant of ST133. Two new novel STs were identified among isolates in this study (ST3183 and ST3184). With the exception of these 2 new STs, eBURST analysis predicted all other STs to be founding members of their associated clonal complexes (CCs). Analysis of genetic markers revealed a diverse range of classical staphylococcal enterotoxins (SE) among isolates, with 11 different SEs identified among bovine isolates, compared with just 2 among caprine and ovine isolates. None of the isolates contained mecA, or were resistant to oxacillin. The only antibiotic resistance identified was that of a single isolate resistant to penicillin; this isolate also contained the penicillin resistance gene blaZ. Production of SE was observed at 16 °C and/or 37 °C in milk, however no SE production was detected at 12 °C. Although this study characterized a limited number of isolates, bovine-associated isolates
Isolation of hydrocarbon utilizing bacteria from different ecological sources

International Nuclear Information System (INIS)

Iqbal, M.J.; Choudri, S.F.; Hameed, A.

1991-01-01

Among the various samples from different ecological sources oil contaminated soil samples and waste from sugar processing industry were found to have bacterial populations with ability of utilizing oil. In addition to oil, molasses base medium was also used to study the utilizing ability. Selection was made on the basis on the high gas production, decrease in pH, percentage of oil consumed and bacterial counts. Fermented scum and oil contaminated soil from Sehala (Islamabad) were found to contain microbes having maximum oil degrading ability. The bacterial isolates belong to the genera of Bacillus, Pseudomonas, Enterobacter and Escherichia. (author)
Y-source impedance-network-based isolated boost DC/DC converter

DEFF Research Database (Denmark)

Siwakoti, Yam P.; Town, Graham; Loh, Poh Chiang

2014-01-01

A dc-dc converter with very high voltage gain is proposed in this paper for any medium-power application requiring a high voltage boost with galvanic isolation. The proposed converter topology can be realized using only two switches. With this topology a very high voltage boost can be achieved even...... with a relatively low duty cycle of the switches, and the gain obtainable is presently not matched by any existing impedance network based converter operated at the same duty ratio. The proposed converter has a Y-source impedance network to boost the voltage at the intermediate dc-link side and a push......-pull transformer for square-wave AC inversion and isolation. The voltage-doubler rectifier provides a constant dc voltage at the output stage. A theoretical analysis of the converter is presented, supported by simulation and experimental results. A 250 W down-scaled prototype was implemented in the laboratory...
Antimicrobial resistance of Aeromonas hydrophila isolated from different food sources: A mini-review

Directory of Open Access Journals (Sweden)

Deyan Stratev

2016-09-01

Full Text Available Summary: Aeromonas hydrophila is a Gram-negative, oxidase-positive, facultative, anaerobic, opportunistic aquatic pathogen. A. hydrophila produces virulence factors, such as hemolysins, aerolysins, adhesins, enterotoxins, phospholipase and lipase. In addition to isolation from aquatic sources, A. hydrophila has been isolated from meat and meat products, milk and dairy products, and vegetables. However, various studies showed that this opportunistic pathogen is resistant to commercial antibiotics. This is attributed to factors such as the indiscriminate use of antibiotics in aquaculture, plasmids or horizontal gene transfer. In this report, we highlight the occurrence, prevalence and antimicrobial resistance of A. hydrophila isolated from different food samples. The presence of antimicrobial-resistant A. hydrophila in food poses threats to public and aquatic animal health. Keywords: A. hydrophila, Antimicrobial resistance, Microbial food safety
"Injection first": a unique group of injection drug users in Tijuana, Mexico.

Science.gov (United States)

Morris, Meghan D; Brouwer, Kimberly C; Lozada, Remedios M; Gallardo, Manuel; Vera, Alicia; Strathdee, Steffanie A

2012-01-01

Using baseline data from a study of injection drug users (IDUs) in Tijuana, Mexico (N = 1,052), we identified social and behavioral factors associated with injecting at the same age or earlier than other administration routes of illicit drug use (eg, "injection first") and examined whether this IDU subgroup had riskier drug using and sexual behaviors than other IDUs. Twelve-percent "injected first." Characteristics independently associated with a higher odds of "injection first" included being younger at first injection, injecting heroin as their first drug, being alone at the first injection episode, and having a sexual debut at the same age or earlier as when they initiated drug use; family members' illicit drug use was associated with lower odds of injecting first. When adjusting for age at first injection and number of years injecting, "injection first" IDUs had lower odds of ever overdosing, and ever trading sex. On the other hand, they were less likely to have ever been enrolled in drug treatment, and more commonly obtained their syringes from potentially unsafe sources. In conclusion, a sizable proportion of IDUs in Tijuana injected as their first drug using experience, although evidence that this was a riskier subgroup of IDUs was inconclusive. Copyright © American Academy of Addiction Psychiatry.
Comparison of Campylobacter jejuni isolates from human, food, veterinary and environmental sources in Iceland using PFGE, MLST and fla-SVR sequencing.

Science.gov (United States)

Magnússon, S H; Guðmundsdóttir, S; Reynisson, E; Rúnarsson, A R; Harðardóttir, H; Gunnarson, E; Georgsson, F; Reiersen, J; Marteinsson, V Th

2011-10-01

Campylobacter jejuni isolates from various sources in Iceland were genotyped with the aim of assessing the genetic diversity, population structure, source distribution and campylobacter transmission routes to humans. A collection of 584 Campylobacter isolates were collected from clinical cases, food, animals and environment in Iceland in 1999-2002, during a period of national Campylobacter epidemic in Iceland. All isolates were characterized by pulse field gel electrophoresis (PFGE), and selected subset of 52 isolates representing the diversity of the identified PFGE types was further genotyped using multilocus sequence typing (MLST) and fla-SVR sequencing to gain better insight into the population structure. The results show a substantial diversity within the Icelandic Campylobacter population. Majority of the human Campylobacter infections originated from domestic chicken and cattle isolates. MLST showed the isolates to be distributed among previously reported and common sequence type complexes in the MLST database. The genotyping of Campylobacter from various sources has not previously been reported from Iceland, and the results of the study gave a valuable insight into the population structure of Camp. jejuni in Iceland, source distribution and transmission routes to humans. The geographical isolation of Iceland in the north Atlantic provides new information on Campylobacter population dynamics on a global scale. Journal of Applied Microbiology © 2011 The Society for Applied Microbiology No claim to Icelandic Government works.
Anticipated transient without scram analysis of the simplified boiling water reactor following main steam isolation valve closure with boron injection

International Nuclear Information System (INIS)

Khan, H.J.; Cheng, H.S.; Rohatgi, U.S.

1996-01-01

The simplified boiling water reactor (SBWR) operating in natural circulation is designed with many passive safety features. An anticipated transient without scram (ATWS) initiated by inadvertent closure of the main steam isolation valve (MSIV) in an SBWR has been analyzed using the RAMONA-4B code of Brookhaven National Laboratory. This analysis demonstrates the predicted performance of the SBWR during an MSIV closure ATWS, followed by shutdown of the reactor through injection of boron into the reactor core from the standby liquid control system
Molecular dynamics simulation of chemical vapor deposition of amorphous carbon. Dependence on H/C ratio of source gas

International Nuclear Information System (INIS)

Ito, Atsushi M.; Takayama, Arimichi; Nakamura, Hiroaki; Saito, Seiki; Ohno, Noriyasu; Kajita, Shin

2011-01-01

By molecular dynamics simulation, the chemical vapor deposition of amorphous carbon onto graphite and diamond surfaces was studied. In particular, we investigated the effect of source H/C ratio, which is the ratio of the number of hydrogen atoms to the number of carbon atoms in a source gas, on the deposition process. In the present simulation, the following two source gas conditions were tested: one was that the source gas was injected as isolated carbon and hydrogen atoms, and the other was that the source gas was injected as hydrocarbon molecules. Under the former condition, we found that as the source H/C ratio increases, the deposition rate of carbon atoms decreases exponentially. This exponential decrease in the deposition rate with increasing source H/C ratio agrees with experimental data. However, under the latter molecular source condition, the deposition rate did not decrease exponentially because of a chemical reaction peculiar to the type of hydrocarbon in the source gas. (author)
Review of ISOL target-ion-source systems

CERN Document Server

Kirchner, R

2003-01-01

Any review of target-ion-source systems (TISS) is necessarily a variation of the ISOL-theme 'efficient, fast, selective'. In the first part, more than 30 years of TISS development are examined in view of these key characteristics. By looking at the lines of development that were successful, at the lines that were abandoned (partly for good, partly for less good reasons), the lines with the most promising perspectives emerge. The second part deals with on-line chemistry in the TISS and its possibly double benefits: enhanced selectivity or increased separation speed, or both in favourable cases, as the relatively new sulfide chemistry. For the group-IVa-elements germanium and tin, the separation as sulfide-ions does not only suppress strongly the contamination by the neighbouring elements. It also reduces the effusion part of the release by orders of magnitude to the level of the intrinsic delay caused by molecular flow. The homologue chemistry is likely to work for silicon, but not for lead. While selectivity ...
Antibiotic susceptibility profile of bacteria isolated from natural sources of water from rural areas of East Sikkim

Directory of Open Access Journals (Sweden)

Shubra Poonia

2014-01-01

Full Text Available Background: Contamination of water, food, and environment with antibiotic-resistant bacteria poses a serious public health issue. Objective: The objective was to study the bacterial pollution of the natural sources of water in east Sikkim and to determine the antimicrobial profile of the bacterial isolates. Materials and Methods: A total of 225 samples, 75 each during winter, summer, and monsoon season were collected from the same source in every season for bacteriological analysis by membrane filtration method. Antibiotic susceptibility test was performed using standard disc diffusion method. Results: A total of 19 bacterial species of the genera Escherichia, Klebsiella, Proteus, Salmonella, Shigella, Enterobacter, Citrobacter, Morganella, Pseudomonas, Acinetobacter, Flavobacterium, and Serratia were isolated and their antimicrobial sensitivity tested. Generally, most bacterial isolates except Salmonella and Shigella species were found resistant to commonly used antibiotics such as ampicillin (57.5%, trimethoprim/sulfamethoxaole (39.1%, amoxicillin/clavulanic acid (37.4%, cefixime (34.5%, tetracycline (29.1%, ceftazidime (26.3%, ofloxacin (25.9%, amikacin (8.7%, and gentamicin (2.7% but sensitive to imipenem and piperacillin/tazobactam. Conclusion: Natural sources of water in east Sikkim are grossly contaminated with bacteria including enteropathogens. The consumption of untreated water from these sources might pose health risk to consumers.
Application of the guiding centre approximation to the transport of injected fast ions in a mirror based plasma neutron source

International Nuclear Information System (INIS)

Kumpf, H.; Noack, K.

1996-01-01

The guiding centre approximation for the motion of charged particles in axially symmetric magnetic and electric fields is formulated and stopping as well as small angle scattering on a multicomponent plasma are included. The developed code has been applied to the design of a 14-MeV neutron source according to the concept of the Budker Institute Novosibirsk. It is demonstrated that the self-interaction of injected D and T ions by stopping, scattering and induced internal fields has to be taken into account, if the injected power exceeds a few megawatt. (orig.)

Cryptococcus gattii VGIII isolates causing infections in HIV/AIDS patients in Southern California: identification of the local environmental source as arboreal.

Directory of Open Access Journals (Sweden)

Deborah J Springer

2014-08-01

Full Text Available Ongoing Cryptococcus gattii outbreaks in the Western United States and Canada illustrate the impact of environmental reservoirs and both clonal and recombining propagation in driving emergence and expansion of microbial pathogens. C. gattii comprises four distinct molecular types: VGI, VGII, VGIII, and VGIV, with no evidence of nuclear genetic exchange, indicating these represent distinct species. C. gattii VGII isolates are causing the Pacific Northwest outbreak, whereas VGIII isolates frequently infect HIV/AIDS patients in Southern California. VGI, VGII, and VGIII have been isolated from patients and animals in the Western US, suggesting these molecular types occur in the environment. However, only two environmental isolates of C. gattii have ever been reported from California: CBS7750 (VGII and WM161 (VGIII. The incongruence of frequent clinical presence and uncommon environmental isolation suggests an unknown C. gattii reservoir in California. Here we report frequent isolation of C. gattii VGIII MATα and MATa isolates and infrequent isolation of VGI MATα from environmental sources in Southern California. VGIII isolates were obtained from soil debris associated with tree species not previously reported as hosts from sites near residences of infected patients. These isolates are fertile under laboratory conditions, produce abundant spores, and are part of both locally and more distantly recombining populations. MLST and whole genome sequence analysis provide compelling evidence that these environmental isolates are the source of human infections. Isolates displayed wide-ranging virulence in macrophage and animal models. When clinical and environmental isolates with indistinguishable MLST profiles were compared, environmental isolates were less virulent. Taken together, our studies reveal an environmental source and risk of C. gattii to HIV/AIDS patients with implications for the >1,000,000 cryptococcal infections occurring annually for which
Metabolic variations of fatty acid in isolated rat heart reperfused after a transient global ischemia

International Nuclear Information System (INIS)

Huang Gang; Michel Comet; Zhao Huiyang; Zhu Cuiying; Yuan Jimin

1998-01-01

Purpose: The fatty acid metabolism and the effect of glucose on it were studied in isolated and reperfused rat heat. Methods: 32 isolated working rat hearts were perfused in Langengdorff device with modified Krebs and were divided into normal and ischemia-reperfused group. Each group was also classified into two subgroups, modified krebs with or without glucose subgroup. 131 I-HA was injected into aorta of isolated working rat heart and then the radio-residue curves were acquired. Results: When the isolated rat hearts were perfused with krebs plus glucose, the catabolism of fatty acid was significantly decreased in normal group, but a remarkable increase of fatty acid catabolism was found in ischemia-reperfused group. While the isolated rat hearts were perfused with krebs without glucose, the catabolism of fatty acid in ischemia-reperfused isolated rat hearts were perfused with krebs without glucose, the catabolism of fatty acid in ischemia-reperfused isolated rat heart was less than that in normal group. Conclusions: Transient ischemia damages the catabolism of myocardial fatty acid in mitochondria in some degree. In normal isolated working rat heart, the principal energy source is glucose. However, the major energy source is switched to catabolism of fatty acid in ischemia-reperfused isolated rat heart. This phenomenon may be related to compensative increase of fatty acid catabolism for replenishing the loss of energy during ischemia
Determination of the effective source of particles associated with pellet injection. Application to ITER

International Nuclear Information System (INIS)

Nehme, H.

2009-11-01

The determination of the effective source of particle associated with the injection of a pellet requires a thorough description of both pellet ablation and deposited material homogenization. The goal of this report is the description of such a study. In the first part, which is devoted to ablation physics, we first analyze the relative importance of the different processes shielding the pellet against the plasma heat flux, then present an attempt for validating the calculation of the over-ablation due to the suprathermal ion tail generated by the discharge heating systems and then estimate the influence of the initial shape of the pellet on the ablation rate. In the second part, which is devoted to the description of the drift of the pellet deposited material down the magnetic field gradient, we present a critical review of the drift models available up to now, then compare the measured characteristics of deposition profiles to our own simulations, showing a good agreement. This was done for data originating from different machines. Then, we describe the several improvements brought to our model and demonstrate - which is new, that there is a correlation between the location of the maximum of matter deposition and that of integer (and/or half-integer) q-surfaces. It must be noted that the underlying process is intrinsic to our modeling and that our calculations reproduce reasonably well the observed correlation for both the LFS (Low Field Side) and HFS (High Field Side) pellet data bases of Tore Supra and DIII-D. The last part reports on the modeling of pellet injection in ITER. First, from the present design of the pellet injection system, we estimate the expected deposition depth of the pellet material (ρ/a ∼ 0.85) and the flux to be injected for pacing the ELMs (Edge Localized Mode) and maintaining the core density (between 150 and 200 Pam 3 s -1 ). Then, we present a parametric study demonstrating that it is not possible to improve significantly the fuelling
Operating characteristics of a new ion source for KSTAR neutral beam injection system.

Science.gov (United States)

Kim, Tae-Seong; Jeong, Seung Ho; Chang, Doo-Hee; Lee, Kwang Won; In, Sang-Ryul

2014-02-01

A new positive ion source for the Korea Superconducting Tokamak Advanced Research neutral beam injection (KSTAR NBI-1) system was designed, fabricated, and assembled in 2011. The characteristics of the arc discharge and beam extraction were investigated using hydrogen and helium gas to find the optimum operating parameters of the arc power, filament voltage, gas pressure, extracting voltage, accelerating voltage, and decelerating voltage at the neutral beam test stand at the Korea Atomic Energy Research Institute in 2012. Based on the optimum operating condition, the new ion source was then conditioned, and performance tests were primarily finished. The accelerator system with enlarged apertures can extract a maximum 65 A ion beam with a beam energy of 100 keV. The arc efficiency and optimum beam perveance, at which the beam divergence is at a minimum, are estimated to be 1.0 A/kW and 2.5 uP, respectively. The beam extraction tests show that the design goal of delivering a 2 MW deuterium neutral beam into the KSTAR Tokamak plasma is achievable.
Energetic electron injections and dipolarization events in Mercury's magnetotail: Substorm dynamics

Science.gov (United States)

Dewey, R. M.; Slavin, J. A.; Raines, J. M.; Imber, S.; Baker, D. N.; Lawrence, D. J.

2017-12-01

Despite its small size, Mercury's terrestrial-like magnetosphere experiences brief, yet intense, substorm intervals characterized by features similar to at Earth: loading/unloading of the tail lobes with open magnetic flux, dipolarization of the magnetic field at the inner edge of the plasma sheet, and, the focus of this presentation, energetic electron injection. We use the Gamma-Ray Spectrometer's high-time resolution (10 ms) energetic electron measurements to determine the relationship between substorm activity and energetic electron injections coincident with dipolarization fronts in the magnetotail. These dipolarizations were detected on the basis of their rapid ( 2 s) increase in the northward component of the tail magnetic field (ΔBz 30 nT), which typically persists for 10 s. We estimate the typical flow channel to be 0.15 RM, planetary convection speed of 750 km/s, cross-tail potential drop of 7 kV, and flux transport of 0.08 MWb for each dipolarization event, suggesting multiple simultaneous and sequential dipolarizations are required to unload the >1 MWb of magnetic flux typically returned to the dayside magnetosphere during a substorm interval. Indeed, while we observe most dipolarization-injections to be isolated or in small chains of events (i.e., 1-3 events), intervals of sawtooth-like injections with >20 sequential events are also present. The typical separation between dipolarization-injection events is 10 s. Magnetotail dipolarization, in addition to being a powerful source of electron acceleration, also plays a significant role in the substorm process at Mercury.
Determination of the effective source of particles associated with pellet injection. Application to ITER; Calcul de la source de matiere effective associee a l'alimentation par injection de glacon. Application a ITER

Energy Technology Data Exchange (ETDEWEB)

Nehme, H.

2009-11-15

The determination of the effective source of particle associated with the injection of a pellet requires a thorough description of both pellet ablation and deposited material homogenization. The goal of this report is the description of such a study. In the first part, which is devoted to ablation physics, we first analyze the relative importance of the different processes shielding the pellet against the plasma heat flux, then present an attempt for validating the calculation of the over-ablation due to the suprathermal ion tail generated by the discharge heating systems and then estimate the influence of the initial shape of the pellet on the ablation rate. In the second part, which is devoted to the description of the drift of the pellet deposited material down the magnetic field gradient, we present a critical review of the drift models available up to now, then compare the measured characteristics of deposition profiles to our own simulations, showing a good agreement. This was done for data originating from different machines. Then, we describe the several improvements brought to our model and demonstrate - which is new, that there is a correlation between the location of the maximum of matter deposition and that of integer (and/or half-integer) q-surfaces. It must be noted that the underlying process is intrinsic to our modeling and that our calculations reproduce reasonably well the observed correlation for both the LFS (Low Field Side) and HFS (High Field Side) pellet data bases of Tore Supra and DIII-D. The last part reports on the modeling of pellet injection in ITER. First, from the present design of the pellet injection system, we estimate the expected deposition depth of the pellet material (rho/a approx 0.85) and the flux to be injected for pacing the ELMs (Edge Localized Mode) and maintaining the core density (between 150 and 200 Pam{sup 3}s{sup -1}). Then, we present a parametric study demonstrating that it is not possible to improve significantly
Plasma injection from the independent SHF-source in the open configuration 2. Magnetic fields of magnetic mirror configurations

International Nuclear Information System (INIS)

Beriya, Z.R.; Gogashvili, G.E.; Nanobashvili, S.I.

1992-01-01

The investigation was aimed at studying the characteristics and properties of plasma injected from independent stationary SHF source into an open magnetic trap of mirror geometry within a wide range of change in the experimental conditions. The investigations were primarily based on measurements of the distribution of charged particles in a plasma along the trap and on the dependence of the concentration on plasma production conditions in a SHF source. It is shown that the aggregate of the experimental data enables a conclusion that independent of SHF plasma can be succesfully used for filling on open magnetic trap of mirror configuration with plasma
Antimicrobial Activity of Carbon Nanoparticles Isolated from Natural Sources against Pathogenic Gram-Negative and Gram-Positive Bacteria

International Nuclear Information System (INIS)

Varghese, S.; Jose, S.; Varghese, S.; Kuriakose, S.; Jose, S.

2013-01-01

This paper describes the isolation of carbon nanoparticles (CNPs) from kitchen soot, characterization of the CNPs by UV/visible spectroscopy, SEM and XRD, and their antimicrobial action. The antibacterial activity of the isolated carbon nanoparticles was tested against various pathogenic bacterial strains such as Gram-negative Proteus refrigere and Pseudomonas aeruginosa and Gram-positive Staphylococcus aureus and Streptococcus haemolyticus. The inhibition zones were measured, and it was found that the carbon nanoparticles isolated from natural sources are active against these Gram-negative and Gram-positive bacterial strains
Glycerol as a carbon source for xantan production by Xanthomonas campestris isolates

Directory of Open Access Journals (Sweden)

Bajić Bojana Ž.

2015-01-01

Full Text Available The success of xanthan biosynthesis depends on several factors, most importantly the genetic potential of the production microorganism and cultivation media composition. Cultivation media composition affects the yield and quality of the desired product as well as production costs. This is why many studies focus on finding cheap alternative raw materials, especially carbon sources, to replace commercially used glucose and sucrose. In addition to the Xanthomonas campestris ATCC 13951 which is the primary industrial production microorganism, other Xanthomonas strains can produce xanthan as well. Under the same conditions, different strains produce different amounts of the biopolymer of varying quality. The aim of this paper is to compare producibility of phytopathogenic X. campestris strains, isolated from the environment with the reference X. campestris ATCC 13951 strain and to estimate the possibility of xanthan production using alternative glycerol-based media than the synthetic glucose-based media. Submerged cultivation on the medium based on glucose or glycerol (2.0 %w/v was performed using the reference strain and eight isolated X. campestris strains. In order to assess the success of biosynthesis, xanthan yield and rheological properties were determined. Strains isolated from the environment produced yields between 2.98 g/L and 12.17 g/L on the glucose-based medium and 1.68 g/L and 6.31 g/L on the glycerol-based medium. Additionally, X. campestris ATCC 13951 provided the highest yield when using glucose (13.24 g/L, as well as glycerol-based medium (7.44 g/L. The obtained results indicate that in the applied experimental conditions and using all tested strains, glycerol is viable as a carbon source for the production of xanthan.
Thermotolerant yeasts capable of producing bioethanol: isolation from natural fermented sources, identification and characterization

Directory of Open Access Journals (Sweden)

Ali Azam Talukder

2016-11-01

Full Text Available Recently, the demands of biofuels have increased, because of their significant role in reducing various pollutants created by fossil fuels. Here, we have collected 25 samples containing various thermotolerant microorganisms from the nine natural fermented sources of Bangladesh, such as Boiled potato (Bp, Decomposed foods (Df, Municipal liquid waste (Mlw, Municipal solid waste (Msw, Sugarcane juice (Sc, Pantavat (Pv, Sugar molasses (Sm, Tari (Tari and Watermelon juice (Wm for bioethanol production. Among them, 18 isolates are capable of producing bioethanol. Cultural, morphological, physiological, biochemical and genetic analyses were carried out under various physiological conditions. Ethanol fermentation was checked by different carbon sources, temperatures and pH. All of the isolates could grow well in the medium containing Dextrose and Arabinose and only two strains Pv-1 and Bp-2 could ferment Xylose as a sole carbon source. At 42 °C, the highest ethanol concentration 6.58% (v/v was obtained by a strain Wm-1 isolated from Watermelon juice. At 37 °C, maximal ethanol concentrations of 6.74% (v/v, 6.50% (v/v and 6.22% (v/v were obtained by the strains Bp-2, Wm-l and Pv-1, respectively. Among the various pH tested, the highest ethanol concentration 6.6% (v/v was obtained at pH 4.5 by a strain named Tari-2. Finally, yeast 26S rDNA sequencing information identified the strains Sc-2 as Saccharomyces cerevisiae Pv-2, Tari-2 and Df-1 as Pichia kudriavzevii, Mlw-l and Bp-2 as Candida tropicalis, Pv-1 as Pichia guilliermondii and Df-2 as Candida rugosa.
Rapid detection and E-test antimicrobial susceptibility testing of Vibrio parahaemolyticus isolated from seafood and environmental sources in Malaysia.

Science.gov (United States)

Al-Othrubi, Saleh M; Hanafiah, Alfizah; Radu, Son; Neoh, Humin; Jamal, Rahaman

2011-04-01

To find out the prevalence and antimicrobial susceptibility of Vibrio parahaemolyticus in seafoods and environmental sources. The study was carried out at the Center of Excellence for Food Safety Research, University Putra Malaysia; Universiti Kebangsaan Malaysia; Medical Molecular Biology Institute; and University Kebansaan Malaysia Hospital, Malaysia between January 2006 and August 2008. One hundred and forty-four isolates from 400 samples of seafood (122 isolates) and seawater sources (22 isolates) were investigated for the presence of thermostable direct hemolysin (tdh+) and TDH-related hemolysin (trh+) genes using the standard methods. The E-test method was used to test the antimicrobial susceptibility. The study indicates low occurrence of tdh+ (0.69%) and trh+ isolates (8.3%). None of the isolates tested posses both virulence genes. High sensitivity was observed against tetracycline (98%). The mean minimum inhibitory concentration (MIC) of the isolates toward ampicillin increased from 4 ug/ml in 2004 to 24 ug/ml in 2007. The current study demonstrates a low occurrence of pathogenic Vibrio parahaemolyticus in the marine environment and seafood. Nonetheless, the potential risk of vibrio infection due to consumption of Vibrio parahaemolyticus contaminated seafood in Malaysia should not be neglected.
Injection and lessons for 2012

International Nuclear Information System (INIS)

Bracco, C.; Barnes, M.J.; Bartmann, W.; Cornelis, K.; Drosdal, L.N.; Goddard, B.; Kain, V.; Meddahi, M.; Mertens, V.; Uythoven, J.

2012-01-01

Injection of 144 bunches into the LHC became fully operational during the 2011 run and one nominal injection of 288 bunches was accomplished. Several mitigation solutions were put in place to minimise losses from the Transfer Line (TL) collimators and losses from kicking de-bunched beam during injection. Nevertheless, shot-by- shot and bunch-by-bunch trajectory variations, as well as long terms drifts, were observed and required a regular re-steering of the TL implying a non negligible amount of time spent for injection setup. Likely sources of instability have been identified (i.e. MKE and MSE ripples) and possible cures to optimise 2012 operation are presented. Well defined references for TL steering will be defined in a more rigorous way in order to allow a more straightforward and faster injection setup. Encountered and potential issues of the injection system, in particular the injection kickers MKI, are discussed also in view of injections with a higher number of bunches. (authors)
Injection and lessons for 2012

CERN Document Server

Bracco, C; Bartmann, W; Cornelis, K; Drosdal, L N; Goddard, B; Kain, V; Meddahi, M; Mertens, V; Uythoven, J

2012-01-01

Injection of 144 bunches into the LHC became fully operational during the 2011 run and a nominal injection of 288 bunches was accomplished during MD time. Several mitigation solutions were put in place to minimise losses from the transfer line (TL) collimators and losses from kicking debunched beam during injection. Nevertheless, shot-by-shot and bunch-by-bunch trajectory variations, as well as long terms drifts, were observed and required a regular resteering of the TL implying a non negligible amount of time spent for injection setup. Likely sources of instability have been identified (i.e. MKE and MSE ripples) and possible cures to optimise 2012 operation are presented. Well defined references for TL steering will be defined in a more rigorous way in order to allow a more straightforward and faster injection setup. Encountered and potential issues of the injection system, in particular the injection kickers MKI, are discussed also in view of injections with a higher number of bunches.
Revised Earthquake Catalog and Relocated Hypocenters Near Fluid Injection Wells and the Waste Isolation Pilot Plant (WIPP) in Southeastern New Mexico

Science.gov (United States)

Edel, S.; Bilek, S. L.; Garcia, K.

2014-12-01

Induced seismicity is a class of crustal earthquakes resulting from human activities such as surface and underground mining, impoundment of reservoirs, withdrawal of fluids and gas from the subsurface, and injection of fluids into underground cavities. Within the Permian basin in southeastern New Mexico lies an active area of oil and gas production, as well as the Waste Isolation Pilot Plant (WIPP), a geologic nuclear waste repository located just east of Carlsbad, NM. Small magnitude earthquakes have been recognized in the area for many years, recorded by a network of short period vertical component seismometers operated by New Mexico Tech. However, for robust comparisons between the seismicity patterns and the injection well locations and rates, improved locations and a more complete catalog over time are necessary. We present results of earthquake relocations for this area by using data from the 3-component broadband EarthScope Flexible Array SIEDCAR experiment that operated in the area between 2008-2011. Relocated event locations tighten into a small cluster of ~38 km2, approximately 10 km from the nearest injection wells. The majority of events occurred at 10-12 km depth, given depth residuals of 1.7-3.6 km. We also present a newly developed more complete catalog of events from this area by using a waveform cross-correlation algorithm and the relocated events as templates. This allows us to detect smaller magnitude events that were previously undetected with the short period network data. The updated earthquake catalog is compared with geologic maps and cross sections to identify possible fault locations. The catalog is also compared with available well data on fluid injection and production. Our preliminary results suggest no obvious connection between seismic moment release, fluid injection, or production given the available monthly industry data. We do see evidence in the geologic and well data of previously unidentified faults in the area.
Draft Genome Sequences of 37 Salmonella enterica Strains Isolated from Poultry Sources in Nigeria.

Science.gov (United States)

Useh, Nicodemus M; Ngbede, Emmanuel O; Akange, Nguavese; Thomas, Milton; Foley, Andrew; Keena, Mitchel Chan; Nelson, Eric; Christopher-Hennings, Jane; Tomita, Masaru; Suzuki, Haruo; Scaria, Joy

2016-05-05

Here, we report the availability of draft genomes of several Salmonella serotypes, isolated from poultry sources from Nigeria. These genomes will help to further understand the biological diversity of S. enterica and will serve as references in microbial trace-back studies to improve food safety. Copyright © 2016 Useh et al.
Performance and emission studies on port injection of hydrogen with varied flow rates with Diesel as an ignition source

International Nuclear Information System (INIS)

Saravanan, N.; Nagarajan, G.

2010-01-01

Automobiles are one of the major sources of air pollution in the environment. In addition CO 2 emission, a product of complete combustion also has become a serious issue due to global warming effect. Hence the search for cleaner alternative fuels has become mandatory. Hydrogen is expected to be one of the most important fuels in the near future for solving the problems of air pollution and greenhouse gas problems (carbon dioxide), thereby protecting the environment. Hence in the present work, an experimental investigation has been carried out using hydrogen in the dual fuel mode in a Diesel engine system. In the study, a Diesel engine was converted into a dual fuel engine and hydrogen fuel was injected into the intake port while Diesel was injected directly inside the combustion chamber during the compression stroke. Diesel injected inside the combustion chamber will undergo combustion first which in-turn would ignite the hydrogen that will also assist the Diesel combustion. Using electronic control unit (ECU), the injection timings and injection durations were varied for hydrogen injection while for Diesel the injection timing was 23 o crank angle (CA) before injection top dead centre (BITDC). Based on the performance, combustion and emission characteristics, the optimized injection timing was found to be 5 o CA before gas exchange top dead centre (BGTDC) with injection duration of 30 o CA for hydrogen Diesel dual fuel operation. The optimum hydrogen flow rate was found to be 7.5 lpm. Results indicate that the brake thermal efficiency in hydrogen Diesel dual fuel operation increases by 15% compared to Diesel fuel at 75% load. The NO X emissions were higher by 1-2% in dual fuel operation at full load compared to Diesel. Smoke emissions are lower in the entire load spectra due to the absence of carbon in hydrogen fuel. The carbon monoxide (CO), carbon dioxide (CO 2 ) emissions were lesser in hydrogen Diesel dual fuel operation compared to Diesel. The use of hydrogen
Performance and emission studies on port injection of hydrogen with varied flow rates with Diesel as an ignition source

Energy Technology Data Exchange (ETDEWEB)

Saravanan, N. [ERC Engines, Tata Motors, Pimpri, Pune (India); Nagarajan, G. [Internal Combustion Engineering Division, Department of Mechanical Engineering, College of Engineering, Guindy, Anna University, Chennai (India)

2010-07-15

Automobiles are one of the major sources of air pollution in the environment. In addition CO{sub 2} emission, a product of complete combustion also has become a serious issue due to global warming effect. Hence the search for cleaner alternative fuels has become mandatory. Hydrogen is expected to be one of the most important fuels in the near future for solving the problems of air pollution and greenhouse gas problems (carbon dioxide), thereby protecting the environment. Hence in the present work, an experimental investigation has been carried out using hydrogen in the dual fuel mode in a Diesel engine system. In the study, a Diesel engine was converted into a dual fuel engine and hydrogen fuel was injected into the intake port while Diesel was injected directly inside the combustion chamber during the compression stroke. Diesel injected inside the combustion chamber will undergo combustion first which in-turn would ignite the hydrogen that will also assist the Diesel combustion. Using electronic control unit (ECU), the injection timings and injection durations were varied for hydrogen injection while for Diesel the injection timing was 23 crank angle (CA) before injection top dead centre (BITDC). Based on the performance, combustion and emission characteristics, the optimized injection timing was found to be 5 CA before gas exchange top dead centre (BGTDC) with injection duration of 30 CA for hydrogen Diesel dual fuel operation. The optimum hydrogen flow rate was found to be 7.5 lpm. Results indicate that the brake thermal efficiency in hydrogen Diesel dual fuel operation increases by 15% compared to Diesel fuel at 75% load. The NO{sub X} emissions were higher by 1-2% in dual fuel operation at full load compared to Diesel. Smoke emissions are lower in the entire load spectra due to the absence of carbon in hydrogen fuel. The carbon monoxide (CO), carbon dioxide (CO{sub 2}) emissions were lesser in hydrogen Diesel dual fuel operation compared to Diesel. The use of
Injecting Artificial Memory Errors Into a Running Computer Program

Science.gov (United States)

Bornstein, Benjamin J.; Granat, Robert A.; Wagstaff, Kiri L.

2008-01-01

Single-event upsets (SEUs) or bitflips are computer memory errors caused by radiation. BITFLIPS (Basic Instrumentation Tool for Fault Localized Injection of Probabilistic SEUs) is a computer program that deliberately injects SEUs into another computer program, while the latter is running, for the purpose of evaluating the fault tolerance of that program. BITFLIPS was written as a plug-in extension of the open-source Valgrind debugging and profiling software. BITFLIPS can inject SEUs into any program that can be run on the Linux operating system, without needing to modify the program s source code. Further, if access to the original program source code is available, BITFLIPS offers fine-grained control over exactly when and which areas of memory (as specified via program variables) will be subjected to SEUs. The rate of injection of SEUs is controlled by specifying either a fault probability or a fault rate based on memory size and radiation exposure time, in units of SEUs per byte per second. BITFLIPS can also log each SEU that it injects and, if program source code is available, report the magnitude of effect of the SEU on a floating-point value or other program variable.
TARA beamline and injection system

International Nuclear Information System (INIS)

Post, R.S.; Brindza, P.; Coleman, J.W.; Torti, R.P.; Blackfield, D.T.; Goodrich, P.

1983-01-01

The TARA beamline for neutral beam injection will permit one to three sources to fire into each plug (60 degree or optional 90 degree injection with respect to the TARA axis) or into each anchor (90 degree injection only). The sources, pre-aimed on their mounting plate at the NB test stand, may be fired into neutralizer ducts or optionally through a magnesium curtain, and the unneutralized fraction is dumped by the TARA fringing field onto a receiver plate. The beamline is housed in a cylindrical tank with the beam axis along the tank diameter at the midplane. The tank will be sorption pumped using LN + T/sub I/ or N/sub B/ and/or e-beam gettering. The beam burial tank contains sed arrays and a thin foil dump which reaches sufficiently high temperatures during the shot to boil out gas between shots
Investigating the Keratinolytic Activities of the Bacteria Isolated from Different Sources

Science.gov (United States)

Chen, S. X.

2017-12-01

Background InformationThe development of microbial keratinase has gained increasing attention over the million tons of keratinous wastes generated by the worldwide livestock population. Keratinous wastes not only serve as the niche for pathogenic microorganisms, but also they collapse environmental balance for being the source of air, soil, and water pollutions. Conversely, microbial keratinases can convert the unexploited keratinous wastes into bioaccessible animal feed. However, because of the recalcitrant structure of keratin, the complete keratin degradation is difficult to achieve with one keratinase as opposed to recombinant keratinases. Therefore, this study is designed to isolate the bacteria from different sources and to evaluate their keratinolytic activities using azokeratin substrates. Materials and Methods Soil, horse hooves, penguin stool, and chicken stool are collected from different sites. These samples are serially diluted and then streaked on feather-meal agar plates. Single colonies are screened for the ability to hydrolyze keratin. The isolate of single colonies is cultivated in a whole-feather medium. The sample is then centrifuged, and the supernatant is used for crude enzyme preparation. Azokeratin is synthesized by coupling bristle keratin with diazotized laurent's acid, and it is used as a substrate for assaying keratinase activity by using a spectrophotometer. ConclusionThis study will compare the keratinase activities on bristle azokeratin substrates from three different samples and thus evaluate the bacterium with the best ability to hydrolyze keratin amongst the three. Further steps will be taken to produce a blend of enzymes generated and select the optimum combination that can most efficiently degrade keratin.

Robust, open-source removal of systematics in Kepler data

Science.gov (United States)

Aigrain, S.; Parviainen, H.; Roberts, S.; Reece, S.; Evans, T.

2017-10-01

We present ARC2 (Astrophysically Robust Correction 2), an open-source python-based systematics-correction pipeline, to correct for the Kepler prime mission long-cadence light curves. The ARC2 pipeline identifies and corrects any isolated discontinuities in the light curves and then removes trends common to many light curves. These trends are modelled using the publicly available co-trending basis vectors, within an (approximate) Bayesian framework with 'shrinkage' priors to minimize the risk of overfitting and the injection of any additional noise into the corrected light curves, while keeping any astrophysical signals intact. We show that the ARC2 pipeline's performance matches that of the standard Kepler PDC-MAP data products using standard noise metrics, and demonstrate its ability to preserve astrophysical signals using injection tests with simulated stellar rotation and planetary transit signals. Although it is not identical, the ARC2 pipeline can thus be used as an open-source alternative to PDC-MAP, whenever the ability to model the impact of the systematics removal process on other kinds of signal is important.
Bioelectromagnetic forward problem: isolated source approach revis(it)ed.

Science.gov (United States)

Stenroos, M; Sarvas, J

2012-06-07

Electro- and magnetoencephalography (EEG and MEG) are non-invasive modalities for studying the electrical activity of the brain by measuring voltages on the scalp and magnetic fields outside the head. In the forward problem of EEG and MEG, the relationship between the neural sources and resulting signals is characterized using electromagnetic field theory. This forward problem is commonly solved with the boundary-element method (BEM). The EEG forward problem is numerically challenging due to the low relative conductivity of the skull. In this work, we revise the isolated source approach (ISA) that enables the accurate, computationally efficient BEM solution of this problem. The ISA is formulated for generic basis and weight functions that enable the use of Galerkin weighting. The implementation of the ISA-formulated linear Galerkin BEM (LGISA) is first verified in spherical geometry. Then, the LGISA is compared with conventional Galerkin and symmetric BEM approaches in a realistic 3-shell EEG/MEG model. The results show that the LGISA is a state-of-the-art method for EEG/MEG forward modeling: the ISA formulation increases the accuracy and decreases the computational load. Contrary to some earlier studies, the results show that the ISA increases the accuracy also in the computation of magnetic fields.
Isolation of whiskers from natural sources and their dispersed in a non-aqueous medium

Directory of Open Access Journals (Sweden)

Mauro Vestena

Full Text Available Abstract Whiskers have been used as a nanomaterial dispersed in polymer matrices to modify the microscopic and macroscopic properties of the polymer. These nanomaterials can be isolated from cellulose, one of the most abundant natural renewable sources of biodegradable polymer. In this study, whiskers were isolated from sugarcane bagasse and corn cob straw fibers. Initially, the cellulose fiber was treated through an alkaline/oxidative process followed by acid hydrolysis. Dimethylformamide and dimethyl sulfoxide were used to replace the aqueous medium for the dispersion of the whiskers. For the solvent exchange, dimethylformamide or dimethyl sulfoxide was added to the aqueous dispersion and the water was then removed by fractional distillation. FTIR, TGA, XRD, TEM, Zeta and DLS techniques were used to evaluate the efficiency of the isolation process as well as the morphology and dimensions of the whiskers. The dimensions of the whiskers are comparable with values reported in the literature, maintaining the uniformity and homogeneity in both aqueous and non-aqueous solvents.
Isolation of whiskers from natural sources and their dispersed in a non-aqueous medium

Energy Technology Data Exchange (ETDEWEB)

Vestena, Mauro; Gross, Idejan Padilha; Pires, Alfredo Tiburcio Nunes; Muller, Carmen Maria Olivera, E-mail: mauro@utfpr.edu.br [Universidade Federal Santa Catarina (UFSC), Florianopolis, SC (Brazil)

2016-10-15

Whiskers have been used as a nano material dispersed in polymer matrices to modify the microscopic and macroscopic properties of the polymer. These nanomaterials can be isolated from cellulose, one of the most abundant natural renewable sources of biodegradable polymer. In this study, whiskers were isolated from sugarcane bagasse and corn cob straw fibers. Initially, the cellulose fiber was treated through an alkaline/oxidative process followed by acid hydrolysis. Dimethylformamide and dimethyl sulfoxide were used to replace the aqueous medium for the dispersion of the whiskers. For the solvent exchange, dimethylformamide or dimethyl sulfoxide was added to the aqueous dispersion and the water was then removed by fractional distillation. FTIR, TGA, XRD, TEM, Zeta and DLS techniques were used to evaluate the efficiency of the isolation process as well as the morphology and dimensions of the whiskers. The dimensions of the whiskers are comparable with values reported in the literature, maintaining the uniformity and homogeneity in both aqueous and non-aqueous solvents. (author)
Pseudorandom binary injection of levitons for electron quantum optics

Science.gov (United States)

Glattli, D. C.; Roulleau, P.

2018-03-01

The recent realization of single-electron sources lets us envision performing electron quantum optics experiments, where electrons can be viewed as flying qubits propagating in a ballistic conductor. To date, all electron sources operate in a periodic electron injection mode, leading to energy spectrum singularities in various physical observables which sometimes hide the bare nature of physical effects. To go beyond this, we propose a spread-spectrum approach where electron flying qubits are injected in a nonperiodic manner following a pseudorandom binary bit pattern. Extending the Floquet scattering theory approach from periodic to spread-spectrum drive, the shot noise of pseudorandom binary sequences of single-electron injection can be calculated for leviton and nonleviton sources. Our new approach allows us to disentangle the physics of the manipulated excitations from that of the injection protocol. In particular, the spread-spectrum approach is shown to provide better knowledge of electronic Hong-Ou-Mandel correlations and to clarify the nature of the pulse train coherence and the role of the dynamical orthogonality catastrophe for noninteger charge injection.
Injection and extraction for cyclotrons

International Nuclear Information System (INIS)

Heikkinen, P.

1994-01-01

External ion sources for cyclotrons are needed for polarised and heavy ions. This calls for injection systems, either radial or axial. Radial injection is also needed when a cyclotron works as a booster after another cyclotron or a linear accelerator (usually tandem). Requirements for injection differ from separated sector cyclotrons where there is plenty of room to house inflectors and/or strippers, to superconducting cyclotrons where the space is limited by a small magnet gap, and high magnetic field puts other limitations to the inflectors. Several extraction schemes are used in cyclotrons. Stripping injection is used for H - and also for heavy ions where the q/m ratio is usually doubled. For other cases, electric and magnetic deflection has to be used. To increase the turn separation before the first deflector, both resonant and non-resonant schemes are used. In this lecture, external injection systems are surveyed and some rules to thumb for injection parameters are given. Extraction schemes are also reviewed. (orig.)
Water feeding method upon reactor isolation

International Nuclear Information System (INIS)

Sasaki, Koichi; Takahara, Kuniaki; Hamamura, Kenji; Arakawa, Masahiro.

1990-01-01

The present invention concerns a method of feeding water upon reactor isolation in a plural loop type reactor having a plurality of reactor cooling systems. Water can be injected to a plurality of pools even if the pressure between the pools is not balanced and the water level in the reactor cooling system is optimally controlled. That is, water can be injected in accordance with the amount required for each of the pools by setting the opening of a turbine inlet steam control valve to somewhat higher than the cooling system pressure of the highest pressure loop. Water feeding devices upon reactor isolation were required by the same number as that for the reactor cooling systems. Whereas since pumps and turbines are used in common without worsening the water injection controllability to each of the loops according to the method of this invention and, accordingly, the cost performance can be improved. Further, since the opening degree of the turbine inlet steam control valve is controlled while making the difference pressure constant between the turbine inlet pressure and the pump exhaust pressure, the amount of the turbine exhausted steams can be reduced and, further, water injection controllability of the flow rate control valve in the injection line is improved. (I.S.)
Feedback correction of injection errors using digital signal-processing techniques

Directory of Open Access Journals (Sweden)

N. S. Sereno

2007-01-01

Full Text Available Efficient transfer of electron beams from one accelerator to another is important for 3rd-generation light sources that operate using top-up. In top-up mode, a constant amount of charge is injected at regular intervals into the storage ring to replenish beam lost primarily due to Touschek scattering. Top-up therefore requires that the complex of injector accelerators that fill the storage ring transport beam with a minimum amount of loss. Injection can be a source of significant beam loss if not carefully controlled. In this note we describe a method of processing injection transient signals produced by beam-position monitors and using the processed data in feedback. Feedback control using the technique described here has been incorporated in the Advanced Photon Source (APS booster synchrotron to correct injection transients.
Enterococci Isolated from Cypriot Green Table Olives as a New Source of Technological and Probiotic Properties

Directory of Open Access Journals (Sweden)

Dimitrios A. Anagnostopoulos

2018-06-01

Full Text Available Τable olive is one of the main fermented vegetable worldwide and can be processed as treated or natural product. Lactic Acid Bacteria (LAB are responsible for the fermentation of treated olives. The aim of this work was to study the technological characteristics and the potential probiotic properties of LAB isolated from Cypriot green table olives. This is the first comprehensive report on the isolation and characterization of LAB isolates retrieved from Cypriot green table olives. From a collection of 92 isolates from spontaneously fermenting green olives, 64 g positive isolates were firstly identified to genus level using biochemical tests, and secondly to species level using multiplex species specific polymerase chain reaction (PCR amplifications of the sodA gene. Moreover, each of our isolates were tested for their technological and probiotics properties, as well as for their safety characteristics, using biochemical and molecular methods, in order to be used as starter cultures. Finally, to discriminate the most promising isolates on the base of their technological and probiotics properties, Principal component analysis was used. All the isolates were identified as Enteroccocus faecium, having interesting technological properties, while pathogenicity determinants were absent. Principal component analysis showed that some isolates had a combination of the tested parameters. These findings demonstrate that enteroccoci from Cypriot table olives should be considered as a new source of potential starter cultures for fermented products, having possibly promising technological and probiotic attributes.
Zinc injection on the EDF fleet monitoring the injection on 12 units

International Nuclear Information System (INIS)

Le-Meur, Gaelle Harmand; Anne-Marie; Stutzmann, Agnes; Taunier, Stephane; Benfarah, Moez; Bretelle, Jean-Luc; Alain, Rocher; Claeys, Myriam; Bonne, Sebastien

2012-09-01

After a first implementation of zinc injection at Bugey 2 and Bugey 4, EDF decided to extend the program to other units of its fleet. 14 more reactors from the French fleet of 58 were chosen in order to - Reduce the radiation sources for curative or preventive (after SGR) reasons - Mitigate stress corrosion cracking on nickel alloys and reduce the rate of generalized corrosion - Prevent the risk of CIPS, mainly after a fuel management change. Zinc injection started on 9 new units in 2011, 1 unit in 2012 and will be extended to 4 other units before the end of 2013. To monitor the injection, EDF has defined a complete program concerning chemistry, radiation protection (dose rate and deposited activities measurements), materials (statistical analysis of SG tube cracks), fuel (oxide measurements) and waste (radiochemical characterization of filters). Reference units were chosen for each field because of the size of the fleet. This paper will detail the different monitoring programs on the EDF plants injecting zinc. (authors)
Beam optics study of a negative ion source for neutral beam injection application at ASIPP

Energy Technology Data Exchange (ETDEWEB)

Wei, Jiang-Long; Liang, Li-Zhen [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Jiang, Cai-Chao [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Graduate school, University of Science and Technology of China, Hefei 230026 (China); Xie, Ya-Hong, E-mail: xieyh@ipp.ac.cn [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Hu, Chun-Dong; Li, Jun; Gu, Yu-Ming; Chen, Yu-Qian [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Li, Jing-Yong; Wu, Ming-Shan [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Graduate school, University of Science and Technology of China, Hefei 230026 (China)

2017-04-15

In order to study the generation and extraction of negative ions for neutral beam injection application, a negative ion source is being designed and constructed at Institute of Plasma Physics, Chinese Academy of Sciences (ASIPP). Through a four electrode grids system inside the accelerator, a negative ion beam will be extracted and accelerated up to −60 kV on a reduced scale extraction area of 12 × 50 cm{sup 2} (the area of PG apertures is 185 cm{sup 2}). The beam optics is a key issue for the accelerator design, and greatly determine the source experimental performance in term of beam current, heat load on the grid, beam divergence, and so on. In this paper, the trajectories of electrons and negative ions were simulated in the electrode grids of the negative ion source. The filter capability of electron deflection magnet on the co-extracted electrons is evaluated and confirmed. The negative ion beam optics was designed according to the calculated results of beam divergence and beam radius along the beamlet in different acceleration voltages. The deflection effect of the electron deflection magnet on the negative ion beam was investigated in the single beamlet case and multi-beamlets case.
Performance and emission study in manifold hydrogen injection with diesel as an ignition source for different start of injection

Energy Technology Data Exchange (ETDEWEB)

Saravanan, N. [ERC-Engines, TATA Motors Ltd, Pimpri, Pune, Maharashtra 411018 (India); Nagarajan, G. [Internal Combustion Engineering Division, Department of Mechanical Engineering, College of Engineering, Guindy, Anna University, Chennai, Tamil Nadu 600 025 (India)

2009-01-15

Over the past two decades there has been a considerable effort to develop and introduce alternative transportation fuels to replace conventional fuels, gasoline and diesel. Environmental issues are the principal driving forces behind this effort. To date the bulk of research has focused on the carbon-based fuels such as reformulated gasoline, methanol and natural gas. One alternative fuel to carbon-based fuels is hydrogen which is considered to be low polluting fuel. In the present experimental investigation hydrogen was injected into the intake manifold by using an injector. Using an electronic control unit (ECU) the injection timing and the duration were controlled. From the results it is observed that the optimum injection timing is at gas exchange top dead center (GTDC). The efficiency improved by about 15% with an increase in NO{sub X} emission by 3% compared to diesel. The smoke emission decreased by almost 100%. A net reduction in carbon emissions was also noticed due to the use of hydrogen. By adopting manifold injection technique the hydrogen-diesel dual fuel engine operates smoothly with a significant improvement in performance and reduction in emissions. (author)
Isolation of thermotolerant Vermamoeba vermiformis strains from water sources in Lanzarote Island, Canary Islands, Spain.

Science.gov (United States)

Reyes-Batlle, María; Wagner, Carolina; Zamora-Herrera, Jonadab; Vargas-Mesa, Alejandro; Sifaoui, Ines; González, Ana C; López-Arencibia, Atteneri; Valladares, Basilio; Martínez-Carretero, Enrique; Piñero, José E; Lorenzo-Morales, Jacob

2016-09-01

In this study, twenty water samples were collected in the island of Lanzarote, Canary Islands, Spain in order to check for the presence of V. vermiformis strains in these samples. Water samples were cultured on 2% Non-Nutrient Agar (NNA) plates covered with a thin layer of heat killed E. coli and checked daily for the presence of Vermamoeba. After a week, V. vermiformis amoebae were observed in 2 of the 20 processed samples (10%) incubated at room temperature and 37°C. Molecular characterization was carried out by amplifying the 18S rDNA gene and DNA sequencing in order to confirm the identity of the isolated amoebic strains. To the best of our knowledge, this is the first report on the presence of FLA in environmental sources in Lanzarote Island and the first report of Vermamoeba vermiformis in water sources in this island. Furthermore, the two strains isolated in this study were collected in recreational areas with close contact with humans and thus awareness should be raised.
Isolation and characterization of a bacterium which utilizes polyester polyurethane as a sole carbon and nitrogen source.

Science.gov (United States)

Nakajima-Kambe, T; Onuma, F; Kimpara, N; Nakahara, T

1995-06-01

Various soil samples were screened for the presence of microorganisms which have the ability to degrade polyurethane compounds. Two strains with good polyurethane degrading activity were isolated. The more active strain was tentatively identified as Comamonas acidovorans. This strain could utilize polyester-type polyurethanes but not the polyether-type polyurethanes as sole carbon and nitrogen sources. Adipic acid and diethylene glycol were probably the main degradation products when polyurethane was supplied as a sole carbon and nitrogen source. When ammonium nitrate was used as nitrogen source, only diethylene glycol was detected after growth on polyurethane.
Performance of the ALS injection system

International Nuclear Information System (INIS)

Kim, C.H.

1993-05-01

The authors started commissioning the Advanced Light Source (ALS) storage ring on January 11, 1993. The stored beam reached 60 mA on March 24, 1993 and 407 mA on April 9, 1993. The fast pace of storage ring commissioning can be attributed partially to the robust injection system. In this paper they describe the operating characteristics of the ALS injection system
Note: Hollow cathode lamp with integral, high optical efficiency isolation valve: A modular vacuum ultraviolet source

International Nuclear Information System (INIS)

Sloan Roberts, F.; Anderson, Scott L.

2013-01-01

The design and operating conditions of a hollow cathode discharge lamp for the generation of vacuum ultraviolet radiation, suitable for ultrahigh vacuum (UHV) application, are described in detail. The design is easily constructed, and modular, allowing it to be adapted to different experimental requirements. A thin isolation valve is built into one of the differential pumping stages, isolating the discharge section from the UHV section, both for vacuum safety and to allow lamp maintenance without venting the UHV chamber. The lamp has been used both for ultraviolet photoelectron spectroscopy of surfaces and as a “soft” photoionization source for gas-phase mass spectrometry
Note: Hollow cathode lamp with integral, high optical efficiency isolation valve: A modular vacuum ultraviolet source

Energy Technology Data Exchange (ETDEWEB)

Sloan Roberts, F.; Anderson, Scott L. [Department of Chemistry, University of Utah, 315 S. 1400 E., Salt Lake City, Utah 84112 (United States)

2013-12-15

The design and operating conditions of a hollow cathode discharge lamp for the generation of vacuum ultraviolet radiation, suitable for ultrahigh vacuum (UHV) application, are described in detail. The design is easily constructed, and modular, allowing it to be adapted to different experimental requirements. A thin isolation valve is built into one of the differential pumping stages, isolating the discharge section from the UHV section, both for vacuum safety and to allow lamp maintenance without venting the UHV chamber. The lamp has been used both for ultraviolet photoelectron spectroscopy of surfaces and as a “soft” photoionization source for gas-phase mass spectrometry.
Note: Hollow cathode lamp with integral, high optical efficiency isolation valve: a modular vacuum ultraviolet source.

Science.gov (United States)

Roberts, F Sloan; Anderson, Scott L

2013-12-01

The design and operating conditions of a hollow cathode discharge lamp for the generation of vacuum ultraviolet radiation, suitable for ultrahigh vacuum (UHV) application, are described in detail. The design is easily constructed, and modular, allowing it to be adapted to different experimental requirements. A thin isolation valve is built into one of the differential pumping stages, isolating the discharge section from the UHV section, both for vacuum safety and to allow lamp maintenance without venting the UHV chamber. The lamp has been used both for ultraviolet photoelectron spectroscopy of surfaces and as a "soft" photoionization source for gas-phase mass spectrometry.
Selective cultures for the isolation of biosurfactant producing bacteria: comparison of different combinations of environmental inocula and hydrophobic carbon sources.

Science.gov (United States)

Domingues, Patrícia M; Louvado, António; Oliveira, Vanessa; Coelho, Francisco J C R; Almeida, Adelaide; Gomes, Newton C M; Cunha, Angela

2013-01-01

The potential of estuarine microniches as reservoirs of biosurfactant-producing bacteria was evaluated by testing different combinations of inocula and hydrophobic carbon sources. Selective cultures using diesel, petroleum, or paraffin as hydrophobic carbon sources were prepared and inoculated with water from the surface microlayer, bulk sediments, and sediment of the rhizosphere of Halimione portulacoides. These inocula were compared regarding the frequency of biosurfactant-producing strains among selected isolates. The community structure of the selective cultures was profiled using denaturing gradient gel electrophoresis (DGGE) of the 16S rRNA gene fragments at the end of the incubation. The DGGE profiles corresponding to the communities established in selective cultures at the end of the incubation revealed that communities were different in terms of structural diversity. The highest diversity was observed in the selective cultures containing paraffin (H (') = 2.5). Isolates were obtained from the selective cultures (66) and tested for biosurfactant production by the atomized oil assay. Biosurfactant production was detected in 17 isolates identified as Microbacterium, Pseudomonas, Rhodococcus, and Serratia. The combination of estuarine surface microlayer (SML) water as inoculum and diesel as carbon source seems promising for the isolation of surfactant-producing bacteria. Supplemental materials are available for this article. Go to the publisher's online edition of Preparative Biochemistry and Biotechnology to view the supplemental file.
Galvanically Isolated Quasi-Z-Source DC–DC Converter With a Novel ZVS and ZCS Technique

DEFF Research Database (Denmark)

Husev, Oleksandr; Liivik, Liisa; Blaabjerg, Frede

2015-01-01

This paper focuses on the galvanically isolated quasi-Z-source dc-dc converter with a novel zero voltage and zero current switching technique. The unique feature of the impedance network lies in combining the buck-boost operation capability with the short- and open-circuit immunity of transistors......; at the same time, it can perform zero voltage and zero current switching on the primary side. The boundary conduction mode of the current in the second inductor of the quasi-Z-source network was used along with snubber capacitors in the two out of four transistors and a special control algorithm to achieve...

Genotypic and phenotypic diversity of Ralstonia pickettii and Ralstonia insidiosa isolates from clinical and environmental sources including High-purity Water.

LENUS (Irish Health Repository)

Ryan, Michael P

2011-08-30

Abstract Background Ralstonia pickettii is a nosocomial infectious agent and a significant industrial contaminant. It has been found in many different environments including clinical situations, soil and industrial High Purity Water. This study compares the phenotypic and genotypic diversity of a selection of strains of Ralstonia collected from a variety of sources. Results Ralstonia isolates (fifty-nine) from clinical, industrial and environmental origins were compared genotypically using i) Species-specific-PCR, ii) PCR and sequencing of the 16S-23S rRNA Interspatial region (ISR) iii) the fliC gene genes, iv) RAPD and BOX-PCR and v) phenotypically using biochemical testing. The species specific-PCR identified fifteen out of fifty-nine designated R. pickettii isolates as actually being the closely related species R. insidiosa. PCR-ribotyping of the 16S-23S rRNA ISR indicated few major differences between the isolates. Analysis of all isolates demonstrated different banding patterns for both the RAPD and BOX primers however these were found not to vary significantly. Conclusions R. pickettii species isolated from wide geographic and environmental sources appear to be reasonably homogenous based on genotypic and phenotypic characteristics. R. insidiosa can at present only be distinguished from R. pickettii using species specific PCR. R. pickettii and R. insidiosa isolates do not differ significantly phenotypically or genotypically based on environmental or geographical origin.
Advanced injection seeder for various applications: form LIDARs to supercontinuum sources

Science.gov (United States)

Grzes, Pawel

2017-12-01

The paper describes an injection seeder driver (prototype) for a directly modulated semiconductor laser diode. The device provides adjustable pulse duration and repetition frequency to shape an output signal. A temperature controller stabilizes a laser diode spectrum. Additionally, to avoid a back oscillation, redundant power supply holds a generation until next stages shut down. Low EMI design and ESD protection guarantee stable operation even in a noisy environment. The controller is connected to the PC via USB and parameters of the pulse are digitally controlled through a graphical interface. The injection seeder controller can be used with a majority of commercially available laser diodes. In the experimental setup a telecommunication DFB laser with 4 GHz bandwidth was used. It allows achieving subnanosecond pulses generated at the repetition rate ranging from 1 kHz to 50 MHz. The developed injection seeder controller with a proper laser diode can be used in many scientific, industrial and medical applications.
Embryonic Stem Cell-Derived Cardiomyocyte Heterogeneity and the Isolation of Immature and Committed Cells for Cardiac Remodeling and Regeneration

Directory of Open Access Journals (Sweden)

Kenneth R. Boheler

2011-01-01

Full Text Available Pluripotent stem cells represent one promising source for cell replacement therapy in heart, but differentiating embryonic stem cell-derived cardiomyocytes (ESC-CMs are highly heterogeneous and show a variety of maturation states. In this study, we employed an ESC clonal line that contains a cardiac-restricted ncx1 promoter-driven puromycin resistance cassette together with a mass culture system to isolate ESC-CMs that display traits characteristic of very immature CMs. The cells display properties of proliferation, CM-restricted markers, reduced mitochondrial mass, and hypoxia-resistance. Following transplantation into rodent hearts, bioluminescence imaging revealed that immature cells, but not more mature CMs, survived for at least one month following injection. These data and comparisons with more mature cells lead us to conclude that immature hypoxia resistant ESC-CMs can be isolated in mass in vitro and, following injection into heart, form grafts that may mediate long-term recovery of global and regional myocardial contractile function following infarction.
Optimizing the injection straight of PEP II asymmetric B Factory at SLAC

International Nuclear Information System (INIS)

Bulos, F.; Bloom, E.; Davies-White, W.; Donald, M.; Fairfield, K.; Fieguth, T.; Godfrey, G.; Holtzapple, R.; Hutton, A.; Loew, G.; Miller, R.; Sukiennicki, B.; Wen, H.; Ronan, M.

1992-04-01

The asymmetric energy PEP II B Factory proposed as an upgrade of PEP at the Stanford Linear Accelerator Center requires both a powerful low emittance source of e - e + and a very reliable and efficient injection system. The SLC linac fulfills the source requirement very well. We describe here the optimization of the optics of the injection straight to insure reliable and efficient injection
Optimizing the injection straight of PEP II asymmetric B factory at SLAC

International Nuclear Information System (INIS)

Bulos, F.; Bloom, E.; Davies-White, W.; Donald, M.; Fairfield, K.; Fieguth, T.; Godfrey, G.; Holtzapple, R.; Hutton, A.; Loew, G.; Miller, R.; Sukiennicki, B.; Wen, H.

1992-01-01

The asymmetric energy PEP II B Factory proposed as an upgrade of PEP at the Stanford Linear Accelerator Center requires both a powerful low emittance source of e - e + and a very reliable and efficient injection system. The SLC linac fulfills the source requirement very well. We describe here the optimization of the optics of the injection straight to insure reliable and efficient injection
Characterization of Escherichia coli isolates from different fecal sources by means of classification tree analysis of fatty acid methyl ester (FAME) profiles.

Science.gov (United States)

Seurinck, Sylvie; Deschepper, Ellen; Deboch, Bishaw; Verstraete, Willy; Siciliano, Steven

2006-03-01

Microbial source tracking (MST) methods need to be rapid, inexpensive and accurate. Unfortunately, many MST methods provide a wealth of information that is difficult to interpret by the regulators who use this information to make decisions. This paper describes the use of classification tree analysis to interpret the results of a MST method based on fatty acid methyl ester (FAME) profiles of Escherichia coli isolates, and to present results in a format readily interpretable by water quality managers. Raw sewage E. coli isolates and animal E. coli isolates from cow, dog, gull, and horse were isolated and their FAME profiles collected. Correct classification rates determined with leaveone-out cross-validation resulted in an overall low correct classification rate of 61%. A higher overall correct classification rate of 85% was obtained when the animal isolates were pooled together and compared to the raw sewage isolates. Bootstrap aggregation or adaptive resampling and combining of the FAME profile data increased correct classification rates substantially. Other MST methods may be better suited to differentiate between different fecal sources but classification tree analysis has enabled us to distinguish raw sewage from animal E. coli isolates, which previously had not been possible with other multivariate methods such as principal component analysis and cluster analysis.
Target and ion source developments for a helium-jet type ISOL at the Kyoto university reactor

International Nuclear Information System (INIS)

Kawase, Yoichi; Okano, Kotoyuki; Funakoshi, Yoshihiro

1985-01-01

A target system and ion sources for a He-jet type ISOL have been successfully constructed and the characteristics have been studied. The beam intensities of short-lived fission products have been much improved by increasing the He gas pressure owing to a range effect of fission products in the He gas and a short transport time effect of aerosols in a target chamber and a capillary. An oscillating electron ion source has been coupled with the He-jet system and ten kinds of elements have been ionized with efficiencies of 0.4-2.4%. A high temperature thermal ion source has been studied to ionize the alkali, alkaline-earth and rare-earth elements. The effects of the He-jet on the ion source have been discussed. (orig.)
Diversity of Clostridium perfringens isolates from various sources and prevalence of conjugative plasmids.

Science.gov (United States)

Park, Miseon; Deck, Joanna; Foley, Steven L; Nayak, Rajesh; Songer, J Glenn; Seibel, Janice R; Khan, Saeed A; Rooney, Alejandro P; Hecht, David W; Rafii, Fatemeh

2016-04-01

Clostridium perfringens is an important pathogen, causing food poisoning and other mild to severe infections in humans and animals. Some strains of C. perfringens contain conjugative plasmids, which may carry antimicrobial resistance and toxin genes. We studied genomic and plasmid diversity of 145 C. perfringens type A strains isolated from soils, foods, chickens, clinical samples, and domestic animals (porcine, bovine and canine), from different geographic areas in the United States between 1994 and 2006, using multiple-locus variable-number tandem repeat analysis (MLVA) and/or pulsed-field gel electrophoresis (PFGE). MLVA detected the genetic diversity in a majority of the isolates. PFGE, using SmaI and KspI, confirmed the MLVA results but also detected differences among the strains that could not be differentiated by MLVA. All of the PFGE profiles of the strains were different, except for a few of the epidemiologically related strains, which were identical. The PFGE profiles of strains isolated from the same domestic animal species were clustered more closely with each other than with other strains. However, a variety of C. perfringens strains with distinct genetic backgrounds were found among the clinical isolates. Variation was also observed in the size and number of plasmids in the strains. Primers for the internal fragment of a conjugative tcpH gene of C. perfringens plasmid pCPF4969 amplified identical size fragments from a majority of strains tested; and this gene hybridized to the various-sized plasmids of these strains. The sequences of the PCR-amplified tcpH genes from 12 strains showed diversity among the tcpH genes. Regardless of the sources of the isolates, the genetic diversity of C. perfringens extended to the plasmids carrying conjugative genes. Published by Elsevier Ltd.
OPTICALLY BASED CHARGE INJECTION SYSTEM FOR IONIZATION DETECTORS

International Nuclear Information System (INIS)

CHEN, H.; CITTERIO, M.; LANNI, F.; LEITE, M.A.L.; RADEKA, V.; RESCIA, S.; TAKAI, H.

2001-01-01

An optically coupled charge injection system for ionization based radiation detectors which allows a test charge to be injected without the creation of ground loops has been developed. An ionization like signal from an external source is brought into the detector through an optical fiber and injected into the electrodes by means of a photodiode. As an application example, crosstalk measurements on a liquid Argon electromagnetic calorimeter readout electrodes were performed
Closure of shallow underground injection wells

International Nuclear Information System (INIS)

Veil, J.A.; Grunewald, B.

1993-01-01

Shallow injection wells have long been used for disposing liquid wastes. Some of these wells have received hazardous or radioactive wastes. According to US Environmental Protection Agency (EPA) regulations, Class IV wells are those injection wells through which hazardous or radioactive wastes are injected into or above an underground source of drinking water (USDW). These wells must be closed. Generally Class V wells are injection wells through which fluids that do not contain hazardous or radioactive wastes are injected into or above a USDW. Class V wells that are responsible for violations of drinking water regulations or that pose a threat to human health must also be closed. Although EPA regulations require closure of certain types of shallow injection wells, they do not provide specific details on the closure process. This paper describes the regulatory background, DOE requirements, and the steps in a shallow injection well closure process: Identification of wells needing closure; monitoring and disposal of accumulated substances; filling and sealing of wells; and remediation. In addition, the paper describes a major national EPA shallow injection well enforcement initiative, including closure plan guidance for wells used to dispose of wastes from service station operations
DC injection into low voltage AC networks

Energy Technology Data Exchange (ETDEWEB)

NONE

2005-07-01

This report summarises the results of a study investigating the impact of levels of injected DC current injections on a low voltage AC distribution network systems in order to recommend acceptable limits of DC from microgeneration. Relevant literature is reviewed, and the impact of DC levels in distribution transformers, transformer modelling, and instrumental transformers are discussed. The impact of DC in residual current devices (RCD) and in domestic electricity watt hour meters is examined along with DC enhanced corrosion, corrosion failure, and the measurement of DC current injection. Sources of DC injection outlined include DC from computer power supplies, network faults, geomagnetic phenomena, lighting circuits/dimmers, and embedded generators.
Whole Genome Analysis of Injectional Anthrax Identifies Two Disease Clusters Spanning More Than 13 Years

Directory of Open Access Journals (Sweden)

Paul Keim

2015-11-01

Lay Person Interpretation: Injectional anthrax has been plaguing heroin drug users across Europe for more than 10 years. In order to better understand this outbreak, we assessed genomic relationships of all available injectional anthrax strains from four countries spanning a >12 year period. Very few differences were identified using genome-based analysis, but these differentiated the isolates into two distinct clusters. This strongly supports a hypothesis of at least two separate anthrax spore contamination events perhaps during the drug production processes. Identification of two events would not have been possible from standard epidemiological analysis. These comprehensive data will be invaluable for classifying future injectional anthrax isolates and for future geographic attribution.
Effects of temperature, pH and carbon and nitrogen sources on growth of in vitro cultures of ectomycorrhizal isolates from Pinus heldreichii forest

Energy Technology Data Exchange (ETDEWEB)

Lazarević, J.; Stojičić, D.; Keča, N.

2016-07-01

Aim of study: This study aims to provide basic information about physiological characteristics of isolates of Lactarius deliciosus (L.) Gray, Russula sanguinaria (Schumach.) Rauschert, Suillus collinitus (Fr) Kuntze, Suillus granulatus (L.) Rousell, Tricholoma batchii Gulden and Tricholoma imbricatum (Fr.) Kumm. Area of study: The isolates are obtained from Pinus heldreichii H. Christ forest in the south-eastern part of Montenegro. Material and methods: The isolates were molecularly characterised by internal transcribed spacer (ITS) sequencing and restriction fragment length polymorphism (RFLP) analysis. The effects of different temperatures (20, 22, 25°C), pHs (4, 4.5, 5.2, 5.8, 6.5, 7.5), and carbon (glucose, sucrose, dextrin, arabinose, xylose and starch) and nitrogen (NH4+, NO3- and protein) sources on their growth were examined under laboratory conditions. Main results: The studied factors established significant differences in the development of isolates. Isolates of R. sanguinaria, L. deliciosus and both Suillus, were characterised by faster growth at 22°C, while Tricholoma isolates grew faster at 25°C. S. granulatus, S. collinitus and T. imbticatum isolates grew well at lower pH values (4 - 5.2), while L. deliciosus, R. sanguinaria and T. bachii exhibited faster growth at pHs between 5.8 and 6.5. The examined isolates were able to utilize various carbohydrates as carbon sources. The biggest mycelial growth was characterised for sucrose, then glucose, dextrin, arabinose, starch and xylose. They grew on all examined nitrogen sources, while the biggest mycelia growth was achieved on ammonium, followed by nitrate and protein. Those characteristics varied amongst the species. Research highlights: Information about physiological characteristics of Tricholoma, Lactarius, Russula, as well as Suillus, are sparse. Hence, the data obtained in this study could contribute to the understanding of their function in ecosystems. (Author)
Influence of fuel injection pressures on Calophyllum inophyllum methyl ester fuelled direct injection diesel engine

International Nuclear Information System (INIS)

Nanthagopal, K.; Ashok, B.; Karuppa Raj, R. Thundil

2016-01-01

Highlights: • Effect of injection pressure of Calophyllum inophyllum biodiesel is investigated. • Engine characteristics of 100% Calophyllum inophyllum biodiesel has been performed. • Calophyllum inophyllum is a non-edible source for biodiesel production. • Increase in injection pressure of biodiesel, improves the fuel economy. • Incylinder pressure characteristics of biodiesel follows similar trend as of diesel. - Abstract: The trend of using biodiesels in compression ignition engines have been the focus in recent decades due to the promising environmental factors and depletion of fossil fuel reserves. This work presents the effect of Calophyllum inophyllum methyl ester on diesel engine performance, emission and combustion characteristics at different injection pressures. Experimental investigations with varying injection pressures of 200 bar, 220 bar and 240 bar have been carried out to analyse the parameters like brake thermal efficiency, specific fuel consumption, heat release rate and engine emissions of direct injection diesel engine fuelled with 100% biodiesel and compared with neat diesel. The experimental results revealed that brake specific fuel consumption of C. inophyllum methyl ester fuelled engine has been reduced to a great extent with higher injection pressure. Significant reduction in emissions of unburnt hydrocarbons, carbon monoxide and smoke opacity have been observed during fuel injection of biodiesel at 220 bar compared to other fuel injection pressures. However oxides of nitrogen increased with increase in injection pressures of C. inophyllum methyl ester and are always higher than that of neat diesel. In addition the combustion characteristics of biodiesel at all injection pressures followed a similar trend to that of conventional diesel.
English-language videos on YouTube as a source of information on self-administer subcutaneous anti-tumour necrosis factor agent injections.

Science.gov (United States)

Tolu, Sena; Yurdakul, Ozan Volkan; Basaran, Betul; Rezvani, Aylin

2018-05-14

The aim of this study was to evaluate the reliability, content, and quality of videos for patients available on YouTube for learning how to self-administer subcutaneous anti-tumour necrosis factor (TNF) injections. We searched for the terms Humira injection, Enbrel injection, Simponi injection, and Cimzia injection. Videos were categorised as useful information, misleading information, useful patient opinion, and misleading patient opinion by two physicians. Videos were rated for quality on a 5-point global quality scale (GQS; 1 = poor quality, 5 = excellent quality) and reliability and content using the 5-point DISCERN scale (higher scores represent greater reliability and more comprehensive videos). Of the 142 English videos, 24 (16.9%) videos were classified as useful information, 6 (4.2%) as misleading information, 47 (33.1%) as useful patient opinion, and 65 (45.8%) as misleading patient opinion. Useful videos were the most comprehensive and had the highest reliability and quality scores. The useful information and useful patient opinion videos had the highest numbers of views per day (median 8.32, IQR: 3.40-14.28 and 5.46, IQR: 3.06-14.44), as compared with 2.32, IQR: 1.63-6.26 for misleading information videos and 2.15, IQR: 1.17-7.43 for misleading patient opinion videos (p = 0.001). Almost all (91.5%) misleading videos were uploaded by individual users. There are a substantial number of English-language YouTube videos, with high quality, and rich content and reliability that can be sources of information on proper technique of anti-TNF self-injections. Physicians should direct patients to the reliable resources of information and educate them in online resource assessment, thereby improving treatment outcomes.
Progress in Titanium Metal Powder Injection Molding

Directory of Open Access Journals (Sweden)

Randall M. German

2013-08-01

Full Text Available Metal powder injection molding is a shaping technology that has achieved solid scientific underpinnings. It is from this science base that recent progress has occurred in titanium powder injection molding. Much of the progress awaited development of the required particles with specific characteristics of particle size, particle shape, and purity. The production of titanium components by injection molding is stabilized by a good understanding of how each process variable impacts density and impurity level. As summarized here, recent research has isolated the four critical success factors in titanium metal powder injection molding (Ti-MIM that must be simultaneously satisfied—density, purity, alloying, and microstructure. The critical role of density and impurities, and the inability to remove impurities with sintering, compels attention to starting Ti-MIM with high quality alloy powders. This article addresses the four critical success factors to rationalize Ti-MIM processing conditions to the requirements for demanding applications in aerospace and medical fields. Based on extensive research, a baseline process is identified and reported here with attention to linking mechanical properties to the four critical success factors.
Thyristor based short circuit current injection in isolated grids

OpenAIRE

Hoff, Bjarte; Sharma, Pawan; Østrem, Trond

2017-01-01

This paper proposes a thyristor based short circuit current injector for providing short circuit current in isolated and weak grids, where sufficient fault current to trigger circuit breakers may not be available. This will allow the use of conventional miniature circuit breakers, which requires high fault current for instantaneous tripping. The method has been validated through experiments.
The Impact of the Shallow-Trench Isolation Effect on Flicker Noise of Source Follower MOSFETs in a CMOS Image Sensor.

Science.gov (United States)

Fan, C C; Chiu, Y C; Liu, C; Lai, W W; Cheng, C H; Lin, D L; Li, G R; Lo, Y H; Chang, C W; Tsai, C C; Chang, C Y

2018-06-01

The flicker noise of source follower transistors is the dominant noise source in image sensors. This paper reports a systematic study of the shallow trench isolation effect in transistors with different sizes under high temperature conditions that correspond to the quantity of empty defect sites. The effects of shallow trench isolation sidewall defects on flicker noise characteristics are investigated. In addition, the low-frequency noise and subthreshold swing degrade simultaneously in accordance to the device gate width scaling. Both serious subthreshold leakage and considerable noise can be attributed to the high trap density near the STI edge. Consequently, we propose a coincidental relationship between the noise level and the subthreshold characteristic; its trend is identical to the experiments and simulation results.
Determination of the sources and antimicrobial resistance patterns of Salmonella isolated from the poultry industry in Southern Ethiopia.

Science.gov (United States)

Abdi, Reta Duguma; Mengstie, Fisseha; Beyi, Ashenafi Feyisa; Beyene, Takele; Waktole, Hika; Mammo, Bedasso; Ayana, Dinka; Abunna, Fufa

2017-05-18

Ethiopia set an ambitious masterplan to increase chicken meat and egg production from 2015 to 2020. Poultry breeding, multiplication and distribution centers in the country have received executive order to import, amplify and distribute commercial chickens to end users. The biosecurity and the pathogen fauna of the centers have not been evaluated as to whether the centers could implement the mission effectively without any risk. Thus, the aim of this study was to evaluate the biosecurity practices and the pathogen prevalence, risk factors and their antimicrobial resistance (AMR) using Salmonella as case study. Routine farm workers of the centers were interviewed about the different management (biosecurity) practices using a checklist. Samples (n = 270) from different sources consisting of chicken's cloacal swab (n = 244), personnel hand swab (n = 9) and bedding (n = 17) were collected from three chicken multiplication centers. Standard bacteriological methods were used for the isolation of Salmonella. Disk diffusion method was used for drug sensitivity testing. Antimicrobials were often over prescribed without confirming the cause of ill health and without susceptibility testing. The general biosecurity and flock management practices were substandard. Salmonella was isolated from 45 (16.7%) of the 270 samples. Its prevalence was significantly (pSalmonella isolation from (i) bedding, (ii) personnel hand swabs (iii) chickens, (iv) presence of more MDR isolates, (v) coupled with poor biosecurity practices in the centers could pose a risk for spreading of pathogens and drug resistant genes to the smallholder chicken producers and the public. We conclude that the poultry breeding, multiplication and distribution centers in Ethiopia, as they stand currently, seem to be a source of pathogens and AMR isolates at least for Salmonella. Therefore, strict biosecurity, personnel safety, prudent drug use, regular monitoring and traceability of Salmonella serotypes or genotypes
α-Amylase inhibitors: a review of raw material and isolated compounds from plant source.

Science.gov (United States)

Sales, Paloma Michelle; Souza, Paula Monteiro; Simeoni, Luiz Alberto; Silveira, Damaris

2012-01-01

Inhibition of α-amylase, enzyme that plays a role in digestion of starch and glycogen, is considered a strategy for the treatment of disorders in carbohydrate uptake, such as diabetes and obesity, as well as, dental caries and periodontal diseases. Plants are an important source of chemical constituents with potential for inhibition of α-amylase and can be used as therapeutic or functional food sources. A review about crude extracts and isolated compounds from plant source that have been tested for α-amylase inhibitory activity has been done. The analysis of the results shows a variety of crude extracts that present α-amylase inhibitory activity and some of them had relevant activity when compared with controls used in the studies. Amongst the phyto-constituents that have been investigated, flavonoids are one of them that demonstrated the highest inhibitory activities with the potential of inhibition related to number of hydroxyl groups in the molecule of the compound. Several phyto-constituents and plant species as α-amylase inhibitors are being reported in this article. Majority of studies have focused on the anti-amylase phenolic compounds.

Microwave Ion Source and Beam Injection for an Accelerator-driven Neutron Source

International Nuclear Information System (INIS)

Vainionpaa, J.H.; Gough, R.; Hoff, M.; Kwan, J.W.; Ludewigt, B.A.; Regis, M.J.; Wallig, J.G.; Wells, R.

2007-01-01

An over-dense microwave driven ion source capable of producing deuterium (or hydrogen) beams at 100-200 mA/cm2 and with atomic fraction >90 percent was designed and tested with an electrostatic low energy beam transport section (LEBT). This ion source was incorporated into the design of an Accelerator Driven Neutron Source (ADNS). The other key components in the ADNS include a 6 MeV RFQ accelerator, a beam bending and scanning system, and a deuterium gas target. In this design a 40 mA D+ beam is produced from a 6 mm diameter aperture using a 60 kV extraction voltage. The LEBT section consists of 5 electrodes arranged to form 2 Einzel lenses that focus the beam into the RFQ entrance. To create the ECR condition, 2 induction coils are used to create ∼ 875 Gauss on axis inside the source chamber. To prevent HV breakdown in the LEBT a magnetic field clamp is necessary to minimize the field in this region. Matching of the microwave power from the waveguide to the plasma is done by an autotuner. We observed significant improvement of the beam quality after installing a boron nitride liner inside the ion source. The measured emittance data are compared with PBGUNS simulations
Microwave Ion Source and Beam Injection for an Accelerator-Driven Neutron Source

International Nuclear Information System (INIS)

Vainionpaa, J.H.; Gough, R.; Hoff, M.; Kwan, J.W.; Ludewigt, B.A.; Regis, M.J.; Wallig, J.G.; Wells, R.

2007-01-01

An over-dense microwave driven ion source capable of producing deuterium (or hydrogen) beams at 100-200 mA/cm 2 and with atomic fraction > 90% was designed and tested with an electrostatic low energy beam transport section (LEBT). This ion source was incorporated into the design of an Accelerator Driven Neutron Source (ADNS). The other key components in the ADNS include a 6 MeV RFQ accelerator, a beam bending and scanning system, and a deuterium gas target. In this design a 40 mA D + beam is produced from a 6 mm diameter aperture using a 60 kV extraction voltage. The LEBT section consists of 5 electrodes arranged to form 2 Einzel lenses that focus the beam into the RFQ entrance. To create the ECR condition, 2 induction coils are used to create ∼ 875 Gauss on axis inside the source chamber. To prevent HV breakdown in the LEBT a magnetic field clamp is necessary to minimize the field in this region. Matching of the microwave power from the waveguide to the plasma is done by an autotuner. They observed significant improvement of the beam quality after installing a boron nitride liner inside the ion source. The measured emittance data are compared with PBGUNS simulations
ANTIMICROBIAL DRUG RESISTANCE IN STRAINS OF Escherichia coli ISOLATED FROM FOOD SOURCES

Directory of Open Access Journals (Sweden)

Mohammed Uddin Rasheed

2014-07-01

Full Text Available A variety of foods and environmental sources harbor bacteria that are resistant to one or more antimicrobial drugs used in medicine and agriculture. Antibiotic resistance in Escherichia coli is of particular concern because it is the most common Gram-negative pathogen in humans. Hence this study was conducted to determine the antibiotic sensitivity pattern of E. coli isolated from different types of food items collected randomly from twelve localities of Hyderabad, India. A total of 150 samples comprising; vegetable salad, raw egg-surface, raw chicken, unpasteurized milk, and raw meat were processed microbiologically to isolate E. coli and to study their antibiotic susceptibility pattern by the Kirby-Bauer method. The highest percentages of drug resistance in isolates of E. coli were detected from raw chicken (23.3% followed by vegetable salad (20%, raw meat (13.3%, raw egg-surface (10% and unpasteurized milk (6.7%. The overall incidence of drug resistant E. coli was 14.7%. A total of six (4% Extended Spectrum β-Lactamase (ESBL producers were detected, two each from vegetable salads and raw chicken, and one each from raw egg-surface and raw meat. Multidrug resistant strains of E. coli are a matter of concern as resistance genes are easily transferable to other strains. Pathogen cycling through food is very common and might pose a potential health risk to the consumer. Therefore, in order to avoid this, good hygienic practices are necessary in the abattoirs to prevent contamination of cattle and poultry products with intestinal content as well as forbidding the use of untreated sewage in irrigating vegetables.
Effect of Fusarium isolates and their filtrates on respiratory rate and chemical analysis of squash plants.

Science.gov (United States)

El-Shenawy, Z; Mansour, M A; El-Behrawi, S

1978-01-01

The highly pathogenic isolate stimulated the emergence of the squash seedlings first, caused, however, the highest death rate of the seedlings finally. Fusarium isolates and their culture filtrates inhibited the respiratory rate of squash plants significantly. However, F. oxysporum isolates inhibited respiration more than F. solani isolates. Seasonal changes of respiration decline show that the respiratory rate decreased with plant growth in the case of infested soil and of plants injected with culture filtrates. However, spraying Fusarium culture filtrates on the foliage gave opposite results when the plants grew older. Fusarium solani isolates decreased nitrogen content of squash stems and leaves, while F. oxysporum isolates gave reverse results. Injecting Fusarium culture filtrate into the plant decreased nitrogen content of both stems and leaves, while spraying the foliage with the filtrates increased nitrogen content more than that of the control. Phosphorus content of the stems of squash plants, sown in infested soil, was less than in the control when the plants were treated with F. solani and higher when they were treated with F. oxysporum isolates. On the other hand, the phosphorus content of squash leaves was higher than in the control. In the case of injected plants, however, the phosphorus content in stems and leaves was equal to that of the control or less, and with sprayed plants it was higher than in the control. Infesting the soil with Fusarium isolates and spraying the foliage with their culture filtrates increased potassium content of squash stems and leaves, while injecting the filtrates into the plants decreased potassium content of both stems and leaves.
The operation and monitoring of sewage disposal by stack injection

Energy Technology Data Exchange (ETDEWEB)

Jensen, D.A. [Alyeska Pipeline Service Co. (United States)

1994-12-31

A system that uses turbine exhaust to evaporate sewage, was described. The Alyeska Pipeline Service developed the system for isolated pump stations located in permafrost areas. The pumps moving the crude oil in the Trans Alaska Pipeline System (TAPS) were driven by simple cycle gas turbine engines which produce large amounts of waste heat. The waste heat was used to evaporate the sewage effluent, effectively destroying all pathogens in it. The process, known as `stack injection`, was recently upgraded to increase efficiency and safety. Stack injection was being used at five pump stations. Methods used to control operation of the stack injection system, and field data used to redesign the system were reviewed. 3 figs., 3 refs.
Aptamer-based isolation and subsequent imaging of mesenchymal stem cells in ischemic myocard by magnetic resonance imaging.

Science.gov (United States)

Schäfer, R; Wiskirchen, J; Guo, K; Neumann, B; Kehlbach, R; Pintaske, J; Voth, V; Walker, T; Scheule, A M; Greiner, T O; Hermanutz-Klein, U; Claussen, C D; Northoff, H; Ziemer, G; Wendel, H P

2007-10-01

Mesenchymal stem cells (MSC) seem to be a promising cell source for cellular cardiomyoplasty. We recently developed a new aptamer-based specific selection of MSC to provide "ready to transplant" cells directly after isolation. We evaluated MRI tracking of newly isolated and freshly transplanted MSC in the heart using one short ex vivo selection step combining specific aptamer-based isolation and labeling of the cells. Bone marrow (BM) was collected from healthy pigs. The animals were euthanized and the heart was placed in a perfusion model. During cold ischemia, immunomagnetic isolation of MSC from the BM by MSC-specific aptamers labeled with Dynabeads was performed within 2 h. For histological identification the cells were additionally stained with PKH26. Approx. 3 x 10(6) of the freshly aptamer-isolated cells were injected into the ramus interventricularis anterior (RIVA) and 5 x 10(5) cells were injected directly into myocardial tissue after damaging the respective area by freezing (cryo-scar). 3 x 10(6) of the aptamer-isolated cells were kept for further characterization (FACS and differentiation assays). 20 h after cell transplantation, MRI of the heart using a clinical 3.0 Tesla whole body scanner (Magnetom Trio, Siemens, Germany) was performed followed by histological examinations. The average yield of sorted cells from 120 ml BM was 7 x 10(6) cells. The cells were cultured and showed MSC-like properties. MRI showed reproducible artifacts within the RIVA-perfusion area and the cryo-scar with surprisingly excellent quality. The histological examination of the biopsies showed PKH26-positive cells within the areas which were positive in the MRI in contrast to the control biopsies. Immunomagnetic separation of MSC by specific aptamers linked to magnetic particles is feasible, effective and combines a specific separation and labeling technique to a "one stop shop" strategy.
Electrically Injected Twin Photon Emitting Lasers at Room Temperature

Directory of Open Access Journals (Sweden)

Claire Autebert

2016-08-01

Full Text Available On-chip generation, manipulation and detection of nonclassical states of light are some of the major issues for quantum information technologies. In this context, the maturity and versatility of semiconductor platforms are important assets towards the realization of ultra-compact devices. In this paper we present our work on the design and study of an electrically injected AlGaAs photon pair source working at room temperature. The device is characterized through its performances as a function of temperature and injected current. Finally we discuss the impact of the device’s properties on the generated quantum state. These results are very promising for the demonstration of electrically injected entangled photon sources at room temperature and let us envision the use of III-V semiconductors for a widespread diffusion of quantum communication technologies.
Effects of Lightning Injection on Power-MOSFETs

Science.gov (United States)

Celaya, Jose; Saha, Sankalita; Wysocki, Phil; Ely, Jay; Nguyen, Truong; Szatkowski, George; Koppen, Sandra; Mielnik, John; Vaughan, Roger; Goebel, Kai

2009-01-01

Lightning induced damage is one of the major concerns in aircraft health monitoring. Such short-duration high voltages can cause significant damage to electronic devices. This paper presents a study on the effects of lightning injection on power metal-oxide semiconductor field effect transistors (MOSFETs). This approach consisted of pin-injecting lightning waveforms into the gate, drain and/or source of MOSFET devices while they were in the OFF-state. Analysis of the characteristic curves of the devices showed that for certain injection modes the devices can accumulate considerable damage rendering them inoperable. Early results demonstrate that a power MOSFET, even in its off-state, can incur considerable damage due to lightning pin injection, leading to significant deviation in its behavior and performance, and to possibly early device failures.
Injecting drug use: Gendered risk.

Science.gov (United States)

Zahnow, Renee; Winstock, Adam R; Maier, Larissa J; Levy, Jay; Ferris, Jason

2018-06-01

Research demonstrates gender related differences in drug-use practices and risk behaviours. Females' structural vulnerability stemming from traditional gender roles and gender-power relations may enhance their propensity to experience injecting related risk. In this paper we explore gender differences in injection practices at the initiation event, during the first year of injecting and in the most recent 12-month period, to inform more effective harm reduction strategies. Data used in this study were drawn from the Global Drug Survey 2015. The study employs chi-square and logistic regression to assess gender differences in injection behaviours in a sample of current injectors residing in six global regions: North-West Europe; Southern Eastern Europe; North America. South America and Oceania. Females were more likely than males to report being injected by an intimate partner at initiation (OR = 4.4, 95%CI: 2.2-8.8), during the first year of injecting (OR = 4.8, 95% CI: 2.4-9.3) and in the most recent 12-month period (OR = 2.5, 95%CI: 1.0-6.2). Females reported greater difficulties accessing sterile equipment (X 2 (2,N = 453) = 8.2, p = 0.02) and were more likely to share injecting equipment than males (X 2 (1,N = 463) = 3.9, p = 0.05). Our findings highlight females' continued dependence on their intimate partner to administer the injection into the first year of their injecting career. Females remained more likely than males to rely on intimate partners for injection during the most recent 12-month period. Females report greater difficulties in sourcing sterile equipment and are more likely to share injecting equipment. We suggest that these findings reflect the broader social structure in which females are disempowered through traditional gender roles and the lack of gender appropriate harm reduction services. Copyright © 2018 Elsevier B.V. All rights reserved.
High power neutral beam injection in LHD

International Nuclear Information System (INIS)

Tsumori, K.; Takeiri, Y.; Nagaoka, K.

2005-01-01

The results of high power injection with a neutral beam injection (NBI) system for the large helical device (LHD) are reported. The system consists of three beam-lines, and two hydrogen negative ion (H - ion) sources are installed in each beam-line. In order to improve the injection power, the new beam accelerator with multi-slot grounded grid (MSGG) has been developed and applied to one of the beam-lines. Using the accelerator, the maximum powers of 5.7 MW were achieved in 2003 and 2004, and the energy of 189 keV reached at maximum. The power and energy exceeded the design values of the individual beam-line for LHD. The other beam-lines also increased their injection power up to about 4 MW, and the total injection power of 13.1 MW was achieved with three beam-lines in 2003. Although the accelerator had an advantage in high power beam injection, it involved a demerit in the beam focal condition. The disadvantage was resolved by modifying the aperture shapes of the steering grid. (author)
Molecular Characterization of Yeast Strains Isolated from Different Sources by Restriction Fragment Length Polymorphism

International Nuclear Information System (INIS)

Ali, M. S.; Latif, Z.

2016-01-01

Various molecular techniques like analysis of the amplified rDNA internal transcribed spacers (ITS), intragenic spacers and total ITS region analysis by restriction fragment length polymorphism (RFLP) has been introduced for yeast identification but there are limited databases to identify yeast species on the basis of 5.8S rDNA. In this study, twenty nine yeast strains from various sources including spoiled fruits, vegetables, foodstuffs, and concentrated juices were characterized by PCR-RFLP. PCR-RFLP has been used to characterize yeasts present in different spoiled food samples after isolation of the yeasts. By using this technique, the isolated yeast strains were characterized by direct 5.8S-ITS rDNA region amplification. RFLP analysis was applied to each of the amplification products (varied from 400bp to 800bp) detected, and the corresponding yeast identifications were made according to each specific restriction patterns obtained after treatment with two endonucleases TaqI and HaeIII which yielded a specific banding pattern for each species. For further confirmation amplified products of eleven selected isolates were sequenced and blast on NCBI. Both RFLP and sequence analyses of the strains with accession nos. KF472163, KF472164, KF472165, KF472166, KF472167, KF472168, KF472169, KF472170, KF472171, KF472172, KF472173 gave significantly similar results. The isolates were found to belong five different yeast species including; Candida spp., Pichia spp., Kluyveromyces spp., Clavispora spp. and Hanseniaspora spp. This method provides a fast, easy, reliable and authentic way for determining yeast population present in different type of samples, as compared to traditional characterization technique. (author)
Commix: Automating Evaluation and Exploitation of Command Injection Vulnerabilities in Web Applications

OpenAIRE

Stasinopoulos, Anastasios; Ntantogian, Christoforos; Xenakis, Christos

2018-01-01

Despite the prevalence and the high impact of command injection attacks, little attention has been given by the research community to this type of code injections. Although there are many software tools to detect and exploit other types of code injections, such as SQL injections or Cross Site Scripting, there is no dedicated and specialized software that detects and exploits, automatically, command injection vulnerabilities. This paper proposes an open source tool that automates the process o...
PLT neutral beam injection systems

International Nuclear Information System (INIS)

Menon, M.M.; Barber, G.C.; Blue, C.W.

1979-01-01

A brief description of the Princeton Large Torus (PLT) neutral beam injection system is given and its performance characteristics are outlined. A detailed operational procedure is included, as are some tips on troubleshooting. Proper operation of the source is shown to be a crucial factor in system performance
Deep-well injection of radioactive waste in Russia

International Nuclear Information System (INIS)

Hoek, J.

1998-01-01

In the Russian federation, deep borehole injection of liquid radioactive waste has been established practice since at least 1963. The liquid is injected into sandy or other formations with high porosity, which are isolated by water-tight layers. This technique has also been used elsewhere for toxic liquid waste and residues from mining operations. Deep-well injection of radioactive waste is not currently used in any of the European Commission (EC) countries. In this paper the results of a EC-funded study were presented. The study is entitled 'Measurements, modelling of migration and possible radiological consequences at deep well injection sites for liquid radioactive waste in Russia', COSU-CT94-0099-UK. The study was carried out jointly by AEA Technology, CAG and the Research Institute for Nuclear Reactors (NIIAR) at Dimitrovgrad. Many scientists have contributed to the results reported here. The aims of the study are: Provision of extensive information on the deep-well injection repositories and their use in the former Soviet Union; Provision of a methodology to assess safety aspects of deep-well injection of liquid radioactive waste in deep geological formations; This will allow evaluation of proposals to use deep-well injection techniques in other regions; Support for Russian regulatory bodies through evaluation of the suitability of the sites, including estimates of the maximum amount of waste that can be safely stored in them; and Provision of a methodology to assess the use of deep-well injection repositories as an alternative disposal technique for EC countries. 7 refs
Botulinum toxin injection in laryngeal dyspnea.

Science.gov (United States)

Woisard, Virginie; Liu, Xuelai; Bes, Marie Christine Arné; Simonetta-Moreau, Marion

2017-02-01

Data, regarding the use of botulinum toxin (BT-A) in laryngeal dyspnea, are scarce, coming from some cases reports in the literature, including Vocal fold paralysis, laryngeal dystonia, vocal cord dysfunction also called paradoxical motion of the vocal fold (PMVF), and post-neuroleptic laryngeal dyskinesia. There is no consensus regarding the muscles and the doses to inject. The aim of this study is to present a retrospective review of patients treated in our ENT Department by BT-A injection in this indication. This study is a retrospective study describing patients who underwent an injection of botulinum toxin for laryngeal dyspnea in the ENT Department from 2005 to 2015 years. The inclusion criteria were a dyspnea associated with a laryngeal dysfunction, confirmed by flexible fiberoptic nasopharyngolaryngoscopy. Information concerning the causes of the dyspnea, the botulinum toxin BT-A injections procedure, post-injection follow-up, and respiratory outcome were collected for all patients included. In the group of 13 patients included, the main cause identified as principal factor linked with the short breath was: a bilateral VF paralysis (Patel et al., Otolaryngol Head Neck Surg 130:686-689, 7), laryngeal dystonia (Balkissoon and Kenn, Semin Respir Crit Care Med 33:595-605, 2), Anxiety syndrome associated with unilateral vocal fold paralysis or asthma (Marcinow et al., Laryngoscope 124:1425-1430, 3), and an isolated asthma (Zwirner et al., Eur Arch Otorhinolaryngol 254:242-245, 1). Nine out of the thirteen patients were improved by the injections. A BT-A-induced stable benefit for four patients led them to stop the injections in the follow-up. Good outcome was observed in five other patients (main cause: bilateral VP paralysis), allowing a progressive lengthening of the delay between BT-A injections. Four patients did not report a positive risk/benefit ratio after BT-A injections; two of them (with bilateral VF paralysis), because of respiratory side effects and
Development of lean burn gas engines using pilot fuel for ignition source; Developpement d'un moteur a gaz avec pre-injection de carburant pour la source d'allumage

Energy Technology Data Exchange (ETDEWEB)

Sakonji, T.; Saito, H.; Sakurai, T. [Tokyo Gas Co., Ltd. (Japan); Hirashima, T.; Kanno, K. [Nissan Diesel Motor Co., Ltd. (Japan)

2000-07-01

A development was conducted to investigate the performance of an open chamber gas engine with pilot fuel for ignition source. Experiments were conducted by using a gas engine equipped with a common-rail injection system. Main gas fuel is supplied to the engine cylinder, and then a small quantity of diesel fuel (approximately 1 % of total fuel energy input) was injected into the main chamber for ignition. The single cylinder prototype gas engine has demonstrated superior performance, such as, a shaft-end thermal efficiency of 36.7% with NO{sub x} level of 0.4 g/kW-h, which equals those of conventional spark ignited pre-chamber lean burn gas engines. For the next step, the multi-cylinder gas engine has been developed. That has 138 mm bore, 142 mm stroke, V8 configuration and 229 kW engine output 1500 rpm. This engine can also run with only diesel fuel for Standby-Power-Concurrent Co-generation. (authors)
Hydrogen ion species analysis and related neutral beam injection power assessment in the Heliotron E neutral beam injection system

International Nuclear Information System (INIS)

Sano, Fumimichi; Obiki, Tokuhiro; Sasaki, Akihiko; Iiyoshi, Atsuo; Uo, Koji

1982-01-01

The hydrogen ion species in a Heliotron E neutral beam injection system of maximum electric power 6.3 MW were analyzed in order to assess the neutral beam power injected into the torus. The masimum p roton ratio of the cylindrical bucket type ion source used was observed to be more than 90 percent assuming that the angular divergences for the respective species in the beam are the same. The experimental data are compared with calculations using a particle balance model. The analysis indicates that the net injection power reaches nearly 2.7 MW at the optimal conditions of the system considering the geometrical limitation of the neutral beam path. (author)
Determining How Magnetic Helicity Injection Really Works

International Nuclear Information System (INIS)

Paul M Bellan

2001-01-01

OAK-B135 The goal of the Caltech program is to determine how helicity injection works by investigating the actual dynamics and topological evolution associated with magnetic relaxation. A new coaxial helicity injection source has been constructed and brought into operation. The key feature of this source is that it has maximum geometric simplicity. Besides being important for fusion research, this work also has astrophysical implications. Photos obtained using high-speed cameras show a clear sequence of events in the formation process. In particular, they show initial merging/reconnection processes, jet-like expansion, kinking, and separation of the plasma from the source. Various diagnostics have been developed, including laser induced fluorescence and soft x-ray detection using high speed diodes. Gas valves have been improved and a patent disclosure relating to puffed gas valves has been filed. Presentations on this work have been given in the form of invited talks at several university physics departments that were previously unfamiliar with laboratory plasma experiments
Virulence Genes among Enterococcus faecalis and Enterococcus faecium Isolated from Coastal Beaches and Human and Nonhuman Sources in Southern California and Puerto Rico

Directory of Open Access Journals (Sweden)

Donna M. Ferguson

2016-01-01

Full Text Available Most Enterococcus faecalis and E. faecium are harmless to humans; however, strains harboring virulence genes, including esp, gelE, cylA, asa1, and hyl, have been associated with human infections. E. faecalis and E. faecium are present in beach waters worldwide, yet little is known about their virulence potential. Here, multiplex PCR was used to compare the distribution of virulence genes among E. faecalis and E. faecium isolated from beaches in Southern California and Puerto Rico to isolates from potential sources including humans, animals, birds, and plants. All five virulence genes were found in E. faecalis and E. faecium from beach water, mostly among E. faecalis. gelE was the most common among isolates from all source types. There was a lower incidence of asa1, esp, cylA, and hyl genes among isolates from beach water, sewage, septage, urban runoff, sea wrack, and eelgrass as compared to human isolates, indicating that virulent strains of E. faecalis and E. faecium may not be widely disseminated at beaches. A higher frequency of asa1 and esp among E. faecalis from dogs and of asa1 among birds (mostly seagull suggests that further studies on the distribution and virulence potential of strains carrying these genes may be warranted.
Fault Diagnosis Of A Water For Injection System Using Enhanced Structural Isolation

DEFF Research Database (Denmark)

Laursen, Morten; Blanke, Mogens; Düstegör, Dilek

2008-01-01

A water for injection system supplies chilled sterile water as solvent to pharmaceutical products. There are ultimate requirements to the quality of the sterile water, and the consequence of a fault in temperature or in flow control within the process may cause loss of one or more batches...

Viscous hydrophilic injection matrices for serial crystallography

Directory of Open Access Journals (Sweden)

Gabriela Kovácsová

2017-07-01

Full Text Available Serial (femtosecond crystallography at synchrotron and X-ray free-electron laser (XFEL sources distributes the absorbed radiation dose over all crystals used for data collection and therefore allows measurement of radiation damage prone systems, including the use of microcrystals for room-temperature measurements. Serial crystallography relies on fast and efficient exchange of crystals upon X-ray exposure, which can be achieved using a variety of methods, including various injection techniques. The latter vary significantly in their flow rates – gas dynamic virtual nozzle based injectors provide very thin fast-flowing jets, whereas high-viscosity extrusion injectors produce much thicker streams with flow rates two to three orders of magnitude lower. High-viscosity extrusion results in much lower sample consumption, as its sample delivery speed is commensurate both with typical XFEL repetition rates and with data acquisition rates at synchrotron sources. An obvious viscous injection medium is lipidic cubic phase (LCP as it is used for in meso membrane protein crystallization. However, LCP has limited compatibility with many crystallization conditions. While a few other viscous media have been described in the literature, there is an ongoing need to identify additional injection media for crystal embedding. Critical attributes are reliable injection properties and a broad chemical compatibility to accommodate samples as heterogeneous and sensitive as protein crystals. Here, the use of two novel hydrogels as viscous injection matrices is described, namely sodium carboxymethyl cellulose and the thermo-reversible block polymer Pluronic F-127. Both are compatible with various crystallization conditions and yield acceptable X-ray background. The stability and velocity of the extruded stream were also analysed and the dependence of the stream velocity on the flow rate was measured. In contrast with previously characterized injection media, both new
Design of power supply system for the prototype RF-driven negative ion source for neutral beam injection application

Energy Technology Data Exchange (ETDEWEB)

Jiang, Caichao; Hu, Chundong [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Graduate school, University of Science and Technology of China, Hefei 230026 (China); Wei, Jianglong, E-mail: jlwei@ipp.ac.cn [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Xie, Yahong; Xu, Yongjian; Liang, Lizhen; Chen, Shiyong; Liu, Sheng; Liu, Zhimin; Xie, Yuanlai [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China)

2017-04-15

Highlights: • A supporting power supply system was designed in details for a RF-driven prototype negative ion source at ASIPP. • The RF power supply for plasma generation adopts an all-solid-state power supply structure. • The extraction grid power supply adopts the pulse step modulator (PSM) technology. - Abstract: In order to study the generation and extraction of negative ions for neutral beam injection application, a prototype RF-driven negative ion source and the corresponding test bed are under construction at Institute of Plasma Physics, Chinese Academy of Sciences (ASIPP). The target of the negative ion source is extracting a negation ion beam of 350 A/m{sup 2} for 3600 s plasma duration and 100 s beam duration. According to the required parameters of test bed, the design of power supply system is put forward for earlier study. In this paper, the performance requirements and design schemes of RF power supply for plasma generation, impedance matching network, bias voltage power supply, and extraction voltage power supply for negative beam extraction are introduced in details. The schemes provide a reference for the construction of power supply system and lay a foundation for the next phase of experimental operation.
A simple scheme for injection and extraction in compact rings

International Nuclear Information System (INIS)

Xu, H. S.; Huang, W. H.; Tang, C. X.

2014-01-01

There has been great interest in building compact synchrotrons for various applications, for example, inverse Compton scattering X-ray sources. However, the beam injection and extraction in compact rings require careful design for the lack of space. In this paper, we propose a simple combined injection-extraction scheme exploiting the fringe field of existing dipole magnets instead of additional septum magnets. This scheme is illustrated by using the 4.8 m ring proposed for Tsinghua Thomson scattering X-ray source as an example. Particle tracking is applied to demonstrate the validity of this scheme
Syringe vending machines for injection drug users: an experiment in Marseille, France.

Science.gov (United States)

Obadia, Y; Feroni, I; Perrin, V; Vlahov, D; Moatti, J P

1999-01-01

OBJECTIVES: This study evaluated the usefulness of vending machines in providing injection drug users with access to sterile syringes in Marseille, France. METHODS: Self-administered questionnaires were offered to 485 injection drug users obtaining syringes from 32 pharmacies, 4 needle exchange programs, and 3 vending machines. RESULTS: Of the 343 respondents (response rate = 70.7%), 21.3% used the vending machines as their primary source of syringes. Primary users of vending machines were more likely than primary users of other sources to be younger than 30 years, to report no history of drug maintenance treatment, and to report no sharing of needles or injection paraphernalia. CONCLUSIONS: Vending machines may be an appropriate strategy for providing access to syringes for younger injection drug users, who have typically avoided needle exchange programs and pharmacies. PMID:10589315
First neutral beam injection experiments on KSTAR tokamaka)

Science.gov (United States)

Jeong, S. H.; Chang, D. H.; Kim, T. S.; In, S. R.; Lee, K. W.; Jin, J. T.; Chang, D. S.; Oh, B. H.; Bae, Y. S.; Kim, J. S.; Park, H. T.; Watanabe, K.; Inoue, T.; Kashiwagi, M.; Dairaku, M.; Tobari, H.; Hanada, M.

2012-02-01

The first neutral beam (NB) injection system of the Korea Superconducting Tokamak Advanced Research (KSTAR) tokamak was partially completed in 2010 with only 1/3 of its full design capability, and NB heating experiments were carried out during the 2010 KSTAR operation campaign. The ion source is composed of a JAEA bucket plasma generator and a KAERI large multi-aperture accelerator assembly, which is designed to deliver a 1.5 MW, NB power of deuterium at 95 keV. Before the beam injection experiments, discharge, and beam extraction characteristics of the ion source were investigated. The ion source has good beam optics in a broad range of beam perveance. The optimum perveance is 1.1-1.3 μP, and the minimum beam divergence angle measured by the Doppler shift spectroscopy is 0.8°. The ion species ratio is D+:D2+:D3+ = 75:20:5 at beam current density of 85 mA/cm2. The arc efficiency is more than 1.0 A/kW. In the 2010 KSTAR campaign, a deuterium NB power of 0.7-1.5 MW was successfully injected into the KSTAR plasma with a beam energy of 70-90 keV. L-H transitions were observed within a wide range of beam powers relative to a threshold value. The edge pedestal formation in the Ti and Te profiles was verified through CES and electron cyclotron emission diagnostics. In every deuterium NB injection, a burst of D-D neutrons was recorded, and increases in the ion temperature and plasma stored energy were found.
Extraordinary mullet growth through direct injection of foreign DNA ...

African Journals Online (AJOL)

The present study aims to produce a genetically modified grey mullet, Mugil cephalus, with accelerated growth through direct injection of foreign DNA isolated from the liver of shark (Squalus acanthias L.) or African catfish (Clarias gariepinus) into muscles of fingerlings fish at the dose of 40 μg/fish. The results show a ...
Properties of humic substances isolated from different natural sources

Directory of Open Access Journals (Sweden)

G Dolmaa

2014-10-01

Full Text Available The purpose of study was to determine properties of humic substances by combination of modern and traditional methods. Humic substances isolated from three different sources from Mongolia such as peloid from Lake Gurban nuur, coal from Baganuur deposit and oil shale from Shine khudag deposit. On the basis of determination H/C and O/C atomic ratios in humic substances by elemental analysis, confirmed existing of aromatic structures in the molecules and oxidized functional groups. Have been studied the structure of humic substances by spectral method. For example infrared spectrums showed that humic substances are characterizing with poly-structural components, with different quantity in the samples. Light adsorption of samples in the UV-Vis region, a decrease on the absorption intensity with an increase of the wave length was observed (Fig. 2. The high ratio Н/С, attributed to stretching of C=C bond of aromatic rings in IR spectrums, the high content of functional groups, lower extinction coefficients, confirmed that aromatic fragments to prevail than aliphatic chain fragments in structure of all studied HS. DOI: http://dx.doi.org/10.5564/mjc.v14i0.199 Mongolian Journal of Chemistry 14 (40, 2013, p51-56
Isolation colling device for reactor

International Nuclear Information System (INIS)

Ikehara, Morihiko; Arai, Shigeki.

1982-01-01

Purpose: To prevent undesired operation of an emergency core cooling system due to excess lowering of water level in a reactor. Constitution: In an emergency facility adapted to drive a turbine, upon reactor isolation, with the excess steams of the reactor to operate a pump and thereby inject cooling water to the reactor, a water level detector is provided and connected to a pump exhaust valve control circuit, a turbine inlet valve control circuit and a by-pass valve control circuit. Valve ON-OFF is automatically controlled depending on the water level to thereby render the level constant. A by-pass pipe is branched from a pump exhaust pipe and connected to a condensate storage tank. When the water level rises due to water injection, the injecting water is returned to circulate by way of the by-pass pipe to the condensate storage tank under the ON-OFF for each of the valves while the turbine being kept to drive. Then, if the water level is lowered, water injection is started again by the ON-OFF for each of the valves. (Ikeda, J.)
Problems of heat sources modeling on stage of isolated power systems expansion planning

International Nuclear Information System (INIS)

Malenkov, A.V.; Reshetnikova, L.N.; Sergeev, Yu.A.

1998-01-01

It is necessary to use computer codes for evaluation of possible applications and role of nuclear district heating plants in the local self-balancing power and heating systems, which are to be located in the remote isolated and hardly accessible regions in the Far North of Russia. Key factors in determining system configurations and its performances are: (1) interdependency of electricity, heat and fuel supply; (2) long distance between energy consumer centres (from several tens up to some hundred kilometers); and (3) difficulty in export and import of the electricity, especially the fuel in and from neighbouring and remote regions. The problem to challenge is to work out an optimum expansion plan of the local electricity and heat supply system. The ENPEP (ENergy and Power Evaluation Program) software package, which was developed by IAEA together with the USA Argonne National Laboratory, was chosen for this purpose. The Chaun-Bilibino power system (CBPS), an isolated power system in far North-East region of Russia, was selected as the first case of the ENPEP study. ENPEP allows a complex approach in the system expansion optimization planning in the time frame of planning period of up to 30 years. The key ENPEP module, ELECTRIC, considers electricity as the only product. The cogeneration part (heat production) must be considered outside the ELECTRIC model and then the results to be transfer ed to ELECTRIC. The ENPEP study on the Chaun-Bilibino isolated power system has shown that the modelling of the heat supply sources in ENPEP is not a trivial problem. It is very important and difficult to correctly represent specific features of cogeneration process at the same time. (author)
Temperature stabilization of injection lasers

International Nuclear Information System (INIS)

Albanese, A.

1987-01-01

Apparatus which stabilizes the temperature, and thereby the output wavelength, of an injection laser. Means monitor the laser terminal voltage across a laser and derive a voltage therefrom which is proportional to the junction voltage of the laser. Means compares the voltage to a reference value from source and a temperature controller adjusts the laser temperature in response to the results of the comparison. Further embodiments of the present invention vary the output wavelength of the laser by varying the reference value from source against which the laser junction voltage is compared. (author)
Drug injecting and HIV risk among injecting drug users in Hai Phong, Vietnam: a qualitative analysis.

Science.gov (United States)

Ahmed, Tanvir; Long, Thanh Nguyen; Huong, Phan Thi; Stewart, Donald Edwin

2015-01-29

Hai Phong, located in northern Vietnam, has become a high HIV prevalence province among Injecting Drug Users (IDUs) since the infection shifted from the southern to the northern region of the country. Previous research indicates high levels of drug and sex related risk behaviour especially among younger IDUs. Our recent qualitative research provides a deeper understanding of HIV risk behaviour and highlights views and experiences of IDUs relating to drug injecting and sharing practices. Fifteen IDUs participated in semi-structured interviews conducted in September-October, 2012. Eligible participants were selected from those recruited in a larger scale behavioural research project and identified through screening questions. Interviews were conducted by two local interviewers in Vietnamese and were audiotaped. Ethical procedures, including informed consent and participants' understanding of their right to skip and withdraw, were applied. Transcripts were translated and double checked. The data were categorised and coded according to themes. Thematic analysis was conducted and a qualitative data analysis thematic framework was used. Qualitative analysis highlighted situational circumstances associated with HIV risks among IDUs in Hai Phong and revealed three primary themes: (i) places for injecting, (ii) injecting drugs in small groups, and (iii) sharing practices. Our results showed that shared use of jointly purchased drugs and group injecting were widespread among IDUs without adequate recognition of these as HIV risk behaviours. Frequent police raids generated a constant fear of arrest. As a consequence, the majority preferred either rail lines or isolated public places for injection, while some injected in their own or a friend's home. Price, a heroin crisis, and strong group norms encouraged collective preparation and group injecting. Risk practices were enhanced by a number of factors: the difficulty in getting new syringes, quick withdrawal management
Noise cancellation in magnetoencephalography and electroencephalography with isolated reference sensors

Science.gov (United States)

Kraus, Jr., Robert H.; Espy, Michelle A.; Matlachov, Andrei; Volegov, Petr

2010-06-01

An apparatus measures electromagnetic signals from a weak signal source. A plurality of primary sensors is placed in functional proximity to the weak signal source with an electromagnetic field isolation surface arranged adjacent the primary sensors and between the weak signal source and sources of ambient noise. A plurality of reference sensors is placed adjacent the electromagnetic field isolation surface and arranged between the electromagnetic isolation surface and sources of ambient noise.
Local myogenic pulp-derived cell injection enhances craniofacial muscle regeneration in vivo.

Science.gov (United States)

Jung, J E; Song, M J; Shin, S; Choi, Y J; Kim, K H; Chung, C J

2017-02-01

To enhance myogenic differentiation in pulp cells isolated from extracted premolars by epigenetic modification using a DNA demethylation agent, 5-aza-2'-deoxycytidine (5-Aza), and to evaluate the potent stimulatory effect of 5-Aza-treated pulp cell injection for craniofacial muscle regeneration in vivo. Pulp cells were isolated from premolars extracted for orthodontic purposes from four adults (age range, 18-22.1 years). Levels of myogenic differentiation and functional contraction response in vitro were compared between pulp cells with or without pre-treatment of 5-Aza. Changes in muscle regeneration in response to green fluorescent protein (GFP)-labelled myogenic pulp cell injection in vivo were evaluated using a cardiotoxin (CTX)-induced muscle injury model of the gastrocnemius as well as the masseter muscle in mice. Pre-treatment of 5-Aza in pulp cells stimulated myotube formation, myogenic differentiation in terms of desmin and myogenin expression, and the level of collagen gel contraction. The local injection of 5-Aza pre-treated myogenic pulp cells was engrafted into the host tissue and indicated signs of enhanced muscle regeneration in both the gastrocnemius and the masseter muscles. The epigenetic modification of pulp cells from extracted premolars and the local injection of myogenic pulp cells may stimulate craniofacial muscles regeneration in vivo. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Near-Source Error Sensor Strategies for Active Vibration Isolation of Machines

NARCIS (Netherlands)

Beijers, C.A.J.; Basten, T.G.H.; de Boer, Andries; van den Brink, D.R.; Verheij, J.W.; Sas, P; de Munck, M.

2004-01-01

Due to lightweight construction of vehicles and ships, the reduction of structure borne interior noise problems with passive isolation of engine vibrations might be not sufficient. To improve the isolation, a combination of passive and active isolation techniques can be used (so-called hybrid
GANIL Workshop on Ion Sources; Journees Sources d'Ions

Energy Technology Data Exchange (ETDEWEB)

Leroy, Renan [Grand Accelerateur National d' Ions Lourds (GANIL), 14 - Caen (France)

1999-07-01

The proceedings of the GANIL Workshop on Ion Sources held at GANIL - Caen on 18-19 March 1999 contains 13 papers aiming at improving the old source operation and developing new types of sources for nuclear research and studies of ion physics. A number of reports are devoted to applications like surface treatment, ion implantation or fusion injection. The 1+{yields}n+ transformation, charged particle transport in ECR sources, addition of cesium and xenon in negative ion sources and other basic issues in ion sources are also addressed.
Use of multiple-locus variable-number of tandem repeats analysis (MLVA) to investigate genetic diversity of Salmonella enterica subsp. enterica serovar Typhimurium isolates from human, food, and veterinary sources

DEFF Research Database (Denmark)

Mateva, Gergana; Pedersen, Karl; Sørensen, Gitte

2017-01-01

-locus variable-number of tandem repeats analysis (MLVA) and compared results with antimicrobial resistance (AMR) determinations for 100 S. Typhimurium strains isolated in Bulgaria during 2008-2012 (50 veterinary/food and 50 human isolates). Results showed that isolates were divided into 80 and 34 groups using......). No clustering of isolates related to susceptibility/resistance to antimicrobials, source of isolation, or year of isolation was observed. Some MLVA types were found in both human and veterinary/food isolates, indicating a possible route of transmission. A majority (83%) of the isolates were found...
Outcome analysis of two different injection solutions for epidural injection in radicular lumbar backache syndromes

International Nuclear Information System (INIS)

Saqib, M.; Mukhtar, M.; Bhatti, S.N; Afridi, E.A.K.; Khan, R.

2017-01-01

Background: Backache is a significant source of disability and suffering in our society. The treatment modalities need continued enhancement in order to achieve the desired goals of lowering morbidity and financial losses while improving the response of the patient. Methods: This prospective comparative study was conducted at the department of Orthopaedics and Spine Surgery, Khyber Teaching Hospital Peshawar from July 2013 to June 2015. Two interventional groups were designated; Group 1 was comprised of 54 patients who were injected with epidural bupivacaine plus methylprednisolone while Group 2 included 55 patients who were injected with bupivacaine only. Outcome was assessed using the visual analogue scale and Oswestry disability index (ODI). Results: Fifty-five female and 54 male patients with mean age 49.37 years+-10.46 SD, Mean symptoms duration was 15.01 months+-9.32 SD. Common presenting symptoms were backache (77.1 percent), lower limbs pain (66.1 percent), dermatomal paresthesias (54.1 percent) and neurogenic claudication in 57.8 percent patients. The mean visual analogue score (VAS) after injection was 3.18+-1.29 while mean ODI after injection was 23.615. There was a statistically significant reduction in VAS scores (2-sided p=0.003, OR =4.03, 95 percent CI: 1.535-10.60) following the injection. Conclusion: An epidural spinal injection is a viable option for achieving relief of pain and improves functioning in individuals with radicular backache. However, further research is advised in order to clarify the role of ESI for long-term relief. (author)
Distribution of 15N-labeled urea injected into field-grown corn plants

International Nuclear Information System (INIS)

Zhou, X.; Madrmootoo, C.A.; Mackenzie, A.F.; Smith, D.L.

1998-01-01

Nitrogen (N) assimilate supply to developing corn (Zea mays L.) ears plays a critical role in grain dry weight accumulation. The use of stem-perfused/injected 15N labeled compounds to determine the effects of an artificial N source on the subsequent distribution of injected N and grain weight of field-grown corn plants has not been reported previously. Our objective was to assess the distribution of N added via an artificial source. Three soil N fertilizer levels (0, 180, and 270 kg N ha-1) and three N solutions (distilled water control and 15N enriched urea at 15 and 30 mM N) were arranged in a split-plot design. Three N concentrations were injected using a pressurized stem injection technique. The injection started fifteen days after silking and continued until immediately prior to plant physiological maturity. The average uptake volume was 256 mL over the 30-day injection period. The N supplied via injection represented 1.5 to 3% of the total plant N. Neither soil applied N fertilizer nor injected N altered dry matter distribution among plant tissues. As the concentration of N in the injected solutions increased, N concentrations increased in the grain and upper stalks, and % 15N atom excess in ear+1 leaves and leaves increased. The relative degree of 15N enrichment for each of the tissues measured was injected internode grain upper stalks leaves lower stalks cob husk ear + 1 leaf ear leaf. This study indicated that the exogenous N supplied via stem-injection, was incorporated into all the measured plant parts, although not uniformly. The distribution of the injected 15N was affected both by the proximity of sinks to the point of injection and the strength of the various sinks
First neutral beam injection experiments on KSTAR tokamak.

Science.gov (United States)

Jeong, S H; Chang, D H; Kim, T S; In, S R; Lee, K W; Jin, J T; Chang, D S; Oh, B H; Bae, Y S; Kim, J S; Park, H T; Watanabe, K; Inoue, T; Kashiwagi, M; Dairaku, M; Tobari, H; Hanada, M

2012-02-01

The first neutral beam (NB) injection system of the Korea Superconducting Tokamak Advanced Research (KSTAR) tokamak was partially completed in 2010 with only 1∕3 of its full design capability, and NB heating experiments were carried out during the 2010 KSTAR operation campaign. The ion source is composed of a JAEA bucket plasma generator and a KAERI large multi-aperture accelerator assembly, which is designed to deliver a 1.5 MW, NB power of deuterium at 95 keV. Before the beam injection experiments, discharge, and beam extraction characteristics of the ion source were investigated. The ion source has good beam optics in a broad range of beam perveance. The optimum perveance is 1.1-1.3 μP, and the minimum beam divergence angle measured by the Doppler shift spectroscopy is 0.8°. The ion species ratio is D(+):D(2)(+):D(3)(+) = 75:20:5 at beam current density of 85 mA/cm(2). The arc efficiency is more than 1.0 A∕kW. In the 2010 KSTAR campaign, a deuterium NB power of 0.7-1.5 MW was successfully injected into the KSTAR plasma with a beam energy of 70-90 keV. L-H transitions were observed within a wide range of beam powers relative to a threshold value. The edge pedestal formation in the T(i) and T(e) profiles was verified through CES and electron cyclotron emission diagnostics. In every deuterium NB injection, a burst of D-D neutrons was recorded, and increases in the ion temperature and plasma stored energy were found.
Target injection and engagement for neutron generation at 1 Hz

International Nuclear Information System (INIS)

Komeda, Osamu; Mori, Yoshitaka; Nishimura, Yasuhiko

2013-01-01

Target injection is a key technology to realizing inertial fusion energy. Here we present the first demonstration of target injection and neutron generation. We injected more than 600 spherical deuterated polystyrene (C 8 D 8 ) bead targets during 10 minutes at 1 Hz. After the targets fell for a distance of 18 cm, we applied the synchronized laser-diode-pumped ultra-intense laser HAMA and successfully generated neutrons repeatedly. The result is a step toward fusion power and also suggests possible industrial neutron sources. (author)

Safe injection procedures, injection practices, and needlestick ...

African Journals Online (AJOL)

Results: Safe injection procedures regarding final waste disposal were sufficiently adopted, while measures regarding disposable injection equipment, waste containers, hand hygiene, as well as injection practices were inadequately carried out. Lack of job aid posters that promote safe injection and safe disposal of ...
Diesel injector dynamic modelling and estimation of injection parameters from impact response part 2: prediction of injection parameters from monitored vibration

OpenAIRE

Gu, Fengshou; Ball, Andrew; Rao, K K

1996-01-01

Part 2 of this paper presents the experimental and analytical procedures used in the estimation of injection parameters from monitored vibration. The mechanical and flow‐induced sources of vibration in a fuel injector are detailed and the features of the resulting vibration response of the injector body are discussed. Experimental engine test and data acquisition procedures are described, and the use of an out‐of‐the‐engine test facility to confirm injection dependent vibration response is ou...
Aptamer-based isolation and subsequent imaging of mesenchymal stem cells in ischemic myocard by magnetic resonance imaging

Energy Technology Data Exchange (ETDEWEB)

Schaefer, R.; Hermanutz-Klein, U.; Northoff, H. [Universitaetsklinikum Tuebingen (Germany). Inst. fuer Klinische und Experimentelle Transfusionsmedizin; Wiskirchen, J.; Kehlbach, R.; Pintaske, J. [Universitaetsklinikum Tuebingen (Germany). Abt. fuer Radiologische Diagnostik; Guo, K.; Neumann, B.; Voth, V.; Walker, T.; Scheule, A.M.; Greiner, T.O.; Ziemer, G.; Wendel, H.P. [Universitaetsklinikum Tuebingen (Germany). Abt. fuer Thorax-, Herz- und Gefaesschirurgie; Claussen, C.D. [Universitaetsklinikum Tuebingen (Germany). Radiologische Universitaetsklinik

2007-10-15

Purpose: Mesenchymal stem cells (MSC) seem to be a promising cell source for cellular cardiomyoplasty. We recently developed a new aptamer-based specific selection of MSC to provide ''ready to transplant'' cells directly after isolation. We evaluated MRI tracking of newly isolated and freshly transplanted MSC in the heart using one short ex vivo selection step combining specific aptamer-based isolation and labeling of the cells. Materials and Methods: Bone marrow (BM) was collected from healthy pigs. The animals were euthanized and the heart was placed in a perfusion model. During cold ischemia, immunomagnetic isolation of MSC from the BM by MSC-specific aptamers labeled with Dynabeads {sup registered} was performed within 2 h. For histological identification the cells were additionally stained with PKH26. Approx. 3 x 10{sup 6} of the freshly aptamer-isolated cells were injected into the ramus interventricularis anterior (RIVA) and 5 x 10{sup 5} cells were injected directly into myocardial tissue after damaging the respective area by freezing (cryo-scar). 3 x 10{sup 6} of the aptamer-isolated cells were kept for further characterization (FACS and differentiation assays). 20 h after cell transplantation, MRI of the heart using a clinical 3.0 Tesla whole body scanner (Magnetom Trio, Siemens, Germany) was performed followed by histological examinations. Results: The average yield of sorted cells from 120 ml BM was 7 x 10{sup 6} cells. The cells were cultured and showed MSC-like properties. MRI showed reproducible artifacts within the RIVA-perfusion area and the cryo-scar with surprisingly excellent quality. The histological examination of the biopsies showed PKH26-positive cells within the areas which were positive in the MRI in contrast to the control biopsies. Conclusion: Immunomagnetic separation of MSC by specific aptamers linked to magnetic particles is feasible, effective and combines a specific separation and labeling technique to a &apos
Electrically Injected UV-Visible Nanowire Lasers

Energy Technology Data Exchange (ETDEWEB)

Wang, George T.; Li, Changyi; Li, Qiming; Liu, Sheng; Wright, Jeremy Benjamin; Brener, Igal; Luk, Ting -Shan; Chow, Weng W.; Leung, Benjamin; Figiel, Jeffrey J.; Koleske, Daniel D.; Lu, Tzu-Ming

2015-09-01

There is strong interest in minimizing the volume of lasers to enable ultracompact, low-power, coherent light sources. Nanowires represent an ideal candidate for such nanolasers as stand-alone optical cavities and gain media, and optically pumped nanowire lasing has been demonstrated in several semiconductor systems. Electrically injected nanowire lasers are needed to realize actual working devices but have been elusive due to limitations of current methods to address the requirement for nanowire device heterostructures with high material quality, controlled doping and geometry, low optical loss, and efficient carrier injection. In this project we proposed to demonstrate electrically injected single nanowire lasers emitting in the important UV to visible wavelengths. Our approach to simultaneously address these challenges is based on high quality III-nitride nanowire device heterostructures with precisely controlled geometries and strong gain and mode confinement to minimize lasing thresholds, enabled by a unique top-down nanowire fabrication technique.
Axial injection in Orsay superconducting cyclotron

International Nuclear Information System (INIS)

Depauw, J.; Kugler, M.F.; Legoff, A.; Potier, J.C.; Richomme, A.; Skowron, R.; Mandrillon, P.; Schapira, J.P.

1983-01-01

The compact superconducting cyclotron currently planned at IPN at Orsay is designed for light ion acceleration together with heavy ion acceleration. From the beginning, for this reason, a central geometry able to receive an inflector (to 90deg C) allowing the axial injection of low energy ion beams given by an outer source. The present study is aimed at showing the technical feasibility of theoretical results obtained on axial injection. First experimental study has been made of spatial repartition in three dimensions of electric potential developed by a central geometry of 3 electrodes. Then, the electric study of an electrostatic mirror has been made [fr
Injection locking of optomechanical oscillators via acoustic waves.

Science.gov (United States)

Huang, Ke; Hossein-Zadeh, Mani

2018-04-02

Injection locking is an effective technique for synchronization of oscillator networks and controlling the phase and frequency of individual oscillators. As such, exploring new mechanisms for injection locking of emerging oscillators is important for their usage in various systems. Here, we present the first demonstration of injection locking of a radiation pressure driven optomechanical oscillator (OMO) via acoustic waves. As opposed to previously reported techniques (based on pump modulation or direct application of a modulated electrostatic force), injection locking of OMO via acoustic waves does not require optical power modulation or physical contact with the OMO and it can be easily implemented on various platforms to lock different types of OMOs independent of their size and structure. Using this approach we have locked the phase and frequency of two distinct modes of a microtoroidal silica OMO to a piezoelectric transducer (PZT). We have characterized the behavior of the injection locked OMO with three acoustic excitation configurations and showed that even without proper acoustic impedance, matching the OMO can be locked to the PZT and tuned over 17 kHz with only -30 dBm of RF power fed to the PZT. The high efficiency, simplicity, and scalability of the proposed approach paves the road toward a new class of photonic systems that rely on synchronization of several OMOs to a single or multiple RF oscillators with applications in optical communication, metrology, and sensing. Beyond its practical applications, injection locking via acoustic waves can be used in fundamental studies in quantum optomechanics where thermal and optical isolation of the OMO are critical.
Low energy, high power injection in JT-60 NBI

International Nuclear Information System (INIS)

Mizuno, Makoto; Dairaku, Masayuki; Horiike, Hiroshi

1988-05-01

JT-60 neutral beam injector (JT-60 NBI) is designed to inject 20 MW neutral hydrogen beam at energies of 70 ∼ 100 keV and the injection power decreases significantly at low energies (∼40 keV). For the extention of operation region aiming at the low density plasma heating and achieving H-mode by plasma periphery heating, increment of the injection power at low beam energies was required. The single-stage acceleration system was investigated in advance at the Prototype Injector Unit. From this result, the total injection power of 17 MW at 40 keV, 48 A per source was expected at the JT-60 NBI. This system was adopted in the JT-60 NBI from June, 1987 to July, 1987 and 17.6 MW neutral beam injection power was achieved. In the NB heating experiment, the H-mode transition phenomena was observed in JT-60 plasma. (author)
Introduction to ECR [electron cyclotron resonance] sources in electrostatic machines

International Nuclear Information System (INIS)

Olsen, D.K.

1989-01-01

Electron Cyclotron Resonance (ECR) ion source technology has developed rapidly since the original pioneering work of R. Geller and his group at Grenoble in the early 1970s. These ion sources are capable of producing intense beams of highly charged positive ions and are used extensively for cyclotron injection, linac injection, and atomic physics research. In this paper, the possible use of ECR heavy-ion sources in the terminals of electrostatic machines is discussed. The basic concepts of ECR sources are reviewed in the next section using the ORNL source as a model. The possible advantages of ECR sources over conventional negative ion injection and foil stripping are discussed in Section III. The last section describes the possible installation of an ECR source in a large machine such as the HHIRF 25-MV Pelletron. 6 refs., 4 figs., 1 tab
A Cooperative Approach to Virtual Machine Based Fault Injection

Energy Technology Data Exchange (ETDEWEB)

Naughton III, Thomas J [ORNL; Engelmann, Christian [ORNL; Vallee, Geoffroy R [ORNL; Aderholdt, William Ferrol [ORNL; Scott, Stephen L [Tennessee Technological University (TTU)

2017-01-01

Resilience investigations often employ fault injection (FI) tools to study the effects of simulated errors on a target system. It is important to keep the target system under test (SUT) isolated from the controlling environment in order to maintain control of the experiement. Virtual machines (VMs) have been used to aid these investigations due to the strong isolation properties of system-level virtualization. A key challenge in fault injection tools is to gain proper insight and context about the SUT. In VM-based FI tools, this challenge of target con- text is increased due to the separation between host and guest (VM). We discuss an approach to VM-based FI that leverages virtual machine introspection (VMI) methods to gain insight into the target s context running within the VM. The key to this environment is the ability to provide basic information to the FI system that can be used to create a map of the target environment. We describe a proof- of-concept implementation and a demonstration of its use to introduce simulated soft errors into an iterative solver benchmark running in user-space of a guest VM.
The association between neighborhood socioeconomic disadvantage and high-risk injection behavior among people who inject drugs.

Science.gov (United States)

DeCuir, Jennifer; Lovasi, Gina S; El-Sayed, Abdulrahman; Lewis, Crystal Fuller

2018-02-01

Although much research has been conducted on the determinants of HIV risk behavior among people who inject drugs (PWID), the influence of the neighborhood context on high-risk injection behavior remains understudied. To address this gap in the literature, we measured associations between neighborhood socioeconomic disadvantage and high-risk injection behavior, and determined whether these associations were modified by drug-related police activity and syringe exchange program (SEP) accessibility. Our sample was comprised of 484 pharmacy-recruited PWID in New York City. Measures of neighborhood socioeconomic disadvantage were created using data from the 2006-2010 American Community Survey. Associations with high-risk injection behavior were estimated using multivariable Poisson regression. Effect modification by drug-related police activity and SEP accessibility was assessed by entering cross-product terms into adjusted models of high-risk injection behavior. Neighborhood socioeconomic disadvantage was associated with decreased receptive syringe sharing and unsterile syringe use. In neighborhoods with high drug-related police activity, associations between neighborhood disadvantage and unsterile syringe use were attenuated to the null. In neighborhoods with high SEP accessibility, neighborhood disadvantage was associated with decreased acquisition of syringes from an unsafe source. PWID in disadvantaged neighborhoods reported safer injection behaviors than their counterparts in neighborhoods that were relatively better off. The contrasting patterns of effect modification by SEP accessibility and drug-related police activity support the use of harm reduction approaches over law enforcement-based strategies for the control of blood borne virus transmission among PWID in disadvantaged urban areas. Copyright © 2017 Elsevier B.V. All rights reserved.
High repetition rate driver circuit for modulation of injection lasers

International Nuclear Information System (INIS)

Dornan, B.R.; Goel, J.; Wolkstein, H.J.

1981-01-01

An injection laser modulator comprises a self-biased field effect transistor (FET) and an injection laser to provide a quiescent state during which lasing of the injection laser occurs in response to a high repetition rate signal of pulse coded modulation (pcm). The modulator is d.c. coupled to an input pulse source of pcm rendering it compatible with an input pulse referenced to ground and not being subject to voltage level shifting of the input pulse. The modulator circuit in its preferred and alternate embodiments provides various arrangements for high impedance input and low impedance output matching. In addition, means are provided for adjusting the bias of the FET as well as the bias of the injection laser
Evaluation of injection-well risk management in the Williston basin

International Nuclear Information System (INIS)

Michie, T.W.; Koch, C.A.

1991-01-01

This paper reports on a study of subsurface water-injection operations in the Williston geologic basin which demonstrated the practicality of incorporating risk management procedures into the regulation of underground injection control (UIC) programs. A realistic model of a computerized data base was developed to assess the maximum quantifiable risk that water from injection wells would reach an underground source of drinking water (USDW). In the Williston basin, the upper-bound probability of injection water escaping the wellbore and reaching a USDW is seven chances in 1 million well-years where surface casings cover the drinking-water aquifers. Where surface casings do not cover the USDW's, the probability is six chances in 1,000 well-years
Injection locking of optomechanical oscillators via acoustic waves

Science.gov (United States)

Huang, Ke; Hossein-Zadeh, Mani

2018-04-01

Injection locking is a powerful technique for synchronization of oscillator networks and controlling the phase and frequency of individual oscillators using similar or other types of oscillators. Here, we present the first demonstration of injection locking of a radiation-pressure driven optomechanical oscillator (OMO) via acoustic waves. As opposed to previously reported techniques (based on pump modulation or direct application of a modulated electrostatic force), injection locking of OMO via acoustic waves does not require optical power modulation or physical contact with the OMO and it can easily be implemented on various platforms. Using this approach we have locked the phase and frequency of two distinct modes of a microtoroidal silica OMO to a piezoelectric transducer (PZT). We have characterized the behavior of the injection locked OMO with three acoustic excitation configurations and showed that even without proper acoustic impedance matching the OMO can be locked to the PZT and tuned over 17 kHz with only -30 dBm of RF power fed to the PZT. The high efficiency, simplicity and scalability of the proposed approach paves the road toward a new class of photonic systems that rely on synchronization of several OMOs to a single or multiple RF oscillators with applications in optical communication, metrology and sensing. Beyond its practical applications, injection locking via acoustic waves can be used in fundamental studies in quantum optomechanics where thermal and optical isolation of the OMO are critical.
Efficacy of oral moxidectin against susceptible and resistant isolates of Dirofilaria immitis in dogs.

Science.gov (United States)

McTier, Tom L; Six, Robert H; Pullins, Aleah; Chapin, Sara; McCall, John W; Rugg, Douglas; Maeder, Steven J; Woods, Debra J

2017-11-09

Monthly topical and sustained-release injectable formulations of moxidectin are currently marketed; however, an oral formulation, while approved at a dose of 3 μg/kg, is not currently marketed in the United States. Although resistance of heartworms to all macrocyclic lactone (ML) heartworm preventives (ivermectin, milbemycin, selamectin and moxidectin) has been demonstrated, to date no data have been reported on the effectiveness of oral moxidectin against recent isolates of Dirofilaria immitis. A total of nine studies were conducted to determine the efficacy of moxidectin against a range of older and recently sourced heartworm isolates. Dogs (groups of three to eight) were inoculated with 50 D. immitis infective larvae (L3) from nine different isolates (MP3, Michigan, JYD-34, ZoeMO-2012, ZoeKy-2013, ZoeLA-2013, GCFL-2014, AMAL-2014 and ZoeAL-2015) and treated 28-30 days later with single oral doses of 3 μg/kg of moxidectin. Additionally, one group of dogs that was inoculated with JYD-34 was treated monthly for 3 consecutive months beginning 30 days post inoculation. Dogs were held for approximately 4 months after the initial (or only) treatment and then necropsied for recovery of adult heartworms. A single dose of 3 μg/kg of moxidectin was 100% effective in preventing the development of five of nine heartworm isolates (MP3, Michigan, ZoeKy, GCFL and ZoeAL isolates), confirming their susceptibility to oral moxidectin at this dose. MP3 and Michigan are isolates sourced from the field more than 9 years ago, while ZoeKy, ZoeAL and GCFL were isolated from the field within the past 2 to 3 years. Against JYD-34, ZoeMO, ZoeLA and AMAL isolates, a single dose of 3 μg/kg of moxidectin was not completely effective, with efficacies of 19%, 82%, 54% and 62%, respectively, demonstrating resistance of these heartworm isolates to oral moxidectin at this dosage. Three consecutive monthly doses of 3 μg/kg of moxidectin were also incompletely effective against the JYD
Efficacy of oral moxidectin against susceptible and resistant isolates of Dirofilaria immitis in dogs

Directory of Open Access Journals (Sweden)

Tom L. McTier

2017-11-01

Full Text Available Abstract Background Monthly topical and sustained-release injectable formulations of moxidectin are currently marketed; however, an oral formulation, while approved at a dose of 3 μg/kg, is not currently marketed in the United States. Although resistance of heartworms to all macrocyclic lactone (ML heartworm preventives (ivermectin, milbemycin, selamectin and moxidectin has been demonstrated, to date no data have been reported on the effectiveness of oral moxidectin against recent isolates of Dirofilaria immitis. Methods A total of nine studies were conducted to determine the efficacy of moxidectin against a range of older and recently sourced heartworm isolates. Dogs (groups of three to eight were inoculated with 50 D. immitis infective larvae (L3 from nine different isolates (MP3, Michigan, JYD-34, ZoeMO-2012, ZoeKy-2013, ZoeLA-2013, GCFL-2014, AMAL-2014 and ZoeAL-2015 and treated 28–30 days later with single oral doses of 3 μg/kg of moxidectin. Additionally, one group of dogs that was inoculated with JYD-34 was treated monthly for 3 consecutive months beginning 30 days post inoculation. Dogs were held for approximately 4 months after the initial (or only treatment and then necropsied for recovery of adult heartworms. Results A single dose of 3 μg/kg of moxidectin was 100% effective in preventing the development of five of nine heartworm isolates (MP3, Michigan, ZoeKy, GCFL and ZoeAL isolates, confirming their susceptibility to oral moxidectin at this dose. MP3 and Michigan are isolates sourced from the field more than 9 years ago, while ZoeKy, ZoeAL and GCFL were isolated from the field within the past 2 to 3 years. Against JYD-34, ZoeMO, ZoeLA and AMAL isolates, a single dose of 3 μg/kg of moxidectin was not completely effective, with efficacies of 19%, 82%, 54% and 62%, respectively, demonstrating resistance of these heartworm isolates to oral moxidectin at this dosage. Three consecutive monthly doses of 3 μg/kg of
Plasma heating by cluster injection: basic features and expected behaviour

International Nuclear Information System (INIS)

Bottiglioni, F.; Coutant, J.; Fois, M.

1976-08-01

The main components of a cluster injection line intended for plasma heating is briefly discussed, that is the beam source, the cluster ionizer and the accelerating tube, as well as the behavior of clusters interacting with a plasma. Outlines of the experiment of cluster injection into TFR, in progress at Fontenay-aux-Roses, and expected results will be presented and discussed all along the paper
Growth of locally isolated microalga in POME to produce lipid as alternative energy sources

Science.gov (United States)

Elvitriana; Munir, E.; Delvian; Wahyuningsih, H.

2018-04-01

Purpose of this study was to find the best growth of locally isolated microalgae that produce lipids from Palm Oil Mill Effluent (POME) as an alternative energy source. Microalgae was cultivated in POME in glass vessel at room temperature using a lighting intensity of 13,000 lux and continuously aeration for 24 and 12 hours, respectively. Biomass of microalgae were analyzed daily to get their growth by spectrophotometry at 624 nm wavelength, whereas Modified Bligh and Dyer method determined lipid content. Results show that the best growth occurred at 10% inoculum with lighting cycle and aeration of 24 hours (on/off) and resulting highest biomass content of 0.99 g dry weight/L followed by the decrease of organic substances in POME. The percentage reduction of COD, BOD, TSS, and oil at POME reached above 92%, while phosphate concentration reached 89.2%. Cultivation of microalgae in POME for 12 days showed its ability to reduce organic substances and nutrients in POME and produced biomass with lipid content of 35%. These results reached to the conclusion that locally isolated microalgae has an ability to treat POME safely for environment and POME can be used as a growing medium of microalgae that produces lipids.
A direct plasma injection system into an RFQ for clean and safe ion implantation

International Nuclear Information System (INIS)

Takeuchi, T.; Katayama, T.; Okamura, M.; Yano, K.; Sakumi, A.; Hattori, T.; Hayashizaki, N.; Jameson, R.A.

2002-01-01

A new injection system, direct plasma injection system, was tested and its principle was proved successfully. We found that one of advantages of this injection system was efficient consumption of source materials. Large portions of induced ions can be injected into a first stage accelerator. This feature is quite useful for ion implantation applications, because toxic exhaust gas can be eliminated. In order to utilize this system for industrial application, the feasibility of a boron injection scheme using a Nd:YAG laser system was investigated
Isolation and characterization of (15Z)-lycopene thermally generated from a natural source

Energy Technology Data Exchange (ETDEWEB)

Takehara, Munenori, E-mail: takehara@mat.usp.ac.jp [Department of Materials Science, The University of Shiga Prefecture, Hassaka, Hikone 522-8533 (Japan); Kuwa, Takahiro; Inoue, Yoshinori; Kitamura, Chitoshi [Department of Materials Science, The University of Shiga Prefecture, Hassaka, Hikone 522-8533 (Japan); Honda, Masaki [Research & Development Division, Kagome Co., Ltd., Nishitomiyama, Nasushiobara 329-2762 (Japan)

2015-11-06

(15Z)-Lycopene was prepared by thermal isomerization of (all-E)-lycopene derived from tomatoes, and isolated by using a series of chromatographies. The fine red crystalline powder of (15Z)-lycopene was obtained from 556 mg of (all-E)-lycopene with a yield of 0.6 mg (purity: reversed-phase HPLC, 97.2%; normal-phase HPLC, ≥99.9%), and {sup 1}H and {sup 13}C NMR spectra of the isomer were fully assigned. More refined computational analyses that considered differences in the energy levels of the conformers involved in isomerization have also determined the stabilities of (15Z)-lycopene and other geometric isomers, along with the activation energies during isomerization from the all-E form. The fine control of conditions for HPLC separation and an advanced theoretical insight into geometric isomerization have led to the discovery of the 15Z-isomer generated from a natural source. - Highlights: • (15Z)-lycopene, isomerized from the all-E form of a natural source, was purified. • The obtained (15Z)-lycopene was structurally identified by an NMR analysis. • A modified theoretical study accounted for the generation of the 15Z-isomer. • This study demonstrated the occurrence of the isomer from a natural origin.
Isolation and characterization of (15Z)-lycopene thermally generated from a natural source

International Nuclear Information System (INIS)

Takehara, Munenori; Kuwa, Takahiro; Inoue, Yoshinori; Kitamura, Chitoshi; Honda, Masaki

2015-01-01

(15Z)-Lycopene was prepared by thermal isomerization of (all-E)-lycopene derived from tomatoes, and isolated by using a series of chromatographies. The fine red crystalline powder of (15Z)-lycopene was obtained from 556 mg of (all-E)-lycopene with a yield of 0.6 mg (purity: reversed-phase HPLC, 97.2%; normal-phase HPLC, ≥99.9%), and 1 H and 13 C NMR spectra of the isomer were fully assigned. More refined computational analyses that considered differences in the energy levels of the conformers involved in isomerization have also determined the stabilities of (15Z)-lycopene and other geometric isomers, along with the activation energies during isomerization from the all-E form. The fine control of conditions for HPLC separation and an advanced theoretical insight into geometric isomerization have led to the discovery of the 15Z-isomer generated from a natural source. - Highlights: • (15Z)-lycopene, isomerized from the all-E form of a natural source, was purified. • The obtained (15Z)-lycopene was structurally identified by an NMR analysis. • A modified theoretical study accounted for the generation of the 15Z-isomer. • This study demonstrated the occurrence of the isomer from a natural origin.

Molecular epidemiology of HIV type 1 infection in Iran: genomic evidence of CRF35_AD predominance and CRF01_AE infection among individuals associated with injection drug use.

Science.gov (United States)

Jahanbakhsh, Fatemeh; Ibe, Shiro; Hattori, Junko; Monavari, Seyed Hamid Reza; Matsuda, Masakazu; Maejima, Masami; Iwatani, Yasumasa; Memarnejadian, Arash; Keyvani, Hossein; Azadmanesh, Kayhan; Sugiura, Wataru

2013-01-01

To understand the molecular epidemiology of HIV-1 infection in Iran, we conducted the first study to analyze the genome sequence of Iranian HIV-1 isolates. For this cross-sectional study, we enrolled 10 HIV-1-infected individuals associated with injection drug use from Tehran, Shiraz, and Kermanshah. Near full-length genome sequences obtained from their plasma samples were used for phylogenetic tree and similarity plotting analyses. Among 10 isolates, nine were clearly identified as CRF35_AD and the remaining one as CRF01_AE. Interestingly, five of our Iranian CRF35_AD isolates made two clusters with 10 Afghan CRF35_AD isolates in a phylogenetic tree, indicating epidemiological connections among injection drug users in Iran and Afghanistan. In contrast, our CRF01_AE isolate had no genetic relationship with any other CRF01_AE isolates worldwide, even from Afghanistan. This study provides the first genomic evidence of HIV-1 CRF35_AD predominance and CRF01_AE infection among individuals associated with injection drug use in Iran.
Experimental infection of rainbow trout Oncorhynchus mykiss with viral haemorrhagic septicaemia virus isolates from European marine and farmed fishes

DEFF Research Database (Denmark)

Skall, Helle Frank; Slierendrecht, W.J.; King, J.A.

2004-01-01

The susceptibility of rainbow trout Oncorhynchus mykiss to infection with various isolates of viral haemorrhagic septicaemia virus (VHSV) was examined. A total of 8 experiments with rainbow trout ranging from 0.6 to 6.2 g was conducted for 139 isolates originating from wild marine fishes in Europ......The susceptibility of rainbow trout Oncorhynchus mykiss to infection with various isolates of viral haemorrhagic septicaemia virus (VHSV) was examined. A total of 8 experiments with rainbow trout ranging from 0.6 to 6.2 g was conducted for 139 isolates originating from wild marine fishes...... in European waters (115 isolates), farmed turbot from Scotland and Ireland (2 isolates), and farmed rainbow trout (22 isolates). The isolates were tested by immersion and/or intraperitoneal injection either as pooled or single isolates. The isolates from wild marine fishes did not cause mortality by immersion...... while some of the isolates caused mortality when injected. All VHSV isolates from farmed rainbow trout caused significant mortality by immersion. Currently, pathogenicity trials are the only way to differentiate VHSV isolates from wild marine fishes and farmed rainbow trout. The 2 farmed turbot isolates...
Radiotracer investigations in oil production and water injection wells

International Nuclear Information System (INIS)

Eapen, A.C.; Jain, S.K.; Kirti

1977-01-01

Injection of gamma emitting radiotracers into oil wells followed by logging provides information on several aspects such as the identification of zones of seepage of water in the water injection wells and also the location of source of water entering oil producting wells. The experience gained in the application of bromine-82 and rubidium-86 as radiotracers in such studies at the Ankleshwar and Kalol oil fields in Gujarat and Nazira in Assam has been briefly reported. (author)
Increase of the positive ion source power in JT-60 NBI

International Nuclear Information System (INIS)

Kawai, Mikito; Akino, Noboru; Ebisawa, Noboru

1998-09-01

Neutral Beam Injection (NBI) heating experiment in JT-60 started in 1986, and the rated injection power of 20MW at 75keV with hydrogen was achieved after several month operation. In 1991, the ion sources and power supply had been upgraded for a higher beam energy up to 120keV with deuterium, following which the ion source operation re-started aiming for an injection power of 40MW at 110keV. In the operation, the beam acceleration voltage was tried to increase by modifying the ion source structure against the break-down which occurred frequently in the ion source. The beam acceleration was, however, unstable in a beam energy range of more than 105keV because of voltage-holding deterioration in the accelerator. Therefore we changed the strategy to increase the injection power: i.e. we tried to increase the beam current with keeping the beam energy. The structure of the source has been modified to be operated in a high current regime. As a result, the deuterium neutral beam injection of 40MW at 91-96keV was achieved in July 1996. (author)
MATLAB-based algorithm to estimate depths of isolated thin dike-like sources using higher-order horizontal derivatives of magnetic anomalies.

Science.gov (United States)

Ekinci, Yunus Levent

2016-01-01

This paper presents an easy-to-use open source computer algorithm (code) for estimating the depths of isolated single thin dike-like source bodies by using numerical second-, third-, and fourth-order horizontal derivatives computed from observed magnetic anomalies. The approach does not require a priori information and uses some filters of successive graticule spacings. The computed higher-order horizontal derivative datasets are used to solve nonlinear equations for depth determination. The solutions are independent from the magnetization and ambient field directions. The practical usability of the developed code, designed in MATLAB R2012b (MathWorks Inc.), was successfully examined using some synthetic simulations with and without noise. The algorithm was then used to estimate the depths of some ore bodies buried in different regions (USA, Sweden, and Canada). Real data tests clearly indicated that the obtained depths are in good agreement with those of previous studies and drilling information. Additionally, a state-of-the-art inversion scheme based on particle swarm optimization produced comparable results to those of the higher-order horizontal derivative analyses in both synthetic and real anomaly cases. Accordingly, the proposed code is verified to be useful in interpreting isolated single thin dike-like magnetized bodies and may be an alternative processing technique. The open source code can be easily modified and adapted to suit the benefits of other researchers.
Antibiotic resistance in Escherichia coli isolates from roof-harvested rainwater tanks and urban pigeon faeces as the likely source of contamination.

Science.gov (United States)

Chidamba, Lizyben; Korsten, Lise

2015-07-01

The objective of this study was to investigate the risks associated with the use of roof-harvested rainwater (RHRW) and the implication of pigeons as the most likely source of contamination by testing for antibiotic resistance profiles of Escherichia coli. A total of 239 E. coli were isolated from thirty fresh pigeon faecal samples (130 isolates), 11 RHRW tanks from three sites in Pretoria (78) and two in Johannesburg (31). E. coli isolates were tested against a panel of 12 antibiotics which included ampicillin, amoxicillin, amikacin, cefoxitin, ceftriaxone, chloramphenicol, ciprofloxacin, cotrimoxazole, enrofloxacin, gentamicin, nalidixic acid and tetracycline. In all samples, resistance to ampicillin (22.7.9%), gentamicin (23.6%), amikacin (24%), tetracycline (17.4) and amoxicillin (16.9%) were the most frequently encountered form of resistance. However, a relatively higher proportion of isolates from pigeon faeces (67.3%) were antibiotic resistant than those from RHRW (53.3%). The highest number of phenotypes was observed for single antibiotics, and no single antibiotic resistance was observed for chloramphenicol, ceftriaxone, gentamicin, cefoxitin, cotrimoxazole, although they were detected in multiple antibiotic resistance (MAR) phenotypes. The highest multiple antibiotic resistance (MAR) phenotypes were observed for a combination of four antibiotics, on isolates from JHB (18.8%), pigeon faeces (15.2%) and Pretoria (5.1%). The most abundant resistance phenotype to four antibiotics, Ak-Gm-Cip-T was dominated by isolates from pigeon faeces (6.8%) with Pretoria and Johannesburg isolates having low proportions of 1.3 and 3.1%, respectively. Future studies should target isolates from various environmental settings in which rainwater harvesting is practiced and the characterisation of the antibiotic resistance determinant genes among the isolates.
Water injection profiling

International Nuclear Information System (INIS)

Arnold, D.M.

1982-01-01

A method of neutron-gamma logging is described, in which water, injected in a cased well borehole with peforations, is irradiated with neutrons of 10 MeV or greater, and subsequent gamma radiation is detected by a pair of detectors along the borehole. Counting rates of detectors are analyzed in terms of two gamma ray energy windows. Linear flow velocity of fluid moving downward within the casing is used in conjunction with count rate data to determine volume flow rates of water moving in other directions. Apparatus includes a sonde with a neutron source and appropriate gamma sensors
Effects of moxifloxacin exposure on the conjunctival flora and antibiotic resistance profile following repeated intravitreal injections

Directory of Open Access Journals (Sweden)

Mustafa Ataş

2014-10-01

Full Text Available AIM:To evaluate the effects of moxifloxacin exposure on the conjunctival flora and antibiotic resistance profile following repeated intravitreal injections.METHODS:Seventy-two eyes of 36 patients [36 eyes in control group, 36 eyes in intravitreal injection (IVI group] were enrolled in the study. All the eyes had at least one IVI and had diabetic macular edema (DME or age-related macular degeneration (ARMD. Moxifloxacin was prescribed to all the patients four times a day for five days following injection. Conjunctival cultures were obtained from the lower fornix via standardized technique with every possible effort made to minimize contamination from the lids, lashes, or skin. Before the application of any ophthalmic medication, conjunctival cultures were obtained from both eyes using sterile cotton culture. An automated microbiology system was used to identify the growing bacteria and determine antibiotic sensitivity. RESULTS:The bacterial cultures were isolated from 72 eyes of 36 patients, sixteen of whom patients (44.4% were male and twenty (55.6% were female. Average age was 68.4±9.0 (range 50-86. The average number of injections before taking cultures was 3.1+1.0. Forty-eight (66.7% of 72 eyes had at least one significant organism. There was no bacterial growth in 8 (20.5% of IVI eyes and in 16 (44.4% of control eyes (P=0.03. Of the bacteria isolated from culture, 53.8% of coagulase negative staphylococci (CoNS in IVI eyes and 47.2% CoNS in control eyes. This difference between IVI eyes and control eyes about bacteria isolated from culture was not statistically significant (P=0.2. Eleven of 25 bacteria (44.0% isolated from IVI eyes and 11 (57.9% of 19 bacteria isolated from control eyes were resistant to oxacillin. The difference in frequency of moxifloxacine resistance between two groups was not statistically significant (12.0% in IVI eyes and 21.1% in control eyes (P=0.44. There were no cases of resistance to vancomycin, teicoplanin and
MgO by injection CVD

International Nuclear Information System (INIS)

Abrutis, A.; Kubilius, V.; Teiserkis, A.; Bigelyte, V.; Vengalis, B.; Jukna, A.; Butkute, R.

1997-01-01

Epitaxial YBa 2 Cu 3 O 7 layers with 45 in-plane orientation have been grown by injection CVD on MgO substrates polished off-axis to within 1.4-1.9 of the [100] direction. This new single-source CVD process is based on computer-controlled injection of precise microdoses of a metal-organic precursor solution into a CVD reactor. A wide range of solution compositions was tested to investigate compositional effects on phase purity, surface morphology, texturing and superconducting properties of the prepared films. The highest quality films with pure 45 texture had a smooth surface, zero resistance T c (R=0) of 88-89 K, and critical current density J c (77 K) above 10 6 A/cm 2 . (orig.) and critical current density J c (77 K) above 10 6 A/cm 2 . (orig.)
Water injection profiling by nuclear logging

International Nuclear Information System (INIS)

Arnold, D.M.

1980-01-01

This invention relates to nuclear logging techniques for determining the volume flow rates and flow directions of injected water moving behind a wellbore casing. The apparatus includes a sonde equipped with a neutron source and dual radiation detectors. Oxygen in the neutron irradiated water is transmitted to 16 N and the resultant primary and Compton scattered gamma rays are detected in two energy windows by both detectors. Count rate data is analysed in terms of the windows to obtain linear flow velocities for water flow within and behind the casing. Volume flow rates are determined for upward and downward flow, and horizontal volume flow into the surrounding formation is calculated. A complete injection profile may thus be obtained. (U.K.)
Shared Mycobacterium avium genotypes observed among unlinked clinical and environmental isolates

Science.gov (United States)

Our understanding of the sources of Mycobacterium avium infection is partially based on genotypic matching of pathogen isolates from cases and environmental sources. These approaches assume that genotypic identity is rare in isolates from unlinked cases or sources. To test this, ...
Comparison of Protein Extracts from Various Unicellular Green Sources.

Science.gov (United States)

Teuling, Emma; Wierenga, Peter A; Schrama, Johan W; Gruppen, Harry

2017-09-13

Photosynthetic unicellular organisms are considered as promising alternative protein sources. The aim of this study is to understand the extent to which these green sources differ with respect to their gross composition and how these differences affect the final protein isolate. Using mild isolation techniques, proteins were extracted and isolated from four different unicellular sources (Arthrospira (spirulina) maxima, Nannochloropsis gaditana, Tetraselmis impellucida, and Scenedesmus dimorphus). Despite differences in protein contents of the sources (27-62% w/w) and in protein extractability (17-74% w/w), final protein isolates were obtained that had similar protein contents (62-77% w/w) and protein yields (3-9% w/w). Protein solubility as a function of pH was different between the sources and in ionic strength dependency, especially at pH < 4.0. Overall, the characterization and extraction protocol used allows a relatively fast and well-described isolation of purified proteins from novel protein sources.
Investigating Salmonella Eko from Various Sources in Nigeria by Whole Genome Sequencing to Identify the Source of Human Infections.

Directory of Open Access Journals (Sweden)

Pimlapas Leekitcharoenphon

Full Text Available Twenty-six Salmonella enterica serovar Eko isolated from various sources in Nigeria were investigated by whole genome sequencing to identify the source of human infections. Diversity among the isolates was observed and camel and cattle were identified as the primary reservoirs and the most likely source of the human infections.
Antibiotic resistance profiles of Escherichia coli isolated from different water sources in the Mmabatho locality, Northwest Province, South Africa

Directory of Open Access Journals (Sweden)

C. Njie Ateba

2010-03-01

Full Text Available The antibiotic resistance profiles of Escherichia coli (E. coli, isolated from different water sources in the Mmabatho locality were evaluated. Water samples were collected from the local wastewater- and water-treatment plants, the Modimola Dam and homes in the area, and then analysed for the presence of E. coli, using standard methods. Presumptive isolates obtained were confirmed by the analytical profile index test. Antibiotic susceptibility testing was performed by the disc diffusion method. Of the 230 E. coli isolates tested, marked antibiotic resistances (over 70% were observed for erythromycin, tetracycline, ampicillin, chloramphenicol and norfloxacin. Multiple antibiotic resistance patterns were also compiled. Overall, the phenotype T-Ap-E was frequent for E. coli isolated from the local wastewater and water-treatment plants, Modimola Dam and tap water. Cluster analysis performed showed a unique antibiotic resistance pattern which suggested a link between isolates from all sampling points. The findings indicated that improper wastewater treatment may have a potential impact on the dissemination and survival of E. coli, as well as other pathogenic bacteria in water for human and animal consumption. This may result in water- and food-borne disease outbreaks with a negative effect on antibiotic therapy.
CFD analysis of poison injection in AHWR calandria

International Nuclear Information System (INIS)

Kansal, A.K.; Kamble, M.T.; Maheshwari, N.K.; Vijayan, P.K.

2014-01-01

The present work intends to give details of design and performance validation of SDS-2. The performance is evaluated on the basis of dispersion of poison in calandria in a given period of time. Location of injection tube and injection holes, size of jet hole and number of holes are some of the design parameters which greatly affect dispersion of poison in calandria. A Computational Fluid Dynamic (CFD) study for axial and radial injection of poison was carried out using open source CFD code OpenFOAM. CFD benchmarking was done using experiments performed by Johari (Johari et al. 1997) to identify suitable turbulence model for this problem. An experimental facility simulating poison injection in moderator in presence of calandria tubes was used to further validate the CFD model is shown in the paper. CFD analysis was carried out for axial as well as radial injection for AHWR geometry. CFD analysis using OpenFOAM has been carried out to study high pressure poison injection for single jet of Shut Down System - 2 (SDS- 2) of Advanced Heavy Water Reactor (AHWR) for various design options. CFD model used in analysis have been validated with experimental data available in literature as well as experiments performed for AHWR specific geometry. Various turbulence models are tested and their adequacy for such flow problems has been established. The CFD model is then used to simulate poison injection for two design options for AHWR and their performance is compared. (author)
Ribotyping for differentiating Flavobacterium meningosepticum isolates from clinical and environmental sources

DEFF Research Database (Denmark)

Colding, H; Bangsborg, J; Fiehn, N E

1994-01-01

RI), a discriminatory index of 0.95 to 0.97 was found. The value of ribotyping in an epidemiological setting was assessed for three clinical isolates of F. meningosepticum from an outbreak of meningitis and bacteremia in the neonatal intensive care unit, Rigshospitalet, Copenhagen, Denmark. The three clinical isolates...
Geographically isolated wetlands: Rethinking a misnomer

Science.gov (United States)

Mushet, David M.; Calhoun, Aram J.K.; Alexander, Laurie C.; Cohen, Matthew J.; DeKeyser, Edward S.; Fowler, Laurie G.; Lane, Charles R.; Lang, Megan W.; Rains, Mark C.; Walls, Susan

2015-01-01

We explore the category “geographically isolated wetlands” (GIWs; i.e., wetlands completely surrounded by uplands at the local scale) as used in the wetland sciences. As currently used, the GIW category (1) hampers scientific efforts by obscuring important hydrological and ecological differences among multiple wetland functional types, (2) aggregates wetlands in a manner not reflective of regulatory and management information needs, (3) implies wetlands so described are in some way “isolated,” an often incorrect implication, (4) is inconsistent with more broadly used and accepted concepts of “geographic isolation,” and (5) has injected unnecessary confusion into scientific investigations and discussions. Instead, we suggest other wetland classification systems offer more informative alternatives. For example, hydrogeomorphic (HGM) classes based on well-established scientific definitions account for wetland functional diversity thereby facilitating explorations into questions of connectivity without an a priori designation of “isolation.” Additionally, an HGM-type approach could be used in combination with terms reflective of current regulatory or policymaking needs. For those rare cases in which the condition of being surrounded by uplands is the relevant distinguishing characteristic, use of terminology that does not unnecessarily imply isolation (e.g., “upland embedded wetlands”) would help alleviate much confusion caused by the “geographically isolated wetlands” misnomer.
Ion sources for initial use at the Holifield radioactive ion beam facility

International Nuclear Information System (INIS)

Alton, G.D.

1994-01-01

The Holifield Radioactive Ion Beam Facility (HRIBF) now under construction at the Oak Ridge National Laboratory will use the 25-MV tandem accelerator for the acceleration of radioactive ion beams to energies appropriate for research in nuclear physics; negative ion beams are, therefore, required for injection into the tandem accelerator. Because charge exchange is an efficient means for converting initially positive ion beams to negative ion beams, both positive and negative ion sources are viable options for use at the facility; the choice of the type of ion source will depend on the overall efficiency for generating the radioactive species of interest. A high-temperature version of the CERN-ISOLDE positive ion source has been selected and a modified version of the source designed and fabricated for initial use at the HRIBF because of its low emittance, relatively high ionization efficiencies and species versatility, and because it has been engineered for remote installation, removal and servicing as required for safe handling in a high-radiation-level ISOL facility. Prototype plasma-sputter negative ion sources and negative surfaceionization sources are also under design consideration for generating negative radioactive ion beams from high electron-affinity elements. A brief review of the HRIBF will be presented, followed by a detailed description of the design features, operational characteristics, ionization efficiencies, and beam qualities (emittances) of these sources
Numerical simulation in steam injection process by a mechanistic approach

Energy Technology Data Exchange (ETDEWEB)

De Souza, J.C.Jr.; Campos, W.; Lopes, D.; Moura, L.S.S. [Petrobras, Rio de Janeiro (Brazil)

2008-10-15

Steam injection is a common thermal recovery method used in very viscous oil reservoirs. The method involves the injection of heat to reduce viscosity and mobilize oil. A steam generation and injection system consists primarily of a steam source, distribution lines, injection wells and a discarding tank. In order to optimize injection and improve the oil recovery factor, one must determine the parameters of steam flow such as pressure, temperature and steam quality. This study focused on developing a unified mathematical model by means of a mechanistic approach for two-phase steam flow in pipelines and wells. The hydrodynamic and heat transfer mechanistic model was implemented in a computer simulator to model the parameters of steam injection while trying to avoid the use of empirical correlations. A marching algorithm was used to determine the distribution of pressure and temperature along the pipelines and wellbores. The mathematical model for steam flow in injection systems, developed by a mechanistic approach (VapMec) performed well when the simulated values of pressures and temperatures were compared with the values measured during field tests. The newly developed VapMec model was incorporated in the LinVap-3 simulator that constitutes an engineering supporting tool for steam injection wells operated by Petrobras. 23 refs., 7 tabs., 6 figs.
Shared Mycobacterium avium genotypes observed among unlinked clinical and environmental isolates*

Science.gov (United States)

Our understanding of the sources of Mycobacterium avium infection is partially based on genotypic matching of pathogen isolates from cases and environmental sources. These approaches assume that genotypic identity is rare in isolates from unlinked cases or sources. To test this a...

Injection of radioactive waste by hydraulic fracturing at West Valley, New York. Volume 2. Text

International Nuclear Information System (INIS)

1978-05-01

Results of a preliminary study are presented of the technical feasibility of radioactive waste disposal by hydraulic fracturing and injection into shale formations below the Nuclear Fuel Services Incorporated site at West Valley, New York. At this time there are approximately 600,000 gallons of high level neutralized Purex waste, including both the supernate (liquid) and sludge, and a further 12,000 gallons of acidic Thorex waste stored in tanks at the West Valley facilities. This study assesses the possibility of combining these wastes in a suitable grout mixture and then injecting them into deep shale formations beneath the West Valley site as a means of permanent disposal. The preliminary feasibility assessment results indicated that at the 850 to 1,250 feet horizons, horizontal fracturing and injection could be effectively achieved. However, a detailed safety analysis is required to establish the acceptability of the degree of isolation. The principal concerns regarding isolation are due to existing and possible future water supply developments within the area and the local effects of the buried valley. In addition, possible future natural gas developments are of concern. The definition of an exclusion zone may be appropriate to avoid problems with these developments. The buried valley may require the injections to be limited to the lower horizon depending on the results of further investigations
Biofilm-Forming Abilities of Listeria monocytogenes Serotypes Isolated from Different Sources

Science.gov (United States)

Doijad, Swapnil P.; Barbuddhe, Sukhadeo B.; Garg, Sandeep; Poharkar, Krupali V.; Kalorey, Dewanand R.; Kurkure, Nitin V.; Rawool, Deepak B.; Chakraborty, Trinad

2015-01-01

A total of 98 previously characterized and serotyped L. monocytogenes strains, comprising 32 of 1/2a; 20 of 1/2b and 46 of 4b serotype, from clinical and food sources were studied for their capability to form a biofilm. The microtiter plate assay revealed 62 (63.26%) strains as weak, 27 (27.55%) strains as moderate, and 9 (9.18%) strains as strong biofilm formers. Among the strong biofilm formers, 6 strains were of serotype 1/2a and 3 strains were of serotype 1/2b. None of the strain from 4b serotype exhibited strong biofilm formation. No firm correlation (p = 0.015) was noticed between any serotype and respective biofilm formation ability. Electron microscopic studies showed that strong biofilm forming isolates could synthesize a biofilm within 24 h on surfaces important in food industries such as stainless steel, ceramic tiles, high-density polyethylene plastics, polyvinyl chloride pipes, and glass. Cell enumeration of strong, moderate, and weak biofilm was performed to determine if the number of cells correlated with the biofilm-forming capabilities of the isolates. Strong, moderate, and weak biofilm showed 570±127× 103 cells/cm2, 33±26× 103 cells/cm2, 5±3× 103 cells/cm2, respectively, indicating that the number of cells was directly proportional to the strength of the biofilm. The hydrophobicity index (HI) analysis revealed higher hydrophobicity with an increased biofilm formation. Fatty acid methyl esterase analysis revealed the amount of certain fatty acids such as iso-C15:0, anteiso-C15:0, and anteiso-C17:0 fatty acids correlated with the biofilm-forming capability of L. monocytogenes. This study showed that different strains of L. monocytogenes form biofilm of different intensities which did not completely correlate with their serotype; however, it correlated with the number of cells, hydrophobicity, and amount of certain fatty acids. PMID:26360831
Biofilm-Forming Abilities of Listeria monocytogenes Serotypes Isolated from Different Sources.

Directory of Open Access Journals (Sweden)

Swapnil P Doijad

Full Text Available A total of 98 previously characterized and serotyped L. monocytogenes strains, comprising 32 of 1/2a; 20 of 1/2b and 46 of 4b serotype, from clinical and food sources were studied for their capability to form a biofilm. The microtiter plate assay revealed 62 (63.26% strains as weak, 27 (27.55% strains as moderate, and 9 (9.18% strains as strong biofilm formers. Among the strong biofilm formers, 6 strains were of serotype 1/2a and 3 strains were of serotype 1/2b. None of the strain from 4b serotype exhibited strong biofilm formation. No firm correlation (p = 0.015 was noticed between any serotype and respective biofilm formation ability. Electron microscopic studies showed that strong biofilm forming isolates could synthesize a biofilm within 24 h on surfaces important in food industries such as stainless steel, ceramic tiles, high-density polyethylene plastics, polyvinyl chloride pipes, and glass. Cell enumeration of strong, moderate, and weak biofilm was performed to determine if the number of cells correlated with the biofilm-forming capabilities of the isolates. Strong, moderate, and weak biofilm showed 570±127× 103 cells/cm2, 33±26× 103 cells/cm2, 5±3× 103 cells/cm2, respectively, indicating that the number of cells was directly proportional to the strength of the biofilm. The hydrophobicity index (HI analysis revealed higher hydrophobicity with an increased biofilm formation. Fatty acid methyl esterase analysis revealed the amount of certain fatty acids such as iso-C15:0, anteiso-C15:0, and anteiso-C17:0 fatty acids correlated with the biofilm-forming capability of L. monocytogenes. This study showed that different strains of L. monocytogenes form biofilm of different intensities which did not completely correlate with their serotype; however, it correlated with the number of cells, hydrophobicity, and amount of certain fatty acids.
Improved oil recovery using bacteria isolated from North Sea petroleum reservoirs

Energy Technology Data Exchange (ETDEWEB)

Davey, R.A.; Lappin-Scott, H. [Univ. of Exeter (United Kingdom)

1995-12-31

During secondary oil recovery, water is injected into the formation to sweep out the residual oil. The injected water, however, follows the path of least resistance through the high-permeability zones, leaving oil in the low-permeability zones. Selective plugging of these their zones would divert the waterflood to the residual oil and thus increase the life of the well. Bacteria have been suggested as an alternative plugging agent to the current method of polymer injection. Starved bacteria can penetrate deeply into rock formations where they attach to the rock surfaces, and given the right nutrients can grow and produce exo-polymer, reducing the permeability of these zones. The application of microbial enhanced oil recovery has only been applied to shallow, cool, onshore fields to date. This study has focused on the ability of bacteria to enhance oil recovery offshore in the North Sea, where the environment can be considered extreme. A screen of produced water from oil reservoirs (and other extreme subterranean environments) was undertaken, and two bacteria were chosen for further work. These two isolates were able to grow and survive in the presence of saline formation waters at a range of temperatures above 50{degrees}C as facultative anaerobes. When a solution of isolates was passed through sandpacks and nutrients were added, significant reductions in permeabilities were achieved. This was confirmed in Clashach sandstone at 255 bar, when a reduction of 88% in permeability was obtained. Both isolates can survive nutrient starvation, which may improve penetration through the reservoir. Thus, the isolates show potential for field trials in the North Sea as plugging agents.
Enhancement of mouse germ cell-associated genes expression by injection of human umbilical cord mesenchymal stem cells into the testis of chemical-induced azoospermic mice

Directory of Open Access Journals (Sweden)

Rui-Feng Yang

2014-10-01

Full Text Available Various methods are currently under investigation to preserve fertility in males treated with high-dose chemotherapy and radiation for malignant and nonmalignant disorders. Human umbilical cord mesenchymal stem cells (HUC-MSCs, which possess potent immunosuppressive function and secrete various cytokines and growth factors, have the potential clinical applications. As a potential alternative, we investigate whether injection of HUC-MSCs into the interstitial compartment of the testes to promote spermatogenic regeneration efficiently. HUC-MSCs were isolated from different sources of umbilical cords and injected into the interstitial space of one testis from 10 busulfan-treated mice (saline and HEK293 cells injections were performed in a separate set of mice and the other testis remained uninjected. Three weeks after MSCs injection, Relative quantitative reverse transcription polymerase chain reaction was used to identify the expression of 10 of germ cell associated, which are all related to meiosis, demonstrated higher levels of spermatogenic gene expression (2-8 fold in HUC-MSCs injected testes compared to the contralateral uninjected testes (five mice. Protein levels for germ cell-specific genes, miwi, vasa and synaptonemal complex protein (Scp3 were also higher in MSC-treated testes compared to injected controls 3 weeks after treatment. However, no different expression was detected in saline water and HEK293 cells injection control group. We have demonstrated HUC-MSCs could affect mouse germ cell-specific genes expression. The results also provide a possibility that the transplanted HUC-MSCs may promote the recovery of spermatogenesis. This study provides further evidence for preclinical therapeutic effects of HUC-MSCs, and explores a new approach to the treatment of azoospermia.
Experimental Investigation into Suitable Process Conditions for Plastic Injection Molding of Thin-Sheet Parts

Directory of Open Access Journals (Sweden)

Dyi-Cheng Chen

2014-04-01

Full Text Available This study performs an experimental investigation into the effects of the process parameters on the surface quality of injection molded thin-sheet thermoplastic components. The investigations focus specifically on the shape, number and position of the mold gates, the injection pressure and the injection rate. It can be seen that the gravity force entering point improved filling of the cavity for the same forming time and injection pressure. Moreover, it shows the same injection pressure and packing time, the taper-shape gate yields a better surface appearance than the sheet-shape gate. The experimental results provide a useful source of reference in suitable the process conditions for the injection molding of thin-sheet plastic components.
Molecular characterization of bacteriophages for microbial source tracking in Korea.

Science.gov (United States)

Lee, Jung Eun; Lim, Mi Young; Kim, Sei Yoon; Lee, Sunghee; Lee, Heetae; Oh, Hyun-Myung; Hur, Hor-Gil; Ko, Gwangpyo

2009-11-01

We investigated coliphages from various fecal sources, including humans and animals, for microbial source tracking in South Korea. Both somatic and F+-specific coliphages were isolated from 43 fecal samples from farms, wild animal habitats, and human wastewater plants. Somatic coliphages were more prevalent and abundant than F+ coliphages in all of the tested fecal samples. We further characterized 311 F+ coliphage isolates using RNase sensitivity assays, PCR and reverse transcription-PCR, and nucleic acid sequencing. Phylogenetic analyses were performed based on the partial nucleic acid sequences of 311 F+ coliphages from various sources. F+ RNA coliphages were most prevalent among geese (95%) and were least prevalent in cows (5%). Among the genogroups of F+ RNA coliphages, most F+ coliphages isolated from animal fecal sources belonged to either group I or group IV, and most from human wastewater sources were in group II or III. Some of the group I coliphages were present in both human and animal source samples. F+ RNA coliphages isolated from various sources were divided into two main clusters. All F+ RNA coliphages isolated from human wastewater were grouped with Qbeta-like phages, while phages isolated from most animal sources were grouped with MS2-like phages. UniFrac significance statistical analyses revealed significant differences between human and animal bacteriophages. In the principal coordinate analysis (PCoA), F+ RNA coliphages isolated from human waste were distinctively separate from those isolated from other animal sources. However, F+ DNA coliphages were not significantly different or separate in the PCoA. These results demonstrate that proper analysis of F+ RNA coliphages can effectively distinguish fecal sources.
The effect of cigarette smoke on the metabolism of arachidonic acid in isolated hamster lungs

International Nuclear Information System (INIS)

Maennistoe, J.; Toivonen, H.; Hartiala, J.; Bakhle, Y.S.; Uotila, P.

1981-01-01

The effects of cigarette smoke on the metabolism of exogenous arachidonic acid (AA) were investigated in isolated hamster lungs. Arachidonate was injected into the pulmonary circulation and the metabolites were analysed from the nonrecirculating perfusion effluent by thin layer chromatography. After the pulmonary injection of 66 nmol of 14C-AA about 20% of the injected radioactivity appeared in the perfusion effluent mostly as metabolites in six minutes. When isolated lungs were ventilated with cigarette smoke during the perfusion, the amounts of PGF2 alpha, PGE2 and two unidentified metabolite groups increased in the lung effluent. In two other experimental series hamsters were exposed to cigarette smoke before the lung perfusion either once for 30 min or during one hour daily for ten consecutive days. Neither pre-exposures caused any changes in the amounts of arachidonate metabolites in the lung effluent
Non-injection Drug Use and Injection Initiation Assistance among People Who Inject Drugs in Tijuana, Mexico.

Science.gov (United States)

Ben Hamida, Amen; Rafful, Claudia; Jain, Sonia; Sun, Shelly; Gonzalez-Zuniga, Patricia; Rangel, Gudelia; Strathdee, Steffanie A; Werb, Dan

2018-02-01

Although most people who inject drugs (PWID) report receiving assistance during injection initiation events, little research has focused on risk factors among PWID for providing injection initiation assistance. We therefore sought to determine the influence of non-injection drug use among PWID on their risk to initiate others. We used generalized estimating equation (GEE) models on longitudinal data among a prospective cohort of PWID in Tijuana, Mexico (Proyecto El Cuete IV), while controlling for potential confounders. At baseline, 534 participants provided data on injection initiation assistance. Overall, 14% reported ever initiating others, with 4% reporting this behavior recently (i.e., in the past 6 months). In a multivariable GEE model, recent non-injection drug use was independently associated with providing injection initiation assistance (adjusted odds ratio [AOR] = 2.42, 95% confidence interval [CI] = 1.39-4.20). Further, in subanalyses examining specific drug types, recent non-injection use of cocaine (AOR = 9.31, 95% CI = 3.98-21.78), heroin (AOR = 4.00, 95% CI = 1.88-8.54), and methamphetamine (AOR = 2.03, 95% CI = 1.16-3.55) were all significantly associated with reporting providing injection initiation assistance. Our findings may have important implications for the development of interventional approaches to reduce injection initiation and related harms. Further research is needed to validate findings and inform future approaches to preventing entry into drug injecting.
The ion source development for neutral injection heating at JAERI

International Nuclear Information System (INIS)

Shirakata, H.; Itoh, T.; Kondoh, U.; Matsuda, S.; Ohara, Y.; Ohga, T.; Shibata, T.; Sugawara, T.; Tanaka, S.

1976-01-01

The neutral beam research and development effort at JAERI has been mainly concentrated on design, construction and testing of ion sources needed for present and planned heating experiments. Fundamental characteristics of the ion sources developed are described
A new dual injection system for AMS facility

International Nuclear Information System (INIS)

Liu Lin; Zhou Weijian; Cheng Peng; Yu Huagui; Chen Maobai

2007-01-01

In order to measure long-lived radioisotopes such as 10 Be with high sensitivity using an HVEE model 4130 AMS system, as well as to guarantee 14 C measurements of high precision, a new dual injection system for the AMS system is proposed. The proposal is to add a Wien filter located between the ion source system and the recombinator of the HVEE model 4130. When a pulsing voltage is optionally applied to the Wien filter, a sequential injection mode is turned on. The isotopes would alternately pass on different trajectories through the recombinator. When the pulsing voltage and magnetic field are turned off, the Wien filter acts as a field-free drift space and the standard simultaneous injection mode is on. Beam optics calculation show that the new dual injection system will increase the number of radio-nuclides which can be analyzed, keep the high precision capability for radiocarbon dating and achieve high sensitivity for 10 Be and 26 Al measurements, together with simplifying the layout as compared to existing dual-injector and dual high-energy beam line systems
Injection, injectivity and injectability in geothermal operations: problems and possible solutions. Phase I. Definition of the problems

Energy Technology Data Exchange (ETDEWEB)

Vetter, O.J.; Crichlow, H.B.

1979-02-14

The following topics are covered: thermodynamic instability of brine, injectivity loss during regular production and injection operations, injectivity loss caused by measures other than regular operations, heat mining and associated reservoir problems in reinjection, pressure maintenance through imported make-up water, suggested solutions to injection problems, and suggested solutions to injection problems: remedial and stimulation measures. (MHR)
A novel injection-locked amplitude-modulated magnetron at 1497 MHz

Energy Technology Data Exchange (ETDEWEB)

Neubauer, Michael [Muons Inc., Batavia, IL (United States); Wang, Haipeng [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)

2015-12-15

Thomas Jefferson National Accelerator Facility (JLab) uses low efficiency klystrons in the CEBAF machine. In the older portion they operate at 30% efficiency with a tube mean time between failure (MTBF) of five to six years. A highly efficient source (>55-60%) must provide a high degree of backwards compatibility, both in size and voltage requirements, to replace the klystron presently used at JLab, while providing energy savings. Muons, Inc. is developing a highly reliable, highly efficient RF source based upon a novel injection-locked amplitude modulated (AM) magnetron with a lower total cost of ownership, >80% efficiency, and MTBF of six to seven years. The design of the RF source is based upon a single injection-locked magnetron system at 8 kW capable of operating up to 13 kW, using the magnetron magnetic field to achieve the AM required for backwards compatibility to compensate for microphonics and beam loads. A novel injection-locked 1497 MHz 8 kW AM magnetron with a trim magnetic coil was designed and its operation numerically simulated during the Phase I project. The low-level RF system to control the trim field and magnetron anode voltage was designed and modeled for operation at the modulation frequencies of the microphonics. A plan for constructing a prototype magnetron and control system was developed.
Phenotype and envelope gene diversity of nef-deleted HIV-1 isolated from long-term survivors infected from a single source

Directory of Open Access Journals (Sweden)

Sullivan John S

2007-07-01

Full Text Available Abstract Background The Sydney blood bank cohort (SBBC of long-term survivors consists of multiple individuals infected with attenuated, nef-deleted variants of human immunodeficiency virus type 1 (HIV-1 acquired from a single source. Long-term prospective studies have demonstrated that the SBBC now comprises slow progressors (SP as well as long-term nonprogressors (LTNP. Convergent evolution of nef sequences in SBBC SP and LTNP indicates the in vivo pathogenicity of HIV-1 in SBBC members is dictated by factors other than nef. To better understand mechanisms underlying the pathogenicity of nef-deleted HIV-1, we examined the phenotype and env sequence diversity of sequentially isolated viruses (n = 2 from 3 SBBC members. Results The viruses characterized here were isolated from two SP spanning a three or six year period during progressive HIV-1 infection (subjects D36 and C98, respectively and from a LTNP spanning a two year period during asymptomatic, nonprogressive infection (subject C18. Both isolates from D36 were R5X4 phenotype and, compared to control HIV-1 strains, replicated to low levels in peripheral blood mononuclear cells (PBMC. In contrast, both isolates from C98 and C18 were CCR5-restricted. Both viruses isolated from C98 replicated to barely detectable levels in PBMC, whereas both viruses isolated from C18 replicated to low levels, similar to those isolated from D36. Analysis of env by V1V2 and V3 heteroduplex tracking assay, V1V2 length polymorphisms, sequencing and phylogenetic analysis showed distinct intra- and inter-patient env evolution. Conclusion Independent evolution of env despite convergent evolution of nef may contribute to the in vivo pathogenicity of nef-deleted HIV-1 in SBBC members, which may not necessarily be associated with changes in replication capacity or viral coreceptor specificity.
Groundwater monitoring for deep-well injection

International Nuclear Information System (INIS)

Chia, Y.; Chiu, J.

1994-01-01

A groundwater monitoring system for detecting waste migration would not only enhance confidence in the long-term containment of injected waste, but would also provide early warnings of contamination for prompt responses to protect underground sources of drinking water (USDWs). Field experiences in Florida have demonstrated monitoring water quality and fluid pressure changes in overlying formations is useful in detecting the upward migration of injected waste. Analytical and numerical solutions indicate changes in these two monitoring parameters can vary on the basis of hydrogeologic characteristics, operation conditions, and the distances from the injection well to the monitoring wells and to the preferential hydrologic conduits. To detect waste migration through defects around the wellbore or the leaky containment interval, groundwater monitoring wells should be placed as close as possible to an injection well. In the vertical direction, a monitoring well completed in a permeable interbed within the containment interval is expected to have the highest potential for detecting upward migration. Another acceptable horizon for groundwater monitoring is the lower portion of the buffer brine aquifer immediately above the containment interval. Monitoring wells in USDWs may be needed when waste has been detected in deeper formations or when leakage out of well casings poses a concern. A monitoring well open to the injection interval is of little value in alleviating the concerns of long-term upward migration. Moreover, the installation of the well could create additional preferential pathways. Complications in groundwater monitoring may arise at existing injection sites, especially with prior releases. It is also important to recognize that monitoring in the vicinity of the wellbore may not be effective for detecting waste migration through unidentified unplugged wells or undetected transmissive fractures
Assessing Genetic Heterogeneity within Bacterial Species Isolated from Gastrointestinal and Environmental Samples: How Many Isolates Does It Take?▿

OpenAIRE

Döpfer, D.; Buist, W.; Soyer, Y.; Munoz, M. A.; Zadoks, R. N.; Geue, L.; Engel, B.

2008-01-01

Strain typing of bacterial isolates is increasingly used to identify sources of infection or product contamination and to elucidate routes of transmission of pathogens or spoilage organisms. Usually, the number of bacterial isolates belonging to the same species that is analyzed per sample is determined by convention, convenience, laboratory capacity, or financial resources. Statistical considerations and knowledge of the heterogeneity of bacterial populations in various sources can be used t...
A Study of Spill Control Characteristics of JP-8 and Conventional Diesel Fuel with a Common Rail Direct Injection System

Directory of Open Access Journals (Sweden)

Seomoon Yang

2017-12-01

Full Text Available Diversification of energy sources is a key task for decreasing environmental impacts and global emission of gases. JP-8, a fuel derived from natural gas, coal, biomass, and waste plastics, is a bright prospect. JP-8 is considered a multi-source multi-purpose fuel, with several applications. A preliminary characterization of the JP-8 injection rate and injection quantity behavior was investigated based on the high-pressure common rail injection system used in a heavy-duty engine. According to the spill injection and injection pressure, a trade-off trend between injection rate and injection quantity was observed. As expected, pilot injection of JP-8 aviation fuel and diesel fuel affects the spray quantity and injection evolution of the subsequent operation without pilot injection. The difference in spilling between diesel and JP-8 aviation fuel is greater than the difference in injection amount per time; in the process of controlling the injector solenoid through ECU (Electric Control Units, the oil pressure valve and the needle valve operate to a higher extent in order to maintain the diesel fuel’s injection quantity volume. It was found that the total injection quantity was decreased by adding 20% pilot injection duration. Because the pilot injection quantity causes solenoid response, loss and needle lift stroke friction loss.
Isolate-specific conidiation in Trichoderma in response to different nitrogen sources.

Science.gov (United States)

Steyaert, Johanna M; Weld, Richard J; Stewart, Alison

2010-01-01

A characteristic feature of Trichoderma is the production of concentric rings of conidia in response to alternating light/dark conditions and a single ring of conidia in response to a single burst of light. In this study, conidiation was investigated in four biocontrol isolates (T. hamatum, T. atroviride, T. asperellum, T. virens) and one isolate from the mushroom pathogen species, T. pleuroticola. All five isolates produced concentric conidial rings under alternating light/dark conditions on potato-dextrose agar (PDA), however, in response to a 15min burst of blue light, only T. asperellum and T. virens produced a clearly defined conidial ring. Both T. pleuroticola and T. hamatum photoconidiated in a disk-like fashion and T. atroviride produced a broken ring with a partially filled in appearance. In the presence of primary nitrogen, T. asperellum and T. pleuroticola conidiated in a disk, whereas, when grown in the presence of secondary nitrogen, a ring of conidia was produced. Primary nitrogen promoted photoconidiation and competency to conidiate in response to light appeared dependent on the nitrogen catabolite repression state of the cell. Mycelial injury was also investigated in the same five isolates of Trichoderma on PDA and under different nitrogen statuses. For the first time, we report that conidiation in response to injury is differentially regulated in different isolates/species of Trichoderma. Copyright © 2009 The British Mycological Society. Published by Elsevier Ltd. All rights reserved.
Recovery of a Burkholderia thailandensis-like isolate from an Australian water source

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Wilkins Patricia P

2008-04-01

Full Text Available Abstract Background Burkholderia thailandensis, a close relative of Burkholderia pseudomallei, has previously been reported only from Southeast Asia and North America. It is biochemically differentiated from B. pseudomallei by the ability to utilize arabinose. During the course of environmental sampling for B. pseudomallei in the Northern Territory of Australia, an isolate, MSMB 43, was recovered that is arabinose positive. Results Genetic analysis using 16S rDNA sequencing and DNA/DNA hybridization indicates that MSMB 43 is most similar to B. thailandensis although multi-locus sequence typing indicates that this isolate is divergent from both B. pseudomallei and other described B. thailandensis. Conclusion We report the isolation and initial characterization of strain MSMB 43, which is a B. thailandensis-like isolate recovered in Australia.
Balloon-occluded retrograde transvenous obliteration versus endoscopic injection sclerotherapy for isolated gastric varices: a comparative study.

Science.gov (United States)

Emori, Keigo; Toyonaga, Atsushi; Oho, Kazuhiko; Kumamoto, Masafumi; Haruta, Tsuyoshi; Inoue, Hiroto; Morita, Yukihiko; Mitsuyama, Keiichi; Tsuruta, Osamu; Sata, Michio

2014-01-01

Isolated gastric varices (IGV) have a lower risk of bleeding than esophageal varices, however IGV bleeding is associated with a higher mortality than bleeding of esophageal varices. In recent years, two widely used treatments for IGV have been balloon-occluded retrograde transvenous obliteration (B-RTO) and endoscopic injection sclerotherapy (EIS) using cyanoacrylate or ethanolamine oleate (EO). This study compared these two treatment methods for IGV. The subjects were 112 patients who were treated at our hospital for IGV bleeding between October 1990 and December 2003. Forty-nine (49) patients were treated with B-RTO and 63 patients with EIS. These two patient groups were compared as regards content of treatment, post-treatment incidence of variceal bleeding, incidence of IGV rebleeding, survival rate, cause of death, and complications. Multivariate analysis was performed on post-treatment variceal bleeding and survival. Although EO was used in higher amounts in the B-RTO group than in the EIS group, the B-RTO group had a significantly lower number of treatment sessions and a significantly shorter treatment period (pIGV rebleeding after treatment than the B-RTO group. Treatment method was the only independent prognostic factor of IGV bleeding after treatment (p=0.024). The two groups did not differ significantly in the percentage of patients with aggravated esophageal varices after treatment. Bleeding from ectopic varices was not observed in any patient. There was no significant difference in survival by treatment method. The presence of hepatocellular carcinoma was the only independent prognostic factor for survival (p=0.003). It is concluded that B-RTO was more effective than EIS in the eradication of IGV and prevention of IGV recurrence and rebleeding.

COLLECTIVE EFFECTS AT INJECTION FOR THE APS-U MBA LATTICE

Energy Technology Data Exchange (ETDEWEB)

Lindberg, R.; Borland, M.; Blednykh, A.

2017-06-25

The Advanced Photon Source has proposed an upgrade to a multi-bend achromat (MBA) with a proposed timing mode calls for 48 bunches of 15 nC each. In this mode of operation we find that phase space mismatch from the booster can drive large wakefields that in turn may limit the current below that of the nominal collective instability threshold. We show that collective effects at injection lead to emittance growth that makes usual off-axis accumulation very challenging. On-axis injection ameliorates many of these issues, but we find that transverse feedback is still required. We explore the role of impedance, feedback, and phase-space mismatch on transverse instabilities at injection.
Experimental arthritis induced by a clinical Mycoplasma fermentans isolate

Directory of Open Access Journals (Sweden)

Giono Silvia

2002-06-01

Full Text Available Abstract Background Mycoplasma fermentans has been associated with rheumatoid arthritis. Recently, it was detected in the joints and blood of patients with rheumatoid arthritis, but it is not clear yet how the bacteria enter the body and reach the joints. The purpose of this study was to determine the ability of M. fermentans to induce experimental arthritis in rabbits following inoculation of the bacteria in the trachea and knee joints. Methods P-140 and PG-18 strains were each injected in the knee joints of 14 rabbits in order to evaluate and compare their arthritogenicity. P-140 was also injected in the trachea of 14 rabbits in order to test the ability of the bacteria to reach the joints and induce arthritis. Results M. fermentans produced an acute arthritis in rabbits. Joint swelling appeared first in rabbits injected with P-140, which caused a more severe arthritis than PG-18. Both strains were able to migrate to the uninoculated knee joints and they were detected viable in the joints all along the duration of the experiment. Changes in the synovial tissue were more severe by the end of the experiment and characterized by the infiltration of neutrophils and substitution of adipose tissue by connective tissue. Rabbits intracheally injected with P-140 showed induced arthritis and the bacteria could be isolated from lungs, blood, heart, kidney, spleen, brain and joints. Conclusion M. fermentans induced arthritis regardless of the inoculation route. These findings may help explain why mycoplasmas are commonly isolated from the joints of rheumatic patients.
Fatal injection: a survey of modern code injection attack countermeasures

Directory of Open Access Journals (Sweden)

Dimitris Mitropoulos

2017-11-01

Full Text Available With a code injection attack (CIA an attacker can introduce malicious code into a computer program or system that fails to properly encode data that comes from an untrusted source. A CIA can have different forms depending on the execution context of the application and the location of the programming flaw that leads to the attack. Currently, CIAs are considered one of the most damaging classes of application attacks since they can severely affect an organisation’s infrastructure and cause financial and reputational damage to it. In this paper we examine and categorize the countermeasures developed to detect the various attack forms. In particular, we identify two distinct categories. The first incorporates static program analysis tools used to eliminate flaws that can lead to such attacks during the development of the system. The second involves the use of dynamic detection safeguards that prevent code injection attacks while the system is in production mode. Our analysis is based on nonfunctional characteristics that are considered critical when creating security mechanisms. Such characteristics involve usability, overhead, implementation dependencies, false positives and false negatives. Our categorization and analysis can help both researchers and practitioners either to develop novel approaches, or use the appropriate mechanisms according to their needs.
Wire rope isolators for vibration isolation of equipment and structures – A review

International Nuclear Information System (INIS)

Balaji, P S; Rahman, M E; Lau, H H; Moussa, Leblouba

2015-01-01

Vibrations and shocks are studied using various techniques and analyzed to predict their detrimental effect on the equipment and structures. In cases, where the effects of vibration become unacceptable, it may cause structural damage and affect the operation of the equipment. Hence, adding a discrete system to isolate the vibration from source becomes necessary. The Wire Rope Isolator (WRI) can be used to effectively isolate the system from disturbing vibrations. The WRI is a type of passive isolator that exhibits nonlinear behavior. It consists of stranded wire rope held between two metal retainer bars and the metal wire rope is made up of individual wire strands that are in frictional contact with each other, hence, it is a kind of friction-type isolator. This paper compiles the research work on wire rope isolators. This paper presents the research work under two categories, namely monotonic and cyclic loading behaviors of WRI. The review also discusses the different terminologies associated with vibration isolation system and highlights the comparison between various isolation systems. (paper)
Testosterone Injection

Science.gov (United States)

... typical male characteristics. Testosterone injection works by supplying synthetic testosterone to replace the testosterone that is normally ... as a pellet to be injected under the skin.Testosterone injection may control your symptoms but will ...
GANIL Workshop on Ion Sources

International Nuclear Information System (INIS)

Leroy, Renan

1999-01-01

The proceedings of the GANIL Workshop on Ion Sources held at GANIL - Caen on 18-19 March 1999 contains 13 papers aiming at improving the old source operation and developing new types of sources for nuclear research and studies of ion physics. A number of reports are devoted to applications like surface treatment, ion implantation or fusion injection. The 1+→n+ transformation, charged particle transport in ECR sources, addition of cesium and xenon in negative ion sources and other basic issues in ion sources are also addressed
Intense negative hydrogen ion source for neutral injection into tokamaks

International Nuclear Information System (INIS)

Prelec, K.; Sluyters, T.

1975-01-01

In this scheme negative ions are extracted from a plasma source, accelerated to the required energy and then neutralized by stripping in a gas, metal vapor or plasma jet. One of the most promising direct extraction sources is the magnetron source, operating in the mixed hydrogen-cesium mode. In the present source cathode current densities are up to 20 A/cm 2 at arc voltages between 100 V and 150 V. In order to utilize the discharge more efficiently multislit extraction geometry was adopted. Highest currents were obtained by using six slits, with a total extraction area of 1.35 cm 2 . At an extraction voltage of 18 kV negative hydrogen ion currents close to 1 A were obtained, which corresponds to current densities of about 0.7 A/cm 2 at the extraction aperture. Pulse length was 10-20 ms and the repetition rate 0.1 Hz. The total extracted current was usually 2-3 times the H - current
Cluster Observations of Particle Injections in the Exterior Cusp

Science.gov (United States)

Escoubet, C. P.; Grison, B.; Berchem, J.; Trattner, K. J.; Lavraud, B.; Pitout, F.; Soucek, J.; Richard, R. L.; Laakso, H. E.; Masson, A.; Dunlop, M. W.; Dandouras, I. S.; Reme, H.; Fazakerley, A. N.; Daly, P. W.

2014-12-01

The main process that injects solar wind plasma into the polar cusp is now generally accepted to be magnetic reconnection. Depending on the IMF direction, this process takes place equatorward (for IMF southward), poleward (for IMF northward) or on the dusk or dawn sides (for IMF azimuthal) of the cusp. We report a Cluster crossing on 5 January 2002 near the exterior cusp on the southern dusk side. The IMF was mainly azimuthal (IMF-By around -5 nT), the solar wind speed lower than usual around 280 km/s with the density of order 5 cm-3. The four Cluster spacecraft had an elongated configuration near the magnetopause. C4 was the first spacecraft to enter the cusp around 19:52:04 UT, followed by C2 at 19:52:35 UT, C1 at 19:54:24 UT and C3 at 20:13:15 UT. C4 and C1 observed two ion energy dispersions at 20:10 UT and 20:40 UT and C3 at 20:35 UT and 21:15 UT. Using the time of flight technique on the upgoing and downgoing ions, which leads to energy dispersions, we obtain distances of the ion sources between 14 and 20 RE from the spacecraft. Using Tsyganenko model, we find that these sources are located on the dusk flank, past the terminator. The first injection by C3 is seen at approximately the same time as the 2nd injection on C1 but their sources at the magnetopause were separated by more than 7 RE. This would imply that two distinct sources were active at the same time on the dusk flank of the magnetosphere. In addition, a flow reversal was observed at the magnetopause on C4 which would be an indication that reconnection is taking place near the exterior cusp.
Investigating Salmonella Eko from Various Sources in Nigeria by Whole Genome Sequencing to Identify the Source of Human Infections

DEFF Research Database (Denmark)

Leekitcharoenphon, Pimlapas; Raufu, Ibrahim; Thorup Nielsen, Mette

2016-01-01

Twenty-six Salmonella enterica serovar Eko isolated from various sources in Nigeria were investigated by whole genome sequencing to identify the source of human infections. Diversity among the isolates was observed and camel and cattle were identified as the primary reservoirs and the most likely...
Large scale injection test (LASGIT) modelling

International Nuclear Information System (INIS)

Arnedo, D.; Olivella, S.; Alonso, E.E.

2010-01-01

. In addition the horizontal interfaces between the bentonite blocks and the vertical interfaces corresponding to the host rock and the canister walls contacts are considered different materials but the properties are similar to the ones in the bentonite. Actually, this is done because interfaces are believed to be a potential preferential path for gas migration through the buffer. The host rock and the canister are not included in the model due to its high stiffness with respect to bentonite. A constitutive model that considers non-linear elasticity and visco-plasticity based on BBM model is adopted for the bentonite and the interfaces. An embedded fracture permeability model in which permeability and retention curve depend on strains through a fracture aperture is considered in the hydraulic problem. The following stages of the experiment are simulated: - Construction of the isolation barrier inside the deposition hole, - Hydration stage 1 in which the liquid pressure is increased at the Filter Mats and de canister Injection Filters up to 1.5 MPa in an initial stage and up to 2.35 MPa in a second stage in order to saturate the buffer, - Hydraulic test 1, - Gas injection test 1. The simulation results will be compared to the experimental record of different variables: total stresses and liquid pressure at the rock wall, at the canister wall, and at some points within the bentonite buffer. It will be interesting to try to explain if preferential paths develop and where. This is controlled by the swelling capacity of the buffer and its ability to seal the interfaces initially not closed between the clay and the wall and between the blocks. (authors)
Drug use and AIDS: estimating injection prevalence in a rural state.

Science.gov (United States)

Leukefeld, Carl G; Logan, T K; Farabee, David; Clayton, Richard

2002-01-01

This paper presents approaches used in one rural U.S. state to describe the level of injecting drug use and to estimate the number of injectors not receiving drug-user treatment. The focus is on two broad areas of estimation that were used to present the prevalence of injecting drug use in Kentucky. The first estimation approach uses available data from secondary data sources. The second approach involves three small community studies.
Isolation and Genotyping of Acanthamoeba Strains from Environmental Sources in Ahvaz City, Khuzestan Province, Southern Iran

Science.gov (United States)

Rahdar, M; Niyyati, M; Salehi, M; Feghhi, M; Makvandi, M; Pourmehdi, M; Farnia, S

2012-01-01

Background Acanthamoeba spp. are free-living amoebae commonly found in the environmental sources such as water, soil, and air. This ubiquitous amoeba is the causative agent of amoebic keratitis (AK). The objective of the present study was to investigate the presence of Acanthamoeba spp. in water and soil sources in Ahvaz City, Khuzestan Province, southern Iran. Methods In general, 110 samples of water and soil were taken from different localities of Ahvaz including agricultural canals, rivers, and swimming pools. Filtration and cultivation were carried out on non-nutrient agar medium (NNA). Axenic cultivation was performed for all of positive isolates. PCR analysis was conducted on positive samples. Sequencing was done for 15 PCR products. Genotypes were identified by Blast search and homology analysis. Results Acanthamoeba spp. was found in 43 (71.6%) of samples of water and 13 (26%) soil samples. Genotyping of 15 samples proved that Acanthamoeba belonged to T4 (86.6%), T2 (6.6%), and T5 (6.6%) genotypes. Conclusion TYI-S-33 medium could be better than PYG medium for Acanthamoeba axenic culture. PMID:23323088
Low levels of persistent organic pollutants (POPs) in New Zealand eels reflect isolation from atmospheric sources

International Nuclear Information System (INIS)

Holmqvist, Niklas; Stenroth, Patrik; Berglund, Olof; Nystroem, Per; Olsson, Karin; Jellyman, Don; McIntosh, Angus R.; Larsson, Per

2006-01-01

Polychlorinated biphenyls (PCBs) and organic pesticides (i.e., DDTs) were measured in long finned eels (Anguilla dieffenbachii) in 17 streams on the west coast of South Island, New Zealand. Very low levels of PCBs and low levels of ppDDE were found. The concentrations of PCBs and ppDDE were not correlated within sites indicating that different processes determined the levels of the two pollutants in New Zealand eels. The PCBs probably originate from atmospheric transport, ppDDE levels are determined by land use and are higher in agriculture areas. The low contamination level of these aquatic systems seems to be a function of a low input from both long and short-range transport as well as few local point sources. No correlation could be found between lipid content and persistent organic pollutants (POPs) concentration (as shown in previous studies) in the eels which could be explained by low and irregular intake of the pollutants. - Low levels of PCBs found in New Zealand eels reflect isolation from atmospheric sources while DDTs levels are determined by land use
Vaccines Meet Big Data: State-of-the-Art and Future Prospects. From the Classical 3Is ("Isolate-Inactivate-Inject") Vaccinology 1.0 to Vaccinology 3.0, Vaccinomics, and Beyond: A Historical Overview.

Science.gov (United States)

Bragazzi, Nicola Luigi; Gianfredi, Vincenza; Villarini, Milena; Rosselli, Roberto; Nasr, Ahmed; Hussein, Amr; Martini, Mariano; Behzadifar, Masoud

2018-01-01

Vaccines are public health interventions aimed at preventing infections-related mortality, morbidity, and disability. While vaccines have been successfully designed for those infectious diseases preventable by preexisting neutralizing specific antibodies, for other communicable diseases, additional immunological mechanisms should be elicited to achieve a full protection. "New vaccines" are particularly urgent in the nowadays society, in which economic growth, globalization, and immigration are leading to the emergence/reemergence of old and new infectious agents at the animal-human interface. Conventional vaccinology (the so-called "vaccinology 1.0") was officially born in 1796 thanks to the contribution of Edward Jenner. Entering the twenty-first century, vaccinology has shifted from a classical discipline in which serendipity and the Pasteurian principle of the three I s (isolate, inactivate, and inject) played a major role to a science, characterized by a rational design and plan ("vaccinology 3.0"). This shift has been possible thanks to Big Data, characterized by different dimensions, such as high volume, velocity, and variety of data. Big Data sources include new cutting-edge, high-throughput technologies, electronic registries, social media, and social networks, among others. The current mini-review aims at exploring the potential roles as well as pitfalls and challenges of Big Data in shaping the future vaccinology, moving toward a tailored and personalized vaccine design and administration.
Study of axial injection of polarized protons into the grenoble cyclotron; Contribution a l'etude de l'injection axiale pour protons polarises sur le cyclotron de Grenoble

Energy Technology Data Exchange (ETDEWEB)

Pabot, J [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

1969-07-01

By injecting ions axially into a cyclotron, it is possible to accelerate particles (polarized particles, heavy ions, etc...) obtainable only with difficulty when an internal ion source is used. In this work, after justifying the choice of an axial injection device equipped with a 'pseudo-cylindrical' deflector for the Grenoble cyclotron, we study theoretically the principle of such a detector, the choice of its parameters, and the effect of this choice on the conditions of acceleration of the beam by the cyclotron. From the experimental point of view, this report describes two operations which made it possible to check that the chosen injection device operated satisfactorily, qualitatively initially (electron model), then quantitatively (proton model). In conclusion, we believe that the Grenoble cyclotron thus equipped will be able to provide a relatively dense beam of polarized protons. (author) [French] L'injection axiale d'ions dans un cyclotron permet d'accelerer des particules (particules polarisees, ions lourds... ) difficiles a obtenir avec une source interne d'ions. Dans ce travail, apres avoir justifie le choix d'un dispositif d'injection axiale equipe d'un deflecteur 'pseudo-cylindrique' pour le cyclotron de Grenoble, nous avons etudie, du point de vue theorique, le principe d'un tel deflecteur, le choix de ses parametres, et l'incidence de ce choix sur les conditions d'acceleration du faisceau par le cyclotron. Du point de vue experimental, ce rapport decrit deux manipulations qui ont permis de verifier le bon fonctionnement du dispositif d'injection retenu, qualitativement d'abord (modele a electrons), quantitativement ensuite (maquette a protons). En conclusion, nous estimons que le cyclotron de Grenoble ainsi equipe, peut fournir un faisceau relativement intense de protons polarises. (auteur)
Dynamical injections as the source of near geostationary quiet time particle spatial boundaries

International Nuclear Information System (INIS)

Mauk, B.H.; Meng, C.I.

1983-01-01

To test our understanding of quasi-stationary magnetospheric particle convection, we address here a particular class of particle feature (plasma dropouts at 0 eV to 5 keV) observed regularly by near geostationary satellites in the noon to dusk quadrant, often during the apparent absence of recent (hours) substorm activity. At first consideration the feature appears to result from the passage of the satellites toward and into the so-called ''forbidden zones'' of the quasi-stationary particle convection patterns. It is demonstrated here that the energy dispersion of the feature cannot be explained by simple stationary convection models even when loss processes are imposed on those particles that penetrate most closely to the earth. Also, the radial position of the feature does not vary with geomagnetic activity as expected from steady convection models. It is concluded that dynamical processes are responsible. However, models based on the modification of the so-called cross-tail field configuration against initial stationary convection patterns are rejected here because these models preserve the qualitative sense of the energy dispersions of the initial patterns. It is proposed that the spatial structures of pase (24 hours) dynamical, nightside particle injections determine to a great extent the character of the feature. It is shown that detailed simulations based on the double-spiraled ''injection boundary'' concept (used previously to reproduce the fast changing nighttime features) reproduce very well the character and dispersion senses of the noon-to-dusk feature by allowing the distributions to evolve for many hours. It is emphasized that the portion of the original injection boundary which gives rise to this feature of interest is the decidely ''non-Alfvenic'' portion
Brighter H- source for the intense pulsed neutron source accelerator system

International Nuclear Information System (INIS)

Stipp, V.; DeWitt, A.; Madsen, J.

1983-01-01

Further increases in the beam intensity of the Intense Pulsed Neutron Source (IPNS) at Argonne National Laboratory required the replacement of the H - source with a higher current source. A magnetron ion source of Fermi National Accelerator Laboratory (FNAL) design was adapted with a grooved cathode to provide a stable 40 to 50 mA of beam operating at 30 Hz for up to a 90 μs pulse duration. Problems of space charge blowup due to the lack of neutralization of the H - beam were solved by injecting additional gs into the 20 keV transport system. The source has recently been installed in the machine and the available input to the accelerator has more than doubled
Role of passive valves & devices in poison injection system of advanced heavy water reactor

International Nuclear Information System (INIS)

Sapra, M.K.; Kundu, S.; Vijayan, P.K.; Vaze, K.K.; Sinha, R.K.

2014-01-01

The Advanced Heavy Water Reactor (AHWR) is a 300 MWe pressure tube type boiling light water (H 2 O) cooled, heavy water (D 2 O) moderated reactor. The reactor design is based on well-proven water reactor technologies and incorporates a number of passive safety features such as natural circulation core cooling; direct in-bundle injection of light water coolant during a Loss of Coolant Accident (LOCA) from Advanced Accumulators and Gravity Driven Water Pool by passive means; Passive Decay Heat Removal using Isolation Condensers, Passive Containment Cooling System and Passive Containment Isolation System. In addition to above, there is another passive safety system named as Passive Poison Injection System (PPIS) which is capable of shutting down the reactor for a prolonged time. It is an additional safety system in AHWR to fulfill the shutdown function in the event of failure of wired shutdown systems i.e. primary and secondary shut down systems of the reactor. When demanded, PPIS injects the liquid poison into the moderator by passive means using passive valves and devices. On increase of main heat transport (MHT) system pressure beyond a predetermined value, a set of rupture disks burst, which in-turn actuate the passive valve. The opening of passive valve initiates inrush of high pressure helium gas into poison tanks to push the poison into the moderator system, thereby shutting down the reactor. This paper primarily deals with design and development of Passive Poison Injection System (PPIS) and its passive valves & devices. Recently, a prototype DN 65 size Poison Injection Passive Valve (PIPV) has been developed for AHWR usage and tested rigorously under simulated conditions. The paper will highlight the role of passive valves & devices in PPIS of AHWR. The design concept and test results of passive valves along with rupture disk performance will also be covered. (author)
Development of the High Current Ion Source for Neutral Beam Injection

Energy Technology Data Exchange (ETDEWEB)

Lee, Hun Ju; Kim, S. H.; Jang, D. H. [Jae Ju University, Jaeju (Korea, Republic of)

1997-08-01

The scope of the 1st year research is to design an 140keV deuterium ion source which has a beam current of 30-40A. According to the collected data, the model of an ion source for NBI of KSTAR was established. The negative ion source, which has good neutralization effecting in high energy, was selected. To generate a plasma, the thoriated tungsten filament was adopted. To increase the efficiency of plasma, the multi cusp type magnetic field was attached. The magnetic field was calculated by POISSON code. The extraction structure was designed with EGUN code, to extract the high quality ion beam. The design of a high current ion source for NBI was carried out. To develop the high current ion source with the high operational stability and the long lifetime, the parameters including an arc current, gas pressure and extraction voltage should be optimized. If designed ion source would be fabricated, its parameters could be optimized experimentally. Through the optimization of the ion source parameter, the core technology for NBI is established and the experiment of current drive in the fusion device can be performed. This technology also can be applied to the synthesis of new material and semiconductor industry. 18 refs., 11 tabs., 19 figs. (author)
Amino Acid Composition of an Organic Brown Rice Protein Concentrate and Isolate Compared to Soy and Whey Concentrates and Isolates.

Science.gov (United States)

Kalman, Douglas S

2014-06-30

A protein concentrate (Oryzatein-80™) and a protein isolate (Oryzatein-90™) from organic whole-grain brown rice were analyzed for their amino acid composition. Two samples from different batches of Oryzatein-90™ and one sample of Oryzatein-80™ were provided by Axiom Foods (Los Angeles, CA, USA). Preparation and analysis was carried out by Covance Laboratories (Madison, WI, USA). After hydrolysis in 6-N hydrochloric acid for 24 h at approximately 110 °C and further chemical stabilization, samples were analyzed by HPLC after pre-injection derivitization. Total amino acid content of both the isolate and the concentrate was approximately 78% by weight with 36% essential amino acids and 18% branched-chain amino acids. These results are similar to the profiles of raw and cooked brown rice except in the case of glutamic acid which was 3% lower in the isolate and concentrate. The amino acid content and profile of the Oryzatein-90™ isolate was similar to published values for soy protein isolate but the total, essential, and branched-chain amino acid content of whey protein isolate was 20%, 39% and 33% greater, respectively, than that of Oryzatein-90™. These results provide a valuable addition to the nutrient database of protein isolates and concentrates from cereal grains.

VIBRATION ISOLATION SYSTEM PROBABILITY ANALYSIS

Directory of Open Access Journals (Sweden)

Smirnov Vladimir Alexandrovich

2012-10-01

Full Text Available The article deals with the probability analysis for a vibration isolation system of high-precision equipment, which is extremely sensitive to low-frequency oscillations even of submicron amplitude. The external sources of low-frequency vibrations may include the natural city background or internal low-frequency sources inside buildings (pedestrian activity, HVAC. Taking Gauss distribution into account, the author estimates the probability of the relative displacement of the isolated mass being still lower than the vibration criteria. This problem is being solved in the three dimensional space, evolved by the system parameters, including damping and natural frequency. According to this probability distribution, the chance of exceeding the vibration criteria for a vibration isolation system is evaluated. Optimal system parameters - damping and natural frequency - are being developed, thus the possibility of exceeding vibration criteria VC-E and VC-D is assumed to be less than 0.04.
Isolation and Identification of Pyrene Mineralizing Mycobacterium spp. from Contaminated and Uncontaminated Sources

International Nuclear Information System (INIS)

Lease, C.W.M; Bentham, R.H; Gaskin, S.E; Juhasz, A.L

2011-01-01

Mycobacterium isolates obtained from PAH-contaminated and uncontaminated matrices were evaluated for their ability to degrade three-, four- and five-ring PAHs. PAH enrichment studies were prepared using pyrene and inocula obtained from manufacturing gas plant (MGP) soil, uncontaminated agricultural soil, and faeces from Macropus fuliginosus (Western Grey Kangaroo). Three pyrene-degrading microorganisms isolated from the corresponding enrichment cultures had broad substrate ranges, however, isolates could be differentiated based on surfactant, phenol, hydrocarbon and PAH utilisation. 16S rRNA analysis identified all three isolates as Mycobacterium sp. The Mycobacterium spp. could rapidly degrade phenanthrene and pyrene, however, no strain had the capacity to utilise fluorene or benzo[a]pyrene. When pyrene mineralisation experiments were performed, 70-79% of added 14 C was evolved as 14 CO 2 after 10 days. The present study demonstrates that PAH degrading microorganisms may be isolated from a diverse range of environmental matrices. The present study demonstrates that prior exposure to PAHs was not a prerequisite for PAH catabolic activity for two of these Mycobacterium isolates.
Isolation of saprophytic Leptospira spp. from a selected environmental water source of Argentina.

Science.gov (United States)

Scialfa, Exequiel; Grune, Sylvia; Brihuega, Bibiana; Aguirre, Pablo; Rivero, Marina

2017-11-29

Ten Leptospira spp. strains were isolated from water samples from Nievas stream, Olavarría, Buenos Aires province (Argentina). The isolates showed the typical motility and morphology of the genus Leptospira under dark field microscopy, developing in liquid EMJH medium after eight days of incubation at 13°C and 30°C. All isolates were negative by the Multiple Locus Variable Number Tandem Repeat Analysis (MLVA). Molecular identification by 16S rRNA gene sequencing identified all isolates as nonpathogenic leptospires. Four isolates showed a genetic profile identical to that of the reference strain Leptospira biflexa serovar Patoc, and six isolates revealed sequence similarities within the 97-98% range, closely related to Leptospira yanagawae and Leptospira meyeri, respectively. Strains ScialfaASA42, ScialfaASA45, ScialfaASA44, ScialfaASA47, ScialfaASA49, ScialfaASA50 and ScialfaASA51 possibly represent a novel species of the genus Leptospira. Copyright © 2017 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.
Computational study of the effect of different injection angle on heavy duty diesel engine combustion

Directory of Open Access Journals (Sweden)

Ranjbar Ali Akbar

2009-01-01

Full Text Available Diesel engines exhausting gaseous emission and particulate matter have long been regarded as one of the major air pollution sources, particularly in metropolitan areas, and have been a source of serious public concern for a long time. The choosing various injection strategies is not only motivated by cost reduction but is also one of the potentially effective techniques to reduce exhaust emission from diesel engines. The purpose of this study is to investigate the effect of different injection angles on a heavy duty diesel engine and emission characteristics. The varieties of injection angle were simulated and the emissions like soot and NO is calculated. The comparison between the different injection strategies was also investigated. A combustion chamber for three injection strategies (injection direction with angles of α=67.5, 70, and 72.5 degree was simulated. The comparative study involving rate of heat release, in-cylinder temperature, in-cylinder pressure, NO and soot emissions were also reported for different injection strategies. The case of α=70 is optimum because in this manner the emissions are lower in almost most of crank angle than two other cases and the in-cylinder pressure, which is a representation of engine power, is higher than in the case of α=67.5 and just a little lower than in the case of α=72.5.
Water sources as reservoirs of Vibrio cholerae O1 and non-O1 strains in Bepanda, Douala (Cameroon): relationship between isolation and physico-chemical factors.

Science.gov (United States)

Akoachere, Jane-Francis Tatah Kihla; Mbuntcha, Christelle Kwedjeu Pulcherie

2014-07-30

Cholera has been endemic in Douala since 1971. Most outbreaks start from Bepanda, an overcrowded neighbourhood with poor hygiene and sanitary conditions. We investigated water sources in Bepanda as reservoirs of Vibrio cholerae, the causative agent of cholera, determined its antibiotic susceptibility and some physico-chemical characteristics that could maintain the endemicity of this organism in Bepanda. Three hundred and eighteen water samples collected from 45 wells, 8 taps and 1 stream from February to July 2009 were analyzed for V. cholerae using standard methods. Isolates were characterized morphologically, biochemically and serologically. The disc diffusion technique was employed to investigate antibiotic susceptibility. Differences in prevalence of organism between seasons were analysed. Correlation strength and direction of association between physico-chemical parameters and occurrence of V. cholerae was analyzed using the Kendall tau_b non-parametric correlation. This was further confirmed with the forward-stepwise binary logistic regression. Eighty-seven (27.4%) samples were positive for V. cholerae. Isolation was highest from wells. The organism was isolated in the rainy season and dry season but the frequency of isolation was significantly higher (χ2 = 7.009, df = 1, P = 0.008) in the rainy season. Of the 96 confirmed V. cholerae isolates, 32 (33.3%) belonged to serogroup O1 and 64 (66.6%) were serogroup non-O1/non-O139. Isolates from tap (municipal water) were non-O1/non-O139 strains. Salinity had a significant positive correlation with isolation in the dry season (+0.267, P = 0.015) and rainy season (+0.223, P = 0.028). The forward-stepwise method of binary logistic regression indicated that as pH (Wald = 11.753, df = 1), P = 0.001) increased, odds of isolation of V. cholerae also increased (B = 1.297, S.E = 0.378, Exp(B) = 3.657). All isolates were sensitive to ciprofloxacin and ofloxacin. Multi-drug resistance was predominant among the non-O1/non
The role of preventive topical antibiotic treatment prior to intravitreal injection

Directory of Open Access Journals (Sweden)

Elena Vladimirovna Ageeva

2015-06-01

Full Text Available Treatment of wet age-related macular degeneration (AMD requires frequent intravitreal injections of anti-VEGF agents, sometimes on monthly basis during a long period of time. Endophthalmitis is a rare but extremely severe complication of intravitreal injections. As it has been proven before, the flora from the conjunctival surface is the main source for endophthalmitis. Using Povidone-iodine solution (Betadine10 % Povidone-iodine, EGIS PHARMACEUTICALS is the only way to prevent endophthalmitis. The efficacy of it was proven by numerous studies. No evidence exists that topical antibiotiotics prior and after injections could be effective for prevention of endophthalmitis. Purpose: To study the advisability of topical antibiotic application before intravitreal injection. Materials and methods: Under investigation, there were 25 eyes of 25 patients with wet AMD treated by anti-VEGF intravitreal injections. All patients used topical antibiotics 3 days before injection. Conjunctival culture from injection eye was collected three times: before topical antibiotic use; after topical antibiotic use, and after Betadine 5 % application. Results: The rates of Staphylococcus epidermidis before and after topical antibiotic use were approximately equal. However there was no Staphylococcus epidermidis found after Betadine 5 % application. Conclusion: Our study showed the effectiveness of Betadine 5 % solution in conjunctival flora reduction. Use of topical antibiotics 3 days prior intravitreal injections is not effective. Key words: age-related macular degeneration; endophthalmitis; intravitreal injection; topical antibiotics; endophthalmitis prevention.
Attack Detection/Isolation via a Secure Multisensor Fusion Framework for Cyberphysical Systems

Directory of Open Access Journals (Sweden)

Arash Mohammadi

2018-01-01

Full Text Available Motivated by rapid growth of cyberphysical systems (CPSs and the necessity to provide secure state estimates against potential data injection attacks in their application domains, the paper proposes a secure and innovative attack detection and isolation fusion framework. The proposed multisensor fusion framework provides secure state estimates by using ideas from interactive multiple models (IMM combined with a novel fuzzy-based attack detection/isolation mechanism. The IMM filter is used to adjust the system’s uncertainty adaptively via model probabilities by using a hybrid state model consisting of two behaviour modes, one corresponding to the ideal scenario and one associated with the attack behaviour mode. The state chi-square test is then incorporated through the proposed fuzzy-based fusion framework to detect and isolate potential data injection attacks. In other words, the validation probability of each sensor is calculated based on the value of the chi-square test. Finally, by incorporation of the validation probability of each sensor, the weights of its associated subsystem are computed. To be concrete, an integrated navigation system is simulated with three types of attacks ranging from a constant bias attack to a non-Gaussian stochastic attack to evaluate the proposed attack detection and isolation fusion framework.
A control-oriented approach to estimate the injected fuel mass on the basis of the measured in-cylinder pressure in multiple injection diesel engines

International Nuclear Information System (INIS)

Finesso, Roberto; Spessa, Ezio

2015-01-01

Highlights: • Control-oriented method to estimate injected quantities from in-cylinder pressure. • Able to calculate the injected quantities for multiple injection strategies. • Based on the inversion of a heat-release predictive model. • Low computational time demanding. - Abstract: A new control-oriented methodology has been developed to estimate the injected fuel quantities, in real-time, in multiple injection DI diesel engines on the basis of the measured in-cylinder pressure. The method is based on the inversion of a predictive combustion model that was previously developed by the authors, and that is capable of estimating the heat release rate and the in-cylinder pressure on the basis of the injection rate. The model equations have been rewritten in order to derive the injected mass as an output quantity, starting from use of the measured in-cylinder pressure as input. It has been verified that the proposed method is capable of estimating the injected mass of pilot pulses with an uncertainty of the order of ±0.15 mg/cyc, and the total injected mass with an uncertainty of the order of ±0.9 mg/cyc. The main sources of uncertainty are related to the estimation of the in-cylinder heat transfer and of the isentropic coefficient γ = c_p/c_v. The estimation of the actual injected quantities in the combustion chamber can represent a powerful means to diagnose the behavior of the injectors during engine operation, and offers the possibility of monitoring effects, such as injector ageing and injector coking, as well as of allowing an accurate control of the pilot injected quantities to be obtained; the latter are in fact usually characterized by a large dispersion, with negative consequences on the combustion quality and emission formation. The approach is characterized by a very low computational time, and is therefore suitable for control-oriented applications.
Safe injection procedures, injection practices, and needlestick ...

African Journals Online (AJOL)

Nermine Mohamed Tawfik Foda

2017-01-10

Jan 10, 2017 ... sures regarding disposable injection equipment, waste containers, hand hygiene ... injection practices lead to high prevalence of NSSIs in operating rooms. .... guidelines, the availability of training courses to HCWs, and provi-.
Injection-depth-locking axial motion guided handheld micro-injector using CP-SSOCT.

Science.gov (United States)

Cheon, Gyeong Woo; Huang, Yong; Kwag, Hye Rin; Kim, Ki-Young; Taylor, Russell H; Gehlbach, Peter L; Kang, Jin U

2014-01-01

This paper presents a handheld micro-injector system using common-path swept source optical coherence tomography (CP-SSOCT) as a distal sensor with highly accurate injection-depth-locking. To achieve real-time, highly precise, and intuitive freehand control, the system used graphics processing unit (GPU) to process the oversampled OCT signal with high throughput and a smart customized motion monitoring control algorithm. A performance evaluation was conducted with 60-insertions and fluorescein dye injection tests to show how accurately the system can guide the needle and lock to the target depth. The evaluation tests show our system can guide the injection needle into the desired depth with 4.12 um average deviation error while injecting 50 nl of fluorescein dye.
First observations of acceleration of injected electrons in a laser plasma beatwave experiment

International Nuclear Information System (INIS)

Ebrahim, N.A.; Martin, F.; Bordeur, P.; Heighway, E.A.; Matte, J.P.; Pepin, H.; Lavigne, P.

1986-01-01

The first experimental observations of acceleration of injected electrons in a laser driven plasma beatwave are presented. The plasma waves were excited in an ionized gas jet, using a short pulse high intensity CO 2 laser with two collinearly propagating beams (at λ = 9.6 μm and 10.6 μm) to excite a fast wave (v/sub p/ = c). The source of electrons was a laser plasma produced on an aluminum slab target by a third, synchronized CO 2 laser beam. A double-focusing dipole magnet was used to energy select and inject electrons into the beatwave, and a second magnetic spectrograph was used to analyze the accelerated electrons. Electron acceleration was only observed when the appropriate resonant plasma density was produced (∼ 10 17 cm -3 ), the two laser lines were incident on the plasma, and electrons were injected into this plasma from an external source
Performance of the DIII-D neutral beam injection system

International Nuclear Information System (INIS)

Kim, J.; Callis, R.W.; Colleraine, A.P.; Cummings, J.; Glad, A.S.; Gootgeld, A.M.; Haskovec, J.S.; Hong, R.; Kellman, D.H.; Langhorn, A.R.

1987-01-01

During the upgrade of the Doublet III tokamak, the neutral beam injection system as also modified to accommodate long pulse sources and to utilize the larger entrance apertures to the torus vessel. All four beamlines on DIII-D are now in operation with a total of eight common long pulse sources. These have exhibited easier conditioning and good reproducibility. Performance results of the beamlines and supporting systems are presented, and the observed beam properties are discussed
Flavor and Functional Characteristics of Whey Protein Isolates from Different Whey Sources.

Science.gov (United States)

Smith, T J; Foegeding, E A; Drake, M A

2016-04-01

This study evaluated flavor and functional characteristics of whey protein isolates (WPIs) from Cheddar, Mozzarella, Cottage cheese, and rennet casein whey. WPIs were manufactured in triplicate. Powders were rehydrated and evaluated in duplicate by descriptive sensory analysis. Volatile compounds were extracted by solid-phase microextraction followed by gas chromatography-mass spectrometry. Functional properties were evaluated by measurement of foam stability, heat stability, and protein solubility. WPI from Cheddar and Cottage cheese whey had the highest cardboard flavor, whereas sweet aromatic flavor was highest in Mozzarella WPI, and rennet casein WPI had the lowest overall flavor and aroma. Distinct sour taste and brothy/potato flavor were also noted in WPI from Cottage cheese whey. Consistent with sensory results, aldehyde concentrations were also highest in Cheddar and Cottage cheese WPI. Overrun, yield stress, and foam stability were not different (P > 0.05) among Cheddar, Mozzarella, and rennet casein WPI, but WPI foams from Cottage cheese whey had a lower overrun and air-phase fraction (P whey sources could be used in new applications due to distinct functional and flavor characteristics. © 2016 Institute of Food Technologists®
Comparison of radiosensitivity of bacteria isolated from given radiation exposure history

International Nuclear Information System (INIS)

Kim, K.S.; Min, B.H.; Rhee, K.S.

1974-01-01

This experiment was carried out to identify and to compare the radiosensitivities of bacteria isolated from the sources of different radiation exposure histories. Among 10 strains isolated in this investigation, 4 strains of bacteria, Bacillus firmus, Bacillus brevis, Bacillus subtilis and Bacillus sphaericus were isolated from high- and low-radioactive sites simultaneously. Bacterial strains isolated from radioactive sources such as reactor and isotope production rooms were more resistant to irradiation than the microorganisms from medical products and laboratories, however, there was no significance in radiosensitivity in the same species of bacteria, even if they were isolated from different radiation exposure histories. (author)
Assessing genetic heterogeneity within bacterial species isolated from gastrointestinal and environmental samples: How many isolates does it take?

NARCIS (Netherlands)

Dopfer, D.; Buist, W.; Soyer, Y.; Munoz, M.A.; Zadoks, R.N.; Geue, L.; Engel, B.

2008-01-01

Strain typing of bacterial isolates is increasingly used to identify sources of infection or product contamination and to elucidate routes of transmission of pathogens or spoilage organisms. Usually, the number of bacterial isolates belonging to the same species that is analyzed per sample is
Temperature field distribution of coal seam in heat injection

OpenAIRE

Zhang Zhizhen; Peng Weihong; Shang Xiaoji; Wang Kun; Li Heng; Ma Wenming

2017-01-01

In this article, we present a natural boundary element method (NBEM) to solve the steady heat flow problem with heat sources in a coal seam. The boundary integral equation is derived to obtain the temperature filed distribution of the coal seam under the different injecting conditions.
Genetic diversity and antimicrobial resistance of Escherichia coli from human and animal sources uncovers multiple resistances from human sources.

Directory of Open Access Journals (Sweden)

A Mark Ibekwe

Full Text Available Escherichia coli are widely used as indicators of fecal contamination, and in some cases to identify host sources of fecal contamination in surface water. Prevalence, genetic diversity and antimicrobial susceptibility were determined for 600 generic E. coli isolates obtained from surface water and sediment from creeks and channels along the middle Santa Ana River (MSAR watershed of southern California, USA, after a 12 month study. Evaluation of E. coli populations along the creeks and channels showed that E. coli were more prevalent in sediment compared to surface water. E. coli populations were not significantly different (P = 0.05 between urban runoff sources and agricultural sources, however, E. coli genotypes determined by pulsed-field gel electrophoresis (PFGE were less diverse in the agricultural sources than in urban runoff sources. PFGE also showed that E. coli populations in surface water were more diverse than in the sediment, suggesting isolates in sediment may be dominated by clonal populations.Twenty four percent (144 isolates of the 600 isolates exhibited resistance to more than one antimicrobial agent. Most multiple resistances were associated with inputs from urban runoff and involved the antimicrobials rifampicin, tetracycline, and erythromycin. The occurrence of a greater number of E. coli with multiple antibiotic resistances from urban runoff sources than agricultural sources in this watershed provides useful evidence in planning strategies for water quality management and public health protection.
Acupuncture Injection Combined with Electrokinetic Injection for Polydimethylsiloxane Microfluidic Devices

Directory of Open Access Journals (Sweden)

Ji Won Ha

2017-01-01

Full Text Available We recently reported acupuncture sample injection that leads to reproducible injection of nL-scale sample segments into a polydimethylsiloxane (PDMS microchannel for microchip capillary electrophoresis. The advantages of the acupuncture injection in microchip capillary electrophoresis include capability of minimizing sample loss and voltage control hardware and capability of introducing sample plugs into any desired position of a microchannel. However, the challenge in the previous study was to achieve reproducible, pL-scale sample injections into PDMS microchannels. In the present study, we introduce an acupuncture injection technique combined with electrokinetic injection (AICEI technique to inject pL-scale sample segments for microchip capillary electrophoresis. We carried out the capillary zone electrophoresis (CZE separation of FITC and fluorescein, and the mixture of 10 μM FITC and 10 μM fluorescein was separated completely by using the AICEI method.
Beam-beam dynamics during the injection process at the PEP-II B-Factory

International Nuclear Information System (INIS)

Chin, Yong Ho.

1991-10-01

This paper is concerned with beam-beam effects during the injection process at the proposed asymmetric SLAC/LBL/LLNL B-Factory based on PEP (PEP-2). For symmetric colliders, the primary source of the beam-beam effect is the head-on collision at the interaction point (IP), and this effect can be mitigated by separating the beams during the injection process. For an asymmetric collider, which intrinsically consists of two separate rings, the bunches not only collide at the IP but experience a long-range beam-beam force on the way into and out of the IP region. These collisions are called ''parasitic crossings (PC).'' The parasitic crossings emerge as a potential source of far stronger beam-beam impact during the injection process for the following reason. In the proposed injection scheme of the APIARY-6.3d design, the bunches are injected horizontally into the two rings with large horizontal offset of 8σ Ox sptm where σ Ox sptm is the nominal horizontal storage ring beam size at the end of the septum magnet. Then, the injected beam starts to travel around the ring oscillating horizontally. For the sake of discussion, let us assume that the beam in the other ring has already been fully stored. When the injected beam arrives at the 1st PC, where the two nominal orbits are separated horizontally by about 7.6 times the nominal horizontal beam size of the low energy ring, it may pass through the other beam far more closely than at the nominal separation distance, or it may even strike the other beam head-on
Spin Injection in Indium Arsenide

Directory of Open Access Journals (Sweden)

Mark eJohnson

2015-08-01

Full Text Available In a two dimensional electron system (2DES, coherent spin precession of a ballistic spin polarized current, controlled by the Rashba spin orbit interaction, is a remarkable phenomenon that’s been observed only recently. Datta and Das predicted this precession would manifest as an oscillation in the source-drain conductance of the channel in a spin-injected field effect transistor (Spin FET. The indium arsenide single quantum well materials system has proven to be ideal for experimental confirmation. The 2DES carriers have high mobility, low sheet resistance, and high spin orbit interaction. Techniques for electrical injection and detection of spin polarized carriers were developed over the last two decades. Adapting the proposed Spin FET to the Johnson-Silsbee nonlocal geometry was a key to the first experimental demonstration of gate voltage controlled coherent spin precession. More recently, a new technique measured the oscillation as a function of channel length. This article gives an overview of the experimental phenomenology of the spin injection technique. We then review details of the application of the technique to InAs single quantum well (SQW devices. The effective magnetic field associated with Rashba spin-orbit coupling is described, and a heuristic model of coherent spin precession is presented. The two successful empirical demonstrations of the Datta Das conductance oscillation are then described and discussed.

A contoured gap coaxial plasma gun with injected plasma armature.

Science.gov (United States)

Witherspoon, F Douglas; Case, Andrew; Messer, Sarah J; Bomgardner, Richard; Phillips, Michael W; Brockington, Samuel; Elton, Raymond

2009-08-01

A new coaxial plasma gun is described. The long term objective is to accelerate 100-200 microg of plasma with density above 10(17) cm(-3) to greater than 200 km/s with a Mach number above 10. Such high velocity dense plasma jets have a number of potential fusion applications, including plasma refueling, magnetized target fusion, injection of angular momentum into centrifugally confined mirrors, high energy density plasmas, and others. The approach uses symmetric injection of high density plasma into a coaxial electromagnetic accelerator having an annular gap geometry tailored to prevent formation of the blow-by instability. The injected plasma is generated by numerous (currently 32) radially oriented capillary discharges arranged uniformly around the circumference of the angled annular injection region of the accelerator. Magnetohydrodynamic modeling identified electrode profiles that can achieve the desired plasma jet parameters. The experimental hardware is described along with initial experimental results in which approximately 200 microg has been accelerated to 100 km/s in a half-scale prototype gun. Initial observations of 64 merging injector jets in a planar cylindrical testing array are presented. Density and velocity are presently limited by available peak current and injection sources. Steps to increase both the drive current and the injected plasma mass are described for next generation experiments.
A contoured gap coaxial plasma gun with injected plasma armature

International Nuclear Information System (INIS)

Witherspoon, F. Douglas; Case, Andrew; Messer, Sarah J.; Bomgardner, Richard II; Phillips, Michael W.; Brockington, Samuel; Elton, Raymond

2009-01-01

A new coaxial plasma gun is described. The long term objective is to accelerate 100-200 μg of plasma with density above 10 17 cm -3 to greater than 200 km/s with a Mach number above 10. Such high velocity dense plasma jets have a number of potential fusion applications, including plasma refueling, magnetized target fusion, injection of angular momentum into centrifugally confined mirrors, high energy density plasmas, and others. The approach uses symmetric injection of high density plasma into a coaxial electromagnetic accelerator having an annular gap geometry tailored to prevent formation of the blow-by instability. The injected plasma is generated by numerous (currently 32) radially oriented capillary discharges arranged uniformly around the circumference of the angled annular injection region of the accelerator. Magnetohydrodynamic modeling identified electrode profiles that can achieve the desired plasma jet parameters. The experimental hardware is described along with initial experimental results in which approximately 200 μg has been accelerated to 100 km/s in a half-scale prototype gun. Initial observations of 64 merging injector jets in a planar cylindrical testing array are presented. Density and velocity are presently limited by available peak current and injection sources. Steps to increase both the drive current and the injected plasma mass are described for next generation experiments.
Development of injection moulded, ultrasonically welded immiscible phase filtration devices

DEFF Research Database (Denmark)

Kistrup, Kasper

for ultrasonic welding, suitable for microfluidic systems. A methodology has been established where energy directors can be quickly added to existing mould inserts, using laser micromachining. The produced device was performance tested by isolating methicillin-resistant Staphylococcus aureus from bovine whole....... The device appliesmagnetic bead-based solid-phase extraction for nucleic acid extraction from biological samples, using the immiscible phase filtration (IPF) approach. Device development has employed injection moulding for part fabrication and ultrasonic welding for bonding. Rapid prototyping...
Local Helicity Injection Systems for Non-solenoidal Startup in the PEGASUS Toroidal Experiment

Science.gov (United States)

Perry, J. M.; Barr, J. L.; Bongard, M. W.; Fonck, R. J.; Hinson, E. T.; Lewicki, B. T.; Redd, A. J.

2013-10-01

Local helicity injection is being developed in the PEGASUS Toroidal Experiment for non-solenoidal startup in spherical tokamaks. The effective loop voltage due to helicity injection scales with the area of the injectors, requiring the development of electron current injectors with areas much larger than the 2 cm2 plasma arc injectors used to date. Solid and gas-effused metallic electrodes were found to be unusable due to reduced injector area utilization from localized cathode spots and narrow operational regimes. An integrated array of 8 compact plasma arc sources is thus being developed for high current startup. It employs two monolithic power systems, for the plasma arc sources and the bias current extraction system. The array effectively eliminates impurity fueling from plasma-material interaction by incorporating a local scraper-limiter and conical-frustum bias electrodes to mitigate the effects of cathode spots. An energy balance model of helicity injection indicates that the resulting 20 cm2 of total injection area should provide sufficient current drive to reach 0.3 MA. At that level, helicity injection drive exceeds that from poloidal induction, which is the relevant operational regime for large-scale spherical tokamaks. Future placement of the injector array near an expanded boundary divertor region will test simultaneous optimization of helicity drive and the Taylor relaxation current limit. Work supported by US DOE Grant DE-FG02-96ER54375.
Source terms; isolation and radiological consequences of carbon-14 waste in the Swedish SFR repository

International Nuclear Information System (INIS)

Hesboel, R.; Puigdomenech, I.; Evans, S.

1990-01-01

The source term, isolation capacity, and long-term radiological exposure of 14 C from the Swedish underground repository for low and intermediate level waste (SFR) is assessed. The prospective amount of 14 C in the repository is assumed to be 5 TBq. Spent ion exchange resins will be the dominant source of 14 C. The pore water in the concrete repository is expected to maintain a pH of >10.5 for a period of at least 10 6 y. The cement matrix of the repository will retain most of the 14 CO 3 2- initially present. Bacterial production of CO 2 and CH 4 from degradation of ion-exchange resins and bitumen may contribute to 14 C release to the biosphere. However, CH 4 contributes only to a small extent to the overall carbon loss from freshwater ecosystems. The individual doses to local and regional individuals peaked with 5x10 -3 and regional individuals peaked with 5x10 -3 and 8x10 -4 μSv y -1 respectively at about 2.4x10 4 years. A total leakage of 8.4 GBq of 14 C from the repository will cause a total collective dose commitment of 1.1 manSv or 130 manSv TBq -1 . (authors)
Compressed air injection technique to standardize block injection pressures.

Science.gov (United States)

Tsui, Ban C H; Li, Lisa X Y; Pillay, Jennifer J

2006-11-01

Presently, no standardized technique exists to monitor injection pressures during peripheral nerve blocks. Our objective was to determine if a compressed air injection technique, using an in vitro model based on Boyle's law and typical regional anesthesia equipment, could consistently maintain injection pressures below a 1293 mmHg level associated with clinically significant nerve injury. Injection pressures for 20 and 30 mL syringes with various needle sizes (18G, 20G, 21G, 22G, and 24G) were measured in a closed system. A set volume of air was aspirated into a saline-filled syringe and then compressed and maintained at various percentages while pressure was measured. The needle was inserted into the injection port of a pressure sensor, which had attached extension tubing with an injection plug clamped "off". Using linear regression with all data points, the pressure value and 99% confidence interval (CI) at 50% air compression was estimated. The linearity of Boyle's law was demonstrated with a high correlation, r = 0.99, and a slope of 0.984 (99% CI: 0.967-1.001). The net pressure generated at 50% compression was estimated as 744.8 mmHg, with the 99% CI between 729.6 and 760.0 mmHg. The various syringe/needle combinations had similar results. By creating and maintaining syringe air compression at 50% or less, injection pressures will be substantially below the 1293 mmHg threshold considered to be an associated risk factor for clinically significant nerve injury. This technique may allow simple, real-time and objective monitoring during local anesthetic injections while inherently reducing injection speed.
A LIMIT ON THE NUMBER OF ISOLATED NEUTRON STARS DETECTED IN THE ROSAT ALL-SKY-SURVEY BRIGHT SOURCE CATALOG

International Nuclear Information System (INIS)

Turner, Monica L.; Rutledge, Robert E.; Letcavage, Ryan; Shevchuk, Andrew S. H.; Fox, Derek B.

2010-01-01

Using new and archival observations made with the Swift satellite and other facilities, we examine 147 X-ray sources selected from the ROSAT All-Sky-Survey Bright Source Catalog (RASS/BSC) to produce a new limit on the number of isolated neutron stars (INSs) in the RASS/BSC, the most constraining such limit to date. Independent of X-ray spectrum and variability, the number of INSs is ≤48 (90% confidence). Restricting attention to soft (kT eff < 200 eV), non-variable X-ray sources-as in a previous study-yields an all-sky limit of ≤31 INSs. In the course of our analysis, we identify five new high-quality INS candidates for targeted follow-up observations. A future all-sky X-ray survey with eROSITA, or another mission with similar capabilities, can be expected to increase the detected population of X-ray-discovered INSs from the 8-50 in the BSC, to (for a disk population) 240-1500, which will enable a more detailed study of neutron star population models.
Vibration analysis of the Golfech 2 safety injection system

International Nuclear Information System (INIS)

Morilhat, P.

1993-01-01

The main function of the safety injection system in a PWR plant is to ensure cooling of fuel elements in the event of a loss of coolant accident. The multistage centrifugal pump mounted-on this system induces pressure fluctuations, resulting in dynamic loads on piping. In certain plant units, these loads have caused cracking in the nozzles connected to the safety injection system, whereas in others, no damage has been observed. In order to understand the differences in dynamic behavior observed from one site to another, tests were performed on a real safety injection system, that of Golfech-2. They enabled determination of the modal characteristics of the system and identification of the hydro-acoustic source of the low head safety injection pump. They also enabled assessment of the pressure fluctuation levels in the pump suction and discharge areas as well as the vibratory response of the system when operating under partial and nominal flow conditions. Finally, these test results were used to estimate fatigue damage in the safety injection system. The experimental results will later be used to validate the model of the system undertaken with the piping design code CIRCUS and define the boundary conditions to be taken into account. (author). 6 figs., 2 refs
Passive and active vibration isolation systems using inerter

Science.gov (United States)

Alujević, N.; Čakmak, D.; Wolf, H.; Jokić, M.

2018-03-01

This paper presents a theoretical study on passive and active vibration isolation schemes using inerter elements in a two degree of freedom (DOF) mechanical system. The aim of the work is to discuss basic capabilities and limitations of the vibration control systems at hand using simple and physically transparent models. Broad frequency band dynamic excitation of the source DOF is assumed. The purpose of the isolator system is to prevent vibration transmission to the receiving DOF. The frequency averaged kinetic energy of the receiving mass is used as the metric for vibration isolation quality. It is shown that the use of inerter element in the passive vibration isolation scheme can enhance the isolation effect. In the active case, a feedback disturbance rejection scheme is considered. Here, the error signal is the receiving body absolute velocity which is directly fed to a reactive force actuator between the source and the receiving bodies. In such a scheme, the so-called subcritical vibration isolation problems exist. These problems are characterised by the uncoupled natural frequency of the receiving body larger than the uncoupled natural frequency of the source body. In subcritical vibration isolation problems, the performance of the active control is limited by poor stability margins. This is because the stable feedback gain is restricted in a narrow range between a minimum and a maximum. However, with the inclusion of an inerter in the isolator, one of the two stability margins can be opened. This enables large, theoretically unlimited negative feedback gains and large active damping of the receiving body vibration. A simple expression for the required inertance is derived.
[Evaluation of administration errors of injectable drugs in neonatology].

Science.gov (United States)

Cherif, A; Sayadi, M; Ben Hmida, H; Ben Ameur, K; Mestiri, K

2015-11-01

Use of injectable drugs in newborns represents more than 90% of prescriptions and requires special precautions in order to ensure more safety and efficiency. The aim of this study is to gather errors relating to the administration of injectable drugs and to suggest corrective actions. This descriptive and transversal study has evaluated 300 injectable drug administrations in a neonatology unit. Two hundred and sixty-one administrations have contained an error. Data are collected by direct observations of administrative act. Errors observed are: an inappropriate mixture (2.6% of cases); an incorrect delivery rate (33.7% of cases); incorrect dilutions (26.7% of cases); error in calculation of the dose to be injected (16.7% of cases); error while sampling small volumes (6.3% of cases); error or omission of administration schedule (1% of cases). These data have enabled us to evaluate administration of injectable drugs in neonatology. Different types of errors observed could be a source of therapeutic inefficiency, extended lengths of stay or iatrogenic drug. Following these observations, corrective actions have been undertaken by pharmacists and consist of: organizing training sessions for nursing; developing an explanatory guide for dilution and administration of injectable medicines, which was made available to the clinical service. Collaborative strategies doctor-nurse-pharmacist can help to reduce errors in the medication process especially during his administration. It permits improvement of injectable drugs use, offering more security and better efficiency and contribute to guarantee ideal therapy for patients. Copyright © 2015. Published by Elsevier Masson SAS.
VSP Monitoring of CO2 Injection at the Aneth Oil Field in Utah

Science.gov (United States)

Huang, L.; Rutledge, J.; Zhou, R.; Denli, H.; Cheng, A.; Zhao, M.; Peron, J.

2008-12-01

Remotely tracking the movement of injected CO2 within a geological formation is critically important for ensuring safe and long-term geologic carbon sequestration. To study the capability of vertical seismic profiling (VSP) for remote monitoring of CO2 injection, a geophone string with 60 levels and 96 channels was cemented into a monitoring well at the Aneth oil field in Utah operated by Resolute Natural Resources and Navajo National Oil and Gas Company. The oil field is located in the Paradox Basin of southeastern Utah, and was selected by the Southwest Regional Partnership on Carbon Sequestration, supported by the U.S. Department of Energy, to demonstrate combined enhanced oil recovery (EOR) and CO2 sequestration. The geophones are placed at depths from 805 m to 1704 m, and the oil reservoir is located approximately from 1731 m to 1786 m in depth. A baseline VSP dataset with one zero-offset and seven offset source locations was acquired in October, 2007 before CO2 injection. The offsets/source locations are approximately 1 km away from the monitoring well with buried geophone string. A time-lapse VSP dataset with the same source locations was collected in July, 2008 after five months of CO2/water injection into a horizontal well adjacent to the monitoring well. The total amount of CO2 injected during the time interval between the two VSP surveys was 181,000 MCF (million cubic feet), or 10,500 tons. The time-lapse VSP data are pre-processed to balance the phase and amplitude of seismic events above the oil reservoir. We conduct wave-equation migration imaging and interferometry analysis using the pre-processed time-lapse VSP data. The results demonstrate that time-lapse VSP surveys with high-resolution migration imaging and scattering analysis can provide reliable information about CO2 migration. Both the repeatability of VSP surveys and sophisticated time-lapse data pre-processing are essential to make VSP as an effective tool for monitoring CO2 injection.
Linac4: injecting new life into the LHC

CERN Multimedia

Antonella Del Rosso

2015-01-01

Construction work is nearing completion on the ion source for Linac4, the new linear accelerator that forms part of the LHC injector upgrade programme. Here we find out more about this essential component of the accelerator chain, designed and built at CERN. The image shows the Linac4 H- source. The red light is the alpha line of the visible hydrogen emission spectrum. The ion source is a key component of Linac4, the linear accelerator that from 2018 will supply H- ions (hydrogen atoms with an extra electron) at 160 MeV for injection into the accelerator complex. As the only ion source at CERN, Linac4 must be highly reliable, which requires a full understanding of the production mechanisms, the simulation of physical processes and the validation of those processes through experimentation. “This source is the result of much fruitful collaboration,” says Jacques Lettry of the BE department. “Its design was inspired by the many sources of th...
Biosurfactant production by yeasts isolated from hydrocarbon polluted environments.

Science.gov (United States)

Kaur, Kamalpreet; Sangwan, Seema; Kaur, Harpreet

2017-11-03

Thirty-two yeast isolates were retrieved from four soil samples collected from hydrocarbon-polluted locations of Hisar, Haryana, using enrichment culture technique with 1% (v/v) diesel as carbon source. Total nine isolates showing blood agar haemolysis were screened further for biosurfactant production. Yeast isolate, YK32, gave highest 8.4-cm oil displacement which was found to be significantly higher as compared to positive control, 0.2% (w/v) SDS (6.6 cm), followed by 6.2 and 6.0 cm by isolates YK20 and YK21, respectively. Maximum emulsification index was obtained in case of isolates YK20 and YK21 measuring 53.8%, after 6 days of incubation utilizing glucose as carbon source, whereas isolate YK32 was found to be reducing surface tension up to 93 dynes/cm and presented 99.6% degree of hydrophobicity. Olive oil has supported maximum surface tension reduction in isolates YK32 and YK21 equivalent to 53 and 48 dynes/cm and gave 88.3 and 88.5% degree of hydrophobicity, respectively. Diesel was not preferred as carbon source by most of the isolates except YK28 which generated 5.5-cm oil displacement, 25% emulsification index, reduced surface tension to the level of 38 dynes/cm and presented 89% degree of hydrophobicity. Conclusively, isolates YK20, YK21, YK22 and YK32 were marked as promising biosurfactant producers and were subjected to identification. Based on microscopic examination and biochemical peculiarities, isolates YK21 and YK22 might be identified as Candida spp., whereas, isolates YK20 and YK32 might be identified as Saccharomycopsis spp. and Brettanomyces spp., respectively. Interestingly it is the first report indicating Saccharomycopsis spp. and Brettanomyces spp. as a potential biosurfactant producer.
Electron injection dynamics in high-potential porphyrin photoanodes.

Science.gov (United States)

Milot, Rebecca L; Schmuttenmaer, Charles A

2015-05-19

There is a growing need to utilize carbon neutral energy sources, and it is well known that solar energy can easily satisfy all of humanity's requirements. In order to make solar energy a viable alternative to fossil fuels, the problem of intermittency must be solved. Batteries and supercapacitors are an area of active research, but they currently have relatively low energy-to-mass storage capacity. An alternative and very promising possibility is to store energy in chemical bonds, or make a solar fuel. The process of making solar fuel is not new, since photosynthesis has been occurring on earth for about 3 billion years. In order to produce any fuel, protons and electrons must be harvested from a species in its oxidized form. Photosynthesis uses the only viable source of electrons and protons on the scale needed for global energy demands: water. Because artificial photosynthesis is a lofty goal, water oxidation, which is a crucial step in the process, has been the initial focus. This Account provides an overview of how terahertz spectroscopy is used to study electron injection, highlights trends from previously published reports, and concludes with a future outlook. It begins by exploring similarities and differences between dye-sensitized solar cells (DSSCs) for producing electricity and a putative device for splitting water and producing a solar fuel. It then identifies two important problems encountered when adapting DSSC technology to water oxidation-improper energy matching between sensitizer energy levels with the potential for water oxidation and the instability of common anchoring groups in water-and discusses steps to address them. Emphasis is placed on electron injection from sensitizers to metal oxides because this process is the initial step in charge transport. Both the rate and efficiency of electron injection are analyzed on a sub-picosecond time scale using time-resolved terahertz spectroscopy (TRTS). Bio-inspired pentafluorophenyl porphyrins are
'It's Fast, It's Quick, It Stops Me Being Sick': How to influence preparation of opioid tablets for injection.

Science.gov (United States)

Lafferty, Lise; Treloar, Carla; van Breda, Nick; Steele, Maureen; Hiley, Sarah; Flaherty, Ian; Salmon, Allison

2017-09-01

Injection of pharmaceutical opioids (PO) among people who inject drugs has increased in many countries. The common method for preparing PO tablets for injection uses heat, resulting in greater particulate matter and therefore increased risk of local infection risk and damage to veins and organs. A cold preparation process has fewer risks, but this preparation method is not commonly used. This study seeks to explore how people who inject PO learn to prepare injections and how health promotion efforts could influence practice. Between March and December 2013, qualitative interviews were undertaken with 33 clients of Sydney's Medically Supervised Injecting Centre who inject PO tablets regarding sources of knowledge and current preparation methods for injection of POs. Overwhelmingly, the most commonly reported source of knowledge around injection of tablets was others who inject. Most participants reported heating the solution as the quickest way to administer the drug. Attitudes to the use of wheel filters varied, with some participants reporting that they would use the filters if they were shown how, while others reported a number of barriers to using filters, including complexity of use. Harnessing the power of social connections may provide avenues for education about safer injecting of tablets, including the use of wheel filters. Further work is required to debunk myths about the relative potencies of cold versus hot drug solution. Collaborations between harm reduction workers and peer workers would assist in knowledge dissemination regarding safer injecting practices. © 2017 Australasian Professional Society on Alcohol and other Drugs.
Muscle changes can account for bone loss after botulinum toxin injection.

Science.gov (United States)

Manske, Sarah L; Boyd, Steven K; Zernicke, Ronald F

2010-12-01

Studies to date have assumed that botulinum toxin type A (BTX) affects bone indirectly, through its action on muscle. We hypothesized that BTX has no discernable effect on bone morphometry, independent of its effect on muscle. Therefore, we investigated whether BTX had an additional effect on bone when combined with tenotomy compared to tenotomy in isolation. Female BALB/c mice (n = 73) underwent one of the following procedures in the left leg: BTX injection and Achilles tenotomy (BTX-TEN), BTX injection and sham surgery (BTX-sham), Achilles tenotomy (TEN), or sham surgery (sham). BTX groups were injected with 20 μL of BTX (1 U/100 g) in the posterior lower hindlimb. At 4 weeks, muscle cross-sectional area (MCSA) and tibial bone morphometry were assessed using micro-CT. Each treatment, other than sham, resulted in significant muscle and bone loss (P properties. We found that BTX injection resulted in more adverse muscle and bone effects than tenotomy and that effects were amplified when the procedures were combined. However, between-group differences in bone could be accounted for by MCSA. We conclude that any independent effect of BTX on bone morphometry is likely small or negligible compared with the effect on muscle.
Shrimp pathogenicity, hemolysis, and the presence of hemolysin and TTSS genes in Vibrio harveyi isolated from Thailand.

Science.gov (United States)

Rattanama, Pimonsri; Srinitiwarawong, Kanchana; Thompson, Janelle R; Pomwised, Rattanaruji; Supamattaya, Kidchakarn; Vuddhakul, Varaporn

2009-09-23

The virulence factors of Vibrio harveyi, the causative agent of luminous vibriosis, are not completely understood. We investigated the correlations between shrimp mortality, hemolysis, the presence of a hemolysin gene (vhh), and a gene involved in the type III secretion system (the Vibrio calcium response gene vcrD). V harveyi HY01 was isolated from a shrimp that died from vibriosis, and 36 other V. harveyi isolates were obtained from fish and shellfish in Hat Yai city, Thailand. An ocean isolate of V. harveyi BAA-1116 was also included. Thirteen isolates including V harveyi HYO1 caused shrimp death 12 h after injection. Most V harveyi isolates in this group (designated as Group A) caused hemolysis on prawn blood agar. None of the shrimp died after injection with V harveyi BAA-1116. Molecular analysis of all V harveyi isolates revealed the presence of vcrD in both pathogenic and non-pathogenic strains. Although vhh was detected in all V harveyi isolates, some isolates did not cause hemolysis, indicating that vhh gene expression might be regulated. Analysis of the V harveyi HYO1 genome revealed a V cholerae like-hemolysin gene, hlyA (designated as hhl). Specific primers designed for hhl detected this gene in 3 additional V harveyi isolates but the presence of this gene was not correlated with pathogenicity. Random amplified polymorphic DNA (RAPD) analysis revealed a high degree of genetic diversity in all V harveyi isolates, and there were no correlations among the hhl-positive isolates or the pathogenic strains.
Microvascular complications associated with injection of cosmetic facelift dermal fillers

Science.gov (United States)

Yousefi, Siavash; Prendes, Mark; Chang, Shu-Hong; Wang, Ruikang K.

2015-02-01

Minimally-invasive cosmetic surgeries such as injection of subdermal fillers have become very popular in the past decade. Although rare, some complications may follow injections such as tissue necrosis and even blindness. There exist two hypothesis regarding source of these complications both of which include microvasculature. The first hypothesis is that fillers in between the tissue structures and compress microvasculature that causes blockage of tissue neutrition and oxygen exchange in the tissue. In another theory, it is hypothesized that fillers move inside major arteries and block the arteries/veins. In this paper, we study these hypotheses using optical coherence tomography and optical microangiography technologies with different hyaluronic-acid fillers in a mouse ear model. Based on our observations, the fillers eventually block arteries/veins if injected directly into them that eventually causes tissue necrosis.
Isolation and characterization of yeasts capable of efficient utilization of hemicellulosic hydrolyzate as the carbon source.

Science.gov (United States)

Cassa-Barbosa, L A; Procópio, R E L; Matos, I T S R; Filho, S A

2015-09-28

Few yeasts have shown the potential to efficiently utilize hemicellulosic hydrolyzate as the carbon source. In this study, microorganisms isolated from the Manaus region in Amazonas, Brazil, were characterized based on their utilization of the pentoses, xylose, and arabinose. The yeasts that showed a potential to assimilate these sugars were selected for the better utilization of lignocellulosic biomass. Two hundred and thirty seven colonies of unicellular microorganisms grown on hemicellulosic hydrolyzate, xylose, arabinose, and yeast nitrogen base selective medium were analyzed. Of these, 231 colonies were subjected to sugar assimilation tests. One hundred and twenty five of these were shown to utilize hydrolyzed hemicellulose, xylose, or arabinose as the carbon source for growth. The colonies that showed the best growth (N = 57) were selected, and their internal transcribed spacer-5.8S rDNA was sequenced. The sequenced strains formed four distinct groups in the phylogenetic tree, and showed a high percentage of similarity with Meyerozyma caribbica, Meyerozyma guilliermondii, Trichosporon mycotoxinivorans, Trichosporon loubieri, Pichia kudriavzevii, Candida lignohabitans, and Candida ethanolica. The discovery of these xylose-fermenting yeasts could attract widespread interest, as these can be used in the cost-effective production of liquid fuel from lignocellulosic materials.
Safe injection procedures, injection practices, and needlestick ...

African Journals Online (AJOL)

Nermine Mohamed Tawfik Foda

2017-01-10

Jan 10, 2017 ... Background: Of the estimated 384,000 needle-stick injuries occurring in hospitals each year, 23% occur in surgical settings. This study was conducted to assess safe injection procedures, injection practices, and circumstances contributing to needlestick and sharps injures (NSSIs) in operating rooms.

Amino Acid Composition of an Organic Brown Rice Protein Concentrate and Isolate Compared to Soy and Whey Concentrates and Isolates

Directory of Open Access Journals (Sweden)

Douglas S. Kalman

2014-06-01

Full Text Available A protein concentrate (Oryzatein-80™ and a protein isolate (Oryzatein-90™ from organic whole-grain brown rice were analyzed for their amino acid composition. Two samples from different batches of Oryzatein-90™ and one sample of Oryzatein-80™ were provided by Axiom Foods (Los Angeles, CA, USA. Preparation and analysis was carried out by Covance Laboratories (Madison, WI, USA. After hydrolysis in 6-N hydrochloric acid for 24 h at approximately 110 °C and further chemical stabilization, samples were analyzed by HPLC after pre-injection derivitization. Total amino acid content of both the isolate and the concentrate was approximately 78% by weight with 36% essential amino acids and 18% branched-chain amino acids. These results are similar to the profiles of raw and cooked brown rice except in the case of glutamic acid which was 3% lower in the isolate and concentrate. The amino acid content and profile of the Oryzatein-90™ isolate was similar to published values for soy protein isolate but the total, essential, and branched-chain amino acid content of whey protein isolate was 20%, 39% and 33% greater, respectively, than that of Oryzatein-90™. These results provide a valuable addition to the nutrient database of protein isolates and concentrates from cereal grains.
Similarities between Salmonella Enteritidis isolated from humans and captive wild animals in South Africa.

Science.gov (United States)

Smith, Anthony M; Ismail, Husna; Henton, Maryke M; Keddy, Karen H

2014-12-15

Salmonella is well recognized as an aetiological agent of gastrointestinal and diarrhoeal disease. Salmonella enterica serotype Enteritidis (Salmonella Enteritidis) is one of the commonest serotypes associated with foodborne illness. In South Africa, we compared Salmonella Enteritidis strains isolated from humans with gastroenteritis and strains isolated from captive wild animals, between June 2011 and July 2012. Bacteria were phenotypically characterized using standard microbiological techniques. Genotypic relatedness of isolates was investigated by pulsed-field gel electrophoresis (PFGE) analysis. a diversity of 27 PFGE patterns amongst 196 human non-invasive isolates was shown; two PFGE patterns predominated and accounted for 74% of all human isolates. Human isolates showed a 12% prevalence rate for nalidixic acid resistance. Animal isolates from 5 different sources were investigated. With the exception of an isolate from a ground hornbill, all animal isolates (jaguar, crocodile, lion and poultry) showed PFGE pattern matches to a human isolate. Animal isolates showed susceptibility to all antimicrobial agents tested, with the exception of nalidixic acid resistance in isolates from the lion and poultry source. Our data showed similarities between Salmonella Enteritidis strains isolated from humans and captive wild animals, suggesting a probable common source for strains from humans and animals.
Zinc injection in German PWR plants

International Nuclear Information System (INIS)

Streit, K.

2004-01-01

Operating experience acquired at PWR NNPs shows that zinc injection at low concentrations of 5 ppb is a very effective source term reduction measure. This method does not lead to any operating restrictions or other negative effects on plant systems and components. The nuclear industry has been very successful in reducing radiation exposures within the past two decades. Annual exposures could be significantly decreased and are now at a level of around 1 man-Sv per plant and year. This great success can mainly be attributed to the general commitment of plant operators to maintaining radiation exposures of workers in the controlled access area as low as reasonably achievable (ALARA principle). The ALARA principle, of course, also implies evaluation of the economic benefit of radiation protection measures. Radiation source term reduction has drawn increasing attention of plant operators in recent years. For the new PWRs cobalt-based alloys in the primary system have successively been eliminated already at the design and construction phase within the last decade. Use of wear-resistant cobalt-free substitute materials in combination with the general use of advanced alloys for the steam generator tubing of PWRs resulted in low values for the two most common sources of plant radiation fields, namely 58 Co and 60 Co. Investigations showed that the beneficial effect of zinc can be related to its high affinity for mixed spinel oxide phases, resulting in the following two basic effects: -Zinc is incorporated preferentially into the oxide layer on primary system surfaces and thus reduces pickup of 58 Co and 60 Co and - Zinc can displace cobalt isotopes from existing oxide layers. In German PWRs with Incoloy 800 steam generator tubing material (Ni-content -32%), the observed reductions correspond to a decrease in dose rates of around 10 to 15% per year and thus follow, as predicted, the half-life time of 60 Co. Overall reductions in high radiation areas are now in the range of
INJECTION CARBON STRIPPING FOIL ISSUES IN THE SNS ACCUMULATOR RING

International Nuclear Information System (INIS)

BEEBE-WANG, J.; LEE, Y.Y.; RAPARIA, D.; WEI, J.

2001-01-01

We are reporting the results of studies on issues related to the injection stripping foil in the Spallation Neutron Source (SNS) accumulator ring. The problems related to foil heating and foil lifetime, such as current density distribution and temperature distribution in the foil, are investigated. The impact of injection errors on the beam losses at the foil is studied. The particle traversal rate and the beam losses due to scattering in the foil are summarized. Finally, SNS end-to-end simulation results of the foil-missing rate, the foil-hitting rate and the maximum foil temperature are presented
Genetic Attributes of E. coli Isolates from Chlorinated Drinking Water.

Science.gov (United States)

Blyton, Michaela D J; Gordon, David M

2017-01-01

Escherichia coli, is intimately associated with both human health and water sanitation. E. coli isolates from water can either be (i) host associated commensals, indicating recent faecal contamination; (ii) diarrheal pathogens or (iii) extra-intestinal pathogens that pose a direct health risk; or (iv) free-living. In this study we genetically characterised 28 E. coli isolates obtained from treated drinking water in south eastern Australia to ascertain their likely source. We used full genome sequencing to assign the isolates to their phylogenetic group and multi-locus sequence type. The isolates were also screened in silico for several virulence genes and genes involved in acquired antibiotic resistance. The genetic characteristics of the isolates indicated that four isolates were likely human pathogens. However, these isolates were not detected in sufficient numbers to present a health risk to the public. An additional isolate was a human associated strain. Nine isolates were water associated free-living strains that were unlikely to pose a health risk. Only 14% of the isolates belonged to the host associated phylogenetic group (B2) and only a single isolate had any antibiotic resistance genes. This suggests that the primary source of the drinking water E. coli isolates may not have been recent human faecal contamination.
Genetic Attributes of E. coli Isolates from Chlorinated Drinking Water.

Directory of Open Access Journals (Sweden)

Michaela D J Blyton

Full Text Available Escherichia coli, is intimately associated with both human health and water sanitation. E. coli isolates from water can either be (i host associated commensals, indicating recent faecal contamination; (ii diarrheal pathogens or (iii extra-intestinal pathogens that pose a direct health risk; or (iv free-living. In this study we genetically characterised 28 E. coli isolates obtained from treated drinking water in south eastern Australia to ascertain their likely source. We used full genome sequencing to assign the isolates to their phylogenetic group and multi-locus sequence type. The isolates were also screened in silico for several virulence genes and genes involved in acquired antibiotic resistance. The genetic characteristics of the isolates indicated that four isolates were likely human pathogens. However, these isolates were not detected in sufficient numbers to present a health risk to the public. An additional isolate was a human associated strain. Nine isolates were water associated free-living strains that were unlikely to pose a health risk. Only 14% of the isolates belonged to the host associated phylogenetic group (B2 and only a single isolate had any antibiotic resistance genes. This suggests that the primary source of the drinking water E. coli isolates may not have been recent human faecal contamination.
Betatron emission as a diagnostic for injection and acceleration mechanisms in laser plasma accelerators

International Nuclear Information System (INIS)

Corde, S; Thaury, C; Phuoc, K Ta; Lifschitz, A; Lambert, G; Lundh, O; Brijesh, P; Sebban, S; Rousse, A; Faure, J; Malka, V; Arantchuk, L

2012-01-01

Betatron x-ray emission in laser plasma accelerators is a promising compact source that may be an alternative to conventional x-ray sources, based on large scale machines. In addition to its potential as a source, precise measurements of betatron emission can reveal crucial information about relativistic laser–plasma interaction. We show that the emission length and the position of the x-ray emission can be obtained by placing an aperture mask close to the source, and by measuring the beam profile of the betatron x-ray radiation far from the aperture mask. The position of the x-ray emission gives information on plasma wave breaking and hence on the laser non-linear propagation. Moreover, the measurement of the longitudinal extension helps one to determine whether the acceleration is limited by pump depletion or dephasing effects. In the case of multiple injections, it is used to retrieve unambiguously the position in the plasma of each injection. This technique is also used to study how, in a capillary discharge, the variations of the delay between the discharge and the laser pulse affect the interaction. The study reveals that, for a delay appropriate for laser guiding, the x-ray emission only occurs in the second half of the capillary: no electrons are injected and accelerated in the first half. (paper)
A contoured gap coaxial plasma gun with injected plasma armature

Energy Technology Data Exchange (ETDEWEB)

Witherspoon, F. Douglas; Case, Andrew; Messer, Sarah J.; Bomgardner, Richard II; Phillips, Michael W.; Brockington, Samuel; Elton, Raymond [HyperV Technologies Corp., Chantilly, Virginia 20151 (United States)

2009-08-15

A new coaxial plasma gun is described. The long term objective is to accelerate 100-200 {mu}g of plasma with density above 10{sup 17} cm{sup -3} to greater than 200 km/s with a Mach number above 10. Such high velocity dense plasma jets have a number of potential fusion applications, including plasma refueling, magnetized target fusion, injection of angular momentum into centrifugally confined mirrors, high energy density plasmas, and others. The approach uses symmetric injection of high density plasma into a coaxial electromagnetic accelerator having an annular gap geometry tailored to prevent formation of the blow-by instability. The injected plasma is generated by numerous (currently 32) radially oriented capillary discharges arranged uniformly around the circumference of the angled annular injection region of the accelerator. Magnetohydrodynamic modeling identified electrode profiles that can achieve the desired plasma jet parameters. The experimental hardware is described along with initial experimental results in which approximately 200 {mu}g has been accelerated to 100 km/s in a half-scale prototype gun. Initial observations of 64 merging injector jets in a planar cylindrical testing array are presented. Density and velocity are presently limited by available peak current and injection sources. Steps to increase both the drive current and the injected plasma mass are described for next generation experiments.
Microwave plasma source for neutral-beam injection systems. Quarterly technical progress report

International Nuclear Information System (INIS)

1981-01-01

The overall program is described and the technical and programmatic reasons for the decision to pursue both the RFI and ECH sources into the current hydrogen test stage is discussed. We consider the general characteristics of plasma sources in the parameter regime of interest for neutral beam applications. The operatonal characteristics, advantages and potential problems of RFI and ECH sources are discussed. In these latter two sections we rely heavily on experience derived from developing RFI and ECH ion engine sources for NASA
Monitoring of density in tokamaks: pumping and gas injection; Controle de la densite dans les tokamaks: pompage et injection de matiere

Energy Technology Data Exchange (ETDEWEB)

Dejarnac, R

2002-11-01

In thermonuclear fusion devices, controlling the Deuterium-Tritium fuel density and exhausting the Helium ashes is a crucial point. This is achieved by fuelling the discharges by different methods (gas puffing and pellet injection are the most commonly used) and by implementing pumping devices at the plasma periphery. These two issues are treated in this work, both from an experimental and a modelling point of view, using the neutral transport code EIRENE as main tool for our studies. As far as pumping is concerned, we have modelled the outboard pump limiter of the Tore Supra tokamak with the EIRENE code to which we coupled a plasma module specially developed to simulate the neutrals and the plasma in a coherent way. This allowed to validate the code against experimental data. As far as plasma fuelling is concerned, we present here an original method: the supersonic pulsed gas injection (SPGI). This intermediate method between conventional gas puff (GP) and pellet injection was designed and tested at Tore Supra. It consists of injecting very dense and short gas puffs at high speed into the plasma. Experimentally, SPGI was found to have a better fuelling efficiency than GP and to lead to a strong plasma cooling. The mechanisms responsible for this improved efficiency are analysed by modelling, using the EIRENE code to determine the ionisation source and a 1 D transport model to reproduce the plasma density response. At last, an extrapolation of the present injector is presented, discussing the possibility to obtain a radial drift of the injected matter as observed in the case of high field side pellet injection. (author)
Prevalence and correlates of neck injection among people who inject drugs in Tijuana, Mexico.

Science.gov (United States)

Rafful, Claudia; Wagner, Karla D; Werb, Dan; González-Zúñiga, Patricia E; Verdugo, Silvia; Rangel, Gudelia; Strathdee, Steffanie A

2015-11-01

Injecting drugs in the neck has been related to adverse health conditions such as jugular vein thrombosis, deep neck infections, aneurysm, haematomas, airway obstruction, vocal cord paralysis and wound botulism, among others. We identified prevalence and correlates of neck injection among people who inject drugs (PWID) in Tijuana, Mexico. Beginning in 2011, PWID aged ≥18 years who injected drugs within the last month were recruited into a prospective cohort. At baseline and semi-annually, PWID completed interviewer-administered surveys soliciting data on drug-injecting practices. Logistic regression was used to identify predictors of injecting in the neck as the most frequent injection site at a single visit. Of 380 PWID, 35.3% injected in the neck at least once in the past 6 months, among whom 71.6% reported it as their most common injection site, the most common injecting site after the arms (47%). Controlling for age, years injecting and injecting frequency, injecting heroin and methamphetamine two or more times per day and having sought injection assistance were associated with injecting in the neck [adjusted odds ratios (AOR): 2.12; 95% confidence intervals (CI): 1.27-3.53 and AOR: 2.65; 95% CI: 1.52-4.53 respectively]. Injecting in the neck was very common among PWID in Tijuana and was associated with polydrug use and seeking injection assistance. Tailoring harm reduction education interventions for individuals who provide injection assistance ('hit doctors') may allow for the dissemination of safe injecting knowledge to reduce injection-related morbidity and mortality. © 2015 Australasian Professional Society on Alcohol and other Drugs.
The heavy ion injection scheme for RHIC [Relativistic Heavy Ion Collider

International Nuclear Information System (INIS)

Rhoades-Brown, M.J.

1989-01-01

The Relativistic Heavy Ion Collider (RHIC) at Brookhaven has a multi-component injection system. The Collider requires very heavy ions such as 79 197 Au to be injected fully stripped of atomic electrons, at a kinetic energy of approximately 10 GeV/nucleon. However, the heavy ions are produced initially at a negative ion source and accelerated first in a 15 MV Tandem. These partially stripped ions have a kinetic energy of approximately 1 MeV/nucleon on leaving the Tandem. In order to achieve the injection requirements for RHIC, the partially stripped ions are accelerated in the Booster (currently under construction) and pass through a stripping foil on their way to the Alternating Gradient Synchrotron (AGS), where they are further accelerated before injection into RHIC. Recent theoretical calculations have shown quite convincingly that very heavy ions with 2 electrons in the filled K-shell may be accelerated with negligible loss in the AGS. 13 refs., 3 figs., 3 tabs
Initial operation and performance of the PDX neutral-beam injection system

International Nuclear Information System (INIS)

Kugel, H.W.; Eubank, H.P.; Kozub, T.A.; Rossmassler, J.E.; Schilling, G.; van Halle, A.; Williams, M.D.

1982-01-01

In 1981, the joint ORNL/PPPL PDX neutral beam heating project succeeded in reliably injecting 7.2 MW of D 0 into the PDX plasma, at nearly perpendicular angles, and achieved ion temperatures up to 6.5 keV. The expeditious achievement of this result was due to the thorough conditioning and qualification of the PDX neutral beam ion sources at ORNL prior to delivery coupled with several field design changes and improvements in the injection system made at PPPL as a result of neutral beam operating experience with the PLT tokamak. It has been found that the operation of high power neutral beam injection systems in a tokamak-neutral beam environment requires procedures and performance different from those required for development operation on test stands. In this paper, we review the installatin of the PDX neutral beam injection system, and its operation and performance during the initial high power plasma heating experiments with the PDX tokamak
Small-Volume Injections: Evaluation of Volume Administration Deviation From Intended Injection Volumes.

Science.gov (United States)

Muffly, Matthew K; Chen, Michael I; Claure, Rebecca E; Drover, David R; Efron, Bradley; Fitch, William L; Hammer, Gregory B

2017-10-01

In the perioperative period, anesthesiologists and postanesthesia care unit (PACU) nurses routinely prepare and administer small-volume IV injections, yet the accuracy of delivered medication volumes in this setting has not been described. In this ex vivo study, we sought to characterize the degree to which small-volume injections (≤0.5 mL) deviated from the intended injection volumes among a group of pediatric anesthesiologists and pediatric postanesthesia care unit (PACU) nurses. We hypothesized that as the intended injection volumes decreased, the deviation from those intended injection volumes would increase. Ten attending pediatric anesthesiologists and 10 pediatric PACU nurses each performed a series of 10 injections into a simulated patient IV setup. Practitioners used separate 1-mL tuberculin syringes with removable 18-gauge needles (Becton-Dickinson & Company, Franklin Lakes, NJ) to aspirate 5 different volumes (0.025, 0.05, 0.1, 0.25, and 0.5 mL) of 0.25 mM Lucifer Yellow (LY) fluorescent dye constituted in saline (Sigma Aldrich, St. Louis, MO) from a rubber-stoppered vial. Each participant then injected the specified volume of LY fluorescent dye via a 3-way stopcock into IV tubing with free-flowing 0.9% sodium chloride (10 mL/min). The injected volume of LY fluorescent dye and 0.9% sodium chloride then drained into a collection vial for laboratory analysis. Microplate fluorescence wavelength detection (Infinite M1000; Tecan, Mannedorf, Switzerland) was used to measure the fluorescence of the collected fluid. Administered injection volumes were calculated based on the fluorescence of the collected fluid using a calibration curve of known LY volumes and associated fluorescence.To determine whether deviation of the administered volumes from the intended injection volumes increased at lower injection volumes, we compared the proportional injection volume error (loge [administered volume/intended volume]) for each of the 5 injection volumes using a linear
Characterisation of successive Acinetobacter baumannii isolates from a deceased haemophagocytic lymphohistiocytosis patient.

Science.gov (United States)

Choi, Hyeon Jin; Kil, Min Cheol; Choi, Ji-Young; Kim, Sun Ju; Park, Ki-Sup; Kim, Yae-Jean; Ko, Kwan Soo

2017-01-01

In this study, 38 Acinetobacter baumannii isolates successively isolated from blood, skin swabs and tracheal aspirates from a single patient who died from haemophagocytic lymphohistiocytosis were investigated. The isolates were collected between March 2012 and August 2012. A. baumannii genotypes were determined by multilocus sequence typing (MLST) and pulsed-field gel electrophoresis (PFGE). In vitro antimicrobial susceptibility testing was performed and colistin heteroresistance and persistence were evaluated. The structure of AbaR resistance islands was explored, and serum sensitivity was determined. Based on MLST analysis, all 38 A. baumannii isolates showed the same sequence type (ST138). However, PFGE analysis showed that isolates from blood samples belonged to different genotypes depending on the isolation time: whilst blood isolates obtained at the early stages showed restriction patterns similar to those of isolates from other sources, isolates obtained at later stages exhibited a distinct pattern. All isolates were resistant to imipenem, cefepime, ciprofloxacin and piperacillin/tazobactam. Five isolates from tracheal aspirates and one from a skin swab were resistant to polymyxins, and two isolates from skin swabs and one from another source were non-susceptible to tigecycline. All colistin-susceptible isolates showed heteroresistance to colistin, and four were persisters. Isolates from blood showed higher survival rates against human serum than those from other sources. This study shows that the patient was infected with more than one A. baumannii strain. Heteroresistance, persistence or evasion of the innate immune response may explain the failure of antimicrobial treatments in this patient. Copyright © 2016 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.
Comparison of Protein Extracts from Various Unicellular Green Sources

NARCIS (Netherlands)

Teuling, Emma; Wierenga, Peter A.; Schrama, Johan W.; Gruppen, Harry

2017-01-01

Photosynthetic unicellular organisms are considered as promising alternative protein sources. The aim of this study is to understand the extent to which these green sources differ with respect to their gross composition and how these differences affect the final protein isolate. Using mild isolation
Deep-well injection of liquid radioactive waste in Russia. Present situation

International Nuclear Information System (INIS)

Rybalchenko, A.

1998-01-01

At present there are 3 facilities (polygons) for the deep-well injection of liquid radioactive waste in Russia, all of which were constructed in the mid60's. These facilities are operating successfully, and activities have started in preparation for decommissioning. Liquid radioactive waste is injected into deep porous horizons which act as 'collector-layers', isolated from the surface and from groundwaters by a relatively thick sequence of rock of low permeability. The collector-layers (also collector-horizons) contain salt waters or fresh waters of no practical application, lying beneath the main horizons containing potable waters. Construction of facilities for the deep-well injection of liquid radioactive waste was preceded by geological surveys and investigations which were able to substantiate the feasibility and safety of radioactive waste injection, and to obtain initial data for facility design. Operation of the facilities was accompanied by monitoring which confirmed that the main safety requirement was satisfied i.e. localisation of radioactive waste within specified boundaries of the geologic medium. The opinion of most specialists in the atomic power industry in Russia favours deep-well injection as a solution to the problem of liquid radioactive waste management; during the period of active operation of defence facilities (atomic power industry of the former U.S.S.R.), this disposal method prevented the impact of radioactive waste on man and the environment. The experience accumulated concerning the injection of liquid radioactive waste in Russia is of interest to scientists and engineers engaged in problems of protection and remediation of the environment in the vicinity of nuclear industry facilities; an example of the utilisation of the deep subsurface for solidified radioactive waste and the disposal of different types of nuclear materials. Information on the scientific principles and background for the development of facilities for the injection
Properties of Laser-Produced Highly Charged Heavy Ions for Direct Injection Scheme

CERN Document Server

Sakakibara, Kazuhiko; Hayashizaki, Noriyosu; Ito, Taku; Kashiwagi, Hirotsugu; Okamura, Masahiro

2005-01-01

To accelerate highly charged intense ion beam, we have developed the Direct Plasma Injection Scheme (DPIS) with laser ion source. In this scheme an ion beam from a laser ion source is injected directly to a RFQ linac without a low energy beam transport (LEBT) and the beam loss in the LEBT can be avoided. We achieved high current acceleration of carbon ions (60mA) by DPIS with the high current optimized RFQ. As the next setp we will use heavier elements like Ag, Pb, Al and Cu as target in LIS (using CO2, Nd-YAG or other laser) for DPIS and will examine properties of laser-produced plasma (the relationship of between charge state and laser power density, the current dependence of the distance from the target, etc).
Isolation and screening of azo dye decolorizing bacterial isolates from dye-contaminated textile wastewater

Directory of Open Access Journals (Sweden)

Shahid Mahmood

2011-04-01

Full Text Available Azo dyes are released into wastewater streams without any pretreatment and pollute water and soilenvironments. To prevent contamination of our vulnerable resources, removal of these dye pollutants is of greatimportance. For this purpose, wastewater samples were collected from dye-contaminated sites of Faisalabad. About200 bacterial isolates were isolated through enrichment and then tested for their potential to remove RemazolBlack-B azo dye in liquid medium. Five bacterial isolates capable of degrading Remazol Black-B azo dye efficientlywere screened through experimentation on modified mineral salt medium. Isolate SS1 (collected from wastewater ofSupreme Textile Industry was able to completely remove the Remazol Black-B dye from the liquid medium in 18 h.Further, the isolate showed the best performance at the dye concentration of 100 mg L-1 medium (pH 7 and attemperature 35oC. Similarly, yeast extract proved to be the best carbon source for decolorization purpose. Theresults imply that the isolate SS1 could be used for the removal of the reactive dyes from textile effluents.
Anesthetic efficacy of a repeated intraosseous injection following a primary intraosseous injection.

Science.gov (United States)

Jensen, Joanne; Nusstein, John; Drum, Melissa; Reader, Al; Beck, Mike

2008-02-01

The purpose of this prospective, randomized, single-blinded study was to determine the anesthetic efficacy of a repeated intraosseous injection given 30 minutes after a primary intraosseous injection. Using a crossover design, 55 subjects randomly received a primary X-tip intraosseous injection (Dentsply Inc, York, PA) of 1.4 mL of 2% lidocaine with epinephrine (using the Wand; Milestone Scientific, Deerfield, IL) and a repeated intraosseous or mock injection at 30 minutes in two appointments. The first molar and adjacent teeth were pulp tested every 2 minutes for a total of 120 minutes. Success was defined as obtaining two consecutive 80 readings with the electric pulp tester. Success of the initial intraosseous injection was 100% for the first molar. The repeated intraosseous injection mimicked the initial intraosseous injection in terms of pulpal anesthesia and statistically provided another 15 minutes of pulpal anesthesia. In conclusion, using the methodology presented, repeating the intraosseous injection 30 minutes after an initial intraosseous injection will provide an additional 15 minutes of pulpal anesthesia.

Colistimethate Injection

Science.gov (United States)

... injection is in a class of medications called antibiotics. It works by killing bacteria.Antibiotics such as colistimethate injection will not work for colds, flu, or other viral infections. Using ...
Injection Laryngoplasty Materials

OpenAIRE

Haldun Oðuz

2013-01-01

Injection laryngoplasty is one of the treatment options for voice problems. In the recent years, more safe and more biocompatible injection materials are available on the market. Long and short term injection materials are discussed in this review.
Glenohumeral Joint Injections

Science.gov (United States)

Gross, Christopher; Dhawan, Aman; Harwood, Daniel; Gochanour, Eric; Romeo, Anthony

2013-01-01

Context: Intra-articular injections into the glenohumeral joint are commonly performed by musculoskeletal providers, including orthopaedic surgeons, family medicine physicians, rheumatologists, and physician assistants. Despite their frequent use, there is little guidance for injectable treatments to the glenohumeral joint for conditions such as osteoarthritis, adhesive capsulitis, and rheumatoid arthritis. Evidence Acquisition: We performed a comprehensive review of the available literature on glenohumeral injections to help clarify the current evidence-based practice and identify deficits in our understanding. We searched MEDLINE (1948 to December 2011 [week 1]) and EMBASE (1980 to 2011 [week 49]) using various permutations of intra-articular injections AND (corticosteroid OR hyaluronic acid) and (adhesive capsulitis OR arthritis). Results: We identified 1 and 7 studies that investigated intra-articular corticosteroid injections for the treatment of osteoarthritis and adhesive capsulitis, respectively. Two and 3 studies investigated the use of hyaluronic acid in osteoarthritis and adhesive capsulitis, respectively. One study compared corticosteroids and hyaluronic acid injections in the treatment of osteoarthritis, and another discussed adhesive capsulitis. Conclusion: Based on existing studies and their level of evidence, there is only expert opinion to guide corticosteroid injection for osteoarthritis as well as hyaluronic acid injection for osteoarthritis and adhesive capsulitis. PMID:24427384
AGS polarized H- source

International Nuclear Information System (INIS)

Kponou, A.; Alessi, J.G.; Sluyters, T.

1985-01-01

The AGS polarized H - source is now operational. During a month-long experimental physics run in July 1984, pulses equivalent to 15 μA x 300 μs (approx. 3 x 10 10 protons) were injected into the RFQ preaccelerator. Beam polarization, measured at 200 MeV, was approx. 75%. After the run, a program to increase the H - yield of the source was begun and significant progress has been made. The H - current is now frequently 20 to 30 μA. A description of the source and some details of our operating experience are given. We also briefly describe the improvement program
Injection Tests

CERN Document Server

Kain, V

2009-01-01

The success of the start-up of the LHC on 10th of September was in part due to the preparation without beam and injection tests in 2008. The injection tests allowed debugging and improvement in appropriate portions to allow safe, efficient and state-of-the-art commissioning later on. The usefulness of such an approach for a successful start-up becomes obvious when looking at the problems we encountered before and during the injection tests and could solve during this period. The outline of the preparation and highlights of the different injection tests will be presented and the excellent performance of many tools discussed. A list of shortcomings will follow, leading to some planning for the preparation of the run in 2009.
11. international conference on ion sources

International Nuclear Information System (INIS)

Leitner, D.; Lyneis, C.; Cheng, D.; Galloway, M.L.; Leitner, M.; Todd, D.S.; Ciavola, G.; Gammino, S.; Celona, L.; Ando, L.; Torrisi, L.; Cavenago, M.; Galata, A.; Spaedtke, P.; Tinschert, K.; Lang, R.; Iannucci, R.; Leroy, R.; Barue, C.; Hitz, D.; Koivisto, H.; Suominen, P.; Tarvainen, O.; Beijers, H.; Brandenburg, S.; Vanrooyen, D.; Hillo, C.; Kuchler, D.; Homeyer, H.; Rohrich, J.; Schachter, L.; Dobrescu, S.; Nakagawa, T.; Higurashi, Y.; Kidera, M.; Aihara, T.; Kase, M.; Goto, A.; Yang, Y.; Zhao, H.W.; Zhang, Z.M.; Zhang, X.Z.; Guo, X.H.; He, W.E.; Sun, L.T.; Yuan, P.; Song, M.T.; Xie, Z.Q.; Cao, Y.; Zhan, W.L.; Wei, B.W.; Bricault, P.; Lau, C.; Essabaa, S.; Cheikh Mhamed, M.; Bajeat, O.; Ducourtieux, M.; Lefort, H.; Panteleev, V.N.; Barzakh, A.E.; Fedorov, D.V.; Ionan, A.M.; Mezilev, K.A.; Moroz, F.V.; Orlov, S.Y.; Volkov, Y.M.; Andrighetto, A.; Lhersonneau, G.; Rizzi, V.; Tecchio, L.B.; Dubois, M.; Gaubert, G.; Jardins, P.; Lecesne, N.; Leroy, R.; Pacquet, J.Y.; Saint Laurent, M.G.; Villari, A.C.O.; Bajeat, O.; Essabaa, S.; Lau, C.; Menna, M.; Franberg, H.; Ammann, M.; Gdggeler, H.W.; Koster, U.; Allen, F.; Biedermann, C.; Radtke, R.; Ames, F.; Baartman, R.; Bricault, P.; Jayamanna, K.; Lamy, T.; McDonald, M.; Olivo, M.; Schmorl, P.; Yuan, D.H.L.; Asaji, T.; Sasaki, H.; Kato, Y.; Atabaev, B.; Radjabov, S.S.; Akhmadjanova, M.K.; Yuzikaeva, F.R.; Baoqun, Cui; Liqiang, Li; Yingjun, Ma; Shengyun, Zhu; Cong, Jiang

2005-01-01

This document gathers the summaries of the presentations made at ICIS05 (international conference on ion sources). It can be organized into 3 main topics: 1) 'fundamentals and theory' that deals with plasma, beam extraction, transport and emittance, diagnostics and simulation; 2) 'various types of ion sources' that include ECRIS, EBIS, microwave, negative, radioactive, polarized and laser ion sources, and charge breeders; and 3) 'ion sources and applications' in fields like accelerator injection, fusion energy, space propulsion, mass spectrometry, and neutron and cluster and rare nuclide production
[Investigation of neural stem cell-derived donor contribution in the inner ear following blastocyst injection].

Science.gov (United States)

Volkenstein, S; Brors, D; Hansen, S; Mlynski, R; Dinger, T C; Müller, A M; Dazert, S

2008-03-01

Utilising the enormous proliferation and multi-lineage differentiation potentials of somatic stem cells represents a possible therapeutical strategy for diseases of non-regenerative tissues like the inner ear. In the current study, the possibility of murine neural stem cells to contribute to the developing inner ear following blastocyst injection was investigated. Fetal brain-derived neural stem cells from the embryonic day 14 cortex of male mice were isolated and expanded for four weeks in neurobasal media supplemented with bFGF and EGF. Neural stem cells of male animals were harvested, injected into blastocysts and the blastocysts were transferred into pseudo-pregnant foster animals. Each blastocyst was injected with 5-15 microspheres growing from single cell suspension from neurospheres dissociated the day before. The resulting mice were investigated six months POST PARTUM for the presence of donor cells. Brainstem evoked response audiometry (BERA) was performed in six animals. To visualize donor cells Lac-Z staining was performed on sliced cochleas of two animals. In addition, the cochleas of four female animals were isolated and genomic DNA of the entire cochlea was analyzed for donor contribution by Y-chromosome-specific PCR. All animals had normal thresholds in brainstem evoked response audiometry. The male-specific PCR product indicating the presence of male donor cells were detected in the cochleas of three of the four female animals investigated. In two animals, male donor cells were detected unilateral, in one animal bilateral. The results suggest that descendants of neural stem cells are detectable in the inner ear after injection into blastocysts and possess the ability to integrate into the developing inner ear without obvious loss in hearing function.
A summary of the sources of input parameter values for the Waste Isolation Pilot Plant final porosity surface calculations

International Nuclear Information System (INIS)

Butcher, B.M.

1997-08-01

A summary of the input parameter values used in final predictions of closure and waste densification in the Waste Isolation Pilot Plant disposal room is presented, along with supporting references. These predictions are referred to as the final porosity surface data and will be used for WIPP performance calculations supporting the Compliance Certification Application to be submitted to the U.S. Environmental Protection Agency. The report includes tables and list all of the input parameter values, references citing their source, and in some cases references to more complete descriptions of considerations leading to the selection of values
A summary of the sources of input parameter values for the Waste Isolation Pilot Plant final porosity surface calculations

Energy Technology Data Exchange (ETDEWEB)

Butcher, B.M.

1997-08-01

A summary of the input parameter values used in final predictions of closure and waste densification in the Waste Isolation Pilot Plant disposal room is presented, along with supporting references. These predictions are referred to as the final porosity surface data and will be used for WIPP performance calculations supporting the Compliance Certification Application to be submitted to the U.S. Environmental Protection Agency. The report includes tables and list all of the input parameter values, references citing their source, and in some cases references to more complete descriptions of considerations leading to the selection of values.
Light Control of Insulin Release and Blood Glucose Using an Injectable Photoactivated Depot.

Science.gov (United States)

Sarode, Bhagyesh R; Kover, Karen; Tong, Pei Y; Zhang, Chaoying; Friedman, Simon H

2016-11-07

In this work we demonstrate that blood glucose can be controlled remotely through light stimulated release of insulin from an injected cutaneous depot. Human insulin was tethered to an insoluble but injectable polymer via a linker, which was based on the light cleavable di-methoxy nitrophenyl ethyl (DMNPE) group. This material was injected into the skin of streptozotocin-treated diabetic rats. We observed insulin being released into the bloodstream after a 2 min trans-cutaneous irradiation of this site by a compact LED light source. Control animals treated with the same material, but in which light was blocked from the site, showed no release of insulin into the bloodstream. We also demonstrate that additional pulses of light from the light source result in additional pulses of insulin being absorbed into circulation. A significant reduction in blood glucose was then observed. Together, these results demonstrate the feasibility of using light to allow for the continuously variable control of insulin release. This in turn has the potential to allow for the tight control of blood glucose without the invasiveness of insulin pumps and cannulas.
Injectable TEMPO-oxidized nanofibrillated cellulose/biphasic calcium phosphate hydrogel for bone regeneration.

Science.gov (United States)

Safwat, Engie; Hassan, Mohammad L; Saniour, Sayed; Zaki, Dalia Yehia; Eldeftar, Mervat; Saba, Dalia; Zazou, Mohamed

2018-05-01

Nanofibrillated cellulose, obtained from rice straw agricultural wastes was used as a substrate for the preparation of a new injectable and mineralized hydrogel for bone regeneration. Tetramethyl pyridine oxyl (TEMPO) oxidized nanofibrillated cellulose, was mineralized through the incorporation of a prepared and characterized biphasic calcium phosphate at a fixed ratio of 50 wt%. The TEMPO-oxidized rice straw nanofibrillated cellulose was characterized using transmission electron microscopy, Fourier transform infrared, and carboxylic content determination. The injectability and viscosity of the prepared hydrogel were evaluated using universal testing machine and rheometer testing, respectively. Cytotoxicity and alkaline phosphatase level tests on osteoblast like-cells for in vitro assessment of the biocompatibility were investigated. Results revealed that the isolated rice straw nanofibrillated cellulose is a nanocomposite of the cellulose nanofibers and silica nanoparticles. Rheological properties of the tested materials are suitable for use as injectable material and of nontoxic effect on osteoblast-like cells, as revealed by the positive alkaline phosphate assay. However, nanofibrillated cellulose/ biphasic calcium phosphate hydrogel showed higher cytotoxicity and lower bioactivity test results when compared to that of nanofibrillated cellulose.
Lessons Learned from Characterization, Performance Assessment, and EPA Regulatory Review of the 1996 Actinide Source Term for the Waste Isolation Pilot Plant

International Nuclear Information System (INIS)

Larson, K.W.; Moore, R.C.; Nowak, E.J.; Papenguth, H.W.; Jow, H.

1999-01-01

The Waste Isolation Pilot Plant (WIPP) is a US Department of Energy (DOE) facility for the permanent disposal of transuranic waste from defense activities. In 1996, the DOE submitted the Title 40 CFR Part 191 Compliance Certification Application for the Waste Isolation Pilot Plant (CCA) to the US Environmental Protection Agency (EPA). The CCA included a probabilistic performance assessment (PA) conducted by Sandia National Laboratories to establish compliance with the quantitative release limits defined in 40 CFR 191.13. An experimental program to collect data relevant to the actinide source term began around 1989, which eventually supported the 1996 CCA PA actinide source term model. The actinide source term provided an estimate of mobile dissolved and colloidal Pu, Am, U, Th, and Np concentrations in their stable oxidation states, and accounted for effects of uncertainty in the chemistry of brines in waste disposal areas. The experimental program and the actinide source term included in the CCA PA underwent EPA review lasting more than 1 year. Experiments were initially conducted to develop data relevant to the wide range of potential future conditions in waste disposal areas. Interim, preliminary performance assessments and actinide source term models provided insight allowing refinement of experiments and models. Expert peer review provided additional feedback and confidence in the evolving experimental program. By 1995, the chemical database and PA predictions of WIPP performance were considered reliable enough to support the decision to add an MgO backfill to waste rooms to control chemical conditions and reduce uncertainty in actinide concentrations, especially for Pu and Am. Important lessons learned through the characterization, PA modeling, and regulatory review of the actinide source term are (1) experimental characterization and PA should evolve together, with neither activity completely dominating the other, (2) the understanding of physical processes
Development of the TFTR neutral beam injection system

International Nuclear Information System (INIS)

Prichard, B.A. Jr.

1978-01-01

The TFTR Neutral Beam Lines are designed to inject 20 MW of 120 keV neutral deuterium atoms into the plasma. This is accomplished using 12 sources, 65 amperes each, mounted in 4 beam lines. The 120 kV sources are being developed by LBL and a prototype beam line which will be tested at Berkeley is being developed as a cooperative effort by LLL and LBL. The implementation of these beam lines has required the development of several associated pieces of hardware. The control and monitoring of the 12 sources will be done via the TFTR computer control system (CICADA) as will other parts of the machine, and software is being developed to condition and operate the sources automatically. The prototype beam line is scheduled to begin operation in the fall of 1978 and all four production beam lines on TFTR in 1982
Meropenem Injection

Science.gov (United States)

... injection is in a class of medications called antibiotics. It works by killing bacteria that cause infection.Antibiotics such as meropenem injection will not work for colds, flu, or other viral infections. Taking ...
Chloramphenicol Injection

Science.gov (United States)

... injection is in a class of medications called antibiotics. It works by stopping the growth of bacteria..Antibiotics such as chloramphenicol injection will not work for colds, flu, or other viral infections. Taking ...
Arthritis by autoreactive T cell lines obtained from rats after injection of intestinal bacterial cell wall fragments

NARCIS (Netherlands)

I. Klasen (Ina); J. Kool (Jeanette); M.J. Melief (Marie-José); I. Loeve (I.); W.B. van den Berg (Wim); A.J. Severijnen; M.P.H. Hazenberg (Maarten)

1992-01-01

markdownabstract__Abstract__ T cell lines (B13, B19) were isolated from the lymph nodes of Lewis rats 12 days after an arthritogenic injection of cell wall fragments of Eubacterium aerofaciens (ECW), a major resident of the human intestinal flora. These cell wall fragments consist of
Attack methodology Analysis: SQL Injection Attacks and Their Applicability to Control Systems

Energy Technology Data Exchange (ETDEWEB)

Bri Rolston

2005-09-01

Database applications have become a core component in control systems and their associated record keeping utilities. Traditional security models attempt to secure systems by isolating core software components and concentrating security efforts against threats specific to those computers or software components. Database security within control systems follows these models by using generally independent systems that rely on one another for proper functionality. The high level of reliance between the two systems creates an expanded threat surface. To understand the scope of a threat surface, all segments of the control system, with an emphasis on entry points, must be examined. The communication link between data and decision layers is the primary attack surface for SQL injection. This paper facilitates understanding what SQL injection is and why it is a significant threat to control system environments.
Worldwide Injection Technique Questionnaire Study: Population Parameters and Injection Practices.

Science.gov (United States)

Frid, Anders H; Hirsch, Laurence J; Menchior, Astrid R; Morel, Didier R; Strauss, Kenneth W

2016-09-01

From February 1, 2014, through June 30, 2015, 13,289 insulin-injecting patients from 423 centers in 42 countries took part in one of the largest surveys ever performed in diabetes. The goal was to assess patient characteristics, as well as historical and practical aspects of their injection technique. Results show that 4- and 8-mm needle lengths are each used by nearly 30% of patients and 5- and 6-mm needles each by approximately 20%. Higher consumption of insulin (as measured by total daily dose) is associated with having lipohypertrophy (LH), injecting into LH, leakage from the injection site, and failing to reconstitute cloudy insulin. Glycated hemoglobin values are, on average, 0.5% higher in patients with LH and are significantly higher with incorrect rotation of sites and with needle reuse. Glycated hemoglobin values are lower in patients who distribute their injections over larger injection areas and whose sites are inspected routinely. The frequencies of unexpected hypoglycemia and glucose variability are significantly higher in those with LH, those injecting into LH, those who incorrectly rotate sites, and those who reuse needles. Needles associated with diabetes treatment are the most commonly used medical sharps in the world. However, correct disposal of sharps after use is critically suboptimal. Many used sharps end up in public trash and constitute a major accidental needlestick risk. Use of these data should stimulate renewed interest in and commitment to optimizing injection practices in patients with diabetes. Copyright © 2016 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.
Granisetron Injection

Science.gov (United States)

Granisetron immediate-release injection is used to prevent nausea and vomiting caused by cancer chemotherapy and to ... nausea and vomiting that may occur after surgery. Granisetron extended-release (long-acting) injection is used with ...
Edaravone Injection

Science.gov (United States)

Edaravone injection is used to treat amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease; a condition in which ... die, causing the muscles to shrink and weaken). Edaravone injection is in a class of medications called ...

Defibrotide Injection

Science.gov (United States)

Defibrotide injection is used to treat adults and children with hepatic veno-occlusive disease (VOD; blocked blood ... the body and then returned to the body). Defibrotide injection is in a class of medications called ...
Nalbuphine Injection

Science.gov (United States)

... injection is in a class of medications called opioid agonist-antagonists. It works by changing the way ... suddenly stop using nalbuphine injection, you may experience withdrawal symptoms including restlessness; teary eyes; runny nose; yawning; ...
Study of the nonequilibrium state of superconductors by large quasiparticle injection from an external current source

International Nuclear Information System (INIS)

Iguchi, I.

1977-01-01

We have studied the nonequilibrium state of superconductors by injecting large numbers of quasiparticles from an external current source into a superconducting film of a tunnel junction with low tunnel resistance (typically 0.1--1 Ω for junction area approx. = 10 -4 cm 2 ). It was observed that there was a critical tunnel current density at which a voltage appeared locally in the part of a superconducting film confined to the junction area. Its values ranged from 10 2 to 10 3 A/cm 2 for bath temperatures well below T/sub c/. Followed by this voltage onset, a transition region corresponding to the nonequilibrium intermediate resistive state was also observed. For further increase of the tunnel current, the local film resistance developed beyond the value of its normal resistance, suggesting that the nonequilibrium state extends far beyond the voltage onset point. A theory based on the modified Rothwarf-Taylor equations and Parker's T* model is presented to compare with the experimental results. The calculated critical current density yielded almost the same order of magnitude as those found experimentally. The detailed behavior, however, deviates from the theoretical predictions although the film makes a second-order transition in the broad range of temperatures. It is also shown using four-terminal analysis that our observations and those by Wong, Yeh, and Langenberg are essentially the same
External injection systems applied in modern cyclotrons designed and manufactured in NIIEFA

International Nuclear Information System (INIS)

Bogdanov, P.V.; Vasilchenko, I.N.; Veresov, O.L.; Gavrish, Yu.N.; Grigorenko, S.V.; Zuev, Yu.V.; Kozienko, M.T.; Mudrolyubov, V.G.; Strokach, A.P.; Tsygankov, S.S.

2012-01-01

The main parameters and design features of the external injection systems applied in modern cyclotrons designed and manufactured in NIIEFA and intended for production of radionuclides for medicine are presented. The use of these external injection systems instead of a traditional internal source allows the current of the accelerated beam to be significantly increased and the in-leakage of the working gas to the acceleration chamber to be reduced, which results in reduced beam losses in the process of acceleration and lower equipment activation.
BWR fuel experience with zinc injection

International Nuclear Information System (INIS)

Levin, H.A.; Garcia, S.E.

1995-01-01

In 1982 a correlation between low primary recirculation system dose rates in BWR's and the presence of ionic zinc in reactor water was identified. The source of the zinc was primarily from Admiralty brass condensers. Plants with brass condensers are called ''natural zinc'' plants. Brass condensers were also a source of copper that was implicated in crude induced localized corrosion (CILC) fuel failures. In 1986 the first BWR intentionally injected zinc for the benefits of dose rate control. Although zinc alone was never implicated in fuel degradation of failures, a comprehensive fuel surveillance program was initiated to monitor fuel performance. Currently there are 14 plants that are injecting zinc. Six of these plants are also on hydrogen water chemistry. This paper describes the effect on both Zircaloy corrosion and the cruding characteristics as a result of these changes in water chemistry. Fuel rod corrosion was found to be independent of the specific water chemistry of the plants. The corrosion behavior was the same with the additions of zinc alone or zinc plus hydrogen and well within the operating experience for fuel without either of these additions. No change was observed in the amounts of crude deposited on the fuel rods, both for the adherent and loosely held deposits. One of the effects of the zinc addition was the trend to form more of the zinc rich iron spinel in the fuel deposits rather than the hematite deposits that are predominantly formed with non additive water chemistry
Two Component Injection Moulding for Moulded Interconnect Devices

DEFF Research Database (Denmark)

Islam, Aminul

component (2k) injection moulding is one of the most industrially adaptive processes. However, the use of two component injection moulding for MID fabrication, with circuit patterns in sub-millimeter range, is still a big challenge. This book searches for the technical difficulties associated...... with the process and makes attempts to overcome those challenges. In search of suitable polymer materials for MID applications, potential materials are characterized in terms of polymer-polymer bond strength, polymer-polymer interface quality and selective metallization. The experimental results find the factors...... which can effectively control the quality of 2k moulded parts and metallized MIDs. This book presents documented knowledge about MID process chains, 2k moulding and selective metallization which can be valuable source of information for both academic and industrial users....
Electron beam injection during active experiments. I - Electromagnetic wave emissions

Science.gov (United States)

Winglee, R. M.; Kellogg, P. J.

1990-01-01

The wave emissions produced in Echo 7 experiment by active injections of electron beams were investigated to determine the properties of the electromagnetic and electrostatic fields for both the field-aligned and cross-field injection in such experiments and to evaluate the sources of free energy and relative efficiencies for the generation of the VLF and HF emissions. It is shown that, for typical beam energies in active experiments, electromagnetic effects do not substantially change the bulk properties of the beam, spacecraft charging, and plasma particle acceleration. Through simulations, beam-generated whistlers; fundamental z-mode and harmonic x-mode radiation; and electrostatic electron-cyclotron, upper-hybrid, Langmuir, and lower-hybrid waves were identified. The characteristics of the observed wave spectra were found to be sensitive to both the ratio of the electron plasma frequency to the cyclotron frequency and the angle of injection relative to the magnetic field.
Piezoelectric Injection Systems

Science.gov (United States)

Mock, R.; Lubitz, K.

The origin of direct injection can be doubtlessly attributed to Rudolf Diesel who used air assisted injection for fuel atomisation in his first self-ignition engine. Although it became apparent already at that time that direct injection leads to reduced specific fuel consumption compared to other methods of fuel injection, it was not used in passenger cars for the moment because of its disadvantageous noise generation as the requirements with regard to comfort were seen as more important than a reduced specific consumption.
11. international conference on ion sources

Energy Technology Data Exchange (ETDEWEB)

Leitner, D.; Lyneis, C.; Cheng, D.; Galloway, M.L.; Leitner, M.; Todd, D.S.; Ciavola, G.; Gammino, S.; Celona, L.; Ando, L.; Torrisi, L.; Cavenago, M.; Galata, A.; Spaedtke, P.; Tinschert, K.; Lang, R.; Iannucci, R.; Leroy, R.; Barue, C.; Hitz, D.; Koivisto, H.; Suominen, P.; Tarvainen, O.; Beijers, H.; Brandenburg, S.; Vanrooyen, D.; Hillo, C.; Kuchler, D.; Homeyer, H.; Rohrich, J.; Schachter, L.; Dobrescu, S.; Nakagawa, T.; Higurashi, Y.; Kidera, M.; Aihara, T.; Kase, M.; Goto, A.; Yang, Y.; Zhao, H.W.; Zhang, Z.M.; Zhang, X.Z.; Guo, X.H.; He, W.E.; Sun, L.T.; Yuan, P.; Song, M.T.; Xie, Z.Q.; Cao, Y.; Zhan, W.L.; Wei, B.W.; Bricault, P.; Lau, C.; Essabaa, S.; Cheikh Mhamed, M.; Bajeat, O.; Ducourtieux, M.; Lefort, H.; Panteleev, V.N.; Barzakh, A.E.; Fedorov, D.V.; Ionan, A.M.; Mezilev, K.A.; Moroz, F.V.; Orlov, S.Y.; Volkov, Y.M.; Andrighetto, A.; Lhersonneau, G.; Rizzi, V.; Tecchio, L.B.; Dubois, M.; Gaubert, G.; Jardins, P.; Lecesne, N.; Leroy, R.; Pacquet, J.Y.; Saint Laurent, M.G.; Villari, A.C.O.; Bajeat, O.; Essabaa, S.; Lau, C.; Menna, M.; Franberg, H.; Ammann, M.; Gdggeler, H.W.; Koster, U.; Allen, F.; Biedermann, C.; Radtke, R.; Ames, F.; Baartman, R.; Bricault, P.; Jayamanna, K.; Lamy, T.; McDonald, M.; Olivo, M.; Schmorl, P.; Yuan, D.H.L.; Asaji, T.; Sasaki, H.; Kato, Y.; Atabaev, B.; Radjabov, S.S.; Akhmadjanova, M.K.; Yuzikaeva, F.R.; Baoqun, Cui; Liqiang, Li; Yingjun, Ma; Shengyun, Zhu; Cong, Jiang

2005-07-01

This document gathers the summaries of the presentations made at ICIS05 (international conference on ion sources). It can be organized into 3 main topics: 1) 'fundamentals and theory' that deals with plasma, beam extraction, transport and emittance, diagnostics and simulation; 2) 'various types of ion sources' that include ECRIS, EBIS, microwave, negative, radioactive, polarized and laser ion sources, and charge breeders; and 3) 'ion sources and applications' in fields like accelerator injection, fusion energy, space propulsion, mass spectrometry, and neutron and cluster and rare nuclide production.
Effect of injection energy on residual dose around the charge exchange foil

Directory of Open Access Journals (Sweden)

Kazami Yamamoto

2012-12-01

Full Text Available The rapid cycling synchrotron (RCS of Japan Proton Accelerator Research Complex (J-PARC and the accumulator ring (AR of Spallation Neutron Source (SNS can be used as high-power pulsed neutron sources. In both cases, the injection region becomes one of the highest activation areas in the ring. However, residual dose distributions have revealed that the highest activation points in the J-PARC RCS and the SNS AR are different in detail. The dose of the charge exchange chamber in the SNS is more than 100 times larger than that of the RCS though the ratio of beam power is less than 10. We investigated the reason of this difference by Geant4 and MARS, and the calculation results indicated that the difference was due to the dependence of the neutron and pion production rate on the injection energy.
Molecular epidemiology of nontuberculous mycobacteria isolates from clinical and environmental sources of a metropolitan city.

Directory of Open Access Journals (Sweden)

Ali Akbar Velayati

Full Text Available While NTM infection is mainly acquired from environmental exposure, monitoring of environmental niches for NTM is not a routine practice. This study aimed to find the prevalence of environmental NTM in soil and water in four highly populated suburbs of Tehran, Iran.A total of 4014 samples from soil and water resources were collected and studied. Sediments of each treated sample were cultured in Lowenstein-Jensen medium and observed twice per week for growth rate, colony morphology, and pigmentation. Colonies were studied with phenotypic tests. Molecular analysis was performed on single colonies derived from subculture of original isolates. Environmental samples were compared with 34 NTM isolates from patients who were residents of the study locations.Out of 4014 samples, mycobacteria were isolated from 862 (21.4% specimens; 536 (62.1% belonged to slow growing mycobacteria (SGM and 326 (37.8% were rapid growing mycobacteria (RGM. The five most frequent NTM were M. farcinogens (105/862; 12.1%, M. fortuitum (72/862; 8.3%, M. senegalense (58/862; 6.7%, M. kansasii (54/862; 6.2%, and M. simiae (46/862; 5.3%. In total, 62.5% (539/862 of mycobacterial positive samples were isolated from water and only 37.4% (323/862 of them were isolated from soil samples (P<0.05. Out of 5314 positive clinical samples for mycobacteria, 175 (3.2% isolates were NTM. The trend of NTM isolates increased from 1.2% (13 out of 1078 in 2004 to 3.8% (39 out of 1005 in 2014 (P = 0.0001. The major clinical isolates were M. simiae (51; 29.1%, M. kansasii (26; 14.8%, M. chelonae (28; 16%, and M. fortuitum (13; 7.4%.Comparing the distribution pattern of environmental NTM isolates with clinical isolates suggests a possible transmission link, but this does not apply to all environmental NTM species. Our study confirms an increasing trend of NTM isolation from clinical samples that needs further investigation.
A comparison of molding procedures - Contact, injection and vacuum injection

Science.gov (United States)

Cathiard, G.

1980-06-01

The technical and economic aspects of the contact, injection and vacuum injection molding of reinforced plastic components are compared for the example of a tractor roof with a gel-coated surface. Consideration is given to the possibility of reinforcement, number of smooth faces, condition of the gel-coated surface, reliability, and labor and workplace requirements of the three processes, and advantages of molding between the mold and a countermold in smooth faces, reliability, labor requirements, working surface and industrial hygiene are pointed out. The times and labor requirements of each step in the molding cycles are examined, and material requirements and yields, investment costs, amortization and product cost prices of the processes are compared. It is concluded that, for the specific component examined, the processes of vacuum injection and injection molding appear very interesting, with injection molding processes resulting in lower cost prices than contact molding for any production volume.
Ion source requirements for pulsed spallation neutron sources

International Nuclear Information System (INIS)

Alonso, J.R.

1995-10-01

The neutron scattering community has endorsed the need for a high- power (1 to 5 MW) accelerator-driven source of neutrons for materials research. Properly configured, the accelerator could produce very short (sub-microsecond) bursts of cold neutrons, said time structure offering advantages over the continuous flux from a reactor for a large class of experiments. The recent cancellation of the ANS reactor project has increased the urgency to develop a comprehensive strategy based on the best technological scenarios. Studies to date have built on the experience from ISIS (the 160 KW source in the UK), and call for a high-current (approx. 100 mA peak) H - source-linac combination injecting into one or more accumulator rings in which beam may be further accelerated. The 1 to 5 GeV proton beam is extracted in a single turn and brought to the target-moderator stations. The high current, high duty-factor, high brightness and high reliability required of the ion source present a very large challenge to the ion source community. A workshop held in Berkeley in October 1994, analyzed in detail the source requirements for proposed accelerator scenarios, the present performance capabilities of different H - source technologies, and identified necessary R ampersand D efforts to bridge the gap
Prevalence of injections and knowledge of safe injections among rural residents in Central China.

Science.gov (United States)

Yan, Y W; Yan, J; Zhang, G P; Gao, Z L; Jian, H X

2007-08-01

Abuse of the injection services, namely unnecessary injections and unsafe injections, exists extensively in developing countries. Unsafe injection practices contribute to the transmission of blood-borne pathogens. The aims of this study were to survey the prevalence of injections and knowledge of injection safety among the rural residents in Jingzhou district, Hubei, China and to provide scientific data for developing a health educational programme. A retrospective cross-sectional study was conducted in 12 villages, which were selected from the Jingzhou district by the random sampling method. 50 rural residents were interviewed per village using a questionnaire. Among the 595 residents studied, 192 had received at least one injection in the past three months, with an injection prevalence of 32.3 percent and an average of 0.93 injections. 90.3 percent of the rural residents knew that unsafe injections could transmit the following blood-borne pathogens: human immunodeficiency virus (74.4 percent), hepatitis B virus (55.8 percent) and hepatitis C virus (22.9 percent). Logistic regression analysis showed that the residents' age, educational level and residential area were important factors in influencing their knowledge about injection safety. The results indicated that the injection prevalence was high among rural residents in the study area, and their knowledge regarding injection safety should be further improved.
Recent advances in micro-vibration isolation

Science.gov (United States)

Liu, Chunchuan; Jing, Xingjian; Daley, Steve; Li, Fengming

2015-05-01

Micro-vibration caused by disturbance sources onboard spacecraft can severely degrade the working environment of sensitive payloads. Some notable vibration control methods have been developed particularly for the suppression or isolation of micro-vibration over recent decades. Usually, passive isolation techniques are deployed in aerospace engineering. Active isolators, however, are often proposed to deal with the low frequency vibration that is common in spacecraft. Active/passive hybrid isolation has also been effectively used in some spacecraft structures for a number of years. In semi-active isolation systems, the inherent structural performance can be adjusted to deal with variation in the aerospace environment. This latter approach is potentially one of the most practical isolation techniques for micro-vibration isolation tasks. Some emerging advanced vibration isolation methods that exploit the benefits of nonlinearity have also been reported in the literature. This represents an interesting and highly promising approach for solving some challenging problems in the area. This paper serves as a state-of-the-art review of the vibration isolation theory and/or methods which were developed, mainly over the last decade, specifically for or potentially could be used for, micro-vibration control.
Residues and duality for singularity categories of isolated Gorenstein singularities

OpenAIRE

Murfet, Daniel

2009-01-01

We study Serre duality in the singularity category of an isolated Gorenstein singularity and find an explicit formula for the duality pairing in terms of generalised fractions and residues. For hypersurfaces we recover the residue formula of the string theorists Kapustin and Li. These results are obtained from an explicit construction of complete injective resolutions of maximal Cohen-Macaulay modules.
Injection-controlled laser resonator

Science.gov (United States)

Chang, J.J.

1995-07-18

A new injection-controlled laser resonator incorporates self-filtering and self-imaging characteristics with an efficient injection scheme. A low-divergence laser signal is injected into the resonator, which enables the injection signal to be converted to the desired resonator modes before the main laser pulse starts. This injection technique and resonator design enable the laser cavity to improve the quality of the injection signal through self-filtering before the main laser pulse starts. The self-imaging property of the present resonator reduces the cavity induced diffraction effects and, in turn, improves the laser beam quality. 5 figs.
Physics of Plasma Cathode Current Injection During LHI

Science.gov (United States)

Hinson, E. T.; Barr, J.; Bongard, M.; Burke, M. G.; Fonck, R.; Perry, J.

2015-11-01

Localized helicity injection (LHI) ST startup employs current sources at the tokamak edge. Max Ip in LHI scales with injection voltage Vinj, requiring an understanding of injector impedance. For the arc-plasma cathode electron injectors in Pegasus, impedance is plasma-determined, and typically Vinj>1kV for Iinj = 2kA. At low Iinj, Iinj Vinj3 / 2 , an indication of a double layer (DL) common to such devices. However, at Iinj> 1kA, Iinj Vinj1 / 2 occurs, a scaling expected for limited launched beam density, nb ≡Iinj / (e√{ 2eVinj /me }Ainj) Iinj /Vinj1 / 2 . An ohmic discharge injection target was created to test this hypothesis. Langmuir probe data showed Iinj/Vinj1 / 2 nedge at low nedge, consistent with a limit (nedge >=ne , b) imposed by quasineutrality. If edge fueling maintained nedge >=ne , b , spectroscopic measurements of source density narc indicated Iinj/Vinj1 / 2 narc , as expected from DL expansion. Thus nb established by narc or nedge determines Vinj up to the onset of cathode spot (CS) arcing. Technology development has increased obtainable Vinj and reduced CS damage using new ring shielding and a cathode design drawing CS's away from insulators. This involved a novel optimization of conical frustum geometry. Finally, consistent with NIMROD predictions of coherent streams in the edge during LHI, pairwise triangulation of outboard Mirnov data assuming beam m =1 motion has allowed an estimate of beam R(t), Z(t) location that is near the injector R, and consistent across the array. Supported by U.S. DOE Grant DE-FG02-96ER54375.
Electron cyclotron resonance (ECR) ion sources

International Nuclear Information System (INIS)

Jongen, Y.

1984-05-01

Starting with the pioneering work of R. Geller and his group in Grenoble (France), at least 14 ECR sources have been built and tested during the last five years. Most of those sources have been extremely successful, providing intense, stable and reliable beams of highly charged ions for cyclotron injection or atomic physics research. However, some of the operational features of those sources disagreed with commonly accepted theories on ECR source operation. To explain the observed behavior of actual sources, it was found necessary to refine some of the crude ideas we had about ECR sources. Some of those new propositions are explained, and used to make some extrapolations on the possible future developments in ECR sources
Background gas density and beam losses in NIO1 beam source

Energy Technology Data Exchange (ETDEWEB)

Sartori, E., E-mail: emanuele.sartori@igi.cnr.it; Veltri, P.; Serianni, G. [Consorzio RFX (CNR, ENEA, INFN, Università di Padova, Acciaierie Venete SpA), C.so Stati Uniti 4, 35127 Padova (Italy); Cavenago, M. [INFN-LNL, v.le dell’Università 2, I-35020 Legnaro (PD) (Italy)

2016-02-15

NIO1 (Negative Ion Optimization 1) is a versatile ion source designed to study the physics of production and acceleration of H- beams up to 60 keV. In ion sources, the gas is steadily injected in the plasma source to sustain the discharge, while high vacuum is maintained by a dedicated pumping system located in the vessel. In this paper, the three dimensional gas flow in NIO1 is studied in the molecular flow regime by the Avocado code. The analysis of the gas density profile along the accelerator considers the influence of effective gas temperature in the source, of the gas temperature accommodation by collisions at walls, and of the gas particle mass. The calculated source and vessel pressures are compared with experimental measurements in NIO1 during steady gas injection.

ECR ion source with electron gun

Science.gov (United States)

Xie, Zu Q.; Lyneis, Claude M.

1993-01-01

An Advanced Electron Cyclotron Resonance ion source (10) having an electron gun (52) for introducing electrons into the plasma chamber (18) of the ion source (10). The ion source (10) has a injection enclosure (12) and a plasma chamber tank (14). The plasma chamber (18) is defined by a plurality of longitudinal magnets (16). The electron gun (52) injects electrons axially into the plasma chamber (18) such that ionization within the plasma chamber (18) occurs in the presence of the additional electrons produced by the electron gun (52). The electron gun (52) has a cathode (116) for emitting electrons therefrom which is heated by current supplied from an AC power supply (96) while bias potential is provided by a bias power supply (118). A concentric inner conductor (60) and Outer conductor (62) carry heating current to a carbon chuck (104) and carbon pusher (114) Which hold the cathode (116) in place and also heat the cathode (16). In the Advanced Electron Cyclotron Resonance ion source (10), the electron gun (52) replaces the conventional first stage used in prior art electron cyclotron resonance ion generators.
Development of multiampere negative ion sources

International Nuclear Information System (INIS)

Alessi, J.; Hershcovitch, A.; Prelec, K.; Sluyters, T.

1981-01-01

The Neutral Beam Development Group at BNL is developing H-/D- surface plasma sources as part of a high energy neutral beam injector. Uncooled Penning and magnetron sources have operated at a maximum beam current of 1 A (10 ms pulses, Mk III) and a maximum pulse length of 200 ms (0.3 A, Mk IV). A magnetron source with focusing grooves on the cathode and an asymmetric anode-cathode geometry operates at a power efficiency of 8 kW/A and a 6% gas efficiency. As the next step, a water cooled magnetron, designed to give a steady state beam of 1 to 2 A, has been constructed. Experiments are in progress to test a modification of the magnetron which may significantly improve its performance. By injecting a sheet of plasma, produced by a highly gas efficient hollow cathode discharge, into a magnetron type anode-cathode geometry, we anticipate a reduction of the source operating pressure by at least three orders of magnitude. Initial experiments have given indications of H - production. The next plasma injection experiment is designed to give a steady state beam of approx. = 1 A
CT-guided cervical nerve root injections: comparing the immediate post-injection anesthetic-related effects of the transforaminal injection with a new indirect technique

International Nuclear Information System (INIS)

Sutter, Reto; Pfirrmann, Christian W.A.; Peterson, Cynthia K.; Zanetti, Marco; Hodler, Juerg

2011-01-01

To describe an ''indirect'' cervical nerve root injection technique with a dorsal approach that should carry less inherent risk than the ''direct'' cervical transforaminal injection approach, and to compare the immediate post-injection results of the two procedures. The indirect and direct cervical nerve root injection procedures are described in detail. Fifty-three consecutive patients receiving the indirect nerve root injections during 2009-2010 were age- and gender-matched to 53 patients who underwent direct transforaminal nerve root injections performed in 2006. Pain level data were collected immediately before and 20-30 min after each procedure. The percentages of pain change in the two groups were compared using the unpaired Student's t test. Fifty-two men (mean age 49) and 54 women (mean age 55) were included. The mean percentage of pain reduction for patients receiving indirect nerve root injections was 38.4% and for those undergoing the direct nerve root injections approach it was 43.2%. This was not significantly different (P = 0.455). No immediate or late adverse effects were reported after either injection procedure. The indirect cervical nerve root injection procedure is a potentially safer alternative to direct cervical transforaminal nerve root injections. The short-term pain reduction is similar using the two injection methods. (orig.)
Intraarticular cortisone injection for osteoarthritis of the hip. Is it effective? Is it safe?

OpenAIRE

Kruse, David W.

2008-01-01

Osteoarthritis of the hip is a significant source of morbidity in the elderly. Treatment guidelines are available for the management of hip osteoarthritis, but these do not address the application of intraarticular corticosteroid injection. The intraarticular injection of corticosteroid is used in the management of other large joint osteoarthritic diseases and is well studied in the knee, however, this data cannot be used to make sound clinical decisions regarding its use for hip osteoarthrit...
Vacuum Arc Ion Sources

CERN Document Server

Brown, I.

2013-12-16

The vacuum arc ion source has evolved into a more or less standard laboratory tool for the production of high-current beams of metal ions, and is now used in a number of different embodiments at many laboratories around the world. Applications include primarily ion implantation for material surface modification research, and good performance has been obtained for the injection of high-current beams of heavy-metal ions, in particular uranium, into particle accelerators. As the use of the source has grown, so also have the operational characteristics been improved in a variety of different ways. Here we review the principles, design, and performance of vacuum arc ion sources.
Monitoring of density in tokamaks: pumping and gas injection

International Nuclear Information System (INIS)

Dejarnac, R.

2002-11-01

In thermonuclear fusion devices, controlling the Deuterium-Tritium fuel density and exhausting the Helium ashes is a crucial point. This is achieved by fuelling the discharges by different methods (gas puffing and pellet injection are the most commonly used) and by implementing pumping devices at the plasma periphery. These two issues are treated in this work, both from an experimental and a modelling point of view, using the neutral transport code EIRENE as main tool for our studies. As far as pumping is concerned, we have modelled the outboard pump limiter of the Tore Supra tokamak with the EIRENE code to which we coupled a plasma module specially developed to simulate the neutrals and the plasma in a coherent way. This allowed to validate the code against experimental data. As far as plasma fuelling is concerned, we present here an original method: the supersonic pulsed gas injection (SPGI). This intermediate method between conventional gas puff (GP) and pellet injection was designed and tested at Tore Supra. It consists of injecting very dense and short gas puffs at high speed into the plasma. Experimentally, SPGI was found to have a better fuelling efficiency than GP and to lead to a strong plasma cooling. The mechanisms responsible for this improved efficiency are analysed by modelling, using the EIRENE code to determine the ionisation source and a 1 D transport model to reproduce the plasma density response. At last, an extrapolation of the present injector is presented, discussing the possibility to obtain a radial drift of the injected matter as observed in the case of high field side pellet injection. (author)
Lance water injection tests adjacent to the 281-3H retention basin at the Savannah River Site, Aiken, South Carolina

International Nuclear Information System (INIS)

Freifeld, B.; Myer, L.; Moridis, G.; Cook, P.; James, A.; Pellerin, L.; Pruess, K.

1996-09-01

A pilot-scale field demonstration of waste isolation using viscous- liquid containment barriers has been planned for the 281-3H retention basin at the Savannah River Site, Aiken, SC. The 281-3H basin is a shallow retention/seepage basin contaminated mainly by radionuclides. The viscous-liquid containment barrier utilizes the permeation of liquid grout to either entomb the contaminants within a monolithic grout structure or to isolate the waste by drastically reducing the permeability, of the soils around the plume. A clear understanding of the hydrogeologic setting of the retention basin is necessary for proper design of the viscous liquid barrier. To aid in the understanding of the hydrogeology of the 281-3H retention basin, and to obtain critical parameters necessary for grout injection design, a series of tests were undertaken in a region immediately adjacent to the basin. The objectives of the LWIT were: 1. To evaluate the general performance of the Lance Injection Technique for grout emplacement at the site, including the range and upper limits of injection pressures, the flow rates applicable for site conditions, as well as the mechanical forces needed for lance penetration. 2. To obtain detailed information on the injectability of the soils immediately adjacent to the H-area retention basin. 3. To identify any high permeability zones suitable for injection and evaluate their spatial distribution. 4. To perform ground penetrating radar (GPR) to gain information on the structure of the soil column and to compare the results with LWIT data. This report will focus on results pertinent to these objectives
A 14-MeV beam-plasma neutron source for materials testing

International Nuclear Information System (INIS)

Futch, A.H.; Coensgen, F.H.; Damm, C.C.; Molvik, A.W.

1989-01-01

The design and performance of 14-MeV beam-plasma neutron sources for accelerated testing of fusion reactor materials are described. Continuous production of 14-MeV neutron fluxes in the range of 5 to 10 MW/m 2 at the plasma surface are produced by D-T reactions in a two-component plasma. In the present designs, 14-MeV neutrons result from collisions of energetic deuterium ions created by transverse injection of 150-keV deuterium atoms on a fully ionized tritium target plasma. The beam energy, which deposited at the center of the tritium column, is transferred to the warm plasma by electron drag, which flows axially to the end regions. Neutral gas at high pressure absorbs the energy in the tritium plasma and transfers the heat to the walls of the vacuum vessel. The plasma parameters of the neutron source, in dimensionless units, have been achieved in the 2XIIB high-β plasma. The larger magnetic field of the present design permits scaling to the higher energy and density of the neutron source design. In the extrapolation, care has been taken to preserve the scaling and plasma attributes that contributed to equilibrium, magnetohydrodynamic (MHD) stability, and microstability in 2XIIB. The performance and scaling characteristics are described for several designs chosen to enhance the thermal isolation of the two-component plasmas. 11 refs., 3 figs., 3 tabs
Study of axial injection of polarized protons into the grenoble cyclotron

International Nuclear Information System (INIS)

Pabot, J.

1969-01-01

By injecting ions axially into a cyclotron, it is possible to accelerate particles (polarized particles, heavy ions, etc...) obtainable only with difficulty when an internal ion source is used. In this work, after justifying the choice of an axial injection device equipped with a 'pseudo-cylindrical' deflector for the Grenoble cyclotron, we study theoretically the principle of such a detector, the choice of its parameters, and the effect of this choice on the conditions of acceleration of the beam by the cyclotron. From the experimental point of view, this report describes two operations which made it possible to check that the chosen injection device operated satisfactorily, qualitatively initially (electron model), then quantitatively (proton model). In conclusion, we believe that the Grenoble cyclotron thus equipped will be able to provide a relatively dense beam of polarized protons. (author) [fr
Legal syringe purchases by injection drug users, Brooklyn and Queens, New York City, 2000-2001.

Science.gov (United States)

Des Jarlais, Don C; McKnight, Courtney; Friedmann, Patricia

2002-01-01

To assess preliminary results of the Expanded Syringe Access Demonstration Program (ESAP) in New York City. Temporal trends of pharmacy use among injection drug users (IDUs) in Brooklyn and Queens were analyzed from December 2000 through December 2001. Brooklyn and Queens, New York City. PARTIPANTS: IDUs. Attempts to purchase syringes from pharmacies and success in doing so. Of the 1,072 IDUs interviewed from December 2000 through December 2001, the majority were daily heroin injectors, but there was also substantial speedball and cocaine injection. There was a clear increase over time in both the percentage of subjects who attempted to purchase syringes in pharmacies and in the percentage who successfully purchased syringes. Among IDUs interviewed 4 or more months after ESAP began, large majorities of those who attempted to purchase syringes were successful in doing so. No differences in use of ESAP by IDUs were identified in Brooklyn versus Queens: 27% of IDUs interviewed in Queens reported that they had attempted to purchase syringes in pharmacies versus 28% in Brooklyn. Persons who reported injecting on a daily or more frequent basis were more likely to have attempted pharmacy purchases than persons who reported injecting less frequently, 32% versus 21%. The ESAP program has led to an increase in the use of pharmacies as sources of sterile injection equipment among IDUs in New York City. The extent to which pharmacies become an important source of sterile injection equipment and the effect of legal pharmacy sales on risk behaviors for human immunodeficiency virus (HIV) infection remain to be determined.
Optimization of injection law for direct injection diesel engine

International Nuclear Information System (INIS)

Feola, M.; Bella, G.; Pelloni, P.; Casoli, P.; Toderi, G.; Cantore, G.

1992-01-01

This paper describes how different timing and shape of the injection law can influence pollutant emission of a direct injection diesel engine. The study was carried out making use of a multizone thermodynamic model as regards the closed valve phase, and a filling-emptying one as regards the open valve phase. After being calibrated by comparison with experimental data, the abovementioned model was used for injection law optimization as regards minimum pollutant concentration (NO x and soot) in the exhaust gases with the smallest engine performance reduction possible
Broiler chickens, broiler chicken meat, pigs and pork as sources of ExPEC related virulence genes and resistance in Escherichia coli isolates from community-dwelling humans and UTI patients.

Science.gov (United States)

Jakobsen, Lotte; Spangholm, Daniel J; Pedersen, Karl; Jensen, Lars B; Emborg, Hanne-Dorthe; Agersø, Yvonne; Aarestrup, Frank M; Hammerum, Anette M; Frimodt-Møller, Niels

2010-08-15

Urinary tract infection (UTI) is one of the most common bacterial infections. UTI is primarily caused by extraintestinal pathogenic Escherichia coli (ExPEC) from the patients' own fecal flora. The ExPEC often belong to phylogroups B2 and D, the groups which include potent human ExPEC isolates causing UTI, bacteremia, and meningitis. The external sources of these ExPEC in the human intestine are unknown. The food supply may transmit ExPEC to humans. However, evidence of this hypothesis is limited. To assess this hypothesis, the objective of our study was to investigate the presence of ExPEC related virulence genes in E. coli isolates from UTI patients, community-dwelling humans, meat, and production animals. Accordingly, we included 964 geographically and temporally matched E. coli isolates from UTI patients (n=102), community-dwelling humans (n=109), fresh Danish (n=197) and imported broiler chicken meat (n=86), broiler chickens (n=138), fresh Danish (n=177) and imported pork (n=10), and pigs (n=145) in the study. All isolates were investigated for the presence of eight ExPEC related genes (kpsM II, papA, papC, iutA, sfaS, focG, afa, hlyD) using PCR. To investigate any similarities between isolates from the different origins, we performed a cluster analysis including antimicrobial resistance data previously published. We detected seven of the eight ExPEC related genes in isolates from broiler chicken meat, broiler chickens, pork and pigs. Our findings suggest that broiler chicken meat, broiler chickens, pork and pigs could be the source of strains with these ExPEC related virulence genes in community-dwelling humans and UTI patients. Especially detection of ExPEC related virulence genes in isolates belonging to phylogroups B2 and D is very concerning and may have a significant medical impact. The cluster analysis of virulence gene and antimicrobial resistance profiles showed strong similarities between UTI patient, community-dwelling human isolates, meat, and
BEPC II positron source

International Nuclear Information System (INIS)

Pei Guoxi; Sun Yaolin; Liu Jintong; Chi Yunlong; Liu Yucheng; Liu Nianzong

2006-01-01

BEPC II-an upgrade project of the Beijing Electron Positron Collider (BEPC) is a factory type of e + e - collider. The fundamental requirements for its injector linac are the beam energy of 1.89 GeV for on-energy injection and a 40 mA positron beam current at the linac end with a low beam emittance of 1.6 μm and a low energy spread of ±0.5% so as to guarantee a higher injection rate (≥50 mA/min) to the storage ring. Since the positron flux is proportional to the primary electron beam power on the target, the authors will increase the electron gun current from 4A to 10A by using a new electron gun system and increase the primary electron energy from 120 MeV to 240 MeV. The positron source itself is an extremely important system for producing more positrons, including a positron converter target chamber, a 12kA flux modulator, the 7m focusing module with DC power supplies and the support. The new positron production linac from the electron gun to the positron source has been installed into the tunnel. In what follows, the authors will emphasize the positron source design, manufacture and tests. (authors)
Precision and broadband frequency swept laser source based on high-order modulation-sideband injection-locking.

Science.gov (United States)

Wei, Fang; Lu, Bin; Wang, Jian; Xu, Dan; Pan, Zhengqing; Chen, Dijun; Cai, Haiwen; Qu, Ronghui

2015-02-23

A precision and broadband laser frequency swept technique is experimentally demonstrated. Using synchronous current compensation, a slave diode laser is dynamically injection-locked to a specific high-order modulation-sideband of a narrow-linewidth master laser modulated by an electro-optic modulator (EOM), whose driven radio frequency (RF) signal can be agilely, precisely controlled by a frequency synthesizer, and the high-order modulation-sideband enables multiplied sweep range and tuning rate. By using 5th order sideband injection-locking, the original tuning range of 3 GHz and tuning rate of 0.5 THz/s is multiplied by 5 times to 15 GHz and 2.5 THz/s respectively. The slave laser has a 3 dB-linewidth of 2.5 kHz which is the same to the master laser. The settling time response of a 10 MHz frequency switching is 2.5 µs. By using higher-order modulation-sideband and optimized experiment parameters, an extended sweep range and rate could be expected.
Investigation of Solar and Solar-Gas Thermal Energy Sources

OpenAIRE

Ivan Herec; Jan Zupa

2003-01-01

The article deals with the investigation of solar thermal sources of electrical and heat energy as well as the investigation of hybrid solar-gas thermal sources of electrical and heat energy (so called photothermal sources). Photothermal sources presented here utilize computer-controlled injection of the conversion fluid into special capillary porous substance that is adjusted to direct temperature treatment by the concentrated thermal radiation absorption.
Subcutaneous Injections

DEFF Research Database (Denmark)

Thomsen, Maria

This thesis is about visualization and characterization of the tissue-device interaction during subcutaneous injection. The tissue pressure build-up during subcutaneous injections was measured in humans. The insulin pen FlexTouchr (Novo Nordisk A/S) was used for the measurements and the pressure ...
Hydromorphone Injection

Science.gov (United States)

... anyone else to use your medication. Store hydromorphone injection in a safe place so that no one else can use it accidentally or on purpose. Keep track of how much medication is left so ... with hydromorphone injection may increase the risk that you will develop ...
Ketorolac Injection

Science.gov (United States)

... an older adult, you should know that ketorolac injection is not as safe as other medications that can be used to treat your condition. Your doctor may choose to prescribe a different medication ... to ketorolac injection.Your doctor or pharmacist will give you the ...
Sonographically guided deep plantar fascia injections: where does the injectate go?

Science.gov (United States)

Maida, Eugene; Presley, James C; Murthy, Naveen; Pawlina, Wojciech; Smith, Jay

2013-08-01

To determine the distribution of sonographically guided deep plantar fascia injections in an unembalmed cadaveric model. A single experienced operator completed 10 sonographically guided deep plantar fascia injections in 10 unembalmed cadaveric specimens (5 right and 5 left) obtained from 6 donors (2 male and 4 female) aged 49 to 95 years (mean, 77.5 years) with a mean body mass index of 23.2 kg/m(2) (range, 18.4-26.3 kg/m(2)). A 12-3-MHz linear array transducer was used to direct a 22-gauge, 38-mm stainless steel needle deep to the plantar fascia at the anterior aspect of the calcaneus using an in-plane, medial-to-lateral approach. In each case, 1.5 mL of 50% diluted colored latex was injected deep to the plantar fascia. After a minimum of 72 hours, study coinvestigators dissected each specimen to assess injectate placement. All 10 injections accurately placed latex adjacent to the deep side of the plantar fascia at the anterior calcaneus. However, the flexor digitorum brevis (FDB) origin from the plantar fascia variably limited direct latex contact with the plantar fascia, and small amounts of latex interdigitated with the FDB origin in 90% (9 of 10). In all 10 specimens, latex also covered the traversing first branch of the lateral plantar nerve (FBLPN, ie, Baxter nerve) between the FDB and quadratus plantae muscles. No latex was found in the plantar fat pad or plantar fascia in any specimen. Sonographically guided deep plantar fascia injections reliably deliver latex deep to the plantar fascia while avoiding intrafascial injection. However, the extent of direct plantar fascia contact is variable due to the intervening FDB. On the contrary, the traversing FBLPN is reliably covered by the injection. Deep plantar fascia injections may have a role in the management of refractory plantar fasciitis, particularly following failed superficial perifascial or intrafascial injections, in cases of preferential deep plantar fascia involvement, or when entrapment
Pharmacy practice and injection use in community pharmacies in Pokhara city, Western Nepal.

Science.gov (United States)

Gyawali, Sudesh; Rathore, Devendra Singh; Adhikari, Kishor; Shankar, Pathiyil Ravi; K C, Vikash Kumar; Basnet, Suyog

2014-04-28

Community pharmacies in Nepal serve as the first point of contact for the public with the health care system and provide many services, including administering injections. However, there is a general lack of documented information on pharmacy practice and injection use in these pharmacies. This study aims to provide information about pharmacy practice in terms of service and drug information sources, and injection use, including the disposal of used injection equipment. A mixed method, cross-sectional study was conducted in 54 community pharmacies in Pokhara city. Data was collected using a pre-tested, semi-structured questionnaire, and also by the direct observation of pharmacy premises. Interviews with pharmacy supervisors (proprietors) were also conducted to obtain additional information about certain points. Interviews were carried out with 54 pharmacy supervisors/proprietors (47 males and 7 females) with a mean age and experience of 35.54 and 11.73 years, respectively. Approximately a half of the studied premises were operated by legally recognized pharmaceutical personnel, while the remainder was run by people who did not have the legal authority to operate pharmacies independently. About a quarter of pharmacies were providing services such as the administration of injections, wound dressing, and laboratory and consultation services in addition to medicine dispensing and counseling services. The 'Current Index of Medical Specialties' was the most commonly used source for drug information. Almost two-thirds of patients visiting the pharmacies were dispensed medicines without a prescription. Tetanus Toxoid, Depot-Medroxy Progesterone Acetate, and Diclofenac were the most commonly-used/administered injections. Most of the generated waste (including sharps) was disposed of in a municipal dump without adhering to the proper procedures for the disposal of hazardous waste. Community pharmacies in Pokhara offer a wide range of services including, but not limited to

Applications of Indus-1 synchrotron radiation source

International Nuclear Information System (INIS)

Nandedkar, R.V.

2003-01-01

Indus-1 is a 450 MeV electron storage ring. This is a soft X-ray and Vacuum Ultra Violet radiation source with the critical wavelength being 61 A. In this source, the first beam was stored in mid-1999 and was then made available, after initial storage and beam cleaning of the vacuum components, for beamline installation in the early 2000. Two beamlines are commissioned and are working. Other beamlines are in the advanced stage of commissioning. For Indus-1, the injection system consists of a 20 MeV classical microtron as a preinjector and a booster synchrotron that can go up to 700 MeV. For Indus-1, the injection into the storage ring is at full 450 MeV from this booster synchrotron
High thermal conductivity connector having high electrical isolation

Science.gov (United States)

Nieman, Ralph C.; Gonczy, John D.; Nicol, Thomas H.

1995-01-01

A method and article for providing a low-thermal-resistance, high-electrical-isolation heat intercept connection. The connection method involves clamping, by thermal interference fit, an electrically isolating cylinder between an outer metallic ring and an inner metallic disk. The connection provides durable coupling of a heat sink and a heat source.
Devonian sand injections and volcanism in the Murzuq Basin (south-west Libya)

DEFF Research Database (Denmark)

Moreau, Julien; Ghienne, Jean-Francois

system is original by its interaction with volcanism and its situation in an epicontinental intracratonic basin. The sand injections form a seal-bypass system between the Ordovician-Cambrian reservoirs and the Lower Devonian sandstones, breaching through the Silurian shale seal (and source rock...
Molecular epidemiology of nontuberculous mycobacteria isolates from clinical and environmental sources of a metropolitan city.

Science.gov (United States)

Velayati, Ali Akbar; Farnia, Parissa; Mozafari, Mohadese; Malekshahian, Donya; Seif, Shima; Rahideh, Snaz; Mirsaeidi, Mehdi

2014-01-01

While NTM infection is mainly acquired from environmental exposure, monitoring of environmental niches for NTM is not a routine practice. This study aimed to find the prevalence of environmental NTM in soil and water in four highly populated suburbs of Tehran, Iran. A total of 4014 samples from soil and water resources were collected and studied. Sediments of each treated sample were cultured in Lowenstein-Jensen medium and observed twice per week for growth rate, colony morphology, and pigmentation. Colonies were studied with phenotypic tests. Molecular analysis was performed on single colonies derived from subculture of original isolates. Environmental samples were compared with 34 NTM isolates from patients who were residents of the study locations. Out of 4014 samples, mycobacteria were isolated from 862 (21.4%) specimens; 536 (62.1%) belonged to slow growing mycobacteria (SGM) and 326 (37.8%) were rapid growing mycobacteria (RGM). The five most frequent NTM were M. farcinogens (105/862; 12.1%), M. fortuitum (72/862; 8.3%), M. senegalense (58/862; 6.7%), M. kansasii (54/862; 6.2%), and M. simiae (46/862; 5.3%). In total, 62.5% (539/862) of mycobacterial positive samples were isolated from water and only 37.4% (323/862) of them were isolated from soil samples (Pdistribution pattern of environmental NTM isolates with clinical isolates suggests a possible transmission link, but this does not apply to all environmental NTM species. Our study confirms an increasing trend of NTM isolation from clinical samples that needs further investigation.
Paclitaxel Injection

Science.gov (United States)

(pak'' li tax' el)Paclitaxel injection must be given in a hospital or medical facility under the supervision of a doctor who is experienced in giving chemotherapy medications for cancer.Paclitaxel injection may cause a large decrease in the number of white blood cells (a type of blood cell ...
Injecting behaviour and service use among young injectors in Albania, Moldova, Romania and Serbia.

Science.gov (United States)

Busza, Joanna; Douthwaite, Megan; Bani, Roland; Scutelniciuc, Otilia; Preda, Marian; Simic, Danijela

2013-09-01

This study examines socio-demographic profiles, injecting risk and use of health services among young injectors (15-24) in Albania, Moldova, Romania and Serbia. The objective was to provide age-disaggregated data to identify differences between adolescents (Romania, surveys were conducted in the capitals, respectively, Bucharest and Tirana. Respondents were recruited from 3 cities in Moldova (Chisinau, Balti and Tiraspol) and Serbia (Belgrade, Novi Sad and Nis). Data were collected on risk behaviours, service use and contact with police and other authorities. Analysis focused on associations between unsafe injecting behaviour and key determinants including demographic background, source of needles/syringes, use of harm reduction services and interactions with law enforcement. Although drug use and health-seeking varied across settings, sources of injecting equipment were significantly associated with sharing needles and syringes in Moldova, Romania and Serbia. Obtaining equipment from formal sources (pharmacies, needle-exchange programmes) reduced likelihood of sharing significantly, while being stopped by the police or incarcerated increased it. Adolescents relied on pharmacies more than public sector services to obtain equipment. Adolescents comprise a small proportion of PWID in this region, but have poorer access to harm reduction services than older peers. Engaging young PWID through private and public sector outlets might reduce unsafe practices, while use of the justice system to address drug use complicates efforts to reach this population. Copyright © 2013 Elsevier B.V. All rights reserved.
Halotolerant streptomycetes isolated from soil at Taif region ...

African Journals Online (AJOL)

This study focuses on isolation and purification of some halotolerant streptomycetes from soil and sea water of western region, KSA as a source of salt tolerance gene(s). A few numbers (32) of streptomycetes-like colonies (SLC) were isolated and purified from two regions. From Jeddah, a number of 22 out of the 32 SLC ...
Molecular characterization of Azotobacter spp. nifH gene Isolated ...

African Journals Online (AJOL)

The Azotobacter species was isolated from marine source in two different seasons. They were cultivated under laboratory conditions using Nitrogen free Azotobacter specific medium. We observed that they were present in both seasons. The phylogenetic tree revealed that our isolated Azotobacter spp. was distantly related ...
Hydrocarbon-degradation by Isolate Pseudomonas lundensis UTAR FPE2

Directory of Open Access Journals (Sweden)

Adeline, S. Y. Ting

2009-01-01

Full Text Available In this study, the potential of isolate Pseudomonas lundensis UTAR FPE2 as a hydrocarbon degrader was established. Their biodegradation activity was first detected with the formation of clearing zones on Bushnell-Hass agar plates, with the largest diameter observed on plates supplemented with paraffin, followed by mineral oil and petrol. Utilization of hydrocarbon sources were again detected in broth cultures supplemented with similar hydrocarbon substrates, where the mean viable cell count recovered from hydrocarbon-supplemented broth cultures were higher than the initial inoculum except for napthalene. In both tests, the isolate showed higher degradability towards aliphatic hydrocarbon sources, and the least activity towards the aromatic hydrocarbon naphthalene. The isolate P. lundensis UTAR FPE2 (8 log10 cfu/mL also degraded crude diesel sample, with 69% degradation during the first three days. To conclude, this study suggests the potential use of this isolate for bioremediation of hydrocarbon-contaminated environments.
Doppler-shift spectra of Hα lines from negative-ion-based neutral beams for large helical device neutral beam injection

International Nuclear Information System (INIS)

Oka, Y.; Ikeda, K.; Takeiri, Y.; Tsumori, K.; Kaneko, O.; Nagaoka, K.; Osakabe, M.; Asano, E.; Kondo, T.; Sato, M.; Shibuya, M.; Grisham, L.; Umeda, N.; Honda, A.; Ikeda, Y.; Yamamoto, T.

2006-01-01

The velocity spectra of the negative-ion-(H - ) based neutral beams are studied in high-performance large-area ion sources during injection into large helical device fusion plasmas. We are conducting systematic observations in standard neutral beam injection to correlate beam spectra with source operating conditions. Almost all of the transmitted beam power was at full acceleration energy (∼170 keV). The small stripping beam component which was produced in the extraction gap was evaluated to be about 9%-22% by amplitude of the measured spectra for the sources in beam lines 1 and 2. H - production uniformity from the spectrum profile was 86%-90% for three sources. For the longest pulse injection during 74 and 128 s, a full energy component tended to decrease with time, while the accelerator gap stripping tail tended to increase slightly with time, which is attributed to beam-induced outgassing in the accelerator. A higher conductance multislot ground grid accelerator appeared to show little growth in the accelerator gap beam stripping during long pulses compared to the conventional multiaperture ground grid. The beam uniformity appeared to vary in part with the Cs uniformity on the plasma grid
Ion source requirements for pulsed spallation neutron sources

International Nuclear Information System (INIS)

Alonso, J.R.

1996-01-01

The neutron scattering community has endorsed the need for a high-power (1 to 5 MW) accelerator-driven source of neutrons for materials research. Properly configured, the accelerator could produce very short (sub-microsecond) bursts of cold neutrons, said time structure offering advantages over the continuous flux from a reactor for a large class of experiments. The recent cancellation of the ANS reactor project has increased the urgency to develop a comprehensive strategy based on the best technological scenarios. Studies to date have built on the experience from ISIS (the 160 kW source in the UK), and call for a high-current (approx. 100 mA peak) H - source-linac combination injecting into one or more accumulator rings in which beam may be further accelerated. The 1 to 5 GeV proton beam is extracted in a single turn and brought to the target-moderator stations. The high current, high duty-factor, high brightness and high reliability required of the ion source present a very large challenge to the ion source community. A workshop held in Berkeley in October 1994, analyzed in detail the source requirements for proposed accelerator scenarios, the present performance capabilities of different H - source technologies, and identified necessary R ampersand D efforts to bridge the gap. copyright 1996 American Institute of Physics
Considerations and calculations for the neutral-injection system in ZEPHYR

International Nuclear Information System (INIS)

Feist, J.H.; Herrmann, W.; Speth, E.

1981-01-01

The heating of the ZEPHYR plasma to ignition temperatures shall be accomplished by neutral injection and subsequent compression of the plasma. 25 MW of neutral power are required. A parametrical study of beam transmission was performed to find limitations on the type and arrangement of sources imposed by the small width of the porthole to the torus and the small height of the plasma target. A reference beam line has been designed and the power transmission calculated as a function of gas flow through the sources. The limitations mentioned make it necessary to design the beam lines as compact as possible to avoid intolerable losses in the duct or power outside the plasma target. Depending on the reliability of a single source, the number of sources that are available in at least 75 % of the discharges has been calculated for different numbers of installed sources. (author)
RF H-minus ion source development in China spallation neutron source

Science.gov (United States)

Chen, W.; Ouyang, H.; Xiao, Y.; Liu, S.; Lü, Y.; Cao, X.; Huang, T.; Xue, K.

2017-08-01

China Spallation Neutron Source (CSNS) phase-I project currently uses a Penning surface plasma H- ion source, which has a life time of several weeks with occasional sparks between high voltage electrodes. To extend the life time of the ion source and prepare for the CSNS phase-II, we are trying to develop a RF negative hydrogen ion source with external antenna. The configuration of the source is similar to the DESY external antenna ion source and SNS ion source. However several changes are made to improve the stability and the life time. Firstly, Si3N4 ceramic with high thermal shock resistance, and high thermal conductivity is used for plasma chamber, which can endure an average power of 2000W. Secondly, the water-cooled antenna is brazed on the chamber to improve the energy efficiency. Thirdly, cesium is injected directly to the plasma chamber if necessary, to simplify the design of the converter and the extraction. Area of stainless steel exposed to plasma is minimized to reduce the sputtering and degassing. Instead Mo, Ta, and Pt coated materials are used to face the plasma, which makes the self-cleaning of the source possible.
Prototype ion source for JT-60 neutral beam injectors

International Nuclear Information System (INIS)

Akiba, M.

1981-01-01

A prototype ion source for JT-60 neutral beam injectors has been fabricated and tested. Here, we review the construction of the prototype ion source and report the experimental results about the source characteristics that has been obtained at this time. The prototype ion source is now installed at the prototype unit of JT-60 neutral beam injection units and the demonstration of the performances of the ion source and the prototype unit has just started
An investigation of methods for injecting emissions from boreal wildfires using WRF-Chem during ARCTAS

Science.gov (United States)

Sessions, W. R.; Fuelberg, H. E.; Kahn, R. A.; Winker, D. M.

2011-06-01

The Weather Research and Forecasting Model (WRF) is considered a "next generation" mesoscale meteorology model. The inclusion of a chemistry module (WRF-Chem) allows transport simulations of chemical and aerosol species such as those observed during NASA's Arctic Research of the Composition of the Troposphere from Aircraft and Satellites (ARCTAS) in 2008. The ARCTAS summer deployment phase during June and July coincided with large boreal wildfires in Saskatchewan and Eastern Russia. One of the most important aspects of simulating wildfire plume transport is the height at which emissions are injected. WRF-Chem contains an integrated one-dimensional plume rise model to determine the appropriate injection layer. The plume rise model accounts for thermal buoyancy associated with fires and local atmospheric stability. This paper describes a case study of a 10 day period during the Spring phase of ARCTAS. It compares results from the plume model against those of two more traditional injection methods: Injecting within the planetary boundary layer, and in a layer 3-5 km above ground level. Fire locations are satellite derived from the GOES Wildfire Automated Biomass Burning Algorithm (WF_ABBA) and the MODIS thermal hotspot detection. Two methods for preprocessing these fire data are compared: The prep_chem_sources method included with WRF-Chem, and the Naval Research Laboratory's Fire Locating and Monitoring of Burning Emissions (FLAMBE). Results from the simulations are compared with satellite-derived products from the AIRS, MISR and CALIOP sensors. When FLAMBE provides input to the 1-D plume rise model, the resulting injection heights exhibit the best agreement with satellite-observed injection heights. The FLAMBE-derived heights are more realistic than those utilizing prep_chem_sources. Conversely, when the planetary boundary layer or the 3-5 km a.g.l. layer were filled with emissions, the resulting injection heights exhibit less agreement with observed plume heights
Isolated transient aphasia at emergency presentation is associated with a high rate of cardioembolic embolism.

Science.gov (United States)

Wasserman, Jason K; Perry, Jeffrey J; Dowlatshahi, Dar; Stotts, Grant; Sivilotti, Marco L A; Worster, Andrew; Emond, Marcel; Sutherland, Jane; Stiell, Ian G; Sharma, Mukul

2015-11-01

A cardiac source is often implicated in strokes where the deficit includes aphasia. However, less is known about the etiology of isolated aphasia during transient ischemic attack (TIA). Our objective was to determine whether patients with isolated aphasia are likely to have a cardioembolic etiology for their TIA. We prospectively studied a cohort of TIA patients in eight tertiary-care emergency departments. Patients with isolated aphasia were identified by the treating physician at the time of emergency department presentation. Patients with dysarthria (i.e., a phonation disturbance) were not included. Potential cardiac sources for embolism were defined as atrial fibrillation on history, electrocardiogram, Holter monitor, atrial fibrillation on echocardiography, or thrombus on echocardiography. Of the 2,360 TIA patients identified, 1,155 had neurological deficits at the time of the emergency physician assessment and were included in this analysis, and 41 had isolated aphasia as their only neurological deficit. Patients with isolated aphasia were older (73.9±10.0 v. 67.2±14.5 years; p=0.003), more likely to have a history of heart failure (9.8% v. 2.6%; p=0.027), and were twice as likely to have any cardiac source of embolism (22.0% v. 10.6%; p=0.037). Isolated aphasia is associated with a high rate of cardioembolic sources of embolism after TIA. Emergency patients with isolated aphasia diagnosed with a TIA warrant a rapid and thorough assessment for a cardioembolic source.
Localization of gravitational wave sources with networks of advanced detectors

International Nuclear Information System (INIS)

Klimenko, S.; Mitselmakher, G.; Pankow, C.; Vedovato, G.; Drago, M.; Prodi, G.; Mazzolo, G.; Salemi, F.; Re, V.; Yakushin, I.

2011-01-01

Coincident observations with gravitational wave (GW) detectors and other astronomical instruments are among the main objectives of the experiments with the network of LIGO, Virgo, and GEO detectors. They will become a necessary part of the future GW astronomy as the next generation of advanced detectors comes online. The success of such joint observations directly depends on the source localization capabilities of the GW detectors. In this paper we present studies of the sky localization of transient GW sources with the future advanced detector networks and describe their fundamental properties. By reconstructing sky coordinates of ad hoc signals injected into simulated detector noise, we study the accuracy of the source localization and its dependence on the strength of injected signals, waveforms, and network configurations.
Compressed air injection technique to standardize block injection pressures : [La technique d'injection d'air comprimé pour normaliser les pressions d'injection d'un blocage nerveux].

Science.gov (United States)

Tsui, Ban C H; Li, Lisa X Y; Pillay, Jennifer J

2006-11-01

Presently, no standardized technique exists to monitor injection pressures during peripheral nerve blocks. Our objective was to determine if a compressed air injection technique, using an in vitro model based on Boyle's law and typical regional anesthesia equipment, could consistently maintain injection pressures below a 1293 mmHg level associated with clinically significant nerve injury. Injection pressures for 20 and 30 mL syringes with various needle sizes ( 18G, 20G, 21 G, 22G, and 24G) were measured in a closed system. A set volume of air was aspirated into a saline-filled syringe and then compressed and maintained at various percentages while pressure was measured. The needle was inserted into the injection port of a pressure sensor, which had attached extension tubing with an injection plug clamped "off". Using linear regression with all data points, the pressure value and 99% confidence interval (CI) at 50% air compression was estimated. The linearity of Boyle's law was demonstrated with a high correlation, r = 0.99, and a slope of 0.984 (99% CI: 0.967-1.001). The net pressure generated at 50% compression was estimated as 744.8 mmHg, with the 99% CI between 729.6 and 760.0 mmHg. The various syringe/needle combinations had similar results. By creating and maintaining syringe air compression at 50% or less, injection pressures will be substantially below the 1293 mmHg threshold considered to be an associated risk factor for clinically significant nerve injury. This technique may allow simple, real-time and objective monitoring during local anesthetic injections while inherently reducing injection speed. Présentement, aucune technique normalisée ne permet de vérifier les pressions d'injection pendant les blocages nerveux périphériques. Nous voulions vérifier si une technique d'injection d'air comprimé, utilisant un modèle in vitro fondé sur la loi de Boyle et du matériel propre à l'anesthésie régionale, pouvait maintenir avec régularité les
Comparative study of diode-pumping self-injection and injection-locking Tm:YAG lasers

International Nuclear Information System (INIS)

Wu, C T; Chen, F; Ju, Y L; Wang, Y Z

2013-01-01

A comparative study of the laser characteristics of self-injection and injection-locking Tm:YAG lasers is given in this paper. At a pump energy of 145 mJ and Q-switched repetition rate of 100 Hz, an output energy of 2.39 mJ was obtained for an injection-locking Tm:YAG laser, with a pulse width of 403.2 ns and a pulse building-up time of 2.12 μs. Under the same conditions, the output energy, pulse width and pulse build-up time for a self-injection Tm:YAG laser were 2.21 mJ, 407.0 ns and 3.95 μs, respectively. The threshold of the Q-switched injection-locking Tm:YAG laser was much lower than that of the self-injection laser, and the pulse width was narrower and the pulse build-up time shorter. Additionally, the output spectrum was much purer for the injection-locking laser. (paper)
Bacterial isolates from the bryozoan Membranipora membranacea: influence of culture media on isolation and antimicrobial activity.

Science.gov (United States)

Heindl, Herwig; Thiel, Vera; Wiese, Jutta; Imhoff, Johannes F

2012-03-01

From specimens of the bryozoan Membranipora membranacea collected in the Baltic Sea, bacteria were isolated on four different media, which significantly increased the diversity of the isolated groups. All isolates were classified according to 16S rRNA gene sequence analysis and tested for antimicrobial properties using a panel of five indicator strains and six different media. Each medium featured a unique set of isolated phylotypes, and a phylogenetically diverse collection of isolates was obtained. A total of 96 isolates were assigned to 49 phylotypes and 29 genera. Only one-third of the members of these genera had been isolated previously from comparable sources. The isolates were affiliated with Alpha- and Gammaproteobacteria, Bacilli, and Actinobacteria. A comparable large portion of up to 22 isolates, i.e., 15 phylotypes, probably represent new species. Likewise, 47 isolates (approximately 50%) displayed antibiotic activities, mostly against grampositive indicator strains. Of the active strains, 63.8 % had antibiotic traits only on one or two of the growth media, whereas only 12.7 % inhibited growth on five or all six media. The application of six different media for antimicrobial testing resulted in twice the number of positive hits as obtained with only a single medium. The use of different media for the isolation of bacteria as well as the variation of media considered suitable for the production of antibiotic substances significantly enhanced both the number of isolates obtained and the proportion of antibiotic active cultures. Thus the approach described herein offers an improved strategy in the search for new antibiotic compounds.

Calculation method of water injection forward modeling and inversion process in oilfield water injection network

Science.gov (United States)

Liu, Long; Liu, Wei

2018-04-01

A forward modeling and inversion algorithm is adopted in order to determine the water injection plan in the oilfield water injection network. The main idea of the algorithm is shown as follows: firstly, the oilfield water injection network is inversely calculated. The pumping station demand flow is calculated. Then, forward modeling calculation is carried out for judging whether all water injection wells meet the requirements of injection allocation or not. If all water injection wells meet the requirements of injection allocation, calculation is stopped, otherwise the demand injection allocation flow rate of certain step size is reduced aiming at water injection wells which do not meet requirements, and next iterative operation is started. It is not necessary to list the algorithm into water injection network system algorithm, which can be realized easily. Iterative method is used, which is suitable for computer programming. Experimental result shows that the algorithm is fast and accurate.
Isolation of Moellerella wisconsensis from the lung of a goat.

Science.gov (United States)

Casalinuovo, F; Musarella, R

2009-09-18

This report describes the first isolation of Moellerella wisconsensis from the lung of a goat in Italy and represents the fourth isolation of this rare enterobacterial species from non-human sources reported in the literature. In fact, since its first isolation, M. wisconsensis has only been described in a few other occasions and often in clinical samples associated with cases of human enteritis.
Selection and design of ion sources for use at the Holifield radioactive ion beam facility

International Nuclear Information System (INIS)

Alton, G.D.; Haynes, D.L.; Mills, G.D.; Olsen, D.K.

1994-01-01

The Holifield Radioactive Ion Beam Facility now under construction at the Oak Ridge National Laboratory will use the 25 MV tandem accelerator for the acceleration of radioactive ion beams to energies appropriate for research in nuclear physics; negative ion beams are, therefore, required for injection into the tandem accelerator. Because charge exchange is an efficient means for converting initially positive ion beams to negative ion beams, both positive and negative ion sources are viable options for use at the facility. The choice of the type of ion source will depend on the overall efficiency for generating the radioactive species of interest. Although direct-extraction negative ion sources are clearly desirable, the ion formation efficiencies are often too low for practical consideration; for this situation, positive ion sources, in combination with charge exchange, are the logical choice. The high-temperature version of the CERN-ISOLDE positive ion source has been selected and a modified version of the source designed and fabricated for initial use at the facility because of its low emittance, relatively high ionization efficiencies, and species versatility, and because it has been engineered for remote installation, removal, and servicing as required for safe handling in a high-radiation-level ISOL facility. The source will be primarily used to generate ion beams from elements with intermediate to low electron affinities. Prototype plasma-sputter negative ion sources and negative surface-ionization sources are under design consideration for generating radioactive ion beams from high-electron-affinity elements. The design features of these sources and expected efficiencies and beam qualities (emittances) will be described in this report
Worldwide Injection Technique Questionnaire Study: Injecting Complications and the Role of the Professional.

Science.gov (United States)

Frid, Anders H; Hirsch, Laurence J; Menchior, Astrid R; Morel, Didier R; Strauss, Kenneth W

2016-09-01

From February 1, 2014, through June 30, 2015, 13,289 insulin-injecting patients from 423 centers in 42 countries participated in one of the largest surveys ever performed in diabetes. The first results of this survey are published elsewhere in this issue. Herein we report that the most common complication of injecting insulin is lipohypertrophy (LH), which was self-reported by 29.0% of patients and found by physical examination in 30.8% by health care professionals (HCPs). Patients with LH consumed a mean of 10.1 IU more insulin daily than patients without LH. Glycated hemoglobin levels averaged 0.55% higher in patients with vs without LH. Lipohypertrophy was associated with higher rates of unexplained hypoglycemia and glycemic variability as well as more frequent diabetic ketoacidosis, incorrect rotation of injection sites, use of smaller injection zones, longer duration of insulin use, and reuse of pen needles (each P<.05). Routine inspection of injection sites by the HCP was associated with lower glycated hemoglobin levels, less LH, and more correct injection site rotation. Patients were also more likely to rotate correctly if they received injection instructions from their HCP in the past 6 months. Fewer than 40% of patients claimed to have gotten such instructions in the past 6 months, and 10% said that they have never received training on how to inject correctly despite injecting for a mean of nearly 9 years. Use of these data should stimulate renewed commitment to optimizing insulin injection practices. Copyright © 2016 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.
Hydrogen/oxygen injection stopping method for nuclear power plant and emergent hydrogen/oxygen injection device

International Nuclear Information System (INIS)

Ishida, Ryoichi; Ota, Masamoto; Takagi, Jun-ichi; Hirose, Yuki

1998-01-01

The present invention provides a device for suppressing increase of electroconductivity of reactor water during operation of a BWR type reactor, upon occurrence of reactor scram of the plant or upon stopping of hydrogen/oxygen injection due to emergent stoppage of an injection device so as not to deteriorate the integrity of a gas waste processing system upon occurrence of scram. Namely, when injection of hydrogen/oxygen is stopped during plant operation, the injection amount of hydrogen is reduced gradually. Subsequently, injection of hydrogen is stopped. With such procedures, the increase of electroconductivity of reactor water can be suppressed upon stoppage of hydrogen injection. When injection of hydrogen/oxygen is stopped upon shut down of the plant, the amount of hydrogen injection is changed depending on the change of the feedwater flow rate, and then the plant is shut down while keeping hydrogen concentration of feedwater to a predetermined value. With such procedures, increase of the reactor water electroconductivity can be suppressed upon stoppage of hydrogen injection. Upon emergent stoppage of the hydrogen/oxygen injection device, an emergent hydrogen/oxygen injection device is actuated to continue the injection of hydrogen/oxygen. With such procedures, elevation of reactor water electroconductivity can be suppressed. (I.S.)
Optical power equalization for upstream traffic with injection-locked Fabry-Perot lasers in TDM-PON

Science.gov (United States)

Huang, Ting-Tsan; Sheu, Lih-Gen; Chi, Sien

2010-10-01

An optical power equalization of upstream traffic in time-division-multiplexed passive optical network (TDM-PON) based on injection-locked Fabry-Perot lasers has been experimentally investigated. The upstream transmitters with stable spectrum are achieved by using an external injection light source in the optical line terminal (OLT). The different upstream powers can be equalized by injection locking a Fabry-Perot laser diode (FP-LD) biased below threshold current in OLT. The dynamic upstream power range from - 8.5 to - 19.5 db m is reduced to a 1.6 dB maximal power variation, when the uplink signal is directly modulated at 1.25 Gb/s.
Scenedesmus sp. NJ-1 isolated from Antarctica: a suitable renewable lipid source for biodiesel production.

Science.gov (United States)

Chen, Zhuo; Gong, Yangmin; Fang, Xiantao; Hu, Hanhua

2012-11-01

Microalgal lipids are promising alternative feedstocks for biodiesel production. Scenedesmus sp. NJ-1, an oil-rich freshwater microalga isolated from Antarctica, was identified to be a suitable candidate to produce biodiesel in this study. This strain could grow at temperatures ranging from 4 to 35 °C. With regular decrease in nitrate concentration in the medium, large quantities of triacylglycerols accumulated under batch culture conditions detected by thin layer chromatography and BODIPY 505/515 fluorescent staining. Scenedesmus sp. NJ-1 achieved the average biomass productivity of 0.105 g l⁻¹ d⁻¹ (dry weight) and nearly the highest lipid content (35 % of dry cell weight) was reached at day 28 in the batch culture. Neutral lipids accounted for 78 % of total lipids, and C18:1 (n-9), C16:0 were the major fatty acids in total lipids, composing 37 and 20 % of total fatty acids of Scenedesmus sp. NJ-1 grown for 36 days, respectively. These results suggested that Scenedesmus sp. NJ-1 was a good source of microalgal oils for biodiesel production.
Conflict of interest in the assessment of hyaluronic acid injections for osteoarthritis of the knee: an updated systematic review.

Science.gov (United States)

Printz, Jonathon O; Lee, John J; Knesek, Michael; Urquhart, Andrew G

2013-09-01

The search results of a recent systematic review of prospective, randomized, placebo-controlled trials on hyaluronic acid injections for knee arthritis were updated and reviewed for funding source and qualitative conclusions. Forty-eight studies were identified; 30 (62.5%) were industry funded, and 3 (6.25%) were not. Fifteen (31.3%) studies did not identify a funding source. An association was observed between a reported potential financial conflict of interest of the author and the qualitative conclusion (P=0.018). None of the studies with a reported financial conflict of interest of at least one author had an unfavorable conclusion; 11 (35%) of the 31 studies with no industry-affiliated authors indicated that hyaluronic acid injection for knee osteoarthritis was no more effective than a placebo injection. © 2013 Elsevier Inc. All rights reserved.
Penicillin G Procaine Injection

Science.gov (United States)

Penicillin G procaine injection is used to treat certain infections caused by bacteria. Penicillin G procaine injection should not be used to ... early in the treatment of certain serious infections. Penicillin G procaine injection is in a class of ...
Reliability and cost evaluation of small isolated power systems containing photovoltaic and wind energy

Science.gov (United States)

Karki, Rajesh

Renewable energy application in electric power systems is growing rapidly worldwide due to enhanced public concerns for adverse environmental impacts and escalation in energy costs associated with the use of conventional energy sources. Photovoltaics and wind energy sources are being increasingly recognized as cost effective generation sources. A comprehensive evaluation of reliability and cost is required to analyze the actual benefits of utilizing these energy sources. The reliability aspects of utilizing renewable energy sources have largely been ignored in the past due the relatively insignificant contribution of these sources in major power systems, and consequently due to the lack of appropriate techniques. Renewable energy sources have the potential to play a significant role in the electrical energy requirements of small isolated power systems which are primarily supplied by costly diesel fuel. A relatively high renewable energy penetration can significantly reduce the system fuel costs but can also have considerable impact on the system reliability. Small isolated systems routinely plan their generating facilities using deterministic adequacy methods that cannot incorporate the highly erratic behavior of renewable energy sources. The utilization of a single probabilistic risk index has not been generally accepted in small isolated system evaluation despite its utilization in most large power utilities. Deterministic and probabilistic techniques are combined in this thesis using a system well-being approach to provide useful adequacy indices for small isolated systems that include renewable energy. This thesis presents an evaluation model for small isolated systems containing renewable energy sources by integrating simulation models that generate appropriate atmospheric data, evaluate chronological renewable power outputs and combine total available energy and load to provide useful system indices. A software tool SIPSREL+ has been developed which generates
Study of risk reduction by improving operation of reactor core isolation cooling system

International Nuclear Information System (INIS)

Watanabe, Yamato; Tazai, Ayuko; Yamagishi, Shohei; Muramatsu, Ken; Muta, Hitoshi

2014-01-01

The Fukushima Daiichi nuclear power plant fell into a station blackout (SBO) due to the earthquake and tsunami in which most of the core cooling systems were disabled. In the units 2 and 3, water injection to the core was performed only by water injection system with turbine driven pumps. In particular, it is inferred from observed plant parameters that the reactor core isolation cooling system (RCIC) continued its operation much longer than it was originally expected (8 hours). Since the preparation of safety measures did not work, the reactor core damaged. With a view to reduce risk of station blackout events in a BWR by accident management, this study investigated the efficacy of operation procedures that takes advantage of RCIC which can be operated with only equipment inside reactor building and does not require an AC power source. The efficacy was assessed in this study by two steps. The first step is a thermal hydraulic analysis with the RETRAN3D code to estimate the potential extension of duration of core cooling by RCIC and the second step is the estimation of time required for recovery of off-site power from experiences at nuclear power stations under the 3.11 earthquake. This study showed that it is possible to implement more reliable measures for accident termination and to greatly reduce the risk of SBO by the installation of accident management measures with use of RCIC for extension of core cooling under SBO conditions. (author)
Analysis of neutronics and dynamic characteristics with reactivity injection in LBE cooled sub-critical reactor

International Nuclear Information System (INIS)

Chen Sen; Wu Yican; Jin Ming; Chen Zhibin; Bai Yunqing; Zhao Zhumin

2014-01-01

Accelerator Driven Sub-critical System (ADS) has particular neutronics behaviors compared with the critical system. Prompt jump approximation point reactor kinetics equations taken external source into account have been deduced using an approach of prompt jump approximation. And the relationship between injection reactivity and power ampliation has been achieved. In addition, based on the RELAP5 code the prolong development of point reactor kinetics code used into assessing sub-critical system have been promoted. Different sub-criticality (k eff = 0.90, 0.95, 0.97, 0.98 and 0.99) have been assessed in preliminary design of a type of natural circulation cooling sub-critical reactor under conditions of reactivity injection +1 β in one second. It shows that the external source prompt transient approximation method has an accurate solution after injecting reactivity around short time and has a capacity to solve the dynamic equation, and the sub-critical system has an inner stability while the deeper sub-criticality the less impact on the sub-critical system. (authors)
The supply solutions for isolated rural consumers

International Nuclear Information System (INIS)

Hazi, Gheorghe; Solomon, Petre; Hazi, Aneta

2004-01-01

This paper establishes the supply optimal solutions for isolated rural consumers. A complex technical-economical calculation method is developed for selection of the best solutions. This analysis is based on the minimization of the net present value, NPV, criterion. Using the results of this calculation, one can select easily the supply solution for a given active power and for a given distance separating the power source and the isolated consumer. (authors)
Genotoxicological Evaluation of NUTRALYS Pea Protein Isolate

OpenAIRE

Aouatif, Chentouf; Looten, Ph.; Parvathi, M. V. S.; Raja Ganesh, S.; Paranthaman, V.

2013-01-01

NUTRALYS Pea Protein Isolate, a protein supplement, is a high-quality source of protein which is primarily emulsifying functional protein. We evaluated the genotoxic potential of NUTRALYS isolated from dry yellow pea, using three established genotoxicity tests (AMES test in vitro chromosomal aberration test, and in vivo micronucleus test) employing OECD guidelines under GLP conditions. In the bacterial reverse mutation test, NUTRALYS did not show positive responses in strains detecting point ...
Thoraco-abdominal high-pitch dual-source CT angiography: Experimental evaluation of injection protocols with an anatomical human vascular phantom

Energy Technology Data Exchange (ETDEWEB)

Puippe, Gilbert D., E-mail: gilbert.puippe@usz.ch [Institute for Diagnostic and Interventional Radiology, University Hospital Zurich, Switzerland Raemistrasse 100, CH-8091 Zurich (Switzerland); Winklehner, Anna [Institute for Diagnostic and Interventional Radiology, University Hospital Zurich, Switzerland Raemistrasse 100, CH-8091 Zurich (Switzerland); Hasenclever, Peter; Plass, André [Division of Cardiac and Vascular Surgery, University Hospital Zurich, Switzerland Raemistrasse 100, CH-8091 Zurich (Switzerland); Frauenfelder, Thomas; Baumueller, Stephan [Institute for Diagnostic and Interventional Radiology, University Hospital Zurich, Switzerland Raemistrasse 100, CH-8091 Zurich (Switzerland)

2012-10-15

Objective: To experimentally evaluate three different contrast injection protocols at thoraco-abdominal high-pitch dual-source computed tomography angiography (CTA), with regard to level and homogeneity of vascular enhancement at different cardiac outputs. Materials and methods: A uniphasic, a biphasic as well as an individually tailored contrast protocol were tested using a human vascular phantom. Each protocol was scanned at 5 different cardiac outputs (3–5 L/min, steps of 0.5 L/min) using an extracorporeal cardiac pump. Vascular enhancement of the thoraco-abdominal aorta was measured every 5 cm. Overall mean enhancement of each protocol and mean enhancement for each cardiac output within each protocol were calculated. Enhancement homogeneity along the z-axis was evaluated for each cardiac output and protocol. Results: Overall mean enhancement was significantly higher in the uniphasic than in the other two protocols (all p < .05), whereas the difference between the biphasic and tailored protocol was not significant (p = .76). Mean enhancement among each of the 5 cardiac outputs within each protocol was significantly different (all p < .05). Only within the tailored protocol mean enhancement differed not significantly at cardiac outputs of 3.5 L/min vs. 5 L/min (484 ± 25 HU vs. 476 ± 19 HU, p = .14) and 4 vs. 5 L/min (443 ± 49 HU vs. 476 ± 19 HU, p = .05). Both, uniphasic and tailored protocol yielded homogenous enhancement at all cardiac outputs, whereas the biphasic protocol failed to achieve homogenous enhancement. Conclusion: This phantom study suggests that diagnostic and homogenous enhancement at thoraco-abdominal high-pitch dual-source CTA is feasible with either a uniphasic or an individually tailored contrast protocol.
Novel methods for improvement of a Penning ion source for neutron generator applications.

Science.gov (United States)

Sy, A; Ji, Q; Persaud, A; Waldmann, O; Schenkel, T

2012-02-01

Penning ion source performance for neutron generator applications is characterized by the atomic ion fraction and beam current density, providing two paths by which source performance can be improved for increased neutron yields. We have fabricated a Penning ion source to investigate novel methods for improving source performance, including optimization of wall materials and electrode geometry, advanced magnetic confinement, and integration of field emitter arrays for electron injection. Effects of several electrode geometries on discharge characteristics and extracted ion current were studied. Additional magnetic confinement resulted in a factor of two increase in beam current density. First results indicate unchanged proton fraction and increased beam current density due to electron injection from carbon nanofiber arrays.
Hollow cathode for positive ion sources

International Nuclear Information System (INIS)

Schechter, D.E.; Kim, J.; Tsai, C.C.

1979-01-01

Development to incorporate hollow cathodes into high power ion sources for neutral beam injection systems is being pursued. Hollow tube LaB 6 -type cathodes, similar to a UCLA design, have been constructed and tested in several ORNL ion source configurations. Results of testing include arc discharge parameters of >1000 and 500 amps for 0.5 and 10 second pulse lengths, respectively. Details of cathode construction and additional performance results are discussed
Antiviral Potential of Algae Polysaccharides Isolated from Marine Sources: A Review

Directory of Open Access Journals (Sweden)

Azin Ahmadi

2015-01-01

Full Text Available From food to fertilizer, algal derived products are largely employed in assorted industries, including agricultural, biomedical, food, and pharmaceutical industries. Among different chemical compositions isolated from algae, polysaccharides are the most well-established compounds, which were subjected to a variety of studies due to extensive bioactivities. Over the past few decades, the promising results for antiviral potential of algae-derived polysaccharides have advocated them as inordinate candidates for pharmaceutical research. Numerous studies have isolated various algal polysaccharides possessing antiviral activities, including carrageenan, alginate, fucan, laminaran, and naviculan. In addition, different mechanisms of action have been reported for these polysaccharides, such as inhibiting the binding or internalization of virus into the host cells or suppressing DNA replication and protein synthesis. This review strives for compiling previous antiviral studies of algae-derived polysaccharides and their mechanism of action towards their development as natural antiviral agents for future investigations.
Rapid identification and source-tracking of Listeria monocytogenes using MALDI-TOF mass spectrometry.

Science.gov (United States)

Jadhav, Snehal; Gulati, Vandana; Fox, Edward M; Karpe, Avinash; Beale, David J; Sevior, Danielle; Bhave, Mrinal; Palombo, Enzo A

2015-06-02

Listeria monocytogenes is an important foodborne pathogen responsible for the sometimes fatal disease listeriosis. Public health concerns and stringent regulations associated with the presence of this pathogen in food and food processing environments underline the need for rapid and reliable detection and subtyping techniques. In the current study, the application of matrix assisted laser desorption/ionisation-time-of-flight mass spectrometry (MALDI-TOF MS) as a single identification and source-tracking tool for a collection of L. monocytogenes isolates, obtained predominantly from dairy sources within Australia, was explored. The isolates were cultured on different growth media and analysed using MALDI-TOF MS at two incubation times (24 and 48 h). Whilst reliable genus-level identification was achieved from most media, identification at the species level was found to be dependent on culture conditions. Successful speciation was highest for isolates cultured on the chromogenic Agar Listeria Ottaviani Agosti agar (ALOA, 91% of isolates) and non-selective horse blood agar (HBA, 89%) for 24h. Chemometric statistical analysis of the MALDI-TOF MS data enabled source-tracking of L. monocytogenes isolates obtained from four different dairy sources. Strain-level discrimination was also observed to be influenced by culture conditions. In addition, t-test/analysis of variance (ANOVA) was used to identify potential biomarker peaks that differentiated the isolates according to their source of isolation. Source-tracking using MALDI-TOF MS was compared and correlated with the gold standard pulsed-field gel electrophoresis (PFGE) technique. The discriminatory index and the congruence between both techniques were compared using the Simpsons Diversity Index and adjusted Rand and Wallace coefficients. Overall, MALDI-TOF MS based source-tracking (using data obtained by culturing the isolates on HBA) and PFGE demonstrated good congruence with a Wallace coefficient of 0.71 and
Isolation and screening of glycolipid biosurfactant producers from sugarcane.

Science.gov (United States)

Morita, Tomotake; Fukuoka, Tokuma; Imura, Tomohiro; Hirose, Naoto; Kitamoto, Dai

2012-01-01

Forty-three fungal producers for glycolipid biosurfactants, mannosylerythritol lipids (MELs), were isolated from leaves and smuts of sugarcane plants. These isolates produced MELs with sugarcane juice as nutrient source. The strains were taxonomically categorized into the genera Pseudozyma and Ustilago on the basis of partial sequences of the ribosomal RNA gene.

Pregnancy rate evaluation in lactating and non-lactating Nelore cows subjected to fixed-time artificial insemination using injectable progesterone

Directory of Open Access Journals (Sweden)

Jefferson Tadeu Campos

2016-08-01

Full Text Available Most fixed-time artificial insemination (FTAI protocols utilize progesterone (P4 as a hormonal source to achieve synchronization of estrus in cattle. The use of an injectable P4 source to control estrus would be an interesting pharmacological strategy owing to the practicality of parenteral application. However, the effects of injectable P4 on estrus cycle control in cattle remain poorly studied. In particular, no existing studies have investigated the effect of injectable P4 on the fertility of cows subjected to FTAI. The aim of this study was to evaluate the pregnancy rate of lactating and non-lactating Nelore cows subjected to FTAI with injectable P4. Of the 422 non-lactating cows in this study, 162 (38.3% became pregnant by 60 days post-FTAI. In the lactating group (n = 516, 166 (32.1% were pregnant by 60 days after treatment with injectable P4. The proportions of lactating and non-lactating cows becoming pregnant were compared using the chi-square test, adopting a significance level of P < 0.05. It was found that the pregnancy rate of the cows subjected to FTAI with injectable P4 was influenced by lactation status. Lactating cows had lower reproductive performance, possibly because of their higher nutritional requirements. However, the use of injectable P4 shows promising results and may prove to be a useful strategy in large-scale livestock production.
Source of Gallium-67 in gastrointestinal contents: concise communication

International Nuclear Information System (INIS)

Chen, D.C.; Scheffel, U.; Camargo, E.E.; Tsan, M.F.

1980-01-01

The sources of Ga-67 in gastrointestinal (GI) contents, and factors affecting its secretion were studied in rats. To prevent loss of fecal Ga-67, the anus was sutured before intravenous injection of Ga-67 citrate. Secretion of Ga-67 into the contents of the GI tract was rapid, 3, 6, and 9% of the injected dose were secreted at 1, 6, and 24 hr after injection, respectively. In contrast, Ga-67 concentration in the GI tissues remained relatively constant throughout this period. Analysis of Ga-67 contents of various parts of the GI tract revealed that small intestine is its major source, contributing 60% while the bile contributes 20%, large intestine 10%, esophagus and stomach 10%. Feeding had no effect on the Ga-67 secretion into GI contents. In contrast, the serum unbound iron-binding capacity (UIBC) played an important role in the GI secretion of Ga-67; reducing the serum UIBC reduced the Ga-67 secretion into GI contents
Therapeutic hip injections: Is the injection volume important?

International Nuclear Information System (INIS)

Young, R.; Harding, J.; Kingsly, A.; Bradley, M.

2012-01-01

Aim: To assess whether an increased volume of local anaesthetic injection given with intra-articular steroids improves symptom relief in osteoarthritis of the hip. Materials and methods: One hundred and ten patients with hip osteoarthritis were randomized into two groups (A and B). All patients were given 40 mg triamcinolone and 2 ml bupivicaine, and patients from group B were also given 6 ml of sterile water for injection. Change in WOMAC (Western Ontario and McMaster University Osteoarthritis Index Version 3.1) scores from baseline to 3 months were calculated and assessed for clinical and statistical significance. The patients were assessed for pain at 2 weekly intervals using the Oxford pain chart. Results: Patients from group B showed some reduction in stiffness (7%) and improved function (3%) compared with group A, and there were more clinical responders in these two categories. However, there was no significant statistical or clinical difference in WOMAC scores between the two groups at 3 months. There was also no statistical difference in pain symptoms between the two groups during the study period, measured at 2 weekly intervals. One hundred and two patients reached the study endpoint; eight patients who had bilateral hip injections were subsequently included in the analysis, and these patients did not alter the findings significantly. Conclusions: Published total injection volumes used for treating osteoarthritis of the hip with intra-articular steroids vary from 3 to 12 ml. The present study has shown that there is no detriment to using a larger volume of injectate, and recommends that practitioners use total volumes between 3 and 9 ml.
Therapeutic hip injections: Is the injection volume important?

Energy Technology Data Exchange (ETDEWEB)

Young, R., E-mail: russell.young@gwh.nhs.uk [Department of Radiology, Great Western Hospital, Swindon (United Kingdom); Harding, J. [Department of Radiology, University Hospital Coventry, Coventry (United Kingdom); Kingsly, A. [Department of Mathematics and Statistics, Bristol Institue of Technology, University of the West of England, Bristol (United Kingdom); Bradley, M. [Department of Radiology, Southmead Hospital, Bristol (United Kingdom)

2012-01-15

Aim: To assess whether an increased volume of local anaesthetic injection given with intra-articular steroids improves symptom relief in osteoarthritis of the hip. Materials and methods: One hundred and ten patients with hip osteoarthritis were randomized into two groups (A and B). All patients were given 40 mg triamcinolone and 2 ml bupivicaine, and patients from group B were also given 6 ml of sterile water for injection. Change in WOMAC (Western Ontario and McMaster University Osteoarthritis Index Version 3.1) scores from baseline to 3 months were calculated and assessed for clinical and statistical significance. The patients were assessed for pain at 2 weekly intervals using the Oxford pain chart. Results: Patients from group B showed some reduction in stiffness (7%) and improved function (3%) compared with group A, and there were more clinical responders in these two categories. However, there was no significant statistical or clinical difference in WOMAC scores between the two groups at 3 months. There was also no statistical difference in pain symptoms between the two groups during the study period, measured at 2 weekly intervals. One hundred and two patients reached the study endpoint; eight patients who had bilateral hip injections were subsequently included in the analysis, and these patients did not alter the findings significantly. Conclusions: Published total injection volumes used for treating osteoarthritis of the hip with intra-articular steroids vary from 3 to 12 ml. The present study has shown that there is no detriment to using a larger volume of injectate, and recommends that practitioners use total volumes between 3 and 9 ml.
78 FR 23246 - Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for...

Science.gov (United States)

2013-04-18

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9804-8] Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for Exemption--Class I Hazardous Waste Injection; BASF... exemption to the land disposal Restrictions, under the 1984 Hazardous and Solid Waste [[Page 23247...
Efficient Spin Injection into Semiconductor

International Nuclear Information System (INIS)

Nahid, M.A.I.

2010-06-01

Spintronic research has made tremendous progress nowadays for making future devices obtain extra advantages of low power, and faster and higher scalability compared to present electronic devices. A spintronic device is based on the transport of an electron's spin instead of charge. Efficient spin injection is one of the very important requirements for future spintronic devices. However, the effective spin injection is an exceedingly difficult task. In this paper, the importance of spin injection, basics of spin current and the essential requirements of spin injection are illustrated. The experimental technique of electrical spin injection into semiconductor is also discussed based on the experimental experience. The electrical spin injection can easily be implemented for spin injection into any semiconductor. (author)
77 FR 26755 - Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for...

Science.gov (United States)

2012-05-07

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9669-6] Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for Exemption--Class I Hazardous Waste Injection; Diamond... reissuance of an exemption to the land disposal Restrictions, under the 1984 Hazardous and Solid Waste...
76 FR 55908 - Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for...

Science.gov (United States)

2011-09-09

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9461-5] Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for Exemption--Class I Hazardous Waste Injection; Great Lakes... of an exemption to the land disposal restrictions, under the 1984 Hazardous and Solid Waste...
76 FR 36129 - Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for...

Science.gov (United States)

2011-06-21

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9321-3] Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for Exemption--Class I Hazardous Waste Injection; ExxonMobil... disposal Restrictions, under the 1984 Hazardous and Solid Waste Amendments to the Resource Conservation and...
78 FR 42776 - Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for...

Science.gov (United States)

2013-07-17

... ENVIRONMENTAL PROTECTION AGENCY [FRL9834-8] Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for Exemption--Class I Hazardous Waste Injection; Blanchard Refining... disposal Restrictions, under the 1984 Hazardous and Solid Waste Amendments to the Resource Conservation and...
77 FR 52717 - Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for...

Science.gov (United States)

2012-08-30

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9724-1] Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for Exemption--Class I Hazardous Waste Injection; Cornerstone... exemption to the land disposal Restrictions, under the 1984 Hazardous and Solid Waste Amendments to the...
Economic and safe operation of isolated systems with significant contribution from renewable energy sources; Operacao economica e segura de sistemas isolados com grande penetracao de energias renovaveis

Energy Technology Data Exchange (ETDEWEB)

Matos, M.A. [Instituto de Engenharia de Sistemas e Computadores (INESC), Porto (Portugal); Vlachos, A; Androutsos, A. [NTUA, Atenas (Greece); Bakirtzis, T. [AUTH, Salonica (Greece); Gigantidou, A. [DEI, Heraklio (Greece). E-mail: mmatos@inescn.pt; avlachos@power.ece.ntua.gr; bakiana@eng.auth.gr; deh_kkf@iraklio.netor.gr

1999-07-01

Medium and large size isolated systems with a significant contribution from renewable energy sources, specifically eolic energy, are not conveniently operated at the present, neither by the conventional ways of unit commitment/load dispatcher nor by the simplified procedures used in the small isolated power networks. This paper presents a new approaching, in the CARE framework which is financially supported by the European Union through the EEN-JOULE assistance program. The principal idea is to perform unit commitment on-line in the same dispatching cycle, by using the load forecasting and the more recent wind power. The process includes dynamic safety fast evaluation and a module for helping the decision making.
Statistical Analysis of Interchange Injection Events from Over a Decade of Cassini Data

Science.gov (United States)

Azari, A.; Jia, X.; Liemohn, M. W.; Sergis, N.; Thomsen, M. F.; Mitchell, D. G.; Rymer, A. M.; Paranicas, C.; Provan, G.; Ye, S.; Cowley, S. W. H.; Hospodarsky, G. B.; Vandegriff, J. D.; Kurth, W. S.

2017-12-01

The Cassini spacecraft has routinely observed interchange injection events with multiple instruments since arriving at Saturn in 2004. Interchange injection events are thought to initiate from a Rayleigh-Taylor like plasma instability sourced from Saturn's rapid rotation (period 10.8 hours) and dense plasma population outgassing primarily from Enceladus, and are the primary source of mass transport in the inner/middle magnetosphere. This dense plasma must be transported outward, and to conserve magnetic flux, inward moving flux tubes of low density, energetic (> keV) plasma from the outer reaches of the Saturnian system also occur. These inward-bound flux tubes are referred to as interchange injections. We will present a statistical evaluation of the occurrence rates of interchange injections at Saturn demonstrating seasonal dependence of interchange over the entirety of the Cassini mission's equatorial orbits between 2005 and 2016. We identify interchange events from CHarge Energy Mass Spectrometer (CHEMS) H+ data using a trained and tested automated algorithm. Our event identification compares well with manual identification and previous surveys of injections by L-shell and local time (Chen and Hill, 2008, Lai et al., 2016, Kennelly et al., 2013). We find that peak rates of interchange events occur between 7 - 9 Saturn radii, in agreement with previous surveys. We also evaluate interchange by preferred local time sector and season, splitting our events into pre-equinox, equinox, and post - equinox time periods. We determine that over all seasons, nightside occurrence dominated as compared to dayside, but the preferred dayside sector shifts from pre-noon during equinox, to post-noon during post-equinox. We will further investigate seasonal dependence by presenting occurrence organized by the phase systems derived based on Saturn kilometric radiation (SKR) and magnetic field perturbations (PPO).
Intraarticular cortisone injection for osteoarthritis of the hip. Is it effective? Is it safe?

Science.gov (United States)

Kruse, David W

2008-12-01

Osteoarthritis of the hip is a significant source of morbidity in the elderly. Treatment guidelines are available for the management of hip osteoarthritis, but these do not address the application of intraarticular corticosteroid injection. The intraarticular injection of corticosteroid is used in the management of other large joint osteoarthritic diseases and is well studied in the knee, however, this data cannot be used to make sound clinical decisions regarding its use for hip osteoarthritis. There are also concerns regarding the safety of this modality. Review of the published literature reveals that there are eight trials examining the efficacy of intraarticular corticosteroid injection for hip osteoarthritis and of these only four are randomized controlled trials. In general, the available literature demonstrates a short-term reduction of pain with corticosteroid injection and is indicated for patients refractory to non-pharmacologic or analgesic and NSAID therapy. The use of radiologic-guidance is recommended and, with proper sterile technique, the risk of adverse outcomes is very low. Future randomized controlled trials are needed to further examine the efficacy and safety of intraarticular corticosteroid injection for hip osteoarthritis.
76 FR 42125 - Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for...

Science.gov (United States)

2011-07-18

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9440-3] Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for Exemption--Class I Hazardous Waste Injection; ConocoPhillips... Restrictions, under the 1984 Hazardous and Solid Waste Amendments to the Resource Conservation and Recovery Act...
78 FR 76294 - Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for...

Science.gov (United States)

2013-12-17

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9904-21-OW] Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for Exemption--Class I Hazardous Waste Injection; Mosaic... Restrictions, under the 1984 Hazardous and Solid Waste Amendments to the Resource Conservation and Recovery Act...
75 FR 60457 - Underground Injection Control Program Hazardous Waste Injection Restrictions; Petition for...

Science.gov (United States)

2010-09-30

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9208-4] Underground Injection Control Program Hazardous Waste Injection Restrictions; Petition for Exemption--Class I Hazardous Waste Injection Dow Chemical Company (DOW... 1984 Hazardous and Solid Waste Amendments to the Resource Conservation and Recovery Act have been...
Water quality considerations resulting in the impaired injectivity of water injection and disposal wells

International Nuclear Information System (INIS)

Bennion, D.B.; Thomas, F.B.; Imer, D.; Ma, T.

2000-01-01

An environmentally responsible way to improve hydrocarbon recovery is to maintain pressure by water injection. This is a desirable method because unwanted produced water from oil and gas wells can be re-injected into producing or disposal formations. The success of the operation, however, depends on injecting the necessary volume of water economically, below the fracture gradient pressure of the formation. Well placement, geometry and inherent formation quality and relative permeability characteristics are some of the many other factors which influence the success of any injection project. Poor injection or poor quality of disposal water can also compromise the injectivity for even high quality sandstone or carbonate formations. This would necessitate costly workovers and recompletions. This paper presented some leading edge diagnostic techniques and evaluation methods to determine the quality of injected water. The same techniques could be used to better understand the effect of potential contaminants such as suspended solids, corrosion products, skim/carryover oil and grease, scales, precipitates, emulsions, oil wet hydrocarbon agglomerates and many other conditions which cause injectivity degradation. 14 refs., 1 tab., 15 figs
Antibacterial properties of 2% lidocaine and reduced rate of endophthalmitis after intravitreal injection.

Science.gov (United States)

Tustin, Aaron; Kim, Stephen J; Chomsky, Amy; Hubbard, G Baker; Sheng, Jinsong

2014-05-01

To determine whether the application of subconjunctival 2% lidocaine/0.1% methylparaben for anesthesia may reduce rates of endophthalmitis after intravitreal (IVT) injection. We performed in vitro experiments to determine the antibacterial properties of 2% lidocaine/0.1% methylparaben (lidocaine) against causative organisms of endophthalmitis. Isolates of Staphylococcus aureus, Staphylococcus epidermidis, and Streptococcus viridans from patients with endophthalmitis were incubated with or without lidocaine. Aliquots (100 µL) were plated on Mueller-Hinton (S. aureus and S. epidermidis) or blood agar plates (S. viridans) at 0, 10, 30, 120, and 240 minutes, and colonies were counted after 24 hours. A retrospective review of 15,042 IVT injections was performed from January 2004 to February 2011 to determine the rate of endophthalmitis with or without application of subconjunctival lidocaine for anesthesia. Lidocaine demonstrated rapid bactericidal effects against all 3 organisms. After 10 minutes of exposure, there was approximately a 90% (P < 0.01), 95% (P < 0.001), and 92% (P < 0.001) reduction in colony forming units when compared with time 0 for S. aureus, S. epidermidis, and S. viridans, respectively. Complete elimination of colony forming units occurred at subsequent time points for each organism in contrast to logarithmic increase for control plates. There were a total of 0 cases of endophthalmitis of 6,853 IVT injections performed with subconjunctival lidocaine and 8 cases of endophthalmitis of 8,189 (0.1%) IVT injections performed with other methods of anesthesia (P = 0.03). Application of subconjunctival 2% lidocaine/0.1% methylparaben for anesthesia may reduce the incidence of endophthalmitis after IVT injection.
Sonoanatomy and injection technique of the iliolumbar ligament.

LENUS (Irish Health Repository)

Harmon, Dominic

2012-01-31

BACKGROUND: The iliolumbar ligament plays an important biomechanic role in anchoring the spine to the pelvic ring and stabilizing the sacroiliac joint. Iliolumbar syndrome is a back pain condition caused by pathology of the iliolumbar ligament. History and physical examination are important in the assessment of back pain, but they lack sufficient specificity. Injection of small volumes of local anesthetic into the structure considered to be the source of the pain (i.e. the iliolumbar ligament) increases the specificity of the diagnostic workup. OBJECTIVE: To describe an ultrasound - guided technique for injecting the iliolumbar ligament. STUDY DESIGN: Case report based on knowledge of topographic anatomy and sonoanatomy. SETTING: Outpatient clinic. METHODS: A patient with a clinical picture suggestive of iliolumbar syndrome was selected. An ultrasound-guided injection of the iliolumbar ligament with local anesthetic was performed. We recorded the patient\\'s subjective assessment of pain and the change in range of movement and pain scores during provocative tests. RESULTS: Following the injection, the patient\\'s pain score decreased, provocation tests became negative, and the range of movement increased. LIMITATIONS: Case report. Target specificity and dispersion of local anesthetic spread not confirmed with an independent technique (i.e. magnetic resonance imaging). CONCLUSIONS: Ultrasound guidance allows the selective deposition of small volumes of local anesthetic into structures believed to cause soft tissue back pain and thus to confirm or exclude the working diagnosis. Further studies are needed to confirm our conclusions and to prove the clinical feasibility of this technique.

Ion source and injector development

International Nuclear Information System (INIS)

Curtis, C.D.

1976-01-01

This is a survey of low energy accelerators which inject into proton linacs. Laboratories covered include Argonne, Brookhaven, CERN, Chalk River, Fermi, ITEP, KEK, Rutherford, and Saclay. This paper emphasizes complete injector systems, comparing significant hardware features and beam performance data, including recent additions. There is increased activity now in the acceleration of polarized protons, H + and H - , and of unpolarized H - . New source development and programs for these ion beams is outlined at the end of the report. Heavy-ion sources are not included
Reduction of exposure of pet staff by computer-aided injection of radiotracers

International Nuclear Information System (INIS)

Balduyck, S.; Sarracanie, M.; Trevisan, L.

2006-01-01

Full text of publication follows: Positron Emission Tomograph y (PET) is now widely used, and everyday employment of positron emitters have brought new needs for radiation protection. Analysing the dosimetry of PET staff in the course of medical examinations, it was shown that the injection step is the most irradiating part. The necessity to monitor the safety of the patient during the injection of the radiotracer prevents us from reducing exposure time or to insert a complete shielding between the source and the operator. To lower the dose by increasing the distance, we designed a system based on two syringe pumps: one for the tracer and one for saline solution. Both a re remotely controlled by computer. The exposure of staff during the injection step is thus reduced to the five seconds necessary to place the shielded syringe in the pump. The sequence of injection is fully automatic, but all relevant parameters (such as pressure, volume, flow, occlusion detection, etc...) are continuously monitored and the operator can safely interrupt the sequence at any time. A visual, dialogue-based, interface has been designed to provide a convenient full monitoring service even for non-familiar computer users, without lowering the security of the patient. With this computer-aided injection system, the mean dose of exposure to PET staff was divided by eight. Such a system can be used in all radiopharmaceutical injections encountered in nuclear medicine or radiotherapy facilities, by adapting the injection sequence and the number of syringe pumps. (authors)
Calcitonin Salmon Injection

Science.gov (United States)

Calcitonin salmon injection is used to treat osteoporosis in postmenopausal women. Osteoporosis is a disease that causes bones to weaken and break more easily. Calcitonin salmon injection is also used to treat Paget's disease ...
Lightning Pin Injection Testing on MOSFETS

Science.gov (United States)

Ely, Jay J.; Nguyen, Truong X.; Szatkowski, George N.; Koppen, Sandra V.; Mielnik, John J.; Vaughan, Roger K.; Wysocki, Philip F.; Celaya, Jose R.; Saha, Sankalita

2009-01-01

Lightning transients were pin-injected into metal-oxide-semiconductor field-effect transistors (MOSFETs) to induce fault modes. This report documents the test process and results, and provides a basis for subsequent lightning tests. MOSFETs may be present in DC-DC power supplies and electromechanical actuator circuits that may be used on board aircraft. Results show that unprotected MOSFET Gates are susceptible to failure, even when installed in systems in well-shielded and partial-shielded locations. MOSFET Drains and Sources are significantly less susceptible. Device impedance decreased (current increased) after every failure. Such a failure mode may lead to cascading failures, as the damaged MOSFET may allow excessive current to flow through other circuitry. Preliminary assessments on a MOSFET subjected to 20-stroke pin-injection testing demonstrate that Breakdown Voltage, Leakage Current and Threshold Voltage characteristics show damage, while the device continues to meet manufacturer performance specifications. The purpose of this research is to develop validated tools, technologies, and techniques for automated detection, diagnosis and prognosis that enable mitigation of adverse events during flight, such as from lightning transients; and to understand the interplay between lightning-induced surges and aging (i.e. humidity, vibration thermal stress, etc.) on component degradation.
3D Adaptive Mesh Refinement Simulations of Pellet Injection in Tokamaks

International Nuclear Information System (INIS)

Samtaney, S.; Jardin, S.C.; Colella, P.; Martin, D.F.

2003-01-01

We present results of Adaptive Mesh Refinement (AMR) simulations of the pellet injection process, a proven method of refueling tokamaks. AMR is a computationally efficient way to provide the resolution required to simulate realistic pellet sizes relative to device dimensions. The mathematical model comprises of single-fluid MHD equations with source terms in the continuity equation along with a pellet ablation rate model. The numerical method developed is an explicit unsplit upwinding treatment of the 8-wave formulation, coupled with a MAC projection method to enforce the solenoidal property of the magnetic field. The Chombo framework is used for AMR. The role of the E x B drift in mass redistribution during inside and outside pellet injections is emphasized
UV-visible digital imaging of split injection in a Gasoline Direct Injection engine

Directory of Open Access Journals (Sweden)

Merola Simona Silvia

2015-01-01

Full Text Available Ever tighter limits on pollutant emissions and the need to improve energy conversion efficiency have made the application of gasoline direct injection (GDI feasible for a much wider scale of spark ignition engines. Changing the way fuel is delivered to the engine has thus provided increased flexibility but also challenges, such as higher particulate emissions. Therefore, alternative injection control strategies need to be investigated in order to obtain optimum performance and reduced environmental impact. In this study, experiments were carried out on a single-cylinder GDI optical engine fuelled with commercial gasoline in lean-burn conditions. The single-cylinder was equipped with the head of a commercial turbocharged engine with similar geometrical specifications (bore, stroke, compression ratio and wall guided fuel injection. Optical accessibility was ensured through a conventional elongated hollow Bowditch piston and an optical crown, accommodating a fused-silica window. Experimental tests were performed at fixed engine speed and injection pressure, whereas the injection timing and the number of injections were adjusted to investigate their influence on combustion and emissions. UV-visible digital imaging was applied in order to follow the combustion process, from ignition to the late combustion phase. All the optical data were correlated with thermodynamic analysis and measurements of exhaust emissions. Split injection strategies (i.e. two injections per cycle with respect to single injection increased combustion efficiency and stability thanks to an improvement of fuel air mixing. As a consequence, significant reduction in soot formation and exhaust emission with acceptable penalty in terms of HC and NOx were measured.
Deoxycholic Acid Injection

Science.gov (United States)

Deoxycholic acid injection is used to improve the appearance and profile of moderate to severe submental fat ('double chin'; fatty tissue located under the chin). Deoxycholic acid injection is in a class of medications called ...
Antigen injection (image)

Science.gov (United States)

Leprosy is caused by the organism Mycobacterium leprae . The leprosy test involves injection of an antigen just under ... if your body has a current or recent leprosy infection. The injection site is labeled and examined ...
Injection of tennis elbow: Hit and miss? A cadaveric study of injection accuracy

NARCIS (Netherlands)

Keijsers, Renee; van den Bekerom, Michel P. J.; Koenraadt, Koen L. M.; Bleys, Ronald L. A. W.; van Dijk, C. Niek; Eygendaal, Denise; van Riet, Roger; Middernacht, Bart; Defoort, Saartje; Wagener, Marc; Harake, Ramzi; Ciornohac, Jean-Florin; Montarnal, Robert; van Benthem, Yasmin; Cattaneo, Stefano; Faber, Dirk; Galatz, Leesa; Birkisson, Illugi; van der Hoeven, Henk; Witjes, Suzanne; Heeren, M.; Ahmed, El-Gammal; Husif, N. N.; Beumer, Annechien; The, Bertram

2017-01-01

Different injection therapies are used in the treatment of lateral epicondylitis (LE). Usually, the extensor carpi radialis brevis (ECRB) tendon is affected. Therefore, an injection should be aimed at the origin of this tendon. This study demonstrates the accuracy of manual injections in the
Iron Dextran Injection

Science.gov (United States)

Iron dextran injection is used to treat iron-deficiency anemia (a lower than normal number of red blood cells ... treated with iron supplements taken by mouth. Iron dextran injection is in a class of medications called ...
Aminocaproic Acid Injection

Science.gov (United States)

Aminocaproic acid injection is used to control bleeding that occurs when blood clots are broken down too quickly. This ... the baby is ready to be born). Aminocaproic acid injection is also used to control bleeding in ...
Cluster beam injection

International Nuclear Information System (INIS)

Bottiglioni, F.; Coutant, J.; Fois, M.

1978-01-01

Areas of possible applications of cluster injection are discussed. The deposition inside the plasma of molecules, issued from the dissociation of the injected clusters, has been computed. Some empirical scaling laws for the penetration are given
The Advanced Photon Source list of parameters

International Nuclear Information System (INIS)

Bizek, H.M.

1996-07-01

The Advanced Photon Source (APS) is a third-generation synchrotron radiation source that stores positrons in a storage ring. The choice of positrons as accelerating particles was motivated by the usual reason: to eliminate the degradation of the beam caused by trapping of positively charged dust particles or ions. The third-generation synchrotron radiation sources are designed to have low beam emittance and many straight sections for insertion devices. The parameter list is comprised of three basic systems: the injection system, the storage ring system, and the experimental facilities system. The components of the injection system are listed according to the causal flow of positrons. Below we briefly list the individual components of the injection system, with the names of people responsible for managing these machines in parentheses: the linac system; electron linac-target-positron linac (Marion White); low energy transport line from linac to the PAR (Michael Borland); positron accumulator ring or PAR (Michael Borland); low energy transport line from PAR to injector synchrotron (Michael Borland); injector synchrotron (Stephen Milton); high energy transport line from injector synchrotron to storage ring (Stephen Milton). The storage ring system, managed by Glenn Decker, uses the Chasman-Green lattice. The APS storage ring, 1104 m in circumference, has 40 periodic sectors. Six are used to house hardware and 34 serve as insertion devices. Another 34 beamlines emit radiation from bending magnets. The experimental facilities system's parameters include parameters for both an undulator and a wiggler
Antimicrobial properties of probiotic bacteria from various sources ...

African Journals Online (AJOL)

The probiotic potentials of lactic acid bacteria species isolated from various food sources (nono, ugba, ogiri, kunun-zaki and ogi) were studied. The predominant species among the isolated strains were Lactobacillus bulgaricus, Lactobacillus fermentum, Lactobacillus plantarum, Lactobacillus brevis, Streptococcus ...
Surgical versus injection treatment for injection-confirmed chronic sacroiliac joint pain

Science.gov (United States)

Spiker, William Ryan; Lawrence, Brandon D.; Raich, Annie L.; Skelly, Andrea C.; Brodke, Darrel S.

2012-01-01

Study design: Systematic review. Study rationale: Chronic sacroiliac joint pain (CSJP) is a common clinical entity with highly controversial treatment options. A recent systematic review compared surgery with denervation, but the current systematic review compares outcomes of surgical intervention with therapeutic injection for the treatment of CSJP and serves as the next step for evaluating current evidence on the comparative effectiveness of treatments for non-traumatic sacroiliac joint pain. Objective or clinical question: In adult patients with injection-confirmed CSJP, does surgical treatment lead to better outcomes and fewer complications than injection therapy? Methods: A systematic review of the English-language literature was undertaken for articles published between 1970 and June 2012. Electronic databases and reference lists of key articles were searched to identify studies evaluating surgery or injection treatment for injection-confirmed CSJP. Studies involving traumatic onset or non-injection–confirmed CSJP were excluded. Two independent reviewers assessed the level of evidence quality using the grading of recommendations assessment, development and evaluation (GRADE) system, and disagreements were resolved by consensus. Results: We identified twelve articles (seven surgical and five injection treatment) meeting our inclusion criteria. Regardless of the type of treatment, most studies reported over 40% improvement in pain as measured by Visual Analog Scale or Numeric rating Scale score. Regardless of the type of treatment, most studies reported over 20% improvement in functionality. Most complications were reported in the surgical studies. Conclusion: Surgical fusion and therapeutic injections can likely provide pain relief, improve quality of life, and improve work status. The comparative effectiveness of these interventions cannot be evaluated with the current literature. PMID:23526911
On-line dynamic extraction and automated determination of readily bioavailable hexavalent chromium in solid substrates using micro-sequential injection bead-injection lab-on-valve hyphenated with electrothermal atomic absorption spectrometry

DEFF Research Database (Denmark)

Long, Xiangbao; Miró, Manuel; Hansen, Elo Harald

2006-01-01

A novel and miniaturized micro-sequential injection bead injection lab-on-valve (μSI-BI-LOV) fractionation system was developed for in-line microcolumn soil extraction under simulated environmental scenarios and accurate monitoring of the content of easily mobilisable hexavalent chromium in soil...... environments at the sub-low parts-per-million level. The flow system integrates dynamic leaching of hexavalent chromium using deionized water as recommended by the German Standard DIN 38414-S4 method; on-line pH adjustment of the extract by a 0.01 mol L-1 Tris-HNO3 buffer solution; isolation of the chromate...... polluted agricultural soil material (San Joaquin Soil-Baseline Trace Element Concentrations) with water-soluble Cr(VI) salts at different concentration levels. The potential of the μSI-BI-LOV set-up with renewable surfaces for flame-AAS determination of high levels of readily bioavailable chromate...
Injection Technique and Pen Needle Design Affect Leakage From Skin After Subcutaneous Injections

DEFF Research Database (Denmark)

Præstmark, Kezia Ann; Stallknecht, Bente; Jensen, Morten Lind

2016-01-01

BACKGROUND: After a subcutaneous injection fluid might leak out of the skin, commonly referred to as leakage or backflow. The objective was to examine the influence of needle design and injection technique on leakage after injections in the subcutaneous tissue of humans and pigs. METHOD: Leakage ...
Bacteriological and virulence study of a Mycobacterium chimaera isolate from a patient in China.

Science.gov (United States)

Liu, Guan; Chen, Su-Ting; Yu, Xia; Li, Yu-Xun; Ling, Ying; Dong, Ling-Ling; Zheng, Su-Hua; Huang, Hai-Rong

2015-04-01

A clinical isolate from a patient was identified as Mycobacterium chimaera, a recently identified species of nontuberculous Mycobacteria. The biochemical and molecular identity, drug sensitivity and virulence of this isolated strain were investigated. 16S rRNA, the 16S-23S ITS, hsp65 and rpoB were amplified, and their sequence similarities with other mycobacteria were analyzed. The minimum inhibitory concentrations of 22 anti-microbial agents against this isolate were established, and the virulence of the isolate was evaluated by intravenous injection into C57BL/6 mice using Mycobacterium tuberculosis H37Rv as a control strain. Growth and morphological characteristics and mycolic acid profile analysis revealed that this isolated strain was a member of the Mycobacterium avium complex. BLAST analysis of the amplified sequences showed that the isolated strain was closely related to M. chimaera. Susceptibility testing showed that the isolate was sensitive to rifabutin, rifapentine, clarithromycin, azithromycin, imipenem and cefoxitin. Bacterial load determination and tissue histopathology of the infected mice indicated that the isolate was highly virulent. The first case of M. chimaera infection in China was evaluated. The information derived from this case may offer valuable guidance for clinical diagnosis and treatment.
Deposition probe measurements of impurities injected into a tokamak plasma

International Nuclear Information System (INIS)

Hildebrandt, D.; Grote, H.; Herrmann, A.

1985-01-01

Impurity confinement behaviour has been studied by using a deposition probe in conjunction with pellet injection. Generally, an exponential decay of the impurity efflux and nearly symmetric ion/electron side toroidal flows have been observed. During phases of strong plasma disturbances, asymmetric flow is seen, indicative of edge transport and prompt recycling from local sources. The application of ECRH may cause such disturbances. (author)
Evidence for neutral beam injected oxygen impurities in 2XIIB

International Nuclear Information System (INIS)

Drake, R.P.; Moos, H.W.

1978-01-01

A series of experiments indicates that the principal source of impurities in the 2XIIB mirror confinement plasma experiment at Lawrence Livermore Laboratory is oxygen in the neutral beams. The dependence of 0 II 539 A emissions on neutral beam current, spatial scans of oxygen emissions, impurity injection experiments, spectral scans of the 0 VI 1032 A line, and other experiments all support this conclusion

Screening of Local Bacillus thuringiensis Isolates for Toxicity to ...

African Journals Online (AJOL)

Stem borers are a major source of pre-harvest maize crop losses in Kenya and many Sub- Saharan African countries. This menace needs to be addressed if food security is to be realized in this region. Seven local isolates of Bacillus thuringiensis (Bt) strains were isolated from soils collected from Kakamega and Machakos ...
Application of new pre-isolation techniques to mode cleaner design

Energy Technology Data Exchange (ETDEWEB)

Barriga, Pablo [School of Physics, University of Western Australia, Crawley, WA 6009 (Australia); Woolley, Andrew [School of Physics, University of Western Australia, Crawley, WA 6009 (Australia); Zhao Chunnong [Computer and Information Science, Edith Cowan University, Mount Lawley, WA 6050 (Australia); Blair, David G [School of Physics, University of Western Australia, Crawley, WA 6009 (Australia)

2004-03-07

Two very low frequency pre-isolation stages can greatly reduce the residual motion of suspended optical components. In a mode cleaner this can reduce the control forces required on the mirrors, simplifying lock acquisition and reducing noise injection through control forces. This paper describes a 12 m triangular suspended mode cleaner under construction for the AIGO high optical power interferometer. A novel and very compact multistage isolator supports the cavity mirrors. It combines an inverse pendulum in series with a low-mass Roberts linkage, both with pendulum frequencies below 0.1 Hz. The suspension chain is connected to the Roberts linkage via a Euler spring stage and a cantilever spring assembly for vertical isolation. We present an analysis of the mode cleaner, emphasizing the advantage of the improved mode-cleaner suspension and its power-handling capability. The effect of seismic noise on the residual velocity of the mirrors and the predicted frequency stability of the optical cavity are presented.
Application of new pre-isolation techniques to mode cleaner design

International Nuclear Information System (INIS)

Barriga, Pablo; Woolley, Andrew; Zhao Chunnong; Blair, David G

2004-01-01

Two very low frequency pre-isolation stages can greatly reduce the residual motion of suspended optical components. In a mode cleaner this can reduce the control forces required on the mirrors, simplifying lock acquisition and reducing noise injection through control forces. This paper describes a 12 m triangular suspended mode cleaner under construction for the AIGO high optical power interferometer. A novel and very compact multistage isolator supports the cavity mirrors. It combines an inverse pendulum in series with a low-mass Roberts linkage, both with pendulum frequencies below 0.1 Hz. The suspension chain is connected to the Roberts linkage via a Euler spring stage and a cantilever spring assembly for vertical isolation. We present an analysis of the mode cleaner, emphasizing the advantage of the improved mode-cleaner suspension and its power-handling capability. The effect of seismic noise on the residual velocity of the mirrors and the predicted frequency stability of the optical cavity are presented
Colicinogeny in Salmonella serovars isolated in Brazil

Directory of Open Access Journals (Sweden)

Leila Carvalho Campos

1988-06-01

Full Text Available A study of colicinogeny was made in 748 strains of Salmonella (97 serovars isolated from different sources; human (291, animal (119, environmental (141, food (102 and animal feed (95. Colicin production was detected in 64 strains (8.6%, particularly isolated from foods (30.4%. Col. E1 (53 and Ia (44 were the most frequently observed, especially in S. agona for environment and food sources. Col V production was identified in 5 strains of S. typhimurium within 8 producer cultures isolated from humans. Its relationship with the sources and serovars of Salmonella are discussed.Investigou-se a produção de colicina em 748 amostras de Salmonella (97 sorovares advindas de díferentes fontes: humana (291, animal (119, ambiental (141, de alimentos (102 e rações (95. Detectaram-se 64 amostras (8,6% colicinogênicas, particularmente isoladas de alimentos (30,4%. ColE1 (53 e Ia (44 foram as mais freqüentes, especialmente no sorovar S, agona, de origem ambiental e de alimentos. Identificou-se também a produção de col V em 5 amostras de S. typhimurium dentre 8 culturas produtoras de origem humana. Discute-se a relação entre a capacidade colicinogênica e as fontes e sorovares de Salmonella.
The development of new injection septum magnet for upgrating of J-PARC MR (3)

International Nuclear Information System (INIS)

Shibata, Tatsunobu; Ishii, Koji; Sugimoto, Takuya; Matsumoto, Noriyuki; Matsumoto, Hiroshi; Fan, Kuanjun; Kawaguchi, Yusuke; Nakamura, Kenta; Hamano, Kei

2017-01-01

We are improving the Main Ring (MR) for beam power of 750 kW which is a first goal of J-PARC. The repetition period of the Fast eXtraction(FX) must be shorten to 1.3 sec from the current period of 2.48 sec for the improvement of the beam power. We must upgrade injection and extraction magnets and their power supplies for upgrading the beam power. In 2016 summer, we have finished the replacement of a high field injection septum magnet and its power supply. One of the main reason was that the previous injection septum system could not be operated with 1.3 sec repetition. The other thing was that we have confirmed the large leakage field around circulating beam line of the injection magnet, so we must reduce them. The new injection septum magnet and its power supply were produced in 2014. We started to conduct the test-operation of the power supply and measurement of the magnetic field in 2015, and finished in August 2016, We have started the beam operation with the new injection septum in October 2016. The converter units in the new power supply of the new injection septum were broken in October and November 2016 as initial trouble. The main source of the trouble was electric noise in the gate signal. After countermeasure, we have no trouble in the power supply. We have found that there is still small leakage field in the upstream line of the new injection septum. We have installed an additional magnetic shield to the new injection septum. (author)
Multi-shot type pellet injection device

International Nuclear Information System (INIS)

Onozuka, Masaki; Uchikawa, Takashi; Kuribayashi, Shitomi.

1988-01-01

Purpose: To inject pellets at high speed without melting or sublimating not-injected pellets even at a long pellet injection interval. Constitution: In the conventional multi-shot pellet injection device, the pellet injection interval is set depending on the plasma retention time. However, as the pellet injection interval is increased, not-injected pellets are melted or sublimated due to the introduced heat of acceleration gases supplied from an acceleration gas introduction pipe to give an effect on the dimensional shape of the pellets. In view of the above, a plurality of pellet forming and injection portions each comprising a carrier, an injection pipe and a holder are disposed independently of each other and pellets are formed and injected independently to thereby prevent the thermal effects of the acceleration gases. (Kamimura, M.)
Multi-shot type pellet injection device

Energy Technology Data Exchange (ETDEWEB)

Onozuka, Masaki; Uchikawa, Takashi; Kuribayashi, Shitomi.

1988-07-27

Purpose: To inject pellets at high speed without melting or sublimating not-injected pellets even at a long pellet injection interval. Constitution: In the conventional multi-shot pellet injection device, the pellet injection interval is set depending on the plasma retention time. However, as the pellet injection interval is increased, not-injected pellets are melted or sublimated due to the introduced heat of acceleration gases supplied from an acceleration gas introduction pipe to give an effect on the dimensional shape of the pellets. In view of the above, a plurality of pellet forming and injection portions each comprising a carrier, an injection pipe and a holder are disposed independently of each other and pellets are formed and injected independently to thereby prevent the thermal effects of the acceleration gases. (Kamimura, M.).
Syringe injectable electronics

Science.gov (United States)

Hong, Guosong; Zhou, Tao; Jin, Lihua; Duvvuri, Madhavi; Jiang, Zhe; Kruskal, Peter; Xie, Chong; Suo, Zhigang; Fang, Ying; Lieber, Charles M.

2015-01-01

Seamless and minimally-invasive three-dimensional (3D) interpenetration of electronics within artificial or natural structures could allow for continuous monitoring and manipulation of their properties. Flexible electronics provide a means for conforming electronics to non-planar surfaces, yet targeted delivery of flexible electronics to internal regions remains difficult. Here, we overcome this challenge by demonstrating syringe injection and subsequent unfolding of submicrometer-thick, centimeter-scale macroporous mesh electronics through needles with a diameter as small as 100 micrometers. Our results show that electronic components can be injected into man-made and biological cavities, as well as dense gels and tissue, with > 90% device yield. We demonstrate several applications of syringe injectable electronics as a general approach for interpenetrating flexible electronics with 3D structures, including (i) monitoring of internal mechanical strains in polymer cavities, (ii) tight integration and low chronic immunoreactivity with several distinct regions of the brain, and (iii) in vivo multiplexed neural recording. Moreover, syringe injection enables delivery of flexible electronics through a rigid shell, delivery of large volume flexible electronics that can fill internal cavities and co-injection of electronics with other materials into host structures, opening up unique applications for flexible electronics. PMID:26053995
Recommended management practices for operation and closure of shallow injection wells at DOE facilities

International Nuclear Information System (INIS)

1993-07-01

The Safe Drinking Water Act established the Underground Injection Control (UIC) program to ensure that underground injection of wastes does not endanger an underground source of drinking water. Under UIC regulations, an injection well is a hole in the ground, deeper than it is wide, that receives wastes or other fluid substances. Types of injection wells range from deep cased wells to shallow sumps, drywells, and drainfields. The report describes the five classes of UIC wells and summarizes relevant regulations for each class of wells and for the UIC program. The main focus of the report is Class IV and V shallow injection wells. Class IV wells are prohibited and should be closed when they are identified. Class V wells are generally authorized by rule, but EPA or a delegated state may require a permit for a Class V well. This report provides recommendations on sound operating and closure practices for shallow injection wells. In addition the report contains copies of several relevant EPA documents that provide additional information on well operation and closure. Another appendix contains information on the UIC programs in 21 states in which there are DOE facilities discharging to injection wells. The appendix includes the name of the responsible regulatory agency and contact person, a summary of differences between the state's regulations and Federal regulations, and any closure guidelines for Class IV and V wells
Isolation of antimicrobial producing Actinobacteria from soil samples.

Science.gov (United States)

Elbendary, Afaf Ahmed; Hessain, Ashgan Mohamed; El-Hariri, Mahmoud Darderi; Seida, Ahmed Adel; Moussa, Ihab Mohamed; Mubarak, Ayman Salem; Kabli, Saleh A; Hemeg, Hassan A; El Jakee, Jakeen Kamal

2018-01-01

Emergence of multidrug resistant bacteria has made the search for novel bioactive compounds from natural and unexplored habitats a necessity. Actinobacteria have important bioactive substances. The present study investigated antimicrobial activity of Actinobacteria isolated from soil samples of Egypt. One hundred samples were collected from agricultural farming soil of different governorates. Twelve isolates have produced activity against the tested microorganisms ( S. aureus , Bacillus cereus , E. coli , K. pneumoniae , P. aeruginosa , S. Typhi, C. albicans , A. niger and A. flavus ). By VITEK 2 system version: 07.01 the 12 isolates were identified as Kocuria kristinae , Kocuria rosea , Streptomyces griseus , Streptomyces flaveolus and Actinobacteria . Using ethyl acetate extraction method the isolates culture's supernatants were tested by diffusion method against indicator microorganisms. These results indicate that Actinobacteria isolated from Egypt farms could be sources of antimicrobial bioactive substances.
Computer-controlled data acquisition system for the ISX-B neutral injection system

International Nuclear Information System (INIS)

Edmonds, P.H.; Sherrill, B.; Pearce, J.W.

1980-05-01

A data acquisition system for the Impurity Study Experiment (ISX-B) neutral injection system at the Oak Ridge National Laboratory is presented. The system is based on CAMAC standards and is controlled by a MIK-11/2 microcomputer. The system operates at the ion source high voltage on the source table, transmitting the analyzed data to a terminal at ground potential. This reduces the complexity of the communications link and also allows much flexibility in the diagnostics and eventual control of the beam line
Isolation, identification and antagonistic activity evaluation of actinomycetes in barks of nine trees

Directory of Open Access Journals (Sweden)

Wang Dong-sheng

2017-01-01

Full Text Available Actinomycetes are important producers of novel bioactive compounds. New sources need to be explored for isolating previously unknown bioactive compound-producing actinomycetes. Here we evaluated the potential of bark as a natural source of novel bioactive actinomycete species. Bark samples were collected from nine tree species at different elevations (1600-3400 ma.s.l. on Qin Mountain, Shaanxi Province, China. Actinomycetes were cultivated, enumerated and isolated using serial dilution and spread-plate techniques. The antimicrobial activity of actinomycete isolates was analyzed using an agar block method against 15 typical bacterial and fungal species and plant pathogens. The dominant isolates were identified by 16S rRNA-based sequence analysis. Results showed that actinomycete counts in bark samples of Quercus liaotungensis Koidz. was the highest among all trees species tested. The numbers of actinomycete species in bark samples were highest in Q. aliena var. acutiserrata and Spiraea alpina Pall. Antagonistic activity wasdetected in approximately 54% of the actinomycete isolates. Of these, 20 isolates (25% showed broad-spectrum antagonistic activity against ≥5 of the microorganisms tested. In conclusion, the bark on coniferous and broadleaf trees possesses a high diversity of actinomycetes and serves as a natural source of bioactive compound-producing actinomycetes.
Source attribution of human campylobacteriosis in Denmark.

Science.gov (United States)

Boysen, L; Rosenquist, H; Larsson, J T; Nielsen, E M; Sørensen, G; Nordentoft, S; Hald, T

2014-08-01

SUMMARY This study assesses the contribution of different sources of human campylobacteriosis in Denmark using two different source-attribution approaches. In total, 794 non-human isolates and 406 isolates from human cases (domestic, travel related, and cases with unknown travel history) were collected. Isolates were characterized by multilocus sequence typing, flaA typing and susceptibility to antibiotics. Both models used indicate that the major burden of human campylobacteriosis in Denmark originates from the domestic broiler chicken reservoir. The second most important reservoir was found to be cattle. The Asymmetric Island model attributed 52% [95% credibility interval (CrI) 37-67] to Danish chicken, 17% (95% CrI 3-33) to imported chicken, and 17% (95% CrI 7-28) to cattle. Similarly, the Campylobacter source-attribution model apportioned 38% (95% CrI 28-47) to Danish chicken, 14% (95% CrI 10-18) to imported chicken, and 16% (95% CrI 7-25) to cattle. The addition of flaA type as an extra discriminatory typing parameter did not change the attribution of cases markedly.
Improvements to the internal and external antenna H(-) ion sources at the Spallation Neutron Source.

Science.gov (United States)

Welton, R F; Dudnikov, V G; Han, B X; Murray, S N; Pennisi, T R; Pillar, C; Santana, M; Stockli, M P; Turvey, M W

2014-02-01

The Spallation Neutron Source (SNS), a large scale neutron production facility, routinely operates with 30-40 mA peak current in the linac. Recent measurements have shown that our RF-driven internal antenna, Cs-enhanced, multi-cusp ion sources injects ∼55 mA of H(-) beam current (∼1 ms, 60 Hz) at 65-kV into a Radio Frequency Quadrupole (RFQ) accelerator through a closely coupled electrostatic Low-Energy Beam Transport system. Over the last several years a decrease in RFQ transmission and issues with internal antennas has stimulated source development at the SNS both for the internal and external antenna ion sources. This report discusses progress in improving internal antenna reliability, H(-) yield improvements which resulted from modifications to the outlet aperture assembly (applicable to both internal and external antenna sources) and studies made of the long standing problem of beam persistence with the external antenna source. The current status of the external antenna ion source will also be presented.
Cost-Utility of a Single-Injection Combined Corticosteroid-Hyaluronic Acid Formulation vs a 2-Injection Regimen of Sequential Corticosteroid and Hyaluronic Acid Injections.

Science.gov (United States)

Belzile, Etienne L; Deakon, Robert T; Vannabouathong, Christopher; Bhandari, Mohit; Lamontagne, Martin; McCormack, Robert

2017-01-01

Research has shown early and sustained relief with a combination therapy of a corticosteroid (CS) and hyaluronic acid (HA) in knee osteoarthritis (OA) patients. This can be administered via a single injection containing both products or as separate injections. The former may be more expensive when considering only product cost, but the latter incurs the additional costs and time of a second procedure. The purpose of this study was to compare the cost-utility of the single injection with the 2-injection regimen. The results of this analysis revealed that the single-injection formulation of a CS and HA may be cost-effective, assuming a willingness-to-pay of $50 000 per quality-adjusted life year gained, for symptomatic relief of OA symptoms. This treatment may also be more desirable to patients who find injections to be inconvenient or unpleasant.
High-Dose Vitamin C Injection to Cancer Patients May Promote Thrombosis Through Procoagulant Activation of Erythrocytes.

Science.gov (United States)

Kim, Keunyoung; Bae, Ok-Nam; Koh, Sung-Hee; Kang, Seojin; Lim, Kyung-Min; Noh, Ji-Yoon; Shin, Sue; Kim, Inho; Chung, Jin-Ho

2015-10-01

Potential risk of high-dose vitamin C consumption is often ignored. Recently, gram-dose vitamin C is being intravenously injected for the treatment of cancer, which can expose circulating blood cells to extremely high concentrations of vitamin C. As well as platelets, red blood cells (RBCs) can actively participate in thrombosis through procoagulant activation. Here, we examined the procoagulant and prothrombotic risks associated with the intravenous injection of gram-dose vitamin C. Vitamin C (0.5-5 mM) increased procoagulant activity of freshly isolated human RBCs via the externalization of phosphatidylserine (PS) to outer cellular membrane and the formation of PS-bearing microvesicles. PS exposure was induced by the dysregulation of key enzymes for the maintenance of membrane phospholipid asymmetry, which was from vitamin C-induced oxidative stress, and resultant disruption of calcium and thiol homeostasis. Indeed, the intravenous injection of vitamin C (0.5-1.0 g/kg) in rats in vivo significantly increased thrombosis. Notably, the prothrombotic effects of vitamin C were more prominent in RBCs isolated from cancer patients, who are at increased risks of thrombotic events. Vitamin C-induced procoagulant and prothrombotic activation of RBCs, and increased thrombosis in vivo. RBCs from cancer patients exhibited increased sensitivity to the prothrombotic effects of vitamin C, reflecting that intravenous gram-dose vitamin C therapy needs to be carefully revisited. © The Author 2015. Published by Oxford University Press on behalf of the Society of Toxicology. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
Profiles of antibiotic susceptibilities of bacterial isolates and physico ...

African Journals Online (AJOL)

The Venda region of South Africa is predominantly rural and residents rely on untreated water sources for daily water needs. The physico-chemical quality of these water sources including antibiotic susceptibilities of enteric bacterial isolates which would guide clinicians in the empiric management of diarrhoea have ...
Isolation, characterization and transcriptome analysis of a novel Antarctic Aspergillus sydowii strain MS-19 as a potential lignocellulosic enzyme source.

Science.gov (United States)

Cong, Bailin; Wang, Nengfei; Liu, Shenghao; Liu, Feng; Yin, Xiaofei; Shen, Jihong

2017-05-30

With the growing demand for fossil fuels and the severe energy crisis, lignocellulose is widely regarded as a promising cost-effective renewable resource for ethanol production, and the use of lignocellulose residues as raw material is remarkable. Polar organisms have important value in scientific research and development for their novelty, uniqueness and diversity. In this study, a fungus Aspergillus sydowii MS-19, with the potential for lignocellulose degradation was screened out and isolated from an Antarctic region. The growth profile of Aspergillus sydowii MS-19 was measured, revealing that Aspergillus sydowii MS-19 could utilize lignin as a sole carbon source. Its ability to synthesize low-temperature lignin peroxidase (Lip) and manganese peroxidase (Mnp) enzymes was verified, and the properties of these enzymes were also investigated. High-throughput sequencing was employed to identify and characterize the transcriptome of Aspergillus sydowii MS-19. Carbohydrate-Active Enzymes (CAZyme)-annotated genes in Aspergillus sydowii MS-19 were compared with those in the brown-rot fungus representative species, Postia placenta and Penicillium decumbens. There were 701CAZymes annotated in Aspergillus sydowii MS-19, including 17 cellulases and 19 feruloyl esterases related to lignocellulose-degradation. Remarkably, one sequence annotated as laccase was obtained, which can degrade lignin. Three peroxidase sequences sharing a similar structure with typical lignin peroxidase and manganese peroxidase were also found and annotated as haem-binding peroxidase, glutathione peroxidase and catalase-peroxidase. In this study, the fungus Aspergillus sydowii MS-19 was isolated and shown to synthesize low-temperature lignin-degrading enzymes: lignin peroxidase (Lip) and manganese peroxidase (Mnp). These findings provide useful information to improve our understanding of low-temperature lignocellulosic enzyme production by polar microorganisms and to facilitate research and
Preparation and characterization of baru (Dipteryx alata Vog) nut protein isolate and comparison of its physico-chemical properties with commercial animal and plant protein isolates.

Science.gov (United States)

Nunes, Ângela A; Favaro, Simone P; Miranda, Cesar H B; Neves, Valdir A

2017-01-01

The Brazilian leguminous tree locally known in the Cerrado Biome as baru (Dipteryx alata Vog), provides a healthy edible oil source. The proteinaceous cake remaining after oil extraction could be transformed into new products to foodstuff development, such as protein concentrates and isolates, adding value to the production chain. In this study, it is described the preparation and characterization of baru nut protein isolate (BPI) from deffated baru flour, and measurements of its functional, nutritional, and thermal properties, in comparison to the more common vegetable (soybeans) and animal (casein and albumin) protein sources of the food industry. BPI presented higher protein content than soybean, casein and albumin commercial protein isolates, despite losses of albumins and low molecular weight globulins during the isolation procedure. Thermodynamics studies suggested that BPI has a well-conserved protein arrangement and lower thermostability than the other protein sources. BPI showed high in vitro digestibility and suitable and desirable functional properties such as water and oil absorption capacity, emulsifying activity, and foam formation and stability at mild and neutral pH. BPI could be used either as a substitute ingredient in oily food formulations or in the development of new products of its own. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.
Plasma heating by cluster injection: basic features and expected behaviour

International Nuclear Information System (INIS)

Bottiglioni, F.; Coutant, J.; Fois, M.; CEA Centre d'Etudes Nucleaires de Fontenay-aux-Roses, 92

1976-01-01

Each main component of an injection line (beam source, cluster ionizer, accelerating tube) is briefly discussed together with the behavior of clusters interacting with a plasma. Outlines of the experiment of cluster injection into TFR, in progress at Fontenay-aux-Roses are presented and discussed all along the paper. It is shown that high current densities at rather low energy per atom can be obtained by accelerated cluster beams. In present size toroidal devices, both ion temperature and density can be increased simultaneously without heating electrons. This feature could be attractive as long as tokamak losses are dominated by electrons. The extrapolation of the ionizers under construction does not seem to present much difficulty; on the contrary, the accelerating tube could be the most serious problem to solve. (40 references)

Zero-degree injection line for PILAC, the proposed Los Alamos Pion Linac

International Nuclear Information System (INIS)

Blind, B.

1991-01-01

In this paper, an optimized injection line for PILAC, the proposed Los Alamos Pion Linac, is presented. With the other optimized components (pion source, accelerator, and high-resolution beamline and spectrometer), the system is capable of delivering 10 9 920-MeV pions per second to the target. 3 refs., 2 figs
Field studies on two rock phosphate solubilizing actinomycete isolates as biofertilizer sources

Science.gov (United States)

Mba, Caroline C.

1994-03-01

Recently biotechnology is focusing attention on utilization of biological resources to solve a number of environmental problems such as soil fertility management. Results of microbial studies on earthworm compost in the University of Nigeria farm identified a number of rock phosphate solubilizing actinomycetes. Two of these, isclates 02 and 13, were found to be efficient rock phosphate (RP) solubilizers and fast-growing cellulolytic microbes producing extracellular hydrolase enzymes. In this preliminary field study the two microbial isolates were investigated with respect to their effects on the growth of soybean and egusi as well as their effect on the incidence of toxicity of poultry droppings. Application of these isolates in poultry manure-treated field plots, as microbial fertilizers, brought about yield increases of 43% and 17% with soybeans and 19% and 33% with egusi, respectively. Soil properties were also improved. With isolates 02 and 13, the soil available phosphorus increased at the five-leaf stage, while N-fixation in the soil increased by 45% or 11% relative to control. It was further observed that air-dried poultry manure after four days of incubation was still toxic to soybean. The toxic effect of the applied poultry manure was reduced or eliminated with microbial fertilizers 02 or 13, respectively. The beneficial effects of the microbial organic fertilizer are discussed. Justification for more intensive research on rock phosphate organic fertilizer is highlighted.
An investigation of methods for injecting emissions from boreal wildfires using WRF-Chem during ARCTAS

Directory of Open Access Journals (Sweden)

W. R. Sessions

2011-06-01

Full Text Available The Weather Research and Forecasting Model (WRF is considered a "next generation" mesoscale meteorology model. The inclusion of a chemistry module (WRF-Chem allows transport simulations of chemical and aerosol species such as those observed during NASA's Arctic Research of the Composition of the Troposphere from Aircraft and Satellites (ARCTAS in 2008. The ARCTAS summer deployment phase during June and July coincided with large boreal wildfires in Saskatchewan and Eastern Russia.

One of the most important aspects of simulating wildfire plume transport is the height at which emissions are injected. WRF-Chem contains an integrated one-dimensional plume rise model to determine the appropriate injection layer. The plume rise model accounts for thermal buoyancy associated with fires and local atmospheric stability. This paper describes a case study of a 10 day period during the Spring phase of ARCTAS. It compares results from the plume model against those of two more traditional injection methods: Injecting within the planetary boundary layer, and in a layer 3–5 km above ground level. Fire locations are satellite derived from the GOES Wildfire Automated Biomass Burning Algorithm (WF_ABBA and the MODIS thermal hotspot detection. Two methods for preprocessing these fire data are compared: The prep_chem_sources method included with WRF-Chem, and the Naval Research Laboratory's Fire Locating and Monitoring of Burning Emissions (FLAMBE. Results from the simulations are compared with satellite-derived products from the AIRS, MISR and CALIOP sensors.

When FLAMBE provides input to the 1-D plume rise model, the resulting injection heights exhibit the best agreement with satellite-observed injection heights. The FLAMBE-derived heights are more realistic than those utilizing prep_chem_sources. Conversely, when the planetary boundary layer or the 3–5 km a.g.l. layer were filled with emissions, the resulting injection heights exhibit less
ECR ion source for variable energy cyclotron

Energy Technology Data Exchange (ETDEWEB)

Bose, D K; Taki, G S; Nabhiraj, P Y; Pal, G; Dasgupta, B; Mallik, C; Das, S K; Bandopadhaya, D K; Bhandari, R K [Variable Energy Cyclotron Centre, Calcutta (India)

1995-09-01

Some performance characteristics of 6.4 GHz two stage ECR ion source which was under development at this centre is presented. The present ion source will facilitate acceleration of light heavy ions with the existing k=130 variable energy cyclotron. Multiply charged heavy ion (MCHI) beam from the source will also be utilized for atomic physics studies. Oxygen beam has already been used for ion implantation studies. The external injection system under development is nearing completion. Heavy ion beam from cyclotron is expected by end of 1995. (author).
QnrS1- and Aac(6’-Ib-cr-producing Escherichia coli among isolates from animals of different sources: susceptibility and genomic characterization

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Daniela eJones-Dias

2016-05-01

Full Text Available Salmonella enterica and Escherichia coli can inhabit humans and animals from multiple origins. These bacteria are often associated with gastroenteritis in animals, being a frequent cause of resistant zoonotic infections. In fact, bacteria from animals can be transmitted to humans through the food chain and direct contact. In this study, we aimed to assess the antibiotic susceptibility of a collection of S. enterica and E. coli recovered from animals of different sources, performing a genomic comparison of the plasmid-mediated quinolone resistance (PMQR-producing isolates detected.Antibiotic susceptibility testing revealed a high number of non wild-type isolates for fluoroquinolones among S. enterica recovered from poultry isolates. In turn, the frequency of non-wild-type E. coli to nalidixic acid and ciprofloxacin was higher in food-producing animals than in companion or zoo animals. Globally, we detected two qnrS1 and two aac(6’-Ib-cr in E. coli isolates recovered from animals of different origins. The genomic characterization of QnrS1-producing E. coli showed high genomic similarity (O86:H12 and ST2297, although they have been recovered from a healthy turtle dove from a Zoo Park, and from a dog showing symptoms of infection. The qnrS1 gene was encoded in a IncN plasmid, also carrying blaTEM-1-containing Tn3. Isolates harboring aac(6’-Ib-cr were detected in two captive bottlenose dolphins, within a time span of two years. The additional antibiotic resistance genes of the two aac(6’-Ib-cr-positive isolates (blaOXA-1, blaTEM-1, blaCTX-M-15, catB3, aac(3-IIa and tetA were enclosed in IncFIA plasmids that differed in a single transposase and 60 single nucleotide variants. The isolates could be assigned to the same genetic sublineage – ST131 fimH30-Rx (O25:H4, confirming clonal spread. PMQR-producing isolates were associated with symptomatic and asymptomatic hosts, which highlight the aptitude of E. coli to act as silent vehicles, allowing
In-Source Laser Resonance Ionization at ISOL Facilities

CERN Document Server

Marsh, Bruce; Feddosseev, Valentin

Resonance ionization laser ion source development has been carried out at two radioactive ion beam facilities: ISOLDE (CERN, Switzerland) and the IGISOL facility (Jyvaskyla, Finland). The scope of the Resonance Ionization Laser Ion Source has been extended to 27 elements with the development of new three-step ionization schemes for Sb, Sc, Dy, Y and Au. The efficiencies were determined to be in the range of 2 - 20 %. Additionally, a new two-step ionization scheme has been developed for bismuth in an off-line atomic beam unit. The scheme relies on ionization via a strong and broad auto-ionizing resonance at an energy of 63196.79 cm$^{−1}$. This scheme may offer an improvement over the existing RILIS efficiency and will be more convenient for use during resonance ionization spectroscopy of Bi isotopes. The RILIS can be used as a spectroscopic tool to probe features such as the hyperfine structures and the isotope-shifts of radioisotopes with low production rates. By coupling a laser scanning process that dire...
Irradiation of Liquid Fungi Isolated Media from Contaminated Sources with Heavy Metals Additive

International Nuclear Information System (INIS)

Tawfiq, E.; Mohamed, A.A.; El-Kabbany, H.M.

2012-01-01

Occupational lead exposure is an important health issue in Egyptian workers, employees of paint factories, workers of copying centres, drivers, and tile making factories are in higher risk of lead toxicity. Wastewater, particularly from electroplating, paint, leather, metal and tanning industries, contain enormous amount of heavy metals. Microorganisms including fungi have been reported to exclude heavy metals from wastewater through bioaccumulation and bio sorption at low cost and in eco-friendly way. Low level lead exposure can significantly induce motor dis functions and cognitive impairment in children. Seventy six fungal isolates tolerant to heavy metals like Pb, Cd, Cr and Ni were isolated from sewage, sludge and industrial effluents containing heavy metals. Four fungi (Phanerochaete chrysosporium, Aspergillus awamori, Aspergillus flavus, Trichoderma viride) were included in this study. The majority of the fungal isolates were able to tolerate up to 400 ppm concentration of Pb, Cd, Cr and Ni. The most heavy metal tolerant fungi were studied for removal of heavy metals from liquid media at 50 ppm concentration. Results indicated removal of substantial amount of heavy metals by some of the fungi with respect to Pb, Cd, Cr and Ni with maximum uptake of 59.67, 16.25, 0.55 and 0.55 mg/g by fungi Pb 3 (Aspergillus terreus), Trichoderma viride, C r 8 (Trichoderma longibrachiatum), and isolate Ni 27 (A. niger), respectively. This indicated the potential of these fungi as bio sorbent for removal of heavy metals from wastewater and industrial effluents containing higher concentration of heavy metals. The F-ratio was 0.55 and gives non-significant as irradiated
Marine Algae As A Prospective Source For Antidiabetic Compounds - A Brief Review.

Science.gov (United States)

Unnikrishnan, Pulikkaparambil Sasidharan; Jayasri, Mangalam Achuthananda

2018-01-01

Diabetes Mellitus (DM) is a metabolic disorder characterized by chronic hyperglycaemia, which is attributed to several life threatening complications including atherosclerosis, nephropathy, and retinopathy. The current therapies available for the management of DM mainly include oral antidiabetic drugs and insulin injections. However, continuous use of synthetic drugs provides lower healing with many side effects. Therefore, there is an urge for safe and efficient antidiabetic drugs for the management of DM. In the continuing search for effective antidiabetic drugs, marine algae (seaweeds) remains as a promising source with potent bioactivity. It is anticipated that the isolation, characterization, and pharmacological study of unexplored marine algae can be useful in the discovery of novel antidiabetic compounds with high biomedical value. Among marine algae, brown and red algae are reported to exhibit antidiabetic activity. Majority of the investigations on algal derived compounds controls the blood glucose levels through the inhbition of carbohydrate hydroloyzing enzymes and protein tyrosine phosphatase 1B enzymes, insulin sensitization, glucose uptake effect and other protective effects against diabetic complications. Based on the above perspective this review provides; profiles for various marine algae posessing antidiabetic activity. This study also highlights the therapeutic potential of compounds isolated from marine algae for the effective management of diabetes and its associated complications. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.
Repetitive laser fusion experiment and operation using a target injection system

International Nuclear Information System (INIS)

Nishimura, Yasuhiko; Komeda, Osamu; Mori, Yoshitaka

2017-01-01

Since 2008, a collaborative research project on laser fusion development based on a high-speed ignition method using repetitive laser has been carried out with several collaborative research institutes. This paper reports the current state of operation of high repetition laser fusion experiments, such as target introduction and control based on a target injection system that allows free falling under 1 Hz, using a high repetition laser driver that has been under research and development, as well as the measurement of targets that freely fall. The HAMA laser driver that enabled high repetition fusion experiments is a titanium sapphire laser using a diode-pumped solid-state laser KURE-I of green light output as a driver pump light source. In order to carry out high repetition laser fusion experiments, the target injection device allows free falling of deuterated polystyrene solid sphere targets of 1 mm in diameter under 1 Hz. The authors integrated the developed laser and injection system, and succeeded first in the world in making the nuclear fusion reaction continuously by hitting the target to be injected with laser, which is essential technology for future laser nuclear fusion reactor. In order to realize repetition laser fusion experiments, stable laser, target synchronization control, and target position measurement technologies are indispensable. (A.O.)
HIV-1 binding and neutralizing antibodies of injecting drug users

Directory of Open Access Journals (Sweden)

E.P. Ouverney

2005-09-01

Full Text Available Previous studies have demonstrated a stronger seroreactivity against some synthetic peptides responsible for inducing neutralizing antibodies in injecting drug users (IDU compared to that of individuals sexually infected with HIV-1 (S, but the effectiveness in terms of the neutralizing ability of these antibodies has not been evaluated. Our objective was to study the humoral immune response of IDU by determining the specificity of their antibodies and the presence of neutralizing antibodies. The neutralization capacity against the HIV-1 isolate MN (genotype B, the primary HIV-1 isolate 95BRRJ021 (genotype F, and the seroreactivity with peptides known to induce neutralizing antibodies, from the V2 and V3 loops of different HIV-1 subtypes, were analyzed. Seroreactivity indicates that IDU plasma are more likely to recognize a broader range of peptides than S plasma, with significantly higher titers, especially of V3 peptides. Similar neutralization frequencies of the MN isolate were observed in plasma of the IDU (16/47 and S (20/60 groups in the 1:10 dilution. The neutralization of the 95BRRJ021 isolate was more frequently observed for plasma from the S group (15/23 than from the IDU group (15/47, P = 0.0108. No correlation between neutralization and seroreactivity with the peptides tested was observed. These results suggest that an important factor responsible for the extensive and broad humoral immune response observed in IDU is their infection route. There was very little difference in neutralizing antibody response between the IDU and S groups despite their differences in seroreactivity and health status.
Characteristics of pressure wave in common rail fuel injection system of high-speed direct injection diesel engines

Directory of Open Access Journals (Sweden)

Mohammad Reza Herfatmanesh

2016-05-01

Full Text Available The latest generation of high-pressure common rail equipment now provides diesel engines possibility to apply as many as eight separate injection pulses within the engine cycle for reducing emissions and for smoothing combustion. With these complicated injection arrangements, optimizations of operating parameters for various driving conditions are considerably difficult, particularly when integrating fuel injection parameters with other operating parameters such as exhaust gas recirculation rate and boost pressure together for evaluating calibration results. Understanding the detailed effects of fuel injection parameters upon combustion characteristics and emission formation is therefore particularly critical. In this article, the results and discussion of experimental investigations on a high-speed direct injection light-duty diesel engine test bed are presented for evaluating and analyzing the effects of main adjustable parameters of the fuel injection system on all regulated emission gases and torque performance. Main injection timing, rail pressure, pilot amount, and particularly pilot timing have been examined. The results show that optimization of each of those adjustable parameters is beneficial for emission reduction and torque improvement under different operating conditions. By exploring the variation in the interval between the pilot injection and the main injection, it is found that the pressure wave in the common rail has a significant influence on the subsequent injection. This suggests that special attentions must be paid for adjusting pilot timing or any injection interval when multi-injection is used. With analyzing the fuel amount oscillation of the subsequent injections to pilot separation, it demonstrates that the frequency of regular oscillations of the actual fuel amount or the injection pulse width with the variation in pilot separation is always the same for a specified fuel injection system, regardless of engine speed
Locally Targeted Delivery of a Micron-Size Radiation Therapy Source Using Temperature-Sensitive Hydrogel

Energy Technology Data Exchange (ETDEWEB)

Kim, Yusung, E-mail: yusung-kim@uiowa.edu [Department of Radiation Oncology, The University of Iowa, Iowa City, Iowa (United States); Seol, Dong Rim [Department of Orthopaedic Surgery, The University of Iowa, Iowa City, Iowa (United States); Mohapatra, Sucheta [Department of Biomedical Engineering, The University of Iowa, Iowa City, Iowa (United States); Sunderland, John J. [Department of Radiology, The University of Iowa, Iowa City, Iowa (United States); Schultz, Michael K. [Department of Radiation Oncology, The University of Iowa, Iowa City, Iowa (United States); Department of Radiology, The University of Iowa, Iowa City, Iowa (United States); Domann, Frederick E. [Department of Radiation Oncology, The University of Iowa, Iowa City, Iowa (United States); Department of Surgery, The University of Iowa, Iowa City, Iowa (United States); Lim, Tae-Hong [Department of Biomedical Engineering, The University of Iowa, Iowa City, Iowa (United States)

2014-04-01

Purpose: To propose a novel radiation therapy (RT) delivery modality: locally targeted delivery of micron-size RT sources by using temperature-sensitive hydrogel (RT-GEL) as an injectable vehicle. Methods and Materials: Hydrogel is a water-like liquid at room temperature but gels at body temperature. Two US Food and Drug Administration-approved polymers were synthesized. Indium-111 (In-111) was used as the radioactive RT-GEL source. The release characteristics of In-111 from polymerized RT-GEL were evaluated. The injectability and efficacy of RT-GEL delivery to human breast tumor were tested using animal models with control datasets of RT-saline injection. As proof-of-concept studies, a total of 6 nude mice were tested by injecting 4 million tumor cells into their upper backs after a week of acclimatization. Three mice were injected with RT-GEL and 3 with RT-saline. Single-photon emission computed tomography (SPECT) and CT scans were performed on each mouse at 0, 24, and 48 h after injection. The efficacy of RT-GEL was determined by comparison with that of the control datasets by measuring kidney In-111 accumulation (mean nCi/cc), representing the distant diffusion of In-111. Results: RT-GEL was successfully injected into the tumor by using a 30-gauge needle. No difficulties due to polymerization of hydrogel during injection and intratumoral pressure were observed during RT-GEL injection. No back flow occurred for either RT-GEL or RT-saline. The residual tumor activities of In-111 were 49% at 24 h (44% at 48 h, respectively) for RT-GEL and 29% (22%, respectively) for RT-saline. Fused SPECT-CT images of RT-saline showed considerable kidney accumulation of In-111 (2886%, 261%, and 262% of RT-GEL at 0, 24, and 48 h, respectively). Conclusions: RT-GEL was successfully injected and showed much higher residual tumor activity: 170% (200%, respectively), than that of RT-saline at 24 h (48 h, respectively) after injection with a minimal accumulation of In-111 to the
Overcoming male factor infertility with intracytoplasmic sperm injection.

Science.gov (United States)

Borges, Edson; Zanetti, Bianca Ferrarini; Braga, Daniela Paes de Almeida Ferreira; Setti, Amanda Souza; Figueira, Rita de Cássia Sávio; Nardi, Aguinaldo César; Iaconelli, Assumpto

2017-08-01

To evaluate the effect of male factor infertility on intracytoplasmic sperm injection (ICSI) outcomes compared with a control group presenting isolated tubal factor. This retrospective study included 743 couples undergoing ICSI as a result of isolated male factor and a control group consisting of 179 couples undergoing ICSI as a result of isolated tubal factor, performed in a private university- -affiliated in vitro fertilization center, between January/2010 and December/2016. Patients were divided into two groups according to maternal age: women ≤35 years old and >35 years old. The effects of infertility causes on laboratorial and clinical ICSI outcomes were evaluated using Student's t-test and (2 test. No differences in controlled ovarian stimulation outcomes were observed between male factor cycles and tubal factor cycles in the two age groups. Implantation (male factor 35.5% vs. tubal factor 32.0%, p=0.340), pregnancy (male factor 46.9% vs. tubal factor 40.9%, p=0.184) and miscarriage (male factor 10.3% vs. tubal factor 10.6%, p=0.572) rates were similar between the infertility groups, irrespective of female age. Considering maternal age, the cancelation rate was higher in older women (>35 years old) undergoing ICSI as a result of male factor infertility (17.4% vs. 8.9%, p=0.013). Our results showed that there is no difference in the outcomes of pregnancy between couples with male or tubal factor infertility, which indicates that ICSI surpasses the worse specific outcomes associated with male factor.
Identification and Characterization of Oleaginous Yeast Isolated from Kefir and Its Ability to Accumulate Intracellular Fats in Deproteinated Potato Wastewater with Different Carbon Sources

Directory of Open Access Journals (Sweden)

Iwona Gientka

2017-01-01

Full Text Available The search for efficient oleaginous microorganisms, which can be an alternative to fossil fuels and biofuels obtained from oilseed crops, has been going on for many years. The suitability of microorganisms in this regard is determined by their ability to biosynthesize lipids with preferred fatty acid profile along with the concurrent utilization of energy-rich industrial waste. In this study, we isolated, characterized, and identified kefir yeast strains using molecular biology techniques. The yeast isolates identified were Candida inconspicua, Debaryomyces hansenii, Kluyveromyces marxianus, Kazachstania unispora, and Zygotorulaspora florentina. We showed that deproteinated potato wastewater, a starch processing industry waste, supplemented with various carbon sources, including lactose and glycerol, is a suitable medium for the growth of yeast, which allows an accumulation of over 20% of lipid substances in its cells. Fatty acid composition primarily depended on the yeast strain and the carbon source used, and, based on our results, most of the strains met the criteria required for the production of biodiesel. In particular, this concerns a significant share of saturated fatty acids, such as C16:0 and C18:0, and unsaturated fatty acids, such as C18:1 and C18:2. The highest efficiency in lipid biosynthesis exceeded 6.3 g L−1. Kazachstania unispora was able to accumulate the high amount of palmitoleic acid.
Identification and Characterization of Oleaginous Yeast Isolated from Kefir and Its Ability to Accumulate Intracellular Fats in Deproteinated Potato Wastewater with Different Carbon Sources.

Science.gov (United States)

Gientka, Iwona; Kieliszek, Marek; Jermacz, Karolina; Błażejak, Stanisław

2017-01-01

The search for efficient oleaginous microorganisms, which can be an alternative to fossil fuels and biofuels obtained from oilseed crops, has been going on for many years. The suitability of microorganisms in this regard is determined by their ability to biosynthesize lipids with preferred fatty acid profile along with the concurrent utilization of energy-rich industrial waste. In this study, we isolated, characterized, and identified kefir yeast strains using molecular biology techniques. The yeast isolates identified were Candida inconspicua , Debaryomyces hansenii , Kluyveromyces marxianus , Kazachstania unispora , and Zygotorulaspora florentina . We showed that deproteinated potato wastewater, a starch processing industry waste, supplemented with various carbon sources, including lactose and glycerol, is a suitable medium for the growth of yeast, which allows an accumulation of over 20% of lipid substances in its cells. Fatty acid composition primarily depended on the yeast strain and the carbon source used, and, based on our results, most of the strains met the criteria required for the production of biodiesel. In particular, this concerns a significant share of saturated fatty acids, such as C16:0 and C18:0, and unsaturated fatty acids, such as C18:1 and C18:2. The highest efficiency in lipid biosynthesis exceeded 6.3 g L -1 . Kazachstania unispora was able to accumulate the high amount of palmitoleic acid.
Identification and Characterization of Oleaginous Yeast Isolated from Kefir and Its Ability to Accumulate Intracellular Fats in Deproteinated Potato Wastewater with Different Carbon Sources

Science.gov (United States)

Kieliszek, Marek; Jermacz, Karolina; Błażejak, Stanisław

2017-01-01

The search for efficient oleaginous microorganisms, which can be an alternative to fossil fuels and biofuels obtained from oilseed crops, has been going on for many years. The suitability of microorganisms in this regard is determined by their ability to biosynthesize lipids with preferred fatty acid profile along with the concurrent utilization of energy-rich industrial waste. In this study, we isolated, characterized, and identified kefir yeast strains using molecular biology techniques. The yeast isolates identified were Candida inconspicua, Debaryomyces hansenii, Kluyveromyces marxianus, Kazachstania unispora, and Zygotorulaspora florentina. We showed that deproteinated potato wastewater, a starch processing industry waste, supplemented with various carbon sources, including lactose and glycerol, is a suitable medium for the growth of yeast, which allows an accumulation of over 20% of lipid substances in its cells. Fatty acid composition primarily depended on the yeast strain and the carbon source used, and, based on our results, most of the strains met the criteria required for the production of biodiesel. In particular, this concerns a significant share of saturated fatty acids, such as C16:0 and C18:0, and unsaturated fatty acids, such as C18:1 and C18:2. The highest efficiency in lipid biosynthesis exceeded 6.3 g L−1. Kazachstania unispora was able to accumulate the high amount of palmitoleic acid. PMID:29098157
Syringe-injectable electronics.

Science.gov (United States)

Liu, Jia; Fu, Tian-Ming; Cheng, Zengguang; Hong, Guosong; Zhou, Tao; Jin, Lihua; Duvvuri, Madhavi; Jiang, Zhe; Kruskal, Peter; Xie, Chong; Suo, Zhigang; Fang, Ying; Lieber, Charles M

2015-07-01

Seamless and minimally invasive three-dimensional interpenetration of electronics within artificial or natural structures could allow for continuous monitoring and manipulation of their properties. Flexible electronics provide a means for conforming electronics to non-planar surfaces, yet targeted delivery of flexible electronics to internal regions remains difficult. Here, we overcome this challenge by demonstrating the syringe injection (and subsequent unfolding) of sub-micrometre-thick, centimetre-scale macroporous mesh electronics through needles with a diameter as small as 100 μm. Our results show that electronic components can be injected into man-made and biological cavities, as well as dense gels and tissue, with >90% device yield. We demonstrate several applications of syringe-injectable electronics as a general approach for interpenetrating flexible electronics with three-dimensional structures, including (1) monitoring internal mechanical strains in polymer cavities, (2) tight integration and low chronic immunoreactivity with several distinct regions of the brain, and (3) in vivo multiplexed neural recording. Moreover, syringe injection enables the delivery of flexible electronics through a rigid shell, the delivery of large-volume flexible electronics that can fill internal cavities, and co-injection of electronics with other materials into host structures, opening up unique applications for flexible electronics.
Physics based simulation of seismicity induced in the vicinity of a high-pressure fluid injection

Science.gov (United States)

McCloskey, J.; NicBhloscaidh, M.; Murphy, S.; O'Brien, G. S.; Bean, C. J.

2013-12-01

High-pressure fluid injection into subsurface is known, in some cases, to induce earthquakes in the surrounding volume. The increasing importance of ';fracking' as a potential source of hydrocarbons has made the seismic hazard from this effect an important issue the adjudication of planning applications and it is likely that poor understanding of the process will be used as justification of refusal of planning in Ireland and the UK. Here we attempt to understand some of the physical controls on the size and frequency of induced earthquakes using a physics-based simulation of the process and examine resulting earthquake catalogues The driver for seismicity in our simulations is identical to that used in the paper by Murphy et al. in this session. Fluid injection is simulated using pore fluid movement throughout a permeable layer from a high-pressure point source using a lattice Boltzmann scheme. Diffusivities and frictional parameters can be defined independently at individual nodes/cells allowing us to reproduce 3-D geological structures. Active faults in the model follow a fractal size distribution and exhibit characteristic event size, resulting in a power-law frequency-size distribution. The fluid injection is not hydraulically connected to the fault (i.e. fluid does not come into physical contact with the fault); however stress perturbations from the injection drive the seismicity model. The duration and pressure-time function of the fluid injection can be adjusted to model any given injection scenario and the rate of induced seismicity is controlled by the local structures and ambient stress field as well as by the stress perturbations resulting from the fluid injection. Results from the rate and state fault models of Murphy et al. are incorporated to include the effect of fault strengthening in seismically quite areas. Initial results show similarities with observed induced seismic catalogues. Seismicity is only induced where the active faults have not been
The Isolation and Detection of Staphylococcus aureus Enterotoxins A-E and TSST-1 Genes from Different Sources by PCR Method

Directory of Open Access Journals (Sweden)

Norouzi J

2012-09-01

Full Text Available Background and Objectives: Enterotoxins and toxic shock syndrome toxin–1 (TSST-1 are an important virulence factor of S. aureus. The purpose of this study was to analyze the presence of S. aureus enterotoxin (sea-see and tst genes in the samples that collected from different sources with PCR method. Methods: During 5 months from 150 collected samples, 80 strains were identified as S. aureus. PCR reaction was used for investigation on the presence of genes for staphylococcal enterotoxins (A-E and toxic shock syndrome toxin-1 (TSST-1. Results: Fifty three samples (66.25% out of 80 samples were positive for one or more ETs and TSST-1 genes. of these positive strains, 17 (32.07% were positive for sea 39 (73.58% for seb, 30 (56.6% for sec, 2 (3.7% for sed, 21 (39.62% for see, and 14 (26.41% for tst. Enterotoxins and tst in 40 samples (75.47% observed.Conclusion: In this study, high prevalence of S. aureus, its enterotoxin, and tst genes were observed in clinical samples, food samples, and healthy people. This fact emphasizes on the role of human as original source and carrier of S. aureus. Also, use of PCR reaction for detection of these genes in S. aureus that isolated from various sources is recommended.
BANDWIDTH STUDIES OF AN INJECTION-SEEDED BETA-BARIUM BORATE OPTICAL PARAMETRIC OSCILLATOR

NARCIS (Netherlands)

Boonengering, J.M.; van der Veer, W.E.; Gerritsen, J.W.; Hogervorst, W.

1995-01-01

Spectral and temporal properties of a scanning injection-seeded β-barium borate optical parametric oscillator pumped by the third harmonic of a 10-Hz Nd:YAG laser have been studied. The seed source was a cw diode laser with a wavelength of 830 nm tunable over a range of 50 GHz. We measured the

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