WorldWideScience

Sample records for isa derivatives tend

  1. isa

    International Development Research Centre (IDRC) Digital Library (Canada)

    Rosario Quesada

    El proyecto “La exposición a plaguicidas y su relación con el neurodesarrollo de bebés de 0 a 2 años: un análisis integrado de la sostenibilidad de sistemas de producción de banano y plátano” denominado Infantes y Salud ambiental (ISA) parte de la necesidad de evaluar y mejorar la sostenibilidad de sistemas de ...

  2. Intelligent Speed Assistance (ISA).

    NARCIS (Netherlands)

    2015-01-01

    Intelligent Speed Assistance (ISA) has been a promising type of advanced driver support system for some decades. From a technical point of view, large scale ISA implementation is possible in the short term. The different types of ISA are expected to have different effects on behaviour and traffic

  3. IS-A diversified

    DEFF Research Database (Denmark)

    Nilsson, Jørgen Fischer

    2014-01-01

    We reconsider the nature and formal properties of the class inclusion relation, IS-A, from the point of view of information modeling and engineering of formal ontologies. In particular we review approaches to the elusive notion of intensionality. We then conduct an analysis adopting a metalogic s...

  4. Controlled study of ISA effects

    DEFF Research Database (Denmark)

    Harms, Lisbeth; Klarborg, Brith; Lahrmann, Harry

    2007-01-01

    The present study is a part of the ISA PAYD project being conducted in the County of North Jutland, Denmark. The first part of the study compared background data and attitudes between young ISA-volunteers and non-volunteers. Volunteers and nonvolunteers differed only with respect to their judgeme...

  5. Plant-derived differences in the composition of aphid honeydew and their effects on colonies of aphid-tending ants

    Science.gov (United States)

    Pringle, Elizabeth G; Novo, Alexandria; Ableson, Ian; Barbehenn, Raymond V; Vannette, Rachel L

    2014-01-01

    In plant–ant–hemipteran interactions, ants visit plants to consume the honeydew produced by phloem-feeding hemipterans. If genetically based differences in plant phloem chemistry change the chemical composition of hemipteran honeydew, then the plant's genetic constitution could have indirect effects on ants via the hemipterans. If such effects change ant behavior, they could feed back to affect the plant itself. We compared the chemical composition of honeydews produced by Aphis nerii aphid clones on two milkweed congeners, Asclepias curassavica and Asclepias incarnata, and we measured the responses of experimental Linepithema humile ant colonies to these honeydews. The compositions of secondary metabolites, sugars, and amino acids differed significantly in the honeydews from the two plant species. Ant colonies feeding on honeydew derived from A. incarnata recruited in higher numbers to artificial diet, maintained higher queen and worker dry weight, and sustained marginally more workers than ants feeding on honeydew derived from A. curassavica. Ants feeding on honeydew from A. incarnata were also more exploratory in behavioral assays than ants feeding from A. curassavica. Despite performing better when feeding on the A. incarnata honeydew, ant workers marginally preferred honeydew from A. curassavica to honeydew from A. incarnata when given a choice. Our results demonstrate that plant congeners can exert strong indirect effects on ant colonies by means of plant-species-specific differences in aphid honeydew chemistry. Moreover, these effects changed ant behavior and thus could feed back to affect plant performance in the field. PMID:25505534

  6. Assessing the origin of old apparent ages derived by Pb stepwise leaching of vein-hosted epidote from Mount Isa, northwest Queensland, Australia

    Science.gov (United States)

    Duncan, Robert J.; Maas, Roland

    2014-12-01

    Epidote metasomatism affected large areas of tholeiitic metabasalts of the ~1,780 Ma Eastern Creek Volcanics in the Western Fold Belt of the Proterozoic Mount Isa inlier. Hydrothermal epidote generally occurs in quartz veins parallel to or boudinaged within the dominant S2 fabrics which formed during the regional metamorphic peak at ~1,570 Ma associated with the Isan orogeny. Previously published stable isotopic and halogen data suggest that the fluids responsible for epidote formation are metamorphic in origin (with an evaporitic component). Application of the Pb stepwise leaching technique to the epidote does not separate radiogenic Pb4+ and common Pb2+, generating little spread in 206Pb/204Pb (between 16.0 and 30.5). The causes for this relatively low range are twofold: There is little radiogenic Pb in the epidotes (the most radiogenic steps account for leaching data give ages between 150 and 1,500 myrs older than the host rocks and over 450 myrs older than the thermal metamorphic peak. These old ages are attributed to chemical inheritance from the host metabasalts, via radiogenic Pb release by breakdown of phases such as zircon, monazite, titanomagnetite, and ilmenite during metamorphism. This idea is supported by trace element data and chrondrite-normalized rare earth element patterns that are similar to both the metabasalts and epidotes (except for a variable Eu anomaly in the latter). Relatively high fO2 during vein formation (Fe3+ dominates in the epidote crystal lattice) would allow the incorporation of Th4+ and exclusion of U6+ and would explain elevated Th/U ratios (up to 12) in epidote compared with the host metabasalts. Non-incorporation of U would explain the relatively low U/Pb ratios and non-radiogenic character of the epidote. This process may provide a source of metal for the small U deposits around Mount Isa and may also suggest a relationship between U mineralization and regional Cu mobilization during the Isan orogeny. Our work suggests that

  7. Onderzoeksopzet praktijkdemo intelligente snelheidsadaptatie ISA.

    NARCIS (Netherlands)

    Polak, P.H. & Roszbach, R.

    1999-01-01

    A practical experiment with intelligent speed adapters will be carried out in the Dutch borough of Tilburg during the period 1998-2000. The goal of this project is to: develop support and a public acceptance of ISA as a speed control instrument via a practical demonstration; and to gain insight in a

  8. A new Perspective on ISA-Equipment

    DEFF Research Database (Denmark)

    Klarborg, Brith; Lahrmann, Harry; Agerholm, Niels

    2007-01-01

    Intelligent Speed Adaptation [ISA] has proved successful at reducing the speed of normal drivers. However, until now the potential of ISA as an assistive device has been neglected. Two case studies were conducted to test ISA as a support for drivers with acquired brain injury [ABI] in driving wit...

  9. The Iran Sanctions Act (ISA)

    Science.gov (United States)

    2009-06-04

    billion4 contract (September 1997) for Total SA of France and its partners, Gazprom of Russia and Petronas of Malaysia to develop phases 2 and 3 of the 25...companies. On July 12, 2008, Total and Petronas , the original South Pars investors, pulled out of a deal to develop a liquified natural gas (LNG...do not exceed the $20 million in one year threshold for ISA sanctionability. Since the Total/ Petronas /Gazprom project in 1998, no projects have

  10. Vacuum guidelines for ISA insertions

    International Nuclear Information System (INIS)

    Edwards, D. Jr.

    1976-01-01

    Vacuum requirements place design restrictions on the ISA insertions. The vacuum tube diameter, given a distance L between pumps, is determined by the desorption of molecules from the wall under the impact of ions created by the beam, whereas the thickness of the tube must be sufficient to prevent collapse. In addition, the entire vacuum chamber must be able to be baked out at approximately 200 0 C

  11. LABORATORY DIAGNOSIS OF INFECTIOUS SALMON ANEMIA (ISA)

    DEFF Research Database (Denmark)

    Schyth, Brian Dall; Olesen, Niels Jørgen; Østergaard, Peter

    The first outbreak of ISA on the Faroe Islands was diagnosed in March 2000. Despite intensive surveillance, control and eradication of ISA, the disease has since spread to most of the Faroe Islands affecting about half of the 23 aquaculture farms. Sampling and laboratory diagnosis of ISA is perfo......The first outbreak of ISA on the Faroe Islands was diagnosed in March 2000. Despite intensive surveillance, control and eradication of ISA, the disease has since spread to most of the Faroe Islands affecting about half of the 23 aquaculture farms. Sampling and laboratory diagnosis of ISA...... is performed according to the EU Commission Decision draft on sampling and diagnostic procedures for ISA. Inspection, clinical and gross-pathological examination and tissue sampling is performed by the veterinarians on the islands. Laboratory examination is done in collaboration between the Veterinary...

  12. Integrated Science Assessment (ISA) for Sulfur Oxides ...

    Science.gov (United States)

    This draft document provides EPA’s evaluation and synthesis of the most policy-relevant science related to the health effects of sulfur oxides. When final, it will provide a critical part of the scientific foundation for EPA’s decision regarding the adequacy of the current primary (health-based) National Ambient Air Quality Standard (NAAQS) for sulfur dioxide. The references considered for inclusion in or cited in the external review draft ISA are available at https://hero.epa.gov/hero/sulfur-oxides. The intent of the ISA, according to the CAA, is to “accurately reflect the latest scientific knowledge expected from the presence of [a] pollutant in ambient air” (U.S. Code, 1970a, 1970b). It includes an assessment of scientific research from atmospheric sciences, exposure sciences, dosimetry, mode of action, animal and human toxicology, and epidemiology. Key information and judgments formerly found in the Air Quality Criteria Documents (AQCDs) for sulfur oxides (SOx) are included; Annexes provide additional details supporting the ISA. Together, the ISA and Annexes serve to update and revise the last SOx ISA which was published in 2008.

  13. mzML2ISA & nmrML2ISA: generating enriched ISA-Tab metadata files from metabolomics XML data.

    Science.gov (United States)

    Larralde, Martin; Lawson, Thomas N; Weber, Ralf J M; Moreno, Pablo; Haug, Kenneth; Rocca-Serra, Philippe; Viant, Mark R; Steinbeck, Christoph; Salek, Reza M

    2017-08-15

    Submission to the MetaboLights repository for metabolomics data currently places the burden of reporting instrument and acquisition parameters in ISA-Tab format on users, who have to do it manually, a process that is time consuming and prone to user input error. Since the large majority of these parameters are embedded in instrument raw data files, an opportunity exists to capture this metadata more accurately. Here we report a set of Python packages that can automatically generate ISA-Tab metadata file stubs from raw XML metabolomics data files. The parsing packages are separated into mzML2ISA (encompassing mzML and imzML formats) and nmrML2ISA (nmrML format only). Overall, the use of mzML2ISA & nmrML2ISA reduces the time needed to capture metadata substantially (capturing 90% of metadata on assay and sample levels), is much less prone to user input errors, improves compliance with minimum information reporting guidelines and facilitates more finely grained data exploration and querying of datasets. mzML2ISA & nmrML2ISA are available under version 3 of the GNU General Public Licence at https://github.com/ISA-tools. Documentation is available from http://2isa.readthedocs.io/en/latest/. reza.salek@ebi.ac.uk or isatools@googlegroups.com. Supplementary data are available at Bioinformatics online. © The Author(s) 2017. Published by Oxford University Press.

  14. Pay as You Speed, ISA with incentive for not speeding

    DEFF Research Database (Denmark)

    Lahrmann, Harry Spaabæk; Agerholm, Niels; Tradisauskas, Nerius

    2012-01-01

    To simulate a market introduction of Intelligent Speed Adaptation (ISA) and to study the effect of a Pay as You Speed (PAYS) concept, a field trial with 153 drivers was conducted during 2007–2009. The participants drove under PAYS conditions for a shorter or a longer period. The PAYS concept......, with and without incentive crossed with informative ISA present or absent. The results showed that ISA is an efficient tool for reducing speeding particularly on rural roads. The analysis of speed data demonstrated that the proportion of distance driven above the speed where the ISA equipment responded (PDA...... level. Both informative ISA and incentive ISA reduced the PDA, but there was no statistically significant interaction. Informative reduced it more than the incentive....

  15. Intelligente snelheidsadaptatie ISA : een vergelijking van Nederlandse en Zweedse systemen.

    NARCIS (Netherlands)

    Oei, H.-l.

    1998-01-01

    An important part within developments in the field of telematics is Intelligent Speed Adaptation (ISA). Especially in Sweden, where the policy objective is to have zero fatalities or seriously injured victims on the road in 2020, research has been conducted on ISA during the last 10 years. In the

  16. Isa-ema maa : [luuletused] / Leelo Tungal

    Index Scriptorium Estoniae

    Tungal, Leelo, 1947-

    2001-01-01

    Sisu: Isa-ema maa ; Vahetund ; Päkapikk võis näha ; Kodune jutt ; Koeruse mõõt ; mütsid ; Loomade laul ; Igal sügisel ; Väike jõulusoov ; Millal tuled, jõuluvana ; Paharet ; Suur õun ; Teiste laste mänguasjad ; Oi heldeke! ; Tere-tere ; Kui ma ... ; Magus tähestik ; Pluss ja miinus ; Pinalis ; Esimese klassi õpilane ; Teise klassi õpilane ; Miks on kana vana? ; Hommik ; Seitsme maa ja mere taga ; Köha pere ; Harjad ; Täna sügist mängib suvi ; Toas ; Laps jäi voodis magama ; Klassivennad ; Talvehommik ; Siili elu ; Hiirehernesupp ; Hundi lugemine ; Karu ärkamine ; Unelaul ; Salajutt ; Kooli eel ; Laiskvorsti elu ; Kindel plaan ; Oma kohal ; Puhkama ; Vana vahva lasteaed ; Sama laps ; Tüli

  17. Reading the New Standard ISA700

    Directory of Open Access Journals (Sweden)

    Daniel Botez

    2010-12-01

    Full Text Available Review of permanent professional standards is a requirement for professional bodies of professional accountants, resulting in broader processes of globalization and harmonization. A set of revised standards on financial audit engagement was published by IFAC in April 2009. International Standard on Auditing (ISA 700 "Forming an opinion and reporting on financial statements” is one of them. This standard deals with the auditor's responsibility to form an opinion on the financial statements and determine the form and content of the auditor's report issued following an audit of financial statements. Even if you do not have major changes, the revised standard contains several provisions that emphasize the important role of the auditor's report and more specifically defines its responsibility.

  18. Pay as You Speed, ISA with incentives for not speeding

    DEFF Research Database (Denmark)

    Lahrmann, Harry Spaabæk; Agerholm, Niels; Tradisauskas, Nerius

    2012-01-01

    The Intelligent Speed Adaptation (ISA) project we describe in this article is based on Pay as You Drive principles. These principles assume that the ISA equipment informs a driver of the speed limit, warns the driver when speeding and calculates penalty points. Each penalty point entails the redu......The Intelligent Speed Adaptation (ISA) project we describe in this article is based on Pay as You Drive principles. These principles assume that the ISA equipment informs a driver of the speed limit, warns the driver when speeding and calculates penalty points. Each penalty point entails...... the reduction of a 30% discount on the driver's car insurance premium, which therefore produced the name, Pay as You Speed. The ISA equipment consists of a GPS-based On Board Unit with a mobile phone connection to a web server. The project was planned for a three-year test period with 300 young car drivers...

  19. Presidendi poeg piinab isa poliitilisi vastaseid / Aadu Hiietamm

    Index Scriptorium Estoniae

    Hiietamm, Aadu, 1954-

    2004-01-01

    Pärast Moskva-meelse Ahmad Kadõrovi valimist Tšetšeenia presidendiks valitseb olukord, kus presidendi poeg Ramzan peab vanglat ja tapab isa poliitilisi vastaseid, väidetakse maailma ajakirjanduses

  20. ISA 247: trans-ISA 247, trans-R 1524, ISA(TX)247, ISAtx 247, ISATx247, LX 211, LX211, R 1524, R-1524.

    Science.gov (United States)

    2007-01-01

    Isotechnika is developing the immunosuppressive drug ISA 247, a calcineurin inhibitor that is undergoing clinical development for the treatment of psoriasis (phase III) and prevention of organ rejection after transplantation (phase II). Preclinical development for uveitis is also underway. Other autoimmune disease indications that could be explored include arthritis, type I diabetes and Crohn's disease. ISA 247 was being co-developed as R 1524 by Isotechnika and Roche. However, Roche is no longer involved in the development of this compound. Based on analysis of previously collected data, the trans-ISA 247 isomer was found to be more bioavailable and it is expected that this isomer can be administered at a lower dose compared with the previous formulation that consisted of an equivalent mixture of the two geometric isomers (cis and trans). Preclinical observations indicate that ISA 247 has the potential to be more potent and less toxic than other marketed immunosuppressants in its class used for the prevention of transplant rejection. Experiments to date suggest that ISA 247 is about three times as potent as ciclosporin, while genotoxicity studies in animals have shown that the compound has a significantly reduced tendency to cause renal toxicity. The combination of reduced toxicity and improved potency would give ISA 247 a therapeutic benefit over existing calcineurin-based treatments. Isotechnika and Roche entered into a co-development and commercialisation agreement in April 2002, with Roche gaining the exclusive worldwide marketing rights for ISA 247; Isotechnika received milestone payments of $US4 million and $CAN21.9 million in September 2002 and May 2003, respectively. The agreement was restructured in April 2004, under which Isotechnika will now solely manage and fund the clinical development of trans-ISA 247. Upon successful completion of these trials, Isotechnika will conduct at its own expense a phase IIb study in renal transplantation and phase III

  1. Integrated Science Assessment (ISA) for Oxides of Nitrogen ...

    Science.gov (United States)

    This draft ISA document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision on retaining or revising the current secondary standards for NO2, SO2, PM 2.5 and PM 10 since the prior release of the assessment. The intent of the ISA, according to the CAA, is to “accurately reflect the latest scientific knowledge expected from the presence of [a] pollutant in ambient air” (U.S. Code, 1970a, 1970b). It includes scientific research from atmospheric sciences, exposure and deposition, biogeochemistry, hydrology, soil science, marine science, plant physiology, animal physiology, and ecology conducted at multiple scales (e.g., population, community, ecosystem, landscape levels). Key information and judgments formerly found in the Air Quality Criteria Documents (AQCDs) for oxides of nitrogen, oxides of nitrogen and particulate matter for ecological effects are included; Appendixes provide additional details supporting the ISA. Together, the ISA and Appendixes serve to update and revise the last oxides of nitrogen and oxides of sulfur ISA which was published in 2008 and the ecological portion of the last particulate matter ISA, which was published in 2009.

  2. Thermodynamic model of Ni(II) solubility, hydrolysis and complex formation with ISA

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez-Siso, Maria Rosa; Duro, Lara; Bruno, Jordi [Amphos21, Barcelona (Spain); Gaona, Xavier; Altmaier, Marcus [Karlsruhe Institute of Technology (KIT), Karlsruhe (Germany). Inst. for Nuclear Waste Disposal

    2018-04-01

    the low solubility (<10{sup -7} M) of Ni(II) in hyperalkaline pH conditions representative of cementitious environments (10 ≤ pH ≤ 13), which increases to up to 10{sup -5} M in the presence of 0.2 M NaISA. These results significantly improve source term estimations for Ni(II) in environments relevant for the disposal of low and intermediate level radioactive waste (L/ILW). The chemical and thermodynamic models derived in this work can be implemented in geochemical models/calculations, and provide further confidence in the safety analysis of repositories for the disposal of L/ILW.

  3. Development of ISA procedure for uranium fuel fabrication and enrichment facilities: overview of ISA procedure and its application

    International Nuclear Information System (INIS)

    Yamate, Kazuki; Yamada, Takashi; Takanashi, Mitsuhiro; Sasaki, Noriaki

    2013-01-01

    Integrated Safety Analysis (ISA) procedure for uranium fuel fabrication and enrichment facilities has been developed for aiming at applying risk-informed regulation to these uranium facilities. The development has carried out referring to the ISA (NUREG-1520) by the Nuclear Regulatory Commission (NRC). The paper presents purpose, principles and activities for the development of the ISA procedure, including Risk Level (RL) matrix and grading evaluation method of IROFS (Items Relied on for Safety), as well as general description and features of the procedure. Also described in the paper is current status in application of risk information from the ISA. Japanese four licensees of the uranium facilities have been conducting ISA for their representative processes using the developed procedure as their voluntary safety activities. They have been accumulating experiences and knowledge on the ISA procedure and risk information through the field activities. NISA (Nuclear and Industrial Safety Agency) and JNES (Japan Nuclear Energy Safety Organization) are studying how to use such risk information for the safety regulation of the uranium facilities, taking into account the licensees' experiences and knowledge. (authors)

  4. Electron clearing for the ISA proton beam

    International Nuclear Information System (INIS)

    Herrera, J.C.

    1976-01-01

    The circulating protons in the ISABELLE intersecting storage ring accelerator will collide with the residual gas in the vacuum chamber. The electrons produced will tend to be captured by the potential well of the beam itself and result in a neutralization of the space charge of the beam. A detailed analysis is given of the various mechanisms which can be used to reduce the net degree of beam neutralization. It is concluded that the average neutralization will be about 10 -4 for a residual gas pressure of 3 x 10 -11 torr of hydrogen

  5. Vahetuspere isa osutus seksuaalseks ahistajaks / Merje Pors ; kommenteerinud Oliver Kontram

    Index Scriptorium Estoniae

    Pors, Merje

    2011-01-01

    Vahetusõpilase ahistamise juhtumist Argentiinas, kus vahetuspere isa kuritarvitas seksuaalselt vahetusõpilast. Vahetusprogrammide kaudu välismaale õppima minejate arvu vähenemisest, mistõttu on programmid sunnitud ümber orienteeruma ja rohkem välisõpilasi Eestisse tooma

  6. Evaluation of Montanide™ ISA 71 VG adjuvant during profilin vaccination against experimental coccidiosis.

    Directory of Open Access Journals (Sweden)

    Seung I Jang

    Full Text Available Chickens were immunized subcutaneously with an Eimeria recombinant profilin protein plus Montanide™ ISA 70 VG (ISA 70 or Montanide™ ISA 71 VG (ISA 71 water-in-oil adjuvants, or with profilin alone, and comparative RNA microarray hybridizations were performed to ascertain global transcriptome changes induced by profilin/ISA 70 vs. profilin alone and by profilin/ISA 71 vs. profilin alone. While immunization with profilin/ISA 70 vs. profilin alone altered the levels of more total transcripts compared with profilin/ISA 71 vs. profilin alone (509 vs. 296, the latter was associated with a greater number of unique biological functions, and a larger number of genes within these functions, compared with the former. Further, canonical pathway analysis identified 10 pathways that were associated with genes encoding the altered transcripts in animals immunized with profilin/ISA 71 vs. profilin alone, compared with only 2 pathways in profilin/ISA 70 vs. profilin alone. Therefore, ISA 71 was selected as a candidate adjuvant in conjunction with profilin vaccination for in vivo disease protection studies. Vaccination with profilin/ISA 71 was associated with greater body weight gain following E. acervulina infection, and decreased parasite fecal shedding after E. maxima infection, compared with profilin alone. Anti-profilin antibody levels were higher in sera of E. maxima- and E. tenella-infected chickens vaccinated with profilin/ISA 71 compared with profilin alone. Finally, the levels of transcripts encoding interferon-γ, interleukin (IL-2, IL-10, and IL-17A were increased in intestinal lymphocytes from E. acervulina-, E. maxima-, and/or E. tenella-infected chickens vaccinated with profilin/ISA 71 compared with profilin alone. None of these effects were seen in chickens injected with ISA 71 alone indicating that the adjuvant was not conferring non-specific immune stimulation. These results suggest that profilin plus ISA 71 augments protective immunity

  7. Evaluation of Montanide™ ISA 71 VG Adjuvant during Profilin Vaccination against Experimental Coccidiosis

    Science.gov (United States)

    Lillehoj, Hyun S.; Lee, Sung Hyen; Lee, Kyung Woo; Bertrand, François; Dupuis, Laurent; Deville, Sébastien; Ben Arous, Juliette; Lillehoj, Erik P.

    2013-01-01

    Chickens were immunized subcutaneously with an Eimeria recombinant profilin protein plus Montanide™ ISA 70 VG (ISA 70) or Montanide™ ISA 71 VG (ISA 71) water-in-oil adjuvants, or with profilin alone, and comparative RNA microarray hybridizations were performed to ascertain global transcriptome changes induced by profilin/ISA 70 vs. profilin alone and by profilin/ISA 71 vs. profilin alone. While immunization with profilin/ISA 70 vs. profilin alone altered the levels of more total transcripts compared with profilin/ISA 71 vs. profilin alone (509 vs. 296), the latter was associated with a greater number of unique biological functions, and a larger number of genes within these functions, compared with the former. Further, canonical pathway analysis identified 10 pathways that were associated with genes encoding the altered transcripts in animals immunized with profilin/ISA 71 vs. profilin alone, compared with only 2 pathways in profilin/ISA 70 vs. profilin alone. Therefore, ISA 71 was selected as a candidate adjuvant in conjunction with profilin vaccination for in vivo disease protection studies. Vaccination with profilin/ISA 71 was associated with greater body weight gain following E. acervulina infection, and decreased parasite fecal shedding after E. maxima infection, compared with profilin alone. Anti-profilin antibody levels were higher in sera of E. maxima- and E. tenella-infected chickens vaccinated with profilin/ISA 71 compared with profilin alone. Finally, the levels of transcripts encoding interferon-γ, interleukin (IL)-2, IL-10, and IL-17A were increased in intestinal lymphocytes from E. acervulina-, E. maxima-, and/or E. tenella-infected chickens vaccinated with profilin/ISA 71 compared with profilin alone. None of these effects were seen in chickens injected with ISA 71 alone indicating that the adjuvant was not conferring non-specific immune stimulation. These results suggest that profilin plus ISA 71 augments protective immunity against selective

  8. WACANA NARATIF KEHIDUPAN NABI ISA DALAM AL-QURʼAN

    Directory of Open Access Journals (Sweden)

    Toto Edidarmo

    2014-06-01

    Full Text Available The Holy Quran contains the faith, worship, Islamic morals, history, promises and threats, and information about Hereafter (eschatology. The narrative style of the Quran is less systematic and intact except the narration of the Prophet Yusuf (Surah Yusuf [12]: 1-111. This paper narrates the verses of the Quran about Prophet Isa's life since his birth, prophetness, until death. The aim is to reconstruct narrative discourse of Prophet Isa's life as a systematical text. The method used is content analysis through verses related analysis in order to classify the meaning and connect the verses with other verses into a systematize form, a unified narrative and chronological discourse. DOI: 10.15408/a.v1i1.1133

  9. ISA-97 Compliant Architecture Testbed (ICAT) Projectry Organizations

    Science.gov (United States)

    1992-03-30

    by the System Integracion Directorate of the USAISEC, August 29, 1992. The report discusses the refinement of the ISA-97 Compliant Architecture Model...browser and iconic representations of system objects and resources. When the user is interacting with an application which has multiple compo- nents, it is...computer communications, it is not uncommon for large information systems to be shared by users on multiple machines. The trend towards the desktop

  10. Electron clearing and dimensional tolerance for the ISA chamber

    International Nuclear Information System (INIS)

    Herrera, J.C.

    1976-01-01

    In the straight sections of the ISA ring, the clearing of the low energy electrons produced by the beam-gas collisions will take place by longitudinal motion. Thus, an electron of low energy, which is prevented from escaping transversely by the attractive field of the beam, will receive successive kicks by the circulating protons and thereby acquire sufficient energy to travel longitudinally toward the clearing electrodes. However, a discontinuity or step in the chamber diameter, which occurs within an axial distance equal to a few diameters, gives rise to a potential difference along the chamber axis. In the case of a section of chambers which has a larger diameter, that is, a small cavity, the two steps result in a longitudinal potential well, or attractive region. It is then necessary that the electrons be given additional energy in order to overcome this longitudinal trapping potential. The ISA design envisions the placement of clearing electrodes at the location of significant chamber discontinuities, particularly in the experimental insertions. An estimate of the magnitude of the diameter discontinuity that can be tolerated without a clearing electrode is given

  11. Is it reliable that speed-calming solutions as ISA can reach the drivers, who needed it most?

    DEFF Research Database (Denmark)

    Agerholm, Niels

    A significant number of trials with Intelligent Speed Adaptation (ISA) have been carried out within the last two decades. Almost all with a promising result; the drivers reduce their proportion of speeding and are in general positive to ISA. However, two tings question this offhand success story; 1......: there has been no commercial break through for ISA so far, even though estimated has shown that ISA can reduce the n. of fatalities in traffic accidents with up to 59%, and 2: in the only ISA trial included drivers, who not participated voluntary in the trial, ISA had virtually no effect on these drivers...

  12. Integrated Science Assessment (ISA) for Carbon Monoxide (Second External Review Draft, Sep 2009)

    Science.gov (United States)

    EPA announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Carbon Monoxide (CO) and related Annexes was made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluation of t...

  13. Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria (First External Review Draft, Sep 2007)

    Science.gov (United States)

    EPA has announced that the First External Review Draft of the Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria has been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluatio...

  14. Politiek draagvlak voor Intelligente Snelheidsaanpassing (ISA) : interviewstudie onder vertegenwoordigers van Nederlandse politieke partijen.

    NARCIS (Netherlands)

    Goldenbeld, C.

    2004-01-01

    Many road safety experts regard Intelligent Speed Adaptation (ISA) as a powerful instrument for regulating safe driving speeds and achieving more safety. In short, ISA ensures that, while it is in motion, the vehicle `receives' information about the speed limit that applies where it is. When driving

  15. Electron clearing and dimensional tolerance for the ISA chamber

    International Nuclear Information System (INIS)

    Herrera, J.C.

    1976-01-01

    In the straight sections of the ISA ring, the clearing of the low energy electrons produced by the beam-gas collisions will take place by longitudinal motion. Thus, an electron of low energy, which is prevented from escaping transversely by the attractive field of the beam, will receive successive kicks by the circulating protons and thereby acquire sufficient energy to travel longitudinally toward the clearing electrodes. However, a discontinuity or step in the chamber diameter, which occurs within an axial distance equal to a few diameters, gives rise to a potential difference along the chamber axis. An estimate of the magnitude of the diameter discontinuity that can be tolerated without a clearing electrode is given

  16. Grave Tending: With Mom at the Cemetery

    Directory of Open Access Journals (Sweden)

    Carolyn Ellis

    2003-05-01

    Full Text Available This autoethnographic story shows the process of tending the graves of family members. In the past, the author reluctantly accompanied her mother on her visits to the family cemetery. Once there, she took on the role of distant observer as her mother took care of the family cemetery plots. When her mother becomes disabled, the author begins to arrange the flowers on the graves. Doing so leads her to examine the meaning of visiting the cemetery, feel and connect with her losses, and consider the customs she wants to be part of her own death. When her mother dies, the next generation of women in the family—the author, her sister, and sister-in-law—take on the role of tending the graves, connected in their love and respect for their mother and their feelings of family and family responsibility. This story examines the meanings of family rituals around death and how they are passed from generation to generation. URN: urn:nbn:de:0114-fqs0302285

  17. The biogeochemical fate of nickel during microbial ISA degradation; implications for nuclear waste disposal.

    Science.gov (United States)

    Kuippers, Gina; Boothman, Christopher; Bagshaw, Heath; Ward, Michael; Beard, Rebecca; Bryan, Nicholas; Lloyd, Jonathan R

    2018-06-08

    Intermediate level radioactive waste (ILW) generally contains a heterogeneous range of organic and inorganic materials, of which some are encapsulated in cement. Of particular concern are cellulosic waste items, which will chemically degrade under the conditions predicted during waste disposal, forming significant quantities of isosaccharinic acid (ISA), a strongly chelating ligand. ISA therefore has the potential to increase the mobility of a wide range of radionuclides via complex formation, including Ni-63 and Ni-59. Although ISA is known to be metabolized by anaerobic microorganisms, the biodegradation of metal-ISA complexes remains unexplored. This study investigates the fate of a Ni-ISA complex in Fe(III)-reducing enrichment cultures at neutral pH, representative of a microbial community in the subsurface. After initial sorption of Ni onto Fe(III)oxyhydroxides, microbial ISA biodegradation resulted in >90% removal of the remaining Ni from solution when present at 0.1 mM, whereas higher concentrations of Ni proved toxic. The microbial consortium associated with ISA degradation was dominated by close relatives to Clostridia and Geobacter species. Nickel was preferentially immobilized with trace amounts of biogenic amorphous iron sulfides. This study highlights the potential for microbial activity to help remove chelating agents and radionuclides from the groundwater in the subsurface geosphere surrounding a geodisposal facility.

  18. Bibliotecas escolares: tendências globais

    Directory of Open Access Journals (Sweden)

    Kelley Cristine Gonçalves Dias Gasque

    2016-09-01

    Full Text Available Este artigo aborda as transformações do processo de ensinoaprendizagem e das tecnologias e o impacto dessas nas bibliotecas escolares, especificamente, na formação do acervo, na configuração do espaço e no papel dos bibliotecários. A análise da literatura mostra tendência à adoção de modelos de aprendizagem baseados na construção colaborativa do conhecimento, com ênfase na aprendizagem compreensiva e atividades de ensino em ambientes diversificados. As bibliotecas escolares podem acolher e subsidiar atividades de ensino variadas, transformando-se em locais não apenas de apropriação da informação, mas também de produção do conhecimento por meio de atividades colaborativas, conectadas e diversificadas. O bibliotecário precisa fortalecer o domínio de tecnologias para obtenção, gerenciamento, produção e compartilhamento de informações. O fomento à leitura continua a ser importante, mas precisa ser ampliado para diferentes suportes e formatos.

  19. Sharing data for production scheduling using the ISA-95 standard

    Directory of Open Access Journals (Sweden)

    Iiro eHarjunkoski

    2014-10-01

    Full Text Available In the development and deployment of production scheduling solutions one major challenge is to establish efficient information sharing with industrial production management systems. Information comprising production orders to be scheduled, processing plant structure, product recipes, available equipment and other resources are necessary for producing a realistic short-term production plan. Currently, a widely-accepted standard for information sharing is missing. This often leads to the implementation of costly custom-tailored interfaces, or in the worst case the scheduling solution will be abandoned. Additionally, it becomes difficult to easily compare different methods on various problem instances, which complicates the re-use of existing scheduling solutions. In order to overcome these hurdles, a platform-independent and holistic approach is needed. Nevertheless, it is difficult for any new solution to gain wide acceptance within industry as new standards are often refused by companies already using a different established interface. From an acceptance point of view, the ISA-95 standard could act as a neutral data-exchange platform. In this paper, we assess if this already widespread standard is simple, yet powerful enough to act as the desired holistic data-exchange for scheduling solutions.

  20. Sharing Data for Production Scheduling Using the ISA-95 Standard

    Energy Technology Data Exchange (ETDEWEB)

    Harjunkoski, Iiro, E-mail: iiro.harjunkoski@de.abb.com; Bauer, Reinhard [ABB Corporate Research, Industrial Software and Applications, Ladenburg (Germany)

    2014-10-21

    In the development and deployment of production scheduling solutions, one major challenge is to establish efficient information sharing with industrial production management systems. Information comprising production orders to be scheduled, processing plant structure, product recipes, available equipment, and other resources are necessary for producing a realistic short-term production plan. Currently, a widely accepted standard for information sharing is missing. This often leads to the implementation of costly custom-tailored interfaces, or in the worst case the scheduling solution will be abandoned. Additionally, it becomes difficult to easily compare different methods on various problem instances, which complicates the re-use of existing scheduling solutions. In order to overcome these hurdles, a platform-independent and holistic approach is needed. Nevertheless, it is difficult for any new solution to gain wide acceptance within industry as new standards are often refused by companies already using a different established interface. From an acceptance point of view, the ISA-95 standard could act as a neutral data-exchange platform. In this paper, we assess if this already widespread standard is simple, yet powerful enough to act as the desired holistic data exchange for scheduling solutions.

  1. Sharing Data for Production Scheduling Using the ISA-95 Standard

    International Nuclear Information System (INIS)

    Harjunkoski, Iiro; Bauer, Reinhard

    2014-01-01

    In the development and deployment of production scheduling solutions, one major challenge is to establish efficient information sharing with industrial production management systems. Information comprising production orders to be scheduled, processing plant structure, product recipes, available equipment, and other resources are necessary for producing a realistic short-term production plan. Currently, a widely accepted standard for information sharing is missing. This often leads to the implementation of costly custom-tailored interfaces, or in the worst case the scheduling solution will be abandoned. Additionally, it becomes difficult to easily compare different methods on various problem instances, which complicates the re-use of existing scheduling solutions. In order to overcome these hurdles, a platform-independent and holistic approach is needed. Nevertheless, it is difficult for any new solution to gain wide acceptance within industry as new standards are often refused by companies already using a different established interface. From an acceptance point of view, the ISA-95 standard could act as a neutral data-exchange platform. In this paper, we assess if this already widespread standard is simple, yet powerful enough to act as the desired holistic data exchange for scheduling solutions.

  2. Evelin Ilvese isa : oleme tütrega ära leppinud / Karoliina Vasli

    Index Scriptorium Estoniae

    Vasli, Karoliina

    2007-01-01

    Proua Evelin Ilvese Helsingis elav isa Lembit Int räägib oma suhetest tütre ja väimehega. Vt. samas: Isa: "Evelinil on kahju, et unistus külalistemajast hetkel soiku jääb." Lembit Int väljendab kahetsust, et Ärma talu enam külalistemajana ei tööta

  3. ISA100.11a*: The ISA100.11a extension for supporting energy-harvested I/O devices

    NARCIS (Netherlands)

    Zand, P.; Mathews, E.; Das, Kallol; Dilo, Arta; Havinga, Paul J.M.

    Wireless standards developed for industrial applications such as ISA100.11a and WirelessHART, generally use centralized management approaches. However, such centralized approaches cannot cope with network dynamicity in real-time manner. They also incur high management overhead and latency.

  4. Current status and applications of intergrated safety assessment and simulation code system for ISA

    Energy Technology Data Exchange (ETDEWEB)

    Izquierdo, J. M.; Hortal, J.; Perea, M. Sanchez; Melendez, E. [Modeling and Simulation Area (MOSI), Nuclear Safety Council (CSN), Madrid (Spain); Queral, E.; Rivas-Lewicky, J. [Energy and Fuels Department, Technical University of Madrid (UPM), Madrid (Spain)

    2017-03-15

    This paper reviews current status of the unified approach known as integrated safety assessment (ISA), as well as the associated SCAIS (simulation codes system for ISA) computer platform. These constitute a proposal, which is the result of collaborative action among the Nuclear Safety Council (CSN), University of Madrid (UPM), and NFQ Solutions S.L, aiming to allow independent regulatory verification of industry quantitative risk assessments. The content elaborates on discussions of the classical treatment of time in conventional probabilistic safety assessment (PSA) sequences and states important conclusions that can be used to avoid systematic and unacceptable underestimation of the failure exceedance frequencies. The unified ISA method meets this challenge by coupling deterministic and probabilistic mutual influences. The feasibility of the approach is illustrated with some examples of its application to a real size plant.

  5. ISA-TAB-Nano: A Specification for Sharing Nanomaterial Research Data in Spreadsheet-based Format

    Science.gov (United States)

    2013-01-01

    Background and motivation The high-throughput genomics communities have been successfully using standardized spreadsheet-based formats to capture and share data within labs and among public repositories. The nanomedicine community has yet to adopt similar standards to share the diverse and multi-dimensional types of data (including metadata) pertaining to the description and characterization of nanomaterials. Owing to the lack of standardization in representing and sharing nanomaterial data, most of the data currently shared via publications and data resources are incomplete, poorly-integrated, and not suitable for meaningful interpretation and re-use of the data. Specifically, in its current state, data cannot be effectively utilized for the development of predictive models that will inform the rational design of nanomaterials. Results We have developed a specification called ISA-TAB-Nano, which comprises four spreadsheet-based file formats for representing and integrating various types of nanomaterial data. Three file formats (Investigation, Study, and Assay files) have been adapted from the established ISA-TAB specification; while the Material file format was developed de novo to more readily describe the complexity of nanomaterials and associated small molecules. In this paper, we have discussed the main features of each file format and how to use them for sharing nanomaterial descriptions and assay metadata. Conclusion The ISA-TAB-Nano file formats provide a general and flexible framework to record and integrate nanomaterial descriptions, assay data (metadata and endpoint measurements) and protocol information. Like ISA-TAB, ISA-TAB-Nano supports the use of ontology terms to promote standardized descriptions and to facilitate search and integration of the data. The ISA-TAB-Nano specification has been submitted as an ASTM work item to obtain community feedback and to provide a nanotechnology data-sharing standard for public development and adoption. PMID

  6. Application of the integrated analysis of safety (ISA) to sequences of Total loss of feed water in a PWR Reactor

    International Nuclear Information System (INIS)

    Moreno Chamorro, P.; Gallego Diaz, C.

    2011-01-01

    The main objective of this work is to show the current status of the implementation of integrated analysis of safety (ISA) methodology and its SCAIS associated tool (system of simulation codes for ISA) to the sequence analysis of total loss of feedwater in a PWR reactor model Westinghouse of three loops with large, dry containment.

  7. Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria (Final Report, Sep 2008)

    Science.gov (United States)

    EPA announced the availability of the final report, Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria final assessment. This report represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scien...

  8. 75 FR 69078 - Workshop To Review Draft Materials for the Lead (Pb) Integrated Science Assessment (ISA)

    Science.gov (United States)

    2010-11-10

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9224-7] Workshop To Review Draft Materials for the Lead (Pb) Integrated Science Assessment (ISA) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of Workshop... (NAAQS) for Lead (Pb), EPA is announcing that a workshop to evaluate initial draft materials for the Pb...

  9. Year 2000 compliance concerns with the ISA Thermoluminescent Dosimetry Data Processing (TL-DP) software system

    Energy Technology Data Exchange (ETDEWEB)

    Saviz, K.

    1998-05-26

    The year 2000 is rapidly approaching, and there is a good chance that computer systems that utilize two digit year dates will experience problems in retrieval of date information. The ISA Thermoluminescent Dosimetry Data Processing (TL-DP) software and computer system has been reviewed for Year 2000 compliance issues.

  10. Year 2000 compliance concerns with the ISA Thermoluminescent Dosimetry Data Processing (TL-DP) software system

    International Nuclear Information System (INIS)

    Saviz, K.

    1998-01-01

    The year 2000 is rapidly approaching, and there is a good chance that computer systems that utilize two digit year dates will experience problems in retrieval of date information. The ISA Thermoluminescent Dosimetry Data Processing (TL-DP) software and computer system has been reviewed for Year 2000 compliance issues

  11. Denaturing gradient gel electrophoresis (DGGE as a powerful novel alternative for differentiation of epizootic ISA virus variants.

    Directory of Open Access Journals (Sweden)

    Marisela Carmona

    Full Text Available Infectious Salmon Anemia is a devastating disease critically affecting world-wide salmon production. Chile has been particularly stricken by this disease which in all cases has been directly related with its causative agent, a novel orthomyxovirus which presents specific and distinctive infective features. Among these, two molecular markers have been directly associated with pathogenicity in two of the eight RNA sub genomic coding units of the virus: an insertion hot spot region present in viral segment 5 and a Highly Polymorphic Region (HPR located in viral segment 6. Here we report the successful adaptation of a PCR-dependent denaturing gel electrophoresis technique (DGGE, which enables differentiation of selected reported HPR epizootic variants detected in Chile. At the same time, the technique allows us to distinguish one nucleotide differences in sequences associated with the intriguing, and still not well-understood, insertion events which tend to occur on RNA Segment 5. Thus, the versatility of the technique opens new opportunities for improved understanding of the complex biology of all ISA variants as well as possible applications to other highly variable pathogens.

  12. Mining and urban impacts on semi-arid freshwater aquatic systems: the example of Mount Isa, Queensland.

    Science.gov (United States)

    Taylor, Mark P; Mackay, Alana; Kuypers, Tabitha; Hudson-Edwards, Karen

    2009-05-01

    This paper examines the environmental risk and impact of trace metals affecting river water and sediment in and around Mount Isa, Queensland, Australia. Bacterial indicator densities are also analysed throughout the catchment to assess the impacts and the potential hazards arising from agricultural activities, sewage treatment plant releases and urban runoff. The area is drained by the ephemeral Leichhardt River, which bisects Mount Isa City and the major Pb, Zn, Cu and Ag Mount Isa Mine. Runoff is captured downstream in Lake Moondarra, with the water being used following natural filtration via a lagoon-reed bed system for potable purposes by the residents of Mount Isa City. During the dry season, the channel is characterised by numerous pools that act as storage zones for sediment and water-soluble metals as well as urban and agriculturally derived nutrients and pathogens. Our results show that sediment and water quality within the Leichhardt River adjacent to and downstream of the mine frequently exceed Australian government sediment guidelines with average values of Cu, Pb and Zn found adjacent to the footprint of the mine being 1550, 510 and 470 mg kg(-1), respectively. Dry season analysis of water-soluble Cu, Pb and Zn concentrations within pools showed that Australian government low trigger guidelines are exceeded in 100, 46 and 100% cases, respectively. The densities of bacterial indicators in remnant pools throughout the Leichhardt River also exceeded acceptable guidelines. Maximum dry season faecal coliform densities of 2000 colony forming units (CFU) per 100 mL and Enterococcus counts of 900 organisms per 100 mL were recorded in dry season remnant pools compared to wet season maximum faecal coliform and Enterococcus densities of 119 000 CFU per 100 mL and 95 000 organisms per 100 mL, respectively. The impacts on biota were also examined by assessing the metal content of the tissue of seven fish from Lake Moondarra for their Cd, Cu, Hg, Pb and Zn

  13. Ant tending influences soldier production in a social aphid.

    Science.gov (United States)

    Shingleton, A W; Foster, W A

    2000-09-22

    The aphid Pseudoregma sundanica (Van der Goot) (Homoptera: Aphididae) has two defence strategies. It is obligatorily tended by various species of ant and also produces sterile soldiers. We investigated how they allocate their investment in these two strategies. We measured the size, number of soldiers, number and species of tending ant, and number and species of predators in P. sundanica populations. We found that the level of ant tending correlated negatively with soldier investment in P. sundanica. The species of tending ant also influenced soldier investment. We excluded ants from aphid populations and recorded changes in population size and structure over four weeks. Ant exclusion led to population decline and extinction. At the same time, surviving populations showed a significant increase in soldier investment. The data demonstrate that social aphids can adjust their investment in soldiers in direct response to environmental change.

  14. Graphemes Sharing Phonetic Features Tend to Induce Similar Synesthetic Colors

    OpenAIRE

    Kang, Mi-Jeong; Kim, Yeseul; Shin, Ji-Young; Kim, Chai-Youn

    2017-01-01

    Individuals with grapheme-color synesthesia experience idiosyncratic colors when viewing achromatic letters or digits. Despite large individual differences in grapheme-color association, synesthetes tend to associate graphemes sharing a perceptual feature with similar synesthetic colors. Sound has been suggested as one such feature. In the present study, we investigated whether graphemes of which representative phonemes have similar phonetic features tend to be associated with analogous synes...

  15. Development of ISA procedure for uranium fuel fabrication and enrichment facilities

    International Nuclear Information System (INIS)

    Yamate, Kazuki; Arakawa, Tomoyuki; Yamashita, Masahiro; Sasaki, Noriaki; Hirano, Mitsumasa

    2011-01-01

    The integrated safety analysis (ISA) procedure has been developed to apply risk-informed regulation to uranium fuel fabrication and enrichment facilities. The major development efforts are as follows: (a) preparing the risk level matrix as an index for items-relied-on-for-safety (IROFS) identification, (b) defining requirements of IROFS, and (c) determining methods of IROFS importance based on the results of risk- and scenario-based analyses. For the risk level matrix, the consequence and likelihood categories have been defined by taking into account the Japanese regulatory laws, rules, and safety standards. The trial analyses using the developed procedure have been performed for several representative processes of the reference uranium fuel fabrication and enrichment facilities. This paper presents the results of the ISA for the sintering process of the reference fabrication facility. The results of the trial analyses have demonstrated the applicability of the procedure to the risk-informed regulation of these facilities. (author)

  16. Open architecture design and approach for the Integrated Sensor Architecture (ISA)

    Science.gov (United States)

    Moulton, Christine L.; Krzywicki, Alan T.; Hepp, Jared J.; Harrell, John; Kogut, Michael

    2015-05-01

    Integrated Sensor Architecture (ISA) is designed in response to stovepiped integration approaches. The design, based on the principles of Service Oriented Architectures (SOA) and Open Architectures, addresses the problem of integration, and is not designed for specific sensors or systems. The use of SOA and Open Architecture approaches has led to a flexible, extensible architecture. Using these approaches, and supported with common data formats, open protocol specifications, and Department of Defense Architecture Framework (DoDAF) system architecture documents, an integration-focused architecture has been developed. ISA can help move the Department of Defense (DoD) from costly stovepipe solutions to a more cost-effective plug-and-play design to support interoperability.

  17. Integrated Safety Assessment (ISA): An approach for the assessment of the software aspects of protection systems

    International Nuclear Information System (INIS)

    Izquierdo-Rocha, Jose Maria; Sanchez-Perea, Miguel; Cojazzi, Giacomo

    2004-01-01

    This paper reviews the main features of ISA, a concept developed as a result of previous work on safety assessment and dynamic reliability. The method links the dynamics of the facility with its operating environment, subject to transitions between different time evolutions due to failures and/or system/operator interventions. For situations dominated by Deterministic Transitions (i.e., transitions upon deterministic demands as a result for instance of exceeding automatic-actions/alarm setpoints), the methodology can be considered an extension of PSA and accident analysis techniques that replaces the static event tree with a Deterministic Dynamic Event Tree (DDET) concept based on the Theory of Probabilistic Dynamics. The paper also summarizes some results of an ISA application to the assessment of the Emergency Operating Procedure (EOP) of a PWR-W to mitigate the Steam Generator Tube Rupture (SGTR) initiating event. (author)

  18. "Isa kuhu need värvid jäävad ..." : [luuletused] / Jaan Kaplinski

    Index Scriptorium Estoniae

    Kaplinski, Jaan, 1941-

    2002-01-01

    Sisu: "Isa kuhu need värvid jäävad ..." ; Lume ootamine ; "Oh sina paha peavalu ..." ; "Märg on vihmal märg on kastel ..." ; "Peet kisub peeti ..." ; "Küllap väikestel mustadel ..." ; "Mart haigutab ..." ; Kuu ; Teremees Tõnu ; Jalgrataste talveuni ; Kitsu ja kätsu ; Siret siret siterkuuti ; Suve soe silmadesse ; Iirimaal on ilmalapsed ; Miks ; Sügisel ; Täis ; Mis algab ; Aeg ; "Ma koiduajal ärkasin ..."

  19. Development of an international standard on instruments setpoints based on ISA S67.04 - 1994

    International Nuclear Information System (INIS)

    Quinn, E.L.

    1996-01-01

    This is a summary of the application for and development of an international standard on instrument setpoints, based on the Instrument Society of America (ISA) Standard S67.04 - 1994. The forum this new standard was proposed in is the International Electrotechnique Commission (IEC), based in Geneva, Switzerland, which is the international commission which oversees electrical and instrumentation standards for all applications around the world. The Instrument Society of America (ISA) is a United States based Society for the advancement of instrumentation and controls related science and technology and has 30,000 members. A division within the ISA is the Standard and Practices board which has over 5000 members actively involved in standards development and approval. In 1994, the ISA SP67, Nuclear Power Plant Standards Committee authorized that the IEC be approached to develop and issue an IEC standard on Instrument Setpoints. This application was formally submitted in January, 1995 to the IEC and approved for ballot to member countries in June, 1995. Approval for standard development by IEC was received in October, 1995 and the first draft vas issued in February, 1996, and is currently under review by the IEC working group. It is very important to focus on the approach that the U.S. and other countries are taking toward development of IEC standards that can apply to all nuclear instrumentation applications around the world. By referencing IEC standards in design specification, vendors can be solicited from many different countries, thereby ensuring that the highest quality products can be used. This also offsets the need to specify individual standards in the specification, based on the country that each vendor solicited, represents. In summary, this standard development process, with support from the American National Standards Institute (ANSI) will assist U.S. suppliers in competing in the global market for products and services into the next century. (author)

  20. Tend to Compare and Tend to Be Fair: The Relationship between Social Comparison Sensitivity and Justice Sensitivity

    OpenAIRE

    Zhen, Shanshan; Yu, Rongjun

    2016-01-01

    Social comparison is a prerequisite for processing fairness, although the two types of cognition may be associated with different emotions. Whereas social comparison may induce envy, the perception of unfairness may elicit anger. Yet, it remains unclear whether people who tend to have a strong sense of fairness also tend to compare themselves more with others. Here, Study 1 used a modified ultimatum game (UG) and a social comparison game (SCG) to examine the relationship between justice sensi...

  1. Hayabusa Asteroidal Sample Preliminary Examination Team (HASPET) and the Astromaterial Curation Facility at JAXA/ISAS

    Science.gov (United States)

    Yano, H.; Fujiwara, A.

    After the successful launch in May 2003, the Hayabusa (MUSES-C) mission of JAXA/ISAS will collect surface materials (e.g., regolith) of several hundred mg to several g in total from the S-type near Earth asteroid (25143) Itokawa in late 2005 and bring them back to ground laboratories in the summer of 2007. The retrieved samples will be given initial analysis at the JAXA/ISAS astromaterial curation facility, which is currently in the preparation for its construction, by the Hayabusa Asteroidal Sample Preliminary Examination Team (HASPET). HASPET is consisted of the ISAS Hayabusa team, the international partners from NASA and Australia and all-Japan meteoritic scientists to be selected as outsourcing parts of the initial analyses. The initial analysis to characterize general aspects of returned samples can consume only 15 % of its total mass and must complete the whole analyses including the database building before international AO for detailed analyses within the maximum of 1 year. Confident exercise of non-destructive, micro-analyses whenever possible are thus vital for the HASPET analysis. In the purpose to survey what kinds and levels of micro-analysis techniques in respective fields, from major elements and mineralogy to trace and isotopic elements and organics, are available in Japan at present, ISAS has conducted the HASPET open competitions in 2000-01 and 2004. The initial evaluation was made by multiple domestic peer reviews. Applicants were then provided two kinds of unknown asteroid sample analogs in order to conduct proposed analysis with self-claimed amount of samples in self-claimed duration. After the completion of multiple, international peer reviews, the Selection Committee compiled evaluations and recommended the finalists of each round. The final members of the HASPET will be appointed about 2 years prior to the Earth return. Then they will conduct a test-run of the whole initial analysis procedures at the ISAS astromaterial curation facility and

  2. How We Tend To Overestimate Powerlaw Tail Exponents

    OpenAIRE

    Nassim N. Taleb

    2012-01-01

    In the presence of a layer of metaprobabilities (from uncertainty concerning the parameters), the asymptotic tail exponent corresponds to the lowest possible tail exponent regardless of its probability. The problem explains "Black Swan" effects, i.e., why measurements tend to chronically underestimate tail contributions, rather than merely deliver imprecise but unbiased estimates.

  3. Monothiol glutaredoxin Grx5 interacts with Fe-S scaffold proteins Isa1 and Isa2 and supports Fe-S assembly and DNA integrity in mitochondria of fission yeast

    International Nuclear Information System (INIS)

    Kim, Kyoung-Dong; Chung, Woo-Hyun; Kim, Hyo-Jin; Lee, Kyung-Chang; Roe, Jung-Hye

    2010-01-01

    Mitochondrial monothiol glutaredoxins that bind Fe-S cluster are known to participate in Fe-S cluster assembly. However, their precise role has not been well understood. Among three monothiol glutaredoxins (Grx3, 4, and 5) in Schizosaccharomyces pombe only Grx5 resides in mitochondria. The Δgrx5 mutant requires cysteine on minimal media, and does not grow on non-fermentable carbon source such as glycerol. We found that the mutant is low in the activity of Fe-S enzymes in mitochondria as well as in the cytoplasm. Screening of multi-copy suppressor of growth defects of the mutant identified isa1 + gene encoding a putative A-type Fe-S scaffold, in addition to mas5 + and hsc1 + genes encoding putative chaperones for Fe-S assembly process. Examination of other scaffold and chaperone genes revealed that isa2 + , but not isu1 + and ssc1 + , complemented the growth phenotype of Δgrx5 mutant as isa1 + did, partly through restoration of Fe-S enzyme activities. The mutant also showed a significant decrease in the amount of mitochondrial DNA. We demonstrated that Grx5 interacts in vivo with Isa1 and Isa2 proteins in mitochondria by observing bimolecular fluorescence complementation. These results indicate that Grx5 plays a central role in Fe-S assembly process through interaction with A-type Fe-S scaffold proteins Isa1 and Isa2, each of which is an essential protein in S. pombe, and supports mitochondrial genome integrity as well as Fe-S assembly.

  4. Phase 1 trial of malaria transmission blocking vaccine candidates Pfs25 and Pvs25 formulated with montanide ISA 51.

    Directory of Open Access Journals (Sweden)

    Yimin Wu

    2008-07-01

    Full Text Available Pfs25 and Pvs25, surface proteins of mosquito stage of the malaria parasites P. falciparum and P. vivax, respectively, are leading candidates for vaccines preventing malaria transmission by mosquitoes. This single blinded, dose escalating, controlled Phase 1 study assessed the safety and immunogenicity of recombinant Pfs25 and Pvs25 formulated with Montanide ISA 51, a water-in-oil emulsion.The trial was conducted at The Johns Hopkins Center for Immunization Research, Washington DC, USA, between May 16, 2005-April 30, 2007. The trial was designed to enroll 72 healthy male and non-pregnant female volunteers into 1 group to receive adjuvant control and 6 groups to receive escalating doses of the vaccines. Due to unexpected reactogenicity, the vaccination was halted and only 36 volunteers were enrolled into 4 groups: 3 groups of 10 volunteers each were immunized with 5 microg of Pfs25/ISA 51, 5 microg of Pvs25/ISA 51, or 20 microg of Pvs25/ISA 51, respectively. A fourth group of 6 volunteers received adjuvant control (PBS/ISA 51. Frequent local reactogenicity was observed. Systemic adverse events included two cases of erythema nodosum considered to be probably related to the combination of the antigen and the adjuvant. Significant antibody responses were detected in volunteers who completed the lowest scheduled doses of Pfs25/ISA 51. Serum anti-Pfs25 levels correlated with transmission blocking activity.It is feasible to induce transmission blocking immunity in humans using the Pfs25/ISA 51 vaccine, but these vaccines are unexpectedly reactogenic for further development. This is the first report that the formulation is associated with systemic adverse events including erythema nodosum.ClinicalTrials.gov NCT00295581.

  5. Graphemes Sharing Phonetic Features Tend to Induce Similar Synesthetic Colors.

    Science.gov (United States)

    Kang, Mi-Jeong; Kim, Yeseul; Shin, Ji-Young; Kim, Chai-Youn

    2017-01-01

    Individuals with grapheme-color synesthesia experience idiosyncratic colors when viewing achromatic letters or digits. Despite large individual differences in grapheme-color association, synesthetes tend to associate graphemes sharing a perceptual feature with similar synesthetic colors. Sound has been suggested as one such feature. In the present study, we investigated whether graphemes of which representative phonemes have similar phonetic features tend to be associated with analogous synesthetic colors. We tested five Korean multilingual synesthetes on a color-matching task using graphemes from Korean, English, and Japanese orthography. We then compared the similarity of synesthetic colors induced by those characters sharing a phonetic feature. Results showed that graphemes associated with the same phonetic feature tend to induce synesthetic color in both within- and cross-script analyses. Moreover, this tendency was consistent for graphemes that are not transliterable into each other as well as graphemes that are. These results suggest that it is the perceptual-i.e., phonetic-properties associated with graphemes, not just conceptual associations such as transliteration, that determine synesthetic color.

  6. Graphemes Sharing Phonetic Features Tend to Induce Similar Synesthetic Colors

    Science.gov (United States)

    Kang, Mi-Jeong; Kim, Yeseul; Shin, Ji-Young; Kim, Chai-Youn

    2017-01-01

    Individuals with grapheme-color synesthesia experience idiosyncratic colors when viewing achromatic letters or digits. Despite large individual differences in grapheme-color association, synesthetes tend to associate graphemes sharing a perceptual feature with similar synesthetic colors. Sound has been suggested as one such feature. In the present study, we investigated whether graphemes of which representative phonemes have similar phonetic features tend to be associated with analogous synesthetic colors. We tested five Korean multilingual synesthetes on a color-matching task using graphemes from Korean, English, and Japanese orthography. We then compared the similarity of synesthetic colors induced by those characters sharing a phonetic feature. Results showed that graphemes associated with the same phonetic feature tend to induce synesthetic color in both within- and cross-script analyses. Moreover, this tendency was consistent for graphemes that are not transliterable into each other as well as graphemes that are. These results suggest that it is the perceptual—i.e., phonetic—properties associated with graphemes, not just conceptual associations such as transliteration, that determine synesthetic color. PMID:28348537

  7. The in-depth safety assessment (ISA) pilot projects in Ukraine

    International Nuclear Information System (INIS)

    Kot, C. A.

    1998-01-01

    Ukraine operates pressurized water reactors of the Soviet-designed type, VVER. All Ukrainian plants are currently operating with annually renewable permits until they update their safety analysis reports (SARs). After approval of the SARS by the Ukrainian Nuclear Regulatory Authority, the plants will be granted longer-term operating licenses. In September 1995, the Nuclear Regulatory Authority and the Government Nuclear Power Coordinating Committee of Ukraine issued a new contents requirement for the safety analysis reports of VVERs in Ukraine. It contains requirements in three major areas: design basis accident (DBA) analysis, probabilistic risk assessment (PRA), and beyond design-basis accident (BDBA) analysis. The DBA requirements are an expanded version of the older SAR requirements. The last two requirements, on PRA and BDBA, are new. The US Department of Energy (USDOE), through the International Nuclear Safety Program (INSP), has initiated an assistance and technology transfer program to Ukraine to assist their nuclear power stations in developing a Western-type technical basis for the new SARS. USDOE sponsored In-Depth Safety Assessments (ISAs) have been initiated at three pilot nuclear reactor units in Ukraine, South Ukraine Unit 1, Zaporizhzhya Unit 5, and Rivne Unit 1. USDOE/INSP have structured the ISA program in such a way as to provide maximum assistance and technology transfer to Ukraine while encouraging and supporting the Ukrainian plants to take the responsibility and initiative and to perform the required assessments

  8. Kepler Planets Tend to Have Siblings of the Same Size

    Science.gov (United States)

    Kohler, Susanna

    2017-11-01

    After 8.5 years of observations with the Kepler space observatory, weve discovered a large number of close-in, tightly-spaced, multiple-planet systems orbiting distant stars. In the process, weve learned a lot about the properties about these systems and discovered some unexpected behavior. A new study explores one of the properties that has surprised us: planets of the same size tend to live together.Orbital architectures for 25 of the authors multiplanet systems. The dots are sized according to the planets relative radii and colored according to mass. Planets of similar sizes and masses tend to live together in the same system. [Millholland et al. 2017]Ordering of SystemsFrom Keplers observations of extrasolar multiplanet systems, we have seen that the sizes of planets in a given system arent completely random. Systems that contain a large planet, for example, are more likely to contain additional large planets rather than additional planets of random size. So though there is a large spread in the radii weve observed for transiting exoplanets, the spread within any given multiplanet system tends to be much smaller.This odd behavior has led us to ask whether this clustering occurs not just for radius, but also for mass. Since the multiplanet systems discovered by Kepler most often contain super-Earths and mini-Neptunes, which have an extremely large spread in densities, the fact that two such planets have similar radii does not guarantee that they have similar masses.If planets dont cluster in mass within a system, this would raise the question of why planets coordinate only their radii within a given system. If they do cluster in mass, it implies that planets within the same system tend to have similar densities, potentially allowing us to predict the sizes and masses of planets we might find in a given system.Insight into MassesLed by NSF graduate research fellow Sarah Millholland, a team of scientists at Yale University used recently determined masses for

  9. Tendências de pesquisas brasileiras sobre mulheres mastectomizadas

    OpenAIRE

    Azevedo, Elisângela Braga de; Bezerra, Pollyana Amorim Ponce de Leon; Neto, José Melquiades Ramalho; Bustorff, Leila Alcina Correia Vaz; Souto, Cláudia Maria Ramos Medeiros

    2012-01-01

    Objetivou-se analisar as tendências das pesquisas realizadas no Brasil sobre mulheres mastectomizadas. Trata-se de um estudo bibliográfico de abordagem quantitativa, realizado de 15 de junho a 31 de julho de 2009. Para coleta dos dados empíricos utilizou-se um instrumento estruturado, posteriormente os dados foram tabulados, analisados, transformados em porcentagens e agrupados em uma tabela para facilitar a visualização das informações. A amostra foi constituída por resumos adquiridos atravé...

  10. O modelo ISA/JP - indicador de performance para diagnóstico do saneamento ambiental urbano ISA/JP model - indicator of performance for the diagnosis of urban environmental health

    Directory of Open Access Journals (Sweden)

    Marie Eugénie Malzac Batista

    2006-03-01

    Full Text Available Neste artigo apresenta-se o modelo ISA/JP - Indicador de Salubridade Ambiental, para análise intra-urbana por setor censitário e bairro como uma contribuição para a gestão urbana com enfoque para a área de saneamento ambiental. Trata-se de uma adaptação do ISA desenvolvido pelo Conselho Estadual de Saneamento do Estado de São Paulo, em 1999. Foi incorporado ao modelo ISA mais um sub-indicador, o de drenagem urbana. A utilização do modelo ISA/JP em um Sistema de Informação Geográfica - SIG permitiu que fosse explorada a potencialidade da espacialização dos resultados. Possibilitou ainda a representação e modelagem do conhecimento, constituindo um Sistema de Apoio a Decisão Espacial - SADE. É apresentado um estudo de caso nos bairros costeiros da cidade de João Pessoa, Brasil. Foi demonstrada a viabilidade do modelo proposto bem como o avanço na descrição da salubridade ambiental, mostrando a variabilidade das informações relevantes no espaço urbano.This work deals with the ISA/JP model - Indicator of Environmental Health for intra-urban analysis, according to the census sector and suburb, as a contribution to the urban management, with a focus on the area of environmental sanitation. It is an adaptation of ISA developed by São Paulo's State Council of Sanitation, in 1999. One more sub-indicator, that of urban drainage, was incorporated to the ISA model. The use of ISA/JP in a System of Geographic Information - SIG - permitted the exploration of the potentiality of distributing the results in the urban area. It also made possible the representation and modeling of knowledge, thus making up a System of Support to Space Decision - SSSD. A case study in the coastal suburbs of João Pessoa City, Brazil, was presented. The viability of the proposed model as well as the advance in the description of environmental health were demonstrated, thus showing the variability of relevant information in the urban space.

  11. Elevated atmospheric carbon dioxide concentrations promote ant tending of aphids.

    Science.gov (United States)

    Kremer, Jenni M M; Nooten, Sabine S; Cook, James M; Ryalls, James M W; Barton, Craig V M; Johnson, Scott N

    2018-04-27

    Animal mutualisms, which involve beneficial interactions between individuals of different species, are common in nature. Insect-insect mutualism, for example, is widely regarded as a keystone ecological interaction. Some mutualisms are anticipated to be modified by climate change, but the focus has largely been on plant-microbe and plant-animal mutualisms rather than those between animals. Ant-aphid mutualisms, whereby ants tend aphids to harvest their honeydew excretions and, in return, provide protection for the aphids, are widespread. The mutualism is heavily influenced by the quality and quantity of honeydew produced by aphids, which is directly affected by host plant quality. As predicted increases in concentrations of atmospheric carbon dioxide (eCO 2 ) are widely reported to affect plant nutritional chemistry, this may also alter honeydew quality and hence the nature of ant-aphid mutualisms. Using glasshouse chambers and field-based open-top chambers, we determined the effect of eCO 2 on the growth and nutritional quality (foliar amino acids) of lucerne (Medicago sativa). We determined how cowpea aphid (Aphis craccivora) populations and honeydew production were impacted when feeding on such plants and how this affected the tending behaviour of ants (Iridomyrmex sp.). eCO 2 stimulated plant growth but decreased concentrations of foliar amino acids by 29% and 14% on aphid-infested plants and aphid-free plants, respectively. Despite the deterioration in host plant quality under eCO 2 , aphids maintained performance and populations were unchanged by eCO 2 . Aphids induced higher concentrations of amino acids (glutamine, asparagine, glutamic acid and aspartic acid) important for endosymbiont-mediated synthesis of essential amino acids. Aphids feeding under eCO 2 also produced over three times more honeydew than aphids feeding under ambient CO 2 , suggesting they were imbibing more phloem sap at eCO 2 . The frequency of ant tending of aphids more than doubled in

  12. Gastronomia Molecular: Desconstruindo 20 anos de Uma Tendência

    Directory of Open Access Journals (Sweden)

    Joana Pellerano

    2013-06-01

    Full Text Available A gastronomia molecular gera interesse e controvérsia desde que foi criada, em 1992, nos workshops de Erice, na Itália. Da curiosidade dos cientistas Nicholas Kurti e Hervé This, que desenvolveram a disciplina, à aplicação prática encontrada por chefs de todo o mundo, a gastronomia molecular é perseguida por parecer ser mais complicada do que realmente é: o estudo meticuloso dos alimentos. O objetivo desse artigo é descrever o seu surgimento e o que trouxe ao cenário contemporâneo enquanto tendência gastronômica. Para tanto, foi realizada uma revisão bibliográfica em livros e citações na imprensa estrangeira, o que permitiu descrever os motivos para que essa forma de cozinhar cause tanta polêmica.

  13. A Pilot Study of Children’s Blood Lead Levels in Mount Isa, Queensland

    Directory of Open Access Journals (Sweden)

    Donna Green

    2017-12-01

    Full Text Available Mount Isa, Queensland, is one of three Australian cities with significant lead emissions due to nonferrous mining and smelting. Unlike the two other cities with lead mines or smelters, Mount Isa currently has no system of annual, systematic, community-wide blood lead level testing; and testing rates among Indigenous children are low. In previous screenings, this group of children has been shown to have higher average blood lead levels than non-Indigenous children. The first aim of this study was to assess whether parents and children would participate in less invasive, rapid point-of-care capillary testing. The second aim was to measure blood lead levels among a range of children that roughly reflected the percentage of the Indigenous/non-Indigenous population. This pilot study is based on a convenience sample of children between the ages of 12 and 83 months who were recruited to participate by staff at a Children and Family Centre. Over three half-days, 30 children were tested using capillary blood samples and the LeadCare II Point-of-Care testing system. Rapid point-of-care capillary testing was well tolerated by the children. Of 30 children tested, 40% (n = 12 had blood lead levels ≥5 µg/dL and 10% had levels ≥10 µg/dL. The highest blood lead level measured was 17.3 µg/dL. The percentage of children with blood lead levels ≥5 µg/dL was higher among Indigenous children compared to non-Indigenous (64.2% compared to 18.8% as was the geometric mean level (6.5 (95% CI, 4.7, 9.2 versus 2.4 (95% CI, 1.8, 3.1, a statistically significant difference. Though based on a small convenience sample, this study identified 12 children (40% of the sample with blood lead levels ≥5 µg/dL. Due to historical and ongoing heavy metal emissions from mining and smelting in Mount Isa, we recommend a multi-component program of universal blood lead level testing, culturally appropriate follow-up and intervention for children who are identified with blood lead

  14. A Pilot Study of Children's Blood Lead Levels in Mount Isa, Queensland.

    Science.gov (United States)

    Green, Donna; Sullivan, Marianne; Cooper, Nathan; Dean, Annika; Marquez, Cielo

    2017-12-13

    Mount Isa, Queensland, is one of three Australian cities with significant lead emissions due to nonferrous mining and smelting. Unlike the two other cities with lead mines or smelters, Mount Isa currently has no system of annual, systematic, community-wide blood lead level testing; and testing rates among Indigenous children are low. In previous screenings, this group of children has been shown to have higher average blood lead levels than non-Indigenous children. The first aim of this study was to assess whether parents and children would participate in less invasive, rapid point-of-care capillary testing. The second aim was to measure blood lead levels among a range of children that roughly reflected the percentage of the Indigenous/non-Indigenous population. This pilot study is based on a convenience sample of children between the ages of 12 and 83 months who were recruited to participate by staff at a Children and Family Centre. Over three half-days, 30 children were tested using capillary blood samples and the LeadCare II Point-of-Care testing system. Rapid point-of-care capillary testing was well tolerated by the children. Of 30 children tested, 40% ( n = 12) had blood lead levels ≥5 µg/dL and 10% had levels ≥10 µg/dL. The highest blood lead level measured was 17.3 µg/dL. The percentage of children with blood lead levels ≥5 µg/dL was higher among Indigenous children compared to non-Indigenous (64.2% compared to 18.8%) as was the geometric mean level (6.5 (95% CI, 4.7, 9.2) versus 2.4 (95% CI, 1.8, 3.1)), a statistically significant difference. Though based on a small convenience sample, this study identified 12 children (40%) of the sample with blood lead levels ≥5 µg/dL. Due to historical and ongoing heavy metal emissions from mining and smelting in Mount Isa, we recommend a multi-component program of universal blood lead level testing, culturally appropriate follow-up and intervention for children who are identified with blood lead levels ≥5

  15. Tend to Compare and Tend to Be Fair: The Relationship between Social Comparison Sensitivity and Justice Sensitivity.

    Science.gov (United States)

    Zhen, Shanshan; Yu, Rongjun

    2016-01-01

    Social comparison is a prerequisite for processing fairness, although the two types of cognition may be associated with different emotions. Whereas social comparison may induce envy, the perception of unfairness may elicit anger. Yet, it remains unclear whether people who tend to have a strong sense of fairness also tend to compare themselves more with others. Here, Study 1 used a modified ultimatum game (UG) and a social comparison game (SCG) to examine the relationship between justice sensitivity and social comparison sensitivity in 51 young adults. Study 2 examined self-reported social comparison and justice sensitivity in 142 young adults. Both studies showed a positive correlation between social comparison sensitivity and justice sensitivity. We reason that social comparison and justice sensitivity have an important positive correlation in human decision-making. The rejection of self-disadvantageous inequality offers may be due to the social comparison effect, which suggests that the tendency to compare oneself with others may contribute to having a strong sense of justice. Our findings suggest that the predictions of game theory may vary depending on the social culture context and incorporating notions of fairness and social comparison tendency may be essential to better predict the actual behavior of players in social interactive situations.

  16. Tend to Compare and Tend to Be Fair: The Relationship between Social Comparison Sensitivity and Justice Sensitivity.

    Directory of Open Access Journals (Sweden)

    Shanshan Zhen

    Full Text Available Social comparison is a prerequisite for processing fairness, although the two types of cognition may be associated with different emotions. Whereas social comparison may induce envy, the perception of unfairness may elicit anger. Yet, it remains unclear whether people who tend to have a strong sense of fairness also tend to compare themselves more with others. Here, Study 1 used a modified ultimatum game (UG and a social comparison game (SCG to examine the relationship between justice sensitivity and social comparison sensitivity in 51 young adults. Study 2 examined self-reported social comparison and justice sensitivity in 142 young adults. Both studies showed a positive correlation between social comparison sensitivity and justice sensitivity. We reason that social comparison and justice sensitivity have an important positive correlation in human decision-making. The rejection of self-disadvantageous inequality offers may be due to the social comparison effect, which suggests that the tendency to compare oneself with others may contribute to having a strong sense of justice. Our findings suggest that the predictions of game theory may vary depending on the social culture context and incorporating notions of fairness and social comparison tendency may be essential to better predict the actual behavior of players in social interactive situations.

  17. Vaccination with Clostridium perfringens recombinant proteins in combination with Montanide™ ISA 71 VG adjuvant increases protection against experimental necrotic enteritis in commercial broiler chickens

    Science.gov (United States)

    This study was performed to compare four Clostridium perfringens recombinant proteins as vaccine candidates using the Montanide™ ISA 71 VG adjuvant in an experimental model of necrotic enteritis. Broiler chickens were immunized with clostridial recombinant proteins with ISA 71 VG, and intestinal le...

  18. Gestión estratégica institucional: Caso ISA

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo Martínez Fajardo

    2003-12-01

    Full Text Available Desde la perspectiva histórica neoinstitucional, en el presente artículo se analiza la gestión estratégica de la empresa Interconexión Eléctrica S.A. (ISA, mostrando los principales elementos de los cambios institucionales, estratégicos, de estructura y resultados de la empresa desde mediados de la década de los noventa. Se destaca el desarrollo de capacidades organizacionales que le han permitido tener una clara ventaja competitiva en el sector eléctrico colombiano y una estrategia de desarrollo hacia el exterior, a través de la relativa posición favorable con respecto a empresas de países desarrollados.

  19. Tendências em medicina laboratorial Trends in laboratory medicine

    Directory of Open Access Journals (Sweden)

    Gustavo Aguiar Campana

    2011-08-01

    Full Text Available A patologia clínica/medicina laboratorial é uma especialidade direcionada à realização de exames complementares no auxílio ao diagnóstico, com impacto nos diferentes estágios da cadeia de saúde: prevenção, diagnóstico, prognóstico e acompanhamento terapêutico. Diversos elementos apontam para maior utilização da medicina diagnóstica no futuro. Para discutirmos as principais tendências na medicina laboratorial, descrevemos os fatores que colaboram e são fundamentais para o crescimento desse mercado denominados, neste estudo, drivers de crescimento. As principais tendências que terão forte impacto na medicina laboratorial, e que serão descritas neste artigo, são: ferramentas de gestão, inserção de novos testes no mercado e rol de procedimentos, qualidade dos serviços em medicina diagnóstica, modelos de operação, automação, consolidação e integração, tecnologia da informação, medicina personalizada e genética. Sabemos que a medicina diagnóstica demonstra sua importância ao participar de 70% das decisões clínicas, absorvendo uma pequena parte dos custos em saúde (cerca de 10%. Todas as tendências analisadas neste trabalho apontam para um crescimento na utilização dos exames laboratoriais e também para sua importância na cadeia de saúde. Esse novo posicionamento, somado às novas expectativas de alta resolubilidade, pressiona o mercado e as companhias que o compõem a buscar mudanças e novas estratégias de atuação.Clinical pathology/laboratory medicine, a specialty focused on performing complementary tests to aid diagnosis, has impact upon several stages of health care: prevention, diagnosis, prognosis, and therapeutic management. There are several factors that will foster the use of laboratory medicine in the future. In order to discuss the main trends in laboratory medicine, this article describes the major factors that have promoted growth in this market, which herein are referred to as growth

  20. Brote del virus ISA: crisis ambiental y capacidad de la institucionalidad ambiental para manejar el conflicto

    Directory of Open Access Journals (Sweden)

    Beatriz Bustos

    2012-09-01

    Full Text Available La industria salmonera chilena vivió recientemente una crisis de magnitud a partir de la aparición del virus ISA. El artículo examina esta situación, concentrándose en el papel que desempeña la ciencia en las soluciones políticas propuestas, como caso para discutir la capacidad de los mecanismos de gobernanza ambiental neoliberal para solucionar crisis ambientales y económicas. La pregunta que guía el trabajo es: ¿cuál fue el rol de la ciencia en la política ambiental para la industria? El argumento promovido es que la crisis representa un momento de reestructuración de la relación sociedad-naturaleza, en el cual se redefinieron mecanismos de propiedad, control y acceso a recursos naturales, pero en el que, pese al discurso neoliberal de confianza en los expertos y la ciencia como elementos de toma de decisiones, la información científica tuvo escasa relevancia.The Chilean salmon industry recently experienced a crisis due to an outbreak of the ISA virus. The article examines the crisis focusing on the role of science in the policy solutions proposed, to discuss the real capacity of neoliberal environmental governance mechanisms to solve environmental and economic crisis. The question guiding this research is, which was the role of science in environmental policy createdfor the salmon industry? The argument is that the crisis represents a reestructuring of the relationship between society and nature through the redefinition of property rights, control and access to natural resources, but in which, in spite of a neoliberal discourse of trust in experts and science as elements of decision making, scientific information had little relevance.

  1. The ISA 700 Auditor’s Report and the Audit Expectation Gap – Do Additional Explanations Matter?

    NARCIS (Netherlands)

    Gold, A.H.; Pott, C.; Gronewold, U.

    2012-01-01

    In this paper we test the effectiveness of explanations as mandated by the revised ISA 700 auditor's report in reducing the audit expectation gap. German auditors and financial statement users participated in an experiment where they read a summary of a firm's financial statements and an auditor's

  2. Efficient I/O Joining and Reliable Data Publication in Energy Harvested ISA100.11a Network

    NARCIS (Netherlands)

    Das, Kallol; Mathews, E.; Zand, P.; Sanchez Ramirez, Andrea; Havinga, Paul J.M.

    Energy harvesting technologies have brought a paradigm shift in the industrial automation sector by procreating self-powered wireless input/output (I/O) devices. Unfortunately, current wireless technologies for industrial applications, such as ISA100.11a and WirelessHART, are yet far from supporting

  3. Evaluation of working conditions of workers engaged in tending horses

    Directory of Open Access Journals (Sweden)

    Bożena Nowakowicz-Dębek

    2014-11-01

    Full Text Available [b]introduction[/b]. A growing interest in the horse business has resulted in the increased engagement of many people in this area, and the health problems occurring among workers create the need to search for prophylactic measures. [b]objective[/b]. The objective of the study was evaluation of the level of exposure to air pollution in a stable, and estimation of the degree of work load among workers engaged in tending horses. [b]material and methods[/b]. The study was conducted twice, during the winter season, in a stable maintaining race horses, and in a social room. In order to evaluate workers’ exposure, air samples were collected by the aspiration method. After the incubation of material, the total number of bacteria and fungi in the air was determined, as well as the number of aerobic mesophilic and thermophilic bacteria, expressed as the number of colony forming units per cubic meter of air (CFU/m[sup]3[/sup]. The measurement of total dust concentration in the air was also performed, simultaneously with the measurement of microclimatic parameters. The study of work load also covered the measurement of energy expenditure, evaluation of static physical load, and monotony of movements performed. [b]conclusions[/b]. The stable may be considered as a workplace with considerable risk of the occurrence of unfavourable health effects.

  4. Pinatubo Emulation in Multiple Models (POEMs): co-ordinated experiments in the ISA-MIP model intercomparison activity component of the SPARC Stratospheric Sulphur and it's Role in Climate initiative (SSiRC)

    Science.gov (United States)

    Lee, Lindsay; Mann, Graham; Carslaw, Ken; Toohey, Matthew; Aquila, Valentina

    2016-04-01

    The World Climate Research Program's SPARC initiative has a new international activity "Stratospheric Sulphur and its Role in Climate" (SSiRC) to better understand changes in stratospheric aerosol and precursor gaseous sulphur species. One component of SSiRC involves an intercomparison "ISA-MIP" of composition-climate models that simulate the stratospheric aerosol layer interactively. Within PoEMS each modelling group will run a "perturbed physics ensemble" (PPE) of interactive stratospheric aerosol (ISA) simulations of the Pinatubo eruption, varying several uncertain parameters associated with the eruption's SO2 emissions and model processes. A powerful new technique to quantify and attribute sources of uncertainty in complex global models is described by Lee et al. (2011, ACP). The analysis uses Gaussian emulation to derive a probability density function (pdf) of predicted quantities, essentially interpolating the PPE results in multi-dimensional parameter space. Once trained on the ensemble, a Monte Carlo simulation with the fast Gaussian emulator enabling a full variance-based sensitivity analysis. The approach has already been used effectively by Carslaw et al., (2013, Nature) to quantify the uncertainty in the cloud albedo effect forcing from a 3D global aerosol-microphysics model allowing to compare the sensitivy of different predicted quantities to uncertainties in natural and anthropogenic emissions types, and structural parameters in the models. Within ISA-MIP, each group will carry out a PPE of runs, with the subsequent analysis with the emulator assessing the uncertainty in the volcanic forcings predicted by each model. In this poster presentation we will give an outline of the "PoEMS" analysis, describing the uncertain parameters to be varied and the relevance to further understanding differences identified in previous international stratospheric aerosol assessments.

  5. Digital Workflow for the Conservation of Bahrain Built Heritage: the Sheik Isa Bin ALI House

    Science.gov (United States)

    Barazzetti, L.; Mezzino, D.; Santana Quintero, M.

    2017-08-01

    Currently, the commercial market offers several tools for digital documentation of historic sites and buildings. Photogrammetry and laser scanning play a fundamental role in the acquisition of metric information, which is then processed to generate reliable records particularly useful also in the built heritage conservation field. Although potentially very fast and accurate, such techniques require expert operators to produce reliable results, especially in the case of complex and large sites. The aim of this paper is to present the digital workflow developed for data acquisition and processing of the Shaikh Isa Bin Ali house in Muharraq, Bahrain. This historic structure is an outstanding example of Bahrain architecture as well as tangible memory of the country history, with strong connotations in the Bahrain cultural identity. The building has been documented employing several digital techniques, including: aerial (drone) and terrestrial photogrammetry, rectifying photography, total station and laser scanning. The documentation project has been developed for the Bahrain Authority for Culture and Antiquities (BACA) by a multidisciplinary team of experts from Carleton Immersive Media Studio (CIMS, Carleton University, Canada) and Gicarus Lab (Politecnico di Milano, Italy).

  6. Preparing our Future Teachers, a Paper for ISA Panel on Undergraduate Education.

    Science.gov (United States)

    Lovell, John P.

    College and university professors tend to be highly professional in regard to their academic discipline but not to their teaching role. This failure is due in part to the academic reward structure and in part to a general disdain for the pedagogical concerns of the schools of education. The impression held by graduate schools that there is nothing…

  7. THE EFFECT OF ENZYMATIC ADDITIVES ON THE PRODUCTIVITY OF LAYING HENS ISA BROWN

    Directory of Open Access Journals (Sweden)

    Branislav Gálik

    2011-01-01

    Full Text Available The aim of this work the influence of enzymatic additives on the productivity of laying hens ISA BROWN was to analyze. The experiment together with the Central Control and Testing Institute of Agriculture was realized. The experiment was conducted 11 months, in 3 phases: from the 22nd to the 28th week, from the 29th to the 46th week and from the 47th to the 68th week of production. Two groups with 1080 (540 in each group animals were examined (control group A, experimental group B. In the experiment diets based on wheat, rye, barley, soybean, minerals and vitamins were used. In group B we administered a feed mixture with endo-1,4-ß-xylanase (activity 7820 TXU.g-1 and endo-1,4-ß-glucanase (activity 2940 TGU.g-1 fortification. After finishing of the last period (68th week of hens´ age were registered parameters in both groups of animals. The body weight at the end of the experiment was positively affected in the second group (containing enzymes: B. This difference was significantly higher (P<0.05. In the B group was also confirmed significant better (P<0.05 feed intake (141.8 and 144.3 g respectively on the same level and non significant (P>0.05 heavier eggs (64.54 and 64.02 g respectively in A and B group. For hens in the control group (without enzymes, was registered significantly lower (P<0.05 body weight (2 239 and 2 307 g of hens, a lower weight of eggs (P>0.05, and higher feed intake (P<0.05. The feeding without enzymes in the A group negatively influenced the quality of eggs. It was higher percentage of total non-standard eggs (7.10 and 6.56 %, cracked eggs (4.0 and 3.64 % and broken eggs (0.52 and 0.39 %. The differences of these parameters are not significant (P>0.05. After the administration of the enzymes in the feed mixture fortification we determined a positive effect on laying hens´ productivity. The application of enzymes positively affected the average body weight of hens.

  8. Adverse events associated with vaccine prepared Ngcgm3 / Vssp / montanide Isa 51 In patients with breast cancer Metastatic

    International Nuclear Information System (INIS)

    Perez Machin, Maikel; Torre Santos, Ana V de la; Perez Ramirez, Kirenia; Marinello, Patricia; Suarez Martinez, Giselle

    2009-01-01

    Among the best-studied antigenic systems, which have their expression increased in the membrane of tumor cells, are the gangliosides. Several clinical trials with therapeutic vaccines containing N-glycolylated gangliosides have been made in Cuba by the Center Molecular Immunology. One of these studies, it is the trial: 'Specific active immunotherapy with the vaccine preparation NGcGM3 / VSSP / Montanide ISA 51 in the treatment of patients with breast cancer metastatic. Phase II'. In order to assess the major events events related to this product, were reviewed the medical records of total patients in the clinical trial performed in the service Oncology Hospital Universitario 'Celestino Hernandez Robau' Villa Clara. (Author)

  9. Twelfth ISAS national symposium on analytical techniques for safety and sufficiency of natural resources/products: technical papers

    International Nuclear Information System (INIS)

    Padmanabhan, P.K.; Page, A.G.

    1997-02-01

    This volume contains the proceedings of the ISAS (Indian Society of Analytical Scientists) national symposium. The main thrust of the symposium was on new fuel cycle technologies relevant to thorium utilisation programmes. The technologies for different separation processes, techniques for measurements of various process parameters and highly sensitive analytical methods for the determination of the chemical constituents were among the other topics covered. Quality upgradation, standardisation of methods and validation of measurements which are integral parts of product evaluation were also discussed. Papers relevant to INIS are indexed separately

  10. Kjubrikovo čitanje Bardžisa: Značaj kostima za razumevanje Paklene pomorandže

    OpenAIRE

    Dijana Metlić

    2016-01-01

    Roman Paklena pomorandža Entonija Bardžisa, objavljen 1962. godine, postao je jedno od kultnih književnih dela XX veka, pre svega zahvaljujući istoimenom filmu Stenlija Kjubrika iz 1971. Okarakterisan kao dekadentno i nihilističko ostvarenje, snimljen tako da gledaoci „uživaju“ u scenama nasilja, Kjubrikov film bio je, uz prekide, u distribuciji u Britaniji do 1974. godine kada je povučen na zahtev reditelja zbog optužbi koje su ga implicitno teretile za povećanje stepena delinkventskog nasil...

  11. 29 CFR 788.7 - “Planting or tending trees.”

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false âPlanting or tending trees.â 788.7 Section 788.7 Labor... MORE THAN EIGHT EMPLOYEES ARE EMPLOYED § 788.7 “Planting or tending trees.” Employees employed in “planting or tending trees” include those engaged in weeding, preparing firebreaks, removing “seeding...

  12. ESTRATEGIAS DE MARKETING MIX PARA AUMENTAR LAS VENTAS DE SERVICIOS EDUCATIVOS EN LA ESPECIALIDAD DE SECRETARIADO EJECUTIVO EN EL INSTITUTO SUPERIOR TECNOLOGICO ISA-CHICLAYO-2014.

    OpenAIRE

    Anastasio Vallejos, Carla Arleen; Universidad César Vallejos- Chiclayo

    2016-01-01

    La investigación lleva como título “Estrategias de marketing mix para aumentar las ventas de servicios educativos en la especialidad de secretariado ejecutivo en el Instituto Superior Tecnológico ISA-chiclayo-2014”, donde se tuvo como principal objetivo proponer estrategias de marketing mix para aumentar las ventas de servicios educativos en la especialidad de secretariado ejecutivo en el Instituto Superior Tecnológico ISA-Chiclayo. Para ello se realizó un estudio de tipo descriptivo – propos...

  13. Sentimento de felicidade em idosos: uma abordagem epidemiológica, ISA-Camp 2008 Happiness in the elderly: an epidemiological approach in the ISA-Camp 2008 study

    Directory of Open Access Journals (Sweden)

    Margareth Guimarães Lima

    2012-12-01

    Full Text Available O objetivo foi detectar fatores associados à felicidade na população idosa. O estudo é do tipo transversal, de base populacional, com dados de 1.431 idosos do ISA-Camp 2008. A amostragem foi probabilística, por conglomerado e em dois estágios. Foram estimadas as prevalências do sentimento de felicidade por todo o tempo, segundo variáveis sociais, demográficas, de comportamentos e condições de saúde. Os idosos que se sentem felizes por maior tempo são os casados, os que trabalham, são ativos ou insuficientemente ativos no lazer, ingerem bebida alcoólica ocasionalmente, consomem frutas, legumes e verduras todos os dias, não são obesos, apresentam um tempo de sono The objective was to identify factors associated with happiness in the elderly. A cross-sectional, population-based study was conducted in 1,431 elderly under the ISA-Camp 2008 project. The survey used a two-stage probabilistic cluster sample. Prevalence of happiness was measured over time according to socio-demographics variables, health behaviors, and health conditions. High prevalence of happiness was associated with: marital status (married, active working, activity and insufficient leisure-time activity, occasional consumption of alcoholic beverages, daily consumption of fruit, vegetables, and leafy vegetables, normal body mass index, and sleeping less than 10 hours/night and sleeping well. The highest prevalence of long-term happiness was observed among elderly with no reported illness, with better self-rated health, and with less disability. Happiness was strongly related to health indicators, suggesting the adequacy of complementary use of this indicator for evaluating health promotion programs in the elderly.

  14. Stimulus Control: The Sought or Unsought Influence of the Objects We Tend to

    Science.gov (United States)

    Morsella, Ezequiel; Larson, Lindsay R. L.; Zarolia, Pareezad; Bargh, John A.

    2011-01-01

    Does the mere presence of the things we have tended to influence our actions systematically, in ways that escape our awareness? For example, while entering a tool shed, does perceiving objects that we once tended to (e.g., tools, musical instruments) influence how we then execute a simple action (e.g., flicking the shed's light switch)? Ancient…

  15. [The role of science in policy making--EuSANH-ISA project, framework for science advice for health].

    Science.gov (United States)

    Cianciara, Dorota; Piotrowicz, Maria; Bielska-Lasota, Magdalena; Wysocki, Mirosław J

    2012-01-01

    Governments and other authorities (including MPs) should be well informed on issues of science and technology. This is particularly important in the era of evidence-based practice. This implies the need to get expert advice. The process by which scientific knowledge is transmitted, along with proposals how to solve the problem, is called science advice. The main aim of the article is to discuss the issue of science advice--definitions, interaction between science and policymaking, and its position in contemporary policies. The second aim is to present European Science Advisory Network for Health (EuSANH), EuSANH-ISA project, and framework for science advice for health which was developed by participants. Furthermore, the role of civil society in decision-making process and science advice is also discussed. Interaction between scientists and policy-makers are described in terms of science-push approach (technocratic model), policy-pull (decisionistic) and simultaneous push-pull approach (pragmatic). The position of science advice is described in historical perspective from the 50s, especially in the last two decades. Description relies to USA, Canada and UK. Principles of scientific advice to government (Government Office for Science, UK) are quoted. Some important documents related to science advice in EU and UN are mentioned. EuSANH network is described as well as EuSANH-ISA project, with its objectives and outcomes. According to findings of this project, the process of science advice for health should follow some steps: framing the issue to be covered; planning entire process leading to the conclusion; drafting the report; reviewing the report and revision; publishing report and assessing the impact on policy.

  16. [Effects of target tree tending on community structure and diversity in subtropical natural secondary shrubs].

    Science.gov (United States)

    Zhang, Hui; Zhou, Guo Mo; Bai, Shang Bin; Wang, Yi Xiang; You, Yu Jie; Zhu, Ting Ting; Zhang, Hua Feng

    2017-05-18

    The typical natural secondary shrub community was chosen in Lin'an of Zhejiang Pro-vince to discover its possibility of restoration to arbor forest with three kinds of forest management models being taken, i.e., no care as control, closed forest management and target tree tending. Over four years growth, compared with control, closed forest management significantly increased average DBH and height by 130% and 50%, respectively, while 260% and 110% for target tree tending. In target tree tending plots, larger trees had been emerging with 4.5-8.5 cm diameter class and 4.5-8.5 m height class and formed a new storey of 4 m compared with control. The species biodiversity indexes at shrub layer were significantly increased in closed management plots, and did not decrease in target tree tending plots. Closed forest management did not change the tree species composition, following its previous succession direction. However, target tree tending increased the importance value of target species with the high potential succession direction of mixed coniferous-broadleaved forest. The results revealed that the secondary shrub community with target tree tending achieved more desired goals on DBH and height growth of dominant trees and species composition improvement compared with closed management. If the secondary shrub community could be managed when the operational conditions existed, target tree tending model should be selected to accelerate the restoration of shrub toward arbor forest.

  17. The role of the International Society for Applied Ethology (ISAE) in the global development of animal welfare science and its relationship with the OIE; strength through partnership

    Science.gov (United States)

    The objective of this presentation is to introduce the ISAE and to highlight members’ roles in the development and implementation of OIE’s animal welfare standards. Animal welfare science is a young discipline. Originally, welfare science was heavily focused on animal behavior (ethology), but it is ...

  18. Märt Agu: "Isa vari käib mul kogu aeg kannul" / Märt Agu ; interv. Aigi Viira

    Index Scriptorium Estoniae

    Agu, Märt

    2006-01-01

    1. okt. tähistas oma 30-aastast sünnipäeva ja oma ellukutsuja Mait Agu 55-sünniaastapäeva Tallinna Ülikooli koreograafiaosakond. Sel puhul esitati Estonias Mait Agu tantsulavastus "Kodalased ja kaasaegsed", mille seadis uuesti lavale Märt Agu oma isa loodud koreograafia põhjal

  19. Dimensions of human ejaculated spermatozoa in Papanicolaou-stained seminal and swim-up smears obtained from the Integrated Semen Analysis System (ISAS(®)).

    Science.gov (United States)

    Bellastella, Giuseppe; Cooper, Trevor G; Battaglia, Marina; Ströse, Anda; Torres, Inma; Hellenkemper, Barbara; Soler, Carles; Sinisi, Antonio A

    2010-11-01

    Objective measurements are required for computer-aided sperm morphometric analysis (CASMA) machines to distinguish normal from abnormal sperm heads. The morphometric characteristics of spermatozoa in 72 samples of semen and of spermatozoa from 72 other semen samples after swim-up were quantified by the semi-automated Integrated Sperm Analysis System (ISAS) computer-aided system, which measured the sperm head parameters length (L), width (W), area (A), perimeter (P), acrosomal area (Ac), and the derived values L/W and P/A. For each man a homogeneous population of distributions characterized seminal spermatozoa (7 942 cells: median values L 4.4 μm, W 2.8 μm, A 9.8 μm(2), P 12.5 μm, Ac 47.5%, L/W 1.57, P/A 1.27), and there was no significant difference in within- and among-individual variation. Different men could have spermatozoa of significantly different dimensions. Head dimensions for swim-up spermatozoa from different men (4 812 cells) were similar to those in semen, differing only by 2%-5%. The values of L, W and L/W fell within the limits given by the World Health Organization (WHO). Although these samples were not biologically matched, linear mixed-effects statistical analyses permitted valid comparison of the groups. A subpopulation of 404 spermatozoa considered to fit the stringent criteria of WHO 'normal' seminal spermatozoa from both semen and swim-up were characterized by median values (and 95% confidence intervals) of L, 4.3 μm (3.8-4.9), W, 2.9 μm (2.6-3.3), A, 10.2 μm(2) (8.5-12.2), P, 12.4 μm (11.3-13.9), Ac, 49% (36-60), L/W, 1.49 (1.32-1.67) and P/A, 1.22 (1.11-1.35). These median values fall within the 95th centile confidence limits given by WHO, but the confidence intervals for L and W were larger. Although these differences in head dimensions among men and after swim-up could be detected by CASMA, the small differences make it unlikely that technicians would be able to distinguish them. The values could be used as default sperm head

  20. DOCUMENTACIÓN DE UNA PRUEBA DE BIODEGRADACIÓN BAJO DIGESTIÓN ANAEROBIA CON ISA S.88

    Directory of Open Access Journals (Sweden)

    PAOLA MARCELA CERTUCHE MUÑOZ

    2016-12-01

    Full Text Available This paper proposes the ISA 88 standard as a tool to standardize a biodegradation test, through systematic documentation of tests, which contributes to the reproducibility and repetitividad of the method. This standard was applied to the ISO 15985 test; after the implementation of the standard, the process model was formed of 3 stages, 14 and 78 shares operations; procedural control model was formed of 3 unit procedures, operations 14 and 78 phases; the physical model, was formed of 4 units with their respective modules and control equipment; the recipe control model was integrated by physical model and procedural model and defines the formulation of materials. The automation level´s cell is determined at level 0 (74% manual, semiautomatic 33% and 6% automatic. The difficulty level of operating phases was identified as (77% under, 17% regulate and 6% higher. Finally, are exposed the advantages of the use for the standard in terms of standardization, frame generation control, flexibility and automation diagnosis.

  1. Mid-crustal uranium and rare metal mineralisation in the Mount Isa Inlier: a genetic model for formation of orogenic uranium deposits

    OpenAIRE

    McGloin, Matthew

    2017-01-01

    Uranium mineralisation near Mount Isa in northwest Queensland, Australia, is widespread yet poorly understood. Within this region in the Western Fold Belt, one hundred and ninety uranium-rare metal occurrences are known. This uranium mineralisation is similar to worldwide examples of albitite-hosted or sodium-metasomatic uranium deposits, which host albite-carbonate ore zones enriched in incompatible elements. Various metal sources and ore-forming processes have been sugg...

  2. Performance Comparison of Wireless Sensor Network Standard Protocols in an Aerospace Environment: ISA100.11a and ZigBee Pro

    Science.gov (United States)

    Wagner, Raymond S.; Barton, Richard J.

    2011-01-01

    Standards-based wireless sensor network (WSN) protocols are promising candidates for spacecraft avionics systems, offering unprecedented instrumentation flexibility and expandability. Ensuring reliable data transport is key, however, when migrating from wired to wireless data gathering systems. In this paper, we conduct a rigorous laboratory analysis of the relative performances of the ZigBee Pro and ISA100.11a protocols in a representative crewed aerospace environment. Since both operate in the 2.4 GHz radio frequency (RF) band shared by systems such as Wi-Fi, they are subject at times to potentially debilitating RF interference. We compare goodput (application-level throughput) achievable by both under varying levels of 802.11g Wi-Fi traffic. We conclude that while the simpler, more inexpensive ZigBee Pro protocol performs well under moderate levels of interference, the more complex and costly ISA100.11a protocol is needed to ensure reliable data delivery under heavier interference. This paper represents the first published, rigorous analysis of WSN protocols in an aerospace environment that we are aware of and the first published head-to-head comparison of ZigBee Pro and ISA100.11a.

  3. Nordic Walking and the Isa Method for Breast Cancer Survivors: Effects on Upper Limb Circumferences and Total Body Extracellular Water - a Pilot Study.

    Science.gov (United States)

    Di Blasio, Andrea; Morano, Teresa; Napolitano, Giorgio; Bucci, Ines; Di Santo, Serena; Gallina, Sabina; Cugusi, Lucia; Di Donato, Francesco; D'Arielli, Alberto; Cianchetti, Ettore

    2016-12-01

    The negative side effects of breast cancer treatments can include upper limb lymphoedema. The growing literature indicates that Nordic walking is an effective discipline against several disease symptoms. The aim of this study was to determine whether introduction to Nordic walking alone is effective against total body extracellular water and upper limb circumferences in breast cancer survivors compared to its combination with a series of specifically created exercises (i.e. the Isa method). 16 breast cancer survivors (49.09 ± 2.24 years) were recruited and randomly assigned to 1 of 2 different training groups. 10 lessons on Nordic walking technique plus the Isa method significantly reduced both extracellular body water and the extracellular-to-total body water ratio (p = 0.01 for both), and also the circumference of the upper limb, (both relaxed arm and forearm circumferences) (p = 0.01 for all), whereas Nordic walking alone did not. Introduction to Nordic walking does not seem to affect lymphoedema in breast cancer survivors. This might be because novice Nordic Walkers do not adequately generate an effective muscular pump through coordination of the alternated bimanual open-close cycle. The Isa method appears to close this gap.

  4. Ethological parameters and performance of Hy Line W-98 and ISA Brown hens when housed in furnished cages Parâmetros etológicos e desempenho de poedeiras Hy line W-98 e Isa Brown alojadas em gaiolas enriquecidas

    Directory of Open Access Journals (Sweden)

    V.F.B. Roll

    2008-06-01

    Full Text Available This study was carried out throughout a laying period to compare the behaviour and performance of two groups of commercial layers, 180 ISA Brown and 120 Hy line W98, housed at 17 weeks of age in furnished cages with a nest box, perches, dust-bath, and claw shortening device. Based on productive parameters, the model of furnished cages studied is suitable for both, Isa Brown and Hy line hens. The study suggested that strain has a significant effect on feather condition and on some behavioural displays, particularly those related to the use of a dust-bath.Durante um ciclo completo de postura foram avaliados o comportamento e o desempenho de duas linhagens de poedeiras comerciais, 180 ISA Brown e 120 Hy line W98, alojadas com 17 semanas de idade em gaiolas enriquecidas com ninho, poleiros, banho de areia e dispositivos de desgaste de unhas. Em ambas as linhagens, Isa Brown e Hy line W98, o modelo de gaiola estudado foi apropriado em termos de desempenho produtivo. O estudo sugeriu que a linhagem teve efeito significativo sobre a condição da plumagem e sobre alguns aspectos comportamentais, particularmente, aqueles relacionados ao uso do banho de areia.

  5. Kjubrikovo čitanje Bardžisa: Značaj kostima za razumevanje Paklene pomorandže

    Directory of Open Access Journals (Sweden)

    Dijana Metlić

    2016-07-01

    Full Text Available Roman Paklena pomorandža Entonija Bardžisa, objavljen 1962. godine, postao je jedno od kultnih književnih dela XX veka, pre svega zahvaljujući istoimenom filmu Stenlija Kjubrika iz 1971. Okarakterisan kao dekadentno i nihilističko ostvarenje, snimljen tako da gledaoci „uživaju“ u scenama nasilja, Kjubrikov film bio je, uz prekide, u distribuciji u Britaniji do 1974. godine kada je povučen na zahtev reditelja zbog optužbi koje su ga implicitno teretile za povećanje stepena delinkventskog nasilja u Engleskoj, neposredno po bioskopskom prikazivanju filma. Ovaj tekst analizira specifičan Kjubrikov pristup adaptaciji književnog predloška, sa pozicije upotrebe filmskog kostima i umetničkih dela pop arta u njegovoj scenografiji, što postaju ključni elementi za konstruisanje nove slike budućeg društva, nastalog u periodu hladnoratovske krize, Vijetnamskog rata i učestalih protesta omladine nezadovoljne uslovima života koji im obezbeđuju njihovi očevi. U pitanju je klasno određen svet, korumpiran i sumoran, ispražnjen i bez vitalnosti. Bardžis predstavlja Englesku neposredno po završetku sukoba između modsa i rokera šezdesetih godina, a pre pojave pank pokreta u drugoj polovini sedamdesetih. Takvoj apokaliptičkoj viziji britanske budućnosti suprotstavlja se jaka i osvešćena individua oličena u harizmatičnom junaku Aleksu Dilarču, koji sa Kjubrikom konačno dobija i svoj „stvarni“, oživotvoreni lik zahvaljujući Malkolmu Mekdauelu koji tumači glavnu ulogu.

  6. Heritability of Tpeak-Tend Interval and T-wave Amplitude: A Twin Study

    DEFF Research Database (Denmark)

    Haarmark, Christian; Kyvik, Kirsten O; Vedel-Larsen, Esben

    2011-01-01

    BACKGROUND: -Tpeak-Tend interval (TpTe) and T-wave amplitude (Tamp) carry diagnostic and prognostic information regarding cardiac morbidity and mortality. Heart rate and QT interval are known to be heritable traits. The heritability of T-wave morphology parameters such as TpTe and Tamp is unknown...... interval, QTpeak and QTend interval) were measured and averaged over three consecutive beats in lead V5. TpTe was calculated as the QTend and QTpeak interval difference. Heritability was assessed using structural equation models adjusting for age, gender and BMI. All models were reducible to a model...... of additive genetics and unique environment. All variables had considerable genetic components. Adjusted heritability estimates were: TpTe 46%, Tamp lead V1 34%, Tamp lead V5 47%, RR interval 55%, QT interval 67% and QTcB 42%. CONCLUSIONS: -RR interval, QT-interval, T-wave amplitude and Tpeak-Tend interval...

  7. Predatory behavior of Pseudodorus clavatus (Diptera, Syrphidae on aphids tended by ants

    Directory of Open Access Journals (Sweden)

    Alexandra Bächtold

    2013-12-01

    Full Text Available Predatory behavior of Pseudodorus clavatus (Diptera, Syrphidae on aphids tended by ants. In this study, we examined the interactions between myrmecophilous aphids, their ant-guards and a predatory syrphid species, Pseudodorus clavatus (F.. Larvae of this predator were found in the colonies of three aphid species: Aphis gossypii, A. spiraecola and Toxoptera sp., which were tended by eight ant species, especially Camponotus. Hoverfly larvae managed to infiltrate the aphid colonies and consume nymphs. Predator larvae exhibited inconspicuous movements and were not detected by ants which were commonly observed touching and antennating the larvae they come into contact. These results suggest that behavioral and chemical cues are involved in the infiltration and on the successful predation of syrphids upon aphids.

  8. Factors That May Tend to Limit the Religious Education of Recruits

    Science.gov (United States)

    1992-05-01

    chaplains also mentioned the following as tending to limit recruit religious education : (1) a lack of adequate chapel facilities , (2) not enough chaplains...inadequate chapel facilities at Recruit Training Command for recruit worship and religious education . This is a particular concern for the Catholic and... education . Procedures Data was gathered by distributing questionnaires to members of Division Six on October 22-23, 1991. Participation was voluntary

  9. Serum carcinoembryonic antigen tends to decrease in poorly-differentiated colorectal cancer

    Directory of Open Access Journals (Sweden)

    Ester Morina Silalahi

    2015-12-01

    This was a cross-sectional study conducted on 40 CRC subjects from July 2012 until May 2013. Determination of serum CEA and CA 19-9 levels and histopathological (cellular differentiation grades in CRC biopsies was done in all subjects. RESULTS The study involved forty CRC patients, consisting of 22 males and 18 females, with mean age of 51.93 ± 11.63 years, CEA levels of 51.93 ± 84.07 ng/ml and CA 19-9 levels of 33.81 ± 62.39 U/ml. Carcino-embryonic antigen levels tended to decrease with decreasing CRC histopathological grade, while CA 19-9 levels increased in well-differentiated CRC. However, both relationships were statistically not significant (with p=0.314 and p=0.787, respectively. CONCLUSIONS Carcinoembryonic antigen (CEA levels tend to decrease with decreasing histopathological grade of CRC, and CA 19-9 levels tend to increase in well-differentiated CRC.

  10. Comparação das estimativas de prevalência de indicadores de saúde no Município de Campinas, São Paulo, Brasil, nos anos de 2001/2002 (ISA-SP e 2008/2009 (ISA-Camp Comparación de las estimaciones de prevalencia en los indicadores de salud en Campinas, São Paulo, Brasil, durante los años 2001/2002 (ISA-SP y 2008/2009 (ISA-Camp Comparison of prevalence estimates for health indicators in Campinas, São Paulo State, Brazil, in 2001-2002 (ISA-SP and 2008-2009 (ISA-Camp

    Directory of Open Access Journals (Sweden)

    Chester Luis Galvão César

    2013-06-01

    Full Text Available O objetivo do estudo foi comparar estimativas da prevalência de indicadores de saúde para adultos residentes em Campinas, São Paulo, Brasil, utilizando dados de inquéritos domiciliares realizados em diferentes períodos de tempo (ISA-SP 2001/2002 e ISA-Camp 2008/2009, com amostras de 941 e 2.637 indivíduos de 18 anos e mais, respectivamente. Variáveis sociodemográficas caracterizaram a população estudada. Foram estimadas prevalências e seus respectivos intervalos de 95% de confiança e as comparações foram realizadas pelas razões de prevalência ajustadas por sexo, idade e escolaridade, obtidas pela regressão de Poisson com variância robusta. Diferenças estatisticamente significantes foram observadas para as prevalências de: morbidade referida, uso de medicamentos, percentual dos que nunca fumaram, realização dos exames de Papanicolaou e de mamografia, alguma vez na vida. O acompanhamento de indicadores de saúde por inquéritos repetidos em uma mesma população pode facilitar o monitoramento de objetivos e metas fornecendo subsídios ao planejamento de ações em saúde.El objetivo del estudio fue comparar las estimaciones de prevalencia en los indicadores de salud para los adultos que viven en Campinas, São Paulo, Brasil, con datos de encuestas de diferentes períodos de tiempo (ISA-SP 2001/2002 y ISA-Camp 2008/2009, con muestras de 941 y 2.637 personas de 18 años y más, respectivamente. Las variables sociodemográficas caracterizaron a la población de estudio. Se estimaron la prevalencia y sus respectivos intervalos de confianza del 95% y las comparaciones se realizaron por razones de prevalencia ajustadas por sexo, edad y educación, obtenidas mediante la regresión de Poisson. Se observaron diferencias estadísticas en la prevalencia de morbilidad, uso de medicamentos, el porcentaje de quienes nunca habían fumado, la realización de citologías vaginales y mamografías, en algún momento de sus vidas. El seguimiento

  11. Simpsonite isa / Margit Tõnson

    Index Scriptorium Estoniae

    Tõnson, Margit, 1978-

    2007-01-01

    Joonisfilmi "Simpsonite film" ("The Simpsons Movie") maailmaesilinastuste puhul seriaali looja, Kanada päritolu Matt Groeningist ja tema loodud seriaali populaarsuse fenomenist. Lisaks filmi süzheest "Mees peab oma naist kuulama!" (režissöör David Silverman)

  12. ISA 2011 Workshop Report

    DEFF Research Database (Denmark)

    Kulik, Lars; Guting, Ralf Hartmut; Lu, Hua

    2012-01-01

    Large indoor spaces such as office complexes and shopping malls have become an important part of our daily lives and research into indoor space is increasingly attracting attention from academia and industry. Indoor space differs from outdoor space in several important aspects such as layout...... often involves the third dimension as office buildings and shopping malls typically have several floors....

  13. Suri fetishismi isa

    Index Scriptorium Estoniae

    1999-01-01

    New Yorgis suri kunstnik ja koomiksite joonistaja, pärastsõja-aegse Ameerika bondage-erootika illustraator Eric Stanton. Paar aastat tagasi avaldas Saksa kirjastus Taschen Stantoni elust ja loomingust raamatu, mille toimetas erootikafotograaf Eric Kroll

  14. Soy-isoflavone supplementation tends to reduce menopausal symptoms in postmenopausal women

    Directory of Open Access Journals (Sweden)

    Raditya Wratsangka

    2013-08-01

    Full Text Available Background Menopausal symptoms in postmenopausal women tend to decrease health-related quality of life (HRQoL. The present study’s objective was to determine the effect of daily supplementation of 100 mg soy isoflavones on menopausal symptoms of healthy postmenopausal women. Isoflavones are phytoestrogens abundantly found in soy beans, and several studies have demonstrated that isoflavones are the best among the phytoestrogens. Methods The study was a community-based double blind randomized controlled trial involving 60 healthy postmenopausal women, aged between 48–60 years, in the Mampang Prapatan District, South Jakarta. Participants were block-randomized to receive either 100 mg soy-isoflavone + 500 mg calcium carbonate (intervention group or 500 mg calcium carbonate only (control group. Both supplements were taken daily for 12 weeks, from January to April 2010. Menopausal symptoms (measured by Menopause Rating Scale questionnaire were assessed at baseline and after supplementation. Chi-square test was used to examine the effect of soy isoflavone supplementation on menopausal symptoms. Results Fifty-six (93.3% of participants completed the study. There were no statistically significant differences (p>0.05 in the prevalence of menopausal symptoms between the isoflavone group and the control group. However, supplementation of soy isoflavones for 12 weeks tended to decrease the prevalence of menopausal symptoms in women with normal body mass index and adequate daily dietary isoflavone intake. Conclusion Daily supplementation of 100 mg soy isoflavones for 12 weeks tend to decrease the incidence of menopausal symptoms in postmenopausal women.

  15. The TENDL neutron data library and the TEND1038 38-group neutron constant system

    International Nuclear Information System (INIS)

    Abramovich, S.N.; Gorelov, V.P.; Gorshikhin, A.A.; Grebennikov, A.N.; Il'in, V.N.; Krut'ko, N.A.; Farafontov, G.G.

    2002-01-01

    The library contains neutron data for 103 nuclei - i.e. for 38 actinide nuclei (from 232 Th to 249 Cm), 26 fission fragment nuclei and 39 nuclei in structural and technological materials. The 38-group constants were obtained from TENDL. The high-energy group boundary is 20 MeV. The energy range below 1.2 eV contains 11 groups. Temperature and resonance effects were taken into account. The delayed neutron parameters for 6 groups and the yields of 40 fission fragments were obtained (light and heavy, stable and non-stable). The fast neutron features of spherical critical assemblies were calculated using constants from TEND1038. (author)

  16. Modelos matemáticos para estimar as exigências de lisina digestível para aves de corte ISA Label Mathematical models to estimate digestible lysine of ISA Label broilers

    Directory of Open Access Journals (Sweden)

    Jefferson Costa de Siqueira

    2009-09-01

    Full Text Available O objetivo neste estudo foi avaliar diferentes modelos ajustados às respostas de ganho de peso obtidas em experimento com aves da linhagem ISA Label no período de 1 a 28 dias de idade. Foram utilizados 480 pintos de ambos os sexos, distribuídos em delineamento inteiramente casualizado, em arranjo fatorial 4 X 2 (níveis de lisina X sexo, com três repetições, com 20 aves por unidade experimental. Uma ração basal foi formulada para atender às exigências das aves, exceto em lisina. Essa ração foi suplementada com L-lisina HCl em substituição ao ácido L-glutâmico, resultando em rações experimentais isonitrogênicas e isoenergéticas contendo 0,85; 0,97; 1,09 e 1,21% de lisina digestível. As respostas de ganho de peso foram ajustadas de acordo com os níveis de lisina da ração pelos modelos Linear Reponse Plateau (LRP, segmentado de duas inclinações, polinomial quadrático e exponencial. A primeira intersecção da equação quadrática com o platô do LRP também foi utilizado para estimar o nível ótimo. Os níveis de lisina digestível estimados pelos modelos LRP, segmentado e quadrático, foram 0,999; 1,010 e 1,116%, respectivamente. Na combinação do modelo quadrático com o LRP, a estimativa da exigência de lisina digestível foi de 1,041%. O modelo exponencial proporcionou estimativa de 1,066%, considerando 95% da resposta assintótica. Com base nos custos com alimentação, esse mesmo modelo gerou estimativas de 1,000 e 1,030% quando o custo do quilograma de L-lisina HCl foi R$ 8,50 e R$ 6,50, respectivamente. Considerando as limitações de cada um dos modelos propostos, o procedimento para estimar as exigências de lisina digestível pela primeira intersecção da equação quadrática com o platô do LRP foi o mais adequado para melhorar o ganho de peso das aves quando variáveis econômicas não foram consideradas.The objective of this study was to evaluate different models in the adjustment of weight gain (WG

  17. Egg quality and blood parameters of “Bianca di Saluzzo” and Isa Brown hens kept under free range conditions

    Directory of Open Access Journals (Sweden)

    Luca Doglione

    2010-01-01

    Full Text Available Egg quality traits and some blood parameters of Bianca di Saluzzo hen (BSh were compared to Isa Brown hen (IBh. Birds were reared in free range conditions. Weightofthewholeegg Weight of the whole egg was higher (P≤0.01 for IBh, due to its higher amount of albumen (P≤0.01 whereas BSh egg showed the highest weight and relative percentage of yolk (PP≤0.01. IBh and BSh egg chemical composition was similar.Totalredcellsdidnotshowstatisticaldifferencesbetweengroups,whiletotalleucocytes Total red cells did not show statistical differences between groups, while total leucocytes were lower (P≤0.05 forBShhens. Heterophyl/Lymphocyte(H/L ratioof BShwaslower (P for BSh hens. Heterophyl/Lymphocyte(H/L ratioof BShwaslower (P . Heterophyl/Lymphocyte(H/L ratioof BShwaslower (P Heterophyl/Lymphocyte (H/L ratio of BSh was lower (P (PP≤0.01 than IBh(0.33 IBh (0.33 (0.33 vs. 0.82.IBh 0.82. IBh IBh α-1 acid glycoprotein (AGPmeanconcentrationswereaffectedbytime: (AGP mean concentrations were affected by time: the values registered after 15 d (T1 and 2 months (T2 of observation were similar (345±132 and 279±58 μg/mlrespectively,whileAGPvalueregisteredafter4months(T3weresignificantlyhigher μg/ml respectively,whileAGPvalueregisteredafter4months(T3weresignificantlyhigher , while AGP value registered after 4 months (T3 were significantly higher (700±487 μg/ml;BShdidnotdisplayanyAGPstatisticalvariationovertime.IBhalbuminmeancon- μg/ml; BShdidnotdisplayanyAGPstatisticalvariationovertime.IBhalbuminmeancon- BSh did not display any AGP statistical variation over time. IBh albumin mean con- centration (1.62 g/dL was statistically lower than BSh values (1.89 g/dL; in both groups no effect of time of sampling was recorded. Acutephaseprotein(APPvaluesofBShsuggestedamoreadaptive Acute phase protein (APPvaluesofBShsuggestedamoreadaptive (APP values of BSh suggested a more adaptive attitude to free range conditions and appeared more constant over time. The present

  18. Desinserción espontánea y bilateral del tendón cuadricipital.

    Directory of Open Access Journals (Sweden)

    Jesuan Zordan

    2016-02-01

    Full Text Available La ruptura espontánea bilateral del tendón cuadricipital es una patología infrecuente (<5% de todas las rupturas cuadricipitales. El mayor número de casos reportados, se asocia a insuficiencia renal crónica,  obesidad, diabetes, lupus eritematoso sistémico, vasculitis e hiperparatiroidismo. Nuestro paciente, de 41 años de edad presenta insuficiencia renal crónica en tratamiento con hemodiálisis desde hace 8 años, asociada a hiperparatiroidismo secundario. Ingresa a nuestro servicio por incapacidad a la extensión de ambos miembros inferiores, tras incorporarse desde una silla, destacando en el examen físico una depresión palpable suprarrotuliana. Se realizan radiografías de ambas rodillas frente y perfil, ecografía de zona suprarrotuliana y resonancia magnética nuclear. Al  constatar lesión bilateral a nivel del tendón cuadricipital, se programa su reparación quirúrgica, la cual se realizó por cuestiones ajenas a nuestro servicio a los 30 días del diagnóstico. Se intervinieron de manera simultánea ambas rodillas utilizando como técnica, tunelización patelar y empleando suturas no reabsorbible. Se obtuvo un resultado excelente en ambos miembros inferiores según el Score Knee Society (S.N.S..

  19. Información en el proceso de toma de decisiones estratégicas en las empresas colombianas del grupo empresarial ISA

    OpenAIRE

    Montoya López, Jorge Eduardo

    2005-01-01

    113 p. En el proyecto de investigación se realizó inicialmente una exploración de las bases teóricas y empíricas del uso de la información en la toma de decisiones estratégicas, luego se indagó sobre el uso de la información en las decisiones estratégicas efectuadas recientemente en las empresas colombianas del grupo empresarial ISA, enfocándose en determinar la información utilizada desde un medio electrónico y concluyendo acerca de las reales posibilidades del apoyo de los sistemas de in...

  20. Tendências de teses e dissertações sobre ensino de astronomia no Brasil

    Science.gov (United States)

    Bretones, P. S.; Megid Neto, J.

    2003-08-01

    Neste trabalho são apresentados os resultados de uma pesquisa do tipo estado da arte sobre teses e dissertações defendidas no Brasil e relativas ao ensino de Astronomia. Teve por objetivo identificar essa produção e conhecer as principais tendências da pesquisa nesse campo. O procedimento inicial consistiu de um levantamento bibliográfico junto ao Centro de Documentação em Ensino de Ciências (CEDOC) da Faculdade de Educação da UNICAMP e ao Banco de Teses da CAPES disponível na Internet. Foram localizadas 13 dissertações de mestrado e 3 teses de doutorado, as quais foram estudadas em função dos seguintes aspectos: instituição, ano de defesa, nível escolar abrangido no estudo, foco temático do estudo e gênero de trabalho acadêmico. Deste conjunto de pesquisas, 13 (81,3%) delas foram defendidas a partir da segunda metade dos anos 90, indicando uma preocupação mais recente com temas relativos ao ensino de Astronomia no conjunto da produção acadêmica em programas de pós-graduação no Brasil. Verificou-se que 43,7% dos trabalhos foram produzidas na USP e 18,8% na UNICAMP. Quanto ao nível escolar abrangido nos estudos, predominaram os estudos direcionados ao Ensino Fundamental de 5a a 8a séries (62,5%). No que diz respeito ao foco temático das pesquisas, as principais tendências voltaram-se: 56,3% para Conteúdo e Método; 43,8% para Concepções do Professor; 37,5% para Currículo e Programas; 37,5% para Recursos Didáticos. Quanto ao gênero de trabalho acadêmico, verificou-se que 43,8% são de Pesquisa Experimental e 31,3% de Pesquisa de Análise de Conteúdo. Estudos de revisão bibliográfica como este visam colaborar com a divulgação ampla da produção acadêmica em determinada área, traçando algumas de suas tendências. Ao mesmo tempo possibilita, a partir de investigações decorrentes, apontar as suas contribuições para o ensino e sinalizar com necessidades a serem supridas por futuras pesquisas.

  1. Tendências de gerenciamento de unidades de saúde e de pessoas

    Directory of Open Access Journals (Sweden)

    Adriana Maria André

    2013-02-01

    Full Text Available OBJETIVO: Identificar que fatores produzem novas tendências no gerenciamento das unidades básicas de saúde e mudanças nos modelos de gestão. MÉTODOS: Estudo prospectivo com dez gestores de unidades de saúde e dez especialistas da área de saúde de São Paulo, SP, em 2010. Foi adotada a metodologia Delphi. Foram utilizadas quatro rodadas para a coleta de dados, três quantitativas e a quarta qualitativa. Nas três primeiras foram levantadas as tendências de mudança nos modelos de gestão; no perfil do gestor e nas competências requeridas para a função, foi utilizado o teste estatístico de Mann Whitney. A quarta rodada ocorreu por meio de um painel com os envolvidos, tendo sido escolhida a análise temática. RESULTADOS: Foram identificados os principais fatores que estão impulsionando o gerenciamento das unidades básicas de saúde, como as mudanças nos modelos de gestão. Foi consenso de que as dificuldades no gerenciamento das equipes e nas políticas influemciam nesse processo. Verificou-se que os gestores estão a par das tendências do macrocontexto com o advento das organizações sociais de saúde, mas ainda não estão se antecipando nas ações institucionais. CONCLUSÕES: A formação acadêmica deve ser revista não só quanto aos conteúdos, mas quanto ao desenvolvimento desses profissionais. O recrutamento, a seleção, o desenvolvimento e a avaliação devem ser norteados por essas competências alinhadas à missão, à visão, aos valores e aos modelos de gestão das organizações no contexto do Sistema Único de Saúde.

  2. Iodine Replete among Populations in Nigeria: Is the Population Tending Towards the Development of Iodine Induced Hyperthyroidism (IIH?

    Directory of Open Access Journals (Sweden)

    Onyeaghala A. Augustine

    2017-01-01

    Full Text Available Iodine is a micronutrient which is required for normal thyroid function. The recommended daily intake for iodine is 150 µg, however in pregnant women; higher levels up to 250 µg could be required. Deficiency of iodine in any given population results in iodine deficiency disorder (IDD. Researchers in Nigeria as far back as 1967 had reported the existence of IDD. To combat this public health problem with its associated medical consequences, a policy to ensure salt iodization was enacted. The Nation’s consistent approach to combat IDD was globally recognized and it was adjudged as the only country in Africa that had achieved the goals of sustained elimination of IDD. Although the health benefits derivable from salt iodization seem to outweigh its risk, yet recent epidemiological data are pointing that populations within the country could be tending toward the development of Iodine Induced Hyperthyroidism (IIH, a common disorder associated with salt iodization following chronic iodine deficiency. The need therefore to use evidence based approach to re-examine the County’s iodization policy as well as investigate the impact of salt iodization on thyroid hormone formation, metabolism and associated pathologies becomes very imperative. This could be very helpful in order to prevent the burden of non- communicable disease in a nation already battling with epidemics of various infectious diseases.

  3. Phosphotyrosine signaling proteins that drive oncogenesis tend to be highly interconnected.

    Science.gov (United States)

    Koytiger, Grigoriy; Kaushansky, Alexis; Gordus, Andrew; Rush, John; Sorger, Peter K; MacBeath, Gavin

    2013-05-01

    Mutation and overexpression of receptor tyrosine kinases or the proteins they regulate serve as oncogenic drivers in diverse cancers. To better understand receptor tyrosine kinase signaling and its link to oncogenesis, we used protein microarrays to systematically and quantitatively measure interactions between virtually every SH2 or PTB domain encoded in the human genome and all known sites of tyrosine phosphorylation on 40 receptor tyrosine kinases and on most of the SH2 and PTB domain-containing adaptor proteins. We found that adaptor proteins, like RTKs, have many high affinity bindings sites for other adaptor proteins. In addition, proteins that drive cancer, including both receptors and adaptor proteins, tend to be much more highly interconnected via networks of SH2 and PTB domain-mediated interactions than nononcogenic proteins. Our results suggest that network topological properties such as connectivity can be used to prioritize new drug targets in this well-studied family of signaling proteins.

  4. A Psicologia Social contemporânea: principais tendências e perspectivas nacionais e internacionais

    OpenAIRE

    Ferreira, Maria Cristina

    2010-01-01

    O presente trabalho faz um balanço do estado atual da Psicologia Social, no plano nacional e internacional. Para tanto, faz uma revisão inicial das principais tendências que marcaram a evolução da Psicologia Social na América do Norte, para, em seguida, apresentar as características atuais mais relevantes dessa disciplina na América do Norte, na Europa e na América Latina. Em seguida, detém-se na análise da recente produção brasileira em Psicologia Social. À guisa de conclusão, discute os des...

  5. Robotic and Human-Tended Collaborative Drilling Automation for Subsurface Exploration

    Science.gov (United States)

    Glass, Brian; Cannon, Howard; Stoker, Carol; Davis, Kiel

    2005-01-01

    Future in-situ lunar/martian resource utilization and characterization, as well as the scientific search for life on Mars, will require access to the subsurface and hence drilling. Drilling on Earth is hard - an art form more than an engineering discipline. Human operators listen and feel drill string vibrations coming from kilometers underground. Abundant mass and energy make it possible for terrestrial drilling to employ brute-force approaches to failure recovery and system performance issues. Space drilling will require intelligent and autonomous systems for robotic exploration and to support human exploration. Eventual in-situ resource utilization will require deep drilling with probable human-tended operation of large-bore drills, but initial lunar subsurface exploration and near-term ISRU will be accomplished with lightweight, rover-deployable or standalone drills capable of penetrating a few tens of meters in depth. These lightweight exploration drills have a direct counterpart in terrestrial prospecting and ore-body location, and will be designed to operate either human-tended or automated. NASA and industry now are acquiring experience in developing and building low-mass automated planetary prototype drills to design and build a pre-flight lunar prototype targeted for 2011-12 flight opportunities. A successful system will include development of drilling hardware, and automated control software to operate it safely and effectively. This includes control of the drilling hardware, state estimation of both the hardware and the lithography being drilled and state of the hole, and potentially planning and scheduling software suitable for uncertain situations such as drilling. Given that Humans on the Moon or Mars are unlikely to be able to spend protracted EVA periods at a drill site, both human-tended and robotic access to planetary subsurfaces will require some degree of standalone, autonomous drilling capability. Human-robotic coordination will be important

  6. Performance Comparison of Wireless Sensor Network Standard Protocols in an Aerospace Environment: ISA100.11a and ZigBee

    Science.gov (United States)

    Wagner, Raymond S.; Barton, Richard J.

    2011-01-01

    Wireless Sensor Networks (WSNs) can provide a substantial benefit in spacecraft systems, reducing launch weight and providing unprecedented flexibility by allowing instrumentation capabilities to grow and change over time. Achieving data transport reliability on par with that of wired systems, however, can prove extremely challenging in practice. Fortunately, much progress has been made in developing standard WSN radio protocols for applications from non-critical home automation to mission-critical industrial process control. The relative performances of candidate protocols must be compared in representative aerospace environments, however, to determine their suitability for spaceflight applications. In this paper, we will present the results of a rigorous laboratory analysis of the performance of two standards-based, low power, low data rate WSN protocols: ZigBee Pro and ISA100.11a. Both are based on IEEE 802.15.4 and augment that standard's specifications to build complete, multi-hop networking stacks. ZigBee Pro targets primarily the home and office automation markets, providing an ad-hoc protocol that is computationally lightweight and easy to implement in inexpensive system-on-a-chip components. As a result of this simplicity, however, ZigBee Pro can be susceptible to radio frequency (RF) interference. ISA100.11a, on the other hand, targets the industrial process control market, providing a robust, centrally-managed protocol capable of tolerating a significant amount of RF interference. To achieve these gains, a coordinated channel hopping mechanism is employed, which entails a greater computational complexity than ZigBee and requires more sophisticated and costly hardware. To guide future aerospace deployments, we must understand how well these standards relatively perform in analog environments under expected operating conditions. Specifically, we are interested in evaluating goodput -- application level throughput -- in a representative crewed environment

  7. Tendências da desigualdade salarial para coortes de mulheres brancas e negras no Brasil

    Directory of Open Access Journals (Sweden)

    Ana Maria Hermeto Camilo de Oliveira

    2006-06-01

    Full Text Available É feita uma análise das tendências da desigualdade salarial da força de trabalho feminina no Brasil, segundo a raça, durante as décadas de 1980 e 1990. Crescentes retornos de qualificação e crescente demanda por trabalho qualificado resultam em uma divergência do crescimento salarial entre os trabalhadores com alta e baixa qualificação. Este crescente hiato resulta em um aumento da desigualdade salarial por raça. Com o propósito de interpretar as tendências, são examinadas diferenças por raça nos padrões de casamento, fecundidade, arranjos domiciliares, níveis educacionais, participação na força de trabalho, níveis de qualificação, alocação ocupacional e salários, distinguindo entre medidas de período e coorte. São usados dados provenientes das PNADs 1987-1999 para analisar a importância de mudanças inter e intracoortes para mulheres brancas e negras. Funções salariais são estimadas a partir dos dados agregados da série temporal de cross sections, usando mínimos quadrados ordinários e regressões quantílicas.We analyze trends of wage inequality of the Brazilian female labor force, by race, during the 1980s and 1990s. Increasing returns to skills and increasing demand for skilled labor result in a divergence of wages growth between high and low skilled workers. This increasing gap results in an increase of wage inequality by race. In order to interpret trends, we take into account race differences in marriage patterns, fertility, household arrangements, educational levels, labor market participation, skill levels, occupational location and earnings, distinguishing between period and cohort measures. We use 1987-1999 Brazilian Household Sample Surveys data to examine the importance of within- and between-cohort changes for black and white women. Earnings functions are estimated from the pooled time-series of these cross-section data, using OLS and quantile regressions.

  8. Networks of conforming or nonconforming individuals tend to reach satisfactory decisions.

    Science.gov (United States)

    Ramazi, Pouria; Riehl, James; Cao, Ming

    2016-11-15

    Binary decisions of agents coupled in networks can often be classified into two types: "coordination," where an agent takes an action if enough neighbors are using that action, as in the spread of social norms, innovations, and viral epidemics, and "anticoordination," where too many neighbors taking a particular action causes an agent to take the opposite action, as in traffic congestion, crowd dispersion, and division of labor. Both of these cases can be modeled using linear-threshold-based dynamics, and a fundamental question is whether the individuals in such networks are likely to reach decisions with which they are satisfied. We show that, in the coordination case, and perhaps more surprisingly, also in the anticoordination case, the agents will indeed always tend to reach satisfactory decisions, that is, the network will almost surely reach an equilibrium state. This holds for every network topology and every distribution of thresholds, for both asynchronous and partially synchronous decision-making updates. These results reveal that irregular network topology, population heterogeneity, and partial synchrony are not sufficient to cause cycles or nonconvergence in linear-threshold dynamics; rather, other factors such as imitation or the coexistence of coordinating and anticoordinating agents must play a role.

  9. Mechanized systems for early stand tending in central and eastern Canada

    Energy Technology Data Exchange (ETDEWEB)

    Ryans, M.; St-Amour, M. [Forest Engineering Research Inst. of Canada, Pointe Claire, PQ (Canada)

    1996-12-31

    Machines are currently being used for early stand tending in central and eastern Canada, but account for only 1 to 2% of the annual total for mechanical treatments (including manual and motor-manual operations). Selective and non-selective systems are used, depending on the application and stand conditions. Plantation cleaning operations and precommercial thinning (spacing) of naturally regenerated and seeded stands have been mechanized. Selective methods, primarily for plantation cleaning, use equipment with specialized prime movers, booms and controls, and cutting heads. This paper describes the Canadian experience to date based on FERIC`s studies of successful and unsuccessful operations, and lists the key features of a machine suitable for use in selective treatments. Strip precommercial thinning is used in denser natural stands, but limited improvements in crop-tree growth occur unless a motor-manual follow-up releases crop trees in the leave strips. Most off-the-shelf brushcutting equipment is not optimal for this application, primarily because it is too wide to meet local spacing prescriptions. Some applications such as the spacing of older natural stands have proven difficult to mechanize. Technical, biological, operational , regulatory, economic and social constraints prevent wider use of mechanized systems. Nonetheless, some machines are in operational use, and mechanized plantation cleaning is tested in some regions as an alternative to herbicides. 11 refs, 2 figs, 1 tab

  10. Gas in the rectum tends to reduce during radical external beam radiotherapy for localised prostate cancer

    International Nuclear Information System (INIS)

    Nakamura, Naoki; Mizuno, Norifumo; Endo, Haruna; Ogita, Mami; Kawamori, Jiro; Sekigucho, Kenji; Hatanaka, Shogo; Takahashi, Osamu; Tamaki, Seiichi; Shikama, Naoto

    2014-01-01

    This study aims to clarify the time-course of gas accumulation in the rectum during treatment as guidance for the management of rectal volumes. We reviewed 2042 sets (35.2 sets per patient) of anteroposterior and right–left mega voltage (MV) images obtained for daily set-up from 58 patients who underwent radical external beam radiotherapy for localised prostate cancer. The patients were instructed to take magnesium oxide tablets during radiotherapy. They were also encouraged to avoid foods that might cause intestinal gas during radiotherapy. Gas accumulation in the rectum was graded into three classes by the same radiation oncologist. If no gas was seen in the rectum, it was classified as grade 0. A small amount of gas was classified as grade 1, whereas a marked amount of gas that required removal was classified as grade 2. Of the 2042 sets of MV images, grades 1 and 2 gas accumulation were seen in 332 (16%) and 156 (8%), respectively. By the trend test, gas accumulation significantly decreased towards the end of treatment (P=0.02 for grade 1 or 2 and P=0.02 for grade 2). On multivariate analysis, we did not identify any significant independent predictors for either baseline gas accumulation or gas reduction. Gas accumulation tended to decrease until the end of treatment. This tendency should be reconfirmed by other institutions.

  11. Keeping it simple: flowering plants tend to retain, and revert to, simple leaves.

    Science.gov (United States)

    Geeta, R; Dávalos, Liliana M; Levy, André; Bohs, Lynn; Lavin, Mathew; Mummenhoff, Klaus; Sinha, Neelima; Wojciechowski, Martin F

    2012-01-01

    • A wide range of factors (developmental, physiological, ecological) with unpredictable interactions control variation in leaf form. Here, we examined the distribution of leaf morphologies (simple and complex forms) across angiosperms in a phylogenetic context to detect patterns in the directions of changes in leaf shape. • Seven datasets (diverse angiosperms and six nested clades, Sapindales, Apiales, Papaveraceae, Fabaceae, Lepidium, Solanum) were analysed using maximum likelihood and parsimony methods to estimate asymmetries in rates of change among character states. • Simple leaves are most frequent among angiosperm lineages today, were inferred to be ancestral in angiosperms and tended to be retained in evolution (stasis). Complex leaves slowly originated ('gains') and quickly reverted to simple leaves ('losses') multiple times, with a significantly greater rate of losses than gains. Lobed leaves may be a labile intermediate step between different forms. The nested clades showed mixed trends; Solanum, like the angiosperms in general, had higher rates of losses than gains, but the other clades had higher rates of gains than losses. • The angiosperm-wide pattern could be taken as a null model to test leaf evolution patterns in particular clades, in which patterns of variation suggest clade-specific processes that have yet to be investigated fully. © 2011 The Authors. New Phytologist © 2011 New Phytologist Trust.

  12. A transição nutricional no Brasil: tendências regionais e temporais

    Directory of Open Access Journals (Sweden)

    Batista Filho Malaquias

    2003-01-01

    Full Text Available Tendo como principal fonte de informações três estudos transversais realizados nas décadas de 70, 80 e 90, faz-se uma análise da transição nutricional do Brasil, referenciada no rápido declínio da prevalência de desnutrição em crianças e elevação, num ritmo mais acelerado, da prevalência de sobrepeso/obesidade em adultos. A correção dos déficits de estatura foi de 72% em crianças urbanas e de 54,4% no meio rural, enquanto a ocorrência de obesidade duplicou ou triplicou em homens e mulheres adultos nos extremos da série temporal analisada. Com exceção do Nordeste rural, a prevalência de desnutrição em mulheres adultas declinou para taxas aceitáveis (em torno de 5% a partir de 1989. Inversamente, as anemias continuam com prevalências elevadas e indicações de tendências epidêmicas. Descreve-se a evolução do estado nutricional da população brasileira segundo macrorregiões e distribuição social, analisando-se os prováveis fatores das mudanças ocorridas.

  13. Tendências em séries anuais de precipitação e temperaturas no Brasil

    Directory of Open Access Journals (Sweden)

    Júlio César Penereiro

    Full Text Available RESUMO Nas últimas décadas, pesquisadores científicos e acadêmicos em todo o mundo têm se preocupado com a avaliação das tendências dos climas regional e global. A avaliação das alterações no clima é uma ferramenta para o planejamento da sociedade, pois permite considerar as possíveis consequências do aumento das temperaturas do ar e de mudanças no regime de precipitação que foram observadas ao redor do mundo. Sob a hipótese da presença de alterações climáticas no Brasil, o objetivo do presente estudo foi identificar a existência de tendências climáticas em 243 séries anuais de temperaturas máxima, mínima e média do ar (T-Máx., T-Mín. e T-Méd. e precipitação pluviométrica (Prec. em cidades do Brasil. Foram empregados os testes estatísticos de Mann-Kendall (M-K. e Pettitt (Pett. para avaliação de tendências significativas. Para a visualização espacial das tendências observadas, foram elaborados mapas. Os resultados estatísticos mostram que, de todas as cidades estudadas, foram observadas tendências positivas na T-máx. em 35% das séries, negativas em 1% e ausência de tendência em 64%. Para a T-Mín., foram observadas tendências positivas em 30% dos casos, negativas em 8% e ausência de tendência em 63%. Na T-Méd., tendência positiva foi detectada em 35% das cidades analisadas, negativa em 3% e ausência de tendência em 62%. Por fim, na Prec., tendência positiva em 6% dos casos, negativa em 4% e ausência de tendência em 91%. As tendências observadas no presente estudo estão possivelmente relacionadas às atividades antrópicas em cada localidade, como o expansionismo urbano, o desenvolvimento industrial e o adensamento populacional.

  14. Retrospectiva e tendência da alfacicultura brasileira Retrospective and trends of Brazilian lettuce crop

    Directory of Open Access Journals (Sweden)

    Fernando Cesar Sala

    2012-06-01

    Full Text Available A alface é considerada a principal hortaliça folhosa no Brasil. Nas ultimas décadas, houve muitas mudanças quanto aos tipos varietais predominantes no país bem como para a preferência do uso de semente peletizada. O domínio do cultivo da alface lisa foi até a década de 90 com as cultivares do tipo 'manteiga' e 'Regina'. Posteriormente, houve uma mudança para o tipo crespa e que, atualmente, corresponde ao principal segmento cultivado no Brasil. A ausência de formação de cabeça aliada à presença de folhas flabeladas conferiram a esse tipo de alface uma melhor adaptação no cultivo de verão com altas temperaturas e índices de pluviosidade. A preferência brasileira pela alface crespa é um fato único na alfacicultura mundial. A alface americana vem apresentando maiores índices de crescimento e aceitação pelo mercado consumidor. Apesar de apresentar formação de cabeça e que tem limitado seu cultivo no verão, na ausência de cultivo protegido, suas folhas mais espessas têm conferido melhor sabor, crocância e durabilidade pós-colheita na alface americana. Alface com folha espessa é mandatória para o mercado de processamento que apresenta alta tendência de crescimento. Considerações sobre o melhoramento genético para contribuir, pelo menos em parte, com essa situação são discutidas com o surgimento de novos tipos varietais tropicalizados, com a tendência de segmentação de mercado e da necessidade de uma cadeia pós-colheita mais eficiente.Lettuce is considered the main leafy vegetable crop in Brazil. In recent decades, many changes occurred towards the varietal types as well as in the preference for pelleted seeds. Until mid 90 decade, the dominant varieties of looseleaf lettuce were the type 'White Boston' and 'Regina'. Later, there was a change toward the Grand Rapids type which represents the main varietal segment grown in Brazil. The non-head Grand Rapids type with its earliness performed better adaptation

  15. Abstinent Heroin Addicts Tend to Take Risks: ERP and Source Localization

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    Qinglin Zhao

    2017-12-01

    Full Text Available Abnormal decision making is a behavioral characteristic of drug addiction. Indeed, drug addicts prefer immediate rewards at the expense of future interests. Assessing the neurocognitive basis of decision-making related to drug dependence, combining event-related potential (ERP analysis and source localization techniques, may provide new insights into understanding decision-making deficits in drug addicts and further guide withdrawal treatment. In this study, EEG was performed in 20 abstinent heroin addicts (AHAs and 20 age-, education- and gender-matched healthy controls (HCs while they participated in a simple two-choice gambling task (99 vs. 9. Our behavioral results showed that AHAs tend to select higher-risk choices compared with HCs (i.e., more “99” choices than “9”. ERP results showed that right hemisphere preponderance of stimulus-preceding negativity was disrupted in AHAs, but not in HCs. Feedback-related negativity of difference wave was higher in AHAs than HCs, with the P300 amplitude associated with risk magnitude and valence. Using source localization that allows identification of abnormal brain activity in consequential cognitive stages, including the reward expectation and outcome evaluation stages, we found abnormalities in both behavioral and neural responses on gambling in AHAs. Taken together, our findings suggest AHAs have risk-prone tendency and dysfunction in adaptive decision making, since they continue to choose risky options even after accruing considerable negative scores, and fail to shift to a safer strategy to avoid risk. Such abnormal decision-making bias to risk and immediate reward seeking may be accompanied by abnormal reward expectation and evaluation in AHAs, which explains their high risk-seeking and impulsivity.

  16. Orlando, ou a tendência social da androginia Orlando. The social tendency of androginy

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    Nízia Maria Alvarenga

    1997-10-01

    Full Text Available Este artigo analisa o filme Orlando por ser expressão de uma das tendências que vêm despontando no processo atual de mudanças sociais no conjunto das sociedades capitalistas ocidentais. A dimensão simbólica destas sociedades abrange representações tais como racionalidade, objetividade, pragmatismo, impessoalidade, utilitarismo, disciplina e neutralidade afetiva, que constituem o cerne do sistema de valores sociais predominantes. Uma alteração desta dimensão significa uma revolução em seu modo de ser social. Orlando sugere uma reconciliação entre razão, sensibilidade, emoções, sentimentos e fantasia, abrindo espaço para uma sociedade andrógina, presidida pelo princípio erótico. A dinâmica produtivista do capitalismo é substituída por uma forma de sociabilidade marcada pela amorosidade e o desfrute da vida.This article analyzes the film Orlando because it is representative of one of the trends which are emerging in the actual process of social changes occurring in the west capitalist societies. The symbolic dimension of these societies comprehends representations such as rationality, objectivity, pragmatism, unpersonalty, utilitarianism, discipline and affective neutrality which constitute the nucleous of the system of predominant social values. A change of this dimension signifies a revolution on the way of social being. Orlando suggests a reconciliation between reason, sensibility, emotions, feelings and phantasy, opening place for a androgynous society presided by the erotic principle. The productive dynamic of the capitalism is substituted by a form of sociability marked by affection and enjoyment of living.

  17. Tendências no processamento de frangos de corte: uso racional da água

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    Ricardo Lacava Bailone

    Full Text Available RESUMO Atualmente o uso racional da água vem sendo tema de discussão perante órgãos governamentais e não governamentais ao redor do mundo. Seguindo essa tendência, leis cada vez mais severas devem ser implantadas em relação ao uso desse bem natural. Em um frigorífico de frango, o uso da água ocorre de forma generalizada ao longo de todo o processo industrial. Nesse contexto, o atual estudo teve o objetivo de comparar o consumo de água em um frigorífico brasileiro de frangos de corte (grande porte com modelos já propostos e utilizados em outros países com o intuito de identificar soluções para mitigar perdas provenientes de sua má gestão. Concluiu-se que alterações em alguns pontos-chave do processamento possibilitariam à indústria o uso mais sustentável da água, como substituição da eletronarcose por insensibilização a gás, diminuição da dimensão do tanque de escaldagem ou mudança no processo, substituição do pré-resfriamento por imersão em água por pré-resfriamento a ar, redução da renovação de água nos tanques resfriadores, alterações no sistema de geração do frio em ambientes climatizados, assim como o reúso total ou parcial da água.

  18. Tendências no processamento de frangos de corte: uso racional da água

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    Ricardo Lacava Bailone

    2016-10-01

    Full Text Available RESUMO Atualmente o uso racional da água vem sendo tema de discussão perante órgãos governamentais e não governamentais ao redor do mundo. Seguindo essa tendência, leis cada vez mais severas devem ser implantadas em relação ao uso desse bem natural. Em um frigorífico de frango, o uso da água ocorre de forma generalizada ao longo de todo o processo industrial. Nesse contexto, o atual estudo teve o objetivo de comparar o consumo de água em um frigorífico brasileiro de frangos de corte (grande porte com modelos já propostos e utilizados em outros países com o intuito de identificar soluções para mitigar perdas provenientes de sua má gestão. Concluiu-se que alterações em alguns pontos-chave do processamento possibilitariam à indústria o uso mais sustentável da água, como substituição da eletronarcose por insensibilização a gás, diminuição da dimensão do tanque de escaldagem ou mudança no processo, substituição do pré-resfriamento por imersão em água por pré-resfriamento a ar, redução da renovação de água nos tanques resfriadores, alterações no sistema de geração do frio em ambientes climatizados, assim como o reúso total ou parcial da água.

  19. Considerações sobre a tendência da tuberculose no Brasil

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    Dina Czeresnia Costa

    1985-09-01

    Full Text Available Este trabalho analisa os vários aspectos que influenciam no padrão da mortalidade e morbidade da tuberculose: a variação nas condições de vida, os efeitos da quimioterapia e a dinâmica de transmissão da doença. Caracteriza os indicadores utilizados na medida da tuberculose que são construídos a partir de inquéritos de prevalência e dos dados de notificação. Os principais indicadores são: risco de infecção; mortalidade; coeficiente de incidência de meningite tuberculosa; coeficientes de incidência de casos de tuberculose, especialmente os pulmonares bacilíferos, etc. O trabalho analisa dados recentes de incidência de casos pulmonares bacilíferos nos estados do Pará e Rio Grande do Sul e mortalidade por tuberculose nas capitais do Pará, Rio Grande do Sul, Pernambuco e Rio de Janeiro, que revelam uma tendência à queda, ainda que em ritmo diferenciado. Discute-se a maneira que a crise econômica atual do país repercutiria no número de casos e mortes pela doença.This paper analises the various factors which affect the rate of mortality and illness from tuberculosis i.e. the variation in the quality of life of the people affected, the effects o f chemotherapy and the dynamics of the transmission of the disease. It describes the epidemiological indices used to measure the spread of tuberculosis. These indices are built up from inquiries of prevalence of the disease and the number of notified cases. The main indices are: the risk of infection, mortality, the coefficient of the incidence of tubercular meningitis, the coefficient of the incidence of cases of tuberculosis, especially smear positives, etc. The paper also analises recent data of incidence of cases of smear positives in the states of Pará and Rio Grande do Sul and the mortality rate from tuberculosis in the state capitals of Pará, Rio Grande do Sul, Pernambuco and Rio de Janeiro, which reveal a downward trend, thought at different rates. The nature of how the

  20. Clever sillies: why high IQ people tend to be deficient in common sense.

    Science.gov (United States)

    Charlton, Bruce G

    2009-12-01

    In previous editorials I have written about the absent-minded and socially-inept 'nutty professor' stereotype in science, and the phenomenon of 'psychological neoteny' whereby intelligent modern people (including scientists) decline to grow-up and instead remain in a state of perpetual novelty-seeking adolescence. These can be seen as specific examples of the general phenomenon of 'clever sillies' whereby intelligent people with high levels of technical ability are seen (by the majority of the rest of the population) as having foolish ideas and behaviours outside the realm of their professional expertise. In short, it has often been observed that high IQ types are lacking in 'common sense'--and especially when it comes to dealing with other human beings. General intelligence is not just a cognitive ability; it is also a cognitive disposition. So, the greater cognitive abilities of higher IQ tend also to be accompanied by a distinctive high IQ personality type including the trait of 'Openness to experience', 'enlightened' or progressive left-wing political values, and atheism. Drawing on the ideas of Kanazawa, my suggested explanation for this association between intelligence and personality is that an increasing relative level of IQ brings with it a tendency differentially to over-use general intelligence in problem-solving, and to over-ride those instinctive and spontaneous forms of evolved behaviour which could be termed common sense. Preferential use of abstract analysis is often useful when dealing with the many evolutionary novelties to be found in modernizing societies; but is not usually useful for dealing with social and psychological problems for which humans have evolved 'domain-specific' adaptive behaviours. And since evolved common sense usually produces the right answers in the social domain; this implies that, when it comes to solving social problems, the most intelligent people are more likely than those of average intelligence to have novel but

  1. FECAL EXCRETION OF Salmonella Enteritidis IN BROILER LINES ROSS AND ISA LABEL EXCREÇÃO FECAL de Salmonella Enteritidis EM DUAS LINHAGENS DE FRANGOS DE CORTE

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    Adson Santa Cruz Oliveira

    2007-12-01

    Full Text Available

    The invasive capacity and persistence of this pathogen, crop and ceca in apparently healthy birds of two broiler lines raised without growth promoter antibiotics in ration and originated from eggs inoculated eggshell and in allantoidal cavity with Salmonella Enteritidis. Histological and bacteriological exams from cecal and crop were performed with one, seven, 14 and 21 days of age after hatch in broilers of fast and slow growing rate. Bacterio-logical exams were performed fecal excretion with one, eigth, 22 and 35 days. The Salmonella Enteritidis invaded and colonizated the gastrointestinal tract of the two lines tested, but the the infection reduced with age, and was more persistant in Ross broilers. The results were different for two lines. The pathogen was excreted from just one chick of ISA Label at 22 days of age and four Ross chicks until 35 days of age. In order, Salmonella was detected in 87.5% (14/16 and 38,1% (5/16 of ceca; in 81.2% (13/16 and 12.5% (2/16 of crops; in fast and slow growing rate lines, respectively. In apparent healthy organs, excepted the crop, an inflammatory process with predominance of macrophage and lymphocytes. The slow growing rate line was effective to eliminate bacteria in the organism.

    Key-words: Ceca, crop, fecal excretion, inflammation.

    Avaliaram-se, neste estudo, a capacidade inva-siva, a persistência e a freqüência de excreção fecal da Salmonella Enteritidis em aves aparentemente saudáveis de duas linhagens de frango de corte, criadas sem antibióticos promotores de crescimento na ração e oriundas de ovos inoculados na casca ou na cavidade alantóide com Salmonella Enteritidis fagotipo 4. Realizaram-se exames bacteriológicos das excretas com um, oito, 22 e 35 dias, e histológicos e bacteriológicos do inglúvio e ceco, com um, sete, quatorze e 21 dias pós-eclosão em frangos de crescimento rápido e lento. Salmonella

  2. Safety and immunogenicity of a malaria vaccine, Plasmodium falciparum AMA-1/MSP-1 chimeric protein formulated in montanide ISA 720 in healthy adults.

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    Jinhong Hu

    Full Text Available BACKGROUND: The P. falciparum chimeric protein 2.9 (PfCP-2.9 consisting of the sequences of MSP1-19 and AMA-1 (III is a malaria vaccine candidate that was found to induce inhibitory antibodies in rabbits and monkeys. This was a phase I randomized, single-blind, placebo-controlled, dose-escalation study to evaluate the safety and immunogenicity of the PfCP-2.9 formulated with a novel adjuvant Montanide ISA720. Fifty-two subjects were randomly assigned to 4 dose groups of 10 participants, each receiving the test vaccine of 20, 50, 100, or 200 microg respectively, and 1 placebo group of 12 participants receiving the adjuvant only. METHODS AND FINDINGS: The vaccine formulation was shown to be safe and well-tolerated, and none of the participants withdrew. The total incidence of local adverse events (AEs was 75%, distributed among 58% of the placebo group and 80% of those vaccinated. Among the vaccinated, 65% had events that were mild and 15% experienced moderate AEs. Almost all systemic adverse reactions observed in this study were graded as mild and required no therapy. The participants receiving the test vaccine developed detectable antibody responses which were boosted by the repeated vaccinations. Sixty percent of the vaccinated participants had high ELISA titers (>1:10,000 of antigen-specific antibodies which could also recognize native parasite proteins in an immunofluorescence assay (IFA. CONCLUSION: This study is the first clinical trial for this candidate and builds on previous investigations supporting PfCP-2.9/ISA720 as a promising blood-stage malaria vaccine. Results demonstrate safety, tolerability (particularly at the lower doses tested and immunogenicity of the formulation. Further clinical development is ongoing to explore optimizing the dose and schedule of the formulation to decrease reactogenicity without compromising immunogenicity. TRIAL REGISTRATION: Chinese State Food and Drug Administration (SFDA 2002SL0046; Controlled

  3. Vaccination with NY-ESO-1 overlapping peptides mixed with Picibanil OK-432 and montanide ISA-51 in patients with cancers expressing the NY-ESO-1 antigen.

    Science.gov (United States)

    Wada, Hisashi; Isobe, Midori; Kakimi, Kazuhiro; Mizote, Yu; Eikawa, Shingo; Sato, Eiichi; Takigawa, Nagio; Kiura, Katsuyuki; Tsuji, Kazuhide; Iwatsuki, Keiji; Yamasaki, Makoto; Miyata, Hiroshi; Matsushita, Hirokazu; Udono, Heiichiro; Seto, Yasuyuki; Yamada, Kazuhiro; Nishikawa, Hiroyoshi; Pan, Linda; Venhaus, Ralph; Oka, Mikio; Doki, Yuichiro; Nakayama, Eiichi

    2014-01-01

    We conducted a clinical trial of an NY-ESO-1 cancer vaccine using 4 synthetic overlapping long peptides (OLP; peptides #1, 79-108; #2, 100-129; #3, 121-150; and #4, 142-173) that include a highly immunogenic region of the NY-ESO-1 molecule. Nine patients were immunized with 0.25 mg each of three 30-mer and a 32-mer long NY-ESO-1 OLP mixed with 0.2 KE Picibanil OK-432 and 1.25 mL Montanide ISA-51. The primary endpoints of this study were safety and NY-ESO-1 immune responses. Five to 18 injections of the NY-ESO-1 OLP vaccine were well tolerated. Vaccine-related adverse events observed were fever and injection site reaction (grade 1 and 2). Two patients showed stable disease after vaccination. An NY-ESO-1-specific humoral immune response was observed in all patients and an antibody against peptide #3 (121-150) was detected firstly and strongly after vaccination. NY-ESO-1 CD4 and CD8 T-cell responses were elicited in these patients and their epitopes were identified. Using a multifunctional cytokine assay, the number of single or double cytokine-producing cells was increased in NY-ESO-1-specific CD4 and CD8 T cells after vaccination. Multiple cytokine-producing cells were observed in PD-1 (-) and PD-1 (+) CD4 T cells. In conclusion, our study indicated that the NY-ESO-1 OLP vaccine mixed with Picibanil OK-432 and Montanide ISA-51 was well tolerated and elicited NY-ESO-1-specific humoral and CD4 and CD8 T-cell responses in immunized patients.

  4. Determination of the Morphology of the Starch Granules and the Optimum Internal Cooking Temperature of Four Andean Crops: Oca (Oxalis tuberosa Molina, Olluco (Ullucus tuberosus Loz, Isaño (Tropaeolum tuberosum Ruiz

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    Bellido-Valencia Omar

    2017-12-01

    Full Text Available Andean grains (i.e. quinoa, amaranth have been increasingly studied in recent times, mainly due to the increase in international consumption. However, Andean tubers other than potatoes have not been so widespread and are mainly studied for their starch, previously extracted. This work studied the morphology of native starch in four of these crops (oca, olluco, isaño and aracacha, during cooking and the evolution of their internal temperature in relation to sensory acceptability. Using scanning electron microscopy, it was determined that the size of crude starch granules was between 9 μm to 38.2 μm for oca, 4.48 to 24.9 μm for olluco, 4.45 to 22.9 μm for isaño, and 5.36 to 23.8 μm for arracacha. Sensorially, it was determined that the optimum cooking temperature for arracacha was 89.1°C, 90.9°C for oca, 91°C for isaño, and 91.4 °C for olluco. All samples had optimal cooking times shorter than potato, with the isaño having the best heat transfer.

  5. Tendências na assistência hospitalar Trends in hospital care

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    Gonzalo Vecina Neto

    2007-08-01

    Full Text Available Este artigo analisa as tendências observadas na assistência hospitalar brasileira, no que diz respeito ao cenário, situação atual, desafios e ao que necessita ser feito, tendo em vista os itens anteriores. As variáveis com as quais se trabalhou o cenário geral foram a demografia, o perfil epidemiológico, os recursos humanos, a tecnologia, a medicalização, os custos, a revisão do papel do cidadão, a legislação, a eqüidade, o hospitalocentrismo e a regionalização, o fracionamento do cuidado e a oferta de leitos. O cenário nacional foi estudado mediante o modelo empregado na assistência médica supletiva, o financiamento e a cadeia de produção na área de serviços de saúde. A situação atual apresenta os modelos de avaliação externa, a terceirização, o relacionamento público-privado, a desospitalização e o financiamento. Os desafios a serem enfrentados analisam a necessidade de se olhar o longo prazo, a busca por novos modelos jurídicos para o "negócio", o uso da informação e a informatização, o controle de custos e a necessidade do aumento da eficiência e do cumprimento dos ditames legais, de garantia de acesso e de integralidade na assistência, a incorporação da prevenção primária ao processo de atenção, a integração entre os setores público e privado e a incorporação do médico na solução dos problemas.This paper analyses trends in the delivery of hospital services in Brazil, considering the setting, the current situation and its challenges, examining what still remains to be done. The variables studied for the analysis of the setting are: demography, epidemiological profile, human resources, technology, medicalization, costs, review of the role of the citizen, legislation, equity, hospital-centricity and regionalization, care fractioning and bed availability. The Brazilian setting was studied through the supplementary healthcare model, financing and the healthcare area production chain. The

  6. The links between implementing ISA 540 and mitigating the practice of smoothing reported net earnings using write-offs of accounts receivable and inventory by reporting entities in Poland

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    Andrzej Krystian Piosik

    2016-06-01

    Full Text Available The paper addresses the question of the links between implementing ISA 540 and mitigating the practice of smoothing reported net earnings using write-offs of accounts receivable and inventory by reporting entities in Poland. The research question stems from the previous analysis carried out by the author in which evidence was provided that reporting entities in Poland in the period 2000–2010 effectively used write-offs of accounts receivable and inventory in order to mitigate fluctuations of reported net earnings. This paper provides evidence that before implementing ISA 540 reporting entities used write-offs of receivables and inventory for income smoothing in effective manner, however in the period after implementing the standard (2009–2014 no link was observed between the write-offs and reduced fluctuations of reported net earnings. The research has been carried out using Wilcoxon signed-rank test used to check equality of medians of mean deviations of net earnings before write-offs of receivables and inventory and mean deviations of net earnings after write-offs. For the period before implementing ISA 540 there are grounds to reject the hypothesis of equality of medians of mean deviations of net earnings, however in the post-adoption period there is no justification to reject the hypothesis of equality of medians. The research provides evidence of positive impact of ISA 540 mitigating the processes of accounting earnings management. The indicated regularity does not apply to banks, because within this group of companies we have not observed the use of write-offs of loan receivables in order to reduce the variability of net earnings before implementing ISA 540 and in the period following the implementation of the standard.

  7. Estudio comparativo de cirugía percutánea del tendón de Aquiles asistida ecográficamente con la cirugía abierta convencional en roturas de tendón de Aquiles

    OpenAIRE

    Rubio Lorenzo, Mónica

    2017-01-01

    RESUMEN:El tendón de Aquiles es el tendón que con más frecuencia se rompe del cuerpo humano. Generalmente ocurre en la etapa laboral y deportiva de la vida, y conllevan complicaciones postquirúrgicas, tiempo de incapacidad laboral y restringen la calidad de vida de los pacientes, limitando su actividad deportiva y cotidiana posterior. Desarrollamos una técnica percutánea ecoguiada, y lo comparamos con la técnica convencional abierta. Encontramos que: existen diferencias significativa...

  8. Large for Gestational Age Newborns from Mothers Without Diabetes Mellitus Tend to Become Tall and Lean Toddlers.

    Science.gov (United States)

    de Zegher, Francis; Pérez-Cruz, Miriam; Sebastiani, Giorgia; Díaz, Marta; López-Bermejo, Abel; Ibáñez, Lourdes

    2016-11-01

    A longitudinal study with dual x-ray absorptiometry disclosed that infants born large for gestational age from mothers without diabetes mellitus and without excessive gestational weight gain tend to be long with increased adipose tissue as newborns and tall and lean as toddlers. Copyright © 2016 Elsevier Inc. All rights reserved.

  9. Effect of genotype and transport on tonic immobility and heterophil/lymphocyte ratio in two local Italian breeds and Isa Brown hens kept under free-range conditions

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    Michele De Marco

    2013-10-01

    Full Text Available This study was undertaken to investigate the effect of transport and genotype on the welfare and fear response of laying hens through a comparison of three breeds reared in free-range conditions: a commercial strain, the Isa Brown (IBh, and two local chicken breeds, the Bionda Piemontese (BPh and the Bianca di Saluzzo (BSh. After a journey of 67 km (75 min from the farmhouse of origin to the experimental station, ninety hens, divided according to breed, were free-range reared for two months. Body weight (BW, tonic immobility (TI, red and white blood cells, heterophil to lymphocyte (H/L ratio and α1-acid glycoprotein (AGP were assessed at four different sampling times: at the farmhouse of origin (T1, at 1 day (T2, 15 days (T3 and at 2 months (T4 after arrival at the experimental station. No statistical differences were found between the four sampling times for BW, total red and white blood parameters. cells or for AGP. An increase in the H/L ratio (P<0.05 was recorded at time T2 for IBh and BSh, compared to BPh (P<0.05. TI was significantly higher (P<0.05 for the local breeds, BPh and BSh, than for the commercial strain IBh. The results of this study suggest that genetic and adaptive differences can affect both, physiological and ethological parameters.

  10. Utilisation of ISA Reverse Genetics and Large-Scale Random Codon Re-Encoding to Produce Attenuated Strains of Tick-Borne Encephalitis Virus within Days.

    Science.gov (United States)

    de Fabritus, Lauriane; Nougairède, Antoine; Aubry, Fabien; Gould, Ernest A; de Lamballerie, Xavier

    2016-01-01

    Large-scale codon re-encoding is a new method of attenuating RNA viruses. However, the use of infectious clones to generate attenuated viruses has inherent technical problems. We previously developed a bacterium-free reverse genetics protocol, designated ISA, and now combined it with large-scale random codon-re-encoding method to produce attenuated tick-borne encephalitis virus (TBEV), a pathogenic flavivirus which causes febrile illness and encephalitis in humans. We produced wild-type (WT) and two re-encoded TBEVs, containing 273 or 273+284 synonymous mutations in the NS5 and NS5+NS3 coding regions respectively. Both re-encoded viruses were attenuated when compared with WT virus using a laboratory mouse model and the relative level of attenuation increased with the degree of re-encoding. Moreover, all infected animals produced neutralizing antibodies. This novel, rapid and efficient approach to engineering attenuated viruses could potentially expedite the development of safe and effective new-generation live attenuated vaccines.

  11. Arquitectura flexible basada en ISA 88 para el diseño del diagrama de control de ejecución en aplicaciones distribuidas usando IEC 61499

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    Fabricio Chicaiza

    2018-03-01

    Full Text Available En la actualidad los sistemas de automatización industrial deben optimizar las técnicas de control y comunicación de sus procesos, para introducir conceptos dados por la Industria 4.0. Para lograr esto se necesita de la introducción de nuevas normas de automatización para obtener sistemas de fabricación ágiles e inteligentes, es por esto que la norma IEC 61499 es considerada como la opción principal. Industria 4.0 en unión con IEC 61499 permitirá la integración de sistemas de adquisición de datos tradicionales y novedosos sistemas de procesamiento inteligente de datos, con el objetivo de extraer información y mejorar el rendimiento general del sistema productivo. El presente trabajo establece un enfoque de arquitectura flexible para el diseño de los Diagramas de Control de Ejecución de los Bloques de Función basado en la norma ISA 88 aplicado a un proceso industrial, lo que permitirá implementar el control industrial bajo IEC 61499 de manera eficiente y rápida permitiendo un diseño se software basado en componentes con independencia de la plataforma hardware usada.

  12. Tendências na incidência e mortalidade por acidentes de trabalho no Brasil, 1998 a 2008

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    Flávia Souza e Silva de Almeida

    2014-09-01

    Full Text Available O objetivo do estudo foi avaliar as tendências na incidência e mortalidade por acidentes de trabalho no Brasil, de 1998 a 2008. Trata-se de estudo ecológico de séries temporais, que incluiu, para a análise, os acidentes de trabalho registrados nas estatísticas oficiais do Governo Federal. Foram calculadas as variações percentuais anuais (APC nas taxas de incidência e de mortalidade, através da modelagem pelo método Joinpoint, usando o ano calendário como variável regressora. Observou-se tendência significativa de decréscimo na taxa de incidência de acidentes de trabalho, o mesmo ocorrendo para os acidentes de trabalho típicos. Para ambos, o número de casos aumentou nesse período. O número de casos de acidentes de trabalho de trajeto e sua incidência mostraram tendência significativa de aumento. O número de óbitos e a taxa de mortalidade registraram tendência de decréscimo. São discutidos como fatores contribuintes para o declínio das taxas de incidência de acidentes de trabalho e de mortalidade por esta causa: melhoria das condições de trabalho, maior crescimento do setor de serviços do que do setor industrial, subnotificação dos acidentes de trabalho e terceirização dos serviços. O aumento dos acidentes de trabalho de trajeto sugere a influência da violência dos centros urbanos.

  13. Análise de tendência do mercado internacional de aglomerado Analysis of international particleboard market tendency

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    Rommel Noce

    2008-04-01

    Full Text Available Neste estudo, analisou-se, pelo método da regressão linear, a tendência do mercado internacional de aglomerado no período de 1990 a 2004. Observou-se tendência de crescimento tanto de produção quanto de exportação, com a ressalva de que o Brasil expande sua produção em ritmo mais acelerado que a produção mundial. Conclui-se que China, Ucrânia e EUA apresentaram maior crescimento, quanto à produção, exportação e importação, entre os mercados tradicionais, respectivamente, e que os mercados não-tradicionais mudaram tendências de crescimento superiores ao grupo dos principais importadores, especialmente o leste europeu.This study analyzed international particleboard market tendency in the period from 1990 to 2004, using the linear regression method. Growth tendency was observed both for production and export, stressing that Brazil's production is expanding in a more accelerated rhythm than the world production. China, Ukraine and USA presented a greater production, export and import growth among the traditional markets, respectively, and the nontraditional markets presented greater growth tendencies, compared to the major import groups, especially East Europe.

  14. Global Derivatives

    DEFF Research Database (Denmark)

    Andersen, Torben Juul

    approaches to dealing in the global business environment." - Sharon Brown-Hruska, Commissioner, Commodity Futures Trading Commission, USA. "This comprehensive survey of modern risk management using derivative securities is a fine demonstration of the practical relevance of modern derivatives theory to risk......" provides comprehensive coverage of different types of derivatives, including exchange traded contracts and over-the-counter instruments as well as real options. There is an equal emphasis on the practical application of derivatives and their actual uses in business transactions and corporate risk...... management situations. Its key features include: derivatives are introduced in a global market perspective; describes major derivative pricing models for practical use, extending these principles to valuation of real options; practical applications of derivative instruments are richly illustrated...

  15. Safety and immunogenicity of a recombinant Plasmodium falciparum AMA1 malaria vaccine adjuvanted with Alhydrogel, Montanide ISA 720 or AS02.

    Directory of Open Access Journals (Sweden)

    Meta Roestenberg

    Full Text Available Plasmodium falciparum Apical Membrane Antigen 1 (PfAMA1 is a candidate vaccine antigen expressed by merozoites and sporozoites. It plays a key role in red blood cell and hepatocyte invasion that can be blocked by antibodies.We assessed the safety and immunogenicity of recombinant PfAMA1 in a dose-escalating, phase Ia trial. PfAMA1 FVO strain, produced in Pichia pastoris, was reconstituted at 10 microg and 50 microg doses with three different adjuvants, Alhydrogel, Montanide ISA720 and AS02 Adjuvant System. Six randomised groups of healthy male volunteers, 8-10 volunteers each, were scheduled to receive three immunisations at 4-week intervals. Safety and immunogenicity data were collected over one year. Transient pain was the predominant injection site reaction (80-100%. Induration occurred in the Montanide 50 microg group, resulting in a sterile abscess in two volunteers. Systemic adverse events occurred mainly in the AS02 groups lasting for 1-2 days. Erythema was observed in 22% of Montanide and 59% of AS02 group volunteers. After the second dose, six volunteers in the AS02 group and one in the Montanide group who reported grade 3 erythema (>50 mm were withdrawn as they met the stopping criteria. All adverse events resolved. There were no vaccine-related serious adverse events. Humoral responses were highest in the AS02 groups. Antibodies showed activity in an in vitro growth inhibition assay up to 80%. Upon stimulation with the vaccine, peripheral mononuclear cells from all groups proliferated and secreted IFNgamma and IL-5 cytokines.All formulations showed distinct reactogenicity profiles. All formulations with PfAMA1 were immunogenic and induced functional antibodies.(Clinicaltrials.gov NCT00730782.

  16. Tendência da prevalência do diabetes melito autorreferido em adultos nas capitais brasileiras, 2006 a 2012

    Directory of Open Access Journals (Sweden)

    Deborah Carvalho Malta

    Full Text Available OBJETIVO: avaliar a tendência da prevalência de diabetes melito autorreferido nas capitais brasileiras, entre 2006 e 2012. MÉTODOS: estudo ecológico com dados da Vigilância de Fatores de Risco e Proteção para Doenças Crônicas por Inquérito Telefônico (Vigitel referentes a adultos (≥18 anos, analisados por meio de regressão linear simples. RESULTADOS: no período estudado, houve tendência de aumento de 5,7% para 7,4% no conjunto da população adulta das capitais (p=0,008, de 4,8% para 6,5% entre homens (p=0,002 e de 6,4% para 8,1% entre mulheres (p=0,039; a elevação entre mulheres ocorreu em 9 capitais - Belém-PA, Belo Horizonte-MG, Curitiba-PR, Macapá-AP, Maceió-AL, Palmas-TO, Recife-PE, Rio Branco-AC e Vitória-ES -; e entre homens, em 6 capitais - Boa Vista-RR, Florianópolis-SC, Fortaleza-CE, Rio Branco-AC, Rio de Janeiro-RJ e São Paulo-SP. CONCLUSÃO: houve aumento da prevalência do diabetes em diversas capitais brasileiras; o monitoramento das tendências e fatores de risco é útil ao planejamento em saúde.

  17. Financial Derivatives

    DEFF Research Database (Denmark)

    Wigan, Duncan

    2013-01-01

    Contemporary derivatives mark the development of capital and constitute a novel form of ownership. By reconfiguring the temporal, spatial and legal character of ownership derivatives present a substantive challenge to the tax collecting state. While fiscal systems are nationally bounded...... and inherently static, capital itself is unprecedentedly mobile, fluid and fungible. As such derivatives raise the specter of ‘financial weapons of mass destruction’....

  18. Financial Derivatives

    OpenAIRE

    Janečková, Alena

    2011-01-01

    1 Abstract/ Financial derivatives The purpose of this thesis is to provide an introduction to financial derivatives which has been, from the legal perspective, described in a not satisfactory manner as quite little literature that can be found about this topic. The main objectives of this thesis are to define the term "financial derivatives" and its particular types and to analyse legal nature of these financial instruments. The last objective is to try to draft future law regulation of finan...

  19. The Iran Sanctions Act (ISA)

    National Research Council Canada - National Science Library

    Katzman, Kenneth

    2009-01-01

    International pressure on Iran to curb its nuclear program is increasing the hesitation of many major foreign firms to invest in Iran's energy sector, hindering Iran's efforts to expand oil production beyond...

  20. eISA Acceptance Form

    Data.gov (United States)

    Department of Homeland Security — This dataset contains the online agreement information needs to share Trade information via a Trade VPN. When submitted, the data is sent in an email to the business...

  1. ISA/92 Canada general program

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    This volume contains the proceedings of a portion of the Instrument Society of America's 1992 General Meeting. Topics covered include: diesel fuels, wastewater treatment, the environment, advancements in measurement and control, improved control systems and construction and design

  2. Tendência secular em estatura: uma revisão da literatura Secular height trend: a literature review

    Directory of Open Access Journals (Sweden)

    Gilberto Kac

    1999-09-01

    Full Text Available Esse trabalho constitui-se em uma revisão de literatura sobre tendência secular em estatura (TSE. Os principais tópicos abordados foram a definição do fenômeno, a utilização de dados históricos de estatura como estratégia alternativa no monitoramento de mudanças econômicas, as principais explicações teóricas sugeridas para a ocorrência do fenômeno, o início da antropometria militar, sua utilização no passado e no presente, e a magnitude da tendência em recrutas e na população infantil. Os principais achados revelaram que a TSE tem sido atribuída, sobretudo, a influências ambientais, em particular, a melhorias nas condições sanitárias, econômicas e sociais. As taxas médias de incremento variaram conforme a idade, o estrato sócio-econômico e o país considerado; portanto, deve-se ter cautela nas comparações interpopulacionais. A Segunda Guerra Mundial reduziu a tendência em diversos países, entre eles o Brasil, mas as taxas de incremento no pós-guerra foram ainda maiores do que as observadas no início do século. Constatou-se, por fim, que dados provenientes da antropometria militar são os mais utilizados para estimativas de TSE.This paper presents a literature review of secular height trends. The principal topics included were definition of the phenomenon, use of historical data sets on height as an alternative approach for monitoring economic changes, the main theoretical explanations of the phenomenon, the beginning of military anthropometry, and past and current use in measuring secular height trends in recruits and children. The most important results showed that the positive secular trend can be attributed to environmental influences, especially improvements in health, economic, and social conditions. The mean reported rates in height increases varied with age, socioeconomic status, and country, so one must exercise caution in drawing inferences. World War II slowed the trend in several countries

  3. Manganese concentrations in drinking water from villages near banana plantations with aerial mancozeb spraying in Costa Rica: Results from the Infants' Environmental Health Study (ISA).

    Science.gov (United States)

    van Wendel de Joode, Berna; Barbeau, Benoit; Bouchard, Maryse F; Mora, Ana María; Skytt, Åsa; Córdoba, Leonel; Quesada, Rosario; Lundh, Thomas; Lindh, Christian H; Mergler, Donna

    2016-08-01

    Elevated manganese (Mn) in drinking water has been reported worldwide. While, naturally occurring Mn in groundwater is generally the major source, anthropogenic contamination by Mn-containing fungicides such as mancozeb may also occur. The main objective of this study was to examine factors associated with Mn and ethylenethiourea (ETU), a degradation product of mancozeb, in drinking water samples from villages situated near banana plantations with aerial spraying of mancozeb. Drinking water samples (n = 126) were obtained from 124 homes of women participating in the Infants' Environmental Health Study (ISA, for its acronym in Spanish), living nearby large-scale banana plantations. Concentrations of Mn, iron (Fe), arsenic (As), lead (Pb), cadmium (Cd) and ethylenethiourea (ETU), a degradation product of mancozeb, were measured in water samples. Only six percent of samples had detectable ETU concentrations (limit of detection (LOD) = 0.15 μg/L), whereas 94% of the samples had detectable Mn (LOD = 0.05 μg/L). Mn concentrations were higher than 100 and 500 μg/L in 22% and 7% of the samples, respectively. Mn was highest in samples from private and banana farm wells. Distance from a banana plantation was inversely associated with Mn concentrations, with a 61.5% decrease (95% CI: -97.0, -26.0) in Mn concentrations for each km increase in distance. Mn concentrations in water transported with trucks from one village to another were almost 1000 times higher than Mn in water obtained from taps in houses supplied by the same well but not transported, indicating environmental Mn contamination. Elevated Mn in drinking water may be partly explained by aerial spraying of mancozeb; however, naturally occurring Mn in groundwater, and intensive agriculture may also contribute. Drinking water risk assessment for mancozeb should consider Mn as a health hazard. The findings of this study evidence the need for health-based World Health Organization (WHO) guidelines on Mn in

  4. Acesso livre à informação científica digital: dificuldades e tendências

    Directory of Open Access Journals (Sweden)

    Claudia Regina Ziliotto Bomfá

    Full Text Available O artigo discute a questão do acesso livre à informação científica digital. São discutidos aspectos conceituais do acesso livre e apresentados os principais movimentos nacionais e internacionais em favor do acesso livre. Identificam-se repositórios de pesquisas científicas baseados no movimento de acesso livre e apresentam-se dificuldades e tendências. Conclui-se sinalizando mudanças no processo de comunicação científica, com ênfase na amplitude, rapidez e transparência no acesso livre à informação científica.

  5. Consequence of nanofluid on peristaltic transport of a hyperbolic tangent fluid model in the occurrence of apt (tending) magnetic field

    International Nuclear Information System (INIS)

    Akram, Safia; Nadeem, S.

    2014-01-01

    In the current study, sway of nanofluid on peristaltic transport of a hyperbolic tangent fluid model in the incidence of tending magnetic field has been argued. The governing equations of a nanofluid are first modeled and then simplified under lubrication approach. The coupled nonlinear equations of temperature and nano particle volume fraction are solved analytically using a homotopy perturbation technique. The analytical solution of the stream function and pressure gradient are carried out using perturbation technique. The graphical results of the problem under discussion are also being brought under consideration to see the behavior of various physical parameters. - Highlights: • The main motivation of this work is that we want to see the behavior of nanofluids in peristaltic flows. • In literature few articles are available on this, but no article is available in asymmetric channel on the new fluid model hyperbolic tangent fluid. • So we want to fill the gap in literature studying this

  6. Consequence of nanofluid on peristaltic transport of a hyperbolic tangent fluid model in the occurrence of apt (tending) magnetic field

    Energy Technology Data Exchange (ETDEWEB)

    Akram, Safia, E-mail: safia_akram@yahoo.com [Department of Basic Sciences, MCS, National University of Sciences and Technology, Rawalpindi 46000 (Pakistan); Nadeem, S. [Department of Mathematics, Quaid-i-Azam University 45320, Islamabad 44000 (Pakistan)

    2014-05-01

    In the current study, sway of nanofluid on peristaltic transport of a hyperbolic tangent fluid model in the incidence of tending magnetic field has been argued. The governing equations of a nanofluid are first modeled and then simplified under lubrication approach. The coupled nonlinear equations of temperature and nano particle volume fraction are solved analytically using a homotopy perturbation technique. The analytical solution of the stream function and pressure gradient are carried out using perturbation technique. The graphical results of the problem under discussion are also being brought under consideration to see the behavior of various physical parameters. - Highlights: • The main motivation of this work is that we want to see the behavior of nanofluids in peristaltic flows. • In literature few articles are available on this, but no article is available in asymmetric channel on the new fluid model hyperbolic tangent fluid. • So we want to fill the gap in literature studying this.

  7. Reestruturação produtiva e acidentes de trabalho no Brasil: estrutura e tendências

    Directory of Open Access Journals (Sweden)

    Wünsch Filho Victor

    1999-01-01

    Full Text Available A incidência de acidentes de trabalho no Brasil apresenta tendência decrescente nas duas últimas décadas. A mortalidade também é decrescente, porém de forma menos acentuada. O subregistro tem sido o principal argumento para explanar tal fato. O estudo das séries temporais com base em dados secundários de 1970 a 1995 revela que a incidência de acidentes de trabalho é sensível às flutuações cíclicas da economia e vincula-se, em particular, ao nível de atividade industrial. Detectou-se uma correlação linear positiva (r = 0,80 entre a proporção de pessoas ocupadas na produção industrial e a incidência de acidentes em 14 estados brasileiros. A recessão econômica durante a década de 80 gerou desemprego. A queda da oferta de empregos formais no setor industrial ­ com maiores riscos de acidentes, foi acentuada pelo processo de reestruturação produtiva e a incorporação crescente da informática e da robótica em diferentes processos industriais. Como conseqüência houve o deslocamento de um maior volume de força de trabalho para o setor terciário ­ com menor risco de acidentes. Estes fatos foram determinantes na tendência dos acidentes de trabalho observada neste período de 25 anos.

  8. Reestruturação produtiva e acidentes de trabalho no Brasil: estrutura e tendências

    Directory of Open Access Journals (Sweden)

    Victor Wünsch Filho

    Full Text Available A incidência de acidentes de trabalho no Brasil apresenta tendência decrescente nas duas últimas décadas. A mortalidade também é decrescente, porém de forma menos acentuada. O subregistro tem sido o principal argumento para explanar tal fato. O estudo das séries temporais com base em dados secundários de 1970 a 1995 revela que a incidência de acidentes de trabalho é sensível às flutuações cíclicas da economia e vincula-se, em particular, ao nível de atividade industrial. Detectou-se uma correlação linear positiva (r = 0,80 entre a proporção de pessoas ocupadas na produção industrial e a incidência de acidentes em 14 estados brasileiros. A recessão econômica durante a década de 80 gerou desemprego. A queda da oferta de empregos formais no setor industrial com maiores riscos de acidentes, foi acentuada pelo processo de reestruturação produtiva e a incorporação crescente da informática e da robótica em diferentes processos industriais. Como conseqüência houve o deslocamento de um maior volume de força de trabalho para o setor terciário com menor risco de acidentes. Estes fatos foram determinantes na tendência dos acidentes de trabalho observada neste período de 25 anos.

  9. Tendência Pedagógica Progressista Libertária – Uma breve apresentação

    Directory of Open Access Journals (Sweden)

    Kathlen Luana de Oliveira

    2011-10-01

    Full Text Available O presente texto versa sobre a tendência pedagógica progressista libertária. Tem como objetivo apresentar o contexto no qual surgiram os princípios libertários para, então, abordar as críticas e a proposta educacional dessa tendência. Brevemente, será exposta a Pedagogia Libertária norteada pela anarquia, pela crítica institucional, porém com propostas de práticas educativas construídas a partir da autogestão e da solidariedade. Nesse sentido, as contribuições de Lobrot, Tragtenberg serão delineadas frente aos desafios concretos e possíveis da proposta libertária.

  10. A European study on alcohol and drug use among young drivers: the TEND by Night study design and methodology

    Directory of Open Access Journals (Sweden)

    Siliquini Roberta

    2010-04-01

    Full Text Available Abstract Background Young individuals are the age group with the highest risk of car accidents. One of main explanations relies on the use of psychoactive substances (alcohol, illegal and medicinal drugs, which are known to be major risk factors of road accidents, and whose consumption is almost universally more common among younger drivers. Although the correlation between psychoactive substances use and decrease in driving performance has been established in controlled experimental or laboratory settings, few studies were conducted in naturalistic circumstances. The TEND by Night project has been designed to evaluate the relationship between driving performance and psychoactive substances assumption in young drivers enrolled at typical places of consumption. Methods/Design The TEND by Night project, endorsed by the European Commission, is a multidisciplinary, multi-centric, cross-sectional study conducted in six European countries (Italy, Belgium/Netherlands, Bulgaria, Spain, Poland and Latvia. The study population consists of 5000 young drivers aged 16-34 years, attending recreational sites during weekend nights. The intervention is based on the portal survey technique and includes several steps at the entrance and exit of selected sites, including the administration of semi-structured questionnaires, breath alcohol test, several drug assumption test, and measurement of the reaction time using a driving simulator. The main outcome is the difference in reaction time between the entrance and exit of the recreation site, and its correlation with psychoactive substances use. As a secondary outcome it will be explored the relationship between reaction time difference and the amount of consumption of each substance. All analyses will be multivariate. Discussion The project methodology should provide some relevant advantages over traditional survey systems. The main strengths of the study include the large and multicentric sample, the objective

  11. Stand tending and root rot in Norway spruce stands - economical effects caused by root rot at different thinning regimes

    International Nuclear Information System (INIS)

    Johansson, Mats

    1997-01-01

    This report is divided into three parts: 1) a literature study describing the most common fungi causing rot in wood and descriptions of various strategies to reduce economic loss from root rot, 2) a check of a model describing the development of butt rot in pure Norway spruce plantations in southern Sweden, and 3) simulated economic effects of root rot in stands with various stand tending. The rot model was used to estimate future rot frequencies in the economic calculations. In order to avoid overestimations of rot frequencies, the calculations were also executed when assuming slower growth of rot than shown in the model. When analysing the economical effects of rot, the following three thinning programmes were used: Program 1: thinning at the ages of 30- and 45 years. Final felling at the ages 50-, 55-, 60-, 65-, and 70 years. Program 2: thinning at the ages of 40- and 60- years. Final felling at the ages 65 and 75 years. Program 3: thinning at the ages of 30-, 40-, 55-, and 70 years. Final felling at the ages 80 and 90 years. With an interest rate of 3%, programme 2 (final felling at the age of 65 years) had the highest value at present. This result was valid when presuming butt rot in the stand as well as when presuming no butt rot in the stand. There was a small difference between the value at present in programme 1 (final felling at the age of 60 years) and in programme 3 (final felling at the age of 80 years). When presuming butt rot in the stand, the value at present in programme 3 decreased somewhat more in comparison to the value at present in programme 1. Compared to no butt rot in the stand, the optimal final felling time appeared five to ten years earlier when assuming butt rot in the stand. Stand tending programme 1 and an interest rate of 3% were used. Interest rates 2 and 4% did not indicate shorter rotation. The calculated optimal time of final felling appeared at the same stand age whether assuming rot preset or not. The results in this study

  12. Derivative chameleons

    International Nuclear Information System (INIS)

    Noller, Johannes

    2012-01-01

    We consider generalized chameleon models where the conformal coupling between matter and gravitational geometries is not only a function of the chameleon field φ, but also of its derivatives via higher order co-ordinate invariants (such as ∂ μ φ∂ μ φ,□φ,...). Specifically we consider the first such non-trivial conformal factor A(φ,∂ μ φ∂ μ φ). The associated phenomenology is investigated and we show that such theories have a new generic mass-altering mechanism, potentially assisting the generation of a sufficiently large chameleon mass in dense environments. The most general effective potential is derived for such derivative chameleon setups and explicit examples are given. Interestingly this points us to the existence of a purely derivative chameleon protected by a shift symmetry for φ → φ+c. We also discuss potential ghost-like instabilities associated with mass-lifting mechanisms and find another, mass-lowering and instability-free, branch of solutions. This suggests that, barring fine-tuning, stable derivative models are in fact typically anti-chameleons that suppress the field's mass in dense environments. Furthermore we investigate modifications to the thin-shell regime and prove a no-go theorem for chameleon effects in non-conformal geometries of the disformal type

  13. Derivative chameleons

    Energy Technology Data Exchange (ETDEWEB)

    Noller, Johannes, E-mail: johannes.noller08@imperial.ac.uk [Theoretical Physics, Blackett Laboratory, Imperial College London, Prince Consort Road, London, SW7 2BZ (United Kingdom)

    2012-07-01

    We consider generalized chameleon models where the conformal coupling between matter and gravitational geometries is not only a function of the chameleon field φ, but also of its derivatives via higher order co-ordinate invariants (such as ∂{sub μ}φ∂{sup μ}φ,□φ,...). Specifically we consider the first such non-trivial conformal factor A(φ,∂{sub μ}φ∂{sup μ}φ). The associated phenomenology is investigated and we show that such theories have a new generic mass-altering mechanism, potentially assisting the generation of a sufficiently large chameleon mass in dense environments. The most general effective potential is derived for such derivative chameleon setups and explicit examples are given. Interestingly this points us to the existence of a purely derivative chameleon protected by a shift symmetry for φ → φ+c. We also discuss potential ghost-like instabilities associated with mass-lifting mechanisms and find another, mass-lowering and instability-free, branch of solutions. This suggests that, barring fine-tuning, stable derivative models are in fact typically anti-chameleons that suppress the field's mass in dense environments. Furthermore we investigate modifications to the thin-shell regime and prove a no-go theorem for chameleon effects in non-conformal geometries of the disformal type.

  14. Electricity derivatives

    CERN Document Server

    Aïd, René

    2015-01-01

    Offering a concise but complete survey of the common features of the microstructure of electricity markets, this book describes the state of the art in the different proposed electricity price models for pricing derivatives and in the numerical methods used to price and hedge the most prominent derivatives in electricity markets, namely power plants and swings. The mathematical content of the book has intentionally been made light in order to concentrate on the main subject matter, avoiding fastidious computations. Wherever possible, the models are illustrated by diagrams. The book should allow prospective researchers in the field of electricity derivatives to focus on the actual difficulties associated with the subject. It should also offer a brief but exhaustive overview of the latest techniques used by financial engineers in energy utilities and energy trading desks.

  15. Sistemas ERP: características, custos e tendências ERP systems: characteristics, implementation cost, tendencies

    Directory of Open Access Journals (Sweden)

    Thais Cássia Cabral Padilha

    2005-04-01

    Full Text Available Muitas empresas estão adotando Sistemas ERP devido a várias razões, tais como: decepção com sistemas incompatíveis, incapacidade do Departamento de Tecnologia de Informação em realizar a integração entre os sistemas existentes atualmente na empresa e outros motivos que influenciam diretamente a competitividade da Empresa. Neste contexto, este artigo apresenta as principais características de Sistemas ERP, suas vantagens e desvantagens, bem como os custos envolvidos na sua implementação. Finalmente, as tendências e o futuro de Sistemas ERP são comentados.Several Companies are adopting ERP systems due to different reasons, such as: deceptions with incompatible systems, incapacity of Technology Information Department of doing integration among current systems, and other reasons which have direct influence in Company's competitiveness. In this context, this work presents the main ERP system characteristics, and the advantages, disadvantages and costs involved with its implementation. Besides this, the tendencies and the future for ERP systems are commented.

  16. Tendências De Teses e Dissertações Sobre Educação em Astronomia No Brasil

    Science.gov (United States)

    Bretones, Paulo Sergio; Megid Neto, Jorge

    2005-07-01

    Apresentam-se os resultados de uma pesquisa do tipo estado da arte sobre teses e dissertações defendidas no Brasil e relativas ao ensino de Astronomia, com objetivo de identificar essa produção e conhecer as principais tendências da pesquisa nesse campo. Foram localizadas 13 dissertações de mestrado e 3 teses de doutorado, as quais foram estudadas em função dos seguintes aspectos: isntituição, ano de defesa, nível escolar abrangido no estudo, foco temático do estudo e gênero de trabalho acadêmico. Pretende-se assim colaborar com a divulgação ampla da produção acadêmica na área. Ao mesmo tempo o estudo possibilita, a partir de investigações decorrentes, apontar as contribuições dessa produção para o ensino e sinalizar com necessidades a serem supridas por futuras pesquisas.

  17. The effects of stress and affiliation on social decision-making: Investigating the tend-and-befriend pattern.

    Science.gov (United States)

    Steinbeis, Nikolaus; Engert, Veronika; Linz, Roman; Singer, Tania

    2015-12-01

    The prevalence of psychosocial stress in Western societies is constantly on the rise. Its influence on social decision-making, however, remains poorly understood. Whereas, it is known that stress triggers psychological and physiological defense mechanisms, indications of such patterns in social decisions are ambivalent. We sought to elucidate the underlying mechanisms of stress-induced social decisions. We recruited 145 men, who were individually exposed to either a psychosocial stressor or a control condition, while primed with affiliation by interacting either with members of an in- or an out-group. We found that stressed participants were less trusting and engaged in less costly punishment compared to the non-stressed control group. Interacting with out-group members led to less reciprocity and more spiteful punishment. There was no interaction between stress and the affiliation conditions in any of the used social-decision-making paradigms. Lastly, while stress-reactive cortisol levels had no effect on trust behavior, higher baseline cortisol was correlated with greater trust. Our findings suggest that previous ambiguities in data reported on the influence of stress on social decisions, namely tend-and-befriend behavior may have arisen through critical social confounds in the induction of stress. When controlling for potential social confounds, stress may trigger fight-or-flight behavior as indicated by increased social anxiety. These findings highlight the considerable context-dependence of psychosocial stress and its effects on social behavior. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Patients with chronic headache tend to have more psychological symptoms than those with sporadic episodes of pain

    Directory of Open Access Journals (Sweden)

    Maria Aparecida Junqueira Zampieri

    2014-08-01

    Full Text Available There are controversial associations between headaches and psychological symptoms. Objective To design a profile of neuroticism, a term that groups variables related to negative personality traits, in patients with chronic daily headache (CDH when compared to episodic migraine (EM patients, applying the Factorial Scale of Emotional Adjustment/Neuroticism (NFS. Method One hundred adult patients with CDH and forty with EM answered the NFS. Results Comorbidities of subtypes of neuroticism (p=0.006 were more common in chronic daily headache patients, with three or more disorders (p=0.0002: dependent personality disorder (p=0.0001, anxiety, reduced concentration and production (p=0.0008, depression (p<0.0001, suicidal ideation (p=0.0008 and hopelessness even without depression (p<0.0001. Conclusion Patients with CDH tend to have dependent personality disorder, low production and concentration, anxiety, depression, suicidal ideation and hopelessness, superimposing two or more psychological disorders. These factors should be pondered for a better resolution in the treatment of CDH.

  19. The Eosinophil Count Tends to Be Negatively Associated with Levels of Serum Glucose in Patients with Adrenal Cushing Syndrome

    Directory of Open Access Journals (Sweden)

    Younghak Lee

    2017-09-01

    Full Text Available BackgroundCushing syndrome is characterized by glucose intolerance, cardiovascular disease, and an enhanced systemic inflammatory response caused by chronic exposure to excess cortisol. Eosinopenia is frequently observed in patients with adrenal Cushing syndrome, but the relationship between the eosinophil count in peripheral blood and indicators of glucose level in patients with adrenal Cushing syndrome has not been determined.MethodsA retrospective study was undertaken of the clinical and laboratory findings of 40 patients diagnosed with adrenal Cushing syndrome at Chungnam National University Hospital from January 2006 to December 2016. Clinical characteristics, complete blood cell counts with white blood cell differential, measures of their endocrine function, description of imaging studies, and pathologic findings were obtained from their medical records.ResultsEosinophil composition and count were restored by surgical treatment of all of the patients with adrenal Cushing disease. The eosinophil count was inversely correlated with serum and urine cortisol, glycated hemoglobin, and inflammatory markers in the patients with adrenal Cushing syndrome.ConclusionSmaller eosinophil populations in patients with adrenal Cushing syndrome tend to be correlated with higher levels of blood sugar and glycated hemoglobin. This study suggests that peripheral blood eosinophil composition or count may be associated with serum glucose levels in patients with adrenal Cushing syndrome.

  20. The Eosinophil Count Tends to Be Negatively Associated with Levels of Serum Glucose in Patients with Adrenal Cushing Syndrome.

    Science.gov (United States)

    Lee, Younghak; Yi, Hyon Seung; Kim, Hae Ri; Joung, Kyong Hye; Kang, Yea Eun; Lee, Ju Hee; Kim, Koon Soon; Kim, Hyun Jin; Ku, Bon Jeong; Shong, Minho

    2017-09-01

    Cushing syndrome is characterized by glucose intolerance, cardiovascular disease, and an enhanced systemic inflammatory response caused by chronic exposure to excess cortisol. Eosinopenia is frequently observed in patients with adrenal Cushing syndrome, but the relationship between the eosinophil count in peripheral blood and indicators of glucose level in patients with adrenal Cushing syndrome has not been determined. A retrospective study was undertaken of the clinical and laboratory findings of 40 patients diagnosed with adrenal Cushing syndrome at Chungnam National University Hospital from January 2006 to December 2016. Clinical characteristics, complete blood cell counts with white blood cell differential, measures of their endocrine function, description of imaging studies, and pathologic findings were obtained from their medical records. Eosinophil composition and count were restored by surgical treatment of all of the patients with adrenal Cushing disease. The eosinophil count was inversely correlated with serum and urine cortisol, glycated hemoglobin, and inflammatory markers in the patients with adrenal Cushing syndrome. Smaller eosinophil populations in patients with adrenal Cushing syndrome tend to be correlated with higher levels of blood sugar and glycated hemoglobin. This study suggests that peripheral blood eosinophil composition or count may be associated with serum glucose levels in patients with adrenal Cushing syndrome. Copyright © 2017 Korean Endocrine Society

  1. Polycystic ovary syndrome patients with high BMI tend to have functional disorders of androgen excess: a prospective study.

    Science.gov (United States)

    Yuan, Chun; Liu, Xiaoqiang; Mao, Yundong; Diao, Feiyang; Cui, Yugui; Liu, Jiayin

    2016-05-01

    Biochemical or clinical changes of hyperandrogenism are important elements of polycystic ovary syndrome (PCOS). There is currently no consensus on the definition and diagnostic criteria of hyperandrogenism in PCOS. The aim of this study was to investigate the complex symptoms of hyperandrogenic disorders and the correlations between metabolism and hyperandrogenism in patients with PCOS from an outpatient reproductive medicine clinic in China. We conducted a case control study of 125 PCOS patients and 130 controls to evaluate differences in body mass index (BMI), total testosterone (TT), modified Ferriman-Gallwey hirsutism score, sex hormone binding globulin (SHBG), homeostasis model assessment-estimated insulin resistance (HOMA-IR) and free androgen index (FAI) between PCOS patients and controls and subgroups of PCOS. The prevalence of acne and hirsutism did not differ significantly between the hyperandrogenic and non-hyperandrogenic subgroup. Patients with signs of hyperandrogenism had significantly higher BMI (P PCOS patients. Our results suggest that PCOS patients with high BMI tend to have functional disorders of androgen excess; therefore, BMI may be a strong predictor of hyperandrogenism in PCOS. © 2016 the Journal of Biomedical Research. All rights reserved.

  2. Carbon dioxide sensing in the social context: Leaf-cutting ants prefer elevated CO2 levels to tend their brood.

    Science.gov (United States)

    Römer, Daniela; Bollazzi, Martin; Roces, Flavio

    2018-05-18

    Social insects show temperature and humidity preferences inside their nests to successfully rear brood. In underground nests, ants also encounter rising CO 2 concentrations with increasing depth. It is an open question whether they use CO 2 as a cue to decide where to place and tend the brood. Leaf-cutting ants do show CO 2 preferences for the culturing of their symbiotic fungus. We evaluated their CO 2 choices for brood placement in laboratory experiments. Workers of Acromyrmex lundii in the process of relocating brood were offered a binary choice consisting of two interconnected chambers with different CO 2 concentrations. Values ranged from atmospheric to high concentrations of 4% CO 2 . The CO 2 preferences shown by workers for themselves and for brood placement were assessed by quantifying the number of workers and relocated brood in each chamber. Ants showed clear CO 2 preferences for brood placement. They avoided atmospheric levels, 1% and 4% CO 2 , and showed a preference for levels of 3%. This is the first report of CO 2 preferences for the maintenance of brood in social insects. The observed preferences for brood location were independent of the workers' own CO 2 preferences, since they showed no clear-cut pattern. Workers' CO 2 preferences for brood maintenance were slightly higher than those reported for fungus culturing, although brood is reared in the same chambers as the fungus in leaf-cutting ant nests. Workers' choices for brood placement in natural nests are likely the result of competing preferences for other environmental factors more crucial for brood survival, aside from those for CO 2 . Copyright © 2018 Elsevier Ltd. All rights reserved.

  3. Whose landscape? - An anthropological perspective on landscape perception in reindeer tending (In Swedish with Summary in English

    Directory of Open Access Journals (Sweden)

    Anna Järpe

    2005-04-01

    Full Text Available When we talk publicly about landscape and land use, both in legal and in popular contexts, the evaluation of our natural environment is usually based on an industrial concept of land and landscape. "Nature" is seen as a resource to be used or managed in different ways. My research originates in a questioning of this assumption: can we take for granted that the same perceptions and evaluations are shared by all concerned parties? In this article, I will use an ecologic anthropological perspective to consider the livelihood of reindeer tending and suggest an alternative to what can be called a scientific understanding of the world. I maintain that the relations that people have with their environment, and the values that they ascribe to it, are perceptions that are shaped and affected in our interactions with the surrounding world, and that these perceptions vary between different groups of people. Land use, land rights, access to fishing waters, and who gets to hunt what; these are not only questions about how we should manage the landscape, but also about whose landscape we are managing. Arguing that the reindeer tenders' landscape is a shifting mosaic of varying conditions that they must relate to rather than an object to be used and controlled by human interests, I want to show how anthropological research can provide an insight into the different perspectives and modes of understanding that we need to consider in the formulation of future policies and laws. At least if we want to resolve land use conflicts in contested areas fairly and on a sustainable long-term basis.

  4. Mortalidade infantil em duas coortes de base populacional no Sul do Brasil: tendências e diferenciais

    Directory of Open Access Journals (Sweden)

    Menezes Ana M. B.

    1996-01-01

    Full Text Available Estudou-se a tendência temporal da mortalidade infantil através de dois estudos de coorte realizados em Pelotas, Rio Grande do Sul, em 1982 e 1993. Ambas coortes incluíram todos os nascimentos hospitalares e óbitos verificados através de visitas regulares aos hospitais, cartórios e cemitérios. As informações sobre a causa de morte foram obtidas através de entrevistas com pediatras, revisão do prontuário, necrópsias e entrevista com os pais das crianças. O coeficiente de mortalidade infantil caiu de 36,4 por mil nascidos vivos para 21,1 na década. As principais causas de mortalidade infantil em 1993 foram as perinatais, malformações congênitas, diarréia e infecções respiratórias. Crianças com baixo peso ao nascer apresentaram mortalidade 12 vezes maior do que crianças com peso adequado, e crianças pré-termo, duas vezes mais do que crianças com retardo de crescimento intra-uterino. Crianças de famílias com renda baixa (um salário mínimo apresentaram mortalidade sete vezes superior àquelas com renda alta (10 salários mínimos. A mortalidade de crianças de baixo peso ao nascer e alta renda familiar decresceu em 67%, contra apenas 36% para as de baixa renda. Conclui-se que, mesmo com uma queda expressiva da mortalidade infantil na década, persistem importantes desigualdades sociais.

  5. Growth Potential of Subdural Hematomas Under Clinical Observation: Which Subdural Hematomas Tend to Grow and Why They Do.

    Science.gov (United States)

    Asan, Ziya

    2018-05-01

    To study the prognoses of patients with subdural hematoma (SDH) who were not operated on at the time of the first diagnosis and the causes of enlarged hematomas in some patients during the follow-up period. The records, service files, and radiologic examination results of the patients with diagnoses of SDH were reviewed. The SDH patients were recorded under 5 different categories: acute SDH (ASDH), subacute SDH (SSDH), chronic SDH (CSDH), acute component with chronic SDH (A-CSDH), and subacute component with chronic SDH (S-CSDH). The symptoms, clinical findings, and progression in the patients were correlated with radiologic examinations. A total of 291 patients received diagnoses of SDHs: 80 patients with acute, 29 patients with subacute, and 163 patients with chronic hematoma. Thirty-five patients had diagnoses of SDH with a combination of different components. It was determined that in the follow-up period, patients with A-CSDH showed the greatest increase in hematoma size over time and required surgical intervention the most often. SDHs reveal different prognoses in different age groups. Multicomponent SDHs are within the group that shows the greatest increase in size in the follow-up period. SDHs and CSDHs cause recurrent hemorrhages by sustaining the tension on the bridging veins. The greater the hematoma volume, the greater the growth potential of the hematoma tends to be. CSDHs that do not manifest changes in volume for a long time can be monitored without surgical intervention as long as the clinical picture remains stable. Copyright © 2018 Elsevier Inc. All rights reserved.

  6. Dynamic event Tress applied to sequences Full Spectrum LOCA. Calculating the frequency of exceedance of damage by integrated Safety Analysis Methodology; Arboles de sucesos dinamicos aplicados a secuencias Full Spectrum LOCA. Calculo de la frequencia de excedencia del dano mediante la metodologia Analisis Integrados de Seguridad (ISA)

    Energy Technology Data Exchange (ETDEWEB)

    Gomez-Magan, J. J.; Fernandez, I.; Gil, J.; Marrao, H.; Queral, C.; Gonzalez-Cadelo, J.; Montero-Mayorga, J.; Rivas, J.; Ibane-Llano, C.; Izquierdo, J. M.; Sanchez-Perea, M.; Melendez, E.; Hortal, J.

    2013-09-01

    The Integrated Safety Analysis (ISA) methodology, developed by the Spanish Nuclear Safety council (CSN), has been applied to obtain the dynamic Event Trees (DETs) for full spectrum Loss of Coolant Accidents (LOCAs) of a Westinghouse 3-loop PWR plant. The purpose of this ISA application is to obtain the Damage Exceedance Frequency (DEF) for the LOCA Event Tree by taking into account the uncertainties in the break area and the operator actuation time needed to cool down and de pressurize reactor coolant system by means of steam generator. Simulations are performed with SCAIS, a software tool which includes a dynamic coupling with MAAP thermal hydraulic code. The results show the capability of the ISA methodology to obtain the DEF taking into account the time uncertainty in human actions. (Author)

  7. Mediações e midiatização do consumo alimentar: #taeq e tendência da saudabilidade na rede

    Directory of Open Access Journals (Sweden)

    Lívia Silva de Souza

    2018-01-01

    Full Text Available Na perspectiva das tendências do consumo alimentar conforme Madi et al (2010, observamos os modos como as cinco tendências globais da alimentação (sensorialidade, saudabilidade, sustentabilidade, praticidade e confiabilidade comportam-se na circulação midiática nas redes. Aqui apresentamos os resultados quanto à tendência da saudabilidade, a partir da observação das interações em torno da marca Taeq, por meio da hashtag #taeq na rede social Instagram.

  8. Políticas de formação de professores: reflexões e tendências

    Directory of Open Access Journals (Sweden)

    Sonia Regina Landini

    2004-01-01

    Full Text Available No complexo social os valores e as características culturais, produzidos na prática social, expressam a direção a ser dada à formação tendo em vista os processos de reprodução do ser social. No caso do capitalismo, o elemento fundante das relações sociais é a economia, de tempo e na produção de mais-valia. No desenvolvimento cotidiano de suas atividades, os homens, ao buscarem a realização de si mesmos enquanto membros de uma sociedade reagem às formas exploratórias que retiram dos Sujeitos a plena possibilidade de realização. No caso da formação de professores, a tendência de formação de um profissional capaz de lidar com situações singulares. No entanto, a singularidade deve ser compreendida a partir de sua relação com a totalidade social. O desafio que se coloca parece se concentrar no resgate das mediações, dos mecanismos de incorporação e nos de resistência e negação, presentes no cotidiano. In the social complex the cultural values and characteristics, produced in social practice, express the direction to be given to the formation, in view of the processes of reproduction of the social being. In the case of the capitalism, the most important element of the social relations is the economy of time and in the production of plus-value. In the daily development of its activities, the men, when searching the accomplishment of itself as members of a society, react to the exploratórias forms that remove of the Citizens the full possibility of accomplishment. In the case of the teachers formation, the trend of formation means a professional capable to deal with singular situations. However, the singularity must be understood from its relation with the social totality. The challenge seems to be concentrate in the rescue of the mediation, the mechanisms of incorporation, as well as the mechanisms of daily resistance and negation.

  9. Tendências no ensino da epidemiologia no Brasil Trends in the teaching of epidemiology in Brazil

    Directory of Open Access Journals (Sweden)

    Rita Barradas Barata

    1997-01-01

    Full Text Available O ensino da epidemiologia teve início no Brasil na década de 20 e sempre foi voltado para a saúde pública. Na década de 70, o ensino de epidemiologia passou por um crescimento em nível de pós-graduação. Os anos 80 foram marcados pela "epidemiologia social", que incorporava as ciências sociais e seus métodos; a segunda metade da década foi marcada pelo desenvolvimento das técnicas da bioestatística. No momento atual, a definição de diretrizes para o ensino da epidemiologia depende da reflexão acerca de vários pontos, entre os quais a reformulação ou extinção dos programas de residência médica em medicina preventiva, medicina social ou saúde coletiva; implantação de programas de mestrado e doutorado exclusivamente em ; oposição entre formação instrumental e formação teórica; e desenvolvimento de estratégias para o fortalecimento de novos grupos de docentes em instituições de ensino nas regiões mais pobres do país. Existe uma tendência positiva de aproximação entre instituições de ensino e serviços de saúde, tanto para o cumprimento de tarefas de ensino e formação de pessoal, quanto para o assessoramento técnico no planejamento, organização e avaliação de programas. Em relação aos profissionais que atuam em serviços de saúde, a efetividade dos programas em epidemiologia depende da capacidade dos docentes de trabalharem com situações de ensino-aprendizagem que facilitem a apreensão por parte dos alunos nas condições reais de seu trabalho, situações concretas em que a teorização seja uma decorrência natural.The teaching of epidemiology in Brazil began in the 1920s and has always been connected to public health. The 1970s witnessed an expansion in the number of graduate-level courses in epidemiology. The 1980s were characterized by "social epidemiology," which incorporated the social sciences and their methods into epidemiology; the second half of the decade was marked by the

  10. The sleep of elite athletes at sea level and high altitude: a comparison of sea-level natives and high-altitude natives (ISA3600)

    Science.gov (United States)

    Roach, Gregory D; Schmidt, Walter F; Aughey, Robert J; Bourdon, Pitre C; Soria, Rudy; Claros, Jesus C Jimenez; Garvican-Lewis, Laura A; Buchheit, Martin; Simpson, Ben M; Hammond, Kristal; Kley, Marlen; Wachsmuth, Nadine; Gore, Christopher J; Sargent, Charli

    2013-01-01

    Background Altitude exposure causes acute sleep disruption in non-athletes, but little is known about its effects in elite athletes. The aim of this study was to examine the effects of altitude on two groups of elite athletes, that is, sea-level natives and high-altitude natives. Methods Sea-level natives were members of the Australian under-17 soccer team (n=14). High-altitude natives were members of a Bolivian under-20 club team (n=12). Teams participated in an 18-day (19 nights) training camp in Bolivia, with 6 nights at near sea level in Santa Cruz (430 m) and 13 nights at high altitude in La Paz (3600 m). Sleep was assessed on every day/night using activity monitors. Results The Australians’ sleep was shorter, and of poorer quality, on the first night at altitude compared with sea level. Sleep quality returned to normal by the end of the first week at altitude, but sleep quantity had still not stabilised at its normal level after 2 weeks. The quantity and quality of sleep obtained by the Bolivians was similar, or greater, on all nights at altitude compared with sea level. The Australians tended to obtain more sleep than the Bolivians at sea level and altitude, but the quality of the Bolivians’ sleep tended to be better than that of the Australians at altitude. Conclusions Exposure to high altitude causes acute and chronic disruption to the sleep of elite athletes who are sea-level natives, but it does not affect the sleep of elite athletes who are high-altitude natives. PMID:24282197

  11. The sleep of elite athletes at sea level and high altitude: a comparison of sea-level natives and high-altitude natives (ISA3600).

    Science.gov (United States)

    Roach, Gregory D; Schmidt, Walter F; Aughey, Robert J; Bourdon, Pitre C; Soria, Rudy; Claros, Jesus C Jimenez; Garvican-Lewis, Laura A; Buchheit, Martin; Simpson, Ben M; Hammond, Kristal; Kley, Marlen; Wachsmuth, Nadine; Gore, Christopher J; Sargent, Charli

    2013-12-01

    Altitude exposure causes acute sleep disruption in non-athletes, but little is known about its effects in elite athletes. The aim of this study was to examine the effects of altitude on two groups of elite athletes, that is, sea-level natives and high-altitude natives. Sea-level natives were members of the Australian under-17 soccer team (n=14). High-altitude natives were members of a Bolivian under-20 club team (n=12). Teams participated in an 18-day (19 nights) training camp in Bolivia, with 6 nights at near sea level in Santa Cruz (430 m) and 13 nights at high altitude in La Paz (3600 m). Sleep was assessed on every day/night using activity monitors. The Australians' sleep was shorter, and of poorer quality, on the first night at altitude compared with sea level. Sleep quality returned to normal by the end of the first week at altitude, but sleep quantity had still not stabilised at its normal level after 2 weeks. The quantity and quality of sleep obtained by the Bolivians was similar, or greater, on all nights at altitude compared with sea level. The Australians tended to obtain more sleep than the Bolivians at sea level and altitude, but the quality of the Bolivians' sleep tended to be better than that of the Australians at altitude. Exposure to high altitude causes acute and chronic disruption to the sleep of elite athletes who are sea-level natives, but it does not affect the sleep of elite athletes who are high-altitude natives.

  12. Tendències de les publicacions informatives cientificomèdiques en l'era 2.0

    Directory of Open Access Journals (Sweden)

    González Pacanowski, Antonio

    2014-12-01

    Full Text Available En els últims anys ha crescut l'audiència que consulta continguts de salut en publicacions i mitjans a Internet, especialment a Europa i als Estats Units. S'ha passat d'un usuari d'Internet unidireccional en la comunicació a un escenari en el qual la multidireccionalitat i la instantaneïtat són constants. Els nous mitjans i la creació de plataformes d'intercanvi d'informació més especialitzada mostren que els recursos multimèdia i la interactivitat també poden donar-se en mitjans especialitzats i distants del públic general com ara informació sobre biomedicina i salut. Simultàniament, el canvi cap a actituds més solidàries i d'ajuda mútua aflora mitjançant les xarxes socials. Amb l'objectiu de traçar un escenari sobre el comportament de les audiències davant els continguts de caràcter científic, especialment els de tipus sanitari, s'analitzen en aquest treball els perfils i costums dels usuaris utilitzant referències estadístiques tant europees com nord-americanes. De la mateixa manera, s'identifica el mapa actual de cibermitjans relacionats amb la informació cientificomèdica segmentada en mitjans de comunicació generals, especialitzats i els propis del web 2.0, com ara blogs i mitjans cocreatius. Aquesta descripció permet orientar sobre les tendències que seguiran els públics diferents i segmentats, però ara interconnectats per les noves tecnologies, i sobre la transformació de l'arquitectura i les funcionalitats dels mitjans a Internet.En los últimos años ha crecido la audiencia que consulta contenidos de salud en publicaciones y medios en Internet, especialmente en Europa y Estados Unidos. Se ha pasado de un usuario de Internet unidireccional en la comunicación a un escenario en el que la multidireccionalidad y la instantaneidad son constantes. Los nuevos medios y la creación de plataformas de intercambio de información más especializada evidencian que los recursos multimedia y la interactividad tambi

  13. Tendência das séries temporais de precipitação da região sul do Brasil

    Directory of Open Access Journals (Sweden)

    Adilson Pinheiro

    2013-09-01

    Full Text Available O objetivo deste trabalho é avaliar a presença de tendências nas séries temporais de precipitação no Sul do Brasil. Foram analisadas séries temporais diárias, mensais e anuais de 18 estações pluviométricas. As distribuições de probabilidade normal e de extremos tipo I foram empregadas para análise dos dados. Foi, ainda, aplicado o teste de tendência de Mann-Kendall na detecção de tendências ou de variabilidades climáticas. Os resultados mostram uma tendência positiva dos máximos diários anuais ao longo do tempo, assim como significativa elevação dos totais mensais e anuais na maioria das estações. O teste de tendência de Mann-Kendal mostra mudanças estatisticamente significativas, ao nível de 95%, em 16 das 18 estações pluviométricas analisadas.

  14. Membrana de PLDLA-TMC como protetor na regeneração do tendão calcâneo: Estudo in vivo em coelhos

    Directory of Open Access Journals (Sweden)

    Julia Rezende Duek

    2014-06-01

    Full Text Available Um dos maiores problemas da cirurgia restauradora dos tendões flexores é evitar a formação de aderências, pois limita seu deslizamento. Assim, é muito desejável que a cicatrização ocorra o mais rápido possível, restaurando a capacidade de deslizamento dos tendões, sem limitações dos movimentos. O objetivo deste trabalho foi analisar a resistência do Tendão calcâneo, utilizando membrana de PLDLA-TMC como protetor da aderência dos tecidos adjacentes após implantes em coelhos New Zeland. Foram utilizados 20 coelhos, divididos em dois grupos, os quais foram submetidos à secção do tendão calcâneo e posterior sutura com técnica de Kessler modificada. No grupo A, logo após sutura o animal foi sacrificado e o tendão foi enviado para ensaio mecânico. Já no grupo B, após três semanas, os animais foram sacrificados e o material foi submetido à análise histológica. Os resultados obtidos a partir do ensaio mecânico mostraram melhora nos valores da resistência à tração dos implantes com a membrana, comparados aos apenas suturados. Na cicatrização da lesão, ocorreu melhor organização das fibras colágenas quando foi utilizado o polímero PLDLA-TMC, além de uma menor aderência cicatricial. Conclui-se que a membrana de PLDLA-TMC é promissora na reparação de lesões tendíneas.

  15. Tendências climáticas e produção de uva na região dos Vales da Uva Goethe

    Directory of Open Access Journals (Sweden)

    Álvaro José Back

    2012-04-01

    Full Text Available O objetivo deste trabalho foi avaliar tendências nas séries climáticas e nos índices agroclimáticos para o cultivo da videira na região dos Vales da Uva Goethe, em Santa Catarina. A região apresenta clima mesotérmico úmido. Foram utilizados dados de temperatura máxima e mínima do ar, do período de 1924 a 2010, e de precipitação pluvial, de 1955 a 2010. O teste de Mann‑Kendall foi utilizado para avaliar a tendência nas séries, cuja magnitude foi estimada pela declividade mediana determinada pelo teste de Theil-Sen. Foi observada tendência de aumento nas séries de temperatura mínima do ar, em escala anual, bem como nas estações do ano. Quanto à temperatura máxima, somente houve tendência de aumento na série de verão. Em relação aos índices agrometeorológicos, foi observada tendência de diminuição do número de geadas, diminuição do período entre a brotação e a colheita, aumento da soma térmica e dos índices de Huglin e de frio. Foram evidenciadas tendências de aumento da precipitação pluvial total anual e da precipitação no período de crescimento da videira, bem como aumento do número de dias, com chuva igual ou superior a 20 mm, e aumento na temperatura mínima e noturna.

  16. Sistemas de recuperação de informações e mecanismos de busca na web: panorama atual e tendências

    Directory of Open Access Journals (Sweden)

    Renato Rocha Souza

    Full Text Available Busca-se traçar um panorama das características básicas dos sistemas de recuperação de informações, apresentando seus modelos de recuperação mais comuns. São apresentados com ênfase especial os mecanismos de busca na web, seu estado atual de desenvolvimento e algumas tendências para o futuro. Dentre estas tendências, destacam-se notadamente aquelas introduzidas pelo Google, como o algoritmo pagerank, dentre outras inovações.

  17. Tendências hidrológicas anuais e sazonais na bacia do Rio Paraibuna, Parque Estadual da Serra do Mar (SP)

    OpenAIRE

    Vilanova,Mateus Ricardo Nogueira

    2014-01-01

    O presente trabalho avalia a existência de tendências monotônicas em séries anuais e sazonais de vazão e chuva, no trecho da Bacia do Rio Paraibuna localizado entre os Núcleos Cunha e Santa Virgínia, Parque Estadual da Serra do Mar (SP). O teste de Mann-Kendall foi aplicado a séries destas variáveis, em diversos intervalos no período de 1967 a 2011. Tendências negativas estatisticamente significativas foram detectadas nas séries de c...

  18. The prognostic value of the Tpeak-Tend interval in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction

    DEFF Research Database (Denmark)

    Haarmark, Christian; Hansen, Peter R; Vedel-Larsen, Esben

    2011-01-01

    INTRODUCTION: The Tpeak-Tend interval (TpTe) has been linked to increased arrhythmic risk. TpTe was investigated before and after primary percutaneous coronary intervention (pPCI) in patients with ST-segment elevation myocardial infarction (STEMI). METHOD: Patients with first-time STEMI treated...... with pPCI were included (n = 101; mean age 62 years; range 39-89 years; 74% men). Digital electrocardiograms were taken pre- and post-PCI, respectively. Tpeak-Tend interval was measured in leads with limited ST-segment deviation. The primary end point was all-cause mortality during 22 +/- 7 months (mean...

  19. Honest People Tend to Use Less—Not More—Profanity : Comment on Feldman et al.’s Study 1

    NARCIS (Netherlands)

    de Vries, Reinout Everhard; Hilbig, Benjamin E.; Zettler, Ingo; Dunlop, Patrick D.; Holtrop, Djurre; Lee, Kibeom; Ashton, Michael C.

    2017-01-01

    This article shows that the conclusion of Feldman et al.’s (2017) Study 1 that profane individuals tend to be honest is most likely incorrect. We argue that Feldman et al.’s conclusion is based on a commonly held but erroneous assumption that higher scores on Impression Management Scales, such as

  20. Insights into the 3D architecture of an active caldera ring-fault at Tendürek volcano through modeling of geodetic data

    KAUST Repository

    Vasyura-Bathke, Hannes; Nikkhoo, M.; Holohan, E.P.; Walter, T.R.

    2015-01-01

    of spatially dense InSAR time-series data, numerical models and sand-box experiments to determine the three-dimensional geometry and kinematics of a sub-surface ring-fault at Tendürek volcano in Turkey. The InSAR data reveal that the area within the ring

  1. Aspectos de imagem do xantoma do tendão calcâneo na ultrassonografia e ressonância magnética

    Directory of Open Access Journals (Sweden)

    Eloy de Ávila Fernandes

    2015-06-01

    Full Text Available O xantoma no tendão calcâneo é uma doença rara e tem uma alta associação com hiperlipidemia primária. O diagnóstico precoce é fundamental para o início do tratamento e para alterar o curso da doença. Os exames de imagem podem auxiliar nesse diagnóstico. Este estudo relata o caso de um homem de 60 anos apresentando nódulos indolores nos cotovelos e tendões calcâneos, sem crises típicas de gota, acompanhado no ambulatório de doenças microcristalinas da Unifesp para esclarecimento diagnóstico. Os testes laboratoriais solicitados apresentavam dislipidemia. Ultrassom (US mostrou espessamento difuso dos tendões calcâneos com áreas hipoecoicas. Ressonância magnética (RM mostrou espessamento difuso dos tendões, com áreas de sinal intermediário e padrão reticulado no interior. Os exames de imagem mostraram aspectos relevantes no diagnóstico de xantoma, auxiliando no diagnóstico diferencial.

  2. Tendências de temperaturas mínimas e máximas do ar no Estado de Minas Gerais

    Directory of Open Access Journals (Sweden)

    Léo Fernandes Ávila

    2014-04-01

    Full Text Available O objetivo deste trabalho foi avaliar tendências das temperaturas mínimas e máximas no Estado de Minas Gerais. Foram avaliados dados de 43 municípios, tendo-se considerado as escalas anual e sazonal - janeiro, abril, julho e outubro, que representam os meses centrais de verão, outono, inverno e primavera, respectivamente. Séries históricas de temperaturas mínimas e máximas do ar diárias, com extensão mínima de 30 anos, foram analisadas com base no teste de Mann-Kendall e no uso de regressão linear simples. As tendências foram consideradas significativas somente quando ambas as avaliações foram significativas; neste caso, determinaram-se as taxas de alteração das temperaturas. Houve boa concordância entre os testes de significância para a detecção de tendências nas séries históricas, na maioria dos municípios. Observou-se tendência de elevação das temperaturas mínimas em julho de até 1,5ºC por década, com tendências generalizadas de aumento na maior parte do estado, em outubro e janeiro, e também na escala anual. Exceções foram verificadas especialmente em municípios de maiores altitudes, em que as temperaturas mínimas diminuíram no inverno. Há predominância de municípios com tendência significativa de aumento de temperaturas, independentemente da escala de avaliação. Tendências de aumento nas temperaturas são esperadas mais comumente no sentido sul-norte do Estado de Minas Gerais.

  3. Diferentes tendências em pesquisas sobre a fala egocêntrica: análise de produções brasileiras

    Directory of Open Access Journals (Sweden)

    Alessandra de Morais

    2016-01-01

    pesquisas desenvolvidas no Brasil sobre a fala egocêntrica, de forma a identificar as principais questões teórico-metodológicas presentes em seu estudo. A busca foi feita no banco de Teses da CAPES e abarcou o período de 1987 a 2012; foram encontradas oito teses / dissertações. Os resultados demonstraram a abordagem predominante da fala egocêntrica à luz da perspectiva Histórico-Cultural, de Vigotski, com a presença, sobretudo, de duas tendências: estudos que confirmam seus postulados e os que sugerem contribuições de outros teóricos, em especial de Bakhtin. Uma terceira tendência foi também reconhecida, que, embora sinalize para os trabalhos de Piaget e Vigotski, tece críticas a ambos e não adere a nenhum deles.

  4. Tendências dos benefícios previdenciários por câncer bucal e de orofaringe de 2006 a 2013 no Brasil

    Directory of Open Access Journals (Sweden)

    Rafael Aiello Bomfim

    2018-02-01

    Full Text Available Resumo Objetivo: analisar as tendências de concessão de auxílios-doença previdenciários por câncer bucal e de orofaringe no período de 2006 a 2013, no Brasil. Métodos: estudo de séries temporais com dados dos trabalhadores segurados pelo Instituto Nacional de Seguridade Social (INSS; utilizaram-se regressões generalizadas lineares de Prais-Winstein para o cálculo da variação percentual anual (VPA. Resultados: os benefícios previdenciários por câncer de boca e de orofaringe mostraram tendência crescente (VPA=9,0%; IC95% 1,4;17,4; benefícios para outras partes da boca, nasofaringe, orofaringe, assoalho da boca e palato mostraram aumento significativo; comércio (5,5% e indústrias de transformação (5,2% foram as atividades mais prevalentes; evidenciaram-se altas proporções de campos ignorados nos sistemas de informações (média de 72,9%. Conclusão: as tendências dos benefícios ocupacionais por câncer de boca e de orofaringe mostraram crescimento significativo.

  5. Tendência temporal da mortalidade por homicídios na cidade de São Paulo, Brasil, 1979-1994

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    Rita Barradas Barata

    Full Text Available Estudou-se a tendência da mortalidade por homicídios segundo sexo e idade na cidade de São Paulo entre 1979 e 1994, utilizando modelos de ajuste de tendência temporal selecionados com base na significância de beta e valor de R², e análise de resíduos pela técnica de box and whisker plot. A mortalidade por homicídios em São Paulo passou de 12,2 óbitos por 100.000 hab. em 1979 para 34,2 em 1994, apresentando crescimento linear de 1,17 ao ano. O mesmo comportamento é observado em ambos os sexos, embora as taxas para os homens sejam cerca de 14 vezes maiores, denotando a deterioração das condições de vida urbana. Tanto os menores de dez anos como os maiores de 60 anos apresentam taxas constantes no período em valores relativamente baixos. O grupo de 10 a 19 anos apresenta crescimento das taxas segundo o modelo multiplicativo (incrementos 132,55. Os adultos jovens de 20 a 39 anos apresentam taxas crescentes durante todo o período, segundo o modelo linear, enquanto os adultos de 40 a 59 anos apresentam crescimento segundo o modelo recíproco. Observa-se, assim, que cada grupo de idade e sexo apresenta tendência temporal peculiar no período considerado.

  6. Tendências anuais e sazonais nos extremos de temperatura do ar e precipitação em campina grande - pb

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    Leydson Galvíncio Dantas

    2015-12-01

    Full Text Available RESUMO Devido à rápida expansão urbana e potencial turístico da região, o objetivo deste estudo foi a obtenção da distribuição temporal dos índices de extremos climáticos dependentes de dados diários de temperatura e precipitação, definido pela OMM, para o período de 1975 a 2011, e utilizando os testes estatísticos não paramétricos obter a magnitude das tendências dos referidos índices para a cidade de Campina Grande - PB. Os resultados mostram que as temperaturas mínimas e máxima diárias têm aumentado gradativamente ao longo das últimas décadas, apresentando tendências sazonais crescentes ao longo dos anos e que as temperaturas mínimas tiveram maior aumento. O número de dias e noites quentes por ano tem aumentado, proporcionando assim uma redução significativa dos dias e noites frias. Foi observado que as temperaturas mínimas e máximas apresentam maiores tendências de aumento nas estações do outono e primavera, respectivamente. Baseado nos índices extremos de precipitação, mesmo sem significância estatística, foi observado que as chuvas intensas tendem a aumentar, ocorrendo em um período menor de tempo.

  7. Tendências da hanseníase no Tocantins, um estado hiperendêmico do Norte do Brasil, 2001-2012

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    Lorena Dias Monteiro

    2015-05-01

    Full Text Available A hanseníase é hiperendêmica no Estado do Tocantins, Brasil. O objetivo do estudo foi analisar as tendências dos indicadores da hanseníase no Tocantins em 2001-2012. Análise de dados advindos do Sistema de Informação de Agravos de Notificação (SINAN. Incluíram-se casos novos de residentes no Tocantins. Calcularam-se os indicadores da hanseníase e analisaram-se as tendências temporais por meio de regressão polinomial. Houve tendência significativa e decrescente para a detecção geral (R2 = 0,40; p 0,05, detecção de casos com grau 2 de incapacidade física (R2 = 0,37; p > 0,05 e proporção de casos com grau 2 (R2 = 0,49; p > 0,05. Houve aumento significativo para a proporção de casos com grau 1 de incapacidade (R2 = 0,82; p < 0,05 e proporção de casos multibacilares (R2 = 0,81; p < 0,05. O Tocantins apresenta regiões com alta transmissão e diagnóstico tardio da hanseníase, apontando a expansão da doença de forma heterogênea na análise temporal.

  8. Adolescência e Tendência Antissocial: o Rap como Expressão de uma Privação Emocional

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    Cláudia Yaísa Gonçalves da Silva

    Full Text Available O presente estudo objetiva refletir sobre a tendência antissocial no adolescente/jovem, por meio da análise do conteúdo descrito nas letras de músicas de rap brasileiro, as quais em geral surgem carregadas de revolta, inconformismo, denúncias sociais e esperança. A pesquisa se caracteriza como exploratória, documental e qualitativa. Para tanto, foi realizada análise de conteúdo das letras, e posterior discussão embasada na teoria de Donald Woods Winnicott, buscando nos trechos das músicas indícios referentes a privações ambientais e o sentido que as letras carregam no contexto do comportamento antissocial. Na análise de conteúdo encontraram-se três categorias: a falha ambiental como princípio para a tendência antissocial, a tendência antissocial enquanto esperança de reparação, e o rappara além da música. Nos excertos das letras de rapselecionadas, os comportamentos antissociais mostraram-se enquanto saída emocional encontrada pelos adolescentes/jovens com histórico de privação, fazendo-os adotarem uma conduta desafiadora socialmente como forma de buscar uma contenção externa para reparar a falha vivenciada antes por alguma figura referencial. Conclui-se que o rap se instaurou como solução positiva para a expressão dos sentimentos e a conquista de uma identidade e reconhecimento social frente aos pares.

  9. Tendências temporais e espaciais da qualidade das águas superficiais da sub-bacia do Rio das Velhas, estado de Minas Gerais

    OpenAIRE

    Trindade, Ana Laura Cerqueira; Almeida, Katiane Cristina de Brito; Barbosa, Pedro Engler; Oliveira, Sílvia Maria Alves Corrêa

    2016-01-01

    RESUMO Este artigo apresenta uma análise da tendência temporal e espacial da qualidade das águas superficiais da sub-bacia do Rio das Velhas, inserida na bacia do Rio São Francisco, em Minas Gerais, Brasil. Foram analisados 16.625 dados coletados no período de 2002 a 2011 pelo programa de monitoramento de qualidade das águas superficiais efetuado pelo Instituto Mineiro de Gestão das Águas (Igam). Testes estatísticos, multivariados e não paramétricos foram utilizados para avaliar 11 variáveis ...

  10. Tendências de temperaturas mínimas e máximas do ar no Estado de Minas Gerais

    OpenAIRE

    Léo Fernandes Ávila; Carlos Rogério de Mello; Silvia de Nazaré Monteiro Yanagi; Olívio Bahia Sacramento Neto

    2014-01-01

    O objetivo deste trabalho foi avaliar tendências das temperaturas mínimas e máximas no Estado de Minas Gerais. Foram avaliados dados de 43 municípios, tendo-se considerado as escalas anual e sazonal - janeiro, abril, julho e outubro, que representam os meses centrais de verão, outono, inverno e primavera, respectivamente. Séries históricas de temperaturas mínimas e máximas do ar diárias, com extensão mínima de 30 anos, foram analisad...

  11. Consumo de bebidas alcoólicas na população adulta Brasileira: características sociodemográficas e tendência

    OpenAIRE

    Moura,Erly Catarina; Malta,Deborah Carvalho

    2011-01-01

    OBJETIVO: Estimar o consumo de bebidas alcoólicas, identificar as características sociodemográficas associadas a este consumo em 2006 e avaliar a tendência de consumo de 2006 a 2009. MÉTODOS: Foram avaliados, em 2006, 54.369 adultos residentes nas capitais de estados brasileiros e no Distrito Federal. Considerou-se consumo habitual a ingestão de qualquer quantidade de bebida alcoólica nos últimos 30 dias, e consumo abusivo a ingestão de mais de 5 doses para homens ou mais de 4 doses para mulh...

  12. « Pereira prétend » de Didier Bezace, une mise en scène synesthésique ou les parfums de la conscience

    OpenAIRE

    Duca, Eve

    2017-01-01

    Smell indeed is rarely stimulated on modern stages, but when it is, the staging is remembered all the more vividly since the memory of smell lasts longer than other memories. In adaptation of Pereira prétend, Didier Bezace produces odours which also stimulate tastes, such as lemon, sardines and cigars. This article studies the way the different senses are used in Bezace’s staging in order to understand their role, meaning and impact. The article focuses on Didier Bezace’s choice to utilize sm...

  13. Tendências observadas em indicadores de extremos climáticos de temperatura e precipitação no estado do Paraná

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    Wanderson Luiz Silva

    2015-06-01

    Full Text Available O presente trabalho faz uma análise das tendências de extremos climáticos baseada em indicadores calculados a partir de séries de dados observacionais diários de temperatura e de precipitação durante 35 anos em 20 estações meteorológicas do IAPAR, no Estado do Paraná. O objetivo é contribuir para estudos sobre avaliação de impactos e vulnerabilidade climática, requeridos para elaborar estratégias de adaptação às mudanças climáticas. Inicialmente as climatologias de temperatura do ar e de precipitação no Estado são revisitas. Com relação às tendências de extremos climáticos, os resultados dos indicadores associados à temperatura apontam para um padrão de aquecimento generalizado estatisticamente significativo em grande parte do Paraná. A porcentagem de dias e noites quentes no Estado aumentou consideravelmente a uma taxa de 0,1 a 0,4 %/ano entre 1976 e 2010. As médias anuais das temperaturas mínimas e máximas indicam uma elevação em quase todo o Paraná em torno de +0,02°C/ano no mesmo período. Os indicadores de temperatura mínima apresentam tendências de aumento mais significativas que os de temperatura máxima. Por outro lado, a maior parte dos indicadores de extremos climáticos associados à precipitação não apresenta significância estatística, com exceção de alguns poucos em distintas regiões do Estado. Destes, destacam-se apenas as tendências de elevação nos períodos secos (+0,25 mm/ano em Pato Branco e Planalto no sudoeste do Paraná e de redução das chuvas fortes (-0,5 mm/ano em Cambará, Ibiporã e Umuarama no norte do Estado.

  14. Empreendorismo no Brasil: situação e tendências DOI:10.5007/2175-8077.2011v13n29p133

    Directory of Open Access Journals (Sweden)

    Magali Geovana Ramlow Campelli

    2011-04-01

    Full Text Available Este artigo apresenta as tendências do empreendedorismo no Brasil. Neste trabalho são destacadas as iniciativas adotadas no País com enfoque para a avaliação dos resultados produzidos pelo programa Empretec e o desempenho apontado pelos relatórios do Global Entrepreneurship Monitor – GEM. Temas recentes também são introduzidos no cenário atual,  tais como,  o empreendedorismo social e o educacional.

  15. Tendências católicas: perspectivas do cristianismo da libertação Catholic tendencies: perspectives of the freedom cristianism

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    Flávio Munhoz Sofiati

    2009-04-01

    Full Text Available O texto analisa as diferentes vertentes da Igreja Católica no Brasil, apresentando-as a partir de teóricos da própria Igreja das ciências sociais. Em seguida, discute-se a tendência ligada à Teologia da Libertação, chamada de Cristianismo da Libertação. Afirma-se que o conceito de “Tendências Internas do Catolicismo” é mais apropriado para compreender os processos internos do catolicismo e que, atualmente, a Teologia da Libertação vem perdendo espaço no cenário religioso. Isso ocorre em virtude de questões internas – como o fortalecimento do movimento carismático – e externas – como o advento do neoliberalismo. Diante dessa situação, esse segmento assume uma nova postura de atuação, que tem como idéia central a construção de mudanças “de baixo para cima” e em longo prazo. Conclui-se que houve um recuo programático dessa tendência que passa a priorizar sua ação no interior da Igreja e a valorizar temas como espiritualidade, ecologia e cultura em detrimento da dimensão política. Palavras-chaves: Sociologia da Religião. Catolicismo. Tendências católicas. Teologia da libertação. The text analyzes different aspects of the Catholic Church in Brazil, presenting them through theories of the church, from social sciences. After that there is a discussion about the tendency connected to the Theory of Freedom, so called “Freedom Cristianism”. It is said that the concept of “Inner Theories of Catholicism” is more appropriate to understand the inner processes of the Catholicism and that, nowadays, the Freedom Theory has been loosing space inside the religious scenery. This occurs due to inner reasons – such as the growing strength of the charismatic movement – and also due to external reasons – as the ascending of Neoliberalism. With that, this segment gets to a new posture of action which has as central idea the“from down to up” changes, during long terms. After all, there is the

  16. Tendência das taxas de mortalidade infantil e de seus componentes em Guarulhos-SP, no período de 1996 a 2011

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    Daniel Hideki Bando

    Full Text Available OBJETIVO: analisar as tendências das taxas de mortalidade infantil (TMI e seus componentes em Guarulhos-SP, no período 1996-2011. MÉTODOS: regressão linear segmentada, para estimar as variações percentuais anuais (VPA. RESULTADOS: em 1996, a TMI e de seus componentes neonatal precoce, neonatal tardio e pós-neonatal foram, respectivamente, de 31,6, 16,7, 3,4 e 11,6 por 1000 nascidos vivos; em 2011, essas taxas foram de 12,6, 5,9, 1,6 e 5,1 respectivamente; houve diminuição significativa das TMI em todo o período; de 1996 a 2002, a VPA foi de -9,9, e de 2002 a 2011, foi de -3,7; o componente neonatal apresentou igual padrão; o componente neonatal precoce apresentou diminuição de 1996 a 2002 (VPA: -12,8, permanecendo estável até 2011; verificou-se diminuição do componente neonatal tardio de 1996 a 2009 (VPA: -2,8; o componente pós-neonatal apresentou redução em todo o período (VPA: -5,7. CONCLUSÃO: observou-se tendência de diminuição das TMI e de seus componentes.

  17. Análise da tendência da mortalidade masculina no Rio de Janeiro: contribuição da enfermagem

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    Elisabete Pimenta Araújo Paz

    2014-12-01

    Full Text Available Objetivo: Analisar a tendência de mortalidade entre homens no Município do Rio de Janeiro, por grupo de causas, entre 1996 e 2011. Métodos: Estudo descritivo de série temporal, utilizando dados de óbitos masculinos de residentes no Município do Rio de Janeiro, no período de 1996 a 2011, para grandes grupos de causas. Os dados foram analisados com os softwares Excel 2010 e Statistical Package for the Social Sciences (SPSS versão 22.0. Resultados: A tendência da mortalidade por grandes grupos de causas entre homens no Município do Rio de Janeiro está decrescendo, com diferença entre os grupos de causas. Porém, estes homens seguem adoecidos com o passar dos anos. Conclusão: A Política Nacional de Atenção à Saúde do Homem deve estar mais sensível a esta realidade, ofertando uma atenção em saúde capaz de reconhecer mais integralmente as necessidades de saúde desse público.

  18. Tendências de normalização na tradução para o inglês de as mulheres de Tijucopapo

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    Grace Gonçalves GRIGOLETO

    2011-07-01

    Full Text Available O presente artigo tem por objetivo analisar possíveis tendências de normalização por parte da tradutora Irene Matthews na tradução para o inglês da obra As mulheres de Tijucopapo, de Marilene Felinto. A metodologia situa-se no campo dos estudos da tradução baseados em corpus (proposta de BAKER, 1993, 1995, 1996, 2000; estudos sobre normalização de SCOTT, 1998; e pesquisas de CAMARGO, 2005, 2007, e no da linguística de corpus (estudos de BERBER SARDINHA, 2003, 2004. A pesquisa foi realizada por meio de uma combinação de análises semimanuais e de análises computadorizadas com o auxílio do programa WordSmith Tools. Com base em Scott (1998, examinamos a tradução de cinco vocábulos considerados preferenciais da autora, juntamente com seu cotexto, em relação a três características de normalização. Os resultados finais mostram que Matthews tende a usar estratégias que podem ser identificadas como características de normalização.

  19. Assessment of the dermal exposure to azoxystrobin among women tending cucumbers in selected Polish greenhouses after restricted entry intervals expired--the role of the protective gloves.

    Science.gov (United States)

    Jurewicz, Joanna; Hanke, Wojciech; Sobala, Wojciech; Ligocka, Danuta

    2009-01-01

    The purpose of our study was to determine the level of skin contamination by azoxystrobin in a group of women tending cucumbers in a vegetable-growing greenhouse after restricted entry intervals expired. Exposure samples were assessed on two days during the spring: first entry on the day after spraying of azoxystrobin and second entry six days later. Dermal exposure was measured by using patches on the outside of clothing and sampling gloves underneath regular working gloves. Pesticide deposited on clothing patches and gloves as a substitute for skin deposition was determined by liquid chromatography and mass spectrometry (LC-MS/MS). The study has shown that workers in a Polish greenhouse are exposed to pesticides at re-entry into the greenhouse after pesticides were sprayed several days earlier. Azoxystrobin has been detected on hands, shoulders and chest. Higher levels of azoxystrobin were found on the cotton gloves of women tending the vegetables than on the patches. The levels decreased (by about 60%) on the patches and increased (by about 250%) on the cotton gloves between the two days of measurement. Women working in a vegetable-growing greenhouse and not directly engaged in the process of spraying experience a measurable dermal exposure to azoxystrobin. The protective gloves constitute a source of secondary exposure rather than protecting employees' hands from contact with the pesticide. More efficient personal protective gloves for proper protection of women working in vegetable greenhouses are needed.

  20. CRUZEIROS MARÍTIMOS: tendência da demanda no mercado brasileiro e internacional para os próximos 5 anos, a partir de 2016

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    Carlos Eduardo de Almeida Ramoa

    2017-06-01

    Full Text Available Ao contrário do que vem ocorrendo no mercado internacional, o turismo marítimo no Brasil tem apresentado queda na taxa de crescimento desde 2011. Este artigo tem por objetivo verificar as perspectivas do mercado brasileiro e mundial por cruzeiros marítimos para os próximos cinco anos a partir de 2016. Para isso foi realizado um estudo de caráter exploratório e descritivo de forma a analisar históricos da oferta e demanda, de 2006 a 2015. Utilizou-se o método de procedimento estatístico e funções estatísticas de regressão para se obter a projeção da tendência futura. Os resultados apresentados indicam que, se fosse mantida a tendência verificada até 2010, a perspectiva da demanda no Brasil seria de crescimento, como vem ocorrendo no mercado internacional.

  1. A phase I study of vaccination with NY-ESO-1f peptide mixed with Picibanil OK-432 and Montanide ISA-51 in patients with cancers expressing the NY-ESO-1 antigen.

    Science.gov (United States)

    Kakimi, Kazuhiro; Isobe, Midori; Uenaka, Akiko; Wada, Hisashi; Sato, Eiichi; Doki, Yuichiro; Nakajima, Jun; Seto, Yasuyuki; Yamatsuji, Tomoki; Naomoto, Yoshio; Shiraishi, Kenshiro; Takigawa, Nagio; Kiura, Katsuyuki; Tsuji, Kazuhide; Iwatsuki, Keiji; Oka, Mikio; Pan, Linda; Hoffman, Eric W; Old, Lloyd J; Nakayama, Eiichi

    2011-12-15

    We conducted a phase I clinical trial of a cancer vaccine using a 20-mer NY-ESO-1f peptide (NY-ESO-1 91-110) that includes multiple epitopes recognized by antibodies, and CD4 and CD8 T cells. Ten patients were immunized with 600 μg of NY-ESO-1f peptide mixed with 0.2 KE Picibanil OK-432 and 1.25 ml Montanide ISA-51. Primary end points of the study were safety and immune response. Subcutaneous injection of the NY-ESO-1f peptide vaccine was well tolerated. Vaccine-related adverse events observed were fever (Grade 1), injection-site reaction (Grade 1 or 2) and induration (Grade 2). Vaccination with the NY-ESO-1f peptide resulted in an increase or induction of NY-ESO-1 antibody responses in nine of ten patients. The sera reacted with recombinant NY-ESO-1 whole protein as well as the NY-ESO-1f peptide. An increase in CD4 and CD8 T cell responses was observed in nine of ten patients. Vaccine-induced CD4 and CD8 T cells responded to NY-ESO-1 91-108 in all patients with various HLA types with a less frequent response to neighboring peptides. The findings indicate that the 20-mer NY-ESO-1f peptide includes multiple epitopes recognized by CD4 and CD8 T cells with distinct specificity. Of ten patients, two with lung cancer and one with esophageal cancer showed stable disease. Our study shows that the NY-ESO-1f peptide vaccine was well tolerated and elicited humoral, CD4 and CD8 T cell responses in immunized patients. Copyright © 2011 UICC.

  2. Interest rate derivatives

    DEFF Research Database (Denmark)

    Svenstrup, Mikkel

    This Ph.D. thesis consists of four self-contained essays on valuation of interest rate derivatives. In particular derivatives related to management of interest rate risk care are considered.......This Ph.D. thesis consists of four self-contained essays on valuation of interest rate derivatives. In particular derivatives related to management of interest rate risk care are considered....

  3. Tendência da epidemia de casos de aids no Sul do Brasil no período de 1986 a 2008

    Directory of Open Access Journals (Sweden)

    Flaviane Mello Lazarini

    2012-12-01

    Full Text Available OBJETIVO: Descrever a tendência dos casos de aids por sexo e faixa etária de 1986 a 2008. MÉTODOS: Foi analisada a tendência da aids por faixa etária e por sexo, em Londrina, PR, em dois períodos: 1986-1995 e 1996-2008. Dentre os modelos polinomiais, o de primeiro grau explicou melhor a tendência da epidemia da aids nos dois períodos. Foram calculadas as taxas de incidência para homens que fazem sexo com homens (HSH, usuários de drogas injetáveis (UDI, homens heterossexuais e mulheres. RESULTADOS: No primeiro período, de 1986 a 1995, houve incremento das taxas de incidência em quase todas as faixas etárias e crescimento da epidemia em ambos os sexos (p < 0,001, mais acentuado em homens de 14 a 39 anos. O segundo período (1996-2008 não apresentou incremento estatístico positivo ou negativo, indicando estabilização da epidemia. Verificou-se que ocorreu queda significativa na faixa de 14 a 29 anos no sexo masculino, com incremento de 0,88 no primeiro período e 0,87 no segundo. Mulheres de 50 anos e mais apresentaram aumento significativo (p = 0,019. Os grupos UDI e HSH predominaram como categorias de exposição e HSH ultrapassou UDI no último triênio do estudo. A partir de 2000, a taxa de incidência entre mulheres de 15 a 49 anos superou a de homens heterossexuais. CONCLUSÕES: Houve queda nas taxas de incidência nas faixas etárias mais jovens e estabilização nas demais idades. O aumento da proporção de mulheres e do predomínio de HSH entre as categorias de exposição aponta para necessidade de estratégias diferenciadas para atingir grupos com características diversas.

  4. Tendências temporais e espaciais da qualidade das águas superficiais da sub-bacia do Rio das Velhas, estado de Minas Gerais

    Directory of Open Access Journals (Sweden)

    Ana Laura Cerqueira Trindade

    Full Text Available RESUMO Este artigo apresenta uma análise da tendência temporal e espacial da qualidade das águas superficiais da sub-bacia do Rio das Velhas, inserida na bacia do Rio São Francisco, em Minas Gerais, Brasil. Foram analisados 16.625 dados coletados no período de 2002 a 2011 pelo programa de monitoramento de qualidade das águas superficiais efetuado pelo Instituto Mineiro de Gestão das Águas (Igam. Testes estatísticos, multivariados e não paramétricos foram utilizados para avaliar 11 variáveis físicas, químicas e microbiológicas de 29 estações de monitoramento. Os resultados das análises de tendência Mann-Kendall/Sazonal de Mann-Kendall sugeriram que a maioria dos cursos d'água da região apresentam valores estáveis das variáveis ao longo do período estudado, com maiores alterações associadas a coliformes termotolerantes, demanda bioquímica de oxigênio (DBO, nitrato e índice de qualidade das águas (IQA, principalmente nas proximidades dos grandes centros urbanos. A análise de Cluster definiu três grandes grupos de estações de monitoramento, agrupadas segundo a qualidade de suas águas, correspondentes aos níveis de alta poluição, poluição moderada e baixa poluição. No entanto, ao longo de toda a sub-bacia, foi observada a degradação da qualidade da água durante o período estudado, principalmente relacionada ao lançamento de esgotos domésticos. Uma importante constatação foi a alteração da qualidade da água no baixo Rio das Velhas, apontada pela tendência de redução do IQA em estações localizadas nessa região, o que merece atenção dos órgãos governamentais para ações de manejo.

  5. Tendências temporais e espaciais da qualidade das águas superficiais da sub-bacia do Rio das Velhas, estado de Minas Gerais

    Directory of Open Access Journals (Sweden)

    Ana Laura Cerqueira Trindade

    2016-10-01

    Full Text Available RESUMO Este artigo apresenta uma análise da tendência temporal e espacial da qualidade das águas superficiais da sub-bacia do Rio das Velhas, inserida na bacia do Rio São Francisco, em Minas Gerais, Brasil. Foram analisados 16.625 dados coletados no período de 2002 a 2011 pelo programa de monitoramento de qualidade das águas superficiais efetuado pelo Instituto Mineiro de Gestão das Águas (Igam. Testes estatísticos, multivariados e não paramétricos foram utilizados para avaliar 11 variáveis físicas, químicas e microbiológicas de 29 estações de monitoramento. Os resultados das análises de tendência Mann-Kendall/Sazonal de Mann-Kendall sugeriram que a maioria dos cursos d'água da região apresentam valores estáveis das variáveis ao longo do período estudado, com maiores alterações associadas a coliformes termotolerantes, demanda bioquímica de oxigênio (DBO, nitrato e índice de qualidade das águas (IQA, principalmente nas proximidades dos grandes centros urbanos. A análise de Cluster definiu três grandes grupos de estações de monitoramento, agrupadas segundo a qualidade de suas águas, correspondentes aos níveis de alta poluição, poluição moderada e baixa poluição. No entanto, ao longo de toda a sub-bacia, foi observada a degradação da qualidade da água durante o período estudado, principalmente relacionada ao lançamento de esgotos domésticos. Uma importante constatação foi a alteração da qualidade da água no baixo Rio das Velhas, apontada pela tendência de redução do IQA em estações localizadas nessa região, o que merece atenção dos órgãos governamentais para ações de manejo.

  6. Tendências de temperaturas mínimas e máximas do ar no Estado de Minas Gerais

    OpenAIRE

    Ávila, Léo Fernandes; Mello, Carlos Rogério de; Yanagi, Silvia de Nazaré Monteiro; Sacramento Neto, Olívio Bahia

    2014-01-01

    O objetivo deste trabalho foi avaliar tendências das temperaturas mínimas e máximas no Estado de Minas Gerais. Foram avaliados dados de 43 municípios, tendo-se considerado as escalas anual e sazonal - janeiro, abril, julho e outubro, que representam os meses centrais de verão, outono, inverno e primavera, respectivamente. Séries históricas de temperaturas mínimas e máximas do ar diárias, com extensão mínima de 30 anos, foram analisadas com base no teste de Mann-Kendall e no uso de regressão l...

  7. Tendências da literatura científica sobre genética de populações de plantas do Cerrado

    OpenAIRE

    Souza,Ueric José Borges de; Telles,Mariana Pires de Campos; Diniz-Filho,José Alexandre Felizola

    2016-01-01

    RESUMO O Cerrado é considerado um dos "hotspots" mundiais de biodiversidade, em função da grande extensão de vegetação natural que vem sendo continuamente perdida e do elevado número de espécies endêmicas de plantas, que muitas vezes têm sido listadas como prioridades em programas de conservação e para estudos de genética de populações. A fim de verificar tendências nos estudos de genética de populações das espécies de plantas deste bioma, uma avaliação cienciométrica dos artigos publicados e...

  8. Caracterização Climatológica e Tendências Observadas em Extremos Climáticos no Estado do Rio de Janeiro

    Directory of Open Access Journals (Sweden)

    Wanderson Luiz Silva

    2014-07-01

    Full Text Available Neste trabalho elabora-se uma climatologia da temperatura do ar e da precipitação e uma análise das tendências nos extremos climáticos de tais variáveis para o estado do Rio de Janeiro, a partir de dados observacionais entre 1961 e 2012. Os resultados da climatologia mostram temperaturas mínimas médias oscilando entre 9,5 e 11°C (15,5 e 17°C no inverno (verão na região Serrana. Valores mais elevados ocorrem principalmente no litoral, onde as médias de temperatura mínima variam entre 17 e 18,5°C (21,5 e 23°C no inverno (verão. As menores temperaturas máximas médias oscilam entre 21,5 e 23°C (26 e 27,5°C no inverno (verão na região Serrana e os valores mais elevados encontram-se na região Metropolitana e no Norte/Noroeste Fluminense, oscilando entre 26 e 27,5°C (32 e 33,5°C no inverno (verão. A precipitação anual apresenta máximos em áreas elevadas (cerca de 2500 a 2800 mm ao ano e mínimos sobre as regiões de baixada e de costa (entre 700 e 1300 mm ao ano. Para as tendências observadas nos extremos climáticos de temperatura, a região Metropolitana e a região Norte e Noroeste do estado apontam para aumentos estatisticamente significativos da temperatura máxima média (entre +0,01 e +0,08°C/ano. Notam-se também tendências estatisticamente significativas de elevação na porcentagem de noites e de dias quentes em quase todo o estado (entre +0,1 e +0,6 %dias/ano. Quanto à chuva, observa-se que há uma tendência estatisticamente significativa de aumento dos totais pluviométricos anuais nas Baixadas Litorâneas (entre +4,0 e +32,0 mm/ano. Também verifica-se uma elevação significativa dos totais pluviométricos das chuvas mais fortes do ano nas Baixadas Litorâneas e em parte da região Metropolitana, com magnitudes entre +2,0 e +20,0 mm/ano.

  9. Tendências de tradução de mexicanismos em roteiros e episódios das séries televisivas Chaves e Chapolin

    OpenAIRE

    Santos, Orlanda Miranda

    2013-01-01

    Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Programa de Pós-Graduação em Estudos da Tradução, Florianópolis, 2013. Esta pesquisa, por um lado, teve o objetivo de identificar tendências de tradução de mexicanismos em roteiros das séries Chaves e Chapolin, criadas na década de 70, no México, exibidas pela rede Televisa, traduções essas feitas por acadêmicos de Letras Espanhol. Teve por fim analisar episódios retraduzidos pela equipe de dublag...

  10. Tendências das séries históricas do índice de calor no município de Santa Maria - RS

    Directory of Open Access Journals (Sweden)

    Stefanía Dalmolin da Silva

    2014-01-01

    Full Text Available Este trabalho teve como objetivo calcular e analisar as séries históricas mensais do Índice de Calor (IC para Santa Maria, RS, Brasil, no período de 1968 a 2011. As variáveis meteorológicas utilizadas neste trabalho foram pressão atmosférica, temperatura do bulbo seco e temperatura do bulbo úmido, no horário das 9h (12UTC, 15h (18UTC e 21h (00UTC. Foi realizada análise de tendência das séries históricas para o valor absoluto e a média mensais do IC através do teste de Mann-Kendall e análise de regressão linear simples para quantificar a tendência, com nível de significância de 95% (α=0,05. Para o valor máximo, no horário das 15h (18UTC, as séries históricas para os meses de janeiro e abril apresentaram acréscimo no valor do índice de calor na magnitude de 0,76°C década-1 e 0,92°C década-1, respectivamente. No horário das 21h (00 UTC, os meses de abril e novembro apresentaram aumento de 0,43°C década-1 e 0,55°C década-1, respectivamente. Porém os meses de maio e agosto apresentaram diminuição de 0,69°C década-1 e 0,31°C década-1, respectivamente.

  11. Insights into the 3D architecture of an active caldera ring-fault at Tendürek volcano through modeling of geodetic data

    KAUST Repository

    Vasyura-Bathke, Hannes

    2015-04-28

    The three-dimensional assessment of ring-fault geometries and kinematics at active caldera volcanoes is typically limited by sparse field, geodetic or seismological data, or by only partial ring-fault rupture or slip. Here we use a novel combination of spatially dense InSAR time-series data, numerical models and sand-box experiments to determine the three-dimensional geometry and kinematics of a sub-surface ring-fault at Tendürek volcano in Turkey. The InSAR data reveal that the area within the ring-fault not only subsides, but also shows substantial westward-directed lateral movement. The models and experiments explain this as a consequence of a ‘sliding-trapdoor’ ring-fault architecture that is mostly composed of outward-inclined reverse segments, most markedly so on the volcano\\'s western flanks but includes inward-inclined normal segments on its eastern flanks. Furthermore, the model ring-fault exhibits dextral and sinistral strike-slip components that are roughly bilaterally distributed onto its northern and southern segments, respectively. Our more complex numerical model describes the deformation at Tendürek better than an analytical solution for a single rectangular dislocation in a half-space. Comparison to ring-faults defined at Glen Coe, Fernandina and Bárðarbunga calderas suggests that ‘sliding-trapdoor’ ring-fault geometries may be common in nature and should therefore be considered in geological and geophysical interpretations of ring-faults at different scales worldwide.

  12. Forests tend to cool the land surface in the temperate zone: An analysis of the mechanisms controlling radiometric surface temperature change in managed temperate ecosystems

    Science.gov (United States)

    Stoy, P. C.; Katul, G. G.; Juang, J.; Siqueira, M. B.; Novick, K. A.; Essery, R.; Dore, S.; Kolb, T. E.; Montes-Helu, M. C.; Scott, R. L.

    2010-12-01

    Vegetation is an important control on the surface energy balance and thereby surface temperature. Boreal forests and arctic shrubs are thought to warm the land surface by absorbing more radiation than the vegetation they replace. The surface temperatures of tropical forests tend to be cooler than deforested landscapes due to enhanced evapotranspiration. The effects of reforestation on surface temperature change in the temperate zone is less-certain, but recent modeling efforts suggest forests have a global warming effect. We quantified the mechanisms driving radiometric surface changes following landcover changes using paired ecosystem case studies from the Ameriflux database with energy balance models of varying complexity. Results confirm previous findings that deciduous and coniferous forests in the southeastern U.S. are ca. 1 °C cooler than an adjacent field on an annual basis because aerodynamic/ecophysiological cooling of 2-3 °C outweighs an albedo-related warming of stand-replacing ponderosa pine fire was ca. 1 °C warmer than unburned stands because a 1.5 °C aerodynamic warming offset a slight surface cooling due to greater albedo and soil heat flux. An ecosystem dominated by mesquite shrub encroachment was nearly 2 °C warmer than a native grassland ecosystem as aerodynamic and albedo-related warming outweighed a small cooling effect due to changes in soil heat flux. The forested ecosystems in these case studies are documented to have higher carbon uptake than the non-forested systems. Results suggest that temperate forests tend to cool the land surface and suggest that previous model-based findings that forests warm the Earth’s surface globally should be reconsidered.Changes to radiometric surface temperature (K) following changes in vegetation using paired ecosystem case studies C4 grassland and shrub ecosystem surface temperatures were adjusted for differences in air temperature across sites.

  13. ISA for the internet of tactical things

    Science.gov (United States)

    Moulton, Christine L.; Harrell, John M.; Hepp, Jared J.

    2017-05-01

    The Internet of Things (IoT) integrates a variety of different devices that provide more information than can currently be easily handled. While there is much good there are also many problems in the IoT world and not all of the potential solutions can be used in the unique environment of the military. The tactical edge of the military is an even harsher environment with both constrained communications and resources but still having requirements to process data in real time for improved command decisions.

  14. 1399-IJBCS-Article-Mohamed Isa

    African Journals Online (AJOL)

    USER

    SHESTCO), Abuja, Nigeria. *Corresponding author ... Chitin was synthesized from Nigerian brown shrimps by a chemical process involving demineralization and deproteinisation. ... biomedical, biocatalysis and waste water treatment processes (Li ...

  15. Tabagismo em estudantes de Medicina: tendências temporais e fatores associados Smoking among medical students: temporal trends and related variables

    Directory of Open Access Journals (Sweden)

    Ana Maria Baptista Menezes

    2004-06-01

    Full Text Available INTRODUÇÃO: Após o declínio observado na prevalência de tabagismo entre estudantes de Medicina entre as décadas de 1960 e 1980, parece estar ocorrendo, atualmente, uma estabilização nessa prevalência. OBJETIVO: Avaliar as tendências temporais de tabagismo entre estudantes de Medicina da Universidade Federal de Pelotas (RS nos últimos dezessete anos, e alguns dos fatores associados ao hábito de fumar desses estudantes. MÉTODO: Estudos transversais com metodologias comparáveis foram conduzidos em 1986, 1991, 1996 e 2002. Questionários auto-aplicáveis foram utilizados. Definiu-se como fumante o indivíduo que fumava mais de um cigarro por dia há mais de um mês. Foram realizadas análises descritivas iniciais, análises brutas com utilização dos testes de qui-quadrado para heterogeneidade e tendência linear, e regressão de Poisson para avaliar o efeito do ano cursado sobre a freqüência de tabagismo, com controle para a idade do estudante. RESULTADOS: A prevalência atual de tabagismo entre os estudantes foi de 10,1%, valor estatisticamente similar ao dos levantamentos de 1991 e 1996. Não foram encontradas diferenças na prevalência de tabagismo por sexo, idade, tabagismo materno ou paterno. A freqüência de tabagismo aumentou durante a faculdade. CONCLUSÕES: A tendência de declínio na prevalência de tabagismo em estudantes de Medicina da Universidade Federal de Pelotas parece estar sendo substituída por uma estabilização em torno de 10% a 15%. O combate ao fumo ainda parece indispensável em ambientes universitários, especialmente nas escolas de Medicina.BACKGROUND: Although the prevalence of smoking among medical students declined steadily between the 1960s and 1980s, it seems to have stabilized in recent years. OBJECTIVES: To evaluate temporal trends, over the last 17 years, in the smoking habits of medical students at the Universidade Federal de Pelotas, in the state of Rio Grande do Sul, Brazil, and to identify

  16. Vaccine Adjuvants in Fish Vaccines Make a Difference: Comparing Three Adjuvants (Montanide ISA763A Oil, CpG/Poly I:C Combo and VHSV Glycoprotein Alone or in Combination Formulated with an Inactivated Whole Salmonid Alphavirus Antigen

    Directory of Open Access Journals (Sweden)

    Hanna L. Thim

    2014-03-01

    Full Text Available Most commercial vaccines offered to the aquaculture industry include inactivated antigens (Ag formulated in oil adjuvants. Safety concerns are related to the use of oil adjuvants in multivalent vaccines for fish, since adverse side effects (e.g., adhesions can appear. Therefore, there is a request for vaccine formulations for which protection will be maintained or improved, while the risk of side effects is reduced. Here, by using an inactivated salmonid alphavirus (SAV as the test Ag, the combined use of two Toll-like receptor (TLR ligand adjuvants, CpG oligonucleotides (ODNs and poly I:C, as well as a genetic adjuvant consisting of a DNA plasmid vector expressing the viral haemorrhagic septicaemia virus (VHSV glycoprotein (G was explored. VHSV-G DNA vaccine was intramuscularly injected in combination with intraperitoneal injection of either SAV Ag alone or combined with the oil adjuvant, Montanide ISA763, or the CpG/polyI:C combo. Adjuvant formulations were evaluated for their ability to boost immune responses and induce protection against SAV in Atlantic salmon, following cohabitation challenge. It was observed that CpG/polyI:C-based formulations generated the highest neutralizing antibody titres (nAbs before challenge, which endured post challenge. nAb responses for VHSV G-DNA- and oil-adjuvanted formulations were marginal compared to the CpG/poly I:C treatment. Interestingly, heat-inactivated sera showed reduced nAb titres compared to their non-heated counterparts, which suggests a role of complement-mediated neutralization against SAV. Consistently elevated levels of innate antiviral immune genes in the CpG/polyI:C injected groups suggested a role of IFN-mediated responses. Co-delivery of the VHSV-G DNA construct with either CpG/polyI:C or oil-adjuvanted SAV vaccine generated higher CD4 responses in head kidney at 48 h compared to injection of this vector or SAV Ag alone. The results demonstrate that a combination of pattern recognizing

  17. Tending Transformation Technology of Low-yielding Camellia reticulata in Tengchong%腾冲红花油茶低产林抚育改造技术

    Institute of Scientific and Technical Information of China (English)

    杨开保; 黄佳聪; 辛成莲; 万晓军

    2012-01-01

    Tending transformation test was conducted on 28hm 39 year old direct seeding forestation and long-term management absent low yielding Camellia reticulata in Tengchong. Through years of experimental research, we have come up with the forest garden governance, density adjustment, treelike adjustment; strengthen soil and water management and pest control tending transformation technologies. Four years after the transformation, the forest quality has greatly improved, tree vigor has recovered, substantial increases have been seen in harvests, and preharvest fruit drops have been contained. The average ripening rate has grown from 19. 93% to 41. 07% ; crude oil yield has risen up to 220. 5kg/hm2, equivalent to 9. 19 times the amount of 24kg/hm2 produced before, and 1. 77 times the amount of 124. 5kg/hm2 for pests and diseases control test. The test results have contributed technical support to the low-yielding Camellia reticulata transformation in Tengchong, the sustainable development of the industry in the old-production area and the improvement of Camellia reticulata yield and quality.%对面积28 hm2、树龄39 a、直播造林且长期失管的腾冲红花油荼低产林开展抚育改造试验.通过多年的试验研究,摸索出林相林园治理、密度调整、树型调整、加强土肥水管理及病虫害防治等抚育改造综合技术.改造后第四年的林分质量明显改善,树势恢复,大幅增产,采前落果得到根本遏制;植株平均结实率由19.93%增加到41.07%,粗油产量达220.5 kg/hm2,为改造前24 kg/hm2的9.19倍,为病虫害试验对照产量124.5 kg/hm2的1.77倍.试验结果为腾冲红花油荼低产林抚育改造,老产区巩固产业持续发展,提高油茶产量和品质提供了技术支特.

  18. Tuberculose refratária disseminada com acometimento do tendão bicipital em paciente imunocompetente Disseminated refractary tuberculosis with biceps tendon involvement in an immunocompetent patient

    Directory of Open Access Journals (Sweden)

    Marcelo dos Reis Oliveira

    2009-06-01

    Full Text Available OBJETIVO: Relatar um caso raro de tuberculose disseminada em paciente imunocompetente, que evoluiu, durante o tratamento medicamentoso padrão, com envolvimento do tendão da porção longa do bíceps e da articulação do ombro. MÉTODOS: À primeira avaliação, o diagnóstico correto não foi feito e o paciente foi tratado com fisioterapia para tendinopatia do manguito rotador. Entretanto, apresentou rápida formação de massa na região anterior do terço proximal do braço e piora da dor. A punção da massa revelou líquido amarelado, cuja análise laboratorial confirmou tratar-se de infecção por M. tuberculosis. RESULTADOS: O paciente foi tratado com desbridamento cirúrgico e troca do esquema medicamentoso e evoluiu com resolução do quadro infeccioso e melhora completa da função do ombro direito. CONCLUSÃO: Devido a sua alta prevalência no Brasil, a tuberculose deve sempre ser considerada no diagnóstico diferencial dos casos de comprometimento crônico e progressivo das articulações, ossos, músculos, tendões e bursas, mesmo em indivíduos imunocompetentes.OBJECTIVE: The authors report a rare case of disseminated tuberculosis which had compromised the long head of biceps tendon and shoulder joint, during standard drug therapy. METHODS: On a first sight, the accurate diagnosis wasn't accomplished and the patient had been treated with physiotherapy for rotator cuff tear. However, the patient presented with a fast growing mass in anterior region of the proximal third of the arm, complaining of pain increase. Aspirative punction of the mass revealed a yellow fluid and the laboratorial analysis confirmed infection by M. Tuberculosis. The patient was treated with surgical debridement and his drug therapy was changed. RESULTS: Resolution of infectious status and complete shoulder function restoration was succeeded. CONCLUSION: Due to its high prevalence in Brazil, tuberculosis must always be considered as a possible cause of

  19. Derivatives in emerging markets

    OpenAIRE

    Dubravko Mihaljek; Frank Packer

    2010-01-01

    Turnover of derivatives has grown more rapidly in emerging markets than in developed countries. Foreign exchange derivatives are the most commonly traded of all risk categories, with increasingly frequent turnover in emerging market currencies and a growing share of cross-border transactions. As the global reach of the financial centres in emerging Asia has expanded, the offshore trading of many emerging market currency derivatives has risen as well. Growth in derivatives turnover is positive...

  20. Perfil e tendências da liderança em uma empresa brasileira líder mundial de mercado

    Directory of Open Access Journals (Sweden)

    Marco Aurélio de Oliveira

    2015-06-01

    Full Text Available O objetivo deste trabalho é o entendimento de como a liderança ocorre em uma empresa brasileira líder mundial em seu mercado de atuação, em tempos marcados por grandes incertezas, particularmente nos dias atuais. Trata-se de uma pesquisa qualitativa, orientada pelo paradigma interpretativo, que busca, a partir dos dados colhidos em entrevistas com informantes, descrições detalhadas e interpretações para o fenômeno da liderança na organização em estudo. O ambiente onde a pesquisa foi desenvolvida é uma área de pesquisa e desenvolvimento de uma empresa brasileira líder mundial no seu mercado de atuação. Os tipos de liderança considerados foram a transacional e a transformacional. No presente trabalho também são discutidos aspectos relacionados com a tendência de evolução e posicionamento dessa liderança em termos de um cenário globalizado.

  1. As tendências pedagógicas e a prática educativa nas ciências da saúde

    Directory of Open Access Journals (Sweden)

    Pereira Adriana Lenho de Figueiredo

    2003-01-01

    Full Text Available As práticas educativas são amplamente utilizadas na área da saúde, tanto na formação contínua dos profissionais que atuam nesta área quanto no campo da educação em saúde para a população em geral. A interseção destes dois campos de conhecimento humano se dá através do desenvolvimento de práticas educativas norteadas por um conjunto de representações de homem e de sociedade que se quer efetivar. Essas representações são demonstradas através da discussão dos processos de ensino-aprendizagem utilizados nas tendências pedagógicas mais dominantes em nosso meio: a pedagogia tradicional, renovada, por condicionamento e a libertadora. A partir dos princípios, métodos e conseqüências ao nível individual e social de cada pedagogia apresentada, concluímos que a pedagogia libertadora pode produzir melhores resultados que as demais correntes pedagógicas estudadas, por possibilitar a participação ativa do educando no processo da aprendizagem, propiciando o desenvolvimento contínuo das habilidades humanas tanto da clientela quanto dos trabalhadores da área de saúde.

  2. As tendências pedagógicas e a prática educativa nas ciências da saúde

    Directory of Open Access Journals (Sweden)

    Adriana Lenho de Figueiredo Pereira

    Full Text Available As práticas educativas são amplamente utilizadas na área da saúde, tanto na formação contínua dos profissionais que atuam nesta área quanto no campo da educação em saúde para a população em geral. A interseção destes dois campos de conhecimento humano se dá através do desenvolvimento de práticas educativas norteadas por um conjunto de representações de homem e de sociedade que se quer efetivar. Essas representações são demonstradas através da discussão dos processos de ensino-aprendizagem utilizados nas tendências pedagógicas mais dominantes em nosso meio: a pedagogia tradicional, renovada, por condicionamento e a libertadora. A partir dos princípios, métodos e conseqüências ao nível individual e social de cada pedagogia apresentada, concluímos que a pedagogia libertadora pode produzir melhores resultados que as demais correntes pedagógicas estudadas, por possibilitar a participação ativa do educando no processo da aprendizagem, propiciando o desenvolvimento contínuo das habilidades humanas tanto da clientela quanto dos trabalhadores da área de saúde.

  3. O núcleo da inflação como a tendência comum dos preços

    Directory of Open Access Journals (Sweden)

    Fiorencio Antonio

    2002-01-01

    Full Text Available Nos últimos anos, diversos bancos centrais adotaram o regime de metas de inflação, dando início a um intenso debate sobre que medida de inflação adotar. Esse debate reflete a suspeita de que os índices de inflação tradicionais possam ser excessivamente ''nervosos'', no sentido de não discriminar entre choques de preços generalizados e idiossincráticos e entre choques permanentes e temporários. Este artigo define uma medida de núcleo de inflação - core inflation - como a tendência comum dos preços em um modelo dinâmico multivariado que, por construção, filtra choques transitórios e idiossincráticos e antecipa o nível futuro da inflação. O artigo mostra que o conhecido estimador de médias truncadas para o núcleo da inflação pode ser visto como uma proxy para o estimador de mínimos quadrados generalizados para dados heteroscedásticos. Foi utilizada uma média truncada assimétrica suavizada e obtida uma medida para o núcleo da inflação não condicional aos parâmetros do modelo.

  4. Tendências dos estudos com idosos mais velhos na comunidade: uma revisão sistemática (internacional

    Directory of Open Access Journals (Sweden)

    Idiane Rosset

    2011-03-01

    Full Text Available O estudo objetivou identificar e analisar as tendências e tipos de estudos, publicados no país e no exterior, envolvendo idosos >80 anos residentes na comunidade. Realizou-se uma revisão sistemática da literatura nacional nas bases de dados LILACS e SciELO e internacional nas bases PUBMED e EMBASE, nas duas últimas décadas. Selecionaram-se 162 referências internacionais e 12 nacionais. Predominou a área das ciências biológicas, tanto no nível nacional (50% quanto internacional (74,1%. Todos os trabalhos nacionais foram observacionais, sendo 91,7% de estudos transversais. Dentre os internacionais, 93,3% foram observacionais. Destes, 48,1% de estudos transversais e 37,6% de estudos de corte. Os Estados Unidos foram responsáveis por 41,4% do total de publicações internacionais. O Brasil e a China foram os únicos países em desenvolvimento a apresentar produções internacionais. Apesar do significativo aumento no número de produções científicas internacionais a partir de 2005, o mesmo ainda não foi constatado em nível nacional.

  5. Tempos anormais e novas fantasias. Novas tendências em direitos humanos, justiça e educação

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    Carlos Vilar Estêvão

    2015-01-01

    Full Text Available After characterizing the current times as abnormal times, with the creation, by the ideology of the market, of new fantasies that promise heaven on earth in terms of well-being, personal fulfillment and justice, the author makes an incursion in the land of human rights, justice, education and school, in order to unveil new interpretations, new myths, new abnormalities that are emerging within it, congruent with the market, understood as metonymy of global capitalism. In this view, rights are seen from a "multiuse" perspective, which makes them "malleable" at will and at the demands of the dominant rationality of the economy; likewise, justice tends to be construed from an individualistic and efficiency perspective, that is, as a factor that effectively contributes to the balance of trade and for maintaining the evenness of the social balance. Finally, education should constitute a sub-sector of the economy, with a functionalist format at the service of social and economic needs that come from the mercantile world.

  6. A tendência de conclusão dos acordos em forma simplificada: evolução e prática brasileira

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    Paula Wojcikiewicz Almeida

    2013-03-01

    Full Text Available A previsão de controle do poder legislativo, como exigência da sociedade democrática, constituiu regra geral nos textos constitucionais que efetuam a repartição de competências entre o poder executivo e legislativo em matéria de conclusão de tratados internacionais. Entretanto, a evolução das necessidades da sociedade contemporânea fez surgir uma nova prática tendente a admitir acordos em forma simplificada, que foram cristalizados, sobretudo, na prática norte-americana. A tendência no sentido de minimizar a competência legislativa pode ser verificada em função da aceleração exponencial da conclusão de acordos executivos. O objetivo do presente artigo é, portanto, analisar o surgimento e a evolução dos acordos em forma simplificada para, em seguida, avaliar o emprego de tais acordos no Brasil, país que seguiu a prática constitucional moderna no sentido de admitir a conclusão de acordos sem intervenção obrigatória do poder legislativo. Tal prática, apesar dos inúmeros debates que se instalaram na matéria, afigura-se crescente e constitui, atualmente, o principal meio de sujeição internacional dos Estados.

  7. Federações de repositórios: conceitos, políticas, características e tendências

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    Milton Shintaku

    Full Text Available O surgimento das federações de repositórios, há mais de dez anos, tem apoiado a disseminação da literatura científica em acesso aberto. Entretanto, há pouca informação acadêmica sobre essas ferramentas. Nesse sentido, o presente estudo tem por objetivo apresentar informações sobre as federações, de forma a contribuir com esse tema, que ainda pouco explorado. Um estudo qualitativo, utilizando técnicas de pesquisa documental, para a verificação dos conceitos, políticas, características e tendências das federações disponíveis na internet. Os resultados revelaram consenso em vários aspectos, com um cenários colaborativo e pouco estudado, embora seja de interesse acadêmico, em que as federações fomentam a criação de repositórios. Com isso, o estudo contribui com informações sobre as federações, apresentando um tema atual.

  8. Desarrollo de un método analítico para la determinación de selenio en huevos fortificados de gallinas (Isa Brown) por espectroscopia de absorción atómica con generación de hidruros

    OpenAIRE

    Gutiérrez Peña, Luís Vicente; Carrero, Pablo E; Delgado C, Yelitza J; Picón, David; Paz, Luis A; Vielma, José R; Quintero, Arlenis Y; Gutiérrez, Ever O; Gutiérrez, Iserslis A

    2014-01-01

    El huevo es una fuente proteica de uso masivo, en consideración a su bajo costo, es consumido con mayor frecuencia por toda la población. Por esta razón, es de gran interés introducir al mercado un tipo de huevo "saludable", que disminuya los riesgos ligados a enfermedades cardiovasculares y que actúe como antioxidante. Por ello, se evaluó la incorporación del Selenio Orgánico (Sel-Plex®, Alltech Inc) en el programa de alimentación de gallinas ponedoras comerciales raza isa brown con el objet...

  9. Afecção do tendão supra-espinal e afastamento laboral Supraspinatus tendon affection and sick leave

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    Josiane Schadeck de Almeida

    2008-04-01

    Full Text Available As afecções do manguito rotador, dentre elas as relacionadas ao tendão supra-espinal, são problemas comuns na população, sobretudo devido à sobrecarga ocupacional, o que leva a altos índices de afastamento do trabalho. Buscou-se, então, comparar a necessidade de afastamento de trabalho entre os diferentes estados da afecção do tendão supra-espinal e entre cinco diferentes grupos profissionais, tendo a participação de pacientes que apresentavam diagnóstico da afecção. Os indivíduos foram agrupados quanto ao estado da doença (tendinite, ruptura parcial, ruptura total e quanto aos aspectos biomecânicos da ocupação (ramo de serviços, construção civil, trabalhadores domésticos, lavradores e seguranças. Teste qui-quadrado de Pearson, análise de dependência e teste exato para uma proporção foram realizados. Os resultados apontaram que 62 (55% estavam afastados da atividade laboral e que os grupos com maior número de afastados foram o do ramo de serviços (38,71% e lavradores (22,58%, segundo Pearson. A maior freqüência de casos de afastamento foi registrada no estágio de tendinite (pRotator cuff disease, among others damage of the supraspinatus tendon mainly caused by work overload, is a common problem in the population resulting in a high incidence of sick leaves. In the present survey we sought to compare the need for sick leaves in relation to different stages of supraspinatus tendon affection and in relation to five different groups of workers. Our study counted with the participation of patients who were diagnosed with this condition. The individuals were grouped according to stages of the disease (tendonitis, partial rupture, total rupture and according to the biomechanical aspects of their occupation (general services, civil construction, domestic workers, farm workers and security guard services. Statistical analysis was performed using Pearson's chi-square test, dependence analysis and exact test. Results

  10. Suicide time trends in Brazil from 1980 to 2005 Tendência temporal do suicídio no Brasil no período 1980-2005

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    Fabíola Stolf Brzozowski

    2010-07-01

    Full Text Available The aim of this study was to describe suicide time trends in Brazil from 1980 to 2005. The data were obtained from the National Mortality Information System and the Brazilian Institute of Geography and Statistics (IBGE. Suicides rates were calculated for the entire period for the country as a whole and the 26 States and Federal District. Annual increases or decreases in mortality rates were also estimated using Prais-Winsten generalized linear regression. The mean suicide rate was 4.12 per 100,000 inhabitants (6.45/100,000 in men and 1.80/100,000 in women. The study showed an increasing suicide trend in men (+1.41% per year, 95%CI: 1.00;1.23 and a decreasing trend in women (-0.53% per year, 95%CI: -0.04;-1.02. Suicide rates increased with age. In general, for all age groups and for both genders, the highest rates were in São Paulo and in the States of the South and Central-West regions.O objetivo deste estudo foi descrever a tendência temporal das taxas de mortalidade por suicídio no Brasil, no período de 1980 a 2005. Os dados foram obtidos junto ao Sistema de Informações sobre Mortalidade e ao Instituto Brasileiro de Geografia e Estatística. Foram calculadas as taxas médias de suicídio para todo o período, para cada estado, Distrito Federal e para o país como um todo, segundo sexo e faixas etárias. Também foram calculadas as variações médias anuais do suicídio pela regressão linear generalizada de Prais-Winsten. Foi observada, no período, taxa média de suicídio de 4,12 por 100 mil habitantes, variando de 6,45 por 100 mil habitantes entre homens a 1,80 por 100 mil habitantes entre mulheres, com tendência de ascensão entre os homens (+1,41% ao ano, IC95%: 1,00;1,23 e de declínio entre as mulheres (-0,53%, IC95%: -0,04;-1,02. O suicídio aumentou com o avanço da idade em ambos os sexos. De uma maneira geral, para todas as faixas etárias e para ambos os sexos, as maiores taxas foram encontradas em São Paulo e nos estados

  11. Partos cesáreos no Piauí: tendência e fatores associados no período 2000-2011

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    Alberto Madeiro

    Full Text Available Resumo OBJETIVO: analisar a tendência da proporção de partos cesáreos e fatores associados no Piauí, Brasil, de 2000 a 2011. MÉTODOS: estudo de série temporal e transversal, com dados dos partos hospitalares de primíparas registrados no Sistema de Informações sobre Nascidos Vivos (Sinasc. RESULTADOS: a proporção de partos cesáreos aumentou de 34,4% em 2000 para 52,1% em 2011 (variação percentual anual +4,4; IC95% 3,6;5,1; mulheres brancas (RP=1,72; IC95% 1,63;1,86, com 40 anos ou mais de idade (RP=2,17; IC95% 2,09;2,28, com 12 anos ou mais de estudo (RP=1,86; IC95% 1,77;1,96, que realizaram sete ou mais consultas de pré-natal (RP=2,08; IC95% 1,97;2,18, residentes em municípios com mais de 300 mil habitantes (RP=1,68; IC95% 1,62;1,80 e com índice de desenvolvimento humano mais elevado (RP=1,61; IC95% 1,51;1,73 mostraram maiores proporções de partos cesáreos. CONCLUSÃO: a ocorrência de partos cesáreos foi elevada e mais frequente em mulheres de baixo risco obstétrico.

  12. Parâmetros e tendência genética da produção de leite de cabra no Brasil

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    Gonçalves Heraldo Cesar

    2002-01-01

    Full Text Available A caprinocultura leiteira no Brasil, apesar de ser uma atividade rural consolidada há algumas décadas, tem se mostrado totalmente dependente de outros países no que se refere ao melhoramento genético. A maioria dos plantéis existentes atualmente tem como base animais importados, e a renovação do material genético é feita por meio da importação de sêmen. Inexistem informações sobre o valor genético dos animais e sua evolução no decorrer dos anos. No presente trabalho, foram estimadas a herdabilidade e a repetibilidade da produção de leite utilizando o REML. Os valores obtidos foram 0,21557 e 0,21564, respectivamente. Para a predição do valor gênico dos animais, foi usado o procedimento BLUP com modelo animal. A mudança na tendência genética anual estimada por um modelo quadrático foi -0,8109 kg/ano², indicando desaceleração no ganho genético. A correlação de Pearson entre os valores gênicos dos bodes estimados com base na média da capacidade provável de produção das filhas obtida pelo método de mínimos quadrados com as estimadas pelas equações do modelo misto foi de 0,5751. A correlação de SPEARMAN entre as classificações dos bodes obtidos pelos dois métodos foi de 0,5813.

  13. Reconstrucción artroscópica del ligamento cruzado anteriorcon injerto autólogo del tendón patelar

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    Roberto Joaquín Del Gordo D´Amato

    2014-06-01

    Full Text Available ResumenSe presenta un estudio descriptivo de corte transversal, en el cual treinta y seis pacientes fueron intervenidos quirúrgicamente para reconstrucción artroscópica de ligamento cruzado anterior con auto injerto de tendón patelar en el periodo comprendido de enero del 2004 y enero del 2006. De los treinta y seis pacientes que hicieron parte del presente estudio, en 25 pacientes se practicó la fijación con tornillos de interferencia femoral y tibial, y en los 11 restantes en el componente femoral clavijas reabsorvibles y en el componente tibial tornillo de interferencia. Las variables consideradas fueron rango de movilidad, reintegro a la vida deportiva, presencia de lesiones asociadas, complicaciones y nivel de satisfacción. En todos los pacientes fue aplicada la escala de Lisholm. Los resultados obtenidos se expresan en términos de relación porcentual y son comparables con los reportados en otros estudios. (Duazary 2008; 82-89AbstractWe are present a descriptive transversal study with 36 patients, who were operative treatment with arthroscopic reconstruction of anterior cruciate ligament with patellar-ligament graft, between January 2004 – January 2006.Of 36 patients included in this studied were operated 25 patients with interference screw fixation in femoral and tibial, in order to, 11 patients were treated with absorbable femoral pins and interference screw in tibia. The variables considerated were morbidity, sport practice again, associated lesions, complications and satisfaction level. In all patients the Lisholm scale was aplicated. The results were expressed in porcental relation and were similarly with other studies.Key Words: Stability; Cruciate Anterior Ligament; Reconstruction; Autogenous patellar-ligament graft.

  14. Tendências dos índices de precipitação no estado do Ceará Trends of precipitation indices in Ceará state

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    Carlos Antonio Costa dos Santos

    2009-03-01

    Full Text Available O principal objetivo deste trabalho é prover novas informações sobre as tendências na precipitação total e eventos extremos de precipitação sobre o Estado do Ceará, fazendo uma análise de diferentes índices de detecção de mudanças climáticas, baseados em dados de precipitação pluvial diária. Utilizaram-se dados de precipitação de 18 postos, no período de 1935 a 2006, representando todas as microrregiões do Estado; o software utilizado no processamento e controle de qualidade dos dados foi o RClimdex 1.9.0. Com base nos resultados encontrados, observou-se que ocorreram mudanças locais na precipitação, assim como um visível aumento nas condições de umidade sobre o Ceará.The principal objective of this work is to provide new information on the trends in the total precipitation and extreme events of precipitation in the State of Ceará, making an analysis of different indices of detection of climatic changes, based on data of daily precipitation. Precipitation data of 18 stations were used, in the period from 1935 to 2006, representing all the microregions of the State; the software used in the processing and quality control of the data was RClimdex 1.9.0. The results show local changes in the precipitation and a visible increase in the humidity conditions in Ceará.

  15. Global Derivatives Market

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    Stankovska Aleksandra

    2017-06-01

    Full Text Available Globalization of financial markets led to the enormous growth of volume and diversification of financial transactions. Financial derivatives were the basic elements of this growth. Derivatives play a useful and important role in hedging and risk management, but they also pose several dangers to the stability of financial markets and thereby the overall economy. Derivatives are used to hedge and speculate the risk associated with commerce and finance.

  16. Engineering Faculty Indicate High Levels of Awareness and Use of the Library but Tend to Consult Google and Google Scholar First for Research Resources

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    Elaine Sullo

    2016-09-01

    Full Text Available A Review of: Zhang, L. (2015. Use of library services by engineering faculty at Mississippi State University, a large land grant institution. Science & Technology Libraries, 34(3, 272-286. http://dx.doi.org/10.1080/0194262X.2015.1090941 Objective – To investigate the engineering faculty’s information-seeking behaviour, experiences, awareness, and use of the university library. Design – Web-based survey questionnaire. Setting – The main campus of a state university in the United States of America. Subjects – 119 faculty members within 8 engineering departments. Methods – An email invitation to participate in a 16-item electronic survey questionnaire, with questions related to library use, was sent in the spring of 2015 to 119 engineering faculty members. Faculty were given 24 days to complete the survey, and a reminder email was sent 10 days after the original survey invitation. Main Results – Thirty-eight faculty members responded to the survey, representing a response rate of 32%. Overall, faculty had a high level of use and awareness of both online and physical library resources and services, although their awareness of certain scholarly communication services, such as data archiving and copyright advisory, was significantly lower. Faculty tend to turn to Google and Google Scholar when searching for information rather than turning to library databases. Faculty do not use social media to keep up with library news and updates. The library website, as well as liaison librarians, were cited as the primary sources for this type of information. Conclusions – The researcher concludes that librarians need to do a better job of marketing library resources, such as discipline-specific databases, as well as other library search tools. Because faculty use web search engines as a significant source of information, the author proposes further research on this behaviour, and suggests more action to educate faculty on different search tools

  17. Tendência da mortalidade por suicídio na população brasileira e idosa, 1980-2006

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    Maria Cecília de Souza Minayo

    2012-04-01

    Full Text Available OBJETIVO: Descrever a mortalidade por suicídio no Brasil, com destaque para a população idosa. MÉTODOS: Análise temporal e estudo de tendência por regressão polinomial de suicídios na população acima de dez anos no Brasil e no Estado do Rio de Janeiro de 1980 a 2006. Os dados foram extraídos do Sistema de Informações sobre Mortalidade e as taxas, calculadas segundo sexo e faixa etária, considerando-se a população residente fornecida pelo Datasus por 100 mil habitantes. Para os anos de 1980 a 1995, utilizou-se a nona revisão da Classificação Internacional de Doenças e Problemas Relacionados à Saúde, e para 1996 a 2006, a décima revisão. RESULTADOS: Crescimento significativo foi observado nas taxas de suicídio na população brasileira e no Rio de Janeiro (5,7 e 3,1 para cada 100 mil habitantes, respectivamente em 2006. Esse incremento ocorreu pelo aumento dos suicídios na população masculina em todas as idades. A curva crescente aconteceu principalmente entre homens maiores de 60 anos. O incremento não foi estatisticamente significativo entre homens e houve decréscimo entre mulheres no Rio de Janeiro. Os principais meios de suicídio utilizados pelos homens foram enforcamento, sufocação, estrangulamento e armas de fogo. Para as mulheres, o enforcamento também ocupou a primeira posição, seguido pela ingestão de substâncias, atiramento ao fogo e precipitação de altura. A elevada taxa de indefinição dos meios ressaltou problemas na qualidade dos dados. CONCLUSÕES: Suicídios são eventos significantes na população masculina, sobretudo entre homens idosos, ao longo do tempo. No Rio de Janeiro, as taxas entre homens idosos também são maiores, mas não estatisticamente significantes. Segundo a Organização Mundial da Saúde e o Ministério da Saúde, o suicídio é passível de prevenção e existem cuidados preconizados para cada grupo etário.

  18. Tendências temporais de atividade física no Brasil (2006-2009 Time trends of physical activity in Brazil (2006-2009

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    Pedro C Hallal

    2011-09-01

    Full Text Available OBJETIVO: Analisar as tendências temporais de atividade física (AF nas capitais brasileiras entre 2006 e 2009. MÉTODOS: A análise apresentada neste artigo é baseada nos dados do VIGITEL, totalizando uma amostra anual aproximada de 54.000 indivíduos. Foram analisados indicadores de AF no tempo livre, trabalho, em casa e no deslocamento, além do tempo assistindo à televisão e de inatividade considerando todos os domínios de AF. A variação dos indicadores no período foi aferida por meio de modelos de regressão de Poisson, tendo como variável explanatória o ano do inquérito. Foi considerada significativa a evolução correspondente a um coeficiente de regressão diferente de zero (pOBJECTIVE: To examine time trends in physical activity (PA in Brazilian state capitals from 2006 to 2009. METHODS: This analysis is based on data from the Telephone-based Surveillance of Risk and Protective Factors for Chronic Diseases (VIGITEL accounting for an annual sample of approximately 54,000 individuals. PA indicators were analyzed in free time (leisure, work, home and transportation, time spent in front of the television and inactivity considering all PA domains. Poisson regression models were used to measure the variation of indicators over time. We considered the changes corresponding to a regression coefficient different from zero as being statistically significant (p<0.05. RESULTS: The percentage of active commuters increased from 11.7 to 14.4% (p<0.001 whereas the proportion of physically inactive individuals in the four domains decreased from 11.7 to 8.7% (p<0.001. There were no significant changes in the other indicators. Women were less active than men in all indicators, except for household chores. However, in this indicator the percentage of active women decreased from 71.4 to 67.1% (p<0.001. Between 2006 and 2009, PA levels in the Brazilian population were stable during free time and household chores, but increased in transportation

  19. A transição nutricional no Brasil: tendências regionais e temporais Nutritional transition in Brazil: geographic and temporal trends

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    Malaquias Batista Filho

    2003-01-01

    Full Text Available Tendo como principal fonte de informações três estudos transversais realizados nas décadas de 70, 80 e 90, faz-se uma análise da transição nutricional do Brasil, referenciada no rápido declínio da prevalência de desnutrição em crianças e elevação, num ritmo mais acelerado, da prevalência de sobrepeso/obesidade em adultos. A correção dos déficits de estatura foi de 72% em crianças urbanas e de 54,4% no meio rural, enquanto a ocorrência de obesidade duplicou ou triplicou em homens e mulheres adultos nos extremos da série temporal analisada. Com exceção do Nordeste rural, a prevalência de desnutrição em mulheres adultas declinou para taxas aceitáveis (em torno de 5% a partir de 1989. Inversamente, as anemias continuam com prevalências elevadas e indicações de tendências epidêmicas. Descreve-se a evolução do estado nutricional da população brasileira segundo macrorregiões e distribuição social, analisando-se os prováveis fatores das mudanças ocorridas.Based on three cross-sectional studies conducted in the 1970s, 80s, and 90s, an analysis of the nutritional transition in Brazil was performed. This analysis found a rapid decrease in the prevalence of childhood malnutrition and an even more rapid increase in adult overweight/obesity. Correction of the height deficit was 72% in urban children and 54.4% in rural children. Obesity rates doubled or tripled in adult men and women at the extremes of the time series analyzed. Excluding the rural Northeast, malnutrition prevalence in adult women dropped to acceptable rates (about 5% starting in 1989. Inversely, anemia continued to display a high prevalence, and there is indication of an epidemic trend. The evolution of nutritional status in the Brazilian population according to macro-regions and social distribution is reported. The likely factors for the observed changes are analyzed.

  20. Classificação e tendências climáticas em Lavras, MG Climatic classification and tendencies in Lavras region, MG

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    Antonio Augusto Aguilar Dantas

    2007-12-01

    Full Text Available Objetivou-se com este trabalho avaliar a tendência de dados climáticos nos últimos 14 anos, na região de Lavras, MG, comparando-os com aqueles da série histórica do período de 1961 a 1990. Foi utilizado o método do balanço hídrico de Thornthwaite & Mather (1955para os dados do período de 1961-1990 e para os dados recentemente observados de 1991-2004. O método do balanço hídrico de Thornthwaite considera a evapotranspiração potencial, a precipitação pluvial, o armazenamento de água no solo e seu subsequente uso. Este método também apresenta os períodos de excesso e deficiência hídrica, então utilizados no método de classificação climática de Thornthwaite para determinar os índices de umidade e de aridez. Os índices resultaram na fórmula climática de Thornthwaite que nesta comparação, mudou de B3 r B'3 a' para B2 r B'3 a' no período mais recente. A classificação climática de Köppen, também utilizada neste trabalho não apresentou diferenças para ambos os períodos, permanecendo Cwa.The purpose of this study was to evaluate the climatic data tendency in the last 14 years of monthly rainfall and temperatures in Lavras region, MG state , compared to those of the historical series of 1961-1990 period. The Thornthwaite's water balance method was employed for the climatological data of 1961-1990 and for the last observed data of 1991-2004. The Thornthwaite's & Mather´s water balance method considers the potential evapotranspiration, the rainfall, the storage of water in the ground and its subsequent use. This method also shows hidric excess and deficiency periods, then used on the Thornthwaite's climatic classification method to determine the moisture and aridity index of the climate. The index resulted on the Thornthwaite's climatic formula wich changed from B3 r B'3 a' to B2 r B'3 a' in the most recent reiod. The Köppen climatic classification method, also employed in this work, showed no changes, remaining

  1. Luxação acromioclavicular: tratamento e reabilitação. Perspectivas e tendências atuais do ortopedista brasileiro

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    Gustavo Gonçalves Arliani

    2015-10-01

    Full Text Available Resumo Objetivo: Avaliar as condutas e os procedimentos feitos pelos cirurgiões ortopédicos do Brasil no tratamento e na reabilitação das luxacões acromioclaviculares do ombro. Métodos: Foi aplicado um questionário de oito questões fechadas que abordavam tópicos relacionados ao tratamento e à reabilitação das luxacões acromioclaviculares aos cirurgiões ortopédicos brasileiros nos três dias do 45° Congresso Brasileiro de Ortopedia e Traumato logia de 2013. ResuItados: Preencheram completamente o questionário e fizeram parte da amostra ana lisada 122 cirurgiões. A maior parte era proveniente da Região Sudeste. Na amostra, 67% dos participantes optariam pelo tratamento cirúrgico em pacientes com luxação acro mioclavicular grau 3. Em relacão à técnica preferida para tratamento cirúrgico das luxacões acromioclaviculares agudas, a maioria dos cirurgiões usa amarrilho subcoracoide com fixacão acromioclavicular e transferência do ligamento coracoacromial (25,4%. Quando perguntados sobre complicates encontradas após a cirurgia, 43,4% e 32,8% dos partici pantes, respectivamente, responderam que deformidade residual na articulação operada e dor foram as complicates mais vistas no período pós-operatório. Conclusoes: Apesar de não haver consenso no tratamento e na reabilitação das luxacões acro mioclaviculares, há evolucão em alguns tópicos analisados no questionário aplicado para os ortopedistas nacionais. No entanto, mais estudos prospectivos controlados são necessários para avaliar o benefício clínico e científico dessas tendências.

  2. Inquérito Brasileiro de Diálise Crônica 2013 - Análise das tendências entre 2011 e 2013

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    Ricardo Cintra Sesso

    2014-12-01

    Full Text Available Introdução: Dados nacionais sobre diálise crônica têm tido impacto no planejamento do tratamento. Objetivo: Apresentar dados do inquérito da Sociedade Brasileira de Nefrologia sobre os pacientes com doença renal crônica em tratamento dialítico em julho de 2013 e comparar com dados de 2011- 12. Métodos: Levantamento de dados de unidades de diálise do país. A coleta de dados foi feita utilizando questionário preenchido on-line pelas unidades de diálise. Resultados: Trezentos e trinta e quatro (51% unidades responderam ao inquérito. Em julho de 2013, o número total estimado de pacientes em diálise foi de 100.397. As estimativas nacionais das taxas de prevalência e de incidência de tratamento dialítico foram de 499 (variação: 284 na região Norte e 622 na Sul e 170 pacientes por milhão da população, respectivamente. O número estimado de pacientes que iniciaram tratamento em 2013 foi 34.161. A taxa anual de mortalidade bruta foi de 17,9%. Dos pacientes prevalentes, 31,4% tinham idade ≥ 65 anos, 90,8% estavam em hemodiálise e 9,2% em diálise peritoneal, 31.351 (31,2% estavam em fila de espera para transplante, 30% tinham diabetes, 17% tinham PTH > 600 pg/ml e 23% hemoglobina < 10 g/dl. Cateter venoso era usado como acesso em 15,4% dos pacientes em hemodiálise. Conclusão: O número absoluto de pacientes em diálise tem aumentado 3% ao ano nos últimos 3 anos. As taxas de prevalência e incidência de pacientes em diálise ficaram estáveis, e a taxa de mortalidade tendeu a diminuir em relação a 2012. Houve tendência a melhor controle da anemia e dos níveis de PTH.

  3. Tendencias internacionales del cuidado de Enfermería Tendências internacionais do cuidado de enfermagem International trends in nursing care

    Directory of Open Access Journals (Sweden)

    Ángela María Salazar Maya

    2011-07-01

    Full Text Available Se presentan las tendencias internacionales del cuidado de enfermería, que están cambiando a un ritmo inesperado a nivel internacional. El envejecimiento, las consecuencias de la urbanización y globalización aceleran la propagación de las enfermedades transmisibles a nivel mundial e incrementan la carga de trastornos crónicos y degenerativos. Los contextos de los sistemas de salud, cada vez más complejos, se preocupan por el incremento del gasto sanitario, la disparidad en la atención y la hospitalización de corta estancia. El usuario de los sistemas de salud, a futuro, será predominantemente mayor de 65 años con diagnósticos multisistémicos y crónicos; más informado sobre la salud, la enfermedad y los sistemas de calificación de proveedores de servicios de salud. La enfermería, eje del equipo de salud, se caracterizará por la escasez de profesionales en un contexto altamente tecnológico, en el que el cuidado se sustentará en la relación interpersonal e indagación científica multiparadigmática con una franca tendencia a los cuidados estandarizados. Como disciplina, la Enfermería, seguirá fortalecimiento su cuerpo de conocimientos. La autonomía de la enfermería será de gran trascendencia, desarrollando responsabilidades propias y asegurando la gestión de cuidados.Se apresentam as tendências internacionais do cuidado de enfermagem, que estão mudando a um ritmo inesperado a nível internacional. O envelhecimento, as conseqüências da urbanização e globalização aceleram a propagação das doenças transmissíveis a nível mundial e incrementam o ônus de transtornos crônicos e degenerativos. Os contextos dos sistemas de saúde, cada vez mais complexos, preocupam-se pelo incremento do gasto sanitário, a disparidade no atendimento e a hospitalização de curta estadia. O usuário dos sistemas de saúde, a futuro, será predominantemente maior de 65 anos com diagnósticos multi-sistémicos e crônicos; mais

  4. Risk and Derivative Price

    OpenAIRE

    Yusuke Osaki

    2007-01-01

    We consider an asset market traded three types of assets: the risk–free asset, the market portfolio and derivatives written on the market portfolio return. We determine a sufficient condition to guarantee that noise risk monotonically changes their derivatives. The condition is that Arrow–Pratt absolute risk aversion is decreasing and convex.

  5. Financial Derivatives in China

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Francis Repka sees bright prospects for the future development of the financial derivatives market in China. Repka,Vice President of the Asian Bond Finance Department of Societe Generale, says the situation in France just after the birth of derivatives was very similar to the situation in China today.

  6. Vitamin D derivatives

    International Nuclear Information System (INIS)

    Deluca, H.F.; Schnoes, H.K.; Napoli, J.L.; Fivizzani, M.A.

    1982-01-01

    The chemical preparation of 26,27-isotopically labelled vitamin D 3 derivatives of high specific activity is described. These labelled vitamin D derivatives are useful in the determination of vitamin D metabolite levels in the blood and tissues of man and animals. (U.K.)

  7. Taxation of Derivatives

    DEFF Research Database (Denmark)

    Dyppel, Katja Joo

    2013-01-01

    The main objective for this thesis is to analyse and systematise the Danish legislation on taxation of derivatives. According to financial terminology, a derivative is a financial instrument. Its value is derived from changes in the value of one or more underlying assets.The most common derivatives...... in the Danish tax legislation. However, contracts known as forwards (terminskontrakter) and options (aftaler om køberetter og salgsretter) are generally included in the term financials contracts covered by the Danish Act on Taxation of Gains and Losses on Claims and Debt. The main part of the analysis deals...... with the scope of sections 29-33 of the Danish Act on Taxation of Gains and Losses on Claims and Debt and the tax consequences for the covered financial contracts. In the analysis of taxation of derivatives, the fundamental issues of qualification and tax treatment of the instruments are dealt with....

  8. Autotransplante de cordas tendíneas: nova técnica para o tratamento cirúrgico da insuficiência mitral por rotura de cordas tendíneas da cúspide anterior Allotransplantation of chordae tendineae: new technique for the surgical approach of mitral insufficiency

    Directory of Open Access Journals (Sweden)

    Francisco Gregori Jr

    1992-12-01

    Full Text Available Uma das causas mais freqüentes de prolapso valvar mitral, com conseqüente regurgitação, é a rotura de cordas tendíneas. Várias técnicas têm sido empregadas em tal situação. Entretanto, a substituição valvar mitral tem sido o procedimento mais utilizado. E apresentada uma nova técnica cirúrgica empregada em 4 pacientes com insuficiência valvar mitral severa devido a rotura de cordas tendíneas da cúspide anterior da valva mitral. Um autotransplante de cordas da valva tricúspide para a valva mitral é realizado. Em 2 casos, um retalho é retirado da cúspide anterior da valva tricúspide com cordas tendíneas e parte do músculo papilar correspondente. Nos outros 2 casos a cúspide posterior da valva tricúspide foi retirada, inteiramente, com cordas e músculo papilar. Na primeira variante técnica, a cúspide anterior da valva tricúspide foi reparada e, na segunda, através, da plicatura do anel, a valva tricúspide foi transformada em bicúspide. A peça retirada é transplantada para a valva mitral, sendo suturada a cúspide doadora com a cúspide anterior da valva mitral e o músculo papilar doador com o topo do músculo papilar posterior da valva mitral em 3 casos e com o músculo papilar anterior e 1 caso. Os 4 pacientes foram reestudados clínica e laboratorialmente aos 15, 11, 2 e 1 mês de pós-operatório, respectivamente, com execelente evolução. Apesar da limitada experiência, acreditamos ser esta nova técnica uma boa alternativa para o tratamento cirúrgico da insuficiência mitral por rotura de cordas tendíneas da cúspide anterior.One of the most frequent causes of mitral valve prolapse is rupture of the chordae tendineae. Several techniques have been used to correct severe mitral regurgitation. However, mitral valve replacement is the principal surgical approach to it. We describe a technique used in four patients with marked mitral regurgitation due to ruptured chordae tendineae of the anterior leaflet. We

  9. Tendències investigadores de la ciència de la informació i la biblioteconomia a Iberoamèrica i al Carib

    Directory of Open Access Journals (Sweden)

    Menéndez Echavarría, Alfredo Luis

    2015-12-01

    Full Text Available Objectiu: aquest article presenta categories que mostren tendències investigadores de la ciència de la informació i la biblioteconomia en l'entorn d'Iberoamèrica i el Carib. Les categories han estat producte d'una recerca l'objectiu de la qual es relaciona amb l'anàlisi d'aquests aspectes predictius i prospectius de la disciplina, així com la configuració de l'horitzó d'aquest camp des d'una perspectiva científica. -- Metodologia: l'enfocament que assumeix el projecte és de caràcter mixt, ja que integra l'anàlisi quantitativa i qualitativa, tenint en compte que s'utilitzen tècniques bibliomètriques, i procediments que integren l'ús de variables de mesura i obtenció d'indicadors de producció científica. De la mateixa manera, s'examinen i descriuen els articles seleccionats respecte del seu contingut teoricoepistemològic, recuperats del Web of Science, informació d'Iberoamèrica i del Carib, entre els anys 2009 i 2013, corresponents als títols de revistes que integren la categoria temàticaObjetivo: este artículo presenta categorías que evidencian tendencias investigativas de la ciencia de la información y la bibliotecología en el entorno de Iberoamérica y el Caribe. Estas han sido producto de una investigación cuyo objetivo se relaciona con el análisis de estos aspectos predictivos y prospectivos de la disciplina, así como la configuración del horizonte de este campo desde una perspectiva científica. -- Metodología: el enfoque que asume el proyecto es de carácter mixto, pues integra el análisis cuantitativo y cualitativo, teniendo en cuenta que se utilizan técnicas bibliométricas, y procedimientos que integran el uso de variables de medición y obtención de indicadores de producción científica. De igual modo se examinan y describen los artículos seleccionados respecto de su contenido teórico-epistemológico, recuperados de la Web of Science, información de Iberoamérica y el Caribe, entre los años 2009 y

  10. Tendência secular da doença diarréica na infância na cidade de São Paulo (1984-1996

    Directory of Open Access Journals (Sweden)

    Benicio Maria Helena D'Aquino

    2000-01-01

    Full Text Available OBJETIVO: Estimar a prevalência e a distribuição social da doença diarréica na infância, estabelecer a tendência secular dessa enfermidade e analisar sua determinação, através dos dados coletados por dois inquéritos domiciliares realizados na cidade de São Paulo, SP, em 1984/85 e 1995/96. MÉTODOS: Os inquéritos estudaram amostras probabilísticas da população residente na cidade com idades entre zero e 59 meses (1.016 em 1984/85 e 1.280 em 1995/96. Nos dois inquéritos foram estimadas a prevalência instantânea da diarréia (proporção de crianças com três ou mais evacuações líquidas no dia da entrevista domiciliar e a incidência anual de internações hospitalares pela doença. Esses dois indicadores foram calculados a partir de entrevistas domiciliares feitas por médicos pediatras e respondidas pelas mães das crianças. Nos dois inquéritos, as entrevistas foram distribuídas ao longo de um período de cerca de 12 meses, de modo a garantir uma varredura uniforme das várias áreas da cidade ao longo das quatro estações do ano. O estudo da distribuição social da doença diarréica levou em conta tercis da renda familiar per capita em cada um dos inquéritos. A estratégia analítica para estudar os determinantes da evolução da prevalência da doença na população empregou modelos hierárquicos de causalidade, análises multivariadas de regressão e procedimentos análogos aos utilizados para calcular riscos atribuíveis populacionais. RESULTADOS/CONCLUSÕES: Houve entre os inquéritos reduções expressivas na prevalência instantânea da diarréia (de 1,70% para 0,90% e na incidência anual de hospitalizações pela doença (de 2,21 para 0,79 internações por 100 crianças-ano. O declínio desses indicadores foi mais intenso no terço mais pobre da população, o que contribuiu para reduzir a desigualdade social quanto à ocorrência da doença. Melhorias no poder aquisitivo das famílias e na cobertura da

  11. Tendências da produção científica em odontologia no Brasil Scientific output trends in oral health in Brazil

    Directory of Open Access Journals (Sweden)

    Aldo Angelim Dias

    2008-07-01

    Full Text Available OBJETIVO: Descrever a tendência da produção científica odontológica no Brasil, destacando-se a área de saúde bucal coletiva, nos primeiros anos do século XXI. MÉTODOS: Os resumos de trabalhos apresentados nas reuniões da Sociedade Brasileira de Pesquisa Odontológica (SBPqO de 2001 a 2006 foram avaliados em termos do seu desenho metodológico (estudo agregado ou individuado; estudo observacional ou de intervenção; estudo transversal ou longitudinal, natureza geral (revisões bibliográficas, estudos com seres humanos ou pesquisas laboratoriais e enquadramento em uma das 19 especialidades reconhecidas pelo Conselho Federal de Odontologia (CFO. Dos 10 406 trabalhos apresentados nesse período, foram lidos 5 203 (50,0% do total. RESULTADOS: Quanto ao desenho metodológico, 87,5% dos resumos eram do tipo operativo individuado e 12,5% do tipo agregado. Na classificação da natureza geral da pesquisa, 41,7% dos resumos tratavam de estudos com seres humanos. Os resumos restantes (58,3% tratavam de pesquisas laboratoriais in vitro (31,1%, pesquisas laboratoriais in vivo (23,6% e revisões bibliográficas (3,6%. Com relação às áreas de conhecimento do CFO, apenas cinco atingiram percentuais de ocorrência superiores a 10,0%: dentística, periodontia, endodontia, odontopediatria e saúde coletiva. CONCLUSÕES: A produção científica odontológica brasileira no período de 2001 a 2006 foi equilibrada, com crescente interesse na área de saúde bucal coletiva.OBJECTIVE: To describe dental research trends in Brazil (especially population-based oral health in the early Twenty-first Century. METHODS: The abstracts of studies presented at meetings of the Brazilian Society for Dental Medicine Research (Sociedade Brasileira de Pesquisa Odontológica from 2001-2006 were assessed in terms of methodological design (aggregate or population-based and individual-based studies, observational and intervention studies, cross-sectional and longitudinal

  12. Precipitation measurement and derivation of precipitation inclination in a windy mountainous area in northern Costa Rica. Scientific Briefing.

    NARCIS (Netherlands)

    Frumau, K.F.A.; Bruijnzeel, L.A.; Tobón, C.

    2011-01-01

    Over small-scale topography in windy areas, precipitation tends to be redistributed by wind through the modification of precipitation inclination. The latter is often derived from wind speed and conventional rain gauge records by application of relations-derived mainly for convective rainfall

  13. Ecdysteroids Sensitize MDR and Non-MDR Cancer Cell Lines to Doxorubicin, Paclitaxel, and Vincristine but Tend to Protect Them from Cisplatin

    Directory of Open Access Journals (Sweden)

    Ana Martins

    2015-01-01

    Full Text Available Ecdysteroids, analogs of the insect molting hormone, are known for their various mild, nonhormonal bioactivities in mammals. Previously, we reported that less-polar ecdysteroids can modulate the doxorubicin resistance of a multidrug resistant (MDR mouse lymphoma cell line expressing the human ABCB1 transporter. Here, we describe the ability of 20-hydroxyecdysone (1 and its mono- (2 and diacetonide (3 derivatives to sensitize various MDR and non-MDR cancer cell lines towards doxorubicin, paclitaxel, vincristine, or cisplatin. Drug IC50 values with or without ecdysteroid were determined by MTT assay. Compound 3 significantly sensitized all cell lines to each chemotherapeutic except for cisplatin, whose activity was decreased. In order to overcome solubility and stability issues for the future in vivo administration of compound 3, liposomal formulations were developed. By means of their combination index values obtained via checkerboard microplate method, a formulation showed superior activity to that of compound 3 alone. Because ecdysteroids act also on non-ABCB1 expressing (sensitive cell lines, our results demonstrate that they do not or not exclusively exert their adjuvant anticancer activity as ABCB1 inhibitors, but other mechanisms must be involved, and they opened the way towards their in vivo bioactivity testing against various cancer xenografts.

  14. Superstability of Generalized Derivations

    Directory of Open Access Journals (Sweden)

    Ansari-Piri Esmaeil

    2010-01-01

    Full Text Available We investigate the superstability of the functional equation , where and are the mappings on Banach algebra . We have also proved the superstability of generalized derivations associated to the linear functional equation , where .

  15. Amphetamine derivative related deaths.

    Science.gov (United States)

    Lora-Tamayo, C; Tena, T; Rodríguez, A

    1997-02-28

    Amphetamine its methylendioxy (methylendioxyamphetamine methylenedioxymethylamphetamine, methylenedioxyethylamphetamine) and methoxy derivatives (p-methoxyamphetamine and p-methoxymethylamphetamine) are widely abused in Spanish society. We present here the results of a systematic study of all cases of deaths brought to the attention of the Madrid department of the Instituto Nacional de Toxicologia from 1993 to 1995 in which some of these drugs have been found in the cadaveric blood. The cases were divided into three categories: amphetamine and derivatives, amphetamines and alcohol, amphetamines and other drugs. Data on age, sex, clinical symptoms, morphological findings, circumstances of death, when known, and concentration of amphetamine derivatives, alcohol and other drugs in blood are given for each group. The information provided here may prove to be useful for the forensic interpretation of deaths which are directly or indirectly related to abuse of amphetamine derivatives.

  16. Investigation - Derived Waste Program

    International Nuclear Information System (INIS)

    Beardsley, C.; Anderson, R.

    1998-06-01

    The Investigation-Derived Waste Program is a software application that was developed to identify the groundwater monitoring wells at the Savannah River Site that require containerization and treatment for purge water generated during sampling

  17. Histórico, tendências e perspectivas no planejamento espacial de usinas hidrelétricas brasileiras: a antiga e atual fronteira Amazônica

    Directory of Open Access Journals (Sweden)

    Evandro Mateus Moretto

    2012-12-01

    Full Text Available Os empreendimentos hidrelétricos são alternativas favoráveis economicamente em função do grande potencial hidrelétrico disponível no território brasileiro. Apesar de serem notórias em causar significativa degradação ambiental, conformam historicamente uma importante controvérsia do setor energético brasileiro. Orientado por esta problemática, o presente trabalho tem como objetivo principal analisar o histórico e as tendências do planejamento espacial de usinas hidrelétricas no Brasil, interpretando-os a partir da relação entre o potencial hidrelétrico disponível no espaço e o grau de disciplinamento do uso e ocupação do espaço no tempo. Até a década de 1970, a implantação de hidrelétricas ocorreu, relativamente, à luz de menor grau de disciplinamento de uso e ocupação do espaço, como foi o caso das hidrelétricas de Balbina e Tucuruí, as quais também induziram a primeira grande crise ambiental do setor e favoreceram a criação dos instrumentos de política ambiental, em 1981. As décadas de 1980 e 1990 são caracterizadas por um vazio de planejamento de hidrelétricas, o que é retomado a partir de 2000 em função de um ambiente econômico internacional favorável aos investimentos em infraestrutura, resultando no aumento da exploração do potencial hidrelétrico orientada especialmente para a região Amazônica. Porém, esta reorientação depara-se com um maior grau de disciplinamento do uso do espaço que acaba vinculando novas dimensões para o planejamento espacial de hidrelétricas, especialmente em regiões com alta sensibilidade socioambiental, como é o caso da Amazônica. Ainda assim, esta região é aquela que ainda detêm o maior potencial hidrelétrico a ser explorado, o que faz dela a escolhida como a fronteira hidrelétrica da década de 2010.Las usinas hidroelétricas representam una alternativa económica favorable debido el potencial hídrico de generación disponible en el territorio

  18. Tendência secular da doença respiratória na infância na cidade de São Paulo (1984-1996

    Directory of Open Access Journals (Sweden)

    Maria Helena D'Aquino Benicio

    2000-12-01

    Full Text Available OBJETIVO: Estimar a prevalência e a distribuição social da doença respiratória na infância, estabelecer a tendência secular dessa enfermidade e analisar sua determinação, com base nos dados coletados por dois inquéritos domiciliares realizados na cidade de São Paulo, SP, em 1984/85 e em 1995/96. MÉTODOS: Os inquéritos estudaram amostras probabilísticas da população residente na cidade com idades entre zero e 59 meses (1.016 em 1984/85 e 1.280 em 1995/96. Nos dois inquéritos estimou-se a prevalência instantânea da doença respiratória alta (acima da epiglote e da doença respiratória baixa com e sem chiado à ausculta pulmonar. A ocorrência da doença respiratória foi aferida por exames clínicos realizados em dias aleatórios, nos próprios domicílios das crianças, por médicos pediatras devidamente treinados e padronizados quanto ao diagnóstico da doença. Os exames clínicos incluíam a anamnese do dia, antecedentes de doença respiratória e o exame físico completo da criança, incluindo inspeção da orofaringe, otoscopia e ausculta pulmonar. Nos dois inquéritos, os exames foram distribuídos ao longo de um período de cerca de 12 meses, de modo a garantir uma varredura uniforme das várias áreas da cidade ao longo das quatro estações. O estudo da distribuição social da doença respiratória levou em conta tercis da renda familiar per capita em cada um dos inquéritos. A estratégia analítica para estudar os determinantes da evolução da prevalência da doença na população empregou modelos hierárquicos de causalidade, análises multivariadas de regressão e procedimentos análogos aos utilizados para calcular riscos atribuíveis populacionais. RESULTADOS/CONCLUSÕES: Houve entre os inquéritos aumentos expressivos na prevalência instantânea da doença respiratória alta (de 22,2% para 38,8% e da doença respiratória baixa sem e com chiado (de 6,0% para 10,0% e de 0,8% para 2,8%, respectivamente. No

  19. Development of Derivatives Reporting

    OpenAIRE

    Pejčochová, Kristina

    2012-01-01

    This thesis aims to summarise the theoretical principles, concepts and considerations pertaining to accounting for and reporting of derivatives and to describe and analyse the development of major accounting standards dealing with related issues. Sections 1 and 2 provide a basic overview of derivative instruments'categorisation, mechanics, valuation and uses. Section 3 studies the principles that ensure the provision of useful financial information, with specific focus on financial instrument...

  20. On higher derivative gravity

    International Nuclear Information System (INIS)

    Accioly, A.J.

    1987-01-01

    A possible classical route conducting towards a general relativity theory with higher-derivatives starting, in a sense, from first principles, is analysed. A completely causal vacuum solution with the symmetries of the Goedel universe is obtained in the framework of this higher-derivative gravity. This very peculiar and rare result is the first known vcuum solution of the fourth-order gravity theory that is not a solution of the corresponding Einstein's equations.(Author) [pt

  1. Brain derived neurotrophic factor

    DEFF Research Database (Denmark)

    Mitchelmore, Cathy; Gede, Lene

    2014-01-01

    Brain Derived Neurotrophic Factor (BDNF) is a neurotrophin with important functions in neuronal development and neuroplasticity. Accumulating evidence suggests that alterations in BDNF expression levels underlie a variety of psychiatric and neurological disorders. Indeed, BDNF therapies are curre......Brain Derived Neurotrophic Factor (BDNF) is a neurotrophin with important functions in neuronal development and neuroplasticity. Accumulating evidence suggests that alterations in BDNF expression levels underlie a variety of psychiatric and neurological disorders. Indeed, BDNF therapies...

  2. Gorenstein derived functions

    DEFF Research Database (Denmark)

    Holm, Henrik Granau

    2004-01-01

    Over any associative ring R it is standard to derive HomR(􀀀;􀀀) using projective resolutions in the rst variable, or injective resolutions in the second variable, and doing this, one obtains Extn R(􀀀;􀀀) in both cases. We examine the situation where projective...... and injective modules are replaced by Gorenstein projective and Gorenstein injective ones, respectively. Furthermore, we derive the tensor product 􀀀 R 􀀀 using Gorenstein at modules....

  3. Terminology for Neuroscience Data Discovery: Multi-tree Syntax and Investigator-Derived Semantics

    Science.gov (United States)

    Goldberg, David H.; Grafstein, Bernice; Robert, Adrian; Gardner, Esther P.

    2009-01-01

    The Neuroscience Information Framework (NIF), developed for the NIH Blueprint for Neuroscience Research and available at http://nif.nih.gov and http://neurogateway.org, is built upon a set of coordinated terminology components enabling data and web-resource description and selection. Core NIF terminologies use a straightforward syntax designed for ease of use and for navigation by familiar web interfaces, and readily exportable to aid development of relational-model databases for neuroscience data sharing. Datasets, data analysis tools, web resources, and other entities are characterized by multiple descriptors, each addressing core concepts, including data type, acquisition technique, neuroanatomy, and cell class. Terms for each concept are organized in a tree structure, providing is-a and has-a relations. Broad general terms near each root span the category or concept and spawn more detailed entries for specificity. Related but distinct concepts (e.g., brain area and depth) are specified by separate trees, for easier navigation than would be required by graph representation. Semantics enabling NIF data discovery were selected at one or more workshops by investigators expert in particular systems (vision, olfaction, behavioral neuroscience, neurodevelopment), brain areas (cerebellum, thalamus, hippocampus), preparations (molluscs, fly), diseases (neurodegenerative disease), or techniques (microscopy, computation and modeling, neurogenetics). Workshop-derived integrated term lists are available Open Source at http://brainml.org; a complete list of participants is at http://brainml.org/workshops. PMID:18958630

  4. Asia Pacific energy derivatives

    International Nuclear Information System (INIS)

    Fusaro, P.C.

    1997-09-01

    Asia Pacific Energy Derivatives, from FT Energy, is the first report of its kind to examine the growth of energy derivatives within Asia Pacific and their increasing importance within this region. It provides a comprehensive overview of the subject, including analysis of: deregulation as a market driver; the impact of privatisation; the future for energy risk management tools; the unique characteristics of the Asia Pacific energy market; the role of futures exchanges in Asia; existing indexes and their performance; the differences between the Asia Pacific markets and their more mature counterparts in London and New York; non-oil derivatives, project finance and cross commodity arbitrage; the thriving Pacific Rim Over the Counter (OTC) markets. (author)

  5. 4-Aminoquinoline derivatives

    DEFF Research Database (Denmark)

    Singh, Shailja; Agarwal, Drishti; Sharma, Kumkum

    2016-01-01

    and found them to be effective against Plasmodium falciparum under in vitro conditions. Further, we selected four most active derivatives 1m, 1o, 2c and 2j and evaluated their antimalarial potential against Plasmodium berghei in vivo. These 4-aminoquinolines cured BALB/c mice infected with P. berghei......Synthetic quinoline derivatives continue to be considered as candidates for new drug discovery if they act against CQ-resistant strains of malaria even after the widespread emergence of resistance to CQ. In this study, we explored the activities of two series of new 4-aminoquinoline derivatives...... for structure activity relationship to find lead molecules for treating multidrug-resistant Plasmodium falciparum and Plasmodium vivax....

  6. Essays on Derivatives Pricing

    DEFF Research Database (Denmark)

    Kokholm, Thomas

    . With the existence of a liquid market for derivatives with variance as underlying, such as VIX options, VIX futures and a well-developed over-the-counter market for options on variance swaps, it is important to consider models that are able to fit these markets while consistently pricing vanilla options...... financial models, and most importantly, to be aware of their limitations. Following that belief, this thesis consists of three independent and self-contained papers, all dealing with topics in derivatives pricing. The first paper considers the pricing of traffic light options, which are appropriate...... the market for multivariate credit instruments, we take a step back and focus on single-name default modeling and introduce two new model classes for modeling of the default time of a company. Finally, in the third paper we propose a consistent pricing model for index and volatility derivatives...

  7. Competência Informacional: análise evolucionária das tendências da pesquisa e produtividade científica em âmbito mundial

    OpenAIRE

    Dudziak, Elisabeth Adriana; Universidade de Sao Paulo

    2010-01-01

    Objetiva analisar a produtividade científica e identificar tendências de pesquisa em torno do tema da competência informacional (information literacy), tomando por base pesquisa reali-zada em duas das principais bases de dados internacionais multidisciplinares dedicadas à análise de citações: Web of Science (WoS) e SCOPUS. Inicia abordando o significado da análise bibliométrica e sua importância na determinação de tendências da atividade e produ-tividade científicas. Apresenta a evolução do c...

  8. Cambios Morfológicos en la Regeneración del Tendón Calcáneo de Rata (Sprague Dawley) por la Aplicación de Ultrasonido Continuo

    OpenAIRE

    Schencke, Carolina; del Sol, Mariano

    2010-01-01

    Las lesiones de los tendones plantean siempre grandes problemas clínicos y terapéuticos, por su importancia funcional y su peculiar cicatrización. El apoyo fisiátrico, específicamente el tratamiento con ultrasonido, ha demostrado ser eficiente en la regeneración del tendón calcáneo. Este trabajo tuvo como objetivo analizar morfológicamente los efectos del uso de ultrasonido continuo en la regeneración post quirúrgica del tendón calcáneo de rata. Se utilizaron 15 ratas albinas, Sprager Dawle. ...

  9. Efeitos da laserterapia de baixa potência associada ou não a exercício excêntrico no tratamento de tendinopatia induzida do tendão calcanear comum de Ratos (Rattus norvegicus)

    OpenAIRE

    Silva, Micheline Ozana da

    2013-01-01

    A dissertação foi desenvolvida em dois subprojetos, sendo o primeiro intitulado Análises clínica e biomecânica do tendão calcanear comuns de ratos Wistar submetido à laserterapia associada ou não a exercício excêntrico , e o segundo Análise histomorfometrica do tendão calcanear comum de ratos Wistar tratado com laserterapia e exercício excêntrico . O primeiro subprojeto teve como objetivo avaliar o efeito da terapia com laser de baixa potência associada a exercício excêntrico (caminhada em ...

  10. The combinatorial derivation

    Directory of Open Access Journals (Sweden)

    Igor V. Protasov

    2013-09-01

    $\\Delta(A=\\{g\\in G:|gA\\cap A|=\\infty\\}$. The mapping $\\Delta:\\mathcal{P}_G\\rightarrow\\mathcal{P}_G$, $A\\mapsto\\Delta(A$, is called a combinatorial derivation and can be considered as an analogue of the topological derivation $d:\\mathcal{P}_X\\rightarrow\\mathcal{P}_X$, $A\\mapsto A^d$, where $X$ is a topological space and $A^d$ is the set of all limit points of $A$. Content: elementary properties, thin and almost thin subsets, partitions, inverse construction and $\\Delta$-trajectories,  $\\Delta$ and $d$.

  11. Quinazolin-4-one derivatives

    DEFF Research Database (Denmark)

    Mosley, Cara A; Acker, Timothy M; Hansen, Kasper Bø

    2010-01-01

    We describe a new class of subunit-selective antagonists of N-methyl D-aspartate (NMDA)-selective ionotropic glutamate receptors that contain the (E)-3-phenyl-2-styrylquinazolin-4(3H)-one backbone. The inhibition of recombinant NMDA receptor function induced by these quinazolin-4-one derivatives...

  12. Metal borohydrides and derivatives

    DEFF Research Database (Denmark)

    Paskevicius, Mark; Haarh Jepsen, Lars; Schouwink, Pascal

    2017-01-01

    major classes of metal borohydride derivatives have also been discovered: anion-substituted compounds where the complex borohydride anion, BH4 -, is replaced by another anion, i.e. a halide or amide ion; and metal borohydrides modified with neutral molecules, such as NH3, NH3BH3, N2H4, etc. Here, we...

  13. 78 FR 32191 - Derivatives

    Science.gov (United States)

    2013-05-29

    ... rate risk. This proposed rule applies to federal credit unions and any federally insured, state... risk to the National Credit Union Share Insurance Fund (NCUSIF). \\1\\ A derivative is an instrument... degrees of risk to a credit union. Accordingly, this risk calls for a more robust asset/ liability...

  14. Superstability of Generalized Derivations

    Directory of Open Access Journals (Sweden)

    Esmaeil Ansari-Piri

    2010-01-01

    Full Text Available We investigate the superstability of the functional equation f(xy=xf(y+g(xy, where f and g are the mappings on Banach algebra A. We have also proved the superstability of generalized derivations associated to the linear functional equation f(γx+βy=γf(x+βf(y, where γ,β∈ℂ.

  15. Approximate *-derivations and approximate quadratic *-derivations on C*-algebras

    Directory of Open Access Journals (Sweden)

    Park Choonkil

    2011-01-01

    Full Text Available Abstract In this paper, we prove the stability of *-derivations and of quadratic *-derivations on Banach *-algebras. We moreover prove the superstability of *-derivations and of quadratic *-derivations on C*-algebras. 2000 Mathematics Subject Classification: 39B52; 47B47; 46L05; 39B72.

  16. Derived enriched uranium market

    International Nuclear Information System (INIS)

    Rutkowski, E.

    1996-01-01

    The potential impact on the uranium market of highly enriched uranium from nuclear weapons dismantling in the Russian Federation and the USA is analyzed. Uranium supply, conversion, and enrichment factors are outlined for each country; inventories are also listed. The enrichment component and conversion components are expected to cause little disruption to uranium markets. The uranium component of Russian derived enriched uranium hexafluoride is unresolved; US legislation places constraints on its introduction into the US market

  17. Computation of Mie derivatives.

    Science.gov (United States)

    Li, Yang; Bowler, Nicola

    2013-07-10

    Analytical expressions are obtained for the derivatives of Mie scattering coefficients with respect to the electrical radius of the spherical scattering particle, and to the relative permittivity and permeability of both the particle and the surrounding medium. Their corresponding approximate expressions are developed to avoid numerical overflow based on the logarithmic derivative of Riccati-Bessel functions. The analytical expressions have been verified by comparing their results with those calculated by analytical expressions developed by Mathematica. Compared with the numerical derivative, the analytical expressions and approximate expressions show a higher accuracy and are 2.0 and 2.8 times, respectively, faster in the case of a single magnetodielectric sphere. Generally, for spheres with an electrical radius in a large range, the approximate expressions can yield acceptable accuracy and computation time up to a high order. This work can be used in the design of nonmetallic metamaterials, and in the retrieval of aerosol properties from remote sensing data. An example calculation is given for the design of an optical, all-dielectric, mu-negative metamaterial consisting of a simple cubic array of tellurium nanoparticles.

  18. Carnitine derivatives: clinical usefulness.

    Science.gov (United States)

    Malaguarnera, Mariano

    2012-03-01

    Carnitine and its derivatives are natural substances involved in both carbohydrate and lipid metabolism. This review summarizes the recent progress in the field in relation to the molecular mechanisms. The pool of different carnitine derivatives is formed by acetyl-L-carnitine (ALC), propionyl-L-carnitine (PLC), and isovaleryl-carnitine. ALC may have a preferential effect on the brain tissue. ALC represents a compound of great interest for its wide clinical application in various neurological disorders: it may be of benefit in treating Alzheimer's dementia, depression in the elderly, HIV infection, chronic fatigue syndrome, peripheral neuropathies, ischemia and reperfusion of the brain, and cognitive impairment associated with various conditions. PLC has been demonstrated to replenish the intermediates of the tricarboxylic acid cycle by the propionyl-CoA moiety, a greater affinity for the sarcolemmal carrier, peripheral vasodilator activity, a greater positive inotropism, and more rapid entry into myocytes. Most studies of the therapeutic use of PLC are focused on the prevention and treatment of ischemic heart disease, congestive heart failure, hypertrophic heart disease, and peripheral arterial disease. ALC and PLC are considered well tolerated without significant side-effects. A number of therapeutic effects possibly come from the interaction of carnitine and its derivatives with the elements of cellular membranes.

  19. Multifunctional Cinnamic Acid Derivatives

    Directory of Open Access Journals (Sweden)

    Aikaterini Peperidou

    2017-07-01

    Full Text Available Our research to discover potential new multitarget agents led to the synthesis of 10 novel derivatives of cinnamic acids and propranolol, atenolol, 1-adamantanol, naphth-1-ol, and (benzylamino ethan-1-ol. The synthesized molecules were evaluated as trypsin, lipoxygenase and lipid peroxidation inhibitors and for their cytotoxicity. Compound 2b derived from phenoxyphenyl cinnamic acid and propranolol showed the highest lipoxygenase (LOX inhibition (IC50 = 6 μΜ and antiproteolytic activity (IC50 = 0.425 μΜ. The conjugate 1a of simple cinnamic acid with propranolol showed the higher antiproteolytic activity (IC50 = 0.315 μΜ and good LOX inhibitory activity (IC50 = 66 μΜ. Compounds 3a and 3b, derived from methoxylated caffeic acid present a promising combination of in vitro inhibitory and antioxidative activities. The S isomer of 2b also presented an interesting multitarget biological profile in vitro. Molecular docking studies point to the fact that the theoretical results for LOX-inhibitor binding are identical to those from preliminary in vitro study.

  20. Credit derivatives and risk management

    OpenAIRE

    Michael S. Gibson

    2007-01-01

    The striking growth of credit derivatives suggests that market participants find them to be useful tools for risk management. I illustrate the value of credit derivatives with three examples. A commercial bank can use credit derivatives to manage the risk of its loan portfolio. An investment bank can use credit derivatives to manage the risks it incurs when underwriting securities. An investor, such as an insurance company, asset manager, or hedge fund, can use credit derivatives to align its...

  1. Credit derivatives in emerging markets

    OpenAIRE

    Romain Rancière

    2002-01-01

    Credit Derivatives are securities that offer protection against credit or default risk of bonds or loans. The credit derivatives emerging market has grown rapidly and credit derivatives are widely used. This paper describes the emerging credit derivatives market structure. The current market activity is analyzed through elementary pricing dynamics and the study of the term structure of default risk. Focusing on the performance of credit derivatives in stress situation, including legal and mar...

  2. Tending to Student and Family Health

    Science.gov (United States)

    Green, Erin

    2012-01-01

    Without a doubt, the economy is taking its toll on families, many of whom face reduced wages, unemployment, foreclosure, and decreased--or nonexistent--health care benefits. With this in mind, the Greendale Schools' director of pupil services and this author wondered whether they could offer the Employee Assistance Program (EAP), which is designed…

  3. Tending the tensions in co-creation

    DEFF Research Database (Denmark)

    Phillips, Professor MSO Louise; Nordentoft, Helle Merete; Pedersen, Lektor Christina Hee

    -for-granted positive value. In the panel we de-romanticise “co-creation” and explore how it is enacted in particular organisational contexts, concentrating on context-specific tensions arising in the meeting between different knowledge forms and interests. These include tensions BETWEEN dialogic views of knowledge co-creation...

  4. Efeitos de um programa de reabilitação acelerado após o tratamento cirúrgico da ruptura aguda do tendão de Aquiles

    OpenAIRE

    Ott, Rafael Duvelius

    2010-01-01

    Objetivo: Avaliar os efeitos de um protocolo acelerado de reabilitação (ACE) versus um protocolo tradicional de imobilização do tornozelo (TRA) sobre a função muscular e articular, após o tratamento cirúrgico da ruptura aguda do tendão de Aquiles. Método: 37 pacientes com diagnóstico de ruptura aguda do tendão de Aquiles foram submetidos ao tratamento cirúrgico aberto com reparo término-terminal pela técnica de Krackow. Após a cirurgia, foram divididos em dois grupos: no grupo ACE foi utiliza...

  5. Comportamento mecânico de tendões calcâneo bovino sob informações clínicas Mechanical behaviour of bovine calcaneous tendon under ciclic deformations

    Directory of Open Access Journals (Sweden)

    Sergio Rocha Piedade

    2006-02-01

    Full Text Available Este trabalho teve por finalidade analisar o comportamento de tendões calcâneo bovino submetidos a ensaios mecânicos cíclicos. Para cada corpo de prova foram aplicados três ensaios de dez ciclos de tração e três níveis de deformação: 2,5%, 3% e 4%. Ao término de cada ensaio o tendão era mantido em repouso por 300 s. A velocidade de carregamento adotada foi de 10% do comprimento do corpo de prova, por segundo. Os resultados obtidos foram submetidos à análise de variância com delineamento de parcelas subdivididas no tempo e blocos casualizados nas subparcelas. Conclui-se que o pré-tensionamento de tendões realizado através da deformação relativa permanece como parâmetro mais seguro, por atuar dentro dos limites fisiológicos do tendão, evitando os efeitos nocivos do sobretensionamento.This research work reports an experimental study on the mechanical behavior of bovine calcaneous tendons. A total number of 03 cyclic relaxation tests with 10 cycles respectively at 2,5%, 3%, and 4% of deformation were performed for each specimen. The specimens were kept at rest for 300 s between tests. Deformation rates were maintained at 10% of initial length per second. Cyclic relaxation tests carried on all tendons showed that the average force correspondent to the first cycle was statistically significatively greater than the average force correspondent to the tenth cycle. This also emphasizes the occurrence of a force relaxation phenomena. It can be concluded that tendons pre-tensionning by means of specific deformations stands for a safer parameter because it acts within the tendon biological limits avoyding the overtensioning negative effects.

  6. Avaliação biomecânica dos tendões dos músculos tibiais e proposta de sua utilização como aloenxertos nas reconstruções do ligamento cruzado anterior

    Directory of Open Access Journals (Sweden)

    Viegas Alexandre de Christo

    2003-01-01

    Full Text Available Com o objetivo de avaliar as propriedades mecânicas dos tendões dos músculos tibial anterior (TA e tibial posterior (TP, o autor realizou ensaios mecânicos com tendões extraídos de 18 cadáveres humanos frescos, do sexo masculino, com média de idade de 45,2 ± 10,7 anos. Os tendões foram divididos em dois grupos e armazenados a -20°C e a -86°C durante 30 a 90 dias antes dos testes. Depois de descongelados, foram feitas medidas da área de secção transversa dos tendões e ensaios mecânicos de tração até a ruptura a uma velocidade de aplicação de carga de 20 mm/min. Foram determinadas as seguintes propriedades biomecânicas: resistência máxima, coeficiente de rigidez, módulo de elasticidade e alongamento máximo relativo; os dados obtidos foram comparados aos existentes na literatura relativos ao ligamento cruzado anterior (LCA e seus substitutos mais utilizados. A comparação dos dados obtidos neste estudo com os estudos biomecânicos feitos por outros autores nos permitiu observar que o TA e o TP apresentam propriedades mecânicas que os tornam possíveis substitutos do LCA nos casos em que a necessidade de enxertos alógenos se impuser.

  7. In defense of derivations

    Science.gov (United States)

    Mungan, Carl E.

    2016-05-01

    At the 2015 AAPT Summer Meeting, I presented four derivations of the formula for motional emf. Such physics derivations involve the construction of explanatory frameworks involving diagrams and mathematical models. Although textbooks devote considerable space to such explanations, many teachers and students spend their time on worksheets, end-of-chapter problems, and the like. The book is reduced to a bank of solved (i.e., example) and unsolved (i.e., homework) questions, along with equations in colored boxes that presumably are to be used to answer those questions. Such an approach encourages fragmentation of knowledge, the view that there is only one right answer to a problem with the goal of physics being to find that answer (neatly boxed of course), and the inability to reason about even a slightly different (much less a novel) situation. If we are to develop scientific literacy, significant course time must be devoted to explaining the structure of and support for the models and equations we use.

  8. 6-Bromocholesterol derivatives

    International Nuclear Information System (INIS)

    Flanagan, R.J.

    1984-01-01

    Novel 6-bromo derivatives of cholesterol have the formula 3-(R-O-),6-BR,17-((H3C-)2-HC-H2C-H2C-H2C-HC(-CH3)-)-ESTR-5-ENE Such compounds are prepared from the known 6-iodocholesterol by treatment with cuprous bromide. These compounds, labelled with radioisotopes of Br-82 or Br-77, are localized in the adrenal, mammary and ovary tissue of female mammals and in the adrenal or prostate tissue of males when administered to such individuals. This provides a method for imaging adrenal, ovary or prostate tissue which is superior to use of the prior art 6-iodo-cholesterol

  9. Algae Derived Biofuel

    Energy Technology Data Exchange (ETDEWEB)

    Jahan, Kauser [Rowan Univ., Glassboro, NJ (United States)

    2015-03-31

    One of the most promising fuel alternatives is algae biodiesel. Algae reproduce quickly, produce oils more efficiently than crop plants, and require relatively few nutrients for growth. These nutrients can potentially be derived from inexpensive waste sources such as flue gas and wastewater, providing a mutual benefit of helping to mitigate carbon dioxide waste. Algae can also be grown on land unsuitable for agricultural purposes, eliminating competition with food sources. This project focused on cultivating select algae species under various environmental conditions to optimize oil yield. Membrane studies were also conducted to transfer carbon di-oxide more efficiently. An LCA study was also conducted to investigate the energy intensive steps in algae cultivation.

  10. SEMANTIC DERIVATION OF BORROWINGS

    Directory of Open Access Journals (Sweden)

    Shigapova, F.F.

    2017-09-01

    Full Text Available The author carried out the contrastive analysis of the word спикер borrowed into Russian from English and the English word speaker. The findings of the analysis include confirm (1 different derivational abilities and functions of the borrowed word and the native word; (2 distinctive features in the definitions, i.e. semantic structures, registered in monolingual non-abridged dictionaries; (3 heterogeneous parameters of frequencies recorded in the National Corpus of the Russian language and the British National Corpus; (4 absence of bilingual equivalent collocations with words спикер and speaker. The collocations with words studied revealed new lexical and connotative senses in the meaning of the word. Relevance of the study conducted is justified by the new facts revealed about the semantic adaptation of the borrowed word in the system of the Russian language and its paradigmatic and syntagmatic connections in the system of the recipient language.

  11. Original and Derived Judgment

    DEFF Research Database (Denmark)

    Foss, Kirsten; Foss, Nicolai Juul; Klein, Peter G.

    2007-01-01

    Recent work links entrepreneurship to the economic theory of the firm, using the concept of entrepreneurship as judgment introduced by Frank Knight. When judgment is complementary to other assets, it makes sense for entrepreneurs to hire labour and to own assets. The entrepreneur's role, then...... to subordinates, who exercise derived judgment. We call these employees `proxy-entrepreneurs', and ask how the firm's organizational structure - its formal and informal systems of rewards and punishments, rules for settling disputes and renegotiating agreements, means of evaluating performance and so on - can...... be designed to encourage forms of proxy entrepreneurship that increase firm value while discouraging actions that destroy value. Building on key ideas from the entrepreneurship literature, Austrian economics and the economic theory of the firm, we develop a framework for analysing the trade-off between...

  12. Soybean-derived biofuels and home heating fuels.

    Science.gov (United States)

    Mushrush, George W; Wynne, James H; Willauer, Heather D; Lloyd, Christopher L

    2006-01-01

    It is environmentally enticing to consider replacing or blending petroleum derived heating fuels with biofuels for many reasons. Major considerations include the soaring worldwide price of petroleum products, especially home heating oil, the toxicity of the petroleum-derived fuels and the environmental damage that leaking petroleum tanks afford. For these reasons, it has been suggested that domestic renewable energy sources be considered as replacements, or at the least, as blending stocks for home heating fuels. If recycled soy restaurant cooking oils could be employed for this purpose, this would represent an environmental advantage. Renewable plant sources of energy tend to be less toxic than their petroleum counterparts. This is an important consideration when tank leakage occurs. Home fuel oil storage tanks practically always contain some bottom water. This water environment has a pH value that factors into heating fuel stability. Therefore, the question is: would the biofuel help or exacerbate fuel stability and furnace maintenance issues?

  13. A estrutura e a tendência evolutiva da carga externa em paralelas assimétricas. Análise das rotações em exercícios de competição

    OpenAIRE

    Ferreirinha, José; Silva, António; Marques, António

    2008-01-01

    Embora a Ginástica Artística seja muitas vezes referida como uma modalidade associada a grandes volumes e intensidades de treino são escassos os dados recolhidos da literatura objectivamente mensurados, que fundamentem tais referências. Com este estudo procurámos caracterizar e avaliar as tendências da carga externa de um exercício de paralelas assimétricas de alto rendimento, com base na análise das rotações sobre o eixo transversal e longitudinal. Recorrendo às técnicas da metodologia obser...

  14. Presència, tendències i aspectes diferenciadors de la formació sobre drets d'autor en l'alfabetització informacional en l'àmbit universitari

    OpenAIRE

    Uribe Tirado, Alejandro

    2010-01-01

    Objectiu. Analitzar la presència de la temàtica dels drets d'autor, dels aspectes legals de la informació acadèmica i científica, en diferents programes, cursos o programes d'aprenentatge d'alfabetització informacional (ALFIN) de diferents universitats al voltant del món, per identificar les tendències i aspectes diferenciadors que es presenten actualment respecte a la formació en aquestes temàtiques en relació amb la informació digital. També s'analitza com de preparades estan les comunitats...

  15. Alterações no tendão de Aquiles após inflamação em tecido adjacente Alterations in the Achilles tendon after inflammation in surrounding tissue

    Directory of Open Access Journals (Sweden)

    Cristiano Pedrozo Vieira

    2012-01-01

    Full Text Available OBJETIVO: Analisar as características de tendões de Aquiles de ratos após indução de processo inflamatório localizado na pata. MÉTODOS: Foram utilizados três grupos experimentais: grupo inflamado com carragenina na pata de rato (G1; grupo salina (G2 e grupo controle (G3. Após 4 horas os animais foram eutanaziados e o tendão de Aquiles foi removido. RESULTADOS:Não foram observadas diferenças significativas nas análises de proteínas não colagênicas, glicosaminoglicanos e hidroxiprolina, mas uma tendência a diminuição foi verificada em G1. Em organização de moléculas de colágeno não foram observadas diferenças entre os grupos. Com respeito à atividade de MMPs, foi observada uma presença maior da isoforma ativa da MMP-2 em G1, sugerindo que a remodelação do tecido está ocorrendo. CONCLUSÃO: Desta forma, nós concluímos que o processo inflamatório desencadeado em pata de rato pode afetar o remodelamento de tendões situados próximo ao local inflamado. Nível de Evidência I, Estudos Prognósticos - Investigação do Efeito de Característica de um Paciente Sobre o Desfecho da Doença.OBJECTIVE: To analyze the characteristics of the Achilles tendon of rats after induction of localized inflammation in the rat paw. METHODS: In our study three groups were used: inflamed group with carrageenan in rat paw (G1; saline group (G2 and control group (G3. After 4 hours the animals were euthanized and the Achilles tendon removed. RESULTS: No significant differences were observed in the analysis of non-collagenous proteins, glycosaminoglycans and hydroxyproline in the groups but a tendency of reduction was verified in G1. About the organization of collagen molecules, no differences were observed between groups. With respect to MMPs activity, a stronger presence of the active isoform of MMP-2 in G1 was observed, suggesting that the remodeling was occurring. CONCLUSION: Thus, we conclude that the inflammatory process in rat paw may

  16. Tendências de pesquisas brasileiras sobre mulheres mastectomizadas Tendencias en la investigación sobre la mujer brasileña sometida a mastectomía Trends in research with Brazilian women after mastectomy

    OpenAIRE

    Elisângela Braga de Azevedo; Pollyana Amorim Ponce de Leon Bezerra; José Melquiades Ramalho Neto; Leila Alcina Correia Vaz Bustorff; Cláudia Maria Ramos Medeiros Souto

    2012-01-01

    Objetivou-se analisar as tendências das pesquisas realizadas no Brasil sobre mulheres mastectomizadas. Trata-se de um estudo bibliográfico de abordagem quantitativa, realizado de 15 de junho a 31 de julho de 2009. Para coleta dos dados empíricos utilizou-se um instrumento estruturado, posteriormente os dados foram tabulados, analisados, transformados em porcentagens e agrupados em uma tabela para facilitar a visualização das informações. A amostra foi constituída por resumos adquiridos atravé...

  17. Piroxicam derivatives THz classification

    Science.gov (United States)

    Sterczewski, Lukasz A.; Grzelczak, Michal P.; Nowak, Kacper; Szlachetko, Bogusław; Plinska, Stanislawa; Szczesniak-Siega, Berenika; Malinka, Wieslaw; Plinski, Edward F.

    2016-02-01

    In this paper we report a new approach to linking the terahertz spectral shapes of drug candidates having a similar molecular structure to their chemical and physical parameters. We examined 27 newly-synthesized derivatives of a well-known nonsteroidal anti-inflammatory drug Piroxicam used for treatment of inflammatory arthritis and chemoprevention of colon cancer. The testing was carried out by means of terahertz pulsed spectroscopy (TPS). Using chemometric techniques we evaluated their spectral similarity in the terahertz range and attempted to link the position on the principal component analysis (PCA) score map to the similarity of molecular descriptors. A simplified spectral model preserved 75% and 85.1% of the variance in 2 and 3 dimensions respectively, compared to the input 1137. We have found that in 85% of the investigated samples a similarity of the physical and chemical parameters corresponds to a similarity in the terahertz spectra. The effects of data preprocessing on the generated maps are also discussed. The technique presented can support the choice of the most promising drug candidates for clinical trials in pharmacological research.

  18. Experts' understanding of partial derivatives using the Partial Derivative Machine

    OpenAIRE

    Roundy, David; Dorko, Allison; Dray, Tevian; Manogue, Corinne A.; Weber, Eric

    2014-01-01

    Partial derivatives are used in a variety of different ways within physics. Most notably, thermodynamics uses partial derivatives in ways that students often find confusing. As part of a collaboration with mathematics faculty, we are at the beginning of a study of the teaching of partial derivatives, a goal of better aligning the teaching of multivariable calculus with the needs of students in STEM disciplines. As a part of this project, we have performed a pilot study of expert understanding...

  19. Design of two-channel filter bank using nature inspired optimization based fractional derivative constraints.

    Science.gov (United States)

    Kuldeep, B; Singh, V K; Kumar, A; Singh, G K

    2015-01-01

    In this article, a novel approach for 2-channel linear phase quadrature mirror filter (QMF) bank design based on a hybrid of gradient based optimization and optimization of fractional derivative constraints is introduced. For the purpose of this work, recently proposed nature inspired optimization techniques such as cuckoo search (CS), modified cuckoo search (MCS) and wind driven optimization (WDO) are explored for the design of QMF bank. 2-Channel QMF is also designed with particle swarm optimization (PSO) and artificial bee colony (ABC) nature inspired optimization techniques. The design problem is formulated in frequency domain as sum of L2 norm of error in passband, stopband and transition band at quadrature frequency. The contribution of this work is the novel hybrid combination of gradient based optimization (Lagrange multiplier method) and nature inspired optimization (CS, MCS, WDO, PSO and ABC) and its usage for optimizing the design problem. Performance of the proposed method is evaluated by passband error (ϕp), stopband error (ϕs), transition band error (ϕt), peak reconstruction error (PRE), stopband attenuation (As) and computational time. The design examples illustrate the ingenuity of the proposed method. Results are also compared with the other existing algorithms, and it was found that the proposed method gives best result in terms of peak reconstruction error and transition band error while it is comparable in terms of passband and stopband error. Results show that the proposed method is successful for both lower and higher order 2-channel QMF bank design. A comparative study of various nature inspired optimization techniques is also presented, and the study singles out CS as a best QMF optimization technique. Copyright © 2014 ISA. Published by Elsevier Ltd. All rights reserved.

  20. 2-Thiophenecarboxylic acid hydrazide Derivatives: Synthesis and Anti-Tuberculosis Studies

    Science.gov (United States)

    Fahmi, M. R. G.; Khumaidah, L.; Ilmiah, T. K.; Fadlan, A.; Santoso, M.

    2018-04-01

    One of the most frequent and widespread infectious diseases especially in developing countries is tuberculosis (TB). The number of TB drug resistant tend to increase, and there has been no new TB drug introduce since the 1960s. Six 2-Thiophenecarboxylic acid hydrazide derivatives were synthesized in 90-97% yields, and 2-thiophenecarbonylhydrazone-5, 7-dibromoisatin showed the highest activity in inhibiting M. tuberculosis H37Rv.

  1. Derivative spectrophotometry of cobalt alloys

    International Nuclear Information System (INIS)

    Spitsyn, P.K.

    1985-01-01

    The method of derivative spectrophotometry is briefly described, and derivative absorption spectra are presented for samarium, cobalt, and commercial Sm-Co alloys. It is shown that the use of derivative spectrophotometry not only improves the accuracy and selectivity of element determinations but also simplifies the analysis of alloys. Results of a statistical evaluation of the metrological characteristics of the analytical procedure described here are presented. 8 references

  2. Tendência empreendedora do gerente: uma análise de sua relevância para o sucesso de projetos inovadores Manager entrepreneur tendency: an analysis of its relevance to innovative projects success

    Directory of Open Access Journals (Sweden)

    Rosária de Fátima Segger Macri Russo

    2007-12-01

    Full Text Available O gerente de projeto, no seu papel de liderança, é um elemento-chave, tanto para o sucesso dos empreendimentos que coordena, quanto para a implementação das estratégias das organizações. Adicionalmente, pode se tornar importante para o futuro da organização, ao usar sua capacidade empreendedora para vislumbrar novas necessidades e oportunidades. No entanto, o gerente de projetos tem responsabilidades operacionais, de planejamento, monitoramento, contabilização e controle do projeto, que muitas vezes contrastam com as características de um empreendedor. Ante essas visões contraditórias sobre o gerente de projetos torna-se relevante avaliar se as características de um empreendedor quando incorporadas no perfil de um gerente se refletem em projetos mais bem sucedidos do ponto de vista empresarial. Para esta avaliação, foi feita uma pesquisa de campo com 164 gerentes de projetos, em sua maioria homens, com estudos de pós-graduação e bastante experientes. A análise não-paramétrica indicou uma tendência de se ter projetos mais bem sucedidos quanto maior for a tendência empreendedora do gerente de projetos. Houve um destaque para a tendência criativa, para a qual se pôde observar um impacto positivo sobre inúmeros critérios de sucesso.A project manager as a leader is the key element to assure the success of the ventures he/she is responsible for and to implement the organization strategies. Besides, the project manager can be very important to the future of the organization by applying entrepreneur skills aiming at needs and new opportunities. However, he/she has operational responsibilities such as planning, monitoring, and accounting and control of the project which can, some times, conflict with characteristics of an entrepreneur. Therefore, it is relevant to evaluate whether a project manager has the required entrepreneur skills which when combined the skills of a manger result in successful projects. In order to

  3. Tendência temporal de tabagismo em população urbana: um estudo de base populacional no Sul do Brasil Time trends in smoking in an urban population: a population-based study in Southern Brazil

    Directory of Open Access Journals (Sweden)

    Josiane L. Dias-Damé

    2011-11-01

    Full Text Available Avaliou-se a tendência temporal da prevalência de tabagismo conforme renda familiar, idade e sexo entre indivíduos com 20 anos ou mais residentes em Pelotas, Rio Grande do Sul, Brasil. Cinco inquéritos de base populacional utilizando-se de setores censitários foram realizados na cidade entre 2002-2010. Considerou-se tabagismo o consumo de um ou mais cigarros por dia há pelo menos um mês. A tendência temporal foi avaliada por meio do teste de qui-quadrado para tendência linear. Os cinco inquéritos realizados incluíram 15.136 indivíduos. Neste período, a prevalência total de tabagismo caiu de 28% (25,8-30,4 em 2002 para 21% (19,5-23,5 em 2010. Esta queda de 23% foi semelhante entre os sexos, mas muito diferente em relação à renda familiar. Quanto menor a renda familiar, maior a prevalência de tabagismo. Entre 2002-2010, a taxa de redução do tabagismo foi de 26% no menor quintil de renda e de 39% no maior. Apesar das reduções observadas, a prevalência de tabagismo ainda é elevada, indicando a necessidade de fortalecer medidas de controle voltadas principalmente aos indivíduos com menor renda.This study evaluated time trends in smoking prevalence according to gender and family income among individuals 20 years or older in Pelotas, Rio Grande do Sul State, Brazil. Five population-based surveys using census tracts were conducted in the city from 2002 to 2010. Smoking was defined as consumption of one or more cigarettes per day for at least one month. Time trend was assessed using the chi-square test for linear trend. 15,136 individuals were enrolled in these surveys. During this period, overall smoking prevalence decreased from 28% (25.8-30.4 in 2002 to 21% (19.5-23.5 in 2010. This 23% decline was similar in both genders, but differed significantly according to family income (smoking prevalence increased as income dropped. From 2002 to 2010, smoking decreased by 26% in the lowest income quintile and 39% in the highest. Despite

  4. Estudo da resistência do tendão do supra-espinal com pontos simples, duplos e Mason Allen Study on the resistance of the supraspinous tendon using simple, matress and mason allen stitches

    Directory of Open Access Journals (Sweden)

    Roberto Yukio Ikemoto

    2010-01-01

    Full Text Available OBJETIVO: O objetivo do trabalho foi comparar a resistência entre os pontos simples, duplo e Mason-Allen modificado, utilizados para o reparo do manguito rotador, e verificar se há diferença significativa que justifique a utilização do ponto do tipo Mason-Allen modificado ao invés dos pontos simples ou duplo. MÉTODO: Retiramos tendões do músculo supra-espinal de 15 cadáveres humanos frescos (30 ombros, com a média de idade de 45 anos. Os testes foram realizados na máquina universal de ensaio mecânico Kratos® 500/2000 e os resultados submetidos aos testes estatísticos de t-student, análise de variância (ANOVA, comparação múltipla de Bonferroni e calculadas as correlações de Pearson. Os testes foram realizados ao nível de significância de 5%. RESULTADOS: Não houve diferença significativa com relação à idade, ao tamanho das amostras e deslocamento do tendão. A resistência variou com média de 127,50 N com o ponto simples, 163,95 N com o duplo e com o ponto de Mason-Allen modificado esta foi de 198,45 N. CONCLUSÃO: não existe diferença da resistência no tendão quanto à falha na interface sutura - tendão comparando-se o ponto duplo com o Mason-Allen modificado e os pontos simples e duplo, porém há diferença quando comparados os pontos simples e Mason-Allen modificado.OBJECTIVE: The purpose of this study was to compare the rotator cuff tendon resistance at the interface tendon-suture using three different sorts of stitches (simple, mattress and modified Mason-Allen. METHODS: To do this, 30 rotator cuffs were totally dissected from 15 specimens, which were 45 years old on average. The tests were done using a Kratos® 500/2000 machine and the statistical analyses applied were the Student t-test, ANOVA test, Multiple Bonferroni Comparison, and Pearson's correlation coefficients; all the analyses used a significance level of 5%. RESULTS: No significant difference was observed regarding the age, sample sizes and

  5. Avaliação da microcirculação das bordas do tendão do supra-espinal nas lesões do manguito rotador Microvascular evaluation of the supraspinatus tendon borders in rotator cuff lesions

    Directory of Open Access Journals (Sweden)

    Roberto Yukio Ikemoto

    2007-12-01

    Full Text Available OBJETIVOS: Avaliar a microcirculação das bordas do tendão supra-espinal nas lesões do manguito rotador com a finalidade de determinar a necessidade ou não do desbridamento de suas bordas no momento do seu reparo cirúrgico. MÉTODOS: No período de junho a dezembro de 2004, foram avaliadas amostras recolhidas de 31 pacientes portadores de lesão completa do tendão supra-espinal, submetidos ao tratamento da lesão do manguito rotador por via artroscópica. Apresentavam idade entre 42 e 82 anos (média de 56,6 anos, sendo nove do sexo masculino e 22 do feminino. Durante a realização do procedimento, foram retiradas amostras de tecido da lesão do manguito rotador e enviadas para estudo anatomopatológico com coloração com hematoxilina-eosina. Após esse processo, foi realizada a contagem das fendas vasculares/mm². Utilizaram-se como grupo controle 10 amostras de tendões normais do supra-espinal de cadáveres frescos, submetidos aos mesmos processos anteriores. Os resultados obtidos foram avaliados estatisticamente através da aplicação do teste de Mann-Whitney. RESULTADOS: Entre as amostras, 28 apresentaram tecidos vascularizados e três, ausência de vascularização. O número médio de fendas vasculares/mm² nas amostras de lesões do manguito rotador foi estatisticamente maior que o do grupo controle. CONCLUSÃO: A maioria das bordas das lesões dos tendões do supra-espinal é hipervascularizada.OBJECTIVES: To evaluate microvasculature in the borders of the supraspinatus tendon in rotator cuff lesions in order to determine the need to debrid the borders when surgical repair is performed. METHODS: From June to December 224, samples were evaluated from 31 patients with full lesion of the supraspinatus tendon that had been submitted to arthroscopic rotator cuff lesion treatment. They were between 42 and 82 years of age (mean 56.6 years, nine of them male, and twenty-two female. During the procedure, samples of the rotator cuff

  6. Comparação do ultrassom pulsado e contínuo no reparo tendíneo de ratos Comparison of pulsed and continuous ultrasound on tendon repair in rats

    Directory of Open Access Journals (Sweden)

    Gladson Ricardo Flor Bertolini

    2012-09-01

    Full Text Available No tratamento de lesões tendíneas, o uso do ultrassom surge como possibilidade terapêutica, apesar de lacunas sobre seus efeitos clínicos. O objetivo foi avaliar dois protocolos de ultrassom terapêutico sobre dor e edema após trauma tendíneo. Vinte e um ratos Wistar foram submetidos a trauma no tendão calcâneo e divididos em três grupos: sham (GS; ultrassom contínuo (GUC; e ultrassom pulsado (GUP. O trauma ocorreu sobre a face lateral do tendão calcâneo direito, com energia de 0,40 J. A dor foi avaliada pelo teste de incapacidade funcional e o edema, pelo diâmetro laterolateral. Foram realizadas avaliações previamente à lesão; após 1 hora da indução da lesão; após o 1º tratamento; 2, 8 e 24 horas após lesão; e após o 5º dia. O tratamento ocorreu em 5 dias, com transdutor de 1 MHz, durante 3 minutos, sobre o local do trauma, com dose de 0,4 W/cm² SATA. Os resultados da incapacidade funcional para GS mostraram aumento da nocicepção. Para GUC houve aumento ao comparar a avaliação 1 (AV1 com as avaliações 2 (AV2, 3 (AV3 e 4 (AV4; ao comparar AV2 com as avaliações 5 (AV5 e 6 (AV6 houve diminuição de valores. Para GUP houve aumento ao comparar AV1 com AV2 e AV3, mas ao comparar AV2 com as seguintes, houve diminuição significativa a partir de AV4. Para o edema, os grupos tratados produziram aumento inicial, com redução nas últimas avaliações. O ultrassom terapêutico produziu diminuição de dor e edema, mais precocemente para a forma pulsada.In tendon injuries treatment, the use of ultrasound appears as a therapeutic option, despite the lack of their clinical effects. The aim was to evaluate two therapeutic ultrasound protocols, continuous or pulsed, on the pain and swelling after tendinous trauma. Twenty-one Wistar rats were subjected to traumatic injury in the tendon and divided in three groups: sham (GS, continuous ultrasound (GUC, and pulsed ultrasound (GUP. The injury occurred on right Achilles tendon

  7. Lesão do ligamento cruzado anterior: tratamento e reabilitação. Perspectivas e tendências atuais Anterior cruciate ligament injury: treatment and rehabilitation. Current perspectives and trends

    Directory of Open Access Journals (Sweden)

    Gustavo Gonçalves Arliani

    2012-04-01

    Full Text Available OBJETIVO: O objetivo deste estudo é avaliar as condutas e procedimentos realizados pelos cirurgiões de joelho do Brasil no tratamento e reabilitação das lesões do ligamento cruzado anterior. MÉTODOS: Um questionário de 21 questões fechadas foi elaborado abordando tópicos relacionados ao tratamento e reabilitação após reconstrução do LCA. O questionário foi aplicado a cirurgiões brasileiros de joelho durante os três dias do 42º Congresso Brasileiro de Ortopedia e Traumatologia do ano de 2010. RESULTADOS: No total, 226 cirurgiões preencheram completamente o questionário e fizeram parte da amostra analisada. A maior parte destes era proveniente da região Sudeste do País. Os tipos de enxerto mais utilizados foram os tendões flexores e o terço central do tendão patelar ipsilateral à lesão, utilizados por 82,3% e 53,5% da amostra, respectivamente. A técnica de reconstrução com banda única transtibial é a preferida, sendo realizada por 66,4% dos participantes. O período de uma a quatro semanas entre a lesão e a realização do procedimento cirúrgico foi o considerado ideal pela maioria dos participantes (52,65%. Queixa de falseio/instabilidade do paciente e presença da manobra de pivot-shift positiva no exame físico foram os fatores considerados mais determinantes na decisão de operar o paciente. Já a satisfação do paciente e a ausência de queixas de instabilidade no pós-operatório foram os critérios julgados mais importantes para considerar a cirurgia um sucesso. CONCLUSÕES: Existem claras tendências em evolução no tratamento e reabilitação do LCA no Brasil. No entanto, mais estudos prospectivos controlados são necessários para avaliar o benefício clínico e científico destas tendências.OBJECTIVE: The aim of this study was to evaluate the procedures used by knee surgeons in Brazil for treating and rehabilitating anterior cruciate ligament injuries. METHODS: A questionnaire consisting of 21 closed

  8. Escalas temporais e tendências observadas nas temperaturas m áximas no Estado do Ceará Timescales and observed trends in the highest temperatures in the state of Ceará

    OpenAIRE

    Costa, Iuri Moreira; UFC Campus Cariri; Mateus, Antonio Edgar; UFC Campus Cariri; Da Silva, Djane Fonseca; UFC Campus Cariri

    2014-01-01

    Pretendeu-se por meio das análises de ondeletas, identificar quais as possíveiscausas para a variabilidade na temperatura máxima do Ceará e com auxílio do teste de Mann-Kendall, verificou-se se há tendências de aumento ou diminuição dessa variável. Foram usados dados de temperatura máxima do INMET para o período de 1973-2010. Verificou-se que as regiões do estado do Ceará sofrem influencia das variações das escalas sazonais, interanuais e decadais sob suas temperaturas. As escalas sazonal, li...

  9. Tendências na variabilidade climática sazonal e anual das temperaturas máxima e mínima do ar no Estado do Paraná

    OpenAIRE

    Minuzzi,Rosandro Boligon; Caramori,Paulo Henrique; Borrozino,Edmirson

    2011-01-01

    O presente trabalho teve por objetivo analisar a variabilidade sazonal e anual das temperaturas máxima e mínima do ar no Estado do Paraná. A Análise de Regressão e o teste de Kendall foram utilizados para testar a tendência das médias de temperatura máxima e mínima, do número de dias com registros de temperatura inferior a 3 °C, dos eventos extremos e valores absolutos diários da temperatura máxima e mínima nas escalas sazonal (verão, outono, inverno e primavera) e anual. Os pontos de descont...

  10. Tendências das mudanças da proteção social no Brasil e no Uruguai: a centralidade das redes mínimas na América Latina

    Directory of Open Access Journals (Sweden)

    Alejandra Pastorini

    2014-06-01

    Full Text Available http://dx.doi.org/10.1590/S1414-49802014000100006 O objetivo deste trabalho é compreender as alterações na lógica que orienta o trato das manifestações da questão social na atualidade, tomando como referência a realidade do Brasil e do Uruguai. Inicia-se pela análise das mudanças contemporâneas nas sociedades capitalistas, prestando especial atenção nas alterações dos princípios que estruturam a proteção social. Dessa forma, identifica-se algumas tendências das reformas nas políticas sociais nos governos progressistas que se consolidam na virada do século.

  11. Desequilíbrios musculares entre flexores dorsais e plantares do tornozelo após tratamento conservador e acelerado da ruptura do tendão calcâneo

    OpenAIRE

    Mayer,Alexandre; Frasson,Viviane Bortoluzzi; Ott,Rafael; Fortuna,Rafael de Oliveira; Vaz,Marco Aurélio

    2010-01-01

    A ruptura do tendão calcâneo (TC) reduz a sobrecarga mecânica dos flexores plantares (FP) do tornozelo. Essa alteração muda o equilíbrio natural entre os FP e flexores dorsais (FD) do tornozelo. O objetivo do estudo foi avaliar as razões isocinéticas concêntricas convencionais de torque de pacientes submetidos a tratamento cirúrgico de ruptura aguda do TC após dois protocolos diferentes de reabilitação. Após procedimento cirúrgico para reconstrução do TC, a amostra foi dividida de forma inten...

  12. Central Clearing of OTC Derivatives

    DEFF Research Database (Denmark)

    Cont, Rama; Kokholm, Thomas

    2014-01-01

    netting agreements. When a CCP exists for interest rate derivatives, adding a CCP for credit derivatives is shown to decrease overall exposures. These findings are shown to be robust to the statistical assumptions of the model as well as the choice of risk measure used to quantify exposures....

  13. Tendências na variabilidade climática sazonal e anual das temperaturas máxima e mínima do ar no Estado do Paraná

    Directory of Open Access Journals (Sweden)

    Rosandro Boligon Minuzzi

    2011-01-01

    Full Text Available O presente trabalho teve por objetivo analisar a variabilidade sazonal e anual das temperaturas máxima e mínima do ar no Estado do Paraná. A Análise de Regressão e o teste de Kendall foram utilizados para testar a tendência das médias de temperatura máxima e mínima, do número de dias com registros de temperatura inferior a 3 °C, dos eventos extremos e valores absolutos diários da temperatura máxima e mínima nas escalas sazonal (verão, outono, inverno e primavera e anual. Os pontos de descontinuidade obtidos pelo Teste de Homogeneidade Normal Padrão mostram resultados mais expressivos para a temperatura máxima anual e no outono. Para esta variável meteorológica os pontos foram obtidos predominantemente no início da década de 2000. Na temperatura máxima anual e, principalmente na temperatura mínima, em todas as escalas de tempo, houve tendência de aumento. Esse aumento relativamente maior da temperatura mínima sugere uma diminuição na amplitude térmica no Paraná. Os valores dos extremos diários da temperatura mínima estão sendo maiores, porém, menos freqüentes. Por outro lado, as temperaturas máximas têm sido mais intensas e freqüentes, especialmente na primavera.

  14. Comparação entre as tendências e estratégias da indústria automotiva no Brasil e na Europa Trends and strategies in the automotive industry: a comparative study of Brazilian and European markets

    Directory of Open Access Journals (Sweden)

    Luiz Felipe Scavarda

    2005-12-01

    Full Text Available A indústria automotiva está passando por transformações que vêm provocando a diversificação e segmentação do mercado, a redução do ciclo de vida de modelos de veículos e a oferta de variedades de atributos desses modelos para os clientes. Este artigo tem por objetivos analisar essas tendências e avaliar as principais estratégias desenvolvidas e implementadas pelas montadoras de veículos nos mercados brasileiro e europeu, para fazer face a estas tendências. Os resultados obtidos no Brasil pelos autores deste artigo foram analisados tendo como base a metodologia científica adotada em uma pesquisa similar desenvolvida na Europa. Os resultados mostram como as estratégias de plataformas, de configuração tardia e de pacotes de opcionais estão sendo implementadas pelas montadoras, permitindo uma comparação entre os dois mercados examinados.The automotive industry is undergoing transformations that have led to the segmentation and diversification of its market, reductions in the life cycle of vehicle models, and the offer of a variety of features of these models to consumers. Within this context, this paper analyzes these trends and evaluates the key strategies developed and implemented by Brazilian and European automakers in face of these trends. Our findings, which are analyzed using the same methodology adopted in a similar survey conducted in Europe, indicate how platform, late configuration and option bundling strategies have been implemented by automakers, allowing for a comparison of the two markets in question.

  15. O lúdico e o ensino de Geociências no Brasil: principais tendências das publicações na área de Ciências da Natureza

    Directory of Open Access Journals (Sweden)

    Danilo Missias Teixeira

    2018-01-01

    Full Text Available As atividades lúdicas são metodologias de ensino que vêm conquistando espaço no Ensino de Ciências; proporcionam um estudo dos conceitos de forma mais dinâmica e prazerosa. Todavia, quando se trata dos conceitos de Geociências as dificuldades apresentadas pelos professores de Ciências Exatas e Biológicas acabam por fazer com que estes profissionais não elaborem propostas vinculadas a tais conceitos. O objetivo deste trabalho é, portanto, identificar na literatura científica do Ensino de Ciências as principais tendências de pesquisas com características lúdicas que possuam como foco os conceitos de Geociências. Para isso, foi realizada uma busca em: (a banco de Teses e Dissertações da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES, e (b periódicos vinculados ao Ensino de Ciências. Como resultado, foi possível observar que as publicações lúdicas no Ensino de Ciências apresentam as seguintes tendências: (1 A maior parte das publicações tem origem na região Sudeste, principalmente nos estados de Rio de Janeiro e São Paulo; (2 O número de publicações é crescente a partir do ano de 2014, com ponto forte no ano 2016; (3 a maior área de conhecimento a apresentar trabalhos é Química, seguida de Biologia; (4 as publicações são, em sua maior parte, experiências realizadas no Ensino Médio, e (5 a modalidade lúdica preferencial é “Jogo Didático”.

  16. Tendência genética para a produção de leite e de gordura em rebanhos da raça Holandesa no Estado de Minas Gerais

    Directory of Open Access Journals (Sweden)

    Durães Marcus Cordeiro

    2001-01-01

    Full Text Available O objetivo deste trabalho foi estimar as tendências genéticas para a produção de leite e gordura nos rebanhos da raça Holandesa do Estado de Minas Gerais. As análises estatísticas foram realizadas por intermédio da metodologia dos modelos mistos, usando-se máxima verossimilhança restrita e modelo animal. Os efeitos fixos considerados no modelo foram: rebanho-ano-estação de parto e os efeitos linear e quadrático da idade da vaca ao parto. Os efeitos aleatórios foram animal e erro. A tendência genética foi calculada pela regressão do valor genético sobre o ano de nascimento da vaca; nesta análise, foram usados 18.482 registros de produção de leite e gordura de vacas de primeira cria, nascidas de 1986 a 1996. As estimativas de ganho genético para produção de leite e gordura foram 18,4 e 0,6 kg, respectivamente. A média de produção de leite e gordura aumentou anualmente, variando de 5083 ± 50 a 6876 ± 51 kg, e de 172,6 ± 1,7 a 228,5 ± 1,7 kg, respectivamente. Os valores genéticos estimados foram negativos em 1986 e 1987 e positivos após este período, com aumento acentuado nos últimos anos, indicando que os produtores de leite de Minas Gerais vêm adotando critérios para aumentar a capacidade de produção de seus rebanhos.

  17. Tachometers Derived From a Brushless DC Motor

    Science.gov (United States)

    Howard, David E.; Smith, Dennis A.

    2007-01-01

    The upper part of the figure illustrates the major functional blocks of a direction-sensitive analog tachometer circuit based on the use of an unexcited two-phase brushless dc motor as a rotation transducer. The primary advantages of this circuit over many older tachometer circuits include the following: Its output inherently varies linearly with the rate of rotation of the shaft. Unlike some tachometer circuits that rely on differentiation of voltages with respect to time, this circuit relies on integration, which results in signals that are less noisy. There is no need for an additional shaft-angle sensor, nor is there any need to supply electrical excitation to a shaft-angle sensor. There is no need for mechanical brushes (which tend to act as sources of electrical noise). The underlying concept and electrical design are relatively simple. This circuit processes the back-electromagnetic force (back-emf) outputs of the two motor phases into a voltage directly proportional to the instantaneous rate (sign magnitude) of rotation of the shaft. The processing in this circuit effects a straightforward combination of mathematical operations leading to a final operation based on the well-known trigonometric identity (sin x)2 + (cos x)2 = 1 for any value of x. The principle of operation of this circuit is closely related to that of the tachometer circuit described in Tachometer Derived From Brushless Shaft-Angle Resolver (MFS-28845), NASA Tech Briefs, Vol. 19, No. 3 (March 1995), page 39. However, the present circuit is simpler in some respects because there is no need for sinusoidal excitation of shaftangle- resolver windings.

  18. Derivation of Sky-View Factors from LIDAR Data

    Science.gov (United States)

    Kidd, Christopher; Chapman, Lee

    2013-01-01

    The use of Lidar (Light Detection and Ranging), an active light-emitting instrument, is becoming increasingly common for a range of potential applications. Its ability to provide fine resolution spatial and vertical resolution elevation data makes it ideal for a wide range of studies. This paper demonstrates the capability of Lidar data to measure sky view factors (SVF). The Lidar data is used to generate a spatial map of SVFs which are then compared against photographically-derived SVF at selected point locations. At each location three near-surface elevations measurements were taken and compared with collocated Lidar-derived estimated. It was found that there was generally good agreement between the two methodologies, although with decreasing SVF the Lidar-derived technique tended to overestimate the SVF: this can be attributed in part to the spatial resolution of the Lidar sampling. Nevertheless, airborne Lidar systems can map sky view factors over a large area easily, improving the utility of such data in atmospheric and meteorological models.

  19. Analysis of a Stretched Derivative Aircraft with Open Rotor Propulsion

    Science.gov (United States)

    Berton, Jeffrey J.; Hendricks, Eric S.; Haller, William J.; Guynn, Mark D.

    2015-01-01

    Research into advanced, high-speed civil turboprops received significant attention during the 1970s and 1980s when fuel efficiency was the driving focus of U.S. aeronautical research. But when fuel prices declined sharply there was no longer sufficient motivation to continue maturing the technology. Recent volatility in fuel prices and increasing concern for aviation's environmental impact, however, have renewed interest in unducted, open rotor propulsion and revived research by NASA and a number of engine manufacturers. Recently, NASA and General Electric have teamed to conduct several investigations into the performance and noise of an advanced, single-aisle transport with open rotor propulsion. The results of these initial studies indicate open rotor engines have the potential to provide significant reduction in fuel consumption compared to aircraft using turbofan engines with equivalent core technology. In addition, noise analysis of the concept indicates that an open rotor aircraft in the single-aisle transport class would be able to meet current noise regulations with margin. The behavior of derivative open rotor transports is of interest. Heavier, "stretched" derivative aircraft tend to be noisier than their lighter relatives. Of particular importance to the business case for the concept is how the noise margin changes relative to regulatory limits within a family of similar open rotor aircraft. The subject of this report is a performance and noise assessment of a notional, heavier, stretched derivative airplane equipped with throttle-push variants of NASA's initial open rotor engine design.

  20. A diferença étnico-racial em livros brasileiros para crianças: Análise de três tendências contemporâneas

    Directory of Open Access Journals (Sweden)

    Edgar Roberto Kirchof

    2015-08-01

    Full Text Available In the current scenario of Brazilian children’s literature production, there is a significant increase in the number of books that address ethnic and racial issues, which may be seen as a likely consequence of the laws establishing the teaching of Afro-Brazilian, African and Indian history and culture at schools. The aim of this paper is to analyze how Brazilian contemporary children's literature has been approaching ethnic-racial issues. Based on the analysis of 22 recent works published in Brazil, three main approaches to ethnic issues were detected. According to the first one, ethnic difference triggers racism on the part of some characters and this works as the narrative conflict. Throughout the plot, the conflict is always overcome, what suggests a clear lesson of goodwill and/or of acceptance of the different. In a second approach, black children characters are placed into narrative plots whose main conflicts do not arise directly from ethnic-racial issues. In these books, blackness is not characterized as an element that triggers conflicts, but it is part of a broader aesthetic intention. The third approach proposes a rather celebratory manner of representing diversity and difference. In these works, the specific issue of ethnic difference is approached together with other issues related to diversity and differences. No cenário atual de produção de obras literárias para crianças no Brasil, há um crescimento significativo de livros que abordam questões étnico-raciais nos últimos anos, o que pode ser visto como uma provável consequência das leis que instituem o ensino da cultura e da história afro-brasileiras, africanas e indígenas nas escolas. Diante desse contexto, o objetivo do presente artigo é analisar como a literatura infantil contemporânea brasileira tem abordado questões étnico-raciais. A partir de 22 obras recentes publicadas no Brasil, foi possível verificar a existência de três principais tendências. Na

  1. Chemistry of aliphatic sulfurpentafluoride derivatives

    International Nuclear Information System (INIS)

    Bissell, E.R.

    1975-01-01

    This report summarizes the literature through 1974 on aliphatic sulfurpentafluoride compounds. Methods of preparation and methods of transforming one pentafluorothio compound into another are briefly discussed. The physical properties of all known derivatives are tabulated

  2. Higher derivatives in gauge transformations

    International Nuclear Information System (INIS)

    Gogilidze, S.A.; Sanadze, V.V.; Tkebuchava, F.G.

    1992-01-01

    The mechanism of appearance of highher derivatives of coordinates in the symmetry transformation law of the second Noether's theorem is established. It is shown that the corresponding transformations are canonical in the extended phase space. 15 refs

  3. Tendências de aplicações da otimização por colônia de formigas na progamação de JOB-SHOPS

    Directory of Open Access Journals (Sweden)

    Felipe Fonseca Tavares de Freitas

    2009-11-01

    Full Text Available A programação da produção revela-se como uma atividade que, se bem planejada, otimizada e controlada, gera grandes vantagens competitivas e duradouras para a empresa. Um dos problemas mais complexos de programação da produção ocorre em sistemas do tipo job-shop – os quais envolvem otimização combinatória, cuja resolução em tempo computacional aceitável é quase sempre improvável (NP-hard. Neste contexto, vários métodos de otimização têm sido pesquisados e desenvolvidos nas últimas décadas, almejando-se planos de produção cada vez melhores, sob tempos de execução computacional gradativamente menores e viáveis para a indústria. Em especial, destaca-se o uso das técnicas de inteligência coletiva que, mimetizando fenômenos biológicos e sociais da natureza, vêm obtendo bons resultados quando aplicadas a problemas do tipo job shop scheduling (JSS. Revisando-se a teoria referente à meta-heurística de Otimização por Colônia de Formigas (ou Ant Colony Optimization - ACO e suas aplicações em problemas de JSS, este artigo identifica e explica as principais tendências de pesquisa nessa área, tanto a nível mundial quanto nacional. Como resultados deste estudo, pode-se vislumbrar a hibridização entre ACO e outros algoritmos de otimização e o tratamento de cenários de JSS cada vez mais complexos como as tendências mais relevantes dos trabalhos envolvendo ACO e problemas de programação de job-shops.

  4. A tendência cambiante da relação entre escolaridade e risco de obesidade no Brasil (1975-1997 The changing relationship between education and risk of obesity in Brazil (1975-1997

    Directory of Open Access Journals (Sweden)

    Carlos Augusto Monteiro

    2003-01-01

    Full Text Available A partir de três inquéritos comparáveis realizados no último quarto do século vinte nas duas mais populosas regiões brasileiras, evidenciou-se uma mudança substancial na tendência secular da obesidade segundo níveis de escolaridade da população. Enquanto no primeiro período (1975-1989, o risco de obesidade foi ascendente em todos os níveis de escolaridade, tendendo a ascensão a ser máxima para homens e mulheres com maior escolaridade; no segundo período (1989-1997, o aumento da obesidade foi máximo para indivíduos sem escolaridade, registrando-se estabilidade ou mesmo diminuição da enfermidade nos estratos femininos de média ou alta escolaridade. Como resultado da tendência recente, diminui a relação positiva entre escolaridade e risco de obesidade em homens e acentua-se a relação inversa que já vinha se observando na população feminina. As principais implicações dos achados deste estudo são apreciadas do ponto de vista da Saúde Pública.Based on three comparable surveys conducted in the last quarter of the 20th century in the most heavily populated areas of Brazil, a substantial change was observed in the secular trend towards obesity based on levels of schooling in the population. While during the first period (1975-1989 there was an increasing risk of obesity for all levels of schooling, with the greatest upward trend for men and women with more schooling, during the second period (1989-1997 the increase in obesity was the greatest for individuals with no schooling, along with a stabilization or even decrease in this condition among groups of females with medium or higher education. As a result of the upward trend, the positive relationship decreased between schooling and risk of obesity in men, and the inverse relationship already observed in the female population was further increased. The main potential implications of these findings are for public health.

  5. Reforma do Estado e reforma de sistemas de saúde: experiências internacionais e tendências de mudança Reform of the State and reform of health systems: international experiences and trends for changes

    Directory of Open Access Journals (Sweden)

    Célia Maria de Almeida

    1999-01-01

    Full Text Available Este texto discute a agenda de reforma do Estado, avaliando seus eixos centrais e dificuldades de implementação; identifica as traduções que adquire nos modelos que vêm sendo implementados na área de saúde e analisa as reformas de alguns países (EUA, Reino Unido e Colômbia. Aponta ainda as perspectivas que se desenham como tendências nas propostas de reforma setorial no Brasil, vis a vis a experiência internacional, onde a idéia de separação de funções de financiamento e execução tem prosperado, enquanto a de introdução de mecanismos competitivos na alocação de recursos financeiros tem sido objeto de várias críticas. Além disso, discute esses mecanismos em termos de eficiência e eficácia e da capacidade regulatória do Estado. Reflete sobre o quanto os países latino-americanos têm sido mais radicais nos seus processos de reforma, mesmo partindo de condições muito precárias e estando submetidos a constrangimentos financeiros e importante subfinanciamento setorial. Aponta como tendência, na América Latina, possibilidades de desmonte dos sistemas anteriores, sem garantia de melhoras substantivas na cobertura e na eqüidade, seja pelo radicalismo do processo, seja pelo alto grau de experimentalismo com que as reformas estão sendo implementadas.This text discusses the agenda for reform of the State, assessing the central themes and the difficulties facing implementation; it identifies the forms it takes in models being implemented in the area of health care and analyzes some countries' reforms (USA, United Kingdom and Colombia. It also points to approaches emerging as trends in proposals for sector reform in Brazil, vis a vis the international experience, where the idea of split between financing and provision functions has been flourished, and that introducing competition mechanisms into resource allocation has been hardly criticized. Although beginning from far more precarious conditions, Latin American reforms

  6. Relevância da ultra-sonografia dos tendões flexores em cavalos Puro Sangue de corrida na adaptação ao treinamento Significance of flexor tendon ultrasonography in training thoroughbred horses

    Directory of Open Access Journals (Sweden)

    Carolina Roxana Greig

    2005-08-01

    Full Text Available Vinte e quatro potros Puro Sangue de Corrida (PSC, com dois anos de idade foram avaliados ultra-sonograficamente, durante o período final da doma e início de treinamento, através da imagem transversal dos tendões flexor digital superficial (TFDS e profundo (TFDP. As avaliações foram realizadas com intervalos de 15 dias. A área transversal (AT, a textura dos ecos e a ecogenicidade dos tendões foram avaliadas nas sete zonas da região metacarpiana através de um programa de mensuração de imagens do próprio aparelho de ultra-sonografia. Durante a doma e treinamento, houve diminuição da AT na zona IA e IIIA (PThe cross-sectional area (CSA of the superficial digital flexor tendon (SDFT and deep digital flexor tendon (DDFT of twenty four thoroughbreds was ultrasonographically evaluated before and during their initial training to determine the effect of exercise on the tendon CSA, texture and echogenicity to characterize the response to training. Ultrasonographic transverse images of the left forelimb were obtained every fifteen days. The SDFT CSA of zones IA and IIIA showed a decrease (P<0.05, f=0.010 e f=0.023 res. during the breaking and training period and an increase (P< 0.05 of zone IIIC (f=0.039. Evaluating just the training period, SDFT CSA results of zones IA, IIIA and IIIC were similar. The DDFT showed no variation during the breaking phase but when the training phase was evaluated there was a decrease (P<0.05 in zones IA (f=0.006 and IIIA (f=0.006. Evaluating both breaking and training periods the DDFT showed a decrease (P<0.05 in zones IA (f=0.027, IIIA (f=0.0001 and IIIB (f=0.0031. Fiber texture and tendon echogenicity showed no significant difference between breaking and last reading during training. This study provides evidence of variation of adaptation among the ultrasonographic zones of both SDFT and DDFT to exercise during training of thoroughbred horses. Ultra-sonography is not the most indicated method to evaluate the

  7. Push-outs of derivations

    Indian Academy of Sciences (India)

    extension as a limit of operators b ↦→ D(ba) − b.D(a), a ∈ A in an appropriate operator topology, the main point in the proof being to show that the limit map is in fact a derivation. In this paper we make clear which part of this approach is analytic and which algebraic by presenting an algebraic scheme that gives derivations ...

  8. Elementary derivation of Kepler's laws

    International Nuclear Information System (INIS)

    Vogt, E.

    1995-02-01

    A simple derivation of all three so-called Kepler Laws is presented in which the orbits, bound and unbound, follow directly and immediately from conservation of energy and angular momentum. The intent is to make this crowning achievement of Newtonian Mechanics easily accessible to students in introductory physics courses. The method is also extended to simplify the derivation of the Rutherford Scattering Law. (author). 4 refs., 3 figs

  9. Derivatives Trading and Negative Voting

    OpenAIRE

    Spamann, Holger

    2012-01-01

    This paper exposits a model of parallel trading of corporate securities (shares, bonds) and derivatives in which a large trader can sometimes profitably acquire securities with their corporate control rights for the sole purpose of reducing the corporations value and gaining on a net short position created through off-setting derivatives. At other times, the large trader profitably takes a net long position. The large trader requires no private information beyond its own trades. The problem i...

  10. Quinazoline derivatives: synthesis and bioactivities

    OpenAIRE

    Wang, Dan; Gao, Feng

    2013-01-01

    Owing to the significant biological activities, quinazoline derivatives have drawn more and more attention in the synthesis and bioactivities research. This review summarizes the recent advances in the synthesis and biological activities investigations of quinazoline derivatives. According to the main method the authors adopted in their research design, those synthetic methods were divided into five main classifications, including Aza-reaction, Microwave-assisted reaction, Metal-mediated reac...

  11. Tendência temporal da mortalidade por doenças infecciosas intestinais em crianças menores de cinco anos de idade, no estado de São Paulo, 2000-2012

    Directory of Open Access Journals (Sweden)

    Renata Soares Martins

    Full Text Available Resumo OBJETIVO: analisar a tendência temporal da mortalidade por doenças infecciosas intestinais (DII em crianças menores de cinco anos de idade no estado de São Paulo e suas Redes Regionais de Atenção à Saúde (RRAS, no período 2000-2012. MÉTODOS: estudo de série temporal sobre os óbitos com causa básica, antecedente ou contribuinte de morte por DII, obtidos a partir do Sistema de Informações sobre Mortalidade (SIM. RESULTADOS: ocorreram 2.886 óbitos por DII no estado; a taxa de mortalidade por DII apresentou diminuição de 10,5% ao ano (intervalo de confiança de 95% 4,8; 15,8%; em 13 das 17 RRAS ocorreu diminuição significativa da taxa de mortalidade, com decréscimo anual variável entre 16,6 e 8,3% ao ano. CONCLUSÃO: a taxa de mortalidade por DII apresentou decréscimo significativo na maioria das RRAS, com diferentes velocidades, possível reflexo das desigualdades das condições socioeconômicas e de organização das redes de atenção à saúde.

  12. Paradigmas e tendências do ensino universitário: a metodologia da pesquisa-ação como estratégia de formação docente

    Directory of Open Access Journals (Sweden)

    Erica Toledo de Mendonça

    2015-06-01

    Full Text Available O objetivo do trabalho foi discutir sobre os paradigmas e as tendências do ensino universitário na atualidade, apontando estratégias de formação docente. Utilizou-se como método a pesquisa-ação; os dados foram coletados mediante as técnicas do Panorama Sobe e Desce, Wordle e Diários de Classe, durante a realização de capacitações docentes para exercício de tutoria em disciplina semipresencial. Os depoimentos dos participantes apontaram para uma insatisfação no uso do modelo tradicional de ensino; a importância de o professor estar aberto ao novo; e, ainda, que a utilização de processos inovadores de ensinagem foi considerada importante estratégia de mudança de paradigma educacional. O processo de capacitação de docentes universitários mostrou-se eficaz no que tange à conscientização destes indivíduos quanto à importância de se inserir o ensino na agenda das prioridades da universidade.

  13. Produção científica em Ciências Biológicas da UFRGS: tendências temáticas no período 2000-2011

    Directory of Open Access Journals (Sweden)

    Dirce Maria Santin

    Full Text Available O estudo apresenta as principais temáticas da pesquisa em Ciências Biológicas da Universidade Federal do Rio Grande do Sul (UFRGS com base na análise da produção científica publicada no período de 2000 a 2011 e indexada na Web of Science (WoS. Destaca as temáticas evidenciadas nas categorias de assuntos e nas palavras-chave dos autores de 5.168 artigos que integram a amostra. A metodologia utilizada é a bibliometria e os resultados apontam para Neurociências, Bioquímica & Biologia Molecular, Farmacologia & Farmácia e Genética & Hereditariedade como as áreas mais produtivas, enquanto Estresse oxidativo; Doença; Memória; Receptor; Hipocampo; Rato; e Resistência se destacam como os principais temas de pesquisa. A produção científica apresentou crescimento significativo no período e as tendências temáticas da área constituem objetos de estudo das disciplinas mais produtivas, embora outros temas se mostrem igualmente significativos. Avalia-se que a UFRGS acompanha o desenvolvimento das Ciências Biológicas no contexto nacional e internacional, realizando pesquisas de amplo interesse na atualidade.

  14. Planejamento e gestão em saúde: histórico e tendências com base numa visão comunicativa Planning and management in health: historical and tendencies based on a communicative view

    Directory of Open Access Journals (Sweden)

    Francisco Javier Uribe Rivera

    2010-08-01

    Full Text Available Este artigo tem por objetivos apresentar uma visão condensada das principais tendências no Brasil, estabelecer uma taxonomia geral dos modelos de planejamento e gestão em saúde, tendo como base o cenário internacional e fundamentar a proposta de um planejamento comunicativo. Em um contexto de democratização, argumenta a favor de uma concepção pluralista e conclui que as diversas correntes, embora com diferentes perspectivas e encaminhamentos teórico-metodológicos, dialogam num processo de troca mútua e de aprendizagem.This article aims to present a condensed overview of major trends in Brazil, establish a general taxonomy of models of health management and planning, based on the international scene and support the proposal for a communicative planning. In a context of democratization, argues for a pluralistic conception and concludes that the various currents, albeit with different perspectives and referrals theoretical and methodological dialogue in a process of mutual exchange and learning.

  15. Tendències en el disseny metodològic de recerca sobre l’avaluació de competències a l’educació superior

    Directory of Open Access Journals (Sweden)

    Karina Angélica Villegas Sandoval

    2017-01-01

    Full Text Available L’article té com a finalitat descriure i analitzar les metodologies d'investigació utilitzades per estudis recents que aborden el tema de l’avaluació per competències a l’educació superior i la formació docent, per tal de detectar les tendències en el disseny metodològic i orientar futurs projectes d'investigació sobre aquest tema. El mètode de treball que s'ha seguit per dur a terme aquest estudi és l’anàlisi de contingut de 22 documents trobats a Dialnet. Els resultats mostren que les investigacions que tracten el tema assenyalat han anat en augment en els últims tretze anys, i es destaca el canvi de metodologia utilitzada, amb dissenys majoritàriament descriptius i avaluatius. Al seu torn, però, crida l'atenció que un gran nombre d'estudis no expliquen ni el mètode ni el disseny d'investigació que han aplicat. Es conclou que és important que les investigacions presentin un apartat que al·ludeixi al disseny metodològic a fi d’afavorir la comprensió del lector dels processos d'indagació que s'han dut a terme.

  16. De cidades e sociedades: estética, contextos e as tendências na representação urbana e da periferia em videoclipes da América Latina

    Directory of Open Access Journals (Sweden)

    Victória Costa

    2017-12-01

    Full Text Available Neste ensaio analisamos e discutimos a relação entre a experiência dos indivíduos e ruas, bairros e cidades, especialmente de áreas consideradas de periferia, que são apresentadas/ representadas em videoclipes de intérpretes e grupos latinos a partir dos anos 2000. Por meio da observação e análise de tais obras – e de outras que aqui são apenas citadas – propomos a divisão em cinco categorias: “Pertencimento”; “Cenários”; “Espaço como produto”; “Luta e denúncia” e “Simbiose”, entre pertencimento e cenários. Tais aspectos comunicariam uma possível tendência em videoclipes e os diálogos entre cidades e sociedades na produção audiovisual contemporânea na América Latina.  Palavras-chave: Cidades. Periferia. Videoclipes. Audiovisual. América Latina.

  17. Tendências da mortalidade por câncer nas capitais dos estados do Brasil, 1980-2004 Trends of cancer mortality in Brazilian state capitals, 1980-2004

    Directory of Open Access Journals (Sweden)

    Luiz Augusto Marcondes Fonseca

    2010-01-01

    Full Text Available OBJETIVO: A mortalidade por câncer iniciou declínio nos países desenvolvidos nos anos 90, mas seu comportamento nos países em desenvolvimento é menos conhecido. Estudo anterior abordando a mortalidade por câncer no Brasil mostrou queda na mortalidade pelo conjunto dos cânceres, mas a qualidade dos dados suscitou críticas quanto à validade dos resultados. As informações de mortalidade das capitais dos estados do Brasil são de melhor qualidade que aquelas para o país como um todo, possibilitando análise mais acurada das tendências. MÉTODOS: Os dados de mortalidade e população foram obtidos das bases de dados do Ministério da Saúde e do IBGE. Calcularam-se taxas ajustadas por idade e taxas específicas por idade, para ambos os sexos. Empregou-se regressão linear para avaliar a significância das mudanças de tendência. RESULTADOS: As taxas de mortalidade pelo conjunto dos cânceres declinaram, (-4,6% para os homens e -10,5% para as mulheres. O câncer de estômago mostrou queda de taxas nos dois sexos, assim como o câncer de pulmão entre os homens, enquanto as taxas do câncer de próstata aumentaram. No sexo feminino, “câncer do útero não especificado" apresentou redução e o câncer de pulmão, aumento de taxas. O câncer de mama mostrou-se estável, e o câncer do colo do útero aumentou suas taxas ao final do período. CONCLUSÃO: Conforme já registrado em países desenvolvidos, a mortalidade pelo conjunto dos cânceres nas capitais de estados brasileiros mostrou tendência de queda entre 1980 e 2004, o que se deveu fundamentalmente ao declínio da mortalidade por câncer de estômago.OBJECTIVE: Cancer mortality rates began to decline in developed countries in the 1990s, but their behavior in developing countries is less well-known. An earlier study on cancer mortality in Brazil showed a declining mortality trend for cancer as a whole. however the quality of data results raised some criticism t. The population

  18. Limited Weight Loss or Simply No Weight Gain following Lifestyle-Only Intervention Tends to Redistribute Body Fat, to Decrease Lipid Concentrations, and to Improve Parameters of Insulin Sensitivity in Obese Children

    Directory of Open Access Journals (Sweden)

    Valeri Lenin

    2011-03-01

    Full Text Available Objectives. To investigate whether lifestyle-only intervention in obese children who maintain or lose a modest amount of weight redistributes parameters of body composition and reverses metabolic abnormalities. Study Design. Clinical, anthropometric, and metabolic parameters were assessed in 111 overweight or obese children (CA of 11.3 ± 2.8 years; 63 females and 48 males, during 8 months of lifestyle intervention. Patients maintained or lost weight (1–5% (group A; n: 72 or gained weight (group B. Results. Group A patients presented with a decrease in systolic blood pressure (SBP and diastolic blood pressure (DBP ( and , resp., BMI (, z-score BMI (, waist circumference (, fat mass (, LDL-C (, Tg/HDL-C ratio (, fasting and postprandial insulin (, and HOMA (, while HDL-C ( and QUICKI increased (. Conversely, group B patients had an increase in BMI (, waist circumference (, SBP (, and in QUICKI (, while fat mass (, fasting insulin (, and HOMA ( decreased. Lean mass, DBP, lipid concentrations, fasting and postprandial glucose, postprandial insulin, and ultrasensitive C-reactive protein (CRP remained stable. Conclusions. Obese children who maintain or lose a modest amount of weight following lifestyle-only intervention tend to redistribute their body fat, decrease blood pressure and lipid levels, and to improve parameters of insulin sensitivity.

  19. Reparação do ligamento cruzado cranial de cães por tendão homólogo conservado em glicerina e associado a fio de náilon

    Directory of Open Access Journals (Sweden)

    Oliveira Simone Tostes de

    2003-01-01

    Full Text Available A ruptura do ligamento cruzado cranial (LCC é uma das patologias de maior prevalência no joelho de cães e sua correção é um problema atual. Após a ruptura experimental do LCC, em cães, implantou-se o tendão do músculo extensor longo dos dedos, homólogo, conservado em glicerina a 98%, associado ao fio de mononáilon, utilizando-se técnica intra-articular. Foram utilizados 18 cães com peso médio de 16,5kg, adultos, separados em três grupos (A, B e C e avaliados por 45, 80 e 120 dias de pós-operatório, respectivamente. Foi realizada avaliação clínica, radiográfica, macroscópica e histológica. A técnica demonstrou-se eficiente para o retorno funcional do membro promovendo estabilidade articular, apesar de o implante biológico ter sido reabsorvido na maioria dos animais, e do fio de náilon ter perdido sua tensão inicial.

  20. Trends in indices for extremes in daily air temperature over Utah, USA Tendências de indices de extremos para temperatura do ar diária sobre Utah, EUA

    Directory of Open Access Journals (Sweden)

    Carlos Antonio Costa dos Santos

    2011-03-01

    Full Text Available The main objective of this study was to obtain analysis of the trends in eleven annual extreme indices of temperature for Utah, United State of America (USA. The analyses have been obtained for 28 meteorological stations, in general, for the period of 1930 to 2006, characterizing a long-term period and with high quality data. The software used to process the data was the RClimdex 1.0. The analysis has identified that the temperature increased in Utah during the last century, evidencing the importance of the ongoing research on climate change in many parts of the world.O principal objetivo desse estudo foi analisar as tendências de onze indices de extremos climáticos baseados em dados diários de temperatura do ar, obtidos a partir de 28 estações meteorológicas localizadas em Utah, Estados Unidos da America (EUA. Em geral, os dados foram coletados entre 1930 e 2006, apresentando coerente resolução temporal e espacial. O software utilizado no processamento dos dados foi o RClimdex 1.0. As análises dos índices extremos mostraram que a temperatura aumentou em Utah durante o último século, evidenciando a importância das pesquisas sobre mudanças climáticas em diferentes partes do mundo.

  1. Efeitos do laser de baixa potência sobre a dor e edema no trauma tendíneo de ratos Effects of the low level laser over pain and edema in tendon trauma of rats

    Directory of Open Access Journals (Sweden)

    Gladson Ricardo Flor Bertolini

    2008-08-01

    Full Text Available A dor e o edema são sinais, entre outros, que ocorrem durante a fase inflamatória no processo de cura de tendões lesados. A terapia antiinflamatória farmacológica recebe algumas críticas, com relação a seus efeitos deletérios para o reparo. Dessa forma, ganha corpo o uso de recursos físicos para o controle do processo. O objetivo do presente estudo foi avaliar o uso do laser de baixa potência sobre a dor e edema em tendão calcâneo de ratos submetidos a trauma experimental. Foram utilizados 28 ratos Wistar, divididos em quatro grupos: GC - submetido à lesão traumática e ao tratamento placebo; G2 - submetido à lesão e irradiado com laser 2J/cm²; G4 - submetido à lesão e irradiado com 4J/cm²; G8 - submetido à lesão e irradiado com 8J/cm². A lesão foi realizada com a queda de um peso sobre a face lateral do tendão calcâneo direito de cada animal, com energia de aproximadamente 0,40J. A dor foi avaliada pelo tempo de elevação da pata (TEP do animal caminhando durante um minuto, sobre um cilindro metálico com 30cm de diâmetro em 3rpm; a avaliação do edema ocorreu através de paquimetria; os momentos de avaliação foram: pré-lesão, pós-lesão, pós-tratamento, duas horas, oito horas, 24 horas e 5º dia de lesão. O tratamento com laser 670nm ocorreu de forma pontual e diária. Os resultados mostraram aumentos do TEP e formação de edema em todos os grupos após a lesão; para os grupos tratados houve redução da dor e do edema, fato observado no grupo controle apenas com relação à diminuição de edema no 5º dia de placebo. Conclui-se que o tratamento com laser de baixa potência diminuiu dor e edema nos animais com trauma tendíneo, de forma dose-dependente.During the injured tendons healing process there is the inflammatory phase, which occurs in the presence, among other signs, of pain and edema. The antiinflammatory drug therapy receives some criticism, with respect to its deleterious effects for the

  2. Towards a Formal Model of the X86 ISA

    Science.gov (United States)

    2012-03-30

    implies (and (natp i) (natp j) (< i *2^27*)) 101 (equal (nth i (nth *mem-tablei* (initialize-mem-table j x86-64))) (if (<= j i) 1 (nth i (nth *mem...for a MOV instruction ; targeting a GPR ; see Intel 2.2.1.5, p. 2-14, and see AMD Vol. 3 Sec. 1.6 ; (p. 24), which restricts 64-bit immediates to "MOV...instructions that load ; GPRs ". And see AMD Vol. 1 Sec. 3.2.3.3 ("Immediate Operand Size"), which ; specifies those opcodes as "B8h through BFh

  3. Isa-Taska tegi koolitöö / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2004-01-01

    Esilinastus mängufilm "Täna öösel me ei maga" : stsenaristid Kristian Taska, Jaan Tätte : režissöör Ilmar Taska : operaator Istvan Borbas : produtsent Kristian Taska : peaosades Carmen Kass, Peter Franzen; Maria Avdjushko, Priit Võigemast : Taska Productions. Esilinastus 4. märts 2004. Lisatud Mart Laari ja Rain Tolki kommentaarid.

  4. Integrated Science Assessment (ISA) of Ozone and Related ...

    Science.gov (United States)

    EPA announced the availability of the final report, Integrated Science Assessment of Ozone and Related Photochemical Oxidants. This document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision regarding the adequacy of the current national ambient air quality standards for ozone to protect human health, public welfare, and the environment. Critical evaluation and integration of the evidence on health and environmental effects of ozone to provide scientific support for the review of the NAAQS for ozone.

  5. Search for Λ anti Λ heavy states at ISA

    International Nuclear Information System (INIS)

    Flaminio, V.; Lesnik, A.; Rehak, P.

    1977-01-01

    The possibility of observing ΛantiΛ heavy states using the Isabelle storage rings is discussed. Not many particles are known to date to decay into ΛantiΛ. The J/psi is a notable exception, with a branching ratio of about 0.2% (vs. 7% into e + e - and μ + μ - ). However, it is not inconceivable that higher mass states, produced at Isabelle energies, will have substantial branching fractions into ΛantiΛ. If this will indeed be the case, then one may think of getting additional information on the properties of the new states by taking advantage of the parity-violating Λ and antiΛ decays. Detectors, rate and background considerations, and methods of particle detection are discussed

  6. 13th international symposium on autoradiography (13th ISA '83)

    International Nuclear Information System (INIS)

    Strba, J.

    1983-01-01

    At the conference, 39 papers were heard all of which are included in INIS. Topics covered include: trends in development of solid state track detectors, theory and methods of quantitative autoradiography, equipment for autoradiographs processing and track counting, uses of autoradiography in research of semiconductors, in metallography and in biology

  7. President Ilves väisas metsapealinna / Arved Breidaks

    Index Scriptorium Estoniae

    Breidaks, Arved, 1975-

    2007-01-01

    President Toomas Hendrik Ilvese lühivisiidist Võrru. President lõunastas Roosisaarel Kuninga talus, külastas Sõmerpalu vallas puidutöötlusettevõtet GM Panels, osales laste metsateemaliste joonistuste näituse avamisel ning istutas Koreli oja äärsele puhkealale kuuse

  8. Baltimaade kunstiajaloo isa : Wilhelm Neumann 150 / Jevgeni Kaljundi

    Index Scriptorium Estoniae

    Kaljundi, Jevgeni, 1931-2011

    1999-01-01

    Wilhelm Neumann ئ iseõppija. Riias: ilmunud uurimused, töö oma projekti järgi ehitatud Läti kunstimuuseumi direktorina. Neumanni vaid Eesti kunstipärandit käsitlevad uurimused. Neumann ئ muinsuskaitsetegevuse algataja Baltimaadel, tema töid muinsuskaitse alal Eestis. W. Neumann arhitektina

  9. Rosiglitazone and Cardiovascular Risk – A Review | Isa | Bayero ...

    African Journals Online (AJOL)

    The thiazolidinediones (TZDs) are a class of oral drugs used for the management of type 2 diabetes mellitus and act as ligands for the transcription factor Peroxisome Proliferator-Activated Receptor gamma (PPARγ). Rosiglitazone, an example of TZD, is an anti-diabetic agent acting as a potent insulin sensitizer and is used ...

  10. Põrguvürst ja pruudi isa / Lauri Saaber

    Index Scriptorium Estoniae

    Saaber, Lauri

    2001-01-01

    Komöödiatest "Kohtumine äiaga" ("Meet the Parents") : režissöör Jay Roach : peaosas Robert DeNiro : Ameerika Ühendriigid 2000 ja "Võrgutav saatan" ("Bedazzled") : režissöör Harold Ramis : Ameerika Ühendriigid 2000

  11. Tendência da mortalidade perinatal em Belo Horizonte, 1984 a 2005 Tendencia de la mortalidad perinatal en Belo Horizonte, 1984 a 2005 Tendency of perinatal mortality in Belo Horizonte, 1984 to 2005

    Directory of Open Access Journals (Sweden)

    Eunice Francisca Martins

    2010-06-01

    Full Text Available O estudo objetivou analisar a tendência da mortalidade perinatal no município de Belo Horizonte no período de 1984 a 2005. A fonte dos dados foi o Sistema de Informação de Mortalidade (SIM. Realizou-se regressão linear simples para estimar a tendência de redução do percentual de informações ignoradas no SIM e das taxas de mortalidade. A melhora da qualidade da informação foi estatisticamente significativa apenas para a escolaridade materna e peso ao nascer. A redução média da mortalidade perinatal no período foi de 57,52%. O decréscimo da mortalidade perinatal nas duas últimas décadas em Belo Horizonte foi significativo, mas esforços devem ser direcionados no sentido de melhorar a completude do SIM para variáveis importantes na elaboração dos indicadores perinatais.El estudio apuntó a analizar la tendencia de la mortalidad perinatal en el distrito municipal de Belo Horizonte en el periodo de 1984 a 2005. La fuente de los datos era el Sistema de Información de Mortalidad. Tuvieron lugar la regresión lineal simple para estimar la tendencia de reducción del percentil de información desconocida en el sistema y de los impuestos de mortalidad. La mejora de la calidad de la información fue los significantes sólo para la educación maternal y peso al nacer. La reducción elemento de la mortalidad perinatal en el periodo era de 57,52%. La disminución de la mortalidad perinatal en las últimas dos décadas en Belo Horizonte era significante, pero deben dirigirse los esfuerzos en el sentido de mejorar el completude del sistema para las variables importantes en la elaboración del perinatais de los indicadores.The study aimed at to analyze the tendency of the mortality perinatal in the municipal district of Belo Horizonte in the period from 1984 to 2005. The source of the data was the System of Information of Mortality. Took place simple lineal regression to esteem the tendency of reduction of the percentile of unknown

  12. Tendências evolutivas dos cirurgiões de catarata presentes no IV Congresso Brasileiro de Catarata e Cirurgia Refrativa Evolutionary trends of cataract surgeons who attended the IV Brazilian Congress of Cataract and Refractive Surgery

    Directory of Open Access Journals (Sweden)

    Marcony Rodrigues de Santhiago

    2009-02-01

    Full Text Available OBJETIVO:Dar continuidade ao processo de atualização e aperfeiçoamento da cirurgia de catarata no Brasil, além de obter dados para uma análise comparativa das atuais tendências cirúrgicas nacionais e internacionais. MÉTODOS:Em maio de 2007, foram obtidos dados de 188 participantes de um congresso de Catarata e Cirurgia Refrativa através questionários autoaplicáveis, contendo perguntas objetivas a respeito da cirurgia de catarata. Análise estatística foi feita através teste T e Qui-quadrado. RESULTADOS: Observou-se que 95,8% dos participantes praticam a facoemulsificação, enquanto somente 4,2% preferem usar a técnica extracapsular convencional. Para 73,4% dos participantes, o bloqueio peribulbar é preferido em relação ao uso de anestésico tópico (20,2%. A técnica de facoemulsificação mais realizada é a de dividir e conquistar (32,0%. A hidroximetilcelulose foi o viscoelástico de escolha para 60,8% dos colaboradores. O aparelho de facoemulsificação mais usado pelos participantes foi o Infiniti® (24,0%, seguido pelo Legacy® (19,8%. CONCLUSÃO:Os resultados deste estudo foram consistentes com o que era esperado, tendo como base pesquisas semelhantes. Destaca-se um aumento considerável do número cirurgiões adeptos à facoemulsificação e tendências no sentido de maior utilização de incisões corneanas temporais e anestesia tópica.Purpose: To continue the updating and improving process of the cataract surgery in Brazil, through recently pulled out and documented registries. In addition, we want to obtain data for a comparative analysis of the current national and international surgical trends. METHODS:In May 2007, data were obtained from 188 participants of a Congress of Cataract and Refrative Surgery who answered simple and multiple-response questions about cataract surgery. Data were analyzed by statistic means of Chi-square test and T test. RESULTS:95.8% of respondents practice phacoemulsification, while only

  13. Homicídios na região das Américas: magnitude, distribuição e tendências, 1999-2009 Homicides in the Americas region: magnitude, distribution and trends, 1999-2009

    Directory of Open Access Journals (Sweden)

    Vilma Pinheiro Gawryszewski

    2012-12-01

    Full Text Available O objetivo do estudo foi descrever a magnitude e a distribuição da mortalidade por homicídios nas Américas e analisar suas tendências. Foram analisados óbitos por homicídios (X85 a Y09 e Y35 de 32 países das Américas, período 1999-2009, registrados no Sistema de Informações de Mortalidade/Organização Pan Americana da Saúde. Utilizou-se modelo binomial negativo para estudar as tendências. Cerca de 121.297 mortes por homicídios (89% homens e 11% mulheres ocorreram anualmente nas Américas, predominando as idades de 15 a 24 e de 25 a 39 anos. Em 2009, a taxa padronizada de homicídios da região foi 15,5/100.000. Os países com taxas/100.000 baixas foram Canadá (1,8, Argentina (4,4, Cuba (4,8, Chile (5,2 e Estados Unidos (5,8; e com taxas/100.000 altas foram El Salvador (62,9, Guatemala (51,2, Colômbia (42,5, Venezuela (33,2 e Porto Rico (25,8. Entre 1999-2009 as taxas da região permaneceram estáveis; aumentaram em nove países, como Venezuela (p The scope of this study was to describe the magnitude and distribution of deaths by homicide in the Americas and to analyze the prevailing trends. Deaths by homicide (X85 to Y09 and Y35 were analyzed in 32 countries of the Americas Region from 1999 to 2009, recorded in the Mortality Information System/Pan American Health Organization. A negative binomial model was used to study the trends. There were around 121,297 homicides (89% men and 11% women in the Americas, annually, predominantly in the 15 to 24 and 25 to 39 year age brackets. In 2009 the homicide age-adjusted mortality rate was 15.5/100,000 in the region. Countries with lower rates/100,000 were Canada (1.8, Argentina (4.4, Cuba (4.8, Chile (5.2, and the United States (5.8, whereas the highest rates/100,000 were in El Salvador (62.9, Guatemala (51.2, Colombia (42.5, Venezuela (33.2, and Puerto Rico (25.8. From 1999-2009, the homicide trend in the region was stable. They increased in nine countries: Venezuela (p<0.001, Panama (p

  14. Reconstrução coracoclavicular com enxerto tendíneo na luxação acromioclavicular crônica Coracoclavicular reconstruction using tendinous graft for chronic acromioclavicular joint dislocation

    Directory of Open Access Journals (Sweden)

    Jorge Henrique Assunção

    2011-01-01

    Full Text Available OBJETIVO: Apresentar os resultados radiográficos e funcionais de pacientes submetidos ao tratamento da luxação acromioclavicular crônica com reconstrução dos ligamentos coracoclaviculares com enxerto de tendão semitendíneo. MÉTODO: Quinze pacientes, entre abril de 2007 e junho de 2008, foram submetidos a reconstrução dos ligamentos coracoclaviculares com enxerto tendíneo. Dois pacientes foram excluídos do estudo por seguimento inadequado. Treze pacientes foram seguidos clinicamente e radiograficamente, em média, por 16 meses (12-26 meses. Os pacientes foram submetidos a avaliação clinica pré e pós-operatória, utilizando os escores Constant e UCLA. Radiografias pré e pós-operatórias foram comparadas. RESULTADOS: Neste grupo de 13 pacientes com seguimento mínimo de um ano, o escore Constant variou de 60,9 (26-88 na avaliação pré-operatória para 87 (60-98 na última avaliação no período pós-operatório. O escore UCLA foi de 16,8 (11-27 no pré operatório para 33 (29-35 na avaliação pós-operatória (p=0,001. No controle radiográfico com um ano de pós-operatório, encontramos 12 pacientes (92% com a distância coracoclavicular igual comparando o ombro operado ao contralateral. Todos os ombros operados apresentavam-se sem translação na direção antero-posterior no perfil axilar. CONCLUSÃO: O resultado funcional e radiográfico foi muito satisfatório nos pacientes submetidos à reconstrução das luxações acromioclaviculares crônicas, com baixo indice de recidiva. Nivel de Evidência IV, série de casos.OBJECTIVE: The aim of this study is to present the radiographic and functional results of patients undergoing treatment for chronic acromioclavicular dislocation with coracoclavicular ligament reconstruction using tendon graft. METHOD: Between 2007 and 2008, fifteen patients with chronic Rockwood type III through V acromioclavicular joint dislocations underwent reconstruction of the coracoclavicular ligaments

  15. Tendências de pesquisas brasileiras sobre mulheres mastectomizadas Tendencias en la investigación sobre la mujer brasileña sometida a mastectomía Trends in research with Brazilian women after mastectomy

    Directory of Open Access Journals (Sweden)

    Elisângela Braga de Azevedo

    2012-12-01

    Full Text Available Objetivou-se analisar as tendências das pesquisas realizadas no Brasil sobre mulheres mastectomizadas. Trata-se de um estudo bibliográfico de abordagem quantitativa, realizado de 15 de junho a 31 de julho de 2009. Para coleta dos dados empíricos utilizou-se um instrumento estruturado, posteriormente os dados foram tabulados, analisados, transformados em porcentagens e agrupados em uma tabela para facilitar a visualização das informações. A amostra foi constituída por resumos adquiridos através de busca eletrónica, utilizando-se as bases de dados da BIREME, LILACS, SciELO, MEDLINE e BDENF. Foram encontrados 111 artigos e após os critérios de inclusão chegou-se à amostra final de 69 artigos. Identificaram-se tendências a pesquisas qualitativas na maioria dos resumos, sendo o maior enfoque dado à reabilitação. A região que mais desenvolveu pesquisas foi a Sudeste, seguida pelo Nordeste. Muitos artigos não apresentavam dados informativos metodológicos essenciais para o entendimento do leitor, dificultando a busca nos referidos bancos de dados.Se ha fijado el objetivo de analizar las tendencias de la investigación realizada en Brasil en mujeres sometidas a mastectomías. Este es un estudio bibliográfico de enfoque cuantitativo, realizado entre el 15 junio y el 31 julio 2009. Para recolectar los datos empíricos, se utilizó un instrumento estructurado, posteriormente los datos fueron tabulados, analizados, transformados en porcentajes y se agrupan en una tabla para facilitar la visualización de la información. La muestra consistió en resúmenes obtenidos mediante una búsqueda electrónica, utilizando las bases de datos de BIREME, LILACS, SciELO, MEDLINE y BDENF. Se encontraron 111 artículos y tras aplicar los criterios de inclusión se llegó a una muestra final de 69 artículos. Se identificó una tendencia hacia la investigación cualitativa en la mayoría de los resúmenes, siendo que el foco principal fue dado a la

  16. Tendências gerenciais que podem levar a enfermagem a percorrer novos caminhos Tendencias gerenciales que pueden llevar a la enfermería a recorrer nuevos caminos Management trends that may lead nursing to new paths

    Directory of Open Access Journals (Sweden)

    Ana Maria Muller Magalhães

    2004-08-01

    Full Text Available As mudanças no contexto econômico e social têm determinado a necessidade de novas estratégias de gestão para as organizações. Na área de serviços, as instituições de Saúde e a Enfermagem têm sofrido o impacto dessas mudanças dentro dos seus processos de trabalho. Buscamos refletir sobre as novas tendências gerenciais e como elas podem influenciar a organização do trabalho de Enfermagem nos serviços de Saúde e as ações dos enfermeiros gerentes em estratégias que atendam aos desafios da profissão, num contexto social em transformação. Essas novas tendências têm apontado para a ênfase no desenvolvimento de organizações de aprendizagem, investimento no capital humano, na incorporação de novos conhecimentos e habilidades, buscando uma prática administrativa aberta, flexível e participativa, fundamentada na razão, na criatividade, sensibilidade e intuição.Las modificaciones en el contexto económico y social han determinado la necesidad de nuevas estrategias de gestión para las organizaciones. En el área de servicios, las instituciones de salud y la enfermería han sufrido el impacto de esas modificaciones dentro de sus procesos de trabajo. Buscamos reflexionar sobre las nuevas tendencias gerenciales y sobre la forma como las mismas pueden influenciar en la organización del trabajo de enfermería en servicios de salud y en las acciones de los enfermeros gerentes en estrategias que enfrenten los desafíos de la profesión en un contexto social en transformación. Esas nuevas tendencias han apuntado hacia el énfasis en el desarrollo de organizaciones de aprendizaje, inversión en capital humano, incorporación de nuevos conocimientos y habilidades en la búsqueda de una práctica administrativa abierta, flexible y participativa, fundamentada en la razón, en la creatividad, en la sensibilidad y en la intuición.The changes in the economic and social context have led to the need of new management strategies for

  17. Mortalidade por causas externas em crianças e adolescentes: tendências de 1979 a 1995 Child and adolescent mortality due to external causes: trends from 1979 to 1995

    Directory of Open Access Journals (Sweden)

    Maria Dilma de A Barros

    2001-04-01

    Full Text Available OBJETIVO: Analisar a magnitude e a tendência da mortalidade por grupos específicos de causas externas em crianças e adolescentes residentes no Recife, no período de 1979 a 1995. MÉTODOS: Foram utilizados os dados do Sistema de Informação em Mortalidade do Ministério da Saúde e da Secretaria de Saúde de Pernambuco. O grupo estudado, na faixa etária de 0-19 anos, representou 41,8% da população de Recife, em 1991. Utilizou-se o desenho ecológico exploratório tipo série temporal. Analisou-se a tendência para os coeficientes de mortalidade por causas externas e seus grupos específicos segundo sexo e grupo etário, por regressão linear simples. RESULTADOS E CONCLUSÕES: Na série temporal estudada, os coeficientes de mortalidade por causas externas mostraram crescimento, sobretudo por homicídios nos adolescentes, em que se observaram um aumento anual médio de 3,05 e um aumento relativo de 601, 3% ao longo da série. Em 1995, mais de 90% desses homicídios foram perpetrados por arma de fogo. Os dados revelam a magnitude do problema e a necessidade do seu enfrentamento, o qual precisa considerar a complexidade da determinação da violência.OBJECTIVE: To analyze the magnitude and trends of mortality due to external causes in specific age groups, from 0 to 19 years old in a population living in the city of Recife, Brazil, from 1979 to 1995. METHODS: Data from the Mortality Data System of the Ministry of Health and Health Department of Pernambuco State was used. The studied population, aged 0 to 19 years old, represented 41.8% of total city population in 1991. A time series exploratory ecological model was created to analyze trends in mortality coefficients due to external causes. Using simple linear regression these coefficients were assessed in specific age groups categorized by gender. RESULTS AND CONCLUSIONS: In the time series, mortality coefficients due to external causes showed an increasing trend, in particular due to

  18. Anisotropic inflation with derivative couplings

    Science.gov (United States)

    Holland, Jonathan; Kanno, Sugumi; Zavala, Ivonne

    2018-05-01

    We study anisotropic power-law inflationary solutions when the inflaton and its derivative couple to a vector field. This type of coupling is motivated by D-brane inflationary models, in which the inflaton, and a vector field living on the D-brane, couple disformally (derivatively). We start by studying a phenomenological model where we show the existence of anisotropic solutions and demonstrate their stability via a dynamical system analysis. Compared to the case without a derivative coupling, the anisotropy is reduced and thus can be made consistent with current limits, while the value of the slow-roll parameter remains almost unchanged. We also discuss solutions for more general cases, including D-brane-like couplings.

  19. Sol-gel derived sorbents

    Science.gov (United States)

    Sigman, Michael E.; Dindal, Amy B.

    2003-11-11

    Described is a method for producing copolymerized sol-gel derived sorbent particles for the production of copolymerized sol-gel derived sorbent material. The method for producing copolymerized sol-gel derived sorbent particles comprises adding a basic solution to an aqueous metal alkoxide mixture for a pH.ltoreq.8 to hydrolyze the metal alkoxides. Then, allowing the mixture to react at room temperature for a precalculated period of time for the mixture to undergo an increased in viscosity to obtain a desired pore size and surface area. The copolymerized mixture is then added to an immiscible, nonpolar solvent that has been heated to a sufficient temperature wherein the copolymerized mixture forms a solid upon the addition. The solid is recovered from the mixture, and is ready for use in an active sampling trap or activated for use in a passive sampling trap.

  20. Situação de saúde da criança em área da região sul do Brasil, 1980-1992: tendências temporais e distribuição espacial

    Directory of Open Access Journals (Sweden)

    Cesar G. Victora

    1994-12-01

    Full Text Available Embora as estatísticas vitais sejam de fundamental importância para o planejamento e avaliação das ações de saúde, são poucos os Estados brasileiros que dispõem de sistema de registro com cobertura e agilidade suficiente para atingir estas metas. Objetivou, portanto, analisar os dados gerados no Rio Grande do Sul, Brasil, para descrever tendências temporais e distribuição espacial de indicadores de saúde infantil, incluindo os coeficientes de mortalidade infantil e de mortalidade proporcional de menores de um ano, prevalência de baixo peso ao nascer, e cobertura vacinal. Entre 1980 e 1992, observaram-se reduções marcantes na mortalidade infantil (de 39,0 para 19,3 por mil e na mortalidade proporcional de menores de um ano (de 13,9% para 5,9%. A prevalência de baixo peso ao nascer mostrou-se estável entre 8 e 10%, tendo mesmo sido observado discreto aumento até 1991. A cobertura de vacina tríplice oscilou marcadamente de ano a ano, entre 79% e 99%. Houve forte correlação, ao nível de Delegacias Regionais de Saúde, entre mortalidade infantil e baixo peso ao nascer. Os 4 indicadores estudados foram combinados de forma a construir um escore para identificar as Delegacias de Saúde com maiores necessidades de intervenções sanitárias. A região sul do Estado, caracterizada pela presença de grandes latifúndios, mostrou os piores índices de saúde infantil.

  1. Diagnóstico clínico da ruptura do tendão subescapular com a manobra semiológica bear hug Clinical diagnosis of subscapularis tendon tear using the bear hug semiological maneuver

    Directory of Open Access Journals (Sweden)

    Márcio Schiefer

    2012-10-01

    Full Text Available OBJETIVO: Avaliar a manobra bear hug no diagnóstico clínico da lesão do tendão subescapular e compará-la com manobras previamente descritas (lift-off, Napoleão e belly press. MÉTODOS: Foram analisados 49 pacientes com lesão do manguito rotador, submetidos à artroscopia para reparo da lesão e avaliados previamente pelas manobras semiológicas citadas. RESULTADOS: Os valores diagnósticos obtidos para o teste bear hug foram os seguintes: sensibilidade = 75%; especificidade = 56%; VPP = 62%; VPN = 70%; acurácia = 65%. CONCLUSÃO: Os maiores valores de sensibilidade e valor preditivo negativo foram obtidos com o bear hug. O maior valor de especificidade foi encontrado no teste lift-off. O teste belly press forneceu os maiores valores de especificidade, valor preditivo positivo e acurácia.OBJECTIVE: To evaluate the Bear Hug maneuver for clinically diagnosing subscapularis tendon tears, and compare this with other maneuvers described previously (Lift-off, Napoleon and Belly Press. METHODS: Forty-nine patients with rotator cuff injuries who had undergone arthroscopy to repair the injury and had previously been assessed using the semiological maneuvers mentioned above were evaluated. RESULTS: The diagnostic values obtained for the Bear Hug test were as follows: sensitivity 75%, specificity 56%, positive predictive value 62%, negative predictive value 70% and accuracy 65%. CONCLUSION: The highest sensitivity and negative predictive value values were obtained with the Bear Hug test. The highest specificity value was seen with the Lift-off test. The Belly press test gave the greatest specificity, positive predictive and accuracy values.

  2. Tendências de gerenciamento de unidades de saúde e de pessoas Tendencias de gerenciamiento de unidades de salud y de personas Health care units and human resources management trends

    Directory of Open Access Journals (Sweden)

    Adriana Maria André

    2013-02-01

    Full Text Available OBJETIVO: Identificar que fatores produzem novas tendências no gerenciamento das unidades básicas de saúde e mudanças nos modelos de gestão. MÉTODOS: Estudo prospectivo com dez gestores de unidades de saúde e dez especialistas da área de saúde de São Paulo, SP, em 2010. Foi adotada a metodologia Delphi. Foram utilizadas quatro rodadas para a coleta de dados, três quantitativas e a quarta qualitativa. Nas três primeiras foram levantadas as tendências de mudança nos modelos de gestão; no perfil do gestor e nas competências requeridas para a função, foi utilizado o teste estatístico de Mann Whitney. A quarta rodada ocorreu por meio de um painel com os envolvidos, tendo sido escolhida a análise temática. RESULTADOS: Foram identificados os principais fatores que estão impulsionando o gerenciamento das unidades básicas de saúde, como as mudanças nos modelos de gestão. Foi consenso de que as dificuldades no gerenciamento das equipes e nas políticas influemciam nesse processo. Verificou-se que os gestores estão a par das tendências do macrocontexto com o advento das organizações sociais de saúde, mas ainda não estão se antecipando nas ações institucionais. CONCLUSÕES: A formação acadêmica deve ser revista não só quanto aos conteúdos, mas quanto ao desenvolvimento desses profissionais. O recrutamento, a seleção, o desenvolvimento e a avaliação devem ser norteados por essas competências alinhadas à missão, à visão, aos valores e aos modelos de gestão das organizações no contexto do Sistema Único de Saúde.OBJETIVO: Identificar los factores que producen nuevas tendencias en el gerenciamiento de las unidades básicas de salud y cambios en los modelos de gestión. MÉTODOS: Estudio prospectivo con diez gestores de unidades de salud y diez especialistas del área de salud de Sao Paulo, SP- Brasil, en 2010. Se adoptó la metodología Delphi. Se utilizaron cuatro circulaciones para la colecta de datos

  3. Synthesis of 2-phosphaadamantane derivatives

    International Nuclear Information System (INIS)

    Zemlyanoi, V.N.; Aleksandrov, A.M.; Kukhar', V.P.

    1986-01-01

    The authors describe the synthesis and properties of 2-phosphadamantane derivatives. For the synthesis of 2-phosphaadamantane derivatives they decided to use the methodology of the synthesis of 2-thiaadamantane. The IR spectra were determined on CHCl 3 solutions with a Specord 711R spectrometer, the PMR spectra were determined on Tesla BS-467 (60 MHz) and Bruker WP-200 (200 MHz) spectrometers, external standard hexamethyldisiloxane, the 31 P NMR spectra were determined on Tesla BS-487 C (30 MHz) and Bruker WP-200 (81 MHz) spectrometers, external standard 85% phosphoric acid, and the mass spectra were determined on an MS-1302 spectrometer

  4. Bounded Densities and Their Derivatives

    DEFF Research Database (Denmark)

    Kozine, Igor; Krymsky, V.

    2009-01-01

    This paper describes how one can compute interval-valued statistical measures given limited information about the underlying distribution. The particular focus is on a bounded derivative of a probability density function and its combination with other available statistical evidence for computing ...... quantities of interest. To be able to utilise the evidence about the derivative it is suggested to adapt the ‘conventional’ problem statement to variational calculus and the way to do so is demonstrated. A number of examples are given throughout the paper....

  5. Risk Factors in Derivatives Markets

    Directory of Open Access Journals (Sweden)

    Raimonda Martinkutė-Kaulienė

    2015-02-01

    Full Text Available The objective of the article is to analyse and present the classification of risks actual to derivative securities. The analysis is based on classical and modern literature findings and analysis of newest statistical data. The analysis led to the conclusion, that the main risks typical for derivatives contracts and their traders are market risk, liquidity risk, credit and counterparty risk, legal risk and transactions risk. Pricing risk and systemic risk is also quite important. The analysis showed that market risk is the most important kind of risk that in many situations influences the level of remaining risks.

  6. Analytical application of derivative spectrophotometry

    Directory of Open Access Journals (Sweden)

    VIOLETA M. STEFANOVIC

    2000-07-01

    Full Text Available 1. Introduction 2. Basic characteristics of derivative spectrophotometry 2.1. Increase of spectra resolution 2.2. Elimination of the influence of baseline shift and matrix interferences 2.3. Enhancement of the detectability of minor spectral features 2.4. Precise determination of the positions of absorption maxima 2.5. Signal-to-noise ratio (SNR 2.6. Quantitative analysis 3. Analytical applications 3.1. Inorganic analysis 3.2. Organic and pharmaceutical analysis 3.3. Analysis of food and water 3.4. Application of derivative spectrophotometry for the determination of equilibrium constants

  7. Derived equivalences for group rings

    CERN Document Server

    König, Steffen

    1998-01-01

    A self-contained introduction is given to J. Rickard's Morita theory for derived module categories and its recent applications in representation theory of finite groups. In particular, Broué's conjecture is discussed, giving a structural explanation for relations between the p-modular character table of a finite group and that of its "p-local structure". The book is addressed to researchers or graduate students and can serve as material for a seminar. It surveys the current state of the field, and it also provides a "user's guide" to derived equivalences and tilting complexes. Results and proofs are presented in the generality needed for group theoretic applications.

  8. Comparative analysis of amino acids and amino-acid derivatives in protein crystallization

    International Nuclear Information System (INIS)

    Ito, Len; Shiraki, Kentaro; Yamaguchi, Hiroshi

    2010-01-01

    New types of aggregation suppressors, such as amino acids and their derivatives, were focused on as fourth-component additives. Data were obtained that indicated that the additives promote protein crystallization. Optimal conditions for protein crystallization are difficult to determine because proteins tend to aggregate in saturated solutions. This study comprehensively evaluates amino acids and amino-acid derivatives as additives for crystallization. This fourth component of the solution increases the probability of crystallization of hen egg-white lysozyme in various precipitants owing to a decrease in aggregation. These results suggest that the addition of certain types of amino acids and amino-acid derivatives, such as Arg, Lys and esterified and amidated amino acids, is a simple method of improving the success rate of protein crystallization

  9. derivatives: Synthesis and antimicrobial evaluation

    Indian Academy of Sciences (India)

    cal activity study revealed that all compounds showed promising activities and bis-(1H-2-benzopyran-1-one) derivatives (5) ...... A and Galvez J 2004 Planta Med. 70 315. 6. ... Ante N, Erik De C, Jan B and Mladen M 2011 Molecules. 16 6023.

  10. Second derivative spectrophotometric determination of ...

    African Journals Online (AJOL)

    A new, simple, rapid, wide applicable range and reliable second derivative spectrophotometric method has been developed for determination of cyclophosphamide (CP) in bulk and pharmaceutical dosage forms. Calibration graph is linear in the concentration range of 25 - 200 μg/ml of CP with 10 μg/ml of detection limit and ...

  11. Hypoxanthine Derivatives in Experimental Infections

    Directory of Open Access Journals (Sweden)

    Claudio De Simone

    1992-01-01

    ability of ST 789 to increase interleukin-6 production, suggest that monocyte/macrophages are likely to be the main cellular target of the immunomodulating activity of ST 789. Finally, in the presentln vivo study, hypoxanthine derivatives did not enhance the mean survival time of tumour-bearing immunosuppressed mice.

  12. Radiological protection optimization using derivatives

    International Nuclear Information System (INIS)

    Freitas Acosta Perez, C. de; Sordi, G.M.A.A.

    2006-01-01

    The aim of this paper is to provide a different approach related to the integral cost-benefit and extended cost-benefit analysis used in the decision-aiding techniques. In the ICRP publication 55 the annual protection cost is envisaged as a set of points, each of them representing an option, linked by a straight line. The detriment cost function is considered a linear function whose angular coefficient is determined by the alpha value. In this paper the uranium mine example considered in the ICRP publication 55 was used. But the potential curve was introduced both in the integral cost benefit analysis and in the extended cost-benefit analysis, which the individual dose distribution attribute is added. The result was obtained using derivatives. The detriment cost, Y, is not necessary because the alpha value is known. The Y derivative dS/dY is the alpha value itself and so, the attention is directed to the derivative -dX/dS on the points that, along with the alpha value, present the optimum option. The results makes clear that the prevailing factor in the optimum option selection is the alpha value imputed, and those a single alpha value, as suggested now, probably as little efficiency on the optimization process. Obtaining a curve for the alpha value and using the derivative technique introduced in this paper, the analytical solution is more convenient and reliable compared to the one used now. (authors)

  13. Alchemical derivatives of reaction energetics

    Science.gov (United States)

    Sheppard, Daniel; Henkelman, Graeme; von Lilienfeld, O. Anatole

    2010-08-01

    Based on molecular grand canonical ensemble density functional theory, we present a theoretical description of how reaction barriers and enthalpies change as atoms in the system are subjected to alchemical transformations, from one element into another. The change in the energy barrier for the umbrella inversion of ammonia is calculated along an alchemical path in which the molecule is transformed into water, and the change in the enthalpy of protonation for methane is calculated as the molecule is transformed into a neon atom via ammonia, water, and hydrogen fluoride. Alchemical derivatives are calculated analytically from the electrostatic potential in the unperturbed system, and compared to numerical derivatives calculated with finite difference interpolation of the pseudopotentials for the atoms being transformed. Good agreement is found between the analytical and numerical derivatives. Alchemical derivatives are also shown to be predictive for integer changes in atomic numbers for oxygen binding to a 79 atom palladium nanoparticle, illustrating their potential use in gradient-based optimization algorithms for the rational design of catalysts.

  14. Radiolabeled derivatives of folic acid

    International Nuclear Information System (INIS)

    1980-01-01

    Derivatives of folic acid are described, in which the α-carboxyl group is substituted with an amino compound having an aromatic or heterocyclic ring substituent which is capable of being radiolabelled. Particularly mentioned as a radiolabel is 125 I. (author)

  15. Second derivative spectrophotometric determination of ...

    African Journals Online (AJOL)

    Hemn

    2013-11-13

    Nov 13, 2013 ... olanzapine in pharmaceutical formulation.Int.J.ChemTech. Res.2(1):756-761. Stanisz B, Paszun S, Lesniak M (2009). Validation of UV derivative spectrophotometric method for determination of benazepril hydrochloride in tablets and evaluation of its stability.ActaPoloniaePharmaceutica-Drug Research.

  16. Novel bisstyryl derivatives of bakuchiol

    DEFF Research Database (Denmark)

    Reddy, Mallepally V; Thota, Niranjan; Sangwan, Payare L

    2010-01-01

    Novel bisstyryl derivatives of bakuchiol using Heck coupling reaction as the key step were synthesized and screened against a panel of six oral cavity pathogens for their antimicrobial activity. Four compounds (9-12) showed two to fourfold and four to eightfold better activity (MIC 0.25-16 microg...

  17. Push-outs of derivations

    DEFF Research Database (Denmark)

    Grønbæk, Niels

    2008-01-01

    Let A be a Banach algebra and let X be a Banach A-bimodule. In studying H¹(A,X) it is often useful to extend a given derivation D: A->X to a Banach algebra B containing A as an ideal, thereby exploiting (or establishing) hereditary properties. This is usually done using (bounded/unbounded) approx...

  18. Asymptotic aspect of derivations in Banach algebras

    Directory of Open Access Journals (Sweden)

    Jaiok Roh

    2017-02-01

    Full Text Available Abstract We prove that every approximate linear left derivation on a semisimple Banach algebra is continuous. Also, we consider linear derivations on Banach algebras and we first study the conditions for a linear derivation on a Banach algebra. Then we examine the functional inequalities related to a linear derivation and their stability. We finally take central linear derivations with radical ranges on semiprime Banach algebras and a continuous linear generalized left derivation on a semisimple Banach algebra.

  19. Higher-derivative generalization of conformal mechanics

    Science.gov (United States)

    Baranovsky, Oleg

    2017-08-01

    Higher-derivative analogs of multidimensional conformal particle and many-body conformal mechanics are constructed. Their Newton-Hooke counterparts are derived by applying appropriate coordinate transformations.

  20. As tendências pedagógicas e a prática educativa nas ciências da saúde Pedagogical approaches and educational practices in health sciences

    Directory of Open Access Journals (Sweden)

    Adriana Lenho de Figueiredo Pereira

    2003-10-01

    Full Text Available As práticas educativas são amplamente utilizadas na área da saúde, tanto na formação contínua dos profissionais que atuam nesta área quanto no campo da educação em saúde para a população em geral. A interseção destes dois campos de conhecimento humano se dá através do desenvolvimento de práticas educativas norteadas por um conjunto de representações de homem e de sociedade que se quer efetivar. Essas representações são demonstradas através da discussão dos processos de ensino-aprendizagem utilizados nas tendências pedagógicas mais dominantes em nosso meio: a pedagogia tradicional, renovada, por condicionamento e a libertadora. A partir dos princípios, métodos e conseqüências ao nível individual e social de cada pedagogia apresentada, concluímos que a pedagogia libertadora pode produzir melhores resultados que as demais correntes pedagógicas estudadas, por possibilitar a participação ativa do educando no processo da aprendizagem, propiciando o desenvolvimento contínuo das habilidades humanas tanto da clientela quanto dos trabalhadores da área de saúde.Educational practices are widely used in the health field, both in continuing education for health professionals and health education for the general population. These two fields intersect through the development of educational knowledge oriented by a set of target representations of man and society. Such representations are demonstrated by teaching/learning processes in the four main pedagogical trends in Brazil: traditional, renewed, conditioning-based, and liberating (or the Paulo Freire approach. Based on their respective principles, methods, and individual and social consequences, we contend that liberating pedagogy can produce better results than the others by allowing the student's active participation in the learning process, thus fostering continuous development of human skills in both the health services clientele and health workers.

  1. Tendências do diabetes mellitus no Brasil: o papel da transição nutricional Trends in diabetes mellitus in Brazil: the role of the nutritional transition

    Directory of Open Access Journals (Sweden)

    Daniela Saes Sartorelli

    2003-01-01

    Full Text Available A prevalência do diabetes mellitus tipo 2 tem se elevado vertiginosamente e espera-se ainda um maior incremento. Na América Latina há uma tendência do aumento da freqüência entre as faixas etárias mais jovens, cujo impacto negativo sobre a qualidade de vida e a carga da doença ao sistema de saúde é relevante. O aumento das taxas de sobrepeso e obesidade associado às alterações do estilo de vida e ao envelhecimento populacional, são os principais fatores que explicam o crescimento da prevalência do diabetes tipo 2. As modificações no consumo alimentar da população brasileira - baixa freqüência de alimentos ricos em fibras, aumento da proporção de gorduras saturadas e açúcares da dieta - associadas a um estilo de vida sedentário compõem um dos principais fatores etiológicos da obesidade, diabetes tipo 2 e outras doenças crônicas. Programas de prevenção primária do diabetes vêm sendo desenvolvidos em diversos países, cujos resultados demonstram um impacto positivo sobre a qualidade de vida da população.Prevalence of type 2 diabetes mellitus has increased rapidly and is expected to increase even further. In Latin America countries there is an upward trend among the younger age groups, with a major negative impact on the quality of life and burden of the disease for the health care system. Increasing rates of overweight and obesity associated with lifestyle changes and aging of the population are the main contributing factors to the increasing prevalence of type 2 diabetes. Dietary shifts in the Brazilian population (low frequency of fiber-rich foods and heavy consumption of saturated fatty acids and sugars and sedentary lifestyle are the main risk factors for obesity, type 2 diabetes, and other chronic diseases. Diabetes prevention programs are being promoted in several countries with results showing improvement in quality of life.

  2. Tendências curriculares nas escola de formação técnica para o SUS Curricular trends in the schools providing technical training for the SUS

    Directory of Open Access Journals (Sweden)

    Isabel Brasil Pereira

    2004-03-01

    Full Text Available Este artigo mapeia e analisa tendências curriculares das escolas de educação profissional em nível técnico para o Sistema Único de Saúde (SUS. Trata-se de, mediante resgate da literatura sobre currículo, analisar a organização, a seleção e a hierarquização de conhecimentos, fatores que estão articulados às lutas entre projetos educacionais. É significativo para o estudo o fato de que a educação profissional é chamada a responder às questões advindas do mundo do trabalho. Neste sentido, recuperam-se contradições existentes no campo educacional, como a idéia de que, por um lado, é verdade que 'a experiência ensina', consistindo em ponto significativo para a aprendizagem, mas que, por outro, é necessário fazer a crítica na fé incomensurável na experiência cotidiana como um processo que, por si só, garante a aprendizagem qualificada.This article outlines and analyses the curricular trends in the schools providing professional technical education for the Brazilian Health System's workers (Sistema Único de Saúde - SUS. With the help of a close survey of the literature on curricula, it analyses the organization, selection and hierarchical gradation of knowledge, all of which are connected with the struggle between educational projects. For the study, the fact that professional education is called to respond to the issues originating in the labour world is highly significant. In this sense, we attempted to rescue the contradictions existing in the educational field, such as, for instance, the idea that, even if it is true that "experience is the best teacher" and an important stage in the learning process, it is also important to criticize an exaggerated faith on the everyday experience and the presumption that experience can, by itself, provide qualified learning.

  3. Metadados digitais: revisão bibliográfica da evolução e tendências por meio de categorias funcionaisDigital metadata: bibliographical review on evolution and trends using functional categories

    Directory of Open Access Journals (Sweden)

    Luiz Fernando de Barros Campos

    2007-01-01

    Full Text Available Revisão bibliográfica sobre metadados digitais no campo da ciência da informação, objetivando precisar as várias funcionalidades dos metadados. Empregando-se uma técnica de análise de conteúdo temática, constatou-se a recorrência de tecnologias como XML, RDFS, ontologias, data warehouses, Web Semântica, serviços Web, entre outras, e de dez categorias relativas às funções dos metadados que fundamentavam os textos examinados. Com suporte na análise temática, adotando-se uma perspectiva técnica e histórica, relacionaram-se as categorias funcionais às tecnologias e mostrou-se como as categorias são tratadas em dezenove dos artigos revisados, destacando-se as ênfases empregadas e a convergência dos temas. Notou-se que trabalhos e tecnologias que versam sobre padrões e modelos para preservação digital adotam perspectivas mais abrangentes e integradas, incorporando todas ou quase todas as categorias. Com base nos resultados, foram comentadas tendências e questões latentes percebidas na revisão bibliográfica, e sugeridas abordagens e metodologias para a análise de metadados e das tecnologias relacionadas.By means of a bibliographical review on digital metadata in the information science field, aiming to distinguish the various functionalities of metadata and employing thematic content analysis, it was noticed the recurrence of technologies like XML, RDFS, ontology, data warehouses, semantic Web, Web services, among others, and of certain categories connected to metadata functions that grounded the examined works. Based on these findings, adopting a technical and historical approach, the functional categories were related to the technologies and it was showed how the categories wereexpounded in 19 texts selected from the review. It was observed that studies and technologies that deal with models and standards for digital preservation adopt more comprehensive and integrated perspectives, encompassing all or nearly all

  4. The precision of the NDVI derived from AVHRR observations

    International Nuclear Information System (INIS)

    Roderick, M.; Smith, R.; Cridland, S.

    1996-01-01

    Vegetation studies using NOAA-AVHRR data have tended to focus on the use of the normalized difference vegetation index (NDVI). This unitless index is computed using near-infrared and red reflectances, and thus has both an accuracy and precision. This article reports on a formal statistical framework for assessing the precision of the NDVI derived from NOAA-AVHRR observations. The framework is based on the “best possible” precision concept, which assumes that signal quantization is the only source of observational error. While the radiance resolution of a spectral observation is essentially fixed by the instrument characteristics, the reflectance resolution is the radiance resolution divided by the cosine of the solar zenith angle. Using typical solar zenith angles for AVHRR image acquisitions over Australia, ± 0.01 NDVI units is typically with “best possible” precision attainable in the NDVI, although this degrades significantly over dark targets, and at large solar zenith angles. Transforming the computed NDVI into a single byte for disk storage results in little or no loss of precision. The framework developed in this article can be adapted to estimate the “best possible” precision of other vegetation indices derived using data from other remote sensing satellites. (author)

  5. Gênero e saúde: perfil e tendências da produção científica no Brasil Gender and health: profile and trends of the scientific production in Brazil

    Directory of Open Access Journals (Sweden)

    Estela M L Aquino

    2006-08-01

    Full Text Available As diferenças em saúde entre homens e mulheres têm sido objeto de grande interesse, mas as interpretações tendem a ser naturalizadas e essencialistas. Os estudos de gênero têm criticado essa literatura, oferecendo alternativas de análise promissoras. Assim realizou-se estudo com o objetivo de descrever o perfil e as tendências da atividade científica sobre gênero e saúde no Brasil. Foram utilizados dados do Diretório de Grupos de Pesquisa do Conselho Nacional de Desenvolvimento Científico e Tecnológico, do Banco de Teses da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, e quatro periódicos da área da saúde. Foram identificados 51 grupos com pelo menos uma linha de pesquisa na temática, com concentração regional e institucional. Os resultados confirmam o crescimento acentuado da produção científica, sendo localizadas 98 dissertações, 42 teses e 665 artigos sobre gênero e saúde. As mulheres são autoras de 86,0% das teses e 89,0% das dissertações e 70,5% dos artigos. A maioria dos trabalhos acadêmicos foi divulgada na década de 2000, quando ocorreu também ampliação das questões abordadas. Os temas podem ser reunidos em cinco subgrupos: reprodução e contracepção; violência de gênero; sexualidade e saúde, com ênfase nas DST/Aids; trabalho e saúde, incluindo trabalho doméstico e trabalho noturno; outros temas emergentes ou pouco explorados. São grandes os desafios políticos, epistemológicos e metodológicos para consolidação dos avanços. A perspectiva de gênero oferece amplas possibilidades de enriquecimento da reflexão teórica na saúde coletiva, podendo-se somar a outros esforços intelectuais e políticos para a compreensão da saúde e seus determinantes na luta contra as desigualdades e pela justiça social.The differences in health between men and women have been object of great interest, but interpretations tend to be naturalized and essentialists. Gender-oriented studies

  6. Tendência secular do peso ao nascer na cidade de São Paulo (1976-1998 Secular trends in birth weight in S. Paulo city, Brazil (1976-1998

    Directory of Open Access Journals (Sweden)

    Carlos Augusto Monteiro

    2000-12-01

    Full Text Available OBJETIVO: Resgatar a tendência secular da distribuição do peso ao nascer na cidade de São Paulo, SP, bem como examinar suas possíveis causas, com base em dados coletados por dois inquéritos domiciliares sobre condições de saúde na infância realizados em 1984/85 e em 1995/96, complementados por informações procedentes de levantamento de prontuários de maternidades e por informações do Sistema Estadual de Declarações de Nascidos Vivos. MÉTODOS: Os inquéritos domiciliares estudaram amostras probabilísticas da população infantil de São Paulo com idade inferior a cinco anos (n=1.016 em 1984/85; n=1.280 em 1995/96. O levantamento de prontuários estudou uma amostra probabilística dos partos ocorridos nas maternidades da cidade no ano de 1976 (n=5.734. As declarações de nascidos vivos referem-se às coortes de crianças nascidas na cidade entre 1993 e 1998 (cerca de 200 mil crianças por ano. O estudo da distribuição social do peso ao nascer levou em conta a renda familiar per capita e a escolaridade materna. A estratégia analítica para estudar os determinantes da tendência secular do peso ao nascer empregou modelos hierárquicos de causalidade, análises multivariadas de regressão e procedimentos análogos aos utilizados para calcular riscos atribuíveis populacionais. RESULTADOS/CONCLUSÕES: A distribuição do peso ao nascer na cidade de São Paulo (média de 3.160 g com 8,9% de pesos OBJECTIVE: Data from two household surveys on infant and child health status undertaken in the mid-80s and mid-90s, complemented with previous data collected from maternity hospitals records and more recent data provided by the state system on birth registries, allowed to characterize and analyse secular trends in birth weight in the city of S. Paulo, Brazil. METHODS: The household surveys included random samples of children under 5 years old (n=1,016 children in 1984-85 and n=1,280 children in 1995-96. A random sample of births that

  7. O ensino secundário militar na contramão das tendências do Império -Secondary military education in the 19th century a gainst the general trend

    Directory of Open Access Journals (Sweden)

    Claudia Alves

    2011-03-01

    Full Text Available Resumo O presente artigo tem como objetivo apresentar a trajetória de construção dos estudos preparatórios à Escola Militar, entre as décadas de 1850 e 1870, quando os esforços de preparação e qualificação de quadros, no âmbito do exército brasileiro, sã potencializados pelas exigências da profissionalização própria dos exércitos do século XIX. O reforço à formação de nível superior, consubstanciado na Lei de 1850, que regulamentava a ascensão na carreira, vinculando-a aos cursos da Escola, reflete-se na organização de estudos preparatórios que, no espaço de duas décadas, tendem a transformar-se num curso seriado de três anos. Esse movimento,quando confrontado com os dados existentes para o ensino secundário do Império, encontra-se na contramão da tendência geral, que aponta para a fragmentação e pulverização desse nível de estudos. Palavras-chave: ensino secundário; escola militar; século XIX.   SECONDARY MILITARY EDUCATION IN THE 19TH CENTURY AGAINST THE GENERAL TREND Abstract This article aims at presenting the steps involved in building preparatory studies for the Military School, between the decades of 1850 and 1870, when the efforts of staff preparation and qualification, within the Brazilian army, were enhanced by the demands of professional armies, in the nineteenth century. The strengthening of higher education, embodied in the Act of 1850, regulating the criteria for advancing in the military career, linking it to the School courses, reflects on the organization of preparatory studies that tend to become a three-year course, within the next two decades. This movement, when confronted with existing secondary education data on the Brazilian imperial period, goes against the general trend, pointing at the fragmentation and pulverization of such level of studies. Keywords: secondary school; military school; nineteenth century.   LA ENSEÑANZA SECUNDARIA MILITAR EN LACONTRAMANO DE LAS TENDENCIAS

  8. Derivatives in energy project finance

    International Nuclear Information System (INIS)

    Spencer, Lloyd

    1999-01-01

    This chapter focuses on risk management of merchant power generation projects and describes project finance as balancing risk and reward over time. The historical background to risk management is traced, and the case for derivatives in energy project finance is put forward with the hedging of forward output, and forwards and power purchase agreements discussed. Current and prospective usage, and the implementation issues of market liquidity, margin calls, letters of credit, derivative counterparty credit risk, and accounting policy are considered. A detailed example of a gas-fired plant in the US is presented with details given of the distribution of project earnings before tax. Oil field operating cashflows are examined, with reserved flow models, leverage effects, and price hedging addressed

  9. Diagnostic radio labelled polysaccharide derivatives

    International Nuclear Information System (INIS)

    Milbrath, D.S.; Ferber, R.H.; Barnett, W.E.

    1982-01-01

    A radiopharmaceutical compound for diagnosing blood clots is claimed. It is the reaction product of a compound characterized by a water-soluble polysaccharide moiety having an average of at least 0.25 anionic group per monosaccharide unit, and at least one chelating group derived from the group consisting of amino acids, substituted cyclic acid anhydrides, and carbon disulfide; and a radioactive tracer metal compound selected from In-111, Tc-99m, Cr-51, Ga-68, and a reduced pertechnetate compound

  10. Derivation of Hamiltonians for accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Symon, K.R.

    1997-09-12

    In this report various forms of the Hamiltonian for particle motion in an accelerator will be derived. Except where noted, the treatment will apply generally to linear and circular accelerators, storage rings, and beamlines. The generic term accelerator will be used to refer to any of these devices. The author will use the usual accelerator coordinate system, which will be introduced first, along with a list of handy formulas. He then starts from the general Hamiltonian for a particle in an electromagnetic field, using the accelerator coordinate system, with time t as independent variable. He switches to a form more convenient for most purposes using the distance s along the reference orbit as independent variable. In section 2, formulas will be derived for the vector potentials that describe the various lattice components. In sections 3, 4, and 5, special forms of the Hamiltonian will be derived for transverse horizontal and vertical motion, for longitudinal motion, and for synchrobetatron coupling of horizontal and longitudinal motions. Hamiltonians will be expanded to fourth order in the variables.

  11. Financial Derivatives (Based on Two Supports Evaluation

    Directory of Open Access Journals (Sweden)

    Tiberiu Socaciu

    2016-07-01

    Full Text Available In this paper we build a PDE like Black-Scholes equation in hypothesis of a financial derivative that is dependent on two supports (usual is dependent only on one support, like amoption based on gold, when national currency has a great float.Keywords: Financial derivatives, derivatives evaluation, derivatives based on two supports, extended Itō like lemma.

  12. 12 CFR 403.4 - Derivative classification.

    Science.gov (United States)

    2010-01-01

    ... SAFEGUARDING OF NATIONAL SECURITY INFORMATION § 403.4 Derivative classification. (a) Use of derivative classification. (1) Unlike original classification which is an initial determination, derivative classification... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Derivative classification. 403.4 Section 403.4...

  13. Clearing and settlement of exchange traded derivatives

    OpenAIRE

    John McPartland

    2009-01-01

    Derivatives are a class of financial instruments that derive their value from some underlying commodity, security, index, or other asset. Futures and options are common forms of derivatives. This article explains how clearing and settlement systems for exchange traded derivatives work.

  14. Disponibilidade de "açúcares de adição" no Brasil: distribuição, fontes alimentares e tendência temporal Availability of added sugars in Brazil: distribution, food sources and time trends

    Directory of Open Access Journals (Sweden)

    Renata Bertazzi Levy

    2012-03-01

    Full Text Available OBJETIVOS: Estimar o consumo de "açúcar de adição" pela população brasileira, nos estratos regionais e socioeconômicos, destacando suas principais fontes alimentares e verificar a tendência do seu consumo nas últimas décadas. MÉTODOS: Contou-se com informações das Pesquisas de Orçamentos Familiares a partir da década de 80 sobre o tipo e a quantidade de alimentos e bebidas adquiridos pelas famílias brasileiras. Os indicadores analisados foram: % das calorias de açúcar no total calórico da dieta e % calórico das frações de açúcar de mesa e de açúcar adicionado aos alimentos pela indústria/kcal açúcar da dieta. RESULTADOS: Em 2002/03, 16,7% das calorias totais eram provenientes de "açúcar de adição" e sua participação mostrou-se elevada em todos os estratos regionais e de renda. A razão açúcar de mesa/açúcar adicionado pela indústria se inverte com o aumento da renda. A participação do açúcar de mesa nos últimos 15 anos foi reduzida, enquanto a contribuição do açúcar adicionado aos alimentos dobrou, especialmente por meio do consumo de refrigerantes e biscoitos. CONCLUSÕES: O consumo de açúcar no Brasil excede largamente a recomendação da OMS e verificou-se importante alteração nas fontes de consumo.OBJECTIVE: To describe the regional and socio-economic distribution of consumption of added sugar in Brazil in 2002/03, particularly products, sources of sugar and trends in the past 15 years. METHODS: The study used data from Household Budget Surveys since the 1980s about the type and quantity of food and beverages bought by Brazilian families. Different indicators were analyzed: % of sugar calories over the total diet energy and caloric % of table sugar fractions and sugar added to processed food/ sugar calories of diet. RESULTS: In 2002/03, of the total energy available for consumption, 16.7% came from added sugar in all regional and socio-economic strata. The table sugar/ sugar added to

  15. Tumores ósseos benignos e lesões ósseas Pseudotumorais: tratamento atual e novas tendências Benign bone tumors and tumor-like bone lesions: treatment update and new trends

    Directory of Open Access Journals (Sweden)

    José Marcos Nogueira Drumond

    2009-10-01

    Full Text Available O tratamento dos tumores ósseos benignos (TOB e lesões ósseas pseudotumorais (LOP tem visto surgir novos medicamentos, como os bisfosfonatos de uso intravenoso, que têm mostrado bons resultados no controle das lesões da displasia fibrosa. O cisto ósseo aneurismático tem sido tratado com agentes esclerosantes com sucesso. Tratamentos adjuvantes permitem a realização de cirurgias que preservam a articulação e a função, com baixas taxas de recidiva. Têm sido mais utilizados o cimento ósseo (PMMA, o fenol, a crioterapia com nitrogênio líquido, a água oxigenada, o álcool etílico e a radioterapia. Entre os novos métodos de tratamento surgidos destaca-se a ablação térmica por radiofrequência e por laser, utilizada principalmente para tratamento do osteoma osteoide. A artroscopia permite a ressecção de lesões benignas intra-articulares e assiste na ressecção de tumores subcondrais. Um grande avanço foi a utilização de substitutos sintéticos do osso, que associam substâncias osteoindutivas com material osteocondutivo e têm apresentado resultados comparáveis aos do enxerto ósseo autógeno. Há uma tendência atual para tratamentos fechados, fazendo-se a injeção percutânea de matriz óssea desmineralizada (DBM associada com sulfato de cálcio. O enxerto ósseo esponjoso autógeno permanece como o padrão ouro. O enxerto de fíbula vascularizado apresenta os melhores resultados para incorporação em lesões maiores e agressivas. Também o suporte cortical alogênico provê resistência estrutural aumentada nessas lesões mais agressivas. O aloenxerto liofilizado tem indicação para preencher defeitos contidos e para reforço do enxerto autógeno. As endopróteses articulares são utilizadas em grandes lesões destrutivas no fêmur distal, no quadril e no ombro.The treatment of benign bone tumors (BBT and tumor-like bone lesions (TBL has observed the introduction of new drugs, such as intravenous bisphosphonates

  16. Mortalidade por neoplasias no Brasil (1980/1983/1985: agrupamento dos Estados, comportamento e tendências Mortality from neoplasms in Brazil (1980/1983/1985: grouping by State, behaviors and tendencies

    Directory of Open Access Journals (Sweden)

    Fábio Gonçalves Pinto

    1991-08-01

    Full Text Available Examinou-se a mortalidade por neoplasias no Brasil, utilizando-se dados oficiais do Ministério da Saúde, abrangendo 26 Unidades da Federação e 13 diferentes localizações neoplásicas, para os anos de 1980, 1983 e 1985. As Análises de Agrupamento e de Componentes Principais revelaram comportamento heterogêneo entre regiões do país, com relação às 13 variáveis estudadas, sendo que os principais elementos discriminantes foram as neoplasias malignas da traquéia/brônquio/pulmão, seguidas das do estômago, esôfago, cólon e pâncreas. Análises complementares evidenciaram tendência de crescimento das taxas de mortalidade para as neoplasias malignas da próstata (17,74%, da traquéia/brônquio/pulmão(15,22%, da mama (11,32%, do pâncreas (10,23%, do cólon (8,08%, do colo uterino (6,45% e da laringe (6,36%. Houve redução da mortalidade por neoplasias benignas/carcinoma "in situ"/ outras (27,37%, por neoplasias malignas no reto sigmóide/ânus (7,67%, do estômago (5,31%, de outro local do útero não especificado (2,56%, por leucemia (0,70% e por neoplasias malignas do esôfago (0,44%. As neoplasias malignas do estômago foram a principal causa de morte por câncer no Brasil, representando 21,30% do total médio, seguidas das neoplasias malignas da traquéia/brônquio/pulmão(17,49% do total médio. Destacam-se os altos índices de mortalidade por neoplasias malignas do esôfago no Estado do Rio Grande do Sul.Mortality caused by neoplasms in Brazil was examined by means of official Ministry of Health data covering 26 of the Federal Units and 13 different tumoral sites and referring to the years 1980,1983 and 1985. Both cluster analyses and those of principal components have shown heterogenous behaviour as between the different regions of the country in relation to the 13 variants studied. The main discriminatory elements are the trachea/bronchus/lung malign neoplasms followed by those of stomach, pancreas, colon and larynx

  17. Extreme temperature trends in the equatorial region of Brazil: Case study of the state of Ceará Tendência das temperaturas extremas em região equatorial brasileira: estudo de caso do estado do Ceará

    Directory of Open Access Journals (Sweden)

    Eunice Maia de Andrade

    2012-06-01

    temperatura foram estimadas pelos coeficientes angulares das linhas de melhor ajuste. Os resultados mostraram que, embora haja diferenças nas tendências entre as estações, ocorreu um aumento sistemático da temperatura máxima e mínima, que foi especialmente evidente na década seguinte, dos anos 90. As maiores taxas de crescimento foram registradas para as temperaturas mínimas (de 9,0 a 8,3 °C por século para as estações de Guaramiranga e Crateús, respectivamente. Estes dados fornecem evidências para a maior retenção de energia na forma de calor sensível durante a noite possivelmente devido a uma troca de energia mais difícil, entre a superfície e a atmosfera.

  18. Mortalidade infantil em duas coortes de base populacional no Sul do Brasil: tendências e diferenciais Infant mortality in two population-based cohorts in southern Brazil: trends and differentials

    Directory of Open Access Journals (Sweden)

    Ana M. B. Menezes

    1996-01-01

    Full Text Available Estudou-se a tendência temporal da mortalidade infantil através de dois estudos de coorte realizados em Pelotas, Rio Grande do Sul, em 1982 e 1993. Ambas coortes incluíram todos os nascimentos hospitalares e óbitos verificados através de visitas regulares aos hospitais, cartórios e cemitérios. As informações sobre a causa de morte foram obtidas através de entrevistas com pediatras, revisão do prontuário, necrópsias e entrevista com os pais das crianças. O coeficiente de mortalidade infantil caiu de 36,4 por mil nascidos vivos para 21,1 na década. As principais causas de mortalidade infantil em 1993 foram as perinatais, malformações congênitas, diarréia e infecções respiratórias. Crianças com baixo peso ao nascer apresentaram mortalidade 12 vezes maior do que crianças com peso adequado, e crianças pré-termo, duas vezes mais do que crianças com retardo de crescimento intra-uterino. Crianças de famílias com renda baixa (um salário mínimo apresentaram mortalidade sete vezes superior àquelas com renda alta (10 salários mínimos. A mortalidade de crianças de baixo peso ao nascer e alta renda familiar decresceu em 67%, contra apenas 36% para as de baixa renda. Conclui-se que, mesmo com uma queda expressiva da mortalidade infantil na década, persistem importantes desigualdades sociais.Time trends in infant mortality were assessed through two cohort studies carried out in Pelotas, Southern Brazil, in 1982 and 1993. Both cohorts included all hospital deliveries, and deaths were monitored through regular visits to hospitals, cemeteries, and notary publics. Information on cause of death was obtained from pediatricians, case notes, autopsies, and home visits to parents. The infant mortality rate fell from 36.4 in 1982 to 21.1 per thousand live births in 1993. The main causes of death in 1993 were perinatal, congenital malformations, diarrhea, and respiratory infections. Low birthweight babies were twelve times more likely

  19. Pollution trends using bark of morus alba in the cities of buenos aires and mendoza (Argentina Tendências de poluição usando cascas de morus alba nas cidades de buenos aires e mendoza (Argentina

    Directory of Open Access Journals (Sweden)

    Patricia Perelman

    2010-06-01

    mostraram que Al, Fe, Mg e a acumulação de outros elementos indicaram que as partículas do solo foram espalhadas pelo vento. Na área metropolitana de Buenos Aires, o Ba e o Zn apresentaram as mais altas concentrações, possivelmente por causa do intenso tráfego automotor. O trabalho atual é uma contribuição preliminar, usando-se as árvores de Morus alba como um método indireto para estimar as tendências da poluição.

  20. Tendências de índices de extremos climáticos para a região de Manaus-AM Trends of extreme climatic indices for Manaus - AM region

    Directory of Open Access Journals (Sweden)

    Carlos Antonio Costa dos Santos

    2012-09-01

    Full Text Available Foram estudadas tendências nos índices de extremos climáticos baseados em dados de precipitação para três estações localizadas em Manaus e na região circunvizinha para o período de 1971-2007. Baseado nos resultados obtidos pode ser observado que houve aumento da precipitação total anual sobre a região estudada. A estação localizada na zona urbana de Manaus (INMET teve aumento, com significância estatística, dos eventos de precipitação iguais ou superiores a 50 mm (R50mm, na precipitação máxima acumulada em cinco dias consecutivos (Rx5day e nos dias úmidos (R95p, indicando que Manaus poderá sofrer com o aumento das chuvas extremas. Aumento das anomalias positivas de TSM no Oceano Pacífico Equatorial leva a um aumento dos dias consecutivos secos e diminuição dos eventos extremos de chuva e da precipitação total sobre a bacia amazônica. As anomalias positivas de TSM no Oceano Atlântico Sul induz o deslocamento da ZCIT mais ao sul do Equador levando a um aumento da precipitação sobre a região de Manaus. Os resultados obtidos aqui têm potencial para possíveis previsões das características da precipitação em Manaus.Trends in the extreme climate indices based on precipitation data at three stations in and around the city of Manaus for the period 1971-2007 are studied. Based on the results obtained it can be observed that there was an increase of the annual total precipitation in the area studied. At the station located in the city of Manaus (INMET, the frequency of precipitation events with 50 mm (R50mm or more, the amount precipitation in five consecutive days (Rx5day and the number of wet days (R95p, showed an increase, with statistical significance, indicating that Manaus may suffer with the increase of the extreme rainfall events. An increase in the positive SST anomalies in the Equatorial Pacific Ocean induce an increase of the consecutive dry days and decrease of the extreme rainfall events and

  1. Tendências e tensões de sociabilidade de estudantes dos Palop em duas universidades brasileiras Tendencies and tensions in the sociability of students from African countries where Portuguese is the official language at two Brazilian universities

    Directory of Open Access Journals (Sweden)

    Kelly Silva

    2012-04-01

    Full Text Available Este trabalho discute, a partir de uma perspectiva etnográfica, tendências e tensões características da sociabilidade de estudantes africanos - vindos de países de língua oficial portuguesa - na Universidade de Brasília (UnB e na Universidade de São Paulo (USP. Abordamos os modos pelos quais eles experimentam as práticas linguísticas e pedagógicas das universidades, vivenciam as tensões raciais existentes no Brasil, atribuem sentido aos espaços urbanos nos quais são acolhidos; e analisamos seus padrões mais comuns de interação e agregação. Sugerimos que o tempo de participação no fluxo migratório, a nacionalidade de origem dos estudantes e a cidade de acolhida no Brasil são variáveis que condicionam de forma importante a sociabilidade dos estudantes. Residualmente, e de forma ainda incipiente, exploramos algumas dinâmicas de identificação entre os alunos. Alguns se apresentam como sujeitos em diáspora. Outros, contudo, chamam atenção para a necessidade de continuarem a ser reconhecidos como estrangeiros. A maioria demonstra surpresa em se ver percebido como negro ou africano, simplesmente. Os estudantes vêm para o Brasil mediante o Programa Estudante Convênio de Graduação (PEC-G, um acordo diplomático que facilita o deslocamento do aluno ao nosso país a fim de realizar seu curso de nível superior.This article discusses typical tendencies and tensions of the sociability of foreign students from African countries where Portuguese is the official language at 'Universidade de Brasilia' and at 'Universidade de São Paulo'. Our analysis is carried out through an ethnographic approach. We analyze the way students experienced the linguistic and pedagogical practices at the universities, the way they make sense the urban spaces they live as well as the Brazilian typical racial tensions and their most common patterns of integration and aggregation. The time they are involved in the migratory flow, the city they live in

  2. Development trends of the international derivatives market

    OpenAIRE

    Motorniuk, U.; Terebukh, M.; Kharchuk, V.

    2016-01-01

    The factors forming international derivatives market trends are researched in this article. The history of the formation of the global derivatives market was analyzed, in particular, events which have led to the growth of the derivatives market. Global derivatives market has revealed major changes in its trends and witnessed the gradual transformation of its structure, observed in recent years. Global derivatives market has revealed major changes in its trends and witnessed the gradual transf...

  3. Assimilation of SMOS-derived soil moisture in a fully integrated hydrological and soil-vegetation-atmosphere transfer model in Western Denmark

    DEFF Research Database (Denmark)

    Ridler, Marc-Etienne Francois; Madsen, Henrik; Stisen, Simon

    2014-01-01

    -derived soil moisture assimilation in a catchment scale model is typically restricted by two challenges: (1) passive microwave is too coarse for direct assimilation and (2) the data tend to be biased. The solution proposed in this study is to disaggregate the SMOS bias using a higher resolution land cover...... classification map that was derived from Landsat thermal images. Using known correlations between SMOS bias and vegetation type, the assimilation filter is adapted to calculate biases online, using an initial bias estimate. Real SMOS-derived soil moisture is assimilated in a precalibrated catchment model...

  4. Iron and iron derived radicals

    International Nuclear Information System (INIS)

    Borg, D.C.; Schaich, K.M.

    1987-04-01

    We have discussed some reactions of iron and iron-derived oxygen radicals that may be important in the production or treatment of tissue injury. Our conclusions challenge, to some extent, the usual lines of thought in this field of research. Insofar as they are born out by subsequent developments, the lessons they teach are two: Think fast! Think small! In other words, think of the many fast reactions that can rapidly alter the production and fate of highly reactive intermediates, and when considering the impact of competitive reactions on such species, think how they affect the microenvironment (on the molecular scale) ''seen'' by each reactive molecule. 21 refs., 3 figs., 1 tab

  5. Resorcinol derivatives from Ardisia maculosa.

    Science.gov (United States)

    Zheng, Ying; Wu, Feng-E

    2007-01-01

    Besides a series of known sterols and triterpenoids, a new resorcinol (1) and a known resorcinol (2) have been isolated from ethanol extract of Ardisia maculosa for the first time. The structures of these resorcinol derivatives were elucidated as 2-methyl-5-(Z-heptadec-8-enyl) resorcinol and 5-Z-heptadec-8-enyl) resorcinol by HRESI-MS, NMR ((1)H, (13)C, HSQC, HMBC) experiments. In our in vitro assay, compounds 1 and 2 showed no antimicrobial activities, however, compound 2 exhibited cytotoxity activity against human cancer cell line with GI(50) value of 2.14 x 10(- 4) mmol/ml.

  6. Mitochondrial proteomics of the acetic acid – induced programmed cell death response in a highly tolerant Zygosaccharomyces bailii – derived hybrid strain

    Directory of Open Access Journals (Sweden)

    Joana F Guerreiro

    2016-01-01

    Full Text Available Very high concentrations of acetic acid at low pH induce programmed cell death (PCD in both the experimental model Saccharomyces cerevisiae and in Zygosaccharomyces bailii, the latter being considered the most problematic acidic food spoilage yeast due to its remarkable intrinsic resistance to this food preservative. However, while the mechanisms underlying S. cerevisiae PCD induced by acetic acid have been previously examined, the corresponding molecular players remain largely unknown in Z. bailii. Also, the reason why acetic acid concentrations known to be necrotic for S. cerevisiae induce PCD with an apoptotic phenotype in Z. bailii remains to be elucidated. In this study, a 2-DE-based expression mitochondrial proteomic analysis was explored to obtain new insights into the mechanisms involved in PCD in the Z. bailii derived hybrid strain ISA1307. This allowed the quantitative assessment of expression of protein species derived from each of the parental strains, with special emphasis on the processes taking place in the mitochondria known to play a key role in acetic acid – induced PCD. A marked decrease in the content of proteins involved in mitochondrial metabolism, in particular, in respiratory metabolism (Cor1, Rip1, Lpd1, Lat1 and Pdb1, with a concomitant increase in the abundance of proteins involved in fermentation (Pdc1, Ald4, Dld3 was registered. Other differentially expressed identified proteins also suggest the involvement of the oxidative stress response, protein translation, amino acid and nucleotide metabolism, among other processes, in the PCD response. Overall, the results strengthen the emerging concept of the importance of metabolic regulation of yeast PCD.

  7. Drug use in college students: a 13-year trend Uso de drogas entre alumnos universitarios: tendencias en 13 años Uso de drogas entre alunos universitários: tendências em 13 anos

    Directory of Open Access Journals (Sweden)

    Gabriela Arantes Wagner

    2012-06-01

    comparaciones múltiples con corrección de Bonferroni. RESULTADOS: Hubo reducción de la frecuencia de estudiantes que relataron consumo de drogas entre 1996 y 2009. Hubo disminución del uso de inhalantes y aumento en el uso de anfetamínicos en todas las medidas evaluadas [4,6% para 8,7% en la vida, de 2,4% para 4,5% en los últimos 12 meses y de 1,9% a 3,3% en los últimos 30 días]. Los alumnos de las Ciencias Humanas relataron uso de drogas con mayor frecuencia [48,6% en la vida, 29,0% en los últimos 12 meses y 20,9% en los últimos 30 días]. CONCLUSIONES: Entre los 13 años de estudio, hubo aumento de uso en la vida de cigarro, alucinógenos, anfetaminas y tranquilizantes; así como aumento en el uso de anfetaminas en los últimos 12 meses y disminución en el uso de alcohol. Con relación a los últimos 30 días, hubo aumento en el uso de anfetaminas.OBJETIVO: Analisar a tendência do uso de drogas entre universitários entre 1996, 2001 e 2009. MÉTODOS: Estudo epidemiológico transversal com 9.974 universitários do município de São Paulo, SP, cuja amostra foi selecionada por estratificação e conglomerados. Adotou-se instrumento de pesquisa de autopreenchimento, anônimo, que caracterizou o uso de drogas por três medidas: uso na vida, nos últimos 12 meses e nos últimos 30 dias. Para comparação de frequências de uso de drogas entre as pesquisas, utilizou-se a metodologia de comparações múltiplas com correção de Bonferroni. RESULTADOS: Houve redução da frequência de estudantes que relataram consumo de drogas entre 1996 e 2009. Houve diminuição do uso de inalantes e aumento do uso de anfetamínicos em todas as medidas avaliadas [4,6% para 8,7% na vida, de 2,4% para 4,5% nos últimos 12 meses e de 1,9% a 3,3% nos últimos 30 dias]. Os alunos das Ciências Humanas relataram uso de drogas com maior frequência [48,6% na vida, 29,0% nos últimos 12 meses e 20,9% nos últimos 30 dias]. CONCLUSÕES: Entre os 13 anos de estudo, houve aumento de uso na vida

  8. Topological Derivatives in Shape Optimization

    CERN Document Server

    Novotny, Antonio André

    2013-01-01

    The topological derivative is defined as the first term (correction) of the asymptotic expansion of a given shape functional with respect to a small parameter that measures the size of singular domain perturbations, such as holes, inclusions, defects, source-terms and cracks. Over the last decade, topological asymptotic analysis has become a broad, rich and fascinating research area from both theoretical and numerical standpoints. It has applications in many different fields such as shape and topology optimization, inverse problems, imaging processing and mechanical modeling including synthesis and/or optimal design of microstructures, sensitivity analysis in fracture mechanics and damage evolution modeling. Since there is no monograph on the subject at present, the authors provide here the first account of the theory which combines classical sensitivity analysis in shape optimization with asymptotic analysis by means of compound asymptotic expansions for elliptic boundary value problems. This book is intende...

  9. Antioxidant capacity of eugenol derivatives

    Directory of Open Access Journals (Sweden)

    María E. Hidalgo

    2009-01-01

    Full Text Available Toxicity and antioxidant capacity of eugenol derivatives (E2 = 2-Methoxy-4-[1-propenylphenyl]acetate, E3 = 4-Allyl-2-methoxyphenylacetate, E4 = 4-Allyl-2-methoxy-4-nitrophenol, E5 = 5-Allyl-3-nitrobenzene-1,2-diol, E6 = 4-Allyl-2-methoxy-5-nitrophenyl acetate were evaluated in order to determine the influence of the sustituents. E2-E6 were synthesized from eugenol (E1. E1 was extracted from cloves oil, and E2-E6 were obtained through acetylation and nitration reactions. Antioxidant capacity evaluated by DPPH (1, 1-Diphenyl-2-picrylhydrazil and ORAC fluorescein demonstrated that E1 and E5 have a higher capacity and the minor toxicity evaluated by red blood cells haemolysis and the Artemia saline test. In accordance with our results, the compound's (E1-E5 use in the pharmaceutical, cosmetic and or food industries could be suggested.

  10. Cytotoxicity study of pyrazole derivatives

    Directory of Open Access Journals (Sweden)

    Nusrat Binta Ahasan

    2007-06-01

    Full Text Available Pyrazolone heterocyclic compound, 3-methyl-1-phenyl-2-pyrazoline-5-one 2(a was synthesized by condensation reaction between ethyl acetoacetate and phenyl hydrazine and was converted into their corresponding heterocyclic derivatives 2(b to 2(f2 . Their cytotoxicity effects were measured by brine shrimp lethality bioassay. Among them the compounds 2(b , 2(f1 , and 2(f2 were highly active according to IC50 values 19.50, 19.50 and 20 ppm respectively. The rest of compounds 2(a , 2(c , 2(d1 , and 2(d2 having IC50 values 38, 33.50, 37.50, 36, 37.50 and 36 ppm in that order, were moderately active.

  11. Cytotoxicity study of pyrazole derivatives

    Directory of Open Access Journals (Sweden)

    Nusrat Binta Ahasan and Md. Rabiul Islam

    2007-12-01

    Full Text Available Pyrazolone heterocyclic compound, 3-methyl-1-phenyl-2-pyrazoline-5-one 2(a was synthesized by condensation reaction between ethyl acetoacetate and phenyl hydrazine and was converted into their corresponding heterocyclic derivatives 2(b to 2(f2. Their cytotoxicity effects were measured by brine shrimp lethality bioassay. Among them the compounds 2(b, 2(f1, and 2(f2 were highly active according to IC50 values 19.50, 19.50 and 20 ppm respectively. The rest of compounds 2(a, 2(c, 2(d1, and 2(d2 having IC50 values 38, 33.50, 37.50, 36, 37.50 and 36 ppm in that order, were moderately active.

  12. Silsesquioxane-derived ceramic fibres

    Science.gov (United States)

    Hurwitz, F. I.; Farmer, S. C.; Terepka, F. M.; Leonhardt, T. A.

    1991-01-01

    Fibers formed from blends of silsesquioxane polymers were characterized to study the pyrolytic conversion of these precursors to ceramics. The morphology of fibers pyrolyzed to 1400 C revealed primarily amorphous glasses whose conversion to beta-SiC is a function of both blend composition and pyrolysis conditions. Formation of beta-SiC crystallites within the glassy phase is favored by higher than stoichiometric C/Si ratios, while carbothermal reduction of Si-O bonds to form SiC with loss of SiO and CO occurs at higher methyl/phenylpropyl silsesquioxane (lower C/Si) ratios. As the carbothermal reduction is assumed to be diffusion controlled, the fibers can serve as model systems to gain understanding of the silsesquioxane pyrolysis behavior, and therefore are useful in the development of polysilsesquioxane-derived ceramic matrices and coatings as well.

  13. Radiation processing of polysaccharide derivatives

    International Nuclear Information System (INIS)

    Yoshii, Fumio

    2004-01-01

    Carboxymethylcellulose (CMC), carboxymethylstarch (CMS), carboxymethylchitin (CM-chitin) and carboxymethylchitosan (CM-chitosan) form gels when irradiated at paste-like condition. Bedsore prevention mat filled up CMC hydrogel crosslinked by irradiation at paste-like condition was practical applied as a health care products. It was found that CM-chitosan hydrogels have anti-microbial activity and effective as absorbents to remove metal ions. When crosslinked gel sheets of CM-chitin and CM-chitosan were immersed in copper (II) aqueous solution, absorption of Cu (II) were 161 mg/g and 172 mg/g, respectively. Radiation crosslinking of cellulose derivative such as hydroxypropyl methylcellulose phthalate, (HPMCP) kneaded with aqueous alkali solution and methanol was achieved with EB-irradiation at paste-like condition. The HPMCP gel absorbed organic solvents such as chloroform and pyridine. (author)

  14. Derived limits for surface contamination

    CERN Document Server

    Wrixon, A D; Linsley, G S; White, D F

    1979-01-01

    Derived limits (DLs) for surface contamination were first established for use in the nuclear energy industry where a wide variety of radionuclides is encountered. They were later used in factories, hospitals, and universities, where the radionuclides used are normally fewer in number, either known or readily identifiable, and often of low toxicity. In these situations the current limits are frequently over-restrictive. This report describes a reassessment of the values in the light of more recent information on the possible pathways of exposure and the dose equivalent limits given in ICRP Publication 26. The reassessment is prompted also by the introduction of SI units. The results of the reassessment are used to produce a classification of DLs for all radionuclides for active and inactive area surfaces and for skin.

  15. Derivation of the dipole map

    International Nuclear Information System (INIS)

    Ali, Halima; Punjabi, Alkesh; Boozer, Allen

    2004-01-01

    In our method of maps [Punjabi et al., Phy. Rev. Lett. 69, 3322 (1992), and Punjabi et al., J. Plasma Phys. 52, 91 (1994)], symplectic maps are used to calculate the trajectories of magnetic field lines in divertor tokamaks. Effects of the magnetic perturbations are calculated using the low MN map [Ali et al., Phys. Plasmas 11, 1908 (2004)] and the dipole map [Punjabi et al., Phys. Plasmas 10, 3992 (2003)]. The dipole map is used to calculate the effects of externally located current carrying coils on the trajectories of the field lines, the stochastic layer, the magnetic footprint, and the heat load distribution on the collector plates in divertor tokamaks [Punjabi et al., Phys. Plasmas 10, 3992 (2003)]. Symplectic maps are general, efficient, and preserve and respect the Hamiltonian nature of the dynamics. In this brief communication, a rigorous mathematical derivation of the dipole map is given

  16. Landslide in claystone derived soil

    Energy Technology Data Exchange (ETDEWEB)

    Richardson, A M

    1979-07-01

    This article describes a landslide that occured in the Pittsburgh area in a soil deposit derived from the Pittsburgh Redbed Claystone when a cut was made at the toe. (The Pittsburgh Redbed Claystone is the parent of much of the soil material involved in the Pittsburgh area and occurs about mid way between the base of Pittsburgh Coal and the top of the Upper Freepost Coal). The topography before the slide was known and the geometry of the slide mass was established. Slope stability analysis indicated that the landslide could have been predicted using effective stress-shear-strength parameters of s of 12 to 13 and c is 0, where s is angle of shearing resistance and c is cohesion intercept in terms of effective stresses.

  17. THE SPECIFICITY OF KERATEINE DERIVATIVES.

    Science.gov (United States)

    Pillemer, L; Ecker, E E; Martiensen, E W

    1939-09-30

    Carboxymethyl, alpha-carboxyethyl-, alpha-carboxy-n-propyl-, alpha-carboxyisopropyl-, alpha-carboxy-n-butyl, alpha-carboxyisobutyl, alpha-carboxyamyl-, benzyl-, and beta-phenylethylkeratemes were prepared from the parent protein, reduced keratin or kerateine. Chemical analysis disclosed that the various compounds differed in their isoelectric points and solubilities depending on the nature of the substituent group introduced. In general, it was found that in so far as could be determined, nearly all of the available sulfhydryl groups were substituted, while no detectable substitution of the free amino groups of the proteins occurred. The results of the serologic studies revealed that the kerateine derivatives acquired a new immunologie character dependent on the nature of the introduced determinant group. Inhibition tests confirmed the results obtained. Evidence was also produced to show that the grouping See PDF for structure may play a rôle in some of the reactions observed.

  18. Penetratin and derivatives acting as antifungal agents

    NARCIS (Netherlands)

    Masman, Marcelo F.; Rodriguez, Ana M.; Raimondi, Marcela; Zacchino, Susana A.; Luiten, Paul G. M.; Somlai, Csaba; Kortvelyesi, Tamas; Penke, Botond; Enriz, Ricardo D.

    The synthesis, in vitro evaluation, and conformational study of RQIKTWFQNRRMKWKK-NH(2) (penetratin) and related derivatives acting as antifungal agents are reported. Penetratin and some of its derivatives displayed antifungal activity against the human opportunistic pathogenic standardized ATCC

  19. Nature of the basic financial derivatives

    OpenAIRE

    Kats, Svetlana

    2014-01-01

    The article reveals the essence of basic derivatives. Studied by various authors approaches to defining derivatives and their definitions in the legislation and proposed his own definition of the most appropriate for use in accounting practice.

  20. fq-Derivations of G-Algebra

    Directory of Open Access Journals (Sweden)

    Deena Al-Kadi

    2016-01-01

    Full Text Available We introduce the notion of fq-derivation as a new derivation of G-algebra. For an endomorphism map f of any G-algebra X, we show that at least one fq-derivation of X exists. Moreover, for such a map, we show that a self-map dqf of X is fq-derivation of X if X is an associative medial G-algebra. For a medial G-algebra X, dqf is fq-derivation of X if dqf is an outside fq-derivation of X. Finally, we show that if f is the identity endomorphism of X then the composition of two fq-derivations of X is a fq-derivation. Moreover, we give a condition to get a commutative composition.

  1. Polymer-Derived Ceramic Fibers

    Science.gov (United States)

    Ichikawa, Hiroshi

    2016-07-01

    SiC-based ceramic fibers are derived from polycarbosilane or polymetallocarbosilane precursors and are classified into three groups according to their chemical composition, oxygen content, and C/Si atomic ratio. The first-generation fibers are Si-C-O (Nicalon) fibers and Si-Ti-C-O (Tyranno Lox M) fibers. Both fibers contain more than 10-wt% oxygen owing to oxidation during curing and lead to degradation in strength at temperatures exceeding 1,300°C. The maximum use temperature is 1,100°C. The second-generation fibers are SiC (Hi-Nicalon) fibers and Si-Zr-C-O (Tyranno ZMI) fibers. The oxygen content of these fibers is reduced to less than 1 wt% by electron beam irradiation curing in He. The thermal stability of these fibers is improved (they are stable up to 1,500°C), but their creep resistance is limited to a maximum of 1,150°C because their C/Si atomic ratio results in excess carbon. The third-generation fibers are stoichiometric SiC fibers, i.e., Hi-Nicalon Type S (hereafter Type S), Tyranno SA, and Sylramic™ fibers. They exhibit improved thermal stability and creep resistance up to 1,400°C. Stoichiometric SiC fibers meet many of the requirements for the use of ceramic matrix composites for high-temperature structural application. SiBN3C fibers derived from polyborosilazane also show promise for structural applications, remain in the amorphous state up to 1,800°C, and have good high-temperature creep resistance.

  2. 40 CFR 721.1820 - Bisphenol derivative.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Bisphenol derivative. 721.1820 Section... Substances § 721.1820 Bisphenol derivative. (a) Chemical substance and significant new uses subject to reporting. (1) The chemical substance identified generically as bisphenol derivative (PMN No. P-92-509) is...

  3. 45 CFR 601.5 - Derivative classification.

    Science.gov (United States)

    2010-10-01

    ... CLASSIFICATION AND DECLASSIFICATION OF NATIONAL SECURITY INFORMATION § 601.5 Derivative classification. Distinct... 45 Public Welfare 3 2010-10-01 2010-10-01 false Derivative classification. 601.5 Section 601.5... classification guide, need not possess original classification authority. (a) If a person who applies derivative...

  4. 5 CFR 1312.7 - Derivative classification.

    Science.gov (United States)

    2010-01-01

    ..., DOWNGRADING, DECLASSIFICATION AND SAFEGUARDING OF NATIONAL SECURITY INFORMATION Classification and Declassification of National Security Information § 1312.7 Derivative classification. A derivative classification... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Derivative classification. 1312.7 Section...

  5. 6 CFR 7.26 - Derivative classification.

    Science.gov (United States)

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Derivative classification. 7.26 Section 7.26 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY CLASSIFIED NATIONAL SECURITY INFORMATION Classified Information § 7.26 Derivative classification. (a) Derivative classification is defined...

  6. 22 CFR 9.6 - Derivative classification.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Derivative classification. 9.6 Section 9.6 Foreign Relations DEPARTMENT OF STATE GENERAL SECURITY INFORMATION REGULATIONS § 9.6 Derivative classification. (a) Definition. Derivative classification is the incorporating, paraphrasing, restating or...

  7. Quantum derivatives and the Schroedinger equation

    International Nuclear Information System (INIS)

    Ben Adda, Faycal; Cresson, Jacky

    2004-01-01

    We define a scale derivative for non-differentiable functions. It is constructed via quantum derivatives which take into account non-differentiability and the existence of a minimal resolution for mean representation. This justify heuristic computations made by Nottale in scale-relativity. In particular, the Schroedinger equation is derived via the scale-relativity principle and Newton's fundamental equation of dynamics

  8. 12 CFR 563.172 - Financial derivatives.

    Science.gov (United States)

    2010-01-01

    ... underlying assets, indices, or reference rates. The most common types of financial derivatives are futures, forward commitments, options, and swaps. A mortgage derivative security, such as a collateralized mortgage... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Financial derivatives. 563.172 Section 563.172...

  9. Global Distribution of Planetary Boundary Layer Height Derived from CALIPSO

    Science.gov (United States)

    Huang, J.

    2015-12-01

    The global distribution of planetary boundary layer (PBL) height, which was estimated from the attenuated back-scatter observations of Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observation (CALIPSO), is presented. In general, the PBL is capped by a temperature inversion that tends to trap moisture and aerosols. The gradient of back-scatter observed by lidar is almost always associated with this temperature inversion and the simultaneous decrease of moisture content. Thus, the PBL top is defined as the location of the maximum aerosol scattering gradient, which is analogous to the more conventional thermodynamic definition. The maximum standard deviation method, developed by Jordan et al. (2010), is modified and used to derive the global PBL heights. The derived PBL heights are not only consistent with the results of McGrath-Spangler and Denning (2012) but also agree well with the ground-based lidar measurements. It is found that the correlation between CALIPSO and the ground-based lidar was 0.73. The seasonal mean patterns from 4-year mid-day PBL heights over global are demonstrated. Also it is found that the largest PBL heights occur over the Tibetan Plateau and the coastal areas. The smallest PBL heights appear in the Tarim Basin and the northeast of China during the local winter. The comparison of PBL heights from CALIPSO and ECMWF under different land-cover conditions showed that, over ocean and forest surface, the PBL height estimated from the CALIPSO back-scatter climatology is larger than the ones estimated from ECMWF data. However, the PBL heights from ECMWF, over grass land and bare land surface in spring and summer are larger than the ones from CALIPSO.

  10. Myeloid-derived suppressor cells in breast cancer.

    Science.gov (United States)

    Markowitz, Joseph; Wesolowski, Robert; Papenfuss, Tracey; Brooks, Taylor R; Carson, William E

    2013-07-01

    Myeloid-derived suppressor cells (MDSCs) are a population of immature myeloid cells defined by their suppressive actions on immune cells such as T cells, dendritic cells, and natural killer cells. MDSCs typically are positive for the markers CD33 and CD11b but express low levels of HLADR in humans. In mice, MDSCs are typically positive for both CD11b and Gr1. These cells exert their suppressive activity on the immune system via the production of reactive oxygen species, arginase, and cytokines. These factors subsequently inhibit the activity of multiple protein targets such as the T cell receptor, STAT1, and indoleamine-pyrrole 2,3-dioxygenase. The numbers of MDSCs tend to increase with cancer burden while inhibiting MDSCs improves disease outcome in murine models. MDSCs also inhibit immune cancer therapeutics. In light of the poor prognosis of metastatic breast cancer in women and the correlation of increasing levels of MDSCs with increasing disease burden, the purposes of this review are to (1) discuss why MDSCs may be important in breast cancer, (2) describe model systems used to study MDSCs in vitro and in vivo, (3) discuss mechanisms involved in MDSC induction/function in breast cancer, and (4) present pre-clinical and clinical studies that explore modulation of the MDSC-immune system interaction in breast cancer. MDSCs inhibit the host immune response in breast cancer patients and diminishing MDSC actions may improve therapeutic outcomes.

  11. Deriving the bond pricing equation

    Directory of Open Access Journals (Sweden)

    Kožul Nataša

    2014-01-01

    Full Text Available Given the recent focus on Eurozone debt crisis and the credit rating downgrade not only of US debt, but that of other countries and many UK major banking institutions, this paper aims to explain the concept of bond yield, its different measures and bond pricing equation. Yields on capital market instruments are rarely quoted on the same basis, which makes direct comparison between different as investment choices impossible. Some debt instruments are quoted on discount basis, whilst coupon-bearing ones accrue interest differently, offer different compounding opportunities, have different coupon payment frequencies, and manage non-business day maturity dates differently. Moreover, rules governing debt vary across countries, markets and currencies, making yield calculation and comparison a rather complex issue. Thus, some fundamental concepts applicable to debt instrument yield measurement, with focus on bond equation, are presented here. In addition, bond equation expressed in annuity form and used to apply Newton-Raphson algorithm to derive true bond yield is also shown.

  12. Classical gravity with higher derivatives

    International Nuclear Information System (INIS)

    Stelle, K.S.

    1978-01-01

    Inclusion of the four-derivative terms ∫Rsub(μν) Rsup(μν)(-g)sup(1/2) and ∫R 2 (-g)sup(1/2) into the gravitational action gives a class of effectively multimass models of gravity. In addition to the usual massless excitations of the field, there are now, for general amounts of the two new terms, massive spin-two and massive scalar excitations, with a total of eight degrees of freedom. The massive spin-two part of the field has negative energy. Specific ration of the two new terms give models with either the massive tensor or the massive scalar missing, with correspondingly fewer degrees of freedom. The static, linearized solutions of the field equations are combinations of Newtonian and Yukawa potentials. Owing to the Yukawa form of the corrections, observational evidence sets only very weak restrictions on the new masses. The acceptable static metric solutions in the full nonlinear theory are regular at the origin. The dynamical content of the linearized field is analyzed by reducing the fourth-order field equations to separated second-order equations, related by coupling to external sources in a fixed ratio. This analysis is carried out into the various helicity components using the transverse-traceless decomposition of the metric. (author)

  13. The estimation of derived limits

    International Nuclear Information System (INIS)

    Harrison, N.T.; Bryant, P.M.; Clarke, R.H.; Morley, F.

    1979-08-01

    In practical radiation protection, it is often necessary to calculate limits of intake of radionuclides associated with various quantities; such limits are needed, for example, to assess the adequacy of the control of environmental contamination. In publication 26 of the International Commission on Radiological Protection (ICRP), these limits, when related to the basic limits of dose-equivalent by a defined model, are referred to as Derived Limits (DLs). In the present report the principles to be adopted by the Board in calculating DLs to be recommended for general application within the United Kingdom are outlined. DLs will be recommended for a wide range of radionuclides and for circumstances relevant to the workplace, and, more frequently, the general environment. The latter will include DLs in foodstuffs and associated environmental materials, such as soil and grass, and DLs for discharges from stacks. DLs will be related to dose equivalents for workers or members of the public for stochastic or non-stochastic effects as appropriate. Consideration will be given to relevant data on radiosensitivity, metabolism and dosimetry for children and to the physicochemical forms of radionuclides. (author)

  14. Option Derivatives in Electricity Hedging

    Directory of Open Access Journals (Sweden)

    P. Pavlátka

    2010-01-01

    Full Text Available Despite the high volatility of electricity prices, there is still little demand for electricity power options, and the liquidity on the power exchanges of these power derivatives is quite low. One of the reasons is the uncertainty about how to evaluate these electricity options and about finding the right fair value of this product. Hedging of electricity is associated mainly with products such as futures and forwards. However, due to new trends in electricity trading and hedging, it is also useful to think more about options and the principles for working with them in hedging various portfolio positions and counterparties. We can quite often encounter a situation when we need to have a perfect hedge for our customer’s (end user consuming electricity portfolio, or we have to evaluate the volumetric risk (inability of a customer to predict consumption, which is very similar to selling options. Now comes the moment to compare the effects of using options or futures to hedge these open positions. From a practical viewpoint, the Black-Scholes prices appear to be the best available and the simplest method for evaluating option premiums, but there are some limitations that we have to consider.

  15. The Combined Effects of Financial Derivatives and Discretionary Accruals on the Value Relevance of Earnings and the Book Value of Equity

    Directory of Open Access Journals (Sweden)

    Etty Murwaningsari

    2015-08-01

    Full Text Available This study aimed to understand (1 the association between the use of discretionary accruals and financial derivatives, taking into consideration the implementation of revised PSAK 55 (1999, which was adopted from SFAS 133; (2 the combined effects of derivatives and discretionary accruals on the value relevance of earnings and equity. The analysis used panel data regressions and the Wald test over the period from 2001-2008. The results showed a positive or complementary association between derivatives and discretionary accruals. The positive association implied that managers tended to intensify the use of discretionary accruals to offset a higher use of derivatives. Price and return models demonstrated negative significant effects of derivatives on the value relevance of earnings. The return model showed negative significant effects of discretionary accruals on the value relevance of earnings but negative effects on the value relevance of equity with the price model.

  16. 21 CFR 184.1685 - Rennet (animal-derived) and chymosin preparation (fermentation-derived).

    Science.gov (United States)

    2010-04-01

    ... (fermentation-derived). 184.1685 Section 184.1685 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF... (animal-derived) and chymosin preparation (fermentation-derived). (a)(1) Rennet and bovine rennet are... clear solution containing the active enzyme chymosin (E.C. 3.4.23.4). It is derived, via fermentation...

  17. Efeito da localização do nó de sutura na recuperação morfofuncional do tendão flexor digital profundo do membro torácico do cão após tenorrafia experimental

    Directory of Open Access Journals (Sweden)

    Julieta Rodini Engrácia de Moraes

    2000-01-01

    Full Text Available Este estudo teve por escopo comparar a influência do nó de sutura em três diferentes localizações na recuperação morfofuncional do tendão flexor digital profundo (TFDP do cão. Foram utilizados 20 cães divididos em três grupos de oito, sete e cinco animais. Os TFDP do segundo e quinto dedos do membro torácico esquerdo foram seccionados e suturados pela técnica de Kessler modificada, alterando-se a localização do nó e o tipo de sutura no epitendíneo. No grupo um, o nó da sutura ficou localizado na região ventral do tendão e no grupo dois na face dorsal. Em ambos os grupos, o epitendão foi suturado com pontos simples separados. No grupo três, o nó da sutura ficou interno ao endotendíneo e o epitendíneo foi suturado com ponto simples contínuo. Após a cirurgia, foi realizada diariamente a movimentação passiva controlada do membro do primeiro ao 15º dia. No 7º e no 15º dia os animais foram sacrificados por anestesia profunda e os tendões foram colhidos para avaliação macroscópica do processo de reparo tendíneo. O critério de comparação utilizou como parâmetros para avaliar a recuperação morfofuncional a ruptura do tendão, o afastamento dos cotos e a coaptação completa dos cotos tendíneos. O grupo que apresentou melhor resultado com relação aos parâmetros avaliados foi o terceiro, com ausência de ruptura e índice de afastamento de apenas 2,5% dos cotos tendíneos. Os resultados encontrados permitem concluir que a localização do nó de sutura na tenorrafia do TFDP interfere na resposta reparadora e biomecânica.

  18. Tendências da mortalidade neonatal em São Luís, Maranhão, Brasil, de 1979 a 1996 Neonatal mortality trends in São Luís, Maranhão, Brazil, from 1979 to 1996

    Directory of Open Access Journals (Sweden)

    Valdinar Sousa Ribeiro

    2000-06-01

    Full Text Available O propósito do presente trabalho é avaliar a evolução da mortalidade neonatal em São Luís nos últimos 18 anos, classificá-la de acordo com os dias de vida e pelo critério de evitabilidade de óbitos da Fundação SEADE, a partir de dados do IBGE e do Ministério da Saúde. Detectou-se aumento da mortalidade neonatal, às custas de aumento expressivo do seu componente precoce, especialmente pelas causas reduzíveis por diagnóstico e tratamento precoce, e parcialmente reduzíveis por adequado controle da gravidez. A mortalidade infantil, desse modo, manteve-se inalterada, apesar do decréscimo do seu componente pós-neonatal. O aumento expressivo no coeficiente de mortalidade neonatal a partir de 1995 aponta para a queda na qualidade da assistência obstétrica e neonatal, talvez motivada pelo elevado percentual de cesáreas e pela superlotação dos berçários. A tendência de estabilidade ou aumento da mortalidade neonatal é semelhante à observada recentemente no Brasil como um todo e difere da observada em outras cidades brasileiras, nas quais foi descrita queda lenta, mas persistente, da mortalidade neonatal, em oposição a uma redução mais dramática em países desenvolvidos.This study examined neonatal mortality trends in São Luís in the last 18 years. The early and late components were assessed and causes were classified according to SEADE Foundation criteria based on reducibility of deaths and timing of prevention (during prenatal care, childbirth, or neonatal care. Data were derived from official live birth and death records. We detected an unexpected increase in the neonatal mortality rate, due primarily to a steep rise in early neonatal deaths. Causes reducible by early diagnosis and treatment (other specific infections and other neonatal respiratory causes and those partially reducible by adequate monitoring of pregnancy (preterm births, low birth weight, and respiratory distress syndrome showed the largest increase

  19. Estimativas de parâmetros genéticos e de tendência fenotípica, genética e de ambiente de algumas características reprodutivas na raça Gir Estimates of genetic parameters and phenotypic, genetic and environmental trends of some reproductive traits in Gir cattle

    Directory of Open Access Journals (Sweden)

    E.S. Balieiro

    1999-08-01

    Full Text Available O objetivo do estudo foi estimar os parâmetros e as tendências fenotípica, genética e ambiental para idade ao primeiro parto (IPP e intervalo de partos (IDP na raça Gir, com o emprego de análises uni e bivariadas sob o método da máxima verossimilhança restrita, por meio de algoritmo livre de derivadas (MTDFREML, que ajusta o modelo animal. O modelo matemático adotado para estudo do IDP incluiu os efeitos fixos rebanho-ano de parto, época de parto e idade da vaca ao parto como covariável e os efeitos aleatórios de animal e ambiente permanente. Para a IPP, o modelo incluiu os efeitos fixos rebanho-ano de nascimento e época de nascimento e efeito de animal como aleatório. Por meio de análises bivariadas, as estimativas de herdabilidade foram 0,17 para IPP e 0,06 para IDP. A estimativa de repetibilidade para IDP foi 0,17. As correlações fenotípica, genética e de ambiente entre IPP e IDP foram, respectivamente, 0,06, 0,37 e 0,03. As mudanças anuais fenotípica, genética e de ambiente para IPP foram, respectivamente, -0,446±0,077 (PThe aims of the present study were to estimate genetic parameters, as well as phenotypic, genetic and environmental trends for age at first calving (AFC and calving intervals (CI on Gyr dairy breed, using a multivariate derivative-free restricted maximum likelihood (MTDFREML with an animal model. The mathematic model for calving interval included herd-year of calving, calving season, and the covariate age of cow as fixed effects, and animal, and permanent environment as random effects. The model for age at first calving included herd-year of birth and season of birth as fixed effects, and animal as random effect. Through the bivariate analyses, estimates of heritability were: for age at first calving 0.17 and for calving interval 0.06. The estimate of repeatability for calving interval was 0.17. The phenotypic, genetic and environmental correlations between age at first calving and calving interval

  20. Drug Nanoparticle Formulation Using Ascorbic Acid Derivatives

    Directory of Open Access Journals (Sweden)

    Kunikazu Moribe

    2011-01-01

    Full Text Available Drug nanoparticle formulation using ascorbic acid derivatives and its therapeutic uses have recently been introduced. Hydrophilic ascorbic acid derivatives such as ascorbyl glycoside have been used not only as antioxidants but also as food and pharmaceutical excipients. In addition to drug solubilization, drug nanoparticle formation was observed using ascorbyl glycoside. Hydrophobic ascorbic acid derivatives such as ascorbyl mono- and di-n-alkyl fatty acid derivatives are used either as drugs or carrier components. Ascorbyl n-alkyl fatty acid derivatives have been formulated as antioxidants or anticancer drugs for nanoparticle formulations such as micelles, microemulsions, and liposomes. ASC-P vesicles called aspasomes are submicron-sized particles that can encapsulate hydrophilic drugs. Several transdermal and injectable formulations of ascorbyl n-alkyl fatty acid derivatives were used, including ascorbyl palmitate.

  1. Perturbative reduction of derivative order in EFT

    Science.gov (United States)

    Glavan, Dražen

    2018-02-01

    Higher derivative corrections are ubiquitous in effective field theories, which seemingly introduces new degrees of freedom at successive orders. This is actually an artefact of the implicit local derivative expansion defining effective field theories. We argue that higher derivative corrections that introduce additional degrees of freedom should be removed and their effects captured either by lower derivative corrections, or special combinations of higher derivative corrections not propagating extra degrees of freedom. Three methods adapted for this task are examined and field redefinitions are found to be most appropriate. First order higher derivative corrections in a scalar tensor theory are removed by field redefinition and it is found that their effects are captured by a subset of Horndeski theories. A case is made for restricting the effective field theory expansions in principle to only terms not introducing additional degrees of freedom.

  2. Weather Derivatives – Origin, Types and Application

    Directory of Open Access Journals (Sweden)

    Piotr Binkowski

    2008-01-01

    Full Text Available The number of companies that are exposed to the revenues loss risk caused by weather variability is still increasing. The businesses that are mostly exposed to weather risk are following: energy, agriculture, constructions and transport. That situation has initiated dynamic growth of weather derivatives markets as well as the awareness of the weather risk among the market participants. Presently, the weather derivatives markets evaluate rapidly in all the mature economies: USA, Asia and Europe. Constructing weather derivatives relies on qu- antifying climate factors in the form of indexes, what is quite simple task, more difficultly can be gathering precise historical data of required climate factors. Taking into consideration so far development of derivatives especially the financial derivatives based on different types of indexes financial market has at disposal wide range of different types of proved derivatives (futures, forward, options, swaps, which can be successfully utilised on the weather-driven markets both for hedging weather risk and speculating.

  3. Derivative pricing based on local utility maximization

    OpenAIRE

    Jan Kallsen

    2002-01-01

    This paper discusses a new approach to contingent claim valuation in general incomplete market models. We determine the neutral derivative price which occurs if investors maximize their local utility and if derivative demand and supply are balanced. We also introduce the sensitivity process of a contingent claim. This process quantifies the reliability of the neutral derivative price and it can be used to construct price bounds. Moreover, it allows to calibrate market models in order to be co...

  4. Chromatic Derivatives, Chromatic Expansions and Associated Spaces

    OpenAIRE

    Ignjatovic, Aleksandar

    2009-01-01

    This paper presents the basic properties of chromatic derivatives and chromatic expansions and provides an appropriate motivation for introducing these notions. Chromatic derivatives are special, numerically robust linear differential operators which correspond to certain families of orthogonal polynomials. Chromatic expansions are series of the corresponding special functions, which possess the best features of both the Taylor and the Shannon expansions. This makes chromatic derivatives and ...

  5. Quantile driven identification of structural derivatives

    OpenAIRE

    Andrew Chesher

    2001-01-01

    Conditions are derived under which there is local nonparametric identification of derivatives of structural equations in nonlinear triangular simultaneous equations systems. The attack on this problem is via conditional quantile functions and exploits local quantile independence conditions. The identification conditions include local analogues of the order and rank conditions familiar in the analysis of linear simultaneous equations models. The objects whose identification is sought are deriv...

  6. Isotope-labelled folic acid derivatives

    International Nuclear Information System (INIS)

    Lewin, N.; Wong, E.T.

    1976-01-01

    The suggestion deals with the production of folic acid derivatives suitable as indicators or tracers for analyses of serum folates. These folic acid derivatives contain folic acid which is bound by one or both carboxyl groups to the amino nitrogen of compounds such as, e.g., tyramine, glycyl tyrosine, tyrosine, or the methyl ester of tyrosine. The derivative obtained can be substituted by a gamma emitter, e.g. the iodine isotope I 125. The radioactive derivative is used in the method for the competitive protein bonding to determine endogenic folates in the serum. (UWI) [de

  7. Elongamento do enxerto de tendões do músculo grácial e semitendinoso humanos: estudo realizado em cadáveres de adultos jovens Graft semitendinosus and gracilis human muscle tendons elongation: a study carried out on young adult human cadavers

    Directory of Open Access Journals (Sweden)

    Sérgio Rocha Piedade

    2005-01-01

    Full Text Available Na cirurgia de reconstrução do ligamento cruzado anterior do joelho, os enxertos de tendões autólogos são a principal opção como substitutos ligamentares. Entretanto, uma das razões da falha da reconstrução ligamentar com tecidos moles é o estiramento ou elongamento do enxerto com o tempo. Neste trabalho, foram ensaiados oito tendões do músculo grácil e oito do músculo semitendinoso humanos, obtidos de quatro cadáveres do sexo masculino, com idade média de 24,5 anos. Cada tendão foi submetido a uma deformação relativa constante de 2,5% durante 600 s, com registro contínuo do relaxamento de força. A seguir, o tendão retornava ao seu comprimento inicial e era mantido num período de repouso de 300 s. Após este intervalo, um segundo ensaio, semelhante ao primeiro, era realizado. A velocidade de carregamento empregada foi de 10% do comprimento inicial do corpo de prova por segundo. Foram obtidos valores de força inicial, com 300 s e 600 s nos dois ensaios. A análise estatística sugere um comportamento mecânico mais uniforme para o tendão do músculo semitendinoso quando comparado ao tendão do músculo grácil.In the anterior cruciate ligament knee surgery reconstruction, autologous tendons graft remains as a main option as substitutive ligaments. However time effect on graft elongation is the main reason of ligament reconstruction failure. Traction tests have been performed on eight gracilis as well as on eight semitendinosus human muscles tendons obtained from four male cadavers at an average of 24.5 years. Each tendon specimen has been submitted to a deformation of 2.5% of its initial length for a time interval of 600 s with continuous recording of the corresponding force relaxation. The tendon specimen was then kept at rest for 300 s as soon as it returned to its initial length. The same specimen was then submitted to a similar test. Deformation rate for both tests was 10% of its initial length per second. Initial

  8. Superstability for Generalized Module Left Derivations and Generalized Module Derivations on a Banach Module (I

    Directory of Open Access Journals (Sweden)

    Rassias JM

    2009-01-01

    Full Text Available We discuss the superstability of generalized module left derivations and generalized module derivations on a Banach module. Let be a Banach algebra and a Banach -module, and . The mappings , and are defined and it is proved that if (resp., is dominated by then is a generalized (resp., linear module- left derivation and is a (resp., linear module- left derivation. It is also shown that if (resp., is dominated by then is a generalized (resp., linear module- derivation and is a (resp., linear module- derivation.

  9. Comparison of in-flight and ground-based simulator derived flying qualities and pilot performance for approach and landing tasks

    Science.gov (United States)

    Grantham, William D.; Williams, Robert H.

    1987-01-01

    For the case of an approach-and-landing piloting task emphasizing response to the landing flare, pilot opinion and performance parameters derived from jet transport aircraft six-degree-of-freedom ground-based and in-flight simulators were compared in order to derive data for the flight-controls/flying-qualities engineers. The data thus obtained indicate that ground simulation results tend to be conservative, and that the effect of control sensitivity is more pronounced for ground simulation. The pilot also has a greater tendency to generate pilot-induced oscillation in ground-based simulation than in flight.

  10. Stars rich in heavy metals tend to harbor planets

    CERN Multimedia

    2003-01-01

    "A comparison of 754 nearby stars like our Sun - some with planets and some without - shows definitively that the more iron and other metals there are in a star, the greater the chance it has a companion planet" (1 page).

  11. Tendências da desigualdade educacional no Brasil

    Directory of Open Access Journals (Sweden)

    Silva Nelson do Valle

    2000-01-01

    Full Text Available Even today, Brazil's educational indicators are only slightly better than those of the poorest countries in Latin America. Nevertheless, the slow but continuous expansion in schooling in the last two decades has increased the Brazilian population's educational level and decreased inequality according to region, color, gender, and income bracket. By breaking down the explanatory factors for educational improvement, this study suggests, as a conservative estimate, that approximately 60% of this improvement is due to changes in living conditions and the geographic distribution of families resulting from urbanization and the demographic transition, with the remaining 40% due to actual improvements in the educational system's performance.

  12. Storage solutions for excavated textiles tending to their recalcitrant behaviour

    DEFF Research Database (Denmark)

    Margariti, Christina; Loukopoulou, Polytimi

    2016-01-01

    , the system selected and the materials used. The box-in-box method was selected for better controlling environmental parameters. The textiles were systematically organised in a way that they are stable and readily accessible withminimum handling. Thematerials used included open and close-cell polyethylene...

  13. State estimation of chemical engineering systems tending to multiple solutions

    Directory of Open Access Journals (Sweden)

    N. P. G. Salau

    2014-09-01

    Full Text Available A well-evaluated state covariance matrix avoids error propagation due to divergence issues and, thereby, it is crucial for a successful state estimator design. In this paper we investigate the performance of the state covariance matrices used in three unconstrained Extended Kalman Filter (EKF formulations and one constrained EKF formulation (CEKF. As benchmark case studies we have chosen: a a batch chemical reactor with reversible reactions whose system model and measurement are such that multiple states satisfy the equilibrium condition and b a CSTR with exothermic irreversible reactions and cooling jacket energy balance whose nonlinear behavior includes multiple steady-states and limit cycles. The results have shown that CEKF is in general the best choice of EKF formulations (even if they are constrained with an ad hoc clipping strategy which avoids undesired states for such case studies. Contrary to a clipped EKF formulation, CEKF incorporates constraints into an optimization problem, which minimizes the noise in a least square sense preventing a bad noise distribution. It is also shown that, although the Moving Horizon Estimation (MHE provides greater robustness to a poor guess of the initial state, converging in less steps to the actual states, it is not justified for our examples due to the high additional computational effort.

  14. Metamorfoses e tendências no xadrez do poder mundial

    Directory of Open Access Journals (Sweden)

    Paulo Duarte

    2014-07-01

    This article aims to analyse the new trends in the balance of world power, which has fragmented and diluted itself contrary to what occurred previously. In this sense, we will try to outline some scenarios marked by either a multilateralist or unilateralist posture, or even by the coexistence of both in what regards the behaviour of the USA, in order to speculate how the US hegemon can act in this new world order, characterised by various challenges and threats.

  15. Tendências no ensino da epidemiologia no Brasil

    OpenAIRE

    Barata Rita Barradas

    1997-01-01

    O ensino da epidemiologia teve início no Brasil na década de 20 e sempre foi voltado para a saúde pública. Na década de 70, o ensino de epidemiologia passou por um crescimento em nível de pós-graduação. Os anos 80 foram marcados pela "epidemiologia social", que incorporava as ciências sociais e seus métodos; a segunda metade da década foi marcada pelo desenvolvimento das técnicas da bioestatística. No momento atual, a definição de diretrizes para o ensino da epidemiologia depende da reflexão ...

  16. Tending a Virtual Garden: Exploring Connectivity between Cities

    DEFF Research Database (Denmark)

    Pakanen, Minna; Polli, Anna Maria; Lee, Stella

    2013-01-01

    their waiting time. ‘Virtual Garden’ creates the experience of ‘being connected’ by providing users with the possibility to ‘grow’ a collaborative garden using a smartphone and natural gestures as the control interaction. Lo-fi prototypes were used to gather user feedback which informed the design...... of the 'Virtual Garden'....

  17. Tending for Cattle: Traditional Fire Management in Ethiopian Montane Heathlands

    Directory of Open Access Journals (Sweden)

    Maria U. Johansson

    2012-09-01

    Full Text Available Fire has long been a principal tool for manipulating ecosystems, notably for pastoralist cultures, but in modern times, fire use has often been a source of conflicts with state bureaucracies. Despite this, traditional fire management practices have rarely been examined from a perspective of fire behavior and fire effects, which hampers dialogue on management options. In order to analyze the rationale for fire use, its practical handling, and ecological effects in high-elevation ericaceous heathlands in Ethiopia, we used three different information sources: interviews with pastoralists, field observations of fires, and analysis of vegetation age structure at the landscape level. The interviews revealed three primary reasons for burning: increasing the grazing value, controlling a toxic caterpillar, and reducing predator attacks. Informants were well aware of critical factors governing fire behavior, such as slope, wind, vertical and horizontal fuel structure, and fuel moisture. Recent burns (1-4 years since fire were used as firebreaks to control the size of individual burns, which resulted in a mosaic of vegetation of different ages. The age structure indicated an average fire return interval of ~10 years. At these elevations (> 3500 m, the dry period is unreliable, with occasional rains. Of all observed fires, 83% were ignited during very high Fire Weather Index levels, reached during only 11% of all days of the year. Burning is illegal, but if this ban was respected, our data suggest that the Erica shrubs would grow out of reach of cattle within a few years only, creating a dense and continuous canopy. This would also create a risk of large high-intensity wildfires since the landscape is virtually devoid of natural fuel breaks. Under the present management regime, this heathland ecosystem should be quite resilient to degradation by fire due to a relatively slow fuel buildup (limiting fire intervals and an effective regrowth of Erica shoots. Nevertheless, if burning is done during severe drought, there may be a risk of smoldering fires killing the lignotubers. Given the intimate knowledge of fire behavior and fire effects among these pastoralists, it should be possible to develop a fire management plan that can sustain the present land use and ecosystem, and be sanctioned by both authorities and the local community.

  18. Relationship of Services Utility with Patients Tending to Hospitals

    Directory of Open Access Journals (Sweden)

    A. A. Nasiripour

    2013-09-01

    Full Text Available Background & purpose: In the health sector, in addition to the important consequence of treatment, health system should meet the expectations regarding the desirability of services. Expectations and perceptions of patients about the desirability of services play an important role in selecting hospitals, their loyalty to the organization & replanning to purchase. Thus the present study has been done with the aim to determine the relationship between services desirability and patients’ tendency to public or private hospitals in Sari. Materials & Methods: This study is a descriptive and analytical type done in 2012 in four private and public hospitals located in Sari. The study population consists of hospitalized patients that have been subjected to inquiry by using 361stratified random samples. The survey tool was questionnaire that its validity was judged and approved by the teachers and its reliability was obtained by alpha Cronbach as 0.972. The collected data was analyzed by SPSS software, independent t-test, t-sample test and descriptive statistics. Results: Findings show that in services cost indexes, there are not any significant differences between public and private hospitals while in the other services desirability indexes such as accessibility, availability, speed, quality, and complete package of services and …, there is a significant difference between public and private hospitals. Conclusion: In patients’ tendency to hospitals, utility service indicators satisfy a significant impact. So, codified planning to improve these indexes in order to absorb more patients by authorities is required.

  19. Tendências da gestão social

    Directory of Open Access Journals (Sweden)

    Ladislau Dowbor

    1999-02-01

    Full Text Available O que está se tornando evidente, já não numa visão estreita de crítica sistemática anti-capitalista, mas de bom senso econômico e social, é que um sistema que sabe produzir, mas não sabe distribuir, simplesmente não é suficiente. Sobretudo se, ainda por cima, joga milhões no desemprego, dilapida o meio-ambiente e remunera mais os especuladores do que os produtores. E a construção de alternativas envolve um leque de alianças sociais evidentemente mais amplo do que o conceito de classes redentoras, burguesa para uns, proletária para outros, que dominou o século XX. O debate sobre quem tinha razão continuará sem dúvida a alimentar as nossas discussões, mas a realidade é que a própria realidade mudou. O crescimento econômico, quando existe, não é suficiente. Nem a área produtiva, nem as redes de infraestruturas, e nem os serviços de intermediação funcionarão de maneira adequada se não houver investimento no ser humano, na sua formação, na sua saúde, na sua cultura, no seu lazer, na sua informação. Em outros termos, a dimensão social do desenvolvimento deixa de ser um "complemento", uma dimensão humanitária de certa forma externa aos processos econômicos centrais, para se tornar um dos componentes essenciais da transformação social que vivemos. Será preciso lembrar que o principal setor econômico nos Estados Unidos, não é mais a indústria automobilística, ou bélica, mas a saúde, que representa 14% do seu PIB? A questão que se coloca, e que analisamos neste artigo, é que enquanto as áreas produtivas dispõem de um sólido acúmulo teórico sobre a sua gestão - taylorismo, fordismo, toyotismo, TQM, Kanban etc. - a área social não dispõe dos paradigmas de gestão correspondentes, e fica oscilando entre burocratismos estatais ultrapassados, e privatizações desastrosas. Os serviços sociais são diferentes e necessitam de respostas específicas. A questão da gestão social tornou-se central.Capitalism is a good system when production is concerned, but not good enough a system if we want adequate distribution. And a system that produces well, but does not distribute accordingly, is structurally unbalanced. We need alternatives. What we have had up to now are not alternatives, but simplifications, with statism on one side, and liberalism on the other, redemption being expected to come either from the bourgeoisie or from the proletariat, depending on the political views. This debate will continue, but reality has changed. Economic growth is obviously not sufficient, assuming it exists. No modern economic activity can be stimulated if we do not have the corresponding investment in people, through health, education, culture, leisure and so on. Social activities are no longer a complement to banking and industry. They have become central to the economy itself. In the U.S., the new economic locomotive is not the car industry, but health, representing 14% of GDP. While social services have become central in modern economies, they still have to find their management paradigm. Huge, centralized state burocracies are not responsive enough, while privatization has led to dramatic abuse. The lack of specific management responses to the new demands of social services has become a key problem both in avanced and developing economies.

  20. Derivative analyticity relations and asymptotic energies

    International Nuclear Information System (INIS)

    Fischer, J.

    1976-01-01

    On the basis of general principles of the S-matrix theory theorems are derived showing that derivative analyticity relations analogous to those of Bronzen, Kane and Sukhatme hold at asymptotic energies if the high-energy limits of certain physical quantities exist

  1. 28 CFR 17.26 - Derivative classification.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Derivative classification. 17.26 Section 17.26 Judicial Administration DEPARTMENT OF JUSTICE CLASSIFIED NATIONAL SECURITY INFORMATION AND ACCESS TO CLASSIFIED INFORMATION Classified Information § 17.26 Derivative classification. (a) Persons...

  2. 5 CFR 2500.5 - Derivative classification.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Derivative classification. 2500.5 Section 2500.5 Administrative Personnel OFFICE OF ADMINISTRATION, EXECUTIVE OFFICE OF THE PRESIDENT INFORMATION SECURITY REGULATION § 2500.5 Derivative classification. The Office of Administration serves only as the...

  3. Derivative Securities and Financial Crisis in Romania

    OpenAIRE

    Gogoncea Ramona

    2012-01-01

    This paper aims to investigate the impact of the global financial crisis on the young Romanian market of derivative securities. It also describes the recent developments within Romanian capital market, in general, with focus on innovation in the field of derivative products.

  4. 46 CFR 503.55 - Derivative classification.

    Science.gov (United States)

    2010-10-01

    ... Security Program § 503.55 Derivative classification. (a) In accordance with Part 2 of Executive Order 12958 and directives of the Information Security Oversight Office, the incorporation, paraphrasing... 46 Shipping 9 2010-10-01 2010-10-01 false Derivative classification. 503.55 Section 503.55...

  5. Synthesis and Cytotoxicity of Novel Hexahydrothienocycloheptapyridazinone Derivatives

    Directory of Open Access Journals (Sweden)

    Irene Marchesi

    2009-09-01

    Full Text Available Designed as a new group of tricyclic molecules containing the thienocycloheptapyridazinone ring system, a number of 2N-substituted-hexahydrothienocycloheptapyridazinone derivatives were synthesized and their biological activity evaluated. Among the synthesized compounds, derivatives 7d and 7h were found to possess cytotoxic activity against non-small cell lung cancer and central nervous system cancer cell lines, respectively.

  6. "Nonmorphological Derivations" and the Four Main English ...

    African Journals Online (AJOL)

    This article addresses the problem of "nonmorphological derivations" in English and its consequences for pedagogical lexicography, i.e. learner's dictionaries. The term "nonmorphological derivation" refers to cases such as sun — solar, moon — lunar, cat — feline, and in general to all cases where instead of, or in addition ...

  7. Mesogenic benzothiazole derivatives with methoxy substituents

    Indian Academy of Sciences (India)

    Unknown

    2003-10-11

    Oct 11, 2003 ... literature. Barbera et al14 have synthesized 2-pyr- azoline derivatives and also studied the optical,. NLO and mesogenic properties of such materials. Highly polar thiophene-based liquid crystals have also been reported15 in the literature. However, fused ring heterocyclic derivatives which are two conden-.

  8. Deriving force field parameters for coordination complexes

    DEFF Research Database (Denmark)

    Norrby, Per-Ola; Brandt, Peter

    2001-01-01

    The process of deriving molecular mechanics force fields for coordination complexes is outlined. Force field basics are introduced with an emphasis on special requirements for metal complexes. The review is then focused on how to set up the initial model, define the target, refine the parameters......, and validate the final force field, Alternatives to force field derivation are discussed briefly....

  9. Weyl and Marchaud Derivatives: A Forgotten History

    Directory of Open Access Journals (Sweden)

    Fausto Ferrari

    2018-01-01

    Full Text Available In this paper, we recall the contribution given by Hermann Weyl and André Marchaud to the notion of fractional derivative. In addition, we discuss some relationships between the fractional Laplace operator and Marchaud derivative in the perspective to generalize these objects to different fields of the mathematics.

  10. Weyl and Marchaud derivatives: a forgotten history

    OpenAIRE

    Ferrari, Fausto

    2017-01-01

    In this paper, we recall the contribution given by Hermann Weyl and André Marchaud to the notion of fractional derivative. In addition, we discuss some relationships between the fractional Laplace operator and Marchaud derivative in the perspective to generalize these objects to different fields of the mathematics.

  11. New uracil derivatives and their biological activity

    International Nuclear Information System (INIS)

    Hudecova, D.; Striganova, J.; Chovanec, P.; Uher, M.

    1998-01-01

    Present study is concentrated to the research of antimicrobial activity of some derivatives of the uracil and 1,3-dimethyluracyl. The antimicrobial effects of these compounds have been tested on various strains of bacteria, yeasts, and filamentous fungi. The highest antimicrobial effects were found with dithiocarbamato-derivatives, which were effective against pathogenic and non-pathogenic bacteria (IC 50 = 7-25 μg cm -3 ), yeasts (IC 50 = 9-60 μg cm -3 ) and filamentous fungi.The most sensitive fungus to dithiocarbamato-derivatives was Botritis cinerea. It seems to be apparent that the presence of the -NH-C(S)-S- group in molecules of derivatives of uracil and and 1,3-dimethyluracyl influencing the incorporation rate [ 14 ]-adenine and 14 ]-leucine into the biomolecules and also markedly inhibits oxygen consumption (IC 50 = 58 μg cm -3 ). The same derivative demonstrated no mutagenic activity. (authors)

  12. Generalized Fractional Derivative Anisotropic Viscoelastic Characterization

    Directory of Open Access Journals (Sweden)

    Harry H. Hilton

    2012-01-01

    Full Text Available Isotropic linear and nonlinear fractional derivative constitutive relations are formulated and examined in terms of many parameter generalized Kelvin models and are analytically extended to cover general anisotropic homogeneous or non-homogeneous as well as functionally graded viscoelastic material behavior. Equivalent integral constitutive relations, which are computationally more powerful, are derived from fractional differential ones and the associated anisotropic temperature-moisture-degree-of-cure shift functions and reduced times are established. Approximate Fourier transform inversions for fractional derivative relations are formulated and their accuracy is evaluated. The efficacy of integer and fractional derivative constitutive relations is compared and the preferential use of either characterization in analyzing isotropic and anisotropic real materials must be examined on a case-by-case basis. Approximate protocols for curve fitting analytical fractional derivative results to experimental data are formulated and evaluated.

  13. Structural properties of carbon nanotubes derived from 13C NMR

    KAUST Repository

    Abou-Hamad, E.

    2011-10-10

    We present a detailed experimental and theoretical study on how structural properties of carbon nanotubes can be derived from 13C NMR investigations. Magic angle spinning solid state NMR experiments have been performed on single- and multiwalled carbon nanotubes with diameters in the range from 0.7 to 100 nm and with number of walls from 1 to 90. We provide models on how diameter and the number of nanotube walls influence NMR linewidth and line position. Both models are supported by theoretical calculations. Increasing the diameter D, from the smallest investigated nanotube, which in our study corresponds to the inner nanotube of a double-walled tube to the largest studied diameter, corresponding to large multiwalled nanotubes, leads to a 23.5 ppm diamagnetic shift of the isotropic NMR line position δ. We show that the isotropic line follows the relation δ = 18.3/D + 102.5 ppm, where D is the diameter of the tube and NMR line position δ is relative to tetramethylsilane. The relation asymptotically tends to approach the line position expected in graphene. A characteristic broadening of the line shape is observed with the increasing number of walls. This feature can be rationalized by an isotropic shift distribution originating from different diamagnetic shielding of the encapsulated nanotubes together with a heterogeneity of the samples. Based on our results, NMR is shown to be a nondestructive spectroscopic method that can be used as a complementary method to, for example, transmission electron microscopy to obtain structural information for carbon nanotubes, especially bulk samples.

  14. Quasilocal energy and conserved charges derived from the gravitational action

    International Nuclear Information System (INIS)

    Brown, J.D.; York, J.W. Jr.

    1993-01-01

    The quasilocal energy of gravitational and matter fields in a spatially bounded region is obtained by employing a Hamilton-Jacobi analysis of the action functional. First, a surface stress-energy-momentum tensor is defined by the functional derivative of the action with respect to the three-metric on 3 B, the history of the system's boundary. Energy surface density, momentum surface density, and spatial stress are defined by projecting the surface stress tensor normally and tangentially to a family of spacelike two-surfaces that foliate 3 B. The integral of the energy surface density over such a two-surface B is the quasilocal energy associated with a spacelike three-surface Σ whose orthogonal intersection with 3 B is the boundary B. The resulting expression for quasilocal energy is given in terms of the total mean curvature of the spatial boundary B as a surface embedded in Σ. The quasilocal energy is also the value of the Hamiltonian that generates unit magnitude proper-time translations on 3 B in the timelike direction orthogonal to B. Conserved charges such as angular momentum are defined using the surface stress tensor and Killing vector fields on 3 B. For spacetimes that are asymptotically flat in spacelike directions, the quasilocal energy and angular momentum defined here agree with the results of Arnowitt, Deser, and Misner in the limit that the boundary tends to spatial infinity. For spherically symmetric spacetimes, it is shown that the quasilocal energy has the correct Newtonian limit, and includes a negative contribution due to gravitational binding

  15. Risk management, derivatives and shariah compliance

    Science.gov (United States)

    Bacha, Obiyathulla Ismath

    2013-04-01

    Despite the impressive growth of Islamic Banking and Finance (IBF), a number of weaknesses remain. The most important of this is perhaps the lack of shariah compliant risk management tools. While the risk sharing philosophy of Islamic Finance requires the acceptance of risk to justify returns, the shariah also requires adherents to avoid unnecessary risk-maysir. The requirement to avoid maysir is in essence a call for the prudent management of risk. Contemporary risk management revolves around financial engineering, the building blocks of which are financial derivatives. Despite the proven efficacy of derivatives in the management of risk in the conventional space, shariah scholars appear to be suspicious and uneasy with their use in IBF. Some have imposed outright prohibition of their use. This paper re-examines the issue of contemporary derivative instruments and shariah compliance. The shariah compatibility of derivatives is shown in a number of ways. First, by way of qualitative evaluation of whether derivatives can be made to comply with the key prohibitions of the sharia. Second, by way of comparing the payoff profiles of derivatives with risk sharing finance and Bai Salam contracts. Finally, the equivalence between shariah compliant derivatives like the IPRS and Islamic FX Currency Forwards with conventional ones is presented.

  16. On derived groups of division rings II

    International Nuclear Information System (INIS)

    Mahdavi Hezavehi, M.; Akbari Feyzaabaadi, S.; Mehraabaadi, M.; Hajie Abolhassan, H.

    1995-05-01

    Let D be a division ring with centre F and denote by D' the derived group (commutator subgroup) of D * = D - {0}. It is shown that if each element of D' is algebraic over F, then D is algebraic over F. It is also proved that each finite separable extension of F in D is of the form F(c) for some element c in the derived group D'. Using these results, it is shown that if each element of the derived group D' is of bounded degree over F, then D is finite dimensional over F. (author). 5 refs

  17. Derivation of GFDM Based on OFDM Principles

    Energy Technology Data Exchange (ETDEWEB)

    Hussein Moradi; Behrouz Farhang-Boroujeny

    2015-06-01

    This paper starts with discussing the principle based on which the celebrated orthogonal frequency division multiplexing (OFDM) signals are constructed. It then extends the same principle to construct the newly introduced generalized frequency division multiplexing (GFDM) signals. This novel derivation sheds light on some interesting properties of GFDM. In particular, our derivation seamlessly leads to an implementation of GFDM transmitter which has significantly lower complexity than what has been reported so far. Our derivation also facilitates a trivial understanding of how GFDM (similar to OFDM) can be applied in MIMO channels.

  18. Mechanism of Platinum Derivatives Induced Kidney Injury

    Directory of Open Access Journals (Sweden)

    Feifei YAN

    2015-09-01

    Full Text Available Platinum derivatives are the most widely used chemotherapeutic agents to treat solid tumors including ovarian, head and neck, and testicular germ cell tumors, lung cancer, and colorectal cancer. Two major problems exist, however, in the clinic use of platinum derivatives. One is the development of tumor resistance to the drug during therapy, leading to treatment failure. The other is the drug’s toxicity such as the cisplatin’s nephrotoxicity, which limits the dose that can be administered. This paper describes the mechanism of platinum derivatives induced kidney injury.

  19. Características morfológicas, histoquímicas e imunoistoquímicas dos tendões dos músculos semitendíneo e grácil: estudo comparativo entre os sexos Morphologic, histochemical, and immunohistochemical characteristics of the tendons of the semitendinosus and gracilis muscles: comparative study between men and women

    Directory of Open Access Journals (Sweden)

    Edgard dos Santos Pereira Júnior

    2008-05-01

    Full Text Available OBJETIVO: Comparar, entre os sexos, as características morfológicas, histoquímicas e imunoistoquímicas dos tendões dos músculos semitendíneo e grácil a serem utilizados como auto-enxerto nas cirurgias de reconstrução do ligamento cruzado anterior. MÉTODOS: Amostras dos tendões dos músculos semitendíneo e grácil de 36 pacientes (36 joelhos foram avaliadas. As idades variaram de 15 a 46 anos, com média de 29,3 anos. Com relação à cor, 33 pacientes eram brancos e três não brancos. Quanto ao lado, eram 23 joelhos direitos e 13 esquerdos. Os pacientes foram divididos em dois grupos, sexo masculino (n = 20 e feminino (n = 16. As amostras dos tendões foram submetidas à análise histológica, histoquímica e imunoistoquímica. RESULTADOS: Não se observaram diferenças estatisticamente significantes em relação à idade, ao sexo, à cor, ao lado, ao processo inflamatório, à vascularização, e à alcianofilia entre os grupos avaliados. Houve aumento da celularidade nos tendões do músculo semitendíneo em relação aos tendões do músculo grácil (sexo masculino p = 0,03 e sexo feminino p = 0,22. Pôde-se observar tendência nas mulheres à maior presença de calcificações dos tendões dos músculos semitendíneo e grácil (p = 0,06 e p = 0,09, e ao aumento da degeneração das fibras colágenas dos tendões do músculo semitendíneo (p = 0,06. Em relação à presença de receptores de estrógeno nos tendões dos músculos semitendíneo e grácil, observou-se aumento do número de receptores nos pacientes do sexo masculino. CONCLUSÃO: Observaram-se, entre os sexos, diferenças morfológicas, histoquímicas e imunoistoquímicas no tendão do músculo semitendíneo entre o tendão dos músculos grácil e semitendíneo no sexo masculino.OBJECTIVE: To compare the morphologic, histochemical, and immunohistochemical characteristics of the tendons of the semitendinosus and the gracilis muscles to be used as autograft in anterior

  20. A diagnostic approach to obtaining planetary boundary layer winds using satellite-derived thermal data

    Science.gov (United States)

    Belt, Carol L.; Fuelberg, Henry E.

    1984-01-01

    The feasibility of using satellite derived thermal data to generate realistic synoptic scale winds within the planetary boundary layer (PBL) is examined. Diagnostic modified Ekman wind equations from the Air Force Global Weather Central (AFGWC) Boundary Layer Model are used to compute winds at seven levels within the PBL transition layer (50 m to 1600 m AGL). Satellite derived winds based on 62 predawn TIROS-N soundings are compared to similarly derived wind fields based on 39 AVE-SESAME II rawinsonde (RAOB) soundings taken 2 h later. Actual wind fields are also used as a basis for comparison. Qualitative and statistical comparisons show that the Ekman winds from both sources are in very close agreement, with an average vector correlation coefficient of 0.815. Best results are obtained at 300 m AGL. Satellite winds tend to be slightly weaker than their RAOB counterparts and exhibit a greater degree of cross-isobaric flow. The modified Ekman winds show a significant improvement over geostrophic values at levels nearest the surface.