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Sample records for irradiated ultra-high molecular

  1. Physico-chemical characterization of polyethylene of ultra high molecular weight modified with gamma irradiation and heavy ions

    International Nuclear Information System (INIS)

    Lagarde, M; Del Grosso, M; Fasce, D; Dommarco, R; Laino, S; Fasce, L.A

    2012-01-01

    The ultra high molecular weight polyethylene (UHMWPE) is a biomaterial widely used in total joint replacement. In this work, the effect of two different irradiation techniques on UHMWPE is analyzed. One technique involves gamma irradiation (γ) followed by a thermal treatment, thus modifying the material bulk. The other implies swift heavy ion irradiation (SHI), which have an effect only on the near surface layers. The surface nanomechanical properties are evaluated from depth sensing indentation experiments, while changes in crystallinity and chemical structure are determined by DSC and Raman spectroscopy. The results show that even when both techniques are able to improve the UHMWPE wear behavior, the effect on other mechanical properties and molecular structure modification is different. The γ irradiated sample exhibits lower crystallinity, hardness and modulus than the pristine UHMWPE, while the SHI irradiated sample exhibits higher crystallinity and enhanced mechanical properties than the later

  2. The effect of gamma irradiation and shelf aging in air on the oxidation of ultra-high molecular weight polyethylene

    International Nuclear Information System (INIS)

    Al-Ma'adeed, M.A.; Al-Qaradawi, I.Y.; Madi, N.; Al-Thani, N.J.

    2006-01-01

    This study has investigated the effect of shelf aging, for up to one year in air, on the properties of gamma-irradiated ultra-high molecular weight polyethylene (UHMWPE). A variety of techniques were used to characterize the properties of treated samples. Differential scanning calorimetery (DSC) was used to characterize the morphology. The extent of cross-linking in a polymer network was detected by swelling measurements. The durometer hardness test was used to measure the relative hardness of this material, and changes in density were also measured. Results from all these measurements were combined to explain the changes in the microstructure of the aged, irradiated UHMWPE. This study shows that crystallinity is increased with radiation dose and with aging due to chain scission, which leads to a reduction in the molecular weight of the material. This allows the chains to rearrange to form crystalline regions. Positron annihilation lifetime spectroscopy confirms these conclusions. Fractional free volumes have been deduced from lifetime parameters, which correlate with the data obtained by the other techniques

  3. Study of crosslinking onset and hydrogen annealing of ultra-high molecular weight polyethylene irradiated with high-energy protons

    Science.gov (United States)

    Wilson, John Ford

    1997-09-01

    Ultra high molecular weight polyethylene (UHMW-PE) is used extensively in hip and knee endoprostheses. Radiation damage from the sterilization of these endoprostheses prior to surgical insertion results in polymer crosslinking and decreased oxidative stability. The motivation for this study was to determine if UHMW-PE could be crosslinked by low dose proton irradiation with minimal radiation damage and its subsequent deleterious effects. I found that low dose proton irradiation and post irradiation hydrogen annealing did crosslink UHMW-PE and limit post irradiation oxidation. Crosslinking onset was investigated for UHMW-PE irradiated with 2.6 and 30 MeV H+ ions at low doses from 5.7 × 1011-2.3 × 1014 ions/cm2. Crosslinking was determined from gel permeation chromatography (GPC) of 1,2,4 trichlorobenzene sol fractions and increased with dose. Fourier transform infrared spectroscopy (FTIR) showed irradiation resulted in increased free radicals confirmed from increased carbonyl groups. Radiation damage, especially at the highest doses observed, also showed up in carbon double bonds and increased methyl end groups. Hydrogen annealing after ion irradiation resulted in 40- 50% decrease in FTIR absorption associated with carbonyl. The hydrogen annealing prevented further oxidation after aging for 1024 hours at 80oC. Hydrogen annealing was successful in healing radiation damage through reacting with the free radicals generated during proton irradiation. Polyethylenes, polyesters, and polyamides are used in diverse applications by the medical profession in the treatment of orthopedic impairments and cardiovascular disease and for neural implants. These artificial implants are sterilized with gamma irradiation prior to surgery and the resulting radiation damage can lead to accelerated deterioration of the implant properties. The findings in this study will greatly impact the continued use of these materials through the elimination of many problems associated with radiation

  4. Sintering of ultra high molecular weight polyethylene

    Indian Academy of Sciences (India)

    Abstract. Ultra high molecular weight polyethylene (UHMWPE) is a high performance polymer having low coefficient of friction, good abrasion resistance, good chemical ... In this study, we report our results on compaction and sintering behaviour of two grades of UHMWPE with reference to the powder morphology, sintering ...

  5. The Influence of Irradiation and Accelerated Aging on the Mechanical and Tribological Properties of the Graphene Oxide/Ultra-High-Molecular-Weight Polyethylene Nanocomposites

    Directory of Open Access Journals (Sweden)

    Guodong Huang

    2016-01-01

    Full Text Available Graphene oxide/ultra-high-molecular-weight polyethylene (GO/UHMWPE nanocomposite is a potential and promising candidate for artificial joint applications. However, after irradiation and accelerated aging, the mechanical and tribological behaviors of the nanocomposites are still unclear and require further investigation. GO/UHMWPE nanocomposites were successfully fabricated using ultrasonication dispersion, ball-milling, and hot-pressing process. Then, the nanocomposites were irradiated by gamma ray at doses of 100 kGy. Finally, GO/UHMWPE nanocomposites underwent accelerated aging at 80°C for 21 days in air. The mechanical and tribological properties of GO/UHMWPE nanocomposites have been evaluated after irradiation and accelerated aging. The results indicated that the incorporation of GO could enhance the mechanical, wear, and antiscratch properties of UHMWPE. After irradiation, these properties could be further enhanced, compared to unirradiated ones. After accelerated aging, however, these properties have been significantly reduced when compared to unirradiated ones. Moreover, GO and irradiation can synergistically enhance these properties.

  6. Measurements of Free Radical in Vitamin E-Doped Ultra-High Molecular Weight Polyethylene: Dependence on Materials Processing and Irradiation Environments

    International Nuclear Information System (INIS)

    Ridley, M. D.

    2006-01-01

    In an effort to combat oxidation of the load-bearing, polyethylene (PE) components of total hip- and knee-joint replacement devices, antioxidant such as vitamin E (α-Tocopherol (α-T)) has been introduced into polymer matrix. In this study we investigated effect of α-T on free radicals in medical grade ultra-high molecular weight polyethylene (UHMWPE), GUR 1020 resin. Since oxidation resistance depends on radical reaction, we used electron spin resonance (ESR) technique for direct detection of free radicals before and after irradiation. High concentration (20% by vol.) of α-T was used so its ESR signal (due to α-T-O degree radical) could be distinguished among the overwhelming signals due to PE radicals. Two groups of samples were investigated. In one group, samples were prepared from blends of α-T and UHMWPE powder (α-T-P), and in the second group, from compression molded blocks (α-T-B). In each group, samples were γ-irradiated in sealed packages filled with N 2 , or in open air, and free radicals were measured in open air environment as a function of time. Also included in this study were α-T, and powder resin and compression molded blocks without any α-T. Following irradiation in air, α-T-P and α-T produced identical ESR spectra showing characteristic feature of α-T-O degree radical. Absence of PE radicals in the ESR signals suggests quenching/repairing of PE radicals by α-T in presence of oxygen. However, when irradiation was performed in N 2 , ESR signals of α-T-P exhibited superimposed resonance lines due to PE and α-T-O degree radicals. Furthermore, presence of a-T or α-T-O degree radicals did not prevent subsequent oxidation of PE radicals in producing stable, oxygen-induced radicals (OIR). Post-irradiation oxidation index measured by FTIR, however, did not show any difference between these samples. Compression molded samples, with or without α-T, produced ESR spectra showing features characteristics of PE radicals only, and there was no

  7. Measurements of free radical in vitamin E-doped ultra-high molecular weight polyethylene: Dependence on materials processing and irradiation environments

    Energy Technology Data Exchange (ETDEWEB)

    Ridley, M.D. [Department of Physics, Biomaterials Research Laboratory, University of Memphis, 216 Manning Hall, Memphis, TN 38152 (United States); Jahan, M.S. [Department of Physics, Biomaterials Research Laboratory, University of Memphis, 216 Manning Hall, Memphis, TN 38152 (United States)], E-mail: mjahan@memphis.edu

    2007-12-15

    Ultra-high molecular weight polyethylene (UHMWPE), doped with vitamin E ({alpha}-tocopherol ({alpha}-T)), was irradiated with gamma rays in nitrogen (N{sub 2}) or air, and the resulting free radicals were detected in air using an electron spin resonance (ESR) technique. Two groups of samples were investigated. In one group, samples were prepared from blends of {alpha}-T (20 wt%) and UHMWPE powder (PPE-{alpha}-T) and, in the other, from compression molded blocks (CMPE-{alpha}-T). The CMPE-{alpha}-T blocks contained 0% (control), 0.5%, 1.0%, 10.0%, 15.0%, 20.0% and 25.0% {alpha}-T by weight. When irradiation was performed in air, the ESR spectrum of powder samples showed the presence of only vitamin E radical (tocopheroxyl, {alpha}-T-O{sup {center_dot}}), and there was no detectable signal due to PE radicals (alkyl/allyl). Most likely, all PE radicals were quenched by vitamin E during irradiation in air. However, when irradiation was performed in N{sub 2}, composite ESR spectra showed the presence of both PE and {alpha}-T-O{sup {center_dot}} radicals. Compared to the control (PPE, 0% {alpha}-T) PE radicals in PPE-20% {alpha}-T were found to be significantly reduced or quenched by {alpha}-T. The presence of {alpha}-T in powder samples, however, did not affect the long-term (71 days in this study) oxidation behavior of the PE radicals. Compression molded samples, with and without {alpha}-T, produced identical ESR spectra irrespective of their irradiation environment N{sub 2} or air. However, radical concentration, measured immediately after irradiation, was found to be an order of magnitude less in CMPE-{alpha}-T than in the control (CMPE-0% {alpha}-T). They also evidenced identical structural changes in the respective ESR spectra during subsequent oxidation for 24 days in open air. These observations suggest that {alpha}-T can effectively quench a significant fraction of PE radicals during irradiation, but has no measurable effect on subsequent reactions. No

  8. Properties of crosslinked ultra-high-molecular-weight polyethylene.

    Science.gov (United States)

    Lewis, G

    2001-02-01

    Substantially reducing the rate of generation of wear particles at the surfaces of ultra-high-molecular-weight polyethylene (UHMWPE) orthopedic implant bearing components, in vivo, is widely regarded as one of the most formidable challenges in modern arthroplasty. In the light of this, much research attention has been paid to the myriad of endogenous and exogenous factors that have been postulated to affect this wear rate, one such factor being the polymer itself. In recent years, there has been a resurgence of interest in crosslinking the polymer as a way of improving its properties that are considered relevant to its use for fabricating bearing components. Such properties include wear resistance, fatigue life, and fatigue crack propagation rate. Although a large volume of literature exists on the topic on the impact of crosslinking on the properties of UHMWPE, no critical appraisal of this literature has been published. This is one of the goals of the present article, which emphasizes three aspects. The first is the trade-off between improvement in wear resistance and depreciation in other mechanical and physical properties. The second aspect is the presentation of a method of estimating the optimal value of a crosslinking process variable (such as dose in radiation-induced crosslinking) that takes into account this trade-off. The third aspect is the description of a collection of under- and unexplored research areas in the field of crosslinked UHMWPE, such as the role of starting resin on the properties of the crosslinked polymer, and the in vitro evaluation of the wear rate of crosslinked tibial inserts and other bearing components that, in vivo, are subjected to nearly unidirectional motion.

  9. Effect of electron beam radiation on the structure and mechanical properties of ultra high molecular weight polyethylene fibers

    International Nuclear Information System (INIS)

    Li Shujun; Sun Weijun; Liu Xiuju; Gao Yongzhong; Li Huisheng

    1998-01-01

    Ultra high molecular weight polyethylene fibers have been crosslinked by electron beam. The structure and mechanical properties of them have been investigated in different irradiation atmospheres. The obtained results show that the gel content and crosslinking density increase with the increase of dose, the swelling ratio and average molecular weight of crosslinked net decrease with the increase of dose, the tensile strength and failure elongation decrease with the increase of dose, the tensile modulus increases with the increase of dose. When the samples are irradiated in air, vacuum and acetylene atmospheres, the effect of irradiation in acetylene atmosphere is best

  10. Ballistic behavior of ultra-high molecular weight polyethylene composite: effect of gamma radiation

    International Nuclear Information System (INIS)

    Alves, Andreia L. dos Santos; Nascimento, Lucio F.C.; Suarez, Joao C. Miguez; lucio2002bol.com.br

    2003-01-01

    Since World War II, textile composites have been used as ballistic armor. Ultra-high molecular weight polyethylene (UHMWPE) fibers are used in the production of armor materials. As they have been developed and commercialized only recently, there is not enough information about the effect of environmental agents in the ballistic performance of UHMWPE composites. In the present work, was evaluated the ballistic behavior of composite plates manufactured with UHMWPE fibers after exposure to gamma radiation. The ballistic tests results were related to the macromolecular alterations induced by the radiation through mechanical (hardness, impact and flexure) and physicochemical (Ftir/Mir. DSC and TGA) testing. It was observed that irradiation induces changes in the UHMWPE, degrading the ballistic performance of the composite. These results are presented and discussed. (author)

  11. Macroradical reaction in ultra-high molecular weight polyethylene in the presence of vitamin E

    International Nuclear Information System (INIS)

    Jahan, M.S.; Walters, B.M.

    2011-01-01

    Free radical measurements in compression molded ultra-high molecular weight polyethylene (UHMWPE), which contained vitamin E (α-tocopherol (α-T)), was performed using electron spin resonance (ESR) technique in air at room temperature following gamma irradiation (25-32 kGy) in N 2 . The vitamin E was incorporated into one set of samples by blending UHMWPE resin with vitamin E (1 and 10 wt%), then compression molded into a solid and then irradiated. Another set of samples had vitamin E incorporated into them by diffusing vitamin E at 100 o C for 2 h after irradiation. Compared to a control (with no vitamin E), the vitamin E-containing UHMWPE (α-TPE) samples suffered a partial loss of PE radicals, but this loss only occurred during or immediately after irradiation (before exposure to air). Subsequently, when all blended samples were exposed to air, the remaining radicals in each sample decayed to the well-known OIR, R1 (- · CH-[CH=CH-] m -) and R2 ( · OCH-[CH=CH-] m -) radicals. However, because of the initial loss or partial quenching, α-TPE produced a lower concentration of OIR (measured over a four-year period), but no difference was found between 1% and 10% α-TPEs. In the diffused α-TPE, similar OIR was also found when tested after four months of post-treatment exposure to air.

  12. Macroradical reaction in ultra-high molecular weight polyethylene in the presence of vitamin E

    Energy Technology Data Exchange (ETDEWEB)

    Jahan, M.S., E-mail: mjahan@memphis.ed [Department of Physics, Biomaterials Research Laboratory, University of Memphis, 216 Manning Hall, Memphis, TN 38152 (United States); Walters, B.M. [Department of Physics, Biomaterials Research Laboratory, University of Memphis, 216 Manning Hall, Memphis, TN 38152 (United States)

    2011-02-15

    Free radical measurements in compression molded ultra-high molecular weight polyethylene (UHMWPE), which contained vitamin E ({alpha}-tocopherol ({alpha}-T)), was performed using electron spin resonance (ESR) technique in air at room temperature following gamma irradiation (25-32 kGy) in N{sub 2}. The vitamin E was incorporated into one set of samples by blending UHMWPE resin with vitamin E (1 and 10 wt%), then compression molded into a solid and then irradiated. Another set of samples had vitamin E incorporated into them by diffusing vitamin E at 100 {sup o}C for 2 h after irradiation. Compared to a control (with no vitamin E), the vitamin E-containing UHMWPE ({alpha}-TPE) samples suffered a partial loss of PE radicals, but this loss only occurred during or immediately after irradiation (before exposure to air). Subsequently, when all blended samples were exposed to air, the remaining radicals in each sample decayed to the well-known OIR, R1 (-{sup {center_dot}C}H-[CH=CH-]{sub m}-) and R2 ({sup {center_dot}O}CH-[CH=CH-]{sub m}-) radicals. However, because of the initial loss or partial quenching, {alpha}-TPE produced a lower concentration of OIR (measured over a four-year period), but no difference was found between 1% and 10% {alpha}-TPEs. In the diffused {alpha}-TPE, similar OIR was also found when tested after four months of post-treatment exposure to air.

  13. Thermal characterization of Ag and Ag + N ion implanted ultra-high molecular weight polyethylene (UHMWPE)

    Science.gov (United States)

    Sokullu Urkac, E.; Oztarhan, A.; Tihminlioglu, F.; Kaya, N.; Ila, D.; Muntele, C.; Budak, S.; Oks, E.; Nikolaev, A.; Ezdesir, A.; Tek, Z.

    2007-08-01

    Most of total hip joints are composed of ultra-high molecular weight polyethylene (UHMWPE). However, as ultra-high molecular weight polyethylene is too stable in a body, wear debris may accumulate and cause biological response such as bone absorption and loosening of prosthesis. In this study, ultra-high molecular weight polyethylene samples were Ag and Ag + N hybrid ion implanted by using MEVVA ion implantation technique to improve its surface properties. Samples were implanted with a fluence of 1017 ion/cm2 and extraction voltage of 30 kV. Implanted and unimplanted samples were investigated by thermo-gravimetry analysis (TGA), differential scanning calorimetry (DSC), X-ray diffraction (XRD) analysis, scanning electron microscopy (SEM), optical microscopy (OM) and contact Angle measurement. Thermal characterization results showed that the ion bombardment induced an increase in the % crystallinity, onset and termination degradation temperatures of UHMWPE.

  14. Thermal characterization of Ag and Ag + N ion implanted ultra-high molecular weight polyethylene (UHMWPE)

    Energy Technology Data Exchange (ETDEWEB)

    Sokullu Urkac, E. [Department of Materials Science, Izmir High Technology Institute, Gulbahcekoyu Urla, Izmir (Turkey)]. E-mail: emelsu@gmail.com; Oztarhan, A. [Bioengineering Department, Ege University, Bornova, Izmir 35100 (Turkey); Tihminlioglu, F. [Department of Chemical Engineering, Izmir High Technology Institute, Gulbahcekoyu Urla, Izmir (Turkey); Kaya, N. [Bioengineering Department, Ege University, Bornova, Izmir 35100 (Turkey); Ila, D. [Center for Irradiation of Materials, Alabama A and M University, Normal AL 35762 (United States); Muntele, C. [Center for Irradiation of Materials, Alabama A and M University, Normal AL 35762 (United States); Budak, S. [Center for Irradiation of Materials, Alabama A and M University, Normal AL 35762 (United States); Oks, E. [H C Electronics Institute, Tomsk (Russian Federation); Nikolaev, A. [H C Electronics Institute, Tomsk (Russian Federation); Ezdesir, A. [R and D Department, PETKIM Holding A.S., Aliaga, Izmir 35801 (Turkey); Tek, Z. [Department of Physics, Celal Bayar University, Manisa (Turkey)

    2007-08-15

    Most of total hip joints are composed of ultra-high molecular weight polyethylene (UHMWPE ). However, as ultra-high molecular weight polyethylene is too stable in a body, wear debris may accumulate and cause biological response such as bone absorption and loosening of prosthesis. In this study, ultra-high molecular weight polyethylene samples were Ag and Ag + N hybrid ion implanted by using MEVVA ion implantation technique to improve its surface properties. Samples were implanted with a fluence of 10{sup 17} ion/cm{sup 2} and extraction voltage of 30 kV. Implanted and unimplanted samples were investigated by thermo-gravimetry analysis (TGA), differential scanning calorimetry (DSC), X-ray diffraction (XRD) analysis, scanning electron microscopy (SEM), optical microscopy (OM) and contact Angle measurement. Thermal characterization results showed that the ion bombardment induced an increase in the % crystallinity, onset and termination degradation temperatures of UHMWPE.

  15. Ultra-high Density SNParray in Neuroblastoma Molecular Diagnostics

    Directory of Open Access Journals (Sweden)

    Inge M. Ambros

    2014-08-01

    Full Text Available Neuroblastoma serves as a paradigm for applying tumor genomic data for determining patient prognosis and thus for treatment allocation. MYCN status, i.e. amplified vs. non-amplified, was one of the very first biomarkers in oncology to discriminate aggressive from less aggressive or even favorable clinical courses of neuroblastoma. However, MYCN amplification is by far not the only genetic change associated with unfavorable clinical courses: so called segmental chromosomal aberrations, i.e. gains or losses of chromosomal fragments, can also indicate tumor aggressiveness. The clinical use of these genomic aberrations has, however, been hampered for many years by methodical and interpretational problems. Only after reaching worldwide consensus on markers, methodology, and data interpretation, information on SCAs has recently been implemented in clinical studies. Now, a number of collaborative studies within COG, GPOH and SIOPEN use genomic information to stratify therapy for patients with localized and metastatic disease. Recently, new types of DNA based aberrations influencing the clinical behavior of neuroblastomas have been described. Deletions or mutations of genes like ATRX and a phenomenon referred to as chromothripsis are all assumed to correlate with an unfavorable clinical behavior. However, these genomic aberrations need to be scrutinized in larger studies applying the most appropriate techniques. Single nucleotide polymorphism (SNP arrays have proven successful in deciphering genomic aberrations of cancer cells; these techniques, however, are usually not applied in the daily routine. Here, we present an ultra-high density (UHD SNParray technique which is, because of its high specificity and sensitivity and the combined copy number and allele information, highly appropriate for the genomic diagnosis of neuroblastoma and other malignancies.

  16. The adhesive properties of chlorinated ultra-high molecular weight polyethylene

    NARCIS (Netherlands)

    Menting, H.N.A.M.; Voets, P.E.L.; Lemstra, P.J.

    1995-01-01

    Ultra-high molecular weight polyethylene (UHMW-PE) is well known for its abrasion and chemical resistance. Recently we developed a new application for UHMW-PE as a liner in elastomeric hoses. It was found that the adhesion between UHMW-PE and elastomers such as ethylene-propylene-diene monomer

  17. Extension induced phase separation and crystallization in semidilute solutions of ultra high molecular weight polyethylene

    DEFF Research Database (Denmark)

    Wingstrand, Sara Lindeblad; Imperiali, Luna; Stepanyan, Roman

    2018-01-01

    Abstract We investigate the influence of controlled uniaxial extension on various flow induced phenomena in semidilute solutions of ultra high molecular weight polyethylene (UHMwPE). Concentrations range from 9 w% to 29 w% and the choice of solvent is paraffin oil (PO). The start-up extensional b...

  18. Nanometer size wear debris generated from ultra high molecular weight polyethylene in vivo

    Czech Academy of Sciences Publication Activity Database

    Lapčíková, Monika; Šlouf, Miroslav; Dybal, Jiří; Zolotarevova, E.; Entlicher, G.; Pokorný, D.; Gallo, J.; Sosna, A.

    2009-01-01

    Roč. 266, 1-2 (2009), s. 349-355 ISSN 0043-1648 R&D Projects: GA MŠk 2B06096 Institutional research plan: CEZ:AV0Z40500505 Keywords : ultra high molecular weight polyethylene * nanometer size wear debris * morphology of wear particles Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.771, year: 2009

  19. Laser surface modification of ultra-high-molecular-weight polyethylene (UHMWPE) for biomedical applications

    International Nuclear Information System (INIS)

    Riveiro, A.; Soto, R.; Val, J. del; Comesaña, R.; Boutinguiza, M.; Quintero, F.; Lusquiños, F.; Pou, J.

    2014-01-01

    Ultra-high-molecular-weight polyethylene (UHMWPE) is a synthetic polymer used for biomedical applications because of its high impact resistance, ductility and stability in contact with physiological fluids. Therefore, this material is being used in human orthopedic implants such as total hip or knee replacements. Surface modification of this material relates to changes on its chemistry, microstructure, roughness, and topography, all influencing its biological response. Surface treatment of UHMWPE is very difficult due to its high melt viscosity. This work presents a systematic approach to discern the role of different laser wavelengths (λ = 1064, 532, and 355 nm) on the surface modification of carbon coated UHMWPE samples. Influence of laser processing conditions (irradiance, pulse frequency, scanning speed, and spot overlapping) on the surface properties of this material was determined using an advanced statistical planning of experiments. A full factorial design of experiments was used to find the main effects of the processing parameters. The obtained results indicate the way to maximize surface properties which largely influence cell–material interaction.

  20. Laser surface modification of ultra-high-molecular-weight polyethylene (UHMWPE) for biomedical applications

    Energy Technology Data Exchange (ETDEWEB)

    Riveiro, A., E-mail: ariveiro@uvigo.es [Applied Physics Department, University of Vigo, ETSII, Lagoas-Marcosende, 9, Vigo 36310 (Spain); Centro Universitario de la Defensa, Escuela Naval Militar, Plaza de España 2, 36920 Marín (Spain); Soto, R.; Val, J. del; Comesaña, R.; Boutinguiza, M.; Quintero, F.; Lusquiños, F.; Pou, J. [Applied Physics Department, University of Vigo, ETSII, Lagoas-Marcosende, 9, Vigo 36310 (Spain)

    2014-05-01

    Ultra-high-molecular-weight polyethylene (UHMWPE) is a synthetic polymer used for biomedical applications because of its high impact resistance, ductility and stability in contact with physiological fluids. Therefore, this material is being used in human orthopedic implants such as total hip or knee replacements. Surface modification of this material relates to changes on its chemistry, microstructure, roughness, and topography, all influencing its biological response. Surface treatment of UHMWPE is very difficult due to its high melt viscosity. This work presents a systematic approach to discern the role of different laser wavelengths (λ = 1064, 532, and 355 nm) on the surface modification of carbon coated UHMWPE samples. Influence of laser processing conditions (irradiance, pulse frequency, scanning speed, and spot overlapping) on the surface properties of this material was determined using an advanced statistical planning of experiments. A full factorial design of experiments was used to find the main effects of the processing parameters. The obtained results indicate the way to maximize surface properties which largely influence cell–material interaction.

  1. Dosimetric features and kinetic analysis of thermoluminescence from ultra-high molecular weight polyethylene

    Science.gov (United States)

    Chithambo, M. L.

    2012-08-01

    Thermoluminescence (TL) from beta irradiated ultra-high molecular weight polyethylene has been studied for measurements between 30 and 200 °C. An aliquot studied in this work produced TL glow curves consisting of two peaks, the main peak at 88 °C and a weaker intensity peak at 148 °C for heating at 1 °C s-1 following an excitation dose of 215 Gy. The position of the main peak is poorly reproducible for heating rates of 0.2 and 0.6 °C s-1 investigated with the peak position decreasing when the sample is freshly irradiated and the TL re-measured. The said change in peak position is however less of an effect for measurements made at 1 °C s-1 with the peak position being fairly reproducible in this case. Further measurements of the dosimetric properties of ultra-high molecular weight polyethylene showed that its dose response is linear from 26 Gy to about 161 Gy but exhibits slower growth in intensity with dose from about 860 Gy after regions of sub- and supra-linearity in between. If the TL is not measured immediately after irradiation, the signal fades with the delay approximately exponentially. In addition, a number of tests including phosphorescence analysis showed the possibility that the order of kinetics might not be unique but sensitive to several factors including measurement temperature. Thus for instance, the dependence of the peak position on the stop temperature in the partial heating procedure Tm - Tstop implied first-order kinetics but analysis of the geometrical factor μg for the same set of data gave μg = 0.46 ± 0.03 a value corresponding to characteristics somewhat intermediate between first and second order. In comparison, the results of analysis of the phosphorescence recorded at several temperatures on the rising edge of the main peak were only in agreement for measurements at 40 °C with general-order analysis suggesting second-order kinetics apply as did TL-like transformation of the monotonic phosphorescence decay. Both results were

  2. Evaluation of environmental degradation effects in morphology of ultra-high molecular weight polyethylene (UHMWPE) fibers

    International Nuclear Information System (INIS)

    Vivas, Viviane; Zylberberg, Marcel P.; Cardoso, Andre Luis V.; Pereira, Iaci M.; Weber, Ricardo P.; Suarez, Joao C. Miguez

    2015-01-01

    This study aims to evaluate changes in the morphology of ultra-high molecular weight polyethylene fiber (UHMWPE), before and after exposure to environmental agents. Fibers produced by two different manufacturers were analyzed. To characterize the morphology, we used the technique of small angle x-ray scattering (SAXS). The results demonstrate that the original morphology of the fibers was UHMWPE affected by the defects caused by exposure to environmental agents. (author)

  3. Silver Nanoparticles Modification of Ultra High Molecular Weight Polyethylene in Non-Aqueous Medium

    OpenAIRE

    V. N. Glushko; L. I. Blokhina; E. E. Anisimova; M. V. Bogdanovskaya; V. I. Kozhukhov; T. A. Cherdyntseva

    2016-01-01

    A series of experiments for obtaining modified with silver nanoparticles ultra-high molecular weight polyethylene (UHMWPE) is done. Optimal precursors are silver trifluoroacetate, silver nitrate and silver methanesulfonate. Three variants of UHMWPE modification is studied: 1) the polyol synthesis, 2) polymer processing silver nanoparticle colloid and 3) reduction of silver salt solution in the UHMWPE polymer matrix. It is found that the last method is optimal. The specific surface of obtained...

  4. Effects of ionizing radiation on the properties of ultra-high molecular weight polyethylene (PE-UHMW)

    International Nuclear Information System (INIS)

    Kurth, M.

    1990-01-01

    Ultra high molecular weight polyethylene (PE-UHMW) is used in most artificial joint replacement devices. Prior to implantation in biological environment, radiatin sterilization by 60 Co or electron beam is common. It is well known that polyethylene exposed to ionizing radiation of any sort undergo physical changes due to chain scission and/or crosslinking. PE-UHMW sheets, 8 mm thick, were either 60 Co or electron beam irradiated, in the range of 10-150 kGy under air or nitrogen atmoshere. The crystallinity of the irradiated samples increases with the irradiation dose. The chain scission/crosslinking events ratio determine the network structure and the sol/gel ratio. The latter was found to depend on irradiation dose, radiation atmosphere and sample thickness. Moreover 60 Co-irradiation is about 5 times more effective in forming PE-UHMW gel than electron-irradiation. Besides the degree of crosslinking, the molecular weight distribution is the main determinant of the structural properties of PE-UHMW. Low molecular weight fractions were also found. Using a dose of 30 kGy ( 60 Co in air), the average molecular weight of the soluble part after extraction decreased from originally 2.3 million g/mol to 170.000 g/mol, corresponding to a factor of about 10. These changes in molecular weight have a strong influence on the mechanical properties of PE-UHMW. Crosslinking slightly increases the yield strength, while the elongation at break decreases. Long-term compressive creep is reduced if the material is irradiated. Obviously, increased crystallinity after oxidative chain scission affects a higher deformation resistance. Radiation crosslinked structures cause a significant increase in abrasion resistance. The above described structural changes occur even upon irradiation of very low doses as used during sterilization. This study will enable to reduce the radiation sterilization damage and thus to gain long term stability of PE-UHMW medical devices. (orig./BBR)

  5. Comparison between bulk and thin foil ion irradiation of ultra high purity Fe

    Energy Technology Data Exchange (ETDEWEB)

    Prokhodtseva, A., E-mail: anna.prokhodtseva@psi.ch [Ecole Polytechnique Fédérale de Lausanne (EPFL), Centre de Recherches en Physique des Plasmas, Association Euratom-Confédération Suisse, 5232 Villigen PSI (Switzerland); Décamps, B. [Centre de Spectrométrie Nucléaire et de Spectrométrie de Masse (CSNSM), CNRS-IN2P3-Univ. Paris-Sud 11, UMR 8609, Bât. 108, 91405 Orsay (France); Schäublin, R. [Ecole Polytechnique Fédérale de Lausanne (EPFL), Centre de Recherches en Physique des Plasmas, Association Euratom-Confédération Suisse, 5232 Villigen PSI (Switzerland)

    2013-11-15

    Accumulation of radiation damage in ultra high purity iron under self ion irradiation without and with simultaneous He implantation was investigated in bulk and thin foil form to assess, on the one hand, the effect of free surfaces and, on the other hand, the influence of He. Specimens were irradiated at room temperature to a dose of 0.8 dpa and ∼900 appm He content. We found in thin foils after irradiation with single beam a majority of a{sub 0} 〈1 0 0〉 type loops, while in the presence of He it is the ½ a{sub 0} 〈1 1 1〉 type loops that prevail. In single beam irradiated bulk samples most of the loops are of ½ a{sub 0} 〈1 1 1〉 type. In both bulk and thin foils density of defects visible in transmission electron microscope is considerably higher when He is implanted with prevailing ½ a{sub 0} 〈1 1 1〉 dislocation loops, indicating that He stabilizes them.

  6. Survival of tumor cells after proton irradiation with ultra-high dose rates

    International Nuclear Information System (INIS)

    Auer, Susanne; Hable, Volker; Greubel, Christoph; Drexler, Guido A; Schmid, Thomas E; Belka, Claus; Dollinger, Günther; Friedl, Anna A

    2011-01-01

    Laser acceleration of protons and heavy ions may in the future be used in radiation therapy. Laser-driven particle beams are pulsed and ultra high dose rates of >10 9 Gy s -1 may be achieved. Here we compare the radiobiological effects of pulsed and continuous proton beams. The ion microbeam SNAKE at the Munich tandem accelerator was used to directly compare a pulsed and a continuous 20 MeV proton beam, which delivered a dose of 3 Gy to a HeLa cell monolayer within < 1 ns or 100 ms, respectively. Investigated endpoints were G2 phase cell cycle arrest, apoptosis, and colony formation. At 10 h after pulsed irradiation, the fraction of G2 cells was significantly lower than after irradiation with the continuous beam, while all other endpoints including colony formation were not significantly different. We determined the relative biological effectiveness (RBE) for pulsed and continuous proton beams relative to x-irradiation as 0.91 ± 0.26 and 0.86 ± 0.33 (mean and SD), respectively. At the dose rates investigated here, which are expected to correspond to those in radiation therapy using laser-driven particles, the RBE of the pulsed and the (conventional) continuous irradiation mode do not differ significantly

  7. Flexible mechanoprosthesis made from woven ultra-high-molecular-weight polyethylene fibres : proof of concept in a chronic sheep model

    NARCIS (Netherlands)

    Basir, Amir; Grobben, Remco B.; Cramer, Maarten Jan; van Herwaarden, Joost A.; Vink, Aryan; Pasterkamp, Gerard; Kluin, Jolanda; Gründeman, Paul F.

    2017-01-01

    OBJECTIVES: Ultra-high-molecular-weight polyethylene (UHMWPE) fibres are flexible, have high tensile strength, and platelet and bacterial adhesion is low. Therefore, UHMWPE may overcome limitations of current mechanical valves and bioprostheses. In this study, the biocompatibility and functionality

  8. Equal channel angular extrusion of ultra-high molecular weight polyethylene

    Energy Technology Data Exchange (ETDEWEB)

    Reinitz, Steven D., E-mail: Steven.D.Reinitz.TH@Dartmouth.edu; Engler, Alexander J.; Carlson, Evan M.; Van Citters, Douglas W.

    2016-10-01

    Ultra-high molecular weight polyethylene (UHMWPE), a common bearing surface in total joint arthroplasty, is subject to material property tradeoffs associated with conventional processing techniques. For orthopaedic applications, radiation-induced cross-linking is used to enhance the wear resistance of the material, but cross-linking also restricts relative chain movement in the amorphous regions and hence decreases toughness. Equal Channel Angular Extrusion (ECAE) is proposed as a novel mechanism by which entanglements can be introduced to the polymer bulk during consolidation, with the aim of imparting the same tribological benefits of conventional processing without complete inhibition of chain motion. ECAE processing at temperatures near the crystalline melt for UHMWPE produces (1) increased entanglements compared to control materials; (2) increasing entanglements with increasing temperature; and (3) mechanical properties between values for untreated polyethylene and for cross-linked polyethylene. These results support additional research in ECAE-processed UHMWPE for joint arthroplasty applications. - Highlights: • A new processing method for ultra-high molecular weight polyethylene is introduced. • The process produces a highly entangled polyethylene material. • Entanglements are hypothesized to enhance the wear resistance of polyethylene. • This process eliminates the trade-off between mechanical and wear properties.

  9. Ultra-high vacuum target assembly for charged particle irradiations in the materials research field

    International Nuclear Information System (INIS)

    Bressers, J.; Cassanelli, G.; Cat, R. de; Kohnen, H.; Gherardi, G.

    1978-01-01

    A target assembly designed for ion irradiation and ion implantation experiments on different particle accelerators is described. It consists of a target chamber separated from the beam line by a thin metal window, thus allowing implantations to be carried out under ultra-high vacuum conditions. Homogeneous in-depth distribution of the implanted ion species is realized by rotating the target about an axis perpendicular to the ion beam (rocking). The target holder is driven by means of a stepping motor with a constant step angle and a rocking device controller containing the required rocking angle-dwell time relation. Ion beam homogeneity over a sufficiently large target area is arrived at by transforming the Gaussian beam intensity profile into a flat beam intensity distribution by means of an electrostatic ring lens. The beam intensity profile is monitored by means of a specially designed ion beam monitor based on the Nipkov disc principle. A toroidal beam current monitoring transformer continuously measures the total beam current. Beam scanners and current measuring collimators complete the beam analysing equipment

  10. Structural modifications of ultra-high molecular weight polyethylene (UHMWPE) processed in attritor type mill

    International Nuclear Information System (INIS)

    Gabriel, Melina C.; Carvalho, Benjamim de M.; Pinheiro, Luis A.; Cintho, Osvaldo M.; Capocchi, Jose D.T.; Kubaski, Evaldo T.

    2009-01-01

    Ultra-high molecular weight polyethylene (UHMWPE) is a polyethylene that has a high melt viscosity, hence its processing becomes very difficult. High-energy mechanical milling provides physical and chemical changes in polymers that have been studied recently. In order to study these changes in UHMWPE, powder of this polymer was mechanical milled in attritor type mill with a ball-to-powder weight ratio of 40:1 for 8 hours, varying the rotation speed: 200, 300, 400, 500 e 600 rpm. The polymer was characterized by scanning electron microscopy (SEM) and xray diffraction (XRD). From the XRD results it was noted that as the rotation speed increased the monoclinic phase also increased up to 500 rpm. For 600 rpm, the amount of monoclinic phase apparently decreased. At this rotation speed, the deformation rate probably increased the process temperature, allowing the monoclinic phase to return to its initial structural orthorhombic form. (author)

  11. Highly hydrophilic ultra-high molecular weight polyethylene powder and film prepared by radiation grafting of acrylic acid

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Honglong [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Xu, Lu; Li, Rong [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China); Pang, Lijuan [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Hu, Jiangtao; Wang, Mouhua [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China); Wu, Guozhong, E-mail: wuguozhong@sinap.ac.cn [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China)

    2016-09-30

    Highlights: • Hydrophilic UHMWPE powder and film were obtained by γ-ray pre-irradiation grafting of AA. • A low concentration of AA solution was used for surface modification of UHMWPE. • A small grafting yield of AA sufficiently improved hydrophilicity of UHMWPE powder and film. - Abstract: The surface properties of ultra-high molecular weight polyethylene (UHMWPE) are very important for its use in engineering or composites. In this work, hydrophilic UHMWPE powder and film were prepared by γ-ray pre-irradiation grafting of acrylic acid (AA) and further neutralization with sodium hydroxide solution. Variations in the chemical structure, grafting yield and hydrophilicity were investigated and compared. FT-IR and XPS analysis results showed that AA was successfully grafted onto UHMWPE powder and film; the powder was more suitable for the grafting reaction in 1 wt% AA solution than the film. Given a dose of 300 kGy, the grafting yield of AA was ∼5.7% for the powder but ∼0.8% for the film under identical conditions. Radiation grafting of a small amount of AA significantly improved the hydrophilicity of UHMWPE. The water contact angle of the UHMWPE-g-PAA powder with a grafting yield of AA at ∼5.7% decreased from 110.2° to 68.2°. Moreover, the grafting powder (UHMWPE-g-PAA) exhibited good dispersion ability in water.

  12. Flexible mechanoprosthesis made from woven ultra-high-molecular-weight polyethylene fibres: proof of concept in a chronic sheep model

    NARCIS (Netherlands)

    Basir, Amir; Grobben, Remco B.; Cramer, Maarten Jan; van Herwaarden, Joost A.; Vink, Aryan; Pasterkamp, Gerard; Kluin, Jolanda; Gründeman, Paul F.

    2017-01-01

    OBJECTIVES: Ultra-high-molecular-weight polyethylene (UHMWPE) fibres are flexible, have high tensile strength, and platelet and bacterial adhesion is low. Therefore, UHMWPE may overcome limitations of current mechanical valves and bioprostheses. In this study, the bio-compatibility and functionality

  13. Photoluminescence of ultra-high molecular weight polyethylene modified by fast atom bombardment

    International Nuclear Information System (INIS)

    Toth, S.; Fuele, M.; Veres, M.; Pocsik, I.; Koos, M.; Toth, A.; Ujvari, T.; Bertoti, I.

    2006-01-01

    An increase in the application potential of the ultra-high molecular weight polyethylene (UHMWPE) may be achieved by producing a hard, wear resistant carbonaceous modified surface layer on it. In this study the surface of UHMWPE samples was treated by 1 keV N, H and He fast atom bombardment (FAB) to obtain amorphous carbon surface layer which produces an enhancement of microhardness. The untreated and FAB-modified samples were investigated by photoluminescence, infrared, Raman and optical absorption spectroscopy. The FAB-treatment caused a nearly complete disappearance of the characteristic luminescence bands of UHMWPE (at 335, 351, 363 and 381 nm), the appearance of new bands at 459 and 495 nm due to the formation of new recombination levels in the FAB-treated samples. The remarkable decrease in integrated luminescence intensity indicates the appearance of new non-radiative recombination levels caused by FAB treatment. Structural modifications in FAB treated samples result in the development of structural arrangement containing sp 2 bonded carbon sites in rings or chains of different sizes and the electronic levels corresponding to these structural elements are situated in the forbidden gap in the electronic density of states which brings forth the observed changes of the photoluminescence properties

  14. Surface functionalization of solid state ultra-high molecular weight polyethylene through chemical grafting

    Science.gov (United States)

    Sherazi, Tauqir A.; Rehman, Tayyiba; Naqvi, Syed Ali Raza; Shaikh, Ahson Jabbar; Shahzad, Sohail Anjum; Abbas, Ghazanfar; Raza, Rizwan; Waseem, Amir

    2015-12-01

    The surface of ultra-high molecular weight polyethylene (UHMWPE) powder was functionalized with styrene using chemical grafting technique. The grafting process was initiated through radical generation on base polymer matrix in the solid state by sodium thiosulfate, while peroxides formed at radical sites during this process were dissociated by ceric ammonium nitrate. Various factors were optimized and reasonably high level of monomer grafting was achieved, i.e., 15.6%. The effect of different acids as additive and divinyl benzene (DVB) as a cross-linking agent was also studied. Post-grafting sulfonation was conducted to introduce the ionic moieties to the grafted polymer. Ion-exchange capacity (IEC) was measured experimentally and is found to be 1.04 meq g-1, which is in close agreement with the theoretical IEC values. The chemical structure of grafted and functionalized polymer was characterized by attenuated total reflection infrared spectroscopy (ATR-FTIR) and thermal properties were investigated by thermo gravimetric analysis (TGA) and differential scanning calorimetry (DSC). Thermal analysis depicts that the presence of radicals on the polymer chain accelerates the thermal decomposition process. The results signify that the chemical grafting is an effective tool for substantial surface modification and subsequent functionalization of polyethylene.

  15. Extrudable polymer-polymer composites based on ultra-high molecular weight polyethylene

    Science.gov (United States)

    Panin, S. V.; Kornienko, L. A.; Alexenko, V. O.; Buslovich, D. G.; Dontsov, Yu. V.

    2017-12-01

    Mechanical and tribotechnical characteristics of polymer-polymeric composites of UHMWPE are studied with the aim of developing extrudable, wear-resistant, self-lubricant polymer mixtures for Additive Manufacturing (AM). The motivation of the study is their further application as feedstocks for 3D printing. Blends of UHMWPE with graft- and block copolymers of low-density polyethylene (HDPE-g-VTMS, HDPE-g-SMA, HDPE-b-EVA), polypropylene (PP), block copolymers of polypropylene and polyamide with linear low density polyethylene (PP-b-LLDPE, PA-b-LLDPE), as well as cross-linked polyethylene (PEX-b), are examined. The choice of compatible polymer components for an ultra- high molecular weight matrix for increasing processability (extrudability) is motivated by the search for commercially available and efficient additives aimed at developing wear-resistant extrudable polymer composites for additive manufacturing. The extrudability, mechanical properties and wear resistance of UHMWPE-based polymer-polymeric composites under sliding friction with different velocities and loads are studied.

  16. The role of hydroperoxides as a precursor in the radiation-induced graft polymerization of methyl methacrylate to ultra-high molecular weight polyethylene

    Energy Technology Data Exchange (ETDEWEB)

    Enomoto, Ichiro, E-mail: enomoto.ichiro@iri-tokyo.j [Tokyo Metropolitan Industrial Technology Research Institute, KFC bldg., 12F, 1-6-1, Yokoami, Sumida-ku, Tokyo 130-0015 (Japan); School of Engineering, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan); Katsumura, Yosuke [School of Engineering, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan); Advanced Science Research Center, Japan Atomic Energy Agency, 2-4 Shirakata Shirane, Tokai-mura, Ibaraki 319-1195 (Japan); Kudo, Hisaaki [School of Engineering, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8656 (Japan); Sekiguchi, Masayuki [Tokyo Metropolitan Industrial Technology Research Institute, KFC bldg., 12F, 1-6-1, Yokoami, Sumida-ku, Tokyo 130-0015 (Japan)

    2010-06-15

    A graft polymerization of methyl methacrylate (MMA) to ultra-high molecular weight polyethylene (UHMWPE) with Co-60 gamma-ray irradiation in air at room temperature has been carried out. The grafting yields were measured as a function of the storage time (elapsed time from the end of irradiation to the start of grafting), and it was found that the yields reach at the maximum values at around several days since the end of irradiation. In order to clarify the precursor of the graft polymerization, changes of the radical yields and the carbonyl groups were measured as a function of storage time with ESR and microscopic FT-IR, respectively. From the similarities between the depth profiles of the hydroperoxide formation and the grafting products, it was concluded that the hydroperoxides can be main precursors of the grafting of the radiation-induced polymerization of MMA to UHMWPE under the given conditions.

  17. The role of hydroperoxides as a precursor in the radiation-induced graft polymerization of methyl methacrylate to ultra-high molecular weight polyethylene

    International Nuclear Information System (INIS)

    Enomoto, Ichiro; Katsumura, Yosuke; Kudo, Hisaaki; Sekiguchi, Masayuki

    2010-01-01

    A graft polymerization of methyl methacrylate (MMA) to ultra-high molecular weight polyethylene (UHMWPE) with Co-60 γ-ray irradiation in air at room temperature has been carried out. The grafting yields were measured as a function of the storage time (elapsed time from the end of irradiation to the start of grafting), and it was found that the yields reach at the maximum values at around several days since the end of irradiation. In order to clarify the precursor of the graft polymerization, changes of the radical yields and the carbonyl groups were measured as a function of storage time with ESR and microscopic FT-IR, respectively. From the similarities between the depth profiles of the hydroperoxide formation and the grafting products, it was concluded that the hydroperoxides can be main precursors of the grafting of the radiation-induced polymerization of MMA to UHMWPE under the given conditions.

  18. Experimental Platform for Ultra-high Dose Rate FLASH Irradiation of Small Animals Using a Clinical Linear Accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Schüler, Emil; Trovati, Stefania; King, Gregory; Lartey, Frederick; Rafat, Marjan; Villegas, Manuel; Praxel, A. Joe [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California (United States); Loo, Billy W., E-mail: BWLoo@stanford.edu [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California (United States); Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California (United States); Maxim, Peter G., E-mail: PMaxim@stanford.edu [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California (United States); Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California (United States)

    2017-01-01

    Purpose: A key factor limiting the effectiveness of radiation therapy is normal tissue toxicity, and recent preclinical data have shown that ultra-high dose rate irradiation (>50 Gy/s, “FLASH”) potentially mitigates this effect. However, research in this field has been strongly limited by the availability of FLASH irradiators suitable for small animal experiments. We present a simple methodologic approach for FLASH electron small animal irradiation with a clinically available linear accelerator (LINAC). Methods and Materials: We investigated the FLASH irradiation potential of a Varian Clinac 21EX in both clinical mode and after tuning of the LINAC. We performed detailed FLUKA Monte Carlo and experimental dosimetric characterization at multiple experimental locations within the LINAC head. Results: Average dose rates of ≤74 Gy/s were achieved in clinical mode, and the dose rate after tuning exceeded 900 Gy/s. We obtained 220 Gy/s at 1-cm depth for a >4-cm field size with 90% homogeneity throughout a 2-cm-thick volume. Conclusions: We present an approach for using a clinical LINAC for FLASH irradiation. We obtained dose rates exceeding 200 Gy/s after simple tuning of the LINAC, with excellent dosimetric properties for small animal experiments. This will allow for increased availability of FLASH irradiation to the general research community.

  19. Experimental Platform for Ultra-high Dose Rate FLASH Irradiation of Small Animals Using a Clinical Linear Accelerator.

    Science.gov (United States)

    Schüler, Emil; Trovati, Stefania; King, Gregory; Lartey, Frederick; Rafat, Marjan; Villegas, Manuel; Praxel, A Joe; Loo, Billy W; Maxim, Peter G

    2017-01-01

    A key factor limiting the effectiveness of radiation therapy is normal tissue toxicity, and recent preclinical data have shown that ultra-high dose rate irradiation (>50 Gy/s, "FLASH") potentially mitigates this effect. However, research in this field has been strongly limited by the availability of FLASH irradiators suitable for small animal experiments. We present a simple methodologic approach for FLASH electron small animal irradiation with a clinically available linear accelerator (LINAC). We investigated the FLASH irradiation potential of a Varian Clinac 21EX in both clinical mode and after tuning of the LINAC. We performed detailed FLUKA Monte Carlo and experimental dosimetric characterization at multiple experimental locations within the LINAC head. Average dose rates of ≤74 Gy/s were achieved in clinical mode, and the dose rate after tuning exceeded 900 Gy/s. We obtained 220 Gy/s at 1-cm depth for a >4-cm field size with 90% homogeneity throughout a 2-cm-thick volume. We present an approach for using a clinical LINAC for FLASH irradiation. We obtained dose rates exceeding 200 Gy/s after simple tuning of the LINAC, with excellent dosimetric properties for small animal experiments. This will allow for increased availability of FLASH irradiation to the general research community. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Biomechanical testing of new meniscal repair techniques containing ultra high-molecular weight polyethylene suture.

    Science.gov (United States)

    Barber, F Alan; Herbert, Morley A; Schroeder, F Alexander; Aziz-Jacobo, Jorge; Sutker, Michael J

    2009-09-01

    To evaluate the biomechanical characteristics of current meniscal repair techniques containing ultra high-molecular weight polyethylene (UHMWPE) suture with and without cyclic loading. Vertical longitudinal cuts made in porcine menisci were secured with a single repair device. Noncycled and cycled (500 cycles) biomechanical tests were performed on the following groups: group 1, No. 2-0 Mersilene vertical suture (Ethicon, Somerville, NJ); group 2, No. 2-0 Orthocord vertical suture (DePuy Mitek, Westwood, MA); group 3, No. 0 Ultrabraid vertical suture (Smith & Nephew Endoscopy, Andover, MA); group 4, No. 2-0 FiberWire vertical suture (Arthrex, Naples, FL); group 5, vertically oriented mattress suture by use of an Ultra FasT-Fix device (Smith & Nephew Endoscopy) with No. 0 Ultrabraid; group 6, vertically oriented mattress suture by use of a RapidLoc A2 device (DePuy Mitek) with No. 2-0 Orthocord suture; group 7, vertically oriented stitch by use of a MaxFire device with MaxBraid PE suture (Biomet Sports Medicine, Warsaw, IN); and group 8, an obliquely oriented stitch of No. 0 UHMWPE suture inserted by use of a CrossFix device (Cayenne Medical, Scottsdale, AZ). Endpoints were failure loads, failure modes, stiffness, and cyclic displacement. Mean single-pull loads were calculated for Ultra FasT-Fix (121 N), FiberWire (110 N), MaxFire (130 N), Mersilene (84 N), Orthocord (124 N), RapidLoc A2 (86 N), CrossFix (77 N), and Ultrabraid (109 N). After 500 cyclic loads, the Orthocord (222 N) repair was stronger than the others: Ultra FasT-Fix (110 N), FiberWire (117 N), MaxFire (132 N), Mersilene (89 N), RapidLoc A2 (108 N), CrossFix (95 N), and Ultrabraid (126 N) (P Fix, RapidLoc A2, and MaxFire) were comparable to the isolated UHMWPE-containing suture repairs on single-failure load testing. UHMWPE-containing suture repairs are stronger than braided polyester suture repairs, but pure UHMWPE suture (Ultrabraid) elongated more during cycling. Orthocord suture is significantly

  1. Molecular composition of organic aerosols in central Amazonia: an ultra-high-resolution mass spectrometry study

    OpenAIRE

    Kourtchev, I; Godoi, RHM; Connors, S; Levine, JG; Archibald, AT; Godoi, AFL; Paralovo, SL; Barbosa, CGG; Souza, RAF; Manzi, AO; Seco, R; Sjostedt, S; Park, J-H; Guenther, A; Kim, S

    2016-01-01

    The Amazon Basin plays key role in atmospheric chemistry, biodiversity and climate change. In this study we applied nanoelectrospray (nanoESI) ultra-high-resolution mass spectrometry (UHRMS) for the analysis of the organic fraction of PM$_{2.5}$ aerosol samples collected during dry and wet seasons at a site in central Amazonia receiving background air masses, biomass burning and urban pollution. Comprehensive mass spectral data evaluation methods (e.g. Kendrick mass defect, Van Krevelen diagr...

  2. Ultra high vacuum fracture and transfer device for AES analysis of irradiated austenitic stainless steel

    International Nuclear Information System (INIS)

    Urie, M.W.; Panayotou, N.F.; Robinson, J.E.

    1980-01-01

    An ultrahigh vacuum fracture and transfer device for analysis of irradiated and non-irradiated SS 316 fuel cladding is described. Mechanical property tests used to study the behavior of cladding during reactor transient over-power conditions are reported. The stress vs temperature curves show minimal differences between unirradiated cladding and unfueled cladding. The fueled cladding fails at a lower temperature. All fueled specimens failed in an intergranular mode

  3. Ballistic behaviour of ultra-high molecular weight polyethylene: effect of gamma radiation

    International Nuclear Information System (INIS)

    Alves, Andreia L.S.; Nascimento, Lucio F.C.; Miguez Suarez, Joao Carlos

    2004-01-01

    The fiber reinforced polymer matrix composites (PMCs) are considered excellent engineering materials. In structural applications, when a high strength-to-weight ratio is fundamental for the design, PMCs are successfully replacing many conventional materials. Since World War II textile materials have been used as ballistic armor. Materials manufactured with ultrahigh molecular weight polyethylene (UHMWPE) fibers are used in the production of armor materials, for personnel protection and armored vehicles. As these have been developed and commercialized more recently, there is not enough information about the action of the ionizing radiation in the ballistic performance of this armor material. In the present work the ballistic behavior of composite plates manufactured with ultrahigh molecular weight polyethylene (UHMWPE) fibers were evaluated after exposure to gamma radiation. The ballistic tests results were related to the macromolecular modifications induced by the environmental degradation through mechanical (hardness, impact and flexure) and physicochemical (infrared spectroscopy, differential scanning calorimetry and thermal gravimetric analysis) tests. Our results indicate that gamma irradiation induces modifications in the UHMWPE macromolecular chains, altering the mechanical properties of the composite and decreasing, for higher radiation doses, its ballistic performance. These results are presented and discussed. (author)

  4. Dislocation loops in ultra-high purity Fe(Cr) alloys after 7.2 MeV proton irradiation

    Science.gov (United States)

    Chen, J.; Duval, F.; Jung, P.; Schäublin, R.; Gao, N.; Barthe, M. F.

    2018-05-01

    Ultra-high purity Fe(Cr) alloys (from 0 wt% Cr to 14 wt% Cr) were 3D homogeneously irradiated by 0-7.2 MeV protons to 0.3 dpa at nominal temperatures from 270 °C to 500 °C. Microstructural changes were observed by transmission electron microscopy (TEM). The results showed that evolution of dislocation loops depends on the Cr content. Below 300 °C, large ½ a0 loops are dominating. Above 300 °C, a0 loops with a habit plane {100} appear. Loop sizes of both types are more or less the same. At temperatures from 310 °C to 400 °C, a0 loops form clusters with the same {100} habit plane as the one of the loops forming them. This indicates that loops of the same variant start gliding under mutual elastic interaction. At 500 °C, dislocation loops form disc shaped clusters about 1000 nm in diameter and sitting on {111} and/or {100} planes in the pure Fe samples. Based on these observations a quantitative analysis of the dislocation loops configurations and their temperature dependence is made, leading to an understanding of the basic mechanisms of formation of these loops.

  5. Ultra-High Molecular Weight Polyethylene: Influence of the Chemical, Physical and Mechanical Properties on the Wear Behavior. A Review

    Directory of Open Access Journals (Sweden)

    Pierangiola Bracco

    2017-07-01

    Full Text Available Ultra-high molecular weight polyethylene (UHMWPE is the most common bearing material in total joint arthroplasty due to its unique combination of superior mechanical properties and wear resistance over other polymers. A great deal of research in recent decades has focused on further improving its performances, in order to provide durable implants in young and active patients. From “historical”, gamma-air sterilized polyethylenes, to the so-called first and second generation of highly crosslinked materials, a variety of different formulations have progressively appeared in the market. This paper reviews the structure–properties relationship of these materials, with a particular emphasis on the in vitro and in vivo wear performances, through an analysis of the existing literature.

  6. A Tribological Assessment of Ultra High Molecular Weight Polyethylene Types GUR 1020 and GUR 1050 for Orthopedic Applications

    Directory of Open Access Journals (Sweden)

    Benjamin J. Hunt

    2016-06-01

    Full Text Available The wear properties of biomaterials have been demonstrated to have a high importance within orthopedic bearing surfaces. This study performed a comparison of the wear between the two main grades of Ultra High Molecular Weight Polyethylene types GUR 1020 and GUR 1050 articulating against Cobalt Chromium. Such a high capacity wear comparison has not been reported elsewhere in the scientific literature. Under an identical testing protocol it was found that GUR 1020 had a wear factor of 3.92 ± 0.55 × 10 − 6 ( mm 3 / Nm and GUR 1050 had a wear factor of 3.64 ± 0.39 × 10 − 6 ( mm 3 / Nm , with a non-statistical significant difference of p = 0.052. These wear factors correlate closely with those observed from other screening wear studies and explant analysis.

  7. The effect of chromic acid treatment on the mechanical and tribological properties of aramid fibre reinforced ultra-high molecular weight polyethylene composite

    NARCIS (Netherlands)

    Hofste, JM; Pennings, AJ; Schut, J.A.

    1998-01-01

    Surface oxidation of ultra-high molecular weight polyethylene (UHMWPE) powder has an influence on the mixing procedure of chopped fibres and UHMWPE powder. Due to this oxidation hydrogen bonds can be formed between the fibres and powder particles, leading to a more homogeneous fibre-powder mixture.

  8. Radiation grafting of various water-soluble monomers on ultra-high molecular weight polyethylene powder. Part II: Thermal, FTIR and morphological characterisation

    Energy Technology Data Exchange (ETDEWEB)

    Aydinli, Bahattin; Tincer, Teoman E-mail: teotin@metu.edu.tr

    2001-10-01

    Radiation induced grafted polyacrylic acid (PAA), polymethacrylic acid (PMAA), polyacrylamide (PAAm), poly N,N-dimethyl acrylamide (PNDAAm) and poly 1-vinyl-2 pyrrolidone (PVP) on ultra-high molecular weight polyethylene (UHMWPE) were characterised by DSC, FTIR and SEM analysis. While the effect of irradiation on pure UHMWPE was found to increase crystallinity and cause higher enthalpy of crystallisation, grafted UHMWPE powders showed lower crystallinity and enthalpy of crystallisation. In all grafted UHMWPE there existed secondary transitions corresponding to grafting polymers in the first run of DSC above 60 deg. C and they became clearer at a higher grafting level. In the second run of DSC some T{sub g} values appeared to shift to higher temperatures while some were not detected. FTIR analysis indicated the presence of water-soluble polymers in the grafted UHMWPE. The characteristic peaks of water-soluble polymers became sharper in the grafted UHMWPE. SEM analysis revealed that the grafting occurs both on fiber and microparticles of UHMWPE while flowing characteristic of powder is retained.

  9. Radiation grafting of various water-soluble monomers on ultra-high molecular weight polyethylene powder. Part II: Thermal, FTIR and morphological characterisation

    Science.gov (United States)

    Aydınlı, Bahattin; Tin c̡er, Teoman

    2001-10-01

    Radiation induced grafted polyacrylic acid (PAA), polymethacrylic acid (PMAA), polyacrylamide (PAAm), poly N,N-dimethyl acrylamide (PNDAAm) and poly 1-vinyl-2 pyrrolidone (PVP) on ultra-high molecular weight polyethylene (UHMWPE) were characterised by DSC, FTIR and SEM analysis. While the effect of irradiation on pure UHMWPE was found to increase crystallinity and cause higher enthalpy of crystallisation, grafted UHMWPE powders showed lower crystallinity and enthalpy of crystallisation. In all grafted UHMWPE there existed secondary transitions corresponding to grafting polymers in the first run of DSC above 60°C and they became clearer at a higher grafting level. In the second run of DSC some Tg values appeared to shift to higher temperatures while some were not detected. FTIR analysis indicated the presence of water-soluble polymers in the grafted UHMWPE. The characteristic peaks of water-soluble polymers became sharper in the grafted UHMWPE. SEM analysis revealed that the grafting occurs both on fiber and microparticles of UHMWPE while flowing characteristic of powder is retained.

  10. Ionizing radiation effect study by electron beam on ultra high molecular weight polyethylene virgin and recycled industrial

    International Nuclear Information System (INIS)

    Rosario, Salmo Cordeiro do

    2006-01-01

    Ultra High Molecular Weight Polyethylene (UHMWPE) is an engineering plastic which has several applications, chiefly, in specific areas of the industry and medicine. UHMWPE can be even for other applications such as: port fenders, current guide, bucket coating, silos and gutters, plugs, pulleys and surgical prosthesis. This range of applications is due to the excellent technical characteristics that this material owns, such as; high resistance to wear, high resistance to impact, anti-adherence, non toxic, excellent chemical resistance, low specific weight, easy mill processing, and high resistance to fatigue. The UHMWPE type used in this work were UTEC 3041 and UTEC 6541 of the Braskem. The recycling process of UHMWPE raised much interest, because the utilization of this raw material grew over 600% in the last decade, becoming one of the most used engineering plastics for attainment of mill processed parts after polyamide. As the utilization of this polymer in the manufacturing of parts for machinery has grown, its waste is very big, because the rest of this material is thrown out, usually not being reused. The goal of this work is to recycle the UHMWPE UTEC 3041 and study the properties of this recycled and virgin material and compare the results between both with these materials submitted to different radiation dose. (author)

  11. New titanium and titanium/hydroxyapatite coatings on ultra-high-molecular-weight polyethylene-in vitro osteoblastic performance

    International Nuclear Information System (INIS)

    Silva, M A; Lopes, M A; Santos, J D; Fernandes, M H; Gomes, P S; Vila, M; Silva, R F

    2010-01-01

    The development of optimized hip joint materials is one of the most challenging opportunities in prosthetic technologies. In current approaches, ultra-high-molecular-weight polyethylene (UHMWPE) has been a favorite material for the acetabular component and, regarding the cementless technique, several coating options may be considered to contain and stabilize bearing surfaces and establish an improved interface with bone. In this work, newly developed constructs of UHMWPE coated with either commercially pure titanium (cpTi-UHMWPE), by DC magnetron sputtering, or with commercially pure titanium and hydroxyapatite (cpTi/HA-UHMWPE), by DC/RF magnetron co-sputtering, have been prepared and biologically characterized with human bone marrow-derived osteoblastic cultures. The cpTi-UHMWPE samples allowed a high cell growth and the expression of the complete osteoblastic phenotype, with high alkaline phosphatase activity, expression of osteogenic-associated genes and evident cell-mediated mineralization of the extracellular matrix. In comparison, the cpTi/HA-UHMWPE samples reported lower cell proliferation but earlier cell-mediated matrix mineralization. Accordingly, these newly developed systems may be suitable candidates to improve the osteointegration process in arthroplastic devices; nevertheless, further biological evaluation should be conducted.

  12. Radiochemical purity of Mo and Tc solution obtained after irradiation and dissolution of Mo-100-enriched and ultra-high-purity natural Mo disks

    Energy Technology Data Exchange (ETDEWEB)

    Tkac, Peter [Argonne National Lab. (ANL), Argonne, IL (United States); Gromov, Roman [Argonne National Lab. (ANL), Argonne, IL (United States); Chemerisov, Sergey D. [Argonne National Lab. (ANL), Argonne, IL (United States); Rotsch, David A. [Argonne National Lab. (ANL), Argonne, IL (United States); Vandegrift, George F. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-09-01

    Four irradiations of ultra-high-purity natural Mo targets and one irradiation using 97.4% Mo-100-enriched material were performed. The purpose of these irradiations was to determine whether the presence of Sn stabilizer in the H2O2 used for the dissolution of sintered Mo disks can affect the radiochemical purity of the final K2MoO4 in 5M KOH solution. Results from radiochemical purity tests performed using thin-layer paper chromatography show that even 2– 3× excess of Sn-stabilized H2O2 typically used for dissolution of sintered Mo disks did not affect the radiochemical purity of the final product.

  13. Ultra high molecular weight polyethylene (UHMWPE) fiber epoxy composite hybridized with Gadolinium and Boron nanoparticles for radiation shielding

    Science.gov (United States)

    Mani, Venkat; Prasad, Narasimha S.; Kelkar, Ajit

    2016-09-01

    Deep space radiations pose a major threat to the astronauts and their spacecraft during long duration space exploration missions. The two sources of radiation that are of concern are the galactic cosmic radiation (GCR) and the short lived secondary neutron radiations that are generated as a result of fragmentation that occurs when GCR strikes target nuclei in a spacecraft. Energy loss, during the interaction of GCR and the shielding material, increases with the charge to mass ratio of the shielding material. Hydrogen with no neutron in its nucleus has the highest charge to mass ratio and is the element which is the most effective shield against GCR. Some of the polymers because of their higher hydrogen content also serve as radiation shield materials. Ultra High Molecular Weight Polyethylene (UHMWPE) fibers, apart from possessing radiation shielding properties by the virtue of the high hydrogen content, are known for extraordinary properties. An effective radiation shielding material is the one that will offer protection from GCR and impede the secondary neutron radiations resulting from the fragmentation process. Neutrons, which result from fragmentation, do not respond to the Coulombic interaction that shield against GCR. To prevent the deleterious effects of secondary neutrons, targets such as Gadolinium are required. In this paper, the radiation shielding studies that were carried out on the fabricated sandwich panels by vacuum-assisted resin transfer molding (VARTM) process are presented. VARTM is a manufacturing process used for making large composite structures by infusing resin into base materials formed with woven fabric or fiber using vacuum pressure. Using the VARTM process, the hybridization of Epoxy/UHMWPE composites with Gadolinium nanoparticles, Boron, and Boron carbide nanoparticles in the form of sandwich panels were successfully carried out. The preliminary results from neutron radiation tests show that greater than 99% shielding performance was

  14. Effect of ZnO morphology on affecting bactericidal property of ultra high molecular weight polyethylene biocomposite

    International Nuclear Information System (INIS)

    Sharma, Rajeev Kumar; Agarwal, Meenakshi; Balani, Kantesh

    2016-01-01

    Bacterial infection of implants can be controlled by selective trapping of bacteria, followed with consequent killing by targeted antibacterial agents. Herein, the role of various ZnO morphologies, viz. micro-rods (R), nanoparticles (NP), and micro-disks (D) on antibacterial efficacy of ZnO via release of Zn"2"+ and H_2O_2 is assessed, both as isolated powders and via incorporating them in cytocompatible ultra high molecular weight polyethylene (UHMWPE). Though ZnO is antibacterial, interestingly, all ZnO morphologies elicited a supportive growth of gram-negative bacteria (Escherichia coli) in culture medium (until 28–35 μg/ml). But, all ZnO morphologies did elicit bactericidal effect on gram positive bacteria (Staphylococcus aureus or Staphylococcus epidermidis) both in culture medium (for 0–2.5 μg/ml) or when incorporated (5–20 wt.%) into UHMWPE. The bactericidal mechanisms were quantified for various ZnO morphologies via: (i) H_2O_2 production, (ii) Zn"2"+ release, and (iii) the presence of surface oxygen vacancies. On one hand, where only ZnO(NP) elicited release of H_2O_2 in the absence of light, maximum Zn"2"+ release was elicited by ZnO(D). Interestingly, when ZnO is incorporated as reinforcement (5–20 wt.%), its antibacterial action against E. coli was vividly observed due to selective proliferation of bacteria only on friendly UHMWPE matrix. Hence, luring bacteria on affable UHMWPE surface can be complemented with their targeted killing by ZnO present in composite. - Highlights: • The role of ZnO morphology in affecting bactericidal mechanisms • Quantification of Zn"2"+ release, H_2O_2 production and surface oxygen vacancy defects • Inherent resistance by gram negative bacteria at lower ZnO concentrations • Containment of bacteria on polymeric surface and consequent targeted killing by ZnO

  15. The interplay of plasma treatment and gold coating and ultra-high molecular weight polyethylene: On the cytocompatibility

    Energy Technology Data Exchange (ETDEWEB)

    Novotná, Zdenka, E-mail: zdenka1.novotn@vscht.cz [Department of Solid State Engineering, University of Chemistry and Technology Prague, Prague (Czech Republic); Rimpelová, Silvie; Juřík, Petr [Department of Biochemistry and Microbiology, University of Chemistry and Technology Prague, Prague (Czech Republic); Veselý, Martin [Department of Organic Technology, University of Chemistry and Technology Prague, Prague (Czech Republic); Kolská, Zdenka [Faculty and Science, J. E. Purkinje University in Usti nad Labem, Usti nad Labem (Czech Republic); Hubáček, Tomáš [Biology Centre CAS CR, SoWa National Research Infrastructure, Ceske Budejovice (Czech Republic); Ruml, Tomáš [Department of Biochemistry and Microbiology, University of Chemistry and Technology Prague, Prague (Czech Republic); Švorčík, Václav [Department of Solid State Engineering, University of Chemistry and Technology Prague, Prague (Czech Republic)

    2017-02-01

    We have investigated the application of Ar plasma for creation of nanostructured ultra high molecular weight polyethylene (PE) surface in order to enhance adhesion of mouse embryonic fibroblasts (L929). The aim of this study was to investigate the effect of the interface between plasma-treated and gold-coated PE on adhesion and spreading of cells. The surface properties of pristine samples and its modified counterparts were studied by different experimental techniques (gravimetry, goniometry and X-ray photoelectron spectroscopy (XPS), electrokinetic analysis), which were used for characterization of treated and sputtered layers, polarity and surface chemical structure, respectively. Further, atomic force microscopy (AFM) was employed to study the surface morphology and roughness. Biological responses of cells seeded on PE samples were evaluated in terms of cell adhesion, spreading, morphology and proliferation. Detailed cell morphology and intercellular connections were followed by scanning electron microscopy (SEM). As it was expected the thickness of a deposited gold film was an increasing function of the sputtering time. Despite the fact that plasma treatment proceeded in inert plasma, oxidized degradation products were formed on the PE surface which would contribute to increased hydrophilicity (wettability) of the plasma treated polymer. The XPS method showed a decrease in carbon concentration with increasing plasma treatment. Cell adhesion measured on the interface between plasma treated and gold coated PE was inversely proportional to the thickness of a gold layer on a sample. - Highlights: • Gold-coating improved wettability of polyethylene in comparison with plasma-treatment. • Plasma-treatment increased the surface roughness while the subsequent gold-coating decreased the roughness. • Adhesion and growth of mouse embryonic fibroblasts (L929) were studied in vitro. • Low amounts of gold nanoparticles released in the medium promoted cell growth.

  16. The interplay of plasma treatment and gold coating and ultra-high molecular weight polyethylene: On the cytocompatibility

    International Nuclear Information System (INIS)

    Novotná, Zdenka; Rimpelová, Silvie; Juřík, Petr; Veselý, Martin; Kolská, Zdenka; Hubáček, Tomáš; Ruml, Tomáš; Švorčík, Václav

    2017-01-01

    We have investigated the application of Ar plasma for creation of nanostructured ultra high molecular weight polyethylene (PE) surface in order to enhance adhesion of mouse embryonic fibroblasts (L929). The aim of this study was to investigate the effect of the interface between plasma-treated and gold-coated PE on adhesion and spreading of cells. The surface properties of pristine samples and its modified counterparts were studied by different experimental techniques (gravimetry, goniometry and X-ray photoelectron spectroscopy (XPS), electrokinetic analysis), which were used for characterization of treated and sputtered layers, polarity and surface chemical structure, respectively. Further, atomic force microscopy (AFM) was employed to study the surface morphology and roughness. Biological responses of cells seeded on PE samples were evaluated in terms of cell adhesion, spreading, morphology and proliferation. Detailed cell morphology and intercellular connections were followed by scanning electron microscopy (SEM). As it was expected the thickness of a deposited gold film was an increasing function of the sputtering time. Despite the fact that plasma treatment proceeded in inert plasma, oxidized degradation products were formed on the PE surface which would contribute to increased hydrophilicity (wettability) of the plasma treated polymer. The XPS method showed a decrease in carbon concentration with increasing plasma treatment. Cell adhesion measured on the interface between plasma treated and gold coated PE was inversely proportional to the thickness of a gold layer on a sample. - Highlights: • Gold-coating improved wettability of polyethylene in comparison with plasma-treatment. • Plasma-treatment increased the surface roughness while the subsequent gold-coating decreased the roughness. • Adhesion and growth of mouse embryonic fibroblasts (L929) were studied in vitro. • Low amounts of gold nanoparticles released in the medium promoted cell growth.

  17. Formation and stability of .beta.-structure in biodegradable ultra-high-molecular-weight poly(3-hydroxybutyrate) by infrared, Raman, and quantum chemical calculation studies

    Czech Academy of Sciences Publication Activity Database

    Murakami, R.; Sato, H.; Dybal, Jiří; Iwata, T.; Ozaki, Y.

    2007-01-01

    Roč. 48, č. 9 (2007), s. 2672-2680 ISSN 0032-3861 R&D Projects: GA ČR GA203/05/0425 Grant - others:Ministry of Education, Culture, Sports, Science and Technology(JP) 18750107 Institutional research plan: CEZ:AV0Z40500505 Keywords : ultra-high-molecular-weight poly(hydroxybutyrate) * .beta.-form * Raman spectroscopy Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 3.065, year: 2007

  18. Wear resistant performance of highly cross-linked and annealed ultra-high molecular weight polyethylene against ceramic heads in total hip arthroplasty.

    Science.gov (United States)

    Sato, Taishi; Nakashima, Yasuharu; Akiyama, Mio; Yamamoto, Takuaki; Mawatari, Taro; Itokawa, Takashi; Ohishi, Masanobu; Motomura, Goro; Hirata, Masanobu; Iwamoto, Yukihide

    2012-12-01

    The purpose of this study was to examine the effects of ceramic femoral head material, size, and implantation periods on the wear of annealed, cross-linked ultra-high molecular weight polyethylene (UHMWPE) (XLPE) in total hip arthroplasty compared to non-cross-linked conventional UHMWPE (CPE). XLPE was fabricated by cross-linking with 60 kGy irradiation and annealing. Femoral heads made from zirconia and alumina ceramics and cobalt-chrome (CoCr) of 22 or 26 mm diameter were used. In this retrospective cohort study, the femoral head penetration into the cup was measured digitally on radiographs of 367 hips with XLPE and 64 hips with CPE. The average follow-up periods were 6.3 and 11.9 years, respectively. Both XLPE creep and wear rates were significantly lower than those of CPE (0.19 mm vs. 0.44 mm, 0.0001 mm/year vs. 0.09 mm/year, respectively). Zirconia displayed increased wear rates compared to alumina in CPE; however, there was no difference among head materials in XLPE (0.0008, 0.00007, and -0.009 mm/year for zirconia, alumina, and CoCr, respectively). Neither head size or implantation period impacted XLPE wear. In contrast to CPE, XLPE displayed low wear rates surpassing the effects of varying femoral head material, size, implantation period, and patient demographics. Further follow-up is required to determine the long-term clinical performance of the annealed XLPE. Copyright © 2012 Orthopaedic Research Society.

  19. Effect of ZnO morphology on affecting bactericidal property of ultra high molecular weight polyethylene biocomposite

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, Rajeev Kumar [Biomaterials Processing and Characterization Laboratory, Indian Institute of Technology Kanpur, Kanpur -208016 (India); Agarwal, Meenakshi [Amity Institute of Nanotechnology, Amity University, Noida, Uttar Pradesh - 201303 (India); Balani, Kantesh, E-mail: kbalani@iitk.ac.in [Biomaterials Processing and Characterization Laboratory, Indian Institute of Technology Kanpur, Kanpur -208016 (India)

    2016-05-01

    Bacterial infection of implants can be controlled by selective trapping of bacteria, followed with consequent killing by targeted antibacterial agents. Herein, the role of various ZnO morphologies, viz. micro-rods (R), nanoparticles (NP), and micro-disks (D) on antibacterial efficacy of ZnO via release of Zn{sup 2+} and H{sub 2}O{sub 2} is assessed, both as isolated powders and via incorporating them in cytocompatible ultra high molecular weight polyethylene (UHMWPE). Though ZnO is antibacterial, interestingly, all ZnO morphologies elicited a supportive growth of gram-negative bacteria (Escherichia coli) in culture medium (until 28–35 μg/ml). But, all ZnO morphologies did elicit bactericidal effect on gram positive bacteria (Staphylococcus aureus or Staphylococcus epidermidis) both in culture medium (for 0–2.5 μg/ml) or when incorporated (5–20 wt.%) into UHMWPE. The bactericidal mechanisms were quantified for various ZnO morphologies via: (i) H{sub 2}O{sub 2} production, (ii) Zn{sup 2+} release, and (iii) the presence of surface oxygen vacancies. On one hand, where only ZnO(NP) elicited release of H{sub 2}O{sub 2} in the absence of light, maximum Zn{sup 2+} release was elicited by ZnO(D). Interestingly, when ZnO is incorporated as reinforcement (5–20 wt.%), its antibacterial action against E. coli was vividly observed due to selective proliferation of bacteria only on friendly UHMWPE matrix. Hence, luring bacteria on affable UHMWPE surface can be complemented with their targeted killing by ZnO present in composite. - Highlights: • The role of ZnO morphology in affecting bactericidal mechanisms • Quantification of Zn{sup 2+} release, H{sub 2}O{sub 2} production and surface oxygen vacancy defects • Inherent resistance by gram negative bacteria at lower ZnO concentrations • Containment of bacteria on polymeric surface and consequent targeted killing by ZnO.

  20. Mechanistic and morphological origins of ultra-high molecular weight polyethylene wear debris in total joint replacement prostheses.

    Science.gov (United States)

    Wang, A; Stark, C; Dumbleton, J H

    1996-01-01

    The mechanistic and morphological origins of microscopic wear debris generated from UHMWPE articular surfaces in total joint replacement prostheses are investigated in this study. It was found experimentally that the molecular chain structure at the articulating surface of UHMWPE undergoes a re-organization process due to strain accumulation caused by surface traction. This molecular re-organization process creates a fibre-like surface texture that exhibits an anisotropic behaviour similar to a unidirectionally reinforced polymer composite. This composite responds to stresses favourably if loaded along the fibre axis but unfavourably if loaded off axis. Due to the very complex multi-axial motion/loading nature at the articular surfaces in total joint replacements, the stress tensors applied to each localized asperity contact area continuously change their directions and magnitudes. These changes in the localized stress field create an off-axis loading situation at each localized contact zone with respect to the orientation of the molecular chains. Depending on the off-axis angle, failure of the molecular structure occurs in three different ways: tensile rupture at very small off-axis angles, shear rupture at intermediate off-axis angles and transverse splitting at large off-axis angles. These failure mechanisms all produce similar fibre-like wear debris. However, the failure stresses differ significantly among the three modes. According to this molecular wear theory, the preferred polymer microstructure for optimal wear resistance would be a three-dimensionally strong network connected by covalent bonds between molecular chains. For UHMWPE, a three-dimensional molecular network can be created by radiation induced cross-linking. Experiments conducted on both gamma irradiated and unirradiated UHMWPE specimens using a linear wear machine and multi-axial joint simulators confirmed the validity of the molecular wear theory.

  1. The use of potassium dichromate for ultra high dose up to 120 kGy measurements in industrial irradiation process

    International Nuclear Information System (INIS)

    Conceicao, Cirilo C.S.

    2009-01-01

    The purpose of this work is the study of radiation-induced reduction of the Potassium Dichromate dosimeter in perchloric acid using modification in the composition of Dichromate dosimeter proposed by Sharpe (NPL, October 1982) to extend dose limit up to 120 kGy. This modification can allow measuring dose in process of irradiation of gem and cork directly, in these processes that the absorbed doses are very high. The dosimeter study reached linear response between 10 to 120 kGy. This dosimeter was traceable to the international metrology system, using Gammacell calibrated by Fricke reference dosimeter. The evaluation of the doses was done by spectrophotometric method. Compared to the costs using PMMA (perpex dosimeters), the use of dichromate dosimeters can reduce up to 70% of the dosimetry costs in Brazil. (author)

  2. Molecular characterization of water soluble organic nitrogen in marine rainwater by ultra-high resolution electrospray ionization mass spectrometry

    Directory of Open Access Journals (Sweden)

    K. E. Altieri

    2012-04-01

    Full Text Available Atmospheric water soluble organic nitrogen (WSON is a subset of the complex organic matter in aerosols and rainwater, which impacts cloud condensation processes and aerosol chemical and optical properties and may play a significant role in the biogeochemical cycle of N. However, its sources, composition, connections to inorganic N, and variability are largely unknown. Rainwater samples were collected on the island of Bermuda (32.27° N, 64.87° W, which experiences both anthropogenic and marine influenced air masses. Samples were analyzed by ultra-high resolution electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry to chemically characterize the WSON. Elemental compositions of 2281 N containing compounds were determined over the mass range m/z+ 50 to 500. The five compound classes with the largest number of elemental formulas identified, in order from the highest number of formulas to the lowest, contained carbon, hydrogen, oxygen, and nitrogen (CHON+, CHON compounds that contained sulfur (CHONS+, CHON compounds that contained phosphorus (CHONP+, CHON compounds that contained both sulfur and phosphorus (CHONSP+, and compounds that contained only carbon, hydrogen, and nitrogen (CHN+. Compared to rainwater collected in the continental USA, average O:C ratios of all N containing compound classes were lower in the marine samples whereas double bond equivalent values were higher, suggesting a reduced role of secondary formation mechanisms. Despite their prevalence in continental rainwater, no organonitrates or nitrooxy-organosulfates were detected, but there was an increased presence of organic S and organic P containing compounds in the marine rainwater. Cluster analysis showed a clear chemical distinction between samples collected during the cold season (October to March which have anthropogenic air mass origins and samples collected during the warm season (April to September with remote

  3. Ultra high resolution tomography

    Energy Technology Data Exchange (ETDEWEB)

    Haddad, W.S.

    1994-11-15

    Recent work and results on ultra high resolution three dimensional imaging with soft x-rays will be presented. This work is aimed at determining microscopic three dimensional structure of biological and material specimens. Three dimensional reconstructed images of a microscopic test object will be presented; the reconstruction has a resolution on the order of 1000 A in all three dimensions. Preliminary work with biological samples will also be shown, and the experimental and numerical methods used will be discussed.

  4. Wear of ultra-high molecular weight polyethylene against damaged and undamaged stainless steel and diamond-like carbon-coated counterfaces.

    Science.gov (United States)

    Firkins, P; Hailey, J L; Fisher, J; Lettington, A H; Butter, R

    1998-10-01

    The wear of ultra-high molecular weight polyethylene (UHMWPE) in artificial joints and the resulting wear debris-induced osteolysis remains a major clinical concern in the orthopaedic sector. Third-body damage of metallic femoral heads is often cited as a cause of accelerated polyethylene wear, and the use of ceramic femoral heads in the hip is gaining increasing favour. In the knee prostheses and for smaller diameter femoral heads, the application of hard surface coatings, such as diamond-like carbon, is receiving considerable attention. However, to date, there has been little or no investigation of the tribology of these coatings in simulated biological environments. In this study, diamond-like carbon (DLC) has been compared to stainless steel in its undamaged form and following simulated third-body damage. The wear of UHMWPE was found to be similar when sliding against undamaged DLC and stainless steel counterfaces. DLC was found to be much more damage resistant than DLC. Under test conditions that simulate third-body damage to the femoral head, the wear of UHMWPE was seven times lower against DLC than against stainless steel (P < 0.05). The study shows DLC has considerable potential as a femoral bearing surface in artificial joints.

  5. Characterization of the mechanical properties of a new grade of ultra high molecular weight polyethylene and modeling with the viscoplasticity based on overstress.

    Science.gov (United States)

    Khan, Fazeel; Yeakle, Colin; Gomaa, Said

    2012-02-01

    Enhancements to the service life and performance of orthopedic implants used in total knee and hip replacement procedures can be achieved through optimization of design and the development of superior biocompatible polymeric materials. The introduction of a new or modified polymer must, naturally, be preceded by a rigorous testing program. This paper presents the assessment of the mechanical properties of a new filled grade of ultra high molecular weight polyethylene (UHMWPE) designated AOX(TM) and developed by DePuy Orthopaedics Inc. The deformation behavior was investigated through a series of tensile and compressive tests including strain rate sensitivity, creep, relaxation, and recovery. The polymer was found to exhibit rate-reversal behavior for certain loading histories: strain rate during creep with a compressive stress can be negative, positive, or change between the two during a test. Analogous behavior occurs during relaxation as well. This behavior lies beyond the realm of most numerical models used to computationally investigate and improve part geometry through finite element analysis of components. To address this shortcoming, the viscoplasticity theory based on overstress (VBO) has been suitably modified to capture these trends. VBO is a state variable based model in a differential formulation. Numerical simulation and prediction of all of the aforementioned tests, including good reproduction of the rate reversal behavior, is presented in this study. Copyright © 2011 Elsevier Ltd. All rights reserved.

  6. Influence of the graphite type in the mechanical properties of graphene nanosheets and ultra high molecular weight polyethylene (GN/UHMWPE) nanocomposites

    International Nuclear Information System (INIS)

    Lima, M.E. de A.; Coutinho, S.V.; Fim, F. de C.

    2016-01-01

    This paper studies the mechanical properties of graphene nanosheets and ultra high molecular weight polyethylene (GN/UHMWPE) nanocomposites. The graphene nanosheets were obtained by two methods: the first, from Graphite Micrograf HC11 after 8 hours in a ultrasound bath in 70% alcoholic solution; the second, from Graflake 9950 prepared by oxidizing with H 2 SO 4 /HNO 3 (4:1), followed by thermal expansion at 1050°C for 30 seconds and ultrasound bath for 20 hours. Both were oven dried for 24 hours at 110°C and subsequently added to the polymer in percentages of 0.5, 1.0 and 1.5% (w/w). The powders of the nanocomposites were mixed in a ball mill for 1 hour and molded by hot compression. XRD and SEM images was possible to verify that the Graflake's GN had higher delamination that the Micrograph's GN. The mechanical properties were affected in different percentages for each graphite type. (author)

  7. Mechanical, Rheological, and Bioactivity Properties of Ultra High-Molecular-Weight Polyethylene Bioactive Composites Containing Polyethylene Glycol and Hydroxyapatite

    Directory of Open Access Journals (Sweden)

    Mazatusziha Ahmad

    2012-01-01

    Full Text Available Ultrahigh-molecular-weight polyethylene/high-density polyethylene (UHMWPE/HDPE blends prepared using polyethylene glycol PEG as the processing aid and hydroxyapatite (HA as the reinforcing filler were found to be highly processable using conventional melt blending technique. It was demonstrated that PEG reduced the melt viscosity of UHMWPE/HDPE blend significantly, thus improving the extrudability. The mechanical and bioactive properties were improved with incorporation of HA. Inclusion of HA from 10 to 50 phr resulted in a progressive increase in flexural strength and modulus of the composites. The strength increment is due to the improvement on surface contact between the irregular shape of HA and polymer matrix by formation of mechanical interlock. The HA particles were homogenously distributed even at higher percentage showed improvement in wetting ability between the polymer matrix and HA. The inclusion of HA enhanced the bioactivity properties of the composite by the formation of calcium phosphate (Ca-P precipitates on the composite surface as proven from SEM and XRD analysis.

  8. Comparison of novel ultra-high molecular weight polyethylene tape versus conventional metal wire for sublaminar segmental fixation in the treatment of adolescent idiopathic scoliosis.

    Science.gov (United States)

    Takahata, Masahiko; Ito, Manabu; Abumi, Kuniyoshi; Kotani, Yoshihisa; Sudo, Hideki; Ohshima, Shigeki; Minami, Akio

    2007-08-01

    Retrospective study. To compare the surgical outcomes of posterior translational correction and fusion using hybrid instrumentation systems with either sublaminar Nesplon tape or sublaminar metal wire to treat adolescent idiopathic scoliosis (AIS). Nesplon tape, which consists of a thread of ultra-high molecular weight polyethylene fibers, has advantages over metal wire: (1) its soft and flexible properties avoid neural damage and (2) its flat configuration avoids focal distribution of the stresses to lamina; however, the efficacy of Nesplon tape in the correction of spinal deformity is as yet, still unclear. Thirty AIS patients at a single institution underwent posterior correction and fusion using hybrid instrumentation containing hook, pedicle screw, and either sublaminar polyethylene taping (15) or sublaminar metal wiring (15). Patients were evaluated preoperatively, immediately after surgery, and at a 2-year follow-up according to the radiographic changes in curve correction, operating time, intraoperative blood loss, complications, and the Scoliosis Research Society patient questionnaire (SRS-24) score. The average correction rate was 63.0% in the Nesplon tape group and 59.9% in the metal wire group immediately after surgery (P = 0.62). Fusion was obtained in all the patients without significant correction loss in both groups. There was no significant difference in operative time, intraoperative blood loss, and postoperative SRS-24 scores between the 2 groups. Complications were superficial skin infection in a single patient in the Nesplon tape group, and transient sensory disturbance in 1 patient and temporal superior mesenteric artery syndrome in another patient in the metal wire group. The efficacy of Nesplon tape in correction of deformity is equivalent to that of metal wire, and fusion was completed without significant correction loss. The soft and flexible properties and flat configuration of Nesplon tape make this a safe application for the treatment

  9. Plasma parameters effects on the properties, aging and stability behaviors of allylamine plasma coated ultra-high molecular weight polyethylene (UHMWPE) films

    Energy Technology Data Exchange (ETDEWEB)

    Aziz, Gaelle, E-mail: gaelle.aziz@ugent.be; Thukkaram, Monica; De Geyter, Nathalie; Morent, Rino

    2017-07-01

    Highlights: • Medium to atmospheric pressure DBD is used to deposit amino rich films. • Process parameters affect the films’ surface chemical and physical properties. • High deposition rates can be reached by varying the power and/or monomer flow rate. • High amino selectivity (NH{sub 2}/N in %) is obtained at low powers and high monomer concentration. • Aging and stability behaviors of the deposited coatings can be controlled by carefully choosing the plasma parameters. - Abstract: In this work, a dielectric barrier discharge (DBD) operated at medium to atmospheric pressure has been used for the deposition of thin polyallylamine (PAA) films on ultra-high molecular weight polyethylene (UHMWPE) substrates. The effect of treatment time (1–5 min), discharge power (5.7–24.0 W), monomer concentration (1–2 g/h) and pressure (10–100 kPa) on the films properties, aging and stability behaviors have been investigated. The used characterization techniques are X-ray photoelectron spectroscopy, water contact angle and optical reflectance spectroscopy. In this paper, it is shown that plasma treatment time does not affect the coatings chemistry; whereas plasma power, monomer concentration and pressure control the coatings properties. It is also shown that the deposition rate of the deposited films changes with varying W/FM values. At low W/FM values, high deposition rates of up to 2 nm/s are observed. Plasma treatments were also characterized by their amino efficiency ([NH{sub 2}]/[C] in %) and amino selectivity ([NH{sub 2}]/[N] in %). Depending on the used parameters, these varied between 12.3% and 20% and between 71.2% and 91.1%, respectively. For the aging study, coatings that preserved most of their hydrophilicity were obtained at power ≤11.3 W, monomer concentration ≥1.5 g/h and pressure ≥50 kPa. For the stability study, coatings that showed the highest [N] (%) and lowest percentage of thickness decrease were obtained at ≤2 min, 24.0 W, 1 g/h and

  10. Surface modification of vascular endothelial growth factor-loaded silk fibroin to improve biological performance of ultra-high-molecular-weight polyethylene via promoting angiogenesis

    Directory of Open Access Journals (Sweden)

    Ai C

    2017-10-01

    Full Text Available Chengchong Ai, Dandan Sheng, Jun Chen, Jiangyu Cai, Siheng Wang, Jia Jiang, Shiyi Chen Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, People’s Republic of China Abstract: Ultra-high-molecular-weight polyethylene (UHMWPE has been applied in orthopedics, as the materials of joint prosthesis, artificial ligaments, and sutures due to its advantages such as high tensile strength, good wear resistance, and chemical stability. However, postoperative osteolysis induced by UHMWPE wear particles and poor bone–implant healing interface due to scarcity of osseointegration is a significant problem and should be solved imperatively. In order to enhance its affinity to bone tissue, vascular endothelial growth factor (VEGF was loaded on the surface of materials, the loading was performed by silk fibroin (SF coating to achieve a controlled-release delivery. Several techniques including field emission scanning electron microscopy (FESEM and attenuated total reflectance (ATR-Fourier transform infrared (FTIR and water contact angle measurement were used to validate the effectiveness of introduction of SF/VEGF. The result of ELISA demonstrated that the release of VEGF was well maintained up to 4 weeks. The modified UHMWPE was evaluated by both in vitro and in vivo experiments. According to the results of FESEM and cell counting kit-8 (CCK-8 assay, bone marrow mesenchymal stem cells cultured on the UHMWPE coated with SF/VEGF and SF exhibited a better proliferation performance than that of the pristine UHMWPE. The model rabbit of anterior cruciate ligament reconstruction was used to observe the graft–bone healing process in vivo. The results of histological evaluation, microcomputed tomography (micro-CT analysis, and biomechanical tests performed at 6 and 12 weeks after surgery demonstrated that graft–bone healing could be significantly improved due to the effect of VEGF on angiogenesis, which was loaded on the surface by SF

  11. Molecular dynamics for irradiation driven chemistry

    DEFF Research Database (Denmark)

    Sushko, Gennady B.; Solov'yov, Ilia A.; Solov'yov, Andrey V.

    2016-01-01

    A new molecular dynamics (MD) approach for computer simulations of irradiation driven chemical transformations of complex molecular systems is suggested. The approach is based on the fact that irradiation induced quantum transformations can often be treated as random, fast and local processes...... that describe the classical MD of complex molecular systems under irradiation. The proposed irradiation driven molecular dynamics (IDMD) methodology is designed for the molecular level description of the irradiation driven chemistry. The IDMD approach is implemented into the MBN Explorer software package...... involving small molecules or molecular fragments. We advocate that the quantum transformations, such as molecular bond breaks, creation and annihilation of dangling bonds, electronic charge redistributions, changes in molecular topologies, etc., could be incorporated locally into the molecular force fields...

  12. Ultra high energy cosmic rays

    International Nuclear Information System (INIS)

    Watson, A.A.

    1986-01-01

    Cosmic radiation was discovered 70 years ago but its origin remains an open question. The background to this problem is outlined and attempts to discover the origin of the most energetic and rarest group above 10 15 eV are described. Measurements of the energy spectrum and arrival direction pattern of the very highest energy particles, mean energy about 6 x 10 19 eV, are used to argue that these particles originate outside our galaxy. Recent evidence from the new field of ultra high energy γ-ray astronomy are discussed in the context of a galactic origin hypothesis for lower energy cosmic rays. (author)

  13. Ultra-high resolution protein crystallography

    International Nuclear Information System (INIS)

    Takeda, Kazuki; Hirano, Yu; Miki, Kunio

    2010-01-01

    Many protein structures have been determined by X-ray crystallography and deposited with the Protein Data Bank. However, these structures at usual resolution (1.5< d<3.0 A) are insufficient in their precision and quantity for elucidating the molecular mechanism of protein functions directly from structural information. Several studies at ultra-high resolution (d<0.8 A) have been performed with synchrotron radiation in the last decade. The highest resolution of the protein crystals was achieved at 0.54 A resolution for a small protein, crambin. In such high resolution crystals, almost all of hydrogen atoms of proteins and some hydrogen atoms of bound water molecules are experimentally observed. In addition, outer-shell electrons of proteins can be analyzed by the multipole refinement procedure. However, the influence of X-rays should be precisely estimated in order to derive meaningful information from the crystallographic results. In this review, we summarize refinement procedures, current status and perspectives for ultra high resolution protein crystallography. (author)

  14. The effect of radiation dose on the crosslink density of ultra-high molecular weight polyethylene (UHMWPE) measured by a novel swelling method

    International Nuclear Information System (INIS)

    Muratoglu, O.K.; Bragdon, C.R.; O'Connor, D.O.; Jasty, M.; Harris, W.H.

    1998-01-01

    The crosslink density of a polyethylene network structure can be determined by swelling in hot xylene (130 deg C). The Flory's swelling theory is generally used to calculate the crosslink density, dx (ln(l-q -1 )+q -1 +Xq -1 )/(V 1 q -1/3 ), where V 1 is the molar volume of xylene at 130 deg C (136 cc/mol), X is the xylene-polyethylene interaction parameter, and q is the equilibrium volume swelling ratio of cross-linked network in hot xylene. Conventionally, q is measured using gravimetric methods as described in ASTM D2765-95. However, as noted in the ASTM standard, the gravimetric method has a large error factor associated with the measurement of q (as much as 100%). UHMWPE was irradiated (range of 25 to 300 kGy) using an AECL I 10/1 linear electron beam accelerator operated at 1 kW. The irradiated specimens were subsequently melt-annealed at 150 deg C for 2 hours in vacuum. For swelling experiments, 2 mm thin samples were machined using a diamond blade. The sample sizes were kept at around 3x3x2 mm and the bottom and top surfaces were machined parallel to each other. The equilibrium volume swelling ratios were determined using a Perkin-Elmer TMA/DMA 7 (n=3 for each radiation dose level). The samples were placed in a quartz basket-probe assembly and lowered into a xylene/antioxidant bath at room temperature. The xylene was then heated to 130 deg C at 5 deg C/min and held at 130 deg C for 2 hours. The swelling was then recorded with the upward motion of the probe until the equilibrium swelling was achieved. (The experiments were carried out in 3 orthogonal directions which confirmed the isotropy of swelling). (author)

  15. The effect of radiation dose on the crosslink density of ultra-high molecular weight polyethylene (UHMWPE) measured by a novel swelling method

    International Nuclear Information System (INIS)

    Muratoglu, O.K.; Bragdon, C.R.; O'Connor, D.O.; Jasty, M.; Harris, W.H.

    1998-01-01

    The crosslink density of a polyethylene network structure can be determined by swelling in hot xylene (130 deg C). The Flory's swelling theory is generally used to calculate the crosslink density, dx (ln(l-q -1 ) + q -1 + Xq -1 )/(V l q -1/3 ), where V l is the molar volume of xylene at 130 deg C (136 cc/mol), X is the xylene-polyethylene interaction parameter, and q is the equilibrium volume swelling ratio of cross-linked network in hot xylene. Conventionally, q is measured using gravimetric methods as described in ASTM D2765-95. However, as noted in the ASTM standard, the gravimetric method has a large error factor associated with the measurement of q (as much as 100%). UHMWPE was irradiated (range of 25 to 300 kGy) using an AECL I 10/1 linear electron beam accelerator operated at 1 kW. The irradiated specimens were subsequently melt-annealed at 150 deg C for 2 hours in vacuum. For swelling experiments, 2 mm thin samples were machined using a diamond blade. The sample sizes were kept at around 3x3x2 mm and the bottom and top surfaces were machined parallel to each other. The equilibrium volume swelling ratios were determined using a Perkin-Elmer TMA/DMA 7 (n=3 for each radiation dose level). The samples were placed in a quartz basket-probe assembly and lowered into a xylene/antioxidant bath at room temperature. The xylene was then heated to 130 deg C at 5 deg C/min and held at 130 deg C for 2 hours. The swelling was then recorded with the upward motion of the probe until the equilibrium swelling was achieved. (The experiments were carried out in 3 orthogonal directions which confirmed the isotropy of swelling). From this one-dimensional change in height, q was calculated by taking into account the volumetric expansion due to heating and melting. (author)

  16. Gelation of Photonic Microdomain Structures Formed in Semi-Dilute Solutions of Ultra-High-Molecular-Weight Polystyrene-b-Polybutadiene with Various Polybutadiene Contents

    International Nuclear Information System (INIS)

    Okamoto, S; Ito, S; Ando, K; Mouri, M; Ikeda, A; Hasegawa, H; Koshikawa, N

    2010-01-01

    Well-ordered microdomain structures were obtained in semi-dilute solutions and successfully stabilized by gelation. We used polystyrene-b-polybutadiene (PS-b-PB) diblock copolymer with the weight-averaged molecular weight varying from several hundred thousands to millions g/mol. The solutions had iridescent colors because the domain spacing is on the order of the wavelength of visible light. As the structures are susceptible to distortion by flow or vibration, structural fixation was carried out by gelation. The polybutadiene used has the microstructure of 1,2-linkage and hence the chains can be cross-linkable. The Small-Angle X-ray Scattering and the UV-vis spectroscopic measurements showed that in the case of PS-b-PBs with the PB volume fraction, φ PB , greater than about 50 vol % the microdomain structures were successfully fixed by gelation, while largely distorted in the case of those with φ PB < ca. 50 vol %. The SAXS scattering intensities were quantitatively analyzed by the scattering functions numerically calculated based on the one- and two-dimensional paracrystal theories and on the concentration fluctuation between the polymers and the solvent molecules.

  17. Ultra high energy gamma-ray astronomy

    International Nuclear Information System (INIS)

    Wdowczyk, J.

    1986-01-01

    The experimental data on ultra high energy γ-rays are reviewed and a comparison of the properties of photon and proton initiated shower is made. The consequences of the existence of the strong ultra high energy γ-ray sources for other observations is analysed and possible mechanisms for the production of ultra high energy γ-rays in the sources are discussed. It is demonstrated that if the γ-rays are produced via cosmic ray interactions the sources have to produce very high fluxes of cosmic ray particles. In fact it is possible that a small number of such sources can supply the whole Galactic cosmic ray flux

  18. Sintering of ultra high molecular weight polyethylene

    Indian Academy of Sciences (India)

    Unknown

    coefficient of friction, good abrasion resistance, good chemical resistance etc. It is used in ... mainly used in electrical industries, shipbuilding, coal and mining, textile ... particles deformed leading to decrease in porosity and increase in density.

  19. Ultra-high temperature direct propulsion

    International Nuclear Information System (INIS)

    Araj, K.J.; Slovik, G.; Powell, J.R.; Ludewig, H.

    1987-01-01

    Potential advantages of ultra-high exhaust temperature (3000 K - 4000 K) direct propulsion nuclear rockets are explored. Modifications to the Particle Bed Reactor (PBR) to achieve these temperatures are described. Benefits of ultra-high temperature propulsion are discussed for two missions - orbit transfer (ΔV = 5546 m/s) and interplanetary exploration (ΔV = 20000 m/s). For such missions ultra-high temperatures appear to be worth the additional complexity. Thrust levels are reduced substantially for a given power level, due to the higher enthalpy caused by partial disassociation of the hydrogen propellant. Though technically challenging, it appears potentially feasible to achieve such ultra high temperatures using the PBR

  20. Modification of Ultra-High Vacuum Surfaces Using Free Radicals

    CERN Document Server

    Vorlaufer, G

    2002-01-01

    In ultra-high vacuum systems outgassing from vacuum chamber walls and desorption of surface adsorbates are usually the factors which determine pressure and residual gas composition. In particular in beam vacuum systems of accelerators like the LHC, where surfaces are exposed to intense synchrotron radiation and bombardment by energetic ions and electrons, surface properties like the molecular desorption yield or secondary electron yield can strongly influence the performance of the accelerator. Well-established treatment methods like vacuum bake-out or glow-discharge cleaning have been successfully applied in the past to condition ultra-high vacuum surfaces, but these methods are sometimes difficult to carry out, for example if the vacuum chambers are not accessible. In this work, an alternative treatment method is investigated. This method is based on the strong chemical reactivity of free radicals, electrically neutral fragments of molecules. Free radicals (in the case of this work, nitrogen and oxygen radi...

  1. Irradiated aromatic polysulphones of increased flow resistance and molecular weight

    International Nuclear Information System (INIS)

    Staniland, P.A.; Jarrett, W.G.

    1976-01-01

    Aromatic polymers of increased resistance to flow and molecular weight are obtained by irradiation using β-rays or γ-rays at temperatures up to 400 0 C of an aromatic polymer whose molecular chains comprise benzenoid groups and bivalent linking groups, and where irradiation is γ-rays by heating subsequent to irradiation at 200 to 400 0 C

  2. Comportamento balístico de compósito de polietileno de altíssimo peso molecular: efeito da radiação gama Ballistic behaviour of ultra-high molecular weight polyethylene: effect of gamma radiation

    Directory of Open Access Journals (Sweden)

    Andreia L. S. Alves

    2004-06-01

    polyethylene (UHMWPE fibers are used in the production of armor materials, for personnel protection and armored vehicles. As these have been developed and commercialized more recently, there is not enough information about the action of the ionizing radiation in the ballistic performance of this armor material. In the present work the ballistic behavior of composite plates manufactured with ultrahigh molecular weight polyethylene (UHMWPE fibers were evaluated after exposure to gamma radiation. The ballistic tests results were related to the macromolecular modifications induced by the environmental degradation through mechanical (hardness, impact and flexure and physicochemical (infrared spectroscopy, differential scanning calorimetry and thermal gravimetric analysis tests. Our results indicate that gamma irradiation induces modifications in the UHMWPE macromolecular chains, altering the mechanical properties of the composite and decreasing, for higher radiation doses, its ballistic performance. These results are presented and discussed.

  3. Ultra high-energy cosmic ray composition

    International Nuclear Information System (INIS)

    Longley, N.P.

    1993-01-01

    The Soudan 2 surface-underground cosmic ray experiment can simultaneously measure surface shower size, underground muon multiplicity, and underground muon separation for ultra high energy cosmic ray showers. These measurements are sensitive to the primary composition. Analysis for energies from 10 1 to 10 4 TeV favors a light flux consisting of predominantly H and He nuclei

  4. Expectations for ultra-high energy interactions

    International Nuclear Information System (INIS)

    Feynman, R.P.

    1978-01-01

    Strong interactions at ultra-high energies are discussed with emphasis on the hadrons produced in high energy collisions. Evidence is considered that quantum chromodynamics might be the right theory, and also some estimates are given of quantum chromodynamics asymptotic-freedom phenomena, the work under discussion being very preliminary. 6 references

  5. Amorphous molecular junctions produced by ion irradiation on carbon nanotubes

    International Nuclear Information System (INIS)

    Wang Zhenxia; Yu Liping; Zhang Wei; Ding Yinfeng; Li Yulan; Han Jiaguang; Zhu Zhiyuan; Xu Hongjie; He Guowei; Chen Yi; Hu Gang

    2004-01-01

    Experiments and molecular dynamics have demonstrated that electron irradiation could create molecular junctions between crossed single-wall carbon nanotubes. Recently molecular dynamics computation predicted that ion irradiation could also join single-walled carbon nanotubes. Employing carbon ion irradiation on multi-walled carbon nanotubes, we find that these nanotubes evolve into amorphous carbon nanowires, more importantly, during the process of which various molecular junctions of amorphous nanowires are formed by welding from crossed carbon nanotubes. It demonstrates that ion-beam irradiation could be an effective way not only for the welding of nanotubes but also for the formation of nanowire junctions

  6. Scaling violations at ultra-high energies

    International Nuclear Information System (INIS)

    Tung, W.K.

    1979-01-01

    The paper discusses some of the features of high energy lepton-hadron scattering, including the observed (Bjorken) scaling behavior. The cross-sections where all hadron final states are summed over, are examined and the general formulas for the differential cross-section are examined. The subjects of scaling, breaking and phenomenological consequences are studied, and a list of what ultra-high energy neutrino physics can teach QCD is given

  7. Ultra high field magnetic resonance imaging

    International Nuclear Information System (INIS)

    Lethimonnier, F.; Vedrine, P.

    2007-01-01

    Understanding human brain function, brain development and brain dysfunction is one of the great challenges of the twenty first century. Biomedical imaging has now run up against a number of technical constraints that are exposing limits to its potential. In order to overcome the current limits to high-field magnetic resonance cerebral imaging (MRI) and unleash its fullest potential, the Cea has built NeuroSpin, an ultra-high-field neuroimaging facility at its Saclay centre (in the Essonne). NeuroSpin already boasts three fully operational MRI systems. The first is a 3-tesla high-field system and the second is a very-high-field 7-tesla system, both of which are dedicated to clinical studies and investigations in humans, while the third is an ultra-high-field 17.65-tesla system designed for studies on small animals. In 2011, NeuroSpin will be commissioning an 11.7-tesla ultra-high-field system of unprecedented power that is designed for research on human subjects. The level of the magnetic field and the scale required will make this joint French-German project to build the magnet a breakthrough in the international arena. (authors)

  8. Low velocity impact behaviour of ultra high strength concrete panels

    Indian Academy of Sciences (India)

    Ultra high strength concrete; panel; drop weight test; impact analysis;. ABAQUS. 1. Introduction. Ultra high strength concrete ... Knight (2012) investigated the dynamic behaviour of steel fibre reinforced concrete plates under impact loading with ...

  9. Molecular genetic studies on irradiated wheat plants

    International Nuclear Information System (INIS)

    Saleh, O.M.

    2002-01-01

    Composite genotype(octamer hybrid) was obtained from crossing among eight Egyptian hexaploid wheat cultivars differing in their tolerance to drought stress to produce a genotype, which can economize on the irrigation water requirements or can tolerate drought stress. Gamma irradiation with 10-Krad was used to induce mutations, which could improve drought tolerance for this composite. From eight Egyptian wheat cultivars, two were chosen as drought tolerant and drought sensitive genotypes (G-160 and Sk-61, respectively. They were evaluated along with their F1 and F2 for their relative drought tolerance for some yield-related traits. Bulked segregating analysis developed some RAPD and SSR markers with different primers, which were considered as molecular for drought tolerance in wheat. Hal 2-like gene was introduced into Egyptian wheat cultivar G-164 via micro projectile bombardment. Two putative transgenic plants were successfully detected by leaf painting with the herbicide basta. PCR/ Southern blotting analysis indicated the presence of both/either bar and/or Hal 2-like genes in the genomic background of the two transgenic plants

  10. Ultra-high vacuum technology for accelerators

    CERN Multimedia

    CERN. Geneva. Audiovisual Unit; Hilleret, Noël; Strubin, Pierre M

    2002-01-01

    The lectures will start with a review of the basics of vacuum physics required to build Ultra High Vacuum (UHV) systems, such as static and dynamic outgassing. Before reviewing the various pumping and measurement devices, including the most modern one like Non Evaporable Getter (NEG) coatings, an overview of adequate materials to be used in UHV systems will be given together with their treatment (e.g. cleaning procedures and bake out). Practical examples based on existing or future accelerators will be used to illustrate the topics. Finally, a short overview of modern vacuum controls and interlocks will be given.

  11. Hardon cross sections at ultra high energies

    International Nuclear Information System (INIS)

    Yodh, G.B.

    1987-01-01

    A review of results on total hadronic cross sections at ultra high energies obtained from a study of longitudinal development of cosmic ray air showers is given. The experimental observations show that proton-air inelastic cross section increases from 275 mb to over 500 mb as the collision energy in the center of mass increases from 20 GeV to 20 TeV. The proton-air inelastic cross section, obtained from cosmic ray data at √s = 30 TeV, is compared with calculations using various different models for the energy variation of the parameters of the elementary proton-proton interaction. Three conclusions are derived

  12. Ultra-high vacuum photoelectron linear accelerator

    Science.gov (United States)

    Yu, David U.L.; Luo, Yan

    2013-07-16

    An rf linear accelerator for producing an electron beam. The outer wall of the rf cavity of said linear accelerator being perforated to allow gas inside said rf cavity to flow to a pressure chamber surrounding said rf cavity and having means of ultra high vacuum pumping of the cathode of said rf linear accelerator. Said rf linear accelerator is used to accelerate polarized or unpolarized electrons produced by a photocathode, or to accelerate thermally heated electrons produced by a thermionic cathode, or to accelerate rf heated field emission electrons produced by a field emission cathode.

  13. Detecting ultra high energy neutrinos with LOFAR

    International Nuclear Information System (INIS)

    Mevius, M.; Buitink, S.; Falcke, H.; Hörandel, J.; James, C.W.; McFadden, R.; Scholten, O.; Singh, K.; Stappers, B.; Veen, S. ter

    2012-01-01

    The NuMoon project aims to detect signals of Ultra High Energy (UHE) Cosmic Rays with radio telescopes on Earth using the Lunar Cherenkov technique at low frequencies (∼150MHz). The advantage of using low frequencies is the much larger effective detecting volume, with as trade-off the cut-off in sensitivity at lower energies. A first upper limit on the UHE neutrino flux from data of the Westerbork Radio Telescope (WSRT) has been published, while a second experiment, using the new LOFAR telescope, is in preparation. The advantages of LOFAR over WSRT are the larger collecting area, the better pointing accuracy and the use of ring buffers, which allow the implementation of a sophisticated self-trigger algorithm. The expected sensitivity of LOFAR reaches flux limits within the range of some theoretical production models.

  14. Multilayer ultra-high-temperature ceramic coatings

    Science.gov (United States)

    Loehman, Ronald E [Albuquerque, NM; Corral, Erica L [Tucson, AZ

    2012-03-20

    A coated carbon-carbon composite material with multiple ceramic layers to provide oxidation protection from ultra-high-temperatures, where if the carbon-carbon composite material is uninhibited with B.sub.4C particles, then the first layer on the composite material is selected from ZrB.sub.2 and HfB.sub.2, onto which is coated a layer of SiC coated and if the carbon-carbon composite material is inhibited with B.sub.4C particles, then protection can be achieved with a layer of SiC and a layer of either ZrB.sub.2 and HfB.sub.2 in any order.

  15. Ultra-High-Energy Cosmic Rays

    CERN Document Server

    Dova, M.T.

    2015-05-22

    The origin of the ultra high energy cosmic rays (UHECR) with energies above E > 10 17 eV, is still unknown. The discovery of their sources will reveal the engines of the most energetic astrophysical accelerators in the universe. This is a written version of a series of lectures devoted to UHECR at the 2013 CERN-Latin-American School of High-Energy Physics. We present anintroduction to acceleration mechanisms of charged particles to the highest energies in astrophysical objects, their propagation from the sources to Earth, and the experimental techniques for their detection. We also discuss some of the relevant observational results from Telescope Array and Pierre Auger Observatory. These experiments deal with particle interactions at energies orders of magnitude higher than achieved in terrestrial accelerators.

  16. Molecular characteristics of fungus trichoderma viride irradiated gamma rays

    International Nuclear Information System (INIS)

    Dadang Sudrajat; Nana Mulyana; Tri Retno DL; Rika Heriyani; Almaida

    2016-01-01

    Information about the genetic changes due to irradiation on the fungus Trichoderma viride is indispensable in order to improve the ability of these isolates for the delignification of lignocellulose. This study aims to determine the molecular characteristics of isolates fungus Trichoderma viride after irradiation with gamma rays through an approach expression of protein profiles and molecular markers random amplified polymorphic DNA (RAPD). Irradiation doses used in this study are 6 levels i.e 0; 75; 125; 250; 375; 500 and 750 Gy with a dose rate of 0.21 kGy / hour. Protein and DNA extraction isolate is done using the method of extracting phosphate buffer pH 7 and CTAB- phenol-chloroform extraction. Protein in the supernatant was analyzed by electrophoresis (SDS-gel polyacrylamide) to produce a protein fingerprint profile. Randomly amplified polymorphic DNA (RAPD) markers were used to estimate the genetic variations between 7 isolates of irradiated Trichoderma viride which were RAPD reactions using 3 random primers. The results showed that protein profiles generated by irradiation isolates and the control (no irradiation) gave a different pattern, especially at doses of irradiation 250-750 Gy based dendrogram analysis. DNA-RAPD profile showed a high genetic variation between the isolates were irradiated at a dose of 250; 375; 500 and 750 Gy and isolates the control (0 Gy); 75; 125 Gy with 5 cluster formation. Dendrogram analysis showed the coefficient of similarity between 0.62 to 0.68. (author)

  17. Molecular mechanisms of erythrocyte photo-irradiation

    International Nuclear Information System (INIS)

    Ferreira, W.T.; Souza, M.C.

    1985-01-01

    The role of singlet oxygen and the lipid peroxidation of erythrocyte membrane are studied. The irradiation of erythrocytes with visible light in the presence of a photodynamic mediator (toluidine blue) is reported. A system of light application by optical fiber, connected to a catheter is suggested for local instillation of the photosensitizing agent. (M.A.C.) [pt

  18. Molecular weights and molecular weight distributions of irradiated cellulose fibers by gel permeation chromatography

    International Nuclear Information System (INIS)

    Kusama, Y.; Kageyama, E.; Shimada, M.; Nakamura, Y.

    1976-01-01

    Radiation degradation of cellulose fibers was investigated by gel permeation chromatography (GPC). Scoured cotton of Mexican variety (cellulose I), Polynosic rayon (cellulose II), and their microcrystalline celluloses obtained by hydrolysis of the original fibers were irradiated by Co-60 γ-rays under vacuum or humid conditions. The irradiated samples were then nitrated under nondegradative conditions. The molecular weights and molecular weight distributions were measured by GPC using tetrahydrofuran as solvent. The relationship between molecular weight and elution count was obtained with cellulose trinitrate standards fractionated by preparative GPC. The degree of polymerization of the fibers decreased with increasing irradiation dose, but their microcrystalline celluloses were only slightly degraded by irradiation, especially in microcrystalline cellulose from cellulose I. Degradation of the fibers irradiated under humid conditions was less than that irradiated under vacuum. It was found that the G-values for main-chain scission for the irradiated cellulose I, cellulose II, microcrystalline cellulose I, and microcrystalline cellulose II were 2.8, 2.9, less than 1, and 2.9, respectively, but the G-value for main-chain scission for the irradiated cellulose II was increased to 11.2 at irradiation doses above 3 Mrad. Consequently, it is inferred that cellulose molecules in the amorphous regions are degraded more readily, and the well-aligned molecules in crystalline regions are not as easily degraded by irradiation

  19. Ultra high performance concrete dematerialization study

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-03-01

    Concrete is the most widely used building material in the world and its use is expected to grow. It is well recognized that the production of portland cement results in the release of large amounts of carbon dioxide, a greenhouse gas (GHG). The main challenge facing the industry is to produce concrete in an environmentally sustainable manner. Reclaimed industrial by-proudcts such as fly ash, silica fume and slag can reduce the amount of portland cement needed to make concrete, thereby reducing the amount of GHGs released to the atmosphere. The use of these supplementary cementing materials (SCM) can also enhance the long-term strength and durability of concrete. The intention of the EcoSmart{sup TM} Concrete Project is to develop sustainable concrete through innovation in supply, design and construction. In particular, the project focuses on finding a way to minimize the GHG signature of concrete by maximizing the replacement of portland cement in the concrete mix with SCM while improving the cost, performance and constructability. This paper describes the use of Ductal{sup R} Ultra High Performance Concrete (UHPC) for ramps in a condominium. It examined the relationship between the selection of UHPC and the overall environmental performance, cost, constructability maintenance and operational efficiency as it relates to the EcoSmart Program. The advantages and challenges of using UHPC were outlined. In addition to its very high strength, UHPC has been shown to have very good potential for GHG emission reduction due to the reduced material requirements, reduced transport costs and increased SCM content. refs., tabs., figs.

  20. Electron beam irradiation effect on nanostructured molecular sieve catalysts

    International Nuclear Information System (INIS)

    Yuan Zhongyong; Zhou Wuzong; Parvulescu, Viorica; Su Baolian

    2003-01-01

    Electron impact can induce chemical changes on particle surfaces of zeolites and molecular sieve catalysts. Some experimental observations of electron irradiation effect on molecular sieve catalysts are presented, e.g., electron-beam-induced growth of bare silver nanowires from zeolite crystallites, formation of vesicles in calcium phosphate, migration of microdomains in iron-oxide doped mesoporous silicas, structural transformation from mesostructured MCM-41 to microporous ZSM-5, etc. The formation mechanisms of the surface structures are discussed

  1. Moldagem por compressão a frio do polietileno de ultra alto peso molecular. Parte 1: influência do tamanho, distribuição e morfologia da partícula na densidade a verde Cold compression molding of ultra high molecular weight polyethylene. Part 1: influence of the size, distribution and morphology of particles on the green density

    Directory of Open Access Journals (Sweden)

    Bernadete A. Bittencourt

    2009-01-01

    Full Text Available Neste trabalho foram investigadas as características de amostras de pó de polietileno de ultra alto peso molecular (PEUAPM, tais como porosidade, morfologia, tamanho médio e distribuição de partícula, que são importantes na moldagem por compressão a frio. Também foi avaliada a influência dessas características na densidade a verde de pré-formas. As amostras dos pós foram caracterizadas por calorimetria diferencial de varredura (DSC, análise granulométrica, absorção de óleo, área superficial, porosimetria de mercúrio, fluidez do pó, densidade de compactação, densidade aparente e microscopia eletrônica de varredura (MEV. Através das técnicas de caracterização estudadas ficou evidenciado que as características da partícula citadas anteriormente, assim como o parâmetro de densificação (DP, que é função direta da porosidade interparticular, favorecem a densidade a verde relativa (DVR e consequentemente a tensão de resistência à flexão (TRF.In this paper an investigation was made of the characteristics of Ultra High Molecular Weight Polyethylene (UHMWPE powder samples, including porosity, particles average size, size distribution and morphology, which are important in cold compression molding. The influence of these characteristics on the green density of molded pre-shapes was also investigated. The UHMWPE powder samples were characterized by Differential Scanning Calorimetry (DSC, granulometric analysis, oil absorption, surface area, mercury porosity, density compaction, apparent density and Scanning Electron Microscopy (SEM. The characterization techniques used demonstrate that the UHMWPE particles characteristics cited above as well as the densification parameter (DP, which is a direct function of the interparticles porosity, affect the relative green density (RGD and hence, the flexural tensile strength (FTS.

  2. Mid-infrared supercontinuum covering the 1.4–13.3 μm molecular fingerprint region using ultra-high NA chalcogenide step-index fibre

    DEFF Research Database (Denmark)

    Petersen, Christian Rosenberg; Møller, Uffe Visbech; Kubat, Irnis

    2014-01-01

    -power laser diodes, quantum cascade lasers and synchrotron radiation have precluded mid-infrared applications where the spatial coherence, broad bandwidth, high brightness and portability of a supercontinuum laser are all required. Here, we demonstrate experimentally that launching intense ultra-short pulses...... the potential of fibres to emit across the mid-infrared molecular ‘fingerprint region’, which is of key importance for applications such as early cancer diagnostics3, gas sensing and food quality control....

  3. Basic principles of molecular effects of irradiation.

    Science.gov (United States)

    Selzer, Edgar; Hebar, Alexandra

    2012-02-01

    In order to understand the consequences of radiation a thorough understanding of the radiobiological mechanisms of the molecular up to the clinical level is of importance. Radiobiology therefore combines the basic principles of physics as well as biology and medicine and is concerned with the action of radiation from the subcellular level up to the living organism. Topics of interest and relevance are covered in much more broadness as is possible in the short following article in the literature to which the interested reader is referred to. Classical books in this field were written by Steel et al. (1989) as well as by Hall (1994). Topics usually covered by radiobiological reviews are the classification of different types of radiation, cell cycle dependency of radiation effects, types of radiation damage and cell death, dose response curves, measurement of radiation damage, the oxygen effect, relative biological effectiveness, the influence of dose rate, and several other important research areas. This short overview will concentrate on a subset of radiobiological topics of high importance and relative novelty.

  4. Influence of the graphite type in the mechanical properties of graphene nanosheets and ultra high molecular weight polyethylene (GN/UHMWPE) nanocomposites; Influencia do tipo de grafite nas propriedades mecanicas do nanocomposito de nanolaminas de grafeno com polietileno de ultra alta massa molar (NG/PEUAPM)

    Energy Technology Data Exchange (ETDEWEB)

    Lima, M.E. de A.; Coutinho, S.V.; Fim, F. de C., E-mail: fabianafim@ct.ufpb.br [Universidade Federal da Paraiba (UFPB), Joao Pessoa, PB (Brazil). Departamento de Engenharia de Materiais

    2016-07-01

    This paper studies the mechanical properties of graphene nanosheets and ultra high molecular weight polyethylene (GN/UHMWPE) nanocomposites. The graphene nanosheets were obtained by two methods: the first, from Graphite Micrograf HC11 after 8 hours in a ultrasound bath in 70% alcoholic solution; the second, from Graflake 9950 prepared by oxidizing with H{sub 2}SO{sub 4}/HNO{sub 3} (4:1), followed by thermal expansion at 1050°C for 30 seconds and ultrasound bath for 20 hours. Both were oven dried for 24 hours at 110°C and subsequently added to the polymer in percentages of 0.5, 1.0 and 1.5% (w/w). The powders of the nanocomposites were mixed in a ball mill for 1 hour and molded by hot compression. XRD and SEM images was possible to verify that the Graflake's GN had higher delamination that the Micrograph's GN. The mechanical properties were affected in different percentages for each graphite type. (author)

  5. Effects of the ultra-high pressure on structure and α-glucosidase inhibition of polysaccharide from Astragalus.

    Science.gov (United States)

    Zhu, Zhen-Yuan; Luo, You; Dong, Guo-Ling; Ren, Yuan-Yuan; Chen, Li-Jing; Guo, Ming-Zhu; Wang, Xiao-Ting; Yang, Xue-Ying; Zhang, Yongmin

    2016-06-01

    A novel homogeneous polysaccharide fraction (APS) was extracted from Astragalus by hot water and purified by Sephadex G-100 and G-75 column. Its molecular weight was 693kDa. APS and APS with ultra-high pressure treatment exhibited significant inhibitory abilities on a-glucosidase, inhibition rate from high to low in order was 400MPa-APS, 300MPa-APS, 500MPa-APS and APS. The inhibition ​percentage of 400MPa-APS (1.5mg/mL) was 49% (max.). This suggested that the inhibitory activity of APS on a-glucosidase was improved by ultra-high pressure treatment. FT-IR, SEM, CD spectra, atomic force microscope and Congo red test analysis of APS and 400MPa-APS showed ultra-high pressure treatment didn't change the preliminary structure but had an effect on its advanced structure. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Ultra-high-speed Optical Signal Processing using Silicon Photonics

    DEFF Research Database (Denmark)

    Oxenløwe, Leif Katsuo; Ji, Hua; Jensen, Asger Sellerup

    with a photonic layer on top to interconnect them. For such systems, silicon is an attractive candidate enabling both electronic and photonic control. For some network scenarios, it may be beneficial to use optical on-chip packet switching, and for high data-density environments one may take advantage...... of the ultra-fast nonlinear response of silicon photonic waveguides. These chips offer ultra-broadband wavelength operation, ultra-high timing resolution and ultra-fast response, and when used appropriately offer energy-efficient switching. In this presentation we review some all-optical functionalities based...... on silicon photonics. In particular we use nano-engineered silicon waveguides (nanowires) [1] enabling efficient phasematched four-wave mixing (FWM), cross-phase modulation (XPM) or self-phase modulation (SPM) for ultra-high-speed optical signal processing of ultra-high bit rate serial data signals. We show...

  7. Stretchers and compressors for ultra-high power laser systems

    Energy Technology Data Exchange (ETDEWEB)

    Yakovlev, I V [Institute of Applied Physics, Russian Academy of Sciences, Nizhnii Novgorod (Russian Federation)

    2014-05-30

    This review is concerned with pulse stretchers and compressors as key components of ultra-high power laser facilities that take advantage of chirped-pulse amplification. The potentialities, characteristics, configurations and methods for the matching and alignment of these devices are examined, with particular attention to the history of the optics of ultra-short, ultra-intense pulses before and after 1985, when the chirped-pulse amplification method was proposed, which drastically changed the view of the feasibility of creating ultra-high power laser sources. The review is intended primarily for young scientists and experts who begin to address the amplification and compression of chirped pulses, experts in laser optics and all who are interested in scientific achievements in the field of ultra-high power laser systems. (review)

  8. Shock characterization of an ultra-high strength concrete

    International Nuclear Information System (INIS)

    Erzar, B.; Pontiroli, C.; Buzaud, E.

    2016-01-01

    Nowadays, the design of protective structures may imply ultra-high performance concretes. These materials present a compressive strength 5 times higher than standard concretes. However, few reliable data on the shock response of such materials are available in the literature. Thus, a characterization of an ultra-high strength concrete has been conducted by means of hydrostatic and triaxial tests in the quasi-static regime, and plate impact experiments for shock response. Data have been gathered up to 6 GPa and a simple modelling approach has been applied to get a reliable representation of the shock compression of this concrete. (authors)

  9. Status of Ultra-High Energy Cosmic Rays

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    I will review the recent results on Ultra-High energy cosmic rays obtained by the Auger and Telescope Array Observatories, and discuss some of the Astrophysical scenarios that could account for them, a connection with LHC results  as well as the possible connections to neutrino and gamma ray observations.

  10. Soliton-based ultra-high speed optical communications

    Indian Academy of Sciences (India)

    All these facts are the outcome of research on optical solitons in fibers in spite of the fact that the commonly used RZ format is not always called a soliton format. The overview presented here attempts to incorporate the role of soliton-based communications research in present day ultra-high speed communications.

  11. Influence of curing regimes on compressive strength of ultra high

    Indian Academy of Sciences (India)

    The present paper is aimed to identify an efficient curing regime for ultra high performance concrete (UHPC), to achieve a target compressive strength more than 150 MPa, using indigenous materials. The thermal regime plays a vital role due to the limited fineness of ingredients and low water/binder ratio. By activation of the ...

  12. Ultra high performance liquid chromatography of seized drugs

    NARCIS (Netherlands)

    Lurie, I.S.

    2010-01-01

    The primary goal of this thesis is to investigate the use of ultra high performance liquid chromatography (UHPLC) for the analysis of seized drugs. This goal was largely achieved and significant progress was made in achieving improved separation and detection of drugs of forensic interest.

  13. Ultra high energy cosmic rays and magnetic fields

    Energy Technology Data Exchange (ETDEWEB)

    Stanev, Todor; Engel, Ralph; Alvarez-Muniz, Jaime; Seckel, David

    2002-07-01

    We follow the propagation of ultra high energy protons in the presence of random and regular magnetic fields and discuss some of the changes in the angular and energy distributions of these particles introduced by the scattering in the magnetic fields.

  14. Ultra high energy cosmic rays and magnetic fields

    International Nuclear Information System (INIS)

    Stanev, Todor; Engel, Ralph; Alvarez-Muniz, Jaime; Seckel, David

    2002-01-01

    We follow the propagation of ultra high energy protons in the presence of random and regular magnetic fields and discuss some of the changes in the angular and energy distributions of these particles introduced by the scattering in the magnetic fields

  15. Fiber based hydrophones for ultra-high energy neutrino detection

    NARCIS (Netherlands)

    Buis, E.J.; Doppenberg, E.J.J.; Eijk, D. van; Lahmann, R.; Nieuwland, R.A.; Toet, P.M.

    2014-01-01

    It is a well studied process [1, 2] that energy deposition of cosmic ray particles in water that generate thermo-acoustic signals. Hydrophones of sufficient sensitivity could measure this signal and provide a means of detecting ultra-high energetic cosmic neutrinos. We investigate optical

  16. Super Boiler: First Generation, Ultra-High Efficiency Firetube Boiler

    Energy Technology Data Exchange (ETDEWEB)

    None

    2006-06-01

    This factsheet describes a research project whose goal is to develop and demonstrate a first-generation ultra-high-efficiency, ultra-low emissions, compact gas-fired package boiler (Super Boiler), and formulate a long-range RD&D plan for advanced boiler technology out to the year 2020.

  17. Molecular genetic studies on some irradiated medicinal plants

    Energy Technology Data Exchange (ETDEWEB)

    Alam el-din, H.F.M

    2007-07-01

    This thesis aimed to study the molecular characterization , the phylogenetic relationships among the four mentha and the three ocimum species and to get some species-specific markers. twenty-one RAPD and 10 ISSR primers were used which showed high polymorphism among the species and detected 150 molecular markers for these genotypes (100 using RAPD and 50 by ISSR-analyses). detection of the phylogenetic relationships based on the three studied systems (RAPD,ISSR and their combined analyses ) indicated that these techniques succeeded in separating the seven species into two main clusters of the two mentha and ocimum genera. SDS-protein patterns characterized the seven genotypes based on presence/ absence and staining intensities of 14 polypeptide bands into two main groups.the effect of four doses of gamma irradiation on eight active components of volatile oils and SDS-protein pattern of stems of mentha viridis indicated that low levels of gamma irradiation could improve the value of some active components of medicinal plants such as menthol in mentha viridis.

  18. Aromatic polymers of increased resistance to flow and molecular weight obtained by irradiation

    International Nuclear Information System (INIS)

    Staniland, P.A.; Jarrett, G.

    1976-01-01

    Aromatic polymers of increased resistance to flow and increased molecular weight are obtained by irradiation using β rays or gamma rays at temperatures up to 400 0 C of an aromatic polymer whose molecular chains comprise benzenoid groups and bivalent linking groups, and where irradiation is gamma rays by heating subsequent to irradiation at 200 0 C to 400 0 C. The polymeric materials having increased molecular weight are useful for coating non-cooking surfaces of cookware

  19. Chemical fingerprint of Ganmaoling granule by double-wavelength ultra high performance liquid chromatography and ultra high performance liquid chromatography with quadrupole time-of-flight mass spectrometry.

    Science.gov (United States)

    Lou, Qiong; Ye, Xiaolan; Zhou, Yingyi; Li, Hua; Song, Fenyun

    2015-06-01

    A method incorporating double-wavelength ultra high performance liquid chromatography with quadrupole time-of-flight mass spectrometry was developed for the investigation of the chemical fingerprint of Ganmaoling granule. The chromatographic separations were performed on an ACQUITY UPLC HSS C18 column (2.1 × 50 mm, 1.8 μm) at 30°C using gradient elution with water/formic acid (1%) and acetonitrile at a flow rate of 0.4 mL/min. A total of 11 chemical constituents of Ganmaoling granule were identified from their molecular weight, UV spectra, tandem mass spectrometry data, and retention behavior by comparing the results with those of the reference standards or literature. And 25 peaks were selected as the common peaks for fingerprint analysis to evaluate the similarities among 25 batches of Ganmaoling granule. The results of principal component analysis and orthogonal projection to latent structures discriminant analysis showed that the important chemical markers that could distinguish the different batches were revealed as 4,5-di-O-caffeoylquinic acid, 3,5-di-O-caffeoylquinic acid, and 4-O-caffeoylquinic acid. This is the first report of the ultra high performance liquid chromatography chemical fingerprint and component identification of Ganmaoling granule, which could lay a foundation for further studies of Ganmaoling granule. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Photoinduced optical anisotropy in azobenzene methacrylate block copolymers: Influence of molecular weight and irradiation conditions

    DEFF Research Database (Denmark)

    Gimeno, Sofia; Forcen, Patricia; Oriol, Luis

    2009-01-01

    The photoinduced anisotropy in a series of azomethacrylate block copolymers with different Molecular weights and azo contents has been investigated under several irradiation conditions. Depending on molecular weight and composition, different microstructures (disordered, lamellar, spherical) appe...

  1. Investigation and basic evaluation for ultra-high burnup fuel cladding material

    International Nuclear Information System (INIS)

    Ioka, Ikuo; Nagase, Fumihisa; Futakawa, Masatoshi; Kiuchi, Kiyoshi

    2001-03-01

    In ultra-high burnup of the power reactor, it is an essential problem to develop the cladding with excellent durability. First, development history and approach of the safety assessment of Zircaloy for the high burnup fuel were summarized in the report. Second, the basic evaluation and investigation were carried out on the material with high practicability in order to select the candidate materials for the ultra-high burnup fuel. In addition, the basic research on modification technology of the cladding surface was carried out from the viewpoint of the addition of safety margin as a cladding. From the development history of the zirconium alloy including the Zircaloy, it is hard to estimate the results of in-pile test from those of the conventional corrosion test (out-pile test). Therefore, the development of the new testing technology that can simulate the actual environment and the elucidation of the corrosion-controlling factor of the cladding are desired. In cases of RIA (Reactivity Initiated Accident) and LOCA (Loss of Coolant Accident), it seems that the loss of ductility in zirconium alloys under heavy irradiation and boiling of high temperature water restricts the extension of fuel burnup. From preliminary evaluation on the high corrosion-resistance materials (austenitic stainless steel, iron or nickel base superalloys, titanium alloy, niobium alloy, vanadium alloy and ferritic stainless steel), stabilized austenitic stainless steels with a capability of future improvement and high-purity niobium alloys with a expectation of the good corrosion resistance were selected as candidate materials of ultra-high burnup cladding. (author)

  2. Functional aluminum alloys for ultra high vacuum use

    International Nuclear Information System (INIS)

    Kato, Yutaka; Tsukamoto, Kenji; Isoyama, Eizo

    1985-01-01

    Ultra high vacuum systems made of aluminum alloys are actively developed. The reasons for using aluminum alloys are low residual radioactivity, light weight, good machinability, good thermal conductivity, non-magnetism. The important function required for ultra high vacuum materials is low outgassing rate, but surface gas on ordinary aluminum is much. Then the research on aluminum surface structure with low outgassing rate has been made and the special extrusion method, that is, extrusion method with the conditions of preventing air from entering inside of pipe and of taking in mixture gas of Ar + O 2 , was developed. 6063 alloy obtained by special extrusion method showed low outgassing rate (2 x 10 -13 Torr. 1/s. cm 2 ) by only 150 deg C, 24 h baking. For the future it will be important to develop aluminum alloys with low dynamic outgassing rate as well as low static outgassing rate. (author)

  3. Ultra high frequency induction welding of powder metal compacts

    Energy Technology Data Exchange (ETDEWEB)

    Cavdar, U.; Gulsahin, I.

    2014-10-01

    The application of the iron based Powder Metal (PM) compacts in Ultra High Frequency Induction Welding (UHFIW) were reviewed. These PM compacts are used to produce cogs. This study investigates the methods of joining PM materials enforceability with UHFIW in the industry application. Maximum stress and maximum strain of welded PM compacts were determined by three point bending and strength tests. Microhardness and microstructure of induction welded compacts were determined. (Author)

  4. Ultra high frequency induction welding of powder metal compacts

    International Nuclear Information System (INIS)

    Cavdar, U.; Gulsahin, I.

    2014-01-01

    The application of the iron based Powder Metal (PM) compacts in Ultra High Frequency Induction Welding (UHFIW) were reviewed. These PM compacts are used to produce cogs. This study investigates the methods of joining PM materials enforceability with UHFIW in the industry application. Maximum stress and maximum strain of welded PM compacts were determined by three point bending and strength tests. Microhardness and microstructure of induction welded compacts were determined. (Author)

  5. Ultra-high-field magnets for future hadron colliders

    International Nuclear Information System (INIS)

    McIntyre, P.M.; Shen, W.

    1997-01-01

    Several new concepts in magnetic design and coil fabrication are being incorporated into designs for ultra-high field collider magnets: a 16 Tesla block-coil dual dipole, also using Nb 3 Sn cable, featuring simple pancake coil construction and face-loaded prestress geometry; a 330 T/m block-coil quadrupole; and a ∼ 20 Tesla pipe-geometry dual dipole, using A15 or BSCCO tape. Field design and fabrication issues are discussed for each magnet

  6. Ultra-high energy cosmic rays: Setting the stage

    Science.gov (United States)

    Sokolsky, P.

    2013-06-01

    The history of ultra-high energy cosmic ray physics is reviewed from the post-war era of arrays such as Volcano Ranch, Haverah Park and Akeno to the development of air-fluorescence and current hybrid arrays. The aim of this paper is to present the background information needed for a better understanding of the current issues in this field that are discussed in much greater depth in the rest of this conference.

  7. Ultra-high energy cosmic rays: Setting the stage

    Directory of Open Access Journals (Sweden)

    Sokolsky P.

    2013-06-01

    Full Text Available The history of ultra-high energy cosmic ray physics is reviewed from the post-war era of arrays such as Volcano Ranch, Haverah Park and Akeno to the development of air-fluorescence and current hybrid arrays. The aim of this paper is to present the background information needed for a better understanding of the current issues in this field that are discussed in much greater depth in the rest of this conference.

  8. A swimming pool array for ultra high energy showers

    Science.gov (United States)

    Yodh, Gaurang B.; Shoup, Anthony; Barwick, Steve; Goodman, Jordan A.

    1992-11-01

    A very preliminary design concept for an array using water Cherenkov counters, built out of commercially available backyard swimming pools, to sample the electromagnetic and muonic components of ultra high energy showers at large lateral distances is presented. The expected performance of the pools is estimated using the observed lateral distributions by scintillator and water Cherenkov arrays at energies above 1019 eV and simulations.

  9. Ultra-high Performance Liquid Chromatography in Steroid Analysis

    OpenAIRE

    Salonen, Fanny

    2017-01-01

    The latest version of liquid chromatography is ultra-high performance (or pressure) chromatography (UHPLC). In the technique, short and narrow-bore columns with particle sizes below 3 µm are used. The extremely high pressure used results in very short analysis times, excellent separation, and good resolution. This makes UHPLC a good choice for steroidal analysis. Steroids are a highly interesting area of study; they can be recognized as biomarkers for several diseases and are a relevant topic...

  10. Radiobiological influence of megavoltage electron pulses of ultra-high pulse dose rate on normal tissue cells.

    Science.gov (United States)

    Laschinsky, Lydia; Karsch, Leonhard; Leßmann, Elisabeth; Oppelt, Melanie; Pawelke, Jörg; Richter, Christian; Schürer, Michael; Beyreuther, Elke

    2016-08-01

    Regarding the long-term goal to develop and establish laser-based particle accelerators for a future radiotherapeutic treatment of cancer, the radiobiological consequences of the characteristic short intense particle pulses with ultra-high peak dose rate, but low repetition rate of laser-driven beams have to be investigated. This work presents in vitro experiments performed at the radiation source ELBE (Electron Linac for beams with high Brilliance and low Emittance). This accelerator delivered 20-MeV electron pulses with ultra-high pulse dose rate of 10(10) Gy/min either at the low pulse frequency analogue to previous cell experiments with laser-driven electrons or at high frequency for minimizing the prolonged dose delivery and to perform comparison irradiation with a quasi-continuous electron beam analogue to a clinically used linear accelerator. The influence of the different electron beam pulse structures on the radiobiological response of the normal tissue cell line 184A1 and two primary fibroblasts was investigated regarding clonogenic survival and the number of DNA double-strand breaks that remain 24 h after irradiation. Thereby, no considerable differences in radiation response were revealed both for biological endpoints and for all probed cell cultures. These results provide evidence that the radiobiological effectiveness of the pulsed electron beams is not affected by the ultra-high pulse dose rates alone.

  11. Radiobiological influence of megavoltage electron pulses of ultra-high pulse dose rate on normal tissue cells

    International Nuclear Information System (INIS)

    Laschinsky, Lydia; Karsch, Leonhard; Schuerer, Michael; Lessmann, Elisabeth; Beyreuther, Elke; Oppelt, Melanie; Pawelke, Joerg; Richter, Christian

    2016-01-01

    Regarding the long-term goal to develop and establish laser-based particle accelerators for a future radiotherapeutic treatment of cancer, the radiobiological consequences of the characteristic short intense particle pulses with ultra-high peak dose rate, but low repetition rate of laser-driven beams have to be investigated. This work presents in vitro experiments performed at the radiation source ELBE (Electron Linac for beams with high Brilliance and low Emittance). This accelerator delivered 20-MeV electron pulses with ultra-high pulse dose rate of 10"1"0 Gy/min either at the low pulse frequency analogue to previous cell experiments with laser-driven electrons or at high frequency for minimizing the prolonged dose delivery and to perform comparison irradiation with a quasi-continuous electron beam analogue to a clinically used linear accelerator. The influence of the different electron beam pulse structures on the radiobiological response of the normal tissue cell line 184A1 and two primary fibroblasts was investigated regarding clonogenic survival and the number of DNA double-strand breaks that remain 24 h after irradiation. Thereby, no considerable differences in radiation response were revealed both for biological endpoints and for all probed cell cultures. These results provide evidence that the radiobiological effectiveness of the pulsed electron beams is not affected by the ultra-high pulse dose rates alone. (orig.)

  12. Molecular dynamics for irradiation driven chemistry: application to the FEBID process*

    Science.gov (United States)

    Sushko, Gennady B.; Solov'yov, Ilia A.; Solov'yov, Andrey V.

    2016-10-01

    A new molecular dynamics (MD) approach for computer simulations of irradiation driven chemical transformations of complex molecular systems is suggested. The approach is based on the fact that irradiation induced quantum transformations can often be treated as random, fast and local processes involving small molecules or molecular fragments. We advocate that the quantum transformations, such as molecular bond breaks, creation and annihilation of dangling bonds, electronic charge redistributions, changes in molecular topologies, etc., could be incorporated locally into the molecular force fields that describe the classical MD of complex molecular systems under irradiation. The proposed irradiation driven molecular dynamics (IDMD) methodology is designed for the molecular level description of the irradiation driven chemistry. The IDMD approach is implemented into the MBN Explorer software package capable to operate with a large library of classical potentials, many-body force fields and their combinations. IDMD opens a broad range of possibilities for modelling of irradiation driven modifications and chemistry of complex molecular systems ranging from radiotherapy cancer treatments to the modern technologies such as focused electron beam deposition (FEBID). As an example, the new methodology is applied for studying the irradiation driven chemistry caused by FEBID of tungsten hexacarbonyl W(CO)6 precursor molecules on a hydroxylated SiO2 surface. It is demonstrated that knowing the interaction parameters for the fragments of the molecular system arising in the course of irradiation one can reproduce reasonably well experimental observations and make predictions about the morphology and molecular composition of nanostructures that emerge on the surface during the FEBID process.

  13. Ultra-High-Contrast Laser Acceleration of Relativistic Electrons in Solid Targets

    Energy Technology Data Exchange (ETDEWEB)

    Higginson, Drew Pitney [Univ. of California, San Diego, CA (United States)

    2013-01-01

    The cone-guided fast ignition approach to Inertial Con nement Fusion requires laser-accelerated relativistic electrons to deposit kilojoules of energy within an imploded fuel core to initiate fusion burn. One obstacle to coupling electron energy into the core is the ablation of material, known as preplasma, by laser energy proceeding nanoseconds prior to the main pulse. This causes the laser-absorption surface to be pushed back hundreds of microns from the initial target surface; thus increasing the distance that electrons must travel to reach the imploded core. Previous experiments have shown an order of magnitude decrease in coupling into surrogate targets when intentionally increasing the amount of preplasma. Additionally, for electrons to deposit energy within the core, they should have kinetic energies on the order of a few MeV, as less energetic electrons will be stopped prior to the core and more energetic electrons will pass through the core without depositing much energy. Thus a quantitative understanding of the electron energy spectrum and how it responds to varied laser parameters is paramount for fast ignition. For the rst time, this dissertation quantitatively investigates the acceleration of electrons using an ultra-high-contrast laser. Ultra-high-contrast lasers reduce the laser energy that reaches the target prior to the main pulse; drastically reducing the amount of preplasma. Experiments were performed in a cone-wire geometry relevant to fast ignition. These experiments irradiated the inner-tip of a Au cone with the laser and observed electrons that passed through a Cu wire attached to the outer-tip of the cone. The total emission of K x-rays is used as a diagnostic to infer the electron energy coupled into the wire. Imaging the x-ray emission allowed an e ective path-length of electrons within the wire to be determined, which constrained the electron energy spectrum. Experiments were carried out on the ultra-high-contrast Trident laser at Los

  14. ATLAS and ultra high energy cosmic ray physics

    Directory of Open Access Journals (Sweden)

    Pinfold James

    2017-01-01

    Full Text Available After a brief introduction to extended air shower cosmic ray physics the current and future deployment of forward detectors at ATLAS is discussed along with the various aspects of the current and future ATLAS programs to explore hadronic physics. The emphasis is placed on those results and future plans that have particular relevance for high-energy, and ultra high-energy, cosmic ray physics. The possible use of ATLAS as an “underground” cosmic muon observatory is briefly considered.

  15. Functional magnetic resonance imaging with ultra-high fields

    International Nuclear Information System (INIS)

    Windischberger, C.; Schoepf, V.; Sladky, R.; Moser, E.; Fischmeister, F.P.S.

    2010-01-01

    Functional magnetic resonance imaging (fMRI) is currently the primary method for non-invasive functional localization in the brain. With the emergence of MR systems with field strengths of 4 Tesla and above, neuronal activation may be studied with unprecedented accuracy. In this article we present different approaches to use the improved sensitivity and specificity for expanding current fMRT resolution limits in space and time based on several 7 Tesla studies. In addition to the challenges that arise with ultra-high magnetic fields possible solutions will be discussed. (orig.) [de

  16. Photonic Technologies for Ultra-High-Speed Information Highways

    DEFF Research Database (Denmark)

    Bouchoule, S; Lèfevre, R.; Legros, E.

    1999-01-01

    The ACTS project HIGHWAY (AC067) addresses promising ultra-high speed optoelectronic components and system technologies for 40 Gbit/s time-division-multiplexed (TDM) transport systems. Advanced 40 Gbit/s TDM system lab demonstrators are to be realized and tested over installed field fiber testbeds....... This paper reviews the current status of 40 Gbit/s TDM components and subsystem technologies achieved in HIGHWAY. The results of HIGHWAY 40 Gbit/s TDM systems and field tests will be reported in a subsequent paper. (C) 1999 Academic Press....

  17. Design of Ultra High Performance Fiber Reinforced Concrete Shells

    DEFF Research Database (Denmark)

    Jepsen, Michael S.; Lambertsen, Søren Heide; Damkilde, Lars

    2013-01-01

    Fiber Reinforced Concrete shell. The major challenge in the design phase has been securing sufficient stiffness of the structure while keeping the weight at a minimum. The weight/stiffness issue has been investigated by means of the finite element method, to optimize the structure regarding overall......The paper treats the redesign of the float structure of the Wavestar wave energy converter. Previously it was designed as a glass fiber structure, but due to cost reduction requirements a redesign has been initiated. The new float structure will be designed as a double curved Ultra High Performance...

  18. Mechanical properties of irradiated nanowires – A molecular dynamics study

    Energy Technology Data Exchange (ETDEWEB)

    Figueroa, Emilio [Grupo de NanoMateriales, Departamento de Física, Facultad de Ciencias, Universidad de Chile, Casilla, 653 Santiago (Chile); Departamento de Física, Facultad de Ciencias Naturales, Matemática y del Medio Ambiente, Universidad Tecnológica Metropolitana, Santiago 7800002 (Chile); Tramontina, Diego [Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Cuyo, 5500 Mendoza (Argentina); Instituto de Bioingeniería, Universidad de Mendoza, 5500 Mendoza (Argentina); Gutiérrez, Gonzalo, E-mail: gonzalo@fisica.ciencias.uchile.cl [Grupo de NanoMateriales, Departamento de Física, Facultad de Ciencias, Universidad de Chile, Casilla, 653 Santiago (Chile); Bringa, Eduardo [Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Cuyo, 5500 Mendoza (Argentina)

    2015-12-15

    In this work we study, by means of molecular dynamics simulation, the change in the mechanical properties of a gold nanowire with pre-existing radiation damage. The gold nanowire is used as a simple model for a nanofoam, made of connected nanowires. Radiation damage by keV ions leads to the formation of a stacking fault tetrahedron (SFT), and this defect leads to a reduced plastic threshold, as expected, when the nanowire is subjected to tension. We quantify dislocation and twin density during the deformation, and find that the early activation of the SFT as a dislocation source leads to reduced dislocation densities compared to the case without radiation damage. In addition, we observed a total destruction of the SFT, as opposed to a recent simulation study where it was postulated that SFTs might act as self-generating dislocation sources. The flow stress at large deformation is also found to be slightly larger for the irradiated case, in agreement with recent experiments. - Highlights: • Stacking Fault Tetrahedra (SFT) formation proceeds by cascades, containing typically a vacancy cluster and interstitials. • Applied tension leads to the destruction of the SFT, in contrast to a recently reported case of a SFT which soften the NW. • After the initial dislocation activity, strength is controlled by a few surviving dislocations.

  19. Radiobiological response to ultra-short pulsed megavoltage electron beams of ultra-high pulse dose rate.

    Science.gov (United States)

    Beyreuther, Elke; Karsch, Leonhard; Laschinsky, Lydia; Leßmann, Elisabeth; Naumburger, Doreen; Oppelt, Melanie; Richter, Christian; Schürer, Michael; Woithe, Julia; Pawelke, Jörg

    2015-08-01

    In line with the long-term aim of establishing the laser-based particle acceleration for future medical application, the radiobiological consequences of the typical ultra-short pulses and ultra-high pulse dose rate can be investigated with electron delivery. The radiation source ELBE (Electron Linac for beams with high Brilliance and low Emittance) was used to mimic the quasi-continuous electron beam of a clinical linear accelerator (LINAC) for comparison with electron pulses at the ultra-high pulse dose rate of 10(10) Gy min(-1) either at the low frequency of a laser accelerator or at 13 MHz avoiding effects of prolonged dose delivery. The impact of pulse structure was analyzed by clonogenic survival assay and by the number of residual DNA double-strand breaks remaining 24 h after irradiation of two human squamous cell carcinoma lines of differing radiosensitivity. The radiation response of both cell lines was found to be independent from electron pulse structure for the two endpoints under investigation. The results reveal, that ultra-high pulse dose rates of 10(10) Gy min(-1) and the low repetition rate of laser accelerated electrons have no statistically significant influence (within the 95% confidence intervals) on the radiobiological effectiveness of megavoltage electrons.

  20. Microstructure of ultra high performance concrete containing lithium slag.

    Science.gov (United States)

    He, Zhi-Hai; Du, Shi-Gui; Chen, Deng

    2018-04-03

    Lithium slag (LS) is discharged as a byproduct in the process of the lithium carbonate, and it is very urgent to explore an efficient way to recycle LS in order to protect the environments and save resources. Many available supplementary cementitious materials for partial replacement of cement and/or silica fume (SF) can be used to prepare ultra high performance concrete (UHPC). The effect of LS to replace SF partially by weight used as a supplementary cementitious material (0%, 5%, 10% and 15% of binder) on the compressive strengths and microstructure evolution of UHPC has experimentally been studied by multi-techniques including mercury intrusion porosimetry, scanning electron microscope and nanoindentation technique. The results show that the use of LS degrades the microstructure of UHPC at early ages, and however, the use of LS with the appropriate content improves microstructure of UHPC at later ages. The hydration products of UHPC are mainly dominated by ultra-high density calcium-silicate-hydrate (UHD C-S-H) and interfacial transition zone (ITZ) in UHPC has similar compact microstructure with the matrix. The use of LS improves the hydration degree of UHPC and increases the elastic modulus of ITZ in UHPC. LS is a promising substitute for SF for preparation UHPC. Copyright © 2018 Elsevier B.V. All rights reserved.

  1. Systematic Calibration for Ultra-High Accuracy Inertial Measurement Units

    Directory of Open Access Journals (Sweden)

    Qingzhong Cai

    2016-06-01

    Full Text Available An inertial navigation system (INS has been widely used in challenging GPS environments. With the rapid development of modern physics, an atomic gyroscope will come into use in the near future with a predicted accuracy of 5 × 10−6°/h or better. However, existing calibration methods and devices can not satisfy the accuracy requirements of future ultra-high accuracy inertial sensors. In this paper, an improved calibration model is established by introducing gyro g-sensitivity errors, accelerometer cross-coupling errors and lever arm errors. A systematic calibration method is proposed based on a 51-state Kalman filter and smoother. Simulation results show that the proposed calibration method can realize the estimation of all the parameters using a common dual-axis turntable. Laboratory and sailing tests prove that the position accuracy in a five-day inertial navigation can be improved about 8% by the proposed calibration method. The accuracy can be improved at least 20% when the position accuracy of the atomic gyro INS can reach a level of 0.1 nautical miles/5 d. Compared with the existing calibration methods, the proposed method, with more error sources and high order small error parameters calibrated for ultra-high accuracy inertial measurement units (IMUs using common turntables, has a great application potential in future atomic gyro INSs.

  2. Live Ultra-High Definition from the International Space Station

    Science.gov (United States)

    Grubbs, Rodney; George, Sandy

    2017-01-01

    The first ever live downlink of Ultra-High Definition (UHD) video from the International Space Station (ISS) was the highlight of a 'Super Session' at the National Association of Broadcasters (NAB) in April 2017. The Ultra-High Definition video downlink from the ISS all the way to the Las Vegas Convention Center required considerable planning, pushed the limits of conventional video distribution from a space-craft, and was the first use of High Efficiency Video Coding (HEVC) from a space-craft. The live event at NAB will serve as a pathfinder for more routine downlinks of UHD as well as use of HEVC for conventional HD downlinks to save bandwidth. HEVC may also enable live Virtual Reality video downlinks from the ISS. This paper will describe the overall work flow and routing of the UHD video, how audio was synchronized even though the video and audio were received many seconds apart from each other, and how the demonstration paves the way for not only more efficient video distribution from the ISS, but also serves as a pathfinder for more complex video distribution from deep space. The paper will also describe how a 'live' event was staged when the UHD coming from the ISS had a latency of 10+ seconds. Finally, the paper will discuss how NASA is leveraging commercial technologies for use on-orbit vs. creating technology as was required during the Apollo Moon Program and early space age.

  3. Ultra-high pressure water jet: Baseline report

    International Nuclear Information System (INIS)

    1997-01-01

    The ultra-high pressure waterjet technology was being evaluated at Florida International University (FIU) as a baseline technology. In conjunction with FIU's evaluation of efficiency and cost, this report covers the evaluation conducted for safety and health issues. It is a commercially available technology and has been used for various projects at locations throughout the country. The ultra-high pressure waterjet technology acts as a cutting tool for the removal of surface substrates. The Husky trademark pump feeds water to a lance that directs the high pressure water at the surface to be removed. The safety and health evaluation during the testing demonstration focused on two main areas of exposure. These were dust and noise. The dust exposure was found to be minimal, which would be expected due to the wet environment inherent in the technology, but noise exposure was at a significant level. Further testing for noise is recommended because of the outdoor environment where the testing demonstration took place. In addition, other areas of concern found were arm-hand vibration, ergonomics, heat stress, tripping hazards, electrical hazards, lockout/tagout, fall hazards, slipping hazards, hazards associated with the high pressure water, and hazards associated with air pressure systems

  4. Development and optimization of ultra-high performance supercritical fluid chromatography mass spectrometry method for high-throughput determination of tocopherols and tocotrienols in human serum

    Czech Academy of Sciences Publication Activity Database

    Pilařová, V.; Gottvald, T.; Svoboda, P.; Novák, Ondřej; Benešová, K.; Běláková, S.; Nováková, L.

    2016-01-01

    Roč. 934, AUG 31 (2016), s. 252-265 ISSN 0003-2670 R&D Projects: GA MŠk(CZ) LO1204 Institutional support: RVO:61389030 Keywords : Ultra-high performance supercritical fluid chromatography * Mass spectrometry * Liquid liquid extraction Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.950, year: 2016

  5. Magnetic resonance imaging and spectroscopy at ultra high fields

    International Nuclear Information System (INIS)

    Neuberger, Thomas

    2009-01-01

    The goal of the work presented in this thesis was to explore the possibilities and limitations of MRI / MRS using an ultra high field of 17.6 tesla. A broad range of specific applications and MR methods, from MRI to MRSI and MRS were investigated. The main foci were on sodium magnetic resonance spectroscopic imaging of rodents, magnetic resonance spectroscopy of the mouse brain, and the detection of small amounts of iron labeled stem cells in the rat brain using MRI Sodium spectroscopic imaging was explored since it benefits tremendously from the high magnetic field. Due to the intrinsically low signal in vivo, originating from the low concentrations and short transverse relaxation times, only limited results have been achieved by other researchers until now. Results in the literature include studies conducted on large animals such as dogs to animals as small as rats. No studies performed on mice have been reported, despite the fact that the mouse is the most important laboratory animal due to the ready availability of transgenic strains. Hence, this study concentrated on sodium MRSI of small rodents, mostly mice (brain, heart, and kidney), and in the case of the brain on young rats. The second part of this work concentrated on proton magnetic resonance spectroscopy of the rodent brain. Due to the high magnetic field strength not only the increasing signal but also the extended spectral resolution was advantageous for such kind of studies. The difficulties/limitations of ultra high field MRS were also investigated. In the last part of the presented work detection limits of iron labeled stem cells in vivo using magnetic resonance imaging were explored. The studies provided very useful benchmarks for future researchers in terms of the number of labeled stem cells that are required for high-field MRI studies. Overall this work has shown many of the benefits and the areas that need special attention of ultra high fields in MR. Three topics in MRI, MRS and MRSI were

  6. Magnetic resonance imaging and spectroscopy at ultra high fields

    Energy Technology Data Exchange (ETDEWEB)

    Neuberger, Thomas

    2009-06-23

    The goal of the work presented in this thesis was to explore the possibilities and limitations of MRI / MRS using an ultra high field of 17.6 tesla. A broad range of specific applications and MR methods, from MRI to MRSI and MRS were investigated. The main foci were on sodium magnetic resonance spectroscopic imaging of rodents, magnetic resonance spectroscopy of the mouse brain, and the detection of small amounts of iron labeled stem cells in the rat brain using MRI Sodium spectroscopic imaging was explored since it benefits tremendously from the high magnetic field. Due to the intrinsically low signal in vivo, originating from the low concentrations and short transverse relaxation times, only limited results have been achieved by other researchers until now. Results in the literature include studies conducted on large animals such as dogs to animals as small as rats. No studies performed on mice have been reported, despite the fact that the mouse is the most important laboratory animal due to the ready availability of transgenic strains. Hence, this study concentrated on sodium MRSI of small rodents, mostly mice (brain, heart, and kidney), and in the case of the brain on young rats. The second part of this work concentrated on proton magnetic resonance spectroscopy of the rodent brain. Due to the high magnetic field strength not only the increasing signal but also the extended spectral resolution was advantageous for such kind of studies. The difficulties/limitations of ultra high field MRS were also investigated. In the last part of the presented work detection limits of iron labeled stem cells in vivo using magnetic resonance imaging were explored. The studies provided very useful benchmarks for future researchers in terms of the number of labeled stem cells that are required for high-field MRI studies. Overall this work has shown many of the benefits and the areas that need special attention of ultra high fields in MR. Three topics in MRI, MRS and MRSI were

  7. Comparison of ultra high performance supercritical fluid chromatography, ultra high performance liquid chromatography, and gas chromatography for the separation of synthetic cathinones.

    Science.gov (United States)

    Carnes, Stephanie; O'Brien, Stacey; Szewczak, Angelica; Tremeau-Cayel, Lauriane; Rowe, Walter F; McCord, Bruce; Lurie, Ira S

    2017-09-01

    A comparison of ultra high performance supercritical fluid chromatography, ultra high performance liquid chromatography, and gas chromatography for the separation of synthetic cathinones has been conducted. Nine different mixtures of bath salts were analyzed in this study. The three different chromatographic techniques were examined using a general set of controlled synthetic cathinones as well as a variety of other synthetic cathinones that exist as positional isomers. Overall 35 different synthetic cathinones were analyzed. A variety of column types and chromatographic modes were examined for developing each separation. For the ultra high performance supercritical fluid chromatography separations, analyses were performed using a series of Torus and Trefoil columns with either ammonium formate or ammonium hydroxide as additives, and methanol, ethanol or isopropanol organic solvents as modifiers. Ultra high performance liquid chromatographic separations were performed in both reversed phase and hydrophilic interaction chromatographic modes using SPP C18 and SPP HILIC columns. Gas chromatography separations were performed using an Elite-5MS capillary column. The orthogonality of ultra high performance supercritical fluid chromatography, ultra high performance liquid chromatography, and gas chromatography was examined using principal component analysis. For the best overall separation of synthetic cathinones, the use of ultra high performance supercritical fluid chromatography in combination with gas chromatography is recommended. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Ultra-high current density thin-film Si diode

    Science.gov (United States)

    Wang, Qi [Littleton, CO

    2008-04-22

    A combination of a thin-film .mu.c-Si and a-Si:H containing diode structure characterized by an ultra-high current density that exceeds 1000 A/cm.sup.2, comprising: a substrate; a bottom metal layer disposed on the substrate; an n-layer of .mu.c-Si deposited the bottom metal layer; an i-layer of .mu.c-Si deposited on the n-layer; a buffer layer of a-Si:H deposited on the i-layer, a p-layer of .mu.c-Si deposited on the buffer layer; and a top metal layer deposited on the p-layer.

  9. Achieving Mixtures of Ultra-High Performance Concrete

    Directory of Open Access Journals (Sweden)

    Mircea POPA

    2013-07-01

    Full Text Available Ultra-High Performance Concrete (UHPC is a relatively new concrete. According to [11] UHPC is that concrete which features compressive strength over C100/115 class. Up to this point standards for this type of concrete were not adopted, although its characteristic strength exceeds those specified in [33]. Its main property is high compressive strength. This provides the possibility of reducing the section of elements (beams or columns made of this type of concrete, while the load capacity remains high. The study consists in blending mixtures of UHPC made of varying proportions of materials. The authors have obtained strengths of up to 160 MPa. The materials used are: Portland cement, silica fume, quartz powder, steel fibers, superplasticiser, sand and crushed aggregate for concrete - andesite.

  10. Evaluation of ISABELLE full cell ultra high vacuum system

    International Nuclear Information System (INIS)

    Foerster, C.L.; Briggs, J.; Chou, T.S.; Stattel, P.

    1980-01-01

    The ISABELLE Full Cell Vacuum System consisting of a 40 m long, by 8.8 cm diameter stainless steel tube pumped by seven pumping stations was assembled and processed for 10 -12 Torr operation. Evaluation and testing of the system and its sub-assemblies has been completed. Detail design of system components and the determination of the conditioning process was completed. The best procedure to rough pump, leak test, vacuum bake the system, condition pumps, degas gauges, turn on ion pumps and flash sublimation pumps was established. Pressures below 2 x 10 -11 Torr are now routinely achieved in normal operation of the Full Cell. This includes pump down after replacement of various components and pump down after back fill with moist unfiltered air. The techniques developed for the Full Cell will be used to build the ISABELLE Ultra High Vacuum System

  11. Ultra-high-ohmic microstripline resistors for Coulomb blockade devices

    International Nuclear Information System (INIS)

    Lotkhov, Sergey V

    2013-01-01

    In this paper, we report on the fabrication and low-temperature characterization of ultra-high-ohmic microstripline resistors made of a thin film of weakly oxidized titanium. Nearly linear voltage–current characteristics were measured at temperatures down to T ∼ 20 mK for films with sheet resistivities as high as ∼7 kΩ, i.e. about an order of magnitude higher than our previous findings for weakly oxidized Cr. Our analysis indicates that such an improvement can help to create an advantageous high-impedance environment for different Coulomb blockade devices. Further properties of the Ti film addressed in this work show the promise of low-noise behavior of the resistors when applied in different realizations of the quantum standard of current. (paper)

  12. Active Galactic Nuclei: Sources for ultra high energy cosmic rays?

    International Nuclear Information System (INIS)

    Biermann, Peter L.; Becker, Julia K.; Caramete, Laurentiu; Curutiu, Alex; Engel, Ralph; Falcke, Heino; Gergely, Laszlo A.; Isar, P. Gina; Maris, Ioana C.; Meli, Athina; Kampert, Karl-Heinz; Stanev, Todor; Tascau, Oana; Zier, Christian

    2009-01-01

    The origin of ultra high energy cosmic rays promises to lead us to a deeper understanding of the structure of matter. This is possible through the study of particle collisions at center-of-mass energies in interactions far larger than anything possible with the Large Hadron Collider, albeit at the substantial cost of no control over the sources and interaction sites. For the extreme energies we have to identify and understand the sources first, before trying to use them as physics laboratories. Here we describe the current stage of this exploration. The most promising contenders as sources are radio galaxies and gamma ray bursts. The sky distribution of observed events yields a hint favoring radio galaxies. Key in this quest are the intergalactic and galactic magnetic fields, whose strength and structure are not yet fully understood. Current data and statistics do not yet allow a final judgement. We outline how we may progress in the near future.

  13. Active Galactic Nuclei: Sources for ultra high energy cosmic rays?

    Energy Technology Data Exchange (ETDEWEB)

    Biermann, Peter L. [MPI for Radioastronomy, Bonn (Germany); Dept. of Phys. and Astron., Univ. of Bonn (Germany); Dept. of Phys. and Astr., Univ. of Alabama, Tuscaloosa, AL (United States); Dept. of Phys., Univ. of Alabama at Huntsville, AL (United States); Inst. Nucl. Phys. FZ, Karlsruhe Inst. of Techn. (KIT) (Germany); Becker, Julia K. [Institution foer Fysik, Goeteborgs Univ. (Sweden); Dept. of Phys., Univ. Dortmund, Dortmund (Germany); Caramete, Laurentiu [MPI for Radioastronomy, Bonn (Germany); Institute for Space Studies, Bucharest (Romania); Curutiu, Alex [MPI for Radioastronomy, Bonn (Germany); Engel, Ralph [Inst. Nucl. Phys. FZ, Karlsruhe Inst. of Techn. (KIT) (Germany); Falcke, Heino [Dept. of Astrophys., IMAP, Radboud Univ., Nijmegen (Netherlands); ASTRON, Dwingeloo (Netherlands); Gergely, Laszlo A. [Dept. Appl. Sci., London South Bank University (United Kingdom); Dept. of Theoret. and Exp. Phys., Univ. of Szeged, Szeged (Hungary); Isar, P. Gina [Inst. Nucl. Phys. FZ, Karlsruhe Inst. of Techn. (KIT) (Germany); Institute for Space Studies, Bucharest (Romania); Maris, Ioana C. [Inst. Nucl. Phys. FZ, Karlsruhe Inst. of Techn. (KIT) (Germany); Meli, Athina [Physik. Inst. Univ. Erlangen-Nuernberg (Germany); Kampert, Karl-Heinz [Phys. Dept., Univ. Wuppertal (Germany); Stanev, Todor [Bartol Research Inst., Univ. of Delaware, Newark, DE (United States); Tascau, Oana [Phys. Dept., Univ. Wuppertal (Germany); Zier, Christian [MPI for Radioastronomy, Bonn (Germany); Raman Res. Inst., Bangalore (India)

    2009-05-15

    The origin of ultra high energy cosmic rays promises to lead us to a deeper understanding of the structure of matter. This is possible through the study of particle collisions at center-of-mass energies in interactions far larger than anything possible with the Large Hadron Collider, albeit at the substantial cost of no control over the sources and interaction sites. For the extreme energies we have to identify and understand the sources first, before trying to use them as physics laboratories. Here we describe the current stage of this exploration. The most promising contenders as sources are radio galaxies and gamma ray bursts. The sky distribution of observed events yields a hint favoring radio galaxies. Key in this quest are the intergalactic and galactic magnetic fields, whose strength and structure are not yet fully understood. Current data and statistics do not yet allow a final judgement. We outline how we may progress in the near future.

  14. Micro-damage propagation in ultra-high vacuum seals

    CERN Document Server

    Lutkiewicz, P; Garion, C

    2010-01-01

    The paper addresses a fundamental problem of tightness of ultra-high vacuum systems (UHV) at cryogenic temperatures in the light of continuum damage mechanics (CDM). The problem of indentation of a rigid punch into an elastic-plastic half-space is investigated based on rate independent plasticity with mixed kinematic and isotropic hardening. The micro-damage fields are modeled by using an anisotropic approach with a kinetic law of damage evolution suitable for ductile materials and cryogenic temperatures. The model has been experimentally validated and the results are used to predict the onset of macro-cracking (loss of tightness) and the corresponding load (contact pressure). The algorithm is applied in the design of UHV systems for particle accelerators. (C) 2009 Published by Elsevier Ltd.

  15. Ultra high energy electrons powered by pulsar rotation.

    Science.gov (United States)

    Mahajan, Swadesh; Machabeli, George; Osmanov, Zaza; Chkheidze, Nino

    2013-01-01

    A new mechanism of particle acceleration, driven by the rotational slow down of the Crab pulsar, is explored. The rotation, through the time dependent centrifugal force, can efficiently excite unstable Langmuir waves in the electron-positron (hereafter e(±)) plasma of the star magnetosphere. These waves, then, Landau damp on electrons accelerating them in the process. The net transfer of energy is optimal when the wave growth and the Landau damping times are comparable and are both very short compared to the star rotation time. We show, by detailed calculations, that these are precisely the conditions for the parameters of the Crab pulsar. This highly efficient route for energy transfer allows the electrons in the primary beam to be catapulted to multiple TeV (~ 100 TeV) and even PeV energy domain. It is expected that the proposed mechanism may, unravel the puzzle of the origin of ultra high energy cosmic ray electrons.

  16. Cosmic-ray ultra high-energy multijet family event

    International Nuclear Information System (INIS)

    Zou Bao-tang; Wang Cheng-rui; Ren Jing-ru

    1987-01-01

    A cosmic-ray ultra-high-energy multijet family event with visible energy of about 1500 TeV and five large cores is reported. This event was found in the 1980-1981 exposure of the Mt. Kambala (5500 M a.s.l.) emulsion-chamber experiment. The family characteristics are analyzed and compared with other cosmic ray events in the same energy range. The production and fragmentation characteristics of the five jets are studied and compared with the experimental results of accelerators and emulsion chamber C-jets as well as with QCD predictions above the TeV range. Some features on hadronic interactions in the TeV range are discussed

  17. Ultra-high-speed inversion recovery echo planar MR imaging

    International Nuclear Information System (INIS)

    Stehling, M.K.; Ordidge, R.J.; Coxon, R.; Chapman, B.; Houseman, A.M.; Guifoyle, D.; Blamire, A.; Gibbs, P.; Mansfield, P.

    1988-01-01

    Fast two-dimensional FT MR imaging techniques such as fast low-angle shot do not allow inversion recovery (IR). Rapid repetition of low-angle pulses is incompatible with a 180 0 inversion pulse. Echo planar imaging (EPI) can be applied in conjunction with IR, because after preparation of the spin system, a complete image is acquired. Data acquisition in less than 100 msec and real-time display allows interactive optimization of inversion time (4.0-9,000 msec) with little time penalty. The authors have applied IR EPI to the study of the brain, liver, and kidneys in normal volunteers and patients. Technical details are presented, and the applications of this first ultra-high-speed IR technique will be shown

  18. Ultra High Fluence Radiation Monitoring Technology for the Future Circular Collider at CERN

    CERN Document Server

    Gorine, Georgi; Mandic, Igor; Jazbec, Anže; Snoj, Luka; Capeans, Mar; Moll, Michael; Bouvet, Didier; Ravotti, Federico; Sallese, Jean-Michel

    2018-01-01

    The Future Circular Collider (FCC) is foreseen as the next generation ~100 km long synchrotron to be built in the Geneva area starting 2050. This machine is expected to reach an energy level of 100 TeV generating unprecedented radiation levels >100 times higher than in today`s Large Hadron Collider (LHC). Current Radiation Monitoring system, like the RADMONs employed in the LHC, will not be capable to function and withstand this harsh environment. The development of a new Ultra High Fluence and Dose Radiation Sensor is a key element to allow irradiation tests of FCC equipment and, at a later stage, to monitor radiation levels in the FCC itself. In this paper, we present an innovative dosimetry solution based on thin layers of metals, which resistivity is shown to increase significantly due to the accumulated displacement damage. After describing the fabrication techniques used to manufacture these Radiation Dependent Resistors (RDR), we show and discuss the results of the irradiation experiments carried out ...

  19. Irradiation of carbon nanotubes with carbon projectiles: A molecular dynamics study

    Energy Technology Data Exchange (ETDEWEB)

    Denton, Cristian D. [Departamento de Fisica Aplicada, Universidad de Alicante, 03080 Alicante (Spain); Heredia-Avalos, Santiago; Moreno-Marin, Juan Carlos [Departamento de Fisica, Ingenieria de Sistemas y Teoria de la Senal, Universidad de Alicante, 03080 Alicante (Spain)

    2013-04-15

    The irradiation of carbon based nanostructures with ions and electrons has been shown to be an appropriate tool to tailor their properties. The defects induced in the nanostructures during irradiation are able to modify their mechanical and electronic properties. Here we simulate the irradiation of carbon nanotubes with carbon ions using a molecular dynamics code. We use the Tersoff potential joined smoothly to the Universal Ziegler-Biersack-Littmark potential at short distances. We study the number of defects produced after irradiation with a single carbon ion finding a saturation with its energy at {proportional_to} 3 keV. We observe, after continuum irradiation with low energy ions, the formation of bumps in the irradiated region. For larger energy ions we find that the diameter of the nanotube shrinks as shown in previous works. (copyright 2013 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  20. Induction and reversion process of molecular and cytological alterations after highly irradiated food ingestion in mice

    International Nuclear Information System (INIS)

    Rojo M, M.I.; Fernandez C, M.

    1984-01-01

    The molecular and cytological alterations induced in a mammal (Mus musculus) fed ad libitum with a balanced pellet diet irradiated with 50 KGy gamma radiation from weaning, for different periods, are analyzed. The transient chromosomal changes that recall tumor-like phenomena could be the expression of the damage and repair processes induced by changed molecules present in irradiated food. The reversible alterations of DNA structure and cytoplasmatic soluble proteins observed in mice fed with irradiated pellet diet could be interpreted as a result of the enhancement of the repair processes which could also explain the significant increase of the radioresistance of DNA found at 200 days after irradiated food ingestion. Finally, our results would suggest an induction of a pseudo-neoplasia due to a prolongated and exclusive ingestion of food irradiated with sterilizing gamma dose. Moreover, the maintenance of the irradiated diet induce the reversion of the observed phenomena by an eventual activation of the repair mechanisms. (Author)

  1. Detection of irradiated food by the changes in protein molecular mass distribution

    International Nuclear Information System (INIS)

    Niciforovic, A.; Radojcic, M.; Milosavljevic, B.H.

    1998-01-01

    Complete text of publication follows. The present work deals with the radiation-induced damage of proteins, which is followed by the change in the molecular mass. The phenomenon was studied on protein rich samples, i.e., chicken meat and dehydrated egg white. The radiation dose applied was in the range of the ones used for food microbial control. Chicken drumstick and chicken white meat proteins were separated according to their molecular mass. The protein profile was compared to the meat samples irradiated in the frozen state with 5 kGy at 60 Co source. In the case of chicken white meat, irradiation produces both nonselective protein scission (e.g. the amount of proteins of molecular mass larger than 30 kDa decreases, while the amount of proteins of molecular mass smaller than 30 kDa increases), and selective protein scission (e.g. appearance of a protein fragment of molecular mass equal to 18 kDa). In the case of chicken drumstick proteins the irradiation induces both the protein scission and the aggregation. The changes are nonspecific as well as specific and the generation of Mm = 18 kDa protein fragment was observed again. Irradiation of aerated dehydrated egg white proteins produces only nonselective protein scission. The results are discussed in view of the routine application of SDS-PAGE method for the detection of irradiated foodstuff

  2. Ultra-high energy cosmic rays and prompt TeV gamma rays from ...

    Indian Academy of Sciences (India)

    physics pp. 789-792. Ultra-high energy cosmic rays and prompt. TeV gamma rays from gamma ray bursts ... The origin of the observed ultra-high energy cosmic ray (UHECR) events with ... are proton and electron rest mass, respectively.

  3. 75 FR 81284 - Nationwide Use of High Frequency and Ultra High Frequency Active SONAR Technology; Draft...

    Science.gov (United States)

    2010-12-27

    ... Frequency and Ultra High Frequency Active SONAR Technology; Draft Programmatic Environmental Assessment and... Programmatic Environmental Assessment (PEA) for the Nationwide Use of High Frequency (HF) and Ultra High... potential impacts of each alternative on the human and natural environments. DATES: Comments and related...

  4. Ultra high performance concrete made with rice husk ash for reduced autogenous shrinkage

    NARCIS (Netherlands)

    Van Breugel, K.; Van Tuan, N.

    2014-01-01

    Ultra High Strength Concrete (UHPC) is generally made with low w/c mixtures and by adding silica fume. Low w/c mixtures, however, exhibit high autogenous shrinkage, while a high amount of silica fume increases the price of these mixtures. For designing ultra high strength mixtures with low

  5. Ultra-high field MRI: Advancing systems neuroscience towards mesoscopic human brain function

    NARCIS (Netherlands)

    Dumoulin, Serge O; Fracasso, A.; Van der Zwaag, W.; Siero, Jeroen C W; Petridou, Natalia

    2018-01-01

    Human MRI scanners at ultra-high magnetic field strengths of 7 T and higher are increasingly available to the neuroscience community. A key advantage brought by ultra-high field MRI is the possibility to increase the spatial resolution at which data is acquired, with little reduction in image

  6. MHD Modeling of Conductors at Ultra-High Current Density

    International Nuclear Information System (INIS)

    ROSENTHAL, STEPHEN E.; DESJARLAIS, MICHAEL P.; SPIELMAN, RICK B.; STYGAR, WILLIAM A.; ASAY, JAMES R.; DOUGLAS, M.R.; HALL, C.A.; FRESE, M.H.; MORSE, R.L.; REISMAN, D.B.

    2000-01-01

    In conjunction with ongoing high-current experiments on Sandia National Laboratories' Z accelerator, the authors have revisited a problem first described in detail by Heinz Knoepfel. Unlike the 1-Tesla MITLs of pulsed power accelerators used to produce intense particle beams, Z's disc transmission line (downstream of the current addition) is in a 100--1,200 Tesla regime, so its conductors cannot be modeled simply as static infinite conductivity boundaries. Using the MHD code MACH2 they have been investigating the conductor hydrodynamics, characterizing the joule heating, magnetic field diffusion, and material deformation, pressure, and velocity over a range of current densities, current rise-times, and conductor materials. Three purposes of this work are (1) to quantify power flow losses owing to ultra-high magnetic fields, (2) to model the response of VISAR diagnostic samples in various configurations on Z, and (3) to incorporate the most appropriate equation of state and conductivity models into the MHD computations. Certain features are strongly dependent on the details of the conductivity model

  7. Application of ultra high pressure (UHP) in starch chemistry.

    Science.gov (United States)

    Kim, Hyun-Seok; Kim, Byung-Yong; Baik, Moo-Yeol

    2012-01-01

    Ultra high pressure (UHP) processing is an attractive non-thermal technique for food treatment and preservation at room temperature, with the potential to achieve interesting functional effects. The majority of UHP process applications in food systems have focused on shelf-life extension associated with non-thermal sterilization and a reduction or increase in enzymatic activity. Only a few studies have investigated modifications of structural characteristics and/or protein functionalities. Despite the rapid expansion of UHP applications in food systems, limited information is available on the effects of UHP on the structural and physicochemical properties of starch and/or its chemical derivatives included in most processed foods as major ingredients or minor additives. Starch and its chemical derivatives are responsible for textural and physical properties of food systems, impacting their end-use quality and/or shelf-life. This article reviews UHP processes for native (unmodified) starch granules and their effects on the physicochemical properties of UHP-treated starch. Furthermore, functional roles of UHP in acid-hydrolysis, hydroxypropylation, acetylation, and cross-linking reactions of starch granules, as well as the physicochemical properties of UHP-assisted starch chemical derivatives, are discussed.

  8. Fracture toughness of ultra high performance concrete by flexural performance

    Directory of Open Access Journals (Sweden)

    Manolova Emanuela

    2016-01-01

    Full Text Available This paper describes the fracture toughness of the innovative structural material - Ultra High Performance Concrete (UHPC, evaluated by flexural performance. For determination the material behaviour by static loading are used adapted standard test methods for flexural performance of fiber-reinforced concrete (ASTM C 1609 and ASTM C 1018. Fracture toughness is estimated by various deformation parameters derived from the load-deflection curve, obtained by testing simple supported beam under third-point loading, using servo-controlled testing system. This method is used to be estimated the contribution of the embedded fiber-reinforcement into improvement of the fractural behaviour of UHPC by changing the crack-resistant capacity, fracture toughness and energy absorption capacity with various mechanisms. The position of the first crack has been formulated based on P-δ (load- deflection response and P-ε (load - longitudinal deformation in the tensile zone response, which are used for calculation of the two toughness indices I5 and I10. The combination of steel fibres with different dimensions leads to a composite, having at the same time increased crack resistance, first crack formation, ductility and post-peak residual strength.

  9. Some aspects of ultra high energy gamma ray astronomy

    International Nuclear Information System (INIS)

    De Jager, O.C.

    1983-11-01

    A short review of ultra high energy (UHE) gamma ray astronomy (10 11 14 eV) as well as a description of a planned experiment to be erected at Potchefstroom is given in the introduction. This experiment will be the first and only one in the Southern Hemisphere and as such may play an important role in this new field of astronomy and astrophysics. In the first part the necessary infrastructure for astronomical observations of known celestial objects is developed. This embodies the special physical, mechanical and astronomical constraints in this type of astronomy, such as the definition of the various astronomical coordinate systems and transformations between them, the effect of precession and nutation on the source position etc. This leads to automatic observation schedules for the various applicable techniques of observation. In the second part the various effects which may influence the arrival time of a gamma ray at the telescope is investigated. It is found that dispersion and relativistic effects are negligible, given the special type of analysis used in this low counting rate system. The classic Doppler effect due to the motion of Earth as well as the configuration of the telescope does have a major effect and must be taken into consideration when analysing the data. A simple method, depending only on the movement of Earth around the sun, is developed to simplify the identification of pulsars at the planned observatory where computing facilities are limited

  10. A new generation of ultra high strength steel pipelines

    International Nuclear Information System (INIS)

    Brozda, J.; Zeman, M.; Weglowski, M.

    2008-01-01

    For many years an increased demand for natural gas can be observed. Ultra high-strength pipelines with higher operating pressures and/or reduced wall thickness are a means to reduce transmission costs. Motivated by reduced investment costs (overcharge a few billion of dollars), tend towards the development of a new grade of pipeline steel with microalloying element for example Nb, that potentially lowers the total cost of long-distance gas pipelines by 5 - 15%. New long distance pipelines have budgets in excess of several billion dollars. This paper describes mechanical properties of new generation of pipelines steel with higher content of niobium and the influence the welding thermal cycles on the microstructure and brittle fracture resistance. The resistance to cold cracking has also been determined. It was found that the new steel has close properties to API X70 grade steels, but is cheaper in manufacturing and installation. The steel has been covered by the amended EN 10028-5 standard and proper modifications will also be made in other European standards. (author)

  11. SLC polarized beam source ultra-high-vacuum design

    International Nuclear Information System (INIS)

    Lavine, T.L.; Clendenin, J.E.; Garwin, E.L.; Hoyt, E.W.; Hoyt, M.W.; Miller, R.H.; Nuttall, J.A.; Schultz, D.C.; Wright, D.

    1991-05-01

    This paper describes the design of the ultra-high vacuum system for the beam-line from the 160-kV polarized electron gun to the linac injector in the Stanford Linear Collider (SLC). The polarized electron source is a GaAs photocathode, requiring 10 -11 -Torr-range pressure for adequate quantum efficiency and longevity. The photo-cathode is illuminated by 3-nsec-long laser pulses. Photo-cathode maintenance and improvements require occasional substitution of guns with rapid restoration of UHV conditions. Differential pumping is crucial since the pressure in the injector is more than 10 times greater than the photocathode can tolerate, and since electron-stimulated gas desorption from beam loss in excess of 0.1% of the 20-nC pulses may poison the photocathode. Our design for the transport line contains a differential pumping region isolated by a pair of valves. Exchange of guns requires venting only this isolated region which can be restored to UHV rapidly by baking. The differential pumping is performed by non-evaporable getters (NEGs) and an ion pump. 3 refs., 3 figs

  12. Fibrous Fillers to Manufacture Ultra High Ash/Performance Paper

    Energy Technology Data Exchange (ETDEWEB)

    Dr. VIjay K. Mathur

    2009-04-30

    The paper industry is one of the largest users of energy and emitters of CO2 in the US manufacturing industry. In addition to that, it is facing tremendous financial pressure due to lower cost imports. The fine paper industry has shrunk from 15 million tons per year production to 10 million tons per year in the last 5 years. This has resulted in mill closures and job loses. The AF&PA and the DOE formed a program called Agenda 2020 to help in funding to develop breakthrough technologies to provide help in meeting these challenges. The objectives of this project were to optimize and scale-up Fibrous Fillers technology, ready for commercial deployment and to develop ultra high ash/high performance paper using Fibrous Fillers. The goal was to reduce energy consumption, carbon footprint, and cost of manufacturing paper and related industries. GRI International (GRI) has been able to demonstrate the techno - economic feasibility and economic advantages of using its various products in both handsheets as well as in commercial paper mills. GRI has also been able to develop sophisticated models that demonstrate the effect of combinations of GRI's fillers at multiple filler levels. GRI has also been able to develop, optimize, and successfully scale-up new products for use in commercial paper mills.

  13. Evaluation of Ultra-High Temperature Ceramics for Aeropropulsion Use

    Science.gov (United States)

    Levine, Stanley R.; Opila, Elizabeth J.; Halbig, Michael C.; Kiser, James D.; Singh, Mrityunjay; Salem, Jonathan A.

    2001-01-01

    Among the ultra-high temperature ceramics (UHTC) are a group of materials consisting of zirconium diboride or hafnium diboride plus silicon carbide, and in some instances, carbon. These materials offer a good combination of properties that make them candidates for airframe leading edges on sharp-bodied reentry vehicles. These UHTC perform well in the environment for such applications, i.e., air at low pressure. The purpose of this study was to examine three of these materials under conditions more representative of a propulsion environment, i.e., higher oxygen partial pressure and total pressure. Results of strength and fracture toughness measurements, furnace oxidation and high velocity thermal shock exposures are presented for ZrB2 plus 20 volume % SiC, ZrB2 plus 14 volume % SiC plus 30 volume % C, and SCS-9a SiC fiber reinforced ZrB2 plus 20 volume % SiC. The poor oxidation resistance of UHTCs is the predominant factor limiting their applicability to propulsion applications.

  14. Ultra high resolution soft x-ray tomography

    International Nuclear Information System (INIS)

    Haddad, W.S.; Trebes, J.E.; Goodman, D.M.; Lee, H.R.; McNulty, I.; Zalensky, A.O.

    1995-01-01

    Ultra high resolution three dimensional images of a microscopic test object were made with soft x-rays using a scanning transmission x-ray microscope. The test object consisted of two different patterns of gold bars on silicon nitride windows that were separated by ∼5 microm. A series of nine 2-D images of the object were recorded at angles between -50 to +55 degrees with respect to the beam axis. The projections were then combined tomographically to form a 3-D image by means of an algebraic reconstruction technique (ART) algorithm. A transverse resolution of ∼ 1,000 angstrom was observed. Artifacts in the reconstruction limited the overall depth resolution to ∼ 6,000 angstrom, however some features were clearly reconstructed with a depth resolution of ∼ 1,000 angstrom. A specially modified ART algorithm and a constrained conjugate gradient (CCG) code were also developed as improvements over the standard ART algorithm. Both of these methods made significant improvements in the overall depth resolution, bringing it down to ∼ 1,200 angstrom overall. Preliminary projection data sets were also recorded with both dry and re-hydrated human sperm cells over a similar angular range

  15. Ultra high resolution soft x-ray tomography

    International Nuclear Information System (INIS)

    Haddad, W.S.; Trebes, J.E.; Goodman, D.M.

    1995-01-01

    Ultra high resolution three dimensional images of a microscopic test object were made with soft x-rays using a scanning transmission x-ray microscope. The test object consisted of two different patterns of gold bars on silicon nitride windows that were separated by ∼5μm. A series of nine 2-D images of the object were recorded at angles between -50 to +55 degrees with respect to the beam axis. The projections were then combined tomographically to form a 3-D image by means of an algebraic reconstruction technique (ART) algorithm. A transverse resolution of ∼1000 Angstrom was observed. Artifacts in the reconstruction limited the overall depth resolution to ∼6000 Angstrom, however some features were clearly reconstructed with a depth resolution of ∼1000 Angstrom. A specially modified ART algorithm and a constrained conjugate gradient (CCG) code were also developed as improvements over the standard ART algorithm. Both of these methods made significant improvements in the overall depth resolution bringing it down to ∼1200 Angstrom overall. Preliminary projection data sets were also recorded with both dry and re-hydrated human sperm cells over a similar angular range

  16. An ultra-high speed whole slide image viewing system.

    Science.gov (United States)

    Yagi, Yukako; Yoshioka, Shigeatsu; Kyusojin, Hiroshi; Onozato, Maristela; Mizutani, Yoichi; Osato, Kiyoshi; Yada, Hiroaki; Mark, Eugene J; Frosch, Matthew P; Louis, David N

    2012-01-01

    One of the goals for a Whole Slide Imaging (WSI) system is implementation in the clinical practice of pathology. One of the unresolved problems in accomplishing this goal is the speed of the entire process, i.e., from viewing the slides through making the final diagnosis. Most users are not satisfied with the correct viewing speeds of available systems. We have evaluated a new WSI viewing station and tool that focuses on speed. A prototype WSI viewer based on PlayStation®3 with wireless controllers was evaluated at the Department of Pathology at MGH for the following reasons: 1. For the simulation of signing-out cases; 2. Enabling discussion at a consensus conference; and 3. Use at slide seminars during a Continuing Medical Education course. Pathologists were being able to use the system comfortably after 0-15 min training. There were no complaints regarding speed. Most pathologists were satisfied with the functionality, usability and speed of the system. The most difficult situation was simulating diagnostic sign-out. The preliminary results of adapting the Sony PlayStation®3 (PS3®) as an ultra-high speed WSI viewing system were promising. The achieved speed is consistent with what would be needed to use WSI in daily practice.

  17. MHD Modeling of Conductors at Ultra-High Current Density

    International Nuclear Information System (INIS)

    Rosenthal, S.E.; Asay, J.R.; Desjarlais, M.P.; Douglas, M.R.; Frese, M.H.; Hall, C.A.; Morse, R.L.; Reisman, D.; Spielman, R.B.; Stygar, W.A.

    1999-01-01

    In conjunction with ongoing high-current experiments on Sandia National Laboratories' Z accelerator we have revisited a problem first described in detail by Heinz Knoepfel. MITLs of previous pulsed power accelerators have been in the 1-Tesla regime. Z's disc transmission line (downstream of the current addition) is in a 100-1200 Tesla regime, so its conductors cannot be modeled simply as static infinite conductivity boundaries. Using the MHD code MACH2 we have been investigating conductor hydrodynamics, characterizing the joule heating, magnetic field diffusion, and material deformation, pressure, and velocity over a range of current densities, current rise-times, and conductor materials. Three purposes of this work are ( 1) to quantify power flow losses owing to ultra-high magnetic fields, (2) to model the response of VISAR diagnostic samples in various configurations on Z, and (3) to incorporate the most appropriate equation of state and conductivity models into our MHD computations. Certain features are strongly dependent on the details of the conductivity model. Comparison with measurements on Z will be discussed

  18. Vacuum improvements for ultra high charge state ion acceleration

    International Nuclear Information System (INIS)

    Xie, Z.Q.; Lyneis, C.M.; Clark, D.J.; Guy, A.; Lundgren, S.A

    1998-06-01

    The installation of a second cryo panel has significantly improved the vacuum in the 88-Inch Cyclotron at Lawrence Berkeley National Laboratory. The neutral pressure in the extraction region decreased from 1.2 x 10 -6 down to about 7 x 10 -7 Torr. The vacuum improvement reduces beam loss from charge changing collisions and enhances the cyclotron beam transmission, especially for the high charge state heavy ions. Tests with improved vacuum show the cyclotron transmission increased more than 50% (from 5.7% to 9.0%) for a Xe 27+ at 603 MeV, more than doubled for a Bi 41+ beam (from 1.9% to 4.6%) at 904 MeV and tripled for a U 47+ beam (from 1.2% to 3.6%) at 1,115 MeV. At about 5 NeV/nucleon 92 enA (2.2 pnA) for Bi 41+ and 14 enA (0.3 pnA) for U 47+ were extracted ut of the 88-Inch Cyclotron Ion beams with charge states as high as U 64+ have been produced by the LBNL AECR-U ion source and accelerated through the cyclotron for the first time. The beam losses for a variety of ultra high charge state ions were measured as a function of cyclotron pressure and compared with the calculations from the existing models

  19. Vacuum improvements for ultra high charge state ion acceleration

    International Nuclear Information System (INIS)

    Xie, Z.Q.; Lyneis, C.M.; Clark, D.J.; Guy, A.; Lundgren, S.A.

    1999-01-01

    The installation of a second cryo panel has significantly improved the vacuum in the 88-Inch Cyclotron at Lawrence Berkeley National Laboratory. The neutral pressure in the extraction region decreased from 1.2 x 10 -6 down to about 7 x 10 -7 Torr. The vacuum improvement reduces beam loss from charge changing collisions and enhances the cyclotron beam transmission, especially for the high charge state heavy ions. Tests with improved vacuum show the cyclotron transmission increased more than 50% (from 5.7% to 9.0%) for a Xe 27+ at 603 MeV, more than doubled for a Bi 41+ beam (from 1.9% % to 4.6%) at 904 MeV and tripled for a U 47+ beam (from 1.2% to 3.6%) at 1115 MeV. At about 5 MeV/nucleon 92 enA (2.2 pnA) for Bi 41+ and 14 enA (0.3 pnA) for U 47+ were extracted out of the 88-Inch Cyclotron Ion beams with charge states as high as U 64+ have been produced by the LBNL AECR-U ion source and accelerated through the cyclotron for the first time. The beam losses for a variety of ultra high charge state ions were measured as a function of cyclotron pressure and compared with the calculations from the existing models. (authors)

  20. Ultra high frequency induction welding of powder metal compacts

    Directory of Open Access Journals (Sweden)

    Çavdar, Uǧur

    2014-06-01

    Full Text Available The application of the iron based Powder Metal (PM compacts in Ultra High Frequency Induction Welding (UHFIW were reviewed. These PM compacts are used to produce cogs. This study investigates the methods of joining PM materials enforceability with UHFIW in the industry application. Maximum stress and maximum strain of welded PM compacts were determined by three point bending and strength tests. Microhardness and microstructure of induction welded compacts were determined.Soldadura por inducción de ultra alta frecuencia de polvos de metal compactados. Se ha realizado un estudio de la aplicación de polvos de metal (PM de base hierro compactados por soldadura por inducción de ultra alta frecuencia (UHFIW. Estos polvos de metal compactados se utilizan para producir engranajes. Este estudio investiga los métodos de uni.n de los materiales de PM con UHFIW en su aplicación en la industria. La máxima tensión y la máxima deformación de los polvos de metal compactados soldados fueron determinadas por flexión en tres puntos y prueba de resistencia. Se determinó la microdureza y la microestructura de los polvos compactados por soldadura por inducción.

  1. Influences of gamma irradiation treatment on the molecular weight of chitosan

    International Nuclear Information System (INIS)

    Luu Thi Tho; Nguyen Viet Thong; Tran Minh Quynh; Vu Thi Hong Khanh

    2013-01-01

    Effects of gamma radiation on molecular properties of shrimp and squid chitosan (MTV, Vietnam) have been studied with three kind chitosan that having degree of deacetylation 75% and different molecular molecular weight of 69, 187 and 345 kDa, Chitosan samples were irradiated at the same dose rate of 4.3 kGy per hour with various radiation dose of 25, 50, 75, 100, 200 and 500 kGy. The viscosity average molecular weight and degree of deacetylation (DD) of chitosan before and after irradiation have been investigated via their intrinsic viscosity and Furrier transform infra-red (FT-IR). The data revealed the chitosan backbone chains has been degraded by gamma radiation, resulting in the smaller fragments with reduced molecular weight to 3000 Da, whereas their DD have not much changed. (author)

  2. Molecular weight changes induced in an anionic polydimethylsiloxane by gamma irradiation in vacuum

    International Nuclear Information System (INIS)

    Satti, Angel J.; Andreucetti, Noemi A.; Ciolino, Andres E.; Vitale, Cristian; Sarmoria, Claudia; Valles, Enrique M.

    2010-01-01

    An anionic almost monodisperse linear polydimethylsiloxane (PDMS) was subjected to gamma irradiation under vacuum at room temperature. The molecular weight changes induced by the radiation process have been investigated using size exclusion chromatography (SEC) with refraction index (RI) and multi angle laser light scattering (MALLS) detectors, to obtain the number and weight average molecular weights of the irradiated samples. The analysis of the data indicates that crosslinking reactions predominated over scission reactions. The results obtained by an SEC-RI have confirmed the presence of small, but measurable amounts of scission. A previously developed mathematical model of the irradiation process that accounts for simultaneous scission and crosslinking and allows for both H- and Y-crosslinks, fitted well the measured molecular weight data. This prediction is in accordance with the experimental data obtained by 29 Si-Nuclear Magnetic Resonance spectroscopy (NMR) and previously reported data for commercial linear PDMS ().

  3. Effect of low molecular fraction of thymus humoral factor on blood formation processes of irradiated mice

    International Nuclear Information System (INIS)

    Stolyarova, T.V.; Skobel'tsyna, E.S.; Grinberg, S.M.; Kruglikov, I.L.; Korotaev, G.K.; Tepelina, O.M.; Il'ina, T.I.

    1982-01-01

    The effect of low-molecular fraction of thymus humoral factor on blood formation in mice irradiated at 4 Gy was studied. It is shown that injection of low-molecular fraction of thymus hymoral factor to irradiated animals affects proliferative processes in spleen and bone marrow, however the degree of the effect depends on the injection scheme of the preparation. Application of mathematical planning methods of the experiment enables to analyze various injection schemes of low-molecular fraction of thymus humoral factor on the investigated indices. The optimal scheme of preparation injection is determined: 1st injection with the dose of 10 mkg/kg following 4 hour after irradiation, 2d injection - with the same dose in 7-21 days

  4. Molecular exclusion chromatographic analysis on 60Co irradiated rattlesnake

    International Nuclear Information System (INIS)

    Murata, Y.; Rogero, J.R.

    1988-07-01

    Ionizing radiations are sufficiently energetic to be able of breaking chemical bonds and as result of that molecules of substances present in the irradiated will be chemically changed and their biological properties affected also. In this paper the effects of gamma radiation of Co-60 on the rattlesnake venom were studied. A pool of positive crotamina Crotalus durissus terrificus venom was dissolved in 0,15 M NaCl and irradiated with Co-60. Doses of 100, 250, 500, 750, 1500 and 2000 Gy were applied at the dose rate of 1190 Gy/h. With doses over 500 Gy the solutions became turbid, suggesting the presence of aggregates and structural changes of the proteins. The concentration of proteins from the filtered solution was measured by the Lowry method. One ml samples were measured at 230 nm. The partition coefficients and the areas of the three main fraction obtained were calculated. (author) [pt

  5. Molecular Effects of Irradiation (Cobalt-60 on the Control of Panonychus citri (Acari: Tetranychidae

    Directory of Open Access Journals (Sweden)

    Ke Zhang

    2015-11-01

    Full Text Available The effective dose of irradiation to control pest mites in quarantine has been studied extensively, but the molecular mechanisms underlying the effects of the irradiation on mites are largely unknown. In this study, exposure to 400 Gy of γ rays had significant (p < 0.05 effects on the adult survival, fecundity and egg viability of Panonychus citri. The irradiation caused the degradation of the DNA of P. citri adults and damaged the plasma membrane system of the egg, which led to condensed nucleoli and gathered yolk. Additionally, the transcriptomes and gene expression profiles between irradiated and non-irradiated mites were compared, and three digital gene expression libraries were assembled and analyzed. The differentially expressed genes were putatively involved in apoptosis, cell death and the cell cycle. Finally, the expression profiles of some related genes were studied using quantitative real-time PCR. Our study provides valuable information on the changes in the transcriptome of irradiated P. citri, which will facilitate a better understanding of the molecular mechanisms that cause the sterility induced by irradiation.

  6. Ultra-high energy physics and standard basic principles

    Directory of Open Access Journals (Sweden)

    Gonzalez-Mestres Luis

    2014-04-01

    Full Text Available It has not yet been elucidated whether the observed flux suppression for ultra-high energy cosmic rays (UHECR at energies above ≃ 4 x 1019 eV is a signature of the Greisen-Zatsepin-Kuzmin (GZK cutoff or a consequence of other phenomena. In both cases, violations of the standard fundamental principles of Physics can be present and play a significant role. They can in particular modify cosmic-ray interactions, propagation or acceleration at very high energy. Thus, in a long-term program, UHECR data can hopefully be used to test relativity, quantum mechanics, energy and momentum conservation, vacuum properties... as well as the elementariness of standard particles. Data on cosmic rays at energies ≃ 1020 eV may also be sensitive to new physics generated well beyond Planck scale. A typical example is provided by the search for possible signatures of a Lorentz symmetry violation (LSV associated to a privileged local reference frame (the "vacuum rest frame", VRF. If a VRF exists, the internal structure of standard particles at ultra-high energy can undergo substantial modifications. Similarly, the conventional particle symmetries may cease to be valid at such energies instead of heading to a grand unification and the structure of vacuum may no longer be governed by standard quantum field theory. Then, the question whether the notion of Planck scale still makes sense clearly becomes relevant and the very grounds of Cosmology can undergo essential modifications. UHECR studies naturally interact with the interpretation of WMAP and Planck observations. Recent Planck data analyses tend to confirm the possible existence of a privileged space direction. If the observed phenomenon turns out to be a signature of the spinorial space-time (SST we suggested in 1996-97, then conventional Particle Physics may correspond to the local properties of standard matter at low enough energy and large enough distances. This would clearly strengthen the cosmological

  7. Advanced Ultra-High Speed Motor for Drilling

    Energy Technology Data Exchange (ETDEWEB)

    Impact Technologies LLC; University of Texas at Arlington

    2007-03-31

    Three (3) designs have been made for two sizes, 6.91 cm (2.72 inch) and 4.29 cm (1.69 inch) outer diameters, of a patented inverted configured Permanent Magnet Synchronous Machines (PMSM) electric motor specifically for drilling at ultra-high rotational speeds (10,000 rpm) and that can utilize advanced drilling methods. Benefits of these motors are stackable power sections, full control (speed and direction) of downhole motors, flow hydraulics independent of motor operation, application of advanced drilling methods (water jetting and abrasive slurry jetting), and the ability of signal/power electric wires through motor(s). Key features of the final designed motors are: fixed non-rotating shaft with stator coils attached; rotating housing with permanent magnet (PM) rotor attached; bit attached to rotating housing; internal channel(s) in a nonrotating shaft; electric components that are hydrostatically isolated from high internal pressure circulating fluids ('muds') by static metal to metal seals; liquid filled motor with smoothed features for minimized turbulence in the motor during operation; and new inverted coated metal-metal hydrodynamic bearings and seals. PMSM, Induction and Switched Reluctance Machines (SRM), all pulse modulated, were considered, but PMSM were determined to provide the highest power density for the shortest motors. Both radial and axial electric PMSM driven motors were designed with axial designs deemed more rugged for ultra-high speed, drilling applications. The 6.91 cm (2.72 inch) OD axial inverted motor can generate 4.18KW (5.61 Hp) power at 10,000 rpm with a 4 Nm (2.95 ft-lbs) of torque for every 30.48 cm (12 inches) of power section. The 6.91 cm (2.72 inch) OD radial inverted motor can generate 5.03 KW (6.74 Hp) with 4.8 Nm (3.54 ft-lb) torque at 10,000 rpm for every 30.48 cm (12 inches) of power section. The 4.29 cm (1.69 inch) OD radial inverted motor can generate 2.56 KW (3.43 Hp) power with 2.44 Nm (1.8 ft-lb) torque at

  8. Properties of matter at ultra-high densities

    International Nuclear Information System (INIS)

    Banerjee, B.; Chitre, S.M.

    1975-01-01

    The recent discovery of pulsars and their subsequent identification with neutron stars has given a great impetus to the study of the behaviour of matter at ultra high densities. The object of these studies is to calculate the equation of state as a function of density. In this paper, the properties of electrically neutral, cold (T=0) matter at unusually high densities has been reviewed. The physics of the equation of state of such matter divides quite naturally in four density ranges. (i) At the very lowest densities the state of minimum energy is a lattice of 56 Fe atoms. This state persists upto 10 7 g/cm 3 . (ii) In the next density region the nuclei at the lattice sites become neutron rich because the high electron Fermi energy makes inverse beta decay possible. (iii) At a density 4.3 x 10 11 the nuclei become so neutron rich that the neutrons start 'dripping' out of the nuclei and form a gas. This density range is characterised by large, neutron-rich nuclei immersed in a neutron gas. (iv) At a density 2.4 x 10 14 g/cm 3 , the nuclei disappear and a fluid of uniform neutron matter with a small percentage of protons and electrons results. The above four density ranges have been discussed in detail as the equation of state is now well established upto the nuclear density 3 x 10 14 g/cm 3 . The problems of extending the equation of state beyond this density are also touched upon. (author)

  9. On the Origin of Ultra High Energy Cosmic Rays II

    Energy Technology Data Exchange (ETDEWEB)

    Fowler, T K; Colgate, S; Li, H; Bulmer, R H; Pino, J

    2011-03-08

    We show that accretion disks around Active Galactic Nuclei (AGNs) could account for the enormous power in observed ultra high energy cosmic rays {approx}10{sup 20} eV (UHEs). In our model, cosmic rays are produced by quasi-steady acceleration of ions in magnetic structures previously proposed to explain jets around Active Galactic Nuclei with supermassive black holes. Steady acceleration requires that an AGN accretion disk act as a dynamo, which we show to follow from a modified Standard Model in which the magnetic torque of the dynamo replaces viscosity as the dominant mechanism accounting for angular momentum conservation during accretion. A black hole of mass M{sub BH} produces a steady dynamo voltage V {proportional_to} {radical}M{sub BH} giving V {approx} 10{sup 20} volts for M{sub BH} {approx} 10{sup 8} solar masses. The voltage V reappears as an inductive electric field at the advancing nose of a dynamo-driven jet, where plasma instability inherent in collisionless runaway acceleration allows ions to be steadily accelerated to energies {approx} V, finally ejected as cosmic rays. Transient events can produce much higher energies. The predicted disk radiation is similar to the Standard Model. Unique predictions concern the remarkable collimation of jets and emissions from the jet/radiolobe structure. Given MBH and the accretion rate, the model makes 7 predictions roughly consistent with data: (1) the jet length; (2) the jet radius; (3) the steady-state cosmic ray energy spectrum; (4) the maximum energy in this spectrum; (5) the UHE cosmic ray intensity on Earth; (6) electron synchrotron wavelengths; and (7) the power in synchrotron radiation. These qualitative successes motivate new computer simulations, experiments and data analysis to provide a quantitative verification of the model.

  10. Diffuse axonal injury at ultra-high field MRI.

    Directory of Open Access Journals (Sweden)

    Christoph Moenninghoff

    Full Text Available Diffuse axonal injury (DAI is a specific type of traumatic brain injury caused by shearing forces leading to widespread tearing of axons and small vessels. Traumatic microbleeds (TMBs are regarded as a radiological marker for DAI. This study aims to compare DAI-associated TMBs at 3 Tesla (T and 7 T susceptibility weighted imaging (SWI to evaluate possible diagnostic benefits of ultra-high field (UHF MRI.10 study participants (4 male, 6 female, age range 20-74 years with known DAI were included. All MR exams were performed with a 3 T MR system (Magnetom Skyra and a 7 T MR research system (Magnetom 7 T, Siemens AG, Healthcare Sector, Erlangen, Germany each in combination with a 32-channel-receive coil. The average time interval between trauma and imaging was 22 months. Location and count of TMBs were independently evaluated by two neuroradiologists on 3 T and 7 T SWI images with similar and additionally increased spatial resolution at 7 T. Inter- and intraobserver reliability was assessed using the interclass correlation coefficient (ICC. Count and diameter of TMB were evaluated with Wilcoxon signed rank test.Susceptibility weighted imaging revealed a total of 485 TMBs (range 1-190, median 25 at 3 T, 584 TMBs (plus 20%, range 1-262, median 30.5 at 7 T with similar spatial resolution, and 684 TMBs (plus 41%, range 1-288, median 39.5 at 7 T with 10-times higher spatial resolution. Hemorrhagic DAI appeared significantly larger at 7 T compared to 3 T (p = 0.005. Inter- and intraobserver correlation regarding the counted TMB was high and almost equal 3 T and 7 T.7 T SWI improves the depiction of small hemorrhagic DAI compared to 3 T and may be supplementary to lower field strengths for diagnostic in inconclusive or medicolegal cases.

  11. Thermally Induced Ultra High Cycle Fatigue of Copper Alloys of the High Gradient Accelerating Structures

    CERN Document Server

    Heikkinen, Samuli; Wuensch, Walter

    2010-01-01

    In order to keep the overall length of the compact linear collider (CLIC), currently being studied at the European Organization for Nuclear Research (CERN), within reasonable limits, i.e. less than 50 km, an accelerating gradient above 100 MV/m is required. This imposes considerable demands on the materials of the accelerating structures. The internal surfaces of these core components of a linear accelerator are exposed to pulsed radio frequency (RF) currents resulting in cyclic thermal stresses expected to cause surface damage by fatigue. The designed lifetime of CLIC is 20 years, which results in a number of thermal stress cycles of the order of 2.33•1010. Since no fatigue data existed in the literature for CLIC parameter space, a set of three complementary experiments were initiated: ultra high cycle mechanical fatigue by ultrasound, low cycle fatigue by pulsed laser irradiation and low cycle thermal fatigue by high power microwaves, each test representing a subset of the original problem. High conductiv...

  12. Molecular Ultrasound Imaging of Early Vascular Response in Prostate Tumors Irradiated with Carbon Ions

    Directory of Open Access Journals (Sweden)

    Moritz Palmowski

    2009-09-01

    Full Text Available Individualized treatments with combination of radiotherapy and targeted drugs require knowledge about the behavior of molecular targets after irradiation. Angiogenic marker expression has been studied after conventional radiotherapy, but little is known about marker response to charged particles. For the very first time, we used molecular ultrasound imaging to intraindividually track changes in angiogenic marker expression after carbon ion irradiation in experimental tumors. Expression of intercellular adhesion molecule-1 (ICAM-1 and of αvβ3-integrin in subcutaneous AT-1 prostate cancers in rats treated with carbon ions (16 Gy was studied using molecular ultrasound and immunohistochemistry. For this purpose, cyanoacrylate microbubbles were synthesized and linked to specific ligands. The accumulation of targeted microbubbles in tumors was quantified before and 36 hours after irradiation. In addition, tumor vascularization was analyzed using volumetric Doppler ultrasound. In tumors, the accumulation of targeted microbubbles was significantly higher than in nonspecific ones and could be inhibited competitively. Before irradiation, no difference in binding of αvβ3-integrin-specific or ICAM-1-specific microbubbles was observed in treated and untreated animals. After irradiation, however, treated animals showed a significantly higher binding of αvβ3-integrin-specific microbubbles and an enhanced binding of ICAM-1-specific microbubbles than untreated controls. In both groups, a decrease in vascularization occurred during tumor growth, but no significant difference was observed between irradiated and nonirradiated tumors. In conclusion, carbon ion irradiation upregulates ICAM-1 and αvβ3-integrin expression in tumor neovasculature. Molecular ultrasound can indicate the regulation of these markers and thus may help to identify the optimal drugs and time points in individualized therapy regimens.

  13. Physicochemical characterization of irradiated high molecular weight chitosan

    International Nuclear Information System (INIS)

    Rapado, Manuel; Paredes, Mayte; Altanes, Sonia; Barrera, Gisela; Otero, Isabel; Peniche, Carlos; Gonzalez, Maykel

    2006-01-01

    Chitosan is obtained by mean of partial deacetylation of chitin. Due to the diverse biological properties of this polymer it has valuable medical applications. Some of these applications require sterile materials. For this purpose irradiation techniques seem to have advantages since they do not require any additives, which could contaminate the final sterile product with toxic residuals. The aims of the present study were to determinate the bio burden for assessing the sterilization dose and to identify the influence of the absorbed dose of gamma radiation on the molar mass and chemical structure of chitosan. Changes in polymer features were evaluated by comparing the results obtained from the characterization of treated and raw polymers. The obtained results have been shown chain cleavage caused by irradiation. It was revealed by a decrease in the intrinsic viscosities of the polymers. The invariance of the infrared spectra of polymer indicates that chain degradation occurs without significant change of the chemical structure. The results obtained have practical implication in the field of radiation sterilization of chitosan used for biotechnology, medicine and pharmacy

  14. Control of molecular weight distribution in synthesis of poly(2-hydroxyethyl methacrylate) using ultrasonic irradiation.

    Science.gov (United States)

    Kubo, Masaki; Kondo, Takayuki; Matsui, Hideki; Shibasaki-Kitakawa, Naomi; Yonemoto, Toshikuni

    2018-01-01

    Poly(2-hydroxyethyl methacrylate) (PHEMA) was synthesized using ultrasonic irradiation without any chemical initiator. The effect of the ultrasonic power intensity on the time course of the conversion to polymer, the number average molecular weight, and the polydispersity were investigated in order to synthesize a polymer with a low molecular weight distribution (i.e., low polydispersity). The conversion to polymer increased with time. A higher ultrasonic power intensity resulted in a faster reaction rate. The number average molecular weight increased during the early stage of the reaction and then gradually decreased with time. A higher ultrasonic intensity resulted in a faster degradation rate of the polymer. The polydispersity decreased with time. This was because the degradation rate of a polymer with a higher molecular weight was faster than that of a polymer with a lower molecular weight. A polydispersity below 1.3 was obtained under ultrasonic irradiation. By changing the ultrasonic power intensity during the reaction, the number average molecular weight can be controlled while maintaining low polydispersity. When the ultrasonic irradiation was halted, the reactions stopped and the number average molecular weight and polydispersity did not change. On the basis of the experimental results, a kinetic model for synthesis of PHEMA under ultrasonic irradiation was constructed considering both polymerization and polymer degradation. The kinetic model was in good agreement with the experimental results for the time courses of the conversion to polymer, the number average molecular weight, and the polydispersity for various ultrasonic power intensities. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Acoustic detection of ultra-high energy cascades in ice

    Energy Technology Data Exchange (ETDEWEB)

    Boeser, S.

    2006-12-08

    Current underwater optical neutrino telescopes are designed to detect neutrinos from astrophysical sources with energies in the TeV range. Due to the low fluxes and small cross sections, no high energy neutrinos of extraterrestrial origin have been observed so far. Only the Cherenkov neutrino detectors on the km{sup 3} scale that are currently under construction will have the necessary volume to observe these rare interactions. For the guaranteed source of neutrinos from interactions of the ultra-high energy cosmic at EeV energies rays with the ambient cosmic microwave background, event rates of only one per year are expected in these experiments. To measure the flux and verify the predicted cross sections of these cosmogenic neutrinos, an observed volume of the order of 100 km{sup 3} will be necessary, that will not be feasible with existing detection techniques. Alternative methods are required to build a detector on these scales. One promising idea is to record the acoustic waves generated in hadronic or electromagnetic cascades following the neutrino interaction. The higher amplitudes of the sonic signal and the large expected absorption length of sound favour South Polar ice instead of sea water as a medium. The prerequisites for an estimate of the potential of such a detector are suitable acoustic sensors, a verification of the model of thermo-acoustic sound generation and a determination of the acoustic properties of the ice. In a theoretical derivation the mechanism of thermo-elastic excitation of acoustic waves was shown to be equivalent for isotropic solids and liquids. Following a detailed analysis of the existing knowledge a simulation study of a hybrid optical-radio-acoustic detector has been performed. Ultrasonic sensors dedicated to in-ice application were developed and have been used to record acoustic signals from intense proton and laser beams in water and ice. With the obtained experience, the hitherto largest array of acoustic sensors and

  16. Ultra-high-energy cosmic rays from radio galaxies

    Science.gov (United States)

    Eichmann, B.; Rachen, J. P.; Merten, L.; van Vliet, A.; Becker Tjus, J.

    2018-02-01

    Radio galaxies are intensively discussed as the sources of cosmic rays observed above about 3 × 1018 eV, called ultra-high energy cosmic rays (UHECRs). We present a first, systematic approach that takes the individual characteristics of these sources into account, as well as the impact of the extragalactic magnetic-field structures up to a distance of 120 Mpc. We use a mixed simulation setup, based on 3D simulations of UHECRs ejected by observed, individual radio galaxies taken out to a distance of 120 Mpc, and on 1D simulations over a continuous source distribution contributing from beyond 120 Mpc. Additionally, we include the ultra-luminous radio galaxy Cygnus A at a distance of about 250 Mpc, as its contribution is so strong that it must be considered as an individual point source. The implementation of the UHECR ejection in our simulation setup, both that of individual radio galaxies and the continuous source function, is based on a detailed consideration of the physics of radio jets and standard first-order Fermi acceleration. This allows to derive the spectrum of ejected UHECR as a function of radio luminosity, and at the same time provides an absolute normalization of the problem involving only a small set of parameters adjustable within narrow constraints. We show that the average contribution of radio galaxies taken over a very large volume cannot explain the observed features of UHECRs measured at Earth. However, we obtain excellent agreement with the spectrum, composition, and arrival-direction distribution of UHECRs measured by the Pierre Auger Observatory, if we assume that most UHECRs observed arise from only two sources: the ultra-luminous radio galaxy Cygnus A, providing a mostly light composition of nuclear species dominating up to about 6 × 1019 eV, and the nearest radio galaxy Centaurus A, providing a heavy composition dominating above 6 × 1019 eV . Here we have to assume that extragalactic magnetic fields out to 250 Mpc, which we did not

  17. Acoustic detection of ultra-high energy cascades in ice

    International Nuclear Information System (INIS)

    Boeser, S.

    2006-01-01

    Current underwater optical neutrino telescopes are designed to detect neutrinos from astrophysical sources with energies in the TeV range. Due to the low fluxes and small cross sections, no high energy neutrinos of extraterrestrial origin have been observed so far. Only the Cherenkov neutrino detectors on the km 3 scale that are currently under construction will have the necessary volume to observe these rare interactions. For the guaranteed source of neutrinos from interactions of the ultra-high energy cosmic at EeV energies rays with the ambient cosmic microwave background, event rates of only one per year are expected in these experiments. To measure the flux and verify the predicted cross sections of these cosmogenic neutrinos, an observed volume of the order of 100 km 3 will be necessary, that will not be feasible with existing detection techniques. Alternative methods are required to build a detector on these scales. One promising idea is to record the acoustic waves generated in hadronic or electromagnetic cascades following the neutrino interaction. The higher amplitudes of the sonic signal and the large expected absorption length of sound favour South Polar ice instead of sea water as a medium. The prerequisites for an estimate of the potential of such a detector are suitable acoustic sensors, a verification of the model of thermo-acoustic sound generation and a determination of the acoustic properties of the ice. In a theoretical derivation the mechanism of thermo-elastic excitation of acoustic waves was shown to be equivalent for isotropic solids and liquids. Following a detailed analysis of the existing knowledge a simulation study of a hybrid optical-radio-acoustic detector has been performed. Ultrasonic sensors dedicated to in-ice application were developed and have been used to record acoustic signals from intense proton and laser beams in water and ice. With the obtained experience, the hitherto largest array of acoustic sensors and transmitters was

  18. Correlation between electron-irradiation defects and applied stress in graphene: A molecular dynamics study

    Energy Technology Data Exchange (ETDEWEB)

    Kida, Shogo; Yamamoto, Masaya; Kawata, Hiroaki; Hirai, Yoshihiko; Yasuda, Masaaki, E-mail: yasuda@pe.osakafu-u.ac.jp [Department of Physics and Electronics, Osaka Prefecture University, Sakai, Osaka 599-8531 (Japan); Tada, Kazuhiro [Department of Electrical and Control Systems Engineering, National Institute of Technology, Toyama College, Toyama 939-8630 (Japan)

    2015-09-15

    Molecular dynamics (MD) simulations are performed to study the correlation between electron irradiation defects and applied stress in graphene. The electron irradiation effect is introduced by the binary collision model in the MD simulation. By applying a tensile stress to graphene, the number of adatom-vacancy (AV) and Stone–Wales (SW) defects increase under electron irradiation, while the number of single-vacancy defects is not noticeably affected by the applied stress. Both the activation and formation energies of an AV defect and the activation energy of an SW defect decrease when a tensile stress is applied to graphene. Applying tensile stress also relaxes the compression stress associated with SW defect formation. These effects induced by the applied stress cause the increase in AV and SW defect formation under electron irradiation.

  19. Immune-enhancing activities of low molecular weight β-glucan depolymerized by gamma irradiation

    Science.gov (United States)

    Sung, Nak-Yun; Byun, Eui-Hong; Kwon, Sun-Kyu; Song, Beom-Seok; Choi, Jong-il; Kim, Jae-Hun; Byun, Myung-Woo; Yoo, Young-Choon; Kim, Mee-Ree; Lee, Ju-Woon

    2009-07-01

    β-glucans are structural cell wall polymers of many microorganisms and cereals which possess immunomodulatory properties and have been used in the food, cosmetic and medical industry. In our previous study, β-glucan was depolymerized by gamma irradiation and leads to improve the solubility and viscosity. This study was carried out to evaluate the functional properties, mainly immune-enhancing activities of low molecular weight β-glucan fragmented by gamma irradiation. The results showed that RAW 264.7 macrophage cell stimulation activities of irradiated β-glucan were higher than that of non-irradiated β-glucan. In addition, the oral administration of gamma-irradiated β-glucan significantly increased the proliferation and cytokine (IFN-γ and IL-2) release of spleen and Peyer's patch cells compared with non-irradiated β-glucan. In conclusion, gamma irradiation could be used as an effective method for the production of depolymerized β-glucan improved functional property such as immunomodulatory activity.

  20. Immune-enhancing activities of low molecular weight β-glucan depolymerized by gamma irradiation

    International Nuclear Information System (INIS)

    Sung, Nak-Yun; Byun, Eui-Hong; Kwon, Sun-Kyu; Song, Beom-Seok; Choi, Jong-il; Kim, Jae-Hun; Byun, Myung-Woo; Yoo, Young-Choon; Kim, Mee-Ree; Lee, Ju-Woon

    2009-01-01

    β-glucans are structural cell wall polymers of many microorganisms and cereals which possess immunomodulatory properties and have been used in the food, cosmetic and medical industry. In our previous study, β-glucan was depolymerized by gamma irradiation and leads to improve the solubility and viscosity. This study was carried out to evaluate the functional properties, mainly immune-enhancing activities of low molecular weight β-glucan fragmented by gamma irradiation. The results showed that RAW 264.7 macrophage cell stimulation activities of irradiated β-glucan were higher than that of non-irradiated β-glucan. In addition, the oral administration of gamma-irradiated β-glucan significantly increased the proliferation and cytokine (IFN-γ and IL-2) release of spleen and Peyer's patch cells compared with non-irradiated β-glucan. In conclusion, gamma irradiation could be used as an effective method for the production of depolymerized β-glucan improved functional property such as immunomodulatory activity.

  1. Molecular dynamics study on interfacial thermal conductance of unirradiated and irradiated SiC/C

    International Nuclear Information System (INIS)

    Wang, Qingyu; Wang, Chenglong; Zhang, Yue; Li, Taosheng

    2014-01-01

    SiC f /SiC composite materials have been considered as candidate structural materials for several types of advanced nuclear reactors. Both experimental and computer simulations studies have revealed the degradation of thermal conductivity for this material after irradiation. The objective of this study is to investigate the effect of SiC/graphite interface structure and irradiation on the interfacial thermal conductance by using molecular dynamics simulation. Five SiC/graphite composite models were created with different interface structures, and irradiation was introduced near the interfaces. Thermal conductance was calculated by means of reverse-NEMD method. Results show that there is a positive correlation between the interfacial energy and interfacial C–Si bond quantity, and irradiated models showed higher interfacial energy compared with their unirradiated counterparts. Except the model with graphite atom plane parallel to the interface, the interfacial thermal conductance of unirradiated and irradiated (1000 eV) models, increases as the increase of interfacial energy, respectively. For all irradiated models, lattice defects are of importance in impacting the interfacial thermal conductance depending on the interface structure. For the model with graphite layer parallel to the interface, the interfacial thermal conductance increased after irradiation, for the other models the interfacial thermal conductance decreased. The vibrational density of states of atoms in the interfacial region was calculated to analyze the phonon mismatch at the interface

  2. Innovative Ultra-High Efficiency Cryogenic Actuators for Rocket Test Facilities, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The SBIR Phase I project will develop advanced ultra-high efficiency cryogenic actuators for NASA cryogenic fluid transfer application. The actuator will have low...

  3. Failure Modes of a Unidirectional Ultra-High-Modulus Carbon-Fiber/Carbon-Matrix Composite

    National Research Council Canada - National Science Library

    Zaldivar, R

    1998-01-01

    The objective of this study was to observe the effects of various microstructural features on the in situ, room-temperature tensile fracture behavior of an ultra-high-modulus, unidirectional carbon/carbon (C/C...

  4. Probing physics at extreme energies with cosmic ultra-high energy ...

    Indian Academy of Sciences (India)

    testing new particle physics. Keywords. Ultra-high ... conventional theories of CR origin based on acceleration of charged particles in powerful ... Before discussing specific scenarios for UHECR origin we give a short account of the numerical ...

  5. Ultra-high performance concrete : a state-of-the-art report for the bridge community.

    Science.gov (United States)

    2013-06-01

    "The term Ultra-High Performance Concrete (UHPC) refers to a relatively new class of advanced cementitious : composite materials whose mechanical and durability properties far surpass those of conventional concrete. This : class of concrete has been ...

  6. Design and evaluation of a single-span bridge using ultra-high performance concrete.

    Science.gov (United States)

    2009-09-01

    "Research presented herein describes an application of a newly developed material called Ultra-High Performance Concrete (UHPC) to a : single-span bridge. The two primary objectives of this research were to develop a shear design procedure for possib...

  7. Durability and smart condition assessment of ultra-high performance concrete in cold climates.

    Science.gov (United States)

    2016-12-31

    The goals of this study were to develop ecological ultra-high performance concrete (UHPC) with local materials and supplementary cementitious materials and to evaluate the long-term performance of UHPC in cold climates using effective mechanical test...

  8. The Time Lens Concept Applied to Ultra-High-Speed OTDM Signal Processing

    DEFF Research Database (Denmark)

    Clausen, Anders; Palushani, Evarist; Mulvad, Hans Christian Hansen

    2013-01-01

    This survey paper presents some of the applications where the versatile time-lens concept successfully can be applied to ultra-high-speed serial systems by offering expected needed functionalities for future optical communication networks.......This survey paper presents some of the applications where the versatile time-lens concept successfully can be applied to ultra-high-speed serial systems by offering expected needed functionalities for future optical communication networks....

  9. SimProp: a simulation code for ultra high energy cosmic ray propagation

    International Nuclear Information System (INIS)

    Aloisio, R.; Grillo, A.F.; Boncioli, D.; Petrera, S.; Salamida, F.

    2012-01-01

    A new Monte Carlo simulation code for the propagation of Ultra High Energy Cosmic Rays is presented. The results of this simulation scheme are tested by comparison with results of another Monte Carlo computation as well as with the results obtained by directly solving the kinetic equation for the propagation of Ultra High Energy Cosmic Rays. A short comparison with the latest flux published by the Pierre Auger collaboration is also presented

  10. Laser beam welding of new ultra-high strength and supra-ductile steels

    OpenAIRE

    Dahmen, M.

    2015-01-01

    Ultra-high strength and supra-ductile are entering fields of new applications. Those materials are excellent candidates for modern light-weight construction and functional integration. As ultra-high strength steels the stainless martensitic grade 1.4034 and the bainitic steel UNS 53835 are investigated. For the supra-ductile steels stand two high austenitic steels with 18 and 28 % manganese. As there are no processing windows an approach from the metallurgical base on is required. Adjusting t...

  11. Connections in Precast Buildings using Ultra High-Strength Fibre Reinforced Concrete

    DEFF Research Database (Denmark)

    Hansen, Lars Pilegaard

    1995-01-01

    Ultra high-strength concrete adds new dimensions to the design of concrete structures. It is a brittle material but introducing fibres into the matrix changes the material into a highly ductile material. Furthermore, the fibre reinforcement increases the anchorage of traditional reinforcement bar...... and the fire resistance. Such a fibre reinforced ultra high-strength material has been used to develop a simple joint solution between slab elements in a column - slab building system....

  12. Ultra-high performance size-exclusion chromatography in polar solvents.

    Science.gov (United States)

    Vancoillie, Gertjan; Vergaelen, Maarten; Hoogenboom, Richard

    2016-12-23

    Size-exclusion chromatography (SEC) is amongst the most widely used polymer characterization methods in both academic and industrial polymer research allowing the determination of molecular weight and distribution parameters, i.e. the dispersity (Ɖ), of unknown polymers. The many advantages, including accuracy, reproducibility and low sample consumption, have contributed to the worldwide success of this analytical technique. The current generation of SEC systems have a stationary phase mostly containing highly porous, styrene-divinylbenzene particles allowing for a size-based separation of various polymers in solution but limiting the flow rate and solvent compatibility. Recently, sub-2μm ethylene-bridged hybrid (BEH) packing materials have become available for SEC analysis. These packing materials can not only withstand much higher pressures up to 15000psi but also show high spatial stability towards different solvents. Combining these BEH columns with the ultra-high performance LC (UHPLC) technology opens up UHP-SEC analysis, showing strongly reduced runtimes and unprecedented solvent compatibility. In this work, this novel characterization technique was compared to conventional SEC using both highly viscous and highly polar solvents as eluent, namely N,N-dimethylacetamide (DMAc), N,N-dimethylformamide (DMF) and methanol, focusing on the suitability of the BEH-columns for analysis of highly functional polymers. The results show a high functional group compatibility comparable with conventional SEC with remarkably short runtimes and enhanced resolution in methanol. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. Novel PVA-DNA nanoparticles prepared by ultra high pressure technology for gene delivery

    International Nuclear Information System (INIS)

    Kimura, Tsuyoshi; Okuno, Akira; Miyazaki, Kozo; Furuzono, Tsutomu; Ohya, Yuichi; Ouchi, Tatsuro; Mutsuo, Shingo; Yoshizawa, Hidekazu; Kitamura, Yoshiro; Fujisato, Toshiyta; Kishida, Akio

    2004-01-01

    Polyvinyl alcohol (PVA)-DNA nanoparticles have been developed by ultra high pressure (UHP) technology. Mixture solutions of DNA and PVA having various molecular weights (Mw) and degree of saponifications (DS) were treated under 10,000 atmospheres (981 MPa) condition at 40 deg. C for 10 min. Agarose gel electrophoresis and scanning electron microscope observation revealed that the PVA-DNA nanoparticles with average diameter of about 200 nm were formed. Using PVA of higher Mw and degree of saponifications, the amount of nanoparticles formed increased. The driving force of nanoparticle formation was the hydrogen bonding between DNA and PVA. In order to apply the PVA-DNA nanoparticles for gene delivery, the cytotoxicity and the cellular uptake of them were investigated using Raw264 cell lines. The cell viability was not influenced whether the presence of the PVA-DNA nanoparticles. Further, the nanoparticles internalized into cells were observed by fluorescent microscope. These results indicates that the PVA-DNA nanoparticles prepared by UHP technology showed be useful as drug carrier, especially for gene delivery

  14. Ultra-high performance liquid chromatography tandem high-resolution mass spectrometry study of tricyclazole photodegradation products in water.

    Science.gov (United States)

    Gosetti, Fabio; Chiuminatto, Ugo; Mazzucco, Eleonora; Mastroianni, Rita; Bolfi, Bianca; Marengo, Emilio

    2015-06-01

    This paper reports the study of the photodegradation reactions that tricyclazole can naturally undergo, under the action of sunlight, in aqueous solutions of standard tricyclazole and of the commercial BEAM(TM) formulation. The analyses are carried out by ultra-high performance liquid chromatography technique coupled with high-resolution tandem mass spectrometry. Analysis of both tricyclazole and BEAM(TM) water solutions undergone to hydrolysis does not evidence new chromatographic peaks with respect to the not treated solutions. On the contrary, analysis of the same samples subjected to sunlight irradiation shows a decreased intensity of tricyclazole signal and the presence of new chromatographic peaks. Two photodegradation products of tricyclazole have been identified, one of which has been also quantified, being the commercial standard available. The pattern is similar for the solutions of the standard fungicide and of the BEAM(TM) formulation. The results obtained from eco-toxicological tests show that toxicity of tricyclazole standard solutions is greater than that of the irradiated ones, whereas toxicity levels of all the BEAM(TM) solutions investigated (non-irradiated, irradiated, and hydrolyzed) are comparable and lower than those shown by tricyclazole standard solutions. Experiments performed in paddy water solution show that there is no difference in the degradation products formed.

  15. Effect of gamma irradiation on the friction and wear of ultrahigh molecular weight polyethylene

    Science.gov (United States)

    Jones, W. R.; Hady, W. F.; Crugnola, A.

    1981-01-01

    The effect of sterilization gamma irradiation on the friction and wear properties of ultrahigh molecular weight polyethylene (UHMWPE) sliding against stainless steel 316L in dry air at 23 C is investigated, the results to be used in the development of artificial joints which are to surgically replace diseased human joints. A pin-on-disk sliding friction apparatus is used, a constant sliding speed in the range 0.061-0.27 m/s is maintained, a normal load of 1 kgf is applied with dead weight, and the irradiation dose levels are: 0, 2.5, and 5.0 Mrad. Wear and friction data and conditions for each of the ten tests are summarized, and include: (1) wear volume as a function of the sliding distance for the irradiation levels, (2) incremental wear rate, and (3) coefficient of friction as a function of the sliding distance. It is shown that (1) the friction and wear properties of UHMWPE are not significantly changed by the irradiation doses of 2.5 and 5.0 Mrad, (2) the irradiation increases the amount of insoluble gel as well as the amount of low molecular weight material, and (3) after run-in the wear rate is either steady or gradually decreases as a function of the sliding distance.

  16. Effects of γ-Irradiation on the Molecular Structures and Functions of Human Serum Albumin.

    Science.gov (United States)

    Hu, Xinxin; Song, Wei; Li, Wei; Guo, Changying; Yu, Zehua; Liu, Rutao

    2016-11-01

    In this paper, we use spectroscopic methods (fluorescence spectroscopy, UV absorption spectroscopy, and circular dichroism (CD) spectroscopy) to elucidate the effects of reactive oxygen species generated by γ-irradiation on the molecular properties of human serum albumin (HSA). The results of fluorescence spectroscopy indicated that oxidation by γ-irradiation can lead to conformational changes of HSA. Data of CD spectra suggested that with the increase of radiation dose the percentage of α-helix in HSA has decreased. The determination of protein hydrophobicity showed that the effective hydrophobicity of HSA decreased up to 62% compared to the native HSA solution due to the exposure to the γ-irradiation. Furthermore, small changes in the esterase-like activity of HSA were introduced because of oxidation. The content of bityrosine increased markedly, suggesting that the oxidized HSA was aggregated. Moreover, there was no obvious change in the molecular properties of HSA with low γ-irradiation dose. Changes happened when the irradiation dose exceeded 200 Gy. © 2016 Wiley Periodicals, Inc.

  17. Influence of the molecular modifications on the properties of EPDM elastomers under irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Davenas, J. E-mail: joel.davenas@univ-lyon1.fr; Stevenson, I.; Celette, N.; Vigier, G.; David, L

    2003-08-01

    The degradation of the mechanical behaviour of EPDM elastomers used as cable insulation materials has been investigated by mechanical spectroscopy and tensile tests for different formulations: unvulcanised EPDM, vulcanised and stabilised elastomer with an antioxidant. In all cases, {gamma}-irradiation of EPDM under oxygen leads to a reduction of the molecular mobility indicated by the shift of the glass transition relaxation temperature towards higher temperatures. Moreover, the molecular flow occurring above T{sub g} is suppressed after irradiation for the unvulcanised EPDM providing evidence of cross-linking. The competition between cross-linking and chain scissions is shown by the decrease of the storage modulus above the crystallites melting temperature ({approx}40 deg. C) at doses larger than 100 kGy. A strong increase of the Young modulus and reduction of the elongation at break of the non-vulcanised EPDM becoming more brittle are shown by stress/strain characterisations performed at 80 deg. C. At the opposite vulcanised EPDM exhibits higher elongation at break after crystallites melting. This evolution is interpreted by the competition between cross-linking and chain scissions, being hindered by the crystallites at room temperature. The intrinsic irradiation effects can be isolated after crystallite melting. The reduction of the molecular mobility can be explained by a chemi-crystallisation process assisted by chain scissions, leading to a more rigid phase upon irradiation.

  18. Influence of the molecular modifications on the properties of EPDM elastomers under irradiation

    International Nuclear Information System (INIS)

    Davenas, J.; Stevenson, I.; Celette, N.; Vigier, G.; David, L.

    2003-01-01

    The degradation of the mechanical behaviour of EPDM elastomers used as cable insulation materials has been investigated by mechanical spectroscopy and tensile tests for different formulations: unvulcanised EPDM, vulcanised and stabilised elastomer with an antioxidant. In all cases, γ-irradiation of EPDM under oxygen leads to a reduction of the molecular mobility indicated by the shift of the glass transition relaxation temperature towards higher temperatures. Moreover, the molecular flow occurring above T g is suppressed after irradiation for the unvulcanised EPDM providing evidence of cross-linking. The competition between cross-linking and chain scissions is shown by the decrease of the storage modulus above the crystallites melting temperature (∼40 deg. C) at doses larger than 100 kGy. A strong increase of the Young modulus and reduction of the elongation at break of the non-vulcanised EPDM becoming more brittle are shown by stress/strain characterisations performed at 80 deg. C. At the opposite vulcanised EPDM exhibits higher elongation at break after crystallites melting. This evolution is interpreted by the competition between cross-linking and chain scissions, being hindered by the crystallites at room temperature. The intrinsic irradiation effects can be isolated after crystallite melting. The reduction of the molecular mobility can be explained by a chemi-crystallisation process assisted by chain scissions, leading to a more rigid phase upon irradiation

  19. Design Strategies for Ultra-high Efficiency Photovoltaics

    Science.gov (United States)

    Warmann, Emily Cathryn

    While concentrator photovoltaic cells have shown significant improvements in efficiency in the past ten years, once these cells are integrated into concentrating optics, connected to a power conditioning system and deployed in the field, the overall module efficiency drops to only 34 to 36%. This efficiency is impressive compared to conventional flat plate modules, but it is far short of the theoretical limits for solar energy conversion. Designing a system capable of achieving ultra high efficiency of 50% or greater cannot be achieved by refinement and iteration of current design approaches. This thesis takes a systems approach to designing a photovoltaic system capable of 50% efficient performance using conventional diode-based solar cells. The effort began with an exploration of the limiting efficiency of spectrum splitting ensembles with 2 to 20 sub cells in different electrical configurations. Incorporating realistic non-ideal performance with the computationally simple detailed balance approach resulted in practical limits that are useful to identify specific cell performance requirements. This effort quantified the relative benefit of additional cells and concentration for system efficiency, which will help in designing practical optical systems. Efforts to improve the quality of the solar cells themselves focused on the development of tunable lattice constant epitaxial templates. Initially intended to enable lattice matched multijunction solar cells, these templates would enable increased flexibility in band gap selection for spectrum splitting ensembles and enhanced radiative quality relative to metamorphic growth. The III-V material family is commonly used for multijunction solar cells both for its high radiative quality and for the ease of integrating multiple band gaps into one monolithic growth. The band gap flexibility is limited by the lattice constant of available growth templates. The virtual substrate consists of a thin III-V film with the desired

  20. Atomistic simulation of damage production by atomic and molecular ion irradiation in GaN

    International Nuclear Information System (INIS)

    Ullah, M. W.; Kuronen, A.; Nordlund, K.; Djurabekova, F.; Karaseov, P. A.; Titov, A. I.

    2012-01-01

    We have studied defect production during single atomic and molecular ion irradiation having an energy of 50 eV/amu in GaN by molecular dynamics simulations. Enhanced defect recombination is found in GaN, in accordance with experimental data. Instantaneous damage shows non-linearity with different molecular projectile and increasing molecular mass. Number of instantaneous defects produced by the PF 4 molecule close to target surface is four times higher than that for PF 2 molecule and three times higher than that calculated as a sum of the damage produced by one P and four F ion irradiation (P+4×F). We explain this non-linearity by energy spike due to molecular effects. On the contrary, final damage created by PF 4 and PF 2 shows a linear pattern when the sample cools down. Total numbers of defects produced by Ag and PF 4 having similar atomic masses are comparable. However, defect-depth distributions produced by these species are quite different, also indicating molecular effect.

  1. Interaction of ultra-high intensity laser pulse with a mass limited targets

    International Nuclear Information System (INIS)

    Andreev, A.A.; Platonov, K.Yu.; Limpouch, J.; Psikal, J.; Kawata, S.

    2006-01-01

    Complete test of publication follows. Ultra-high intensity laser pulses may be produced now via CPA scheme by using very short laser pulses of a relatively low energy. Interaction of such pulses with massive target is not very efficient as the energy delivered to charged particles spreads out quickly over large distances and it is redistributed between many secondary particles. One possibility to limit this undesirable energy spread is to use mass limited targets (MLT), for example droplets, big clusters or small foil sections. This is an intermediate regime in target dimensions between bulk solid and nanometer-size atomic cluster targets. A few experimental and theoretical studies have been carried out on laser absorption, fast particle generation and induced nuclear fusion reactions in the interaction of ultrashort laser pulses with MLT plasma. We investigate here laser interactions with MLT via 2D3V relativistic electromagnetic PIC simulations. We assume spherical droplet as a typical MLT. However, the sphere is represented in 2D simulations by an infinite cylinder irradiated uniformly along its length. We assume that MLT is fully ionized before main pulse interaction either due to insufficient laser contrast or due to a prepulse. For simplicity, we assume homogeneous plasma of high initial temperature. We analyze the interaction of relativistic laser pulses of various polarizations with targets of different shapes, such as a foil, quadrant and sphere. The mechanisms of laser absorption, electron and ion acceleration are clarified for different laser and target parameters. When laser interacts with the target front side, kinetic energy of electrons rises rapidly with fast oscillations in the kinetic and field energy, caused by electron oscillations in the laser field. Small energy oscillations, observed later, are caused by the electron motion back and forth through the droplet. Approximately 40% of laser energy is transferred to the kinetic energy of electrons

  2. Deformation and degradation of polymers in ultra-high-pressure liquid chromatography.

    Science.gov (United States)

    Uliyanchenko, Elena; van der Wal, Sjoerd; Schoenmakers, Peter J

    2011-09-28

    Ultra-high-pressure liquid chromatography (UHPLC) using columns packed with sub-2 μm particles has great potential for separations of many types of complex samples, including polymers. However, the application of UHPLC for the analysis of polymers meets some fundamental obstacles. Small particles and narrow bore tubing in combination with high pressures generate significant shear and extensional forces in UHPLC systems, which may affect polymer chains. At high stress conditions flexible macromolecules may become extended and eventually the chemical bonds in the molecules can break. Deformation and degradation of macromolecules will affect the peak retention and the peak shape in the chromatogram, which may cause errors in the obtained results (e.g. the calculated molecular-weight distributions). In the present work we explored the limitations of UHPLC for the analysis of polymers. Degradation and deformation of macromolecules were studied by collecting and re-injecting polymer peaks and by off-line two-dimensional liquid chromatography. Polystyrene standards with molecular weight of 4 MDa and larger were found to degrade at UHPLC conditions. However, for most polymers degradation could be avoided by using low linear velocities. No degradation of 3-MDa PS (and smaller) was observed at linear velocities up to 7 mm/s. The column frits were implicated as the main sources of polymer degradation. The extent of degradation was found to depend on the type of the column and on the column history. At high flow rates degradation was observed without a column being installed. We demonstrated that polymer deformation preceded degradation. Stretched polymers eluted from the column in slalom chromatography mode (elution order opposite to that in SEC or HDC). Under certain conditions we observed co-elution of large and small PS molecules though a convolution of slalom chromatography and hydrodynamic chromatography. Copyright © 2011 Elsevier B.V. All rights reserved.

  3. Molecular dynamics simulations of the structure evolutions of Cu-Zr metallic glasses under irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Lang, Lin [College of Materials Science and Engineering, Hunan University, Changsha 410082 (China); Department of Applied Physics, School of Physics and Electronics, Hunan University, Changsha 410082 (China); Tian, Zean; Xiao, Shifang [Department of Applied Physics, School of Physics and Electronics, Hunan University, Changsha 410082 (China); Deng, Huiqiu, E-mail: hqdeng@hnu.edu.cn [Department of Applied Physics, School of Physics and Electronics, Hunan University, Changsha 410082 (China); Ao, Bingyun [Science and Technology on Surface Physics and Chemistry Laboratory, Mianyang 621907 (China); Chen, Piheng, E-mail: chenpiheng@caep.cn [Science and Technology on Surface Physics and Chemistry Laboratory, Mianyang 621907 (China); Hu, Wangyu [College of Materials Science and Engineering, Hunan University, Changsha 410082 (China)

    2017-02-15

    Highlights: • The structural evolution of Cu{sub 64.5}Zr{sub 35.5} MG under irradiation was studied. • The structure clusters were analyzed using the LSCA method. • Most of these radiation damages have been self-recovered quickly. - Abstract: Molecular dynamics simulations have been performed to investigate the structural evolution of Cu{sub 64.5}Zr{sub 35.5} metallic glasses under irradiation. The largest standard cluster analysis (LSCA) method was used to quantify the microstructure within the collision cascade regions. It is found that the majority of clusters within the collision cascade regions are full and defective icosahedrons. Not only the smaller structures (common neighbor subcluster) but also primary clusters greatly changed during the collision cascades; while most of these radiation damages self-recover quickly in the following quench states. These findings indicate the Cu-Zr metallic glasses have excellent irradiation-resistance properties.

  4. Imaging Frontostriatal Function in Ultra-High-Risk, Early, and Chronic Schizophrenia During Executive Processing

    Science.gov (United States)

    Morey, Rajendra A.; Inan, Seniha; Mitchell, Teresa V.; Perkins, Diana O.; Lieberman, Jeffrey A.; Belger, Aysenil

    2009-01-01

    Context Individuals experiencing prodromal symptoms of schizophrenia (ultra-high-risk group) demonstrate impaired performance on tasks of executive function, attention, and working memory. The neurobiological underpinnings of such executive deficits in ultra-high-risk individuals remains unclear. Objective We assessed frontal and striatal functions during a visual oddball continuous performance task, in ultra-high-risk, early, and chronic schizophrenic patients with the use of functional magnetic resonance imaging. Design Cross-sectional case-control design. Setting Community; outpatient clinic. Patients Fifty-two individuals (control, n = 16; ultra-high risk, n = 10; early, n = 15; chronic, n = 11) from a referred clinical sample and age- and sex-matched control volunteers underwent scanning. Main Outcome Measures Percentage of active voxels and percentage signal change calculated for the anterior cingulate gyrus (ACG), middle frontal gyrus (MFG), inferior frontal gyrus (IFG), basal ganglia, and thalamus. Performance on the visual oddball task was measured with percentage of hits and d′ (a measure based on the hit rate and the false-alarm rate). Results The ultra-high-risk group showed significantly smaller differential activation between task-relevant and task-irrelevant stimuli in the frontal regions (ACG, IFG, MFG) than the control group. Frontostriatal activation associated with target stimuli in the early and chronic groups was significantly lower than the control group, while the ultra-high-risk group showed a trend toward the early group. Conclusions Our findings suggest that prefrontal function begins to decline before the onset of syndromally defined illness and hence may represent a vulnerability marker in assessing the risk of developing psychotic disorders among ultra-high-risk individuals. PMID:15753238

  5. Effect of molecular weight reduction by gamma irradiation on chitosan film properties

    Energy Technology Data Exchange (ETDEWEB)

    García, Mario A., E-mail: marioifal@gmail.com [Pharmacy and Food Institute, University of Havana, St. 222 No. 2317, ZC 13600 Havana (Cuba); Pérez, Liliam [Pharmacy and Food Institute, University of Havana, St. 222 No. 2317, ZC 13600 Havana (Cuba); Paz, Nilia de la [Drugs Research and Development Center, Ave. 26 No. 1605, Havana (Cuba); González, Juan [Food Industry Research Institute, Carretera al Guatao km 3 1/2, Havana, CP 19200 (Cuba); Rapado, Manuel [Radiobiology Department, Center for Technological Applications and Nuclear Development, St. 30 No. 502, Playa, Havana (Cuba); Casariego, Alicia [Pharmacy and Food Institute, University of Havana, St. 222 No. 2317, ZC 13600 Havana (Cuba)

    2015-10-01

    The present work aimed the influence of molecular weight (MW) reduction by irradiation with {sup 60}Co and polymer concentration on some physical properties of chitosan films. Irradiation of chitosan with a MW of 275.221 kDa and 74.74% of deacetylation degree was performed using a {sup 60}Co source to provide doses of 5, 10, 20 and 50 kGy to obtain chitosans with molecular weights of 247.847, 221.563, 126.469 and 77.063 kDa, respectively. Films were prepared via the solution casting method. Film-forming solutions (FFS) of chitosan irradiated or not, were prepared at 1.5 and 2% (w/v) in a solution of lactic acid at 1% (v/v) and 0.1% (v/v) of Tween 80. The FFS were poured into glass plates of 400 cm{sup 2} and dried at 60 °C during 10 h without airflow. The decrease of MW and increase of chitosan concentration increased the tensil strength and water vapor permeability while decreased the elongation at break of the films. The chitosan MW did not significantly influence (p > 0.05) the water solubility of films within a same polymer concentration. There was a decrease in the films' brightness with the increase of concentration and a decrease of the MW of irradiated chitosan, while the b* values of films increased and there was an increasing tendency of their apparent opacity. - Highlights: • MW reduction by {sup 60}Co irradiation increased the tensil strength of chitosan films. • MW reduction increased the water vapor permeability of chitosan films. • MW did not affect the films' water solubility within a same chitosan concentration. • Films' brightness decreased with the chitosan molecular weight reduction.

  6. Effect of molecular weight reduction by gamma irradiation on chitosan film properties

    International Nuclear Information System (INIS)

    García, Mario A.; Pérez, Liliam; Paz, Nilia de la; González, Juan; Rapado, Manuel; Casariego, Alicia

    2015-01-01

    The present work aimed the influence of molecular weight (MW) reduction by irradiation with 60 Co and polymer concentration on some physical properties of chitosan films. Irradiation of chitosan with a MW of 275.221 kDa and 74.74% of deacetylation degree was performed using a 60 Co source to provide doses of 5, 10, 20 and 50 kGy to obtain chitosans with molecular weights of 247.847, 221.563, 126.469 and 77.063 kDa, respectively. Films were prepared via the solution casting method. Film-forming solutions (FFS) of chitosan irradiated or not, were prepared at 1.5 and 2% (w/v) in a solution of lactic acid at 1% (v/v) and 0.1% (v/v) of Tween 80. The FFS were poured into glass plates of 400 cm 2 and dried at 60 °C during 10 h without airflow. The decrease of MW and increase of chitosan concentration increased the tensil strength and water vapor permeability while decreased the elongation at break of the films. The chitosan MW did not significantly influence (p > 0.05) the water solubility of films within a same polymer concentration. There was a decrease in the films' brightness with the increase of concentration and a decrease of the MW of irradiated chitosan, while the b* values of films increased and there was an increasing tendency of their apparent opacity. - Highlights: • MW reduction by 60 Co irradiation increased the tensil strength of chitosan films. • MW reduction increased the water vapor permeability of chitosan films. • MW did not affect the films' water solubility within a same chitosan concentration. • Films' brightness decreased with the chitosan molecular weight reduction

  7. Self-irradiation damage in 4H-SiC by molecular dynamics simulation

    International Nuclear Information System (INIS)

    Han Miaomiao; Wang Qingyu; Li Taosheng; Li Zhongyu

    2014-01-01

    The development of nuclear technology is closely and inseparably related to the improvements of materials irradiation performance. The irradiation damage of nuclear materials is an important issue of characteristics and difficulties. Because of the excellent features, SiC becomes one of the candidate materials for the cladding material and structure material in fast neutron reactor and fusion reactor. As one of the polytypes, 4H-SiC has prospective important applications in a strong irradiation environment. In this work, molecular dynamics (MD) simulation was performed to study the irradiation-induced cascade damage in single-crystalline 4H-SiC to get the microscopic evolution during the irradiation, in the aim of getting access to the detail that we cannot get from experiments. The software LAMMPS was used to simulate the damage formation process and the recovery process. The results showed that the initial project direction, the temperature and PKA energy exerted significant effects on the number and morphology of defects. (authors)

  8. Phenotype and molecular analysis of M1 generation of stylosanthes irradiated by 60Co

    International Nuclear Information System (INIS)

    Zhang Weili; Liu Fengmin

    2012-01-01

    The seeds of Stylosanthes guianensis SW. ‘Reyan No.13’ were irradiated by 60 Co at 0, 325, 487 and 974 Gy. Phenotype and molecular variations of Stylosanthes M 1 generations were studied. Germination percentage, plant height, leaf length and stem diameter of M 1 seedlings were determined using SRAP-PCR. Results showed that biological character indices of treatments were significantly lower than that of control (CK). Irradiation inhibited plant growth. Growth indices of 974 Gy treatment, except leaf length, were significantly lower than CK and other two treatments. Eight effective primers selected from 24 primers combination were used for SRAP-PCR. SRAP analysis revealed that the 57 of 88 DNA fragments were amplified showing polymorphisms. The average percentage of polymorphic bands was 64.77%. The effects of 60 Coγ irradiation on DNA variation of seedlings were varied from different treatments. Numbers of polymorphic bands changed after irradiation. Coefficient of variation was in direct proportion to irradiation doses. Variation rates of 325 Gy, 487 Gy and 974 Gy treatments were 22.0%, 38.1% and 41.5%, respectively. The Nei’s genetic similarity coefficient of all treatments was ranged from 0.585 to 0.780 by software NTSYSpc 2.1 based on SRAP results and the average Nei's coefficient was 0.678. The Nei’s genetic similarity coefficient of 974 Gy treatment was 0.585 and variation degree was highest among all treatments, 487 Gy treatment was second and 325 Gy treatment was the lowest one. Based on present bands, four irradiated treatments were classified into two major groups by UPGMA cluster analysis. Group 1 included CK, 325 Gy and 487 Gy treatment and group 2 included 974 Gy. SRAP analysis determined variation of Stylosanthes after irradiation and the results of SRAP analysis were consistent with their biological indexes in some extent

  9. Ultra-High-Contrast Laser Acceleration of Relativistic Electrons in Solid Targets

    Science.gov (United States)

    Higginson, Drew Pitney

    The cone-guided fast ignition approach to Inertial Confinement Fusion requires laser-accelerated relativistic electrons to deposit kilojoules of energy within an imploded fuel core to initiate fusion burn. One obstacle to coupling electron energy into the core is the ablation of material, known as preplasma, by laser energy proceeding nanoseconds prior to the main pulse. This causes the laser-absorption surface to be pushed back hundreds of microns from the initial target surface; thus increasing the distance that electrons must travel to reach the imploded core. Previous experiments have shown an order of magnitude decrease in coupling into surrogate targets when intentionally increasing the amount of preplasma. Additionally, for electrons to deposit energy within the core, they should have kinetic energies on the order of a few MeV, as less energetic electrons will be stopped prior to the core and more energetic electrons will pass through the core without depositing much energy. Thus a quantitative understanding of the electron energy spectrum and how it responds to varied laser parameters is paramount for fast ignition. For the first time, this dissertation quantitatively investigates the acceleration of electrons using an ultra-high-contrast laser. Ultra-high-contrast lasers reduce the laser energy that reaches the target prior to the main pulse; drastically reducing the amount of preplasma. Experiments were performed in a cone-wire geometry relevant to fast ignition. These experiments irradiated the inner-tip of a Au cone with the laser and observed electrons that passed through a Cu wire attached to the outer-tip of the cone. The total emission of Kalpha x-rays is used as a diagnostic to infer the electron energy coupled into the wire. Imaging the x-ray emission allowed an effective path-length of electrons within the wire to be determined, which constrained the electron energy spectrum. Experiments were carried out on the ultra-high-contrast Trident laser

  10. Fast and sensitive analysis of beta blockers by ultra-high-performance liquid chromatography coupled with ultra-high-resolution TOF mass spectrometry.

    Science.gov (United States)

    Tomková, Jana; Ondra, Peter; Kocianová, Eva; Václavík, Jan

    2017-07-01

    This paper presents a method for the determination of acebutolol, betaxolol, bisoprolol, metoprolol, nebivolol and sotalol in human serum by liquid-liquid extraction and ultra-high-performance liquid chromatography coupled with ultra-high-resolution TOF mass spectrometry. After liquid-liquid extraction, beta blockers were separated on a reverse-phase analytical column (Acclaim RS 120; 100 × 2.1 mm, 2.2 μm). The total run time was 6 min for each sample. Linearity, limit of detection, limit of quantification, matrix effects, specificity, precision, accuracy, recovery and sample stability were evaluated. The method was successfully applied to the therapeutic drug monitoring of 108 patients with hypertension. This method was also used for determination of beta blockers in 33 intoxicated patients. Copyright © 2016 John Wiley & Sons, Ltd.

  11. Preparation, Characterization, and UV Irradiation of Mars Soil Analogues Under Simulated Martian Conditions to Support Detection of Molecular Biomarkers

    Science.gov (United States)

    Fornaro, T.; Brucato, J. R.; ten Kate, I. L.; Siljeström, S.; Steele, A.; Cody, G. D.; Hazen, R. M.

    2018-04-01

    We present laboratory activities of preparation, characterization, and UV irradiation processing of Mars soil analogues, which are key to support both in situ exploration and sample return missions devoted to detection of molecular biomarkers on Mars.

  12. Enantioseparation of dansyl amino acids by ultra-high pressure liquid chromatography using cationic β-cyclodextrins as chiral additives.

    Science.gov (United States)

    Xiao, Yin; Tan, Timothy Thatt Yang; Ng, Siu-Choon

    2011-04-07

    This work reports the application of ultra-high pressure liquid chromatography (UHPLC) for reasonably fast enantiorecognition of some dansyl amino acids by employing three cationic β-cyclodextrins (β-CDs) as chiral additives. Good resolutions were obtained on an Agilent C18 column (2.1 mm i.d.; 1.8 μm; 50 mm length) with 1% (v/v) triethylammonium acetate buffered at pH 4.7 and acetonitrile as the mobile phase. Most of the analytes could be baseline resolved within 10 min. Increased cationic CD concentration or acetonitrile proportion in the mobile phase results in a decreased retention factor but accentuated selectivity. Furthermore, molecular mechanics calculation was performed and found to be consistent with the experimental results. © The Royal Society of Chemistry 2011

  13. Design and performance of a soft-x-ray interferometer for ultra-high-resolution fourier transform spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Moler, E.J.; Hussain, Z.; Duarte, R.M.; Howells, M.R. [Lawrence Berkeley National Lab., CA (United States)

    1997-04-01

    A Fourier Transform Soft X-ray spectrometer (FT-SX) has been designed and is under construction for the Advanced Light Source (ALS) at Lawrence Berkeley National Laboratory as a branch of beamline 9.3.2. The spectrometer is a novel soft x-ray interferometer designed for ultra-high resolution (theoretical resolving power E/{delta}E{approximately}10{sup 6}) spectroscopy in the photon energy region of 60-120 eV. This instrument is expected to provide experimental results which sensitively test models of correlated electron processes in atomic and molecular physics. The design criteria and consequent technical challenges posed by the short wavelengths of x-rays and desired resolving power are discussed. The fundamental and practical aspects of soft x-ray interferometry are also explored.

  14. Molecular motions of non-crystalline poly(aryl ether-ether-ketone) PEEK and influence of electron beam irradiation

    International Nuclear Information System (INIS)

    Sasuga, T.; Hagiwara, M.

    1985-01-01

    The dynamic mechanical relaxation of non-crystalline poly(aryl ether-ether-ketone) PEEK and the one irradiated with electron beam were studied. The three distinct γ, β, α' relaxation maxima were observed in unirradiated PEEK from low to high temperature. It was revealed from the study on the irradiation effects that three different molecular processes are overlapped in γ relaxation peak, i.e., molecular motion of water bound to main chain, local motion of main chain, and local mode of the aligned and/or oriented moiety. The β relaxation connected with the glass transition occurred at 150 deg C and it shifted to higher temperature by irradiation. The α' relaxation which can be attributed to rearrangement of molecular chain due to crystallization was observed in unirradiated PEEK approx. 180 deg C and its magnitude decreased with the increase in irradiation dose. This effect indicates the formation of structures inhibiting crystallization such as crosslinking and/or short branching during irradiation. A new relaxation, β', appeared in the temperature range of 40 deg to 100 deg C by irradiation and its magnitude increased with dose. This relaxation was attributed to rearrangement of molecular chain from loosened packing around chain ends, which were introduced into the non-crystalline region by chain scission under irradiation, to more rigid molecular packing. (author)

  15. Continuous far red irradiation controls molecular properties of delta-aminolevulinate dehydratase in Raphanus Sativus seedlings

    Energy Technology Data Exchange (ETDEWEB)

    Balange, A.P. (Centre National de la Recherche Scientifique, 76-Mont Saint Aignan (France). Lab. de Photobiologie); Lambert, C. (U.E.R. Scientifique de Luminy, Dept. de Biologie Moleculaire et Cellulaire, Marseilles (France))

    1983-12-01

    8-Aminolevulinate dehydratase (EC 4.2.1.24) (ALAD) is a phytochrome-dependent enzyme. Under continuous far red light (FR), the intracellular location of ALAD is modified: in young irradiated seedling cotyledons (48 h from sowing) it is localised in the cytoplasm, as for seedlings kept in continuous darkness or irradiated but treated with erythromycin (ERT). In seedlings kept 120 h under continuous FR light, ALAD is detected in cytoplasm too, but also in etioplasts. Studies from DEAE-cellulose chromatography show that, when ALAD is localised in the cytoplasm it has a stable charge, but an unstable molecular weight. If plastids are allowed to grow normally under continuous FR light, the enzyme can be purified from stroma of etioplasts from 72 h from sowing. The molecule is unstable, both in charge and in molecular weight. ALAD from etioplasts is further transformed into a species stable both in charge and in molecular weight. The relationship between the molecular modifications and physiological results observed previously are discussed. 12 refs.

  16. Ultra-high Efficiency DC-DC Converter using GaN Devices

    DEFF Research Database (Denmark)

    Ramachandran, Rakesh

    2016-01-01

    properties of GaN devices can be utilized in power converters to make them more compact and highly efficient. This thesis entitled “Ultra-high Efficiency DC-DC Converter using GaN devices” focuses on achieving ultra-high conversion efficiency in an isolated dc-dc converter by the optimal utilization of Ga...... for many decades. However, the rate of improvement slowed as the silicon power materials asymptotically approached its theoretical bounds. Compared to Si, wideband gap materials such as Silicon Carbide (SiC) and Gallium Nitride (GaN) are promising semiconductors for power devices due to their superior...... in this thesis. Efficiency measurements from the hardware prototype of both the topologies are also presented in this thesis. Finally, the bidirectional operation of an optimized isolated dc-dc converter is presented. The optimized converter has achieved an ultra-high efficiency of 98.8% in both directions...

  17. Laser beam welding of new ultra-high strength and supra-ductile steels

    Science.gov (United States)

    Dahmen, Martin

    2015-03-01

    Ultra-high strength and supra-ductile are entering fields of new applications. Those materials are excellent candidates for modern light-weight construction and functional integration. As ultra-high strength steels the stainless martensitic grade 1.4034 and the bainitic steel UNS 53835 are investigated. For the supra-ductile steels stand two high austenitic steels with 18 and 28 % manganese. As there are no processing windows an approach from the metallurgical base on is required. Adjusting the weld microstructure the Q+P and the QT steels require weld heat treatment. The HSD steel is weldable without. Due to their applications the ultra-high strength steels are welded in as-rolled and strengthened condition. Also the reaction of the weld on hot stamping is reflected for the martensitic grades. The supra-ductile steels are welded as solution annealed and work hardened by 50%. The results show the general suitability for laser beam welding.

  18. Study on creep of fiber reinforced ultra-high strength concrete based on strength

    Science.gov (United States)

    Peng, Wenjun; Wang, Tao

    2018-04-01

    To complement the creep performance of ultra-high strength concrete, the long creep process of fiber reinforced concrete was studied in this paper. The long-term creep process and regularity of ultra-high strength concrete with 0.5% PVA fiber under the same axial compression were analyzed by using concrete strength (C80/C100/C120) as a variable. The results show that the creep coefficient of ultra-high strength concrete decreases with the increase of concrete strength. Compared with ACI209R (92), GL2000 models, it is found that the predicted value of ACI209R (92) are close to the experimental value, and the creep prediction model suitable for this experiment is proposed based on ACI209R (92).

  19. Generation of Ultra-high Intensity Laser Pulses

    International Nuclear Information System (INIS)

    Fisch, N.J.; Malkin, V.M.

    2003-01-01

    Mainly due to the method of chirped pulse amplification, laser intensities have grown remarkably during recent years. However, the attaining of very much higher powers is limited by the material properties of gratings. These limitations might be overcome through the use of plasma, which is an ideal medium for processing very high power and very high total energy. A plasma can be irradiated by a long pump laser pulse, carrying significant energy, which is then quickly depleted in the plasma by a short counterpropagating pulse. This counterpropagating wave effect has already been employed in Raman amplifiers using gases or plasmas at low laser power. Of particular interest here are the new effects which enter in high power regimes. These new effects can be employed so that one high-energy optical system can be used like a flashlamp in what amounts to pumping the plasma, and a second low-power optical system can be used to extract quickly the energy from the plasma and focus it precisely. The combined system can be very compact. Thus, focused intensities more than 10 25 W/cm 2 can be contemplated using existing optical elements. These intensities are several orders of magnitude higher than what is currently available through chirped pump amplifiers

  20. Design and Implementation of Wideband Exciter for an Ultra-high Resolution Airborne SAR System

    Directory of Open Access Journals (Sweden)

    Jia Ying-xin

    2013-03-01

    Full Text Available According to an ultra-high resolution airborne SAR system with better than 0.1 m resolution, a wideband Linear Frequency Modulated (LFM pulse compression exciter with 14.8 GHz carrier and 3.2 GHz bandwidth is designed and implemented. The selection of signal generation scheme and some key technique points for wideband LFM waveform is presented in detail. Then, an acute test and analysis of the LFM signal is performed. The final airborne experiments demonstrate the validity of the LFM source which is one of the subsystems in an ultra-high resolution airborne SAR system.

  1. All-optical ultra-high-speed OFDM to Nyquist-WDM conversion

    DEFF Research Database (Denmark)

    Guan, Pengyu; Røge, Kasper Meldgaard; Mulvad, Hans Christian Hansen

    2015-01-01

    We propose an all-optical ultra-high-speed OFDM to Nyquist-WDM conversion scheme based on complete OFT. An 8-subcarrier 640 Gbit/s DPSK OFDM super-channel is converted to eight 80-Gbit/s Nyquist-WDM channels with BER <10−9 performance for all channels.......We propose an all-optical ultra-high-speed OFDM to Nyquist-WDM conversion scheme based on complete OFT. An 8-subcarrier 640 Gbit/s DPSK OFDM super-channel is converted to eight 80-Gbit/s Nyquist-WDM channels with BER

  2. Intervention in individuals at ultra-high risk for psychosis: a review and future directions

    DEFF Research Database (Denmark)

    McGorry, Patrick D; Nelson, Barnaby; Amminger, G Paul

    2009-01-01

    OBJECTIVE: Over the last 15 years, a focus on early intervention in psychotic disorders has emerged. Initially, the early psychosis movement focused on timely recognition and phase-specific treatment of first-episode psychosis. However, early psychosis researchers suspected that pushing the point...... of intervention even further back to the prodromal phase of psychotic disorders may result in even better outcomes. This article reviews intervention research in the ultra-high-risk phase of psychotic disorders. DATA SOURCES: A literature search of intervention trials with ultra-high-risk cohorts published after...

  3. Ultra-High-Efficiency Apodized Grating Coupler Using a Fully Etched Photonic Crystal

    DEFF Research Database (Denmark)

    Ding, Yunhong; Peucheret, Christophe; Ou, Haiyan

    2013-01-01

    We demonstrate an apodized fiber-to-chip grating coupler using fully etched photonic crystal holes on the silicon-on-insulator platform. An ultra-high coupling efficiency of 1.65 dB (68%) with 3 dB bandwidth of 60 nm is experimentally demonstrated.......We demonstrate an apodized fiber-to-chip grating coupler using fully etched photonic crystal holes on the silicon-on-insulator platform. An ultra-high coupling efficiency of 1.65 dB (68%) with 3 dB bandwidth of 60 nm is experimentally demonstrated....

  4. Improvement of polyethylene by irradiation in artificial joints

    International Nuclear Information System (INIS)

    Oonishi, H.; Takayama, Y.

    1992-01-01

    The decrease in socket thickness of several total hip prostheses was measured on X-ray film. The following prostheses were compared: (1) SOM ''28 mm metal head and an ultra-high-molecular-weight-polyethylene (UHMWPE) socket irradiated with 10 8 rad of γ-radiation'', (2) T-28 ''28 mm metal head and a UHMWPE socket not irradiated'', (3) Bioceram ''28 mm alumina head and UHMWPE not irradiated'' and (4) irradiated Bioceram ''28 mm alumina head and UHMWPE socket irradiated with 10 8 rad of γ-radiation''. The average steady state wear rate of SOM, T-28, Bioceram and irradiated Bioceram were 0.076, 0.247, 0.098 and 0.072 mm/year, respectively. The weight bearing portion of the irradiated socket presented a clearly-outlined and irregular pattern of about 0.1 μm thickness having a smooth ripple surface. The scratch and holding phenomenon characteristic of non-irradiated sockets was not observed at all. In our experimental tests using an IS sliding wear test machine, the wear measured as decrease of thickness was smallest at 10 8 rad, although there was an increase in the coefficient of friction. Our experimental and clinical findings suggest that the best total hip prosthesis at present is one with an alumina head and a UHMWPE socket irradiated with 10 8 rad of γ-radiation. (author)

  5. Correlating TEM images of damage in irradiated materials to molecular dynamics simulations

    International Nuclear Information System (INIS)

    Schaeublin, R.; Caturla, M.-J.; Wall, M.; Felter, T.; Fluss, M.; Wirth, B.D.; Diaz de la Rubia, T.; Victoria, M.

    2002-01-01

    TEM image simulations are used to couple the results from molecular dynamics (MD) simulations to experimental TEM images. In particular we apply this methodology to the study of defects produced during irradiation. MD simulations have shown that irradiation of FCC metals results in a population of vacancies and interstitials forming clusters. The limitation of these simulations is the short time scales available, on the order of 100 s of picoseconds. Extrapolation of the results from these short times to the time scales of the laboratory has been difficult. We address this problem by two methods: we perform TEM image simulations of MD simulations of cascades with an improved technique, to relate defects produced at short time scales with those observed experimentally at much longer time scales. On the other hand we perform in situ TEM experiments of Au irradiated at liquid-nitrogen temperatures, and study the evolution of the produced damage as the temperature is increased to room temperature. We find that some of the defects observed in the MD simulations at short time scales using the TEM image simulation technique have features that resemble those observed in laboratory TEM images of irradiated samples. In situ TEM shows that stacking fault tetrahedra are present at the lowest temperatures and are stable during annealing up to room temperature, while other defect clusters migrate one dimensionally above -100 deg. C. Results are presented here

  6. ESSENSE: Ultra high resolution spectroscopy for the ESS

    International Nuclear Information System (INIS)

    Pasini, Stefano; Monkenbusch, Michael; Kozielewski, Tadeusz

    2016-01-01

    The instrument concept for a very high intensity neutron spin-echo spectrometer with ultimate resolution properties has been developed and submitted as an instrument proposal to ESS. Effective intensity gain factors up to 30 compared to the best current instruments are anticipated. In addition the resolution will be boosted to the technical limits by newly designed superconducting precession solenoids. The intensity gain results from the use of an optimized guide transporting the high flux from the ESS cold moderator on the one side and from the utilization of an extended wavelength frame of 8 Å yielding a multiplication of information collection rate on the other side. The instrument thus enables novel views on soft matter systems ranging from polymers, functional gels and more to to dynamics of biological molecules with relevance for MD development; the employment of new techniques for surface NSE (GINSE) may contribute to new knowledge in tribology and lubrication and other surface phenomena that currently are hampered by low intensity. New developments in “intelligent” polymers as e.g. self-healing, the properties of which depend on molecular mobility and dynamics, require observation at many 100 ns of correlation times with high intensity, which can be made with ESSENSE. (paper)

  7. Ultra-high sensitivity imaging of cancer using SERRS nanoparticles

    Science.gov (United States)

    Kircher, Moritz F.

    2016-05-01

    "Surface-enhanced Raman spectroscopy" (SERS) nanoparticles have gained much attention in recent years for in silico, in vitro and in vivo sensing applications. Our group has developed novel generations of biocompatible "surfaceenhanced resonance Raman spectroscopy" (SERRS) nanoparticles as novel molecular imaging agents. Via rigorous optimization of the different variables contributing to the Raman enhancement, we were able to design SERRS nanoparticles with so far unprecedented sensitivity of detection under in vivo imaging conditions (femto-attomolar range). This has resulted in our ability to visualize, with a single nanoparticle, many different cancer types (after intravenous injection) in mouse models. The cancer types we have tested so far include brain, breast, esophagus, stomach, pancreas, colon, sarcoma, and prostate cancer. All mouse models used are state-of-the-art and closely mimic the tumor biology in their human counterparts. In these animals, we were able to visualize not only the bulk tumors, but importantly also microscopic extensions and locoregional satellite metastases, thus delineating for the first time the true extent of tumor spread. Moreover, the particles enable the detection of premalignant lesions. Given their inert composition they are expected to have a high chance for clinical translation, where we envision them to have an impact in various scenarios ranging from early detection, image-guidance in open or minimally invasive surgical procedures, to noninvasive imaging in conjunction with spatially offset (SESORS) Raman detection devices.

  8. Molecular structure effects on the post irradiation diffusion in polymer gel dosimeters

    Energy Technology Data Exchange (ETDEWEB)

    Mattea, F.; Romero, M.; Strumia, M. [Instituto Multidisciplinario de Biologia Vegetal / CONICET, Universidad Nacional de Cordoba, Departamento de Quimica Organica, Ciudad Universitaria, 5000 Cordoba (Argentina); Vedelago, J. [Laboratorio de Investigaciones e Instrumentacion en Fisica Aplicada a la Medicina e Imagenes por Rayos X, Laboratorio 448 FaMAF - UNC, Ciudad Universitaria, 5000 Cordoba (Argentina); Quiroga, A. [Centro de Investigacion y Estudios de Matematica / CONICET, Oficina 318 FaMAF - UNC, Ciudad Universitaria, 5000 Cordoba (Argentina); Valente, M., E-mail: fmattea@gmail.com [Instituto de Fisica E. Gaviola / CONICET, LIIFAMIRx, Oficina 102 FaMAF - UNC, 5000 Cordoba (Argentina)

    2014-08-15

    Polymer gel dosimeters have specific advantages for recording 3D radiation dose distribution representing a key factor for most of the therapeutic and diagnostic radiation techniques. Radiation-induced polymerization and crosslinking reactions that take place in the dosimeter have been studied for different monomers like acrylamide and N,N-methylene-bis acrylamide (Bis) and most recently for less toxic monomers like N-isopropylacrylamide and Bis. In this work a novel system based on itaconic acid and Bis is proposed, the radical polymerization or gel formation of these monomers has been already studied for the formation of an hydrogel for non dosimetric applications and their reactivity are comparable with the already mentioned systems. Although the 3D structure is maintained after the dosimeter has been irradiated, it is not possible to eliminate the diffusion of the reacted and monomer species in regions of dose gradients within the gel after irradiation. As a consequence the dose information of the dosimeters loose quality over time. The mobility within the gelatin structure of the already mentioned species is related to their chemical structure, and nature. In this work the effect of changes in the chemical structure of the monomers over the dosimetric sensitivity and over the post-irradiation diffusion of species is studied. One of the acrylic acid groups of the itaconic acid molecule is modified to obtain molecules with similar reactivity but different molecular sizes. Dosimetric systems with these modified species, Bis, an antioxidant to avoid oxygen polymerization inhibition, water and gelatin are irradiated in an X-ray tomography at different doses, and the resulting dosimeters are characterized by Raman spectroscopy and optical absorbance to study their feasibility and capabilities as dosimetric systems, and by optical-CT to analyze the diffusion degree after being irradiated. (Author)

  9. Molecular structure effects on the post irradiation diffusion in polymer gel dosimeters

    International Nuclear Information System (INIS)

    Mattea, F.; Romero, M.; Strumia, M.; Vedelago, J.; Quiroga, A.; Valente, M.

    2014-08-01

    Polymer gel dosimeters have specific advantages for recording 3D radiation dose distribution representing a key factor for most of the therapeutic and diagnostic radiation techniques. Radiation-induced polymerization and crosslinking reactions that take place in the dosimeter have been studied for different monomers like acrylamide and N,N-methylene-bis acrylamide (Bis) and most recently for less toxic monomers like N-isopropylacrylamide and Bis. In this work a novel system based on itaconic acid and Bis is proposed, the radical polymerization or gel formation of these monomers has been already studied for the formation of an hydrogel for non dosimetric applications and their reactivity are comparable with the already mentioned systems. Although the 3D structure is maintained after the dosimeter has been irradiated, it is not possible to eliminate the diffusion of the reacted and monomer species in regions of dose gradients within the gel after irradiation. As a consequence the dose information of the dosimeters loose quality over time. The mobility within the gelatin structure of the already mentioned species is related to their chemical structure, and nature. In this work the effect of changes in the chemical structure of the monomers over the dosimetric sensitivity and over the post-irradiation diffusion of species is studied. One of the acrylic acid groups of the itaconic acid molecule is modified to obtain molecules with similar reactivity but different molecular sizes. Dosimetric systems with these modified species, Bis, an antioxidant to avoid oxygen polymerization inhibition, water and gelatin are irradiated in an X-ray tomography at different doses, and the resulting dosimeters are characterized by Raman spectroscopy and optical absorbance to study their feasibility and capabilities as dosimetric systems, and by optical-CT to analyze the diffusion degree after being irradiated. (Author)

  10. [Reparative Osteogenesis and Angiogenesis in Low Intensity Electromagnetic Radiation of Ultra-High Frequency].

    Science.gov (United States)

    Iryanov, Y M; Kiryanov, N A

    2015-01-01

    Non-drug correction of reparative bone tissue regeneration in different pathological states - one of the most actual problems of modern medicine. Our aim was to conduct morphological analysis of the influence of electromagnetic radiation of ultra-high frequency and low intensity on reparative osteogenesis and angiogenesis in fracture treatment under transosseous osteosynthesis. A controlled nonrandomized study was carried out. In the experiment conducted on rats we modeled tibial fracture with reposition and fixation of the bone fragments both in control and experimental groups. In the animals of the experimental group the fracture zone was exposed to low intensity electromagnetic radiation of ultra-high frequency. Exposure simulation was performed in the control group. The operated bones were examined using radiography, light and electronic microscopy, X-ray electronic probe microanalysis. It has been established that electromagnetic radiation of ultra-high frequency sessions in fracture treatment stimulate secretory activity and degranulation of mast cells, produce microcirculatory bed vascular permeability increase, endotheliocyte migration phenotype expression, provide endovascular endothelial outgrowth formation, activate reparative osteogenesis and angiogenesis while fracture reparation becomes the one of the primary type. The full periosteal, intermediary and intraosteal bone union was defined in 28 days. Among the therapeutic benefits of electromagnetic radiation of ultra-high frequency in fracture treatment we can detect mast cell secretorv activity stimulation and endovascular anziozenesis activation.

  11. Bond behavior of reinforcing steel in ultra-high performance concrete.

    Science.gov (United States)

    2014-10-01

    Ultra-High Performance Concrete (UHPC) is a relatively new class of advanced cementitious composite : materials, which exhibits high compressive [above 21.7 ksi (150 MPa)] and tensile [above 0.72 ksi (5 MPa)] : strengths. The discrete steel fiber rei...

  12. Case study: dairies utilizing ultra-high stocking density grazing in Pennsylvania and New York

    Science.gov (United States)

    Ultra-high stocking density (UHSD) grazing has gained interest in the forage industry. Proponents of UHSD emphasize increased forage use efficiency and soil improvement by grazing mature forage with stocking densities up to 560,425 kg ha**-1 of beef cattle on small paddocks with rest periods of up t...

  13. Ultra high energy cosmic rays above 10 GeV: Hints to new physics ...

    Indian Academy of Sciences (India)

    Ultra high energy cosmic rays; physics beyond standard model. ... The origin of the observed cosmic ray (CR) events above 10ѕј eV — the so-called ex- .... to arise simply from decay of some supermassive particles (of mass> 10ѕЅ eV) ...

  14. Ultra-high aspect ratio replaceable AFM tips using deformation-suppressed focused ion beam milling

    DEFF Research Database (Denmark)

    Savenko, Alexey; Yildiz, Izzet; Petersen, Dirch Hjorth

    2013-01-01

    Fabrication of ultra-high aspect ratio exchangeable and customizable tips for atomic force microscopy (AFM) using lateral focused ion beam (FIB) milling is presented. While on-axis FIB milling does allow high aspect ratio (HAR) AFM tips to be defined, lateral milling gives far better flexibility...

  15. Solutions for ultra-high speed optical wavelength conversion and clock recovery

    DEFF Research Database (Denmark)

    Oxenløwe, Leif Katsuo; Galili, Michael; Mulvad, Hans Christian Hansen

    2006-01-01

    This paper reports on our recent advances in ultra-fast optical communications relying on ultra-short pulses densely stacked in ultra-high bit rate serial data signals at a single wavelength. The paper describes details in solutions for the network functionalities of wavelength conversion and clock...... recovery at bit rates up to 320 Gb/s...

  16. Social cognition in patients at ultra-high risk for psychosis

    DEFF Research Database (Denmark)

    Glenthøj, Louise B.; Fagerlund, Birgitte; Hjorthøj, Carsten

    2016-01-01

    Objective: Patients at ultra-high risk (UHR) for psychosis show significant impairments in functioning. It is essential to determine which factors influence functioning, as it may have implications for intervention strategies. This study examined whether social cognitive abilities and clinical...

  17. Overview of lunar detection of ultra-high energy particles and new plans for the SKA

    NARCIS (Netherlands)

    James, Clancy W.; Alvarez-Muñiz, Jaime; Bray, Justin D.; Buitink, Stijn; Dagkesamanskii, Rustam D.; Ekers, Ronald D.; Falcke, Heino; Gayley, Ken; Huege, Tim; Mevius, Maaijke; Mutel, Rob; Scholten, Olaf; Spencer, Ralph; ter Veen, Sander; Winchen, Tobias

    2017-01-01

    The lunar technique is a method for maximising the collection area for ultra-high-energy (UHE) cosmic ray and neutrino searches. The method uses either ground-based radio telescopes or lunar orbiters to search for Askaryan emission from particles cascading near the lunar surface. While experiments

  18. Ultra-high efficiency, fast graphene micro-heater on silicon

    DEFF Research Database (Denmark)

    Yan, Siqi; Zhu, Xiaolong; Frandsen, Lars Hagedorn

    2017-01-01

    We demonstrate an ultra-high efficiency and fast graphene microheater on silicon photonic crystal waveguide. By taking advantage of slow-light effect, a tuning efficiency of 1.07 nm/mW and power consumption per free spectral range of 3.99 mW. A fast rise and decay times (10% to 90%) of only 750 ns...

  19. OTR profile measurement of a LINAC electron beam with portable ultra high-speed camera

    International Nuclear Information System (INIS)

    Mogi, T.; Nisiyama, S.; Tomioka, S.; Enoto, T.

    2004-01-01

    We have studied on and developed a portable ultra high-speed camera, and so applied to measurement of a LINAC electron beam. We measured spatial OTR profiles of a LINAC electron beam using this camera with temporal resolution 80ns. (author)

  20. 78 FR 70567 - Nationwide Use of High Frequency and Ultra High Frequency Active SONAR Technology; Final...

    Science.gov (United States)

    2013-11-26

    ... Frequency and Ultra High Frequency Active SONAR Technology; Final Programmatic Environmental Assessment and... each alternative on the human and natural environments. FOR FURTHER INFORMATION CONTACT: If you have... Programmatic Environmental Assessment The scope of the PEA focuses on potential impacts associated with the...

  1. Detection of ultra-high energy cosmic ray showers with a single-pixel fluorescence telescope

    Czech Academy of Sciences Publication Activity Database

    Fujii, T.; Malacari, M.; Bertaina, M.; Casolino, E.; Dawson, B.; Horváth, P.; Hrabovský, M.; Jiang, J.; Mandát, Dušan; Matalon, A.; Matthews, J.N.; Motloch, P.; Palatka, Miroslav; Pech, Miroslav; Privitera, P.; Schovánek, Petr; Takizawa, Y.; Thomas, S.B.; Trávníček, Petr; Yamazaki, K.

    2016-01-01

    Roč. 74, Feb (2016), s. 64-72 ISSN 0927-6505 R&D Projects: GA MŠk(CZ) LG13007 Institutional support: RVO:68378271 Keywords : ultra-high energy cosmic rays * fluorescence detector * extensive air shower Subject RIV: BF - Elementary Particles and High Energy Physics Impact factor: 3.257, year: 2016

  2. The MIDAS telescope for microwave detection of ultra-high energy cosmic rays

    Czech Academy of Sciences Publication Activity Database

    Alvarez-Muñiz, J.; Soares, E.A.; Berlin, A.; Bogdan, M.; Boháčová, Martina; Bonifazi, C.; Carvalho, W.R.; de Mello Neto, J.R.T.; San Luis, P.F.; Genat, J.F.; Hollon, N.; Mills, E.; Monasor, M.; Privitera, P.; Ramos de Castro, A.; Reyes, L.C.; Richardson, M.; Rouille D’Orfeuil, B.; Santos, E.M.; Wayne, S.; Williams, C.; Zas, E.; Zhou, J.

    2013-01-01

    Roč. 719, Aug (2013), s. 70-80 ISSN 0168-9002 Institutional support: RVO:68378271 Keywords : ultra high energy cosmic rays * radio-detection * microwave * GHz Subject RIV: BF - Elementary Particles and High Energy Physics Impact factor: 1.316, year: 2013

  3. Deformation and degradation of polymers in ultra-high-pressure liquid chromatography

    NARCIS (Netherlands)

    Uliyanchenko, E.; van der Wal, S.; Schoenmakers, P.J.

    2011-01-01

    Ultra-high-pressure liquid chromatography (UHPLC) using columns packed with sub-2 μm particles has great potential for separations of many types of complex samples, including polymers. However, the application of UHPLC for the analysis of polymers meets some fundamental obstacles. Small particles

  4. Fornax A, Centaurus A other radio galaxies as sources of ultra-high energy cosmic rays

    Science.gov (United States)

    Matthews, J. H.; Bell, A. R.; Blundell, K. M.; Araudo, A. T.

    2018-06-01

    The origin of ultra-high energy cosmic rays (UHECRs) is still unknown. It has recently been proposed that UHECR anisotropies can be attributed to starburst galaxies or active galactic nuclei. We suggest that the latter is more likely and that giant-lobed radio galaxies such as Centaurus A and Fornax A can explain the data.

  5. Kinetic and thermodynamic analysis of ultra-high pressure and heat ...

    African Journals Online (AJOL)

    Purpose: To undertake comparative kinetic and thermodynamic analyses of the interaction of bovine serum albumin (BSA) with IgG pre-treated with ultra-high pressure (UHP) and moderate heat. Methods: BSA solutions were processed at 100 – 600 MPa and 25 – 40 °C. We applied an optical biosensor based on surface ...

  6. Adaptive sensor-based ultra-high accuracy solar concentrator tracker

    Science.gov (United States)

    Brinkley, Jordyn; Hassanzadeh, Ali

    2017-09-01

    Conventional solar trackers use information of the sun's position, either by direct sensing or by GPS. Our method uses the shading of the receiver. This, coupled with nonimaging optics design allows us to achieve ultra-high concentration. Incorporating a sensor based shadow tracking method with a two stage concentration solar hybrid parabolic trough allows the system to maintain high concentration with acute accuracy.

  7. THE MOLECULAR EMISSION OF THE IRRADIATED STAR-FORMING CORE AHEAD OF HH 80N

    International Nuclear Information System (INIS)

    Masque, Josep M.; Beltran, Maria T.; Estalella, Robert; Girart, Josep M.; Viti, Serena

    2009-01-01

    We present a Berkeley-Illinois-Maryland Association Array molecular survey of the star-forming core ahead of HH 80N, the optically obscured northern counterpart of the Herbig-Haro objects HH 80/81. Continuum emission at 1.4 mm and 8 μm is detected at the center of the core, which confirms the presence of an embedded very young stellar object in the core. All detected molecular species arise in a ringlike structure, which is most clearly traced by CS (2-1) emission. This molecular ring suggests that strong molecular depletion occurs in the inner part of the core (at a radius of ≅0.1 pc and densities higher than ∼5 x 10 4 cm -3 ). Despite the overall morphology and kinematic similarity between the different species, there is significant molecular differentiation along the ringlike structure. The analysis of the chemistry along the core shows that part of this differentiation may be caused by the UV irradiation of the nearby HH 80N object that illuminates the part of the core facing HH 80N, which results in an abundance enhancement of some of the detected species.

  8. Effect of gamma-irradiation on rice seed DNA. Pt. 1. Yield and molecular size of DNA extracted from irradiated rice seeds

    International Nuclear Information System (INIS)

    Kawamura, Yoko; Konishi, Akihiro; Yamada, Takashi; Saito, Yukio

    1995-01-01

    The effect of gamma-irradiation on the DNA of hulled rice seeds was investigated. The cetyltrimethylammonium bromide (CTAB) method was preferred for the extraction of DNA from rice seeds because of its high quality and good yield. The yield of DNA that was determined by gel electrophoresis, decreased as the irradiation dose increased from 1 kGy. DNA extracted from rice seeds irradiated with a 30 kGy dose showed a molecular size of less than 20 kb, while that from unirradiated rice showed more than 100 kb in electrophoretic profiles. It can be assumed that the decrease in yield was mainly induced by the crosslinking between protein and DNA, and the reduction in molecular size was induced by double-strand breaks. (J.P.N.)

  9. Irradiation of tungsten with metallic diatomic molecular ions: atomic-resolution observations of depleted zones

    International Nuclear Information System (INIS)

    Pramanik, D.; Seidman, D.N.

    1982-08-01

    Direct evidence, on an atomic scale, is presented for the enhancement of damage production per projectile ion in diatomic metallic molecular ion (dimer) irradiations of tungsten as compared to monatomic metallic ion (monomer) irradiations. Irradiations were performed in situ at less than or equal to 10 K, in a field-ion microscope, employing 20 keV Ag + or W + monomer ions and the results are compared with 40 keV W 2 + or Ag 2 + dimer ion bombardments; the average energy per ion was 20 keV. First, in the near-surface region the depleted zones produced by the W 2 + dimer ions give rise to void-like contrast effects. The W + monomer ions do not produce this void-like damage. The existence of voids was explained employing a nucleation and diffusion-limited growth model which suggests that the growth can occur on a time scale -9 s, if the effective diffusivity of an atom in the fully-developed collision cascade is > 3 x 10 -4 cm 2 s -1 . Second, by counting the number of vacancies in individual depleted zones, produced by the different ions, it was demonstrated that the number of vacancies produced per incoming ion of the dimer is 1.55 times greater than the number of vacancies produced per monomer ion

  10. The Heart of China revisited: II Early Paleozoic (ultra)high-pressure and (ultra)high-temperature metamorphic Qinling orogenic collage

    Science.gov (United States)

    Bader, Thomas; Franz, Leander; Ratschbacher, Lothar; de Capitani, Christian; Webb, A. Alexander G.; Yang, Zhao; Pfänder, Jörg A.; Hofmann, Mandy; Linnemann, Ulf

    2013-07-01

    Orogens with multiple (ultra)high-pressure ((U)HP) and (ultra)high-temperature ((U)HT) metamorphic events provide a complex but telling record of oceanic and continental interaction. The Early Paleozoic history of the "Heart of China," the Qinling orogenic collage, offers snapshots of at least three (U)HP and two (U)HT metamorphic events. The preservation of remnants of both oceanic and continental domains together with a ≥110 Myr record of magmatism allows the reconstruction of the processes that resulted in this disparate metamorphism. Herein, we first illuminate the pressure-temperature-time (P-T-t) evolution of the Early Paleozoic (U)HP and (U)HT events by refining the petrographic descriptions and P-T estimates, assess published, and employ new U/Th-Pb zircon, monazite, and titanite, and 40Ar-39Ar phengite geochronology to date the magmatic and metamorphic events. Then we explore how the metamorphic and magmatic events are related tectonically and how they elucidate the affinities among the various complexes in the Qinling orogenic collage. We argue that a Meso-Neoproterozoic crustal fragment—the Qinling complex—localized subduction-accretion events that involved subduction, oceanic-arc formation, and back-arc spreading along its northern margin, and mtantle-wedge exhumation and spreading-ridge subduction along its southern margin.

  11. Ultra high vacuum activities and required modification at 14 UD BARC-TIFR pelletron accelerator facility

    International Nuclear Information System (INIS)

    Sharma, S.C.; Ninawe, N.G.; Ramjilal; Bhagwat, P.V.; Salvi, S.B.

    2003-01-01

    Full text: The 14 UD pelletron accelerator is working round the clock since 1989. The accelerator is housed inside a tank which is 6 meter in diameter and 25 meter long. The accelerator tank is pressurized with SF 6 at 80 to 100 PSIG in order to achieve 14MV. In pelletron, ions are extracted from SNICS are pre-accelerated up to 300 keV before being injected into low energy accelerator tube. In the terminal which is at high potential (4MV to 14 MV), the ion beam pass through the stripper and positive ions with high charge states are produced. The high energy beams are focussed and analyzed by 90 deg magnet. The analyzed beam is then transported to the various experimental ports. In order to achieve uniform ultra high vacuum (to reduce the loss of intensity and spread in the energy of ions beams) in more than 100 metre and 100 mm diameter beam lines including magnet chambers and various beam diagnostic devices, combination of getter-ion pumps and turbo pumps are being used at Pelletron Accelerator Facility. The 14 UD pelletron is equipped with a combination of foil and gas stripper in high voltage terminal section. The foil and gas stripper in the terminal section are mainly used for stripping of light and heavy ions respectively. The gas stripper plays a great role for stripping of heavy ions and its efficiency depends on gas stripper parameters and supporting pumps. The gas stripper is originally installed with getter pumps. These pumps required periodic replacement of titanium cartridges and slowly the pumping speed used to diminish with time. A new recirculation turbo molecular pumps based system is being designed to improve good beam transmission. Details of design will be presented. Proton beam of tens of MeV energy and μA range current is in demand to carry out specific radiochemistry experiments in this facility. It is proposed to built and accommodate a proton experimental setup in the tower area of the existing facility. Details of required UHV system for

  12. Ultra-high mechanical properties of porous composites based on regenerated cellulose and cross-linked poly(ethylene glycol).

    Science.gov (United States)

    Teng, Jian; Yang, Biao; Zhang, Liang-Qing; Lin, Sheng-Qiang; Xu, Ling; Zhong, Gan-Ji; Tang, Jian-Hua; Li, Zhong-Ming

    2018-01-01

    The ultra-high mechanical, biocompatible and biodegradable porous regenerated cellulose/poly(ethylene glycol) (RC/PEG) composites with double network structure were fabricated via an simple method to dissolve cellulose followed by UV irradiation. The porous structure of RC/PEG was sensitively altered by PEG contents, which led to the porous structure morphology transition from 3D fibrillar network to close-grained sheet-like-network with the loading of cross-linked PEG. The porous RC/PEG showed excellent mechanical properties, i.e., the compressive strength can reach 33 times higher than that of neat RC (0.07MPa) at the compressive strain of 30%. Porous RC/PEG also displayed outstanding properties with openly porous structure and structural stabilization. Besides, porous RC/PEG exhibited good water absorbency, which the water absorbency ratio at equilibrium state was 83% higher than that of porous RC. This work provides an environmentally friendly and simple pathway to prepare non-toxic and biocompatible porous regenerated cellulose-based composites with high strength, structural stabilization and good water absorbency, which could be useful for packaging, biomedical applications, sewage purification, etc. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Changes in mitochondrial functioning with electromagnetic radiation of ultra high frequency as revealed by electron paramagnetic resonance methods.

    Science.gov (United States)

    Burlaka, Anatoly; Selyuk, Marina; Gafurov, Marat; Lukin, Sergei; Potaskalova, Viktoria; Sidorik, Evgeny

    2014-05-01

    To study the effects of electromagnetic radiation (EMR) of ultra high frequency (UHF) in the doses equivalent to the maximal permitted energy load for the staffs of the radar stations on the biochemical processes that occur in the cell organelles. Liver, cardiac and aorta tissues from the male rats exposed to non-thermal UHF EMR in pulsed and continuous modes were studied during 28 days after the irradiation by the electron paramagnetic resonance (EPR) methods including a spin trapping of superoxide radicals. The qualitative and quantitative disturbances in electron transport chain (ETC) of mitochondria are registered. A formation of the iron-nitrosyl complexes of nitric oxide (NO) radicals with the iron-sulphide (FeS) proteins, the decreased activity of FeS-protein N2 of NADH-ubiquinone oxidoreductase complex and flavo-ubisemiquinone growth combined with the increased rates of superoxide production are obtained. (i) Abnormalities in the mitochondrial ETC of liver and aorta cells are more pronounced for animals radiated in a pulsed mode; (ii) the alterations in the functioning of the mitochondrial ETC cause increase of superoxide radicals generation rate in all samples, formation of cellular hypoxia, and intensification of the oxide-initiated metabolic changes; and (iii) electron paramagnetic resonance methods could be used to track the qualitative and quantitative changes in the mitochondrial ETC caused by the UHF EMR.

  14. Enhancing ultra-high CPV passive cooling using least-material finned heat sinks

    Energy Technology Data Exchange (ETDEWEB)

    Micheli, Leonardo, E-mail: lm409@exeter.ac.uk; Mallick, Tapas K., E-mail: T.K.Mallick@exeter.ac.uk [Environment and Sustainability Institute, University of Exeter, Penryn, Cornwall TR10 9FE (United Kingdom); Fernandez, Eduardo F., E-mail: E.Fernandez-Fernandez2@exeter.ac.uk [Environment and Sustainability Institute, University of Exeter, Penryn, Cornwall TR10 9FE (United Kingdom); Centre of Advanced Studies in Energy and Environment, University of Jaen, Jaen 23071 (Spain); Almonacid, Florencia, E-mail: facruz@ujaen.es [Centre of Advanced Studies in Energy and Environment, University of Jaen, Jaen 23071 (Spain); Reddy, K. S., E-mail: ksreddy@iitm.ac.in [Department of Mechanical Engineering, Indian Institute of Technology Madras, Chennai, 600036 (India)

    2015-09-28

    Ultra-high concentrating photovoltaic (CPV) systems aim to increase the cost-competiveness of CPV by increasing the concentrations over 2000 suns. In this work, the design of a heat sink for ultra-high concentrating photovoltaic (CPV) applications is presented. For the first time, the least-material approach, widely used in electronics to maximize the thermal dissipation while minimizing the weight of the heat sink, has been applied in CPV. This method has the potential to further decrease the cost of this technology and to keep the multijunction cell within the operative temperature range. The designing procedure is described in the paper and the results of a thermal simulation are shown to prove the reliability of the solution. A prediction of the costs is also reported: a cost of 0.151$/W{sub p} is expected for a passive least-material heat sink developed for 4000x applications.

  15. Study of application technology of ultra-high speed computer to the elucidation of complex phenomena

    International Nuclear Information System (INIS)

    Sekiguchi, Tomotsugu

    1996-01-01

    The basic design of numerical information library in the decentralized computer network was explained at the first step of constructing the application technology of ultra-high speed computer to the elucidation of complex phenomena. Establishment of the system makes possible to construct the efficient application environment of ultra-high speed computer system to be scalable with the different computing systems. We named the system Ninf (Network Information Library for High Performance Computing). The summary of application technology of library was described as follows: the application technology of library under the distributed environment, numeric constants, retrieval of value, library of special functions, computing library, Ninf library interface, Ninf remote library and registration. By the system, user is able to use the program concentrating the analyzing technology of numerical value with high precision, reliability and speed. (S.Y.)

  16. The Promise and Challenges of Ultra High Bypass Ratio Engine Technology and Integration

    Science.gov (United States)

    Hughes, Chris

    2011-01-01

    In this presentation, an overview of the research being conducted by the ERA Project in Ultra High Bypass aircraft propulsion and in partnership with Pratt & Whitney with their Geared TurboFan (GTF) is given. The ERA goals are shown followed by a discussion of what areas need to be addressed on the engine to achieve the goals and how the GTF is uniquely qualified to meet the goals through a discussion of what benefits the cycle provides. The first generation GTF architecture is then shown highlighting the areas of collaboration with NASA, and the fuel burn, noise and emissions reductions possible based on initial static ground test and flight test data of the first GTF engine. Finally, a 5 year technology roadmap is presented focusing on Ultra High Bypass propulsion technology research areas that are being pursued and being planned by ERA and P&W under their GTF program.

  17. Ultra-high density aligned Carbon-nanotube with controled nano-morphology for supercapacitors

    Science.gov (United States)

    Ghaffari, Mehdi; Zhao, Ran; Liu, Yang; Zhou, Yue; Cheng, Jiping; Guzman de Villoria, Roberto; Wardle, B. L.; Zhang, Q. M.

    2012-02-01

    Recent advances in fabricating controlled-morphology vertically aligned carbon nanotubes (VA-CNTs) with ultrahigh volume fractioncreate unique opportunities for developing unconventional supercapacitors with ultra-high energy density, power density, and long charge/discharge cycle life.Continuous paths through inter-VA-CNT channels allow fast ion transport, and high electrical conduction of the aligned CNTs in the composite electrodes lead to fast discharge speed. We investigate the charge-discharge characteristics of VA-CNTs with >20 vol% of CNT and ionic liquids as electrolytes. By employing both the electric and electromechanical spectroscopes, as well as nanostructured materials characterization, the ion transport and storage behaviors in porous electrodes are studied. The results suggest pathways for optimizing the electrode morphology in supercapacitorsusing ultra-high volume fraction VA-CNTs to further enhance performance.

  18. Processing and evaluation of the AGS Booster ultra-high vaccum system

    International Nuclear Information System (INIS)

    Hseuh, H.C.; Mapes, M.; Schnitzenbaumer, P.; Shen, B.; Sikora, R.; Stattel, P.

    1991-01-01

    The AGS Booster is a synchrotron for the acceleration of both protons and heavy ions. To minimize the beam loss due to charge exchange of the partially stripped, low Β very heavy ions with the residual gas molecules, pressure of low 10 -11 Torr is required for the 200 m booster ring. To achieve this ultra high vacuum, chemical cleaning, vacuum furnace degassing and insitu bake were employed for all chambers and beam components. Using these procedures, vacuums of low 10 -11 Torr have been routinely achieved during the testing of individual half cells and beam components, and during the commissioning of the vacuum sectors. In this paper, the design and layout of chambers, flanges and bakeout hardware is briefly described. The vacuum processing of different components and the results of bakeout and evaluation are summarized. The experience gained during the construction and commissioning of this ultra-high vacuum system is also given. 3 refs., 3 figs., 1 tab

  19. Cavity resonance absorption in ultra-high bandwidth CRT deflection structure by a resistive load

    Science.gov (United States)

    Dunham, M.E.; Hudson, C.L.

    1993-05-11

    An improved ultra-high bandwidth helical coil deflection structure for a cathode ray tube is described comprising a first metal member having a bore therein, the metal walls of which form a first ground plane; a second metal member coaxially mounted in the bore of the first metal member and forming a second ground plane; a helical deflection coil coaxially mounted within the bore between the two ground planes; and a resistive load disposed in one end of the bore and electrically connected to the first and second ground planes, the resistive load having an impedance substantially equal to the characteristic impedance of the coaxial line formed by the two coaxial ground planes to inhibit cavity resonance in the structure within the ultra-high bandwidth of operation. Preferably, the resistive load comprises a carbon film on a surface of an end plug in one end of the bore.

  20. Ultra-high temperature tensile properties of ODS steel claddings under severe accident conditions

    Energy Technology Data Exchange (ETDEWEB)

    Yano, Y., E-mail: yano.yasuhide@jaea.go.jp [Japan Atomic Energy Agency, 4002, Narita-cho, Oarai-machi, Ibaraki, 311-1393 (Japan); Tanno, T.; Oka, H.; Ohtsuka, S.; Inoue, T.; Kato, S.; Furukawa, T.; Uwaba, T.; Kaito, T. [Japan Atomic Energy Agency, 4002, Narita-cho, Oarai-machi, Ibaraki, 311-1393 (Japan); Ukai, S.; Oono, N. [Materials Science and Engineering, Faculty of Engineering, Hokkaido University, N13, W-8, Kita-ku, Sapporo, Hokkaido, 060-8628 (Japan); Kimura, A. [Institute of Advanced Energy, Kyoto University, Gokasho, Uji, Kyoto 611-0011 (Japan); Hayashi, S. [Tokyo Institute of Technology, 2-12-1, Ookayama, Meguro-ku, Tokyo 152-8550 (Japan); Torimaru, T. [Nippon Nuclear Fuel Development Co., Ltd., 2163, Narita-cho, Oarai-machi, Ibaraki, 311-1313 (Japan)

    2017-04-15

    Ultra-high temperature ring tensile tests were performed to investigate the tensile behavior of oxide dispersion strengthened (ODS) steel claddings and wrapper materials under severe accident conditions with temperatures ranging from room temperature to 1400 °C which is close to the melting point of core materials. The experimental results showed that the tensile strength of 9Cr-ODS steel claddings was highest in the core materials at ultra-high temperatures of 900–1200 °C, but there was significant degradation in the tensile strength of 9Cr-ODS steel claddings above 1200 °C. This degradation was attributed to grain boundary sliding deformation with γ/δ transformation, which is associated with reduced ductility. By contrast, the tensile strength of recrystallized 12Cr-ODS and FeCrAl-ODS steel claddings retained its high value above 1200 °C, unlike the other tested materials.

  1. Ultra-high temperature tensile properties of ODS steel claddings under severe accident conditions

    Science.gov (United States)

    Yano, Y.; Tanno, T.; Oka, H.; Ohtsuka, S.; Inoue, T.; Kato, S.; Furukawa, T.; Uwaba, T.; Kaito, T.; Ukai, S.; Oono, N.; Kimura, A.; Hayashi, S.; Torimaru, T.

    2017-04-01

    Ultra-high temperature ring tensile tests were performed to investigate the tensile behavior of oxide dispersion strengthened (ODS) steel claddings and wrapper materials under severe accident conditions with temperatures ranging from room temperature to 1400 °C which is close to the melting point of core materials. The experimental results showed that the tensile strength of 9Cr-ODS steel claddings was highest in the core materials at ultra-high temperatures of 900-1200 °C, but there was significant degradation in the tensile strength of 9Cr-ODS steel claddings above 1200 °C. This degradation was attributed to grain boundary sliding deformation with γ/δ transformation, which is associated with reduced ductility. By contrast, the tensile strength of recrystallized 12Cr-ODS and FeCrAl-ODS steel claddings retained its high value above 1200 °C, unlike the other tested materials.

  2. Diamond dispersed cemented carbide produced without using ultra high pressure equipment

    International Nuclear Information System (INIS)

    Moriguchi, H.; Tsuzuki, K.; Ikegaya, A.

    2001-01-01

    We have developed a composite material of dispersed diamond particles in cemented carbide without using ultra high pressure equipment. The developed diamond dispersed cemented carbide combines the excellent properties of cemented carbide with diamond and also provides 1.5 times improved fracture toughness over that of cemented carbide. They also show 10 times higher wear resistance over that of cemented carbide in a wear resistance test against bearing steel, and 5 times greater grindability than diamond compacts. Because ultra high pressure equipment is not used to produce the developed material, large compacts over 100 mm in diameter can be manufactured. The developed material showed 10-25 times higher wear resistance in real use as wear-resistant tools such as centerless blades and work-rests. (author)

  3. Ultra-High Field Magnets for X-Ray and Neutron Scattering using High Temperature Superconductors

    Energy Technology Data Exchange (ETDEWEB)

    Winn, Barry L. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Broholm, C. [Johns Hopkins Univ., Baltimore, MD (United States); Bird, M. [Florida State Univ., Tallahassee, FL (United States). National High Magnetic Field Lab. (MagLab); Breneman, Bruce C. [General Atomics, San Diego, CA (United States); Coffey, Michael [Cryomagnetics, Oak Ridge, TN (United States); Cutler, Roy I. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Duckworth, Robert C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Erwin, R. [National Inst. of Standards and Technology (NIST), Gaithersburg, MD (United States); Hahn, Seungyong [Florida State Univ., Tallahassee, FL (United States). National High Magnetic Field Lab. (MagLab); Hernandez, Yamali [National Inst. of Standards and Technology (NIST), Gaithersburg, MD (United States); Herwig, Kenneth W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Holland, Leo D. [General Atomics, San Diego, CA (United States); Lonergan, Kevin M. [Oxford Instruments, Abingdon (United Kingdom); Melhem, Ziad [Oxford Instruments, Abingdon (United Kingdom); Minter, Stephen J. [Cryomagnetics, Oak Ridge, TN (United States); Nelson, C. [Brookhaven National Lab. (BNL), Upton, NY (United States); Paranthaman, M. Parans [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Pierce, Josh [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Ruff, Jacob [Cornell Univ., Ithaca, NY (United States); Shen, Tengming [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Sherline, Todd E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Smeibidl, Peter G. [Helmholtz-Zentrum Berlin (HZB), (Germany); Tennant, David [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); van der Laan, Danko [Advanced Conductor Technologies, LLC, Boulder, CO (United States); Wahle, Robert J. [Helmholtz-Zentrum Berlin (HZB), (Germany); Zhang, Yifei [SuperPower, Inc., Schenectady, NY (United States)

    2017-01-01

    X-ray and neutron scattering techniques are capable of acquiring information about the structure and dynamics of quantum matter. However, the high-field magnet systems currently available at x-ray and neutron scattering facilities in the United States are limited to fields of 16 tesla (T) at maximum, which precludes applications that require and/or study ultra-high field states of matter. This gap in capability—and the need to address it—is a central conclusion of the 2005 National Academy of Sciences report by the Committee on Opportunities in High Magnetic Field Science. To address this gap, we propose a magnet development program that would more than double the field range accessible to scattering experiments. With the development and use of new ultra-high field–magnets, the program would bring into view new worlds of quantum matter with profound impacts on our understanding of advanced electronic materials.

  4. Specific features of high-cycle and ultra-high-cycle fatigue

    Czech Academy of Sciences Publication Activity Database

    Lukáš, Petr; Kunz, Ludvík

    2002-01-01

    Roč. 25, - (2002), s. 747-753 ISSN 8756-758X R&D Projects: GA AV ČR KSK1010104; GA AV ČR IAA2041002 Institutional research plan: CEZ:AV0Z2041904 Keywords : ultra high cycle fatigue * fatigue mechanisms * cyclic plastic deformation Subject RIV: JL - Materials Fatigue, Friction Mechanics Impact factor: 0.701, year: 2002

  5. A novel ultra-high vacuum manipulator with six degrees of freedom

    International Nuclear Information System (INIS)

    Auciello, O.; Lulich, C.; Alonso, E.V.; Baragiola, R.A.

    1977-01-01

    An ultra-high vacuum goniometer of novel design for use in experiments with ion beams is described. The goniometer uses a wire system to transmit movements, is bakeable to 200 0 C and is reproducible in its angular positions to within 1.3 X 10 -4 rad (0.008 0 ). It allows a sample to be rotated around two axes over 360 0 , around a third over 180 0 , and to be translated along three perpendicular axes. (Auth.)

  6. Measurement of ultra-high energy cosmic rays: An experimental summary and prospects

    Directory of Open Access Journals (Sweden)

    Fukushima M.

    2013-06-01

    Full Text Available Measurements of Ultra-High Energy Cosmic Rays achieved remarkable progress in the last 10 years. Physicists, gathered from around the world in the symposium UHECR-2012 held at CERN on February 13-16 2012, reported their most up-to-date observations, discussed the meaning of their findings, and identified remaining problems and future challenges in this field. This paper is a part of the symposium proceedings on the experimental summary and future prospects of the UHECR study.

  7. Research and Application of WCF Technology in Data Acquisition of Ultra-high Speed Packaging Machine

    Directory of Open Access Journals (Sweden)

    Qian Jie

    2016-01-01

    Full Text Available By introducing WCF technology on data acquisition of ultra-high speed packaging machine, data acquisition system reads dates of machine in polling mode through the WCF client, which can achieve accurate data collection, and effectively isolate the data acquisition system and the machine control system. It enhances the security of data interaction between systems, but also reduces the coupling degree between systems.

  8. Inactivation of Bacillus spores inoculated in milk by Ultra High Pressure Homogenization.

    Science.gov (United States)

    Amador Espejo, Genaro Gustavo; Hernández-Herrero, M M; Juan, B; Trujillo, A J

    2014-12-01

    Ultra High-Pressure Homogenization treatments at 300 MPa with inlet temperatures (Ti) of 55, 65, 75 and 85 °C were applied to commercial Ultra High Temperature treated whole milk inoculated with Bacillus cereus, Bacillus licheniformis, Bacillus sporothermodurans, Bacillus coagulans, Geobacillus stearothermophilus and Bacillus subtilis spores in order to evaluate the inactivation level achieved. Ultra High-Pressure Homogenization conditions at 300 MPa with Ti = 75 and 85 °C were capable of a spore inactivation of ∼5 log CFU/mL. Furthermore, under these processing conditions, commercial sterility (evaluated as the complete inactivation of the inoculated spores) was obtained in milk, with the exception of G. stearothermophilus and B. subtilis treated at 300 MPa with Ti = 75 °C. The results showed that G. stearothermophilus and B. subtilis have higher resistance to the Ultra High-Pressure Homogenization treatments applied than the other microorganisms inoculated and that a treatment performed at 300 MPa with Ti = 85 °C was necessary to completely inactivate these microorganisms at the spore level inoculated (∼1 × 10(6) CFU/mL). Besides, a change in the resistance of B. licheniformis, B. sporothermodurans, G. stearothermophilus and B. subtilis spores was observed as the inactivation obtained increased remarkably in treatments performed with Ti between 65 and 75 °C. This study provides important evidence of the suitability of UHPH technology for the inactivation of spores in high numbers, leading to the possibility of obtaining commercially sterile milk. Copyright © 2014 Elsevier Ltd. All rights reserved.

  9. Patterns of white matter microstructure in individuals at ultra-high-risk for psychosis

    DEFF Research Database (Denmark)

    Krakauer, K; Ebdrup, B H; Glenthøj, B Y

    2017-01-01

    BACKGROUND: Individuals at ultra-high-risk (UHR) for psychosis present with emerging symptoms and decline in functioning. Previous univariate analyses have indicated widespread white matter (WM) aberrations in multiple brain regions in UHR individuals and patients with schizophrenia. Using multiv......, MO, and higher RD. CONCLUSIONS: UHR individuals demonstrate complex brain patterns of WM abnormalities. Despite the subtle psychopathology of UHR individuals, aberrations in WM appear associated with positive and negative symptoms as well as level of functioning....

  10. Ground Glass Pozzolan in Conventional, High, and Ultra-High Performance Concrete

    OpenAIRE

    Tagnit-Hamou Arezki; Zidol Ablam; Soliman Nancy; Deschamps Joris; Omran Ahmed

    2018-01-01

    Ground-glass pozzolan (G) obtained by grinding the mixed-waste glass to same fineness of cement can act as a supplementary-cementitious material (SCM), given that it is an amorphous and a pozzolanic material. The G showed promising performances in different concrete types such as conventional concrete (CC), high-performance concrete (HPC), and ultra-high performance concrete (UHPC). The current paper reports on the characteristics and performance of G in these concrete types. The use of G pro...

  11. RECENT ADVANCES IN ULTRA-HIGH PERFORMANCE LIQUID CHROMATOGRAPHY FOR THE ANALYSIS OF TRADITIONAL CHINESE MEDICINE

    Science.gov (United States)

    Huang, Huilian; Liu, Min; Chen, Pei

    2014-01-01

    Traditional Chinese medicine has been widely used for the prevention and treatment of various diseases for thousands of years in China. Ultra-high performance liquid chromatography (UHPLC) is a relatively new technique offering new possibilities. This paper reviews recent developments in UHPLC in the separation and identification, fingerprinting, quantification, and metabolism of traditional Chinese medicine. Recently, the combination of UHPLC with MS has improved the efficiency of the analysis of these materials. PMID:25045170

  12. Physics of Eclipsing Binaries: Modelling in the new era of ultra-high precision photometry

    OpenAIRE

    Pavlovski, K.; Bloemen, S.; Degroote, P.; Conroy, K.; Hambleton, Kelly; Giammarco, J.M.; Pablo, H.; Prša, A.; Tkachenko, A.; Torres, G.

    2013-01-01

    Recent ultra-high precision observations of eclipsing binaries, especially data acquired by the Kepler satellite, have made accurate light curve modelling increasingly challenging but also more rewarding. In this contribution, we discuss low-amplitude signals in light curves that can now be used to derive physical information about eclipsing binaries but that were unaccessible before the Kepler era. A notable example is the detection of Doppler beaming, which leads to an increase in flux when...

  13. Evaluating strength at ultra-high temperatures-Methods and results

    International Nuclear Information System (INIS)

    Voelkl, Rainer; Fischer, Bernd; Beschliesser, Manuel; Glatzel, Uwe

    2008-01-01

    Proprietary equipment for mechanical testing at ultra-high temperatures by ohmic heating is outlined. Strain is measured with a video extensometer with an accuracy of up to Δε-bar∼±0.00025%. Stability and accuracy of the test system are evaluated on Pt- and refractory alloys. These specially designed and built test facilities are compared to commercially available high-vacuum test chambers with tungsten heater

  14. The lateral characteristics of several ultra-high energy photon and hadron families

    International Nuclear Information System (INIS)

    Buja, Z.; Gladysz, E.; Mazurkiewicz, J.; Mikocki, S.; Szarska, M.; Zawiejski, L.

    1980-01-01

    In a thick lead X-ray film emulsion chamber of the Experiment Pamir, 8 ultra-high energy photon and hadron families were detected. They are considered to be almost ''pure'' families. The compound lateral characteristics for photon families indicate an existence of two groups of particles which have different average transverse momenta. A quite well visible azimuthal asymmetry in the number and transverse momenta values of produced particles is observed. (author)

  15. Point source search techniques in ultra high energy gamma ray astronomy

    International Nuclear Information System (INIS)

    Alexandreas, D.E.; Biller, S.; Dion, G.M.; Lu, X.Q.; Yodh, G.B.; Berley, D.; Goodman, J.A.; Haines, T.J.; Hoffman, C.M.; Horch, E.; Sinnis, C.; Zhang, W.

    1993-01-01

    Searches for point astrophysical sources of ultra high energy (UHE) gamma rays are plagued by large numbers of background events from isotropic cosmic rays. Some of the methods that have been used to estimate the expected number of background events coming from the direction of a possible source are found to contain biases. Search techniques that avoid this problem are described. There is also a discussion of how to optimize the sensitivity of a search to emission from a point source. (orig.)

  16. Modelling of radiation losses for ion acceleration at ultra-high laser intensities

    Directory of Open Access Journals (Sweden)

    Capdessus Remi

    2013-11-01

    Full Text Available Radiation losses of charged particles can become important in ultra high intensity laser plasma interaction. This process is described by the radiation back reaction term in the electron equation of motion. This term is implemented in the relativistic particle-in-cell code by using a renormalized Lorentz-Abraham-Dirac model. In the hole boring regime case of laser ion acceleration it is shown that radiation losses results in a decrease of the piston velocity.

  17. Molecular characterization of non-thymic lymphomas in mice exposed to continuous low-dose-rate g-ray irradiation

    International Nuclear Information System (INIS)

    Takabatake, T.; Fujikawa, K.; Nakamura, S.; Tanaka, S.; Tanaka, I.; Tanaka-Braga III, I.; Sunaga, Y.; Ichinoche, K.; Sato, F.; Tanaka, K.; Matsumoto, T.

    2004-01-01

    To investigate the effects of continuous low-dose-rate irradiation on life span and neoplasm incidence, SPE B6C3 F1 mice were irradiated with 137Cs-ray at dose-rates of 20, 1 and 0.05 mGy/day with accumulated doses equivalent to 8000, 40 and 20 mGy, respectively. Examination of a total of 3,000 irradiated and 1,000 non-irradiated control mice showed that the life spans of the both sexes irradiated at 20 mGy/day, respectively. Examination of a total of 3,000 irradiated and 1,000 non-irradiated control mice showed that the life spans of the both sexes irradiated at 20 mGy/day were significantly shorter than that of the non-irradiated group. No significant difference in the cause of death and mortality rates was found between the groups. However, non-thymic lymphomas, the most common lethal neoplasm, showed a tendency to develop at an earlier age in mice irradiated with 20 mGy/day, regardless of sex. to obtain clues on the molecular mechanisms underlying the earlier development of non-thymic lymphomas in 20 mGy/day irradiated group, detailed molecular characterizations of non-thymic lymphomas with respect to B-cell or T-cell origin was done by detecting rearrangements in immunoglobulin heavy gene and in T-cell receptor b-and g chain genes by Southem hybridization method. to determine whether the early development of non-thymic lymphomas in 20 mGy/day irradiated group is associated wi the any recurrent chromosomal imbalance such as deletions and amplifications, the genome-wide scanning is also currently in progress by both LOH and array CGH methods. Present data obtained by LOH method show that deletions in parts of chromosomes 11 and 12 were more frequent than in chromosomes 2, 4 and 14 in both the non-irradiated control and 20 mGy/day irradiated groups. this work is supported by grants from Aomori Prefecture, Japan. (Author)

  18. Arc Shape Characteristics with Ultra-High-Frequency Pulsed Arc Welding

    Directory of Open Access Journals (Sweden)

    Mingxuan Yang

    2017-01-01

    Full Text Available Arc plasma possesses a constriction phenomenon with a pulsed current. The constriction is created by the Lorentz force, the radial electromagnetic force during arc welding, which determines the energy distribution of the arc plasma. Welding experiments were carried out with ultra-high-frequency pulsed arc welding (UHFP-AW. Ultra-high-speed camera observations were produced for arc surveillance. Hue-saturation-intensity (HSI image analysis was used to distinguish the regions of the arc plasma that represented the heat energy distribution. The measurement of arc regions indicated that, with an ultra-high-frequency pulsed arc, the constriction was not only within the decreased arc geometry, but also within the constricted arc core region. This can be checked by the ratio of the core region to the total area. The arc core region expanded significantly at 40 kHz at 60 A. A current level of 80 A caused a decrease in the total region of the arc. Meanwhile, the ratio of the core region to the total increased. It can be concluded that arc constriction depends on the increased area of the core region with the pulsed current (>20 kHz.

  19. A Manganin Thin Film Ultra-High Pressure Sensor for Microscale Detonation Pressure Measurement

    Directory of Open Access Journals (Sweden)

    Guodong Zhang

    2018-03-01

    Full Text Available With the development of energetic materials (EMs and microelectromechanical systems (MEMS initiating explosive devices, the measurement of detonation pressure generated by EMs in the microscale has become a pressing need. This paper develops a manganin thin film ultra-high pressure sensor based on MEMS technology for measuring the output pressure from micro-detonator. A reliable coefficient is proposed for designing the sensor’s sensitive element better. The sensor employs sandwich structure: the substrate uses a 0.5 mm thick alumina ceramic, the manganin sensitive element with a size of 0.2 mm × 0.1 mm × 2 μm and copper electrodes of 2 μm thick are sputtered sequentially on the substrate, and a 25 μm thick insulating layer of polyimide is wrapped on the sensitive element. The static test shows that the piezoresistive coefficient of manganin thin film is 0.0125 GPa−1. The dynamic experiment indicates that the detonation pressure of micro-detonator is 12.66 GPa, and the response time of the sensor is 37 ns. In a word, the sensor developed in this study is suitable for measuring ultra-high pressure in microscale and has a shorter response time than that of foil-like manganin gauges. Simultaneously, this study could be beneficial to research on ultra-high-pressure sensors with smaller size.

  20. Simulation of press-forming for automobile part using ultra high tension steel

    Directory of Open Access Journals (Sweden)

    Tanabe I.

    2012-08-01

    Full Text Available In recent years, ultra high tension steel has gradually been used in the automobile industry. The development of press-forming technology is now essential by reason of its high productivity and high product quality. In this study, tensile tests were performed with a view to understanding the material properties. Press-forming tests were then carried out with regard to the behaviors of spring back and deep-drawability, and manufacturing a real product. The ultra high tension steel used in the experiments had a thickness of 1 mm and a tensile strength of 1000 MPa. Finally, simulations of spring back, deep-drawability and manufacturing a real product in ultra high tension steel were conducted and evaluated in order to calculate the optimum-press-forming conditions and the optimum shape of the die. FEM with non-linear and dynamic analysis using Euler-Lagrange’s element was used for the simulations. It is concluded from the results that (1 the simulations conformed to the results of the experiments (2 the simulations proved very effective for calculating the optimum press conditions and die shape.

  1. Changes in molecular structure and properties of irradiated polymers of different compositions - ESR and NMR study

    International Nuclear Information System (INIS)

    Carswell-Pomerantz, T.; Babanalbandi, A.; Dong, L.; Hill, D.J.T.; Perera, M.C.S.; Pomery, P.J.; Saadat, G.; Whittaker, A.K.

    1999-01-01

    Investigations of molecular structural changes in polymers during exposure to high energy radiation is the long term interest of the Polymer Materials and Radiation Group at the University of Queensland. Recently, the group had looked at a range of polymers including natural and synthetic rubbers, methacrylates and polyesters. The objective of the work has been to investigate the relationships between polymer structure and sensitivity towards high energy radiation, including gamma radiation. This report will focus on the Electron Spin Resonance (ESR) and Nuclear Magnetic Resonance (NMR) studies of the effects of gamma irradiation on these polymers. Other methods such as Gas Chromatography (GC), Gel Permeation Chromatography (GPC), Fourier Transformed Infra Red (FTIR), Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TGA) and Dynamic Mechanical Analysis (DMA) have also been used as these methods combine with ESR and NMR, to provide a more complete picture of the mechanism of the structural changes. (author)

  2. Molecular dynamics simulations of irradiation cascades in alpha-zirconium under macroscopic strain

    Energy Technology Data Exchange (ETDEWEB)

    Di, Sali [Department of Mechanical and Materials Engineering, Queen’s University, Kingston, ON, Canada K7L 3N6 (Canada); Yao, Zhongwen, E-mail: yaoz@me.queensu.ca [Department of Mechanical and Materials Engineering, Queen’s University, Kingston, ON, Canada K7L 3N6 (Canada); Daymond, Mark R. [Department of Mechanical and Materials Engineering, Queen’s University, Kingston, ON, Canada K7L 3N6 (Canada); Gao, Fei [Pacific Northwest National Laboratory, Richland, WA 99352 (United States)

    2013-05-15

    Numerous computer simulation studies have been performed on the radiation damage of zirconium. In contrast to most of the work in the literature which has focused on the effects of temperature and recoil energy on defect production and defect clustering, we have developed a computational model to consider the influence of elastic strain field on the formation of defects and their clusters, as strain is commonly present in a real reactor environment. In this work, irradiation induced displacement cascades in alpha-zirconium experiencing a macroscopic strain have been studied by molecular dynamics (MD) simulations using a many-body interatomic potential. The external strain mainly affects the size of defect clusters rather than the total number of defects. The sizes of interstitial and vacancy clusters respond differently to the external strain conditions.

  3. Molecular Dynamics Simulation of Damage to Coiled Carbon Nanotubes under C Ion Irradiation

    International Nuclear Information System (INIS)

    Zhou Bin; Zhang Wei; Gong Wen-Bin; Wang Song; Ren Cui-Lan; Wang Cheng-Bin; Zhu Zhi-Yuan; Huai Ping

    2013-01-01

    The stability of coiled carbon nanotubes under C ion irradiation is investigated by molecular dynamics simulations. The defect statistics shows that small curvature coiled carbon nanotubes have better radiation tolerance than normal straight carbon nanotubes. To understand the effect of the curvature on defect production, the threshold displacement energies for the upper and lower walls, as well as those for the side parts, are calculated. The results show that the lower wall has better radiation tolerance than the upper wall. For the upper wall, a small increase in the curvature of nanotube axis gives rise to an increase in the radiation tolerance and then a decrease with the curvature becomes larger. However, for the lower wall, as the curvature of the nanotube axis increases, the radiation tolerance increases as the bonds compressed slightly in our simulation

  4. Study of bond-energy variations in molecular systems under irradiation; Etude de la variation de l'energie de liaison dans les systemes moleculaires irradies

    Energy Technology Data Exchange (ETDEWEB)

    Naudet, G; Passe, S [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1968-07-01

    On the basis of experimental results selected from publications, the evolution of the bond energy of a molecular system under irradiation - leading to a more or less bound state - is studied. This variation of bond energy is then compared to the total bond energy of the initial system and to the energy absorbed in the system during the irradiation. This is done as a function of the nature of molecular system and the radiation spectrum and intensity. Our working method will first be explained, and the results obtained will then be given. (authors) [French] A l'aide de resultats experimentaux, selectionnes dans les publications, nous etudions l'evolution de l'energie de liaison d'un systeme moleculaire sous irradiation (evolution vers un etat plus ou moins lie), et nous comparons cette variation d'energie de liaison a l'energie totale de liaison du systeme initial et a l'energie absorbee dans le systeme au cours de l'irradiation. Ceci est fait en fonction de la nature du systeme moleculaire ainsi que du spectre et de l'intensite du rayonnement. Nous exposons d'abord notre methode de travail, puis les resultats obtenus. (auteurs)

  5. Immunomodulatory Properties and Molecular Effects in Inflammatory Diseases of Low-Dose X-Irradiation

    International Nuclear Information System (INIS)

    Rödel, Franz; Frey, Benjamin; Manda, Katrin; Hildebrandt, Guido; Hehlgans, Stephanie; Keilholz, Ludwig; Seegenschmiedt, M. Heinrich; Gaipl, Udo S.; Rödel, Claus

    2012-01-01

    Inflammatory diseases are the result of complex and pathologically unbalanced multicellular interactions. For decades, low-dose X-irradiation therapy (LD-RT) has been clinically documented to exert an anti-inflammatory effect on benign diseases and chronic degenerative disorders. By contrast, experimental studies to confirm the effectiveness and to reveal underlying cellular and molecular mechanisms are still at their early stages. During the last decade, however, the modulation of a multitude of immunological processes by LD-RT has been explored in vitro and in vivo. These include leukocyte/endothelial cell adhesion, adhesion molecule and cytokine/chemokine expression, apoptosis induction, and mononuclear/polymorphonuclear cell metabolism and activity. Interestingly, these mechanisms display comparable dose dependences and dose-effect relationships with a maximum effect in the range between 0.3 and 0.7 Gy, already empirically identified to be most effective in the clinical routine. This review summarizes data and models exploring the mechanisms underlying the immunomodulatory properties of LD-RT that may serve as a prerequisite for further systematic analyses to optimize low-dose irradiation procedures in future clinical practice.

  6. Immunomodulatory Properties and Molecular Effects in Inflammatory Diseases of Low-Dose X-Irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Rödel, Franz [Department of Radiotherapy and Oncology, University Hospital of Frankfurt, Johann Wolfgang-Goethe Universität, Frankfurt am Main (Germany); Frey, Benjamin [Department of Radiation Oncology, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen (Germany); Manda, Katrin; Hildebrandt, Guido [Department of Radiotherapy and Radiation Oncology, University of Rostock, Rostock (Germany); Hehlgans, Stephanie [Department of Radiotherapy and Oncology, University Hospital of Frankfurt, Johann Wolfgang-Goethe Universität, Frankfurt am Main (Germany); Keilholz, Ludwig [Department of Radiotherapy, Clinical Center Bayreuth, Bayreuth (Germany); Seegenschmiedt, M. Heinrich [Strahlenzentrum Hamburg Medizinisches Versorgungszentrum, Hamburg (Germany); Gaipl, Udo S. [Department of Radiation Oncology, University Hospital Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen (Germany); Rödel, Claus, E-mail: franz.roedel@kgu.de [Department of Radiotherapy and Oncology, University Hospital of Frankfurt, Johann Wolfgang-Goethe Universität, Frankfurt am Main (Germany)

    2012-09-25

    Inflammatory diseases are the result of complex and pathologically unbalanced multicellular interactions. For decades, low-dose X-irradiation therapy (LD-RT) has been clinically documented to exert an anti-inflammatory effect on benign diseases and chronic degenerative disorders. By contrast, experimental studies to confirm the effectiveness and to reveal underlying cellular and molecular mechanisms are still at their early stages. During the last decade, however, the modulation of a multitude of immunological processes by LD-RT has been explored in vitro and in vivo. These include leukocyte/endothelial cell adhesion, adhesion molecule and cytokine/chemokine expression, apoptosis induction, and mononuclear/polymorphonuclear cell metabolism and activity. Interestingly, these mechanisms display comparable dose dependences and dose-effect relationships with a maximum effect in the range between 0.3 and 0.7 Gy, already empirically identified to be most effective in the clinical routine. This review summarizes data and models exploring the mechanisms underlying the immunomodulatory properties of LD-RT that may serve as a prerequisite for further systematic analyses to optimize low-dose irradiation procedures in future clinical practice.

  7. Ex vivo irradiation of human blood to determine DNA damage using molecular techniques

    International Nuclear Information System (INIS)

    Montes, Angel; Agapito, Juan

    2014-01-01

    Biological dosimetry is the assessment of absorbed dose in individuals exposed to ionizing radiation from blood samples based on the radiation induced damage in cellular DNA. The aim of this study was to determine the damage in the DNA through the assessment of an experimental ex vivo assay using irradiated samples of human blood cells. For this purpose, blood samples were irradiated at low doses (<100 mGy) considering the following parameters: blood volume (3mL), temperature (37 °C) and incubation time (0.5, 2, 4, 8 and 24 h). Dose values were: 0, 12.5, 25 and 50 mGy using Cesium -137 gamma rays at 662 keV and a dose rate of 38.46 mGy/h. The qualitative damage in the genomic DNA was determined using agarose gel electrophoresis and polymerase chain reaction (PCR) for the p53 gene in a sequence of 133 pb of exon 7, related to the protein that acts in the cell repair process. The results of the qualitative analysis showed no degradation of genomic DNA; also an increase in the DNA concentration was observed up to the fourth hour of incubation, finding maximum values for all doses in the two samples. As a conclusion, the effects of ionizing radiation at doses used in this experiment do not generate a detectable damage, by means of molecular techniques such as those used in the present study. (authors).

  8. Investigation of Plasma Eects in Ultra High Molecular Weight Polyethylene (UHMWPE) Cords

    DEFF Research Database (Denmark)

    Teodoru, Steluta; Kusano, Yukihiro; Rozlosnik, Noemi

    modication for improved wetting and/or adhesion with other polymeric materials. Atmospheric pressure plasma treatment is promising for this purpose due to its environmental compatibility, high treatment eects without aecting the textural characteristics of the bulk material, its applicability to a variety...... of shapes, and easy up-scaling and construction of in-line production processes. An atmospheric pressure dielectric barrier discharge (DBD) plasma is used to study surface modication eect on UHMWPE cords, operated at a frequency of ca. 40 kHz in He, He/O2, O2 and N2 gases. The cords were continuously...

  9. Continuous Plasma Treatment of Ultra-High-Molecular-Weight Polyethylene (UHMWPE) Fibres for Adhesion Improvement

    DEFF Research Database (Denmark)

    Teodoru, Steluta; Kusano, Yukihiro; Rozlosnik, Noemi

    2009-01-01

    A dielectric barrier discharge in Ar, He, He/O2, N2 or O2 at atmospheric pressure was used for the continuous plasma treatment of UHMWPE fibres. The influence of the input power of the discharge and the gas flow rate on surface modification is studied with the aim of adhesion improvement. Surface...

  10. Modeling Ballistic Response of Ultra-High-Molecular-Weight Polyethylene (UHMWPE)

    Science.gov (United States)

    2016-07-01

    in high-speed penetration problems , the material would fail and erode, and the regular contact algorithm cannot update the contact surfaces...High velocity impact and armour design. Express Polymer Letters. 2011;5(3):262–272. 14. Chocron S, King N, Walker JD, Heisserer U, Werff H

  11. Surface modification of ultra-high molecular weight polyethylene (UHMWPE) by argon plasma

    International Nuclear Information System (INIS)

    Liu Hengjun; Pei Yanan; Xie Dong; Deng Xingrui; Leng, Y.X.; Jin Yong; Huang Nan

    2010-01-01

    In this work, argon (Ar) plasma generated by microwave electron cyclotron resonance (MWECR) has been used to modify the UHMWPE in order to increase the wear resistance. The results showed that the wettability, anti-scratch and wear resistance of UHMWPE treated by the Ar plasma had been improved, comparing with native UHMWPE. The FTIR and XPS spectra indicated the improvement of wettability should come from the oxygen based functional groups generated on the surface of UHMWPE. The improvement of anti-scratch and wear resistance may come from the enhancement of crosslinking of UHMWPE by Ar plasma treatment.

  12. The physical and chemical properties of plasma treated ultra-high-molecular-weight polyethylene fibers

    DEFF Research Database (Denmark)

    Kusano, Yukihiro; Teodoru, Steluta; Hansen, Charles M.

    2011-01-01

    A uniform and smooth transfer of stresses across the polymer matrix/fiber interface is enhanced when adhesion between the matrix and fiber surface is optimized. In the absence of covalent bonds matching the Hansen solubility (cohesion) parameters (HSP) of the fiber surface with the HSP of a matrix...... at 18.0, 1.2, and 1.4, all in MPa½. The dispersion parameter has been lowered somewhat by the plasma treatment, while the polar and hydrogen bonding parameters are much higher. The HSP methodology predicts enhanced adhesion is possible by skillful use of anhydride and nitrile functional groups in matrix...

  13. Development of Thin-film Dye-sensitized Photoactive Materials on Ultra High Molecular Weight Polyethylene

    Science.gov (United States)

    2012-04-01

    although it is used as a base in most paints due to its light scattering ability. In general, a pure anatase TiO2 nanostructure is preferred over...solution, 0.1%, 0.5%, and 1% of pristine graphene was added to each solution. The solution was then stirred for 15 min and then sonicated for 20 min

  14. Next-generation technologies for spatial proteomics: Integrating ultra-high speed MALDI-TOF and high mass resolution MALDI FTICR imaging mass spectrometry for protein analysis.

    Science.gov (United States)

    Spraggins, Jeffrey M; Rizzo, David G; Moore, Jessica L; Noto, Michael J; Skaar, Eric P; Caprioli, Richard M

    2016-06-01

    MALDI imaging mass spectrometry is a powerful analytical tool enabling the visualization of biomolecules in tissue. However, there are unique challenges associated with protein imaging experiments including the need for higher spatial resolution capabilities, improved image acquisition rates, and better molecular specificity. Here we demonstrate the capabilities of ultra-high speed MALDI-TOF and high mass resolution MALDI FTICR IMS platforms as they relate to these challenges. High spatial resolution MALDI-TOF protein images of rat brain tissue and cystic fibrosis lung tissue were acquired at image acquisition rates >25 pixels/s. Structures as small as 50 μm were spatially resolved and proteins associated with host immune response were observed in cystic fibrosis lung tissue. Ultra-high speed MALDI-TOF enables unique applications including megapixel molecular imaging as demonstrated for lipid analysis of cystic fibrosis lung tissue. Additionally, imaging experiments using MALDI FTICR IMS were shown to produce data with high mass accuracy (z 5000) for proteins up to ∼20 kDa. Analysis of clear cell renal cell carcinoma using MALDI FTICR IMS identified specific proteins localized to healthy tissue regions, within the tumor, and also in areas of increased vascularization around the tumor. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. Comparison of ultra-high performance supercritical fluid chromatography and ultra-high performance liquid chromatography for the separation of spirostanol saponins.

    Science.gov (United States)

    Zhu, Ling-Ling; Zhao, Yang; Xu, Yong-Wei; Sun, Qing-Long; Sun, Xin-Guang; Kang, Li-Ping; Yan, Ren-Yi; Zhang, Jie; Liu, Chao; Ma, Bai-Ping

    2016-02-20

    Spirostanol saponins are important active components of some herb medicines, and their isolation and purification are crucial for the research and development of traditional Chinese medicines. We aimed to compare the separation of spirostanol saponins by ultra-high performance supercritical fluid chromatography (UHPSFC) and ultra-high performance liquid chromatography (UHPLC). Four groups of spirostanol saponins were separated respectively by UHPSFC and UHPLC. After optimization, UHPSFC was performed with a HSS C18 SB column or a Diol column and with methanol as the co-solvent. A BEH C18 column and mobile phase containing water (with 0.1% formic acid) and acetonitrile were used in UHPLC. We found that UHPSFC could be performed automatically and quickly. It is effective in separating the spirostanol saponins which share the same aglycone and vary in sugar chains, and is very sensitive to the number and the position of hydroxyl groups in aglycones. However, the resolution of spirostanol saponins with different aglycones and the same sugar moiety by UHPSFC was not ideal and could be resolved by UHPLC instead. UHPLC is good at differentiating the variation in aglycones, and is influenced by double bonds in aglycones. Therefore, UHPLC and UHPSFC are complementary in separating spirostanol saponins. Considering the naturally produced spirostanol saponins in herb medicines are different both in aglycones and in sugar chains, a better separation can be achieved by combination of UHPLC and UHPSFC. UHPSFC is a powerful technique for improving the resolution when UHPLC cannot resolve a mixture of spirostanol saponins and vice versa. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. Ultra-high performance fiber-reinforced concrete (UHPFRC) for infrastructure rehabilitation Volume II : behavior of ultra-high strength concrete bridge deck panels compared to conventional stay-in-place deck panels

    Science.gov (United States)

    2017-08-01

    The remarkable features of ultra-high performance concrete (UHPC) have been reported. Its application in bridge construction has been an active research area in recent years, attributed to its higher compressive strength, higher ductility and reduced...

  17. Orientation and properties of the blends on high-molecular mass polyacrylonitrile with trihydroxyethylenedimethacrylate under electron irradiation

    International Nuclear Information System (INIS)

    Lomonosova, N.V.

    1998-01-01

    Molecular orientation of the drawn blends of high- molecular-mass poly(acrylonitrile) containing 5-50 wt % of trihydroxyethylenedimethacrylate and a change in the orientation of the drawn samples upon irradiation with accelerated electrons was studied by methods of birefringence, isometric heating, and IR dichroism. The degree of orientation of the unirradiated blends containing certain amounts of oligomer exceed that of the individual polymer. In the region of large drawing ratios, the differential degree of orientation of the polymer matrix is not affected by the irradiation, while the orientation of the oligomer component increase. High values of the strength (600-730 MPa) and the modulus (18-22 GPa) of the compositions are due to the presence of a crystalline skeleton formed by unfolded chains of the polymer matrix stabilized by the electron irradiation induced cross-linking

  18. Ultra High Temperature and Multifunctional Ceramic Matrix Composite – Coating Systems for Light-Weight Space and Aero Systems

    Data.gov (United States)

    National Aeronautics and Space Administration — Revolutionary ultra-high temperature, high mechanical loading capable, oxidation resistant, durable ceramic coatings and light-weight fiber-reinforced Ceramic Matrix...

  19. Pre-pulse inhibition and striatal dopamine in subjects at an ultra-high risk for psychosis

    NARCIS (Netherlands)

    de Koning, Mariken B.; Bloemen, Oswald J. N.; van Duin, Esther D. A.; Booij, Jan; Abel, Kathryn M.; de Haan, Lieuwe; Linszen, Don H.; van Amelsvoort, Thérèse A. M. J.

    2014-01-01

    Reduced prepulse inhibition (PPI) of the acoustic startle response is thought to represent a robust biomarker in schizophrenia. Reduced PPI has been demonstrated in subjects at ultra high risk (UHR) for developing psychosis. Imaging studies report disruption of striatal dopaminergic

  20. Metabolite profiling and quantification of phytochemicals in potato extracts using ultra-high-performance liquid chromatography-mass spectrometry.

    Science.gov (United States)

    Chong, Esther Swee Lan; McGhie, Tony K; Heyes, Julian A; Stowell, Kathryn M

    2013-12-01

    Potatoes contain a diverse range of phytochemicals which have been suggested to have health benefits. Metabolite profiling and quantification were conducted on plant extracts made from a white potato cultivar and 'Urenika', a purple potato cultivar traditionally consumed by New Zealand Maori. There is limited published information regarding the metabolite profile of Solanum tuberosum cultivar 'Urenika'. Using ultra-high- performance liquid chromatography-mass spectrometry (UHPLC-MS), a total of 31 compounds were identified and quantified in the potato extracts. The majority of the compounds were identified for the first time in 'Urenika'. These compounds include several types of anthocyanins, hydroxycinnamic acid (HCA) derivatives, and hydroxycinnamic amides (HCAA). Six classes of compounds, namely organic acids, amino acids, HCA, HCAA, flavonols and glycoalkaloids, were present in both extracts but quantities varied between the two extracts. The unknown plant metabolites in both potato extracts were assigned with molecular formulae and identified with high confidence. Quantification of the metabolites was achieved using a number of appropriate standards. High-resolution mass spectrometry data critical for accurate identification of unknown phytochemicals were achieved and could be added to potato or plant metabolomic database. © 2013 Society of Chemical Industry.

  1. Metabolite Analysis of Toosendanin by an Ultra-High Performance Liquid Chromatography-Quadrupole-Time of Flight Mass Spectrometry Technique

    Directory of Open Access Journals (Sweden)

    Na Li

    2013-09-01

    Full Text Available Toosendanin is the major bioactive component of Melia toosendan Sieb. et Zucc., which is traditionally used for treatment of abdominal pain and as an insecticide. Previous studies reported that toosendanin possesses hepatotoxicity, but the mechanism remains unknown. Its bioavailability in rats is low, which indicates the hepatotoxicity might be induced by its metabolites. In this connection, in the current study, we examined the metabolites obtained by incubating toosendanin with human live microsomes, and then six of these metabolites (M1–M6 were identified for the first time by ultra-high performance liquid chromatography-quadrupole-time of flight mass spectrometry (UHPLC-Q-TOF/MS. Further analysis on the MS spectra showed M1, M2, and M3 are oxidative products and M6 is a dehydrogenation product, while M4 and M5 are oxidative and dehydrogenation products of toosendanin. Moreover, their possible structures were deduced from the MS/MS spectral features. Quantitative analysis demonstrated that M1-M5 levels rapidly increased and reached a plateau at 30 min, while M6 rapidly reached a maximal level at 20 min and then decreased slowly afterwards. These findings have provided valuable data not only for understanding the metabolic fate of toosendanin in liver microsomes, but also for elucidating the possible molecular mechanism of its hepatotoxicity.

  2. Oligomers, organosulfates, and nitrooxy organosulfates in rainwater identified by ultra-high resolution electrospray ionization FT-ICR mass spectrometry

    Directory of Open Access Journals (Sweden)

    K. E. Altieri

    2009-04-01

    Full Text Available Wet deposition is an important removal mechanism for atmospheric organic matter, and a potentially important input for receiving ecosystems, yet less than 50% of rainwater organic matter is considered chemically characterized. Precipitation samples collected in New Jersey, USA, were analyzed by negative ion ultra-high resolution electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS. Elemental compositions of 552 unique molecular species were determined in the mass range 50–500 Da in the rainwater. Four main groups of organic compounds were identified: compounds containing carbon, hydrogen, and oxygen (CHO only, sulfur (S containing CHOS compounds, nitrogen (N containing CHON compounds, and S- and N- containing CHONS compounds. Organic acids commonly identified in precipitation were detected in the rainwater. Within the four main groups of compounds detected in the rainwater, oligomers, organosulfates, and nitrooxy-organosulfates were assigned based on elemental formula comparisons. The majority of the compounds identified are products of atmospheric reactions and are known contributors to secondary organic aerosol (SOA formed from gas phase, aerosol phase, and in-cloud reactions in the atmosphere. It is suggested that the large uncharacterized component of SOA is the main contributor to the large uncharacterized component of rainwater organic matter.

  3. Effect of γ-ray irradiation on the structure and melt fluidity of UHMWPE

    International Nuclear Information System (INIS)

    Liu Pengbo; Fan Ping; Xu Wen; Wang Kai

    2005-01-01

    Ultra-high molecular weight polyethylene (UHMWPE) was irradiated in air by 60 Co γ-rays. The effect of γ-ray irradiation on the structure and properties of UHMWPE was studied by FTIR, intrinsic viscosity measurement, melt flow rate (MFR) measurement and mechanical property test. The experimental results show that oxygen-containing groups (mainly carbonyl group) were introduced on the molecular chain of UHMWPE during the irradiation, which caused degradation of UHMWPE. Molecular weight of UHMWPE decreased and melt flow rate increased obviously. Compared with the virgin UHMWPE, MFR of the 100 kGy-irradiated UHMWPE increased from virtually nothing to 4.8 g/10 min. Tensile yield strength and elongation at break of the irradiated UHMWPE samples were improved, whereas notched lzod impact strength of the samples decreased. Compared with the virgin UHMWPE, elongation at break of the UHMWPE samples irradiated to 100 kGy increased from 367% to 801%, and their notched lzod impact strength decreased to 576 J/m from over 1000. (authors)

  4. Ultra-high throughput real-time instruments for capturing fast signals and rare events

    Science.gov (United States)

    Buckley, Brandon Walter

    Wide-band signals play important roles in the most exciting areas of science, engineering, and medicine. To keep up with the demands of exploding internet traffic, modern data centers and communication networks are employing increasingly faster data rates. Wide-band techniques such as pulsed radar jamming and spread spectrum frequency hopping are used on the battlefield to wrestle control of the electromagnetic spectrum. Neurons communicate with each other using transient action potentials that last for only milliseconds at a time. And in the search for rare cells, biologists flow large populations of cells single file down microfluidic channels, interrogating them one-by-one, tens of thousands of times per second. Studying and enabling such high-speed phenomena pose enormous technical challenges. For one, parasitic capacitance inherent in analog electrical components limits their response time. Additionally, converting these fast analog signals to the digital domain requires enormous sampling speeds, which can lead to significant jitter and distortion. State-of-the-art imaging technologies, essential for studying biological dynamics and cells in flow, are limited in speed and sensitivity by finite charge transfer and read rates, and by the small numbers of photo-electrons accumulated in short integration times. And finally, ultra-high throughput real-time digital processing is required at the backend to analyze the streaming data. In this thesis, I discuss my work in developing real-time instruments, employing ultrafast optical techniques, which overcome some of these obstacles. In particular, I use broadband dispersive optics to slow down fast signals to speeds accessible to high-bit depth digitizers and signal processors. I also apply telecommunication multiplexing techniques to boost the speeds of confocal fluorescence microscopy. The photonic time stretcher (TiSER) uses dispersive Fourier transformation to slow down analog signals before digitization and

  5. Kernel based methods for accelerated failure time model with ultra-high dimensional data

    Directory of Open Access Journals (Sweden)

    Jiang Feng

    2010-12-01

    Full Text Available Abstract Background Most genomic data have ultra-high dimensions with more than 10,000 genes (probes. Regularization methods with L1 and Lp penalty have been extensively studied in survival analysis with high-dimensional genomic data. However, when the sample size n ≪ m (the number of genes, directly identifying a small subset of genes from ultra-high (m > 10, 000 dimensional data is time-consuming and not computationally efficient. In current microarray analysis, what people really do is select a couple of thousands (or hundreds of genes using univariate analysis or statistical tests, and then apply the LASSO-type penalty to further reduce the number of disease associated genes. This two-step procedure may introduce bias and inaccuracy and lead us to miss biologically important genes. Results The accelerated failure time (AFT model is a linear regression model and a useful alternative to the Cox model for survival analysis. In this paper, we propose a nonlinear kernel based AFT model and an efficient variable selection method with adaptive kernel ridge regression. Our proposed variable selection method is based on the kernel matrix and dual problem with a much smaller n × n matrix. It is very efficient when the number of unknown variables (genes is much larger than the number of samples. Moreover, the primal variables are explicitly updated and the sparsity in the solution is exploited. Conclusions Our proposed methods can simultaneously identify survival associated prognostic factors and predict survival outcomes with ultra-high dimensional genomic data. We have demonstrated the performance of our methods with both simulation and real data. The proposed method performs superbly with limited computational studies.

  6. Ultra high spatial and temporal resolution breast imaging at 7T.

    Science.gov (United States)

    van de Bank, B L; Voogt, I J; Italiaander, M; Stehouwer, B L; Boer, V O; Luijten, P R; Klomp, D W J

    2013-04-01

    There is a need to obtain higher specificity in the detection of breast lesions using MRI. To address this need, Dynamic Contrast-Enhanced (DCE) MRI has been combined with other structural and functional MRI techniques. Unfortunately, owing to time constraints structural images at ultra-high spatial resolution can generally not be obtained during contrast uptake, whereas the relatively low spatial resolution of functional imaging (e.g. diffusion and perfusion) limits the detection of small lesions. To be able to increase spatial as well as temporal resolution simultaneously, the sensitivity of MR detection needs to increase as well as the ability to effectively accelerate the acquisition. The required gain in signal-to-noise ratio (SNR) can be obtained at 7T, whereas acceleration can be obtained with high-density receiver coil arrays. In this case, morphological imaging can be merged with DCE-MRI, and other functional techniques can be obtained at higher spatial resolution, and with less distortion [e.g. Diffusion Weighted Imaging (DWI)]. To test the feasibility of this concept, we developed a unilateral breast coil for 7T. It comprises a volume optimized dual-channel transmit coil combined with a 30-channel receive array coil. The high density of small coil elements enabled efficient acceleration in any direction to acquire ultra high spatial resolution MRI of close to 0.6 mm isotropic detail within a temporal resolution of 69 s, high spatial resolution MRI of 1.5 mm isotropic within an ultra high temporal resolution of 6.7 s and low distortion DWI at 7T, all validated in phantoms, healthy volunteers and a patient with a lesion in the right breast classified as Breast Imaging Reporting and Data System (BI-RADS) IV. Copyright © 2012 John Wiley & Sons, Ltd.

  7. Recent Ultra High Energy neutrino bounds and multimessenger observations with the Pierre Auger Observatory

    Science.gov (United States)

    Zas, Enrique

    2018-01-01

    The overall picture of the highest energy particles produced in the Universe is changing because of measurements made with the Pierre Auger Observatory. Composition studies of cosmic rays point towards an unexpected mixed composition of intermediate mass nuclei, more isotropic than anticipated, which is reshaping the future of the field and underlining the priority to understand composition at the highest energies. The Observatory is competitive in the search for neutrinos of all flavors above about 100 PeV by looking for very inclined showers produced deep in the atmosphere by neutrinos interacting either in the atmosphere or in the Earth's crust. It covers a large field of view between -85° and 60° declination in equatorial coordinates. Neutrinos are expected because of the existence of ultra high energy cosmic rays. They provide valuable complementary information, their fluxes being sensitive to the primary cosmic ray masses and their directions reflecting the source positions. We report the results of the neutrino search providing competitive bounds to neutrino production and strong constraints to a number of production models including cosmogenic neutrinos due to ultra high energy protons. We also report on two recent contributions of the Observatory to multimessenger studies by searching for correlations of neutrinos both with cosmic rays and with gravitational waves. The correlations of the directions of the highest energy astrophysical neutrinos discovered with IceCube with the highest energy cosmic rays detected with the Auger Observatory and the Telescope Array revealed an excess that is not statistically significant and is being monitored. The targeted search for neutrinos correlated with the discovery of the gravitational wave events GW150914 and GW151226 with advanced LIGO has led to the first bounds on the energy emitted by black hole mergers in Ultra-High Energy Neutrinos.

  8. Design and Fabrication of a Piezoresistive Pressure Sensor for Ultra High Temperature Environment

    International Nuclear Information System (INIS)

    Zhao, L B; Zhao, Y L; Jiang, Z D

    2006-01-01

    In order to solve the pressure measurement problem in the harsh environment, a piezoresistive pressure sensor has been developed, which can be used under high temperature above 200 deg. C and is able to endure instantaneous ultra high temperature (2000deg. C, duration≤2s) impact. Based on the MEMS (Micro Electro-Mechanical System) and integrated circuit technology, the piezoresistive pressure sensor's sensitive element was fabricated and constituted by silicon substrate, a thin buried silicon dioxide layer, four p-type resistors in the measuring circuit layer by boron ion implantation and photolithography, the top SiO2 layer by oxidation, stress matching Si3N4 layer, and a Ti-Pt-Au beam lead layer for connecting p-type resistors by sputtering. In order to decrease the leak-current influence to sensor in high temperature above 200deg. C, the buried SiO2 layer with the thickness 367 nm was fabricated by the SIMOX (Separation by Implantation of Oxygen) technology, which was instead of p-n junction to isolate the upper measuring circuit layer from Si substrate. In order to endure instantaneous ultra high temperature impact, the mechanical structure with cantilever and diaphragm and transmitting beam was designed. By laser welding and high temperature packaging technology, the high temperature piezoresistive pressure sensor was fabricated with range of 120MPa. After the thermal compensation, the sensor's thermal zero drift k 0 and thermal sensitivity drift k s were easy to be less than 3x10 -4 FS/deg. C. The experimental results show that the developed piezoresistive pressure sensor has good performances under high temperature and is able to endure instantaneous ultra high temperature impact, which meets the requirements of modern industry, such as aviation, oil, engine, etc

  9. Recent Ultra High Energy neutrino bounds and multimessenger observations with the Pierre Auger Observatory

    Directory of Open Access Journals (Sweden)

    Zas Enrique

    2017-01-01

    Full Text Available The overall picture of the highest energy particles produced in the Universe is changing because of measurements made with the Pierre Auger Observatory. Composition studies of cosmic rays point towards an unexpected mixed composition of intermediate mass nuclei, more isotropic than anticipated, which is reshaping the future of the field and underlining the priority to understand composition at the highest energies. The Observatory is competitive in the search for neutrinos of all flavors above about 100 PeV by looking for very inclined showers produced deep in the atmosphere by neutrinos interacting either in the atmosphere or in the Earth’s crust. It covers a large field of view between −85◦ and 60◦ declination in equatorial coordinates. Neutrinos are expected because of the existence of ultra high energy cosmic rays. They provide valuable complementary information, their fluxes being sensitive to the primary cosmic ray masses and their directions reflecting the source positions. We report the results of the neutrino search providing competitive bounds to neutrino production and strong constraints to a number of production models including cosmogenic neutrinos due to ultra high energy protons. We also report on two recent contributions of the Observatory to multimessenger studies by searching for correlations of neutrinos both with cosmic rays and with gravitational waves. The correlations of the directions of the highest energy astrophysical neutrinos discovered with IceCube with the highest energy cosmic rays detected with the Auger Observatory and the Telescope Array revealed an excess that is not statistically significant and is being monitored. The targeted search for neutrinos correlated with the discovery of the gravitational wave events GW150914 and GW151226 with advanced LIGO has led to the first bounds on the energy emitted by black hole mergers in Ultra-High Energy Neutrinos.

  10. Ultra-high-speed imaging of the brain by the echo planar technique

    International Nuclear Information System (INIS)

    Worthington, B.S.; Stehling, M.K.; Ordidge, R.J.; Coxon, R.; Howseman, A.M.; Chapman, B.; Turner, R.; Firth, J.L.; Mansfield, P.

    1988-01-01

    Reduced examination time, greater patient tolerance and throughput, and the ability to study vascular and cerebrospinal fluid (CSF) flow phenomena are important advantages of ultra-high-speed brain imaging. The EPI derivatives BEST and MBEST create a complete 128 X 128-pixel image in 64 msec and 128 msec, respectively. In BEST images, T2 weighting is altered by adjusting the echo time, modulus BEST images have intrinsic T2 weighting. Repetition time alterations provide variable T1 weighting in both. Volunteer and patient studies illustrate how selective contrast manipulation allows excellent discrimination between gray and white matter and the brain and the CSF, enabling the demonstration of pathology

  11. Static, Fire and Fatigue Tests of Ultra High-Strength Fibre Reinforced Concrete and Ribbed Bars

    DEFF Research Database (Denmark)

    Hansen, Lars Pilegaard; Heshe, Gert

    2001-01-01

    A new building system has been developed during the last 10 years. This new system consists of a column / slab system with 6 x 6 m distance between the columns. The slabs are precast concrete elements of size 2.9 x 5.9 m connected through joints of ultra high strength fibre reinforced concrete...... - Densit Joint Cast ®. Also the connections between the columns and the slabs are made of this very strong concrete material. The paper describes some of the static tests carried out as well as some fire tests. Further, 2 chapters deal with some fatigue tests of the reinforcing bars as well as some fatigue...

  12. Features of the galactic magnetic field regarding deflections of ultra-high-energy cosmic rays

    Energy Technology Data Exchange (ETDEWEB)

    Wirtz, Marcus; Erdmann, Martin; Mueller, Gero; Urban, Martin [III. Physikalisches Institut A, RWTH Aachen University (Germany)

    2016-07-01

    Most recent models of the galactic magnetic field have been derived from Faraday rotation measurements and imply strong deflections even for ultra-high energy cosmic rays. We investigate the characteristics of the different field parametrizations and point out similarities and interesting features. Among them are extragalactic regions which are invisible for an Earth bound observation and the transition from diffuse to ballistic behaviour in the 1 EeV energy regime. Applying this knowledge to a directional analysis, there are indications for deflection patterns by the galactic magnetic field in cosmic ray arrival directions measured by the Pierre Auger Observatory.

  13. The spheromak as a prototype for ultra-high-field superconducting magnets

    International Nuclear Information System (INIS)

    Furth, H.P.; Jardin, S.C.

    1987-08-01

    In view of current progress in the development of superconductor materials, the ultimate high-field limit of superconducting magnets is likely to be set by mechanical stress problems. Maximum field strength should be attainable by means of approximately force-free magnet windings having favorable ''MHD'' stability properties (so that small winding errors will not grow). Since a low-beta finite-flux-hole spheromak configuration qualifies as a suitable prototype, the theoretical and experimental spheromak research effort of the past decade has served to create a substantial technical basis for the design of ultra-high-field superconducting coils. 11 refs

  14. Performance analysis of InSb based QWFET for ultra high speed applications

    International Nuclear Information System (INIS)

    Subash, T. D.; Gnanasekaran, T.; Divya, C.

    2015-01-01

    An indium antimonide based QWFET (quantum well field effect transistor) with the gate length down to 50 nm has been designed and investigated for the first time for L-band radar applications at 230 GHz. QWFETs are designed at the high performance node of the International Technology Road Map for Semiconductors (ITRS) requirements of drive current (Semiconductor Industry Association 2010). The performance of the device is investigated using the SYNOPSYS CAD (TCAD) software. InSb based QWFET could be a promising device technology for very low power and ultra-high speed performance with 5–10 times low DC power dissipation. (semiconductor devices)

  15. A study of some features of the ultra high vacuum systems for EPIC

    International Nuclear Information System (INIS)

    Elsey, R.J.; Bennett, J.R.J.; Dossett, A.J.

    1977-01-01

    This report covers the experimental work carried out towards the development of the ultra high vacuum for the proposed electron positron storage ring, EPIC. Experiments included outgassing tests on samples of materials and pump-down tests on full scale aluminium vessels. The effect of baking was investigated. The approval of the similar machine PETRA at Hamburg and the subsequent withdrawal of the EPIC proposal in October 1975 curtailed the vacuum work. The experiments reported here are therefore incomplete, but nevertheless proved useful in showing that there should have been no major problems with building the vacuum system for EPIC. (author)

  16. Testing and Modeling Ultra-High Temperature Ceramic (UHTC) Materials For Hypersonic Flight

    Science.gov (United States)

    2011-11-30

    Ridge, D. G. Fletcher, C. O. Asma , O. Chazot, and J. Thömel, “Oxidation of ZrB2-SiC Ultra-High Temperature Ceramic Composites in Dissociated Air...Fletcher, C. O. Asma , “Characterization of ZrB2-SiC Ceramics Tested by Plasma Stream Oxidation,” poster, 32 th International Conference...Fahrenholtz, W.G., Hilmas, G.E., Zhu, S.M., Ridge, J., Fletcher, D.G., Asma , C.O., and Thomel, J., "Oxidation of ZrB2-SiC Ultrahigh-Temperature

  17. Search for continuous and single day emission from ultra-high-energy sources

    International Nuclear Information System (INIS)

    Chen, Mei-Li.

    1993-01-01

    Data from the CYGNUS experiment has been used to search the northern sky for point sources of continuous ultra-high-energy gamma radiation and to examine 51 candidate sources on a daily basis to search for episodic emission. In this paper, we make use of our most recent data to update our previously published results from these searches. The data sample is approximately twice as large as the published data set for continuous emission, and contains an additional year for the daily search. The latest results, up to the time of the conference, will be presented at the meeting

  18. Application of Ultra High Performance Fiber Reinforced Concrete – The Malaysia Perspective

    OpenAIRE

    Voo - Yen Lei; Behzad Nematollahi; Abu Bakar Mohamed Said; Balamurugan A Gopal; Tet Shun Yee

    2012-01-01

    One of the most significant breakthroughs in concrete technology at the end of the 20th century was the development of ultra-high performance fiber reinforced concrete (UHPFRC) with compressive strength and flexure strength beyond 160 MPa and 30 MPa, respectively; remarkable improvement in workability; durability resembled to natural rocks; ductility and toughness comparable to steel. While over the last two decades a tremendous amount of research works have been undertaken by academics and e...

  19. Ultra-high vacuum system of the Brookhaven National Synchrotron Light Source

    International Nuclear Information System (INIS)

    Foerster, C.L.

    1995-01-01

    The rings of the National Synchrotron Light Source (NSLS) have been supplying light to numerous users for approximately a decade and recently a fully conditioned machine vacuum at design currents was obtained. A brief description of the x-ray storage ring, the VUV storage ring and their current supply is given along with some of their features. The ultra-high vacuum system employed for the storage rings and their advantages for the necessary stored beam environments are discussed including, a brief history of time. 15 refs., 2 tabs., 8 figs

  20. Systems and methods for advanced ultra-high-performance InP solar cells

    Science.gov (United States)

    Wanlass, Mark

    2017-03-07

    Systems and Methods for Advanced Ultra-High-Performance InP Solar Cells are provided. In one embodiment, an InP photovoltaic device comprises: a p-n junction absorber layer comprising at least one InP layer; a front surface confinement layer; and a back surface confinement layer; wherein either the front surface confinement layer or the back surface confinement layer forms part of a High-Low (HL) doping architecture; and wherein either the front surface confinement layer or the back surface confinement layer forms part of a heterointerface system architecture.

  1. Ultra-high Q terahertz whispering-gallery modes in a silicon resonator

    Science.gov (United States)

    Vogt, Dominik Walter; Leonhardt, Rainer

    2018-05-01

    We report on the first experimental demonstration of terahertz (THz) whispering-gallery modes (WGMs) with an ultra-high quality factor of 1.5 × 104 at 0.62 THz. The WGMs are observed in a high resistivity float zone silicon spherical resonator coupled to a sub-wavelength silica waveguide. A detailed analysis of the coherent continuous wave THz spectroscopy measurements combined with a numerical model based on Mie-Debye-Aden-Kerker theory allows us to unambiguously identify the observed higher order radial THz WGMs.

  2. Low loss hollow optical-waveguide connection from atmospheric pressure to ultra-high vacuum

    Energy Technology Data Exchange (ETDEWEB)

    Ermolov, A.; Mak, K. F.; Tani, F.; Hölzer, P.; Travers, J. C. [Max Planck Institute for the Science of Light, Günther-Scharowsky-Str. 1, 91058 Erlangen (Germany); Russell, P. St. J. [Max Planck Institute for the Science of Light, Günther-Scharowsky-Str. 1, 91058 Erlangen (Germany); Department of Physics, University of Erlangen-Nuremberg, Günther-Scharowsky-Str. 1, 91058 Erlangen (Germany)

    2013-12-23

    A technique for optically accessing ultra-high vacuum environments, via a photonic-crystal fiber with a long small hollow core, is described. The small core and the long bore enable a pressure ratio of over 10{sup 8} to be maintained between two environments, while permitting efficient and unimpeded delivery of light, including ultrashort optical pulses. This delivery can be either passive or can encompass nonlinear optical processes such as optical pulse compression, deep UV generation, supercontinuum generation, or other useful phenomena.

  3. The evaluation of different environments in ultra-high frequency induction sintered powder metal compacts

    International Nuclear Information System (INIS)

    Cavdar, P. S.; Cavdar, U.

    2015-01-01

    The application of the iron based Powder Metal (PM) compacts in Ultra-High Frequency Induction Sintering (UHFIS) was reviewed for different environments. The three different environments: atmosphere, argon and vacuum were applied to the PM compacts. Iron based PM compacts were sintered at 1120 degree centigrade for a total of 550 seconds by using induction sintering machines with 2.8 kW power and 900 kHz frequency. Micro structural properties, densities, roughness and micro hardness values were obtained for all environments. The results were compared with each other. (Author)

  4. Assessment of the State of the Art of Ultra High Temperature Ceramics

    Science.gov (United States)

    Johnson, Sylvia; Gasch, Matt; Stackpoole, Mairead

    2009-01-01

    Ultra High Temperature Ceramics (UHTCs) are a family of materials that includes the borides, carbides and nitrides of hafnium-, zirconium- and titanium-based systems. UHTCs are famous for possessing some of the highest melting points of known materials. In addition, they are very hard, have good wear resistance, mechanical strength, and relatively high thermal conductivities (compared to other ceramic materials). Because of these attributes, UHTCs are ideal for thermal protection systems, especially those that require chemical and structural stability at extremely high operating temperatures. UHTCs have the potential to revolutionize the aerospace industry by enabling the development of sharp hypersonic vehicles or atmospheric entry probes capable of the most extreme entry conditions.

  5. Inverse problem for extragalactic transport of ultra-high energy cosmic rays

    International Nuclear Information System (INIS)

    Ptuskin, V.S.; Rogovaya, S.I.; Zirakashvili, V.N.

    2015-01-01

    The energy spectra and composition of ultra-high energy cosmic rays are changing in a course of propagation in the expanding Universe filled with background radiation. We developed a numerical code for solution of inverse problem for cosmic-ray transport equations that allows the determination of average source spectra of different nuclei from the cosmic ray spectra observed at the Earth. Employing this approach, the injection spectra of protons and Iron nuclei in extragalactic sources are found assuming that only these species are accelerated at the source. The data from the Auger experiment and the combined data from the Telescope Array + HiRes experiments are used to illustrate the method

  6. Inverse problem for extragalactic transport of ultra-high energy cosmic rays

    Energy Technology Data Exchange (ETDEWEB)

    Ptuskin, V.S.; Rogovaya, S.I.; Zirakashvili, V.N., E-mail: vptuskin@izmiran.ru, E-mail: rogovaya@izmiran.ru, E-mail: zirak@izmiran.ru [Pushkov Institute of Terrestrial Magnetism, Ionosphere and Radio Wave Propagation of the Russian Academy of Sciences (IZMIRAN), Troitsk, Moscow, 142190 (Russian Federation)

    2015-03-01

    The energy spectra and composition of ultra-high energy cosmic rays are changing in a course of propagation in the expanding Universe filled with background radiation. We developed a numerical code for solution of inverse problem for cosmic-ray transport equations that allows the determination of average source spectra of different nuclei from the cosmic ray spectra observed at the Earth. Employing this approach, the injection spectra of protons and Iron nuclei in extragalactic sources are found assuming that only these species are accelerated at the source. The data from the Auger experiment and the combined data from the Telescope Array + HiRes experiments are used to illustrate the method.

  7. Ultra-High-Resolution Computed Tomography of the Lung: Image Quality of a Prototype Scanner

    OpenAIRE

    Kakinuma, Ryutaro; Moriyama, Noriyuki; Muramatsu, Yukio; Gomi, Shiho; Suzuki, Masahiro; Nagasawa, Hirobumi; Kusumoto, Masahiko; Aso, Tomohiko; Muramatsu, Yoshihisa; Tsuchida, Takaaki; Tsuta, Koji; Maeshima, Akiko Miyagi; Tochigi, Naobumi; Watanabe, Shun-ichi; Sugihara, Naoki

    2015-01-01

    Purpose: The image noise and image quality of a prototype ultra-high-resolution computed tomography (U-HRCT) scanner was evaluated and compared with those of conventional high-resolution CT (C-HRCT) scanners. Materials and Methods: This study was approved by the institutional review board. A U-HRCT scanner prototype with 0.25 mm × 4 rows and operating at 120 mAs was used. The C-HRCT images were obtained using a 0.5 mm × 16 or 0.5 mm × 64 detector-row CT scanner operating at 150 mAs. Images fr...

  8. The characteristics of ultra-high performance concrete and cracking behavior of reinforced concrete tensile specimens

    Directory of Open Access Journals (Sweden)

    H.A. Rahdar

    2016-09-01

    Full Text Available The tensile behavior of concrete depends on some factors such as member dimensions, reinforcement ratio, diameter of rebar, strength and elasticity modulus of material. In this research the experimental method is used to examine the characteristics and the behavior of ultra-high performance concrete on the tensile behavior of concrete members reinforced by steel rebar. The results show that increasing the rebar cover on diameter rebar ratio (C/d increases the initial stiffening before the cracking stage in concrete. Also, by increasing of reinforcement ratio the cracking space decreased.

  9. Motivation for an SSC detector with ultra-high resolution photon detection

    International Nuclear Information System (INIS)

    Gunion, J.F.; Kane, G.

    1992-01-01

    It is well known that incorporating ultra-high resolution photon detection into a general purpose detector for the SSC will be extremely difficult. The authors will argue that the physics signals that could be missed without such resolution are of such importance that a special purpose detector designed specifically for photon final state modes should be constructed, if sufficient resolution cannot be achieved with general purpose detectors. The potentially great value of these signals as a probe of extremely high mass scales is stressed

  10. Optical Characteristics of a Multichannel Hybrid Integrated Light Source for Ultra-High-Bandwidth Optical Interconnections

    Directory of Open Access Journals (Sweden)

    Takanori Shimizu

    2015-11-01

    Full Text Available The optical characteristics of a multi-channel hybrid integrated light source were described for an optical interconnection with a bandwidth of over 10 Tbit/s. The power uniformity of the relative intensity of a 1000-channel light source was shown, and the minimum standard deviation s of the optical power of the 200 output ports at each 25-channel laser diode (LD array was estimated to be 0.49 dB. This hybrid integrated light source is expected to be easily adaptable to a photonics-electronics convergence system for ultra-high-bandwidth interchip interconnections.

  11. Ultra high speed framing photographs of laser produced plasmas using a picosecond optical shutter

    International Nuclear Information System (INIS)

    Gillman, G.B.; Ramsden, S.A.

    1975-01-01

    A study has been carried out of the spatial transmission properties of the optical Kerr effect shutter and it has been used to take ultra high speed framing photographs of laser produced plasmas in air and from solid targets. With a 1cm long CS 2 cell of aperture 5cm 2 a transmission of approximately 5% and an on/off contrast ratio of 10 4 was obtained. An image intensifier was necessary to obtain adequately exposed photographs of the plasma and the overall spatial resolution of the system was approximately 2μ. (author)

  12. The effect of cognitive remediation in individuals at ultra-high risk for psychosis

    DEFF Research Database (Denmark)

    Glenthøj, Louise Birkedal; Hjorthøj, Carsten; Kristensen, Tina Dam

    2017-01-01

    of five studies that reported a cognitive outcome found cognitive remediation to improve cognition in the domains of verbal memory, attention, and processing speed. Two out of four studies that reported on functional outcome found cognitive remediation to improve the functional outcome in the domains...... of social functioning and social adjustment. Zero out of the five studies that reported such an outcome found cognitive remediation to affect the magnitude of clinical symptoms. Research on the effect of cognitive remediation in the ultra-high risk state is still scarce. The current state of evidence...

  13. O-Ring sealing arrangements for ultra-high vacuum systems

    Science.gov (United States)

    Kim, Chang-Kyo; Flaherty, Robert

    1981-01-01

    An all metal reusable O-ring sealing arrangement for sealing two concentric tubes in an ultra-high vacuum system. An O-ring of a heat recoverable alloy such as Nitinol is concentrically positioned between protruding sealing rings of the concentric tubes. The O-ring is installed between the tubes while in a stressed martensitic state and is made to undergo a thermally induced transformation to an austenitic state. During the transformation the O-ring expands outwardly and contracts inwardly toward a previously sized austenitic configuration, thereby sealing against the protruding sealing rings of the concentric tubes.

  14. Ultra high temperature latent heat energy storage and thermophotovoltaic energy conversion

    OpenAIRE

    Datas Medina, Alejandro; Ramos Cabal, Alba; Martí Vega, Antonio; Cañizo Nadal, Carlos del; Luque López, Antonio

    2016-01-01

    A conceptual energy storage system design that utilizes ultra high temperature phase change materials is presented. In this system, the energy is stored in the form of latent heat and converted to electricity upon demand by TPV (thermophotovoltaic) cells. Silicon is considered in this study as PCM (phase change material) due to its extremely high latent heat (1800 J/g or 500 Wh/kg), melting point (1410 C), thermal conductivity (~25 W/mK), low cost (less than $2/kg or $4/kWh) and a...

  15. The global lambda visualization facility: An international ultra-high-definition wide-area visualization collaboratory

    Science.gov (United States)

    Leigh, J.; Renambot, L.; Johnson, Aaron H.; Jeong, B.; Jagodic, R.; Schwarz, N.; Svistula, D.; Singh, R.; Aguilera, J.; Wang, X.; Vishwanath, V.; Lopez, B.; Sandin, D.; Peterka, T.; Girado, J.; Kooima, R.; Ge, J.; Long, L.; Verlo, A.; DeFanti, T.A.; Brown, M.; Cox, D.; Patterson, R.; Dorn, P.; Wefel, P.; Levy, S.; Talandis, J.; Reitzer, J.; Prudhomme, T.; Coffin, T.; Davis, B.; Wielinga, P.; Stolk, B.; Bum, Koo G.; Kim, J.; Han, S.; Corrie, B.; Zimmerman, T.; Boulanger, P.; Garcia, M.

    2006-01-01

    The research outlined in this paper marks an initial global cooperative effort between visualization and collaboration researchers to build a persistent virtual visualization facility linked by ultra-high-speed optical networks. The goal is to enable the comprehensive and synergistic research and development of the necessary hardware, software and interaction techniques to realize the next generation of end-user tools for scientists to collaborate on the global Lambda Grid. This paper outlines some of the visualization research projects that were demonstrated at the iGrid 2005 workshop in San Diego, California.

  16. Search for emission of ultra high energy radiation from active galactic nuclei

    International Nuclear Information System (INIS)

    1993-01-01

    A search for emission of ultra-high energy gamma radiation from 13 active galactic nuclei that were detected by EGRET, using the CYGNUS extensive air-shower array, is described. The data set has been searched for continuous emission, emission on the time scale of one week, and for on the time scale of out day. No evidence for emission from any of the AGN on any of the time scales examined was found. The 90% C.L. upper limit to the continuous flux from Mrk 421 above 50 TeV is 7.5 x 10 -14 cm -2 s -1

  17. Effects of gamma irradiation on the molecular structure and mechanical properties of biodegradable polymer poly(hydroxybutyrate)

    International Nuclear Information System (INIS)

    Oliveira, Leticia M. de; Araujo, Elmo S.

    2005-01-01

    The effects of gamma irradiation ( 60 Co) on the properties of the Brazilian biodegradable polymer, Poly(hydroxybutyrate), PHB, i.e. chemical, mechanical and structural properties were investigated. PHB is a natural polyester biosynthesized by different bacteria as a form to store carbon and energy. This new biopolymer shows a great potential in the medical and pharmaceutical applications due to the biocompatibility and biodegradation capacity, since it is reabsorbed by organism without liberation of toxic substances. As it.s well known, gamma irradiation have been considered the more functional sterilization mechanism applied to medical devices. This way, it is necessary to know the effects caused by energy transfer to the polymer system. The viscosity-average molar mass (Mv) of the irradiated PHB, measured using an Ostwald-type capillary viscometer, significantly decreased. The irradiated samples (test specimens) showed a molecular degradation degree, G (scissions/100 eV) value, in the sterilization dose range (0-25 kGy) about 11.4, and 20.9 to doses above 35 kGy. Other results also indicate that the gamma irradiation significantly affected the mechanical properties of PHB. Tensile strength, impact strength and elongation at break decreased dramatically, indicating increasing on the brittleness, because significant chain scissions take place in the amorphous region of irradiated PHB. On the other hand, Young modulus does not significantly change on irradiated polymer. 13 C NMR spectra of irradiated PHB at dose of 200 kGy did not show arising of new structural groups. (author)

  18. A molecular dynamics simulation study of irradiation induced defects in gold nanowire

    Science.gov (United States)

    Liu, Wenqiang; Chen, Piheng; Qiu, Ruizhi; Khan, Maaz; Liu, Jie; Hou, Mingdong; Duan, Jinglai

    2017-08-01

    Displacement cascade in gold nanowires was studied using molecular dynamics computer simulations. Primary knock-on atoms (PKAs) with different kinetic energies were initiated either at the surface or at the center of the nanowires. We found three kinds of defects that were induced by the cascade, including point defects, stacking faults and crater at the surface. The starting points of PKAs influence the number of residual point defects, and this consequently affect the boundary of anti-radiation window which was proposed by calculation of diffusion of point defects to the free surface of nanowires. Formation of stacking faults that expanded the whole cross-section of gold nanowires was observed when the PKA's kinetic energy was higher than 5 keV. Increasing the PKA's kinetic energy up to more than 10 keV may lead to the formation of crater at the surface of nanowires due to microexplosion of hot atoms. At this energy, PKAs started from the center of nanowires can also result in the creation of crater because length of cascade region is comparable to diameter of nanowires. Both the two factors, namely initial positions of PKAs as well as the craters induced by higher energy irradiation, would influence the ability of radiation resistance of metal nanowires.

  19. Molecular dynamics simulations of the role of electronic losses in damage creation of ion irradiated Tungsten

    International Nuclear Information System (INIS)

    Maya, P.N.; Deshpande, S.P

    2014-01-01

    Damage creation due to the irradiation of 14 MeV fusion neutrons and the subsequent mechanical failure and alteration of the fuel retention properties of tungsten plasma-facing materials is one of the major concerns of the fusion reactors. In addition to nuclear reactions and the subsequent transmutations, the energetic neutron impars its kinetic energy either partly or completely to a lattice tungsten atom thereby creating a primary knock-on atom (PKA) which, is considered as the onset of damage creation in the lattice. The PKA continues to undergo collisions with the lattice atoms which eventually leads to a collision cascade. In order to understand the collision process, one often simulates such systems using surrogate ions, such as energetic W ions itself, in particle accelerators and due to the experimental constraints (such as the stability of the beam) one often has to opt for high energetic ion beams (∼ 30 MeV) which surpasses the PKA energies created by neutron (∼100s of KeV) in W. Hence it is important to distinguish how the very high energetic tungsten atoms interact with the lattice atoms in comparison with the low energy PKA created by the neutron. One of the key difference is that at higher energies the electronic losses become important which decides the collision dynamics. In this presentation the effect of electronic losses in the damage creation using molecular dynamics simulations have been discussed

  20. Molecular dynamics study of interstitial-solute interactions in irradiated alloys

    International Nuclear Information System (INIS)

    Lam, N.Q.; Doan, N.V.; Adda, Y.

    1980-01-01

    The molecular dynamics technique has been used, in conjunction with the interionic potentials of Dagens et al, to study the stability, configuration, binding, and induced migration of mixed dumbbells in an irradiated Al-Zn alloy. For the purpose of comparisons, self-interstitials in pure Al were also investigated. The Al-Al and Al-Zn interactions were described by pair potentials which extended to ninth-neighbour distances. Both the self-interstitial dumbbell and the mixed dumbbell were found to be stable in the configuration. The formation energy of the self-interstitial is 2.89 eV and the mixed-dumbbell binding energy is 0.38 eV. As a result of this strong binding, the threshold energy required to induce the migration of the mixed dumbbell is about 1.2 eV, which is significantly larger than the minimum energy of about 0.15 eV transferred to a self-interstitial to induce its jumps in pure Al. Caging motions of the mixed dumbbell were observed. The present computer-simulation results are compared with experimental measurements. (author)

  1. Effects of anesthetic agents on brain blood oxygenation level revealed with ultra-high field MRI.

    Directory of Open Access Journals (Sweden)

    Luisa Ciobanu

    Full Text Available During general anesthesia it is crucial to control systemic hemodynamics and oxygenation levels. However, anesthetic agents can affect cerebral hemodynamics and metabolism in a drug-dependent manner, while systemic hemodynamics is stable. Brain-wide monitoring of this effect remains highly challenging. Because T(2*-weighted imaging at ultra-high magnetic field strengths benefits from a dramatic increase in contrast to noise ratio, we hypothesized that it could monitor anesthesia effects on brain blood oxygenation. We scanned rat brains at 7T and 17.2T under general anesthesia using different anesthetics (isoflurane, ketamine-xylazine, medetomidine. We showed that the brain/vessels contrast in T(2*-weighted images at 17.2T varied directly according to the applied pharmacological anesthetic agent, a phenomenon that was visible, but to a much smaller extent at 7T. This variation is in agreement with the mechanism of action of these agents. These data demonstrate that preclinical ultra-high field MRI can monitor the effects of a given drug on brain blood oxygenation level in the absence of systemic blood oxygenation changes and of any neural stimulation.

  2. Quality of Experience for Large Ultra-High-Resolution Tiled Displays with Synchronization Mismatch

    Directory of Open Access Journals (Sweden)

    Deshpande Sachin

    2011-01-01

    Full Text Available This paper relates to quality of experience when viewing images, video, or other content on large ultra-high-resolution displays made from individual display tiles. We define experiments to measure vernier acuity caused by synchronization mismatch for moving images. The experiments are used to obtain synchronization mismatch acuity threshold as a function of object velocity and as a function of occlusion or gap width. Our main motivation for measuring the synchronization mismatch vernier acuity is its relevance in the application of tiled display systems, which create a single contiguous image using individual discrete panels arranged in a matrix with each panel utilizing a distributed synchronization algorithm to display parts of the overall image. We also propose a subjective assessment method for perception evaluation of synchronization mismatch for large ultra-high-resolution tiled displays. For this, we design a synchronization mismatch measurement test video set for various tile configurations for various interpanel synchronization mismatch values. The proposed method for synchronization mismatch perception can evaluate tiled displays with or without tile bezels. The results from this work can help during design of low-cost tiled display systems, which utilize distributed synchronization mechanisms for a contiguous or bezeled image display.

  3. Bayesian Multiresolution Variable Selection for Ultra-High Dimensional Neuroimaging Data.

    Science.gov (United States)

    Zhao, Yize; Kang, Jian; Long, Qi

    2018-01-01

    Ultra-high dimensional variable selection has become increasingly important in analysis of neuroimaging data. For example, in the Autism Brain Imaging Data Exchange (ABIDE) study, neuroscientists are interested in identifying important biomarkers for early detection of the autism spectrum disorder (ASD) using high resolution brain images that include hundreds of thousands voxels. However, most existing methods are not feasible for solving this problem due to their extensive computational costs. In this work, we propose a novel multiresolution variable selection procedure under a Bayesian probit regression framework. It recursively uses posterior samples for coarser-scale variable selection to guide the posterior inference on finer-scale variable selection, leading to very efficient Markov chain Monte Carlo (MCMC) algorithms. The proposed algorithms are computationally feasible for ultra-high dimensional data. Also, our model incorporates two levels of structural information into variable selection using Ising priors: the spatial dependence between voxels and the functional connectivity between anatomical brain regions. Applied to the resting state functional magnetic resonance imaging (R-fMRI) data in the ABIDE study, our methods identify voxel-level imaging biomarkers highly predictive of the ASD, which are biologically meaningful and interpretable. Extensive simulations also show that our methods achieve better performance in variable selection compared to existing methods.

  4. Manganese oxide micro-supercapacitors with ultra-high areal capacitance

    Science.gov (United States)

    Wang, Xu; Myers, Benjamin D.; Yan, Jian; Shekhawat, Gajendra; Dravid, Vinayak; Lee, Pooi See

    2013-05-01

    A symmetric micro-supercapacitor is constructed by electrochemically depositing manganese oxide onto micro-patterned current collectors. High surface-to-volume ratio of manganese oxide and short diffusion distance between electrodes give an ultra-high areal capacitance of 56.3 mF cm-2 at a current density of 27.2 μA cm-2.A symmetric micro-supercapacitor is constructed by electrochemically depositing manganese oxide onto micro-patterned current collectors. High surface-to-volume ratio of manganese oxide and short diffusion distance between electrodes give an ultra-high areal capacitance of 56.3 mF cm-2 at a current density of 27.2 μA cm-2. Electronic supplementary information (ESI) available: Experimental procedures; optical images of micro-supercapacitors; areal capacitances of samples M-0.3C, M-0.6C and M-0.9C; illustration of interdigital finger electrodes; Nyquist plot of Co(OH)2 deposited on micro-electrodes. See DOI: 10.1039/c3nr00210a

  5. New solid laser: Ceramic laser. From ultra stable laser to ultra high output laser

    International Nuclear Information System (INIS)

    Ueda, Kenichi

    2006-01-01

    An epoch-making solid laser is developed. It is ceramic laser, polycrystal, which is produced as same as glass and shows ultra high output. Ti 3+ :Al 2 O 3 laser crystal and the CPA (chirped pulse amplification) technique realized new ultra high output lasers. Japan has developed various kinds of ceramic lasers, from 10 -2 to 67 x 10 3 w average output, since 1995. These ceramic lasers were studied by gravitational radiation astronomy. The scattering coefficient of ceramic laser is smaller than single crystals. The new fast ignition method is proposed by Institute of Laser Engineering of Osaka University, Japan. Ultra-intense short pulse laser can inject the required energy to the high-density imploded core plasma within the core disassembling time. Ti 3+ :Al 2 O 3 crystal for laser, ceramic YAG of large caliber for 100 kW, transparent laser ceramic from nano-crystals, crystal grain and boundary layer between grains, the scattering coefficient of single crystal and ceramic, and the derived release cross section of Yb:YAG ceramic are described. (S.Y.)

  6. Physicochemical properties and storage stability of soybean protein nanoemulsions prepared by ultra-high pressure homogenization.

    Science.gov (United States)

    Xu, Jing; Mukherjee, Dipaloke; Chang, Sam K C

    2018-02-01

    This study investigated the effects of the ultrahigh pressure homogenization (pressure, protein concentration, oil phase fraction, pH, temperature, and ionic strength) and storage on the properties of nanoemulsions (100-500nm range), which were stabilized by laboratory-prepared soybean protein isolate (SPI), β-conglycinin (7S) and glycinin (11S). The nanoemulsions made with SPI, 7S and 11S proteins exhibited considerable stability over various ionic strengths (0-500mM NaCl), pH (7), thermal treatments (30-60°C) and storage (0-45days). The far-UV spectra of SPI, 7S, 11S dispersions, and SPI-, 7S-, 11S protein-stabilized nanoemulsions were analyzed for the protein structural changes following lipid removal. The ultra-high pressure homogenization changed the secondary structure of SPI, 7S, 11S proteins in the nanoemulsions, and enhanced their stability. This study demonstrated that SPI, 7S, and 11S proteins can be used as effective emulsifiers in nanoemulsions prepared by ultra-high pressure homogenization. Copyright © 2017. Published by Elsevier Ltd.

  7. Behavior and strength of beams cast with ultra high strength concrete containing different types of fibers

    Directory of Open Access Journals (Sweden)

    M.M. Kamal

    2014-04-01

    Full Text Available Ultra-high performance concrete (UHPC is a special type of concrete with extraordinary potentials in terms of strength and durability performance. Its production and application implement the most up-to-date knowledge and technology of concrete manufacturing. Sophisticated structural designs in bridges and high-rise buildings, repair works and special structures like nuclear facilities are currently the main fields of applications of UHPC. This paper aimed to evaluate the behavior of ultra-high strength concrete beams. This paper also aimed to determine the effect of adding fibers and explore their effect upon the behavior and strength of the reinforced concrete beams. A total of twelve simple concrete beams with and without shear reinforcements were tested in flexure. The main variables taken into consideration in this research were the type of fibers and the percentage of longitudinal reinforcement as well as the existence or absence of the web reinforcement. Two types of fibers were used including steel and polypropylene fibers. The behavior of the tested beams was investigated with special attention to the deflection under different stages of loading, initial cracking, cracking pattern, and ultimate load. Increased number of cracks was observed at the end of loading due to the use of fibers, which led to the reduced width of cracks. This led to increased stiffness and higher values of maximum loads.

  8. Fracture Mechanisms of Zirconium Diboride Ultra-High Temperature Ceramics under Pulse Loading

    Science.gov (United States)

    Skripnyak, Vladimir V.; Bragov, Anatolii M.; Skripnyak, Vladimir A.; Lomunov, Andrei K.; Skripnyak, Evgeniya G.; Vaganova, Irina K.

    2015-06-01

    Mechanisms of failure in ultra-high temperature ceramics (UHTC) based on zirconium diboride under pulse loading were studied experimentally by the method of SHPB and theoretically using the multiscale simulation method. The obtained experimental and numerical data are evidence of the quasi-brittle fracture character of nanostructured zirconium diboride ceramics under compression and tension at high strain rates and the room temperatures. Damage of nanostructured porous zirconium diboride -based UHTC can be formed under stress pulse amplitude below the Hugoniot elastic limit. Fracture of nanostructured ultra-high temperature ceramics under pulse and shock-wave loadings is provided by fast processes of intercrystalline brittle fracture and relatively slow processes of quasi-brittle failure via growth and coalescence of microcracks. A decrease of the shear strength can be caused by nano-voids clusters in vicinity of triple junctions between ceramic matrix grains and ultrafine-grained ceramics. This research was supported by grants from ``The Tomsk State University Academic D.I. Mendeleev Fund Program'' and also N. I. Lobachevski State University of Nizhny Novgorod (Grant of post graduate mobility).

  9. Nanocomposites of TiO2/cyanoethylated cellulose with ultra high dielectric constants

    International Nuclear Information System (INIS)

    Madusanka, Nadeesh; Shivareddy, Sai G; Hiralal, Pritesh; Choi, Youngjin; Amaratunga, Gehan A J; Eddleston, Mark D; Oliver, Rachel A

    2016-01-01

    A novel dielectric nanocomposite containing a high permittivity polymer, cyanoethylated cellulose (CRS) and TiO 2 nanoparticles was successfully prepared with different weight percentages (10%, 20% and 30%) of TiO 2 . The intermolecular interactions and morphology within the polymer nanocomposites were analysed. TiO 2 /CRS nanofilms on SiO 2 /Si wafers were used to form metal–insulator–metal type capacitors. Capacitances and loss factors in the frequency range of 1 kHz–1 MHz were measured. At 1 kHz CRS-TiO 2 nanocomposites exhibited ultra high dielectric constants of 118, 176 and 207 for nanocomposites with 10%, 20% and 30% weight of TiO 2 respectively, significantly higher than reported values of pure CRS (21), TiO 2 (41) and other dielectric polymer-TiO 2 nanocomposite films. Furthermore, all three CRS-TiO 2 nanocomposites show a loss factor <0.3 at 1 kHz and low leakage current densities (10 −6 –10 −7 A cm −2 ). Leakage was studied using conductive atomic force microscopy and it was observed that the leakage is associated with TiO 2 nanoparticles embedded in the CRS polymer matrix. A new class of ultra high dielectric constant hybrids using nanoscale inorganic dielectrics dispersed in a high permittivity polymer suitable for energy management applications is reported. (paper)

  10. The MIDAS telescope for microwave detection of ultra-high energy cosmic rays

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez-Muñiz, J. [Universidad de Santiago de Compostela, Departamento de Física de Partículas, Campus Sur, Universidad, E-15782 Santiago de Compostela (Spain); Amaral Soares, E. [Universidade Federal do Rio de Janeiro, Instituto de Física, Cidade Universitaria, Caixa Postal 68528, 21945-970 Rio de Janeiro, RJ (Brazil); Berlin, A.; Bogdan, M. [University of Chicago, Enrico Fermi Institute and Kavli Institute for Cosmological Physics, 5640 S. Ellis Ave., Chicago, IL 60637 (United States); Boháčová, M. [University of Chicago, Enrico Fermi Institute and Kavli Institute for Cosmological Physics, 5640 S. Ellis Ave., Chicago, IL 60637 (United States); Institute of Physics of the Academy of Sciences of the Czech Republic, Na Slovance 2, CZ-182 21 Praha 8 (Czech Republic); Bonifazi, C. [Universidade Federal do Rio de Janeiro, Instituto de Física, Cidade Universitaria, Caixa Postal 68528, 21945-970 Rio de Janeiro, RJ (Brazil); Carvalho, W.R. [Universidad de Santiago de Compostela, Departamento de Física de Partículas, Campus Sur, Universidad, E-15782 Santiago de Compostela (Spain); Mello Neto, J.R.T. de [Universidade Federal do Rio de Janeiro, Instituto de Física, Cidade Universitaria, Caixa Postal 68528, 21945-970 Rio de Janeiro, RJ (Brazil); Facal San Luis, P., E-mail: facal@kicp.uchicago.edu [University of Chicago, Enrico Fermi Institute and Kavli Institute for Cosmological Physics, 5640 S. Ellis Ave., Chicago, IL 60637 (United States); Genat, J.F.; Hollon, N.; Mills, E.; Monasor, M.; Privitera, P. [University of Chicago, Enrico Fermi Institute and Kavli Institute for Cosmological Physics, 5640 S. Ellis Ave., Chicago, IL 60637 (United States); and others

    2013-08-11

    We present the design, implementation and data taking performance of the MIcrowave Detection of Air Showers (MIDAS) experiment, a large field of view imaging telescope designed to detect microwave radiation from extensive air showers induced by ultra-high energy cosmic rays. This novel technique may bring a tenfold increase in detector duty cycle when compared to the standard fluorescence technique based on detection of ultraviolet photons. The MIDAS telescope consists of a 4.5 m diameter dish with a 53-pixel receiver camera, instrumented with feed horns operating in the commercial extended C-Band (3.4–4.2 GHz). A self-trigger capability is implemented in the digital electronics. The main objectives of this first prototype of the MIDAS telescope – to validate the telescope design, and to demonstrate a large detector duty cycle – were successfully accomplished in a dedicated data taking run at the University of Chicago campus prior to installation at the Pierre Auger Observatory. -- Highlights: • The MIDAS objective is to detect ultra high energy cosmic rays using microwaves. • GHz radiation could provide a powerful alternative to current detection methods. • The MIDAS prototype explores the potential of the microwave technique.

  11. The MIDAS telescope for microwave detection of ultra-high energy cosmic rays

    International Nuclear Information System (INIS)

    Alvarez-Muñiz, J.; Amaral Soares, E.; Berlin, A.; Bogdan, M.; Boháčová, M.; Bonifazi, C.; Carvalho, W.R.; Mello Neto, J.R.T. de; Facal San Luis, P.; Genat, J.F.; Hollon, N.; Mills, E.; Monasor, M.; Privitera, P.

    2013-01-01

    We present the design, implementation and data taking performance of the MIcrowave Detection of Air Showers (MIDAS) experiment, a large field of view imaging telescope designed to detect microwave radiation from extensive air showers induced by ultra-high energy cosmic rays. This novel technique may bring a tenfold increase in detector duty cycle when compared to the standard fluorescence technique based on detection of ultraviolet photons. The MIDAS telescope consists of a 4.5 m diameter dish with a 53-pixel receiver camera, instrumented with feed horns operating in the commercial extended C-Band (3.4–4.2 GHz). A self-trigger capability is implemented in the digital electronics. The main objectives of this first prototype of the MIDAS telescope – to validate the telescope design, and to demonstrate a large detector duty cycle – were successfully accomplished in a dedicated data taking run at the University of Chicago campus prior to installation at the Pierre Auger Observatory. -- Highlights: • The MIDAS objective is to detect ultra high energy cosmic rays using microwaves. • GHz radiation could provide a powerful alternative to current detection methods. • The MIDAS prototype explores the potential of the microwave technique

  12. Radio reconstruction of the mass of ultra-high cosmic rays

    Energy Technology Data Exchange (ETDEWEB)

    Dorosti, Qader [Institut fuer Kernphysik (IKP), KIT (Germany)

    2015-07-01

    Detection of ultra-high energy cosmic rays can reveal the processes of the most violent sources in the Universe, which yet has to be determined. Interaction of cosmic rays with the Earth's atmosphere results in cascades of secondary particles, i.e. air showers. Many of such particles are electrons and positrons. The induced electrons and positrons interact with the geomagnetic field and induce radio emissions. Detection of air showers along with the detection of induced radio emissions can furnish a precise measurement of the direction, energy and mass of ultra-high energy cosmic rays. The Auger Engineering Radio Array consists of 124 radio stations measuring radio emission from air showers, in order to reconstruct the energy, direction and mass of cosmic rays. In this contribution, we present a method which employs a reduced hyperbolic model to describe the shape of radio wave front. We have investigated that the parameters of the reduced hyperbolic model are sensitive to the mass of cosmic rays. The obtained results are presented in this talk.

  13. Ultra-high resolution flat-panel volume CT: fundamental principles, design architecture, and system characterization

    International Nuclear Information System (INIS)

    Gupta, Rajiv; Brady, Tom; Grasruck, Michael; Suess, Christoph; Schmidt, Bernhard; Stierstorfer, Karl; Popescu, Stefan; Flohr, Thomas; Bartling, Soenke H.

    2006-01-01

    Digital flat-panel-based volume CT (VCT) represents a unique design capable of ultra-high spatial resolution, direct volumetric imaging, and dynamic CT scanning. This innovation, when fully developed, has the promise of opening a unique window on human anatomy and physiology. For example, the volumetric coverage offered by this technology enables us to observe the perfusion of an entire organ, such as the brain, liver, or kidney, tomographically (e.g., after a transplant or ischemic event). By virtue of its higher resolution, one can directly visualize the trabecular structure of bone. This paper describes the basic design architecture of VCT. Three key technical challenges, viz., scatter correction, dynamic range extension, and temporal resolution improvement, must be addressed for successful implementation of a VCT scanner. How these issues are solved in a VCT prototype and the modifications necessary to enable ultra-high resolution volumetric scanning are described. The fundamental principles of scatter correction and dose reduction are illustrated with the help of an actual prototype. The image quality metrics of this prototype are characterized and compared with a multi-detector CT (MDCT). (orig.)

  14. Concept of modular flexure-based mechanisms for ultra-high precision robot design

    Directory of Open Access Journals (Sweden)

    M. Richard

    2011-05-01

    Full Text Available This paper introduces a new concept of modular flexure-based mechanisms to design industrial ultra-high precision robots, which aims at significantly reducing both the complexity of their design and their development time. This modular concept can be considered as a robotic Lego, where a finite number of building bricks is used to quickly build a high-precision robot. The core of the concept is the transformation of a 3-D design problem into several 2-D ones, which are simpler and well-mastered. This paper will first briefly present the theoretical bases of this methodology and the requirements of both types of building bricks: the active and the passive bricks. The section dedicated to the design of the active bricks will detail the current research directions, mainly the maximisation of the strokes and the development of an actuation sub-brick. As for the passive bricks, some examples will be presented, and a discussion regarding the establishment of a mechanical solution catalogue will conclude the section. Last, this modular concept will be illustrated with a practical example, consisting in the design of a 5-degree of freedom ultra-high precision robot.

  15. Improvement of performance of ultra-high performance concrete based composite material added with nano materials

    Directory of Open Access Journals (Sweden)

    Pang Jinchang

    2016-03-01

    Full Text Available Ultra-high performance concrete (UHPC, a kind of composite material characterized by ultra high strength, high toughness and high durability. It has a wide application prospect in engineering practice. But there are some defects in concrete. How to improve strength and toughness of UHPC remains to be the target of researchers. To obtain UHPC with better performance, this study introduced nano-SiO2 and nano-CaCO3 into UHPC. Moreover, hydration heat analysis, X-Ray Diffraction (XRD, mercury intrusion porosimetry (MIP and nanoindentation tests were used to explore hydration process and microstructure. Double-doped nanomaterials can further enhance various mechanical performances of materials. Nano-SiO2 can promote early progress of cement hydration due to its high reaction activity and C-S-H gel generates when it reacts with cement hydration product Ca(OH2. Nano-CaCO3 mainly plays the role of crystal nucleus effect and filling effect. Under the combined action of the two, the composite structure is denser, which provides a way to improve the performance of UHPC in practical engineering.

  16. High rate response of ultra-high-performance fiber-reinforced concretes under direct tension

    Energy Technology Data Exchange (ETDEWEB)

    Tran, Ngoc Thanh [Department of Civil and Environmental Engineering, Sejong University, 98 Gunja-Dong, Gwangjin-Gu, Seoul 143-747 (Korea, Republic of); Tran, Tuan Kiet [Department of Civil and Environmental Engineering, Sejong University, 98 Gunja-Dong, Gwangjin-Gu, Seoul 143-747 (Korea, Republic of); Department of Civil Engineering and Applied Mechanics, Ho Chi Minh City University of Technology and Education, 01 Vo Van Ngan, Thu Duc District, Ho Chi Minh City (Viet Nam); Kim, Dong Joo, E-mail: djkim75@sejong.ac.kr [Department of Civil and Environmental Engineering, Sejong University, 98 Gunja-Dong, Gwangjin-Gu, Seoul 143-747 (Korea, Republic of)

    2015-03-15

    The tensile response of ultra-high-performance fiber-reinforced concretes (UHPFRCs) at high strain rates (5–24 s{sup −} {sup 1}) was investigated. Three types of steel fibers, including twisted, long and short smooth steel fibers, were added by 1.5% volume content in an ultra high performance concrete (UHPC) with a compressive strength of 180 MPa. Two different cross sections, 25 × 25 and 25 × 50 mm{sup 2}, of tensile specimens were used to investigate the effect of the cross section area on the measured tensile response of UHPFRCs. Although all the three fibers generated strain hardening behavior even at high strain rates, long smooth fibers produced the highest tensile resistance at high rates whereas twisted fiber did at static rate. The breakages of twisted fibers were observed from the specimens tested at high strain rates unlike smooth steel fibers. The tensile behavior of UHPFRCs at high strain rates was clearly influenced by the specimen size, especially in post-cracking strength.

  17. Ultra-high resolution flat-panel volume CT: fundamental principles, design architecture, and system characterization

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, Rajiv; Brady, Tom [Massachusetts General Hospital, Department of Radiology, Founders House, FND-2-216, Boston, MA (United States); Grasruck, Michael; Suess, Christoph; Schmidt, Bernhard; Stierstorfer, Karl; Popescu, Stefan; Flohr, Thomas [Siemens Medical Solutions, Forchheim (Germany); Bartling, Soenke H. [Hannover Medical School, Department of Neuroradiology, Hannover (Germany)

    2006-06-15

    Digital flat-panel-based volume CT (VCT) represents a unique design capable of ultra-high spatial resolution, direct volumetric imaging, and dynamic CT scanning. This innovation, when fully developed, has the promise of opening a unique window on human anatomy and physiology. For example, the volumetric coverage offered by this technology enables us to observe the perfusion of an entire organ, such as the brain, liver, or kidney, tomographically (e.g., after a transplant or ischemic event). By virtue of its higher resolution, one can directly visualize the trabecular structure of bone. This paper describes the basic design architecture of VCT. Three key technical challenges, viz., scatter correction, dynamic range extension, and temporal resolution improvement, must be addressed for successful implementation of a VCT scanner. How these issues are solved in a VCT prototype and the modifications necessary to enable ultra-high resolution volumetric scanning are described. The fundamental principles of scatter correction and dose reduction are illustrated with the help of an actual prototype. The image quality metrics of this prototype are characterized and compared with a multi-detector CT (MDCT). (orig.)

  18. Effects of anesthetic agents on brain blood oxygenation level revealed with ultra-high field MRI

    International Nuclear Information System (INIS)

    Ciobanu, Luisa; Reynaud, Olivier; Le Bihan, Denis; Uhrig, Lynn; Jarraya, Bechir

    2012-01-01

    During general anesthesia it is crucial to control systemic hemodynamics and oxygenation levels. However, anesthetic agents can affect cerebral hemodynamics and metabolism in a drug-dependent manner, while systemic hemodynamics is stable. Brain-wide monitoring of this effect remains highly challenging. Because T2'*-weighted imaging at ultra-high magnetic field strengths benefits from a dramatic increase in contrast to noise ratio, we hypothesized that it could monitor anesthesia effects on brain blood oxygenation. We scanned rat brains at 7 T and 17.2 T under general anesthesia using different anesthetics (isoflurane, ketamine-xylazine, medetomidine). We showed that the brain/vessels contrast in T2'*- weighted images at 17.2 T varied directly according to the applied pharmacological anesthetic agent, a phenomenon that was visible, but to a much smaller extent at 7 T. This variation is in agreement with the mechanism of action of these agents. These data demonstrate that preclinical ultra-high field MRI can monitor the effects of a given drug on brain blood oxygenation level in the absence of systemic blood oxygenation changes and of any neural stimulation. (authors)

  19. Encoding methods for B1+ mapping in parallel transmit systems at ultra high field

    Science.gov (United States)

    Tse, Desmond H. Y.; Poole, Michael S.; Magill, Arthur W.; Felder, Jörg; Brenner, Daniel; Jon Shah, N.

    2014-08-01

    Parallel radiofrequency (RF) transmission, either in the form of RF shimming or pulse design, has been proposed as a solution to the B1+ inhomogeneity problem in ultra high field magnetic resonance imaging. As a prerequisite, accurate B1+ maps from each of the available transmit channels are required. In this work, four different encoding methods for B1+ mapping, namely 1-channel-on, all-channels-on-except-1, all-channels-on-1-inverted and Fourier phase encoding, were evaluated using dual refocusing acquisition mode (DREAM) at 9.4 T. Fourier phase encoding was demonstrated in both phantom and in vivo to be the least susceptible to artefacts caused by destructive RF interference at 9.4 T. Unlike the other two interferometric encoding schemes, Fourier phase encoding showed negligible dependency on the initial RF phase setting and therefore no prior B1+ knowledge is required. Fourier phase encoding also provides a flexible way to increase the number of measurements to increase SNR, and to allow further reduction of artefacts by weighted decoding. These advantages of Fourier phase encoding suggest that it is a good choice for B1+ mapping in parallel transmit systems at ultra high field.

  20. Molecular weight distribution of electron and γ-ray irradiated PEEK measured by very high temperature GPC

    International Nuclear Information System (INIS)

    Nakahara, H.

    1996-01-01

    Poly(ether ether ketone)(PEEK) films were irradiated with electron beam in air and in helium. Gel fractions of the PEEK samples were determined as the ratio of the weight of insoluble fraction/total weigh by extracting the samples with 1-chloronaphthalene (1-CN) at 260degC. While unirradiated PEEK samples were dissolved in 1-CN completely, PEEK samples highly (10 - 50 MGy) irradiated in air were almost insoluble in the solvent. The weight-average molecular weight M w of soluble fractions of the samples were measured by very high temperature gel permeation chromatography (VHTGPC): it was found that the M w decreases with increasing dose. On the other hand, PEEK samples irradiated in helium gave gel fractions at lower doses (0 - 5 MGy) than in air. The PEEK films were also irradiated with 60 Co γ-rays in the dose range, i.e. from 0 to 5 MGy. The γ-irradiated PEEK samples were completely dissolved in 1-CN at 260degC. Their M w measured by VHTGPC decreases with increasing dose. (author)

  1. Phenotype and molecular analysis of M{sub 1} generation of stylosanthes irradiated by {sup 60}Co

    Energy Technology Data Exchange (ETDEWEB)

    Weili, Zhang [College of Life Sciences, Zhongkai University of Agriculture and Engineering, Guangzhou, Guangdong Province 510225 (China); Fengmin, Liu [Teaching and Science Research Base, Zhongkai College of Agriculture and Technology, Guangzhou, Guangdong Province 510225 (China)

    2012-05-15

    The seeds of Stylosanthes guianensis SW. ‘Reyan No.13’ were irradiated by {sup 60}Co at 0, 325, 487 and 974 Gy. Phenotype and molecular variations of Stylosanthes M{sub 1} generations were studied. Germination percentage, plant height, leaf length and stem diameter of M{sub 1} seedlings were determined using SRAP-PCR. Results showed that biological character indices of treatments were significantly lower than that of control (CK). Irradiation inhibited plant growth. Growth indices of 974 Gy treatment, except leaf length, were significantly lower than CK and other two treatments. Eight effective primers selected from 24 primers combination were used for SRAP-PCR. SRAP analysis revealed that the 57 of 88 DNA fragments were amplified showing polymorphisms. The average percentage of polymorphic bands was 64.77%. The effects of {sup 60}Coγ irradiation on DNA variation of seedlings were varied from different treatments. Numbers of polymorphic bands changed after irradiation. Coefficient of variation was in direct proportion to irradiation doses. Variation rates of 325 Gy, 487 Gy and 974 Gy treatments were 22.0%, 38.1% and 41.5%, respectively. The Nei’s genetic similarity coefficient of all treatments was ranged from 0.585 to 0.780 by software NTSYSpc 2.1 based on SRAP results and the average Nei's coefficient was 0.678. The Nei’s genetic similarity coefficient of 974 Gy treatment was 0.585 and variation degree was highest among all treatments, 487 Gy treatment was second and 325 Gy treatment was the lowest one. Based on present bands, four irradiated treatments were classified into two major groups by UPGMA cluster analysis. Group 1 included CK, 325 Gy and 487 Gy treatment and group 2 included 974 Gy. SRAP analysis determined variation of Stylosanthes after irradiation and the results of SRAP analysis were consistent with their biological indexes in some extent.

  2. Social Cognition in Individuals at Ultra-High Risk for Psychosis: A Meta-Analysis.

    Directory of Open Access Journals (Sweden)

    R J M van Donkersgoed

    Full Text Available Treatment in the ultra-high risk stage for a psychotic episode is critical to the course of symptoms. Markers for the development of psychosis have been studied, to optimize the detection of people at risk of psychosis. One possible marker for the transition to psychosis is social cognition. To estimate effect sizes for social cognition based on a quantitative integration of the published evidence, we conducted a meta-analysis of social cognitive performance in people at ultra high risk (UHR.A literature search (1970-July 2015 was performed in PubMed, PsychINFO, Medline, Embase, and ISI Web of Science, using the search terms 'social cognition', 'theory of mind', 'emotion recognition', 'attributional style', 'social knowledge', 'social perception', 'empathy', 'at risk mental state', 'clinical high risk', 'psychosis prodrome', and 'ultra high risk'. The pooled effect size (Cohen's D and the effect sizes for each domain of social cognition were calculated. A random effects model with 95% confidence intervals was used.Seventeen studies were included in the analysis. The overall significant effect was of medium magnitude (d = 0.52, 95% Cl = 0.38-0.65. No moderator effects were found for age, gender and sample size. Sub-analyses demonstrated that individuals in the UHR phase show significant moderate deficits in affect recognition and affect discrimination in faces as well as in voices and in verbal Theory of Mind (TOM. Due to an insufficient amount of studies, we did not calculate an effect size for attributional bias and social perception/ knowledge. A majority of studies did not find a correlation between social cognition deficits and transition to psychosis, which may suggest that social cognition in general is not a useful marker for the development of psychosis. However some studies suggest the possible predictive value of verbal TOM and the recognition of specific emotions in faces for the transition into psychosis. More research is needed on

  3. Social Cognition in Individuals at Ultra-High Risk for Psychosis: A Meta-Analysis

    Science.gov (United States)

    van Donkersgoed, R. J. M.; Wunderink, L.; Nieboer, R.; Aleman, A.; Pijnenborg, G. H. M.

    2015-01-01

    Objective Treatment in the ultra-high risk stage for a psychotic episode is critical to the course of symptoms. Markers for the development of psychosis have been studied, to optimize the detection of people at risk of psychosis. One possible marker for the transition to psychosis is social cognition. To estimate effect sizes for social cognition based on a quantitative integration of the published evidence, we conducted a meta-analysis of social cognitive performance in people at ultra high risk (UHR). Methods A literature search (1970-July 2015) was performed in PubMed, PsychINFO, Medline, Embase, and ISI Web of Science, using the search terms ‘social cognition’, ‘theory of mind’, ‘emotion recognition’, ‘attributional style’, ‘social knowledge’, ‘social perception’, ‘empathy’, ‘at risk mental state’, ‘clinical high risk’, ‘psychosis prodrome’, and ‘ultra high risk’. The pooled effect size (Cohen’s D) and the effect sizes for each domain of social cognition were calculated. A random effects model with 95% confidence intervals was used. Results Seventeen studies were included in the analysis. The overall significant effect was of medium magnitude (d = 0.52, 95% Cl = 0.38–0.65). No moderator effects were found for age, gender and sample size. Sub-analyses demonstrated that individuals in the UHR phase show significant moderate deficits in affect recognition and affect discrimination in faces as well as in voices and in verbal Theory of Mind (TOM). Due to an insufficient amount of studies, we did not calculate an effect size for attributional bias and social perception/ knowledge. A majority of studies did not find a correlation between social cognition deficits and transition to psychosis, which may suggest that social cognition in general is not a useful marker for the development of psychosis. However some studies suggest the possible predictive value of verbal TOM and the recognition of specific emotions in faces

  4. Long-Range Electron Effects upon Irradiation of Molecular Solids and Polymers

    International Nuclear Information System (INIS)

    Feldman, V.I.

    2006-01-01

    Long-range electron effects are responsible for specific localization and selectivity of the radiation-induced chemical transformations occurring in molecular solids and polymers, when the classic diffusion mobility is essentially restricted. In particullar, understanding of the effects of this kind may be of key significance for establishing new ways to control the radiation sensitivity of macromolecules and organized polymeric systems, nanomaterials and biopolymers. This talk will present an overview of model studies of the long-range electron effects with the characteristic scale from several angstroms to ten nanometers. The following aspects of the problem will be analyzed: (1) Positive hole delocalization in ionized molecules. This phenomenon has been demonstrated experimentally and confirmed by quantum chemical calculations for a number of various-type molecules (alkanes, conjugated polyenes, bifunctional compounds). The effective delocalization length was found to be up to 2 nm (or even larger). The role of this effect in site-selective radiation chemistry will be discussed in the frame of concepts of distributed reactivity and 'switching' between delocalized and localized states. (2) Trap-to-trap positive hole and electron migration between isolated molecules or functional groups. The characteristic distance for this process was estimated to be 2 to 4 nm. Special impact will be made on the possible role of this process in selection of specific isomers or conformers upon irradiation of complex systems and macromolecules. (3) The effects of long-range scavenging of low-energy secondary electrons in polymers and organized polymeric systems. As revealed by model experiments, the radius of electron capture in solid polymers may be in the range of 1 to 10 nm. Possible implications of scavenging effects for controlling the radiation chemistry of polymers and organized polymeric systems will be considered

  5. Effect of an 8K ultra-high-definition television system in a case of laparoscopic gynecologic surgery.

    Science.gov (United States)

    Aoki, Yoichi; Matsuura, Masahiko; Chiba, Toshio; Yamashita, Hiromasa

    2017-09-01

    Various endoscopic devices have been developed for advanced minimally invasive surgery. We recently applied a new 8K ultra-high-definition television system during laparoscopic treatment of endometriosis. The procedure, which is described in detail, stands as the first reported application of an 8K ultra-high-definition system for laparoscopic gynecologic surgery. Comparison is made between depiction of the lesion by the new system and depiction by a full high-definition system. Improved diagnostic accuracy resulted from the increased image resolution, and we believe that this and other advantages will lead to widespread acceptance and further application of 8K ultra-high-definition systems in the field of gynecologic surgery.

  6. Consideration of ultra-high temperature nuclear heat sources for MHD conversion systems

    International Nuclear Information System (INIS)

    Holman, R.R.; Tobin, J.M.; Young, W.E.

    1975-01-01

    The nuclear technology reactors developed and tested in the Nuclear Engine Rocket Vehicle Application (NERVA) program operated with fuel exit gas temperatures in excess of 2600 K. This experience provided a significant ultra-high temperature technology base and design insight for commercial power applications. Design approaches to accommodate fission product retention and other key prevailing requirements are examined in view of the basic overriding functional requirements, and some interesting reconsiderations are suggested. Predicted overall system performance potentials for a 2000 K MHD conversion system and reactor parameter requirements are compared and related to existing technology status. Needed verification and development efforts are suggested. A reconsideration of basic design approaches is suggested that could open the door for immediate development of ultrahigh temperature nuclear heat sources for advanced energy systems

  7. Monte Carlo simulations of ultra high vacuum and synchrotron radiation for particle accelerators

    CERN Document Server

    AUTHOR|(CDS)2082330; Leonid, Rivkin

    With preparation of Hi-Lumi LHC fully underway, and the FCC machines under study, accelerators will reach unprecedented energies and along with it very large amount of synchrotron radiation (SR). This will desorb photoelectrons and molecules from accelerator walls, which contribute to electron cloud buildup and increase the residual pressure - both effects reducing the beam lifetime. In current accelerators these two effects are among the principal limiting factors, therefore precise calculation of synchrotron radiation and pressure properties are very important, desirably in the early design phase. This PhD project shows the modernization and a major upgrade of two codes, Molflow and Synrad, originally written by R. Kersevan in the 1990s, which are based on the test-particle Monte Carlo method and allow ultra-high vacuum and synchrotron radiation calculations. The new versions contain new physics, and are built as an all-in-one package - available to the public. Existing vacuum calculation methods are overvi...

  8. Ultra-high-throughput screening method for the directed evolution of glucose oxidase.

    Science.gov (United States)

    Ostafe, Raluca; Prodanovic, Radivoje; Nazor, Jovana; Fischer, Rainer

    2014-03-20

    Glucose oxidase (GOx) is used in many industrial processes that could benefit from improved versions of the enzyme. Some improvements like higher activity under physiological conditions and thermal stability could be useful for GOx applications in biosensors and biofuel cells. Directed evolution is one of the currently available methods to engineer improved GOx variants. Here, we describe an ultra-high-throughput screening system for sorting the best enzyme variants generated by directed evolution that incorporates several methodological refinements: flow cytometry, in vitro compartmentalization, yeast surface display, fluorescent labeling of the expressed enzyme, delivery of glucose substrate to the reaction mixture through the oil phase, and covalent labeling of the cells with fluorescein-tyramide. The method enables quantitative screening of gene libraries to identify clones with improved activity and it also allows cells to be selected based not only on the overall activity but also on the specific activity of the enzyme. Copyright © 2014 Elsevier Ltd. All rights reserved.

  9. submitter Projects for ultra-high-energy circular colliders at CERN

    CERN Document Server

    Bogomyagkov, A V; Levichev, E B; Piminov, P A; Sinyatkin, S V; Shatilov, D N; Benedict, M; Oide, K; Zimmermann, F

    2016-01-01

    Within the Future Circular Collider (FCC) design study launched at CERN in 2014, it is envisaged to construct hadron (FCC-hh) and lepton (FCC-ee) ultra-high-energy machines aimed to replace the LHC upon the conclusion of its research program. The Budker Institute of Nuclear Physics is actively involved in the development of the FCC-ee electron–positron collider. The Crab Waist (CR) scheme of the collision region that has been proposed by INP and will be implemented at FCC-ee is expected to provide high luminosity over a broad energy range. The status and development of the FCC project are described, and its parameters and limitations are discussed for the lepton collider in particular.

  10. Bursts of the Crab Nebula gamma-ray emission at high and ultra-high energies

    Directory of Open Access Journals (Sweden)

    Lidvansky A.S.

    2017-01-01

    Full Text Available Characteristics of the flares of gamma rays detected from the Crab Nebula by the AGILE and Fermi-LAT satellite instruments are compared with those of a gamma ray burst recorded by several air shower arrays on February 23, 1989 and with one recent observation made by the ARGO-YBJ array. It is demonstrated that though pulsar-periodicity and energy spectra of emissions at 100 MeV (satellite gamma ray telescopes and 100 TeV (EAS arrays are different, their time structures seem to be similar. Moreover, maybe the difference between “flares” and “waves” recently found in the Crab Nebula emission by the AGILE team also exists at ultra-high energies.

  11. Weld Metallurgy and Mechanical Properties of High Manganese Ultra-high Strength Steel Dissimilar Welds

    Science.gov (United States)

    Dahmen, Martin; Lindner, Stefan; Monfort, Damien; Petring, Dirk

    The increasing demand for ultra-high strength steels in vehicle manufacturing leads to the application of new alloys. This poses a challenge on joining especially by fusion welding. A stainless high manganese steel sheet with excellent strength and deformation properties stands in the centre of the development. Similar and dissimilar welds with a metastable austenitic steel and a hot formed martensitic stainless steel were performed. An investigation of the mixing effects on the local microstructure and the hardness delivers the metallurgical features of the welds. Despite of carbon contents above 0.4 wt.% none of the welds have shown cracks. Mechanical properties drawn from tensile tests deliver high breaking forces enabling a high stiffness of the joints. The results show the potential for the application of laser beam welding for joining in assembly of structural parts.

  12. Ultra-High Gradient S-band Linac for Laboratory and Industrial Applications

    Science.gov (United States)

    Faillace, L.; Agustsson, R.; Dolgashev, V.; Frigola, P.; Murokh, A.; Rosenzweig, J.; Yakimenko, V.

    2010-11-01

    A strong demand for high gradient structures arises from the limited real estate available for linear accelerators. RadiaBeam Technologies is developing a Doubled Energy Compact Accelerator (DECA) structure: an S-band standing wave electron linac designed to operate at accelerating gradients of up to 50 MV/m. In this paper, we present the radio-frequency design of the DECA S-band accelerating structure, operating at 2.856 GHz in the π-mode. The structure design is heavily influenced by NLC collaboration experience with ultra high gradient X-band structures; S-band, however, is chosen to take advantage of commonly available high power S-band klystrons.

  13. Low temperature growth of ultra-high mass density carbon nanotube forests on conductive supports

    International Nuclear Information System (INIS)

    Sugime, Hisashi; Esconjauregui, Santiago; Yang, Junwei; D'Arsié, Lorenzo; Robertson, John; Oliver, Rachel A.; Bhardwaj, Sunil; Cepek, Cinzia

    2013-01-01

    We grow ultra-high mass density carbon nanotube forests at 450 °C on Ti-coated Cu supports using Co-Mo co-catalyst. X-ray photoelectron spectroscopy shows Mo strongly interacts with Ti and Co, suppressing both aggregation and lifting off of Co particles and, thus, promoting the root growth mechanism. The forests average a height of 0.38 μm and a mass density of 1.6 g cm −3 . This mass density is the highest reported so far, even at higher temperatures or on insulators. The forests and Cu supports show ohmic conductivity (lowest resistance ∼22 kΩ), suggesting Co-Mo is useful for applications requiring forest growth on conductors

  14. High-efficiency water-loaded microwave antenna in ultra-high-frequency band

    Science.gov (United States)

    Gong, Zilun; Bartone, Chris; Yang, Fuyi; Yao, Jie

    2018-03-01

    High-index dielectrics are widely used in microwave antennas to control the radiation characteristics. Liquid water, with a high dielectric index at microwave frequency, is an interesting material to achieving tunable functionalities. Here, we demonstrate a water-loaded microwave antenna system that has high loss-tolerance and wideband tunability enabled by fluidity. Our simulation and experimental results show that the resonance frequency can be effectively tuned by the size of loading water. Furthermore, the antenna systems with water loading can achieve high radiation efficiency (>90%) in the ultra-high-frequency (0.3-3 GHz) band. This work brings about opportunities in realistic tunable microwave antenna designs enabled by liquid.

  15. Application of Ultra High Pressure Cavitation Peening to Prevent PWSCC on Primary Plant Components

    Energy Technology Data Exchange (ETDEWEB)

    Poling, G.R.

    2015-07-01

    Primary Water Stress Corrosion Cracking (PWSCC) on Alloy 600/82/182 susceptible materials can lead to increased costs for maintenance and repair/replacement activities on nuclear power plant primary components. A process called Ultra High Pressure (UHP) cavitation peening can be safely and cost effectively applied to the susceptible materials to generate compressive stresses on the surface and prevent PWSCC initiation. AREVA has developed the tooling systems to apply the UHP cavitation peening process on reactor vessel head penetration nozzles, bottom mounted nozzles and primary nozzles. Applying the UHP cavitation peening process before PWSCC initiation will prevent future repairs/replacements, reduce maintenance costs, and provide more effective on-time for the reactor. (Author)

  16. Ultra high energy cosmic rays: clustering, GUT scale and neutrino masses

    International Nuclear Information System (INIS)

    Fodor, Z.

    2002-01-01

    The clustering of ultra high energy (above 5 · 10 19 eV) cosmic rays (UHECR) suggests that they might be emitted by compact sources. We present a statistical analysis on the source density based on the multiplicities. The propagation of UHECR protons is studied in detail. The UHECR spectrum is consistent with the decay of GUT scale particles and/or with the Z-burst. The predicted GUT mass is m x = 10 b GeV, where b 14.6 -1.7 +1.6 . Our neutrino mass prediction depends on the origin of the power part of the spectrum: m ν = 2.75 -0.97 +1.28 eV for halo and 0.26 -0.14 +0.20 eV for extragalactic (EG) origin

  17. Determining the Environmental Benefits of Ultra High Performance Concrete as a Bridge Construction Material

    Science.gov (United States)

    Lande Larsen, Ingrid; Granseth Aasbakken, Ida; O'Born, Reyn; Vertes, Katalin; Terje Thorstensen, Rein

    2017-10-01

    Ultra High Performance Concrete (UHPC) is a material that is attracting attention in the construction industry due to the high mechanical strength and durability, leading to structures having low maintenance requirements. The production of UHPC, however, has generally higher environmental impact than normal strength concrete due to the increased demand of cement required in the concrete mix. What is still not sufficiently investigated, is if the longer lifetime, slimmer construction and lower maintenance requirements lead to a net environmental benefit compared to standard concrete bridge design. This study utilizes life cycle assessment (LCA) to determine the lifetime impacts of two comparable highway crossing footbridges spanning 40 meters, designed respectively with UHPC and normal strength concrete. The results of the study show that UHPC is an effective material for reducing lifetime emissions from construction and maintenance of long lasting infrastructure, as the UHPC design outperforms the normal strength concrete bridge in most impact categories.

  18. Ultra-high-resolution alpha spectrometry for nuclear forensics and safeguards applications

    International Nuclear Information System (INIS)

    Bacrania, Minesh K.; Croce, Mark; Bond, Evelyn; Dry, Donald; Moody, W. Allen; Lamont, Stephen; Rabin, Michael; Rim, Jung; Smith, Audrey; Beall, James; Bennett, Douglas; Kotsubo, Vincent; Horansky, Robert; Hilton, Gene; Schmidt, Daniel; Ullom, Joel; Cantor, Robin

    2010-01-01

    We will present our work on the development of ultra-high-resolution detectors for alpha particle spectrometry. These detectors, based on superconducting transition-edge sensors, offer energy resolution that is five to ten times better than conventional silicon detectors. Using these microcalorimeter detectors, the isotopic composition of mixed-actinide samples can be determined rapidly without the need for actinide separation chemistry to isolate each element, or mass spectrometry to separate isotopic signatures that can not be resolved using traditional alpha spectrometry (e.g. Pu-239/Pu-240, or Pu-238/Am-241). This paper will cover the detector and measurement system, actinide source preparation, and the quantitative isotopic analysis of a number of forensics- and safeguards-relevant radioactive sources.

  19. CGLXTouch: A multi-user multi-touch approach for ultra-high-resolution collaborative workspaces

    KAUST Repository

    Ponto, Kevin

    2011-06-01

    This paper presents an approach for empowering collaborative workspaces through ultra-high resolution tiled display environments concurrently interfaced with multiple multi-touch devices. Multi-touch table devices are supported along with portable multi-touch tablet and phone devices, which can be added to and removed from the system on the fly. Events from these devices are tagged with a device identifier and are synchronized with the distributed display environment, enabling multi-user support. As many portable devices are not equipped to render content directly, a remotely scene is streamed in. The presented approach scales for large numbers of devices, providing access to a multitude of hands-on techniques for collaborative data analysis. © 2011 Elsevier B.V. All rights reserved.

  20. Telescope Array Radar (TARA) observatory for Ultra-High Energy Cosmic Rays

    Energy Technology Data Exchange (ETDEWEB)

    Abbasi, R.; Othman, M. Abou Bakr [University of Utah, 115 S 1400 E #201 JFB, Salt Lake City, UT 84112 (United States); Allen, C. [University of Kansas, Lawrence, KS 66045 (United States); Beard, L. [Purdue University, West Lafayette, IN 47907 (United States); Belz, J. [University of Utah, 115 S 1400 E #201 JFB, Salt Lake City, UT 84112 (United States); Besson, D. [University of Kansas, Lawrence, KS 66045 (United States); Moscow Engineering and Physics Institute, 31 Kashirskaya Shosse, Moscow 115409 (Russian Federation); Byrne, M.; Farhang-Boroujeny, B.; Gardner, A. [University of Utah, 115 S 1400 E #201 JFB, Salt Lake City, UT 84112 (United States); Gillman, W.H. [Gillman and Associates, Salt Lake City, UT 84106 (United States); Hanlon, W. [University of Utah, 115 S 1400 E #201 JFB, Salt Lake City, UT 84112 (United States); Hanson, J. [University of Kansas, Lawrence, KS 66045 (United States); Jayanthmurthy, C. [University of Utah, 115 S 1400 E #201 JFB, Salt Lake City, UT 84112 (United States); Kunwar, S. [University of Kansas, Lawrence, KS 66045 (United States); Larson, S.L. [Utah State University, Logan, Utah 84322 (United States); Myers, I., E-mail: isaac@cosmic.utah.edu [University of Utah, 115 S 1400 E #201 JFB, Salt Lake City, UT 84112 (United States); Prohira, S.; Ratzlaff, K. [University of Kansas, Lawrence, KS 66045 (United States); Sokolsky, P. [University of Utah, 115 S 1400 E #201 JFB, Salt Lake City, UT 84112 (United States); Takai, H. [Brookhaven National Laboratory, Upton, NY 11973 (United States); and others

    2014-12-11

    Construction was completed during summer 2013 on the Telescope Array RAdar (TARA) bi-static radar observatory for Ultra-High Energy Cosmic Rays (UHECR). TARA is co-located with the Telescope Array, the largest “conventional” cosmic ray detector in the Northern Hemisphere, in radio-quiet Western Utah. TARA employs an 8 MW Effective Radiated Power (ERP) VHF transmitter and smart receiver system based on a 250 MS/s data acquisition system in an effort to detect the scatter of sounding radiation by UHECR-induced atmospheric ionization. TARA seeks to demonstrate bi-static radar as a useful new remote sensing technique for UHECRs. In this report, we describe the design and performance of the TARA transmitter and receiver systems.

  1. Influence of Carbide Modifications on the Mechanical Properties of Ultra-High-Strength Stainless Steels

    Science.gov (United States)

    Seo, Joo-Young; Park, Soo-Keun; Kwon, Hoon; Cho, Ki-Sub

    2017-10-01

    The mechanical properties of ultra-high-strength secondary hardened stainless steels with varying Co, V, and C contents have been studied. A reduced-Co alloy based on the chemical composition of Ferrium S53 was made by increasing the V and C content. This changed the M2C-strengthened microstructure to a MC plus M2C-strengthened microstructure, and no deteriorative effects were observed for peak-aged and over-aged samples despite the large reduction in Co content from 14 to 7 wt pct. The mechanical properties according to alloying modification were associated with carbide precipitation kinetics, which was clearly outlined by combining analytical tools including small-angle neutron scattering (SANS) as well as an analytical TEM with computational simulation.

  2. Ultra-high vacuum compatible optical chopper system for synchrotron x-ray scanning tunneling microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Hao, E-mail: hc000211@ohio.edu [Advanced Photon Source, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, Illinois 60439 (United States); Nanoscale and Quantum Phenomena Institute, Physics & Astronomy Department, Ohio University, Athens, Ohio 45701 (United States); Cummings, Marvin; Shirato, Nozomi; Stripe, Benjamin; Preissner, Curt; Freeland, John W. [Advanced Photon Source, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, Illinois 60439 (United States); Rosenmann, Daniel [Center for Nanoscale Materials, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, Illinois 60439 (United States); Kersell, Heath; Hla, Saw-Wai [Nanoscale and Quantum Phenomena Institute, Physics & Astronomy Department, Ohio University, Athens, Ohio 45701 (United States); Center for Nanoscale Materials, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, Illinois 60439 (United States); Rose, Volker, E-mail: vrose@anl.gov [Advanced Photon Source, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, Illinois 60439 (United States); Center for Nanoscale Materials, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, Illinois 60439 (United States)

    2016-01-28

    High-speed beam choppers are a crucial part of time-resolved x-ray studies as well as a necessary component to enable elemental contrast in synchrotron x-ray scanning tunneling microscopy (SX-STM). However, many chopper systems are not capable of operation in vacuum, which restricts their application to x-ray studies with high photon energies, where air absorption does not present a significant problem. To overcome this limitation, we present a fully ultra-high vacuum (UHV) compatible chopper system capable of operating at variable chopping frequencies up to 4 kHz. The lightweight aluminum chopper disk is coated with Ti and Au films to provide the required beam attenuation for soft and hard x-rays with photon energies up to about 12 keV. The chopper is used for lock-in detection of x-ray enhanced signals in SX-STM.

  3. Selection and evaluation of an ultra high vacuum gate valve for Isabelle beam line vacuum system

    International Nuclear Information System (INIS)

    Foerster, C.L.; McCafferty, D.

    1980-01-01

    A minimum of eighty-four (84) Ultra High Vacuum Gate Valves will be utilized in ISABELLE to protect proton beam lines from catastrophic vacuum failure and to provide sector isolation for maintenance requirements. The valve to be selected must function at less than 1 x 10 -11 Torr pressure and be bakeable to 300 0 C in its open or closed position. In the open position, the valve must have an RF shield to make the beam line walls appear continuous. Several proposed designs were built and evaluated. The evaluation consisted mainly of leak testing, life tests, thermal cycling, mass spectrometer analysis, and 10 -12 Torr operation. Problems with initial design and fabrication were resolved. Special requirements for design and construction were developed. This paper describes the tests on two final prototypes which appear to be the best candidates for ISABELLE operation

  4. Pressure measurements in the AGS Booster ultra-high vacuum system

    International Nuclear Information System (INIS)

    Gabusi, J.; Geller, J.; Hseuh, H.C.; Mapes, M.; Stattel, P.

    1992-01-01

    An average pressure of mid 10 -11 Torr has been achieved and maintained in the AGS Booster ring vacuum system during its first year of operation. This ultra-high vacuum system is monitored through remote controlled Bayard-Alpert Gauges (BAGs). The characteristics of the pressure measurements with BAGs over the long cable lengths (up to 200 m) and under various accelerator operating conditions will be described. Two types of noise in the pressure readouts have been identified; the electromagnetic interference (EMI) associated with the acceleration cycles of the Booster and the environment noise associated with the temperature of the collector cables. The magnitude of the noise pickup depends on the routing of the collector cables and reaches the equivalent pressure of low 10 -9 Torr

  5. Development and data analysis of a radio-detection of ultra high energy cosmic rays experiment

    International Nuclear Information System (INIS)

    Belletoile, A.

    2007-10-01

    The radio-detection of cosmic rays was first attempted in the sixties. Unfortunately at that time, the results suffered from poor reproducibility and the technique was abandoned in favour of direct particle and fluorescence detection. Taking advantage of recent technological improvements the radio-detection of ultra high energy cosmic rays is being reinvestigated. In this document, first, we remind the reader of the global problematic of cosmic rays. Then, the several mechanisms involved in the emission of an electric field associated with extensive air showers are discussed. The CODALEMA (cosmic detection array with logarithmic electro magnetic antenna) experiment that aims to demonstrate the feasibility of cosmic ray radio-detection, is extensively described along with the first experimental results. A radio-detection test experiment implanted at the giant detector Pierre Auger is presented. It should provide inputs to design the future detector using this technique at extreme energies. (author)

  6. The clinical potential of ultra-high-speed echo-planar imaging

    International Nuclear Information System (INIS)

    Worthington, B.S.; Firth, J.L.; Morris, G.K.; Johnson, I.R.; Coxon, R.; Blamire, A.M.; Gibbs, P.; Mansfield, P.

    1990-01-01

    Ultra-high-speed echo-planar imaging (EPI) allows acquisition of a complete two-dimensional image in 64 to 128 ms devoid of movement artefact and without sacrifice of contrast due to relaxation time effects. In conventional whole-body MRI, however, obtrusive movement artefact and extended imaging time, resulting from the need to apply multiple sequences to facilitate lesion detection and pathological characterization, remain limitations. Reduced total examination time increases patient tolerance and throughput; furthermore optimization of contrast to achieve maximal conspicuity of particular features in liver or brain pathology is achieved simply and interactively by real time adjustment of the imaging parameters. The method provides the opportunity to study in real time dynamic events such as flow phenomena in the vascular and cerebrospinal fluid compartments of the brain as well as the kinetics of administered contrast agents. EPI is the only means of capturing the irregular motion of aperiodic cardiac events and bowel peristalsis. (author)

  7. Graphene electric double layer capacitor with ultra-high-power performance

    International Nuclear Information System (INIS)

    Miller, John R.; Outlaw, R.A.; Holloway, B.C.

    2011-01-01

    We have demonstrated, for the first time, efficient 120 Hz filtering by an electric double layer capacitor (EDLC). The key to this ultra-high-power performance is electrodes made from vertically oriented graphene nanosheets grown directly on metal current collectors. This design minimized both electronic and ionic resistance and produced capacitors having RC time-constants of less than 200 μs. Significantly, graphene nanosheets have a preponderance of exposed edge planes that greatly increase stored charge over designs relying on basal plane surfaces. Collectively these factors make vertically oriented graphene nanosheet electrodes ideally suited for producing high-frequency EDLCs. Capacitors constructed with these electrodes are predicted to be significantly smaller than aluminum electrolyte capacitors that they could functionally replace plus be manufactured using standard semiconductor process equipment, creating interesting commercial opportunities.

  8. Development of filter element from nanocomposites of ultra high molar mass polyethylene having silver nanoparticles

    International Nuclear Information System (INIS)

    Bizzo, Maurizio A.; Wang, S. Hui

    2015-01-01

    The production of polymer based filter elements for water is widespread in the market but has an undesirable characteristic, they are not always efficient and capable of retaining or eliminating microorganisms. This paper proposes the production of filters with biocidal activity, comprised by nanocomposites of ultra-high molar mass polyethylene (UHMMPE) containing silver nanoparticles. The polymer is responsible for the uniform porous structure of the filter element and the Ag nanoparticles for its biocidal action. The filter elements were produced from two kinds of UHMMPE particles with different particle size distributions, one in the range of 150 to 200μm and the other of 300 to 400μm. Samples were collected from the obtained filter elements and characterized by X-ray diffractometry, scanning electron microscopy and microanalysis. The results indicated the formation of nanocomposite containing silver nanoparticles. (author)

  9. Quantification of sulphur amino acids by ultra-high performance liquid chromatography in aquatic invertebrates.

    Science.gov (United States)

    Thera, Jennifer C; Kidd, Karen A; Dodge-Lynch, M Elaine; Bertolo, Robert F

    2017-12-15

    We examined the performance of an ultra-high performance liquid chromatography method to quantify protein-bound sulphur amino acids in zooplankton. Both cysteic acid and methionine sulfone were linear from 5 to 250 pmol (r 2  = 0.99), with a method detection limit of 13 pmol and 9 pmol, respectively. Although there was no matrix effect on linearity, adjacent peaks and co-eluting noise from the invertebrate proteins increased the detection limits when compared to common standards. Overall, performance characteristics were reproducible and accurate, and provide a means for quantifying sulphur amino acids in aquatic invertebrates, an understudied group. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Porous carbon with small mesoporesas an ultra-high capacity adsorption medium

    Science.gov (United States)

    Gao, Biaofeng; Zhou, Haitao; Chen, De; Yang, Jianhong

    2017-10-01

    Resins (732-type), abundant and inexpensive resources were used to prepare porous carbon with small mesopores (CSM) by carbonization and post-chemical-activation with potassium hydroxide (KOH). The N2 adsorption measurements revealed that CSM had high surface areas (1776.5 m2 g-1), large pore volumes (1.10 cm3 g-1), and nearly optimal narrow small mesopore sizes ranging from 2 to 7 nm. CSM was used as adsorbent to investigate the adsorption behavior for Rhodamine B (RhB). Due to the optimal pore size distributions (PSD), intensive-stacking interaction, S-doped, and electrostatic attraction, the CSM exhibited an ultra-high-capacity of 1590 mg g-1 for RhB in aqueous solutions.

  11. Telescope Array Radar (TARA) observatory for Ultra-High Energy Cosmic Rays

    International Nuclear Information System (INIS)

    Abbasi, R.; Othman, M. Abou Bakr; Allen, C.; Beard, L.; Belz, J.; Besson, D.; Byrne, M.; Farhang-Boroujeny, B.; Gardner, A.; Gillman, W.H.; Hanlon, W.; Hanson, J.; Jayanthmurthy, C.; Kunwar, S.; Larson, S.L.; Myers, I.; Prohira, S.; Ratzlaff, K.; Sokolsky, P.; Takai, H.

    2014-01-01

    Construction was completed during summer 2013 on the Telescope Array RAdar (TARA) bi-static radar observatory for Ultra-High Energy Cosmic Rays (UHECR). TARA is co-located with the Telescope Array, the largest “conventional” cosmic ray detector in the Northern Hemisphere, in radio-quiet Western Utah. TARA employs an 8 MW Effective Radiated Power (ERP) VHF transmitter and smart receiver system based on a 250 MS/s data acquisition system in an effort to detect the scatter of sounding radiation by UHECR-induced atmospheric ionization. TARA seeks to demonstrate bi-static radar as a useful new remote sensing technique for UHECRs. In this report, we describe the design and performance of the TARA transmitter and receiver systems

  12. Ultra High Electrical Performance of Nano Nickel Oxide and Polyaniline Composite Materials

    Directory of Open Access Journals (Sweden)

    Xiaomin Cai

    2017-07-01

    Full Text Available The cooperative effects between the PANI (polyaniline/nano-NiO (nano nickel oxide composite electrode material and redox electrolytes (potassium iodide, KI for supercapacitor applications was firstly discussed in this article, providing a novel method to prepare nano-NiO by using β-cyelodextrin (β-CD as the template agent. The experimental results revealed that the composite electrode processed a high specific capacitance (2122.75 F·g−1 at 0.1 A·g−1 in 0.05 M KI electrolyte solution, superior energy density (64.05 Wh·kg−1 at 0.2 A·g−1 in the two-electrode system and excellent cycle performance (86% capacitance retention after 1000 cycles at 1.5 A·g−1. All those ultra-high electrical performances owe to the KI active material in the electrolyte and the PANI coated nano-NiO structure.

  13. APPLICATION OF ULTRA-HIGH PERFORMANCE CONCRETE TO PEDESTRIAN CABLE-STAYED BRIDGES

    Directory of Open Access Journals (Sweden)

    CHI-DONG LEE

    2013-06-01

    Full Text Available The use of ultra-high performance concrete (UHPC, which enables reducing the cross sectional dimension of the structures due to its high strength, is expected in the construction of the super-long span bridges. Unlike conventional concrete, UHPC experiences less variation of material properties such as creep and drying shrinkage and can reduce uncertainties in predicting time-dependent behavior over the long term. This study describes UHPC’s material characteristics and benefits when applied to super-long span bridges. A UHPC girder pedestrian cable-stayed bridge was designed and successfully constructed. The UHPC reduced the deflections in both the short and long term. The cost analysis demonstrates a highly competitive price for UHPC. This study indicates that UHPC has a strong potential for application in the super-long span bridges.

  14. The MIDAS telescope for microwave detection of ultra-high energy cosmic rays

    Science.gov (United States)

    Alvarez-Muñiz, J.; Amaral Soares, E.; Berlin, A.; Bogdan, M.; Boháčová, M.; Bonifazi, C.; Carvalho, W. R.; de Mello Neto, J. R. T.; Facal San Luis, P.; Genat, J. F.; Hollon, N.; Mills, E.; Monasor, M.; Privitera, P.; Ramos de Castro, A.; Reyes, L. C.; Richardson, M.; Rouille d'Orfeuil, B.; Santos, E. M.; Wayne, S.; Williams, C.; Zas, E.; Zhou, J.

    2013-08-01

    We present the design, implementation and data taking performance of the MIcrowave Detection of Air Showers (MIDAS) experiment, a large field of view imaging telescope designed to detect microwave radiation from extensive air showers induced by ultra-high energy cosmic rays. This novel technique may bring a tenfold increase in detector duty cycle when compared to the standard fluorescence technique based on detection of ultraviolet photons. The MIDAS telescope consists of a 4.5 m diameter dish with a 53-pixel receiver camera, instrumented with feed horns operating in the commercial extended C-Band (3.4-4.2 GHz). A self-trigger capability is implemented in the digital electronics. The main objectives of this first prototype of the MIDAS telescope - to validate the telescope design, and to demonstrate a large detector duty cycle - were successfully accomplished in a dedicated data taking run at the University of Chicago campus prior to installation at the Pierre Auger Observatory.

  15. The MIDAS experiment: A prototype for the microwave emission of Ultra-High Energy Cosmic Rays

    International Nuclear Information System (INIS)

    Monasor, M.; Alekotte, I.; Alvarez-Muniz, J.; Berlin, A.; Bertou, X.; Bodgan, M.; Bohacova, M.; Bonifazi, C.; Carvalho, W.; Mello Neto, J.R.T. de; Genat, J.F.; Facal San Luis, P.; Mills, E.; Rouille d'Orfeuil, B.; Wayne, S.; Reyes, L.C.; Santos, E.M.; Privitera, P.; Williams, C.; Zas, E.

    2011-01-01

    Recent measurements suggest that extensive air showers initiated by ultra-high energy cosmic rays (UHECR) emit signals in the microwave band of the electromagnetic spectrum caused by the collisions of the free-electrons with the atmospheric neutral molecules in the plasma produced by the passage of the shower. Such emission is isotropic and could allow the detection of air showers with 100% duty cycle and a calorimetric-like energy measurement, a significant improvement over current detection techniques. We have built MIDAS (MIcrowave Detection of Air Showers), a prototype of microwave detector, which consists of a 4.5 m diameter antenna with a cluster of 53 feed-horns in the 4 GHz range. The details of the prototype and first results will be presented.

  16. Calibration of ultra-high frequency (UHF) partial discharge sensors using FDTD method

    Science.gov (United States)

    Ishak, Asnor Mazuan; Ishak, Mohd Taufiq

    2018-02-01

    Ultra-high frequency (UHF) partial discharge sensors are widely used for conditioning monitoring and defect location in insulation system of high voltage equipment. Designing sensors for specific applications often requires an iterative process of manufacturing, testing and mechanical modifications. This paper demonstrates the use of finite-difference time-domain (FDTD) technique as a tool to predict the frequency response of UHF PD sensors. Using this approach, the design process can be simplified and parametric studies can be conducted in order to assess the influence of component dimensions and material properties on the sensor response. The modelling approach is validated using gigahertz transverse electromagnetic (GTEM) calibration system. The use of a transient excitation source is particularly suitable for modeling using FDTD, which is able to simulate the step response output voltage of the sensor from which the frequency response is obtained using the same post-processing applied to the physical measurement.

  17. Ultra-high energy cosmic rays from white dwarf pulsars and the Hillas criterion

    International Nuclear Information System (INIS)

    Lobato, Ronaldo V.; Coelho, Jaziel G.; Malheiro, M.

    2017-01-01

    The origins of ultra-high-energy cosmic rays ( E ≳ 10 19 eV) are a mystery and still under debate in astroparticle physics. In recent years some efforts were made to understand their nature. In this contribution we consider the possibility of Some Soft Gamma Repeaters (SGRs) and Anomalous X-ray Pulsars (AXPs) beeing white dwarf pulsars, and show that these sources can achieve large electromagnetic potentials on their surface that accelerate particle almost at the speed of light, with energies E ∼ 10 20-21 eV. The sources SGRs/AXPs considered as highly magnetized white dwarfs are well described in the Hillas diagram, lying close to the AR Sorpii and AE Aquarii which are understood as white dwarf pulsars. (paper)

  18. Ultra-high aspect ratio replaceable AFM tips using deformation-suppressed focused ion beam milling

    International Nuclear Information System (INIS)

    Savenko, Alexey; Yildiz, Izzet; Petersen, Dirch Hjorth; Bøggild, Peter; Bartenwerfer, Malte; Krohs, Florian; Oliva, Maria; Harzendorf, Torsten

    2013-01-01

    Fabrication of ultra-high aspect ratio exchangeable and customizable tips for atomic force microscopy (AFM) using lateral focused ion beam (FIB) milling is presented. While on-axis FIB milling does allow high aspect ratio (HAR) AFM tips to be defined, lateral milling gives far better flexibility in terms of defining the shape and size of the tip. Due to beam-induced deformation, it has so far not been possible to define HAR structures using lateral FIB milling. In this work we obtain aspect ratios of up to 45, with tip diameters down to 9 nm, by a deformation-suppressing writing strategy. Several FIB milling strategies for obtaining sharper tips are discussed. Finally, assembly of the HAR tips on a custom-designed probe as well as the first AFM scanning is shown. (paper)

  19. On the reduced-complexity of LDPC decoders for ultra-high-speed optical transmission.

    Science.gov (United States)

    Djordjevic, Ivan B; Xu, Lei; Wang, Ting

    2010-10-25

    We propose two reduced-complexity (RC) LDPC decoders, which can be used in combination with large-girth LDPC codes to enable ultra-high-speed serial optical transmission. We show that optimally attenuated RC min-sum sum algorithm performs only 0.46 dB (at BER of 10(-9)) worse than conventional sum-product algorithm, while having lower storage memory requirements and much lower latency. We further study the use of RC LDPC decoding algorithms in multilevel coded modulation with coherent detection and show that with RC decoding algorithms we can achieve the net coding gain larger than 11 dB at BERs below 10(-9).

  20. A Novel Technique for Design of Ultra High Tunable Electrostatic Parallel Plate RF MEMS Variable Capacitor

    Science.gov (United States)

    Baghelani, Masoud; Ghavifekr, Habib Badri

    2017-12-01

    This paper introduces a novel method for designing of low actuation voltage, high tuning ratio electrostatic parallel plate RF MEMS variable capacitors. It is feasible to achieve ultra-high tuning ratios way beyond 1.5:1 barrier, imposed by pull-in effect, by the proposed method. The proposed method is based on spring strengthening of the structure just before the unstable region. Spring strengthening could be realized by embedding some dimples on the spring arms with the precise height. These dimples shorten the spring length when achieved to the substrate. By the proposed method, as high tuning ratios as 7.5:1 is attainable by only considering four dimple sets. The required actuation voltage for this high tuning ratio is 14.33 V which is simply achievable on-chip by charge pump circuits. Brownian noise effect is also discussed and mechanical natural frequency of the structure is calculated.

  1. Psychopathology and social functioning of 42 subjects from a Danish ultra high-risk cohort

    DEFF Research Database (Denmark)

    Madsen, Helle Karkov; Nordholm, Dorte; Krakauer, Kristine

    2017-01-01

    history of psychiatric disorders. Results: All UHR subjects met the criteria of at least 1 axis I diagnosis in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) and met on average four diagnoses (both axis I and II), mostly within the areas of depression, anxiety......Aim: To make a thorough characterization of the co-morbidity, psychopathology and demographics in the first Danish ultra high-risk (UHR) sample. Method: Forty-two UHR subjects went through comprehensive interviews assessing their psychopathology, psychiatric disorders, substance use and family...... and substance abuse. A total of 48% had schizotypal personality disorder and 19% had borderline personality disorder. Level of functioning was low with a mean score on the Social and Occupational Functioning Assessment Scale corresponding to "major impairment in several areas," and mean scores in the Global...

  2. The influence of the observatory latitude on the study of ultra high energy cosmic rays

    Energy Technology Data Exchange (ETDEWEB)

    Anjos, Rita C. dos [Departamento de Engenharias e Exatas, Universidade Federal do Paraná (UFPR), Pioneiro, 2153, Palotina, PR, 85950-000 Brazil (Brazil); De Souza, Vitor [Instituto de Física de São Carlos, Universidade de São Paulo, CP 369, São Carlos, SP, 13560-970 Brazil (Brazil); De Almeida, Rogerio M. [EEIMVR, Universidade Federal Fluminense, Volta Redonda, RJ (Brazil); Santos, Edivaldo M., E-mail: ritacassia@ufpr.br, E-mail: vitor@ifsc.usp.br, E-mail: rmenezes@id.uff.br, E-mail: emoura@if.usp.br [Instituto de Física, Universidade de São Paulo, Rua do Matão trav. R 187, São Paulo, 05508-090 Brazil (Brazil)

    2017-07-01

    Recent precision measurements of the Ultra High Energy Cosmic Rays (UHECR) arrival directions, spectrum and parameters related to the mass of the primary particle have been done by the HiRes, Pierre Auger and Telescope Array (TA) Observatories. In this paper, distributions of arrival directions of events in the nearby Universe are assumed to correlate with sources in the 2MASS Redshift Survey (2MRS), IRAS 1.2 Jy Survey, Palermo Swift-BAT and Swift-BAT catalogs, and the effect of the latitude of the observatory on the measurement of the energy spectrum and on the capability of measuring anisotropy is studied. The differences between given latitudes on the northern and southern hemispheres are quantified. It is shown that the latitude of the observatory: a) has an influence on the total flux measured and b) imposes an important limitation on the capability of measuring an anisotropic sky.

  3. Telescope Array Radar (TARA) observatory for Ultra-High Energy Cosmic Rays

    Science.gov (United States)

    Abbasi, R.; Othman, M. Abou Bakr; Allen, C.; Beard, L.; Belz, J.; Besson, D.; Byrne, M.; Farhang-Boroujeny, B.; Gardner, A.; Gillman, W. H.; Hanlon, W.; Hanson, J.; Jayanthmurthy, C.; Kunwar, S.; Larson, S. L.; Myers, I.; Prohira, S.; Ratzlaff, K.; Sokolsky, P.; Takai, H.; Thomson, G. B.; Von Maluski, D.

    2014-12-01

    Construction was completed during summer 2013 on the Telescope Array RAdar (TARA) bi-static radar observatory for Ultra-High Energy Cosmic Rays (UHECR). TARA is co-located with the Telescope Array, the largest "conventional" cosmic ray detector in the Northern Hemisphere, in radio-quiet Western Utah. TARA employs an 8 MW Effective Radiated Power (ERP) VHF transmitter and smart receiver system based on a 250 MS/s data acquisition system in an effort to detect the scatter of sounding radiation by UHECR-induced atmospheric ionization. TARA seeks to demonstrate bi-static radar as a useful new remote sensing technique for UHECRs. In this report, we describe the design and performance of the TARA transmitter and receiver systems.

  4. Ultra-high resolution optical coherence tomography for encapsulation quality inspection

    KAUST Repository

    Czajkowski, Jakub

    2011-08-28

    We present the application of ultra-high resolution optical coherence tomography (UHR-OCT) in evaluation of thin, protective films used in printed electronics. Two types of sample were investigated: microscopy glass and organic field effect transistor (OFET) structure. Samples were coated with thin (1-3 μm) layer of parylene C polymer. Measurements were done using experimental UHR-OCT device based on a Kerr-lens mode locked Ti: sapphire femtosecond laser, photonic crystal fibre and modified, free-space Michelson interferometer. Submicron resolution offered by the UHR-OCT system applied in the study enables registration of both interfaces of the thin encapsulation layer. Complete, volumetric characterisation of protective layers is presented, demonstrating possibility to use OCT for encapsulation quality inspection. © Springer-Verlag 2011.

  5. Ultra-High Density Electron Beams for Beam Radiation and Beam Plasma Interaction

    CERN Document Server

    Anderson, Scott; Frigola, Pedro; Gibson, David J; Hartemann, Fred V; Jacob, Jeremy S; Lim, Jae; Musumeci, Pietro; Rosenzweig, James E; Travish, Gil; Tremaine, Aaron M

    2005-01-01

    Current and future applications of high brightness electron beams, which include advanced accelerators such as the plasma wake-field accelerator (PWFA) and beam-radiation interactions such as inverse-Compton scattering (ICS), require both transverse and longitudinal beam sizes on the order of tens of microns. Ultra-high density beams may be produced at moderate energy (50 MeV) by compression and subsequent strong focusing of low emittance, photoinjector sources. We describe the implementation of this method used at LLNL's PLEIADES ICS x-ray source in which the photoinjector-generated beam has been compressed to 300 fsec duration using the velocity bunching technique and focused to 20 μm rms size using an extremely high gradient, permanent magnet quadrupole (PMQ) focusing system.

  6. Herpin effective media resonant underlayers and resonant overlayer designs for ultra-high NA interference lithography.

    Science.gov (United States)

    Bourke, Levi; Blaikie, Richard J

    2017-12-01

    Dielectric waveguide resonant underlayers are employed in ultra-high NA interference photolithography to effectively double the depth of field. Generally a single high refractive index waveguiding layer is employed. Here multilayer Herpin effective medium methods are explored to develop equivalent multilayer waveguiding layers. Herpin equivalent resonant underlayers are shown to be suitable replacements provided at least one layer within the Herpin trilayer supports propagating fields. In addition, a method of increasing the intensity incident upon the photoresist using resonant overlayers is also developed. This method is shown to greatly enhance the intensity within the photoresist making the use of thicker, safer, non-absorbing, low refractive index matching liquids potentially suitable for large-scale applications.

  7. The design and structure of the ultra-high vacuum system of HIRFL-CSR

    International Nuclear Information System (INIS)

    Yang Xiaotian; Zhang Junhui; Zhang Xinjun; Meng Jun; Zhan Wenlong

    2001-01-01

    To minimize the beam loss due to charge exchange of very heavy ions with the residual gas molecules, ultra-high vacuum of 6x10 -9 Pa is required for the HIRFL-CSR facility, which is the lowest pressure in a large vacuum system in China up to now. The total length of the system is about 450 meters and the total inner surface is about 263 square meters. More than 500 standard vacuum components are needed and more than 400 different chambers have to be manufactured. A lot of researches have been down to try to find out the experiences to obtain the required pressure. In this article the following contents are described: the layout of the system; the structure of main vacuum chambers; the treatment method to reduce the outgassing rate of the chamber wall surfaces; vacuum equipment; pressure distribution and the progress of the system

  8. Shape Memory Alloy connectors for Ultra High Vacuum applications: a breakthrough for accelerator technologies

    CERN Document Server

    AUTHOR|(CDS)2091326; Garion, Cedric

    Beam-pipe coupling in particle accelerators is nowadays provided by metallic flanges that are tightly connected by several screws or heavy collars. Their installation and dismounting in radioactive areas contribute to the radiation doses received by the technical personnel. Owing to the increased proton-beam intensity and luminosity of the future High-Luminosity LHC (HL-LHC), radioactivity in some specific zones will be significantly higher than in the present LHC; the presence of the technical staff in these areas will be strictly controlled and minimized. Remote interventions are being considered, too. Shape Memory Alloys (SMAs) offer a unique possibility to generate tight connections and fast clamping/unclamping by remotely changing the temperature of the junction unit. In fact, SMAs exhibit unique strain and stress recovery capabilities which are related to reversible phase transition mechanisms, induced thermally or mechanically. In this PhD work, a novel Ultra-High Vacuum (UHV) coupling system based on ...

  9. Magnetic Microcalorimeter (MMC) Gamma Detectors with Ultra-High Energy Resolution

    Energy Technology Data Exchange (ETDEWEB)

    Friedrich, Stephen [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2018-01-19

    The goal of this LCP is to develop ultra-high resolution gamma detectors based on magnetic microcalorimeters (MMCs) for accurate non-destructive analysis (NDA) of nuclear materials. For highest energy resolution, we will introduce erbium-doped silver (Ag:Er) as a novel sensor material, and implement several geometry and design changes to improve the signal-to-noise ratio. The detector sensitivity will be increased by developing arrays of 32 Ag:Er pixels read out by 16 SQUID preamplifiers, and by developing a cryogenic Compton veto to reduce the spectral background. Since best MMC performance requires detector operation at ~10 mK, we will purchase a dilution refrigerator with a base temperature <10 mK and adapt it for MMC operation. The detector performance will be tested with radioactive sources of interest to the safeguards community.

  10. The nano-mechanical signature of Ultra High Performance Concrete by statistical nanoindentation techniques

    International Nuclear Information System (INIS)

    Sorelli, Luca; Constantinides, Georgios; Ulm, Franz-Josef; Toutlemonde, Francois

    2008-01-01

    Advances in engineering the microstructure of cementitious composites have led to the development of fiber reinforced Ultra High Performance Concretes (UHPC). The scope of this paper is twofold, first to characterize the nano-mechanical properties of the phases governing the UHPC microstructure by means of a novel statistical nanoindentation technique; then to upscale those nanoscale properties, by means of continuum micromechanics, to the macroscopic scale of engineering applications. In particular, a combined investigation of nanoindentation, scanning electron microscope (SEM) and X-ray Diffraction (XRD) indicates that the fiber-matrix transition zone is relatively defect free. On this basis, a four-level multiscale model with defect free interfaces allows to accurately determine the composite stiffness from the measured nano-mechanical properties. Besides evidencing the dominant role of high density calcium silicate hydrates and the stiffening effect of residual clinker, the suggested model may become a useful tool for further optimizing cement-based engineered composites

  11. Magnetic anisotropy in iron thin films evaporated under ultra-high vacuum

    International Nuclear Information System (INIS)

    Dinhut, J.F.; Eymery, J.P.; Krishnan, R.

    1992-01-01

    α-iron thin films with thickness ranging between 20 and 1500 nm have been evaporated using an electron gun under ultra-high vacuum conditions (5.10 -7 P). The columnar structure observed in cross-sectional TEM is related to the large surface diffusion. From Moessbauer spectra the spin orientation is deduced and found to be influenced by the column axis. Spins can be obtained perpendicularly to the film plane by rotating the substrte during the deposition. The magnetization of the samples is reduced by about 30% and the reduction attributed to the interstitial space which increases with the incident angle. The substrate rotation also decreases Ku( parallel ) by a factor 2 and increases Ku( perpendicular to ). (orig.)

  12. Chemical modification of high molecular weight polyethylene through gamma radiation for biomaterials applications

    International Nuclear Information System (INIS)

    Raposo, Matheus P.; Rocha, Marisa C.G.

    2015-01-01

    Ultra high molecular weight polyethylene has been used in the medical field due to its high mechanical properties compared to the other polymers. Its main application is in the development of orthopedic implants, which requires high resistance to abrasion. One of the most used methods is the introduction of crosslinks in the polymer through gamma irradiation. In order to prevent oxidation reactions, studies have been developed using tacoferol (vitamin E) as an antioxidant for the material. The ascorbic acid (vitamin C), however, has been appointed as a viable alternative for vitamin E. In this work, a high molecular weight polyethylene grade (HMWPE) and polyethylene samples formulated with vitamin C were submitted to gamma radiation. Thermodynamic-mechanical methods and gel content determinations were used to characterize the samples obtained. The sample containing 1% of vitamin C and irradiated with 50 KGy of gamma radiation presented the highest content of crosslinks. (author)

  13. Efficient Ultra-High Speed Communication with Simultaneous Phase and Amplitude Regenerative Sampling (SPARS)

    Science.gov (United States)

    Carlowitz, Christian; Girg, Thomas; Ghaleb, Hatem; Du, Xuan-Quang

    2017-09-01

    For ultra-high speed communication systems at high center frequencies above 100 GHz, we propose a disruptive change in system architecture to address major issues regarding amplifier chains with a large number of amplifier stages. They cause a high noise figure and high power consumption when operating close to the frequency limits of the underlying semiconductor technologies. Instead of scaling a classic homodyne transceiver system, we employ repeated amplification in single-stage amplifiers through positive feedback as well as synthesizer-free self-mixing demodulation at the receiver to simplify the system architecture notably. Since the amplitude and phase information for the emerging oscillation is defined by the input signal and the oscillator is only turned on for a very short time, it can be left unstabilized and thus come without a PLL. As soon as gain is no longer the most prominent issue, relaxed requirements for all the other major components allow reconsidering their implementation concepts to achieve further improvements compared to classic systems. This paper provides the first comprehensive overview of all major design aspects that need to be addressed upon realizing a SPARS-based transceiver. At system level, we show how to achieve high data rates and a noise performance comparable to classic systems, backed by scaled demonstrator experiments. Regarding the transmitter, design considerations for efficient quadrature modulation are discussed. For the frontend components that replace PA and LNA amplifier chains, implementation techniques for regenerative sampling circuits based on super-regenerative oscillators are presented. Finally, an analog-to-digital converter with outstanding performance and complete interfaces both to the analog baseband as well as to the digital side completes the set of building blocks for efficient ultra-high speed communication.

  14. Ultra-high-resolution CT angiography of the artery of Adamkiewicz. A feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    Yoshioka, Kunihiro; Tanaka, Ryoichi; Takagi, Hidenobu [Iwate Medical University, Division of Cardiovascular Radiology, Department of Radiology, Morioka (Japan); Ueyama, Yuta; Kikuchi, Kei; Chiba, Takuya [Iwate Medical University Hospital, Center for Radiological Science, Morioka (Japan); Arakita, Kazumasa [Center for Medical Research and Development, Toshiba Medical Systems Corporation, Otawara (Japan); Schuijf, Joanne D. [Center for Medical Research and Development Europe, Toshiba Medical Systems Europe, Zoetermeer (Netherlands); Saito, Yasuo [CT Systems Development Department, Toshiba Medical Systems Corporation, Otawara (Japan)

    2018-01-15

    Preoperative identification of the artery of Adamkiewicz can help prevent postoperative spinal cord injury following thoracic and thoracoabdominal aortic repair. Several studies have demonstrated the feasibility of evaluating the artery of Adamkiewicz using multi-detector row computed tomography (CT), but precise visualization remains a challenge. The present study was conducted to evaluate the usefulness of ultra-high-resolution CT for visualizing the artery of Adamkiewicz with a slice thickness of 0.25 versus 0.5 mm in patients with aortic aneurysms. Our institutional review board approved this study. Twenty-four patients with thoracic and thoracoabdominal aneurysms were scanned with beam collimation of 0.25 mm x 128. Images were reconstructed with slice thicknesses of 0.25 and 0.5 mm. The signal-to-noise ratio (SNR) of the aorta and contrast-to-noise ratio (CNR) between the anterior spinal artery and spinal cord were measured. Two independent observers evaluated visualization of the artery of Adamkiewicz and its continuity between the anterior spinal artery and the aorta using a four-point scale. No significant differences in the SNR of the aorta or CNR of the anterior spinal artery were observed between 0.25- and 0.5-mm slices. The average visualization score was significantly higher for 0.25-mm slices (3.58 ± 0.78) than for 0.5-mm slices (3.13 ± 0.99) (p = 0.01). The percentage of patients with nondiagnostic image quality was significantly lower for 0.25-mm slices (8.3%) than for 0.5-mm slices (33.3%) (p = 0.03). In patients with aortic aneurysms, ultra-high-resolution CT with 0.25-mm slices significantly improves visualization of the artery of Adamkiewicz compared to 0.5-mm slices. (orig.)

  15. Social cognition deficits and the 'ultra high risk' for psychosis population: a review of literature.

    Science.gov (United States)

    Thompson, Andrew D; Bartholomeusz, Cali; Yung, Alison R

    2011-08-01

    A number of risk factors for developing a psychotic disorder have been investigated in the 'ultra high risk' (UHR) population, including neurocognitive abilities, social functioning and, more recently, social cognition. We aimed to review the literature on social cognition in the UHR population. Literature was restricted to English articles and identified using Pubmed, Medline, PsychINFO and CINAHLplus, as well as the reference lists of published studies and reviews. Search terms included social cognition, theory of mind, emotion recognition, attributional style, social knowledge, social perception, 'at risk mental state', psychosis prodrome 'clinical high risk' and 'ultra high risk'. Inclusion criteria were an outcome measure of a social cognition task and an UHR population defined by a structured validated instrument. Seven original research articles met the inclusion criteria, one of which was a conference abstract. One of the two studies that assessed theory of mind, two of the four studies that assessed emotion recognition and both the two studies that assessed social perception/knowledge found significant deficits in UHR patients. The single study that assessed attributional bias also reported differences in UHR patients compared with healthy controls. There is limited published literature on social cognitive performance in the UHR population. Despite this, deficits in certain social cognitive abilities do appear to be present, but further research with more reliable cross-cultural measures is needed. The characterization of social cognitive deficits in the UHR populations may aid in the identification of potential markers for development of a subsequent psychotic disorder, as well as targets for early intervention. © 2011 Blackwell Publishing Asia Pty Ltd.

  16. Ultra high vacuum compatible microwave beam launcher for ECRH in SST - 1

    International Nuclear Information System (INIS)

    Shukla, B.K.; Sathyanarayana, K.; Biswas, P.; Pragnesh, D.; Bora, D.

    2005-01-01

    Microwave beam launcher for Electron Cyclotron Resonance Heating (ECRH) system is used to focus the microwave beam at plasma center of SST -1. The beam launcher consists of an ultra high vacuum (UHV) compatible mirror box with two mirrors mounted in it. One mirror is focusing mirror while other one is a plane mirror. The total volume of the launcher is ∼ 60000 cc and the total surface area exposed to UHV is around ∼ 1.0x10 4 cm 2 . The mirrors are cooled with water for high power and long pulse operation. UHV compatible SS hoses provide flexible cooling connection to the mirrors. Flexible cooling connection helps in adjustment and steering of the mirrors. SS hoses are welded at both the ends and this is necessary to avoid any flange connection inside ultra high vacuum. The system has been tested for UHV compatibility. The leak rate is checked with helium leak detector and found better than l x 10 -9 mbar.lt/s. The system has been baked to 150 deg C for ∼14 hours and the ultimate vacuum achieved with turbomolecular pump (TMP) is ∼ 5x10 -9 mbar. The mirror assembly is tested for leak in pressurized condition using a sniffer probe. The mirrors of the launcher along with the welded bellow are pressurized with helium gas up to a water equivalent pressure of ∼3kg/cm 2 . No increase in the background (∼-10 -6 mbar.lt/s) of the sniffer probes has been observed during the test. The plane mirror is connected with two UHV linear motion feedthroughs with suitable hinges and smooth movement is checked in vacuum. (author)

  17. Integration of ultra-high field MRI and histology for connectome based research of brain disorders

    Directory of Open Access Journals (Sweden)

    Shan eYang

    2013-09-01

    Full Text Available Ultra-high field magnetic resonance imaging (MRI became increasingly relevant for in vivo neuroscientific research because of improved spatial resolutions. However, this is still the unchallenged domain of histological studies, which long played an important role in the investigation of neuropsychiatric disorders. While the field of biological psychiatry strongly advanced on macroscopic levels, current developments are rediscovering the richness of immunohistological information when attempting a multi-level systematic approach to brain function and dysfunction. For most studies, histology sections lost information on three-dimensional reconstructions. Translating histological sections to 3D-volumes would thus not only allow for multi-stain and multi-subject alignment in post mortem data, but also provide a crucial step in big data initiatives involving the network analyses currently performed with in vivo MRI. We therefore investigated potential pitfalls during integration of MR and histological information where no additional blockface information is available. We demonstrated that strengths and requirements from both methods seem to be ideally merged at a spatial resolution of 200 μm. However, the success of this approach is heavily dependent on choices of hardware, sequence and reconstruction. We provide a fully automated pipeline that optimizes histological 3D reconstructions, providing a potentially powerful solution not only for primary human post mortem research institutions in neuropsychiatric research, but also to help alleviate the massive workloads in neuroanatomical atlas initiatives. We further demonstrate (for the first time the feasibility and quality of ultra-high spatial resolution (150 µm isotopic imaging of the entire human brain MRI at 7T, offering new opportunities for analyses on MR-derived information.

  18. Local damage to Ultra High Performance Concrete structures caused by an impact of aircraft engine missiles

    International Nuclear Information System (INIS)

    Riedel, Werner; Noeldgen, Markus; Strassburger, Elmar; Thoma, Klaus; Fehling, Ekkehard

    2010-01-01

    Research highlights: → Experimental series on UHPC panels subjected to aircraft engine impact. → Improved ballistic limit of fiber reinforced UHPC in comparison to conventional R/C. → Detailed investigation of failure mechanisms of fiber reinforced UHPC panel. - Abstract: The impact of an aircraft engine missile causes high stresses, deformations and a severe local damage to conventional reinforced concrete. As a consequence the design of R/C protective structural elements results in components with rather large dimensions. Fiber reinforced Ultra High Performance Concrete (UHPC) is a concrete based material which combines ultra high strength, high packing density and an improved ductility with a significantly increased energy dissipation capacity due to the addition of fiber reinforcement. With those attributes the material is potentially suitable for improved protective structural elements with a reduced need for material resources. The presented paper reports on an experimental series of scaled aircraft engine impact tests with reinforced UHPC panels. The investigations are focused on the material behavior and the damage intensity in comparison to conventional concrete. The fundamental work of is taken as reference for the evaluation of the results. The impactor model of a Phantom F4 GE-J79 engine developed and validated by Sugano et al. is used as defined in the original work. In order to achieve best comparability, the experimental configuration and method are adapted for the UHPC experiments. With 'penetration', 'scabbing' and 'perforation' all relevant damage modes defined in are investigated so that a full set of results are provided for a representative UHPC structural configuration.

  19. An Evaluation of Ultra-High Pressure Regulator for Robotic Lunar Landing Spacecraft

    Science.gov (United States)

    Burnside, Christopher; Trinh, Huu; Pedersen, Kevin

    2011-01-01

    The Robotic Lunar Lander Development (RLLD) Project Office at NASA Marshall Space Flight Center (MSFC) has studied several lunar surface science mission concepts. These missions focus on spacecraft carrying multiple science instruments and power systems that will allow extended operations on the lunar surface. Initial trade studies of launch vehicle options for these mission concepts indicate that the spacecraft design will be significantly mass-constrained. To minimize mass and facilitate efficient packaging, the notional propulsion system for these landers has a baseline of an ultra-high pressure (10,000 psig) helium pressurization system that has been used on Defense missiles. The qualified regulator is capable of short duration use; however, the hardware has not been previously tested at NASA spacecraft requirements with longer duration. Hence, technical risks exist in using this missile-based propulsion component for spacecraft applications. A 10,000-psig helium pressure regulator test activity is being carried out as part of risk reduction testing for MSFC RLLD project. The goal of the test activity is to assess the feasibility of commercial off-the-shelf ultra-high pressure regulator by testing with a representative flight mission profile. Slam-start, gas blowdown, water expulsion, lock-up, and leak tests are also performed on the regulator to assess performance under various operating conditions. The preliminary test results indicated that the regulator can regulate helium to a stable outlet pressure of 740 psig within the +/- 5% tolerance band and maintain a lock-up pressure less than +5% for all tests conducted. Numerous leak tests demonstrated leakage less than 10-3 standard cubic centimeters per second (SCCS) for internal seat leakage at lock-up and less than10-5 SCCS for external leakage through the regulator ambient reference cavity. The successful tests have shown the potential for 10,000 psig helium systems in NASA spacecraft and have reduced risk

  20. Improving distillation method and device of tritiated water analysis for ultra high decontamination efficiency

    International Nuclear Information System (INIS)

    Fang, Hsin-Fa; Wang, Chu-Fang; Lin, Chien-Kung

    2015-01-01

    It is important that monitoring environmental tritiated water for understanding the contamination dispersion of the nuclear facilities. Tritium is a pure beta radionuclide which is usually measured by Liquid Scintillation Counting (LSC). The average energy of tritum beta is only 5.658 keV that makes the LSC counting of tritium easily be interfered by the beta emitted by other radionuclides. Environmental tritiated water samples usually need to be decontaminated by distillation for reducing the interference. After Fukushima Nucleaer Accident, the highest gross beta concentration of groundwater samples obtained around Fukushima Daiichi Nuclear Power Station is over 1,000,000 Bq/l. There is a need for a distillation with ultra-high decontamination efficiency for environmental tritiated water analysis. This study is intended to improve the heating temperature control for better sub-boiling distillation control and modify the height of the container of the air cooling distillation device for better fractional distillation effect. The DF of Cs-137 of the distillation may reach 450,000 which is far better than the prior study. The average loss rate of the improved method and device is about 2.6% which is better than the bias value listed in the ASTM D4107-08. It is proven that the modified air cooling distillation device can provide an easy-handling, water-saving, low cost and effective way of purifying water samples for higher beta radionuclides contaminated water samples which need ultra-high decontamination treatment. - Highlights: • The improvements of method and device make the decontaminatin factor (DF) of Cs-137 of distillation reach over 450,000. • The decontamination factor ( DF) value may be increased about 20 times by increasing the height of the container from 7 cm to 20 cm. • The device provides an easy-handling, water-saving, low cost, stable and effective way for the distillation of triated water analysis.

  1. Ultra high risk of psychosis on committal to a young offender prison: an unrecognised opportunity for early intervention.

    LENUS (Irish Health Repository)

    Flynn, Darran

    2012-08-01

    The ultra high risk state for psychosis has not been studied in young offender populations. Prison populations have higher rates of psychiatric morbidity and substance use disorders. Due to the age profile of young offenders one would expect to find a high prevalence of individuals with pre-psychotic or ultra-high risk mental states for psychosis (UHR). Accordingly young offender institutions offer an opportunity for early interventions which could result in improved long term mental health, social and legal outcomes. In the course of establishing a mental health in-reach service into Ireland\\'s only young offender prison, we sought to estimate unmet mental health needs.

  2. Molecular Understanding of Growth Inhibitory Effect from Irradiated to Bystander Tumor Cells in Mouse Fibrosarcoma Tumor Model

    Science.gov (United States)

    Desai, Sejal; Srambikkal, Nishad; Yadav, Hansa D.; Shetake, Neena; Balla, Murali M. S.; Kumar, Amit; Ray, Pritha; Ghosh, Anu

    2016-01-01

    Even though bystander effects pertaining to radiation risk assessment has been extensively studied, the molecular players of radiation induced bystander effect (RIBE) in the context of cancer radiotherapy are poorly known. In this regard, the present study is aimed to investigate the effect of irradiated tumor cells on the bystander counterparts in mouse fibrosarcoma (WEHI 164 cells) tumor model. Mice co-implanted with WEHI 164 cells γ-irradiated with a lethal dose of 15 Gy and unirradiated (bystander) WEHI 164 cells showed inhibited tumor growth, which was measured in terms of tumor volume and Luc+WEHI 164 cells based bioluminescence in vivo imaging. Histopathological analysis and other assays revealed decreased mitotic index, increased apoptosis and senescence in these tumor tissues. In addition, poor angiogenesis was observed in these tumor tissues, which was further confirmed by fluorescence imaging of tumor vascularisation and CD31 expression by immuno-histochemistry. Interestingly, the growth inhibitory bystander effect was exerted more prominently by soluble factors obtained from the irradiated tumor cells than the cellular fraction. Cytokine profiling of the supernatants obtained from the irradiated tumor cells showed increased levels of VEGF, Rantes, PDGF, GMCSF and IL-2 and decreased levels of IL-6 and SCF. Comparative proteomic analysis of the supernatants from the irradiated tumor cells showed differential expression of total 24 protein spots (21 up- and 3 down-regulated) when compared with the supernatant from the unirradiated control cells. The proteins which showed substantially higher level in the supernatant from the irradiated cells included diphosphate kinase B, heat shock cognate, annexin A1, angiopoietin-2, actin (cytoplasmic 1/2) and stress induced phosphoprotein 1. However, the levels of proteins like annexin A2, protein S100 A4 and cofilin was found to be lower in this supernatant. In conclusion, our results provided deeper insight about

  3. Molecular Understanding of Growth Inhibitory Effect from Irradiated to Bystander Tumor Cells in Mouse Fibrosarcoma Tumor Model.

    Directory of Open Access Journals (Sweden)

    Sejal Desai

    Full Text Available Even though bystander effects pertaining to radiation risk assessment has been extensively studied, the molecular players of radiation induced bystander effect (RIBE in the context of cancer radiotherapy are poorly known. In this regard, the present study is aimed to investigate the effect of irradiated tumor cells on the bystander counterparts in mouse fibrosarcoma (WEHI 164 cells tumor model. Mice co-implanted with WEHI 164 cells γ-irradiated with a lethal dose of 15 Gy and unirradiated (bystander WEHI 164 cells showed inhibited tumor growth, which was measured in terms of tumor volume and Luc+WEHI 164 cells based bioluminescence in vivo imaging. Histopathological analysis and other assays revealed decreased mitotic index, increased apoptosis and senescence in these tumor tissues. In addition, poor angiogenesis was observed in these tumor tissues, which was further confirmed by fluorescence imaging of tumor vascularisation and CD31 expression by immuno-histochemistry. Interestingly, the growth inhibitory bystander effect was exerted more prominently by soluble factors obtained from the irradiated tumor cells than the cellular fraction. Cytokine profiling of the supernatants obtained from the irradiated tumor cells showed increased levels of VEGF, Rantes, PDGF, GMCSF and IL-2 and decreased levels of IL-6 and SCF. Comparative proteomic analysis of the supernatants from the irradiated tumor cells showed differential expression of total 24 protein spots (21 up- and 3 down-regulated when compared with the supernatant from the unirradiated control cells. The proteins which showed substantially higher level in the supernatant from the irradiated cells included diphosphate kinase B, heat shock cognate, annexin A1, angiopoietin-2, actin (cytoplasmic 1/2 and stress induced phosphoprotein 1. However, the levels of proteins like annexin A2, protein S100 A4 and cofilin was found to be lower in this supernatant. In conclusion, our results provided deeper

  4. Development and validation of ultra-high performance supercritical fluid chromatography method for determination of illegal dyes and comparison to ultra-high performance liquid chromatography method.

    Science.gov (United States)

    Khalikova, Maria A; Šatínský, Dalibor; Solich, Petr; Nováková, Lucie

    2015-05-18

    A novel simple, fast and efficient ultra-high performance supercritical fluid chromatography (UHPSFC) method was developed and validated for the separation and quantitative determination of eleven illegal dyes in chili-containing spices. The method involved a simple ultrasound-assisted liquid extraction of illegal compounds with tetrahydrofuran. The separation was performed using a supercritical fluid chromatography system and CSH Fluoro-Phenyl stationary phase at 70°C. The mobile phase was carbon dioxide and the mixture of methanol:acetonitrile (1:1, v/v) with 2.5% formic acid as an additive at the flow rate 2.0 mL min(-1). The UV-vis detection was accomplished at 500 nm for seven compounds and at 420 nm for Sudan Orange G, Butter Yellow, Fast Garnet GBC and Methyl Red due to their maximum of absorbance. All eleven compounds were separated in less than 5 min. The method was successfully validated and applied using three commercial samples of chili-containing spices - Chili sauce (Indonesia), Feferony sauce (Slovakia) and Mojo sauce (Spain). The linearity range of proposed method was 0.50-9.09 mg kg(-1) (r ≥ 0.995). The detection limits were determined as signal to noise ratio of 3 and were ranged from 0.15 mg kg(-1) to 0.60 mg kg(-1) (1.80 mg kg(-1) for Fast Garnet) for standard solution and from 0.25 mg kg(-1) to 1.00 mg kg(-1) (2.50 mg kg(-1) for Fast Garnet, 1.50 mg kg(-1) for Sudan Red 7B) for chili-containing samples. The recovery values were in the range of 73.5-107.2% and relative standard deviation ranging from 0.1% to 8.2% for within-day precision and from 0.5% to 8.8% for between-day precision. The method showed potential for being used to monitor forbidden dyes in food constituents. The developed UHPSFC method was compared to the UHPLC-UV method. The orthogonality of Sudan dyes separation by these two methods was demonstrated. Benefits and drawbacks were discussed showing the reliability of both methods for monitoring of studied illegal dyes in real

  5. Genetic dissection of maize plant architecture with an ultra-high density bin map based on recombinant inbred lines.

    Science.gov (United States)

    Zhou, Zhiqiang; Zhang, Chaoshu; Zhou, Yu; Hao, Zhuanfang; Wang, Zhenhua; Zeng, Xing; Di, Hong; Li, Mingshun; Zhang, Degui; Yong, Hongjun; Zhang, Shihuang; Weng, Jianfeng; Li, Xinhai

    2016-03-03

    Plant architecture attributes, such as plant height, ear height, and internode number, have played an important role in the historical increases in grain yield, lodging resistance, and biomass in maize (Zea mays L.). Analyzing the genetic basis of variation in plant architecture using high density QTL mapping will be of benefit for the breeding of maize for many traits. However, the low density of molecular markers in existing genetic maps has limited the efficiency and accuracy of QTL mapping. Genotyping by sequencing (GBS) is an improved strategy for addressing a complex genome via next-generation sequencing technology. GBS has been a powerful tool for SNP discovery and high-density genetic map construction. The creation of ultra-high density genetic maps using large populations of advanced recombinant inbred lines (RILs) is an efficient way to identify QTL for complex agronomic traits. A set of 314 RILs derived from inbreds Ye478 and Qi319 were generated and subjected to GBS. A total of 137,699,000 reads with an average of 357,376 reads per individual RIL were generated, which is equivalent to approximately 0.07-fold coverage of the maize B73 RefGen_V3 genome for each individual RIL. A high-density genetic map was constructed using 4183 bin markers (100-Kb intervals with no recombination events). The total genetic distance covered by the linkage map was 1545.65 cM and the average distance between adjacent markers was 0.37 cM with a physical distance of about 0.51 Mb. Our results demonstrated a relatively high degree of collinearity between the genetic map and the B73 reference genome. The quality and accuracy of the bin map for QTL detection was verified by the mapping of a known gene, pericarp color 1 (P1), which controls the color of the cob, with a high LOD value of 80.78 on chromosome 1. Using this high-density bin map, 35 QTL affecting plant architecture, including 14 for plant height, 14 for ear height, and seven for internode number were detected

  6. Selective Adsorption of Nano-bio materials and nanostructure fabrication on Molecular Resists Modified by proton beam irradiation

    International Nuclear Information System (INIS)

    Lee, H. W.; Kim, H. S.; Kim, S. M.

    2008-04-01

    The purpose of this research is the fabrication of nanostructures on silicon substrate using proton beam and selectively adsorption of bio-nano materials on the patterned substrate. Recently, the miniaturization of the integrated devices with fine functional structures was intensively investigated, based on combination of nanotechnology (NT), biotechnology (BT) and information technology (IT). Because of the inherent limitation in optical lithography, large variety of novel patterning technologies were evolved to construct nano-structures onto a substrate. Atomic force microscope-based nanolithography has readily formed sub-50 nm patterns by the local modification of a substrate using a probe with a curvature of 10 nm. The surface property was regarded as one of the most important factors for AFM-based nanolithography as well as for other novel nanolithographies. The molecular thin films such as a self-assembled monolayer or a polymer resist layer have been used as an alternative to modifying the surface property. Although proton or ion beam irradiation has been used as an efficient tool to modify the physical, chemical and electrical properties of a surface, the nano-patterning on the substrate or the molecular film modified with the beam irradiation has hardly been studied at both home and abroad. The selective adsorption of nano-bio materials such as carbon nanotubes and proteins on the patterns would contribute to developing the integrated devices. The polystyrene nanoparticles (400 nm) were arrayed on al silicon surface using nanosphere lithography and the various nanopatterns were fabricated by proton beam irradiation on the polystyrene nanoparticles arrayed silicon surface. We obtained the two different nanopatterns such as polymer nanoring patterns and silicon oxide patterns on the same silicon substrate. The polymer nanoring patterns formed by the crosslinkage of polystyrene when proton beam was irradiated at the triangular void spaces that are enclosed by

  7. Molecular nature of mutations induced by high-LET irradiation with argon and carbon ions in Arabidopsis thaliana

    International Nuclear Information System (INIS)

    Hirano, Tomonari; Kazama, Yusuke; Ohbu, Sumie; Shirakawa, Yuki; Liu Yang; Kambara, Tadashi; Fukunishi, Nobuhisa; Abe, Tomoko

    2012-01-01

    Linear energy transfer (LET) is an important parameter to be considered in heavy-ion mutagenesis. However, in plants, no quantitative data are available on the molecular nature of the mutations induced with high-LET radiation above 101–124 keV μm −1 . In this study, we irradiated dry seeds of Arabidopsis thaliana with Ar and C ions with an LET of 290 keV μm −1 . We analyzed the DNA alterations caused by the higher-LET radiation. Mutants were identified from the M 2 pools. In total, 14 and 13 mutated genes, including bin2, egy1, gl1, gl2, hy1, hy3–5, ttg1, and var2, were identified in the plants derived from Ar- and C-ions irradiation, respectively. In the mutants from both irradiations, deletion was the most frequent type of mutation; 13 of the 14 mutated genes from the Ar ion-irradiated plants and 11 of the 13 mutated genes from the C ion-irradiated plants harbored deletions. Analysis of junction regions generated by the 2 types of irradiation suggested that alternative non-homologous end-joining was the predominant pathway of repair of break points. Among the deletions, the proportion of large deletions (>100 bp) was about 54% for Ar-ion irradiation and about 64% for C-ion irradiation. Both current results and previously reported data revealed that the proportions of the large deletions induced by 290-keV μm −1 radiations were higher than those of the large deletions induced by lower-LET radiations (6% for 22.5–30.0 keV μm −1 and 27% for 101–124 keV μm −1 ). Therefore, the 290 keV μm −1 heavy-ion beams can effectively induce large deletions and will prove useful as novel mutagens for plant breeding and analysis of gene functions, particularly tandemly arrayed genes.

  8. Molecular nature of mutations induced by high-LET irradiation with argon and carbon ions in Arabidopsis thaliana

    Energy Technology Data Exchange (ETDEWEB)

    Hirano, Tomonari; Kazama, Yusuke [Nishina Center for Accelerator-Based Science, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Innovation Center, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Ohbu, Sumie; Shirakawa, Yuki; Liu Yang; Kambara, Tadashi; Fukunishi, Nobuhisa [Nishina Center for Accelerator-Based Science, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Abe, Tomoko, E-mail: tomoabe@riken.jp [Nishina Center for Accelerator-Based Science, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Innovation Center, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan)

    2012-07-01

    Linear energy transfer (LET) is an important parameter to be considered in heavy-ion mutagenesis. However, in plants, no quantitative data are available on the molecular nature of the mutations induced with high-LET radiation above 101-124 keV {mu}m{sup -1}. In this study, we irradiated dry seeds of Arabidopsis thaliana with Ar and C ions with an LET of 290 keV {mu}m{sup -1}. We analyzed the DNA alterations caused by the higher-LET radiation. Mutants were identified from the M{sub 2} pools. In total, 14 and 13 mutated genes, including bin2, egy1, gl1, gl2, hy1, hy3-5, ttg1, and var2, were identified in the plants derived from Ar- and C-ions irradiation, respectively. In the mutants from both irradiations, deletion was the most frequent type of mutation; 13 of the 14 mutated genes from the Ar ion-irradiated plants and 11 of the 13 mutated genes from the C ion-irradiated plants harbored deletions. Analysis of junction regions generated by the 2 types of irradiation suggested that alternative non-homologous end-joining was the predominant pathway of repair of break points. Among the deletions, the proportion of large deletions (>100 bp) was about 54% for Ar-ion irradiation and about 64% for C-ion irradiation. Both current results and previously reported data revealed that the proportions of the large deletions induced by 290-keV {mu}m{sup -1} radiations were higher than those of the large deletions induced by lower-LET radiations (6% for 22.5-30.0 keV {mu}m{sup -1} and 27% for 101-124 keV {mu}m{sup -1}). Therefore, the 290 keV {mu}m{sup -1} heavy-ion beams can effectively induce large deletions and will prove useful as novel mutagens for plant breeding and analysis of gene functions, particularly tandemly arrayed genes.

  9. Modifications by γ irradiation of polyethylene at very high molecular weight. Tribological behaviour for orthopedic applications

    International Nuclear Information System (INIS)

    Chaix, N.

    2001-07-01

    A new mode of sterilization by vacuum gamma irradiation is studied. This new mode improves significantly the polyethylene behaviour during the study in friction-corrosion against a stainless steel-316L sphere. (N.C.)

  10. Metamaterial-based transmit and receive system for whole-body magnetic resonance imaging at ultra-high magnetic fields.

    Science.gov (United States)

    Herrmann, Tim; Liebig, Thorsten; Mallow, Johannes; Bruns, Christian; Stadler, Jörg; Mylius, Judith; Brosch, Michael; Svedja, Jan Taro; Chen, Zhichao; Rennings, Andreas; Scheich, Henning; Plaumann, Markus; Hauser, Marcus J B; Bernarding, Johannes; Erni, Daniel

    2018-01-01

    Magnetic resonance imaging (MRI) at ultra-high fields (UHF), such as 7 T, provides an enhanced signal-to-noise ratio and has led to unprecedented high-resolution anatomic images and brain activation maps. Although a variety of radio frequency (RF) coil architectures have been developed for imaging at UHF conditions, they usually are specialized for small volumes of interests (VoI). So far, whole-body coil resonators are not available for commercial UHF human whole-body MRI systems. The goal of the present study was the development and validation of a transmit and receive system for large VoIs that operates at a 7 T human whole-body MRI system. A Metamaterial Ring Antenna System (MRAS) consisting of several ring antennas was developed, since it allows for the imaging of extended VoIs. Furthermore, the MRAS not only requires lower intensities of the irradiated RF energy, but also provides a more confined and focused injection of excitation energy on selected body parts. The MRAS consisted of several antennas with 50 cm inner diameter, 10 cm width and 0.5 cm depth. The position of the rings was freely adjustable. Conformal resonant right-/left-handed metamaterial was used for each ring antenna with two quadrature feeding ports for RF power. The system was successfully implemented and demonstrated with both a silicone oil and a water-NaCl-isopropanol phantom as well as in vivo by acquiring whole-body images of a crab-eating macaque. The potential for future neuroimaging applications was demonstrated by the acquired high-resolution anatomic images of the macaque's head. Phantom and in vivo measurements of crab-eating macaques provided high-resolution images with large VoIs up to 40 cm in xy-direction and 45 cm in z-direction. The results of this work demonstrate the feasibility of the MRAS system for UHF MRI as proof of principle. The MRAS shows a substantial potential for MR imaging of larger volumes at 7 T UHF. This new technique may provide new diagnostic potential

  11. A Monte-Carlo simulation of the equilibrium beam polarization in ultra-high energy electron (positron) storage rings

    International Nuclear Information System (INIS)

    Duan, Zhe; Bai, Mei; Barber, Desmond P.; Qin, Qing

    2015-04-01

    With the recently emerging global interest in building a next generation of circular electron-positron colliders to study the properties of the Higgs boson, and other important topics in particle physics at ultra-high beam energies, it is also important to pursue the possibility of implementing polarized beams at this energy scale. It is therefore necessary to set up simulation tools to evaluate the beam polarization at these ultra-high beam energies. In this paper, a Monte-Carlo simulation of the equilibrium beam polarization based on the Polymorphic Tracking Code(PTC) (Schmidt et al., 2002) is described. The simulations are for a model storage ring with parameters similar to those of proposed circular colliders in this energy range, and they are compared with the suggestion (Derbenev et al., 1978) that there are different regimes for the spin dynamics underlying the polarization of a beam in the presence of synchrotron radiation at ultra-high beam energies. In particular, it has been suggested that the so-called ''correlated'' crossing of spin resonances during synchrotron oscillations at current energies, evolves into ''uncorrelated'' crossing of spin resonances at ultra-high energies.

  12. A Monte-Carlo simulation of the equilibrium beam polarization in ultra-high energy electron (positron) storage rings

    Energy Technology Data Exchange (ETDEWEB)

    Duan, Zhe, E-mail: zhe.duan@ihep.ac.cn [Key Laboratory of Particle Acceleration Physics and Technology, Institute of High Energy Physics, Chinese Academy of Sciences, 100049 Beijing (China); University of Chinese Academy of Sciences, 100049 Beijing (China); Bai, Mei [Forschungszentrum Jülich GmbH, 52428 Jülich (Germany); Barber, Desmond P. [Deutsches Elektronen-Synchrotron, DESY, 22607 Hamburg (Germany); Qin, Qing [Key Laboratory of Particle Acceleration Physics and Technology, Institute of High Energy Physics, Chinese Academy of Sciences, 100049 Beijing (China)

    2015-09-01

    With the recently emerging global interest in building a next generation of circular electron–positron colliders to study the properties of the Higgs boson, and other important topics in particle physics at ultra-high beam energies, it is also important to pursue the possibility of implementing polarized beams at this energy scale. It is therefore necessary to set up simulation tools to evaluate the beam polarization at these ultra-high beam energies. In this paper, a Monte-Carlo simulation of the equilibrium beam polarization based on the Polymorphic Tracking Code (PTC) (Schmidt et al., 2002 [1]) is described. The simulations are for a model storage ring with parameters similar to those of proposed circular colliders in this energy range, and they are compared with the suggestion (Derbenev et al., 1979 [2]) that there are different regimes for the spin dynamics underlying the polarization of a beam in the presence of synchrotron radiation at ultra-high beam energies. In particular, it has been suggested that the so-called “correlated” crossing of spin resonances during synchrotron oscillations at current energies evolves into “uncorrelated” crossing of spin resonances at ultra-high energies.

  13. Opening the Black Box of Cognitive-Behavioural Case Management in Clients with Ultra-High Risk for Psychosis

    DEFF Research Database (Denmark)

    Hartmann, Jessica A.; McGorry, Patrick D.; Schmidt, Stefanie J.

    2017-01-01

    Background: Cognitive-behavioural therapy (CBT) is the first-choice treatment in clients with ultra-high risk (UHR) for psychosis. However, CBT is an umbrella term for a plethora of different strategies, and little is known about the association between the intensity and content of CBT and the se...

  14. Development of Ultra-High Performance Fibre Reinforced Concrete (UHPFRC) : towards an efficient utilization of binders and fibres

    NARCIS (Netherlands)

    Yu, R.; Spiesz, P.R.; Brouwers, H.J.H.

    2015-01-01

    This paper presents a method to develop Ultra-High Performance Fibre Reinforced Concrete (UHPFRC). Towards an efficient utilization of binders and fibres in UHPFRC, the modified Andreasen & Andersen particle packing model and the hybridization design of fibres are utilized. Particularly, the UHPFRC

  15. Development of an eco-friendly Ultra-High Performance Concrete (UHPC) with efficient cement and mineral admixtures uses

    NARCIS (Netherlands)

    Yu, R.; Spiesz, P.R.; Brouwers, H.J.H.

    2015-01-01

    This paper addresses the development of an eco-friendly Ultra-High Performance Concrete (UHPC) with efficient cement and mineral admixtures uses are investigated. The modified Andreasen & Andersen particle packing model is utilized to achieve a densely compacted cementitious matrix. Fly ash (FA),

  16. Retraction Note to: Ultra-High Strength and Ductile Lamellar-Structured Powder Metallurgy Binary Ti-Ta Alloys

    Science.gov (United States)

    Liu, Yong; Xu, Shenghang; Wang, Xin; Li, Kaiyang; Liu, Bin; Wu, Hong; Tang, Huiping

    2018-05-01

    The editors and authors have retracted the article, "Ultra-High Strength and Ductile Lamellar-Structured Powder Metallurgy Binary Ti-Ta Alloys" by Yong Liu, Shenghang Xu, Xin Wang, Kaiyang Li, Bin Liu, Hong Wu, and Huiping Tang (https://doi.org/10.1007/s11837-015-1801-1).

  17. ASBESTOS EXPOSURES DURING ROUTINE FLOOR TILE MAINTENANCE. PART 2: ULTRA HIGH SPEED BURNISHING AND WET-STRIPPING

    Science.gov (United States)

    This study was conducted to evaluate airborne asbestos concentrations during ultra high speed (UHS) burnishing and wet-stripping of asbestos-containing resilient floor tile under two levels of floor care condition (poor and good). Airborne asbestos concentrations were measured by...

  18. Optical Method for Detecting Displacements and Strains at Ultra-High Temperatures During Thermo-Mechanical Testing

    Science.gov (United States)

    Smith, Russell W. (Inventor); Rivers, H. Kevin (Inventor); Sikora, Joseph G. (Inventor); Roth, Mark C. (Inventor); Johnston, William M. (Inventor)

    2016-01-01

    An ultra-high temperature optical method incorporates speckle optics for sensing displacement and strain measurements well above conventional measurement techniques. High temperature pattern materials are used which can endure experimental high temperature environments while simultaneously having a minimum optical aberration. A purge medium is used to reduce or eliminate optical distortions and to reduce, and/or eliminate oxidation of the target specimen.

  19. Pulse shaping for all-optical signal processing of ultra-high bit rate serial data signals

    DEFF Research Database (Denmark)

    Palushani, Evarist

    The following thesis concerns pulse shaping and optical waveform manipulation for all-optical signal processing of ultra-high bit rate serial data signals, including generation of optical pulses in the femtosecond regime, serial-to-parallel conversion and terabaud coherent optical time division...

  20. Trauma and recent life events in individuals at ultra high risk for psychosis: Review and meta-analysis

    NARCIS (Netherlands)

    Kraan, T.; Velthorst, E.; Smit, H.F.E.; de Haan, L.; van der Gaag, M.

    2015-01-01

    Background: Childhood trauma and recent life-events have been related to psychotic disorders. The aim of the present study was to examine whether childhood trauma and recent life-events are significantly more prevalent in patients at Ultra High Risk (UHR) of developing a psychotic disorder compared

  1. Electron attachment to oxygen, ozone and other compounds of atmospheric relevance as studied with ultra-high energy resolution

    International Nuclear Information System (INIS)

    Maerk, T.D.; Matejcik, S.; Kiendler, A.; Cicman, P.; Senn, G.; Skalny, J.; Stampfli, P.; Illenberger, E.; Chu, Y.; Stamatovic, A.

    1996-01-01

    The processes of electron attachment to oxygen, ozone, ozone/oxygen cluster and oxygen cluster as well as other compounds of atmospheric relevance (CF 2 Cl 2 , CHCl 3 and CCl 3 Br) were studied with ultra-high energy resolution crossed beam technique

  2. Depression and social anxiety in help-seeking patients with an ultra-high risk for developing psychosis

    NARCIS (Netherlands)

    Rietdijk, J.; Ising, H.K.; Dragt, S.; Klaassen, R.; Nieman, D.; Wunderink, L.; Cuijpers, P.; Linszen, D.; van der Gaag, M.

    2013-01-01

    Knowledge on associations between ultra-high risk (UHR) for developing psychosis and on non-psychotic psychopathology in help-seeking populations is limited with respect to differences between male and female patients. The present study tests the hypothesis that both social anxiety and depression

  3. Environmental factors and social adjustment as predictors of a first psychosis in subjects at ultra high risk

    NARCIS (Netherlands)

    Dragt, Sara; Nieman, Dorien H.; Veltman, Doede; Becker, Hiske E.; van de Fliert, Reinaud; de Haan, Lieuwe; Linszen, Don H.

    2011-01-01

    BACKGROUND: The onset of schizophrenia is associated with genetic, symptomatic, social and environmental risk factors. The aim of the present study was to determine which environmental factors may contribute to a prediction of a first psychotic episode in subjects at Ultra High Risk (UHR) for

  4. Opening the Black Box of Cognitive-Behavioural Case Management in Clients with Ultra-High Risk for Psychosis

    NARCIS (Netherlands)

    Hartmann, Jessica A.; McGorry, Patrick D.; Schmidt, Stefanie J.; Amminger, G. Paul; Yuen, Hok Pan; Markulev, Connie; Berger, Gregor E.; Chen, Eric Y. H.; de Haan, Lieuwe; Hickie, Ian B.; Lavoie, Suzie; McHugh, Meredith J.; Mossaheb, Nilufar; Nieman, Dorien H.; Nordentoft, Merete; Riecher-Rössler, Anita; Schäfer, Miriam R.; Schlögelhofer, Monika; Smesny, Stefan; Thompson, Andrew; Verma, Swapna Kamal; Yung, Alison R.; Nelson, Barnaby

    2017-01-01

    Background: Cognitive-behavioural therapy (CBT) is the first-choice treatment in clients with ultra-high risk (UHR) for psychosis. However, CBT is an umbrella term for a plethora of different strategies, and little is known about the association between the intensity and content of CBT and the

  5. Static properties and impact resistance of a green Ultra-High Performance Hybrid Fibre Reinforced Concrete (UHPHFRC) : experiments and modeling

    NARCIS (Netherlands)

    Yu, R.; Spiesz, P.R.; Brouwers, H.J.H.

    2014-01-01

    This paper addresses the static properties and impact resistance of a "green" Ultra-High Performance Hybrid Fibre Reinforced Concrete (UHPHFRC). The design of concrete mixtures aims to achieve a densely compacted cementitious matrix, employing the modified Andreasen & Andersen particle packing

  6. Increased Saccadic Rate during Smooth Pursuit Eye Movements in Patients at Ultra High Risk for Developing a Psychosis

    Science.gov (United States)

    van Tricht, M. J.; Nieman, D. H.; Bour, L. J.; Boeree, T.; Koelman, J. H. T. M.; de Haan, L.; Linszen, D. H.

    2010-01-01

    Abnormalities in eye tracking are consistently observed in schizophrenia patients and their relatives and have been proposed as an endophenotype of the disease. The aim of this study was to investigate the performance of patients at Ultra High Risk (UHR) for developing psychosis on a task of smooth pursuit eye movement (SPEM). Forty-six UHR…

  7. Gains in QTL detection using an ultra-high density SNP map based on population sequencing relative to traditional RFLP/SSR markers.

    Directory of Open Access Journals (Sweden)

    Huihui Yu

    Full Text Available Huge efforts have been invested in the last two decades to dissect the genetic bases of complex traits including yields of many crop plants, through quantitative trait locus (QTL analyses. However, almost all the studies were based on linkage maps constructed using low-throughput molecular markers, e.g. restriction fragment length polymorphisms (RFLPs and simple sequence repeats (SSRs, thus are mostly of low density and not able to provide precise and complete information about the numbers and locations of the genes or QTLs controlling the traits. In this study, we constructed an ultra-high density genetic map based on high quality single nucleotide polymorphisms (SNPs from low-coverage sequences of a recombinant inbred line (RIL population of rice, generated using new sequencing technology. The quality of the map was assessed by validating the positions of several cloned genes including GS3 and GW5/qSW5, two major QTLs for grain length and grain width respectively, and OsC1, a qualitative trait locus for pigmentation. In all the cases the loci could be precisely resolved to the bins where the genes are located, indicating high quality and accuracy of the map. The SNP map was used to perform QTL analysis for yield and three yield-component traits, number of tillers per plant, number of grains per panicle and grain weight, using data from field trials conducted over years, in comparison to QTL mapping based on RFLPs/SSRs. The SNP map detected more QTLs especially for grain weight, with precise map locations, demonstrating advantages in detecting power and resolution relative to the RFLP/SSR map. Thus this study provided an example for ultra-high density map construction using sequencing technology. Moreover, the results obtained are helpful for understanding the genetic bases of the yield traits and for fine mapping and cloning of QTLs.

  8. Irradiation with X-rays phase-advances the molecular clockwork in liver, adrenal gland and pancreas.

    Science.gov (United States)

    Müller, Mareike Hildegard; Rödel, Franz; Rüb, Udo; Korf, Horst-Werner

    2015-02-01

    The circadian clock of man and mammals shows a hierarchic organization. The master clock, located in the suprachiasmatic nuclei (SCN), controls peripheral oscillators distributed throughout the body. Rhythm generation depends on molecular clockworks based on transcriptional/translational interaction of clock genes. Numerous studies have shown that the clockwork in peripheral oscillators is capable to maintain circadian rhythms for several cycles in vitro, i.e. in the absence of signals from the SCN. The aim of the present study is to analyze the effects of irradiation with X-rays on the clockwork of liver, adrenal and pancreas. To this end organotypic slice cultures of liver (OLSC) and organotypic explant cultures of adrenal glands (OAEC) and pancreas (OPEC) were prepared from transgenic mPer2(luc) mice which express luciferase under the control of the promoter of an important clock gene, Per2, and allow to study the dynamics of the molecular clockwork by bioluminometry. The preparations were cultured in a membrane-based liquid-air interface culturing system and irradiated with X-rays at doses of 10 Gy and 50 Gy or left untreated. Bioluminometric real-time recordings show a stable oscillation of all OLSC, OAEC and OPEC for up to 12 days in vitro. Oscillations persist after irradiation with X-rays. However, a dose of 50 Gy caused a phase advance in the rhythm of the OLSC by 5 h, in the OPEC by 7 h and in the OAEC by 6 h. Our study shows that X-rays affect the molecular clockwork in liver, pancreas and adrenal leading to phase advances. Our results confirm and extend previous studies showing a phase-advancing effect of X-rays at the level of the whole animal and single cells.

  9. Ultra-high field upper extremity peripheral nerve and non-contrast enhanced vascular imaging.

    Directory of Open Access Journals (Sweden)

    Shailesh B Raval

    Full Text Available The purpose of this study was to explore the efficacy of Ultra-high field [UHF] 7 Tesla [T] MRI as compared to 3T MRI in non-contrast enhanced [nCE] imaging of structural anatomy in the elbow, forearm, and hand [upper extremity].A wide range of sequences including T1 weighted [T1] volumetric interpolate breath-hold exam [VIBE], T2 weighted [T2] double-echo steady state [DESS], susceptibility weighted imaging [SWI], time-of-flight [TOF], diffusion tensor imaging [DTI], and diffusion spectrum imaging [DSI] were optimized and incorporated with a radiofrequency [RF] coil system composed of a transverse electromagnetic [TEM] transmit coil combined with an 8-channel receive-only array for 7T upper extremity [UE] imaging. In addition, Siemens optimized protocol/sequences were used on a 3T scanner and the resulting images from T1 VIBE and T2 DESS were compared to that obtained at 7T qualitatively and quantitatively [SWI was only qualitatively compared]. DSI studio was utilized to identify nerves based on analysis of diffusion weighted derived fractional anisotropy images. Images of forearm vasculature were extracted using a paint grow manual segmentation method based on MIPAV [Medical Image Processing, Analysis, and Visualization].High resolution and high quality signal-to-noise ratio [SNR] and contrast-to-noise ratio [CNR]-images of the hand, forearm, and elbow were acquired with nearly homogeneous 7T excitation. Measured [performed on the T1 VIBE and T2 DESS sequences] SNR and CNR values were almost doubled at 7T vs. 3T. Cartilage, synovial fluid and tendon structures could be seen with higher clarity in the 7T T1 and T2 weighted images. SWI allowed high resolution and better quality imaging of large and medium sized arteries and veins, capillary networks and arteriovenous anastomoses at 7T when compared to 3T. 7T diffusion weighted sequence [not performed at 3T] demonstrates that the forearm nerves are clearly delineated by fiber tractography. The

  10. Quantitative analysis of localized stresses in irradiated stainless steels using high resolution electron backscatter diffraction and molecular dynamics modeling

    International Nuclear Information System (INIS)

    Johnson, D.C.; Kuhr, B.; Farkas, D.; Was, G.S.

    2016-01-01

    Quantitative measurements of stress near dislocation channel–grain boundary (DC–GB) interaction sites were made using high resolution electron backscatter diffraction (HREBSD) and have been compared with molecular dynamics (MD) simulations. Tensile stress normal to the grain boundary was significantly elevated at discontinuous DC–GB intersections with peak magnitudes roughly an order of magnitude greater than at sites where slip transfer occurred. These results constitute the first measurement of stress amplification at DC–GB intersections and provide support to the theory that high normal stress at the grain boundary may be a key driver for the initiation of irradiation assisted stress corrosion cracks.

  11. Chemical modification of high molecular weight polyethylene through gamma radiation for biomaterials applications; Modificacao quimica de polietileno de alto peso molecular atraves de radiacao gama para aplicacao em biomateriais

    Energy Technology Data Exchange (ETDEWEB)

    Raposo, Matheus P.; Rocha, Marisa C.G., E-mail: matheusmerlim@hotmail.com [Universidade Estado do Rio de Janeiro (UERJ), Nova Friburgo, RJ (Brazil). Instituto Politecnico

    2015-07-01

    Ultra high molecular weight polyethylene has been used in the medical field due to its high mechanical properties compared to the other polymers. Its main application is in the development of orthopedic implants, which requires high resistance to abrasion. One of the most used methods is the introduction of crosslinks in the polymer through gamma irradiation. In order to prevent oxidation reactions, studies have been developed using tacoferol (vitamin E) as an antioxidant for the material. The ascorbic acid (vitamin C), however, has been appointed as a viable alternative for vitamin E. In this work, a high molecular weight polyethylene grade (HMWPE) and polyethylene samples formulated with vitamin C were submitted to gamma radiation. Thermodynamic-mechanical methods and gel content determinations were used to characterize the samples obtained. The sample containing 1% of vitamin C and irradiated with 50 KGy of gamma radiation presented the highest content of crosslinks. (author)

  12. Ultra-high vacuum system of the Brookhaven National Synchrotron Light Source

    Energy Technology Data Exchange (ETDEWEB)

    Foerster, C.L.

    1995-12-31

    The rings of the National Synchrotron Light Source (NSLS) have been supplying light to numerous users for approximately a decade and we recently enjoyed a fully conditioned machine vacuum at design currents. A brief description of the X-Ray storage ring, the VUV storage ring and their current supply is given along with some of their features. The ultra-high vacuum system employed for the storage rings and their advantages for the necessary stored beam environments are discussed including, a brief history of time. After several hundred amp hours of stored beam current operation, very little improvement in machine performance was seen due to conditioning. Sections of the rings were vented, to dry nitrogen and replacement components were pre-baked and pre-argon glow conditioned prior to installation. Very little machine conditioning was needed to return to operation after recovering vacuum due to well established conditioning procedures. All straight sections in the X-Ray ring and the VUV ring have been filled with various insertion devices and most are fully operational. Each storage ring has a computer controlled total pressure and partial pressure monitoring system for the ring and its beam ports, to insure good vacuum.

  13. Photoionization study of doubly-excited helium at ultra-high resolution

    Energy Technology Data Exchange (ETDEWEB)

    Kaindl, G.; Schulz, K.; Domke, M. [Freie Universitaet Berlin (Germany)] [and others

    1997-04-01

    Ever since the pioneering work of Madden & Codling and Cooper, Fano & Prats on doubly-excited helium in the early sixties, this system may be considered as prototypical for the study of electron-electron correlations. More detailed insight into these states could be reached only much later, when improved theoretical calculations of the optically-excited {sup 1}P{sup 0} double-excitation states became available and sufficiently high energy resolution ({delta}E=4.0 meV) was achieved. This allowed a systematic investigation of the double-excitation resonances of He up to excitation energies close to the double-ionization threshold, I{sub infinity}=79.003 eV, which stimulated renewed theoretical interest into these correlated electron states. The authors report here on striking progress in energy resolution in this grazing-incidence photon-energy range of grating monochromators and its application to hitherto unobservable states of doubly-excited He. By monitoring an extremely narrow double-excitation resonance of He, with a theoretical lifetime width of less than or equal to 5 {mu}eV, a resolution of {delta}E=1.0 meV (FWHM) at 64.1 eV could be achieved. This ultra-high spectral resolution, combined with high photon flux, allowed the investigation of new Rydberg resonances below the N=3 ionization threshold, I{sub 3}, as well as a detailed comparison with ab-initio calculations.

  14. Reflecting and Polarizing Properties of Conductive Fabrics in Ultra-High Frequency Range

    Directory of Open Access Journals (Sweden)

    Oleg Kiprijanovič

    2015-09-01

    Full Text Available The system based on ultra-wide band (UWB signals was employed for qualitative estimation of attenuating, reflecting and polarizing properties of conductive fabrics, capable to prevent local static charge accumulation. Pulsed excitation of triangle monopole antenna of 6.5 cm height by rectangular electric pulses induced radiation of UWB signals with spectral density of power having maximum in ultra-high frequency (UHF range. The same antenna was used for the radiated signal receiving. Filters and amplifiers of different passband were employed to divide UHF range into subranges of 0.3-0.55 GHz, 0.55-1 GHz, 1-2 GHz and 2-4 GHz bands. The free space method, when conductive fabric samples of 50x50 cm2 were placed between transmitting and receiving antennas, was used to imitate a practical application. Received wideband signals corresponding to the defined range were detected by unbiased detectors. The fabrics made of two types of warps, containing different threads with conductive yarns, were investigated. It was estimated attenuation and reflective properties of the fabrics when electric field is collinear or perpendicular to thread direction. In the UHF range it was revealed good reflecting properties of the fabrics containing metallic component in the threads. The system has advantages but not without a certain shortcoming. Adapting it for specific tasks should lead to more effective usage, including yet unused properties of the UWB signals.

  15. Search for Ultra High-Energy Neutrinos with AMANDA-II

    International Nuclear Information System (INIS)

    IceCube Collaboration; Klein, Spencer; Ackermann, M.

    2007-01-01

    A search for diffuse neutrinos with energies in excess of 10 5 GeV is conducted with AMANDA-II data recorded between 2000 and 2002. Above 10 7 GeV, the Earth is essentially opaque to neutrinos. This fact, combined with the limited overburden of the AMANDA-II detector (roughly 1.5 km), concentrates these ultra high-energy neutrinos at the horizon. The primary background for this analysis is bundles of downgoing, high-energy muons from the interaction of cosmic rays in the atmosphere. No statistically significant excess above the expected background is seen in the data, and an upper limit is set on the diffuse all-flavor neutrino flux of E 2 Φ 90%CL -7 GeV cm -2 s -1 sr -1 valid over the energy range of 2 x 10 5 GeV to 10 9 GeV. A number of models which predict neutrino fluxes from active galactic nuclei are excluded at the 90% confidence level

  16. Development of fast heating electron beam annealing setup for ultra high vacuum chamber

    International Nuclear Information System (INIS)

    Das, Sadhan Chandra; Majumdar, Abhijit; Hippler, R.; Katiyal, Sumant; Shripathi, T.

    2014-01-01

    We report the design and development of a simple, electrically low powered and fast heating versatile electron beam annealing setup (up to 1000 °C) working with ultra high vacuum (UHV) chamber for annealing thin films and multilayer structures. The important features of the system are constant temperature control in UHV conditions for the temperature range from room temperature to 1000 ºC with sufficient power of 330 W, at constant vacuum during annealing treatment. It takes approximately 6 min to reach 1000 °C from room temperature (∼10 −6 mbar) and 45 min to cool down without any extra cooling. The annealing setup consists of a UHV chamber, sample holder, heating arrangement mounted on suitable UHV electrical feed-through and electronic control and feedback systems to control the temperature within ±1 ºC of set value. The outside of the vacuum chamber is cooled by cold air of 20 °C of air conditioning machine used for the laboratory, so that chamber temperature does not go beyond 50 °C when target temperature is maximum. The probability of surface oxidation or surface contamination during annealing is examined by means of x-ray photoelectron spectroscopy of virgin Cu sample annealed at 1000 °C

  17. A strategy to unveil transient sources of ultra-high-energy cosmic rays

    Directory of Open Access Journals (Sweden)

    Takami Hajime

    2013-06-01

    Full Text Available Transient generation of ultra-high-energy cosmic rays (UHECRs has been motivated from promising candidates of UHECR sources such as gamma-ray bursts, flares of active galactic nuclei, and newly born neutron stars and magnetars. Here we propose a strategy to unveil transient sources of UHECRs from UHECR experiments. We demonstrate that the rate of UHECR bursts and/or flares is related to the apparent number density of UHECR sources, which is the number density estimated on the assumption of steady sources, and the time-profile spread of the bursts produced by cosmic magnetic fields. The apparent number density strongly depends on UHECR energies under a given rate of the bursts, which becomes observational evidence of transient sources. It is saturated at the number density of host galaxies of UHECR sources. We also derive constraints on the UHECR burst rate and/or energy budget of UHECRs per source as a function of the apparent source number density by using models of cosmic magnetic fields. In order to obtain a precise constraint of the UHECR burst rate, high event statistics above ∼ 1020 eV for evaluating the apparent source number density at the highest energies and better knowledge on cosmic magnetic fields by future observations and/or simulations to better estimate the time-profile spread of UHECR bursts are required. The estimated rate allows us to constrain transient UHECR sources by being compared with the occurrence rates of known energetic transient phenomena.

  18. Influence of the atmosphere on the space detection of ultra-high energy cosmic rays

    International Nuclear Information System (INIS)

    Moreggia, S.

    2007-06-01

    EUSO (Extreme Universe Space Observatory) is a project of ultra-high energy (> 10 20 eV) cosmic rays detection from space. Its concept relies on the observation of fluorescence and Cerenkov photons emitted by extensive air showers from a telescope located on the International Space Station. A simulation software has been developed to study the characteristics of this innovative concept of detection. It deals with the different steps of the detection chain: extensive air shower development, emission of fluorescence and Cerenkov light, and radiative transfer to the telescope. A Monte-Carlo code has been implemented to simulate the propagation of photons through the atmosphere, dealing with multiple scattering in clear sky conditions as well as in presence of aerosols and clouds. With this simulation program, the impact of atmospheric conditions on the performance of a space-located detector has been studied. The precise treatment of photons propagation through the atmosphere has permitted to quantify the scattered light contribution to the detected signal. (author)

  19. Search for ultra-high energy photons with AMIGA muon counters

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, Nicolas Martin [Instituto de Tecnologias en Deteccion y Astroparticulas, Buenos Aires (Argentina); Institut fuer Kernphysik, Karlsruher Institut fuer Technologie. (Germany); Collaboration: Pierre-Auger-Collaboration

    2016-07-01

    The study of the composition of ultra-high energy (UHE) cosmic rays (CR) is one of the topical problems of astroparticle physics. The discovery of UHE photons, i.e. photons with energies around 1 EeV, in primary cosmic rays could be of particular interest for the field of astroparticle physics, and also for fundamental physics, since they are tracers of the highest-energy processes in the Universe. For the search for UHE photons at the Pierre Auger Observatory (PAO), several parameters have been proposed to distinguish between primary hadrons and photons. One of the most promising approaches to search for primary gamma rays is the study of the muon component in extensive air showers (EAS) produced in the interaction between the CR and the nuclei in the atmosphere. The number of muons in showers induced by gamma primaries is an order of magnitude lower than the hadronic primaries counterpart. The AMIGA extension of the PAO, consisting of an array of buried scintillators counters, allows the study of the muons produced during the EAS development. In this talk, the sensitivity of the muon counters to photon-initiated EAS and the possible discrimination procedures are discussed using dedicated EAS simulations with software package CORSIKA, including the detector response using the Offline package developed by the Pierre Auger Collaboration.

  20. Dynamic ultra high speed Scheimpflug imaging for assessing corneal biomechanical properties

    Directory of Open Access Journals (Sweden)

    Renato Ambrósio Jr

    2013-04-01

    Full Text Available OBJECTIVE: To describe a novel technique for clinical characterization of corneal biomechanics using non-invasive dynamic imaging. METHODS: Corneal deformation response during non contact tonometry (NCT is monitored by ultra-high-speed (UHS photography. The Oculus Corvis ST (Scheimpflug Technology; Wetzlar, Germany has a UHS Scheimpflug camera, taking over 4,300 frames per second and of a single 8mm horizontal slit, for monitoring corneal deformation response to NCT. The metered collimated air pulse or puff has a symmetrical configuration and fixed maximal internal pump pressure of 25 kPa. The bidirectional movement of the cornea in response to the air puff is monitored. RESULTS: Measurement time is 30ms, with 140 frames acquired. Advanced algorithms for edge detection of the front and back corneal contours are applied for every frame. IOP is calculated based on the first applanation moment. Deformation amplitude (DA is determined as the highest displacement of the apex in the highest concavity (HC moment. Applanation length (AL and corneal velocity (CVel are recorded during ingoing and outgoing phases. CONCLUSION: Corneal deformation can be monitored during non contact tonometry. The parameters generated provide clinical in vivo characterization of corneal biomechanical properties in two dimensions, which is relevant for different applications in Ophthalmology.

  1. Effect of ultra high pressure homogenization treatment on the bioactive compounds of soya milk.

    Science.gov (United States)

    Toro-Funes, N; Bosch-Fusté, J; Veciana-Nogués, M T; Vidal-Carou, M C

    2014-01-01

    Ultra high pressure homogenization (UHPH) is a useful novel technology to obtain safe and high-quality liquid foods. The effect of UHPH at 200 and 300 MPa in combination with different inlet temperatures (Tin) (55, 65 and 75 °C) on the bioactive compounds of soya milk was studied. Total phytosterols increased with the higher combination of pressure and temperature. The main phytosterol was β-sitosterol, followed by stigmasterol and campesterol. Total tocopherols in UHPH-treated soya milks decreased as the temperature and pressure increased. UHPH treatment also affected the different chemical forms of tocopherols. No biogenic amines were detected in any of the analyzed soya milks. Meanwhile, the polyamines SPD and SPM were found in all soya milks, being stable to the UHPH treatment. Total isoflavones increased with the higher combination of pressure and temperature. No differences in the isoflavone profile were found, with β-glucoside conjugates being the predominant form. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. Ground Glass Pozzolan in Conventional, High, and Ultra-High Performance Concrete

    Directory of Open Access Journals (Sweden)

    Tagnit-Hamou Arezki

    2018-01-01

    Full Text Available Ground-glass pozzolan (G obtained by grinding the mixed-waste glass to same fineness of cement can act as a supplementary-cementitious material (SCM, given that it is an amorphous and a pozzolanic material. The G showed promising performances in different concrete types such as conventional concrete (CC, high-performance concrete (HPC, and ultra-high performance concrete (UHPC. The current paper reports on the characteristics and performance of G in these concrete types. The use of G provides several advantages (technological, economical, and environmental. It reduces the production cost of concrete and decrease the carbon footprint of a traditional concrete structures. The rheology of fresh concrete can be improved due to the replacement of cement by non-absorptive glass particles. Strength and rigidity improvements in the concrete containing G are due to the fact that glass particles act as inclusions having a very high strength and elastic modulus that have a strengthening effect on the overall hardened matrix.

  3. Native oxidation of ultra high purity Cu bulk and thin films

    International Nuclear Information System (INIS)

    Iijima, J.; Lim, J.-W.; Hong, S.-H.; Suzuki, S.; Mimura, K.; Isshiki, M.

    2006-01-01

    The effect of microstructure and purity on the native oxidation of Cu was studied by using angle-resolved X-ray photoelectron spectroscopy (AR-XPS) and spectroscopic ellipsometry (SE). A high quality copper film prepared by ion beam deposition under a substrate bias voltage of -50 V (IBD Cu film at V s = -50 V) showed an oxidation resistance as high as an ultra high purity copper (UHP Cu) bulk, whereas a Cu film deposited without substrate bias voltage (IBD Cu film at V s = 0 V) showed lower oxidation resistance. The growth of Cu 2 O layer on the UHP Cu bulk and both types of the films obeyed in principle a logarithmic rate law. However, the growth of oxide layer on the IBD Cu films at V s = 0 and -50 V deviated upward from the logarithmic rate law after the exposure time of 320 and 800 h, respectively. The deviation from the logarithmic law is due to the formation of CuO on the Cu 2 O layer after a critical time

  4. An Intelligent Sensor for the Ultra-High-Frequency Partial Discharge Online Monitoring of Power Transformers

    Directory of Open Access Journals (Sweden)

    Jian Li

    2016-05-01

    Full Text Available Ultra-high-frequency (UHF partial discharge (PD online monitoring is an effective way to inspect potential faults and insulation defects in power transformers. The construction of UHF PD online monitoring system is a challenge because of the high-frequency and wide-frequency band of the UHF PD signal. This paper presents a novel, intelligent sensor for UHF PD online monitoring based on a new method, namely a level scanning method. The intelligent sensor can directly acquire the statistical characteristic quantities and is characterized by low cost, few data to output and transmit, Ethernet functionality, and small size for easy installation. The prototype of an intelligent sensor was made. Actual UHF PD experiments with three typical artificial defect models of power transformers were carried out in a laboratory, and the waveform recording method and intelligent sensor proposed were simultaneously used for UHF PD measurement for comparison. The results show that the proposed intelligent sensor is qualified for the UHF PD online monitoring of power transformers. Additionally, three methods to improve the performance of intelligent sensors were proposed according to the principle of the level scanning method.

  5. Advanced intermediate temperature sodium-nickel chloride batteries with ultra-high energy density

    Science.gov (United States)

    Li, Guosheng; Lu, Xiaochuan; Kim, Jin Y.; Meinhardt, Kerry D.; Chang, Hee Jung; Canfield, Nathan L.; Sprenkle, Vincent L.

    2016-02-01

    Sodium-metal halide batteries have been considered as one of the more attractive technologies for stationary electrical energy storage, however, they are not used for broader applications despite their relatively well-known redox system. One of the roadblocks hindering market penetration is the high-operating temperature. Here we demonstrate that planar sodium-nickel chloride batteries can be operated at an intermediate temperature of 190 °C with ultra-high energy density. A specific energy density of 350 Wh kg-1, higher than that of conventional tubular sodium-nickel chloride batteries (280 °C), is obtained for planar sodium-nickel chloride batteries operated at 190 °C over a long-term cell test (1,000 cycles), and it attributed to the slower particle growth of the cathode materials at the lower operating temperature. Results reported here demonstrate that planar sodium-nickel chloride batteries operated at an intermediate temperature could greatly benefit this traditional energy storage technology by improving battery energy density, cycle life and reducing material costs.

  6. Advanced MR methods at ultra-high field (7 Tesla) for clinical musculoskeletal applications

    Energy Technology Data Exchange (ETDEWEB)

    Trattnig, Siegfried [Medical University of Vienna/Vienna General Hospital, MR Centre - High Field MR, Department of Radiology, Vienna (Austria); Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Austrian Cluster for Tissue Regeneration, Vienna (Austria); Zbyn, Stefan; Schmitt, Benjamin; Friedrich, Klaus; Bogner, Wolfgang [Medical University of Vienna/Vienna General Hospital, MR Centre - High Field MR, Department of Radiology, Vienna (Austria); Juras, Vladimir; Szomolanyi, Pavol [Medical University of Vienna/Vienna General Hospital, MR Centre - High Field MR, Department of Radiology, Vienna (Austria); Slovak Academy of Sciences, Department of Imaging Methods, Institute of Measurement Science, Bratislava (Slovakia)

    2012-11-15

    This article provides an overview of the initial clinical results of musculoskeletal studies performed at 7 Tesla, with special focus on sodium imaging, new techniques such as chemical exchange saturation transfer (CEST) and T2* imaging, and multinuclear MR spectroscopy. Sodium imaging was clinically used at 7 T in the evaluation of patients after cartilage repair procedures because it enables the GAG content to be monitored over time. Sodium imaging and T2* mapping allow insights into the ultra-structural composition of the Achilles tendon and help detect early disease. Chemical exchange saturation transfer was, for the first time, successfully applied in the clinical set-up at 7 T in patients after cartilage repair surgery. The potential of phosphorus MR spectroscopy in muscle was demonstrated in a comparison study between 3 and 7 T, with higher spectral resolution and significantly shorter data acquisition times at 7 T. These initial clinical studies demonstrate the potential of ultra-high field MR at 7 T, with the advantage of significantly improved sensitivity for other nuclei, such as {sup 23}Na (sodium) and {sup 31}P (phosphorus). The application of non-proton imaging and spectroscopy provides new insights into normal and abnormal physiology of musculoskeletal tissues, particularly cartilage, tendons, and muscles. (orig.)

  7. Harding - a field case study: Sand control strategy for ultra-high productivity and injectivity wells

    Energy Technology Data Exchange (ETDEWEB)

    McKay, G.; Bennett, C.; Price-Smith, C.; Dowell, S.; McLellan, W. [British Petroleum (United Kingdom)

    1998-12-31

    The strategy adopted and the factors considered in the development of the sandface completion design for Phase One of the Harding Field in the unconsolidated Balder Massive Sand in the U.K. Sector of the North Sea is described. The field development utilizes a TPG 500 Jack-up Drilling and Production Unit in conjunction with a concrete gravity base tank (GBT). The first phase of the development involved drilling and completing horizontal wells sand-free, ultra-high production (over 30,000 BOPD/well, with PI in excess of 1,000 bbl/day/psi). The experiences showed that pre-packed screens can be successfully utilized to provide lasting sand control with high rate of production in clean homogenous sandstones, and that testing for fluid compatibility, formation damage, screen plugging, corrosion and erosion potential are essential pre-requisites in determining the optimal solution in any well with sand production potential.The experiences gained in Phase One have contributed to design enhancements for Phase Two of the project which include extended reach horizontal wells to neighbouring satellite pools. 3 refs., 1 tab., 8 figs.

  8. An Ultra-High-Density, Transcript-Based, Genetic Map of Lettuce

    Science.gov (United States)

    Truco, Maria José; Ashrafi, Hamid; Kozik, Alexander; van Leeuwen, Hans; Bowers, John; Wo, Sebastian Reyes Chin; Stoffel, Kevin; Xu, Huaqin; Hill, Theresa; Van Deynze, Allen; Michelmore, Richard W.

    2013-01-01

    We have generated an ultra-high-density genetic map for lettuce, an economically important member of the Compositae, consisting of 12,842 unigenes (13,943 markers) mapped in 3696 genetic bins distributed over nine chromosomal linkage groups. Genomic DNA was hybridized to a custom Affymetrix oligonucleotide array containing 6.4 million features representing 35,628 unigenes of Lactuca spp. Segregation of single-position polymorphisms was analyzed using 213 F7:8 recombinant inbred lines that had been generated by crossing cultivated Lactuca sativa cv. Salinas and L. serriola acc. US96UC23, the wild progenitor species of L. sativa. The high level of replication of each allele in the recombinant inbred lines was exploited to identify single-position polymorphisms that were assigned to parental haplotypes. Marker information has been made available using GBrowse to facilitate access to the map. This map has been anchored to the previously published integrated map of lettuce providing candidate genes for multiple phenotypes. The high density of markers achieved in this ultradense map allowed syntenic studies between lettuce and Vitis vinifera as well as other plant species. PMID:23550116

  9. An Ultra-High-Density, Transcript-Based, Genetic Map of Lettuce.

    Science.gov (United States)

    Truco, Maria José; Ashrafi, Hamid; Kozik, Alexander; van Leeuwen, Hans; Bowers, John; Wo, Sebastian Reyes Chin; Stoffel, Kevin; Xu, Huaqin; Hill, Theresa; Van Deynze, Allen; Michelmore, Richard W

    2013-04-09

    We have generated an ultra-high-density genetic map for lettuce, an economically important member of the Compositae, consisting of 12,842 unigenes (13,943 markers) mapped in 3696 genetic bins distributed over nine chromosomal linkage groups. Genomic DNA was hybridized to a custom Affymetrix oligonucleotide array containing 6.4 million features representing 35,628 unigenes of Lactuca spp. Segregation of single-position polymorphisms was analyzed using 213 F 7:8 recombinant inbred lines that had been generated by crossing cultivated Lactuca sativa cv. Salinas and L. serriola acc. US96UC23, the wild progenitor species of L. sativa The high level of replication of each allele in the recombinant inbred lines was exploited to identify single-position polymorphisms that were assigned to parental haplotypes. Marker information has been made available using GBrowse to facilitate access to the map. This map has been anchored to the previously published integrated map of lettuce providing candidate genes for multiple phenotypes. The high density of markers achieved in this ultradense map allowed syntenic studies between lettuce and Vitis vinifera as well as other plant species. Copyright © 2013 Truco et al.

  10. [Determination of lutein in infant formula milk powder using ultra-high performance liquid chromatography].

    Science.gov (United States)

    Wang, Lin; Huang, Junrong; Zhang, Li; Feng, Feng; Ling, Yun; Chu, Xiaogang; Li, Hongliang

    2013-12-01

    An ultra-high performance liquid chromatography (U-HPLC) method for the determination of lutein in the infant formula milk powder was developed. The sample was extracted with acetone and defatted using freezing centrifugation method. The U-HPLC separation was achieved using a YMC Carotenoid C30 column (150 mm x 4.6 mm, 3 microm) with the mixture of methanol/methyl tert-butyl ether (70: 30, v/v) as the mobile phase under isocratic elution. The flow rate was 0.5 mL/min and the column oven temperature was 25 degrees C. The injection volume was 5 microL. It was detected on a photodiode array detector at a wavelength of 445 nm. The results showed that the linear range was 20-500 microg/L (r = 0.9999), and the limit of quantification was 20 microg/L. The mean recoveries of lutein varied from 97.9% to 104.4% spiked at 50, 250 and 2,000 microg/kg. The established method is simple, accurate and sensitive for the rapid determination of lutein in infant formula milk powder.

  11. Vacuum Bloch-Siegert shift in Landau polaritons with ultra-high cooperativity

    Science.gov (United States)

    Li, Xinwei; Bamba, Motoaki; Zhang, Qi; Fallahi, Saeed; Gardner, Geoff C.; Gao, Weilu; Lou, Minhan; Yoshioka, Katsumasa; Manfra, Michael J.; Kono, Junichiro

    2018-06-01

    A two-level system resonantly interacting with an a.c. magnetic or electric field constitutes the physical basis of diverse phenomena and technologies. However, Schrödinger's equation for this seemingly simple system can be solved exactly only under the rotating-wave approximation, which neglects the counter-rotating field component. When the a.c. field is sufficiently strong, this approximation fails, leading to a resonance-frequency shift known as the Bloch-Siegert shift. Here, we report the vacuum Bloch-Siegert shift, which is induced by the ultra-strong coupling of matter with the counter-rotating component of the vacuum fluctuation field in a cavity. Specifically, an ultra-high-mobility two-dimensional electron gas inside a high-Q terahertz cavity in a quantizing magnetic field revealed ultra-narrow Landau polaritons, which exhibited a vacuum Bloch-Siegert shift up to 40 GHz. This shift, clearly distinguishable from the photon-field self-interaction effect, represents a unique manifestation of a strong-field phenomenon without a strong field.

  12. An ultra-high-vacuum multiple grating chamber and scan drive with improved grating change

    International Nuclear Information System (INIS)

    Hulbert, S.L.; Holly, D.J.; Middleton, F.H.; Wallace, D.J.; Wisconsin Univ., Stoughton, WI; Wisconsin Univ., Stoughton, WI

    1989-01-01

    We describe a new grating chamber and scan drive which has been designed, built, and tested by Physical Sciences Laboratory of the University of Wisconsin for the new high flux, high-resolution spectroscopy branch line of the TOK hybrid wiggler/undulator on the NSLS VUV ring. The chamber will contain spherical gratings to be used in the Spherical Grating Monochromator (SGM) configuration introduced by Chen and Sette. The grating chamber houses five 180 mm x 35 mm x 30 mm gratings capable of scanning a range of 12 degree (-14 degree to +8 degree with respect to the incoming beam direction) for VUV and soft X-ray diffraction. The gratings can be switched and precisely indexed while under ultra-high vacuum (UHV) at any scan angle and are mechanically isolated from the vacuum chamber to prevent inaccuracies due to chamber distortions. The gratings can separately be adjusted for height, yaw, pitch, and roll, with the latter three performed while in vacuo. The scan drive provides a resolution of 0.03 arc sec with linearity over the 12 degree range of ∼1.5 arc sec and absolute reproducibility of 1 arc sec. 5 refs., 5 figs

  13. Ultra-High Pressure Homogenization enhances physicochemical properties of soy protein isolate-stabilized emulsions.

    Science.gov (United States)

    Fernández-Ávila, C; Escriu, R; Trujillo, A J

    2015-09-01

    The effect of Ultra-High Pressure Homogenization (UHPH, 100-300MPa) on the physicochemical properties of oil-in-water emulsions prepared with 4.0% (w/v) of soy protein isolate (SPI) and soybean oil (10 and 20%, v/v) was studied and compared to emulsions treated by conventional homogenization (CH, 15MPa). CH emulsions were prepared with non-heated and heated (95°C for 15min) SPI dispersions. Emulsions were characterized by particle size determination with laser diffraction, rheological properties using a rotational rheometer by applying measurements of flow curve and by transmission electron microscopy. The variation on particle size and creaming was assessed by Turbiscan® analysis, and visual observation of the emulsions was also carried out. UHPH emulsions showed much smaller d 3.2 values and greater physical stability than CH emulsions. The thermal treatment of SPI prior CH process did not improve physical stability properties. In addition, emulsions containing 20% of oil exhibited greater physical stability compared to emulsions containing 10% of oil. Particularly, UHPH emulsions treated at 100 and 200MPa with 20% of oil were the most stable due to low particle size values (d 3.2 and Span), greater viscosity and partial protein denaturation. These results address the physical stability improvement of protein isolate-stabilized emulsions by using the emerging UHPH technology. Copyright © 2015 Elsevier Ltd. All rights reserved.

  14. Effects of Ultra-High Pressure Homogenization and Hydrocolloids on Physicochemical and Storage Properties of Soymilk.

    Science.gov (United States)

    Mukherjee, Dipaloke; Chang, Sam K C; Zhang, Yin; Mukherjee, Soma

    2017-10-01

    This study investigated the efficacy of ultra-high pressure homogenization (UHPH) in the presence or absence of added hydrocolloids for enhancing a range of physic-chemical properties of soymilk-which are important for extending shelf-life. Soymilk preparations containing different concentrations (0.01%, 0.02%, and 0.05%, w/v) of 2 different hydrocolloids (κ-carrageenan, κ-C, and gum Arabic, GA) were subjected to 3 different levels of UHPH (70, 140, and 210 MPa) and stored in sterilized containers at 4 °C. Emulsion properties of the soymilk preparations were analyzed over a period of 5 weeks. The results showed that soymilk with 0.05% κ-C had markedly improved storage properties, evident by significantly (P homogenization and addition of hydrocolloids to prevent aggregation of soymilk particles and the retention of antioxidant capacity. The results showed enhancement of the quality of soymilk during storage. The techniques developed can be adopted by the food industry. © 2017 Institute of Food Technologists®.

  15. Experimental and analytical study on biodiesel and diesel spray characteristics under ultra-high injection pressure

    International Nuclear Information System (INIS)

    Wang Xiangang; Huang Zuohua; Kuti, Olawole Abiola; Zhang Wu; Nishida, Keiya

    2010-01-01

    Spray characteristics of biodiesels (from palm and cooked oil) and diesel under ultra-high injection pressures up to 300 MPa were studied experimentally and analytically. Injection delay, spray penetration, spray angle, spray projected area and spray volume were measured in a spray vessel using a high speed video camera. Air entrainment and atomization characteristics were analyzed with the quasi-steady jet theory and an atomization model respectively. The study shows that biodiesels give longer injection delay and spray tip penetration. Spray angle, projected area and volume of biodiesels are smaller than those of diesel fuel. The approximately linear relationship of non-dimensional spray tip penetration versus time suggests that the behavior of biodiesel and diesel sprays is similar to that of gaseous turbulent jets. Calculation from the quasi-steady jet theory shows that the air entrainment of palm oil is worse than that of diesel, while the cooked oil and diesel present comparable air entrainment characteristics. The estimation on spray droplet size shows that biodiesels generate larger Sauter mean diameter due to higher viscosity and surface tension.

  16. Recent Results on Ultra-High Energy Cosmic Rays from the Telescope Array

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    TA's recent results on Ultra-High Energy Cosmic Rays (UHECRs) are reported. The energy spectrum based on 20k events above 10^18.2 eV demonstrates a clear dip at 10^18.7 eV and a cutoff at 10^19.7 eV , the shape and the energies of which are well described by the GZK process: energy loss of extra-galactic protons by the interaction with the CMB and IR background. The primary composition obtained from the shower maximum analysis using the hybrid technique is consistent with 100% proton or light nuclei, and inconsistent with 100% iron up to 10^19.3 eV. Above the GZK cutoff energy, a large flux enhancement of medium size (radius=20deg) is observed in the direction of Ursa-Major. The chance probability of this hotspot appearing from the isotropic flux is 4.0sigma. The center of the hotspot is 19 deg off from the Super-Galactic Plane, and no obvious candidate of UHECRs is known in this direction.

  17. EFFECT OF ULTRA-HIGH PRESSURE HOMOGENIZATION ON THE INTERACTION BETWEEN BOVINE CASEIN MICELLES AND RITONAVIR

    Science.gov (United States)

    Corzo-Martínez, M.; Mohan, M.; Dunlap, J.; Harte, F.

    2014-01-01

    Purpose The aim of this work was to develop a milk-based powder formulation appropriate for pediatric delivery of ritonavir (RIT). Methods Ultra-high pressure homogenization (UHPH) at 0.1, 300 and 500 MPa was used to process a dispersion of pasteurized skim milk (SM) and ritonavir. Loading efficiency was determined by RP-HPLC-UV; characterization of RIT:SM systems was carried out by apparent average hydrodynamic diameter and rheological measurements as well as different analytical techniques including Trp fluorescence, UV spectroscopy, DSC, FTIR and SEM; and delivery capacity of casein micelles was determined by in vitro experiments promoting ritonavir release. Results Ritonavir interacted efficiently with milk proteins, especially, casein micelles, regardless of the processing pressure; however, results suggest that, at 0.1 MPa, ritonavir interacts with caseins at the micellar surface, whilst, at 300 and 500 MPa, ritonavir is integrated to the protein matrix during UHPH treatment. Likewise, in vitro experiments showed that ritonavir release from micellar casein systems is pH dependent; with a high retention of ritonavir during simulated gastric digestion and a rapid delivery under conditions simulating the small intestine environment. Conclusions Skim milk powder, especially, casein micelles are potentially suitable and efficient carrier systems to develop novel milk-based and low-ethanol powder formulations of ritonavir appropriate for pediatric applications. PMID:25270571

  18. A Simple Semaphore Signaling Technique for Ultra-High Frequency Spacecraft Communications

    Science.gov (United States)

    Butman, S.; Satorius, E.; Illott, P.

    2005-11-01

    For planetary lander missions such as the upcoming Phoenix mission to Mars, the most challenging phase of the spacecraft-to-ground communications is during the critical phase termed entry, descent, and landing (EDL). At 8.4 GHz (X-band), the signals received by the largest Deep Space Network (DSN) antennas can be too weak for even 1 bit per second (bps) and therefore not able to communicate critical information to Earth. Fortunately, the lander's ultra-high frequency (UHF) link to an orbiting relay can meet the EDL requirements, but the data rate needs to be low enough to fit the capability of the UHF link during some or all of EDL. On Phoenix, the minimum data rate of the as-built UHF radio is 8 kbps and requires a signal level at the Odyssey orbiter of at least minus 120 dBm. For lower signaling levels, the effective data rate needs to be reduced, but without incurring the cost of rebuilding and requalifying the equipment. To address this scenario, a simple form of frequency-shift keying (FSK) has been devised by appropriately programming the data stream that is input to the UHF transceiver. This article describes this technique and provides performance estimates. Laboratory testing reveals that input signal levels at minus 140 dBm and lower can routinely be demodulated with the proposed signaling scheme, thereby providing a 20-dB and greater margin over the 8-kbps threshold.

  19. Niacin Skin Sensitivity Is Increased in Adolescents at Ultra-High Risk for Psychosis.

    Directory of Open Access Journals (Sweden)

    Gregor E Berger

    Full Text Available Most studies provide evidence that the skin flush response to nicotinic acid (niacin stimulation is impaired in schizophrenia. However, only little is known about niacin sensitivity in the ultra-high risk (UHR phase of psychotic disorders.We compared visual ratings of niacin sensitivity between adolescents at UHR for psychosis according to the one year transition outcome (UHR-T n = 11; UHR-NT n = 55 with healthy controls (HC n = 25 and first episode schizophrenia patients (FEP n = 25 treated with atypical antipsychotics.Contrary to our hypothesis niacin sensitivity of the entire UHR group was not attenuated, but significantly increased compared to the HC group, whereas no difference could be found between the UHR-T and UHR-NT groups. As expected, niacin sensitivity of FEP was attenuated compared to HC group. In UHR individuals niacin sensitivity was inversely correlated with omega-6 and -9 fatty acids (FA, but positively correlated with phospholipase A2 (inPLA2 activity, a marker of membrane lipid repair/remodelling.Increased niacin sensitivity in UHR states likely indicates an impaired balance of eicosanoids and omega-6/-9 FA at a membrane level. Our findings suggest that the emergence of psychosis is associated with an increased mobilisation of eicosanoids prior to the transition to psychosis possibly reflecting a "pro-inflammatory state", whereas thereafter eicosanoid mobilisation seems to be attenuated. Potential treatment implications for the UHR state should be further investigated.

  20. Ultra-High Density Single Nanometer-Scale Anodic Alumina Nanofibers Fabricated by Pyrophosphoric Acid Anodizing

    Science.gov (United States)

    Kikuchi, Tatsuya; Nishinaga, Osamu; Nakajima, Daiki; Kawashima, Jun; Natsui, Shungo; Sakaguchi, Norihito; Suzuki, Ryosuke O.

    2014-12-01

    Anodic oxide fabricated by anodizing has been widely used for nanostructural engineering, but the nanomorphology is limited to only two oxides: anodic barrier and porous oxides. Therefore, the discovery of an additional anodic oxide with a unique nanofeature would expand the applicability of anodizing. Here we demonstrate the fabrication of a third-generation anodic oxide, specifically, anodic alumina nanofibers, by anodizing in a new electrolyte, pyrophosphoric acid. Ultra-high density single nanometer-scale anodic alumina nanofibers (1010 nanofibers/cm2) consisting of an amorphous, pure aluminum oxide were successfully fabricated via pyrophosphoric acid anodizing. The nanomorphologies of the anodic nanofibers can be controlled by the electrochemical conditions. Anodic tungsten oxide nanofibers can also be fabricated by pyrophosphoric acid anodizing. The aluminum surface covered by the anodic alumina nanofibers exhibited ultra-fast superhydrophilic behavior, with a contact angle of less than 1°, within 1 second. Such ultra-narrow nanofibers can be used for various nanoapplications including catalysts, wettability control, and electronic devices.