Infrared microspectroscopy of live cells in microfluidic devices (MD-IRMS): toward a powerful label-free cell-based assay.

Science.gov (United States)

Vaccari, L; Birarda, G; Businaro, L; Pacor, S; Grenci, G

2012-06-05

Until nowadays most infrared microspectroscopy (IRMS) experiments on biological specimens (i.e., tissues or cells) have been routinely carried out on fixed or dried samples in order to circumvent water absorption problems. In this paper, we demonstrate the possibility to widen the range of in-vitro IRMS experiments to vibrational analysis of live cellular samples, thanks to the development of novel biocompatible IR-visible transparent microfluidic devices (MD). In order to highlight the biological relevance of IRMS in MD (MD-IRMS), we performed a systematic exploration of the biochemical alterations induced by different fixation protocols, ethanol 70% and formaldehyde solution 4%, as well as air-drying on U937 leukemic monocytes by comparing their IR vibrational features with the live U937 counterpart. Both fixation and air-drying procedures affected lipid composition and order as well as protein structure at a different extent while they both induced structural alterations in nucleic acids. Therefore, only IRMS of live cells can provide reliable information on both DNA and RNA structure and on their cellular dynamic. In summary, we show that MD-IRMS of live cells is feasible, reliable, and biologically relevant to be recognized as a label-free cell-based assay.

LC/IRMS analysis: A powerful technique to trace carbon flow in microphytobenthic communities in intertidal sediments

Science.gov (United States)

Moerdijk-Poortvliet, Tanja C. W.; Stal, Lucas J.; Boschker, Henricus T. S.

2014-09-01

Microphytobenthic communities are important for primary production in intertidal marine sediments. Extracellular polymeric substances (EPS), comprising polysaccharides and proteins, play a key role in the structure and functioning of microphytobenthic biofilms and allow interactions between the benthic microalgae and the associated heterotrophic bacteria. The use of stable isotopes has provided major insights into the functioning of these microbial ecosystems. Until recently, gas chromatography-isotope ratio mass spectrometry (GC/IRMS) was the principal method for compound specific stable isotope analysis in these studies. Liquid chromatography linked to IRMS (LC/IRMS) is a more recently developed technique that broadens the range of compounds that can be targeted, in particular enabling the analysis of 13C in non-volatile, aqueous soluble organic compounds, such as carbohydrates and amino acids. In this paper we present an overview of the possibilities and limitations of the LC/IRMS technique to study metabolic processes in microphytobenthic biofilms consisting of mainly diatoms. With a preliminary in-situ labeling experiment, we show that the biosynthesis of carbohydrates and amino acids in EPS and total carbohydrate and amino acid pools can be determined by LC/IRMS. Water extractable EPS were composed predominantly of carbohydrates, whereas amino acids played a minor role, both in terms of content and production. By using LC/IRMS, we will be able to quantify the biosynthesis of metabolites and, hence, to unravel in detail the metabolic pathways of the transfer of carbon from the diatoms via EPS to the bacteria.

La prise en charge du détenu en IRM

OpenAIRE

Laurent, Alizée; Tunez, Roxane; Jorge, José

2016-01-01

Ce travail traite de la problématique suivante : ’’Comment les TRM prennent-ils en charge les patients détenus lors d’un examen d’IRM?’’. Celle-ci est inspirée de l’aspect de la sécurité liée à la présence d’une personne privée de liberté en tant que patient. Elle concerne aussi l’équipement ferromagnétique, incompatible à l’IRM, présent dans une telle situation sur le détenu ainsi que sur le personnel de sécurité l’accompagnant. De plus, il y a l’aspect des droits du patient et du respect de...

On the use of IRMS in forensic science: proposals for a methodological approach.

Science.gov (United States)

Gentile, Natacha; Besson, Luc; Pazos, Diego; Delémont, Olivier; Esseiva, Pierre

2011-10-10

The flourishing number of publications on the use of isotope ratio mass spectrometry (IRMS) in forensic science denotes the enthusiasm and the attraction generated by this technology. IRMS has demonstrated its potential to distinguish chemically identical compounds coming from different sources. Despite the numerous applications of IRMS to a wide range of forensic materials, its implementation in a forensic framework is less straightforward than it appears. In addition, each laboratory has developed its own strategy of analysis on calibration, sequence design, standards utilisation and data treatment without a clear consensus. Through the experience acquired from research undertaken in different forensic fields, we propose a methodological framework of the whole process using IRMS methods. We emphasize the importance of considering isotopic results as part of a whole approach, when applying this technology to a particular forensic issue. The process is divided into six different steps, which should be considered for a thoughtful and relevant application. The dissection of this process into fundamental steps, further detailed, enables a better understanding of the essential, though not exhaustive, factors that have to be considered in order to obtain results of quality and sufficiently robust to proceed to retrospective analyses or interlaboratory comparisons. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Development of a GC/C/IRMS method--confirmation of a novel steroid profiling approach in doping control.

Science.gov (United States)

Van Renterghem, Pieter; Polet, Michael; Brooker, Lance; Van Gansbeke, Wim; Van Eenoo, Peter

2012-09-01

In doping control, an athlete can only be convicted with the misuse with endogenous steroids like testosterone (T), if abnormal values of steroid metabolites and steroid ratios are observed and if the subsequent analysis with isotope ratios mass spectrometry (IRMS) confirms the presence of exogenously administered androgens. In this work, we compare the results of a novel steroid profiling approach with the performance an in-house developed IRMS method. The developed IRMS has the advantage over other methods to be relatively short in time and with target compounds androsterone, etiocholanolone, 5β-androstane 3α,17β-diol and 5α-androstane 3α,17β-diol. Pregnanediol was used as an endogenous reference compound (ERC). Reference limits for the IRMS values were established and applied as decision limits for the evaluation of excretion urine from administration with oral T, T-gel, dihydrotestosterone (DHT) - gel and dehydroepiandrosterone (DHEA). Results indicated the importance of both androstanediols as important IRMS markers where relative values compared to an ERC (Δδ(13)C) yielded better detection accuracy than absolute δ(13)C-values. The detection times of all administered endogenous steroids were evaluated using the proposed thresholds. The results of traditional steroid profiling and a new approach based upon minor steroid metabolites monitoring introduced in a longitudinal framework were evaluated with IRMS. With traditional steroid profiling methods, 95% of the atypical samples could be confirmed whereas an additional 74% of IRMS confirmed was provided by a new biomarkers strategy. These results prove that the other steroid profiling strategies can improve the efficiency in detection of misuse with endogenous steroids. Copyright © 2012 Elsevier Inc. All rights reserved.

The function analysis of full-length cDNA sequence from IRM-2 mouse cDNA library

International Nuclear Information System (INIS)

Wang Qin; Liu Xiaoqiu; Xu Chang; Du Liqing; Sun Zhijuan; Wang Yan; Liu Qiang; Song Li; Li Jin; Fan Feiyue

2013-01-01

Objective: To identify the function of full-length cDNA sequence from IRM-2 mouse cDNA library. Methods: Full-length cDNA products were amplified by PCR from IRM-2 mouse cDNA library according to twenty-one pieces of expressed sequence tag. The expression of full-length cDNAs were detected after mouse embryonic fibroblasts were exposed to 6.5 Gy γ-ray radiation. And the effect on the growth of radiosensitivity cells AT5B1VA transfected with full-length cDNAs was investigated. Results: The expression of No.4, 5 and 2 full-length cDNAs from IRM-2 mouse were higher than that of parental ICR and 615 mouse after mouse embryonic fibroblasts irradiated with γ-ray radiation. And the survival rate of AT5B1VA cells transfected with No.4, 5 and 2 full-length cDNAs was high. Conclusion: No.4, 5 and 2 full-length cDNAs of IRM-2 mouse are of high radioresistance. (authors)

Isotope ratio monitoring LC/MS (IRM-LC/MS): new applications

International Nuclear Information System (INIS)

Juchelka, D; Hilkert, A.; Krummen, M.

2005-01-01

With the introduction of compound specific isotope analysis by isotope ratio monitoring GC/ MS (IRM-GC/MS) the immediate demand for similar applications using HPLC was created. Many compounds of biological, medical, pharmaceutical and environmental interest are not volatile or too polar. Consequently, they cannot be directly analyzed by gas chromatography. In IRM-GC/MS the carrier is helium, which does not interfere with the essential combust ion step prior to isotope ratio mass spectrometry (IRMS). In opposite the LC mobile phase has inhibited a similar direct conversion up to now. All earlier IRM-LC/MS approaches were based on the removal of the liquid phase prior to combustion risking fractionation of the isotope ratios of the eluted compounds. To avoid such restrictions we developed a new continuous flow concept for the coupling of an HPLC system to the isotope ratio MS for 13 C/ 12C isotope ratio analysis. In the Finnigan LC IsoLink, the liquid phase is not removed from the sample prior to oxidation. The sample is oxidized still in the mobile phase followed by on-line separation of the CO 2 from the liquid phase and transfer into the isotope ratio MS. Therefore, this strategy is based on water and inorganic buffers as mobile phase. The new approach opens up a whole new world in the application of gas isotope ratio mass spectrometry. The 13 C/ 12 C ratio s of organic acids, amino acids, carbohydrates and nucleotides can now be measured. These components typically within a complex matrix are separated by liquid chromatography followed by on-line determination of the isotope ratios. The draw backs of using derivatization and off-line preparation procedures can now be over come. This new technique allow s studying biochemical cycles, running tracer experiments and determining the origin of components. Applications from different scientific areas such as biogeochemistry, molecular biology, and pharmacy as well as authenticity control o f foods will be presented

Forensic analysis of explosives using isotope ratio mass spectrometry (IRMS)--preliminary study on TATP and PETN.

Science.gov (United States)

Benson, Sarah J; Lennard, Christopher J; Maynard, Philip; Hill, David M; Andrew, Anita S; Roux, Claude

2009-06-01

The application of isotopic techniques to investigations requiring the provision of evidence to a Court is limited. The objective of this research was to investigate the application of light stable isotopes and isotope ratio mass spectrometry (IRMS) to solve complex forensic cases by providing a level of discrimination not achievable utilising traditional forensic techniques. Due to the current threat of organic peroxide explosives, such as triacetone triperoxide (TATP), research was undertaken to determine the potential of IRMS to differentiate samples of TATP that had been manufactured utilising different starting materials and/or manufacturing processes. In addition, due to the prevalence of pentaerythritoltetranitrate (PETN) in detonators, detonating cord, and boosters, the potential of the IRMS technique to differentiate PETN samples from different sources was also investigated. Carbon isotope values were measured in fourteen TATP samples, with three definite groups appearing in the initial sample set based on the carbon data alone. Four additional TATP samples (in a second set of samples) were distinguishable utilising the carbon and hydrogen isotopic compositions individually, and also in combination with the oxygen isotope values. The 3D plot of the carbon, oxygen and hydrogen data demonstrated the clear discrimination of the four samples of TATP. The carbon and nitrogen isotope values measured from fifteen PETN samples, allowed samples from different sources to be readily discriminated. This paper demonstrates the successful application of IRMS to the analysis of explosives of forensic interest to assist in discriminating samples from different sources. This research represents a preliminary evaluation of the IRMS technique for the measurement of stable isotope values in TATP and PETN samples, and supports the dedication of resources for a full evaluation of this application in order to achieve Court reportable IRMS results.

Compound-specific nitrogen and carbon isotope analysis of nitroaromatic compounds in aqueous samples using solid-phase microextraction coupled to GC/IRMS.

Science.gov (United States)

Berg, Michael; Bolotin, Jakov; Hofstetter, Thomas B

2007-03-15

Solid-phase microextraction (SPME) coupled to gas chromatography/isotope ratio mass spectrometry was used to determine the delta15N and delta13C signatures of selected nitroaromatic contaminants such as the explosive 2,4,6-trinitrotoluene (TNT) for derivation of isotopic enrichment factors of contaminant transformation. Parameters for efficient extraction of nitroaromatic compounds (NACs) and substituted anilines from water samples were evaluated by SPME-GC/MS. delta13C signatures determined by SPME-GC/IRMS and elemental analyzer IRMS (EA-IRMS) were in good agreement, generally within +/-0.7 per thousand, except for 2,4-dinitrotoluene (2,4-DNT) and TNT, which showed slight deviations (IRMS were between 73 and 780 microg L-1 and correlated with the extraction efficiencies of the compounds determined by SPME-GC/MS. Nitrogen isotope measurements by SPME-GC/IRMS were of similar precision (standard deviations IRMS within +/-1.3 per thousand (+2.5 per thousand for TNT), but no systematic trend was found for the deviations. LODs of delta15N measurements ranged from 1.6 to 9.6 mg L-1 for nitrotoluenes, chlorinated NACs and DNTs (22 mg L-1 for TNT). The SPME-GC/IRMS method is well suited for the determination of isotopic enrichment factors of various NAC transformation processes and provides so far unexplored possibilities to elucidate behavior and degradation mechanisms of nitroaromatic contaminants in soils and groundwaters.

Comparison of IRMS and NMR spectrometry for the determination of intramolecular 13C isotope composition: application to ethanol.

Science.gov (United States)

Gilbert, Alexis; Hattori, Ryota; Silvestre, Virginie; Wasano, Nariaki; Akoka, Serge; Hirano, Satoshi; Yamada, Keita; Yoshida, Naohiro; Remaud, Gérald S

2012-09-15

Isotopic (13)C NMR is a relatively recent technique which allows the determination of intramolecular (13)C isotope composition at natural abundance. It has been used in various scientific fields such as authentication, counterfeiting or plant metabolism. Although its precision has already been evaluated, the determination of its trueness remains still challenging. To deal with that issue, a comparison with another normalized technique must be achieved. In this work, we compare the intramolecular (13)C isotope distribution of ethanol from different origins obtained using both Isotope Ratio Mass Spectrometry (IRMS) and Nuclear Magnetic Resonance (NMR) spectrometry techniques. The IRMS approach consists of the oxidation of ethanol to acetic acid followed by the degradation of the latter for the analysis of each fragments formed. We show here that the oxidation of ethanol to acetic acid does not bring any significant error on the determination of the site-specific δ(13)C (δ(13)C(i)) of ethanol using the IRMS approach. The difference between the data obtained for 16 samples from different origins using IRMS and NMR approaches is not statistically significant and remains below 0.3‰. These results are encouraging for the future studies using isotopic NMR, especially in combination with the IRMS approach. Copyright © 2012. Published by Elsevier B.V.

Review: Current applications and challenges for liquid chromatography coupled to isotope ratio mass spectrometry (LC/IRMS).

Science.gov (United States)

Godin, Jean-Philippe; McCullagh, James S O

2011-10-30

High-precision isotope analysis is recognized as an essential research tool in many fields of study. Until recently, continuous flow isotope ratio mass spectrometry (CF-IRMS) was available via an elemental analyzer or a gas chromatography inlet system for compound-specific analysis of light stable isotopes. In 2004, however, an interface that coupled liquid chromatography with IRMS (LC/IRMS) became commercially available for the first time. This brought the capability for new areas of application, in particular enabling compound-specific δ(13)C analysis of non-volatile, aqueous soluble, compounds from complex mixtures. The interface design brought with it several analytical constraints, however, in particular a lack of compatibility with certain types of chromatography as well as limited flow rates and mobile phase compositions. Routine LC/IRMS methods have, however, been established for measuring the δ(13)C isotopic ratios of underivatized individual compounds for application in archeology, nutrition and physiology, geochemistry, hydrology, soil science and food authenticity. Seven years after its introduction, we review the technical advances and constraints, methodological developments and new applications of liquid chromatography coupled to isotope ratio mass spectrometry. Copyright © 2011 John Wiley & Sons, Ltd.

200-ZP-1 IRM phase 2 and 3 remedial design report, Revision 1

International Nuclear Information System (INIS)

1996-07-01

This 200-ZP-1 remedial design report presents the objectives and rationale developed for the design and implementation of the selected interim remedial measure (IRM) for the 200-ZP-1 Operable Unit, located in the 200 West Area of the Hanford Site.The IRM was chosen in accordance with the Comprehensive Environmental Response, Compensation, and Liability Act of 1980, (CERCLA), as amended by the Superfund Amendments and Reauthorization Act of 1986, the Hanford Federal Facility Agreement and Consent Order (also known as the Tri- party Agreement), and the National Oil and Hazardous Substance Pollution Contingency Plan

Direct analysis of δ13C and concentration of dissolved organic carbon (DOC) in environmental samples by TOC-IRMS

Science.gov (United States)

Kirkels, Frédérique; Cerli, Chiara; Federherr, Eugen; Kalbitz, Karsten

2014-05-01

Dissolved organic carbon (DOC) plays an important role in carbon cycling in terrestrial and aquatic systems. Stable isotope analysis (delta 13C) of DOC could provide valuable insights in its origin, fluxes and environmental fate. Precise and routine analysis of delta 13C and DOC concentration are therefore highly desirable. A promising, new system has been developed for this purpose, linking a high-temperature combustion TOC analyzer trough an interface with a continuous flow isotope ratio mass spectrometer (Elementar group, Hanau, Germany). This TOC-IRMS system enables simultaneous stable isotope (bulk delta 13C) and concentration analysis of DOC, with high oxidation efficiency by high-temperature combustion for complex mixtures as natural DOC. To give delta 13C analysis by TOC-IRMS the necessary impulse for broad-scale application, we present a detailed evaluation of its analytical performance for realistic and challenging conditions inclusive low DOC concentrations and environmental samples. High precision (standard deviation, SD predominantly TOC-IRMS and conventional EA-IRMS) were achieved by TOC-IRMS for a broad diversity of DOC solutions. This precision is comparable or even slightly better than that typically reported for EA-IRMS systems, and improves previous techniques for δ13C analysis of DOC. Simultaneously, very good precision was obtained for DOC concentration measurements. Assessment of natural abundance and slightly 13C enriched DOC, a wide range of concentrations (0.2-150 mgC/L) and injection volumes (0.05-3 ml), demonstrated good analytical performance with negligible memory effects, no concentration/volume effects and a wide linearity. Low DOC concentrations (TOC-IRMS was successfully applied to analyze DOC from diverse terrestrial, freshwater and marine environments (SD TOC-IRMS performs fast and reliable analysis of DOC concentration and δ13C in aqueous samples, without any pre-concentration/freeze-drying. Flexible usage is highlighted by

INIS information retrieval based on IBM's IRMS

International Nuclear Information System (INIS)

Gadjokov, V.; Schmid, H.; Del Bigio, G.

1975-01-01

An information retrieval system for the INIS data base is described. It allows for batch processing on an IBM/360 or /370 computer operated under OS or VS. The program package consists basically of IBM's IRMS system which was converted from DOS to OS and adapted for INIS requirements. Sections 1-9 present the system from the user's point of view, deliberately omitting all the programming details. Program descriptions with data set definitions and file formats are given in sections 10-12. (author)

Detection of petroleum contamination in river sediments from Quebec City region using GC-IRMS

International Nuclear Information System (INIS)

Rogers, K.M.; Savard, M.M.

1999-01-01

Isotopic analysis by compound specific gas chromatography-isotope ratio mass spectrometry (GC-IRMS) is used to detect and characterize petroleum pollution in surficial sediments along the St Lawrence River, near Quebec City. Unusually mature n-alkane distributions have been found in some recent intertidal sediments in the region. GC-IRMS results suggest that the n-alkanes are not derived from indigenous organic sources because they carry delta 13 C values between -30.0 and -27.0 per mille, as well as very small isotopic differences between odd and even numbered n-alkanes, which are both typically associated with petroleum products. Comparison of these sediments with bunker fuel, an oil used in the shipping industry, has shown a close isotopic correlation in some sites, which is further supported by biomarkers. Overall, the contamination has been dispersed along the river but is generally localized around the industrial region where hydrocarbon transfer from shore storage to ships takes place. This study illustrates how GC-IRMS can be used effectively in the detection and characterization of petroleum pollutants in sediments. (author)

FTIR and NDIR spectroscopies as valuable alternatives to IRMS spectrometry for the δ(13)C analysis of food.

Science.gov (United States)

Pironti, Concetta; Proto, Antonio; Camin, Federica; Cucciniello, Raffaele; Zarrella, Ilaria; Motta, Oriana

2016-11-01

The (13)C/(12)C carbon isotope ratio is a chemical parameter with many important applications in several scientific area and the technique of choice currently used for the δ(13)C determination is the isotope ratio mass spectrometry (IRMS). This latter is highly accurate (0.1‰) and sensitive (up to 0.01‰), but at the same time expensive and complex. The objective of this work was to assess the reliability of FTIR and NDIRS techniques for the measurement of carbon stable isotope ratio of food sample, in comparison to IRMS. IRMS, NDIRS and FTIR were used to analyze samples of food, such as oil, durum, cocoa, pasta and sugar, in order to determine the natural abundance isotopic ratio of carbon in a parallel way. The results were comparable, showing a close relationship among the three techniques. The main advantage in using FTIR and NDIRS is related to their cheapness and easy-to-operate in comparison to IRMS. Copyright © 2016 Elsevier B.V. All rights reserved.

δ15N measurement of organic and inorganic substances by EA-IRMS: a speciation-dependent procedure.

Science.gov (United States)

Gentile, Natacha; Rossi, Michel J; Delémont, Olivier; Siegwolf, Rolf T W

2013-01-01

Little attention has been paid so far to the influence of the chemical nature of the substance when measuring δ(15)N by elemental analysis (EA)-isotope ratio mass spectrometry (IRMS). Although the bulk nitrogen isotope analysis of organic material is not to be questioned, literature from different disciplines using IRMS provides hints that the quantitative conversion of nitrate into nitrogen presents difficulties. We observed abnormal series of δ(15)N values of laboratory standards and nitrates. These unexpected results were shown to be related to the tailing of the nitrogen peak of nitrate-containing compounds. A series of experiments were set up to investigate the cause of this phenomenon, using ammonium nitrate (NH(4)NO(3)) and potassium nitrate (KNO(3)) samples, two organic laboratory standards as well as the international secondary reference materials IAEA-N1, IAEA-N2-two ammonium sulphates [(NH(4))(2)SO(4)]-and IAEA-NO-3, a potassium nitrate. In experiment 1, we used graphite and vanadium pentoxide (V(2)O(5)) as additives to observe if they could enhance the decomposition (combustion) of nitrates. In experiment 2, we tested another elemental analyser configuration including an additional section of reduced copper in order to see whether or not the tailing could originate from an incomplete reduction process. Finally, we modified several parameters of the method and observed their influence on the peak shape, δ(15)N value and nitrogen content in weight percent of nitrogen of the target substances. We found the best results using mere thermal decomposition in helium, under exclusion of any oxygen. We show that the analytical procedure used for organic samples should not be used for nitrates because of their different chemical nature. We present the best performance given one set of sample introduction parameters for the analysis of nitrates, as well as for the ammonium sulphate IAEA-N1 and IAEA-N2 reference materials. We discuss these results considering the

Forensic analysis of explosives using isotope ratio mass spectrometry (IRMS)--part 1: instrument validation of the DELTAplusXP IRMS for bulk nitrogen isotope ratio measurements.

Science.gov (United States)

Benson, Sarah J; Lennard, Christopher J; Hill, David M; Maynard, Philip; Roux, Claude

2010-01-01

A significant amount of research has been conducted into the use of stable isotopes to assist in determining the origin of various materials. The research conducted in the forensic field shows the potential of isotope ratio mass spectrometry (IRMS) to provide a level of discrimination not achievable utilizing traditional forensic techniques. Despite the research there have been few, if any, publications addressing the validation and measurement uncertainty of the technique for forensic applications. This study, the first in a planned series, presents validation data for the measurement of bulk nitrogen isotope ratios in ammonium nitrate (AN) using the DELTA(plus)XP (Thermo Finnigan) IRMS instrument equipped with a ConFlo III interface and FlashEA 1112 elemental analyzer (EA). Appropriate laboratory standards, analytical methods and correction calculations were developed and evaluated. A validation protocol was developed in line with the guidelines provided by the National Association of Testing Authorities, Australia (NATA). Performance characteristics including: accuracy, precision/repeatability, reproducibility/ruggedness, robustness, linear range, and measurement uncertainty were evaluated for the measurement of nitrogen isotope ratios in AN. AN (99.5%) and ammonium thiocyanate (99.99+%) were determined to be the most suitable laboratory standards and were calibrated against international standards (certified reference materials). All performance characteristics were within an acceptable range when potential uncertainties, including the manufacturer's uncertainty of the technique and standards, were taken into account. The experiments described in this article could be used as a model for validation of other instruments for similar purposes. Later studies in this series will address the more general issue of demonstrating that the IRMS technique is scientifically sound and fit-for-purpose in the forensic explosives analysis field.

Determination of cell cycle phases in live B16 melanoma cells using IRMS.

Science.gov (United States)

Bedolla, Diana E; Kenig, Saša; Mitri, Elisa; Ferraris, Paolo; Marcello, Alessandro; Grenci, Gianluca; Vaccari, Lisa

2013-07-21

The knowledge of cell cycle phase distribution is of paramount importance for understanding cellular behaviour under normal and stressed growth conditions. This task is usually assessed using Flow Cytometry (FC) or immunohistochemistry. Here we report on the use of FTIR microspectroscopy in Microfluidic Devices (MD-IRMS) as an alternative technique for studying cell cycle distribution in live cells. Asynchronous, S- and G0-synchronized B16 mouse melanoma cells were studied by running parallel experiments based on MD-IRMS and FC using Propidium Iodide (PI) staining. MD-IRMS experiments have been done using silicon-modified BaF2 devices, where the thin silicon layer prevents BaF2 dissolution without affecting the transparency of the material and therefore enabling a better assessment of the Phosphate I (PhI) and II (PhII) bands. Hierarchical Cluster Analysis (HCA) of cellular microspectra in the 1300-1000 cm(-1) region pointed out a distribution of cells among clusters, which is in good agreement with FC results among G0/G1, S and G2/M phases. The differentiation is mostly driven by the intensity of PhI and PhII bands. In particular, PhI almost doubles from the G0/G1 to G2/M phase, in agreement with the trend followed by nucleic acids during cellular progression. MD-IRMS is then proposed as a powerful method for the in situ determination of the cell cycle stage of an individual cell, without any labelling or staining, which gives the advantage of possibly monitoring specific cellular responses to several types of stimuli by clearly separating the spectral signatures related to the cellular response from those of cells that are normally progressing.

Relações familiares e habilidades sociais de irmãos de indivíduos com transtorno do espectro autístico: estudo comparativo

OpenAIRE

Feltrin, Aline Beatriz Silva [UNESP

2007-01-01

Por meio do convívio diário, os irmãos podem adquirir habilidades sociais e cognitivas fundamentais para o desenvolvimento social saudável. As contingências que configuram estas relações podem ser diferentes daquelas a que estão submetidos irmãos de crianças com desenvolvimento normal ou irmãos de indivíduos com outros tipos de deficiência, o que justifica estudos envolvendo interações entre irmãos de crianças com Transtorno do Espectro Autístico (TEA). O acervo de investigações desenvolvidas...

Ser Irmão de uma Pessoa Surda: Relatos da Infância à Fase Adulta

Directory of Open Access Journals (Sweden)

Juliana Archiza YAMASHIRO

Full Text Available RESUMO: o objetivo do presente estudo foi analisar a experiência de irmãos de pessoas surdas acerca de sua história de vida e das implicações da deficiência nos relacionamentos fraternos. Tratou-se de um estudo exploratório, de abordagem qualitativa, que contou com a participação de cinco irmãos de pessoas surdas com idade entre 31 a 44 anos. Para a coleta de dados foram utilizados os seguintes instrumentos: questionário de identificação e roteiro de entrevista em profundidade. Os dados obtidos foram analisados a partir do modelo de produções de sentido das práticas discursivas. Os principais resultados apontaram que a dificuldade de comunicação entre os participantes e seus irmãos surdos repercutiu em questões nos relacionamentos desde a infância até a fase adulta. Considera-se que as questões inerentes à deficiência trouxeram consequências a todos os membros da família, em especial nos quesitos relacionamentos e comunicação e que disponibilizar atenção especializada aos pais e irmãos destas pessoas auxiliaria no manejo das situações vinculadas à deficiência e fortalecimento dos vínculos familiares.

Taking the atmosphere's pulse: The application of GC-IRMS to stable isotopes in atmospheric trace gases

International Nuclear Information System (INIS)

Lowe, D.C.; Ferretti, D.J.; Francey, R.J.; Allison, C.E.

2001-01-01

Since the industrial revolution, the abundance of many atmospheric trace gases has changed significantly. This is of concern because many of these trace species play a fundamental role in determining physical and chemical properties of the atmosphere important for maintaining life on earth. The impacts of the changes have been studied by a combination of analytical and theoretical modelling techniques. Stable isotope measurements made by conventional dual inlet IRMS for example, have provided valuable constraints on the budgets and removal mechanisms of key atmospheric trace gases. Unfortunately, in most cases, the application of these methods has been limited, because large air samples and cumbersome off line processing techniques are required to pre-concentrate enough gas for analysis. GC-IRMS offers a very attractive alternative because it combines on line processing with air sample size requirements typically 1000 times less than used in conventional techniques. In this article we focus on the requirements imposed on GC-IRMS by some of the current applications in atmospheric trace gas research. In addition, we examine some of the analytical and calibration aspects of the method applied to this kind of work. We finish with a summary of some of the comparative advantages and disadvantages of the GC-IRMS technique and some suggestions for future research using the method applied to specific atmospheric trace gases. (author)

Scalable Integrated Region-Based Image Retrieval Using IRM and Statistical Clustering.

Science.gov (United States)

Wang, James Z.; Du, Yanping

Statistical clustering is critical in designing scalable image retrieval systems. This paper presents a scalable algorithm for indexing and retrieving images based on region segmentation. The method uses statistical clustering on region features and IRM (Integrated Region Matching), a measure developed to evaluate overall similarity between images…

A função fraterna e as vicissitudes de ter e ser um irmão

Directory of Open Access Journals (Sweden)

Rebeca Goldsmid

2007-12-01

Full Text Available Apesar da importância do irmão na constituição do sujeito,somente por volta do ano 2000, os autores contemporâneospassaram a mostrar um interesse maior pelo estudo da relaçãofraterna. Grande parte desses estudos se dedica mais à competiçãoe à rivalidade entre os irmãos do que à boa convivência e àsolidariedade. Em nossa revisão teórica, realizada na abordagempsicanalítica, iniciamos pelos clássicos – Freud, Klein e Adler – eprosseguimos com os autores contemporâneos, fazendo um estudosobre a dinâmica da relação fraterna, focalizando seus aspectos decompetição e de rivalidade bem como os de solidariedade e decompanheirismo. Constatamos, assim, a importância da fratriana construção da subjetividade dos irmãos.

Dual element ((15)N/(14)N, (13)C/(12)C) isotope analysis of glyphosate and AMPA by derivatization-gas chromatography isotope ratio mass spectrometry (GC/IRMS) combined with LC/IRMS.

Science.gov (United States)

Mogusu, Emmanuel O; Wolbert, J Benjamin; Kujawinski, Dorothea M; Jochmann, Maik A; Elsner, Martin

2015-07-01

To assess sources and degradation of the herbicide glyphosate [N-(phosphonomethyl) glycine] and its metabolite AMPA (aminomethylphosphonic acid), concentration measurements are often inconclusive and even (13)C/(12)C analysis alone may give limited information. To advance isotope ratio analysis of an additional element, we present compound-specific (15)N/(14)N analysis of glyphosate and AMPA by a two step derivatization in combination with gas chromatography/isotope ratio mass spectrometry (GC/IRMS). The N-H group was derivatized with isopropyl chloroformate (iso-PCF), and remaining acidic groups were subsequently methylated with trimethylsilyldiazomethane (TMSD). Iso-PCF treatment at pH 10 indicated decomposition of the derivative. At pH 10, and with an excess of iso-PCF by 10-24, greatest yields and accurate (15)N/(14)N ratios were obtained (deviation from elemental analyzer-IRMS: -0.2 ± 0.9% for glyphosate; -0.4 ± 0.7% for AMPA). Limits for accurate δ(15)N analysis of glyphosate and AMPA were 150 and 250 ng injected, respectively. A combination of δ(15)N and δ(13)C analysis by liquid chromatography/isotope ratio mass spectrometry (LC/IRMS) (1) enabled an improved distinction of commercial glyphosate products and (2) showed that glyphosate isotope values during degradation by MnO2 clearly fell outside the commercial product range. This highlights the potential of combined carbon and nitrogen isotopes analysis to trace sources and degradation of glyphosate.

Caretaking behavior among siblings in children's shelters Comportamento de cuidado entre irmãos em instituição de abrigo

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Lília Iêda Chaves Cavalcante

2012-01-01

Full Text Available This study analyzed 742 events involving caretaking behavior among sheltered children with or without siblings in the same institution. Statistical tests were used for intergroup evaluation in comparison to focal subjects. Children with siblings showed a greater number of those behaviors and they were primarily directed to non-sibling peers (roommates or adults (caretakers. The study also revealed that the caretaking behavior was more frequent in the group of children with siblings in the institution whereas those without siblings showed a more affective contact and behaviors directed more to adults than to peers. It was concluded that the caretaking behavior is present among siblings, but it assumes particular shapes because of the complex social dynamics that characterize the research environment.Este estudo analisou 742 eventos envolvendo comportamento de cuidado entre crianças abrigadas com e sem irmão na mesma instituição. Foram aplicados testes estatísticos para avaliação intergrupal na comparação entre os sujeitos focais. As crianças com irmão manifestaram a maior proporção desses comportamentos e foram dirigidos principalmente a parceiros não-Irmãos (companheiros de dormitório ou adultos (cuidadores. O estudo revelou ainda que o comportamento Brincar de cuidar foi mais freqüente no grupo de crianças Com Irmão na instituição enquanto que entre os participantes Sem Irmão predominou Estabelecer contato afetuoso e comportamentos direcionados mais a adultos do que aos pares. Conclui-se que o comportamento de cuidado está presente entre irmãos, mas assume formas particulares em razão da complexa dinâmica social que caracteriza o ambiente pesquisado.

2013 Higher Education Summit/SUS Data Workshop Proceedings. Session: IRM Data Workshop

Science.gov (United States)

Board of Governors, State University System of Florida, 2013

2013-01-01

Information Resource Management--State University System of Florida (IRM-SUS) is the primary collector and provider of data concerning state universities that is used to make sound education policy decisions. The office provides technical assistance to those using the information, state and federal reporting support, those supplying information,…

A case study on the application of isotope ratio mass spectrometry (IRMS) in determining the provenance of a rock used in an alleged nickel switching incident.

Science.gov (United States)

Roelofse, F; Horstmann, U E

2008-01-15

The application of isotope ratio mass spectrometry (IRMS) in forensic science to establish the provenance of a range of questioned substances including soils, drugs, explosives, currency, ivory and rhino horn has been widely documented. The present study wishes to highlight the applicability of IRMS and specifically stable carbon IRMS in determining the provenance of a carbonate rock that was switched for nickel metal exported from South Africa to Israel. The technique employed effectively argued against a South African origin for the rock whilst simultaneously supporting an Israeli origin, enabling investigators to focus their attention accordingly. The study represents the first documented instance known to the authors where IRMS has been employed in the forensic geo-location of a rock.

Measurement of organic carbon stable isotope composition of different soil types by EA-IRMS system

International Nuclear Information System (INIS)

Qi Biao; Ding Lingling; Cui Jiehua; Wang Yanhong

2009-01-01

Element analyzer-isotope ratio mass spectrometers (EA-IRMS) is a rapid and precise method for measuring stable carbon isotope. Pure CO 2 reference gas was calibrated via international standard-Urea, and the δ 13 C us PDB value of pure CO 2 is (-29.523 ± 0.0181)%. Stability and linearity of the EA-IRMS system, precision of δ 13 C measurement for samples were tested through experimental comparison. Moreover, determination method of organic carbon stable isotope in soil was based on the system. The EA-IRMS system had well linearity when ion intensity ranged from 1.0 to 7.0V, and it excelled the total linearity when the ion intensity was from 1.5 to 5.0V, and the accurate result of δ 13 C for sample analysis could be obtained with precision of 0.015%. If carbon content in sample is more than 5μg, the requirement for analyzing accurate result of δ 13 C could be achieved. The organic carbon stable isotope was measured in 18 different types soil samples, the average natural abundance of 13 C was 1.082%, and the organic carbon stable isotope composition was significantly different among different type soils. (authors)

Hyphomycetes from water and soil at the Dois Irmãos Forest Reserve, Recife, Pernambuco State, Brazil

OpenAIRE

Cavalcanti, Marilene da Silva; Milanez, Adauto Ivo

2007-01-01

(Hyphomycetes isolados da água e do solo, da Reserva Florestal de Dois Irmãos, Recife, PE, Brasil). Visando ampliar o conhecimento sobre a diversidade de fungos em ambientes aquáticos, coletas da água e do solo das margens dos açudes do Vale do Prata e do Meio foram efetuadas na Reserva Florestal de Dois Irmãos, Recife, Estado de Pernambuco. Dentre outras, foram isoladas cinco espécies pouco comuns de Hyphomycetes. As amostras de água foram coletadas abaixo da lâmina d'água e as de solo nas m...

Dose-dependent testosterone sensitivity of the steroidal passport and GC-C-IRMS analysis in relation to the UGT2B17 deletion polymorphism.

Science.gov (United States)

Strahm, Emmanuel; Mullen, Jenny E; Gårevik, Nina; Ericsson, Magnus; Schulze, Jenny J; Rane, Anders; Ekström, Lena

2015-01-01

The newly implemented Steroid Module of the Athlete Biological Passport has improved doping tests for steroids. A biomarker included in this passport is the urinary testosterone glucuronide to epitestosterone glucuronide (T/E) ratio, a ratio greatly affected by a deletion polymorphism in UGT2B17. Suspect urine doping tests are further analyzed with gas chromatography-combustion-isotope ratio mass spectrometry (GC-C-IRMS) to determine the origin of the androgen. In this study, we investigated the sensitivity of the steroidal module and the IRMS analysis, in subjects administered with three doses of testosterone enanthate (500, 250, and 125 mg), in relation to the UGT2B17 polymorphism. All subjects carrying the UGT2B17 enzyme reached the traditionally used threshold, a T/E ratio of 4, after all three administered doses, whereas none of the subjects devoid of this enzyme reached a T/E of 4. On the other hand, using the athlete biological passport and IRMS analysis, all three doses could be detected to a high degree of sensitivity. The concentrations of all steroids included in the steroidal module were dose dependently increased, except for epitestosterone which decreased independent of dose. The decrease in epitestosterone was significantly associated with circulatory levels of testosterone post dose (rs =0.60 and p=0.007). In conclusion, these results demonstrate that administration of a single dose of 125-500 mg testosterone enanthate could be detected using the athlete biological passport, together with IRMS. Since IRMS is sensitive to testosterone doping independent of UGT2B17 genotype, also very small changes in the steroidal passport should be investigated with IRMS. Copyright © 2015 John Wiley & Sons, Ltd.

A participação da irmã Mathilde Nina na construção histórica da ABEn

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Maria Regina Marques Bezerra

2001-06-01

Full Text Available Estudo de cunho histórico-social, cujo objeto é a participação da Irmã Mathilde Nina no processo histórico da Associação Brasileira de Enfermagem (ABEn, como representante da Companhia das Filhas da Caridade. Objetivo: discutir o advento da inserção dessa Irmã na Associação Brasileira de Enfermagem como uma forma de difusão da influência católica. Recorte temporal: 1939 a 1950. Fontes primárias: documentos escritos e depoimento de pessoas que tenham convivido com Mathilde Nina. O método é dialético, e a discussão dos achados fundamenta-se no pensamento de Pierre Bourdieu. As Irmãs da Caridade fizeram, no Brasil, um movimento de inserção na educação formal. Tal evento foi conseqüência do Decreto 20.109/31. Como primeira representante da Companhia a se diplomar, a Irmã Nina possuía um capital que a legitimava nas várias instâncias da enfermagem; sua inserção na ABEn é mais uma das formas de difusão da ideologia católica.

Implementation of AICAR analysis by GC-C-IRMS for anti-doping purposes.

Science.gov (United States)

Buisson, C; Frelat, C; Mongongu, C; Martinat, N; Audran, M

2017-11-01

AICAR (5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside), is a naturally occurring substance which is part to the World Anti-Doping Agency (WADA) Prohibited List. It is claimed to improve physical performance when administered as a supplement. As for other endogenous compounds such as steroids, the gas chromatography-combustion-isotope ratio mass spectrometry (GC-C-IRMS) analysis remains an efficient tool to differentiate endogenous substances from exogenous ones. A protocol was described in the literature for the analysis of AICAR by GC-C-IRMS. The aim of the present study was to implement this protocol in our laboratory and to propose solutions to avoid the difficulties encountered. The first point discussed in this study is the derivatization step. Due to the structure of the AICAR molecule, conventional derivatization for GC-C-IRMS such as acetylation could not be applied and silylation was preferred. The improvement of the derivatives stability was achieved thanks to several derivatization conditions tested. This adjustment led to a reproducible derivatization pattern with the 3-TMS form as major derivative product. The second point discussed in this study is the diminution of extracts' background noise. Indeed, the implementation of the published protocol was not easy due to high performance liquid chromatography (HPLC) problems encountered when concentrated urine was injected into our system. Also, too many interferences in the endogenous reference compound fractions were observed. The addition of both a wash step before the HPLC purification and a HPLC purification step for the endogenous reference compound (ERC) fraction allowed us to increase the robustness of the method. This study presents the modified protocol compared to the original protocol as well as the evaluation of the whole method performances. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

GC-C-IRMS in routine doping control practice: 3 years of drug testing data, quality control and evolution of the method.

Science.gov (United States)

Polet, Michael; Van Eenoo, Peter

2015-06-01

In order to detect the misuse of endogenous anabolic steroids, doping control laboratories require methods that allow differentiation between endogenous steroids and their synthetic copies. Gas chromatography combustion isotope ratio mass spectrometry (GC-C-IRMS) is capable of measuring the carbon isotope ratio of urinary steroids and this allows differentiation between both. GC-C-IRMS and its application to doping control has evolved a lot during the last decade and so have the World Anti-Doping Agency (WADA) technical documents that describe how GC-C-IRMS should be applied. Especially the WADA technical document of 2014 introduced a number of obligatory quality controls and a fixed methodology that should be used by all the doping control laboratories. This document imposed more uniform methods between the laboratories in order to decrease the interlaboratory standard deviation and acquire similar results for the analysis of the same urine samples. In this paper, 3 years of drug testing data of our GC-C-IRMS method in routine doping control practice is described, with an emphasis on the new WADA technical document and its implementation. Useful data for other doping control laboratories is presented focussing on general method setup, quality control and data collected from routine samples. The paper concentrates on how IRMS results shift or remain similar by switching to the 2014 WADA technical document and gives insight in a straightforward approach to calculate the measurement uncertainty.

A simplified procedure for GC/C/IRMS analysis of underivatized 19-norandrosterone in urine following HPLC purification.

Science.gov (United States)

de la Torre, Xavier; Colamonici, Cristiana; Curcio, Davide; Molaioni, Francesco; Pizzardi, Marta; Botrè, Francesco

2011-04-01

Nandrolone and/or its precursors are included in the World Anti-doping Agency (WADA) list of forbidden substances and methods and as such their use is banned in sport. 19-Norandrosterone (19-NA) the main metabolite of these compounds can also be produced endogenously. The need to establish the origin of 19-NA in human urine samples obliges the antidoping laboratories to use isotope ratio mass spectrometry (IRMS) coupled to gas chromatography (GC/C/IRMS). In this work a simple liquid chromatographic method without any additional derivatization step is proposed, allowing to drastically simplify the urine pretreatment procedure, leading to extracts free of interferences permitting precise and accurate IRMS analysis. The purity of the extracts was verified by parallel analysis by gas chromatography coupled to mass spectrometry with GC conditions identical to those of the GC/C/IRMS assay. The method has been validated according to ISO17025 requirements (within assay precision of ±0.3‰ and between assay precision of ±0.4‰). The method has been tested with samples obtained after the administration of synthetic 19-norandrostenediol and samples collected during pregnancy where 19-NA is known to be produced endogenously. Twelve drugs and synthetic standards able to produce through metabolism 19-NA have shown to present δ(13)C values around -29‰ being quite homogeneous (-28.8±1.5; mean±standard deviation) while endogenously produced 19-NA has shown values comparable to other endogenous produced steroids in the range -21 to -24‰ as already reported. The efficacy of the method was tested on real samples from routine antidoping analyses. Copyright © 2011 Elsevier Inc. All rights reserved.

Compound-specific isotope analysis of light elements using gas chromatography/combustion/isotope ratio mass spectrometry (GC/C/IRMS) and its application to geochemistry

International Nuclear Information System (INIS)

Naraoka, Hiroshi; Yamada, Keita; Matsumoto, Kohei; Ishiwatari, Ryoshi

1997-01-01

Compound-specific isotope analysis has been developed recently using gas chromatography/combustion/mass spectrometry (GC/C/IRMS). This paper summarizes principles and progress of GC/C/IRMS, and reviews recent some important works using this new method. GC/C/IRMS is a novel tool for (1) biomarker analysis in sediments and living matter, (2) paleoenvironment analysis including reconstruction of ancient biogeochemical processes, (3) geochemical cycle study of organic compounds in a terrestrial-marine system, (4) evaluation of maturity and diagenesis of organic matter including petroleum formation, (5) ecological analysis, (6) evaluation of anthropologenic pollution in environment, (7) detection of extraterrestrial organic compounds and the formation mechanism study, (8) tracer studies in environment. (author)

Methods in the use of GC/C/IRMS for the analysis of biochemical and pollutant isotope signatures of compounds

International Nuclear Information System (INIS)

Macko, S.A.; Engel, M.H.

2001-01-01

The potential for application of GC/C/IRMS analysis to any multitude of environmental, ecological or biochemical research areas is only beginning to be realized. Extension of compound-specific isotope analytical data derived from modern organisms and settings to yield interpretations of ancient depositional environments certainly appears possible. Further application of GC/C/IRMS approaches to understand the cycling of carbon and nitrogen, the identification and alteration of pollutants, or resolve metabolic relationships between compounds in living or extinct organisms are all within the scope of future research. (author)

Estudo Exploratório sobre a Violência entre Irmãos em Portugal

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Inês Carvalho Relva

2014-01-01

Full Text Available A violência entre irmãos é uma das formas mais comuns de violência familiar. Este estudo pretendeu caracterizar este problema em Portugal, numa amostra de 588 estudantes universitários. Os diferentes tipos de violência (física, psicológica e sexual foram avaliados com as "Revised Conflict Tactics Scales - Sibling Version". Procedeu-se a análises descritivas exploratórias das distribuições das principais variáveis, recorreu-se ao teste do χ2 e a análises de covariância múltipla. Os resultados indicaram que a violência entre irmãos é muito frequente no início da adolescência; os rapazes perpetraram significativamente mais atos de violência física (p <0,001 e sexual (p <0,05 do que as raparigas, mas foram também, física (p <0,001 e sexualmente (p <0,05, mais vitimizados. Também as díades masculinas apresentaram níveis de violência física e sexual significativamente superiores aos de todas as outras díades, indicando claramente a reciprocidade do fenómeno. Os resultados foram discutidos segundo perspetivas de 'normalização de agressões' (dissonância cognitiva; Hardy, Beers, Burguess, & Taylor, 2010 e do 'ciclo de violência', as quais explicam a manutenção de comportamentos abusivos entre irmãos e a sua possível transferência para outras relações.

Dois pares de irmãos com artrite idiopática juvenil (AIJ: relato de casos

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Teresa Cristina M.V. Robazzi

2015-02-01

Full Text Available Relato de casos de ocorrência de Artrite Idiopática Juvenil (AIJ em dois pares de irmãos acompanhados no serviço de reumatologia pediátrica da Universidade Federal da Bahia. O envolvimento genético na patogênese da AIJ está claro e o risco de recorrência entre irmãos corrobora esta contribuição. Um importante marco dessa descoberta envolve a confirmação da contribuição dos polimorfismos do complexo principal de histocompatibilidade (MHC na susceptibilidade ao desenvolvimento da AIJ. Apesar de muitos progressos, os inúmeros estudos existentes ainda não são capazes de explicar diversos mecanismos implícitos na patogênese da AIJ.

Drug testing data from the 2007 Pan American Games: delta13C values of urinary androsterone, etiocholanolone and androstanediols determined by GC/C/IRMS.

Science.gov (United States)

Aguilera, Rodrigo; Chapman, Thomas E; Pereira, Henrique; Oliveira, Giselle C; Illanes, Renata P; Fernandes, Telma F; Azevedo, Débora A; Neto, Francisco Aquino

2009-07-01

The main purpose of this article is to show the application of the CG/C/IRMS in real time during competition in the steroid confirmation analysis. For this reason, this paper summarizes the results obtained from the doping control analysis during the period of the 2007 Pan American Games held in Rio de Janeiro, Brazil. Approximately 5600 athletes from 42 different countries competed in the games. Testing was performed in accordance to World Anti-Doping Agency (WADA) technical note for prohibited substances. This paper reports data where abnormal urinary steroid profiles, have been found with the screening procedures. One 8 mL urine sample was used for the analysis of five steroid metabolites with two separate analyses by gas chromatography/combustion/isotope ratio mass spectrometry (GC/C/IRMS). Urine samples were submitted to GC/C/IRMS for confirmation analysis to determine the (13)C/(12)C ratio of selected steroids. Fifty-seven urine samples were analyzed by GC/C/IRMS and the delta(13)C values ( per thousand) of androsterone, etiocholanolone, 5beta-androstane-3alpha, 17beta-diol (5beta-diol), 5alpha-androstane-3alpha, 17beta-diol (5alpha-diol) and 5beta-pregnane-3alpha, 20alpha-diol (5beta-pdiol), the endogenous reference compound are presented. One urine sample with a testosterone/epitestosterone (T/E) ratio of 4.7 was confirmed to be positive of doping by GC/C/IRMS analysis. The delta values of 5beta-diol and 5alpha-diol were 3.8 and 10.8, respectively, compared to the endogenous reference compound 5beta-pdiol, which exceeded the WADA limit of 3 per thousand. The results obtained by CG/C/IRMS confirmation analyses, in suspicious samples, were conclusive in deciding whether or not a doping steroid violation had occurred.

Water stable isotope measurements of Antarctic samples by means of IRMS and WS-CRDS techniques

Science.gov (United States)

Michelini, Marzia; Bonazza, Mattia; Braida, Martina; Flora, Onelio; Dreossi, Giuliano; Stenni, Barbara

2010-05-01

of the sample in the box. In the WS-CRDS the path of laser is longer, producing higher-sensitivity measurements. The instrument is paired with an autosampler and can be used without it and the vaporizer to analyze directly the isotopic composition of the water vapour in the atmosphere. In addition, the instrument can be moved from the laboratory and also used for outdoor measurements. The more important improvements over traditional IRMS techniques are that WS-CRDS needs less sample in order to perform the analysis (water equilibration techniques) and the analyses are faster. Coversely, memory effects may affect the measurements so there is the need to increase the number of injection to have a high precision measurement. The laboratory of Isotope Geochemistry of the Department of Geosciences has recently acquired a WS-CRDS system from PICARRO. The isotopic data obtained with this new method have been compared with the ones obtained by means of IRMS methods. An HDO device coupled with a Thermo Finnigan Delta Plus Advantage mass spectrometer has been used, using the well know CO2 and H2/water equilibration technique. At the moment of the writing of the abstract the mean difference between the values obtained using PICARRO and using the traditional IRMS method is of the order of 0.1 per mil for the ratio 18O/16O and 1.00 per mil for the ratio D/H, but further measurements are currently underway. O'Keef A., Deacon D.A.G., 1988. Cavity ring-down optical spectrometer for absorption measurements using pulsed laser sources, Rev. Sci. Instrum., 59, 2544.

Era uma vez dois irmãos...

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Marcus V. Mazzari

2011-01-01

Full Text Available Este ensaio aborda a narrativa Grimms Wörter [Palavras de Grimm], publicada por Günter Grass em agosto de 2010, pouco antes de completar 83 anos. Wilhelm e Jacob Grimm são suas personagens principais e o tema gira em torno dos esforços despendidos pelos irmãos para elaborar um grande dicionário da língua alemã, concluí-do apenas em 1961 com a publicação do 32º volume. Organizando os capítulos do livro (e também a estrutura narrativa pelas letras do alfabeto, Grass presta comovida homenagem ao trabalho filológico de Wilhelm e Jacob Grimm, ao mesmo tempo que faz uma declaração de amor à língua alemã. Ao mostrar ainda de que modo 123 anos da história alemã se refletem na intrincada gênese do dicionário, o narrador toma episódios fundamentais da vida dos irmãos Grimm como ensejo para reconstituir estações de sua própria biografia política e artística. Na perspectiva desse entrelaçamento de trajetórias, o ensaio privilegia uma passagem do capítulo dedicado à letra "D" (de Däumling: Pequeno Polegar, em alemão para ressaltar a influência que um dos mais célebres heróis dos irmãos Grimm teve sobre a concepção de Oskar Matzerath, o eu narrador do romance O tambor de lata. Estabelece-se assim um arco entre a narrativa Grimms Wörter e o romance que proporcionou notoriedade mundial ao jovem Günter Grass.This essay discusses the narrative Grimms Wörter [Words of Grimm] published by Günter Grass in August 2010, just before his eighty-third birthday. Wilhelm and Jacob Grimm are his main characters, and the theme centres on the efforts of the brothers to elaborate a great dictionary of the German language, which was only completed in 1961 with the publication of the thirty-second volume. Organizing the chapters of the book (and also the narrative structure by the letters of the alphabet, Grass makes a moving tribute to the philological work of Wilhelm and Jacob Grimm and a declaration of love for the German

Hyphomycetes isolados da água e do solo da Reserva Florestal de Dois Irmãos, Recife, PE, Brasil

OpenAIRE

Cavalcanti,Marilene da Silva; Milanez,Adauto Ivo

2007-01-01

(Hyphomycetes isolados da água e do solo, da Reserva Florestal de Dois Irmãos, Recife, PE, Brasil). Visando ampliar o conhecimento sobre a diversidade de fungos em ambientes aquáticos, coletas da água e do solo das margens dos açudes do Vale do Prata e do Meio foram efetuadas na Reserva Florestal de Dois Irmãos, Recife, Estado de Pernambuco. Dentre outras, foram isoladas cinco espécies pouco comuns de Hyphomycetes. As amostras de água foram coletadas abaixo da lâmina d'água e as de solo nas m...

MHD model of magnetosheath flow: comparison with AMPTE/IRM observations on 24 October, 1985

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C. J. Farrugia

1998-05-01

Full Text Available We compare numerical results obtained from a steady-state MHD model of solar wind flow past the terrestrial magnetosphere with documented observations made by the AMPTE/IRM spacecraft on 24 October, 1985, during an inbound crossing of the magnetosheath. Observations indicate that steady conditions prevailed during this about 4 hour-long crossing. The magnetic shear at spacecraft entry into the magnetosphere was 15°. A steady density decrease and a concomitant magnetic field pile-up were observed during the 40 min interval just preceding the magnetopause crossing. In this plasma depletion layer (1 the plasma beta dropped to values below unity; (2 the flow speed tangential to the magnetopause was enhanced; and (3 the local magnetic field and velocity vectors became increasingly more orthogonal to each other as the magnetopause was approached (Phan et al., 1994. We model parameter variations along a spacecraft orbit approximating that of AMPTE/IRM, which was at slightly southern GSE latitudes and about 1.5 h post-noon Local Time. We model the magnetopause as a tangential discontinuity, as suggested by the observations, and take as input solar wind parameters those measured by AMPTE/IRM just prior to its bow shock crossing. We find that computed field and plasma profiles across the magnetosheath and plasma depletion layer match all observations closely. Theoretical predictions on stagnation line flow near this low-shear magnetopause are confirmed by the experimental findings. Our theory does not give, and the data on this pass do not show, any localized density enhancements in the inner magnetosheath region just outside the plasma depletion layer.Key words. Steady-state magnetosheath · Plasma depletion layer · Stagnation line flow

O impacto da deficiência nos irmãos: histórias de vida Impact of disability in siblings: life stories

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Alcione Aparecida Messa

2010-03-01

Full Text Available Quando uma criança nasce com deficiência, a expectativa da família necessita ser revista, pois se trata de uma situação inesperada, exigindo o ajuste às mudanças de planos. Devido ao significado do relacionamento fraterno, mudanças na saúde e no funcionamento de um irmão irão afetar os outros. As relações com um irmão deficiente dependerão das características da deficiência, além do significado compartilhado na família. O objetivo desta pesquisa foi analisar as repercussões da deficiência para os irmãos, investigando os sentimentos e reações que permeiam as vivências desses indivíduos. Realizouse um grupo de discussão. Os resultados apontaram que cada indivíduo dá significado a vivência com um irmão deficiente segundo seus recursos e história de vida. Os irmãos apresentaram sentimentos negativos como raiva, vergonha e culpa e também ganhos como maturidade, independência e altruísmo. Pode-se concluir que o impacto da deficiência nos irmãos compreende vivências negativas e positivas e que, portanto, deve ser considerado segundo uma rede de influências e peculiaridades intrínsecas das relações familiares. Evidencia-se a necessidade de que esses irmãos sejam assistidos de forma adequada, visando à ampliação dos recursos disponíveis.When a disabled child is born all the family's expectations need to be reviewed because it is an unexpected situation and needs the family system to be adjusted to the new situation. Due to the meaning that sibling relations acquire during lifetime, changes in health and functioning of a sibling will affect the others. Relations with a disabled sibling will depend on features of disability as well as its meaning shared by the family. The aim of this research was to analyze the manifestation of disability for siblings of disabled people, investigating feelings and reactions that pervade their experiences. A discussion group of siblings was created. Results indicated that each

Laser assisted ratio analysis - An alternative to GC/IRMS for CO2

International Nuclear Information System (INIS)

Murnick, D.E.

2001-01-01

A new technique for laser based analysis of carbon isotope ratios, with the acronym LARA, based on large isotope shifts in molecular spectra, the use of fixed frequency isotopic lasers, and sensitive detection via the laser optogalvanic effect is reviewed and compared with GC/IRMS for carbon dioxide in specific applications. The possibility for development of new classes of isotope ratio measurement systems with LARA is explored. (author)

Implementation of Enhanced Integrated Retail Module (IRM) Installation at Ft. Jackson Clothing Initial Issue Point (CIIP), South Carolina

National Research Council Canada - National Science Library

Perrin, Richard A; Fraser, Carol; DeLoach, Doug

2006-01-01

... military clothing inventory. The Enhanced IRM solution brought improvements to accountability of warehouse inventory transactions in VIM/Wholesale Local, improved the efficiency and accountability of sales...

Laser ablation-combustion-GC-IRMS--a new method for online analysis of intra-annual variation of delta13C in tree rings.

Science.gov (United States)

Schulze, Brigit; Wirth, Christian; Linke, Petra; Brand, Willi A; Kuhlmann, Iris; Horna, Viviana; Schulze, Ernst-Detlef

2004-11-01

We present a new, rapid method for high-resolution online determination of delta13C in tree rings, combining laser ablation (LA), combustion (C), gas chromatography (GC) and isotope ratio mass spectrometry (IRMS) (LA-C-GC-IRMS). Sample material was extracted every 6 min with a UV-laser from a tree core, leaving 40-microm-wide holes. Ablated wood dust was combusted to CO2 at 700 degrees C, separated from other gases on a GC column and injected into an isotope ratio mass spectrometer after removal of water vapor. The measurements were calibrated against an internal and an external standard. The tree core remained intact and could be used for subsequent dendrochronological and dendrochemical analyses. Cores from two Scots pine trees (Pinus sylvestris spp. sibirica Lebed.) from central Siberia were sampled. Inter- and intra-annual patterns of delta13C in whole-wood and lignin-extracted cores were indistinguishable apart from a constant offset, suggesting that lignin extraction is unnecessary for our method. Comparison with the conventional method (microtome slicing, elemental analysis and IRMS) indicated high accuracy of the LA-C-GC-IRMS measurements. Patterns of delta13C along three parallel ablation lines on the same core showed high congruence. A conservative estimate of the precision was +/- 0.24 per thousand. Isotopic patterns of the two Scots pine trees were broadly similar, indicating a signal related to the forest stand's climate history. The maximum variation in delta13C over 22 years was about 5 per thousand, ranging from -27 to -22.3 per thousand. The most obvious pattern was a sharp decline in delta13C during latewood formation and a rapid increase with spring early growth. We conclude that the LA-C-GC-IRMS method will be useful in elucidating short-term climate effects on the delta13C signal in tree rings.

Development and validation of an universal interface for compound-specific stable isotope analysis of chlorine (37Cl/35Cl) by GC-high-temperature conversion (HTC)-MS/IRMS.

Science.gov (United States)

Renpenning, Julian; Hitzfeld, Kristina L; Gilevska, Tetyana; Nijenhuis, Ivonne; Gehre, Matthias; Richnow, Hans-Hermann

2015-03-03

A universal application of compound-specific isotope analysis of chlorine was thus far limited by the availability of suitable analysis techniques. In this study, gas chromatography in combination with a high-temperature conversion interface (GC-HTC), converting organic chlorine in the presence of H2 to gaseous HCl, was coupled to a dual-detection system, combining an ion trap mass spectrometer (MS) and isotope-ratio mass spectrometer (IRMS). The combination of the MS/IRMS detection enabled a detailed characterization, optimization, and online monitoring of the high-temperature conversion process via ion trap MS as well as a simultaneous chlorine isotope analysis by the IRMS. Using GC-HTC-MS/IRMS, chlorine isotope analysis at optimized conversion conditions resulted in very accurate isotope values (δ(37)Cl(SMOC)) for measured reference material with known isotope composition, including chlorinated ethylene, chloromethane, hexachlorocyclohexane, and trichloroacetic acids methyl ester. Respective detection limits were determined to be <15 nmol Cl on column with achieved precision of <0.3‰.

Interação entre irmãos de indivíduos com deficiência mental: o papel da idade e do apoio social da família.

OpenAIRE

Célia Cristina Nunes

2006-01-01

A presença de uma criança com necessidades especiais na família afeta não somente os pais, como também os outros membros dessa família e, muito especialmente, os irmãos. Estes membros podem se envolver direta ou indiretamente nos cuidados do irmão com necessidades especiais, sendo essa uma população de risco para apresentar problemas de ajustamento psicológico e de comportamento, mas ainda pouco pesquisada, sobretudo no Brasil. A forma como os irmãos respondem à presença de um indivíduo...

Detection of Synthetic Testosterone Use by Novel Comprehensive Two-Dimensional Gas Chromatography Combustion Isotope Ratio Mass Spectrometry (GC×GCC-IRMS)

Science.gov (United States)

Tobias, Herbert J.; Zhang, Ying; Auchus, Richard J.; Brenna, J. Thomas

2011-01-01

We report the first demonstration of Comprehensive Two-dimensional Gas Chromatography Combustion Isotope Ratio Mass Spectrometry (GC×GCC-IRMS) for the analysis of urinary steroids to detect illicit synthetic testosterone use, of interest in sport doping. GC coupled to IRMS (GCC-IRMS) is currently used to measure the carbon isotope ratios (CIR, δ13C) of urinary steroids in anti-doping efforts; however, extensive cleanup of urine extracts is required prior to analysis to enable baseline separation of target steroids. With its greater separation capabilities, GC×GC has the potential to reduce sample preparation requirements and enable CIR analysis of minimally processed urine extracts. Challenges addressed include on-line reactors with minimized dimensions to retain narrow peaks shapes, baseline separation of peaks in some cases, and reconstruction of isotopic information from sliced steroid chromatographic peaks. Difficulties remaining include long-term robustness of on-line reactors and urine matrix effects that preclude baseline separation and isotopic analysis of low concentration and trace components. In this work, steroids were extracted, acetylated, and analyzed using a refined, home-built GC×GCC-IRMS system. 11-hydroxy-androsterone (11OHA) and 11-ketoetiocolanolone (11KE) were chosen as endogenous reference compounds (ERC) because of their satisfactory signal intensity, and their CIR was compared to target compounds (TC) androsterone (A) and etiocholanolone (E). Separately, a GC×GC-qMS system was used to measure testosterone (T)/EpiT concentration ratios. Urinary extracts of urine pooled from professional athletes, and urine from one individual that received testosterone gel (T-gel) and one individual that received testosterone injections (T-shot) were analyzed. The average precisions of δ13C and Δδ13C measurements were SD(δ13C) approximately ± 1‰ (n=11). The T-shot sample resulted in a positive for T use with a T/EpiT ratio of > 9 and CIR

Penggantian Slave Arm Ms-manipulator Hotcell Uji 02 Dan 03 Irm

OpenAIRE

Gogo, Antonio; Basiran

2015-01-01

─ The replacement of the failure slave arm unit of MS-manipulator in hot cell 02 and 03 of Radiometallurgy Installations (IRM) has been done. This replacement purposes in order to refunctioned the failure MS-manipulator (5 units) in examination hot cell 02 and 03. The slave arm unit of MS-manipulator in examination hot cell 02 and 03 using a hanging device so it is impossible to pulled the slave arm units out to the operating area. The handling process cover; setting zero position on master a...

Comparison between IRMS and CRDS methods in the determination of isotopic ratios 2H/1H and 18O/16O in water

International Nuclear Information System (INIS)

Santos, T. H. R.; Zucchi, M. R.; Lemaire, T.; Azevedo, A. E. G.

2013-01-01

Traditionally, the method used for measuring the isotope ratios is the Isotope Ratio Mass Spectrometers (IRMS). A new method has been used to determine the isotopic abundances, the Cavity Ring-Down Spectroscopy (CRDS). It consists of a technique of direct absorption, of high sensitivity, which is based on measuring the absorption ratio, as a function of time, of the light confined in a high finesse optical cavity, instead of the magnitude of light beam absorption. The values of 18 O/ 16 O and D/H ratios are determined with respect to international standards VSMOW, GISP and SLAP from the International Atomic Energy Agency (IAEA). In this work, the IRMS and CRDS techniques are compared, verifying that the CRDS technique is promising and has some advantages compared to IRMS. It uses a smaller amount of sample, the isotope measurements are made simultaneously from the steam, reducing the analysis time. It also shows good reproducibility and accuracy, and it does not require a preliminary sample preparation.

Analysis of dissolved organic carbon concentration and 13C isotopic signature by TOC-IRMS - assessment of analytical performance

Science.gov (United States)

Kirkels, Frédérique; Cerli, Chiara; Federherr, Eugen; Kalbitz, Karsten

2013-04-01

Stable carbon isotopes provide a powerful tool to assess carbon pools and their dynamics. Dissolved organic carbon (DOC) has been recognized to play an important role in ecosystem functioning and carbon cycling and has therefore gained increased research interest. However, direct measurement of 13C isotopic signature of carbon in the dissolved phase is technically challenging particularly using high temperature combustion. Until recently, mainly custom-made systems existed which were modified for coupling of TOC instruments with IRMS for simultaneous assessment of C content and isotopic signature. The variety of coupled systems showed differences in their analytical performances. For analysis of DOC high temperature combustion is recognized as best performing method, owing to its high efficiency of conversion to CO2 also for highly refractory components (e.g. humic, fulvic acids) present in DOC and soil extracts. Therefore, we tested high temperature combustion TOC coupled to IRMS (developed by Elementar Group) for bulk measurements of DOC concentration and 13C signature. The instruments are coupled via an Interface to exchange the carrier gas from O2 to He and to concentrate the derived CO2 for the isotope measurement. Analytical performance of the system was assessed for a variety of organic compounds characterized by different stability and complexity, including humic acid and DOM. We tested injection volumes between 0.2-3 ml, thereby enabling measurement of broad concentration ranges. With an injection volume of 0.5 ml (n=3, preceded by 1 discarded injection), DOC and 13C signatures for concentrations between 5-150 mg C/L were analyzed with high precision (standard deviation (SD) predominantly TOC-IRMS in comparison with other systems capable of determining C concentration and isotopic signatures. We recognize the advantages of this system providing: - High sample throughput, short measurement time (15 minutes), flexible sample volume - Easy maintenance

pH-dependent equilibrium isotope fractionation associated with the compound specific nitrogen and carbon isotope analysis of substituted anilines by SPME-GC/IRMS.

Science.gov (United States)

Skarpeli-Liati, Marita; Turgeon, Aurora; Garr, Ashley N; Arnold, William A; Cramer, Christopher J; Hofstetter, Thomas B

2011-03-01

Solid-phase microextraction (SPME) coupled to gas chromatography/isotope ratio mass spectrometry (GC/IRMS) was used to elucidate the effects of N-atom protonation on the analysis of N and C isotope signatures of selected aromatic amines. Precise and accurate isotope ratios were measured using polydimethylsiloxane/divinylbenzene (PDMS/DVB) as the SPME fiber material at solution pH-values that exceeded the pK(a) of the substituted aniline's conjugate acid by two pH-units. Deviations of δ(15)N and δ(13)C-values from reference measurements by elemental analyzer IRMS were small (IRMS. Under these conditions, the detection limits for accurate isotope ratio measurements were between 0.64 and 2.1 mg L(-1) for δ(15)N and between 0.13 and 0.54 mg L(-1) for δ(13)C, respectively. Substantial inverse N isotope fractionation was observed by SPME-GC/IRMS as the fraction of protonated species increased with decreasing pH leading to deviations of -20‰ while the corresponding δ(13)C-values were largely invariant. From isotope ratio analysis at different solution pHs and theoretical calculations by density functional theory, we derived equilibrium isotope effects, EIEs, pertinent to aromatic amine protonation of 0.980 and 1.001 for N and C, respectively, which were very similar for all compounds investigated. Our work shows that N-atom protonation can compromise accurate compound-specific N isotope analysis of aromatic amines.

Metrology for stable isotope reference materials: 13C/12C and 18O/16O isotope ratio value assignment of pure carbon dioxide gas samples on the Vienna PeeDee Belemnite-CO2 scale using dual-inlet mass spectrometry.

Science.gov (United States)

Srivastava, Abneesh; Michael Verkouteren, R

2018-05-25

Isotope ratio measurements have been conducted on a series of isotopically distinct pure CO 2 gas samples using the technique of dual-inlet isotope ratio mass spectrometry (DI-IRMS). The influence of instrumental parameters, data normalization schemes on the metrological traceability and uncertainty of the sample isotope composition have been characterized. Traceability to the Vienna PeeDee Belemnite(VPDB)-CO 2 scale was realized using the pure CO 2 isotope reference materials(IRMs) 8562, 8563, and 8564. The uncertainty analyses include contributions associated with the values of iRMs and the repeatability and reproducibility of our measurements. Our DI-IRMS measurement system is demonstrated to have high long-term stability, approaching a precision of 0.001 parts-per-thousand for the 45/44 and 46/44 ion signal ratios. The single- and two-point normalization bias for the iRMs were found to be within their published standard uncertainty values. The values of 13 C/ 12 C and 18 O/ 16 O isotope ratios are expressed relative to VPDB-CO 2 using the [Formula: see text] and [Formula: see text] notation, respectively, in parts-per-thousand (‰ or per mil). For the samples, value assignments between (-25 to +2) ‰ and (-33 to -1) ‰ with nominal combined standard uncertainties of (0.05, 0.3) ‰ for [Formula: see text] and [Formula: see text], respectively were obtained. These samples are used as laboratory reference to provide anchor points for value assignment of isotope ratios (with VPDB traceability) to pure CO 2 samples. Additionally, they serve as potential parent isotopic source material required for the development of gravimetric based iRMs of CO 2 in CO 2 -free dry air in high pressure gas cylinder packages at desired abundance levels and isotopic composition values. Graphical abstract CO 2 gas isotope ratio metrology.

Potential of IRMS technology for tracing gamma-butyrolactone (GBL).

Science.gov (United States)

Marclay, François; Pazos, Diego; Delémont, Olivier; Esseiva, Pierre; Saudan, Christophe

2010-05-20

Popularity of gamma-hydroxybutyric acid (GHB) is fairly stable among drug users, while the consumption of its chemical precursor, gamma-butyrolactone (GBL), is a growing phenomenon. Although conventional analytical methods allow to detect this substance in various matrices, linking a trace and a source is still a difficult challenge. However, as several synthesis pathways and chemical precursors exist for the production of GBL, its carbon isotopic signature may vary extensively. For that purpose, a method has been developed to determine the carbon isotopes content of GBL by means of gas chromatography/combustion/isotope ratio mass spectrometry (GC/C/IRMS). The delta(13)C-values of 19 bulk samples purchased worldwide were in the range from -23.1 to -45.8 per thousand (SDIRMS for discriminating between seizures of GBL and for source determination.

Hyphomycetes isolados da água e do solo da Reserva Florestal de Dois Irmãos, Recife, PE, Brasil Hyphomycetes from water and soil at the Dois Irmãos Forest Reserve, Recife, Pernambuco State, Brazil

Directory of Open Access Journals (Sweden)

Marilene da Silva Cavalcanti

2007-12-01

Full Text Available (Hyphomycetes isolados da água e do solo, da Reserva Florestal de Dois Irmãos, Recife, PE, Brasil. Visando ampliar o conhecimento sobre a diversidade de fungos em ambientes aquáticos, coletas da água e do solo das margens dos açudes do Vale do Prata e do Meio foram efetuadas na Reserva Florestal de Dois Irmãos, Recife, Estado de Pernambuco. Dentre outras, foram isoladas cinco espécies pouco comuns de Hyphomycetes. As amostras de água foram coletadas abaixo da lâmina d'água e as de solo nas margens dos referidos açudes. As amostras de solo foram submetidas a diluições até 1:10000 e 1 mL de cada suspensão foi plaqueado no meio de Martin acrescido de cloranfenicol (50 mg/L. Alíquotas (1 mL das amostras de água foram semeadas no mesmo meio. As placas foram deixadas em temperatura ambiente (27 ºC±2, durante 3-4 dias, para o desenvolvimento de colônias e posterior isolamento dos fungos. Dentre as espécies identificadas Curvularia tuberculata Jain, Dendrosporium lobatum Plakidas & Edgerton ex Crane, Dichotomophthoropsis nymphaearum (Rand M. B. Ellis, Phaeoisaria glauca (Ellis & Everh. Hoog & Papendorf e Trichurus spiralis Hasselbring são destacadas porque haviam sido pouco referidas e não descritas anteriormente no Brasil.(Hyphomycetes from water and soil at the Dois Irmãos Forest Reserve, Recife, Pernambuco State, Brazil. To increase our knowledge regarding fungal diversity in aquatic environments, water and soil were collected at the edge of two dams (Açude do Vale do Prata and Açude do Meio at the Dois Irmãos Forest Reserve, Recife, Pernambuco state. Five uncommon species of Hyphomycetes were found, among others. Water samples were collected below the water surface and soil samples from the shores of these dams. Soil samples were diluted to 1:10000, and 1 mL of each suspension was plated in Martin's medium with 50 mg/L chloranphenicol. Water samples (1 mL were plated in the same medium. The plates were left at room

Differentiation of partial acylglycerols derived from different animal fats by EA-IRMS and GCMS techniques

Energy Technology Data Exchange (ETDEWEB)

Nina Naquiah, A.N.; Marikkar, J.M.N.; Shuhaimi, M.

2016-07-01

A study was carried out to compare partial acylglycerols of lard with those of chicken fat, beef fat and mutton fat using Gas Chromatography Mass Spectrometry (GC-MS) and Elemental Analysis–Isotope Ratio Mass Spectrometry (EA-IRMS). Mono- (MAG) and di-(DAG) acylglycerols of animal fats were prepared according to a chemical glycerolysis method and isolated using column chromatography. The fatty acid composition and δ13C carbon isotope ratio of MAG and DAG derived from individual animal fat were determined separately to establish their identity characteristics. The results showed that the δ13C values of MAG and DAG of lard were significantly different from those of MAG and DAG derived from chicken fat, beef fat and mutton fat. According to the loading plots based on a principle component analysis (PCA), fatty acids namely stearic, oleic and linoleic were the most discriminating parameters to distinctly identify MAG and DAG derived from different animal fats. This demonstrated that the EA-IRMS and the PCA of fatty acid data have considerable potential for discriminating MAG and DAG derived from lard from other animal fats for Halal authentication purposes. (Author)

Analysis of 13C-mixed triacylglycerol in stool by bulk (EA-IRMS) and compound specific (GC/MS) methods.

Science.gov (United States)

Slater, C; Ling, S C; Preston, T; Weaver, L T

2002-06-01

This paper was presented in poster form at the 17th International Congress of Nutrition, August 27-31, Vienna, Austria (Annals of Nutrition & Metabolism 2001; 45(Suppl.1):349). Some of the data were also presented in poster form at the British Society of Gastroenterology Meeting, March 18-21, Glasgow, UK (Gut 2001; 48(Suppl.1):A91). The 13C-mixed triacylglycerol (MTG) breath test is used to measure intraluminal fat digestion. In normal digestion, 20-40% of the ingested 13C label is recovered in breath CO2. We aimed to identify the proportions of ingested label excreted in stool, as well as breath following ingestion of 13C-MTG by children with impaired exocrine pancreatic function and healthy controls. 13C enrichment of breath samples was measured by continuous flow isotope ratio mass spectrometry (IRMS) and cumulative percent dose recovered (cPDR) in 10 h was calculated. Total 13C of a faecal fat extract from each stool was measured by elemental analyser-IRMS, and 13C enrichment and concentration of the TBDMS derivative of octanoic acid was measured by GC/MS after hydrolysis of the fat extract. Stool 5-day cPDR was calculated. Mean breath cPDR was 35%. Mean cPDR in stool by combustion-IRMS and GC/ MS, respectively, was 0.8% and 1.0%. Therefore, the remaining 64% of the 13C label must remain in the body and variability in breath cPDR is due to postabsorptive rather than predigestive factors.

USE OF GC-MS/COMBUSTION/IRMS TO IDENTIFY AND DETERMINE THE STABLE CARBON ISOTOPIC RATIO OF INDIVIDUAL LIPIDS

Science.gov (United States)

A system that couples a gas chromatograph (GC) via a split to a quadrapole mass spectrometer (MS) and, through a combustion interface, to an isotope ratio mass spectrometer (IRMS) allows the simultaneous detection of electron impact mass spectra and stable carbon isotope ratio an...

U. S. Department of Education Information Resources Management (IRM) Strategic Plan, FY2010-2014. Version 1.5

Science.gov (United States)

US Department of Education, 2010

2010-01-01

The Chief Information Officer (CIO) at the U.S. Department of Education (the Department) has primary responsibility to ensure that Information Technology (IT) is acquired and information resources are managed in a manner consistent with statutory, regulatory, and Departmental requirements and priorities. This Department Information Resources…

Differentiation of partial acylglycerols derived from different animal fats by EA-IRMS and GCMS techniques

Directory of Open Access Journals (Sweden)

Nina Naquiah, A. N.

2016-06-01

Full Text Available A study was carried out to compare partial acylglycerols of lard with those of chicken fat, beef fat and mutton fat using Gas Chromatography Mass Spectrometry (GC-MS and Elemental Analysis–Isotope Ratio Mass Spectrometry (EA-IRMS. Mono- (MAG and di-(DAG acylglycerols of animal fats were prepared according to a chemical glycerolysis method and isolated using column chromatography. The fatty acid composition and δ13C carbon isotope ratio of MAG and DAG derived from individual animal fat were determined separately to establish their identity characteristics. The results showed that the δ13C values of MAG and DAG of lard were significantly different from those of MAG and DAG derived from chicken fat, beef fat and mutton fat. According to the loading plots based on a principle component analysis (PCA, fatty acids namely stearic, oleic and linoleic were the most discriminating parameters to distinctly identify MAG and DAG derived from different animal fats. This demonstrated that the EA-IRMS and the PCA of fatty acid data have considerable potential for discriminating MAG and DAG derived from lard from other animal fats for Halal authentication purposes.Se realizó un estudio para comparar acilgliceroles parciales de la manteca de cerdo con las de grasa de pollo, grasa de vacuno y grasa de cordero utilizando cromatografía de gases-espectrometría de masas (GC-MS y análisis elemental de Isótopos-Espectrometría de Masas (EA-IRMS. Los mono- (MAG y di- (DAG acilgliceroles de grasas animales se prepararon mediante un método de glicerolisis química y se aislaron mediante cromatografía en columna. La composición de ácidos grasos y la relación isotópica de carbono δ13C de los MAG y DAG de las grasas de animales se determinan por separado para establecer sus características de identidad. Los resultados mostraron que los valores de δ13C de MAG y DAG de la manteca de cerdo fue significativamente diferente de los de MAG y DAG derivados de grasa

Uma genealogia do deslocamento em Dois Irmãos de Miltom Hatoum

OpenAIRE

Mackellene, Léo

2011-01-01

A escrita de Milton Hatoum é constituída de deslocamentos: não só os personagens o são, mas também a própria estrutura de sua narrativa. Este artigo pretende demonstrar, a partir da análise de Dois Irmãos, que, falando do deslocamento dos personagens, o autor fala de seu próprio deslocamento, do deslocamento do homem contemporâneo, em sua dimensão pós-moderna e pós-colonial, e, ainda, do deslocamento do próprio leitor de suas obras.

Challenges of 13C/12C measurements by CF-IRMS of biochemical samples at sub-nanomolar levels

International Nuclear Information System (INIS)

Whiticar, M.J.; Eek, M.

2001-01-01

Recent refinements to instrumentation and methodology have facilitated measurement of 13 C/ 12 C of individual compounds within complex biogeochemical mixtures by CF-IRMS. Specific challenges such as instrument performance, effective compound partitioning, efficient combustion, effective water removal, and isotope effects during online preparation of gases are discussed and practical improvements are presented. (author)

(13)C/(12)C isotope ratios of organic acids, glucose and fructose determined by HPLC-co-IRMS for lemon juices authenticity.

Science.gov (United States)

Guyon, Francois; Auberger, Pauline; Gaillard, Laetita; Loublanches, Caroline; Viateau, Maryse; Sabathié, Nathalie; Salagoïty, Marie-Hélène; Médina, Bernard

2014-03-01

High performance liquid chromatography linked to isotope ratio mass spectrometry via an interface allowing the chemical oxidation of organic matter (HPLC-co-IRMS) was used to simultaneously determine carbon 13 isotope ratio (δ(13)C) of organic acids, glucose and fructose in lime and lemon juices. Because of the significant difference between organic acids and sugars concentrations, the experimental protocol was optimised by applying a "current jump" to the IRMS device. The filament current is increased of 300μA during elution in order to enhance IRMS sensitivity. Then, analysis were performed on 35 lemon and lime fruits from various geographical origins and squeezed in the laboratory. An overall average δ(13)C values of -25.40±1.62‰, -23.83±1.82‰ and -25.67±1.72‰ is found for organic acids mixture mainly made up of citric acid, glucose and fructose, respectively. These authentic samples allowed the definition of a confidence domain to which have been confronted 30 commercial juices (24 "pure juices" and 6 coming from concentrate). Among these 30 samples, 10 present δ(13)C values outside the defined range revealing an added "C4" type organic acids or sugars, addition not specified on the label that is not in agreement with EU regulation. Copyright © 2013 Elsevier Ltd. All rights reserved.

see Gupta VK 433 Andreev V see Porcellato AM 963 Antony J see ...

Indian Academy of Sciences (India)

Cryogenic, superconducting and rf results of the SRFQ2 of PIAVE. 963. Prakash P N. Superconducting linear accelerator system for. NSC. 849 see Ghosh S. 881. Prakash S see Sharma Hitesh. 497. Prasad J see Chopra S. 753. Prasad Moonooku see Pande S A. 859. Prasad R L. CO2 laser photoacoustic spectra and vibra-.

Differentiation of lard, chicken fat, beef fat and mutton fat by GCMS and EA-IRMS techniques.

Science.gov (United States)

Ahmad Nizar, Nina Naquiah; Nazrim Marikkar, Jalaldeen Mohamed; Hashim, Dzulkifly Mat

2013-01-01

A study was conducted to differentiate lard, chicken fat, beef fat and mutton fat using Gas Chromatography Mass Spectrometry (GC-MS) and Elemental Analyzer-Isotope Ratio Mass Spectrometry (EA-IRMS). The comparison of overall fatty acid data showed that lard and chicken fat share common characteristics by having palmitic, oleic and linoleic acid as major fatty acids while beef and mutton fats shared common characteristics by possessing palmitic, stearic and oleic acid as major fatty acids. The direct comparisons among the fatty acid data, therefore, may not be suitable for discrimination of different animal fats. When the fatty acid distributional data was subjected to Principle Component Analysis (PCA), it was demonstrated that stearic, oleic and linoleic acids as the most discriminating parameters in the clustering of animal fats into four subclasses. The bulk carbon analysis of animal fats using EA-IRMS showed that determination of the carbon isotope ratios (δ¹³C) would be a good indicator for discriminating lard, chicken fat, beef fat and mutton fat. This would lead to a faster and more efficient method to ascertain the source of origin of fats used in food products.

Forensic analysis of explosives using isotope ratio mass spectrometry (IRMS)--discrimination of ammonium nitrate sources.

Science.gov (United States)

Benson, Sarah J; Lennard, Christopher J; Maynard, Philip; Hill, David M; Andrew, Anita S; Roux, Claude

2009-06-01

An evaluation was undertaken to determine if isotope ratio mass spectrometry (IRMS) could assist in the investigation of complex forensic cases by providing a level of discrimination not achievable utilising traditional forensic techniques. The focus of the research was on ammonium nitrate (AN), a common oxidiser used in improvised explosive mixtures. The potential value of IRMS to attribute Australian AN samples to the manufacturing source was demonstrated through the development of a preliminary AN classification scheme based on nitrogen isotopes. Although the discrimination utilising nitrogen isotopes alone was limited and only relevant to samples from the three Australian manufacturers during the evaluated time period, the classification scheme has potential as an investigative aid. Combining oxygen and hydrogen stable isotope values permitted the differentiation of AN prills from three different Australian manufacturers. Samples from five different overseas sources could be differentiated utilising a combination of the nitrogen, oxygen and hydrogen isotope values. Limited differentiation between Australian and overseas prills was achieved for the samples analysed. The comparison of nitrogen isotope values from intact AN prill samples with those from post-blast AN prill residues highlighted that the nitrogen isotopic composition of the prills was not maintained post-blast; hence, limiting the technique to analysis of un-reacted explosive material.

Simultaneous determination of wine sugars, glycerol and organic acids 13C/12C isotopic ratio by ion chromatography-co-IRMS

Directory of Open Access Journals (Sweden)

Guyon Francois

2014-01-01

Full Text Available Ion chromatography (IC isotope ratio mass spectrometry (IRMS coupling is possible using a liquid interface allowing chemical oxidation (co of organic compounds. Synthetic solutions containing a mixture of glycerol, sugars (sucrose, glucose and fructose and organic acids (gluconic, lactic, malic, tartaric, oxalic, fumaric, citric and isocitric were elaborated to estimate analytical applications of two different IC systems. It appears that the use of carbonated solution in the eluting phase is a perturbation for 13C isotope measurements as it creates a δ13C deviation from the expected values. A sample of authentic sweet wine was analyzed by IC-co-IRMS using KOH gradient. Ratios of isotopic, ratios of organic acids and glycerol was found to be, in average, equal 1.01 ± 0.04 that is in accordance with our previous results.

A 244Pu spike reference material CBNM IRM-042A

International Nuclear Information System (INIS)

Verbruggen, A.; Gallet, M.; Hendrickx, F.; Bievre, P. de

1991-01-01

An highly enriched 244 Pu isotopic reference material (CBNM IRM-042a) has been prepared and certified for 244 Pu isotope concentration. The certified value of (2.257 7 ± 0.004 4).10 18 atoms 242 Pu.kg -1 of solution has been established by isotope dilution mass spectrometry. The plutonium isotopic composition has been determined by thermal ionization mass spectrometry and calibration of these measurements by means of synthetic 242 Pu/ 239 Pu mixtures. The isotopic reference material is supplied in a sealed glass ampoule containing approximately 10 g of a 5M nitric acid solution at an approximate concentration of 1 μg Pu per g solution. This isotopic reference material is part of a systematic CBNM programme to supply spike isotopic reference materials of various isotopes at different concentrations

Ter um irmão especial: convivendo com a Síndrome de Down Having a special brother/sister: living together with the Down Syndrome

Directory of Open Access Journals (Sweden)

Eucia Beatriz Lopes Petean

2005-12-01

Full Text Available O presente estudo teve por objetivos conhecer como é a relação entre irmãos mais velhos de pessoas com diagnóstico de Síndrome de Down (SD; que informações e sentimentos possuem sobre o diagnóstico; se houve ou não modificações na dinâmica familiar e em suas próprias vidas. Foram entrevistadas 11 pessoas, de ambos os sexos, com idade superior a dez anos, sendo, cada uma, o irmão mais velho de criança com diagnóstico de SD, sendo realizada análise quantitativa de dados da amostra e análise quantitativa-interpretativa e qualitativa para os dados da entrevista. Os dados mostram que a maioria dos sujeitos (90,9% sabe o nome da Síndrome e foram informados pela mãe logo após o nascimento do irmão, seis deles consideram que reagiram normalmente à notícia. Quanto às responsabilidades adquiridas, a maioria, 90,9%, são responsáveis pelas atividades de vida diária; 27,27% deles consideram que houve acréscimo de responsabilidade em suas vidas em decorrência do nascimento do irmão com SD. Em relação ao sentimento que apresentam por terem um irmão especial, 54,54% consideram como positivo, ou seja, disseram que também sentem-se especiais. Na falta (morte dos pais, a metade dos participantes informa que eles serão os responsáveis legais deste irmão. Pode-se concluir que o nascimento de um irmão com SD tem conseqüências na rotina de vida dos irmãos mais velhos, trazendo modificações e responsabilidades para eles. Entretanto, parece ter um efeito menos dirigido para a desestrutura psicológica, sendo poucas as manifestações de sentimentos extremos, ficando apenas no nível da tristeza, quando são expressos.The present study intended to know about the relation among older brothers/sisters of people with a diagnosis of Down Syndrome (DS, regarding to information and feelings they have about this diagnosis, and if changes have occurred within family dynamics and their own lives. Eleven people were interviewed, from

A new combined nanoSIMS and continuous-flow IRMS approach to measure hydrogen isotopes from water in hydrated rhyolitic glass

Science.gov (United States)

Gatti, E.; Kitchen, N.; Newman, S.; Guan, Y.; Westgate, J.; Pearce, N. J. G.; Nikolic, D.; Eiler, J. M.

2016-12-01

The hydrogen-isotope value of water of hydration (or secondary water) preserved in rhyolitic glasses may provide significant insights regarding the climate at the time of their deposition and the impact of super-eruptions upon the environment. However, the ability of the glass to retain the environmental D/H isotopic signal after hydration needs to be tested, since modifications to the D/H systematics may result from the continuous exchange of D/H with the atmosphere or condensed water after initial glass hydration. Ideal geological archives to test whether the glass retains its original hydrogen signal are sediments in natural waters and ice cores, which preserve tephra in constrained horizons that can be independently isotopically characterised. However, tephra in marine and fresh water sediments and ice cores are often present in concentrations of the order of 1000 grains/cm3 (IRMS methods require much more material ( 100-500 mg) and therefore cannot be applied. We present here a new integrated nanoSIMS and continuous flow IRMS approach to understand how water is distributed within single glass grains (diffusion profiles), quantify the time of hydration of young (Holocene) and old (Miocene) already well-characterised rhyolitic glasses, and measure the D/H ratio of the hydration water on single grains and bulk material consisting of only approximately 0.1-1 mg. The IRMS method measures the absolute abundance of hydrogen released from the sample by continuous-flow mass spectrometry. Current data indicates that the method can accurately measure a hydrogen signal from a rock sample containing at least 400 nanomoles of H2, corresponding to 70 µg of water, which translates to 1 mg of hydrous glass (>3 wt%) or 15 mg of dry ( 0.5 wt%) obsidian chips. The method can be improved by reducing the blank to IRMS method will be compared to sub-micron mapping of single-grains using a high-resolution ion microprobe, the CAMECA NanoSIMS 50L, in the Microanalysis Center for

The measurement of muscle protein synthesis in broilers with a flooding dose technique: use of 15N-labelled phenylalanine, GC-MS and GC-C-IRMS.

Science.gov (United States)

Dänicke, S; Böttcher, W; Simon, O; Jeroch, H

2001-01-01

An experiment was carried out to measure fractional muscle protein synthesis rates (k(s)) in broilers with injection of a flooding dose of phenylalanine (1 ml/100 g body weight of 150 mM phenylalanine; 38 atom percent excess (APE) [15N]phenylalanine). K(s) was calculated from the [15N] enrichment in phenylalanine of tissue-free and protein-bound phenylalanine using both gas chromatography mass spectrometry (GC-MS) and gas chromatography combustion isotope ratio mass spectrometry (GC-C-IRMS) for measurements after a 10 min isotope incorporation period. The tertiary-butyldimethylsilyl (t-BDMS) derivatives of phenylalanine were used for gas chromatographic separation in both systems. GC-MS and GC-C-IRMS were calibrated for a range of 7 to 37 [15N]APE and 0 to 0.62 [15N]APE, respectively, and for sample sizes of 0.45 to 4.5 nmol phenylalanine and 7 to 40 nmol phenylalanine, respectively. Reproducibility of standards as a measure of precision varied from 0.06 to 0.29 [15N]APE and from 0.0004 to 0.0018 [15N]APE in GC-MS and GC-C-IRMS, respectively. K(s) was measured in the m. pectoralis major of broilers fed rye based diets (56%) which were provided either unsupplemented (-) or supplemented (+) with an enzyme preparation containing xylanase. K(s) in breast muscles was significantly increased from 21.8%/d to 23.9%/d due to enzyme supplementation. It can be concluded from the study that the measurement of protein synthesis in broilers with the flooding dose technique can be carried out by using [15N]phenylalanine, GC-MS and GC-C-IRMS.

Continuous flow IRMS application to CH4, MNHCS, and N2O in the atmosphere and the oceans

International Nuclear Information System (INIS)

Yoshida, N.; Tsunogai, U.; Toyoda, S.

2001-01-01

The application of CF-IRMS to measurement of methane (CH4), non-methane hydrocarbons (NMHCS), and nitrous oxide (N 2 O) is outlined and preliminary information on isotopic variations in the atmosphere and oceans is presented. Labelling of these compounds is expected to provide a robust method for tracing sources, sinks and controlling processes in the environment. (author)

Hanford high level waste: Sample Exchange/Evaluation (SEE) Program

International Nuclear Information System (INIS)

King, A.G.

1994-08-01

The Pacific Northwest Laboratory (PNL)/Analytical Chemistry Laboratory (ACL) and the Westinghouse Hanford Company (WHC)/Process Analytical Laboratory (PAL) provide analytical support services to various environmental restoration and waste management projects/programs at Hanford. In response to a US Department of Energy -- Richland Field Office (DOE-RL) audit, which questioned the comparability of analytical methods employed at each laboratory, the Sample Exchange/Exchange (SEE) program was initiated. The SEE Program is a selfassessment program designed to compare analytical methods of the PAL and ACL laboratories using sitespecific waste material. The SEE program is managed by a collaborative, the Quality Assurance Triad (Triad). Triad membership is made up of representatives from the WHC/PAL, PNL/ACL, and WHC Hanford Analytical Services Management (HASM) organizations. The Triad works together to design/evaluate/implement each phase of the SEE Program

Production of [Formula: see text] and [Formula: see text] in p-Pb collisions at [Formula: see text] TeV.

Science.gov (United States)

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Vinogradov, A; Vinogradov, L; Virgili, T; Vislavicius, V; Vodopyanov, A; Völkl, M A; Voloshin, K; Voloshin, S A; Volpe, G; von Haller, B; Vorobyev, I; Voscek, D; Vranic, D; Vrláková, J; Wagner, B; Wagner, J; Wang, H; Wang, M; Watanabe, D; Watanabe, Y; Weber, M; Weber, S G; Weiser, D F; Wessels, J P; Westerhoff, U; Whitehead, A M; Wiechula, J; Wikne, J; Wilk, G; Wilkinson, J; Willems, G A; Williams, M C S; Windelband, B; Witt, W E; Yalcin, S; Yang, P; Yano, S; Yin, Z; Yokoyama, H; Yoo, I-K; Yoon, J H; Yurchenko, V; Zaccolo, V; Zaman, A; Zampolli, C; Zanoli, H J C; Zaporozhets, S; Zardoshti, N; Zarochentsev, A; Závada, P; Zaviyalov, N; Zbroszczyk, H; Zhalov, M; Zhang, H; Zhang, X; Zhang, Y; Zhang, C; Zhang, Z; Zhao, C; Zhigareva, N; Zhou, D; Zhou, Y; Zhou, Z; Zhu, H; Zhu, J; Zhu, X; Zichichi, A; Zimmermann, A; Zimmermann, M B; Zimmermann, S; Zinovjev, G; Zmeskal, J

2017-01-01

The transverse momentum distributions of the strange and double-strange hyperon resonances ([Formula: see text], [Formula: see text]) produced in p-Pb collisions at [Formula: see text] TeV were measured in the rapidity range [Formula: see text] for event classes corresponding to different charged-particle multiplicity densities, [Formula: see text]d[Formula: see text]/d[Formula: see text]. The mean transverse momentum values are presented as a function of [Formula: see text]d[Formula: see text]/d[Formula: see text], as well as a function of the particle masses and compared with previous results on hyperon production. The integrated yield ratios of excited to ground-state hyperons are constant as a function of [Formula: see text]d[Formula: see text]/d[Formula: see text]. The equivalent ratios to pions exhibit an increase with [Formula: see text]d[Formula: see text]/d[Formula: see text], depending on their strangeness content.

Paleodiet characterisation of an Etrurian population of Pontecagnano (Italy) by Isotope Ratio Mass Spectrometry (IRMS) and Atomic Absorption Spectrometry (AAS)(#).

Science.gov (United States)

Scarabino, Carla; Lubritto, Carmine; Proto, Antonio; Rubino, Mauro; Fiengo, Gilda; Marzaioli, Fabio; Passariello, Isabella; Busiello, Gaetano; Fortunato, Antonietta; Alfano, Davide; Sabbarese, Carlo; Rogalla, Detlef; De Cesare, Nicola; d'Onofrio, Antonio; Terrasi, Filippo

2006-06-01

Human bones recovered from the archaeological site of Pontecagnano (Salerno, Italy) have been studied to reconstruct the diet of an Etrurian population. Two different areas were investigated, named Library and Sant' Antonio, with a total of 44 tombs containing human skeletal remains, ranging in age from the 8th to the 3rd century B.C. This time span was confirmed by 14C dating obtained using Accelerator Mass Spectrometry (AMS) on one bone sample from each site. Atomic Absorption Spectrometry (AAS) was used to extract information about the concentration of Sr, Zn, Ca elements in the bone inorganic fraction, whilst stable isotope ratio measurements (IRMS) were carried out on bone collagen to obtain the delta13C and delta15N. A reliable technique has been used to extract and separate the inorganic and organic fractions of the bone remains. Both IRMS and AAS results suggest a mixed diet including C3 plant food and herbivore animals, consistent with archaeological indications.

Atypical excretion profile and GC/C/IRMS findings may last for nine months after a single dose of nandrolone decanoate.

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Palonek, Elzbieta; Ericsson, Magnus; Gårevik, Nina; Rane, Anders; Lehtihet, Mikael; Ekström, Lena

2016-04-01

The use of the anabolic androgenic steroid nandrolone and its prohormones is prohibited in sport. A common route of nandrolone administration is intramuscular injections of a nandrolone ester. Here we have investigated the detection time of nandrolone and 19-norandrosterone and 19-noretiocholanolone metabolites in eleven healthy men after the administration of a 150 mg dose of nandrolone decanoate. The urinary concentrations of nandrolone and the metabolites were monitored by GC-MS/MS for nine months and in some samples the presence of 19-norandrosterone was confirmed by GC/C/IRMS analysis. The participants were genotyped for polymorphisms in PDE7B1 and UGT2B15 genes previously shown to influence the activation and inactivation of nandrolone decanoate. There were large inter-individual variations in the excretion rate of nandrolone and the metabolites, although not related to genetic variations in the UGT2B15 (rs1902023) and PDE7B1 (rs7774640) genes. After the administration, 19-norandrosterone was found at 2-8-fold higher concentrations than 19-noretiocholanolone. We showed that nandrolone doping can be identified 4 and 9 months after the injection of only one single dose in six and three individuals, respectively. We also noted that GC/C/IRMS confirms the presence of exogenous 19-norandrosterone in the urine samples, showing δ13 values around -32 ‰. This was true even in a sample that was not identified as an atypical finding after the GC-MS/MS analysis further showing the power of using GC/C/IRMS in routine anti-doping settings. Copyright © 2016 Elsevier Inc. All rights reserved.

Development and validation of a GC-C-IRMS method for the confirmation analysis of pseudo-endogenous glucocorticoids in doping control.

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de la Torre, Xavier; Curcio, Davide; Colamonici, Cristiana; Molaioni, Francesco; Cilia, Marta; Botrè, Francesco

2015-01-01

Glucocorticoids are included in the S9 section of the World Anti-doping Agency (WADA) prohibited list international standard. Some among them are pseudo-endogenous steroids, like cortisol and cortisone, which present the same chemical structure as endogenously produced steroids. We are proposing an analytical method based on gas chromatography coupled to isotope ratio mass spectrometry (GC-C-IRMS) which allows discrimination between endogenous and synthetic origin of the urinary metabolites of the pseudo-endogenous glucocorticoids. A preliminary purification treatment by high-performance liquid chromatography (HPLC) of the target compounds (TC) (i.e., cortisol, tetrahydrocortisone (THE) 5α-tetrahydrocortisone (aTHE), tetrahydrocortisol (THF), and 5α-tetrahydrocortisol (aTHF)) allows collection of extracts with adequate purity for the subsequent analysis by IRMS. A population of 40 urine samples was analyzed for the TC and for the endogenous reference compounds (ERC: i.e., 11-desoxy-tetrahydrocortisol (THS) or pregnanediol). For each sample, the difference between the delta values of the ERCs and TCs (Δδ values) were calculated and based on that, some decision limits for atypical findings are proposed. The limits are below 3% units except for cortisol. The fit to purpose of the method has been confirmed by the analysis of urine samples collected in two patients under treatment with 25 mg of cortisone acetate (p.o). The samples showed Δδ values higher than 3 for at least 24 h following administration depending on the TC considered. The method can easily be integrated into existing procedures already used for the HPLC purification and IRMS analysis of pseudo-endogenous steroids with androgenic/anabolic activity. Copyright © 2015 John Wiley & Sons, Ltd.

Carbon Isotope Characterization of Organic Intermediaries in Hydrothermal Hydrocarbon Synthesis by Pyrolysis-GC-MS-C-IRMS

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Socki, Richard A.; Fu, Qi; Niles, Paul B.

2010-01-01

We report results of experiments designed to characterize the carbon isotope composition of intermediate organic compounds produced as a result of mineral surface catalyzed reactions. The impetus for this work stems from recently reported detection of methane in the Martian atmosphere coupled with evidence showing extensive water-rock interaction during Martian history. Abiotic formation by Fischer-Tropsch-type (FTT) synthesis during serpentinization reactions may be one possible process responsible for methane generation on Mars, and measurement of carbon and hydrogen isotopes of intermediary organic compounds can help constrain the origin of this methane. Of particular interest within the context of this work is the isotopic composition of organic intermediaries produced on the surfaces of mineral catalysts (i.e. magnetite) during hydrothermal experiments, and the ability to make meaningful and reproducible isotope measurements. Our isotope measurements utilize a unique analytical technique combining Pyrolysis-Gas Chromatograph-Mass Spectrometry-Combustion-Isotope Ratio Mass Specrometry (Py-GC-MS-C-IRMS). Others have conducted similar pyrolysis-IRMS experiments on low molecular weight organic acids (Dias, et al, Organic Geochemistry, 33 [2002]). Our technique differs in that it carries a split of the pyrolyzed GC-separated product to a Thermo DSQ-II quadrupole mass spectrometer as a means of making qualitative and semi-quantitative compositional measurements of the organic compounds. A sample of carboxylic acid (mixture of C1 through C6) was pyrolyzed at 100 XC and passed through the GC-MS-C-IRMS (combusted at 940 XC). In order to test the reliability of our technique we compared the _13C composition of different molecular weight organic acids (from C1 through C6) extracted individually by the traditional sealed-tube cupric oxide combustion (940 XC) method with the _13C produced by our pyrolysis technique. Our data indicate that an average 4.3. +/-0.5. (V

Production of K[Formula: see text](892)[Formula: see text] and [Formula: see text](1020) in p-Pb collisions at [Formula: see text] = 5.02 TeV.

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The production of K[Formula: see text](892)[Formula: see text] and [Formula: see text](1020) mesons has been measured in p-Pb collisions at [Formula: see text][Formula: see text] 5.02 TeV. K[Formula: see text] and [Formula: see text] are reconstructed via their decay into charged hadrons with the ALICE detector in the rapidity range [Formula: see text]. The transverse momentum spectra, measured as a function of the multiplicity, have a p[Formula: see text] range from 0 to 15 GeV/ c for K[Formula: see text] and from 0.3 to 21 GeV/ c for [Formula: see text]. Integrated yields, mean transverse momenta and particle ratios are reported and compared with results in pp collisions at [Formula: see text][Formula: see text] 7 TeV and Pb-Pb collisions at [Formula: see text][Formula: see text] 2.76 TeV. In Pb-Pb and p-Pb collisions, K[Formula: see text] and [Formula: see text] probe the hadronic phase of the system and contribute to the study of particle formation mechanisms by comparison with other identified hadrons. For this purpose, the mean transverse momenta and the differential proton-to-[Formula: see text] ratio are discussed as a function of the multiplicity of the event. The short-lived K[Formula: see text] is measured to investigate re-scattering effects, believed to be related to the size of the system and to the lifetime of the hadronic phase.

Inter-laboratory comparison of elemental analysis and gas chromatography combustion isotope ratio mass spectrometry (GC-C-IRMS). Part I: delta13C measurements of selected compounds for the development of an isotopic Grob-test.

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Serra, F; Janeiro, A; Calderone, G; Rojas, J M Moreno; Rhodes, C; Gonthier, L A; Martin, F; Lees, M; Mosandl, A; Sewenig, S; Hener, U; Henriques, B; Ramalho, L; Reniero, F; Teixeira, A J; Guillou, C

2007-03-01

This study was directed towards investigating suitable compounds to be used as stable isotope reference materials for gas chromatography combustion isotope ratio mass spectrometry (GC-C-IRMS) calibration. Several compounds were selected from those used in the 'Grob-test' mixture. Oxygen- and nitrogen-containing substances were added to these compounds to allow the mixture to be used as a possible multi-isotopic calibration tool for 2H/1H, 13C/12C, 15N/14N and 18O/16O ratio determinations. In this paper we present the results of delta13C measurements performed by the consortium of the five laboratories taking part in this inter-calibration exercise. All the compounds were individually assessed for homogeneity, short-term stability and long-term stability by means of EA-IRMS, as required by the bureau communitaire de reference (BCR) Guide for Production of Certified Reference Materials. The results were compared then with the GC-C-IRMS measurements using both polar and non-polar columns, and the final mixture of selected compounds underwent a further certification exercise assessing limits of accuracy and reproducibility under specified GC-C-IRMS conditions. Copyright 2007 John Wiley & Sons, Ltd.

Measurement of [Formula: see text] polarisation in [Formula: see text] collisions at [Formula: see text] = 7 TeV.

Science.gov (United States)

Aaij, R; Adeva, B; Adinolfi, M; Affolder, A; Ajaltouni, Z; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amerio, S; Amhis, Y; An, L; Anderlini, L; Anderson, J; Andreassen, R; Andreotti, M; Andrews, J E; Appleby, R B; Aquines Gutierrez, O; Archilli, F; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Bachmann, S; Back, J J; Badalov, A; Balagura, V; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Batozskaya, V; Bauer, Th; Bay, A; Beddow, J; Bedeschi, F; Bediaga, I; Belogurov, S; Belous, K; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Benton, J; Berezhnoy, A; Bernet, R; Bettler, M-O; van Beuzekom, M; Bien, A; Bifani, S; Bird, T; Bizzeti, A; Bjørnstad, P M; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Borsato, M; Bowcock, T J V; Bowen, E; Bozzi, C; Brambach, T; van den Brand, J; Bressieux, J; Brett, D; Britsch, M; Britton, T; Brook, N H; 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The polarisation of prompt [Formula: see text] mesons is measured by performing an angular analysis of [Formula: see text] decays using proton-proton collision data, corresponding to an integrated luminosity of 1.0[Formula: see text], collected by the LHCb detector at a centre-of-mass energy of 7 TeV. The polarisation is measured in bins of transverse momentum [Formula: see text] and rapidity [Formula: see text] in the kinematic region [Formula: see text] and [Formula: see text], and is compared to theoretical models. No significant polarisation is observed.

Observation of [Formula: see text] and [Formula: see text] decays.

Science.gov (United States)

Aaij, R; Adeva, B; Adinolfi, M; Ajaltouni, Z; Akar, S; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amerio, S; Amhis, Y; An, L; Anderlini, L; Andreassi, G; Andreotti, M; Andrews, J E; Appleby, R B; Archilli, F; d'Argent, P; Arnau Romeu, J; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Babuschkin, I; Bachmann, S; Back, J J; Badalov, A; Baesso, C; Baker, S; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Baszczyk, M; Batozskaya, V; Batsukh, B; Battista, V; Bay, A; Beaucourt, L; Beddow, J; Bedeschi, F; Bediaga, I; Bel, L J; Bellee, V; Belloli, N; Belous, K; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Benton, J; Berezhnoy, A; Bernet, R; Bertolin, A; Betancourt, C; Betti, F; Bettler, M-O; van Beuzekom, M; Bezshyiko, Ia; Bifani, S; Billoir, P; Bird, T; Birnkraut, A; Bitadze, A; Bizzeti, A; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Boettcher, T; Bondar, A; Bondar, N; Bonivento, W; Bordyuzhin, I; 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2017-01-01

The decays [Formula: see text] and [Formula: see text] are observed for the first time using a data sample corresponding to an integrated luminosity of 3.0 fb[Formula: see text], collected by the LHCb experiment in proton-proton collisions at the centre-of-mass energies of 7 and 8[Formula: see text]. The branching fractions relative to that of [Formula: see text] are measured to be [Formula: see text]where the first uncertainties are statistical and the second are systematic.

'You'll See That Everywhere': Institutional Isomorphism in Secondary School Subject Departments

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Puttick, Steven

2017-01-01

This paper asks why spatially separated school departments might exhibit, in different ways, very similar practices. Data from an ethnographic study of three secondary school geography departments in England are discussed through a concept of "isomorphism" (homogenising forces), drawn from neo-institutional theory. Similarities across…

Steroid isotopic standards for gas chromatography-combustion isotope ratio mass spectrometry (GCC-IRMS).

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Zhang, Ying; Tobias, Herbert J; Brenna, J Thomas

2009-03-01

Carbon isotope ratio (CIR) analysis of urinary steroids using gas chromatography-combustion isotope ratio mass spectrometry (GCC-IRMS) is a recognized test to detect illicit doping with synthetic testosterone. There are currently no universally used steroid isotopic standards (SIS). We adapted a protocol to prepare isotopically uniform steroids for use as a calibrant in GCC-IRMS that can be analyzed under the same conditions as used for steroids extracted from urine. Two separate SIS containing a mixture of steroids were created and coded CU/USADA 33-1 and CU/USADA 34-1, containing acetates and native steroids, respectively. CU/USADA 33-1 contains 5alpha-androstan-3beta-ol acetate (5alpha-A-AC), 5alpha-androstan-3alpha-ol-17-one acetate (androsterone acetate, A-AC), 5beta-androstan-3alpha-ol-11, 17-dione acetate (11-ketoetiocholanolone acetate, 11k-AC) and 5alpha-cholestane (Cne). CU/USADA 34-1 contains 5beta-androstan-3alpha-ol-17-one (etiocholanolone, E), 5alpha-androstan-3alpha-ol-17-one (androsterone, A), and 5beta-pregnane-3alpha, 20alpha-diol (5betaP). Each mixture was prepared and dispensed into a set of about 100 ampoules using a protocol carefully designed to minimize isotopic fractionation and contamination. A natural gas reference material, NIST RM 8559, traceable to the international standard Vienna PeeDee Belemnite (VPDB) was used to calibrate the SIS. Absolute delta(13)C(VPDB) and Deltadelta(13)C(VPDB) values from randomly selected ampoules from both SIS indicate uniformity of steroid isotopic composition within measurement reproducibility, SD(delta(13)C)<0.2 per thousand. This procedure for creation of isotopic steroid mixtures results in consistent standards with isotope ratios traceable to the relevant international reference material.

Regressão e crescimento do primogênito no processo de tornar-se irmão Firstborn's regression and growth in the process of becoming a sibling

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Débora Silva Oliveira

2013-03-01

Full Text Available Investigaram-se indicadores de regressão e crescimento do primogênito no processo de tornar-se irmão. Participaram três primogênitos pré-escolares no terceiro trimestre de gestação, aos 12 e 24 meses do irmão. Foi aplicado o Teste das Fábulas e realizada análise qualitativa de conteúdo. Os resultados revelaram regressão do primogênito na gestação materna e crescimento, aos 12 e aos 24 meses de idade do irmão. A regressão foi uma forma de enfrentar a chegada do irmão, enquanto que o crescimento revelou capacidade para conquistas ou custos de ser mais velho. Tanto a regressão quanto o crescimento oportunizaram um ir e vir saudável, fundamental para o desenvolvimento rumo à independência. Esses achados têm implicações para a pesquisa e para a clínica.Regression and growth indicators in the process of becoming a sibling were investigated. Three firstborns took part in the study during the first sibling's third trimester of pregnancy, and when the sibling was 12 and 24 months old, respectively. The Fables Test was used and a qualitative content analysis was carried out. Results revealed regression indicators during pregnancy. At 12 and 24 months there were growth indicators together with regression indicators. Regression was used by the firstborn for coping with the sibling's arrival while growth revealed the capacity for acquisitions or the costs of being an older sibling. Both regressive and growth manifestations enabled a healthy to and fro, which is fundamental for development towards independence. These findings have both research and clinical implications.

A new CF-IRMS system for quantifying stable isotopes of carbon monoxide from ice cores and small air samples

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Z. Wang

2010-10-01

Full Text Available We present a new analysis technique for stable isotope ratios (δ¹³C and δ¹⁸O of atmospheric carbon monoxide (CO from ice core samples. The technique is an online cryogenic vacuum extraction followed by continuous-flow isotope ratio mass spectrometry (CF-IRMS; it can also be used with small air samples. The CO extraction system includes two multi-loop cryogenic cleanup traps, a chemical oxidant for oxidation to CO₂, a cryogenic collection trap, a cryofocusing unit, gas chromatography purification, and subsequent injection into a Finnigan Delta Plus IRMS. Analytical precision of 0.2‰ (±1δ for δ¹³C and 0.6‰ (±1δ for δ¹⁸O can be obtained for 100 mL (STP air samples with CO mixing ratios ranging from 60 ppbv to 140 ppbv (~268–625 pmol CO. Six South Pole ice core samples from depths ranging from 133 m to 177 m were processed for CO isotope analysis after wet extraction. To our knowledge, this is the first measurement of stable isotopes of CO in ice core air.

Detecting animal by-product intake using stable isotope ratio mass spectrometry (IRMS).

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da Silva, D A F; Biscola, N P; Dos Santos, L D; Sartori, M M P; Denadai, J C; da Silva, E T; Ducatti, C; Bicudo, S D; Barraviera, B; Ferreira, R S

2016-11-01

Sheep are used in many countries as food and for manufacturing bioproducts. However, when these animals consume animal by-products (ABP), which is widely prohibited, there is a risk of transmitting scrapie - a fatal prion disease in human beings. Therefore, it is essential to develop sensitive methods to detect previous ABP intake to select safe animals for producing biopharmaceuticals. We used stable isotope ratio mass spectrometry (IRMS) for 13 C and 15 N to trace animal proteins in the serum of three groups of sheep: 1 - received only vegetable protein (VP) for 89 days; 2 - received animal and vegetable protein (AVP); and 3 - received animal and vegetable protein with animal protein subsequently removed (AVPR). Groups 2 and 3 received diets with 30% bovine meat and bone meal (MBM) added to a vegetable diet (from days 16-89 in the AVP group and until day 49 in the AVPR group, when MBM was removed). The AVPR group showed 15 N equilibrium 5 days after MBM removal (54th day). Conversely, 15 N equilibrium in the AVP group occurred 22 days later (76th day). The half-life differed between these groups by 3.55 days. In the AVPR group, 15 N elimination required 53 days, which was similar to this isotope's incorporation time. Turnover was determined based on natural 15 N signatures. IRMS followed by turnover calculations was used to evaluate the time period for the incorporation and elimination of animal protein in sheep serum. The δ 13 C and δ 15 N values were used to track animal protein in the diet. This method is biologically and economically relevant for the veterinary field because it can track protein over time or make a point assessment of animal feed with high sensitivity and resolution, providing a low-cost analysis coupled with fast detection. Isotopic profiles could be measured throughout the experimental period, demonstrating the potential to use the method for traceability and certification assessments. Copyright © 2016 Elsevier Ltd. All rights reserved.

Production of [Formula: see text] and [Formula: see text] in proton-proton collisions at [Formula: see text] 7 TeV.

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Cheynis, B; Chibante Barroso, V; Chinellato, D D; Chochula, P; Chojnacki, M; Choudhury, S; Christakoglou, P; Christensen, C H; Christiansen, P; Chujo, T; Chung, S U; Cicalo, C; Cifarelli, L; Cindolo, F; Cleymans, J; Colamaria, F; Colella, D; Collu, A; Colocci, M; Conesa Balbastre, G; Conesa Del Valle, Z; Connors, M E; Contreras, J G; Cormier, T M; Corrales Morales, Y; Cortese, P; Cortés Maldonado, I; Cosentino, M R; Costa, F; Crochet, P; Cruz Albino, R; Cuautle, E; Cunqueiro, L; Dainese, A; Dang, R; Danu, A; Das, D; Das, I; Das, K; Das, S; Dash, A; Dash, S; De, S; Delagrange, H; Deloff, A; Dénes, E; D'Erasmo, G; De Caro, A; de Cataldo, G; de Cuveland, J; De Falco, A; De Gruttola, D; De Marco, N; De Pasquale, S; de Rooij, R; Diaz Corchero, M A; Dietel, T; Dillenseger, P; Divià, R; Di Bari, D; Di Liberto, S; Di Mauro, A; Di Nezza, P; Djuvsland, Ø; Dobrin, A; Dobrowolski, T; Domenicis Gimenez, D; Dönigus, B; Dordic, O; Dørheim, S; Dubey, A K; Dubla, A; Ducroux, L; Dupieux, P; Dutta Majumdar, A K; Hilden, T E; Ehlers, R J; Elia, D; Engel, H; Erazmus, B; Erdal, H A; Eschweiler, D; Espagnon, B; Esposito, M; Estienne, M; Esumi, S; Evans, D; Evdokimov, S; Fabris, D; Faivre, J; Falchieri, D; Fantoni, A; Fasel, M; Fehlker, D; Feldkamp, L; Felea, D; Feliciello, A; Feofilov, G; Ferencei, J; Fernández Téllez, A; Ferreiro, E G; Ferretti, A; Festanti, A; Figiel, J; Figueredo, M A S; Filchagin, S; Finogeev, D; Fionda, F M; Fiore, E M; Floratos, E; Floris, M; Foertsch, S; Foka, P; Fokin, S; Fragiacomo, E; Francescon, A; Frankenfeld, U; Fuchs, U; Furget, C; Furs, A; Fusco Girard, M; Gaardhøje, J J; Gagliardi, M; Gago, A M; Gallio, M; Gangadharan, D R; Ganoti, P; Gao, C; Garabatos, C; Garcia-Solis, E; Gargiulo, C; Garishvili, I; Gerhard, J; Germain, M; Gheata, A; Gheata, M; Ghidini, B; Ghosh, P; Ghosh, S K; Gianotti, P; Giubellino, P; Gladysz-Dziadus, E; Glässel, P; Gomez Ramirez, A; González-Zamora, P; Gorbunov, S; Görlich, L; Gotovac, S; Graczykowski, L K; Grelli, A; Grigoras, A; Grigoras, C; Grigoriev, V; Grigoryan, A; Grigoryan, S; Grinyov, B; Grion, N; Grosse-Oetringhaus, J F; Grossiord, J-Y; Grosso, R; Guber, F; Guernane, R; Guerzoni, B; Guilbaud, M; Gulbrandsen, K; Gulkanyan, H; Gumbo, M; Gunji, T; Gupta, A; Gupta, R; Khan, K H; Haake, R; Haaland, Ø; Hadjidakis, C; Haiduc, M; Hamagaki, H; Hamar, G; Hanratty, L D; Hansen, A; Harris, J W; Hartmann, H; Harton, A; Hatzifotiadou, D; Hayashi, S; Heckel, S T; Heide, M; Helstrup, H; Herghelegiu, A; Herrera Corral, G; Hess, B A; Hetland, K F; Hippolyte, B; Hladky, J; Hristov, P; Huang, M; Humanic, T J; Hussain, N; Hussain, T; Hutter, D; Hwang, D S; Ilkaev, R; Ilkiv, I; Inaba, M; Innocenti, G M; Ionita, C; Ippolitov, M; Irfan, M; Ivanov, M; Ivanov, V; Jachołkowski, A; Jacobs, P M; Jahnke, C; Jang, H J; Janik, M A; Jayarathna, P H S Y; Jena, C; Jena, S; Jimenez Bustamante, R T; Jones, P G; Jung, H; Jusko, A; Kadyshevskiy, V; Kalinak, P; Kalweit, A; Kamin, J; Kang, J H; Kaplin, V; Kar, S; Karasu Uysal, A; Karavichev, O; Karavicheva, T; Karpechev, E; Kebschull, U; Keidel, R; Keijdener, D L D; Svn, M Keil; Khan, M M; Khan, P; Khan, S A; Khanzadeev, A; Kharlov, Y; Kileng, B; Kim, B; Kim, D W; Kim, D J; Kim, J S; Kim, M; Kim, M; Kim, S; Kim, T; Kirsch, S; Kisel, I; Kiselev, S; Kisiel, A; Kiss, G; Klay, J L; Klein, J; Klein-Bösing, C; Kluge, A; Knichel, M L; Knospe, A G; Kobdaj, C; Kofarago, M; Köhler, M K; Kollegger, T; Kolojvari, A; Kondratiev, V; Kondratyeva, N; Konevskikh, A; Kovalenko, V; Kowalski, M; Kox, S; Koyithatta Meethaleveedu, G; Kral, J; Králik, I; Kravčáková, A; Krelina, M; Kretz, M; Krivda, M; Krizek, F; Kryshen, E; Krzewicki, M; Kučera, V; Kucheriaev, Y; Kugathasan, T; Kuhn, C; Kuijer, P G; Kulakov, I; Kumar, J; Kurashvili, P; Kurepin, A; Kurepin, A B; Kuryakin, A; Kushpil, S; Kweon, M J; Kwon, Y; Ladron de Guevara, P; Lagana Fernandes, C; Lakomov, I; Langoy, R; Lara, C; Lardeux, A; Lattuca, A; La Pointe, S L; La Rocca, P; Lea, R; Leardini, L; Lee, G R; Legrand, I; Lehnert, J; Lemmon, R C; Lenti, V; Leogrande, E; Leoncino, M; León Monzón, I; Lévai, P; Li, S; Lien, J; Lietava, R; Lindal, S; Lindenstruth, V; Lippmann, C; Lisa, M A; Ljunggren, H M; Lodato, D F; Loenne, P I; Loggins, V R; Loginov, V; Lohner, D; Loizides, C; Lopez, X; López Torres, E; Lu, X-G; Luettig, P; Lunardon, M; Luparello, G; Ma, R; Maevskaya, A; Mager, M; Mahapatra, D P; Mahmood, S M; Maire, A; Majka, R D; Malaev, M; Maldonado Cervantes, I; Malinina, L; Mal'Kevich, D; Malzacher, P; Mamonov, A; Manceau, L; Manko, V; Manso, F; Manzari, V; Marchisone, M; Mareš, J; Margagliotti, G V; Margotti, A; Marín, A; Markert, C; Marquard, M; Martashvili, I; Martin, N A; Martinengo, P; Martínez, M I; Martínez García, G; Martin Blanco, J; Martynov, Y; Mas, A; Masciocchi, S; Masera, M; Masoni, A; Massacrier, L; Mastroserio, A; Matyja, A; Mayer, C; Mazer, J; Mazzoni, M A; Meddi, F; Menchaca-Rocha, A; Meninno, E; Mercado Pérez, J; Meres, M; Miake, Y; Mikhaylov, K; Milano, L; Milosevic, J; Mischke, A; Mishra, A N; Miśkowiec, D; Mitra, J; Mitu, C M; Mlynarz, J; Mohammadi, N; Mohanty, B; Molnar, L; Montaño Zetina, L; Montes, E; Morando, M; Moreira De Godoy, D A; Moretto, S; Morreale, A; Morsch, A; Muccifora, V; Mudnic, E; Mühlheim, D; Muhuri, S; Mukherjee, M; Müller, H; Munhoz, M G; Murray, S; Musa, L; Musinsky, J; Nandi, B K; Nania, R; Nappi, E; Nattrass, C; Nayak, K; Nayak, T K; Nazarenko, S; Nedosekin, A; Nicassio, M; Niculescu, M; Niedziela, J; Nielsen, B S; Nikolaev, S; Nikulin, S; Nikulin, V; Nilsen, B S; Noferini, F; Nomokonov, P; Nooren, G; Norman, J; Nyanin, A; Nystrand, J; Oeschler, H; Oh, S; Oh, S K; Okatan, A; Okubo, T; Olah, L; Oleniacz, J; Oliveira Da Silva, A C; Onderwaater, J; Oppedisano, C; Ortiz Velasquez, A; Oskarsson, A; Otwinowski, J; Oyama, K; Ozdemir, M; Sahoo, P; Pachmayer, Y; Pachr, M; Pagano, P; Paić, G; Pajares, C; Pal, S K; Palmeri, A; Pant, D; Papikyan, V; Pappalardo, G S; Pareek, P; Park, W J; Parmar, S; Passfeld, A; Patalakha, D I; Paticchio, V; Paul, B; Pawlak, T; Peitzmann, T; Pereira Da Costa, H; Pereira De Oliveira Filho, E; Peresunko, D; Pérez Lara, C E; Pesci, A; Peskov, V; Pestov, Y; Petráček, V; Petran, M; Petris, M; Petrovici, M; Petta, C; Piano, S; Pikna, M; Pillot, P; Pinazza, O; Pinsky, L; Piyarathna, D B; Płoskoń, M; Planinic, M; Pluta, J; Pochybova, S; Podesta-Lerma, P L M; Poghosyan, M G; Pohjoisaho, E H O; Polichtchouk, B; Poljak, N; Pop, A; Porteboeuf-Houssais, S; Porter, J; Potukuchi, B; Prasad, S K; Preghenella, R; Prino, F; Pruneau, C A; Pshenichnov, I; Puccio, M; Puddu, G; Pujahari, P; Punin, V; Putschke, J; Qvigstad, H; Rachevski, A; Raha, S; Rajput, S; Rak, J; Rakotozafindrabe, A; Ramello, L; Raniwala, R; Raniwala, S; Räsänen, S S; Rascanu, B T; Rathee, D; Rauf, A W; Razazi, V; Read, K F; Real, J S; Redlich, K; Reed, R J; Rehman, A; Reichelt, P; Reicher, M; Reidt, F; Renfordt, R; Reolon, A R; Reshetin, A; Rettig, F; Revol, J-P; Reygers, K; Riabov, V; Ricci, R A; Richert, T; Richter, M; Riedler, P; Riegler, W; Riggi, F; Rivetti, A; Rocco, E; Rodríguez Cahuantzi, M; Rodriguez Manso, A; Røed, K; Rogochaya, E; Rohni, S; Rohr, D; Röhrich, D; Romita, R; Ronchetti, F; Ronflette, L; Rosnet, P; Rossi, A; Roukoutakis, F; Roy, A; Roy, C; Roy, P; Rubio Montero, A J; Rui, R; Russo, R; Ryabinkin, E; Ryabov, Y; Rybicki, A; Sadovsky, S; Šafařík, K; Sahlmuller, B; Sahoo, R; Sahu, P K; Saini, J; Sakai, S; Salgado, C A; Salzwedel, J; Sambyal, S; Samsonov, V; Sanchez Castro, X; Sánchez Rodríguez, F J; Šándor, L; Sandoval, A; Sano, M; Santagati, G; Sarkar, D; Scapparone, E; Scarlassara, F; Scharenberg, R P; Schiaua, C; Schicker, R; Schmidt, C; Schmidt, H R; Schuchmann, S; Schukraft, J; Schulc, M; Schuster, T; Schutz, Y; Schwarz, K; Schweda, K; Scioli, G; Scomparin, E; Scott, R; Segato, G; Seger, J E; Sekiguchi, Y; Selyuzhenkov, I; Senosi, K; Seo, J; Serradilla, E; Sevcenco, A; Shabetai, A; Shabratova, G; Shahoyan, R; Shangaraev, A; Sharma, A; Sharma, N; Sharma, S; Shigaki, K; Shtejer, K; Sibiriak, Y; Siddhanta, S; Siemiarczuk, T; Silvermyr, D; Silvestre, C; Simatovic, G; Singaraju, R; Singh, R; Singha, S; Singhal, V; Sinha, B C; Sinha, T; Sitar, B; Sitta, M; Skaali, T B; Skjerdal, K; Slupecki, M; Smirnov, N; Snellings, R J M; Søgaard, C; Soltz, R; Song, J; Song, M; Soramel, F; Sorensen, S; Spacek, M; Spiriti, E; Sputowska, I; Spyropoulou-Stassinaki, M; Srivastava, B K; Stachel, J; Stan, I; Stefanek, G; Steinpreis, M; Stenlund, E; Steyn, G; Stiller, J H; Stocco, D; Stolpovskiy, M; Strmen, P; Suaide, A A P; Sugitate, T; Suire, C; Suleymanov, M; Sultanov, R; Šumbera, M; Symons, T J M; Szabo, A; Szanto de Toledo, A; Szarka, I; Szczepankiewicz, A; Szymanski, M; Takahashi, J; Tangaro, M A; Tapia Takaki, J D; Tarantola Peloni, A; Tarazona Martinez, A; Tariq, M; Tarzila, M G; Tauro, A; Tejeda Muñoz, G; Telesca, A; Terasaki, K; Terrevoli, C; Thäder, J; Thomas, D; Tieulent, R; Timmins, A R; Toia, A; Trubnikov, V; Trzaska, W H; Tsuji, T; Tumkin, A; Turrisi, R; Tveter, T S; Ullaland, K; Uras, A; Usai, G L; Vajzer, M; Vala, M; Valencia Palomo, L; Vallero, S; Vande Vyvre, P; Van Der Maarel, J; Van Hoorne, J W; van Leeuwen, M; Vargas, A; Vargyas, M; Varma, R; Vasileiou, M; Vasiliev, A; Vechernin, V; Veldhoen, M; Velure, A; Venaruzzo, M; Vercellin, E; Vergara Limón, S; Vernet, R; Verweij, M; Vickovic, L; Viesti, G; Viinikainen, J; Vilakazi, Z; Villalobos Baillie, O; Vinogradov, A; Vinogradov, L; Vinogradov, Y; Virgili, T; Vislavicius, V; Viyogi, Y P; Vodopyanov, A; Völkl, M A; Voloshin, K; Voloshin, S A; Volpe, G; von Haller, B; Vorobyev, I; Vranic, D; Vrláková, J; Vulpescu, B; Vyushin, A; Wagner, B; Wagner, J; Wagner, V; Wang, M; Wang, Y; Watanabe, D; Weber, M; Weber, S G; Wessels, J P; Westerhoff, U; Wiechula, J; Wikne, J; Wilde, M; Wilk, G; Wilkinson, J; Williams, M C S; Windelband, B; Winn, M; Yaldo, C G; Yamaguchi, Y; Yang, H; Yang, P; Yang, S; Yano, S; Yasnopolskiy, S; Yi, J; Yin, Z; Yoo, I-K; Yushmanov, I; Zaccolo, V; Zach, C; Zaman, A; Zampolli, C; Zaporozhets, S; Zarochentsev, A; Závada, P; Zaviyalov, N; Zbroszczyk, H; Zgura, I S; Zhalov, M; Zhang, H; Zhang, X; Zhang, Y; Zhao, C; Zhigareva, N; Zhou, D; Zhou, F; Zhou, Y; Zhuo, Zhou; Zhu, H; Zhu, J; Zhu, X; Zichichi, A; Zimmermann, A; Zimmermann, M B; Zinovjev, G; Zoccarato, Y; Zyzak, M

The production of the strange and double-strange baryon resonances ([Formula: see text], [Formula: see text]) has been measured at mid-rapidity ([Formula: see text][Formula: see text]) in proton-proton collisions at [Formula: see text] [Formula: see text] 7 TeV with the ALICE detector at the LHC. Transverse momentum spectra for inelastic collisions are compared to QCD-inspired models, which in general underpredict the data. A search for the [Formula: see text] pentaquark, decaying in the [Formula: see text] channel, has been carried out but no evidence is seen.

Ammonia IRMS-TPD measurements on Brønsted acidity of proton-formed SAPO-34.

Science.gov (United States)

Suzuki, Katsuki; Nishio, Takuma; Katada, Naonobu; Sastre, German; Niwa, Miki

2011-02-28

By utilizing the advantages of a combined method of IRMS-TPD of ammonia and DFT calculations, the solid acidity of HSAPO-34 was studied. The number, strength and structure of the Brønsted OH were measured experimentally. The quantitative measurements and DFT calculations supported the identification of Brønsted OH to account for the generation model of the Brønsted OH primarily located in the edge of the Si domain (island). The acid strength of SAPO-34 was slightly weaker than that of chabazite, a zeolite with the same structure. Thus, some important insights were obtained to understand the acid site generation of SAPO-34.

Os contos dos Irmãos Grimm e o seu poder questionador

Directory of Open Access Journals (Sweden)

Fernando Azeved

2014-06-01

Full Text Available Este ensaio analisa a dimensão questionadora subjacente a alguns contos dos Irmãos Grimm, salientando que, muitos destes textos, pela sua especificidade e pelo seu funcionamento pragmático, comportam uma não negligenciável capacidade perlocutiva. Com efeito, no corpus selecionado verifica-se uma atenção concedida a personagens simbolicamente destituídas de voz ou de capacidade de ação, mostrando-se que elas podem, se assim o desejarem, alcançar sempre uma certa ordem simbólica, desde que realizem um determinado esforço, superando um conjunto de provas ou de obstáculos. Deste modo, estes textos ensinam os seus leitores a acreditaram no poder da palavra e na capacidade desta em transformar o mundo.

2H NMR and 13C-IRMS analyses of acetic acid from vinegar, 18O-IRMS analysis of water in vinegar: international collaborative study report.

Science.gov (United States)

Thomas, Freddy; Jamin, Eric

2009-09-01

An international collaborative study of isotopic methods applied to control the authenticity of vinegar was organized in order to support the recognition of these procedures as official methods. The determination of the 2H/1H ratio of the methyl site of acetic acid by SNIF-NMR (site-specific natural isotopic fractionation-nuclear magnetic resonance) and the determination of the 13C/12C ratio, by IRMS (isotope ratio mass spectrometry) provide complementary information to characterize the botanical origin of acetic acid and to detect adulterations of vinegar using synthetic acetic acid. Both methods use the same initial steps to recover pure acetic acid from vinegar. In the case of wine vinegar, the determination of the 18O/16O ratio of water by IRMS allows to differentiate wine vinegar from vinegars made from dried grapes. The same set of vinegar samples was used to validate these three determinations. The precision parameters of the method for measuring delta13C (carbon isotopic deviation) were found to be similar to the values previously obtained for similar methods applied to wine ethanol or sugars extracted from fruit juices: the average repeatability (r) was 0.45 per thousand, and the average reproducibility (R) was 0.91 per thousand. As expected from previous in-house study of the uncertainties, the precision parameters of the method for measuring the 2H/1H ratio of the methyl site were found to be slightly higher than the values previously obtained for similar methods applied to wine ethanol or fermentation ethanol in fruit juices: the average repeatability was 1.34 ppm, and the average reproducibility was 1.62 ppm. This precision is still significantly smaller than the differences between various acetic acid sources (delta13C and delta18O) and allows a satisfactory discrimination of vinegar types. The precision parameters of the method for measuring delta18O were found to be similar to the values previously obtained for other methods applied to wine and

2H NMR and 13C-IRMS analyses of acetic acid from vinegar, 18O-IRMS analysis of water in vinegar: International collaborative study report

International Nuclear Information System (INIS)

Thomas, Freddy; Jamin, Eric

2009-01-01

An international collaborative study of isotopic methods applied to control the authenticity of vinegar was organized in order to support the recognition of these procedures as official methods. The determination of the 2 H/ 1 H ratio of the methyl site of acetic acid by SNIF-NMR (site-specific natural isotopic fractionation-nuclear magnetic resonance) and the determination of the 13 C/ 12 C ratio, by IRMS (isotope ratio mass spectrometry) provide complementary information to characterize the botanical origin of acetic acid and to detect adulterations of vinegar using synthetic acetic acid. Both methods use the same initial steps to recover pure acetic acid from vinegar. In the case of wine vinegar, the determination of the 18 O/ 16 O ratio of water by IRMS allows to differentiate wine vinegar from vinegars made from dried grapes. The same set of vinegar samples was used to validate these three determinations. The precision parameters of the method for measuring δ 13 C (carbon isotopic deviation) were found to be similar to the values previously obtained for similar methods applied to wine ethanol or sugars extracted from fruit juices: the average repeatability (r) was 0.45 per mille , and the average reproducibility (R) was 0.91 per mille . As expected from previous in-house study of the uncertainties, the precision parameters of the method for measuring the 2 H/ 1 H ratio of the methyl site were found to be slightly higher than the values previously obtained for similar methods applied to wine ethanol or fermentation ethanol in fruit juices: the average repeatability was 1.34 ppm, and the average reproducibility was 1.62 ppm. This precision is still significantly smaller than the differences between various acetic acid sources (δ 13 C and δ 18 O) and allows a satisfactory discrimination of vinegar types. The precision parameters of the method for measuring δ 18 O were found to be similar to the values previously obtained for other methods applied to wine and

Information resources management long-range plan, FY1994--1998

Energy Technology Data Exchange (ETDEWEB)

1993-04-01

This document describes IRM activities and the information technology resources and capabilities of the Department, the future requirements, and the strategies and plans to satisfy the identified requirements. The long-range planning process provides the systematic means to meet this objective and assists the Department in assuring that information technology (IT) support is provided in an efficient, effective, and timely manner so that its programmatic missions can be accomplished. Another important objective of the Plan is to promote better understanding, both within and external to the Department, of its IT environment, requirements, issues, and recommended solutions. This DOE IRM Plan takes into consideration the IRM requirements of approximately 50 different sites. The annual long-range planning cycle for supporting this Plan was initiated by a Call in August 1991 for site plans to be submitted in February 1992 by those Departmental components and contractors with major IRM requirements.

Information resources management long-range plan, FY1994--1998

International Nuclear Information System (INIS)

1993-04-01

This document describes IRM activities and the information technology resources and capabilities of the Department, the future requirements, and the strategies and plans to satisfy the identified requirements. The long-range planning process provides the systematic means to meet this objective and assists the Department in assuring that information technology (IT) support is provided in an efficient, effective, and timely manner so that its programmatic missions can be accomplished. Another important objective of the Plan is to promote better understanding, both within and external to the Department, of its IT environment, requirements, issues, and recommended solutions. This DOE IRM Plan takes into consideration the IRM requirements of approximately 50 different sites. The annual long-range planning cycle for supporting this Plan was initiated by a Call in August 1991 for site plans to be submitted in February 1992 by those Departmental components and contractors with major IRM requirements

Interação entre irmãos: deficiência mental, idade e apoio social da família Siblings' interaction: mental disability, age and family social support

Directory of Open Access Journals (Sweden)

Célia Cristina Nunes

2008-01-01

Full Text Available Os objetivos deste estudo foram: (a caracterizar a interação entre díades de irmãos, divididas em dois grupos - G1, com o irmão deficiente mental pré-adolescente, e G2, com esse irmão adulto; (b comparar os desempenhos dos grupos nas interações; e (c avaliar diferenças entre os grupos nas interações, considerando o apoio social da família. Foram realizadas sessões de observação de interações, e aplicação de instrumentos de auto-relato; os cuidadores responderam escalas para avaliação do apoio social. Os resultados sugeriram diferença no comportamento de ajudante do irmão com desenvolvimento típico, com taxa de ocorrência maior para G1. Nas escalas, houve diferença estatisticamente significativa na Escala de Apoio à Maternidade/Paternidade, revelando-se menor apoio para G1. Especula-se que, como as famílias do G1 recebem menor apoio deste nível, há maior demanda de ajuda requerida pelo filho deficiente, que pode ser suprida pelos irmãos menores com desenvolvimento típico, que desempenham o papel de ajudante em maior escala que os adultos.The purpose of the present study was: (a To describe the relationship in sibling's dyads, separated in two groups - G1, with pre-adolescent mentally retarded sibling, and G2, with this adult sibling; (b To compare the performance of both groups in the interactions; and (3 To evaluate differences in the relationships between the groups when family social support is taken into account. Sessions of sibling's interactions were videotaped, and self-report instruments were used. The caretakers answered scales of social support. Results suggested differences concerning the behavior of the helper of the sibling with characteristic development, with highest occurrence in G1. Scales' results indicated statistically significant difference for the Parenting Support from Family/Friends Scale, showing less support for G1. It is possible to suggest that because families from G1 have less support

Stable Carbon Isotope Ratio (δ13C Measurement of Graphite Using EA-IRMS System

Directory of Open Access Journals (Sweden)

Andrius Garbaras

2015-06-01

Full Text Available δ13C values in non-irradiated natural graphite were measured. The measurements were carried out using an elemental analyzer combined with stable isotope ratio mass spectrometer (EA-IRMS. The samples were prepared with ground and non-ground graphite, the part of which was mixed with Mg (ClO42. The best combustion of graphite in the oxidation furnace of the elemental analyzer was achieved when the amount of pulverized graphite ranged from 200 to 490 µg and the mass ratio C:Mg(ClO42 was approximately 1:10. The method for the graphite burning avoiding the isotope fractionation is proposed.DOI: http://dx.doi.org/10.5755/j01.ms.21.2.6873

Granulome à cholestérine de l\\'apex pétreux. Intérêt de l\\'irm ...

African Journals Online (AJOL)

Observation : le patient âgé de 43 ans a présenté de façon progressive une hypoacousie droite, des acouphènes, une sensation d\\'oreille pleine et une hyposensibilité de l\\'hémiface droite. Une audiométrie, un examen scanographique (TDM) et une IRM en séquence pondéré en T1 et T2 cérébrale ont été réalisées.

Optimization of on-line hydrogen stable isotope ratio measurements of halogen- and sulfur-bearing organic compounds using elemental analyzer-chromium/high-temperature conversion isotope ratio mass spectrometry (EA-Cr/HTC-IRMS).

Science.gov (United States)

Gehre, Matthias; Renpenning, Julian; Geilmann, Heike; Qi, Haiping; Coplen, Tyler B; Kümmel, Steffen; Ivdra, Natalija; Brand, Willi A; Schimmelmann, Arndt

2017-03-30

Accurate hydrogen isotopic analysis of halogen- and sulfur-bearing organics has not been possible with traditional high-temperature conversion (HTC) because the formation of hydrogen-bearing reaction products other than molecular hydrogen (H 2 ) is responsible for non-quantitative H 2 yields and possible hydrogen isotopic fractionation. Our previously introduced, new chromium-based EA-Cr/HTC-IRMS (Elemental Analyzer-Chromium/High-Temperature Conversion Isotope Ratio Mass Spectrometry) technique focused primarily on nitrogen-bearing compounds. Several technical and analytical issues concerning halogen- and sulfur-bearing samples, however, remained unresolved and required further refinement of the reactor systems. The EA-Cr/HTC reactor was substantially modified for the conversion of halogen- and sulfur-bearing samples. The performance of the novel conversion setup for solid and liquid samples was monitored and optimized using a simultaneously operating dual-detection system of IRMS and ion trap MS. The method with several variants in the reactor, including the addition of manganese metal chips, was evaluated in three laboratories using EA-Cr/HTC-IRMS (on-line method) and compared with traditional uranium-reduction-based conversion combined with manual dual-inlet IRMS analysis (off-line method) in one laboratory. The modified EA-Cr/HTC reactor setup showed an overall H 2 -recovery of more than 96% for all halogen- and sulfur-bearing organic compounds. All results were successfully normalized via two-point calibration with VSMOW-SLAP reference waters. Precise and accurate hydrogen isotopic analysis was achieved for a variety of organics containing F-, Cl-, Br-, I-, and S-bearing heteroelements. The robust nature of the on-line EA-Cr/HTC technique was demonstrated by a series of 196 consecutive measurements with a single reactor filling. The optimized EA-Cr/HTC reactor design can be implemented in existing analytical equipment using commercially available material and

Oxygen isotope analysis of phosphate: improved precision using TC/EA CF-IRMS.

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LaPorte, D F; Holmden, C; Patterson, W P; Prokopiuk, T; Eglington, B M

2009-06-01

Oxygen isotope values of biogenic apatite have long demonstrated considerable promise for paleothermometry potential because of the abundance of material in the fossil record and greater resistance of apatite to diagenesis compared to carbonate. Unfortunately, this promise has not been fully realized because of relatively poor precision of isotopic measurements, and exceedingly small size of some substrates for analysis. Building on previous work, we demonstrate that it is possible to improve precision of delta18O(PO4) measurements using a 'reverse-plumbed' thermal conversion elemental analyzer (TC/EA) coupled to a continuous flow isotope ratio mass spectrometer (CF-IRMS) via a helium stream [Correction made here after initial online publication]. This modification to the flow of helium through the TC/EA, and careful location of the packing of glassy carbon fragments relative to the hot spot in the reactor, leads to narrower, more symmetrically distributed CO elution peaks with diminished tailing. In addition, we describe our apatite purification chemistry that uses nitric acid and cation exchange resin. Purification chemistry is optimized for processing small samples, minimizing isotopic fractionation of PO4(-3) and permitting Ca, Sr and Nd to be eluted and purified further for the measurement of delta44Ca and 87Sr/86Sr in modern biogenic apatite and 143Nd/144Nd in fossil apatite. Our methodology yields an external precision of +/- 0.15 per thousand (1sigma) for delta18O(PO4). The uncertainty is related to the preparation of the Ag3PO4 salt, conversion to CO gas in a reversed-plumbed TC/EA, analysis of oxygen isotopes using a CF-IRMS, and uncertainty in constructing calibration lines that convert raw delta18O data to the VSMOW scale. Matrix matching of samples and standards for the purpose of calibration to the VSMOW scale was determined to be unnecessary. Our method requires only slightly modified equipment that is widely available. This fact, and the

Sequence spaces [Formula: see text] and [Formula: see text] with application in clustering.

Science.gov (United States)

Khan, Mohd Shoaib; Alamri, Badriah As; Mursaleen, M; Lohani, Qm Danish

2017-01-01

Distance measures play a central role in evolving the clustering technique. Due to the rich mathematical background and natural implementation of [Formula: see text] distance measures, researchers were motivated to use them in almost every clustering process. Beside [Formula: see text] distance measures, there exist several distance measures. Sargent introduced a special type of distance measures [Formula: see text] and [Formula: see text] which is closely related to [Formula: see text]. In this paper, we generalized the Sargent sequence spaces through introduction of [Formula: see text] and [Formula: see text] sequence spaces. Moreover, it is shown that both spaces are BK -spaces, and one is a dual of another. Further, we have clustered the two-moon dataset by using an induced [Formula: see text]-distance measure (induced by the Sargent sequence space [Formula: see text]) in the k-means clustering algorithm. The clustering result established the efficacy of replacing the Euclidean distance measure by the [Formula: see text]-distance measure in the k-means algorithm.

High-precision 13C and 18O measurements by continuous flow-isotope ratio mass spectrometry (CF-IRMS) in Romanian wines characterization

International Nuclear Information System (INIS)

Costinel, Diana; Ionete, Roxana; Vremera, Raluca; Stanciu, Vasile

2008-01-01

Wines characterization is an important problem to which isotopic analysis by continuous flow- IRMS has made a significant contribution. The use of mass spectrometry (MS) to determine the ratios of stable isotopes in bio-molecules now provides the means to prove the botanical and geographical origin of a wide variety of foodstuffs - and therefore, to authenticate and eliminate fraud. There is a strong need for reliable and validated methods to ensure compliance with such regulation and to protect the interests of the consumer. The right to producing wines with an appellation of origin is guaranteed by the Ministry of Agriculture, based on proposals made by the National Office of Vine and Wine (starting with the 1993 vintage year). The Ministry of Agriculture, the National Office for Vine and Wine, and the National Research Institute grants the authentication of the wines with appellation of origin. The present paper emphasize the isotopic analysis for 18 O/ 16 O and 13 C/ 12 C from wines, using a new generation Isotope Ratio MS, CF-IRMS Delta V Plus, coupled with three flexible continuous flow preparation devices (GasBench II and TC Elemental Analyser). (authors)

IRMS to study a common cocaine cutting agent: phenacetin.

Science.gov (United States)

Ladroue, Virginie; Dujourdy, Laurence; Besacier, Fabrice; Jame, Patrick

2017-03-01

Phenacetin is a pharmaceutical closely related to acetaminophen that has been banned in France for a long time due to its nephritic and carcinogenic adverse effects. It frequently appears in cocaine seizures as a cutting agent. Following both sanitary and intelligence motivations, this molecule was chosen for this study, and stable isotopes seemed to be the most appropriate tool. A total of 228 seized samples were collected over a 6-year period, and 8 standards of known origin were purchased. They were submitted to gas chromatography (GC) or elemental analysis - isotope ratio mass spectrometry (EA-IRMS) measurements, depending on their complexity. Stable isotope ratios of carbon, hydrogen, and nitrogen for a part of the sample set, were acquired. The isotopic values of phenacetin standards acquired from various providers located worldwide are quite spread, which indicates that stable isotopes could be used to discriminate manufacturers. However, the measured values of most of the seized samples are concentrated in a narrow range, tending to demonstrate that phenacetin is smuggled from a single source or similar ones. Consequently, stable isotopes could only be used to exclude that several samples come from a common source. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

The Eighth Stage of Information Management: Information Resources Management (IRM) vs. Knowledge Management (KM), and the Chief Information Officer (CIO) vs. the Chief Knowledge Officer (CKO).

Science.gov (United States)

Chen, Rui

1998-01-01

Describes the characteristics of the transfer point of information management to knowledge management (KM), what information resources management (IRM) does, and compares information and knowledge management and the roles of chief information officer (CIO) and chief knowledge officer (CKO). (PEN)

Rastreamento de sinais e sintomas de transtornos do espectro do autismo em irmãos Screening for signs and symptoms of autism spectrum disorders in siblings

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Tatiana Pontrelli Mecca

2011-01-01

Full Text Available Os transtornos globais do desenvolvimento (TGD são caracterizados por anormalidades qualitativas e abrangentes em três domínios do desenvolvimento: interação social recíproca, comunicação e presença de um repertório comportamental de interesses restritos, repetitivo e estereotipado. Estudos genéticos têm identificado a recorrência de TGD numa mesma família. O presente estudo teve por objetivo rastrear a ocorrência de sinais e sintomas de TGD em irmãos de indivíduos com esse diagnóstico. Participaram do estudo 25 sujeitos provenientes de 19 famílias. A coleta de dados foi realizada mediante a utilização da versão brasileira do Autism Screening Questionnaire (ASQ, ou Questionário de Comportamento e Comunicação Social. Foram confirmados dois casos de irmãos com TGD (10,52% dos casos, sendo um irmão gêmeo monozigótico e um irmão de um probando com diagnóstico de síndrome de Asperger. Os dados apontam para taxas mais elevadas do que aquelas descritas na literatura (2-6% e se aproximam dos achados que relatam 10% de recorrência familiar em gêmeos dizigóticos. Esse resultado fornece evidências de possíveis fatores neurogenéticos para explicar a ocorrência de TGD nos familiares dos probandos estudados e salienta a necessidade de efetuar o rastreamento desse transtorno não só na criança avaliada, mas também em seus irmãos.Pervasive developmental disorders (PDD are characterized by comprehensive and qualitative abnormalities affecting three areas of development: reciprocal social interaction, communication, and a repetitive, stereotyped behavioral repertoire, of limited interests. Genetic studies have identified the recurrence of PDD in the same family. The present study aimed to trace the occurrence of signs and symptoms of PDD in the siblings of patients with this diagnosis. The study included 25 subjects from 19 families. Data collection was performed using the Brazilian version of the Autism Screening

Testing of an automated online EA-IRMS method for fast and simultaneous carbon content and stable isotope measurement of aerosol samples

Science.gov (United States)

Major, István; Gyökös, Brigitta; Túri, Marianna; Futó, István; Filep, Ágnes; Hoffer, András; Molnár, Mihály

2016-04-01

Comprehensive atmospheric studies have demonstrated that carbonaceous aerosol is one of the main components of atmospheric particulate matter over Europe. Various methods, considering optical or thermal properties, have been developed for quantification of the accurate amount of both organic and elemental carbon constituents of atmospheric aerosol. The aim of our work was to develop an alternative fast and easy method for determination of the total carbon content of individual aerosol samples collected on prebaked quartz filters whereby the mass and surface concentration becomes simply computable. We applied the conventional "elemental analyzer (EA) coupled online with an isotope ratio mass spectrometer (IRMS)" technique which is ubiquitously used in mass spectrometry. Using this technique we are able to measure simultaneously the carbon stable isotope ratio of the samples, as well. During the developing process, we compared the EA-IRMS technique with an off-line catalytic combustion method worked out previously at Hertelendi Laboratory of Environmental Studies (HEKAL). We tested the combined online total carbon content and stable isotope ratio measurement both on standard materials and real aerosol samples. Regarding the test results the novel method assures, on the one hand, at least 95% of carbon recovery yield in a broad total carbon mass range (between 100 and 3000 ug) and, on the other hand, a good reproducibility of stable isotope measurements with an uncertainty of ± 0.2 per mill. Comparing the total carbon results obtained by the EA-IRMS and the off-line catalytic combustion method we found a very good correlation (R2=0.94) that proves the applicability of both preparation method. Advantages of the novel method are the fast and simplified sample preparation steps and the fully automated, simultaneous carbon stable isotope ratio measurement processes. Furthermore stable isotope ratio results can effectively be applied in the source apportionment

Origin of Xylitol in Chewing Gum: A Compound-Specific Isotope Technique for the Differentiation of Corn- and Wood-Based Xylitol by LC-IRMS.

Science.gov (United States)

Köster, Daniel; Wolbert, Jens-Benjamin; Schulte, Marcel S; Jochmann, Maik A; Schmidt, Torsten C

2018-02-28

The sugar replacement compound xylitol has gained increasing attention because of its use in many commercial food products, dental-hygiene articles, and pharmaceuticals. It can be classified by the origin of the raw material used for its production. The traditional "birch xylitol" is considered a premium product, in contrast to xylitol produced from agriculture byproducts such as corn husks or sugar-cane straw. Bulk stable-isotope analysis (BSIA) and compound-specific stable-isotope analysis (CSIA) by liquid-chromatography isotope-ratio mass spectrometry (LC-IRMS) of chewing-gum extracts were used to determine the δ 13 C isotope signatures for xylitol. These were applied to elucidate the original plant type the xylitol was produced from on the basis of differences in isotope-fractionation processes of photosynthetic CO 2 fixation. For the LC-IRMS analysis, an organic-solvent-free extraction protocol and HPLC method for the separation of xylitol from different artificial sweeteners and sugar-replacement compounds was successfully developed and applied to the analysis of 21 samples of chewing gum, from which 18 could be clearly related to the raw-material plant class.

Extruder ile Pişirme Yönteminin Gıda Bileşim Öğeleri

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Nevzat Artık

2015-02-01

Full Text Available Gıdalara uygulanan diğer ısıl işlemler gibi extruder ile pişirme yönteminde yararlı ve zararlı etkileri birlikte söz konusudur. Bu yöntemin yararlı etkisi; gıdanın özelliklerini olumsuz etkileyen faktörlerin elemine edilmesi; olumsuz etkisi ise, proteinler ile şekerler arasında oluşan Maillard tepkimesidir. Anılan tepkime ile proteinlerin besleyici niteliği azalmaktadır. Ayrıca ısıl işlem nedeniyle vitamin kayıpları söz konusu olmaktadır (Bjorck ve Asp, 1982.

High-precision determination of 18O/16O ratios of silver phosphate by EA-pyrolysis-IRMS continuous flow technique.

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Lécuyer, Christophe; Fourel, François; Martineau, François; Amiot, Romain; Bernard, Aurélien; Daux, Valérie; Escarguel, Gilles; Morrison, John

2007-01-01

A high-precision, and rapid on-line method for oxygen isotope analysis of silver phosphate is presented. The technique uses high-temperature elemental analyzer (EA)-pyrolysis interfaced in continuous flow (CF) mode to an isotopic ratio mass spectrometer (IRMS). Calibration curves were generated by synthesizing silver phosphate with a 13 per thousand spread in delta(18)O values. Calibration materials were obtained by reacting dissolved potassium dihydrogen phosphate (KH(2)PO(4)) with water samples of various oxygen isotope compositions at 373 K. Validity of the method was tested by comparing the on-line results with those obtained by classical off-line sample preparation and dual inlet isotope measurement. In addition, silver phosphate precipitates were prepared from a collection of biogenic apatites with known delta(18)O values ranging from 12.8 to 29.9 per thousand (V-SMOW). Reproducibility of +/- 0.2 per thousand was obtained by the EA-Py-CF-IRMS method for sample sizes in the range 400-500 microg. Both natural and synthetic samples are remarkably well correlated with conventional (18)O/(16)O determinations. Silver phosphate is a very stable material and easy to degas and, thus, could be considered as a good candidate to become a reference material for the determination of (18)O/(16)O ratios of phosphate by high-temperature pyrolysis. Copyright 2006 John Wiley & Sons, Ltd.

Application of gas chromatography-mass spectrometry/combustion/isotope ratio mass spectrometry (GC-MS/C/IRMS) to detect the abuse of 17β-estradiol in cattle.

Science.gov (United States)

Janssens, Geert; Mangelinckx, Sven; Courtheyn, Dirk; Prévost, Stéphanie; De Poorter, Geert; De Kimpe, Norbert; Le Bizec, Bruno

2013-07-31

Although the ability to differentiate between endogenous steroids and synthetic homologues on the basis of their (13)C/(12)C isotopic ratio has been known for over a decade, this technique has been scarcely implemented for food safety purposes. In this study, a method was developed using gas chromatography-mass spectrometry/combustion/isotope ratio mass spectrometry (GC-MS/C/IRMS) to demonstrate the abuse of 17β-estradiol in cattle, by comparison of the (13)C/(12)C ratios of the main metabolite 17α-estradiol and an endogenous reference compound (ERC), 5-androstene-3β,17α-diol, in bovine urine. The intermediate precisions were determined as 0.46 and 0.26‰ for 5-androstene-3β,17α-diol and 17α-estradiol, respectively. This is, to the authors' knowledge, the first reported use of GC-MS/C/IRMS for the analysis of steroid compounds for food safety issues.

Authenticity determination of honeys with non-extractable proteins by means of elemental analyzer (EA) and liquid chromatography (LC) coupled to isotope ratio mass spectroscopy (IRMS).

Science.gov (United States)

Dong, Hao; Xiao, Kaijun; Xian, Yanping; Wu, Yuluan

2018-02-01

The present work aims to systematically demonstrate the authenticity of honeys with non-extractable proteins for the first time, by means of EA-IRMS and LC-IRMS. Fifty-three pure honeys of various botanical and geographical origins were studied and a criterion on the basis of the stable carbon isotope ratio characterization of total honey and the main sugars was established for pure honeys. Parameters such as δ 13 C values of total honey and the main sugars were well utilized to identify honeys with non-extractable proteins. Thirty-five honeys from which protein could not be extracted were all identified as adulterated with C-4 sugars or C-3 sugars. The use of isotopic compositions and some systematic differences permit the honeys with non-extractable proteins to be reliably identified. The findings obtained in this work could supplement the AOAC 998.12 C-4 sugar method, with regard to honeys from which protein cannot be extracted. Copyright © 2017 Elsevier Ltd. All rights reserved.

Associação de miopatia com ataxia e piramidalismo: estudo de dois irmãos

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Newra Tellechea Rotta

1974-09-01

Full Text Available São estudados os casos de dois irmãos examinados em Serviço de Neurologia Infantil por apresentarem dificuldade para manter o equilíbrio estático e dinâmico. Ao exame foi assinalado déficit estrutural, deficiência mental, distrofia muscular, síndrome piramidal e síndrome cerebelar. Os casos foram estudados do ponto de vista clínico, laboratorial, radiológico, eletromiográfico, psicológico e genético. É feita a discussão diagnóstica considerando miopatia autossômica recessiva da cintura pélvica e miopatia ocular associada a ataxia.

Apport de l’IRM dans la prise en charge des compressions médullaires lentes non traumatiques

Science.gov (United States)

Badji, Nfally; Deme, Hamidou; Akpo, Geraud; Ndong, Boucar; Toure, Mouhamadou Hamine; Diop, Sokhna Ba; Niang, El Hadji

2016-01-01

Les compressions médullaires lentes sont dues au développement dans le canal médullaire d’une lésion expansive. C’est une pathologie très fréquente dont le diagnostic est essentiellement clinique. L’imagerie par résonnance magnétique occupe une place incontournable dans le diagnostic de localisation et la recherche étiologique. En Europe l’étiologie tumorale est prépondérante. Le but de cette étude était de décrire les aspects IRM des compressions médullaires lentes et de déterminer le profil étiologique. Il s’agit d’une étude rétrospective portant sur 97 observations colligées au service de radiologie du CHUN de Fann sur une période de 30 mois (du 08/03/10 au 29/09/12). On été inclus dans l’étude, tous les patients adressés pour un tableau de compression médullaire lente survenu dans un contexte non traumatique. L’âge moyen des patients était de 42,6 ans avec des extrêmes compris entre 04 mois et 85 ans. Nous avons étudié la topographie des lésions (étage rachidien, compartiments canalaires) leur rehaussement et les critères d’orientation étiologique. Le protocole d’examen permettait la réalisation de séquence pondérées T1 sans avec injection de gado, T2, STIR et T2 DRIVE centrées sur les niveaux lésionnels ou les zones suspectes. L’IRM a permis de préciser le siège exact et l’étendue des lésions. L’atteinte du rachis dorsal représentait 42% des cas, suivi du rachis cervical avec 32% des cas. Les atteintes lombo-sacrées et pluri-étagées représentaient respectivement 18% et 08% des cas. Les lésions extradurales représentaient 87% des cas, suivi des lésions intradurales extramédullaires avec 08% des cas et des lésions intramédullaires dans 05% des cas. La particularité du profil étiologique de notre étude est la prédominance des épidurites infectieuses et la fréquence relative des épidurites métastatiques comparée aux séries occidentales. L’IRM vertébro-médullaire occupe

Measurement of the [Formula: see text] meson lifetime using [Formula: see text] decays.

Science.gov (United States)

Aaij, R; Adeva, B; Adinolfi, M; Affolder, A; Ajaltouni, Z; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Cartelle, P Alvarez; Alves, A A; Amato, S; Amerio, S; Amhis, Y; Anderlini, L; Anderson, J; Andreassen, R; Andreotti, M; Andrews, J E; Appleby, R B; Gutierrez, O Aquines; Archilli, F; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Bachmann, S; Back, J J; Badalov, A; Balagura, V; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Batozskaya, V; Bauer, Th; Bay, A; Beddow, J; Bedeschi, F; Bediaga, I; Belogurov, S; Belous, K; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Benton, J; Berezhnoy, A; Bernet, R; Bettler, M-O; van Beuzekom, M; Bien, A; Bifani, S; Bird, T; Bizzeti, A; Bjørnstad, P M; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Borsato, M; Bowcock, T J V; Bowen, E; Bozzi, C; Brambach, T; van den Brand, J; Bressieux, J; Brett, D; Britsch, M; Britton, T; Brook, N H; Brown, H; Bursche, A; Busetto, G; Buytaert, J; Cadeddu, S; Calabrese, R; Callot, O; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Campora Perez, D; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carranza-Mejia, H; Carson, L; Carvalho Akiba, K; Casse, G; Castillo Garcia, L; Cattaneo, M; Cauet, Ch; Cenci, R; Charles, M; Charpentier, Ph; Cheung, S-F; Chiapolini, N; Chrzaszcz, M; Ciba, K; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coca, C; Coco, V; Cogan, J; Cogneras, E; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coombes, M; Coquereau, S; Corti, G; Counts, I; Couturier, B; Cowan, G A; Craik, D C; Cruz Torres, M; Cunliffe, S; Currie, R; D'Ambrosio, C; Dalseno, J; David, P; David, P N Y; Davis, A; De Bonis, I; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Silva, W; De Simone, P; Decamp, D; Deckenhoff, M; Del Buono, L; Déléage, N; Derkach, D; Deschamps, O; Dettori, F; Di Canto, A; Dijkstra, H; Donleavy, S; Dordei, F; Dorigo, M; Dorosz, P; Dosil Suárez, A; Dossett, D; Dovbnya, A; Dupertuis, F; Durante, P; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; El Rifai, I; Elsasser, Ch; Falabella, A; Färber, C; Farinelli, C; Farry, S; Ferguson, D; Fernandez Albor, V; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fiore, M; Fiorini, M; Fitzpatrick, C; Fontana, M; Fontanelli, F; Forty, R; Francisco, O; Frank, M; Frei, C; Frosini, M; Furfaro, E; Gallas Torreira, A; Galli, D; Gandelman, M; Gandini, P; Gao, Y; Garofoli, J; Garra Tico, J; Garrido, L; Gaspar, C; Gauld, R; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gianelle, A; Gibson, V; Giubega, L; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gordon, H; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Griffith, P; Grillo, L; Grünberg, O; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Hafkenscheid, T W; Haines, S C; Hall, S; Hamilton, B; Hampson, T; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; Hartmann, T; He, J; Head, T; Heijne, V; Hennessy, K; Henrard, P; Hernando Morata, J A; van Herwijnen, E; Heß, M; Hicheur, A; Hill, D; Hoballah, M; Hombach, C; Hulsbergen, W; Hunt, P; Huse, T; Hussain, N; Hutchcroft, D; Hynds, D; Iakovenko, V; Idzik, M; Ilten, P; Jacobsson, R; Jaeger, A; Jans, E; Jaton, P; Jawahery, A; Jing, F; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Jurik, N; Kaballo, M; Kandybei, S; Kanso, W; Karacson, M; Karbach, T M; Kenyon, I R; Ketel, T; Khanji, B; Khurewathanakul, C; Klaver, S; Kochebina, O; Komarov, I; Koopman, R F; Koppenburg, P; Korolev, M; Kozlinskiy, A; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kucharczyk, M; Kudryavtsev, V; Kurek, K; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanciotti, E; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J-P; Lefèvre, R; Leflat, A; Lefrançois, J; Leo, S; Leroy, O; Lesiak, T; Leverington, B; Li, Y; Liles, M; Lindner, R; Linn, C; Lionetto, F; Liu, B; Liu, G; Lohn, S; Longstaff, I; Lopes, J H; Lopez-March, N; Lowdon, P; Lu, H; Lucchesi, D; Luisier, J; Luo, H; Luppi, E; Lupton, O; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Malde, S; Manca, G; Mancinelli, G; Manzali, M; Maratas, J; Marconi, U; Marino, P; Märki, R; Marks, J; Martellotti, G; Martens, A; Martín Sánchez, A; Martinelli, M; Martinez Santos, D; Martins Tostes, D; Massafferri, A; Matev, R; Mathe, Z; Matteuzzi, C; Mazurov, A; McCann, M; McCarthy, J; McNab, A; McNulty, R; McSkelly, B; Meadows, B; Meier, F; Meissner, M; Merk, M; Milanes, D A; Minard, M-N; Molina Rodriguez, J; Monteil, S; Moran, D; Morandin, M; Morawski, P; Mordà, A; Morello, M J; Mountain, R; Mous, I; Muheim, F; Müller, K; Muresan, R; Muryn, B; Muster, B; Naik, P; Nakada, T; Nandakumar, R; Nasteva, I; Needham, M; 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The lifetime of the [Formula: see text] meson is measured using semileptonic decays having a [Formula: see text] meson and a muon in the final state. The data, corresponding to an integrated luminosity of [Formula: see text], are collected by the LHCb detector in [Formula: see text] collisions at a centre-of-mass energy of 8 TeV. The measured lifetime is [Formula: see text]where the first uncertainty is statistical and the second is systematic.

The Holy See.

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1987-03-01

Focus in this discussion of the Holy See is on geography, the people, history, government and institutions, foreign relations, and relations with the US and the Holy See. Vatican City occupies 0.439 square kilometers (109 acres). Some 1000 individuals live within the Vatican's walls, most of whom are Italian or Swiss by nationality. Vatican citizenship usually is accorded only to those who reside in Vatican City by reason of office or employment and, with certain restrictions, to their families. The Pope delegates the internal administration of Vatican City to the Pontifical Commission for the State of the Vatican City, headed by the Cardinal Secretary of State. The legal system is based on canon law or the laws of the city of Rome. On February 11, 1929, the Holy See and the Italian government signed 3 agreements regulating a dispute since 1871 about the Law of Guarantees, law which sought to assure the Pope's spiritual freedom, an income, and special status for the Vatican area. The agreements include: a treaty recognizing the independence and sovereignty of the Holy See and creating the State of the Vatican City; a concordat fixing the relations between the government and the church within Italy; and a financial convention providing the Holy See with compensation for its losses in 1870. The Pope, at this time John Paul II, exercises supreme legislative, executive, and judicial power over the Holy See and within the State of the Vatican City. The Pope rules the Holy See through the Roman Curia and Papal Civil Service, which staffs it. The Holy See, which carries on an active diplomacy of considerable scope and variety, is particularly active diplomatically in international organizations. The US maintained consular relations with the Papal States from 1797-1870 and diplomatic relations with the Pope in his capacity as head of the Papal States. These relations lapsed with the final loss of all papal territories in 1870. In 1984, the US and the Holy See announced the

Measurement of the [Formula: see text] and [Formula: see text] production cross sections in multilepton final states using 3.2 fb[Formula: see text] of [Formula: see text] collisions at [Formula: see text] = 13 TeV with the ATLAS detector.

Science.gov (United States)

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2017-01-01

A measurement of the [Formula: see text] and [Formula: see text] production cross sections in final states with either two same-charge muons, or three or four leptons (electrons or muons) is presented. The analysis uses a data sample of proton-proton collisions at [Formula: see text] TeV recorded with the ATLAS detector at the Large Hadron Collider in 2015, corresponding to a total integrated luminosity of 3.2 fb[Formula: see text]. The inclusive cross sections are extracted using likelihood fits to signal and control regions, resulting in [Formula: see text] pb and [Formula: see text] pb, in agreement with the Standard Model predictions.

Use of Isotope Ratio Mass Spectrometry (IRMS) Determination ((18)O/(16)O) to Assess the Local Origin of Fish and Asparagus in Western Switzerland.

Science.gov (United States)

Rossier, Joël S; Maury, Valérie; de Voogd, Blaise; Pfammatter, Elmar

2014-10-01

Here we present the use of isotope ratio mass spectrometry (IRMS) for the detection of mislabelling of food produced in Switzerland. The system is based on the analysis of the oxygen isotope distribution in water (δ(18)O). Depending on the location on the earth, lake or groundwater has a specific isotopic distribution, which can serve as a fingerprint in order to verify whether a product has grown by means of the corresponding water. This report presents specifically the IRMS technique and the results obtained in the origin detection of fish grown in selected Swiss lakes as well as asparagus grown in Valais ground. Strengths and limitations of the method are presented for both cited products; on one hand, the technique is relatively universal for any product which contains significant water but on the other hand, it necessitates a rather heavy workload to build up a database of water δ(18)O values of products of different origins. This analytical tool is part of the concept of combating fraud currently in use in Switzerland.

Isotope Ratio Monitoring Gas Chromatography Mass Spectrometry (IRM-GCMS)

International Nuclear Information System (INIS)

Freeman, K.H.; Ricci, S.A.; Studley, A.; Hayes, J.M.

1989-01-01

On Earth, the C-13 content of organic compounds is depleted by roughly 13 to 23 permil from atmospheric carbon dioxide. This difference is largely due to isotope effects associated with the fixation of inorganic carbon by photosynthetic organisms. If life once existed on Mars, then it is reasonable to expect to observe a similar fractionation. Although the strongly oxidizing conditions on the surface of Mars make preservation of ancient organic material unlikely, carbon-isotope evidence for the existence of life on Mars may still be preserved. Carbon depleted in C-13 could be preserved either in organic compounds within buried sediments, or in carbonate minerals produced by the oxidation of organic material. A technique is introduced for rapid and precise measurement of the C-13 contents of individual organic compounds. A gas chromatograph is coupled to an isotope-ratio mass spectrometer through a combustion interface, enabling on-line isotopic analysis of isolated compounds. The isotope ratios are determined by integration of ion currents over the course of each chromatographic peak. Software incorporates automatic peak determination, corrections for background, and deconvolution of overlapped peaks. Overall performance of the instrument was evaluated by the analysis of a mixture of high purity n-alkanes of know isotopic composition. Isotopic values measured via IRM-GCMS averaged withing 0.55 permil of their conventionally measured values

Experiência do irmão sadio em relação à doença e hospitalização do irmão com câncer Experiencia del hermano saludable en relación a la enfermedad y hospitalización del hermano concáncer Experience of a healthy brother in relation to the disease and hospitalization of his brother with cancer

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Maria de Fátima de Lima Cheron

2011-01-01

Full Text Available OBJETIVO: Compreender o significado da experiência de ter um irmão com câncer na perspectiva do irmão sadio. MÉTODOS: Pesquisa descritiva de abordagem qualitativa. Foram realizadas entrevistas semiestruturadas com cinco irmãos de crianças com câncer assistidas em instituição filantrópica localizada no Município de São Paulo. RESULTADOS: O tema central tornando-se amadurecido com o sofrimento permitiu revelar que o irmão sadio torna-se amadurecido em razão do sofrimento que lhe é imposto no decorrer dos acontecimentos. Passa a valorizar a convivência familiar e os pequenos atos do cotidiano que lhe eram despercebidos. CONCLUSÃO: A equipe de saúde precisa reconhecer a experiência do irmão e incluí-lo no cuidado prestado em todas as fases da doença.OBJETIVO: Comprender el significado de la experiencia de tener un hermano con cáncer en la perspectiva del hermano saludable. MÉTODOS: Investigación descriptiva de abordaje cualitativo. Fueron realizadas entrevistas semiestructuradas con cinco hermanos de niños con cáncer asistidos en una institución filantrópica localizada en el Municipio de Sao Paulo. RESULTADOS: El tema central tornándose maduro con el sufrimiento permitió revelar que el hermano saludable madura en razón del sufrimiento que le es impuesto en el transcurso de los acontecimientos. Pasa a valorizar la convivencia familiar y los pequeños actos del cotidiano que le eran desapercibidos. CONCLUSIÓN: El equipo de salud necesita reconocer la experiencia del hermano e incluirlo en el cuidado prestado en todas las fases de la enfermedad.OBJECTIVE: To understand the meaning of the experience of having a sibling with cancer from the perspective of healthy brother. METHODS: A descriptive qualitative research approach. Semi-structured interviews were conducted with five siblings of children with cancer who were receiving care in a philanthropic institution located in São Paulo. RESULTS: The central theme that

A new derivatization method for δ18O analysis of individual carbohydrates with GC-Pyrolysis-IRMS

Science.gov (United States)

Lehmann, M. M.; Siegwolf, R. T.; Saurer, M.; Blees, J.; Fischer, M.; Zech, M.

2015-12-01

Compound specific isotope analysis (CSIA) with gas chromatography coupled to an isotope ratio mass spectrometer (GC-Pyr-IRMS) is nowadays a powerful tool that is widely used by a broad spectrum of research fields to investigate the isotopic signature of diverse metabolites. While many CSIA methods for carbon, hydrogen, and nitrogen isotopes are known, CSIA methods for the analysis of oxygen isotopes (δ18O) are still not widely established. Especially, reliable and precise methods for the δ18O analyses of individual carbohydrates are scarce, which is caused by the highly sensitive nature of the sugars. However, carbohydrates are important components of living organisms, source for many biochemical reactions, and can be found in all organisms, in soils, sediments, and in air. Thus, a method, allowing the investigation of the 18O/16O ratio in carbohydrates will enhance the scope of research using isotopes. We developed a new and easy to handle derivatization method to determine δ18O in carbohydrates with GC-Pyr-IRMS that consists of a catalyzed one-pot reaction in acetonitrile, resulting in complete methylation of all sugar hydroxyl groups within 24 hours, with silver oxide as the proton acceptor and methyl iodide as the methyl group carrier. Results derived from standard material show unrivalled δ18O precision ranging from about 0.2 to 1.1 ‰ for different individual carbohydrates of different classes and a generally very good accuracy, with a narrow range of 0.2 ‰ around the reference value, despite of high area variations. We applied this method on real samples, demonstrating that the method can commonly be used for analyzing honey samples, and for the analyses of more complex carbohydrate mixtures from plant leaves, including glucose, fructose, pinitol, and sucrose. Our new method may be used for food, beverage, and medical applications, as well as for biogeochemical and paleoclimatic sciences.

Profiling of new psychoactive substances (NPS) by using stable isotope ratio mass spectrometry (IRMS): study on the synthetic cannabinoid 5F-PB-22.

Science.gov (United States)

Münster-Müller, S; Scheid, N; Holdermann, T; Schneiders, S; Pütz, M

2018-05-21

In this paper results of a pilot study on the profiling of the synthetic cannabinoid receptor agonist 5F-PB-22 (5F-QUPIC, pentylfluoro-1H-indole-3-carboxylic acid-8-quinolinyl ester) via isotope ratio mass spectrometry are presented. It is focused on δ 13 C, δ 15 N and δ 2 H isotope ratios, which are determined using elemental analyser (EA) and high temperature elemental analyser (TC/EA) coupled to an isotope ratio mass spectrometer (IRMS). By means of a sample of pure material of 5F-PB-22 it is shown that the extraction of 5F-PB-22 from herbal material, a rapid clean-up procedure, or preparative column chromatography had no influences on the isotope ratios. Furthermore, 5F-PB-22 was extracted from fourteen different herbal blend samples ("Spice products" from police seizures) and analysed via IRMS, yielding three clusters containing seven, five and two samples, distinguishable through their isotopic composition, respectively. It is assumed that herbal blends in each cluster have been manufactured from individual batches of 5F-PB-22. This article is protected by copyright. All rights reserved.

Isotope ratio mass spectrometry (IRMS) versus laser-assisted ratio analyzer (LARA): a comparative study using two doses of.

Science.gov (United States)

Savarino, V; Landi, F; Dulbecco, P; Ricci, C; Tessieri, L; Biagini, R; Gatta, L; Miglioli, M; Celle, G; Vaira, D

2000-11-01

This study was carried out to compare the measurements and the diagnostic accuracy of the traditional expensive IRMS and the new economical LARA system using two doses of [13C]urea + two different test meals in patients undergoing upper gastrointestinal endoscopy, both before and after anti-Helicobacter treatment. A total of 354 dyspeptic patients underwent endoscopy with gastric biopsies to diagnose H. pylori infection by CLO-test and histology. No patients had taken antibiotics, bismuth, or antisecretory drugs in the 4 weeks before testing. After overnight fasting, breath samples were collected simultaneously in both plastic and glass tubes at baseline and at 30 and 60 min after urea ingestion. In 237 patients 100 mg [13C]urea + Ensure and in 117 patients 75 mg [13C]urea + citric acid were given. The test was also performed with the two urea dosages and meals in 67 and 64 infected patients, respectively, four weeks after anti-Helicobacter therapy. H. pylori was considered eradicated when both biopsy-based tests were negative. A delta value >5 per thousand was considered positive. Breath samples with insufficient CO2 levels at both 30 and 60 min were excluded from final analysis (N = 37 in pre- and N = 8 in posttreatment). There was excellent agreement between overall delta values of the two machines with both [13C]urea 100 mg + Ensure and [13C]urea 75 mg + citric acid. The 95% CI of the difference against the mean was wider with the former (mean -1.3, +6.3, and -9.4) than with the latter urea dosage and test meal (mean -1.2, +5.2 and -8.1). LARA and IRMS were equally effective (P = NS) in distinguishing infected from uninfected patients before therapy using both doses of [13C]urea and test meals (sensitivity ranged from 95% to 99% and specificity from 95% to 97%). This good performance was maintained in the posttreatment phase (sensitivity ranged from 90% to 100% and specificity from 90% to 97%), without any statistical difference among the various combinations

Measurement of CO{sub 2} and N{sub 2}O at nanomolar amounts using continuous-flow isotope-ratio mass spectrometry (CF-IRMS)

Energy Technology Data Exchange (ETDEWEB)

Patel, A; Downie, S.; Webster, E.; Hopkins, D.W.; Rennie, M.J. [Univ. of Dundee (United Kingdom)

1994-12-01

We are currently developing methods using Continuous Flow Isotope Ratio Mass Spectrometry (CF-IRMS) in conjunction with a thermal desorption purification unit to measure nanomolar levels of C0{sub 2} and N{sub 2}0. Samples of the pure gases diluted in He/air and transferred to septum capped Exetainers (Labco) provided a simple means to investigate the technique. We analyzed C0{sub 2} at natural abundance in the concentration range 50 to 5 nmoles and N{sub 2}0 at two concentrations between 25 and 5 nmoles. The technique was then used to measure C0{sub 2} (natural abundance and {sup 13}C-labeled) generated from the ninhydrin reaction. The results are summarized in a table; values are expressed in delta {sup 13}C notation relative to Pee Dee Belemnite. The data show that, provided care is taken to minimize or eliminate sources of contamination (air leaks, etc.), CF-IRMS coupled with a thermal desorption unit permits measurement of {sup 13}C enrichment in much smaller amounts of isolated amino acids than has been possible until now. The new methodology, including thermal desorption, should allow stable-isotope investigations on much smaller samples than are possible with other currently available techniques-while maintaining high precision.

[Symbol: see text]2 Optimized predictive image coding with [Symbol: see text]∞ bound.

Science.gov (United States)

Chuah, Sceuchin; Dumitrescu, Sorina; Wu, Xiaolin

2013-12-01

In many scientific, medical, and defense applications of image/video compression, an [Symbol: see text]∞ error bound is required. However, pure[Symbol: see text]∞-optimized image coding, colloquially known as near-lossless image coding, is prone to structured errors such as contours and speckles if the bit rate is not sufficiently high; moreover, most of the previous [Symbol: see text]∞-based image coding methods suffer from poor rate control. In contrast, the [Symbol: see text]2 error metric aims for average fidelity and hence preserves the subtlety of smooth waveforms better than the ∞ error metric and it offers fine granularity in rate control, but pure [Symbol: see text]2-based image coding methods (e.g., JPEG 2000) cannot bound individual errors as the [Symbol: see text]∞-based methods can. This paper presents a new compression approach to retain the benefits and circumvent the pitfalls of the two error metrics. A common approach of near-lossless image coding is to embed into a DPCM prediction loop a uniform scalar quantizer of residual errors. The said uniform scalar quantizer is replaced, in the proposed new approach, by a set of context-based [Symbol: see text]2-optimized quantizers. The optimization criterion is to minimize a weighted sum of the [Symbol: see text]2 distortion and the entropy while maintaining a strict [Symbol: see text]∞ error bound. The resulting method obtains good rate-distortion performance in both [Symbol: see text]2 and [Symbol: see text]∞ metrics and also increases the rate granularity. Compared with JPEG 2000, the new method not only guarantees lower [Symbol: see text]∞ error for all bit rates, but also it achieves higher PSNR for relatively high bit rates.

Compound-specific chlorine isotope ratios of TCE, PCE and DCE isomers by direct injection using CF-IRMS

International Nuclear Information System (INIS)

Shouakar-Stash, Orfan; Drimmie, Robert J.; Zhang Min; Frape, Shaun K.

2006-01-01

A method for determining compound-specific Cl isotopic compositions (δ 37 Cl) was developed for tetrachloroethene (PCE), trichloroethene (TCE), cis-dichloroethene (cis-DCE), trans-dichloroethene (trans-DCE) and 1,1-dichloroethene (1,1-DCE). The isotope ratio mass spectrometry (IRMS) used in this study has nine collectors, including two for m/z 50 and 52 (CH 3 Cl) and two for m/z 94 and 96 (CH 3 Br). The development of this method is based on the fact that fragments with mass ratios of 94/96, 95/97 and 96/98 are produced from PCE, TCE and DCE isomers during ion bombardment in the source of a mass spectrometer. Using continuous flow isotope ratio mass spectrometry coupled with gas chromatography (GC-CF-IRMS), it is possible to separate these compounds on-line and directly measure the Cl isotopic ratios of the fragments with the specific mass ratios. Both pure phase and aqueous samples were used for Cl isotopic analysis. For pure phase samples, a vapour phase of the chlorinated ethenes was injected directly into the GC, whereas the solid phase micro extraction (SPME) method was used to extract these compounds from aqueous solutions. The precisions of this analytical technique were ±0.12 per mille (1σ, n = 30), ±0.06 per mille (1σ, n = 30), and ±0.08 per mille (1σ, n = 15) for PCE, TCE and DCE isomers, respectively. The limits of quantification (LOQ) for analyzing Cl isotopic composition in aqueous solutions were 20, 5, and 5 μg/L for PCE, TCE and DCE isomers, respectively. This corresponds to 6-9 nano-mole of Cl, which is approximately 80 times lower than the most sensitive existing method. Compared to methods previously available, this new development offers the following advantages: (1) The much lower LOQ make it possible to extract these compounds directly from aqueous solutions using SPME without pre-concentration; (2) The linking of a GC with an IRMS eliminates off-line separation; and (3) Because the fragments used for isotopic ratio measurement are

Crianças que cuidam de irmãos com necessidades especiais

Directory of Open Access Journals (Sweden)

Moema P. G. Soares

Full Text Available Este estudo analisou situações em que um irmão/ã ajuda a cuidar de uma criança com necessidades especiais. Foram entrevistadas as mães e as crianças cuidadoras de 10 famílias de baixa renda, em Salvador-Bahia, com filhos portadores de paralisia cerebral. São detalhados os comportamentos de cuidado indicados pelas mães e pelas crianças cuidadoras, a participação das crianças em tarefas domésticas e suas atividades de lazer. Descrevem-se dificuldades e satisfação/insatisfação dos cuidadores com a tarefa, e expectativas de mães e crianças em relação ao futuro. Discute-se o grau de responsabilidade atribuído às crianças. Apontam-se limitações do estudo e algumas direções de intervenção para profissionais de saúde que atendem essas famílias.

{sup 2}H NMR and {sup 13}C-IRMS analyses of acetic acid from vinegar, {sup 18}O-IRMS analysis of water in vinegar: International collaborative study report

Energy Technology Data Exchange (ETDEWEB)

Thomas, Freddy [Eurofins Scientific Analytics, BP42301, 44323 Nantes (France); Jamin, Eric [Eurofins Scientific Analytics, BP42301, 44323 Nantes (France)

2009-09-01

An international collaborative study of isotopic methods applied to control the authenticity of vinegar was organized in order to support the recognition of these procedures as official methods. The determination of the {sup 2}H/{sup 1}H ratio of the methyl site of acetic acid by SNIF-NMR (site-specific natural isotopic fractionation-nuclear magnetic resonance) and the determination of the {sup 13}C/{sup 12}C ratio, by IRMS (isotope ratio mass spectrometry) provide complementary information to characterize the botanical origin of acetic acid and to detect adulterations of vinegar using synthetic acetic acid. Both methods use the same initial steps to recover pure acetic acid from vinegar. In the case of wine vinegar, the determination of the {sup 18}O/{sup 16}O ratio of water by IRMS allows to differentiate wine vinegar from vinegars made from dried grapes. The same set of vinegar samples was used to validate these three determinations. The precision parameters of the method for measuring {delta}{sup 13}C (carbon isotopic deviation) were found to be similar to the values previously obtained for similar methods applied to wine ethanol or sugars extracted from fruit juices: the average repeatability (r) was 0.45 per mille , and the average reproducibility (R) was 0.91 per mille . As expected from previous in-house study of the uncertainties, the precision parameters of the method for measuring the {sup 2}H/{sup 1}H ratio of the methyl site were found to be slightly higher than the values previously obtained for similar methods applied to wine ethanol or fermentation ethanol in fruit juices: the average repeatability was 1.34 ppm, and the average reproducibility was 1.62 ppm. This precision is still significantly smaller than the differences between various acetic acid sources ({delta}{sup 13}C and {delta}{sup 18}O) and allows a satisfactory discrimination of vinegar types. The precision parameters of the method for measuring {delta}{sup 18}O were found to be similar

Prevalence of Endoparasites in Faecal Samples of Cracids Bred in Captivity at the Parque Dois Irmãos, Recife, Pernambuco, Brazil

Directory of Open Access Journals (Sweden)

A. L. B. Cunha

2008-01-01

Full Text Available Among the many problems arising from poor sanitation that can affect wild birds maintained in captivity, parasitic afflictions are among the most frequent, and their effects can range from subclinical infections to death. Some of the most common cases involve endoparasites, principally if the species under consideration exists at a high population density. This being so, the aim of the current work was to report on the prevalence of endoparasites in faecal samples from cracids (curassows and allies bred in captivity at the Parque Dois Irmãos, Recife, Pernambuco state in Brazil. To do this, faecal and sand samples were collected from the enclosures of birds of the family Cracidae belonging to the collection from the Parque Dois Irmãos, which originated from private collections from the Metropolitan Region and Forest Zone of the State of Pernambuco. Four lots of faecal and sand samples were collected over a 60-day period, giving a total of 84 faecal samples from 58 individuals of 21 species of cracids. The material collected was submitted for coproparasitological tests using the right method and spontaneous sedimentation. The results obtained were positive for Strongyloides sp., Ascaridia sp., Capillaria sp. and cysts of Entamoeba coli, as well as eggs belonging to the superfamily Strongyloidea.

The differential production cross section of the [Formula: see text](1020) meson in [Formula: see text] = 7 TeV [Formula: see text] collisions measured with the ATLAS detector.

Science.gov (United States)

Aad, G; Abajyan, T; Abbott, B; Abdallah, J; Abdel Khalek, S; Abdelalim, A A; Abdinov, O; Aben, R; Abi, B; Abolins, M; AbouZeid, O S; Abramowicz, H; Abreu, H; Acharya, B S; Adamczyk, L; Adams, D L; Addy, T N; Adelman, J; Adomeit, S; Adragna, P; Adye, T; Aefsky, S; Aguilar-Saavedra, J A; Agustoni, M; Aharrouche, M; Ahlen, S P; Ahles, F; Ahmad, A; Ahsan, M; Aielli, G; Åkesson, T P A; Akimoto, G; Akimov, A V; Alam, M S; Alam, M A; Albert, J; Albrand, S; Aleksa, M; Aleksandrov, I N; Alessandria, F; Alexa, C; Alexander, G; Alexandre, G; Alexopoulos, T; Alhroob, M; Aliev, M; Alimonti, G; Alison, J; Allbrooke, B M M; Allport, P P; Allwood-Spiers, S E; Almond, J; Aloisio, A; Alon, R; Alonso, A; Alonso, F; Altheimer, A; Alvarez Gonzalez, B; Alviggi, M G; Amako, K; Amelung, C; Ammosov, V V; Amor Dos Santos, S P; Amorim, A; Amram, N; Anastopoulos, C; Ancu, L S; Andari, N; Andeen, T; Anders, C F; Anders, G; Anderson, K J; Andreazza, A; Andrei, V; Andrieux, M-L; Anduaga, X S; Angelidakis, S; Anger, P; Angerami, A; Anghinolfi, F; Anisenkov, A; Anjos, N; Annovi, A; Antonaki, A; Antonelli, M; Antonov, A; Antos, J; Anulli, F; Aoki, M; Aoun, S; Aperio Bella, L; Apolle, R; Arabidze, G; Aracena, I; Arai, Y; Arce, A T H; Arfaoui, S; Arguin, J-F; Argyropoulos, S; Arik, E; Arik, M; Armbruster, A J; Arnaez, O; Arnal, V; Arnault, C; Artamonov, A; Artoni, G; Arutinov, D; Asai, S; Ask, S; Åsman, B; Asquith, L; Assamagan, K; Astbury, A; Atkinson, M; Aubert, B; Auge, E; Augsten, K; Aurousseau, M; Avolio, G; Avramidou, R; Axen, D; Azuelos, G; Azuma, Y; Baak, M A; Baccaglioni, G; Bacci, C; Bach, A M; Bachacou, H; Bachas, K; Backes, M; Backhaus, M; Backus Mayes, J; Badescu, E; Bagnaia, P; Bahinipati, S; Bai, Y; Bailey, D C; Bain, T; Baines, J T; Baker, O K; Baker, M D; Baker, S; Balek, P; Banas, E; Banerjee, P; Banerjee, Sw; Banfi, D; Bangert, A; Bansal, V; Bansil, H S; Barak, L; Baranov, S P; Barbaro Galtieri, A; Barber, T; Barberio, E L; Barberis, D; Barbero, M; Bardin, D Y; Barillari, T; Barisonzi, M; Barklow, T; Barlow, N; Barnett, B M; Barnett, R M; Baroncelli, A; Barone, G; Barr, A J; Barreiro, F; Barreiro Guimarães da Costa, J; Barrillon, P; Bartoldus, R; Barton, A E; Bartsch, V; Basye, A; Bates, R L; Batkova, L; Batley, J R; Battaglia, A; Battistin, M; Bauer, F; Bawa, H S; Beale, S; Beau, T; Beauchemin, P H; Beccherle, R; Bechtle, P; Beck, H P; Becker, A K; Becker, S; Beckingham, M; Becks, K H; Beddall, A J; Beddall, A; Bedikian, S; Bednyakov, V A; Bee, C P; Beemster, L J; Begel, M; Behar Harpaz, S; Behera, P K; Beimforde, M; Belanger-Champagne, C; Bell, P J; Bell, W H; Bella, G; Bellagamba, L; Bellomo, M; Belloni, A; Beloborodova, O; Belotskiy, K; Beltramello, O; Benary, O; Benchekroun, D; Bendtz, K; Benekos, N; Benhammou, Y; Benhar Noccioli, E; Benitez Garcia, J A; Benjamin, D P; Benoit, M; Bensinger, J R; Benslama, K; Bentvelsen, S; Berge, D; Bergeaas Kuutmann, E; Berger, N; Berghaus, F; Berglund, E; Beringer, J; Bernat, P; Bernhard, R; Bernius, C; Berry, T; Bertella, C; Bertin, A; 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Chevalier, L; Chiefari, G; Chikovani, L; Childers, J T; Chilingarov, A; Chiodini, G; Chisholm, A S; Chislett, R T; Chitan, A; Chizhov, M V; Choudalakis, G; Chouridou, S; Christidi, I A; Christov, A; Chromek-Burckhart, D; Chu, M L; Chudoba, J; Ciapetti, G; Ciftci, A K; Ciftci, R; Cinca, D; Cindro, V; Ciocca, C; Ciocio, A; Cirilli, M; Cirkovic, P; Citron, Z H; Citterio, M; Ciubancan, M; Clark, A; Clark, P J; Clarke, R N; Cleland, W; Clemens, J C; Clement, B; Clement, C; Coadou, Y; Cobal, M; Coccaro, A; Cochran, J; Coffey, L; Cogan, J G; Coggeshall, J; Cogneras, E; Colas, J; Cole, S; Colijn, A P; Collins, N J; Collins-Tooth, C; Collot, J; Colombo, T; Colon, G; Compostella, G; Conde Muiño, P; Coniavitis, E; Conidi, M C; Consonni, S M; Consorti, V; Constantinescu, S; Conta, C; Conti, G; Conventi, F; Cooke, M; Cooper, B D; Cooper-Sarkar, A M; Copic, K; Cornelissen, T; Corradi, M; Corriveau, F; Cortes-Gonzalez, A; Cortiana, G; Costa, G; Costa, M J; Costanzo, D; Côté, D; Courneyea, L; Cowan, G; 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A measurement is presented of the [Formula: see text] production cross section at [Formula: see text] = 7 TeV using [Formula: see text] collision data corresponding to an integrated luminosity of 383 [Formula: see text], collected with the ATLAS experiment at the LHC. Selection of [Formula: see text](1020) mesons is based on the identification of charged kaons by their energy loss in the pixel detector. The differential cross section is measured as a function of the transverse momentum, [Formula: see text], and rapidity, [Formula: see text], of the [Formula: see text](1020) meson in the fiducial region 500 [Formula: see text] 1200 MeV, [Formula: see text] 0.8, kaon [Formula: see text] 230 MeV and kaon momentum [Formula: see text] 800 MeV. The integrated [Formula: see text]-meson production cross section in this fiducial range is measured to be [Formula: see text] = 570 [Formula: see text] 8 (stat) [Formula: see text] 66 (syst) [Formula: see text] 20 (lumi) [Formula: see text].

Measurement of quarkonium production at forward rapidity in [Formula: see text] collisions at [Formula: see text]TeV.

Science.gov (United States)

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Kim, D J; Kim, J S; Kim, M; Kim, M; Kim, S; Kim, T; Kirsch, S; Kisel, I; Kiselev, S; Kisiel, A; Kiss, G; Klay, J L; Klein, J; Klein-Bösing, C; Kluge, A; Knichel, M L; Knospe, A G; Kobdaj, C; Köhler, M K; Kollegger, T; Kolojvari, A; Kondratiev, V; Kondratyeva, N; Konevskikh, A; Kovalenko, V; Kowalski, M; Kox, S; Koyithatta Meethaleveedu, G; Kral, J; Králik, I; Kramer, F; Kravčáková, A; Krelina, M; Kretz, M; Krivda, M; Krizek, F; Krus, M; Kryshen, E; Krzewicki, M; Kučera, V; Kucheriaev, Y; Kugathasan, T; Kuhn, C; Kuijer, P G; Kulakov, I; Kumar, J; Kurashvili, P; Kurepin, A; Kurepin, A B; Kuryakin, A; Kushpil, S; Kweon, M J; Kwon, Y; Ladron de Guevara, P; Lagana Fernandes, C; Lakomov, I; Langoy, R; Lara, C; Lardeux, A; Lattuca, A; La Pointe, S L; La Rocca, P; Lea, R; Lee, G R; Legrand, I; Lehnert, J; Lemmon, R C; Lenti, V; Leogrande, E; Leoncino, M; León Monzón, I; Lévai, P; Li, S; Lien, J; Lietava, R; Lindal, S; Lindenstruth, V; Lippmann, C; Lisa, M A; Ljunggren, H M; Lodato, D F; Loenne, P I; Loggins, V R; Loginov, V; Lohner, D; Loizides, C; Lopez, X; López Torres, E; Lu, X-G; Luettig, P; Lunardon, M; Luo, J; Luparello, G; Luzzi, C; Ma, R; Maevskaya, A; Mager, M; Mahapatra, D P; Maire, A; Majka, R D; Malaev, M; Maldonado Cervantes, I; Malinina, L; Mal'Kevich, D; Malzacher, P; Mamonov, A; Manceau, L; Manko, V; Manso, F; Manzari, V; Marchisone, M; Mareš, J; Margagliotti, G V; Margotti, A; Marín, A; Markert, C; Marquard, M; Martashvili, I; Martin, N A; Martinengo, P; Martínez, M I; Martínez García, G; Martin Blanco, J; Martynov, Y; Mas, A; Masciocchi, S; Masera, M; Masoni, A; Massacrier, L; Mastroserio, A; Matyja, A; Mayer, C; Mazer, J; Mazzoni, M A; Meddi, F; Menchaca-Rocha, A; Mercado Pérez, J; Meres, M; Miake, Y; Mikhaylov, K; Milano, L; Milosevic, J; Mischke, A; Mishra, A N; Miśkowiec, D; Mitu, C M; Mlynarz, J; Mohanty, B; Molnar, L; Montaño Zetina, L; Montes, E; Morando, M; Moreira De Godoy, D A; Moretto, S; Morreale, A; Morsch, A; Muccifora, V; Mudnic, E; Muhuri, S; Mukherjee, M; 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The inclusive production cross sections at forward rapidity of [Formula: see text], [Formula: see text], [Formula: see text](1S) and [Formula: see text](2S) are measured in [Formula: see text] collisions at [Formula: see text] with the ALICE detector at the LHC. The analysis is based on a data sample corresponding to an integrated luminosity of 1.35 pb[Formula: see text]. Quarkonia are reconstructed in the dimuon-decay channel and the signal yields are evaluated by fitting the [Formula: see text] invariant mass distributions. The differential production cross sections are measured as a function of the transverse momentum [Formula: see text] and rapidity [Formula: see text], over the ranges [Formula: see text] GeV/c for [Formula: see text], [Formula: see text] GeV/c for all other resonances and for [Formula: see text]. The measured cross sections integrated over [Formula: see text] and [Formula: see text], and assuming unpolarized quarkonia, are: [Formula: see text] [Formula: see text]b, [Formula: see text] [Formula: see text]b, [Formula: see text] nb and [Formula: see text] nb, where the first uncertainty is statistical and the second one is systematic. The results are compared to measurements performed by other LHC experiments and to theoretical models.

SEEING IS BELIEVING, AND BELIEVING IS SEEING

Science.gov (United States)

Dutrow, B. L.

2009-12-01

Geoscience disciplines are filled with visual displays of data. From the first cave drawings to remote imaging of our Planet, visual displays of information have been used to understand and interpret our discipline. As practitioners of the art, visuals comprise the core around which we write scholarly articles, teach our students and make every day decisions. The effectiveness of visual communication, however, varies greatly. For many visual displays, a significant amount of prior knowledge is needed to understand and interpret various representations. If this is missing, key components of communication fail. One common example is the use of animations to explain high density and typically complex data. Do animations effectively convey information, simply "wow an audience" or do they confuse the subject by using unfamiliar forms and representations? Prior knowledge impacts the information derived from visuals and when communicating with non-experts this factor is exacerbated. For example, in an advanced geology course fractures in a rock are viewed by petroleum engineers as conduits for fluid migration while geoscience students 'see' the minerals lining the fracture. In contrast, a lay audience might view these images as abstract art. Without specific and direct accompanying verbal or written communication such an image is viewed radically differently by disparate audiences. Experts and non-experts do not 'see' equivalent images. Each visual must be carefully constructed with it's communication task in mind. To enhance learning and communication at all levels by visual displays of data requires that we teach visual literacy as a portion of our curricula. As we move from one form of visual representation to another, our mental images are expanded as is our ability to see and interpret new visual forms thus promoting life-long learning. Visual literacy is key to communication in our visually rich discipline. What do you see?

The all seeing eye?

NARCIS (Netherlands)

Koenderink, Jan J.

2014-01-01

The All Seeing Eye? Did you know that you are probably a believer in the All Seeing Eye? The odds are that I’m right—why? Well, the bulk of mainstream vision literature blindly relies on the All Seeing Eye. It is written all over papers, albeit between the lines. Understandably so, for scientists

IRMS detection of testosterone manipulated with 13C labeled standards in human urine by removing the labeled 13C

International Nuclear Information System (INIS)

Wang, Jingzhu; Yang, Rui; Yang, Wenning; Liu, Xin; Xing, Yanyi; Xu, Youxuan

2014-01-01

Highlights: • 13 C labeled testosterone can be used to adjust the isotope ratio of testosterone. • The novel testosterone cannot be detected by the regular IRMS method in doping test. • A method was explored to remove the labeled 13 C. • The established method can be used to detect the manipulated testosterone. - Abstract: Isotope ratio mass spectrometry (IRMS) is applied to confirm testosterone (T) abuse by determining the carbon isotope ratios (δ 13 C value). However, 13 C labeled standards can be used to control the δ 13 C value and produce manipulated T which cannot be detected by the current method. A method was explored to remove the 13 C labeled atom at C-3 from the molecule of androsterone (Andro), the metabolite of T in urine, to produce the resultant (A-nor-5α-androstane-2,17-dione, ANAD). The difference in δ 13 C values between Andro and ANAD (Δδ 13 C Andro–ANAD , ‰) would change significantly in case manipulated T is abused. Twenty-one volunteers administered T manipulated with different 13 C labeled standards. The collected urine samples were analyzed with the established method, and the maximum value of Δδ 13 C Andro–ANAD post ingestion ranged from 3.0‰ to 8.8‰. Based on the population reference, the cut-off value of Δδ 13 C Andro–ANAD for positive result was suggested as 1.2‰. The developed method could be used to detect T manipulated with 3- 13 C labeled standards

RH Department Information Meeting

CERN Multimedia

HR Department

2010-01-01

Dear Colleagues, HR Department would like to invite you to an information meeting which will be held on Thursday 30 September 2010 at 9:30 am in the Main Auditorium (Building 500)* A welcome coffee will be available from 9:00 a.m. The presentation will cover the CERN Competency Model which consists of the technical and behavioral competencies that are intrinsic to our Organization and its application in the various HR processes. This presentation will be followed by a questions & answers session. We look forward to seeing you all on 30 September! Best regards, Anne-Sylvie Catherin Head, Human Resources Department *This meeting will be simultaneously retransmitted and thereafter available at the following address: http://webcast.cern.ch.

Measurement of the [Formula: see text] production cross-section in proton-proton collisions via the decay [Formula: see text].

Science.gov (United States)

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Dijkstra, H; Donleavy, S; Dordei, F; Dorigo, M; Dosil Suárez, A; Dossett, D; Dovbnya, A; Dreimanis, K; Dujany, G; Dupertuis, F; Durante, P; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; El Rifai, I; Elena, E; Elsasser, Ch; Ely, S; Esen, S; Evans, H-M; Evans, T; Falabella, A; Färber, C; Farinelli, C; Farley, N; Farry, S; Fay, R F; Ferguson, D; Fernandez Albor, V; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fiore, M; Fiorini, M; Firlej, M; Fitzpatrick, C; Fiutowski, T; Fol, P; Fontana, M; Fontanelli, F; Forty, R; Francisco, O; Frank, M; Frei, C; Frosini, M; Fu, J; Furfaro, E; Gallas Torreira, A; Galli, D; Gallorini, S; Gambetta, S; Gandelman, M; Gandini, P; Gao, Y; García Pardiñas, J; Garofoli, J; Garra Tico, J; Garrido, L; Gaspar, C; Gauld, R; Gavardi, L; Gavrilov, G; Geraci, A; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gianelle, A; Gianì, S; Gibson, V; Giubega, L; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gotti, C; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Griffith, P; Grillo, L; Grünberg, O; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hall, S; Hamilton, B; Hampson, T; Han, X; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; He, J; Head, T; Heijne, V; Hennessy, K; Henrard, P; Henry, L; Hernando Morata, J A; van Herwijnen, E; Heß, M; Hicheur, A; Hill, D; Hoballah, M; Hombach, C; Hulsbergen, W; Hunt, P; Hussain, N; Hutchcroft, D; Hynds, D; Idzik, M; Ilten, P; Jacobsson, R; Jaeger, A; Jalocha, J; Jans, E; Jaton, P; Jawahery, A; Jing, F; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Jurik, N; Kaballo, M; Kandybei, S; Kanso, W; Karacson, M; Karbach, T M; Karodia, S; Kelsey, M; Kenyon, I R; Ketel, T; Khanji, B; Khurewathanakul, C; Klaver, S; Klimaszewski, K; Kochebina, O; Kolpin, M; Komarov, I; Koopman, R F; Koppenburg, P; Korolev, M; Kozlinskiy, A; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kucewicz, W; Kucharczyk, M; Kudryavtsev, V; Kurek, K; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanfranchi, G; Langenbruch, C; Langhans, B; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J-P; Lefèvre, R; Leflat, A; Lefrançois, J; Leo, S; Leroy, O; Lesiak, T; Leverington, B; Li, Y; Likhomanenko, T; Liles, M; Lindner, R; Linn, C; Lionetto, F; Liu, B; Lohn, S; Longstaff, I; Lopes, J H; Lopez-March, N; Lowdon, P; Lucchesi, D; Luo, H; Lupato, A; Luppi, E; Lupton, O; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Malde, S; Malinin, A; Manca, G; Mancinelli, G; Mapelli, A; Maratas, J; Marchand, J F; Marconi, U; Marin Benito, C; Marino, P; Märki, R; Marks, J; Martellotti, G; Martens, A; Sánchez, A Martín; Martinelli, M; Martinez Santos, D; Martinez Vidal, F; Martins Tostes, D; Massafferri, A; Matev, R; Mathe, Z; Matteuzzi, C; 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The production of the [Formula: see text] state in proton-proton collisions is probed via its decay to the [Formula: see text] final state with the LHCb detector, in the rapidity range [Formula: see text] and in the meson transverse-momentum range [Formula: see text]. The cross-section for prompt production of [Formula: see text] mesons relative to the prompt [Formula: see text] cross-section is measured, for the first time, to be [Formula: see text] at a centre-of-mass energy [Formula: see text] using data corresponding to an integrated luminosity of 0.7 fb[Formula: see text], and [Formula: see text] at [Formula: see text] using 2.0 fb[Formula: see text]. The uncertainties quoted are, in order, statistical, systematic, and that on the ratio of branching fractions of the [Formula: see text] and [Formula: see text] decays to the [Formula: see text] final state. In addition, the inclusive branching fraction of [Formula: see text]-hadron decays into [Formula: see text] mesons is measured, for the first time, to be [Formula: see text], where the third uncertainty includes also the uncertainty on the [Formula: see text] inclusive branching fraction from [Formula: see text]-hadron decays. The difference between the [Formula: see text] and [Formula: see text] meson masses is determined to be [Formula: see text].

Forensic analysis of explosives using isotope ratio mass spectrometry (IRMS)--part 2: forensic inter-laboratory trial: bulk carbon and nitrogen stable isotopes in a range of chemical compounds (Australia and New Zealand).

Science.gov (United States)

Benson, Sarah J; Lennard, Christopher J; Maynard, Philip; Hill, David M; Andrew, Anita S; Neal, Ken; Stuart-Williams, Hilary; Hope, Janet; Walker, G Stewart; Roux, Claude

2010-01-01

Comparability of data over time and between laboratories is a key issue for consideration in the development of global databases, and more broadly for quality assurance in general. One mechanism that can be utilized for evaluating traceability is an inter-laboratory trial. This paper addresses an inter-laboratory trial conducted across a number of Australian and New Zealand isotope ratio mass spectrometry (IRMS) laboratories. The main objective of this trial was to determine whether IRMS laboratories in these countries would record comparable values for the distributed samples. Four carbon containing and four nitrogen containing compounds were distributed to seven laboratories in Australia and one in New Zealand. The laboratories were requested to analyze the samples using their standard procedures. The data from each laboratory was evaluated collectively using International Standard ISO 13528 (Statistical methods for use in proficiency testing by inter-laboratory comparisons). "Warning signals" were raised against one participant in this trial. "Action signals" requiring corrective action were raised against four participants. These participants reviewed the data and possible sources for the discrepancies. This inter-laboratory trial was successful in providing an initial snapshot of the potential for traceability between the participating laboratories. The statistical methods described in this article could be used as a model for others needing to evaluate stable isotope results derived from multiple laboratories, e.g., inter-laboratory trials/proficiency testing. Ongoing trials will be conducted to improve traceability across the Australian and New Zealand IRMS community.

Comparison of quantitative NMR and IRMS spectrometry for the authentication of "Polish Vodka".

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Ciepielowski, Grzegorz; Pacholczyk-Sienicka, Barbara; Frączek, Tomasz; Klajman, Kamila; Paneth, Piotr; Albrecht, Łukasz

2018-05-31

The production of "Polish Vodka" is restricted by law to the ethyl alcohol of agricultural origins obtained from rye, wheat, barley, oat, triticale and potatoes grown on the territory of the Republic of Poland. The current labeling system should guarantee that the spirit is authentic and of good quality but not all producers are honest. Unfortunately, the authentic "Polish Vodka" is the most often counterfeited by the addition of cheaper and more accessible maize spirits. These illegal practices significantly reduce costs of the spirit production. Therefore, the determination of the botanical origin of alcohol in Poland is highly relevant. The quantitative 2 H NMR and isotope ratio mass spectrometry (IRMS) were used to investigate the authenticity of 30 samples of Polish spirits. Several isotopic parameters were used to determine the botanical origin of 10 unknown samples. Both approaches lead to the same conclusions regarding the percentage of maize-derived ethanol addition. Applied techniques are a valuable tool in the fight against counterfeiting of products. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

A reliable compound-specific nitrogen isotope analysis of amino acids by GC-C-IRMS following derivatisation into N-pivaloyl-iso-propyl (NPIP)esters for high-resolution food webs estimation.

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Zhang, Zhongyi; Tian, Jing; Xiao, Hongwei; Zheng, Nengjian; Gao, Xiaofei; Zhu, Renguo; Xiao, Huayun

2016-10-15

The signatures of natural stable nitrogen isotopic composition (δ(15)N) of individual amino acid (AA) have been confirmed to be a potentially effective tool for elucidating nitrogen cycling and trophic position of various organisms in food webs. In the present study, a two-stage derivatisation approach of esterification followed by acylation was evaluated. The biological samples underwent acid hydrolysis and the released individual AA was derivatived into corresponding N-pivaloyl-isopropyl (NPIP) esters for nitrogen isotopic analysis in gas chromatography-combustion-isotope ratio mass spectrometry (GC-C-IRMS). Usually, 13 individual AA derivatives were separated with fine baseline resolution based on a nonpolar gas chromatography column (DB-5ms). The minimum sample amount required under the presented conditions is larger than 20ngN on column in order to accurately determine the δ(15)N values. The δ(15)N values determined by GC-C-IRMS with a precision of better than 1‰, were within 1‰ after empirical correction compared to the corresponding measured by element analysis (EA)-IRMS. Bland-Altman plot showed highly consistency of the δ(15)N values determined by the two measurement techniques. Cation-exchange chromatography was applied to remove interfering fraction from the extracts of plant and animal samples and without nitrogen isotope fractionation during the treatment procedure. Moreover, this approach was carried out to estimate the trophic level of various natural organisms in a natural lake environment. Results highly proved that the trophic level estimated via the presented AA method well reflected the actual food web structure in natural environments. Copyright © 2016 Elsevier B.V. All rights reserved.

Carbon-Isotopic Analysis of Individual Pigments by HPLC-Moving Wire-IRMS

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Sessions, A. L.; Keely, B. J.; Hayes, J. M.

2003-12-01

We have developed a method for directly analyzing the carbon isotope ratios of individual pigments, including chlorophyll (chl) and its derivatives, by coupling a high-performance liquid chromatograph (HPLC) to an isotope-ratio mass spectrometer (IRMS) via a novel `moving-wire' interface. Pigments were separated on a reversed-phase C18 column, using a binary gradient modified from Airs et al. (2001, J. Chrom. A 917, 167-177). The HPLC effluent was dried onto a continuously-spooling nickel wire, and the involatile sample residue was combusted to CO2 and transferred to the IRMS for isotopic analysis. Replicate analyses of a standard solution yield precision for delta13C of better than 0.2‰ for injections containing ~5 μ g of chl-a. A five-fold improvement in sensitivity should be attainable using capillary HPLC to further reduce solvent volumes. The biomarker potential of tetrapyrrole pigments, combined with the geochemical information recorded by isotopic compositions, makes this combination a potent tool for biogeochemical studies. As a demonstration, we analyzed chlorophyll degradation products in sediments from a lake and a salina. First, compounds derived from bacteriochlorophylls (bchl)-c and -d were extracted from sediment cores taken at Kirisjes Lake (Larsmann Hills, Antarctica). These pigments are products of green sulfur bacteria and indicate the presence of an anoxic photic zone. The δ 13C values of bchl-related compounds are near -25‰ . Using published fractionations for Chlorobium species to extrapolate, dissolved CO2 in Kirisjes Lake probably had a δ 13C value of -12 to -21‰ and was strongly influenced by the recycling of organic carbon, possibly including methane. Second, compounds derived from chl-a, bchl-c, and bchl-d were isolated from sediments taken below a living microbial mat in the hypersaline les Salines de la Trinital (South Catalonia, Spain). The sediments contain visible remnants of past microbial mats and pigment distributions

Psychology departments in medical schools: there's one in Canada, eh?

Science.gov (United States)

McIlwraith, Robert D

2014-12-01

Comments on the original article by Robiner et al. (see record 2014-07939-001) regarding psychologists in medical schools and academic medical center settings. Robiner et al. reported that their extensive review "revealed no independent departments of psychology in U.S. medical schools." The current authors note north of the border in Canada there is one department of psychology in a medical school. The Department of Clinical Health Psychology has been a department within the Faculty of Medicine of the University of Manitoba since 1995. (PsycINFO Database Record (c) 2014 APA, all rights reserved).

OpenSeesPy: Python library for the OpenSees finite element framework

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Zhu, Minjie; McKenna, Frank; Scott, Michael H.

2018-01-01

OpenSees, an open source finite element software framework, has been used broadly in the earthquake engineering community for simulating the seismic response of structural and geotechnical systems. The framework allows users to perform finite element analysis with a scripting language and for developers to create both serial and parallel finite element computer applications as interpreters. For the last 15 years, Tcl has been the primary scripting language to which the model building and analysis modules of OpenSees are linked. To provide users with different scripting language options, particularly Python, the OpenSees interpreter interface was refactored to provide multi-interpreter capabilities. This refactoring, resulting in the creation of OpenSeesPy as a Python module, is accomplished through an abstract interface for interpreter calls with concrete implementations for different scripting languages. Through this approach, users are able to develop applications that utilize the unique features of several scripting languages while taking advantage of advanced finite element analysis models and algorithms.

Detection of counterfeit antiviral drug Heptodin and classification of counterfeits using isotope amount ratio measurements by multicollector inductively coupled plasma mass spectrometry (MC-ICPMS) and isotope ratio mass spectrometry (IRMS).

Science.gov (United States)

Santamaria-Fernandez, Rebeca; Hearn, Ruth; Wolff, Jean-Claude

2009-06-01

Isotope ratio mass spectrometry (IRMS) and multicollector inductively coupled plasma mass spectrometry (MC-ICP-MS) are highly important techniques that can provide forensic evidence that otherwise would not be available. MC-ICP-MS has proved to be a very powerful tool for measuring high precision and accuracy isotope amount ratios. In this work, the potential of combining isotope amount ratio measurements performed by MC-ICP-MS and IRMS for the detection of counterfeit pharmaceutical tablets has been investigated. An extensive study for the antiviral drug Heptodin has been performed for several isotopic ratios combining MC-ICP-MS and an elemental analyser EA-IRMS for stable isotope amount ratio measurements. The study has been carried out for 139 batches of the antiviral drug and analyses have been performed for C, S, N and Mg isotope ratios. Authenticity ranges have been obtained for each isotopic system and combined to generate a unique multi-isotopic pattern only present in the genuine tablets. Counterfeit tablets have then been identified as those tablets with an isotopic fingerprint outside the genuine isotopic range. The combination of those two techniques has therefore great potential for pharmaceutical counterfeit detection. A much greater power of discrimination is obtained when at least three isotopic systems are combined. The data from these studies could be presented as evidence in court and therefore methods need to be validated to support their credibility. It is also crucial to be able to produce uncertainty values associated to the isotope amount ratio measurements so that significant differences can be identified and the genuineness of a sample can be assessed.

Search for an additional, heavy Higgs boson in the [Formula: see text] decay channel at [Formula: see text] in [Formula: see text] collision data with the ATLAS detector.

Science.gov (United States)

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Zibell, A; Zieminska, D; Zimine, N I; Zimmermann, C; Zimmermann, S; Zinonos, Z; Zinser, M; Ziolkowski, M; Živković, L; Zobernig, G; Zoccoli, A; Zur Nedden, M; Zurzolo, G; Zwalinski, L

A search is presented for a high-mass Higgs boson in the [Formula: see text], [Formula: see text], [Formula: see text], and [Formula: see text] decay modes using the ATLAS detector at the CERN Large Hadron Collider. The search uses proton-proton collision data at a centre-of-mass energy of 8 TeV corresponding to an integrated luminosity of 20.3 fb[Formula: see text]. The results of the search are interpreted in the scenario of a heavy Higgs boson with a width that is small compared with the experimental mass resolution. The Higgs boson mass range considered extends up to [Formula: see text] for all four decay modes and down to as low as 140 [Formula: see text], depending on the decay mode. No significant excess of events over the Standard Model prediction is found. A simultaneous fit to the four decay modes yields upper limits on the production cross-section of a heavy Higgs boson times the branching ratio to [Formula: see text] boson pairs. 95 % confidence level upper limits range from 0.53 pb at [Formula: see text] GeV to 0.008 pb at [Formula: see text] GeV for the gluon-fusion production mode and from 0.31 pb at [Formula: see text] GeV to 0.009 pb at [Formula: see text] GeV for the vector-boson-fusion production mode. The results are also interpreted in the context of Type-I and Type-II two-Higgs-doublet models.

Working in the Finance and Procurement Department

CERN Multimedia

Laëtitia Pedroso

2010-01-01

The CERN Finance and Procurement (FP) Department handles around 35,000 internal purchase orders every year. A large number of them are processed by administrative assistant Sarah Pamelard and her two colleagues Dominique Trolliet and Laurence Fol. As you will see, this is not just any old desk job.   Sarah Pamelard in her office. Sarah Pamelard has worked at CERN for 23 years (see box). She began her career as an assistant in the electronics design office and has been an administrative assistant in the FP Department's purchasing service for the last year and a half. Her work involves processing all internal purchase orders for amounts not exceeding 10,000 CHF. "For each order we have to find the supplier who will provide the best services. Our search covers suppliers in all the Member States to ensure the best possible balance of financial return among them", explains Sarah. The skills that the job demands are not confined to the area of finance. Above all, you need to be very w...

7 CFR 868.261 - Grade and grade requirements for the classes of brown rice for processing. (See also § 868.263.)

Science.gov (United States)

2010-01-01

... Department of Agriculture (Continued) GRAIN INSPECTION, PACKERS AND STOCKYARD ADMINISTRATION (FEDERAL GRAIN INSPECTION SERVICE), DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS AND STANDARDS FOR CERTAIN AGRICULTURAL..., see § 868.263(c). 3 Plates should be used for southern production rice and sieves should be used for...

An automated GC-C-GC-IRMS setup to measure palaeoatmospheric δ13C-CH4, δ15N-N2O and δ18O-N2O in one ice core sample

Directory of Open Access Journals (Sweden)

P. Sperlich

2013-08-01

Full Text Available Air bubbles in ice core samples represent the only opportunity to study the mixing ratio and isotopic variability of palaeoatmospheric CH4 and N2O. The highest possible precision in isotope measurements is required to maximize the resolving power for CH4 and N2O sink and source reconstructions. We present a new setup to measure δ13C-CH4, δ15N-N2O and δ18O-N2O isotope ratios in one ice core sample and with one single IRMS instrument, with a precision of 0.09, 0.6 and 0.7‰, respectively, as determined on 0.6–1.6 nmol CH4 and 0.25–0.6 nmol N2O. The isotope ratios are referenced to the VPDB scale (δ13C-CH4, the N2-air scale (δ15N-N2O and the VSMOW scale (δ18O-N2O. Ice core samples of 200–500 g are melted while the air is constantly extracted to minimize gas dissolution. A helium carrier gas flow transports the sample through the analytical system. We introduce a new gold catalyst to oxidize CO to CO2 in the air sample. CH4 and N2O are then separated from N2, O2, Ar and CO2 before they get pre-concentrated and separated by gas chromatography. A combustion unit is required for δ13C-CH4 analysis, which is equipped with a constant oxygen supply as well as a post-combustion trap and a post-combustion GC column (GC-C-GC-IRMS. The post-combustion trap and the second GC column in the GC-C-GC-IRMS combination prevent Kr and N2O interferences during the isotopic analysis of CH4-derived CO2. These steps increase the time for δ13C-CH4 measurements, which is used to measure δ15N-N2O and δ18O-N2O first and then δ13C-CH4. The analytical time is adjusted to ensure stable conditions in the ion source before each sample gas enters the IRMS, thereby improving the precision achieved for measurements of CH4 and N2O on the same IRMS. The precision of our measurements is comparable to or better than that of recently published systems. Our setup is calibrated by analysing multiple reference gases that were injected over bubble-free ice samples. We show

Measurement of the isotope ratio of acetic acid in vinegar by HS-SPME-GC-TC/C-IRMS.

Science.gov (United States)

Hattori, Ryota; Yamada, Keita; Shibata, Hiroki; Hirano, Satoshi; Tajima, Osamu; Yoshida, Naohiro

2010-06-23

Acetic acid is the main ingredient of vinegar, and the worth of vinegar often depends on the fermentation of raw materials. In this study, we have developed a simple and rapid method for discriminating the fermentation of the raw materials of vinegar by measuring the hydrogen and carbon isotope ratio of acetic acid using head space solid-phase microextraction (HS-SPME) combined with gas chromatography-high temperature conversion or combustion-isotope ratio mass spectrometry (GC-TC/C-IRMS). The measurement of acetic acid in vinegar by this method was possible with repeatabilities (1sigma) of +/-5.0 per thousand for hydrogen and +/-0.4 per thousand for carbon, which are sufficient to discriminate the origin of acetic acid. The fermentation of raw materials of several vinegars was evaluated by this method.

Zygomycetes from herbivore dung in the ecological reserve of Dois Irmãos, Northeast Brazil

Directory of Open Access Journals (Sweden)

André Luiz Cabral Monteiro de Azevedo Santiago

2011-03-01

Full Text Available Thirty-eight taxa of Zygomycetes distributed in 15 genera were recorded from tapir (Tapirus terrestris, camel (Camelus bactrianus, horse (Equus caballus, deer (Cervus elaphus, agouti (Dasyprocta aguti, donkey (Equus asinus, llama (Llama glama and waterbuck (Kobus ellipsiprymnus dung collected at the Reserva Ecológica de Dois Irmãos located in Recife, State of Pernambuco, Northeast Brazil. The samples were collected on a monthly basis from June 2005 to May 2006, taken to the laboratory and incubated in moist chambers. Higher number of taxa was observed in the excrements of tapir, followed by deer and donkey. The highest number of species was detected for Mucor, followed by Pilobolus. Statistical analyses showed significant differences in richness of Zygomycetes taxa between the herbivore dung types. Differences of species composition, however, were weak. Seasonality influenced the Zygomycetes species composition but not its richness. Variations in taxa composition between ruminants and non-ruminants dung were non significant.

Zygomycetes From Herbivore Dung in the Ecological Reserve of Dois IrmÃOs, Northeast Brazil

Science.gov (United States)

de Azevedo Santiago, André Luiz Cabral Monteiro; Botelho Trufem, Sandra Farto; Malosso, Elaine; dos Santos, Paulo Jorge Parreira; de Queiroz Cavalcanti, Maria Auxiliadora

2011-01-01

Thirty-eight taxa of Zygomycetes distributed in 15 genera were recorded from tapir (Tapirus terrestris), camel (Camelus bactrianus), horse (Equus caballus), deer (Cervus elaphus), agouti (Dasyprocta aguti), donkey (Equus asinus), llama (Llama glama) and waterbuck (Kobus ellipsiprymnus) dung collected at the Reserva Ecológica de Dois Irmãos located in Recife, State of Pernambuco, Northeast Brazil. The samples were collected on a monthly basis from June 2005 to May 2006, taken to the laboratory and incubated in moist chambers. Higher number of taxa was observed in the excrements of tapir, followed by deer and donkey. The highest number of species was detected for Mucor, followed by Pilobolus. Statistical analyses showed significant differences in richness of Zygomycetes taxa between the herbivore dung types. Differences of species composition, however, were weak. Seasonality influenced the Zygomycetes species composition but not its richness. Variations in taxa composition between ruminants and non-ruminants dung were non significant. PMID:24031609

HP-SEE User Forum 2012

CERN Document Server

Karaivanova, Aneta; Oulas, Anastasis; Liabotis, Ioannis; Stojiljkovic, Danica; Prnjat, Ognjen

2014-01-01

This book is a collection of carefully reviewed papers presented during the HP-SEE User Forum, the meeting of the High-Performance Computing Infrastructure for South East Europe’s (HP-SEE) Research Communities, held in October 17-19, 2012, in Belgrade, Serbia. HP-SEE aims at supporting and integrating regional HPC infrastructures; implementing solutions for HPC in the region; and making HPC resources available to research communities in SEE, region, which are working in a number of scientific fields with specific needs for massively parallel execution on powerful computing resources. HP-SEE brings together research communities and HPC operators from 14 different countries and enables them to share HPC facilities, software, tools, data and research results, thus fostering collaboration and strengthening the regional and national human network; the project specifically supports research groups in the areas of computational physics, computational chemistry and the life sciences. The contributions presented i...

Synthesis of 1-octacosanol and GC-C-IRMS discrimination of samples from different origin.

Science.gov (United States)

Cravotto, Giancarlo; Calcio Gaudino, Emanuela; Barge, Alessandro; Binello, Arianna; Albertino, Andrea; Aghemo, Costanza

2010-03-01

Lately, long-chain primary alcohols have been investigated in depth on account of their biological activities. In particular, 1-octacosanol (C(28)H(57)OH), the main component of policosanol, the hypolipidaemic fatty alcohol mixture obtained from sugar cane wax, has been the subject of a multitude of pharmacological studies. The aim of this work was to search a convenient synthetic protocol for the preparation of 1-octacosanol in a gram scale. The key step was a Wittig reaction between the octadecyltriphenylphosphonium ylide and the methyl 10-oxodecanoate. Some steps were further improved by power ultrasound and microwave irradiation, either alone or in combination. Our methodology is suitable for a rapid generation of homologues by varying the chain length in the alkyl halide. Due to the high commercial value, a series of 1-octacosanol samples, either isolated from natural sources or from synthesis (different origin and suppliers), were analysed by gas chromatography-combustion-isotopic ratio mass spectrometry (GC-C-IRMS) and according to the carbon isotopic content, classified on the basis of their origin.

Energy dependence of forward-rapidity [Formula: see text] and [Formula: see text] production in pp collisions at the LHC.

Science.gov (United States)

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Gonzalez, V; González-Zamora, P; Gorbunov, S; Görlich, L; Gotovac, S; Grabski, V; Graczykowski, L K; Graham, K L; Greiner, L; Grelli, A; Grigoras, C; Grigoriev, V; Grigoryan, A; Grigoryan, S; Grion, N; Gronefeld, J M; Grosa, F; Grosse-Oetringhaus, J F; Grosso, R; Gruber, L; Grull, F R; Guber, F; Guernane, R; Guerzoni, B; Gulbrandsen, K; Gunji, T; Gupta, A; Gupta, R; Guzman, I B; Haake, R; Hadjidakis, C; Hamagaki, H; Hamar, G; Hamon, J C; Harris, J W; Harton, A; Hatzifotiadou, D; Hayashi, S; Heckel, S T; Hellbär, E; Helstrup, H; Herghelegiu, A; Herrera Corral, G; Herrmann, F; Hess, B A; Hetland, K F; Hillemanns, H; Hippolyte, B; Hladky, J; Hohlweger, B; Horak, D; Hosokawa, R; Hristov, P; Hughes, C; Humanic, T J; Hussain, N; Hussain, T; Hutter, D; Hwang, D S; Ilkaev, R; Inaba, M; Ippolitov, M; Irfan, M; Isakov, V; Islam, M S; Ivanov, M; Ivanov, V; Izucheev, V; Jacak, B; Jacazio, N; Jacobs, P M; Jadhav, M B; Jadlovska, S; Jadlovsky, J; Jaelani, S; Jahnke, C; Jakubowska, M J; Janik, M A; Jayarathna, P H S Y; Jena, C; Jena, S; Jercic, M; Jimenez Bustamante, R T; Jones, P G; Jusko, A; Kalinak, P; Kalweit, A; Kang, J H; Kaplin, V; Kar, S; Karasu Uysal, A; Karavichev, O; Karavicheva, T; Karayan, L; Karpechev, E; Kebschull, U; Keidel, R; Keijdener, D L D; Keil, M; Ketzer, B; Mohisin Khan, M; Khan, P; Khan, S A; Khanzadeev, A; Kharlov, Y; Khatun, A; Khuntia, A; Kielbowicz, M M; Kileng, B; Kim, D; Kim, D W; Kim, D J; Kim, H; Kim, J S; Kim, J; Kim, M; Kim, M; Kim, S; Kim, T; Kirsch, S; Kisel, I; Kiselev, S; Kisiel, A; Kiss, G; Klay, J L; Klein, C; Klein, J; Klein-Bösing, C; Klewin, S; Kluge, A; Knichel, M L; Knospe, A G; Kobdaj, C; Kofarago, M; Kollegger, T; Kolojvari, A; Kondratiev, V; Kondratyeva, N; Kondratyuk, E; Konevskikh, A; Kopcik, M; Kour, M; Kouzinopoulos, C; Kovalenko, O; Kovalenko, V; Kowalski, M; Koyithatta Meethaleveedu, G; Králik, I; Kravčáková, A; Krivda, M; Krizek, F; Kryshen, E; Krzewicki, M; Kubera, A M; Kučera, V; Kuhn, C; Kuijer, P G; Kumar, A; Kumar, J; Kumar, L; Kumar, S; Kundu, S; Kurashvili, P; Kurepin, A; Kurepin, A B; Kuryakin, A; Kushpil, S; Kweon, M J; Kwon, Y; La Pointe, S L; La Rocca, P; Lagana Fernandes, C; Lakomov, I; Langoy, R; Lapidus, K; Lara, C; Lardeux, A; Lattuca, A; Laudi, E; Lavicka, R; Lazaridis, L; Lea, R; Leardini, L; Lee, S; Lehas, F; Lehner, S; Lehrbach, J; Lemmon, R C; Lenti, V; Leogrande, E; León Monzón, I; Lévai, P; Li, S; Li, X; Lien, J; Lietava, R; Lindal, S; Lindenstruth, V; Lippmann, C; Lisa, M A; Litichevskyi, V; Ljunggren, H M; Llope, W J; Lodato, D F; Loenne, P I; Loginov, V; Loizides, C; Loncar, P; Lopez, X; López Torres, E; Lowe, A; Luettig, P; Lunardon, M; Luparello, G; Lupi, M; Lutz, T H; Maevskaya, A; Mager, M; Mahajan, S; Mahmood, S M; Maire, A; Majka, R D; Malaev, M; Maldonado Cervantes, I; Malinina, L; Mal'Kevich, D; Malzacher, P; Mamonov, A; Manko, V; Manso, F; Manzari, V; Mao, Y; Marchisone, M; Mareš, J; Margagliotti, G V; Margotti, A; Margutti, J; Marín, A; Markert, C; Marquard, M; Martin, N A; Martinengo, P; Martinez, J A L; Martínez, M I; Martínez García, G; Martinez Pedreira, M; Mas, A; Masciocchi, S; Masera, M; Masoni, A; Mastroserio, A; Mathis, A M; Matyja, A; Mayer, C; Mazer, J; Mazzilli, M; Mazzoni, M A; Meddi, F; Melikyan, Y; Menchaca-Rocha, A; Meninno, E; Mercado Pérez, J; Meres, M; Mhlanga, S; Miake, Y; Mieskolainen, M M; Mihaylov, D L; Mikhaylov, K; Milano, L; Milosevic, J; Mischke, A; Mishra, A N; Miśkowiec, D; Mitra, J; Mitu, C M; Mohammadi, N; Mohanty, B; Montes, E; Moreira De Godoy, D A; Moreno, L A P; Moretto, S; Morreale, A; Morsch, A; Muccifora, V; Mudnic, E; Mühlheim, D; Muhuri, S; Mukherjee, M; Mulligan, J D; Munhoz, M G; Münning, K; Munzer, R H; Murakami, H; Murray, S; Musa, L; Musinsky, J; Myers, C J; Naik, B; Nair, R; Nandi, B K; Nania, R; Nappi, E; Naru, M U; Natal da Luz, H; Nattrass, C; Navarro, S R; Nayak, K; Nayak, R; Nayak, T K; Nazarenko, S; Nedosekin, A; Negrao De Oliveira, R A; Nellen, L; Nesbo, S V; Ng, F; Nicassio, M; Niculescu, M; Niedziela, J; Nielsen, B S; Nikolaev, S; Nikulin, S; Nikulin, V; Noferini, F; Nomokonov, P; Nooren, G; Noris, J C C; Norman, J; Nyanin, A; Nystrand, J; Oeschler, H; Oh, S; Ohlson, A; Okubo, T; Olah, L; Oleniacz, J; Oliveira Da Silva, A C; Oliver, M H; Onderwaater, J; Oppedisano, C; Orava, R; Oravec, M; Ortiz Velasquez, A; Oskarsson, A; Otwinowski, J; Oyama, K; Pachmayer, Y; Pacik, V; Pagano, D; Pagano, P; Paić, G; Palni, P; Pan, J; Pandey, A K; Panebianco, S; Papikyan, V; Pappalardo, G S; Pareek, P; Park, J; Park, W J; Parmar, S; Passfeld, A; Pathak, S P; Paticchio, V; Patra, R N; Paul, B; Pei, H; Peitzmann, T; Peng, X; Pereira, L G; Pereira Da Costa, H; Peresunko, D; Perez Lezama, E; Peskov, V; Pestov, Y; Petráček, V; Petrov, V; Petrovici, M; Petta, C; Pezzi, R P; Piano, S; Pikna, M; Pillot, P; Pimentel, L O D L; Pinazza, O; Pinsky, L; Piyarathna, D B; Płoskoń, M; Planinic, M; Pluta, J; Pochybova, S; Podesta-Lerma, P L M; Poghosyan, M G; Polichtchouk, B; Poljak, N; Poonsawat, W; Pop, A; Poppenborg, H; Porteboeuf-Houssais, S; Porter, J; Pospisil, J; Pozdniakov, V; Prasad, S K; Preghenella, R; Prino, F; Pruneau, C A; Pshenichnov, I; Puccio, M; Puddu, G; Pujahari, P; Punin, V; Putschke, J; Qvigstad, H; Rachevski, A; Raha, S; Rajput, S; Rak, J; Rakotozafindrabe, A; Ramello, L; Rami, F; Rana, D B; Raniwala, R; Raniwala, S; Räsänen, S S; Rascanu, B T; Rathee, D; Ratza, V; Ravasenga, I; Read, K F; Redlich, K; Rehman, A; Reichelt, P; Reidt, F; Ren, X; Renfordt, R; Reolon, A R; Reshetin, A; Reygers, K; Riabov, V; Ricci, R A; Richert, T; Richter, M; Riedler, P; Riegler, W; Riggi, F; Ristea, C; Rodríguez Cahuantzi, M; Røed, K; Rogochaya, E; Rohr, D; Röhrich, D; Rokita, P S; Ronchetti, F; Ronflette, L; Rosnet, P; Rossi, A; Rotondi, A; Roukoutakis, F; Roy, A; Roy, C; Roy, P; Rubio Montero, A J; Rueda, O V; Rui, R; Russo, R; Rustamov, A; Ryabinkin, E; Ryabov, Y; Rybicki, A; Saarinen, S; Sadhu, S; Sadovsky, S; Šafařík, K; Saha, S K; Sahlmuller, B; Sahoo, B; Sahoo, P; Sahoo, R; Sahoo, S; Sahu, P K; Saini, J; Sakai, S; Saleh, M A; Salzwedel, J; Sambyal, S; Samsonov, V; Sandoval, A; Sarkar, D; Sarkar, N; Sarma, P; Sas, M H P; Scapparone, E; Scarlassara, F; Scharenberg, R P; Scheid, H S; Schiaua, C; Schicker, R; Schmidt, C; Schmidt, H R; Schmidt, M O; Schmidt, M; Schuchmann, S; Schukraft, J; Schutz, Y; Schwarz, K; Schweda, K; Scioli, G; Scomparin, E; Scott, R; Šefčík, M; Seger, J E; Sekiguchi, Y; Sekihata, D; Selyuzhenkov, I; Senosi, K; Senyukov, S; Serradilla, E; Sett, P; Sevcenco, A; Shabanov, A; Shabetai, A; Shadura, O; Shahoyan, R; Shangaraev, A; Sharma, A; Sharma, A; Sharma, M; Sharma, M; Sharma, N; Sheikh, A I; Shigaki, K; Shou, Q; Shtejer, K; Sibiriak, Y; Siddhanta, S; Sielewicz, K M; Siemiarczuk, T; Silvermyr, D; Silvestre, C; Simatovic, G; Simonetti, G; Singaraju, R; Singh, R; Singhal, V; Sinha, T; Sitar, B; Sitta, M; Skaali, T B; Slupecki, M; Smirnov, N; Snellings, R J M; Snellman, T W; Song, J; Song, M; Soramel, F; Sorensen, S; Sozzi, F; Spiriti, E; Sputowska, I; Srivastava, B K; Stachel, J; Stan, I; Stankus, P; Stenlund, E; Stiller, J H; Stocco, D; Strmen, P; Suaide, A A P; Sugitate, T; Suire, C; Suleymanov, M; Suljic, M; Sultanov, R; Šumbera, M; Sumowidagdo, S; Suzuki, K; Swain, S; Szabo, A; Szarka, I; Szczepankiewicz, A; Szymanski, M; Tabassam, U; Takahashi, J; Tambave, G J; Tanaka, N; Tarhini, M; Tariq, M; Tarzila, M G; Tauro, A; Tejeda Muñoz, G; Telesca, A; Terasaki, K; Terrevoli, C; Teyssier, B; Thakur, D; Thakur, S; Thomas, D; Tieulent, R; Tikhonov, A; Timmins, A R; Toia, A; Tripathy, S; Trogolo, S; Trombetta, G; Trubnikov, V; Trzaska, W H; Trzeciak, B A; Tsuji, T; Tumkin, A; Turrisi, R; Tveter, T S; Ullaland, K; Umaka, E N; Uras, A; Usai, G L; Utrobicic, A; Vala, M; Van Der Maarel, J; Van Hoorne, J W; van Leeuwen, M; Vanat, T; Vande Vyvre, P; Varga, D; Vargas, A; Vargyas, M; Varma, R; Vasileiou, M; Vasiliev, A; Vauthier, A; Vázquez Doce, O; Vechernin, V; Veen, A M; Velure, A; Vercellin, E; Vergara Limón, S; Vernet, R; Vértesi, R; Vickovic, L; Vigolo, S; Viinikainen, J; Vilakazi, Z; Villalobos Baillie, O; Villatoro Tello, A; Vinogradov, A; Vinogradov, L; Virgili, T; Vislavicius, V; Vodopyanov, A; Völkl, M A; Voloshin, K; Voloshin, S A; Volpe, G; von Haller, B; Vorobyev, I; Voscek, D; Vranic, D; Vrláková, J; Wagner, B; Wagner, J; Wang, H; Wang, M; Watanabe, D; Watanabe, Y; Weber, M; Weber, S G; Weiser, D F; Wessels, J P; Westerhoff, U; Whitehead, A M; Wiechula, J; Wikne, J; Wilk, G; Wilkinson, J; Willems, G A; Williams, M C S; Windelband, B; Witt, W E; Yalcin, S; Yang, P; Yano, S; Yin, Z; Yokoyama, H; Yoo, I-K; Yoon, J H; Yurchenko, V; Zaccolo, V; Zaman, A; Zampolli, C; Zanoli, H J C; Zardoshti, N; Zarochentsev, A; Závada, P; Zaviyalov, N; Zbroszczyk, H; Zhalov, M; Zhang, H; Zhang, X; Zhang, Y; Zhang, C; Zhang, Z; Zhao, C; Zhigareva, N; Zhou, D; Zhou, Y; Zhou, Z; Zhu, H; Zhu, J; Zhu, X; Zichichi, A; Zimmermann, A; Zimmermann, M B; Zimmermann, S; Zinovjev, G; Zmeskal, J

2017-01-01

We present results on transverse momentum ([Formula: see text]) and rapidity ([Formula: see text]) differential production cross sections, mean transverse momentum and mean transverse momentum square of inclusive [Formula: see text] and [Formula: see text] at forward rapidity ([Formula: see text]) as well as [Formula: see text]-to-[Formula: see text] cross section ratios. These quantities are measured in pp collisions at center of mass energies [Formula: see text] and 13 TeV with the ALICE detector. Both charmonium states are reconstructed in the dimuon decay channel, using the muon spectrometer. A comprehensive comparison to inclusive charmonium cross sections measured at [Formula: see text], 7 and 8 TeV is performed. A comparison to non-relativistic quantum chromodynamics and fixed-order next-to-leading logarithm calculations, which describe prompt and non-prompt charmonium production respectively, is also presented. A good description of the data is obtained over the full [Formula: see text] range, provided that both contributions are summed. In particular, it is found that for [Formula: see text] GeV/ c the non-prompt contribution reaches up to 50% of the total charmonium yield.

IRMS detection of testosterone manipulated with {sup 13}C labeled standards in human urine by removing the labeled {sup 13}C

Energy Technology Data Exchange (ETDEWEB)

Wang, Jingzhu, E-mail: wangjingzhu@chinada.cn [National Anti-Doping Laboratory, China Anti-Doping Agency, Beijing (China); Yang, Rui [Sport Science College, Beijing Sport University Beijing, Beijing (China); Yang, Wenning [School of Pharmacy, Beijing University of Chinese Medicine, Beijing (China); Liu, Xin; Xing, Yanyi; Xu, Youxuan [National Anti-Doping Laboratory, China Anti-Doping Agency, Beijing (China)

2014-12-10

Highlights: • {sup 13}C labeled testosterone can be used to adjust the isotope ratio of testosterone. • The novel testosterone cannot be detected by the regular IRMS method in doping test. • A method was explored to remove the labeled {sup 13}C. • The established method can be used to detect the manipulated testosterone. - Abstract: Isotope ratio mass spectrometry (IRMS) is applied to confirm testosterone (T) abuse by determining the carbon isotope ratios (δ{sup 13}C value). However, {sup 13}C labeled standards can be used to control the δ{sup 13}C value and produce manipulated T which cannot be detected by the current method. A method was explored to remove the {sup 13}C labeled atom at C-3 from the molecule of androsterone (Andro), the metabolite of T in urine, to produce the resultant (A-nor-5α-androstane-2,17-dione, ANAD). The difference in δ{sup 13}C values between Andro and ANAD (Δδ{sup 13}C{sub Andro–ANAD}, ‰) would change significantly in case manipulated T is abused. Twenty-one volunteers administered T manipulated with different {sup 13}C labeled standards. The collected urine samples were analyzed with the established method, and the maximum value of Δδ{sup 13}C{sub Andro–ANAD} post ingestion ranged from 3.0‰ to 8.8‰. Based on the population reference, the cut-off value of Δδ{sup 13}C{sub Andro–ANAD} for positive result was suggested as 1.2‰. The developed method could be used to detect T manipulated with 3-{sup 13}C labeled standards.

Hearing Voices and Seeing Things

Science.gov (United States)

... Facts for Families Guide Facts for Families - Vietnamese Hearing Voices and Seeing Things No. 102; Updated October ... delusions (a fixed, false, and often bizarre belief). Hearing voices or seeing things that are not there ...

Isotope determination of sulfur by mass spectrometry in soil samples Determinação isotópica de enxofre por espectrometria de massas (irms em amostras de solo

Directory of Open Access Journals (Sweden)

Alexssandra Luiza Rodrigues Molina Rossete

2012-12-01

Full Text Available Sulphur plays an essential role in plants and is one of the main nutrients in several metabolic processes. It has four stable isotopes (32S, 33S, 34S, and 36S with a natural abundance of 95.00, 0.76, 4.22, and 0.014 in atom %, respectively. A method for isotopic determination of S by isotope-ratio mass spectrometry (IRMS in soil samples is proposed. The procedure involves the oxidation of organic S to sulphate (S-SO4(2-, which was determined by dry combustion with alkaline oxidizing agents. The total S-SO4(2- concentration was determined by turbidimetry and the results showed that the conversion process was adequate. To produce gaseous SO2 gas, BaSO4 was thermally decomposed in a vacuum system at 900 ºC in the presence of NaPO3. The isotope determination of S (atom % 34S atoms was carried out by isotope ratio mass spectrometry (IRMS. In this work, the labeled material (K2(34SO4 was used to validate the method of isotopic determination of S; the results were precise and accurate, showing the viability of the proposed method.O enxofre tem papel essencial em plantas, sendo um dos principais nutrientes em diversos processos metabólicos; ele apresenta quatro isótopos estáveis (32S, 33S, 34S e 36S, com abundância natural de 95,00, 0,76, 4,22 e 0,014 % em átomos, respectivamente. Desenvolver um método para determinação isotópica do S por espectrometria de massas de razão isotópica (IRMS em amostras de solo foi o objetivo deste trabalho. A oxidação de S orgânico a sulfato (S-SO4(2- foi avaliada utilizando a oxidação via seca com agentes oxidantes alcalinos. A concentração S-SO4(2- foi determinada pelo método turbidimétrico, e os resultados mostraram que o processo de conversão foi adequado. A obtenção do gás SO2 foi por decomposição térmica do BaSO4 em uma linha de vácuo a 900 ºC, em presença de NaPO3. A determinação isotópica do S (% em átomos de 34S foi realizada em um espectrômetro de massa (IRMS. Neste trabalho, a

A new system for the simultaneous measurement of δ{sup 13}C and δ{sup 15}N by IRMS and radiocarbon by AMS on gaseous samples: Design features and performances of the gas handling interface

Energy Technology Data Exchange (ETDEWEB)

Braione, Eugenia; Maruccio, Lucio; Quarta, Gianluca; D’Elia, Marisa; Calcagnile, Lucio, E-mail: lucio.calcagnile@unisalento.it

2015-10-15

We present the general design features and preliminary performances of a new system for the simultaneous AMS-{sup 14}C and IRMS δ{sup 13}C and δ{sup 15}N measurements on samples with masses in the μg range. The system consists of an elemental analyzer (EA), a gas splitting unit (GSU), a IRMS system, a gas handling interface (GHI) and a sputtering ion source capable of accepting gaseous samples. A detailed description of the system and of the control software supporting unattended operation are presented together with the first performance tests carried out by analyzing samples with masses ranging from 8 μgC to 2.4 mgC. The performances of the system were tested in term of stability of the ion beam extracted from the ion source, precision and accuracy of the results by comparing the measured isotopic ratios with those expected for reference materials.

29 CFR 1918.94 - Ventilation and atmospheric conditions (See also § 1918.2, definitions of Hazardous cargo...

Science.gov (United States)

2010-07-01

....94 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING General Working Conditions... 29 Labor 7 2010-07-01 2010-07-01 false Ventilation and atmospheric conditions (See also § 1918.2...

ProcSee - The Picasso successor

International Nuclear Information System (INIS)

Randem, Hans Olav; Jokstad, Haakon; Linden, Terje; Kvilesjoe, Hans Oeyvind; Rekvin, Sverre; Hornaes, Arne

2005-09-01

This report describes the history of computer graphics and Picasso at the Halden Project and how Picasso has been used at HRP, in HRP member organisations and in other organisations. It motivates the change of name from Picasso to ProcSee based on plans to extend the use of the product and to avoid a potential conflict regarding the name. It describes features introduced during the last years to motivate users to utilise new functionality, describes how tests shows that ProcSee has unique capabilities when it comes to performance for handling frequent display updates for large complex displays, and describes new planned features to be implemented in ProcSee. The report concludes that Picasso/ProcSee has been and will continue to be of vital importance for the HRP research programme within the fields of human-machine interface design and human-machine interaction. (Author)

Light-quark and gluon jet discrimination in [Formula: see text] collisions at [Formula: see text] with the ATLAS detector.

Science.gov (United States)

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A likelihood-based discriminant for the identification of quark- and gluon-initiated jets is built and validated using 4.7 fb[Formula: see text] of proton-proton collision data at [Formula: see text] [Formula: see text] collected with the ATLAS detector at the LHC. Data samples with enriched quark or gluon content are used in the construction and validation of templates of jet properties that are the input to the likelihood-based discriminant. The discriminating power of the jet tagger is established in both data and Monte Carlo samples within a systematic uncertainty of [Formula: see text] 10-20 %. In data, light-quark jets can be tagged with an efficiency of [Formula: see text] while achieving a gluon-jet mis-tag rate of [Formula: see text] in a [Formula: see text] range between [Formula: see text] and [Formula: see text] for jets in the acceptance of the tracker. The rejection of gluon-jets found in the data is significantly below what is attainable using a Pythia 6 Monte Carlo simulation, where gluon-jet mis-tag rates of 10 % can be reached for a 50 % selection efficiency of light-quark jets using the same jet properties.

Perceptual Experience and Seeing-as

Directory of Open Access Journals (Sweden)

Daniel Enrique Kalpokas

2015-07-01

Full Text Available According to Rorty, Davidson and Brandom, to have an experience is to be caused by our senses to hold a perceptual belief. This article argues that the phenomenon of seeing-as cannot be explained by such a conception of perceptual experience. First, the notion of experience defended by the aforementioned authors is reconstructed. Second, the main features of what Wittgenstein called “seeing aspects” are briefly presented. Finally, several arguments are developed in order to support the main thesis of the article: seeing-as cannot be explained by the conception of experience defended by Rorty, Davidson and Brandom.

Simultaneous seeing measurements at Atacama

Science.gov (United States)

Uraguchi, Fumihiro; Motohara, Kentaro; Doi, Mamoru; Takato, Naruhisa; Miyashita, Akihiko; Tanabe, Toshihiko; Oyabu, Shinki; Soyano, Takao

2004-10-01

Institute of Astronomy, University of Tokyo is now planning to build a 6.5-m optical-infrared telescope in Atacama, Chile. This project is called "Univ. Tokyo Atacama Observatory (TAO)", and the site evaluation is now under way. As a part of this evaluation process, we started an investigation to compare the astronomical seeing at Atacama with that at Mauna Kea. Here, we report preliminary results of seeing measurements at several sites in Atacama, carried out on October 2003. In order to separate the temporal and site-to-site variation of the seeing, we used two sets of Differential Image Motion Monitors (DIMMs), each of which has two pairs of 7.4 cm sub-apertures with 20.5 cm separation. Three sites were investigated; the point near the TAO weather station (4,950m), the summit of Cello Chico (5,150m) and the point at 5,430m altitude on Cello Toco. Simultaneous measurements were carried out for three half nights out of four half nights measurements. Although the amount of our data is very limited, the results suggest following: 1) Seeing becomes better and more stable as time passing to midnight (eg. From 0."7 to 0."4 at V-band). 2) Higher altitude sites show better seeing than lower altitude sites.

Simultaneous Detection of Androgen and Estrogen Abuse in Breeding Animals by Gas Chromatography-Mass Spectrometry/Combustion/Isotope Ratio Mass Spectrometry (GC-MS/C/IRMS) Evaluated against Alternative Methods.

Science.gov (United States)

Janssens, Geert; Mangelinckx, Sven; Courtheyn, Dirk; De Kimpe, Norbert; Matthijs, Bert; Le Bizec, Bruno

2015-09-02

The administration of synthetic homologues of naturally occurring steroids can be demonstrated by measuring (13)C/(12)C isotopic ratios of their urinary metabolites. Gas chromatography-mass spectrometry/combustion/isotope ratio mass spectrometry (GC-MS/C/IRMS) was used in this study to appraise in a global approach isotopic deviations of two 17β-testosterone metabolites (17α-testosterone and etiocholanolone) and one 17β-estradiol metabolite (17α-estradiol) together with those of 5-androstene-3β,17α-diol as endogenous reference compound (ERC). Intermediate precisions of 0.35‰, 1.05‰, 0.35‰, and 0.21‰, respectively, were observed (n = 8). To assess the performance of the analytical method, a bull and a heifer were treated with 17β-testosterone propionate and 17β-estradiol-3-benzoate. The sensitivity of the method permitted the demonstration of 17β-estradiol treatment up to 24 days. For 17β-testosterone treatment, the detection windows were 3 days and 24 days for the bull and the heifer, respectively. The capability of GC-MS/C/IRMS to demonstrate natural steroid abuse for urinary steroids was eventually compared to those of mass spectrometry (LC-MS/MS) when measuring intact steroid esters in blood and hair.

22 CFR 92.2 - Description of overseas notarial functions of the Department of State, record of acts.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Description of overseas notarial functions of the Department of State, record of acts. 92.2 Section 92.2 Foreign Relations DEPARTMENT OF STATE LEGAL... officers of the Department of State is similar to the function of a notary public in the United States. See...

Putting your human resource department to work for you.

Science.gov (United States)

McConnell, C R

1991-06-01

As a staff function, human resources is organized as a service activity. Service activities render no patient care; they do not advance the work of the organization. However, they support the performance of the organization's work and in a practical sense become necessary. For example, if a pure service, such as building maintenance, did not exist, the facility's physical plant would gradually self-destruct. Similarly, without human resources to see to the maintenance of the work force, the overall suitability and capability of that work force will steadily erode. Recognize human resources for what it is--an essential service function required to help the organization run as efficiently as possible. Learn what the HR department does, and especially learn why the department does what it does. Provide input to the human resource department. Forge a continuing working relationship with the HR department, making it clear that you expect service from this essential service department. Challenge the HR department to do more, to do better, and to continually improve service--and put the human resource department to work for you and your employees.

Interação entre irmãos em situação de cuidados formais Siblings interaction in formal care situation

Directory of Open Access Journals (Sweden)

Eleonora Arnaud Pereira Ferreira

1999-01-01

Full Text Available Este trabalho teve como objetivo descrever as principais características de famílias onde os filhos mais velhos são responsabilizados pela execução das tarefas domésticas e pelo cuidado aos irmãos menores, durante a ausência dos pais. Participaram deste estudo vinte famílias residentes à Vila Paranoá, Distrito Federal, com filhos de um a dezesseis anos de idade. Os dados foram colhidos através de entrevistas e sessões de observação sistemática do comportamento em ambiente natural, realizadas durante o período de almoço. A análise se deteve na organização familiar, desempenho em tarefas domésticas e interação entre irmãos, tendo sido possível classificar as famílias em três grupos qualitativamente distintos. Os resultados são discutidos em termos da necessidade de se considerar fatores de ordem social na análise do grupo familiar.This research aims at describing the characteristics of families where older children are responsible for carrying out chores and looking after their younger siblings while in their parents absence. Twenty families from Vila Paranoá (a slum in the outskirts of Brasília, Brasil, with one to sixteen year-old children were the subjects of this study. The data were picked up from interviews and sessions of systematic observation of behavior in natural environment. These sessions were carried out during lunch time. The analysis placed emphasis on family organization, performance in home tasks and sibling interation. It has been possible to classify the families into three qualitative groups. The results are discussed in terms of need considering factors of social order in the analysis of family group.

Production of [Formula: see text] and [Formula: see text] mesons up to high transverse momentum in pp collisions at 2.76 TeV.

Science.gov (United States)

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Gonzalez, A S; Gonzalez, V; González-Zamora, P; Gorbunov, S; Görlich, L; Gotovac, S; Grabski, V; Graczykowski, L K; Graham, K L; Greiner, L; Grelli, A; Grigoras, C; Grigoriev, V; Grigoryan, A; Grigoryan, S; Grion, N; Gronefeld, J M; Grosa, F; Grosse-Oetringhaus, J F; Grosso, R; Gruber, L; Grull, F R; Guber, F; Guernane, R; Guerzoni, B; Gulbrandsen, K; Gunji, T; Gupta, A; Gupta, R; Guzman, I B; Haake, R; Hadjidakis, C; Hamagaki, H; Hamar, G; Hamon, J C; Harris, J W; Harton, A; Hatzifotiadou, D; Hayashi, S; Heckel, S T; Hellbär, E; Helstrup, H; Herghelegiu, A; Corral, G Herrera; Herrmann, F; Hess, B A; Hetland, K F; Hillemanns, H; Hippolyte, B; Hladky, J; Hohlweger, B; Horak, D; Hornung, S; Hosokawa, R; Hristov, P; Hughes, C; Humanic, T J; Hussain, N; Hussain, T; Hutter, D; Hwang, D S; Ilkaev, R; Inaba, M; Ippolitov, M; Irfan, M; Isakov, V; Ivanov, M; Ivanov, V; Izucheev, V; Jacak, B; Jacazio, N; Jacobs, P M; Jadhav, M B; Jadlovska, S; Jadlovsky, J; Jaelani, S; Jahnke, C; Jakubowska, M J; Janik, M A; Jayarathna, P H S Y; Jena, C; Jena, S; Jercic, M; Bustamante, R T Jimenez; Jones, P G; Jusko, A; Kalinak, P; Kalweit, A; Kamin, J; Kang, J H; Kaplin, V; Kar, S; Uysal, A Karasu; Karavichev, O; Karavicheva, T; Karayan, L; Karpechev, E; Kebschull, U; Keidel, R; Keijdener, D L D; Keil, M; Ketzer, B; Khan, P; Khan, S A; Khanzadeev, A; Kharlov, Y; Khatun, A; Khuntia, A; Kielbowicz, M M; Kileng, B; Kim, D; Kim, D W; Kim, D J; Kim, H; Kim, J S; Kim, J; Kim, M; Kim, M; Kim, S; Kim, T; Kirsch, S; Kisel, I; Kiselev, S; Kisiel, A; Kiss, G; Klay, J L; Klein, C; Klein, J; Klein-Bösing, C; Klewin, S; Kluge, A; Knichel, M L; Knospe, A G; Kobdaj, C; Kofarago, M; Kollegger, T; Kolojvari, A; Kondratiev, V; Kondratyeva, N; Kondratyuk, E; Konevskikh, A; Kopcik, M; Kour, M; Kouzinopoulos, C; Kovalenko, O; Kovalenko, V; Kowalski, M; Meethaleveedu, G Koyithatta; Králik, I; Kravčáková, A; Krivda, M; Krizek, F; Kryshen, E; Krzewicki, M; Kubera, A M; Kučera, V; Kuhn, C; Kuijer, P G; Kumar, A; Kumar, J; Kumar, L; Kumar, S; Kundu, S; Kurashvili, P; Kurepin, A; Kurepin, A B; Kuryakin, A; Kushpil, S; Kweon, M J; Kwon, Y; La Pointe, S L; La Rocca, P; Fernandes, C Lagana; Lakomov, I; Langoy, R; Lapidus, K; Lara, C; Lardeux, A; Lattuca, A; Laudi, E; Lavicka, R; Lazaridis, L; Lea, R; Leardini, L; Lee, S; Lehas, F; Lehner, S; Lehrbach, J; Lemmon, R C; Lenti, V; Leogrande, E; Monzón, I León; Lévai, P; Li, S; Li, X; Lien, J; Lietava, R; Lindal, S; Lindenstruth, V; Lippmann, C; Lisa, M A; Litichevskyi, V; Ljunggren, H M; Llope, W J; Lodato, D F; Loenne, P I; Loginov, V; Loizides, C; Loncar, P; Lopez, X; Torres, E López; Lowe, A; Luettig, P; Lunardon, M; Luparello, G; Lupi, M; Lutz, T H; Maevskaya, A; Mager, M; Mahajan, S; Mahmood, S M; Maire, A; Majka, R D; Malaev, M; Cervantes, I Maldonado; Malinina, L; Mal'Kevich, D; Malzacher, P; Mamonov, A; Manko, V; Manso, F; Manzari, V; Mao, Y; Marchisone, M; Mareš, J; Margagliotti, G V; Margotti, A; Margutti, J; Marín, A; Markert, C; Marquard, M; Martin, N A; Martinengo, P; Martinez, J A L; Martínez, M I; García, G Martínez; Pedreira, M Martinez; Mas, A; Masciocchi, S; Masera, M; Masoni, A; Mastroserio, A; Mathis, A M; Matyja, A; Mayer, C; Mazer, J; Mazzilli, M; Mazzoni, M A; Meddi, F; Melikyan, Y; Menchaca-Rocha, A; Meninno, E; Pérez, J Mercado; Meres, M; Mhlanga, S; Miake, Y; Mieskolainen, M M; Mihaylov, D L; Mikhaylov, K; Milano, L; Milosevic, J; Mischke, A; Mishra, A N; Miśkowiec, D; Mitra, J; Mitu, C M; Mohammadi, N; Mohanty, B; Khan, M Mohisin; Montes, E; De Godoy, D A Moreira; Moreno, L A P; Moretto, S; Morreale, A; Morsch, A; Muccifora, V; Mudnic, E; Mühlheim, D; Muhuri, S; Mukherjee, M; Mulligan, J D; Munhoz, M G; Münning, K; Munzer, R H; Murakami, H; Murray, S; Musa, L; Musinsky, J; Myers, C J; Naik, B; Nair, R; Nandi, B K; Nania, R; Nappi, E; Narayan, A; Naru, M U; da Luz, H Natal; Nattrass, C; Navarro, S R; Nayak, K; Nayak, R; Nayak, T K; Nazarenko, S; Nedosekin, A; De Oliveira, R A Negrao; Nellen, L; Nesbo, S V; Ng, F; Nicassio, M; Niculescu, M; Niedziela, J; Nielsen, B S; Nikolaev, S; Nikulin, S; Nikulin, V; Noferini, F; Nomokonov, P; Nooren, G; Noris, J C C; Norman, J; Nyanin, A; Nystrand, J; Oeschler, H; Oh, S; Ohlson, A; Okubo, T; Olah, L; Oleniacz, J; Da Silva, A C Oliveira; Oliver, M H; Onderwaater, J; Oppedisano, C; Orava, R; Oravec, M; Velasquez, A Ortiz; Oskarsson, A; Otwinowski, J; Oyama, K; Pachmayer, Y; Pacik, V; Pagano, D; Pagano, P; Paić, G; Palni, P; Pan, J; Pandey, A K; Panebianco, S; Papikyan, V; Pappalardo, G S; Pareek, P; Park, J; Park, W J; Parmar, S; Passfeld, A; Pathak, S P; Paticchio, V; Patra, R N; Paul, B; Pei, H; Peitzmann, T; Peng, X; Pereira, L G; Da Costa, H Pereira; Peresunko, D; Lezama, E Perez; Peskov, V; Pestov, Y; Petráček, V; Petrov, V; Petrovici, M; Petta, C; Pezzi, R P; Piano, S; Pikna, M; Pillot, P; Pimentel, L O D L; Pinazza, O; Pinsky, L; Piyarathna, D B; Oskoń, M Pł; Planinic, M; Pluta, J; Pochybova, S; Podesta-Lerma, P L M; Poghosyan, M G; Polichtchouk, B; Poljak, N; Poonsawat, W; Pop, A; Poppenborg, H; Porteboeuf-Houssais, S; Porter, J; Pospisil, J; Pozdniakov, V; Prasad, S K; Preghenella, R; Prino, F; Pruneau, C A; Pshenichnov, I; Puccio, M; Puddu, G; Pujahari, P; Punin, V; Putschke, J; Qvigstad, H; Rachevski, A; Raha, S; Rajput, S; Rak, J; Rakotozafindrabe, A; Ramello, L; Rami, F; Rana, D B; Raniwala, R; Raniwala, S; Räsänen, S S; Rascanu, B T; Rathee, D; Ratza, V; Ravasenga, I; Read, K F; Redlich, K; Rehman, A; Reichelt, P; Reidt, F; Ren, X; Renfordt, R; Reolon, A R; Reshetin, A; Reygers, K; Riabov, V; Ricci, R A; Richert, T; Richter, M; Riedler, P; Riegler, W; Riggi, F; Ristea, C; Cahuantzi, M Rodríguez; Røed, K; Rogochaya, E; Rohr, D; Röhrich, D; Rokita, P S; Ronchetti, F; Ronflette, L; Rosnet, P; Rossi, A; Rotondi, A; Roukoutakis, F; Roy, A; Roy, C; Roy, P; Montero, A J Rubio; Rueda, O V; Rui, R; Russo, R; Rustamov, A; Ryabinkin, E; Ryabov, Y; Rybicki, A; Saarinen, S; Sadhu, S; Sadovsky, S; Šafařík, K; Saha, S K; Sahlmuller, B; Sahoo, B; Sahoo, P; Sahoo, R; Sahoo, S; Sahu, P K; Saini, J; Sakai, S; Saleh, M A; Salzwedel, J; Sambyal, S; Samsonov, V; Sandoval, A; Sarkar, D; Sarkar, N; Sarma, P; Sas, M H P; Scapparone, E; Scarlassara, F; Scharenberg, R P; Scheid, H S; Schiaua, C; Schicker, R; Schmidt, C; Schmidt, H R; Schmidt, M O; Schmidt, M; Schuchmann, S; Schukraft, J; Schutz, Y; Schwarz, K; Schweda, K; Scioli, G; Scomparin, E; Scott, R; Šefčík, M; Seger, J E; Sekiguchi, Y; Sekihata, D; Selyuzhenkov, I; Senosi, K; Senyukov, S; Serradilla, E; Sett, P; Sevcenco, A; Shabanov, A; Shabetai, A; Shadura, O; Shahoyan, R; Shangaraev, A; Sharma, A; Sharma, A; Sharma, M; Sharma, M; Sharma, N; Sheikh, A I; Shigaki, K; Shou, Q; Shtejer, K; Sibiriak, Y; Siddhanta, S; Sielewicz, K M; Siemiarczuk, T; Silvermyr, D; Silvestre, C; Simatovic, G; Simonetti, G; Singaraju, R; Singh, R; Singhal, V; Sinha, T; Sitar, B; Sitta, M; Skaali, T B; Slupecki, M; Smirnov, N; Snellings, R J M; Snellman, T W; Song, J; Song, M; Soramel, F; Sorensen, S; Sozzi, F; Spiriti, E; Sputowska, I; Srivastava, B K; Stachel, J; Stan, I; Stankus, P; Stenlund, E; Stiller, J H; Stocco, D; Strmen, P; Suaide, A A P; Sugitate, T; Suire, C; Suleymanov, M; Suljic, M; Sultanov, R; Šumbera, M; Sumowidagdo, S; Suzuki, K; Swain, S; Szabo, A; Szarka, I; Szczepankiewicz, A; Szymanski, M; Tabassam, U; Takahashi, J; Tambave, G J; Tanaka, N; Tarhini, M; Tariq, M; Tarzila, M G; Tauro, A; Muñoz, G Tejeda; Telesca, A; Terasaki, K; Terrevoli, C; Teyssier, B; Thakur, D; Thakur, S; Thomas, D; Tieulent, R; Tikhonov, A; Timmins, A R; Toia, A; Tripathy, S; Trogolo, S; Trombetta, G; Trubnikov, V; Trzaska, W H; Trzeciak, B A; Tsuji, T; Tumkin, A; Turrisi, R; Tveter, T S; Ullaland, K; Umaka, E N; Uras, A; Usai, G L; Utrobicic, A; Vala, M; Van Der Maarel, J; Van Hoorne, J W; van Leeuwen, M; Vanat, T; Vyvre, P Vande; Varga, D; Vargas, A; Vargyas, M; Varma, R; Vasileiou, M; Vasiliev, A; Vauthier, A; Doce, O Vázquez; Vechernin, V; Veen, A M; Velure, A; Vercellin, E; Limón, S Vergara; Vernet, R; Vértesi, R; Vickovic, L; Vigolo, S; Viinikainen, J; Vilakazi, Z; Baillie, O Villalobos; Tello, A Villatoro; Vinogradov, A; Vinogradov, L; Virgili, T; Vislavicius, V; Vodopyanov, A; Völkl, M A; Voloshin, K; Voloshin, S A; Volpe, G; von Haller, B; Vorobyev, I; Voscek, D; Vranic, D; Vrláková, J; Wagner, B; Wagner, J; Wang, H; Wang, M; Watanabe, D; Watanabe, Y; Weber, M; Weber, S G; Weiser, D F; Wessels, J P; Westerhoff, U; Whitehead, A M; Wiechula, J; Wikne, J; Wilk, G; Wilkinson, J; Willems, G A; Williams, M C S; Windelband, B; Witt, W E; Yalcin, S; Yang, P; Yano, S; Yin, Z; Yokoyama, H; Yoo, I-K; Yoon, J H; Yurchenko, V; Zaccolo, V; Zaman, A; Zampolli, C; Zanoli, H J C; Zardoshti, N; Zarochentsev, A; Závada, P; Zaviyalov, N; Zbroszczyk, H; Zhalov, M; Zhang, H; Zhang, X; Zhang, Y; Zhang, C; Zhang, Z; Zhao, C; Zhigareva, N; Zhou, D; Zhou, Y; Zhou, Z; Zhu, H; Zhu, J; Zhu, X; Zichichi, A; Zimmermann, A; Zimmermann, M B; Zimmermann, S; Zinovjev, G; Zmeskal, J

2017-01-01

The invariant differential cross sections for inclusive [Formula: see text] and [Formula: see text] mesons at midrapidity were measured in pp collisions at [Formula: see text] TeV for transverse momenta [Formula: see text] GeV/ c and [Formula: see text] GeV/ c , respectively, using the ALICE detector. This large range in [Formula: see text] was achieved by combining various analysis techniques and different triggers involving the electromagnetic calorimeter (EMCal). In particular, a new single-cluster, shower-shape based method was developed for the identification of high-[Formula: see text] neutral pions, which exploits that the showers originating from their decay photons overlap in the EMCal. Above 4 GeV/[Formula: see text], the measured cross sections are found to exhibit a similar power-law behavior with an exponent of about 6.3. Next-to-leading-order perturbative QCD calculations differ from the measured cross sections by about 30% for the [Formula: see text], and between 30-50% for the [Formula: see text] meson, while generator-level simulations with PYTHIA 8.2 describe the data to better than 10-30%, except at [Formula: see text] GeV/[Formula: see text]. The new data can therefore be used to further improve the theoretical description of [Formula: see text] and [Formula: see text] meson production.

Ammonia IRMS-TPD measurements and DFT calculation on acidic hydroxyl groups in CHA-type zeolites.

Science.gov (United States)

Suzuki, Katsuki; Sastre, German; Katada, Naonobu; Niwa, Miki

2007-12-07

Brønsted acidity of H-chabazite (CHA) zeolites (Si : Al(2) = 4.2) was investigated by means of ammonia infrared-mass spectrometry/temperature-programmed desorption (IRMS-TPD) methods and density functional calculations. Four IR bands were observed at 3644, 3616, 3575 and 3538 cm(-1), and they were ascribable to the acidic OH groups on four nonequivalent oxygen sites in the CHA structure. The absorption band at 3538 cm(-1) was attributed to the O(4)H in the 6-membered ring (MR), and ammonia adsorption energy (DeltaU) of this OH group was the lowest among the 4 kinds of OH groups. The other 3 bands were assigned to the acidic OH groups in 8MR. It was observed that the DeltaU in 8 and 6MR were 131 (+/-3) and 101 kJ mol(-1), respectively. On the other hand, the density functional theory (DFT) calculations within periodic boundary conditions yielded the adsorption energies on these OH groups in 8 and 6MR to be ca. 130 and 110 kJ mol(-1), respectively, in good agreement with the experimentally-observed values.

Classification of Coffee Beans by GC-C-IRMS, GC-MS, and 1H-NMR

Science.gov (United States)

Arana, Victoria Andrea; Esseiva, Pierre; Pazos, Diego

2016-01-01

In a previous work using 1H-NMR we reported encouraging steps towards the construction of a robust expert system for the discrimination of coffees from Colombia versus nearby countries (Brazil and Peru), to assist the recent protected geographical indication granted to Colombian coffee in 2007. This system relies on fingerprints acquired on a 400 MHz magnet and is thus well suited for small scale random screening of samples obtained at resellers or coffee shops. However, this approach cannot easily be implemented at harbour's installations, due to the elevated operational costs of cryogenic magnets. This limitation implies shipping the samples to the NMR laboratory, making the overall approach slower and thereby more expensive and less attractive for large scale screening at harbours. In this work, we report on our attempt to obtain comparable classification results using alternative techniques that have been reported promising as an alternative to NMR: GC-MS and GC-C-IRMS. Although statistically significant information could be obtained by all three methods, the results show that the quality of the classifiers depends mainly on the number of variables included in the analysis; hence NMR provides an advantage since more molecules are detected to obtain a model with better predictions. PMID:27516919

Classification of Coffee Beans by GC-C-IRMS, GC-MS, and (1)H-NMR.

Science.gov (United States)

Arana, Victoria Andrea; Medina, Jessica; Esseiva, Pierre; Pazos, Diego; Wist, Julien

2016-01-01

In a previous work using (1)H-NMR we reported encouraging steps towards the construction of a robust expert system for the discrimination of coffees from Colombia versus nearby countries (Brazil and Peru), to assist the recent protected geographical indication granted to Colombian coffee in 2007. This system relies on fingerprints acquired on a 400 MHz magnet and is thus well suited for small scale random screening of samples obtained at resellers or coffee shops. However, this approach cannot easily be implemented at harbour's installations, due to the elevated operational costs of cryogenic magnets. This limitation implies shipping the samples to the NMR laboratory, making the overall approach slower and thereby more expensive and less attractive for large scale screening at harbours. In this work, we report on our attempt to obtain comparable classification results using alternative techniques that have been reported promising as an alternative to NMR: GC-MS and GC-C-IRMS. Although statistically significant information could be obtained by all three methods, the results show that the quality of the classifiers depends mainly on the number of variables included in the analysis; hence NMR provides an advantage since more molecules are detected to obtain a model with better predictions.

The use of IRMS, (1)H NMR and chemical analysis to characterise Italian and imported Tunisian olive oils.

Science.gov (United States)

Camin, Federica; Pavone, Anita; Bontempo, Luana; Wehrens, Ron; Paolini, Mauro; Faberi, Angelo; Marianella, Rosa Maria; Capitani, Donatella; Vista, Silvia; Mannina, Luisa

2016-04-01

Isotope Ratio Mass Spectrometry (IRMS), (1)H Nuclear Magnetic Resonance ((1)H NMR), conventional chemical analysis and chemometric elaboration were used to assess quality and to define and confirm the geographical origin of 177 Italian PDO (Protected Denomination of Origin) olive oils and 86 samples imported from Tunisia. Italian olive oils were richer in squalene and unsaturated fatty acids, whereas Tunisian olive oils showed higher δ(18)O, δ(2)H, linoleic acid, saturated fatty acids β-sitosterol, sn-1 and 3 diglyceride values. Furthermore, all the Tunisian samples imported were of poor quality, with a K232 and/or acidity values above the limits established for extra virgin olive oils. By combining isotopic composition with (1)H NMR data using a multivariate statistical approach, a statistical model able to discriminate olive oil from Italy and those imported from Tunisia was obtained, with an optimal differentiation ability arriving at around 98%. Copyright © 2015 Elsevier Ltd. All rights reserved.

Holy See participation in the IAEA

International Nuclear Information System (INIS)

1969-01-01

The Holy See has participated in every General Conference of the IAEA and has made a special contribution in Vienna to international co-operation and the development of the peaceful atom. On August 20, 1957 the Holy See became a full member of the Agency. (author)

Can Computers See?

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 4; Issue 6. Can Computers See? - Can Computers Understand Visual Data? Neelima Shrikhande. General Article Volume 4 Issue 6 June 1999 pp 45-56. Fulltext. Click here to view fulltext PDF. Permanent link:

Steroid profile and IRMS analysis of musk administration for doping control.

Science.gov (United States)

Wang, Jingzhu; He, Yi; Liu, Xin; Yang, Zhiyong; Yang, Wenning

2017-11-01

Musk, the dried secretion of the musk pod (sac) of adult male musk deer, has been used as traditional Chinese Medicine (TCM) in China and south-east Asian countries for thousands of years. Due to the anabolic steroid component in this TCM, musk preparations have been included in the list of medical products containing prohibited substances employed for doping by the State Food and Drug Administration of China. The application of musk pod formulation was claimed to be responsible for some adverse analytical findings (AAFs) in the 2011 FIFA Women's World Cup. Our preliminary study has suggested that musk ingestion did not lead to AAFs of doping control with the single dosage of 100 mg. However, the influences of musk administration in large and multi dosage are still unclear. The aim of this study is to further investigate the influences of musk administration for doping control. Wild and domestic deer musk samples were collected. The concentrations and δ 13 C-values of steroids in musk were analyzed. In an excretion study, 200 and 100 mg of wild and domestic deer musk samples were administrated by 29 subjects, respectively. Fluctuations in steroid profile could be observed, and the ratio of 5α-androstane-3α,17β-diol to 5β-androstane-3α,17β-diol was more sensitive than other parameters. In the IRMS test, the ∆Δδ 13 C-value between endogenous reference compound and etiocholanolone was a sensitive parameter, and AAFs were obtained. It is the first time to confirm with excretion study that musk administration could lead to positive result of doping control. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

1993 Department of Energy Records Management Conference

Energy Technology Data Exchange (ETDEWEB)

NONE

1993-12-31

This document consists of viewgraphs from the presentations at the conference. Topics included are: DOE records management overview, NIRMA and ARMA resources, NARA records management training, potential quality assurance records, filing systems, organizing and indexing technical records, DOE-HQ initiatives, IRM reviews, status of epidemiologic inventory, disposition of records and personal papers, inactive records storage, establishing administrative records, managing records at Hanford, electronic mail -- legal and records issues, NARA-GAO reports status, consultive selling, automated indexing, decentralized approach to scheduling at a DOE office, developing specific records management programs, storage and retrieval at Savannah River Plant, an optical disk case study, and special interest group reports.

Reconstructing see-saw models

International Nuclear Information System (INIS)

Ibarra, Alejandro

2007-01-01

In this talk we discuss the prospects to reconstruct the high-energy see-saw Lagrangian from low energy experiments in supersymmetric scenarios. We show that the model with three right-handed neutrinos could be reconstructed in theory, but not in practice. Then, we discuss the prospects to reconstruct the model with two right-handed neutrinos, which is the minimal see-saw model able to accommodate neutrino observations. We identify the relevant processes to achieve this goal, and comment on the sensitivity of future experiments to them. We find the prospects much more promising and we emphasize in particular the importance of the observation of rare leptonic decays for the reconstruction of the right-handed neutrino masses

MELLIPHEROUS TREES MONITORING FROM ANA LUGOJANA FORESTRY DEPARTMENTS

Directory of Open Access Journals (Sweden)

SILVIA PĂTRUICĂ

2007-10-01

Full Text Available This paper presents the results of a study made by the purpose of seeing in whatmanner the mellipherous trees belonging to Ana Lugojana Departments ensuremaintenance and production harvesting for bee families from this area. The study wasmade during the period of May 2006 and April 2007, on a 12301 hectares area, inwhich we recorded: forestry mellipherous trees identification, the surface occupied byeach specie and the blooming period, data that we used to calculate the amount ofhoney that can be obtained and the number of bee families that can be kept in thearea, respectively. Analyzing the data, we concluded that forestry mellipherous treesfrom Ana Lugojana Forestry Departments can ensure in normal conditions,maintenance and production harvesting for 3239 bee families.

Nódulo umbilical metastático (nódulo da Irmã Maria José: um sinal de alerta para tumoração maligna intra-abdominal - relato de caso Sister Mary Joseph's nodule: a warning sign for intra-abdominal malignant tumors. A case report

Directory of Open Access Journals (Sweden)

Homero Soares Fogaça

2003-07-01

Full Text Available O nódulo da "Irmã Maria José" é tumor metastático que acomete a cicatriz umbilical e pode ser a primeira evidência de neoplasia intra-abdominal disseminada. Os autores relatam o caso de uma paciente com o nódulo da "Irmã Maria José" no qual o diagnóstico do tumor primário só foi possível por meio dos testes imuno-histoquímicos da lesão biopsiada da pele.The umbilical metastatic tumoral nodule, Sister Mary Joseph's nodule, is a rare clinical sign indicative of disseminated intra-abdominal tumor, and may be the first evidence of malignancy. The authors report a case of a patient with umbilical metastatic nodule in whom the diagnosis of the primary tumor was possible by immunohistochemistry of the lesion biopsy.

Sample exchange/evaluation (SEE) report - Phase III

International Nuclear Information System (INIS)

Winters, W.I.

1996-01-01

This report describes the results from Phase III of the Sample Exchange Evaluation (SEE) program. The SEE program is used to compare analytical laboratory performance on samples from the Hanford Site's high level waste tanks

Determination of authenticity, regional origin, and vintage of Slovenian wines using a combination of IRMS and SNIF-NMR analyses.

Science.gov (United States)

Ogrinc, N; Kosir, I J; Kocjancic, M; Kidric, J

2001-03-01

The authenticity and geographical origin of wines produced in Slovenia were investigated by a combination of IRMS and SNIF-NMR methods. A total of 102 grape samples of selected wines were carefully collected in three different wine-growing regions of Slovenia in 1996, 1997, and 1998. The stable isotope data were evaluated using principal component analysis (PCA) and linear discriminant analysis (LDA). The isotopic ratios to discriminate between coastal and continental regions are the deuterium/hydrogen isotopic ratio of the methylene site in the ethanol molecule (D/H)(II) and delta(13)C values; including also delta(18)O values in the PCA and LDA made possible separation between the two continental regions Drava and Sava. It was found that delta(18)O values are modified by the meteorological events during grape ripening and harvest. The usefulness of isotopic parameters for detecting adulteration or watering and to assess the geographical origin of wines is improved only when they are used concurrently.

How we see poverty

Directory of Open Access Journals (Sweden)

Jonathan Morduch

2012-06-01

Full Text Available How we think about poverty is colored by how we measure it. For economists, that often means seeing poverty through quantities measured in large, representative surveys.  The surveys give a comprehensive view, but favor breadth over depth. Typical economic surveys are limited in their ability to tease out informal activity, and, while they capture yearly sums, they offer little about how the year was actually lived by families. Year-long financial diaries provide a complementary way of seeing poverty, with a focus on week by week choices and challenges. The result is a re-framing of poverty and its relationship to money, calling for greater attention to financial access and a broader notion of how finance matters.

On some binomial [Formula: see text]-difference sequence spaces.

Science.gov (United States)

Meng, Jian; Song, Meimei

2017-01-01

In this paper, we introduce the binomial sequence spaces [Formula: see text], [Formula: see text] and [Formula: see text] by combining the binomial transformation and difference operator. We prove the BK -property and some inclusion relations. Furthermore, we obtain Schauder bases and compute the α -, β - and γ -duals of these sequence spaces. Finally, we characterize matrix transformations on the sequence space [Formula: see text].

13 C analysis of aromas and perfumes by a coupled GC-IRMS technique. The case of vanillin and leaf alcohol extracts

International Nuclear Information System (INIS)

Breas, O.; Fourel, F.; Martin, G.J.

1994-01-01

The determination of stable isotope ratios is a precious tool to establish the natural status of flavors and fragrances. Results are presented concerning δ 13 C measurements using gas chromatography-combustion interface-isotope ratio mass spectrometry (GC-C- 13 C IRMS). This technique allows to measure carbon isotope ratios on pure compounds separated by capillary gas chromatography and injected on-line into an isotopic mass spectrometer. δ 13 C measurements carried out on vanilla extracts require only very small quantities of compounds ( 13 C measurements performed on cis-3-hexanol extracted from mint, the difference between natural and synthetic cis-3-hexanol is underlined and it is demonstrated that reproducible isotope ratios may be measured for cis-3-hexanol on mint extracts without purification even if this compound only represents 0.5% of the extract. (authors). 17 refs., 1 fig., 3 tabs

Study of the production of charged pions, kaons, and protons in pPb collisions at [Formula: see text]5.02[Formula: see text].

Science.gov (United States)

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Spectra of identified charged hadrons are measured in pPb collisions with the CMS detector at the LHC at [Formula: see text]. Charged pions, kaons, and protons in the transverse-momentum range [Formula: see text]-1.7[Formula: see text] and laboratory rapidity [Formula: see text] are identified via their energy loss in the silicon tracker. The average [Formula: see text] increases with particle mass and the charged multiplicity of the event. The increase of the average [Formula: see text] with charged multiplicity is greater for heavier hadrons. Comparisons to Monte Carlo event generators reveal that Epos Lhc, which incorporates additional hydrodynamic evolution of the created system, is able to reproduce most of the data features, unlike Hijing and Ampt. The [Formula: see text] spectra and integrated yields are also compared to those measured in pp and PbPb collisions at various energies. The average transverse momentum and particle ratio measurements indicate that particle production at LHC energies is strongly correlated with event particle multiplicity.

Search for lepton flavour violating decays of heavy resonances and quantum black holes to an [Formula: see text] pair in proton-proton collisions at [Formula: see text].

Science.gov (United States)

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Demiroglu, Z S; Dozen, C; Dumanoglu, I; Girgis, S; Gokbulut, G; Guler, Y; Gurpinar, E; Hos, I; Kangal, E E; Kayis Topaksu, A; Onengut, G; Ozdemir, K; Ozturk, S; Tali, B; Topakli, H; Zorbilmez, C; Bilin, B; Bilmis, S; Isildak, B; Karapinar, G; Yalvac, M; Zeyrek, M; Gülmez, E; Kaya, M; Kaya, O; Yetkin, E A; Yetkin, T; Cakir, A; Cankocak, K; Sen, S; Vardarlı, F I; Grynyov, B; Levchuk, L; Sorokin, P; Aggleton, R; Ball, F; Beck, L; Brooke, J J; Clement, E; Cussans, D; Flacher, H; Goldstein, J; Grimes, M; Heath, G P; Heath, H F; Jacob, J; Kreczko, L; Lucas, C; Meng, Z; Newbold, D M; Paramesvaran, S; Poll, A; Sakuma, T; Seif El Nasr-Storey, S; Senkin, S; Smith, D; Smith, V J; Bell, K W; Belyaev, A; Brew, C; Brown, R M; Calligaris, L; Cieri, D; Cockerill, D J A; Coughlan, J A; Harder, K; Harper, S; Olaiya, E; Petyt, D; Shepherd-Themistocleous, C H; Thea, A; Tomalin, I R; Williams, T; Worm, S D; Baber, M; Bainbridge, R; Buchmuller, O; Bundock, A; Burton, D; Casasso, S; Citron, M; Colling, D; Corpe, L; 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Pilot, J; Ricci-Tam, F; Shalhout, S; Smith, J; Squires, M; Stolp, D; Tripathi, M; Wilbur, S; Yohay, R; Cousins, R; Everaerts, P; Florent, A; Hauser, J; Ignatenko, M; Saltzberg, D; Takasugi, E; Valuev, V; Weber, M; Burt, K; Clare, R; Ellison, J; Gary, J W; Hanson, G; Heilman, J; Ivova Paneva, M; Jandir, P; Kennedy, E; Lacroix, F; Long, O R; Malberti, M; Negrete, M Olmedo; Shrinivas, A; Wei, H; Wimpenny, S; Yates, B R; Branson, J G; Cerati, G B; Cittolin, S; D'Agnolo, R T; Derdzinski, M; Holzner, A; Kelley, R; Klein, D; Letts, J; Macneill, I; Olivito, D; Padhi, S; Pieri, M; Sani, M; Sharma, V; Simon, S; Tadel, M; Vartak, A; Wasserbaech, S; Welke, C; Würthwein, F; Yagil, A; Zevi Della Porta, G; Bradmiller-Feld, J; Campagnari, C; Dishaw, A; Dutta, V; Flowers, K; Franco Sevilla, M; Geffert, P; George, C; Golf, F; Gouskos, L; Gran, J; Incandela, J; Mccoll, N; Mullin, S D; Richman, J; Stuart, D; Suarez, I; West, C; Yoo, J; Anderson, D; Apresyan, A; Bornheim, A; Bunn, J; Chen, Y; Duarte, J; Mott, A; Newman, H B; Pena, C; Spiropulu, M; Vlimant, J R; Xie, S; Zhu, R Y; Andrews, M B; Azzolini, V; Calamba, A; Carlson, B; Ferguson, T; Paulini, M; Russ, J; Sun, M; Vogel, H; Vorobiev, I; Cumalat, J P; Ford, W T; Gaz, A; Jensen, F; Johnson, A; Krohn, M; Mulholland, T; Nauenberg, U; Stenson, K; Wagner, S R; Alexander, J; Chatterjee, A; Chaves, J; Chu, J; Dittmer, S; Eggert, N; Mirman, N; Nicolas Kaufman, G; Patterson, J R; Rinkevicius, A; Ryd, A; Skinnari, L; Soffi, L; Sun, W; Tan, S M; Teo, W D; Thom, J; Thompson, J; Tucker, J; Weng, Y; Wittich, P; Abdullin, S; Albrow, M; Apollinari, G; Banerjee, S; Bauerdick, L A T; Beretvas, A; Berryhill, J; Bhat, P C; Bolla, G; Burkett, K; Butler, J N; Cheung, H W K; Chlebana, F; Cihangir, S; Elvira, V D; Fisk, I; Freeman, J; Gottschalk, E; Gray, L; Green, D; Grünendahl, S; Gutsche, O; Hanlon, J; Hare, D; Harris, R M; Hasegawa, S; Hirschauer, J; Hu, Z; Jayatilaka, B; Jindariani, S; Johnson, M; Joshi, U; Klima, B; Kreis, B; Lammel, S; Lewis, J; Linacre, J; Lincoln, D; Lipton, R; Liu, T; Lopes De Sá, R; Lykken, J; Maeshima, K; Marraffino, J M; Maruyama, S; Mason, D; McBride, P; Merkel, P; Mrenna, S; Nahn, S; Newman-Holmes, C; O'Dell, V; Pedro, K; Prokofyev, O; Rakness, G; Sexton-Kennedy, E; Soha, A; Spalding, W J; Spiegel, L; Stoynev, S; Strobbe, N; Taylor, L; Tkaczyk, S; Tran, N V; Uplegger, L; Vaandering, E W; Vernieri, C; Verzocchi, M; Vidal, R; Wang, M; Weber, H A; Whitbeck, A; Acosta, D; Avery, P; Bortignon, P; Bourilkov, D; Brinkerhoff, A; Carnes, A; Carver, M; Curry, D; Das, S; Field, R D; Furic, I K; Konigsberg, J; Korytov, A; Kotov, K; Ma, P; Matchev, K; Mei, H; Milenovic, P; Mitselmakher, G; Rank, D; Rossin, R; Shchutska, L; Snowball, M; Sperka, D; Terentyev, N; Thomas, L; Wang, J; Wang, S; Yelton, J; Hewamanage, S; Linn, S; Markowitz, P; Martinez, G; Rodriguez, J L; Ackert, A; Adams, J R; Adams, T; Askew, A; Bein, S; Bochenek, J; Diamond, B; Haas, J; Hagopian, S; Hagopian, V; Johnson, K F; Khatiwada, A; Prosper, H; Weinberg, M; Baarmand, M M; Bhopatkar, V; Colafranceschi, S; Hohlmann, M; Kalakhety, H; Noonan, D; Roy, T; Yumiceva, F; Adams, M R; Apanasevich, L; Berry, D; Betts, R R; Bucinskaite, I; Cavanaugh, R; Evdokimov, O; Gauthier, L; Gerber, C E; Hofman, D J; Kurt, P; O'Brien, C; Sandoval Gonzalez, L D; Turner, P; Varelas, N; Wu, Z; Zakaria, M; Zhang, J; Bilki, B; Clarida, W; Dilsiz, K; Durgut, S; Gandrajula, R P; Haytmyradov, M; Khristenko, V; Merlo, J-P; Mermerkaya, H; Mestvirishvili, A; Moeller, A; Nachtman, J; Ogul, H; Onel, Y; Ozok, F; Penzo, A; Snyder, C; Tiras, E; Wetzel, J; Yi, K; Anderson, I; Barnett, B A; Blumenfeld, B; Cocoros, A; Eminizer, N; Fehling, D; Feng, L; Gritsan, A V; Maksimovic, P; Osherson, M; Roskes, J; Sarica, U; Swartz, M; Xiao, M; Xin, Y; You, C; Baringer, P; Bean, A; Bruner, C; Kenny, R P; Majumder, D; Malek, M; Mcbrayer, W; Murray, M; Sanders, S; Stringer, R; Wang, Q; Ivanov, A; Kaadze, K; Khalil, S; Makouski, M; Maravin, Y; Mohammadi, A; Saini, L K; Skhirtladze, N; Toda, S; Lange, D; Rebassoo, F; Wright, D; Anelli, C; Baden, A; Baron, O; Belloni, A; Calvert, B; Eno, S C; Ferraioli, C; Gomez, J A; Hadley, N J; Jabeen, S; Kellogg, R G; Kolberg, T; Kunkle, J; Lu, Y; Mignerey, A C; Shin, Y H; Skuja, A; Tonjes, M B; Tonwar, S C; Apyan, A; Barbieri, R; Baty, A; Bi, R; Bierwagen, K; Brandt, S; Busza, W; Cali, I A; Demiragli, Z; Di Matteo, L; Gomez Ceballos, G; Goncharov, M; Gulhan, D; Iiyama, Y; Innocenti, G M; Klute, M; Kovalskyi, D; Lai, Y S; Lee, Y-J; Levin, A; Luckey, P D; Marini, A C; Mcginn, C; Mironov, C; Narayanan, S; Niu, X; Paus, C; Roland, C; Roland, G; Salfeld-Nebgen, J; Stephans, G S F; Sumorok, K; Tatar, K; Varma, M; Velicanu, D; Veverka, J; Wang, J; Wang, T W; Wyslouch, B; Yang, M; Zhukova, V; Benvenuti, A C; Dahmes, B; Evans, A; Finkel, A; Gude, A; Hansen, P; Kalafut, S; Kao, S C; Klapoetke, K; Kubota, Y; Lesko, Z; Mans, J; Nourbakhsh, S; Ruckstuhl, N; Rusack, R; Tambe, N; Turkewitz, J; Acosta, J G; Oliveros, S; Avdeeva, E; Bartek, R; Bloom, K; Bose, S; Claes, D R; Dominguez, A; Fangmeier, C; Gonzalez Suarez, R; Kamalieddin, R; Knowlton, D; Kravchenko, I; Meier, F; Monroy, J; Ratnikov, F; Siado, J E; Snow, G R; Alyari, M; Dolen, J; George, J; Godshalk, A; Harrington, C; Iashvili, I; Kaisen, J; Kharchilava, A; Kumar, A; Rappoccio, S; Roozbahani, B; Alverson, G; Barberis, E; Baumgartel, D; Chasco, M; Hortiangtham, A; Massironi, A; Morse, D M; Nash, D; Orimoto, T; Teixeira De Lima, R; Trocino, D; Wang, R-J; Wood, D; Zhang, J; Bhattacharya, S; Hahn, K A; Kubik, A; Low, J F; Mucia, N; Odell, N; Pollack, B; Schmitt, M; Sung, K; Trovato, M; Velasco, M; Dev, N; Hildreth, M; Jessop, C; Karmgard, D J; Kellams, N; Lannon, K; Marinelli, N; Meng, F; Mueller, C; Musienko, Y; Planer, M; Reinsvold, A; Ruchti, R; Smith, G; Taroni, S; Valls, N; Wayne, M; Wolf, M; Woodard, A; Antonelli, L; Brinson, J; Bylsma, B; Durkin, L S; Flowers, S; Hart, A; Hill, C; Hughes, R; Ji, W; Ling, T Y; Liu, B; Luo, W; Puigh, D; Rodenburg, M; Winer, B L; Wulsin, H W; Driga, O; Elmer, P; Hardenbrook, J; Hebda, P; Koay, S A; Lujan, P; Marlow, D; Medvedeva, T; Mooney, M; Olsen, J; Palmer, C; Piroué, P; Stickland, D; Tully, C; Zuranski, A; Malik, S; Barker, A; Barnes, V E; Benedetti, D; Bortoletto, D; Gutay, L; Jha, M K; Jones, M; Jung, A W; Jung, K; Kumar, A; Miller, D H; Neumeister, N; Radburn-Smith, B C; Shi, X; Shipsey, I; Silvers, D; Sun, J; Svyatkovskiy, A; Wang, F; Xie, W; Xu, L; Parashar, N; Stupak, J; Adair, A; Akgun, B; Chen, Z; Ecklund, K M; Geurts, F J M; Guilbaud, M; Li, W; Michlin, B; Northup, M; Padley, B P; Redjimi, R; Roberts, J; Rorie, J; Tu, Z; Zabel, J; Betchart, B; Bodek, A; de Barbaro, P; Demina, R; Eshaq, Y; Ferbel, T; Galanti, M; Garcia-Bellido, A; Han, J; Hindrichs, O; Khukhunaishvili, A; Lo, K H; Tan, P; Verzetti, M; Chou, J P; Contreras-Campana, E; Ferencek, D; Gershtein, Y; Halkiadakis, E; Heindl, M; Hidas, D; Hughes, E; Kaplan, S; Kunnawalkam Elayavalli, R; Lath, A; Nash, K; Saka, H; Salur, S; Schnetzer, S; Sheffield, D; Somalwar, S; Stone, R; 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Klabbers, P; Lanaro, A; Levine, A; Long, K; Loveless, R; Mohapatra, A; Ojalvo, I; Perry, T; Pierro, G A; Polese, G; Ruggles, T; Sarangi, T; Savin, A; Sharma, A; Smith, N; Smith, W H; Taylor, D; Verwilligen, P; Woods, N; Collaboration, Authorinst The Cms

2016-01-01

A search for narrow resonances decaying to an electron and a muon is presented. The [Formula: see text] [Formula: see text] mass spectrum is also investigated for non-resonant contributions from the production of quantum black holes (QBHs). The analysis is performed using data corresponding to an integrated luminosity of 19.7[Formula: see text] collected in proton-proton collisions at a centre-of-mass energy of 8[Formula: see text] with the CMS detector at the LHC. With no evidence for physics beyond the standard model in the invariant mass spectrum of selected [Formula: see text] pairs, upper limits are set at 95 [Formula: see text] confidence level on the product of cross section and branching fraction for signals arising in theories with charged lepton flavour violation. In the search for narrow resonances, the resonant production of a [Formula: see text] sneutrino in R-parity violating supersymmetry is considered. The [Formula: see text] sneutrino is excluded for masses below 1.28[Formula: see text] for couplings [Formula: see text], and below 2.30[Formula: see text] for [Formula: see text] and [Formula: see text]. These are the most stringent limits to date from direct searches at high-energy colliders. In addition, the resonance searches are interpreted in terms of a model with heavy partners of the [Formula: see text] boson and the photon. In a framework of TeV-scale quantum gravity based on a renormalization of Newton's constant, the search for non-resonant contributions to the [Formula: see text] [Formula: see text] mass spectrum excludes QBH production below a threshold mass [Formula: see text] of 1.99[Formula: see text]. In models that invoke extra dimensions, the bounds range from 2.36[Formula: see text] for one extra dimension to 3.63[Formula: see text] for six extra dimensions. This is the first search for QBHs decaying into the [Formula: see text] [Formula: see text] final state.

See This Sound

DEFF Research Database (Denmark)

Kristensen, Thomas Bjørnsten

2009-01-01

Anmeldelse af udstillingen See This Sound på Lentos Kunstmuseum Linz, Østrig, som markerer den foreløbige kulmination på et samarbejde mellem Lentos Kunstmuseum og Ludwig Boltzmann Institute Media.Art.Research. Udover den konkrete udstilling er samarbejdet tænkt som en ambitiøs, tværfaglig...

Raadioteatril elu sees. Elu sees? / Mart Aas, Tõnis Leemets ; interv. Kutt Kommel

Index Scriptorium Estoniae

Aas, Mart

2007-01-01

Eesti Raadio raadioteatri 78. sünnipäeval esietendus Vikerraadios dokumentaalkuuldemäng "Elu sees" Aleksander Alleni (hilisema nimega Aleksander Aas) mälestuste põhjal. Theatrumi lavastuse on raadiole seadnud Mart Aas, Marius Peterson, Toomas Lõhmuste ja Tõnis Leemets

Prospecção de fungos em ambientes e alimentos de psitacídeos do Parque Zoológico de Dois Irmãos, Recife - PE

OpenAIRE

Lima, Adriana Nunes de

2005-01-01

Para detecção de fungos foram analisadas amostras de solo, água e de ração de recintos de Psitacídeos do parque Zoológico de Dois Irmãos, Recife, PE. Foram realizadas quatro coletas, duas nos meses de fevereiro -março correspondendo ao verão, entretanto com precipitação atípica em 2004 e duas nos meses de maio - junho, correspondendo ao inverno da região Nordeste; foram coletadas 320 amostras, sendo 120 de solo, 124 de água e 76 de ração. As amostras foram especificadas da segu...

U.S. Air Force Information Resources Management: An Exploratory Study of Policy

National Research Council Canada - National Science Library

Munoz, Brian

1998-01-01

.... Information Resources Management (IRM) was established within the Department of Defense (DoD) in 1983 as a tool for better managing its information in the wake of automated information processing and sharing...

Seeing Both Sides

Science.gov (United States)

Coleman, Toni

2012-01-01

For many development officers, giving to their alma maters, employers, or local nonprofit agencies makes them better at their jobs by deepening their understanding of donor motivations and reinforcing what to do--and what not to do. Some can testify to the importance of stewardship because they weren't treated well. Others find that seeing their…

29 CFR 1917.152 - Welding, cutting and heating (hot work) 12 (See also § 1917.2, definition of Hazardous cargo...

Science.gov (United States)

2010-07-01

... 29 Labor 7 2010-07-01 2010-07-01 false Welding, cutting and heating (hot work) 12 (See also Â..., DEPARTMENT OF LABOR (CONTINUED) MARINE TERMINALS Related Terminal Operations and Equipment § 1917.152 Welding... Captain of the Port if welding or other hot work is to be carried out at a facility where dangerous...

Discovery Mondays - 'Particle tracks: Seeing the invisible'

CERN Multimedia

2007-01-01

Simulation of particle tracks in the CMS detector. How can you 'see' something as infinitesimal and fleeting as an elementary particle that defeats even the most powerful microscope? Well, physicists have detectors to snoop on them. Unlike biologists looking at bacteria, physicists don't see the particles themselves. They study their impact on sensitive materials as they pass through them at ultra high speed, a bit like seeing plane vapour trails in a clear sky. At the next Discovery Monday you will be able to find out about the different methods used at CERN to detect particles. There will be demonstrations of the cloud chamber, where particles leave tell-tale evidence of their passage in tracks of droplets. You will also learn about past and current particle track detection techniques and how the tracks are reconstructed into magnificent composite images. Don't miss this opportunity to learn about the various ways of 'seeing' particles. The event will be conducted in French. Come along to the Microcosm ...

Fundamental and applied aspects of astronomical seeing

International Nuclear Information System (INIS)

Coulman, C.E.

1985-01-01

It is pointed out that despite recent advances in the use of spacecraft as observatory platforms, much astronomy is still conducted from the surface of the earth. The literature on astronomical seeing and observatory site selection is widely scattered throughout journals and conference reports concerned with various disciplines. This survey has the objective to represent the state of the subject up to 1982. A description of the history and prospects of the considered subject is presented, and the optics of seeing are examined. The meteorology of seeing is discussed, taking into account aspects of micrometeorology and small-scale turbulence near the surface, the diurnal cycle in the planetary boundary layer, the temperature structure above the planetary boundary layer, and the effects of terrain. Attention is given to the calculation of system performance from microthermal data, optical methods for the measurement of seeing, and techniques for minimizing image-degrading effects of the atmosphere. 279 references

Hydrogen Isotope Measurements of Organic Acids and Alcohols by Pyrolysis-GC-MS-TC-IRMS

Science.gov (United States)

Socki, Richard A.; Fu, Qi; Niles, Paul B.

2011-01-01

One possible process responsible for methane generation on Mars is abiotic formation by Fischer-Tropsch-type (FTT) synthesis during serpentinization reactions. Measurement of carbon and hydrogen isotopes of intermediary organic compounds can help constrain the origin of this methane by tracing the geochemical pathway during formation. Of particular interest within the context of this work is the isotopic composition of organic intermediaries produced on the surfaces of mineral catalysts (i.e. magnetite) during hydrothermal experiments, and the ability to make meaningful and reproducible hydrogen isotope measurements. Reported here are results of experiments to characterize the hydrogen isotope composition of low molecular weight organic acids and alcohols. The presence of these organic compounds has been suggested by others as intermeadiary products made during mineral surface catalyzed reactions. This work compliments our previous study characterizing the carbon isotope composition of similar low molecular weight intermediary organic compounds (Socki, et al, American Geophysical Union Fall meeting, Abstr. #V51B-2189, Dec., 2010). Our hydrogen isotope measurements utilize a unique analytical technique combining Pyrolysis-Gas Chromatograph-Mass Spectrometry-High Temperature Conversion-Isotope Ratio Mass Spectrometry (Py-GC-MS-TC-IRMS). Our technique is unique in that it carries a split of the pyrolyzed GC-separated product to a Thermo DSQ-II? quadrupole mass spectrometer as a means of making qualitative and semi-quantitative compositional measurements of separated organic compounds, therefore both chemical and isotopic measurements can be carried out simultaneously on the same sample.

A precise measurement of the [Formula: see text] meson oscillation frequency.

Science.gov (United States)

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2016-01-01

The oscillation frequency, [Formula: see text], of [Formula: see text] mesons is measured using semileptonic decays with a [Formula: see text] or [Formula: see text] meson in the final state. The data sample corresponds to 3.0[Formula: see text] of pp collisions, collected by the LHCb experiment at centre-of-mass energies [Formula: see text] = 7 and 8[Formula: see text]. A combination of the two decay modes gives [Formula: see text], where the first uncertainty is statistical and the second is systematic. This is the most precise single measurement of this parameter. It is consistent with the current world average and has similar precision.

Osteoartropatia hipertrófica primária (paquidermoperiostose: relato de casos em dois irmãos Primary hypertrophic osteoarthropathy (pachydermoperiostosis: case report of two sibling

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Tarcísio Nunes Carvalho

2004-04-01

Full Text Available Neste artigo apresentamos dois irmãos acometidos pela osteoartropatia hipertrófica primária (paquidermoperiostose. Esta representa somente 3% a 5% de todos os casos de osteoartropatia hipertrófica. Nos nossos pacientes as alterações nos ossos longos são evidenciadas em radiografias convencionais, constando-se em neoformação óssea periosteal e alargamento das diáfises.We report a case of two siblings with primary hypertrophic osteoarthropathy (pachydermoperiostosis. Pachydermoperiostosis represents only 3 to 5 per cent of all cases of hypertrophic osteoarthropathy. These patients presented long bone changes on conventional x-ray films including periosteal new bone formation and expansion of the diaphysis.

Use of Proton SEE Data as a Proxy for Bounding Heavy-Ion SEE Susceptibility

Science.gov (United States)

Ladbury, Raymond L.; Lauenstein, Jean-Marie; Hayes, Kathryn P.

2015-01-01

Although heavy-ion single-event effects (SEE) pose serious threats to semiconductor devices in space, many missions face difficulties testing such devices at heavy-ion accelerators. Low-cost missions often find such testing too costly. Even well funded missions face issues testing commercial off the shelf (COTS) due to packaging and integration. Some missions wish to fly COTS systems with little insight into their components. Heavy-ion testing such parts and systems requires access to expensive and hard-to-access ultra-high energy ion accelerators, or significant system modification. To avoid these problems, some have proposed using recoil ions from high-energy protons as a proxy to bound heavy-ion SEE rates.

Measurement of charged particle multiplicities and densities in [Formula: see text] collisions at [Formula: see text]TeV in the forward region.

Science.gov (United States)

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Charged particle multiplicities are studied in proton-proton collisions in the forward region at a centre-of-mass energy of [Formula: see text]TeV with data collected by the LHCb detector. The forward spectrometer allows access to a kinematic range of [Formula: see text] in pseudorapidity, momenta greater than [Formula: see text] and transverse momenta greater than [Formula: see text]. The measurements are performed using events with at least one charged particle in the kinematic acceptance. The results are presented as functions of pseudorapidity and transverse momentum and are compared to predictions from several Monte Carlo event generators.

Seeing is believing

Science.gov (United States)

Steve Wingate; David Wolf

1997-01-01

When people view forest management activities there is usually nobody present to explain or interpret what is actually taking place. They judge what has happened by what they can see. In the short term, many long-term, beneficial activities such as clearcuts or herbicide applications appear to the average person as destruction, and they often only view an activity at...

Dual Si and O Isotope Measurement of Lunar Samples Using IRMS

Science.gov (United States)

Banerjee, N.; Hill, P. J. A.; Osinski, G. R.

2016-12-01

The use of isotopic systems and their associated theoretical models have become an increasingly sophisticated tool for investigating the origin of planetary bodies in the solar system. It was originally hypothesized that evidence for the impact origin of Moon would manifest itself as an isotopic heterogeneity between lunar and terrestrial samples; however, most isotope systems show no difference between the bulk Earth and Moon. The stable isotopes of both silicon (Si) and oxygen (O) have been essential in further understanding planetary processes including core formation. Historically the analysis of the Si and O isotope ratios in terrestrial and extraterrestrial material has primarily been measured independent of each other through three main techniques: isotope ratio mass spectrometry (IRMS), secondary ion mass spectrometry (SIMS), and multi-collector inductively coupled plasma mass-spectrometry (MC-ICPMS). Each technique has its own strength and weakness in regards to resolution and precision; however, one of the main limiting factors in all three of these techniques rests on the requirement of multiple aliquots. As most literature focuses on the measurement of oxygen or silicon isotopes, this unique line allows for the precise analysis of Si and O isotopes from the same aliquot of bulk sample, which cannot be done with SIMS or ICP-MS analysis. To deal with this problem a unique laser line system has been developed in the Laboratory for Stable Isotope Science at Western University, Canada, that simultaneously extracts SiF4 and O2 from the same 1-2 mg aliquot. We present the application of analyzing both isotopic systems from the sample aliquot to Apollo, meteoritic, and terrestrial samples and its implication for the formation of the Moon. Preliminary results from this line suggest that although the O isotopes ratios are consistent with a homogenous Moon-Earth system, a difference is observed in Si isotopes between Apollo and terrestrial samples compared to

IT Workforce: Key Practices Help Ensure Strong Integrated Program Teams; Selected Departments Need to Assess Skill Gaps

Science.gov (United States)

2016-11-01

principles and steps associated with workforce planning that agencies can utilize in their efforts to assess and address IT skill gaps. See GAO-04-39...As another example, our prior review of the United States Department of Agriculture’s Farm Service Agency’s Modernize and Innovate the Delivery of...IT WORKFORCE Key Practices Help Ensure Strong Integrated Program Teams; Selected Departments Need to Assess Skill Gaps

The Holy See and the NPT

International Nuclear Information System (INIS)

1972-01-01

The agreement between the Holy See and the International Atomic Energy Agency for the application of safeguards in connection with the Treaty on the Non-Proliferation of Nuclear Weapons was signed in Vienna on 26 June 1972. The preamble to the agreement states that the Holy See 'enjoys exclusive sovereignty and jurisdiction over the Vatican City State, of which the Roman Pontiff is the sovereign'. The Vatican City State, which covers a very small area, is itself 'ever and in all cases a neutral and inviolable territory', and since 18 June 1960 the whole of the Vatican City has been included in the Register of Cultural Property under Special Protection in the Event of Armed Conflict, which is deposited with the United Nations Educational, Scientific and Cultural Organization, and it has the rights and obligations which follow from its relations with third States. The Vatican City State is thus strictly adhering to the spirit of neutrality which characterizes the policy and action of the Holy See in the international community. Nevertheless, as pointed out by Monseigneur Oriano Quilici, Resident Representative of the Holy See to the Agency, 'this by no means implies that the Vatican City State cannot accept the controls and safeguards provided for under Article III of the Treaty on the Non-Proliferation of Nuclear Weapons in respect of all contracting parties'. (author)

Hydrogen (H) Isotope Composition of Type II Kerogen Extracted by Pyrolysis-GC-MS-IRMS: Terrestrial Shale Deposits as Martian Analogs

Science.gov (United States)

Socki, Richard A.; Pernia, Denet; Evans, Michael; Fu, Qi; Bissada, Kadry K.; Curiale, Joseph A.; Niles, Paul B.

2014-01-01

Described here is a technique for H isotope analysis of organic compounds pyrolyzed from kerogens isolated from gas- and liquids-rich shales. Application of this technique will progress the understanding of the use of H isotopes not only in potential kerogen occurrences on Mars, but also in terrestrial oil and gas resource plays. H isotope extraction and analyses were carried out utilizing a CDS 5000 Pyroprobe connected to a Thermo Trace GC interfaced with a Thermo MAT 253 IRMS. Also, a split of GC-separated products was sent to a DSQ II quadrupole MS to make qualitative and semi-quantitative compositional measurements of these products. Kerogen samples from five different basins (type II and II-S) were dehydrated (heated to 80 C overnight under vacuum) and analyzed for their H isotope compositions by Pyrolysis-GC-MS-TC-IRMS. This technique takes pyrolysis products separated via GC and reacts them in a high temperature conversion furnace (1450 C), which quantitatively forms H2. Samples ranging from 0.5 to 1.0mg in size, were pyrolyzed at 800 C for 30s. and separated on a Poraplot Q GC column. H isotope data from all kerogen samples typically show enrichment in D from low to high molecular weight. H2O average delta D = -215.2 per mille (V-SMOW), ranging from - 271.8 per mille for the Marcellus Shale to -51.9 per mille for a Polish shale. Higher molecular weight compounds like toluene (C7H8) have an average delta D of -89.7 per mille, ranging from -156.0 per mille for the Barnett Shale to -50.0 per mille for the Monterey Shale. We interpret these data as representative of potential H isotope exchange between hydrocarbons and sediment pore water during basin formation. Since hydrocarbon H isotopes readily exchange with water, these data may provide some useful information on gas-water or oil-water interaction in resource plays, and further as a possible indicator of paleoenvironmental conditions. Alternatively, our data may be an indication of H isotope exchange with

How community rehabilitation workers see their work

Directory of Open Access Journals (Sweden)

M. Petrick

2002-02-01

Full Text Available This paper reports on research conducted by theWits/Tintswalo Community Rehabilitation, Research and Education(CORRE Programme amongst qualified community rehabilitationworkers (CRWs. The aim was to understand how CRWs see  theirrole, successes, supervision support received, problems encounteredand possible solutions.Eighteen qualified CRWs completed a questionnaire, which contained a range of open-ended and semi-structured questions.The findings included their perceived role and successes in theirwork. They were satisfied with the supervision received from theirtherapy supervisors and support from their communities. TheDepartment of Health did not support them as much as did theircommunities. The lack of government assistance for transport wastheir biggest problem: They were not always able to reach  far awayclients and spent a lot of time travelling to and from clients everyday. They were also concerned that they were not registerable withthe South African Medical and Dental Council (SAMDC.   These findings provided the Northern Province and the CommunityBased Rehabilitation (CBR manager with information to improveCBR service delivery. A two year diploma course in therapy assistance (community for CRWs, occupational and physiotherapy assistants has been started.

Search for Higgs boson pair production in the [Formula: see text] final state from pp collisions at [Formula: see text] TeVwith the ATLAS detector.

Science.gov (United States)

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A search for Higgs boson pair production [Formula: see text] is performed with 19.5 fb[Formula: see text] of proton-proton collision data at [Formula: see text] TeV, which were recorded by the ATLAS detector at the Large Hadron Collider in 2012. The decay products of each Higgs boson are reconstructed as a high-momentum [Formula: see text] system with either a pair of small-radius jets or a single large-radius jet, the latter exploiting jet substructure techniques and associated b -tagged track-jets. No evidence for resonant or non-resonant Higgs boson pair production is observed. The data are interpreted in the context of the Randall-Sundrum model with a warped extra dimension as well as the two-Higgs-doublet model. An upper limit on the cross-section for [Formula: see text] of 3.2 (2.3) fb is set for a Kaluza-Klein graviton [Formula: see text] mass of 1.0 (1.5) TeV, at the 95 % confidence level. The search for non-resonant Standard Model hh production sets an observed 95 % confidence level upper limit on the production cross-section [Formula: see text] of 202 fb, compared to a Standard Model prediction of [Formula: see text] fb.

Atrofia muscular proximal neurogenica hereditaria (doença de Wohlfart-Kugelberg-Welander: estudo clinico, eletromiografico e anatomo-patologico de 3 irmãos

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Marcos R. G. de Freitas

1976-03-01

Full Text Available Os autores relatam os casos de três irmãos com fraqueza e amiotrofia proximal dos membros de início na infância. Os estudos eletromiográficos e de biópsias musculares revelaram alterações do tipo neurogênico de permeio com alterações miogênicas. Fazem consideração sobre esta singular associação, considerando as alterações do tipo miopático como secundárias à denervação de longa duração. O estudo histopatológico medular, em um dos pacientes, revelou degeneração das células motoras das pontas anteriores, constituindo, assim, o 4.° estudo de autópsia da doença de Wohlfart-Kugelberg-Welander, na literatura.

MODY, a história de dois irmãos...porque o raro também acontece!

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Andreia Filipa Miranda Mota

2017-09-01

Full Text Available Maturity Onset Diabetes of the Young (MODY é um tipo de diabetes mellitus não insulino-dependente, sem insulinorresistência ou disfunção autoimune das células β pancreáticas. Apresenta história familiar e início antes dos 25 anos. Prevalência estimada de 1-4% dos doentes diabéticos pediátricos. Apresenta-se o caso clínico de um rapaz, previamente saudável, cuja clínica de hiperglicemia em jejum fez diagnóstico inicial de diabetes mellitus tipo 1. Após conhecimento do diagnóstico de MODY na irmã da linhagem materna, não convivente, procedeu-se ao estudo genético, tendo-se identificado uma mutação em heterozigotia no gene GCK. A elevada suspeição clínica, habitualmente suportada pela história familiar sugestiva, é o primeiro passo para o correto diagnóstico. No entanto, a necessidade de exames complementares dispendiosos e morosos e a sua prevalência dificultam o seu diagnóstico, impossibilitando desde o início a otimização da terapêutica e do prognóstico, bem como o aconselhamento genético.

GC-C-IRMS analysis of FAMEs as a tool to ascertain the diet of Iberian pigs used for the production of pork products with high added value

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Raposo, C.

2013-04-01

Full Text Available Taste, quality and perceived health benefits result in a high demand for both green and mature pork products derived from the Iberian bred swine. These characteristics are directly related to diet and breeding style (free ranging in a particular Mediterranean ecosystem: the Dehesa. Given that current demand is not matched by the available resources, animal feed is increasingly used. GC-C-IRMS analysis of Palmitic, Stearic, Oleic and Linoleic Acid methyl esters allows for differentiating between pork raised in the traditional way and that fattened on animal feed. Although a value of δ13CC18:1 = –25.9‰ is a good discriminator, exploratory analysis of principal canonical components is required to properly assign any unknown sample.El sabor, la calidad y los efectos saludables de los derivados del cerdo ibérico dan lugar a una elevada demanda de los mismos, tanto en fresco como curados. Las características mencionadas responden a una dieta y crianza específicas (libres en la Dehesa, alimentándose de lo que ésta produce. Frecuentemente, los recursos disponibles son insuficientes para cubrir la demanda, dando en ocasiones lugar a la alimentación artificial de algunos de los cerdos. El análisis de las relaciones isotópicas 13C/12C de los ácidos grasos Palmítico, Esteárico, Oleico y Linoleico mediante GC-C-IRMS permite diferenciar entre animales criados al estilo tradicional (acabados en montanera y aquellos alimentados con piensos. El valor de δ13CC18:1 = –25.9‰ es un buen indicador, pero la correcta asignación de una muestra dada requiere el empleo de los cuatro ácidos grasos indicados y su tratamiento estadístico mediante análisis de componentes principales.

Wait times in the emergency department for patients with mental illness

Science.gov (United States)

Atzema, Clare L.; Schull, Michael J.; Kurdyak, Paul; Menezes, Natasja M.; Wilton, Andrew S.; Vermuelen, Marian J.; Austin, Peter C.

2012-01-01

Background: It has been suggested that patients with mental illness wait longer for care than other patients in the emergency department. We determined wait times for patients with and without mental health diagnoses during crowded and noncrowded periods in the emergency department. Methods: We conducted a population-based retrospective cohort analysis of adults seen in 155 emergency departments in Ontario between April 2007 and March 2009. We compared wait times and triage scores for patients with mental illness to those for all other patients who presented to the emergency department during the study period. Results: The patients with mental illness (n = 51 381) received higher priority triage scores than other patients, regardless of crowding. The time to assessment by a physician was longer overall for patients with mental illness than for other patients (median 82, interquartile range [IQR] 41–147 min v. median 75 [IQR 36–140] min; p < 0.001). The median time from the decision to admit the patient to hospital to ward transfer was markedly shorter for patients with mental illness than for other patients (median 74 [IQR 15–215] min v. median 152 [IQR 45–605] min; p < 0.001). After adjustment for other variables, patients with mental illness waited 10 minutes longer to see a physician compared with other patients during noncrowded periods (95% confidence interval [CI] 8 to 11), but they waited significantly less time than other patients as crowding increased (mild crowding: −14 [95% CI −12 to −15] min; moderate crowding: −38 [95% CI −35 to −42] min; severe crowding: −48 [95% CI −39 to −56] min; p < 0.001). Interpretation: Patients with mental illness were triaged appropriately in Ontario’s emergency departments. These patients waited less time than other patients to see a physician under crowded conditions and only slightly longer under noncrowded conditions. PMID:23148052

Seeing-off of dead bodies at death discharges in Japan.

Science.gov (United States)

Masaki, Sakiko; Asai, Atsushi

2013-12-01

For most death discharge ('shibou tai-in') patients, hospitals in Japan offer seeing-off ('omiokuri') services, a practice characteristic of Japanese culture. When a patient dies, nurses usually perform after-death procedures before transferring the body to the mortuary, where the nurses and doctors gather to provide the seeing-off service. This study was carried out to determine differences between the nurses' and bereaved families' opinions and thoughts regarding the seeing-off service. Semi-structured interviews were conducted with 17 nurses (focus group interviews) and 6 bereaved families (personal interviews). The interviews assessed: (1) the reasons why nurses provided seeing-off services; (2) thoughts during the seeing-off service; (3) impressions of the mortuary rituals; and (4) the necessity for the seeing-off service. The results indicated that nurses expressed their courtesy and sense of appreciation during the seeing-off service, which was recognised as an important nursing role. In contrast, bereaved families felt thankful but also doubtful, particularly as regards the mortuary rituals. In light of the differences in perspective between nurses and families, it may be that the level of satisfaction with the seeing-off service is largely affected by the relationship between the family and the medical professionals before the patient's death. Our study also notes that Japanese people respect the dead body and treat it with care, reflecting the unique culture and customs of Japan.

Will we still see SEEs?

International Nuclear Information System (INIS)

Calviani, M.; Brugger, M.; Losito, R.; Spiezia, G.; King, Q.; Thurel, Y.

2012-01-01

The actions taken during the first years of the Radiation to Electronics (R2E) Mitigation Project has allowed a drastic reduction of the rate of Single Event Errors (SEEs) on radiation-sensitive electronic equipment installed in the LHC underground areas. Shielding and relocation activities, performed during the first Long Shutdown (LS1) in 2013/2014, will allow the resolution of the present issues concerning UJs of Points 1, 5, 7 and the cavern of Point 8. The parallel development of radiation tolerant power converters will address the remaining concerns for equipment in the RRs. Similarly research works on super-conducting links will address the relocation of equipment away from RRs and further exposed UJs. Radiation levels in areas where luminosity is the source are under control. The questions yet remaining are related to the evolution of the beam-gas source term in the arc and dispersion suppressor region, and to the evolution of losses at the betatron and momentum insertion regions. 2012 operation will enable these points to be investigated; this will be used for a complete forecast of radiation levels and projected failures after operation is resumed in 2014-15. (authors)

The Holy See accedes

International Nuclear Information System (INIS)

1971-01-01

On 25 February the Holy See became the sixty-third non-nuclear weapon State to accede to or ratify the Treaty on the Non-Proliferation of Nuclear Weapons, when its representatives deposited instruments of accession in Moscow, London and Washington, the capitals of the three Depositary Governments for the Treaty. (author)

Seeing With the Ears

NARCIS (Netherlands)

Koenderink, Jan

2015-01-01

In recent talks, I mentioned how my artist friends often complain that their clients see with their ears. It recently dawned on me that nobody understood what I said, or—worse—got the wrong idea. The audience thinks of bionic devices (Proulx, Stoerig, Ludowig, & Knoll, 2008) or bat echo location

To See and To Be Seen

DEFF Research Database (Denmark)

Nielsen, Kirsten

2013-01-01

autoritært gudsbillede, der kan medføre vold i Guds navn, går fejl af Gen 22's centrale budskab: afvisningen af menneskeofringer er udtryk for Guds omsorg. The aim of this article is to demonstrate: 1) that the root ראה plays a crucial role in Gen 16 and 22, where Hagar and Abraham see and acknowledge Yahweh......, and Yahweh sees and shows solicitude; 2) that there is a close connection between Yahweh as ‘he who sees and he who is seen’, i.e. between his solicitude and his appearance, as expressed in the names for God and places in Gen 16:13-14 and Gen 22:14; 3) that there is a link between Yahweh’s appearance, his...... holy places, and his double promise; 4) that Gen 16 and 22 are variants of the same narrative with the same theological point, namely: Yahweh’s solicitude; and 5) that the theological criticism of God in Gen 22 as an authoritarian being whose will may lead to violence being committed in his name...

Qualitative risk assessment for 100-DR-1 source operable unit

International Nuclear Information System (INIS)

Naiknimbalkar, N.M.

1994-01-01

The Washington State Department of Ecology (Ecology), the US Environmental Protection Agency (EPA), and the US Department of Energy (DOE), signatories to the Hanford Federal Facility Agreement and Consent Order have developed the Hanford site Past-Practice Strategy to emphasize initiating and completing waste site cleanups with a bias for action. This strategy relies, in part, upon the use of a qualitative risk assessment (QRA) to assist in decision-making. The QRA is performed using the Hanford Site Baseline Risk Assessment Methodology (HSBRAM) as guidance (DOE-RL 1993a). The results will be used, along with other considerations, to make a recommendation for or against an interim remedial measure (IRM) at each high-priority waste site. The objective of conducting IRMs at Hanford, is to achieve cleanup and reduce risk in the shortest time possible and in a cost effective manner

IRM: A Look Backward and Forward at the Federal Level.

Science.gov (United States)

Caudle, Sharon L.

1988-01-01

Describes a study of information resources management in federal, cabinet level executive, and military departments. The topics discussed include typical department organizations, the impact of the paperwork reduction act, administrative goals, major influences on information resources management, and a comparison of management challenges across…

Comprehensive authentication of (E)-alpha(beta)-ionone from raspberries, using constant flow MDGC-C/P-IRMS and enantio-MDGC-MS.

Science.gov (United States)

Sewenig, Sabine; Bullinger, Dino; Hener, Uwe; Mosandl, Armin

2005-02-23

A new coupling system of GC-GC, connected via a Multi Column Switching Device MCS2 for measuring isotope ratios, is introduced. By means of several standard substances the precise and accurate measurement of isotopic values is proved. First applications concerning the authentication of raspberry aroma compounds are established. Consequently, the combination of constant flow multidimensional gas chromatography-combustion/pyrolysis-isotope ratio mass spectrometry (MDGC-C/P-IRMS) is applied to the authenticity assessment of (E)-alpha(beta)-ionone from six different raspberry cultivars. Furthermore, 12 commercially available raspberry products and samples of (E)-alpha(beta)-ionone, some declared to be natural, are investigated. delta(2)Eta(V)(-)(SMOW) and delta(13)C(V)(-)(PDB) values of (E)-alpha(beta)-ionone are determined, and characteristic authenticity ranges were concluded from raspberries by correlation of both delta(2)Eta(V)(-)(SMOW) and delta(13)C( V)(-)(PDB) values. The results are correlated with the determination of enantiomeric purities of (E)-alpha-ionone, using stir bar sorptive extraction enantio-multidimensional gas chromatography mass spectrometry (SBSE-enantio-MDGC-MS).

Mass Spectrometric Investigation of Silicon Extremely Enriched in (28)Si: From (28)SiF4 (Gas Phase IRMS) to (28)Si Crystals (MC-ICP-MS).

Science.gov (United States)

Pramann, Axel; Rienitz, Olaf

2016-06-07

A new generation of silicon crystals even further enriched in (28)Si (x((28)Si) > 0.999 98 mol/mol), recently produced by companies and institutes in Russia within the framework of a project initiated by PTB, were investigated with respect to their isotopic composition and molar mass M(Si). A modified isotope dilution mass spectrometric (IDMS) method treating the silicon as the matrix containing a so-called virtual element (VE) existing of the isotopes (29)Si and (30)Si solely and high resolution multicollector inductively coupled plasma mass spectrometry (MC-ICP-MS) were applied in combination. This method succeeds also when examining the new materials holding merely trace amounts of (29)Si (x((29)Si) ≈ 5 × 10(-6) mol/mol) and (30)Si (x((30)Si) ≈ 7 × 10(-7) mol/mol) extremely difficult to detect with lowest uncertainty. However, there is a need for validating the enrichment in (28)Si already in the precursor material of the final crystals, silicon tetrafluoride (SiF4) gas prior to crystal production. For that purpose, the isotopic composition of selected SiF4 samples was determined using a multicollector magnetic sector field gas-phase isotope ratio mass spectrometer. Contaminations of SiF4 by natural silicon due to storing and during the isotope ratio mass spectrometry (IRMS) measurements were observed and quantified. The respective MC-ICP-MS measurements of the corresponding crystal samples show-in contrast-several advantages compared to gas phase IRMS. M(Si) of the new crystals were determined to some extent with uncertainties urel(M) < 1 × 10(-9). This study presents a clear dependence of the uncertainty urel(M(Si)) on the degree of enrichment in (28)Si. This leads to a reduction of urel(M(Si)) during the past decade by almost 3 orders of magnitude and thus further reduces the uncertainty of the Avogadro constant NA which is one of the preconditions for the redefinition of the SI unit kilogram.

You can see galaxies from your computer | CTIO

Science.gov (United States)

Visitor's Computer Guidelines Network Connection Request Instruments Instruments by Telescope IR Instruments Logs Tololo Kaxis Webcam NOAO Newsletters NOAO Data Archive Astronomical Links Visitor's Computer ‹› You are here CTIO Home » You can see galaxies from your computer You can see galaxies from

Can you see Air?

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 12; Issue 6. Can you see Air? Andal Narayanan Joseph Samuel Supurna Sinha. Classroom Volume 12 Issue 6 June 2007 pp 71-75. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/012/06/0071-0075 ...

Authenticity assessment of gamma- and delta-decalactone from prunus fruits by gas chromatography combustion/pyrolysis isotope ratio mass spectrometry (GC-C/P-IRMS).

Science.gov (United States)

Tamura, Hirotoshi; Appel, Markus; Richling, Elke; Schreier, Peter

2005-06-29

Authenticity assessment of gamma-decalactone (1) and delta-decalactone (2) from peach (Prunus persica var. persica), apricot (Prunus armeniaca), and nectarine (Prunus persica var. nectarina) was performed using gas chromatography-isotope ratio mass spectrometry (GC-IRMS) in the combustion (C) and pyrolysis (P) mode. In addition, commercially available synthetic (nature-identical) 1 and 2 as well as biotechnologically produced samples (declared to be "natural") were characterized by their delta(2)H(V)(-)(SMOW) and delta(13)C(V)(-)(PDB) values. For the Prunus fruits under study, rather narrow ranges of delta(13)C(V)(-)(PDB) and delta(2)H(V)(-)(SMOW) data of 1, varying from - 34.6 per thousand to - 38.4 per thousand and -160 per thousand to -206 per thousand, respectively, were obtained. Synthetic references of 1 showed delta(13)C(V)(-)(PDB) and delta(2)H(V)(-)(SMOW) data ranging from -27.4 per thousand to -28.3 per thousand and -151 per thousand to -184 per thousand, respectively. Samples of 1 declared to be "natural" exhibited ranges from -28.1 per thousand to -29.2 per thousand and -192 per thousand to -286 per thousand for delta(13)C(V)(-)(PDB) and delta(2)H(V)(-)(SMOW), respectively. For 2 from peach, apricot, and nectarine, delta(13)C(V)(-)(PDB) values ranging from -34.0 per thousand to -37.9 per thousand were determined; the delta(2)H(V)(-)(SMOW) values ranged from -171 per thousand to -228 per thousand. The delta(13)C(V)(-)(PDB) and delta(2)H(V)(-)(SMOW) data for synthetic 2 were -28.2 per thousand and -171 per thousand, respectively, that is, similar to those of 2 from "natural" origin, ranging from -27.7 per thousand to -30.1 per thousand and -185 per thousand to -230 per thousand for delta(13)C(V)(-)(PDB) and delta(2)H(V)(-)(SMOW), respectively. GC-C/P-IRMS allowed clear-cut analytical differentiation of the synthetic and "ex-plant" origin of 1 and 2, whereas narrow ranges of delta(13)C(V)(-)(PDB) and delta(2)H(V)(-)(SMOW) data were found for samples of

20 CFR 661.110 - What is the role of the Department of Labor as the Federal governmental partner in the governance...

Science.gov (United States)

2010-04-01

... local governments. (b) The Department of Labor sees as one of its primary roles providing leadership and... provisions. State and local policies, interpretations, guidelines and definitions that are consistent with...

SEE - Sight Effectiveness Enhancement. Results of the automotive evaluation

DEFF Research Database (Denmark)

Andersen, V.; Hansen, K.D.; Cathala, T.

2006-01-01

In the SEE project two parallel evaluations have been conducted, an experimental trial of the automotive and another of the aeronautical application. The evaluations have measured the efficiency and HMI (human-machine interaction) characteristics of theSEE prototype. This report covers the automo......In the SEE project two parallel evaluations have been conducted, an experimental trial of the automotive and another of the aeronautical application. The evaluations have measured the efficiency and HMI (human-machine interaction) characteristics of theSEE prototype. This report covers...... the automotive part of the evaluation. The evaluation of the automotive application was carried out in computer simulated environments and followed the general objectives of the evaluation described in ‘Definition of theEvaluation Plan’ . The field experiment discussed, however, was given up due to lack...

iSeeChange: Crowdsourced Climate Change Reporting

Science.gov (United States)

Drapkin, J. K.

2012-12-01

Directly engaging local communities about their climate change experiences has never been more important. As weather and climate become more unpredictable, these experiences provide a baseline for community decisions, developing adaptation strategies, and planning for the future. Typically, climate change is documented in a top-down fashion: a scientist has a question, makes observations, and publishes a study; in the best case scenario, a journalist reports on the results; if there's time, a local anecdote is sought to put the results in a familiar context. iSeeChange, a public media project funded by the Corporation for Public Broadcasting, reports local environmental change in reverse and turns community questions and conversations with scientists into reported stories that promote opportunities to learn about climate change's affects on the environment and daily life. iSeeChange engages residents of the North Fork Valley region of western Colorado in a multiplatform conversation with scientists about how they perceive their environment is changing through the course of a year - season to season. By bringing together public radio, a mobile reporting and cellular engagement strategy, and a custom crowdsourcing multimedia platform, iSeeChange provides a central access point to collect observations (texts, photographs, voice recordings, and video), organize conversations and interviews with scientists, and report stories online and on air. In this way, iSeeChange is building a dynamic crowdsourced reservoir of information that can increase awareness of environmental problems and potentially disseminate useful information about climate change and successful adaptation strategies. Ultimately, by understanding the community's information needs in a localized question-driven context, the iSeeChange platform presents opportunities for the science community to better understand the value of information and develop better ways to tailor information for communities to use

Optimization of on-line hydrogen stable isotope ratio measurements of halogen- and sulfur-bearing organic compounds using elemental analyzer–chromium/high-temperature conversion isotope ratio mass spectrometry (EA-Cr/HTC-IRMS)

Science.gov (United States)

Gehre, Matthias; Renpenning, Julian; Geilmann, Heike; Qi, Haiping; Coplen, Tyler B.; Kümmel, Steffen; Ivdra, Natalija; Brand, Willi A.; Schimmelmann, Arndt

2017-01-01

Rationale: Accurate hydrogen isotopic analysis of halogen- and sulfur-bearing organics has not been possible with traditional high-temperature conversion (HTC) because the formation of hydrogen-bearing reaction products other than molecular hydrogen (H2) is responsible for non-quantitative H2 yields and possible hydrogen isotopic fractionation. Our previously introduced, new chromium-based EA-Cr/HTC-IRMS (Elemental Analyzer–Chromium/High-Temperature Conversion Isotope Ratio Mass Spectrometry) technique focused primarily on nitrogen-bearing compounds. Several technical and analytical issues concerning halogen- and sulfur-bearing samples, however, remained unresolved and required further refinement of the reactor systems.

See laser testing at different temperatures

Directory of Open Access Journals (Sweden)

Alexander Anatolievich Novikov

2016-10-01

Full Text Available The main problem for laser SEE testing at different temperatures is to determine correlation between laser pulse energy and LET. In the first approximation, LET values with the same laser pulse energy and different temperatures are directly proportional to the absorption coefficient of laser light in a semiconductor. Use of tabulated values could lead to errors and absorption coefficient should be determined for each sensitive volume of device under test (DUT. Temperature dependence of absorption coefficient could be determined using ionization response of DUT in power supply circuit under local laser irradiation. Using this approach a satisfactory correlation of ion and laser SEE test result was observed.

IRM in the Federal Government: Opinions and Reflections.

Science.gov (United States)

Haney, Glenn P.

1989-01-01

Evaluates various aspects of federal information resources management and reviews technological changes within the Department of Agriculture to illustrate current issues and future trends in information resources management. Topics discussed include telecommunications and networking; distributed processing and field office automation; the role of…

Terapia de linguagem de irmãos com transtornos invasivos do desenvolvimento: estudo longitudinal Language therapy of brothers with pervasive developmental disorders: longitudinal study

Directory of Open Access Journals (Sweden)

Andréa Regina Nunes Misquiatti

2010-01-01

Full Text Available O objetivo deste trabalho foi descrever o processo de intervenção fonoaudiológica de dois irmãos com transtornos invasivos do desenvolvimento, por meio de um estudo longitudinal de caso clínico. Participaram dois irmãos, um de nove e outro de 11 anos de idade, ambos do gênero masculino, com autismo (Caso 1 e transtorno invasivo do desenvolvimento sem outra especificação (Caso 2. Como procedimento de coleta e análise de dados foi realizado um estudo longitudinal, por meio de acompanhamento dos casos ao longo de quatro anos de intervenção fonoaudiológica. Foram realizadas filmagens durante as sessões de terapia, análise documental de informações dos prontuários referentes à anamnese, avaliação e relatórios terapêuticos fonoaudiológicos, exames e avaliações multidisciplinares. Em ambos os casos houve melhora no contato visual, na interação social, no vocabulário e na brincadeira simbólica. No Caso 1 ocorreu aumento de 2,0 para 6,2 atos comunicativos por minuto, no Caso 2 de 3,5 para 8,0 atos e ambos demonstraram predominância do meio verbal e maior variedade de funções comunicativas. Outros fatores influenciaram estes resultados, como a deficiência intelectual, a dinâmica familiar, os conflitos no relacionamento entre os irmãos e o ambiente escolar em que estavam inseridos. Confirmou-se a relevância do fonoaudiólogo em intervenções nos transtornos invasivos do desenvolvimento, junto a equipes multidisciplinares, para a discussão diagnóstica e de condutas mais adequadas. Estudos longitudinais podem contribuir para uma análise mais detalhada e fidedigna de intervenções terapêuticas nesses casos, para esclarecer lacunas existentes na literatura e subsidiar a atuação do fonoaudiólogo clínico.The aim of this research was to describe the language intervention process of two brothers with pervasive developmental disorders, through a longitudinal clinical case study. Two brothers - one nine and the other 11

Measurements of the branching fractions of [Formula: see text] decays.

Science.gov (United States)

Aaij, R; Abellan Beteta, C; Adametz, A; Adeva, B; Adinolfi, M; Adrover, C; Affolder, A; Ajaltouni, Z; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amhis, Y; Anderlini, L; Anderson, J; Andreassen, R; Appleby, R B; Aquines Gutierrez, O; Archilli, F; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Bachmann, S; Back, J J; Baesso, C; Balagura, V; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Bauer, Th; Bay, A; Beddow, J; Bediaga, I; Belogurov, S; Belous, K; Belyaev, I; Ben-Haim, E; Benayoun, M; Bencivenni, G; Benson, S; Benton, J; Berezhnoy, A; Bernet, R; Bettler, M-O; van Beuzekom, M; Bien, A; Bifani, S; Bird, T; Bizzeti, A; Bjørnstad, P M; Blake, T; Blanc, F; Blanks, C; Blouw, J; Blusk, S; Bobrov, A; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Bowcock, T J V; Bowen, E; Bozzi, C; Brambach, T; van den Brand, J; Bressieux, J; Brett, D; Britsch, M; Britton, T; Brook, N H; Brown, H; Burducea, I; Bursche, A; Buytaert, J; Cadeddu, S; Callot, O; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carranza-Mejia, H; Carson, L; Carvalho Akiba, K; Casse, G; Cattaneo, M; Cauet, Ch; Charles, M; Charpentier, Ph; Chen, P; Chiapolini, N; Chrzaszcz, M; Ciba, K; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coca, C; Coco, V; Cogan, J; Cogneras, E; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coombes, M; Coquereau, S; Corti, G; Couturier, B; Cowan, G A; Craik, D; Cunliffe, S; Currie, R; D'Ambrosio, C; David, P; David, P N Y; De Bonis, I; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Silva, W; De Simone, P; Decamp, D; Deckenhoff, M; Degaudenzi, H; Del Buono, L; Deplano, C; Derkach, D; Deschamps, O; Dettori, F; Di Canto, A; Dickens, J; Dijkstra, H; Dogaru, M; Domingo Bonal, F; Donleavy, S; Dordei, F; Dosil Suárez, A; Dossett, D; Dovbnya, A; Dupertuis, F; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; van Eijk, D; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; El Rifai, I; Elsasser, Ch; Elsby, D; Falabella, A; Färber, C; Fardell, G; Farinelli, C; Farry, S; Fave, V; Ferguson, D; Fernandez Albor, V; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fitzpatrick, C; Fontana, M; Fontanelli, F; Forty, R; Francisco, O; Frank, M; Frei, C; Frosini, M; Furcas, S; Furfaro, E; Gallas Torreira, A; Galli, D; Gandelman, M; Gandini, P; Gao, Y; Garofoli, J; Garosi, P; Garra Tico, J; Garrido, L; Gaspar, C; Gauld, R; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gibson, V; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gordon, H; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Grünberg, O; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hall, S; Hampson, T; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; Harrison, P F; Hartmann, T; He, J; Heijne, V; Hennessy, K; Henrard, P; Hernando Morata, J A; van Herwijnen, E; Hicks, E; Hill, D; Hoballah, M; Hombach, C; Hopchev, P; Hulsbergen, W; Hunt, P; Huse, T; Hussain, N; Hutchcroft, D; Hynds, D; Iakovenko, V; Ilten, P; Jacobsson, R; Jaeger, A; Jans, E; Jansen, F; Jaton, P; Jing, F; John, M; Johnson, D; Jones, C R; Jost, B; Kaballo, M; Kandybei, S; Karacson, M; Karbach, T M; Kenyon, I R; Kerzel, U; Ketel, T; Keune, A; Khanji, B; Kochebina, O; Komarov, I; Koopman, R F; Koppenburg, P; Korolev, M; Kozlinskiy, A; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kucharczyk, M; Kudryavtsev, V; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanciotti, E; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J-P; Lefèvre, R; Leflat, A; Lefrançois, J; Leroy, O; Li, Y; Li Gioi, L; Liles, M; Lindner, R; Linn, C; Liu, B; Liu, G; von Loeben, J; Lopes, J H; Lopez Asamar, E; 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The branching fractions of the decay [Formula: see text] for different intermediate states are measured using data, corresponding to an integrated luminosity of 1.0 fb -1 , collected by the LHCb experiment. The total branching fraction, its charmless component [Formula: see text] and the branching fractions via the resonant [Formula: see text] states η c (1 S ) and ψ (2 S ) relative to the decay via a J / ψ intermediate state are [Formula: see text] Upper limits on the B + branching fractions into the η c (2 S ) meson and into the charmonium-like states X (3872) and X (3915) are also obtained.

Seeing What Children See: Enhancing Understanding of Outdoor Learning Experiences through Body-Worn Cameras

Science.gov (United States)

Lloyd, Amanda; Gray, Tonia; Truong, Son

2018-01-01

This study investigates innovative ways that outdoor educators can actively promote young participants' authentic voice in educational research and, in turn, increase our understanding of their worldview through accurately recording what children are seeing, hearing, doing, and touching when they are beyond our researcher's gaze. The study was…

Pişirme Öncesinde Hamurun Kısa Süre Bekletilmesinin Pandispanya Nitelikleri Üzerine Etkisi

Directory of Open Access Journals (Sweden)

Halef Dizlek

2015-02-01

Full Text Available Bu çalışmada, hazırlanan kek hamurunun fırına beklemeksizin (doğrudan konulmasının ve kısa süre (10 d bekletildikten sonra konulmasının pandispanya nitelikleri (hacim, gözenek yapısı, yumuşaklık, nem içeriği vb. üzerindeki etkileri araştırılmıştır. Bu amaçla, farklı bileşimlere sahip dört kabartma tozu kek hamurunda üç ayrı düzeyde (%0.25, %1.25 ve %2.25 kullanılmıştır. Araştırma sonucunda, pandispanya hamurunun pişirme öncesinde kısa süre bekletilmesinin denemede ele alınan 12 farklı pandispanya formülünde ürün özelliklerini çok sınırlı ölçüde olumsuz etkilediği, genel olarak önemli bir değişikliğe (gerilemeye yol açmadığı belirlenmiştir. Bu durumun, pandispanya hamurunun formülünde temel bileşen olarak bulunan yumurta ve yüzey aktif maddenin hamura stabil ve kuvvetli bir yapı kazandırmasından ileri geldiği düşünülmektedir.

Inclusive quarkonium production at forward rapidity in pp collisions at [Formula: see text]TeV.

Science.gov (United States)

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2016-01-01

We report on the inclusive production cross sections of [Formula: see text], [Formula: see text], [Formula: see text](1S), [Formula: see text](2S) and [Formula: see text](3S), measured at forward rapidity with the ALICE detector in [Formula: see text] collisions at a center-of-mass energy [Formula: see text] TeV. The analysis is based on data collected at the LHC and corresponds to an integrated luminosity of 1.23 pb[Formula: see text]. Quarkonia are reconstructed in the dimuon-decay channel. The differential production cross sections are measured as a function of the transverse momentum [Formula: see text] and rapidity y , over the [Formula: see text] ranges [Formula: see text] GeV/ c for [Formula: see text], [Formula: see text] GeV/ c for all other resonances, and for [Formula: see text]. The cross sections, integrated over [Formula: see text] and y , and assuming unpolarized quarkonia, are [Formula: see text] [Formula: see text]b, [Formula: see text] [Formula: see text]b, [Formula: see text] nb, [Formula: see text] nb and [Formula: see text] nb, where the first uncertainty is statistical and the second one is systematic. These values agree, within at most [Formula: see text], with measurements performed by the LHCb collaboration in the same rapidity range.

Seleção de progênies de meio-irmãos de cenoura baseada em características de sementes Selection of carrot progenies based on seed characteristics

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Jairo V. Vieira

2005-03-01

Full Text Available A menor germinação e emergência de plântulas em campo de cenoura obtida nas sementes de cultivares nacionais em relação às importadas, aumenta o custo de produção além de impossibilitar a otimização do estande final através do emprego de semeadeiras de precisão. Setenta e quatro progênies de meio-irmãos oriundas de uma população de cenoura tipo Brasília foram avaliadas quanto a germinação, vigor e peso de sementes com o objetivo de verificar a variabilidade e as relações genéticas entre os referidos caracteres. Evidenciou-se a existência de diferenças significativas entre as progênies de meio-irmãos em relação a todos os caracteres avaliados. Os altos valores de herdabilidade e variabilidade genética entre progênies para os caracteres avaliados sugerem que métodos de melhoramento simples combinados com métodos de seleção tendo por base a teoria de índice podem ser aplicados visando a melhoria da qualidade fisiológica das sementes de cenoura.Low seed germination and stand establishment of carrot seeds from Brazilian cultivars generally increase the production cost and impairs the use of precision seeders. Germination, vigor and seed weight of 74 progenies from a population of carrot cv. Brasilia were evaluated to verify the variability and the genetic relations among these three characteristics. Significant differences were observed among the progenies in relation to all characteristics. High values of heritability and genetic variability among progenies suggests that simple breeding methods combined with index selection methods may be applied during breeding programs in order to increase the physiological seed quality of carrot.

Measurement of azimuthal correlations of D mesons with charged particles in pp collisions at [Formula: see text] TeV and p-Pb collisions at [Formula: see text] TeV.

Science.gov (United States)

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2017-01-01

The azimuthal correlations of D mesons with charged particles were measured with the ALICE apparatus in pp collisions at [Formula: see text] and p-Pb collisions at [Formula: see text] at the Large Hadron Collider. [Formula: see text], [Formula: see text], and [Formula: see text] mesons and their charge conjugates with transverse momentum [Formula: see text] and rapidity in the nucleon-nucleon centre-of-mass system [Formula: see text] (pp collisions) and [Formula: see text] (p-Pb collisions) were correlated to charged particles with [Formula: see text]. The yield of charged particles in the correlation peak induced by the jet containing the D meson and the peak width are compatible within uncertainties in the two collision systems. The data are described within uncertainties by Monte-Carlo simulations based on PYTHIA, POWHEG, and EPOS 3 event generators.

Enhanced learning through scale models and see-thru visualization

International Nuclear Information System (INIS)

Kelley, M.D.

1987-01-01

The development of PowerSafety International's See-Thru Power Plant has provided the nuclear industry with a bridge that can span the gap between the part-task simulator and the full-scope, high-fidelity plant simulator. The principle behind the See-Thru Power Plant is to provide the use of sensory experience in nuclear training programs. The See-Thru Power Plant is a scaled down, fully functioning model of a commercial nuclear power plant, equipped with a primary system, secondary system, and control console. The major components are constructed of glass, thus permitting visual conceptualization of a working nuclear power plant

Measurement of double-differential cross sections for top quark pair production in pp collisions at [Formula: see text][Formula: see text] and impact on parton distribution functions.

Science.gov (United States)

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2017-01-01

Normalized double-differential cross sections for top quark pair ([Formula: see text]) production are measured in pp collisions at a centre-of-mass energy of 8[Formula: see text] with the CMS experiment at the LHC. The analyzed data correspond to an integrated luminosity of 19.7[Formula: see text]. The measurement is performed in the dilepton [Formula: see text] final state. The [Formula: see text] cross section is determined as a function of various pairs of observables characterizing the kinematics of the top quark and [Formula: see text] system. The data are compared to calculations using perturbative quantum chromodynamics at next-to-leading and approximate next-to-next-to-leading orders. They are also compared to predictions of Monte Carlo event generators that complement fixed-order computations with parton showers, hadronization, and multiple-parton interactions. Overall agreement is observed with the predictions, which is improved when the latest global sets of proton parton distribution functions are used. The inclusion of the measured [Formula: see text] cross sections in a fit of parametrized parton distribution functions is shown to have significant impact on the gluon distribution.

Spectral analysis software improves confidence in plant and soil water stable isotope analyses performed by isotope ratio infrared spectroscopy (IRIS).

Science.gov (United States)

West, A G; Goldsmith, G R; Matimati, I; Dawson, T E

2011-08-30

Previous studies have demonstrated the potential for large errors to occur when analyzing waters containing organic contaminants using isotope ratio infrared spectroscopy (IRIS). In an attempt to address this problem, IRIS manufacturers now provide post-processing spectral analysis software capable of identifying samples with the types of spectral interference that compromises their stable isotope analysis. Here we report two independent tests of this post-processing spectral analysis software on two IRIS systems, OA-ICOS (Los Gatos Research Inc.) and WS-CRDS (Picarro Inc.). Following a similar methodology to a previous study, we cryogenically extracted plant leaf water and soil water and measured the δ(2)H and δ(18)O values of identical samples by isotope ratio mass spectrometry (IRMS) and IRIS. As an additional test, we analyzed plant stem waters and tap waters by IRMS and IRIS in an independent laboratory. For all tests we assumed that the IRMS value represented the "true" value against which we could compare the stable isotope results from the IRIS methods. Samples showing significant deviations from the IRMS value (>2σ) were considered to be contaminated and representative of spectral interference in the IRIS measurement. Over the two studies, 83% of plant species were considered contaminated on OA-ICOS and 58% on WS-CRDS. Post-analysis, spectra were analyzed using the manufacturer's spectral analysis software, in order to see if the software correctly identified contaminated samples. In our tests the software performed well, identifying all the samples with major errors. However, some false negatives indicate that user evaluation and testing of the software are necessary. Repeat sampling of plants showed considerable variation in the discrepancies between IRIS and IRMS. As such, we recommend that spectral analysis of IRIS data must be incorporated into standard post-processing routines. Furthermore, we suggest that the results from spectral analysis be

Regional origin assignment of red wines from Valencia (Spain) by (2)H NMR and (13)C IRMS stable isotope analysis of fermentative ethanol.

Science.gov (United States)

Giménez-Miralles, J E; Salazar, D M; Solana, I

1999-07-01

The use of the stable hydrogen and carbon isotope ratios of fermentative ethanol as suitable environmental fingerprints for the regional origin identification of red wines from Valencia (Spain) has been explored. Monovarietal Vitis vinifera L. cvs. Bobal, Tempranillo, and Monastrell wines have been investigated by (2)H NMR and (13)C IRMS for the natural ranges of site-specific (2)H/(1)H ratios and global delta(13)C values of ethanol over three vintage years. Statistically significant interregional and interannual (2)H and (13)C abundance differences have been noticed, which are interpreted in terms of environmental and ecophysiological factors of isotope content variation. Multivariate discriminant analysis is shown to provide a convenient means for integration of the classifying information, high discriminating abilities being demonstrated for the (2)H and (13)C fingerprints of ethanol. Reasonable differentiation results are achieved at a microregional scale in terms of geographic provenance and even grapevine genotypic features.

The use of stimulated electron emission (SEE) in homeland security applications

Science.gov (United States)

Ing, H.; Andrews, H. R.; Facina, M.; Lee, W. T.; Niu, H. W.

2012-06-01

Certain insulating solids can store a fraction of the absorbed energy when irradiated by ionizing radiation. The stored energy can be released subsequently by heating or optical stimulation. As a result, light may be emitted through Thermoluminescence (TL) or Optically-Stimulated Luminescence (OSL) and electrons may be emitted through Thermally-Stimulated Electron Emission (TSEE) or Optically-Stimulated Electron Emission (OSEE). TL and OSL are widely used in current radiation dosimetry systems. However, despite considerable research effort during the early 1970s, SEE was not commonly adopted for dosimetry applications. One of the main reasons is that SEE is a surface phenomenon, while luminescence is a bulk phenomenon, making SEE more susceptible to humidity, absorption of gases, minor physical defects and handling, both before and after irradiation. Nevertheless, it has been recognized that SEE may be useful for homeland security applications in nuclear forensics, where dose accuracy is not the primary performance metric. In this research, we are investigating the use of SEE for nuclear forensic applications. Many common materials, both natural and man-made, exhibit the phenomenon, providing an opportunity to use the environment itself as an in-situ radiation detector. We have designed and constructed a unique prototype reader for conducting SEE measurements. We have demonstrated that the SEE measurements from a variety of materials are quantitatively reproducible and correlated to radiation exposure. Due to the broad applicability of SEE, significant additional studies are warranted to optimize this novel technique for nuclear forensic and other applications.

See-through 3D technology for augmented reality

Science.gov (United States)

Lee, Byoungho; Lee, Seungjae; Li, Gang; Jang, Changwon; Hong, Jong-Young

2017-06-01

Augmented reality is recently attracting a lot of attention as one of the most spotlighted next-generation technologies. In order to get toward realization of ideal augmented reality, we need to integrate 3D virtual information into real world. This integration should not be noticed by users blurring the boundary between the virtual and real worlds. Thus, ultimate device for augmented reality can reconstruct and superimpose 3D virtual information on the real world so that they are not distinguishable, which is referred to as see-through 3D technology. Here, we introduce our previous researches to combine see-through displays and 3D technologies using emerging optical combiners: holographic optical elements and index matched optical elements. Holographic optical elements are volume gratings that have angular and wavelength selectivity. Index matched optical elements are partially reflective elements using a compensation element for index matching. Using these optical combiners, we could implement see-through 3D displays based on typical methodologies including integral imaging, digital holographic displays, multi-layer displays, and retinal projection. Some of these methods are expected to be optimized and customized for head-mounted or wearable displays. We conclude with demonstration and analysis of fundamental researches for head-mounted see-through 3D displays.

A4 see-saw models and form dominance

International Nuclear Information System (INIS)

Chen, M-C; King, Stephen F.

2009-01-01

We introduce the idea of Form Dominance in the (type I) see-saw mechanism, according to which a particular right-handed neutrino mass eigenstate is associated with a particular physical neutrino mass eigenstate, leading to a form diagonalizable effective neutrino mass matrix. Form Dominance, which allows an arbitrary neutrino mass spectrum, may be regarded as a generalization of Constrained Sequential Dominance which only allows strongly hierarchical neutrino masses. We consider alternative implementations of the see-saw mechanism in minimal A 4 see-saw models and show that such models satisfy Form Dominance, leading to neutrino mass sum rules which predict closely spaced neutrino masses with a normal or inverted neutrino mass ordering. To avoid the partial cancellations inherent in such models we propose Natural Form Dominance, in which a different flavon is associated with each physical neutrino mass eigenstate.

Measurements of top-quark pair differential cross-sections in the [Formula: see text] channel in pp collisions at [Formula: see text] TeV using the ATLAS detector.

Science.gov (United States)

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2017-01-01

This article presents measurements of [Formula: see text] differential cross-sections in a fiducial phase-space region, using an integrated luminosity of 3.2 fb[Formula: see text] of proton-proton data at a centre-of-mass energy of [Formula: see text] TeV recorded by the ATLAS experiment at the LHC in 2015. Differential cross-sections are measured as a function of the transverse momentum and absolute rapidity of the top quark, and of the transverse momentum, absolute rapidity and invariant mass of the [Formula: see text] system. The [Formula: see text] events are selected by requiring one electron and one muon of opposite electric charge, and at least two jets, one of which must be tagged as containing a b -hadron. The measured differential cross-sections are compared to predictions of next-to-leading order generators matched to parton showers and the measurements are found to be consistent with all models within the experimental uncertainties with the exception of the Powheg-Box [Formula: see text] Herwig++ predictions, which differ significantly from the data in both the transverse momentum of the top quark and the mass of the [Formula: see text] system.

Sample preparation techniques for the determination of natural 15N/14N variations in amino acids by gas chromatography-combustion-isotope ratio mass spectrometry (GC-C-IRMS).

Science.gov (United States)

Hofmann, D; Gehre, M; Jung, K

2003-09-01

In order to identify natural nitrogen isotope variations of biologically important amino acids four derivatization reactions (t-butylmethylsilylation, esterification with subsequent trifluoroacetylation, acetylation and pivaloylation) were tested with standard mixtures of 17 proteinogenic amino acids and plant (moss) samples using GC-C-IRMS. The possible fractionation of the nitrogen isotopes, caused for instance by the formation of multiple reaction products, was investigated. For biological samples, the esterification of the amino acids with subsequent trifluoroacetylation is recommended for nitrogen isotope ratio analysis. A sample preparation technique is described for the isotope ratio mass spectrometric analysis of amino acids from the non-protein (NPN) fraction of terrestrial moss. 14N/15N ratios from moss (Scleropodium spec.) samples from different anthropogenically polluted areas were studied with respect to ecotoxicologal bioindication.

IRMS detection of testosterone manipulated with 13C labeled standards in human urine by removing the labeled 13C.

Science.gov (United States)

Wang, Jingzhu; Yang, Rui; Yang, Wenning; Liu, Xin; Xing, Yanyi; Xu, Youxuan

2014-12-10

Isotope ratio mass spectrometry (IRMS) is applied to confirm testosterone (T) abuse by determining the carbon isotope ratios (δ(13)C value). However, (13)C labeled standards can be used to control the δ(13)C value and produce manipulated T which cannot be detected by the current method. A method was explored to remove the (13)C labeled atom at C-3 from the molecule of androsterone (Andro), the metabolite of T in urine, to produce the resultant (A-nor-5α-androstane-2,17-dione, ANAD). The difference in δ(13)C values between Andro and ANAD (Δδ(13)CAndro-ANAD, ‰) would change significantly in case manipulated T is abused. Twenty-one volunteers administered T manipulated with different (13)C labeled standards. The collected urine samples were analyzed with the established method, and the maximum value of Δδ(13)CAndro-ANAD post ingestion ranged from 3.0‰ to 8.8‰. Based on the population reference, the cut-off value of Δδ(13)CAndro-ANAD for positive result was suggested as 1.2‰. The developed method could be used to detect T manipulated with 3-(13)C labeled standards. Copyright © 2014 Elsevier B.V. All rights reserved.

Measurement of δ13C values of soil amino acids by GC-C-IRMS using trimethylsilylation: a critical assessment.

Science.gov (United States)

Rubino, Mauro; Milin, Sylvie; D'Onofrio, Antonio; Signoret, Patrick; Hatté, Christine; Balesdent, Jérôme

2014-01-01

In this study, we evaluated trimethylsilyl (TMS) derivatives as derivatization reagents for the compound-specific stable carbon isotope analysis of soil amino acids by gas chromatography-combustion-isotope ratio mass spectrometry (GC-C-IRMS). We used non-proteinogenic amino acids to show that the extraction-derivatization-analysis procedure provides a reliable method to measure δ(13)C values of amino acids extracted from soil. However, we found a number of drawbacks that significantly increase the final total uncertainty. These include the following: production of multiple peaks for each amino acid, identified as di-, tri- and tetra-TMS derivatives; a number of TMS-carbon (TMS-C) atoms added lower than the stoichiometric one, possibly due to incomplete combustion; different TMS-C δ(13)C for di-, tri- and tetra-TMS derivatives. For soil samples, only four amino acids (leucine, valine, threonine and serine) provide reliable δ(13)C values with a total average uncertainty of 1.3 ‰. We conclude that trimethylsilyl derivatives are only suitable for determining the (13)C incorporation in amino acids within experiments using (13)C-labelled tracers but cannot be applied for amino acids with natural carbon isotope abundance until the drawbacks described here are overcome and the measured total uncertainty significantly decreased.

Ammonia IRMS-TPD study on the distribution of acid sites in mordenite.

Science.gov (United States)

Niwa, Miki; Suzuki, Katsuki; Katada, Naonobu; Kanougi, Tomonori; Atoguchi, Takashi

2005-10-13

Using an IRMS-TPD (temperature programmed desorption) of ammonia, we studied the nature, strength, crystallographic location, and distribution of acid sites of mordenite. In this method, infrared spectroscopy (IR) and mass spectroscopy (MS) work together to follow the thermal behavior of adsorbed and desorbed ammonia, respectively; therefore, adsorbed species were identified, and their thermal behavior was directly connected with the desorption of ammonia during an elevation of temperature. IR-measured TPD of the NH4(+) cation was similar to MS-measured TPD, thus showing the nature of Brønsted acidity. From the behavior of OH bands, it was found that the Brønsted acid sites consisted of two kinds of OH bands at high and low wavenumbers, ascribable to OH bands situated on 12- and 8-member rings (MR) of mordenite structure, respectively. The amount and strength of these Brønsted hydroxyls were measured quantitatively based on a theoretical equation using a curve fitting method. Up to ca. 30% of the exchange degree, NH4(+) was exchanged with Na+ on the 12-MR to arrive at saturation; therefore, in this region, the Brønsted acid site was situated on the large pore of 12-MR. The NH4(+) cation was then exchanged with Na+ on 8-MR, and finally exceeded the amount on 12-MR. In the 99% NH4-mordenite, Brønsted acid sites were located predominantly on the 8-MR more than on the 12-MR. Irrespective of the NH4(+) exchange degree, the strengths deltaH of Brønsted OH were 145 and 153 kJ mol(-1) on the 12- and 8-MR, respectively; that is, the strength of Brønsted acid site on the 8-MR was larger than that on the 12-MR. A density functional theory (DFT) calculation supported the difference in the strengths of the acid sites. Catalytic cracking activity of the Brønsted acid sites on the 8-MR declined rapidly, while that on the 12-MR was remarkably kept. The difference in strength and/or steric capacity may cause such a difference in the life of a catalyst.

Light Higgs from Scalar See-Saw in Technicolor

DEFF Research Database (Denmark)

Foadi, Roshan; Frandsen, Mads Toudal

2012-01-01

We consider a TeV scale see-saw mechanism leading to light scalar resonances in models with otherwise intrinsically heavy scalars. The mechanism can provide a 125 GeV technicolor Higgs in e.g. two-scale TC models......We consider a TeV scale see-saw mechanism leading to light scalar resonances in models with otherwise intrinsically heavy scalars. The mechanism can provide a 125 GeV technicolor Higgs in e.g. two-scale TC models...

Looked-but-failed-to-see-errors in traffic

DEFF Research Database (Denmark)

Herslund, Mai-Britt; Jørgensen, N O

2003-01-01

Danish studies of traffic accidents at priority intersections have shown a particular type of accidents. In these accidents a car driver supposed to give way has collided with a bicycle rider on the priority road. Often the involved car drivers have maintained that they did not see the bicycle...... looking in the direction where the other parties were but have not seen (i.e. perceived the presence of) the other road user. This paper describes two studies approaching this problem.One study is based on 10 self-reported near accidents. It does show that "looked-but-failed-to-see" events do occur...... until immediately before the collision even though the bicycle must have been clearly visible.Similar types of accidents have been the subject of studies elsewhere. In literature they are labelled "looked-but-failed-to-see", because it seems clear that in many cases the car drivers have actually been...

Seeing Baby Dwarf Galaxies

Science.gov (United States)

2009-01-01

[figure removed for brevity, see original site] [figure removed for brevity, see original site] [figure removed for brevity, see original site] Visible/DSS Click on image for larger version Ultraviolet/GALEX Click on image for larger version Poster Version Click on image for larger version The unique ultraviolet vision of NASA's Galaxy Evolution Explorer reveals, for the first time, dwarf galaxies forming out of nothing more than pristine gas likely leftover from the early universe. Dwarf galaxies are relatively small collections of stars that often orbit around larger galaxies like our Milky Way. The forming dwarf galaxies shine in the far ultraviolet spectrum, rendered as blue in the call-out on the right hand side of this image. Near ultraviolet light, also obtained by the Galaxy Evolution Explorer, is displayed in green, and visible light from the blue part of the spectrum here is represented by red. The clumps (in circles) are distinctively blue, indicating they are primarily detected in far ultraviolet light. The faint blue overlay traces the outline of the Leo Ring, a huge cloud of hydrogen and helium that orbits around two massive galaxies in the constellation Leo (left panel). The cloud is thought likely to be a primordial object, an ancient remnant of material that has remained relatively unchanged since the very earliest days of the universe. Identified about 25 years ago by radio waves, the ring cannot be seen in visible light. Only a portion of the Leo Ring has been imaged in the ultraviolet, but this section contains the telltale ultraviolet signature of recent massive star formation within this ring of pristine gas. Astronomers have previously only seen dwarf galaxies form out of gas that has already been cycled through a galaxy and enriched with metals elements heavier than helium produced as stars evolve. The visible data come from the Digitized Sky Survey of the Space Telescope Science Institute in Baltimore, Md. The Leo Ring visible image (left

Ways of seeing evaluation

OpenAIRE

Bryant, W; Wilson, L; Lawson, J

2011-01-01

Copyright @ 2011 Brunel University This report summarises the evaluation of Ways of Seeing, a community arts project funded by the Heritage Lottery Fund and hosted by the Lightbox, Woking, Surrey from 2008-11. The people involved have had remarkable experiences, choosing how to take part in each stage of preparations for a major public art exhibition. All those involved had disabilities, primarily arising from mental health issues but also including physical disabilities. The project was s...

Seeing and Experiencing Relativity--A New Tool for Teaching?

Science.gov (United States)

Kortemeyer, Gerd; Fish, Jordan; Hacker, Jesse; Kienle, Justin; Kobylarek, Alexander; Sigler, Michael; Wierenga, Bert; Cheu, Ryan; Kim, Ebae; Sherin, Zach; Sidhu, Sonny; Tan, Philip

2013-01-01

"What would you see if you were riding a beam of light?" This thought experiment, which Einstein reports to have "conducted" at the age of 16, of course has no sensible answer: as Einstein published a decade later, you could never reach the speed of light. But it does make sense to ask what you would see if you were traveling…

How often should we monitor for reliable detection of atrial fibrillation recurrence? Efficiency considerations and implications for study design.

Directory of Open Access Journals (Sweden)

Efstratios I Charitos

Full Text Available Although atrial fibrillation (AF recurrence is unpredictable in terms of onset and duration, current intermittent rhythm monitoring (IRM diagnostic modalities are short-termed and discontinuous. The aim of the present study was to investigate the necessary IRM frequency required to reliably detect recurrence of various AF recurrence patterns.The rhythm histories of 647 patients (mean AF burden: 12 ± 22% of monitored time; 687 patient-years with implantable continuous monitoring devices were reconstructed and analyzed. With the use of computationally intensive simulation, we evaluated the necessary IRM frequency to reliably detect AF recurrence of various AF phenotypes using IRM of various durations.The IRM frequency required for reliable AF detection depends on the amount and temporal aggregation of the AF recurrence (p95% sensitivity of AF recurrence required higher IRM frequencies (>12 24-hour; >6 7-day; >4 14-day; >3 30-day IRM per year; p<0.0001 than currently recommended. Lower IRM frequencies will under-detect AF recurrence and introduce significant bias in the evaluation of therapeutic interventions. More frequent but of shorter duration, IRMs (24-hour are significantly more time effective (sensitivity per monitored time than a fewer number of longer IRM durations (p<0.0001.Reliable AF recurrence detection requires higher IRM frequencies than currently recommended. Current IRM frequency recommendations will fail to diagnose a significant proportion of patients. Shorter duration but more frequent IRM strategies are significantly more efficient than longer IRM durations.Unique identifier: NCT00806689.

Some normed binomial difference sequence spaces related to the [Formula: see text] spaces.

Science.gov (United States)

Song, Meimei; Meng, Jian

2017-01-01

The aim of this paper is to introduce the normed binomial sequence spaces [Formula: see text] by combining the binomial transformation and difference operator, where [Formula: see text]. We prove that these spaces are linearly isomorphic to the spaces [Formula: see text] and [Formula: see text], respectively. Furthermore, we compute Schauder bases and the α -, β - and γ -duals of these sequence spaces.

Training the DoD Software Acquisition Professional

Science.gov (United States)

2015-02-01

Systems Acquisition (Information Resource Management ( IRM )), IRM101 (Level 1). This is a distance learning course (online course). This course...experience. 3. Advanced Systems Acquisition, IRM304 (Level 3 First Course). This is a classroom graduate-level experience. This course focuses on the IRM ...IT courses. Why IRM and SAM? Years ago, there were separate SAM and IRM courses at each level. However, with the Services request to decrease

Determining astronomical seeing conditions at Matjiesfontein by optical and turbulence methods

Energy Technology Data Exchange (ETDEWEB)

Nickola, M [Hartebeesthoek Radio Astronomy Observatory (HartRAO) Space Geodesy Programme, PO Box 443, Krugersdorp 1740 (South Africa); Esau, I [G.C. Rieber Climate Institute of the Nansen Environmental and Remote Sensing Center (NERSC), Thoermohlensgate 47, N-5006 Bergen (Norway); Djolov, G [University of Pretoria, Department of Geography, Geoinformatics and Meteorology, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria 0002 (South Africa)

2010-08-15

Matjiesfontein in the Karoo has been proposed as a suitable location for a new fundamental space geodetic observatory. On-site geodetic equipment will include a Lunar Laser Ranger (LLR). LLR requires sub-arcsecond optical seeing conditions for delivery of high quality and quantity data. Seeing conditions at the Matjiesfontein site will be evaluated by making use of an automated seeing monitor and by modelling atmospheric turbulence with Large Eddy Simulation Nansen Center Improved Code (LESNIC).

Rationality, perception, and the all-seeing eye.

Science.gov (United States)

Felin, Teppo; Koenderink, Jan; Krueger, Joachim I

2017-08-01

Seeing-perception and vision-is implicitly the fundamental building block of the literature on rationality and cognition. Herbert Simon and Daniel Kahneman's arguments against the omniscience of economic agents-and the concept of bounded rationality-depend critically on a particular view of the nature of perception and vision. We propose that this framework of rationality merely replaces economic omniscience with perceptual omniscience. We show how the cognitive and social sciences feature a pervasive but problematic meta-assumption that is characterized by an "all-seeing eye." We raise concerns about this assumption and discuss different ways in which the all-seeing eye manifests itself in existing research on (bounded) rationality. We first consider the centrality of vision and perception in Simon's pioneering work. We then point to Kahneman's work-particularly his article "Maps of Bounded Rationality"-to illustrate the pervasiveness of an all-seeing view of perception, as manifested in the extensive use of visual examples and illusions. Similar assumptions about perception can be found across a large literature in the cognitive sciences. The central problem is the present emphasis on inverse optics-the objective nature of objects and environments, e.g., size, contrast, and color. This framework ignores the nature of the organism and perceiver. We argue instead that reality is constructed and expressed, and we discuss the species-specificity of perception, as well as perception as a user interface. We draw on vision science as well as the arts to develop an alternative understanding of rationality in the cognitive and social sciences. We conclude with a discussion of the implications of our arguments for the rationality and decision-making literature in cognitive psychology and behavioral economics, along with suggesting some ways forward.

The association between individual counselling and health behaviour change: the See Kidney Disease (SeeKD) targeted screening programme for chronic kidney disease

OpenAIRE

Galbraith, Lauren; Hemmelgarn, Brenda; Manns, Braden; Samuel, Susan; Kappel, Joanne; Valk, Nadine; Ronksley, Paul

2016-01-01

Background Health behaviour change is an important component of management for patients with chronic kidney disease (CKD); however, the optimal method to promote health behaviour change for self-management of CKD is unknown. The See Kidney Disease (SeeKD) targeted screening programme screened Canadians at risk for CKD and promoted health behaviour change through individual counselling and goal setting. Objectives The objectives of this study are to determine the effectiveness of individual co...

Heavy-Ions induced SEE effects measurements for the STRURED ASIC

International Nuclear Information System (INIS)

De Robertis, G.; Ranieri, A.; Gabrielli, A.; Candelori, A.; Mattiazzo, S.; Pantano, D.; Tessaro, M.

2011-01-01

With the aim of developing a radiation-tolerant circuit, a digital test microelectronic device has been designed and fabricated by using a standard-cell library of a 130-nm CMOS technology, including three different architectures to correct circuit malfunctions induced by the occurrence of Single-Event Effects (SEE's). SEE's are one of the main reasons of failures affecting electronic circuits operating in harsh radiation environments, such as in experiments performed at High Energy Physics (HEP) colliders or in apparatus to be operated in Space. On the same digital circuit specifically designed, three redundant architectures added to a basic scheme have been implemented in order to evaluate their effectiveness to prevent SEE. This may give an indication on their usage in future digital circuits specifically designed for the above mentioned applications. We present the results of SEE cross section measurements performed on a test digital device exposed to a high energy heavy ion beam at the SIRAD irradiation facility of the INFN National Laboratories of Legnaro (Padova Italy).

Seeing Objects as Faces Enhances Object Detection.

Science.gov (United States)

Takahashi, Kohske; Watanabe, Katsumi

2015-10-01

The face is a special visual stimulus. Both bottom-up processes for low-level facial features and top-down modulation by face expectations contribute to the advantages of face perception. However, it is hard to dissociate the top-down factors from the bottom-up processes, since facial stimuli mandatorily lead to face awareness. In the present study, using the face pareidolia phenomenon, we demonstrated that face awareness, namely seeing an object as a face, enhances object detection performance. In face pareidolia, some people see a visual stimulus, for example, three dots arranged in V shape, as a face, while others do not. This phenomenon allows us to investigate the effect of face awareness leaving the stimulus per se unchanged. Participants were asked to detect a face target or a triangle target. While target per se was identical between the two tasks, the detection sensitivity was higher when the participants recognized the target as a face. This was the case irrespective of the stimulus eccentricity or the vertical orientation of the stimulus. These results demonstrate that seeing an object as a face facilitates object detection via top-down modulation. The advantages of face perception are, therefore, at least partly, due to face awareness.

Seeing Objects as Faces Enhances Object Detection

Directory of Open Access Journals (Sweden)

Kohske Takahashi

2015-09-01

Full Text Available The face is a special visual stimulus. Both bottom-up processes for low-level facial features and top-down modulation by face expectations contribute to the advantages of face perception. However, it is hard to dissociate the top-down factors from the bottom-up processes, since facial stimuli mandatorily lead to face awareness. In the present study, using the face pareidolia phenomenon, we demonstrated that face awareness, namely seeing an object as a face, enhances object detection performance. In face pareidolia, some people see a visual stimulus, for example, three dots arranged in V shape, as a face, while others do not. This phenomenon allows us to investigate the effect of face awareness leaving the stimulus per se unchanged. Participants were asked to detect a face target or a triangle target. While target per se was identical between the two tasks, the detection sensitivity was higher when the participants recognized the target as a face. This was the case irrespective of the stimulus eccentricity or the vertical orientation of the stimulus. These results demonstrate that seeing an object as a face facilitates object detection via top-down modulation. The advantages of face perception are, therefore, at least partly, due to face awareness.

CERN pursues its partnership with the Department of Haute-Savoie

CERN Multimedia

CERN Bulletin

2010-01-01

The third framework agreement between CERN and the Department of Haute-Savoie was signed at an official ceremony in Archamps, Haute Savoie, on 4 February 2010. The main theme of the agreement, which lays down the guidelines for collaboration between the two parties, is the transfer of knowledge and technology.   Christian Monteil (left), Chairman of the General Council of Haute-Savoie and Rolf Heuer, Director-General of CERN after the third signature of the convention-cadre between Haute-Savoie and CERN. CERN and Haute Savoie have a long tradition of cooperation. Fourteen years after their first agreement (see box), the two parties have just signed a third framework agreement that adds knowledge transfer to the range of items covered. The Department of Haute-Savoie wishes to place the focus on advanced and unique training in areas where CERN has considerable expertise. "Two highly successful schools in which CERN is directly involved, one on accelerator physics and the other on medical ap...

Comparison of gas chromatography/isotope ratio mass spectrometry and liquid chromatography/isotope ratio mass spectrometry for carbon stable-isotope analysis of carbohydrates.

Science.gov (United States)

Moerdijk-Poortvliet, Tanja C W; Schierbeek, Henk; Houtekamer, Marco; van Engeland, Tom; Derrien, Delphine; Stal, Lucas J; Boschker, Henricus T S

2015-07-15

We compared gas chromatography/isotope ratio mass spectrometry (GC/IRMS) and liquid chromatography/isotope ratio mass spectrometry (LC/IRMS) for the measurement of δ(13)C values in carbohydrates. Contrary to GC/IRMS, no derivatisation is needed for LC/IRMS analysis of carbohydrates. Hence, although LC/IRMS is expected to be more accurate and precise, no direct comparison has been reported. GC/IRMS with the aldonitrile penta-acetate (ANPA) derivatisation method was compared with LC/IRMS without derivatisation. A large number of glucose standards and a variety of natural samples were analysed for five neutral carbohydrates at natural abundance as well as at (13)C-enriched levels. Gas chromatography/chemical ionisation mass spectrometry (GC/CIMS) was applied to check for incomplete derivatisation of the carbohydrate, which would impair the accuracy of the GC/IRMS method. The LC/IRMS technique provided excellent precision (±0.08‰ and ±3.1‰ at natural abundance and enrichment levels, respectively) for the glucose standards and this technique proved to be superior to GC/IRMS (±0.62‰ and ±19.8‰ at natural abundance and enrichment levels, respectively). For GC/IRMS measurements the derivatisation correction and the conversion of carbohydrates into CO2 had a considerable effect on the measured δ(13)C values. However, we did not find any significant differences in the accuracy of the two techniques over the full range of natural δ(13)C abundances and (13)C-labelled glucose. The difference in the performance of GC/IRMS and LC/IRMS diminished when the δ(13)C values were measured in natural samples, because the chromatographic performance and background correction became critical factors, particularly for LC/IRMS. The derivatisation of carbohydrates for the GC/IRMS method was complete. Although both LC/IRMS and GC/IRMS are reliable techniques for compound-specific stable carbon isotope analysis of carbohydrates (provided that derivatisation is complete and the

Validation of GC-IRMS techniques for δ13C and δ2H CSIA of organophosphorus compounds and their potential for studying the mode of hydrolysis in the environment.

Science.gov (United States)

Wu, Langping; Kümmel, Steffen; Richnow, Hans H

2017-04-01

Compound-specific stable isotope analysis (CSIA) is among the most promising tools for studying the fate of organic pollutants in the environment. However, the feasibility of multidimensional CSIA was limited by the availability of a robust method for precise isotope analysis of heteroatom-bearing organic compounds. We developed a method for δ 13 C and δ 2 H analysis of eight organophosphorus compounds (OPs) with different chemical properties. In particular, we aimed to compare high-temperature conversion (HTC) and chromium-based HTC (Cr/HTC) units to explore the limitations of hydrogen isotope analysis of heteroatom-bearing compounds. Analysis of the amount dependency of the isotope values (linearity analysis) of OPs indicated that the formation of HCl was a significant isotope fractionation process leading to inaccurate δ 2 H analysis in HTC. In the case of nonchlorinated OPs, by-product formation of HCN, H 2 S, or PH 3 in HTC was observed but did not affect the dynamic range of reproducible isotope values above the limit of detection. No hydrogen-containing by-products were found in the Cr/HTC process by use of ion trap mass spectrometry analysis. The accuracy of gas chromatography - isotope ratio mass spectrometry was validated in comparison with elemental analyzer - isotope ratio mass spectrometry. Dual-isotope fractionation yielded Λ values of 0 ± 0 at pH 7, 7 ± 1 at pH 9, and 30 ± 6 at pH 12, indicating the potential of 2D CSIA to characterize the hydrolysis mechanisms of OPs. This is the first report on the combination of δ 2 H and δ 13 C isotope analysis of OPs, and this is the first study providing a systematic evaluation of HTC and Cr/HTC for hydrogen isotope analysis using OPs as target compounds. Graphical Abstract Comparison of δ 2 H measurement of non-chlorinated and chlorinated OPs via GC-Cr/HTC-IRMS and GC-HTC-IRMS system.

76 FR 26333 - U.S. Department of State Advisory Committee on Private International Law (ACPIL); Notice of...

Science.gov (United States)

2011-05-06

... Choice of Court Agreements. The meeting will take place on June 15, 2011 from 9 a.m. to 2 p.m. EDT at the... and Place: The meeting will take place on June 15th from 9 a.m. to 2 p.m. EDT at the Office of the... validate the identity of individuals who enter Department facilities. Please see the Privacy Impact...

On-line measurement of 13C/12C and 15N/14N ratios by E/A-diluter-IRMS

International Nuclear Information System (INIS)

Foerstel, H.; Boner, M.; Prast, H.

2001-01-01

Efficient food control requires rapid procedures for testing source authenticity. Food is produced inside a closed 'isotopic environment' from where it inherits a specific isotopic composition or fingerprint. Isotope ratio mass spectrometry (IRMS) measures isotopic compositions using simple gases like CO 2 or N 2 exclusively. From food samples these gases may be produced by combustion in a commercial CHN analyser (Elemental Analyser, EA). Following GC separation of the combustion gases the elemental content is determined using a thermal conductivity detector (TCD) . The effluent of the EA is coupled to the mass spectrometer via an open split. Because the relative amounts of the bio-elements vary significantly, (often C/N is 25/1 or larger), the amount of analyte gas produced from a single sample must be adjusted e.g. using a diluter. Our diluter configuration can be adjusted to measure repeatedly the 13 C/ 12 C ratio of carbon dioxide in mineral waters, as well as to measure 15 N/ 14 N and 13 C/ 12 C ratios from biological or soil samples simultaneously. In the first application different types of carbon dioxide, produced naturally (well) or technically (process), can be distinguished. The second application offers the possibility to trace the fate of a fertilizer in vineyards by determining the isotopic variation of nitrogen and carbon in soil and vines. (author)

Analytical Method for Carbon and Oxygen Isotope of Small Carbonate Samples with the GasBench Ⅱ-IRMS Device

Directory of Open Access Journals (Sweden)

LIANG Cui-cui

2015-01-01

Full Text Available An analytical method for measuring carbon and oxygen isotopic compositions of trace amount carbonate (＞15 μg was established by Delta V Advantage isotope Ratio MS coupled with GasBench Ⅱ. Different trace amount (5-50 μg carbonate standard samples (IAEA-CO-1 were measured by GasBench Ⅱ with 12 mL and 3.7 mL vials. When the weight of samples was less than 40 μg and it was acidified in 12 mL vials, most standard deviations of the δ13C and δ18O were more than 0.1‰, which couldn’t satisfied high-precision measurements. When the weight of samples was greater than 15 μg and it was acidified in 3.7 mL vials, standard deviations for the δ13C and δ18O were 0.01‰-0.07‰ and 0.01‰-0.08‰ respectively, which satisfied high-precision measurements. Therefore, small 3.7 mL vials were used to increase the concentration of carbon dioxide in headspace, carbonate samples even less as 15 μg can be analyzed routinely by a GasBench Ⅱ continuous-flow IRMS. Meanwhile, the linear relationship between sample’s weight and peak’s area was strong (R2＞0.993 2 and it can be used to determine the carbon content of carbonate samples.

Seeing deconvolution of globular clusters in M31

International Nuclear Information System (INIS)

Bendinelli, O.; Zavatti, F.; Parmeggiani, G.; Djorgovski, S.

1990-01-01

The morphology of six M31 globular clusters is examined using seeing-deconvolved CCD images. The deconvolution techniques developed by Bendinelli (1989) are reviewed and applied to the M31 globular clusters to demonstrate the methodology. It is found that the effective resolution limit of the method is about 0.1-0.3 arcsec for CCD images obtained in FWHM = 1 arcsec seeing, and sampling of 0.3 arcsec/pixel. Also, the robustness of the method is discussed. The implications of the technique for future studies using data from the Hubble Space Telescope are considered. 68 refs

Heavy-Ions induced SEE effects measurements for the STRURED ASIC

Energy Technology Data Exchange (ETDEWEB)

De Robertis, G.; Ranieri, A. [INFN Bari, Via Orabona 4, 70126 Bari (Italy); Gabrielli, A. [Universita degli Studi di Bologna and INFN-Bologna, Viale B. Pichat, 6/2, 40127 Bologna (Italy); Candelori, A.; Mattiazzo, S.; Pantano, D.; Tessaro, M. [INFN-Padova, Via Marzolo 8, 35131 Padova (Italy)

2011-06-15

With the aim of developing a radiation-tolerant circuit, a digital test microelectronic device has been designed and fabricated by using a standard-cell library of a 130-nm CMOS technology, including three different architectures to correct circuit malfunctions induced by the occurrence of Single-Event Effects (SEE's). SEE's are one of the main reasons of failures affecting electronic circuits operating in harsh radiation environments, such as in experiments performed at High Energy Physics (HEP) colliders or in apparatus to be operated in Space. On the same digital circuit specifically designed, three redundant architectures added to a basic scheme have been implemented in order to evaluate their effectiveness to prevent SEE. This may give an indication on their usage in future digital circuits specifically designed for the above mentioned applications. We present the results of SEE cross section measurements performed on a test digital device exposed to a high energy heavy ion beam at the SIRAD irradiation facility of the INFN National Laboratories of Legnaro (Padova Italy).

Department of Training and Consulting: Overview

International Nuclear Information System (INIS)

Dobrzynski, L.

2002-01-01

The main activity of the Department is centered on the education of pupils, students and social groups interested in ionizing radiation. The number of visitors to our Department is steadily growing. Whereas in the year 2000 we were visited by about 2100 students from various secondary schools, this number more than doubled in 2001, when it passed 5200. One day was dedicated to a meeting with a group of science teachers-methodologists. A collaboration with the National Center for Supporting Vocational Education, Warsaw, has started and will hopefully bring interesting results. In addition, the Department organized professional courses on radiation protection for employees (accelerator operators and management personnel) of the Institute. An important innovation in our activity is the opening of the Laboratory of Atomic and Nuclear Physics dedicated mainly to high-schools. However, the equipment gathered in the laboratory permits one to conduct experiments on the level of the university students lab. First groups of both, secondary school pupils as well as students of physics, have already worked in our laboratory. The Department also arranged one month training for pupils from one of the technical schools of environmental protection in Konstancin near Warsaw. In addition to the experimental setups already in the Laboratory, a solid-state AMPTEK detector was put into operation in conjunction with X-ray scattering facility. Because of this innovation, one can now study not only the production of X-rays, their wave properties and transmission through various materials, but also observe Compton scattering, thus seeing the dual nature of X-rays. Because a new set-up which shows diffraction of electrons was also put into operation, one can additionally learn about the wave-particle duality for the case of massive particles. Scientific activity was quite varied which is illustrated by the titles of papers published. However, one should stress that the main experiments were

29 CFR 1918.55 - Cranes (See also § 1918.11).

Science.gov (United States)

2010-07-01

... 29 Labor 7 2010-07-01 2010-07-01 false Cranes (See also § 1918.11). 1918.55 Section 1918.55 Labor... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Vessel's Cargo Handling Gear § 1918.55 Cranes (See also § 1918.11). The following requirements shall apply to the use of cranes forming part of a vessel's...

Statistical model for classifying the feeding systems of Iberian pigs through Gas Chromatography (GC-FID and Isotope Ratio Mass Spectrometry (GC-C-IRMS

Directory of Open Access Journals (Sweden)

García-Casco, J. M.

2013-04-01

Full Text Available In the present work we have analyzed a total of 734 subcutaneous fat samples from Iberian pigs with different feeding systems for fattening (“Bellota”, “Recebo”, “Campo” and “Cebo” over three consecutive years, 2009-2011. Lipids were extracted from the subcutaneous fat on the rump, and after esterification, they were analyzed by Gas Chromatography (GC-FID and Gas Chromatography- Combustion-Isotope Ratio Mass Spectrometry (GC-C-IRMS. Mean fatty acids and isotope ratios show that there are differences according to the year and feeding systems, two factors that should be taken into account when classifying the animals. The application of different prediction models based on Discriminant analysis has allowed us to establish a method for the classification of animals according to the feeding system type, with a correct percentage of 85% using three or four classification categories (Bellota, Recebo, Campo and/or Cebo and 91% using only two categories, Cebo and Bellota. This model could provide the basis for appropriate classification of Iberian pigs according to their feeding regime.En el presente trabajo se han analizado un total de 734 muestras de tejido subcutáneo de cerdos ibéricos con distintos tipos de alimentación de engorde (Bellota, Recebo, Cebo y Campo a lo largo de tres años consecutivos, 2009-2011. Se han extraído los lípidos de la grasa subcutánea de rabadilla, y después de su esterificación, se han analizado por Cromatografía de gases (GC-FID y por Espectrometría de masas de relaciones isotópicas (GC-C-IRMS. Las medias de los ácidos grasos y de las relaciones isotópicas muestran que existen diferencias según el año y tipo de alimentación, factores que deberían tenerse en cuenta a la hora de clasificar los animales. La aplicación de distintos modelos de predicción basados en análisis discriminante permite establecer un método para la clasificación de los animales según el tipo de alimentación, con

Estimating the mirror seeing for a large optical telescope with a numerical method

Science.gov (United States)

Zhang, En-Peng; Cui, Xiang-Qun; Li, Guo-Ping; Zhang, Yong; Shi, Jian-Rong; Zhao, Yong-Heng

2018-05-01

It is widely accepted that mirror seeing is caused by turbulent fluctuations in the index of air refraction in the vicinity of a telescope mirror. Computational Fluid Dynamics (CFD) is a useful tool to evaluate the effects of mirror seeing. In this paper, we present a numerical method to estimate the mirror seeing for a large optical telescope (∼ 4 m) in cases of natural convection with the ANSYS ICEPAK software. We get the FWHM of the image for different inclination angles (i) of the mirror and different temperature differences (ΔT) between the mirror and ambient air. Our results show that the mirror seeing depends very weakly on i, which agrees with observational data from the Canada-France-Hawaii Telescope. The numerical model can be used to estimate mirror seeing in the case of natural convection although with some limitations. We can determine ΔT for thermal control of the primary mirror according to the simulation, empirical data and site seeing.

See one, do one, teach one: advanced technology in medical education.

Science.gov (United States)

Vozenilek, John; Huff, J Stephen; Reznek, Martin; Gordon, James A

2004-11-01

The concept of "learning by doing" has become less acceptable, particularly when invasive procedures and high-risk care are required. Restrictions on medical educators have prompted them to seek alternative methods to teach medical knowledge and gain procedural experience. Fortunately, the last decade has seen an explosion of the number of tools available to enhance medical education: web-based education, virtual reality, and high fidelity patient simulation. This paper presents some of the consensus statements in regard to these tools agreed upon by members of the Educational Technology Section of the 2004 AEM Consensus Conference for Informatics and Technology in Emergency Department Health Care, held in Orlando, Florida. Web-based teaching: 1) Every ED should have access to medical educational materials via the Internet, computer-based training, and other effective education methods for point-of-service information, continuing medical education, and training. 2) Real-time automated tools should be integrated into Emergency Department Information Systems [EDIS] for contemporaneous education. Virtual reality [VR]: 1) Emergency physicians and emergency medicine societies should become more involved in VR development and assessment. 2) Nationally accepted protocols for the proper assessment of VR applications should be adopted and large multi-center groups should be formed to perform these studies. High-fidelity simulation: Emergency medicine residency programs should consider the use of high-fidelity patient simulators to enhance the teaching and evaluation of core competencies among trainees. Across specialties, patient simulation, virtual reality, and the Web will soon enable medical students and residents to... see one, simulate many, do one competently, and teach everyone.

See-saw enhancement of neutrino mixing due to the right-handed phases

International Nuclear Information System (INIS)

Tanimoto, M.

1994-11-01

We study the see-saw enhancement mechanism in presence of the right-handed phases of the Dirac neutrino mass matrix and the Majorana mass matrix. The enhancement condition given by Smirnov is modified. We point out that the see-saw enhancement could be obtained due to the right-handed phases even if the Majorana matrix is proportional to the unit matrix. We show a realistic Dirac mass matrix which causes the see-saw enhancement. (author)

Leptogenesis in unified theories with Type II see-saw

International Nuclear Information System (INIS)

Antusch, Stefan; King, Steve F.

2006-01-01

In some classes of flavour models based on unified theories with a type I see-saw mechanism, the prediction for the mass of the lightest right-handed neutrino is in conflict with the lower bound from the requirement of successful thermal leptogenesis. We investigate how lifting the absolute neutrino mass scale by adding a type II see-saw contribution proportional to the unit matrix can solve this problem. Generically, lifting the neutrino mass scale increases the prediction for the mass of the lightest right-handed neutrino while the decay asymmetry is enhanced and washout effects are reduced, relaxing the lower bound on the mass of the lightest right-handed neutrino from thermal leptogenesis. For instance in classes of unified theories where the lightest right-handed neutrino dominates the type I see-saw contribution, we find that thermal leptogenesis becomes possible if the neutrino mass scale is larger than about 0.15 eV, making this scenario testable by neutrinoless double beta decay experiments in the near future

Agricultura familiar e as rendas não-agrícolas na Região Metropolitana de Porto Alegre : um estudo de caso dos municípios de Dois Irmãos e Ivoti - RS

OpenAIRE

Marco Antonio Verardi Fialho

2000-01-01

Esta estudo discute a importância das rendas não-agrícolas na composição da renda total dos agricultores familiares de uma região fortemente marcada pela pluriatividade de seus produtores rurais. Os dados utilizados neste estudo foram obtidos a partir de uma pesquisa de campo realizada junto a 57 agricultores familiares dos municípios de Dois Irmãos e Ivoti, RS. A metodologia utilizada consistiu na identificação e quantificação das rendas agrícolas e não-agrícolas bem como na caracterização d...

IRMES 2006 – ISTRAŽIVANJE I RAZVOJ MAŠINSKIH ELEMENATA I SISTEMA – prikaz naučno-stručnog skupa

Directory of Open Access Journals (Sweden)

Vlado P. Đurković

2007-04-01

Full Text Available U organizaciji asocijacije za dizajn, elemente i konstrukcije, pod nazivom ADEKO 21. i 22. septembra na Mrakovici u Republici Srpskoj održano je međunarodno savetovanje IRMES 2006. Izvršni organizator bio je Mašinski fakultet iz Banje Luke, a pokrovitelj Ministarstvo nauke i tehnologije Republike Srpske. Pre održavanja samog skupa, kako je to već ustaljena praksa, štampan je zbornik radova na 428 stranica, čiji je redaktor dr Milosav Đurđević, docent na Mašinskom fakultetu Banja Luka, a predsednik Programskog odbora bio je dr Vojislav Miltenović, profesor na Mašinskom fakultetu u Nišu. U predgovoru zbornika konstatovano je da je u poslednjoj deceniji XX veka razvoj proizvodnog mašinstva bio usporen, a ponegde čak i zaustavljen. Ovakav tok razvoja posebno je prisutan u mašinogradnji i metalskoj industriji koje bitno utiču na intenzitet razvoja drugih privrednih grana, kao i obrazovanje stručnjaka svih profila u području proizvodnih tehnika i tehnologija. I pored takve situacije, u ovim privrednim granama ipak se obrazovanju kadrova i naučnoistraživačkom radu posvećuje dužna pažnja.

Seeing the animal

DEFF Research Database (Denmark)

Harfeld, Jes Lynning; Cornou, Cecile; Kornum, Anna

2016-01-01

This article discusses the notion that the invisibility of the animalness of the animal constitutes a fundamental obstacle to change within current production systems. It is discussed whether housing animals in environments that resemble natural habitats could lead to a re-animalization...... of the animals, a higher appreciation of their moral significance, and thereby higher standards of animal welfare. The basic claim is that experiencing the animals in their evolutionary and environmental context would make it harder to objectify animals as mere bioreactors and production systems. It is argued...... that the historic objectification of animals within intensive animal production can only be reversed if animals are given the chance to express themselves as they are and not as we see them through the tunnel visions of economy and quantifiable welfare assessment parameters....

Seleção de progênies de meio-irmãos de milho para eficiência no uso de nitrogênio Selection of half-sib of maize for nitrogen use efficiency

Directory of Open Access Journals (Sweden)

Rafael Heinz

2012-12-01

Full Text Available O trabalho teve por objetivo estimar os parâmetros e os ganhos genéticos na seleção de progênies de meio-irmãos para eficiência no uso de nitrogênio, por meio de seleção simultânea de caracteres. Foram instalados dois experimentos, diferenciados pela adubação nitrogenada, sendo um com adubação adequada (alto N e outro em condição de estresse (baixo N. O delineamento experimental utilizado foi em látice 10x10, com duas repetições. Nos ensaios foram utilizadas 84 progênies de meio-irmãos e 16 testemunhas. A partir dos quadrados médios das análises de variâncias de cada ambiente foram realizadas as estimativas dos parâmetros genéticos. Após as análises, foram selecionadas em cada ambiente 17 progênies de meio-irmãos, por meio do índice clássico de seleção, e verificou-se a repetibilidade das progênies entre os ambientes. Observou-se variabilidade entre as progênies, determinando o potencial da população para a seleção considerando-se a eficiência no uso de nitrogênio. As estimativas de parâmetros e ganhos genéticos foram maiores em alto N. O uso do índice de seleção promoveu estimativas de ganho por seleção de 24,43 e 21,05% para alto e baixo N, respectivamente, para a produtividade de grãos. As progênies selecionadas apresentaram médias de produtividade de grãos de 13,45 e 19,47% maiores que as testemunhas, em alto e baixo N, respectivamente.The study aimed to estimate the parameters and the genetic gain in selection of half-sib for nitrogen use efficiency, through simultaneous selection of characters. Two experiments were established, differentiated by nitrogen fertilization, one with proper fertilization (high N and another in stress conditions (low N. The experiment was using a 10x10 lattice with two replications. In the tests we used 84 different half-sib and 16 witnesses. From the mean squares of analysis of variance in each environment were the estimates of genetic parameters. After the

``To See Cosmology in a Quetzal..."

Science.gov (United States)

Neuenschwander, D. E.; Finkenbinder, L.

2002-05-01

High in the Talamanca Mountains of Costa Rica, our university maintains a field station called the Quetzal Education Research Center (QERC), in cloud forest habit of the magnificent Resplendent Quetzal. At these latitudes, where every surface is alive, the astronomical realities that constrain life's options acquire an in-your-face immediacy. Three years ago we began team-teaching a general astrobiology course featuring a 10-day trip to the QERC and other Costa Rican sites, including the Arenal Volcano and Manuel Antonio National Park. This experience places the student smack in the middle of an environment that dramatically shows how stellar evolution provides the energy, materials, and timescale for biological evolution. For example, discussion of tidal forces occurs when we are up to our necks in the tide at Manuel Antonio's beaches; discussions of nuclear reactions that power the Sun are followed with extended forest hikes to see the light-gathering strategies of photosynthetic organisms; as an astronomical system, quetzal DNA is a ``metal," a product of nucleosynthesis. Our time in Costa Rica also features an astronomy education program for the residents of San Gerardo de Dota (in the rural valley where the QERC is located), with presentations at the local school and astronomy ``open house" evenings at the QERC. As one travels the country one also sees the rapid destruction of tropical forest biodiversity. We therefore encourage through astrobiology the formation of another kind of ``ecosystem:" the global network of young people who are valiantly confronting the challenges of environmental sustainability. Solutions to these problems must take into account economic, cultural, and political realities as well as scientific realities. The importance of seeing these immediate problems in terms of astronomical and biological evolution timescales forms another splendid motivation for the study of astrobiology.

Liquid and gas chromatography coupled to isotope ratio mass spectrometry for the determination of 13C-valine isotopic ratios in complex biological samples.

Science.gov (United States)

Godin, Jean-Philippe; Breuillé, Denis; Obled, Christiane; Papet, Isabelle; Schierbeek, Henk; Hopfgartner, Gérard; Fay, Laurent-Bernard

2008-10-01

On-line gas chromatography-combustion-isotope ratio mass spectrometry (GC-C-IRMS) is commonly used to measure isotopic ratios at natural abundance as well as for tracer studies in nutritional and medical research. However, high-precision (13)C isotopic enrichment can also be measured by liquid chromatography-isotope ratio mass spectrometry (LC-IRMS). Indeed, LC-IRMS can be used, as shown by the new method reported here, to obtain a baseline separation and to measure (13)C isotopic enrichment of underivatised amino acids (Asp, Thr-Ser, Glu, Pro, Gly, Ala, Cys and Val). In case of Val, at natural abundance, the SD(delta(13)C) reported with this method was found to be below 1 per thousand . Another key feature of the new LC-IRMS method reported in this paper is the comparison of the LC-IRMS approach with the conventional GC-C-IRMS determination. To perform this comparative study, isotopic enrichments were measured from underivatised Val and its N(O, S)-ethoxycarbonyl ethyl ester derivative. Between 0.0 and 1.0 molar percent excess (MPE) (delta(13)C= -12.3 to 150.8 per thousand), the calculated root-mean-square (rms) of SD was 0.38 and 0.46 per thousand and the calculated rms of accuracy was 0.023 and 0.005 MPE, respectively, for GC-C-IRMS and LC-IRMS. Both systems measured accurately low isotopic enrichments (0.002 atom percent excess (APE)) with an SD (APE) of 0.0004. To correlate the relative (delta(13)C) and absolute (atom%, APE and MPE) isotopic enrichment of Val measured by the GC-C-IRMS and LC-IRMS devices, mathematical equations showing the slope and intercept of the curves were established and validated with experimental data between 0.0 to 2.3 MPE. Finally, both GC-C-IRMS and LC-IRMS instruments were also used to assess isotopic enrichment of protein-bound (13)C-Val in tibial epiphysis in a tracer study performed in rats. Isotopic enrichments measured by LC-IRMS and GC-C-IRMS were not statistically different (p>0.05). The results of this work indicate that

Análisis estadístico de Seeing y condiciones ambientales en CASLEO

Science.gov (United States)

Díaz, R. J.; Agüero, M. P.; Levato, H.

We present and discuss the preliminary results from the compilation and homogenization of all the recent seeing observations in CASLEO, together with the environment conditions in the days of the observations. We present also the first determinations of seeing inside the dome of the Helen Sawyer Hogg telescope on the Burek mountain. The seeing at the Burek site has a daily average of FWHM=0.90'' in the sampling period (february-march 2003). This value is an upper limit and is significatively lower than the daily average at the site of the 2.15 m telescope (FWHM=1.39'', 2001-2002). There is no marked correlation between the climatic variables and the seeing, although we mention some trends found in the data. It is possible that a more systematic sampling of the seeing could allow to detect more tight relationships.

Comparison of gas chromatography/isotope ratio mass spectrometry and liquid chromatography/isotope ratio mass spectrometry for carbon stable-isotope analysis of carbohydrates

NARCIS (Netherlands)

Moerdijk-Poortvliet, Tanja C. W.; Schierbeek, Henk; Houtekamer, Marco; van Engeland, Tom; Derrien, Delphine; Stal, Lucas J.; Boschker, Henricus T. S.

2015-01-01

We compared gas chromatography/isotope ratio mass spectrometry (GC/IRMS) and liquid chromatography/isotope ratio mass spectrometry (LC/IRMS) for the measurement of δ(13)C values in carbohydrates. Contrary to GC/IRMS, no derivatisation is needed for LC/IRMS analysis of carbohydrates. Hence, although

Comparison of gas chromatography/isotope ratio mass spectrometry and liquid chromatography/isotope ratio mass spectrometry for carbon stable-isotope analysis of carbohydrates

NARCIS (Netherlands)

Moerdijk-Poortvliet, T.C.W.; Schierbeek, H.; Houtekamer, M.; van Engeland, T.; Derrien, D.; Stal, L.J.; Boschker, H.T.S.

2015-01-01

We compared gas chromatography/isotope ratio mass spectrometry (GC/IRMS) and liquid chromatography/isotope ratio mass spectrometry (LC/IRMS) for the measurement of d13C values in carbohydrates. Contrary to GC/IRMS, no derivatisation is needed for LC/IRMS analysis of carbohydrates. Hence, although

Comparison of gas chromatography/isotope ratio mass spectrometry and liquid chromatography/isotope ratio mass spectrometry for carbon stable-isotope analysis of carbohydrates

NARCIS (Netherlands)

Moerdijk-Poortvliet, T.C.W.; Schierbeek, H.; Houtekamer, M.; van Engeland, T.; Derrien, D.; Stal, L.J.; Boschker, H.T.S.

2015-01-01

Rationale: We compared gas chromatography/isotope ratio mass spectrometry (GC/IRMS) and liquid chromatography/isotope ratio mass spectrometry (LC/IRMS) for the measurement of δ13C values in carbohydrates. Contrary to GC/IRMS, no derivatisation is needed for LC/IRMS analysis of carbohydrates. Hence,

Grid-enabled SEE++, A Grid-Based Medical Decision Support System for Eye Muscle Surgery Conference

CERN Document Server

Schreiner, W.; Buchberger, M.; Kaltofen, T.

2006-01-01

JKU/RISC currently develops in cooperation with Upper Austrian Research (UAR) the SEE-GRID software system. SEE-GRID is based on the SEE++ software for the biomechanical 3D simulation of the human eye and its muscles. SEE++ simulates the common eye muscle surgery techniques in a graphic interactive way that is familiar to an experienced surgeon. SEE++ is world-wide the most advanced software for this purpose; it is used by various hospitals and medical doctors for surgery training and planning, SEE++ deals with the support of diagnosis and treatment of strabismus, which is the common name given to usually persistent or regularly occuring misalignment of the eyes. Strabismus is a visual defect in which eyes point in different directions. A person suffering from it may see double images due to misaligned eyes. SEE++ is able to simulate the result of the Hess-Lancaster test, from which the pathological reason of strabismus can be estimated. The outcome of such an examination is two gaze patterns of blue points a...

Rationality, perception, and the all-seeing eye

NARCIS (Netherlands)

Felin, Teppo; Koenderink, Jan|info:eu-repo/dai/nl/070864543; Krueger, Joachim I

Seeing-perception and vision-is implicitly the fundamental building block of the literature on rationality and cognition. Herbert Simon and Daniel Kahneman's arguments against the omniscience of economic agents-and the concept of bounded rationality-depend critically on a particular view of the

Simpson's neutrino and the singular see-saw

International Nuclear Information System (INIS)

Allen, T.J.; Johnson, R.; Ranfone, S.; Schechter, J.; Walle, J.W.F.

1991-01-01

The authors of this paper derive explicit forms for the neutrino and lepton mixing-matrices which describe the generic singular see-saw model. The dependence on the hierarchy parameter is contrasted with the non-singular case. Application is made to Simpson's 17 keV neutrino

Desempenho psicolinguístico e escolar de irmãos com mielomeningocele Psycholinguistic and school performance of brothers with myelomeningocele

Directory of Open Access Journals (Sweden)

Dionísia Aparecida Cusin Lamônica

2012-08-01

Full Text Available TEMA: mielomeningocele e consequências para o desenvolvimento de habilidades psicolinguísticas e escolares. PROCEDIMENTOS: o objetivo deste estudo foi descrever e refletir sobre o desempenho psicolinguístico e escolar de irmãos com mielomeningocele lombar baixa. Participaram do estudo um menino de 14 anos e 5 meses (P1 e sua irmã de 6 anos e 6 meses (P2. Os procedimentos constaram de entrevista com familiares, Observação do Comportamento Comunicativo (OCC, Teste de Vocabulário por Imagens Peabody - TVIP, Teste Illinóis de Habilidades Psicolinguísticas (ITPA, Perfil de Habilidades Fonológicas (PHF, Teste de Desempenho Escolar (TDE, e Reconhecimento de letras e números (RLN. A análise dos resultados foi descritiva respeitando os manuais dos instrumentos. RESULTADOS: a linguagem oral encontra-se sem alteração evidente. No ITPA e PHF, verificou-se que P1 e P2 apresentaram dificuldade nas habilidades de memória, closura auditiva, expressão verbal, combinação de sons e consciência fonológica. P1 ainda apresentou dificuldade na habilidade de recepção visual e P2 nas habilidades de associação auditiva e closura gramatical. Ambas as crianças apresentaram alteração nas atividades de aprendizagem. CONCLUSÃO: os participantes do estudo apresentaram comportamento comunicativo, habilidades de linguagem oral e vocabulário receptivo sem alterações evidentes. P1 e P2 apresentaram alterações nas habilidades psicolinguísticas bem como no desempenho de atividades envolvendo leitura, escrita e aritmética. As dificuldades apresentadas causam impacto importante nas atividades acadêmicas, demonstrando vulnerabilidade cerebral no sistema de suporte para atividade de aprendizagem.BACKGROUND: meningomyelocele and consequences on the development of psycholinguistic and school abilities. PROCEDURES: the purpose of this study was to describe and reflect on the psycholinguistic and school performance of siblings with low lumbar

Terapia fonológica em irmãos com diferentes graus de gravidade do desvio fonológico Phonological therapy in siblings with different severity degree of phonological disorders

Directory of Open Access Journals (Sweden)

Karina Carlesso Pagliarin

2009-03-01

Full Text Available TEMA: terapia fonológica em irmãos com desvio fonológico. PROCEDIMENTOS: participaram da pesquisa dois irmãos, S1 e S2, do sexo masculino e feminino, respectivamente. O S1, 6:6 de idade, apresentava desvio fonológico de grau severo e foi tratado pelo modelo de Oposições Mínimas e o S2, 4:8 de idade, com desvio fonológico de grau moderado-severo foi tratado pelo Modelo de Oposições Máximas. Ambos os sujeitos realizaram 25 sessões de fonoterapia. RESULTADOS: o S2 obteve uma melhor evolução terapêutica comparado ao S1. O S1 apresentou generalização a itens não utilizados no tratamento e o S2 apresentou generalização dentro de uma classe de sons. CONCLUSÃO: os modelos utilizados são eficazes, pois proporcionaram a ocorrência de generalizações e a melhora do sistema fonológico de ambos os sujeitos. No entanto os fatores ambientais podem ter limitado a evolução do tratamento, uma vez que as crianças apresentavam substituições semelhantes na fala o que favorecia a manutenção da alteração.BACKGROUND: phonological therapy in siblings with phonological disorder. PROCEDURE: the sample was composed of two brothers, S1 and S2, male and female, respectively. S1, age 6:6-year-old, with severe phonological disorder, was treated by Minimal Opposition model and S2, age 4:8-year-old, with moderate-severe phonological disorder, was treated by Maximal Opposition model. Both subjects have had 25 sessions of speech therapy. RESULTS: S2 got better development compared to S1. S1 showed generalization to untreated items and S2 showed generalization within a sound class. CONCLUSION: the used models are effective, because they provided the occurrence of generalizations and the improvement of the phonological system of both subjects. However, environmental factors may have limited the progress of treatment, since that the children had similar substitutions in the speech that favored the maintenance of the change.

δ18O analysis of individual carbohydrates - a new method for GC-pyrolysis-IRMS

Science.gov (United States)

Lehmann, Marco M.; Fischer, Maria; Zech, Michael; Siegwolf, Rolf T. W.; Saurer, Matthias

2015-04-01

Measuring the oxygen isotopic composition (δ18O) of various plant tissues is a widely used tool to investigate biochemical and physiological processes. While we have a good understanding about the hydrological cycle in plants with an evaporative enrichment in 18O in leaf water, we still lack knowledge about the biochemical link between the oxygen atoms in leaf water, leaf assimilates, and stem cellulose and associated isotope fractionations. Especially, the influence of different environmental factors on δ18O of individual carbohydrates (i.e. sugars) and thus on δ18O of cellulose is not fully resolved. A better understanding of these processes may improve climatic reconstructions of tree-ring studies about past environmental conditions. However, further progress in this topic is limited since a precise and reliable method to determine δ18O of individual sugars has not been available yet. With our new approach we attempt to overcome this issue by establishing a new methylation derivatization method suitable for GC-pyrolysis -IRMS. A methyl group (CH3) was thereby added to all hydroxyl groups of a sugar (e.g., glucose, fructose, and sucrose) during a catalyzed one-pot reaction overnight in acetonitrile with methyl iodide (CH3-I) and silver oxide, making them amenable for GC analysis. First results show a very good precision for δ18O of sucrose, but also δ18O of other high-abundant sugars such as glucose and fructose could be measured for the first time. We successfully analyzed a standard mix of all three sugars and determined various other carbohydrates not only related to plant sciences (e.g. mannitol, lactose), showing promising δ18O results. First tests with real plant samples were performed to make this method available for determining δ18O of individual carbohydrates of diverse plant tissues. In future, this new methylation derivatization method should allow us analyzing plant samples of different field sites and of lab experiments to investigate the

Seeing things the philosophy of reliable observation

CERN Document Server

Hudson, Robert

2014-01-01

In Seeing Things, Robert Hudson assesses a common way of arguing about observation reports called "robustness reasoning." Robustness reasoning claims that an observation report is more likely to be true if the report is produced by multiple, independent sources. Seeing Things argues that robustness reasoning lacks the special value it is often claimed to have. Hudson exposes key flaws in various popular philosophical defenses of robustness reasoning. This philosophical critique of robustness is extended by recounting five episodes in the history of science (from experimental microbiology, atomic theory, astrophysics and astronomy) where robustness reasoning is -- or could be claimed to have been -- used. Hudson goes on to show that none of these episodes do in fact exhibit robustness reasoning. In this way, the significance of robustness reasoning is rebutted on both philosophical and historical grounds. But the book does more than critique robustness reasoning. It also develops a better defense of the infor...

Spectrally and Energy Efficient OFDM (SEE-OFDM) for Intensity Modulated Optical Wireless Systems

OpenAIRE

Lam, Emily; Wilson, Sarah Kate; Elgala, Hany; Little, Thomas D. C.

2015-01-01

Spectrally and energy efficient orthogonal frequency division multiplexing (SEE-OFDM) is an optical OFDM technique based on combining multiple asymmetrically clipped optical OFDM (ACO-OFDM) signals into one OFDM signal. By summing different components together, SEE-OFDM can achieve the same spectral efficiency as DC-biased optical OFDM (DCO-OFDM) without an energy-inefficient DC-bias. This paper introduces multiple methods for decoding a SEE-OFDM symbol and shows that an iterative decoder wit...

Single Event Effects (SEE) Testing: Practical Approach to Test Plans

Science.gov (United States)

LaBel, Kenneth A.; Pellish, Jonathan Allen; Berg, Melanie D.

2014-01-01

While standards and guidelines for performing SEE testing have existed for several decades, guidance for developing SEE test plans has not been as easy to find. In this presentation, the variety of areas that need to be considered ranging from resource issues (funds, personnel, schedule) to extremely technical challenges (particle interaction and circuit application), shall be discussed. Note: we consider the approach outlined here as a "living" document: Mission-specific constraints and new technology related issues always need to be taken into account.

New algorithms for identifying the flavour of [Formula: see text] mesons using pions and protons.

Science.gov (United States)

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2017-01-01

Two new algorithms for use in the analysis of [Formula: see text] collision are developed to identify the flavour of [Formula: see text] mesons at production using pions and protons from the hadronization process. The algorithms are optimized and calibrated on data, using [Formula: see text] decays from [Formula: see text] collision data collected by LHCb at centre-of-mass energies of 7 and 8 TeV . The tagging power of the new pion algorithm is 60% greater than the previously available one; the algorithm using protons to identify the flavour of a [Formula: see text] meson is the first of its kind.

Measurement of pion, kaon and proton production in proton-proton collisions at [Formula: see text] TeV.

Science.gov (United States)

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The measurement of primary [Formula: see text], [Formula: see text], [Formula: see text] and [Formula: see text] production at mid-rapidity ([Formula: see text] 0.5) in proton-proton collisions at [Formula: see text][Formula: see text] 7 TeV performed with a large ion collider experiment at the large hadron collider (LHC) is reported. Particle identification is performed using the specific ionisation energy-loss and time-of-flight information, the ring-imaging Cherenkov technique and the kink-topology identification of weak decays of charged kaons. Transverse momentum spectra are measured from 0.1 up to 3 GeV/[Formula: see text] for pions, from 0.2 up to 6 GeV/[Formula: see text] for kaons and from 0.3 up to 6 GeV/[Formula: see text] for protons. The measured spectra and particle ratios are compared with quantum chromodynamics-inspired models, tuned to reproduce also the earlier measurements performed at the LHC. Furthermore, the integrated particle yields and ratios as well as the average transverse momenta are compared with results at lower collision energies.

Algorithm aversion: people erroneously avoid algorithms after seeing them err.

Science.gov (United States)

Dietvorst, Berkeley J; Simmons, Joseph P; Massey, Cade

2015-02-01

Research shows that evidence-based algorithms more accurately predict the future than do human forecasters. Yet when forecasters are deciding whether to use a human forecaster or a statistical algorithm, they often choose the human forecaster. This phenomenon, which we call algorithm aversion, is costly, and it is important to understand its causes. We show that people are especially averse to algorithmic forecasters after seeing them perform, even when they see them outperform a human forecaster. This is because people more quickly lose confidence in algorithmic than human forecasters after seeing them make the same mistake. In 5 studies, participants either saw an algorithm make forecasts, a human make forecasts, both, or neither. They then decided whether to tie their incentives to the future predictions of the algorithm or the human. Participants who saw the algorithm perform were less confident in it, and less likely to choose it over an inferior human forecaster. This was true even among those who saw the algorithm outperform the human.

Sensing of DNA by Graphene-on-Silicon FET Structures at DC and 101 GHz

Science.gov (United States)

2015-01-01

is just DIDC= Irms ¼ jIN I0j= Irms where Irms is the rms fluctuation dominated by a fast (white noise) component from the current source (Keithley 2400...and a slow (drift) component from the graphene. The noise was observed over a 600 s time span with the graphene kept dry, and yielded Irms 8:5

FROM THE HISTORY OF PIANO EDUCATION IN BESSARABIA OF THE 1900-1930s: THE MUSIC COLLEGE AT THE CHISINAU BRANCH OF THE I.R.M.S.

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MELNIC TAMARA

2015-06-01

Full Text Available At the beginning of professional musical education in Bessarabia in the 19th century, piano, more than other musical instrument, contributed to the aesthetic and artistic education of a wide range of the Bessarabian society. The appearance of the section of the I.R.M.S. in Chisinau and later — the Music College as a branch of this organization, allowed it to become one of the most musically developed cities from the South East of the Russian Empire. On the basis of the documents found in the National Archives (particularly „The Music School Programme in special and compulsory piano”, the newspapers of that time, works of V. Gutor and V. Buliciov, the author of the article considers the 30-year activity of the given educational organization, which proclaimed by its existence the end of the „epoch of dilettantism” and raised local musical education to a new level which had great importance in the formation and further development of musical culture of the country.

The new high-resolution IRMS MAT253 ULTRA at Utrecht University

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Röckmann, Thomas; Hofmann, Magdalena; Paul, Dipayan; Popa, Elena; Adnew, Getachew

2017-04-01

In 2016, the new high-resolution, multi-collector isotope ratio mass spectrometer MAT253 ULTRA [1] was installed at Utrecht University. This instrument is designed to reach a mass resolving power of 20,000 to 40,000 (M/ΔM). The ion currents are detected with a variable multi-collector unit that allows to register up to 9 ion currents simultaneously with Faraday cups and ion counters. The width of the entrance slit can be varied between 5 and 250μm so that the instrument can be operated under low, medium and high mass resolution, and an optimum balance between resolution and sensitivity can be selected for the respective applications. The central field of application of the new IRMS at Utrecht University is the measurement of multiply substituted isotopologues (clumped isotopes) in atmospheric trace compounds (e.g. 13CDH3, 13C18O16O, 18O18O, 15N14N18O) [1-7]. It is known from thermodynamics that the zero point energy of a chemical bond usually decreases when multiple heavy isotopes clump together in a molecule, and this effect depends on temperature [7]. Therefore, the abundance of clumped isotopes can be used as temperature indicator under thermodynamical equilibrium conditions. However, in the atmosphere, many reactions are controlled kinetically. It has been shown recently for a few examples that negative clumping signatures (anti-clumping) can be produced under non-equilibrium conditions [3,4]. In addition, based on purely statistical reasons, anti-clumping signatures will be produced in any molecule that contains indistinguishable atoms, which originate from isotopically distinct reservoir [5,6]. Thus, the investigation of multiply substituted isotopologues is expected to generate novel isotope signatures that can complement conventional stable isotope analysis in atmospheric science. We will present data on the performance of the MAT 253 ULTRA instrument and first scientific applications to atmospheric research. 1. Eiler, J.M., et al., A high-resolution gas

Síndrome de Waardenburg: achados audiológicos em 2 irmãos Waardenburg's syndrome: audiological findings in 2 brothers

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Carlos Henrique F. Martins

2003-01-01

Full Text Available A síndrome de Waardenburg foi inicialmente descrita em 1951 por P.J. Waardenburg, como uma condição autossômica dominante que apresenta penetrância e expressividade variáveis de seus caracteres. Os sinais clínicos mais frequentes são: deslocamento lateral dos cantos internos dos olhos (telecanto, hiperplasia da porção medial dos supercílios (sinofris, base nasal proeminente e alargada, alterações na pigmentação da íris e da pele, surdez congênita, mecha branca frontal ou encanecimento precoce. Este estudo foi realizado em dois irmãos de uma família, que apresentavam características clínicas da síndrome de Waardenburg, entre elas a deficiência auditiva. Os pacientes foram submetidos à uma avaliação otorrinolaringológica, audiológica e genética.Waardenburg's Syndrome, first described in 1951 by P.J. Waardenburg, is an autossomal dominant condition with variable penetrance and expressivity of its features. The clinical signs are lateral displacement of the inner canthi of the eyes, confluent eyebrows, broad and prominent nasal root, pigmentation changes of the irises and skin, sensorineural deafness, white forelock or early graying of the hair. This study was based on two brothers who presented a typical clinical picture of Waardenburg's Syndrome, including hearing loss. Otolaryngological, audiological and genetical evaluations were conducted.

Relação de uso dos recursos naturais pelas comunidades do entorno de um fragmento florestal urbano no Parque Estadual Dois Irmãos, Recife – Pernambuco. Relation of use of natural resources by surrounding communities of an urban forest fragment in Dois Irmãos State Park, Recife – Pernambuco.

Directory of Open Access Journals (Sweden)

Diogenes José Gusmão COUTINHO

2012-12-01

Full Text Available O trabalho visa determinar as relações entre comunidades e vegetação do Parque Estadual Dois Irmãos, Recife – Pernambuco. Através de 50 entrevistas, foram investigados aspectos da percepção ambiental dos moradores das comunidades do entorno da floresta do Parque Estadual, percebendo seu modo de vida e sua relação com os recursos naturais. Foram registradas 88 espécies, nativas, cultivadas e introduzida, e dez animais foram citados para a área. As famílias com maior representatividade em número de espécies foram: Fabaceae (treze espécies, Lamiaceae (seis Anacardiaceae, Arecaceae e Cucurbitaceae (cinco, Anonaceae, Asteraceae, Euphorbiaceae, Myrtaceae e Poaceae (quatro. O uso alimentício ocorreu em 31,42% das espécies, seguido do uso medicinal (28,57%, comercial (14,28%, madeireiro (11,42%, tecnológico (9,52% e ornamental (4,76%. A vegetação nativa constitui uma fonte importante de recursos madeireiros e medicinais, mas é subutilizada como fonte de alimento. Os vegetais não têm grande relevância na atividade de comércio, servindo como complemento de renda para as famílias. As comunidades utilizam diferentes fontes vegetais para as categorias comércio, construção e tecnologia, decorrentes tanto das principais atividades que exercem seus moradores, como dos recursos naturais à sua disposição. O lixo, a falta de saneamento básico e alagamentos são os principais problemas enfrentados pelas comunidades. The study aims to determine the relationships between vegetation communities and the Dois Irmãos State Park, Recife – Pernambuco. Through 50 interviews, aspects of environmental perception of the residents of the communities surrounding the State Park wereinvestigated in order to find out their lifestyle and their relationship with natural resources.We recorded 88 species, native, cultivated and introduced and ten animals were reported for the area. Families with more representative number of species were Fabaceae

Measurement of ψ(2S) meson production in pp collisions at [Formula: see text].

Science.gov (United States)

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Elsby, D; Esperante Pereira, D; Falabella, A; Fanchini, E; Färber, C; Fardell, G; Farinelli, C; Farry, S; Fave, V; Fernandez Albor, V; Ferro-Luzzi, M; Filippov, S; Fitzpatrick, C; Fontana, M; Fontanelli, F; Forty, R; Francisco, O; Frank, M; Frei, C; Frosini, M; Furcas, S; Gallas Torreira, A; Galli, D; Gandelman, M; Gandini, P; Gao, Y; Garnier, J-C; Garofoli, J; Garra Tico, J; Garrido, L; Gascon, D; Gaspar, C; Gauld, R; Gauvin, N; Gersabeck, M; Gershon, T; Ghez, Ph; Gibson, V; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gordon, H; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hampson, T; Hansmann-Menzemer, S; Harji, R; Harnew, N; Harrison, J; Harrison, P F; Hartmann, T; He, J; Heijne, V; Hennessy, K; Henrard, P; Hernando Morata, J A; van Herwijnen, E; Hicks, E; Holubyev, K; Hopchev, P; Hulsbergen, W; Hunt, P; Huse, T; Huston, R S; Hutchcroft, D; Hynds, D; Iakovenko, V; Ilten, P; Imong, J; Jacobsson, R; Jaeger, A; Jahjah Hussein, M; Jans, E; Jansen, F; Jaton, P; Jean-Marie, B; Jing, F; John, M; Johnson, D; Jones, C R; Jost, B; Kaballo, M; Kandybei, S; Karacson, M; Karbach, T M; Keaveney, J; Kenyon, I R; Kerzel, U; Ketel, T; Keune, A; Khanji, B; Kim, Y M; Knecht, M; Koopman, R F; Koppenburg, P; Korolev, M; Kozlinskiy, A; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kruzelecki, K; Kucharczyk, M; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanciotti, E; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J-P; Lefèvre, R; Leflat, A; Lefrançois, J; Leroy, O; Lesiak, T; Li, L; Li Gioi, L; Lieng, M; Liles, M; Lindner, R; Linn, C; Liu, B; Liu, G; von Loeben, J; Lopes, J H; Lopez Asamar, E; Lopez-March, N; Lu, H; Luisier, J; Mac Raighne, A; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Magnin, J; Malde, S; Mamunur, R M D; Manca, G; Mancinelli, G; Mangiafave, N; Marconi, U; Märki, R; Marks, J; Martellotti, G; Martens, A; Martin, L; Martín Sánchez, A; Martinez Santos, D; Massafferri, A; Mathe, Z; Matteuzzi, C; Matveev, M; Maurice, E; Maynard, B; Mazurov, A; McGregor, G; McNulty, R; Meissner, M; Merk, M; Merkel, J; Messi, R; Miglioranzi, S; Milanes, D A; Minard, M-N; Molina Rodriguez, J; Monteil, S; Moran, D; Morawski, P; Mountain, R; Mous, I; Muheim, F; Müller, K; Muresan, R; Muryn, B; Muster, B; Musy, M; Mylroie-Smith, J; Naik, P; Nakada, T; Nandakumar, R; Nasteva, I; Nedos, M; Needham, M; Neufeld, N; Nguyen, A D; Nguyen-Mau, C; Nicol, M; Niess, V; Nikitin, N; Nomerotski, A; Novoselov, A; Oblakowska-Mucha, A; Obraztsov, V; Oggero, S; Ogilvy, S; Okhrimenko, O; Oldeman, R; Orlandea, M; Otalora Goicochea, J M; Owen, P; Pal, K; Palacios, J; Palano, A; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Parkes, C; Parkinson, C J; Passaleva, G; Patel, G D; Patel, M; Paterson, S K; Patrick, G N; Patrignani, C; Pavel-Nicorescu, C; Pazos Alvarez, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perego, D L; Perez Trigo, E; Pérez-Calero Yzquierdo, A; Perret, P; Perrin-Terrin, M; Pessina, G; Petrella, A; Petrolini, A; Phan, A; Picatoste Olloqui, E; Pie Valls, B; Pietrzyk, B; Pilař, T; Pinci, D; Plackett, R; Playfer, S; Plo Casasus, M; Polok, G; Poluektov, A; Polycarpo, E; Popov, D; Popovici, B; Potterat, C; Powell, A; Prisciandaro, J; Pugatch, V; Puig Navarro, A; Qian, W; Rademacker, J H; Rakotomiaramanana, B; Rangel, M S; Raniuk, I; Raven, G; Redford, S; Reid, M M; Dos Reis, A C; Ricciardi, S; Richards, A; Rinnert, K; Roa Romero, D A; Robbe, P; Rodrigues, E; Rodrigues, F; Rodriguez Perez, P; Rogers, G J; Roiser, S; Romanovsky, V; Rosello, M; Rouvinet, J; Ruf, T; Ruiz, H; Sabatino, G; Saborido Silva, J J; Sagidova, N; Sail, P; Saitta, B; Salzmann, C; Sannino, M; Santacesaria, R; Santamarina Rios, C; Santinelli, R; Santovetti, E; Sapunov, M; Sarti, A; Satriano, C; Satta, A; Savrie, M; Savrina, D; Schaack, P; Schiller, M; Schleich, S; Schlupp, M; Schmelling, M; Schmidt, B; Schneider, O; Schopper, A; Schune, M-H; Schwemmer, R; Sciascia, B; Sciubba, A; Seco, M; Semennikov, A; Senderowska, K; Sepp, I; Serra, N; Serrano, J; Seyfert, P; Shapkin, M; Shapoval, I; Shatalov, P; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, O; Shevchenko, V; Shires, A; Silva Coutinho, R; Skwarnicki, T; Smith, N A; Smith, E; Sobczak, K; Soler, F J P; Solomin, A; Soomro, F; Souza De Paula, B; Spaan, B; Sparkes, A; Spradlin, P; Stagni, F; Stahl, S; Steinkamp, O; Stoica, S; Stone, S; Storaci, B; Straticiuc, M; Straumann, U; Subbiah, V K; Swientek, S; Szczekowski, M; Szczypka, P; Szumlak, T; T'Jampens, S; Teodorescu, E; Teubert, F; Thomas, C; Thomas, E; van Tilburg, J; Tisserand, V; Tobin, M; Topp-Joergensen, S; Torr, N; Tournefier, E; Tourneur, S; Tran, M T; Tsaregorodtsev, A; Tuning, N; Ubeda Garcia, M; Ukleja, A; Urquijo, P; Uwer, U; Vagnoni, V; Valenti, G; Vazquez Gomez, R; Vazquez Regueiro, P; Vecchi, S; Velthuis, J J; Veltri, M; Viaud, B; Videau, I; Vieira, D; Vilasis-Cardona, X; Visniakov, J; Vollhardt, A; Volyanskyy, D; Voong, D; Vorobyev, A; Voss, H; Wandernoth, S; Wang, J; Ward, D R; Watson, N K; Webber, A D; Websdale, D; Whitehead, M; Wiedner, D; Wiggers, L; Wilkinson, G; Williams, M P; Williams, M; Wilson, F F; Wishahi, J; Witek, M; Witzeling, W; Wotton, S A; Wyllie, K; Xie, Y; Xing, F; Xing, Z; Yang, Z; Young, R; Yushchenko, O; Zangoli, M; Zavertyaev, M; Zhang, F; Zhang, L; Zhang, W C; Zhang, Y; Zhelezov, A; Zhong, L; Zvyagin, A

The differential cross-section for the inclusive production of ψ (2 S ) mesons in pp collisions at [Formula: see text] has been measured with the LHCb detector. The data sample corresponds to an integrated luminosity of 36 pb -1 . The ψ (2 S ) mesons are reconstructed in the decay channels ψ (2 S )→ μ + μ - and ψ (2 S )→ J / ψπ + π - , with the J / ψ meson decaying into two muons. Results are presented both for promptly produced ψ (2 S ) mesons and for those originating from b -hadron decays. In the kinematic range p T ( ψ (2 S ))≤16 GeV/ c and 2< y ( ψ (2 S ))≤4.5 we measure [Formula: see text] where the last uncertainty on the prompt cross-section is due to the unknown ψ (2 S ) polarization. Recent QCD calculations are found to be in good agreement with our measurements. Combining the present result with the LHCb J / ψ measurements we determine the inclusive branching fraction [Formula: see text] where the last uncertainty is due to the [Formula: see text], [Formula: see text] and [Formula: see text] branching fraction uncertainties.

Departments as Agents of Change

Science.gov (United States)

Lagowski, J. J.

1996-07-01

Higher education is changing because it has no choice. And, for the most part, outside influences are dictating the processes of change. The more fortunate institutions have had a flat budget during this period, but most have been forced to deal with a declining revenue stream as well. Legislators seem bent on micromanaging state-supported institutions, even as they cut their support. Regulators demand greater institutional accountability. Students and their parents expect more service at lower prices and increased flexibility. Technological advances have dramatically affected the availability and accessibility of extant knowledge. It is no longer a question of whether institutions will change, but rather, who will control the change. Most institutions possess long-standing academic traditions, but these are placed at risk in an increasingly competitive market that holds little sympathy for such traditions and may even see them as obstacles or barriers. As a result, the change agents will undoubtedly have a profound effect on the very nature of academic institutions. From the academic point of view, it would seem prudent to attempt to manage the changes that will inevitably occur. A number of concerned observers, notably the Pew Higher Education Roundtable and the American Association for Higher Education, argue persuasively that the academic department is the logical focus for responding to the current winds of change. Using a marketing metaphor, the academic department has been likened to a "producers' cooperative" of services that consumers seek. Thus, the department should be held accountable for the quality of teaching delivered by its members, for the coherence of its major, for its contributions to the general education curriculum, and for supervising and rewarding its individual faculty members. If departments are to be held accountable, it is surely in their best interest to act in such a way that they are accountable. Expecting academic departments to be

Department of Training and Consulting: Overview

International Nuclear Information System (INIS)

Dobrzynski, L.

2004-01-01

Full text: The department of Training and Consulting is regularly serving secondary schools' pupils and teachers, university students and the public. The year 2003 set up a new record: the Department accepted a bout 7000 visitors, about 2000 more than during 2002. A truly great event was the opening of the permanent exhibition displaying the model of nuclear power plant originally planned to be built in Zarnowiec near Gdansk. The opening was combined with a short symposium on the ''Nuclear Physics and Technology - Today and Tomorrow's Social Education in European Union''. The opening was visited by many prominent guests from Polish Atomic Agency, local governments, universities and institutes. In addition, the Department participated in the organization of a symposium dedicated to the 100 th Anniversary of the first Nobel Prize awarded to Marie Curie-Sklodowska. This was also an occasion for a small exhibition based on photographs and exhibits borrowed from the Maria Curie-Sklodowska Museum in Warsaw, which was co-organiser of the symposium. The main organizer and proposer of the symposium was a social organization, the Interschool Committee of Promotion of the Educational Undertakings ''Europe 2000'', which promotes educational initiatives for the youth from Otwock, a town near to Swierk. It was our pleasure that our Department was chosen as the place for the organization of this symposium in which the best pupils, local authorities from Otwock, and sponsors of the activity of the aforementioned group were present. On the 15 th of October we celebrated the 5 th anniversary of our educational activity that started with the opening of the exhibition on ''Nuclear wastes: problems, solutions''. The exhibition is still displayed and attracts attention. It is a real pleasure to see how much the interest in our activity has grown through all those years. On the other hand, the educational efforts of the Department turned out to be worth our labor: in the all

Scholars See Comics as No Laughing Matter

Science.gov (United States)

Viadero, Debra

2009-01-01

Once fuel for mass book burnings, comic books are gaining a foothold in the nation's schools, with teachers seeing them as a learning tool and scholars viewing them as a promising subject for educational research. Evidence of the rising credibility of Spiderman, Batman, and Archie came last month when Fordham University's graduate school of…

Influence of seeing effects on cloud model inversions

Czech Academy of Sciences Publication Activity Database

Tziotziou, K.; Heinzel, Petr; Tsiropoula, G.

2007-01-01

Roč. 472, č. 1 (2007), s. 287-292 ISSN 0004-6361 Institutional research plan: CEZ:AV0Z10030501 Keywords : cloud model * inversions * seeing effects Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics Impact factor: 4.259, year: 2007

Search for charged Higgs bosons in e+e- collisions at [Formula: see text].

Science.gov (United States)

Abbiendi, G; Ainsley, C; Åkesson, P F; Alexander, G; Anagnostou, G; Anderson, K J; Asai, S; Axen, D; Bailey, I; Barberio, E; Barillari, T; Barlow, R J; Batley, R J; Bechtle, P; Behnke, T; Bell, K W; Bell, P J; Bella, G; Bellerive, A; Benelli, G; Bethke, S; Biebel, O; Boeriu, O; Bock, P; Boutemeur, M; Braibant, S; Brown, R M; Burckhart, H J; Campana, S; Capiluppi, P; Carnegie, R K; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Ciocca, C; Csilling, A; Cuffiani, M; Dado, S; Dallavalle, M; De Roeck, A; De Wolf, E A; Desch, K; Dienes, B; Dubbert, J; Duchovni, E; Duckeck, G; Duerdoth, I P; Etzion, E; Fabbri, F; Ferrari, P; Fiedler, F; Fleck, I; Ford, M; Frey, A; Gagnon, P; Gary, J W; Geich-Gimbel, C; Giacomelli, G; Giacomelli, P; Giunta, M; Goldberg, J; Gross, E; Grunhaus, J; Gruwé, M; Gupta, A; Hajdu, C; Hamann, M; Hanson, G G; Harel, A; Hauschild, M; Hawkes, C M; Hawkings, R; Herten, G; Heuer, R D; Hill, J C; Hoffman, K; Horváth, D; Igo-Kemenes, P; Ishii, K; Jeremie, H; Jovanovic, P; Junk, T R; Kanzaki, J; Karlen, D; Kawagoe, K; Kawamoto, T; Keeler, R K; Kellogg, R G; Kennedy, B W; Kluth, S; Kobayashi, T; Kobel, M; Komamiya, S; Krämer, T; Krasznahorkay, A; Krieger, P; von Krogh, J; Kuhl, T; Kupper, M; Lafferty, G D; Landsman, H; Lanske, D; Lellouch, D; Letts, J; Levinson, L; Lillich, J; Lloyd, S L; Loebinger, F K; Lu, J; Ludwig, A; Ludwig, J; Mader, W; Marcellini, S; Marchant, T E; Martin, A J; Mashimo, T; Mättig, P; McKenna, J; McPherson, R A; Meijers, F; Menges, W; Merritt, F S; Mes, H; Meyer, N; Michelini, A; Mihara, S; Mikenberg, G; Miller, D J; Mohr, W; Mori, T; Mutter, A; Nagai, K; Nakamura, I; Nanjo, H; Neal, H A; O'Neale, S W; Oh, A; Okpara, A; Oreglia, M J; Orito, S; Pahl, C; Pásztor, G; Pater, J R; Pilcher, J E; Pinfold, J; Plane, D E; Pooth, O; Przybycień, M; Quadt, A; Rabbertz, K; Rembser, C; Renkel, P; Roney, J M; Rossi, A M; Rozen, Y; Runge, K; Sachs, K; Saeki, T; Sarkisyan, E K G; Schaile, A D; Schaile, O; Scharff-Hansen, P; Schieck, J; Schörner-Sadenius, T; Schröder, M; Schumacher, M; Seuster, R; Shears, T G; Shen, B C; Sherwood, P; Skuja, A; Smith, A M; Sobie, R; Söldner-Rembold, S; Spano, F; Stahl, A; Strom, D; Ströhmer, R; Tarem, S; Tasevsky, M; Teuscher, R; Thomson, M A; Torrence, E; Toya, D; Trigger, I; Trócsányi, Z; Tsur, E; Turner-Watson, M F; Ueda, I; Ujvári, B; Vollmer, C F; Vannerem, P; Vértesi, R; Verzocchi, M; Voss, H; Vossebeld, J; Ward, C P; Ward, D R; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wengler, T; Wermes, N; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Zer-Zion, D; Zivkovic, L

A search is made for charged Higgs bosons predicted by Two-Higgs-Doublet extensions of the Standard Model (2HDM) using electron-positron collision data collected by the OPAL experiment at [Formula: see text], corresponding to an integrated luminosity of approximately 600 pb -1 . Charged Higgs bosons are assumed to be pair-produced and to decay into [Formula: see text], τν τ or AW ± . No signal is observed. Model-independent limits on the charged Higgs-boson production cross section are derived by combining these results with previous searches at lower energies. Under the assumption [Formula: see text], motivated by general 2HDM type II models, excluded areas on the [Formula: see text] plane are presented and charged Higgs bosons are excluded up to a mass of 76.3 GeV at 95 % confidence level, independent of the branching ratio BR(H ± → τν τ ). A scan of the 2HDM type I model parameter space is performed and limits on the Higgs-boson masses [Formula: see text] and m A are presented for different choices of tan β .

Department of Particle Theory - Overview

International Nuclear Information System (INIS)

Jezabek, M.

1999-01-01

Full text: Research performed at the Department of Particle Theory is devoted to fundamental particles and their interactions. These studies are closely related to the current and future high energy experiments at e + e - and hadron-hadron colliders: LEP, TESLA, Tevatron and LHC. The papers reported below cover a wide range of particle physics from neutrino masses and oscillations to processes involving heavy particles like gauge and Higgs bosons or the top quark. An evidence of neutrino oscillations observed by the SuperKamiokande Collaboration was the most spectacular discovery of the year 1998. In a theoretical investigation performed at our department a relation has been found between the so called see-saw mechanism and the bi-maximal neutrino mixing. Since many years a very important and labour-consuming part of the research activities is related to precision tests of the Standard Model. In the last year successful runs of LEP2 stimulated an impressive progress in theoretical description of processes with two- and four-fermion final states in electron-positron annihilation. It is worth stressing that the results of the calculations have been distributed in the form of the computer programs (Monte Carlo and other types) which serve as an indispensable tool in the analysis of the experimental data. Although the whole scientific program is a natural continuation of the activities started earlier a few results obtained in the last year should be mentioned: Publication of the four-fermion Monte Carlo program KORALW for high energy e + e - colliders; Development of the exponentiation scheme at the spin amplitude level and studies of the anomalous couplings for the e + e - → f (anti)f (nγ) processes; Relation between QCD static potentials in momentum and position spaces, and its consequences for bottom and top quark pair production and spectroscopy; Participation in the preparation of the physics program of the pp experiments on LHC collider particularly for Higgs

See it with feeling: affective predictions during object perception

Science.gov (United States)

Barrett, L.F.; Bar, Moshe

2009-01-01

People see with feeling. We ‘gaze’, ‘behold’, ‘stare’, ‘gape’ and ‘glare’. In this paper, we develop the hypothesis that the brain's ability to see in the present incorporates a representation of the affective impact of those visual sensations in the past. This representation makes up part of the brain's prediction of what the visual sensations stand for in the present, including how to act on them in the near future. The affective prediction hypothesis implies that responses signalling an object's salience, relevance or value do not occur as a separate step after the object is identified. Instead, affective responses support vision from the very moment that visual stimulation begins. PMID:19528014

Ground Penetrating Radar, Magnetic and Compositional Analysis of Sediment Cores and Surface Samples: The Relationships Between Lacustrine Sediments and Holocene Lake- Level and Climate Change at Deming Lake, Minnesota, USA

Science.gov (United States)

Murray, R.; Lascu, I.; Plank, C.

2007-12-01

Deming Lake is a small (Deming. Cores were sampled continuously at a 1-2 cm resolution and sediment composition (in terms of percent organic matter, carbonate material, and minerogenic residue) was determined via loss on ignition (LOI). Isothermal remanent magnetization (IRM) and anhysteretic remanent magnetization (ARM) were used as proxies of magnetic mineral concentration and grain size. Four lithostratigraphic units were identified and correlated between cores based on these analyses. Changes in GPR facies corroborate the correlation between the two shallow cores. In order to inform our interpretation of down-core variations in magnetic properties and LOI values in terms of variations in lake depth, a suite of over 70 modern sediment samples were collected from the basin and analyzed. LOI compositional variability across the basin was high, with no clear trends related to depth or distance from shore. A sharp decrease in minerogenic content was observed at depths consistent with a predicted wave-base of 0.5 m, but aside from this trend it appears the steep slopes of much of the basin promote gravity driven slumping and mixing of sediments at depth. In the profundal sediments IRM values are routinely 5% higher than in the slope and littoral environments, while ARM/IRM ratios indicate an increase in magnetic grain size with water depth. We infer that an increase in coarse organic material in the shallow-water cores of Deming records a period of aridity (associated with a decrease lake-level less than 2m based on GPR profiles) and/or increased water clarity during the regionally expansive mid-Holocene dry period. We do not see clear evidence of late-Holocene lake level change of a significant magnitude (i.e. >1m). While remanence measurements (especially IRM) often correlate with the LOI residue, interference in the IRM resulting from the dissolution of magnetic minerals casts uncertainty into the reliability of our magnetic measurements as a signal of climate

A see-saw scenario of an $A_4$ flavour symmetric standard model

CERN Document Server

Dinh, Dinh Nguyen; Văn, Phi Quang; Vân, Nguyen Thi Hông

2016-01-01

A see-saw scenario for an $A_4$ flavour symmetric standard model is presented. As before, the see-saw mechanism can be realized in several models of different types depending on different ways of neutrino mass generation corresponding to the introduction of new fields with different symmetry structures. In the present paper, a general desription of all these see-saw types is made with a more detailed investigation on type-I models. As within the original see-saw mechanism, the symmetry structure of the standard model fields decides the number and the symmetry structure of the new fields. In a model considered here, the scalar sector consists of three standard-model-Higgs-like iso-doublets ($SU_L(2)$-doublets) forming an $A_4$ triplet. The latter is a superposition of three mass-eigen states, one of which could be identified with the recently discovered Higgs boson. A possible relation to the still-deliberated 750 GeV diphoton resonance at the 13 TeV LHC collisions is also discussed. In the lepton sector, the ...

Resources from waste peer reviews : peer reviews and responses

Energy Technology Data Exchange (ETDEWEB)

McNeill, C.I. [United Nations Development Programme, New York, NY (United States). Environment and Energy Group; Hamilton, D.A. [Lewis and Zimmerman Associates Inc., Tacoma, WA (United States); Nilsen, C. [Altus Group, Vancouver, BC (Canada); Dawson, R.N. [Stantec Consulting Ltd., Surrey, BC (Canada)

2008-02-29

The Resources from Waste Integrated Resource Management (IRM) study was commissioned by the British Columbia Ministry of Community Services to examine the feasibility of using solid and liquid waste to create energy, reduce greenhouse gas emissions, conserve water and recover nutrients. The Ministry of Community Services wanted to know if IRM could be applied province-wide as well as to the Capital Region District (CRD). The study assessed the potential contribution that the IRM approach can make to achieve the province's climate change agenda and Green Cities Program. This document provided comments on the IRM study report by 4 peer reviewers who generally agreed about the usefulness of the IRM concept. However, there were differences of opinion about how best to apply the concept and about potential costs and revenues. IRM is a concept and process that mimics ecological cycles of reuse and offers a means to address future challenges regarding climate change and population growth. In its optimal deployment, IRM can potentially result in zero waste. The reviewers indicated that IRM has the potential to be a viable solution to water, solid and liquid waste management that should be less expensive, result in fewer environmental impacts, and provide greater flexibility than traditional approaches to waste management. The advent of a graduated carbon tax on fossil based fuels will add value over time to the IRM model because it can generate significant amounts of non-fossil-based energy sources and contribute to GHG reduction targets. All the technologies presented in the IRM study are well-established, currently operational and in use in various jurisdictions. It was concluded, however, that further work is needed to evaluate IRM before it can be adopted without reservation. refs.

Seeing Clearly (A Cup of Health with CDC)

Centers for Disease Control (CDC) Podcasts

If you’re not seeing the world as clearly as you used to, you might be among the millions of people suffering from vision impairment. In this podcast, Dr. John Crews discusses ways to take care of your eyes.

Managing an imaging department with a business perspective. A view from the other side.

Science.gov (United States)

Merriam, J

1999-01-01

I came to the position of director of radiology at Winchester Hospital with two advanced degrees, in business administration and in health-care administration, to replace a director of 35 years, who had come from a technical background. That this community hospital outside Boston nourishes the entrepreneurial spirit is one of the premises underlying its success. I was supported from the beginning both by the radiologists, who supported the concept of a business-person running the department, and by the manager, whose acceptance of my role helped set the tone for the department. My goal was to create a vision for the department, which I could do only by establishing a relationship with the supervisory staff. Communication became my greatest challenge: to listen and learn from my staff and to articulate how we could move to a new level of performance. My management philosophy included giving budget responsibility to the supervisors, to teach how revenue and expense directly impact the department's business. We learned together the importance of customer service and how it, too, could impact our business. Finally, I helped supervisors offer their own ideas to solve department problems. Joining the AHRA, reading its publications and attending its conferences have helped me gain a broader perspective of the industry. Now, I see my role as a facilitator who sets a vision for the department and provides the proper support, tools and guidance for the staff to achieve results. Together, we have created a successful balance between the business and the patient care components.

Sample Exchange Evaluation (SEE) Report - Phase II

Energy Technology Data Exchange (ETDEWEB)

Winters, W.I.

1994-09-28

This report describes the results from Phase II of the Sample Exchange Evaluation (SEE) Program, a joint effort to compare analytical laboratory performance on samples from the Hanford Site`s high-level waste tanks. In Phase II, the program has been expanded to include inorganic constituents in addition to radionuclides. Results from Phase II that exceeded 20% relative percent difference criteria are identified.

Sample Exchange Evaluation (SEE) Report - Phase II

International Nuclear Information System (INIS)

Winters, W.I.

1994-01-01

This report describes the results from Phase II of the Sample Exchange Evaluation (SEE) Program, a joint effort to compare analytical laboratory performance on samples from the Hanford Site's high-level waste tanks. In Phase II, the program has been expanded to include inorganic constituents in addition to radionuclides. Results from Phase II that exceeded 20% relative percent difference criteria are identified

See me through my eyes

Science.gov (United States)

Poorthuis, Astrid M. G.; Hutteman, Roos; Asendorpf, Jens B.; Denissen, Jaap J. A.; van Aken, Marcel A. G.

2017-01-01

Achieving a clear view of one’s personality is a challenging but crucial developmental task during adolescence, which has enduring influences. This task might be harder if significant others see individuals differently from how the adolescents see themselves. Supporting this, the looking-glass-self theory suggests that significant others constitute a social mirror into which the individual gazes to form his/her self-view. The present study was the first to longitudinally examine whether self–other agreement in personality during adolescence (i.e., self–parent and self–friend agreement at age 12 and self–mother and self–father agreement at age 17) promote self-esteem development from age 17 to 29 years (N =186, 53% boys). Results for girls consistently confirmed the hypothesized beneficial effect of self–parent agreement, while the picture was more complicated for boys. That is, for girls, self–parent agreement at age 12 and age 17 both predicted steeper increases in self-esteem. For boys, steeper self-esteem development was predicted by higher self–parent agreement at age 12, but unexpectedly, also by lower self–parent agreement at age 17. All these results remained after controlling for (self-rated) personality. Moreover, self–friend agreement did not show any effects on self-esteem development, suggesting that the influence of peers’ convergence with self-views during early adolescence may not be as prominent as parents’. Results are discussed from the perspective of self-view formation and maintenance during adolescence and young adulthood. The present study sheds light on the longitudinal effect of one’s own view of personality being shared by important others on self-esteem development. PMID:29276319

Improvement of robustness of optical see-through AR for a remote maintenance support system

International Nuclear Information System (INIS)

Nagamatsu, Takashi; Kaieda, Yohei; Kitagawa, Yuki; Shimada, Hiroyuki; Otsuji, Tomoo; Yoshikawa, Hidekazu

2005-01-01

A remote maintenance support system using optical see-through AR has been developed to keep safety and reliability in preparation for old experts' retirement. It enables plant workers to collaborate with a remote expert (supervisor) by using a wearable computer, an optical see-through AR (Augmented Reality) technology and eye-gaze information. The optical see-through AR enables a user to see the real world through a transparent display and it contributes to keeping safety of plant workers and acquiring detail information of machines. On the contrary, the registration between computer-generated objects and the real world is difficult, so we developed a method to correct the geometrical consistency for practical use of optical see-through AR. The developed method has two steps: (1) detection of the shift amount of HMD by the eye camera image and (2) adjustment of the display position on the HMD screen. This method made it possible to allow user's moving and physical shift of HMD, so it is capable of wide application to practical works

Boosting Higgs pair production in the [Formula: see text] final state with multivariate techniques.

Science.gov (United States)

Behr, J Katharina; Bortoletto, Daniela; Frost, James A; Hartland, Nathan P; Issever, Cigdem; Rojo, Juan

2016-01-01

The measurement of Higgs pair production will be a cornerstone of the LHC program in the coming years. Double Higgs production provides a crucial window upon the mechanism of electroweak symmetry breaking and has a unique sensitivity to the Higgs trilinear coupling. We study the feasibility of a measurement of Higgs pair production in the [Formula: see text] final state at the LHC. Our analysis is based on a combination of traditional cut-based methods with state-of-the-art multivariate techniques. We account for all relevant backgrounds, including the contributions from light and charm jet mis-identification, which are ultimately comparable in size to the irreducible 4 b QCD background. We demonstrate the robustness of our analysis strategy in a high pileup environment. For an integrated luminosity of [Formula: see text] ab[Formula: see text], a signal significance of [Formula: see text] is obtained, indicating that the [Formula: see text] final state alone could allow for the observation of double Higgs production at the High Luminosity LHC.

Bug bites and stings: When to see a dermatologist

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Full Text Available ... Contagious skin diseases Cosmetic treatments Dry / sweaty skin Eczema / dermatitis Hair and scalp problems Itchy skin Painful skin / joints Rashes Scaly skin Skin cancer Why see a board- ...

Measurement of the phase difference between short- and long-distance amplitudes in the [Formula: see text] decay.

Science.gov (United States)

Aaij, R; Adeva, B; Adinolfi, M; Ajaltouni, Z; Akar, S; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amerio, S; Amhis, Y; An, L; Anderlini, L; Andreassi, G; Andreotti, M; Andrews, J E; Appleby, R B; Archilli, F; d'Argent, P; Arnau Romeu, J; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Babuschkin, I; Bachmann, S; Back, J J; Badalov, A; Baesso, C; Baker, S; Balagura, V; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Baszczyk, M; Batozskaya, V; Batsukh, B; Battista, V; Bay, A; Beaucourt, L; Beddow, J; Bedeschi, F; Bediaga, I; Bel, L J; Bellee, V; Belloli, N; Belous, K; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Berezhnoy, A; Bernet, R; Bertolin, A; Betancourt, C; Betti, F; Bettler, M-O; van Beuzekom, M; Bezshyiko, Ia; Bifani, S; Billoir, P; Bird, T; Birnkraut, A; Bitadze, A; Bizzeti, A; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Boettcher, T; Bondar, A; Bondar, N; Bonivento, W; Bordyuzhin, I; Borgheresi, A; Borghi, S; Borisyak, M; Borsato, M; Bossu, F; Boubdir, M; Bowcock, T J V; Bowen, E; Bozzi, C; Braun, S; Britsch, M; Britton, T; Brodzicka, J; Buchanan, E; Burr, C; Bursche, A; Buytaert, J; Cadeddu, S; Calabrese, R; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Campora Perez, D H; Capriotti, L; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carniti, P; Carson, L; Carvalho Akiba, K; Casse, G; Cassina, L; Castillo Garcia, L; Cattaneo, M; Cavallero, G; Cenci, R; Chamont, D; Charles, M; Charpentier, Ph; Chatzikonstantinidis, G; Chefdeville, M; Chen, S; Cheung, S-F; Chobanova, V; Chrzaszcz, M; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coco, V; Cogan, J; Cogneras, E; Cogoni, V; Cojocariu, L; Collazuol, G; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coombs, G; Coquereau, S; Corti, G; Corvo, M; Costa Sobral, C M; Couturier, B; Cowan, G A; Craik, D C; Crocombe, A; Cruz Torres, M; Cunliffe, S; Currie, R; D'Ambrosio, C; Da Cunha Marinho, F; Dall'Occo, E; Dalseno, J; David, P N Y; Davis, A; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Serio, M; De Simone, P; Dean, C-T; Decamp, D; Deckenhoff, M; Del Buono, L; Demmer, M; Dendek, A; Derkach, D; Deschamps, O; Dettori, F; Dey, B; Di Canto, A; Dijkstra, H; Dordei, F; Dorigo, M; Dosil Suárez, A; Dovbnya, A; Dreimanis, K; Dufour, L; Dujany, G; Dungs, K; Durante, P; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Déléage, N; Easo, S; Ebert, M; Egede, U; Egorychev, V; Eidelman, S; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; Ely, S; Esen, S; Evans, H M; Evans, T; Falabella, A; Farley, N; Farry, S; Fay, R; Fazzini, D; Ferguson, D; Fernandez Prieto, A; Ferrari, F; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fini, R A; Fiore, M; Fiorini, M; Firlej, M; Fitzpatrick, C; Fiutowski, T; Fleuret, F; Fohl, K; Fontana, M; Fontanelli, F; Forshaw, D C; Forty, R; Franco Lima, V; Frank, M; Frei, C; Fu, J; Funk, W; Furfaro, E; Färber, C; Gallas Torreira, A; Galli, D; Gallorini, S; Gambetta, S; Gandelman, M; Gandini, P; Gao, Y; Garcia Martin, L M; García Pardiñas, J; Garra Tico, J; Garrido, L; Garsed, P J; Gascon, D; Gaspar, C; Gavardi, L; Gazzoni, G; Gerick, D; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gianì, S; Gibson, V; Girard, O G; Giubega, L; Gizdov, K; Gligorov, V V; Golubkov, D; Golutvin, A; Gomes, A; Gorelov, I V; Gotti, C; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graverini, E; Graziani, G; Grecu, A; Griffith, P; Grillo, L; Gruberg Cazon, B R; Grünberg, O; Gushchin, E; Guz, Yu; Gys, T; Göbel, C; Hadavizadeh, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hall, S; Hamilton, B; Han, X; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; Hatch, M; He, J; Head, T; Heister, A; Hennessy, K; Henrard, P; Henry, L; van Herwijnen, E; Heß, M; Hicheur, A; Hill, D; Hombach, C; Hopchev, H; Hulsbergen, W; Humair, T; Hushchyn, M; Hutchcroft, D; Idzik, M; Ilten, P; Jacobsson, R; Jaeger, A; Jalocha, J; Jans, E; Jawahery, A; Jiang, F; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Jurik, N; Kandybei, S; Karacson, M; Kariuki, J M; Karodia, S; Kecke, M; Kelsey, M; Kenzie, M; Ketel, T; Khairullin, E; Khanji, B; Khurewathanakul, C; Kirn, T; Klaver, S; Klimaszewski, K; Koliiev, S; Kolpin, M; Komarov, I; Koopman, R F; Koppenburg, P; Kosmyntseva, A; Kozachuk, A; Kozeiha, M; Kravchuk, L; Kreplin, K; Kreps, M; Krokovny, P; Kruse, F; Krzemien, W; Kucewicz, W; Kucharczyk, M; Kudryavtsev, V; Kuonen, A K; Kurek, K; Kvaratskheliya, T; Lacarrere, D; Lafferty, G; Lai, A; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Leflat, A; Lefrançois, J; Lefèvre, R; Lemaitre, F; Lemos Cid, E; Leroy, O; Lesiak, T; Leverington, B; Li, T; Li, Y; Likhomanenko, T; Lindner, R; Linn, C; Lionetto, F; Liu, X; Loh, D; Longstaff, I; Lopes, J H; Lucchesi, D; Lucio Martinez, M; Luo, H; Lupato, A; Luppi, E; Lupton, O; Lusiani, A; Lyu, X; Machefert, F; Maciuc, F; Maev, O; Maguire, K; Malde, S; Malinin, A; Maltsev, T; Manca, G; Mancinelli, G; Manning, P; Maratas, J; Marchand, J F; Marconi, U; Marin Benito, C; Marinangeli, M; Marino, P; Marks, J; Martellotti, G; Martin, M; Martinelli, M; Martinez Santos, D; Martinez Vidal, F; Martins Tostes, D; Massacrier, L M; Massafferri, A; Matev, R; Mathad, A; Mathe, Z; Matteuzzi, C; Mauri, A; Maurice, E; Maurin, B; Mazurov, A; McCann, M; McNab, A; McNulty, R; Meadows, B; Meier, F; Meissner, M; Melnychuk, D; Merk, M; Merli, A; Michielin, E; Milanes, D A; Minard, M-N; Mitzel, D S; Mogini, A; Molina Rodriguez, J; Monroy, I A; Monteil, S; Morandin, M; Morawski, P; Mordà, A; Morello, M J; Morgunova, O; Moron, J; Morris, A B; Mountain, R; Muheim, F; Mulder, M; Mussini, M; Müller, D; Müller, J; Müller, K; Müller, V; Naik, P; Nakada, T; Nandakumar, R; Nandi, A; Nasteva, I; Needham, M; Neri, N; Neubert, S; Neufeld, N; Neuner, M; Nguyen, T D; Nguyen-Mau, C; Nieswand, S; Niet, R; Nikitin, N; Nikodem, T; Nogay, A; Novoselov, A; O'Hanlon, D P; Oblakowska-Mucha, A; Obraztsov, V; Ogilvy, S; Oldeman, R; Onderwater, C J G; Otalora Goicochea, J M; Otto, A; Owen, P; Oyanguren, A; Pais, P R; Palano, A; Palombo, F; Palutan, M; Papanestis, A; Pappagallo, M; Pappalardo, L L; Parker, W; Parkes, C; Passaleva, G; Pastore, A; Patel, G D; Patel, M; Patrignani, C; Pearce, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perret, P; Pescatore, L; Petridis, K; Petrolini, A; Petrov, A; Petruzzo, M; Picatoste Olloqui, E; Pietrzyk, B; Pikies, M; Pinci, D; Pistone, A; Piucci, A; Placinta, V; Playfer, S; Plo Casasus, M; Poikela, T; Polci, F; Poluektov, A; Polyakov, I; Polycarpo, E; Pomery, G J; Popov, A; Popov, D; Popovici, B; Poslavskii, S; Potterat, C; Price, E; Price, J D; Prisciandaro, J; Pritchard, A; Prouve, C; Pugatch, V; Puig Navarro, A; Punzi, G; Qian, W; Quagliani, R; Rachwal, B; Rademacker, J H; Rama, M; Ramos Pernas, M; Rangel, M S; Raniuk, I; Ratnikov, F; Raven, G; Redi, F; Reichert, S; Dos Reis, A C; Remon Alepuz, C; Renaudin, V; Ricciardi, S; Richards, S; Rihl, M; Rinnert, K; Rives Molina, V; Robbe, P; Rodrigues, A B; Rodrigues, E; Rodriguez Lopez, J A; Rodriguez Perez, P; Rogozhnikov, A; Roiser, S; Rollings, A; Romanovskiy, V; Romero Vidal, A; Ronayne, J W; Rotondo, M; Rudolph, M S; Ruf, T; Ruiz Valls, P; Saborido Silva, J J; Sadykhov, E; Sagidova, N; Saitta, B; Salustino Guimaraes, V; Sanchez Mayordomo, C; Sanmartin Sedes, B; Santacesaria, R; Santamarina Rios, C; Santimaria, M; Santovetti, E; Sarti, A; Satriano, C; Satta, A; Saunders, D M; Savrina, D; Schael, S; Schellenberg, M; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmelzer, T; Schmidt, B; Schneider, O; Schopper, A; Schubert, K; Schubiger, M; Schune, M-H; Schwemmer, R; Sciascia, B; Sciubba, A; Semennikov, A; Sergi, A; Serra, N; Serrano, J; Sestini, L; Seyfert, P; Shapkin, M; Shapoval, I; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, V; Siddi, B G; Silva Coutinho, R; Silva de Oliveira, L; Simi, G; Simone, S; Sirendi, M; Skidmore, N; Skwarnicki, T; Smith, E; Smith, I T; Smith, J; Smith, M; Snoek, H; Soares Lavra, L; Sokoloff, M D; Soler, F J P; Souza De Paula, B; Spaan, B; Spradlin, P; Sridharan, S; Stagni, F; Stahl, M; Stahl, S; Stefko, P; Stefkova, S; Steinkamp, O; Stemmle, S; Stenyakin, O; Stevens, H; Stevenson, S; Stoica, S; Stone, S; Storaci, B; Stracka, S; Straticiuc, M; Straumann, U; Sun, L; Sutcliffe, W; Swientek, K; Syropoulos, V; Szczekowski, M; Szumlak, T; T'Jampens, S; Tayduganov, A; Tekampe, T; Tellarini, G; Teubert, F; Thomas, E; van Tilburg, J; Tilley, M J; Tisserand, V; Tobin, M; Tolk, S; Tomassetti, L; Tonelli, D; Topp-Joergensen, S; Toriello, F; Tournefier, E; Tourneur, S; Trabelsi, K; Traill, M; Tran, M T; Tresch, M; Trisovic, A; Tsaregorodtsev, A; Tsopelas, P; Tully, A; Tuning, N; Ukleja, A; Ustyuzhanin, A; Uwer, U; Vacca, C; Vagnoni, V; Valassi, A; Valat, S; Valenti, G; Vazquez Gomez, R; Vazquez Regueiro, P; Vecchi, S; van Veghel, M; Velthuis, J J; Veltri, M; Veneziano, G; Venkateswaran, A; Vernet, M; Vesterinen, M; Viana Barbosa, J V; Viaud, B; Vieira, D; Vieites Diaz, M; Viemann, H; Vilasis-Cardona, X; Vitti, M; Volkov, V; Vollhardt, A; Voneki, B; Vorobyev, A; Vorobyev, V; Voß, C; de Vries, J A; Vázquez Sierra, C; Waldi, R; Wallace, C; Wallace, R; Walsh, J; Wang, J; Ward, D R; Wark, H M; Watson, N K; Websdale, D; Weiden, A; Whitehead, M; Wicht, J; Wilkinson, G; Wilkinson, M; Williams, M; Williams, M P; Williams, M; Williams, T; Wilson, F F; Wimberley, J; Wishahi, J; Wislicki, W; Witek, M; Wormser, G; Wotton, S A; Wraight, K; Wyllie, K; Xie, Y; Xing, Z; Xu, Z; Yang, Z; Yao, Y; Yin, H; Yu, J; Yuan, X; Yushchenko, O; Zarebski, K A; Zavertyaev, M; Zhang, L; Zhang, Y; Zhang, Y; Zhelezov, A; Zheng, Y; Zhu, X; Zhukov, V; Zucchelli, S

2017-01-01

A measurement of the phase difference between the short- and long-distance contributions to the [Formula: see text] decay is performed by analysing the dimuon mass distribution. The analysis is based on pp collision data corresponding to an integrated luminosity of 3[Formula: see text] collected by the LHCb experiment in 2011 and 2012. The long-distance contribution to the [Formula: see text] decay is modelled as a sum of relativistic Breit-Wigner amplitudes representing different vector meson resonances decaying to muon pairs, each with their own magnitude and phase. The measured phases of the [Formula: see text] and [Formula: see text] resonances are such that the interference with the short-distance component in dimuon mass regions far from their pole masses is small. In addition, constraints are placed on the Wilson coefficients, [Formula: see text] and [Formula: see text], and the branching fraction of the short-distance component is measured.

About SEEs in the HV Distributor System of the TileCal

CERN Document Server

Chadelas, R; Lambert, D

2002-01-01

SEE tests performed in october 2001 (27-28) on the HV distributor system of the Tile calorimeter gave us estimated numbers concerning soft and latch-up events. Even if the rates seen will not prevent the device from running, it is important to try to reduce them and to predict how the system will react in particular to latch-ups. This note describes the efforts developped to reduce SEE rates and to secure the behaviour of the system with respect to latch-ups.

Bug bites and stings: When to see a dermatologist

Medline Plus

Full Text Available ... facts about your skin, hair, and nails Skin dictionary Camp Discovery Good Skin Knowledge lesson plans and activities Video library Find a dermatologist Why see a board-certified dermatologist? Home ...

Enhancing Indigenous Health Promotion Research Through Two-Eyed Seeing: A Hermeneutic Relational Process.

Science.gov (United States)

Hovey, Richard B; Delormier, Treena; McComber, Alex M; Lévesque, Lucie; Martin, Debbie

2017-07-01

The intention of this article is to demonstrate how Indigenous and allied health promotion researchers learned to work together through a process of Two-Eyed Seeing. This process was first introduced as a philosophical hermeneutic research project on diabetes prevention within an Indigenous community in Quebec Canada. We, as a research team, became aware that hermeneutics and the principles of Haudenosaunee decision making were characteristic of Two-Eyed Seeing. This article describes our experiences while working with each other. Our learning from these interactions emphasized the relational aspects needed to ensure that we became a highly functional research team while working together and becoming Two-Eyed Seeing partners.

Hanford site past practice investigation strategy: Lessons learned

International Nuclear Information System (INIS)

Thompson, K. Michael

1992-01-01

The U. S. Department of Energy (DOE), U. S. Environmental Protection Agency (EPA), and the Washington State Department of Ecology (Ecology) have negotiated a strategy for performing Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) and Resource Conservation and Recovery Act (RCRA) Past Practice investigations in a more streamlined manner with a bias-for-action. This strategy provides new concepts for 1) accelerating decision-making by maximizing the use of existing data consistent with data quality objectives and 2) undertaking expedited response actions and/or interim remedial measures as appropriate to either remove threats to human health and welfare and the environment or to reduce risk by reducing toxicity, mobility or volume of contaminants. Since the goal of the program is cleanup, much more emphasis will be placed on initiating and completing waste site cleanups through interim measures. While investigations and studies are important in meeting long-range goals, there is now agreement by the parties that an appropriate and significant portion of the near-term funding resources can and should be dedicated to remedial work, where there is sufficient information from which to plan and implement interim remedial measures. The initial stages of Hanford clean-up will optimize the use of interim cleanup actions when justified and practicable. Existing data will be evaluated as the initial basis for decision-making. If the data are found to be insufficient, additional essential data will be collected to support the IRM in a limited field investigation (LFI). Only data needed to formulate a conceptual model (source to pathway to receptor) and qualitative risk assessment would be obtained. The data quality objectives of the LFI will be established based on the use of the data in deciding on IRMs. The data might not need to be of the same quality needed to support final RODs, since the IRM itself would yield valuable information for

Methodological possibilities for the solution of new tasks for “Thermophysics of Power Units” Department of SPbPU

Science.gov (United States)

Sapozhnikov, S. Z.; Mityakov, V. Yu; Mityakov, A. V.; Gusakov, A. A.

2017-11-01

“Thermophysics of Power Units” Department is based on pre-existed “Thermodynamics and Heat Transfer” and “Reactors and Boilers” Departments. The main goal of the new department (in addition to training students in basic courses of Thermodynamics, Heat and Mass Transfer, Fluid Mechanics, Metrology and Thermal Measurement) has become a new master’s profile “Thermal Engineering, Energy Audit and Energy Service”. It required radical restructuring of the whole educational process, and in the first place - its material resources and equipment. Over the last two years “Heat and Mass Transfer” lab and “Wind tunnel” lab are upgraded, and “Metrology and Thermophysical Measurement” lab is newly created. Tutorials of new generation are changing significantly the structure of our main courses. The members of our scientific group (2 - 6 year students) actively engaged in the work process. Now we hope to see the best of them among our future postgraduates.

An Extended Design of the "Grid-Enabled SEE++ System" Based on Globus Toolkit 4 and gLite Conference

CERN Document Server

Schreiner, W.; Buchberger, M.; Kaltofen, T.

2006-01-01

"Grid-Enabled SEE++" based on the SEE++ software system for the biomechanical 3D simulation of the human eye and its muscles. SEE++ simulates the common eye muscle surgery techniques in a graphic interactive way that is familiar to an experienced surgeon. The goal of "Grid-Enabled SEE++" is to adapt and to extend SEE++ in several steps and to develop an efficient grid-based tool for "Evidence Based Medicine", which supports the surgeons in choosing optimal surgery techniques for the treatments of different syndromes of strabismus. In our previous work, we combined the SEE++ software with the Globus (pre-Web Service) middleware and developed a parallel version of the simulation of the "Hess-Lancaster test" (typical medical examination). By this, we demonstrated how a noticeable speedup can be achieved in SEE++ by the exploitation of the computational power of the Grid. Furthermore, we reported the prototype implementation of a medical database component for "Grid-Enabled SEE++". Finally, we designed a so calle...

Emergency Department Presentations following Tropical Cyclone Yasi.

Directory of Open Access Journals (Sweden)

Peter Aitken

Full Text Available Emergency departments see an increase in cases during cyclones. The aim of this study is to describe patient presentations to the Emergency Department (ED of a tertiary level hospital (Townsville following a tropical cyclone (Yasi. Specific areas of focus include changes in: patient demographics (age and gender, triage categories, and classification of diseases.Data were extracted from the Townsville Hospitals ED information system (EDIS for three periods in 2009, 2010 and 2011 to coincide with formation of Cyclone Yasi (31 January 2011 to six days after Yasi crossed the coast line (8 February 2012. The analysis explored the changes in ICD10-AM 4-character classification and presented at the Chapter level.There was a marked increase in the number of patients attending the ED during Yasi, particularly those aged over 65 years with a maximum daily attendance of 372 patients on 4 Feb 2011. The most marked increases were in: Triage categories--4 and 5; and ICD categories--diseases of the skin and subcutaneous tissue (L00-L99, and factors influencing health care status (Z00-Z99. The most common diagnostic presentation across all years was injury (S00-T98.There was an increase in presentations to the ED of TTH, which peaked in the first 24-48 hours following the cyclone and returned to normal over a five-day period. The changes in presentations were mostly an amplification of normal attendance patterns with some altered areas of activity. Injury patterns are similar to overseas experience.

SeeDB: Efficient Data-Driven Visualization Recommendations to Support Visual Analytics.

Science.gov (United States)

Vartak, Manasi; Rahman, Sajjadur; Madden, Samuel; Parameswaran, Aditya; Polyzotis, Neoklis

2015-09-01

Data analysts often build visualizations as the first step in their analytical workflow. However, when working with high-dimensional datasets, identifying visualizations that show relevant or desired trends in data can be laborious. We propose SeeDB, a visualization recommendation engine to facilitate fast visual analysis: given a subset of data to be studied, SeeDB intelligently explores the space of visualizations, evaluates promising visualizations for trends, and recommends those it deems most "useful" or "interesting". The two major obstacles in recommending interesting visualizations are (a) scale : evaluating a large number of candidate visualizations while responding within interactive time scales, and (b) utility : identifying an appropriate metric for assessing interestingness of visualizations. For the former, SeeDB introduces pruning optimizations to quickly identify high-utility visualizations and sharing optimizations to maximize sharing of computation across visualizations. For the latter, as a first step, we adopt a deviation-based metric for visualization utility, while indicating how we may be able to generalize it to other factors influencing utility. We implement SeeDB as a middleware layer that can run on top of any DBMS. Our experiments show that our framework can identify interesting visualizations with high accuracy. Our optimizations lead to multiple orders of magnitude speedup on relational row and column stores and provide recommendations at interactive time scales. Finally, we demonstrate via a user study the effectiveness of our deviation-based utility metric and the value of recommendations in supporting visual analytics.

Infection-related and -unrelated malignancies, HIV and the aging population.

Science.gov (United States)

Shepherd, L; Borges, Áh; Ledergerber, B; Domingo, P; Castagna, A; Rockstroh, J; Knysz, B; Tomazic, J; Karpov, I; Kirk, O; Lundgren, J; Mocroft, A

2016-09-01

HIV-positive people have increased risk of infection-related malignancies (IRMs) and infection-unrelated malignancies (IURMs). The aim of the study was to determine the impact of aging on future IRM and IURM incidence. People enrolled in EuroSIDA and followed from the latest of the first visit or 1 January 2001 until the last visit or death were included in the study. Poisson regression was used to investigate the impact of aging on the incidence of IRMs and IURMs, adjusting for demographic, clinical and laboratory confounders. Linear exponential smoothing models forecasted future incidence. A total of 15 648 people contributed 95 033 person-years of follow-up, of whom 610 developed 643 malignancies [IRMs: 388 (60%); IURMs: 255 (40%)]. After adjustment, a higher IRM incidence was associated with a lower CD4 count [adjusted incidence rate ratio (aIRR) CD4 count IRMs. The incidences of both IURMs and IRMs increased with older age. It was projected that the incidence of IRMs would decrease by 29% over a 5-year period from 3.1 (95% CI 1.5-5.9) per 1000 person-years in 2011, whereas the IURM incidence would increase by 44% from 4.1 (95% CI 2.2-7.2) per 1000 person-years over the same period. Demographic and HIV-related risk factors for IURMs (aging and smoking) and IRMs (immunodeficiency and ongoing viral replication) differ markedly and the contribution from IURMs relative to IRMs will continue to increase as a result of aging of the HIV-infected population, high smoking and lung cancer prevalence and a low prevalence of untreated HIV infection. These findings suggest the need for targeted preventive measures and evaluation of the cost-benefit of screening for IURMs in HIV-infected populations. © 2016 British HIV Association.

Frequency and Nature of Infectious Risk Moments During Acute Care Based on the INFORM Structured Classification Taxonomy.

Science.gov (United States)

Clack, Lauren; Passerini, Simone; Wolfensberger, Aline; Sax, Hugo; Manser, Tanja

2018-03-01

OBJECTIVE In this study, we sought to establish a comprehensive inventory of infectious risk moments (IRMs), defined as seemingly innocuous yet frequently occurring care manipulations potentially resulting in transfer of pathogens to patients. We also aimed to develop and employ an observational taxonomy to quantify the frequency and nature of IRMs in acute-care settings. DESIGN Prospective observational study and establishment of observational taxonomy. SETTING Intensive care unit, general medical ward, and emergency ward of a university-affiliated hospital. PARTICIPANTS Healthcare workers (HCWs) METHODS Exploratory observations were conducted to identify IRMs, which were coded based on the surfaces involved in the transmission pathway to establish a structured taxonomy. Structured observations were performed using this taxonomy to quantify IRMs in all 3 settings. RESULTS Following 129.17 hours of exploratory observations, identified IRMs involved HCW hands, gloves, care devices, mobile objects, and HCW clothing and accessories. A structured taxonomy called INFORM (INFectiOus Risk Moment) was established to classify each IRM according to the source, vector, and endpoint of potential pathogen transfer. We observed 1,138 IRMs during 53.77 hours of structured observations (31.25 active care hours) for an average foundation of 42.8 IRMs per active care hour overall, and average densities of 34.9, 36.8, and 56.3 IRMs in the intensive care, medical, and emergency wards, respectively. CONCLUSIONS Hands and gloves remain among the most important contributors to the transfer of pathogens within the healthcare setting, but medical devices, mobile objects, invasive devices, and HCW clothing and accessories may also contribute to patient colonization and/or infection. The INFORM observational taxonomy and IRM inventory presented may benefit clinical risk assessment, training and education, and future research. Infect Control Hosp Epidemiol 2018;39:272-279.

Bug bites and stings: When to see a dermatologist

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Bug bites and stings: When to see a dermatologist

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Bug bites and stings: When to see a dermatologist

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Full Text Available ... aging skin care Kids’ zone About skin: Your body's largest organ About hair: Not just on your ... bug bite, such as a rash, fever, or body aches, see your doctor or a board-certified ...

Bug bites and stings: When to see a dermatologist

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Full Text Available ... to remove a tick How to treat a bee sting When to see a dermatologist Burns Frostbite ... following tips: For painful bites , such as a bee sting, take an over-the-counter painkiller, such ...

Bug bites and stings: When to see a dermatologist

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Improved detection of sugar addition to maple syrup using malic acid as internal standard and in 13C isotope ratio mass spectrometry (IRMS).

Science.gov (United States)

Tremblay, Patrice; Paquin, Réal

2007-01-24

Stable carbon isotope ratio mass spectrometry (delta13C IRMS) was used to detect maple syrup adulteration by exogenous sugar addition (beet and cane sugar). Malic acid present in maple syrup is proposed as an isotopic internal standard to improve actual adulteration detection levels. A lead precipitation method has been modified to isolate quantitatively malic acid from maple syrup using preparative reversed-phase liquid chromatography. The stable carbon isotopic ratio of malic acid isolated from this procedure shows an excellent accuracy and repeatability of 0.01 and 0.1 per thousand respectively, confirming that the modified lead precipitation method is an isotopic fractionation-free process. A new approach is proposed to detect adulteration based on the correlation existing between the delta13Cmalic acid and the delta13Csugars-delta13Cmalic acid (r = 0.704). This technique has been tested on a set of 56 authentic maple syrup samples. Additionally, authentic samples were spiked with exogeneous sugars. The mean theoretical detection level was statistically lowered using this technique in comparison with the usual two-standard deviation approach, especially when maple syrup is adulterated with beet sugar : 24 +/- 12% of adulteration detection versus 48 +/- 20% (t-test, p = 7.3 x 10-15). The method was also applied to published data for pineapple juices and honey with the same improvement.

Constraints on the [Formula: see text] form factor from analyticity and unitarity.

Science.gov (United States)

Ananthanarayan, B; Caprini, I; Kubis, B

Motivated by the discrepancies noted recently between the theoretical calculations of the electromagnetic [Formula: see text] form factor and certain experimental data, we investigate this form factor using analyticity and unitarity in a framework known as the method of unitarity bounds. We use a QCD correlator computed on the spacelike axis by operator product expansion and perturbative QCD as input, and exploit unitarity and the positivity of its spectral function, including the two-pion contribution that can be reliably calculated using high-precision data on the pion form factor. From this information, we derive upper and lower bounds on the modulus of the [Formula: see text] form factor in the elastic region. The results provide a significant check on those obtained with standard dispersion relations, confirming the existence of a disagreement with experimental data in the region around [Formula: see text].

Is there a see-saw over an ice-free Arctic Ocean?

Science.gov (United States)

Stendel, Martin; Yang, Shuting; Langen, Peter; Rodehacke, Christian; Mottram, Ruth; Hesselbjerg Christensen, Jens

2017-04-01

The "see-saw" in winter temperatures between western Greenland and the Canadian Arctic on one side and northern Europe on the other has been described by Loewe already in 1937, but actually this behaviour was at least known since the Danish colonization of Greenland in the early 18th century. The see-saw is associated with pressure anomalies not only near the region of interest, but as remote as the Mediterranean and the North Pacific. Recent research has pointed out the role of sea ice in maintaining the see-saw in either its warm or its cold phase over extended periods, which strongly affects European winter temperatures. What would happen to the seesaw if Arctic sea ice were to disappear suddenly? In the framework of the FP7-funded project ice2ice, we try to answer this and related questions. We have conducted a very long global simulation with a global climate model interactively coupled to a Greenland ice sheet component, covering the period 1850-3250 at a horizontal resolution of approximately 125 km. Up to 2005, the forcing is from observed greenhouse gas concentrations, and from 2006 onward it follows the extended RCP8.5 scenario, in which greenhouse gas concentrations continue to increase and eventually level out around 2250. With such a strong forcing, all Arctic sea ice has completely disappeared by roughly the same time, and the surface mass balance of the Greenland Ice Sheet becomes strongly negative. We investigate how the see-saw behaves in such an ice-free world and which implications circulation changes have in the Arctic and over Europe. To further elucidate the role of sea ice distribution on the atmospheric flow and the role of surface fluxes in maintaining the Greenland-European see-saw, we intend at a later time to expand our analysis to include a contrasting simulation with both western Greenland and northern Europe covered by ice during the Last Glacier Maximum.

Efficient Adoption and Assessment of Multiple Process Improvement Reference Models

Directory of Open Access Journals (Sweden)

Simona Jeners

2013-06-01

Full Text Available A variety of reference models such as CMMI, COBIT or ITIL support IT organizations to improve their processes. These process improvement reference models (IRMs cover different domains such as IT development, IT Services or IT Governance but also share some similarities. As there are organizations that address multiple domains and need to coordinate their processes in their improvement we present MoSaIC, an approach to support organizations to efficiently adopt and conform to multiple IRMs. Our solution realizes a semantic integration of IRMs based on common meta-models. The resulting IRM integration model enables organizations to efficiently implement and asses multiple IRMs and to benefit from synergy effects.

Internal Representational Models of Attachment Relationships.

Science.gov (United States)

Crittenden, Patricia M.

This paper outlines several properties of internal representational models (IRMs) and offers terminology that may help to differentiate the models. Properties of IRMs include focus, memory systems, content, cognitive function, "metastructure," quality of attachment, behavioral strategies, and attitude toward attachment. An IRM focuses on…

From LDEF to a national Space Environment and Effects (SEE) program: A natural progression

Science.gov (United States)

Bowles, David E.; Calloway, Robert L.; Funk, Joan G.; Kinard, William H.; Levine, Arlene S.

1995-02-01

As the LDEF program draws to a close, it leaves in place the fundamental building blocks for a Space Environment and Effects (SEE) program. Results from LDEF data analyses and investigations now form a substantial core of knowledge on the long term effects of the space environment on materials, system and structures. In addition, these investigations form the basic structure of a critically-needed SEE archive and database system. An agency-wide effort is required to capture all elements of a SEE program to provide a more comprehensive and focused approach to understanding the space environment, determining the best techniques for both flight and ground-based experimentation, updating the models which predict both the environments and those effects on subsystems and spacecraft, and, finally, ensuring that this multitudinous information is properly maintained, and inserted into spacecraft design programs. Many parts and pieces of a SEE program already exist at various locations to fulfill specific needs. The primary purpose of this program, under the direction of the Office of Advanced Concepts and Technology (OACT) in NASA Headquarters, is to take advantage of these parts; apply synergisms where possible; identify and when possible fill-in gaps; coordinate and advocate a comprehensive SEE program. The SEE program must coordinate and support the efforts of well-established technical communities wherein the bulk of the work will continue to be done. The SEE program will consist of a NASA-led SEE Steering Committee, consisting of government and industry users, with the responsibility for coordination between technology developers and NASA customers; and Technical Working Groups with primary responsibility for program technical content in response to user needs. The Technical Working Groups are as follows: Materials and Processes; Plasma and Fields; Ionizing Radiation; Meteoroids and Orbital Debris; Neutral External Contamination; Thermosphere, Thermal, and Solar

INTEGRAL sees IGR J17544-2619 active again

DEFF Research Database (Denmark)

Chenevez, Jérôme; Kuulkers, Erik; Brandt, Søren

2010-01-01

INTEGRAL Galactic bulge monitoring observations (see, e.g., ATels #438 and #1266) between UT 29 Aug 2010 22:54 and 30 Aug 2010 02:35 revealed X-ray flaring from the Supergiant Fast X-ray Transient (SFXT) IGR J17544-2619. Its last activity was reported about 180 days ago, in March 2010 (ATel #2463...

You are so beautiful... to me: seeing beyond biases and achieving accuracy in romantic relationships.

Science.gov (United States)

Solomon, Brittany C; Vazire, Simine

2014-09-01

Do romantic partners see each other realistically, or do they have overly positive perceptions of each other? Research has shown that realism and positivity co-exist in romantic partners' perceptions (Boyes & Fletcher, 2007). The current study takes a novel approach to explaining this seemingly paradoxical effect when it comes to physical attractiveness--a highly evaluative trait that is especially relevant to romantic relationships. Specifically, we argue that people are aware that others do not see their partners as positively as they do. Using both mean differences and correlational approaches, we test the hypothesis that despite their own biased and idiosyncratic perceptions, people have 2 types of partner-knowledge: insight into how their partners see themselves (i.e., identity accuracy) and insight into how others see their partners (i.e., reputation accuracy). Our results suggest that romantic partners have some awareness of each other's identity and reputation for physical attractiveness, supporting theories that couple members' perceptions are driven by motives to fulfill both esteem- and epistemic-related needs (i.e., to see their partners positively and realistically). 2014 APA, all rights reserved

Multi-layered see-through movie in diminished reality

Science.gov (United States)

Uematsu, Yuko; Hashimoto, Takanori; Inoue, Takuya; Shimizu, Naoki; Saito, Hideo

2012-03-01

This paper presents generating a multi-layered see-through movie for an auto-stereoscopic display. This work is based on Diminished Reality (DR), which is one of the research fields of Augmented Reality (AR). In the usual AR, some virtual objects are added on the real world. On the other hand, DR removes some real objects from the real world. Therefore, the background is visualized instead of the real objects (obstacles) to be removed. We use multiple color cameras and one TOF depth camera. The areas of obstacles are defined by using the depth camera based on the distance of obstacles. The background behind the obstacles is recovered by planarprojection of multiple cameras. Then, the recovered background is overlaid onto the removed obstacles. For visualizing it through the auto-stereoscopic display, the scene is divided into multiple layers such as obstacles and background. The pixels corresponding to the obstacles are not visualized or visualized semi-transparently at the center viewpoints. Therefore, we can see that the obstacles are diminished according to the viewpoints.

[13C] GC-C-IRMS analysis of methylboronic acid derivatives of glucose from liver glycogen after the ingestion of [13C] labeled tracers in rats.

Science.gov (United States)

Luengo, Catherine; Azzout-Marniche, Dalila; Fromentin, Claire; Piedcoq, Julien; Lemosquet, Sophie; Tomé, Daniel; Gaudichon, Claire

2009-11-01

We developed a complete method to measure low [(13)C] enrichments in glycogen. Fourteen rats were fed a control diet. Six of them also ingested either [U-(13)C] glucose (n=2) or a mixture of 20 [U-(13)C] amino acids (n=4). Hepatic glycogen was extracted, digested to glucose and purified on anion-cation exchange resins. After the optimization of methylboronic acid derivatization using GC-MS, [(13)C] enrichment of extracted glucose was measured by GC-C-IRMS. The accuracy was addressed by measuring the enrichment excess of a calibration curve, which observed values were in good agreement with the expected values (R=0.9979). Corrected delta values were -15.6+/-1.6 delta(13)C (per thousand) for control rats (n=8) and increased to -5 to 8 delta(13)C (per thousand) per thousand and 12-14 delta(13)C (per thousand) per thousand after the ingestion of [U-(13)C] amino acids or [U-(13)C] glucose as oral tracers, respectively. The method enabled the determination of dietary substrate transfer into glycogen. The sequestration of dietary glucose in liver glycogen 4 h after the meal was 35% of the ingested dose whereas the transfer of carbon skeletons from amino acids was only 0.25 to 1%.

Seeing Clearly (A Cup of Health with CDC)

Centers for Disease Control (CDC) Podcasts

2014-05-08

If you’re not seeing the world as clearly as you used to, you might be among the millions of people suffering from vision impairment. In this podcast, Dr. John Crews discusses ways to take care of your eyes.  Created: 5/8/2014 by MMWR.   Date Released: 5/8/2014.

Suur kera väikese sees / Kalju Kruusa

Index Scriptorium Estoniae

Kruusa, Kalju, pseud., 1973-

2010-01-01

Tutvustus: Hullunud pilv / Ikkyū Sōjun ; klassikalisest hiina keelest tõlkinud ja kommenteerinud Rein Raud. Tallinn : TLU Press, 2010 ; Lind tulemäe kohal : valik XX sajandi teise poole türgi luulet / tõlkinud Andres Ehin ja Ly Seppel. Tallinn : Kultuurileht, 2010 ; Narain, Kunwar. See ainuke maailm : valitud luuletused. Lelle : Allikaääre, 2010

DESIGN AND TEST OF AN INSTRUMENT FOR MEASURING MICROTHERMAL SEEING ON THE MAGDALENA RIDGE

International Nuclear Information System (INIS)

Jorgensen, A. M.; Klinglesmith, D. A.; Speights, J.; Clements, A.; Patel, J.

2009-01-01

We have constructed and operated an automated instrument for measuring ground-level microthermal seeing at the Magdalena Ridge Observatory (MRO). The MRO is located at an altitude of 10500' in the Cibola National Forest in New Mexico, USA. It is the planned site for the MRO Optical Interferometer (MROI) planned for up to 10 collecting elements, each with a diameter of 1.4 m, and baselines eventually up to approximately 400 m. As part of the preparation for construction we deployed a system to characterize the ground-level seeing across the observatory site. The instrument is built largely of off-the-shelf components, with only the sensor head and power supply requiring electronic board assembly. Even in those cases the board architecture is very simple. The first proof-of-concept system was deployed for several weeks in the autumn of 2004, and has since undergone several iterations. The latest configuration operates entirely off batteries, incorporates wireless data acquisition, and is thus able to operate in an area with no shelter, power, or communications. In this paper we present the design of the instrument, and show initial data. The microthermal tower has four sensor pairs at heights from 0.8 to 4.41 m, significantly lower than other microthermal experiments, because of the need to characterize the seeing near the ground. We find significant variation in the contribution of this range of heights to the seeing, contributing up to 0.''3 of the seeing at some times and only 0.''02 at other times. The individual sensor power spectra have a slope in the range of 1.4--1.5, which is lower than the 1.67 slope predicted by Kolmogorov turbulence theory. We measure the well known effect of improved seeing immediately around sunset. While we find significant variation in the microthermal seeing, we did not find a pattern of corresponding variations in weather conditions, suggesting that a complicated set of factors control microthermal turbulence.

Design and Test of an Instrument for Measuring Microthermal Seeing on the Magdalena Ridge

Science.gov (United States)

Jorgensen, A. M.; Klinglesmith, D. A., III; Speights, J.; Clements, A.; Patel, J.

2009-05-01

We have constructed and operated an automated instrument for measuring ground-level microthermal seeing at the Magdalena Ridge Observatory (MRO). The MRO is located at an altitude of 10500' in the Cibola National Forest in New Mexico, USA. It is the planned site for the MRO Optical Interferometer (MROI) planned for up to 10 collecting elements, each with a diameter of 1.4 m, and baselines eventually up to approximately 400 m. As part of the preparation for construction we deployed a system to characterize the ground-level seeing across the observatory site. The instrument is built largely of off-the-shelf components, with only the sensor head and power supply requiring electronic board assembly. Even in those cases the board architecture is very simple. The first proof-of-concept system was deployed for several weeks in the autumn of 2004, and has since undergone several iterations. The latest configuration operates entirely off batteries, incorporates wireless data acquisition, and is thus able to operate in an area with no shelter, power, or communications. In this paper we present the design of the instrument, and show initial data. The microthermal tower has four sensor pairs at heights from 0.8 to 4.41 m, significantly lower than other microthermal experiments, because of the need to characterize the seeing near the ground. We find significant variation in the contribution of this range of heights to the seeing, contributing up to 0farcs3 of the seeing at some times and only 0farcs02 at other times. The individual sensor power spectra have a slope in the range of 1.4--1.5, which is lower than the 1.67 slope predicted by Kolmogorov turbulence theory. We measure the well known effect of improved seeing immediately around sunset. While we find significant variation in the microthermal seeing, we did not find a pattern of corresponding variations in weather conditions, suggesting that a complicated set of factors control microthermal turbulence.

Bug bites and stings: When to see a dermatologist

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Full Text Available ... Origin Part 3: Function Textbook Study notes Image library 3-D animated image library Board Prep Plus Dialogues in Dermatology Dialogues in ... Good Skin Knowledge lesson plans and activities Video library Find a dermatologist Why see a board-certified ...

Seeing Things: Image and Affect

Directory of Open Access Journals (Sweden)

Maria Angel

2011-04-01

Full Text Available In the age of digital media how might we speak about images of torture, and how might we regard the pain of others?  Using the examples of a short film by Alejandra Canales which recounts the experience of torture, and the Abu Ghraib photographs, this article seeks to repose the question of the function of the image and its relationship to epistemology. How do we know what we see? And how might we rethink the orthodox function of the image in the age of digital technology? In attempting to answer these questions, I argue that the production of virtual experience is a capacity of the human body, and that image making, like all genres of communication, is a practice in virtual community.

Comparison of three mouse strains by radiosensitivity of hemato-immune system

International Nuclear Information System (INIS)

Li, Deguan; Wu, Hongying; Wang, Yong; Zhang, Junling; Wang, Yueying; Lu, Lu; Meng, Aimin

2008-01-01

IRM-2, developed in our Lab, is an inbred strain mouse created by cross of a ICR/JCL female and 615 male mouse. Compared to the parent strains, the IRM-2 mouse exhibit increased resistance to radiation. We examine the damage of hemato-immune system induced by radiation in IRM-2, ICR and 615 mice in order to elucidate the radiation resistant mechanism of IRM-2 mouse. The hemato-immune function and radiosensitivities of three mouse strains (IRM-2, ICR/JCL, 615) have been compared using the following parameters: the white blood cells (WBC) in peripheral blood (PB), the bone marrow nucleated cells (BMC) per femur. Percent of phagocytosis of peritoneal macrophage (PM) was checked by chicken red blood cells. Lymphocyte phenotype in PB were analyzed by flow cytometry. Damage induced by radiation were analysed in the bone marrows cells, splenocytes and thymocyte exposed to irradiation in vitro by cell viability assay (ATP Bioluminescence assay) and apoptosis assay (Annexin V/PI). The WBC and BMC of IRM-2 mice were significantly higher than those in ICR mice and 615 mice, respectively (P<0.01). The ratio of CD4/CD8 in PB of IRM-2 mouse was lower than those in ICR and 615, P<0.01. Cell viability showed difference after 18 hs incubation post radiation in three mouse strains. The results of our primary study suggest that the hemato-immune function in IRM-2 mouse is different to its parent strains. The IRM-2 mouse provides an animal model to conducted further investigation to explore the role of hemato-immune system in radiation resistance. (author)

Large and almost maximal neutrino mixing within the type II see-saw mechanism

International Nuclear Information System (INIS)

Lindner, Manfred; Rodejohann, Werner

2007-01-01

Within the type II see-saw mechanism the light neutrino mass matrix is given by a sum of a direct (or triplet) mass term and the conventional (type I) see-saw term. Both versions of the see-saw mechanism explain naturally small neutrino masses, but the type II scenario offers interesting additional possibilities to explain large or almost maximal or vanishing mixings which are discussed in this paper. We first introduce 'type II enhancement' of neutrino mixing, where moderate cancellations between the two terms can lead to large neutrino mixing even if all individual mass matrices and terms generate small mixing. However, nearly maximal or vanishing mixings are not naturally explained in this way, unless there is a certain initial structure (symmetry) which enforces certain elements of the matrices to be identical or related in a special way. We therefore assume that the leading structure of the neutrino mass matrix is the triplet term and corresponds to zero U e3 and maximal θ 23 . Small but necessary corrections are generated by the conventional see-saw term. Then we assume that one of the two terms corresponds to an extreme mixing scenario, such as bimaximal or tri-bimaximal mixing. Deviations from this scheme are introduced by the second term. One can mimic Quark-Lepton Complementarity in this way. Finally, we note that the neutrino mass matrix for tri-bimaximal mixing can be-depending on the mass hierarchy-written as a sum of two terms with simple structure. Their origin could be the two terms of type II see-saw

Fiscal year 2013 energy department budget: Proposed investments in clean energy research

Science.gov (United States)

Balcerak, Ernie

2012-03-01

Energy and environmental research programs generally fared well in President Barack Obama's proposed budget for the Department of Energy (DOE) for fiscal year (FY) 2013. In his State of the Union address, Obama called for the United States to pursue an "all of the above" energy strategy that includes fossil fuels, as well as a variety of renewable sources of energy. The DOE budget request supports that strategy, Energy Secretary Steven Chu said in a 13 February press briefing announcing the budget proposal. The proposed budget gives DOE 27.2 billion overall, a 3.2% increase from the FY 2012 enacted budget (see Table 1). This budget "reflects some tough choices," Chu said. The proposed budget would cut 4 billion in subsidies for oil and gas companies; many Republican members of Congress have already indicated that they oppose such cuts, suggesting that congressional approval of this budget may run into stumbling blocks. The budget would also cut funding for research and development projects that are already attracting private-sector investment or that are not working, and would reduce some of the department's operational costs.

Graduate student driven efforts to increase diversity of department lecture series

Science.gov (United States)

Bryant, R.; Keisling, B. A.

2017-12-01

It is well documented that women and people of color (and especially women of color) remain underrepresented in the geoscience community. As graduate students we noticed this underrepresentation in our department lecture series. Since 2013, 40% of the invited speakers were women and 5% URM, with the majority of the URM scientists coming to campus for an annual special lecture that highlights the work of black geoscientists. Our goals for the 2017-18 lecture series are the following: 1) to increase the percentage of women speakers from 40% to 50% or higher, 2) to increase the participation of URM scientists from one per year to at least one per semester, 3) to expand the established annual special lecture highlighting contributions from black geoscientists from one lecture to four, and 4) to motivate a department-wide conversation surrounding the issues and significance of inclusion and equity in our departmental geoscience community and beyond. Our focus on gender, race, and ethnicity in diversifying the lecture series unfortunately falls short of capturing the full range of perspectives from groups that are underrepresented as defined by the NSF. We see our work as a first step and hope to encourage more conversations about broader diversity. To accomplish our goals, we will seek advice and counsel from scholars in fields like Sociology and Education, as well as pursue external funding to bolster the budget allocated by our department. As graduate students, it is important for us to envision facets of our peers and ourselves reflected in the perspectives, experiences and narratives of prominent speakers brought to campus. We find it therefore important that our department lecture series, a highly visible venue, be more inclusive and representative. Our efforts show that seeking external support and setting achievable goals can lead to better representation of underrepresented groups in such spaces.

O cemitério como espaço devocional: um estudo sobre a devoção a Irmã Benigna (The cemetery as devotional space: a study about the devotion to sister Benigna

Directory of Open Access Journals (Sweden)

Ilza Mara Lima

2013-03-01

Full Text Available Este artigo pretende analisar os cemitérios como espaço de múltiplas devoções, dentre elas as devoções marginais: as diversas formas com as quais as pessoas cultuam seus mortos, através de seus túmulos. As devoções que são manifestadas perante esses túmulos dentro dos cemitérios demonstram esta prática de fé, que se denomina de devoção marginal. Pessoas comuns que após a morte, ganham a veneração de fieis que lhe pedem a interseção junto ao sagrado, são cultuadas como milagreiras.  Após o pedido realizado, o devoto passa há ornamentar o tumulo do Milagreiro, com Flores, Velas, Ex votos em forma de agradecimento. O túmulo então se torna objeto de veneração e peregrinação. O artigo examina como esta devoção no cemitério do Bonfim, em Belo Horizonte, mais especificamente no túmulo da milagreira Irmã Benigna, auxilia os devotos nos momentos de suas angústias e aflições. Analisa-se como essa devoção se perpetua à margem da crença oficial. Palavras-chave: Morte. Enterramento. Túmulo. Devoção. Irmã Benigna.   Abstract This article analyzes the cemeteries as a place of many devotions, devotions among them marginal. the various ways in which people worship their dead through their graves. The devotions that are manifested before these graves within the cemeteries demonstrate the practice of faith is called the marginal devotion. Ordinary people who are worshiped as a miracle worker. The article examines how this devotion in the cemetery of Bonfim in Belo Horizonte City, more specifically in the miraculous Num Benigna’s Tomb helps the devotees by the time their distress happene. It looks at how devotion is perpetuated the margin of the official belief. Keywords: Death. Burial. Grave. Devotion. Nun Benigna’s. 

Bug bites and stings: When to see a dermatologist

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Bug bites and stings: When to see a dermatologist

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Full Text Available ... Private payer Medicare physician payment MACRA implementation Alternative payment models Fee schedule State policy State policy and action ... a dermatologist Why see a board-certified dermatologist? Home Public and patients Skin, hair, and nail care Injured skin Bug bites and stings "); (function () { var ...

SEE: structured representation of scientific evidence in the biomedical domain using Semantic Web techniques.

Science.gov (United States)

Bölling, Christian; Weidlich, Michael; Holzhütter, Hermann-Georg

2014-01-01

Accounts of evidence are vital to evaluate and reproduce scientific findings and integrate data on an informed basis. Currently, such accounts are often inadequate, unstandardized and inaccessible for computational knowledge engineering even though computational technologies, among them those of the semantic web, are ever more employed to represent, disseminate and integrate biomedical data and knowledge. We present SEE (Semantic EvidencE), an RDF/OWL based approach for detailed representation of evidence in terms of the argumentative structure of the supporting background for claims even in complex settings. We derive design principles and identify minimal components for the representation of evidence. We specify the Reasoning and Discourse Ontology (RDO), an OWL representation of the model of scientific claims, their subjects, their provenance and their argumentative relations underlying the SEE approach. We demonstrate the application of SEE and illustrate its design patterns in a case study by providing an expressive account of the evidence for certain claims regarding the isolation of the enzyme glutamine synthetase. SEE is suited to provide coherent and computationally accessible representations of evidence-related information such as the materials, methods, assumptions, reasoning and information sources used to establish a scientific finding by adopting a consistently claim-based perspective on scientific results and their evidence. SEE allows for extensible evidence representations, in which the level of detail can be adjusted and which can be extended as needed. It supports representation of arbitrary many consecutive layers of interpretation and attribution and different evaluations of the same data. SEE and its underlying model could be a valuable component in a variety of use cases that require careful representation or examination of evidence for data presented on the semantic web or in other formats.

Your Aging Eyes: How You See as Time Goes By

Science.gov (United States)

... Subscribe Special Issue: Seniors Print this issue Your Aging Eyes How You See as Time Goes By ... Building Social Bonds Coping with Caregiving Osteoporosis in Aging Wise Choices Protect Your Vision Have a comprehensive ...

Do we see what we should see? Describing non-covalent interactions in protein structures including precision

Directory of Open Access Journals (Sweden)

Manickam Gurusaran

2014-01-01

Full Text Available The power of X-ray crystal structure analysis as a technique is to `see where the atoms are'. The results are extensively used by a wide variety of research communities. However, this `seeing where the atoms are' can give a false sense of security unless the precision of the placement of the atoms has been taken into account. Indeed, the presentation of bond distances and angles to a false precision (i.e. to too many decimal places is commonplace. This article has three themes. Firstly, a basis for a proper representation of protein crystal structure results is detailed and demonstrated with respect to analyses of Protein Data Bank entries. The basis for establishing the precision of placement of each atom in a protein crystal structure is non-trivial. Secondly, a knowledge base harnessing such a descriptor of precision is presented. It is applied here to the case of salt bridges, i.e. ion pairs, in protein structures; this is the most fundamental place to start with such structure-precision representations since salt bridges are one of the tenets of protein structure stability. Ion pairs also play a central role in protein oligomerization, molecular recognition of ligands and substrates, allosteric regulation, domain motion and α-helix capping. A new knowledge base, SBPS (Salt Bridges in Protein Structures, takes these structural precisions into account and is the first of its kind. The third theme of the article is to indicate natural extensions of the need for such a description of precision, such as those involving metalloproteins and the determination of the protonation states of ionizable amino acids. Overall, it is also noted that this work and these examples are also relevant to protein three-dimensional structure molecular graphics software.

Method of reactor fueling

International Nuclear Information System (INIS)

Saito, Toshiro.

1983-01-01

Purpose: To decrease the cost and shorten the working time by saving fueling neutron detectors and their components. Method: Incore drive tubes for the neutron source range monitor (SRM) and intermediate range monitor (IRM) are disposed respectively within in a reactor core and a SRM detector assembly is inserted to the IRM incore drive tube which is most nearest to the neutron source upon reactor fueling. The reactor core reactivity is monitored by the SRM detector assembly. The SRM detector asesembly inserted into the IRM drive tube is extracted at the time of charging fuels up to the frame connecting the SRM and, thereafter, IRM detection assembly is inserted into the IRM drive tube and the SRM detector assembly is inserted into the SRM drive tube respectively for monitoring the reactor core. (Sekiya, K.)

Monitoring of ionospheric turbulence spatial features by SEE diagnostic tools

Science.gov (United States)

Sergeev, E. N.; Boiko, G. N.; Shvarts, M. M.; Grach, S. M.; Kotov, P. V.

Spatial features of HF pumped ionospheric F-region are investigated experimentally at the SURA facility by means of the stimulated electromagnetic emission (SEE). SEE, recall, appears as a result of conversion (or scattering) of HF pump-driven plasma waves off the geomagnetic field aligned electron density irregularities (striations). A specially designed pumping scheme was elaborated to study an influence of the perturbations of the electron density and temperature, created by powerful pump wave at frequency f_h and occupying quite extended altitude range (range-I), on spectral and temporal evolution of the diagnostic SEE (DSEE) generated by a weak continuous or pulse diagnostic wave at a frequency f_d in an altitude range-II, spatially shifted from the centre of the range-I. New two-channel digital receiver allowed to analyze the SEE from both ranges (around both frequencies f_h and f_d) simultaneously. A combination of the SEE diagnostics and computer simulations allowed to study:% (a) dependences of striation spectrum and dynamics on the frequency shift |f_h-f_d| (which can be easily translated to the altitude displacement), powers of the pump and diagnostic waves, offsets of the frequencies f_h and f_d from electron gyroharmonics, and on the daily conditions. It is found that a slow (time scale of 1--10 s) dynamics of DSEE, namely, characteristics of its slow overshoot and undershoot effects are determined by the spectral shape and intensity of the striations at, respectively, the development and relaxation stages. It is shown that the striation spectrum flattens in meter scale range for f_h between 3th and 4th gyroharmonics in comparison with larger f_h, in the centre of the range-I in comparison with its periphery, that the range-I extension increases with its altitude and with a transition from day to night conditions;% (b) an influence of the powerful pumping on ``diagnostic'' HF plasma wave evolution by measurements of growth and decay times of the DSEE

Weak convergence to isotropic complex [Formula: see text] random measure.

Science.gov (United States)

Wang, Jun; Li, Yunmeng; Sang, Liheng

2017-01-01

In this paper, we prove that an isotropic complex symmetric α -stable random measure ([Formula: see text]) can be approximated by a complex process constructed by integrals based on the Poisson process with random intensity.

[See sinine sirjendav kaugus : Bernard Kangro ridade vahel tuhlates] / B. M.

Index Scriptorium Estoniae

Melts, Brita, 1984-

2016-01-01

Tutvustus: See sinine sirjendav kaugus : Bernard Kangro ridade vahel tuhlates : Kangro luulest inspireeritud raamat, joonistused, heliplaat ja film / [koostaja Urmas Bereczki. Tallinn : Lepalind, 2016

Comparative study on hematopoietic damage of mice caused by high-dose of gamma-ray irradiation

International Nuclear Information System (INIS)

Wu Hongying; Wang Yueying; Li Deguan; Wang Xiaochun; Zhang Heng; Lu Lu; Chang Jianhui; Du Liqing; Wang Yan; Men Aimin

2010-01-01

Objective: To study the effect of high-dose of gamma-ray irradiation on hematopoiesis injury and recovery of IRM-2 and C57BL/6 J mouse. Methods: The experiment was designed to study the effects of radiation (4 Gy) on spleen index, CFU-S and DNA damage on the 9 th day of IRM-2 and ICR mice and the effects of radiation (6 Gy) on WBC change and its absolute value on the 45 th days of IRM-2 and C57BL/6 J mice. Results: The IRM-2 mouse spleen index, CFU-S and DNA were higher than ICR mouse on the 9 th days, and there were significant difference in CFU-S and DNA (P<0.01). The IRM-2 mouse WBC, RMC, HGB and HCT were higher than C57BL/6 J mouse on the 45 th days, and there were significant difference (P<0.01). Conclusion: IRM-2 mouse hematopoiesis resumes quicker than C57BL/6 J and ICR do after high-dose of gamma-ray irradiation. (authors)

Good Teachers (the Movie You Will Never See)

Science.gov (United States)

Gillard, Colleen

2012-01-01

It began with a trip to the cinema to see Cameron Diaz in her new comedy, "Bad Teacher." It was a bad choice. Not a great flick, but as a parody of bad employees, in terms of things that can get one fired--drugs, alcohol , cheating, foul language, inappropriate sexual behavior--Diaz slams pedal to the metal. She nips out of airline booze bottles…

Mis see jumal meid on loonud? / Rein Veidemann

Index Scriptorium Estoniae

Veidemann, Rein, 1946-

2017-01-01

Eesti teatriuuenduse 1969 aastal lavastas Evald Hermaküla Paul-Eerik Rummo näidendi "Tuhkatriinumäng", Jaan Tooming August Kitzbergi "Laseb käele suud anda". Jaak Alliku arvustus Jaan Toominga lavastusele ilmus ajakirjas Noorus 1970. aasta märtsinumbris pealkirjaga "Mis see jumal meid on loonud?". Sama küsimuse esitab artikli autor. Elumõttest, elu eesmärgist ja tähendusest

Uso das geotecnologias para a caracterização do parque estadual Dois Irmãos, Recife - PE

Directory of Open Access Journals (Sweden)

Juliana Gomes Aragão

2015-12-01

Full Text Available As Unidades de Conservação vem se estabelecendo como uma estratégia imprescindível para a conservação de fragmentos de florestas e da biodiversidade. Devido a sua importância, ferramentas e pesquisas estão sendo cada vez mais desenvolvidas para permitir a atualização da paisagem e para o diagnóstico da situação dessas Unidades de Conservação. Aliado a isso, as geotecnologias estão sendo usadas como alternativas nos estudos ambientais, fornecendo meios para uma análise mais precisa e mais próxima do real. Nessa perspectiva, o objetivo do trabalho foi identificar e analisar as características físicas, topográficas e temáticas do Parque Estadual Dois Irmãos, localizado em Recife – PE, a partir da utilização de técnicas do geoprocessamento, aplicando recursos do software do Sistema de Processamento de Informações Georreferenciadas, o SPRING e o QUANTUM GIS e a utilização de imagens SRTM. Para isso foi realizado trabalho de campo para a captação das coordenadas geográficas de alguns itens do Parque, para a montagem do banco de dados e criação do mapa de estruturas físicas. Também foi utilizado as imagens SRTM para a construção do mapa da declividade e do mapa hipsométrico. Após a criação dos mapas identificou-se os tipos de relevo predominantes do Parque. Em relação à declividade 87% do relevo do Parque foi classificado entre Moderadamente Ondulado a Forte Ondulado e a sua altimetria variou de 0 a 105 metros. Diante dos resultados observados, o uso dos SIG’s e de dados SRTM, revelou-se como uma importante ferramenta empregada na identificação e espacialização prévia das unidades de relevo.

See me through my eyes : Adolescent-parent agreement in personality predicts later self-esteem development

NARCIS (Netherlands)

Luan, Z.; Poorthuis, A.M.G.; Hutteman, R.; Asendorpf, Jens B.; Denissen, J.J.A.; van Aken, M.A.G.

2018-01-01

Achieving a clear view of one’s personality is a challenging but crucial developmental task during adolescence, which has enduring influences. This task might be harder if significant others see individuals differently from how the adolescents see themselves. Supporting this, the looking-glass-self

A critical evaluation of the evidence for multiple Late Pleistocene eruptions of Laacher See Volcano

DEFF Research Database (Denmark)

Zernack, Anke Verena; Hoggard, Christian Steven; Sauer, Florian Rudolf

The c. 12,900 BP Plinian eruption of Laacher See Volcano is one of the largest known volcanic events of the Late Pleistocene in the Northern Hemisphere. It buried proximal areas under tens of meters of pyroclastic flow, surge and fallout deposits and deposited a widespread tephra layer across much...... of dispersal of the products from varying eruptive stages and some sites even report two distinct Laacher See Tephra layers that have been interpreted as evidence of a precursor eruption. In order to assess the potential for multiple Late Pleistocene eruptions of Laacher See Volcano, we have compiled...

Seeing you seeing me: Stereotypes and the stigma magnification effect.

Science.gov (United States)

Mikolon, Sven; Kreiner, Glen E; Wieseke, Jan

2016-05-01

[Correction Notice: An Erratum for this article was reported in Vol 101(5) of Journal of Applied Psychology (see record 2016-21000-001). In the article, Table 2 contained a production-related formatting error. Values from column 11 onward were shifted upwards in the table. All versions of this article have been corrected.] Despite an increased interest in the phenomenon of stigma in organizations, we know very little about the interactions between those who are stigmatized and those who stigmatize them. Integrating both the perceptions of the stigmatized worker and the stigmatizing customer into one model, the present study addresses this gap. It examines the role of stereotypes held by customers of stigmatized organizations and metastereotypes held by the stigmatized workers themselves (i.e., their shared beliefs of the stereotypes customers associate with them) in frontline exchanges. To do so, data regarding frontline workers (vendors) of homeless-advocate newspapers from 3 different sources (vendors, customers, trained observers) were gathered. Multilevel path-analytic hypotheses tests reveal (a) how frontline workers' prototypicality for a stigmatized organization renders salient a stigma within frontline interactions and (b) how stereotypes by customers and metastereotypes by frontline workers interact with each other in such contacts. The results support a hypothesized interaction between frontline workers' metastereotypes and customers' stereotypes-what we call the "stigma magnification effect". The study also derives important practical implications by linking stigma to frontline workers' discretionary financial gains. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Integrating Department of Defense Unmanned Aerial Systems into the National Airspace Structure

Science.gov (United States)

2010-06-11

see-and-avoid measures for manned aviation. The FAA definition of see-and-avoid states, “When weather conditions permit, pilots operating IFR ... argument . It either describes what the DoD sees as its current problems to gaining access to the NAS or what the FAA sees as its problems in allowing UAS...

A comprehensive procedure based on gas chromatography–isotope ratio mass spectrometry following high performance liquid chromatography purification for the analysis of underivatized testosterone and its analogues in human urine

International Nuclear Information System (INIS)

Torre, Xavier de la; Colamonici, Cristiana; Curcio, Davide; Molaioni, Francesco; Botrè, Francesco

2012-01-01

Highlights: ► Overall approach for urine samples purification by HPLC for subsequent GC/C/IRMS analysis in doping control. ► Detection of pseudo-endogenous androgenic steroids (i.e. testosterone, androstenedione) misuse in sports. ► Routine analysis of steroids by GC/C/IRMS in sports drug testing. - Abstract: The confirmation by GC/C/IRMS of the exogenous origin of pseudo-endogenous steroids from human urine samples requires extracts of adequate purity. A strategy based on HPLC sample purification prior to the GC/C/IRMS analysis of human urinary endogenous androgens (i.e. testosterone, androsterone and/or androstenediols), is presented. A method without any additional derivatization step is proposed, allowing to simplify the urine pretreatment procedure, leading to extracts free of interferences permitting precise and accurate IRMS analysis, without the need of correcting the measured delta values for the contribution of the derivatizing agent. The HPLC extracts were adequately combined to both reduce the number of GC/C/IRMS runs and to have appropriate endogenous reference compounds (ERC; i.e. pregnanediol, 11-keto-etiocholanolone) on each GC–IRMS run. The purity of the extracts was assessed by their parallel analysis by gas chromatography coupled to mass spectrometry, with GC conditions identical to those of the GC/C/IRMS assay. The method has been validated according to ISO17025 requirements (within assay precision below 0.3 ‰ 13 C delta units and between assay precision below 0.6 ‰ 13 C delta units for most of the compounds investigated) fulfilling the World Anti-Doping Agency requirements.

Teaching technical skills to medical students: Beyond 'see one, do ...

African Journals Online (AJOL)

psychomotor skills based on the 'see one, do one, teach one' ethos. By trial ... approach that begins with building cognitive skills, which can then ... [6] Whatever strategy is used, the objective ... Forward-thinking leadership should be alarmed.

Tequila authenticity assessment by headspace SPME-HRGC-IRMS analysis of 13C/12C and 18O/16O ratios of ethanol.

Science.gov (United States)

Aguilar-Cisneros, Blanca O; López, Mercedes G; Richling, Elke; Heckel, Frank; Schreier, Peter

2002-12-18

By use of headspace SPME sampling and a PLOT column, on-line capillary gas chromatography-isotope ratio mass spectrometry was employed in the combustion (C) and the pyrolysis (P) modes (HRGC-C/P-IRMS) to determine the delta(13)C(VPDB) and delta(18)O(VSMOW) values of ethanol in authentic (n = 14) and commercial tequila samples (n = 15) as well as a number of other spirits (n = 23). Whereas with delta(13)C(VPDB) values ranging from -12.1 to -13.2 per thousand and from -12.5 to -14.8 per thousand similar variations were found for 100% agave and mixed tequilas, respectively, the delta(18)O(VSMOW) data differed slightly within these categories: ranges from +22.1 to +22.8 per thousand and +20.8 to +21.7 per thousand were determined for both the authentic 100% agave and mixed products, respectively. The data recorded for commercial tequilas were less homogeneous; delta(13)C(VPDB) data from -10.6 to -13.9 per thousand and delta(18)O(VSMOW) values from +15.5 to +22.7 per thousand were determined in tequilas of both categories. Owing to overlapping data, attempts to differentiate between white, rested, and aged tequilas within each of the two categories failed. In addition, discrimination of tequila samples from other spirits by means of delta(13)C(VPDB) and delta(18)O(VSMOW) data of ethanol was restricted to the products originating from C(3) as well as C(4)/CAM raw materials.

ANALYSIS OF SEEING-INDUCED POLARIZATION CROSS-TALK AND MODULATION SCHEME PERFORMANCE

International Nuclear Information System (INIS)

Casini, R.; De Wijn, A. G.; Judge, P. G.

2012-01-01

We analyze the generation of polarization cross-talk in Stokes polarimeters by atmospheric seeing, and its effects on the noise statistics of spectropolarimetric measurements for both single-beam and dual-beam instruments. We investigate the time evolution of seeing-induced correlations between different states of one modulation cycle and compare the response to these correlations of two popular polarization modulation schemes in a dual-beam system. Extension of the formalism to encompass an arbitrary number of modulation cycles enables us to compare our results with earlier work. Even though we discuss examples pertinent to solar physics, the general treatment of the subject and its fundamental results might be useful to a wider community.

Florence Nightingale e as irmãs de caridade: revisitando a história Florence Nightingale y las hermanas de caridad: revisitando la historia Florence Nightingale and charity sisters: revisiting the history

Directory of Open Access Journals (Sweden)

Maria Itayra Coelho de Souza Padilha

2005-12-01

Full Text Available O estudo trata de uma reflexão historiográfica acerca dos elos de ligação entre a prática de enfermagem e a influência recebida das ordens/associações religiosas, que marcam o ideário de enfermagem até os dias de hoje, especialmente das Irmãs de Caridade de São Vicente de Paulo. A enfermagem profissional, que só ocorreria no século XIX na Inglaterra, erigida por Florence Nightingale sofreria influência direta dos ensinamentos de amor e fraternidade traduzidos pelo conceito de altruísmo, da valorização do ambiente adequado para o cuidado e a divisão social do trabalho em enfermagem. O estudo mostra também a influência sofrida por Florence Nightingale pelo trabalho exercido pelas Irmãs de Caridade.El estudio trata de una reflexión historiográfica acerca de los eslabones de conexión entre la práctica de enfermería y la influencia recibida de las órdenes/asociaciones religiosas, que marcan el ideario de enfermería hasta los días de hoy, especialmente de las Hermanas de la Caridad de San Vicente de Pablo. La enfermería profesional, que sólo se llevaría a cabo en el siglo XIX en Inglaterra, erigida por Florence Nightingale sufriría influencia directa de las enseñanzas de amor y fraternidad traducidos por el concepto de altruismo, de la valorización del ambiente adecuado para el cuidado y la división social del trabajo en enfermería. El estudio mostra también la influencia sufrida por Florence Nightingale por el trabajo ejercido por las hermanas de la Caridad.This study presents an historical analysis on the links betwen the nursing practice and the influence received from various religious orders/associations along the times, especially from Saint Vincent Paul's charity sisters. The professional nursing which was pioneered by Florence Nightingale in the XIXth century, was directly influenced by the teachings of love and fraternity. In addition, other contributions from the religious orders/associations were the

Is seeing believing? Perceptions of wildfire risk over time

Science.gov (United States)

Patricia A. Champ; Hannah Brenkert-Smith

2016-01-01

Ongoing challenges to understanding how hazard exposure and disaster experiences influence perceived risk lead us to ask: Is seeing believing? We approach risk perception by attending to two components of overall risk perception: perceived probability of an event occurring and perceived consequences if an event occurs. Using a two-period longitudinal data set...

See Me through My Eyes: Adolescent-Parent Agreement in Personality Predicts Later Self-Esteem Development

Science.gov (United States)

Luan, Ziyan; Poorthuis, Astrid M. G.; Hutteman, Roos; Asendorpf, Jens B.; Denissen, Jaap J. A.; van Aken, Marcel A. G.

2018-01-01

Achieving a clear view of one's personality is a challenging but crucial developmental task during adolescence, which has enduring influences. This task might be harder if significant others see individuals differently from how the adolescents see themselves. Supporting this, the looking-glass-self theory suggests that significant others…

Public Health Departments

Data.gov (United States)

Department of Homeland Security — State and Local Public Health Departments in the United States Governmental public health departments are responsible for creating and maintaining conditions that...

Testing a multiple mediation model of Asian American college students' willingness to see a counselor.

Science.gov (United States)

Kim, Paul Youngbin; Park, Irene J K

2009-07-01

Adapting the theory of reasoned action, the present study examined help-seeking beliefs, attitudes, and intent among Asian American college students (N = 110). A multiple mediation model was tested to see if the relation between Asian values and willingness to see a counselor was mediated by attitudes toward seeking professional psychological help and subjective norm. A bootstrapping procedure was used to test the multiple mediation model. Results indicated that subjective norm was the sole significant mediator of the effect of Asian values on willingness to see a counselor. The findings highlight the importance of social influences on help-seeking intent among Asian American college students.

ON IF AND WHETHER COMPLEMENT CLAUSES OF SEE, WONDER, AND KNOW IN CONTEMPORARY SPOKEN ACADEMIC AMERICAN ENGLISH: A CORPUS-BASED STUDY

Directory of Open Access Journals (Sweden)

http://www.rephi.knf.vu.lt/images/24_29/2_6%20Respectus%202013%2024(29%20%20Online%20Issn%20Kazimianec.pdf

2013-10-01

Full Text Available The main goal of this article is to investigate the distribution of two apparently vying finite complementation patterns—if and whether clauses—accompanying three mental verbs (see, wonder, and know in the MICASE corpus of spoken academic American English. The default introspective theoretical assumption that the two investigated complementizers are in a free distribution was not corroborated by the empiricical inquiry. The three verbs do evince linguistic preferences regarding complementation, preferences which depend on a number of factors: the valency pattern of a given verb, co(ntext, sub-genre, and the like. Moreover, the investigation also appears to have demonstrated that, in respect to the complementation of see, wonder, and know, spoken academic English bears a greater resemblance to everyday conversation than to written academic English, thus corroborating the contention that field prevails over mode (to employ Hallidayan parlance. Furthermore, the inquiry into the semantics of the three mental verbs investigated indicates that their meanings are affected by the genre, inasmuch as the verbs investigated tend to depart from their default dictionary definitions by conveying less-prototypical meanings. This finding, in turn, provides a rationale for probing into the pragmatics and functions of the three verbs. It must be stressed that the results should not be generalised due to the relatively small corpus size, which implies that further research is indicated.

Bug bites and stings: When to see a dermatologist

Medline Plus

Full Text Available ... 0; c public SPOT Skin Cancer™ Diseases and treatments Skin, hair, and nail care Skin care Hair care / hair loss Injured skin Blisters Bug bites and stings How to remove a tick How to treat a bee sting When to see a dermatologist Burns Frostbite Splinters Treating sunburn Wound care Nail care ...

A search for [Formula: see text] resonances with the ATLAS detector in 2.05 fb-1 of proton-proton collisions at [Formula: see text].

Science.gov (United States)

Aad, G; Abbott, B; Abdallah, J; Abdel Khalek, S; Abdelalim, A A; Abdinov, O; Abi, B; Abolins, M; AbouZeid, O S; Abramowicz, H; Abreu, H; Acerbi, E; Acharya, B S; Adamczyk, L; Adams, D L; Addy, T N; Adelman, J; Adomeit, S; Adragna, P; Adye, T; Aefsky, S; Aguilar-Saavedra, J A; Agustoni, M; Aharrouche, M; Ahlen, S P; Ahles, F; Ahmad, A; Ahsan, M; Aielli, G; Akdogan, T; Åkesson, T P A; Akimoto, G; Akimov, A V; Alam, M S; Alam, M A; Albert, J; Albrand, S; Aleksa, M; Aleksandrov, I N; Alessandria, F; Alexa, C; Alexander, G; Alexandre, G; Alexopoulos, T; Alhroob, M; Aliev, M; Alimonti, G; Alison, J; Allbrooke, B M M; Allport, P P; Allwood-Spiers, S E; Almond, J; Aloisio, A; Alon, R; Alonso, A; Alvarez Gonzalez, B; Alviggi, M G; Amako, K; Amelung, C; Ammosov, V V; Amorim, A; Amram, N; Anastopoulos, C; Ancu, L S; Andari, N; Andeen, T; Anders, C F; Anders, G; Anderson, K J; Andreazza, A; Andrei, V; Anduaga, X S; Anger, P; Angerami, A; Anghinolfi, F; Anisenkov, A; Anjos, N; Annovi, A; Antonaki, A; 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van Eldik, N; van Gemmeren, P; van Vulpen, I; Vanadia, M; Vandelli, W; Vaniachine, A; Vankov, P; Vannucci, F; Vari, R; Varol, T; Varouchas, D; Vartapetian, A; Varvell, K E; Vassilakopoulos, V I; Vazeille, F; Vazquez Schroeder, T; Vegni, G; Veillet, J J; Veloso, F; Veness, R; Veneziano, S; Ventura, A; Ventura, D; Venturi, M; Venturi, N; Vercesi, V; Verducci, M; Verkerke, W; Vermeulen, J C; Vest, A; Vetterli, M C; Vichou, I; Vickey, T; Vickey Boeriu, O E; Viehhauser, G H A; Viel, S; Villa, M; Villaplana Perez, M; Vilucchi, E; Vincter, M G; Vinek, E; Vinogradov, V B; Virchaux, M; Virzi, J; Vitells, O; Viti, M; Vivarelli, I; Vives Vaque, F; Vlachos, S; Vladoiu, D; Vlasak, M; Vogel, A; Vokac, P; Volpi, G; Volpi, M; Volpini, G; von der Schmitt, H; von Loeben, J; von Radziewski, H; von Toerne, E; Vorobel, V; Vorwerk, V; Vos, M; Voss, R; Voss, T T; Vossebeld, J H; Vranjes, N; Vranjes Milosavljevic, M; Vrba, V; Vreeswijk, M; Vu Anh, T; Vuillermet, R; Vukotic, I; Wagner, W; Wagner, P; Wahlen, H; 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Zhu, J; Zhu, Y; Zhuang, X; Zhuravlov, V; Zieminska, D; Zimin, N I; Zimmermann, R; Zimmermann, S; Zimmermann, S; Ziolkowski, M; Zitoun, R; Živković, L; Zmouchko, V V; Zobernig, G; Zoccoli, A; Zur Nedden, M; Zutshi, V; Zwalinski, L

A search for top quark pair resonances in final states containing at least one electron or muon has been performed with the ATLAS experiment at the CERN Large Hadron Collider. The search uses a data sample corresponding to an integrated luminosity of 2.05 fb -1 , which was recorded in 2011 at a proton-proton centre-of-mass energy of 7 TeV. No evidence for a resonance is found and limits are set on the production cross-section times branching ratio to [Formula: see text] for narrow and wide resonances. For narrow Z ' bosons, the observed 95 % Bayesian credibility level limits range from 9.3 pb to 0.95 pb for masses in the range of m Z ' =500 GeV to m Z ' =1300 GeV. The corresponding excluded mass region for a leptophobic topcolour Z ' boson (Kaluza-Klein gluon excitation in the Randall-Sundrum model) is m Z ' <880 GeV ([Formula: see text]).

Seeing Is Believing? Insights from Young Children in Nature

Science.gov (United States)

White, E. Jayne

2015-01-01

If the eye is a window to the soul, an important question to ask in the early years is "What do children see?" in their encounters with the world. Gaining a better understanding of children's interpretations is central to the pedagogical task of early childhood teachers, yet children are seldom asked to provide their points of view…

A comprehensive procedure based on gas chromatography-isotope ratio mass spectrometry following high performance liquid chromatography purification for the analysis of underivatized testosterone and its analogues in human urine

Energy Technology Data Exchange (ETDEWEB)

Torre, Xavier de la, E-mail: xavier.delatorre@gmail.com [Laboratorio Antidoping, Federazione Medico Sportiva Italiana, Largo Giulio Onesti 1, 00197 Rome (Italy); Colamonici, Cristiana; Curcio, Davide; Molaioni, Francesco [Laboratorio Antidoping, Federazione Medico Sportiva Italiana, Largo Giulio Onesti 1, 00197 Rome (Italy); Botre, Francesco [Laboratorio Antidoping, Federazione Medico Sportiva Italiana, Largo Giulio Onesti 1, 00197 Rome (Italy); Dipartimento di Management, ' Sapienza' Universita di Roma, Via del Castro Laurenziano 9, 00161 Rome (Italy)

2012-12-05

Highlights: Black-Right-Pointing-Pointer Overall approach for urine samples purification by HPLC for subsequent GC/C/IRMS analysis in doping control. Black-Right-Pointing-Pointer Detection of pseudo-endogenous androgenic steroids (i.e. testosterone, androstenedione) misuse in sports. Black-Right-Pointing-Pointer Routine analysis of steroids by GC/C/IRMS in sports drug testing. - Abstract: The confirmation by GC/C/IRMS of the exogenous origin of pseudo-endogenous steroids from human urine samples requires extracts of adequate purity. A strategy based on HPLC sample purification prior to the GC/C/IRMS analysis of human urinary endogenous androgens (i.e. testosterone, androsterone and/or androstenediols), is presented. A method without any additional derivatization step is proposed, allowing to simplify the urine pretreatment procedure, leading to extracts free of interferences permitting precise and accurate IRMS analysis, without the need of correcting the measured delta values for the contribution of the derivatizing agent. The HPLC extracts were adequately combined to both reduce the number of GC/C/IRMS runs and to have appropriate endogenous reference compounds (ERC; i.e. pregnanediol, 11-keto-etiocholanolone) on each GC-IRMS run. The purity of the extracts was assessed by their parallel analysis by gas chromatography coupled to mass spectrometry, with GC conditions identical to those of the GC/C/IRMS assay. The method has been validated according to ISO17025 requirements (within assay precision below 0.3 Per-Mille-Sign {sup 13}C delta units and between assay precision below 0.6 Per-Mille-Sign {sup 13}C delta units for most of the compounds investigated) fulfilling the World Anti-Doping Agency requirements.

Kas sul on see film juba nähtud? / Jaanus Noormets

Index Scriptorium Estoniae

Noormets, Jaanus

2009-01-01

Gavin Hoodi lavastatud uusim film "X-meeste" sarjast, "X-meeste algus : Wolverine", on enne esilinastust lekkinud internetti. Lühidalt ka teistest aegsalt internetti lekkinud filmidest ja kuidas see neile mõjus

Aggression in children with behavioural/emotional difficulties: seeing aggression on television and video games

OpenAIRE

Mitrofan, O.; Paul, M.; Weich, S.; Spencer, N.

2014-01-01

Background: Mental health professionals are often asked to give advice about managing children’s aggression.\\ud Good quality evidence on contributory environmental factors such as seeing aggression on television and in video\\ud games is relatively lacking, although societal and professional concerns are high. This study investigated possible\\ud associations between seeing aggression in such media and the aggressive behaviour of children attending\\ud specialist outpatient child and adolescent ...

Seeing fearful body language rapidly freezes the observer's motor cortex.

Science.gov (United States)

Borgomaneri, Sara; Vitale, Francesca; Gazzola, Valeria; Avenanti, Alessio

2015-04-01

Fearful body language is a salient signal alerting the observer to the presence of a potential threat in the surrounding environment. Although detecting potential threats may trigger an immediate reduction of motor output in animals (i.e., freezing behavior), it is unclear at what point in time similar reductions occur in the human motor cortex and whether they originate from excitatory or inhibitory processes. Using single-pulse and paired-pulse transcranial magnetic stimulation (TMS), here we tested the hypothesis that the observer's motor cortex implements extremely fast suppression of motor readiness when seeing emotional bodies - and fearful body expressions in particular. Participants observed pictures of body postures and categorized them as happy, fearful or neutral while receiving TMS over the right or left motor cortex at 100-125 msec after picture onset. In three different sessions, we assessed corticospinal excitability, short intracortical inhibition (SICI) and intracortical facilitation (ICF). Independently of the stimulated hemisphere and the time of the stimulation, watching fearful bodies suppressed ICF relative to happy and neutral body expressions. Moreover, happy expressions reduced ICF relative to neutral actions. No changes in corticospinal excitability or SICI were found during the task. These findings show extremely rapid bilateral modulation of the motor cortices when seeing emotional bodies, with stronger suppression of motor readiness when seeing fearful bodies. Our results provide neurophysiological support for the evolutionary notions that emotion perception is inherently linked to action systems and that fear-related cues induce an urgent mobilization of motor reactions. Copyright © 2015 Elsevier Ltd. All rights reserved.

Do blind people see race? Social, legal, and theoretical considerations.

Science.gov (United States)

Obasogie, Osagie K

2010-01-01

Although the meaning, significance, and definition of race have been debated for centuries, one thread of thought unifies almost all of the many diverging perspectives: a largely unquestioned belief that race is self-evident and visually obvious, defined largely by skin color, facial features, and other visual cues. This suggests that “seeing race” is an experience largely unmediated by broader social forces; we simply know it when we see it. It also suggests that those who cannot see are likely to have a diminished understanding of race. But is this empirically accurate?I examine these questions by interviewing people who have been totally blind since birth about race and compare their responses to sighted individuals. I not only find that blind people have as significant an understanding of race as anyone else and that they understand race visually, but that this visual understanding of race stems from interpersonal and institutional socializations that profoundly shape their racial perceptions. These findings highlight how race and racial thinking are encoded into individuals through iterative social practices that train people to think a certain way about the world around them. In short, these practices are so strong that even blind people, in a conceptual sense, “see” race. Rather than being self-evident, these interviews draw attention to how race becomes visually salient through constitutive social practices that give rise to visual understandings of racial difference for blind and sighted people alike. This article concludes with a discussion of these findings' significance for understanding the role of race in law and society.

29 CFR 1918.97 - First aid and lifesaving facilities. (See appendix V of this part).

Science.gov (United States)

2010-07-01

... 29 Labor 7 2010-07-01 2010-07-01 false First aid and lifesaving facilities. (See appendix V of... LONGSHORING General Working Conditions. § 1918.97 First aid and lifesaving facilities. (See appendix V of this... injury, regardless of severity, to the employer. (b) First aid. A first aid kit shall be available at or...

Photonics-Based Microwave Image-Reject Mixer

Directory of Open Access Journals (Sweden)

Dan Zhu

2018-03-01

Full Text Available Recent developments in photonics-based microwave image-reject mixers (IRMs are reviewed with an emphasis on the pre-filtering method, which applies an optical or electrical filter to remove the undesired image, and the phase cancellation method, which is realized by introducing an additional phase to the converted image and cancelling it through coherent combination without phase shift. Applications of photonics-based microwave IRM in electronic warfare, radar systems and satellite payloads are described. The inherent challenges of implementing photonics-based microwave IRM to meet specific requirements of the radio frequency (RF system are discussed. Developmental trends of the photonics-based microwave IRM are also discussed.

Evidence supporting see-and-treat management of cervical intraepithelial neoplasia: a systematic review and meta-analysis

NARCIS (Netherlands)

Ebisch, R.M.F.; Rovers, M.M.; Bosgraaf, R.P.; Pluijm-Schouten, H.W. van der; Melchers, W.J.; Akker, P.A.J. van den; Massuger, L.F.; Bekkers, R.L.M.

2015-01-01

BACKGROUND: Studies of see-and-treat management of cervical intraepithelial neoplasia (CIN) vary in their inclusion criteria, resulting in a broad range of overtreatment rates. OBJECTIVES: To determine overtreatment rates in see-and-treat management of women referred for colposcopy because of

Numerical modeling of supercritical carbon dioxide flow in see-through labyrinth seals

International Nuclear Information System (INIS)

Yuan, Haomin; Pidaparti, Sandeep; Wolf, Mathew; Edlebeck, John; Anderson, Mark

2015-01-01

Highlights: • The supercritical carbon dioxide properties were implemented in an open source CFD code OpenFOAM. • Labyrinth seal was simulated with supercritical carbon dioxide to provide guidance for seal design for compressor. • Two-phase capability was implemented to handle the possible appearance of two-phase carbon dioxide. - Abstract: This paper presents a numerical study of supercritical carbon dioxide (sCO_2) flow in see-through labyrinth seals. The computational fluid dynamic (CFD) simulation of this scenario is performed under the framework of OpenFOAM. Properties of sCO_2 are implemented into OpenFOAM with a user-defined interface. A test facility was constructed to measure the leakage rate and pressure drop of sCO_2 in see-through labyrinth seals. Various designs and conditions have been tested to study the flow characteristic and provide validation data for the numerical model. The primary goal is to verify the model's capability to predict leakage rate, with a secondary goal focused on using the code to optimize the seal design for sCO_2. This research concludes with some guidelines for the see-through labyrinth seal optimization.

Numerical modeling of supercritical carbon dioxide flow in see-through labyrinth seals

Energy Technology Data Exchange (ETDEWEB)

Yuan, Haomin, E-mail: hyuan8@wisc.edu [University of Wisconsin-Madison, 1500 Engineering Drive, Madison, WI 53706 (United States); Pidaparti, Sandeep, E-mail: sandeep.pidaparti@gmail.com [Georgia Institute of Technology, 495 Tech Way NW, CNES Building, Atlanta, GA 30318 (United States); Wolf, Mathew, E-mail: mpwolf44@gmail.com [University of Wisconsin-Madison, 1500 Engineering Drive, Madison, WI 53706 (United States); Edlebeck, John, E-mail: jpedlebeck@gmail.com [University of Wisconsin-Madison, 1500 Engineering Drive, Madison, WI 53706 (United States); Anderson, Mark, E-mail: manderson@engr.wisc.edu [University of Wisconsin-Madison, 1500 Engineering Drive, Madison, WI 53706 (United States)

2015-11-15

Highlights: • The supercritical carbon dioxide properties were implemented in an open source CFD code OpenFOAM. • Labyrinth seal was simulated with supercritical carbon dioxide to provide guidance for seal design for compressor. • Two-phase capability was implemented to handle the possible appearance of two-phase carbon dioxide. - Abstract: This paper presents a numerical study of supercritical carbon dioxide (sCO{sub 2}) flow in see-through labyrinth seals. The computational fluid dynamic (CFD) simulation of this scenario is performed under the framework of OpenFOAM. Properties of sCO{sub 2} are implemented into OpenFOAM with a user-defined interface. A test facility was constructed to measure the leakage rate and pressure drop of sCO{sub 2} in see-through labyrinth seals. Various designs and conditions have been tested to study the flow characteristic and provide validation data for the numerical model. The primary goal is to verify the model's capability to predict leakage rate, with a secondary goal focused on using the code to optimize the seal design for sCO{sub 2}. This research concludes with some guidelines for the see-through labyrinth seal optimization.

Aggression in children with behavioural/emotional difficulties: seeing aggression on television and video games.

Science.gov (United States)

Mitrofan, Oana; Paul, Moli; Weich, Scott; Spencer, Nicholas

2014-11-18

Mental health professionals are often asked to give advice about managing children's aggression. Good quality evidence on contributory environmental factors such as seeing aggression on television and in video games is relatively lacking, although societal and professional concerns are high. This study investigated possible associations between seeing aggression in such media and the aggressive behaviour of children attending specialist outpatient child and adolescent mental health services (CAMHS). In this mixed methods study, forty-seven British children aged 7-11 years with behavioural/emotional difficulties attending CAMHS and their carers participated in a survey; twenty purposively-selected children and a parent/carer of theirs participated in a qualitative study, involving semi-structured interviews, analysed using the Framework Analysis Approach; findings were integrated. Children attending CAMHS exhibit clinically significant aggression, of varying types and frequency. They see aggression in multiple real and virtual settings. Verbal aggression was often seen, frequently exhibited and strongly associated with poor peer relationships and low prosocial behaviour. Children did not think seeing aggression influences their own behaviour but believed it influences others. Carers regarded aggression as resulting from a combination of inner and environmental factors and seeing aggression in real-life as having more impact than television/video games. There is yet no definitive evidence for or against a direct relationship between aggression seen in the media and aggression in children with behavioural/emotional difficulties. Future research should take an ecological perspective, investigating individual, developmental and environmental factors. Carers, professional organisations and policy makers should address aggression seen in all relevant area of children's lives, primarily real-life and secondly virtual environments.

Secure, web-accessible call rosters for academic radiology departments.

Science.gov (United States)

Nguyen, A V; Tellis, W M; Avrin, D E

2000-05-01

Traditionally, radiology department call rosters have been posted via paper and bulletin boards. Frequently, changes to these lists are made by multiple people independently, but often not synchronized, resulting in confusion among the house staff and technical staff as to who is on call and when. In addition, multiple and disparate copies exist in different sections of the department, and changes made would not be propagated to all the schedules. To eliminate such difficulties, a paperless call scheduling application was developed. Our call scheduling program allowed Java-enabled web access to a database by designated personnel from each radiology section who have privileges to make the necessary changes. Once a person made a change, everyone accessing the database would see the modification. This eliminates the chaos resulting from people swapping shifts at the last minute and not having the time to record or broadcast the change. Furthermore, all changes to the database were logged. Users are given a log-in name and password and can only edit their section; however, all personnel have access to all sections' schedules. Our applet was written in Java 2 using the latest technology in database access. We access our Interbase database through the DataExpress and DB Swing (Borland, Scotts Valley, CA) components. The result is secure access to the call rosters via the web. There are many advantages to the web-enabled access, mainly the ability for people to make changes and have the changes recorded and propagated in a single virtual location and available to all who need to know.

Estimating Structural Models of Corporate Bond Prices in Indonesian Corporations

Directory of Open Access Journals (Sweden)

Lenny Suardi

2014-08-01

Full Text Available This  paper  applies  the  maximum  likelihood  (ML  approaches  to  implementing  the structural  model  of  corporate  bond,  as  suggested  by  Li  and  Wong  (2008,  in  Indonesian corporations.  Two  structural  models,  extended  Merton  and  Longstaff  &  Schwartz  (LS models,  are  used  in  determining  these  prices,  yields,  yield  spreads  and  probabilities  of default. ML estimation is used to determine the volatility of irm value. Since irm value is unobserved variable, Duan (1994 suggested that the irst step of ML estimation is to derive the likelihood function for equity as the option on the irm value. The second step is to ind parameters such as the drift and volatility of irm value, that maximizing this function. The irm value itself is extracted by equating the pricing formula to the observed equity prices. Equity,  total  liabilities,  bond  prices  data  and  the  irm's  parameters  (irm  value,  volatility of irm value, and default barrier are substituted to extended Merton and LS bond pricing formula in order to valuate the corporate bond.These models are implemented to a sample of 24 bond prices in Indonesian corporation during  period  of  2001-2005,  based  on  criteria  of  Eom,  Helwege  and  Huang  (2004.  The equity  and  bond  prices  data  were  obtained  from  Indonesia  Stock  Exchange  for  irms  that issued equity and provided regular inancial statement within this period. The result shows that both models, in average, underestimate the bond prices and overestimate the yields and yield spread. ";} // -->activate javascript

The influence of different referencing methods on the accuracy of δ(13) C value measurement of ethanol fuel by gas chromatography/combustion/isotope ratio mass spectrometry.

Science.gov (United States)

Neves, Laura A; Rodrigues, Janaína M; Daroda, Romeu J; Silva, Paulo R M; Ferreira, Alexandre A; Aranda, Donato A G; Eberlin, Marcos N; Fasciotti, Maíra

2015-11-15

Brazil is the largest producer of sugar cane bioethanol in the world. Isotope ratio mass spectrometry (IRMS) is the technique of choice to certify the origin/raw materials for ethanol production, but the lack of certified reference materials (CRMs) for accurate measurements of δ(13) C values traceable to Vienna Pee Dee Belemnite (VPDB), the international zero point for (13) C/(12) C measurements, certified and compatible with gas chromatography (GC)/IRMS instruments may compromise the accuracy of δ(13) C determinations. We evaluated the influence of methods for the calibration and normalization of raw δ(13) C values of ethanol samples. Samples were analyzed by GC/C/IRMS using two different GC columns. Different substances were used as isotopic standards for the working gas calibration. The δ(13) C values obtained with the three methods of normalization were statistically compared with those obtained with elemental analyzer (EA)/IRMS, since the δ(13) C results obtained using EA are traceable to VPDB via the NBS 22 reference material. It was observed that both the isotopic reference material for CO2 calibration and the GC column have a major effect on the δ(13) C measurements, leading to a bias of almost 2-3 ‰ in the δ(13) C values. All three methods of normalization were equivalent in performance, enabling an improvement in the GC/C/IRMS accuracy, compared with the EA/IRMS reference values for the samples. All the methods of CO2 calibration, chromatography and normalization presented in this work demonstrated several sources of traceability and accuracy loss for the determination of δ(13) C values in ethanol fuel samples by GC/C/IRMS. This work has also shown the importance of using proper CRMs traceable to VPBD that should be compatible and certified using GC/C/IRMS, ideally in a wide range of δ(13) C values. This is important not only for bioethanol fuel samples, but also for many analytes commonly analyzed by IRMS. Copyright © 2015 John Wiley & Sons

SEE-GRID eInfrastructure for Regional eScience

Science.gov (United States)

Prnjat, Ognjen; Balaz, Antun; Vudragovic, Dusan; Liabotis, Ioannis; Sener, Cevat; Marovic, Branko; Kozlovszky, Miklos; Neagu, Gabriel

In the past 6 years, a number of targeted initiatives, funded by the European Commission via its information society and RTD programmes and Greek infrastructure development actions, have articulated a successful regional development actions in South East Europe that can be used as a role model for other international developments. The SEEREN (South-East European Research and Education Networking initiative) project, through its two phases, established the SEE segment of the pan-European G ´EANT network and successfully connected the research and scientific communities in the region. Currently, the SEE-LIGHT project is working towards establishing a dark-fiber backbone that will interconnect most national Research and Education networks in the region. On the distributed computing and storage provisioning i.e. Grid plane, the SEE-GRID (South-East European GRID e-Infrastructure Development) project, similarly through its two phases, has established a strong human network in the area of scientific computing and has set up a powerful regional Grid infrastructure, and attracted a number of applications from different fields from countries throughout the South-East Europe. The current SEEGRID-SCI project, ending in April 2010, empowers the regional user communities from fields of meteorology, seismology and environmental protection in common use and sharing of the regional e-Infrastructure. Current technical initiatives in formulation are focusing on a set of coordinated actions in the area of HPC and application fields making use of HPC initiatives. Finally, the current SEERA-EI project brings together policy makers - programme managers from 10 countries in the region. The project aims to establish a communication platform between programme managers, pave the way towards common e-Infrastructure strategy and vision, and implement concrete actions for common funding of electronic infrastructures on the regional level. The regional vision on establishing an e

Making Things See 3D vision with Kinect, Processing, Arduino, and MakerBot

CERN Document Server

Borenstein, Greg

2012-01-01

This detailed, hands-on guide provides the technical and conceptual information you need to build cool applications with Microsoft's Kinect, the amazing motion-sensing device that enables computers to see. Through half a dozen meaty projects, you'll learn how to create gestural interfaces for software, use motion capture for easy 3D character animation, 3D scanning for custom fabrication, and many other applications. Perfect for hobbyists, makers, artists, and gamers, Making Things See shows you how to build every project with inexpensive off-the-shelf components, including the open source P

Professor Eric Can't See: A Project-Based Learning Case for Neurobiology Students.

Science.gov (United States)

Ogilvie, Judith Mosinger; Ribbens, Eric

2016-01-01

"Professor Eric Can't See" is a semi-biographical case study written for an upper level undergraduate Neurobiology of Disease course. The case is integrated into a unit using a project-based learning approach to investigate the retinal degenerative disorder Retinitis pigmentosa and the visual system. Some case study scenes provide specific questions for student discussion and problem-based learning, while others provide background for student inquiry and related active learning exercises. The case was adapted from "'Chemical Eric' Can't See," and could be adapted for courses in general neuroscience or sensory neuroscience.

Metallurgy Department

DEFF Research Database (Denmark)

Risø National Laboratory, Roskilde

The activities of the Metallurgy Department at Risø during 1981 are described. The work is presented in three chapters: General Materials Research, Technology and Materials Development, Fuel Elements. Furthermore, a survey is given of the department's participation in international collaboration...

Role of pH Changes on Transforming Growth Factor-β1 Release and on the Fibrin Architecture of Platelet-rich Fibrin When Layered with Biodentine, Glass Ionomer Cement, and Intermediate Restorative Material.

Science.gov (United States)

Mullaguri, Harish; Suresh, Nandini; Surendran, Smitha; Velmurugan, Natanasabapathy; Chitra, Selvarajan

2016-05-01

The purpose of this study was to evaluate the influence of pH that is due to setting reaction of Biodentine, glass ionomer cement (GIC), and intermediate restorative material (IRM) on transforming growth factor-β1 (TGF-β1) release and on the fibrin architecture of platelet-rich fibrin (PRF). PRF was obtained from 8 volunteers and layered over the freshly prepared GIC, IRM, and Biodentine mixtures. TGF-β1 release was estimated by using enzyme-linked immunosorbent assay (ELISA), and fibrin structure of PRF was analyzed by using scanning electron microscope at 1 and 5 hours. Biodentine, GIC, and IRM increased the TGF-β1 release in comparison with that of control group (PRF alone) at both 1 and 5 hours. Biodentine released significantly more TGF-β1 than GIC and IRM at 1 hour. At 5 hours both GIC and Biodentine released significantly more TGF-β1 than IRM. The fibrin architecture of the Biodentine group was similar to that of control group at both 1 and 5 hours. In GIC and IRM groups the fibrillar structure of fibrin was collapsed, ill-defined, and cloudy with very thick fibers and irregularly reduced porosities. Biodentine induces larger amount of TGF-β1 release and also maintains the integrity of fibrin structure when compared with GIC and IRM when layered over PRF. Copyright © 2016 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

Resources from waste : integrated resource management phase 1 study report

International Nuclear Information System (INIS)

Corps, C.; Salter, S.; Lucey, P.; O'Riordan, J.

2008-01-01

Integrated resource management (IRM) of municipal waste streams and water systems requires a structured analysis of options that consider environmental aspects such as greenhouse gases, carbon taxes and credits. Each option's inputs and outputs are assessed to determine the net highest and best use and value. IRM focuses on resource recovery and extracting maximum value. It considers the overall net impact on the taxpayer and requires the integration of liquid and solid waste streams to maximize values for recovering energy in the form of biofuels, heat, minerals, water and reducing electricity demand. IRM is linked to water management through reuse of treated water for groundwater recharge and to offset potable water use for non-potable purposes such as irrigation, including potential commercial use, which contributes to maintaining or improving the health of watersheds. This report presented a conceptual design for the application of IRM in the province of British Columbia (BC) and analyzed its potential contribution to the provincial climate change agenda. The report discussed traditional waste management, the IRM approach, and resource recovery technology and opportunities. The business case for IRM in BC was also outlined. It was concluded that IRM has the potential to be a viable solution to water, solid and liquid waste management that should be less expensive, result in fewer environmental impacts, and provide greater flexibility than traditional approaches to waste management. 63 refs., 17 tabs., 21 figs., 10 appendices

Effects of body-color mutations on vitality: an attempt to establish easy-to-breed see-through medaka strains by outcrossing.

Science.gov (United States)

Ohshima, Ayaka; Morimura, Noriko; Matsumoto, Chizuru; Hiraga, Ami; Komine, Ritsuko; Kimura, Tetsuaki; Naruse, Kiyoshi; Fukamachi, Shoji

2013-09-04

"See-through" strains of medaka are unique tools for experiments: their skin is transparent, and their internal organs can be externally monitored throughout life. However, see-through fish are less vital than normally pigmented wild-type fish, which allows only skilled researchers to make the most of their advantages. Expecting that hybrid vigor (heterosis) would increase the vitality, we outcrossed two see-through strains (SK(2) and STIII) with a genetically distant wild-type strain (HNI). Fish with the see-through phenotypes were successfully restored in the F2 generation and maintained as closed colonies. We verified that genomes of these hybrid see-through strains actually consisted of approximately 50% HNI and approximately 50% SK(2) or STIII alleles, but we could not obtain evidence supporting improved survival of larvae or fecundity of adults, at least under our breeding conditions. We also found that four of the five see-through mutations (b(g8), i-3, gu, and il-1 but not lf) additively decrease viability. Given that heterosis could not overwhelm the viability-reducing effects of the see-through mutations, easy-to-breed see-through strains will only be established by other methods such as conditional gene targeting or screening of new body-color mutations that do not reduce viability.

Remote handling concept for the neutral beam system

International Nuclear Information System (INIS)

Choi, Chang-Hwan; Palmer, Jim; Conesa, Carles; Friconneau, Jean-Pierre; Martins, Jean-Pierre; Subramanian, Rajendran; Jeannoutot, Thomas; Graceffa, Joseph; Schunke, Beatrix; Uffelen, MarcoVan; Damiani, Carlo; Tesini, Alessandro

2011-01-01

The NB ITER Remote Maintenance System (NB IRMS) provides the means for the remote maintenance within the NB Cell by removal and replacement of the plant equipment. The NB IRMS will be installed and removed with the assistance of human workers during the preparation, and post-operation phase. During the maintenance operation after opening the Passive Magnetic Shield (PMS) and vessels, the maintenance activity and recovery from failure should be conducted remotely. This paper describes the concept design of the NB IRMS operating inside the NB cell for maintenance of the plant equipment such as NB components, and Upper Port Plugs (UPP). The main tasks of the IRMS, the description of the sub-systems and their specification, and deployment/operation principles are presented. The transportation concept of the NB IRMS to the hot cell facility for storage and maintenance is presented, which is to avoid unnecessary exposure on the equipment inside the NB cell during the machine operation.

Differentiation of Organically and Conventionally Grown Tomatoes by Chemometric Analysis of Combined Data from Proton Nuclear Magnetic Resonance and Mid-infrared Spectroscopy and Stable Isotope Analysis.

Science.gov (United States)

Hohmann, Monika; Monakhova, Yulia; Erich, Sarah; Christoph, Norbert; Wachter, Helmut; Holzgrabe, Ulrike

2015-11-04

Because the basic suitability of proton nuclear magnetic resonance spectroscopy ((1)H NMR) to differentiate organic versus conventional tomatoes was recently proven, the approach to optimize (1)H NMR classification models (comprising overall 205 authentic tomato samples) by including additional data of isotope ratio mass spectrometry (IRMS, δ(13)C, δ(15)N, and δ(18)O) and mid-infrared (MIR) spectroscopy was assessed. Both individual and combined analytical methods ((1)H NMR + MIR, (1)H NMR + IRMS, MIR + IRMS, and (1)H NMR + MIR + IRMS) were examined using principal component analysis (PCA), partial least squares discriminant analysis (PLS-DA), linear discriminant analysis (LDA), and common components and specific weight analysis (ComDim). With regard to classification abilities, fused data of (1)H NMR + MIR + IRMS yielded better validation results (ranging between 95.0 and 100.0%) than individual methods ((1)H NMR, 91.3-100%; MIR, 75.6-91.7%), suggesting that the combined examination of analytical profiles enhances authentication of organically produced tomatoes.

On-line gas chromatography combustion/pyrolysis isotope ratio mass spectrometry (HRGC-C/P-IRMS) of pineapple (Ananas comosus L. Merr.) volatiles.

Science.gov (United States)

Preston, Christina; Richling, Elke; Elss, Sandra; Appel, Markus; Heckel, Frank; Hartlieb, Ariane; Schreier, Peter

2003-12-31

By use of extracts prepared by liquid-liquid separation of the volatiles from self-prepared juices of pineapple fruits (Ananas comosus) (n = 14) as well as commercial pineapple recovery aromas/water phases (n = 3), on-line capillary gas chromatography-isotope ratio mass spectrometry was employed in the combustion (C) and the pyrolysis (P) modes (HRGC-C/P-IRMS) to determine the delta(13)C(VPDB) and delta(2)H(VSMOW) values of selected pineapple flavor constituents. In addition to methyl 2-methylbutanoate 1, ethyl 2-methylbutanoate 2, methyl hexanoate 3, ethyl hexanoate 4, and 2,5-dimethyl-4-methoxy-3[2H]-furanone 5, each originating from the fruit, the delta(13)C(VPDB) and delta(2)H(VSMOW) data of commercial synthetic 1-5 and "natural" (biotechnologically derived) 1-4 were determined. With delta(13)C(VPDB) data of pineapple volatiles 1-4 varying from -12.8 to -24.4 per thousand, the range expected for CAM metabolism was observed. Compound 5 showed higher depletion from -20.9 to -28.6 per thousand. A similar situation was given for the delta(2)H(VSMOW) values of 3-5 from pineapple ranging from -118 to -191 per thousand, whereas 1 and 2 showed higher depleted values from -184 to -263 per thousand. In nearly all cases, analytical differentiation of 1-5 from pineapple and natural as well as synthetic origin was possible. In general, natural and synthetic 1-5 exhibited delta(13)C(VPDB) data ranging from -11.8 to -32.2 per thousand and -22.7 to -35.9 per thousand, respectively. Their delta(2)H(VSMOW) data were in the range from -242 to -323 per thousand and -49 to -163 per thousand, respectively.

76 FR 50752 - Proposed Information Collection; Comment Request for the Landslide Report: Did You See It?

Science.gov (United States)

2011-08-16

... Collection; Comment Request for the Landslide Report: Did You See It? AGENCY: United States Geological Survey... the USGS Landslide Hazards Program's Landslide Report: Did You See It? As required by the Paperwork... information unless it displays a currently valid OMB control number. DATES: You must submit comments on or...

Strategy: Siemens sees green - Siemens after the atom

International Nuclear Information System (INIS)

Moragues, M.; Dupin, L.; Scherer, M.

2011-01-01

This article discusses the new strategy implemented by Peter Loescher, the Siemens' CEO, who has just announced that Siemens decided to stop working directly for the nuclear sector, and to be a pioneer in sustainable development. This means a reorganisation of this group which, beside its energy department, its industry department and health department, comprises an infrastructures and cities' department which gathers rail, electricity distribution, building technologies. It also means important investments in the renewable energy sector, and phasing out of the automotive, telecommunications and data processing hardware sectors. The challenges, opportunities, strengths and weaknesses of Siemens four pillars (energy, industry, health, and infrastructures) are discussed. An article also evokes the relationship of Siemens with the French nuclear industry

Development Of An In Situ Passive Sampler For The Detection And Remediation of Explosive Compounds

Science.gov (United States)

2016-06-07

including high performance liquid chromatography (HPLC), gas chromatography mass spectrometry (GCMS) and isotope ratio mass spectrometry ( IRMS ) as...GCMS) and isotope ratio mass spectrometry ( IRMS ) as summarized in St. George et al., 2010 and Smith et al., 2013, 2014. Depuration rates will be...TNT and RDX for the depuration compounds and unlabeled compounds in the ambient environment. These will be quantified as above by GCMS and IRMS . 2015

Initial Testing for the Recommendation of Improved Gas Metal Arc Welding Procedures for HY-80 Steel Plate Butt Joints at Norfolk Naval Shipyard

Science.gov (United States)

2015-12-01

17  Figure 11.  IRMS versus VRMS Comparison with Different Ar/CO2 Gas Mixtures Using GMAW-P...21  Figure 13.  IRMS versus VRMS Comparison with Miller and Lincoln Welding Machines in the Horizontal and Vertical Positions Using GMAW-P...Gas Metal Arc Welding Pulsed Spray Transfer GMAW-S Gas Metal Arc Welding Spray Transfer HAZ Heat Affected Zone HC#1 Hull Cut #1 IRMS Current Root

Development of an enantiomer-specific stable carbon isotope analysis (ESIA) method for assessing the fate of α-hexachlorocyclo-hexane in the environment.

Science.gov (United States)

Badea, Silviu-Laurentiu; Vogt, Carsten; Gehre, Matthias; Fischer, Anko; Danet, Andrei-Florin; Richnow, Hans-Hermann

2011-05-30

α-Hexachlorocyclohexane (α-HCH) is the only chiral isomer of the eight 1,2,3,4,5,6-HCHs and we have developed an enantiomer-specific stable carbon isotope analysis (ESIA) method for the evaluation of its fate in the environment. The carbon isotope ratios of the α-HCH enantiomers were determined for a commercially available α-HCH sample using a gas chromatography-combustion-isotope ratio mass spectrometry (GC-C-IRMS) system equipped with a chiral column. The GC-C-IRMS measurements revealed δ-values of -32.5 ± 0.8‰ and -32.3 ± 0.5‰ for (-) α-HCH and (+) α-HCH, respectively. The isotope ratio of bulk α-HCH was estimated to be -32.4 ± 0.6‰ which was in accordance with the δ-values obtained by GC-C-IRMS (-32.7 ± 0.2‰) and elemental analyzer-isotope ratio mass spectrometry (EA-IRMS) of the bulk α-HCH (-32.1 ± 0.1‰). The similarity of the isotope ratio measurements of bulk α-HCH by EA-IRMS and GC-C-IRMS indicates the accuracy of the chiral GC-C-IRMS method. The linearity of the α-HCH ESIA method shows that carbon isotope ratios can be obtained for a signal size above 100 mV. The ESIA measurements exhibited standard deviations (2σ) that were mostly IRMS method, the isotope compositions of individual enantiomers in biodegradation experiments of α-HCH with Clostridium pasteurianum and samples from a contaminated field site were determined. The isotopic compositions of the α-HCH enantiomers show a range of enantiomeric and isotope patterns, suggesting that enantiomeric and isotope fractionation can serve as an indicator for biodegradation and source characterization of α-HCH in the environment. Copyright © 2011 John Wiley & Sons, Ltd.

Existing and emerging technologies for measuring stable isotope labelled retinol in biological samples: isotope dilution analysis of body retinol stores.

Science.gov (United States)

Preston, Tom

2014-01-01

This paper discusses some of the recent improvements in instrumentation used for stable isotope tracer measurements in the context of measuring retinol stores, in vivo. Tracer costs, together with concerns that larger tracer doses may perturb the parameter under study, demand that ever more sensitive mass spectrometric techniques are developed. GCMS is the most widely used technique. It has high sensitivity in terms of sample amount and uses high resolution GC, yet its ability to detect low isotope ratios is limited by background noise. LCMSMS may become more accessible for tracer studies. Its ability to measure low level stable isotope tracers may prove superior to GCMS, but it is isotope ratio MS (IRMS) that has been designed specifically for low level stable isotope analysis through accurate analysis of tracer:tracee ratios (the tracee being the unlabelled species). Compound-specific isotope analysis, where GC is interfaced to IRMS, is gaining popularity. Here, individual 13C-labelled compounds are separated by GC, combusted to CO2 and transferred on-line for ratiometric analysis by IRMS at the ppm level. However, commercially-available 13C-labelled retinol tracers are 2 - 4 times more expensive than deuterated tracers. For 2H-labelled compounds, GC-pyrolysis-IRMS has now become more generally available as an operating mode on the same IRMS instrument. Here, individual compounds are separated by GC and pyrolysed to H2 at high temperature for analysis by IRMS. It is predicted that GC-pyrolysis-IRMS will facilitate low level tracer procedures to measure body retinol stores, as has been accomplished in the case of fatty acids and amino acids. Sample size requirements for GC-P-IRMS may exceed those of GCMS, but this paper discusses sample preparation procedures and predicts improvements, particularly in the efficiency of sample introduction.

Cervical cancer prevention program in Jakarta, Indonesia: See and Treat model in developing country

OpenAIRE

Nuranna, Laila; Aziz, Mohamad Farid; Cornain, Santoso; Purwoto, Gatot; Purbadi, Sigit; Budiningsih, Setyawati; Siregar, Budiningsih; Peters, Alexander Arnold Willem

2012-01-01

Objective The purpose of this study was to describe the implementation of single visit approach or See-visual inspection of the cervix with acetic acid (VIA)-and Treat-immediate cryotherapy in the VIA positive cases-model for the cervical cancer prevention in Jakarta, Indonesia. Methods An observational study in community setting for See and Treat program was conducted in Jakarta from 2007 until 2010. The program used a proactive and coordinative with VIA and cryotherapy (Proactive-VO) model ...

Framework See-Think as a Tool for Crowdsourcing Support - Case Study on Crisis Management

Science.gov (United States)

Netek, R.; Panek, J.

2016-06-01

See-Think-Do is a framework originally used as an approach focused on a service and product marketing on the Internet. Customers can be classified into three groups according to their involvement from potential users to real customers. The article presents an idea of public involvement in community mapping in three levels: "See"—almost any user; "Think"—potential contributors; and "Do"—interested users. The case study implements the See-Think-Do framework as an awareness-based approach used for The Crisis Map of the Czech Republic. It is an Ushahidi-based crowdsourcing platform for sharing spatial and multimedia information during crisis situations, e.g. disaster floods in 2013. While the current crisis projects use public mapping just at the onset of the disaster, according to See-Think-Do any user can be considered as a potential contributor even during the dormant period. The focus is put on the "See" and "Think" groups of contributors, which are currently ignored. The objective of this paper is to summarize approaches (social networks, mass-media, emailing, gamification, …) and tools (GIT/GIS, ICT, multimedia) for increasing the awareness about the project within the resting phase. That recruits a higher number of both active and passive users during the disaster. It allows the training in ICT, cartographical, spatial and GIS skills in a non-stressful way and the targeting on specific operators. Volunteers from the "Think" group may be used for data processing or rectification, GIS professionals from the "Do" group for data verification. The results refer that contributors with already established skills and required literacy (interface, data uploading) provide data faster and more accurate, the usability of the project increases based on users' comments.

SeeCoast: persistent surveillance and automated scene understanding for ports and coastal areas

Science.gov (United States)

Rhodes, Bradley J.; Bomberger, Neil A.; Freyman, Todd M.; Kreamer, William; Kirschner, Linda; L'Italien, Adam C.; Mungovan, Wendy; Stauffer, Chris; Stolzar, Lauren; Waxman, Allen M.; Seibert, Michael

2007-04-01

SeeCoast is a prototype US Coast Guard port and coastal area surveillance system that aims to reduce operator workload while maintaining optimal domain awareness by shifting their focus from having to detect events to being able to analyze and act upon the knowledge derived from automatically detected anomalous activities. The automated scene understanding capability provided by the baseline SeeCoast system (as currently installed at the Joint Harbor Operations Center at Hampton Roads, VA) results from the integration of several components. Machine vision technology processes the real-time video streams provided by USCG cameras to generate vessel track and classification (based on vessel length) information. A multi-INT fusion component generates a single, coherent track picture by combining information available from the video processor with that from surface surveillance radars and AIS reports. Based on this track picture, vessel activity is analyzed by SeeCoast to detect user-defined unsafe, illegal, and threatening vessel activities using a rule-based pattern recognizer and to detect anomalous vessel activities on the basis of automatically learned behavior normalcy models. Operators can optionally guide the learning system in the form of examples and counter-examples of activities of interest, and refine the performance of the learning system by confirming alerts or indicating examples of false alarms. The fused track picture also provides a basis for automated control and tasking of cameras to detect vessels in motion. Real-time visualization combining the products of all SeeCoast components in a common operating picture is provided by a thin web-based client.

Kuum IT-trend 2007 - see oled sina ise! / Andrus Hiiepuu, Ants Sild

Index Scriptorium Estoniae

Hiiepuu, Andrus, 1966-

2007-01-01

Ajakiri Time kuulutas aasta inimeseks tavalise arvutikasutaja, autorid arutlevad, mida see sina ise IT-vallas võiks tähendada. Infotainment - infotehnoloogia -ja kommunikatsioonivahendite ning meelelahutuse sulandumine

100 Area source operable unit focused feasibility study report. Draft A

International Nuclear Information System (INIS)

1994-09-01

In accordance with the Hanford Past-Practice Strategy (HPPS), a focused feasibility study (FFS) is performed for those waste sites which have been identified as candidates for interim remedial measures (IRM) based on information contained in applicable work plans and limited field investigations (LFI). The FFS process for the 100 Area source operable units will be conducted in two stages. This report, hereafter referred to as the Process Document, documents the first stage of the process. In this stage, IRM alternatives are developed and analyzed on the basis of waste site groups associated with the 100 Area source operable units. The second stage, site-specific evaluation of the IRM alternatives presented in this Process Document, is documented in a series of operable unit-specific reports. The objective of the FFS (this Process Document and subsequent operable unit-specific reports) is to provide decision makers with sufficient information to allow appropriate and timely selection of IRM for sites associated with the 100 Area source operable units. Accordingly, the following information is presented: a presentation of remedial action objectives; a description of 100 Area waste site groups and associated group profiles; a description of IRM alternatives; and detailed and comparative analyses of the IRM alternatives

Radiative see-saw formula in nonsupersymmetric SO (10) with dark ...

Indian Academy of Sciences (India)

In the absence of supersymmetry, we show how experimentally verifiable radiative see-saw formula of Ma type is realized in non-SUSY (10) while fulfilling the twin objectives: precision gauge coupling unification and dark matter. This model is expected to have a dramatic impact on neutrino physics, dark matter and all ...

See, Say, Write: A Writing Routine for the Preschool Classroom

Science.gov (United States)

Copp, Stefanie B.; Cabell, Sonia Q.; Tortorelli, Laura S.

2016-01-01

See, Say, Write is an adaptable classroom writing routine that teachers can use across a range of activities in the preschool classroom. This preschool writing routine offers an opportunity for teachers to build on a shared experience through engagement in rich conversation and writing. After a shared experience, teachers will provide a visual…

Research Culture in Higher Education: The Case of a Foreign Language Department in Mexico

Directory of Open Access Journals (Sweden)

Edith Hernández Méndez

2014-10-01

Full Text Available In the case of Mexico, until recently, many universities focused mainly on teaching, but recent changes have led to new appointments in research, administration, and community service. There now seems to be, however, a view of the predominance of research in the academic environment. Therefore, the purpose of this paper was to examine and identify, through the lens of organizational theory and a current model of research culture in an academic setting, some characteristics of the research culture in the Department of Languages and Education at a public university in Southeast Mexico. Following the international tendencies and models in higher education, we see that the research culture observed in this university resembles more a market culture than other types of culture, although some traits of hierarchy culture provide cohesion in the organization.

Pilot-scale treatability test plan for the 200-BP-5 operable unit

International Nuclear Information System (INIS)

1994-08-01

This document presents the treatability test plan for pilot-scale pump and treat testing at the 200-BP-5 Operable Unit. This treatability test plan has been prepared in response to an agreement between the U.S. Department of Energy (DOE), the U.S. Environmental Protection Agency (EPA), and the State of Washington Department of Ecology (Ecology), as documented in Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement, Ecology et al. 1989a) Change Control Form M-13-93-03 (Ecology et al. 1994) and a recent 200 NPL Agreement Change Control Form (Appendix A). The agreement also requires that, following completion of the activities described in this test plan, a 200-BP-5 Operable Unit Interim Remedial Measure (IRM) Proposed Plan be developed for use in preparing an Interim Action Record of Decision (ROD). The IRM Proposed Plan will be supported by the results of this treatability test plan, as well as by other 200-BP-5 Operable Unit activities (e.g., development of a qualitative risk assessment). Once issued, the Interim Action ROD will specify the interim action(s) for groundwater contamination at the 200-BP-5 Operable Unit. The treatability test approach is to conduct a pilot-scale pump and treat test for each of the two contaminant plumes associated with the 200-BP-5 Operable Unit. Primary contaminants of concern are 99 Tc and 60 Co for underwater affected by past discharges to the 216-BY Cribs, and 90 Sr, 239/240 Pu, and Cs for groundwater affected by past discharges to the 216-B-5 Reverse Well. The purpose of the pilot-scale treatability testing presented in this testplan is to provide the data basis for preparing an IRM Proposed Plan. To achieve this objective, treatability testing must: Assess the performance of groundwater pumping with respect to the ability to extract a significant amount of the primary contaminant mass present in the two contaminant plumes

Physicians in Postgraduate Training Characteristics and Support of Palliative Sedation for Existential Distress.

Science.gov (United States)

Cripe, Larry D; Perkins, Susan M; Cottingham, Ann; Tong, Yan; Kozak, Mary Ann; Mehta, Rakesh

2017-09-01

Palliative sedation for refractory existential distress (PS-ED) is ethically troubling but potentially critical to quality end-of-life (EOL) care. Physicians' in postgraduate training support toward PS-ED is unknown nor is it known how empathy, hope, optimism, or intrinsic religious motivation (IRM) affect their support. These knowledge gaps hinder efforts to support physicians who struggle with patients' EOL care preferences. One hundred thirty-four postgraduate physicians rated their support of PS for refractory physical pain (PS-PP) or PS-ED, ranked the importance of patient preferences in ethically challenging situations, and completed measures of empathy, hope, optimism, and IRM. Predictors of PS-ED and PS-PP support were examined using binary and multinomial logistic regression. Only 22.7% of residents were very supportive of PS-ED, and 82.0% were very supportive of PS-PP. Support for PS-PP or PS-ED did not correlate with levels of empathy, hope, optimism, or IRM; however, for residents with lower IRM, greater optimism was associated with greater PS-ED support. In contrast, among residents with higher IRM, optimism was not associated with PS-ED support. Comparing current results to published surveys, a similar proportion of residents and practicing physicians support PS-ED and PS-PP. In contrast to practicing physicians, however, IRM does not directly influence residents' supportiveness. The interaction between optimism and IRM suggests residents' beliefs and characteristics are salient to their EOL decisions. End-of-life curricula should provide physicians opportunities to reflect on the personal and ethical factors that influence their support for PS-ED.

Laser Imaging Video Camera Sees Through Fire, Fog, Smoke

Science.gov (United States)

2015-01-01

Under a series of SBIR contracts with Langley Research Center, inventor Richard Billmers refined a prototype for a laser imaging camera capable of seeing through fire, fog, smoke, and other obscurants. Now, Canton, Ohio-based Laser Imaging through Obscurants (LITO) Technologies Inc. is demonstrating the technology as a perimeter security system at Glenn Research Center and planning its future use in aviation, shipping, emergency response, and other fields.

Does better access to FPs decrease the likelihood of emergency department use?

Science.gov (United States)

Mian, Oxana; Pong, Raymond

2012-01-01

Abstract Objective To determine whether better access to FP services decreases the likelihood of emergency department (ED) use among the Ontario population. Design Population-based telephone survey. Setting Ontario. Participants A total of 8502 Ontario residents aged 16 years and older. Main outcome measures Emergency department use in the 12 months before the survey. Results Among the general population, having a regular FP was associated with having better access to FPs for immediate care (P FPs for immediate care at least once a year; 63.1% of them had seen FPs without difficulties and were significantly less likely to use EDs than those who did not see FPs or had difficulties accessing physicians when needed (OR = 0.62, P FPs (P FPs for immediate care among the general population. Further research is needed to understand what accounts for a higher likelihood of ED use among those with regular FPs, new immigrants, residents of northern and rural areas of Ontario, and people with low socioeconomic status when actual access and sociodemographic characteristics have been taken into consideration. More important, this study demonstrates a need of distinguishing between potential and actual access to care, as having a regular FP and having timely and effective access to FP care might mean different things and have different effects on ED use. PMID:23152473

Measurements of electroweak [Formula: see text] production and constraints on anomalous gauge couplings with the ATLAS detector.

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Aaboud, M; Aad, G; Abbott, B; Abdallah, J; Abdinov, O; Abeloos, B; Abidi, S H; AbouZeid, O S; Abraham, N L; Abramowicz, H; Abreu, H; Abreu, R; Abulaiti, Y; Acharya, B S; Adachi, S; Adamczyk, L; Adams, D L; Adelman, J; Adersberger, M; Adye, T; Affolder, A A; Agatonovic-Jovin, T; Agheorghiesei, C; Aguilar-Saavedra, J A; Ahlen, S P; Ahmadov, F; Aielli, G; Akatsuka, S; Akerstedt, H; Åkesson, T P A; Akimov, A V; Alberghi, G L; Albert, J; Alconada Verzini, M J; Aleksa, M; Aleksandrov, I N; Alexa, C; Alexander, G; Alexopoulos, T; Alhroob, M; Ali, B; Aliev, M; Alimonti, G; Alison, J; Alkire, S P; Allbrooke, B M M; Allen, B W; Allport, P P; Aloisio, A; Alonso, A; Alonso, F; Alpigiani, C; Alshehri, A A; Alstaty, M; Alvarez Gonzalez, B; Piqueras, D Álvarez; Alviggi, M G; Amadio, B T; Amaral Coutinho, Y; Amelung, C; Amidei, D; Santos, S P Amor Dos; Amorim, A; Amoroso, S; Amundsen, G; Anastopoulos, C; Ancu, L S; Andari, N; Andeen, T; Anders, C F; Anders, J K; Anderson, K J; Andreazza, A; Andrei, V; 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Tripiana, M F; Trischuk, W; Trocmé, B; Trofymov, A; Troncon, C; Trottier-McDonald, M; Trovatelli, M; Truong, L; Trzebinski, M; Trzupek, A; Tsang, K W; Tseng, J C-L; Tsiareshka, P V; Tsipolitis, G; Tsirintanis, N; Tsiskaridze, S; Tsiskaridze, V; Tskhadadze, E G; Tsui, K M; Tsukerman, I I; Tsulaia, V; Tsuno, S; Tsybychev, D; Tu, Y; Tudorache, A; Tudorache, V; Tulbure, T T; Tuna, A N; Tupputi, S A; Turchikhin, S; Turgeman, D; Turk Cakir, I; Turra, R; Tuts, P M; Ucchielli, G; Ueda, I; Ughetto, M; Ukegawa, F; Unal, G; Undrus, A; Unel, G; Ungaro, F C; Unno, Y; Unverdorben, C; Urban, J; Urquijo, P; Urrejola, P; Usai, G; Usui, J; Vacavant, L; Vacek, V; Vachon, B; Valderanis, C; Valdes Santurio, E; Valencic, N; Valentinetti, S; Valero, A; Valéry, L; Valkar, S; Vallier, A; Valls Ferrer, J A; Van Den Wollenberg, W; van der Graaf, H; van Eldik, N; van Gemmeren, P; Van Nieuwkoop, J; van Vulpen, I; van Woerden, M C; Vanadia, M; Vandelli, W; Vanguri, R; Vaniachine, A; Vankov, P; Vardanyan, G; Vari, R; Varnes, E W; Varni, C; Varol, T; Varouchas, D; Vartapetian, A; Varvell, K E; Vasquez, J G; Vasquez, G A; Vazeille, F; Vazquez Schroeder, T; Veatch, J; Veeraraghavan, V; Veloce, L M; Veloso, F; Veneziano, S; Ventura, A; Venturi, M; Venturi, N; Venturini, A; Vercesi, V; Verducci, M; Verkerke, W; Vermeulen, J C; Vetterli, M C; Maira, N Viaux; Viazlo, O; Vichou, I; Vickey, T; Boeriu, O E Vickey; Viehhauser, G H A; Viel, S; Vigani, L; Villa, M; Villaplana Perez, M; Vilucchi, E; Vincter, M G; Vinogradov, V B; Vishwakarma, A; Vittori, C; Vivarelli, I; Vlachos, S; Vlasak, M; Vogel, M; Vokac, P; Volpi, G; Volpi, M; von der Schmitt, H; von Toerne, E; Vorobel, V; Vorobev, K; Vos, M; Voss, R; Vossebeld, J H; Vranjes, N; Vranjes Milosavljevic, M; Vrba, V; Vreeswijk, M; Vuillermet, R; Vukotic, I; Wagner, P; Wagner, W; Wahlberg, H; Wahrmund, S; Wakabayashi, J; Walder, J; Walker, R; Walkowiak, W; Wallangen, V; Wang, C; Wang, C; Wang, F; Wang, H; Wang, H; Wang, J; Wang, J; Wang, Q; Wang, R; Wang, S M; 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2017-01-01

Measurements of the electroweak production of a W boson in association with two jets at high dijet invariant mass are performed using [Formula: see text] 7 and 8 [Formula: see text] proton-proton collision data produced by the Large Hadron Collider, corresponding respectively to 4.7 and 20.2 fb[Formula: see text] of integrated luminosity collected by the ATLAS detector. The measurements are sensitive to the production of a W boson via a triple-gauge-boson vertex and include both the fiducial and differential cross sections of the electroweak process.

"kui see päike nyyd niimoodi paistab..." : [luuletused] / [Mesikepp, Indrek] fs

Index Scriptorium Estoniae

fs, pseud., 1971-

2004-01-01

Sisu: "kui see päike nyyd niimoodi paistab..." ; Kodus ; "naha- ja suguhaiguste haigla..." ; "vaipadega kaetud..." ; "need vaiksed eraldatud paigad..." ; "kui ykskord lubatakse väsinud olla..." ; "jaamahoone külmal pingil..."

Process tomography: Seeing is believing

International Nuclear Information System (INIS)

Ondrey, G.; Parkinson, G.

1995-01-01

As the chemical process industries try new ways to optimize their processes, they are taking a closer look at tomography. Already well established in medical diagnostics, the technique has found some CPI applications but has long been considered too expensive and impractical for routine use. Promising to change this perception are recent developments in tomographic sensors, image processing algorithms, as well as data processing. Of particular interest to the CPI is tomography's ability t provide real-time cross sectional images of conditions inside process equipment, allowing operators to see what's going on in such opaque regions as packed catalyst beds, multiphase solutions, powder mixers, and fluidized beds. The images contain a wealth of data that can be used to: design equipment, verify simulation models and calculations derived via computational fluid dynamics, monitor fluid flow and environmental conditions, and image velocity profiles. One interesting application is as a way of inspecting radioactive waste drums to decide where they should be sent for permanent storage. Another use being studied is the monitoring of air sparging of contaminated areas

XbD Video 3, The SEEing process of qualitative data analysis

DEFF Research Database (Denmark)

2013-01-01

This is the third video in the Experience-based Designing series. It presents a live classroom demonstration of a nine step qualitative data analysis process called SEEing: The process is useful for uncovering or discovering deeper layers of 'meaning' and meaning structures in an experience...

The complex association of race and leaving the pediatric emergency department without being seen by a physician.

Science.gov (United States)

Harrison, Blair; Finkelstein, Marsha; Puumala, Susan; Payne, Nathaniel R

2012-11-01

This study examined the influence of race and language on leaving the emergency department (ED) without complete evaluation and treatment (LWCET). This retrospective, case-cohort study examined LWCET among patients discharged home from 2 EDs between March 2, 2009, and March 31, 2010. Race and language were obtained by family self-report. We also explored wait time to see a physician as an explanation of racial disparities. One thousand two hundred eighty-five (1.7%) of 76,931 ED encounters ended in LWCET. Factors increasing LWCET were high ED activity, low acuity, and medical assistance (MA) insurance. American Indian, biracial, African American, and Hispanic races were also associated with higher odds of LWCET among visits by MA insurance patients compared with those of white patients on private insurance. Restricting the analysis to visits by MA insurance patients, only American Indian race was associated with LWCET compared with white race. Visits by patients using an interpreter or speaking a language other than English at home had lower odds of ending in LWCET. Sensitivity analyses in subgroups confirmed these findings. We developed a measure of ED activity that correlated well with wait time to see a physician (correlation coefficient = 0.993; P language, and insurance status interact to form a complex relationship with LWCET. Medical assistance insurance status appears to account for much of the excessive instances of LWCET seen in nonwhites. After restricting the analysis to MA insurance patients, only visits by American Indian patients had higher odds of LWCET compared with whites on MA insurance. Wait time to see a physician did not explain racial differences in LWCET.

Comparison of radiosensitivity of immune cells in three kinds of mice

International Nuclear Information System (INIS)

Wu Hongying; Wang Yueying; Zhang Heng; Li Denguan; Du Liqing; Wang Xiaochun; Lu Lu; Chang Jianhui; Zhang Junling; Zhai Zhibin; Men Aimin

2010-01-01

Objective: To compare the radiosensitivity of thymus (Th), spleen (Sp) cells between IRM-2, ICR and 615 mouse and explore the immunological and radiation resistance mechanisms of IRM-2 mice. Methods: The peripheral blood cytotype was determined by flow cytometry. By PA Law (FITC-Annexin V and PI labeling), the apoptosis of Th and Sp cells was detected after irradiation. Results: CD4/CD8 ratio of IRM-2 mice was lower than that of ICR and 615 mice; CD25/CD4 ratio was higher than 615 mice (P<0.05), lower than ICR mice;apoptosis rate of Sp cells exposed to 0, 1, 4 Gy γ-ray was lower than ICR and 615 mice, the difference was of statistical significance (P<0.05); apoptosis rate of Th cell was lower than ICR and 615 mice, especially 615 mice in 4Gy irradiated group (P<0.01). Conclusion: The apoptosis rate of IRM-2 was lower than that of ICR and 615 mice after irradiation. Th and Sp cells of IRM-2 mice were not sensitive to radiation. (authors)

Information management fiscal year 1996 site support program plan, WBS 6.4. Revision 1

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-09-01

In the recent past, information resource management (IRM) was a neatly separable component of the overall DOE mission, concerned primarily with procuring and implementing automatic data processing (ADP) systems. As the DOE missions have shifted from producing product to managing processes, those clear lines have blurred. Today, IRM is firmly embedded in all aspects of the DOE mission. BCS Richland, Inc., (BCSR) provides IRM for the Hanford Site. The main focus in executing this mission is to meet customer goals by providing high-quality, timely, and cost-effective electronic communication, computing, and information services. Information resources provide the US Department of Energy, Richland Operations Office (RL) and the Hanford Site contractors the ability to generate, store, access, and communicate information quickly, reliably, and cost effectively. BCSR plans, implements, and operates electronic communication, computing and information management systems that enable effective operation of the Hanford Site. Five strategic initiatives to encompass the vision provide guidance and focus to the information technology (IT) direction for developing the BCSR program plan. These strategic initiatives are the program vision and are as follows: primary focus; fast response; accessible information; world class information management infrastructure; powerful desktop. The business directions that guide the development of the BCSR Program Plan are: (1) emphasize providing cost-effective and value-added communication, computing, and information systems products and services to the Site missions; (2) strengthen the alignment of products and services with Site projects and programs and eliminate duplications Sitewide; (3) focus on the effective resolution of critical Site information management (IM) issues.

On static black holes solutions in Einstein and Einstein-Gauss-Bonnet gravity with topology [Formula: see text].

Science.gov (United States)

Dadhich, Naresh; Pons, Josep M

We study static black hole solutions in Einstein and Einstein-Gauss-Bonnet gravity with the topology of the product of two spheres, [Formula: see text], in higher dimensions. There is an unusual new feature of the Gauss-Bonnet black hole: the avoidance of a non-central naked singularity prescribes a mass range for the black hole in terms of [Formula: see text]. For an Einstein-Gauss-Bonnet black hole a limited window of negative values for [Formula: see text] is also permitted. This topology encompasses black strings, branes, and generalized Nariai metrics. We also give new solutions with the product of two spheres of constant curvature.

Impact of visual inspection with acetic acid plus cryotherapy “see ...

African Journals Online (AJOL)

2016-05-18

May 18, 2016 ... Objective: The aim of this study is to determine the impact of visual inspection with acetic acid (VIA) plus immediate .... the “see and treat” model, women who test positive to ... or divorced, and the mean parity was 4.3 ± 1.4.

Seeing in context. Comment on "Seeing mental states: An experimental strategy for measuring the observability of other minds" by Cristina Becchio et al.

Science.gov (United States)

Gallagher, Shaun

2018-03-01

Becchio et al. [1] address questions about direct social perception in the context of interacting with others. In regard to social cognition the claim that we can see mental states is the subject of ongoing debate. Becchio et al. [2,3] have produced some of the best empirical evidence in support of this claim. In explicating and clarifying their methodology Becchio's group is clearly advancing the field and sketching a way to settle the debate.

O cinema brasileiro diante de um presente incendiário: o filme o caso dos irmãos Naves (1967, de Luís Sérgio Person, e o despertar das consciências durante o regime de exceção = Brazilian cinema in face of an incendiary present: the film o caso dos irmãos Naves (1967, by Luís Sérgio Person, and the awakening of consciousness during the dictatorial regime = El cine brasileño frente a un presente incendiario: la película o caso dos irmãos Naves (1967, de Luís Sérgio Person, y el despertar de las conciencias durante el régimen de excepción

Directory of Open Access Journals (Sweden)

Silva, Jaison Castro

2017-01-01

Full Text Available O artigo analisa as diversas opiniões sobre o filme O Caso dos Irmãos Naves (1967, de Luís Sérgio Person, contidas na crítica cinematográfica da época da estreia do filme, que mobilizaram questões humanistas fundamentais, principalmente no que diz respeito à abordagem das violentas cenas de tortura, muitas vezes acusadas de sadismo, existentes naquela película. Em meio à discussão sobre a narrativa cinematográfica e às possibilidades de apagamento do cineasta frente à representação documental da verdade, despontava o debate sobre como as formas imagéticas de produção de sentido podem mobilizar sentimentos e/ou acionar consciências de maneira política. A abordagem histórica, a partir de referências como Walter Benjamin e Giorgio Agamben, insere-se na discussão sobre visualidade, investigando como, apesar de um quadro de referências comum, o período apresentava diferentes formas de acionar as imagens

Search for new phenomena in different-flavour high-mass dilepton final states in pp collisions at [Formula: see text] Tev with the ATLAS detector.

Science.gov (United States)

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Angelidakis, S; Angelozzi, I; Anger, P; Angerami, A; Anghinolfi, F; Anisenkov, A V; Anjos, N; Annovi, A; Antel, C; Antonelli, M; Antonov, A; Anulli, F; Aoki, M; Bella, L Aperio; Arabidze, G; Arai, Y; Araque, J P; Arce, A T H; Arduh, F A; Arguin, J-F; Argyropoulos, S; Arik, M; Armbruster, A J; Armitage, L J; Arnaez, O; Arnold, H; Arratia, M; Arslan, O; Artamonov, A; Artoni, G; Artz, S; Asai, S; Asbah, N; Ashkenazi, A; Åsman, B; Asquith, L; Assamagan, K; Astalos, R; Atkinson, M; Atlay, N B; Augsten, K; Avolio, G; Axen, B; Ayoub, M K; Azuelos, G; Baak, M A; Baas, A E; Baca, M J; Bachacou, H; Bachas, K; Backes, M; Backhaus, M; Bagiacchi, P; Bagnaia, P; Bai, Y; Baines, J T; Baker, O K; Baldin, E M; Balek, P; Balestri, T; Balli, F; Balunas, W K; Banas, E; Banerjee, Sw; Bannoura, A A E; Barak, L; Barberio, E L; Barberis, D; Barbero, M; Barillari, T; Barisits, M-S; Barklow, T; Barlow, N; Barnes, S L; Barnett, B M; Barnett, R M; Barnovska-Blenessy, Z; Baroncelli, A; Barone, G; Barr, A J; Navarro, L Barranco; Barreiro, F; da Costa, J Barreiro Guimarães; Bartoldus, R; Barton, A E; Bartos, P; Basalaev, A; Bassalat, A; Bates, R L; Batista, S J; Batley, J R; Battaglia, M; Bauce, M; Bauer, F; Bawa, H S; Beacham, J B; Beattie, M D; Beau, T; Beauchemin, P H; Bechtle, P; Beck, H P; Becker, K; Becker, M; Beckingham, M; Becot, C; Beddall, A J; Beddall, A; Bednyakov, V A; Bedognetti, M; Bee, C P; Beemster, L J; Beermann, T A; Begel, M; Behr, J K; Belanger-Champagne, C; Bell, A S; Bella, G; Bellagamba, L; Bellerive, A; Bellomo, M; Belotskiy, K; Beltramello, O; Belyaev, N L; Benary, O; Benchekroun, D; Bender, M; Bendtz, K; Benekos, N; Benhammou, Y; Noccioli, E Benhar; Benitez, J; Benjamin, D P; Bensinger, J R; Bentvelsen, S; Beresford, L; Beretta, M; Berge, D; Kuutmann, E Bergeaas; Berger, N; Beringer, J; Berlendis, S; Bernard, N R; Bernius, C; Bernlochner, F U; Berry, T; Berta, P; Bertella, C; Bertoli, G; Bertolucci, F; Bertram, I A; Bertsche, C; Bertsche, D; Besjes, G J; Bylund, O Bessidskaia; Bessner, M; 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Winston, O J; Winter, B T; Wittgen, M; Wittkowski, J; Wolf, T M H; Wolter, M W; Wolters, H; Worm, S D; Wosiek, B K; Wotschack, J; Woudstra, M J; Wozniak, K W; Wu, M; Wu, M; Wu, S L; Wu, X; Wu, Y; Wyatt, T R; Wynne, B M; Xella, S; Xu, D; Xu, L; Yabsley, B; Yacoob, S; Yamaguchi, D; Yamaguchi, Y; Yamamoto, A; Yamamoto, S; Yamanaka, T; Yamauchi, K; Yamazaki, Y; Yan, Z; Yang, H; Yang, H; Yang, Y; Yang, Z; Yao, W-M; Yap, Y C; Yasu, Y; Yatsenko, E; Wong, K H Yau; Ye, J; Ye, S; Yeletskikh, I; Yen, A L; Yildirim, E; Yorita, K; Yoshida, R; Yoshihara, K; Young, C; Young, C J S; Youssef, S; Yu, D R; Yu, J; Yu, J M; Yu, J; Yuan, L; Yuen, S P Y; Yusuff, I; Zabinski, B; Zaidan, R; Zaitsev, A M; Zakharchuk, N; Zalieckas, J; Zaman, A; Zambito, S; Zanello, L; Zanzi, D; Zeitnitz, C; Zeman, M; Zemla, A; Zeng, J C; Zeng, Q; Zengel, K; Zenin, O; Ženiš, T; Zerwas, D; Zhang, D; Zhang, F; Zhang, G; Zhang, H; Zhang, J; Zhang, L; Zhang, R; Zhang, R; Zhang, X; Zhang, Z; Zhao, X; Zhao, Y; Zhao, Z; Zhemchugov, A; Zhong, J; Zhou, B; Zhou, C; Zhou, L; Zhou, L; Zhou, M; Zhou, N; Zhu, C G; Zhu, H; Zhu, J; Zhu, Y; Zhuang, X; Zhukov, K; Zibell, A; Zieminska, D; Zimine, N I; Zimmermann, C; Zimmermann, S; Zinonos, Z; Zinser, M; Ziolkowski, M; Živković, L; Zobernig, G; Zoccoli, A; Nedden, M Zur; Zwalinski, L

2016-01-01

A search is performed for a heavy particle decaying into different flavour dilepton pairs ([Formula: see text], [Formula: see text] or [Formula: see text]), using 3.2 fb[Formula: see text] of proton-proton collision data at [Formula: see text] TeV collected in 2015 by the ATLAS detector at the Large Hadron Collider. No excess over the Standard Model prediction is observed. Limits at the 95 % credibility level are set on the mass of a [Formula: see text] boson with lepton-flavour-violating couplings at 3.0, 2.7 and 2.6 TeV, and on the mass of a supersymmetric [Formula: see text] sneutrino with R -parity-violating couplings at 2.3, 2.2 and 1.9 TeV, for [Formula: see text], [Formula: see text] and [Formula: see text] final states, respectively. The results are also interpreted as limits on the threshold mass for quantum black hole production.

Measurement of ϒ production in pp collisions at [Formula: see text].

Science.gov (United States)

Aaij, R; Abellan Beteta, C; Adeva, B; Adinolfi, M; Adrover, C; Affolder, A; Ajaltouni, Z; Albrecht, J; Alessio, F; Alexander, M; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amhis, Y; Anderson, J; Appleby, R B; Aquines Gutierrez, O; Archilli, F; Arrabito, L; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Bachmann, S; Back, J J; Bailey, D S; Balagura, V; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Bates, A; Bauer, C; Bauer, Th; Bay, A; Bediaga, I; Belogurov, S; Belous, K; Belyaev, I; Ben-Haim, E; Benayoun, M; Bencivenni, G; Benson, S; Benton, J; Bernet, R; Bettler, M-O; van Beuzekom, M; Bien, A; Bifani, S; Bird, T; Bizzeti, A; Bjørnstad, P M; Blake, T; Blanc, F; Blanks, C; Blouw, J; Blusk, S; Bobrov, A; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Bowcock, T J V; Bozzi, C; Brambach, T; van den Brand, J; Bressieux, J; Brett, D; Britsch, M; Britton, T; Brook, N H; Brown, H; de Bruyn, K; Büchler-Germann, A; Burducea, I; Bursche, A; Buytaert, J; 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Huse, T; Huston, R S; Hutchcroft, D; Hynds, D; Iakovenko, V; Ilten, P; Imong, J; Jacobsson, R; Jaeger, A; Jahjah Hussein, M; Jans, E; Jansen, F; Jaton, P; Jean-Marie, B; Jing, F; John, M; Johnson, D; Jones, C R; Jost, B; Kaballo, M; Kandybei, S; Karacson, M; Karbach, T M; Keaveney, J; Kenyon, I R; Kerzel, U; Ketel, T; Keune, A; Khanji, B; Kim, Y M; Knecht, M; Koopman, R F; Koppenburg, P; Korolev, M; Kozlinskiy, A; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kruzelecki, K; Kucharczyk, M; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanciotti, E; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J-P; Lefèvre, R; Leflat, A; Lefrançois, J; Leroy, O; Lesiak, T; Li, L; Li Gioi, L; Lieng, M; Liles, M; Lindner, R; Linn, C; Liu, B; Liu, G; von Loeben, J; Lopes, J H; Lopez Asamar, E; Lopez-March, N; Lu, H; Luisier, J; Mac Raighne, A; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Magnin, J; Malde, S; Mamunur, R M D; Manca, G; Mancinelli, G; Mangiafave, N; Marconi, U; Märki, R; Marks, J; Martellotti, G; Martens, A; Martin, L; Martín Sánchez, A; Martinez Santos, D; Massafferri, A; Mathe, Z; Matteuzzi, C; Matveev, M; Maurice, E; Maynard, B; Mazurov, A; McGregor, G; McNulty, R; Meissner, M; Merk, M; Merkel, J; Messi, R; Miglioranzi, S; Milanes, D A; Minard, M-N; Molina Rodriguez, J; Monteil, S; Moran, D; Morawski, P; Mountain, R; Mous, I; Muheim, F; Müller, K; Muresan, R; Muryn, B; Muster, B; Musy, M; Mylroie-Smith, J; Naik, P; Nakada, T; Nandakumar, R; Nasteva, I; Nedos, M; Needham, M; Neufeld, N; Nguyen, A D; Nguyen-Mau, C; Nicol, M; Niess, V; Nikitin, N; Nomerotski, A; Novoselov, A; Oblakowska-Mucha, A; Obraztsov, V; Oggero, S; Ogilvy, S; Okhrimenko, O; Oldeman, R; Orlandea, M; Otalora Goicochea, J M; Owen, P; Pal, K; Palacios, J; Palano, A; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Parkes, C; Parkinson, C J; Passaleva, G; Patel, G D; Patel, M; Paterson, S K; 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Vazquez Regueiro, P; Vecchi, S; Velthuis, J J; Veltri, M; Viaud, B; Videau, I; Vieira, D; Vilasis-Cardona, X; Visniakov, J; Vollhardt, A; Volyanskyy, D; Voong, D; Vorobyev, A; Voss, H; Wandernoth, S; Wang, J; Ward, D R; Watson, N K; Webber, A D; Websdale, D; Whitehead, M; Wiedner, D; Wiggers, L; Wilkinson, G; Williams, M P; Williams, M; Wilson, F F; Wishahi, J; Witek, M; Witzeling, W; Wotton, S A; Wyllie, K; Xie, Y; Xing, F; Xing, Z; Yang, Z; Young, R; Yushchenko, O; Zangoli, M; Zavertyaev, M; Zhang, F; Zhang, L; Zhang, W C; Zhang, Y; Zhelezov, A; Zhong, L; Zvyagin, A

The production of ϒ (1 S ), ϒ (2 S ) and ϒ (3 S ) mesons in proton-proton collisions at the centre-of-mass energy of [Formula: see text] is studied with the LHCb detector. The analysis is based on a data sample of 25 pb -1 collected at the Large Hadron Collider. The ϒ mesons are reconstructed in the decay mode ϒ → μ + μ - and the signal yields are extracted from a fit to the μ + μ - invariant mass distributions. The differential production cross-sections times dimuon branching fractions are measured as a function of the ϒ transverse momentum p T and rapidity  y , over the range p T <15 GeV/c and 2.0< y <4.5. The cross-sections times branching fractions, integrated over these kinematic ranges, are measured to be [Formula: see text] where the first uncertainty is statistical, the second systematic and the third is due to the unknown polarisation of the three ϒ states.

Validation of the doubly labeled water method using off-axis integrated cavity output spectroscopy and isotope ratio mass spectrometry.

Science.gov (United States)

Melanson, Edward L; Swibas, Tracy; Kohrt, Wendy M; Catenacci, Vicki A; Creasy, Seth A; Plasqui, Guy; Wouters, Loek; Speakman, John R; Berman, Elena S F

2018-02-01

When the doubly labeled water (DLW) method is used to measure total daily energy expenditure (TDEE), isotope measurements are typically performed using isotope ratio mass spectrometry (IRMS). New technologies, such as off-axis integrated cavity output spectroscopy (OA-ICOS) provide comparable isotopic measurements of standard waters and human urine samples, but the accuracy of carbon dioxide production (V̇co 2 ) determined with OA-ICOS has not been demonstrated. We compared simultaneous measurement V̇co 2 obtained using whole-room indirect calorimetry (IC) with DLW-based measurements from IRMS and OA-ICOS. Seventeen subjects (10 female; 22 to 63 yr) were studied for 7 consecutive days in the IC. Subjects consumed a dose of 0.25 g H 2 18 O (98% APE) and 0.14 g 2 H 2 O (99.8% APE) per kilogram of total body water, and urine samples were obtained on days 1 and 8 to measure average daily V̇co 2 using OA-ICOS and IRMS. V̇co 2 was calculated using both the plateau and intercept methods. There were no differences in V̇co 2 measured by OA-ICOS or IRMS compared with IC when the plateau method was used. When the intercept method was used, V̇co 2 using OA-ICOS did not differ from IC, but V̇co 2 measured using IRMS was significantly lower than IC. Accuracy (~1-5%), precision (~8%), intraclass correlation coefficients ( R = 0.87-90), and root mean squared error (30-40 liters/day) of V̇co 2 measured by OA-ICOS and IRMS were similar. Both OA-ICOS and IRMS produced measurements of V̇co 2 with comparable accuracy and precision compared with IC.

Discriminating neutrino mass models using Type-II see-saw formula

Indian Academy of Sciences (India)

though a fuller analysis needs the full matrix form when all terms are present. This is followed by the normal hierarchical model (Type [III]) and inverted hierarchical model with opposite CP phase (Type [IIB]). γ ≃ 10−2 for both of them. Our main results on neutrino masses and mixings in Type-II see-saw formula are presented ...

A New Clinicobiological Scoring System for the Prediction of Infection-Related Mortality and Survival after Allogeneic Hematopoietic Stem Cell Transplantation.

Science.gov (United States)

Forcina, Alessandra; Rancoita, Paola M V; Marcatti, Magda; Greco, Raffaella; Lupo-Stanghellini, Maria Teresa; Carrabba, Matteo; Marasco, Vincenzo; Di Serio, Clelia; Bernardi, Massimo; Peccatori, Jacopo; Corti, Consuelo; Bondanza, Attilio; Ciceri, Fabio

2017-12-01

Infection-related mortality (IRM) is a substantial component of nonrelapse mortality (NRM) after allogeneic hematopoietic stem cell transplantation (allo-HSCT). No scores have been developed to predict IRM before transplantation. Pretransplantation clinical and biochemical data were collected from a study cohort of 607 adult patients undergoing allo-HSCT between January 2009 and February 2017. In a training set of 273 patients, multivariate analysis revealed that age >60 years (P = .003), cytomegalovirus host/donor serostatus different from negative/negative (P < .001), pretransplantation IgA level <1.11 g/L (P = .004), and pretransplantation IgM level <.305 g/L (P = .028) were independent predictors of increased IRM. Based on these results, we developed and subsequently validated a 3-tiered weighted prognostic index for IRM in a retrospective set of patients (n = 219) and a prospective set of patients (n = 115). Patients were assigned to 3 different IRM risk classes based on this index score. The score significantly predicted IRM in the training set, retrospective validation set, and prospective validation set (P < .001, .044, and .011, respectively). In the training set, 100-day IRM was 5% for the low-risk group, 11% for the intermediate-riak group, and 16% for the high-risk groups. In the retrospective validation set, the respective 100-day IRM values were 7%, 17%, and 28%, and in the prospective set, they were 0%, 5%, and 7%. This score predicted also overall survival (P < .001 in the training set, P < 041 in the retrospective validation set, and P < .023 in the prospective validation set). Because pretransplantation levels of IgA/IgM can be modulated by the supplementation of enriched immunoglobulins, these results suggest the possibility of prophylactic interventional studies to improve transplantation outcomes. Copyright © 2017 The American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All

Mixed-mode chromatography/isotope ratio mass spectrometry.

Science.gov (United States)

McCullagh, James S O

2010-03-15

Liquid chromatography coupled to molecular mass spectrometry (LC/MS) has been a standard technique since the early 1970s but liquid chromatography coupled to high-precision isotope ratio mass spectrometry (LC/IRMS) has only been available commercially since 2004. This development has, for the first time, enabled natural abundance and low enrichment delta(13)C measurements to be applied to individual analytes in aqueous mixtures creating new opportunities for IRMS applications, particularly for the isotopic study of biological molecules. A growing number of applications have been published in a range of areas including amino acid metabolism, carbohydrates studies, quantification of cellular and plasma metabolites, dietary tracer and nucleic acid studies. There is strong potential to extend these to new compounds and complex matrices but several challenges face the development of LC/IRMS methods. To achieve accurate isotopic measurements, HPLC separations must provide baseline-resolution between analyte peaks; however, the design of current liquid interfaces places severe restrictions on compatible flow rates and in particular mobile phase compositions. These create a significant challenge on which reports associated with LC/IRMS have not previously focused. Accordingly, this paper will address aspects of chromatography in the context of LC/IRMS, in particular focusing on mixed-mode separations and their benefits in light of these restrictions. It aims to provide an overview of mixed-mode stationary phases and of ways to improve high aqueous separations through manipulation of parameters such as column length, temperature and mobile phase pH. The results of several practical experiments are given using proteogenic amino acids and nucleosides both of which are of noted importance in the LC/IRMS literature. This communication aims to demonstrate that mixed-mode stationary phases provide a flexible approach given the constraints of LC/IRMS interface design and acts as a

Evidence supporting see-and-treat management of cervical intraepithelial neoplasia: a systematic review and meta-analysis.

Science.gov (United States)

Ebisch, R M F; Rovers, M M; Bosgraaf, R P; van der Pluijm-Schouten, H W; Melchers, W J G; van den Akker, P A J; Massuger, L F A G; Bekkers, R L M

2016-01-01

Studies of see-and-treat management of cervical intraepithelial neoplasia (CIN) vary in their inclusion criteria, resulting in a broad range of overtreatment rates. To determine overtreatment rates in see-and-treat management of women referred for colposcopy because of suspected CIN, in order to define circumstances supporting see-and-treat management. MEDLINE, EMBASE, and the Cochrane Library were searched from inception up to 12 May 2014. Studies of see-and-treat management in women with a reported cervical smear result, colposcopic impression, and histology result were included. Methodological quality was assessed with the Newcastle-Ottawa scale. We used the inverse variance method for pooling incidences, and a random-effects model was used to account for heterogeneity between studies. Overtreatment was defined as treatment in patients with no CIN or CIN1. Thirteen studies (n = 4611) were included. The overall overtreatment rate in women with a high-grade cervical smear and a high-grade colposcopic impression was 11.6% (95% CI 7.8-15.3%). The overtreatment rate in women with a high-grade cervical smear and low-grade colposcopic impression was 29.3% (95% CI 16.7-41.9%), and in the case of a low-grade smear and high-grade colposcopic impression it was 46.4% (95% CI 15.7-77.1%). In women with a low-grade smear and low-grade colposcopic impression, the overtreatment rate was 72.9% (95% CI 68.1-77.7%). The pooled overtreatment rate in women with a high-grade smear and high-grade colposcopic impression is at least comparable with the two-step procedure, which supports the use of see-and-treat management in this subgroup of women. See-and-treat management is justified in the case of a high-grade smear and a high-grade colposcopic impression. © 2015 Royal College of Obstetricians and Gynaecologists.

Effects of different 137Cs γ radiation dose on mouse hematopoietic system

International Nuclear Information System (INIS)

Wang Yueying; Wu Hongying; Li Deguan; Wang Xiaochun; Song Naling; Lu Lu; Zhang Junling; Meng Aimin

2013-01-01

Objective: To discuss the effects of different dose of radiation on the mouse's hematopoietic system. Methods: Mice of 615 strain, ICR strain and IRM-2 strain were given a one-time 4.0 Gy total body irradiation,and then the changes of peripheral white blood cells and bone marrow nuclear cells (BMNC) among those mice were observed at different time points. Mice of IRM-2 and C57BL/6 were given a one-time 6.0 Gy total body irradiation and the changes of peripheral hematological between the two strains were observed forty-five days after irradiation. Results: Two days after irradiation,white blood cell and BMNC counts decreased to the lowest level in all the mice of 615 strain, ICR strain and IRM-2 strain. During the following days,white blood cell and BMNC counts raised again. Nine days after irradiation, BMNC count in IRM-2 mice was significantly higher than that in 615 and ICR mice (t=3.725, P<0.01; t=8.487, P<0.001). Twelve days after irradiation,white blood cell count in IRM-2 mice was significantly higher than that in the 615 and ICR mice (t=4.811 and 4.302, both P <0.001). Twenty-one days after irradiation,compared to the control group,white blood cell count was recovered to 52.0%, 60.7% and 50.8% of the normal range in IRM-2, ICR and 615 mice separately and BMNC count was recovered to 90.8%, 82.1%, 75.4% of the normal range in IRM-2, ICR and 615 mice separately. Forty-five days after 6.0 Gy irradiation,white blood cell, BMNC, hemoglobin and hematocrit counts in IRM-2 mice were significantly higher than those indexes in C57BL/6 strain (t=5.629, 7.788, 4.9289, 6.064, all P<0.001). Compared to the control group, white blood cells, red blood cells,hemoglobin and hematocrit were recovered to 75.0%, 98.9%, 98.7%, and 97.5% of the normal range separately in IRM-2 mice. And white blood cells, red blood cells,hemoglobin and hematocrit were recovered to 40.6%, 93.8%, 93.3%, and 93.8% of the normal range separately in C57BL/6 mice. Conclusion: There are similar

Application of the Infinite Relational Model combined with the Bayesian Model of Generalization for Effective Cross-Cultural Knowledge Transfer

DEFF Research Database (Denmark)

Glückstad, Fumiko Kano; Mørup, Morten

2012-01-01

at hand, thereafter to apply the IRM for clustering CSCs in the respective cultures into categorical classes. The results indicate that the third strategy seems to be the most effective approach for not only clustering CSCs into more specific and appropriate categorical classes but also for capturing......This paper investigates how the Infinite Relational Model (IRM) [Kemp 2006], a novel unsupervised machine learning method, is effectively applied to loosely-structured datasets consisting of concepts and features for the purpose of mapping Culturally Specific Concepts (CSCs) in a multi-cultural...... context. The aim of this investigation is two-fold: i) to identify an effective strategy of applying the IRM for the purpose of CSC-mapping; and ii) to investigate possibilities of applying the IRM for efficiently constructing feature-based ontologies that are multi-culturally interoperable. Accordingly...

Contrasting Roles of Islet Resident Immunoregulatory Macrophages and Dendritic Cells in Experimental Autoimmune Type 1 Diabetes

Science.gov (United States)

Thornley, Thomas B.; Ma, Lingzhi; Chipashvili, Vaja; Aker, Jonathan E.; Korniotis, Sarantis; Csizmadia, Eva; Strom, Terry B.; Koulmanda, Maria

2016-01-01

The innate immune system critically shapes diabetogenic adaptive immunity during type 1 diabetes (T1D) pathogenesis. While the role of tissue-infiltrating monocyte-derived macrophages in T1D is well established, the role of their tissue-resident counterparts remains undefined. We now demonstrate that islet resident macrophages (IRMs) from non-autoimmune mice have an immunoregulatory phenotype and powerfully induce FoxP3+ Tregs in vitro. The immunoregulatory phenotype and function of IRMs is compromised by TLR4 activation in vitro. Moreover, as T1D approaches in NOD mice, the immunoregulatory phenotype of IRMs is diminished as is their relative abundance compared to immunostimulatory DCs. Our findings suggest that maintenance of IRM abundance and their immunoregulatory phenotype may constitute a novel therapeutic strategy to prevent and/or cure T1D. PMID:26943809

SEE: improving nurse-patient communications and preventing software piracy in nurse call applications.

Science.gov (United States)

Unluturk, Mehmet S

2012-06-01

Nurse call system is an electrically functioning system by which patients can call upon from a bedside station or from a duty station. An intermittent tone shall be heard and a corridor lamp located outside the room starts blinking with a slow or a faster rate depending on the call origination. It is essential to alert nurses on time so that they can offer care and comfort without any delay. There are currently many devices available for a nurse call system to improve communication between nurses and patients such as pagers, RFID (radio frequency identification) badges, wireless phones and so on. To integrate all these devices into an existing nurse call system and make they communicate with each other, we propose software client applications called bridges in this paper. We also propose a window server application called SEE (Supervised Event Executive) that delivers messages among these devices. A single hardware dongle is utilized for authentication and copy protection for SEE. Protecting SEE with securities provided by dongle only is a weak defense against hackers. In this paper, we develop some defense patterns for hackers such as calculating checksums in runtime, making calls to dongle from multiple places in code and handling errors properly by logging them into database.

Borboletas frugívoras (Lepidoptera: Nymphalidae no Horto Botânico Irmão Teodoro Luis, Capão do Leão, Rio Grande do Sul, Brasil

Directory of Open Access Journals (Sweden)

Janaína Madruga Silva

2012-12-01

Full Text Available http://dx.doi.org/10.5007/2175-7925.2013v26n1p87 No Rio Grande do Sul, há carência de informações sistematizadas sobre a fauna de borboletas frugívoras. Este artigo teve por objetivo inventariar a guilda no Horto Botânico Irmão Teodoro Luis, ambiente caracterizado pela tensão ecológica entre a floresta estacional semidecidual e as formações pioneiras. As coletas foram realizadas em três áreas, cada uma contendo cinco armadilhas Van Someren-Rydon modificadas, iscadas com banana fermentada. As armadilhas permaneceram em campo durante seis dias consecutivos por mês, entre setembro de 2010 e agosto de 2011. Em 10.800 horas de esforço amostral, foram registrados 453 indivíduos distribuídos em 16 espécies, 15 gêneros e três subfamílias de Nymphalidae. Satyrinae foi a mais rica e abundante, sendo duas espécies deste grupo muito frequentes e dominantes. Os índices de riqueza indicaram entre 78% e 93% da fauna registrada, a curva de acúmulo de espécies condiz com esses valores e a diversidade foi de 2,02 (H’. Prepona pylene Hewitson, [1854] e Archaeoprepona demophoon (Hübner, [1814] constituem novos registros para o Litoral Sul do estado.

"Mãe, quero ficar contigo...": comportamentos de dependência do primogênito no contexto de gestação de um irmão "Mum, I want to stay with you...": firstborn's dependence behaviours in the context of a sibling's gestation

Directory of Open Access Journals (Sweden)

Débora Silva de Oliveira

2008-01-01

Full Text Available O estudo investigou os comportamentos de dependência do primogênito no contexto de gestação de um segundo filho. Participaram cinco primogênitos em idade pré-escolar e suas respectivas mães, no terceiro trimestre de gestação. Foi aplicado Teste das Fábulas nas crianças e realizadas entrevistas semi-dirigidas com as mães. Os resultados revelaram tendência de comportamento de dependência do primogênito. Observaram-se também comportamentos de independência, indicando ambivalência. Os resultados sugerem que a gestação do irmão constitui-se momento especial para a criança que tem que deixar de ser filho único e aprender a compartilhar os cuidados maternos. A investigação acerca das mudanças nas relações familiares e suas implicações para cada um dos membros são de fundamental importância para a compreensão do desenvolvimento humano. Este artigo contribui para a literatura existente que não tem contemplado especificamente em que medida o comportamento do primogênito é afetado pela existência de um irmão durante a gestação.The study investigated the firstborn's dependence behaviors in the context of a second child's pregnancy. Five preschool firstborns and their respective mothers, in the third trimester of pregnancy, took part in the study. The Fables Test was used in order to assess children's perceptions, and a semi-structured interview in order to investigate mothers' perceptions. The results revealed a dependence behavior tendency in the firstborn. There were also independence behaviors suggesting ambivalence. The results indicate that a second child's pregnancy is a special moment for the firstborn who is no longer an only child and has to learn to share maternal care. The investigation concerning changes in family relationships and their implications for each family member are of fundamental importance for understanding human development. This article represents a contribution to the literature which has

Seeing Iconic Gestures While Encoding Events Facilitates Children's Memory of These Events.

Science.gov (United States)

Aussems, Suzanne; Kita, Sotaro

2017-11-08

An experiment with 72 three-year-olds investigated whether encoding events while seeing iconic gestures boosts children's memory representation of these events. The events, shown in videos of actors moving in an unusual manner, were presented with either iconic gestures depicting how the actors performed these actions, interactive gestures, or no gesture. In a recognition memory task, children in the iconic gesture condition remembered actors and actions better than children in the control conditions. Iconic gestures were categorized based on how much of the actors was represented by the hands (feet, legs, or body). Only iconic hand-as-body gestures boosted actor memory. Thus, seeing iconic gestures while encoding events facilitates children's memory of those aspects of events that are schematically highlighted by gesture. © 2017 The Authors. Child Development © 2017 Society for Research in Child Development, Inc.

Department

African Journals Online (AJOL)

USER

2016-09-20

Sep 20, 2016 ... Department of Biological and Environmental Sciences, Kibabii University. Abstract. This study ... Key Words: Climate Change, Regional Circulation Model, PRECIS, Bungoma County ... by different computer models is much.

Response Variability in Commercial MOSFET SEE Qualification

International Nuclear Information System (INIS)

George, J. S.; Clymer, D. A.; Turflinger, T. L.; Mason, L. W.; Stone, S.

2016-01-01

Single-event effects (SEE) evaluation of five different part types of next generation, commercial trench MOSFETs indicates large part-to-part variation in determining a safe operating area (SOA) for drain-source voltage (V_D_S) following a test campaign that exposed >50 samples per part type to heavy ions. These results suggest a determination of a SOA using small sample sizes may fail to capture the full extent of the part-to-part variability. An example method is discussed for establishing a Safe Operating Area using a one-sided statistical tolerance limit based on the number of test samples. Finally, burn-in is shown to be a critical factor in reducing part-to-part variation in part response. Implications for radiation qualification requirements are also explored.

The association between individual counselling and health behaviour change: the See Kidney Disease (SeeKD) targeted screening programme for chronic kidney disease.

Science.gov (United States)

Galbraith, Lauren; Hemmelgarn, Brenda; Manns, Braden; Samuel, Susan; Kappel, Joanne; Valk, Nadine; Ronksley, Paul

2016-01-01

Health behaviour change is an important component of management for patients with chronic kidney disease (CKD); however, the optimal method to promote health behaviour change for self-management of CKD is unknown. The See Kidney Disease (SeeKD) targeted screening programme screened Canadians at risk for CKD and promoted health behaviour change through individual counselling and goal setting. The objectives of this study are to determine the effectiveness of individual counselling sessions for eliciting behaviour change and to describe participant characteristics associated with behaviour change. This is a cross-sectional, descriptive study. The study setting is the National SeeKD targeted screening programme. The participants are all 'at risk' patients who were screened for CKD and returned a follow-up health behaviour survey (n = 1129). Health behaviour change was defined as a self-reported change in lifestyle, including dietary changes or medication adherence. An individual counselling session was provided to participants by allied healthcare professionals to promote health behaviour change. A survey was mailed to all participants at risk of CKD within 2-4 weeks following the screening event to determine if behaviour changes had been initiated. Descriptive statistics were used to describe respondent characteristics and self-reported behaviour change following screening events. Results were stratified by estimated glomerular filtration rate (eGFR) (change. Of the 1129 respondents, the majority (89.8 %) reported making a health behaviour change after the screening event. Respondents who were overweight (body mass index [BMI] 25-29.9 kg/m(2)) or obese (BMI ≥ 30.0 kg/m(2)) were more likely to report a behaviour change (prevalence rate ratio (PRR) 0.66, 95 % confidence interval (CI) 0.44-0.99 and PRR 0.49, 95 % CI 0.30-0.80, respectively). Further, participants with a prior intent to change their behaviour were more likely to make a behaviour change

SEE in-flight measurement on the MIR orbital station

International Nuclear Information System (INIS)

Falguere, D.; Duzellier, S.; Ecoffet, R.

1994-01-01

SEE spaceflight measurements are presented on HM65756 SRAM from Matra-MHS, Seeq 28C256 and Motorola MC68020 microprocessor (bulk version) in the MIR station orbit (350 km altitude, 51.6 degree inclination). Accelerator testing (heavy ion and proton) of flight spares permits the prediction of the event rates using standard model such as CREME and SPACERAD as well as characterizations of the flight components allowing the comparison of in-orbit observations. Event rate prediction and ground-testing data are compared

Remanence properties of Co-precipitated cobalt ferrite

International Nuclear Information System (INIS)

Bueno-Baques, D.; Medina-Boudri, Angela; Matutes-Aquino, J.

2001-01-01

Isothermal remanent magnetization (IRM) and DC demagnetization (DCD) curves of a co-precipitated cobalt ferrite sample were obtained. From the IRM and DCD data, the Henkel plot was obtained and analyzed in the Preisach model framework. The Henkel plot data are below the Wohlfarth line that indicates a dominant local disorder (demagnetizing-like effect). Forward and reverse switching field distribution curves were obtained from differentiation of the IRM and DCD curves. The peak values of these switching field distributions differ by a factor of about 2.7

Recruitment of occipital cortex during sensory substitution training linked to subjective experience of seeing in people with blindness.

Directory of Open Access Journals (Sweden)

Tomás Ortiz

Full Text Available Over three months of intensive training with a tactile stimulation device, 18 blind and 10 blindfolded seeing subjects improved in their ability to identify geometric figures by touch. Seven blind subjects spontaneously reported 'visual qualia', the subjective sensation of seeing flashes of light congruent with tactile stimuli. In the latter subjects tactile stimulation evoked activation of occipital cortex on electroencephalography (EEG. None of the blind subjects who failed to experience visual qualia, despite identical tactile stimulation training, showed EEG recruitment of occipital cortex. None of the blindfolded seeing humans reported visual-like sensations during tactile stimulation. These findings support the notion that the conscious experience of seeing is linked to the activation of occipital brain regions in people with blindness. Moreover, the findings indicate that provision of visual information can be achieved through non-visual sensory modalities which may help to minimize the disability of blind individuals, affording them some degree of object recognition and navigation aid.

Recruitment of occipital cortex during sensory substitution training linked to subjective experience of seeing in people with blindness.

Science.gov (United States)

Ortiz, Tomás; Poch, Joaquín; Santos, Juan M; Requena, Carmen; Martínez, Ana M; Ortiz-Terán, Laura; Turrero, Agustín; Barcia, Juan; Nogales, Ramón; Calvo, Agustín; Martínez, José M; Córdoba, José L; Pascual-Leone, Alvaro

2011-01-01

Over three months of intensive training with a tactile stimulation device, 18 blind and 10 blindfolded seeing subjects improved in their ability to identify geometric figures by touch. Seven blind subjects spontaneously reported 'visual qualia', the subjective sensation of seeing flashes of light congruent with tactile stimuli. In the latter subjects tactile stimulation evoked activation of occipital cortex on electroencephalography (EEG). None of the blind subjects who failed to experience visual qualia, despite identical tactile stimulation training, showed EEG recruitment of occipital cortex. None of the blindfolded seeing humans reported visual-like sensations during tactile stimulation. These findings support the notion that the conscious experience of seeing is linked to the activation of occipital brain regions in people with blindness. Moreover, the findings indicate that provision of visual information can be achieved through non-visual sensory modalities which may help to minimize the disability of blind individuals, affording them some degree of object recognition and navigation aid.

Online gas chromatography combustion/pyrolysis-isotope ratio mass spectrometry (HRGC-C/P-IRMS) of (+/-)-Dihydroactinidiolide from tea ( Camellia sinensis ) and rooibos tea ( Aspalathus linearis ).

Science.gov (United States)

del Mar Caja, María; Preston, Christina; Menzel, Michael; Kempf, Michael; Schreier, Peter

2009-07-08

Online capillary gas chromatography-isotope ratio mass spectrometry in both the combustion and the pyrolysis modes (HRGC-C/P-IRMS) was employed to perform authentication studies of the flavoring agent (+/-)-dihydroactinidiolide. Thus, the delta(13)C(V-PDB) and delta(2)H(V-SMOW) values of synthetic (ex synthetic beta-ionone and natural beta-carotene) as well as enzymatically (ex synthetic and natural beta-carotene) produced references were studied in comparison with those of the natural substance isolated from black (n = 17) and green teas (n = 6) ( Camellia sinensis ) as well as Rooibos tea ( Aspalathus linearis ) (n = 7). The isotope values determined for both the synthetic and enzymatically produced samples of (+/-)-dihydroactinidiolide reflected the influence of the origin of their educts. Hence, in cases when synthetic educts were used, the delta(13)C(V-PDB) and delta(2)H(V-SMOW) values ranged from -27.0 to -28.4 per thousand and from -28 to -169 per thousand, respectively, whereas the use of natural educts led to ranges from -30.3 to -31.6 per thousand and from -154 to -228 per thousand, respectively. As to the tea samples, delta(13)C(V-PDB) and delta(2)H(V-SMOW) values ranging from -29.0 to -34.1 per thousand and from -153 to -274 per thousand, respectively, were recorded for (+/-)-dihydroactinidiolide from black and green teas, whereas that from Rooibos tea showed (2)H/(1)H ratios ranging from -189 to -210 per thousand as well as slightly enriched values in the (13)C/(12)C ratios ranging from -24.4 to -27.1 per thousand.

Dispersão de diásporos e ecologia morfofuncional de plântulas de espécies de um fragmento de Floresta Atlântica em Dois Irmãos, Recife–PE. Propagule dispersion and morphofunctional seedling ecology of species in an Atlantic Forest fragment in Dois Irmãos, Recife–PE

Directory of Open Access Journals (Sweden)

Diogenes José Gusmão COUTINHO

2012-06-01

Full Text Available Trabalhos sobre dispersão de frutos e sementes e aspectos morfofuncionais de plântulas podem fornecer informações essenciais no esclarecimento de questões ligadas à sucessão ecológica, além de contribuir nos trabalhos de inventário, conservação e regeneração de ecossistemas naturais, uma vez que contribuem para a compreensão das funções das estruturas morfológicas nos processos de desenvolvimento e estabelecimento das plantas. Diante do exposto, a presente investigação objetivou levantar as síndromes de dispersão e a morfofuncionalidade de plântulas de espécies de fanerógamos de um fragmento de Floresta Atlântica em Dois Irmãos, Recife–PE. O levantamento das espécies e coleta de material fértil foi feito pelo método do caminhamento, entre o período de janeiro de 2008 e agosto de 2011. As espécies foram demarcadas com fitas e acompanhadas quanto à produção de frutos e sementes para determinação da síndrome de dispersão e posterior germinação, visando à obtenção das plântulas. Também foram feitas observações de campo para identificação das sementes germinadas e plântulas encontradas na serrapilheira. A caracterização da síndrome de dispersão e morfofuncionalidade de plântulas foram feitas através de observações em campo e literatura. Foram levantadas 85 espécies, distribuídas em 19 famílias e 60 gêneros. Quanto ao hábito, 63,85% das espécies são árvores, 16,86% são arbustos, 14,45% são trepadeiras e 7,22% são ervas. A síndrome de dispersão mais frequente foi a zoocoria (66,66%, seguida da autocoria (18,84% e anemocoria (13,05%. O padrão de morfofuncionalidade de plântulas predominantes foi o fanerocotiledonar-epígeo com cotilédones do tipo foliáceo, semelhante ao padrão descrito na literatura para as florestas tropicais úmidas não inundáveis. Papers on fruit and seed dispersal and seedling morphofunctional aspects can provide essential information to clarify issues

31 CFR 19.430 - How do I check to see if a person is excluded or disqualified?

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false How do I check to see if a person is excluded or disqualified? 19.430 Section 19.430 Money and Finance: Treasury Office of the Secretary of the... disqualified? You check to see if a person is excluded or disqualified in two ways: (a) You as an agency...

Measurement of DNA breakage and breakage repair in mice spleen cells induced by ionizing radiation

International Nuclear Information System (INIS)

Wang Qin; Xue Jingying; Li Jin; Mu Chuanjie; Fan Feiyue

2007-01-01

Objective: To investigate the radioresistance mechanism of IBM-2 mice through measuring DNA single-strand break(SSB) and double-strands break (DSB) as well as their repair. Methods: Pulsed-field gel electrophoresis was used to measure DSB and SSB in IRM-2 mice and their parental mice ICR/JCL and 615 mice after exposure to different doses of γ-ray at different postirradiation time. Results: The initial DNA damages, ie the quantities of DSB and SSB in unirradiation IRM-2 mice were less serious than that of their parental mice ICR/JCL and 615 alice(P<0.01). The percent- age of DSB and SSB in IBM -2 mice was significantly lower than that of ICB/JCL and 615 mice after exposure to various doses of γ-ray(P<0.01 and P<0.05). There were not statistic differences in DSB and SSB repair between IRM-2 mice and their parental mice after exposure to 2Gy radiation. The DNA damage repair rate induced by 4Gy and 8Gy radiation in IRM - 2 mice was rapid, ie the repair rate of SSB and DSB after 0.5h and 1h postirradiation in IRM-2 mice was higher than that of their' parental mice (P<0.01 and P<0.05). And remaining damages after repair in IRM-2 mice were lower than that of ICR/JCL and 615 mice. Conclusion: The DNA damages in IBM-2 mice were lower than that of their parental mice after exposure to ionizing radiation. Moreover, the repair rate of SSB and DSB was higher than that of their parental mice, which perhaps were the radioresistance causes of IBM-2 mice. Therefore IRM-2 mice are naturally resistant to DNA damages induced by ionizing radiation. (authors)

Measurement of Muscle Protein Fractional Synthetic Rate by Capillary Gas Chromatography/Combustion Isotope Ratio Mass Spectrometry

Science.gov (United States)

Yarasheski, Kevin E.; Smith, Kenneth; Rennie, Michael J.; Bier, Dennis M.

2014-01-01

The measurement of skeletal muscle protein fractional synthetic rate using an infusion of (1-13C)leucine and measuring the isotopic abundance of the tracer in skeletal muscle protein by preparative gas chromatography (GC)/ninhydrin isotope ratio mass spectrometry (IRMS) is laborious and subject to errors owing to contamination by 12C. The purpose of this study was to compare muscle (13C)leucine enrichment measured with the conventional preparative GC/ninhydrin IRMS approach to a new, continuous-flow technique using capillary GC/combustion IRMS. Quadriceps muscles were removed from four Sprague–Dawley rats after each was infused at a different rate with (1-13C)leucine for 6–8 h. Muscle leucine enrichment (at.% excess) measured by both methods differed by less than 4%, except at low (13C)leucine enrichments (IRMS was used to assess muscle (13C)leucine enrichment and fractional muscle protein synthesis rate in ten normal young men and women infused with (1,2-13C2)leucine for 12–14 h. This approach reduced the variability of the isotope abundance measure and gave estimates of muscle protein synthesis rate (0.050 ± 0.011% h−1 (mean ± SEM); range = 0.023–0.147% h−1) that agree with published values determined using the standard analytical approach. The measurement of (13C)leucine enrichment from skeletal muscle protein by capillary GC/combustion IRMS provides a simple, acceptable and practical alternative to preparative GC/ninhydrin IRMS. PMID:1420371

The mRNA expression of XRCC repair genes in mice after γ-ray radiation

International Nuclear Information System (INIS)

Wang Qin; Yue Jingyin; Li Jin; Mu Chuanjie; Fan Feiyue

2006-01-01

Objective: To investigate the role of XRCC repair genes in radioresistance of IRM-2 inbred mice. Methods: Northern hybridization was used to measure mRNA expression of XRCC1 and XRCC5 genes in IRM-2 inbred mice. ICR/JCL and 615 after exposure to different doses of γ-ray radiation at different postirradiation time. Results: The levels of XRCC1 and XRCC5 mRNA expression in control IRM-2 mice were higher significantly than those in their control parental mice (P<0.01 and P<0.05). The mRNA expression of XRCC genes in ICR/JCL and 615 mice all increased to some extent after exposure 1, 2 and 4 Gy radiation. But the levels were significantly higher at 2h postirradiation (P<0.05) . The levels of XRCC mRNA expression in IRM-2 mice did not increase significnatly compared with the control mice after exposure 1 and 2 Gy radiation. But the levels of XRCC1 and XRCC5 mRNA expression increased markedly at 4Gy 1h postirradiation (P<0.05 and P<0.01). Conclusion: The basal levels of XRCC1 and XRCC5 mRNA expression in IRM-2 mice were high. The high level of XRCC5 mRNA expression was involved in the repair of DNA double strand breaks induced by higher dose radiation, which perhaps was one of radioresistance causes of IRM-2 mice. (authors)

An Implentation Methodology for Integrated Resource Management in Urban Water Planning

Science.gov (United States)

Ebrahimi, G.; Thurm, B.; Klein, D. R.; Öberg, G.

2014-12-01

Urban water management requires innovative and integrative approaches to improve sustainability in cities keeping in touch with science progress. Integrated Resource Management (IRM) is one of these strategies and has been developed to integrate various natural and human resources. However, it is becoming increasingly clear that it is challenging to move from vision to implementation. The aim of this paper is to identify strengths and weaknesses of IRM and analyze if the approach might facilitate implementation of sustainability objectives in the water management field. A literature review was performed on peer-reviewed papers that were identified through Google Scholar search for the term 'Integrated Resource Management'. It was found that IRM has been used in a number of contexts such as urban planning, forestry, and management of waste and livestock. Significant implementation challenges are highlighted in the literature. Based on the lessons learned in many different fields, from forestry to communication sciences, important characteristics of IRM approach were found such as the need for adequate governance and strong leaderships, stakeholder's involvement, the learning process and the critical need of appropriate evaluation criteria. We conclude developing an implementation methodology and presenting several recommendations to implement IRM in urban management. While Integrated Water Resource Management (IWRM) is recognized as a fruitful approach to achieve sustainable water management, this study suggests that a shift toward Integrated Resource Management (IRM) can be beneficial as it is designed to facilitate consideration of the interrelationships between various natural and human resources.

Spatially resolved δ13C analysis using laser ablation isotope ratio mass spectrometry

Science.gov (United States)

Moran, J.; Riha, K. M.; Nims, M. K.; Linley, T. J.; Hess, N. J.; Nico, P. S.

2014-12-01

Inherent geochemical, organic matter, and microbial heterogeneity over small spatial scales can complicate studies of carbon dynamics through soils. Stable isotope analysis has a strong history of helping track substrate turnover, delineate rhizosphere activity zones, and identifying transitions in vegetation cover, but most traditional isotope approaches are limited in spatial resolution by a combination of physical separation techniques (manual dissection) and IRMS instrument sensitivity. We coupled laser ablation sampling with isotope measurement via IRMS to enable spatially resolved analysis over solid surfaces. Once a targeted sample region is ablated the resulting particulates are entrained in a helium carrier gas and passed through a combustion reactor where carbon is converted to CO2. Cyrotrapping of the resulting CO2 enables a reduction in carrier gas flow which improves overall measurement sensitivity versus traditional, high flow sample introduction. Currently we are performing sample analysis at 50 μm resolution, require 65 ng C per analysis, and achieve measurement precision consistent with other continuous flow techniques. We will discuss applications of the laser ablation IRMS (LA-IRMS) system to microbial communities and fish ecology studies to demonstrate the merits of this technique and how similar analytical approaches can be transitioned to soil systems. Preliminary efforts at analyzing soil samples will be used to highlight strengths and limitations of the LA-IRMS approach, paying particular attention to sample preparation requirements, spatial resolution, sample analysis time, and the types of questions most conducive to analysis via LA-IRMS.

Measurement of the top-quark mass in the fully hadronic decay channel from ATLAS data at [Formula: see text].

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Aad, G; Abbott, B; Abdallah, J; Abdel Khalek, S; Abdinov, O; Aben, R; Abi, B; Abolins, M; AbouZeid, O S; Abramowicz, H; Abreu, H; Abreu, R; Abulaiti, Y; Acharya, B S; Adamczyk, L; Adams, D L; Adelman, J; Adomeit, S; Adye, T; Agatonovic-Jovin, T; Aguilar-Saavedra, J A; Agustoni, M; Ahlen, S P; Ahmadov, F; Aielli, G; Akerstedt, H; Åkesson, T P A; Akimoto, G; Akimov, A V; Alberghi, G L; Albert, J; Albrand, S; Alconada Verzini, M J; Aleksa, M; Aleksandrov, I N; Alexa, C; Alexander, G; Alexandre, G; Alexopoulos, T; Alhroob, M; Alimonti, G; Alio, L; Alison, J; Allbrooke, B M M; Allison, L J; Allport, P P; Almond, J; Aloisio, A; Alonso, A; Alonso, F; Alpigiani, C; Altheimer, A; Alvarez Gonzalez, B; Alviggi, M G; Amako, K; Amaral Coutinho, Y; Amelung, C; Amidei, D; Amor Dos Santos, S P; Amorim, A; Amoroso, S; Amram, N; Amundsen, G; Anastopoulos, C; Ancu, L S; Andari, N; Andeen, T; Anders, C F; Anders, G; Anderson, K J; Andreazza, A; Andrei, V; Anduaga, X S; Angelidakis, S; Angelozzi, I; Anger, P; 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Thompson, A S; Thomsen, L A; Thomson, E; Thomson, M; Thong, W M; Thun, R P; Tian, F; Tibbetts, M J; Tikhomirov, V O; Tikhonov, Yu A; Timoshenko, S; Tiouchichine, E; Tipton, P; Tisserant, S; Todorov, T; Todorova-Nova, S; Toggerson, B; Tojo, J; Tokár, S; Tokushuku, K; Tollefson, K; Tomlinson, L; Tomoto, M; Tompkins, L; Toms, K; Topilin, N D; Torrence, E; Torres, H; Torró Pastor, E; Toth, J; Touchard, F; Tovey, D R; Tran, H L; Trefzger, T; Tremblet, L; Tricoli, A; Trigger, I M; Trincaz-Duvoid, S; Tripiana, M F; Trischuk, W; Trocmé, B; Troncon, C; Trottier-McDonald, M; Trovatelli, M; True, P; Trzebinski, M; Trzupek, A; Tsarouchas, C; Tseng, J C-L; Tsiareshka, P V; Tsionou, D; Tsipolitis, G; Tsirintanis, N; Tsiskaridze, S; Tsiskaridze, V; Tskhadadze, E G; Tsukerman, I I; Tsulaia, V; Tsuno, S; Tsybychev, D; Tudorache, A; Tudorache, V; Tuna, A N; Tupputi, S A; Turchikhin, S; Turecek, D; Turk Cakir, I; Turra, R; Tuts, P M; Tykhonov, A; Tylmad, M; Tyndel, M; Uchida, K; Ueda, I; Ueno, R; Ughetto, M; 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The mass of the top quark is measured in a data set corresponding to 4.6 [Formula: see text] of proton-proton collisions with centre-of-mass energy [Formula: see text] TeV collected by the ATLAS detector at the LHC. Events consistent with hadronic decays of top-antitop quark pairs with at least six jets in the final state are selected. The substantial background from multijet production is modelled with data-driven methods that utilise the number of identified [Formula: see text]-quark jets and the transverse momentum of the sixth leading jet, which have minimal correlation. The top-quark mass is obtained from template fits to the ratio of three-jet to dijet mass. The three-jet mass is calculated from the three jets produced in a top-quark decay. Using these three jets the dijet mass is obtained from the two jets produced in the [Formula: see text] boson decay. The top-quark mass obtained from this fit is thus less sensitive to the uncertainty in the energy measurement of the jets. A binned likelihood fit yields a top-quark mass of [Formula: see text].

Recurrent pregnancy failure is associated with a polymorphism in the p53 tumour suppressor gene.

Science.gov (United States)

Pietrowski, Detlef; Bettendorf, Hertha; Riener, Eva-Katrin; Keck, Christoph; Hefler, Lukas A; Huber, Johannes C; Tempfer, Clemens

2005-04-01

The p53 tumour suppressor gene is a well-known factor regulating apoptosis in a wide variety of cells and tissues. Alterations in the p53 gene are among the most common genetic changes in human cancers. In addition, recent data provide evidence that p53 plays a critical role in mediating pregnancy by regulating steroid hormone activation. In idiopathic recurrent miscarriages (IRM), causes and associations are much debated as the exact pathophysiological mechanisms are unknown. In this study, we assess whether an established polymorphism in the p53 gene is associated with the occurrence of IRM. Genotyping was performed by PCR-based amplification of the p53 Arg and Pro variants at codon 72 in 175 cases of IRM and 143 controls. We observed a statistically significant association between carriage of the Pro allele and the occurrence of IRM (P = 0.03, odds ratio 1.49, confidence interval 1.04-2.14). Distribution of genotypes was in Hardy-Weinberg equilibrium. Our results indicate an over-representation of the Pro allele of the p53 gene in women with IRM, giving support to the theory that p53 has a potential role during pregnancy.

Modelling of isothermal remanence magnetisation curves for an assembly of macrospins

International Nuclear Information System (INIS)

Tournus, F.

2015-01-01

We present a robust and efficient framework to compute isothermal remanent magnetisation (IRM) curves for magnetic nanoparticle assemblies. The assembly is modelled by independent, randomly oriented, uniaxial macrospins and we use a Néel model to take into account the thermal relaxation. A simple analytic expression is established for a single size, in a sudden switching approximation, and is compared to more evolved models. We show that for realistic samples (necessarily presenting a size dispersion) the simple model is very satisfactory. With this framework, it is then possible to reliably simulate IRM curves, which can be compared to experimental measurements and used in a best fit procedure. We also examine the influence of several parameters on the IRM curves and we discuss the link between the irreversible susceptibility and the switching field distribution. - Highlights: • A framework to compute IRM curves for nanoparticle assemblies is presented. • A simple analytic expression (for a single size) is compared to more evolved models. • The simple expression can reliably simulate IRM curves for realistic samples. • Irreversible susceptibility and the influence of several parameters is discussed

Expressed sequence tags of differential genes in the radioresistant mice and their parental mice

International Nuclear Information System (INIS)

Wang Qin; Yue Jingyin; Li Jin; Song Li; Liu Qiang; Mu Chuanjie; Wu Hongying

2009-01-01

Objective: To explore radioresistance correlative genes in IRM-2 inbred mouse. Methods: The total RNA was extracted from spleen cells of IRM-2 and their parent 615 and ICR/JCL mouse. The mRNA differential display technique was used to analyze gene expression differences. Each differential bands were amplified by PCR, cloned and sequenced. Results: There were 75 differential expression bands appearing in IRM-2 mouse but not in 615 and ICR/JCL mouse. Fifty-two pieces of cDNA sequences were got by sequencing. Twenty-one expressed sequence tags (EST) that were not the same as known mice genes were found and registered by comparing with GenBank database. Conclusion: Twenty-one EST denote that radioresistance correlative genes may be in IRM-2 mouse, which have laid a foundation for isolating and identifying radioresistance correlative genes in further study. (authors)

Contrasting Roles of Islet Resident Immunoregulatory Macrophages and Dendritic Cells in Experimental Autoimmune Type 1 Diabetes.

Directory of Open Access Journals (Sweden)

Thomas B Thornley

Full Text Available The innate immune system critically shapes diabetogenic adaptive immunity during type 1 diabetes (T1D pathogenesis. While the role of tissue-infiltrating monocyte-derived macrophages in T1D is well established, the role of their tissue-resident counterparts remains undefined. We now demonstrate that islet resident macrophages (IRMs from non-autoimmune mice have an immunoregulatory phenotype and powerfully induce FoxP3+ Tregs in vitro. The immunoregulatory phenotype and function of IRMs is compromised by TLR4 activation in vitro. Moreover, as T1D approaches in NOD mice, the immunoregulatory phenotype of IRMs is diminished as is their relative abundance compared to immunostimulatory DCs. Our findings suggest that maintenance of IRM abundance and their immunoregulatory phenotype may constitute a novel therapeutic strategy to prevent and/or cure T1D.

Examination of heterogeneous societies: Identifying subpopulations by contrasting cultures

DEFF Research Database (Denmark)

Glückstad, Fumiko Kano; Schmidt, Mikkel Nørgaard; Mørup, Morten

2017-01-01

, the infinite relational model (IRM) is a new and disruptive type of unsupervised clustering approach that has been developed recently by cognitive psychologists and computer scientists. In this article, an extended version of the IRM coined the multinominal IRM—or mIRM in short—is applied to a cross......-cultural analysis of survey data available from the World Value Survey organization. Specifically, the present work analyzes response patterns of the Portrait Value Questionnaire (PVQ) representing Schwartz’s 10 basic values of Japanese and Swedes. The applied model exposes heterogeneous structures of the two...

Imazapyr-resistant maize technology adoption for witch weed control ...

African Journals Online (AJOL)

Saharan Africa. A new technology known as imazapyr-resistant maize (IRM) has proven to be effective in controlling it. This study examined the status of IRM adoption in western Kenya. A cross sectional survey that included 600 households, ...

Strategic Information Resources Management: Fundamental Practices.

Science.gov (United States)

Caudle, Sharon L.

1996-01-01

Discusses six fundamental information resources management (IRM) practices in successful organizations that can improve government service delivery performance. Highlights include directing changes, integrating IRM decision making into a strategic management process, performance management, maintaining an investment philosophy, using business…

7 CFR 1942.9 - Planning, bidding, contracting, and constructing. [See §§ 1942.17(p) and 1942.18

Science.gov (United States)

2010-01-01

... 7 Agriculture 13 2010-01-01 2009-01-01 true Planning, bidding, contracting, and constructing. [See...) ASSOCIATIONS Community Facility Loans § 1942.9 Planning, bidding, contracting, and constructing. [See §§ 1942....18(l) of this subpart will not be considered when an FmHA or its successor agency under Public Law...