WorldWideScience

Sample records for introduction fifteen years

  1. Adult herpes simplex encephalitis: fifteen years' experience.

    Science.gov (United States)

    Riera-Mestre, Antoni; Gubieras, Laura; Martínez-Yelamos, Sergio; Cabellos, Carmen; Fernández-Viladrich, Pedro

    2009-03-01

    Herpes simplex encephalitis (HSE) is the most frequent cause of sporadic necrotizing encephalitis in adults. The aim of this study is to describe the characteristics of HSE and the factors influencing its outcome. Retrospective study of patients diagnosed with HSE in a tertiary care teaching hospital over a 15-year period. Diagnosis was based on a consistent clinical profile for HSE, plus either a PCR-positive CSF HSV study or consistent brain neuroimaging findings. Patients were divided into 2 groups according to the modified Rankin Scale: good outcome (Grades =3). Thirty-five patients were included. Mean age was 53.9 years. More than half presented febricula or fever, headache, disorientation, behavioral changes, decreased level of consciousness, or neurological deficit. CSF glucose concentration was normal in all patients and WBC count was normal in 8 (23%). PCR for HSV was positive in 92% and cranial MRI was suggestive of HSE in 100% of patients. Mortality was 8.6%. In relation to outcome, age (OR=1.079; 95% CI, 1.023-1.138) and serum albumin level at admission (OR=0.87; 95% CI, 0.794-0.954) were independent prognostic factors at discharge. At 6 months, days of fever after initiation of acyclovir therapy (OR=1.219; 95% CI, 1.046-1.422) and serum albumin level at admission (OR=0.917; 95% CI, 0.87-0.967) were independent prognostic factors. Normal brain MRI or detection of low CSF glucose concentration requires consideration of diagnoses other than HSE. Age, serum albumin level at admission, and days of fever after initiation of acyclovir therapy were independent prognostic factors of the disease.

  2. Morocco's Job Market Policy Over the Last Fifteen Years: Graduate ...

    African Journals Online (AJOL)

    This paper's aim is to discuss Morocco's last fifteen years' job market policy and youth recruitment in the public sector. It is a know fact that there are youths who struggled before being recruited in the public sector, this paper will attend to the effects of three successive governments' policies on the Moroccan labour market.

  3. Fifteen Years of Democracy, 1999-2014: Reflections on Nigeria's ...

    African Journals Online (AJOL)

    This paper examined fifteen years of Nigerian democracy and its reflection on national integration, which is one of the basic dividends expected of any democratic system. The paper aims to bring to the fore why and how Nigerian democracy since 1999 to date is yet to put in place integrative mechanism for its divergent but ...

  4. Collective dose scenario at MAPS - a fifteen year experience

    International Nuclear Information System (INIS)

    Mohan, V.; Viswambharam, K.R.; Mohandas, P.G.; Chudalayandi, K.; Krishnamoorthy, S.

    1999-01-01

    Madras Atomic Power Station - a two unit PHWR- has provided a large data based on occupational exposure since 1983. ICRP-1990 recommendations have forced ALARA practices to be implemented seriously at MAPS to put a check on collective dose. In this paper, an analysis of collective dose has been made with fifteen years of experience in background (1983-97). The distribution of collective dose among different groups shows definite trend over the years. Focus has been made to identify the critical work group, critical jobs, critical work areas, critical radionuclides and the critical systems vis-a-vis the collective dose. Distribution of dose is off-centered, resulting in selective groups (casual workers, mechanical and operation) getting more than sixty percent of station dose and therefore these groups require special focus on dose reduction strategies. There is a reduction in collective dose by a factor of 2 to 5 in different jobs due to refining work procedures and other ALARA efforts. (author)

  5. Fifteen years of radioactive waste management at Ontario Hydro

    International Nuclear Information System (INIS)

    Carter, T.J.; Rao, P.K.M.

    1985-01-01

    Ontario Hydro is a large Canadian utility producing 84% (7394 MWe) of the Nuclear Electricity generated in Canada. The low- and intermediate-level radioactive wastes generated by the Ontario Hydro program are currently being managed at the Bruce Nuclear Power Development with various volume reduction, packaging and interim storage systems. Ontario Hydro also owns and operates a radioactive waste transportation system. Studies are in progress for final disposal of these wastes in a suitable geology in Ontario. Since its inception in 1971, Ontario Hydro's radioactive waste management program has evolved into providing a full fledged radioactive waste management capability to the utility's two nuclear generation centres at Pickering and Bruce, and later in the decade, to Darlington. This paper summarizes the various developments in this program; highlights the major facilities both in-service and planned to be built; reviews the experiences gained over fifteen years of in-house waste management; and discusses the proposed reorientation towards ultimate disposal of these wastes. 2 refs., 8 figs., 1 tab

  6. Will the next fifteen years of high energy physics match the last fifteen

    International Nuclear Information System (INIS)

    Bjorken, J.D.

    1985-09-01

    A brief retrospective of advances in high energy physics made during the last 15 years, both theortical and experimental, is given, followed by predictions for future work, which is said to include testing the standard model and exploring the Higgs sector. The theoretical methods available for understanding the Higgs sector are briefly discussed, as well as available experimental tools

  7. Will the next fifteen years of high energy physics match the last fifteen

    Energy Technology Data Exchange (ETDEWEB)

    Bjorken, J.D.

    1985-09-01

    A brief retrospective of advances in high energy physics made during the last 15 years, both theortical and experimental, is given, followed by predictions for future work, which is said to include testing the standard model and exploring the Higgs sector. The theoretical methods available for understanding the Higgs sector are briefly discussed, as well as available experimental tools. (LEW)

  8. Banking concentration in the European Union during the last fifteen years

    Directory of Open Access Journals (Sweden)

    Santillán-Salgado Roberto J.

    2011-01-01

    Full Text Available The increase in the concentration of the banking industry across European Union countries during the last fifteen years can be explained in terms of: a global factors, like the comprehensive adoption of technological innovations, the intensification of competition that has resulted from the deregulation of the financial sector and, more recently, as a consequence of the government interventions and forced acquisitions prompted by the 2007-2009 financial crisis; and, b factors that have been specific to the E.U., in particular, the structural changes that took place in the region as a result of the creation of the Single Financial Market (1993 and the introduction of the euro (1999. This work analyzes the concentration process of the banking industry in the E.U. during the last fifteen years giving preeminence to the strategic choices made by the region’s commercial banks. It also reports the most visible E.U. banks’ M&As and government interventions that resulted from the 2007-2009 financial crisis, make a preliminary evaluation of the outcomes, and suggests possible future trends for the banking industry in the region.

  9. Histology types of chest wall tumours: Fifteen year single center ...

    African Journals Online (AJOL)

    Materials and Methods: We performed a retrospective study of chest wall tumours at our institution(NCTCE, UNTH, Enugu, Nigeria), for a period of 15 years, spanning October, 2001 to September, 2015.The pathologic reports were retrieved from the hospital pathology archives and correlated with patients' copies in the ...

  10. Fifteen Years Evaluation Of Haematocrit Values In Clients Accepting ...

    African Journals Online (AJOL)

    The study retrospectively evaluated the haematocrit values of clients accepting female sterilization over a 15year period in Jos University Teaching Hospital, Jos, Plateau State, Nigeria. Between January 1985 and December 1999, 2986 female sterilizations, through minilaparotomy, were performed. The mean (± SD) age ...

  11. The history of Korean Institute Chemical Engineers for fifteen years

    International Nuclear Information System (INIS)

    2012-12-01

    This book reports the history of Korean Institute of Chemical Engineers with commemorative message, three congratulatory address and photos for fifty years. Nest, it consists of five chapters, which deals with development this institute by chronological classification. It reports the development history by activity such as education, research, publishing branch, international activity, data, woman, and executive office. It records challenge of chemical engineering, remembrance for past presidents and appendixes on history and a list of members.

  12. Proteomics Standards Initiative: Fifteen Years of Progress and Future Work.

    Science.gov (United States)

    Deutsch, Eric W; Orchard, Sandra; Binz, Pierre-Alain; Bittremieux, Wout; Eisenacher, Martin; Hermjakob, Henning; Kawano, Shin; Lam, Henry; Mayer, Gerhard; Menschaert, Gerben; Perez-Riverol, Yasset; Salek, Reza M; Tabb, David L; Tenzer, Stefan; Vizcaíno, Juan Antonio; Walzer, Mathias; Jones, Andrew R

    2017-12-01

    The Proteomics Standards Initiative (PSI) of the Human Proteome Organization (HUPO) has now been developing and promoting open community standards and software tools in the field of proteomics for 15 years. Under the guidance of the chair, cochairs, and other leadership positions, the PSI working groups are tasked with the development and maintenance of community standards via special workshops and ongoing work. Among the existing ratified standards, the PSI working groups continue to update PSI-MI XML, MITAB, mzML, mzIdentML, mzQuantML, mzTab, and the MIAPE (Minimum Information About a Proteomics Experiment) guidelines with the advance of new technologies and techniques. Furthermore, new standards are currently either in the final stages of completion (proBed and proBAM for proteogenomics results as well as PEFF) or in early stages of design (a spectral library standard format, a universal spectrum identifier, the qcML quality control format, and the Protein Expression Interface (PROXI) web services Application Programming Interface). In this work we review the current status of all of these aspects of the PSI, describe synergies with other efforts such as the ProteomeXchange Consortium, the Human Proteome Project, and the metabolomics community, and provide a look at future directions of the PSI.

  13. DMPD: NF-kappaB activation by reactive oxygen species: fifteen years later. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 16723122 NF-kappaB activation by reactive oxygen species: fifteen years later. Gloi...svg) (.html) (.csml) Show NF-kappaB activation by reactive oxygen species: fifteen years later. PubmedID 167...23122 Title NF-kappaB activation by reactive oxygen species: fifteen years later.

  14. A Fifteen-Year Retrospective Study Of The Prevalence Of Rabies In ...

    African Journals Online (AJOL)

    Records of rabies cases from the 20 Local Government Areas (LGAs) of Bauchi State for fifteen years (1987-2001) were analyzed for trend of exposure. A total of 44 cases of rabies were recorded. Sixty two animals from various species were involved in clinical form of rabies. Out of these, 58 (93.6%) were dogs, 3 (4.8%) ...

  15. Physical activity levels and patterns of thirteen to fifteen year old ...

    African Journals Online (AJOL)

    There is worldwide concern over the decline in physical activity (PA) levels among school children. The purpose of this study was to investigate the (PA) levels and PA patterns of thirteen to fifteen year old boys from different race groups in the North- West Province and to determine to what degree this physical activity profile ...

  16. The Lost Art of Regulated tolerance? Fifteen Years of Regulating Vices in Amsterdam

    NARCIS (Netherlands)

    Huisman, W.; Nelen, J.M.

    2014-01-01

    Fifteen years ago, Brants explored the idiosyncrasies of Dutch policy with regard to prostitution, focusing on the situation in the Dutch capital. Amsterdam was on the brink of the enactment of new policies and legislation regarding the legalization of prostitution and the crackdown on organized

  17. THE EFFECTS OF THE TRAINING IN THE PREPARATION PERIOD ON THE DRIBBLING SPEED WITH FIFTEEN YEARS OLD FOOTBALL PLAYERS

    Directory of Open Access Journals (Sweden)

    Jovan Gardašević

    2014-06-01

    Full Text Available Introduction: The main aim of the research was to identify a level of quantitative changes of the dribbling speed with fifteen years old football players under the influence of the programmed football training of a six weeks preparation period. Methods: According to the time orientation this was a longitudinal study with the aim to define in a two timely different points a quantitative changes of the dribbling speed under the influence of the programmed football training with fifteen years old football players under the influence of the programmed training process, which involved a summer preparation period and lasted forty-two days. The training programme covered forty-four training units. The research was made on a sample of 120 fifteen years old football players of cadet rank. For the assessment of ball handling the three tests were used: horizontal ball rebounding from a wall 20s, dribbling speed of the ball in slalom and juggling alternating with both feet in a square space of 1x1m. In the area of comparative statistics, we used discriminant parametric procedure t-test for big paired samples. Results: Based on the numerical values of the t-test it can be concluded that there are no statistically significant differences in all three variables to estimate the dribbling speed. This confirmed the hypothesis that the expected significant positive quantitative changes of situational-motor abilities influenced by the proposed model of training in preparation period with fifteen years old football players. Discussion: In this research the authors were guided by the fact that this kind of training program in preparation period, where dominates the situational model training is very effective in terms of raising the dribbling speed with fifteen years old, because the model that is used in this training period abounds in exercises in which dominates dribbling speed, in stright line and with changes in direction. The obtained results can be directed

  18. Development and use of a fifteen year-old equivalent mathematical phantom for internal dose calculations

    International Nuclear Information System (INIS)

    Jones, R.M.; Poston, J.W.; Hwang, J.L.; Jones, T.D.; Warner, G.G.

    1976-06-01

    The existence of a phantom based on anatomical data for the average fifteen-year-old provides for a proficient means of obtaining estimates of absorbed dose for children of that age. Dimensions representative of an average fifteen-year-old human, obtained from various biological and medical research, were transformed into a mathematical construct of idealized shapes of the exterior, skeletal system, and internal organs of a human. The idealization for an average adult presently in use by the International Commission on Radiological Protection was used as a basis for design. The mathematical equations describing the phantom were developed to be readily adaptable to present-day methods of dose estimation. Typical exposure situations in nuclear medicine have previously been modeled for existing phantoms. With no further development of the exposure model necessary, adaptation to the fifteen-year-old phantom demonstrated the utility of the design. Estimates of absorbed dose were obtained for the administration of two radiopharmaceuticals, /sup 99m/Tc-sulfur colloid and /sup 99m/Tc-DMSA

  19. Co-occurrence of Marfan syndrome and bipolar disorder: A fifteen year follow up.

    Science.gov (United States)

    Jha, Vijendra Nath; Kumar, Manoj; Tarwani, Jatin

    2016-12-01

    Marfan syndrome, a chromosomal disorder, has been commonly associated with schizophrenia but no association with Bipolar affective disorder has been reported in the scientific literature. This case depicts the occurrence of Bipolar affective disorder in a previously undiagnosed case of Marfan syndrome. In this case patient had all manic episodes without any depressive or schizophrenia-like episodes, suggesting a diagnostic stability over a long period of over fifteen years. Studies and research are needed in this regard to look for any possible potential association between the two illnesses. Copyright © 2016 Elsevier B.V. All rights reserved.

  20. A historical perspective on fifteen years of laser damage thresholds at LLNL

    International Nuclear Information System (INIS)

    Rainer, F.; De Marco, F.P.; Staggs, M.C.; Kozlowski, M.R.; Atherton, L.J.; Sheehan, L.M.

    1993-01-01

    We have completed a fifteen year, referenced and documented compilation of more than 15,000 measurements of laser-induced damage thresholds (LIDT) conducted at the Lawrence Livermore National Laboratory (LLNL). These measurements cover the spectrum from 248 to 1064 nm with pulse durations ranging from < 1 ns to 65 ns and at pulse-repetition frequencies (PRF) from single shots to 6.3 kHz. We emphasize the changes in LIDTs during the past two years since we last summarized our database. We relate these results to earlier data concentrating on improvements in processing methods, materials, and conditioning techniques. In particular, we highlight the current status of anti-reflective (AR) coatings, high reflectors (HR), polarizers, and frequency-conversion crystals used primarily at 355 nm and 1064 nm

  1. Beijing fifteen years on: the persistence of barriers to gender mainstreaming in health policy.

    Science.gov (United States)

    Payne, Sarah

    2011-01-01

    In 2010, fifteen years after the Beijing declaration on women's rights, the UN Commission on the Status of Women met to review progress in gender mainstreaming. Reports on gender equality by member states revealed differences in the degree of change achieved in this period, while highlighting common barriers to gender mainstreaming. The same barriers have long been identified by academics and activists, but prove remarkably resistant to strategies to address gender inequalities. This paper reviews approaches to gender mainstreaming in the context of health policy, and suggests that a model of the obstacles to gender mainstreaming, which identifies barriers as essentially pragmatic, conceptual, or political in origin, might enable a more explicit discussion of the factors underlying this resistance and the ways in which they might be challenged.

  2. Fifteen Years of Slow Slip and Tremor Observations at the Northern Costa Rica Subduction Zone

    Science.gov (United States)

    Schwartz, S. Y.; Dixon, T. H.; Protti, M.; González, V. M.

    2015-12-01

    Coordinated long-term geophysical observations at the northern Costa Rica seismogenic zone, facilitated by NSF's MARGINS program, have greatly expanded our understanding of its megathrust behavior. Here we review fifteen years of seismic, geodetic, ocean bottom fluid flow and pressure sensor data collected on or near the Nicoya Peninsula, above the shallow thrust interface that document a variety of slow slip behaviors. These include relatively deep (~30-40 km), large slow slip events that occur about every 2 years, smaller events that locate at more intermediate depth (10-15 km) and occur more frequently (~1 per year), and very shallow events at the toe of the margin wedge that produce no discernible GPS signal on land but are detected on seafloor pressure sensors. Most of these slow slip events at the toe are accompanied by seismic tremor. Short-term, GPS only observations might have detected a few of these slow slip events; however, the longer more diverse instrument deployment was necessary to reveal their greater complexity. This demonstrates the need for a sustained, multi-instrument deployment and off-shore instrumentation at several different subduction zones, like that proposed for the Subduction Zone Observatory (SZO), to significantly advance our understanding of slow slip at convergent boundaries. Similar instrumentation to what exists in Nicoya is presently being established in the Osa-Burica region of southern Costa Rica to capture earthquake cycle deformation there. These two installations can provide a good nucleus for a larger circum-Pacific SZO effort.

  3. Fifteen years of GH replacement improves body composition and cardiovascular risk factors.

    Science.gov (United States)

    Elbornsson, Mariam; Götherström, Galina; Bosæus, Ingvar; Bengtsson, Bengt-Åke; Johannsson, Gudmundur; Svensson, Johan

    2013-05-01

    Few studies have determined the effects of more than 5-10 years of GH replacement in adults on body composition and cardiovascular risk factors. In this prospective, single-center, open-label study, the effects of 15 years of GH replacement on body composition and cardiovascular risk factors were determined in 156 hypopituitary adults (93 men) with adult-onset GH deficiency (GHD). Mean age was 50.5 (range 22-74) years at study start. Body composition was measured using dual-energy X-ray absorptiometry. The mean initial GH dose of 0.55 (S.E.M. 0.03) mg/day was gradually lowered to 0.40 (0.01) mg/day after 15 years. The mean serum IGF1 SDS increased from -1.53 (0.10) at baseline to 0.74 (0.13) at study end (Plevel at study end (Pbody fat (BF) started to increase and had returned to the baseline level after 15 years. Serum levels of total cholesterol and LDL-cholesterol decreased and serum HDL-cholesterol level increased. Fasting plasma glucose increased from 4.4 (0.1) at baseline to 4.8 (0.1) mmol/l at study end (P<0.001). However, blood HbA1c decreased from 5.0 (0.1) to 4.6 (0.1) % (P<0.001). Fifteen-year GH replacement in GHD adults induced a transient decrease in BF and sustained improvements of LST and serum lipid profile. Fasting plasma glucose increased whereas blood HbA1c was reduced.

  4. Designing for Safety: Implications of a Fifteen Year Review of Swallowed and Aspirated Dentures.

    Science.gov (United States)

    Kent, Samuel J W; Mackie, James; Macfarlane, Tatiana V

    2016-01-01

    Dentures are worn by around 20% of the population, yet if they become displaced they may enter the gastrointestinal or respiratory system, sometimes with grave consequences. The aim of this study was to review recent published literature in order to identify the epidemiology of patients and characteristics of swallowed and aspirated dental prostheses, and propose strategies to minimise these risks. A fifteen year retrospective of published case series and case reports was carried out. Photographs, radiographs and descriptions of the dental prostheses were gathered, as well as the patient's presenting complaint, the anatomical site where the denture was caught and the procedure required to remove the denture. Ninety one separate events of swallowed or aspirated dentures were identified from 83 case reports and series from 28 countries. Average age was 55 years, and these were 74% male. Photographs were retrieved for 49 of these dentures. Clasps were present in 25 of the dentures. There was no significant difference between clasped and unclasped dentures for perforation rates, need for open surgery and spontaneously passed dentures. We discuss the implications of this study regarding denture designs, specifically the importance of using a radiopaque acrylic, using clasps when required even if there is a risk of aspiration, advising patients to return if a denture is loose or damaged, and finally that all patients who wear a denture are at risk of aspiration and swallowing events, and associated morbidity and mortality.

  5. Designing for Safety: Implications of a Fifteen Year Review of Swallowed and Aspirated Dentures

    Directory of Open Access Journals (Sweden)

    Samuel J. W. Kent

    2016-06-01

    Full Text Available Objectives: Dentures are worn by around 20% of the population, yet if they become displaced they may enter the gastrointestinal or respiratory system, sometimes with grave consequences. The aim of this study was to review recent published literature in order to identify the epidemiology of patients and characteristics of swallowed and aspirated dental prostheses, and propose strategies to minimise these risks. Material and Methods: A fifteen year retrospective of published case series and case reports was carried out. Photographs, radiographs and descriptions of the dental prostheses were gathered, as well as the patient’s presenting complaint, the anatomical site where the denture was caught and the procedure required to remove the denture. Results: Ninety one separate events of swallowed or aspirated dentures were identified from 83 case reports and series from 28 countries. Average age was 55 years, and these were 74% male. Photographs were retrieved for 49 of these dentures. Clasps were present in 25 of the dentures. There was no significant difference between clasped and unclasped dentures for perforation rates, need for open surgery and spontaneously passed dentures. Conclusions: We discuss the implications of this study regarding denture designs, specifically the importance of using a radiopaque acrylic, using clasps when required even if there is a risk of aspiration, advising patients to return if a denture is loose or damaged, and finally that all patients who wear a denture are at risk of aspiration and swallowing events, and associated morbidity and mortality.

  6. Atypical presentation of Legionella pneumonia among patients with underlying cancer: A fifteen-year review.

    Science.gov (United States)

    del Castillo, Maria; Lucca, Anabella; Plodkowski, Andrew; Huang, Yao-Ting; Kaplan, Janice; Gilhuley, Kathleen; Babady, N Esther; Seo, Susan K; Kamboj, Mini

    2016-01-01

    Immunocompromised patients, especially those receiving treatment with corticosteroids and cytotoxic chemotherapy are at increased risk for developing Legionella pneumonia. The aim of this study was to determine clinical and radiographic characteristics of pulmonary infection due to Legionella in persons undergoing treatment for cancer and stem cell transplant (SCT) recipients. Retrospective review of Legionella cases at MSKCC over a fifteen-year study period from January 1999 and December 2013. Cases were identified by review of microbiology records. During the study period, 40 cases of Legionella infection were identified; nine among these were due to non-pneumophila species. Most cases occurred during the summer. The majority [8/9, (89%)] of patients with non-pneumophila infection had underlying hematologic malignancy, compared to 18/31 (58%) with Legionella pneumophila infections. Radiographic findings were varied-nodular infiltrates mimicking invasive fungal infection were seen only among patients with hematologic malignancy and hematopoietic stem cell transplant (SCT) recipients and were frequently associated with non-pneumophila infections (50% vs 16%; P = 0.0594). All cases of nodular Legionella pneumonia were found incidentally or had an indolent clinical course. Legionella should be considered in the differential diagnosis of nodular lung lesions in immunocompromised patients, especially those with hematologic malignancy and SCT recipients. Most cases of nodular disease due to Legionella are associated with non-pneumophila infections. Copyright © 2015 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

  7. Purity, Victimhood and Agency: Fifteen years of the UN Trafficking Protocol

    Directory of Open Access Journals (Sweden)

    Marjan Wijers

    2015-04-01

    Full Text Available When the women’s movement reverted back to the nineteenth-century Victorian concept of ‘trafficking in women’ to address abuses of migrant women in the sex industry, it unwittingly adopted not only a highly morally biased concept—dividing women into innocent victims in need of rescue and guilty ones who can be abused with impunity—but also one with racist and nationalistic overtones. Despite efforts to counter these flaws, this inheritance continues to define the debate on trafficking today, exemplified by the distinction made by the United Nations Trafficking Protocol between so-called ‘sexual exploitation’ and ‘labour exploitation’ and its focus on the aspects of recruitment and movement. As a result, its implementation in the last fifteen years has led to a range of oppressive measures against sex workers and migrants in the name of combating trafficking. The focus on the purity and victimhood of women, coupled with the protection of national borders, not only impedes any serious effort to address the exploitation of human beings under forced labour and slavery-like conditions, but actually causes harm. The call of the anti-trafficking movement for a human rights-based approach does not necessarily solve these fundamental problems, as it tends to restrict itself to protecting the rights of trafficked persons, while neglecting or even denying the human rights of sex workers and migrants.

  8. Fifteen year phenological plant species and meteorological trends in central Italy

    Science.gov (United States)

    Orlandi, F.; Bonofiglio, T.; Ruga, L.; Romano, B.; Fornaciari, M.

    2012-04-01

    The present study was carried out in a phenological garden located near Perugia, central Italy, which contains vegetative clones of plant species, common to several international phenological gardens such as: Cornus sanguinea L.; Corylus avellana L.; Ligustrum vulgare L.; Robinia pseudoacacia L.; Salix acutifolia Willd.; Sambucus nigra L. The vegetative plant growth monitoring was realized week by week using common international keys: V3) bud break and leaf unfolding; V5) young unfolded leaf; V7) adult leaves; V8) beginning of leaf colouring. The phenological dates thus obtained provide a model of development for the different species in relationship to the fifteen-year period of observation (1997-2011). By a meteorological point of view the principal temperature and rain trends were studied showing as the highest anomalies during the study period were those recorded during the first months of the year (January and February). The phenological data evidenced a double trend behaviour considering the two central phases (V5-V7) in comparison to the other ones (V3-V8). In general, a quite invariance in the manifestation of the open bud phase and a contemporary advance of the young open leaves phase particularly from 2006 was recorded, with a shortening of the leaf opening period probably due to more rapid spring temperature increase in the last years. The delay tendency of V7 phase in particular evidenced the presence of growing leaves till summer weeks monitoring young leaves for a long time On the contrary, the V8 (autumn leaf colouring) phase tend to remain constant, with the exception of some species such as Corylus and Cornus which showed variations of this phase, showing as the signal for leaf colouring in fall is quite ambiguous and less evident. The lowest correlations between annual vegetative phases and temperature variations were manifested above all by two species (Sambucus nigra L. and Robinia pseudoacacia L.) for which the first leaf development phases

  9. Characterising fifteen years of continuous atmospheric radon activity observations at Cape Point (South Africa)

    Science.gov (United States)

    Botha, R.; Labuschagne, C.; Williams, A. G.; Bosman, G.; Brunke, E.-G.; Rossouw, A.; Lindsay, R.

    2018-03-01

    This paper describes and discusses fifteen years (1999-2013) of continuous hourly atmospheric radon (222Rn) monitoring at the coastal low-altitude Southern Hemisphere Cape Point Station in South Africa. A strong seasonal cycle is evident in the observed radon concentrations, with maxima during the winter months, when air masses arriving at the Cape Point station from over the African continental surface are more frequently observed, and minima during the summer months, when an oceanic fetch is predominant. An atmospheric mean radon activity concentration of 676 ± 2 mBq/m3 is found over the 15-year record, having a strongly skewed distribution that exhibits a large number of events falling into a compact range of low values (corresponding to oceanic air masses), and a smaller number of events with high radon values spread over a wide range (corresponding to continental air masses). The mean radon concentration from continental air masses (1 004 ± 6 mBq/m3) is about two times higher compared to oceanic air masses (479 ± 3 mBq/m3). The number of atmospheric radon events observed is strongly dependent on the wind direction. A power spectral Fast Fourier Transform analysis of the 15-year radon time series reveals prominent peaks at semi-diurnal, diurnal and annual timescales. Two inter-annual radon periodicities have been established, the diurnal 0.98 ± 0.04 day-1 and half-diurnal 2.07 ± 0.15 day-1. The annual peak reflects major seasonal changes in the patterns of offshore versus onshore flow associated with regional/hemispheric circulation patterns, whereas the diurnal and semi-diurnal peaks together reflect the influence of local nocturnal radon build-up over land, and the interplay between mesoscale sea/land breezes. The winter-time diurnal radon concentration had a significant decrease of about 200 mBq/m3 (17%) while the summer-time diurnal radon concentration revealed nearly no changes. A slow decline in the higher radon percentiles (75th and 95th) for the

  10. Fifteen years of typhoid perforation in children in Ibadan: still a ...

    African Journals Online (AJOL)

    Objective: To study the disease of typhoid in children over a significant period of time, in this case, 15 years to see whether there have been any changes in presentation, mode of treatment, morbidity and mortality rates. Method: A retrospective study of 183 children operated on for typhoid ileal perforation in 15 years.

  11. The Prevalence and Incidence of Glaucoma in Denmark in a Fifteen Year Period

    DEFF Research Database (Denmark)

    Kolko, Miriam; Horwitz, Anna; Thygesen, John

    2015-01-01

    PURPOSE: The purpose of the present study was to describe the prevalence, incidence and geographic variation of glaucoma in Denmark in the period from 1996 to 2011. Moreover, the aim was to identify the treatment patterns of glaucoma within the studied period. METHODS: All Danish citizens were...... included throughout the study period. The National Prescription Registry was used to identify all claimed prescriptions for glaucoma medication. RESULTS: A total of 116,592 incident glaucoma patients were identified. Average age at onset was 66 years (range: 0-105 years), 55% were women. The prevalence...... of glaucoma increased from 0.79% to 1.72% during the investigated period. In 2011 glaucoma affected 3.76% of the population above 50 years and 10% in patients above 80 years. The age-specific incidence rate of glaucoma seemed to be constant and the increasing prevalence was primarily attributed to an aging...

  12. From infancy to adolescence: fifteen years of continuous treatment with hydroxyurea in sickle cell anemia.

    Science.gov (United States)

    Hankins, Jane S; Aygun, Banu; Nottage, Kerri; Thornburg, Courtney; Smeltzer, Matthew P; Ware, Russell E; Wang, Winfred C

    2014-12-01

    Despite documented laboratory and clinical benefits of hydroxyurea for children with sickle cell anemia (SCA), the drug's long-term safety and efficacy remains poorly defined. The HUSOFT trial and extension study examined feasibility, toxicity, and hematological efficacy of hydroxyurea in infants with SCA. This report describes HUSOFT participants who have continued hydroxyurea therapy for 15 years. With IRB approval, medical records were reviewed for clinical, laboratory, and growth parameters. Twenty-eight infants enrolled in the original 2-year HUSOFT study received open-label liquid hydroxyurea at 20 mg/kg/day; 17 completed the extension study with dose escalation to 30 mg/kg/day. Eight of these 17 (6 girls and 2 boys, all HbSS) have continued on daily hydroxyurea for at least 15 years (median age at last follow-up 17.6 years) without interruption. All hematologic indices (Hb concentration, mean corpuscular volume (MCV), fetal hemoglobin) showed sustained effect after 15 years. The median maximum tolerated dose of hydroxyurea has decreased from 30 to 26 mg/kg/day (range 19.5-31.2); neutropenia [absolute neutrophil count (ANC)hydroxyurea therapy since infancy appears safe and efficacious in SCA.

  13. Fifteen-year experience of testicular neoplasm in a regional centre.

    Science.gov (United States)

    Dodds, L J; Murphy, D; Neerhut, G; Leggatt, R

    1997-12-01

    During a 15-year period from 1980 to 1995, 63 patients from the Geelong region of Victoria presented with germ cell neoplasm. In this retrospective review performed by studying hospital records, treating specialists' notes and by telephone interviews, 61 of 63 patients were identified. A tumour incidence of four cases per 100,000 male population per year with an overall cancer-specific survival of 95% is demonstrated. Follow-up ranged from 18 months to 15 years. The incidence of seminoma was 30%; patients with seminoma presented at a later stage than those with non-seminoma. The present study demonstrates the increasing incidence of testicular tumour in the Geelong region, and the excellent prognosis of this disease with management outside of the tertiary referral centre.

  14. Fifteen years of cold matter on the atom chip: promise, realizations, and prospects

    Science.gov (United States)

    Keil, Mark; Amit, Omer; Zhou, Shuyu; Groswasser, David; Japha, Yonathan; Folman, Ron

    2016-01-01

    Here we review the field of atom chips in the context of Bose–Einstein Condensates (BEC) as well as cold matter in general. Twenty years after the first realization of the BEC and 15 years after the realization of the atom chip, the latter has been found to enable extraordinary feats: from producing BECs at a rate of several per second, through the realization of matter-wave interferometry, and all the way to novel probing of surfaces and new forces. In addition, technological applications are also being intensively pursued. This review will describe these developments and more, including new ideas which have not yet been realized. PMID:27499585

  15. Fifteen-Year Radiotherapy Outcomes of the Randomized PORTEC-1 Trial for Endometrial Carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Creutzberg, Carien L., E-mail: c.l.creutzberg@lumc.nl [Department of Clinical Oncology, Leiden University Medical Center (Netherlands); Nout, Remi A. [Department of Clinical Oncology, Leiden University Medical Center (Netherlands); Lybeert, Marnix L.M. [Department of Radiotherapy, Catharina Hospital Eindhoven (Netherlands); Warlam-Rodenhuis, Carla C. [Department of Radiation Oncology, University Medical Center Utrecht (Netherlands); Jobsen, Jan J. [Department of Radiotherapy, Medisch Spectrum Twente, Enschede (Netherlands); Mens, Jan-Willem M. [Department of Radiation Oncology, ErasmusMC-Daniel den Hoed Cancer Center, Rotterdam (Netherlands); Lutgens, Ludy C.H.W. [MAASTRO clinic, Maastricht (Netherlands); Pras, Elisabeth [Department of Radiotherapy, University Medical Center Groningen (Netherlands); Poll-Franse, Lonneke V. van de [Comprehensive Cancer Centre South, Eindhoven and Center of Research on Psychology in Somatic Diseases, Tilburg University (Netherlands); Putten, Wim L.J. van [Department of Biostatistics, ErasmusMC-Daniel den Hoed Cancer Center, Rotterdam (Netherlands)

    2011-11-15

    Purpose: To evaluate the very long-term results of the randomized Post Operative Radiation Therapy in Endometrial Carcinoma (PORTEC)-1 trial for patients with Stage I endometrial carcinoma (EC), focusing on the role of prognostic factors for treatment selection and the long-term risk of second cancers. Patients and Methods: The PORTEC trial (1990-1997) included 714 patients with Stage IC Grade 1-2 or Stage IB Grade 2-3 EC. After surgery, patients were randomly allocated to external-beam pelvic radiotherapy (EBRT) or no additional treatment (NAT). Analysis was by intention to treat. Results: 426 patients were alive at the date of analysis. The median follow-up time was 13.3 years. The 15-year actuarial locoregional recurrence (LRR) rates were 6% for EBRT vs. 15.5% for NAT (p < 0.0001). The 15-year overall survival was 52% vs. 60% (p = 0.14), and the failure-free survival was 50% vs. 54% (p = 0.94). For patients with high-intermediate risk criteria, the 15-year overall survival was 41% vs. 48% (p = 0.51), and the 15-year EC-related death was 14% vs. 13%. Most LRR in the NAT group were vaginal recurrences (11.0% of 15.5%). The 15-year rates of distant metastases were 9% vs. 7% (p = 0.25). Second primary cancers had been diagnosed over 15 years in 19% of all patients, 22% vs. 16% for EBRT vs. NAT (p = 0.10), with observed vs. expected ratios of 1.6 (EBRT) and 1.2 (NAT) compared with a matched population (p = NS). Multivariate analysis confirmed the prognostic significance of Grade 3 for LRR (hazard ratio [HR] 3.4, p = 0.0003) and for EC death (HR 7.3, p < 0.0001), of age >60 (HR 3.9, p = 0.002 for LRR and 2.7, p = 0.01 for EC death) and myometrial invasion >50% (HR 1.9, p = 0.03 and HR 1.9, p = 0.02). Conclusions: The 15-year outcomes of PORTEC-1 confirm the relevance of HIR criteria for treatment selection, and a trend for long-term risk of second cancers. EBRT should be avoided in patients with low- and intermediate-risk EC.

  16. Fifteen-Year Follow-Up of Thyroid Status in Adults with Down Syndrome

    Science.gov (United States)

    Prasher, V.; Ninan, S.; Haque, S.

    2011-01-01

    Background: The natural history of thyroid function in adults with Down syndrome is relatively unknown with limited long-term follow-up data. Method: This study investigated annual thyroid function tests in 200 adults with Down syndrome over a 15-year period. Results: For healthy adults with Down syndrome there is a gradual increase in thyroxine…

  17. Fifteen Years of Research on Graduate Education in Economics: What Have We Learned?

    Science.gov (United States)

    Stock, Wendy A.; Siegfried, John J.

    2014-01-01

    In this article, the authors summarize their 15 years of research on graduate education in economics in the United States. They examine all stages of the process, from the undergraduate origins of eventual economics PhDs to their attrition and time-to-degree outcomes. For PhD completers, the authors examine job market outcomes, research…

  18. Fifteen years' experience with the use of artificial chords for valve reconstruction in children

    NARCIS (Netherlands)

    Kluin, Jolanda; Sojak, Vladimir; Koolbergen, David R.; Boon, Rody; Bökenkamp, Regina; Hazekamp, Mark G.

    2017-01-01

    OBJECTIVES: To retrospectively review our experience with artificial chords in mitral and tricuspid reconstructive surgery in children. METHODS: All consecutive paediatric ( <18 years) patients who underwent mitral or tricuspid valve reconstruction with the use of artificial chords in our centre in

  19. Fifteen years of the Family Eating and Activity Habits Questionnaire (FEAHQ): an update and review.

    Science.gov (United States)

    Golan, M

    2014-04-01

    The Family Eating and Activity Habits Questionnaire (FEAHQ) is a 32-item self-report instrument designed to assess the eating and activity habits of family members as well as obesogenic factors in the overall home environment (stimulus and behaviour patterns) related to weight. Originally, this questionnaire, which was developed in Israel, was designed for use in family-based weight-management interventions that emphasized changes in the environment, and in parents' knowledge, behaviours and modelling. It was developed for use with children aged 6-11 years and designed for co-completion by parents or caretakers and their children. Over the years, it has been administered in research and clinical settings in Israel, England, Australia and other countries. Its 15-year anniversary calls for an update in the literature regarding adjustments made to improve its use in different settings and with different ethnic populations and the psychometric properties of the revised version. The goal of this paper is threefold: (i) to describe the history and development of the FEAHQ; (ii) to present new data supporting the psychometric properties of the subscales of the Revised FEAHQ (FEAHQ-R) for ages 6-12 years and (iii) to review the clinical and research literature reporting on FEAHQ subscales. The psychometric properties of the revised questionnaire were evaluated in a randomized control trial and in a naturalistic, community-based study to promote healthy lifestyle among families with children 6-12 years of age from different ethnic populations. The tool demonstrated good test-retest reliability when completed by caretakers and very good internal consistency. The questionnaire scores discriminated between obese and normal-weight children and predicted the weight classification of 66% of the participants. The FEAHQ-R is a useful clinical tool for identifying target behaviors for treatment and monitoring treatment progress that centers on overweight prevention and weight

  20. Vegan-vegetarian low-protein supplemented diets in pregnant CKD patients: fifteen years of experience

    OpenAIRE

    Attini, Rossella; Leone, Filomena; Parisi, Silvia; Fassio, Federica; Capizzi, Irene; Loi, Valentina; Colla, Loredana; Rossetti, Maura; Gerbino, Martina; Maxia, Stefania; Alemanno, Maria Grazia; Minelli, Fosca; Piccoli, Ettore; Versino, Elisabetta; Biolcati, Marilisa

    2016-01-01

    Background Pregnancy in women with advanced CKD becoming increasingly common. However, experience with low-protein diets in CKD patients in pregnancy is still limited. Aim of this study is to review the results obtained over the last 15?years with moderately restricted low-protein diets in pregnant CKD women (combining: CKD stages 3-5, proteinuria: nephrotic at any time, or?>?=1?g/24 at start or referral; nephrotic in previous pregnancy). CKD patients on unrestricted diets were employed for c...

  1. Fifteen-year phenological plant species and meteorological trends in central Italy

    Science.gov (United States)

    Orlandi, F.; Ruga, L.; Bonofiglio, T.; Romano, B.; Fornaciari, M.

    2014-07-01

    The present study was carried out in a phenological garden in central Italy that contains vegetative clones of shrubs and trees common to several international phenological gardens, such as Cornus sanguinea L.; Corylus avellana L.; Ligustrum vulgare L.; Robinia pseudoacacia L.; Salix acutifolia Willd. and Sambucus nigra L. Vegetative plant growth monitoring was carried out weekly using common international keys: BBCH07, bud break and leaf unfolding; BBCH19, young unfolded leaf; BBCH91, adult leaves; BBCH93, beginning of leaf colouring. The phenological dates thus obtained provide a model of the development for these different species in relation to the 15-year period of observation (1997-2011). From a meteorological point of view, temperature and precipitation trends were studied, with the highest anomalies during the study period recorded during the first 2 months of the year (January, February). There was relative invariance in the manifestation of the open bud phase and the contemporary advance of the young open leaves phase, particularly from 2006. This was accompanied by shortening of the leaf opening period, which appeared due to more rapid spring temperature increases over the last few years. The advance tendency of the BBCH91 phase showed adult leaves from the first summer weeks with fully green foliage monitored for a long time. Generally, the autumn leaf colouring phase tended to remain constant, with the exception of Salix acutifolia and Sambucus nigra, for which, on the other hand, the first leaf development phases appeared to be most likely influenced by the photoperiod.

  2. Fifteen-Year Radiotherapy Outcomes of the Randomized PORTEC-1 Trial for Endometrial Carcinoma

    International Nuclear Information System (INIS)

    Creutzberg, Carien L.; Nout, Remi A.; Lybeert, Marnix L.M.; Wárlám-Rodenhuis, Carla C.; Jobsen, Jan J.; Mens, Jan-Willem M.; Lutgens, Ludy C.H.W.; Pras, Elisabeth; Poll-Franse, Lonneke V. van de; Putten, Wim L.J. van

    2011-01-01

    Purpose: To evaluate the very long-term results of the randomized Post Operative Radiation Therapy in Endometrial Carcinoma (PORTEC)-1 trial for patients with Stage I endometrial carcinoma (EC), focusing on the role of prognostic factors for treatment selection and the long-term risk of second cancers. Patients and Methods: The PORTEC trial (1990–1997) included 714 patients with Stage IC Grade 1–2 or Stage IB Grade 2–3 EC. After surgery, patients were randomly allocated to external-beam pelvic radiotherapy (EBRT) or no additional treatment (NAT). Analysis was by intention to treat. Results: 426 patients were alive at the date of analysis. The median follow-up time was 13.3 years. The 15-year actuarial locoregional recurrence (LRR) rates were 6% for EBRT vs. 15.5% for NAT (p 60 (HR 3.9, p = 0.002 for LRR and 2.7, p = 0.01 for EC death) and myometrial invasion >50% (HR 1.9, p = 0.03 and HR 1.9, p = 0.02). Conclusions: The 15-year outcomes of PORTEC-1 confirm the relevance of HIR criteria for treatment selection, and a trend for long-term risk of second cancers. EBRT should be avoided in patients with low- and intermediate-risk EC.

  3. International Conference 'Fifteen Years after the Chornobyl Accident. Lessons Learned'. Abstracts Learning

    International Nuclear Information System (INIS)

    Anon

    2001-01-01

    The main aims of the conference are: for the scientific community in the most affected countries, to develop a common vision with the international scientific community with regard to the consequences of the Chornobyl disaster (in ecological, medical, social and other areas 15 years post-Chornobyl); to drawing conclusions and providing recommendations to allow decision makers at both national and international level to take further steps to mitigate the effects of the disaster. For the results of the Conference, to represent a common international understanding of the current situation resulting from the accident and the future initiatives which will be necessary to counter its effects

  4. Fifteen years SIB Swiss Institute of Bioinformatics: life science databases, tools and support.

    Science.gov (United States)

    Stockinger, Heinz; Altenhoff, Adrian M; Arnold, Konstantin; Bairoch, Amos; Bastian, Frederic; Bergmann, Sven; Bougueleret, Lydie; Bucher, Philipp; Delorenzi, Mauro; Lane, Lydie; Le Mercier, Philippe; Lisacek, Frédérique; Michielin, Olivier; Palagi, Patricia M; Rougemont, Jacques; Schwede, Torsten; von Mering, Christian; van Nimwegen, Erik; Walther, Daniel; Xenarios, Ioannis; Zavolan, Mihaela; Zdobnov, Evgeny M; Zoete, Vincent; Appel, Ron D

    2014-07-01

    The SIB Swiss Institute of Bioinformatics (www.isb-sib.ch) was created in 1998 as an institution to foster excellence in bioinformatics. It is renowned worldwide for its databases and software tools, such as UniProtKB/Swiss-Prot, PROSITE, SWISS-MODEL, STRING, etc, that are all accessible on ExPASy.org, SIB's Bioinformatics Resource Portal. This article provides an overview of the scientific and training resources SIB has consistently been offering to the life science community for more than 15 years. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

  5. Long Term Control of Scabies Fifteen Years after an Intensive Treatment Programme.

    Science.gov (United States)

    Marks, Michael; Taotao-Wini, Betty; Satorara, Lorraine; Engelman, Daniel; Nasi, Titus; Mabey, David C; Steer, Andrew C

    2015-12-01

    Scabies is a major public health problem in the Pacific and is associated with an increased risk of bacterial skin infections, glomerulonephritis and rheumatic fever. Mass drug administration with ivermectin is a promising strategy for the control of scabies. Mass treatment with ivermectin followed by active case finding was conducted in five communities in the Solomon Islands between 1997 and 2000 and resulted in a significant reduction in the prevalence of both scabies and bacterial skin infections. We conducted a prospective follow-up study of the communities where the original scabies control programme had been undertaken. All residents underwent a standardised examination for the detection of scabies and impetigo. Three hundred and thirty eight residents were examined, representing 69% of the total population of the five communities. Only 1 case of scabies was found, in an adult who had recently returned from the mainland. The prevalence of active impetigo was 8.8% overall and 12.4% in children aged 12 years or less. We found an extremely low prevalence of scabies 15 years after the cessation of a scabies control programme. The prevalence of impetigo had also declined further since the end of the control programme. Our results suggest that a combination of mass treatment with ivermectin and intensive active case finding may result in long term control of scabies. Larger scale studies and integration with other neglected tropical disease control programmes should be priorities for scabies control efforts.

  6. Fifteen years of portfolio assessment of dental hygiene student competency: lessons learned.

    Science.gov (United States)

    Gadbury-Amyot, Cynthia C; Bray, Kimberly Krust; Austin, Kylie J

    2014-10-01

    Adoption of portfolio assessment in the educational environment is gaining attention as a means to incorporate self-assessment into the curriculum and to use evidence to support learning outcomes and to demonstrate competency. Portfolios provide a medium for students to demonstrate and document their personal and professional growth across the curriculum. The purpose of this literature review is to discuss the drivers for portfolio education, the benefits to both students and program faculty/administrators, the barriers associated with portfolio use, and suggested solutions that have been determined through several years of "lessons learned." The University of Missouri Kansas City School of Dentistry, Division of Dental Hygiene department has been utilizing portfolio assessment for over 15 years and has collected data related to portfolio performance since 2001. Results from correlational statistics calculated on the 312 dental hygiene students that graduated from 2001 to 2013 demonstrate a positive and significant relationship between portfolio performance and overall GPA as well as portfolio performance and NBDHE scores. Copyright © 2014 The American Dental Hygienists’ Association.

  7. Long Term Control of Scabies Fifteen Years after an Intensive Treatment Programme.

    Directory of Open Access Journals (Sweden)

    Michael Marks

    2015-12-01

    Full Text Available Scabies is a major public health problem in the Pacific and is associated with an increased risk of bacterial skin infections, glomerulonephritis and rheumatic fever. Mass drug administration with ivermectin is a promising strategy for the control of scabies. Mass treatment with ivermectin followed by active case finding was conducted in five communities in the Solomon Islands between 1997 and 2000 and resulted in a significant reduction in the prevalence of both scabies and bacterial skin infections.We conducted a prospective follow-up study of the communities where the original scabies control programme had been undertaken. All residents underwent a standardised examination for the detection of scabies and impetigo.Three hundred and thirty eight residents were examined, representing 69% of the total population of the five communities. Only 1 case of scabies was found, in an adult who had recently returned from the mainland. The prevalence of active impetigo was 8.8% overall and 12.4% in children aged 12 years or less.We found an extremely low prevalence of scabies 15 years after the cessation of a scabies control programme. The prevalence of impetigo had also declined further since the end of the control programme. Our results suggest that a combination of mass treatment with ivermectin and intensive active case finding may result in long term control of scabies. Larger scale studies and integration with other neglected tropical disease control programmes should be priorities for scabies control efforts.

  8. Fifteen years after a ferry disaster: clinical interviews and survivors’ self-assessment of their experience

    Directory of Open Access Journals (Sweden)

    Filip K. Arnberg

    2013-10-01

    Full Text Available Background: Disasters yield increased rates of psychological disorders decades later. Other consequences, however, have received little attention in the past. Objective: We aimed to examine diagnostic status and survivors’ views on disaster-related consequences and social support. Methods: A mixed-methods approach was used with 22 survivors (of 49 eligible 15 years after a ferry disaster. Data collection included audiotaped interviews with open-ended questions and diagnostic assessment of Axis-I disorders. Results: The post-disaster incidence was 54% (12/22 for Axis-I disorders, and 45% (10/22 for full or subsyndromal posttraumatic stress disorder. Thematic analysis revealed that survivor perception of the long-term consequences included positive (character change and negative aspects (being ascribed a survivor identity. Participants’ sought social support for several years, yet many felt hindered by experiential dissimilarity and distress of significant others. Conclusions: Axis-I disorders were prevalent, but not salient to survivors’ perceptions in the long-term. Post-disaster interventions need to attend to common barriers to support.For the abstract or full text in other languages, please see Supplementary files under Article Tools online

  9. Fifteen years of kidney biopsies in children: A single center in Egypt

    Directory of Open Access Journals (Sweden)

    Ashraf Bakr

    2014-01-01

    Full Text Available This study retrospectively investigates the indications and results of renal biopsy in children to determine the patterns of childhood kidney disease in a single tertiary children′s hospital in Egypt. We included all the patients who underwent ultrasound-guided renal biopsy from 1998 to 2012. All the kidney biopsies were studied under light microscopy, while immunofluorescence and electron microscopy were performed when indicated. A total of 1246 renal biopsies were performed over 15 years, on 1096 patients. The mean age of the patients at the time of biopsy was 9.2 ± 3.7 years. The main indication for a biopsy was the steroid-resistant nephrotic syndrome (n = 354, 28.4%, followed by the atypical nephrotic syndrome (n = 250, 20.1%, and renal abnormalities in the systemic diseases (n = 228, 18.3 %. In the 1226 pathologically diagnosed specimens, primary glomerulonephritis was the most common finding (n = 826, 67.4%, followed by secondary glomerulonephritis (n = 238, 19.4%. The most common causes of primary glomerulonephritis were Minimal Change Disease (MCD (n = 267, 21.8%, diffuse proliferative glomerulonephritis (n = 188, 15. 3%, and focal proliferative glomerulonephritis (n = 164, 13.3%. Lupus nephritis (n = 209, 17% was the most common cause of secondary glomerulonephritis. We conclude that the steroid-resistant nephrotic syndrome was the most frequent indication for biopsy and minimal change disease was the most common histopathological finding in our population.

  10. Fifteen years of imposex and tributyltin pollution monitoring along the Portuguese coast.

    Science.gov (United States)

    Laranjeiro, Filipe; Sánchez-Marín, Paula; Oliveira, Isabel Benta; Galante-Oliveira, Susana; Barroso, Carlos

    2018-01-01

    IMO's Anti-Fouling Systems convention banned the use of organotin-based antifouling systems in 2008 as the ultimate effort to stop tributyltin (TBT) inputs into the marine environment. One of the hazardous effects of TBT is imposex (the superimposition of male sexual characters onto gastropod females), a phenomenon that may cause female sterility and the gastropod populations decline. Despite previous European Union legislation had already been shown effective in reducing the imposex levels along the Portuguese coast, this study intends to confirm these decreasing trends after 2008 and describe the global evolution in the last 15 years. Imposex levels were assessed in two bioindicators - the dog-whelk Nucella lapillus and the netted-whelk Nassarius reticulatus (Gastropoda, Prosobranchia) - in 2011 and 2014, and the results were compared with previous years. Both species showed progressive decreasing trends in imposex levels over the last 15 years; median values of the vas deferens sequence index (VDSI) fell from 3.96 to 0.78 in N. lapillus and from 3.39 to 0.29 in N. reticulatus. The temporal/spatial evolution of imposex suggests an apparent shift of TBT hotspots, being now restricted to fishing ports and marinas in detriment of large commercial harbours where TBT levels fell rapidly. Butyltins were measured in the whole tissues of N. lapillus females collected in 2014: monobutyltin (MBT) varied from < DL (detection limit: 1 ng Sn/g) to 13 ng Sn/g dw, dibutyltin (DBT) from 2.2 to 27 ng Sn/g dw and TBT from 1.5 to 55 ng Sn/g dw. Although TBT body burden has declined over time, the butyltin degradation index ([MBT]+[DBT])/[TBT] exhibited values < 1 in c. a. 90% of the sites assessed, suggesting that recent TBT inputs are still widespread in the Portuguese coast eventually due to illegal use of TBT antifouling systems and TBT desorption from sediments. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Fifteen-year follow-up of smoking prevention effects in the North Karelia youth project.

    Science.gov (United States)

    Vartiainen, E; Paavola, M; McAlister, A; Puska, P

    1998-01-01

    This study evaluated the long-term effects of a school- and community-based smoking prevention program in Finland. Four intervention schools from North Karelia and two control schools from another province were chosen for the evaluation. Students who received the intervention were taught to resist social pressures to smoke. The program began in 1978 with seventh-grade students and ran through 1980, with a 15-year follow-up. In North Karelia, a community-based smoking cessation program for adults was also carried out. Mean lifetime cigarette consumption was 22% lower among program subjects than among control subjects. Smoking and prevalence were lower up to the age of 21. Long-term smoking prevention effects can be achieved if a school-based program using a social influence model is combined with community and mass media interventions.

  12. A critique and comparison of two scales from fifteen years of studying compulsive buying.

    Science.gov (United States)

    Manolis, Chris; Roberts, James A; Kashyap, Vishal

    2008-02-01

    Compulsive buying is an important construct in marketing that has far-reaching personal and social implications. The profile of the adult compulsive buyer in the literature is based largely on the 1992 Faber and O'Guinn Compulsive Buying Scale. A second compulsive buying scale by Edwards has also been used but sparingly. Empirical research conducted over that past 15 years with these two scales shows that, although both scales were designed to measure compulsive buying, the two appear to be different operationalizations of the construct. The present review raises several psychometric issues about both scales. Their robustness is crucial to a clear understanding of the antecedents and consequences of compulsive buying. Directions for research are added.

  13. Fifteen Years of Operation at NASA's National Transonic Facility with the World's Largest Adjustable Speed Drive

    Science.gov (United States)

    Sydnor, George H.; Bhatia, Ram; Krattiger, Hansueli; Mylius, Justus; Schafer, D.

    2012-01-01

    In September 1995, a project was initiated to replace the existing drive line at NASA's most unique transonic wind tunnel, the National Transonic Facility (NTF), with a single 101 MW synchronous motor driven by a Load Commutated Inverter (LCI). This Adjustable Speed Drive (ASD) system also included a custom four-winding transformer, harmonic filter, exciter, switch gear, control system, and feeder cable. The complete system requirements and design details have previously been presented and published [1], as well as the commissioning and acceptance test results [2]. The NTF was returned to service in December 1997 with the new drive system powering the fan. Today, this installation still represents the world s largest horizontal single motor/drive combination. This paper describes some significant events that occurred with the drive system during the first 15 years of service. These noteworthy issues are analyzed and root causes presented. Improvements that have substantially increased the long term viability of the system are given.

  14. Fifteen years of acute flaccid paralysis surveillance in Hong Kong: findings from 1997 to 2011.

    Science.gov (United States)

    2014-07-01

    Acute flaccid paralysis (AFP) surveillance system was set up in Hong Kong in 1997 for World Health Organization's (WHO) certification of poliomyelitis eradication. This paper describes and reviews the demographic, clinical and virological characteristics of AFP cases reported to the system in its first 15 years. All patients aged under 15 years presented with acute onset of paralysis of any limbs reported to the Department of Health from January 1997 to December 2011 were reviewed. Data on demographic characteristics, vaccination history, clinical presentation and virological investigation on stool specimens collected during investigation were analysed with descriptive statistics. Of the 247 cases reported, about 45% were aged under five. All cases were classified as non-polio AFP according to WHO classification. About 60% were identified with neurological disorders, with Guillain-Barré syndrome (25.9%) and myelitis (13.4%) being the most common. Viruses were detected in 14.0% of the AFP cases, with non-polio enteroviruses (NPEV) (60.0%) and adenoviruses (31.4%) accounted for most of the positive detections. Most performance indicators set by the WHO were fulfilled. The AFP surveillance facilitated the clinical, virological and epidemiological examination of paediatric AFP cases. From 1997 to 2011, Guillain-Barré syndrome and myelitis were the most common among paediatric AFP cases in Hong Kong. NPEV and adenoviruses accounted for most of the positive viral detections. No wild poliovirus was detected, and all cases were classified as non-polio AFP. © 2014 The Author. Journal of Paediatrics and Child Health © 2014 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

  15. Buerger’s Disease in Tehran University of Medical Sciences Hospitals: A Fifteen Years Study

    Directory of Open Access Journals (Sweden)

    Salimi Javad

    2009-10-01

    Full Text Available Buerger's disease is an occlusive inflammatory disease of the small and medium-sized arteries and accounts for a variable proportion of patients with peripheral vascular disease throughout the world. The aim of this study was to review the records of Buerger's disease patients admitted to surgery wards of our university hospitals. 277 patients with Buerger's disease were surgically treated between 1987 and 2002, in affiliated hospitals of Tehran University of Medical Sciences, in Iran. Two hundred and seventy three (98.6% of the patients were male, aged 41.5 ± 11 years (mean ± SD; 99.6% of which were smokers with an average of 22.9 pack/years tobacco use. The major complaints included: ischemic ulcers in 203 (73.3%, CI 95%: 0.68-0.77 patients, rest pain in 201 (72.6%, CI 95%: 0.64-0.73, paresthesia in 143 (51.3%, CI 95%: 0.48- 0.58. Vascular bypass, sympathectomy and amputation were performed in 9.7% (CI 95%: 0.08-0.14 and 69.3% (CI 95%: 0.51-0.60 and 59.6% (CI 95%: 0.65-0.73 of the patients, respectively. Lumbar sympathectomy was carried out in 177 (63.9% patients, while 15 (5.4% patients underwent thoracic sympathectomy. In our study, afflicted patients were mostly young males, inveterate tobacco smokers. Patients presented frequently with ischemic ulcers or severe rest pain; thrombophlebitis and Raynaud's phenomenon were infrequent. Vascular reconstruction was rarely possible due to distal and segmental involvement; therefore sympathectomy and amputation were inevitable in a large group of patients in this study.

  16. Fifteen years after parental divorce: mental health and experienced life-events.

    Science.gov (United States)

    Angarne-Lindberg, Teresia; Wadsby, Marie

    2009-01-01

    The children who experienced their parents' divorce when the divorce rate in Sweden had begun to grow to higher levels than in preceding decades are today adults. The aim of this study was to investigate if adults who had experienced parental divorce 15 years before the time of our study, differed in mental health from those with continuously married parents, taking into account life events other than the divorce. Instruments used were the Symptom Checklist (SCL-90) measuring mental health and the Life Event questionnaire capturing the number and experience of occurred events. Forty-eight persons, who were 7-18 years old when their parents divorced, constituted the divorce group, and 48 persons matched on age, sex and growth environment formed the study groups. The SCL-90 showed a limited difference between the groups, but not concerning total mental health. A main finding was a difference with regard to sex and age; women aged 22-27 in the divorce group displayed poorer mental health than other participants in both groups. The results from the Life Event questionnaire showed that the divorce group had experienced a significantly larger number of events, and more life events were described as negative with difficult adjustment. A regression analysis showed a significant relation between the SCL-90, Global Severity Index and life events experienced as negative with difficult adjustment, divorce events excluded, but not with the divorce itself. It seems highly desirable to pay more attention than has thus far been paid to girls with experience of childhood divorce at age 7-12.

  17. Fifteen years of the Protein Crystallography Station: the coming of age of macromolecular neutron crystallography.

    Science.gov (United States)

    Chen, Julian C-H; Unkefer, Clifford J

    2017-01-01

    The Protein Crystallography Station (PCS), located at the Los Alamos Neutron Scattering Center (LANSCE), was the first macromolecular crystallography beamline to be built at a spallation neutron source. Following testing and commissioning, the PCS user program was funded by the Biology and Environmental Research program of the Department of Energy Office of Science (DOE-OBER) for 13 years (2002-2014). The PCS remained the only dedicated macromolecular neutron crystallography station in North America until the construction and commissioning of the MaNDi and IMAGINE instruments at Oak Ridge National Laboratory, which started in 2012. The instrument produced a number of research and technical outcomes that have contributed to the field, clearly demonstrating the power of neutron crystallo-graphy in helping scientists to understand enzyme reaction mechanisms, hydrogen bonding and visualization of H-atom positions, which are critical to nearly all chemical reactions. During this period, neutron crystallography became a technique that increasingly gained traction, and became more integrated into macromolecular crystallography through software developments led by investigators at the PCS. This review highlights the contributions of the PCS to macromolecular neutron crystallography, and gives an overview of the history of neutron crystallography and the development of macromolecular neutron crystallography from the 1960s to the 1990s and onwards through the 2000s.

  18. Is Email Business Dying?: A Study on Evolution of Email Spam Over Fifteen Years

    Directory of Open Access Journals (Sweden)

    De Wang

    2014-05-01

    Full Text Available With the increasing dedication and sophistication of spammers, email spam is a persistent problem even today. Popular social network sites such as Facebook, Twitter, and Google+ are not exempt from email spam as they all interface with email systems. While some report predicts that email spam business is dying due to the decreasing volume of email spam. Whether email spam business is really dying is an interesting question. In this paper, we analyze email spam trends on Spam Archive dataset, which contains 5.5 million spam emails over 15 years (1998 – 2013. We statistically analyze emails contents including header information (e.g. content type and embedded items (e.g. URL links. Also, we investigate topic drift using topic modeling technique. Moreover, we perform network analysis on sender-to-receiver IP routing networks. Our study shows the dynamic nature of email spam over one and a half decades and demonstrate that the email spam business is not dying but more capricious.

  19. Measured and modelled trends in European mountain lakes: results of fifteen years of cooperative studies

    Directory of Open Access Journals (Sweden)

    Michela ROGORA

    2004-02-01

    Full Text Available Papers included in this Special Issue of the Journal of Limnology present results of long-term ecological research on mountain lakes throughout Europe. Most of these studies were performed over the last 15 years in the framework of some EU-funded projects, namely AL:PE 1 and 2, MOLAR and EMERGE. These projects together considered a high number of remote lakes in different areas or lake districts in Europe. Central to the projects was the idea that mountain lakes, while subject to the same chemical and biological processes controlling lowland lakes, are more sensitive to any input from their surroundings and can be used as earlywarning indicators of atmospheric pollution and climate change. A first section of this special issue deal with the results of long-term monitoring programmes at selected key-sites. A second section focuse on site-specific and regional applications of an acidification model designed to reconstruct and predict long-term changes in the chemistry of mountain lakes.

  20. Fifteen-year follow-up of quality of life in type 1 diabetes mellitus.

    Science.gov (United States)

    van Dijk, Peter R; Logtenberg, Susan Jj; Groenier, Klaas H; Keers, Joost C; Bilo, Henk Jg; Kleefstra, Nanne

    2014-08-15

    To evaluate metabolic control and health-related quality of life (HRQOL) in a type 1 diabetes mellitus (T1DM) population. As part of a prospective cohort study, 283 T1DM patients treated with various insulin treatment modalities including multiple daily injections (MDI) and continuous subcutaneous insulin infusion (CSII) were examined annually. HRQOL was measured using the SF-36 and EuroQol questionnaires. Data regarding HRQOL, glycaemic and metabolic control from baseline and follow-up measures in 2002 and 2010 were analysed. Linear mixed models were used to calculate estimated values and differences between the three moments in time and the three treatment modalities. Significant changes [mean Δ (95%CI)] in body mass index [2.4 kg/m(2) (1.0, 3.8)], systolic blood pressure [-6.4 mmHg (-11.4, -1.3)] and EuroQol-VAS [-7.3 (-11.4, -3.3)] were observed over time. In 2010, 168 patients were lost to follow-up. Regarding mode of therapy, 52 patients remained on MDI, 28 remained on CSII, and 33 patients switched from MDI to CSII during follow-up. Among patients on MDI, HRQOL decreased significantly over time: mental component summary [-9.8 (-16.3, -3.2)], physical component summary [-8.6 (-15.3, -1.8)] and EuroQol-VAS [-8.1 (-14.0, -2.3)], P VAS decreased [-9.6 (-17.5, -1.7)]. None of the changes over time in HRQOL differed significantly with the changes over time within the other treatment groups. No differences with respect to metabolic and HRQOL parameters between the various insulin treatment modalities were observed after 15 years of follow-up in T1DM patients.

  1. Vegan-vegetarian low-protein supplemented diets in pregnant CKD patients: fifteen years of experience.

    Science.gov (United States)

    Attini, Rossella; Leone, Filomena; Parisi, Silvia; Fassio, Federica; Capizzi, Irene; Loi, Valentina; Colla, Loredana; Rossetti, Maura; Gerbino, Martina; Maxia, Stefania; Alemanno, Maria Grazia; Minelli, Fosca; Piccoli, Ettore; Versino, Elisabetta; Biolcati, Marilisa; Avagnina, Paolo; Pani, Antonello; Cabiddu, Gianfranca; Todros, Tullia; Piccoli, Giorgina B

    2016-09-20

    Pregnancy in women with advanced CKD becoming increasingly common. However, experience with low-protein diets in CKD patients in pregnancy is still limited. Aim of this study is to review the results obtained over the last 15 years with moderately restricted low-protein diets in pregnant CKD women (combining: CKD stages 3-5, proteinuria: nephrotic at any time, or > =1 g/24 at start or referral; nephrotic in previous pregnancy). CKD patients on unrestricted diets were employed for comparison. January, 2000 to September, 2015: 36 on-diet pregnancies (31 singleton deliveries, 3 twin deliveries, 1 pregnancy termination, 1 miscarriage); 47 controls (42 singleton deliveries, 5 miscarriages). The diet is basically vegan; since occasional milk and yoghurt are allowed, we defined it vegan-vegetarian; protein intake (0.6-0.8 g/Kg/day), keto-acid supplementation, protein-unrestricted meals (1-3/week) are prescribed according to CKD stage and nutritional status. Statistical analysis was performed as implemented on SPSS. Patients and controls were similar (p: ns) at baseline with regard to age (33 vs 33.5), referral week (7 vs 9), kidney function (CKD 3-5: 48.4 % vs 64.3 %); prevalence of hypertension (51.6 % vs 40.5 %) and proteinuria >3 g/24 h (16.1 % vs 12.2 %). There were more diabetic nephropathies in on-diet patients (on diet: 31.0 % vs controls 5.3 %; p 0.007 (Fisher)) while lupus nephropathies were non-significantly higher in controls (on diet: 10.3 % vs controls 23.7 %; p 0.28 (Fisher)). The incidence of preterm delivery was similar (vegan-vegetarian supplemented diet is confirmed as a safe option in the management of pregnant CKD patients.

  2. Chernobyl, fifteen years after

    International Nuclear Information System (INIS)

    2001-04-01

    This work has been constituted around four questions: the future of the Chernobyl site, the damaged reactor, and the sarcophagus around it; the health consequences of the accident on the persons that have worked on the damaged reactor and on the population in the countries the most exposed to fallout,; the situation of contaminated territories around the power plant and their management today; the last question concerns especially the France with the consequences of the radioactive cloud and what we know about the health risks induced by this event. (N.C.)

  3. Ancient earthquakes in the Roman city of Baelo Claudia (Cadiz, South of Spain): Fifteen years of archaeosimology research

    Energy Technology Data Exchange (ETDEWEB)

    Silva, P.G.; Giner-Robles, J.L.; Reicherter, K.; Rodriguez-Pascua, J.L.; Gruetzner, C.; Garcia-Jimenez, I.; Carrasco Garcia, P.; Bardaji, T.; Santos, G.; Roquero, E.; Roez, J.; Perucha, M.A.; Perez-Lopez, R.; Fernandez Macarro, B.; Martinez-Grana, A.; Goy, J.L.; Zazo, C.

    2016-07-01

    This work illustrates the state of the art on archaeoseismology of the ancient Roman city of Baelo Claudia (Tarifa, Cádiz) after nearly fifteen years of research. This ancient Roman site was affected by two earthquakes in the years AD 40–60 and AD 260–290 which promoted important urban and architectural changes and eventually the destruction and further abandonment of the city in AD 365–390. Earthquake Archaeoseismological Effects (EAEs) are catalogued, described and mapped in the entire monumental sector of the city mainly witnessing the last earthquake which occurred in AD 260–290. Mapping of oriented EAEs illustrate damage distribution all over the lower sector of the city, as well as the occurrence of suspect coseismic landslide and tsunami events. The structural analysis of oriented EAEs throughout the entire mapped sector suggests that the intervening ground motion was preferentially oriented in a SW to NE direction. The geoarchaeological analysis and some relevant archaeological anomalies, strongly suggest the occurrence of coeval tsunami events during both ancient earthquakes, pointing to the occurrence of an offshore seismic source SSW of the city. Several N-S normal faults have been identified around the Bolonia Bay area and some of them continue offshore SSW of Baelo Claudia. These faults with clear Quaternary activity can be considered as the more probable seismic sources for the events affecting the ancient Roman site and they are consistent with the mapped damage orientation displayed by the structural analysis of EAEs within the old Roman city. (Author)

  4. Sexual Violence Against Children under Fifteen Years in the Case Lubanga: Critical Analysis and a Proposed Solution

    Directory of Open Access Journals (Sweden)

    Leandro Alberto Dias

    2014-10-01

    Full Text Available One of the most controversial issues that the Pre-Trial Chamber I of the International Criminal Court had to decide in their judgment against Thomas Lubanga Dyilo was the legal treatment of the acts of sexual violence committed during the armed conflict of Ituri. This was a challenging aspect because the Prosecutor had previously decided not to present charges based on sex crimes. On the contrary, he mostly focused his prosecutorial strategy on the war crimes of conscripting, enlisting children under the age of fifteen years or using them to participate actively in hostilities. Facing that situation, the majority of the Trial Chamber I decided not to analyse the issue, while judge Elizabeth Odio Benito took up this point and considered that acts of sexual violence constitute an active participation in hostilities. In this essay I will critically analyse both opinions with the aim of offering an alternative explanation. The latter could be read as follows: despite the fact that acts of sexual violence were not included in the charges, they are covered by the conducts of conscripting or enlisting.

  5. The 22q11.2 microdeletion: fifteen years of insights into the genetic and neural complexity of psychiatric disorders.

    Science.gov (United States)

    Drew, Liam J; Crabtree, Gregg W; Markx, Sander; Stark, Kimberly L; Chaverneff, Florence; Xu, Bin; Mukai, Jun; Fenelon, Karine; Hsu, Pei-Ken; Gogos, Joseph A; Karayiorgou, Maria

    2011-05-01

    Over the last fifteen years it has become established that 22q11.2 deletion syndrome (22q11DS) is a true genetic risk factor for schizophrenia. Carriers of deletions in chromosome 22q11.2 develop schizophrenia at rate of 25-30% and such deletions account for as many as 1-2% of cases of sporadic schizophrenia in the general population. Access to a relatively homogeneous population of individuals that suffer from schizophrenia as the result of a shared etiological factor and the potential to generate etiologically valid mouse models provides an immense opportunity to better understand the pathobiology of this disease. In this review we survey the clinical literature associated with the 22q11.2 microdeletions with a focus on neuroanatomical changes. Then, we highlight results from work modeling this structural mutation in animals. The key biological pathways disrupted by the mutation are discussed and how these changes impact the structure and function of neural circuits is described. Copyright © 2010 ISDN. Published by Elsevier Ltd. All rights reserved.

  6. The First Fifteen Years of Steroid Receptor Research in Zebrafish; Characterization and Functional Analysis of the Receptors

    Directory of Open Access Journals (Sweden)

    Marcel J. M. Schaaf

    2017-07-01

    Full Text Available Steroid hormones regulate a wide range of processes in our body, and their effects are mediated by steroid receptors. In addition to their physiological role, these receptors mediate the effects of endocrine disrupting chemicals (EDCs and are widely used targets for dugs involved in the treatment of numerous diseases, ranging from cancer to inflammatory disorders. Over the last fifteen years, the zebrafish has increasingly been used as an animal model in steroid receptor research. Orthologues of all human steroid receptor genes appear to be present in zebrafish. All zebrafish steroid receptors have been characterized in detail, and their expression patterns have been analyzed. Functional studies have been performed using morpholino knockdown of receptor expression and zebrafish lines carrying mutations in one of their steroid receptor genes. To investigate the activity of the receptors in vivo, specific zebrafish reporter lines have been developed, and transcriptomic studies have been carried out to identify biomarkers for steroid receptor action. In this review, an overview of research on steroid receptors in zebrafish is presented, and it is concluded that further exploitation of the possibilities of the zebrafish model system will contribute significantly to the advancement of steroid receptor research in the next decade.

  7. Australia's Ongoing Legacy of Asbestos: Significant Challenges Remain Even after the Complete Banning of Asbestos Almost Fifteen Years Ago.

    Science.gov (United States)

    Soeberg, Matthew; Vallance, Deborah A; Keena, Victoria; Takahashi, Ken; Leigh, James

    2018-02-23

    The most effective way of reducing the global burden of asbestos-related diseases is through the implementation of asbestos bans and minimising occupational and non-occupational exposure to respirable asbestos fibres. Australia's asbestos consumption peaked in the 1970s with Australia widely thought to have had among the highest per-capita asbestos consumption level of any country. Australia's discontinuation of all forms of asbestos and asbestos-containing products and materials did not occur at a single point of time. Crocidolite consumption ceased in the late 1960s, followed by amosite consumption stopping in the mid 1980s. Despite significant government reports being published in 1990 and 1999, it was not until the end of 2003 that a complete ban on all forms of asbestos (crocidolite, amosite, and chrysotile) was introduced in Australia. The sustained efforts of trade unions and non-governmental organisations were essential in forcing the Australian government to finally implement the 2003 asbestos ban. Trade unions and non-government organisations continue to play a key role today in monitoring the government's response to Australian asbestos-related disease epidemic. There are significant challenges that remain in Australia, despite a complete asbestos ban being implemented almost fifteen years ago. The Australian epidemic of asbestos-related disease has only now reached its peak. A total of 16,679 people were newly diagnosed with malignant mesothelioma between 1982 and 2016, with 84% of cases occurring in men. There has been a stabilisation of the age-standardised malignant mesothelioma incidence rate in the last 10 years. In 2016, the incidence rate per 100,000 was 2.5 using the Australian standard population and 1.3 using the Segi world standard population. Despite Australia's complete asbestos ban being in place since 2003, public health efforts must continue to focus on preventing the devastating effects of avoidable asbestos-related diseases, including

  8. Development and use of a fifteen year-old equivalent mathematical phantom for internal dose calculations. [Radiation dose distributions from /sup 99m/Tc-labeled compounds

    Energy Technology Data Exchange (ETDEWEB)

    Jones, R.M.; Poston, J.W.; Hwang, J.L.; Jones, T.D.; Warner, G.G.

    1976-06-01

    The existence of a phantom based on anatomical data for the average fifteen-year-old provides for a proficient means of obtaining estimates of absorbed dose for children of that age. Dimensions representative of an average fifteen-year-old human, obtained from various biological and medical research, were transformed into a mathematical construct of idealized shapes of the exterior, skeletal system, and internal organs of a human. The idealization for an average adult presently in use by the International Commission on Radiological Protection was used as a basis for design. The mathematical equations describing the phantom were developed to be readily adaptable to present-day methods of dose estimation. Typical exposure situations in nuclear medicine have previously been modeled for existing phantoms. With no further development of the exposure model necessary, adaptation to the fifteen-year-old phantom demonstrated the utility of the design. Estimates of absorbed dose were obtained for the administration of two radiopharmaceuticals, /sup 99m/Tc-sulfur colloid and /sup 99m/Tc-DMSA. (auth)

  9. One the way to European Union: changes in the Czech education system during the last fifteen years

    Directory of Open Access Journals (Sweden)

    Milada Rubusicová

    2004-01-01

    Full Text Available The aim of the present paper is to describe the changes in the educationalsystem in the Czech Republic that have taken place from the beginning of the 1990’s up to the present. The first part includes a brief characterisation of the initial situation typical of the socialist model of education and a specification ofthose areas that were viewed sceptically or critically after the „velvet revolution»in 1989, and that have been identified as areas where a change is desirable. Next part of the paper describes the course of changes and reforms of education in subsequent years. Periodisation of reforms is carried out on the basisof a general model that has been created, as one of possible approaches, for postsocialist countries in transformation. Each part of the model, i.e. the correctivereforms, modernization reforms, structural reforms and system reforms, containsan outline of the respective individual changes that took place in the Czech Republic in the course of the last, almost fifteen years, and the changes arecritically evaluated.There are some documents (e.g. the Czech «White Paper» that are of essential importance to the recent and current situation in the Czech educational systembecause they create basic visions and orientation but also a strategy of future changes. The documents are treated in the next section of the present text. It isfollowed by a brief analysis of the current situation of the Czech educational system, namely as regards the educational opportunities and participation in education, structure and network of schools, financing of the Czech educational system, and finally the school leavers’ prospects at the labour market.The last part of the paper deals with the outlooks of further development of the Czech educational system in connection with the entry into the European Union,and a conclusion is drawn that it involves mutual convergence of problems caused by global economic and social forces that also leads to

  10. Fifteen-Year Prospective Analysis of Television Viewing and Adiposity in African American and Caucasian Men and Women

    Directory of Open Access Journals (Sweden)

    Chung-Yu Chen

    2015-08-01

    Full Text Available There are limited data from long-term prospective studies on the association between television (TV viewing and obesity. We investigated this association between TV viewing and body mass index (BMI and waist circumference (WST over 15 years on 3,269 participants from the Coronary Artery Risk Development in Young Adults (CARDIA study. We used cross-lagged panel models at exam Years 5, 10, 15, and 20 over 15 years to assess the association between TV viewing and obesity. The cross-lagged effects of TV viewing on anthropometry were significant from exam Year 5 to Year 10 (B = 0.034 for BMI and 0.036 for WST. However, the cross-lagged effects of TV viewing at Years 10 and 15 on obesity at Years 15 and 20, respectively, were nonsignificant. The findings indicate that higher levels of TV viewing predicted higher BMI and WC in young adulthood, but this association was not observed as individuals aged over the following decade.

  11. Impact of Acceptance and Commitment Therapy on Perceived Stress and Special Health Self-Efficacy in Seven to Fifteen-Year-Old Children With Diabetes Mellitus.

    Science.gov (United States)

    Moazzezi, Mousa; Ataie Moghanloo, Vahid; Ataie Moghanloo, Roghayeh; Pishvaei, Malihe

    2015-06-01

    Diabetes Mellitus (DM) imposes restrictions on physical, emotional and social functioning of children and adolescents. The aim of this study was to determine the impact of acceptance and commitment therapy (ACT) on perceived stress and special health self-efficacy in seven to fifteen-year-old children with DM. The present study was a clinical trial with a pretest-posttest control group design. The study population included all seven to fifteen-year-old patients who had referred to the Diabetes Mellitus Association of Tabriz, Iran, of whom 40 participants were selected using convenient sampling. They were randomly allocated to two matched groups (experimental and control). The experimental group participated in therapy sessions, while the control group did not receive any interventions. The research instruments were perceived stress and special health self-efficacy scales. The multiple analysis of covariance (MANCOVA) results showed that the treatment was effective on variables of perceived stress and special health self-efficacy (P self-efficacy in children with DM.

  12. Total hip replacement fifteen years after pelvic support osteotomy (PSO): a case report and review of the literature.

    Science.gov (United States)

    Thabet, Ahmed M; Catagni, Maurizio A; Guerreschi, Francessco

    2012-08-01

    Treatment of chronic hip instability in children and young adults is challenging. Proximal femoral osteotomy had been suggested to provide pelvic stability and improved abductor function. Total hip replacement after pelvic support osteotomy can be challenging due to altered anatomy due to angulation of the proximal femur in both frontal and sagittal planes. This is a 29-year-old woman who had total hip replacement after pelvic support osteotomy. The patient had pelvic support at the age of 14 years. Pelvic support osteotomy delayed the need for total hip replacement for 15 years. Preoperative planning for total hip replacement with model was used for proper understanding of the anatomy of the proximal femur. Revision of femoral component was necessary due to penetration of the proximal femur. In conclusion, total hip replacement after pelvic support osteotomy is a technically demanding procedure, and careful attention to surgical details is necessary for successful outcome.

  13. Chinese and world equity markets : A review of the volatilities and correlations in the first fifteen years

    NARCIS (Netherlands)

    Lin, Kuan Pin; Menkveld, Albert J.; Yang, Zhishu

    2009-01-01

    After more than 15 years of Chinese equity markets, we study how variance, covariance, and correlations have developed in these markets relative to world markets, based on the dynamic conditional correlation (DCC) model of Engle [Engle, R., 2002. A dynamic conditional correlation: A simple class of

  14. An Atypical Eating Disorder with Crohn's Disease in a Fifteen-Year-Old Male: A Case Study.

    Science.gov (United States)

    Holaday, Margot; And Others

    1994-01-01

    Discusses how 6 months after psychological intervention for an eating disorder, a 15-year-old male was diagnosed with Crohn's disease, a chronic inflammatory bowel disease. Addresses need for additional training for those from traditional school and counseling psychology programs. Advocates a team approach and consultations. (RJM)

  15. Pauci-Immune Necrotizing and Crescentic Glomerulonephritis with Membranous Lupus Nephritis, Fifteen Years after Initial Diagnosis of Secondary Membranous Nephropathy

    Directory of Open Access Journals (Sweden)

    Ryan Burkhart

    2015-01-01

    Full Text Available Renal involvement in systemic lupus erythematosus (SLE is usually immune complex mediated and may have multiple different presentations. Pauci-immune necrotizing and crescentic glomerulonephritis (NCGN refers to extensive glomerular inflammation with few or no immune deposits that may result in rapid decline in renal function. We report a case of a 79-year-old Hispanic male with a history of secondary membranous nephropathy (diagnosed by renal biopsy 15 years previously who was admitted with acute kidney injury and active urinary sediment. P-ANCA titers and anti-myeloperoxidase antibodies were positive. The renal biopsy was diagnostic for NCGN superimposed on a secondary membranous nephropathy. A previous diagnosis of SLE based on American College of Rheumatology criteria was discovered via Veteran’s Administration records review after the completion of treatment for pauci-immune NCGN. ANCAs are detected in 20–31% of patients with SLE. There may be an association between SLE and ANCA seropositivity. In patients with lupus nephritis and biopsy findings of necrotizing and crescentic glomerulonephritis, without significant immune complex deposition, ANCA testing should be performed. In patients with secondary membranous nephropathy SLE should be excluded.

  16. Fifteen-year effects of Helicobacter pylori, garlic, and vitamin treatments on gastric cancer incidence and mortality.

    Science.gov (United States)

    Ma, Jun-Ling; Zhang, Lian; Brown, Linda M; Li, Ji-You; Shen, Lin; Pan, Kai-Feng; Liu, Wei-Dong; Hu, Yuanreng; Han, Zhong-Xiang; Crystal-Mansour, Susan; Pee, David; Blot, William J; Fraumeni, Joseph F; You, Wei-Cheng; Gail, Mitchell H

    2012-03-21

    In the Shandong Intervention Trial, 2 weeks of antibiotic treatment for Helicobacter pylori reduced the prevalence of precancerous gastric lesions, whereas 7.3 years of oral supplementation with garlic extract and oil (garlic treatment) or vitamin C, vitamin E, and selenium (vitamin treatment) did not. Here we report 14.7-year follow-up for gastric cancer incidence and cause-specific mortality among 3365 randomly assigned subjects in this masked factorial placebo-controlled trial. Conditional logistic regression was used to estimate the odds of gastric cancer incidence, and the Cox proportional hazards model was used to estimate the relative hazard of cause-specific mortality. All statistical tests were two-sided. Gastric cancer was diagnosed in 3.0% of subjects who received H pylori treatment and in 4.6% of those who received placebo (odds ratio = 0.61, 95% confidence interval = 0.38 to 0.96, P = .032). Gastric cancer deaths occurred among 1.5% of subjects assigned H pylori treatment and among 2.1% of those assigned placebo (hazard ratio [HR] of death = 0.67, 95% CI = 0.36 to 1.28). Garlic and vitamin treatments were associated with non-statistically significant reductions in gastric cancer incidence and mortality. Vitamin treatment was associated with statistically significantly fewer deaths from gastric or esophageal cancer, a secondary endpoint (HR = 0.51, 95% CI = 0.30 to 0.87; P = .014).

  17. Adrenal Incidentaloma Diagnosed as a Pheochromocytoma in a fifteen-year-old Dog - An Unexpected Finding with Deadly Consequences

    Directory of Open Access Journals (Sweden)

    R Seixas and AM Alho*

    2013-11-01

    Full Text Available Adrenal incidentalomas are masses of the adrenal gland discovered inadvertently during diagnostic procedures, from which a significant percentage are pheochromocytomas and these tumors are rare. Here we report a case of a 15-year-old male dog whose main complaints were a soft cervical mass and mild generalized weakness. Blood cell count, routine biochemistry, arterial blood pressure and electrocardiogram were performed. Diagnostic imaging revealed a 3.5 cm mass next to the right adrenal gland. Surgery was performed and histopathology examination of the mass confirmed a malignant pheochromocytoma. The dog died 96 hours later after surgery. At necropsy, metastasis was found in cervical lymph node. Considering vague and episodic clinical signs, pheochromocytoma antemortem diagnosis is uncommon. The main aim of this case is to highlight this endocrinology disorder, increasing the awareness of clinicians to this difficult diagnostic condition.

  18. Fifteen years of follow-up of a liver transplant recipient with glycogen storage disease type Ia (Von Gierke disease).

    Science.gov (United States)

    Maya Aparicio, A C; Bernal Bellido, C; Tinoco González, J; Garcia Ruíz, S; Aguilar Romero, L; Marín Gómez, L M; Suárez Artacho, G; Alamo Martínez, J M; Serrano Díez-Canedo, J; Padillo Ruíz, F J; Gomez Bravo, M A

    2013-01-01

    Von Gierke's disease or glycogen storage disease type Ia (GSD-Ia) is an infrequent metabolic disease caused by an atypical accumulation of glycogen. The principal cause of this pathology is deficiency of the glucose-6-phosphatase enzyme. Herein we have reported a case of a young man with a history of Von Gierke's disease (GSD-Ia) since childhood who developed hepatocellular adenomatosis brought to light by ultrasounds and TACs. The patient began to develop early chronic renal failure, necessitating simultaneous liver and kidney transplantation. Years later continuous reviews at the nephrology and hepatobiliopancreatic surgery services show he has a good quality of life and a normal hepatorenal profile. Copyright © 2013 Elsevier Inc. All rights reserved.

  19. Fifteen years of successful spread of Salmonella enterica serovar Mbandaka clone ST413 in Poland and its public health consequences

    Directory of Open Access Journals (Sweden)

    Andrzej Hoszowski

    2016-06-01

    Full Text Available In the 1990s, [i]Salmonella enterica[/i] serovar (S. Mbandaka occurred in feed and poultry in Poland. In the following years, the serovar also gained epidemiological importance in other EU countries. The objectives of current study were to evaluate the genetic relationship of contemporary S. Mbandaka with isolates originating from the beginning of the epidemics, and to assess the contribution of poultry as the source of infections in humans. Seventy S. Mbandaka isolated mainly in 2009 – 2010 from humans, poultry, food, and feed were typed with API ID32 [sup]®[/sup], MIC, plasmid profiling, PFGE, and MLST. PCR and sequencing were used to identify plasmid mediated quinolone and cephalosporin resistance mechanisms. Six biochemical profiles were identified and 59 of S. Mbandaka proved to be susceptible to the applied antimicrobials. Eight strains carried plasmids and a few of them were positive for [i]bla[/i][sub]CMY-2[/sub] and [i]qnr[/i]S1 genes. Two clusters of 15 [i]XbaI[/i]-PFGE profiles with similarity of 77.5% were found. The first cluster, gathered 7 profiles involving historical isolates and several contemporary non-human S. Mbandaka. The predominant profile in the second cluster consisted of 28 human and 1 broiler isolate. MLST analysis showed sequence type ST413 occurring among all tested isolates. The identification of close genetic relationships between S. Mbandaka of human and poultry origin indicates animals as a primal human infection route. Despite [i]Salmonella [/i]control programmes, the S. Mbandaka ST413 clone has been circulating for several years in Poland. [i]Salmonella[/i] control polices in food production chain should be continuously updated to target serovars of major epidemiological importance. Resistance noted in S. Mbandaka to such antimicrobials as fluoroquinolones and cephalosporins may hinder public health.

  20. From chickpeas to oil. The keys to fifteen years of hispanic-mexican economic relations (1977-1992

    Directory of Open Access Journals (Sweden)

    Santiago Forcada

    1993-07-01

    Full Text Available This article intends to analyse the evolution of economic relations between Spain and Mexico from the reestablishment of diplomatic relations taking into account both the keys to this evolution and its changes. The authors highlight three distinct periods : a boom between 1977 and 1981 ; a relapse between 1982 and 1986 and a recovery between 1987 and 1992. This division into periods takes note of an initial spectacular increase in which bilateral exchanges were multiplied up to 33 times. A five year period in which oil replaced chickpeas as the main product bought in Mexico (up to four-fifths of the total volume and in which Spanish exports multiplied themselves ten times over. Already from this first phase, the commercial balance was clearly in favour of Mexico, a fact more striking during the second period, during which Spanish imports fell up to 50% but whileher exports were reduced by two-thirds. The key was the fall in the price of oil. The continuity of Spanish oil buying in Mexico however precipitated the recovery of the third period which coincided with the signing of the General Friendship and Cooperation Agreement between both countries. In 1992 Spain regained second place as a customer of Mexico behind the United States while the joint political policies coincide in pointing out that these are two reciprocal pathways to both the EC and US markets. The authors however, sustain that the global evolution of economic blocks does not favour this vision bearing in mind that the composition of and leadership in trade between such blocks will be governed, basically, by the strategies deployed by transnational companies.

  1. Tres lustros del periodismo digital:interactividad e hipertextualidad Fifteen Years of Online Journalism. Interaction and Hypertextuality

    Directory of Open Access Journals (Sweden)

    Lizy Navarro Zamora

    2009-10-01

    Full Text Available En el 2009 se cumplen 15 años del inicio del periodismo en Internet. Las características del periodismo han evolucionado con la convergencia digital. La interactividad e hipertextualidad son dos elementos que configuran la esencia de la relación entre periodismo y tecnologías de la información y comunicación. En esta investigación se realizó el análisis del perfil y elementos del periodismo digital, así como el emisor y receptor de este proceso comunicativo. El corpus de la investigación fueron diez medios internacionales y los siguientes medios nacionales: 100 periódicos, 30 cadenas de televisión y 30 emisoras de radio que desde hace más de 10 años están en Internet. También se realizó el envío de 2.000 correos electrónicos a un corpus de otros tantos periodistas: reporteros, editorialistas y webmaster. On-line journalism completes 15 years of existence in 2009. The characteristics of journalism have evolved with information technology. Interaction and hypertextuality are two elements that configure the essence of the relationship between journalism and new information and communication technologies. This research analyzes the profile and elements of on-line journalism, as well as the transmitter and receiver in this communication process. The research corpus is 10 international media and the following Mexican media: 100 newspapers, 30 television stations and 30 radio stations, all with more than 10 years’ on-line experience. Also, two hundred e-mails were sent out to journalists, leader writers and webmasters.

  2. Introduction

    NARCIS (Netherlands)

    Binsbergen, van W.M.J.

    2003-01-01

    This volume brings together fifteen essays investigating aspects of interculturality. Published between 1969 and 2002, the essays operate at the borderline between anthropology and intercultural philosophy. Ethnographic data are derived from field research carried out in Tunisia, Zambia and

  3. Introduction

    Directory of Open Access Journals (Sweden)

    Deborah Hauptmann

    2014-08-01

    Full Text Available Over the past fifteen years most advanced education programmes within Schools of Architecture have been questioning the parameters and requirements of doctoral research both in terms of content and form. This double issue of Footprint was motivated by the question of where the field stands today. Footprint 10|11 presents nine contributions from both recently defended and developing PhD candidates from a variety of institutions. The diversity of their work, as well as the similarities found in the submissions, offers a partial view into research topics currently addressed in PhD programmes within Schools of Architecture. In addition to the nine papers by PhD researchers, we have included a paper by Andrew Leach that we believe provides an overview of the general state of contemporary architecture research. Leach makes an appeal to refrain from making all research operational. At a time when the application of research and its economic value seem to form the primary criteria for judging value, this appeal should not be taken lightly.

  4. Introduction

    Directory of Open Access Journals (Sweden)

    David Harris

    1990-11-01

    Full Text Available Since its foundation as an independent Institute within the University of London fifty-three years ago, the Institute of Archaeology has contributed to research in many aspects of the developing discipline in many different parts of the world. For the first thirty years of its existence it was exclusively a postgraduate research institution, and it has continued to give high priority to postgraduate studies since the introduction of undergraduate teaching in 1968. Today, one third of the 300 students enrolled at the Institute are postgraduates, over 50 of whom are research students registered for MPhil/PhD degrees. Most of the MA and MSc students also undertake their own research projects as part of the Master's degree. Institute postgraduates are thus involved in a multitude of diverse investigations, in Britain, continental Europe, Asia, Africa, Australasia and the Americas, and each year they make, collectively, a very substantial contribution to archaeological knowledge.

  5. Prevalence and contributing factors to attention deficit hyperactivity disorder: A study of five- to fifteen-year-old children in Zhabei District, Shanghai

    OpenAIRE

    Jin, Wenlan; Du, Yasong; Zhong, Xiangyang; David, Coghill

    2013-01-01

    Introduction This work aims to understand the features among 5- to 15-year-old children with attention deficit hyperactivity disorder (ADHD) in Zhabei District in Shanghai. Methods Children with ADHD were studied using general background questionnaire, ADHD symptom rating questionnaire, and cluster-stratified sampling. A total of 9,900 valid questionnaires were utilized in this study. We conducted diagnostic interviews with suspected ADHD children and their parents using the criteria of the D...

  6. Proximal femoral allografts for reconstruction of bone stock in revision arthroplasty of the hip. A nine to fifteen-year follow-up.

    Science.gov (United States)

    Blackley, H R; Davis, A M; Hutchison, C R; Gross, A E

    2001-03-01

    Revision of a femoral component in a patient who has severe bone loss is a complex problem that is likely to increase with the increasing numbers of patients who have multiple revision hip arthroplasties. A valuable option in such a situation is use of a long-stem prosthesis that is cemented to a proximal femoral allograft but not to the host bone. Between April 1984 and December 1989, sixty-three total hip arthroplasties in sixty consecutive patients were revised with a proximal femoral allograft-prosthesis construct. The average length of the allograft was 15 cm. The average age of the patients at the time of the revision was 62.5 years. All patients had undergone at least one previous total hip arthroplasty, and an average of 3.8 previous total hip arthroplasties had been performed in the series. Each patient was assigned a modified Harris hip score. Radiographs were examined for trochanteric union, allograft-host union, endosteal and periosteal resorption, component loosening, and fracture. At an average of eleven years (range, nine years and four months to fifteen years) after the revision, forty-five patients were alive, fourteen patients had died, and one patient had been lost to follow-up. The patients who had died or had been lost to follow-up had had a total of fifteen allografts (24%) and had been followed for an average of five years and seven months (range, two years and four months to eight years). The average preoperative Harris hip score for the sixty-three hips was 30 points (range, 6 to 65 points). At the latest follow-up evaluation, the average score for the hips with the original graft in situ was 71 points (range, 47 to 95 points). Five hips failed because of infection, and four of them were successfully revised. Three hips failed because of aseptic loosening, at an average of ten years and three months; two were successfully revised, and the third was awaiting revision at the time of writing. An additional operation was performed in three hips

  7. Introduction

    DEFF Research Database (Denmark)

    Kørnøv, Lone; Lund, Henrik; Remmen, Arne

    2004-01-01

    The chapter gives an introduction to the book "Environmental planning and management : tools for a sustainable development".......The chapter gives an introduction to the book "Environmental planning and management : tools for a sustainable development"....

  8. Introduction

    DEFF Research Database (Denmark)

    Klitgård, Ebbe; Bayer, Gerd

    2011-01-01

    An introduction to "Narrative Developments from Chaucer to Defoe", including a review of recent research in the field.......An introduction to "Narrative Developments from Chaucer to Defoe", including a review of recent research in the field....

  9. Introduction

    DEFF Research Database (Denmark)

    Høgfeldt Hansen, Leif

    2016-01-01

    This introduction to South Korean architecture gives an overall view of the architecture done in the country in historic times as well as a general introduction to the culture of the country.......This introduction to South Korean architecture gives an overall view of the architecture done in the country in historic times as well as a general introduction to the culture of the country....

  10. Introduction

    DEFF Research Database (Denmark)

    Schmidt, Johannes Dragsbæk; Berg, Torsten Rødel

    2012-01-01

    The chapter includes a discussion about the play by Henrik Ibsen from 1879, A Doll's House, how it still proves to be relevant today to gender relations not only in Denmark but in Nepal as well. The introduction explains how Ibsen's play inspired two theater directors from Denmark and Nepal......, respectively to use it as point of departure for the creation of a trans-civilizational and intercultural dialogue. The intention of this chapter is to introduce the background of the collection of chapters, give broader perspectives about globalization and social change linked with debates about changing...... values and cultures in development and social policy and then enters the specific context and development trajectory in Nepal in recent years....

  11. Fifteen-year trends in the management of cardiogenic shock and associated 1-year mortality in elderly patients with acute myocardial infarction: the FAST-MI programme.

    Science.gov (United States)

    Aissaoui, Nadia; Puymirat, Etienne; Juilliere, Yves; Jourdain, Patrick; Blanchard, Didier; Schiele, François; Guéret, Pascal; Popovic, Batric; Ferrieres, Jean; Simon, Tabassome; Danchin, Nicolas

    2016-09-01

    Alhough cardiogenic shock (CS) after acute myocardial infarction (AMI) is more common in elderly patients, information on the epidemiology of these patients is scarce. This study aimed to assess the trends in prevalence, characteristics, management, and outcomes of elderly patients admitted with CS complicating AMI between 1995 and 2010, using data from the FAST-MI programme. We analysed the incidence and 1-year mortality of CS in four nationwide French surveys carried out 5 years apart from 1995 to 2010, including consecutive AMI patients over 1-month periods. Among the 10 610 patients, 3389 were aged ≥75 years, of whom 9.9% developed CS. The prevalence of CS decreased in elderly patients from 11.6% in 1995 to 6.7% in 2010 (P = 0.02). Over the 15-year period, the characteristics of elderly patients with CS changed, with more diabetes, hypertension, and hypercholesterolaemia. The use of PCI increased markedly in elderly patients with and without CS, reaching 51% and 59%, respectively, in 2010. In addition, medical therapy also evolved, with more patients receiving antithrombotic agents, beta-blockers, and statins. Over time, 1-year mortality decreased by 32% among elderly patients with CS but remained high (59% in 2010). ST-segmet elevation myocardial infarction and previous AMI were independent correlates of increased 1-year death, while study period was associated with decreased mortality (2010 vs, 1995: hazard ratio 0.40, 95% confidence interval 0.27-0.61, P shock in elderly patients with AMI remains a major clinical concern. However, 1-year mortality declined in these patients, a decrease potentially mediated by broader use of PCI and the improvement of global patient management. © 2016 The Authors. European Journal of Heart Failure © 2016 European Society of Cardiology.

  12. Australia’s Ongoing Legacy of Asbestos: Significant Challenges Remain Even after the Complete Banning of Asbestos Almost Fifteen Years Ago

    Science.gov (United States)

    Soeberg, Matthew; Vallance, Deborah A.; Keena, Victoria

    2018-01-01

    The most effective way of reducing the global burden of asbestos-related diseases is through the implementation of asbestos bans and minimising occupational and non-occupational exposure to respirable asbestos fibres. Australia’s asbestos consumption peaked in the 1970s with Australia widely thought to have had among the highest per-capita asbestos consumption level of any country. Australia’s discontinuation of all forms of asbestos and asbestos-containing products and materials did not occur at a single point of time. Crocidolite consumption ceased in the late 1960s, followed by amosite consumption stopping in the mid 1980s. Despite significant government reports being published in 1990 and 1999, it was not until the end of 2003 that a complete ban on all forms of asbestos (crocidolite, amosite, and chrysotile) was introduced in Australia. The sustained efforts of trade unions and non-governmental organisations were essential in forcing the Australian government to finally implement the 2003 asbestos ban. Trade unions and non-government organisations continue to play a key role today in monitoring the government’s response to Australian asbestos-related disease epidemic. There are significant challenges that remain in Australia, despite a complete asbestos ban being implemented almost fifteen years ago. The Australian epidemic of asbestos-related disease has only now reached its peak. A total of 16,679 people were newly diagnosed with malignant mesothelioma between 1982 and 2016, with 84% of cases occurring in men. There has been a stabilisation of the age-standardised malignant mesothelioma incidence rate in the last 10 years. In 2016, the incidence rate per 100,000 was 2.5 using the Australian standard population and 1.3 using the Segi world standard population. Despite Australia’s complete asbestos ban being in place since 2003, public health efforts must continue to focus on preventing the devastating effects of avoidable asbestos-related diseases

  13. Long term monitoring at Solfatara of Pozzuoli (Campi Flegrei, Italy): 1998-2014, fifteen years of soil CO2 flux measurement.

    Science.gov (United States)

    Cardellini, Carlo; Chiodini, Giovanni; Rosiello, Angelo; Bagnato, Emanuela; Avino, Rosario; Frondini, Francesco; Donnini, Marco; Caliro, Stefano

    2015-04-01

    With a flux of deeply derived fluids of ~5000 t/d and an energetic release of ~100 MW Solfatara of Pozzuoli is one of the largest studied volcanic-hydrothermal system of the world. Since 1998, soil CO2 flux surveys where performed using the accumulation chamber method over a large area (1.45 km2), including the volcanic apparatus and its surroundings. The statistical elaboration of CO2 flux, also coupled with the investigation of the CO2 efflux isotopic composition, allowed to characterize both the CO2 flux connected to by biological activity in the soil and that feed to the degassing of the hydrothermal system. A geostatistical elaboration of CO2 fluxes based on sequential Gaussian simulations, allowed to define the spatial structure of the degassing area, pointing out the presence of a well defined diffuse degassing structure interested by the release of deeply derived CO2 (Solfatara DDS). Solfatara DDS results well correlated to volcanic and tectonic structures interesting the crater area and the eastern area of Pisciarelli. With the same approach the total amount of CO2 release was estimated to range between 754 t/d and 1530 t/d in the last fifteen year (with an error in the estimate varying between 9 and 15 %). Also the extension of the DDS experienced relevant variations varying between 4.5x105 m2 to 12.3 x105 m2. In particular two major changes occurred in the extension of the DDS, the first consisted in its doubling in 2003-2004 and the second in further enlargement of ~ 30% in 2011-2012, the last occurring after period of decreasing trend which interrupted 4-5 years of relative stability. These variations mainly occurred external to the crater area in correspondence of a NE-SW fault system where fluxes increased from background to values typical of the endogenous source. The first event was previously correlated with the occurrence in 2000 of a relatively deep seismic swarm, which was interpreted as the indicator of the opening of an easy-ascent pathway

  14. Changes in educational inequalities in Poland. Comments on Zbigniew Sawiński’s article “Education reform and inequality: fifteen years of new lower secondary schools in Poland”

    Directory of Open Access Journals (Sweden)

    MICHAŁ SITEK

    2017-06-01

    Full Text Available In his text published in Edukacja, 141(2, 2017 („Education reform and inequality: fifteen years of new lower secondary schools in Poland”, Zbigniew Sawiński analyses data from the 2000 to 2012 editions of the OECD PISA study and argues that lower secondary school reform has not reduced educational inequalities in Poland. The importance of students’ social origin remained at the same level as before the reform, the impact of social origin on the choice of type of secondary school remained the same, and an increasing differentiation of lower secondary schools did not lead to an increase in educational inequalities. I present methodological arguments and the results of a re-analysis of PISA data, indicating changes in wider educational inequalities. Between 2000 and 2012: (a the strength of association in the performance of 15-year-olds with the socio-economic status of students’ families did not change, but (b the variation of results decreased, which was mainly due to the improved performance of the lowest performing students, (c the differences between students of high and low socio-economic status decreased, (d the influence of social origin on the choice of the type of upper secondary school decreased. The effects of socio-economic status on upper secondary school choice is largely direct: it is not mediated by the educational achievements of students. The commentary also highlights the complexity of lower secondary school reform, which was not limited to the introduction of such schools. I indicate the role of factors that make it difficult to interpret the results of the reform in causal terms – particularly the role of unobserved variables related to the changes in the learning environments of subsequent cohorts of students.

  15. Introduction

    DEFF Research Database (Denmark)

    Søbjerg, Lene Mosegaard

    2016-01-01

    Introduction to anthology which provides the theoretical basis of an Erasmus+ project involving marginalised young people, practitioners, students and academics in co-creating a teaching module for the social professions....

  16. Introduction

    DEFF Research Database (Denmark)

    Henkel, Anna; Åkerstrøm Andersen, Niels

    2015-01-01

    An introduction is presented in which the authors discuss various reports within the issue on topics including the concept of responsibility, the discourse about responsibility, and the attribution of responsibility in an interdisciplinary context.......An introduction is presented in which the authors discuss various reports within the issue on topics including the concept of responsibility, the discourse about responsibility, and the attribution of responsibility in an interdisciplinary context....

  17. A questão racial na política brasileira (os últimos quinze anos The racial question in Brazilian politics (the past fifteen years

    Directory of Open Access Journals (Sweden)

    Antonio Sérgio Alfredo Guimarães

    2001-11-01

    Full Text Available Neste artigo, analiso o modo como a questão racial tem marcado a política brasileira nos últimos quinze anos. Começo expondo o que significou a idéia de democracia racial no processo de construção da nacionalidade brasileira, para depois, com a brevidade que o espaço exige, resenhar os estudos sobre o comportamento eleitoral dos negros brasileiros e tratar da emergência de movimentos sociais negros e de sua incorporação ao sistema político. Meu entendimento é que devemos ver na "democracia racial" um compromisso político e social do moderno estado republicano brasileiro, que vigeu, alternando força e convencimento, do Estado Novo de Vargas até o final da ditadura militar. Tal compromisso, hoje em crise, consistiu na incorporação da população negra brasileira ao mercado de trabalho, na ampliação da educação formal, enfim na criação das condições infra-estruturais de uma sociedade de classes que desfizesse os estigmas criados pela escravidão. A imagem do negro enquanto povo comum e o banimento, no pensamento social brasileiro, do conceito de "raça", substituído pelos de "cultura" e "classe social", são as expressões maiores desse compromisso.In this article, I analyze how the racial question has marked Brazilian politics in the past fifteen years. I start by showing what the idea of racial democracy meant to the process of reconstruction of the Brazilian nationality, and go on to review the studies on the voting behaviour of the Brazilian Black population and discuss the emergence of Black social movements and their incorporation into the political system. I understand that we must see "racial democracy" as a political and social compromise of the Brazilian modern republican state, which was in power from the Vargas' New State until the end of the military dictatorship. This compromise which at present is in crisis, consisted of the incorporation of the Brazilian Black population into the work market, of the

  18. Introduction

    International Nuclear Information System (INIS)

    Ainul Hayati Daud; Hazmimi Kasim

    2010-01-01

    Since the Atoms for Peace program in 1950s, peaceful applications of nuclear technology has been at the forefront of the development of many countries. In Malaysia, the development of nuclear technology began in earnest with the setting-up of Malaysian Nuclear Agency (Nuclear Malaysia) in 1972, then known as CRANE. More than thirty years later, today, the technology has gained footing and made impact to the development of the country. Her role in regional and international scenes in nuclear-related matters and nuclear technology was noticed and being given due attention. It is time to take stock of this development and assess its impact upon which further developments can be planned and strategized. That was the genesis of this study. This chapter presents a review of the status and development of nuclear technology globally and in Malaysia to provide a background for the report and the study. This is followed by an introduction to the study: its objectives, scope, methods of research, total population, sampling frame, selection procedures, target groups and data analysis. The chapter concludes with a guide to the organization of this report. The study was conducted with the aim of evaluating the impact and contribution of nuclear technology to socio-economic development of the country. It is also expected to identify issues and challenges faced by users of this technology. Even though the applications of nuclear technology encompass diverse human endeavors, this study focuses only in industrial, medical and agriculture sectors. The applications of nuclear technology in both public agencies and private companies in those sectors are considered. This is the first time such a study is being undertaken in Malaysia, and as a starting point, the three year period spanning 2006-2008 are taken as the time frame for discerning trends of nuclear technology development in the country. This study was also in an indirect sense motivated by similar studies conducted in the USA

  19. Introduction

    DEFF Research Database (Denmark)

    Nielsen, Kirsten

    2009-01-01

    In this introduction, I present the main theme of the International Society of Religion, Literature and Culture's 14th conference that took place in Aarhus in October 2008. The theme of the conference was "Breaking the Norms. Reception, Transformation and Transgression in Religion, Literature...... of the story about Esau and Jacob. The rest of the introduction presents the six (revised) papers from the conference that are published in this special issue. The authors of these papers are Marie Vejrup Nielsen, James H. Thrall, Alyda Faber, Hans Jørgen Frederiksen, Stefanie Knauss og Hugh S. Pyper ....

  20. Introduction

    DEFF Research Database (Denmark)

    Bandak, Andreas; Janeja, Manpreet Kaur

    2018-01-01

    This introduction foregrounds waiting as a central analytical category to make way for ethnographic attention to uncertain interplays between doubting and hoping. Using a range of focused ethnographies which explore the centrality of waiting in social life, it offers a critical lens on understand......This introduction foregrounds waiting as a central analytical category to make way for ethnographic attention to uncertain interplays between doubting and hoping. Using a range of focused ethnographies which explore the centrality of waiting in social life, it offers a critical lens...... is negotiated in myriad ways, made more urgent in a neo-liberal era of simultaneous waiting and speeding up across scales....

  1. Introduction

    DEFF Research Database (Denmark)

    Peder Pedersen, Claus; Dehs, Jørgen

    2013-01-01

    Introduction to When Architects and Designers Write / Draw / Build / ? This anthology highlights the potentials and challenges for research in architecture and design. The included essays are based on papers given at a symposium held at the Aarhus School of Architecture in 2011 and contain a numb...

  2. Introduction

    NARCIS (Netherlands)

    Doreian, Patrick; Stokman, Frans N.

    2001-01-01

    Introduction to: The proceedings of a conference that was held on the analysis of repeated cross sections at the University of Nijmegen on June 15±16, 2000. This two-days meeting was attended by 75 participants from seven different countries (AUS, B, F, GER, NL, USA, UK) and from a wide array of

  3. Introduction

    DEFF Research Database (Denmark)

    Schmidt, Johannes Dragsbæk; Rasiah, Rajah

    2010-01-01

    This is a very interesting book. It is topical and is one of the few volumes that attempts to treat Southeast Asia as an integrated whole. The editors are methodologically ambitious, and they skillfully integrate a very large amount of diverse material in their introduction. I imagine that the bo...

  4. Introduction

    DEFF Research Database (Denmark)

    Pop, Paul; Alistar, Mirela; Stuart, Elena

    2015-01-01

    This chapter presents an introduction to the microfluidics field and microfluidic biochips. We discuss the main fluid propulsion principles used by modern microfluidic platforms, with a focus on “digital” microfluidic biochips, which are the topic of this book. Digital microfluidic biochips...

  5. Introduction

    DEFF Research Database (Denmark)

    Peder Pedersen, Claus; Dehs, Jørgen

    2013-01-01

    Introduction to When Architects and Designers Write / Draw / Build / ? This anthology highlights the potentials and challenges for research in architecture and design. The included essays are based on papers given at a symposium held at the Aarhus School of Architecture in 2011 and contain a number...

  6. Introduction

    DEFF Research Database (Denmark)

    Gjerdrum Pedersen, Esben Rahbek; Thusgaard Pedersen, Janni

    2013-01-01

    An introduction is presented in which the editors discuss various reports within the issue on topics including the shared value concept in the education and business, the role of corporate foundations in establishing cross-sector partnerships, and the mechanisms of governance in the cross...

  7. Introduction

    DEFF Research Database (Denmark)

    Petersen, Nils Holger; Sandbeck, Lars; Solten, Therese Bering

    2013-01-01

    Introduction to the Special Issue of Literature and Theology publishing articles based on selected papers from the international conference of the International Society for Religion, Literature and Culture (ISRLC) conference held at the Theological Faculty of the University of Copenhagen 19...

  8. Introduction

    DEFF Research Database (Denmark)

    Nielsen, Kirsten

    2009-01-01

    and transformation of the Bible in religious communities (Jewish and Christian). Each area is introduced by some general reflections. The following authors have contributed to the book: Kirsten Nielsen (Introduction and article), David Bugge (General reflections and article), Kirsten M. Andersen, Laura Feldt, Jakob...... Nissen, Marie Vejrup Nielsen (General reflections and article), Iben Damgaard, Maria Louise Odgaard Møller, Marianne Schleicher (General reflections and article), Johannes Nissen....

  9. Introduction

    Science.gov (United States)

    Klingshirn, C.

    The purpose of this introduction is - after a few general words on ZnO - to inform the reader about the history of ZnO research, the contents of this book and the intentions of the authors. Zinc oxide (ZnO) is a IIb-VI compound semiconductor. This group comprises the binary compounds of Zn, Cd and Hg with O, S, Se, Te and their ternary and quaternary alloys. The band gaps of these compounds cover the whole band gap range from E g ≈ 3. 94 eV for hexagonal ZnS down to semimetals (i.e., E g = 0 eV) for most of the mercury compounds. ZnO itself is also a wide gap semiconductor with E g ≈ 3. 436 eV at T = 0 K and (3. 37 ± 0. 01) eV at room temperature. For more details on the band structure, see Chaps. 4 and 6 or for a recent collection of data on ZnO, for example, [Rössler et al. (eds) Landolt-Börnstein, New Series, Group III, Vols. 17 B, 22, and 41B, 1999]. Like most of the compounds of groups IV, III-V, IIb-VI and Ib-VII, ZnO shows a tetrahedral coordination. In contrast to several other IIb-VI compounds, which occur both in the hexagonal wurtzite and the cubic zinc blende type structure such as ZnS, which gave the name to these two modifications, ZnO occurs almost exclusively in the wurtzite type structure. It has a relatively strong ionic binding (see Chap. 2). The exciton binding energy in ZnO is 60 meV [Thomas, J. Phys. Chem. Solids 15:86, 1960], the largest among the IIb-VI compounds, but by far not the largest for all semiconductors since, for example, CuCl and CuO have exciton binding energies around 190 and 150 meV, respectively. See, for example, [Rössler et al. (eds) Landolt-Börnstein, New Series, Group III, Vols. 17B, 22, and 41B, 1999; Thomas, J. Phys. Chem. Solids 15:86, 1960; Klingshirn and Haug, Phy. Rep. 70:315, 1981; Hönerlage et al., Phys. Rep. 124:161, 1985] and references therein. More details on excitons will be given in Chap. 6. ZnO has a density of about 5. 6 g / cm3 corresponding to 4. 2 × 1022 ZnO molecules per cm3 [Hallwig and

  10. Introduction

    DEFF Research Database (Denmark)

    Hesselager, Jens

    2017-01-01

    The fact that French grand opera as a genre was closely connected to the institution of the Paris Opéra, and, more generally, to the contemporary urban context of Paris, has meant that scholars have often focussed specifically on understanding the phenomenon in relation to the original Parisian...... context. This introduction, however, argues that French grand opera, precisely because of the status of Paris as a centre of European operatic culture, contributed to a process of cultural Europeanization, as seminal works of the genre achieved European fame, often very rapidly, and were performed...

  11. Introduction

    International Nuclear Information System (INIS)

    Davies, L.M.; Ianko, L.

    1998-01-01

    As a result of the popularity of the Agencies report 'Neutron Irradiation Embrittlement of Reactor Pressure Vessel Steels' of 1975, it was decided that another report on this broad subject would be of use. In the introduction the historic context is established, spanning a bow from the first sustained fission reactor in 1942 to contemporary developments. The subjects 'Irradiation Effects on Mechanical Properties', 'Neutron Fluence', 'Irradiation Effect Trends', 'Empirical Modelling of Irradiation Effects' and 'Mechanical Modelling' are addressed. There are also some remarks about the current state of the art, the migration of irradiation effects and about international programmes

  12. Introduction

    Directory of Open Access Journals (Sweden)

    Laurel Brake

    2013-04-01

    mso-fareast-language:JA;} When W. T. Stead died on the 'Titanic' he was the most famous Englishman on board. A mass of contradictions and a crucial figure in the history of the British press, Stead was a towering presence in the cultural life of late-Victorian and Edwardian society. In this introduction, we consider Stead as a ‘mass of contradictions’ and offer a few ways in which his prodigious output and activity might be understood.

  13. Introduction

    DEFF Research Database (Denmark)

    Petersen, Nils Holger; Sandbeck, Lars; Solten, Therese Bering

    2013-01-01

    Introduction to the Special Issue of Literature and Theology publishing articles based on selected papers from the international conference of the International Society for Religion, Literature and Culture (ISRLC) conference held at the Theological Faculty of the University of Copenhagen 19-21 Oc......-21 October 2012 with the theme: Cultures of Transition: Presence, Absence,Memory. The conference was organised by Nils Holger Petersen, Lars Sandbeck and Therese Bering Solten who were invited as guest editors for a volume of Literature and Theology based on the conference....

  14. Introduction

    DEFF Research Database (Denmark)

    Barwell, Richard; Clarkson, Philip; Halai, Anjum

    2016-01-01

    This chapter provides the introduction to this ICMI Study 21 volume. It includes: a discussion of the place of this study and its topic within ICME; a discussion of what is meant by the study title; and a brief historical account of research on this topic in mathematics education. The chapter also...... recounts the various stages of the study, including the development of the discussion document, the study conference, and the preparation of this volume. The latter parts of the chapter include syntheses of some key research ideas emerging from the volume, implications for policy and practice and issues...

  15. Introduction

    DEFF Research Database (Denmark)

    Barwell, Richard; Clarkson, Philip; Halai, Anjum

    2016-01-01

    This chapter provides the introduction to this ICMI Study 21 volume. It includes: a discussion of the place of this study and its topic within ICME; a discussion of what is meant by the study title; and a brief historical account of research on this topic in mathematics education. The chapter also...... recounts the various stages of the study, including the development of the discussion document, the study conference, and the preparation of this volume. The latter parts of the chapter include syntheses of some key research ideas emerging from the volume, implications for policy and practice and issues...... for further research....

  16. Introduction

    DEFF Research Database (Denmark)

    Høst, Jeppe Engset

    2015-01-01

    This chapter introduces the notion and theme of market-based fisheries management. The introduction of market mechanisms to distribute and manage fishing quota has internationally occurred since the 1980s but is increasingly on the political agenda. As privatization and transferability are promoted...... internationally, and by big players, it becomes even more crucial to understand its social and environmental implications. This chapter looks at the broader lines in the fisheries research and discusses the diverging views on market-based fisheries management. On one side market mechanisms are promoted...... for efficiency and fleet adaptation, and on the other, quota markets are accused of causing concentration and disturbing social relations....

  17. Introduction

    International Nuclear Information System (INIS)

    Zapata, F.; Garcia-Agudo, E.; Ritchie, J.C.; Appleby, P.G.

    2002-01-01

    Soil erosion and associated sedimentation are natural processes caused by water, wind and ice. Several of man's activities such as deforestation, overgrazing, changes in land use, and non-sustainable farming practices tend to accelerate soil erosion. Soil erosion and sedimentation cause not only on-site degradation of a non-renewable natural resource, but also off-site problems such as downstream sediment deposition in fields, floodplains and water streams. These problems and concern over the degradation of the landscape by erosion, and their impacts on soil fertility and crop productivity in agricultural land, water pollution, and sedimentation in lakes, reservoirs, and floodplains are well documented. Global estimates of economic damage from soil erosion and sedimentation have also been made. Recent focus on sustainability issues has resulted in increased attention on soil-degradation problems, in particular soil erosion and sedimentation. In view of increasing water scarcity and limited land resources to feed an ever-growing world population, there is an urgent need to obtain reliable quantitative data on the extent and rates of soil erosion worldwide to provide a more comprehensive assessment of the problem and to underpin the selection of effective soil-conservation technologies and sedimentation remediation strategies, including assessment of their economic and environmental impacts. This chapter describes the use of fallout 137 Cs as a tracer for measuring soil erosion and sedimentation, and the potential use of other radionuclides such as 210 Pb, and 7 Be for these studies. It provides an overview of the 137 Cs technique describing key assumptions and requirements, and advantages and limitations of the technique. Also, applications, recent developments, and future trends of the technique are covered. The chapter is completed with an introduction to the handbook and a list of selected references

  18. Introduction

    Directory of Open Access Journals (Sweden)

    Alfred Hornung

    2012-01-01

    Full Text Available Forty years after the assassination of Dr. Martin Luther King, Jr., the charismatic leader of the civil rights movement, Barack H. Obama was elected the first African American president of the United States of America in 2008. Although U.S. Attorney General Robert Kennedy had predicted in 1961 that a black person could be president like his brother “in the next thirty or forty years,” nobody really expected this kind of victory to come true.

  19. Introduction

    NARCIS (Netherlands)

    Vermeulen, P.A.M.; Hutte, E.; Vermeulen, P.; Hutte, E.

    2014-01-01

    For over 50 years Western initiatives to alleviate poverty were driven by a dominant logic that was based on the assumption that poor people were victims that needed to be helped by large-scale development aid projects to break the “vicious circle of poverty”. The late Peter Bauer said (1987: 30):

  20. Introduction

    NARCIS (Netherlands)

    Heuven, Vincent J. van; Quené, Hugo

    "Siebout Govaert Nooteboom (Sieb, [sip]) was born 65 years ago (19 April, 1939) in Makassar on the isle of Celebes (now Sulawesi), in the former Dutch East Indies, which is now part of the Republik Indonesia. Nooteboom obtained obtained a BA degree (kandidaats-examen, in 1963) in Dutch Language

  1. Introduction

    Directory of Open Access Journals (Sweden)

    Lorenzo Chiesa

    2009-05-01

    Full Text Available

    Introduction to the special issue of Cosmos and History, 'The Italian Difference: Between Nihilism and Biopolitics'.

     

    This volume brings together essays by different generations of Italian thinkers which address, whether in affirmative, problematizing or genealogical registers, the entanglement of philosophical speculation and political proposition within recent Italian thought. Nihilism and biopolitics, two concepts that have played a very prominent role within contemporary Italian thought, serve as the thematic foci around which the collection orbits, as it seeks to define the historical and geographical particularity of these notions as well their continuing impact on an international debate. The volume also covers the debate around ‘weak thought’ (pensiero debole, the feminist thinking of sexual difference, the re-emergence of political anthropology and the question of communism. The contributors provide contrasting narratives of the development of post

  2. Introduction

    OpenAIRE

    2014-01-01

    Every year, an estimated 25,000 to 50,000 species go extinct on the Earth owing to changes caused by human activity. Many international organisations including the World Conservation Union (IUCN) consider biological invasions to be the second most important cause of biodiversity loss worldwide, coming just after habitat destruction. On small islands, where biodiversity is both exceptionally original and exceptionally vulnerable, it is the main cause of species extinction. The New Caledonian a...

  3. Introduction

    OpenAIRE

    Staines, David

    2017-01-01

    “Personally,” Stephen Leacock declared in his preface to Sunshine Sketches of a Little Town (1912), “I would sooner have written Alice in Wonderland than the whole Encyclopedia Britannica.” Yet the worlds represented by Alice and the Encyclopedia, seemingly light years apart, are central to an understanding, appreciation, and assessment of the many worlds that commanded the attention of Stephen Butler Leacock (1869-1944). Humorist and humanist, economist and educator, professor and pundit, Le...

  4. 26 CFR 1.907(a)-0 - Introduction (for taxable years beginning after December 31, 1982).

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 9 2010-04-01 2010-04-01 false Introduction (for taxable years beginning after... States § 1.907(a)-0 Introduction (for taxable years beginning after December 31, 1982). (a) Effective... 1.907(c)-3. (f) Posted prices. Certain sales prices are disregarded when computing FOGEI for...

  5. Introduction

    International Nuclear Information System (INIS)

    Rusek, K.

    2010-01-01

    Heavy Ion Laboratory (HIL) is a part of the University of Warsaw, the largest university in Poland. It is the largest experimental nuclear physics laboratory in the country, equipped with a K=160 cyclotron. The first beam was extracted in 1993 and since that time HIL is an effective '' user facility '', serving up to the present time over 350 scientists from Poland and abroad and becoming a recognised element of the European Research Area. The research programme comprises nuclear and atomic physics, materials science, radiochemistry, biology and particle detector development. HIL is currently in a transition period and will shortly become an accelerator centre, operating two cyclotrons. Installation of a commercial proton-deuteron cyclotron (E p = 16.5 MeV) is under way in the HIL building. This accelerator will be used for the production of and research on radiopharmaceuticals for the Positron Emission Tomography (PET). Production of long-lived radiopharmaceuticals for other medical and life-science applications is also foreseen. HIL is located at the University Ochota Campus, together with Faculties of Biology, Geology, Chemistry and Mathematics. In the next few years the Faculty of Physics will also move from its present location at Hoza Street to the Ochota Campus and we are hoping for a much closer collaboration between HIL and the Faculty of Physics in the future. The Ochota Campus is located close to the main campus of the Medical University and its clinic. This opened a possibility for a very close collaboration, established a few years ago, between HIL and the Department of Nuclear Medicine of the Medical University. An especially important achievement at HIL in 2009 was the commissioning of the EAGLE spectrometer in May, followed by the experimental campaign. EAGLE is an array of gamma-ray detectors designed as a multi-configuration detector setup adjustable to the needs of several research groups. In the present configuration it is equipped with 12 anti

  6. Introduction

    Directory of Open Access Journals (Sweden)

    Renée Dickason

    2009-10-01

    Full Text Available It is fascinating to study history of propaganda in a British setting since it was a word which was used far less in Britain than in many other countries not least during the years leading up to the Second World War. […] Whether or not contemporaries in any generation used the word—and it is a word which itself demands detailed chronological charting— historians are compelled to use it. Sometimes its role is obvious, even crude, whether words or pictures are being employed. At other times its...

  7. Introduction

    International Nuclear Information System (INIS)

    Jastrzebski, J.

    2004-01-01

    Full text: The year 2003 was a consecutive period of a regular activity of the Heavy Ion Laboratory. The Cyclotron was delivering the heavy ion beams ranging from 11 B to 40 Ar to ten different experiments during more than 2000 hours. A few teams were able to finalize their previous years data collection by papers published in high-ranked journals. Other teams published in the proceedings of the international conferences their invited talks or oral contributions. Thirteen publication in ISI listed journals appeared last year basing on the data obtained using Warsaw machine. A similar number was published by the Laboratory staff using external facilities. The modest technical upgrades presented in this Report were achieved almost with no cost above the salaries. The 15 % decrease of the previous years running subvention from the Ministry of Science and Informatics accompanied by a consecutive refusal to fund the new ECR ion source makes the status of the Laboratory as the nuclear physics center in a very precarious position. The situation looks much more promising with the new project: the creation of an interdisciplinary Laboratory - the Warsaw Positron Emission Tomography Centre, launched by the Heavy Ion Laboratory and the Nuclear Medicine Department at the Clinical Hospital of the Warsaw Academy of Medicine in 2001. In 2003 the Warsaw Consortium for PET Collaboration (WCPC) was created and presently it takes an active role in the project preparation. The WCPC will dispose of a single radiopharmaceuticals production unit located at HIL and equipped with a commercial proton/deuteron cyclotron, chemical units and quality control laboratory. The PET CT, PET or adapted SPECT scanners will be successively located in the Warsaw hospital centers, starting with the medical unit closest (500 m) to the radiopharmaceutical production place. The participation in the WCPC of numerous University and Academy of Sciences units will promote the Warsaw Centre activity in research

  8. Introduction

    OpenAIRE

    2013-01-01

    The present expert group review survey is timely: existing dengue fever control methods have not succeeded in halting the spread of the disease in either its classic form or its haemorrhagic form, in any of the three French départements of America (the FDAs: Guadeloupe, French Guiana and Martinique). The world picture is no more reassuring: dengue has been on the increase throughout the tropics and subtropics over the past forty years. An estimated two and a half billion people are at risk; t...

  9. Introduction

    Science.gov (United States)

    Eiler, John M.

    Geological models of subduction zones impact thinking about many of the central problems in the structure, dynamics, chemistry, and history of the solid earth. Should those models change, the effects will reach across the earth sciences. We are currently in the midst of such a change, brought on by several causes. First, the earth science community recently began an organized, multi-disciplinary study of subduction zones by way of the National Science Foundation's "Margins initiative." This has improved the quality of our descriptions of key focus areas and should continue to do so for the next several years. Less purposefully but of equal importance, several of the debates in subduction zone research have evolved in recent years, making us revisit both recent and old observations in a new light. This book consists of descriptions of these advances, written by the some of the leading participants. I describe the origin and organization of the book in the preface; here I review the context of previous thought regarding convergent margins, with particular focus on the link between tectonics and magmatism, and point out questions raised in the following chapters.

  10. Introduction

    Science.gov (United States)

    Cheng, K. S.; Romero, Gustavo E.

    In the last 15 years, gamma-ray astronomy has evolved from a promis-ing but rather exotic branch of astronomical science to become a mature field of research with its own well-defined referents: cosmic gamma-ray sources. These sources include some of the most extraordinary objects known to human beings: pulsars, active galactic nuclei, accreting black holes, supernova remnants, and gamma-ray bursts. A significant com-ponent of our current knowledge of such objects is the direct result of astronomical measurements of the high-energy photons they produce. Satellite-borne instruments that can detect gamma-rays in the Earth's orbit or in deep space and atmospheric air shower detectors that re-construct the energy and direction of high-energy photons through the Cherenkov light generated in particle showers produced in the Earth's atmosphere have been the basic exploratory tools of gamma-ray astron-omy. For many years, however, cosmic gamma-ray sources defied all attempts at their detection.

  11. Introduction

    International Nuclear Information System (INIS)

    Rusek, K.

    2011-01-01

    This year was a year of hope for change. We attempted to become one of the laboratories of the '' Road Map of National Research Infrastructure '' of the Ministry of Science and Higher Education (MNiSW) of Poland. At the beginning of the year we were informed by the MNiSW that we had passed the first selection with the suggestion that we prepare, as the next step, a joint project with the H. Niewodniczanski Institute of Nuclear Physics of the Polish Academy of Science (IFJ) in Cracow. On the 21 st of April the Rector of the University of Warsaw and the director of IFJ created the consortium '' National Cyclotron Laboratory '', signing an agreement between our two institutions. In this way the two largest nuclear physics institutes in Poland, with two operating cyclotrons (a proton cyclotron in Cracow and the heavy-ion cyclotron in Warsaw) and two others becoming operational within the next two years, united their efforts and prepared a common project devoted to fundamental research in nuclear physics and its medical applications. Unfortunately, our project was not selected for the '' Road Map '' - a decision of the MNiSW incomprehensible to us. Since such a document must be regularly updated we will continue our efforts to find a place on the national '' Road Map ''. Despite our lack of success in our own country, on the European level our laboratory was recognised by the Nuclear Physics European Collaboration Committee (NuPECC). This important international body released in December the '' NuPECC Long Range Plan 2010, Perspectives of Nuclear Physics in Europe ''. Our laboratory is listed among other European small scale facilities with the recommendation - '' These national and other university based facilities are needed for specific experimental programmes, development and testing of new instruments and to provide education of next-generation researchers from university groups ''. It was not an easy year for experimentalists. In the spring the new Supernanogan

  12. Introduction

    Directory of Open Access Journals (Sweden)

    Laura Guidi

    2016-03-01

    Full Text Available Ten years ago, a group of women, professors, senior and junior researchers, started La camera blu, the first gender studies review of the University of Naples Federico II. The War and the women’s involvement was decided to be the first topic to deal with. The choice was due to two main considerations: a the difference that crucial historical moments, wars and revolutions particularly, meant for men and women; b the conspicuous absence of women’s experience in literature and history accounts. The idea that war is “ men’s business, not ladies” was at the heart of it. In not a surprisingly way, new aspects were pointed out such as the split between national and private history, the complex way the cultural memory of a nation is developed, the separation between individual ideology and national ideology.

  13. Introduction

    Directory of Open Access Journals (Sweden)

    Helge Hvid

    2015-06-01

    Full Text Available In this issue we present six articles, which are quite different in both scope and methodology. Changes in the quality of working life are however a common interest in all articles. Two articles deal with the tension between passion and exploitation in current working life—one is a theoretical article, the other is primarily empirical. Two articles deal with the effects of flexibility on the quality of working life: one examined the effects of the ‘flexicurity model’ on the quality of working life; the other examined how the flexibility of work in elder care affects the quality of working life.  Another article examines the importance of personal relationship to the nearest leader for well-being. In the last article the position of women at the labor market is analyzed in the perspective of the last 50 years (...

  14. Introduction

    International Nuclear Information System (INIS)

    Edwards, D.A.

    1989-01-01

    The Tevatron project included the construction of three new synchrotrons, but common usage has attached that name to the superconducting ring. In the mid 70's the growing appreciation of the potential of hadron colliders added an additional function to the requirements for the superconducting ring. It should act as a storage ring as well. The main special design features of the superconducting accelerator are the magnets themselves and the cryogenics to cool them. But other systems are also required such as magnet power systems and vacuum systems. The Tevatron was commissioned in 1983. Over four years after its commissioning, the Tevatron is still very much a prototype accelerator, as much a research instrument in its own right as it is a high energy physics tool

  15. Introduction

    Directory of Open Access Journals (Sweden)

    Feltes Thomas

    2013-07-01

    Full Text Available The aim of the three-year European-wide research project “Gender-based Violence, Stalking and Fear of Crime” (2009-2011 was to verify this hypothesis and to collect, analyse and compare relevant data in five European countries. The EU project, which has been funded through the program “Prevention of and Fight against Crime” and initiated by the EU Commission on General Justice, Freedom and Security, was coordinated by the Department of Criminology at the Ruhr University Bochum in Germany. In addition, the consortium covers the University of Bologna, Jagiellonian University in Cracow/Poland, Universitát Autonoma de Barcelona/Spain and Keele University in the U.K.The victimisation of young women through sexual harassment, stalking and sexual violence, along with their fear of crime, and their need for support, were the subject of an online questionnaire made available at universities in Germany, Italy, Spain, Poland and Britain.

  16. Introduction

    Science.gov (United States)

    Cohen, E. G. D.

    deduced for irreversible processes (C. Jarzynski). The survey of non-equilibrium steady states in statistical mechanics of classical and quantum systems employs heat bath models and the random matrix theory input. The quantum heat bath analysis and derivation of fluctuation-dissipation theorems is performed by means of the influence functional technique adopted to solve quantum master equations (D. Kusnezov). Chapter II deals with an issue of relaxation and its dynamical theory in both classical and quantum contexts. Pollicott-Ruelle resonance background for the exponential decay scenario is discussed for irreversible processes of diffusion in the Lorentz gas and multibaker models (P. Gaspard). The Pollicott-Ruelle theory reappears as a major inspiration in the survey of the behaviour of ensembles of chaotic systems, with a focus on model systems for which no rigorous results concerning the exponential decay of correlations in time is available (S. Fishman). The observation, that non-equilibrium transport processes in simple classical chaotic systems can be described in terms of fractal structures developing in the system phase space, links their formation and properties with the entropy production in the course of diffusion processes displaying a low dimensional deterministic (chaotic) origin (J. R. Dorfman). Chapter III offers an introduction to the theory of dynamical semigroups. Asymptotic properties of Markov operators and Markov semigroups acting in the set of probability densities (statistical ensemble notion is implicit) are analyzed. Ergodicity, mixing, strong (complete) mixing and sweeping are discussed in the familiar setting of "noise, chaos and fractals" (R. Rudnicki). The next step comprises a passage to quantum dynamical semigroups and completely positive dynamical maps, with an ultimate goal to introduce a consistent framework for the analysis of irreversible phenomena in open quantum systems, where dissipation and decoherence are crucial concepts (R

  17. Introduction

    Science.gov (United States)

    de Graauw, T.

    2010-09-01

    As this editorial is written, we have seven antennas at the Chajnantor plateau, the "High Site". Seven antennas means twenty-one baselines, i.e. more than twice as many as we had only two months ago. As you know, the bonus we have in interferometry is that the the number of baselines increases roughly with the square of the available antennas. The image quality can be further enhanced, because the projection of a celestial source onto the existing baselines changes due to the rotation of the Earth. A large number of baselines is important but not sufficient to fulfill one important promise of ALMA, namely to provide crisp images. Unlike the sharp images from the Hubble Space Telescope, images from ground based optical or radio telescopes are blurred by the Earth's atmosphere. It is the Holy Grail of observing astronomy to overcome such atmospheric effects. Recently, ALMA has made a big step toward this goal by using Water Vapor Radiometers operating at 183 GHz to measure the amount of atmospheric water vapor at any instant in the line of sight of each antenna, and applying a corresponding correction to the astronomical data received. This not only improves the image quality, it is essential for using ALMA at its lowest wavelengths of around 0.3mm and at baselines exceeding several kilometers. Achieving this has a been a collaborative effort involving many parts of the project and there are all to be congratulated. JAO has now moved into our new Santiago Central Office in Vitacura next to the ESO premises, ending a phase of two years were Santiago based staff was distributed in two different buildings. This new ALMA office will also host the ALMA archive. Although ALMA users are normally not expected to come to Chile to observe, there will be office space for visitors, since ALMA has been and will always be a cooperation of people from many countries and many fields of science and engineering. This newsletter contains a list of workshops, schools and conferences

  18. Introduction

    Science.gov (United States)

    Narlikar, J. V.; Sathyaprakash, B. S.

    2014-03-01

    The ICGC Meetings: 1987-2011 When India became an independent nation in 1947, the presence of Jawaharlal Nehru on the scene, as the Prime Minister was a fortunate circumstance. For, Nehru was a visionary, who believed that the future of the new nation should be guided by science and technology (S & T), and so with like-minded scientists like, Shanti Swarup Bhatnagar, Homi Bhabha, Meghnad Saha, and Daulatsingh Kothari in leading positions, Nehru set about creating an extensive infrastructure for S & T. The initiatives taken in and around 1947 began to yield dividends in a couple of decades, and by the late 60s and early 70s, major S & T organizations and associated trained human resources were making significant contributions to the country's development, both material and intellectual. Amongst these may be included, the creation of various scientific societies devoted to specific subjects. These came in response to the urge of scientists to meet as a group for discussions in their fields of research. So, it was in 1969, a number of research workers in the field of general relativity and gravitation (GRG), who had gathered for a workshop in Ahmedabad, resolved to form a society for GRG. The initiative was taken by P C Vaidya, who pointed out the advantages of forming such a recognized group, mentioning that the international community of workers in GRG had already formed such a society. The Indian Association for General Relativity and Gravitation (IAGRG), thus, came up in 1969 with the veteran relativist V V Narlikar, as its first President. Some three years later, the astronomical community responding to a similar urge, formed the Astronomical Society of India (ASI), under the presidency of Vainu Bappu, the Founder Director of the Indian Institute of Astrophysics, Bangalore. Since the days of discovery of quasars in 1963, there has been an alliance between gravitation theorists and astrophysicists, resulting in the Texas Symposia, which are held once every two

  19. Introduction

    International Nuclear Information System (INIS)

    Jastrzebski, J.

    2006-01-01

    with our mechanical workshop, this detector is now awaiting to receive the first heavy ion beam and to pass the operation tests. Besides the heavy ion machine, the Laboratory will soon be equipped with the second, low energy (16.5 MeV, p), high current proton - deuteron cyclotron for the production of short lived radiopharmaceuticals for the Positron Emission Tomography. As already presented in the last year Annual Report, this will allow the creation of an interdisciplinary laboratory, the Warsaw Positron Emission Tomography Centre. This project was launched by the Heavy Ion Laboratory and the Nuclear Medicine Department at the Clinical Hospital of the Medical University in Warsaw in 2001. In 2003 the Warsaw Consortium for PET Collaboration (WCPC) was created and presently it plays an active role in the project preparation. The WCPC will possess a single radiopharmaceuticals production unit located at HIL and will be equipped with a commercial proton/deuteron cyclotron, chemical units and a quality control laboratory. The PET CT, PET or adapted SPECT scanners will be successively located in the Warsaw hospital centers, starting with the medical unit closest (500 m) to the radiopharmaceuticals production place. The participation in the WCPC of numerous University and Polish Academy of Sciences units will promote the Warsaw PET Centre activity in research and educational area. The planned purchase of the micro - PET animal scanner will substantially help in this activity. After four years of efforts, in 2004 the Warsaw PET project obtained the financial support from the Ministry of Sciences and Informatization, which allocated 10 MPLN (about 2.4 MEUR) for the equipment of the Radiopharmaceuticals Production Department of the Warsaw PET Centre. At the end of the same year the Board of Governors of the International Atomic Energy Agency accepted our project of Technical Cooperation with the Agency and allocated almost 0.9 MUS$ for this project. The same year, Ministry of

  20. Introduction

    Science.gov (United States)

    Warwick, Peter D.; Hook, Robert W.; SanFilipo, John R.; Warwick, Peter D.; Karlsen, Alexander K.; Merrill, Matthew D.; Valentine, Brett J.

    2011-01-01

    The National Coal Resource Assessment (NCRA) team of the U.S. Geological Survey (USGS) has assessed the quantity and quality of coal beds and zones that could be mined during the next 20 years or more. Geologic, geochemical, and resource information was collected and compiled for the five major coal-producing regions of the United States: the Appalachian Basin, Illinois Basin, Northern Rocky Mountains and Great Plains, Colorado Plateau, and the Gulf of Mexico Coastal Plain, (Gulf Coast) (Figure 1). In particular, the NCRA assessed coal-quality information and characterized environmentally significant trace elements, such as arsenic and mercury, that are defined in and administered by 1990 Clean Air Act Amendments (U.S. Environmental Protection Agency, 1990). The results of various USGS coal assessment efforts may be found at: http://energy.cr.usgs.gov/coal/coal_assessments/index.html, and a summary of the results from all assessment areas can be found in Ruppert et al. (2002) and Dennen (2009).

  1. Introduction

    Science.gov (United States)

    Öchsner, Andreas; Augustin, Christian

    Nature frequently uses cellular and porous materials for creating load-carrying and weight-optimized structures. Thanks to their cellular design, natural materials such as wood, cork, bones, and honeycombs fulfill structural as well as functional demands. For a long time, the development of artificial cellular materials has been aimed at utilizing the outstanding properties of biological materials in technical applications. As an example, the geometry of honeycombs was identically converted into aluminum structures which have been used since the 1960s as cores of lightweight sandwich elements in the aviation and space industries. Nowadays, in particular, foams made of polymeric materials are widely used in all fields of technology. For example, Styrofoam® and hard polyurethane foams are widely used as packaging materials. Other typical application areas are the fields of heat and sound absorption. During the last few years, techniques for foaming metals and metal alloys and for manufacturing novel metallic cellular structures have been developed. Owing to their specific properties, these cellular materials have considerable potential for applications in the future. The combination of specific mechanical and physical properties distinguishes them from traditional dense metals, and applications with multifunctional requirements are of special interest in the context of such cellular metals. Their high stiffness, in conjunction with a very low specific weight, and their high gas permeability combined with a high thermal conductivity can be mentioned as examples. Cellular materials comprise a wide range of different arrangements and forms of cell structures. Metallic foams are being investigated intensively, and they can be produced with an open- or closed-cell structure, cf. Fig. 1.1. Their main characteristic is their very low density. The most common foams are made of aluminum alloys. Essential limiting factors for the utilization are unevenly distributed material

  2. Introduction

    Directory of Open Access Journals (Sweden)

    Anne-Laure Van Bruaene

    2016-03-01

    Full Text Available After 450 years the Beeldenstorm of 1566 still deserves our careful historical analysis because it was unquestionably a game changer in Netherlandish politics and culture. More generally, we believe that iconoclasm breaks open cultural codes and thereby helps us to understand past societies. While we must thank the previous generations of historians for taking the iconoclasts seriously, the historians and art historians in this issue go a step further by also taking seriously the targets of iconoclasts – lay Catholic devotion and religious material culture. This theme number analyses the dialectics between iconoclasts and the material objectsthey targeted, between those who attacked and those who actively or passively defended the traditional community, between those who destroyed and those who restored or reinvented the religious patrimony, and in doing so reveals what was at stake in the sixteenth-century Low Countries.  Na 450 jaar verdient de Beeldenstorm van 1566 nog steeds een grondige historische analyse, aangezien er weinig twijfel kan bestaan over de enorme impact op de politiek en cultuur van de Nederlanden. Meer algemeen beschouwen wij iconoclasme als een kraker van culturele codes die ons helpt samenlevingen uit het verleden te begrijpen. Vorige generaties historici hebben zich vooral verdiept in de motieven van de iconoclasten, deze groep historici en kunsthistorici gaat verderdoor ook de doelwitten van de iconoclasten – de katholieke lekendevotie en de religieuze materiële cultuur – tot object van studie te maken. Dit themanummer ontrafelt de dialectiek tussen iconoclasten en de materiële cultuur die ze viseerden, tussen mannen en vrouwen die de traditionele gemeenschap aanvielen en deze die haar actief of passief verdedigden, tussen zij die het religieuze patrimonium vernielden en zij die het herstelden of herijkten. Op die manier wordt duidelijk waar het om draaide in de zestiende-eeuwse Nederlanden.

  3. Introduction

    Science.gov (United States)

    2016-11-01

    A year has passed since Raymond left us, but for many of us it seems like it was yesterday. Indeed, since his departure last July, not a week or even a day has gone by without his former collaborators, students, colleagues having a thought for him. Some initiatives have already been taken in order to celebrate Raymond's memory. The special day for Raymond organized at CERN last December was an opportunity to celebrate this exceptional man. In Annecy, with the implication of CERN and Marseille and thanks to a spontaneous and generous gift of Raymond's wife Marie-Françoise and their children Olivier and Thierry, the opening of a special room containing a huge collection of scientific books of Raymond is almost completed. It is in the same spirit that the present editors decided to dedicate a special issue of Nuclear Physics in memory of Raymond. In the following pages, some important problems Raymond was interested in are presented, discussed and sometimes solved. The diversity of topics in this issue reflects well the extent of Raymond's interests in Physics and Mathematics. Raymond was not only a gifted man for the so-called theoretical sciences, mathematics and physics, but he was also passionate about arts, music, drawing and of course literature, just as he was a leader always ready to bring his help and share his deep knowledge in physics and mathematics with others. Many people were deeply touched by Paul Sorba's tribute during Raymond's funeral. This is why we asked Paul to translate his speech, originally given in French, which seemed to us a perfect Prolegomena for this special volume of Nuclear Physics. The volume "Mathematical Foundations of Quantum Field Theory" is organized as follows: General and historical contributions

  4. Long-Term Monitoring of Field Trial Sites with Genetically Modified Oilseed Rape (Brassica napus L.) in Saxony-Anhalt, Germany. Fifteen Years Persistence to Date but No Spatial Dispersion

    Science.gov (United States)

    Belter, Anke

    2016-01-01

    Oilseed rape is known to persist in arable fields because of its ability to develop secondary seed dormancy in certain agronomic and environmental conditions. If conditions change, rapeseeds are able to germinate up to 10 years later to build volunteers in ensuing crops. Extrapolations of experimental data acted on the assumption of persistence periods for more than 20 years after last harvest of rapeseed. Genetically-modified oilseed rape—cultivated widely in Northern America since 1996—is assumed not to differ from its conventional form in this property. Here, experimental data are reported from official monitoring activities that verify these assumptions. At two former field trial sites in Saxony-Anhalt genetically-modified herbicide-resistant oilseed rape volunteers are found up to fifteen years after harvest. Nevertheless, spatial dispersion or establishment of GM plants outside of the field sites was not observed within this period. PMID:26784233

  5. Long-Term Monitoring of Field Trial Sites with Genetically Modified Oilseed Rape (Brassica napus L.) in Saxony-Anhalt, Germany. Fifteen Years Persistence to Date but No Spatial Dispersion.

    Science.gov (United States)

    Belter, Anke

    2016-01-16

    Oilseed rape is known to persist in arable fields because of its ability to develop secondary seed dormancy in certain agronomic and environmental conditions. If conditions change, rapeseeds are able to germinate up to 10 years later to build volunteers in ensuing crops. Extrapolations of experimental data acted on the assumption of persistence periods for more than 20 years after last harvest of rapeseed. Genetically-modified oilseed rape-cultivated widely in Northern America since 1996-is assumed not to differ from its conventional form in this property. Here, experimental data are reported from official monitoring activities that verify these assumptions. At two former field trial sites in Saxony-Anhalt genetically-modified herbicide-resistant oilseed rape volunteers are found up to fifteen years after harvest. Nevertheless, spatial dispersion or establishment of GM plants outside of the field sites was not observed within this period.

  6. Fifteen-year trend in information on the World Wide Web for patients with rheumatoid arthritis: evolving, but opportunities for improvement remain.

    Science.gov (United States)

    Castillo-Ortiz, Jose Dionisio; de Jesus Valdivia-Nuno, Jose; Ramirez-Gomez, Andrea; Garagarza-Mariscal, Heber; Gallegos-Rios, Carlos; Flores-Hernandez, Gabriel; Hernandez-Sanchez, Luis; Brambila-Barba, Victor; Castaneda-Sanchez, Jose Juan; Barajas-Ochoa, Zalathiel; Suarez-Rico, Angel; Sanchez-Gonzalez, Jorge Manuel; Ramos-Remus, Cesar

    2016-09-01

    The aim of this study was to assess the changes in the characteristics of rheumatoid arthritis information on the Internet over a 15-year period and the positioning of Web sites posted by universities, hospitals, and medical associations. We replicated the methods of a 2001 study assessing rheumatoid arthritis information on the Internet using WebCrawler. All Web sites and pages were critically assessed for relevance, scope, authorship, type of publication, and financial objectives. Differences between studies were considered significant if 95 % confidence intervals did not overlap. Additionally, we added a Google search with assessments of the quality of content of web pages and of the Web sites posted by medical institutions. There were significant differences between the present study's WebCrawler search and the 2001-referent study. There were increases in information sites (82 vs 36 %) and rheumatoid arthritis-specific discussion pages (59 vs 8 %), and decreases in advertisements (2 vs 48 %) and alternative therapies (27 vs 45 %). The quality of content of web pages is still dispersed; just 37 % were rated as good. Among the first 300 hits, 30 (10 %) were posted by medical institutions, 17 of them in the USA. Regarding readability, 7 % of these 30 web pages required 6 years, 27 % required 7-9 years, 27 % required 10-12 years, and 40 % required 12 or more years of schooling. The Internet has evolved in the last 15 years. Medical institutions are also better positioned. However, there are still areas for improvement, such as the quality of the content, leadership of medical institutions, and readability of information.

  7. Survival With Dialysis Versus Kidney Transplantation in Adult Hemolytic Uremic Syndrome Patients: A Fifteen-Year Study of the Waiting List.

    Science.gov (United States)

    Santos, Alfonso H; Casey, Michael J; Wen, Xuerong; Zendejas, Ivan; Rehman, Shehzad; Womer, Karl L; Andreoni, Kenneth A

    2015-12-01

    Survival data are lacking for kidney transplant recipients with rare native end-stage renal disease (ESRD) etiologies. There is currently no large registry study comparing dialysis versus kidney transplantation survival outcomes of waitlisted adults with hemolytic uremic syndrome (HUS). We retrospectively studied adult-HUS end-stage renal disease patients (n = 559) placed on the US kidney transplant waitlist in 1996 to 2011. We analyzed 5-year transplantation and patient survival probabilities and risk factors using Kaplan-Meier and Cox hazards models, respectively. Using similar models, waitlist and transplantation outcomes of patients with diabetes mellitus (DM), hypertension (HTN), and glomerulonephritis (GN) were analyzed, and then compared with HUS patients. Compared with waitlisted adult HUS patients on dialysis, 5-year mortality risks were 73% and 48% lower in recipients of living (hazard ratio [HR], 0.27, 95% confidence interval [95% CI], 0.11-0.65) and standard deceased (HR, 0.52; 95% CI, 0.29-0.94) donor kidney transplants, respectively. Mortality risks over 5 years were 44%, 50%, 54%, and 55% lower in the overall transplant recipient cohorts than in the dialysis-maintained cohorts within the HUS (HR, 0.56; 95% CI, 0.35-0.91), HTN (HR, 0.50; 95% CI, 0.48-0.52), GN (HR, 0.46; 95% CI, 0.44-0.49), and DM (HR, 0.45; 95% CI, 0.44-0.47) groups, respectively. Five-year transplantation probability in the waitlisted HUS cohort was 60% versus 42% to 49% (P dialysis in waitlisted adults with HUS. On the waitlist, the 5-year transplantation probability was higher in HUS than in DM and HTN patients.

  8. The International Science and Technology Center (ISTC) - Fifteen-Year Experience in Management of Innovative Nuclear and Other Programs (Information Review)

    Energy Technology Data Exchange (ETDEWEB)

    Gudowski, W.; Tocheny, L.V. [ISTC - International Science and Technology Center, Krasnoproletarskaya 32-34, PO Box 20, 127473 Moscow (Russian Federation)

    2009-06-15

    Introduction: The ISTC is a unique international organization created in Moscow in 1994 by Russia, USA, EU and Japan. Later Korea and Canada, and several CIS countries as well acceded to ISTC. The basic idea behind establishing the ISTC was to support non-proliferation of the mass destruction weapons technologies by redirecting former Soviet weapons scientists to peaceful research thus preventing the drain of dangerous knowledge and expertise from Russia and other CIS countries. Presently, the ISTC now has 40 member countries (27 from EU), representing the CIS, Europe, Asia, and North America. The Partner list includes over 200 organizations and leading industrial companies from all ISTC parties. Numerous science and technology projects were realized with the ISTC support in different areas, from bio-technologies and environmental problems to all aspects of nuclear studies, including those focused on the development of effective innovative concepts and technologies in the nuclear field, in general, and for improvement of nuclear safety, in particular. Concept: Challenge of the World Nuclear Community is to prove to Public over the World, that newly proposed nuclear concepts are safe and effective. The only acceptable method, which is trusted and accepted by Public both now and always, is basic-type and demonstration-type Experiment, in advance of computer or paper-type arguing. Important that results of these experiments are to be available for international analysis and validation. Problems are that nuclear experiments are very complex, its require special licensing, long time preparation, appealing to high-skilled personnel, purchasing by nuclear and special materials and tools, as a result - raised budgeting. In this sense the ISTC clients (first of all - nuclear and 'nuclear weapon' institutes in Russia and CIS) have all set, ready, licensed, and equipped unique nuclear installations, high-skilled personnel, good cooperation. Essential, that the ISTC

  9. Prevalence and contributing factors to attention deficit hyperactivity disorder: a study of five- to fifteen-year-old children in Zhabei District, Shanghai.

    Science.gov (United States)

    Jin, Wenlan; Du, Yasong; Zhong, Xiangyang; David, Coghill

    2014-12-01

    This work aims to understand the features among 5- to 15-year-old children with attention deficit hyperactivity disorder (ADHD) in Zhabei District in Shanghai. Children with ADHD were studied using general background questionnaire, ADHD symptom rating questionnaire, and cluster-stratified sampling. A total of 9,900 valid questionnaires were utilized in this study. We conducted diagnostic interviews with suspected ADHD children and their parents using the criteria of the Diagnostic and Statistical Manual of Mental Disorders (4th Edition) for ADHD. The prevalence rate of ADHD among the children was 4.6%, of which 2.4%, 0.4%, and 1.8% had ADHD-I ADHD-HI, and ADHD-C types, respectively. The prevalence rates in boys and girls were 6.6% and 2.7% (ratio, 2.41 : 1), respectively. Significant differences in prevalence rate were found among children with different age groups and ADHD types. Children aged 7-10 years had the highest prevalence rate (6.3%). Externally, residence children had higher prevalence than local residents. Significant differences in prevalence rate were also found among children with parents having different educational and socioeconomic level. The prevalence of ADHD-HI was higher than the other two types. The highest prevalence was observed in 7- to 10-year-old children. The influential factors of ADHD prevalence were age, gender, and educational level. © 2013 The Authors. Asia-Pacific Psychiatry published by Wiley Publishing Asia Pty Ltd.

  10. Building Technologies Program Multi-Year Program Plan Technology Validation and Market Introduction 2008

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2008-01-01

    Building Technologies Program Multi-Year Program Plan 2008 for technology validation and market introduction, including ENERGY STAR, building energy codes, technology transfer application centers, commercial lighting initiative, EnergySmart Schools, EnergySmar

  11. Neck pain in a sample of Greek urban population (fifteen to sixty-five years): analysis according to personal and socioeconomic characteristics.

    Science.gov (United States)

    Stranjalis, George; Kalamatianos, Theodosis; Stavrinou, Lampis C; Tsamandouraki, Kiki; Alamanos, Yiannis

    2011-07-15

    A cross-sectional study of neck pain and its related aspects in a sample of Greek urban population (15-65 years). To estimate the prevalence of neck pain in a Greek urban population (15-65 years) and to study the association of neck pain with several socioeconomic and demographic characteristics. The results of several prevalence studies carried out in different populations indicate a high frequency of neck pain in the general population. Socioeconomic and demographic factors are likely to influence neck pain frequency and neck pain-associated burden. A 1000-person sample of the general Greek population (15-65 years) living in the Greek capital and other urban centers of the country was selected by multiple-stage sampling, with definition of sample quotas based on demographic characteristics. Data on neck pain and its related aspects, including healthcare utilization, as well as demographic, socioeconomic, and employment data, were collected through personal interviews. Of the 204 individuals who reported neck pain during the last month, 35 (17.2%) consulted a physician, 72 (35.3%) received medication, and 15 (7.4%) stayed in bed for some time, during this period and because of neck pain. The mean duration of pain for individuals who reported neck pain during the last month was 12 days. A total of 8.6% of working individuals who experienced neck pain during the last month reported work absenteeism due to this pain, during this period; the mean duration of absence was 4.6 days. Neck pain frequency was related to several sociodemographic factors. Female sex, increased age, and being married showed a statistically significant association with the presence of neck pain. The present results indicate that neck pain is a common symptom in the studied Greek urban population. Nevertheless, relatively few individuals seek medical advice for this symptom. Neck pain frequency is associated with age, sex, and marital status.

  12. A year of mentoring in academic medicine: case report and qualitative analysis of fifteen hours of meetings between a junior and senior faculty member.

    Science.gov (United States)

    Rabatin, Joseph S; Lipkin, Mack; Rubin, Alan S; Schachter, Allison; Nathan, Michael; Kalet, Adina

    2004-05-01

    We describe a specific mentoring approach in an academic general internal medicine setting by audiotaping and transcribing all mentoring sessions in the year. In advance, the mentor recorded his model. During the year, the mentee kept a process journal. Qualitative analysis revealed development of an intimate relationship based on empathy, trust, and honesty. The mentor's model was explicitly intended to develop independence, initiative, improved thinking, skills, and self-reflection. The mentor's methods included extensive and varied use of questioning, active listening, standard setting, and frequent feedback. During the mentoring, the mentee evolved as a teacher, enhanced the creativity in his teaching, and matured as a person. Specific accomplishments included a national workshop on professional writing, an innovative approach to inpatient attending, a new teaching skills curriculum for a residency program, and this study. A mentoring model stressing safety, intimacy, honesty, setting of high standards, praxis, and detailed planning and feedback was associated with mentee excitement, personal and professional growth and development, concrete accomplishments, and a commitment to teaching.

  13. Peer-led training and assessment in basic life support for healthcare students: synthesis of literature review and fifteen years practical experience.

    Science.gov (United States)

    Harvey, P R; Higenbottam, C V; Owen, A; Hulme, J; Bion, J F

    2012-07-01

    In 1995, the University of Birmingham, UK, School of Medicine and Dentistry replaced lecture-based basic life support (BLS) teaching with a peer-led, practical programme. We present our 15-yr experience of peer-led healthcare undergraduate training and examination with a literature review. A literature review of healthcare undergraduate peer-led practical skills teaching was performed though Pubmed. The development of the Birmingham course is described, from its inception in 1995-2011. Training methods include peer-led training and assessment by senior students who complete an European Resuscitation Council-endorsed instructor course. Student assessors additionally undergo training in assessment and communication skills. The course has been developed by parallel research evaluation and peer-reviewed publication. Course administration is by an experienced student committee with senior clinician support. Anonymous feedback from the most recent courses and the current annual pass rates are reported. The literature review identified 369 publications of which 28 met our criteria for inclusion. Largely descriptive, these are highly positive about peer involvement in practical skills teaching using similar, albeit smaller, courses to that described below. Currently approximately 600 first year healthcare undergraduates complete the Birmingham course; participant numbers increase annually. Successful completion is mandatory for students to proceed to the second year of studies. First attempt pass rate is 86%, and close to 100% (565/566 students, 99.8%) following re-assessment the same day. 97% of participants enjoyed the course, 99% preferred peer-tutors to clinicians, 99% perceived teaching quality as "good" or "excellent", and felt they had sufficient practice. Course organisation was rated "good" or "excellent" by 91%. Each year 3-4 student projects have been published or presented internationally. The annual cost of providing the course is currently £15,594.70 (Eur 18

  14. Cerebral infarct in children aged zero to fifteen years Infarto cerebral em crianças de zero a quinze anos de idade

    Directory of Open Access Journals (Sweden)

    Thelma Ribeiro Noce

    2004-03-01

    Full Text Available Cerebral infarcts in children present peculiar characteristics either due to their diversity of causes or due to the unknown nature of the causes. The etiologies of cerebral infarct were reviewed in children from zero to 15 years old, attended at a tertiary hospital, in Ribeirão Preto (Brazil, from 1990 to 1997, adopting the modified Trial of ORG 10172 in Acute Stroke Treatment (TOAST criteria of classification; 1 - Atherosclerosis in large arteries; 2 - Cardioembolic; 3 - Occlusion of small vessels; 4 - Other etiologies; 5 - Undetermined cause. Thirty-nine children were included, 18 males and 21 females, aged 2 months to 15 years, mean age 5.67. The largest group, N=22 (56.4%, included children with ''other etiologies'', 7 of them aged under two years. The most common etiology was dehydration and septic shock leading to brain hypoperfusion and watershed infarcts. Nine (23% children had ''Undetermined etiology'', 7 (17,9% cardioembolic subtype and none had atherosclerosis. Laboratory improvement is needed for the large number of patients without a defined cause, and the high proportion of children with dehydration in the group with a determined cause emphasizes the need for preventive health actions among infants and children.Infartos cerebrais em crianças apresentam peculiaridades, como grande variedade de causas e alta freqüência sem etiologia definida. Foram revistos os diagnósticos etiológicos em crianças de zero a 15 anos, atendidas durante o ictus e com imagens cerebrais sugestivas de infarto, entre 1990 e 1997 em hospital terciário de Ribeirão Preto (SP. Adotou-se o critério de classificação modificado do Trial of ORG 10172 in Acute Stroke Treatment (TOAST: 1 - Arterioesclerose de grandes artérias, 2 - Cardioembólico, 3 - Oclusão de pequenos vasos, 4 - Outras etiologias, 5 - Não determinada. Trinta e nove crianças foram incluídas, 18 do sexo masculino e 21 do feminino, com idade variando entre 2 meses e 15 anos e m

  15. Assessment of Gastroenteric Viruses Frequency in a Children's Day Care Center in Rio De Janeiro, Brazil: A Fifteen Year Study (1994–2008)

    Science.gov (United States)

    Ferreira, Mônica Simões Rocha; Xavier, Maria da Penha Trindade Pinheiro; Tinga, Anna Carolina De Castro; Rose, Tatiana Lundgren; Fumian, Tulio Machado; Fialho, Alexandre Madi; de Assis, Rosane Maria; Costa, Filipe Aníbal Carvalho; de Oliveira, Solange Artimos; Leite, José Paulo Gagliardi; Miagostovich, Marize Pereira

    2012-01-01

    This 15-year study aimed to determine the role of the main viruses responsible for acute infantile gastroenteritis cases in a day care center in the city of Rio de Janeiro, Brazil. From 1994 to 2008, 539 fecal samples were obtained from 23 outbreaks as well as sporadic cases that occurred in this period. The detection of Rotavirus group A (RVA), norovirus (NoV) and astrovirus (AstV) was investigated both by classical and molecular methods of viral detection. RVA was detected by enzymatic immune assay and/or polyacrylamide gel electrophoresis and genotyped by using semi-nested multiplex PCR. NoV and AstV were subsequently tested by real time PCR in all RVA-negative samples and genotyped throughout genome sequencing. Three protocols for molecular characterization of NoV nucleotide sequencing were performed with the partial nucleotide sequencing of genomic regions known as region B (polymerase gen), C and D (capsid gen).Viruses were identified in 47.7% (257/539) of the cases, and the detection rates of RVA, NoV and AstV in16.1% (87/539), 33.4% (151/452), and 6.3% (19/301), respectively. Most gastroenteritis cases were reported in autumn and winter, although NoV presented a broader monthly distribution. Viruses' detection rates were significantly higher among children aged less than 24 months old, although NoV cases were detected in all age groups. RVA genotypes as G1P[8], G9P[8], G2P[4], G3P[8] and G1+G3P[8] and RVA was no longer detected after 2005. NoV characterization revealed genotypes variability circulating in the period as GI.2, GI.3, GI.8 GII.2, GII.3, GII.4, GII.4 variants 2001 and 2006b, GII.6, GII.7, GII.12 and GII.17. AstV genotypes 1, 2, 4 and 5 were also characterized. Those data demonstrate the impact of NoV infection in cases of infantile gastroenteritis, surpassing RVA infection responsible for high morbidity rate in children under five years old. PMID:22448271

  16. Heterotopic ossification and lessons learned from fifteen years at war: A review of therapy, novel research, and future directions for military and civilian orthopaedic trauma.

    Science.gov (United States)

    Hoyt, Benjamin W; Pavey, Gabriel J; Potter, Benjamin K; Forsberg, Jonathan A

    2018-04-01

    Heterotopic ossification, the formation of bone in soft tissues, is a common complication of the high-energy extremity trauma sustained in modern armed conflict. In the past 15years, military treatment facilities and aligned laboratories have been in a unique position to study and treat this process due to the high volume of patients with these injuries secondary to blast trauma. The devastating nature of these wounds has limited traditional therapeutic options, necessitating alternative solutions to prophylaxis and initial treatment producing substantial advances in modeling, prophylaxis, detection, and therapy. Specific developments include establishment of an animal model that reproduces the systemic and local tissue injury of blast injuries, the use of molecular assays and predictive modeling in clinical decision making, advances in early detection including Raman spectroscopy, and investigation of prophylactic and therapeutic pharmacotherapy targeting the molecular pathways of aberrant bone formation. In this review article, we will present the literature to date, ongoing studies, and future directions for investigation of heterotopic ossification, with a focus on military-specific research. Copyright © 2018. Published by Elsevier Inc.

  17. Fifteen Years (1993–2007 of Surface Freshwater Storage Variability in the Ganges-Brahmaputra River Basin Using Multi-Satellite Observations

    Directory of Open Access Journals (Sweden)

    Edward Salameh

    2017-03-01

    Full Text Available Surface water storage is a key component of the terrestrial hydrological and biogeochemical cycles that also plays a major role in water resources management. In this study, surface water storage (SWS variations are estimated at monthly time-scale over 15 years (1993–2007 using a hypsographic approach based on the combination of topographic information from Advance Spaceborne Thermal Emission and Reflection Radiometer (ASTER and Hydrological Modeling and Analysis Platform (HyMAP-based Global Digital Elevation Models (GDEM and the Global Inundation Extent Multi-Satellite (GIEMS product in the Ganges-Brahmaputra basin. The monthly variations of the surface water storage are in good accordance with precipitation from Global Precipitation Climatology Project (GPCP, river discharges at the outlet of the Ganges and the Brahmaputra, and terrestrial water storage (TWS from the Gravity Recovery And Climate Experiment (GRACE, with correlations higher than 0.85. Surface water storage presents a strong seasonal signal (~496 km3 estimated by GIEMS/ASTER and ~378 km3 by GIEMS/HyMAPs, representing ~51% and ~41% respectively of the total water storage signal and it exhibits a large inter-annual variability with strong negative anomalies during the drought-like conditions of 1994 or strong positive anomalies such as in 1998. This new dataset of SWS is a new, highly valuable source of information for hydrological and climate modeling studies of the Ganges-Brahmaputra river basin.

  18. Fifteen-year population attributable fractions and causal pies of risk factors for newly developed hepatocellular carcinomas in 11,801 men in Taiwan.

    Directory of Open Access Journals (Sweden)

    Shu-Fen Liao

    Full Text Available Development of hepatocellular carcinoma (HCC is a multi-factorial process. Chronic infections with hepatitis B virus (HBV and hepatitis C virus (HCV are important risk factors of HCC. Host factors, such as alcohol drinking, may also play a role. This study aims to provide a synthesis view on the development of HCC by examining multiple risk factors jointly and collectively. Causal-pie modeling technique was applied to analyze a cohort of 11,801 male residents (followed up for 15 years in Taiwan, during which a total of 298 incident HCC cases were ascertained. The rate ratios adjusted by age were further modeled by an additive Poisson regression. Population attributable fractions (PAFs and causal-pie weights (CPWs were calculated. A PAF indicates the magnitude of case-load reduction under a particular intervention scenario, whereas a CPW for a particular class of causal pies represents the proportion of HCC cases attributable to that class. Using PAF we observed a chance to reduce around 60% HCC risk moving from no HBV-related intervention to the total elimination of the virus. An additional ∼15% (or ∼5% reduction can be expected, if the HBV-related intervention is coupled with an HCV-related intervention (or an anti-drinking campaign. Eight classes of causal pies were found to be significant, including four dose-response classes of HBV (total CPW=52.7%, one independent-effect class of HCV (CPW=14.4%, one HBV-alcohol interaction class (CPW=4.2%, one HBV-HCV interaction class (CPW=1.7%, and one all-unknown class (CPW=27.0%. Causal-pie modeling for HCC helps clarify the relative importance of each viral and host factor, as well as their interactions.

  19. Fifteen-year population attributable fractions and causal pies of risk factors for newly developed hepatocellular carcinomas in 11,801 men in Taiwan.

    Science.gov (United States)

    Liao, Shu-Fen; Yang, Hwai-I; Lee, Mei-Hsuan; Chen, Chien-Jen; Lee, Wen-Chung

    2012-01-01

    Development of hepatocellular carcinoma (HCC) is a multi-factorial process. Chronic infections with hepatitis B virus (HBV) and hepatitis C virus (HCV) are important risk factors of HCC. Host factors, such as alcohol drinking, may also play a role. This study aims to provide a synthesis view on the development of HCC by examining multiple risk factors jointly and collectively. Causal-pie modeling technique was applied to analyze a cohort of 11,801 male residents (followed up for 15 years) in Taiwan, during which a total of 298 incident HCC cases were ascertained. The rate ratios adjusted by age were further modeled by an additive Poisson regression. Population attributable fractions (PAFs) and causal-pie weights (CPWs) were calculated. A PAF indicates the magnitude of case-load reduction under a particular intervention scenario, whereas a CPW for a particular class of causal pies represents the proportion of HCC cases attributable to that class. Using PAF we observed a chance to reduce around 60% HCC risk moving from no HBV-related intervention to the total elimination of the virus. An additional ∼15% (or ∼5%) reduction can be expected, if the HBV-related intervention is coupled with an HCV-related intervention (or an anti-drinking campaign). Eight classes of causal pies were found to be significant, including four dose-response classes of HBV (total CPW=52.7%), one independent-effect class of HCV (CPW=14.4%), one HBV-alcohol interaction class (CPW=4.2%), one HBV-HCV interaction class (CPW=1.7%), and one all-unknown class (CPW=27.0%). Causal-pie modeling for HCC helps clarify the relative importance of each viral and host factor, as well as their interactions.

  20. Carriage of Haemophilus influenzae in the oropharynx of young children and molecular epidemiology of the isolates after fifteen years of H. influenzae type b vaccination in Italy.

    Science.gov (United States)

    Giufrè, Maria; Daprai, Laura; Cardines, Rita; Bernaschi, Paola; Ravà, Lucilla; Accogli, Marisa; Raponi, Massimiliano; Garlaschi, Maria Laura; Ciofi degli Atti, Marta Luisa; Cerquetti, Marina

    2015-11-17

    Haemophilus influenzae is an important pathogen able to cause a wide spectrum of diseases in children. Colonization of the upper respiratory tract is a risk factor for developing disease. This study aimed to investigate the oropharyngeal carriage rate of H. influenzae in young children in two Italian cities, 15 years after H. influenzae type b (Hib) vaccination was introduced. Antibiotic resistant traits and genotypes of the colonizing H. influenzae isolates were investigated. Oropharyngeal swabs were obtained from 717 healthy children aged influenzae colonization were investigated. H. influenzae isolates from carriage were characterized by PCR capsular typing, ampicillin susceptibility testing, resistance-associated gene sequencing and multilocus sequence typing (MLST). For comparison purposes, 38 non-typeable H. influenzae (NTHi) isolates from invasive disease were genotyped by MLST. The overall H. influenzae carriage rate was 14.1% (101/717). Age, study site, presence of young siblings, and complete Hib vaccination status were independently associated with colonization. Of 101 isolates, 98 were NTHi, 2 were type e and 1 was type f. The overall ampicillin resistance rate was 15.8% (16/101). Resistance was mediated by TEM-1 β-lactamase production in half of isolates (n=8) or modifications in penicillin-binding protein (PBP) 3 in the other half (n=8). Several substitutions were discovered in PBP3 including the Asn526Lys change. Seventy-six different STs were identified among 98 NTHi isolates from carriage, with only 4 STs (ST12, ST57, ST238, ST1238) encompassing ≥ 3 isolates. Comparison of carriage and disease isolates found that several STs were shared between the two sources, although none of the major disease-associated STs were observed in carriage isolates. NTHi is the predominant serotype in carriage. The importance of monitoring both NTHi colonization rate and circulating genotypes should be emphasized in the era of the Hib conjugate vaccines. Copyright

  1. Efficacy of the seven feature, fifteen point histological scoring system and CD56 in interpretation of liver biopsies in persistent neonatal cholestasis: A five-year study

    Directory of Open Access Journals (Sweden)

    O H Radhika Krishna

    2014-01-01

    Full Text Available Context: Neonatal cholestasis (NC lasting more than 2 weeks affects one in 2500 live births. Extrahepatic biliary atresia (EHBA and idiopathic neonatal hepatitis account for about 70% of all cases of NC. Differentiating these two conditions is important as patient management is very different for both the conditions. Aims: To assess the usefulness of the seven-feature, 15-point histological scoring system in the interpretation of liver biopsy in NC and usefulness of immunostaining with CD56 (N-CAM in EHBA. Settings and Design: Retrospective study of 5 years′ duration at a pediatric referral institute, where the case load of NC is high and definitive surgery for EHBA is undertaken after histological confirmation. Materials and Methods: The study is of a 5-year duration conducted between June 2007 and May 2012. A total of 210 cases of NC were clinically diagnosed during this period. All the slides were reviewed with reference to a seven-feature, 15-point histological scoring system assessing its usefulness in the interpretation of liver biopsy in NC and utility of the immunohistochemical marker CD56 was also assessed as an aid in the characterization of bile ductular proliferation in EHBA. Statistical Analysis: Statistical analysis was performed and sensitivity and specificity of the histological scoring system for EHBA was analyzed. Results: Of the 210 liver biopsies reviewed using the scoring system, 122 cases were diagnosed as EHBA and 88 cases were diagnosed as other causes of NC. The overall sensitivity of this scoring system was 95.5%, specificity was 93.1% and diagnostic accuracy was 94.6%. Conclusions: The seven-feature, 15-point histological scoring system has good diagnostic accuracy in the interpretation of liver histology in NC as advanced histopathological findings even at younger age require immediate surgery. CD-56 is a useful marker in the assessment of bile ductular proliferation in EHBA.

  2. The epidemiology and clinical spectrum of melioidosis in a teaching hospital in a North-Eastern state of Malaysia: a fifteen-year review.

    Science.gov (United States)

    Zueter, AbdelRahman; Yean, Chan Yean; Abumarzouq, Mahmoud; Rahman, Zaidah Abdul; Deris, Zakuan Z; Harun, Azian

    2016-07-16

    Over the last two decades, many epidemiological studies were performed to describe risks and clinical presentations of melioidosis in endemic countries. We performed a retrospective analysis of 158 confirmed cases of melioidosis collected from medical records from 2001 to 2015 in Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia, in order to update the current status of melioidosis clinical epidemiology in this putatively high risk region of the country. Principal presentations in patients were lung infection in 65 (41.1 %), skin infection in 44 (27.8 %), septic arthritis/osteomyelitis in 20 (12.7 %) and liver infection in 19 (12.0 %). Bacteremic melioidosis was seen in most of patients (n = 121, 76.6 %). Focal melioidosis was seen in 124 (78.5 %) of patients and multi-focal melioidosis was reported in 45 (28.5 %) cases. Melioidosis with no evident focus was in 34 (21.5 %) patients. Fifty-four (34.2 %) patients developed septic shock. Internal organ abscesses and secondary foci in lungs and/or soft tissue were common. A total of 67 (41 %) cases presented during the monsoonal wet season. Death due to melioidosis was reported in 52 (32.9 %) patients, while relapses were occurred in 11 (7.0 %). Twelve fatal melioidosis cases seen in this study were directly attributed to the absence of prompt acute-phase treatment. Predisposing risk factors were reported in most of patients (n = 133, 84.2 %) and included diabetes (74.7 %), immune disturbances (9.5 %), cancer (4.4 %) and chronic kidney disease (11.4 %). On multivariate analysis, the only independent predictors of mortality were the presence of at least one co-morbid factor (OR 3.0; 95 % CI 1.1-8.4), the happening of septic shock (OR 16.5; 95 % CI 6.1-44.9) and age > 40 years (OR 6.47; 95 % CI 1.7-23.8). Melioidosis should be recognized as an opportunistic nonfatal infection for healthy person. Prompt early diagnosis and appropriate antibiotics administration and

  3. Trends of Mycobacterium bovis Isolation and First-Line Anti-tuberculosis Drug Susceptibility Profile: A Fifteen-Year Laboratory-Based Surveillance.

    Directory of Open Access Journals (Sweden)

    Miriam Bobadilla-del Valle

    2015-09-01

    Full Text Available Mycobacterium tuberculosis causes the majority of tuberculosis (TB cases in humans; however, in developing countries, human TB caused by M. bovis may be frequent but undetected. Human TB caused by M. bovis is considered a zoonosis; transmission is mainly through consumption of unpasteurized dairy products, and it is less frequently attributed to animal-to-human or human-to-human contact. We describe the trends of M. bovis isolation from human samples and first-line drug susceptibility during a 15-year period in a referral laboratory located in a tertiary care hospital in Mexico City.Data on mycobacterial isolates from human clinical samples were retrieved from the laboratory's database for the 2000-2014 period. Susceptibility to first-line drugs: rifampin, isoniazid, streptomycin (STR and ethambutol was determined. We identified 1,165 isolates, 73.7% were M. tuberculosis and 26.2%, M. bovis. Among pulmonary samples, 16.6% were M. bovis. The proportion of M. bovis isolates significantly increased from 7.8% in 2000 to 28.4% in 2014 (X(2trend, p<0.001. Primary STR resistance was higher among M. bovis compared with M. tuberculosis isolates (10.9% vs.3.4%, p<0.001. Secondary multidrug resistance (MDR rates were 38.5% and 34.4% for M. bovis and M. tuberculosis, respectively (p = 0.637. A rising trend of primary STR monoresistance was observed for both species (3.4% in 2000-2004 vs. 7.6% in 2010-2014; p = 0.02.There is a high prevalence and a rising trend of M. bovis isolates in our region. The proportion of pulmonary M. bovis isolates is higher than in previous reports. Additionally, we report high rates of primary anti-tuberculosis resistance and secondary MDR in both M. tuberculosis and M. bovis. This is one of the largest reports on drug susceptibility of M. bovis from human samples and shows a significant proportion of first-line anti-tuberculosis drug resistance.

  4. Fifteen years experience: Egyptian metabolic lab

    African Journals Online (AJOL)

    Ekram M. Fateen

    2014-08-20

    Aug 20, 2014 ... Abstract Background: Inborn errors of metabolism (IEM) are single gene disorders responsible for abnormalities in ... of inherited metabolic disorders in Egypt was very limited and diagnosed mainly on clinical suspi- cion. In 1995 ..... tomatic in newborns, but if left untreated it affects liver, kid- ney, bone, and ...

  5. The introduction of the 5-year impact factor : does it benefit statistics journals?

    NARCIS (Netherlands)

    van Nierop, Erjen

    In this paper, we investigate the effects of the introduction of 5-year impact factors. We collect impact factor data for all disciplines available in the Journal Citation Reports. For all these categories, we give insights into the relationship between the traditional 2-year impact factor and the

  6. Age at Introduction to Solid Foods and Child Obesity at 6 Years.

    Science.gov (United States)

    Barrera, Chloe M; Perrine, Cria G; Li, Ruowei; Scanlon, Kelley S

    2016-06-01

    Epidemiological evidence suggests that timing of introduction of solid foods may be associated with subsequent obesity, and the association may vary by whether an infant is breastfed or formula-fed. We included 1181 infants who participated in the Infant Feeding Practices Study II (IFPS II) and the Year 6 Follow Up (Y6FU) study. Data from IFPS II were used to calculate the primary exposure and timing of solid food introduction (obesity at 6 years of age (BMI ≥95th percentile). We used multivariable logistic regression to assess the association between timing of the introduction of solids and obesity at 6 years and test whether this association was modified by breastfeeding duration (breastfed for 4 months vs. not). Prevalence of obesity in our sample was 12.0%. The odds of obesity was higher among infants introduced to solids obesity. We found no interaction between breastfeeding duration and early solid food introduction and subsequent obesity. Timing of introduction of solid foods was not associated with child obesity at 6 years in this sample. Given the inconsistency in findings with other studies, further studies in larger populations may be needed.

  7. 1.0 INTRODUCTION In recent years, there ·. has been a shortfall in the

    African Journals Online (AJOL)

    g.raphical:analysis of continuous-time control systems~. ·. ·. :: Keywords: Simulation, Computer-aided learning, Continuous-time control · system. 1.0 INTRODUCTION. In recent years, there ·. has been a shortfall in the. ···number of students offering to. : . option in~ -the field . of Control. · Engineering_ at undergraduate.

  8. Introduction to Biological Investigations: A First-Year Experience in Experimental Design and Scientific Communication

    Science.gov (United States)

    Foote, Linda C.; Fitzpatrick, Kathleen A.

    2004-01-01

    Introduction to Biological Investigations is a course that was developed to introduce the scientific method through practical application. This active, student-centered experience fosters fundamental skills that promote creativity, critical thinking, and scientific-communication. The course has been well received by first-year students, and…

  9. Delayed introduction of solid feeding reduces child overweight and obesity at 10 years.

    Science.gov (United States)

    Seach, K A; Dharmage, S C; Lowe, A J; Dixon, J B

    2010-10-01

    The function that the timing of introduction of solid foods may have in the development of child obesity has not been adequately explored, either as a potential confounder of the relationship between breastfeeding and child obesity, or as an independent modifiable risk factor. To determine the association between infant feeding practices and child overweight/obesity. Six hundred and twenty subjects were recruited antenatally from 1990 to 1994. A total of 18 telephone interviews over the first 2 years of life recorded infant feeding practices. At mean age of 10 years, height and weight were measured for 307 subjects. Multiple logistic regression was used to determine whether infant feeding practices (duration of exclusive and any breastfeeding, and age at introduction of solid foods) were associated with odds of being overweight/obese (internationally age- and sex-standardized body mass index category) at age 10 years, after adjustment for confounders. Delayed introduction of solid foods was associated with reduced odds of being overweight/obese at age 10 years, after controlling for socioeconomic status, parental smoking and childcare attendance (adjusted odds ratio (aOR)=0.903 per week, 95% CI=0.841-0.970, P=0.005). Antenatal parental smoking was associated with overweight/obesity at age 10 years (aOR=3.178, 95% CI=1.643-6.147, P=0.001). Duration of exclusive or any breastfeeding was not associated with the outcome. Delayed introduction of solids is associated with reduced odds of child overweight/obesity. Wider promotion of current infant feeding guidelines could have a significant impact on the rates of child overweight and obesity.

  10. Invasion and Colonisation of a Tropical Stream by an Exotic Loricariid Fish: Indices of Gradual Displacement of the Native Common Pleco (Hypostomus punctatus) by the Red Fin Dwarf Pleco (Parotocinclus maculicauda) over Fifteen Years.

    Science.gov (United States)

    Mazzoni, Rosana; Costa da Silva, Raquel; Pinto, Míriam Plaza

    2015-01-01

    The introduction of invasive species represents a major threat to the integrity of stream-dwelling fish populations worldwide, and this issue is receiving increasing attention from scientists, in particular because of potential impact on biodiversity. In this study, we analysed the dispersal of an exotic loricariid fish the red fin dwarf pleco (Parotocinclus maculicauda) in a stream of the Atlantic Forest biome in coastal south-eastern Brazil and evaluated the effects of this invasion on the native loricariid common pleco (Hypostomus punctatus). Specimens were collected at eight sites located along the course of the stream over a 15-year period. The distribution and density of the two species were determined by the Successive Removal Method. The introduction of P. maculicauda occurred in the medium sector of the stream, and during the course of the study, the species dispersed to new sites further upstream. By the end of the study, it was found at all points upstream from the original site. Hypostomus punctatus was registered at all sample sites both before and after the introduction of P. maculicauda, but its density decreased at all upstream sites after the arrival of the exotic species. Our analysis shows that colonisation by P. maculicauda seems to have a negative effect on H. punctatus densities. The maintenance of H. punctatus densities at the sites not colonised by P. maculicauda reinforces the conclusion that the colonisation of the stream by the exotic species had deleterious effects on the density of the resident H. punctatus populations, either by direct or indirect action.

  11. Effects of atmospheric VPD, plant canopies, and low-water years on leaf stomatal conductance and photosynthetic water use efficiency in fifteen potential crop species for use in arid environments

    Science.gov (United States)

    Lue, A.; Jasoni, R. L.; Arnone, J.

    2011-12-01

    When evaluating the potential for growing alternative crop species in arid environments, high vapor pressure deficits (VPDs) that could potentially inhibit crop productivity by limiting stomatal conductance and CO2 uptake must be considered. The objective of this study was to quantify the effects of VPD and irrigation levels on leaf stomatal conductance (gs) and photosynthetic water use efficiency (PWUE) for a range of alternative crop species for aridland agriculture. We evaluated fifteen alternative crops in a field trial in the northern Nevada Walker River Basin. Plots of each species were subjected to two irrigation treatments, 4 and 2 acre-feet per growing season, to simulate normal-year and dry-year irrigation levels. We quantified gs and photosynthesis (A) under decreasing relative humidity (RH) (increasing VPDs) in 10% increments, from about 75% to 2%. About seventeen leaves per species were measured throughout the 2010 growing season over eleven days of samplings. Canopy air temperature and RH were logged in experimental plots to calculate diel and seasonal patterns in canopy VPD. Volumetric water content was also collected to quantify the effects of irrigation treatments on soil moisture and leaf gas exchange. Species varied in their gs and PWUE responses to increasing VPD. Stomatal conductance (gs) of leaves of all species generally increased initially as RH was lowered but then decreased at differing rates as RH dropped further. Average gs (across all measurement VPDs), maximum gs, maximum PWUE, and corresponding VPDs differed among species and between irrigation treatments. Some species (Medicago sativa, Leymus racemosus) showed higher gs across the range of measurement VPDs than other species (Bothrichloa ischaemum, Sorghastrum nutans), while some species exhibited maximum gs and maximum PWUE at higher VPDs (Erograstis tef, Calamovilfa longifolia) than other species (Leymus cinereus, Sorghastrum nutans). These results suggest that some species may

  12. Sustained Effectiveness of the Maternal Pertussis Immunization Program in England 3 Years Following Introduction

    Science.gov (United States)

    Amirthalingam, Gayatri; Campbell, Helen; Ribeiro, Sonia; Fry, Norman K.; Ramsay, Mary; Miller, Elizabeth; Andrews, Nick

    2016-01-01

    The effectiveness of maternal immunization in preventing infant pertussis was first demonstrated in England, 1 year after the program using diphtheria–tetanus–5-component acellular pertussis–inactivated polio vaccine (dT5aP-IPV) was introduced in 2012. Vaccine effectiveness against laboratory-confirmed pertussis has been sustained >90% in the 3 years following its introduction, despite changing to another acellular vaccine with different antigen composition. Consistent with this, disease incidence in infants immunization is retained in infants who received their first dose of the primary series. There is no longer evidence of additional protection from maternal vaccination after the third infant dose. Although numbers are small and ongoing assessment is required, there is no evidence of increased risk of disease after primary immunization in infants whose mothers received maternal vaccination. PMID:27838678

  13. Higher Tetanus Toxoid Immunity 2 Years After PsA-TT Introduction in Mali.

    Science.gov (United States)

    Basta, Nicole E; Borrow, Ray; Berthe, Abdoulaye; Onwuchekwa, Uma; Dembélé, Awa Traoré Eps; Almond, Rachael; Frankland, Sarah; Patel, Sima; Wood, Daniel; Nascimento, Maria; Manigart, Olivier; Trotter, Caroline L; Greenwood, Brian; Sow, Samba O

    2015-11-15

    In 2010, mass vaccination with a then-new meningococcal A polysaccharide-tetanus toxoid protein conjugate vaccine (PsA-TT, or MenAfriVac) was undertaken in 1- to 29-year-olds in Bamako, Mali. Whether vaccination with PsA-TT effectively boosts tetanus immunity in a population with heterogeneous baseline tetanus immunity is not known. We assessed the impact of PsA-TT on tetanus toxoid (TT) immunity by quantifying age- and sex-specific immunity prior to and 2 years after introduction. Using a household-based, age-stratified design, we randomly selected participants for a prevaccination serological survey in 2010 and a postvaccination survey in 2012. TT immunoglobulin G (IgG) antibodies were quantified and geometric mean concentrations (GMCs) pre- and postvaccination among all age groups targeted for vaccination were compared. The probability of TT IgG levels ≥0.1 IU/mL (indicating short-term protection) and ≥1.0 IU/mL (indicating long-term protection) by age and sex was determined using logistic regression models. Analysis of 793 prevaccination and 800 postvaccination sera indicated that while GMCs were low pre-PsA-TT, significantly higher GMCs in all age-sex strata were observed 2 years after PsA-TT introduction. The percentage with short-term immunity increased from 57.1% to 88.4% (31.3-point increase; 95% confidence interval [CI], 26.6-36.0;, P tetanus immunity. © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America.

  14. [Cushing's syndrome: clinical study of fifteen cases].

    Science.gov (United States)

    Calvo Romero, J M; Morales Pérez, F; Alvarez Barreiro, J A; Diaz Pérez de Madrid, J

    1998-05-01

    To study the epidemiological and clinical features and diagnostic tests of Cushing's syndrome (CS) of non-iatrogenic etiology, because of there are few similar studies in the last ten years. Fifteen cases of CS were diagnosed from 1992 to 1997 at our hospital. We describe the epidemiological, clinical, biochemical, radiologic, therapeutic and evolutive characteristics. Both diabetes mellitus and hypertension were observed in 40% of patients. The frequency of etiologies was: Cushing's disease, 66.6%; ectopic ACTH syndrome, 13.3%; adrenal adenoma, 6.6%; adrenal carcinoma, 6.6%; and undiagnosed, 6.6%. The 24-hour urine free cortisol (UFC) and the overnight 1 mg oral dexamethasone suppression test yielded 93.3 and 100% diagnostic sensitivity for CS, respectively. The overnight 8 mg oral dexamethasone suppression test, the metyrapone test and the 7 mg intravenous dexmethasone test had 75, 50 and 60% diagnostic sensitivity for Cushing's disease, respectively. Ketoconazole treatment had success in to normalize the 24-hour UFC in all patients, except for the case of adrenal carcinoma. The Cushing's disease was the most common form of CS. The 24-hour UFC and overnight 1 mg oral dexamethasone suppression test were good screening studies. Ketoconazole was successful in normalizing the adrenal cortex function.

  15. Reflecting upon 10 years of geoengineering research: Introduction to the Crutzen + 10 special issue

    Science.gov (United States)

    Boettcher, Miranda; Schäfer, Stefan

    2017-03-01

    Ten years ago, Nobel laureate Paul Crutzen called for research into the possibility of reflecting sunlight away from Earth by injecting sulfur particles into the stratosphere. Across academic disciplines, Crutzen's intervention caused a surge in interest in and research on proposals for what is often referred to as "geoengineering"—an unbounded set of heterogeneous proposals for intentionally intervening into the climate system to reduce the risks of climate change. To mark the 10-year anniversary of the publication of Paul Crutzen's seminal essay, this special issue reviews the developments in geoengineering research since Crutzen's intervention and reflects upon possible future directions that geoengineering research may take. In this introduction, we briefly outline the arguments made in Paul Crutzen's (2006) contribution and describe the key developments of the past 10 years. We then proceed to give an overview of some of the central issues in current discussions on geoengineering, and situate the contributions to this special issue within them. In particular, we contend that geoengineering research is characterized by an orientation toward speculative futures that fundamentally shapes how geoengineering is entering the collective imagination of scientists, policymakers, and publics, and a mode of knowledge production that recognizes the risks that may result from new knowledge and that struggles with its own socio-political dimensions.

  16. Sustained Effectiveness of the Maternal Pertussis Immunization Program in England 3 Years Following Introduction.

    Science.gov (United States)

    Amirthalingam, Gayatri; Campbell, Helen; Ribeiro, Sonia; Fry, Norman K; Ramsay, Mary; Miller, Elizabeth; Andrews, Nick

    2016-12-01

    The effectiveness of maternal immunization in preventing infant pertussis was first demonstrated in England, 1 year after the program using diphtheria-tetanus-5-component acellular pertussis-inactivated polio vaccine (dT5aP-IPV) was introduced in 2012. Vaccine effectiveness against laboratory-confirmed pertussis has been sustained >90% in the 3 years following its introduction, despite changing to another acellular vaccine with different antigen composition. Consistent with this, disease incidence in infants Vaccine effectiveness against infant deaths was estimated at 95% (95% confidence interval, 79%-100%). Additional protection from maternal immunization is retained in infants who received their first dose of the primary series. There is no longer evidence of additional protection from maternal vaccination after the third infant dose. Although numbers are small and ongoing assessment is required, there is no evidence of increased risk of disease after primary immunization in infants whose mothers received maternal vaccination. © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America.

  17. Introduction of microsurgery in Vietnam by a charitable organization: a 15-year experience.

    Science.gov (United States)

    Merrell, J Craig; Tien, Nguyen Viet; Son, Nguyen Tai; An, Luu Ngoc; Sellers, Daniel; Russell, Robert; Manktelow, Ralph; Wei, Fu-Chan; Orgill, Dennis P

    2007-04-01

    Microsurgical procedures, although equipment- and labor-intensive, allow efficient treatment of selected soft-tissue, bone, and peripheral nerve defects. The precise surgical skills required and the high equipment and institutional costs have been deterrents to initiating programs in developing countries. The authors report their 15-year international effort in facilitating the development of microsurgical techniques in Vietnam. The authors reviewed their educational, logistical, and operative experience from 11 Operation Smile International missions to Vietnam and the microsurgical procedures performed independently by Vietnamese surgeons at the Central Military Hospital 108 in Hanoi. Over 15 years, Operation Smile International missions to Vietnam performed 108 free tissue transfer operations with 15 peripheral nerve transfer procedures and 143 nonmicrosurgical reconstructive operations. Visiting surgeons with specialized expertise taught facial reanimation, flap prefabrication, and perforator flaps. During this same period, Vietnamese surgeons became facile with microsurgical techniques and independently performed a wide array of these procedures in the institutions visited. Vietnamese surgeons have organized microsurgery divisions within some hospital departments and now teach microsurgical techniques. Repeated missions allowed for patient follow-up, staged procedures, educational exchange, and quality control. Several Vietnamese surgeons have traveled abroad to obtain additional training and have set up training programs in other areas of Vietnam. Charitable organizations can help surgeons in developing countries master complex microsurgical techniques through short-term medical missions, donation of equipment and supplies, and the encouragement of institutional support. A continuing education program, including local conferences, microsurgical laboratory training facilities, and study abroad, can aid this introduction.

  18. Kudzu eradication trials testing fifteen herbicides

    Science.gov (United States)

    James H. Miller

    1986-01-01

    Two studies examined herbicide treatments for controlling kudzu [Pueraria lobata (Willd.) Ohwi]. In one study, fifteen herbicides were tested at 1 or 2 rates at 5 locations. Treatments and re-treatments occurred over a 2-yr period. The most effective herbicides were picloram pellets (4.7 and 5.8 lb ai/a), tebuthiuron pellets (6 lb ai/a), and picloram...

  19. Effects of Age and Stimulus Material on Character Introductions of Swedish-Speaking Four- to Six-Year-Olds

    Science.gov (United States)

    Lindgren, Josefin

    2018-01-01

    This study investigates effects of age on character introductions in the oral narratives of seventy-two monolingual Swedish-speaking four- to six-year-olds, comparing results from the Multilingual Assessment Instrument for Narratives (MAIN; Gagarina "et al.," 2012, 2015), and the Edmonton Narrative Norms Instrument (ENNI; Schneider…

  20. Reflecting on 25 Years of Teaching, Researching, and Textbook Writing for Introduction to Management: An Essay with Some Lessons Learned

    Science.gov (United States)

    Dyck, Bruno

    2017-01-01

    This essay describes innovations made and lessons learned while teaching introduction to management courses during a 25-year career. The essay describes how teaching two approaches to management increases students' critical and ethical thinking, and reverses the tendency for business students to become increasingly materialistic and…

  1. Fish introductions in the former Soviet Union: The Sevan trout (Salmo ischchan - 80 years later.

    Directory of Open Access Journals (Sweden)

    Wiesław Bogdanowicz

    Full Text Available The Soviet Union played the leading role in fish introductions in Eurasia. However, only 3% of all introductions prior to 1978 gave a commercial benefit. One of the noteworthy examples appears to be the Sevan trout (Salmo ischchan Kessler, 1877-an endemic salmonid of Lake Sevan in Armenia. This species has been introduced to Kirghizstan, Kazakhstan, and Uzbekistan, however, only the Kirghiz population has persisted in relatively high numbers. In this paper we provide the first extensive molecular study of S. ischchan using samples from the native population from Lake Sevan and three hatcheries in Armenia, as well as from the population introduced to Lake Issyk Kul in Kirghizstan. The Kirghiz population has been isolated since the introductions took place in 1930 and 1936. Our results, based on 11 nuclear microsatellites and a 905 bp fragment of the mitochondrial control region suggest that hatcheries have maintained genetic variability by way of ongoing translocations of individuals from Lake Sevan. Simultaneously, significant Garza-Williamson M-values suggest that bottlenecks could have reduced the genetic variability of the wild populations in the past. This hypothesis is supported by historical data, indicating highly manipulated water-level regulations and poaching as two main factors that dramatically impact fish abundance in the lake. On the other hand, a similar situation has been observed in Kirghizstan, but this population likely rebounded from small population size faster than the other populations examined. The Kirghiz population is significantly genetically differentiated from the other groups and have morphological features and biological attributes not observed in the source population. Genetic data imply that the effective population size in the native population is lower than that found in the introduced population, suggesting that some active protection of the Lake Sevan population may be needed urgently.

  2. Fish introductions in the former Soviet Union: The Sevan trout (Salmo ischchan) - 80 years later.

    Science.gov (United States)

    Bogdanowicz, Wiesław; Rutkowski, Robert; Gabrielyan, Bardukh K; Ryspaev, Akylbek; Asatryan, Anzhela N; Mkrtchyan, Jon A; Bujalska, Barbara M

    2017-01-01

    The Soviet Union played the leading role in fish introductions in Eurasia. However, only 3% of all introductions prior to 1978 gave a commercial benefit. One of the noteworthy examples appears to be the Sevan trout (Salmo ischchan Kessler, 1877)-an endemic salmonid of Lake Sevan in Armenia. This species has been introduced to Kirghizstan, Kazakhstan, and Uzbekistan, however, only the Kirghiz population has persisted in relatively high numbers. In this paper we provide the first extensive molecular study of S. ischchan using samples from the native population from Lake Sevan and three hatcheries in Armenia, as well as from the population introduced to Lake Issyk Kul in Kirghizstan. The Kirghiz population has been isolated since the introductions took place in 1930 and 1936. Our results, based on 11 nuclear microsatellites and a 905 bp fragment of the mitochondrial control region suggest that hatcheries have maintained genetic variability by way of ongoing translocations of individuals from Lake Sevan. Simultaneously, significant Garza-Williamson M-values suggest that bottlenecks could have reduced the genetic variability of the wild populations in the past. This hypothesis is supported by historical data, indicating highly manipulated water-level regulations and poaching as two main factors that dramatically impact fish abundance in the lake. On the other hand, a similar situation has been observed in Kirghizstan, but this population likely rebounded from small population size faster than the other populations examined. The Kirghiz population is significantly genetically differentiated from the other groups and have morphological features and biological attributes not observed in the source population. Genetic data imply that the effective population size in the native population is lower than that found in the introduced population, suggesting that some active protection of the Lake Sevan population may be needed urgently.

  3. Femoral Component Revision with Use of Impaction Bone-Grafting and a Cemented Polished Stem: A Concise Follow-up, at Fifteen to Twenty Years, of a Previous Report*

    NARCIS (Netherlands)

    Te Stroet, M.A.; Gardeniers, J.W.M.; Verdonschot, N.J.; Rijnen, W.H.C.; Slooff, T.J.J.H.; Schreurs, B.W.

    2012-01-01

    We previously reported our results for thirty-three consecutive femoral component revisions with impaction bone-grafting, performed with the X-change femoral revision system and a cemented polished Exeter stem, at a minimum of eight years of follow-up. The present updated study shows the results

  4. Design, implementation and evaluation of a community health training program in an integrated problem-based medical curriculum: a fifteen-year experience at the University of Geneva Faculty of Medicine

    Directory of Open Access Journals (Sweden)

    Philippe Chastonay

    2012-06-01

    Full Text Available Background: In the literature the need for relevance in medical education and training has been stressed. In the last 40 years medical schools have been challenged to train doctors competent to respond to community health needs. In the mid-90s the University of Geneva Faculty of Medicine introduced an integrated medical curriculum. In this initiative a particular emphasis was put in introducing a 6-year longitudinal and multidisciplinary Community Health Program (CHP. Objectives: The aims of the present article are to describe the conception, elaboration and implementation of the CHP as well as its evolution over 15 years and the evaluation of its outcomes. Methods: The CHP was at its origin elaborated by a small group of highly motivated teachers and later on developed by a multi-disciplinary group of primary care physicians, epidemiologists, public health and bio-ethics specialists, occupational health professionals, lawyers and historians. Evaluation of the program outcomes included educational innovations, new developments of the curriculum and interactions between students and the community. Results: The CHP learning objectives and teaching modalities were defined by the multi-disciplinary group in consensus meetings which triggered a collaborative spirit among teachers and facilitated further developments. The evaluation procedures allowed the monitoring of students’ satisfaction which remained high over the years, students’ active participation which decreased over time and success at certifying exams which was globally as good as in basic life sciences. The evaluation also assessed outcomes such as educational innovations, new developments of the curriculum and interactions between students and the community. Conclusion: As suggested in the literature, our experience shows that the students’ direct exposure and practice in the community health environment is an effective training approach to broaden students’ education by

  5. Design, implementation and evaluation of a community health training program in an integrated problem-based medical curriculum: a fifteen-year experience at the University of Geneva Faculty of Medicine

    Science.gov (United States)

    Chastonay, Philippe; Vu, Nu Viet; Humair, Jean-Paul; Mpinga, Emmanuel Kabengele; Bernheim, Laurent

    2012-01-01

    Background In the literature the need for relevance in medical education and training has been stressed. In the last 40 years medical schools have been challenged to train doctors competent to respond to community health needs. In the mid-90s the University of Geneva Faculty of Medicine introduced an integrated medical curriculum. In this initiative a particular emphasis was put in introducing a 6-year longitudinal and multidisciplinary Community Health Program (CHP). Objectives The aims of the present article are to describe the conception, elaboration and implementation of the CHP as well as its evolution over 15 years and the evaluation of its outcomes. Methods The CHP was at its origin elaborated by a small group of highly motivated teachers and later on developed by a multi-disciplinary group of primary care physicians, epidemiologists, public health and bio-ethics specialists, occupational health professionals, lawyers and historians. Evaluation of the program outcomes included educational innovations, new developments of the curriculum and interactions between students and the community. Results The CHP learning objectives and teaching modalities were defined by the multi-disciplinary group in consensus meetings which triggered a collaborative spirit among teachers and facilitated further developments. The evaluation procedures allowed the monitoring of students’ satisfaction which remained high over the years, students’ active participation which decreased over time and success at certifying exams which was globally as good as in basic life sciences. The evaluation also assessed outcomes such as educational innovations, new developments of the curriculum and interactions between students and the community. Conclusion As suggested in the literature, our experience shows that the students’ direct exposure and practice in the community health environment is an effective training approach to broaden students’ education by offering them a community

  6. Design, implementation and evaluation of a community health training program in an integrated problem-based medical curriculum: a fifteen-year experience at the University of Geneva Faculty of Medicine.

    Science.gov (United States)

    Chastonay, Philippe; Vu, Nu Viet; Humair, Jean-Paul; Mpinga, Emmanuel Kabengele; Bernheim, Laurent

    2012-01-01

    In the literature the need for relevance in medical education and training has been stressed. In the last 40 years medical schools have been challenged to train doctors competent to respond to community health needs. In the mid-90s the University of Geneva Faculty of Medicine introduced an integrated medical curriculum. In this initiative a particular emphasis was put in introducing a 6-year longitudinal and multidisciplinary Community Health Program (CHP). The aims of the present article are to describe the conception, elaboration and implementation of the CHP as well as its evolution over 15 years and the evaluation of its outcomes. The CHP was at its origin elaborated by a small group of highly motivated teachers and later on developed by a multi-disciplinary group of primary care physicians, epidemiologists, public health and bio-ethics specialists, occupational health professionals, lawyers and historians. Evaluation of the program outcomes included educational innovations, new developments of the curriculum and interactions between students and the community. The CHP learning objectives and teaching modalities were defined by the multi-disciplinary group in consensus meetings which triggered a collaborative spirit among teachers and facilitated further developments. The evaluation procedures allowed the monitoring of students' satisfaction which remained high over the years, students' active participation which decreased over time and success at certifying exams which was globally as good as in basic life sciences. The evaluation also assessed outcomes such as educational innovations, new developments of the curriculum and interactions between students and the community. As suggested in the literature, our experience shows that the students' direct exposure and practice in the community health environment is an effective training approach to broaden students' education by offering them a community perspective of health and disease.

  7. Fifteen-year results of a randomized prospective trial of hyperfractionated chest wall irradiation versus once-daily chest wall irradiation after chemotherapy and mastectomy for patients with locally advanced noninflammatory breast cancer

    International Nuclear Information System (INIS)

    Buchholz, Thomas A.; Strom, Eric A.; Oswald, Mary Jane; Perkins, George H.; Oh, Julia; Domain, Delora; Yu, Tse-Kuan; Woodward, Wendy A.; Tereffe, Welela; Singletary, S. Eva; Thomas, Eva; Buzdar, Aman U.; Hortobagyi, Gabriel N.; McNeese, Marsha D.

    2006-01-01

    Purpose: To analyze the results of a Phase III clinical trial that investigated whether a hyperfractionated radiotherapy (RT) schedule could reduce the risk of locoregional recurrence in patients with locally advanced breast cancer treated with chemotherapy and mastectomy. Methods and Materials: Between 1985 and 1989, 200 patients with clinical Stage III noninflammatory breast cancer were enrolled in a prospective study investigating neoadjuvant and adjuvant chemotherapy. Of the 179 patients treated with mastectomy after neoadjuvant chemotherapy, 108 participated in a randomized component of the trial that compared a dose-escalated, hyperfractionated (twice-daily, b.i.d.) chest wall RT schedule (72 Gy in 1.2-Gy b.i.d. fractions) with a once-daily (q.d.) schedule (60 Gy in 2-Gy q.d. fractions). In both arms of the study, the supraclavicular fossa and axillary apex were treated once daily to 50 Gy. The median follow-up period was 15 years. Results: The 15-year actuarial locoregional recurrence rate was 7% for the q.d. arm and 12% for the b.i.d. arm (p = 0.36). The rates of severe acute toxicity were similar (4% for q.d. vs. 5% for b.i.d.), but moist desquamation developed in 42% of patients in the b.i.d. arm compared with 28% of the patients in the q.d. arm (p = 0.16). The 15-year actuarial rate of severe late RT complications did not differ between the two arms (6% for q.d. vs. 11% for b.i.d., p = 0.54). Conclusion: Although the sample size of this study was small, we found no evidence that this hyperfractionation schedule of postmastectomy RT offered a clinical advantage. Therefore, we have concluded that it should not be further studied in this cohort of patients

  8. Isolation and characterization of fifteen polymorphic microsatellite ...

    Indian Academy of Sciences (India)

    amplification in two other mealybug species. J. Genet. 91, e75–e78. Online only: http://www.ias.ac.in/jgenet/OnlineResources/91/e75.pdf]. Introduction. The citrus mealybug, Planococcus citri (Risso) is a cos- mopolitan and polyphagous insect pest mainly of subtrop- ical fruit trees under Mediterranean climate conditions and.

  9. Genetic structure of introduced populations: 120-year-old DNA footprint of historic introduction in an insular small mammal population

    Science.gov (United States)

    Simpson, Siobhan; Blampied, Nick; Peniche, Gabriela; Dozières, Anne; Blackett, Tiffany; Coleman, Stephen; Cornish, Nina; Groombridge, Jim J

    2013-01-01

    Wildlife populations have been introduced to new areas by people for centuries, but this human-mediated movement can disrupt natural patterns of genetic structure by altering patterns of gene flow. Insular populations are particularly prone to these influences due to limited opportunities for natural dispersal onto islands. Consequently, understanding how genetic patterns develop in island populations is important, particularly given that islands are frequently havens for protected wildlife. We examined the evolutionary origins and extent of genetic structure within the introduced island population of red squirrels (Sciurus vulgaris) on the Channel Island of Jersey using mitochondrial DNA (mtDNA) control region sequence and nuclear microsatellite genotypes. Our findings reveal two different genetic origins and a genetic architecture reflective of the introductions 120 years ago. Genetic structure is marked within the maternally inherited mtDNA, indicating slow dispersal of female squirrels. However, nuclear markers detected only weak genetic structure, indicating substantially greater male dispersal. Data from both mitochondrial and nuclear markers support historic records that squirrels from England were introduced to the west of the island and those from mainland Europe to the east. Although some level of dispersal and introgression across the island between the two introductions is evident, there has not yet been sufficient gene flow to erase this historic genetic “footprint.” We also investigated if inbreeding has contributed to high observed levels of disease, but found no association. Genetic footprints of introductions can persist for considerable periods of time and beyond traditional timeframes of wildlife management. PMID:23532702

  10. A fifteen year experience of total thyroidectomy for the management ...

    African Journals Online (AJOL)

    Tracheostomy was required in 35 (5.8%) patients but none was permanent. Conclusion: Total thyroidectomy is a relatively safe treatment option for patients who have simple multinodular goitre. It provides a permanent cure with a low postoperative morbidity risk. The burden of replacement l-thyroxine needs to be discussed ...

  11. Fifteen years of the Chinese Continental Scientific Drilling Program

    Science.gov (United States)

    Xu, Zhiqin; Yang, Jingsui; Wang, Chengshan; An, Zhisheng; Li, Haibing; Wang, Qin; Su, Dechen

    2017-05-01

    Continental scientific drilling can be regarded as a telescope into the Earth's interior because it provides process insight and uncompromised samples of rocks, fluids, and even sampled from the deep biosphere from the Earth's surface to great depths. As one of the three founding members of the International Continental Scientific Drilling Program (ICDP), ICDP China has made great achievements in many scientific drilling-related research fields. Based on the ICDP participation it attracted global attention of scientists and set up not only the Chinese Continental Scientific Drilling (CCSD) Program in 2001 but also a growing number of ambitious drilling projects in the country. The 5158 m deep borehole of the CCSD project at Donghai County in the Sulu ultrahigh-pressure metamorphic terrain demonstrates that large amounts of crustal rocks of the South China Block have been subducted to at least 120 km, followed by rapid uplift. After successful completion of drilling at Donghai, several continental scientific drilling projects were conducted with funding of the Chinese government and partially with support of ICDP, resulting in a total drilling depth of more than 35 000 m. These projects encompass the Continental Environmental Scientific Drilling Program of China, the Scientific Drilling Project of Wenchuan Earthquake Fault Zone, the Continental Scientific Drilling Project of Cretaceous Songliao Basin, and the Program of Selected Continental Scientific Drilling and Experiments. On the occasion of the 20th anniversary of the ICDP and the 15th anniversary of the CCSD Program, this paper reviews the history and major progress of the CCSD Program.

  12. CANDU fuel - fifteen years of power reactor experience

    International Nuclear Information System (INIS)

    Fanjoy, G.R.; Bain, A.S.

    1977-01-01

    CANDU (Canada Deuterium Uranium) fuel has operated in power reactors since 1962. Analyses of performance statistics, supplemented by examinations of fuel from power reactors and experimental loops have yielded: (a) A thorough understanding of the fundamental behaviour of CANDU fuel. (b) Data showing that the predicted high utilization of uranium has been achieved. Actual fuelling costs in 1976 at the Pickering Generating Station are 1.2 m$/kWh (1976 Canadian dollars) with the simple oncethrough natural-UO 2 fuel cycle. (c) Criteria for operation, which have led to the current very low defect rate of 0.03% of all assemblies and to ''CANLUB'' fuel, which has a graphite interlayer between the fuel and sheath to reduce defects on power increases. (d) Proof that the short length (500 mm), collapsible cladding features of the CANDU bundle are successful and that the fuel can operate at high-power output (current peak outer-element linear power is 58 +- 15% kW/m). Involvement by the utility in all stages of fuel development has resulted in efficient application of this fundamental knowledge to ensure proper fuel specifications, procurement, scheduling into the reactor and feedback to developers, designers and manufacturers. As of mid-1976 over 3 x 10 6 individual elements have been built in a well-estabilished commercially competitive fuel fabrication industry and over 2 x 10 6 elements have been irradiated. Only six defects have been attributed to faulty materials or fabrication, and the use of high-density UO 2 with low-moisture content precluded defects from hydrogen contamination and densification. Development work on UO 2 and other fuel cycles (plutonium and thorium) is continuing, and, because CANDU reactors use on-power fuelling, bundles can be inserted into power reactors for testing. Thus new fuel designs can be quickly adopted to ensure that the CANDU system continues to provide low-cost energy with high reliability

  13. Implementing CBM: SQL-Tutor after Fifteen Years

    Science.gov (United States)

    Mitrovic, Antonija; Ohlsson, Stellan

    2016-01-01

    SQL-Tutor is the first constraint-based tutor. The initial conference papers about the system were published in 1998 (Mitrovic 1998a, 1998b, 1998c), with an "IJAIED" paper published in 1999 (Mitrovic and Ohlsson, "International Journal Artificial Intelligence in Education," 10(3-4), 238-256, 1999). We published another…

  14. Fifteen years experience: Egyptian metabolic lab | Fateen | Egyptian ...

    African Journals Online (AJOL)

    This study shows the most common diagnosed inherited inborn errors of metabolism among the Egyptian population. ... In 1995, The Biochemical Genetics Unit at The National Research Centre has been established as a part of The Human Genetics Department and later on in 2003 it was developed into The Biochemical ...

  15. CANDU fuel - fifteen years of power reactor experience

    International Nuclear Information System (INIS)

    Fanjoy, G.R.; Bain, A.S.

    1977-05-01

    Analyses of performance statistics, supplemented by examinations of fuel from power reactors and experimental loops have yielded: (a) a thorough understanding of the fundamental behaviour of CANDU fuel; (b) data showing that the predicted high utilization of uranium has been achieved; (c) criteria for operation, which have led to the current very low defect rate of 0.03% of all assemblies and to 'CANLUB' fuel, which has a graphite interlayer between the fuel and sheath to reduce defects on power increases; (d) proof that the short length (500 mm), collapsible cladding features of the CANDU bundle are successful and that the fuel can operate at high-power output (current peak outer-element linear power is 58 +- 15% kW/m). As of mid-1976 over 3 x 10 6 individual elements have been built and over 2 x 10 6 elements have been irradiated. Only six defects have been attributed to faulty materials or fabrication, and the use of high-density UO 2 with low-moisture content precluded defects from hydrogen contamination and densification

  16. Fifteen years medical information sciences: the Amsterdam curriculum

    NARCIS (Netherlands)

    Jaspers, Monique W.; Fockens, Paul; Ravesloot, Jan H.; Limburg, Martien; Abu-Hanna, Ameen

    2004-01-01

    Objectives: To inform the medical informatics community on the rational, goals, evolution and present contents of the Medical Information Sciences program of the University of Amsterdam and our achievements. Methods: We elaborate on the history of our program, the philosophy, contents and

  17. Chernobyl, fifteen years after; Tchernobyl, 15 ans apres

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-04-01

    This work has been constituted around four questions: the future of the Chernobyl site, the damaged reactor, and the sarcophagus around it; the health consequences of the accident on the persons that have worked on the damaged reactor and on the population in the countries the most exposed to fallout,; the situation of contaminated territories around the power plant and their management today; the last question concerns especially the France with the consequences of the radioactive cloud and what we know about the health risks induced by this event. (N.C.)

  18. Fifteen Years of Democracy, 1999-2014: Reflections on Nigeria's ...

    African Journals Online (AJOL)

    DR Nneka

    A lot of effort has been deployed in attracting foreign investments alongside the reduction of the role of the ..... goals of restructuring the federation and the formulae for passing out oil profits. The key issue of federalism has .... Corruption is still the stock-in-trade of Nigerian democracy, rooted in the centralized, clientelistic ...

  19. Fifteen Fine Years of School Construction Progress, 1950-1965.

    Science.gov (United States)

    Milwaukee Public Schools, WI.

    A progress report reviews the Milwaukee School Board's continuous program of acquiring sites and building schools. An itemized listing of 140 completed construction projects is supplemented with pertinent facts and figures, including--(1) growth factors affecting school building needs, (2) resultant increases in the physical plant, staff and…

  20. Performance and experience of DRP-SSD-fifteen year experience

    International Nuclear Information System (INIS)

    Odedra, P.G.

    2002-01-01

    Radiotherapy plays a major role in the treatment of cancer and in developing countries like India, telecobalt units are widely used in rural radiotherapy centers. The measurement of output of these types of telecobalt unit using secondary standard dosimeter is an important duty of medical physicist. There are many sophisticated and costly imported dosimeters like farmer dosimeter and uni dose dosimeter available in the market for the calibration of teletherapy unit. But rural radiotherapy centres can't afford costly imported dosimeters and so output measurements are carried out using cheaper Indian made dosimeters like Control Dynamic Dosimeter (CD- High tech.) or DRP-SSD

  1. Fifteen years of Superfund at South Valley: Reengineering required

    International Nuclear Information System (INIS)

    Cormier, J.; Horak, F.

    1995-01-01

    It is no surprise to many of Superfund's practitioners that the law and its application are flawed. The South Valley Superfund Site in Albuquerque, New Mexico has not escaped Superfund's problems. The problems and issues arising out of the South Valley Superfund site have spurred the desire to seek a better way to administer and manage cleanup. This new method applies organizational and role changes that bring Superfund closer to an efficient business-like entity. This ''Reengineered'' Superfund strives for reorganization, contractor reduction, improved communication, reporting reduction, and teaming. In addition, modifications are made to the roles of regulators, potentially responsible parties (PRPs), and the public. Today the site encompasses roughly one square mile in area, includes six identified contaminant sources, and deals with solvent and petroleum by-product contamination

  2. Improving Learning and Reducing Costs: Fifteen Years of Course Description

    Science.gov (United States)

    Twigg, Carol A.

    2015-01-01

    Recognizing that tuition increases can no longer be used as a safety valve to avoid dealing with the underlying issues of why costs increase so much, campuses have begun the hard work of cost containment. After sharpening priorities, sometimes making tough choices in light of those priorities, campuses are still groping for ways to wrestle costs…

  3. Ten years after the introduction of Aldrovanda vesiculosa to the Czech Republic

    Czech Academy of Sciences Publication Activity Database

    Adamec, Lubomír

    2005-01-01

    Roč. 152, č. 2 (2005), s. 239-245 ISSN 1253-8078. [5th Conference of International Carnivorous Plant Society. Lyon, 17.06.2004-21.06.2004] Institutional research plan: CEZ:AV0Z6005908 Keywords : aquatic carnivorous plant, * Třeboňsko Area * dystrophic waters Subject RIV: EF - Botanics Impact factor: 0.224, year: 2005

  4. Evaluation of an Experimental Re-introduction of Sockeye Salmon into Skaha Lake; Year 1 of 3, 2000 Technical Report.

    Energy Technology Data Exchange (ETDEWEB)

    Hammell, Larry (University of Prince Edward Island, Atlantic Veterinary College, Charlottetown, PE, Canada); Machin, Deanna; Long, Karilyn (Okanagan National Fisheries Commission, Westbank, BC, Canada)

    2001-06-01

    Historical records indicate that sockeye salmon were once found in most of the lakes in the Okanagan River Basin. Currently, the only sockeye population within the Okanagan River Basin is found in Osoyoos Lake. Abundance of this stock has declined significantly in the last fifty years. The Okanagan Nation and tribes in the U.S. have proposed re-introducing the species into Okanagan Lake, which has a large rearing capacity. However, assessing the potential benefits and risks associated with a reintroduction of sockeye salmon into Okanagan Lake is difficult because of uncertainties about factors that determine production of Okanagan sockeye, and potential interactions with other species in Okanagan Lake. Associated with this proposal are the potential risks of re-introduction of sockeye salmon into Okanagan Lake. One of these is the effects of sockeye on the resident Okanagan Lake kokanee population, which has declined significantly in the past several years because of habitat loss due to human encroachment, competition with introduced mysid shrimp, and the reduction of biological productivity in the lake as municipalities have moved to more complete effluent treatment. Another concern is the possibility of the transmission of diseases that are currently not found in Okanagan and Skaha lakes from re-introduced sockeye to resident fish. An additional concern is the risk that exotic species (e.g. tench, largemouth bass), that have become established in southern Okanagan Lakes (principally as a result of purposeful introductions in the US Columbia/Okanagan river system), may be able to extend their range to Skaha and Okanagan Lakes, through fish ladders provided at the outlets of Vaseaux (McIntyre Dam) and Skaha Lakes (Okanagan Falls Dam), for natural upstream migration of sockeye. A transboundary multi-agency workshop was hosted in November of 1997 to discuss the potential risks and benefits of reintroducing sockeye salmon into Okanagan Lake. These discussions were

  5. Evaluation of the introduction of the OSCE to the fifth-year Geriatric Medicine Teaching Programme.

    Science.gov (United States)

    Vanlint, Andrew; Tam, Khai Loon; Yu, Solomon; Visvanathan, Renuka

    2016-12-01

    An Observed Structured Clinical Examination (OSCE) was integrated into the assessment for senior medical students undertaking a 4.5-week geriatric medicine teaching block at one campus. The feasibility and acceptability of an OSCE were examined. Students completed eight questions regarding the OSCE using a 6-point Likert scale and two additional questions, using free text, highlighting the strengths and potential areas for improvement. Changes were made every 6 months over a two-year period in response to student evaluation. Improvements included adjusting the format to conform with end-of-year examinations and introducing simulated patients. Following these improvements, students perceived improved structure and sequence to the assessments, improved opportunity for demonstration of skills and knowledge and that the assessment was fair. This preliminary research provides evidence that it is feasible to introduce OSCE as a form of assessment into a geriatric medicine teaching programme and student evaluation can be used to inform improvements. © 2016 AJA Inc.

  6. Fifty years on: Brown v. Board of Education and American psychology, 1954-2000: an introduction.

    Science.gov (United States)

    Pickren, Wade E

    2004-09-01

    Introduces the current issue of the American Psychologist, which examines the ramifications of the Brown vs. Board of Education decision and its sequelae over the last 50 years, with a special focus on the mixed role of psychological research and practice. Despite the great strides toward a more just society since May 17, 1954, inequities remain in schooling, in social relations, and in economic opportunity. How will history judge American psychology 50 years from now vis-a-vis the possibilities it helped create via Brown? The articles in this special issue suggest several important directions of research and action our field will need to take if the verdict of history is to be a positive one. ((c) 2004 APA, all rights reserved)

  7. Impact of meningococcal C conjugate vaccination four years after introduction of routine childhood immunization in Brazil.

    Science.gov (United States)

    Andrade, Ana Lucia; Minamisava, Ruth; Tomich, Lisia Moura; Lemos, Ana Paula; Gorla, Maria Cecilia; de Cunto Brandileone, Maria Cristina; Domingues, Carla Madga S; de Moraes, Camile; Policena, Gabriela; Bierrenbach, Ana Luiza

    2017-04-11

    Routine infant immunization with meningococcal C conjugate (MCC) vaccination started in Brazil in November 2010, scheduled at three and five months plus a booster at 12-15months of age. No catch-up was implemented. We assessed the impact of vaccination on meningococcal C disease (MenC) four years after vaccination start in the National Immunization Program. We performed an ecological quasi-experimental design from 2008 to 2014 using a deterministic linkage between the National Notification and the National Reference Laboratory databases for meningitis. We conducted an interrupted time-series analysis considering Brazil except for Salvador municipality, because an epidemic of serogroup C disease occurred in this city, which prompted a mass vaccination campaign with catch-up for adolescents in 2010. Observed MenC rates in the post-vaccination period were compared to expected rates calculated from the pre-vaccination years. Results for Salvador were presented as descriptive data. An additional time-series analysis was performed for the state of São Paulo. A total of 18,136 MenC cases were analyzed. The highest incidence rates were observed for infants aged Brazil, MenC rates were reduced by 67.2% (95%CI 43.0-91.4%) for infants Brazil in individuals aged Brazil. After four years of infants and toddlers vaccination start, MenC invasive disease reduced in the target population. This investigation provide a robust baseline to ascertain how much the upcoming catch-up dose in 12-13years of age will accelerate the decrease in MenC incidence rates among youths in Brazil. Copyright © 2017. Published by Elsevier Ltd.

  8. Dynamics of herbaceous vegetation during four years of experimental coppice introduction

    Czech Academy of Sciences Publication Activity Database

    Hédl, Radim; Šipoš, Jan; Chudomelová, Markéta; Utinek, D.

    2017-01-01

    Roč. 52, č. 1 (2017), s. 83-99 ISSN 1211-9520 R&D Projects: GA MŠk(CZ) EE2.3.20.0267 EU Projects: European Commission(XE) 278065 - LONGWOOD Institutional support: RVO:67985939 Keywords : biodiversity * ecological restoration * coppice-with-standards Subject RIV: EH - Ecology, Behaviour OBOR OECD: Plant sciences, botany Impact factor: 1.017, year: 2016

  9. Mont Terri rock laboratory, 20 years of research: introduction, site characteristics and overview of experiments

    Energy Technology Data Exchange (ETDEWEB)

    Bossart, P. [Swisstopo, Federal Office of Topography, Wabern (Switzerland); Bernier, F. [Federal Agency for Nuclear Control FANC, Brussels (Belgium); Birkholzer, J. [Lawrence Berkeley National Laboratory, Berkeley (United States); and others

    2017-04-15

    Geologic repositories for radioactive waste are designed as multi-barrier disposal systems that perform a number of functions including the long-term isolation and containment of waste from the human environment, and the attenuation of radionuclides released to the subsurface. The rock laboratory at Mont Terri (canton Jura, Switzerland) in the Opalinus Clay plays an important role in the development of such repositories. The experimental results gained in the last 20 years are used to study the possible evolution of a repository and investigate processes closely related to the safety functions of a repository hosted in a clay rock. At the same time, these experiments have increased our general knowledge of the complex behaviour of argillaceous formations in response to coupled hydrological, mechanical, thermal, chemical, and biological processes. After presenting the geological setting in and around the Mont Terri rock laboratory and an overview of the mineralogy and key properties of the Opalinus Clay, we give a brief overview of the key experiments that are described in more detail in the following research papers to this Special Issue of the Swiss Journal of Geosciences. These experiments aim to characterise the Opalinus Clay and estimate safety-relevant parameters, test procedures, and technologies for repository construction and waste emplacement. Other aspects covered are: bentonite buffer emplacement, high-pH concrete-clay interaction experiments, anaerobic steel corrosion with hydrogen formation, depletion of hydrogen by microbial activity, and finally, release of radionuclides into the bentonite buffer and the Opalinus Clay barrier. In the case of a spent fuel/high-level waste repository, the time considered in performance assessment for repository evolution is generally 1 million years, starting with a transient phase over the first 10,000 years and followed by an equilibrium phase. Experiments dealing with initial conditions, construction, and waste

  10. Introduction of organised mammography screening in Tyrol: results following first year of complete rollout

    Directory of Open Access Journals (Sweden)

    Knapp Rudolf

    2011-08-01

    Full Text Available Abstract Background In Tyrol, Austria, the existing system of spontaneous mammography screening was switched in 2007 to an organised program by smoothly changing the established framework. This process followed most EU recommendations for organised mammography screening with the following exceptions: women aged 40-49 are part of the target population, screening is offered annually to the age group 40-59, breast ultrasound is available as an additional diagnostic tool, and double reading has not yet been implemented. After a pilot phase the program was rolled out to all of Tyrol in June 2008. The aim of this study was to analyse the performance of the organised screening system by comparing quality indices and recommended levels given in the well-established EU guidelines. Methods Working from the results of the pilot phase, we extended the organised mammography system to all counties in Tyrol. All women living in Tyrol and covered by compulsory social insurance were invited for a mammography, in the age group 40-59 annually and in the age group 60-69 biennially. Screening mammography was offered mainly by radiologists in private practice, with further assessment performed at hospitals. Using the screening database, all well-established performance indicators were analysed and compared with accepted/desired levels as per the EU guidelines. Results From June 2008 to May 2009, 120,440 women were invited. Per 1000 mammograms, 14 women were recalled for further assessment, nine underwent biopsy and four cancer cases were detected. Of invasive breast cancer cases, 32.3% and 68.4% were ≤ 10 mm and ≤ 15 mm in size, respectively, and 79.2% were node-negative. The positive predictive value for further assessment and for biopsy was 25.9% and 39.9%, respectively. Estimated two-year participation rate was 57.0%. In total, 14 interval cancer cases were detected during one year of follow-up; this is 18.4% of the background incidence rate. Conclusions In

  11. Survival and Competitiveness of Bradyrhizobium japonicum Strains 20 Years after Introduction into Field Locations in Poland.

    Science.gov (United States)

    Narożna, Dorota; Pudełko, Krzysztof; Króliczak, Joanna; Golińska, Barbara; Sugawara, Masayuki; Mądrzak, Cezary J; Sadowsky, Michael J

    2015-08-15

    It was previously demonstrated that there are no indigenous strains of Bradyrhizobium japonicum forming nitrogen-fixing root nodule symbioses with soybean plants in arable field soils in Poland. However, bacteria currently classified within this species are present (together with Bradyrhizobium canariense) as indigenous populations of strains specific for nodulation of legumes in the Genisteae tribe. These rhizobia, infecting legumes such as lupins, are well established in Polish soils. The studies described here were based on soybean nodulation field experiments, established at the Poznań University of Life Sciences Experiment Station in Gorzyń, Poland, and initiated in the spring of 1994. Long-term research was then conducted in order to study the relation between B. japonicum USDA 110 and USDA 123, introduced together into the same location, where no soybean rhizobia were earlier detected, and nodulation and competitive success were followed over time. Here we report the extra-long-term saprophytic survival of B. japonicum strains nodulating soybeans that were introduced as inoculants 20 years earlier and where soybeans were not grown for the next 17 years. The strains remained viable and symbiotically competent, and molecular and immunochemical methods showed that the strains were undistinguishable from the original inoculum strains USDA 110 and USDA 123. We also show that the strains had balanced numbers and their mobility in soil was low. To our knowledge, this is the first report showing the extra-long-term persistence of soybean-nodulating strains introduced into Polish soils and the first analyzing the long-term competitive relations of USDA 110 and USDA 123 after the two strains, neither of which was native, were introduced into the environment almost 2 decades ago. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  12. [Jonathan Swift's asylum in Dublin--Ireland's introduction to institutional psychiatry 250 years ago].

    Science.gov (United States)

    Reuber, M

    1995-09-01

    250 years ago, the satirical writer and clergyman Jonathan Swift from Dublin (1667-1745) founded the first Irish lunatic asylum. Rejecting the theories put forward by the English philosopher Thomas Hobbes and the doctor Thomas Willis, he was influenced by the ideas of the Scottish doctor and the "enlightened" thinker John Locke. Swift's St. Patrick's Hospital did not, however, realise a new philosophical concept: architecture and therapeutic approach of the new institution were clearly modelled on the much older Hospital of St. Mary of Bethlehem ( = Bedlam). Despite its conservative conceptual basis, the first institution dedicated to the mentally ill and intellectually subnormal in Ireland became a starting point for the apparantly unstoppable expansion of the, at one time, most comprehensive asylum system in the world. After Swift's Hospital had been enlarged twice at the tax-payers' expense (1778, 1793), the administration decided to relieve the institution by erecting the Richmond Asylum (1810), the first public asylum in Ireland. When this establishment also became overcrowded, in 1817, legislation was passed which led to the establishment of the oldest system of public asylums in Europe.

  13. [Evaluation of dysphagia. Results after one year of incorporating videofluoroscopy into its study introduction].

    Science.gov (United States)

    García Romero, Ruth; Ros Arnal, Ignacio; Romea Montañés, María José; López Calahorra, José Antonio; Gutiérrez Alonso, Cristina; Izquierdo Hernández, Beatriz; Martín de Vicente, Carlos

    2017-11-09

    Dysphagia is very common in children with neurological disabilities. These patients usually suffer from respiratory and nutritional problems. The videofluoroscopic swallowing study (VFSS) is the most recommended test to evaluate dysphagia, as it shows the real situation during swallowing. To analyse the results obtained in our centre after one year of the implementation of VFSS, the clinical improvement after confirmation, and the prescription of an individualised treatment for the patients affected. VFSS performed in the previous were collected. The following variables were analysed: age, pathology, degree of neurological damage, oral and pharyngeal and/or oesophageal dysphagia and its severity, aspirations, prescribed treatment, and nutritional and respiratory improvement after diagnosis. A statistical analysis was performed using SPSS v21. A total of 61 VFSS were performed. Dysphagia was detected in more than 70%, being moderate-severe in 58%. Aspirations and/or penetrations were recorded in 59%, of which 50% were silent. Adapted diet was prescribed to 56%, and gastrostomy was performed on 13 (21%) patients. A statistical association was found between neurological disease and severity of dysphagia. The degree of motor impairment is related to the presence of aspirations. After VFSS evaluation and treatment adjustment, nutritional improvement was found in Z-score of weight (+0.3SD) and BMI (+0.4SD). There was respiratory improvement in 71% of patients with dysphagia being controlled in the Chest Diseases Department. After implementation of VFSS, a high percentage of patients were diagnosed and benefited from a correct diagnosis and treatment. VFSS is a fundamental diagnostic test that should be included in paediatric centres as a diagnostic method for children with suspected dysphagia. Copyright © 2017. Publicado por Elsevier España, S.L.U.

  14. Perspectives on transgenic, herbicide-resistant crops in the United States almost 20 years after introduction.

    Science.gov (United States)

    Duke, Stephen O

    2015-05-01

    Herbicide-resistant crops have had a profound impact on weed management. Most of the impact has been by glyphosate-resistant maize, cotton, soybean and canola. Significant economic savings, yield increases and more efficacious and simplified weed management have resulted in widespread adoption of the technology. Initially, glyphosate-resistant crops enabled significantly reduced tillage and reduced the environmental impact of weed management. Continuous use of glyphosate with glyphosate-resistant crops over broad areas facilitated the evolution of glyphosate-resistant weeds, which have resulted in increases in the use of tillage and other herbicides with glyphosate, reducing some of the initial environmental benefits of glyphosate-resistant crops. Transgenic crops with resistance to auxinic herbicides, as well as to herbicides that inhibit acetolactate synthase, acetyl-CoA carboxylase and hydroxyphenylpyruvate dioxygenase, stacked with glyphosate and/or glufosinate resistance, will become available in the next few years. These technologies will provide additional weed management options for farmers, but will not have all of the positive effects (reduced cost, simplified weed management, lowered environmental impact and reduced tillage) that glyphosate-resistant crops had initially. In the more distant future, other herbicide-resistant crops (including non-transgenic ones), herbicides with new modes of action and technologies that are currently in their infancy (e.g. bioherbicides, sprayable herbicidal RNAi and/or robotic weeding) may affect the role of transgenic, herbicide-resistant crops in weed management. Published 2014. This article is a U.S. Government work and is in the public domain in the USA. Published 2014. This article is a U.S. Government work and is in the public domain in the USA.

  15. Introduction of virtual patients onto a final year anesthesia course: Hong Kong experience

    Directory of Open Access Journals (Sweden)

    Joseph YC Leung

    2011-02-01

    Full Text Available Joseph YC Leung1, Lester AH Critchley1, Alex LK Yung2, Shekhar M Kumta21Department of Anaesthesia and Intensive Care, 2Department of Traumatology and Orthopaedics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong KongAbstract: e-Learning has revolutionized the way in which undergraduate medical education is delivered. One e-learning tool of note is the virtual patient (VP, a type of computer software that simulates real-life clinical scenarios, in which the learner emulates the role of health care provider to obtain the history, conduct examination, and make diagnoses and management decisions. VPs have been in use since 1993. Early designs were based on serial screen-cards of patient history, examination, investigations, diagnoses, treatment, and outcome, which the learner explored. With the development of web technology, VPs can now be accessed via the Internet and are more versatile, supporting different structural designs to suit a variety of learning objectives, and they can branch via different routes through a case. Using VPs has a number of advantages: 1 VPs improve access to learning material, 2 VPs help learners to acquire higher order cognitive skills like strategic thinking and decision making, 3 VPs provide a safe environment to practice, 4 VPs help to teach interdisciplinary care, and 5 VPs can be used instead of patients for examination. A number of well-known VP player systems are in use today: CASUS, CAMPUS, web-based Simulation of Patients, OpenLabyrinth, and vpSim. At the Chinese University of Hong Kong, we have also developed a web-based VP authoring and player system called Formative Assessment Case Studies (FACS, which is run by our Teaching and Learning Resources Centre. FACS has been integrated into Year-5 Anesthesia teaching since 2006. Three VP products have been developed: Anaesthesia FACS (six cases that teaches preoperative assessment, Acute Pain Management FACS, and an

  16. Survival in women with ovarian cancer before and after the introduction of adjuvant paclitaxel; a 25-year, single institution review.

    LENUS (Irish Health Repository)

    Shireen, R

    2012-02-01

    Adjuvant chemotherapy regime for ovarian cancer patients remains to be a contentious issue. The aim of this study was to compare the overall and progression-free survival of women with ovarian cancer before and after introduction of paclitaxel in our unit in 1992. A sample of 112 women who received adjuvant therapy following surgery for ovarian cancer was collected, 68 (61%) received platinum+alkylating agent before 1992 and later 44 (39%) received platinum+paclitaxel. Five-year survival was same in both treatment groups when there was no macroscopic disease after surgery (78% versus 70%) and when residual disease was <2 cm (50% versus 40%). Survival was greater in women with residual disease >2 cm in the platinum+paclitaxel group (50% versus 24%), (p = 0.04). However, progression-free survival was similar in both groups irrespective of stage or residual volume of disease. Therefore consideration to selective use of paclitaxel could reduce patient morbidity and costs significantly.

  17. Monovalent Rotavirus Vaccine Effectiveness and Impact on Rotavirus Hospitalizations in Zanzibar, Tanzania: Data From the First 3 Years After Introduction.

    Science.gov (United States)

    Abeid, Khamis Ali; Jani, Bhavin; Cortese, Margaret M; Kamugisha, Christopher; Mwenda, Jason M; Pandu, Aziza Salim; Msaada, Kazija Ali; Mohamed, Abdallah Said; Khamis, Asha Ussi; Parashar, Umesh D; Saleh, Abdulhamid A

    2017-01-15

    Low-income settings challenge the level of protection provided by live attenuated oral rotavirus vaccines. Rotarix (RV1) was introduced in the United Republic of Tanzania in early 2013, with 2 doses given at the World Health Organization-recommended schedule of ages 6 and 10 weeks, along with oral poliovirus vaccine. We performed active surveillance for rotavirus hospitalizations at the largest hospital in Zanzibar, Tanzania, from 2010 through 2015. Using a case-test-negative control design, we estimated the vaccine effectiveness (VE) of 2 RV1 doses in preventing rotavirus hospitalizations. Based on 204 rotavirus case patients and 601 test-negative controls aged 5-23 months, the VE of 2 RV1 doses against hospitalization for rotavirus diarrhea was 57% (95% confidence interval, 14%-78%). VE tended to increase against hospitalizations with higher severity, reaching 69% (95% confidence interval, 15%-88%) against the severity score for the top quarter of case patients. Compared with the prevaccine period, there were estimated reductions of 40%, 46%, and 69% in the number of rotavirus hospitalizations among infants in 2013, 2014, and 2015, respectively, and reductions of 36%, 26%, and 64%, respectively, among children aged <5 years. With data encompassing 3 years before and 3 years after vaccine introduction, our results indicate that successful delivery of RV1 on the current World Health Organization schedule can provide substantial health benefits in a resource-limited setting. Published by Oxford University Press for the Infectious Diseases Society of America 2016. This work is written by (a) US Government employee(s) and is in the public domain in the US

  18. Vigour and behaviour of fifteen citrus varieties against tristeza in the ...

    African Journals Online (AJOL)

    Fifteen varieties or combinations of citrus (lime, grapefruit, lemons, oranges, mandarin and hybrids) were characterized in the forest zone of Cameroon. Characterization was carried out based on the behaviour of these citrus varieties against citrus tristeza virus (CTV). Foliar and cortical symptoms were evaluated. Six years ...

  19. Fifteen: Combining Magic Squares and Tic-Tac-Toe

    Science.gov (United States)

    Yeo, Joseph B. W.

    2012-01-01

    Most students love to play games. Ernest (1986) believed that games could be used to teach mathematics effectively in four areas: motivation, concept development, reinforcement of skills, and practice of problem-solving strategies. Fifteen is an interesting and thought-provoking game that helps students learn mathematics at the same time. Playing…

  20. Methylene blue for vasoplegic syndrome treatment in heart surgery: fifteen years of questions, answers, doubts and certainties Azul de metileno no tratamento da síndrome vasoplégica em cirurgia cardíaca: quinze anos de perguntas, respostas, dúvidas e certezas

    Directory of Open Access Journals (Sweden)

    Paulo Roberto Barbosa Evora

    2009-09-01

    Full Text Available OBJECTIVE: There is strong evidence that methylene blue (MB, an inhibitor of guanylate cyclase, is an excellent therapeutic option for vasoplegic syndrome (VS treatment in heart surgery. The aim of this article is to review the MB's therapeutic function in the vasoplegic syndrome treatment. METHODS: Fifteen years of literature review. RESULTS: 1 Heparin and ACE inhibitors are risk factors; 2 In the recommended doses it is safe (the lethal dose is 40 mg/kg; 3 The use of MB does not cause endothelial dysfunction; 4 The MB effect appears in cases of nitric oxide (NO up-regulation; 5 MB is not a vasoconstrictor, by blocking of the GMPc system it releases the AMPc system, facilitating the norepinephrine vasoconstrictor effect; 6 The most used dosage is 2 mg/kg as IV bolus followed by the same continuous infusion because plasmatic concentrations strongly decays in the first 40 minutes; 7 There is a possible "window of opportunity" for the MB's effectiveness. CONCLUSIONS: Although there are no definitive multicentric studies, the MB used to treat heart surgery VS, at the present time, is the best, safest and cheapest option, being a Brazilian contribution for the heart surgeryOBJETIVO: Existem fortes evidências de que o azul de metileno (AM, um inibidor da guanilato ciclase, é uma excelente opção terapêutica para o tratamento da síndrome vasoplégica (SV em cirurgia cardíaca. O objetivo deste artigo é rever o papel terapêutico do AM no tratamento da SV. MÉTODOS: Revisão da literatura em período de 15 anos. RESULTADOS: 1 A heparina e inibidores da ECA são fatores de risco; 2 Nas doses preconizadas é droga segura (a dose letal é de 40 mg/kg; 3 O AM não causa disfunção endotelial; 4 O efeito do AM só aparece em caso de supra-regulação de óxido nítrico (NO; 5 O AM não é um vasoconstritor, pelo bloqueio do sistema GMPc ele "libera" o sistema AMPc, facilitando o efeito vasoconstritor da noradrenalina; 6 A dosagem mais utilizada é 2

  1. Introduction of an NT-proBNP assay to an acute admission unit--a 2-year audit.

    LENUS (Irish Health Repository)

    Murtagh, Gillian

    2012-02-01

    BACKGROUND: The differential diagnosis of dyspnoea is difficult due to the low predictive value of clinical and laboratory parameters. The elevated levels of NT-proBNP in congestive heart failure may improve diagnostic accuracy. We have evaluated the effect of the introduction of an NT-proBNP assay on hospital length of stay (LOS) and mortality. METHODS: There were 11,853 AMAU patient episodes in the 22 months study period (March 2005-Dec 2006). An NT-proBNP assay was requested in 657 (5.5%) of these. Comparison between categorical variables such as diagnosis, NT-proBNP testing, LOS, and in-hospital mortality was made using Chi-square tests. Literature review suggested that an NT-proBNP cut-off >or=5000 ng\\/L should predict acute in-patient mortality. Logistic regression analysis was used to examine the association between such an elevated NT-proBNP level and outcomes. RESULTS: Of the 396 patients with NT-proBNP <5000 ng\\/L, 8.1% died compared with 22.5% of the 178 patients dying with values >or=5000 ng\\/L (p<0.0001). An NT-proBNP >or=5000 ng\\/L was predictive of both LOS >or=9 days (odds ratios (OR) 1.54 (95% CI 1.06, 2.24: p=0.02) and LOS >or=14 days (OR=1.87 (95% CI 1.29, 2.71: p=0.0009). NT-proBNP requests increased over time, from 2.6% to 8.2% of all patients; the result fell in the diagnostic range for CHF in 60% of requests. CONCLUSION: The introduction of an NT-proBNP was reflected in an appropriate but rapidly increasing pattern of requests from clinicians. High NT-proBNP levels predicted in-hospital mortality and longer LOS in an acute medical population.

  2. Distribuição espacial de cobre, zinco e níquel em um Latossolo após quinze anos da aplicação de lodo de esgoto Soil spatial distribution of copper, zinc and nickel fifteen years after last application of sewage sludge

    Directory of Open Access Journals (Sweden)

    Carlos Antonio Centurion Maciel

    2012-01-01

    may be considered a rationale way to recycle this residue as source of plant nutrients and reduce its environmental impact. This work aimed to describe the spatial distribution of soil content of copper, zinc and nickel in a Typic Clayed Hapludox fifteen years after the last application of sewage sludge on it. From 1983 to 1987 the experimental plot was used in an assay with SS application at rates of 0, 20, 40, 60 and 80 t ha-1 and mineral fertilization with 0, 50, 100, and 150 kg ha-1 of N under maize cropping. After 1987 the area remained intact, covered with signal grass (Brachiaria decumbens Stapf vegetation, up to 2002 when soil and plant sampling were accomplished according to a spatial grid. Soil samples from 0-20 cm and at 20-40 cm depths, and aerial part of the grass were taken for chemical analysis. Soil and plant sampling were performed each 3 m in three parallel transects 15 m apart each other with an inclination of 45º in relation to the original baseline of the experimental area, completing fifty points of sampling. In order to assess the spatial variability of soil attributes and plant, geostatistics tools were used to determine the semivariograms and to draft the maps of isolines, as well as descriptive statistics for calculation of some parameters. Soil pH, soil organic matter and cation exchange capacity were not correlated with Cu, Zn and Ni for soil and plant. Both DTPA and Mehlich-3 were efficient to predict zinc availability. After 15 years of biosolid application Cu, Zn and Ni content at 0-20 cm depth, evaluated by DTPA and Mehlich-3, presented strong to moderate spatial dependency structure. Although, the degree of spatial dependency for Cu, Zn and Ni in plant tissues was different than the observed in the soil.

  3. Progress in the introduction of the rotavirus vaccine in Latin America and the Caribbean: four years of accumulated experience.

    Science.gov (United States)

    de Oliveira, Lucia Helena; Danovaro-Holliday, M Carolina; Sanwogou, N Jennifer; Ruiz-Matus, Cuauhtemoc; Tambini, Gina; Andrus, Jon Kim

    2011-01-01

    Two effective and safe rotavirus vaccines became available in 2006 and have been recommended for use in all countries by the World Health Organization. This article provides an update on the use of rotavirus vaccine in Latin American and Caribbean (LAC) countries. Data reported by LAC countries to the Pan American Health Organization (PAHO) were reviewed. As of May 2010, 14 LAC countries and 1 territory have introduced the rotavirus vaccine into their national expanded program on immunization (EPI). Reported coverage levels for rotavirus vaccine are lower than those for other EPI vaccines recommended at the same age. A total of 15 LAC countries are part of the PAHO's LAC rotavirus surveillance network; 12 of them are using the vaccine. LAC countries are conducting several studies on rotavirus vaccine effectiveness, cost-effectiveness, and monitoring safety. Also, LAC countries are generating lessons learned on the public health implications of introducing a new vaccine into the EPI. Nine countries and the Cayman Islands pay for the entire cost of the vaccine using government funds. All but 2 countries purchase their rotavirus vaccine through PAHO's Revolving Fund. Rotavirus vaccine introduction in LAC has been faster than for other new vaccines, but coverage levels need to increase to maximize the effect of the intervention. Rotavirus surveillance needs to expand and be strengthened to better assess the effect of vaccine use. LAC countries will continue to provide useful data to monitor rotavirus trends and vaccine effect.

  4. Introduction to imprecise probabilities

    CERN Document Server

    Augustin, Thomas; de Cooman, Gert; Troffaes, Matthias C M

    2014-01-01

    In recent years, the theory has become widely accepted and has been further developed, but a detailed introduction is needed in order to make the material available and accessible to a wide audience. This will be the first book providing such an introduction, covering core theory and recent developments which can be applied to many application areas. All authors of individual chapters are leading researchers on the specific topics, assuring high quality and up-to-date contents. An Introduction to Imprecise Probabilities provides a comprehensive introduction to imprecise probabilities, includin

  5. A Student-Led Introduction to Lesbian, Gay, Bisexual, and Transgender Health for First-Year Medical Students.

    Science.gov (United States)

    Grosz, Andrea M; Gutierrez, Daniel; Lui, Andrea A; Chang, Julia J; Cole-Kelly, Kathy; Ng, Henry

    2017-01-01

    Lesbian, gay, bisexual, and transgender (LGBT) individuals face significant health disparities. This is in part because many physicians are not sensitive to, and/or are underprepared to address, LGBT-specific concerns. To help meet this need, we, a group of second- and fourth-year medical students with faculty oversight, organized a session on LGBT health for first-year medical students. The three second-year and one fourth-year student authors designed a mandatory session for the 167 first-years at Case Western Reserve University School of Medicine in Cleveland, OH. The 2-hour session consisted of a student-delivered presentation, a patient panel, and a small-group session. Students' LGBT health knowledge and confidence in providing care were assessed anonymously before and after the session, and individuals' pre- and post-session assessments were paired using student-generated identifiers. A total of 73 complete, matched pre-/post-session assessments were received. Students' familiarity with LGBT terminology and demographics increased significantly after the session. Students' perceived preparedness and comfort in providing LGBT-specific care significantly improved in most areas as well. Students strongly praised the session, in particular the patient panel. A student-led educational session on LGBT health can effectively improve first-year medical students' LGBT knowledge and confidence to provide care.

  6. Changes in the epidemiology of hepatitis A outbreaks 13 years after the introduction of a mass vaccination program

    Science.gov (United States)

    Martínez, Ana; Broner, Sonia; Sala, M Rosa; Manzanares-Laya, Sandra; Godoy, Pere; Planas, Caritat; Minguell, Sofia; Torner, Nuria; Jané, Mireia; Domínguez, Angela; for the Study of the Immune Status in Health Care, the Working Group; Hepatitis A in Catalonia, for the Study of

    2014-01-01

    A hepatitis A+B vaccine vaccination program of 12-year-olds was introduced in Catalonia in 1998. The aim of this study was to investigate the evolution of hepatitis A outbreaks in Catalonia and estimate the preventable fraction of cases associated with outbreaks as a measure of the impact of the vaccination program. Hepatitis A outbreaks reported to the Health Department between 1991 and 2012 were analyzed. The incidence rates of outbreaks, outbreak-associated cases and hospitalizations were calculated. The preventable fraction (PF) and 95% confidence intervals (CI) were estimated for the whole study period (pre-vaccination and post-vaccination) and the post-vaccination period. One-hundred-eight (108) outbreaks (rate of 2.21 per 106 persons-year) were reported in the pre-vaccination period and 258 outbreaks (rate of 2.82 per 106 persons-year) in the post-vaccination period. The rate of cases associated with outbreaks was 1.52 per 105 persons-year in the pre-vaccination period and 1.28 per 105 persons-year in the post-vaccination period. Hospitalization rates were 0.08 and 0.75 per 106 persons-year, respectively. The number of person-to-person outbreaks whose index case was a school contact decreased in the post-vaccination period (aOR 2.72; 95%CI 1.35–5.48), but outbreaks whose index case was a man who has sex with men (MSM) or an immigrant increased. The PF of all outbreak-associated cases was 6.46% (95%CI 3.11–9.82) and the highest PF was in the 15–24 years age group (42.53%; 95%CI 29.30–55.75). In the 0–4 years age group, the PF was 18.35% (95%CI 9.59–27.11), suggesting a protective herd effect in unvaccinated subjects. Vaccination of immigrants traveling to endemic countries and MSM should be reinforced. PMID:25483535

  7. An Investigation into Student Perceptions towards Mathematics and Their Performance in First Year Chemistry: Introduction of Online Maths Skills Support

    Science.gov (United States)

    Johnston, Peter R.; Watters, Dianne J.; Brown, Christopher L.; Loughlin, Wendy A.

    2016-01-01

    An online Maths Skills Site was developed as an integrated support programme for first year Chemistry students, the content of which, was based on an analysis of their high-school mathematical backgrounds. This study examined the students' perceptions of Maths, their patterns of usage of the Maths Skills Site and whether there was a relationship…

  8. Using Quantum Mechanics to Facilitate the Introduction of a Broad Range of Chemical Concepts to First-Year Undergraduate Students

    Science.gov (United States)

    deSouza, Romualdo T.; Iyengar, Srinivasan S.

    2013-01-01

    A first-year undergraduate course that introduces students to chemistry through a conceptually detailed description of quantum mechanics is outlined. Quantization as arising from the confinement of a particle is presented and these ideas are used to introduce the reasons behind resonance, molecular orbital theory, degeneracy of electronic states,…

  9. Increase in best practice child car restraint use for children aged 2-5 years in low socioeconomic areas after introduction of mandatory child restraint laws.

    Science.gov (United States)

    Brown, Julie; Keay, Lisa; Hunter, Kate; Bilston, Lynne E; Simpson, Judy M; Ivers, Rebecca

    2013-06-01

    To examine changes in child car restraint practices in low socioeconomic areas following the introduction of mandatory child car restraint legislation in New South Wales (NSW), Australia. Data from two cross-sectional studies of child car restraint use at pre-schools, early childhood centres and primary schools before and after the introduction of legislating mandatory age-appropriate car restraint use for children up to the age of seven years was used in this analysis. All included observations were from local government areas with socioeconomic status in the lowest 30% of urban Sydney. Children aged 2-5 years were observed in their vehicles as they arrived at observation sites (107 pre-legislation, 360 post-legislation). Multilevel logistic regression was used to examine changes in observed age-appropriate and correct use of car restraints. Age-appropriate car restraint use was higher post-legislation than pre-legislation. After controlling for child's age, parental income, language spoken at home and adjusting for clustering, the odds of children being appropriately restrained post-legislation were 2.3 times higher than in the pre-legislation sample, and the odds of them being correctly restrained were 1.6 times greater. Results indicate an improvement in car restraint practices among children aged 2-5 in low socioeconomic areas after introduction of child restraint laws. Implications : Despite improvements observed with enhanced legislation, further efforts are required to increase optimal child car restraint use. © 2013 The Authors. ANZJPH © 2013 Public Health Association of Australia.

  10. Evaluation of an Experimental Re-introduction of Sockeye Salmon into Skaha Lake; Year 2 of 3, 2001 Technical Report.

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, Christopher (Colville Confederated Tribes, Omak Community Center, Omak, WA); Machin, Deanna; Wright, Howie (Okanagan National Fisheries Commission, Westbank, BC, Canada)

    2002-04-01

    This report summarizes the findings from YEAR 2 of a three-year disease risk assessment. The Okanagan Nation Fisheries Commission (ONFC) and the Colville Confederated Tribes (CCT) are investigating the risks involved in re-introducing sockeye salmon into Skaha Lake, part of their historical range (Ernst and Vedan 2000). The disease risk assessment compares the disease and infection status of fish above and below McIntyre Dam (the present limit of sockeye migration). The disease agents identified that are of a particular concern are: infectious pancreatic necrosis virus (IPNV), infectious haematopoietic necrosis virus type 2 (IHNV type2), erythrocytic inclusion body syndrome virus (EIBSV), the whirling disease agent (Myxobolus cerebralis), and the ceratomyxosis agent (Ceratomyxa shasta).

  11. Geology of Libya Montes and the Interbasin Plains of Northern Tyrrhena Terra, Mars: Project Introduction and First Year Work Plan

    Science.gov (United States)

    Skiner, J. A., Jr.; Rogers, A. D.; Seelos, K. D.

    2009-01-01

    The highland-lowland boundary (HLB) of Mars is interpreted to be a complex tectonic and erosional transition that may hold evidence for past geologic processes and environments. The HLB-abutting margin of the Libya Montes and the interbasin plains of northern Tyrrhena Terra display an exceptional view of the earliest to middle history of Mars that has yet to be fully characterized. This region contains some of the oldest exposed materials on the Martian surface as well as aqueous mineral signatures that may be potential chemical artifacts of early highland formational processes. However, a full understanding of the regions geologic and stratigraphic evolution is remarkably lacking. Some outstanding questions regarding the geologic evolution of Libya Montes and northern Tyrrhena Terra in-clude: Does combining geomorphology and composition advance our understanding of the region s evolution? Can highland materials be subdivided into stratigraphically discrete rock and sediment sequences? What do major physiographic transitions imply about the balanced tectonism, climate change, and erosion? Where is the erosional origin and what is the post-depositional history of channel and plains units? When and in what types of environments did aqueous mineral signatures arise? This abstract introduces the geologic setting, science rationale, and first year work plan of a recently-funded 4-year geologic mapping proposal (project year = calendar year). The objective is to delineate the geologic evolution of Libya Montes and northern Tyrrhena Terra at 1:1M scale using both classical geomorphological and compositional mapping techniques. The funded quadrangles are MTMs 00282, -05282, -10282, 00277, -05277, and -10277.

  12. Age at first introduction of cow milk products and other food products in relation to infant atopic manifestations in the first 2 years of life: the KOALA Birth Cohort Study

    NARCIS (Netherlands)

    Snijders, Bianca E. P.; Thijs, Carel; van Ree, Ronald; van den Brandt, Piet A.

    2008-01-01

    OBJECTIVES: Scientific evidence is scarce about timing of solid-food introduction and its association with the development of atopy. We aimed to evaluate any associations between the introduction of cow milk products/other solid food products and infant atopic manifestations in the second year of

  13. Invasive pneumococcal disease among children younger than 5 years of age before and after introduction of pneumococcal conjugate vaccine in Casablanca, Morocco.

    Science.gov (United States)

    Diawara, Idrissa; Zerouali, Khalid; Katfy, Khalid; Zaki, Bahija; Belabbes, Houria; Najib, Jillali; Elmdaghri, Naima

    2015-11-01

    The purpose of this study was to compare the incidence rate of invasive pneumococcal disease, the rates of antibiotic resistance and serotype distribution among children ≤5 years old before and after PCVs introduction in Casablanca, Morocco. This study was conducted at the Ibn Rochd University Hospital Centre of Casablanca during two periods encompassing pre-and post-implementation of PCVs, respectively from January 2007 to October 2010 and from January 2011 to December 2014. All the non-duplicate invasive S. pneumoniae isolates recovered during the study periods were included. There were 136 cases of IPD, 91 before and 45 after PCVs introduction. The greatest decrease in incidence rate of IPD occurred in children ≤ 2 years of age declining from 34.6 to 13.5 per 100,000 populations (p<0.0001) before and after vaccination, respectively. The incidence rate of PCV-7, PCV-10 non-PCV-7 and PCV-13 non-PCV-10 serotypes decrease significantly from 18.0 to 4.6, from 5.7 to 1.3 and from 5.7 to 0.8/100,000 population (p<0.001) in the same age, respectively. Shifts in the distribution of IPD serotypes and reductions in the incidence rate of disease suggest an effective reduction of the burden of IPD in children, but continued high quality surveillance is critical to assess the changes in serotype distributions. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  14. Evaluation of Haemophilus influenzae type b carrier status among children 10 years after the introduction of Hib vaccine in Brazil

    OpenAIRE

    Zanella, Rosemeire Cobo; Brandileone, Maria Cristina de Cunto; Andrade, Ana L?cia; Ogassavara, Cinthya Terumi; Fi?rio, Cleiton Eduardo; Brand?o, Angela Pires; Almeida, Samanta Cristine Grassi; Lemos, Ana Paula Silva; Gorla, Maria Cec?lia; Carvalhanas, Telma Regina; Sato, Helena; Liphaus, Bernadete; Nerger, Maria L?gia; Conde, Monica; Ribeiro, Ana Freitas

    2015-01-01

    The aim of the present study was to assess the prevalence of Haemophilus influenzae type b (Hib) nasopharyngeal (NP) colonisation among healthy children where Hib vaccination using a 3p+0 dosing schedule has been routinely administered for 10 years with sustained coverage (> 90%). NP swabs were collected from 2,558 children who had received the Hib vaccine, of whom 1,379 were 12-< 24 months (m) old and 1,179 were 48-< 60 m old. Hi strains were identified by molecular methods. Hi carriage prev...

  15. [Introduction of team-based learning to the pharmacy experiential practice course for first-year pharmacy students].

    Science.gov (United States)

    Norose, Takahiko; Ito, Mika; Endo, Kikutaro; Fujimoto, Tetsuya; Moriya, Hiroyuki; Murakami, Miho

    2014-01-01

    In recent years, the number of high school graduates has decreased, whereas the number of new pharmacy schools has increased substantially. Therefore, pharmacy schools these days accommodate students from diverse backgrounds in terms of basic knowledge, study skills, and/or their motivation to be pharmacists. To address this issue, we developed a mandatory 10-day course named "Pharmacy experiential practice" for the first-year students. The program trains students in basic pharmacy calculation skills and communication skills, and provides an insight into how these skills can be applied in actual pharmacy practice. The program includes 5 themes, namely, "Compounds", "Solutions", "Infusions", "Nutrition" and "Communication". Each theme, except "Communication", was conducted for 2 days 3 hour calculation practice in class and 3 hour pharmacy experiential practice each day. In the calculation class, we introduced team-based learning, which enhanced the students for interactive learning in the classes. In the pharmacy experiential practices, the students were trained not only to apply their calculation skills to pharmacy practice in each theme, but also to understand the importance of basic science knowledge in strengthening the foundations for their calculation skills. Course evaluation showed that students experienced the effectiveness of interactive study and that they realized the importance of pharmacy practice and the basic sciences that they had learnt. Some students commented that their motivation to become pharmacists increased after this course.

  16. Brain Embolism Secondary to Cardiac Myxoma in Fifteen Chinese Patients

    Science.gov (United States)

    Long, Youming; Gao, Cong

    2014-01-01

    Background. Heart myxoma-related embolisms commonly involve the central nervous system, but data are lacking in Chinese patients. Methods. 27 patients diagnosed with myxoma were reviewed retrospectively. Results. Among 27 patients, fourteen (51.9%) patients were women. Fifteen (55.6%) patients had brain embolisms. Rarely, patients were misdiagnosed with central nervous system vasculitis (n = 2), moyamoya disease (n = 1), and neuromyelitis optica (n = 1). We found positive associations between mRS (>3) and female gender (r = 0.873, P 10 × 109/L (r = 0.722, P = 0.002), tumour size (r = 0.866, P 0.05). Conclusions. Neurologic manifestations in Chinese patients with cardiac myxoma-related stroke were complicated and multifarious. Female gender, infection, other severe complications, low SBP, tumour size, bilateral brain lesions, TACI, and high WBC counts could be associated with a poor prognosis. PMID:24737987

  17. Brain Embolism Secondary to Cardiac Myxoma in Fifteen Chinese Patients

    Directory of Open Access Journals (Sweden)

    Youming Long

    2014-01-01

    Full Text Available Background. Heart myxoma-related embolisms commonly involve the central nervous system, but data are lacking in Chinese patients. Methods. 27 patients diagnosed with myxoma were reviewed retrospectively. Results. Among 27 patients, fourteen (51.9% patients were women. Fifteen (55.6% patients had brain embolisms. Rarely, patients were misdiagnosed with central nervous system vasculitis (n = 2, moyamoya disease (n = 1, and neuromyelitis optica (n = 1. We found positive associations between mRS (>3 and female gender (r = 0.873, P10 × 109/L (r = 0.722, P = 0.002, tumour size (r = 0.866, P0.05. Conclusions. Neurologic manifestations in Chinese patients with cardiac myxoma-related stroke were complicated and multifarious. Female gender, infection, other severe complications, low SBP, tumour size, bilateral brain lesions, TACI, and high WBC counts could be associated with a poor prognosis.

  18. Clinical burden of pneumonia, meningitis and septicemia in Norway 2 years after 7-valent pneumococcal conjugate vaccine introduction.

    Science.gov (United States)

    Munson, Samantha; Raluy-Callado, Mireia; Lambrelli, Dimitra; Wasiak, Radek; Eriksson, Daniel; Gray, Sharon

    2015-08-01

    This population-based, retrospective study quantified the rates of all-cause and pneumococcal pneumonia, meningitis and septicemia in Norway from 2008 to 2009 and determined the proportions of cases caused by pneumococcal vaccine serotypes. Data on patients with all-cause and pneumococcal pneumonia, meningitis and septicemia were obtained from the Norwegian Patient Registry, which collects hospitalization data from all Norwegian public hospitals based on International Classification of Diseases codes. Norwegian Patient Registry case records linked to the Norwegian Surveillance System for Communicable Diseases provided serotype data for invasive pneumococcal disease in patients with microbiological cultures. In 2008 and 2009, hospitalization rates were relatively stable for all-cause pneumonia (5.28 and 5.35, respectively, per 1000), meningitis (10.70 and 9.67, respectively, per 100,000), and septicemia (from 171.81 to 161.46 per 100,000). In contrast, rates decreased for International Classification of Diseases-10 diagnosed pneumococcal pneumonia (from 13.66 to 10.52 per 100,000), although these cases may be under-reported because of inclusion in all-cause pneumonia. Rates also decreased in diagnosed pneumococcal meningitis (from 1.60 to 1.19 per 100,000) and diagnosed pneumococcal septicemia (from 9.08 to 7.94 per 100,000). Diagnosed pneumococcal disease rates were highest in younger children and older adults, peaking at ⩾ 60 years old. Pneumococcal pneumonia, meningitis and septicemia caused by serotypes included in the 7-valent pneumococcal conjugate vaccine decreased substantially during the study period, with corresponding serotype replacement by non-7-valent pneumococcal conjugate vaccine serotypes. From 2008 to 2009, International Classification of Diseases-10 diagnosed pneumococcal pneumonia, meningitis and septicemia decreased in most age groups but remained greatest among subjects aged 0-1 and ⩾ 60 years. © 2015 the Nordic Societies of Public Health.

  19. The jubilee of medical informatics in bosnia and herzegovina - 20 years anniversary.

    Science.gov (United States)

    Masic, Izet

    2009-01-01

    NONE DECLARED LAST TWO YEARS, THE HEALTH INFORMATICS PROFESSION CELEBRATED FIVE JUBILEES IN BOSNIA AND HERZEGOVINA: thirty years from the introduction of the first automatic manipulation of data, twenty years from the establishment of Society for Medical Informatics BiH, fifteen years from the establishment of the Scientific and Professional Journal of the Society for Medical Informatics of Bosnia and Herzegovina "Acta Informatica Medica", fifteen years on from the establishment of the first Cathedra for Medical Informatics on Biomedical Faculties in Bosnia and Herzegovina and five years on from the introduction of the method of "Distance learning" in medical curriculum. The author of this article are eager to mark the importance of the above mentioned Anniversaries in the development of Health informatics in Bosnia and Herzegovina and have attempted, very briefly, to present the most significant events and persons with essential roles throughout this period.

  20. Chytridiomycosis and seasonal mortality of tropical stream-associated frogs 15 years after introduction of Batrachochytrium dendrobatidis.

    Science.gov (United States)

    Phillott, Andrea D; Grogan, Laura F; Cashins, Scott D; McDonald, Keith R; Berger, Lee; Skerratt, Lee F

    2013-10-01

    Assessing the effects of diseases on wildlife populations can be difficult in the absence of observed mortalities, but it is crucial for threat assessment and conservation. We performed an intensive capture-mark-recapture study across seasons and years to investigate the effect of chytridiomycosis on demographics in 2 populations of the threatened common mist frog (Litoria rheocola) in the lowland wet tropics of Queensland, Australia. Infection prevalence was the best predictor for apparent survival probability in adult males and varied widely with season (0-65%). Infection prevalence was highest in winter months when monthly survival probabilities were low (approximately 70%). Populations at both sites exhibited very low annual survival probabilities (12-15%) but high recruitment (71-91%), which resulted in population growth rates that fluctuated seasonally. Our results suggest that even in the absence of observed mortalities and continued declines, and despite host-pathogen co-existence for multiple host generations over almost 2 decades, chytridiomycosis continues to have substantial seasonally fluctuating population-level effects on amphibian survival, which necessitates increased recruitment for population persistence. Similarly infected populations may thus be under continued threat from chytridiomycosis which may render them vulnerable to other threatening processes, particularly those affecting recruitment success. © 2013 Society for Conservation Biology.

  1. Protein quality evaluation twenty years after the introduction of the protein digestibility corrected amino acid score method.

    Science.gov (United States)

    Boye, Joyce; Wijesinha-Bettoni, Ramani; Burlingame, Barbara

    2012-08-01

    In 1989 the Joint FAO/WHO Expert Consultation on Protein Quality Evaluation recommended the use of the Protein Digestibility Corrected Amino Acid Score (PDCAAS) method for evaluating protein quality. In calculating PDCAAS, the limiting amino acid score (i.e., ratio of first limiting amino acid in a gram of target food to that in a reference protein or requirement) is multiplied by protein digestibility. The PDCAAS method has now been in use for 20 years. Research emerging during this time has provided useful data on various aspects of protein quality evaluation that has made a review of the current methods used in assessing protein quality necessary. This paper provides an overview of the use of the PDCAAS method as compared to other methods and addresses some of the key challenges that remain in regards to protein quality evaluation. Furthermore, specific factors influencing protein quality including the effects of processing conditions and preparation methods are presented. Protein quality evaluation methods and recommended protein intakes currently used in different countries vis-à-vis the WHO/FAO/UNU standards are further provided. As foods are frequently consumed in complement with other foods, the significance of the PDCAAS of single protein sources may not be evident, thus, protein quality of some key food groups and challenges surrounding the calculation of the amino acid score for dietary protein mixtures are further discussed. As results from new research emerge, recommendations may need to be updated or revised to maintain relevance of methods used in calculating protein quality.

  2. Revisiting reproduction and population structure and dynamics of Procambarus clarkii eight years after its introduction into Lake Trasimeno (Central Italy

    Directory of Open Access Journals (Sweden)

    Dörr A.J.M.

    2013-06-01

    Full Text Available Understanding population dynamics and regulation is fundamental for predicting establishment and spread of invasive alien species. In addition, the population biology of invasive alien species offers an opportunity to study basic ecological processes. In this context, we investigated reproductive and growth plasticity in the invasive crayfish Procambarus clarkii in Lake Trasimeno (central Italy. In total, 3153 crayfish were collected monthly from June 2007 to July 2009. The molt status was assessed by evaluating the exoskeleton hardness. To assess the reproductive cycle, the gonado-somatic and wet hepato-somatic indices were calculated for females. The reproductive status of males was appraised as well. We estimated growth and longevity using the von Bertalanffy growth function, and calculated the total, natural and fishing mortality indices. We then compared our present data with those obtained from the same population eight years before. Our results indicate some changes in population dynamics and in both molting and reproductive periods since the initial invasion of the shallow lake investigated. Long-term differences in the life history of the Trasimeno population may be the result of selective pressures different from those of the native range, but may also result from colonization events and human interference caused by professional fishing activities.

  3. Plasmodium falciparum infection in febrile Congolese children: prevalence of clinical malaria 10 years after introduction of artemisinin-combination therapies.

    Science.gov (United States)

    Etoka-Beka, Mandingha Kosso; Ntoumi, Francine; Kombo, Michael; Deibert, Julia; Poulain, Pierre; Vouvoungui, Christevy; Kobawila, Simon Charles; Koukouikila-Koussounda, Felix

    2016-12-01

    To investigate the proportion of malaria infection in febrile children consulting a paediatric hospital in Brazzaville, to determine the prevalence of submicroscopic malaria infection, to characterise Plasmodium falciparum infection and compare the prevalence of uncomplicated P. falciparum malaria according to haemoglobin profiles. Blood samples were collected from children aged <10 years with an axillary temperature ≥37.5 °C consulting the paediatric ward of Marien Ngouabi Hospital in Brazzaville. Parasite density was determined and all samples were screened for P. falciparum by nested polymerase chain reaction (PCR) using the P. falciparum msp-2 marker to detect submicroscopic infections and characterise P. falciparum infection. Sickle cell trait was screened by PCR. A total of 229 children with fever were recruited, of whom 10% were diagnosed with uncomplicated malaria and 21% with submicroscopic infection. The mean parasite density in children with uncomplicated malaria was 42 824 parasites/μl of blood. The multiplicity of infection (MOI) was 1.59 in children with uncomplicated malaria and 1.69 in children with submicroscopic infection. The mean haemoglobin level was 10.1 ± 1.7 for children with uncomplicated malaria and 12.0 ± 8.6 for children with submicroscopic infection. About 13% of the children harboured the sickle cell trait (HbAS); the rest had normal haemoglobin (HbAA). No difference in prevalence of uncomplicated malaria and submicroscopic infection, parasite density, haemoglobin level, MOI and P. falciparum genetic diversity was observed according to haemoglobin type. The low prevalence of uncomplicated malaria in febrile Congolese children indicates the necessity to investigate carefully other causes of fever. © 2016 John Wiley & Sons Ltd.

  4. Changes in invasive pneumococcal disease serotypes in a regional area of Australia following three years of 7vPCV introduction

    Directory of Open Access Journals (Sweden)

    Fakhrul Islam

    2012-06-01

    Full Text Available Background: Invasive pneumococcal disease (IPD is a serious bacterial disease. Vaccination can prevent disease for many of the current serotypes. The aim of this investigation was to describe the notification rates of IPD in a regional area of Australia, explore changes in rates since the introduction of the population vaccine programmes in 2005 and to describe changes in the distribution of serotypes in relation to the available vaccines after three years.Methods: Annualized IPD notification rates were calculated for residents of a regional area in northern New South Wales. Rates were analysed according to serotypes covered by available vaccines. Changes in serotypes were compared for the periods 2002–2004 and 2008–2010.Results: The annualized notification rate of IPD in all ages for the period 2002–2004 was 13.7 per 100 000 population and 8.3 per 100 000 population for the period 2008–2010 (rate ratio [RR], 0.61, confidence interval [CI]: 0.51–0.72. The largest decline was observed in 7-valent pneumococcal conjugate vaccine (7vPCV types across all age groups (RR, 0.17, CI: 0.12–0.24 and in the zero to four year age group (RR, 0.03, CI: 0.01–0.11. The six serotypes included in the new 13-valent pneumococcal conjugate vaccine, but not in the 7vPCV, accounted for 40.6% of IPD cases in the zero to four year age group during the period of 2008–2010.Discussion: The introduction of 7vPCV significantly reduced the overall notification rate of IPD caused by the serotypes contained in this vaccine. This decline in IPD rates in children can be directly attributed to the use of 7vPCV, and in adults it is most likely an indirect effect of the 7vPCV programme in children.

  5. MEASURING THE IMPACT OF CHILD MARRIAGE ON TOTAL FERTILITY: A STUDY FOR FIFTEEN COUNTRIES.

    Science.gov (United States)

    Onagoruwa, Adenike; Wodon, Quentin

    2017-11-20

    Child marriage has significant negative impacts, not only for girls, but also for a range of development outcomes. This study aimed to assess, in a more detailed way than done so far, the magnitude of the relationship between child marriage and total fertility in multiple countries representing diverse settings. Data from the most recent Demographic and Health Surveys in the fifteen countries of interest were used. Analysis was restricted to a subsample of women aged 35-49 years in order to capture completed fertility. Poisson regression was conducted to estimate the impact of each additional year of early marriage on the total number of births women have, controlling for selected sociodemographic characteristics. Counterfactual analyses were carried out to estimate the reduction in the number of children that women would have over their lifetime in the absence of child marriage. Controlling for socioeconomic and other characteristics, girls who marry as children have more children over their lifetime than women marrying after the age of 18. Nationally, across fifteen countries, the reduction in total fertility from ending child marriage ranges from 0.24 to 1.06 children per woman. The simulated change in total fertility that would result from ending child marriage tends to be higher in countries that have a higher incidence of child marriage.

  6. Orientalism: thirty years on. Introduction

    Directory of Open Access Journals (Sweden)

    Carles Prado-Fonts

    2008-05-01

    Full Text Available This dossier contains a series of articles inspired by Edward Said's concept of Orientalism. Together, the articles in the dossier show the importance of Said's contribution and defend the need to continue working to make it even more important and valid, both in the academic context and in terms of the social diffusion it deserves. With a common thematic thread -the perception of the other (Orient from our perspective (Occident- these articles shun the conception of East Asia as an independent "discipline" and treat it, on the contrary, as an object of study that must be tackled with methodological rigour from specific disciplines: history, thought, anthropology and literature. This should facilitate, on one hand, the possibility of putting forward arguments and observations that enrich already existing debates in each discipline by shedding new light on them and, on the other, social diffusion of these ideas on East Asia beyond limited circles.

  7. Timing of solid food introduction in relation to eczema, asthma, allergic rhinitis, and food and inhalant sensitization at the age of 6 years: results from the prospective birth cohort study LISA.

    Science.gov (United States)

    Zutavern, Anne; Brockow, Inken; Schaaf, Beate; von Berg, Andrea; Diez, Ulrike; Borte, Michael; Kraemer, Ursula; Herbarth, Olf; Behrendt, Heidrun; Wichmann, H-Erich; Heinrich, Joachim

    2008-01-01

    Current prophylactic feeding guidelines recommend a delayed introduction of solids for the prevention of atopic diseases. This study investigates whether a delayed introduction of solids (past 4 or 6 months) is protective against the development of eczema, asthma, allergic rhinitis, and food or inhalant sensitization at the age of 6 years. Data from 2073 children in the ongoing LISA birth cohort study were analyzed at 6 years of age. Multivariate logistic regression analyses were performed for all children and for children without skin or allergic symptoms within the first 6 months of life to take into account reverse causality. A delayed introduction of solids (past 4 or 6 months) was not associated with decreased odds for asthma, allergic rhinitis, or sensitization against food or inhalant allergens at 6 years of age. On the contrary, food sensitization was more frequent in children who were introduced to solids later. The relationship between the timing of solid food introduction and eczema was not clear. There was no protective effect of a late introduction of solids or a less diverse diet within the first 4 months of life. However, in children without early skin or allergic symptoms were considered, eczema was significantly more frequent in children who received a more diverse diet within the first 4 months. This study found no evidence supporting a delayed introduction of solids beyond 4 or 6 months for the prevention of asthma, allergic rhinitis, and food or inhalant sensitization at the age of 6 years. For eczema, the results were conflicting, and a protective effect of a delayed introduction of solids cannot be excluded. Positive associations between late introduction of solids and food sensitization have to be interpreted with caution. A true protective effect of a delayed introduction of solids on food sensitization seems unlikely.

  8. Presentation (Introduction)

    Science.gov (United States)

    Authier, Jacqueline; Meunier, Andre

    1977-01-01

    An introduction to this issue of "Langue Francaise," which is devoted to a study of the crisis in grammar instruction in French where French is the native language. The issue deals with grammar exercises from linguistic, psycholinguistic and pedagogical points of view. (Text is in French.) (AMH)

  9. 77 Introduction

    African Journals Online (AJOL)

    `123456789jkl''''#

    residential areas in the town.The need to consider users' household-size, among other relevant socio-cultural parameters in the design and development of qualitative housing in Nigeria is emphasized. Keywords: Housing quality; household-size; socio-cultural parameters; Osogbo; Nigeria. Introduction t has been asserted ...

  10. Editorial introduction

    DEFF Research Database (Denmark)

    Hviid, Karen Pernille

    2008-01-01

    This editorial introduction frames the special issue by highlighting its choices: examining transitions in the educational process, so as to highlight common features of many educational phenomena, often considered separately; and conceptualise transitions as time-embedded processes. Such theoret...... are thus presented through its specific methodological choices. Finally, two transversal characteristics of transitions are highlighted: the person-and-environment mutual responsiveness, and their inherent playfulness; some consequenses for education are suggested.......This editorial introduction frames the special issue by highlighting its choices: examining transitions in the educational process, so as to highlight common features of many educational phenomena, often considered separately; and conceptualise transitions as time-embedded processes....... Such theoretical choices raise methodological questions. among which, that of preserving the dynamics of education. Three main methodological options for doing so are considered: time construction (verbal or graphic); real-time data gathering; and focus on the individual-social articulation. Each of the papers...

  11. Fusion: introduction

    International Nuclear Information System (INIS)

    Decreton, M.

    2006-01-01

    The article gives an overview and introduction to the activities of SCK-CEN's research programme on fusion. The decision to construct the ITER international nuclear fusion experiment in Cadarache is highlighted. A summary of the Belgian contributions to fusion research is given with particular emphasis on studies of radiation effects on diagnostics systems, radiation effects on remote handling sensing systems, fusion waste management and socio-economic studies

  12. Population Impact and Effectiveness of Monovalent Rotavirus Vaccination in Urban Malawian Children 3 Years After Vaccine Introduction: Ecological and Case-Control Analyses.

    Science.gov (United States)

    Bar-Zeev, Naor; Jere, Khuzwayo C; Bennett, Aisleen; Pollock, Louisa; Tate, Jacqueline E; Nakagomi, Osamu; Iturriza-Gomara, Miren; Costello, Anthony; Mwansambo, Charles; Parashar, Umesh D; Heyderman, Robert S; French, Neil; Cunliffe, Nigel A

    2016-05-01

    Rotavirus vaccines have been introduced in many low-income African countries including Malawi in 2012. Despite early evidence of vaccine impact, determining persistence of protection beyond infancy, the utility of the vaccine against specific rotavirus genotypes, and effectiveness in vulnerable subgroups is important. We compared rotavirus prevalence in diarrheal stool and hospitalization incidence before and following rotavirus vaccine introduction in Malawi. Using case-control analysis, we derived vaccine effectiveness (VE) in the second year of life and for human immunodeficiency virus (HIV)-exposed and stunted children. Rotavirus prevalence declined concurrent with increasing vaccine coverage, and in 2015 was 24% compared with prevaccine mean baseline in 1997-2011 of 32%. Since vaccine introduction, population rotavirus hospitalization incidence declined in infants by 54.2% (95% confidence interval [CI], 32.8-68.8), but did not fall in older children. Comparing 241 rotavirus cases with 692 test-negative controls, VE was 70.6% (95% CI, 33.6%-87.0%) and 31.7% (95% CI, -140.6% to 80.6%) in the first and second year of life, respectively, whereas mean age of rotavirus cases increased from 9.3 to 11.8 months. Despite higher VE against G1P[8] than against other genotypes, no resurgence of nonvaccine genotypes has occurred. VE did not differ significantly by nutritional status (78.1% [95% CI, 5.6%-94.9%] in 257 well-nourished and 27.8% [95% CI, -99.5% to 73.9%] in 205 stunted children;P= .12), or by HIV exposure (60.5% [95% CI, 13.3%-82.0%] in 745 HIV-unexposed and 42.2% [95% CI, -106.9% to 83.8%] in 174 exposed children;P= .91). Rotavirus vaccination in Malawi has resulted in reductions in disease burden in infants <12 months, but not in older children. Despite differences in genotype-specific VE, no genotype has emerged to suggest vaccine escape. VE was not demonstrably affected by HIV exposure or stunting. © The Author 2016. Published by Oxford University Press

  13. The impact of generic substitution on the activities of pharmaceutical companies - a survey from the companies' perspective one year and five years after the introduction of generic substitution in finland.

    Science.gov (United States)

    Timonen, Johanna; Bengtström, Marina; Karttunen, Pekka; Ahonen, Riitta

    2010-10-22

    Mandatory generic substitution (GS) was introduced in Finland on 1 April 2003. The aim of this study was to explore and compare the impacts of GS on the activities of pharmaceutical companies representing mainly original or generic pharmaceutical products in Finland. The self-reported impact of GS from pharmaceutical companies' perspective was explored with a focus on the number of employees, the range of sales packages on the market, the marketing activities, the research and development of new pharmaceutical products and storage of pharmaceuticals. A cross-sectional postal survey was conducted among pharmaceutical companies with an office in Finland and substitutable medicines in the Finnish pharmaceutical market one year (2004) and five years (2008) after the introduction of GS. Completed questionnaires were returned by 16 original and 7 generic product companies in 2004 (response rate 56%, n = 41) and by 16 original and 6 generic product companies in 2008 (response rate 56%, n = 39). Descriptive statistical analyses were performed. The number of employees (2004: n = 6/16, 2008: n = 7/16) and the amount of prescription medicine marketing (2004: n = 7/16, 2008: n = 8/16) decreased in many of the original product companies after the introduction of GS. GS resulted in problems related to the storage of pharmaceuticals in the original product companies shortly after GS was introduced (p = 0.032 between 2004 and 2008). In the generic product companies, the prescription medicine representatives' visits to pharmacies increased at the beginning of GS (p = 0.021 between 2004 and 2008). In addition, GS caused problems with the storage of pharmaceuticals one year and five years after the reform (2004: n = 4/7, 2008: n = 3/6). The differences between original and generic product companies regarding the impacts of GS were not, however, statistically significant. GS did not affect on the range of sales packages on the market or the research activities of the majority of

  14. Introduction to adaptive arrays

    CERN Document Server

    Monzingo, Bob; Haupt, Randy

    2011-01-01

    This second edition is an extensive modernization of the bestselling introduction to the subject of adaptive array sensor systems. With the number of applications of adaptive array sensor systems growing each year, this look at the principles and fundamental techniques that are critical to these systems is more important than ever before. Introduction to Adaptive Arrays, 2nd Edition is organized as a tutorial, taking the reader by the hand and leading them through the maze of jargon that often surrounds this highly technical subject. It is easy to read and easy to follow as fundamental concept

  15. Effect of the 13-valent pneumococcal conjugate vaccine on invasive pneumococcal disease in England and Wales 4 years after its introduction: an observational cohort study.

    Science.gov (United States)

    Waight, Pauline A; Andrews, Nicholas J; Ladhani, Shamez N; Sheppard, Carmen L; Slack, Mary P E; Miller, Elizabeth

    2015-05-01

    The 13-valent pneumococcal conjugate vaccine (PCV13) protects against key serotypes that increased after routine immunisation with the seven-valent vaccine (PCV7), but its potential for herd protection and serotype replacement is uncertain. The aim of this study was to analyse the effect of the 13-valent pneumococcal conjugate vaccine on invasive pneumococcal disease in England and Wales 4 years after its introduction. We used a national dataset of electronically reported and serotyped invasive pneumococcal disease cases in England and Wales to estimate incidence rate ratios (IRRs) for vaccine and non-vaccine type invasive pneumococcal disease between July, 2013, and June, 2014, versus the pre-PCV13 and pre-PCV7 baseline. Incidence rates were corrected for missing serotype data and changes in surveillance sensitivity over time. An over-dispersed Poisson model was used to estimate IRRs and confidence intervals. Incidence of invasive pneumococcal disease in the epidemiological year 2013/14 decreased by 32% compared with the pre-PCV13 baseline (incidence 10·14 per 100,000 in 2008-10 vs 6·85 per 100,000 in 2013/14; IRR 0·68, 95% CI 0·64-0·72). This was due to an 86% reduction of the serotypes covered by PCV7 (1·46 vs 0·20 per 100,000; IRR 0·14, 0·10-0·18) and a 69% reduction of the additional six serotypes covered by PCV13 (4·48 vs 1·40 per 100,000; IRR 0·31, 0·28-0·35). When compared with the pre-PCV7 baseline, there was a 56% overall reduction in invasive pneumococcal disease (15·63 vs 6·85 per 100,000; IRR 0·44, 95% CI 0·43-0·47). Compared with the pre-PCV13 baseline, the incidence of non-PCV13 serotypes increased (incidence all ages 4·19 vs 5·25 per 100,000; IRR 1·25, 95% CI 1·17-1·35) due to increases across a broad range of serotypes in children younger than 5 years and in people aged 45 years or more. In children younger than 5 years, incidence of non-PCV13 serotypes in 2013/14 was higher than in 2012/13 (age Wales has reduced the

  16. Prevalence of Rotavirus Genotypes in Children Younger than 5 Years of Age before the Introduction of a Universal Rotavirus Vaccination Program: Report of Rotavirus Surveillance in Turkey

    Science.gov (United States)

    Durmaz, Riza; Kalaycioglu, Atila Taner; Acar, Sumeyra; Bakkaloglu, Zekiye; Karagoz, Alper; Korukluoglu, Gulay; Ertek, Mustafa; Torunoglu, Mehmet Ali

    2014-01-01

    Background Group A rotaviruses are the most common causative agent of acute gastroenteritis among children less than 5 years of age throughout the world. This sentinel surveillance study was aimed to obtain baseline data on the rotavirus G and P genotypes across Turkey before the introduction of a universal rotavirus vaccination program. Methods Rotavirus antigen-positive samples were collected from 2102 children less than 5 years of age who attended hospitals participating in the Turkish Rotavirus Surveillance Network. Rotavirus antigen was detected in the laboratories of participating hospitals by commercial serological tests such as latex agglutination, immunochromatographic test or enzyme immunoassay. Rotavirus G and P genotypes were determined by reverse transcription polymerase chain reaction (RT-PCR) using consensus primers detecting the VP7 and VP4 genes, followed by semi-nested type-specific multiplex PCR. Results RT-PCR found rotavirus RNA in 1644 (78.2%) of the samples tested. The highest rate of rotavirus positivity (38.7%) was observed among children in the 13 to 24 month age group, followed by children in the age group of 25 to 36 months (28.3%). A total of eight different G types, six different P types, and 42 different G–P combinations were obtained. Four common G types (G1, G2, G3, and G9) and two common P types (P[8] and P[4]) accounted for 95.1% and 98.8% of the strains, respectively. G9P[8] was the most common G/P combination found in 40.5% of the strains followed by G1P[8] (21.6%), G2P[8] (9.3%), G2P[4] (6.5%), G3P[8] (3.5%), and finally, G4P[8] (3.4%). These six common genotypes included 83.7% of the strains tested in this study. The rate of uncommon genotypes was 14%. Conclusion The majority of the strains analyzed belonged to the G1–G4 and G9 genotypes, suggesting high coverage of current rotavirus vaccines. This study also demonstrates a dramatic increase in G9 genotype across the country. PMID:25437502

  17. Characterization of fifteen SNP markers by mining EST in sea ...

    Indian Academy of Sciences (India)

    Molecular mark- ers are powerful tools for conservation and management of natural resources, and for marker-assisted selection in captive populations. In recent years, SNP have rapidly become the markers ... nonredundant (NR) database using BLASTX (http://blast. ncbi.nlm.nih.gov/Blast.cgi) (cut off E-value of 1.0 × 10.

  18. Jovian discoveries; how Galileo explored the Jovian system fifteen years ago

    NARCIS (Netherlands)

    Willems, T.

    2011-01-01

    Ever since the famous astronomer Galileo Galilei improved his telescope making it possible to look further into space, people have been staring through telescopes into the far distance in search of new worlds. In January 1610 Galilei discovered the four biggest satellites of Jupiter: Io, Europa,

  19. Fifteen years experience with finger arterial pressure monitoring : Assessment of the technology

    NARCIS (Netherlands)

    Imholz, B.P.M.; Wieling, W.; Montfrans, G.A. van; Wesseling, K.H.

    1998-01-01

    We review the Finapres technology, embodied in several TNO-prototypes and in the Ohmeda 2300 and 2300e Finapres NIBP. Finapres is an acronym for FINger Arterial PRESsure, the device delivers a continuous finger arterial pressure waveform. Many papers report on the accuracy of the device in

  20. Fifteen years experience with finger arterial pressure monitoring: assessment of the technology

    NARCIS (Netherlands)

    Imholz, B. P.; Wieling, W.; van Montfrans, G. A.; Wesseling, K. H.

    1998-01-01

    We review the Finapres technology, embodied in several TNO-prototypes and in the Ohmeda 2300 and 2300e Finapres NIBP. Finapres is an acronym for FINger Arterial PRESsure, the device delivers a continuous finger arterial pressure waveform. Many papers report on the accuracy of the device in

  1. Budd Chiari Syndrome in a Fifteen-Year Old Girl with Systemic ...

    African Journals Online (AJOL)

    It is believed that in this patient, Budd Chiari Syndrome resulted from hepatic veinous thrombosis due to the presence of Lupus anticoagulants. As the young girl was suffering from antiphospholipid syndrome secondary to lupus, this milder form of Budd-Chiari Syndrome was later treated in India with surgical shunts.

  2. The policy response to macroeconomic and fiscal imbalances in Italy in the last fifteen years

    Directory of Open Access Journals (Sweden)

    Antonio Bassanetti

    2014-03-01

    Full Text Available This paper reviews the main macroeconomic trends and the debate on policy priorities in Italy since the advent of EMU. It argues that, in the decade up to the outbreak of the global crisis (1998-2007, in Italy the reform process came to a virtual standstill and fiscal policy was inconsistent with the commitments taken on at the European level. The paper suggests that the lack of resolute policy reactions to the institutional dysfunctions and structural weaknesses was due to the fragmentation of the political constituency, while a variety of favourable contingent factors masked the difficulties of the productive system. Had Italy been better positioned in terms of public finances and structural features in 2007, some of the adverse effects of the global and sovereign crises would have been avoided.

  3. Changes to the Fossil Record of Insects through Fifteen Years of Discovery.

    Directory of Open Access Journals (Sweden)

    David B Nicholson

    Full Text Available The first and last occurrences of hexapod families in the fossil record are compiled from publications up to end-2009. The major features of these data are compared with those of previous datasets (1993 and 1994. About a third of families (>400 are new to the fossil record since 1994, over half of the earlier, existing families have experienced changes in their known stratigraphic range and only about ten percent have unchanged ranges. Despite these significant additions to knowledge, the broad pattern of described richness through time remains similar, with described richness increasing steadily through geological history and a shift in dominant taxa, from Palaeoptera and Polyneoptera to Paraneoptera and Holometabola, after the Palaeozoic. However, after detrending, described richness is not well correlated with the earlier datasets, indicating significant changes in shorter-term patterns. There is reduced Palaeozoic richness, peaking at a different time, and a less pronounced Permian decline. A pronounced Triassic peak and decline is shown, and the plateau from the mid Early Cretaceous to the end of the period remains, albeit at substantially higher richness compared to earlier datasets. Origination and extinction rates are broadly similar to before, with a broad decline in both through time but episodic peaks, including end-Permian turnover. Origination more consistently exceeds extinction compared to previous datasets and exceptions are mainly in the Palaeozoic. These changes suggest that some inferences about causal mechanisms in insect macroevolution are likely to differ as well.

  4. Analysis and fifteen-year projection of the market for LANDSAT data

    Science.gov (United States)

    1981-01-01

    The potential market for LANDSAT products through the 1990's was determined. Results are presented in a matrix format. Improved resolution is a major factor in the marketability of LANDSAT data, the 10 meter resolution (projected for 1995) having a significant impact on the federal, private, and international users, and on the agricultural, minerals, and national defense applications. Data delivery time and competition from the French remote sensing system are considered.

  5. Fifteen years of detaining children who seek asylum in Australia - evidence and consequences.

    Science.gov (United States)

    Mares, Sarah

    2016-02-01

    To review and summarise the evidence about and consequences of Australia's policy of mandatory indefinite detention of children and families who arrive by boat to seek asylum. This paper will summarise the accumulated scientific evidence about the health and mental health impacts of immigration detention on children and compare methodologies and discuss the political reception of the 2004 and 2014 Australian Human Rights Commission (AHRC) Inquiries into Immigration Detention of children. The conclusions of the 2004 and 2014 Inquiries into Immigration Detention of Children are consistent with Australian and international research which demonstrates that immigration detention has harmful health, mental health and developmental consequences for children and negative impacts on parenting. The evidence that prolonged immigration detention causes psychological and developmental harm to children and families and is in breach of Australia's human rights obligations is consistent. This is now partially acknowledged by the Government. Attempts to limit public scrutiny through reduced access and potential punishment of medical witnesses arguably indicates the potency of their testimony. These harmful and unethical policies should be opposed. © The Royal Australian and New Zealand College of Psychiatrists 2015.

  6. Changes to the Fossil Record of Insects through Fifteen Years of Discovery

    Science.gov (United States)

    Nicholson, David B.; Mayhew, Peter J.; Ross, Andrew J.

    2015-01-01

    The first and last occurrences of hexapod families in the fossil record are compiled from publications up to end-2009. The major features of these data are compared with those of previous datasets (1993 and 1994). About a third of families (>400) are new to the fossil record since 1994, over half of the earlier, existing families have experienced changes in their known stratigraphic range and only about ten percent have unchanged ranges. Despite these significant additions to knowledge, the broad pattern of described richness through time remains similar, with described richness increasing steadily through geological history and a shift in dominant taxa, from Palaeoptera and Polyneoptera to Paraneoptera and Holometabola, after the Palaeozoic. However, after detrending, described richness is not well correlated with the earlier datasets, indicating significant changes in shorter-term patterns. There is reduced Palaeozoic richness, peaking at a different time, and a less pronounced Permian decline. A pronounced Triassic peak and decline is shown, and the plateau from the mid Early Cretaceous to the end of the period remains, albeit at substantially higher richness compared to earlier datasets. Origination and extinction rates are broadly similar to before, with a broad decline in both through time but episodic peaks, including end-Permian turnover. Origination more consistently exceeds extinction compared to previous datasets and exceptions are mainly in the Palaeozoic. These changes suggest that some inferences about causal mechanisms in insect macroevolution are likely to differ as well. PMID:26176667

  7. Training medical students in human rights: a fifteen-year experience in Geneva

    Directory of Open Access Journals (Sweden)

    Philippe Chastonay

    2012-09-01

    Full Text Available Background: Training health professionals in the field of human rights has long been advocated by the United Nations. Over the past decade some medical schools have introduced health and human rights courses, yet by far not all. This paper describes the objectives and the content of the Health and Human Rights program developed at the Faculty of Medicine, University of Geneva. Methods: The health and human rights program was developed through the identification of the course objectives, contents, and educational modalities using consensus techniques, and through a step by step implementation procedure integrating multiple evaluation processes. Results: Defined objectives included the familiarization with the concepts, instruments and mechanisms of human rights, the links between health and human rights, and the role of health professionals in promoting human rights. The content ultimately adopted focused on the typology of human rights, their mechanisms of protection, their instruments, as well as social inequalities and vulnerable groups of the population. The implementation proceeded through a step by step approach. Evaluation showed high satisfaction of students, good achievement of learning objectives, and some academic and community impact. Conclusions: High interest of students for a human rights course is encouraging. Furthermore, the community projects initiated and implemented by students may contribute to the social responsibility of the academic institution.

  8. High grade angiosarcoma fifteen years after breast conservation therapy with radiation therapy: A case report

    Directory of Open Access Journals (Sweden)

    William Boyan, Jr.

    2014-01-01

    CONCLUSION: Secondary breast angiosarcoma diagnosis requires frequent follow ups and a high index of suspicion. With mastectomy giving the best chance of treatment in these cases, early detection is crucial in this rare sequela.

  9. Fifteen-Year Journey to High Reliability in Pathology and Laboratory Medicine.

    Science.gov (United States)

    Middleton, Lavinia P; Phipps, Ron; Routbort, Mark; Prieto, Victor; Medeiros, L Jeffrey; Riben, Michael; Contreras, Alejandro; Kelley, James; Patel, Keyur; Bingham, John; Wagar, Elizabeth A

    2018-02-01

    Many high-reliability organizations in industries outside of health care have sustained high levels of excellence and prevention of harm while managing complex systems and risk. To date, no health care organizations has organized its efforts to achieve highly reliable results despite several decades of improvement science. Laboratorians were early adopters of quality initiatives and process improvements. In the late 1990s, the Division of Pathology and Laboratory Medicine at The University of Texas MD Anderson Cancer Center embarked on a major effort to improve quality and patient safety and to reduce waste. This article describes the institution's journey toward approaching high reliability with the intent to share not only the tools and best practices, but also the ongoing reassessment of the problems detected on the journey. The authors hope that their experience will help the reader develop interventions to adapt in their own environment to facilitate more optimal patient care.

  10. Fifteen-year follow-up of quality of life in type 1 diabetes mellitus

    NARCIS (Netherlands)

    van Dijk, Peter R; Logtenberg, Susan Jj; Groenier, Klaas H; Keers, Joost C; Bilo, Henk Jg; Kleefstra, Nanne

    2014-01-01

    AIM: To evaluate metabolic control and health-related quality of life (HRQOL) in a type 1 diabetes mellitus (T1DM) population. METHODS: As part of a prospective cohort study, 283 T1DM patients treated with various insulin treatment modalities including multiple daily injections (MDI) and continuous

  11. Changes to the Fossil Record of Insects through Fifteen Years of Discovery.

    Science.gov (United States)

    Nicholson, David B; Mayhew, Peter J; Ross, Andrew J

    2015-01-01

    The first and last occurrences of hexapod families in the fossil record are compiled from publications up to end-2009. The major features of these data are compared with those of previous datasets (1993 and 1994). About a third of families (>400) are new to the fossil record since 1994, over half of the earlier, existing families have experienced changes in their known stratigraphic range and only about ten percent have unchanged ranges. Despite these significant additions to knowledge, the broad pattern of described richness through time remains similar, with described richness increasing steadily through geological history and a shift in dominant taxa, from Palaeoptera and Polyneoptera to Paraneoptera and Holometabola, after the Palaeozoic. However, after detrending, described richness is not well correlated with the earlier datasets, indicating significant changes in shorter-term patterns. There is reduced Palaeozoic richness, peaking at a different time, and a less pronounced Permian decline. A pronounced Triassic peak and decline is shown, and the plateau from the mid Early Cretaceous to the end of the period remains, albeit at substantially higher richness compared to earlier datasets. Origination and extinction rates are broadly similar to before, with a broad decline in both through time but episodic peaks, including end-Permian turnover. Origination more consistently exceeds extinction compared to previous datasets and exceptions are mainly in the Palaeozoic. These changes suggest that some inferences about causal mechanisms in insect macroevolution are likely to differ as well.

  12. The final fifteen feet of hose : the Canadian gasoline industry in the year 2000

    International Nuclear Information System (INIS)

    Sperber, M.; Beckman, K.; Clavet, F.; Bernard, M.-C.; Bussiere, L.; Frank, J.; Lefebvre, M.

    2001-01-01

    An up-to-date profile of the Canadian gasoline industry was presented with an effort to address some of the preoccupations of industry stakeholders and the perceptions of Canadian motorists. This study provides new insights into the workings of the industry by providing a balanced perspective on the many contentious issues that affect the industry, particularly retail pricing. The Conference Board's empirical analysis makes use of a new approach which provides a better understanding of how retail prices react to changes in wholesale prices. Competition is the reason why a retail market outcome margin exists in each city based on local conditions. This margin is the basis for price changes in that market and reflects a margin at which most competitors are able to sustain themselves. When changes occur in the wholesale price of crude, the retail price is adjusted depending on whether the actual margin in place is higher or lower than the market outcome margin. Crude oil and taxes make up about 84 per cent of the average price of a litre of regulated unleaded gasoline. The main reason for rising Canadian gasoline prices is the rapid increase in world crude oil prices. The volatility in gasoline prices is a direct result of the competitive nature of the business at the street level and the uniformity of prices reflects the rapid response of individual dealers to the actions of their competitors. Each outlet has fixed costs to cover, therefore average sales volumes per outlet have an important impact on retail margins and prices. It was also emphasized that there is no empirical proof that gasoline prices increase before long weekends, nor is there any proof of asymmetry in price adjustment in the retail market. It was noted that the price of gasoline in Canada and the United States, excluding taxes, is very similar. 15 tabs., 59 figs

  13. A Break with History : Fifteen Years of Inequality Reduction in Latin America

    OpenAIRE

    World Bank

    2011-01-01

    In 2004 the World Bank released a regional report titled 'Inequality in Latin America: Breaking with History?' Analyzing data from the early 1990s to the early 2000s, a period in which many countries in the region were experiencing increasing inequality, this study raised the question of whether Latin America could reverse its historical pattern of high and persistent inequality. The repor...

  14. Fifteen Years On: An Examination of the Irish Famine Curricula in New York and New Jersey

    Science.gov (United States)

    Feeley, Christopher J.

    2014-01-01

    Since the early 1980s Holocaust education and genocide studies programs at the primary, secondary and post-secondary educational levels have become commonplace and an accepted element of public school curriculum. As these programs and their curricula gained acceptance within public education, efforts to increase awareness of genocidal events…

  15. Fifteen Years of Research on PISA Effects on Education Governance: A Critical Review

    Science.gov (United States)

    Pons, Xavier

    2017-01-01

    This article provides a literature review on the effects of the OECD's Programme for International Student Assessment (PISA) on education governance and policy process across participating countries. This review seemed necessary because there has been a growing body of literature on this topic since 2003, especially since 2010, because this…

  16. The Agri-food Competitive Performance in the EU Countries: A Fifteen Years Retrospective

    OpenAIRE

    Carraresi, Laura; Banterle, Alessandro

    2013-01-01

    The purpose of this paper is to evaluate the competitive performance of different European countries at sector level in the intra-EU market from 1995 to 2011, comparing food industry and agricultural sector. In particular, we aim to assess the effect of the EU enlargement (first period) and the economic crisis (second period) on the competitiveness of EU countries. The data come from the Eurostat database of international trade. The competitive performance of EU countries is measured through ...

  17. Comparing Apples and Oranges: Fifteen Years of Definitions of Giftedness in Research

    Science.gov (United States)

    Carman, Carol A.

    2013-01-01

    The lack of a unified definition of giftedness leads researchers to use very different operationalizations when selecting a sample of gifted individuals for use in research. We found 104 empirical articles from 38 journals that differentiated between gifted and nongifted students which were analyzed to determine the most common methods of…

  18. The Non-Proliferation Treaty: Fifteen years after entry into force

    International Nuclear Information System (INIS)

    1985-01-01

    The need to halt a wider spread of nuclear weapons grew out of the realization that the increase in the number of countries possessing such weapons would increase the threat to world security. As the Treaty on the Non-Proliferation of Nuclear Weapons clearly states in its preamble, the proliferation of nuclear weapons would seriously enhance the danger of nuclear war. The Treaty - also known as the non-proliferation Treaty - was concluded in 1968, at a time when there were already five nuclear-weapon Powers: the United States, the Soviet Union, the United Kingdom, France and China. This fact sheet is intended to provide background material on the Treaty, including the events that led to its conclusion, an overview of its provisions and the developments at the two previously held Review Conferences

  19. Electric vehicles in France: A fifteen-year financing plan for massive roll-out

    International Nuclear Information System (INIS)

    Sartor, Oliver; Spencer, Thomas; Fryatt, Oliver

    2017-03-01

    Numerous studies have acknowledged the importance of massive deployment of full battery electric vehicles (BEVs) and plug-in hybrid vehicles (PHEVs), in order to reduce environmental externalities from personal road transport, in particular CO 2 emissions. Good news about declining battery costs and ambitious output pronouncements by major car manufacturers may give the misleading impression that mass-penetration of EVs is just around the corner. But current deployment rates of EVs are significantly off track for deep decarbonization of the French transport system by 2050. In the short to medium term, large scale penetration is far from assured, unless there are further policies to address a number of barriers. In the short term to around 2020-2025, EVs will remain more expensive to purchase and run than equivalent internal combustion engine (ICE) vehicles. In the medium term beyond 2020-2025, EVs are likely to become competitive on a lifetime cost basis. However, they may still confront other financing challenges, such as higher upfront purchase costs (as opposed to lifetime costs). This barrier may be particularly important if consumers are myopic and discount future fuel savings, or if they are credit constrained. In the longer run, EVs will create other challenges for governments to deal with, such as fuel tax revenue erosion. EV support policy should therefore be designed with a dynamic, at least decadal perspective. In this paper, we consider a three-phase financing strategy corresponding to the above described challenges. A range of fiscal policy tools are likely to be needed as part of any feasible regulatory framework for supporting massive EV roll out. But this raises the critical issue of the distributional impacts of the transition to EVs. The upfront financing challenge may be particularly relevant for lower income households, while at the same time, massive roll-out of EVs will require that middle and lower income households start to purchase electric vehicles. This requires that policy consider how to ensure access to EVs for such consumers. The progressive compensation of declining fuel tax revenues through fuel tax increases and the ratcheting up of malus policies on ICEs could also have important distributional impacts. Thus EV support policy should also be designed and monitored with distributional impacts in mind. The EV financing challenge is eminently feasible, and we can be optimistic about the capacity of a judicious policy mix to push the massive deployment of EVs. However, one should not be deluded by the hype currently surrounding EVs: rapid deployment will not occur without a further policy. This policy push should be fiscally neutral if possible; be phased out once the technology reaches maturity; and pay attention to the distributional aspects of policy

  20. Fifteen Years of Web Based Data Management at Tooele Army Depot

    Science.gov (United States)

    2012-03-28

    And, Tooele Army Depot Goes Online Following an EPA audit of nine federal  facilities, Tooele Army Depot ( TEAD )  proactively begins the process of...District contracted with  Synectics to provide an innovative solution  allowing  TEAD  stakeholders to access the same  data the prime contractor was...Ellin, do you know llle project Suzan Hughes document for Parson’s TEAD SVYMU-58 Certified All the Data in One Place Laboratories & Contractors Legend

  1. Meta-Interpretation: Fifteen Years of Research with the Management Report

    Directory of Open Access Journals (Sweden)

    Uajará Pessoa Araújo

    2016-08-01

    Full Text Available ABSTRACT This paper deals with Brazilian empirical research published in journals between 2000 and mid-2015 that used, as a source of data, the Management Reports (MRs released by publicly-traded companies together with their financial statements. MRs differ from each other, both in form as well as in substance, and due to this as well as to their other characteristics, they prove attractive for academic studies interested in official company discourse, more so because they involve documents that are public and retrievable over time, covering a substantial range of typically larger companies from different economic sectors. Driven by these characteristics, the goal of this study was to understand the way the academic world understands and uses the MR. The paper favored an interpretivist viewpoint, but used the triangulation allowed by the use of qualitative (content analysis and quantitative (statistical, sociometric, and bibliometric analyses methods. It was concluded that, for the core group of experts who dealt with the document, the MR is biased, incomplete, questionable, unclear, laborious, uncertain, but also useful - in the absence of another -, comprehensive, available, and retrievable over time. And it lends itself to the interest of company directors by increasing their value and at the same time legitimizing their companies, incorporating into discourse the use of contemporary management practices, consistent with the expectations of stakeholders. Finally, it suggests the possibility, unexplored in the articles analyzed, of employing the MR to study the dynamics of the institutionalization of administrative practices among companies in the country.

  2. Abstract Introduction

    African Journals Online (AJOL)

    Tree heights qnti.:c,a'1- opy diameters were recorded three years after planting. : The. results showed !harthe. growth of Jheseetj- lings was more vigorous than the ... the first stage in the Tanzahian-cashew bf~ed~ .... -girigusing"inolecular markers, in order to im- ' tionally selected as l!',clone,which appeared to be.

  3. Introduction pages

    Directory of Open Access Journals (Sweden)

    Radu E. Sestras

    2015-09-01

    Full Text Available Introduction Pages and Table of Contents Research ArticlesInsulin Requirements in Relation to Insulin Pump Indications in Type 1 DiabetesPDFGabriela GHIMPEŢEANU,\tSilvia Ş. IANCU,\tGabriela ROMAN,\tAnca M. ALIONESCU259-263Comparative Antibacterial Efficacy of Vitellaria paradoxa (Shea Butter Tree Extracts Against Some Clinical Bacterial IsolatesPDFKamoldeen Abiodun AJIJOLAKEWU,\tFola Jose AWARUN264-268A Murine Effort Model for Studying the Influence of Trichinella on Muscular Activity of MicePDFIonut MARIAN,\tCălin Mircea GHERMAN,\tAndrei Daniel MIHALCA269-271Prevalence and Antibiogram of Generic Extended-Spectrum β-Lactam-Resistant Enterobacteria in Healthy PigsPDFIfeoma Chinyere UGWU,\tMadubuike Umunna ANYANWU,\tChidozie Clifford UGWU,\tOgbonna Wilfred UGWUANYI272-280Index of Relative Importance of the Dietary Proportions of Sloth Bear (Melursus ursinus in Semi-Arid RegionPDFTana P. MEWADA281-288Bioaccumulation Potentials of Momordica charantia L. Medicinal Plant Grown in Lead Polluted Soil under Organic Fertilizer AmendmentPDFOjo Michael OSENI,\tOmotola Esther DADA,\tAdekunle Ajayi ADELUSI289-294Induced Chitinase and Chitosanase Activities in Turmeric Plants by Application of β-D-Glucan NanoparticlesPDFSathiyanarayanan ANUSUYA,\tMuthukrishnan SATHIYABAMA295-298Present or Absent? About a Threatened Fern, Asplenium adulterinum Milde, in South-Eastern Carpathians (RomaniaPDFAttila BARTÓK,\tIrina IRIMIA299-307Comparative Root and Stem Anatomy of Four Rare Onobrychis Mill. (Fabaceae Taxa Endemic in TurkeyPDFMehmet TEKİN,\tGülden YILMAZ308-312Propagation of Threatened Nepenthes khasiana: Methods and PrecautionsPDFJibankumar S. KHURAIJAM,\tRup K. ROY313-315Alleviate Seed Ageing Effects in Silybum marianum by Application of Hormone Seed PrimingPDFSeyed Ata SIADAT,\tSeyed Amir MOOSAVI,\tMehran SHARAFIZADEH316-321The Effect of Halopriming and Salicylic Acid on the Germination of Fenugreek (Trigonella foenum-graecum under Different Cadmium

  4. Squamous cell carcinoma of the conjunctiva: analysis of fifteen cases

    International Nuclear Information System (INIS)

    Baig, M.S.A.; Dareshani, S.; Ali, M.A.; Khan, M.S.

    2009-01-01

    To document various clinical presentations and management options of conjunctival squamous cell carcinoma (CSCC) in patients attending ophthalmic out patients department (OPD) of a tertiary care centre. This case series was carried out in the Department of Ophthalmology Civil Hospital and, Dow University of Health Sciences, Karachi and were reviewed from June 2004 to December 2007. Socio-demographic data and clinical features of patients with biopsy proven conjunctival squamous cell carcinoma were recorded and analysed. All patients underwent complete ophthalmic examination by a fellow ophthalmologist and clinical findings were recorded on a prescribed Performa. Data was analysed in terms of frequency, means and median by SPSS for windows V.15. Seventy-two percent of the patients were male and 28% were female, more than 80% of patients were in the age group of seventy years and above. Eighteen percent of patients developed intraocular invasion and the eyes had to be enucleated. CSCC occurs in sun damaged ocular surface usually at limbus, elderly men are more commonly involve, recurrence is a feature of disease and high risk in older individual. In our treatment we used various therapies, excision with clear margin, topical mitomycin C adjunctive cryotherapy and amniotic graft. (author)

  5. Professionalism: introduction

    Directory of Open Access Journals (Sweden)

    Raschke RA

    2014-05-01

    Full Text Available No abstract available. Article truncated at 150 words. An important event in my career occurred about 20 years ago, late on a Friday afternoon. I was scheduled on call in the ICU for the entire 72-hour weekend, and even though I was just getting started, I was already tired and in a lousy mood. At 5 PM, I got a consult to see a patient in the neuro ICU. He was a 34-year-old man who had attempted suicide by drinking ethylene glycol antifreeze after an argument with his girlfriend. He had initially stabilized from a medical standpoint, but then developed delayed-onset cerebral edema. The team that was taking care of him had unsuccessfully pursued all treatment options. After 8 days of effort, he remained in a deep coma, near brain death. Now, with nothing left to try, and no hope left for a good outcome, they were dumping responsibility onto me just in time for the weekend. I ...

  6. Introduction of interdisciplinary teaching: two case studies : commentary on "teaching science, technology, and society to engineering students: a sixteen year journey".

    Science.gov (United States)

    Spitzer, Hartwig

    2013-12-01

    Interdisciplinary courses on science, engineering and society have been successfully established in two cases, at Bilkent University, Ankara, Turkey, and at the University of Hamburg, Germany. In both cases there were institutional and perceptual barriers that had to be overcome in the primarily disciplinary departments. The ingredients of success included a clear vision of interdisciplinary themes and didactics, and the exploitation of institutional opportunities. Haldun M. Ozaktas in Ankara used the dynamics of an accreditation process to establish courses on engineering and society. At the University of Hamburg the introduction of optional courses into all curricula allowed for the establishment of a seminar series on physics and society, as well as on peace education and peace building. Both of these approaches have a weakness in common: the courses can disappear once their initiators have left, unless the interdisciplinary themes are integrated into compulsory core curricula.

  7. The so-called unresolved Osgood-Schlatter lesion: a concept based on fifteen surgically treated lesions.

    Science.gov (United States)

    Mital, M A; Matza, R A; Cohen, J

    1980-07-01

    Of 118 patients with 151 knees treated for Osgood-Schlatter disease, fourteen patients (fifteen knees) had a distinct and separate ossicle at the proximal aspect of the tibial tubercle. This ossicle appeared after the child was first seen in all but three of the fifteen knees. When the ossicle failed to unite with the tubercle, the non-union was associated with local discomfort during activity and when direct pressure was applied on the tubercle. The symptoms did not respond to conservative treatment for an average of 3.8 years. Resection of the ossicle along with the adjacent bursa was followed by prompt relief of symptoms. Histological studies showed no evidence of avascularity. All ossicles were attached to the distal part of the undersurface of the ligamentum patellae and were separated from the tubercle by a bursa or scar tissue. The findings strongly support the concept that avulsion of the proximal cartilaginous part of the tibial tubercle is the cause of Osgood-Schlatter disease and they also suggest that once a separate ossicle is formed and becomes symptomatic, surgical excision is necessary to relieve the symptoms.

  8. Introduction to modern cryptography

    CERN Document Server

    Katz, Jonathan

    2014-01-01

    Praise for the First Edition:""This book is a comprehensive, rigorous introduction to what the authors name 'modern' cryptography. … a novel approach to how cryptography is taught, replacing the older, construction-based approach. … The concepts are clearly stated, both in an intuitive fashion and formally. … I would heartily recommend this book to anyone who is interested in cryptography. … The exercises are challenging and interesting, and can benefit readers of all academic levels.""-IACR Book Reviews, January 2010""Over the past 30 years, cryptography has been transformed from a mysterious

  9. Theoretical Optics An Introduction

    CERN Document Server

    Römer, Hartmann

    2004-01-01

    Starting from basic electrodynamics, this volume provides a solid, yet concise introduction to theoretical optics, containing topics such as nonlinear optics, light-matter interaction, and modern topics in quantum optics, including entanglement, cryptography, and quantum computation. The author, with many years of experience in teaching and research, goes way beyond the scope of traditional lectures, enabling readers to keep up with the current state of knowledge. Both content and presentation make it essential reading for graduate and phD students as well as a valuable reference for researche

  10. Comparison of the ability of fifteen onion (Allium cepa L. cultivars to accumulate nitrates

    Directory of Open Access Journals (Sweden)

    Renata Wojciechowska

    2014-04-01

    Full Text Available The aim of a two-year study was to characterise selected Allium cepa L. genotypes with regard to their ability to accumulate nitrates in bulbs as well as to search for a possible relation between NO3- concentration and dry matter content. Fifteen cultivars of edible onion, mostly of long-day genotype with different growing periods, bulb size and skin colour, were taken for the experiment. Seeds of particular cultivars were obtained from the following seed companies: Spójnia Nochowo (‘Labrador’, ‘Takstar F1’,‘Tęcza’, ‘Warna’, ‘Zorza’, Polan (‘Polanowska’, ‘Topolska’, PlantiCo Gołębiew (‘Alibaba’, ‘Efekt’, ‘Kristine’, ‘Niagara F1’,and PlantiCo Zielonki (‘Bila’, ‘Irka’, ‘Wenta’, ‘Zeta’. Plants produced from seedlings were grown in the experimental field of the University of Agriculture in Kraków. After crop harvesting and additional drying, nitrate and dry matter content in bulbs of all cultivars were measured. The following cultivars: ‘Efekt’, ‘Labrador’ and red-skinned ‘Wenta’, were characterized by the lowest ability to accumulate NO3- in bulbs. The highest nitrate content was noted in bulbs of ‘Takstar F1’ (a very early-season cultivar, followed by ‘Bila’ and ‘Tęcza’. A weak, yet statistically significant negative correlation between nitrate and dry matter content was observed. The highest dry matter content was determined in bulbs of white-skinned ‘Alibaba’, while the lowest – in brown-skinned ‘Labrador’.

  11. Decline of Neurologic Varicella Complications in Children During the First Seven Years After Introduction of Universal Varicella Vaccination in Germany, 2005-2011.

    Science.gov (United States)

    Streng, Andrea; Grote, Veit; Rack-Hoch, Anita; Liese, Johannes G

    2017-01-01

    Universal varicella vaccination for 1-year-old children was introduced in Germany in 2004. We investigated changes in the incidence and type of varicella-associated neurologic complications in children during the first 7 years after universal vaccination recommendation. A surveillance study was conducted based on patients linear trend across years was assessed by Poisson regression models. Of a total of 1263 varicella-associated pediatric hospitalizations, 228 children (18.1%) had neurologic complications (median age 4 years, interquartile range 2-7; 56% male). The most frequent neurologic complications were febrile convulsion (32.0% of 228 children, median age 3.0 years), varicella encephalitis or meningitis (28.9%; median age 4.5 years), syncope (13.2%; median age 7.0 years) and cerebral convulsion (11.0%; median age 4.0 years). Other complications included ataxia (3.1%), facial nerve palsy (2.6%) and cerebral vasculitis/infarction (1.8%). Neurologic complications showed a continuous decrease between 2005 and 2011, from an incidence of 2.8 (95% confidence interval: 2.1-3.6) per 100,000 children <17 years of age to 1.2 (95% confidence interval: 0.7-2.1; P < 0.001). In particular, a marked decline was observed among children up to 7 years of age, mainly because of a decrease in the number of febrile convulsions and encephalitis or meningitis. The incidence of varicella-associated neurologic complications in children decreased approximately by 60% during the first 7 years following the recommendation for universal vaccination.

  12. Vigour and behaviour of fifteen citrus varieties against tristeza in the ...

    African Journals Online (AJOL)

    SERVER

    2007-06-18

    Jun 18, 2007 ... Fifteen varieties or combinations of citrus (lime, grapefruit, lemons, oranges, mandarin and hybrids) were characterized in the forest ... Satsuma mandarin, Lisbon lemon, Eureka lemon and in some aspects Tahiti lime showed a ... are abnormally gorged with water (Aubert, 1982). The notation scale includes ...

  13. Historical and contemporary environmental context for the Saline-Fifteen site (3BR119)

    Science.gov (United States)

    Don C. Bragg; Hope A. Bragg

    2016-01-01

    This paper summarizes the historical environmental context of the Saline-Fifteen site (3BR119) in Bradley County, Arkansas, developed from the General Land Office (GLO) public land surveys, other old documents, and an examination of current forest inventories and modern research to approximate past environmental attributes for this locality. While an imperfect source...

  14. Fifteen-Month-Old Infants Match Vocal Cues to Intentional Actions

    Science.gov (United States)

    Hoicka, Elena; Wang, Su-hua

    2011-01-01

    Fifteen-month-old infants detected a violation when an actor performed an action that did not match her preceding vocal cue: The infants looked reliably longer when the actor expressed a humorous vocal cue followed by a sweet action or expressed a sweet vocal cue followed by a humorous action, than when the vocal cue was followed by a matching…

  15. Evaluation of the effect of the herpes zoster vaccination programme 3 years after its introduction in England: a population-based study.

    Science.gov (United States)

    Amirthalingam, Gayatri; Andrews, Nick; Keel, Philip; Mullett, David; Correa, Ana; de Lusignan, Simon; Ramsay, Mary

    2018-02-01

    In 2013, a herpes zoster vaccination programme was introduced in England for adults aged 70 years with a phased catch-up programme for those aged 71-79 years. We aimed to evaluate the effect of the first 3 years of the vaccination programme on incidence of herpes zoster and postherpetic neuralgia in this population. In this population-based study, we extracted data from the Royal College of General Practitioners sentinel primary care network on consultations with patients aged 60-89 years for herpes zoster and postherpetic neuralgia occurring between Oct 1, 2005, and Sept 30, 2016, obtaining data from 164 practices. We identified individual data on herpes zoster vaccinations administered and consultations for herpes zoster and postherpetic neuralgia, and aggregated these data to estimate vaccine coverage and incidence of herpes zoster and postherpetic neuralgia consultations. We defined age cohorts to identify participants targeted in each year of the programme, and as part of the routine or catch-up programme. We modelled incidence according to age, region, gender, time period, and vaccine eligibility using multivariable Poisson regression with an offset for person-years. Our analysis included 3·36 million person-years of data, corresponding to an average of 310 001 patients aged 60-89 years who were registered at an RCGP practice each year. By Aug 31, 2016, uptake of the vaccine varied between 58% for the recently targeted cohorts and 72% for the first routine cohort. Across the first 3 years of vaccination for the three routine cohorts, incidence of herpes zoster fell by 35% (incidence rate ratio 0·65 [95% 0·60-0·72]) and of postherpetic neuralgia fell by 50% (0·50 [0·38-0·67]). The equivalent reduction for the four catch-up cohorts was 33% for herpes zoster (incidence rate ratio 0·67 [0·61-0·74]) and 38% for postherpetic neuralgia (0·62 [0·50-0·79]). These reductions are consistent with a vaccine effectiveness of about 62% against herpes zoster

  16. Changes in Reef Fish Abundances Associated with the Introduction of Indo-Pacific Lionfish to the Florida Keys National Marine Sanctuary: a Twenty Year Time Series.

    Science.gov (United States)

    Hepner, M.; Muller-Karger, F. E.; Gittings, S.; Stallings, C.

    2016-02-01

    The Marine Biodiversity Observation Network (MBON) is a partnership between academic, private, and government researchers seeking to understand how marine biodiversity changes over long periods of time. In this context, a study of the multi-agency Reef Visual Census (RVC) data, collected over twenty years in the Florida Keys National Marine Sanctuary (FKNMS), was analyzed to measure possible changes in reef fish abundances as a result of possible predation by lionfish predation or due to related trophic cascading. Lionfish were first sighted in the FKNMS in January 2009, with abundances and frequency of occurrence increasing three to six fold throughout the sanctuary by 2011. Their high consumption rates of smaller fish, coupled with their rapidly increasing densities may be having a significant effect on coral reef fish communities. The study compares the natural variability in reef fish abundances from 1994-2009 in the FKNMS, 15 years prior to the first lionfish detected in the sanctuary, to changes in reef fish abundances 5 years after the invasion. The MBON project also aims to develop environmental DNA (eDNA) technology for conducting biodiversity assessments. eDNA is an emerging technique that seeks to quantify biodiversity in an area by obtaining genetic material directly from environmental samples (soil, sediment, water, etc.) without any obvious signs of biological source material. All marine organisms shed DNA into their surrounding habitat, leaving a "fingerprint." Similar to forensic science, the DNA can be collected from seawater and analyzed to determine what species were recently present. The MBON team is evaluating whether eDNA can be used to adequately monitor reef fish biodiversity in coral reef ecosystems. We will compare species detected in our samples to the taxonomic composition of reef fish communities at the sample site as recorded over the past twenty years in the Reef Visual Census data.

  17. Introduction to Pulmonary Fibrosis

    Science.gov (United States)

    ... Events Become An Advocate Volunteer Ways To Give Pulmonary Fibrosis www.lung.org > Lung Health and Diseases > ... Pulmonary Fibrosis > Introduction Share this page: Introduction to Pulmonary Fibrosis What Is Pulmonary Fibrosis? Pulmonary fibrosis is ...

  18. Changes in the incidence of pneumonia, bacterial meningitis, and infant mortality 5 years following introduction of the 13-valent pneumococcal conjugate vaccine in a "3+0" schedule.

    Science.gov (United States)

    Becker-Dreps, Sylvia; Blette, Bryan; Briceño, Rafaela; Alemán, Jorge; Hudgens, Michael G; Moreno, Gilberto; Ordoñez, Ana; Rocha, Julio; Weber, David J; Amaya, Erick

    2017-01-01

    Streptococcus pneumoniae causes about 826,000 deaths of children in the world each year and many health facility visits. To reduce the burden of pneumococcal disease, many nations have added pneumococcal conjugate vaccines to their national immunization schedules. Nicaragua was the first country eligible for GAVI Alliance funding to introduce the 13-valent pneumococcal conjugate vaccine (PCV13) in 2010, provided to infants at 2, 4, and 6 months of age. The goal of this study was to evaluate the population impact of the first five years of the program. Numbers of visits for pneumonia, pneumonia-related deaths, and bacterial meningitis in both children and adults, and infant deaths between 2008 and 2015 were collected from all 107 public health facilities in León Department. Vital statistics data provided additional counts of pneumonia-related deaths that occurred outside health facilities. Adjusted incidence rates and incidence rate ratios (IRRa) in the vaccine (2011-2015) and pre-vaccine periods (2008-2010) were estimated retrospectively using official population estimates as exposure time. The IRRa for pneumonia hospitalizations was 0.70 (95% confidence interval [CI]: 0.66, 0.75) for infants, and 0.92 (95% CI: 0.85, 0.99) for one year-olds. The IRRa for post-neonatal infant mortality was 0.56 (95% CI: 0.41, 0.77). In the population as a whole, ambulatory visits and hospitalizations for pneumonia, as well as pneumonia-related mortality and rates of bacterial meningitis were lower in the vaccine period. During the first five years of program implementation, reductions were observed in health facility visits for pneumonia in immunized age groups and infant mortality, which would be hard to achieve with any other single public health intervention. Future study is warranted to understand whether the lack of a booster dose (e.g., at 12 months) may be responsible for the small reductions in pneumonia hospitalizations observed in one year-olds as compared to infants.

  19. Changes in the incidence of pneumonia, bacterial meningitis, and infant mortality 5 years following introduction of the 13-valent pneumococcal conjugate vaccine in a "3+0" schedule.

    Directory of Open Access Journals (Sweden)

    Sylvia Becker-Dreps

    Full Text Available Streptococcus pneumoniae causes about 826,000 deaths of children in the world each year and many health facility visits. To reduce the burden of pneumococcal disease, many nations have added pneumococcal conjugate vaccines to their national immunization schedules. Nicaragua was the first country eligible for GAVI Alliance funding to introduce the 13-valent pneumococcal conjugate vaccine (PCV13 in 2010, provided to infants at 2, 4, and 6 months of age. The goal of this study was to evaluate the population impact of the first five years of the program.Numbers of visits for pneumonia, pneumonia-related deaths, and bacterial meningitis in both children and adults, and infant deaths between 2008 and 2015 were collected from all 107 public health facilities in León Department. Vital statistics data provided additional counts of pneumonia-related deaths that occurred outside health facilities. Adjusted incidence rates and incidence rate ratios (IRRa in the vaccine (2011-2015 and pre-vaccine periods (2008-2010 were estimated retrospectively using official population estimates as exposure time.The IRRa for pneumonia hospitalizations was 0.70 (95% confidence interval [CI]: 0.66, 0.75 for infants, and 0.92 (95% CI: 0.85, 0.99 for one year-olds. The IRRa for post-neonatal infant mortality was 0.56 (95% CI: 0.41, 0.77. In the population as a whole, ambulatory visits and hospitalizations for pneumonia, as well as pneumonia-related mortality and rates of bacterial meningitis were lower in the vaccine period.During the first five years of program implementation, reductions were observed in health facility visits for pneumonia in immunized age groups and infant mortality, which would be hard to achieve with any other single public health intervention. Future study is warranted to understand whether the lack of a booster dose (e.g., at 12 months may be responsible for the small reductions in pneumonia hospitalizations observed in one year-olds as compared to

  20. Commentary: An Introduction to Leadership Self-Assessment at the Society of Neurological Surgeons Post-Graduate Year 1 Boot Camp: Observations and Commentary.

    Science.gov (United States)

    Hunt, Matthew A; Heilman, Carl B; Shutran, Max; Wu, Julian K

    2017-03-01

    Recent trends in graduate medical education have emphasized the mastery of nontechnical skills, especially leadership, for neurosurgical trainees. Accordingly, we introduced leadership development and self-awareness training to interns attending the Society of Neurological Surgeons Post-Graduate Year 1 Boot Camp in the Northeast (New England/New York/New Jersey) region in 2015. Feedback about the session was collected from interns. While neurosurgical interns conveyed a desire to receive more information on improving their leadership skills, most indicated that guidance seemed to be lacking in this critical area. We discuss some of the professional development needs uncovered during this process. Copyright © 2017 by the Congress of Neurological Surgeons.

  1. Dimensional synthesis of six-bar Stephenson II linkage for fifteen precision points path generation

    Directory of Open Access Journals (Sweden)

    Khalid Nafees

    2016-09-01

    Full Text Available This paper presents the dimensional synthesis of a planar six-bar Stephenson II linkage having single degree of freedom with rotational constraints. The objective of the synthesis is to determine all the link lengths with their orientations of the linkage that is capable to follow the path specified by fifteen precision points. The analytical loop closure equations are formed using dyad and triad technique by means of complex number mathematics for path generation. These equations are solved simultaneously for fifteen displacement positions of coupler tracing point to determine various link lengths with their corresponding orientations. The displacement vector and coupler link motion are the prescribed parameters. The effectiveness of mechanism synthesis has been demonstrated on a numerical example. The solution of loop closure equations has been obtained using a MATLAB code. Finally, the determined link lengths with their orientations have been verified using SAM software.

  2. Sociophysics an introduction

    CERN Document Server

    Sen, Parongama

    2014-01-01

    This book discusses the study and analysis of the physical aspects of social systems and models, inspired by the analogy with familiar models of physical systems and possible applications of statistical physics tools. Unlike the traditional analysis of the physics of macroscopic many-body or condensed matter systems, which is now an established and mature subject, the upsurge in the physical analysis and modelling of social systems, which are clearly many-body dynamical systems, is a recent phenomenon. Though the major developments in sociophysics have taken place only recently, the earliest attempts of proposing "Social Physics" as a discipline are more than one and a half centuries old. Various developments in the mainstream physics of condensed matter systems have inspired and induced the recent growth of sociophysical analysis and models. In spite of the tremendous efforts of many scientists in recent years, the subject is still in its infancy and major challenges are yet to be taken up. An introduction t...

  3. Introduction to variance estimation

    CERN Document Server

    Wolter, Kirk M

    2007-01-01

    We live in the information age. Statistical surveys are used every day to determine or evaluate public policy and to make important business decisions. Correct methods for computing the precision of the survey data and for making inferences to the target population are absolutely essential to sound decision making. Now in its second edition, Introduction to Variance Estimation has for more than twenty years provided the definitive account of the theory and methods for correct precision calculations and inference, including examples of modern, complex surveys in which the methods have been used successfully. The book provides instruction on the methods that are vital to data-driven decision making in business, government, and academe. It will appeal to survey statisticians and other scientists engaged in the planning and conduct of survey research, and to those analyzing survey data and charged with extracting compelling information from such data. It will appeal to graduate students and university faculty who...

  4. Introduction to thermoelectricity

    CERN Document Server

    Goldsmid, H Julian

    2016-01-01

    This book is a comprehensive introduction to all aspects of thermoelectric energy conversion. It covers both theory and practice. The book is timely as it refers to the many improvements that have come about in the last few years through the use of nanostructures. The concept of semiconductor thermoelements led to major advances during the second half of the twentieth century, making Peltier refrigeration a widely used technique. The latest materials herald thermoelectric generation as the preferred technique for exploiting low-grade heat. The book shows how progress has been made by increasing the thermal resistivity of the lattice until it is almost as large as it is for glass. It points the way towards the attainment of similar improvements in the electronic parameters. It does not neglect practical considerations, such as the desirability of making thermocouples from inexpensive and environmentally acceptable materials. The second edition was extended to also include recent advances in thermoelectric ener...

  5. Introduction to thermoelectricity

    CERN Document Server

    Goldsmid, H Julian

    2010-01-01

    Introduction to Thermoelectricity is the latest work by Professor Julian Goldsmid drawing on his 55 years experience in the field. The theory of the thermoelectric and related phenomena is presented in sufficient detail to enable researchers to understand their observations and develop improved thermoelectric materials. The methods for the selection of materials and their improvement are discussed. Thermoelectric materials for use in refrigeration and electrical generation are reviewed. Experimental techniques for the measurement of properties and for the production of thermoelements are described. Special emphasis is placed on nanotechnology which promises to yield great improvements in the efficiency of thermoelectric devices. Chapters are also devoted to transverse thermoelectric effects and thermionic energy conversion, both techniques offering the promise of important applications in the future.

  6. Nasopharyngeal carriage of Streptococcus pneumoniae among HIV-infected and -uninfected children <5 years of age before introduction of pneumococcal conjugate vaccine in Mozambique.

    Directory of Open Access Journals (Sweden)

    Jennifer R Verani

    Full Text Available Nasopharyngeal carriage is a precursor for pneumococcal disease and can be useful for evaluating pneumococcal conjugate vaccine (PCV impact. We studied pre-PCV pneumococcal carriage among HIV-infected and -uninfected children in Mozambique. Between October 2012 and March 2013, we enrolled HIV-infected children age <5 years presenting for routine care at seven HIV clinics in 3 sites, including Maputo (urban-south, Nampula (urban-north, and Manhiça (rural-south. We also enrolled a random sample of HIV-uninfected children <5 years old from a demographic surveillance site in Manhiça. A single nasopharyngeal swab was obtained and cultured following enrichment in Todd Hewitt broth with yeast extract and rabbit serum. Pneumococcal isolates were serotyped by Quellung reaction and multiplex polymerase chain reaction. Factors associated with pneumococcal carriage were examined using logistic regression. Overall pneumococcal carriage prevalence was 80.5% (585/727, with similar prevalences among HIV-infected (81.5%, 339/416 and HIV-uninfected (79.1%, 246/311 children, and across age strata. Among HIV-infected, after adjusting for recent antibiotic use and hospitalization, there was no significant association between study site and colonization: Maputo (74.8%, 92/123, Nampula (83.7%, 82/98, Manhiça (84.6%, 165/195. Among HIV-uninfected, report of having been born to an HIV-infected mother was not associated with colonization. Among 601 pneumococcal isolates from 585 children, serotypes 19F (13.5%, 23F (13.1%, 6A (9.2%, 6B (6.2% and 19A (5.2% were most common. The proportion of serotypes included in the 10- and 13-valent vaccines was 44.9% and 61.7%, respectively, with no significant differences by HIV status or age group. Overall 36.9% (n = 268 of children were colonized with a PCV10 serotype and 49.7% (n = 361 with a PCV13 serotype. Pneumococcal carriage was common, with little variation by geographic region, age, or HIV status. PCV10 was introduced in

  7. Introduction to Special Issue: A Review of the International Classification of Functioning, Disability and Health and Physical Therapy over the Years.

    Science.gov (United States)

    Escorpizo, Reuben; Bemis-Dougherty, Anita

    2015-12-01

    The International Classification of Functioning, Disability and Health (ICF) of the World Health Organization was developed as a common framework to understand health and to describe the impact of health condition on functioning. The purpose of this paper is to summarize the literature on the use of the ICF in physical therapy practice and research. We performed a scoping-narrative review and searched for relevant English language articles from 2001 to 2012 in multiple databases that included MEDLINE, PsycINFO, PubMed and Physiotherapy Evidence Database. Our keywords for the search consisted of ['physical therapy' OR 'physiotherapy'] AND ['ICF']. All types of articles were considered. We found 268 articles; out of which, 79 were reviewed. The years with most publications were 2011 (n = 16), 2008 (n = 15) and 2010 and 2012 (both with n = 13). Publications mostly came from the United States with 27% of the articles. The journal Physical Therapy leads with almost a third of ICF-related physical therapy publications. The ICF has been mostly used in studies of musculoskeletal and neuromuscular conditions. We found a wide array of application of the ICF in research, clinical practice and teaching (classroom and clinical education). Emerging topics included using the ICF in resource allocation and prevention and wellness. The use of the ICF in physical therapy practice and research is promising and continues to evolve. With recent developments in ICF-based measurement and integration in assessment tools for use in the clinics, research and teaching, the need to show the added value of using the ICF in practice and research remains. Copyright © 2013 John Wiley & Sons, Ltd.

  8. Italy and Austria before and after study: second-hand smoke exposure in hospitality premises before and after 2 years from the introduction of the Italian smoking ban.

    Science.gov (United States)

    Gorini, G; Moshammer, H; Sbrogiò, L; Gasparrini, A; Nebot, M; Neuberger, M; Tamang, E; Lopez, M J; Galeone, D; Serrahima, E

    2008-08-01

    The aim of this paper was to compare nicotine concentration in 28 hospitality premises (HPs) in Florence and Belluno, Italy, where a smoking ban was introduced in 2005, and in 19 HPs in Vienna, Austria, where no anti-smoking law entered into force up to now. Airborne nicotine concentrations were measured in the same HPs in winter 2002 or 2004 (pre-ban measurements) and winter 2007 (post-ban measurements). In Florence and Belluno, medians decreased significantly (P hospitality workers of 11.81 and 14.67 per 10,000, respectively. Lifetime excess lung cancer mortality risks for bar and disco-pub workers were 10-20 times higher than that calculated for restaurant workers, both in Italy and Austria. In winter 2007, it dropped to 0.01 per 10,000 in Italy, whereas in Austria it remained at the same levels. The drop of second-hand smoke exposure indicates a substantial improvement in air quality in Italian HPs even after 2 years from the ban. The nation-wide smoking ban introduced in Italy on January 10, 2005, resulted in a drop in second-hand smoke exposure in hospitality premises, whereas in Austria, where there is no similar nation-wide smoking ban, the exposure to second-hand smoke in hospitality premises remains high. Given that second-hand smoke is considered a group 1 carcinogen according to the International Agency for Research on Cancer classification, the World Health Organization Framework Convention on Tobacco Control strongly recommends the implementation of nation-wide smoke-free policies in order to improve the indoor air quality of hospitality premises and workplaces. Results from our study strongly supports this recommendation.

  9. Anti-malarial prescribing practices in Sudan eight years after introduction of artemisinin-based combination therapies and implications for development of drug resistance.

    Science.gov (United States)

    Elmannan, Abeer Abuzeid Atta; Elmardi, Khalid Abdelmutalab; Idris, Yassir Ali; Spector, Jonathan M; Ali, Nahid Abdelgadir; Malik, Elfatih Mohamed

    2015-03-26

    The World Health Organization (WHO) recommends artemisinin-based combination therapies (ACTs) as first-line treatment for uncomplicated malaria. Sudan revised its malaria treatment policy accordingly in 2004. However, eight years after ACTs were introduced in Sudan the patterns of ACT prescribing practices among health care providers remain unclear. We systematically analyzed use of ACTs in a large number of primary health facilities and we discuss the public health implications of our findings. This cross-sectional study was based on WHO's guidance for investigating drug use in health facilities. Data were collected from 40 randomly selected primary health centers in five localities in Gezira State, Sudan. The primary outcome of the study was the proportion of patients who were adequately managed according to Sudan's recommended malaria treatment guidelines. Twelve drug-use indicators were used to assess key ACT prescribing practices. One thousand and two hundred patients diagnosed with uncomplicated malaria were recruited into the study. ACT was prescribed for 88.6%patients and artemether injections were (incorrectly) prescribed in 9.5% of cases. Only 40.9% of patients in the study were correctly diagnosed and 26.9% were adequately managed according to the nationally recommended treatment guidelines. Incorrect prescribing activities included failure to use generic medicine names (88.2%), incorrect dosage (27.7%), and unexplained antibiotic co-prescription (24.2%). Dispensing practices were also poor, with labeling practices inadequate (97.1%) and insufficient information given to patients about their prescribed treatment (50.5%). Irrational malaria treatment practices are common in Sudan. This has important public health implications since failure to adhere to nationally recommended guidelines could play a role in the future development of drug resistance. As such, identifying ways to improve the anti-malarial prescribing practices of heath workers in Sudan may

  10. An introduction to quantum mechanics

    International Nuclear Information System (INIS)

    Hannabuss, K.C.

    1988-06-01

    The notes were prepared as an introduction to quantum theory for final year undergraduate students. Following an introduction which briefly recounts the development of quantum theory there are four chapters which cover wave mechanics, simple quantum mechanical systems, the mathematical structure of quantum theory and the Uncertainty Principle. The first appendix covers the Hamiltonian mechanics needed for the course. All the chapters and this appendix have problems set at the end which can be worked through. Appendix B mentions paradoxes and experimental tests of quantum theory. (author)

  11. Introduction to applied algebraic systems

    CERN Document Server

    Reilly, Norman R

    2009-01-01

    This upper-level undergraduate textbook provides a modern view of algebra with an eye to new applications that have arisen in recent years. A rigorous introduction to basic number theory, rings, fields, polynomial theory, groups, algebraic geometry and elliptic curves prepares students for exploring their practical applications related to storing, securing, retrieving and communicating information in the electronic world. It will serve as a textbook for an undergraduate course in algebra with a strong emphasis on applications. The book offers a brief introduction to elementary number theory as

  12. An introduction to fire dynamics

    CERN Document Server

    Drysdale, Dougal

    2011-01-01

    "Drysdale's book is by far the most comprehensive - everyone in the office has a copy...now including me. It holds just about everything you need to know about fire science."(Review of An Introduction to Fire Dynamics, 2nd Edition) After 25 years as a bestseller, Dougal Drysdale's classic introduction has been brought up-to-date and expanded to incorporate the latest research and experimental data.  Homework problems are included, with solutions, and others are available on the accompanying website at www.wiley.com/go/drysdale. Essential reading for all involved in the field from undergraduate

  13. Staff perceptions of addressing lifestyle in primary health care: a qualitative evaluation 2 years after the introduction of a lifestyle intervention tool.

    Science.gov (United States)

    Carlfjord, Siw; Lindberg, Malou; Andersson, Agneta

    2012-10-10

    Preventive services and health promotion in terms of lifestyle counselling provided through primary health care (PHC) has the potential to reduce morbidity and mortality in the population. Health professionals in general are positive about and willing to develop a health-promoting and/or preventive role. A number of obstacles hindering PHC staff from addressing lifestyle issues have been identified, and one facilitator is the use of modern technology. When a computer-based tool for lifestyle intervention (CLT) was introduced at a number of PHC units in Sweden, this provided an opportunity to study staff perspectives on the subject. The aim of this study was to explore PHC staff's perceptions of handling lifestyle issues, including the consultation situation as well as the perceived usefulness of the CLT. A qualitative study was conducted after the CLT had been in operation for 2 years. Six focus group interviews, one at each participating unit, including a total of 30 staff members with different professions participated. The interviews were designed to capture perceptions of addressing lifestyle issues, and of using the CLT. Interview data were analysed using manifest content analysis. Two main themes emerged from the interviews: a challenging task and confidence in handling lifestyle issues. The first theme covered the categories responsibilities and emotions, and the second theme covered the categories first contact, existing tools, and role of the CLT. Staff at the units showed commitment to health promotion/prevention, and saw that patients, caregivers, managers and politicians all have responsibilities regarding the issue. They expressed confidence in handling lifestyle-related conditions, but to a lesser extent had routines for general screening of lifestyle habits, and found addressing alcohol the most problematic issue. The CLT, intended to facilitate screening, was viewed as a complement, but was not considered an important tool for health promotion

  14. Staff perceptions of addressing lifestyle in primary health care: a qualitative evaluation 2 years after the introduction of a lifestyle intervention tool

    Directory of Open Access Journals (Sweden)

    Carlfjord Siw

    2012-10-01

    Full Text Available Abstract Background Preventive services and health promotion in terms of lifestyle counselling provided through primary health care (PHC has the potential to reduce morbidity and mortality in the population. Health professionals in general are positive about and willing to develop a health-promoting and/or preventive role. A number of obstacles hindering PHC staff from addressing lifestyle issues have been identified, and one facilitator is the use of modern technology. When a computer-based tool for lifestyle intervention (CLT was introduced at a number of PHC units in Sweden, this provided an opportunity to study staff perspectives on the subject. The aim of this study was to explore PHC staff’s perceptions of handling lifestyle issues, including the consultation situation as well as the perceived usefulness of the CLT. Methods A qualitative study was conducted after the CLT had been in operation for 2 years. Six focus group interviews, one at each participating unit, including a total of 30 staff members with different professions participated. The interviews were designed to capture perceptions of addressing lifestyle issues, and of using the CLT. Interview data were analysed using manifest content analysis. Results Two main themes emerged from the interviews: a challenging task and confidence in handling lifestyle issues. The first theme covered the categories responsibilities and emotions, and the second theme covered the categories first contact, existing tools, and role of the CLT. Staff at the units showed commitment to health promotion/prevention, and saw that patients, caregivers, managers and politicians all have responsibilities regarding the issue. They expressed confidence in handling lifestyle-related conditions, but to a lesser extent had routines for general screening of lifestyle habits, and found addressing alcohol the most problematic issue. The CLT, intended to facilitate screening, was viewed as a complement, but was not

  15. Einführung und Evaluierung des praktischen Jahres an der Tierärztlichen Hochschule Hannover [Introduction and evaluation of final-year practice-oriented education at the University of Veterinary Medicine in Hanover, Germany

    Directory of Open Access Journals (Sweden)

    Wagels, Rolf

    2008-11-01

    Full Text Available [english] The introduction of a year of practice-oriented education should provide students of the University of Veterinary Medicine in Hanover greater integration in the clinical and scientific setting in order to gain “real-life” experience for their later profession before the end of their studies. This year replaces the old 9th and 10th semesters and builds a bridge between the well-organized and structured studies and the later profession. It includes internships outside the university in private practice, private clinics, slaughterhouses, etc., and a practical semester that can be completely at any time of the year in clinics and other institutes of the university. The online evaluation of this year has been positive. [german] Mit der Einführung des praktischen Jahres sollen die Studierenden der Tierärztlichen Hochschule Hannover (TiHo stärker in den klinischen und wissenschaftlichen Alltag eingebunden werden, um schon vor Ende des Studiums praxisnahe Erfahrungen zu sammeln. Das praktische Jahr ersetzt das bisherige 9. und 10. Semester und bildet so die Überleitung zwischen dem eng organisierten Studium und der anschließenden beruflichen Laufbahn. Es beinhaltet die Praktika außerhalb der TiHo in Tierarztpraxen, Privatkliniken, Schlachthöfen, etc. und ein internes praktisches Semester, welches das gesamte Jahr über in den Einrichtungen der TiHo abgeleistet werden kann. Die Online-Evaluierung dieses Jahres verlief positiv.

  16. WE-B-210-01: Introduction

    International Nuclear Information System (INIS)

    Holland, M.

    2015-01-01

    In the last fifteen years, the introduction of plane or diverging wave transmissions rather than line by line scanning focused beams has broken the conventional barriers of ultrasound imaging. By using such large field of view transmissions, the frame rate reaches the theoretical limit of physics dictated by the ultrasound speed and an ultrasonic map can be provided typically in tens of micro-seconds (several thousands of frames per second). Interestingly, this leap in frame rate is not only a technological breakthrough but it permits the advent of completely new ultrasound imaging modes, including shear wave elastography, electromechanical wave imaging, ultrafast doppler, ultrafast contrast imaging, and even functional ultrasound imaging of brain activity (fUltrasound) introducing Ultrasound as an emerging full-fledged neuroimaging modality. At ultrafast frame rates, it becomes possible to track in real time the transient vibrations – known as shear waves – propagating through organs. Such “human body seismology” provides quantitative maps of local tissue stiffness whose added value for diagnosis has been recently demonstrated in many fields of radiology (breast, prostate and liver cancer, cardiovascular imaging, …). Today, Supersonic Imagine company is commercializing the first clinical ultrafast ultrasound scanner, Aixplorer with real time Shear Wave Elastography. This is the first example of an ultrafast Ultrasound approach surpassing the research phase and now widely spread in the clinical medical ultrasound community with an installed base of more than 1000 Aixplorer systems in 54 countries worldwide. For blood flow imaging, ultrafast Doppler permits high-precision characterization of complex vascular and cardiac flows. It also gives ultrasound the ability to detect very subtle blood flow in very small vessels. In the brain, such ultrasensitive Doppler paves the way for fUltrasound (functional ultrasound imaging) of brain activity with unprecedented

  17. WE-B-210-01: Introduction

    Energy Technology Data Exchange (ETDEWEB)

    Holland, M. [Indiana University-School of Medicine (United States)

    2015-06-15

    In the last fifteen years, the introduction of plane or diverging wave transmissions rather than line by line scanning focused beams has broken the conventional barriers of ultrasound imaging. By using such large field of view transmissions, the frame rate reaches the theoretical limit of physics dictated by the ultrasound speed and an ultrasonic map can be provided typically in tens of micro-seconds (several thousands of frames per second). Interestingly, this leap in frame rate is not only a technological breakthrough but it permits the advent of completely new ultrasound imaging modes, including shear wave elastography, electromechanical wave imaging, ultrafast doppler, ultrafast contrast imaging, and even functional ultrasound imaging of brain activity (fUltrasound) introducing Ultrasound as an emerging full-fledged neuroimaging modality. At ultrafast frame rates, it becomes possible to track in real time the transient vibrations – known as shear waves – propagating through organs. Such “human body seismology” provides quantitative maps of local tissue stiffness whose added value for diagnosis has been recently demonstrated in many fields of radiology (breast, prostate and liver cancer, cardiovascular imaging, …). Today, Supersonic Imagine company is commercializing the first clinical ultrafast ultrasound scanner, Aixplorer with real time Shear Wave Elastography. This is the first example of an ultrafast Ultrasound approach surpassing the research phase and now widely spread in the clinical medical ultrasound community with an installed base of more than 1000 Aixplorer systems in 54 countries worldwide. For blood flow imaging, ultrafast Doppler permits high-precision characterization of complex vascular and cardiac flows. It also gives ultrasound the ability to detect very subtle blood flow in very small vessels. In the brain, such ultrasensitive Doppler paves the way for fUltrasound (functional ultrasound imaging) of brain activity with unprecedented

  18. Introduction to graph theory

    CERN Document Server

    Trudeau, Richard J

    1994-01-01

    Preface1. Pure Mathematics Introduction; Euclidean Geometry as Pure Mathematics; Games; Why Study Pure Mathematics?; What's Coming; Suggested Reading2. Graphs Introduction; Sets; Paradox; Graphs; Graph diagrams; Cautions; Common Graphs; Discovery; Complements and Subgraphs; Isomorphism; Recognizing Isomorphic Graphs; Semantics The Number of Graphs Having a Given nu; Exercises; Suggested Reading3. Planar Graphs Introduction; UG, K subscript 5, and the Jordan Curve Theorem; Are there More Nonplanar Graphs?; Expansions; Kuratowski's Theorem; Determining Whether a Graph is Planar or

  19. Bayesian Networks An Introduction

    CERN Document Server

    Koski, Timo

    2009-01-01

    Bayesian Networks: An Introduction provides a self-contained introduction to the theory and applications of Bayesian networks, a topic of interest and importance for statisticians, computer scientists and those involved in modelling complex data sets. The material has been extensively tested in classroom teaching and assumes a basic knowledge of probability, statistics and mathematics. All notions are carefully explained and feature exercises throughout. Features include:.: An introduction to Dirichlet Distribution, Exponential Families and their applications.; A detailed description of learni

  20. Introduction to clinical nutrition

    National Research Council Canada - National Science Library

    Sardesai, Vishwanath M

    2012-01-01

    .... Introduction to Clinical Nutrition, Third edition discusses the physiologic and metabolic interrelationships of all nutrients and their roles in health maintenance and the prevention of various...

  1. Developmental profiles on the basis of the FTF (Five to Fifteen) questionnaire

    DEFF Research Database (Denmark)

    Trillingsgaard, Anegen; Damm, Dorte; Sommer, Søren

    2004-01-01

    The Five to Fifteen parent questionnaire (FTF) was developed to offer a neuropsychological dimension to the assessment of children with Attention Deficit/Hyperactivity Disorder and other child psychiatric disorders. The domains included in the FTF were motor skills, executive functions, perception......, memory, language, social skills and learning, in addition to a domain for emotional and behavioural problems. The aim of the present study was to test the clinical validity and utility of the FTF with a main focus on discriminant and criterion validity. The clinical sample consisted of 155 clinically...

  2. Intermedia transfer factors for fifteen toxic pollutants released to air basins in California

    Energy Technology Data Exchange (ETDEWEB)

    McKone, T.E.; Daniels, J.I. [Lawrence Livermore National Lab., CA (United States); Chiao, F.F.; Hsieh, D.P.H. [Univ. of California, Davis, CA (United States)

    1993-10-01

    This report provides a summary definition of the intermedia-transfer factors (ITFs). Methods are discussed for estimating these parameters in the absence of measured values, and the estimation errors inherent in these estimation methods are considered. A detailed summary is provided of measured and estimated ITF values for fifteen air contaminants. They include: 1,3 butadiene; cadmium; cellosolve; cellosolve acetate; chloroform; di-2-ethylhexylphthalate; 1,4-dioxame; hexachlorobenzene; inorganic arsenic; inorganic lead; nickel; tetrachloroethylene; toluene; toluene-2,4-diisocyanate; and 1,3-xylene. Recommendations are made regarding the expected value and variance in these values for use in exposure models.

  3. The Nordic Five to Fifteen questionnaire could provide the basis for a common neurological disability variable

    DEFF Research Database (Denmark)

    Illum, Niels Ove; Gradel, Kim Oren

    2014-01-01

    AIMS: Assessing disabilities in children is essential and Danish parents provide increasingly important feedback on how their child's disability affects daily living. The Nordic Five to Fifteen (FTF) parent questionnaire is widely used in Nordic countries to detect atypical or delayed development...... with children with neurological disabilities, and the Rasch scale analysis results indicate that it could form the analytical basis for developing a common disability variable....... in children. Our study evaluated its internal validity and whether it could be used to generate a common disability variable across childhood neurological disorders and severities. METHODS: The 28-statement FTF questionnaire was completed by the parents of children with spina bifida, muscular disorders...

  4. Introduction to Part 3

    DEFF Research Database (Denmark)

    Petersen, Nils Holger

    2015-01-01

    A brief contextualising discussion of Western Music History and its relations to Theological Aesthetical Thought since Carolingian Times as an introduction to 3 music articles in Part 3 of the volume.......A brief contextualising discussion of Western Music History and its relations to Theological Aesthetical Thought since Carolingian Times as an introduction to 3 music articles in Part 3 of the volume....

  5. Introduction to surveillance studies

    CERN Document Server

    Petersen, JK

    2012-01-01

    Introduction & OverviewIntroduction Brief History of Surveillance Technologies & TechniquesOptical SurveillanceAerial Surveillance Audio Surveillance Radio-Wave SurveillanceGlobal Positioning Systems Sensors Computers & the Internet Data Cards Biochemical Surveillance Animal Surveillance Biometrics Genetics Practical ConsiderationsPrevalence of Surveillance Effectiveness of Surveillance Freedom & Privacy IssuesConstitutional Freedoms Privacy Safeguards & Intrusions ResourcesReferences Glossary Index

  6. Environmental Psychology: An Introduction

    NARCIS (Netherlands)

    Steg, L.; Berg, van den A.E.; Groot, de J.I.M.

    2012-01-01

    Environmental Psychology: An Introduction offers a research-based introduction to the psychological relationship between humans and their built and natural environments and discusses how sustainable environments can be created to the benefit of both people and nature •Explores the environment's

  7. Atmospheric pollution. Introduction; Pollution atmospherique. Introduction

    Energy Technology Data Exchange (ETDEWEB)

    Elichegaray, Ch. [Agence de l' Environnement et de la Maitrise de l' Energie, 75 - Paris (France)

    2006-07-15

    This article is a general introduction to air pollution. It focusses on air quality problems at the local and regional scale: 1 - atmospheric environment and determining factors of its quality; 2 - French situation; 3 - local scale impacts: health hazards; 4 - regional scale impacts: risks for health and ecosystems (acid rains, photochemical pollution); 5 - management of the atmospheric environment (national scale, international scale: monitoring of air quality and role of the French agency of environment and energy mastery - Ademe). (J.S.)

  8. Introduction to industrial radiography

    International Nuclear Information System (INIS)

    Abdul Nassir Ibrahim; Azali Muhammad; Ab. Razak Hamzah; Abd. Aziz Mohamed; Mohamad Pauzi Ismail

    2008-01-01

    For the first topic in this book, more on introduction to nondestructive testing, also a little bit on another technique such as magnetic testing, liquid penetrated, ultrasonic testing and others. This book mentions more on radiographic testing and for that, more details on this topic such as history, definition and devices that use in this technique. This radiography testing firstly started with the discovering of x-ray by Wilhelm Roentgen (1895). So, on 1913, David Coolidge successfully invented and developed x-ray tube that could made x-ray more intensified and produced highly penetration forces. Radiography in Malaysia firstly started two years after the discovery made by Wilhelm Roentgen when one hospital here used the x-ray machine for medical purposes. Besides using x-ray, radiography also used gamma rays, and for these purpose, they used Co-60 and Ir-192. Now, more company based on NDT established to provide a service on inspection pipe and others. For filled these requirement, radiographer must take an exam to make them expert and trained well to work in this field. There is no advantage using this technique or other technique. So that's why this book was published to make people understand what is radiographic testing truly.

  9. Introduction - Chadwick discovers the neutron

    International Nuclear Information System (INIS)

    Hendry, J.

    1984-01-01

    The background to Chadwick's discovery in 1932 of the neutron predicted by Rutherford is chronicled. In the same year Cockcroft and Walton split the atom, and the story of this event is told. 1932 also saw the demonstration by Blackett and Occhialini of the existence of the positron. These important contributions to nuclear physics were all made at the Cavendish Laboratory in Cambridge. Photographs, extracts from experimental notebooks and circuit diagrams illustrate this introduction. (UK)

  10. An introduction to computational micromechanics

    CERN Document Server

    Zohdi, Tarek I; Zohdi, Tarek I

    2004-01-01

    In this, its second corrected printing, Zohdi and Wriggers' illuminating text presents a comprehensive introduction to the subject. The authors include in their scope basic homogenization theory, microstructural optimization and multifield analysis of heterogeneous materials. This volume is ideal for researchers and engineers, and can be used in a first-year course for graduate students with an interest in the computational micromechanical analysis of new materials.

  11. An introduction to statistical parametric speech synthesis

    Indian Academy of Sciences (India)

    - like models, has become competitive with established concatenative techniques over the last few years. This paper offers a non-mathematical introduction to this method of speech synthesis. It is intended to be complementary to the wide ...

  12. Introduction to renewable energy

    CERN Document Server

    Nelson, Vaughn C

    2011-01-01

    IntroductionEnergy and SocietyTypes of EnergyRenewable EnergyAdvantages/DisadvantagesEconomicsGlobal WarmingOrder of Magnitude EstimatesGrowth (Exponential)SolutionsEnergyIntroductionDefinition of Energy and PowerHeatThermodynamicsEnergy Dilemma in Light of the Laws of ThermodynamicsUse of Fossil FuelsNuclearFinite ResourceSummarySunSolar PowerElectromagnetic SpectrumEnergy Balance of the EarthEarth-Sun MotionInsolationSolar ResourceGreenhouse EffectHeat Transfer and StorageIntroductionConductionConvectionRadiationThermal MassSeasonal Heating or CoolingThermal ComfortSolar Heating and CoolingB

  13. Introduction to quantum mechanics

    CERN Document Server

    Phillips, A C

    2003-01-01

    Introduction to Quantum Mechanics is an introduction to the power and elegance of quantum mechanics. Assuming little in the way of prior knowledge, quantum concepts are carefully and precisely presented, and explored through numerous applications and problems. Some of the more challenging aspects that are essential for a modern appreciation of the subject have been included, but are introduced and developed in the simplest way possible.Undergraduates taking a first course on quantum mechanics will find this text an invaluable introduction to the field and help prepare them for more adv

  14. Introduction to neural networks

    CERN Document Server

    James, Frederick E

    1994-02-02

    1. Introduction and overview of Artificial Neural Networks. 2,3. The Feed-forward Network as an inverse Problem, and results on the computational complexity of network training. 4.Physics applications of neural networks.

  15. MOOC Introduction to Dutch

    NARCIS (Netherlands)

    den Hollander, Franciscus; Piersma, Kristien

    Interview met Margriet Hidding, Birgit Lijmbach en Jeroen van Engen, medewerkers van het Talencentrum en de makers van de Massive Open Online Course (MOOC) Introduction to Dutch over het grote succes van deze cursus

  16. Introduction to Biophotonics

    Science.gov (United States)

    Prasad, Paras N.

    2003-04-01

    Paras Prasad's text provides a basic knowledge of a broad range of topics so that individuals in all disciplines can rapidly acquire the minimal necessary background for research and development in biophotonics. Introduction to Biophotonics serves as both a textbook for education and training as well as a reference book that aids research and development of those areas integrating light, photonics, and biological systems. Each chapter contains a topic introduction, a review of key data, and description of future directions for technical innovation. Introduction to Biophotonics covers the basic principles of Optics Optical spectroscopy Microscopy Each section also includes illustrated examples and review questions to test and advance the reader's knowledge. Sections on biosensors and chemosensors, important tools for combating biological and chemical terrorism, will be of particular interest to professionals in toxicology and other environmental disciplines. Introduction to Biophotonics proves a valuable reference for graduate students and researchers in engineering, chemistry, and the life sciences.

  17. Introduction to graph theory

    CERN Document Server

    Wilson, Robin J

    1985-01-01

    Graph Theory has recently emerged as a subject in its own right, as well as being an important mathematical tool in such diverse subjects as operational research, chemistry, sociology and genetics. This book provides a comprehensive introduction to the subject.

  18. Introduction to Event Data

    OpenAIRE

    Fenner, Martin

    2017-01-01

    Introduction to Event Data” presented by Martin Fenner (DataCite) at the Joint Global Infrastructure Conference co-hosted by Crossref, DataCite, and ORCID at the Korea Chamber of Commerce & Industry on 15 June 2017.

  19. Introduction to numerical analysis

    CERN Document Server

    Hildebrand, F B

    1987-01-01

    Well-known, respected introduction, updated to integrate concepts and procedures associated with computers. Computation, approximation, interpolation, numerical differentiation and integration, smoothing of data, other topics in lucid presentation. Includes 150 additional problems in this edition. Bibliography.

  20. Complex Systems: An Introduction

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 14; Issue 9. Complex Systems: An Introduction - Anthropic Principle, Terrestrial Complexity, Complex Materials. V K Wadhawan. General Article Volume 14 Issue 9 September 2009 pp 894-906 ...

  1. Dissociative chemisorption of methane on Ni(111) using a chemically accurate fifteen dimensional potential energy surface.

    Science.gov (United States)

    Zhou, Xueyao; Nattino, Francesco; Zhang, Yaolong; Chen, Jun; Kroes, Geert-Jan; Guo, Hua; Jiang, Bin

    2017-11-22

    A fifteen-dimensional global potential energy surface for the dissociative chemisorption of methane on the rigid Ni(111) surface is developed by a high fidelity fit of ∼200 000 DFT energy points computed using a specific reaction parameter density functional designed to reproduce experimental data. The permutation symmetry and surface periodicity are rigorously enforced using the permutation invariant polynomial-neural network approach. The fitting accuracy of the potential energy surface is thoroughly investigated by examining both static and dynamical attributes of CHD 3 dissociation on the frozen surface. This potential energy surface is expected to be chemically accurate as after correction for surface temperature effects it reproduces the measured initial sticking probabilities of CHD 3 on Ni(111) for various incidence conditions.

  2. Introduction to abstract algebra

    CERN Document Server

    Smith, Jonathan D H

    2008-01-01

    Taking a slightly different approach from similar texts, Introduction to Abstract Algebra presents abstract algebra as the main tool underlying discrete mathematics and the digital world. It helps students fully understand groups, rings, semigroups, and monoids by rigorously building concepts from first principles. A Quick Introduction to Algebra The first three chapters of the book show how functional composition, cycle notation for permutations, and matrix notation for linear functions provide techniques for practical computation. The author also uses equivalence relations to introduc

  3. Introduction to particle accelerators

    CERN Document Server

    Wilson, Edmund J N

    1995-01-01

    2/10 Mathematical Introduction : matrices ; 3/10 Mathematical Introduction : differential equations ; 4/10 Phase stability and focusing principles ; 6/10 Lattices and such ; 10/10 More transverse beam dynamics ; 11/10 Closed orbit and gradient errors. 13/10 RF bunches, buckets, dispertion and transiton ; 16/10 Magnets, multipoles and resonances ; 17/10 Electron dynamics ; 18/10 Instabilities ; 19/10 The future.

  4. General introduction to glucosinolates

    DEFF Research Database (Denmark)

    Halkier, Barbara Ann

    2016-01-01

    will be presented a general introduction to glucosinolates ranging from the evolution of glucosinolates to the many roles glucosinolates have for humans as well as an overview of the current knowledge on the orchestration of the glucosinolate biosynthetic pathway. The latter includes an introduction to the genes...... to the plasma membrane. Examples of how the knowledge gained from basic research has been translated into applied glucosinolate research through pathway and transport engineering will be presented....

  5. Stochastic processes an introduction

    CERN Document Server

    Jones, Peter Watts

    2009-01-01

    Some Background on ProbabilityIntroduction Probability Conditional probability and independence Discrete random variables Continuous random variables Mean and variance Some standard discrete probability distributions Some standard continuous probability distributions Generating functions Conditional expectationSome Gambling ProblemsGambler's ruin Probability of ruin Some numerical simulations Duration of the game Some variations of gambler's ruinRandom WalksIntroduction Unrestricted random walks The probability distribution after n steps First returns of the symmetric random walkMarkov ChainsS

  6. Introduction to remote sensing

    CERN Document Server

    Cracknell, Arthur P

    2007-01-01

    Addressing the need for updated information in remote sensing, Introduction to Remote Sensing, Second Edition provides a full and authoritative introduction for scientists who need to know the scope, potential, and limitations in the field. The authors discuss the physical principles of common remote sensing systems and examine the processing, interpretation, and applications of data. This new edition features updated and expanded material, including greater coverage of applications from across earth, environmental, atmospheric, and oceanographic sciences. Illustrated with remotely sensed colo

  7. Assessment of the dining environment on and near the campuses of fifteen post-secondary institutions.

    Science.gov (United States)

    Horacek, Tanya M; Erdman, Maria B; Byrd-Bredbenner, Carol; Carey, Gale; Colby, Sarah M; Greene, Geoffrey W; Guo, Wen; Kattelmann, Kendra K; Olfert, Melissa; Walsh, Jennifer; White, Adrienne B

    2013-07-01

    The present study evaluated the restaurant and dining venues on and near post-secondary campuses varying in institution size. The Nutrition Environment Measures Survey for Restaurants (NEMS-R) was modified to evaluate restaurants as fast food, sit down and fast casual; and campus dining venues as dining halls, student unions and snack bar/cafe´s. ANOVA with post hoc Tukey’s B and T tests were used to distinguish differences between dining venues and associated institutions by size. The study was conducted at fifteen US post-secondary institutions, 2009–2011. Data presented are from a sample of 175 restaurants and sixty-eight on-campus dining venues. There were minimal differences in dining halls by institution size, although medium-sized institutions as compared with small-sized institutions offered significantly more healthful side dish/salad bar items. Dining halls scored significantly higher than student unions or snack bar/cafe´s on healthful entre´es, side dish/salad bar and beverages offerings, but they also had the most barriers to healthful dietary habits (i.e. all-you-can-eat). No differences were found by restaurant type for NEMS-R scores for total restaurant dining environment or healthful entre´es and barriers. Snack bars had more healthful side dishes (P50?002) and fast-food restaurants had the highest level of facilitators (i.e. nutrition information; P50?002). Based on this evaluation in fifteen institutions, the full campus dining environment provides limited support for healthy eating and obesity prevention. The quality of campus dining environments can be improved via healthful offerings, providing nutrition information and other supports to facilitate healthy eating and prevent unwanted weight gain.

  8. ONE HUNDRED YEARS OF MILES’ OPERATION- WHAT HAS CHANGED?

    Directory of Open Access Journals (Sweden)

    Vanja Pecić

    2008-12-01

    Full Text Available Lisfranc was probably the first to excise the rectum for cancer. He performed operation using perineal approach in 1826. This operation came into common use fifty years later. Czerny did the first combined abdominoperineal resection in attempt to finish excision he could not complete from below. Some fifteen years later Ernest Miles described the planned, one stage abdominoperineal resection.Miles name has become a synonym for this combined procedure, creating a radical change in the philosophy of resection and en bloc lymphadenectomy.In the beginning of twenty-century abdominoperineal resection became golden standard in the treatment of rectal cancer. Reconstructive operations, introduction of stapling devices and better understanding of potential tumor spread, reduced indications for Miles operation.Surgical treatment of rectal cancer made progress in the past 100 years. Miles was the first in line. Without his theory of perirectal lymphatic spread recurrence rate would be still as high as 95%.

  9. Introduction to AC machine design

    CERN Document Server

    Lipo, Thomas A

    2018-01-01

    AC electrical machine design is a key skill set for developing competitive electric motors and generators for applications in industry, aerospace, and defense. This book presents a thorough treatment of AC machine design, starting from basic electromagnetic principles and continuing through the various design aspects of an induction machine. Introduction to AC Machine Design includes one chapter each on the design of permanent magnet machines, synchronous machines, and thermal design. It also offers a basic treatment of the use of finite elements to compute the magnetic field within a machine without interfering with the initial comprehension of the core subject matter. Based on the author's notes, as well as after years of classroom instruction, Introduction to AC Machine Design: * Brings to light more advanced principles of machine design--not just the basic principles of AC and DC machine behavior * Introduces electrical machine design to neophytes while also being a resource for experienced designers * ...

  10. Complexity a very short introduction

    CERN Document Server

    Holland, John H

    2014-01-01

    The importance of complexity is well-captured by Hawking's comment: "Complexity is the science of the 21st century". From the movement of flocks of birds to the Internet, environmental sustainability, and market regulation, the study and understanding of complex non-linear systems has become highly influential over the last 30 years. In this Very Short Introduction, one of the leading figures in the field, John Holland, introduces the key elements and conceptual framework of complexity. From complex physical systems such as fluid flow and the difficulties of predicting weather, to complex adaptive systems such as the highly diverse and interdependent ecosystems of rainforests, he combines simple, well-known examples - Adam Smith's pin factory, Darwin's comet orchid, and Simon's 'watchmaker' - with an account of the approaches, involving agents and urn models, taken by complexity theory. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost eve...

  11. Fifteen-year follow-up of a patient with beta thalassaemia and extramedullary haematopoietic tissue compressing the spinal cord

    Energy Technology Data Exchange (ETDEWEB)

    Niggemann, P.; Krings, T.; Thron, A. [Dept. of Neuroradiology, RWTH-Aachen Hosital (Germany); Hans, F. [Dept. of Neurosurgery, RWTH Aachen Hospital (Germany); 1

    2005-04-01

    A long-term follow-up of a patient with beta thalassaemia with intra- and extraspinal extramedullary haematopoietic tissue compressing the spinal cord is presented. Extramedullary haematopoietic nodules are a rare cause of spinal cord compression and should be included in the differential diagnosis, especially in patients from Mediterranean countries. Treatment with radiation therapy solely failed, giving rise to the need of surgical intervention. Surgical decompression of the spine and the removal of the culprit lesion compressing the spine were performed. Postinterventional radiation therapy was applied to the spine. A relapse had to be treated again by surgical means combined with postinterventional radiation therapy. A complete relief of the symptoms and control of the lesion could be obtained.

  12. Fifteen-year follow-up of a patient with beta thalassaemia and extramedullary haematopoietic tissue compressing the spinal cord

    International Nuclear Information System (INIS)

    Niggemann, P.; Krings, T.; Thron, A.; Hans, F.

    2005-01-01

    A long-term follow-up of a patient with beta thalassaemia with intra- and extraspinal extramedullary haematopoietic tissue compressing the spinal cord is presented. Extramedullary haematopoietic nodules are a rare cause of spinal cord compression and should be included in the differential diagnosis, especially in patients from Mediterranean countries. Treatment with radiation therapy solely failed, giving rise to the need of surgical intervention. Surgical decompression of the spine and the removal of the culprit lesion compressing the spine were performed. Postinterventional radiation therapy was applied to the spine. A relapse had to be treated again by surgical means combined with postinterventional radiation therapy. A complete relief of the symptoms and control of the lesion could be obtained

  13. One the way to European Union: changes in the Czech education system during the last fifteen years

    OpenAIRE

    Milada Rubusicová

    2004-01-01

    The aim of the present paper is to describe the changes in the educationalsystem in the Czech Republic that have taken place from the beginning of the 1990’s up to the present. The first part includes a brief characterisation of the initial situation typical of the socialist model of education and a specification ofthose areas that were viewed sceptically or critically after the „velvet revolution»in 1989, and that have been identified as areas where a change is desirable. Next part of the pa...

  14. Update on best available options in obstetrics anaesthesia: perinatal outcomes, side effects and maternal satisfaction. Fifteen years systematic literature review.

    Science.gov (United States)

    Gizzo, Salvatore; Noventa, Marco; Fagherazzi, Simone; Lamparelli, Laura; Ancona, Emanuele; Di Gangi, Stefania; Saccardi, Carlo; D'Antona, Donato; Nardelli, Giovanni Battista

    2014-07-01

    In modern obstetrics, different pharmacological and non-pharmacological options allow to obtain pain relief during labour, one of the most important goals in women satisfaction about medical care. The aim of this review is to compare all the analgesia administration schemes in terms of effectiveness in pain relief, length of labour, mode of delivery, side effects and neonatal outcomes. A systematic literature search was conducted in electronic databases in the interval time between January 1999 and March 2013. Key search terms included: “labour analgesia”, “epidural anaesthesia during labour” (excluding anaesthesia for Caesarean section), “epidural analgesia and labour outcome” and “intra-thecal analgesia”. 10,331 patients were analysed: 5,578 patients underwent Epidural-Analgesia, 259 patients spinal analgesia, 2,724 combined spinal epidural analgesia, 322 continuous epidural infusion (CEI), 168 intermittent epidural bolus, 684 patient-controlled infusion epidural analgesia and 152 intra-venous patient-controlled epidural analgesia. We also considered 341 women who underwent patient-controlled infusion epidural analgesia in association with CEI and 103 patients who underwent patient-controlled infusion epidural analgesia in association with automatic mandatory bolus. No significant differences occurred among all the available administration schemes of neuraxial analgesia. In absence of obstetrical contraindication, neuraxial analgesia has to be considered as the gold standard in obtaining maternal pain relief during labour. The options available in the administration of analgesia should be known and evaluated together by both gynaecologists and anaesthesiologists to choose the best personalized scheme and obtain the best women satisfaction. Since it is difficult to identify comparable circumstances during labour, it is complicate to standardize drugs schemes and their combinations.

  15. Assessing the effects of vegetation types on carbon storage fifteen years after reforestation on a Chinese fir site

    Science.gov (United States)

    Qinkui Wang; Silong Wang; Jianwei Zhang

    2009-01-01

    Forest ecosystems play a significant role in sequestering carbon (C) in biomass and soils. Plantations established in subtropical China since the 1980s, mainly of Chinese fir (Cunninghamia lanceolata (Lamb.) Hook) in monocultures, have proved to be major C sinks. However, information is lacking about whether mixing Chinese fir with broadleaved tree...

  16. An Analysis of the First Fifteen Years of the Department of Defense Framework for Unmanned Ground Systems

    Science.gov (United States)

    2014-12-01

    teleassisted UGVs. The mid-term focus was on supervised robotics for navigation, recon, surveillance, and target acquisition. The far-term strategy...1991) b. Rapid Runway Repair (RRR) The second project is the rapid runway repair (RRR), which is a teleassisted repair system that can drive to a

  17. The leaching of radioactivity from highly radioactive glass blocks buried below the water table: fifteen years of results

    International Nuclear Information System (INIS)

    Merritt, W.F.

    1976-03-01

    The results from two test burials of high-level fission products incorporated into nepheline syenite glass indicate that the nuclear wastes from fuel processing for a 30,000 MWe nuclear power industry could be incorporated into such glass and stored beneath the water table in the waste management area of Chalk River Nuclear Laboratories (CRNL) without harm to the environment. (author)

  18. Differences Between Patients With Sarcoidosis With and Without Joint Involvement Treated for Fifteen Years in a Third Level Hospital.

    Science.gov (United States)

    Muñoz, Carolina; Restrepo-Escobar, Mauricio; Martínez-Muñoz, Manuel; Echeverri, Andrés; Márquez, Javier; Pinto, Luis Fernando

    2018-02-15

    Sarcoidosis is a complex disease of unknown etiology, with a variable course and highly different forms of presentation. Our objective was to characterize all our patients with sarcoidosis with emphasis on their clinical presentation and to establish differences between patients with sarcoidosis with and without joint involvement. We reviewed the medical records of all patients with a diagnosis of sarcoidosis who were treated at the outpatient or inpatient services of the Pablo Tobón Uribe Hospital in Medellín, Colombia, from January 2002 to April 2017. We identified 22 patients with sarcoidosis. There were joint symptoms in 13 of them. All but one of the patients with sarcoidosis affecting the joints had concomitant skin involvement (92%), which was much less frequent in patients without joint involvement (22%) (odds ratio=4.2; P<.001). Patients with sarcoidosis who have joint involvement have a much higher frequency of concomitant skin involvement. The absence of cutaneous findings in a patient with joint symptoms decreases the likelihood of sarcoidosis. Copyright © 2018 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología. All rights reserved.

  19. Remembrances of the early fifteen years of radiation protection at the National Atomic Energy Commission. Part 2

    International Nuclear Information System (INIS)

    Placer, Alejandro E.

    2005-01-01

    Personal memories on the origin of radiation protection activities in Argentina. This second part covers the period from 1957 to the early sixties and describes the persons and facts that led to the future development of radiation protection in the country [es

  20. Remembrances of the early fifteen years of radiation protection at the National Atomic Energy Commission. Part 3

    International Nuclear Information System (INIS)

    Placer, Alejandro E.

    2005-01-01

    Personal memories on the origin of radiation protection activities in Argentina. This third part covers the period from 1963 to 1973 and describes the persons and facts that led to the future development of radiation protection in the country [es

  1. Fifteen-year follow-up of pulmonary function in individuals heterozygous for the cystic fibrosis phenylalanine-508 deletion

    DEFF Research Database (Denmark)

    Dahl, Morten; Nordestgaard, B G; Lange, P

    2001-01-01

    In a cross-sectional study, we previously showed that cystic fibrosis phenylalanine-508 deletion (DeltaF508) heterozygosity may be overrepresented among individuals with asthma.......In a cross-sectional study, we previously showed that cystic fibrosis phenylalanine-508 deletion (DeltaF508) heterozygosity may be overrepresented among individuals with asthma....

  2. Fifteen years of verticillium wilt of lettuce in america’s salad bowl: a tale of immigration, subjugation and abatement.

    Science.gov (United States)

    Lettuce is a popular leafy vegetable that is globally cultivated. The US ranks second in production, with coastal California producing half of the US supply. In 1995, Verticillium wilt caused by the soil borne fungus Verticillium dahliae was identified as a disease of lettuce in coastal California, ...

  3. A comprehensive literature review reflecting fifteen years of debate regarding the representativity of reverse circulation vs blast hole drill sampling

    DEFF Research Database (Denmark)

    Engström, Karin

    2017-01-01

    Blast hole sampling is widely used for grade control by the mining industry all over the world, both in precious and base metal open pit mining. Blast hole (BH) samples are often regarded as inferior in comparison to “proper drill sampling” like reverse circulation (RC) and diamond (core) drillin...

  4. Biophysics an introduction

    CERN Document Server

    Cotteril, Rodney

    2002-01-01

    Biophysics: An Introduction, is a concise balanced introduction to this subject. Written in an accessible and readable style, the book takes a fresh, modern approach with the author successfully combining key concepts and theory with relevant applications and examples drawn from the field as a whole. Beginning with a brief introduction to the origins of biophysics, the book takes the reader through successive levels of complexity, from atoms to molecules, structures, systems and ultimately to the behaviour of organisms. The book also includes extensive coverage of biopolymers, biomembranes, biological energy, and nervous systems. The text not only explores basic ideas, but also discusses recent developments, such as protein folding, DNA/RNA conformations, molecular motors, optical tweezers and the biological origins of consciousness and intelligence.

  5. "Highly recommended introduction"

    DEFF Research Database (Denmark)

    Christiansen, Ask Vest

    2009-01-01

    by detachment, normatively and morally. Besides researching the actual abuse, individually and in aggregate, they also study structural circumstances that promote the use of drugs in sports; besides evaluations of the efficacy of the anti-doping efforts, they consider the effects of various anti-doping schemes...... on the integrity and privacy of the athletes. Ask Vest Christiansen, himself an internationally renowned scholar in the field, has read a recent, thus detached, introduction to drug use in sports, An Introduction to Drugs in Sport: Addicted to Winning by Ivan Waddington and Andy Smith (Routledge). Christiansen...... finds much to appreciate in the book, and a couple of disconcerting mistakes and misjudgments notwithstanding, he recommends the book as a solid introduction to the problem of doping – knowledgeable, well written and easy to read....

  6. Statistics a complete introduction

    CERN Document Server

    Graham, Alan

    2013-01-01

    Statistics: A Complete Introduction is the most comprehensive yet easy-to-use introduction to using Statistics. Written by a leading expert, this book will help you if you are studying for an important exam or essay, or if you simply want to improve your knowledge. The book covers all the key areas of Statistics including graphs, data interpretation, spreadsheets, regression, correlation and probability. Everything you will need is here in this one book. Each chapter includes not only an explanation of the knowledge and skills you need, but also worked examples and test questions.

  7. Applied energy an introduction

    CERN Document Server

    Abdullah, Mohammad Omar

    2012-01-01

    Introduction to Applied EnergyGeneral IntroductionEnergy and Power BasicsEnergy EquationEnergy Generation SystemsEnergy Storage and MethodsEnergy Efficiencies and LossesEnergy industry and Energy Applications in Small -Medium Enterprises (SME) industriesEnergy IndustryEnergy-Intensive industryEnergy Applications in SME Energy industriesEnergy Sources and SupplyEnergy SourcesEnergy Supply and Energy DemandEnergy Flow Visualization and Sankey DiagramEnergy Management and AnalysisEnergy AuditsEnergy Use and Fuel Consumption StudyEnergy Life-Cycle AnalysisEnergy and EnvironmentEnergy Pollutants, S

  8. Introduction to fuzzy systems

    CERN Document Server

    Chen, Guanrong

    2005-01-01

    Introduction to Fuzzy Systems provides students with a self-contained introduction that requires no preliminary knowledge of fuzzy mathematics and fuzzy control systems theory. Simplified and readily accessible, it encourages both classroom and self-directed learners to build a solid foundation in fuzzy systems. After introducing the subject, the authors move directly into presenting real-world applications of fuzzy logic, revealing its practical flavor. This practicality is then followed by basic fuzzy systems theory. The book also offers a tutorial on fuzzy control theory, based mainly on th

  9. Introduction to nuclear reactions

    International Nuclear Information System (INIS)

    Satchler, G.R.

    1980-01-01

    This introduction to nuclear reaction phenomena is aimed primarily but not exclusively at readers at the undergraduate student level. An overview of the subject is presented in the first two chapters entitled - Some background information and Introduction to nuclear reactions. The third chapter reviews scattering theory with emphasis on the underlying physical ideas and also provides schematic entrees to the more advanced topics. The physical models which have been developed to account for the various aspects of nuclear phenomena are described in more detail in chapter 4. References and exercises are appended to each chapter. (U.K.)

  10. Game theory an introduction

    CERN Document Server

    Barron, E N

    2013-01-01

    An exciting new edition of the popular introduction to game theory and its applications The thoroughly expanded Second Edition presents a unique, hands-on approach to game theory. While most books on the subject are too abstract or too basic for mathematicians, Game Theory: An Introduction, Second Edition offers a blend of theory and applications, allowing readers to use theory and software to create and analyze real-world decision-making models. With a rigorous, yet accessible, treatment of mathematics, the book focuses on results that can be used to

  11. Introduction to the Project

    DEFF Research Database (Denmark)

    Kuhn, Johan M.; Malchow-Møller, Nikolaj; Sørensen, Anders

    In this note a short introduction to the project “Employment Effects of Entrepreneurs” is presented. First, we describe the purpose of the project; second, we present the background; third, we briefly describe the three papers that constitute the output of the project, and fourth, we discuss two ...... important qualifications for the understanding of the contributions and results established in the project.......In this note a short introduction to the project “Employment Effects of Entrepreneurs” is presented. First, we describe the purpose of the project; second, we present the background; third, we briefly describe the three papers that constitute the output of the project, and fourth, we discuss two...

  12. Introduction to nonimaging optics

    CERN Document Server

    Chaves, Julio

    2015-01-01

    Introduction to Nonimaging Optics covers the theoretical foundations and design methods of nonimaging optics, as well as key concepts from related fields. This fully updated, revised, and expanded Second Edition: Features a new and intuitive introduction with a basic description of the advantages of nonimaging opticsAdds new chapters on wavefronts for a prescribed output (irradiance or intensity), infinitesimal étendue optics (generalization of the aplanatic optics), and Köhler optics and color mixingIncorporates new material on the simultaneous multiple surface (SMS) design method in 3-D, int

  13. Fall Protection Introduction, #33462

    Energy Technology Data Exchange (ETDEWEB)

    Chochoms, Michael [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-06-23

    The proper use of fall prevention and fall protection controls can reduce the risk of deaths and injuries caused by falls. This course, Fall Protection Introduction (#33462), is designed as an introduction to various types of recognized fall prevention and fall protection systems at Los Alamos National Laboratory (LANL), including guardrail systems, safety net systems, fall restraint systems, and fall arrest systems. Special emphasis is given to the components, inspection, care, and storage of personal fall arrest systems (PFASs). This course also presents controls for falling object hazards and emergency planning considerations for persons who have fallen.

  14. Acoustics an introduction

    CERN Document Server

    Kuttruff, Heinrich

    2006-01-01

    This definitive textbook provides students with a comprehensive introduction to acoustics. Beginning with the basic physical ideas, Acoustics balances the fundamentals with engineering aspects, applications and electroacoustics, also covering music, speech and the properties of human hearing. The concepts of acoustics are exposed and applied in:room acousticssound insulation in buildingsnoise controlunderwater sound and ultrasoundScientifically thorough, but with mathematics kept to a minimum, Acoustics is the perfect introduction to acoustics for students at any level of mechanical, electrical or civil engineering courses and an accessible resource for architects, musicians or sound engineers requiring a technical understanding of acoustics and their applications.

  15. An Introduction to Malware

    DEFF Research Database (Denmark)

    Sharp, Robin

    2017-01-01

    These notes, intended for use in DTU course 02233 on Network Security, give a short introduction to the topic of malware. The most important types of malware are described, together with their basic principles of operation and dissemination, and defenses against malware are discussed.......These notes, intended for use in DTU course 02233 on Network Security, give a short introduction to the topic of malware. The most important types of malware are described, together with their basic principles of operation and dissemination, and defenses against malware are discussed....

  16. An Introduction to Malware

    DEFF Research Database (Denmark)

    Sharp, Robin

    2007-01-01

    These notes intended for use in DTU course 02233 on Network Security give a short introduction to the topic of malware. The most important types of malware are described, together with their basic principles of operation and dissemination, and defences against malware are discussed.......These notes intended for use in DTU course 02233 on Network Security give a short introduction to the topic of malware. The most important types of malware are described, together with their basic principles of operation and dissemination, and defences against malware are discussed....

  17. Introduction to UAV systems

    CERN Document Server

    Fahlstrom, Paul

    2012-01-01

    Unmanned aerial vehicles (UAVs) have been widely adopted in the military world over the last decade and the success of these military applications is increasingly driving efforts to establish unmanned aircraft in non-military roles. Introduction to UAV Systems, 4th edition provides a comprehensive introduction to all of the elements of a complete Unmanned Aircraft System (UAS). It addresses the air vehicle, mission planning and control, several types of mission payloads, data links and how they interact with mission performance, and launch and recovery concepts. This

  18. Introduction to information processing

    CERN Document Server

    Dietel, Harvey M

    2014-01-01

    An Introduction to Information Processing provides an informal introduction to the computer field. This book introduces computer hardware, which is the actual computing equipment.Organized into three parts encompassing 12 chapters, this book begins with an overview of the evolution of personal computing and includes detailed case studies on two of the most essential personal computers for the 1980s, namely, the IBM Personal Computer and Apple's Macintosh. This text then traces the evolution of modern computing systems from the earliest mechanical calculating devices to microchips. Other chapte

  19. Introduction to magnetochemistry

    CERN Document Server

    Earnshaw, Alan

    2013-01-01

    Introduction to Magnetochemistry provides an introduction to the more important aspects of magnetochemistry. The measurement of magnetic moment has been one of the most consistently useful to coordination chemists. For teaching purposes it provides a simple method of illustrating the ideas of electronic structure, and in research it can provide fundamental information about the bonding and stereochemistry of complexes. The book contains six chapters covering topics such as free atoms and ions, transition metal complexes, crystal field theory, second and third row transition metal complexes, a

  20. Further discoveries in the ever-expanding genus Begonia (Begoniaceae: fifteen new species from Sumatra

    Directory of Open Access Journals (Sweden)

    Mark Hughes

    2015-12-01

    Full Text Available Fifteen new species of Begonia L. from Sumatra are described and illustrated, in Begonia sect. Bracteibegonia (B. beludruvenea M.Hughes sp. nov. and B. jackiana M.Hughes sp. nov., B. sect. Petermannia (B. harauensis Girm. sp. nov., B. sect. Platycentrum (B. leuserensis M.Hughes sp. nov., B. sect. Reichenheimia (B. fluvialis M.Hughes sp. nov., B. halabanensis M.Hughes sp. nov., B. karangputihensis Girm. sp. nov., B. kemumuensis M.Hughes sp. nov., B. korthalsiana Miq. ex M.Hughes sp. nov., B. kudoensis Girm. sp. nov., B. lilliputana M.Hughes sp. nov., B. olivacea Ardi sp. nov., B. raoensis M.Hughes sp. nov., B. simolapensis Ardi sp. nov. and B. sect. Sphenanthera (B. pseudoscottii Girm. sp. nov.. Using the International Union for the Conservation of Nature criteria, 6 are considered to be Least Concern, 5 Vulnerable and 4 Data Deficient. A key to 58 of the 63 currently accepted Begonia species in Sumatra is provided.

  1. 2.1 Introduction

    DEFF Research Database (Denmark)

    Peder Pedersen, Claus

    2017-01-01

    Introduction to chapter on creative spaces for the 'ADAPT-r Creativity Book'. The text reflects on how researching practitioners in the ADAPT-r has frequently been referring to their workspaces as part of their creative practice research. The Chapter also contains a photographic essay by the author...... showing work spaces of researchers at Aarhus School of Architecture...

  2. Introduction to number theory

    CERN Document Server

    Vazzana, Anthony; Garth, David

    2007-01-01

    One of the oldest branches of mathematics, number theory is a vast field devoted to studying the properties of whole numbers. Offering a flexible format for a one- or two-semester course, Introduction to Number Theory uses worked examples, numerous exercises, and two popular software packages to describe a diverse array of number theory topics.

  3. Chemical Safety – Introduction

    CERN Multimedia

    DG Unit

    2009-01-01

    A course of "Chemical Safety – Introduction" will be held in English on 29 May 2009, 9:30-12:00. There are some places left. If you are interested in participating, please register on the Training Catalogue. You will then receive an invitation by email.

  4. Introduction and fundamentals

    International Nuclear Information System (INIS)

    Thomas, R.H.

    1980-01-01

    This introduction discusses advances in the fundamental sciences which underlie the applied science of health physics and radiation protection. Risk assessments in nuclear medicine are made by defining the conditions of exposure, identification of adverse effects, relating exposure with effect, and estimation of the overall risk for ionizing radiations

  5. A Gentle Introduction

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 3; Issue 7. Machine Translation - A Gentle Introduction. Durgesh D Rao. General Article Volume 3 Issue 7 July 1998 pp 61-70. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/003/07/0061-0070 ...

  6. Introduction to Wiener's Article

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 4; Issue 1. Introduction to Wiener's Article. V Rajaraman. Reflections Volume 4 Issue 1 January 1999 pp 80-80. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/004/01/0080-0080. Author Affiliations.

  7. Introduction to Chiral Symmetry

    Energy Technology Data Exchange (ETDEWEB)

    Koch, Volker [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2017-05-09

    These lectures are an attempt to a pedagogical introduction into the elementary concepts of chiral symmetry in nuclear physics. We will also discuss some effective chiral models such as the linear and nonlinear sigma model as well as the essential ideas of chiral perturbation theory. We will present some applications to the physics of ultrarelativistic heavy ion collisionsd.

  8. Introduction to HACCP.

    Science.gov (United States)

    Introduction to HACCP Deana R. Jones, Ph.D. Egg Safety and Quality Research Unit USDA-Agricultural Research Service Russell Research Center Athens, GA Deana.Jones@ars.usda.gov HACCP is an acronym for Hazard Analysis and Critical Control Point and was initially developed by the Pillsbury Company a...

  9. Introduction to quantum groups

    International Nuclear Information System (INIS)

    Monteiro, Marco A.R.

    1994-01-01

    An elementary introduction to quantum groups is presented. The example of Universal Enveloping Algebra of deformed SU(2) is analysed in detail. It is also discussed systems made up of bosonic q-oscillators at finite temperature within the formalism of Thermo-Field Dynamics. (author). 39 refs

  10. Introduction to solitons

    Indian Academy of Sciences (India)

    Abstract. As an introduction to the special issue on nonlinear waves, solitons and their significance in physics are reviewed. The soliton is the first universal concept in nonlinear science. Universality and ubiquity of the soliton concept are emphasized.

  11. 1.0 Introduction

    African Journals Online (AJOL)

    ADDRESSING AFRICAN FEMINISM. H F Chidammodzi. 1.0 Introduction. Popular struggles for democracy and human rights in Africa today have, among other things, precipitated a reflective consciousness upon the status and conditions of women. The African woman herself has become sensitised to the multiple forms.

  12. Introduction: Ideologies of Youth

    African Journals Online (AJOL)

    seriane.camara

    2011-12-01

    Dec 1, 2011 ... nor funding, relief programmes and international aid, these discussions have made the 'youth' the .... to the definition of youth if the social science of Africa intends to do justice to the cultural, historical ... their introduction to capitalist regimes that turned them into cheap labour for the mines or plantations.

  13. Diophantine geometry an introduction

    CERN Document Server

    Hindry, Marc

    2000-01-01

    This is an introduction to diophantine geometry at the advanced graduate level. The book contains a proof of the Mordell conjecture which will make it quite attractive to graduate students and professional mathematicians. In each part of the book, the reader will find numerous exercises.

  14. Introduction to the Project

    DEFF Research Database (Denmark)

    Kuhn, Johan M.; Malchow-Møller, Nikolaj; Sørensen, Anders

    In this note a short introduction to the project “Employment Effects of Entrepreneurs” is presented. First, we describe the purpose of the project; second, we present the background; third, we briefly describe the three papers that constitute the output of the project, and fourth, we discuss two...... important qualifications for the understanding of the contributions and results established in the project....

  15. Introduction to nucleosynthesis

    International Nuclear Information System (INIS)

    Guasp, J.

    1975-01-01

    After a short introduction on stellar evolution, the physical foundations of nucleosynthesis are exposed: H, He, C and O fusion, Si burning and the equilibrium process. The effect of neutrinos in the last stages of stellar evolution and Supernova explosions are treated too. Afterwards the neutron capture process, fast and slow, are considerated concluding with cosmic nucleogenesis and nucleosynthesis in overmasive objects. (author)

  16. An Introduction to Psycholinguistics

    Science.gov (United States)

    Jodai, Hojat

    2011-01-01

    This paper is written to have a preliminary introduction about psycholinguistics. Psycholinguistics or psychology of language is the study of the interrelation between linguistic factors and psychological aspects. The main subject of research in psycholinguistics is the study of cognitive processes that underlie the comprehension and production of…

  17. Generationing Development: an introduction

    NARCIS (Netherlands)

    R.B.C. Huijsmans (Roy)

    2017-01-01

    markdownabstractThis introduction chapter sets out the overall framework informing the volume and surveys the relevant literature. It lays out a relational approach to studying children, youth and development with age and generation as key concepts. This chapter introduces and develops these

  18. Introduction: Adapting Idols

    NARCIS (Netherlands)

    Joost Bruin; dr. Koos Zwaan

    2012-01-01

    Introduction book Adapting Idols Since the first series of Pop Idol aired in the UK just over a decade ago, Idols television shows have been broadcast in more than forty countries all over the world. In all those countries the global Idols format has been adapted to local cultures and production

  19. Introduction to risk assessment

    International Nuclear Information System (INIS)

    Raina, V.M.

    2002-01-01

    This paper gives an introduction to risk assessment. It discusses the basic concepts of risk assessment, nuclear risk assessment process and products, the role of risk assessment products in nuclear safety assurance, the relationship between risk assessment and other safety analysis and risk assessment and safe operating envelope

  20. Introduction to Algorithms

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 1; Issue 9. Introduction to Algorithms Turtle Graphics. R K Shyamasundar. Series Article Volume 1 ... Author Affiliations. R K Shyamasundar1. Computer Science Group Tata Institute of Fundamental Research Homi Bhabha Road Mumbai 400 005, India.

  1. Historiography: an introduction.

    Science.gov (United States)

    Rose, F Clifford

    2002-03-01

    This introduction precedes the four papers given in October 2000 in Copenhagen on analysing problems in the history of the neurosciences. The term historiography can be defined in different ways but means the study, and not simply the writing, of history. Although it goes back two millennia, it is a rapidly developing field as illustrated by the subsequent contributions.

  2. An introduction to radiobiology

    International Nuclear Information System (INIS)

    Nias, A.H.W.; Dimbleby, R.

    1990-01-01

    This text provides an introduction to quantitative radiobiology with emphasis on practical aspects of the subject. Among the topics considered are reparable damage, densely ionizing radiation, normal and malignant cells, and whole body regulation. These and other aspects of radiation biology are described in detail

  3. Introduction to topology

    CERN Document Server

    Mendelson, Bert

    1990-01-01

    Highly regarded for its exceptional clarity, imaginative and instructive exercises, and fine writing style, this concise book offers an ideal introduction to the fundamentals of topology. It provides a simple, thorough survey of elementary topics, starting with set theory and advancing to metric and topological spaces, connectedness, and compactness. 1975 edition.

  4. Introduction to Game Theory

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 9; Issue 3. Introduction to Game Theory. S Ramasubramanian. Book Review Volume 9 Issue 3 March 2004 pp 81-81. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/009/03/0081-0081. Author Affiliations.

  5. An introduction to English grammar

    CERN Document Server

    Nelson, Gerald C

    2013-01-01

    English Language and its usage has become extremely emotive issues in recent years. Recurring discussions in the media have highlighted a growing demand for a return to the study of language after decades of neglect. This book is an introductory descriptive survey, intended for students, teachers and general readers which offers coverage of grammatical topics with sections on spelling, punctuation and exercises.Clear and concise, this much needed third edition of Gerald Nelson and the late Sidney Greenbaum's introduction will be of immense value to students who have little or no experience of

  6. Planets a very short introduction

    CERN Document Server

    Rothery, David A

    2010-01-01

    Planets: A Very Short Introduction demonstrates the excitement, uncertainties, and challenges faced by planetary scientists, and provides an overview of our Solar System and its origins, nature, and evolution. Terrestrial planets, giant planets, dwarf planets and various other objects such as satellites (moons), asteroids, trans-Neptunian objects, and exoplanets are discussed. Our knowledge about planets has advanced over the centuries, and has expanded at a rapidly growing rate in recent years. Controversial issues are outlined, such as What qualifies as a planet? What conditions are required for a planetary body to be potentially inhabited by life? Why does Pluto no longer have planet status? And Is there life on other planets?

  7. Introduction to mathematics of satisfiability

    CERN Document Server

    Marek, Victor W

    2009-01-01

    Although this area has a history of over 80 years, it was not until the creation of efficient SAT solvers in the mid-1990s that it became practically important, finding applications in electronic design automation, hardware and software verification, combinatorial optimization, and more. Exploring the theoretical and practical aspects of satisfiability, Introduction to Mathematics of Satisfiability focuses on the satisfiability of theories consisting of propositional logic formulas. It describes how SAT solvers and techniques are applied to problems in mathematics and computer science as well

  8. An Introduction to Cognitive Musicology

    DEFF Research Database (Denmark)

    Haumann, Niels Trusbak

    2015-01-01

    This historical-scientific introduction to Cognitive Musicology introduces the 150 years of research and discoveries in the psychology of music that partly presuppose the more recent discipline of Cognitive Musicology. Atomistic, Gestalt, functionalist, testing, behaviorist, cognitive......, and neuroscience approaches to the psychological mechanisms underlying music are presented. Thus, it is argued that Cognitive Musicology is partly based on firm historical traditions in the psychology of music. Also discussed is the way in which the combination of interdisciplinary methods from the humanities...... and the natural sciences, which is integrated in Cognitive Musicology, may minimize the limitations of the separate humanities-based or natural science methods....

  9. Cumulative Index to the First Fifteen Semiannual Reports of the Commission to the Congress. January 1947 - 1953

    Energy Technology Data Exchange (ETDEWEB)

    Dean, Gordon

    1954-01-31

    The first fifteen semiannual reports of the United States Atomic Energy Commission to Congress cover the major unclassified activities of the Commission from January 1947 through December 1953. This cumulative name and subject index provides a guide to the information published in these reports.

  10. In vitro antihelmintic effect of fifteen tropical plant extracts on excysted flukes of Fasciola hepatica.

    Science.gov (United States)

    Alvarez-Mercado, José Manuel; Ibarra-Velarde, Froylán; Alonso-Díaz, Miguel Ángel; Vera-Montenegro, Yolanda; Avila-Acevedo, José Guillermo; García-Bores, Ana María

    2015-02-27

    Fasciolosis due to Fasciola hepatica is the most important hepatic disease in veterinary medicine. Its relevance is important because of the major economical losses to the cattle industry such as: reduction in milk, meat and wool production; miscarriages, anemia, liver condemnation and occasionally deaths, are estimated in billons of dollars. The emergence of fluke resistance due to over or under dosing of fasciolides as well as environmental damage produced by the chemicals eliminated in field have stimulated the need for alternative methods to control Fasciola hepatica. The aim of this study was to evaluate the in vitro anthelmintic effect of fifteen tropical plant extracts used in tradicional Mexican medicine, on newly excysted flukes of Fasciola hepatica. The flukes were exposed in triplicate at 500, 250 and 125 mg/L to each extract. The efficacy was assessed as the mortality rate based on the number of live and dead flukes after 24, 48 and 72 h post-exposure. The plants with anthelmintic effect were evaluated once again with a concentration of 375 mg/L in order to confirm the results and to calculate lethal concentrations at 50%, 90% and 99% (LC(50), LC(90), and LC(99)). Plant extracts of Lantana camara, Bocconia frutescens, Piper auritum, Artemisia mexicana and Cajanus cajan had an in vitro anthelmintic effect (P <0.05). The LC(50), LC(90) and LC(99) to A. mexicana, C. cajan and B. frutescens were 92.85, 210.44 and 410.04 mg/L, 382.73, 570.09 and 788.9 mg/L and 369.96, 529.94 and 710.34 mg/L, respectively. It is concluded that five tropical plant extracts had promising anthelmintic effects against F. hepatica. Further studies on toxicity and in vivo biological evaluation in ruminant models might help to determine the anthelmintic potential of these plant extracts.

  11. Environmentalism in the Periphery: Institutional Embeddedness and Deforestation among Fifteen Palm Oil Producers, 1990 – 2012

    Directory of Open Access Journals (Sweden)

    Kent Henderson

    2017-08-01

    Full Text Available Environmental sociologists highlight the exploitative nature of the global capitalist economy where resource extraction from nations in the periphery tends to disproportionately benefit those of the core. From the Brazilian Amazon to mineral-rich Sub-Saharan Africa, the practice of “unequal ecological exchange” persists. Simultaneously, a “global environmental regime” has coalesced as a prominent feature of the contemporary world system. In the post-World War II era, legitimate nation-states must take steps to protect the natural environment and prevent its degradation even at their own economic expense. Stronger national ties to global institutions, particularly international nongovernmental organizations (INGOs consistently yield more positive environmental outcomes. However, previous work suggests that normative expectations for improved environmental practice will be weak or nonexistent in the periphery. We use the case of palm oil production and its relationship to deforestation to provide a more nuanced analysis of the relationship between material and institutional forces in the periphery. Using unbalanced panels of fifteen palm oil producing countries from 1990 to 2012, we find that stronger national ties to world society via citizen memberships in INGOs result in greater primary forest area among palm oil producers. However, this effect is strongest where production is lowest and weakens as production increases. Even in the cases of Indonesia and Malaysia, where palm oil production is substantially higher than any other producer, ties to global institutions are significantly related to reduced forest loss. These results indicate the variable importance of national embeddedness into global institutions within the periphery of the world system.

  12. Fifteen fatal fallacies of financial fundamentalism Quince falacias funestas del fundamentalismo financiero

    Directory of Open Access Journals (Sweden)

    Vickrey William

    1999-06-01

    Full Text Available In this article, Professor Vickrey shows that current economic policy is based on incomplete analyses, counterfactual assumptions, and false analogies. The article examines in detail fifteen fallacies which, taken together, lead to policies which at best generate economic lethargy with unemployment rates close to 5 or 6 percent. For Professor Vickrey, this situation is harmful in that it reduces potential production between 10 and 15 percent even if the loss is distributed in an equitable way among the population; but when it turns into unemployment of 10, 20, and up to 40 percent for the less favored groups, the additional harm in terms of poverty, family breakup, school absence and dropout, illegitimacy,
    drug use, and crime becomes very serious. Thus these policies are like a 'premeditated homicidal fire' and, even worse, when they are carried to their ultimate consequences, in search of 'budgetary equilibrium', they can lead to a deep depression.En este articulo, el profesor Vickrey muestra que la politica economica actual se basa en analisis incompletos, supuestos contrafactuales y analogias falsas. El articulo examina en detalle quince falacias que, en conjunto, llevan a politicas que, en el mejor de los casos, generan un letargo economico con tasas de desempleo cercanas al 5 o 6 por ciento. Para el profesor Vickrey, esta situacion es perjudicial por cuanto reduce la produccion potencial entre un 10 y un 15 por ciento aun asi la perdida de se reparte de forma equitativa entre toda la poblacion; pero cuando se traduce un desempleo de 10, 20 o hasta 40 por ciento para los grupos desfavorecidos, los perjuicios adicionales en terminos de pobreza, ruptura familiar, ausencia y desercion escolar, ilegitimidad, uso de drogas y crimenes llegan a ser muy graves. De modo que estas politicas se asemejan a un "incendio homicida premeditado" y, aun peor, cuando se llevan hasta sus ultimas concecuencias, en busca de un 'presupuesto equilibrado

  13. Introduction to Sporadic Groups

    Directory of Open Access Journals (Sweden)

    Luis J. Boya

    2011-01-01

    Full Text Available This is an introduction to finite simple groups, in particular sporadic groups, intended for physicists. After a short review of group theory, we enumerate the 1+1+16=18 families of finite simple groups, as an introduction to the sporadic groups. These are described next, in three levels of increasing complexity, plus the six isolated ''pariah'' groups. The (old five Mathieu groups make up the first, smallest order level. The seven groups related to the Leech lattice, including the three Conway groups, constitute the second level. The third and highest level contains the Monster group M, plus seven other related groups. Next a brief mention is made of the remaining six pariah groups, thus completing the 5+7+8+6=26 sporadic groups. The review ends up with a brief discussion of a few of physical applications of finite groups in physics, including a couple of recent examples which use sporadic groups.

  14. Introduction to linear elasticity

    CERN Document Server

    Gould, Phillip L

    2013-01-01

    Introduction to Linear Elasticity, 3rd Edition, provides an applications-oriented grounding in the tensor-based theory of elasticity for students in mechanical, civil, aeronautical, and biomedical engineering, as well as materials and earth science. The book is distinct from the traditional text aimed at graduate students in solid mechanics by introducing the subject at a level appropriate for advanced undergraduate and beginning graduate students. The author's presentation allows students to apply the basic notions of stress analysis and move on to advanced work in continuum mechanics, plasticity, plate and shell theory, composite materials, viscoelasticity and finite method analysis. This book also:  Emphasizes tensor-based approach while still distilling down to explicit notation Provides introduction to theory of plates, theory of shells, wave propagation, viscoelasticity and plasticity accessible to advanced undergraduate students Appropriate for courses following emerging trend of teaching solid mechan...

  15. Introduction to Abelian varieties

    CERN Document Server

    Murty, V Kumar

    1993-01-01

    The book represents an introduction to the theory of abelian varieties with a view to arithmetic. The aim is to introduce some of the basics of the theory as well as some recent arithmetic applications to graduate students and researchers in other fields. The first part contains proofs of the Abel-Jacobi theorem, Riemann's relations and the Lefschetz theorem on projective embeddings over the complex numbers in the spirit of S. Lang's book Introduction to algebraic and abelian functions. Then the Jacobians of Fermat curves as well as some modular curves are discussed. Finally, as an application, Faltings' proof of the Mordell conjecture and its intermediate steps, the Tate conjecture and the Shafarevich conjecture, are sketched. - H. Lange for MathSciNet.

  16. Introduction to computer networking

    CERN Document Server

    Robertazzi, Thomas G

    2017-01-01

    This book gives a broad look at both fundamental networking technology and new areas that support it and use it. It is a concise introduction to the most prominent, recent technological topics in computer networking. Topics include network technology such as wired and wireless networks, enabling technologies such as data centers, software defined networking, cloud and grid computing and applications such as networks on chips, space networking and network security. The accessible writing style and non-mathematical treatment makes this a useful book for the student, network and communications engineer, computer scientist and IT professional. • Features a concise, accessible treatment of computer networking, focusing on new technological topics; • Provides non-mathematical introduction to networks in their most common forms today;< • Includes new developments in switching, optical networks, WiFi, Bluetooth, LTE, 5G, and quantum cryptography.

  17. Mind a brief introduction

    CERN Document Server

    Searle, John R

    2004-01-01

    "The philosophy of mind is unique among contemporary philosophical subjects," writes John Searle, "in that all of the most famous and influential theories are false." One of the world's most eminent thinkers, Searle dismantles these theories as he presents a vividly written, comprehensive introduction to the mind. He begins with a look at the twelve problems of philosophy of mind--which he calls "Descartes and Other Disasters"--problems which he returns to throughout the volume, as he illuminates such topics as materialism, consciousness, the mind-body problem, intentionality, mental causation, free will, and the self. The book offers a refreshingly direct and engaging introduction to one of the most intriguing areas of philosophy.

  18. Introduction to modern magnetohydrodynamics

    CERN Document Server

    Galtier, Sébastien

    2016-01-01

    Ninety-nine percent of ordinary matter in the Universe is in the form of ionized fluids, or plasmas. The study of the magnetic properties of such electrically conducting fluids, magnetohydrodynamics (MHD), has become a central theory in astrophysics, as well as in areas such as engineering and geophysics. This textbook offers a comprehensive introduction to MHD and its recent applications, in nature and in laboratory plasmas; from the machinery of the Sun and galaxies, to the cooling of nuclear reactors and the geodynamo. It exposes advanced undergraduate and graduate students to both classical and modern concepts, making them aware of current research and the ever-widening scope of MHD. Rigorous derivations within the text, supplemented by over 100 illustrations and followed by exercises and worked solutions at the end of each chapter, provide an engaging and practical introduction to the subject and an accessible route into this wide-ranging field.

  19. Introduction to Extra Dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Rizzo, Thomas G.; /SLAC

    2010-04-29

    Extra dimensions provide a very useful tool in addressing a number of the fundamental problems faced by the Standard Model. The following provides a very basic introduction to this very broad subject area as given at the VIII School of the Gravitational and Mathematical Physics Division of the Mexican Physical Society in December 2009. Some prospects for extra dimensional searches at the 7 TeV LHC with {approx}1 fb{sup -1} of integrated luminosity are provided.

  20. Introduction to parallel programming

    CERN Document Server

    Brawer, Steven

    1989-01-01

    Introduction to Parallel Programming focuses on the techniques, processes, methodologies, and approaches involved in parallel programming. The book first offers information on Fortran, hardware and operating system models, and processes, shared memory, and simple parallel programs. Discussions focus on processes and processors, joining processes, shared memory, time-sharing with multiple processors, hardware, loops, passing arguments in function/subroutine calls, program structure, and arithmetic expressions. The text then elaborates on basic parallel programming techniques, barriers and race

  1. Differential topology an introduction

    CERN Document Server

    Gauld, David B

    2006-01-01

    Offering classroom-proven results, Differential Topology presents an introduction to point set topology via a naive version of nearness space. Its treatment encompasses a general study of surgery, laying a solid foundation for further study and greatly simplifying the classification of surfaces.This self-contained treatment features 88 helpful illustrations. Its subjects include topological spaces and properties, some advanced calculus, differentiable manifolds, orientability, submanifolds and an embedding theorem, and tangent spaces. Additional topics comprise vector fields and integral curv

  2. Introduction to superstring theory

    Energy Technology Data Exchange (ETDEWEB)

    Nunez, Carmen [Instituto de Astronomia y Fisica del Espacio, Buenos Aires (Argentina)], e-mail: carmen@iafe.uba.ar

    2009-07-01

    This is a very basic introduction to the AdS/CFT correspondence. The first lecture motivates the duality between gauge theories and gravity/string theories. The next two lectures introduce the bosonic and supersymmetric string theories. The fourth lecture is devoted to study Dp-branes and finally, in the fifth lecture I discuss the two worlds: N=4 SYM in 3+1 flat dimensions and type IIB superstrings in AdS{sub 5} x S5. (author)

  3. Introduction to superstring theory

    International Nuclear Information System (INIS)

    Nunez, Carmen

    2009-01-01

    This is a very basic introduction to the AdS/CFT correspondence. The first lecture motivates the duality between gauge theories and gravity/string theories. The next two lectures introduce the bosonic and supersymmetric string theories. The fourth lecture is devoted to study Dp-branes and finally, in the fifth lecture I discuss the two worlds: N=4 SYM in 3+1 flat dimensions and type IIB superstrings in AdS 5 x S5. (author)

  4. Introduction to electronics

    CERN Document Server

    Korneff, Theodore

    1966-01-01

    Introduction to Electronics focuses on the study of electronics and electronic devices. Composed of 14 chapters, the book starts with discussions on dc circuits, including resistance, voltmeter, ammeter, galvanometer, internal resistance, and positive and negative currents. This topic is followed by discussions on ac circuits, particularly addressing voltage and current, average power, resistive load, complex plane, and parallel circuits. Discussions also focus on filters and tuned circuits, diodes, and power supplies. Particularly given attention are the processes, diagrams, and analyses

  5. Internet Governance: An Introduction

    OpenAIRE

    Arthur J. Cordell; Prabir K. Neogi

    2007-01-01

    Internet Governance: An Introduction offers a complete guide to the “ins and outs” of Internet governance. Drawing on a range of international authors Internet Governance is best suited for those seeking an overview of the range of issues involved as the Internet becomes increasingly important to bu siness and to society in general, affecting the daily lives of millions of people around the world.

  6. Introduction to reversible computing

    CERN Document Server

    Perumalla, Kalyan S

    2013-01-01

    Few books comprehensively cover the software and programming aspects of reversible computing. Filling this gap, Introduction to Reversible Computing offers an expanded view of the field that includes the traditional energy-motivated hardware viewpoint as well as the emerging application-motivated software approach. Collecting scattered knowledge into one coherent account, the book provides a compendium of both classical and recently developed results on reversible computing. It explores up-and-coming theories, techniques, and tools for the application of rever

  7. Introduction to nanotheranostics

    CERN Document Server

    Tamil Selvan, Subramanian

    2016-01-01

    This book offers readers an introduction to the current status of nanoparticles and other nanomaterials that have potential applications in theranostics. Above all, it highlights the diagnostic and therapeutic applications of metallic (e.g. Au, Ag), semiconducting quantum dots (e.g. CdSe, CdTe), magnetic (e.g. Fe3O4, FePt, Co), and multifunctional (combination of two or three) nanoparticles. .

  8. Introduction to biomechatronics

    CERN Document Server

    Brooker, Graham

    2012-01-01

    Introduction to Biomechatronics provides fundamental knowledge of mechanical and electronic (mechatronic) components and systems and their interaction with human biology to assist or replace limbs, senses, and even organs damaged by trauma, birth defects, or disease. The first half of the book provides the engineering background to understand all the components of a biomechatronic system: the human subject, stimulus or actuation, transducers and sensors, signal conditioning elements, recording and display, and feedback elements.

  9. Dark matter an introduction

    CERN Document Server

    Majumdar, Debasish

    2015-01-01

    Dark Matter: An Introduction tackles the rather recent but fast-growing subject of astroparticle physics, encompassing three main areas of fundamental physics: cosmology, particle physics, and astrophysics. Accordingly, the book discusses symmetries, conservation laws, relativity, and cosmological parameters and measurements, as well as the astrophysical behaviors of galaxies and galaxy clusters that indicate the presence of dark matter and the possible nature of dark matter distribution.

  10. Introduction to microfabrication

    CERN Document Server

    Franssila, Sami

    2005-01-01

    Microfabrication is the key technology behind integrated circuits, microsensors, photonic crystals, ink jet printers, solar cells and flat panel displays. Microsystems can be complex, but the basic microstructures and processes of microfabrication are fairly simple. Introduction to Microfabrication shows how the common microfabrication concepts can be applied over and over again to create devices with a wide variety of structures and functions.Featuring:* A comprehensive presentation of basic fabrication processes* An emphasis on materials and microstructures, rather than devic

  11. Introduction to neutron scattering

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, W.E. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1996-11-01

    We give here an introduction to the theoretical principles of neutron scattering. The relationship between scattering- and correlation-functions is particularly emphasized. Within the framework of linear response theory (justified by the weakness of the basic interaction) the relation between fluctuation and dissipation is discussed. This general framework explains the particular power of neutron scattering as an experimental method. (author) 4 figs., 4 refs.

  12. Introduction to Q

    International Nuclear Information System (INIS)

    Kellogg, M.; Minor, M.M.; Shlaer, S.; Spencer, N.; Thomas, R.F. Jr.; van der Beken, H.

    1978-06-01

    This manual presents an overview of the Q data-acquisition system. Its purposes are to assist an experimenter in determining whether the system is suited to his needs and to provide an introduction to the more detailed manuals. This system employs a powerful technique for dealing with multiprocessor systems by generating code and communication protocol for two processors from a single source program in a high-level language. Some details of experimental event buffering and distribution are discussed

  13. Introduction to minimax

    CERN Document Server

    Dem'yanov, V F; Louvish, D

    2014-01-01

    This user-friendly text offers a thorough introduction to the part of optimization theory that lies between approximation theory and mathematical programming, both linear and nonlinear. Written by two distinguished mathematicians, the expert treatment covers the essentials, incorporating important background materials, examples, and extensive notes.Geared toward advanced undergraduate and graduate students of mathematical programming, the text explores best approximation by algebraic polynomials in both discrete and continuous cases; the discrete problem, with and without constraints; the gene

  14. Introduction to heat transfer

    CERN Document Server

    SUNDÉN, B

    2012-01-01

    Presenting the basic mechanisms for transfer of heat, Introduction to Heat Transfer gives a deeper and more comprehensive view than existing titles on the subject. Derivation and presentation of analytical and empirical methods are provided for calculation of heat transfer rates and temperature fields as well as pressure drop. The book covers thermal conduction, forced and natural laminar and turbulent convective heat transfer, thermal radiation including participating media, condensation, evaporation and heat exchangers.

  15. Introduction to cosmology

    CERN Document Server

    Roos, Matts

    2015-01-01

    The Fourth Edition of Introduction to Cosmology provides a concise, authoritative study of cosmology at an introductory level. Starting from elementary principles and the early history of cosmology, the text carefully guides the student on to curved spacetimes, special and general relativity, gravitational lensing, the thermal history of the Universe, and cosmological models, including extended gravity models, black holes and Hawking's recent conjectures on the not-so-black holes.

  16. Introduction to QCD

    OpenAIRE

    Skands, Peter

    2012-01-01

    These lectures were originally given at TASI and are directed at a level suitable for graduate students in High Energy Physics. They are intended to give an introduction to the theory and phenomenology of quantum chromodynamics (QCD), focusing on collider physics applications. The aim is to bring the reader to a level where informed decisions can be made concerning different approaches and their uncertainties. The material is divided into five main areas: 1) fundamentals, 2) fixed-order pertu...

  17. Ion implantation - an introduction

    International Nuclear Information System (INIS)

    Townsend, P.D.

    1986-01-01

    Ion implantation is a widely used technique with a literature that covers semiconductor production, surface treatments of steels, corrosion resistance, catalysis and integrated optics. This brief introduction outlines advantages of the technique, some aspects of the underlying physics and examples of current applications. Ion implantation is already an essential part of semiconductor technology while in many other areas it is still in an early stage of development. The future scope of the subject is discussed. (author)

  18. Eleutherodactylus frog introductions to Hawaii

    Science.gov (United States)

    Kraus, Fred; Campbell, Earl W.; Allison, Allen; Pratt, Thane K.

    1999-01-01

    As an oceanic archipelago isolated from continental source areas, Hawaii lacks native terrestrial reptiles and amphibians, Polynesians apparently introduced seven gecko and skink species after discovering the islands approximately 1500 years ago, and another 15 reptiles and five frogs have been introduced in the last century and a half (McKeown 1996). The Polynesian introductions are probably inadvertent because the species involved are known stowaway dispersers (Gibbons 1985; Dye and Steadman 1990), In contrast, most of the herpetological introductions since European contact with Hawaii have been intentional. Several frog species were released for biocontrol of insects (e.g., Dendrobates auratus, Bufo marinus, Rana rugosa, Bryan 1932; Oliver and Shaw 1953), and most of the remaining species are released or escaped pets (e.g., Phelsuma spp., Chamaeleo jacksonii, Iguana iguana, McKeown 1996), Government-approved releases have not occurred for many years, but the rate of establishment of new species has increased in the past few decades because of the importation and subsequent release of pets.

  19. PHEV Market Introduction Workshop Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Weber, Adrienne M [ORNL; Sikes, Karen R [ORNL

    2009-03-01

    The Plug-In Hybrid Electric Vehicle (PHEV) Market Introduction Study Workshop was attended by approximately forty representatives from various stakeholder organizations. The event took place at the Hotel Helix in Washington, D.C. on December 1-2, 2008. The purpose of this workshop was to follow-up last year s PHEV Value Proposition Study, which showed that indeed, a viable and even thriving market for these vehicles can exist by the year 2030. This workshop aimed to identify immediate action items that need to be undertaken to achieve a successful market introduction and ensuing large market share of PHEVs in the U.S. automotive fleet.

  20. Targeted scan of fifteen regions for nonsyndromic cleft lip and palate in Filipino families.

    Science.gov (United States)

    Schultz, R E; Cooper, M E; Daack-Hirsch, S; Shi, M; Nepomucena, B; Graf, K A; O'Brien, E K; O'Brien, S E; Marazita, M L; Murray, J C

    2004-02-15

    Cleft lip with or without cleft palate (CL/P) is a congenital anomaly with variable birth prevalence based on geographic origins, with the highest rates commonly found in Asian populations. About 70% of cases are nonsyndromic (NS), in which the affected individual has no other abnormalities. NS CL/P is a complex disorder with genetic and environmental effects and no specific genetic loci yet confirmed. Fifteen candidate regions were examined for linkage to NS CL/P. Regions were chosen based on previous suggestive linkage and/or association in human families, or suggestive animal model data. Polymorphic markers in these regions were genotyped for analysis on 36 Filipino families comprised of 126 affected and 218 unaffected individuals. An additional 70 families with 149 affecteds were used for replication of suggestive results. Parametric (LOD score) and nonparametric (SIMIBD) linkage analyses were performed as well as transmission disequilibrium test (TDT) analysis. Five markers yielded suggestive results from the 36 families. The parametric LOD scores for the MSX1-CA and D4S1629 were >1.0 and the SIMIBD P values for D6S1029 and RFC1 are suggestive (value of 0.01 for TGFA was significant. Since the Msx1 mouse knockout has cleft palate and MSX1 mutations have been found in rare cases of syndromic CL/P, this locus is especially plausible for linkage. Previous studies have also found linkage of NS CL/P to 4q31 and 6p23. These regions contain several candidate genes, including AP2 at 6p23 and FGF2, BMPR1B, and MADH1 at 4q31. TGFA has both linkage and linkage disequilibrium data supporting it as a candidate gene for NS CL/P. While no region was definitively confirmed for linkage to NS CL/P, the data do support further investigation using larger sample sizes and candidate gene studies at 2p13.2, 4p16.2, 4q31, 6p23, and 16q22-24. Copyright 2003 Wiley-Liss, Inc.

  1. Introduction to analysis

    CERN Document Server

    Gaughan, Edward D

    2009-01-01

    Introduction to Analysis is designed to bridge the gap between the intuitive calculus usually offered at the undergraduate level and the sophisticated analysis courses the student encounters at the graduate level. In this book the student is given the vocabulary and facts necessary for further study in analysis. The course for which it is designed is usually offered at the junior level, and it is assumed that the student has little or no previous experience with proofs in analysis. A considerable amount of time is spent motivating the theorems and proofs and developing the reader's intuition.

  2. Introduction to real analysis

    CERN Document Server

    Schramm, Michael J

    2008-01-01

    This text forms a bridge between courses in calculus and real analysis. It focuses on the construction of mathematical proofs as well as their final content. Suitable for upper-level undergraduates and graduate students of real analysis, it also provides a vital reference book for advanced courses in mathematics.The four-part treatment begins with an introduction to basic logical structures and techniques of proof, including discussions of the cardinality concept and the algebraic and order structures of the real and rational number systems. Part Two presents in-depth examinations of the compl

  3. Introduction to superconductivity

    CERN Document Server

    Rose-Innes, A C

    1978-01-01

    Introduction to Superconductivity differs from the first edition chiefly in Chapter 11, which has been almost completely rewritten to give a more physically-based picture of the effects arising from the long-range coherence of the electron-waves in superconductors and the operation of quantum interference devices. In this revised second edition, some further modifications have been made to the text and an extra chapter dealing with """"high-temperature"""" superconductors has been added. A vast amount of research has been carried out on these since their discovery in 1986 but the results, both

  4. Introduction to superconductivity

    CERN Document Server

    Darriulat, Pierre

    1998-01-01

    The lecture series will address physicists, such as particle and nuclear physicists, familiar with non-relativistic quantum mechanics but not with solid state physics. The aim of this introduction to low temperature superconductivity is to give sufficient bases to the student for him/her to be able to access the scientific literature on this field. The five lectures will cover the following topics : 1. Normal metals, free electron gas, chambers equation. 2. Cooper pairs, the BCS ground state, quasi particle excitations. 3. DC superconductivity, Meissner state, dirty superconductors.4. Self consistent approach, Ginsburg Landau equations, Abrikosov fluxon lattice. 5. Josephson effects, high temperature superconductivity.

  5. Introduction to Heat Pipes

    Science.gov (United States)

    Ku, Jentung

    2015-01-01

    This is the presentation file for the short course Introduction to Heat Pipes, to be conducted at the 2015 Thermal Fluids and Analysis Workshop, August 3-7, 2015, Silver Spring, Maryland. NCTS 21070-15. Course Description: This course will present operating principles of the heat pipe with emphases on the underlying physical processes and requirements of pressure and energy balance. Performance characterizations and design considerations of the heat pipe will be highlighted. Guidelines for thermal engineers in the selection of heat pipes as part of the spacecraft thermal control system, testing methodology, and analytical modeling will also be discussed.

  6. Introduction to cluster dynamics

    CERN Document Server

    Reinhard, Paul-Gerhard

    2008-01-01

    Clusters as mesoscopic particles represent an intermediate state of matter between single atoms and solid material. The tendency to miniaturise technical objects requires knowledge about systems which contain a ""small"" number of atoms or molecules only. This is all the more true for dynamical aspects, particularly in relation to the qick development of laser technology and femtosecond spectroscopy. Here, for the first time is a highly qualitative introduction to cluster physics. With its emphasis on cluster dynamics, this will be vital to everyone involved in this interdisciplinary subje

  7. Introduction to laser technology

    CERN Document Server

    Hitz, C Breck; Hecht, Jeff

    2012-01-01

    The only introductory text on the market today that explains the underlying physics and engineering applicable to all lasersAlthough lasers are becoming increasingly important in our high-tech environment, many of the technicians and engineers who install, operate, and maintain them have had little, if any, formal training in the field of electro-optics. This can result in less efficient usage of these important tools. Introduction to Laser Technology, Fourth Edition provides readers with a good understanding of what a laser is and what it can and cannot do. The book explains what types of las.

  8. Introduction to laser technology

    CERN Document Server

    Hitz, C Breck; Hecht, Jeff; Hitz, C Breck; John Wiley & Sons

    2001-01-01

    Electrical Engineering Introduction to Laser Technology , Third Edition. Would you like to know how a laser works, and how it can be modified for your own specific tasks? This intuitive third edition-previously published as Understanding Laser Technology , First and Second Editions-introduces engineers, scientists, technicians, and novices alike to the world of modern lasers, without delving into the mathematical details of quantum electronics. It is the only introductory text on the market today that explains the underlying physics and engineering applicable to all lasers. A unique combinatio.

  9. An introduction to cosmology

    CERN Document Server

    Narlikar, Jayant Vishnu

    2002-01-01

    The third edition of this successful textbook is fully updated and includes important recent developments in cosmology. It begins with an introduction to cosmology and general relativity, and goes on to cover the mathematical models of standard cosmology. The physical aspects of cosmology, including primordial nucleosynthesis, the astroparticle physics of inflation, and the current ideas on structure formation are discussed. Alternative models of cosmology are reviewed, including the model of Quasi-Steady State Cosmology, which has recently been proposed as an alternative to Big Bang Cosmology.

  10. Cartesian tensors an introduction

    CERN Document Server

    Temple, G

    2004-01-01

    This undergraduate text provides an introduction to the theory of Cartesian tensors, defining tensors as multilinear functions of direction, and simplifying many theorems in a manner that lends unity to the subject. The author notes the importance of the analysis of the structure of tensors in terms of spectral sets of projection operators as part of the very substance of quantum theory. He therefore provides an elementary discussion of the subject, in addition to a view of isotropic tensors and spinor analysis within the confines of Euclidean space. The text concludes with an examination of t

  11. Introduction to biosensors

    Science.gov (United States)

    Bhalla, Nikhil; Jolly, Pawan; Formisano, Nello

    2016-01-01

    Biosensors are nowadays ubiquitous in biomedical diagnosis as well as a wide range of other areas such as point-of-care monitoring of treatment and disease progression, environmental monitoring, food control, drug discovery, forensics and biomedical research. A wide range of techniques can be used for the development of biosensors. Their coupling with high-affinity biomolecules allows the sensitive and selective detection of a range of analytes. We give a general introduction to biosensors and biosensing technologies, including a brief historical overview, introducing key developments in the field and illustrating the breadth of biomolecular sensing strategies and the expansion of nanotechnological approaches that are now available. PMID:27365030

  12. Introduction to QCD

    CERN Document Server

    Skands, Peter

    2013-01-01

    These lectures were originally given at TASI and are directed at a level suitable for graduate students in High Energy Physics. They are intended to give an introduction to the theory and phenomenology of quantum chromodynamics (QCD), focusing on collider physics applications. The aim is to bring the reader to a level where informed decisions can be made concerning different approaches and their uncertainties. The material is divided into five main areas: 1) fundamentals, 2) fixed-order perturbative QCD, 3) Monte Carlo event generators and parton showers, 4) Matching at Leading and Next-to-Leading Order, and 5) Soft QCD physics.

  13. Introduction to asymptotics

    CERN Document Server

    Jones, D S

    1997-01-01

    Many branches of science and engineering involve applications of mathematical analysis. An important part of applied analysis is asymptotic approximation which is, therefore, an active area of research with new methods and publications being found constantly. This book gives an introduction to the subject sufficient for scientists and engineers to grasp the fundamental techniques, both those which have been known for some time and those which have been discovered more recently. The asymptotic approximation of both integrals and differential equations is discussed and the discussion includes hy

  14. An introduction to optimization

    CERN Document Server

    Chong, Edwin K P

    2013-01-01

    Praise for the Third Edition "". . . guides and leads the reader through the learning path . . . [e]xamples are stated very clearly and the results are presented with attention to detail.""  -MAA Reviews  Fully updated to reflect new developments in the field, the Fourth Edition of Introduction to Optimization fills the need for accessible treatment of optimization theory and methods with an emphasis on engineering design. Basic definitions and notations are provided in addition to the related fundamental background for linear algebra, geometry, and calculus.  This new

  15. Introduction to Coordination Chemistry

    CERN Document Server

    Lawrance, Geoffrey Alan

    2010-01-01

    Introduction to Coordination Chemistry examines and explains how metals and molecules that bind as ligands interact, and the consequences of this assembly process. This book describes the chemical and physical properties and behavior of the complex assemblies that form, and applications that may arise as a result of these properties. Coordination complexes are an important but often hidden part of our world?even part of us?and what they do is probed in this book. This book distills the essence of this topic for undergraduate students and for research scientists.

  16. Introduction to nuclear physics

    International Nuclear Information System (INIS)

    Lee, Young Sun

    1987-03-01

    This book deals with nuclear physics with basic introduction, like atomic theory of material, movement theory of material, an atom, natural radioactivity, nuclear atom, electromagnetic waves, X rays, the quantum theory, special commercial theory, wavelength and particle, spectrum and hydrogen atom, meaning of wavelength driven, optics spectrum and electronic distribution, microstructure and Zeeman's effect, X rays spectrum and atom structure, an atomic nucleus, conversion rule of a radioactive element, properties of radiation and interaction with material, artificial nuclear decay and artificial radioactivity, acceleration of electric charge particle, neutron physics, nuclear fission, nuclear fission reactor and a thermonuclear reaction and nuclear fusion.

  17. Introduction to dynamic programming

    CERN Document Server

    Cooper, Leon; Rodin, E Y

    1981-01-01

    Introduction to Dynamic Programming provides information pertinent to the fundamental aspects of dynamic programming. This book considers problems that can be quantitatively formulated and deals with mathematical models of situations or phenomena that exists in the real world.Organized into 10 chapters, this book begins with an overview of the fundamental components of any mathematical optimization model. This text then presents the details of the application of dynamic programming to variational problems. Other chapters consider the application of dynamic programming to inventory theory, Mark

  18. Introduction to cardinal arithmetic

    CERN Document Server

    Holz, M; Weitz, E

    1999-01-01

    This book is an introduction into modern cardinal arithmetic in the frame of the axioms of Zermelo-Fraenkel set theory together with the axiom of choice (ZFC). A first part describes the classical theory developed by Bernstein, Cantor, Hausdorff, König and Tarski between 1870 and 1930. Next, the development in the 1970s led by Galvin, Hajnal and Silver is characterized. The third part presents the fundamental investigations in pcf theory which have been worked out by Shelah to answer the questions left open in the 1970s.Reviews:'The authors aim their text at beginners in set theory. They start

  19. Introduction to cosmology

    CERN Document Server

    Roos, Matts

    2003-01-01

    The Third Edition of the hugely successful Introduction to Cosmology provides a concise, authoritative study of cosmology at an introductory level. Starting from elementary principles and the history of cosmology, the text carefully guides the student on to curved spacetimes, general relativity, black holes, cosmological models, particles and symmetries, and phase transitions. Extensively revised, this latest edition includes broader and updated coverage of distance measures, gravitational lensing and waves, dark energy and quintessence, the thermal history of the Universe, inflation,

  20. Introduction to information retrieval

    CERN Document Server

    Manning, Christopher D; Schütze, Hinrich

    2008-01-01

    Class-tested and coherent, this textbook teaches classical and web information retrieval, including web search and the related areas of text classification and text clustering from basic concepts. It gives an up-to-date treatment of all aspects of the design and implementation of systems for gathering, indexing, and searching documents; methods for evaluating systems; and an introduction to the use of machine learning methods on text collections. All the important ideas are explained using examples and figures, making it perfect for introductory courses in information retrieval for advanced un

  1. Game Theory An Introduction

    CERN Document Server

    Barron, E N

    2008-01-01

    A fundamental introduction to modern game theory from a mathematical viewpoint. Game theory arises in almost every fact of human and inhuman interaction since oftentimes during these communications objectives are opposed or cooperation is viewed as an option. From economics and finance to biology and computer science, researchers and practitioners are often put in complex decision-making scenarios, whether they are interacting with each other or working with evolving technology and artificial intelligence. Acknowledging the role of mathematics in making logical and advantageous decisions, Game

  2. Introduction to continuum mechanics

    CERN Document Server

    Lai, W Michael; Rubin, David

    1996-01-01

    Introduction to Continuum Mechanics is a recently updated and revised text which is perfect for either introductory courses in an undergraduate engineering curriculum or for a beginning graduate course.Continuum Mechanics studies the response of materials to different loading conditions. The concept of tensors is introduced through the idea of linear transformation in a self-contained chapter, and the interrelation of direct notation, indicial notation, and matrix operations is clearly presented. A wide range of idealized materials are considered through simple static and dynamic problems, a

  3. Quantum chemistry an introduction

    CERN Document Server

    Kauzmann, Walter

    2013-01-01

    Quantum Chemistry: An Introduction provides information pertinent to the fundamental aspects of quantum mechanics. This book presents the theory of partial differentiation equations by using the classical theory of vibrations as a means of developing physical insight into this essential branch of mathematics.Organized into five parts encompassing 16 chapters, this book begins with an overview of how quantum mechanical deductions are made. This text then describes the achievements and limitations of the application of quantum mechanics to chemical problems. Other chapters provide a brief survey

  4. Statistics a biomedical introduction

    CERN Document Server

    Brown, Byron Wm

    2009-01-01

    CHAPTER 1: Introduction 1 CHAPTER 2: Elementary Rules of Probability 13 CHAPTER 3: Populations, Samples, and the Distribution of the Sample Mean 37 1. Populations and Distributions 38 2. Sampling from Finite Populations 64 3. The Distribution of the Sample Mean 72 CHAPTER 4: Analysis of Matched Pairs Using Sample Means 85 1. A Confidence Interval for the Treatment Effect 86 2. A Hypothesis Test for the Treatment Effect 96 3. Determining the Sample Size 102 CHAPTER 5: Analysis of the Two-Sample Location Problem Using Sample Means 109 1. A Confidence Interval for the Diffe

  5. Introduction to differentiable manifolds

    CERN Document Server

    Auslander, Louis

    2009-01-01

    The first book to treat manifold theory at an introductory level, this text surveys basic concepts in the modern approach to differential geometry. The first six chapters define and illustrate differentiable manifolds, and the final four chapters investigate the roles of differential structures in a variety of situations.Starting with an introduction to differentiable manifolds and their tangent spaces, the text examines Euclidean spaces, their submanifolds, and abstract manifolds. Succeeding chapters explore the tangent bundle and vector fields and discuss their association with ordinary diff

  6. Introduction to EMC

    CERN Document Server

    Scott, John

    1997-01-01

    This is the clear guide for non-specialists to electromagnetic compatability (EMC), the effects of electromagnetic radiation and the European EMC Directive which is now in force. This book helps by explaining the basic principles of EMC, how it may be controlled in practice through filtering, shielding, appropriate printed circuit board design, and other means. Electrostatic discharge (ESD) and surge protection are discussed. The growing concern about the effects of electromagnetic waves and fields on health are examined in detail.This introduction provides beginners, technical and

  7. Introduction to applied thermodynamics

    CERN Document Server

    Helsdon, R M; Walker, G E

    1965-01-01

    Introduction to Applied Thermodynamics is an introductory text on applied thermodynamics and covers topics ranging from energy and temperature to reversibility and entropy, the first and second laws of thermodynamics, and the properties of ideal gases. Standard air cycles and the thermodynamic properties of pure substances are also discussed, together with gas compressors, combustion, and psychrometry. This volume is comprised of 16 chapters and begins with an overview of the concept of energy as well as the macroscopic and molecular approaches to thermodynamics. The following chapters focus o

  8. Introduction to information science

    CERN Document Server

    Bawden, David

    2012-01-01

    This landmark textbook takes a whole subject approach to Information Science as a discipline. Introduced by leading international scholars and offering a global perspective on the discipline, this is designed to be the standard text for students worldwide. The authors' expert narrative guides you through each of the essential building blocks of information science offering a concise introduction and expertly chosen further reading and resources.Critical topics covered include:foundations: concepts, theories and historical perspectivesorganising and retrieving Information information behaviour,

  9. Theoretical astrophysics an introduction

    CERN Document Server

    Bartelmann, Matthias

    2013-01-01

    A concise yet comprehensive introduction to the central theoretical concepts of modern astrophysics, presenting hydrodynamics, radiation, and stellar dynamics all in one textbook. Adopting a modular structure, the author illustrates a small number of fundamental physical methods and principles, which are sufficient to describe and understand a wide range of seemingly very diverse astrophysical phenomena and processes. For example, the formulae that define the macroscopic behavior of stellar systems are all derived in the same way from the microscopic distribution function. This function it

  10. Introduction to mathematical logic

    CERN Document Server

    Mendelson, Elliott

    2015-01-01

    The new edition of this classic textbook, Introduction to Mathematical Logic, Sixth Edition explores the principal topics of mathematical logic. It covers propositional logic, first-order logic, first-order number theory, axiomatic set theory, and the theory of computability. The text also discusses the major results of Gödel, Church, Kleene, Rosser, and Turing.The sixth edition incorporates recent work on Gödel's second incompleteness theorem as well as restoring an appendix on consistency proofs for first-order arithmetic. This appendix last appeared in the first edition. It is offered in th

  11. Introduction to combinatorial designs

    CERN Document Server

    Wallis, WD

    2007-01-01

    Combinatorial theory is one of the fastest growing areas of modern mathematics. Focusing on a major part of this subject, Introduction to Combinatorial Designs, Second Edition provides a solid foundation in the classical areas of design theory as well as in more contemporary designs based on applications in a variety of fields. After an overview of basic concepts, the text introduces balanced designs and finite geometries. The author then delves into balanced incomplete block designs, covering difference methods, residual and derived designs, and resolvability. Following a chapter on the e

  12. Introduction to Artificial Neural Networks

    DEFF Research Database (Denmark)

    Larsen, Jan

    1999-01-01

    The note addresses introduction to signal analysis and classification based on artificial feed-forward neural networks.......The note addresses introduction to signal analysis and classification based on artificial feed-forward neural networks....

  13. Introduction to the ROOT System

    CERN Multimedia

    CERN. Geneva

    2008-01-01

    Introduction to the ROOT data handling system. ROOT is used in some for or another by all LHC experiments and will be used by all for final data analysis. The introduction gives an overview of the system. Prerequisite knowledge: C++

  14. Human drug metabolism: an introduction

    National Research Council Canada - National Science Library

    Coleman, Michael D

    2010-01-01

    Human Drug Metabolism, An Introduction, Second Edition provides an accessible introduction to the subject and will be particularly invaluable to those who already have some understanding of the life sciences...

  15. Introduction to geometry and relativity

    CERN Document Server

    2013-01-01

    This book provides a lucid introduction to both modern differential geometry and relativity for advanced undergraduates and first-year graduate students of applied mathematics and physical sciences. This book meets an overwhelming need for a book on modern differential geometry and relativity that is student-friendly, and which is also suitable for self-study. The book presumes a minimal level of mathematical maturity so that any student who has completed the standard Calculus sequence should be able to read and understand the book. The key features of the book are: Detailed solutions are provided to the Exercises in each chapter; Many of the missing steps that are often omitted from standard mathematical derivations have been provided to make the book easier to read and understand; A detailed introduction to Electrodynamics is provided so that the book is accessible to students who have not had a formal course in this area; In its treatment of modern differential geometry, the book employs both a modern, c...

  16. Fifteen symposia on microdosimetry: implications for modern particle-beam cancer radiotherapy

    CERN Document Server

    Wambersie, A; Gueulette, J; Pihet, P

    2015-01-01

    The objective of microdosimetry was, and still is, to identify physical descriptions of the initial physical processes of ionising radiation interacting with biological matter which correlate with observed radiobiological effects with a view to improve the understanding of radiobiological mechanisms and effects. The introduction of therapy with particles starting with fast neutrons followed by negative pions, protons and light ions necessitated the application of biological weighting factors for absorbed dose in order to account for differences of the relative biological effectiveness (RBE). Dedicated radiobiological experiments in therapy beams with mammalian cells and with laboratory animals provided sets of RBE values which are used to evaluate empirical ‘clinical RBE values’. The combination of such experiments with microdosimetric measurements in identical conditions offered the possibility to establish semi-empirical relationships between microdosimetric parameters and results of RBE studies.

  17. Introduction to Computational Plasticity

    International Nuclear Information System (INIS)

    Hartley, P

    2006-01-01

    The focus of the book on computational plasticity embodies techniques of relevance not only to academic researchers, but also of interest to industrialists engaged in the production of components using bulk or sheet forming processes. Of particular interest is the guidance on how to create modules for use with the commercial system Abaqus for specific types of material behaviour. The book is in two parts, the first of which contains six chapters, starting with microplasticity, but predominantly on continuum plasticity. The first chapter on microplasticty gives a brief description of the grain structure of metals and the existence of slip systems within the grains. This provides an introduction to the concept of incompressibility during plastic deformation, the nature of plastic yield and the importance of the critically resolved shear stress on the slip planes (Schmid's law). Some knowledge of the notation commonly used to describe slip systems is assumed, which will be familiar to students of metallurgy, but anyone with a more general engineering background may need to undertake additional reading to understand the various descriptions. Chapter two introduces one of several yield criteria, that normally attributed to von Mises (though historians of mechanics might argue over who was first to develop the theory of yielding associated with strain energy density), and its two or three-dimensional representation as a yield surface. The expansion of the yield surface during plastic deformation, its translation due to kinematic hardening and the Bauschinger effect in reversed loading are described with a direct link to the material stress-strain curve. The assumption, that the increment of strain is normal to the yield surface, the normality principle, is introduced. Uniaxial loading of an elastic-plastic material is used as an example in which to develop expressions to describe increments in stress and strain. The full presentation of numerous expressions, tensors and

  18. An introduction to extra dimensions

    International Nuclear Information System (INIS)

    Perez-Lorenzana, Abdel

    2005-01-01

    Models that involve extra dimensions have introduced completely new ways of looking up on old problems in theoretical physics. The aim of the present notes is to provide a brief introduction to the many uses that extra dimensions have found over the last few years, mainly following an effective field theory point of view. Most parts of the discussion are devoted to models with flat extra dimensions, covering both theoretical and phenomenological aspects. We also discuss some of the new ideas for model building where extra dimensions may play a role, including symmetry breaking by diverse new and old mechanisms. Some interesting applications of these ideas are discussed over the notes, including models for neutrino masses and proton stability. The last part of this review addresses some aspects of warped extra dimensions, and graviton localization

  19. Introduction to instrumentation and measurements

    CERN Document Server

    Northrop, Robert B

    2014-01-01

    Weighing in on the growth of innovative technologies, the adoption of new standards, and the lack of educational development as it relates to current and emerging applications, the third edition of Introduction to Instrumentation and Measurements uses the authors' 40 years of teaching experience to expound on the theory, science, and art of modern instrumentation and measurements (I&M). What's New in This Edition: This edition includes material on modern integrated circuit (IC) and photonic sensors, micro-electro-mechanical (MEM) and nano-electro-mechanical (NEM) sensors, chemical and radiation sensors, signal conditioning, noise, data interfaces, and basic digital signal processing (DSP), and upgrades every chapter with the latest advancements. It contains new material on the designs of micro-electro-mechanical (MEMS) sensors, adds two new chapters on wireless instrumentation and microsensors, and incorporates extensive biomedical examples and problems. Containing 13 chapters, this third edition: Describ...

  20. Introduction to Statistically Designed Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Heaney, Mike

    2016-09-13

    Statistically designed experiments can save researchers time and money by reducing the number of necessary experimental trials, while resulting in more conclusive experimental results. Surprisingly, many researchers are still not aware of this efficient and effective experimental methodology. As reported in a 2013 article from Chemical & Engineering News, there has been a resurgence of this methodology in recent years (http://cen.acs.org/articles/91/i13/Design-Experiments-Makes-Comeback.html?h=2027056365). This presentation will provide a brief introduction to statistically designed experiments. The main advantages will be reviewed along with the some basic concepts such as factorial and fractional factorial designs. The recommended sequential approach to experiments will be introduced and finally a case study will be presented to demonstrate this methodology.

  1. Newton versus Ørsted: the delayed introduction of Newtonian physics into Denmark.

    Science.gov (United States)

    Pedersen, O.

    Contents: Introduction. The first sixty years. Professor Jens Kraft. New signals. The formation of Ørsted's thought. Ørsted's "first introduction". The reign of Ørsted. The final years. Conclusion.

  2. Between Landscape and Laboratory – an Introduction

    DEFF Research Database (Denmark)

    A written introduction to a bi-lingual anthology Field_Notes - From Landscape to Laboratory - Maisemasta Laboratorioon. "Every second year the Finnish Society of Bioart invites a significant group of artists and scientists to the Kilpisjärvi Biological Station in Lapland/Finland to work for one...

  3. Grid-group cultural theory: an introduction

    NARCIS (Netherlands)

    Mamadouh, V.

    1999-01-01

    This article offers an introduction to grid-group cultural theory (also known as grid-group analysis, Cultural Theory or theory of socio-cultural viability), an approach that has been developed over the past thirty years in the work of the British anthropologists Mary Douglas and Michael Thompson,

  4. Introduction to Waste Engineering

    DEFF Research Database (Denmark)

    Christensen, Thomas Højlund

    2011-01-01

    Solid waste management as introduced in Chapter 1.1 builds in many ways on engineering. Waste engineering here means the skills and ability to understand quantitatively how a waste management system works in such a detail that waste management can be planned, facilities can be designed and sited...... and systems can be operated in a way that is environmentally sound, technical feasible, economically efficient and socially acceptable. This applies to all scales of relevance: (1) national surveys of energy use and material flows determining the frame for politically setting goals in waste management, (2......) regional plans for waste management, including (3) the selection of main management technologies and siting of facilities, (4) the design of individual technological units and, for example, (5) the operation of recycling schemes within a municipality. This chapter gives an introduction to waste engineering...

  5. Introduction to LCA Methodology

    DEFF Research Database (Denmark)

    2017-01-01

    In order to offer the reader an overview of the LCA methodology in the preparation of the more detailed description of its different phases, a brief introduction is given to the methodological framework according to the ISO 14040 standard and the main elements of each of its phases. Emphasis...... is on the iterative nature of the LCA process with its many feedback loops between the different phases. It is explained how the integrated use of sensitivity analysis helps identify key assumptions and key data and thus ensure effectiveness by directing the focus of the LCA practitioner to those parts of the study...... where additional work contributes most to strengthen the results and conclusions of the study....

  6. Introduction to transonic aerodynamics

    CERN Document Server

    Vos, Roelof

    2015-01-01

    Written to teach students the nature of transonic flow and its mathematical foundation, this book offers a much-needed introduction to transonic aerodynamics. The authors present a quantitative and qualitative assessment of subsonic, supersonic, and transonic flow around bodies in two and three dimensions. The book reviews the governing equations and explores their applications and limitations as employed in modeling and computational fluid dynamics.  Some concepts, such as shock and expansion theory, are examined from a numerical perspective. Others, including shock-boundary-layer interaction, are discussed from a qualitative point of view. The book includes 60 examples and more than 200 practice problems. The authors also offer analytical methods such as Method of Characteristics (MOC) that allow readers to practice with the subject matter.  The result is a wealth of insight into transonic flow phenomena and their impact on aircraft design, including compressibility effects, shock and expansion waves, sho...

  7. Introduction to information retrieval

    CERN Document Server

    Manning, Christopher D; Schütze, Hinrich

    2008-01-01

    Class-tested and coherent, this textbook teaches classical and web information retrieval, including web search and the related areas of text classification and text clustering from basic concepts. It gives an up-to-date treatment of all aspects of the design and implementation of systems for gathering, indexing, and searching documents; methods for evaluating systems; and an introduction to the use of machine learning methods on text collections. All the important ideas are explained using examples and figures, making it perfect for introductory courses in information retrieval for advanced undergraduates and graduate students in computer science. Based on feedback from extensive classroom experience, the book has been carefully structured in order to make teaching more natural and effective. Slides and additional exercises (with solutions for lecturers) are also available through the book's supporting website to help course instructors prepare their lectures.

  8. Introduction to tropical geometry

    CERN Document Server

    Maclagan, Diane

    2015-01-01

    Tropical geometry is a combinatorial shadow of algebraic geometry, offering new polyhedral tools to compute invariants of algebraic varieties. It is based on tropical algebra, where the sum of two numbers is their minimum and the product is their sum. This turns polynomials into piecewise-linear functions, and their zero sets into polyhedral complexes. These tropical varieties retain a surprising amount of information about their classical counterparts. Tropical geometry is a young subject that has undergone a rapid development since the beginning of the 21st century. While establishing itself as an area in its own right, deep connections have been made to many branches of pure and applied mathematics. This book offers a self-contained introduction to tropical geometry, suitable as a course text for beginning graduate students. Proofs are provided for the main results, such as the Fundamental Theorem and the Structure Theorem. Numerous examples and explicit computations illustrate the main concepts. Each of t...

  9. Hyperplane arrangements an introduction

    CERN Document Server

    Dimca, Alexandru

    2017-01-01

    This textbook provides an accessible introduction to the rich and beautiful area of hyperplane arrangement theory, where discrete mathematics, in the form of combinatorics and arithmetic, meets continuous mathematics, in the form of the topology and Hodge theory of complex algebraic varieties. The topics discussed in this book range from elementary combinatorics and discrete geometry to more advanced material on mixed Hodge structures, logarithmic connections and Milnor fibrations. The author covers a lot of ground in a relatively short amount of space, with a focus on defining concepts carefully and giving proofs of theorems in detail where needed. Including a number of surprising results and tantalizing open problems, this timely book also serves to acquaint the reader with the rapidly expanding literature on the subject. Hyperplane Arrangements will be particularly useful to graduate students and researchers who are interested in algebraic geometry or algebraic topology. The book contains numerous exercise...

  10. Introduction: Persistent Modelling

    DEFF Research Database (Denmark)

    Ayres, Phil

    2012-01-01

    of this relationship is becoming increasingly variegated. This is apparent in three principle areas; the duration of active influence that representation can hold in relation to the represented; the means, methods and media through which representations are constructed and used; what it is that is being represented.......This introduction to 'Persistent Modelling – an extended role for architectural representation' identifies how the book probes the relationship between representation and the represented, in an architectural context. It discusses how the book presents an examination and discussion of historical......, familiar contemporary and, perhaps, not so familiar emerging manifestations of this relation. What persists from this probing, fully intact, is that representation and the represented remain inextricably related in our contemporary and emerging practices. What comes into focus is that the nature...

  11. Hospital ethnography: introduction.

    Science.gov (United States)

    van der Geest, Sjaak; Finkler, Kaja

    2004-11-01

    The introduction sets out two central ideas around which this collection of articles on hospital ethnography has been organised. The first is that hospitals are not identical clones of a global biomedical model. Hospitals take on different forms in different cultures and societies. Medical views and technical facilities may vary considerably leading to different diagnostic and therapeutic traditions. The second idea, related to the first, is that biomedicine and the hospital as its foremost institution is a domain where the core values and beliefs of a culture come into view. Hospitals both reflect and reinforce dominant social and cultural processes of their societies. The authors further discuss some methodological and ethical complexities of doing fieldwork in a hospital setting and present brief summaries of the contributions, which deal with hospitals in Ghana, South Africa, Bangladesh, Mexico, Italy, The Netherlands, Papua New Guinea, Egypt and Lebanon.

  12. Introduction to uncertainty quantification

    CERN Document Server

    Sullivan, T J

    2015-01-01

    Uncertainty quantification is a topic of increasing practical importance at the intersection of applied mathematics, statistics, computation, and numerous application areas in science and engineering. This text provides a framework in which the main objectives of the field of uncertainty quantification are defined, and an overview of the range of mathematical methods by which they can be achieved. Complete with exercises throughout, the book will equip readers with both theoretical understanding and practical experience of the key mathematical and algorithmic tools underlying the treatment of uncertainty in modern applied mathematics. Students and readers alike are encouraged to apply the mathematical methods discussed in this book to their own favourite problems to understand their strengths and weaknesses, also making the text suitable as a self-study. This text is designed as an introduction to uncertainty quantification for senior undergraduate and graduate students with a mathematical or statistical back...

  13. Introduction to Waste Management

    DEFF Research Database (Denmark)

    Christensen, Thomas Højlund

    2011-01-01

    Solid waste management is as old as human civilization, although only considered an engineering discipline for about one century. The change from the previous focus on public cleansing of the cities to modern waste management was primarily driven by industrialization, which introduced new materials...... and chemicals, dramatically changing the types and composition of waste, and by urbanization making waste management in urban areas a complicated and costly logistic operation. This book focuses on waste that commonly appears in the municipal waste management system. This chapter gives an introduction to modern...... waste management, including issues as waste definition, problems associated with waste, waste management criteria and approaches to waste management. Later chapters introduce aspects of engineering (Chapter 1.2), economics (Chapter 1.3) and regulation (Chapter 1.4)....

  14. Introduction to special relativity

    International Nuclear Information System (INIS)

    Rindler, W.

    1982-01-01

    This is intended as a text for an introductory course on special relativity; it assumes no prior knowledge of relativity. It is intended for the upper undergraduate level and upwards. The first three chapters take a three-dimensional viewpoint for a simple introduction to topics such as the relativity of simultaneity, length contraction, time dilation, the twin paradox and the appearance of moving objects. For the remaining chapters the strongest possible use is made of four-dimensional techniques. Chapter four deals with space-time, chapters five and six with mechanics and electromagnetism. In these a purely synthetic four-tensor approach is adopted. Pure tensor theory is covered in an appendix. The last chapter is on the mechanics of continua. (U.K.)

  15. Introduction to cosmology

    CERN Document Server

    Ryden, Barbara

    2017-01-01

    This second edition of Introduction to Cosmology is an exciting update of an award-winning textbook. It is aimed primarily at advanced undergraduate students in physics and astronomy, but is also useful as a supplementary text at higher levels. It explains modern cosmological concepts, such as dark energy, in the context of the Big Bang theory. Its clear, lucid writing style, with a wealth of useful everyday analogies, makes it exceptionally engaging. Emphasis is placed on the links between theoretical concepts of cosmology and the observable properties of the universe, building deeper physical insights in the reader. The second edition includes recent observational results, fuller descriptions of special and general relativity, expanded discussions of dark energy, and a new chapter on baryonic matter that makes up stars and galaxies. It is an ideal textbook for the era of precision cosmology in the accelerating universe.

  16. History and General Introduction

    International Nuclear Information System (INIS)

    Dunbar, R.C.

    1991-01-01

    In the domain of analytical mass spectrometry (MS), FT-ICR's place is established as combining particular advantages of extraordinary mass resolution and accuracy, a wide array of sample-ionization techniques, and a uniquely wide range of methods for structure characterization of the primary sample ions. Costs are already attractive compared with other high-performance alternatives, and as both magnets and computers (which comprise much of the expense of FT-ICR hardware) become cheaper and more powerful, the performance/cost ratio for the technique will continue to improve. This paper will provide an introduction to those who have little previous knowledge of the technique; provide an overview of the technique's outstanding areas of scientific and analytical application; and provide some historical perspective on how we reached the present state of the art

  17. Pediatric obesity. An introduction.

    Science.gov (United States)

    Yanovski, Jack A

    2015-10-01

    The prevalence of child and adolescent obesity in the United States increased dramatically between 1970 and 2000, and there are few indications that the rates of childhood obesity are decreasing. Obesity is associated with myriad medical, psychological, and neurocognitive abnormalities that impact children's health and quality of life. Genotypic variation is important in determining the susceptibility of individual children to undue gains in adiposity; however, the rapid increase in pediatric obesity prevalence suggests that changes to children's environments and/or to their learned behaviors may dramatically affect body weight regulation. This paper presents an overview of the epidemiology, consequences, and etiopathogenesis of pediatric obesity, serving as a general introduction to the subsequent papers in this Special Issue that address aspects of childhood obesity and cognition in detail. Published by Elsevier Ltd.

  18. I-Introduction

    International Nuclear Information System (INIS)

    1998-01-01

    In this report, each sector starts with an introduction presenting the state of each sector in Lebanon, followed by the methodology adopted in order to compute emissions of greenhouse gases by sources and removals by sinks, in accordance with IPCC guidelines, complemented by experts' assumptions in estimating greenhouse gases and finally accompanied by the IPCC sectoral tables which present the result obtained in each sector. The report ends with an 'Appendices' chapter which includes all worksheets, showing the computations made resulting in emitted or removed greenhouse gas quantities. This executive summary described in the IPCC summary presents the main results obtained in each sector. In the last paragraph, the global warming potential of the greenhouse gases emitted in Lebanon in 1994 is provided for three calculated time horizons, based on the '1995 IPCC technical summary of working group I' report. (au)

  19. Solar energy an introduction

    CERN Document Server

    Mackay, Michael E

    2015-01-01

    Solar Energy presents an introduction to all aspects of solar energy, from photovoltaic devices to active and passive solar thermal energy conversion, giving both a detailed and broad perspective of the field. It is aimed at the beginner involved in solar energy or a related field, or for someone wanting to gain a broader perspective of solar energy technologies. A chapter considering solar radiation, basic principles applied to solar energy, semiconductor physics, and light absorption brings the reader on equal footing with the technology of either solar generated electrical current or useful heat. Details of how a solar cell works and then production of current from a photovoltaic device is discussed. Characterization of a solar cell is examined, allowing one the ability to interpret the current-voltage relation, followed by discussion of parameter extraction from this relation. This information can be used to understand what limits the performance of a given solar cell with the potential to optimize its pe...

  20. An introduction to superhydrophobicity.

    Science.gov (United States)

    Shirtcliffe, Neil J; McHale, Glen; Atherton, Shaun; Newton, Michael I

    2010-12-15

    This paper is derived from a training session prepared for COST P21. It is intended as an introduction to superhydrophobicity to scientists who may not work in this area of physics or to students. Superhydrophobicity is an effect where roughness and hydrophobicity combine to generate unusually hydrophobic surfaces, causing water to bounce and roll off as if it were mercury and is used by plants and animals to repel water, stay clean and sometimes even to breathe underwater. The effect is also known as The Lotus Effect(®) and Ultrahydrophobicity. In this paper we introduce many of the theories used, some of the methods used to generate surfaces and then describe some of the implications of the effect. Copyright © 2009 Elsevier B.V. All rights reserved.