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Sample records for intraocular del segmento

  1. Cuerpo extraño intraocular en el segmento posterior Intraocular foreign bodies in the posterior segment

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    Diley Pérez García

    2012-01-01

    Full Text Available El trauma causado por cuerpo extraño intraocular es una de las principales causas de pérdida visual severa. Técnicamente es un trauma penetrante con permanencia del agente agresor dentro del globo ocular. Constituye una verdadera emergencia oftalmológica, pues puede ocasionar ceguera aún cuando se realiza un diagnóstico y tratamiento adecuados. Se realizó esta revisión para proponer un algoritmo de trabajo con el propósito de maximizar la recuperación anatómica y funcional después de una lesión de este tipo. La conducta a seguir ante este paciente requiere un tratamiento guiado por la apreciación del mecanismo del daño, naturaleza, localización y tamaño del cuerpo extraño; los conocimientos y la disposición del equipamiento necesario para el tratamiento quirúrgico y los cuidados posoperatorios. Existe controversia en cuanto al momento de extracción del cuerpo extraño; sin embargo, se debe realizar una conducta. La profilaxis de la endoftalmitis con antibióticos sistémicos es recomendada y la intravítrea de antibiótico debe ser considerada en los pacientes de alto riesgo. Se debe realizar el diagnóstico precoz o detección posoperatoria temprana de complicaciones como el desprendimiento de retina, endoftalmitis y la proliferación vítreorretiniana, que se han asociado con un pobre pronóstico visual.Intraocular foreign bodies are a major cause for severe visual loss. By technical definition, it consists of a form of penetrating ocular trauma, characterized by the persistence of the traumatic agent inside the eye, and is considered an ophthalmic emergency, since it may cause blindness even if good diagnosis and treatment are followed. This review was made to submit a management algorithm that can maximize the anatomical and functional outcomes after this type of injury. The management of these patients requires taking into account the mechanism of eye injury, the nature, the location and the size of the foreign body

  2. Iris en sayuela signo clínico nuevo asociado al síndrome tóxico del segmento anterior: a new clinical sign associated to the anterior segment toxic syndrome Iris in underskirt

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    Iván Hernández López

    2010-01-01

    Full Text Available OBJETIVO: Presentar un nuevo signo clínico como resultado del desprendimiento gigante del epitelio pigmentado posterior del iris en el curso de un síndrome tóxico del segmento anterior tras una cirugía de catarata. MÉTODOS: Presentamos un paciente intervenido de catarata mediante facoemulsificación con implante de lente intraocular de cámara posterior plegable, sin incidencias ni complicaciones transoperatorias. Se le realizó evaluación biomicroscópica en el posoperatorio inmediato diagnosticándosele un síndrome tóxico del segmento anterior asociado a un desprendimiento gigante del epitelio pigmentado posterior del iris. Se tomaron fotos durante la evolución del paciente para documentar este raro signo clínico. RESULTADOS: Al provocar la dilatación pupilar farmacológica nos encontramos con la retracción de todas las capas anteriores del iris, mostrando por debajo al epitelio pigmentado posterior del iris sinequiado al lente intraocular y tan extensamente desprendido que simulaba un segundo iris. No encontramos este hallazgo clínico reportado en la literatura revisada. Denominamos este signo como iris en sayuela. CONCLUSIONES: El desprendimiento del epitelio pigmentado posterior del iris constituye un hallazgo clínico que puede aparecer raramente asociado al síndrome tóxico del segmento anterior y cuando es muy extenso puede presentarse de forma insólita como el signo del iris en sayuela.OBJECTIVE: To present a new clinical sign as a result of a huge posterior pigmented epithelium detachment of the iris in the course of at toxic anterior segment syndrome after a successful cataract surgery. METHOD: A patient who had undergone a cataract surgery by phacoemulsification with posterior chamber foldable intraocular lens implantation, without any incidence or transoperative complication. He was evaluated through biomicroscopy in the immediate postoperative period where a huge posterior pigmented epithelium detachment of the iris

  3. Divulgación de Informaciones por Segmento: Panorama de la Aplicación del CPC 22

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    Eliandro Schvirck

    2013-01-01

    Full Text Available El objetivo de la pesquisa fue trazar un panorama de la divulgación de segmentos en las demostraciones financieras de las compañías abiertas que operan en el Brasil, publicadas en 2010, primer año de vigencia del CPC 22. Para eso se procuró identificar cómo fueron definidos y cuántos son los segmentos publicados, además de analizar tales resultados en relación a características corporativas de la empresa: tamaño, sector de actuación y status de listado de la compañía en los niveles de gobernanza corporativa. Se trata de pesquisa bibliográfica y documental con foco descriptivo. El análisis de los datos fue realizado en notas explicativas de 81 compañías abiertas seleccionadas entre las mayores empresas, en la edición 2010 de la Revista Melhores e Maiores (Mejores y Mayores. El análisis de los datos fue realizado con estadística descriptiva y análisis de correlación. Los resultados de la pesquisa mostraron que hay empresas que no hicieron ninguna referencia a informaciones por segmentos. La definición de los segmentos atendió predominantemente al criterio de línea de negocios, y el 27% de las compañías agruparon las actividades en un único segmento. El análisis de la correlación mostró que solamente el tamaño del activo presentó relacionamiento significante y positivo con las características de definición y cantidad de segmentos publicados. Fue constatado que hay gran heterogeneidad en las estructuras de los informes por segmento publicados.

  4. Divulgación de Informaciones por Segmento: Panorama de la Aplicación del CPC 22

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    Eliandro Schvirck

    2013-06-01

    Full Text Available El objetivo de la pesquisa fue trazar un panorama de la divulgación de segmentos en las demostraciones financieras de las compañías abiertas que operan en el Brasil, publicadas en 2010, primer año de vigencia del CPC 22. Para eso se procuró identificar cómo fueron definidos y cuántos son los segmentos publicados, además de analizar tales resultados en relación a características corporativas de la empresa: tamaño, sector de actuación y status de listado de la compañía en los niveles de gobernanza corporativa. Se trata de pesquisa bibliográfica y documental con foco descriptivo. El análisis de los datos fue realizado en notas explicativas de 81 compañías abiertas seleccionadas entre las mayores empresas, en la edición 2010 de la Revista Melhores e Maiores (Mejores y Mayores. El análisis de los datos fue realizado con estadística descriptiva y análisis de correlación. Los resultados de la pesquisa mostraron que hay empresas que no hicieron ninguna referencia a informaciones por segmentos. La definición de los segmentos atendió predominantemente al criterio de línea de negocios, y el 27% de las compañías agruparon las actividades en un único segmento. El análisis de la correlación mostró que solamente el tamaño del activo presentó relacionamiento significante y positivo con las características de definición y cantidad de segmentos publicados. Fue constatado que hay gran heterogeneidad en las estructuras de los informes por segmento publicados.

  5. UN SEGMENTO DEL TURISMO INTERNACIONAL EN AUGE: EL TURISMO DE CAZA

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    Juan Ignacio Rengifo Gallego

    2008-01-01

    Full Text Available El número de turistas internacionales viene creciendo de forma continuada desde que existen fuentes estadísticas. Este crecimiento, que no sólo ha sido cuantitativo, sino espacial, ha ido acompañado de una segmentación del mercado en función de las motivaciones. Entre estos segmentos se halla el turismo cinegético, modalidad que ha experimentado un importante crecimiento en los últimos años por diversos motivos. Este incremento ha ido asociado a la movilidad de un porcentaje importante de cazadores de Europa y Estados Unidos, a la existencia de una gran variedad de especies cinegéticas en el mundo que se distribuyen de forma irregular por el territorio y al desarrollo de un entramado empresarial que participa en la comercialización de la caza.

  6. Reemplazo del esófago con segmentos pediculados de yeyuno

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    Alejandro García Gutiérrez

    1998-04-01

    Full Text Available Se presentan 42 esofagoplastias con segmentos pediculados de yeyuno. Se exponen las indicaciones, los principales detalles de la técnica, las complicaciones, la mortalidad y los resultados tardíos. En el 80,9 % de los pacientes la indicación fue la acalasia (megaesófago o fracaso de la técnica de Heller y la estenosis no dilatable secundaria a la esofagitis por reflujo. En 4 pacientes se usó una nueva técnica por una vía combinada, abdominal y torácica derecha. La complicación más frecuente fue la dehiscencia de la anastomosis esofagoyeyunal (6 pacientes con 2 fallecimientos. La mortalidad posoperatoria fue de 12,0 %, la cual disminuyó a 5,0 % en los últimos 20 pacientes operados. El segmento yeyunal interpuesto cumplió eficientemente las funciones de tránsito y esfinteriana del esófago. Se concluye que esta técnica se debe emplear para el reemplazo del esófago distal en las estenosis benignas que no pueden ser resueltas con métodos más conservadores y excepcionalmente, en otros procesos patológicos, y para las sustituciones totales y subtotales del esófago, cuando no existe otra alternativa2 esophagoplastias with pedunculated segments of jejunum were presented. The indications, the main details of the technique, the complications, mortality and the late results are exposed. In 80,9 % of the patients the indications were achalasia (megaesophagus or failure of Heller`s technique and the nondilatable stenosis to reflux esophagitis. A new technique by a combined, abdominal and right thoracic route was used in 4 patients. The dehiscence of the esophagojejunal anastomosis was the most common complication (6 patients with 2 deaths. Postoperative mortality was 12.0 %, which decreased to 5.0 % in the last 20 patients operated on. The interposed jejunal segment fulfilled efficiently the transit and sphincteral functions of the esophagus. It is concluded that this technique should be used to replace the distal esophagus in bening

  7. Simulación y análisis de un segmento de proceso. Parte 1: planteamiento del problema

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    Daniel Bogoya Maldonado

    1992-09-01

    Full Text Available Aquí se presenta el primero de una serie de trabajos encaminados a ilustrar las características y potencialidades de la simulación matemática de un segmento de proceso químico en estado estable, aplicada en microcomputadores digitales, con miras al análisis y diseño de procesos. La serie consiste en: formular un problema de estructura básica, para resolverlo a la luz de las técnicas modular secuencial y modular simultánea; analizar los efectos de aceleración de convergencia y de inicialización de los procesos de cálculo numérico iterativo; y analizar el comportamiento de las variables de operación del segmento.

  8. Internacionalización de PYMES argentinas orientadas a segmentos no masivos del mercado en países desarrollados

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    González, Andrea; Hallak, Juan Carlos

    2013-01-01

    El trabajo analiza la inserción internacional de PYMES argentinas orientadas a segmentos no masivos del mercado en países desarrollados en sectores de tecnología media y baja. Este tipo de inserción involucra productos que se caracterizan por su alto grado de calidad y/o customización. Basados en estudios realizados en siete sectores productores de bienes o servicios que poseen estas características, describimos dos tipos diferentes de inserción. La primera es la exportación de bienes diseñad...

  9. CLONACIÓN Y FILOGENIA MOLECULAR DE UN SEGMENTO DEL GEN CODANTE DE LA ACTINA DE MYRCIARIA DUBIA “CAMU-CAMU”: UN CANDIDATO PARA GEN DE REFERENCIA

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    Juan Castro Gómez

    2012-12-01

    Full Text Available Myrciaria dubia “camu-camu” es un frutal amazónico caracterizado por su amplia variación de vitamina C. Pero los estudios genético moleculares que puedan explicar esta variación son limitados. Por ello nuestro objetivo fue realizar la clonación y filogenia molecular de un segmento del gen codante de la actina de M. dubia. Las muestras fueron obtenidas de la colección de germoplasma del INIA. Luego, el ARN fue purificado y mediante RT-PCR con cebadores degenerados se amplificó un segmento del gen. En base a la secuencia obtenida se diseñaron cebadores específicos para PCR en tiempo real. Los resultados muestran que se ha aislado, clonado y secuenciado un segmento del gen codante de actina de M. dubia y detectado su expresión en hojas, pulpa y cáscara de M. dubia. Así, con el soporte de herramientas bioinformáticas y uso de técnicas de biología molecular hemos aislado, clonado y secuenciado un segmento del gen codante de la actina de M. dubia. Asimismo, los análisis realizados muestran que el gen se expresa y presenta niveles similares de expresión en hojas, pulpa y cáscara de M. dubia. Sin embargo, es necesario realizar más experimentos a fin de verificar su estabilidad de expresión.

  10. Experiencia del tratamiento de espondilolistesis lumbar degenerativa de un solo segmento con espaciador interespinoso

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    Garza,Rodrigo Félix; Lagarda Cuevas,Juan; Maqueda,Mauro Francisco Chavez; Bernaldez,Guillermo Iván Ladewig

    2013-01-01

    OBJETIVO: Evaluar a un año el resultado del uso de espaciadores dinámicos en listésis grado I de Meyerding utilizando la escala de incapacidad de Oswestry. MÉTODOS: Se revisa el historial electrónico y radiográfico de los pacientes según criterios en el período de enero 2008 a diciembre 2010, con el propósito de realizar un estudio de cohortes, retrospectivo, longitudinal y observacional. RESULTADOS: El Oswestry prequirúrgico fue de 3.4% leve, 55.2% moderado y 41.4% severo; mientras que el po...

  11. Comportamiento del Intervalo QT corregido prolongado en el síndrome coronario agudo, sin elevación del segmento ST

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    Amauris Modesto Valera Sales

    2015-12-01

    Full Text Available Se realizó un estudio descriptivo transversal prospectivo, para determinar el comportamiento del intervalo QT corregido prolongado, en pacientes con síndrome coronario agudo sin elevación del segmento ST, en el Centro Diagnóstico Integral “Los Arales”, San Diego, año 2009. El universo fue de 48 pacientes y la muestra incluyó a 29 pacientes con ECG normal o sin nuevos cambios isquémicos. Al ingreso se determinaron los valores del intervalo QT corregido, las variables demográficas, antecedentes personales, niveles enzimáticos de CK-MB y el score TIMI. Estos resultados se correlacionaron con la aparición de eventos clínicos (muerte, infarto no fatal y revascularización un mes después del ingreso. De los 29 pacientes analizados sólo 11 (38% presentaron eventos clínicos, mientras que los restantes 18 (62% no los tuvieron. Los pacientes con eventos presentaron valores del iQTc más prolongados por encima del punto de corte. En ambos grupos predominó el sexo masculino y el grupo de edad más frecuente fue el de 60 a 69 años. El tabaquismo, la hipertensión y la hipercolesterolemia fueron los más prevalentes para ambos grupos, así como el uso previo de aspirina. La estratificación de riesgo TIMI y los parámetros basales en los pacientes estudiados fueron mayores y revelan un mayor porcentaje en el grupo con eventos clínicos. Los resultados demuestran que el iQTc predice eventos adversos cardiovasculares hasta 30 días después del ingreso.

  12. Experiencia del tratamiento de espondilolistesis lumbar degenerativa de un solo segmento con espaciador interespinoso

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    Rodrigo Félix Garza

    2013-01-01

    Full Text Available OBJETIVO: Evaluar a un año el resultado del uso de espaciadores dinámicos en listésis grado I de Meyerding utilizando la escala de incapacidad de Oswestry. MÉTODOS: Se revisa el historial electrónico y radiográfico de los pacientes según criterios en el período de enero 2008 a diciembre 2010, con el propósito de realizar un estudio de cohortes, retrospectivo, longitudinal y observacional. RESULTADOS: El Oswestry prequirúrgico fue de 3.4% leve, 55.2% moderado y 41.4% severo; mientras que el posquirúrgico fue de 79.3% leve y 20.7% moderado. La cirugía realizada más común fue exploración y liberación con un 72.4%, presentando discectomía únicamente el 27.6%. Los pacientes presentaron dolor irradiado a miembro pélvico derecho en el 37.9%, miembro pélvico izquierdo 44.8% y a ambos miembros pélvicos en un 17.2%. Se presentó dolor posquirúrgico irradiado a miembro pélvico únicamente en el 2.4% siendo que el 100% de los casos presentaron algún tipo de dolor irradiado. Se utilizó espaciador DIAM en 79.3% y Wallis en 20.7% CONCLUSIONES: El tratamiento con espaciador interespinoso presenta un bajo índice de reintervención y por lo menos a un año presenta mejoría significativa en el índice de incapacidad.

  13. Níveis de PCR são maiores em pacientes com síndrome coronariana aguda e supradesnivelamento do segmento ST do que em pacientes sem supradesnivelamento do segmento ST Niveles de PCR son mayores en pacientes con síndrome coronario agudo y supradesnivel del segmento ST que en pacientes sin supradesnivel del segmento ST CRP levels are higher in patients with ST elevation than non-ST elevation acute coronary syndrome

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    Syed Shahid Habib

    2011-01-01

    Full Text Available FUNDAMENTO: Há grande interesse no uso de proteína C-reativa de alta sensibilidade (PCR-as para avaliação de risco. Altos níveis de PCR-as no início da síndrome coronária aguda (SCA, antes da necrose tecidual, pode ser um marcador substituto para comorbidades cardiovasculares. OBJETIVO: Dessa forma, nosso objetivo foi estudar diferentes medidas de seguimento de níveis de PCR-as em pacientes com SCA e comparar as diferenças entre infarto do miocárdio sem elevação do segmento ST (NSTEMI com pacientes apresentando elevação do segmento ST (STEMI. MÉTODOS: Este é um estudo observacional. Dos 89 pacientes recrutados, 60 apresentavam infarto agudo do miocárdio (IAM. Três níveis seriados de PCR-us, a nível basal na hospitalização antes de 12 horas após inicio dos sintomas, níveis de pico 36-48 horas após hospitalização e níveis de acompanhamento após 4 a 6 semanas foram analisados e comparados entre pacientes com (IAMCSST e sem supradesnivelamento do segmento ST (IAMSSST. RESULTADOS: Pacientes com IAMCSST tinham IMC significantemente mais alta quando comparados com pacientes IAMSSST. Os níveis de creatino quinase fração MB (CK-MB e aspartato aminotransferase (AST eram significantemente mais altos em pacientes com IAMCSST quando comparados com pacientes com IAMSSST (pFUNDAMENTO: Hay gran interés en el uso de proteína C-reactiva de alta sensibilidad (PCR-as para evaluación de riesgo. Altos niveles de PCR-as en el comienzo del síndrome coronario agudo (SCA, antes de la necrosis tisular, puede ser un marcador sustituto para comorbilidades cardiovasculares. OBJETIVO: De esa forma, nuestro objetivo fue estudiar diferentes medidas de seguimiento de niveles de PCR-as en pacientes con SCA y comparar las diferencias entre infarto de miocardio sin elevación del segmento ST (NSTEMI con pacientes presentando elevación del segmento ST (STEMI. MÉTODOS: Este es un estudio observacional. De los 89 pacientes reclutados, 60

  14. Impacto sobre la morbilidad y mortalidad de la terapia farmacol??gica empleada durante las primeras 24 horas del s??ndrome coronario agudo con elevaci??n del segmento ST complicado con parada cardiorrespiratoria

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    Aguilar Cruz, Iv??n

    2012-01-01

    INTRODUCCI??N El infarto agudo de miocardio con elevaci??n del segmento ST (IAMCEST) es una de las principales causas de morbimortalidad en la actualidad, una de las bases de su tratamiento es la reperfusi??n farmacol??gica mediante los agentes trombol??ticos. En aquellas situaciones donde el IAMCEST sufre como complicaci??n una parada cardiorrespiratoria (PCR), administrar f??rmacos trombol??ticos como tratamiento es controvertido. OBJETIVOS 1. Determinar el efecto del tratamient...

  15. Oferta y demanda en el mercado turístico homosexual: una propuesta de estrategias de intercambio para la mejora del marketing en el segmento

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    Caryn Moner Korflür

    2007-01-01

    Full Text Available La demanda turística homosexual presenta características diferenciales, y necesidades y motivaciones específicas a las que la gran mayoría de empresas del sector turístico no han sabido y/o podido responder. El presente trabajo trata de identificar los principales tipos de empresas u organizaciones que actúan en este mercado y que constituyen la oferta turística, definir las peculiaridades de la demanda turística homosexual en cuanto a sus necesidades y expectativas, y exponer una serie de estrategias de marketing, ya sea segmentación, posicionamiento o mezcla de marketing, a seguir por aquellas empresas del sector turístico que deseen orientarse hacia el segmento homosexual.

  16. ¿Puede la frecuencia cardíaca ser un estimador del consumo de oxígeno para segmentos corporales?

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    Juan C. Velásquez

    2015-01-01

    Introducción: La frecuencia cardíaca es un indicador que se usa con frecuencia para la estimación del consumo de oxígeno. Ha sido empleado para evaluar la carga física global sin embargo su uso para evaluar el trabajo que no involucra todo el cuerpo no ha sido lo suficientemente comprobado. Objetivo: Determinar la relación entre el consumo de oxígeno por segmentos corporales y la frecuencia cardíaca. Métodos: Se estableció la relación entre frecuencia cardíaca, el consumo de oxígeno y el porc...

  17. Impacto sobre la morbilidad y mortalidad de la terapia farmacológica empleada durante las primeras 24 horas del síndrome coronario agudo con elevación del segmento ST complicado con parada cardiorrespiratoria

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    Aguilar Cruz, Iván

    2013-01-01

    INTRODUCCIÓNEl infarto agudo de miocardio con elevación del segmento ST (IAMCEST) es una de las principales causas de morbimortalidad en la actualidad, una de las bases de su tratamiento es la reperfusión farmacológica mediante los agentes trombolíticos. En aquellas situaciones donde el IAMCEST sufre como complicación una parada cardiorrespiratoria (PCR), administrar fármacos trombolíticos como tratamiento es controvertido. OBJETIVOS1. Determinar el efecto del tratamiento trombolítico en la...

  18. ANÁLISIS DEL SEGMENTO DE LA TELEFONÍA MÓVIL EN MÉXICO: IUSACELL

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    Miguel Angel Ixtláhuac-Baumbach

    2015-04-01

    Full Text Available El objetivo de este trabajo es analizar la industria de las telecomunicaciones concentrándonos en el segmento de la telefonía móvil en México y en el papel que la empresa Iusacell juega en éste. Se toma como punto de partida la teoría basada en la industria para la gestión estratégica empresarial, mediante el análisis de la concentración que este mercado de competencia oligopólica presenta. Los métodos utilizado para determinar el nivel de concentración son el Índice de Herfidal y Hirschmann (2012, así como el Índice de Dominancia (1999, posteriormente se analizan los resultados obtenidos, mismos con los que se hace uso de la teoría de juegos para determinar posibles estrategias que puedan ayudar a la empresa en cuestión a expandir su mercado o en el proceso de planeación estratégica, los cuales pueden ser atendidos por los administradores de la firma.

  19. Propuesta de Estrategias de Marketing Emocional del Sector Juguetero en el Segmento infantil para mejorar la compra, la lealtad hacia la marca y la relación padre-hijo.

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    Pérez Franco, Verónica de Jesús.

    2015-01-01

    El objetivo de esta investigación consiste en diseñar una propuesta de marketing emocional que identifique los factores de decisión de compra, para reforzar la relación padre-hijo, logrando así la lealtad hacia la marca. La investigación analiza los factores que influyen en la selección de un producto del sector del juguete dentro del segmento infantil. El método de investigación aplicado es el análisis cualitativo con un alcance exploratorio y un diseño no experimental, dentro del cual el in...

  20. Caracterización del mercado de arrendamientos urbano para el segmento de la población de bajos ingresos

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    Jorge Enrique Torres Ramírez

    2008-01-01

    Full Text Available Siguiendo los preceptos de la economía urbana, la mayor parte de las necesidades habitacionales se atiende con los servicios derivados de los inmuebles que integran el stock conformado históricamente, representando la oferta y demanda de edificaciones nuevas una proporción mínima del mercado total. Así, los mercados de unidades usadas y, especialmente, los arrendamientos, constituyen segmentos que concentran un volumen de transacciones cuya dimensión, en términos físicos y económicos, representa el mayor componente del mercado total de edificaciones. Los resultados de esta investigación permiten hacer un reconocimiento al aporte del mercado de arrendamientos sobre los niveles actuales de calidad habitacional y de vida en Colombia. Puede plantearse así que sin esta oferta, generada por los hogares de manera directa y en gran parte por formas de producción social, el stock habitacional estaría aún más rezagado respecto de las necesidades habitacionales actuales de los hogares colombianos. En Colombia, el mercado de arrendamientos correspondiente a los hogares de menores ingresos ofrece también un potencial de desarrollo atractivo para los empresarios del sector de la edificación urbana y de la intermediación inmobiliaria. El stock debe crecer más rápido y esta forma de tenencia tiene posibilidades concretas de alojar una importante oferta formal actualmente inexistente.

  1. Posición efectiva del lente intraocular en la facoemulsificación diagnosticado por biomicroscopia ultrasónica Effective position of the intraocular lens diagnosed with ultrasonic biomicroscopy in phacoemulsification

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    Juan Raúl Hernández Silva

    2010-12-01

    Full Text Available OBJETIVO: Determinar la posición efectiva del lente intraocular en la facoemulsificación diagnosticado por biomicroscopia ultrasónica y su relación con la "sorpresa refractiva" posquirúrgica. MÉTODOS: Se realizó un estudio descriptivo y prospectivo de una muestra de 176 ojos de 100 pacientes operados de catarata por facoemulsificación con la técnica de Pre chop, en el Servicio de Microcirugía Ocular del Instituto Cubano de Oftalmología "Ramón Pando Ferrer", a los que se le determinó la posición efectiva del lente intraocular en la facoemulsificación diagnosticado por biomicroscopia ultrasónica y su relación con la "sorpresa" refractiva posquirúrgica. RESULTADOS: La mayoría de los pacientes estudiados, fueron del sexo masculino de la tercera edad, se diagnóstico la posición efectiva del lente intraocular en saco-surco por biomicroscopia ultrasónica, con lo que se logró la mejor agudeza visual corregida posoperatoria en todos los grupos de estudio, la distancia de la cara posterior del iris al lente intraocular, diagnosticada por biomicroscopia ultrasónica, en pacientes con lente intraocular en saco capsular demostró un valor constante, la mayoría de pacientes normo corregidos tenían el lente intraocular en saco capsular, los lente intraocular ubicados en la posición saco-surco, cuya háptica se encontraba con mayor angulación, tenían un cilindro posoperatorio promedio mayor, no se encontraron diferencias significativas entre el cilindro posoperatorio promedio obtenido. CONCLUSIONES: Queda demostrada la importancia de la biomicroscopia ultrasónica en la determinación de la posición del lente intraocular en los pacientes operados. Es determinante la localización del lente intraocular en el defecto refractivo posoperatorio, se destaca en la posición saco surco la existencia de un cilindro posoperatorio mayor.OBJECTIVE: To determine the effective position of the intraocular lens in the phacoemulsiphication diagnosed

  2. NUEVOS SEGMENTOS TURÍSTICO CULTURALES. UNA APROXIMACIÓN AL COMPORTAMIENTO DEL CONSUMIDOR TURÍSTICO CINEMATOGRÁFICO

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    María Lorena Rodríguez Campo

    2013-01-01

    Full Text Available En esta investigación se analiza el perfil del turista, su actitud hacia la comercialización, sus intenciones comportamentales y los motivos o razones para consumir turismo cinemato- gráfico. Utilizando una muestra de 484 entrevistados, se comprueba la existencia de una acti- tud positiva hacia el producto, un interés hacia las acciones promocionales de los destinos a través de los largometrajes y la existencia de una serie de motivos que se deben conocer para poder adaptar el producto eficazmente a las necesidades de sus potenciales consumidores y aumentar su satisfacción.

  3. Análisis del proceso de minería de datos sobre la base de datos Bioinformática de segmentos de la proteína p53, asociada a la actividad cancerígena

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    Franco Simonetti

    2011-03-01

    Full Text Available Se estudió la utilización de estrategias para afrontar el problema del desbalanceo y la alta dimensionalidad de los registros que habitualmente forman parte de las bases de datos en el área bioinformática. Se tomó como caso de estudio la base de datos de segmentos de la proteína p53; sobre dicha base se construyen modelos con el fin de identificar si corresponden a patrones activos o inactivos. El problema del desbalanceo se abordó a través de una red neuronal no supervisada, y el de la selección de variables para reducir la alta dimensionalidad, a partir de una combinación de métodos con diferentes enfoques. Experimentos preliminares del modelo propuesto en datos estándar muestran resultados promisorios.

  4. Evaluación de la exposición al riesgo por vibraciones en el segmento mano brazo en compañías del sector metalmecánico

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    Giovanni de Jesús Arias-Castro

    Full Text Available El objetivo del estudio consistió en la medición y evaluación de las aceleraciones originadas por herramientas vibrátiles tales como: pulidoras, amoladoras, taladros, entre otras, y su comparación con los límites de exposición permisibles registrados en la norma ISO 5349 de 2002 para el segmento corporal mano brazo. El estudio se desarrolló en cuatro (4 empresas del sector metalmecánico de la Ciudad de Cali, que inicialmente obligó a realizar una visita preliminar con el fin de seleccionar los procesos y herramientas e identificar las personas expuestas. Desde el punto de vista físico y fisiológico, los componentes estudiados fueron: la aceleración, velocidad y amplitud que son los parámetros asociados a vibraciones, además de la dirección en términos vectoriales, según la postura del segmento corporal involucrado y el grado de compromiso de los sistemas biomecánicos y fisiológicos del ser humano. A través del estudio se pudo evidenciar que las evaluaciones realizadas a 15 tipos de herramientas no sobrepasaron los límites permisibles de exposición establecidos en la Conferencia Americana de Higienistas Industriales Gubernamentales de los Estados Unidos ACGIH 2014, que corresponde a 2. 8 m/s². En la Empresa A, se pudo establecer que el nivel de aceleración más elevado lo presentó la Pulidora Dewalt con un valor de 0. 796571 m/s², para la Empresa B, en el caso del mismo equipo presentó una aceleración de 0. 6653 m/s², en el caso de la Empresa C, la aceleración más significativa la presentó una Pulidora Bosh con una aceleración de 0. 5857 m/s², por último, en la Empresa D con una aceleración de 0,4048 m/s², la Esmeriladora. En el artículo se realiza un resumen de los conceptos más importantes relacionados con vibraciones en el segmento corporal mano brazo, así como de los equipos y herramientas utilizados para su respectiva medición y evaluación.

  5. Análisis del comportamiento del segmento lumbar, no artrodesado, en escoliosis idiopática del adolescente de curva Lenke tipo 1 Análise do comportamento do segmento lombar sem artrodese em escoliose idiopática do adolescente com curvatura de Lenke tipo 1 Analysis of the behavior of the lumbar segment without spinal fusion in adolescent idiopathic scoliosis with curvature of lenke type 1

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    Nicolás Siderakis

    2012-06-01

    Full Text Available OBJETIVO: Determinar el comportamiento del segmento lumbar, no artrodesado, en el plano coronal luego de fusiones torácicas selectivas en pacientes con escoliosis idiopática del adolescente con curvas Lenke 1. MÉTODOS: Se evaluaron 21 pacientes con un seguimiento promedio de 29,71 meses (rango: 24-60 meses mediante análisis clínico y radiográfico retrospectivos de pacientes que presentaron escoliosis idiopáticas del adolescente, con curvas Lenke tipo 1 (ABC. RESULTADOS: En todos los pacientes, en los que se produjo un desequilibrio en el plano coronal, se constató la progresión del valor angular de la curva lumbar no artrodesada al final del seguimiento. CONCLUSIÓN: La curva lumbar no artrodesada progresó al final del seguimiento, en todos los pacientes con desequilibrio confirmado en el plano coronal (3/21.OBJETIVO: Determinar o comportamento do segmento lombar sem artrodese no plano coronal, após fusões torácicas seletivas na escoliose idiopática do adolescente com curvaturas de Lenke 1. MÉTODOS: Foram avaliados 21 pacientes com acompanhamento médio de 29,71 meses (faixa: 24 a 60 meses, por meio de análise clínica e radiográfica retrospectiva de pacientes que apresentaram escoliose idiopática do adolescente com curvaturas de Lenke tipo 1 (ABC. RESULTADOS: Constatou-se aumento do ângulo da curva lombar sem artrodese no final do acompanhamento em todos os pacientes que apresentaram desequilíbrio no plano coronal. CONCLUSÃO: O total dos pacientes nos quais se confirmou desequilíbrio no plano coronal (3/21 apresentaram progressão da curva lombar sem artrodese no final do acompanhamento.OBJECTIVE: To determine the outcome of lumbar segment without arthrodesis in the coronal plane, after selective thoracic fusions for with curvature of Lenke type 1 adolescent idiopathic scoliosis with curvature of Lenke type 1. METHODS: Twenty one patients were evaluated, with a mean follow-up of 29.71 months (range: 24-60 months with

  6. Cálculo del poder de la lente intraocular mediante biometría ultrasónica

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    Yileika Elías García

    Full Text Available Objetivo: caracterizar el comportamiento del cálculo de la lente intraocular mediante biometría ultrasónica. Métodos: se realizó un estudio descriptivo y prospectivo, con un grupo de pacientes atendidos por el Servicio de Catarata del Centro Oftalmológico «Enrique Cabrera», que recibieron tratamiento quirúrgico por catarata con implante de lente intraocular, mediante técnica de Blumenthal. La muestra se conformó con 160 ojos y se estudiaron las variables: sorpresa refractiva, edad, longitud axial y promedio queratométrico según resultado refractivo, poder dióptrico de la lente y componente esférico según edad. Resultados: como resultados más sobresalientes, se obtuvo que el 78,7 % no presentó error en el cálculo de la lente, la mayoría de los pacientes tenían 60 años y más, predominó el rango de longitud axial entre 22 y 24,4 (67,5 %, el promedio queratométrico de 43 a 44,99 (64,3 %, el poder dióptrico del lente de + 20 a + 23 dioptrías (48,2 % y el componente esférico entre 0,00 y +/-1,00 dioptrías (78,8%. Conclusiones: se considera que la biometría ultrasónica resulta adecuada para el cálculo correcto del lente.

  7. Escore de risco Dante Pazzanese para síndrome coronariana aguda sem supradesnivelamento do segmento ST Score de riesgo dante pazzanese para síndrome coronario agudo sin supradesnivel del segmento ST Dante Pazzanese risk score for non-st-segment elevation acute coronary syndrome

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    Elizabete Silva dos Santos

    2009-10-01

    Full Text Available FUNDAMENTO: Em síndrome coronariana aguda (SCA, é importante estimar a probabilidade de eventos adversos. OBJETIVO: Desenvolver um escore de risco em uma população brasileira com SCA sem supradesnivelamento do segmento ST (SST. MÉTODOS: Foram avaliados prospectivamente 1.027 pacientes em um centro brasileiro de cardiologia. Um modelo de regressão logística múltipla foi desenvolvido para prever o risco de morte ou de (reinfarto em 30 dias. A acurácia preditiva do modelo foi determinada pelo C statistic. RESULTADOS: O evento combinado ocorreu em 54 pacientes (5,3%. O escore foi criado pela soma aritmética de pontos dos preditores independentes, cujas pontuações foram designadas pelas respectivas probabilidades de ocorrência do evento. As seguintes variáveis foram identificadas: aumento da idade (0 a 9 pontos; antecedente de diabete melito (2 pontos ou de acidente vascular cerebral (4 pontos; não utilização prévia de inibidor da enzima conversora da angiotensina (1 ponto; elevação da creatinina (0 a 10 pontos; e combinação de elevação da troponina I cardíaca e depressão do segmento ST (0 a 4 pontos. Foram definidos quatro grupos de risco: muito baixo (até 5 pontos; baixo (6 a 10 pontos; intermediário (11 a 15 pontos; e alto risco (16 a 30 pontos. O C statistic para a probabilidade do evento foi de 0,78 e para o escore de risco em pontuação de 0,74. CONCLUSÃO: Um escore de risco foi desenvolvido para prever morte ou (reinfarto em 30 dias em uma população brasileira com SCA sem SST, podendo facilmente ser aplicável no departamento de emergência.FUNDAMENTO: En el síndrome coronario agudo (SCA, es importante estimar la probabilidad de eventos adversos. OBJETIVO: Desarrollar un score de riesgo en una población brasileña con SCA sin supradesnivel del segmento ST (SST. MÉTODOS: Se evaluaron prospectivamente 1.027 pacientes en un centro brasileño de cardiología. Un modelo de regresión logística múltiple se

  8. Guía de práctica clínica sobre el tratamiento trombolítico del infarto agudo del miocardio con elevación del segmento ST en la primera asistencia médica

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    Maikel Santos Medina

    2015-11-01

    Full Text Available Se realizó una Guía de Prácticas Clínicas sobre el tratamiento trombolítico en pacientes con infarto agudo del miocardio con elevación del segmento ST  en la primera asistencia médica, en Las Tunas, con el objetivo de uniformar las conductas terapéuticas, relacionadas con la terapia trombolítica, a los pacientes con infarto agudo del miocardio en la atención primaria de salud, y de este modo aumentar la trombolisis prehospitalaria en esta provincia. Se abordaron las indicaciones, contraindicaciones, dosis de la Estreptoquinasa,  manejo de las complicaciones y el tratamiento suplementario.

  9. Análisis del proceso de minería de datos sobre la base de datos Bioinformática de segmentos de la proteína p53, asociada a la actividad cancerígena

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    Alejandro Hadad

    2011-11-01

    Full Text Available Se estudió la utilización de estrategias para afrontar el problema del desbalanceo y la alta dimensionalidad de los registros que habitualmente forman parte de las bases de datos en el área bioinformática. Se tomó como caso de estudio la base de datos de segmentos de la proteína p53; sobre dicha base se construyen modelos con el fin de identificar si corresponden a patrones activos o inactivos. El problema del desbalanceo se abordó a través de una red neuronal no supervisada, y el de la selección de variables para reducir la alta dimensionalidad, a partir de una combinación de métodos con diferentes enfoques. Experimentos preliminares del modelo propuesto en datos estándar muestran resultados promisorios.

  10. Obstrucción microvascular derivada de la resonancia margnética cardiaca tras un infarto miocárdico con elevación del ST –asociación con marcadores de necrosis cardiaca y cambios del segmento ST

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    Husser, Oliver

    2013-01-01

    Este trabajo, que se dividió en tres partes, pretendió determinar la asociación entre la obstrucción microvascular (MVO) estimada mediante resonancia magnética cardiaca (RMC) con determinados marcadores ampliamente disponibles en el contexto del infarto agudo de miocardio con elevación del segmento-ST (IAMCEST). La RMC permite una exhaustiva evaluación de los pacientes con IAMCEST. En este sentido, la aparición de MVO ha mostrado ser un factor asociado a episodios cardiovascula...

  11. Efectividad del cálculo del poder dióptrico de la lente intraocular con interferometría parcialmente coherente Effectiveness of the intraocular lens power calculation using the partial coherent interferometry

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    Imalvet Santiesteban García

    2010-06-01

    Full Text Available OBJETIVO: Comparar la efectividad del cálculo del poder dióptrico de la lente intraocular con IOL Master y el método de biometría por aplanación convencional. MÉTODOS: Se seleccionó una muestra de 100 ojos (pacientes mediante un muestreo simple aleatorio, en el Servicio de Catarata del Centro de Microcirugía Ocular, con diagnóstico de catarata unilateral o bilateral en la consulta preoperatorio, desde marzo hasta septiembre de 2006. Se clasificaron en dos grupos según el método utilizado para el cálculo de la lente intraocular. Se analizaron las variables: longitud axial media preoperatoria, promedio queratométrico preoperatorio, componente esférico esperado y obtenido, agudeza visual sin corrección y mejor agudeza visual corregida preoperatoria y posoperatoria. El análisis estadístico de los resultados se realizó mediante un análisis de varianza, la prueba t de Student de comparación de medias para datos pareados y chi cuadrado. Se utilizó un nivel de confiabilidad de 95 %. RESULTADOS: Entre los principales resultados se encontró que la diferencia de las longitudes axiales entre los métodos IOL Master y biometría por aplanación A-Scan fue estadísticamente significativa. La agudeza visual sin corrección aumentó cuatro líneas y la mejor agudeza visual corregida seis líneas en el posoperatorio de los pacientes del grupo I. El 90 % de los pacientes del grupo I, o sea, los calculados con IOL Master quedaron en la emetropía en cuanto al componente esférico. CONCLUSIONES: Se evidenció una diferencia significativa e inferior a la encontrada en estudios internacionales entre las longitudes axiales preoperatorias halladas mediante los métodos IOL Master y biometría por aplanación; resultaron superiores las calculadas por IOL Master. Se obtuvo ganancia en las líneas de la Cartilla de Snellen tanto de la agudeza visual sin corrección como la mejor agudeza visual corregida en ambos grupos (superior en el grupo II

  12. MECANISMOS ELECTROFISIOLÓGICOS DE LA ELEVACIÓN DEL SEGMENTO ST DURANTE EL INFARTO AGUDO DE MIOCARDIO. HIPÓTESIS ACTUAL / Electrophysiological mechanisms of the st segment elevation during acute myocardial infarction. Current hypothesis

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    Raimundo Carmona Puerta

    2010-12-01

    Full Text Available Resumen El origen de la elevación del segmento ST elevado durante el infarto agudo de miocardio (IMA ha sido motivo de controversia. Con el avance de la electrofisiología cardíaca básica, hoy puede suponerse con alto grado de fiabilidad, las bases iónicas que generan la modificación del electrocardiograma clínico. A partir de una heterogeneidad eléctrica que existe en condiciones normales la isquemia miocárdica aguda, induce a una exacerbación de este comportamiento fisiológico y crea gradientes eléctricos transmurales significativos, que producen vectores potentes de corriente desde el endocardio al epicardio. Una respuesta diferente desde el punto de vista electrofisiológico, ante tal estímulo anormal, crea el sustrato funcional para tal discrepancia eléctrica a través del espesor de las paredes cardíacas. / Abstract The origin of the ST segment elevation during acute myocardial infarction (AMI has been the object of controversy. The advances in basic cardiac electrophysiology has made possible to assume, with a high degree of reliability, the ionic bases that generate the clinical electrocardiogram change. Starting from an electrical heterogeneity that exists in normal conditions, the acute myocardic ischemia induces an exacerbation of this physiological behavior and creates significant transmural electric gradients, which produces powerful electrical current vectors from the endocardium to the epicardium. A different response from the electrophysiological point of view, in the presence of such abnormal stimuli, creates a functional substratum for such an electric discrepancy through the thickness of the cardiac walls.

  13. A importância de um EGC normal em síndromes coronarianas agudas sem supradesnivelamento do segmento ST La importancia de un ECG normal en síndromes coronarios agudos sin supradesnivel del segmento ST The importance of a normal ECG in non-ST elevation acute coronary syndromes

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    Rogério Teixeira

    2010-01-01

    Full Text Available FUNDAMENTO: O eletrocardiograma (ECG de admissão tem um grande impacto no diagnóstico e tratamento de síndromes coronarianas agudas (SCA sem supradesnivelamento do segmento ST. OBJETIVO: Avaliar o impacto do ECG de admissão no prognóstico da SCA sem supradesnivelamento de ST. População: estudo prospectivo, contínuo, observacional, de 802 pacientes com SCA sem supradesnivelamento de ST de um único centro. MÉTODOS: Os pacientes foram divididos em 2 grupos: A (n=538 - ECG Anormal e B (n=264 - ECG Normal. ECG Normal era sinônimo de ritmo sinusal sem alterações isquêmicas agudas. Um seguimento clínico de um ano foi realizado tendo como alvo todas as causas de mortalidade e a taxa de eventos cardíacos adversos maiores (MACE. RESULTADOS: Os pacientes do Grupo A eram mais velhos (68,7±11,7 vs. 63,4±12,7 anos, pFUNDAMENTO: El electrocardiograma (ECG de ingreso tiene un gran impacto en el diagnóstico y tratamiento de síndromes coronarios agudos (SCA sin supradesnivel del segmento ST. OBJETIVO: Evaluar el impacto del ECG de ingreso en el pronóstico del SCA sin supradesnivel de ST. MÉTODOS: Población: estudio prospectivo, continuo, observacional, de 802 pacientes con SCA sin supradesnivel de ST de un único centro. Los pacientes se dividieron en 2 grupos: A (n=538 - ECG Anormal y B (n=264 - ECG Normal. ECG Normal era sinónimo de ritmo sinusal sin alteraciones isquémicas agudas. Se realizó un seguimiento clínico de un año teniendo como objetivo todas las causas de mortalidad y la tasa de eventos cardíacos adversos mayores (MACE. RESULTADOS: Los pacientes del Grupo A eran más viejos (68,7±11,7 vs 63,4±12,7 años, pBACKGROUND: Admission ECG has a major impact on the diagnosis and management of non-ST elevation acute coronary syndromes (ACS. OBJECTIVE: To assess the impact of the admission ECG on prognosis over non-ST ACS. Population: prospective, continuous, observational study of 802 non-ST ACS patients from a single center

  14. Tratamento de uma coorte de pacientes com infarto agudo do miocárdio com supradesnivelamento do segmento ST Tratamiento de una cohorte de pacientes con infarto agudo de miocardio con supradesnivel del segmento ST Treatment of a cohort of patients with acute myocardial infarction and ST-segment elevation

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    Jamil da Silva Soares

    2009-06-01

    Full Text Available FUNDAMENTO: Trombólise e angioplastia transluminal coronariana (ATC primária são técnicas bem estabelecidas, mas grande parte dos pacientes com infarto agudo do miocárdio com supradesnivelamento do segmento ST (IAM com SST não as recebem quando do atendimento hospitalar. OBJETIVO: Descrever tratamentos inicial e final e desfechos de uma coorte com IAM com SST. MÉTODOS: Analisados, da internação até a alta, 158 pacientes com IAM com SST, de uma população total de 351 pacientes internados com (SCA nos hospitais de Campos dos Goytacazes, entre 2004 e 2006. RESULTADOS: Dos 158 pacientes com IAM com SST, 67,7% chegaram ao hospital nos primeiros 180 minutos, 81,3% em 360 minutos e 8,4% após doze horas. Realizados 148 estudos cinecoronariográficos (93,7%. Observadas lesões de mais de 70% em 266 territórios arteriais. Tratamento inicial foi ATC em 41(26%, trombolíticos em 50 (32%, com 80% de sucesso. Tratamento clínico em 67 (42%. Cerca de 35% dos pacientes deveriam ser trombolizados mas não o foram. No tratamento final foram 93 ATCs, 89 delas com sucesso angiográfico (95,7, sangramento 2 (2,2, oclusão subaguda 2 (2,2%, dissecção tronco 1 (1,1, pseudo aneurisma 1 (1,1. Nenhum óbito durante angioplastia; na evolução, houve dois óbitos (2,1%. Doze pacientes submetidos a cirurgia de revascularização miocárdica (CRM. Tratamento clínico 53 (33%, com 11 óbitos (20,7%. Letalidade global 9,5%, consideradas as três formas de tratamento. CONCLUSÃO: Pacientes atendidos em tempo adequado para reperfusão, porém 1/3 deles não recebeu o procedimento. Tratamento predominante foi ATC, com baixa morbidade. Dois óbitos na evolução. Baixa letalidade global.FUNDAMENTO: La trombólisis y la angioplastia transluminal coronaria (ATC primaria son técnicas bien establecidas, sin embargo gran parte de los pacientes con infarto agudo de miocardio con supradesnivel del segmento ST (IAM con SST no las reciben cuando de la atenci

  15. PROFILAXIS DE LA NEFROPATÍA INDUCIDA POR CONTRASTE EN PACIENTES DE ALTO RIESGO CON SÍNDROME CORONARIO AGUDO SIN ELEVACIÓN DEL SEGMENTO ST / Prophylaxis of contrast-induced nephropathy in high risk patients with non-ST-segment elevation acute coronary syndrome

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    Pilar Portero Pérez; Tatiana Matajira Chia; Ramón Bascompte Claret; Pilar Artero Bello; Antonela Lukic; Jose A. Linares Vicente; Pablo Revilla Martí; Jose R. Ruiz Arroyo

    2012-01-01

    ResumenIntroducción y objetivos: La eficacia de la administración conjunta de suero salino isotónico y N-acetilcisteína presenta resultados dispares en la prevención de la nefropatía por contraste yodado. Nuestro objetivo fue valorar la posible eficacia de esta estrategia combinada en pacientes con alto riesgo de desarrollar nefropatía inducida por contraste, ingresados y sometidos a intervencionismo coronario percutáneo por síndrome coronario agudo sin elevación del segmento ST en nuestro ce...

  16. Correlación entre la localización del lente intraocular, según biomicroscopia ultrasónica,y diferentes parámetros quirúrgicos en pacientes operados de catarata Correlation between the location of the intraocular lens according to ultrasonic biomicroscopy and several surgical parameters in patients operated from cataract

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    Eneida de la C Pérez Candelaria

    2010-01-01

    Full Text Available OBJETIVO: Determinar la correlación entre la localización del lente intraocular en cámara posterior por biomicroscopia ultrasónica, diferentes parámetros quirúrgicos en pacientes operados de catarata. MÉTODOS: Se realizó un estudio descriptivo, prospectivo y transversal en el Instituto Cubano de Oftalmología «Ramón Pando Ferrer», durante el período de enero a junio del 2007. Se estudiaron variables como: edad, sexo, etiología de la catarata, técnica quirúrgica, localización del lente intraocular según biomicroscopia ultrasónica, así como complicaciones transoperatorias y posoperatorias. RESULTADOS: El 79 % de todos los pacientes operados tenían entre 60 y 79 años de edad y algo más de la mitad correspondió al sexo femenino con un 59 %. La catarata senil fue la etiología que predominó con un 74 % y en el 68 % de los casos el lente se localizó por biomicroscopia ultrasónica en el saco capsular. En los ojos donde el lente intraocular se localizó fuera del saco, la proporción de complicaciones transoperatorias y posoperatorias fueron significativamente mayoritarias, mientras que en los ojos donde el lente intraocular se encontraba en el saco, la mayoría no presentó complicaciones transoperatorias ni posoperatorias. CONCLUSIONES: Las diferencias entre las distintas localizaciones del lente intraocular se encontraron con significación estadística en el tipo de catarata, la presencia de complicaciones transoperatorias y posoperatorias, sin embargo, no se encontró relación estadística significativa entre la localización del lente intraocular con la técnica quirúrgica utilizada.OBJECTIVE: To determine the correlation between the location of the intraocular lens in the posterior chamber using ultrasonic biomicroscopy and the different surgical parameters in patients operated from cataract. METHODS: A prospective, descriptive and cross-sectional study was carried out in "Ramón Pando Ferrer" Cuban Institute of

  17. Incidencia y manejo del infarto agudo miocárdico con elevación del segmento ST, Hospital José María Velasco Ibarra, 2014

    OpenAIRE

    Gustavo Moreno Martín; César Santiago Mejía Moya; Miriam Ivonne Fernández Nieto; Rosendo Sánchez Núñez

    2016-01-01

    Introducción: El término infarto agudo de miocardio, hace referencia a un riego sanguíneo insuficiente con lesión miocárdica, producido por una obstrucción en una o varias arterias coronarias. Objetivo: Determinar la incidencia y manejo del infarto agudo miocárdico en el Hospital José María Velazco Ibarra, en el período enero a junio del 2014. Métodos: Se realizó un estudio observacional descriptivo y retrospectivo en 52 pacientes con infarto agudo miocárdico con elevación del segment...

  18. Características Cinemáticas y Condiciones de Deformación de un Segmento de la Falla Palestina al NE del Volcán Nevado del Ruíz

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    Mejía Toro, Eliana Lucía

    2012-01-01

    El propósito de este trabajo fue contribuir y mejorar el entendimiento de la geología local, regional y tectónica de la Cordillera Central, a partir del conocimiento de la cinemática de las fallas al oeste del Volcán Nevado del Ruíz (VNR), su relación con el sistema geotérmico asociado y la caracterización de fases deformativas de las rocas aflorantes en los alrededores de la Falla Palestina. Mediante la interpretación de fotografías aéreas e imágenes de satélite, en conjunción con el anális...

  19. Angiografía del día siguiente tras fibrinólisis exitosa frente al tratamiento convencional, en el síndrome coronario agudo con elevación del segmento ST, fibrinolisado

    Directory of Open Access Journals (Sweden)

    José D. Cascón-Pérez, MD

    2012-01-01

    Conclusiones: la angiografía del día siguiente se asocia con una reducción de la estancia media respecto al tratamiento convencional. Además, parece mostrar una tendencia (no significativa de reducción de mortalidad al año, sin que aumente el número de complicaciones hemorrágicas.

  20. ESTRATIFICACIÓN DEL RIESGO EN EL SÍNDROME CORONARIO AGUDO CON ELEVACIÓN DEL SEGMENTO ST / Risk stratification in acute coronary syndrome with ST-segment elevation

    Directory of Open Access Journals (Sweden)

    Luis Alberto Rodríguez López

    2010-12-01

    Full Text Available Resumen Introducción y objetivos: El tamaño del infarto y la repercusión sobre la función ventricular constituyen problemas importantes para el pronóstico del paciente. El objetivo de este trabajo fue valorar los factores de mal pronóstico antes del egreso hospitalario mediante la realización de ergometría submaximal y ecocardiograma. Material y método: Se realizó una investigación descriptiva, prospectiva, con 85 pacientes con infarto que recibieron o no terapia trombolítica, en el Hospital Universitario “Celestino Hernández Robau” de Santa Clara, a los cuales se les realizó ergometría y ecocardiograma antes del egreso para detectar variables de mal pronóstico. Resultados: Predominó el sexo masculino (82,2 %, el grupo de edad de 55 años y más (47,1 %, la hipertensión arterial (80 % y el tabaquismo (75,2 %. La localización más frecuente fue la póstero-inferior (78,8 %; la fracción de eyección del ventrículo izquierdo fue mejor en los tratados con trombolíticos, y se detectaron los que tenían una mala función ventricular (10,6 %. El 74,1 % presentó clase funcional I y se identificaron 21 pacientes (24,7 % con mal pronóstico. No hubo diferencia significativa respecto a la terapia trombolítica, pero los pacientes que la recibieron presentaron un mejor comportamiento clínico. Conclusiones: Se encontraron 31 pacientes con prueba de esfuerzo positiva, de mal pronóstico, 5 de ellos con clase funcional III, los cuales presentaron también FEVI disminuida. La prueba de esfuerzo submáxima y el ecocardiograma bidimensional constituyeron herramientas de primera línea en la valoración pronóstica del paciente con IAM, por su existencia en casi todos los centros hospitalarios, bajo costo, poco o ningún riesgo y ser fácil de realizar, y reproducir. / Abstract Introduction and Objectives: Infarct size and the effect on ventricular function are significant problems for the patient's prognosis. The aim of this study was

  1. Incidencia y manejo del infarto agudo miocárdico con elevación del segmento ST, Hospital José María Velasco Ibarra, 2014

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    Gustavo Moreno Martín

    2016-12-01

    Conclusiones: La mayor incidencia de IAMCEST fue en pacientes adultos mayores y del sexo masculino, en relación al hábito de fumar, los trastornos en el metabolismo de los lípidos, hipertensión arterial y la Diabetes Mellitus; en el caso de la diabetes mellitus que representa un factor de riesgo independiente de mortalidad en estos pacientes. Se observó un uso subóptimo de betabloqueadores e inhibidores de la enzima convertidora de angiotensina.

  2. Intraocular pathology

    International Nuclear Information System (INIS)

    Mafee, M.F.; Resnick, K.; Jampol, L.; Kaufman, L.

    1991-01-01

    This paper reports that this study was undertaken to evaluate the role of gadolinium-enhanced MR imaging in evaluating patients with intraocular pathology. In 21 patients with uveal melanomas (n = 10), melanocytoma (n = 1), choroidal hemangiomas (n = 4), bilateral uveal lymphoma (n = 1), choroidal detachment (n = 1), or retinoblastomas (n = 3), we attempted MR imaging of the eye by using a 1.5-T GE signa unit. T2-weighted images and pre- and postgadolinium T1-weighted MR images were obtained. Uveal melanomas demonstrated moderate homogeneous or inhomogeneous intensity with gadolinium enhancement. In some patients, associated hemorrhage in the subretinal space behaved identical to melanoma on T1- and T2-weighted images. In these cases, gadolinium clearly demonstrated enhancement only with the tumor. Choroidal hemangiomas, unlike melanomas, were hyperintense on T2-weighted images and demonstrated intense homogeneous enhancement on gadolinium-enhanced MR images. Retinoblastomas appeared like uveal melanomas on MR images

  3. Evaluación del espesor corneal central y su influencia en la presión intraocular en pacientes del Hospital "Dr. Miguel Enríquez" Evaluation of the central corneal thickness and its impact on the intraocular pressure of patients in "Dr. Miguel Enriquez" hospital

    Directory of Open Access Journals (Sweden)

    María Teresa Arrronte Alarcón

    2012-01-01

    Full Text Available Objetivo: evaluar el espesor corneal central en sujetos sanos, hipertensos oculares, sospechosos de glaucoma y glaucomatosos, y su influencia en la presión intraocular. Métodos: se realizó un estudio descriptivo y transversal que incluyó 708 ojos de 356 sujetos que acudieron al servicio de oftalmología del Hospital Universitario "Dr. Miguel Enríquez" entre enero y diciembre de 2010. A los pacientes se les midió el espesor corneal central con paquimetría ultrasónica (paquímetro US 4000. El resto de la información se obtuvo a partir de las historias clínicas de los pacientes. Resultados: Los hipertensos oculares presentaron córneas gruesas (p=0,07; el mayor número de casos que tenían diagnóstico de sospecha de glaucoma y de glaucoma primario de ángulo abierto presentaron un grosor corneal delgado (p=0,62 y p=0,08 respectivamente. Si no se hubiese tenido en cuenta el factor de corrección para evaluar la presión intraocular se encontraría 48,1 % de los glaucomatosos y 31,5 % de los hipertensos oculares con diagnóstico inadecuado (pObjective: to evaluate the central corneal thickness in healthy individuals, in persons with ocular hypertension, and in suspected glaucoma and glaucomatous people, and its influence in intraocular pressure. Methods: a cross-sectional and descriptive study was performed in 708 eyes from 356 people who had been seen at ophthalmology service of “Dr. Miguel Enríquez”, university hospital from January to December, 2010. Their central corneal thickness was measured with ultrasonic pachymetry (pachymeter US 4000. The rest of the information came from the clinical histories of the patients. Results: Most of the ocular hypertensives presented thick corneas (p=0,07; a high number of cases that had diagnosis of glaucoma suspicion and primary open-angle glaucoma showed thin corneas (p=0,62 and (p=0,08 respectively. If the correction factor to evaluate the IOP had not been considered, then 48,1 % of the

  4. Facoemulsificación e implante de lente intraocular en cataratas causadas por uveitis Phacoemulsification and intraocular lens implantation in patients with cataract caused by uveitis

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    Dayamí Pérez Gómez

    2008-06-01

    Full Text Available OBJETIVO: Evaluar los resultados de la facoemulsificación y el implante de lente intraocular en cataratas causadas por uveítis. MÉTODOS: Se estudiaron 37 ojos con 6 meses de inactividad inflamatoria, agudeza visual menor de 0,6 y edad media de 47 años. Se excluyeron otras enfermedades que disminuyeran la visión. En el preoperatorio se prescribió antiinflamatorios. Se realizó la facoemulsificación con implante de lente intarocular (PMMA, óptica 6 mm; durante el seguimiento desde 24 h/6 meses se indicó antiinflamatorios esteroideos, no esteroideos e inmunosupresores hasta 6 semanas. RESULTADOS: Se observaron numerosas alteraciones del segmento anterior secundarias a las uveítis padecidas (posquirúrgicas, inespecíficas, ciclítis heterocrómica de Fuchs, postraumáticas, síndrome de Reiter, por toxoplasmosis y otras coroiditis infecciosas y por artritis reumatoide juvenil. No hubo recurrencia posquirúrgica de la uveítis en 9 ojos (24,3 %. Las complicaciones estuvieron relacionadas con la uveítis, la cirugía, la actividad inflamatoria, y la reacción del epitelio capsular. La opacidad capsular posterior apareció en 11 pacientes (29,7 % asociada a edad joven. La evolución individual se consideró satisfactoria en 30 (81,1 % pacientes con mejoría de la visión hasta 0,8-1,0 en 28 (75,6 % y 0,5-0,6 en 2 (5,4 %. CONCLUSIONES: La facoemulsificación con implante de lente intarocular es de gran utilidad en las cataratas posuveítis al condicionar poca agresión quirúrgica, ser controlable la inflamación y proporcionar buenos resultados visuales además del reordenamiento anatomofisiológico del segmento anterior.OBJECTIVE: To assess the results of phacoemulsification and intraocular lens implantation in cataracts caused by uveitis. METHODS: Thirty seven eyes with no inflammation for 6 months, visual acuity below 0.6 and average age of 47 years were studied. Other diseases affecting the vision were excluded. The preoperative

  5. Estudio del entotelio corneal en la corrección de alta miopía con lente intraocular fáquica Artisan Study of the corneal endothelium in high myopia correction with Artisan phakic intraocular lens

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    Yanele Ruiz Rodríguez

    2009-06-01

    Full Text Available OBJETIVO: Identificar los efectos sobre el endotelio corneal al implantar lentes intraoculares fáquicas Artisan en la corrección de la alta miopía en el Instituto Cubano de Oftalmología "Ramón Pando Ferrer" en el período de enero de 2006 a julio de 2007. MÉTODOS: Se realizó un estudio prospectivo, descriptivo. El universo estuvo constituido por 17 ojos, a los cuales se les implantó lente intraocular fáquica Artisan para la corrección de la alta miopía. RESULTADOS: La pérdida celular endotelial fue de 4,6 % y no hubo variaciones significativas en el coeficiente de variación y la hexagonalidad. CONCLUSIONES: La pérdida celular endotelial fue baja al año de la cirugía. El coeficiente de variación y la hexagonalidad no mostraron cambios significativos.OBJECTIVE: To identify the effects on the corneal endothelium of Artisan phakic intraocular lens implantation for the high myopia correction at "Ramón Pando Ferrer" Cuban Institute of Ophthalmology from January 2006 to July 2007. METHODS: A prospective descriptive study was performed on 17 eyes which underwent Artisan phakic intraocular lens implantation for high myopia correction. RESULTS: Endotelial cell loss was 4,6% and no significant variations were found in variation coefficient and hexagonality. CONCLUSIONS: Endotelial cell loss was low after one year of surgery. The variation coefficient and hexagonality did not show any significant changes.

  6. Biocompatibility of Intraocular Lenses.

    Science.gov (United States)

    Özyol, Pelin; Özyol, Erhan; Karel, Fatih

    2017-08-01

    The performance of an intraocular lens is determined by several factors such as the surgical technique, surgical complications, intraocular lens biomaterial and design, and host reaction to the lens. The factor indicating the biocompatibility of an intraocular lens is the behavior of inflammatory and lens epithelial cells. Hence, the biocompatibility of intraocular lens materials is assessed in terms of uveal biocompatibility, based on the inflammatory foreign-body reaction of the eye against the implant, and in terms of capsular biocompatibility, determined by the relationship of the intraocular lens with residual lens epithelial cells within the capsular bag. Insufficient biocompatibility of intraocular lens materials may result in different clinical entities such as anterior capsule opacification, posterior capsule opacification, and lens epithelial cell ongrowth. Intraocular lenses are increasingly implanted much earlier in life in cases such as refractive lens exchange or pediatric intraocular lens implantation after congenital cataract surgery, and these lenses are expected to exhibit maximum performance for many decades. The materials used in intraocular lens manufacture should, therefore, ensure long-term uveal and capsular biocompatibility. In this article, we review the currently available materials used in the manufacture of intraocular lenses, especially with regard to their uveal and capsular biocompatibility, and discuss efforts to improve the biocompatibility of intraocular lenses.

  7. A prospective study demonstrating the effect of 5% povidone-iodine application for anterior segment intraocular surgery in Paraguay Estudio prospectivo demostrando el efecto de la instilación de yodo povidona al 5% previo a cirugía de segmento anterior en Paraguay

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    Lorena P. Quiroga

    2010-04-01

    Full Text Available PURPOSE: To determine the conjunctival bacterial flora in cataract surgery patients and the effect of presurgical irrigation with 5% povidone-iodine solution. METHODS: Three samples from the inferior conjunctival fornix of the eye to be operated were obtained at baseline before washing (T0 with 10 ml 5% povidone-iodine solution, immediately after washing (T1, and upon completion of surgery (T2. Bacteria from the samples were inoculated in blood agar, chocolate agar, and thioglycolate broth. RESULTS: A total of 221 patients (n=224 eyes with a mean age of 67 ± 13 years were included in the study. Bacteria from the (T0 samples were successfully grown in 73.2% of the thioglycolate agars, 21.0% of the blood agars, and 19.2% of the chocolate agars. Compared with T1 samples, the use of povidone-iodine wash translated into a 60.8% reduction (from 73.2% to 12.5% in colonization of the conjunctiva (pOBJETIVO: Determinar la flora bacteriana de la conjuntiva en los pacientes a ser sometidos a cirugía de catarata y el efecto del lavado prequirúrgico con yodo povidona al 5% sobre dichos microorganismos. MÉTODOS: Se tomaron 3 muestras del fondo de saco conjuntival del ojo a ser operado de catarata antes (T0 de la irrigación de la conjuntiva con 10 ml de yodo povidona al 5%, como control, inmediatamente después (T1 y al término de la cirugía (T2. Se realizaron cultivos en agar sangre, agar chocolate y en caldo de tioglicolato. RESULTADOS: Se incluyeron en el estudio 221 pacientes (n=24 ojos con un promedio de edad de 67 ± 13 años. El porcentaje de crecimiento bacteriano en (T0 fue de 73,2% en tioglicolato, 21% en agar sangre y 19,2 % en agar chocolate. Al compararlo con (T1 el efecto de la yodo povidona se tradujo en una reducción del 60,8% (de 73,2% a 12,5% en la colonización conjuntival (p<0.001. Entre las muestras de los tiempos T1 y T2 no hubo diferencia significativa en cuanto al crecimiento bacteriano. CONCLUSIÓN: El lavado conjuntival con

  8. Estudio y valoración de la afectación del segmento cervical en pacientes con espondilitis anquilosante : propuesta de modificación en la columna cervical del índice radiográfico utilizado para la valoración del daño estructural

    OpenAIRE

    Moreno Martínez, María José

    2016-01-01

    INTRODUCCIÓN La Espondilitis Anquilosante (EA) es una enfermedad inflamatoria predominantemente axial, cuya lesión principal es el sindesmofito ocasionando una fusión de segmentos vertebrales. Se pueden afectar todas las estructuras vertebrales, incluso las articulaciones interapofisarias (AIs). La radiología simple es la herramienta principal para valorar la progresión de la enfermedad. Ningún índice radiográfico analiza las lesiones de las AIs. El índice más ampliamente utilizado es el m...

  9. Instrumentação interespinhosa na doença degenerativa da coluna lombar: medição da altura do disco no segmento instrumentado Instrumentación interespinosa en la enfermedad degenerativa de la columna lumbar: medición de la altura del disco en el segmento instrumentado Interspinous instrumentation in patients with degenerative lumbar spine disease: disc height measurement on instrumented segment

    OpenAIRE

    José Alberto de Castro Guimarães Consciência

    2009-01-01

    INTRODUÇÃO: na última década, a instrumentação interespinhosa vem sendo mais frequentemente utilizada. Apesar dos inúmeros artigos publicados em revistas internacionais de reconhecido mérito científico, são escassas as referências à modificação da altura do disco no segmento tratado, secundária àquela instrumentação. OBJECTIVO: quantificar uma eventual modificação da altura discal decorrente da aplicação de instrumentação interespinhosa (DIAM - Cousin-Biotech - Medtronic Sofamor Danek Inc©). ...

  10. Disritmias cardíacas e alterações do segmento ST em idosos no perioperatório de ressecção transuretral da próstata sob raquianestesia: estudo comparativo Disritmias cardíacas y alteraciones del segmento ST en ancianos en el perioperatorio de resección transuretral de la próstata sobre raquianestesia: estudio comparativo Cardiac arrhythmias and ST changes in the perioperative period of elderly patients submitted to transurethral prostatectomy under spinal anesthesia: comparative study

    Directory of Open Access Journals (Sweden)

    Beatriz Lemos da Silva Mandim

    2004-04-01

    inguinal, nos períodos intra e pós-operatório.JUSTIFICATIVA Y OBJETIVOS: Ancianos representan 25% del total de los pacientes quirúrgicos. Muchos pacientes con enfermedad arterial coronariana (DAC presentan electrocardiograma (ECG pre-operatorio normal, y alta incidencia de infarto agudo del miocárdio (IAM silencioso en la 1ª semana de pos-operatorio. Las disritmias aumentan con la edad, siendo observadas extrasístoles supraventriculares (ESSV y ventriculares (ESV, fibrilación atrial y disturbios de la conducción intraventricular. El objetivo de este estudio fue evaluar la prevalencia de disritmias cardíacas y de alteraciones del segmento ST en el perioperatorio por intermedio del Holter en pacientes ancianos sometidos a cirugía de resección transuretral de la próstata (RTU y herniorrafia inguinal bajo raquianestesia. MÉTODO: Fueron evaluados 21 pacientes con edades entre 65 y 84 años, sometidos a RTU de la próstata y 16 pacientes con edades de 65 a 86 años, sometidos a herniorrafia inguinal, bajo raquianestesia. Evaluación por el Sistema Holter en el pre-operatorio (12 horas, intra-operatorio (3 horas y pos-operatorio (12 horas. RESULTADOS: La prevalencia de extrasístoles supraventriculares (ESSV entre los grupos RTU el control fue, en el pre-operatorio 85,7% vs. 93,7%, en el intra-operatorio 85,7% vs. 81,2% y en el pos operatorio de 76,2% vs. 100%. Las extrasístoles ventriculares (ESV tuvieron prevalencia de 76,2% vs. 81,2% en el pre, 80,9% vs. 68,7% en el per y 80,9% vs. 81,2% en el pos-operatorio. La prevalencia de alteraciones del segmento ST entre los grupos RTU y control fue, no pre-operatorio 19% vs. 18,7%, en el intra-operatorio 4,7% vs. 18,7% y en el pos-operatorio de 14,3% vs. 18,7%, sin significancia estadística. CONCLUSIONES: Los pacientes ancianos presentan alta prevalencia de ESSV y ESV. El número total de ESSV y ESV, y alteraciones del segmento ST, presentes en el período pre-operatorio, no fue alterado por la cirugía de resecci

  11. El NT-pro BNP predice mal pronóstico en pacientes con síndromes coronarios agudos sin elevación del segmento ST y función ventricular conservada

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    Florencia Rolandi

    2006-01-01

    Full Text Available Antecedentes El NT-proBNP se asocia con disfunción ventricular y mala evolución en síndromes coronarios agudos sin elevación del ST (SCA-SEST. La evidencia sobre su valor pronóstico en pacientes con SCA-SEST y función sistólica conservada es escasa. Objetivos Explorar el valor pronóstico del NT-proBNP en pacientes con SCA-SEST sin disfunción ventricular. Material y métodos De una cohorte de pacientes con SCA-SEST sometidos a angiografía se seleccionaron 393 con fracción de eyección del ventrículo izquierdo =?40%. Laboratorios centrales independientes analizaron las angiografías y las determinaciones de NT-proBNP, troponina T, mioglobina y proteína C reactiva. Se empleó un punto de corte de NT-proBNP de 586 pg/ml El punto final primario fue la incidencia de muerte o infarto a los 180 días. Resultados Ochenta y tres pacientes (21% tuvieron NT-proBNP =?586 pg/ml y 310 (79% niveles < 586 pg/ml. Los pacientes con NT-proBNP elevado eran más añosos, con mayor frecuencia de sexo femenino; tuvieron una proporción mayor de marcadores séricos elevados y una proporción mayor de enfermedad coronaria extensa y de lesiones coronarias complejas. Estos pacientes, comparados con aquellos con NT-proBNP < 586 pg/ml, tuvieron una incidencia mayor de muerte (9,6% versus 2,3%; p = 0,002, infarto (9,6% versus 3,2%; p = 0,01 y muerte o infarto (16,9% versus 5,5%; p = 0,001 a los 180 días. Ajustando por variables clínicas, electrocardiográficas y angiográficas, el NT-proBNP resultó ser un predictor independiente del punto final combinado de muerte o infarto a los 6 meses y de muerte por cualquier causa. Conclusiones El NT-proBNP es un predictor independiente de muerte e infarto y de muerte global a los 6 meses en pacientes con SCA-SEST sin disfunción ventricular.

  12. Instrumentação interespinhosa na doença degenerativa da coluna lombar: medição da altura do disco no segmento instrumentado Instrumentación interespinosa en la enfermedad degenerativa de la columna lumbar: medición de la altura del disco en el segmento instrumentado Interspinous instrumentation in patients with degenerative lumbar spine disease: disc height measurement on instrumented segment

    Directory of Open Access Journals (Sweden)

    José Alberto de Castro Guimarães Consciência

    2009-09-01

    Full Text Available INTRODUÇÃO: na última década, a instrumentação interespinhosa vem sendo mais frequentemente utilizada. Apesar dos inúmeros artigos publicados em revistas internacionais de reconhecido mérito científico, são escassas as referências à modificação da altura do disco no segmento tratado, secundária àquela instrumentação. OBJECTIVO: quantificar uma eventual modificação da altura discal decorrente da aplicação de instrumentação interespinhosa (DIAM - Cousin-Biotech - Medtronic Sofamor Danek Inc©. MÉTODOS: o autor avalia um grupo de 20 pacientes com patologia degenerativa da coluna lombar e os seguintes critérios de inclusão: idade >40 e 6; Oswestry Disability Index (ODI >30; Zung Depression Rating Scale INTRODUCCIÓN: la instrumentación interespinosa tiene sido empleada con creciente frecuencia en la última década. Pero, apesar de las numerosas publicaciones científicas hechas en jornales científicos de reconocido mérito internacional, se han producido muy escasas referencias a una hipotética modificación de la altura discal dependiente de la técnica. OBJETIVO: cuantificar una eventual modificación de la altura discal inherente a la aplicación de instrumentación interespinosa. MÉTODOS: el autor hace una evaluación de un grupo de 20 pacientes con patología degenerativa de la columna lumbar, y diversos criterios de inclusión, a saber: edad >40 y 6; Oswestry Disability Index >30; Zung Depression Rating Scale INTRODUCTION: the use of interspinous instrumentation has been increasing in the last decade. However, in spite of the numerous papers seen in relevant scientific publications, there are very few references to an eventual disc height variation in the instrumented segment. OBJECTIVE: to certify eventual changes in disk height after interspinous instrumentation (DIAM - Cousin-Biotech - Medtronic Sofamor Danek Inc©. METHODS: the author evaluated 20 patients with degenerative lumbar disease and the following

  13. PROFILAXIS DE LA NEFROPATÍA INDUCIDA POR CONTRASTE EN PACIENTES DE ALTO RIESGO CON SÍNDROME CORONARIO AGUDO SIN ELEVACIÓN DEL SEGMENTO ST / Prophylaxis of contrast-induced nephropathy in high risk patients with non-ST-segment elevation acute coronary syndrome

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    Pilar Portero Pérez

    2012-07-01

    Full Text Available ResumenIntroducción y objetivos: La eficacia de la administración conjunta de suero salino isotónico y N-acetilcisteína presenta resultados dispares en la prevención de la nefropatía por contraste yodado. Nuestro objetivo fue valorar la posible eficacia de esta estrategia combinada en pacientes con alto riesgo de desarrollar nefropatía inducida por contraste, ingresados y sometidos a intervencionismo coronario percutáneo por síndrome coronario agudo sin elevación del segmento ST en nuestro centro. Método: Se aplicó esta estrategia en los pacientes referidos, con al menos un factor de alto riesgo para desarrollar la nefropatía inducida por contraste: mayores de 80 años, diabetes mellitus, creatinina basal mayor de 1,5 mg/dl o alto volumen de contraste (mayor de 400 ml. El protocolo se aplicó durante 12 meses (pacientes que recibieron el protocolo de prevención y se comparó con similares pacientes en los 12 meses previos que no recibieron profilaxis. Resultados: Un total de 30 pacientes (24 % desarrollaron nefropatía inducida por contraste. El porcentaje fue significativamente mayor en el grupo que no recibió profilaxis: 35,9 % vs. 11,5 % (p = 0.003. Conclusiones: La combinación de N-acetilcisteína por vía oral e hidratación parenteral en pacientes de alto riesgo, con síndrome coronario agudo sin elevación de ST, podría ser beneficiosa para evitar la aparición de la nefropatía inducida por contraste. /Abstract Introduction and Objectives: The effectiveness of the administration of isotonic saline solution and N-acetylcysteine shows different results in the prevention of iodine contrast nephropathy. Our objective was to assess the potential effectiveness of this combined strategy in patients at high risk for contrast-induced nephropathy, who were admitted in our center for percutaneous coronary intervention due to non-ST-segment elevation acute coronary syndrome. Method: This strategy was applied in the patients

  14. Resultados del implante múltiple de lentes intraoculares en la cirugía de catarata en el Instituto Cubano de Oftalmología "Ramón Pando Ferrer" Results of the multiple intraocular lenses implantation in the cataract surgery performed at "Ramón Pando Ferrer" Cuban Institute of Ophthalmology

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    Eric Montero Díaz

    2010-06-01

    Full Text Available OBJETIVO: Valorar los resultados visuales de los pacientes operados con la técnica de piggy back o implantes múltiples de lentes intraoculares. MÉTODOS: Se realizó un estudio descriptivo retrospectivo de corte transversal en el que se tomaron 32 ojos de 30 pacientes del universo operado de catarata, con la técnica antes descrita, en el Instituto Cubano de Oftalmología "Ramón Pando Ferrer", en el período comprendido entre enero de 2000 hasta diciembre de 2006. Fueron evaluadas algunas variables demográficas, como edad y sexo, así como agudeza visual y refracción preoperatorio y posoperatoria con cristales y sin ellos. Reportamos las complicaciones transquirúrgicas y posquirúrgicas asociadas a las diferentes técnicas quirúrgicas empleadas para la extracción del cristalino. RESULTADOS: La edad promedio obtenida fue mayor de 50 años, y predominó el sexo femenino. Parte de los pacientes tuvieron una agudeza visual corregida superior a 20/40. La complicación más frecuente fue la opacidad de la cápsula posterior y solo en la tercera parte de los pacientes se obtuvo una buena corrección refractiva. CONCLUSIONES: La técnica de piggy back permitió la recuperación de cuatro líneas en la cartilla de Snellen en la agudeza visual corregida, mientras que en la agudeza visual sin corrección solo aumentó en dos líneas. Se encontró igual número de pacientes hipocorregidos y bien corregidos.OBJECTIVE: To asses the visual results of patients operated on by piggy back technique or multiple implantation of intraocular lenses METHODS: A retrospective cross-sectional descriptive study was conducted in 32 eyes from 30 patients operated on from cataract, using the above-mentioned technique, at "Ramon Pando Ferrer" Cuban Institute of Ophthalmology in the period January 2000 through December 2006. Some demographic variables as age and sex as well as visual acuity and preoperative and postoperative refraction with/without lenses were evaluated

  15. Variación de los segmentos corporales en niños de diferentes contextos socioeconómicos de Puerto Madryn, Chubut

    Directory of Open Access Journals (Sweden)

    Peralta, Lorena

    2003-01-01

    Full Text Available Existe evidencia que la alteración diferencial de los segmentos corporales es el resultado de factores estresantes reflejando en el crecimiento de los individuos, la calidad de vida de la población. El objetivo del presente trabajo es evaluar el efecto del nivel socioeconómico (NSE sobre la variación de los segmentos corporales de una muestra de escolares de la EGB de cinco colegios de la ciudad de Puerto Madryn. La muestra se integró con 897 escolares (6-14 años de ambos sexos pertenecientes a dos NSE. Se relevaron la estatura total, la estatura sentada y se calculó el índice córmico. Los datos fueron expresados como puntajes Z mediante la comparación con la referencia NHANES I y II. El procesamiento estadístico consistió en ANOVA, con un nivel de significación del 5%. Los resultados obtenidos indicaron que en ambos sexos la talla media del NSE2 presentó diferencias significativas respecto a la referencia, en tanto que el NSE1 no mostró variación. En cuanto a las otras dos variables estudiadas las diferencias fueron no significativas en ambos grupos. Al comparar ambos grupos socioeconómicos entre sí se observó mayor talla entre los niños y niñas pertenecientes al NSE1 mientras que el índice córmico es mayor en los niños y niñas del NSE2. Se concluye que la variación observada en los segmentos corporales corresponde a una alteración del patrón de crecimiento normal del segmento inferior, generalmente encontrada en poblaciones deprimidas económicamente.

  16. Avaliação de corpos estranhos no segmento anterior com ultrassonografia biomicroscópica

    Directory of Open Access Journals (Sweden)

    Marília Freitas de Moura

    2012-04-01

    Full Text Available INTRODUÇÃO: O traumatismo ocular é a causa mais importante de perda visual no mundo, sendo um problema de saúde pública. Os corpos estranhos intraoculares são relacionados a atividades que envolvem manuseio de objetos metálicos, porém outros materiais podem estar presentes, e devem ser diagnosticados e localizados no olho. A ultrassonografia biomicroscópica é uma ferramenta complementar adequada para avaliar um corpo estranho do segmento anterior do olho. OBJETIVO: Caracterizar a natureza, localização, dimensões de corpos estranhos e lesões associadas ao segmento anterior, utilizando-se ultrassonografia biomicroscópica. MÉTODO: Estudo clínico retrospectivo, por meio da análise de 7.182 prontuários dos anos de 1999 a 2008, com 59 exames de pacientes com suspeita de corpo estranho no segmento anterior ocular. RESULTADOS: Dentre os 59 exames, confirmou-se pela ultrassonografia biomicroscópica a presença de corpo estranho no segmento anterior em 42 (71,19% olhos de 42 pacientes. A idade dos pacientes variou entre 9 e 76 anos (média= 37,4 anos. Houve predominância do sexo masculino (85,71%. Cinco casos apresentaram dois corpos estranhos, fragmentos da mesma natureza, em diversas localizações ou não; e três casos continham incontáveis fragmentos dispostos no segmento anterior. Considerando sua localização: córnea, 11 (26%; conjuntiva, 10 (23%; íris, 10 (23%; cristalino, 9 (21%; esclera, 5 (12%; seio camerular, 5 (12%; corpo ciliar, 3 (7%. Dentre as lesões associadas, identificou-se: perfuração corneana em 12 casos, laceração corneana em 2 casos, sinéquia anterior em 6 casos, aniridia traumática em 1 caso, iridotomia traumática em 3 casos, reação de câmara anterior em 10 casos e rotura de cápsula anterior do cristalino em 4 casos. Considerando a composição: metálicos, 21 (50%; não-metálicos, 20 de vidro (48% e 1 de origem vegetal (2%. O tamanho dos corpos estranhos variou de 0,09 a 2,45 mm (média: 0

  17. Intraocular pressure reduction and regulation system

    Science.gov (United States)

    Baehr, E. F.; Burnett, J. E.; Felder, S. F.; Mcgannon, W. J.

    1979-01-01

    An intraocular pressure reduction and regulation system is described and data are presented covering performance in: (1) reducing intraocular pressure to a preselected value, (2) maintaining a set minimum intraocular pressure, and (3) reducing the dynamic increases in intraocular pressure resulting from external loads applied to the eye.

  18. MRI findings of intraocular diseases

    Energy Technology Data Exchange (ETDEWEB)

    Takeda, Makoto; Nagai, Haruhiko; Ueno, Tetsuji; Igarashi, Yasuo (Sapporo Medical Coll. (Japan)); Narazaki, Yoshikazu; Takeda, Akira

    1989-06-01

    MRI findings of intra-ocular lesion were studied on seven cases : two cases of choroidal malignant melanoma, one case of choroidal tumor, two cases of retinal detachment with vitreous hemorrhage, and two cases of choroidal detachment. Intraocular lesions were clearly visualized by T{sub 1} weighted MRI which was of great benefit in visualizing morphological changes. T{sub 2} weighted images could not visualize morphological changes very well, but had some merits in differentiating the ocular pathology. MRI was a very useful examination for intra-ocular lesions. (author).

  19. MRI findings of intraocular diseases

    International Nuclear Information System (INIS)

    Takeda, Makoto; Nagai, Haruhiko; Ueno, Tetsuji; Igarashi, Yasuo; Narazaki, Yoshikazu; Takeda, Akira.

    1989-01-01

    MRI findings of intra-ocular lesion were studied on seven cases : two cases of choroidal malignant melanoma, one case of choroidal tumor, two cases of retinal detachment with vitreous hemorrhage, and two cases of choroidal detachment. Intraocular lesions were clearly visualized by T 1 weighted MRI which was of great benefit in visualizing morphological changes. T 2 weighted images could not visualize morphological changes very well, but had some merits in differentiating the ocular pathology. MRI was a very useful examination for intra-ocular lesions. (author)

  20. Angiografía del día siguiente tras fibrinólisis exitosa frente al tratamiento convencional, en el síndrome coronario agudo con elevación del segmento ST, fibrinolisado Angiography performed the next day after successful thrombolysis versus conventional treatment in acute coronary syndrome with ST segment elevation

    Directory of Open Access Journals (Sweden)

    José D Cascón-Pérez

    2012-01-01

    Full Text Available Introducción y objetivos: la incorporación de las nuevas guías de actuación de la Sociedad Europea de Cardiología en el síndrome coronario agudo, con coronariografía precoz (24 horas tras trombólisis, incluso si es efectiva y sin necesidad de demostrar signos de isquemia residual, en los casos en los que no se realiza angioplastia primaria, ha supuesto un reto respecto a la forma tradicional de actuar en los Servicios de Cardiología. Métodos: durante 2007, 2008 y la primera mitad de 2009 se atendieron 266 pacientes con infarto agudo del miocardio con ST elevado tratados con trombólisis. De ellos, y tras excluir los rescates (41, en 94 (42% se realizó cateterismo dentro de las primeras 24 horas (angiografía del día siguiente y en los 131 (58% restantes se siguió una estrategia convencional con test de provocación de isquemia (tratamiento convencional. Resultados: en el primer grupo, la estancia media fue de 7,3 ± 3 días [mediana, rango intercuantílico: 7 (5-8]. La incidencia de eventos mortales al año fue de 3 (4%. No hubo ningún sangrado mayor; sólo 20 de ellos (22% presentaron hematomas inguinales mayores de 2 cm. En el segundo, la estancia media fue de 10,2 ± 6,3 días [9 (6-13], significativamente mayor (pIntroduction and objectives: The introduction of new practice guidelines of the European Society of Cardiology in acute coronary syndrome with early coronary angiography (24 hours after thrombolysis, even if it is effective without showing signs of residual ischemia in the cases where primary angioplasty is not performed, has been a challenge over the traditional approach in the Departments of Cardiology. Methods: During 2007, 2008 and the first half of 2009, 266 patients with acute myocardial infarction with ST segment elevation were treated with thrombolysis. After excluding the bailouts (41, in 94 (42% of them, a catheterization was peformed within the first 24 hours (next day angiography and the remaining 131 (58

  1. Organogênese do caquizeiro a partir de segmentos radiculares

    Directory of Open Access Journals (Sweden)

    Carvalho Dayse Cristina de

    2004-01-01

    Full Text Available A produção de mudas de caquizeiro (Diospyros kaki pelo processo da enxertia sobre porta-enxertos provenientes de sementes, ocasiona problemas de desuniformidade vegetativa. O objetivo do trabalho foi contribuir para o desenvolvimento de um protocolo para a regeneração de brotações de caquizeiro do tipo café, a partir de raízes por organogênese indireta. Segmentos radiculares obtidos de embriões germinados in vitro foram isolados de sementes de frutos maduros em meio MSfraction one-halfNO3. As sementes receberam assepsia pela imersão em etanol 70% por um minuto, em solução de hipoclorito de sódio 2,5% por 20 minutos e quatro lavagens em água esterilizada. No primeiro experimento, os segmentos radiculares de 2cm foram isolados em meio de cultura MSfraction one-halfNO3 acrescido de 0,01mM de ácido indolacético e quatro tipos de citocininas nas concentrações 1 e 10mM: zeatina, 6-benzilaminopurina, 2-isopenteniladenina e thidiazuron. No segundo experimento, para o enraizamento das brotações, foram testados quatro períodos de permanência em meio com 10mM de ácido indolbutírico: 0, 5 10 e 15 dias. A maior regeneração de brotos (1,2 brotos por explante ocorreu na combinação 1mM de zeatina com 0,01mM de ácido indolacético. As brotações juvenis obtidas possuem potencial natural para o enraizamento, sendo necessário novos estudos para confirmar o efeito da aplicação de auxinas.

  2. Variación de los segmentos corporales de escolares patagónicos en barrios con diferentes NBB

    Directory of Open Access Journals (Sweden)

    Botterón, Tania Vanesa

    2007-01-01

    Full Text Available Los segmentos corporales presentan diferentes períodos de maduración, reflejando su relación con la nutrición y condicionando la expresión del dimorfismo sexual (DS. El objetivo del trabajo fue evaluar el DS observado en el crecimiento de escolares de 6 a 14 años de barrios con diferentes NBI -(NBI alto y (NBI bajo-. Se estudió transversalmente una muestra de 500 mujeres y 570 varones de la ciudad de Puerto Madryn, Chubut. Se relevaron: estatura total, estatura sentada (ES y se calculó la longitud del segmento inferior (LSI y el índice córmico (IC. Se utilizaron pruebas de Wilcoxon, p= 0.05. La ES presentó para todas las edades valores nominales mayores en el NBI bajo (p=0.3 respecto al NBI alto (p=0.22. De igual manera se comportó la LSI (p=0.06 NBI bajo; (p=0.09 NBI alto. El IC presentó dos eventos evidentes en cada sexo: uno cercano a los 6.5 años y hasta alrededor de los 9-10 años, donde el valor del IC fue menor en las mujeres respecto de los varones y otro a los 10.5-12 años, edad a la cual los valores femeninos superaron a los masculinos (NBI bajo p=0.16; NBI alto p=0.22. La ref. NHANES presentó un comportamiento similar. Los resultados confirman la influencia que ejercen las desigualdades sociales -como agentes estresantes- sobre el crecimiento de la población infantil estudiada, cuya respuesta adaptativa difiere a la de otras poblaciones argentinas y americanas.

  3. Criterios de diferenciación de segmentos de predisposición tecnológica en el ámbito hospitalario público

    Directory of Open Access Journals (Sweden)

    M. Teresa Martín Fuentes

    2005-01-01

    Full Text Available Investigaciones previas confirman que la estructura de segmentos identificada por Parasuraman y Colby (2001,en cuanto a grado de predisposicióntecnológica se refiere, se mantiene en elámbito hospitalario del Servicio Andaluz deSalud. En este artículo se identifican, demanera exploratoria, las variables decaracterización de la muestra que ayudan enmayor medida a predecir la pertenencia a losdistintos segmentos.A partir de un análisis de segmentaciónjerárquica, se comprueba que losconocimientos informáticos, categoríaprofesional, número de miembros delagregado familiar y el sexo, marcandiferencias en la caracterización de lossegmentos desde el punto de vista socio-laboral.

  4. [Intraocular osteosarcoma in a dog].

    Science.gov (United States)

    Wiesner, L; Schröder, S; Gralla, S; Goeck, D; Kramer, M; Ondreka, N

    2014-01-01

    The present case describes the diagnostic and therapeutic procedure of a dog with an intraocular osteosarcoma. According to the results of the diagnostic imaging studies, the tentative diagnosis of an intraocular neoplasm with perforation of the globe and orbital invasion of the tumour was made and an orbital exenteration was performed. The histopathological diagnosis of the extracted organ implied an intraocular, extraskeletal osteosarcoma. Seventy-seven days later the patient displayed an acute paraparesis. Clinical and diagnostic reevaluation using magnetic resonance imaging (MRI) was performed and the dog was euthanized at the owner's request. By means of MRI and necropsy, an additional axial osteosarcoma of the 6th lumbar vertebra and a malignant melanoma of the right tonsil were diagnosed.

  5. 21 CFR 886.4270 - Intraocular gas.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Intraocular gas. 886.4270 Section 886.4270 Food... DEVICES OPHTHALMIC DEVICES Surgical Devices § 886.4270 Intraocular gas. (a) Identification. An intraocular gas is a device consisting of a gaseous fluid intended to be introduced into the eye to place pressure...

  6. Stages of Intraocular (Uveal) Melanoma

    Science.gov (United States)

    ... or tans poorly. Blue or green or other light-colored eyes. Older age. Being white. Signs of intraocular melanoma include blurred vision ... to treat small tumors. This is also called light coagulation. ... are being tested in clinical trials. Information about clinical trials ...

  7. Estudio de la difusión intraocular y desarrollo de un nuevo sistema de medida

    OpenAIRE

    Pérez Sánchez, Guillermo M

    2009-01-01

    La descripción del ojo como un sistema óptico implica la caracterización de los fenómenos que condicionan la calidad de la imagen retiniana: las aberraciones y la difusión intraocular. El desarrollo de diferentes sistemas para evaluar las aberraciones oculares ha permitido avanzar en la descripción de la óptica del ojo. Sin embargo, los métodos para estimar la difusión intraocular no se han desarrollado de la misma manera. En este trabajo se propone una nueva metodología para estimar la difus...

  8. MRI and intraocular tamponade media

    Energy Technology Data Exchange (ETDEWEB)

    Manfre, I. (Dept. of Neuroradiology, Inst. of Neurosurgery, Univ. of Catania (Italy)); Fabbri, G. (Dept. of Neuroradiology, Inst. of Neurosurgery, Univ. of Catania (Italy)); Avitabile, T. (Inst. of Ophthalmology, Univ. of Catania (Italy)); Biondi, P. (Inst. of Ophthalmology, Univ. of Catania (Italy)); Reibaldi, A. (Inst. of Ophthalmology, Univ. of Catania (Italy)); Pero, G. (Dept. of Neuroradiology, Inst. of Neurosurgery, Univ. of Catania (Italy))

    1993-05-01

    Thirteen patients who underwent surgery for retinal detachment and injection of intraocular tamponade media (silicone oil, flurosilicone oil, or perfluoro-carbon liquid) underwent magnetic resonance imaging (MRI), using spin-echo T1- and T2-weighted images. The ophthalmic tamponade media showed different signal intensity, according to their chemical structure. Unlike ophthalmoscopy or ultrasonography, MRI showed no oil-related artefact, making possible recognition of recurrent retinal detachment. (orig.)

  9. MRI and intraocular tamponade media

    International Nuclear Information System (INIS)

    Manfre, I.; Fabbri, G.; Avitabile, T.; Biondi, P.; Reibaldi, A.; Pero, G.

    1993-01-01

    Thirteen patients who underwent surgery for retinal detachment and injection of intraocular tamponade media (silicone oil, flurosilicone oil, or perfluoro-carbon liquid) underwent magnetic resonance imaging (MRI), using spin-echo T1- and T2-weighted images. The ophthalmic tamponade media showed different signal intensity, according to their chemical structure. Unlike ophthalmoscopy or ultrasonography, MRI showed no oil-related artefact, making possible recognition of recurrent retinal detachment. (orig.)

  10. Características clínicas, angiográficas y desenlaces clínicos en adultos mayores de 65 años con síndrome coronario agudo sin elevación del segmento ST

    Directory of Open Access Journals (Sweden)

    James Díaz

    2017-09-01

    Discusión: Los pacientes de edad mayor con síndrome coronario agudo sin elevación del ST tienen características similares a las reportadas en publicaciones de otras latitudes. Sin embargo, a diferencia de lo reportado en la literatura internacional no se logró demostrar que la edad mayor a 65 años constituya un factor de riesgo independiente para desenlaces clínicos adversos en esta población.

  11. Cambios en los procedimientos diagnósticos y en el pronóstico producidos por la introducción de la troponina de alta sensibilidad en el paciente con dolor torácico agudo sin elevación del segmento ST en el electrocardiograma

    OpenAIRE

    Abellán Tejada, Lidia

    2014-01-01

    La troponina cardiaca continúa siendo un marcador de necrosis miocárdica determinante para la toma de decisiones diagnósticas y terapéuticas en pacientes con Síndrome Coronario Agudo (SCA) sin elevación del ST. La aparición de métodos de detección de troponina cardiaca de alta sensibilidad ha permitido la medida de concentraciones mínimas de troponina con una imprecisión analítica

  12. Photodynamic therapy of intraocular cancers

    International Nuclear Information System (INIS)

    Gravier, N.; Duvournau, Y.; Querec, M.A.; Pechereau, A.; Patrice, T.

    1992-01-01

    The most common intraocular tumors are choroidal malignant melanomas (70%) and retinoblastomas (13%). Each time that visual acuity is preserved, various conservative treatments are considered relative to the potential risk of metastatic disease during enucleation. In addition to standard techniques, photodynamic therapy is a potentially attractive new approach limited in its effects to the area of the treated tumor. The purpose of this preclinical study is to determine a reference dose-effect for single laser doses and to study effects of fractionation of the laser dose. (author). 9 refs., 1 tab

  13. MICROPROPAGACIÓN DE CUATRO CULTIVARES DE ARÁNDANO (Vaccinium spp. A PARTIR DE SEGMENTOS FOLIARES DE DOS PROCEDENCIAS

    Directory of Open Access Journals (Sweden)

    Arturo Brenes Angulo

    2015-01-01

    Full Text Available Los cultivares de arándano Sharpblue, Woodard, Bonita y Delite se propagaron a partir de secciones de hoja procedentes de explantes uninodales establecidos in vitro y de secciones de hoja directamente del campo. Los explantes se colocaron en medio WPM suplementado con 1, 5 mg.l -1 de TDZ para promover la brotación; luego se subcultivaron a medio fresco WPM suplementado con 0,5 ó 1,0 mg.l -1 de Zeatina, para promover el crecimiento de los brotes. Se determinó la longitud de la micromacolla y el número de brotes >2mm y >1cm por microma - colla. Brotes de 8-10 cm se cosecharon a las 8 semanas y se subcultivaron en WPM suple - mentado con 0, 1, 2, 4 u 8 mg.l -1 de AIB, para promover su enraizamiento; a las 10 semanas se trasplantaron a invernadero para aclimatización. Al cultivar los segmentos foliares en WPM con 1, 5 mg.l -1 de TDZ se formaron micromacollas en todas las variedades, independientemente de la procedencia de la hoja, con un efecto significati - vo del cultivar, la procedencia, del explante y la interacción cultivar x procedencia, para el núme - ro de brotes >2 mm obtenidos. El tamaño de la micromacolla varió significativamente según cultivares, procedencia del explante e interacción cultivares x procedencia x concentración de zea - tina, al trasferirse a un medio con 2 concentracio - nes del regulador de crecimiento, pero no hubo diferencias con respecto a éstas. El número de brotes > 2mm y la longitud del más largo variaron significativamente con el cultivar, y la interacción cultivar x procedencia del explante en WPM con 0,5 mg.l -1 de Zeatina. Explantes de Woodard a partir de vitrohoja produjeron el mayor número de brotes (44,70±13,34 y Delite de vitrohoja el menor (21,50±4,99. Los brotes subcultivados en WPM con diferentes concentraciones de AIB mostraron enraizamiento menor al 10% en todos los tratamientos. Sin embargo, al trasplantarse a invernadero se obtuvo 100% de enraizamiento, independientemente del

  14. Estrategias de reperfusión usadas en pacientes con síndrome coronario agudo con elevación persistente del segmento ST en un hospital general: Reperfusion strategies in patients with acute coronary syndrome and persistent ST-segment elevation in a general hospital

    Directory of Open Access Journals (Sweden)

    Luis Borda-Velásquez

    2015-01-01

    Full Text Available Objetivos: Conocer las estrategias de reperfusión en pacientes con síndrome coronario agudo ST elevado (SCASTE atendidos en el departamento de emergencia de un hospital general, y determinar el tiempo para realizar dichas estrategias a través de los tiempos puerta-aguja (P-A, puerta-balón (P-B, electrocardiograma (ECG y total de isquemia. Material y métodos: Estudio retrospectivo transversal en pacientes con diagnóstico de SCASTE en el Hospital Nacional Cayetano Heredia (HNCH desde el 1° de enero de 2011 al 31 de enero de 2013. Se registraron las características demográficas y clínicas, tiempos de reperfusión miocárdica, de síntomas, para toma de ECG. Los factores asociados fueron analizados por análisis bivariado. Resultados: Cuarenta y cinco pacientes fueron elegibles. La edad media fue 60,5 ± 10,98 años, 88,8% fueron varones. El tiempo medio de hospitalización fue 9,79 ± 10,36 días. Se encontró obesidad (IMC ≥ 30 en 61,3%; hipertensión en 40,9%: tabaquismo en 43,1%; y diabetes mellitus II (DM II en 25%. El tiempo medio P-A de 57 ± 54,1 minutos; en 28,1% se administró el agente trombolítico antes de los 30 minutos. Angioplastia fue realizada en un paciente con un tiempo P-B de 440 minutos. El tiempo total de isquemia (TTI medio fue 244 ± 143,9 minutos. Conclusiones: Las estrategias de reperfusión fueron usadas en 71,1% de pacientes, siendo trombólisis la más usada; sin embargo, el tiempo P-A se encontró fuera del rango óptimo

  15. Intraocular pressure estimation using proper orthogonal decomposition

    CSIR Research Space (South Africa)

    Botha, N

    2012-07-01

    Full Text Available Glaucoma is the second leading cause of irreversible blindness. The primary indicator for glaucoma is an elevated intraocular pressure, which is estimated by means of contact or non-contact tonometry. However, these techniques do not accurately...

  16. Necrotic intraocular retinoblastoma associated with orbital cellulitis.

    Science.gov (United States)

    Nalcı, Hilal; Gündüz, Kaan; Erden, Esra

    Orbital cellulitis associated with retinoblastoma is uncommon and is characterized by noninfectious inflammation of the periorbital structures. The underlying mechanism is thought to be necrosis of the intraocular tumor, leading to intraocular and periorbital inflammation. We report 2 retinoblastoma patients who presented with an orbital cellulitis-like picture and discuss clinical characteristics, histopathologic features, and treatment. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Intraocular cilia associated with perforating injury

    Directory of Open Access Journals (Sweden)

    Gopal Lingam

    2000-01-01

    Full Text Available Purpose: To report a case series of penetrating injury complicated by occurrence of intraocular cilia. Methods: Retrospective analysis of charts of 11 eyes of 11 patients with penetrating injury and intraocular cilia, presenting between September 1978 and November 1998. Ten eyes underwent surgery for trauma-related problems such as cataract, vitritis, retinal detachment etc., at which time intraocular cilia were removed. One eye did not have surgery and continues to harbour cilia at the posterior perforation site. Results: Metallic wire was responsible for injury in 6 of 11 eyes with intraocular cilia. Five eyes had significant intraocular inflammation. The cilia were located in the anterior segment in 4 eyes; in the posterior segment in 6 eyes and in both in one eye. At the last follow up, 72.7% had 6/18 or better vision. Poor vision in the rest was due to recurrent retinal detachment (2 eyes and macular scarring (1 eye. Conclusion: Intraocular cilia are more commonly associated with injury by a metallic wire. The presentation and management of an injured eye does not seem to be influenced by the presence of cilia in the eye.

  18. MR imaging of intraocular hemorrhage

    International Nuclear Information System (INIS)

    Saint-Louis, L.A.; Weiss, R.; Ellsworth, R.; Chang, S.; Deck, M.D.F.

    1987-01-01

    The authors evaluated with MR imaging 11 globes (nine patients) with spontaneous or traumatic intraocular hemorrhage. Subretinal blood was present in eight. Intravitreal bleeding was associated in seven and three subchoroidal. The ages of the hemorrhages ranged from 1 day to 6 months. Six of the subretinal and two subchoroidal cases had clotted blood with different intensity on the short TE images but were markedly hypointense on long TR/long TE images. The intravitreal blood was hyperintense on all sequences except in one. All imaging was performed with .5 T, 256 matrix, and 4- and 7- mm section thickness. Because of the varied appearance of hemorrhages, the authors scanned and are scanning two rabbits with intravitreal blood in vivo. Parameters include: 3-mm sections, T1, PD, T2 scans in .3-T and 1.5-T imagers. Initial results for the first 2 days show no change in signal intensity (hyperintense on all sequences). The T1 images show a diminishing intensity up to 8 days, and T2 scans remained hyperintense. These results so far correlate with the patient findings. The authors present the clinical findings and experimental correlation

  19. Biopsy techniques for intraocular tumors

    Directory of Open Access Journals (Sweden)

    Pukhraj Rishi

    2016-01-01

    Full Text Available Biopsy involves the surgical removal of a tissue specimen for histopathologic evaluation. Most intraocular tumors are reliably diagnosed based on the clinical evaluation or with noninvasive diagnostic techniques. However, accurately diagnosing a small percentage of tumors can be challenging. A tissue biopsy is thus needed to establish a definitive diagnosis and plan the requisite treatment. From fine-needle aspiration biopsy (FNAB to surgical excision, all tissue collection techniques have been studied in the literature. Each technique has its indications and limitations. FNAB has been reported to provide for 88-95% reliable and safe ophthalmic tumor diagnosis and has gained popularity for prognostic purposes and providing eye conserving treatment surgeries. The technique and instrumentation for biopsy vary depending upon the tissue involved (retina, choroid, subretinal space, vitreous, and aqueous, suspected diagnosis, size, location, associated retinal detachment, and clarity of the media. The cytopathologist confers a very important role in diagnosis and their assistance plays a key role in managing and planning the treatment for malignancies.

  20. Sistemas de transporte de drogas para o segmento posterior do olho: bases fundamentais e aplicações Drug delivery systems for the posterior segment of the eye: fundamental basis and applications

    Directory of Open Access Journals (Sweden)

    Sílvia Ligório Fialho

    2007-02-01

    Full Text Available As doenças do segmento posterior do olho são responsáveis pela maioria dos casos de cegueira irreversível no mundo inteiro. Este cenário estimula o desenvolvimento de novas modalidades de tratamento para estas doenças. O sucesso no tratamento visa, essencialmente, o transporte de doses efetivas de drogas diretamente para os locais a serem tratados. Devido às dificuldades encontradas no transporte de drogas para o segmento posterior do olho, pesquisas têm sido realizadas no sentido de desenvolver sistemas de administração intra-oculares que permitam liberar concentrações terapêuticas das drogas por período prolongado. Tais sistemas podem proporcionar inúmeras vantagens, como: aumentar a biodisponibilidade e a concentração local da droga, atingir especificamente um tipo de tecido ou célula, reduzir a freqüência de injeções intra-oculares. Tais vantagens podem aumentar o conforto do paciente e reduzir as complicações observadas com a utilização das injeções intra-oculares. Diferentes sistemas de transporte de drogas têm sido desenvolvidos com as finalidades acima descritas. Estes sistemas podem ser compostos por polímeros biodegradáveis ou não-biodegradáveis ou serem formulações lipídicas. Os sistemas de transporte de drogas são representados, principalmente, pelas micro e nanopartículas e pelos implantes, sendo eles compostos por diferentes polímeros; pelos lipossomos, que são compostos por lípides e emulsionantes; e pela iontoforese, que se baseia na aplicação de corrente elétrica. Nesta revisão, as principais características dos diferentes sistemas de transporte de drogas serão descritas, expondo suas potencialidades de aplicação clínica.The diseases of the posterior segment of the eye are responsible for most cases of irreversible blindness worldwide. These conditions stimulate the development of new modalities of treatment for vitreoretinal diseases. The success in the treatment aims, mainly

  1. Uma proposta para o uso da música no segmento do turismo rural

    Directory of Open Access Journals (Sweden)

    Ivan Vilela

    2013-01-01

    Full Text Available O presente ensaio sugere propostas de uso da música no segmento do Turismo Rural, além de questionar as práticas atuais de imposição cultural efetivadas pelos mass media. Através de um breve levantamento histórico-cultural do povo brasileiro, questionamos o porquê de não utilizarmos elementos das culturas locais do Brasil no referido segmento. Sugerimos também alternativas de inclusão das potencialidades musicais locais brasileiras como forma de diferenciação dessas instituições voltadas ao turismo rural dentro do mercado.

  2. Cicloturistas na Estrada Real: Perfil, Forma de Viagem e Implicações Para o Segmento

    Directory of Open Access Journals (Sweden)

    Nelson Antônio Quadros Vieira Filho

    2011-05-01

    Full Text Available Este artigo pretende contribuir para a discussão do cicloturismo e suas especificidades como segmento turístico, a partir de um estudo de caso dos cicloturistas na Estrada Real, Minas Gerais, Brasil. O trabalho realizado objetiva caracterizar o perfil socioeconômico dos viajantes da rota turística, suas formas de viagem e suas necessidades enquanto turistas. As discussões teóricas desta pesquisa abordam os temas da segmentação turística e cicloturismo. A metodologia da pesquisa envolveu análise de entrevistas semi-estruturadas, realizadas com 28 cicloturistas, que percorreram trechos da Estrada Real, no ano de 2007, e também observação participante, a partir de viagem com um dos entrevistados, na rota turística, em Outubro de 2007. Este estudo revela as qualidades do segmento cicloturismo, que podem beneficiar tanto os turistas quanto os residentes e suas regiões. No entanto, para que o fluxo de cicloturistas seja relevante para os destinos, conclui-se ser necessário o planejamento da oferta turística em função das necessidades desse segmento.

  3. Intraocular Inflammation Associated with Ocular Toxoplasmosis : Relationships at Initial Examination

    NARCIS (Netherlands)

    Dodds, Emilio M.; Holland, Gary N.; Stanford, Miles R.; Yu, Fei; Siu, Willie O.; Shah, Kayur H.; Loon, Ninette Ten Dam-Van; Muccioli, Cristina; Hovakimyan, Anna; Barisani-Asenbauer, Talin

    2008-01-01

    PURPOSE: To describe characteristics of intraocular inflammation in eyes with active ocular toxoplasmosis and to identify relationships between signs of inflammation, complications (including elevated intraocular pressure [IOP]), other disease features, and host characteristics. DESIGN: Multicenter,

  4. Intraocular Pressure in Pregnant and Non-Pregnant Nigerian Women

    African Journals Online (AJOL)

    Erah

    A number of hormones are known to affect intraocular pressure. Of these, the female sex hormones are the predominant ones to cause variations in intraocular pressure. The aim of this study was to determine if variation in sex hormones in pregnancy affects intraocular pressure. This study was a longitudinal one.

  5. Viability of a jejunal segment after neovascularization by omentoenteropexy Viabilidade de segmento jejunal neovascularizado por omentoenteropexia

    Directory of Open Access Journals (Sweden)

    Mércia Maria Braga Rocha

    2002-01-01

    Full Text Available Omentoenteropexy was developed as an alternative technique to promote neovascularization in an isolated bowel segment. OBJECTIVE: The aim of the present protocol was to study the long-term viability of an isolated jejunal segment following neovascularization by omentoenteropexy. Long-term survival of a neovascularized bowel segment is an indication that the utilization of this segment as an intestinal graft can be successful. METHODS: To test the proposed surgical technique, 13 Wistar rats were subjected to laparotomy, the jejunum was exposed at 20 cm from the angle of Treitz and a pedicle of greater omentum was isolated. An incision of 6 cm was made along the antimesenteric jejunal border, exposing the submucosa. Omentoenteropexy was performed between the incision of the jejunum and the pedicle of the greater omentum. After seven weeks, the mesentery of the jejunal segment subjected to omentoenteropexy was ligated and isolated from the rest of the jejunum by a complete proximal and distal transversal section. Subsequently, an end-to-end anastomosis was performed to restore the continuity of the bowel. RESULTS: At 10 weeks from the first surgical intervention, the isolated jejunal segment subjected to omentoenteropexy was completely neovascularized and viable. CONCLUSION: No evidence of anatomical or functional intestinal obstruction was observed.A omentoenteropexia foi desenvolvida como uma alternativa para técnica de neovascularização em segmentos intestinais isolados, evidenciando algumas vantagens em relação a utilização de órgãos previamente descritos. OBJETIVO: Avaliar a viabilidade de um segmento jejunal neovascularizado por omentoenteropexia. MÉTODOS: Treze ratos Wistar foram submetidos a laparotomia, com exposição do jejuno vinte centímetros após o ligamento de Treitz e obtenção de um pedículo de omento. Na borda antimesentérica do jejuno foi feita uma incisão de seis centímetros com exposição da submucosa intacta

  6. DESIGN OF THE MULTIORDER INTRAOCULAR LENSES

    Directory of Open Access Journals (Sweden)

    V. G. Kolobrodov

    2015-01-01

    Full Text Available Intraocular lenses (IOLs are used to replace the natural crystalline lens of the eye. Just few basic designs of IOLs are used clinically. Multiorder diffractive lenses (MODL which operate simultaneously in several diffractive orders were proposed to decrease the chromatic aberration. Properties analysis of MODL showed a possibility to use them to develop new designs of IOLs. The purpose of this paper was to develop a new method of designing of multiorder intraocular lenses with decreased chromatic aberration. The theoretical research of the lens properties was carried out. The diffraction efficiency dependence with the change of wavelength was studied. A computer simulation of MODL in a schematic model of the human eye was carried out. It is found the capability of the multiorder diffractive lenses to focus polychromatic light into a segment on the optical axis with high diffraction efficiency. At each point of the segment is present each component of the spectral range, which will build a color image in combination. The paper describes the new design method of intraocular lenses with reduced chromaticism and with endless adaptation. An optical system of an eye with an intraocular lens that provides sharp vision of objects located at a distance of 700 mm to infinity is modeled.

  7. Associations with intraocular pressure across Europe

    DEFF Research Database (Denmark)

    Khawaja, Anthony P; Springelkamp, Henriët; Creuzot-Garcher, Catherine

    2016-01-01

    Raised intraocular pressure (IOP) is the most important risk factor for developing glaucoma, the second commonest cause of blindness globally. Understanding associations with IOP and variations in IOP between countries may teach us about mechanisms underlying glaucoma. We examined cross-sectional...

  8. Treatment Options for Intraocular (Uveal) Melanoma

    Science.gov (United States)

    ... or tans poorly. Blue or green or other light-colored eyes. Older age. Being white. Signs of intraocular melanoma include blurred vision ... to treat small tumors. This is also called light coagulation. ... are being tested in clinical trials. Information about clinical trials ...

  9. Treatment Option Overview (Intraocular [Uveal] Melanoma)

    Science.gov (United States)

    ... or tans poorly. Blue or green or other light-colored eyes. Older age. Being white. Signs of intraocular melanoma include blurred vision ... to treat small tumors. This is also called light coagulation. ... are being tested in clinical trials. Information about clinical trials ...

  10. General Information about Intraocular (Uveal) Melanoma

    Science.gov (United States)

    ... or tans poorly. Blue or green or other light-colored eyes. Older age. Being white. Signs of intraocular melanoma include blurred vision ... to treat small tumors. This is also called light coagulation. ... are being tested in clinical trials. Information about clinical trials ...

  11. Heavy and standard silicone oil: intraocular inflammation.

    Science.gov (United States)

    Russo, Andrea; Morescalchi, Francesco; Donati, Simone; Gambicorti, Elena; Azzolini, Claudio; Costagliola, Ciro; Semeraro, Francesco

    2017-03-13

    Proliferative vitreoretinopathy in the inferior retina remains clinically challenging. Heavier-than-water intraocular tamponades have been developed to improve inferior tamponading properties, and their chemical compositions have been substantially improved over the years, in parallel with developments in vitrectomy instrumentation and surgical techniques. Herein we present an updated review of the clinical use of standard formulations and HSO, focusing on analysis of the intraocular inflammation associated with endotamponade agents, and comparison of the adverse effects of these agents on the physical and biological properties of the eye. A detailed literature search was conducted on PubMed, EMBASE, Cochrane Library, and Google Scholar using the key words. Fifty-eight articles matched our inclusion criteria that were included in this systematic review. Perfluorocarbon liquids and partially fluorinated alkanes are associated with tamponade emulsification, intraocular inflammation, and rises in intraocular pressure, but these associations are not as strong when these substances are mixed with a heavy silicone oil (HSO). Two recently approved heavy silicone oil tamponades, Oxane HD and Densiron 68, are now available for use in clinical practice. While the complication spectrum of the new generation of these HSOs seems to be similar to that of conventional silicone oil tamponades, they provide better support for the inferior retina and the posterior pole. Both regular and heavy silicone oils usually yield good success rates in cases of complicated retinal detachment. Decisions as to whether to utilize heavy or regular silicone oil should be made on a case-by-case basis.

  12. Comunicación política en la red social Facebook: segmento rusoparlante 

    Directory of Open Access Journals (Sweden)

    M Pilgun

    2015-11-01

    Full Text Available Introducción. El presente artículo expone el análisis de las características de la comunicación política en el segmento rusoparlante de la red social Facebook a base de grupos políticamente activos y sus actores. Al contrario de lo habitual en los EEUU y otros países, los usuarios de blogs rusos prefieren plataformas que combinan elementos típicos de un blog y los de las redes sociales tipo Facebook. Los datos fueron recogidos en un momento político complicado para Rusia (rebeldía en Ucrania lo que avivó la actividad de la oposición rusa y los procesos manipuladores en las redes sociales rusas. Objetivos. El objetivo era clasificar los actores políticamente activos de Facebook ruso y analizar su comportamiento sociolingüístico. Metodología. Se efectuó un análisis interdisciplinar de los grupos políticos (N 200 y actores (N 291 durante enero-mayo 2014. Resultados. Según sus opiniones políticas los actores principales fueron clasificados como oficiales-gubernamentales, de oposición y nacionalistas y juzgando por su actividad como proyectores de espacio comunicativo, manipuladores, grafómanos y autores de Clusters locales. Su comportamiento comunicativo y verbal también ha sido analizado donde fueron identificadas identidades virtuales específicas compartidas. Discusión y conclusiones. Desde que las redes sociales están siendo utilizadas cada vez más con fines políticos el análisis de los procesos sociolingüísticos en las comunidades virtuales activas políticamente ha adquirido mucha importancia tanto en Rusia, como en el resto del mundo. Como la perspectiva del desarrollo futuro del presente estudio se contempla la detección de la relación entre la actividad comunicativa de los actores online y offline dentro de los grupos señalados.

  13. Characterizing intraocular tumors with photoacoustic imaging

    Science.gov (United States)

    Xu, Guan; Xue, Yafang; Gursel, Zeynep; Slimani, Naziha; Wang, Xueding; Demirci, Hakan

    2016-03-01

    Intraocular tumors are life-threatening conditions. Long-term mortality from uveal melanoma, which accounts for 80% of primary intraocular tumors, could be as high as 25% depending on the size, ciliary body involvement and extraocular extension. The treatments of intraocular tumors include eye-sparing approaches such as radiotherapy and thermotherapy, and the more aggressive enucleation. The accurate diagnosis of intraocular tumors is thereby critical in the management and follow-up of the patients. The diagnosis of intraocular tumors is usually based on clinical examination with acoustic backscattering based ultrasonography. By analyzing the high frequency fluctuations within the ultrasound (US) signals, microarchitecture information inside the tumor can be characterized. However, US cannot interrogate the histochemical components formulating the microarchitecture. One representative example is the inability of US imaging (and other contemporary imaging modalities as well) in differentiating nevoid and melanoma cells as the two types of cells possesses similar acoustic backscattering properties. Combining optical and US imaging, photoacoustic (PA) measurements encode both the microarchitecture and histochemical component information in biological tissue. This study attempts to characterize ocular tumors by analyzing the high frequency signal components in the multispectral PA images. Ex vivo human eye globes with melanoma and retinoblastoma tumors were scanned using less than 6 mJ per square centimeters laser energy with tunable range of 600-1700 nm. A PA-US parallel imaging system with US probes CL15-7 and L22-14 were used to acquire the high frequency PA signals in real time. Preliminary results show that the proposed method can identify uveal melanoma against retinoblastoma tumors.

  14. O lugar discursivo do sujeito no segmento turístico GLS

    OpenAIRE

    Tadioto, Mateus Vitor

    2016-01-01

    Esta dissertação filia-se à teoria analítica do discurso proposta pelo filósofo Michel Pêcheux e tem como tema central discussões sobre o processo de estruturação do discurso acadêmico que aborda a segmentação do Turismo no Brasil. Com essa pesquisa, busco contribuir com o estudo do Campo do Turismo a partir de uma perspectiva crítica, com foco específico no estudo do segmento caracterizado como Turismo GLS. Para tanto, busquei em livros – publicados no Brasil e escritos na comunidade acadêmi...

  15. Cicloturistas na Estrada Real: Perfil, Forma de Viagem e Implicações Para o Segmento

    OpenAIRE

    Nelson Antônio Quadros Vieira Filho; Júlio Corrêa Resende

    2011-01-01

    Este artigo pretende contribuir para a discussão do cicloturismo e suas especificidades como segmento turístico, a partir de um estudo de caso dos cicloturistas na Estrada Real, Minas Gerais, Brasil. O trabalho realizado objetiva caracterizar o perfil socioeconômico dos viajantes da rota turística, suas formas de viagem e suas necessidades enquanto turistas. As discussões teóricas desta pesquisa abordam os temas da segmentação turística e cicloturismo. A metodologia da pesquisa envolveu análi...

  16. Factors affecting intraocular pressure in lions.

    Science.gov (United States)

    Ofri, Ron; Steinmetz, Andrea; Thielebein, Jens; Horowitz, Igal H; Oechtering, Gerhard; Kass, Philip H

    2008-07-01

    The aim of this study was to conduct a detailed analysis of the relationship between age and intraocular pressure (IOP) in lions. Tonometry was conducted in 33 lions aged 5 days to 80 months. Age was significantly associated with IOP (Plions 1 year old, respectively. IOP linearly rose with age during the first 20 months of life, plateaued until approximately 40 months, and then gradually declined (r=0.85). Age-related changes in IOP were highly correlated with ultrasonographic measurements of intraocular dimensions (r > or = 0.72), and may be a determinant factor in developmental ocular growth. The dramatic rise in IOP of young lions is similar to that observed in children, but has not been previously demonstrated in animals. Significant IOP differences between lion sub-species were also demonstrated.

  17. The Visual Effects of Intraocular Colored Filters

    Directory of Open Access Journals (Sweden)

    Billy R. Hammond

    2012-01-01

    Full Text Available Modern life is associated with a myriad of visual problems, most notably refractive conditions such as myopia. Human ingenuity has addressed such problems using strategies such as spectacle lenses or surgical correction. There are other visual problems, however, that have been present throughout our evolutionary history and are not as easily solved by simply correcting refractive error. These problems include issues like glare disability and discomfort arising from intraocular scatter, photostress with the associated transient loss in vision that arises from short intense light exposures, or the ability to see objects in the distance through a veil of atmospheric haze. One likely biological solution to these more long-standing problems has been the use of colored intraocular filters. Many species, especially diurnal, incorporate chromophores from numerous sources (e.g., often plant pigments called carotenoids into ocular tissues to improve visual performance outdoors. This review summarizes information on the utility of such filters focusing on chromatic filtering by humans.

  18. [Changes in intraocular pressure depending on posture].

    Science.gov (United States)

    Barac, Ramona; Pop, Monica; Tătaru, C; Gheorghe, A; Bădescu, Silvia; Stanciu, Maria; Burcea, M

    2014-01-01

    Glaucoma is an important eye disease that, left untreated, causes irreversible blindness by affecting optic nerve threads. Decreasing intraocular pressure and maintaining it at a low level throughout the day is one of the objectives of antiglaucoma therapy. This is a prospective study conducted on a sample of 80 patients who presented at "Emergency Eye Hospital" Bucharest between 1st of December 2013 30th of July 2014. Patients were divided into two groups: 40 patients with glaucoma and 40 patients without glaucoma (control group). THE OBJECTIVE OF THE STUDY: To determine changes in intraocular pressure that may occur depending on body posture and the correlations between changes in intraocular pressure and glaucoma, obesity, hypertension. These IOP changes may be important in the progression of glaucoma regarding that one third of our time is spent on supine position during night. RESULTS AND CONCLUZIONS: IOP varies from sitting down to supine position. IOP increases in supine in most patients (with or without glaucoma) with an average of 1.25 mmHg. The increase among patients with glaucoma is higher (1.67 mmHg) compared to those without glaucoma (0.82 mmHg). In patients with hypertension and glaucoma, IOP increased with 2.62 mmHg. In patients with hypertension and obesity IOP increased with 2.5 mmHg.

  19. Processes for manufacturing multifocal diffractive-refractive intraocular lenses

    Science.gov (United States)

    Iskakov, I. A.

    2017-09-01

    Manufacturing methods and design features of modern diffractive-refractive intraocular lenses are discussed. The implantation of multifocal intraocular lenses is the most optimal method of restoring the accommodative ability of the eye after removal of the natural lens. Diffractive-refractive intraocular lenses are the most widely used implantable multifocal lenses worldwide. Existing methods for manufacturing such lenses implement various design solutions to provide the best vision function after surgery. The wide variety of available diffractive-refractive intraocular lens designs reflects the demand for this method of vision correction in clinical practice and the importance of further applied research and development of new technologies for designing improved lens models.

  20. O MERCADO DE FRANQUIAS E PEQUENAS EMPRESAS: UM ESTUDO SOBRE O SEGMENTO CAFETERIA

    Directory of Open Access Journals (Sweden)

    Ernani Cesar de Freitas

    2008-01-01

    Full Text Available O presente artigo tem como objetivo identificar fatores que influenciam o empreendedor em optar por uma franquia ou por um negócio independente no ramo de cafeteria, demonstrando as possíveis vantagens e desvantagens do sistema de franchising nesse segmento. A pesquisa descritiva realizou-se através de questionários estruturados, aplicados a franqueadores e a franqueados integrantes do sistema franchising de cafeteria no Brasil. Os resultados obtidos na pesquisa demonstram que existem diversos motivos que podem influenciar o empreendedor na escolha desse tipo de negócio; existem vantagens e desvantagens que devem ser avaliadas adequadamente para subsidiar a tomada de decisão do empreendedor. Palavras-chave: Franquias. Franchising. Empreendedor. Cafeteria.

  1. Personalización de las fórmulas de cálculo de lente intraocular Personalization of the intraocular lens calculation formulas

    Directory of Open Access Journals (Sweden)

    Juan R. Hernández Silva

    2004-12-01

    Full Text Available Este trabajo tiene la finalidad de evaluar los resultados refractivos que se alcanzan con la introducción de las constantes personalizadas en las fórmulas de tercera generación para el cálculo del lente intraocular. Se realizó un estudio descriptivo prospectivo cuyo universo está constituido por los pacientes con catarata senil y se seleccionó una muestra aleatoria de 597 casos. Los pacientes fueron clasificados en 7 grupos según las mediciones preoperatorios del promedio queratométrico y la longitud axial. Para dar salida al objetivo propuesto fueron utilizadas las siguientes variables: longitud axial, promedio queratométrico, componente esférico esperado (sep, componente esférico obtenido (ceo, dioptría de lente intraocular implantado (This paper is aimed at evaluating the refractive results attained with the introduction of personalized constants in the third generation formulas for the intraocular lens calculation. A descriptive and prospective study was conducted among the patients with senile cataract, and a randomized sample of 597 cases was selected. Patients were classified into 7 groups according to the preoperative measurements of the keratometric average and the axial longitude. To obtain the proposed objective, the following variables were used: axial longitude, keratometric average, expected spherical component (sep, obtained spherical component (ceo, dioptry of implanted ocular lens (<16, of 17-19, 20-23, 24-27, 28-30 and refractive results. The statistical analysis of the results was made by a varianze analysis, the T test of comparison of means for matched data and Ji square. A confidence level of 95.5 was used. The utilization of personalized constants in the calculation of intraocular lens increased by more than 20 % the good refractive results. No differences were observed in the diverse groups of patients, the type of formula used and the dioptric power of the lens.The S3652 and S3602 lens models presented a

  2. Tear Film Functions and Intraocular Pressure Changes in Pregnancy.

    African Journals Online (AJOL)

    AJRH Managing Editor

    employed to assess visual acuity, tear break up time (TBUT), Schirmer's test (ST), intraocular pressure (IOP) on all subjects. The mean values for IOP ... Keywords: Tear break-up time, Schirmer's test, intraocular pressure, pregnancy. Résumé ..... Goldich Y, Cooper M, Barkana Y, Tovbin J, Lee Ovadia. K, Avni I, Zadok D.

  3. Tear production and intraocular pressure in canine eyes with ...

    African Journals Online (AJOL)

    Tear production and intraocular pressure in canine eyes with corneal ulceration. David L. Williams, Philippa Burg. Abstract. This study aimed to evaluate changes in lacrimation and intraocular pressure (IOP) in dogs with unilateral corneal ulceration using the Schirmer tear test (STT) and rebound (TonoVet®) tonometry.

  4. Acute Retention of Urine Following Intraocular Surgery | Nwosu ...

    African Journals Online (AJOL)

    Hyperosmolar agents and carbonic anhydrase inhibitors are used to lower the intraocular pressure and thus minimize the chances of vitreous loss during intraocular surgery. However, these agents could precipitate urinary retention. This is a report on two elderly men who had perioperative acute urinary retention following ...

  5. Primary intraocular chondrosarcoma in a dog

    Directory of Open Access Journals (Sweden)

    E. Perlmann

    2013-12-01

    Full Text Available A five-year-old male Cocker Spaniel was presented for evaluation of the right eye due to discomfort, abundant purulent discharge and progressive enlargement of the eyeball. The owner revealed that the right eye has appeared to be inflamed and smaller then the left eye for years. Ophthalmic examination revealed corneal perforation, buphthalmia and conjuctival hyperemia. Enucleating was performed due to signs of endophthalmitis and ocular discomfort. Histopathology revealed a multilobulated proliferation of chondrocytes producing hyaline cartilage with occasional pleomorphism and binucleate cells. A diagnosis of primary intraocular chondrosarcoma was done.

  6. Implantable intraocular pressure monitoring systems: Design considerations

    KAUST Repository

    Arsalan, Muhammad

    2013-12-01

    Design considerations and limitations of implantable Intraocular Pressure Monitoring (IOPM) systems are presented in this paper. Detailed comparison with the state of the art is performed to highlight the benefits and challenges of the proposed design. The system-on-chip, presented here, is battery free and harvests energy from incoming RF signals. This low-cost design, in standard CMOS process, does not require any external components or bond wires to function. This paper provides useful insights to the designers of implantable wireless sensors in terms of design choices and associated tradeoffs. © 2013 IEEE.

  7. On the retinal toxicity of intraocular glucocorticoids.

    Science.gov (United States)

    Torriglia, Alicia; Valamanesh, Fatemeh; Behar-Cohen, Francine

    2010-12-15

    Corticosteroids are hormones involved in many physiological responses such as stress, immune modulation, protein catabolism and water homeostasis. The subfamily of glucocorticoids is used systemically in the treatment of inflammatory diseases or allergic reactions. In the eye, glucocorticoides are used to treat macular edema, inflammation and neovascularization. The most commonly used glucocorticoid is triamcinolone acetonide (TA). The pharmaceutical formulation of TA is not adapted for intravitreal administration but has been selected by ophthalmologists because its very low intraocular solubility provides sustained effect. Visual benefits of intraocular TA do not clearly correlate with morpho-anatomical improvements, suggesting potential toxicity. We therefore studied, non-common, but deleterious effects of glucocorticoids on the retina. We found that the intravitreal administration of TA is beneficial in the treatment of neovascularization because it triggers cell death of endothelial cells of neovessels by a caspase-independent mechanism. However, this treatment is toxic for the retina because it induces a non-apoptotic, caspase-independent cell death related to paraptosis, mostly in the retinal pigmented epithelium cells and the Müller cells. Copyright © 2010 Elsevier Inc. All rights reserved.

  8. Intraocular pressure instability after 23-gauge vitrectomy.

    Science.gov (United States)

    Singh, Christopher N; Iezzi, Raymond; Mahmoud, Tamer H

    2010-04-01

    The purpose of this study was to describe outcomes, trends, risk factors, and protective factors for intraocular pressure (IOP) spikes in patients undergoing 23-gauge pars plana vitrectomy. A retrospective review in an academic institution was performed on all eyes undergoing 23-gauge vitrectomy with at least 1-month follow-up. The main outcome measures included IOP and operative complications. Ninety-seven eyes of 93 patients were included. Intraocular pressure spikes >22 in the first month occurred in 73% of eyes with or suspect for glaucoma versus 46% of eyes without (P = 0.017); 76% of eyes with a gas fill versus 44% of eyes with a fluid fill (P = 0.0036); and 21% of eyes started on IOP-lowering drops on postoperative day 1 versus 49% of eyes who were not (P = 0.0033). Complications included retinal tears (3%), intraoperative retinal detachment (2%), and postoperative retinal detachment (2%). Fifteen percent of eyes required suturing of at least one sclerotomy. There were no cases of postoperative hypotony or endophthalmitis. Patients with or suspect for glaucoma or those with a gas fill may be at risk for high postoperative IOP during the first month. Aggressive early treatment of IOP may prevent IOP spikes in the early postoperative period.

  9. Sutureless Intrascleral Fixated Intraocular Lens Implantation.

    Science.gov (United States)

    Karadag, Remzi; Celik, Haci Ugur; Bayramlar, Huseyin; Rapuano, Christopher J

    2016-08-01

    To review sutureless intrascleral intraocular lens (IOL) fixation methods. Review of published literature. Sutureless intrascleral IOL fixation methods are newer and have been developed to eliminate the suture-related complications of sutured scleral fixation methods such as suture-induced inflammation or infection and IOL dislocation or subluxation due to suture degradation or suture breakage. Sutureless intrascleral fixation methods aim for intrascleral haptic fixation to achieve stability of the IOL. Various methods of sutureless scleral fixation have been described. Using a needle, a blade, or a trochar, sclerostomies are created in all techniques for intraocular access. Some surgeons prefer to create scleral tunnels, whereas others use scleral flaps for scleral fixation of haptics. The stability of IOLs is attained by the scar tissue formed around the haptics. Short-term results of these new methods are acceptable; studies including more cases with longer follow-up are needed to determine their long-term success. [J Cataract Refract Surg. 2016;32(9):586-597.]. Copyright 2016, SLACK Incorporated.

  10. Los precios forward sobre electricidad. ¿Determinados racionalmente por los agentes del mercado colombiano?

    OpenAIRE

    Salazar Marín, Gloria Stella; Pantoja, Javier

    2012-01-01

    El artículo considera las transacciones a plazo sobre electricidad que los agentes del mercado eléctrico en Colombia, en sus diferentes segmentos, hacen por medio de contratos forward, con el fin de asegurar el precio de compra/venta. El comportamiento aleatorio de los precios y las cantidades que se manejan de flujo eléctrico implican el sacrificio de alguno de los agentes, dependiendo del segmento —regulado, no-regulado o intermediación— en el que se realice la operación. Además, la prima q...

  11. KINEMATICS ANALYSIS OF A PARALLEL ROBOT WITH A PASSIVE SEGMENT ANÁLISIS DE LA CINEMÁTICA DE UN ROBOT PARALELO CON UN SEGMENTO PASIVO

    Directory of Open Access Journals (Sweden)

    Abdelhakim Cherfia

    2007-08-01

    Full Text Available This paper presents a geometrical model of a constrained robot of three degrees of freedom (d.o.f added to a PPP passive central segment. This structure provides a pure translation motion. We will also determine the relations between generalized and articular velocities by using the inverse Jacobian matrix. Further, we determine the reciprocal relations between cartesian and angular velocities of the end-effector via articular velocities by simple derivation of the direct geometrical model expressions. A determination of the workspace based on the geometrical model analysis is derived followed by a numerical calculation of all the atteignables points enabling a graphical visualisation of such a workspace. Moreover, the analysis of the Jacobian matrix has permitted to ensure that there are no singularities of type 1 and 2 in such a structure. A prototype of a parallel robot has been built up in our laboratory in order to validate the proposed models.Este trabajo presenta el modelo geométrico de un robot paralelo con tres grados de libertad (d.o.f agregados a un segmento central pasivo del PPP. Esta estructura proporciona un movimiento de translación pura. También determinaremos las relaciones entre las velocidades generalizadas y articulares usando la matriz Jacobiana inversa. Además, determinamos las relaciones recíprocas entre las velocidades cartesianas y angulares del end-effector vía velocidades articulares por la derivación simple de las expresiones del modelo geométrico directo. Una determinación del espacio de trabajo basado en el análisis del modelo geométrico es derivado seguido por un cálculo numérico de todos los puntos que deben alcanzarse permitiendo una visualización gráfica de tal espacio de trabajo. Por otra parte, el análisis de los coeficientes de la matriz Jacobiana permite asegurar que no haya singularidades del tipo 1 y 2 en tal estructura. Se ha realizado un prototipo de robot paralelo en nuestro laboratorio

  12. Beta2 adrenergic receptor silencing change intraocular pressure in New Zealand rabbits

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    Patricia Loma

    2018-04-01

    Full Text Available Purpose/aim: Glaucoma consists of a group of progressive optic neuropathies that are characterized by degeneration of the optic nerve and irreversible visual filed loss. Elevated intraocular pressure is the only proven treatable risk factor and commercial products used for glaucoma treatment are focused in lowering intraocular pressure. These drugs can have various undesirable side effects and this invites to look for new strategies. The purpose of this work is to study the use of a siRNA (small interfering RNA to selectively silence beta2 adrenergic receptors and to see whether it reduces IOP (intraocular pressure. Material and methods: Topical instillation of beta2 adrenergic receptors small-interfering RNA (siRNA, 25–250 μg was applied and IOP was measured with a Tonopen XL up to 9 consecutive days. The effect of such siRNA was compared to commercial compounds such as Timoftlol, Trusopt and Xalatan, and it was also analyzed if some anatomical changes occurred by microscopy. Results: siRNA designed for beta2 adrenergic receptor induced a reduction of intraocular pressure (IOP of 30 ± 5%, compared to a control (scrambled siRNA. The results in terms of IOP decrease were similar to that found with commercial compounds but a long-lasting hypotensive action was shown by beta2 adrenergic receptor siRNA treatment as compared to commercial drugs. No apparent side effects were observed in the ocular structures. Conclusion: The use of siRNA against the beta2 adrenergic receptors could provide an interesting therapeutic strategy for glaucoma treatment. Resumen: Objetivo: El glaucoma consiste en un grupo de neuropatías ópticas progresivas caracterizadas por degeneración del nervio óptico y pérdida irreversible del campo visual. La elevación de la presión intraocular es el único factor de riesgo tratable probado, centrándose los productos comerciales para el tratamiento del glaucoma en la reducción de la presión intraocular. Estos f

  13. A study of Brachytherapy for Intraocular Tumor

    International Nuclear Information System (INIS)

    Ji, Kwang Soo; Yoo, Dae Hyun; Lee, Sung Goo; Kim, Jae Hu; Ji, Young Hun

    1996-01-01

    The eye enucleation or external-beam radiation therapy that has been commonly used for the treatment of intraocular tumor have demerits of visual loss and in deficiency of effective tumor dose. Recently, brachytherapy using the plaques containing radioisotope-now treatment method that decrease the demerits of the above mentioned treatment methods and increase the treatment effect-is introduced and performed in the countries, Our purpose of this research is to design suitable shape of plaque for the ophthalmic brachytherapy, and to measure absorbed doses of Ir-192 ophthalmic plaque and thereby calculate the exact radiation dose of tumor and it's adjacent normal tissue. In order to brachytherapy for intraocular tumor, 1. to determine the eye model and selected suitable radioisotope 2. to design the suitable shape of plaque 3. to measure transmission factor and dose distribution for custom made plaques 4. to compare with the these data and results of computer dose calculation models. The result were as followed. 1. Eye model was determined as a 25 mm diameter sphere, Ir-192 was considered the most appropriate as radioisotope for brachytherapy, because of the size, half, energy and availability. 2. Considering the biological response with human tissue and protection of exposed dose, we made the plaques with gold, of which size were 15 mm, 17 mm and 20 mm in diameter, and 1.5 mm in thickness. 3. Transmission factor of plaques are all 0.71 with TLD and film dosimetry at the surface of plaques and 0.45, 0.49 at 1.5 mm distance of surface, respectively. 4. As compared the measured data for the plaque with Ir-192 seeds to results of computer dose calculation model by Gary Luxton et al. and CAP-PLAN (Radiation Treatment Planning System), absorbed doses are within ±10% and distance deviations are within 0.4 mm Maximum error is -11.3% and 0.8 mm, respectively. As a result of it, we can treat the intraocular tumor more effectively by using custom made gold plaque and Ir-192

  14. MicroRNA profiling in intraocular medulloepitheliomas.

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    Deepak P Edward

    Full Text Available To study the differential expression of microRNA (miRNA profiles between intraocular medulloepithelioma (ME and normal control tissue (CT.Total RNA was extracted from formalin fixed paraffin embedded (FFPE intraocular ME (n=7 and from age matched ciliary body controls (n=8. The clinical history and phenotype was recorded. MiRNA profiles were determined using the Affymetrix GeneChip miRNA Arrays analyzed using expression console 1.3 software. Validation of significantly dysregulated miRNA was confirmed by quantitative real-time PCR. The web-based DNA Intelligent Analysis (DIANA-miRPath v2.0 was used to perform enrichment analysis of differentially expressed (DE miRNA gene targets in Kyoto Encyclopedia of Genes and Genomes (KEGG pathway.The pathologic evaluation revealed one benign (benign non-teratoid, n=1 and six malignant tumors (malignant teratoid, n=2; malignant non-teratoid, n = 4. A total of 88 miRNAs were upregulated and 43 miRNAs were downregulated significantly (P<0.05 in the tumor specimens. Many of these significantly dysregulated miRNAs were known to play various roles in carcinogenesis and tumor behavior. RT-PCR validated three significantly upregulated miRNAs and three significantly downregulated miRNAs namely miR-217, miR-216a, miR-216b, miR-146a, miR-509-3p and miR-211. Many DE miRNAs that were significant in ME tumors showed dysregulation in retinoblastoma, glioblastoma, and precursor, normal and reactive human cartilage. Enriched pathway analysis suggested a significant association of upregulated miRNAs with 15 pathways involved in prion disease and several types of cancer. The pathways involving significantly downregulated miRNAs included the toll-like receptor (TLR (p<4.36E-16 and Nuclear Factor kappa B (NF-κB signaling pathways (p<9.00E-06.We report significantly dysregulated miRNAs in intraocular ME tumors, which exhibited abnormal profiles in other cancers as well such as retinoblastoma and glioblastoma. Pathway analysis

  15. Lente intra-ocular multifocal difrativa apodizada: resultados Diffractive apodized multifocal intraocular lens: results

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    Virgilio Centurion

    2007-12-01

    Full Text Available OBJETIVO: Mostrar os resultados visuais e refracionais com lente intra-ocular multifocal difrativa apodizada. MÉTODOS: Estudo de 100 olhos de 50 pacientes com catarata, submetidos à facoemulsificação com implante bilateral de lente intra-ocular (LIO multifocal difrativa apodizada. Foi avaliada a acuidade visual binocular sem e com correção para longe e perto, a previsibilidade refracional e a freqüência de uso de óculos. RESULTADOS: A acuidade visual sem correção para longe foi de e " 20/30 em 97,56% dos olhos operados e e" J2 em 100%, sendo que 82% dos pacientes nunca usam óculos e 16% usam de forma esporádica. CONCLUSÃO: A LIO multifocal difrativa apodizada mostrou ser uma opção previsível, reproduzível e segura na correção dos vícios de refração para longe e perto durante a cirurgia da catarata, permitindo elevado índice de independência ao uso de óculos.OBJECTIVE: To show visual and refraction results using multifocal diffractive apodized intraocular lens. METHODS: The study of 100 eyes of 50 patients with cataract, submitted to phacoemulsification with bilateral implant of multifocal diffractive apodized intraocular lens (IOL. Binocular visual acuity was evaluated with and without correction for near and distance, and refraction previsibility and frequency of wearing glasses. RESULTS: Visual acuity without correction for distance was e" 20/30 in 97.56% of eyes operated on and e" J2 in 100%, of these 82% of patients never wear glasses and 16% wear glasses sporadically. CONCLUSION: Multifocal diffractive apodized IOL proved to be a foreseeable option, reproducible and safe in the correction of refraction errors for distance and near during cataract surgery, enabling a high rate of independence from the use of glasses.

  16. Análise de rentabilidade dos segmentos de mercado de empresa distribuidora de mercadorias

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    Rodney Wernke

    2004-08-01

    Full Text Available O artigo apresenta possíveis aplicações do conceito de margem de contribuição para avaliação de desempenho de segmentos comerciais, voltando-se mais especificamente para empresas que operam no ramo de distribuição de mercadorias. São comentadas e exemplificadas situações em que a margem de contribuição pode servir como ferramenta de apoio aos gestores da área de vendas para averiguar a rentabilidade de produtos, linhas de mercadorias, territórios de venda, canais de distribuição, clientes e vendedores. Por último enfatiza-se o aspecto da projeção de resultados operacionais com base na contribuição total e seus benefícios.The article presents possible applications of the contribution margin concept for the performance evaluation of commercial segments, more specifically oriented towards goods distribution companies. We comment on and give examples of situations in which the contribution margin can serve as a tool to support managers from the sales area to verify the profitability of products, product lines, sales regions, distribution channels, clients and salespersons. Finally, we emphasize the aspect of operational result projection on the basis of the total contribution and its benefits.

  17. DESEMPENHO IMPORTADOR DO SEGMENTO DE MODA PRAIA BRASILEIRO: UMA PROPOSTA DE ANÁLISE

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    Ana Elizabeth Moiseichyk

    2012-07-01

    Full Text Available O vasto litoral brasileiro aliado a uma cultura de seu uso como meio de lazer propiciou ao país o surgimento de inúmeras empresas especializadas na produção e comercialização da moda praia. No entanto, existe um grupo de clientes que buscam produtos importados, mesmo neste segmento. Neste sentido, este estudo teve como objetivo caracterizar a importação brasileira de moda praia feminina, investigando qual é sua importância e participação no contexto internacional, pelos desafios propostos pela competição entre os diversos players e a necessidade de conhecimentos sobre inovação para se manter no mercado importador. Apoiado na análise de conteúdo da documentação temática com dados quantitativos e oficiais coletados no portal Aliceweb do Ministério do Desenvolvimento, Indústria e Comércio Exterior do Brasil obteve-se como resultado final do estudo a estruturação de uma tabela com os 10 principais países fornecedores e o comportamento de compra, onde, em 2011, o principal expoente foi a China com 90,9% da quantidade importada com 959.324 peças compradas, valor médio US$ 2,17 FOB, desempenho de compra em crescimento e tendência de preço em queda.

  18. PENETRATING OCULAR INJURY WITH RETAINED INTRAOCULAR FOREIGN BODY FROM DRYWALL.

    Science.gov (United States)

    Syed, Reema; Kim, Sung-Hye; Palacio, Agustina; Nunery, William R; Schaal, Shlomit

    2018-03-23

    To present a case of open globe injury and retained intraocular foreign body secondary to drywall. Interventional case report. A 21-year-old man presented with corneal laceration, iris defect, and vitreous hemorrhage after hammering drywall. Computed tomography scan was negative for intraocular foreign body, but a drywall intraretinal foreign body was found on 25-gauge vitrectomy. Intraoperative findings and 6-month follow-up are presented. Intraocular foreign body must always be suspected in all cases of penetrating ocular trauma. Although magnetic resonance imaging is ideal in diagnosing nonmetallic foreign bodies, computed tomography scan with Hounsfield units should be used in an emergency setting.

  19. Correlação entre a citologia e a histologia nas lesões intra-oculares suspeitas de malignidade Cytologic-histologic correlation in intraocular lesions with suspicion of malignancy

    Directory of Open Access Journals (Sweden)

    Zélia Maria da Silva Corrêa

    2003-06-01

    Full Text Available OBJETIVO: Correlacionar os achados citológicos da biópsia aspirativa com agulha fina (BAAF de lesões intra-oculares suspeitas de malignidade com a histopatologia obtida quando o tratamento de escolha foi enucleação ou ressecção da lesão tumoral. MÉTODOS: Análise retrospectiva de 51 pacientes submetidos à biópsia aspirativa com agulha fina com fins diagnósticos ou para correlação cito-histológica. Foram excluídos os casos com lesões não sólidas, tratamento conservador e biópsias guiadas por ultra-som. Após exclusões, 20 olhos de pacientes contendo lesões intra-oculares suspeitas de malignidade foram estudados, sendo 12 do sexo feminino, com idades entre 2 e 78 anos. Todas biópsias foram realizadas pela primeira autora sob observação direta (microscópio ou indireta (oftalmoscopia binocular indireta. A rota escolhida foi transaquosa para os tumores de segmento anterior e transvítrea com acesso escleral para os tumores de segmento posterior, exceto os casos suspeitos de retinoblastoma, biopsiados com acesso pela periferia da córnea. Foram obtidas 2 amostras de áreas diferentes do tumor em todos os casos com agulha calibre 25. As amostras colhidas foram encaminhadas para processamento, fixação e coloração pelo método de Papanicolaou e hematoxilina-eosina. Os espécimens obtidos para histopatologia foram corados pela hematoxilina-eosina. RESULTADOS: Três casos eram tumores de segmento anterior (íris e 17 de segmento posterior, sendo 3 retinoblastomas. Nove pacientes foram submetidos à biópsia aspirativa com agulha fina com fins diagnósticos e 11 para correlação cito-histológica após enucleação. Somente dois casos apresentaram quantidade insuficiente de material para diagnóstico e posteriormente revelaram ser um granuloma e um melanoma maligno de coróide. CONCLUSÕES: A biópsia aspirativa com agulha fina parece ser um método diagnóstico confiável baseado na correlação cito-histológica neste grupo

  20. Intraocular Surgery in Kyphosis: An Easier Approach

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    Karanjit S. Kooner

    2013-06-01

    Full Text Available We describe a 49-year-old man with advanced kyphosis and dense cataract, who could only recline to about 40° from the vertical axis despite a maximal reverse Trendelenburg position and pillows under the head, neck, shoulders and knees. With a single corneal retraction suture at 6 o'clock, the eye could be rotated horizontally, which enabled the surgeon to perform a complex cataract surgery despite prior glaucoma shunt, posterior synechiae, a small pupil and the need to stain the capsule. As the eye can be brought into any desired position with a retraction suture, patients with kyphosis or other conditions that prevent them from assuming a supine position can still have safe intraocular procedures. This maneuver reduces the need to tilt patients to an uncomfortable position that may cause pain, increased breathing difficulty and elevated posterior vitreous pressure.

  1. Intraocular lens implantation in microphthalmic patients.

    Science.gov (United States)

    Sinskey, R M; Amin, P; Stoppel, J

    1992-09-01

    Microphthalmos is a developmental disorder of the eye consisting of a smaller than normal eye. This disorder can present as an isolated condition or associated with other systemic alterations. It is not uncommon for patients with microphthalmos to have congenital cataracts along with other ocular and systemic abnormalities. This paper reports the experience with 11 microphthalmic eyes of seven patients who had primary or secondary intraocular lens (IOL) implantation over a six-year period from 1985 to 1991. In all cases the IOL had a 13.5 mm or 14.0 mm overall diameter and a 6.0 mm or 6.5 mm optic. It was difficult to obtain documentation of objective visual improvement in many of these cases because of the associated nystagmus. However, all patients reported subjective improvements. These results suggest that with proper technique and lens selection microphthalmic patients should be considered for IOL implantation with relative safety and success.

  2. Duration of intraocular gases following vitreoretinal surgery.

    Science.gov (United States)

    Kontos, Andreas; Tee, James; Stuart, Alastair; Shalchi, Zaid; Williamson, Tom H

    2017-02-01

    Intraocular gas tamponades are an important tool in modern vitreoretinal surgery. However, there is considerable variation in their use and perceptions amongst clinicians regarding these agents. An electronic survey of vitreoretinal surgeons in the UK was undertaken to establish the patterns of use and surgeons' estimates of the longevity and expansion timing of gas tamponades. In addition, data were prospectively collected on the longevity of gas tamponades in 114 patients from our unit. An analysis was performed to identify patient or surgery factors affecting gas longevity RESULTS: A wide variation in the patterns of use and estimates of longevity and expansion timing of intraocular tamponades was found in the survey of vitreoretinal surgeons. Data from our unit give informed estimates on the longevity of three commonly used tamponades. For 30 % sulphur hexafluoride (SF6), mean 18.0 days, standard deviation (SD) 2.6 days. For 20 % hexafluoroethane (C2F6), mean 34.5 days, SD 3.3 days. For 15 % perfluoropropane (C3F8), mean 67.7 days SD 5.5 days. In the C2F6 group there was correlation between longer duration of the gas bubble and longer axial length (r = 0.438, p = 0.02) and longer gas duration with male sex (p = 0.002). We present informed gas tamponade longevity figures in clinical practice and report statistically significant associations between longer gas longevity and increasing axial length and male sex.

  3. Patient acceptability of the Tecnis® multifocal intraocular lens

    Directory of Open Access Journals (Sweden)

    Sood P

    2011-03-01

    Full Text Available Priyanka Sood1, Maria A Woodward21Emory Eye Center, Atlanta, GA, USA; 2Kellogg Eye Center, Ann Arbor, MI, USAAbstract: Cataract surgery has evolved. The goal of the surgeon includes both restoration of vision and refinement of vision. Patients' desire for spectacle independence has driven the market for presbyopia-correcting cataract surgery and development of novel intraocular lens (IOL designs. The Tecnis® Multifocal Intraocular Lens incorporates an aspheric, modified anterior prolate IOL with a diffractive multifocal lens design. The design aims to minimize spherical aberration and improve range of focus. The purpose of this review is to assess patient acceptability of the Tecnis® multifocal intraocular lens.Keywords: Tecnis®, intraocular lens, multifocal, presbyopia 

  4. IOL Implants: Lens Replacement and Cataract Surgery (Intraocular Lenses)

    Science.gov (United States)

    ... Cataract Surgery vs. Laser-Assisted Cataract Surgery Cataract Vision Simulator Cataract Pictures and Videos: What Do ... Mar. 27, 2018 An intraocular lens (or IOL) is a tiny, artificial lens for the eye. It replaces the eye's ...

  5. [Treatment for penetrating wound caused by metallic intraocular foreign body].

    Science.gov (United States)

    Pienaru, M; Şerban, Ramona; Baltă, F

    2014-01-01

    Penetrating wounds with intraocular foreign body are ophthalmologic emergencies due to their severity and complexity and may require multiple surgeries for final resolution. 30-years-old patient with penetrating wound and metallic intraocular foreign body in the posterior vitreous requires successive operations for IOFB extraction, lensectomy, posterior vitrectomy for rhegmatogenous retinal detachment and then silicone oil extraction with final visual acuity 0, 4 PH.

  6. Relation between intraocular pressure and size of transverse sinuses

    Energy Technology Data Exchange (ETDEWEB)

    Kantarci, Mecit; Onbas, Omer; Alper, Fatih; Okur, Adnan [Atatuerk University, Department of Radiology, Medical Faculty, Erzurum (Turkey); Dane, Senol; Gumustekin, Kenan [Atatuerk University, Department of Physiology, Medical Faculty, Erzurum (Turkey); Aslankurt, Murat [Atatuerk University, Department of Ophtalmatology, Medical Faculty, Erzurum (Turkey); Yazici, Ahmet Taylan [Beyoglu Goez Egitim ve Arastirma Hastanesi, Istanbul (Turkey)

    2005-01-01

    There are asymmetries in the sizes of transverse sinus and intraocular pressure. The purpose of this study was to investigate possible relationships between the asymmetry of transverse sinuses in TOF MR venography and intraocular pressures of right and left eyes. In this study, subjects were 63 male and 42 female medical school students, aged 18-21 years (mean{+-}SD; 19.72{+-}0.67 years). Subjects with neurological and ophthalmologic disease, particularly dural sinus thrombosis, myopia, trauma and glaucoma, were excluded the study. Subjects were divided into five groups according to the magnitudes of the right- and left-transverse sinuses in MR venography results. There is a functional relation between intraocular pressures of the right and left eyes and asymmetry of the transverse sinus. If the transverse sinus on one side is larger and its venous drainage is greater, the intraocular pressure of the eye on this side is lower. It can be speculated that the transverse sinus size may be associated with pathogenesis of diseases with increased intraocular pressure such as glaucoma. We aim to determine the relation between the size and drainage of transverse sinuses in TOF MR venography and intraocular pressure in patients with open-angle glaucoma in our next study. (orig.)

  7. La institucionalidad del salario mínimo en Brasil

    OpenAIRE

    Neri, Marcelo Cortes; Moura, Rodrigo Leandro de

    2005-01-01

    El reajuste del salario mínimo (SM) es una de las materias de política pública que suscita más debate en Brasil, debido a sus múltiples efectos sobre los más diversos segmentos de la economía. Por ejemplo, si aumentara demasiado, se podría generar un deterioro en la cantidad y calidad del empleo, dado que se perderían algunos puestos de trabajo, mientras que en otros habría una migración hacia el sector informal del merca do de trabajo. Paralelamente, el incremento del SM produce una ganancia...

  8. Perdurabilidad y competitividad en bancos comerciales segmento masivo, tamaño intermedio: caso Colpatria

    OpenAIRE

    Zárate Cotrino, Laura Natalia

    2015-01-01

    Teniendo en cuenta la complejidad del sistema financiero colombiano y su alto impacto en la economía nacional, surge el interés de realizar un estudio y análisis cualitativo y cuantitativo de diversos agentes de este sector. A partir de allí, se genera un diagnóstico de morbilidad, hacinamiento e imitación en el sector, así como de perdurabilidad del Banco Colpatria Durante el documento se hará énfasis en la estrategia de redes y alianzas del sector estudiado, el cual, según revisión, prom...

  9. Papel de los biomarcadores en el síndrome coronario agudo sin elevación del segmento ST

    OpenAIRE

    Puche Morenilla, Carmen María

    2010-01-01

    Acute coronary syndromes are a group of clinical entities with a common denominator: the partial or total obstruction of a coronary artery by a thrombosis caused by rupture or erosion of a vulnerable plaque. The relative value of classic markers, myocardial damage variables, and levels of acute-phase reactants in establishing the pre-discharge prognosis of acute coronary syndrome without ST-segment elevation was analyzed. We propuse to evaluate these markers in serum of patients admitte...

  10. Actuación urgente ante el infarto agudo de miocardio con elevación del segmento ST (IAMCEST)

    OpenAIRE

    Fernández Suárez, María

    2016-01-01

    Introducción: El infarto agudo de miocardio (IAM) es una de las primeras causas de muerte tanto en España como en todo el mundo. Según la OMS, se identifica por la presencia de al menos dos de los siguientes criterios: dolor torácico típico o atípico sugestivo de isquemia, elevación de marcadores de macronecrosis ó cambios electrocardiográficos (ECG) característicos con presencia de ondas Q patológicas. El tratamiento de elección es la reperfusión, ya sea mediante fibrinolisis o angioplastia ...

  11. Changes of intraocular pressure during experimental vitrectomy.

    Science.gov (United States)

    Kim, Seung Hoon; Choi, Kyung Seek

    2012-08-01

    To compare the infusion pressure shown by a vitrectomy device with the actual intraocular pressure (IOP) observed during pars plana vitrectomy. Furthermore, we evaluated the effects of variable parameters on the actual IOP during vitrectomy surgery. Porcine eyes were obtained within 24 h of slaughter. Actual IOP was measured by a digital manometer during vitrectomy using the vented gas forced infusion (VGFI) system, as well as the gravity system. We analyzed the actual IOP according to the groups divided by remnant volume of infusion fluid: (500 ml; control group, 250, 125, and 50 ml). Finally, actual IOP was determined after changing variable parameters such as cutting rate, vacuum pressure, and the VGFI setting. Settings for a VGFI system and pressure supplied by a gravity system significantly correlated with actual IOP (r = 0.99, p = 0.0001; r = 0.99, and p = 0.0001). Actual IOP declined with decreasing volume of infusion fluid. If the volume of infusion fluid was pressure affected actual IOP. Infusion pressure shown by the vitrectomy device was similar to actual IOP in porcine eyes. However, volume of infusion fluid and variable parameters could change the actual IOP during pars plana vitrectomy. Our results may help to optimize the ideal parameters such as infusion pressure, vacuum pressure, and cutting rate of vitrectomy systems used to treat vitreoretinal diseases.

  12. O Desenvolvimento do Enoturismo no Vale do São Francisco: um segmento em expansão

    Directory of Open Access Journals (Sweden)

    Pollyana Pugas Dias

    2012-12-01

    Full Text Available Resumo

    A região do Vale do São Francisco vem se destacando no cenário nacional como o mais novo destino enoturístico. A atividade cresce no mundo como uma alternativa interessante para as regiões vitivinicultoras agregarem valor aos seus produtos e diversificarem a fonte geradora de renda ao mesmo tempo em que envolvem outros setores da região, distribuindo os frutos do seu negócio. Por meio da realização de entrevistas e de uma extensa pesquisa de dados secundários, este trabalho objetivou descrever como esse processo vem se desenvolvendo em pleno semiárido nordestino. Verificou-se como principais evidências do franco crescimento do enoturismo no Vale do São Francisco o envolvimento crescente das vinícolas da região com a atividade, o forte investimento do poder público em prol do segmento e a recente diversificação dos produtos turísticos oferecidos. Os bons resultados que o enoturismo vem apresentando na região podem ser atribuídos ao esforço e integração dos agentes envolvidos e ao contraste de paisagens promovido pela inserção da atividade de fruticultura irrigada, e deve ser interpretada como ferramenta de transformação social e econômica.

    Palavras-chave: turismo; Vale do São Francisco; vitivinicultura. AbstractThe region

  13. Intraocular stability of an angle-supported phakic intraocular lens with changes in pupil diameter.

    Science.gov (United States)

    Alió, Jorge L; Piñero, David P; Sala, Esperanza; Amparo, Francisco

    2010-09-01

    To use anterior segment optical coherence tomography (AS-OCT) to evaluate the stability of a recently released angle-supported phakic intraocular lens (pIOL) in the anterior segment with changes in pupil diameter. Keratoconus Unit, Vissum Corporation, Alicante, Spain. In this observational cross-sectional study of consecutive eyes with moderate to high myopia, an AcrySof Cachet pIOL was implanted with the aim of minimizing the refractive error. An analysis of the position and stability of the pIOL before and after pharmacologic pupil dilation was performed 3 months postoperatively using the Visante AS-OCT system. A measurement protocol that included several anatomic parameters was developed and applied; the parameter values before and after dilation were compared. Twenty eyes of 20 patients ranging in age from 24 to 48 years old were evaluated. The anterior chamber depth increased significantly with pupil dilation (mean change 0.06 mm +/- 0.08 [SD]) (Por=.14). The angle-supported pIOL showed excellent intraocular behavior after pupil dilation, with no shortening of the distance between the pIOL and corneal endothelium at the center or peripheral edges of the pIOL. Copyright (c) 2010 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  14. Divulgação de Informações por Segmento: Panorama da Aplicação do CPC 22

    Directory of Open Access Journals (Sweden)

    Valdirene Gasparetto

    2013-06-01

    Full Text Available O objetivo da pesquisa foi traçar um panorama da divulgação de segmentos nas demonstrações financeiras das companhias abertas que operam no Brasil, publicadas em 2010, primeiro ano de vigência do CPC 22. Para isso procurou-se identificar como foram definidos e quantos são os segmentos publicados, além de analisar tais resultados em relação a características corporativas da empresa: tamanho, setor de atuação e status de listagem da companhia nos níveis de governança corporativa. Trata-se de pesquisa bibliográfica e documental com foco descritivo. O levantamento dos dados foi realizado em notas explicativas de 81 companhias abertas selecionadas entre as maiores empresas, na edição 2010 da Revista Melhores e Maiores. A análise dos dados foi realizada com estatística descritiva e análise de correlação. Os resultados da pesquisa mostraram que há empresas que não fizeram qualquer referência a informações por segmentos. A definição dos segmentos atendeu predominantemente ao critério de linha de negócios, e 27% das companhias agruparam as atividades em um único segmento. A análise da correlação mostrou que somente o tamanho do ativo apresentou relacionamento significante e positivo com as características de definição e quantidade de segmentos publicados. Constatou-se que há grande heterogeneidade nas estruturas dos relatórios por segmento publicados.

  15. ANÁLISE DO NÍVEL DE EVIDENCIAÇÃO DE INFORMAÇÕES POR SEGMENTO DAS COMPANHIAS BRASILEIRAS LISTADAS NO IBRX-50

    Directory of Open Access Journals (Sweden)

    Taise da Silva de Souza

    2016-12-01

    Full Text Available O objetivo da pesquisa é identificar o nível de evidenciação e variáveis que influenciam a divulgação das informações por segmento das companhias abertas atuantes no mercado brasileiro, nos anos de 2010 a 2014. A amostra final da pesquisa foi formada por 45 companhias que compõem o índice IBrX-50 da BM&FBovespa. Trata-se de uma pesquisa descritiva, com abordagem quantitativa, além de assumir natureza documental. O estudo baseou-se em análises das notas explicativas, e aplicou-se o modelo de regressão com dados em painel. Os resultados apontam uma evolução no nível de divulgação em 57% dos itens. Ao analisar as notas explicativas das empresas da amostra nos quatro anos, verificou-se que 6,7% não apresentaram informações por segmento em 2010, 4,4% em 2011, 2,2% em 2012, 2,2% em 2013 e em 2014 todas as companhias da amostra apresentaram as informações por segmento. Dentre as que apresentaram informações por segmento, 19% das empresas informaram que possuíam apenas um segmento em 2010, 20,9% em 2011, 22,7% em 2012, 25% em 2013 e 26,7% em 2014. Observou-se também que, dentre as empresas com dois ou mais segmentos, as companhias com maior grau de endividamento tendem a ter um maior nível de evidenciação de informações por segmento.

  16. Alterações do segmento posterior na microftalmia: relato de casos Posterior segment changes in microphthalmic eyes: case report

    Directory of Open Access Journals (Sweden)

    Fernando José De Novelli

    2009-10-01

    Full Text Available Microftalmia é a alteração de desenvolvimento caracterizada pela redução do tamanho do bulbo ocular. Pode estar associada a manifestações estruturais do segmento anterior e posterior. As alterações mais comuns do segmento anterior são as opacidades corneanas, o estreitamento e fechamento do ângulo da câmara anterior e a catarata, e as mais frequentes no segmento posterior são a efusão uveal, as dobras de retina, a alteração da vascularização capilar macular, a ausência de depressão foveal e a retinosquise periférica. Este estudo descreve o caso de três pacientes com microftalmo e manifestações no segmento posterior documentadas com tomografia de coerência óptica. O primeiro caso apresentou a síndrome de efusão uveal, com descolamento de coróide e de retina, tratada com cirurgia de esclerectomia parcial nos quatro quadrantes. No segundo caso, havia a dobra retiniana neurossensorial na fóvea e feixe papilomacular em ambos os olhos sem o envolvimento de epitélio pigmentado retiniano e coriocapilar. No terceiro paciente, o microftalmo estava acompanhado de ausência da depressão foveal, cujo principal diagnóstico diferencial é a hipoplasia foveal.Microphthalmos is a developmental ocular disorder defined as a small eyeball. The condition can be associated with abnormalities of anterior and posterior segments. The most common anterior characteristics include corneal opacities, angle-closure and a shallow anterior chamber and cataract. The main findings of posterior segment are uveal effusion, retinal folds, abnormalities of macular capillar vascularization, absence of foveal depression and peripheral retinoschisis. Three patients with microphthalmos were assisted and their OCT features of posterior segment were analyzed. The first case had uveal effusion syndrome, choroidal and retinal detachment treated with parcial sclerectomy at the four quadrants. The other case presented with neurosensory retinal fold at fovea

  17. Avaliação do segmento venoso femoropoplíteo pela ultrassonografia Doppler em pacientes com úlcera varicosa

    OpenAIRE

    Abreu,Jesus Antonio de Carvalho; Pitta,Guilherme Benjamin Brandão; Miranda Júnior,Fausto

    2012-01-01

    CONTEXTO: Como a úlcera é uma grave complicação da insuficiência venosa crônica, é necessário o conhecimento amplo de sua fisiopatologia. A ultrassonografia Doppler venosa é o exame complementar mais adequado, que possibilita o estudo do sistema venoso superficial e profundo, sua anatomia e fisiologia. Trabalhos recentes valorizam o refluxo em Veia Poplítea como importante fator para o desenvolvimento deste quadro clínico. OBJETIVOS: Avaliar o refluxo em segmento venoso femoropoplíteo em paci...

  18. Resposta pressórica após exercício resistido de diferentes segmentos corporais em hipertensos Respuesta presórica después de ejercicio de resistencia de diferentes segmentos corporales en hipertensos Pressure response after resistance exercise for different body segments in hypertensive people

    Directory of Open Access Journals (Sweden)

    Adriana Marques Battagin

    2010-09-01

    Full Text Available FUNDAMENTO: O exercício resistido tem sido atualmente recomendado como componente adjunto do exercício aeróbico no programa de treinamento físico direcionado ao tratamento e controle da hipertensão arterial sistêmica (HAS. Entretanto, o mesmo ainda não tem sido amplamente incorporado na prática clínica, possivelmente pela escassez de evidências disponíveis sobre os limites seguros da resposta pressórica aguda nessa modalidade. OBJETIVO: Investigar o efeito agudo do exercício resistido progressivo, de diferentes segmentos corporais, na resposta pressórica de pacientes com hipertensão arterial sistêmica (HAS controlada. MÉTODOS: Vinte e cinco pacientes (14 mulheres com HAS controlada com medicamentos (64,5 ± 10,8 anos de idade e sedentários, realizaram três visitas para uma sessão de exercício resistido progressivo aleatória, nos seguintes grupos musculares: quadríceps femoral, grande dorsal e bíceps braquial. Medidas de pressão arterial foram obtidas em todas as visitas no repouso, imediatamente após cada série de exercício e após 5 minutos de recuperação. RESULTADOS: Imediatamente após o exercício resistido agudo, houve significante aumento das pressões sistólicas, sem modificações significantes das pressões diastólicas, quando comparadas aos níveis pressóricos de repouso, para todos os grupos musculares e para todas as intensidades avaliadas. Adicionalmente, observou-se maior tendência à elevação da pressão sistólica quando o quadríceps femoral foi exercitado em alta intensidade. CONCLUSÃO: O exercício resistido de diferentes segmentos corporais promoveu aumentos similares e seguros dos níveis de pressão arterial sistólica, embora com tendência a maior resposta desta quando exercitados grandes grupos musculares em cargas elevadas.FUNDAMENTO: El ejercicio de resistencia ha sido actualmente recomendado como componente adjunto del ejercicio aeróbico en el programa de entrenamiento f

  19. New trends in intraocular lens imaging

    Science.gov (United States)

    Millán, María S.; Alba-Bueno, Francisco; Vega, Fidel

    2011-08-01

    As a result of modern technological advances, cataract surgery can be seen as not only a rehabilitative operation, but a customized procedure to compensate for important sources of image degradation in the visual system of a patient, such as defocus and some aberrations. With the development of new materials, instruments and surgical techniques in ophthalmology, great progress has been achieved in the imaging capability of a pseudophakic eye implanted with an intraocular lens (IOL). From the very beginning, optical design has played an essential role in this progress. New IOL designs need, on the one hand, theoretical eye models able to predict optical imaging performance and on the other hand, testing methods, verification through in vitro and in vivo measurements, and clinical validation. The implant of an IOL requires a precise biometry of the eye, a prior calculation from physiological data, and an accurate position inside the eye. Otherwise, the effects of IOL calculation errors or misplacements degrade the image very quickly. The incorporation of wavefront aberrometry into clinical ophthalmology practice has motivated new designs of IOLs to compensate for high order aberrations in some extent. Thus, for instance, IOLs with an aspheric design have the potential to improve optical performance and contrast sensitivity by reducing the positive spherical aberration of human cornea. Monofocal IOLs cause a complete loss of accommodation that requires further correction for either distance or near vision. Multifocal IOLs address this limitation using the principle of simultaneous vision. Some multifocal IOLs include a diffractive zone that covers the aperture in part or totally. Reduced image contrast and undesired visual phenomena, such as halos and glare, have been associated to the performance of multifocal IOLs. Based on a different principle, accommodating IOLs rely on the effort of the ciliary body to increase the effective power of the optical system of the

  20. Retrolaminar Migration of Intraocular Silicone Oil.

    Science.gov (United States)

    Boren, Rance A; Cloy, Carson D; Gupta, Ankur S; Dewan, Vinay N; Hogan, R Nick

    2016-12-01

    Migration of intravitreal silicone to the retrolaminar optic nerve was detected pathologically in 1983, symptomatic migration to the subarachnoid space of the optic nerve was reported in 1994, and asymptomatic intraventricular silicone was first seen radiographically in 1999. Since then, little advance has been made in understanding this phenomenon despite numerous case reports. Although some authors have restricted their attention to cases of intraventricular silicone, we believe that these represent part of a clinical spectrum and that all cases with retrolaminar silicone should be considered. The pathophysiology of silicone migration may have significant implications for the management of patients after vitrectomy. Two patients were evaluated by the authors. An internet-based literature review was conducted, beginning with the key search terms "intraventricular, intracranial, subarachnoid, or optic nerve silicone," and "complications of vitrectomy or intravitreal silicone." Further searches cascaded from the initial search results. An additional 24 cases of retrolaminar migration of silicone oil were found and summarized. The relevant anatomy and pathophysiology were reviewed, with attention to additional information from enucleation studies, as well as to gaps in the current understanding of this process. Retrolaminar migration of silicone oil may be more common than previously thought, especially in at-risk patient groups, and may be associated with visual and neurologic symptoms. Some impressions regarding the cause and significance of this syndrome seem incorrect. Although this process is likely linked to postoperative elevations of intraocular pressure, the exact mechanisms of silicone entry into the subarachnoid space remain undefined. A number of anatomic factors may influence the movement of silicone from the orbit and in the various compartments of the subarachnoid space and ventricular system, resulting in variability of clinical presentations and

  1. Retropupillary iris claw intraocular lens implantation in aphakia for dislocated intraocular lens.

    Science.gov (United States)

    Faria, Mun Yueh; Ferreira, Nuno Pinto; Pinto, Joana Medeiros; Sousa, David Cordeiro; Leal, Ines; Neto, Eliana; Marques-Neves, Carlos

    2016-01-01

    Nowadays, dislocated intraocular lenses (IOLs) and inadequate capsular support are becoming a challenge for every ophthalmic surgeon. Explantation of dislocated IOL and iris claw IOL (ICIOL) are the techniques that have been used in our ophthalmic department. The aim of this study is to report our technique for retropupillar ICIOL. This study is a retrospective case series. A total of 105 eyes with dislocated IOL from the patients at the Department of Ophthalmology in Santa Maria Hospital, a tertiary reference hospital in Lisbon, Portugal, from January 2012 until January 2016, had been analyzed. Of these 105 eyes, 66 eyes had dislocated one-piece IOL and 39 eyes had dislocated three-piece IOL. The latter underwent iris suture of the same IOL and were excluded from this study. The remaining 66 eyes with dislocated one-piece IOL underwent pars plana vitrectomy, that is, explantation of dislocated IOL through corneal incision and an implantation of retropupillary ICIOL. Operative data and postoperative outcomes included best corrected visual acuity, IOL position, intraocular pressure, pigment dispersion, clinical signs of endothelial cell loss, and anterior chamber depth. The mean follow-up was 23 months (range: 6-48 months). The mean preoperative best corrected visual acuity was 1.260±0.771 logMAR, and postoperative best corrected visual acuity was 0.352±0.400 logMAR units. Mean vision gain was 0.909 logMar units. The patients had the following complications: 1) retinal detachment was found in one patient, 2) corneal edema was found in three patients, 3) high intraocular pressure was observed in twelve patients, 4) subluxation of the IOL was observed in one patient, and 5) macular edema was found in three eyes. The results demonstrate that retropupillary ICIOL is an easy and effective method for the correction of aphakia in patients not receiving capsule support. The safety of this procedure must be interpreted in the context of a surgery usually indicated in

  2. Retropupillary iris claw intraocular lens implantation in aphakia for dislocated intraocular lens

    Directory of Open Access Journals (Sweden)

    Faria MY

    2016-08-01

    Full Text Available Mun Yueh Faria,1–3 Nuno Pinto Ferreira,1–3 Joana Medeiros Pinto,1–3 David Cordeiro Sousa,1–3 Ines Leal,1–3 Eliana Neto,1–3 Carlos Marques-Neves1–3 1Centro de Estudos da Visão, Universidade de Lisboa, 2Department of Ophthalmology, Hospital de Santa Maria, 3Faculty of Medicine, University of Lisbon, Lisbon, Portugal Background: Nowadays, dislocated intraocular lenses (IOLs and inadequate capsular support are becoming a challenge for every ophthalmic surgeon. Explantation of dislocated IOL and iris claw IOL (ICIOL are the techniques that have been used in our ophthalmic department. The aim of this study is to report our technique for retropupillar ICIOL.Methods: This study is a retrospective case series. A total of 105 eyes with dislocated IOL from the patients at the Department of Ophthalmology in Santa Maria Hospital, a tertiary reference hospital in Lisbon, Portugal, from January 2012 until January 2016, had been analyzed. Of these 105 eyes, 66 eyes had dislocated one-piece IOL and 39 eyes had dislocated three-piece IOL. The latter underwent iris suture of the same IOL and were excluded from this study. The remaining 66 eyes with dislocated one-piece IOL underwent pars plana vitrectomy, that is, explantation of dislocated IOL through corneal incision and an implantation of retropupillary ICIOL. Operative data and postoperative outcomes included best corrected visual acuity, IOL position, intraocular pressure, pigment dispersion, clinical signs of endothelial cell loss, and anterior chamber depth.Results: The mean follow-up was 23 months (range: 6–48 months. The mean preoperative best corrected visual acuity was 1.260±0.771 logMAR, and postoperative best corrected visual acuity was 0.352±0.400 logMAR units. Mean vision gain was 0.909 logMar units. The patients had the following complications: 1 retinal detachment was found in one patient, 2 corneal edema was found in three patients, 3 high intraocular pressure was observed in

  3. Epithelial Downgrowth after Intraocular Surgery Treated with Intracameral 5-Fluorouracil

    Directory of Open Access Journals (Sweden)

    Nina Ni

    2015-01-01

    Full Text Available Purpose. To present the clinical and histopathologic correlation of two cases of epithelial downgrowth (EDG after prior intraocular surgery. Methods. Observational case reports. Results. We present two cases of EDG occurring after intraocular surgery. In both cases, after two anterior chamber injections of 5-fluorouracil (5FU, the area of EDG initially regressed. In Case 1, a limited area of EDG eventually recurred, and penetrating keratoplasty with cryotherapy was curative. In Case 2, subsequent corneal edema required Descemet-stripping automated endothelial keratoplasty, and the patient remained clinically free of EDG without further treatment. Conclusion. Intracameral 5FU may have a role in the treatment of EDG after intraocular surgery, though its precise utilization and impact remain to be defined.

  4. Intraocular manifestations of mycobacterium tuberculosis: A review of the literature

    Directory of Open Access Journals (Sweden)

    Lauren A. Dalvin

    2017-05-01

    Full Text Available Mycobacterium tuberculosis: is most commonly associated with pulmonary infection. However, tuberculosis (TB can also affect the eye. TB can affect nearly any tissue in the eye, and a high index of suspicion is required for accurate diagnosis, as many of the intraocular manifestations of TB can mimic other, more common diseases. Correct diagnosis is critical because systemic anti-tuberculosis treatment may be required, and vision loss or even loss of the affected eye can occur without proper treatment. Thus, it is important for ophthalmologists and infectious disease specialists to work together to accurately diagnose and treat intraocular TB. This article reports the various known presentations of intraocular TB and reviews important elements of diagnosis and treatment. Keywords: Mycobacterium, Tuberculosis, Choroidal granuloma, Retinal vasculitis

  5. Análise do Comportamento de Compra de Três Segmentos de Consumidores nos Supermercados

    Directory of Open Access Journals (Sweden)

    Sheila Farias Alves Garcia

    2010-06-01

    Full Text Available O ambiente atual caracterizado pelas mudanças estruturais do mercado, pela entrada de concorrentes internacionais e pela concentração do setor, aponta o surgimento de um novo modelo de gestão nas organizações varejistas, pautado pela eficiência e foco no consumidor. Os varejistas devem se adequar ao modelo de criação de valor para os clientes, o que implica conhecer profundamente o consumidor, acompanhando as suas necessidades, mudanças e tendências, com o objetivo de se adaptar às novas exigências do mercado. Nesse contexto, este artigo parte da necessidade, cada vez maior, de compreender e considerar o consumidor, apresentando e analisando o comportamento de três segmentos de consumidores (idosos, sozinhos e mulheres chefes de família, que demonstram, segundo dados do IBGE (2005, um aumento significativo na população (61% nos últimos anos. O objetivo do presente ensaio é investigar o comportamento desses segmentos de consumidores que frequentam supermercados e verificar possíveis estratégias e oportunidades na criação e fortalecimento de um relacionamento de valor com eles, a partir de necessidades distintas. DOI: 10.5585/remark.v9i1.2150

  6. [Implantation of intraocular lenses. Bullous keratopathy in pseudophakos].

    Science.gov (United States)

    Alberth, B

    1982-09-01

    The author presents his views on the implantation of intraocular lenses, in connection with two pseudophakic bullous keratopathy cases. There is no medical indication for implantation. The question is whether the most important function of the eye, object vision, may be risked in order to avoid aniseikonia or to restore binocular vision? Knowing that vision can be restored with glasses or contact lenses, is it ethical to induce more or less severe postoperative complications by means of intraocular lenses? In view of the considerable success often achieved immediately after the operation, complications which may not arise years later should also be taken into consideration.

  7. Bacillus cereus panophthalmitis associated with intraocular gas bubble.

    Science.gov (United States)

    al-Hemidan, A; Byrne-Rhodes, K A; Tabbara, K F

    1989-01-01

    It has become increasingly apparent that Bacillus cereus can cause a severe and devastating form of endophthalmitis following penetrating trauma by a metallic object. B. cereus is an uncommon aetiological agent in non-clostridial gas-forming infections. The patient studied in this single case report showed evidence of intraocular gas mimicking gas gangrene infection. The physiology of non-clostridial bacteria producing gas from anaerobic metabolic conditions is reviewed. Further intraocular and systemic complications which may be avoided by accurate and early diagnosis and the use of recommended treatment with antibiotics such as clindamycin. Images PMID:2493262

  8. Intraocular dapiprazole for the reversal of mydriasis after extracapsular cataract extraction with intraocular lens implantation. Part II: Comparison with acetylcholine.

    Science.gov (United States)

    Ponte, F; Cillino, S; Faranda, F; Casanova, F; Cucco, F

    1991-11-01

    Intraocular dapiprazole for reversing mydriasis during extracapsular cataract extraction with intraocular lens (IOL) implantation has been compared to intraocular acetylcholine. Ninety patients were enrolled in a double-blind study and divided into three groups of 30 eyes; each group received balanced salt solution (control), 0.25% dapiprazole, or 1% acetylcholine. Pupillary diameter recordings were performed immediately before and a few minutes after drug injection, and two, four and eight hours after surgery. Goldmann tonometry was performed the day before and 6 and 24 hours after surgery. Contact endothelial cell count was performed before and one and four months after surgery. The results indicated a slower starting but longer lasting effect with dapiprazole than with acetylcholine and a significant reduction of the postoperative intraoperative pressure rise with both drugs. No significant difference in reduction in the endothelial cell count was seen between dapiprazole and acetylcholine groups and the control group.

  9. Computerized calculation scheme for toric intraocular lenses.

    Science.gov (United States)

    Langenbucher, Achim; Seitz, Berthold

    2004-06-01

    While a number of intraocular lens (IOL) power prediction formulae are well established for determination of spherical lenses, no common strategy has been published for the computation of toric IOLs. The purpose of this study is to describe a paraxial computing scheme for tracing an axial pencil of rays through the 'optical system eye' containing astigmatic refractive surfaces with their axes at random. The capabilities of this computing scheme are demonstrated with clinical examples. Based on a schematic model eye with spherocylindric surfaces, we use two alternative notations for description of vergences or prescriptions: (1) standard notation (refraction in both cardinal meridians and axis), and (2) component notation (spherical equivalent and cylindric component in 0 degrees and 45 degrees. Refractive surfaces are added to the vergence in component notation, whereas the transformation of the vergence through media is performed in the standard notation for both cardinal meridians. For calculation of the toric lens implant, a pencil of rays is traced through the spectacle and the cornea to the estimated lens position as well as backwards from the retina to the estimated lens position. For calculation of residual spectacle refraction, a pencil of rays is traced backwards from the retina through the toric lens implant and the cornea to the spectacle plane. In example 1 we calculate a 'thin toric lens' for compensation of a corneal astigmatism to achieve a spherical target refraction. In example 2 we compute a 'thick toric lens', which has to compensate for an oblique corneal astigmatism and rotate the spectacle cylinder to the against the rule position to enhance near vision. In example 3 we estimate the residual refraction at the corneal plane after implantation of a thick toric lens, when the cylinder of the lens implant is compensating the corneal cylinder in part and the axis of implantation is not fully aligned with the axis of the corneal astigmatism. This

  10. Níveis de PCR são maiores em pacientes com síndrome coronariana aguda e supradesnivelamento do segmento ST do que em pacientes sem supradesnivelamento do segmento ST

    Directory of Open Access Journals (Sweden)

    Syed Shahid Habib

    2011-01-01

    Full Text Available FUNDAMENTO: Há grande interesse no uso de proteína C-reativa de alta sensibilidade (PCR-as para avaliação de risco. Altos níveis de PCR-as no início da síndrome coronária aguda (SCA, antes da necrose tecidual, pode ser um marcador substituto para comorbidades cardiovasculares. OBJETIVO: Dessa forma, nosso objetivo foi estudar diferentes medidas de seguimento de níveis de PCR-as em pacientes com SCA e comparar as diferenças entre infarto do miocárdio sem elevação do segmento ST (NSTEMI com pacientes apresentando elevação do segmento ST (STEMI. MÉTODOS: Este é um estudo observacional. Dos 89 pacientes recrutados, 60 apresentavam infarto agudo do miocárdio (IAM. Três níveis seriados de PCR-us, a nível basal na hospitalização antes de 12 horas após inicio dos sintomas, níveis de pico 36-48 horas após hospitalização e níveis de acompanhamento após 4 a 6 semanas foram analisados e comparados entre pacientes com (IAMCSST e sem supradesnivelamento do segmento ST (IAMSSST. RESULTADOS: Pacientes com IAMCSST tinham IMC significantemente mais alta quando comparados com pacientes IAMSSST. Os níveis de creatino quinase fração MB (CK-MB e aspartato aminotransferase (AST eram significantemente mais altos em pacientes com IAMCSST quando comparados com pacientes com IAMSSST (p<0,05. Os níveis de PCR a nível basal e no acompanhamento não diferiram de forma significante entre os dois grupos (p=0,2152 e p=0,4686 respectivamente. Houve uma diferença significante nos níveis de pico de PCR entre os dois grupos. No grupo de pacientes com IAMCSST os níveis foram significantemente mais altos quando comparados aos pacientes com IAMSSST (p=0,0464. CONCLUSÃO: Pacientes com IAMCSST apresentam picos significantemente mais elevados de PCR quando comparados a pacientes IAMSSST. Esses dados sugerem que o processo inflamatório tem um papel independente na patogênese do infarto do miocárdio. Dessa forma, os níveis de PCR podem ajudar na

  11. Intraocular pressure and visual acuity across the phases of the ...

    African Journals Online (AJOL)

    Context: Available literature suggests that the pattern of variation in intraocular pressure (IOP) in different phases of the menstrual cycle is inconsistent. Results from studies on the effects of oestrogen and progesterone alone or in combination, on IOP have been conflicting. Aim: To determine the pattern of changes in IOP ...

  12. Prevalence of glaucoma suspects and pattern of intra-ocular ...

    African Journals Online (AJOL)

    Background: Glaucoma is the commonest cause of irreversible blindness in the world. Some glaucoma patients start out as glaucoma suspects for years. Aim: To determine the prevalence of glaucoma suspects and pattern of intra-ocular pressure distribution in glaucoma suspects. Methods: This survey was carried out in ...

  13. Comparison of Intraocular Pressure Reduction of Initial and Adjunct ...

    African Journals Online (AJOL)

    baseline, 60 min post procedure, days 1, 7, 30, 90, and 180. Results: Mean ... frequency‑doubled, Q‑switched neodymium yttrium aluminum garnet laser .... Day 90. 3.5. 1.9. Day 180. 2.8. 2.7. IOP: Intraocular pressure, SLT: Selective laser trabeculoplasty. Table 4: Percentage IOP reduction, values in percentage. Initial SLT.

  14. The influence of the tonometer position on canine intraocular ...

    African Journals Online (AJOL)

    The objective of this study was to assess the variability of readings made using the Tonovet® rebound tonometer for measurement of intraocular pressure (IOP) in the peripheral cornea and in angulated positions on the canine corneal surface. Forty-six client-owned dogs admitted for ophthalmic evaluation at the Queen's ...

  15. Investigation of the relationship between intraocular pressure and ...

    African Journals Online (AJOL)

    In a randomized prospective study of volunteers attending Abia State University Optometry Clinic, Uturu, 100 healthy subjects of either sex were enlisted into study, ages 17-39yrs (mean 22-9+2.4) and body weight56to 02kg, in order to establish the association between total body water and intraocular pressure.

  16. Telemedicine in the control of intra-ocular pressure.

    Science.gov (United States)

    Michelson, G; Striebel, W; Prihoda, W; Schmidt, V

    2000-01-01

    Glaucoma is one of the most common causes of blindness in the Western world and a major risk factor is increased intra-ocular pressure. We therefore used telemedicine in its control. Patients measured their intra-ocular pressure several times a day with a portable instrument and the values were then entered into a portable digital assistant. These data were transmitted by a modem to a central server. If the intra-ocular pressure was pathologically high, an email message was automatically sent to the ophthalmologist. The pressure curve, including a statistical analysis, was displayed in an easily readable chart format. Ten patients with glaucoma participated in a trial. Self-tonometry with telemedicine enabled continuous evaluation of the patient by the ophthalmologist. This approach offered the advantage of controlling the treatment remotely. Advantages for the patient were that the measurements were easily done at home under normal conditions, and the patient could control when the measurement and data transmission would be performed. Telemedicine is a cost-effective technique enabling the early diagnosis of pathologically increased intra-ocular pressure.

  17. Comparison of intraocular pressure reduction of initial and adjunct ...

    African Journals Online (AJOL)

    Objective: The objective was to compare the intraocular pressure (IOP) lowering effect of selective laser trabeculoplasty (SLT) as initial and adjunct therapy in primary open angle glaucoma (POAG). Subjects and Methods: Retrospective chart review of POAG patients who had SLT either as initial or adjunct therapy over a ...

  18. Intraocular Pressure Changes During Ramadan Fasting: Effect of ...

    African Journals Online (AJOL)

    Background: Ramadan fasting (RF) alters many systemic milieus. Dehydration from fasting may cause weight loss, while sedentary lifestyle of some Muslims during fasting results in weight gain. RF is associated with low intraocular pressure (IOP). We aim to find out changes in IOP and its relationship to weight changes ...

  19. Cerebral migration of intraocular silicone oil: an MRI study

    DEFF Research Database (Denmark)

    Kiilgaard, Jens Folke; Milea, Dan; Løgager, Vibeke

    2011-01-01

    for retinal detachment. Methods: Nineteen patients included in this study were referred for silicone oil removal after uncomplicated retinal detachment surgery using internal silicone oil tamponade. Patients with a previous history of intraocular silicone oil, glaucoma or optic pit were excluded. After...

  20. Development of a ciliary muscle-driven accommodating intraocular lens

    NARCIS (Netherlands)

    Hermans, Erik A.; Terwee, Thom T.; Koopmans, Steven A.; Dubbelman, Michiel; van der Heijde, Rob G. L.; Heethaar, Rob M.

    2008-01-01

    PURPOSE: To develop a ciliary muscle-driven accommodating intraocular lens (IOL) that has a large and predictable range of variable power as a step toward spectacle independence. SETTING: Department of Physics and Medical Technology, VU University Medical Center, Amsterdam, The Netherlands. METHODS:

  1. Development of a ciliary muscle-driven accommodating intraocular lens

    NARCIS (Netherlands)

    Hermans, E.A.; Terwee, T.T.; Koopmans, S.A.; Dubbelman, M.; van der Heijde, R.G.L.; Heethaar, R.M.

    2008-01-01

    Purpose: To develop a ciliary muscle-driven accommodating intraocular lens (IOL) that has a large and predictable range of variable power as a step toward spectacle independence. Setting: Department of Physics and Medical Technology, VU University Medical Center, Amsterdam, The Netherlands. Methods:

  2. Initial Experience With Posterior Chamber Intraocular Lens Implant ...

    African Journals Online (AJOL)

    The results of extracapsular cataract extraction with posterior chamber intraocular lens implant at the Jos University Teaching Hospital are reviewed. The results suggest that despite lack of facilities to calculate the lens power for emmetropia, the use of a standard lens of about 19.0D will provide a good number of our ...

  3. Short Term Effect of Exercise on Intraocular Pressure of Ocular ...

    African Journals Online (AJOL)

    Aim: Numerous international studies have indicated that several physiological changes can influence the intraocular pressure (IOP) of subjects. In order to assess visual health status through physiological changes, the effects of rest and exercise on IOP were investigated in ocular hypertensive subjects and their ...

  4. Cataract surgery with intraocular lens implantation in children aged ...

    African Journals Online (AJOL)

    Cataract surgery with intraocular lens implantation in children aged 5-15 in local anaesthesia: visual outcomes and complications. ... The mean implanted IOL power was 22.01 ±3.16 D. IOL was succefuly implanted in 54 eyes (87.07%). Eight eyes (9.67%) were left aphakic. Increase in BCVA of 4 logMAR lines and above ...

  5. Metastatic intraocular hemangiopericytoma in a dog | Pucket | Open ...

    African Journals Online (AJOL)

    Open Veterinary Journal ... had been undergoing therapy for a recurrent hemangiopericytoma of the right flank presented to the Kansas State University Ophthalmology service for evaluation of a painful left eye. ... This case report is the first to document intraocular metastasis of hemangiopericytoma in a veterinary patient.

  6. Intraocular inflammation following endotamponade with high-density silicone oil.

    NARCIS (Netherlands)

    Theelen, T.; Tilanus, M.A.D.; Klevering, B.J.

    2004-01-01

    BACKGROUND: The use of a mixture of silicone oil and partially fluorinated alkanes (high-density silicone oil) has recently been suggested as intraocular tamponade in complicated retinal detachment of the inferior quadrants. We describe a series of patients who developed a clinical picture

  7. Unexplained heterochromia. Intraocular foreign body demonstrated by computed tomography.

    Science.gov (United States)

    Barr, C C; Vine, A K; Martonyi, C L

    1984-01-01

    Standard radiographic techniques are often inadequate in demonstrating the presence and location of intraocular foreign bodies. Computerized axial tomography was used to confirm the presence of a metallic foreign body in a patient with heterochromia iridis and suspected ocular siderosis in whom no foreign material was found by conventional examination methods.

  8. Efficacy and safety of intraocular implants: a Meta-analysis

    Directory of Open Access Journals (Sweden)

    Ren-Liang Huang

    2016-07-01

    Full Text Available AIM: To systemically evaluate the clinical efficacy and safety of intraocular implants for vitreous retinal surgery. METHODS: We performed a comprehensive search for studies reporting vitreous surgery with intraocular implants randomized controlled and a retrospective controlled clinical trials from China Hownet(CNKI, Wanfang database, and VIP literature database. Studies obtained from those database were filtered according to the criteria, and data were retrieved from eligible studies for further analysis. Then we performed a meta-analysis to evaluate the efficacy and safety of intraocular implants using comprehensive Meta-analysis software version 2(Biostat, Englewood, NJ.RESULTS: In total 36 studies were recruited for our Meta-analysis, including 5 092 cases. Meta analysis showed: 1regarding the efficacy of repairing the retinal detachment, silicone oil was a better intraocular implants than C3F8(OR=1.76; 95% CI: 1.19-2.60, P=0.0047and SF6(OR= 4.68; 95% CI: 1.48-14.81, P=0.0087; 2regarding the risk of postoperative cataract, silicone oil showed significant higher risk than BBS(OR=3.24; 95% CI: 2.10-4.99, P=1.09 e-7, and C3F8(OR=3.03; 95% CI: 1.50-6.10, P=0.0019; 3regarding the risk of postoperative intraocular pressure, silicone oil showed significant higher risk than BBS(OR=6.74; 95% CI: 3.38-13.41, P=5.67 e-08, and C3F8 also showed a higher risk than BBS(OR=4.79; 95% CI: 2.37-9.68, P=1.29 e-05. In addition, silicone oil showed significant lower risk as compared with heavy silicone oil(OR=0.16; 95% CI: 0.08-0.53, P=0.0026. CONCLUSION: The intraocular implants for the treatment of retinal detachment in vitreous retinal surgery are mainly divided into two major categories, liquid and gas implants. The silicone oil, a major liquid implant, shows higher efficacy in terms of treating retinal detachment than the gas implants. However, the silicone oil is associated with a higher risk of postoperative cataract and intraocular pressure as compared

  9. Phacoemulsification and intraocular lens implantation in patients with oculocutaneous albinism.

    Science.gov (United States)

    Dávila, Pedro J; Ulloa-Padilla, Jan P; Izquierdo, Natalio J

    2017-01-01

    To evaluate the benefits of phacoemulsification and intraocular lens implantation in patients with oculocutaneous albinism (OCA). The charts of 195 patients with OCA who visited a local eye clinic were reviewed. All of these patients had genetic linkage analysis to establish OCA type. Frequencies and Paired t-test analysis were determined. Of the 195 patients, nine (4.6%) underwent clear cornea phacoemulsification with intraocular lens implantation. Seven of the nine patients with OCA had the Hermansky-Pudlak (HPS) type 1; two had OCA type 1. Pre-operative BCVA of all eyes ranged from 1.0 to 2.3 logMAR with a mean of 1.42 logMAR and a standard deviation of 0.41 logMAR. Post-operative BCVA of all eyes ranged from 1.0 to 1.30 logMAR with a mean of 1.04 logMAR and a standard deviation of 0.10 logMAR. BCVA improved after phacoemulsification surgery and intraocular lens implantation (p = 0.002). Pre-operative astigmatism of all eyes ranged from +0.50 to +5.75 with a mean of +2.25 and a standard deviation of +2.40. Post-operative astigmatism of all eyes ranged from +0.50 to +2.00 with a mean of +1.23 and a standard deviation of +0.42. Astigmatism improved after phacoemulsification surgery and intraocular lens implantation (p = 0.05). Nine patients with OCA who underwent phacoemulsification and intraocular lens implant experienced improved visual acuity and reduced astigmatism post-operatively. These results suggest cataract surgery may improve vision and refractive errors, and thus quality of life, in patients with albinism.

  10. [Visual quality comparison after multifocal toric intraocular lens or monofocal toric intraocular lens implantation].

    Science.gov (United States)

    Feng, K; Guo, H K; Zhang, Y L; Wu, Z

    2017-04-11

    Objective: To compare visual quality and satisfaction after multifocal toric intraocular lens (Acrysof IQ Restor toric, ART) and monofocal toric intraocular lens implantation in patients. Methods: It was a prospective nonrandomized Phase Ⅲ clinical trial. Patients with age-related cataract and corneal astigmatism were enrolled and accepted phacoemulsification combined with implantation of intraocular lens (IOL) in Henan Provincial Eye Hospital during March 2013 to December 2014. Fifty-six cases were divided into two groups according to which IOL they chose. ART group included 28 cases (3l eyes) aged from 41.0 to 72.0 years, with an average age of 61.5 years; toric group included 28 cases (33 eyes) aged from 42.0 to 75.0 years, with an average age of 63.5 years. Three months postoperatively, uncorrected distance visual acuity (UDVA) at 5, 70, 40 cm, corrected distance, intermediate, and near visual acuities, defocus curve, residual refractive astigmatism, rotational stability of the IOL, contrast sensitivity and patientsatisfaction were evaluated. All data were processed by statistic package deal SPSS 16.0. Postoperative visual acuity, residual astigmatism, IOL axial rotation and contrast sensitivity were compared by independent samples t test; preoperative and postoperative corneal astigmatism were compared by paired t -test; spectacle independency and halo incidence were processed by χ(2) test; visual satisfaction score was analyzed by Mann-Whitney test. Results: At 3 months postoperatively, in ART group, UDVA was (0.04±0.05), UIVA was (0.24±0.15), UNVA was (0.20±0.24). While in Toric group, UDVA was (0.06±0.04), UIVA was (0.30±0.13), UNVA was (0.47±0.21). There was no significant difference in UDVA between two groups( t= 0.79, P= 0.433). But in ART group, UIVA and UNVA were markedly better than those in Toric group( t= 2.74, P= 0.008; t= 3.45, PART group and 2.50 D (+1.00--1.50 D) in the Toric group. Average postoperative residual astigmatism was (-0.45

  11. Estudio retrospectivo de complicaciones asociadas al aceite de silicona. Experiencia de 5 años en un hospital público del norte de México

    Directory of Open Access Journals (Sweden)

    Edwin Javier Anaya-Pava

    2017-03-01

    Conclusiones: Las complicaciones encontradas con el uso del AS fueron AS emulsionado, hipertensión ocular, erosión corneal y la inflamación crónica del segmento anterior, así como una incidencia de catarata creciente conforme al tiempo transcurrido. La tasa de redesprendimiento después del retiro de AS en nuestro hospital fue de casi una quinta parte de todos los casos.

  12. A tomografia de córnea e segmento anterior na propedêutica do exame complementar na avaliação de ectasia

    Directory of Open Access Journals (Sweden)

    Bruno de Freitas Valbon

    2013-02-01

    Full Text Available Descrevemos a importância da tomografia de córnea e segmento anterior na propedêutica do exame complementar na avaliação de ectasia. Esta descrição da interpretação clínica dos índices da tomografia de córnea e segmento anterior (Pentacam - Oculus, Wetzlar, Germany neste relato de caso, demonstra a relevância de uma nova tecnologia na avaliação da córnea e segmento anterior na suspeita de ceratocone. O diagnóstico de ceratocone foi excluído pela análise dos índices tomográficos de ectasia. Detectou-se assimetria entre os lados nasal e temporal por meio da avaliação do mapa de profundidade de câmara anterior. No exame biomicroscópico sob midríase foi constatado subluxação do cristalino, sendo assim devemos estar atentos não somente aos índices tomográficos corneanos na avaliação do exame complementar e sim analisarmos outros dados importantes oferecidos pela tomografia de córnea e segmento anterior.

  13. A common humoral background of intraocular and arterial blood pressure dysregulation.

    Science.gov (United States)

    Skrzypecki, Janusz; Grabska-Liberek, Iwona; Przybek, Joanna; Ufnal, Marcin

    2018-03-01

    It has been postulated that intraocular pressure, an important glaucoma risk factor, correlates positively with arterial blood pressure (blood pressure). However, results of experimental and clinical studies are often contradictory. It is hypothesized that, in some hypertensive patients, disturbances in intraocular pressure regulation may depend on biological effects of blood borne hormones underlying a particular type of hypertension, rather than on blood pressure level itself. This review compares the effects of hormones on blood pressure and intraocular pressure, in order to identify a hormonal profile of hypertensive patients with an increased risk of intraocular pressure surge. The PUBMED database was searched to identify pre-clinical and clinical studies investigating the role of angiotensin II, vasopressin, adrenaline, noradrenaline, prostaglandins, and gaseous transmitters in the regulation of blood pressure and intraocular pressure. Studies included in the review suggest that intraocular and blood pressures often follow a different pattern of response to the same hormone. For example, vasopressin increases blood pressure, but decreases intraocular pressure. In contrast, high level of nitric oxide decreases blood pressure, but increases intraocular pressure. Arterial hypertension is associated with altered levels of blood borne hormones. Contradicting results of studies on the relationship between arterial hypertension and intraocular pressure might be partially explained by diverse effects of hormones on arterial and intraocular pressures. Further studies are needed to evaluate if hormonal profiling may help to identify glaucoma-prone patients.

  14. USO DEL MÓDULO DE PREDICCIÓN DE ACCIDENTES (CPM DEL IHSDM PARA EVALUACIÓN DE SEGURIDAD EN SEGMENTOS DE CARRETERAS DE DOS CARRILES

    Directory of Open Access Journals (Sweden)

    Yasmín Andrea Pérez-Rojas

    2013-07-01

    Full Text Available The document presents an alternative for the safety evaluation in the segments of highways in Colombia, given the absence of this type of practical in the engineering of Colombian highways. Therefore, it is approached CPM (Crash Prediction Module of the program IHSDM (Interactive Highway Safety Design Model of FHWA (Federal Highway Administration, adopted thoroughly in other countries to assess safety in highways. This way, the description of the main characteristics of the module CPM is presented for the prediction of accidents in segments of highways without considering those happened or related to the intersections. This way, the description of the main characteristics of the module CPM is presented for the prediction of accidents in segments of highways without considering those happened or related to the intersections. Finally, the results obtained by analyzing the CPM module, the algorithms of the prediction pattern, and the methodological proposal will permit obtain an enough database for the use and application of the module in Colombia.

  15. Locally Advanced Basal Cell Carcinoma with Intraocular Invasion

    Directory of Open Access Journals (Sweden)

    Georgi Tchernev

    2018-01-01

    Full Text Available We present a 103 - year - old patient, with duration of complaints of about ten years. The initial complaint had been presented as a small nodule, located on the eyebrow, which subsequently ulcerated and encompassed larger regions of the upper and lower eyelids. For the past three years, the patient also had complaints of a worsening of his vision, without seeking for medical help. Within the dermatological examination, an intraocular and periocular localised tumour was established, characterised by a raised peripheral edge and central ulceration. More careful examination revealed that the bulb was fully consumed. The patient refused further diagnosis and treatment. Advanced basal cell carcinomas with intraocular invasion are rare in general. If the patient refuses surgery, radiotherapy and systemic therapy with modern medications such as Vismodegib or Sonidegib are available as treatment options.

  16. Bilateral Acute Angle-closure after Intraocular Surgery.

    Science.gov (United States)

    Hoskens, Kirsten; Pinto, Luis Abegão; Vandewalle, Evelien; Verdonk, Nancy; Stalmans, Ingeborg

    2014-01-01

    We report the case of a 75-year-old woman who developed an acute bilateral angle-closure associated with choroidal effusion a day after an uneventful cataract surgery. The same patient had undergone a similarly uneventful cataract surgery two weeks before, under the same protocol, with no postoperative complication in the other eye. Medical treatment, including the use of oral sulfamide-related drugs (acetazolamide), topical beta-blockers and steroids led to a gradual decrease in intraocular pressure (IOP) and choroidal effusion. Despite initial reports suggesting a link between sulfamide-exposure and these rare forms of angle-closure, our report would suggest a more complex pathophysiology behind this intriguing phenomenon. How to cite this article: Hoskens K, Pinto LA, Vandewalle E, Verdonk N, Stalmans I. Bilateral Acute Angle-closure after Intraocular Surgery. J Curr Glaucoma Pract 2014;8(3):113-114.

  17. Increased Intraocular Pressure after Extensive Conjunctival Removal: A Case Report

    OpenAIRE

    Lee, Young Rok; Na, Jung Hwa; Kim, Jae Yong; Sung, Kyung Rim

    2013-01-01

    A 50-year-old woman, who had undergone extensive removal of conjunctiva on the right eye for cosmetic purposes at a local clinic 8 months prior to presentation, was referred for uncontrolled intraocular pressure (IOP) elevation (up to 38 mmHg) despite maximal medical treatment. The superior and inferior conjunctival and episcleral vessels were severely engorged and the nasal and temporal bulbar conjunctival areas were covered with an avascular epithelium. Gonioscopic examination revealed an o...

  18. Intravitreal triamcinolone for intraocular inflammation and associated macular edema

    Directory of Open Access Journals (Sweden)

    Steven M Couch

    2008-11-01

    Full Text Available Steven M Couch, Sophie J BakriMayo Clinic Department of Ophthalmology, Mayo Clinic, Rochester, MN, USAAbstract: Triamcinolone acetonide (TA is a corticosteroid that has many uses in the treatment of ocular diseases because of its potent anti-inflammatory and anti-permeability actions. Intraocular inflammation broadly referred to as uveitis can result from several causes, including the immune system and after ophthalmic surgery. One of the most common reasons for vision loss with uveitis is macular edema. TA has been used for many years as an intravitreal injection for the treatment of ocular diseases. Several case control studies have been reported showing the efficacy of TA in the treatment of intraocular inflammation and associated macular edema caused by Behcet’s disease, Vogt-Koyanagi-Harada syndrome, sympathetic ophthalmia and white dot syndromes. It has also been shown efficacious in cases of pars planitis and idiopathic posterior uveitis. Some authors have reported its use in postoperative cystoid macular edema. Many of the studies on the use of TA in controlling intraocular inflammation and concomitant macular edema showed its effect to be transient in many patients requiring reinjection. Complications can arise from intravitreal injection of TA including elevated intraocular pressure and cataract. Rarely, it can be associated with infectious and non-infectious endophthalmitis. TA may be useful as an adjuvant in the treatment of uveitis and its associated macular edema, especially in patients resistant or intolerant to standard treatment.Keywords: triamcinolone acetonide, Behcet’s disease, sympathetic ophthalmia, Vogt-Koyanagi-Harada syndrome, white dot syndromes, uveitis, cataract surgery, macular edema, endophthalmitis

  19. Analysis of phakic before intraocular lens implantation for fundus examination

    OpenAIRE

    Juan Chen; Zhong-Ping Chen; Rui-Ling Zhu

    2014-01-01

    AIM:To investigate the findings of the eyes which were examined preoperatively by three mirror contact lens before the implantation of implantable collamer lens(ICL). To analysis the retinal pathological changes and to explore the clinical analysis of early diagnosis and treatment in retinopathy on fundus examination before operation. METHODS:The retrospective case series study included 127 eyes of 64 patients who underwent phakic intraocular lens implantation were received the fundus examina...

  20. Intraocular lens subluxation in a patient with facial atopic dermatitis.

    Science.gov (United States)

    Yamazaki, S; Nakamura, K; Kurosaka, D

    2001-02-01

    A 66-year-old Japanese man presented with subluxation of a posterior chamber intraocular lens (IOL) caused by a rupture of part of Zinn's zonule but no retinal break 2 years after phacoemulsification with IOL implantation. He had a history of atopic dermatitis since infancy. This case presents a rare ocular complication of scratching and rubbing the face and eyelids because of itching related to atopic dermatitis.

  1. Bilateral spontaneous subluxation of scleral-fixated intraocular lenses.

    Science.gov (United States)

    Assia, Ehud I; Nemet, Arie; Sachs, Dani

    2002-12-01

    Two young men with primary ectopic lenses had intracapsular cataract extraction and scleral fixation of posterior chamber intraocular lenses (PC IOLs) using 10-0 polypropylene sutures tied to the IOL eyelets. Three to 9 years after implantation, spontaneous IOL vertical subluxation occurred in all 4 eyes (5 IOL loops), probably because of suture breakage. Late subluxation of a sutured IOL may occur several years after implantation. Double fixation and thicker sutures should be considered, especially in young patients.

  2. Applications of polymers in intraocular drug delivery systems

    Directory of Open Access Journals (Sweden)

    Ali Mohammed Alhalafi

    2017-01-01

    Full Text Available We are entering a new era of ophthalmic pharmacology where new drugs are rapidly being developed for the treatment of anterior and posterior segment of the eye disease. The pharmacokinetics of drug delivery to the eye remains a very active area of ophthalmic research. Intraocular drug delivery systems allow the release of the drug, bypassing the blood–ocular barrier. The main advantage of these preparations is that they can release the drug over a long time with one single administration. These pharmaceutical systems are of great important in the treatment of the posterior segment diseases, and they can be prepared from biodegradable or nonbiodegradable polymers. Biodegradable polymers have the advantage of disappearing from the site of action after releasing the drug. The majority of intraocular devices are prepared from nonbiodegradable polymers, and they can release controlled amounts of drugs for months. Nonbiodegradable polymers include silicone, polyvinyl alcohol, and ethylene-vinyl acetate. The polymers usually employed to prepare nanoparticles for the topical ophthalmic route are poly (acrylic acid derivatives (polyalquilcyanocrylates, albumin, poly-μ-caprolactone, and chitosan. Dendrimers are a recent class of polymeric materials with unique nanostructure which has been studied to discover their role in the delivery of therapeutics and imaging agents. Hydrogels are polymers that can swell in aqueous solvent system, and they hold the solvents in a swollen cross-linked gel for delivery. This review exhibits the current literature regarding applications of polymers in ophthalmic drug delivery systems including pharmacokinetics, advantages, disadvantages, and indications aimed to obtain successful eye therapy. Method of Literature Search: A systematic literature review was performed using PubMed databases into two steps. The first step was oriented to classification of intraocular polymers implants focusing on their advantages and

  3. Stability of Adrenaline in Irrigating Solution for Intraocular Surgery.

    Science.gov (United States)

    Shibata, Yuuka; Kimura, Yasuhiro; Taogoshi, Takanori; Matsuo, Hiroaki; Kihira, Kenji

    2016-01-01

    Intraocular irrigating solution containing 1 µg/mL adrenaline is widely used during cataract surgery to maintain pupil dilation. Prepared intraocular irrigating solutions are recommended for use within 6 h. After the irrigating solution is admistered for dilution, the adrenaline may become oxidized, and this may result in a decrease in its biological activity. However, the stability of adrenaline in intraocular irrigating solution is not fully understood. The aim of this study was to evaluate the stability of adrenaline in clinically used irrigating solutions of varying pH. Six hours after mixing, the adrenaline percentages remaining were 90.6%±3.7 (pH 7.2), 91.1%±2.2 (pH 7.5), and 65.2%±2.8 (pH 8.0) of the initial concentration. One hour after mixing, the percentages remaining were 97.6%±2.0 (pH 7.2), 97.4%±2.7 (pH 7.5), and 95.6%±3.3 (pH 8.0). The degradation was especially remarkable and time dependent in the solution at pH 8.0. These results indicate that the concentration of adrenaline is decreased after preparation. Moreover, we investigated the influence of sodium bisulfite on adrenaline stability in irrigating solution. The percentage adrenaline remaining at 6 h after mixing in irrigating solution (pH 8.0) containing sodium bisulfite at 0.5 µg/mL (concentration in irrigating solution) or at 500 µg/mL (concentration in the undiluted adrenaline preparation) were 57.5 and 97.3%, respectively. Therefore, the low concentration of sodium bisulfite in the irrigating solution may be a cause of the adrenaline loss. In conclusion, intraocular irrigation solution with adrenaline should be prepared just prior to its use in surgery.

  4. Experimental research on intraocular aqueous flow by PIV method.

    Science.gov (United States)

    Yang, Hongyu; Song, Hongfang; Mei, Xi; Li, Lin; Fu, Xineng; Zhang, Mindi; Liu, Zhicheng

    2013-10-21

    Aqueous humor flows regularly from posterior chamber to anterior chamber, and this flow much involves intraocular pressure, the eye tissue nutrition and metabolism. To visualize and measure the intraocular flow regular pattern of aqueous humor. Intraocular flow in the vitro eyeball is driven to simulate the physiological aqueous humor flow, and the flow field is measured by Particle Image Velocimetry(PIV). Fluorescent particle solution of a certain concentration was infused into the root of Posterior Chamber(PC) of vitro rabbit eye to simulate the generation of aqueous and was drained out at a certain hydrostatic pressure from the angle of Anterior Chamber(AC) to represent the drainage of aqueous. PIV method was used to record and calculate the flow on the midsagittal plane of the eyeball. Velocity vector distribution in AC has been obtained, and the distribution shows symmetry feature to some extent. Fluorescent particle solution first fills the PC as it is continuously infused, then surges into AC through the pupil, flows upwards toward the central cornea, reflecting and scattering, and eventually converges along the inner cornea surface towards the outflow points at the periphery of the eyeball. Velocity values around the pupillary margin are within the range of 0.008-0.012 m/s, which are close to theoretical values of 0.0133 m/s, under the driving rate of 100 μl/min. Flow field of aqueous humor can be measured by PIV method, which makes it possible to study the aqueous humor dynamics by experimental method. Our study provides a basis for experimental research on aqueous humor flow; further, it possibly helps to diagnose and treat eye diseases as shear force damage of ocular tissues and destructions on corneal endothelial cells from the point of intraocular flow field.

  5. Composition of intraocular foreign bodies: experimental study of ultrasonographic presentation

    Directory of Open Access Journals (Sweden)

    Márcio Augusto Nogueira Costa

    2013-02-01

    Full Text Available PURPOSE: To investigate the reliability of ultrasound in determining the size and identify the sonographic features and artifacts generated by intraocular foreign bodies of different materials. METHODS: Experimental study using 36 enucleated porcine eyes. Fragments of nine different compositions (wood, glass, plastic, cardboard, iron, aluminum, lead, powder and concrete and similar dimensions (4 mm were implanted via scleral incision into the vitreous cavity of 36 porcine eyes, four eyes were used for each material. Ultrasound examination was performed in all eyes using the contact technique, conductive gel and 10-MHz transducer (EZScan, Sonomed. RESULTS: Considering the material fragments of gunpowder, lead, concrete, aluminum, wood and glass, the size determined by ultrasound was considered statistically similar to the actual size. The material iron presented ultrasound-determined dimension statistically smaller than its actual size. Cardboard and plastic materials showed ultrasound-determined measurements far greater than the actual. All fragments of intraocular foreign bodies demonstrated hyper-reflective interfaces, irrespective of their composition. Whereas the artifacts generated by different materials, it was found that the materials iron, aluminum and lead showed reverberation of great extent. The material wood showed no reverberation. The length of the reverberation artifact for the materials iron, glass, aluminum and cardboard was lower when compared to other materials. All materials presented posterior shadowing artifact, with the exception of aluminum. CONCLUSION: Ultrasonography was considered a reliable technique to determine the size of intraocular foreign bodies in pigs, with little influence caused by its composition. Ultrasound artifacts generated were considered material-dependent and can assist the examiner to identify the nature of a foreign body of unknown etiology. Ultrasonography aided the surgeon to identify, locate and

  6. A case of Alagille syndrome complicated by intraocular lens subluxation and rhegmatogenous retinal detachment

    Science.gov (United States)

    Fukumoto, Masanori; Ikeda, Tsunehiko; Sugiyama, Tetsuya; Ueki, Mari; Sato, Takaki; Ishizaki, Eisuke

    2013-01-01

    This case report describes a case of Alagille syndrome with developing intraocular lens subluxation and rhegmatogenous retinal detachment 4 years after cataract surgery. A 15-year-old female patient with Alagille syndrome-associated cataracts in both eyes underwent phacoemulsification aspiration and intraocular lens implantation. Four years postoperative, intraocular lens subluxation developed in her left eye. For treatment, extraction of the dislocated intraocular lens, anterior vitrectomy, and intraocular lens fixation was performed. Three weeks later, the patient developed rhegmatogenous retinal detachment, which was well-treated by pars plana vitrectomy. Cataract surgery needs to be performed carefully in patients with Alagille syndrome due to the weakness of the zonule of Zinn. Careful postoperative observation is necessary for patients with Alagille syndrome who have undergone intraocular surgery in order to facilitate early detection of a possible rhegmatogenous retinal detachment. PMID:23898221

  7. Near-infrared transillumination photography of intraocular tumours.

    Science.gov (United States)

    Krohn, Jørgen; Ulltang, Erlend; Kjersem, Bård

    2013-10-01

    To present a technique for near-infrared transillumination imaging of intraocular tumours based on the modifications of a conventional digital slit lamp camera system. The Haag-Streit Photo-Slit Lamp BX 900 (Haag-Streit AG) was used for transillumination photography by gently pressing the tip of the background illumination cable against the surface of the patient's eye. Thus the light from the flash unit was transmitted into the eye, leading to improved illumination and image resolution. The modification for near-infrared photography was done by replacing the original camera with a Canon EOS 30D (Canon Inc) converted by Advanced Camera Services Ltd. In this camera, the infrared blocking filter was exchanged for a 720 nm long-pass filter, so that the near-infrared part of the spectrum was recorded by the sensor. The technique was applied in eight patients: three with anterior choroidal melanoma, three with ciliary body melanoma and two with ocular pigment alterations. The good diagnostic quality of the photographs made it possible to evaluate the exact location and extent of the lesions in relation to pigmented intraocular landmarks such as the ora serrata and ciliary body. The photographic procedure did not lead to any complications. We recommend near-infrared transillumination photography as a supplementary diagnostic tool for the evaluation and documentation of anteriorly located intraocular tumours.

  8. Sustained Release Intraocular Drug Delivery Devices for Treatment of Uveitis

    Directory of Open Access Journals (Sweden)

    Nahid Haghjou

    2011-01-01

    Full Text Available Corticosteroids have been the mainstay of uveitis therapy. When intraocular inflammation is unresponsive to steroids, or steroid related side effects become a concern, steroid-sparing medications may be administered which can be classified into immunosuppressive and immunomodulatory agents. Uveitis treatment can be delivered systemically, topically, periocularly or intraocularly. All of the above mentioned medications can entail significant systemic side effects, particularly if administered for prolonged durations, which may become treatment-limiting. Some medications, particularly hydrophobic compounds, may poorly cross the blood-retinal barrier. Topical medications, which have the least side effects, do not penetrate well into the posterior segment and are unsuitable for posterior uveitis which is often sight-threatening. Intraocular or periocular injections can deliver relatively high doses of drug to the eye with few or no systemic side effects. However, such injections are associated with significant complications and must often be repeated at regular intervals. Compliance with any form of regular medication can be a problem, particularly if its administration is associated with discomfort or if side effects are unpleasant. To overcome the above-mentioned limitations, an increasing number of sustained-release drug delivery devices using different mechanisms and containing a variety of agents have been developed to treat uveitis. This review discusses various current and future sustained-release ophthalmic drug delivery systems for treatment of uveitis.

  9. Bilateral spontaneous dislocation of posterior chamber intraocular lens in a patient with gyrate atrophy

    Directory of Open Access Journals (Sweden)

    Michael Kinori

    2012-01-01

    Full Text Available We report a patient with gyrate atrophy, a rare metabolic disease, who had bilateral late spontaneous posterior dislocation of in-the-bag posterior chamber intraocular lens (PCIOL. He underwent pars plana vitrectomy, PCIOL retrieval and anterior chamber intraocular lens implantation in both eyes. This report may imply that patients with gyrate atrophy are at risk for spontaneous dislocation of intraocular lenses.

  10. Effect of plasma colloid osmotic pressure on intraocular pressure during haemodialysis

    OpenAIRE

    Tokuyama, T.; Ikeda, T.; Sato, K.

    1998-01-01

    BACKGROUND—In a previous case report, it was shown that an increase in plasma colloid osmotic pressure induced by the removal of fluid during haemodialysis was instrumental in decreasing intraocular pressure. The relation between changes in intraocular pressure, plasma osmolarity, plasma colloid osmotic pressure, and body weight before and after haemodialysis is evaluated.
METHODS—Intraocular pressure, plasma osmolarity, plasma colloid osmotic pressure, and body weight were evaluated before a...

  11. Focalizando um segmento específico da rede privada de ensino: escolas particulares de baixo custo

    Directory of Open Access Journals (Sweden)

    Ana Rita Siqueira

    Full Text Available Resumo Com base nos dados do censo escolar do Inep/MEC, este artigo parte da constatação empírica de que, no Brasil da última década, temos assistido a uma expansão contínua da matrícula na escola particular no nível da educação básica, fenômeno que, ao que tudo indica, estaria relacionado com a melhoria das condições econômicas de uma parcela das classes populares no país. No entanto, a literatura sociológica se volta principalmente para aquele segmento da rede privada de ensino que acolhe majoritariamente uma clientela formada pelas elites e pelas frações mais favorecidas das classes médias, desconhecendo a heterogeneidade interna existente no universo mais amplo das instituições privadas, notadamente aquelas que oferecem mensalidades de custo mais baixo e que, portanto, recrutam famílias provenientes de estratos sociais menos abastados. O objetivo da pesquisa foi dar os primeiros passos no sentido de conhecer as características desse segmento da rede particular de ensino. Para tanto, foram investigados dois estabelecimentos de ensino privados da cidade de Contagem, em Minas Gerais. A seleção das escolas foi feita a partir da mensalidade cobrada. Os instrumentos de pesquisa utilizados foram a observação direta do funcionamento do estabelecimento e a entrevista semiestruturada com profissionais da escola e com famílias usuárias. Os resultados evidenciaram a existência de algumas características comuns aos dois casos investigados, a saber: origem e gestão familiares; estrutura física e patrimônio material e pedagógico restritos; recursos humanos marcados pela multifuncionalidade; cuidados especiais com a disciplina e segurança dos alunos; proximidade na interação família-escola.

  12. E-Commerce no Brasil: Se o Segmento é Promissor, Por Que Empresas Atuantes Estão no Vermelho?

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    Adriana Serafim dos Santos

    2015-04-01

    Full Text Available A mudança de perfil dos novos consumidores tem exigido das organizações inovação em suas operações. Nesse contexto, uma nova modalidade de negócios tem modificado o cenário brasileiro, o e-commerce. Este segmento está em pleno crescimento, com projeções elevadas de faturamento (EBIT, 2013. No entanto, um paradoxo tem intrigado pesquisadores da área. Se o segmento é promissor, por que as empresas do ramo têm resultados negativos? Diante disso, o objetivo do estudo foi verificar o que revela a análise das demonstrações contábeis sobre o desempenho econômico-financeiro da B2W Digital (que atua no varejo on-line em comparação com outras empresas classificadas no mesmo setor na BM&FBovespa (atuantes no varejo tradicional. Na plataforma teórica foram discutidos os principais indicadores financeiros e econômicos e apresentado um histórico sobre o e-commerce no Brasil. Posteriormente foi realizada análise documental nas demonstrações contábeis das referidas empresas no período de 2007 a 2012. Foi constatado que as principais causas para o baixo desempenho da B2W Digital no período analisado foram: desequilíbrio na gestão dos prazos médios, ou seja, a organização paga seus fornecedores em prazos bem menores do que recebe de seus clientes, por isso a necessidade de financiar sua operação com recursos onerosos de curto prazo, principalmente empréstimos e antecipações de recebíveis, o que acarreta em despesas com taxas e juros; elevado grau de endividamento; baixa margem bruta, devido ao custo da mercadoria vendida que consome mais de 70% de sua receita líquida; e, finalmente, aumento das despesas operacionais, principalmente em distribuição.

  13. Medición de las Actitudes de los Internautas respecto a la Compra On-Line. Segmentación en Base a Actitudes y Caracterización de los Segmentos Identificados

    Directory of Open Access Journals (Sweden)

    Lidia Andrades Caldito

    2005-03-01

    Full Text Available Internet ha introducido numerosos cambios en el contexto de los negocios, poniendo al alcance de las empresas recursos que posibilitan un mayor acercamiento y un mejor conocimiento de sus clientes actuales y potenciales. En el contexto del comercio electrónico, será primordial para las empresas entender a qué factores responde el comportamiento de los consumidores ya que, dada la especial naturaleza de esta modalidad de compra, cabe esperar que existan diferencias respecto a los modelos de comportamiento tradicionales. En este trabajo abordamos el análisis de los usuarios de Internet, tratando de determinar su predisposición hacia la compra on-line a través de la valoración de las actitudes que manifiestan hacia ella. En base a la estimación efectuada, se propone una segmentación de los individuos, y la caracterización de los segmentos hallados, identificando qué aspectos de la compra electrónica consideran más relevantes a la hora de seleccionar un establecimiento virtual.

  14. Análisis baro-estabilométrico de los integrantes de la patrulla acrobática paracaidista del Ejército del Aire

    OpenAIRE

    Belmonte Albaladejo, Agustín Ángel

    2017-01-01

    El estudio del pie es importante en numerosas disciplinas deportivas, pero aumenta su interés cuando se trata de un equipo deportista de élite, y máxime si nos referimos al paracaidismo deportivo, dada la importancia de este segmento anatómico tiene en su entrenamiento y ejecución deportiva. La Patrulla de Paracaidismo Acrobático del Ejercito del Aire (PAPEA), compite al más alto nivel internacional. Es por este motivo que hemos creído de suma importancia el analizar el pie de sus componentes...

  15. Tlaxcala: entre la modernización y la frontera del retroceso: del Prosperato a la Revolución Mexicana

    OpenAIRE

    Jenny Zapata de la Cruz

    2010-01-01

    El trabajo se divide en tres segmentos: el primero responde a la intervención del Estado en la modernización de Tlaxcala en la última década del siglo XIX; el segundo expone el desgaste de las infraestructuras por el mal uso de los revolucionarios; finalmente se presenta el rumbo de la entidad a partir de los años 20 del siglo XX. Se pretende enfocar: que la modernización en Tlaxcala es un proceso de larga duración dirigida por un Estado “paternalista”; y que las vías de la modernidad progres...

  16. The role of pili in Bacillus cereus intraocular infection.

    Science.gov (United States)

    Callegan, Michelle C; Parkunan, Salai Madhumathi; Randall, C Blake; Coburn, Phillip S; Miller, Frederick C; LaGrow, Austin L; Astley, Roger A; Land, Craig; Oh, So-Young; Schneewind, Olaf

    2017-06-01

    Bacterial endophthalmitis is a potentially blinding intraocular infection. The bacterium Bacillus cereus causes a devastating form of this disease which progresses rapidly, resulting in significant inflammation and loss of vision within a few days. The outer surface of B. cereus incites the intraocular inflammatory response, likely through interactions with innate immune receptors such as TLRs. This study analyzed the role of B. cereus pili, adhesion appendages located on the bacterial surface, in experimental endophthalmitis. To test the hypothesis that the presence of pili contributed to intraocular inflammation and virulence, we analyzed the progress of experimental endophthalmitis in mouse eyes infected with wild type B. cereus (ATCC 14579) or its isogenic pilus-deficient mutant (ΔbcpA-srtD-bcpB or ΔPil). One hundred CFU were injected into the mid-vitreous of one eye of each mouse. Infections were analyzed by quantifying intraocular bacilli and retinal function loss, and by histology from 0 to 12 h postinfection. In vitro growth and hemolytic phenotypes of the infecting strains were also compared. There was no difference in hemolytic activity (1:8 titer), motility, or in vitro growth (p > 0.05, every 2 h, 0-18 h) between wild type B. cereus and the ΔPil mutant. However, infected eyes contained greater numbers of wild type B. cereus than ΔPil during the infection course (p ≤ 0.05, 3-12 h). Eyes infected with wild type B. cereus experienced greater losses in retinal function than eyes infected with the ΔPil mutant, but the differences were not always significant. Eyes infected with ΔPil or wild type B. cereus achieved similar degrees of severe inflammation. The results indicated that the intraocular growth of pilus-deficient B. cereus may have been better controlled, leading to a trend of greater retinal function in eyes infected with the pilus-deficient strain. Although this difference was not enough to significantly alter the severity

  17. Segmentos anátomo-cirúrgicos arteriais do rim de cutia (Dasyprocta prymnolopha Anatomical-surgical arterial segments of the kidney in agouti (Dasyprocta prymnolopha

    Directory of Open Access Journals (Sweden)

    Maria A.M. Carvalho

    2008-05-01

    Full Text Available Foram estudados 20 pares de rins decutias (Dasyprocta prymnolopha Wagler, 1831, com o objetivo de descrever os segmentos anátomo-cirúrgicos arteriais. As artérias renais foram injetadas com solução de Vinilite corada, e os rins foram submetidos à corrosão ácida para a obtenção dos moldes vasculares. Observou-se que as artérias renais da cutia, sempre únicas, dividiram-se em artéria setorial ventral e artéria setorial dorsal, caracterizando dois setores renais separados por plano avascular. As artérias setoriais penetraram no hilo renal (100% dos casos. Estes vasos deram origem aos ramos segmentares responsáveis pela irrigação de territórios independentes em cada setor, os segmentos arteriais renais. No rim direito foram observados 3 (60%, 4 (35% e 5 segmentos (5% no setor arterial ventral e 3 (30%, 4 (45%, 5 (20% e 6 (5% segmentos no setor dorsal e, à esquerda, 2(10%, 3 (55% e 4 (35% segmentos no setor ventral e 3 (25%, 4 (50% e 5 (25% no dorsal. Com base na distribuição arterial nos rins de cutia, observaram-se setores e segmentos arteriais independentes, sendo possível, desta forma, a realização de setoriectomia e segmentectomia nesta espécie.Twenty pairs of agouti (Dasyprocta prymnolopha Wagler, 1831 kidneys were studied to describe the arterial anatomical-surgical segments. The renal arteries were injected with stained acetate vinyl, followed by procedures of acid corrosion in order to obtain vascular casts. It was found that the renal artery is always single and bifurcated into ventral and dorsal sectorial arteries. The sectorial arteries reached the kidneys (100% of the cases through the hilus. These vessels gave origin to segmental branches responsible for kidney irrigation. At the right kidney, the ventral sectorial arteries gave origin to 3 (60% of the cases, 4 (35% and 5 (5% segmental branches; the dorsal sectorial arteries gave origin to 3 (30%, 4 (45%, 5 (20% and 6 (5% segmental arteries separated by a

  18. Clinical study on the incidence of vancomycin intraocular injection in treatment with suppurative endophthalmitis

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    Yi-Qin Duan

    2015-05-01

    Full Text Available AIM:To estimate the clinical significance of the microculture of humor and vitreous and vancomycin intraocular injection in treatment of suppurative endophthalmitis associated with intraocular foreign bodies.METHODS: Totally 65 patients with penetrating eye trauma and retained intraocular foreign bodies in emergency operation and intraocular injection from January 2012 to September 2014 were regarded as the study group, another 62 patients with penetrating eye trauma and retained intraocular foreign bodies in emergency operation without intraocular injection before August 2011 were regarded as the control group. Aqueous humor and vitreous humor were taken from each patient of the study group and the control group for bacteria and fungus cultivation. The study group was treated with 1mg vancomycin intraocular injection after operation, while the control group was not. RESULTS: The incidence of endophthalmitis in the control group was 16%(10 cases, while in the study group was 3%(2 cases, with significant difference between two groups(x2=6.32, PP>0.05. The positive rate of vitreous humor germiculture in study group was 14%(9 cases, and the incidence of endophthalmitis was 3%. The positive rate of vitreous humor germiculture in control group was 11%(7 casesand the incidence of endophthalmitis was 16%, with significant differences between two groups(PCONCLUSION: Intraocular foreign bodies treated with emergency operation and vancomycin intraocular injections can decrease the incidence of suppurative endophthalmitis and have a good vision prognosis for the second stage of operation.

  19. INTELIGENCIA COMPETITIVA: PROPUESTA DE MODELO SISTEMICO COMO CAMBIO ORGANIZACIONAL PARA LOS HOSPITALES DEL SUR DEL BRASIL

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    Nilda, Tañski

    2011-01-01

    Full Text Available El éxito de una organización depende cada vez más, de la estrategia de su negocio. Un componente estructural de la estrategia es el ajuste entre sus actividades primarias y sus actividades de soporte. Y así como en la industria, en un hospital, una nueva estrategia para ser implementada en general implica revisar procesos de negocios o introducir nuevas formas de ejecutar las operaciones de la empresa. Sin embargo, organizaciones que tengan problemas de alienación entre la estrategia de negocios con su infraestructura de Tecnología de Información tendrán dificultades de implantar un modelo sistémico del proceso de inteligencia competitiva. Se cree que el segmento hospitalario privado tiene problemas de sincronismo entre la estrategia de negocios con la infraestructura de Tecnología de la Información (TI. Por lo tanto, se puede cuestionar: ¿Un modelo sistémico de Inteligencia Competitiva para el segmento hospitalario privado, puede ser un modelo conceptual del proceso de cambio, pasible de ser implementado en este tipo de organización? El objetivo principal de este trabajo de investigación es proponer un Modelo Sistémico del proceso de Inteligencia Competitiva versión 2, en los hospitales privados de la región sur de Brasil.

  20. Comparison of Two Intraocular Lens Implantation Techniques in Pediatric Cataract Surgery in Terms of Postoperative Complications

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    Mustafa Erdoğan Cicik

    2018-03-01

    Full Text Available Background: Pediatric cataract surgery differs substantially from adult cataract surgery. Numerous studies have focused on reducing the development of postoperative complications. Aims: To compare two intraocular lens implantation techniques used in pediatric cataract surgery in terms of postoperative complications. Study Design: Case-control study. Methods: Patients who underwent pediatric cataract surgery and intraocular lens implantation between 2008 and 2016 were evaluated in this retrospective study. Patients aged 3-15 years with unilateral or bilateral cataract and without corneal pathology were included in the study. The patients were categorized into the following two groups: those who underwent posterior capsulorhexis and anterior vitrectomy using in-the-bag intraocular lens implantation (group 1 and those who underwent posterior capsulorhexis and intraocular lens implantation with the optic fixed behind the posterior capsulorhexis (group 2. Rates of postoperative visual axis opacification and complications (glaucoma, posterior synechiae, uveitic reaction, and intraocular lens decentration were evaluated in these groups. The implanted intraocular lenses were either monoblock (AcrySof SN60AT intraocular lens, triple-piece (AcrySof MA60BM intraocular lens foldable hydrophobic acrylic lenses, or multifocal lenses (AcrySof IQ ReSTOR. Results: This retrospective study included 52 eyes of 37 patients. Group 1 comprised 26 eyes of 20 patients and group 2 comprised 26 eyes of 17 patients. During the follow-up, visual axis opacification was observed in two patients in group 1 but no patients in group 2. Regarding postoperative complications, there was no uveitic reaction, posterior synechiae, or intraocular lens decentration in either group. There was no significant difference between the groups in terms of the postoperative complications (p>0.05. Conclusion: There was no significant difference between in-the-bag intraocular lens implantation

  1. Principales métodos para el cálculo de la lente intraocular después de la cirugía refractiva corneal

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    Taimí Cárdenas Díaz

    Full Text Available Con el surgimiento y el desarrollo de la cirugía refractiva corneal se han podido corregir quirúrgicamente a millones de pacientes con defectos refractivos. Con el cursar de los años comienza a opacarse fisiológicamente el cristalino, y disminuye la agudeza visual en estos pacientes a quienes se les modificó la curvatura corneal. Ante la necesidad de remover el cristalino y de calcular una lente intraocular de potencia adecuada para conseguir la emetropía, surge un nuevo reto a la Oftalmología. El cálculo de la lente intraocular en pacientes con cirugía refractiva corneal es mucho más complejo, pues además de tener longitudes axiales extremas, se añaden factores por la intervención previa que alteran la predictibilidad del resultado visual, con la aplicación de las fórmulas de cálculo de lente intraocular existentes. Se han descrito varios métodos que permiten determinar correctamente la potencia de la lente a implantar, dependiendo de los datos de los que se dispongan; de ahí la motivación para realizar una revisión de diferentes publicaciones con el propósito de describir los principales métodos empleados para realizar el cálculo de la lente intraocular en estos pacientes. Se utilizó la plataforma Infomed, específicamente la Biblioteca Virtual de Salud, con todos sus buscadores.

  2. UV solid state laser ablation of intraocular lenses

    Science.gov (United States)

    Apostolopoulos, A.; Lagiou, D. P.; Evangelatos, Ch.; Spyratou, E.; Bacharis, C.; Makropoulou, M.; Serafetinides, A. A.

    2013-06-01

    Commercially available intraocular lenses (IOLs) are manufactured from silicone and acrylic, both rigid (e.g. PMMA) and foldable (hydrophobic or hydrophilic acrylic biomaterials), behaving different mechanical and optical properties. Recently, the use of apodizing technology to design new diffractive-refractive multifocals improved the refractive outcome of these intraocular lenses, providing good distant and near vision. There is also a major ongoing effort to refine laser refractive surgery to correct other defects besides conventional refractive errors. Using phakic IOLs to treat high myopia potentially provides better predictability and optical quality than corneal-based refractive surgery. The aim of this work was to investigate the effect of laser ablation on IOL surface shaping, by drilling circular arrays of holes, with a homemade motorized rotation stage, and scattered holes on the polymer surface. In material science, the most popular lasers used for polymer machining are the UV lasers, and, therefore, we tried in this work the 3rd and the 5th harmonic of a Q-switched Nd:YAG laser (λ=355 nm and λ=213 nm respectively). The morphology of the ablated IOL surface was examined with a scanning electron microscope (SEM, Fei - Innova Nanoscope) at various laser parameters. Quantitative measurements were performed with a contact profilometer (Dektak-150), in which a mechanical stylus scanned across the surface of gold-coated IOLs (after SEM imaging) to measure variations in surface height and, finally, the ablation rates were also mathematically simulated for depicting the possible laser ablation mechanism(s). The experimental results and the theoretical modelling of UV laser interaction with polymeric IOLs are discussed in relation with the physical (optical, mechanical and thermal) properties of the material, in addition to laser radiation parameters (laser energy fluence, number of pulses). The qualitative aspects of laser ablation at λ=213 nm reveal a

  3. INTRAOCULAR AND SERUM LEVELS OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN ACUTE RETINAL NECROSIS AND OCULAR TOXOPLASMOSIS

    NARCIS (Netherlands)

    Wiertz, Karin; De Visser, Lenneke; Rijkers, Ger; De Groot-Mijnes, Jolanda; Los, Leonie; Rothova, Aniki

    2010-01-01

    Purpose: To determine the intraocular and serum vascular endothelial growth factor (VEGF) levels in patients with acute retinal necrosis (ARN) and compare those with VEGF levels found in patients with ocular toxoplasmosis (OT). Methods: Paired intraocular fluid and serum samples of 17 patients with

  4. [Scheimpflug photography for the examination of phakic intraocular lenses].

    Science.gov (United States)

    Baumeister, M

    2014-10-01

    High myopia phakic intraocular lenses (IOL) have become an established means of surgical correction for high ametropia. Scheimpflug photography is one of the methods which are frequently applied for postoperative examination of the implants. Results from published studies employing Scheimpflug photography for examination of anterior chamber angle-fixated, iris-fixated and sulcus-fixated phakic IOLs were evaluated. In several published studies Scheimpflug photography was used to examine the position of the implant and opacification of the crystalline lens. The results provided valuable evidence for the improvement of phakic IOL design. Scheimpflug photography offers an easy to use, rapid non-contact examination of phakic IOLs.

  5. Sectioning a luxated intraocular lens inside the vitreous cavity.

    Science.gov (United States)

    Vilaplana, Daniel; Pazos, Marta

    2013-07-01

    We describe a new technique for sectioning an intraocular lens (IOL) inside the vitreous cavity. The IOL had a broken haptic and was accidentally luxated after a complicated cataract surgery with posterior capsule rupture. The primary indication to cut the IOL in half inside the vitreous cavity is to preserve the anterior capsule integrity, especially in a small-sized capsulotomy, allowing subsequent implantation of a new IOL in the sulcus with the optical zone captured in the capsulorhexis. Neither author has a financial or proprietary interest in any material or method mentioned. Copyright © 2013 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  6. [Cataract extraction with intraocular lenses in a teaching hospital].

    Science.gov (United States)

    Jara, R; Charlín, R; Schweikart, A; Stoppel, J; Maul, E

    1991-07-01

    One hundred and twelve primary posterior chamber intraocular lens implants from a series of 560 eyes operated on at the Eye Service of Hospital Salvador in Santiago, Chile, were analyzed to determine the postoperative visual acuity. The follow up time varied between 3 and 26 months. Lenses were implanted by experienced ophthalmologists and residents in training. Visual acuity was 0.5 or better in 79.5% of cases. The postoperative visual acuity varied with age, being worse in patients over 70 years old.

  7. Comparison of Contrast Sensitivity and Through Focus in Small-Aperture Inlay, Accommodating Intraocular Lens, or Multifocal Intraocular Lens Subjects.

    Science.gov (United States)

    Vilupuru, Srividhya; Lin, Ling; Pepose, Jay S

    2015-07-01

    To compare monocular and binocular mesopic contrast sensitivity and through focus following monocular implantation with KAMRA small-aperture inlay (AcuFocus, Irvine, California, USA) vs binocular implantation with an accommodating or multifocal intraocular lens (IOL) implant. Three-treatment randomized clinical trial of presbyopia-correcting IOLs with comparison to results from a previous nonrandomized multicenter clinical trial on the KAMRA corneal inlay. Study population of 507 subjects with KAMRA inlays; predetermined subgroups included 327 subjects that underwent contrast sensitivity testing and another 114 subjects for defocus curve testing, along with 78 subjects randomized between bilateral Crystalens Advanced Optics (AO) (Bausch + Lomb Surgical, Aliso Viejo, California, USA), AcrySof IQ ReSTOR +3.0 D (Alcon Laboratories, Fort Worth, Texas, USA), or Tecnis +4D Multifocal (MF) (Abbott Medical Optics, Santa Ana, California, USA) IOL. KAMRA inlay subjects demonstrated improved intermediate and near vision with minimal to no change to distance vision, better contrast sensitivity in the inlay eye when compared to the multifocals, and better binocular contrast sensitivity when compared to all 3 intraocular lenses. Crystalens AO was superior in uncorrected intermediate vision compared to the KAMRA inlay, but not in distance-corrected intermediate, and was worse in near vision. The multifocals were superior in near vision at their respective optimum near focus points, but worse in intermediate vision compared to both KAMRA inlay and Crystalens AO. The demonstrated performance of these devices should be considered, along with subjects' visual demands and expectations, degree of crystalline lens dysfunction, and other ocular characteristics, in guiding the selection of small-aperture corneal inlay or specific intraocular lens in the correction of presbyopia. Copyright © 2015 Elsevier Inc. All rights reserved.

  8. Empresas brasileiras do novo mercado e suas práticas de evidenciação voluntária de informações por segmento

    Directory of Open Access Journals (Sweden)

    Ana Paula Capuano da Cruz

    2014-05-01

    Full Text Available A adoção das normas internacionais de contabilidade tem demandado alterações no padrão contábil de diversos países. Dentre tais mudanças, no Brasil, tem-se a incorporação de uma prática de divulgação de resultados que exige a evidenciação de informações por segmentos. O segment reporting, como também é denominado, é uma exigência introduzida pela International Financial Reporting Standard (IFRS 8 que implica um ponto de tangência muito forte entre a contabilidade gerencial e a contabilidade com foco no usuário externo. Com base nessas alterações, a partir da análise das Notas Explicativas das 106 companhias listadas no Novo Mercado da Bolsa de Valores, Mercadorias e Futuros de São Paulo (BM&FBovespa, o estudo objetivou verificar como as companhias abertas brasileiras estruturaram o formato de evidenciação de informações por segmento. Em termos metodológicos, trata-se de uma pesquisa documental, de caráter descritivo, que conjuntou o emprego da técnica de análise de conteúdo e de testes não paramétricos de Mann-Whitney e Kruskal-Wallis para verificar o grau de intensidade da divulgação de informações por segmento, conforme metodologia utilizada por Guthrie et al. (1999. Os achados sinalizaram que a divulgação voluntária de informações por segmento ainda é incipiente no cenário brasileiro. Identificou-se que as companhias auditadas por uma das Big Four apresentaram menor grau de intensidade na divulgação dos impactos futuros da aplicação das orientações normativas sobre informações por segmento. Considerando o universo das 106 companhias analisadas, destaca-se que as informações segmentadas por área geográfica e ainda, por tipo de produtos ou serviços, mostraram-se mais recorrentes; informações por clientes foram escassas. Nenhuma empresa evidenciou o fluxo de caixa por segmento, e 39 companhias não mencionaram que o CPC 22 trará impacto às futuras Demonstrações Contábeis. Assim

  9. Intraocular pressure in very low birth weight preterm infants and its association with postconceptional age

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    Rodrigo L. Lindenmeyer

    2012-11-01

    Full Text Available OBJECTIVE: To evaluate intraocular pressure in very low birth weight preterm infants and correlate it with postconceptional age. METHODS: The intraocular pressure in a prospective cohort of very low birth weight premature infants (defined as a birth weight <1,500 g and gestational age <32 weeks admitted to Hospital de Clínicas de Porto Alegre , Brazil was evaluated weekly. The evaluated outcome was the variation in the intraocular pressure following changes in the postconceptional age (defined as the gestational age at birth plus the age in weeks at the time of examination in the weeks following preterm birth. Mixed-effects models were used for the statistical analysis to determine the intraocular pressure variation according to postconceptional age, and means and 10th and 90th percentiles were calculated for the intraocular pressure values. RESULTS: Fifty preterm infants with a mean gestational age of 29.7 ± 1.6 weeks and a mean birth weight of 1,127.7 ± 222.7 g were evaluated. The mean intraocular pressure for the entire cohort considering both eyes was 14.9 ± 4.5 mmHg, and 13.5% of all recorded intraocular pressure values were greater than 20 mmHg. The analysis revealed a mean reduction in the intraocular pressure of 0.29 mmHg for each increase in postconceptional age (p = 0.047; 95% CI: -0.58 to -0.0035. The mean intraocular pressure (P10-P90 decreased from 16.3 mmHg (10.5222.16 at 26.3 weeks to 13.1 mmHg (7.28-18.92 at 37.6 weeks of postconceptional age. CONCLUSIONS: The mean intraocular pressure in very low birth weight preterm infants was 14.9 ± 4.5 mmHg. This value decreased 0.29 mmHg per week as the postconceptional age increased.

  10. Effect of hemodialysis on intraocular lens power calculation.

    Science.gov (United States)

    Çalışkan, Sinan; Çelikay, Osman; Biçer, Tolga; Aylı, Mehmet Deniz; Gürdal, Canan

    2016-01-01

    To evaluate changes in ocular biometric parameters after hemodialysis (HD) in patients with end-stage renal disease (ESRD). Forty eyes of 40 patients undergoing HD were included in this cross-sectional study. Keratometry (K) readings, white-to-white (WTW) distance, central corneal thickness (CCT), anterior chamber depth (ACD), pupil diameter, lens thickness (LT), axial length (AL), and intraocular lens (IOL) power calculation were measured with Lenstar LS 900 (Haag Streit AG, Koeniz, Switzerland) before and after hemodialysis. Intraocular pressure (IOP) was measured with a non-contact tonometer (Tonopachy NT-530P, Nidek Co., LTD, Tokyo, Japan). Main outcomes were changes in biometric parameters after HD. Reliability of the measurements (intraclass correlation coefficients (ICCs)) and the effect size (Cohen's d) were also calculated. Mean difference in AL before and after HD was -0.041 ± 0.022 mm with ICCs > 0.90 (p  0.90 (p = 0.041 and Cohen's d = 0.20). Hemodialysis had no significant effect on K readings, WTW distance, CCT, ACD, LT, or IOP. Axial length and pupil diameter increase after HD with small effect size, while HD does not significantly affect IOL power calculations.

  11. Multifocal Toric Intraocular Lens for Traumatic Cataract in a Child

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    Yanfeng Zeng

    2016-10-01

    Full Text Available A child suffering from traumatic cataract and corneal astigmatism of 2.14 D had a phacoemulsification operation and implantation of a ReSTOR Toric intraocular lens (IOL to correct the astigmatism. The primary outcome measurements were the uncorrected distance visual acuity (UDVA, uncorrected near vision at 40 cm, intraocular pressure, spherical equivalent refraction, residual astigmatism, corneal astigmatism, presence of unusual optical phenomena, and use of spectacles. At 7 months postoperatively, UDVA was maintained between 16/20 and 24/20, near vision was between J1 and J3, residual spherical refraction was 0–0.37 D, and residual refractive cylinder was between 0 and 0.67 D. A multifocal toric IOL can provide the possibility of satisfactory vision for both distant and near conditions without the use of spectacles to meet children’s needs when studying and doing sports. Additionally, binocular vision can be reconstructed. This intervention, therefore, seems to be a satisfactory alternative.

  12. Intraocular lenses and clinical treatment in paediatric cataract

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    Camila Ribeiro Koch Pena

    2015-06-01

    Full Text Available Pediatric cataract is the most common treatable cause of blindness in children. Prevalence, etiology and morphology vary with the socioeconomic development. The treatment goal is to reduce amblyopia, being difficult management especially in unilateral cases. The decision on aphakia or primary intraocular lens should be individualized as well as correction with contact lens or spectacles. The intraocular lens single-piece hydrophobic acrylic are the most implanted in children and the preferably is in the capsular bag. The Sanders-Retzlaff-Kraff theoretic (SRK/T stressing that is described as more predictable, following Holladay I and SRK II and the recommendation is to under correction +6.0 or +8.0 dioptrias expecting the growth of the eye. The posterior capsule opacity is the most frequent complication and varies with the material choice of the lens. Glaucoma is the most serious postoperative complication and depends on the timing of the surgery, primary lens implantation and time of post surgical follow-up. The adherence to occlusion therapy with patching is critical to the visual prognosis and is determined by the child’s age and laterality of the cataract. There was significant improvement in the surgery and in IOLs, however the final visual prognosis is still not desirable.

  13. Clinical observation of four-fixable intraocular lens suspensory

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    Yu-Ming Teng

    2015-06-01

    Full Text Available AIM: To discuss the four-fixable intraocular lens(IOLsuspensory in the absence of capsular intraocular lens implantation, suspensory ligament rupture caused by congenital dislocation of the lens, traumatic cataract and posterior capsular rupture without capsular support, which need to line hanging IOL for intraoperative clinical observation.METHODS: The 31 cases(32 eyeswho were accepted the four-fixable IOL suspensory from May 2012 to May 2014 in our hospital were retrospectively analyzed. The postoperative visual acuity, corneal astigmatism, intraoperative and postoperative complications were comprehensively analyzed.RESULTS: Patients were followed up 6mo~1a, corrected visual acuity >0.5(12 eyes, 38%, 0.1~0.5(18 eyes, 56%, and CONCLUSION: It is designed to support non-capsular IOL implantation and design, and the concept of changing the past presence of suspended dislocated IOL implantation surgery, positional deviation and, sutures and other complications split the incidence is greatly reduced. It is consistent with the physiological characteristics of the human eye, and it is the IOL surgical sling best stability, intraoperative and postoperative complications, the best visual acuity and corneal astigmatism minimal surgical approachat least, and the four-point suspension suture fixation of IOL is designed to obtain a practical transformation of Chinese patent.

  14. Jóvenes rurales argentinos : análisis del Proyecto Jóvenes Emprendedores Rurales como acción pública : su implementación en la provincia de San Juan

    OpenAIRE

    Di Filippo, María Sol

    2010-01-01

    El trabajo indaga en las principales características de los jóvenes rurales argentinos, y la forma en que las políticas públicas orientan su acción hacia este segmento poblacional. Consta de dos ejes temáticos abordados con metodología cuali-cuantitativa: 1)principales características de la juventud rural argentina; 2) análisis del Proyecto Jóvenes Emprendedores Rurales como política pública nacional de Desarrollo Rural, dirigida a este segmento poblacional, tomando como caso su implementació...

  15. A new device to noninvasively estimate the intraocular pressure produced during ocular compression

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    Korenfeld MS

    2016-01-01

    Full Text Available Michael S Korenfeld,1,2 David K Dueker3 1Comprehensive Eye Care, Ltd., 2Department of Ophthalmology and Visual Sciences, Washington University, Washington, MO, USA; 3Hamad Medical Corporation, Doha, Qatar Purpose: To describe a noninvasive instrument that estimates intraocular pressure during episodes of external globe compression and to demonstrate the accuracy and reliability of this device by comparing it to the intraocular pressures simultaneously and manometrically measured in cannulated eyes. Methods: A thin fluid-filled bladder was constructed from flexible and inelastic plastic sheeting and was connected to a pressure transducer with high pressure tubing. The output of the pressure transducer was sent to an amplifier and recorded. This device was validated by measuring induced pressure in the fluid-filled bladder while digital pressure was applied to one surface, and the other surface was placed directly against a human cadaver eye or in vivo pig eye. The human cadaver and in vivo pig eyes were each cannulated to provide a manometric intraocular pressure control. Results: The measurements obtained with the newly described device were within ~5% of simultaneously measured manometric intraocular pressures in both a human cadaver and in vivo pig eye model for a pressure range of ~15–100 mmHg. Conclusion: This novel noninvasive device is useful for estimating the intraocular pressure transients induced during any form of external globe compression; this is a clinical setting where no other devices can be used to estimate intraocular pressure. Keywords: glaucoma, intraocular pressure, tonometer, ocular compression

  16. Survey of Intraocular Antibiotics Prophylaxis Practice after Open Globe Injury in China.

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    Bingsheng Lou

    Full Text Available To elucidate the Chinese practice of intraocular antibiotics administration for prophylaxis after open globe injury.A cross-sectional questionnaire survey was performed online by scanning a Quickmark (QR code with smartphones at the 20th Chinese National Conference of Ocular Trauma in November 2014.A total of 153 (30.6% of all participators at the conference responded. Of the respondents, 20.9% were routinely administered with prophylactic intraocular injection of antibiotics at the conclusion of the primary eye repair, and 56.9% were used only in cases with high risk of endophthalmitis development. The intraocular route of delivery was mainly included with intracameral injection (47.9% and intravitreal injection (42.0%. Cephalosporins (53.8% and vancomycin (42.0% were the main choices of antibiotic agents, followed by fluoroquinolones (24.3%, and aminoglycosides (13.4%. Only 21.9% preferred a combination of two or more two drugs routinely. In addition, significantly more respondents from the referral eye hospital (92.7% replied using intraocular antibiotics injection for prophylaxis compared to those respondents from the primary hospital (69.4% (p = 0.001, Fisher's exact test.Intraocular antibiotics injection for post-traumatic endophthalmitis prophylaxis is widely used in China. However, the choice of antibiotic agents and the intraocular route of delivery vary. A well-designed clinical trial is needed to establish a standardized protocol of intraocular antibiotics administration for post-traumatic endophthalmitis prophylaxis.

  17. Phakic iris-claw intraocular lens implantation for correction of high myopia with clear corneal incision

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    Lin Li

    2014-04-01

    Full Text Available AIM: To investigate the safety and therapeutic effectiveness of phakic iris-claw intraocular lens implantation for correction of high myopia with clear corneal incision. METHODS: Implantation of phakic iris-claw intraocular lens through clear corneal incision was performed on 28 eyes of 20 high myopic patients under topical anaesthesia. Intraoperative and postoperative complications, visual acuity, intraocular pressure, refractive diopter, corneal endothelium, the stable of intraocular lens and the turbid level of lens were observed. RESULTS: All cases were smoothly implanted iris-claw intraocular lens. No complications were found during the operation. The uncorrected visual acuity of post-operation was better than the best corrected visual acuity of pre-operation. The follow-up time lasted for 6mo, and the intraocular lens in all the eyes were basically in the normal position without tilting and obvious deviation. No serious complications such as cataract, uveitis, cystoid macular edema, retinal detachment were seen in all cases. CONCLUSION: On the basis of having adept microsurgery technology, phakic iris-claw intraocular lens implantation is predictable and stable, and post-operation visual acuity is satisfying with few complications. It is a safe and effective way to treat high myopia.

  18. Change in Intraocular Pressure During Point-of-Care Ultrasound

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    Berg, Cameron

    2015-03-01

    Full Text Available Introduction: Point-of-care ocular ultrasound (US is a valuable tool for the evaluation of traumatic ocular injuries. Conventionally, any maneuver that may increase intraocular pressure (IOP is relatively contraindicated in the setting of globe rupture. Some authors have cautioned against the use of US in these scenarios because of a theoretical concern that an US examination may cause or exacerbate the extrusion of intraocular contents. This study set out to investigate whether ocular US affects IOP. The secondary objective was to validate the intraocular pressure measurements obtained with the Diaton® as compared with standard applanation techniques (the Tono-Pen®.   Methods: We enrolled a convenience sample of healthy adult volunteers. We obtained the baseline IOP for each patient by using a transpalpebral tonometer. Ocular US was then performed on each subject using a high-frequency linear array transducer, and a second IOP was obtained during the US examination. A third IOP measurement was obtained following the completion of the US examination. To validate transpalpebral measurement, a subset of subjects also underwent traditional transcorneal applanation tonometry prior to the US examination as a baseline measurement. In a subset of 10 patients, we obtained baseline pre-ultrasound IOP measurements with the Diaton® and Tono-Pen®, and then compared them.   Results: The study included 40 subjects. IOP values during ocular US examination were slightly greater than baseline (average +1.8mmHg, p=0.01. Post-US examination IOP values were not significantly different than baseline (average -0.15mmHg, p=0.42. In a subset of 10 subjects, IOP values were not significantly different between transpalpebral and transcorneal tonometry (average +0.03mmHg, p=0.07.   Conclusion: In healthy volunteer subjects, point-of-care ocular US causes a small and transient increase in IOP. We also showed no difference between the Diaton® and Tono-Pen® methods

  19. Optical quality of toric intraocular lens implantation in cataract surgery

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    Xian-Wen Xiao

    2015-02-01

    Full Text Available AIM: To analyze the optical quality after implantation of toric intraocular lens with optical quality analysis system. METHODS: Fifty-two eyes of forty-four patients with regular corneal astigmatism of at least 1.00 D underwent implantation of AcrySof toric intraocular lens, including T3 group 19 eyes, T4 group 18 eyes, T5 group 10 eyes, T6 group 5 eyes. Main outcomes evaluated at 3mo of follow-up, included uncorrected distance visual acuity (UDVA, corrected distance visual acuity (CDVA, residual refractive cylinder and intraocular lens (IOL axis rotation. Objective optical quality were measured using optical quality analysis system (OQAS Ⅱ®, Visiometrics, Spain, included the cutoff frequency of modulation transfer function (MTFcutoff, objective scattering index (OSI, Strehl ratio, optical quality analysis system value (OV 100%, OV 20% and OV 9% [the optical quality analysis system (OQAS values at contrasts of 100%, 20%, and 9%]. RESULTS: At 3mo postoperative, the mean UDVA and CDVA was 0.18±0.11 and 0.07±0.08 logMAR; the mean residual refractive cylinder was 0.50±0.29 D; the mean toric IOL axis rotation was 3.62±1.76 degrees, the mean MTFcutoff, OSI, Strehl ratio, OV 100%, OV 20% and OV 9% were 22.862±5.584, 1.80±0.84, 0.155±0.038, 0.76±0.18, 0.77±0.19 and 0.78±0.21. The values of UDVA, CDVA, IOL axis rotation, MTFcutoff, OSI, Strehl ratio, OV100%, OV20% and OV9% depending on the power of the cylinder of the implantation were not significantly different (P>0.05, except the residual refractive cylinder (PCONCLUSION: The optical quality analysis system was useful for characterizing the optical quality of AcrySof toric IOL implantation. Implantation of an AcrySof toric IOL is an effective and safe method to correct corneal astigmatism during cataract surgery.

  20. CARACTERÍSTICA DOS SEGMENTOS SETORIAIS NO BRASIL: UMA BREVE ABORDAGEM SOBRE O SETOR DA AGROINDÚSTRIA

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    Diogo Del Fiori

    2014-07-01

    Full Text Available O presente trabalho se propõe a fazer uma análise das características setoriais do Brasil desde a segunda metade do século XIX até a data presente, com o objetivo de mostrar que embora tenham ocorrido intervenções do Estado para a realização do processo de industrialização ao longo da história brasileira, nota-se que elas foram de certa forma ineficiente, e acabaram influenciando a trajetória dos setores econômicos de tal forma que na data presente, o Brasil possui a predominância de exportação dos setores básicos, sendo uma verdadeira contradição para as metas que o Brasil almeja alcançar nas próximas décadas. Este trabalho sugere que o Brasil necessita rever suas políticas e escolher algum setor líder no mercado mundial e o setor da Agroindústria poderia ser o segmento econômico líder do país, conforme será abordado neste trabalho. Palavras-Chave: Indústrias, Estado, Setores Abstract: This work intends to make an analysis of industry characteristics in Brazil since the mid-nineteenth century to the present date in order to show that although there were state interventions to the achievement of industrialization throughout history Brazilian note that they were somewhat inefficient, and ultimately influencing the trajectory of economic sectors so that at the present time, Brazil has the predominance of the basic sectors of export, being a real contradiction to the goals that Brazil intends to reach the coming decades. This work suggests that Brazil needs to review its policies and choose a sector leader in the world market and agribusiness sector could be the key economic sector in Brazil, according to his approach in this work. Key Words: Industries, State, Sectors

  1. Nível de NT-proBNP em pacientes com síndrome coronariana aguda sem supradesnivelamento do segmento ST

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    Luiz Ricardo A. Castro

    2011-12-01

    Full Text Available FUNDAMENTO: A síndrome coronariana aguda (SCA sem supradesnivelamento do segmento ST (SCASEST está associada ao supradesnivelamento do peptídeo natriurético tipo B (BNP e aos marcadores de necrose miocárdica, embora se desconheça a correlação dessa síndrome ao escore de trombólise no infarto do miocárdio (TIMI e à função ventricular esquerda. OBJETIVO: Avaliar a correlação entre os níveis do fragmento N-terminal do peptídeo natriurético tipo B (NT-proBNP e os marcadores de necrose miocárdica (creatinofosfoquinase fração músculo-cérebro CK-MB e troponina I, bem como entre o escore de risco TIMI e a fração de ejeção do ventrículo esquerdo (FEVE nos pacientes com síndrome coronariana aguda sem supradesnivelamento do segmento ST. MÉTODOS: Oitenta e sete pacientes com síndrome coronariana aguda sem supradesnivelamento do segmento ST foram divididos em dois grupos: 37 (42,5% com angina instável e 50 (57,5% com infarto agudo do miocárdio sem supradesnivelamento do segmento ST (IAMSSST. RESULTADOS: A fração de ejeção do ventrículo esquerdo superior a 40% foi encontrada em 86,2% do total da amostra. Os níveis séricos de NT-proBNP foram maiores em pacientes com infarto do miocárdio sem supradesnivelamento do segmento ST, em comparação àqueles com angina instável (p<0,001. O aumento dos níveis de NT-proBNP foi associado ao aumento de troponina I (rs=0,425, p<0,001, pico de CK-MB (rs=0,458, p<0,001 e FEVE (rs=-0,345, p=0,002, não havendo correlação com o escore de risco TIMI (rs=0,082, p=0,44. Na análise multivariada, a fração de ejeção do ventrículo esquerdo e a troponina I correlacionaram-se de forma independente aos níveis de NT-proBNP (p=0,017 e p=0,002, respectivamente. CONCLUSÃO: O aumento dos níveis de NT-proBNP em pacientes com síndrome coronariana aguda sem supradesnivelamento do segmento ST não está relacionado exclusivamente à redução da fração de ejeção do ventrículo esquerdo

  2. Sistema de garantías: financiamiento a las PyMEs a través del mercado de capitales en Argentina. Instrumento: cheque de pago diferido

    OpenAIRE

    Gonzalez Barros, Ariel

    2014-01-01

    Este trabajo propone realizar un análisis exhaustivo sobre uno de los nuevos instrumentos disponibles para brindar financiamiento a las PyMEs en la Argentina a través del Mercado de Capitales. Específicamente se abordará el estudio del financiamiento a dicho segmento a través de la negociación del cheque de pago diferido, instrumento derivado de la obtención de avales por parte de las Sociedades de Garantía Reciproca. Se detallará la evolución del marco normativo vigente, tendiente a operativ...

  3. Ocular Onchocerciasis in the Yanomami Communities from Brazilian Amazon: Effects on Intraocular Pressure

    Science.gov (United States)

    Herzog-Neto, Guilherme; Jaegger, Karen; do Nascimento, Erika S.; Marchon-Silva, Verônica; Banic, Dalma M.; Maia-Herzog, Marilza

    2014-01-01

    To determine the influence of onchocercal eye disease on the intraocular pressure of the Yanomami Tribe Aratha-ú of Roraima State, Brazil, considered endemic for onchocerciasis, a total of 86 patients were submitted to an ophthalmologic exam that included external examination, slit lamp examination, intraocular pressure measurement, and a fundus ophthalmoscope examination. A high prevalence of onchocerciasis-related eye lesions was encountered in 68.6% of the patients. Punctate keratitis and microfilariae in the anterior chamber were found in ∼28%. The mean of intraocular eye pressure found was 10.47 mm of Hg. PMID:24297812

  4. MARKETING DE RELACIONAMENTO E FIDELIZAÇÃO: UMA ABORDAGEM NO SEGMENTO “CLIENTE ESTILO” EM UMA AGÊNCIA BANCÁRIA

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    Adriano Moreira dos Santos

    2011-08-01

    Full Text Available Este trabalho tem como tema o Marketing de Relacionamento, que diz respeito à fidelização de clientes, consequência de um processo de segmentação com ênfase no atendimento. Objetiva estudar e analisar o atendimento diferenciado aos clientes do Segmento Estilo, pessoa física, da Agência X, do Banco do Brasil, identificando e comentando os possíveis atributos que influenciam na satisfação e, por sua vez, na fidelização desses clientes. Desenvolve-se este estudo através de levantamento bibliográfico e documental, bem como por meio de uma pesquisa do tipo descritiva, a partir de estudo de caso em uma agência bancária, onde são pesquisados vários atributos em relação ao atendimento, aos serviços prestados pelo banco, ao relacionamento do banco com o cliente, questões que interferem na fidelização e na satisfação dos clientes do segmento estudado. Ao final deste estudo, confirmou-se que vários aspectos devem ser considerados no atendimento diferenciado aos clientes do segmento pesquisado, a fim de satisfazê-los e fideliza-los. Dentre esses aspectos, destacam-se: a eficiência e agilidade no atendimento, indo ao encontro das necessidades dos clientes; a capacidade de soluções de problemas; o bom relacionamento entre cliente e banco; o atendimento segmentado fortalece a relação de parceria entre banco e cliente. Palavras-chave: Marketing. Relacionamento. Fidelização. Cliente Estilo. Agência Bancária.

  5. Anatomía funcional del raquis y la influencia de la cintura pelviana y los músculos participantes

    OpenAIRE

    Ruager, Gerardo Andrés

    2013-01-01

    El objetivo de la siguiente ponencia es la de revalorizar el estudio anatómico y funcional del ráquis humano desde una perspectiva funcional, desde lo estático y lo dinámico, y no sólo desde lo cadavérico y horizontal. Se dará una revisión de la constitución de la columna vertebral, de la cintura pelviana y la cintura escapular, los músculos participantes y del aparato ligamentario. Se explicaran los tipos y rangos de movimientos del ráquis en su conjunto y de los segmentos que lo const...

  6. Intraocular surgery in a large diabetes patient population

    DEFF Research Database (Denmark)

    Ostri, Christoffer

    2014-01-01

    The prevalence of diabetes is on the increase in developed countries. Accordingly, the prevention and treatment of vision-threatening diabetic eye complications is assuming greater importance. The overall aim of this thesis is to analyse risk factors for intraocular surgery in a large diabetes...... population and to report surgical results. The specific objectives are to (1) estimate the incidence of diabetic vitrectomy and analyse risk factors (Study I), (2) report long-term results, prognostic factors and incidence of cataract surgery after diabetic vitrectomy (Study II), (3) report results...... and prognostic factors after cataract surgery in diabetes patients (Study III) and (4) analyse risk factors for diabetic papillopathy with emphasis on metabolic control variability (Study IV). All studies are based on a close-to-complete national surgery register and a large, closely followed diabetic...

  7. Laboratory analyses of two explanted hydrophobic acrylic intraocular lenses

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    Yunhai Dai

    2014-01-01

    Full Text Available Two three-piece hydrophobic acrylic intraocular lenses (IOLs were explanted from two patients at 7 and 9 years, respectively, after implantation, because of poor fundus visualisation and/or a clinically significant decrease in visual acuity related to their opacified IOLs. In addition to light microscopy, scanning electron microscopy and energy dispersive X-ray spectroscopy, confocal laser scanning microscopy was used for the first time to observe the explanted IOLs. The clinical aspect seemed to correspond to the phenomenon of surface light scattering, while laboratory analyses showed dense glistenings in the central layer of the IOL optic, which had no change next to the surface. Further studies on these phenomena are needed.

  8. Scleral fixation of a single-piece multifocal intraocular lens.

    Science.gov (United States)

    Can, Ertugrul; Basaran, M Resat; Gül, Adem

    2013-01-01

    We describe an ab interno technique for injector implantation of a one-piece multifocal intraocular lens (IOL). Transscleral fixation of multifocal posterior chamber IOL implantation using an injector with ab interno technique was performed in an eye of a 9-year-old girl who had undergone pars plana lensectomy 2 years before for bilateral lens subluxation with unknown etiology. No major complications were encountered during a 3-month follow-up of the patient and excellent centration was observed during the follow-up period. Her preoperative best spectacle-corrected distance visual acuity of 20/32 improved to uncorrected distance visual acuity of 20/25. Closed-loop design of IOL served the function of eyelets and position of the IOL was provided using only a 2-point fixation. Intraoperative position adjustment of the IOL provided an excellent centralization of multifocal IOL.

  9. Bilateral intraocular lens subluxation secondary to haptic angulation.

    Science.gov (United States)

    Moreno-Montañés, Javier; Fernández-Hortelano, Ana; Caire, Josemaría

    2008-04-01

    An 82-year-old man had uneventful phacoemulsification with bilateral implantation of a hydrophilic acrylic, single-piece intraocular lens (IOL) (ACR6D SE, Laboratoires Cornéal). Five years later, simultaneous and bilateral IOL subluxations occurred. In both eyes, the subluxation was situated on the side of one haptic that had moved forward (temporal area in the right eye and superior area in the left eye). In the right eye, the haptic-capsular bag was entrapped by the pupil and produced endothelial damage. A transscleral suture was placed over and under the subluxated haptic through the anterior and posterior capsules to capture the haptic. The haptic was then sutured to the sclera. No postoperative complications developed. We hypothesize that 10-degree angulated and broad haptic junctions can lead to zonular damage and IOL subluxation.

  10. Scleral fixation of one piece intraocular lens by injector implantation.

    Science.gov (United States)

    Can, Ertugrul; Basaran, Resat; Gul, Adem; Birinci, Hakki

    2014-08-01

    With an ab-interno technique of transscleral suturing of current one-piece posterior chamber intraocular lenses (PC IOLs) by injector implantation in the absence of capsular support, we aimed to demonstrate the possibility of the implantation of one-piece acrylic PC IOLs that might be produced in the future for only scleral fixation through small clear corneal incision. Case report and literature review. This procedure has been performed in eight aphakic eyes with four different types of IOLs. Good centration was achieved with minimal technical effort. All patients had well-centered and stable lenses postoperatively during 9-18 months follow-up. We managed to decrease the risks of surgical trauma and intricate surgical maneuvers requirement. With this technique, excessive fluid leakage and consecutive hypotony can be minimized.

  11. Ectopic intraocular lens: An unusual complication of cataract surgery

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    Mehul A Shah

    2014-01-01

    Full Text Available We wish to report an unusual complication of intraocular lens (IOL insertion following uneventful phacoemulsification. After successful phacoemulsification surgery, a hydrophobic acrylic IOL was loaded in the injector for insertion into the capsular bag. During insertion, the IOL inadvertently extended into the corneal stromal lamella. The complication was recognized at a late stage, and the foldable acrylic lens was retrieved and reinserted correctly in the bag. The anterior chamber was made viscoelastically taut and was maintained in this state for 10 min, followed by a routine viscoelastic wash and air bubble injection. Cornea was slightly edematous with stromal haze, and the corneal thickness was 908 μm. At the 1-month follow-up visit, the patient′s vision was 20/40, the stromal haze had subsided, the corneal thickness was 572 μm, and the patient was comfortable. Though it was unknown complication, following proper management patient recovered satisfactorily.

  12. Aplicação de princípios gestálticos no planejamento de estruturas composicionais utilizadas na peça segmentos

    OpenAIRE

    Oliveira, Helder Alves de

    2014-01-01

    Este trabalho examina o potencial da aplicação dos princípios da Psicologia da Gestalt no planejamento de estruturas composicionais na obra Segmentos, para orquestra sinfônica. As análises gestálticas de obras musicais realizadas por diversos autores, como Meyer (1956), Lerdahl e Jackendoff (1983), e Tenney e Polansky (1980), foram utilizadas neste trabalho sob um viés prescritivo. As analogias entre os gestos musicais e as características da percepção de objetos visuais, segun...

  13. Turismo de bem-estar: análise dos serviços do segmento em spas day – Natal/RN, Brasil

    OpenAIRE

    Islaine Cristiane Oliveira Gonçalves da Silva; Leilianne Michelle Trindade da Silva Barreto; Lissa Valéria Fernandes Ferreira

    2016-01-01

    O turismo de bem-estar tem apresentado crescimento significativo nas últimas décadas. Subproduto do turismo de saúde, o então chamado “wellness” do turismo tem alcançado um público com melhores poderes aquisitivos, nos quais buscam sair da rotina em um momento de relaxamento do corpo e da mente. O objetivo principal da pesquisa foi de analisar o processo de gestão estratégica da qualidade dos serviços do segmento de turismo de bem-estar em Spas day de Natal/RN, Brasil. A pesquisa teve como me...

  14. Competitividad de Cartagena como destino del turismo de congresos

    OpenAIRE

    Pérez Merlos, Laura

    2011-01-01

    Este trabajo lleva a cabo un análisis de la posición competitiva de la ciudad de Cartagena como destino del turismo de reuniones y congresos. Para ello se estudian la situación y principales tendencias seguidas por el turismo de reuniones y congresos en la actualidad y qué factores son los determinantes básicos de la competitividad de un destino en este contexto. Finalmente se formulan recomendaciones orientadas a facilitar un mejor posicionamiento de Cartagena en este segmento de...

  15. Una palma nueva del género Desmoncus

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    Dugand Armando

    1943-04-01

    Full Text Available Según el colector, el nombre vulgar de esta palma es matamba. Otra especie de Desmoncus, conocida también vulgarmente con el nombre de matamba, se encuentra en el Bajo Magdalena y la región litoral caribe de Colombia; es D. horridus Splitg. ex Mart., que se distingue de D. myriacanthos por tener los segmentos foliáceos mucho más anchos, casi elípticos, el raquis de las frondas menos aguijoneado y los aguijones más largos. De D. horridus he examinado Dugand. & García-Barriga 2506, Depto. del Magdalena, Rio Ariguani.

  16. Design of a Test Bench for Intraocular Lens Optical Characterization

    Energy Technology Data Exchange (ETDEWEB)

    Alba-Bueno, Francisco; Vega, Fidel; Millan, Maria S, E-mail: francisco.alba-bueno@upc.edu, E-mail: fvega@oo.upc.edu, E-mail: millan@oo.upc.edu [Departamento de Optica y Optometria, Universidad Politecnica de Cataluna, C/ Violinista Vellsola 37, 08222 Terrassa (Spain)

    2011-01-01

    The crystalline lens is the responsible for focusing at different distances (accommodation) in the human eye. This organ grows throughout life increasing in size and rigidity. Moreover, due this growth it loses transparency through life, and becomes gradually opacified causing what is known as cataracts. Cataract is the most common cause of visual loss in the world. At present, this visual loss is recoverable by surgery in which the opacified lens is destroyed (phacoemulsification) and replaced by the implantation of an intraocular lens (IOL). If the IOL implanted is mono-focal the patient loses its natural capacity of accommodation, and as a consequence they would depend on an external optic correction to focus at different distances. In order to avoid this dependency, multifocal IOLs designs have been developed. The multi-focality can be achieved by using either, a refractive surface with different radii of curvature (refractive IOLs) or incorporating a diffractive surface (diffractive IOLs). To analyze the optical quality of IOLs it is necessary to test them in an optical bench that agrees with the ISO119679-2 1999 standard (Ophthalmic implants. Intraocular lenses. Part 2. Optical Properties and Test Methods). In addition to analyze the IOLs according to the ISO standard, we have designed an optical bench that allows us to simulate the conditions of a real human eye. To do that, we will use artificial corneas with different amounts of optical aberrations and several illumination sources with different spectral distributions. Moreover, the design of the test bench includes the possibility of testing the IOLs under off-axis conditions as well as in the presence of decentration and/or tilt. Finally, the optical imaging quality of the IOLs is assessed by using common metrics like the Modulation Transfer Function (MTF), the Point Spread Function (PSF) and/or the Strehl ratio (SR), or via registration of the IOL's wavefront with a Hartmann-Shack sensor and its

  17. Primary intraocular lens implantation for penetrating lens trauma in Africa.

    Science.gov (United States)

    Bowman, R J; Yorston, D; Wood, M; Gilbert, C; Foster, A

    1998-09-01

    This study aimed to audit the surgical strategy of primary posterior chamber intraocular lens implantation for cases of recent penetrating trauma involving the lens in an African population. Retrospective, noncomparative case series. Seventy-two cases are reported, including all patients who underwent primary intraocular lens implantation for traumatic cataract extraction performed within 1 month of injury between 1988 and 1996. Demographic characteristics and follow-up attendance rates are analyzed. Surgical technique and the occurrence of intraoperative and postoperative complications are reported. Visual outcomes are reported with detailed analysis for cases of poor visual outcome. Mean age was 14.3 years (standard deviation = 11.1), 57 (79%) were male and 15 (21%) were female (chi-square = 23.66, P capsule had been breached by the trauma in 27 (38%) cases, and 15 of these required anterior vitrectomy. Capsular fixation of the implant was achieved in 49% of patients, the remainder having sulcus fixation. Intraoperative rupture of the posterior capsule occurred in four cases. The only common postoperative complication was acute fibrinous anterior uveitis, which occurred in 29 (40%) patients, and 32% of patients followed up for at least 6 months required secondary posterior capsulotomy. This was more common in younger patients (chi-square = 4.2, P < 0.05). Corrected postoperative visual acuities were available for 51 patients, of which 71% achieved 20/60 or better visual acuity. Patients 6 years of age or younger were less likely to achieve 20/60 (chi-square = 6.61, P = 0.01). This surgical strategy has proved successful, producing good visual results and causing no sight-threatening complications. Primary posterior capsulotomy may be appropriate for younger patients.

  18. Analysis of phakic before intraocular lens implantation for fundus examination

    Directory of Open Access Journals (Sweden)

    Juan Chen

    2014-10-01

    Full Text Available AIM:To investigate the findings of the eyes which were examined preoperatively by three mirror contact lens before the implantation of implantable collamer lens(ICL. To analysis the retinal pathological changes and to explore the clinical analysis of early diagnosis and treatment in retinopathy on fundus examination before operation. METHODS:The retrospective case series study included 127 eyes of 64 patients who underwent phakic intraocular lens implantation were received the fundus examination by three mirror from April 2011 to April 2012 in our hospital. The age, refractive diopter, the findings of Goldmann three mirror examination and the condition of retinal photocoagulation were analysed and concluded.RESULTS: A total of 34 eyes(26.8%out of all 127 eyes(64 caseswere found to have peripheral retinal pathological changes. Eight eyes(6.3%with retinal holes, 15 eyes(11.8%with retinal lattice degeneration, 5 eyes(3.9%with retina cream degeneration, 3 eyes(2.4%with retinal paving stone degeneration,2 eyes with vitreoretinal adhesion and traction,1 eye(0.8%with retinal hemorrhage. Twenty-five cases were given retinal photocoagulation and then received the ICL implantation after 3mo. The follow-up time was 1a. No retinal detachment happened.CONCLUSION:Phakic before intraocular lens implantation for fundus examination by three mirror is contributed to find the peripheral retinal pathological changes and abnormity. And make the appropriate treatment before operation for improving the security of operation, it can also give help to the postoperative follow-up of the fundus of these patients.

  19. Intraocular penetration of sequentially instilled topical moxifloxacin, gatifloxacin, and levofloxacin

    Directory of Open Access Journals (Sweden)

    Koji Sugioka

    2009-10-01

    Full Text Available Koji Sugioka1, Masahiko Fukuda1, Shohei Komoto1, Motoki Itahashi1, Masakazu Yamada2, Yoshikazu Shimomura11Department of Ophthalmology, Kinki University School of Medicine, Osaka-Sayama City, Osaka, Japan; 2Division for Vision Research, National Institute of Sensory Organs, National Tokyo Medical Center, Tokyo, JapanPurpose: The objective of the study was to compare the intraocular penetration levels of the newer fluoroquinolones, moxifloxacin, gatifloxacin, and levofloxacin in the rabbit’s cornea, aqueous humor, and conjunctiva after topical instillation.Methods: 0.5% moxifloxacin, 0.3% gatifloxacin, and 0.5% levofloxacin were instilled in random sequence in both eyes of nine New Zealand White rabbits at two-minute intervals. Instillation was repeated every 15 minutes for a total of three drops of each fluoroquinolone per eye. Three additional animals had only moxifloxacin instilled bilaterally using the same schedule. Sixty minutes after the final instillation, the rabbits were sacrificed for determination of corneal, aqueous humor, and conjunctival fluoroquinolone concentrations using highperformance liquid chromatography.Results: Moxifloxacin achieved significantly higher concentrations than levofloxacin and gatifloxacin in the cornea (P = 0.0102 and P = 0.0006, respectively, aqueous humor (P = 0.0015 and P < 0.0001, respectively, and conjunctiva (P = 0.0191 and P = 0.0236, respectively. Conclusions: 0.5% moxifloxacin eyedrops provided superior intraocular penetration in rabbits’ eyes compared with the two other fluoroquinolones, 0.5% levofloxacin and 0.3% gatifloxacin.Keywords: fluoroquinolone, gatifloxacin, levofloxacin, moxifloxacin, penetration, rabbit

  20. Intracorneal and Intraocular Invasion of Ocular Surface Squamous Neoplasia after Intraocular Surgery: Report of Two Cases and Review of the Literature.

    Science.gov (United States)

    Murillo, Juan C; Galor, Anat; Wu, Michael C; Kye, Natasha K; Wong, James; Ahmed, Ibrahim O; Joag, Madhura; Shalabi, Nabeel; Lahners, William; Dubovy, Sander; Karp, Carol L

    2017-01-01

    The aim of this paper was to describe 2 cases of ocular surface squamous neoplasia (OSSN) of the conjunctiva with intracorneal and intraocular extension following intraocular surgery. We conducted a clinical pathological retrospective case series. Case 1 underwent cataract surgery in the setting of an unnoticed adjacent OSSN. An excisional biopsy with cryotherapy and intraoperative mitomycin C was subsequently performed, confirming OSSN. The patient had two recurrences treated topically with resolution. While the conjunctiva remained clear, a corneal haze emanating from the cataract incision site was noted. Penetrating keratoplasty (PK) for this haze revealed midstromal infiltrative carcinoma. Case 2 had a history of herpes simplex keratitis that ultimately required corneal grafts. Fifteen years later, he developed an OSSN treated with excisional biopsy and had clear margins. Eight months later, he presented with a recurrence of his OSSN and was treated briefly with topical interferon for 4 weeks; however, he developed an infectious keratitis with a corneal perforation requiring another PK. Four months after PK, low-grade inflammation was noted. Cytology of the anterior chamber aspirate revealed neoplastic squamous cells. Another PK was then performed. Pathology confirmed extensive intraocular neoplasia. Limited exenteration was performed. Patients with a history of OSSN may be at increased risk of neoplastic intraocular extension following intraocular surgery.

  1. Opacificação tardia de lente intra-ocular de polimetilmetacrilato (PMMA: relato de caso Late opacification of a polymethylmethacrylate (PMMA intraocular lens: case report

    Directory of Open Access Journals (Sweden)

    Otacílio de Oliveira Maia Júnior

    2005-10-01

    Full Text Available O implante das lentes intra-oculares foi grande avanço na reabilitação visual de pacientes submetidos à cirurgia de extração da catarata. Contudo, os materiais utilizados na fabricação destas lentes, apesar de terem boa biocompatibilidade, são passíveis de alterações posteriores ao implante. No presente estudo, os autores relatam um caso raro de opacificação tardia de lente de polimetilmetacrilato, material inerte e bem tolerado intra-ocularmente, discutindo aspectos importantes no manejo desta complicação, bem como indicação de explante e substituição da lente.The use of intraocular lenses was a great advance in visual recovery after cataract surgery. Although usually with good biocompatibility, some alterations in the intraocular lens material may occur after implantation. Polymethylmethacrylate was the first intraocular lens material to be used on a large scale and assumed to be inert and well-tolerated. We present a rare case of late opacification of a polymethylmethacrylate lens, discussing important aspects of its management such as the indication for intraocular lens exchange.

  2. SECUENCIACIÓN DEL GENOMA COMPLETO DEL Potato yellow vein virus (PYVV) EN TOMATE ( Solanum lycopersicum ) EN COLOMBIA

    OpenAIRE

    Laura MUÑOZ BAENA; Pablo Andrés GUTIÉRREZ SÁNCHEZ; Mauricio MARÍN MONTOYA

    2017-01-01

    Potato yellow vein virus (PYVV), es uno de los fitopatógenos más limitantes para la producción de papa en la región de Los Andes. A pesar que se le ha detectado infectando tomate en Colombia, el conocimiento de las características biológicas de las cepas presentes en este hospedante es muy limitado. En este estudio, utilizando secuenciación masiva de nueva generación (NGS), se obtuvo la secuencia completa de los tres segmentos genómicos del PYVV en plantas de tomate en M...

  3. Nuevo esteroide tópico en el tratamiento del edema macular

    Directory of Open Access Journals (Sweden)

    Ceija Molina Cisneros

    Full Text Available El pilar principal de tratamiento de las inflamaciones oculares tanto postquirúrgicas como endógenas, se basa en el uso de esteroides. Aunque estos medicamentos son efectivos, su empleo no está exento de riesgos como la hipertensión ocular y la aceleración de la formación de la catarata, principalmente en el caso de los esteroides más fuertes como la prednisolona y la betametasona. Esta revisión estuvo encaminada a la profundización del conocimiento sobre la bioquímica y el desarrollo del difluprednate, nueva droga esteroidea sintética de alta potencia, cuyo uso está aprobado por la Food and Drug Administration (FDA para el tratamiento del edema macular después de la cirugía del segmento anterior. Se analizaron algunos aspectos de este medicamento off-label como la farmacocinética, el metabolismo, la distribución ocular del medicamento y utilidad en las fases I, II y III de ensayos clínicos sobre su utilización en pacientes con inflamaciones posoperatorias, tanto del segmento anterior como posterior y con uveítis anterior.

  4. Autorefraction versus subjective refraction in a radially asymmetric multifocal intraocular lens

    NARCIS (Netherlands)

    van der Linden, Jan Willem; Vrijman, Violette; Al-Saady, Rana; El-Saady, Rana; van der Meulen, Ivanka J.; Mourits, Maarten P.; Lapid-Gortzak, Ruth

    2014-01-01

    To evaluate whether the automated refraction (AR) correlates with subjective manifest (MR) refraction in eyes implanted with radially asymmetric multifocal intraocular lens (IOLs). This retrospective study evaluated 52 eyes (52 patients) implanted with a radially asymmetric multifocal IOL (LS-312

  5. Intraocular pressure measurement with the Tono-Pen through soft contact lenses.

    Science.gov (United States)

    Panek, W C; Boothe, W A; Lee, D A; Zemplenyi, E; Pettit, T H

    1990-01-15

    We evaluated a miniaturized digital and electronic tonometer, the Tono-Pen, for accuracy of intraocular pressure measurement in the presence of a contact lens. In the manometric study, the Tono-Pen was used to measure a known intraocular pressure, ranging from 10 mm Hg to 60 mm Hg in a cadaver eye over soft contact lenses with different powers and a plano-T bandage lens. There was significant bias in pressure measurement over all contact lenses except for the plano-T, which had no bias at any level. In the clinical study, the intraocular pressures of 40 eyes in 20 normal patients were measured with and without a plano-T contact lens in place. Analysis of variance showed no significant interactive effect between the right and left eyes, with or without the lens. There was no significant difference in the Tono-Pen measurement of intraocular pressure over a plano-T contact lens compared with no lens.

  6. Posterior Segment Intraocular Foreign Body: Extraction Surgical Techniques, Timing, and Indications for Vitrectomy

    Directory of Open Access Journals (Sweden)

    Dante A. Guevara-Villarreal

    2016-01-01

    Full Text Available Ocular penetrating injury with Intraocular Foreign Body (IOFB is a common form of ocular injury. Several techniques to remove IOFB have been reported by different authors. The aim of this publication is to review different timing and surgical techniques related to the extraction of IOFB. Material and Methods. A PubMed search on “Extraction of Intraocular Foreign Body,” “Timing for Surgery Intraocular Foreign Body,” and “Surgical Technique Intraocular Foreign Body” was made. Results. Potential advantages of immediate and delayed IOFB removal have been reported with different results. Several techniques to remove IOFB have been reported by different authors with good results. Conclusion. The most important factor at the time to perform IOFB extraction is the experience of the surgeon.

  7. Geología del este de Costa Rica y el norte de Panamá

    OpenAIRE

    Escalante, Gregorio; Astorga, Allana

    2011-01-01

    Costa Rica y Panamá forman parte del Bloque Chorotega, el cual conforma una provincia geológica de basamento oceánico, de edad Mesozoica - Conozoica que representa un arco de islas intraoceánico maduro, que ha evolucionado desde el Cretácico Superior. El segmento formado por el este de Costa Rica y el norte de Panamá constituye una unidad tectónica limitada por fallas, donde el límite norte corresponde con el Cinturón Deformado del Norte de Panamá, que en la latitud de Puerto Limón, se transf...

  8. A case of Alagille syndrome complicated by intraocular lens subluxation and rhegmatogenous retinal detachment

    OpenAIRE

    Fukumoto, Masanori; Ikeda,Tsunehiko; Sugiyama,Tetsuya; Ueki,Mari; Isizaki,Eisuke; Satou,Takaki

    2013-01-01

    Masanori Fukumoto, Tsunehiko Ikeda, Tetsuya Sugiyama, Mari Ueki, Takaki Sato, Eisuke Ishizaki Department of Ophthalmology, Osaka Medical College, Takatsuki City, Japan Abstract: This case report describes a case of Alagille syndrome with developing intraocular lens subluxation and rhegmatogenous retinal detachment 4 years after cataract surgery. A 15-year-old female patient with Alagille syndrome-associated cataracts in both eyes underwent phacoemulsification aspiration and intraocular lens ...

  9. [The progress of studies on intraocular lens implantation in cataract with high myopia].

    Science.gov (United States)

    Liu, Xue; Wan, Xiuhua

    2015-07-01

    With development of the technology of cataract surgery, combined phacoemulsification and intraocular lens implantation in cataract with high myopia has been widely carried out in clinical treatment. Due to the particularity of high myopia, phacoemulsification in patients with cataract and high myopia is difficult and has recently received a lot of attentions. In this paper, preoperative examinations, the selection of intraocular lenses, surgery methods and surgical complications of cataract surgery in patients with cataract and high myopia are briefly reviewed.

  10. MRt in the recurrent retinal detachment diagnosis after intraocular tamponade media injection: state of the art

    International Nuclear Information System (INIS)

    Manfre, L.; Midiri, M.; Casto, A.; Angileri, T.; Cardinale, A.

    1994-01-01

    Inraocular Silicon (SO), Fluorosilicon (FSO) oil or Perfluorocarbon fluid (PFCL) injection is a new succesfull surgical technique in the treatment detachment. After personal casu istic review, we report our experience in 37 patients, who underwent pars plana vitrectomy with intraocular SO, FSO or PFCL in injection for retinal detachment, monitored with Magnetic Resonance Imaging controls. MRI, showing no significant oil-related artifcats, revealed as a confident, non-invasive imaging modality in evaluating patient undergone tamponade media intraocular injection

  11. Cambios de la presión intraocular en pacientes con hipertensión arterial

    Directory of Open Access Journals (Sweden)

    G. Tenorio-Guajardo

    2014-07-01

    Conclusiones: En este estudio se encontró correlación entre presión intraocular y la presión arterial diastólica, pero no se encontró correlación entre la sistólica. Es recomendable vigilar la presión intraocular en pacientes hipertensos, especialmente en aquellos con hipertensión diastólica persistente y con antecedentes familiares de glaucoma.

  12. Evaluación imaginológica del intestino delgado por TC y RM

    Directory of Open Access Journals (Sweden)

    Dr. S. Andres O´Brien

    2013-01-01

    Full Text Available El intestino delgado es el segmento más difícil de evaluar del tubo digestivo. Con el desarrollo tecnológico, nuevas modalidades de imagen como la Enteroclisis por Tomografía Computada y por Resonancia Magnética han permitido un mejor rendimiento y resolución en la evaluación de patologías intestinales como enfermedad de Crohn, tumores de intestino delgado, estudio de hemorragia digestiva y obstrucción intestinal parcial, entre otras. En el presente artículo se presenta una revisión de las indicaciones, aspectos técnicos y una revisión pictográfica de las principales patologías que afectan este segmento.

  13. Turismo de bem-estar: análise dos serviços do segmento em spas day – Natal/RN, Brasil

    Directory of Open Access Journals (Sweden)

    Islaine Cristiane Oliveira Gonçalves da Silva

    2016-01-01

    Full Text Available O turismo de bem-estar tem apresentado crescimento significativo nas últimas décadas. Subproduto do turismo de saúde, o então chamado “wellness” do turismo tem alcançado um público com melhores poderes aquisitivos, nos quais buscam sair da rotina em um momento de relaxamento do corpo e da mente. O objetivo principal da pesquisa foi de analisar o processo de gestão estratégica da qualidade dos serviços do segmento de turismo de bem-estar em Spas day de Natal/RN, Brasil. A pesquisa teve como metodologia a observativa participante, fazendo a utilização de ckeck-list dos serviços baseado no modelo SERVPERF. Estudo qualitativo, transversal, intencional, não-probabilístico. Como resultados pode-se analisar que há frequência de turistas neste segmento e ainda que as estratégias de gestão devem se embasar mais na satisfação dos clientes, quanto a sua total atenção ao paciente, já que este carece de liberações de tensões e necessita do mínimo de contrangimento e/ou estresse.

  14. Intraocular pressure variations during zygomatic fracture reduction and fixation: a clinical study.

    LENUS (Irish Health Repository)

    Murray, Dylan J

    2012-02-03

    BACKGROUND: The reduction of midface fractures has been associated with the rare but devastating complication of blindness. An increase in intraocular pressure is important in the mechanism of blindness in this setting. In this study, the authors assessed the intraocular pressure in patients who underwent zygomatic fracture reduction (with or without fixation). METHODS: Using applanation tonometry, 29 patients underwent intraocular pressure measurements before, during, and after fracture fixation. The contralateral pressures were measured and used as the control. RESULTS: There were 29 patients with a mean age of 35 years, and the mean time to surgery was 5 days. Preoperatively, all patients had normal intraocular pressures and normal visual acuity. All patients underwent a Gillies lift and 18 patients required open reduction and fixation of the frontozygomatic suture (n = 4) or the infraorbital margin (n = 2), and the remainder (n = 12) required fixation of both points. There was no statistically significant increase in the intraocular pressures following the reduction of uncomplicated zygomatic fractures. Statistically significant pressure reductions were noted immediately after reduction and fixation. CONCLUSIONS: The surgical reduction of uncomplicated zygomatic fractures has no adverse effect on the intraocular pressure. It is the authors\\' opinion that adjunctive measures to reduce the pressures are unnecessary.

  15. Pigment dispersion syndrome associated with intraocular lens implantation: a new surgical technique

    Directory of Open Access Journals (Sweden)

    M Isabel Canut Jordana

    2010-11-01

    Full Text Available M Isabel Canut Jordana1, Daniel Pérez Formigó1, Rodrigo Abreu González2, Jeroni Nadal Reus11Barraquer Ophthalmology Centre, Barcelona, Spain; 2University Hospital of La Candelaria, Tenerife, SpainAims: We report the case of a myopic patient who, after intraocular lens transplant in the posterior chamber, suffered elevated intraocular pressure due to pigment dispersion, with recurrent episodes of blurred vision. The patient was treated with a new surgical technique that can avoid potential iridolenticular contact.Methods: Complete ophthalmologic examination and optical coherence tomography (OCT of the anterior segment were performed.Results: Contact between the pigmentary epithelium and the iris with an intraocular lens was revealed by utrasound biomicroscopy and OCT. In this case, Nd:YAG laser iridotomy and laser iridoplasty were not effective for iridolenticular separation and control of the pigment dispersion. We propose a new technique: stitches on the surface of the iris to obtain good iridolenticular separation and good intraocular pressure control.Conclusion: Stitches on the iris surface should be considered as optional therapy in pigmentary glaucoma secondary to intraocular lens implantation. This surgical technique can avoid potential iridolenticular contacts more definitively.Keywords: pigmentary glaucoma, intraocular lens, optical coherence tomography, laser

  16. Results and complications of scleral fixated (Sutured posterior chamber intraocular lens implantation

    Directory of Open Access Journals (Sweden)

    Amoozadeh J

    2001-08-01

    Full Text Available Optical rehabilitation of the patient with aphakia who cannot tolerate contact lenses present a therapeutic challenge. In the absence of capsular support, anterior chamber lenses have been widely used. On the other hand intraocular lens implantation of scleral sutured posterior chamber intraocular lens during penterating keratoplasty or insufficient iris support is recommended. The purpose of this study is to evaluate the clinical outcome and complication in 17 patients who underwent scleral-fixation of an intraocular lens.We studied prospectively the results of posterior chamber intraocular lens implantation by scleral fixation in 17 eyes of 17 patients without a complete posterior lens capsule support at farabi Eye Hospital. Uncorrected visual acuity improved from counting finger to 20/40 or better in 9 eyes (53 percent. The following complications were observed during the mean postoperative follow-up of 7.2 (range 3-12 months; increased intraocular pressure in 5 eyes, vitreous hemorrhage and icr hyphema in 2 eyes, cystoid macular edema (CME and vitritis in one eye, and endophthalmitis and retinal detachment in one eye. Posterior chamber intraocular lens implantation by scleral fixation is a relatively safe procedure and can be recommended for many patients

  17. Topical tissue plasminogen activator appears ineffective for the clearance of intraocular fibrin.

    Science.gov (United States)

    Zwaan, J; Latimer, W B

    1998-06-01

    To determine the efficacy of topical tissue plasminogen activator (tPA) for the resolution of postoperative or inflammatory intraocular fibrinous exudates. Each treatment consisted of drops of 1 mg/ml tPA given 9 times 5 minutes apart. Records were reviewed and the results at 24 and 48 hours were recorded. Sixty-two patients had a total of 94 treatments. Fibrin exudates following intraocular surgery in 34 patients were treated 44 times. In 6 patients there was a positive result. Fibrin associated with intraocular infection was treated in 9 patients. None showed clear improvement. Nineteen patients had a total of 34 treatments for poorly controlled intraocular pressure (IOP) after glaucoma surgery. Five patients showed adequate control of the IOP, 12 did not change, and 2 had a questionable improvement. Eleven patients had adequate IOP control after additional treatment. Seven required suture lysis, 2 ab interno bleb revision, and 2 YAG capsulotomy or iridotomy to reduce the IOP to an acceptable level. Within the limits of this retrospective study and taking into account that fibrin may resolve spontaneously, it appears that topical tPA drops are not effective for the liquefaction of intraocular fibrin after surgery or in association with intraocular inflammation. They did not improve IOP control after glaucoma surgery.

  18. EX VIVO MODEL FOR THE CHARACTERIZATION AND IDENTIFICATION OF DRYWALL INTRAOCULAR FOREIGN BODIES ON COMPUTED TOMOGRAPHY.

    Science.gov (United States)

    Syed, Reema; Kim, Sung-Hye; Palacio, Agustina; Nunery, William R; Schaal, Shlomit

    2017-06-06

    The study was inspired after the authors encountered a patient with a penetrating globe injury due to drywall, who had retained intraocular drywall foreign body. Computed tomography (CT) was read as normal in this patient. Open globe injury with drywall has never been reported previously in the literature and there are no previous studies describing its radiographic features. The case report is described in detail elsewhere. This was an experimental study. An ex vivo model of 15 porcine eyes with 1 mm to 5 mm fragments of implanted drywall, 2 vitreous only samples with drywall and 3 control eyes were used. Eyes and vitreous samples were CT scanned on Days 0, 1, and 3 postimplantation. Computed ocular images were analyzed by masked observers. Size and radiodensity of intraocular drywall were measured using Hounsfield units (HUs) over time. Intraocular drywall was hyperdense on CT. All sizes studied were detectable on Day 0 of scanning. Mean intraocular drywall foreign body density was 171 ± 52 Hounsfield units (70-237) depending on fragment size. Intraocular drywall foreign body decreased in size whereas Hounsfield unit intensity increased over time. Drywall dissolves in the eye and becomes denser over time as air in the drywall is replaced by fluid. This study identified Hounsfield Units specific to intraocular drywall foreign body over time.

  19. A case of Alagille syndrome complicated by intraocular lens subluxation and rhegmatogenous retinal detachment

    Directory of Open Access Journals (Sweden)

    Fukumoto M

    2013-07-01

    Full Text Available Masanori Fukumoto, Tsunehiko Ikeda, Tetsuya Sugiyama, Mari Ueki, Takaki Sato, Eisuke Ishizaki Department of Ophthalmology, Osaka Medical College, Takatsuki City, Japan Abstract: This case report describes a case of Alagille syndrome with developing intraocular lens subluxation and rhegmatogenous retinal detachment 4 years after cataract surgery. A 15-year-old female patient with Alagille syndrome-associated cataracts in both eyes underwent phacoemulsification aspiration and intraocular lens implantation. Four years postoperative, intraocular lens subluxation developed in her left eye. For treatment, extraction of the dislocated intraocular lens, anterior vitrectomy, and intraocular lens fixation was performed. Three weeks later, the patient developed rhegmatogenous retinal detachment, which was well-treated by pars plana vitrectomy. Cataract surgery needs to be performed carefully in patients with Alagille syndrome due to the weakness of the zonule of Zinn. Careful postoperative observation is necessary for patients with Alagille syndrome who have undergone intraocular surgery in order to facilitate early detection of a possible rhegmatogenous retinal detachment. Keywords: Alagille syndrome, cataract, retina, surgery

  20. El sistema endocannabinoide: una ventana al uso terapeútico del cannabis

    OpenAIRE

    Rodríguez de Fonseca, Fernando

    2017-01-01

    Desde hace unos años venimos asistiendo a debates vivos sobre las cualidades terapéuticas del cannabis como pueden ser la analgesia, disminución de la presión intraocular, efecto antiemético en vómitos inducidos por quimioterapia antineoplásica, propiedades relajantes musculares en diversas enfermedades como esclerosis múltiple, traumatismos medulares y alteraciones del movimiento, etc… dando lugar a movimientos sociales pro-cultura del cannabis a través del cual se potencia su uso como una d...

  1. Reliable intraocular pressure measurement using automated radio-wave telemetry

    Directory of Open Access Journals (Sweden)

    Paschalis EI

    2014-01-01

    Full Text Available Eleftherios I Paschalis,* Fabiano Cade,* Samir Melki, Louis R Pasquale, Claes H Dohlman, Joseph B CiolinoMassachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA*These authors contributed equally to this workPurpose: To present an autonomous intraocular pressure (IOP measurement technique using a wireless implantable transducer (WIT and a motion sensor.Methods: The WIT optical aid was implanted within the ciliary sulcus of a normotensive rabbit eye after extracapsular clear lens extraction. An autonomous wireless data system (AWDS comprising of a WIT and an external antenna aided by a motion sensor provided continuous IOP readings. The sensitivity of the technique was determined by the ability to detect IOP changes resulting from the administration of latanoprost 0.005% or dorzolamide 2%, while the reliability was determined by the agreement between baseline and vehicle (saline IOP.Results: On average, 12 diurnal and 205 nocturnal IOP measurements were performed with latanoprost, and 26 diurnal and 205 nocturnal measurements with dorzolamide. No difference was found between mean baseline IOP (13.08±2.2 mmHg and mean vehicle IOP (13.27±2.1 mmHg (P=0.45, suggesting good measurement reliability. Both antiglaucoma medications caused significant IOP reduction compared to baseline; latanoprost reduced mean IOP by 10% (1.3±3.54 mmHg; P<0.001, and dorzolamide by 5% (0.62±2.22 mmHg; P<0.001. Use of latanoprost resulted in an overall twofold higher IOP reduction compared to dorzolamide (P<0.001. Repeatability was ±1.8 mmHg, assessed by the variability of consecutive IOP measurements performed in a short period of time (≤1 minute, during which the IOP is not expected to change.Conclusion: IOP measurements in conscious rabbits obtained without the need for human interactions using the AWDS are feasible and provide reproducible results.Keywords: IOP, pressure transducer, wireless, MEMS, implant, intraocular

  2. Role of TLR5 and flagella in bacillus intraocular infection.

    Directory of Open Access Journals (Sweden)

    Salai Madhumathi Parkunan

    Full Text Available B. cereus possesses flagella which allow the organism to migrate within the eye during a blinding form of intraocular infection called endophthalmitis. Because flagella is a ligand for Toll-like receptor 5 (TLR5, we hypothesized that TLR5 contributed to endophthalmitis pathogenesis. Endophthalmitis was induced in C57BL/6J and TLR5-/- mice by injecting 100 CFU of B. cereus into the mid-vitreous. Eyes were analyzed for intraocular bacterial growth, retinal function, and inflammation by published methods. Purified B. cereus flagellin was also injected into the mid-vitreous of wild type C57BL/6J mice and inflammation was analyzed. TLR5 activation by B. cereus flagellin was also analyzed in vitro. B. cereus grew rapidly and at similar rates in infected eyes of C57BL/6J and TLR5-/- mice. A significant loss in retinal function in both groups of mice was observed at 8 and 12 hours postinfection. Retinal architecture disruption and acute inflammation (neutrophil infiltration and proinflammatory cytokine concentrations increased and were significant at 8 and 12 hours postinfection. Acute inflammation was comparable in TLR5-/- and C57BL/6J mice. Physiological concentrations of purified B. cereus flagellin caused significant inflammation in C57BL/6J mouse eyes, but not to the extent of that observed during active infection. Purified B. cereus flagellin was a weak agonist for TLR5 in vitro. These results demonstrated that the absence of TLR5 did not have a significant effect on the evolution of B. cereus endophthalmitis. This disparity may be due to sequence differences in important TLR5 binding domains in B. cereus flagellin or the lack of flagellin monomers in the eye to activate TLR5 during infection. Taken together, these results suggest a limited role for flagellin/TLR5 interactions in B. cereus endophthalmitis. Based on this and previous data, the importance of flagella in this disease lies in its contribution to the motility of the organism within the

  3. Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility

    OpenAIRE

    Chintalapudi, Sumana R.; Maria, Doaa; Di Wang, Xiang; Bailey, Jessica N. Cooke; Hysi, Pirro G.; Wiggs, Janey L.; Williams, Robert W.; Jablonski, Monica M.

    2017-01-01

    textabstractGlaucoma is a multi-factorial blinding disease in which genetic factors play an important role. Elevated intraocular pressure is a highly heritable risk factor for primary open angle glaucoma and currently the only target for glaucoma therapy. Our study helps to better understand underlying genetic and molecular mechanisms that regulate intraocular pressure, and identifies a new candidate gene, Cacna2d1, that modulates intraocular pressure and a promising therapeutic, pregabalin, ...

  4. African Ancestry Is Associated with Higher Intraocular Pressure in Latinos.

    Science.gov (United States)

    Nannini, Drew; Torres, Mina; Chen, Yii-Der I; Taylor, Kent D; Rotter, Jerome I; Varma, Rohit; Gao, Xiaoyi

    2016-01-01

    Intraocular pressure (IOP) is a major risk factor, as well as the only modifiable risk factor, for glaucoma. Racial differences have been observed in IOP measurements with individuals of African descent experiencing the highest IOP when compared with other ethnic groups. The purpose of this study was to examine the relationship between genetic ancestry and IOP in Latinos. Population-based genetic association study. A total of 3541 participants recruited from the Los Angeles Latino Eye Study. Study participants were genotyped using the Illumina OmniExpress BeadChip (∼730K markers). We used STRUCTURE to estimate individual genetic ancestry. Simple and multiple linear regression, as well as quantile regression, analyses were performed to investigate the relationship between genetic ancestry and IOP. The relationship between genetic ancestry and IOP in Latinos. African ancestry was significantly associated with higher IOP in Latinos in our simple linear regression analysis (P = 0.002). After adjusting for age, gender, body mass index, systolic blood pressure, central corneal thickness, and type 2 diabetes, this association remained significant (P = 0.0005). The main association was modified by a significant interaction between African ancestry and hypertension (P = 0.037), with hypertensive individuals experiencing a greater increase in IOP with increasing African ancestry. To our knowledge, we demonstrate for the first time that African ancestry and its interaction with hypertension are associated with higher IOP in Latinos. Copyright © 2016 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  5. Iris color and intraocular pressure: the Blue Mountains Eye Study.

    Science.gov (United States)

    Mitchell, Robert; Rochtchina, Elena; Lee, Anne; Wang, Jie Jin; Mitchell, Paul

    2003-03-01

    To assess the relationship between iris color and intraocular pressure (IOP). Population-based, cross-sectional study. The Blue Mountains Eye Study examined 3,654 largely Caucasian participants, aged 49 to 97 years, from 1992 to 1994. Information was collected about glaucoma risk factors, and Goldmann applanation IOP measurements were taken. Iris color was assessed by comparing the undilated appearance of each eye with three standard photographs. Participants who had previous cataract or glaucoma surgery and those using glaucoma medications were excluded. Mean IOP measurements increased with increasing grades of iris pigmentation. After simultaneous adjustment for variables associated with IOP, mean measurements were 15.92 mm Hg for blue iris color, 16.04 mm Hg for hazel or green, 16.11 mm Hg for tan-brown, and 16.49 mm Hg for dark brown (P for trend = .001). This study demonstrates a modest but statistically significant association between increasing iris color and IOP. Copyright 2003 by Elsevier Science Inc.

  6. Effect of four different intraocular lenses on posterior capsule opacification.

    Science.gov (United States)

    Duman, Rahmi; Karel, Fatih; Özyol, Pelin; Ateş, Can

    2015-01-01

    To evaluate the impact of 4 different intraocular lenses (IOLs) on posterior capsule opacification (PCO) by comparing the neodymium: yttrium-aluminum-garnet (Nd:YAG) laser capsulotomy rates. This retrospective study included 4970 eyes of 4013 cataract patients who underwent phacoemulsification and IOL implantation between January 2000 and January 2008 by the same surgeon at one clinic. Four different IOLs were assessed. The outcome parameter was the incidence of Nd:YAG laser posterior capsulotomies. An Nd:YAG laser posterior capsulotomy was performed in 153 (3.07%) of the 4970 eyes. The mean follow-up time was 84mo for all of the IOL groups. The percentage of eyes developing PCO was significantly greater for the acrylic hydrophilic IOLs than for the hydrophobic IOLs, although eyes with acrylic hydrophilic IOLs did not require Nd:YAG laser capsulotomy as soon as eyes with acrylic hydrophobic IOLs. There was no difference between the long-term PCO rates when 1- and 3-piece acrylic hydrophobic IOLs were compared or when IOLs made of the same material but with different haptic angles were compared. In this study, eyes with acrylic hydrophilic IOLs were more likely to develop PCO than those with acrylic hydrophobic IOLs. The lens design (1-piece versus 3-piece and varying haptic angles) did not affect the PCO rate.

  7. Measurement of rabbit intraocular pressure with the Tono-Pen.

    Science.gov (United States)

    Mermoud, A; Baerveldt, G; Minckler, D S; Lee, M B; Rao, N A

    1995-01-01

    A Tono-Pen-1 (TP-1) and a Tono-Pen-2 (TP-2) were calibrated against direct manometry in the eyes of living rabbits to determine the accuracy of the Tono-Pen. Eighteen normal eyes of 10 rabbits were cannulated and connected to a pressure transducer with a chart recorder. Intraocular pressure (IOP) was increased from 5 to 40 mm Hg in 5-mm-Hg increments and from 40 to 80 mm Hg in 10-mm-Hg increments. After each incremental increase, IOP was measured first with a TP-1 and then with a TP-2. Plotting the mean Tono-Pen readings for each eye against the transducer pressure produced the following two regression line formulas: y = -0.613+0.790x (r2 = 0.97) for TP-1, and y = -1.45+0.824x (r2 = 0.97) for TP-2. Neither regression line was statistically different; p = 0.2 for the two slopes, and p = 0.24 for the y-axis intersection. The TP-1 and TP-2 can be used to rapidly and accurately measure the IOP in normal rabbit eyes. Tono-Pen readings do, however, significantly underestimate pressures in the range of 5-80 mm Hg. A table with 95% confidence intervals for corrected IOP readings obtained with the TP-1 or -2 is provided.

  8. Retinal images in the human eye with implanted intraocular lens

    Science.gov (United States)

    Zając, Marek; Siedlecki, Damian; Nowak, Jerzy

    2007-04-01

    A typical proceeding in cataract is based on the removal of opaque crystalline lens and inserting in its place the artificial intraocular lens (IOL). The quality of retinal image after such procedure depends, among others, on the parameters of the IOL, so the design of the implanted lens is of great importance. An appropriate choice of the IOL material, especially in relation to its biocompatibility, is often considered. However the parameter, which is often omitted during the IOL design is its chromatic aberration. In particular lack of its adequacy to the chromatic aberration of a crystalline lens may cause problems. In order to fit better chromatic aberration of the eye with implanted IOL to that of the healthy eye we propose a hybrid - refractive-diffractive IOL. It can be designed in such way that the total longitudinal chromatic aberration of an eye with implanted IOL equals the total longitudinal chromatic aberration of a healthy eye. In this study we compare the retinal image quality calculated numerically on the basis of the well known Liou-Brennan eye model with typical IOL implanted with that obtained if the IOL is done as hybrid (refractive-diffractive) design.

  9. INTRAOCULAR LENS POSITION IN COMBINED PHACOEMULSIFICATION AND VITREORETINAL SURGERY.

    Science.gov (United States)

    Ozates, Serdar; Kiziltoprak, Hasan; Koc, Mustafa; Uzel, Mehmet Murat; Teke, Mehmet Yasin

    2017-10-09

    To assess the decentration and angle of tilt of the intraocular lens (IOL) according to the intravitreal tamponade types used in combined phacoemulsification and vitreoretinal surgery. This prospective and randomized clinical study involved 73 eyes of 69 patients who underwent combined vitreoretinal surgery. Eyes with intravitreal tamponades formed the study group and eyes without intravitreal tamponades formed the control group. The study group was further divided into silicone oil and gas tamponade subgroups. Cross-sectional IOL images were captured using a Pentacam HR (Oculus, Germany) and tilt and decentration were calculated with Adobe Photoshop software (Adobe, San Jose, CA). The mean angle of tilt and decentration at the vertical meridian were significantly higher in both tamponade groups than in the control group (P 0.05). When comparing the silicone oil and gas tamponade subgroups, no significant differences were noted on the position of IOL at both meridians (P > 0.05 for all). Intravitreal tamponades have an important effect on the position of IOL in combined vitreoretinal surgery. Silicone oil and gas tamponades may induce postoperative tilt and decentration of one-piece acrylic IOLs.

  10. Aerobic exercise and intraocular pressure in normotensive and glaucoma patients

    Directory of Open Access Journals (Sweden)

    Chatzibalis Theodosios

    2009-08-01

    Full Text Available Abstract Background With the increasing number of people participating in physical aerobic exercise, jogging in particular, we considered that it would be worth knowing if there are should be limits to the exercise with regard to the intraocular pressure (IOP of the eyes. The purpose of this study is to check IOP in healthy and primary glaucoma patients after aerobic exercise. Methods 145 individuals were subdivided into seven groups: normotensives who exercised regularly (Group A; normotensives in whose right eye (RE timolol maleate 0.5% (Group B, latanoprost 0.005% (Group C, or brimonidine tartrate 0.2% (Group D was instilled; and primary glaucoma patients under monotherapy with β-blockers (Group E, prostaglandin analogues (Group F or combined antiglaucoma treatment (Group G instilled in both eyes. The IOP of both eyes was measured before and after exercise. Results A statistically significant decrease was found in IOP during jogging. The aerobic exercise reduces the IOP in those eyes where a b-blocker, a prostaglandin analogue or an α-agonist was previously instilled. The IOP is also decreased in glaucoma patients who are already under antiglaucoma treatment. Conclusion There is no ocular restriction for simple glaucoma patients in performing aerobic physical activity.

  11. Toric intraocular lenses--theory, matrix calculations, and clinical practice.

    Science.gov (United States)

    Langenbucher, Achim; Viestenz, Anja; Szentmáry, Nóra; Behrens-Baumann, Wolfgang; Viestenz, Arne

    2009-07-01

    To describe 1) how to determine toric (posterior chamber) intraocular lenses (IOLs) with standard formulas, 2) a matrix-based calculation scheme for determining toric IOLs using 4x4 matrices, 3) a method to determine residual refraction after implantation of an arbitrary toric lens, and 4) to address clinical aspects. Formulas and metrics are reviewed for determining IOL power and residual refraction after toric IOL implantation. From 4x4 refraction and translation matrices characterizing refractive surfaces and interspaces between refractive surfaces, a system matrix is determined characterizing the entire optical system paraxially. Toric posterior chamber IOLs are determined by solving a linear equation system. In a second step, the same methodology is used for estimation of the residual refraction at the spectacle plane after implantation of an arbitrary toric lens. The methodology is applied to working examples, and the calculation procedure is described in a step-by-step approach. A straight-forward en bloc concept is demonstrated for determination of toric IOLs and estimation of the residual refraction. The applicability is shown in working examples, and clinical aspects such as rotation of the lens implant are addressed.

  12. Foldable toric intraocular lens for astigmatism correction in cataract patients.

    Science.gov (United States)

    Mendicute, Javier; Irigoyen, Cristina; Aramberri, Jaime; Ondarra, Ana; Montés-Micó, Robert

    2008-04-01

    To evaluate the results of AcrySof toric intraocular lens (IOL) (Alcon) implantation to correct preexisting astigmatism in patients having cataract surgery. Ophthalmology Service, Donostia Hospital, San Sebastián, Spain. This prospective observational study included 30 eyes of 15 consecutive patients with more than 1.00 diopter (D) of preexisting corneal astigmatism having cataract surgery. Bilateral implantation of the AcrySof toric IOL was performed after phacoemulsification. The uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), residual refractive sphere, residual keratometric and refractive cylinders, and toric IOL axis were measured. The UCVA was 20/40 or better in 93.3% of eyes and 20/25 or better in 66.6%. All eyes achieved 20/25 or better BCVA. The mean refractive cylinder decreased significantly after surgery from -2.34 D +/- 1.28 (SD) to -0.72 +/- 0.43 D (P<.01). Vector analysis of attempted versus achieved correction showed that 100% of eyes were within +/-1.00 D and 80% and 93.9% were within +/-0.50 D for J(0) and J(45), respectively. The mean toric IOL axis rotation was 3.63 +/- 3.11 degrees, with rotation less than 10 degrees in 96.7% of eyes. The results indicate that phacoemulsification and posterior chamber AcrySof toric IOL implantation is an effective option to correct preexisting astigmatism in cataract surgery. The AcrySof toric IOL showed good rotational stability.

  13. Enalaprilat and enalapril maleate eyedrops lower intraocular pressure in rabbits.

    Science.gov (United States)

    Loftsson, Thorsteinn; Thorisdóttir, Sigridur; Fridriksdóttir, Hafrun; Stefánsson, Einar

    2010-05-01

    This study aimed to develop low-viscosity aqueous eyedrops containing enalaprilat and its prodrug enalapril maleate in solution, and to evaluate the eyedrops in rabbits. Aqueous eyedrops with hydroxypropyl-beta-cyclodextrin containing 0.01-2.9% (w/v) enalaprilat, 1.0% (w/v) enalapril maleate with cyclodextrin or 0.5% (w/v) timolol were prepared. The eyedrops were administered to rabbits and intraocular pressure (IOP) was measured at various time intervals after the administration and the results (mean of 10 experiments +/- standard error of the mean) are expressed as the change from baseline (24.7 +/- 3.3 mmHg). Enalaprilat possessed sufficient stability to be formulated as an aqueous eyedrop solution with a shelf-life of several years at room temperature. The maximum decline in IOP after topical administration of one drop of 2.9% enalaprilat solution was 6.2 +/- 0.7 mmHg at 4 hours after administration. Duration of activity exceeded 10 hours. A 1% enalaprilat solution lowered IOP by 4.4 +/- 0.8 mmHg at 4 hours after administration and had similar duration, and was more potent than 0.5% timolol. The enalapril maleate eyedrops resulted in delayed action, showing maximum potency at 10-22 hours after administration and duration of up to 32 hours. Enalaprilat eyedrops lower IOP in rabbits. The decline in IOP is proportional to the concentration of dissolved enalaprilat in low-viscosity aqueous eyedrop formulations.

  14. [Reasons for exchange and explantation of intraocular lenses].

    Science.gov (United States)

    Neuhann, I; Fleischer, F; Neuhann, T

    2012-08-01

    This study was performed to analyse the reasons for explantation/exchange of intraocular lenses (IOL), which had originally been implanted for the correction of aphakia during cataract extraction. All cases with IOL explantation, which had been performed at one institution between 1/2008 and 12/2009 were analysed retrospectively. A total of 105 eyes of 100 patients were analysed. The median time interval between implantation and explantation of the IOL was 5.9 years (min. 0, max. 29.6). The most frequent cause for the intervention was subluxation/dislocation of the implant in 55.2% of cases. This group comprised 21% of cases with subluxation within the capsular bag in pseudoexfoliation syndrome. Other reasons were optical problems/incorrect IOL power (21%), calcification of hydrophilic acrylic IOL (7.6%), corneal decompensation associated with an anterior chamber lens (4.8%), and single cases with varying problems. The reasons for IOL exchange presented in this study are comparable to those of other series in the literature. Explantations due to optical problems may gain weight in the future due to a rise in refractive procedures and demands. © Georg Thieme Verlag KG Stuttgart · New York.

  15. Motorized injector-assisted intrascleral intraocular lens fixation.

    Science.gov (United States)

    Hung, Jia-Horung; Wang, Shih-Hao; Teng, Yu-Ti; Hsu, Sheng-Min

    2017-03-01

    For eyes with deficient capsular support, intraocular lens (IOL) implantation has long been a technical challenge. Recently, intrascleral fixation of the haptics of a three-piece posterior chamber IOL has become a popular option. In this procedure, externalization of the leading haptic during IOL injection is a stressful step. We present a modified technique to improve the ease and safety of this step. Our modified technique involves IOL injection with a motorized injector with several important modifications described here. With these modifications, a surgeon can easily maintain the correct orientation of the IOL in a well-controlled manner during IOL injection. The records of 13 patients who underwent this technique were retrospectively evaluated. Corrected-distance visual acuity improved significantly after surgery (pIOL decentration, or vitreous hemorrhage was noted during the follow-up period. In conclusion, the motorized injector-assisted intrascleral IOL fixation technique is a safe and effective alternative to the conventional procedure. This technique makes the process of leading haptic externalization easier and more controllable. Copyright © 2017. Published by Elsevier Taiwan.

  16. Single-suture scleral fixation of subluxated foldable intraocular lenses.

    Science.gov (United States)

    Yarangumeli, Alper; Alp, Mehmet Numan; Kural, Gulcan

    2012-01-01

    To evaluate the results of single-suture scleral fixation of subluxated foldable intraocular lenses (IOL) in eyes with sufficient residual capsular support. The results of IOL repositioning by single-suture scleral fixation in 6 eyes of 6 patients with IOL subluxation were included. All subluxated IOLs were single-piece hydrophilic acrylic. Subluxation resulted from posterior capsule tears in 3 eyes, zonular dialyses in 2 eyes, and zonular dialysis with a capsulorhexis tear in 1 eye. A similar technique was used in all eyes in which one haptic was externalized through a superior clear corneal incision and tied with a Pair-PAK 10-0 polypropylene suture, and was finally retracted and fixated behind the iris close to the ciliary sulcus at the 12:00 meridian. All patients were followed up for at least 6 months. Best-corrected visual acuities ranged between finger counting and 20/70 (mean logMAR 1.02±0.64) preoperatively, and between 20/100 and 20/20 (mean logMAR 0.22±0.26) at the final postoperative visit. All IOLs remained centered and no significant postoperative complications were encountered except for an IOL tilt which resulted in a considerable oblique astigmatism in one eye. Subluxated foldable IOLs may safely be repositioned and secured with a single scleral fixation suture in selected cases with adequate amount of capsular remnants.

  17. Bioptics in sutureless intrascleral multifocal posterior chamber intraocular lens fixation.

    Science.gov (United States)

    Pavlidis, Mitrofanis; de Ortueta, Diego; Scharioth, Gabor B

    2011-05-01

    To present a technique for sutureless fixation of a three-piece, multifocal, posterior chamber intraocular lens (IOL) in the ciliary sulcus. A 24-year-old woman presented with bilateral subluxation of the crystalline lens. Two straight sclerotomies were prepared with a 24-gauge cannula 2.0 mm from the limbus 180° apart from each other. The cannula was used to create a 2.0- to 3.0-mm tunnel parallel to the limbus starting from the sclerotomies. The leading haptic of the multifocal IOL was grasped at its tip with end-gripping, 25-gauge forceps and pulled through the sclerotomy. The forceps was used to introduce the IOL haptic into the scleral tunnel parallel to the limbus. Multifocal posterior chamber IOLs were stable and well centered. No postoperative complications occurred in the 16-month follow-up period. Preoperative astigmatism was corrected after IOL implantation with corneal wavefront-guided laser epithelial keratomileusis. Sutureless fixation of multifocal posterior chamber IOL haptics in a scleral tunnel parallel to the limbus can be successful, resulting in long-term centration and three-dimensional axial stability for optimal refractive results. If necessary, postoperative wavefront-guided refractive correction can be performed to optimize final refraction. Copyright 2011, SLACK Incorporated.

  18. Motorized injector-assisted intrascleral intraocular lens fixation

    Directory of Open Access Journals (Sweden)

    Jia-Horung Hung

    2017-03-01

    Full Text Available For eyes with deficient capsular support, intraocular lens (IOL implantation has long been a technical challenge. Recently, intrascleral fixation of the haptics of a three-piece posterior chamber IOL has become a popular option. In this procedure, externalization of the leading haptic during IOL injection is a stressful step. We present a modified technique to improve the ease and safety of this step. Our modified technique involves IOL injection with a motorized injector with several important modifications described here. With these modifications, a surgeon can easily maintain the correct orientation of the IOL in a well-controlled manner during IOL injection. The records of 13 patients who underwent this technique were retrospectively evaluated. Corrected-distance visual acuity improved significantly after surgery (p<0.05. No postoperative retinal detachment, endophthalmitis, IOL decentration, or vitreous hemorrhage was noted during the follow-up period. In conclusion, the motorized injector-assisted intrascleral IOL fixation technique is a safe and effective alternative to the conventional procedure. This technique makes the process of leading haptic externalization easier and more controllable.

  19. Intraocular lens dislocation after whole-body vibration.

    Science.gov (United States)

    Vela, José I; Andreu, David; Díaz-Cascajosa, Jesús; Buil, José A

    2010-10-01

    We present 2 cases of intraocular lens (IOL) dislocation that appeared shortly after the patients exercised on a vibration platform. The first patient was a 71-year-old woman who presented with lens subluxation in her right eye and a complete posterior IOL dislocation in her left eye. The second case was a 62-year-old woman who presented with unilateral IOL dislocation within the capsular bag in her right eye. Timing from IOL implantation to dislocation was approximately 6 years and 4 years, respectively. Pars plana vitrectomy with removal of the dislocated IOL was performed in both patients. Whole-body vibration training has become increasingly popular as a form of exercise training. It reportedly may provide benefits in physical function and in some diseases, especially in older people. However, evidence-based protocols ensuring safety and efficacy in this population are lacking. We discuss vibration as a cause of late IOL dislocation. Copyright © 2010 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  20. Intermediate results of sutureless intrascleral posterior chamber intraocular lens fixation.

    Science.gov (United States)

    Scharioth, Gabor B; Prasad, Som; Georgalas, Ilias; Tataru, Calin; Pavlidis, Mitrofanis

    2010-02-01

    To report the intermediate multicenter results of a technique of sutureless intrascleral fixation of a standard 3-piece posterior chamber intraocular lens (PC IOL) in the ciliary sulcus. Four European ophthalmology centers. A technique for sutureless intrascleral fixation of the haptics of a standard 3-piece PC IOL was retrospectively evaluated. The technique uses standardized maneuvers to fixate the PC IOL without need for special haptic architecture or preparation or haptic suturing. All patients having IOL implantation by the technique were evaluated for preoperative status (visual acuity, refractive error, preexisting ocular conditions, optical biometry), postoperative status, complications, and need for further surgery. The study evaluated 63 consecutive patients from 4 institutions (4 surgeons). The median follow-up was 7 months. Two dislocated PC IOLs (3.6%) were decentered; the other 61 IOLs (96.8%) were stable and well centered. There were no cases of recurrent dislocation, endophthalmitis, retinal detachment, or glaucoma. Fixation of PC IOL haptics in a limbus-parallel scleral tunnel provided exact centration and axial stability of the IOL and prevented distortion and subluxation in most cases. Copyright 2010 ASCRS and ESCRS. All rights reserved.

  1. Scleral Fixation of a One-Piece Toric Intraocular lens

    Science.gov (United States)

    Emanuel, Matthew E.; Randleman, J. Bradley; Masket, Samuel

    2013-01-01

    Purpose To describe a novel technique for toric intraocular lens (IOL) repositioning and fixation in the absence of adequate capsular support Methods Case report and literature review Results Two cases are presented with scleral fixation of a one-piece toric IOL (SN6AT series, Alcon Inc.) In both cases, toric IOLs initially placed within the capsular bag became decentered due to poor capsular support and/or posterior capsule rupture. To avoid the potential complications of lens explantation and maintain the astigmatic benefits of the toric IOL, scleral fixation of the lenses was performed. The Hoffman technique was used to create reverse scleral pockets without conjunctival dissection. A 10-0 suture was used to capture and then secure the lens haptics in a lasso-type fashion. Sutures were then buried within the previously created scleral pockets. Both patients had well centered lenses postoperatively and have remained stable at last follow-up, up to thirty months postoperatively. Conclusion In the absence of adequate capsular support, scleral fixation is a viable option for one-piece toric IOL fixation to avoid IOL explanation PMID:23380416

  2. Pharmacotherapy of intraocular pressure: part I. Parasympathomimetic, sympathomimetic and sympatholytics.

    Science.gov (United States)

    Costagliola, Ciro; dell'Omo, Roberto; Romano, Mario R; Rinaldi, Michele; Zeppa, Lucia; Parmeggiani, Francesco

    2009-11-01

    Elevated intraocular pressure (IOP) has been recognized as the major risk factor for the development of glaucoma and a wide range of options are now available to reduce it: medical treatment, laser, filtering, or cyclodestructive surgery (alone or in combination). All these modalities act by decreasing eye pressure and, thereby, protecting the optic nerve head from a mechanic direct and/or vascular indirect insult. Topical medical therapy represents the first-choice treatment and, in most cases, it effectively controls IOP, avoiding the occurrence of further optic nerve damage. All medications lower IOP in two main ways: decreasing the production of aqueous humour or by increasing its outflow from the eye. Consequently, antiglaucoma drugs either suppress aqueous humour formation (beta-adrenergic antagonists, carbonic anhydrase inhibitors, and alpha-2-adrenergic agonists) or raise aqueous humour outflow throughout the conventional (e.g., pilocarpine) or uveoscleral (prostaglandin FP receptor agonists, and prostamides) route. In addition, fixed and unfixed combinations of antiglaucoma compounds have also been available for patients requiring more than one type of medication. This review, which is part one of two (please see Expert Opinion on Pharmacotherapy 10 (17)) briefly considers the characteristics of sympathomimetic, sympatholytics and parasympathomimetic commonly employed in the medical treatment of glaucoma, mainly the primary open-angle form, focusing the discussion on the clinical evidence supporting the use of these three classes of compound.

  3. The Effect of Aerobic Exercise on Intraocular Pressure in Horse

    Directory of Open Access Journals (Sweden)

    Elisabetta Giudice

    2010-01-01

    Full Text Available The present study was planned to investigate the effect of the intensity of exercise on intraocular pressure (IOP, systolic and diastolic blood pressure, glycaemia and blood lactate concentration in regularly trained Italian saddle jumper horses. On the first day five female horses performed 1 h of walking on an electronically controlled horse-walker at 100 m/min; on the second day 1 h session consisted of 5 min of walk, 30 min of trot, 20 min of gallop and one exercise of a 300 m long trail with eight jumps 90 cm high to be run in 1 min. The studied indicators were collected at rest, immediately after the exercise and 30 min after the exercise. Analysis of variance (ANOVA showed a significant effect of different workloads on blood lactate concentration, systolic and diastolic blood pressure. No significant difference was found in IOP reduction when comparing aerobic and moderate anaerobic exercise. Our results confirm that the lack of a significant change in IOP in the athletic horse after mild exercise is in accordance with the human athlete. The cardiovascular and haematological changes induced by aerobic and moderate anaerobic exercise had no significant effect on IOP, either.

  4. Bilateral implantation of +2.5 D multifocal intraocular lens and contralateral implantation of +2.5 D and +3.0 D multifocal intraocular lenses: Clinical outcomes

    NARCIS (Netherlands)

    Nuijts, Rudy M. M. A.; Jonker, Soraya M. R.; Kaufer, Robert A.; Lapid-Gortzak, Ruth; Mendicute, Javier; Martinez, Cristina Peris; Schmickler, Stefanie; Kohnen, Thomas

    2016-01-01

    To assess the clinical visual outcomes of bilateral implantation of Restor +2.5 diopter (D) multifocal intraocular lenses (IOLs) and contralateral implantation of a Restor +2.5 D multifocal IOL in the dominant eye and Restor +3.0 D multifocal IOL in the fellow eye. Multicenter study at 8

  5. Macroglobulinemia de Waldenström com hemorragia intra-ocular Waldenström's macroglobulinaemia with intraocular hemorrhage

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    João J. Nassaralla Júnior

    2006-12-01

    Full Text Available O objetivo deste trabalho é relatar um caso de macroglobulinemia de Waldenström com envolvimento retiniano e da circulação coroidiana, com boa resposta ao tratamento. O desenho é um caso controle intervencional. Um homem de 47 anos foi encaminhado para o serviço de hematologia para avaliação de anemia e linfadenopatia inguinal. O diagnóstico de macroglobulinemia de Waldenström foi feito com base nos achados clínicos e laboratoriais. O paciente desenvolveu hemorragia intra-ocular sem associação com hipertensão e com fatores de coagulação normais. Exame fundoscópico revelou retardamento na circulação coriorretiniana, microaneurismas, e telangiectasias no pólo posterior. Angiografia fluorescente demonstrou o prolongamento do tempo da circulação coroidiana, tempo de trânsito arteriovenoso também prolongado, e áreas de não perfusão capilar. Estes resultados foram acompanhados por uma elevação acentuada da IgM. A maioria dos achados oculares foi revertida com a plasmaférese. A macroglobulinemia de Waldenström pode envolver a retina e a circulação coroidiana, porém pode ser reversível com o tratamento apropriado.The aim of this work is to report a case of Waldenström's Macroglobulinaemia involving both retinal and choroidal circulation that resolved after treatment. The design is an interventional case report. A 47-year old male was admitted for evaluation of anaemia, and groin lymphadenopathy. A diagnosis of Waldenström's macroglobulinaemia was made based on clinical and laboratory findings. The patient developed intraocular hemorrhage without associated hypertension and with normal coagulation profile. A funduscopic examination revealed marked dilation and beading of the venous system, microaneurysms, and telangiectatic capillary beds in the posterior pole. A fluorescein angiography showed delayed choroidal filling, prolonged arteriovenous transit time and areas of capillary non-perfusion. These findings were

  6. The influence of retrobulbar adipose tissue volume upon intraocular pressure in obesity

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    Stojanov Oliver

    2013-01-01

    Full Text Available Background/Aim. It is known that glaucoma is associated with elevated intraocular pressure and obesity, yet the precise etiology remains unclear. The aim of this study was to determine whether there is a potential causality between the volume of retrobulbar adipose tissue and the level of intraocular pressure in obese subjects compared with non-obese. Methods. A total of 100 subjects were divided according to the body mass index (BMI, into two groups: normal weight (n = 50, BMI = 18-24.9 kg/m2 and obese (n = 50, BMI ≥ 30 kg/m2 subjects. Anthropometric measurements, body composition analysis, measurement of intraocular pressure, as well as magnetic resonance imaging (MRI of the head at the level of the optic nerve, and the derived retrobulbar adipose tissue volume, were undertaken in all subjects. Results. The obese subjects, as compared with normal weight ones, had a significantly higher mean retrobulbar adipose tissue volume (6.23 cm3 vs 4.85 cm3, p < 0.01 and intraocular pressure (15.96 mmHg vs 12.99 mmHg, p < 0.01. Furthermore, intraocular pressure correlated positively with retrobulbar adipose tissue volume. Conclusion. In obese people, elevated intraocular pressure may be caused by changes in ocular blood flow, affected by the physical pressure exerted by higher retrobulbar adiposity, and/or by internal vascular changes secondary to complications of obesity. These findings indicate the need for more frequent measurement of intraocular pressure in obese individuals to earlier detect glaucoma, and in so doing prevent irreversible blindness.

  7. Callus formation in vitro and internodal stem apices in savory = Calogênese in vitro de segmentos apicais caulinares e internodais em segurelha (Satureja hortensis L.

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    Marcio Carlos Navroski

    2012-12-01

    Full Text Available We sought to evaluate with this work different growth regulators on callus formation in shoot apical and internodal stem segments of Satureja hortensis. The explants were isolated from in vitro seedlings and cultured on MS nutrient medium supplemented with NAA (0 and 1 μM and BAP (0, 5, 10, 15 and 20 μM. The presence of auxin NAA gave higher marks to the calluses at 30 days of evaluation, these notes also increased with the addition of BAP. There were significant interactions between factors in evaluating NAA and BAP for 60 days, both in apical stem segments as in internodal stem segments. To stemapices percentage of friable callus tends to decrease with increasing concentration of BAP. As for compact calluses increased BAP leads to an increase in the percentage of this type of callus. The presence of NAA increased callus formation in both friable and compact calluses on. This trend was also observed in internodal stem segments. The callus formation was highly rhizogenic observed in the presence of NAA, hardly occurs in the absence of auxin. The use of BAP is recommended in case of regeneration of plants through micropropagation, if the goal is the production of metabolites, the use of BAP can be harmful by reducing the production of friable callus.= Buscou-se com este trabalho avaliar diferentes reguladores de crescimento sobre a calogênese em segmentos caulinares apicais e internodais de Satureja hortensis L.. Os explantes foram isolados de plântulas germinadas in vitro e cultivados em meio nutritivo MS acrescido de ANA (0 e 1 μM e de BAP (0; 5; 10; 15 e 20 μM. A presença da auxina ANA proporcionou notas mais altas para os calos aos 30 dias de avaliação, estas notas também aumentaram com o acréscimo da citocinina BAP. Houve interações significativas entre os fatores ANA e BAP na avaliação aos 60 dias, nos dois tipos de segmentos caulinares(apicais e internodais. Nos segmentos apicais caulinares a porcentagem de calos fri

  8. Ceratoconjuntivite alérgica e complicações no segmento ocular anterior de pacientes Evaluation of anterior ocular segment complications in patients with allergic keratoconjunctivitis

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    Patrícia Bezerra de Menezes Botelho

    2003-01-01

    Full Text Available INTRODUÇÃO: A alergia ocular é condição que pode ocasionar sintomas de coceira, ardor e lacrimejamento, podendo também ser ameaçadora para visão. A fisiopatologia envolve mecanismos de hipersensibilidade imunológica. Devido a fatores imunológicos, o segmento anterior destes pacientes está mais suscetível a alterações que ameaçam a acuidade visual, tais como: opacidades corneanas, ceratocone e catarata. MÉTODOS: Foram revistos, retrospectivamente, 186 pacientes com ceratoconjuntivite alérgica e selecionados pacientes que possuíam alterações de segmento anterior e acuidade visual menor ou igual a 0,6 corrigida em um ou ambos os olhos. A AV 0,6 foi escolhida aleatoriamente a fim de agrupar os pacientes. Estes pacientes foram analisados quanto à idade, sexo, tipo de alergia, tempo de aparecimento da doença (considerado como tempo de aparecimento de sintomas, tempo de latência (tempo que surgiu a complicação após o primeiro dia de atendimento, alterações sistêmicas, efeitos colaterais das drogas e complicações oculares. Estes pacientes não poderiam melhorar a AV com tratamento tópico e tinham acompanhamento mínimo de 3 meses. RESULTADOS: As alterações de segmento anterior que causaram AV menor ou igual a 0,6 (refração ou estenopeico sem possibilidade de melhora com medicação tópica foram: úlcera em escudo: 5 casos, catarata: 3 casos, opacidade corneana: 6 casos, perfuração ocular: 2 casos e ceratocone: 13 casos. CONCLUSÃO: Pacientes com ceratoconjuntivite alérgica podem ter como principais causas de baixa acuidade visual alterações de segmento anterior, entre elas, opacidades corneanas, ceratocone e catarata.PURPOSE: To evaluate complications of allergic keratoconjuctivitis that caused reduction in visual acuity to 0.6 or less and that could not solve with clinic treatment. METHODS: We analyzed retrospectively 186 charts and selected patients with visual acuity less than 0.6 on Snellen chart, associated

  9. A preferência da marca no processo de decisão de compra: um estudo exploratório no segmento de baixa renda

    OpenAIRE

    Karen Perrotta Lopes de Almeida Prado

    2008-01-01

    O aumento do poder aquisitivo das famílias de baixa renda no Brasil transformou esse público em um mercado atraente para as empresas de vários segmentos. Percebeu-se, contudo, que não está ainda refletida em conhecimento, na área de marketing, a relevância tanto econômica como social dessa parcela da população brasileira, uma vez que se verificou que há escassez de informações e de estudos sobre o tema. Nesse contexto, o objetivo nesta tese é investigar a preferência pela marca no processo de...

  10. ESTUDO SOBRE A UTILIZAÇÃO DE ATRIBUTOS DA IDENTIDADE CULTURAL BRASILEIRA COMO FONTE DE VANTAGEM COMPETITIVA NO SEGMENTO DE MODA

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    Mariana Bassi Sutter

    2015-06-01

    Full Text Available Este estudo procurou investigar se a Brasilidade na moda representa fonte de vantagem competitiva no segmento de moda. Buscou-se também, verificar se o consumidor consegue identificar e hierarquizar os atributos da Brasilidade na moda. Levantou-se o referencial teórico relacionado a fontes de vantagem competitiva, consumidor de moda e Brasilidade na moda. Para tanto conduzir o estudo, realizou-se uma survey. Para a coleta de dados elaborou-se um questionário estruturado com questões fechadas e fotos de vestuários. A amostra totalizou 411 respondentes selecionados por conveniência. Os resultados permitiram detectar que a Brasilidade na moda pode ser uma fonte de vantagem competitiva.

  11. Repressão e violência de Estado contra os segmentos populares durante os governos militares. Rivail Carvalho Rolim

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    Rivail Carvalho Rolim

    2015-11-01

    Full Text Available Inúmeras pesquisas analisaram variados aspectos acerca do exercício do poder durante o regime militar, destacando inclusive a repressão e a violência levada a cabo pelas forças repressivas contra os grupos políticos que se opuseram a esse regime. Contudo, depois de anos de pesquisas novos olhares começam a ser lançados sobre a ditadura no Brasil. Como havia uma concepção bastante ampla relativa às tensões e aos antagonismos existentes no país e com os segmentos sociais que poderiam provocá-las, este trabalho tem como objetivo analisar a violência do Estado contra as classes populares, tendo em vista que foram consideradas como portadoras de um potencial desagregador e perigoso e despreparadas para viver em uma sociedade moderna, industrializada e de vida marcadamente urbana.

  12. Relationship between homocysteine and intraocular pressure in men and women: A population-based study.

    Science.gov (United States)

    Leibovitzh, Haim; Cohen, Eytan; Levi, Amos; Kramer, Michal; Shochat, Tzippy; Goldberg, Elad; Krause, Ilan

    2016-09-01

    The relationship between homocysteine levels and glaucoma has been questioned in previous studies without conclusive results. In the current study, we assessed the relationship between homocysteine levels and intraocular pressure which is one of the main factors in the development of glaucoma in men and women.A retrospective cross-sectional analysis of a database from a screening center in Israel which assessed 11,850 subjects, within an age range 20 to 80 years. The relationship between homocysteine and intraocular pressure has been investigated by comparing intraocular pressure in subjects with elevated and normal homocysteine and by comparing homocysteine levels in subjects with elevated and normal intraocular pressure. In addition, we compared the levels of homocysteine in subjects with and without a confirmed diagnosis of glaucoma.The mean IOP (±SD) in subjects with normal homocysteine levels(≤15 μmol/L) was 13.2 ± 2.3 mm Hg and 13.4 ± 2.4 mm Hg in those with high homocysteine levels (>15 μmol/L) (P homocysteine levels (±SD) in subjects with normal intraocular pressure of ≤ 21 mm Hg was 11.7 ± 5.5 μmol/L and 12.09 ± 3.43 μmol/L in those with elevated intraocular pressure (P = 0.4, 95%CI 1.1-1.8). Mean homocysteine levels (±SD) in subjects with glaucoma were 11.2 ± 3.5 μmol/L compared to 11.7 ± 5.5 μmol/L in subjects without glaucoma and normal intraocular pressure ≤ 21 mm Hg (P = 0.4, 95% CI 1.2-2.1).The current study displays no clinical correlation between the homocysteine level and the intraocular pressure. Homocysteine may not be used as a predictive parameter to recognize those subjects prone to develop elevated intraocular pressure.

  13. Effect of phacoemulsification on vision and intraocular pressure and corneal astigmatism

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    Jing Yu

    2017-06-01

    Full Text Available Objective: To explore the effect of phacoemulsification in combined with intraocular lens implantation incision site selection on the visual function, intraocular pressure, and corneal astigmatism in patients with cataract. Methods: A total of 72 patients (85 eyes with cataract who were admitted in our hospital from April, 2015 to October, 2016 were included in the study. All the patients were performed with phacoemulsification in combined with intraocular lens implantation. The patients were divided into the observation group (n=36, 43 eyes and the control group (n=36, 42 eyes according to different surgical incision sites. A transparent corneal incision with a length of 3.0 mm was made along the meridian axial position with the maximum corneal refractive power in the observation, while a transparent corneal incision with a length of 3.0 mm was made above the temple or nose in the control group. Routine disposition and follow-up visit were given for the patients in the two groups after operation. BCVA, intraocular pressure, corneal astigmatism, and corneal endothelial cell count in the two groups before and after operation were compared. Results: BCVA after operation in the two groups was significantly elevated, while the corneal endothelial cell count was significantly reduced, but the comparison of BCVA and corneal endothelial cell count between the two groups was not statistically significant. The intraocular pressure after operation in the two groups was elevated first and reduced later. The intraocular pressure 2 h and 1 d after operation was significantly elevated when compared with before operation. The intraocular pressure 2 d after operation was not significantly different from that before operation. The comparison of intraocular pressure at each timing point after operation between the two groups was not statistically significant. The corneal astigmatism after operation in the two groups was elevated first and reduced later. The

  14. Teste de esforço: alterações do segmento ST restritas à fase de recuperação

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    Oliveira Fº J. A.

    1999-01-01

    Full Text Available OBJETIVO: Determinar a incidência de doença coronária aterosclerótica (DCA e/ou isquemia miocárdica em pacientes (pt com alterações do segmento ST restritas à fase de recuperação (ASTRR do teste ergométrico. CASUÍSTICA E MÉTODO: Estudo retrospectivo em 19 pacientes não consecutivos com ASTRR, através da cinecoronariografia e/ou cintigrafia de esforço planar. Amostra de 18 homens, uma mulher, com idade de 58 ± 9 anos, 18 sintomáticos. RESULTADOS: ASTRR correspondem a segmentos ST infra-desnivelados de 1 a 4 mm da linha de base, com inversão da onda T durante a recuperação precoce (2pt, tardia (14 pt. Foi documentada DCA em 14 pt (nove submetidos à cirurgia de revascularização; miocardiopatia hipertensiva com coronárias normais em 3 pt e prolapso de válvula mitral em 1 pt. Em 13 casos a cinecoronariografia e/ou cintilografia de esforço foram realizados dentro de seis meses do Teste Ergométrico, sendo a presença de DCA e ou isquemia miocárdica detectadas em 8 pt. Em 3 pt, testes ergométricos sucessivos mostraram ASTRR reprodutíveis em dois casos. CONCLUSÃO: Os autores relatam a elevada prevalência de DCA e ou hipoperfusão transitória na cintigrafia de esforço em homens sintomáticos de meia idade com ASTRR no teste de esforço.

  15. ANÁLISE DA PRODUÇÃO CIENTÍFICA BRASILEIRA EM CONTABILIDADE VOLTADA PARA O SEGMENTO DE GESTÃO SOCIAL E AMBIENTAL

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    Pedro Ylunga Costa da Silva

    2013-06-01

    Full Text Available A pesquisa objetivou identificar as mudanças ocorridas na produção científica brasileira em contabilidade voltada para o segmento de Gestão Social e Ambiental, publicada em periódicos no nível Qualis A, B e C, nos últimos 20 anos. A fundamentação teórica aborda aspectos relacionados à responsabilidade social e ambiental, contabilidade ambiental, contabilidade social, instrumentos contábeis de evidenciação da responsabilidade social das empresas, os relatórios sociais de apoio à gestão ambiental entre outros aspectos ligados ao tema. A metodologia admitida caracteriza-se como sendo uma pesquisa descritiva, de natureza aplicada, com metodologia de uma pesquisa documental e com o método dedutivo. Utilizando para isso, o instrumento de análise com base nas seis dimensões definidas para o estudo, quais sejam: quantitativa, autoria, temática, metodologia, referencial teórico e cientificidade. A coleta de dados foi realizada no portal de cada um dos periódicos selecionados e por meio destes impressos, durante o ano de 2010. A conclusão indica que a contabilidade voltada para o segmento de gestão social e ambiental vem, nos últimos anos, dando largos passos para evoluir e atender as necessidades sociais, econômicas e financeiras da sociedade; e que é preciso avançar um pouco mais no rigor metodológico utilizado nos trabalhos produzidos.

  16. Trajetórias tecnológicas no segmento offshore: ambiente e oportunidades Technological trajectories in the offshore segment: enviroment and opportunities

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    José Benedito Ortiz Neto

    2008-08-01

    Full Text Available Este artigo apresenta as diferentes trajetórias tecnológicas do segmento offshore na indústria petrolífera mundial considerando os seus principais aspectos e marcos constituintes. Mais especificamente, serão analisadas as trajetórias diferentes nas duas primeiras grandes províncias de petróleo do segmento offshore: o Golfo do México (EUA e o Mar do Norte (Europa. Junto com a Bacia de Campos (Brasil, são as mais produtivas e ricas do planeta e onde as três trajetórias tecnológicas foram desenvolvidas. Esse levantamento histórico é importante porque resgata os elementos que dão as bases do conhecimento tecnológico que permitiu à Petrobras, de forma inédita, iniciar as suas atividades offshore nas décadas de 1960-1970. Será visto aqui que a exploração offshore significou o surgimento de um novo paradigma tecnológico sustentado por três trajetórias.This article presents different technological trajectories concerning the offshore exploration segment in the world petroleum industry, considering their main aspects and components. More specifically, different trajectories will be analyzed in the first two largest crude oil territories: Gulf of Mexico (USA and Sea North (Europe. These, along with Bacia de Campos in Brazil, are the most productive and the richest regions in the planet and, therefore, where the three technological trajectories have been developed. This historic survey is important because it reveals the elements that provide the basis for technological knowledge, which allowed Petrobras to start its offshore activities in the 60s and 70s, via an original technology. The offshore exploration meant the emergence of a new technological paradigm supported by three trajectories.

  17. Intraocular robotic interventional surgical system (IRISS): Mechanical design, evaluation, and master-slave manipulation.

    Science.gov (United States)

    Wilson, Jason T; Gerber, Matthew J; Prince, Stephen W; Chen, Cheng-Wei; Schwartz, Steven D; Hubschman, Jean-Pierre; Tsao, Tsu-Chin

    2018-02-01

    Since the advent of robotic-assisted surgery, the value of using robotic systems to assist in surgical procedures has been repeatedly demonstrated. However, existing technologies are unable to perform complete, multi-step procedures from start to finish. Many intraocular surgical steps continue to be manually performed. An intraocular robotic interventional surgical system (IRISS) capable of performing various intraocular surgical procedures was designed, fabricated, and evaluated. Methods were developed to evaluate the performance of the remote centers of motion (RCMs) using a stereo-camera setup and to assess the accuracy and precision of positioning the tool tip using an optical coherence tomography (OCT) system. The IRISS can simultaneously manipulate multiple surgical instruments, change between mounted tools using an onboard tool-change mechanism, and visualize the otherwise invisible RCMs to facilitate alignment of the RCM to the surgical incision. The accuracy of positioning the tool tip was measured to be 0.205±0.003 mm. The IRISS was evaluated by trained surgeons in a remote surgical theatre using post-mortem pig eyes and shown to be effective in completing many key steps in a variety of intraocular surgical procedures as well as being capable of performing an entire cataract extraction from start to finish. The IRISS represents a necessary step towards fully automated intraocular surgery and demonstrated accurate and precise master-slave manipulation for cataract removal and-through visual feedback-retinal vein cannulation. Copyright © 2017 John Wiley & Sons, Ltd.

  18. Electrochemical lysis at the stage of endoresection for large posterior intraocular tumors

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    Yu. A. Belyy

    2012-01-01

    Full Text Available Purpose: to design the new combined technique of endoresection with intraoperative intraocular electrochemical lysis at the tumor destruction stage for large posterior intraocular tumors.Methods: 3 patients (3 eyes with large choroidal melanomas t3N0M0 (tumor thickness — 8-10 mm, base diameter — 13-15 mm, juxtapapillary localization. Mean age was 55.4 years old. Endoresection with intraoperational intraocular electrochemical lysis of the tumor was performed. Electrochemical lysis was performed with use of the technical unit ECU 300 (Soering, Germany and the original method of combined intratumoral positioning of two platinum electrodes: anode and cathode.Results: the tumor was removal completely in all 3 cases. the anatomical retinal reattachment was reached in all patients. Sclera was safe in all 3 cases. Visual acuity was not changed (NLP. At the place of the removal tumor a surgical choroidal coloboma without pigmentation all over scleral bed and periphery was shown in all cases in distant postoperative period (from 1.5 to 3 years. No local recurrences or metastasis were revealed in all patients.Conclusion: Further investigations in clinical group are necessarily to determinate the real possibilities of the combined method and the indications for endoresection with intraoperative intraocular electrochemical lysis for large intraocular tumors. 

  19. Uso dos Atributos da Contabilidade Gerencial Propostos por Moores e Yuen (2001 em Empresas de um Segmento Industrial de Santa CatarinaUse of the Management Accounting Attributes Proposed by Moores and Yuen (2001 in Companies of an Industry in de State of Santa CatarinaUso de los Atributos de la Contabilidad de Gestión Propuestos por Yuen y Moores (2001 en Empresas de un Segmento de la Industria de Santa Catarina

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    BEUREN, Ilse Maria

    2012-12-01

    Full Text Available RESUMOO sistema de contabilidade gerencial deve prover os gestores de informações para o cumprimento de objetivos e metas da organização, adaptadas à realidade e estratégias organizacionais. O estudo objetiva averiguar o uso dos atributos da contabilidade gerencial, conforme proposto por Moores e Yuen (2001, nas empresas do segmento industrial de máquinas, aparelhos e materiais elétricos do Estado de Santa Catarina. Pesquisa descritiva realizou-se por meio de levantamento com aplicação de questionário aos gestores das empresas, cujas questões foram adaptadas de Necyk (2008, fundamentadas na proposição de Moores e Yuen (2001. A população compreende as 264 empresas listadas na Secretaria da Fazenda do Estado de Santa Catarina do referido segmento de atividade econômica, e a amostra não aleatória constitui-se das 40 que responderam à pesquisa. Os resultados mostram que os atributos da contabilidade gerencial propostos por Moores e Yuen (2001 em suas duas vertentes são utilizados nas empresas. O atributo seleção de informações, que aborda as fontes de informações utilizadas, obteve concordância de 57%. O atributo apresentação de informações, que aborda formato, tipo e disponibilidade das informações, obteve concordância de 64%. Conclui-se que as empresas participantes da pesquisa utilizam tipos de informações diversificados em maior proporção do que as fontes de informações, ainda que várias dessas informações não estejam sendo apresentadas no formato adequado, podendo prejudicar sua relevância na tomada de decisões.ABSTRACTThe management accounting system should provide to managers the information required to accomplish goals and objectives of the organization, adapted to reality and organizational strategies. The goal of this study is to investigate the use of the management accounting attributes, as proposed by Moores and Yuen (2001, in companies operating in the machinery, electrical equipment and

  20. Lens parameters as predictors of intraocular pressure changes after phacoemulsification.

    Science.gov (United States)

    Moghimi, S; Abdi, F; Latifi, G; Fakhraie, G; Ramezani, F; He, M; Lin, S C

    2015-11-01

    To evaluate intraocular pressure (IOP) change after cataract surgery in non-glaucomatous eyes with narrow and open angles (OAs) and its relation to novel lens parameters measured by anterior segment optical coherence tomography (AS-OCT). University affiliated hospital, Farabi Eye Hospital, Tehran, Iran. Prospective interventional case series. In this prospective study, 85 non-glaucomatous eyes underwent phacoemulsification and lens implantation. Thirty-nine eyes had OAs and 46 eyes had narrow angles (NAs). IOP and biometric parameters were measured by AS-OCT preoperatively and 3 months after surgery. Change in IOP and its relation to biometric parameters, including lens vault (LV), anterior vault (AV), defined as the sum of the LV and the ACD, and relative LV (rLV), defined as the ratio of the LV to the AV, were evaluated. The main outcome measure was degree of IOP change after phacoemulsification. Of the 85 patients included in the analysis, 35 were male and 50 were female with an overall mean age of 62.2 ± 8.9 years. The average IOP reduction was -4.95 ± 2.26 mm Hg, from a preoperative mean of 17.12 ± 2.47 mm Hg, at 3 months after cataract surgery. The amount of IOP reduction was significantly greater in the NA compared with the OA group. In multivariate linear regression analysis, preoperative IOP and AV were significantly associated with IOP decrease (all ≤ 0.03). Cataract surgery results in IOP reduction in both OA and NA eyes. The amount of IOP reduction is related to AV.

  1. Intraocular and crystalline lens protection from ultraviolet damage.

    Science.gov (United States)

    Sliney, David H

    2011-07-01

    Although the risks of excess solar ultraviolet (UV) exposure of the skin are well recognized, the need for eye protection is frequently overlooked, or when sunglasses are also recommended, specific guidance is wrong or is not explained. Guidance from the World Health Organization at its InterSun webpage advises people to wear "wrap-around" sunglasses under many conditions. The objective of this study was to examine the need for UV filtration in prescription lenses, contact lenses, and sunglasses. The geometry of UV exposure of both eyes, solar position, ground reflection, pupil size, and lid opening were studied. Because an accurate determination of cumulative ocular exposure is difficult, the cornea itself can serve as a biologic dosimeter, because photokeratitis is not experienced on a daily basis but does under certain ground-surface and sunlight conditions. From a knowledge of the UV-threshold dose required to produce photokeratitis, we have an upper level of routine ocular exposure to ambient UV. From ambient UV measurements and observed photokeratitis, the upper limits of UV exposure of the crystalline lens or an intraocular lens implant are estimated. The risk of excess UV exposure of the germinative cells of the lens is greatest from the side. Sunglasses can actually increase UV exposure of the germinative region of the crystalline lens and the corneal limbus by disabling the eyes' natural protective mechanisms of lid closure and pupil constriction! The level of UV-A risk is difficult to define. Proper UV-absorbing contact lenses offer the best mode for filtering needless exposure of UV radiation of the lens and limbus.

  2. Blood pressure modifies retinal susceptibility to intraocular pressure elevation.

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    Zheng He

    Full Text Available Primary open angle glaucoma affects more than 67 million people. Elevated intraocular pressure (IOP is a risk factor for glaucoma and may reduce nutrient availability by decreasing ocular perfusion pressure (OPP. An interaction between arterial blood pressure and IOP determines OPP; but the exact contribution that these factors have for retinal function is not fully understood. Here we sought to determine how acute modifications of arterial pressure will affect the susceptibility of neuronal function and blood flow to IOP challenge. Anaesthetized (ketamine:xylazine Long-Evan rats with low (∼60 mmHg, sodium nitroprusside infusion, moderate (∼100 mmHg, saline, or high levels (∼160 mmHg, angiotensin II of mean arterial pressure (MAP, n = 5-10 per group were subjected to IOP challenge (10-120 mmHg, 5 mmHg steps every 3 minutes. Electroretinograms were measured at each IOP step to assess bipolar cell (b-wave and inner retinal function (scotopic threshold response or STR. Ocular blood flow was measured using laser-Doppler flowmetry in groups with similar MAP level and the same IOP challenge protocol. Both b-wave and STR amplitudes decreased with IOP elevation. Retinal function was less susceptible to IOP challenge when MAP was high, whereas the converse was true for low MAP. Consistent with the effects on retinal function, higher IOP was needed to attenuated ocular blood flow in animals with higher MAP. The susceptibility of retinal function to IOP challenge can be ameliorated by acute high BP, and exacerbated by low BP. This is partially mediated by modifications in ocular blood flow.

  3. Risk factors for intraocular pressure rise following phacoemulsification

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    Muge Coban-Karatas

    2013-01-01

    Full Text Available Purpose: This study was designed to analyze the risk factors resulting in high intraocular pressure (IOP, which was accepted as IOP higher than 22 mmHg, following uncomplicated phacoemulsification. Materials and Methods: The records of 812 eyes of 584 patients who underwent uncomplicated phacoemulsification were evaluated. There were 330 men and 254 women ranging between the age of 26 and 89 years (65.4 ± 9.8 years. The preoperative, postoperative first day (day 1, first week (day 7, and first month (day 30 IOP values were analyzed. Data on history of diabetes, glaucoma, pseudoexfoliation (PXF, incision site, capsular staining with trypan blue, and surgeon were recorded. A multinomial regression analysis was performed to analyse the relationship of the factors with postoperative high IOP. Results: The mean IOP was 15.6 ± 4.3 mmHg preoperatively. Postoperatively that were changed to 19.7 ± 9.0 mmHg at day 1, 12.7 ± 4.5 mmHg at day 7, and 12.8 ± 3.7 mmHg at day 30. The factors such as surgeon, presence of PXF, diabetes, surgical incision site, and trypan blue were not related to the postoperative high IOP (P > 0.05, in all. The only factor that related to high IOP at all visits was glaucoma (P < 0.005. Conclusion: According to our results, preoperative diagnosis of glaucoma seems to be the only factor to affect the postoperative IOP higher than 22 mmHg.

  4. Effect of music on surgical skill during simulated intraocular surgery.

    Science.gov (United States)

    Kyrillos, Ralph; Caissie, Mathieu

    2017-12-01

    To evaluate the effect of Mozart music compared to silence on anterior segment surgical skill in the context of simulated intraocular surgery. Prospective stratified and randomized noninferiority trial. Fourteen ophthalmologists and 12 residents in ophthalmology. All participants were asked to perform 4 sets of predetermined tasks on the EyeSI surgical simulator (VRmagic, Mannheim, Germany). The participants completed 1 Capsulorhexis task and 1 Anti-Tremor task during 3 separate visits. The first 2 sets determined the basic level on day 1. Then, the participants were stratified by surgical experience and randomized to be exposed to music (Mozart sonata for 2 pianos in D-K448) during either the third or the fourth set of tasks (day 2 or 3). Surgical skill was evaluated using the parameters recorded by the simulator such as "Total score" and "Time" for both tasks and task-specific parameters such as "Out of tolerance percentage" for the Anti-Tremor task and "Deviation of rhexis radius from 2.5 mm," "Roundness," and "Centering" for the Capsulorhexis task. The data were analyzed using the Wilcoxon signed-rank test. No statistically significant differences were noted between exposure and nonexposure for all the Anti-Tremor task parameters as well as most parameters for the Capsulorhexis task. Two parameters for the Capsulorhexis task showed a strong trend for improvement with exposure to music ("Total score" +23.3%, p = 0.025; "Roundness" +33.0%, p = 0.037). Exposure to music did not negatively impact surgical skills. Moreover, a trend for improvement was shown while listening to Mozart music. Copyright © 2017 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.

  5. Flanged Intrascleral Intraocular Lens Fixation with Double-Needle Technique.

    Science.gov (United States)

    Yamane, Shin; Sato, Shimpei; Maruyama-Inoue, Maiko; Kadonosono, Kazuaki

    2017-08-01

    To report the clinical outcomes of a new technique for transconjunctival intrascleral fixation of an intraocular lens (IOL). Prospective, noncomparative, interventional case series. One hundred eyes of 97 consecutive patients with aphakia, dislocated IOL, or subluxated crystalline lens who underwent posterior chamber sutureless implantation of an IOL were studied. Two angled incisions parallel to the limbus were made by 30-gauge thin-wall needles. Haptics of an IOL were externalized with the needles and cauterized to make a flange of the haptics. The flange of the haptics were pushed back and fixed into the scleral tunnels. Best-corrected visual acuity (VA), corneal endothelial cell density, IOL tilt, and complications were determined. The IOLs were fixed with exact centration and axial stability. The mean preoperative best-corrected VA was 0.25 logarithm of the minimum angle of resolution (logMAR) units; after surgery, it improved significantly to 0.11 logMAR, 0.09 logMAR, 0.12 logMAR, and 0.04 logMAR at 6, 12, 24, and 36 months, respectively (P IOL tilt was 3.4°±2.5°. The postoperative complications included iris capture by the IOL in 8 eyes (8%), vitreous hemorrhage in 5 eyes (5%), and cystoid macular edema in 1 eye (1%). There were no incidents of postoperative retinal detachment, endophthalmitis, or IOL dislocation. We have developed a new technique for intrascleral IOL fixation. The flanged IOL fixation technique is a simple and minimally invasive method for achieving good IOL fixation with firm haptic fixation. Copyright © 2017 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  6. Early versus late traumatic cataract surgery and intraocular lens implantation.

    Science.gov (United States)

    Tabatabaei, S A; Rajabi, M B; Tabatabaei, S M; Soleimani, M; Rahimi, F; Yaseri, M

    2017-08-01

    PurposeTo determine the proper time for traumatic cataract surgery after open globe injuries.SettingFarabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.DesignRandomized clinical trial.Patients and methodsIn a randomized clinical trial, 30 eyes with traumatic cataract after open globe injury with IOL implantation underwent early (in the first week after the trauma) and 30 eyes underwent late cataract surgery (from the first to second month after the trauma). We excluded patients who were under 12-year-old. All patients were visited at 1 week, 4 weeks, 12 weeks, and 6 months after surgery. In each visit, patients were examined regarding visual acuity, intraocular pressure (IOP), anterior chamber inflammation, IOL position, and posterior synechiae. In addition, posterior segment evaluation and fundoscopy were performed. Intraoperative complication including posterior capsular rupture, anterior vitrectomy, and zonulysis as well as the site of IOL implantation were documented and post-operative complications including raised IOP, anterior chamber inflammation, visual axis opacity, posterior synechiae, subluxation of IOL, and IOL pigment deposition were listed.ResultsBest-corrected visual acuity 6 months after surgery was not different between the two groups. Also in early cataract surgery group, the rate of posterior capsular rupture was not significantly higher than the late surgery group (P=0.069). On the other hand, zonulysis was significantly higher in the late procedure group (P=0.039). Other complications including anterior vitrectomy, raised IOP, anterior chamber inflammation, visual axis opacity, posterior synechiae, subluxation of IOL, and IOL pigment deposition were not different in the two groups.ConclusionsEarly and late traumatic cataract surgery and IOL implantation after open globe injuries, have no significant difference regarding the post-surgical BCVA and prominent intraoperative and post-operative complications.

  7. Glued intrascleral fixation of posterior chamber intraocular lens in children.

    Science.gov (United States)

    Kumar, Dhivya Ashok; Agarwal, Amar; Prakash, Dimple; Prakash, Gaurav; Jacob, Soosan; Agarwal, Athiya

    2012-04-01

    To evaluate the short-term results of glued intrascleral fixation of posterior chamber intraocular lens (glued IOL) in children without adequate capsular support. Noncomparative retrospective observational case series. Institutional practice. Forty-one eyes of 33 children who underwent glued IOL implantation were retrospectively evaluated. The indications were postsurgical aphakia, subluxated cataract, ectopia lentis, traumatic subluxation, and decentered IOL. Visual acuity (VA), endothelial cell changes, intraoperative and postoperative complications. The mean age at the time of glued IOL was 10.7±3.6 years (range 5-15). The mean duration of follow-up after surgery was 17.5±8.5 months (range 12-36). The mean postoperative best spectacle-corrected visual acuity (BCVA in decimal equivalent) was 0.43±0.33 and there was significant change noted (P20/60 BCVA was obtained in 17.1% and 46.3% of eyes respectively. BCVA improvement more than 1 line was seen in 22 eyes (53.6%). The mean postoperative refraction was myopic (-1.19±0.7 diopters [D]) in 19 eyes and hyperopic (+1.02±0.7 D) in 22 eyes. The mean endothelial loss was 4.13% (range 1.3%-5.94%). The 3 causes of reduced BCVA were the preexisting corneal, retinal pathology, and amblyopia. Postoperative complications included optic capture in 1 eye (2.4%), macular edema in 2 eyes (4.8%), and clinical decentration in 2 eyes (4.8%). There was no postoperative retinal detachment, IOL dislocation, endophthalmitis, or glaucoma. Short-term results in children after glued IOL were favorable, with a low rate of complications. However, regular follow-ups are required since long-term risks are unknown. Copyright © 2012 Elsevier Inc. All rights reserved.

  8. Effect of Hydrogen Sulfide Donors on Intraocular Pressure in Rabbits.

    Science.gov (United States)

    Salvi, Ankita; Bankhele, Pratik; Jamil, Jamal; Chitnis, Madhura Kulkarni; Njie-Mbye, Ya Fatou; Ohia, Sunny E; Opere, Catherine A

    2016-01-01

    In this study, we investigated the effect of a slow-releasing hydrogen sulfide (H2S) donor, GYY 4137, on intraocular pressure (IOP) in normotensive rabbits. Furthermore, we compared the IOP-lowering action of GYY 4137 with those elicited by other H2S-producing compounds, l-cysteine and ACS67 (a hybrid compound of latanoprost with an H2S-releasing moiety). IOP was measured in New Zealand normotensive male albino rabbits using a pneumatonometer (model 30 classic; Reichert Ophthalmic Instruments, Depew, NY). At 0 h, 50 μL of test compounds were applied topically to 1 eye of each animal, while the contralateral eye received the same quantity of vehicle (saline). IOP was measured hourly until baseline IOP readings were attained and animal eyes monitored for potential side effects (i.e., tearing, hyperemia). GYY 4137 (0.1%-2%) produced a dose-dependent decrease in IOP reaching a maximum of 27.8% ± 3.14% (n = 5) after 6 h. Interestingly, a significant contralateral effect was observed in vehicle-treated controls eyes at all doses tested. l-cysteine (5%) and ACS67 (0.005%) also elicited a significant (P vehicle-treated control eyes. We conclude that GYY 4137 and other H2S-producing donors can reduce IOP in normotensive rabbits. However, the profile of IOP-lowering action of GYY 4137 was different from the other H2S donors affirming its ability to act as a slow-releasing gas donor.

  9. Driving time modulates accommodative response and intraocular pressure.

    Science.gov (United States)

    Vera, Jesús; Diaz-Piedra, Carolina; Jiménez, Raimundo; Morales, José M; Catena, Andrés; Cardenas, David; Di Stasi, Leandro L

    2016-10-01

    Driving is a task mainly reliant on the visual system. Most of the time, while driving, our eyes are constantly focusing and refocusing between the road and the dashboard or near and far traffic. Thus, prolonged driving time should produce visual fatigue. Here, for the first time, we investigated the effects of driving time, a common inducer of driver fatigue, on two ocular parameters: the accommodative response (AR) and the intraocular pressure (IOP). A pre/post-test design has been used to assess the impact of driving time on both indices. Twelve participants (out of 17 recruited) completed the study (5 women, 24.42±2.84years old). The participants were healthy and active drivers with no visual impairment or pathology. They drove for 2h in a virtual driving environment. We assessed AR and IOP before and after the driving session, and also collected subjective measures of arousal and fatigue. We found that IOP and AR decreased (i.e., the accommodative lag increased) after the driving session (p=0.03 and p<0.001, respectively). Moreover, the nearest distances tested (20cm, 25cm, and 33cm) induced the highest decreases in AR (corrected p-values<0.05). Consistent with these findings, the subjective levels of arousal decreased and levels of fatigue increased after the driving session (all p-values<0.001). These results represent an innovative step towards an objective, valid, and reliable assessment of fatigue-impaired driving based on visual fatigue signs. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Photochemical generation of antimicrobial Ag-nanoparticles in intraocular lenses

    Science.gov (United States)

    Badur, Thorben; Kim, Hee-Cheol; Hampp, Norbert

    2017-02-01

    The antimicrobial properties of silver (Ag) nanoparticles (NP) have been investigated in depth during the last decades.[1] For cataract treatment minimal invasive surgery has become state-of-the-art. The physicians are still fighting against postoperative inflammations, such as endophthalmitis.[2] We present a novel approach to reduce these postoperative complications by equipping the hydrophilic intraocular lenses (IOL) with a Ag NP depot. As the Ag NP are completely entrapped inside the polymeric IOL no direct contact of the nanoparticles with epithelial cells may occur. Using 1-hydroxybenzotriazole (HOBt) or 7-hydroxycumarine (7HOCum) as photo reduction mediators (PRM) the formation of the Ag NP is accomplished in situ. PRM and Ag nitrate are diffused into the ready made IOL. By means of two-photon-absorption (TPA) photochemistry at λTPA = 532 nm the Ag NP generation is precisely controlled to occur inside the IOL only. At no point NP are directly exposed to the surface.[3] Interesting dependencies between the used PRM and the resulting particle size distribution or the effectiveness of the silver ion reduction inside the polymer matrix are reported. The Ag NP were prepared in the outer area of the IOL not to affect the optical properties of the ophthalmic implant. The amount of Ag ions released was determined and found to be sufficient to effectively reduce the counts of airborne germs. Besides HOBt and 7HOCum we also investigated the photo reductive properties of several other organic reagents, such as benzophenone (BP) and 4-hydroxybenzophenone (4HOBP) for the ability to produce even three-dimensional nanoparticle structures inside a polymer matrix.

  11. Reconstrucción de Piso Orbitario con esclera en Fracturas del Tercio Medio. Presentación de caso

    OpenAIRE

    Alexis A. Amador-Velázquez; Martha Rodríguez-Milord; Reynaldo Oro-Canelles

    2011-01-01

    Presentó un caso el cual fue víctima de una agresión con un objeto cortante que le produjo una fractura compleja del tercio medio facial provocándole una Fractura Le Fort III unilateral izquierda y Le Fort II unilateral derecha con herida perforante y extensa en globo ocular izquierdo que fue necesario realizar su eviseración, extrayendo de este un fragmento de esclera del segmento anterior de mas menos 1cm de largo para reparar una fractura mediana en piso orbital derecho logrando su fijaci...

  12. Preferencias de leche fresca de bovino del consumidor de Baja California, Mexico

    Directory of Open Access Journals (Sweden)

    Iliana Enriqueta Montaño Méndez

    2013-01-01

    Full Text Available El documento tiene como objetivo conocer las preferencias del consumidor de Baja California por leche de bovino y sus hábitos de consumo, así como identificar segmentos para el consumo de leche a partir de los principales atributos como presentación, tipo de grasa y precio, e identificar nichos de mercado para nuevos productos. Para determinar las preferencias del consumidor, se utilizaron técnicas del análisis de conjunto, análisis de segmentación y análisis de simulación. Para lo anterior, se diseñó y aplicó un cuestionario a una muestra representativa conformada por 418 consumidores del Estado, para conocer el producto ideal y caracterizar al consumidor bajo diferentes segmentaciones basados en sus preferencias. Los resultados muestran mayor preferencia por leche pasteurizada con tipo de grasa entera, a la cual le atribuyen mejor sabor, seguida por la leche ultra pasteurizada y las fórmulas lácteas. Además se encontró un segmento de mercado para nuevos productos y la valoración positiva al precio situación no habitual dentro de los consumidores agroalimentarios.

  13. Clinical assessment of diclofenac sodium eye drops in toric intraocular lens implantation

    Directory of Open Access Journals (Sweden)

    Yan Luo

    2013-05-01

    Full Text Available AIM:To evaluate the application of diclofenac sodium eye drops in toric intraocular lens implantation. METHODS: From January 2011 to February 2012, 38 eyes of 37 patients, who underwent toric intraocular lens implantation in this hospital, were randomly divided into diclofenac sodium eye drops group(trial groupand control group. Patient's degree of cooperation during surgery and inflammation postoperation after 1 day, 3,7, days, 1 month and 3 months were evaluated. RESULTS: Patient's degree of cooperation during surgery in the trial group(1.53±0.62was significantly better than in the control group(2.40±0.88, P<0.05. Inflammation reaction was gentle in the trial group 1 day postoperatively. CONCLUSION: Diclofenac sodium eye drops used during toric intraocular lens implantation can obviously alleviate eye irritation, and increase the cooperation of patients.

  14. Intraocular Pressure Increases After Intraarticular Knee Injection With Triamcinolone but Not Hyaluronic Acid.

    Science.gov (United States)

    Taliaferro, Kevin; Crawford, Alexander; Jabara, Justin; Lynch, Jonathan; Jung, Edward; Zvirbulis, Raimonds; Banka, Trevor

    2018-03-09

    Intraarticular steroid injections are a common first-line therapy for severe osteoarthritis, which affects an estimated 27 million people in the United States. Although topical, oral, intranasal, and inhalational steroids are known to increase intraocular pressure in some patients, the effect of intraarticular steroid injections on intraocular pressure has not been investigated, to the best of our knowledge. If elevated intraocular pressure is sustained for long periods of time or is of sufficient magnitude acutely, permanent loss of the visual field can occur. How does intraocular pressure change 1 week after an intraarticular knee injection either with triamcinolone acetonide or hyaluronic acid? A nonrandomized, nonblinded prospective cohort study was conducted at an outpatient, ambulatory orthopaedic clinic. This study compared intraocular pressure elevation before and 1 week after intraarticular knee injection of triamcinolone acetonide versus hyaluronic acid for management of primary osteoarthritis of the knee. Patients self-selected to be injected in their knee with either triamcinolone acetonide or hyaluronic acid before being informed of the study. The primary endpoint was intraocular pressure elevation of ≥ 7 mm Hg 1 week after injection. This cutoff is determined as the minimum significant pressure change in the ophthalmology literature recognized as an intermediate responder to steroids. Intraocular pressure was measured using a handheld Tono-Pen® applanation device. This device is frequently used in intraocular pressure measurement in clinical and research settings; 10 sequential measurements are obtained and averaged with a confidence interval. Only measurements with a 95% confidence interval were used. Over a 6-month period, a total of 96 patients were approached to enroll in the study. Sixty-two patients out of 96 approached (65%) agreed. Thirty-one (50%) were injected with triamcinolone and 31 (50%) were injected with hyaluronic acid. Patients

  15. The phakic intraocular lens implant: in-depth focus on posterior chamber phakic IOLs.

    Science.gov (United States)

    Zaldivar, R; Ricur, G; Oscherow, S

    2000-02-01

    Phakic Intraocular surgery has come a long way in the past 20 years, especially in the evolution of posterior chamber phakic intraocular lenses (PC PIOLs). Clinical trials worldwide are showing acceptable results concerning efficacy, predictability, stability, and safety. PC PIOLS are proving to be a promising option for patients with high and extreme ametropia who cannot benefit from conventional corneal refractive procedures. This article provides an in-depth examination of PC PIOLs, their origin and evolution, and the results of past and current clinical studies. Reports of historical importance and studies published since the 1990s in peer-reviewed journals, textbooks, and monthly eye magazines, as well as Food and Drug Administration preliminary clinical findings, are reviewed. Anterior chamber phakic intraocular lenses are mentioned briefly.

  16. Changes of intraocular pressure in different trimesters of pregnancy among Syrian refugees in Turkey: A cross-sectional study.

    Science.gov (United States)

    Tolunay, Harun Egemen; Özcan, Sait Coşkun; Şükür, Yavuz Emre; Özarslan Özcan, Deniz; Adıbelli, Fatih Mehmet; Hilali, Neşe Gül

    2016-06-01

    To evaluate the physiologic changes in intraocular pressure associated with pregnancy in healthy Syrian refugee women in Turkey. In this cross-sectional study, intraocular pressures were measured using a Goldmann tonometer in 235 patients in the first, second, and third trimester of pregnancy and puerperium among Syrian refugees in Turkey. Mean intraocular pressures values of the right eye were 15.5±2.5 mmHg, 14.4±1.4 mmHg, 13.9±1.6 and 14.7±1.9 mmHg in the three trimesters and puerperium, respectively. Mean intraocular pressures values of the left eye were 15.3±1.6 mmHg, 14.3±1.4 mmHg, 13.9±1.6 and 15.3±2.2 mmHg in the three trimesters and puerperium, respectively. The mean intraocular pressures values measured from both eyes were significantly higher in first trimester and puerperal period than in the third trimester (p<0.001). Changes in the intraocular pressure in pregnancy are common and temporary. This study shows the baseline changes in the intraocular pressure during pregnancy in healthy women. Therefore, we cannot extrapolate the results to the whole eye. A decrease in intraocular pressures was shown in healthy pregnant women.

  17. Correlation between Central Corneal Thickness and Intraocular Pressure Measured by Goldmann Applanation Tonometry or Pascal Dynamic Contour Tonometry.

    Science.gov (United States)

    Katsimpris, J M; Theoulakis, P E; Vasilopoulos, K; Skourtis, G; Papadopoulos, G E; Petropoulos, I K

    2015-04-01

    The aim of this study was to investigate the relationship between central corneal thickness and intraocular pressure measured by Goldmann applanation tonometry and Pascal dynamic contour tonometry. The study included 45 persons (90 eyes), divided into 4 groups: a) 10 normal volunteers (20 eyes); b) 16 patients (32 eyes) with primary open-angle glaucoma; c) 8 patients (16 eyes) with normal-tension glaucoma; and d) 11 patients (22 eyes) with ocular hypertension. Intraocular pressure was measured by Goldmann applanation tonometry and Pascal dynamic contour tonometry, and central corneal thickness was measured by ultrasound pachymetry. The relationship between intraocular pressure and central corneal thickness was evaluated. Intraocular pressure was correlated positively but not strongly enough with central corneal thickness when it was measured by Goldmann applanation tonometry. On the contrary, there was no correlation between intraocular pressure and central corneal thickness when intraocular pressure was measured by Pascal dynamic contour tonometry. Central corneal thickness is an important variable in the evaluation of intraocular pressure by Goldmann applanation tonometry. This factor does not interfere with the intraocular pressure measurements taken by Pascal dynamic contour tonometry. Georg Thieme Verlag KG Stuttgart · New York.

  18. [Association between two different types of strangling and intraocular pressure variation in jiu-jitsu athletes].

    Science.gov (United States)

    Scarpi, Marinho Jorge; Conte, Marcelo; Rossin, Reginaldo Alexandre; Skubs, Renato; Lenk, Rudolf Eberhard; Brant, Rodrigo

    2009-01-01

    To verify the association between two different types of strangling with intraocular pressure variation in jiu-jitsu athletes. An observational study was performed on 9 athletes of jiu-jitsu, with at least 6 month of training, male, aged 20 to 30 years, without any physical and eyeball lesions. Associations between intraocular pressure and Cross Choke from the guard strangling (E1), and E2 - Cross Choke from mount strangling were gotten. Intraocular pressure was determined by using Perkins tonometer, at first in the absence of physical exercise over the last 24 hours and after each strangling. Then it was carried out the intraocular pressure measure at each 3 minutes, during 12 minutes of exercise recovery (R1, R2, R3, and R4) keeping the athletes lied down. Statistical analysis was done using ANOVA test and Bonferroni post-test. Meaningful reduction of both eyes intraocular pressure occurred at the E2 situation comparing to the E1 situation at all exercise recovery measures: R1 (OD: 8.22 +/- 1.39 vs.11.33 +/- 2.00 / OE: 8.55 +/- 1.23 vs. 11.88 +/- 1.90), R2 (OD: 8.44 +/- 1.87 vs.10.22 +/- 2.53 / OE: 9.00 +/- 1.80 vs. 10.44 +/- 2.35), R3 (OD: 8.44 +/- 1.74 vs.9.78 +/- 2.54 / OE: 8.55 +/- 1.42 vs. 10.33 +/- 1.93) all with pjiu-jitsu strangling exercises, with intraocular pressure reduction.

  19. A study of patient satisfaction after cataract surgery with implantation of different types of intraocular lenses

    Directory of Open Access Journals (Sweden)

    Wei Ching-Kuo

    2012-10-01

    Full Text Available Abstract Background The implementation of capitated payment has driven medical institutions through developing balance billing for medical services. By exploring the patients’ decision-making factors on different self-pay items, a reference for the pricing and sales strategy for the related products can be formed. The major purposes of this study were to analyze the determinants of preoperative selection and postoperative satisfaction with implantation of different types of intraocular lenses in cataract surgery. Methods This cross-sectional study consisted of 127 patients that were 50 years of age and older, and who had phacoemulsification with intraocular lens implantation in both eyes. Data were collected by using a structured questionnaire. The following parameters were measured: access to medical care, attitude towards receiving medical products at one’s own expense, overall patient satisfaction and postoperative visual clarity. Results The results showed that the patient’s gender, educational level and economic status influenced the type of intraocular lens chosen. Patients in the insurance group cared about access to medical care, and patients in the balance billing group cared about product differentiation. ANOVA results showed no statistically significant differences in the overall satisfaction of the patients among the groups with different types of intraocular lenses. Patients that received cataract surgery with implantation of multifocal intraocular lenses had better vision when trying to view smaller objects and when looking at objects under strong light. Conclusions Manufacturers should increase the number of differences between their products, and health care providers can then recommend the appropriate intraocular lens in accordance with the needs or demands of their patients, and also by keeping in mind the financial constraints of their patients.

  20. Influence of macular pigment optical density spatial distribution on intraocular scatter.

    Science.gov (United States)

    Putnam, Christopher M; Bland, Pauline J; Bassi, Carl J

    This study evaluated the summed measures of macular pigment optical density (MPOD) spatial distribution and their effects on intraocular scatter using a commercially available device (C-Quant, Oculus, USA). A customized heterochromatic flicker photometer (cHFP) device was used to measure MPOD spatial distribution across the central 16° using a 1° stimulus. MPOD was calculated as a discrete measure and summed measures across the central 1°, 3.3°, 10° and 16° diameters. Intraocular scatter was determined as a mean of 5 trials in which reliability and repeatability measures were met using the C-Quant. MPOD spatial distribution maps were constructed and the effects of both discrete and summed values on intraocular scatter were examined. Spatial mapping identified mean values for discrete MPOD [0.32 (s.d.=0.08)], MPOD summed across central 1° [0.37 (s.d.=0.11)], MPOD summed across central 3.3° [0.85 (s.d.=0.20)], MPOD summed across central 10° [1.60 (s.d.=0.35)] and MPOD summed across central 16° [1.78 (s.d.=0.39)]. Mean intraocular scatter was 0.83 (s.d.=0.16) log units. While there were consistent trends for an inverse relationship between MPOD and scatter, these relationships were not statistically significant. Correlations between the highest and lowest quartiles of MPOD within the central 1° were near significance. While there was an overall trend of decreased intraocular forward scatter with increased MPOD consistent with selective short wavelength visible light attenuation, neither discrete nor summed values of MPOD significantly influence intraocular scatter as measured by the C-Quant device. Published by Elsevier España, S.L.U.

  1. Role of interferon-γ and cytotoxic T lymphocytes in intraocular tumor rejection.

    Science.gov (United States)

    Ligocki, Ann J; Brown, Joseph R; Niederkorn, Jerry Y

    2016-05-01

    The eye is normally an immunosuppressive environment. This condition is better known as immune privilege and protects the eye from immune-mediated inflammation of tissues that cannot regenerate. However, immune privilege creates a dilemma for the eye when intraocular neoplasms arise. In some cases, immune privilege is suspended, resulting in the immune rejection of intraocular tumors. This study employed a mouse model in which interferon-γ-dependent intraocular tumor rejection occurs. We tested the hypothesis that this rejection requires interferon-γ for the generation and functional capacity of cytotoxic T lymphocyte-mediated rejection of intraocular tumors. Tumors grew progressively in the eyes of interferon-γ knockout mice, even though the mice generated tumor-specific cytotoxic T lymphocyte responses in the periphery. However, interferon-γ knockout mice rejected tumors that were introduced into extraocular sites. Subcutaneous tumor immunization before intraocular challenge led to tumor rejection and preservation of the eye in wild-type mice. By contrast, tumors grew progressively in the eyes of interferon-γ knockout mice despite their ability to generate peripheral tumor-specific cytotoxic T lymphocytes as well as the capacity of CD8(+) T cells to enter the eye as shown by the presence of CD8 and perforin message and CD3(+)CD8(+) leukocytes within the tumor-bearing eye. We found that cytotoxic T lymphocytes generated in wild-type mice and adoptively transferred into interferon-γ knockout mice mediated the rejection of intraocular tumors in interferon-γ knockout hosts. The results indicate that interferon-γ is critical for the initial priming and differentiation of cytotoxic T lymphocytes residing in the periphery to produce the most effect antitumor function within the eye. © Society for Leukocyte Biology.

  2. The interaction between intracranial pressure, intraocular pressure and lamina cribrosal compression in glaucoma.

    Science.gov (United States)

    McMonnies, Charles W

    2016-05-01

    This review examines some of the biomechanical consequences associated with the opposing intraocular and intracranial forces. These forces compress the lamina cribrosa and are a potential source of glaucomatous pathology. A difference between them creates a displacement force on the lamina cribrosa. Increasing intraocular pressure and/or decreasing intracranial pressure will increase the trans-lamina cribrosa pressure difference and the risk of its posterior displacement, canal expansion and the formation of pathological cupping. Both intraocular pressure and intracranial pressure can be elevated during a Valsalva manoeuvre with associated increases in both anterior and posterior lamina cribrosa loading as well as its compression. Any resulting thinning of or damage to the lamina cribrosa and/or retinal ganglion cell axons and/or astrocyte and glial cells attached to the matrix of the lamina cribrosa and/or reduction in blood flow to the lamina cribrosa may contribute to glaucomatous neuropathy. Thinning of the lamina cribrosa reduces its stiffness and increases the risk of its posterior displacement. Optic nerve head posterior displacement warrants medical or surgical lowering of intraocular pressure; however, compared to intraocular pressure, the trans-lamina cribrosa pressure difference may be more important in pressure-related pathology of the optic nerve head region. Similarly important could be increased compression loading of the lamina cribrosa. Reducing participation in activities which elevate intraocular and intracranial pressure will decrease lamina cribrosa compression exposure and may contribute to glaucoma management and may have prognostic significance for glaucoma suspects. © 2016 The Authors. Clinical and Experimental Optometry © 2016 Optometry Australia.

  3. Comparison Between Mix-and-Match Implantation of Bifocal Intraocular Lenses and Bilateral Implantation of Trifocal Intraocular Lenses.

    Science.gov (United States)

    Bilbao-Calabuig, Rafael; González-López, Felix; Amparo, Ferrer; Alvarez, Gemma; Patel, Sunni R; Llovet-Osuna, Fernando

    2016-10-01

    To investigate the visual outcomes between mix-and-match bifocal intraocular lenses (IOLs) (ReSTOR +2.50 and +3.00 diopters [D]; Alcon Laboratories, Inc., Fort Worth, TX) versus bilateral implantation of a trifocal IOL (FineVision; PhysIOL, Liège, Belgium). Twenty-three patients (average age: 56.3 ± 6.9 years; range: 45 to 71 years) referred for lens phacoemulsification and IOL implantation were included in this study. Patients were randomly assigned to two groups. The FineVision group was bilaterally implanted with the FineVision trifocal IOL and the ReSTOR group was implanted with mix-and-match bifocal ReSTOR +2.50 and +3.00 D IOLs. A 3-month postoperative check was performed, and manifest refraction and logMAR uncorrected (UDVA) and corrected (CDVA) distance and near visual acuities were recorded. Monocular and binocular defocus curve testing was performed under photopic (85 cd/m 2 ) conditions in 0.50-D defocus steps. Contrast sensitivity was measured monocularly and binocularly under mesopic conditions at spatial frequencies of 3, 6, 12, and 18 cycles per degree using the CSV-1000 contrast test (VectorVision, Greenville, OH). There were no reported differences in monocular distance visual acuity or refractive outcomes between groups (P > .05). Furthermore, there were no significant differences in contrast sensitivity between the three IOLs (P > .05). The FineVision group achieved better monocular and binocular near and intermediate visual acuities under defocus curve testing than the ReSTOR group (P < .05). Binocular implantation of the FineVision trifocal IOL provided a better range of visual acuities at near and intermediate distances than mix-and-match bifocal IOL implantation. [J Refract Surg. 2016;32(10):659-663.]. Copyright 2016, SLACK Incorporated.

  4. Opacificação tipo "snowflake" em lente intra-ocular de polimetilmetacrilato (PMMA

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    Fabiana Dalla Rosa Pereira

    2011-04-01

    Full Text Available As lentes intraoculares têm sido utilizadas na reabilitação de pacientes submetidos à cirurgia de catarata desde 1959 com grande sucesso. Entretanto, alterações no biomaterial dessas lentes vêm sendo descritas nos últimos anos, diminuindo a acuidade visual dos pacientes anos depois da cirurgia. Este relato apresenta um caso de opacificação tipo "snowflake" em lente de polimetilmetacrilato, seguida de discussão sobre as principais características dessa alteração e indicação de retirada e troca da lente intraocular.

  5. Efecto de las prácticas agronómicas en las propiedades del suelo en laderas

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    Claro A. Alfonso

    2000-01-01

    Full Text Available Efecto de las prácticas agronómicas en las propiedades del suelo en laderas. En un suelo Ultisol de textura arenosa, fuertemente erosionado, de baja fertilidad en fósforo, materia orgánica y ácido, ubicado en la localidad de La Leña en la provincia de Pinar del Río, en la República de Cuba, se realizó durante el año 1996 un ensayo en dos segmentos de microcuencas, en las que se implementaron medidas de conservación de suelos consistentes en barreras vivas de Gliricidia sepium L. (primer segmento y Vetiveria zizanoide L. (segundo segmento complementadas con coberturas de maíz asociado con Mucuna d. y Canavalia e., como precedentes del frijol. Los resultados mostraron ligeros cambios de la pendiente intrabarreras con respecto al valor inicial (10 y 9%. Los valores de la biomasa seca total de las asociaciones fueron de 17 y 15 t/ha, la velocidad de cubrimiento a los 30 días fue mayor al 70%, la colonización radical profusa presentada por las asociaciones indican una mejora de la red poral del suelo, reflejándose en la tendencia positiva del estado interno de la estructura que evoluciona hacia un estado (G poroso. Los rendimientos de maíz fueron de 2900 y 2500 kg/ha y los de frijol de 1800 y 1630 kg/ha. Valores considerados elevados, si se tiene en cuenta el grado de deterioro de este suelo

  6. Comportamento motor, sob estímulo farmacológico, de segmentos duodenais pré e pós-papilar de ratos albinos

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    José Antonio Bento

    1998-04-01

    Full Text Available Cada segmento do tubo digestivo tem um padrão próprio de motilidade e toda atividade motora resulta fundamentalmente das propriedades elétricas do músculo liso. Em sua atividade motora o duodeno apresenta funções de mistura e progressão, como também participa do controle do esvaziamento gástrico. Os movimentos do complexo antro-piloro-bulbar são considerados ponto de partida para o peristaltismo intestinal, inclusive com movimentos reversos, sendo que encontramos normalmente uma diminuição progressiva da freqüência das ondas do duodeno ao íleo terminal. Considerando que o duodeno tem características embriológicas, anatômicas, histológicas e bioquímicas que o destacam na fisiologia digestiva, interessou-nos o comportamento motor do segmento duodenal pré e pós-papilar sob estímulo farmacológico. Na realização do trabalho foram utilizados dez ratos albinos dos quais foram retirados os segmentos duodenais pré e pós-papilar. Estes foram divididos em: grupos I e II, pré e pós-papilar, respectivamente. Em cada segmento foram obtidos as diferenças porcentuais (D% do número de ondas e da amplitude máxima no movimento espontâneo e sob estimulo farmacológico do cálcio, potássio, acetilcolina e nor-adrenalina. Foram analisados segundo a ação das drogas dentro de cada grupo e, também, analisadas a ação de cada droga, comparadas entre os grupos. Os resultados mostraram diferenças no delta % do número de ondas sob estímulo farmacológico quando comparados ao movimento espontâneo. Na amplitude máxima, porém, não houve diferença significante. Nas condições de realização do trabalho, pode-se concluir então, que o comportamento motor sob estímulo farmacológico do segmento duodenal pré-papilar isolado de rato é diferente do pós-papilar.Each section of the gastrointestinal tract has its own pattern of motility and the whole motor activity results specially from the electric properties of the smooth muscle

  7. Toric intraocular lens orientation and residual refractive astigmatism: an analysis

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    Potvin R

    2016-09-01

    Full Text Available Rick Potvin,1 Brent A Kramer,2 David R Hardten,3 John P Berdahl4 1Science in Vision, Akron, NY, 2University of Iowa Carver College of Medicine, Iowa City, IA, 3Minnesota Eye Consultants, Minnetonka, MN, 4Vance Thompson Vision, Sioux Falls, SD, USA Purpose: To analyze intraocular lens (IOL orientation data from an online toric back-calculator (astigmatismfix.com for determining if differences were apparent by lens type.Methods: A retrospective review of astigmatismfix.com toric back-calculations that included IOL identification and intended orientation axis.Results: Of 12,812 total validated calculation records, 8,229 included intended orientation and lens identification data. Of the latter, 5,674 calculations (69% involved lenses oriented 5° or more from their intended position. Using estimated toric lens usage data, the percentage of lenses with orientation ≥5° from intended was 0.89% overall, but the percentage varied significantly between specific toric lens brands (P<0.05. The percentage of back-calculations related to lenses that were not oriented as intended was also statistically significantly different by lens brand (P<0.05. When IOLs were misoriented, they were significantly more likely to be misoriented in a counterclockwise direction (P<0.05. This was found to be due to a bias toward counterclockwise orientation observed with one specific brand, a bias that was not observed with the other three brands analyzed here.Conclusion: The percentage of eyes with lens orientation ≥5° from intended in the Toric Results Analyzer data set was <1% of toric IOLs in general, with the relative percentage of Tecnis® Toric IOLs significantly higher than AcrySof® Toric IOLs. Both of these had higher rates than the Staar® Toric and Trulign® Toric lenses, with the availability of higher Tecnis and AcrySof cylinder powers a likely contributing factor. The AcrySof Toric IOL appears to be less likely than the Tecnis Toric IOL to cause residual

  8. Do blue-light filtering intraocular lenses affect visual function?

    Science.gov (United States)

    Lavric, Alenka; Pompe, Manca Tekavcic

    2014-11-01

    To study different aspects of visual function, macular changes, and subjective differences between the eye with an ultraviolet (UV) and blue-light filtering intraocular lens (IOL) and the fellow eye with a UV-light filtering IOL. Thirty patients (60 eyes) with senile cataract had both cataracts extracted, and an IOL was implanted at least 2 years before clinical evaluation. In one eye, AcrySof SA60AT (a UV-light filtering IOL) was implanted, whereas in the contralateral eye, AcrySof IQ SN60WF (a blue-light filtering IOL) was implanted. Each patient underwent visual acuity testing, color vision testing (Ishihara and Farnsworth-Munsell 100-hue tests), and contrast sensitivity (CS) testing. The macula was evaluated with optical coherence tomography and with clinical examination. Patients were asked if they noted any difference between the implanted IOLs concerning visual impression. Subjective visual quality was evaluated using the National Eye Institute Visual Functioning Questionnaire. There was a borderline statistically significant difference in the mean best-corrected visual acuity (p = 0.05). As regards color vision, no significant changes in Ishihara and Farnsworth-Munsell 100-hue error scores were detected between both eyes (p = 0.48 and p = 0.59, respectively). Analysis of CS showed no significant difference between the groups at any spatial frequency. There were also no statistically significant differences in central macular thickness and total macular volume between the two IOL groups (p = 0.72 and p = 0.61, respectively). In both IOL groups, three eyes developed an epiretinal membrane, and six eyes developed early signs of age-related macular degeneration. This study showed no significant effects of a blue-light filtering IOL on visual acuity and no influence on color perception and CS. After more than 2 years, there were no significant differences in macular changes between the IOL groups. Clinical evidence of the effect of a blue-light filtering IOL on

  9. Material properties of various intraocular lenses in an experimental study.

    Science.gov (United States)

    Tehrani, Mana; Dick, H Burkhard; Wolters, Beate; Pakula, Tadeusz; Wolf, Evan

    2004-01-01

    With the recent introduction of small-incision cataract surgery, requirements for intraocular lens (IOL) flexibility, strength and hydrophilicity have rapidly evolved. The IOL surface, however, remains a critical factor influencing uveal biocompatibility. To objectively quantify factors of material properties of various IOLs using contact angle measurements, differential scanning calorimetry, dynamic-mechanical measurements and scanning electron microscopy. In our study, 17 currently available IOLs were investigated using contact angle measurements to assess hydrophilicity and biocompatibility, as well as differential scanning calorimetry for the estimation of glass transition temperature. Mechanical capacity and flexibility were investigated using dynamic-mechanical measurements. Additional analysis of the IOL surface was performed using scanning electron microscopy. The contact angle measurements of the studied IOLs revealed similar values within each group. The silicone IOLs had values between 106 and 119 degrees. The PMMA IOLs were found to have a narrower range of values, between 73.2 and 75.5 degrees. Lenses made of hydrogel had values between 59.2 and 69.1 degrees. The heparin-modified surface showed the lowest contact angle of 56.5 degrees. The glass transition temperature was determined by dynamic differential scanning calorimetry. The resulting values were between 118.8 and 113.5 degrees C for PMMA IOLs, 15.5 and 14.0 degrees C for acrylic IOLs, and -91.7 and -119.6 degrees C for silicone IOLs. The dynamic-mechanical measurements revealed that PMMA lenses manifested characteristics similar to glass, whereas silicone lenses had characteristics similar to rubber. Acrylic lenses were between rubber and glass. Scanning electron microscopy revealed smooth dispersion of fibrin on hydrophobic IOLs and a relative lack of fibrin adhesion on hydrophilic materials. These results demonstrate that material properties of various IOL materials are consistent within

  10. Comparison of two optical biometers in intraocular lens power calculation

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    Sheng Hui

    2014-01-01

    Full Text Available Aims: To compare the consistency and accuracy in ocular biometric measurements and intraocular lens (IOL power calculations using the new optical low-coherence reflectometry and partial coherence interferometry. Subjects and Methods: The clinical data of 122 eyes of 72 cataract patients were analyzed retrospectively. All patients were measured with a new optical low-coherence reflectometry system, using the LENSTAR LS 900 (Haag Streit AG/ALLEGRO BioGraph biometer (Wavelight., AG, and partial coherence interferometry (IOLMaster V.5.4 [Carl Zeiss., Meditec, AG] before phacoemulsification and IOL implantation. Repeated measurements, as recommended by the manufacturers, were performed by the same examiner with both devices. Using the parameters of axial length (AL, corneal refractive power (K1 and K2, and anterior chamber depth (ACD, power calculations for AcrySof SA60AT IOL were compared between the two devices using five formulas. The target was emmetropia. Statistical analysis was performed using Statistical Package for the Social Sciences software (SPSS 13.0 with t-test as well as linear regression. A P value < 0.05 was considered to be statistically significant. Results: The mean age of 72 cataract patients was 64.6 years ± 13.4 [standard deviation]. Of the biometry parameters, K1, K2 and [K1 + K2]/2 values were significantly different between the two devices (mean difference, K1: −0.05 ± 0.21 D; K2: −0.12 ± 0.20 D; [K1 + K2]/2: −0.08 ± 0.14 D. P <0.05. There was no statistically significant difference in AL and ACD between the two devices. The correlations of AL, K1, K2, and ACD between the two devices were high. The mean differences in IOL power calculations using the five formulas were not statistically significant between the two devices. Conclusions: New optical low-coherence reflectometry provides measurements that correlate well to those of partial coherence interferometry, thus it is a precise device that can be used for the

  11. Evaluación del efecto de Lactobacillus spp. en el desarrollo del intestino delgado en pollos de engorde

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    Sandra Paola Rodríguez-González

    2016-01-01

    Full Text Available Los probióticos del tipo Lactobacillus spp. son considerados alternativas promisorias para reemplazar los antibióticos como promotores de crecimiento (APC en las explotaciones avícolas, ya que influyen en el desarrollo poseclosión del tracto gastrointestinal (TGI y en su ecología microbiana. En este estudio se evaluó la morfometría del intestino delgado en pollos de engorde al suministrar 0.5mL/L de un producto comercial a base de Lactobacillus spp. Se utilizaron 200 pollos machos de un día de edad, de la línea Avian Cobb 48, los cuales se distribuyeron, con un diseño completamente al azar, en dos grupos, denominados control y experimento; ambos grupos fueron mantenidos en condiciones similares de alimentación, manejo y sanidad. A los días 7, 15 y 35 de edad se realizó el sacrificio y la necropsia; se disectaron segmentos de duodeno, yeyuno e íleon para su procesamiento con la técnica de coloración de Hematoxilina-Eosina (HE. Los cambios morfométricos de longitud, ancho y cantidad de vellosidades fueron evaluados utilizando un microscopio trinocular con cámara digital Moticam®. Los datos se analizaron usando el programa SPSS versión 19; se realizaron comparaciones de los promedios a través de estadística descriptiva y una prueba ANOVA (p<0,05; se observaron diferencias estimadas significativas (p<0,05 a favor del grupo experimento en el desarrollo poseclosión de los segmentos yeyuno e íleon.

  12. Manejo post sacrificial del cuerpo humano: evidencias e implicaciones rituales en un entierro del Clásico Terminal en Lagartero, Chiapas

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    Judith Lizbeth Ruiz González

    2016-06-01

    Full Text Available Durante 2011 se llevaron a cabo labores de exploración arqueológica en el sitio de Lagartero, en el estado de Chiapas; se recuperó, en un contexto no funerario, un entierro primario con características particulares. Se identificaron segmentos anatómicos incompletos de un individuo masculino, adulto joven, con marcas de corte distribuidas en varias áreas de los huesos. Se puede considerar que se trata de evidencia del tratamiento post sacrificial del cuerpo humano y el posible aprovechamiento de alguna de sus partes con propósitos rituales o como materia prima para la manufactura de utensilios, herramientas, ornatos u otros objetos. A partir de la concepción maya de lo que es el cuerpo humano se pretende entender el porqué del manejo post sacrificial que se dio al cadáver.

  13. Tlaxcala: entre la modernización y la frontera del retroceso: del Prosperato a la Revolución Mexicana

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    Jenny Zapata de la Cruz

    2010-08-01

    Full Text Available El trabajo se divide en tres segmentos: el primero responde a la intervención del Estado en la modernización de Tlaxcala en la última década del siglo XIX; el segundo expone el desgaste de las infraestructuras por el mal uso de los revolucionarios; finalmente se presenta el rumbo de la entidad a partir de los años 20 del siglo XX. Se pretende enfocar: que la modernización en Tlaxcala es un proceso de larga duración dirigida por un Estado “paternalista”; y que las vías de la modernidad progresista pueden apreciarse en la infraestructura y grupos de poder.

  14. Callus induction in leaf segments of Croton urucurana Baill Indução de calos em segmentos foliares de sangra d'água (Croton urucurana Baill

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    Ednabel Caracas Lima

    2008-02-01

    Full Text Available Croton urucurana Baill., a species belonging to the family Euphorbiaceae, can be useful in the recovery of degraded riparian areas. In the traditional medicine, it is widely used as cicatrizant and in the treatment of rheumatism. However, its seeds present dormancy and low viability, making the propagation of this species a challenge. With the objective of establishing an alternative route for the propagation, the effect of different concentrations of 2,4-D (2,4- dichlorophenoxyacetic acid with BAP (6-benzylaminopurine or TDZ (thidiazuron and of NAA (1-naphthaleneacetic acid with BAP and their possible combinations were evaluated for callus induction in leaf segments. Callus fresh mass was evaluated forty-five days after inoculation. The isolated use of BAP and the combination of NAA with BAP did not promote calogenesis in leaf segments. Even though the combination of 2,4-D with BAP or TDZ had induced the formation of callus, it was the isolated use of 2,4-D that provided the highest callus fresh mass.A sangra d'água, espécie pertencente à família Euphorbiaceae, apresenta potencial na recuperação de matas ciliares degradadas e é extensamente utilizada na medicina tradicional, como cicatrizante e no tratamento de reumatismos. Entretanto, suas sementes apresentam dormência e baixa viabilidade, dificultando a propagação desta espécie. Avaliou-se o efeito de diferentes concentrações de 2,4-D e BAP ou TDZ e de ANA e BAP, com suas possíveis combinações, na indução de calos em segmentos foliares de sangra d'água. Quarenta e cinco dias após a inoculação, foi avaliado o peso fresco dos calos. O uso de BAP isoladamente e a combinação entre ANA e BAP não promoveram calogênese em segmentos foliares de sangra d'água. Embora a combinação de 2,4-D e BAP ou TDZ tenha induzido a formação de calos, o uso isolado de 2,4-D proporcionou o maior peso fresco destes.

  15. Validação prospectiva do escore de risco dante pazzanese em síndrome coronariana aguda sem supradesnivelamento do segmento ST

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    Elizabete Silva dos Santos

    2013-09-01

    Full Text Available FUNDAMENTO: Em Síndrome Coronariana Aguda (SCA sem Supradesnivelamento do segmento ST (SST é importante estimar a probabilidade de eventos adversos. Para esse fim, as diretrizes recomendam modelos de estratificação de risco. O escore de risco Dante Pazzanese (escore DANTE é um modelo simples de estratificação de risco, composto das variáveis: aumento da idade (0 a 9 pontos; antecedente de diabete melito (2 pontos ou acidente vascular encefálico (4 pontos; não uso de inibidor da enzima conversora da angiotensina (1 ponto; elevação da creatinina (0 a 10 pontos; combinação de elevação da troponina e depressão do segmento ST (0 a 4 pontos. OBJETIVO: Validar o escore DANTE em pacientes com SCA sem SST. MÉTODOS: Estudo prospectivo, observacional, com inclusão de 457 pacientes, de setembro de 2009 a outubro de 2010. Os pacientes foram agrupados em: muito baixo, baixo, intermediário e alto risco de acordo com a pontuação do modelo original. A habilidade preditiva do escore foi avaliada pela estatística-C. RESULTADOS: Foram 291 (63,7% homens e a média da idade 62,1 anos (11,04. Dezessete pacientes (3,7% apresentaram o evento de morte ou (reinfarto em 30 dias. Ocorreu aumento progressivo na proporção do evento, com aumento da pontuação: muito baixo risco = 0,0%; baixo risco = 3,9%; risco intermediário = 10,9%; alto risco = 60,0%; p < 0,0001. A estatística-C foi de 0,87 (IC 95% 0,81-0,94; p < 0,0001. CONCLUSÃO: O escore DANTE apresentou excelente habilidade preditiva para ocorrência dos eventos específicos e pode ser incorporado na avaliação prognóstica de pacientes com SCA sem SST.

  16. Reference intervals for intraocular pressure measured by rebound tonometry in ten raptor species and factors affecting the intraocular pressure.

    Science.gov (United States)

    Reuter, Anne; Müller, Kerstin; Arndt, Gisela; Eule, Johanna Corinna

    2011-09-01

    Intraocular pressure (IOP) was measured with the TonoVet rebound tonometer in 10 raptor species, and possible factors affecting IOP were investigated. A complete ophthalmic examination was performed, and IOP was assessed in 2 positions, upright and dorsal recumbency, in 237 birds belonging to the families Accipitridae, Falconidae, Strigidae, and Tytonidae. Mean IOP values of healthy eyes were calculated for each species, and differences between families, species, age, sex, left and right eye, as well as the 2 body positions were evaluated. Physiologic fluctuations of IOP were assessed by measuring IOP serially for 5 days at the same time of day in 15 birds of 3 species. Results showed IOP values varied by family and species, with the following mean IOP values (mm Hg +/- SD) determined: white-tailed sea eagle (Haliaeetus albicilla), 26.9 +/- 5.8; red kite (Milvus milvus), 13.0 +/- 5.5; northern goshawk (Accipiter gentilis), 18.3 +/- 3.8; Eurasian sparrowhawk (Accipiter nisus), 15.5 +/- 2.5; common buzzard (Buteo buteo), 26.9 +/- 7.0; common kestrel (Falco tinnunculus), 9.8 +/- 2.5; peregrine falcon, (Falco peregrinus), 12.7 +/- 5.8; tawny owl (Strix aluco), 9.4 +/- 4.1; long-eared owl (Asio otus), 7.8 +/- 3.2; and barn owl (Tyto alba), 10.8 +/- 3.8. No significant differences were found between sexes or between left and right eyes. In goshawks, common buzzards, and common kestrels, mean IOP was significantly lower in juvenile birds than it was in adult birds. Mean IOP differed significantly by body position in tawny owls (P = .01) and common buzzards (P = .04). By measuring IOP over several days, mean physiologic variations of +/- 2 mm Hg were detected. Differences in IOP between species and age groups should be considered when interpreting tonometric results. Physiologic fluctuations of IOP may occur and should not be misinterpreted. These results show that rebound tonometry is a useful diagnostic tool in measuring IOP in birds of prey because it provides rapid

  17. Comparison between bilateral implantation of a trifocal intraocular lens and blended implantation of two bifocal intraocular lenses

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    Vilar C

    2017-08-01

    Full Text Available César Vilar,1,2 Wilson Takashi Hida,1–3 André Lins de Medeiros,1,2 Klayny Rafaella Pereira Magalhães,2 Patrick Frensel de Moraes Tzelikis,1,2 Mario Augusto Pereira Dias Chaves,2,4 Antônio Francisco Pimenta Motta,2,3 Pedro Carlos Carricondo,1–3 Milton Ruiz Alves,3 Walton Nosé5 1Cataract Division, Brasília Ophthalmologic Hospital (HOB, Brasília-DF, Brazil; 2Renato Ambrosio Ophthalmologic Research Center (CEORA, 3Ophthalmology Department, São Paulo University – USP, São Paulo-SP, Brazil; 4Cataract Division, ProVisão, João Pessoa-PB, Brazil; 5Ophthalmology Department, Paulista Medical School – UNIFESP, São Paulo-SP, Brazil Purpose: To compare visual outcomes and performance between bilateral implantation of a diffractive trifocal intraocular lens (IOL Acrysof®PanOptix® TFNT00 and blended implantation of two different near add power bifocal IOLs: Acrysof® Restor® SV25T0 in dominant eye and Acrysof® Restor® SN6AD1 in the nondominant eye.Methods: This prospective, nonrandomized, consecutive and comparative study assessed 20 patients (40 eyes who had bilateral cataract surgery performed using the IOLs described. Patients were divided into groups, bilateral trifocal implant and blended implant. Evaluation included measurement of binocular uncorrected and corrected distance visual acuity at 4 m (UDVA, CDVA and uncorrected intermediate (60 cm and near (at 40 cm visual acuity; contrast sensitivity (CS and visual defocus curve.Results: Postoperative CDVA comparison showed no statistical significance between groups. UDVA was significantly better in the trifocal groups. Under photopic conditions, the trifocal group had better CS in higher frequencies with and without glare. The binocular defocus curve demonstrated a trifocal behavior in both groups, with the bilateral trifocal group exhibiting better performance for intermediate vision.Conclusion: Both lens combinations were able to provide good near, intermediate and distance vision

  18. Exames radiográficos simples e tomográficos do segmento lombossacro da coluna vertebral em cães da raça Pastor Alemão: estudo comparativo

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    Thelma Regina Cintra da Silva

    2009-08-01

    Full Text Available O termo síndrome da cauda equina (SCE define as manifestações clínicas oriundas da disfunção sensorial e/ou motora causada pela lesão das raízes nervosas que formam a porção terminal da medula espinhal. A estenose lombossacra é a causa mais comum, correlacionando-se às alterações das partes moles e/ou tecidos ósseos neste segmento. Este estudo teve por objetivo realizar uma análise crítica da contribuição dos métodos de imagem, quais sejam exames: radiográfico simples e tomográfico, para avaliação do segmento lombossacro em 30 cães da raça Pastor Alemão. Sendo treze animais pertencentes ao grupo (A sem manifestações clínicas e alterações radiográficas no segmento lombosacro; doze animais pertencentes ao grupo (B sem manifestações clínicas com alterações radiográficas no segmento lombossacro e cinco animais pertencentes ao grupo (C com manifestações clínicas e portadores de alterações radiográficas no segmento lombossacro. Todos os exames foram submetidos a um protocolo de avaliação. O exame tomográfico mostrou-se superior na avaliação do canal vertebral, foramens intervertebrais e processos articulares, os quais puderam ser avaliados com maior riqueza de detalhes. Concluiu-se com esta pesquisa que as duas modalidades de imagem se complementam, constituindo ferramentas importantes na avaliação clínico-cirúrgica do segmento lombossacro, auxiliando no diagnóstico, estabelecimento do prognóstico e da terapêutica a ser adotada.

  19. Endophthalmitis due to an intra-ocular linear foreign body in a cat

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    Esmeralda Delgado

    2015-05-01

    Full Text Available Case summary An unusual case of an intraocular linear foreign body that migrated from the oral cavity, causing a severe endophthalmitis, in a cat is described. A 2-year-old female domestic shorthair cat presented with signs of infection from the left eye that had begun 2 weeks previously. Despite having been prescribed oral and topical antibiotics, there was a progressive worsening of the clinical signs. On ophthalmic examination the cat presented with severe endophthalmitis, secondary glaucoma and exposure keratitis of the left eye. Radiography demonstrated the presence of an intraocular linear metallic foreign body compatible with a sewing needle. During enucleation, when the globe was extracted, the sewing needle stayed in the orbit. When the needle was pulled away, a piece of thread was also retrieved, which demonstrated that the linear foreign body had migrated retrogradely from the oral cavity to the orbit through the pterygopalatine fossa. Surgical recovery was uneventful. Relevance and novel information Intraocular foreign bodies may present in a variety of ways, which may hinder their clinical detection. The management and prognosis depend on the composition and location of the foreign body, as well as the possible presence of secondary infection. To the author’s knowledge, this is the first time that a case of severe endophthalmitis following retrograde intraocular migration of a linear foreign body from the oral cavity to the orbit through the pterygopalatine fossa in a cat has been reported.

  20. Associations with intraocular pressure across Europe: The European Eye Epidemiology (E-3) Consortium

    NARCIS (Netherlands)

    Khawaja, Anthony P.; Springelkamp, Henriët; Creuzot-Garcher, Catherine; Delcourt, Cécile; Hofman, Albert; Höhn, René; Iglesias, Adriana I.; Wolfs, Roger C. W.; Korobelnik, Jean-François; Silva, Rufino; Topouzis, Fotis; Williams, Katie M.; Bron, Alain M.; Buitendijk, Gabriëlle H. S.; Cachulo, Maria da Luz; Cougnard-Grégoire, Audrey; Dartigues, Jean-François; Hammond, Christopher J.; Pfeiffer, Norbert; Salonikiou, Angeliki; van Duijn, Cornelia M.; Vingerling, Johannes R.; Luben, Robert N.; Mirshahi, Alireza; Lamparter, Julia; Klaver, Caroline C. W.; Jansonius, Nomdo M.; Foster, Paul J.; Acar, Niyazi; Anastosopoulos, Eleftherios; Azuara-Blanco, Augusto; Bergen, Arthur; Bertelsen, Geir; Binquet, Christine; Bird, Alan; Brétillon, Lionel; Bron, Alain; Buitendijk, Gabrielle; Cachulo, Maria Luz; Chakravarthy, Usha; Chan, Michelle; Chang, Petrus; Colijn, Annemarie; Cumberland, Philippa; Cunha-Vaz, José; Daien, Vincent; Deak, Gabor; Delyfer, Marie-Noëlle; Hollander, Anneke den; Dietzel, Martha; Erke, Maja Gran; Fauser, Sascha; Finger, Robert; Fletcher, Astrid; Foster, Paul; Founti, Panayiota; Göbel, Arno; Gorgels, Theo; Grauslund, Jakob; Grus, Franz; Hammond, Christopher; Helmer, Catherine; Hense, Hans-Werner; Hermann, Manuel; Hoehn, René; Hogg, Ruth; Holz, Frank; Hoyng, Carel; Jansonius, Nomdo; Janssen, Sarah; Khawaja, Anthony; Klaver, Caroline; Le Goff, Mélanie; Leal, Sergio; Lechanteur, Yara; Lehtimäki, Terho; Lotery, Andrew; Leung, Irene; Mauschitz, Matthias; Merle, Bénédicte; Meyer Zu Westrup, Verena; Midena, Edoardo; Miotto, Stefania; Mohan-Saïd, Sadek; Muldrew, Alyson; Mueller, Michael; Nunes, Sandrina; Oexle, Konrad; Peto, Tunde; Piermarocchi, Stefano; Prokofyeva, Elena; Rahi, Jugnoo; Raitakari, Olli; Ribeiro, Luisa; Rougier, Marie-Bénédicte; Sahel, José; Salonikiou, Aggeliki; Sanchez, Clarisa; Schmitz-Valckenberg, Steffen; Schweitzer, Cédric; Segato, Tatiana; Shehata, Jasmin; Silvestri, Giuliana; Simader, Christian; Souied, Eric; Springelkamp, Henriet; Tapp, Robyn; Verhoeven, Virginie; Von Hanno, Therese; Vujosevic, Stela; Williams, Katie; Wolfram, Christian; Yip, Jennifer; Zerbib, Jennyfer; Zwiener, Isabella

    2016-01-01

    Raised intraocular pressure (IOP) is the most important risk factor for developing glaucoma, the second commonest cause of blindness globally. Understanding associations with IOP and variations in IOP between countries may teach us about mechanisms underlying glaucoma. We examined cross-sectional

  1. Use of a new intra-ocular spectral domain optical coherence tomography in vitreoretinal surgery

    NARCIS (Netherlands)

    Mura, Marco; Iannetta, Danilo; Nasini, Francesco; Barca, Francesco; Peiretti, Enrico; Engelbrecht, Leonore; de Smet, Marc D.; Verbraak, Frank

    2016-01-01

    To describe the use of a novel intra-ocular side-scanning probe enabling the acquisition of spectral-domain optical coherence tomography (SD-OCT) images during surgery in a series of patients with complex forms of retinal detachment. A 23-gauge, side-scanning SD-OCT probe (C7 System; LightLab

  2. Baseline Intraocular Pressure Is Associated with Subjective Sensitivity to Physical Exertion in Young Males

    Science.gov (United States)

    Vera, Jesús; Jiménez, Raimundo; García, José Antonio; Perales, José Cesar; Cárdenas, David

    2018-01-01

    Purpose: The purposes of this study were to (a) investigate the effect of physical effort (cycling for 60 min at 60 ± 5% of individually computed reserve heart-rate capacity), combined with 2 different levels of cognitive demand (2-back, oddball), on intraocular pressure (IOP) and subjective judgments of perceived exertion (ratings of perceived…

  3. Toric Intraocular Lenses in the Correction of Astigmatism During Cataract Surgery

    DEFF Research Database (Denmark)

    Kessel, Line; Andresen, Jens; Tendal, Britta

    2016-01-01

    TOPIC: We performed a systematic review and meta-analysis to evaluate the benefit and harms associated with implantation of toric intraocular lenses (IOLs) during cataract surgery. Outcomes were postoperative uncorrected distance visual acuity (UCDVA) and distance spectacle independence. Harms we...

  4. time effect of exercise on intraocular pressure in a Nigerian population

    African Journals Online (AJOL)

    Numerous international studies have indicated that several physiological changes can influence the intraocular pressure (IOP) of subjects. In order to assess visual health status through physiological changes, the effects of rest and exercise on IOP were investigated in a Nigerian community. The research involved 24 ...

  5. Intraocular Gnathostoma spinigerum. Clinicopathologic study of two cases with review of literature.

    Science.gov (United States)

    Biswas, J; Gopal, L; Sharma, T; Badrinath, S S

    1994-01-01

    Live intraocular nematode is a rare occurrence that is mostly reported in Southeast Asian countries. Common nematodes that are seen live in the eye are microfilaria, Gnathostoma, and Angiostrongylus. Approximately 12 cases of intraocular gnathostomiasis have been reported in the literature. Two cases of intraocular gnathostoma, removed by vitrectomy in the first case and by paracentesis in the second case, are reported. Morphologic study of the parasites in wet preparation was performed under dissecting microscope and fixed in Karnovosky's fixative. Light microscopic and scanning electron microscopic studies were also performed. The first patient had anterior uveitis, multiple iris holes, and dense vitreous haze with fibrous proliferation over the optic disc. On resolution of the vitreous haze, a live worm was seen in the vitreous cavity. The second patient had anterior uveitis with secondary glaucoma, multiple iris holes, mild vitritis, and focal subretinal haemorrhage with subretinal tracts. Four days later a live worm was seen in the anterior chamber and removed. Microscopic study of the parasites from both patients revealed typical head bulb with four circumferential rows of hooklets, and fine cuticular spines were seen on the surface of the body. Iris holes, uveitis, and subretinal haemorrhage with subretinal tract can be characteristic features of intraocular gnathostomiasis. Identification of this parasite can be made by typical features, which can be identified on light and scanning electron microscopic study.

  6. Common Genetic Determinants of Intraocular Pressure and Primary Open-Angle Glaucoma

    NARCIS (Netherlands)

    van Koolwijk, Leonieke M. E.; Ramdas, Wishal D.; Ikram, M. Kamran; Jansonius, Nomdo M.; Pasutto, Francesca; Hysi, Pirro G.; Macgregor, Stuart; Janssen, Sarah F.; Hewitt, Alex W.; Viswanathan, Ananth C.; ten Brink, Jacoline B.; Hosseini, S. Mohsen; Amin, Najaf; Despriet, Dominiek D. G.; Willemse-Assink, Jacqueline J. M.; Kramer, Rogier; Rivadeneira, Fernando; Struchalin, Maksim; Aulchenko, Yurii S.; Weisschuh, Nicole; Zenkel, Matthias; Mardin, Christian Y.; Gramer, Eugen; Welge-Luessen, Ulrich; Montgomery, Grant W.; Carbonaro, Francis; Young, Terri L.; Bellenguez, Celine; McGuffin, Peter; Foster, Paul J.; Topouzis, Fotis; Mitchell, Paul; Wang, Jie Jin; Wong, Tien Y.; Czudowska, Monika A.; Hofman, Albert; Uitterlinden, Andre G.; Wolfs, Roger C. W.; de Jong, Paulus T. V. M.; Oostra, Ben A.; Paterson, Andrew D.; Mackey, David A.; Bergen, Arthur A. B.; Reis, Andre; Hammond, Christopher J.; Vingerling, Johannes R.; Lemij, Hans G.; Klaver, Caroline C. W.; van Duijn, Cornelia M.

    2012-01-01

    Intraocular pressure (IOP) is a highly heritable risk factor for primary open-angle glaucoma and is the only target for current glaucoma therapy. The genetic factors which determine IOP are largely unknown. We performed a genome-wide association study for IOP in 11,972 participants from 4

  7. Effect of oxymetazoline nasal spray on intraocular pressure and retrobulbar hemodynamics.

    Science.gov (United States)

    Arikan, Osman Kursat; Akarsu, Cengiz; Unal, Birsen; Ergin, Ahmet; Koç, Can

    2006-02-01

    To determine the effect of oxymetazoline nasal spray on intraocular pressure and retrobulbar hemodynamics in patients with open-angle glaucoma and to compare the results with those measured in healthy control participants. Controlled, prospective clinical trial. University hospital. Thirty patients with open-angle glaucoma and 30 healthy volunteers as controls were topically self-administered oxymetazoline nasal spray three times a day (one spray in each nostril of 0.05% concentration) for 5 days continuously. Intraocular pressure and retrobulbar hemodynamics were measured in glaucomatous and normal eyes at baseline and at the end of oxymetazoline application . Oxymetazoline nasal spray lowered intraocular pressure significantly in both the glaucoma group (p = .02) and the control group (p = .001) after 5 days of treatment. The systemic parameters in the glaucoma and control groups (systolic blood pressure, p = .14 and p = .17; diastolic blood pressure, p = .18 and p = .49; and pulse rate, p = .06 and p = .50, respectively) did not show statistically significant differences during the study period. Additionally, except with a significant decrease in the resistivity index of the central retinal artery in the glaucoma patients (p = .001), oxymetazoline nasal spray did not result in any significant changes in the retrobulbar hemodynamics in both the glaucoma and control groups. This study showed that a 5-day treatment with oxymetazoline nasal spray reduced intraocular pressure in both healthy controls and patients with glaucoma under treatment. In addition, it had no significant adverse effects on the retrobulbar hemodynamics.

  8. Management of subluxated capsular bag-fixated intraocular lenses using a capsular anchor

    NARCIS (Netherlands)

    Ton, Yokrat; Naftali, Modi; Lapid Gortzak, Ruth; Assia, Ehud I.

    2016-01-01

    We describe the use of the capsular anchor (AssiAnchor) to manage a subluxated intraocular lens (IOL) in the capsular bag. The anchor comprises 2 prongs that hold the anterior lens capsule and a central rod that is sutured to the scleral wall, enabling centration of the IOL-capsular bag complex. Six

  9. Influence of Multifocal Intraocular Lenses on Standard Automated Perimetry Test Results

    NARCIS (Netherlands)

    Aychoua, Nancy; Montolio, Francisco G. Junoy; Jansonius, Nomdo M.

    Importance: A multifocal intraocular lens (MFIOL) allows for spectacle independence after cataract surgery and is thus a seemingly attractive option. However, several optical limitations have been reported or can be hypothesized. Objective: To evaluate the influence of an MFIOL on standard automated

  10. ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure

    NARCIS (Netherlands)

    H. Springelkamp (Henriët); A.I. Iglesias González (Adriana); G. Cuellar-Partida (Gabriel); N. Amin (Najaf); K.P. Burdon (Kathryn); E.M. van Leeuwen (Elisa); P. Gharahkhani (Puya); A. Mishra (Aniket); S.J. van der Lee (Sven); A.W. Hewit (Alex); F. Rivadeneira Ramirez (Fernando); A.C. Viswanathan (Ananth); R.C.W. Wolfs (Roger); N.G. Martin (Nicholas); W.D. Ramdas (Wishal); L.M.E. van Koolwijk (Leonieke); C.E. Pennell (Craig E.); J.R. Vingerling (Hans); J.E. Mountain (Jenny E.); A.G. Uitterlinden (André); A. Hofman (Albert); P. Mitchell (Paul); H.G. Lemij (Hans); J.J. Wang (Jie Jin); C.C.W. Klaver (Caroline); D.A. Mackey (David); J.E. Craig (Jamie E.); C.M. van Duijn (Cornelia); S. MacGregor (Stuart)

    2015-01-01

    textabstractPrimary open-angle glaucoma (POAG) is a blinding disease. Two important risk factors for this disease are a positive family history and elevated intraocular pressure (IOP), which is also highly heritable. Genes found to date associated with IOP and POAG are ABCA1, CAV1/CAV2, GAS7 and

  11. Intraocular and extraocular hemorrhage associated with ligature release of non-valved glaucoma drainage implant

    Directory of Open Access Journals (Sweden)

    Michelle Go

    2017-04-01

    Conclusions and importance: This is the first report of a rare occurrence of intraocular and extraocular hemorrhage associated following spontaneous release of ligature of a non-valved glaucoma drainage implant. The presumed mechanism was sudden shallowing of the anterior chamber resulting in the tube irritating uveal vasculature. We do not have an explanation for the extraocular blood.

  12. Risk of reactivation of toxoplasmic retinitis following intraocular procedures without the use of prophylactic therapy.

    Science.gov (United States)

    Heringer, Gustavo C; Oueghlani, Evelyne; Dell'Omo, Roberto; Curi, André L L; Oréfice, Fernando; Pavésio, Carlos E

    2014-09-01

    Toxoplasmic retinochoroiditis is the commonest known cause of posterior uveitis worldwide and reactivation is unpredictable. Based on results from one study, the authors proposed that antitoxoplasmic therapy should be initiated as prophylaxis for intraocular surgery in patients with toxoplasmic scars. The aim of this study is to analyse the risk of toxoplasmic retinochoroiditis reactivation following intraocular procedures. Retrospective analysis of the medical records of a total of 69 patients who underwent intraocular surgery and presented with toxoplasmic retinochoroiditis scars. No patient received prophylactic antitoxoplasmic therapy. Reactivation following the surgical procedure occurred in four cases, with one at 3 months and the others respectively at 13, 14 and 17 months. Our study shows that intraocular surgery did not result in a significant reactivation rate of toxoplasmic retinochoroiditis in the absence of preoperative prophylactic antitoxoplasmic therapy. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  13. Iris-fixated anterior chamber phakic intraocular lens for myopia moves posteriorly with mydriasis.

    NARCIS (Netherlands)

    Cruysberg, L.P.J.; Doors, M.; Berendschot, T.T.; Brabander, J. De; Webers, C.A.; Nuijts, R.M.

    2009-01-01

    PURPOSE: To elucidate the physiological characteristics of eyes implanted with iris-fixated anterior chamber phakic intraocular lenses (pIOLs), which are increasingly being used for the correction of higher myopic and hyperopic refractive errors. METHODS: In a case series of 20 patients (39 eyes),

  14. Reliability of intraocular pressure measurement with the Goldmann applanation tonometer in epidemiological studies

    NARCIS (Netherlands)

    I. Dielemans (Ida); J.R. Vingerling (Hans); A. Hofman (Albert); D.E. Grobbee (Diederick); P.T.V.M. de Jong (Paulus)

    1994-01-01

    textabstractThe reproducibility of intraocular pressure (IOP) measurement with the Goldmann applanation tonometer was investigated as part of a population-based epidemiological study. Sixty-two subjects were examined in a first measurement session. The IOP was measured three times consecutively in

  15. The case for intraocular delivery of PPAR agonists in the treatment of diabetic retinopathy.

    LENUS (Irish Health Repository)

    Treacy, Maxwell P

    2012-09-01

    Systemic therapeutics targeting the peroxisome proliferator-activated receptors have been found to be beneficial in the treatment of diabetic retinopathy. In this paper, we provide a rationale for the use of these therapeutics as intraocular agents. In addition, we introduce the peroxisome proliferator-activated receptors and describe their functions in response to the drugs.

  16. Endotoxin-induced uveitis in the rat. The significance of intraocular interleukin-6

    NARCIS (Netherlands)

    Hoekzema, R.; Verhagen, C.; van Haren, M.; Kijlstra, A.

    1992-01-01

    The potential role of interleukin-6 (IL-6) was studied as an inflammatory mediator of endotoxin (or lipopolysaccharide [LPS])-induced uveitis (EIU) in the rat. In young Lewis rats, levels of intraocular IL-6, but not serum IL-6, correlated with the severity of uveitis and with aqueous humor protein

  17. Efecto del ayuno sobre la absorción de Ciprofloxacina : Modelo in vitro

    OpenAIRE

    Volonté, María Guillermina

    1993-01-01

    Se analiza el efecto del ayuno sobre la absorción gastrointestinal de ciprofloxacina mediante la utilización de un modelo in vitro que emplea estómagos y segmentos intestinales proximales aislados de ratas, separadas en dos lotes, uno de ellos sometido a un ayuno de 16 horas y el otro liberado a una dieta de alimento balanceado a voluntad. Los resultados muestran una transferencia intestinal parcial de la droga y una absorción estomacal despreciable, comprobándose que el ayuno no tiene efecto...

  18. Plan de negocio para el relanzamiento de la marca Kawasaki del grupo Crosland

    OpenAIRE

    Hart Soto, Jean Paul; Gálvez Guerrero, Tulio Enrique; Montoya Vera, Aida Gisela

    2016-01-01

    Kawasaki es una marca reconocida a nivel mundial con alto nivel de recordación, lo cual no está siendo explotado. Es un producto de calidad orientado a un segmento de usuarios exigente. El costo de ventas al cierre del 2014 ascendió al 80% de las ventas; la utilidad Neta y EBITDA fueron negativos, toso esto se revertirá incrementando las ventas a través de esfuerzos en publicidad y marketing, y una tienda propia para la marca Kawasaki. En esto se centra la propuesta de relanzamiento de la lín...

  19. Intraocular pressure-lowering effect of oral paracetamol and its in vitro corneal penetration properties

    Directory of Open Access Journals (Sweden)

    Mohamed N

    2013-01-01

    Full Text Available Nabiel Mohamed, David MeyerDivision of Ophthalmology, Faculty of Medicine and Health Sciences, University of Stellenbosch, Cape Town, South AfricaBackground: Several studies have confirmed the ability of cannabinoids to reduce intraocular pressure. Experimental data recently demonstrated unequivocally that the analgesic effect of paracetamol is due to its indirect action on cannabinoid receptors. The question then arises as to whether paracetamol can reduce intraocular pressure via its effect on intraocular cannabinoid receptors.Methods: A 2-week, prospective, randomized, controlled, single-center, parallel-group pilot study was carried out to determine the efficacy and safety of paracetamol 1 g orally administered every 6 hours in adult patients with primary or secondary open angle glaucoma as compared with topical levobunolol 0.5% twice a day. Patient well-being was closely monitored throughout the study and focused on hepatic safety in accordance with Drug-Induced Liver Injury Network criteria. The in vitro diffusion kinetics of acetaminophen in a phosphate-buffered solution in rabbit and human corneas was also investigated, with the view to a topical application.Results: Eighteen adult patients were enrolled in the study, with nine in the topical levobunolol group and nine in the oral paracetamol group. In the levobunolol group, the mean reduction in intraocular pressure at day 7 was 7.5 mmHg (P < 0.008 and at day 14 was 9.1 mmHg (P < 0.005, from a mean baseline intraocular pressure of 29.6 mmHg. The corresponding figures for the paracetamol group were 8.8 mmHg (P < 0.0004 at day 7 and 6.5 mmHg (P < 0.004 at day 14, from a mean baseline intraocular pressure of 29.4 mmHg. Both study regimens were well tolerated. No serious treatment-related adverse events were reported in either of the treatment groups. Liver function tests, systolic/diastolic blood pressure, or heart rate remained unchanged in both groups during the 2 weeks of the study. In

  20. Comportamiento del mercado turístico extranjero en el Caribe Mexicano

    Directory of Open Access Journals (Sweden)

    Dr. Francisco J. Güemes-Ricalde

    2009-11-01

    Full Text Available El Caribe mexicano atrae visitantes de regiones distintas en diferentes épocas del año. A los prestadores de servicios turísticos les resulta difícil conocer y separar las preferencias de actividades que realizan los visitantes de cada país. Arriban visitantes mexicanos y extranjeros, las preferencias de estos últimos en relación a la demanda de servicios son diferentes. Contrario a lo que se conocía, el estudio de mercado determinó que la demanda mexicana representa un mercado importante en marcadas épocas del año. Se calcula que cada año alrededor de dos millones de turistas nacionales arriban a la Riviera y Costa Maya en la región norte de Quintana Roo. Conocer las preferencias de consumo de los diferentes segmentos de turistas y la forma en que evalúan la posibilidad de demandar los servicios turísticos da la pauta para ofrecérselos en forma diferenciada y adecuada a cada segmento y en relación a cada una de las diversas actividades turísticas que realizan, entre ellas el ecoturismo de la cual poco se conoce en esta región del país.

  1. Bartonella and intraocular inflammation: a series of cases and review of literature

    Directory of Open Access Journals (Sweden)

    Kalogeropoulos C

    2011-06-01

    Full Text Available Chris Kalogeropoulos1, Ioannis Koumpoulis1, Andreas Mentis2, Chrisavgi Pappa1, Paraskevas Zafeiropoulos1, Miltiadis Aspiotis11Department of Ophthalmology, Medical School, University of Ioannina, Greece; 2Laboratory of Medical Microbiology, Hellenic Pasteur Institute, Athens, GreecePurpose: To present various forms of uveitis and/or retinal vasculitis attributed to Bartonella infection and review the impact of this microorganism in patients with uveitis.Methods: Retrospective case series study. Review of clinical records of patients diagnosed with Bartonella henselae and Bartonella quintana intraocular inflammation from 2001 to 2010 in the Ocular Inflammation Department of the University Eye Clinic, Ioannina, Greece. Presentation of epidemiological and clinical data concerning Bartonella infection was provided by the international literature.Results: Eight patients with the diagnosis of Bartonella henselae and two patients with B. quintana intraocular inflammation were identified. Since four patients experienced bilateral involvement, the affected eyes totaled 14. The mean age was 36.6 years (range 12–62. Uveitic clinical entities that we found included intermediate uveitis in seven eyes (50%, vitritis in two eyes (14.2%, neuroretinitis in one eye (7.1%, focal retinochoroiditis in one eye (7.1%, branch retinal vein occlusion (BRVO due to vasculitis in one eye (7.1%, disc edema with peripapillary serous retinal detachment in one eye (7.1%, and iridocyclitis in one eye (7.1%. Most of the patients (70% did not experience systemic symptoms preceding the intraocular inflammation. Antimicrobial treatment was efficient in all cases with the exception of the case with neuroretinitis complicated by anterior ischemic optic neuropathy and tubulointerstitial nephritis.Conclusion: Intraocular involvement caused not only by B. henselae but also by B. quintana is being diagnosed with increasing frequency. A high index of suspicion is needed because the

  2. Experimental differentiation of intraocular masses using ultrahigh-field magnetic resonance imaging--a case series.

    Directory of Open Access Journals (Sweden)

    Karen Falke

    Full Text Available PURPOSE: The case reports presented here were compiled to demonstrate the potential for improved diagnosis and monitoring of disease progress of intraocular lesions using ultrahigh-field magnetic resonance microscopy (MRM at 7.1 Tesla. METHODS: High-resolution ex vivo ocular magnetic resonance (MR images were acquired on an ultrahigh-field MR system (7.1 Tesla, ClinScan, Bruker BioScan, Germany using a 2-channel coil with 4 coil elements and T2-weighted turbo spin echo (TSE sequences of human eyes enucleated because of different intraocular lesions. Imaging parameters were: 40×40 mm field of view, 512×512 matrix, and 700 µm slice thickness. The results were correlated with in vivo ultrasound and histology of the enucleated eyes. RESULTS: Imaging was performed in enucleated eyes with choroidal melanoma, malignant melanoma of iris and ciliary body with scleral perforation, ciliary body melanoma, intraocular metastasis of esophageal cancer, subretinal bleeding in the presence of perforated corneal ulcer, hemorrhagic choroidal detachment, and premature retinopathy with phthisis and ossification of bulbar structures. MR imaging allowed differentiation between solid and cystic tumor components. In case of hemorrhage, fluid-fluid levels were identified. Melanin and calcifications caused significant hypointensity. Microstructural features of eye lesions identified by MRM were confirmed by histology. CONCLUSION: This study demonstrates the potential of MRM for the visualization and differential diagnosis of intraocular lesions. At present, the narrow bore of the magnet still limits the use of this technology in humans in vivo. Further advances in ultrahigh-field MR imaging will permit visualization of tumor extent and evaluation of nonclassified intraocular structures in the near future.

  3. Multifocal versus monofocal intraocular lenses after cataract extraction

    Directory of Open Access Journals (Sweden)

    Daniel Calladine

    Full Text Available BACKGROUND: Good unaided distance visual acuity is now a realistic expectation following cataract surgery and intraocular lens (IOL implantation. Near vision, however, still requires additional refractive power, usually in the form of reading glasses. Multiple optic (multifocal IOLs are available which claim to allow good vision at a range of distances. It is unclear whether this benefit outweighs the optical compromises inherent in multifocal IOLs. OBJECTIVES: The objective of this review was to assess the effects of multifocal IOLs, including effects on visual acuity, subjective visual satisfaction, spectacle dependence, glare and contrast sensitivity, compared to standard monofocal lenses in people undergoing cataract surgery. METHODS: Search methods: We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register, The Cochrane Library 2012, Issue 2, MEDLINE (January 1946 to March 2012, EMBASE (January 1980 to March 2012, the metaRegister of Controlled Trials (mRCT (www.controlled-trials.com, ClinicalTrials.gov (www.clinicaltrials.gov and the WHO International Clinical Trials Registry Platform (ICTRP (www.who.int/ictrp/search/en. We did not use any date or language restrictions in the electronic searches for trials. The electronic databases were last searched on 6 March 2012. We searched the reference lists of relevant articles and contacted investigators of included studies and manufacturers of multifocal IOLs for information about additional published and unpublished studies. Selection criteria: All randomised controlled trials comparing a multifocal IOL of any type with a monofocal IOL as control were included. Both unilateral and bilateral implantation trials were included. Data collection and analysis: Two authors collected data and assessed trial quality. Where possible, we pooled data from the individual studies using a random-effects model, otherwise we tabulated data. MAIN RESULTS: Sixteen completed trials

  4. Proposta de um modelo de gestão integrada da cadeia de suprimentos: aplicação no segmento de eletrodomésticos

    Directory of Open Access Journals (Sweden)

    Reinaldo Fagundes dos Santos

    2015-03-01

    Full Text Available O espectro da competitividade entre as organizações manufatureiras, numa economia cada vez mais globalizada, já não se limita ao jogo de forças entre as organizações concorrentes, mas acontece de fato entre cadeias de suprimentos. Entretanto, os atuais modelos de gestão da cadeia de suprimentos não vêm cumprindo seu papel, havendo grande disparidade entre os potenciais benefícios e a prática. O presente trabalho tem como objetivo propor um modelo de SCM e seu método de implementação, visando aumentar a capacidade de resposta ao mercado consumidor das empresas manufatureiras. O modelo proposto utiliza os conceitos da Manufatura Enxuta, da Teoria das Restrições e do modelo SCOR em um ambiente de Tecnologia da Informação e Comunicação. São aplicados também os conceitos do Triple Bottom Line na busca da sustentabilidade. A avaliação de sua eficácia é feita através de uma aplicação no segmento de eletrodomésticos, permitindo sugerir a ampliação do escopo de sua utilização.

  5. O exame de imagem do segmento anterior no diagnóstico de certeza da catarata branca intumescente Image test in the sure diagnosis of intumescent white cataract

    Directory of Open Access Journals (Sweden)

    Virgilio Centurion

    2008-10-01

    Full Text Available OBJETIVO: Identificar aspectos na ACSA (analise computadorizada do segmento anterior que levem ao diagnóstico de certeza de CBI (catarata branca intumescente. MÉTODOS: Dois grupos de olhos, com catarata branca e nigra são estudados utilizando-se os critérios clínico e laboratorial. RESULTADOS: A espessura do cristalino > 5.36mm e o seu aspecto esferiforme foram evidenciados como dados mais freqüentes na catarata branca intumescente (CBI. CONCLUSÃO: A utilização da ACSA fornece dados importantes no diagnóstico de certeza da CBI.PURPOSE: To identify aspects of the image test to arrive at the sure diagnosis of intumescent white cataract. METHODS: Two groups of eyes with white and nigra cataracts were studied using clinical and laboratorial criteria. RESULTS: The width of the lens > 5.36mm and its spherical aspect are the two data that provided us with a sure diagnosis of intumescent white cataract. CONCLUSION: The use of the image test provides data for the sure diagnosis of intumescent white cataract.

  6. Tratamento cirúrgico das lesões traumáticas do segmento médio-inferior da coluna cervical

    Directory of Open Access Journals (Sweden)

    HERCULANO MARCO ANTONIO

    2000-01-01

    Full Text Available O nível C2 é o mais frequente em lesões traumáticas da coluna cervical, sendo seguido por C5 e C6. Elas ocorrem, mais habitualmente, na terceira década de vida, com incidência decrescente na idade avançada. Como parte destas lesões está localizada nos elementos da coluna anterior, segundo a conceituação de Denis e, levado-se em consideração os estudos biomecânicos do segmento médio--inferior da coluna cervical, bem como os mecanismos que causam estas lesões, elaboramos este estudo, com o intuito de apresentar as técnicas de fusão cervical anterior, com enxerto ósseo e placas de Caspar, Morscher (CSLP e ORION(TM. Mostramos e discutimos as vantagens e desvantagens de cada tipo de fixação anterior, com base nos dados de literatura, evidenciando a melhoria no material de implante e das técnicas de fixação.

  7. Análise do fluxo informacional presente em uma empresa do segmento de serviços de valor agregado (SVA

    Directory of Open Access Journals (Sweden)

    Izabella Bauer de Assis Cunha

    Full Text Available O objetivo principal deste artigo foi demonstrar a existência e a importância do fluxo informacional entre o setor de Business Intelligence e os setores de Negócios e Produtos de uma empresa do segmento de Serviço de Valor Agregado (SVA. A principal fundamentação teórica baseou-se em modelos de identificação das necessidades, percepções e análises informacionais, processos de busca e uso da informação e representação do fluxo de informação. Foi utilizado o estudo de caso único como principal método de pesquisa. Foram realizadas entrevistas individuais em profundidade com o diretor de Pesquisa e Desenvolvimento e os representantes das áreas envolvidas da empresa foco do estudo. Como resultados alcançados, foram identificados os gaps e possíveis melhorias do atual fluxo de informação existente entre os setores analisados, e proposto um modelo "ideal", com objetivo de aumentar a eficiência operacional e analítica entre os setores.

  8. Estudo mecânico de implante para fixação do segmento lombossacro da coluna vertebral Mechanical study of implant for lumbossacral spinal fixation

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    Afrane Serdeira

    2000-09-01

    Full Text Available Foram estudados, do ponto de vista mecânico, a rigidez e os pontos críticos de um implante para fixação interna da coluna lombossacra. Aplicou-se o implante sobre um modelo de madeira simulando o segmento lombossacro da coluna. Realizamos sete ensaios de flexo-compressão, sete de rigidez axial, sete de rigidez radial e um ensaio destrutivo. Os resultados demonstraram que o implante foi eficiente e seguro para uso em seres humanos.This work consists of a mechanical analysis of the resistance and critical points of a stainless steel device for lumbossacral spinal fixation. The device was fixed into a wooden model representing the spinal lumbossacral segment. The experiment comprised seven tests of flexo-compression, seven tests of axial rigidity, seven tests of radial rigidity, and one destructive test. The critical points are the intersection of the pedicular screws threads and the attrition rate between the vise and the rod. The results demonstrated the device to be efficient and safe when used in human beings.

  9. Plan de empresa para TECO: modelo de impacto social, autosostenibilidad financiera y de minimización de la huella del e-waste en Bogotá

    OpenAIRE

    Bustamante García, Daniel

    2013-01-01

    La red TECO es una iniciativa que integra elementos ya conocidos en el mundo de la publicidad y de la gestión RAEE, en un nuevo modelo de negocio. Esto le permite competir de manera efectiva en un segmento de mercado que si bien no está saturado, requiere de cambios estructurales para poder cumplir su objetivo. El éxito del modelo de TECO radicará en la capacidad de generar su propio flujo de dinero, lo que le garantiza su auto sostenimiento, mientras minimiza la barrera del pensamiento tradi...

  10. Plan estratégico de marketing para el desarrollo del turismo arqueológico receptivo en la ruta Nasca

    OpenAIRE

    Losno Valverde, Javier; Romero Pérez, Ludwen César; Salazar Bazán, Gerardo

    2017-01-01

    xviii, 143 h. : il. ; 30 cm. En los últimos años el sector turístico se ha diversificado y evolucionado de una forma considerable con el fin de satisfacer la expectativa de un turista cada vez más exigente y especializado. Es así que actualmente dentro del segmento de turismo cultural (TC), en el Perú encontramos al turismo arqueológico (TA), que representa el 54% de participación del flujo turístico (PromPerú, 2015). Debemos resaltar que a pesar de que el Perú posee una riq...

  11. Evaluación estética del tratamiento de casos con agenesia de incisivos laterales superiores : cierre frente a apertura de espacios

    OpenAIRE

    Suárez Tuero, Cristina

    2015-01-01

    La ausencia de incisivos laterales maxilares compromete la estética de la sonrisa y la función normal debido a que afecta a las proporciones del segmento maxilar anterior. Cuando un incisivo lateral maxilar falta congénitamente se generan alteraciones en la arcada superior así como en su relación con la mandíbula, no solo por el hecho de la ausencia en si, sino porque la agenesia dental coexiste, en ocasiones, con otro tipo de cambios en la forma y tamaño del resto de la dentición. El restabl...

  12. Caracterización clínica y electrofisiológica de las alteraciones recíprocas del electrocardiograma en el infarto agudo de miocardio

    OpenAIRE

    Noriega Sanz, Francisco Javier

    2015-01-01

    La isquemia miocárdica transmural, producida por oclusión coronaria aguda, genera unos cambios en la actividad eléctrica del corazón, como consecuencia de las alteraciones metabólicas que suceden en los miocardiocitos por la falta de flujo coronario. Estos cambios se manifiestan en el electrocardiograma (ECG) como elevación del segmento ST en las derivaciones enfrentadas al área isquémica, lo que permite realizar una aproximación de la localización de la oclusión arterial coronaria. Adicional...

  13. Posterior Chamber Scleral Fixation of Intraocular Lenses in Post-Vitrectomised Aphakic Eyes.

    Science.gov (United States)

    Obeng, Francis Kwasi; Vig, Vipan Kumar; Singh, Preetam; Singh, Rajbir; Dhawan, Bodhraj; Sahajpal, Nikhil

    2017-03-01

    The best method of aphakia correction is in the bag implantation of Posterior Chamber Intraocular Lens (PCIOL). When this ideal procedure is not possible due to lack of integrity of posterior capsule or zonules, the other alternatives are broadly categorized into two: extraocular and intraocular. Whereas, the former includes contact lenses and aphakic glasses, the latter ones are further divided into anterior and posterior chamber methods. Anterior Chamber Intraocular Lenses (ACIOL) can be with or without iris claw. At the posterior chamber, fixation of the lenses can be with glue or sutures. When there is combined Pars Plana Vitrectomy (PPV) and lensectomy or if the indication of PPV is dropped nucleus or intraocular lens, a modality of aphakia correction should be devised. Posterior Chamber Scleral Fixation of Intraocular Lenses (PCSFIOL) with sutures is a preferred method because of its low complication profile. However, data on correction of aphakia after combined PPV and lensectomy is limited. To fill in this gap in knowledge, we evaluated the secondary PCSFIOL in aphakic eyes after previous PPV and lensectomy. To assess the outcome and complication profile of a large series of patients who underwent secondary PCSFIOL implantation with sutures after combined PPV and lensectomy. Records of all patients who had undergone secondary PCSFIOL implantation with sutures after combined PPV and lensectomy from 2010 to 2014 were reviewed retrospectively for visual outcomes and complications. Patients' demographic data, indication for PPV, best corrected preoperative and postoperative visual acuities, complications of surgery, and indications of PCSFIOL and length of follow up were collected and analyzed. A total of 148 eyes of 148 patients (127 males and 21 females) were identified. Mean age at surgery was 32.5±8 years (range 2.5-73 years) with a mean follow up 23±14 months (range 3-114 months). A total of 95.27%, 2.70% and 2.02% of patients had improvement

  14. Posterior Chamber Scleral Fixation of Intraocular Lenses in Post-Vitrectomised Aphakic Eyes

    Science.gov (United States)

    Vig, Vipan Kumar; Singh, Preetam; Singh, Rajbir; Dhawan, Bodhraj; Sahajpal, Nikhil

    2017-01-01

    Introduction The best method of aphakia correction is in the bag implantation of Posterior Chamber Intraocular Lens (PCIOL). When this ideal procedure is not possible due to lack of integrity of posterior capsule or zonules, the other alternatives are broadly categorized into two: extraocular and intraocular. Whereas, the former includes contact lenses and aphakic glasses, the latter ones are further divided into anterior and posterior chamber methods. Anterior Chamber Intraocular Lenses (ACIOL) can be with or without iris claw. At the posterior chamber, fixation of the lenses can be with glue or sutures. When there is combined Pars Plana Vitrectomy (PPV) and lensectomy or if the indication of PPV is dropped nucleus or intraocular lens, a modality of aphakia correction should be devised. Posterior Chamber Scleral Fixation of Intraocular Lenses (PCSFIOL) with sutures is a preferred method because of its low complication profile. However, data on correction of aphakia after combined PPV and lensectomy is limited. To fill in this gap in knowledge, we evaluated the secondary PCSFIOL in aphakic eyes after previous PPV and lensectomy. Aim To assess the outcome and complication profile of a large series of patients who underwent secondary PCSFIOL implantation with sutures after combined PPV and lensectomy. Materials and Methods Records of all patients who had undergone secondary PCSFIOL implantation with sutures after combined PPV and lensectomy from 2010 to 2014 were reviewed retrospectively for visual outcomes and complications. Patients’ demographic data, indication for PPV, best corrected preoperative and postoperative visual acuities, complications of surgery, and indications of PCSFIOL and length of follow up were collected and analyzed. Results A total of 148 eyes of 148 patients (127 males and 21 females) were identified. Mean age at surgery was 32.5±8 years (range 2.5-73 years) with a mean follow up 23±14 months (range 3-114 months). A total of 95.27%, 2

  15. Comparison of the Retinal Straylight in Pseudophakic Eyes with PMMA, Hydrophobic Acrylic, and Hydrophilic Acrylic Spherical Intraocular Lens

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    Ya-wen Guo

    2014-01-01

    Full Text Available Purpose. To investigate the intraocular straylight value after cataract surgery. Methods. In this study, 76 eyes from 62 patients were subdivided into three groups. A hydrophobic acrylic, a hydrophilic acrylic, and a PMMA IOL were respectively, implanted in 24 eyes, 28 eyes, and 24 eyes. Straylight was measured using C-Quant at 1 week and 1 month postoperatively in natural and dilated pupils. Results. The hydrophilic acrylic IOLs showed significantly lower straylight values than those of the hydrophobic acrylic IOLs in dilated pupils at 1 week and 1 month after surgery (P0.05. Moreover, no significant difference was found in straylight between natural and dilated pupils in each group at 1 week and 1 month postoperatively (P>0.05. Conclusions. Although the hydrophobic acrylic IOL induced more intraocular straylight, straylight differences among the 3 IOLs were minimal. Pupil size showed no effect on intraocular straylight; the intraocular straylight was stable 1 week after surgery.

  16. [The effect of crystalline lens extraction on intraocular pressure in patients with primary open-angle glaucoma].

    Science.gov (United States)

    Macarie, S; Macarie, Daniela

    2013-01-01

    This issue presents the results of a study on patients with cataract and primary open angle glaucoma who suffered lens extraction for cataract. We analise the effects of the lens extraction on the level of intraocular pressure at this patients.

  17. INTRAOCULAR TRANSMISSIBLE VENEREAL TUMOR IN A DOG TUMOR VENÉREO TRANSMISSÍVEL INTRA-OCULAR EM CÃO

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    Geórgia Nadalini Rodrigues

    2001-02-01

    Full Text Available Canine transmissible venereal tumor (TVT is a round cell neoplasm occurring on the external genital mucosa of male and female dogs. Transmission is by cell implantation during coitus, licking, or other interaction between an affected dog and a susceptible host. Metastasis of the tumor rarely occurs. This report describes an unusual presentation of TVT with intraocular involvement and inguinal lymph nodes metastasis. The subject was a six-year-old, intact, male, Brazilian Terrier dog with a history of abnormal masses in the right eye, penis and several subcutaneous nodules in the inguinal area. Histopathological examination of the eye specimens as well as cytologic examination of penile mass and subcutaneous nodules revealed similar findings. The examination revealed round cells containing a large nuclei with prominent, central located nucleoli and a pale cytoplasm containing few small, clear round vacuoles. Histologically, the subcutaneous nodules in the inguinal area were lymph nodes. The diagnosis of TVT with intraocular involvement and lymph nodes metastasis was based on clinical, cytologic and histopathologic findings.Tumor venéreo transmissível (TVT é uma neoplasia de células redondas que acomete a mucosa genital externa de cães, machos e fêmeas. A transmissão decorre da implantação de células tumorais durante o coito, brigas ou interações entre animais portadores e susceptíveis. Existem relatos referindo-se a localizações atípicas do TVT, mas metástases raramente ocorrem. O presente relato descreve um caso incomum de TVT, com acometimento intra-ocular e metástases nos linfonodos ingüinais, num cão Terrier Brasileiro, com seis anos de idade. O animal apresentava massas anormais de tecido no olho direito, extremidade do pênis e aumento de volume de linfonodos da região ingüinal. A histopatologia do globo ocular e as citologias da massa peniana e dos nódulos subcutâneos evidenciaram aspectos citológicos semelhantes

  18. ANÁLISIS DEL VALOR DE MARCA DE LAS ENTIDADES FINANCIERAS: EL EFECTO HALO Y EL MODELO DE ELECCIÓN DISCRETA

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    García de los Salmones Sánchez, M.M.

    2009-01-01

    Full Text Available El presente trabajo trata de cuantificar el valor de marca y el posicionamiento de las entidades financieras en dos mercados diferentes: consumidores finales y microempresas. Así mismo, se busca identificar las dimensiones de imagen de mayor peso a la hora de elegir a una entidad como la de mejor valoración global. A través del modelo de elección discreta y del análisis del efecto halo ,se comprueba la importancia del trato personal al cliente como la variable de mayor peso en la elección de marca. Además, se observa la mayor intensidad del efecto halo para las cajas de ahorros en el caso de los consumidores particulares. Sin embargo, en el segmento de microempresas, el valor de marca es superior para los bancos.

  19. Acyclovir-resistant herpes simplex virus type 1 in intra-ocular fluid samples of herpetic uveitis patients.

    Science.gov (United States)

    van Velzen, Monique; Missotten, Tom; van Loenen, Freek B; Meesters, Roland J W; Luider, Theo M; Baarsma, G Seerp; Osterhaus, Albert D M E; Verjans, Georges M G M

    2013-07-01

    Acyclovir (ACV) is the antiviral drug of choice to treat patients with herpes simplex virus type 1 (HSV-1) uveitis. The prevalence of intra-ocular ACV-resistant (ACV(R)) HSV-1 in herpetic uveitis is unknown and may have clinical consequences. In addition to its predictive value on ACV susceptibility, the polymorphic HSV-1 thymidine kinase (TK) gene facilitates differentiation between HSV-1 strains. The objective of this study was to determine the genetic composition and ACV susceptibility of the causative virus in intra-ocular fluid samples (IOF) of HSV-1 uveitis patients. The intra-ocular HSV-1 pool from 11 HSV-1 uveitis patients was determined by sequencing IOF-derived viral TK genes. The ACV susceptibility profile of the cloned intra-ocular TK variants was defined by mass spectrometry. In addition, the ganciclovir (GCV) susceptibility of the ACV(R) HSV-1 TK variants was defined. Intra-ocular fluid samples of HSV-1 uveitis patients contain HSV-1 quasispecies, principally consisting of one major and multiple genetically related minor patient-specific TK variants. Four of 10 patients analyzed had an intra-ocular ACV(R) HSV-1 of which 3 were cross-resistant to GCV. The ACV(R) profile of intra-ocular HSV-1 did not correlate with symptomatic ACV treatment. Affected eyes of HSV-1 uveitis patients are commonly infected with a patient-specific HSV-1 quasispecies, including one major and multiple genetically related minor variants. A relatively high prevalence of intra-ocular ACV(R) HSV-1, mainly ACV/GCV cross-resistant viruses, was detected in HSV-1 uveitis patients. Copyright © 2013 Elsevier B.V. All rights reserved.

  20. Unusually very late-onset new growth of intraocular retinoblastoma: A case report and review of literature

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    Yeshigeta Gelaw

    2017-04-01

    Conclusions and importance: Despite initial satisfactory treatment and complete regression of the tumor, very late-onset new growth of intraocular retinoblastoma can occur. Hence, life-long follow-up in all patients with retinoblastoma is warranted, given the risk for new tumor formation even later in life. To our knowledge, this is the first report of new growth of intraocular retinoblastoma after regression for more than a decade.

  1. Implante de lente intraocular en niños como solución a los problemas sociales de la ceguera por catarata congénita Intraocular lens implants for children as a solution to social problems caused by blindness from congenital cataract

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    Rosa María Naranjo Fernández

    2011-12-01

    Full Text Available Se estima en alrededor de 1,5 millones el número de niños con baja visión o ciegos legales, alrededor del mundo, con una prevalencia de 1 a 4 por cada 10 000 niños en los países industrializados y de 5 a 15 en los países en vías de desarrollo. La prevalencia de la ceguera infantil en América Latina es de 0,6 %, lo cual representa 900 niños por cada millón de habitantes que necesitan asistencia para visión baja. La prevalencia de ceguera por catarata congénita puede estar entre 1 y 4 por cada 10 000 niños en países subdesarrollados y entre 0,1 a 0,4 en países industrializados. En Cuba con una población de 2,1 millones de habitantes menores de 15 años la catarata congénita es considerada la segunda causa de ceguera infantil. En los últimos 20 años ha revolucionado completamente el tratamiento quirúrgico de la catarata en niños, por el desarrollo alcanzado en el perfeccionamiento de las técnicas quirúrgicas. En nuestro país la cirugía de catarata pediátrica con implante de lente intraocular comenzó en el año 1990, posterior a la inauguración del centro de Microcirugía Ocular en el año 1988. Queda demostrada la importancia de la cirugía de catarata pediátrica con implante de lente intraocular, como una solución a los problemas sociales ocasionados por el déficit visual del paciente no tratado oportunamente, con la aplicación de tecnología moderna se logra mejorar la calidad de vida de los niños, tanto social como educacional, incorporándolos de una forma activa a la sociedad.It is estimated that around 1,5 million children with low vision or legally blind exist worldwide, with a prevalence of 1 to 4 per 10 000 children in the industrialized countries and of 5 to 15 in the developing countries. The prevalence rate of the infantile blindness in Latin America is 0,6 %, which represents 900 children per one million inhabitants who need medical assistance due to low vision. The prevalence of blindness due to

  2. Aderência in vitro do Staphylococcus epidermidis e da Pseudomonas alcaligenes em lentes intra-oculares In vitro adherence of Staphylococcus epidermidis and Pseudomonas alcaligenes to intraocular lenses

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    Patrícia Ioschpe Gus

    2006-06-01

    Full Text Available OBJETIVO: Quantificar e comparar a aderência in vitro das bactérias Staphylococcus epidermidis e Pseudomonas alcaligenes em diferentes tipos de lentes intra-oculares (LIOs. MÉTODOS: Quatorze lentes intra-oculares foram usadas no experimento. Quatro de polimetilmetacrilato (PMMA, quatro de silicone, quatro de hidrogel e duas de acrílico. Oito lentes intra-oculares foram colocadas em oito tubos de ensaio contendo 4 ml de suspensão de Pseudomonas alcaligenes, e seis lentes intra-oculares foram colocadas em seis tubos de ensaio contendo 4 ml de suspensão de Staphylococcus epidermidis. A concentração do caldo utilizada para o teste de aderência foi de 10(8 unidades formadoras de colônias por mililitro (CFU/mL que corresponde a 0,5 na escala de McFarland. As lentes foram incubadas a 37° por duas horas. Após, foram removidas dos caldos e enxaguadas em água destilada estéril por duas vezes. As lentes foram cultivadas em placas de ágar-sangue a 35-37° e evaliadas a cada 24h por um período de 72h. Nas amostras que tiveram crescimento bacteriano, foram contadas as colônias utilizando os métodos convencionais de laboratório. Todos os ensaios foram executados em duplicata. RESULTADOS: A aderência do Staphylococcus epidermidis nas lentes de PMMA foi menor se comparada com as de silicone e de hidrogel. A aderência daPseudomonas alcaligenes nas lentes de hidrogel foi menor se comparada com as de silicone, PMMA e acrílico. CONCLUSÃO: Os resultados sugerem que a aderência do Staphylococcus epidermidis e da Pseudomonas alcaligenes nas lentes intra-oculares é influenciada pelo tipo de material da lente e pela espécie do microorganismo. A aderência bacteriana pode ter papel importante na patogenicidade da endoftalmite pós-cirurgia de catarata.PURPOSE: To quantify and compare the in vitro adherence of Staphylococcus epidermidis and Pseudomonas alcaligenes to different intraocular lenses (IOLs. METHODS: Fourteen intraocular lenses were

  3. Segments of competition in south brazilian wineries Segmentos de competição em vinícolas do sul do Brasil

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    Marcelo Miele

    2007-06-01

    Full Text Available The international restructuring process in the beverage sector reached the winemaking business in the 1990s, changing its panorama. Increasing competitive pressure is a characteristic of this period with significant impact in regions such as the countries belonging to the Mercosul block. To support firm strategies and public policies, the goal of this study was to identify the competition segments in winemaking in Rio Grande do Sul, the southern state of Brazil, and in a specific form to propose a typology of wineries based on the Industrial Organization literature. The data used are from the State Wineries Data Bank of Rio Grande do Sul, which were submitted to multivariate statistical analysis, integrating a cluster and principal components analysis in a group of 381 observations. The results showed the existence of two factors, one related to scale and diversification, and the other related to the quality of the products and of the raw material. From these factors, six groups of wineries were identified that can be named segments of competition in winemaking. Group 1 is characterized by quality and specialization; group 2, by a large production scale and diversification; group 3, by a low added value; group 4, by a micro production scale; and groups 5 and 6, by a low added value, small scale, and specialization.O processo de reestruturação internacional no setor de bebidas atingiu a vitivinicultura na década de 1990, alterando o seu panorama. Característico a esse período é o aumento da pressão competitiva, com impactos significativos em regiões como a dos países membros do Mercosul. Para apoiar as estratégias empresariais e as políticas públicas, o objetivo deste estudo foi identificar os segmentos de concorrência da vitivinicultura do Rio Grande do Sul e, de forma específica, propor uma tipologia das vinícolas gaúchas com base na literatura da Organização Industrial. Utilizaram-se os dados do Cadastro Vinícola do Rio

  4. Comparison of Nd: YAG capsulotomy rate between 1-piece and 3-piece acrylic intraocular lenses: A STROBE-compliant article.

    Science.gov (United States)

    Kim, Sun Young; Chung, Young Kwon; Shin, Hye Young; Lee, Mee Yon; Lee, Young-Chun; Kim, Su-Young

    2017-07-01

    The aim of the study is to compare Nd:YAG capsulotomy rate between acrylic 1- and 3-piece intraocular lenses. Among 924 eyes of 762 patients who received cataract surgery, we selected the 303 patients (404 eyes) implanted with an SN60WF 1-piece intraocular lens (Alcon, Fort Worth, TX) or a YA-60BBR 3-piece intraocular lens (Hoya Co., Tokyo, Japan). For intraindividual comparison, we enrolled the 17 patients implanted with an SN60WF in 1 eye and a YA-60BBR in the contralateral eye. We compared Nd:YAG capsulotomy rate between acrylic 1- and 3-piece intraocular lenses 24 months after the operation. Of the 404 eyes in this study, Nd:YAG capsulotomy was performed in 20 of 268 eyes (7.5%) in the SN60WF 1-piece intraocular lens group and 24 of 136 eyes (17.6%) in the YA-60BBR 3-piece intraocular lens group; the difference was statistically significant (P = .002). Among the 17 patients (34 eyes) who were implanted with 2 different inraocular lenses, Nd:YAG capsulotomy was performed in only 2 eyes (12%) in the SN60WF group and 9 eyes (53%) in the YA-60BBR group; the difference was statistically significant (P = .020).The authors found a significantly greater incidence of Nd:YAG capsulotomy in eyes who received 3-piece lenses compared with those who received 1-piece lenses.

  5. Paradigmas das práticas de gestão ambiental no segmento de produção de refeições no Brasil

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    Virgílio José Strasburg

    Full Text Available RESUMO Os processos relacionados com a produção de refeições para os consumidores são causadores de impactos para o meio ambiente. Este trabalho teve como objetivo identificar quais são as práticas de restaurantes brasileiros relacionadas com a temática da gestão ambiental e da sustentabilidade. Trata-se de um estudo de revisão sistemática de publicações no período de 2000 a 2015. Entre os resultados encontrados, destacam-se a geração de resíduos de alimentos no processo de produção e consumo das refeições, além de investigações sobre acondicionamento, reciclagem e destinação desses resíduos. São apresentadas também as temáticas de utilização de recursos (água e energia e um panorama sobre a avaliação dos aspectos ambientais por meio da prática de certificação de restaurantes comerciais com selos de sustentabilidade. Estudos avaliativos dessa natureza são importantes para contribuir para o diagnóstico da realidade no segmento de produção de refeições e também para fomentar investigações futuras que apontem para a redução dos impactos ambientais nessa atividade.

  6. Logística reversa no segmento de resíduos de garrafa de vidro: estudo de caso na empresa Cacos de Vidro Mazzeto

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    Jenifer Dallaqua Sabião

    2016-10-01

    Full Text Available O vidro é um produto 100% reciclável e de menor custo de produção, porém o descarte inadequado faz com que represente enorme problema para o meio ambiente e a sociedade. Seus elementos constitutivos permanecem os mesmos e em função do avanço da tecnologia houve significativo progresso na forma de manuseio, permitindo assim, maior variedade para o seu uso. Sendo assim, essa investigação, fez uso da literatura relacionada ao tema, bem como, de visitas técnicas e de entrevistas com profissionais da empresa Comércio de Cacos de Vidro Mazzetto, no intuito de avaliar qual é o real papel dessa empresa no processo de Logística Reversa de garrafas de vidro. A empresa investigada realiza a captação do vidro oriundo das garrafas adquiridas de cooperativas locais e grandes empresas, visando posteriormente vender como matéria-prima para a indústria vidreira. A pesquisa consiste ainda na apuração de dados, a respeito do processo de reciclagem do vidro, bem como em um balanço comparativo acerca das receitas e custos da empresa nos anos de 2014 e 2016. Diante desse cenário, o presente projeto objetiva analisar como ocorre a integração da empresa investigada, dentro do processo de Logística Reversa pós-Consumo aplicado ao segmento de garrafas de vidro.

  7. SISTEMA DE INFORMAÇÕES GEOGRÁFICAS NO APOIO AO GERENCIAMENTO DE OBSTÁCULOS À SUPERFÍCIE DE SEGMENTO VISUAL

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    FÁBIO ANDERSON BATISTA DOS SANTOS

    Full Text Available A segurança e a regularidade das operações em um aeroporto são influenciadas pelo uso do solo em seu entorno. De forma a preservar a segurança das operações de pouso por instrumentos nos aeroportos, a Organização Internacional de Aviação Civil instituiu uma superfície imaginária denominada Superfície de Segmento Visual (VSS. Qualquer objeto, natural ou artificial, que se estenda acima dessa superfície é considerado obstáculo. A existência de obstáculos pode gerar uma série de restrições, como o cancelamento do procedimento de aproximação por instrumento. O objetivo deste trabalho foi desenvolver uma metodologia para utilização de Sistema de Informações Geográfica (SIG no apoio ao gerenciamento de obstáculos à VSS. Como estudo de caso, foi selecionadoo Aeroporto de Campo de Marte, em São Paulo, no qual a existência de obstáculos pode inviabilizar a implantação de procedimentos de aproximação por instrumentos. Foram utilizadas duas ferramentas complementares, uma ferramenta de SIG desktop e uma ferramenta de SIGWeb. A aplicação em SIG mostrou-se eficaz na análise dos obstáculos, mesmo sem utilizar um pacote de ferramentas para análise 3D. A aplicação foi suficiente ao integrar análise espacial em duas dimensões com uma consulta baseada em conceitos de geometria analítica.

  8. POTENCIAL ECONÔMICO DOS PRINCIPAIS SEGMENTOS DA CADEIA PRODUTIVA DO GIRASSOL NAS REGIÕES VALE DO RIO PARDO E VALE DO TAQUARI, RS

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    Jorge L. Amaral de Moraes

    2013-01-01

    Full Text Available O território formado pelas regiões Vale do Rio Pardo e Vale do Taquari (RS aproveitou a oportunidade do mercado externo e as potencialidades de seus recursos, como o grande contingente de agricultores familiares, para expandir a produção de tabaco. As instituições locais buscam identificar atividades rentáveis e implementar uma estrutura de diversificação da economia agrícola da região. Como resultado dessa busca por alternativas produtivas agroalimentares e agroindustriais, a cadeia produtiva e os produtos derivados do girassol (grãos, farelo, óleo e biodiesel aparecem como uma alternativa de diversificação produtiva a ser analisada. Este texto apresenta o resultado de uma análise econômica do potencial da cadeia produtiva do girassol como alternativa dinamizadora do desenvolvimento do território. Foi realizada uma análise de rentabilidade e uma projeção de expansão de segmentos da cadeia produtiva do girassol, como a produção e a comercialização do grão, óleo, torta e do biodiesel de girassol e seus potenciais efeitos sobre a demanda nos mercados de matéria-primas agroindustriais. Considerando os atuais preços de mercado, verificou-se a inviabilidade da utilização do óleo de girassol para a produção de biodiesel.

  9. O impacto do suporte oferecido pelos franqueadores no desempenho dos franqueados: um estudo sobre o segmento de educação do Brasil

    Directory of Open Access Journals (Sweden)

    Daniel Saldanha Guedes

    2010-08-01

    Full Text Available Qual é o impacto do suporte oferecido pelos franqueadores no desempenho dos franqueados?E como se comporta ao longo do período de vida do contrato? Para responder estas questões realizou-se um estudo quantitativo exploratório que possibilitou a identificação da relação entre suporte e desempenho das franquias do segmento de educação no Brasil e seu comportamento em franquias com diferentes tempos de operação. Os resultados demonstram: (1 que existe uma forte correlação entre a percepção da qualidade do suporte e a percepção de desempenho, ou seja, na opinião dos respondentes quanto melhor for o suporte oferecido pelos franqueadores, melhor tenderá a ser o desempenho de suas franquias; (2 que franqueados com mais tempo de operação (acima de 5 anos tendem a apresentar uma percepção de melhor suporte comparativamente aos franqueados de menor tempo de operação; e (3 que dentre todas as variáveis de suporte, a confiança inspirada pelo franqueador é a característica que mais impacta nos resultados e no conseqüente desempenho dos franqueados. As conclusões obtidas poderão auxiliar empresas franqueadoras no desenho de suas estratégias e no direcionamento de suas ações de suporte ao franqueado, bem como nos investimentos que esta área exige. Poderão ainda servir de plataforma a futuros estudos no mundo acadêmico.

  10. Prevención y tratamiento actual del glaucoma

    Directory of Open Access Journals (Sweden)

    DR. P. José Manuel Díaz

    2010-11-01

    Full Text Available El glaucoma es la principal causa de ceguera no reversible en el mundo, afectando al 2% de la población. Actualmente se considera una neuropatía óptica, donde la presión intraocular juega un rol fundamental en la patogenia y las características del daño óptico producido. Con el tratamiento actual, se busca prevenir el daño en la estructura del nervio óptico, para preservar el campo visual, persiguiendo mantener la calidad de vida del paciente. Existen nuevos métodos imaginológicos que junto al examen clínico y campo visual, predicen daño y avance de enfermedad. Se incluyen en la comprensión de la patología la apoptosis y el concepto de neuroprotección. Nuevos fármacos buscan mantener una adecuada reducción en la presión intraocular sin fluctuaciones, evitando efectos adversos y mejorando la adherencia al tratamiento. Nuevas herramientas terapéuticas como la trabeculoplastía selectiva láser y nuevas cirugías como el implante de tubos de drenaje, aumentan las posibilidades de evitar la ceguera por glaucoma.

  11. Tratamiento del astigmatismo moderado en pacientes con cataratas

    OpenAIRE

    Mateo Gabás, Javier; Ascaso Puyuelo, Francisco Javier; Cristóbal Bescós, José Ángel

    2013-01-01

    El objetivo principal de esta tesis doctoral es la comparación de los resultados obtenidos mediante dos técnicas quirúrgicas en el tratamiento del astigmatismo corneal moderado en pacientes con cataratas. La primera técnica quirúrgica es la facoemulsificación con incisiones corneales perforantes enfrentadas en el meridiano más curvo de la córnea, con implante de una lente intraocular con corrección esférica en saco capsular. La segunda técnica consiste en la facoemulsificación con implante de...

  12. Reproducibility of postural changes in intraocular pressure with the Tono-Pen and Pulsair tonometers.

    Science.gov (United States)

    Wilson, M R; Baker, R S; Mohammadi, P; Wheeler, N C; Lee, D A; Scott, C

    1993-10-15

    Reproducibility of measurements of postural changes in intraocular pressure was determined by using the Tono-Pen (Mentor O & O, Inc., Norwell, Massachusetts) and Pulsair (Keeler Instruments, Inc., Broomhall, Pennsylvania) tonometers. Thirty subjects had three repeated sitting and reclining measurements performed on three separate visit days. Reproducibility coefficients of 3.3% for the Tono-Pen and 6.3% for the Pulsair were obtained for the within-visit postural change measurements. Across-visit reproducibility coefficients were 7.9% and 26.2% for the Tono-Pen and Pulsair, respectively. The estimated standard deviations for both the within-visit and across-visit postural change measurements were high for both instruments. These results indicate poor reproducibility of measurements of postural changes in intraocular pressure.

  13. Chiron Vision files FDA application to market intraocular implant for CMV retinitis. Food and Drug Administration.

    Science.gov (United States)

    1995-07-01

    Chiron Corporation and Hoffman-LaRoche announced a filing of a New Drug Application with the Food and Drug Administration (FDA) to market Vitrasert, its intraocular implant which delivers ganciclovir directly to the eye for treatment of CMV retinitis. Clinical trials show that Vitrasert offers a clinical improvement versus intravenous ganciclovir in further delaying progression of CMV retinitis in the treated eye. One study reported that the median time to progression of CMV retinitis was 186 days for eyes receiving Vitrasert compared to 72 days for eyes receiving intravenous ganciclovir therapy. Chiron's intraocular implant contains ganciclovir embedded in a polymer-based system that slowly releases the drug into the eye for up to eight months. Two additional trials are underway. For further information contact the Professional Services Group at Chiron Corporation at (800) 244-7668, select 2.

  14. Delivery of Intraocular Triamcinolone Acetonide in the Treatment of Macular Edema

    Directory of Open Access Journals (Sweden)

    Brent Siesky

    2012-03-01

    Full Text Available Macular edema (ME is one of the eventual outcomes of various intraocular and systemic pathologies. The pathogenesis for ME is not yet entirely understood; however, some of the common risk factors for its development have been identified. While this investigation will not discuss the numerous etiologies of ME in detail, it appraises the two most widely studied delivery modalities of intraocular corticosteroids in the treatment of ME—intravitreal injection (IVI and sub-Tenon’s infusion (STI. A thorough review of the medical literature was conducted to identify the efficacy and safety of IVI and STI, specifically for the administration of triamcinolone acetonide (TA, in the setting of ME in an attempt to elucidate a preferred steroid delivery modality for treatment of ME.

  15. Implantation of iris-claw Artisan intraocular lens for aphakia in Fuchs′ heterochromic iridocyclitis

    Directory of Open Access Journals (Sweden)

    Ahmad Kheirkhah

    2014-01-01

    Full Text Available Implantation of iris-claw Artisan intraocular lens (IOL is a surgical option for correction of aphakia; however, these IOLs have not been used in eyes with uveitis including Fuchs′ heterochromic iridocyclitis (FHI due to possible risk of severe postoperative intraocular inflammation. In the case reported here, we secondarily implanted an Artisan IOL in a 28-year-old man with FHI who had aphakia with no capsular support due to a previous complicated cataract surgery. Enclavation was easily performed and no intraoperative complication was noted. Postoperative course was uneventful with no significant anterior chamber inflammation during 12 months of follow-up. Although there were few deposits on the IOL surface, the patient achieved a best-corrected visual acuity of 20/20 without developing glaucoma or other complications. Therefore, Artisan IOL may be considered for correction of aphakia in patients with FHI. However, studies on large number of patients are required to evaluate safety of the procedure.

  16. Intraocular pressure variation following retrobulbar anaesthesia among the different sex, age and ethnic groups in Malaysia.

    Science.gov (United States)

    Lee, F N; Kong, V Y; Lee, G P; Ho, K H; Choon, S C; Hoh, H B

    1999-12-01

    A total of 114 patients (48 Chinese, 34 Malay and 32 Indian) undergoing extracapsular cataract extraction (ECCE) with intraocular lens implantation, were enrolled. All were given 3 ml of local anaesthetic (combination of equal amounts of lignocaine 2% and bupivacaine 0.5%) using retrobulbar technique. Intraocular pressure (IOP) was measured at different time intervals; before, immediately after and 5 minutes after injection with Honan balloon compression. Mean IOP increased by 5.0 mmHg immediately after injection (p age groups, Chinese patients demonstrated the highest IOP rise following retrobulbar anaesthesia. This is the first study to demonstrate the influence of race in the IOP response with Chinese subjects having the highest IOP rise.

  17. [Importance of asferic treatment of intraocular lenses in contrast sensitivity of the human eye].

    Science.gov (United States)

    Calţaru, Dana Cristina; Pop, Mihai

    2014-01-01

    Clinical study which follows the influence of asphericity of intraocular lenses on an important parameter of quality of vision in operated cataract patients - contrast sensibility. This is a pilot, prospective study with 131 eyes of 124 patients, which had cataract surgery by phacoemulsification between 2011-2012. All operations were done by the same surgeon. EXCLUSION CRITERIAS WERE: VA ( 0.7; postop refraction >0.75 D sf. or 0.75 D cyl, corneal diseases, optic nerv or retinal pathologies, atypical surgery, pupil diameter 3 mm. Postoperative control was done at six weeks and included : AV, optical correction, contrast sensibility testing, intraocular pressure, posterior pol exam. Contrast sensibility testing was done using a LCD device, in fotopic condition, CC-100 TOPCON. Contrast sensibility graphics were compared between spheric and aspheric lenses for Zeiss, AMO, Bausch&Lomb, Alcon. There were no statistically significant differences between aspherical lenses. Also, there were no differences for the same manufacturer between spherical and aspherical lenses.

  18. UV laser ablation of intraocular lenses: SEM and AFM microscopy examination of the biomaterial surface

    International Nuclear Information System (INIS)

    Spyratou, E.; Asproudis, I.; Tsoutsi, D.; Bacharis, C.; Moutsouris, K.; Makropoulou, M.; Serafetinides, A.A.

    2010-01-01

    Several new materials and patterns are studied for the formation and etching of intraocular lenses (IOLs), in order to improve their optical properties, to reduce the diffractive aberrations and to decrease the incidence of posterior capsular opacification. The aim of this study is to investigate the use of UV (λ = 266 nm) laser pulses to ablate the intraocular lenses materials, and thus to provide an alternative to conventional surface shaping techniques for IOLs fabrication. Ablation experiments were conducted using various polymer substrates of hydrophobic acrylic IOLs and PMMA IOLs. We investigated the ablation efficiency and the morphology of the ablated area by imaging the surface modification with atomic force microscopy (AFM) and scanning electron microscopy (SEM). The morphological appearance of IOL samples reveals the effect of a photochemical and photothermal ablation mechanism.

  19. Single suture iris-to-capsulorhexis fixation for in-the-bag intraocular lens subluxation.

    Science.gov (United States)

    Siegel, Michael J; Condon, Garry P

    2015-11-01

    We present a simplified modification to a technique for early or mild in-the-bag subluxation that avoids conjunctival and scleral incisions and minimizes intraocular manipulation. While the capsulorhexis edge is grasped with an intraocular forceps to stabilize the IOL-capsular bag complex, a 10-0 polypropylene suture on a long curved needle is used to secure the fibrotic superior capsulorhexis edge to the midperipheral iris at 12 o'clock using a combination of a modified McCannel suture and a Siepser sliding knot. Dr. Condon receives speaker and consultant fees from Alcon Surgical, Inc., Allergan, Inc., and Microsurgical Technology. Although the Microsurgical Technology Condon snare instrument is named after him, Dr. Condon reports no patents, fees, or payments related to it. Dr. Siegel has no financial or proprietary interest in any material or method mentioned. Copyright © 2015. Published by Elsevier Inc.

  20. Long-term results of intraocular lens implantation in pediatric patients.

    Science.gov (United States)

    Sinskey, R M; Stoppel, J O; Amin, P

    1993-05-01

    Between 1980 and 1990, 42 eyes of 34 patients (age range: 18 months to 18 years) were implanted with an intraocular lens, with 29 being primary implantations and 13 secondary. The primary implantation group comprised patients with congenital, developmental, and traumatic cataracts. Patients in the developmental and traumatic cataract groups achieved the best visual acuity. Those with congenital cataracts had the poorest visual outcome. Follow-up ranged from a minimum of three months to more than ten years. Overall the patients demonstrated an improvement in visual acuity and the psychological advantage of enhanced visual function without spectacles or contact lenses. We conclude that with proper case selection and a controlled, skilled surgical approach, the use of an intraocular lens for visual rehabilitation in the pediatric age group is a feasible approach.

  1. Intraocular Lens Power Calculation after Refractive Surgery: A Comparative Analysis of Accuracy and Predictability

    OpenAIRE

    Kang, Byeong Soo; Han, Jeong Mo; Oh, Joo Youn; Kim, Mee Kum; Wee, Won Ryang

    2017-01-01

    Purpose To compare the accuracy of intraocular lens (IOL) power calculation using conventional regression formulae or the American Society of Cataract and Refractive Surgery (ASCRS) IOL power calculator for previous corneal refractive surgery. Methods We retrospectively reviewed 96 eyes from 68 patients that had undergone cataract surgery after keratorefractive surgeries. We calculated the formula with two approaches: IOL powers using the ASCRS IOL power calculator and IOL powers using conven...

  2. Effects of intraocular lenses with different diopters on chromatic aberrations in human eye models

    OpenAIRE

    Song, Hui; Yuan, Xiaoyong; Tang, Xin

    2016-01-01

    Background In this study, the effects of intraocular lenses (IOLs) with different diopters (D) on chromatic aberration were investigated in human eye models, and the influences of the central thickness of IOLs on chromatic aberration were compared. Methods A Liou-Brennan-based IOL eye model was constructed using ZEMAX optical design software. Spherical IOLs with different diopters (AR40e, AMO Company, USA) were implanted; modulation transfer function (MTF) values at 3?mm of pupil diameter and...

  3. Intraocular Telescopic System Design: Optical and Visual Simulation in a Human Eye Model

    OpenAIRE

    Zoulinakis, Georgios; Ferrer-Blasco, Teresa

    2017-01-01

    Purpose. To design an intraocular telescopic system (ITS) for magnifying retinal image and to simulate its optical and visual performance after implantation in a human eye model. Methods. Design and simulation were carried out with a ray-tracing and optical design software. Two different ITS were designed, and their visual performance was simulated using the Liou-Brennan eye model. The difference between the ITS was their lenses’ placement in the eye model and their powers. Ray tracing in bot...

  4. Intra-ocular medulloepithelioma as a masquerade for PHPV and Panophthalmitis: a Diagnostic Dilemma

    Directory of Open Access Journals (Sweden)

    Neelam Pushker

    2017-04-01

    Full Text Available A previously diagnosed child of persistent hyperplastic primary vitreous (PHPV with painless blind eye remained clinically silent for about 3 years follow-up. The child suddenly presented as a case of orbital cellulitis and panopthalmitis with meningitis. No definite mass lesion was detected on ultrasonography, magnetic resonance imaging (MRI and positron emission tomography (PET scan. Histopathology of the enucleated eye revealed intra-ocular medulloepithelioma as the culprit of sterile panophthalmitis and orbital inflammation.

  5. Use of a new intra-ocular spectral domain optical coherence tomography in vitreoretinal surgery.

    Science.gov (United States)

    Mura, Marco; Iannetta, Danilo; Nasini, Francesco; Barca, Francesco; Peiretti, Enrico; Engelbrecht, Leonore; de Smet, Marc D; Verbraak, Frank

    2016-05-01

    To describe the use of a novel intra-ocular side-scanning probe enabling the acquisition of spectral-domain optical coherence tomography (SD-OCT) images during surgery in a series of patients with complex forms of retinal detachment. A 23-gauge, side-scanning SD-OCT probe (C7 System; LightLab Imaging, Inc/St Jude Medical, St. Paul, MN, USA) in a 20-gauge catheter, was used to acquire the intra-operative OCT images in seven patients with vitreoretinal diseases. Twenty-five gauge pars plana vitrectomy (PPV) was performed in every patient in a standard fashion. After enlarging the temporal sclerotomy to a 20-gauge port, all the patients were scanned with intra-ocular side-scanning SD-OCT, during different steps of the surgery based on surgeon needs. Scans were recorded real time and directly evaluated on a screen during surgery. Optical coherence tomography (OCT) scans were judged beneficial when they would recognize structures otherwise not seen on biomicroscopy. The intra-ocular SD-OCT has been helpful in acquiring extra information during vitreoretinal surgery such as the detection of the presence of otherwise invisible membranes (epiretinal membrane, subretinal membrane), the location of small tears and the identification of the retinal plane under suboptimal conditions for visualization. The use of an intra-ocular SD-OCT can expand upon visual cues during surgery, helping in the decision-making process and allowing additional deliberate surgical manoeuvres aimed at improving surgical outcomes. © 2016 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  6. Use of hydroxypropylmethylcellulose 2% for removing adherent silicone oil from silicone intraocular lenses

    OpenAIRE

    Wong , S Chien; Ramkissoon , Yashin D; Lopez , Mauricio; Page , Kristopher; Parkin , Ivan P; Sullivan , Paul M

    2009-01-01

    Abstract Background / aims: To investigate the effect of hydroxypropylmethylcellulose (HPMC) on the physical interaction (contact angle) between silicone oil and a silicone intraocular lens (IOL). Methods: In vitro experiments were performed, to determine the effect of HPMC (0.5%, 1% or 2%), with or without an additional simple mechanical manoeuvre, on the contact angle of silicone oil at the surface of both silicone and acrylic (control) IOLs. A balanced salt solu...

  7. Orbital cellulitis and intraocular abscess caused by migrating grass in a cat.

    Science.gov (United States)

    Tovar, Mari Carmen; Huguet, Eduardo; Gomezi, Miguel Angel

    2005-01-01

    We report an unusual case of orbital cellulitis in a cat. Drainage via the pterygopalatine fossa and medical treatment were performed. Failure of resolution and loss of ocular structure and visual function with a poor prognosis led to enucleation. During surgery, plant material and purulent exudate were present in the orbit. Histopathology showed an intraocular foreign body of grass that had migrated through the sclera causing a suprachoroidal abscess with choroidal and retinal detachment.

  8. Implantation of phakic intraocular lens in 3 patients with oculocutaneous albinism.

    Science.gov (United States)

    van Rijn, Gwyneth A; Snoek, Colette; Joosse, Maurits; Saxena, Ruchi; Luyten, Gregorius P M

    2013-10-01

    We present 3 cases with oculocutaneous albinism in which a high refractive error was optically corrected by implantation of an Artisan iris-fixated phakic intraocular lens, with a follow-up of 8 to 14 years. No author has a financial or proprietary interest in any material or method mentioned. Copyright © 2013 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  9. Outcomes of 23- and 25-gauge transconjunctival sutureless vitrectomies for dislocated intraocular lenses.

    Science.gov (United States)

    Bajgai, Priya; Tigari, Basavraj; Singh, Ramandeep

    2017-10-04

    To compare the outcome of 23-gauge as compared with 25-gauge transconjunctival sutureless vitrectomy (TSV) in the management of dislocated intraocular lenses (IOLs). Retrospective, non-consecutive, comparative, interventional case series. Patients with dislocated intraocular lens who underwent sutureless PPV using either 23-gauge or 25-gauge instruments. The patients who presented with a dislocated IOL, underwent TSV with repositioning of the intraocular lens, either in the sulcus or scleral-fixated sutured/glued. Of the total 61 eyes, 33 (54.09%) underwent 23-gauge TSV and 28 (45.90%) underwent 25-gauge TSV. The mean logMAR BCVA at baseline and 6 months after surgery was 0.8 and 0.46 in the 23-gauge group, and 0.82 and 0.47 in the 25-gauge group. There was no significant difference in logMAR BCVA values between the two groups at any time point of time during the follow-up. The mean postoperative IOP on postoperative day 1 was 14.76 ± 5.4 in 23-gauge group and 17.57 ± 7.9 in the 25-gauge group (p = 0.10). Retinal break was noticed intraoperatively in two cases in 23-gauge group and in three cases in 25-gauge group (p = 0.509). Postoperative complications included IOL decentration in one case of 23-gauge vitrectomy and two cases in 25-gauge group (p = 0.5), cystoid macular edema in four patients in 23-gauge group and six cases of 25-gauge group (p = 0.3) and retinal detachment in one case in each group (p = 0.9). 25-gauge appears to be as safe and as effective as 23-gauge TSV in the management of dislocated intraocular lenses.

  10. Surgical management of spontaneous in-the-bag intraocular lens and capsular tension ring complex dislocation

    Directory of Open Access Journals (Sweden)

    Uzeyir Gunenc

    2014-01-01

    Full Text Available We describe a technique to manage late spontaneous intraocular lens (IOL and capsular tension ring (CTR dislocation within the intact capsular bag. The subluxated IOL and CTR complex can be positioned in a closed chamber and fixed to the pars plana at both 3 and 9 o′clock quadrants with the presented ab externo direct scleral suturation technique which provides an easy, safe and effective surgical option for such cases.

  11. Intraocular Pressure After 2 Hours of Small-Diameter Scleral Lens Wear.

    Science.gov (United States)

    Nau, Cherie B; Schornack, Muriel M; McLaren, Jay W; Sit, Arthur J

    2016-11-01

    Compression of episcleral veins or deformation of tissue in the Schlemm's canal beneath the landing zone of scleral lenses could elevate intraocular pressure (IOP). We examined the effect of 2 hr of small-diameter scleral lens wear on IOP. Twenty-nine participants, 29 ± 6 years old (mean ± SD) who experienced no history of eye disease or scleral lens wear, were included in the study. Each participant was fitted with a 15-mm Jupiter scleral lens on one eye (study eye). Intraocular pressure was measured in both eyes by pneumatonometry centrally on the cornea and peripherally on the sclera. The lens was then placed on one eye and was worn for 2 hr. Intraocular pressure was remeasured immediately after lens placement, at 1 and 2 hr of lens wear, and immediately after lens removal. Intraocular pressure after removal of the scleral lens was compared with IOP before placing the lens and to IOP in the control eye using paired t tests. Immediately after removing the scleral lens, mean central IOP in the study eye (13.9 ± 3.1 mm Hg) was not different from mean central IOP in the control eye (13.5 ± 2.2 mm Hg, P = 0.4) or in the same eye before lens wear (13.6 ± 1.9 mm Hg, P = 0.6). There were also no differences in IOP measured peripherally at 2 hr of lens wear (P = 0.8). Neophyte scleral lens wear of a 15-mm scleral lens for 2 hr does not increase IOP in healthy eyes.

  12. Follow up of intraocular lens subluxation with a combined topographer/aberrometer

    OpenAIRE

    Georgios A. Kontadakis; George D. Kymionis; Vardhaman P. Kankariya; Ioannis G. Pallikaris

    2012-01-01

    Purpose: To report a 36-year-old patient with intraocular lens (IOL) subluxation that was followed for IOL stability with evaluation of images captured with the iTrace combined aberrometer/topographer. Methods: The patient had undergone phacoemulsification with IOL implantation for congenital cataract 15 years before. He presented with bilateral IOL subluxation, more severe in his right eye. Right eye was operated for IOL exchange and left eye was followed with the iTrace images. The image...

  13. Effects of tramadol and acepromazine on intraocular pressure and pupil diameter in young healthy cats

    OpenAIRE

    Schroder, Deise Cristine; Monteiro, Bianca Garay; Pytlak, Deborah Braga; Souza, Mayara Carvalho de; Mendonça, Adriane Jorge; Ribeiro, Alexandre Pinto

    2018-01-01

    ABSTRACT: This study aimed to investigate the effects of the systemic administration of acepromazine, tramadol and the association of both on intraocular pressure (IOP) and pupil diameter (PD) in young healthy cats. Cats were randomly allocated into three groups (n=10/each) and intramuscular acepromazine (AG), tramadol (TG) or acepromazine combined with tramadol (ATG) were injected. PD (electronic caliper) and IOP (applanation tonometry) were assessed before (baseline) and following 15, 30, 6...

  14. Use of intraocular lenses in children with traumatic cataract in south India

    OpenAIRE

    Eckstein, M.; Vijayalakshmi, P; Killedar, M.; Gilbert, C.; Foster, A.

    1998-01-01

    AIMS—To assess the long term results of intraocular lens (IOL) implantation for traumatic cataract in young children in a developing country.
METHODS—Prospective hospital based study of 52 children (age 2-10 years) undergoing unilateral cataract extraction and IOL insertion for traumatic cataract performed by a single surgeon in south India. Children were reviewed regularly and followed up initially for 3 years.
RESULTS—There were no serious operative complications. Clinically significant pos...

  15. Correlation of the intraocular pressure with increased intracranial pressure in rabbits

    Directory of Open Access Journals (Sweden)

    Eskandari H

    2000-08-01

    Full Text Available Although measurement of intracranial pressure by noninvasive methods has been suggested, but mainly invasive methods are used for this purpose-Increase in episcleral venous pressure can be expected to result in a linear increase in intraocular pressure. Congested oculat veins with capillary leakage and hemorrhage are seen when the ICP is increased, thus theoretically measurement of intraocular pressure can be a procedure for estimation of the ICP. This study was performed to find whether there is andy relationship between intraocular pressure and ICP, so we used 12 albino rabbits in two divided groups. Our study was not designed to elucidate the mechanism of change but merely to record any changes observed. All measures except an increase in ICP were applied on the test group as well as on the control group. After general anesthesia with the combination of ketamin, rampune, and pentobarbital a burr hole was made in the lambda region of the skull and a cannula was placed in the subdural space. The ICP in the test group increased up to 15 mmHg and was constant throughout the experiment. Intraocular pressure was measured by Schiotz tonometers afte general anesthesia, after cannulation of the skull, and immediately after increasing the ICP which was repated in 15 minutes interval for 4 hours. There was no statistical difference between the two groups (P:0.997 . results show that neither cannulation nor general anesthesia for 4 hours produce alteration in IOP in the control group nor increasing of the ICP to level of 15 mmHg produces any alteration in IOP on the test group.

  16. Caracterización del glaucoma juvenil

    Directory of Open Access Journals (Sweden)

    Silvia Roche Caso

    2011-03-01

    Full Text Available INTRODUCCIÓN. El glaucoma no es frecuente en los niños, pero cuando ocurre sus síntomas son poco perceptibles y produce graves consecuencias para la salud visual. El objetivo de este estudio fue caracterizar, desde las aristas clínica y epidemiológica, a los pacientes con glaucoma juvenil atendidos en los servicios de oftalmología de los Hospitales Pediátricos del Cerro y «Pedro Borrás», en Ciudad de La Habana, en el período comprendido entre enero de 2008 y diciembre de 2009. MÉTODOS. Se realizó un estudio epidemiológico longitudinal y prospectivo, cuyo universo estuvo constituido por 176 pacientes entre 5 y 18 años de edad, con presunto glaucoma. La muestra, después de aplicados los criterios de inclusión y exclusión, quedó conformada por 38 casos. Se analizaron las variables: edad al momento del diagnóstico, sexo, color de la piel, antecedentes familiares según grado de parentesco, agudeza visual máxima corregida, tipo de defecto refractivo, características del ángulo camerular, espesor corneal central, valor de la presión intraocular, alteraciones fundoscópicas y campimétricas. RESULTADOS. En la mayoría de los pacientes el diagnóstico de glaucoma juvenil constituyó un hallazgo. La mediana de edad al momento del diagnóstico fue de 12,5 años, con ligero predominio de varones y de la piel no blanca. Fue más frecuente el antecedente de glaucoma en familiares de segundo grado de consanguinidad. La mayoría de los casos tenía visión óptima, algún grado de miopía y ángulo abierto sin alteraciones evidentes del ángulo camerular, entre las cuales la más frecuente fue la presencia de procesos iridianos prominentes. CONCLUSIONES. Predominaron la disminución moderada del espesor corneal y valores medios de presión intraocular de 26,91 mm Hg. La alteración fundoscópica encontrada con mayor frecuencia fue la excavación papilar moderada (entre 0,4 y 0,5 y como lesión campimétrica, el aumento de la mancha

  17. Comparison of Tono-Pen AVIA intraocular pressure measurements performed at limbus with central corneal Tono-Pen AVIA intraocular pressure.

    Science.gov (United States)

    Sharma, Reetika; Majumdar, Saptorishi; Sobti, Amit; Arora, Tarun; Agarwal, Tushar; Dada, Tanuj

    2013-07-01

    To compare Tono-Pen AVIA (TPA) intraocular pressure (IOP) measurements performed at the limbus with central corneal Tono-Pen AVIA (TPA) intraocular pressure. Fifty-one patients attending our outpatient department with a best corrected visual acuity of ≥ 20/40, no corneal disease, and no astigmatism greater than 1.5 diopters underwent routine ophthalmological examination. Patients with ametropia greater than or equal to ± 5 diopters, a history of recent contact lens wear, and central corneal thickness of 550 µm were excluded from the study. IOP was recorded first in the corneal center, followed by tonometry measurements obtained from the temporal, nasal, superior, and inferior limbus using TPA. IOP measurements were compared using the paired t test. Correlation was derived by Pearson correlation coefficient, and regression equations were derived. The mean age of patients in our study was 43.86 ± 15.39 years. The mean TPA IOP from the central cornea was 16.59 ± 3.75 mm Hg. There was a statistically significant difference between Tono-Pen IOP from the central cornea and that recorded from all 4 limbal positions (P < 0.001). There was a positive correlation between the central and the limbal IOP obtained with Tono-Pen. Correlation was maximum for the temporal limbus. Limbal TPA IOP is significantly higher than central TPA IOP. There remains a good correlation between central and limbal IOP. This was found to be greatest for the temporal limbus.

  18. Long-term refractive change after intraocular lens implantation in childhood.

    Science.gov (United States)

    Walker, Randy A; Romanchuk, Kenneth G

    2006-08-01

    To determine refractive change occurring with age in children who had cataract removal with intraocular lens implantation and in whom the immediate postoperative refraction was targeted either to match the refractive error of the opposite eye in unilateral cases, or for only a small refractive error when surgery was bilateral. Retrospective review of the refractive error over time in 36 eyes of 25 children who underwent cataract removal (11 bilateral) with insertion of an intraocular lens from 1987 to 1998 and who had at least 4 years follow-up, but no glaucoma. Mean age at surgery was 5.5 years (median 5.7 y, range 1.3-12 y), with a mean follow-up of 8 years (median 6 y, range 4-16 y). The average refraction followed a logarithmic decline with age. Although eyes with unilateral surgery had a slightly faster rate of change and lower final refraction than did eyes with bilateral surgery, this difference was not statistically significant. Variation from this trend was also observed in 3 patients. When the hyperopic refractive error created immediately after surgery was small, children usually became significantly myopic when older, often creating anisometropic myopia in unilateral cases. When implanting intraocular lenses bilaterally one should aim for a significant but balanced hyperopic correction immediately postoperatively in young patients, anticipating that there will be emmetropization with aging. Parents should be warned that variations can occur.

  19. Two cases of uveitis masquerade syndrome caused by bilateral intraocular large B-cell lymphoma

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    Jovanović Svetlana

    2013-01-01

    Full Text Available Introduction. Sometimes it is not easy to clinically recognize subtle differences between intraocular lymphoma and noninfectious uveitis. The most common lymphoma subtype involving the eye is B-cell lymphoma. Case report. We presented two patients aged 59 and 58 years with infiltration of the subretinal space with a large B-cell non-Hodgkin intraocular lymphoma. The patients originally had clinically masked syndrome in the form of intermediate uveitis. As it was a corticosteroid-resistant uveitis, we focused on the possible diagnosis of neoplastic causes of this syndrome. During hospitalization, the neurological symptoms emerged and multiple subretinal changes accompanied by yellowish white patches of retinal pigment epithelium with signs of vitritis, which made us suspect the intraocular lymphoma. Endocranial magnetic resonance imaging established tumorous infiltration in the region of the left hemisphere of the cerebellum. The histopathological finding confirmed the diagnosis of large B-cell non-Hodgkin lymphoma of risk moderate degree, immunoblast - centroblast cytological type. The other patient had clinical chronic uveitis accompanied by yellowish shaped white echographic changes of the retina and localized changes in the level of the subretina. The diagnosis of lymphoma was made by brain biopsy. Conclusion. Uveitis masquerade syndrome should be considered in all patients over 40 years with idiopathic steroid-resistant uveitis. Treatment begun on time can affect the course and improve the prognosis of uveitis masquerade syndrome (UMS and systemic disease.

  20. Intravenous paracetamol and intraocular pressure reduction: mannitol may also be involved

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    Allegaert K

    2016-09-01

    Full Text Available Karel Allegaert1,2 1Intensive Care, Department of Surgery, Erasmus MC Sophia Children’s Hospital, Rotterdam, the Netherlands; 2Department of Development and Regeneration, KU Leuven, BelgiumI read, with great interest, the paper on the intraocular pressure-lowering properties of intravenous paracetamol (acetaminophen recently published in this journal by van den Heever and Meyer.1 The authors documented a decrease from baseline in mean intraocular pressure of 15.7% in a 6-hour time interval following intravenous paracetamol (1 g Perfalgan®, Bristol-Myers Squibb, New York, NY, USA administration. This mean decrease was moderate but relevant when compared to, for example, topical timolol (–25.3%, single drop 0.5% timolol maleate or oral acetazolamide (–23.1%, 250 mg. Although the authors provided potential relevant mechanistic arguments in support of a link between paracetamol administration and intraocular pressure through the endocannabinoid system, we would like to draw attention to the fact that – when intravenous paracetamol is administered – a relevant amount of mannitol is coadministered.View the original paper by van den Heever and Meyer

  1. Raised intraocular pressure and recurrence of retinal detachment as complications of external retinal detachment surgery

    International Nuclear Information System (INIS)

    Jawwad, M.; Khan, B.; Shah, M.A.; Qayyum, I.; Aftab, M.; Qayyum, I.

    2015-01-01

    Patients with Rhegmatogenous retinal detachment may develop raised intraocular pressure and recurrence of retinal detachment when they undergo external retinal detachment surgery. The present study was conducted to determine the postoperative rise in intraocular pressure (IOP) and recurrence of retinal detachment. Methods: The present descriptive study was conducted at Eye department of Lady Reading Hospital, Peshawar on 25 patients of both genders from August 2012 to July 2014. Results: Of the 25 patients, 18 (72%) developed raised IOP in the immediate postoperative period; this figure decreased to 12 (48%) at one week. Following medical or surgical intervention in these 12 cases, there was only 1 (4%) case with mildly raised IOP at two weeks postoperative. Five (20%) cases developed recurrent retinal detachment which later resolved with treatment. There were no significant differences by age or gender. Conclusion: External Retinal Detachment Surgery raised intraocular pressure postoperatively and caused recurrence of retinal detachment. These complications were treated medically and surgically with resolution within two weeks. (author)

  2. [Congenital lens subluxation: visual acuity outcomes and intraocular lens postoperative position].

    Science.gov (United States)

    Arraes, Caroline; Endriss, Daniela; Lobato, Francisco; Arraes, João; Ventura, Marcelo

    2010-01-01

    To evaluate the visual acuity outcomes and to investigate the intraocular lens (IOL) and endocapsular ring positions with ultrasound biomicroscopy in 17 eyes of 10 patients with congenital lens subluxation who underwent the same surgical technique, by the same surgeon. The study was performed in the ''Hospital de Olhos de Pernambuco'' and ''Fundação Altino Ventura''. The surgical technique consisted of phacoaspiration with implant of endocapsular ring and intraocular lens with one loop haptic amputated. The age varied from 7 to 22 years. Data on visual acuity (VA) before and after surgery, surgery follow-up period, and complications were analyzed. All patients underwent ultrasound biomicroscopy. The mean follow-up period was 2.8 years. There was a VA improvement in 17 (100%) eyes: in 12 eyes (70.6%) the visual acuity was better than 20/40; 4 (23.5%) ranged from 20/40 to 20/100, and 1 (5.9%) had visual acuity worse than 20/100, however better than the preoperative visual acuity. The posterior capsular opacification occurred in 10 eyes (58.9%). Ultrasound biomicroscopy showed that all IOL were partially decentralized, however without surpassing the pupil border limit. Endocapsular ring position was correct and there was a good capsular support in all cases. The evaluated surgical treatment provided good intraocular lens and endocapsular ring position, with VA improvement Thus, this technique is a viable, effective and safe option for the visual rehabilitation of patients with congenital lens subluxation.

  3. Retropupillary Fixation of Iris-Claw Intraocular Lens for Aphakic Eyes in Children

    Science.gov (United States)

    Brandner, Martina; Thaler-Saliba, Sarah; Plainer, Sophie; Vidic, Bertram; El-Shabrawi, Yosuf; Ardjomand, Navid

    2015-01-01

    Purpose To report outcome, complications and safety of retropupillary fixated iris-claw intraocular lenses in a pediatric population. Design Retrospective study. Patients and Methods Ten consecutive pediatric patients (15 eyes) underwent placement of retropupillary fixated iris-claw intraocular lenses between October 2007 and July 2013 at the Department of Ophthalmology, Medical University Graz and General Hospital Klagenfurt, Austria. Postoperative visual acuity and complications were analyzed. Results Median final best-corrected visual acuity improved by 0.12 logMAR from preoperative baseline. Mean postoperative spherical equivalent was -0.05 ± 1.76 D. No serious complications were observed intra- or postoperatively during the entire follow-up period of up to 40 months. One patient experienced a haptic disenclavation with IOL subluxation immediately after a car accident. Conclusion Our study demonstrates that iris-claw intraocular lens implantation behind the iris is safe in children with lack of capsular support and yields excellent visual outcome with low complication rate. PMID:26110864

  4. Retropupillary Fixation of Iris-Claw Intraocular Lens for Aphakic Eyes in Children.

    Directory of Open Access Journals (Sweden)

    Martina Brandner

    Full Text Available To report outcome, complications and safety of retropupillary fixated iris-claw intraocular lenses in a pediatric population.Retrospective study.Ten consecutive pediatric patients (15 eyes underwent placement of retropupillary fixated iris-claw intraocular lenses between October 2007 and July 2013 at the Department of Ophthalmology, Medical University Graz and General Hospital Klagenfurt, Austria. Postoperative visual acuity and complications were analyzed.Median final best-corrected visual acuity improved by 0.12 logMAR from preoperative baseline. Mean postoperative spherical equivalent was -0.05 ± 1.76 D. No serious complications were observed intra- or postoperatively during the entire follow-up period of up to 40 months. One patient experienced a haptic disenclavation with IOL subluxation immediately after a car accident.Our study demonstrates that iris-claw intraocular lens implantation behind the iris is safe in children with lack of capsular support and yields excellent visual outcome with low complication rate.

  5. Clinical study of AcrySof IQ Toric intraocular lens implantation to corneal correct astigmatism

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    Qian Wang

    2014-09-01

    Full Text Available AIM: To observe the clinical outcome of implanting AcrySof IQ Toric intraocular lens to correct corneal astigmatism in cataract surgery, and to evaluate the result and rotational stability of AcrySof IQ Toric after cataract surgery. METHODS: A retrospective study of 26 eyes in 21 cataract patients with corneal astigmatism. All patients implanted AcrySof IQ Toric intraocular lens. The preoperative and postoperative uncorrected visual acuity(UCVA, best corrected visual acuity(BCVA, preoperative corneal astigmatism, anticipated residual astigmatism, total astigmatism, postoperative residual astigmatism and Toric lens axis were detected and measured.RESULTS: All patients' visual acuity and best corrected visual acuity improved significantly. The mean refractive cylinder decreased significantly after surgery from(2.05±0.57D to(0.55±0.33D(t=13.574, Pt=1.149, P>0.05. Three months after surgery, there was no significant difference between preoperative(2.01±0.58D and postoperative(-1.89±0.53D corneal astigmatism(t=1.908, P>0.05. The rotation of intraocular lens were CONCLUSION: The AcrySof IQ Toric lens make cataract patients enjoy the better UCVA including good rotational stability in the correct of corneal astigmatism. The AcrySof IQ Toric implantation is an effective option for the correct of preexisting corneal astigmatism in cataract surgery.

  6. [Evaluation of colour vision according to type of implanted artificial foldable intraocular lens].

    Science.gov (United States)

    Stopyra, Wiktor

    2012-01-01

    The aim of research was comparing the colour vision of patients with blue light filtering artificial lens to the patients with implant without blue light filter. 99 patients (120 eyes) divided on three groups were examined. 40 patients (40 eyes) after cataract surgery with implantation of blue light filtering lens were the first group. 39 patients (40 eyes) who had implanted lens without filter were the second group. 20 patients (40 eyes) with own transparent lens were the third group. Farnsworth-Munsell 100 Hue test was used in research. Each patient made test on thirtieth day after cataract surgery. Following average total error score (TES) values in groups were observed: the first group--60.66, the second group--83.71, the third group--61.55. Average axis of disorder in blue-yellow range was following: patients after cataract surgery with implantation of blue light filtering lens--5.48, patients with implant without blue light filter--7.28, control group--5.74. 1. Kind of artificial intraocular lens has meaning in colour vision at pseudophakic patients. 2. Blue light filter of artificial intraocular foldable lens advantageously effects perception of colours. 3. Lack of blue light filter in artificial intraocular lens gets worse colour vision especially in blue-yellow range.

  7. Estudio del seno coronario y sus tributarias en individuos colombianos

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    Luis E. Ballesteros, MD., MSc.

    2010-01-01

    Full Text Available La expresión morfológica del seno coronario se caracteriza por su gran variabilidad, especialmente en lo que se relaciona con longitud, calibres, territorios drenados y frecuencia de sus tributarias. Se evaluaron las variaciones del seno coronario en 68 senos coronarios (56 hombres; 12 mujeres de corazones extraídos como material de necropsia, a individuos colombianos. Los senos fueron inyectados con resina sintética y se registraron sus características anatómicas. La longitud promedio de los senos fue de 25,96 mm (± 6,34 y su diámetro distal de 8,94 mm (± 1,66. Las formas fueron cilíndrica, en embudo y aplanada en 67,6%, 23,5% y 8,9% respectivamente. La vena cardiaca magna se originó en el ápex cardiaco en 57,4% de los casos y en el tercio inferior del surco interventricular anterior en 39,7%. A nivel del surco atrioventricular tuvo un calibre de 5,47 mm (± 0,72. En 77,9% la vena cardiaca magna se ubicó a la izquierda de la arteria interventricular anterior. El trígono arterio-venoso del corazón estuvo presente en 58,8%. La vena cardiaca media tuvo como origen el tercio inferior de la superficie ventricular anterior (53% y el ápex cardiaco (47%. Ésta desembocó directamente en el atrio derecho en 17% de los casos. Su calibre en el segmento cercano al seno fue de 4 mm (± 0,77. Se presentó anastomosis de las venas cardiacas magna y media en 58,8%; en el ápex cardiaco (33,8% y en el segmento inferior del surco interventricular anterior. Se destaca la presencia de una vena cardiaca magna corta y de una vena cardiaca media de amplia trayectoria en un número significativo de casos. De igual forma, la desembocadura de la vena cardiaca media en el atrio derecho estuvo presente en casi una quinta parte de los corazones estudiados.

  8. Optimización del proceso de producción de la Fábrica de Calzado Giancarlo

    OpenAIRE

    Cazorla Orellana, Pablo Alberto; Peralta Molina, Paúl Fernando

    2007-01-01

    La vida moderna en constante desarrollo y la actual globalización de los negocios, determinan la necesidad de expandir los mercados de la Fábrica de Calzado Giancarlo a través del aumento de nuestra capacidad de reacción, haciéndonos más competitivos, fortaleciendo las estructuras empresariales e identificado claramente los segmentos a los cuales nos dirigimos. Las herramientas metodológicas con las que cuenta la Ingeniería Industrial permiten obtener ventajas considerables en la manufact...

  9. Implementación del sistema de venta de recarga virtual para distribuidores de una empresa de telecomunicaciones

    OpenAIRE

    Ibarra Apaza, Wilson Daniel; Ibarra Apaza, Wilson Daniel

    2012-01-01

    En la actualidad se ha observa que el Sector de las Telecomunicaciones ha ido creciendo notablemente, esto debido en parte al crecimiento económico del país en los últimos años, lo cual ha traído consigo oportunidades de negocio para las empresas de telecomunicaciones, quienes constantemente ofrecen productos y servicios de calidad enfocados a la satisfacción de los clientes, con la finalidad de retener a los clientes y atraer nuevos clientes de segmentos que aún no han sido explorados y que ...

  10. The effect of increased intra-abdominal pressure on orbital subarachnoid space width and intraocular pressure

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    Su-meng Liu

    2018-01-01

    Full Text Available In accordance with the trans-lamina cribrosa pressure difference theory, decreasing the trans-lamina cribrosa pressure difference can relieve glaucomatous optic neuropathy. Increased intracranial pressure can also reduce optic nerve damage in glaucoma patients, and a safe, effective and noninvasive way to achieve this is by increasing the intra-abdominal pressure. The purpose of this study was to observe the changes in orbital subarachnoid space width and intraocular pressure at elevated intra-abdominal pressure. An inflatable abdominal belt was tied to each of 15 healthy volunteers, aged 22–30 years (12 females and 3 males, at the navel level, without applying pressure to the abdomen, before they laid in the magnetic resonance imaging machine. The baseline orbital subarachnoid space width around the optic nerve was measured by magnetic resonance imaging at 1, 3, 9, and 15 mm behind the globe. The abdominal belt was inflated to increase the pressure to 40 mmHg (1 mmHg = 0.133 kPa, then the orbital subarachnoid space width was measured every 10 minutes for 2 hours. After removal of the pressure, the measurement was repeated 10 and 20 minutes later. In a separate trial, the intraocular pressure was measured for all the subjects at the same time points, before, during and after elevated intra-abdominal pressure. Results showed that the baseline mean orbital subarachnoid space width was 0.88 ± 0.1 mm (range: 0.77–1.05 mm, 0.77 ± 0.11 mm (range: 0.60–0.94 mm, 0.70 ± 0.08 mm (range: 0.62–0.80 mm, and 0.68 ± 0.08 mm (range: 0.57–0.77 mm at 1, 3, 9, and 15 mm behind the globe, respectively. During the elevated intra-abdominal pressure, the orbital subarachnoid space width increased from the baseline and dilation of the optic nerve sheath was significant at 1, 3 and 9 mm behind the globe. After decompression of the abdominal pressure, the orbital subarachnoid space width normalized and returned to the baseline value. There was no

  11. The effect of increased intra-abdominal pressure on orbital subarachnoid space width and intraocular pressure.

    Science.gov (United States)

    Liu, Su-Meng; Wang, Ning-Li; Zuo, Zhen-Tao; Chen, Wei-Wei; Yang, Di-Ya; Li, Zhen; Cao, Yi-Wen

    2018-02-01

    In accordance with the trans-lamina cribrosa pressure difference theory, decreasing the trans-lamina cribrosa pressure difference can relieve glaucomatous optic neuropathy. Increased intracranial pressure can also reduce optic nerve damage in glaucoma patients, and a safe, effective and noninvasive way to achieve this is by increasing the intra-abdominal pressure. The purpose of this study was to observe the changes in orbital subarachnoid space width and intraocular pressure at elevated intra-abdominal pressure. An inflatable abdominal belt was tied to each of 15 healthy volunteers, aged 22-30 years (12 females and 3 males), at the navel level, without applying pressure to the abdomen, before they laid in the magnetic resonance imaging machine. The baseline orbital subarachnoid space width around the optic nerve was measured by magnetic resonance imaging at 1, 3, 9, and 15 mm behind the globe. The abdominal belt was inflated to increase the pressure to 40 mmHg (1 mmHg = 0.133 kPa), then the orbital subarachnoid space width was measured every 10 minutes for 2 hours. After removal of the pressure, the measurement was repeated 10 and 20 minutes later. In a separate trial, the intraocular pressure was measured for all the subjects at the same time points, before, during and after elevated intra-abdominal pressure. Results showed that the baseline mean orbital subarachnoid space width was 0.88 ± 0.1 mm (range: 0.77-1.05 mm), 0.77 ± 0.11 mm (range: 0.60-0.94 mm), 0.70 ± 0.08 mm (range: 0.62-0.80 mm), and 0.68 ± 0.08 mm (range: 0.57-0.77 mm) at 1, 3, 9, and 15 mm behind the globe, respectively. During the elevated intra-abdominal pressure, the orbital subarachnoid space width increased from the baseline and dilation of the optic nerve sheath was significant at 1, 3 and 9 mm behind the globe. After decompression of the abdominal pressure, the orbital subarachnoid space width normalized and returned to the baseline value. There was no significant difference in the

  12. A TERRITORIALIZAÇÃO DO SEGMENTO CALÇADISTA EM JAÚ: Arranjo produtivo local, atores e governança

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    Lucas Labigalini Fuini

    2014-04-01

    Full Text Available O presente artigo tem como objetivo identificar os principais elementos constituintes do Arranjo Produtivo Local (APL especializado na fabricação de calçados femininos de Jaú e região, em um conjunto de municípios localizados na parte central do Estado de São Paulo. Trabalha-se com a hipótese de que a constituição dessa aglomeração produtiva, uma das quatro maiores produtoras do segmento no Estado, está atrelada a uma estrutura de governança própria envolvendo atores e instituições em inter-relação e hierarquizados em termos de poderes econômicos e políticos, mesclando cooperação e conflito. O APL de couro e calçados de Jaú é formado por Jaú, segundo maior produtor individual de calçados do Estado de São Paulo, e mais nove municípios de pequeno porte em seu entorno e que possuem elos da cadeia calçadista em seu território (produção final e/ou fornecimento de insumos da cadeia produtiva. A principal concentração industrial, de infraestrutura e de serviços especializados dessa região se concentra em Jaú, tradição que remete às primeiras oficinas de sapateiros dos anos de 1920 e 1930 do século passado. A constituição de um APL se inicia em fins dos anos 1990 e se aprofunda no início dos 2000, com a inclusão da região e seus municípios produtores de calçados no programa estadual de fortalecimento da competitividade em APLs. A territorialização da indústria calçadista em Jaú remete ao quadro composto pelos atores públicos e privados que participam da governança da política estadual de APLs em nível espacial regional e local e, nesse sentido, se deu a construção de uma rede de poder socioterritorial pautada na constante relação de cooperação e conflito envolvendo atores, normas, instituições e convenções articuladas envoltas em planos e programas de ação.

  13. Potencial econômico dos principais segmentos da cadeia produtiva do girassol nas regiões Vale do Rio Pardo e Vale do Taquari, RS

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    Jorge L. Amaral de Moraes

    2012-01-01

    Full Text Available O território formado pelas regi��es Vale do Rio Pardo e Vale do Taquari (RSaproveitou a oportunidade do mercado externo e as potencialidades de seusrecursos, como o grande contingente de agricultores familiares, para expandir aprodução de tabaco. As instituições locais buscam identificar atividades rentáveis eimplementar uma estrutura de diversificação da economia agrícola da região. Comoresultado dessa busca por alternativas produtivas agroalimentares e agroindustriais,a cadeia produtiva e os produtos derivados do girassol (grãos, farelo, óleo ebiodiesel aparecem como uma alternativa de diversificação produtiva a seranalisada. Este texto apresenta o resultado de uma análise econômica do potencialda cadeia produtiva do girassol como alternativa dinamizadora do desenvolvimentodo território. Foi realizada uma análise de rentabilidade e uma projeção de expansãode segmentos da cadeia produtiva do girassol, como a produção e a comercializaçãodo grão, óleo, torta e do biodiesel de girassol e seus potenciais efeitos sobre ademanda nos mercados de matérias-primas agroindustriais. Considerando os atuaispreços de mercado, verificou-se a inviabilidade da utilização do óleo de girassol paraa produção de biodiesel.Abstract The territory formed by regions Vale do Rio Pardo and Vale do Taquari (RStook the opportunity of the foreign Market and the potential of their resources, as thelarge contingent of family farmers, to expand the production of tobacco. Localinstitutions have sought to identify profitable activities and implement a diversificationof the agricultural production, the productive chain and the products derived fromsunflower (beans, meal, oil and biodiesel appear as an alternative to diversifyproduction to be analyzed. This paper presents the results of an economic analysis ofthe potential productive of the chain of the sunflower as an alternative fosters thedevelopment of the territory. It was performed an

  14. Análisis Comparativo de las Prácticas de Negocio Basadas en Tecnología en Empresas delSector Comercio Minorista. Un enfoque binacional en la zona fronteriza de Tamaulipas-Texas

    OpenAIRE

    Victoria E. Erosa Martín

    2010-01-01

    Las micro y pequeñas empresas del sector de comercio al menudeo también están involucradas en prácticas de negocio habilitadas por tecnología. Siendo un importante segmento de mercado para los proveedores de productos de consumo que operan en el marco de la administración de la cadena de abasto, los formatos comerciales del tipo de las “tienditas de la esquina”, las “tiendas de abarrotes” y otras de los giros de farmacia, ropa, papelería, etc., han incursionado en la operación de procesos hab...

  15. Exploración de consumo de servicios de turismo rural de la provincia del tequendama en cundinamarca, colombia, a través de las agencias operadoras de turismo de bogotá

    OpenAIRE

    Combariza G., Juliana; Aranda C., Yesid

    2009-01-01

    Se realizó un estudio exploratorio del segmento de consumo intermedio de servicios de turismo rural en la Provincia del Tequendama, Cundinamarca, a partir de la información suministrada por las agencias operadoras de turismo que ofertan estos servicios en la ciudad de Bogotá y registradas ante el Ministerio de Industria, Comercio y Turismo en el año 2007. Se identificaron las tendencias en el consumo de los turistas de la ciudad de Bogotá que adquieren productos...

  16. Prótese intra-ocular de resina acrílica em cães e gatos Acrylic resin intraocular prosthesis in dogs and cats

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    S.C. Rahal

    2000-08-01

    Full Text Available Foram atendidos no Hospital Veterinário da Faculdade de Medicina Veterinária e Zootecnia da Unesp - Campus de Botucatu, 11 animais (oito cães e três gatos, com alterações oftálmicas unilaterais graves que levaram à perda total da função ocular (protrusão de globo com injúria nervosa e estrutural, perfurações de córnea com perda de conteúdo intra-ocular e endoftalmites, entre outras. Os animais, com idades entre dois meses e 10 anos, foram submetidos à evisceração e posterior inclusão de esfera de resina acrílica (metilmetacrilato na capa córneo-escleral ou escleral. As esferas foram previamente confeccionadas e esterilizadas por autoclavagem. No pós-operatório foram utilizados antiinflamatórios e antibioticoterapia tópica combinada ou não a sistêmica. O período de observação variou de 2 meses a 3 anos e os aspectos avaliados foram secreção ocular, blefarospasmo, sinais de desconforto e estética. Obtiveram-se resultados satisfatórios em oito casos. Concluiu-se que a resina acrílica pode ser uma alternativa para uso como inclusão em cavidade anoftálmica.Eleven animals (eight dogs and three cats, aged between two months and ten years were referred to the Veterinary Hospital of Faculty of Veterinary Medicine and Animal Science - Unesp, Botucatu, Brazil. These animals presented severe unilateral ophthalmic changes that lead to a total loss of ocular function, such as prolapsed eyes with nervous and structural injury, corneal damage with loss of intraocular contents or endophthalmitis among others. They were submitted to evisceration followed by the insertion of an acrylic resin prosthesis (methylmethacrylate in the corneoscleral or scleral shell. The spheres were previously made and sterilized by autoclave. The postoperative medical therapy included topical and systemic broad-spectrum antibiotics for seven days and anti-inflammatory drugs. The follow-up time varied from two months to three years. The evaluated

  17. Características del síndrome coronario agudo en pacientes ancianos españoles

    OpenAIRE

    Cabrerizo-García, José Luis; Zalba-Etayo, Begoña

    2013-01-01

    Objetivos Los pacientes ancianos que sufren un síndrome coronario agudo (SCA) de alto riesgo están escasamente representados en trabajos de investigación y guías de práctica clínica. El objetivo del trabajo es conocer las características del SCA de alto riesgo en pacientes de >75 años.Métodos Estudio prospectivo descriptivo de 161 pacientes de >75 años con SCA con y sin elevación del segmento ST de alto riesgo según criterios de la ACA/AHA. Se recogieron variables analíticas, electrocar...

  18. Nueva especie de Tityus (Scorpiones: Buthidae del Turimiquire, Venezuela

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    Leonardo De Sousa

    2006-06-01

    Full Text Available Se describe una nueva especie de la familia Buthidae, Tityus quirogae, del Macizo del Turimiquire en el tramo oriental de la Cordillera de La Costa en los Estados Monagas y Sucre, Venezuela. Es similar, morfológicamente, a T. nematochirus y T. meridanus. Se distingue de estas especies por la disposición de las tricobotrias dorsales del fémur y por presentar la siguiente combinación de características: (1 I Segmento caudal con dos carenas ventrales paralelas. Segmentos caudales II al IV con carenas ventrales dobles hacia el área proximal que convergen y se hacen únicas, para finalmente ser divergentes hacia la región distal, (2 marcado dimorfismo sexual, especialmente en la forma de los pedipalpos; las quelas en los machos son marcadamente delgadas y largas, (3 número de dientes pectíneos (macho: 18 derechos y 18 izquierdos y hembra: 18 derechos y 19 izquierdos, (4 número de hileras de dentículos del dedo móvil de la mano derecha (macho 16 y hembra 16. T. quirogae es la primera especie del género con pedipalpos delgados y alargados para la región nororiental de Venezuela.A new species of Tityus (Scorpiones: Buthidae from Turimiquire, Venezuela. We describe a new species of Buthid scorpion, Tityus quirogae, from the Turimiquire mountains, eastern side of the La Costa range, Monagas and Sucre States, Venezuela. It is morphologically similar to T. nematochirus and T. meridanus. It differs from these species in the distribution of the dorsal femoral trichobothria and in the following combination of characters: (1 I caudal segment with two parallel ventral keels. Caudal segments II to IV with ventral keels that are double in the extremes of the segments and single in the middle, (2 noticeable sexual dimorphism, especially in pedipalp shape; the male chelae are markedly thin and long, (3 number of pectineous teeth (male: 18 in each pecten; female: 18 in the right pecten and 19 in the left one, and (4 number of denticle rows in the

  19. PATRIMÔNIO CULTURAL, EDUCAÇÃO E TURISMO: PROPOSTA DE UM SISTEMA DE CAPACITAÇÃO CONTINUADA PARA AS CATEGORIAS ENVOLVIDAS NO SEGMENTO TURÍSTICO GOIANIENSE - Projeto de Gestão

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    Ferraz, Maria Odete de Oliveira

    2005-01-01

    Este projeto de Educação Patrimonial propõe a criação de um sistema de capacitação continuada para as categorias envolvidas no segmento turístico goianiense, enfocando o setor de transportes como primeira categoria, em específico os condutores de táxis. O trabalho foi fundamentado a partir da idéia de que o patrimônio cultural deve ser gerido de forma a possibilitar uma múltipla visão e interpretação de seus significados, nomeando como principal diferencial um curso que proporc...

  20. Empreendedorismo no segmento esportivo: uma análise da intenção empreendedora do estudante de educação física no Estado de São Paulo

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    Moura Junior, Luiz Geraldo de Souza

    2017-01-01

    Dissertação de Mestrado em Gestão O Brasil, ocupando a posição de sexta economia mundial (2011), se destaca a cada ano, como um país empreendedor. Em pesquisa recente do Global Entrepreneurship Monitor, o país é o décimo colocado entre cinquenta países pesquisados. O segmento esportivo no Brasil está em crescimento constante no que se refere a projetos e investimento pra receber grandes eventos esportivos. Por outro lado, buscamos com esse projeto verificar se o empreendedor...

  1. Percepeções e anseios dos atores envolvidos no segmento de turismo rural: um estudo de caso no município de Foz do Iguaçu/PR

    OpenAIRE

    Sodré, Samantha Trentin

    2015-01-01

    Trabalho de Conclusão de Curso apresentado ao Instituto Latino-Americano de Economia, Sociedade e Política da Universidade Federal da Integração Latino-Americana, como requisito parcial à obtenção do título de Bacharel em Desenvolvimento Rural e Segurança Alimentar. Orientadora: Prof. Dra. Ana Alice Aguiar Eleuterio O segmento do turismo rural é desenvolvido em áreas rurais produtivas, nas quais o turista tem a possibilidade de participa...

  2. Influence of gross saponins from tribulus terrestris L on SOD activity and MDA content for chronic high intraocular pressure in rabbit

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    Nuo Li

    2013-05-01

    Full Text Available AIM:To observe influence of gross saponins from tribulus terrestris L(GSTTon SOD activity and MDA content for chronic high intraocular pressure in rabbit, and discusses the retina oxidative damage inhibition on chronic high intraocular pressure model of rabbit. METHODS:Totally 24 healthy New Zealand rabbits were randomly divided into 4 groups: normal control group(A group; high intraocular pressure model blank group(B group; high intraocular pressure model with GSTT treated group(C group; high intraocular pressure model with Erigeron brevicapas hand mass(EBHMtreated group(D group. High intraocular pressure model was induced by 20g/L methylcellulose injection into the anterior chamber in B group, C group and D group. D group was injected 5 mg/kg GSTT and C group was injected 4.5mg/kg EBHM and measured intraocular pressure with Schiotz tonometer every day for 4 weeks. The retina tissue superoxide dismutase(SODand maleic dialdehyde(MDAcontent were detected 28 days later. RESULTS: After glaucoma model of rabbit eyes were established, the intraocular pressure during observation period was maintained in 32-39mmHg; High intraocular pressure model blank group and normal control group, EBHM treatment group, GSTT treatment group were compared, the differences of retina MDA, SOD content had statistical significance(P0.05; EBHM treatment group, GSTT treatment group and normal control group were compared, the content of MDA in the retina was still slightly higher(P<0.05, the content of SOD slightly lower(P<0.05 CONCLUSION: GSTT can effectively improve the retina SOD activity of chronic high intraocular pressure in rabbit and reduce the content of MDA, which has a protective effect of persistent high intraocular retinal oxidative stress.

  3. Descripción del estado de megalopa de Emerita analoga (Stimpson, 1857 (Decapoda, Anomura, Hippidae

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    Armando Mujica

    2015-03-01

    Full Text Available Se describe el estado de megalopas sobre la base de larvas de Emerita analoga, capturadas en la costa central de Chile (Coquimbo, como complemento al conocimiento de la morfología del desarrollo larval de esta especie, considerando que no ha sido descrita en estudios previos. La morfología general de la megalopa y la estructura de sus apéndices tienen gran similitud con los juveniles, lo que permite su identificación específica. Caracteres morfológicos, como el número de segmentos de los apéndices y su setación, proporcionan caracteres consistentes en su identificación y permiten diferenciarlas de las megalopas de otras especies del género, a pesar de su similitud con ellas.

  4. EL GÉNERO DEL CONSUMO EN LA SOCIEDAD DE CONSUMO

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    ALBA CAROSIO

    2008-01-01

    Full Text Available Este artículo analiza el surgimiento de la sociedad de consumo occidental, mostrando sus características como mecanismo de disciplinamiento social y motor de la producción, de manera tal que actúa como viabilizador del sistema capitalista. El consumo como modelo civilizatorio ha fabricado, para lograr su implantación en la vida cotidiana, un nuevo tipo de mujeres: las consumidoras. Responsables de 80% de las decisiones de compra en los hogares, las consumidoras son el segmento más manipulado y apetecido por la gerencia de mercadeo de las corporaciones, privilegiadas destinatarias y personajes protagónicos de los discursos publicitarios. La mujer consumidora está en el cruce de la promesa de felicidad que la cultura del consumo propone a los capaces de adquirir, con la contracara de pobreza invisible que la sustenta.

  5. Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility.

    Science.gov (United States)

    Chintalapudi, Sumana R; Maria, Doaa; Di Wang, Xiang; Bailey, Jessica N Cooke; Hysi, Pirro G; Wiggs, Janey L; Williams, Robert W; Jablonski, Monica M

    2017-11-24

    Glaucoma is a multi-factorial blinding disease in which genetic factors play an important role. Elevated intraocular pressure is a highly heritable risk factor for primary open angle glaucoma and currently the only target for glaucoma therapy. Our study helps to better understand underlying genetic and molecular mechanisms that regulate intraocular pressure, and identifies a new candidate gene, Cacna2d1, that modulates intraocular pressure and a promising therapeutic, pregabalin, which binds to CACNA2D1 protein and lowers intraocular pressure significantly. Because our study utilizes a genetically diverse population of mice with known sequence variants, we are able to determine that the intraocular pressure-lowering effect of pregabalin is dependent on the Cacna2d1 haplotype. Using human genome-wide association study (GWAS) data, evidence for association of a CACNA2D1 single-nucleotide polymorphism and primary open angle glaucoma is found. Importantly, these results demonstrate that our systems genetics approach represents an efficient method to identify genetic variation that can guide the selection of therapeutic targets.

  6. Aderência bacteriana in vitro a lentes intra-oculares de polimetilmetacrilato e de silicone In vitro bacterial adherence to silicone and polymetylmethacrylate intraocular lenses

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    Claudete Inês Locatelli

    2004-04-01

    Full Text Available OBJETIVOS: Verificar a aderência bacteriana a lentes intra-oculares de silicone e de polimetilmetacrilato como possível fator de risco no desenvolvimento de endoftalmite pós-operatória, utilizando-se um modelo in vitro com três microrganismos potencialmente patogênicos. MÉTODOS: As análises foram realizadas com cepas de Staphylococcus aureus ATCC 29213, Staphylococcus epidermidis (amostra clínica e Pseudomonas aeruginosa ATCC 27853 incluindo a determinação de curvas de crescimento, testes para verificação de produção de cápsula, avaliação da hidrofobicidade, testes de aderência a diferentes materiais, microscopia óptica, microscopia eletrônica de varredura e microscopia de força atômica. RESULTADOS: A produção de cápsula e a aderência das três diferentes cepas não mostraram qualquer relação com a quantidade de microrganismos; em relação às lentes intra-oculares de polimetilmetacrilato e de silicone, não houve diferença estatisticamente significativa na aderência de S. aureus e S. epidermidis; P. aeruginosa foi o microrganismo mais aderente a ambos os materiais. A microscopia eletrônica de varredura confirmou estes achados em relação à aderência, ao peso que a microscopia de força atômica evidenciou a produção de biofilme pelas cepas de S. aureus, S. epidermidis e P. aeruginosa. CONCLUSÕES: Constatou-se, in vitro, que os materiais analisados não diferiram com relação à taxa de aderência bacteriana, porém, P. aeruginosa apresentou maior eficiência de adesão entre as bactérias testadas. Todas as cepas produziram biofilme. Silicone foi o material mais hidrofóbico, quando comparado ao polimetilmetacrilato.PURPOSE: To evaluate bacterial adherence to silicone and polymetylmethacrylate (PMMA intraocular lenses as a risk factor for postsurgery endophthalmitis by using an in vitro model with three potentially pathogenic microorganisms. METHODS: In vitro experiments were carried out with the

  7. Vitrectomía pars plana y reimplante de lente intraocular en surco Pars plana vitrectomy and intraocular lens repositioning in the sulcus

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    Alejandro Guerra García

    2010-01-01

    Full Text Available Se presentó un caso de lente intraocular luxado a vítreo en paciente con conteo bajo de células endoteliales e intolerancia a lentes de contacto. Se practicó vitrectomía pars plana con reimplante de lente en surco ciliar con el objetivo de demostrar la fiabilidad de la técnica para casos que presenten condiciones adecuadas y situaciones especiales. Se revisó la bibliografía para conocer las tendencias actuales con respecto al manejo de esta patología. El paciente alcanzó una agudeza visual de 20/30. El lente permaneció estable en el surco 3 meses después de practicada la vitrectomía. El manejo de esta entidad debe ser personalizado. La técnica utilizada debe ser siempre la primera opción de tratamiento y parece ser segura en casos cuidadosamente escogidos.A case of dislocated intraocular lens moved to the vitreous cavity in a patient with low endothelial cell count and contact lens intolerance was reported. A pars plana vitrectomy with lens repositioning was performed to demonstrate the safety of this technique for some special cases under adequate conditions. The literature was reviewed to learn about the current management of this pathology. Finally, patient's best visual acuity was 20/30. The stability of the lens was confirmed three month l after the vitrectomy. Management of this disorder should be customized. This technique should be considered as the first option of treatment and seems to be safe in selected cases.

  8. Effects of Cataract Surgery on Intraocular Pressure in Patients with and without Glaucoma

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    Tülin İsmi

    2013-06-01

    Full Text Available Pur po se: To evaluate the effects of phacoemulsification surgery with primary intraocular lens (IOL implantation on intraocular pressure (IOP in various types of glaucoma patients with visually significant cataract and to compare these results with cataract patients without glaucoma. Ma te ri al and Met hod: This retrospective study included consecutive cases of 21 primary open-angle glaucoma patients, 13 primary angle-closure glaucoma (PACG patients, 11 pseudoexfoliation glaucoma patients, and 21 control eyes without any type of glaucoma; all patients had co-existing cataract. Visual acuities, IOP, number of glaucoma medications used, anterior chamber depth (ACD, and gonioscopic evaluations were noted both pre- and postoperatively. Phacoemulsification and IOL implantations were performed via clear corneal incisions in the whole study group. Study group was followed-up for six months. Re sults: Postoperative visits at the 1st, 3rd, and 6th months were noted. After surgery, visual acuities improved significantly (p=0.001 in all groups. Intraocular pressures decreased in all groups postoperatively, but the change was statistically significant in the PACG group (p=0.013. Increase in ACD was significant in PACG group (p=0.001. Widening of iridocorneal angle and decrease in the number of antiglaucoma drugs were observed in all groups, but these were significant in the PACG group (p=0.001 and p<0.05, respectively. Dis cus si on: In glaucoma patients with co-existing cataract, phacoemulsification surgery allows both the visual rehabilitation and IOP control. This IOP lowering effect is seen most markedly in the PACG group. (Turk J Ophthalmol 2013; 43: 167-72

  9. Densiron® 68 as an intraocular tamponade for complex inferior retinal detachments

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    Hussain RN

    2011-05-01

    Full Text Available Rumana N Hussain, Somnath BanerjeeLeicester Royal Infirmary, Leicester, UKIntroduction: Densiron® 68 is a high-density liquid used to tamponade inferior retinal detachments. We present a case series of 12 patients treated with Densiron as an intraocular tamponade agent.Methods: A retrospective analysis of 12 eyes in 12 patients was carried out. The primary endpoint was anatomic reattachment of the retina following removal of Densiron oil.Results: All patients had inferior detachments; 33% had associated proliferative vitreoretinopathy (PVR. Densiron was utilized as a primary agent in five patients (42%; the remaining patients had prior unsuccessful surgery for retinal reattachment, including pars plana vitrectomy, cryotherapy, laser, encirclement, gas (C3F8 or C2F6, or silicone oil. Eleven patients (91% had successful reattachment of the retina at 3 months following removal of Densiron; one patient had extensive PVR, total retinal detachment, preretinal macula fibrosis, and chronic hypotony, and surgical intervention was unsuccessful. Six patients (50% had raised intraocular pressure (IOP, resolving in the majority of cases following Densiron removal; two patients had long-term raised IOP requiring topical or surgical therapy. Of the six phakic patients, 50% developed significant cataract in the operated eye. Of those with successful retinal reattachment, visual outcome was variable, with 36% patients gaining two to four lines on Snellen, 27% remaining objectively the same, and 36% losing one to two lines.Conclusion: The anatomic success rate is high (91% in patients requiring Densiron tamponade for inferior retinal detachments with or without evidence of PVR either as a primary or secondary intervention. A common complication is raised IOP; however, this most often resolves following removal of the oil.Keywords: intraocular tamponade, silicone oil, retinal detachment, retinal reattachments

  10. [Reliable UV-light protection in intraocular lenses--scientific rationale and quality requirements].

    Science.gov (United States)

    Augustin, A J

    2014-09-01

    Since the late 1980s implantation of UV-blocker intraocular lenses during cataract surgery has become an internationally accepted standard. Last year the Kassenärztliche Vereinigung Bayern (KVB) and statutory health insurance organisations proposed for the first time quality criteria for intraocular lenses (IOL), thereby including exact parameters for the amount of UV light transmission (≤10% at 400 nm). Since then, the discussion has been raised again as to what extent IOLs should filter or block UV light. In this article, exact definitions of spectral subbands within the optical radiation band are given. Today, 400 nm is the internationally accepted standard to distinguish UV light and visible light. Moreover, exposure of the eye to UV radiation is described as well as mechanisms of photooxidative damage to the retina. Comprehensive laboratory and animal experimental studies show that light of short wave lengths, i.e., above all UV light but also blue light, may induce photochemical damage to the retina. Primary sites of such damage are both the outer segments of the photoreceptors and the retinal pigment epithelium (RPE). Physiological protective mechanisms of the eye, such as filtering properties of different ocular media are described in detail. Cornea, aqueous and vitreous absorb UV radiation below 300 nm, while the natural adult lens absorbs UV radiation between 300 and 400 nm. This protection is lost when the lens is removed by cataract surgery and thus should be restored. UV light does not contribute to vision but damages retinal structures. Therefore, UV-blocking intraocular lenses with a 10% cut-off near 400 nm should be implanted during cataract surgery. This ensures sufficient retinal protection after surgery. These theoretical considerations are supported by results from animal and clinical studies. Georg Thieme Verlag KG Stuttgart · New York.

  11. Iris-claw intraocular lenses to correct aphakia in the absence of capsule support.

    Science.gov (United States)

    De Silva, Samantha R; Arun, Kikkeri; Anandan, Maghizh; Glover, Nicholas; Patel, Chetan K; Rosen, Paul

    2011-09-01

    To evaluate the indications, postoperative visual efficacy, and complication rate after intraocular implantation of an iris-claw aphakic intraocular lens (IOL). Oxford Eye Hospital, Oxford, United Kingdom. Case series. This chart review comprised eyes with no capsule support that had anterior iris-fixation IOL implantation for aphakia between 2001 and 2009. The study comprised 116 eyes (104 patients). Iris-claw IOLs were inserted during primary lens surgery in 18 eyes (15.5%), during an IOL exchange procedure for dislocated posterior chamber IOLs in 19 eyes (16.4%), and as a secondary procedure in 79 eyes (68.1%). The mean follow-up was 22.4 months (range 3 to 79 months). The final corrected distance visual acuity (CDVA) was 6/12 or better in 68.9% of all eyes and in 47 of 53 eyes (88.7%) with no preoperative comorbidity. Complications included wound leak requiring resuturing in 2.6% of eyes, postoperative intraocular pressure rise in 9.5% of eyes (glaucoma escalation 0.8%), and cystoid macular edema in 7.7% of eyes (0.8% chronic). Iris-claw IOL subluxation occurred in 6.0% of eyes from 5 days to 60 months postoperatively; all the IOLs were repositioned. Corneal decompensation occurred in 1.7% of eyes; 0.8% had retinal detachments. Iris-claw IOL implantation for aphakia gave a good visual outcome and can be used for a wide range of indications. Postoperative complication rates were comparable to, if not better than, those with conventional anterior chamber IOLs. Correct implantation technique is critical in avoiding postoperative IOL subluxation. Copyright © 2011 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  12. Evaluation of the diurnal intraocular pressure fluctuations and blood pressure under dehydration due to fasting

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    Gonen Baser

    2016-12-01

    Full Text Available Introduction: This study aimed to investigate the diurnal intraocular pressure fluctuations under dehydration conditions and the relationship between the intraocular pressure fluctuations and blood pressure. Methods: The intraocular pressures (IOP, body weights, as well as systolic and diastolic blood pressures (SBP, DBP of 36 fasting healthy volunteers were recorded at 8:00 a.m. and 5:00 p.m. in the Ramadan of 2014 and two weeks after it. The data were analyzed using paired Student’s t-test and Pearson correlation analysis. Results: As the results demonstrated, the mean diurnal IOP differences of IOP, SBP, DBP, and weight were 2.67±1.33 mmHg, 9.44±8.02 mmHg, 3.33±5.94 mmHg, and 0.90±0.46 kg during the fasting period, respectively. In addition, the mean diurnal IOP differences of IOP, SBP, DBP, and weight were -0.33±1.4 mmHg (P=0.001, 0.55±7.25mmHg (P=0.003, -3.33±5.94 mmHg (P=0.001, and 0.12±0.45 kg (P=0.001 during the control period, respectively. There was a moderate correlation between the diurnal IOP and SBP differences (r=0.517, P=0.028. Conclusion: Based on the findings of the current study, the total fluid volume might have a more dominant effect on IOP peaks than the sympathetic system activity. Furthermore, the SBP was found to correlate with the IOP.

  13. Phacoemulsification with primary implantation of an intraocular lens in patients with uveitis

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    Pålsson S

    2017-08-01

    Full Text Available Sara Pålsson,1,2 Marita Andersson Grönlund,1,2 Dragana Skiljic,1,2 Madeleine Zetterberg1,2 1Department of Clinical Neuroscience/Ophthalmology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; 2Department of Ophthalmology, Sahlgrenska University Hospital, Mölndal, Sweden Purpose: To evaluate the outcome of cataract surgery in adult patients with uveitis. Materials and methods: In this retrospective cohort study, medical charts of patients with uveitis and matched control patients without uveitis who underwent cataract surgery at the Eye Clinic, Sahlgrenska University Hospital, Mölndal, between January 2005 and December 2009 were analyzed. Results: The study included 58 eyes with and 283 eyes without uveitis. The most common etiologies were idiopathic anterior uveitis and Fuchs’ heterochromic uveitis. Postoperative visual acuity at 4 weeks was ≥0.5 decimal (0.3 logMAR in 48 eyes with uveitis (87.3% compared to 180 non-uveitic eyes (86.1%. Four eyes with uveitis (7.1% and one eye without uveitis (0.5% developed postoperative intraocular hypertension/glaucoma. Posterior capsule opacification developed in 11 eyes (19.0% with and 28 eyes (12.4% without uveitis. Conclusion: With appropriate perioperative anti-inflammatory regimen and surveillance, modern cataract surgery using phacoemulsification and primary intraocular lens implantation can be performed in patients with uveitis without greater risk of complications, yielding similar visual outcome as in patients without uveitis. Keywords: cataract, intraocular lens, phacoemulsification, uveitis

  14. Time course of optical quality and intraocular scattering after refractive lenticule extraction.

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    Kazutaka Kamiya

    Full Text Available PURPOSE: To assess the time course of optical quality and intraocular scattering in relation to visual acuity after femtosecond lenticule extraction (FLEx for the correction of myopia. METHODS: This study evaluated 36 eyes of 36 patients with spherical equivalents of -4.38±1.53 D [mean ± standard deviation] who underwent FLEx. Before surgery, and 1 week and 1, 3 and 6 months after surgery, we assessed the modulation transfer function (MTF cutoff frequency, Strehl ratio, objective scattering index (OSI, and OQAS values (OVs, using a double-pass instrument. We also investigated the relationship of the OSI with corrected distance visual acuity (CDVA preoperatively and postoperatively. RESULTS: The mean changes in MTF cutoff frequency, Strehl ratio, OSI, OV100%, OV20%, and OV9% preoperatively and 6 months postoperatively were -5.51 ± 15.01, -0.03 ± 0.07, 0.35 ± 0.83, -0.17 ± 0.48, -0.14 ± 0.38, and -0.09 ± 0.22, respectively. We found no significant preoperative correlation between the OSI and logMAR CDVA (Spearman rank correlation coefficient r = 0.068, p = 0.69, and modest, but significant correlations 1 week and 1, 3, and 6 months postoperatively (r = 0.572, r = 0.562, r = 0.542, r = 0.540, p<0.001, respectively. CONCLUSIONS: FLEx induced a transient decrease in optical quality in association with an increase in intraocular scattering in the early postoperative period, possibly due to mild interface haze formation, but gradually recovered with time. It is suggested that this transient degradation in optical quality related to an increase in the intraocular scattering may result in a slight delay of CDVA recovery in the early postoperative period.

  15. Intra- and Intersession Repeatability of an Optical Quality and Intraocular Scattering Measurement System in Children.

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    Mi Tian

    Full Text Available To evaluate intra- and intersession repeatability of objective optical quality and intraocular scattering measurements with a double-pass system in children.Forty-two eyes of 42 children were included in the study. An optical quality analysis system (OQAS was used to measure optical quality parameters, including modulation transfer function cutoff frequency (MTFcutoff, Strehl ratio (SR, OQAS values (OV at 3 different contrasts and objective scatter index (OSI. Three measurement sessions with 10-min intervals were operated by the same technician, and in each session four consecutive measurements were obtained.Mean values for MTFcutoff, SR and OSI were 46.85 ± 7.45cpd, 0.27 ± 0.06 and 0.34 ± 0.22 respectively. 1 The intraclass correlation coefficients were ranged from 0.89 to 0.97 and coefficients of variation from 0.06 to 0.16 for all the parameters in the first session; the relative repeatability were 11.1% (MTFcutoff, 22.5% (SR, 10.9% (OV100%, 16.6% (OV2%, 22.4% (OV9% and 56.3% (OSI. Similar results were found in the second and third sessions. 2 Bland-Altman analysis showed that narrow 95% confidence intervals (compared between the first and second sessions ranged from -5.42 to 5.28 (MTFcutoff, -0.05 to 0.07 (SR, -0.18 to 0.18 (OV100%, -0.26 to 0.29 (OV20%, -0.33 to 0.39 (OV9% and -0.11 to 0.09 (OSI; the comparison between any two of the three sessions showed similar results.Measurements of optical quality and intraocular scattering in children by the double-pass system showed good intra- and intersession repeatability. Retinal image quality is high and intraocular scattering is low in children.

  16. Oculab Tono-Pen, Goldmann applanation tonometry, and pneumatic tonometry for intraocular pressure assessment in gas-filled eyes.

    Science.gov (United States)

    Hines, M W; Jost, B F; Fogelman, K L

    1988-08-15

    We performed 84 intraocular pressure measurements with the Oculab Tono-Pen, Goldmann applanation tonometer, and pneumatic tonometer in 47 eyes that had undergone pars plana vitrectomy and gas-fluid exchange. Measurements made by using the Tono-Pen were accurate when compared to those made by Goldmann tonometry (mean difference, 0.74 mm Hg). In a subset of eyes with increased intraocular pressure (greater than or equal to 25 mm Hg), the Tono-Pen provided measurements similar to those made by Goldmann applanation tonometry (P greater than .60), with only three of 39 readings (8%) underestimating the Goldmann pressure by more than 3 mm Hg. Pneumatic tonometry significantly underestimated the intraocular pressure in eyes with increased pressure (P less than .001), with 20 of 39 readings (51%) underestimating the Goldmann pressure by 5 mm Hg or more.

  17. Placement of a crystalline lens and intraocular lens: Retinal image quality.

    Science.gov (United States)

    Siedlecki, Damian; Nowak, Jerzy; Zajac, Marek

    2006-01-01

    The influence of changes of both crystalline lens and intraocular lens (IOL) misalignment on the retinal image quality was investigated. The optical model of the eye used in investigations was the Liou-Brennan model, which is commonly considered as one of the most anatomically accurate. The original crystalline lens from this model was replaced with an IOL, made of rigid polymethylmethacrylate, in a way that recommend obligatory procedures. The modifications that were made both for crystalline lens and IOL were the longitudinal, the transversal, and the angular displacement.

  18. Correlating intraocular pressure, blood pressure, and heart rate changes after jogging.

    Science.gov (United States)

    Karabatakis, V E; Natsis, K I; Chatzibalis, T E; Lake, S L; Bisbas, I T; Kallinderis, K A; Stangos, N T

    2004-01-01

    To examine the effects of jogging on intraocular pressure (IOP), blood pressure (BP), and heart rate (HR). Twenty-nine healthy individuals-25 athletes and 4 untrained-were studied. IOP, systolic and diastolic BP, and HR were measured before and just after 20 minutes of jogging (submaximal--70%--aerobic exercise). IOP decreased after jogging. Only three individuals had unchanged IOP in one eye and one individual in both eyes. The IOP decrease (1 to 8 mmHg) was statistically significant (pjogging (systolic: 0 to 60 mmHg, statistically significant changes, pjogging. Changes in BP and HR values have no linear quantitative correlation with IOP decrease.

  19. Ultraviolet or blue-filtering intraocular lenses: what is the evidence?

    Science.gov (United States)

    Downes, S M

    2016-01-01

    Cataract surgery was revolutionised by the introduction of modern intraocular lenses in the late 1940's. By the late 1960's to 1970's evidence had emerged that short-wavelength light caused phototoxicity at the retina and retinal pigment epithelium. By the early 1980's ultraviolet filters had been incorporated into intraocular lenses. This caused intense controversy, as there was concern that the UV-filtering chromophore might leach out into the eye causing toxicity. With the arrival of blue-filtering intraocular lenses (BFIOLs) in 1990's, a further debate was ignited as to their safety and potential disadvantages. Selecting the optimal performing intraocular lens to obtain the best visual performance with the fewest potential drawbacks has become complex and challenging for cataract surgeons and their patients with the wide choice of lenses available. Choosing a personalised lens to address astigmatism, presbyopia, spherical aberration, chromatic aberration, and potentially to shield the retina from short-wavelength light is now possible. The potential benefits and possible side effects of these different innovations emphasise the importance of assessing the evidence for their clinical utility, allowing the surgeon and the patient to weigh-up the risk benefit ratio and make an informed decision. The BFIOLs were developed to reduce cyanopsia, address chromatic aberration, and improve contrast sensitivity in different lighting conditions, as well as to prevent short-wavelength light reaching the retina thus potentially reducing the risk of developing age-related macular degeneration. Further design development of the BFIOLs was to mimic the natural crystalline lens absorption and transmittance properties in adulthood. Multiple publications have reported on the potential benefits and pitfalls of implanting a blue-filtering lens. The potential disadvantages raised in the literature over the last 25 years since their introduction, regarding compromise of visual

  20. Recent decreasing frequency of enucleation for intraocular retinoblastoma in Upper Egypt

    International Nuclear Information System (INIS)

    Abdallh, A.M.

    2006-01-01

    To evaluate the efficacy of combined systematic chemotherapy (chemoreduction) and local ophthalmic therapy (LT) is preventing or delaying external beam radiotherapy (EBRT) and enucleation in patients with intraocular retinoblastoma. This was a prospective, nonrandomized, single-institution, clinical study. Twenty-eight patients (37 eyes) with newly diagnosed intraocular retinoblastoma were included in this study. Primary enucleation was performed for 7 eyes with advanced intraocular retinoblastoma at presentation before starting chemoreduction. Using Reese-Ellsworth (RE) staging for RB, the remaining 30 eyes were as follows: Two in group I, 3 in group II, 8 in group III, 7 in group IV, and 9 in group V. All the 30 eyes were initially treated with 6 cycles of chemoredution using vincristine, etoposide and carboplatin, repeated every three weeks. After total of 6 cycles, each tumor was re-evaluated decide on the next mode of therapy. In cases where the tumor was reduced enough, LT (Thermotherapy, or cryotherapy, but plaque radiotherapy was unavailable) was applied. In cases where the tumor was reduced but insufficient for LT, we added another 3 cycles of same regimen in some patients; or we performed chemotherapy (CTT) for others, according to size of the residual tumor. Eyes failed to respond to tochemorduction and LT, received EBRT or were enucleated. Following 6 cycles of chemoreduction, all tumors showed an initial regression, and all vitreous and subretinal seeds showed calcification or disappearance of most of them. Among the 30 eyes, 12 eyes achieved complete response (CR), and 18 eyes achieved partial response (PR). Only 7 eyes (stage I to III) showed sufficient reduction of tumor size for the LT to be applied for, for which, TTT (4 eyes), and cryotherapy (3 eyes) were performed. Chemotherapy (CTT) was performed for 9 patients (13 eyes, 15 tumors). At the end of follow-up period, 14 of the total 30 eyes (46.7%) could not be salvaged with chemoreduction and LT

  1. Visual loss after use of intraocular silicone oil associated with thinning of inner retinal layers

    DEFF Research Database (Denmark)

    Christensen, Ulrik C; la Cour, Morten

    2012-01-01

    Purpose: To investigate the incidence and cause of severe visual loss following use and removal of intraocular silicone oil (SiO) after uncomplicated vitrectomy and SiO injection for primary rhegmatogenous retinal detachment (RRD). Methods: Consecutive case series of 216 patients operated...... visual acuity =6/12 before surgery, where SiO had been removed, cataract surgery performed and no re-detachment had occurred. Examinations included best-corrected visual acuity (BCVA) and high-definition optical coherence tomography (OCT) of the macular area. Results: Preoperative characteristics were...

  2. Primary anterior chamber intraocular lens for the treatment of severe crystalline lens subluxation.

    Science.gov (United States)

    Hoffman, Richard S; Fine, I Howard; Packer, Mark

    2009-10-01

    Subluxated cataractous and clear lenses are commonly treated by limbal or pars plana lensectomy followed by primary or secondary intraocular lens (IOL) implantation. Adjunctive capsular prosthetic devices have facilitated lens removal and IOL centration in these challenging cases but have also added complexity and potential complications to the procedure. Although crystalline lens extraction may be required to clear the visual axis in mild to moderate lens subluxations, we propose insertion of a primary anterior chamber IOL without lens extraction in severe subluxations when the eye is optically aphakic or can be made functionally aphakic following neodymium:YAG laser zonulysis. Two cases demonstrating this approach are presented.

  3. Retropupillary iris-claw intraocular lens in ectopia lentis in Marfan syndrome

    Directory of Open Access Journals (Sweden)

    Faria MY

    2016-06-01

    Full Text Available Mun Yueh Faria,1 Nuno Ferreira,2 Eliana Neto,1 1Vitreo Retinal Department, 2Ophthalmology Department, Santa Maria Hospital, Lisbon, Portugal Objective: To report visual outcomes, complication rate, and safety of retropupillary iris-claw intraocular lens (ICIOL in ectopia lentis in Marfan syndrome (MFS. Design: Retrospective study. Methods: Six eyes of three MFS patients with ectopia lentis underwent surgery for subluxation lens and retropupillary ICIOL implantation from October 2014 to October 2015 at the Department of Ophthalmology, Santa Maria Hospital in Lisbon, Portugal. Demographics, preoperative and postoperative best-corrected visual acuity (BCVA, and intraocular pressure were evaluated. Endothelium cell count was assessed using specular microscopy; anterior chamber depth was measured using Pentacam postoperatively; and intraocular lens position was viewed by ultrasound biomicroscopy. All patients were female; mean age was 20±14.264 years (range: 7–38 years. Results: The average follow-up period was 6.66 months (range: 4–16 months. Preoperative BCVA was 0.568±0.149 logMAR units, and postoperative BCVA was 0.066±0.121 logMAR units. The mean BCVA gain was –0.502±0.221 on the logMAR scale. Postoperative average astigmatism and intraocular pressure were 1.292±0.697 mmHg (range: 0.5–2.25 mmHg and 16 mmHg (range: 12–18 mmHg, respectively. The average endothelial cell density decreased from 3,121±178 cells/mm2 before surgery to 2,835±533 cells/mm2 after surgery (measured at last follow-up visit and in the last follow-up, representing an average endothelial cell loss of 9.16%. Mean anterior chamber depth was 4.01 mm (±0.77 mm, as measured by Pentacam. No complications were found intra- or postoperatively in any of the six studied eyes. Conclusion: Retropupillary ICIOL implantation is a safe and effective procedure in the treatment of aphakia in MFS eyes, without capsular support after surgery for ectopia lens. The six eyes that

  4. Carbachol as miotic agent in intra-ocular lens implant surgery

    Directory of Open Access Journals (Sweden)

    Agarwal Jitendra

    1988-01-01

    Full Text Available The intra cameral use of 0.025% carbachol as a miotic agent in anterior chamber intraocular lens im-plant surgery us reported in 15 cases. Carbachol produced prompt and effective moisis and was found to be harmless and non-irritating to the anterior chamber structures. A rebound dialatation of the pipit was noticed in the post operative period in 3 of our first 5 cases where only carbachol was used. For prolonged miosis instillation of a more powerful miotic like pilocarpine is recommended at the completion of surgery:

  5. A comparison of visual outcomes in three different types of monofocal intraocular lenses

    OpenAIRE

    Shetty, Vijay; Haldipurkar, Suhas S; Gore, Rujuta; Dhamankar, Rita; Paik, Anirban; Setia, Maninder Singh

    2015-01-01

    AIM: To compare the visual outcomes (distance and near) in patients opting for three different types of monofocal intraocular lens (IOL) (Matrix Aurium, AcrySof single piece, and AcrySof IQ lens). METHODS: The present study is a cross-sectional analysis of secondary clinical data collected from 153 eyes (52 eyes in Matrix Aurium, 48 in AcrySof single piece, and 53 in AcrySof IQ group) undergoing cataract surgery (2011-2012). We compared near vision, distance vision, distance corrected nea...

  6. Opacificação tipo "snowflake" em lente intra-ocular de polimetilmetacrilato (PMMA)

    OpenAIRE

    Pereira,Fabiana Dalla Rosa; Lima,Vagner Loduca; Rehder,José Ricardo Carvalho Lima

    2011-01-01

    As lentes intraoculares têm sido utilizadas na reabilitação de pacientes submetidos à cirurgia de catarata desde 1959 com grande sucesso. Entretanto, alterações no biomaterial dessas lentes vêm sendo descritas nos últimos anos, diminuindo a acuidade visual dos pacientes anos depois da cirurgia. Este relato apresenta um caso de opacificação tipo "snowflake" em lente de polimetilmetacrilato, seguida de discussão sobre as principais características dessa alteração e indicação de retirada e troca...

  7. Effect of pegaptanib sodium 0.3 mg intravitreal injections (Macugen) in intraocular pressure

    DEFF Research Database (Denmark)

    Boyer, David S; Goldbaum, Mauro; Leys, Anita M

    2014-01-01

    OBJECTIVE: To assess the rate of pegaptanib-associated sustained intraocular pressure (IOP) elevation. METHODS: A posthoc analysis was conducted on all IOP measurements, except the immediate 30-min postinjection, from all subjects randomised to pegaptanib 0.3 mg or sham injections continuously in...... lowering medication added during the course of the study. No subject required glaucoma surgery. CONCLUSIONS: In V.I.S.I.O.N., after 2 years, there was no evidence of sustained IOP elevation associated with pegaptanib 0.3 mg use. TRIAL REGISTRATION NUMBER: NCT00321997....

  8. Intraocular Lens Dislocation after Cataract Surgery in Tambolaka, Southwest Sumba, Indonesia: A Case Report

    OpenAIRE

    Ratna Sitompul

    2018-01-01

    Intraocular lens (IOL) dislocation is a rare complication of cataract extraction requiring prompt surgery. This case report aims to raise awareness of such cases and the importance of post-surgery follow-up. A 58-year-old female patient was found with anterior IOL dislocation a week after phacoemulsification surgery in her right eye. Visual acuity of the right eye was 1/60 with ciliary injection and IOL dislocation to the anterior chamber of the right eye. The patient underwent surgery of the...

  9. La educación superior como eje del desarrollo

    Directory of Open Access Journals (Sweden)

    Benjamín Afanador Vargas

    2003-11-01

    Full Text Available Este documento analiza cómo ha sido la interacción entre la política educativa y las estrategiasde desarrollo en Colombia, a lo largo del siglo XX. Se presenta una revisión del estadoactual de la educación en Colombia, tanto a nivel de educación básica y media, como de laeducación superior. Para ello se toman tres criterios básicos que son la cobertura, la calidady la equidad en el acceso a la educación. Para el caso de la educación superior, se comparala oferta de cupos con la demanda existente, se clasifican los distintos segmentos en que sedivide la educación superior y se hace una breve reseña sobre el recurso humano con que secuenta en la educación superior colombiana. Así mismo, se expone una conceptualización delos retos que enfrenta la educación superior, sobretodo para lograr una cohesión de la sociedad,evitando que algunos de sus integrantes sean excluidos y permitiendo que todos losestamentos de la sociedad puedan compartir los mismos ideales y los consideren asequibles.Finalmente, se presentan unas conclusiones que se derivan del estudio y se proponen algunasrecomendaciones de política .

  10. Prevención y represión del crimen organizado en el Mercosur

    Directory of Open Access Journals (Sweden)

    Germán Aller

    2015-09-01

    Full Text Available No escapa a los orígenes del crimen organizado la constante aparición de la inmunidad e impunidad de buena parte de las organizaciones criminales debido a la imposibilidad de llevarlos a juicio ni ser detenidos gracias a los focos de corrupción de que se sirven. Dichocircuito de espúrea protección obedeceno sólo a la "compra" de conciencias de funcionarios del segmento represivo, sino también a políticas criminales del "silencio", sembrando el temor mediante actos de sangre y amenazas respecto de sus posibles captores orepresores. Por ello, puede afirmarse que se denota un proceso de macrodelincuencia integrado por personas denominadas delincuentes comunes, pero también empresarios del crimen, muchas veces vistos y considerados comopersonas honorables y rodeados por la camada de actos de corrupción necesarios para sustentar la estructura delincuencial (...Contenido: La organización criminal: una conducta histórica. Panorama internacional del crimenorganizado. Tratamiento normativo penal y procedimental del crimen organizado. Prevención social: una dimensión humana. Ideas finale

  11. Determinantes prognósticos em pacientes com síndrome coronariana aguda sem elevação do segmento ST

    Directory of Open Access Journals (Sweden)

    Jessica Carolina Matos D'Almeida Santos

    2013-05-01

    Full Text Available FUNDAMENTO: Em pacientes com Síndromes Coronarianas Agudas (SCA sem Supradesnivelamento do Segmento ST (SST, sugere-se que uma série de marcadores (células inflamatórias, hiperglicemia e função renal é capaz de identificar indivíduos com maior risco para eventos cardiovasculares. OBJETIVO: Avaliar o impacto desses parâmetros laboratoriais em desfechos intra-hospitalares de pacientes com SCA sem SST. MÉTODOS: Foram avaliados prospectivamente 195 pacientes admitidos consecutivamente com SCA sem SST. Foram registrados dados clínicos, demográficos e laboratoriais ao longo do período de internação no hospital, em relação à ocorrência ou não de eventos combinados. RESULTADOS: A idade média foi de 67 ± 12 anos, e 52% eram homens. Na análise da área sob a curva ROC, somente a razão neutrófilo/linfócito (AUC: 70%, IC95%: 56%-82%, p = 0,006 e a creatinina (AUC: 62%, IC95%: 50%-80%, p = 0,03 discriminaram aqueles pacientes com SCA sem SST que apresentaram algum desfecho. Os pacientes que sofreram algum evento adverso durante a internação apresentaram menores contagens de linfócitos (1502 ± 731 / mm³ vs. 2020 ± 862 / mm³; p = 0,002, menores taxas de filtração glomerular (51 ± 27 mL/min vs. 77±34 mL/min; p < 0,001 e maiores níveis séricos de creatinina (2,1 ± 2,7 mg/dL vs. 1,1 ± 1,3 mg/dL; p = 0,047 do que aqueles que tiveram uma hospitalização sem intercorrências. A análise de regressão logística demonstrou que as variáveis que permaneceram como preditores independentes e significativos foram: taxa de filtração glomerular (OR: 1,03; IC95%: 1,00-1,13; p = 0,002, e contagem de linfócitos (OR: 1,02; IC95%: 1,01-1,04; p = 0,03. CONCLUSÃO: A avaliação da função renal e a contagem de linfócitos fornecem uma informação potencialmente útil para a estratificação prognóstica em doentes com SCA sem SST.

  12. [Possibility of 3D Printing in Ophthalmology - First Experiences by Stereotactic Radiosurgery Planning Scheme of Intraocular Tumor].

    Science.gov (United States)

    Furdová, A; Furdová, Ad; Thurzo, A; Šramka, M; Chorvát, M; Králik, G

    Nowadays 3D printing allows us to create physical objects on the basis of digital data. Thanks to its rapid development the use enormously increased in medicine too. Its creations facilitate surgical planning processes, education and research in context of organ transplantation, individualization prostheses, breast forms, and others.Our article describes the wide range of applied 3D printing technology possibilities in ophthalmology. It is focusing on innovative implementation of eye tumors treatment planning in stereotactic radiosurgery irradiation.We analyze our first experience with 3D printing model of the eye in intraocular tumor planning stereotactic radiosurgery. 3D printing, model, Fused Deposition Modelling, stereotactic radiosurgery, prostheses, intraocular tumor.

  13. Cryopreserved tracheal segments: a new tool for bench surgical training in thoracic surgery Segmentos criopreservados de traqueia: uma nova ferramenta para auxiliar o treinamento na cirurgia torácica

    Directory of Open Access Journals (Sweden)

    Avelina Sotres-Vega

    2012-08-01

    Full Text Available PURPOSE: To present a new low-cost high fidelity bench model of cryopreserved trachea that can be used to learn surgical skills from medical students to cardiothoracic surgery fellows. METHODS: Ten tracheas were harvested from ten non-trachea related research dogs at the moment of euthanasia. Each trachea was trimmed in six or seven rings segments. They were cryopreserved and stored during 60 days. The day programmed for surgical skills practice, they were thawed to room temperature. RESULTS: Forty segments have been used. After defrosting, all the segments kept their normal anatomic shape and structural integrity. Two incisions were made on every tracheal segment and sutured with running or separate stitches with 5-0 polypropilene. There were no complications such as cartilage ruptures, neither tears on the mucosae, the cartilages nor the membranous posterior membrane. CONCLUSIONS: The cryopreserved trachea is a high fidelity, practical, reproducible, portable, low-cost bench model. It allows cardiothoracic fellows to learn how to handle a trachea, as well as to perfect their surgical and suture abilities before applying them on a real patient's trachea.OBJETIVO: Apresentar novo modelo de traquéia criopreservada de baixo custo e alta fidelidade que pode ser usado tanto por estudantes de medicina como por cirurgiões cardiotorácicos no aprendizado e desenvolvimento de suas habilidades cirúrgicas. MÉTODOS: Foram coletados amostras de dez traquéias de dez cães utilizados para pesquisa após a eutanásia. Cada segmento de traquéia foi dividida em seis ou sete anéis, criopreservadas e armazenadas durante 60 dias. No dia programado para a prática cirúrgica os segmentos foram descongelados a temperatura ambiente. RESULTADOS: Foram utilizados 40 segmentos no estudo. Após o descongelamento todos os segmentos mantiveram sua forma anatômica e sua integridade estrutural. Foram realizadas duas incisões em cada segmento traqueal que foram

  14. Avaliação do segmento venoso femoropoplíteo pela ultrassonografia Doppler em pacientes com úlcera varicosa Doppler ultrasonography of the femoral popliteal segment in patients with venous ulcer

    Directory of Open Access Journals (Sweden)

    Jesus Antonio de Carvalho Abreu

    2012-12-01

    Full Text Available CONTEXTO: Como a úlcera é uma grave complicação da insuficiência venosa crônica, é necessário o conhecimento amplo de sua fisiopatologia. A ultrassonografia Doppler venosa é o exame complementar mais adequado, que possibilita o estudo do sistema venoso superficial e profundo, sua anatomia e fisiologia. Trabalhos recentes valorizam o refluxo em Veia Poplítea como importante fator para o desenvolvimento deste quadro clínico. OBJETIVOS: Avaliar o refluxo em segmento venoso femoropoplíteo em pacientes com úlcera varicosa. TIPO DE ESTUDO: Estudo de prevalência. MÉTODOS: Cento e quatro pacientes apresentando 118 membros inferiores com úlcera varicosa. Procedimentos: exame de ultrassonografia Doppler venosa do membro acometido, observado o refluxo no segmento venoso femoropoplíteo e diâmetro da Veia Poplítea. Variáveis: Primária: refluxo no segmento venoso femoropoplíteo. Secundária: diâmetro da Veia Poplítea. RESULTADOS: A presença de refluxo no segmento venoso femoropoplíteo foi observada em 56 (47,45% dos 118 membros com úlcera varicosa, examinados em 104 pacientes. O diâmetro médio da Veia Poplítea foi de 1,14 cm, sendo o diâmetro médio normal da população 0,6 cm. CONCLUSÃO: O refluxo venoso no segmento venoso femoropoplíteo é um importante fator na avaliação do prognóstico destes pacientes, o aumento de diâmetro da Veia Poplítea reflete a magnitude da insuficiência venosa.BACKGROUND: Ulcer is a severe complication from chronic venous insufficiency; thus, its pathophysiology needs to be deeply understood. Venous Doppler ultrasonography is the most appropriate complementary imaging study, enabling the study of the superficial and deep venous system, the diameter and flow of the veins. Recent studies have suggested that popliteal vein reflux is an important factor for the development of ulceration. OBJECTIVE: To evaluate the venous reflux of the femoral popliteal segment in patients with venous ulcers

  15. Intermediate-term and long-term outcome of piggyback drainage: connecting glaucoma drainage device to a device in-situ for improved intraocular pressure control.

    Science.gov (United States)

    Dervan, Edward; Lee, Edward; Giubilato, Antonio; Khanam, Tina; Maghsoudlou, Panayiotis; Morgan, William H

    2017-11-01

    This study provides results of a treatment option for patients with failed primary glaucoma drainage device. The study aimed to describe and evaluate the long-term intraocular pressure control and complications of a new technique joining a second glaucoma drainage device directly to an existing glaucoma drainage device termed 'piggyback drainage'. This is a retrospective, interventional cohort study. Eighteen eyes of 17 patients who underwent piggyback drainage between 2004 and 2013 inclusive have been studied. All patients had prior glaucoma drainage device with uncontrolled intraocular pressure. The piggyback technique involved suturing a Baerveldt (250 or 350 mm) or Molteno3 glaucoma drainage device to an unused scleral quadrant and connecting the silicone tube to the primary plate bleb. Failure of intraocular pressure control defined as an intraocular pressure greater than 21 mmHg on maximal therapy on two separate occasions or further intervention to control intraocular pressure. The intraocular pressure was controlled in seven eyes (39%) at last follow-up with a mean follow-up time of 74.2 months. The mean preoperative intraocular pressure was 27.1 mmHg (95% confidence interval 23.8-30.3) compared with 18.4 mmHg (95% confidence interval 13.9-22.8) at last follow-up. The mean time to failure was 57.1 months (95% confidence interval 32.2-82), and the mean time to further surgery was 72.3 months (95% confidence interval 49.9-94.7). Lower preoperative intraocular pressure was associated with longer duration of intraocular pressure control (P = 0.048). If the intraocular pressure was controlled over 2 years, it continued to be controlled over the long term. Two eyes (11%) experienced corneal decompensation. Piggyback drainage represents a viable surgical alternative for the treatment of patients with severe glaucoma with failing primary glaucoma drainage device, particularly in those at high risk of corneal decompensation. © 2017 Royal Australian and New Zealand

  16. Las características del adulto mayor peruano y las políticas de protección social

    OpenAIRE

    Javier Olivera; Jhonatan Clausen

    2013-01-01

    El presente documento busca, en primer lugar, realizar una caracterización de las condiciones socioeconómicas de la población de adultos mayores en el Perú con énfasis en la situación de pobreza y desprotección social de este segmento de población. El análisis de la Encueta Nacional de Hogares (Enaho) 2011 revela que la mayor cantidad de personas mayores de 65 años que se encuentran en situación de extrema pobreza residen en la sierra rural. Del mismo modo, se observa que únicamente el 1% de ...

  17. Intraocular pressure and Schirmer tear test values in maned wolf (Chrysocyon brachyurus

    Directory of Open Access Journals (Sweden)

    Cristiane S. Honsho

    Full Text Available Abstract: The purpose of this study was to establish baseline data on lacrimal quantity (STT-1 and intraocular pressure (IOP in captive maned wolves. Ten healthy adult maned wolves were contained with a snare pole and muzzle and kept in decubitus of the left side. STT-1 measurement was performed on the lateral third of the lower conjunctival sac for one minute. The cornea was desensitized and intraocular pressure was measured with an tonopen. Average STT-1 in both eyes was 11±5mm.min-1, with no statistical difference between the left and right eye (p=0.960. Average IOP in both eyes was 20±6mmHg, with no statistical difference between the left and right eye (p=0.836. Average STT-1 was lower than, and IOP was the same as normal levels found in dogs. There was no statistical difference in the age of the animals, and STT-1 and IOP values. In the present paper, average maned wolf STT-1 levels were lower compared with those found in dogs, while the IOP was the same in maned wolves as in dogs. Due to the increased incidence in providing emergency care for maned wolf victims of road kill and fires, determination reference values of ocular parameters may improve the correct diagnosis and treatment of the disease.

  18. Customized toric intraocular lens implantation for correction of extreme corneal astigmatism due to corneal scarring

    Directory of Open Access Journals (Sweden)

    R Bassily

    2010-03-01

    Full Text Available R Bassily, J LuckOphthalmology Department, Royal United Hospital, Combe Park, Bath, UKAbstract: A 76-year-old woman presented with decreased visual function due to cataract formation. Twenty-five years prior she developed right sided corneal ulceration that left her with 10.8 diopters (D of irregular astigmatism at 71.8° (steep axis. Her uncorrected visual acuity was 6/24 and could only ever wear a balanced lens due to the high cylindrical error. Cataract surgery was planned with a custom designed toric intraocular lens (IOL with +16.0 D sphere inserted via a wound at the steep axis of corneal astigmatism. Postoperative refraction was -0.75/+1.50 × 177° with a visual acuity of 6/9 that has remained unchanged at six-week follow-up with no IOL rotation. This case demonstrates the value of high power toric IOLs for the correction of pathological corneal astigmatism.Keywords: intraocular lens, corneal ulceration, visual acuity, scarring

  19. Factors associated with strabismus after cataract extraction and primary intraocular lens implantation in congenital cataracts

    Directory of Open Access Journals (Sweden)

    Soo Jung Lee

    2014-06-01

    Full Text Available AIM: To evaluate factors associated with the development of strabismus after cataract extraction and primary intraocular lens implantation.METHODS: The medical records of 122 patients, aged 1.5mo to 9y, who had undergone cataract extraction with primary intraocular lens implantation between January 1993 and August 2011 were reviewed. Fourteen patients (17 eyes with strabismus before cataract surgery were excluded. Patients were divided into those with congenital bilateral cataracts (64 patients, 128 eyes and those with unilateral cataracts (44 patients, 44 eyes. The associations between the development of strabismus and age at cataract surgery, pre- and post-cataract extraction corrected distance visual acuity (CDVA, interocular CDVA difference, nystagmus, surgical method, and secondary cataract were evaluated.RESULTS: Factors significantly associated with the development of strabismus included age at cataract surgery (≤1y, preoperative mean CDVA ≤20/100, presence of nystagmus in the bilateral cataract group and postoperative interocular CDVA difference >20/70 in the unilateral group. Postoperative CDVA ≤20/100 and preservation of posterior capsule, and presence of secondary cataract were significant factors in both groups.CONCLUSION: Children with congenital cataracts should be monitored carefully after cataract surgery for the development of strabismus, especially when they underwent surgery at age ≤1y, and they have nystagmus, large postoperative interocular CDVA difference, poor preoperative and postoperative CDVA, preservation of the posterior capsule, or secondary cataract.

  20. A fully intraocular high-density self-calibrating epiretinal prosthesis.

    Science.gov (United States)

    Monge, Manuel; Raj, Mayank; Nazari, Meisam Honarvar; Chang, Han-Chieh; Zhao, Yu; Weiland, James D; Humayun, Mark S; Tai, Yu-Chong; Emami, Azita

    2013-12-01

    This paper presents a fully intraocular self-calibrating epiretinal prosthesis with 512 independent channels in 65 nm CMOS. A novel digital calibration technique matches the biphasic currents of each channel independently while the calibration circuitry is shared among every 4 channels. Dual-band telemetry for power and data with on-chip rectifier and clock recovery reduces the number of off-chip components. The rectifier utilizes unidirectional switches to prevent reverse conduction loss in the power transistors and achieves an efficiency > 80%. The data telemetry implements a phase-shift keying (PSK) modulation scheme and supports data rates up to 20 Mb/s. The system occupies an area of 4.5 ×3.1 mm². It features a pixel size of 0.0169 mm² and arbitrary waveform generation per channel. In vitro measurements performed on a Pt/Ir concentric bipolar electrode in phosphate buffered saline (PBS) are presented. A statistical measurement over 40 channels from 5 different chips shows a current mismatch with μ = 1.12 μA and σ = 0.53 μA. The chip is integrated with flexible MEMS origami coils and parylene substrate to provide a fully intraocular implant.

  1. Retropupillary iris-claw intraocular lens for the surgical correction of aphakia in cases with microspherophakia

    Directory of Open Access Journals (Sweden)

    Sameh Mosaad Fouda

    2016-01-01

    Full Text Available Purpose: This study aimed to evaluate the safety and efficacy of retropupillary fixation of an iris-claw intraocular lens (IOL; Verisyse polymethyl methacrylate IOL, Abbott Medical Optics [AMO], Netherlands for the surgical correction of aphakia in microspherophakic eyes without sufficient capsular support. Design: This was a prospective, interventional, noncomparative case series. Methods: This interventional case series comprised 17 eyes of 9 microspherophakic patients. Retropupillary fixation of the Verisyse iris-claw IOL (AMO was performed in all cases. The surgical time was measured. Corrected distance visual acuity, astigmatism, intraocular pressure (IOP, tissue reaction, pigment dispersion, and stability of the IOL were studied 1 day, 3 days, 1 week, 2 weeks, 1 month, and 6 months postoperatively. Results: Eight patients had familial microspherophakia and one patient had Marfan's syndrome. Eighty-two percent of the cases achieved a visual acuity of 0.3 or better. There was no significant postoperative inflammatory reaction. Transient elevation of IOP was recorded in two cases in the 1st week only. One IOL developed disengagement of one of the haptics from the iris and was successfully re-engaged. All the other IOLs were well centered and stable. The mean surgical time was 18.0 ± 4.5 min. Conclusions: Retropupillary fixation of an iris-claw IOL is a safe and effective procedure that provides early visual recovery. It is also a time-saving method for correcting aphakia in microspherophakic eyes without sufficient capsular support.

  2. Transscleral fixation of closed loop haptic acrylic posterior chamber intraocular lens in aphakic nonvitrectomized eyes

    Directory of Open Access Journals (Sweden)

    Siddharth Agrawal

    2015-01-01

    Full Text Available Purpose: To evaluate the outcome of transscleral fixation of closed loop haptic acrylic posterior chamber intraocular lens (PCIOL in aphakia in nonvitrectomized eyes. Materials and Methods: Patients with postcataract surgery aphakia, trauma with posterior capsule injury, subluxated crystalline lens, and per operative complications where sulcus implantation was not possible were included over a 1-year period. Scleral fixation of acrylic hydrophilic PCIOL was performed according to the described technique, and the patients were evaluated on the day 1, 3, 14, and at 3 and 12 months postoperatively for IOL centration, pseudophakodonesis, change in best-corrected visual acuity (BCVA, and any other complications. Results: Out of twenty-nine eyes of 24 patients, who completed the study, 25 (86.2% eyes had improved, 2 (6.9% eyes showed no change, and 2 (6.9% eyes had worsening of BCVA. Three (10.3% eyes developed postoperative complications. A significant improvement in mean BCVA (P < 0.0001 was observed after the procedure. Mean duration of follow-up was 26.2 months (range 22–35 months. Conclusion: The use of closed loop haptic acrylic IOL for scleral fixation appears to be safe and effective alternative to conventional scleral fixated polymethyl methacrylate intraocular lenses.

  3. Effects of intraocular irrigating solutions on the spreading of rabbit corneal endothelial cells on extracellular matrices.

    Science.gov (United States)

    Nishida, T; Otori, T

    1991-01-01

    The effects of four commercially available irrigating solutions on the spreading of rabbit corneal endothelial cells on various extracellular matrices were studied. Cultured rabbit corneal endothelial cells, suspended in one of the following intraocular irrigating solutions, Opeguard MA, BSS, BSS Plus, lactated Ringer solution (Lactec) or physiological saline, were placed on uncoated tissue culture plates or on plates coated with extracellular matrices (fibronectin, laminin, collagen type I, or collagen type IV). The cell area was measured after 45 minutes' incubation. The cells spread on all of the extracellular matrices examined but not on the uncoated tissue culture plates. On the fibronectin or laminin matrix, the cell area was significantly greater with Opeguard MA or BSS Plus. On laminin and collagen type IV, the cell area was the greatest with Opeguard MA. On collagen type I, the cell area was significantly greater with Opeguard MA, BSS, or BSS Plus. These results demonstrated that the rabbit corneal endothelial cells responded to the extracellular matrices, and that Opeguard MA or BSS Plus provided more favorable conditions for the spreading of these cells. These results indicated that both Opeguard MA and BSS Plus might aid the spreading of corneal endothelial cells during wound-healing immediately after intraocular surgery.

  4. Influence of co-payment levels on patient and surgeon acceptance of advanced technology intraocular lenses.

    Science.gov (United States)

    Carones, Francesco; Knorz, Michael C; Jackson, Daniel; Samiian, Ali

    2014-04-01

    To investigate patients' willingness to pay for advanced technology intraocular lenses and surgeons' willingness to recommend them. In this study, 370 cataract surgeons and 700 patients undergoing cataract surgery from seven countries underwent online interviews in which they were shown unbranded profiles of three advanced technology intraocular lenses (ie, biconvex toric aspheric optic, symmetric biconvex diffractive optic, and biconvex diffractive aspheric toric) and asked to indicate their willingness to accept (for patients) or suggest (for surgeons) each lens. Acceptance was assessed assuming there was either no co-payment or co-payments of €500 to €1,500 +15%. All three lenses were widely accepted by patients, with 68% to 99% indicating acceptance when there was no co-payment. In contrast, surgeons' willingness to suggest them was markedly lower (20% to 43%). Both patients' acceptance of the lenses and surgeons' willingness to suggest them decreased with increasing co-payment levels to 19% to 74% (patients) and 5% to 31% (surgeons) at the highest co-payment levels. There is a marked discrepancy between patients' acceptance of the three lenses and surgeons' willingness to suggest them. Although patients' acceptance is high, it decreases with increasing out-of-pocket expenditure. Manufacturers should communicate the relative benefits and costs of their lenses to both surgeons and patients. Copyright 2014, SLACK Incorporated.

  5. Suppressive effect of astaxanthin on retinal injury induced by elevated intraocular pressure.

    Science.gov (United States)

    Cort, Aysegul; Ozturk, Nihal; Akpinar, Deniz; Unal, Mustafa; Yucel, Gultekin; Ciftcioglu, Akif; Yargicoglu, Piraye; Aslan, Mutay

    2010-10-01

    The aim of this study was to clarify the possible protective effect of astaxanthin (ASX) on the retina in rats with elevated intraocular pressure (EIOP). Rats were randomly divided into two groups which received olive oil or 5mg/kg/day ASX for a period of 8 weeks. Elevated intraocular pressure was induced by unilaterally cauterizing three episcleral vessels and the unoperated eye served as control. At the end of the experimental period, neuroprotective effect of ASX was determined via electrophysiological measurements of visual evoked potentials (VEP) and rats were subsequently sacrificed to obtain enucleated globes which were divided into four groups including control, ASX treated, EIOP, EIOP+ASX treated. Retinoprotective properties of ASX were determined by evaluating retinal apoptosis, protein carbonyl levels and nitric oxide synthase-2 (NOS-2) expression. Latencies of all VEP components were significantly prolonged in EIOP and returned to control levels following ASX administration. When compared to controls, EIOP significantly increased retinal protein oxidation which returned to baseline levels in ASX treated EIOP group. NOS-2 expression determined by Western blot analysis and immunohistochemical staining was significantly greater in rats with EIOP compared to ASX and control groups. Retinal TUNEL staining showed apoptosis in all EIOP groups; however ASX treatment significantly decreased the percent of apoptotic cells when compared to non treated ocular hypertensive controls. The presented data confirm the role of oxidative injury in EIOP and highlight the protective effect of ASX in ocular hypertension. Copyright (c) 2010 Elsevier Inc. All rights reserved.

  6. Ultraviolet radiation at Mediterranean latitudes and protection efficacy of intraocular lenses.

    Science.gov (United States)

    Artigas, J M; Felipe, A; Navea, A; Artigas, C; Menezo, J L

    2013-01-01

    After determining the mean intensity of ultraviolet radiation to which the human eye is exposed at Mediterranean latitudes, this data is used to evaluate the efficacy of the ultraviolet filters incorporated into various intraocular lenses. Ultraviolet radiation measured at Mediterranean latitudes was used as a reference for the theoretical calculation of the amount of radiation to which the human eye is exposed. The spectral transmission curve from 290 to 380 nm was measured for 10 IOLs using a UV/VIS Perkins-Elmer Lambda 800 spectrometer. At Mediterranean latitudes, at sea level, with a mean annual solar irradiation of 50 j/cm(2), the human eye receives a quantity of UVA and UVB that is lower than the threshold toxic dose for the rabbit crystalline lens (93 j/cm(2) for UVA and 6.45 j/cm(2) for UVB). However, at higher altitudes and with albedo approaching 0.9 (fresh snow), the amount of radiation increases, with duration of exposure potentially playing a significant role. The UV filters incorporated into the IOLs studied are, in general, protective against such levels of radiation. At Mediterranean latitudes, at sea level, the amount of UV radiation to which our eyes are exposed is insufficient to damage the crystalline lens; however, at higher altitudes, the risk of such damage exists. UV filters incorporated into intraocular lenses are generally effective, since they filter all radiation with wavelengths under 380 nm. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

  7. Comparing the mode of action of intraocular lutein-based dyes with synthetic dyes.

    Science.gov (United States)

    Sousa-Martins, Diogo; Caseli, Luciano; Figueiredo, Mafalda C; Sa E Cunha, Claudia; Mota-Filipe, Helder; Souza-Lima, Acácio; Belfort, Rubens; Rodrigues, Eduardo; Maia, Mauricio

    2015-02-19

    To investigate and compare the mechanism by which lutein-based and synthetic intraocular dyes interact with their target membranes during ophthalmic surgeries. Surrogate membrane models were used in order to simulate the different intraocular membranes: internal limiting membrane (ILM), vitreous, anterior capsule (AC), and epiretinal membrane (ERM). Different lutein-based dyes, such as Phacodyne, Retidyne, Retidyne Plus, and Vitreodyne were tested, as well as Trypan Blue (TB), Indocyanine Green (ICG), Brilliant Blue (BB), and Triamcinolone Acetonide (TA). The interactions between the film components occurring at the air-water interface were investigated with surface pressure-area isotherms and polarization modulation infrared reflection-absorption spectroscopy (PM-IRRAS). With the exception of TA and ICG, none of the tested dyes revealed toxicity to the analyzed membranes. The interaction of TA with the vitreous model affected deeply the biointerface structure of the model. A significant condensation of the monolayer is noted when ICG contacted with ILM by the isotherms or even a solubilization of part of the monolayer toward the aqueous subphase. Retidyne Plus may provide the fluidization of the membrane, but maintains intact the structure of proteins present in the model. The present study demonstrates for the first time that lutein-based dyes interact through a physical mechanism of action with membrane models of structures present in human eye. On the other hand, the chemical interaction of synthetic dyes TA and ICG resulted in an alteration of the membrane models. Copyright 2015 The Association for Research in Vision and Ophthalmology, Inc.

  8. The diagnostic value of intraocular fluid analysis by polymerase chain reaction in Thai patients with uveitis.

    Science.gov (United States)

    Pathanapitoon, Kessara; Kongyai, Natedao; Sirirungsi, Wasna; de Groot-Mijnes, Jolanda D F; Leechanachai, Pranee; Choovuthayakorn, Janejit; Kunavisarut, Paradee; Rothova, Aniki

    2011-11-01

    Uveitis is a major cause of severe visual impairment throughout the world and can be initiated by various infectious and non-infectious causes. Early recognition of specific infections is important as the treatment with antimicrobial agents might stop the progression or even cure the eye disease. To determine the infectious causes of uveitis in Thailand, intraocular fluid samples of 100 HIV-negative patients and 47 HIV-positive patients with uveitis were examined using real-time PCR analysis for herpes simplex virus, varicella zoster virus, cytomegalovirus and Toxoplasma gondii. Positive PCR results were found in 33/100 (33%) HIV-negative patients and in 33/47 (70%) HIV-positive patients with uveitis. In Thailand, cytomegalovirus was identified as the most frequent cause of infectious uveitis in both HIV-negative and HIV-positive patients (49 and 91%, respectively). PCR analysis of intraocular samples in uveitis was a valuable diagnostic assay. The pattern of uveitis observed in the Far East differs from that found in the West. Copyright © 2011 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.

  9. Dosimetry and treatment planning of Occu-Prosta 125I seeds for intraocular lesions

    International Nuclear Information System (INIS)

    Chaudhari, Suresh; Deshpande, Sudesh; Anand, Vivek; De, Sandeep; Kannan, V.; Saxena, Sanjay; Dash, A.; Basu, Mahua; Samant, Preetam

    2008-01-01

    Intraocular malignant lesions are frequently encountered in clinical practice. Plaque brachytherapy represents an effective means of treatment for intraocular lesions. Recently Radiopharmaceutical Division, BARC, Mumbai, has indigenously fabricated reasonable-cost 125 I sources. Here we are presenting the preliminary experience of dosimetry of sources, configuration of treatment planning system (TPS) and quality assurance (QA) for eye plaque therapy with Occu-Prosta 125 I seeds, treated in our hospital, for a patient with ocular lesions. 125 I seeds were calibrated using well-type chamber. BrachyVision TPS was configured with Monte Carlo computed radial dose functions and anisotropy functions for 125 I sources. Dose calculated by TPS at different points in central axis and off axis was compared with manually calculated dose. Eye plaque was fabricated of 17 karat pure gold, locally. The seeds were arranged in an outer ring near the edge of the plaque and in concentric rings throughout the plaque. The sources were manually digitized on the TPS, and dose distribution was calculated in three dimensions. Measured activity using cross-calibrated well-type chamber was within ± 10% of the activity specified by the supplier. Difference in TPS-calculated dose and manually calculated dose was within 5%. Treatment time calculated by TPS was in concordance with published data for similar plaque arrangement. (author)

  10. Clinical observation of Artisan iris-clip intraocular lens implantation at stage Ⅰ

    Directory of Open Access Journals (Sweden)

    Qing Zhou

    2014-09-01

    Full Text Available AIM: To observe the clinical efficacy of Artisan iris-clip intraocular lens(IOLimplantation on cataract with a wide range of lens dislocation.METHODS: Twenty-four hospital patients(28 eyesof cataract with lens subluxation by trauma(20 patients, 20 eyesand Marfan's syndrome(4 patients, 8 eyesduring May 2007 to December 2011 were selected. All of them underwent phacoemulsification or an anterior vitrectomy and Artisan iris-clip IOL implantation at stage Ⅰ. Postoperative visual acuity, corneal endothelial cell count, intraocular lens position and postoperative complications were observed. Follow-up time was 6mo.RESULTS:Compared with the preoperative, postoperative best corrected visual acuity improved to varying degrees, visual acuity of 0.1-0.5 was in 20 eyes, 0.5-1.0 in 8 eyes. After followed up 1-6mo, no artificial lens shift, iris inflammation, iris atrophy and corneal decompensation and other complications were observed.CONCLUSION: Cataract surgery with a wide range of lens dislocation is difficult, but as long as surgeons who have a wealth of clinical experience and superb skills, still can carry out phacoemulsification surgery or anterior vitrectomy and Artisan iris-clip IOL implantation and obtain a better outcome.

  11. Comparison of decentration and tilt between one piece and three piece polymethyl methacrylate intraocular lenses

    Science.gov (United States)

    Hayashi, K.; Hayashi, H.; Nakao, F.; Hayashi, F.

    1998-01-01

    BACKGROUND—The extent of the decentration and tilt was prospectively compared between one piece polymethyl methacrylate (PMMA) and three piece PMMA intraocular lenses (IOLs) which were implanted in the capsular bag after performing continuous curvilinear capsulorhexis.
METHODS—91 patients underwent a one piece PMMA IOL implantation in one eye as well as the implantation of the three piece PMMA IOL with polyvinylidene fluoride loops in the opposite eye. The length of the lens decentration and the angle of the tilt were quantitated using the anterior eye segment analysis system (EAS-1000) at 1 week as well as 1, 3, and 6 months postoperatively.
RESULTS—The mean length of the decentration in the one piece IOL was smaller than that in the three piece IOL at 1 week (p=0.0092), 1 month (p=0.0044), 3 months (p=0.0069), and 6 months (p=0.0010) postoperatively. However, no significant difference was found in the degree of the tilt between the two types of IOLs throughout the observation periods.
CONCLUSION—These results clarified that the one piece PMMA IOL with rigid PMMA haptics implanted in the capsular bag provides a better centration than the three piece PMMA IOL with flexible haptics, whereas the tilt was the same between the two types of IOLs.

 Keywords: intraocular lens; decentration; tilt; continuous curvilinear capsulorhexis PMID:9640193

  12. Cap morphology after small-incision lenticule extraction and its effects on intraocular scattering

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    Dan Fu

    2018-03-01

    Full Text Available AIM: To investigate cap morphology after small-incision lenticule extraction (SMILE and its effects on intraocular scattering. METHODS: Sixty-five eyes of 33 patients undergoing SMILE were enrolled. In addition to regular evaluation, Fourier-domain optical coherence tomography was used to investigate cap thickness at 1d, 1wk, 1 and 3mo postoperatively. The optical quality including modulation transfer function cutoff frequency, Strehl ratio, Optical Quality Analysis System (OQAS values, and objective scattering index (OSI, were evaluated using OQASTM. RESULTS: Cap thickness decreased from 1d to 1wk (P<0.001, but remained higher than intended thickness of 120 μm after 3mo (P<0.001. Cap thickness in central area was thinner than that of in the paracentral and peripheral areas (P<0.0001. Total number of microdistortions decreased from 1d to 3mo (P<0.0001. Pearson analysis revealed a weak correlation between OSI and standard deviation of cap thickness at 1d and 1mo, as well as between range of cap thickness and OSI at 1mo. No correlation was found between microdistortion and OSI, but a negative correlation existed between microdistortion and range at 1d and 1moafter surgery. CONCLUSION: The corneal cap tends to be more accurate and regular with time lapse. Better cap morphology tends to contribute less intraocular scattering in the eyes undergoing SMILE.

  13. Effects of tramadol and acepromazine on intraocular pressure and pupil diameter in young healthy cats

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    Deise Cristine Schroder

    2018-03-01

    Full Text Available ABSTRACT: This study aimed to investigate the effects of the systemic administration of acepromazine, tramadol and the association of both on intraocular pressure (IOP and pupil diameter (PD in young healthy cats. Cats were randomly allocated into three groups (n=10/each and intramuscular acepromazine (AG, tramadol (TG or acepromazine combined with tramadol (ATG were injected. PD (electronic caliper and IOP (applanation tonometry were assessed before (baseline and following 15, 30, 60, and 120 minutes of treatments. It was verified that in AG, PD decreased significantly from time point 30 to 120 (P=0.002, but such reduction did not differ significantly from baseline (P=0.89. In TG, PD increased significantly from the first 15 minutes, until the last time point of evaluation (P0.05. It can be concluded that tramadol alone or in association with acepromazine produced significant mydriasis for up to 120 minutes, without changing IOP values in normal cats. Results of this study suggested that tramadol alone or in association with acepromazine caused significant mydriasis and did not change IOP values in normal cats. Therefore, it may be considered a satisfactory pre-anesthetic combination for ophthalmic surgery in cats. However, further studies are warranted on the use of such protocols in cats with ophthalmic diseases undergoing ocular or intraocular surgery.

  14. Ophthalmic artery chemosurgery for less advanced intraocular retinoblastoma: five year review.

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    David H Abramson

    Full Text Available BACKGROUND: Ophthalmic artery chemosurgery (OAC for retinoblastoma was introduced by us 5 years ago for advanced intraocular retinoblastoma. Because the success was higher than with existing alternatives and systemic side effects limited we have now treated less advanced intraocular retinoblastoma (Reese-Ellsworth (RE I-III and International Classification Retinoblastoma (ICRB B and C. METHODOLOGY/PRINCIPAL FINDINGS: Retrospective review of 5 year experience in eyes with Reese Ellsworth (Table 1 I (7 eyes, II (6 eyes or III (6 eyes and/or International Classification (Table 2 B (19 eyes and C (11 eyes treated with OAC (melphalan with or without topotecan introduced directly into the ophthalmic artery. Patient survival was 100%. Ocular event-free survival was 100% for Reese-Ellsworth Groups I, II and III (and 96% for ICRB B and C at a median of 16 months follow-up. One ICRB Group C (Reese-Ellsworth Vb eye could not be treated on the second attempt for technical reasons and was therefore enucleated. No patient required a port and only one patient required transfusion of blood products. The electroretinogram (ERG was unchanged or improved in 14/19 eyes. CONCLUSIONS/SIGNIFICANCE: Ophthalmic artery chemosurgery for retinoblastoma that was Reese-Ellsworth I, II and III (or International Classification B or C was associated with high success (100% of treatable eyes were retained and limited toxicity with results that equal or exceed conventional therapy with less toxicity.

  15. Risk factors for severe neutropenia following intra-arterial chemotherapy for intra-ocular retinoblastoma.

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    Ira J Dunkel

    Full Text Available PURPOSE: Intra-arterial chemotherapy is a promising strategy for intra-ocular retinoblastoma. Neutropenia is the most commonly encountered systemic toxicity and in this study we aimed to determine the risk factors associated with the development of severe (≥ grade 3 neutropenia. METHODS: Retrospective review of 187 evaluable cycles of melphalan-containing intra-arterial chemotherapy from the first three cycles administered to 106 patients with intra-ocular retinoblastoma from May 2006 to June 2011. Cycles were considered to be evaluable if (1 blood count results were available in the 7 to 14 days post-treatment interval and (2 concurrent intravenous chemotherapy was not administered. Toxicity was assessed via the Common Terminology Criteria for Adverse Events version 4.0. RESULTS: 54 cycles (29% were associated with grade 3 (n = 43 or grade 4 (n = 11 neutropenia. Multivariate stepwise logistic regression revealed that a higher melphalan dose (>0.40 mg/kg was significantly associated with severe neutropenia during all 3 cycles (odds ratio during cycle one 4.11, 95% confidence interval 1.33-12.73, p = 0.01, but the addition of topotecan and/or carboplatin were not. Prior treatment with systemic chemotherapy was not associated with severe neutropenia risk in any analysis. CONCLUSIONS: Intra-arterial melphalan-based chemotherapy can cause severe neutropenia, especially when a dose of greater than 0.40 mg/kg is administered. Further study with a larger sample may be warranted.

  16. del alcoholismo

    Directory of Open Access Journals (Sweden)

    Rodrigo Arias Duque

    2005-01-01

    Full Text Available Desde el punto de vista farmacológico, es importante comprender qué es el alcohol y cómo actúa en el organismo. No existe una causa simple, sino una interacción complicada de factores neuroquímicos, fisiológicos, psicológicos y sociales que originan y desarrollan esta grave enfermedad fármaco-dependiente. La acción psicofisiológica y farmacodinámica del alcohol es fundamentalmente depresiva, por la reducción de la transmisión sináptica en el sistema nervioso humano. Es un hecho conocido que el consumo excesivo de alcohol causa una disfunción aguda y crónica del cerebro, produciendo trastornos en el sistema nervioso central, presentando alteraciones en la memoria y en las funciones intelectuales como cálculo, comprensión y aprendizaje. A nivel hepático tiene lugar, en su mayoría, el metabolismo del alcohol, produciéndose un hígado graso alcohólico, aumentando el tamaño, terminando en necrosis e inflamación grave del hígado; esto se llama hepatitis alcohólica, y si se sigue consumiendo alcohol se desarrollará la cirrosis. El alcohol también ha estado relacionado con alteraciones del miocardio; se ha constatado en animales de experimentación sanos que tanto la velocidad de contracción del músculo cardiaco y su máxima tensión disminuyen en presencia del alcohol, como consecuencia, la fuerza de cada contracción y el aumento de presión en el ventrículo izquierdo son menores, perdiendo eficacia el corazón como bomba.

  17. Fratura tipo explosão da coluna torácica e lombar: correlação entre o segmento biomecânico sagital acometido e as alterações estruturais da vértebra fraturada

    OpenAIRE

    Silva,Matheus Luís da; Tisot,Rodrigo Arnold; Vieira,Juliano Silveira Luiz; Santos,Renato Tadeu dos; Tisot,Orley Fauth

    2013-01-01

    OBJETIVO: Analisar as fraturas tipo explosão da coluna torácica e lombar e fazer a correlação entre o segmento biomecânico sagital acometido e as alterações estruturais da vértebra fraturada. MÉTODOS: Estudo retrospectivo de 72 pacientes com fraturas tipo explosão da coluna torácica e lombar. O estreitamento do canal vertebral, o colapso vertebral e a cifose local foram avaliados em três segmentos distintos: torácico, transição toracolombar e lombar. RESULTADOS: Houve diferença estatística si...

  18. Tumour necrosis factor-induced uveitis in the Lewis rat is associated with intraocular interleukin 6 production

    NARCIS (Netherlands)

    de Vos, A. F.; van Haren, M. A.; Verhagen, C.; Hoekzema, R.; Kijlstra, A.

    1995-01-01

    Lewis rats were injected with recombinant murine tumour necrosis factor-alpha either intravitreally (0.08-50 ng) or intracardially (1 microgram). The intraocular inflammatory response induced by tumour necrosis factor was examined by slit-lamp and protein extravasation into aqueous humor was

  19. Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility

    NARCIS (Netherlands)

    Chintalapudi, S.R. (Sumana R.); Maria, D. (Doaa); Di Wang, X. (Xiang); Bailey, J.N.C. (Jessica N. Cooke); Allingham, R. (Rand); M.H. Brilliant (Murray H.); D.L. Budenz (Donald L.); J. Fingert (John); D. Gaasterland (Douglas); T. Gaasterland (Terry); J.L. Haines (Jonathan); Hark, L. (Lisa); M.A. Hauser (Michael); R.P. Igo Jr. (Robert); Hee Kang, J. (Jae); P. Kraft (Peter); R.K. Lee (Richard K.); P.A. Lichter (Paul A.); Liu, Y. (Yutao); Moroi, S. (Syoko); L.R. Pasquale (Louis); M.A. Pericak-Vance (Margaret); A. Realini (Anthony); Rhee, D. (Doug); Richards, J.R. (Julia R.); Ritch, R. (Robert); J.S. Schuman (Joel S.); W.K. Scott (William); K. Singh (Kuldev); A.J. Sit (Arthur J.); D. Vollrath (Douglas); G. Wollstein (Gadi); D.J. Zack (Donald); T. Aung (Tin); Bonnemaijer, P. (Peter); Cheng, C.-Y. (Cheng-Yu); J.E. Craig (Jamie); C.M. van Duijn (Cornelia); P. Gharahkhani (Puya); Iglesias Gonzalez, A. (Adriana); Hammond, C.J. (Christopher J.); Hewitt, A. (Alex); Hoehn, R. (Rene); Jonansson, F. (Fridbert); A.P. Khawaja (Anthony); Chuen Khor, C. (Chiea); C.C.W. Klaver (Caroline); A.J. Lotery (Andrew); D.A. Mackey (David); MacGregor, S. (Stuart); Pang, C. (Calvin); F. Pasutto (Francesca); J-A. Zwart (John-Anker); G. Thorleifsson (Gudmar); Thorsteinsdottir, U. (Unnar); V. Vitart (Veronique); E.N. Vithana (Eranga); T.L. Young (Terri L.); T. Zeller (Tanja); P.G. Hysi (Pirro); J.L. Wiggs (Janey L.); R.W. Williams (Robert W.); Jablonski, M.M. (Monica M.)

    2017-01-01

    textabstractGlaucoma is a multi-factorial blinding disease in which genetic factors play an important role. Elevated intraocular pressure is a highly heritable risk factor for primary open angle glaucoma and currently the only target for glaucoma therapy. Our study helps to better understand

  20. Effect of altered eating habits and periods during Ramadan fasting on intraocular pressure, tear secretion, corneal and anterior chamber parameters

    NARCIS (Netherlands)

    Kerimoglu, H.; Ozturk, B.; Gunduz, K.; Bozkurt, B.; Kamis, U.; Okka, M.

    Purpose To determine whether altered eating habits and periods, especially the pre-dawn meal, during Ramadan fasting have any significant effect on intraocular pressure (IOP), tear secretion, corneal and anterior chamber parameters. Methods IOP, basal tear secretion (BTS), reflex tear secretion