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Sample records for intra operative radiation

  1. Intra-operative radiation treatment of cancers

    International Nuclear Information System (INIS)

    Dubois, J.B.; Joyeux, H.; Solassol, C.; Pujol, H.

    1986-01-01

    Intra-operative radiation treatment (I.O.R.T.) is concerning the treatment either of an unresectable tumor or of tumor bed after complete excision of a primary tumor and its first draining lymph nodes. We describe X-ray and electrons techniques and we discuss the delivered doses according to experimental and clinical data. According to the residual disease (macroscopic or microscopic), to the healthy tissues in the target volume, and the histological type, single doses from 20 Gy to 40 Gy can be delivered. Our preliminary results are reported: 25 patients with resectable tumors of the cardia, the stomach and the pancreas, 5 patients with pelvic recurrences of colon and rectum carcinomas. Therapeutic results of the I.O.R.T. providing from the literature are discussed. The I.O.R.T. indications are defined as palliative (unresectable tumors) and curative (irradiation of tumor bed after complete excision of the tumor) [fr

  2. Intra-operative radiation therapy in cancer of the pancreas

    International Nuclear Information System (INIS)

    Dubois, J.B.; Gu, S.D.; Saint-Aubert, B.; Joyeux, H.; Solassol, C.; Pujol, H.

    1991-01-01

    We report our experience concerning 22 pancreatic carcinoma bearing patients treated with intra-operative radiation therapy (IORT) after complete surgical excision: duodenopancreatectomy: 15 patients; isthmic and caudal pancreatectomy: 2 patients; total pancreatectomy: 5 patients. The dose delivered to the tumor bed was 20 Gy in 12 patients, 18 Gy in 3 patients and 15 Gy in 7 patients. Three patients died within the 1st month post-surgery from intercurrent diseases. Post-operative morbidity was not significantly modified by IORT as compared to purely surgical treated patients. Out of 19 evaluable patients, we observed local control in 16 patients (79.4%). Causes of death (15/19 patients) were: distant metastases with local control: 7 patients; in situ local failure: 3 patients; regional recurrence outside of the IORT fields: 2 patients; intercurrent diseases: 3 patients. Four patients are still alive without evolutive disease. The median overall survival is 6 months. The mean overall survival is 10.56 months. Excluding patients who died from complications and intercurrent diseases, the median survival is 10 mths and the mean survival 14.5 mths. These results emphasize the improvement in local control with IORT, but without significant improvement in survival which is dependent on local evolution and also systemic disease [fr

  3. Intra-operative radiation therapy with laser-accelerated carbon ions

    Science.gov (United States)

    Mur, P.; Bellido, P.; Seimetz, M.; Lera, R.; Ruiz-de la Cruz, A.; Galán, M.; Roso, L.; Sánchez, F.; Benlloch, J. M.

    2017-03-01

    Laser accelerators have long been proposed as beam source for hadron therapy. However, the high energies necessary for the treatment of deep-lying tumours, combined with stringent requirements on the beam quality, are still a severe challenge. In the present work, we discuss the applicability of laser-accelerated carbon ions at moderate energies (100-480 MeV) to the irradiation of superficial lesions. We propose a new therapeutic modality which combines the versatility of Intra-Operative Radiation Therapy with the advantages of carbon ions as compared to photon and electron radiation. To justify this idea a feasibility study has been carried out, focused on the uniformity of dose deposition inside the treatment volume. Physical and biological aspects characteristic to laser-accelerated carbon ion beams are considered. A GATE simulation has been performed, showing an approximately uniform depth-dose profile up to a maximum penetration depth of 5 mm for a single radiation boost of 10 GyE.

  4. High-dose rate intra-operative radiation therapy for pediatric solid tumors

    International Nuclear Information System (INIS)

    Merchant, T.E.; Zelefsky, M.J.; Sheldon, J.M.; LaQuaglia, M.B.; Harrison, L.B.

    1996-01-01

    Fifteen pediatric patients with solid tumors received treatment on a phase I protocol designed to test the feasibility and safety of high-dose rate intra-operative radiation therapy (IORT) via a remote afterloader. Patients with Ewing's sarcoma (n=5), rhabdomyosarcoma (n=3), soft-tissue sarcoma (n=3), Wilm's tumor (n=2), osteosarcoma, and immature teratoma were included. IORT was used in the initial management of nine patients and at the time of recurrence in six. Indications for treatment included gross residual disease in four and suspected microscopic disease in eleven. The general sites treated were the abdomen (n=3), chest-wall (n=7), and pelvis (n=5). All patients were pre-treated with chemotherapy, four received prior external beam radiation therapy at the IORT site, and eight underwent an attempt at resection prior to the procedure during which IORT was performed. A minimum dose of 1200 cGy was prescribed to a depth of 0.5 cm from a multi-channel tissue-equivalent applicator. Complications ascribed to IORT included an abscess, delayed wound healing, cytopenia, and fluid loculations. Five patients received supplemental external beam radiation therapy to the IORT site without complication. At the time of IORT, three patients were known to have locally disseminated disease within the pleural cavity and one had pulmonary metastases. With a median follow-up of 18 months, the actuarial rate of local control, metastases-free and overall survival were 60%, 75%, and 50%. The patterns of failure were local (n=1), distant (n=1), and local + distant (n=1). Four patients are alive with active disease, six are alive with no evidence of disease, and the remaining five are dead from disease (n=2), other causes (n=1), or treatment (n=2). Although local failure remains a common problem in the treatment of pediatric solid tumors, the potential to improve local control with high doses of radiation must be balanced against the risk of late effects. The ability to confine the

  5. High-dose rate intra-operative radiation therapy for local advanced and recurrent colorectal cancer

    International Nuclear Information System (INIS)

    Harrison, L.B.; Mychalczak, B.; Enker, W.; Anderson, L.; Cohen, A.E.; Minsky, B.

    1996-01-01

    In an effort to improve the local control for advanced and recurrent cancers of the rectum, we have integrated high-dose rate intra-operative radiation therapy (HDR-IORT) into the treatment program. Between 11/92 and 10/95, 47 patients (pts) were treated. There were 26 males and 21 females whose ages ranged from 30-80 (median = 62) years. There were 19 pts with primary unresectable rectal cancer, and 28 pts who were treated for recurrent rectal cancer. Histology was adenocarcinoma - 45 pts, squamous cancer - 2 pts. The range of follow-up is 1-34 months (median = 14 months). The majority of primary unresectable pts received pre-operative radiation therapy (4500-5040 cGy) with chemotherapy (5-FU with Leucovorin) 4-6 weeks later, they underwent resection + HDR-IORT (1200 cGy). For the 28 pts with recurrent cancer, the majority received surgery and HDR-IORT alone because they had received prior RT. For the pts with primary unresectable disease, actuarial 2-year local control was 77%, actuarial distant metastasis-free survival was 71%, disease free survival was 66%, and overall survival was 84%. For those pts with recurrent disease, actuarial 2-year local control rate was 65%, distant metastasis-free survival was 65%, disease free survival was 47%, and overall survival was 61%. Complications occurred in 36%. There were no cases where the anatomical distribution of disease, or technical limitations prevented the adequate delivery of HDR-IORT. We conclude that this technique was most versatile, and enabled all appropriate pts to receive IORT. The preliminary data in terms of local control are encouraging, even for the poor prognostic sub-group of pts with recurrent cancer

  6. Radiation protection for an intra-operative X-ray device.

    Science.gov (United States)

    Eaton, D J; Gonzalez, R; Duck, S; Keshtgar, M

    2011-11-01

    Therapeutic partial breast irradiation can be delivered intra-operatively using the Intrabeam 50 kVp compact X-ray device. Spherical applicators are added to the source to give an isotropic radiation dose. The low energy of this unit leads to rapid attenuation with distance, but dose rates are much greater than for diagnostic procedures. To investigate the shielding requirements for this unit, attenuation measurements were carried out with manufacturer-provided tungsten-rubber sheets, lead, plasterboard and bricks. A prospective environmental dose rate survey was also conducted in the designated theatre. As a result of isotropic geometry, the scattered dose around shielding can be 1% of primary and thus often dominates measured dose rates compared with transmission. The absorbed dose rate of the unshielded source at 1 m was 11.6 mGy h(-1) but this was reduced by 95% with the shielding sheets. Measured values for the common shielding materials were similar to reference data for the attenuation of a 50 kVp diagnostic X-ray beam. Two lead screens were constructed to shield operators remaining in the theatre and an air vent into a service corridor. A lead apron would also provide suitable attenuation, although a screen allows greater flexibility for treatment operators. With these measures, staff doses were reduced to negligible quantities. Survey measurements taken during patient treatments confirmed no additional measures were required, but the theatre should be a controlled area and access restricted. Results from this study and reference data can be used for planning other facilities.

  7. Intra-operative radiation therapy for malignant brain tumours: rationale, method, and treatment results of cerebral glioblastomas

    International Nuclear Information System (INIS)

    Matsutani, M.; Nakamura, O.; Nagashima, T.

    1994-01-01

    In radiation therapy for malignant brain tumours, the dose of radiation that can be safely delivered to a tumour is limited by the radiation tolerance of the adjacent normal brain tissue. Among various radiation modalities to produce local tumour eradication without unacceptable complications, we chose a large, single irradiation dose during the operation (intra-operative radiation therapy, IORT). In contrast to X-ray or Cobalt-60 gamma ray irradiation, IORT with a high-energy electron beam delivered by the Shimadzu 20 MeV betatron provides acceptable dose homogeneity with rapid fall-off of the radiation dose beyond the treatment volume. Thus, IORT has the advantage of precise demarcation of the target volume, minimum damage to surrounding normal tissues, and a high absorbed target dose (15-25 Gy in 5-10 min). On the basis of our experience with 170 patients treated by IORT, we established the treatment indications and method in patients with malignant brain tumours. IORT with a dose of 15-25 Gy was delivered to widely resected tumours followed by external radiation therapy. No acute or subacute complications were observed. Treatment results of 30 patients with glioblastoma treated by IORT (mean 18.3 Gy) combined with external radiation therapy (mean 58.5 Gy) resulted in a median survival of 119 weeks and a 2-year survival rate of 61 %. (authors)

  8. Simulated versus realistic intra operative radiation therapy (I.O.R.T.) treatment in operating room: from knowledge of stray radiation to action

    International Nuclear Information System (INIS)

    Andreoli, S.; Moretti, R.; Catalano, M.; Locatelli, F.

    2006-01-01

    Intra-Operative Radiation Therapy (I.O.R.T.) is carried out with electron beams produced by a Linac (Linear Accelerator) generally used for conventional radiotherapy with external beam, or by dedicated accelerators that can be employed directly into an operating room. I.O.R.T. refers to the application of radiation during a surgical intervention, after the removal of a neoplastic mass. I.O.R.T. uses on the tumour area a direct irradiation, for the possible localisation of sub-clinic illness or macroscopic residue in the case of non-radical resection. Intra-Operative Radiotherapy foresees a single session only, generally preceded or followed by radiotherapy with external beam. It allows the achievement of a selective radiation boost on the tumour volume. In some cases, it can also be used as a one-time/stand alone treatment in initial cancer of small volume, or in unresectable malignancies for palliative purpose. The technical advantages of I.O.R.T. consist in the direct visual control of the target volume, and in the possibility to protect the healthy tissues by moving them away from the path of the radiation beam. The use of electron beams allows the administration of a homogeneous dose to a selected layer of tissues surrounding the tumour. The following professional staff forms the Operative Group: radiation oncologist, surgeon, anaesthetist, medical physicist, radiation technologist, nurse.The choice of a simulation geometry very similar to the clinical situation allows to evaluate radioprotection data very close to the real situation. For a fixed layout, an anthropomorphic phantom was positioned on the operating bed and a breast I.O.R.T. treatment was simulated positioning all the accessories of the operating room in their typical positions. A detailed dose mapping was performed with a Victoreen 450P ionisation chamber and with environment film-dosimeter on the walls of the operating room during the simulation of the clinical treatment. The simulation appears

  9. Feasibility of integrating a multi-camera optical tracking system in intra-operative electron radiation therapy scenarios

    International Nuclear Information System (INIS)

    García-Vázquez, V; Marinetto, E; Santos-Miranda, J A; Calvo, F A; Desco, M; Pascau, J

    2013-01-01

    Intra-operative electron radiation therapy (IOERT) combines surgery and ionizing radiation applied directly to an exposed unresected tumour mass or to a post-resection tumour bed. The radiation is collimated and conducted by a specific applicator docked to the linear accelerator. The dose distribution in tissues to be irradiated and in organs at risk can be planned through a pre-operative computed tomography (CT) study. However, surgical retraction of structures and resection of a tumour affecting normal tissues significantly modify the patient's geometry. Therefore, the treatment parameters (applicator dimension, pose (position and orientation), bevel angle, and beam energy) may require the original IOERT treatment plan to be modified depending on the actual surgical scenario. We propose the use of a multi-camera optical tracking system to reliably record the actual pose of the IOERT applicator in relation to the patient's anatomy in an environment prone to occlusion problems. This information can be integrated in the radio-surgical treatment planning system in order to generate a real-time accurate description of the IOERT scenario. We assessed the accuracy of the applicator pose by performing a phantom-based study that resembled three real clinical IOERT scenarios. The error obtained (2 mm) was below the acceptance threshold for external radiotherapy practice, thus encouraging future implementation of this approach in real clinical IOERT scenarios. (paper)

  10. Intra-operative radiation therapy in cancer of the pancreas. La radiotherapie peroperatoire dans les cancers du pancreas

    Energy Technology Data Exchange (ETDEWEB)

    Dubois, J.B.; Gu, S.D.; Saint-Aubert, B.; Joyeux, H.; Solassol, C.; Pujol, H. (Centre Regional de Lutte contre le Cancer, 34 - Montpellier (FR))

    1991-03-01

    We report our experience concerning 22 pancreatic carcinoma bearing patients treated with intra-operative radiation therapy (IORT) after complete surgical excision: duodenopancreatectomy: 15 patients; isthmic and caudal pancreatectomy: 2 patients; total pancreatectomy: 5 patients. The dose delivered to the tumor bed was 20 Gy in 12 patients, 18 Gy in 3 patients and 15 Gy in 7 patients. Three patients died within the 1st month post-surgery from intercurrent diseases. Post-operative morbidity was not significantly modified by IORT as compared to purely surgical treated patients. Out of 19 evaluable patients, we observed local control in 16 patients (79.4%). Causes of death (15/19 patients) were: distant metastases with local control: 7 patients; in situ local failure: 3 patients; regional recurrence outside of the IORT fields: 2 patients; intercurrent diseases: 3 patients. Four patients are still alive without evolutive disease. The median overall survival is 6 months. The mean overall survival is 10.56 months. Excluding patients who died from complications and intercurrent diseases, the median survival is 10 mths and the mean survival 14.5 mths. These results emphasize the improvement in local control with IORT, but without significant improvement in survival which is dependent on local evolution and also systemic disease.

  11. Characterization of a microDiamond detector in high-dose-per-pulse electron beams for intra operative radiation therapy.

    Science.gov (United States)

    Di Venanzio, C; Marinelli, Marco; Tonnetti, A; Verona-Rinati, G; Falco, M D; Pimpinella, M; Ciccotelli, A; De Stefano, S; Felici, G; Marangoni, F

    2015-12-01

    To characterize a synthetic diamond dosimeter (PTW Freiburg microDiamond 60019) in high dose-per-pulse electron beams produced by an Intra Operative Radiation Therapy (IORT) dedicated accelerator. The dosimetric properties of the microDiamond were assessed under 6, 8 and 9 MeV electron beams by a NOVAC11 mobile accelerator (Sordina IORT Technologies S.p.A.). The characterization was carried out with dose-per-pulse ranging from 26 to 105 mGy per pulse. The microDiamond performance was compared with an Advanced Markus ionization chamber and a PTW silicon diode E in terms of dose linearity, percentage depth dose (PDD) curves, beam profiles and output factors. A good linearity of the microDiamond response was verified in the dose range from 0.2 Gy to 28 Gy. A sensitivity of 1.29 nC/Gy was measured under IORT electron beams, resulting within 1% with respect to the one obtained in reference condition under (60)Co gamma irradiation. PDD measurements were found in agreement with the ones by the reference dosimeters, with differences in R50 values below 0.3 mm. Profile measurements evidenced a high spatial resolution of the microDiamond, slightly worse than the one of the silicon diode. The penumbra widths measured by the microDiamond resulted approximately 0.5 mm larger than the ones by the Silicon diode. Output factors measured by the microDiamond were found within 2% with those obtained by the Advanced Markus down to 3 cm diameter field sizes. The microDiamond dosimeter was demonstrated to be suitable for precise dosimetry in IORT applications under high dose-per-pulse conditions. Copyright © 2015 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  12. Analysis of radiation risk to patients from intra-operative use of the mobile X-ray system (C-arm

    Directory of Open Access Journals (Sweden)

    Yang-Sub Lee

    2015-01-01

    Full Text Available Background: The aim of this study was to investigate clinical applications of mobile C-arms and consequent radiation risk, to increase medical attention on radiation protection, and to provide basic data for safe radiation use in the operating room. Materials and Methods: In this study, a total of 374 surgical operations, conducted using a portable fluoroscopic X-ray system from January to March of 2013, were analyzed. Dose summaries produced by the General Electric C-arm and data elements in digital imaging and communications in the medicine header of Ziehm C-arm, fluoroscopy time were used to obtain dose-area product (DAP and effective dose. Corresponding mean and maximum values were calculated, and the resulting data on the frequency of application, fluoroscopy time, DAP, and effective dose were compared and analyzed in terms of surgical specialty and operation types. Results: Orthopedic surgery was the most frequent with 165 cases (44.1%. The highest DAP value and effective dose were found in liver transplant among surgical specialty fields, with mean values of 2.90 ± 3.76 mGy∙m 2 and 58 ± 75.2 mSv, respectively (P = 0.0001. The highest DAP value and effective dose were observed in intra-operative mesenteric portography among types of surgery, showing mean values of 2.90 ± 3.81 mGy∙m 2 and 58.03 ± 76.24 mSv, respectively (P = 0.0001. Conclusion: Because DAP varies significantly across surgical specialties and types of operation, aggressive efforts to understand the effects of radiation dose is critical for radiation protection from intra-operative use of mobile C-arms.

  13. Intra-operative complications in sagittal and vertical ramus osteotomies

    NARCIS (Netherlands)

    van Merkesteyn, J. P.; Groot, R. H.; van Leeuwaarden, R.; Kroon, F. H.

    1987-01-01

    In orthognatic surgery of the mandibular ramus, intra-operative complications as a lesion of the inferior alveolar nerve, fractures of the osteotomised segments, incomplete sectioning, malpositioning of segments and haemorrhage may occur. In this report, intra-operative complications in 124 sagittal

  14. Perception of Nigerian anaesthetists on intra-operative death ...

    African Journals Online (AJOL)

    Perception of Nigerian anaesthetists on intra-operative death. SOA Olateju, AT Adenekan, BB Osinaike, OM Fatungase, ON Akanmu, AA Adebayo. Abstract. Background: Intra-operative death is an unusual devastating occurrence in anaesthetic practice, and it is of serious concern when it happens. Objectives: To assess the ...

  15. Capturing intra-operative safety information using surgical wikis.

    Science.gov (United States)

    Edwards, Michael; Agha, Riaz; Coughlan, Jane

    2013-03-01

    Expert surgeons use a mass of intra-operative information, as well as pre- and post-operative information to complete operations safely. Trainees acquired this intra-operative knowledge at the operating table, now largely diminished by the working time directive. Wikis offer unexplored approaches to capturing and disseminating expert knowledge to further promote safer surgery for the trainee. Grafting an abdominal aortic aneurysm represents a potentially high-risk operation demanding extreme safety measures. Operative details, presented on a surgical wiki in the form of a script and content analysed to classify types of safety information. The intra-operative part of the script contained 2,743 items of essential surgical information, comprising 21 sections, 405 steps and 2,317 items of back-up information; 155 (5.7%) of them were also specific intra-operative safety checks. Best case scenarios consisted of 1,077 items of intra-operative information, 69 of which were safety checks. Worse case and rare scenarios required a further 1,666 items of information, including 86 safety checks. Wikis are relevant to surgical practice specifically as a platform for knowledge sharing and optimising the available operating time of trainees, as a very large amount of minutely detailed information essential for a safe major operation can be captured.

  16. Intra-arterial and intra-venous chemotherapy combined with radiation in the treatment of brain tumours

    International Nuclear Information System (INIS)

    Watne, K.

    1992-01-01

    The present investigations were undertaken to study the effect of combining different modalities of chemotherapy with radiation in post-operative treatment of brain tumours. The conclusions and clinical implication of the investigations are as follows: The combination of combined intra-arterial chemotherapy followed by radiation leads to an increased median survival with more long term survivors in patients with anaplastic astrocytomas and in patients older than 40 years with astrocytomas. In patients with glioblastoma multiforme, this modality of treatment do not improve median survival, but an increased number of long-term survivors may be seen. Patients younger than 40 years with astrocytomas do not benefit from this modality of treatment. A parallelism exists between sensitivity to chemotherapy and response to radiotherapy. Patients who will benefit from the treatment may be selected early, normally two months after treatment start. Combining intra-arterial chemotherapy and radiation does not lead to an increased incidence of adverse CNS reactions. Specific transient abnormalities in the brain may occur during the first year after treatment and may be misinterpreted as tumour recurrence. EEG may be valuable in predicting adverse CNS reactions following treatment. Nuclear brain scan may be of valuable in selecting the patients who are in danger of developing adverse CNS reactions. Intra-arterial chemotherapy does have an effect in patients with brain tumours who have recurrent tumour after radiation. The most important prognostic factors are age, corticosteroid dependency at treatment start, performance status, histology and frontal lobe location. 103 refs., 2 tabs

  17. Intra-operative cholangiography for the diagnosis of choledocholithiasis

    International Nuclear Information System (INIS)

    Raab, M.; Schroeder, A.

    1987-01-01

    521 patients with benign disorders of the extrahepatic bile duct system were examined retrospectively. Bile duct stones suspected by pre-operative intravenous cholangiography could be verified by surgery in but 41,6% of the cases. Routine intra-operative cholangiography was not performed in those cases with pre-operative indication of choledocus revision and with rare failure of cystic duct cannulation. Evaluation of 448 intra-operative cholangiographies revealed the diagnosis of choledocholithiasis to be false positive in 3,3% and false negative in 1,1%. Intra-operative X-ray examination allowed to diagnose 45 cases of choledocholithiasis subsequently verified by surgery. Most of these patients exhibited clinical signs (transient jaundice, changes in blood chemistry). Follow-up identified two patients whose bile duct stones had been overlooked. (orig.) [de

  18. Intra-operative cholangiography for the diagnosis of choledocholithiasis

    Energy Technology Data Exchange (ETDEWEB)

    Raab, M.; Schroeder, A.

    1987-01-01

    521 patients with benign disorders of the extrahepatic bile duct system were examined retrospectively. Bile duct stones suspected by pre-operative intravenous cholangiography could be verified by surgery in but 41,6% of the cases. Routine intra-operative cholangiography was not performed in those cases with pre-operative indication of choledocus revision and with rare failure of cystic duct cannulation. Evaluation of 448 intra-operative cholangiographies revealed the diagnosis of choledocholithiasis to be false positive in 3,3% and false negative in 1,1%. Intra-operative X-ray examination allowed to diagnose 45 cases of choledocholithiasis subsequently verified by surgery. Most of these patients exhibited clinical signs (transient jaundice, changes in blood chemistry). Follow-up identified two patients whose bile duct stones had been overlooked.

  19. Attenuation measurements show that the presence of a TachoSil surgical patch will not compromise target irradiation in intra-operative electron radiation therapy or high-dose-rate brachytherapy.

    Science.gov (United States)

    Sarmento, Sandra; Costa, Filipa; Pereira, Alexandre; Lencart, Joana; Dias, Anabela; Cunha, Luís; Sousa, Olga; Silva, José Pedro; Santos, Lúcio

    2015-01-09

    Surgery of locally advanced and/or recurrent rectal cancer can be complemented with intra-operative electron radiation therapy (IOERT) to deliver a single dose of radiation directly to the unresectable margins, while sparing nearby sensitive organs/structures. Haemorrhages may occur and can affect the dose distribution, leading to an incorrect target irradiation. The TachoSil (TS) surgical patch, when activated, creates a fibrin clot at the surgical site to achieve haemostasis. The aim of this work was to determine the effect of TS on the dose distribution, and ascertain whether it could be used in combination with IOERT. This characterization was extended to include high dose rate (HDR) intraoperative brachytherapy, which is sometimes used at other institutions instead of IOERT. CT images of the TS patch were acquired for initial characterization. Dosimetric measurements were performed in a water tank phantom, using a conventional LINAC with a hard-docking system of cylindrical applicators. Percentage Depth Dose (PDD) curves were obtained, and measurements made at the depth of dose maximum for the three clinically used electron energies (6, 9 and 12MeV), first without any attenuator and then with the activated patch of TS completely covering the tip of the IOERT applicator. For HDR brachytherapy, a measurement setup was improvised using a solid water phantom and a Farmer ionization chamber. Our measurements show that the attenuation of a TachoSil patch is negligible, both for high energy electron beams (6 to 12MeV), and for a HDR (192)Ir brachytherapy source. Our results cannot be extrapolated to lower beam energies such as 50 kVp X-rays, which are sometimes used for breast IORT. The TachoSil surgical patch can be used in IORT procedures using 6MeV electron energies or higher, or HDR (192)Ir brachytherapy.

  20. Appropriateness of Intra-Operative Blood Transfusion In Children at ...

    African Journals Online (AJOL)

    Background: The decision to transfuse intra-operatively is based on preoperative haemoglobin (Hb), estimated blood loss and physiological variables. The visual estimate of blood loss is notoriously unreliable especially with small volumes of blood losses in children. Objectives :We sought therefore to determine the ...

  1. Unexpected intra-operative diagnosis of a large cystic ...

    African Journals Online (AJOL)

    draining directly into the inferior vena cava. The patient became. Unexpected intra-operative diagnosis of a large cystic phaeochromocytoma and secondary nifedipine pharmacobezoar. D N Ginther, MD, BSc. Division of General Surgery, Royal University Hospital, Saskatoon, SK, Canada. S Kriegler, MD, MB ChB, MMed, ...

  2. Comparative Study Of Intra-Operative Pelvimetry With Calipers And ...

    African Journals Online (AJOL)

    The pelvic measurement of patients who have had a caesarean section was done using Pelvic Calipers (intra-operative) and x-ray methods. In the former method, during Caesarean sections and after closure of the lower uterine segment incision, a pair of pelvic calipers was used to measure the true conjugate of the pelvis.

  3. perception of nigerian anaesthetists on intra-operative death

    African Journals Online (AJOL)

    2012-10-01

    Oct 1, 2012 ... East African Medical Journal Vol. 89 No. 10 October 2012. PERCEPTION OF NIGERIAN ANAESTHETISTS ON INTRA-OPERATIVE DEATH. S. O. A. Olateju, MBChB, DA, MPH, FMCA, FICS, Consultant Anaesthetist/Lecturer, A. T. Adenekan, MBBS, DA,. FWACS, Consultant Anaesthetist/Lecturer, ...

  4. Intra-operative parathyroid hormone measurements – experience of ...

    African Journals Online (AJOL)

    Background. Surgery is the treatment of choice for symptomatic primary hyperparathyroidism. The majority of research concerning intra-operative parathyroid hormone (ioPTH) measurements is conducted in university hospitals. Whether ioPTH measurements are feasible and useful in predicting the presence of remaining ...

  5. Pediatric awake craniotomy and intra-operative stimulation mapping.

    Science.gov (United States)

    Balogun, James A; Khan, Osaama H; Taylor, Michael; Dirks, Peter; Der, Tara; Carter Snead Iii, O; Weiss, Shelly; Ochi, Ayako; Drake, James; Rutka, James T

    2014-11-01

    The indications for operating on lesions in or near areas of cortical eloquence balance the benefit of resection with the risk of permanent neurological deficit. In adults, awake craniotomy has become a versatile tool in tumor, epilepsy and functional neurosurgery, permitting intra-operative stimulation mapping particularly for language, sensory and motor cortical pathways. This allows for maximal tumor resection with considerable reduction in the risk of post-operative speech and motor deficits. We report our experience of awake craniotomy and cortical stimulation for epilepsy and supratentorial tumors located in and around eloquent areas in a pediatric population (n=10, five females). The presenting symptom was mainly seizures and all children had normal neurological examinations. Neuroimaging showed lesions in the left opercular (n=4) and precentral or peri-sylvian regions (n=6). Three right-sided and seven left-sided awake craniotomies were performed. Two patients had a history of prior craniotomy. All patients had intra-operative mapping for either speech or motor or both using cortical stimulation. The surgical goal for tumor patients was gross total resection, while for all epilepsy procedures, focal cortical resections were completed without any difficulty. None of the patients had permanent post-operative neurologic deficits. The patient with an epileptic focus over the speech area in the left frontal lobe had a mild word finding difficulty post-operatively but this improved progressively. Follow-up ranged from 6 to 27 months. Pediatric awake craniotomy with intra-operative mapping is a precise, safe and reliable method allowing for resection of lesions in eloquent areas. Further validations on larger number of patients will be needed to verify the utility of this technique in the pediatric population. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. Tissue-engineered heart valves: intra-operative protocol.

    Science.gov (United States)

    Gallo, Michele; Bianco, Roberto; Bottio, Tomaso; Naso, Filippo; Franci, Paolo; Zanella, Fabio; Perona, Giovanni; Busetto, Roberto; Spina, Michele; Gandaglia, Alessandro; Gerosa, Gino

    2013-08-01

    Tissue engineering of heart valves investigates the possibility to create a fully compatible and biomimetic graft able to provide host cell repopulation like the native living valve. Decellularized aortic and pulmonary valves and synthetic polymers have been used to promote the creation of a native-like scaffold suitable to be colonized by cells either in vitro, in dynamic bioreactors or in vivo using different animal models. The herein presented research provides the intra-operative protocol and details of surgical technique. Porcine aortic valve conduits were decellularized and implanted in the right ventricular outflow tract of Vietnamese pigs.

  7. Presentation of the GIE INTRA Group's operational means

    International Nuclear Information System (INIS)

    Cochard, A.

    2010-01-01

    Located on the Chinon nuclear power plant site, the Intra Group is an economic interest grouping which has been created by the three French nuclear operators (EDF, CEA, and COGEMA now AREVA) after the Chernobyl accident. Its missions are to possess permanently available means of intervention in case of severe accident or radiological situation, to be able to intervene at any time on the French territory, to develop a European network of expertise, and to build up an ability centre for robotic intervention in hostile environment. This document briefly presents its different available means: remotely controlled equipment (inside and outside equipment, public works equipment), and radiological characterization equipment. Other aspects are briefly evoked: organization, information transmission, exercises and interventions, international relationships, future trends

  8. Intra-operative removal of chest tube in video-assisted thoracoscopic procedures

    Directory of Open Access Journals (Sweden)

    Moustafa M. El-Badry

    2017-12-01

    Conclusions: Intra-operative removal of chest tube during VATS procedures was a safe technique in well selected patients with an intra-operative successful air-leak test with radiological and clinical follow-up. This technique provided lesser post-operative pain with shorter hospital stay.

  9. Intra-operative blood transfusion among adult surgical patients in a ...

    African Journals Online (AJOL)

    This retrospective study was designed to audit the pattern of intra-operative whole blood transfusion among adult surgical patients over a two-year period. Data were collected on the rate of intra-operative transfusion, estimated blood loss, units of donor blood transfused, pattern of use of autologous blood and circumstances ...

  10. Intra-operative application of optical coherence tomography with an operating microscope.

    Science.gov (United States)

    Just, T; Lankenau, E; Hüttmann, G; Pau, H W

    2009-09-01

    To introduce the use of optical coherence tomography with an operating microscope for intra-operative evaluation of the human larynx. A specially equipped operating microscope with integrated spectral domain optical coherence tomography apparatus was used during microlaryngoscopy. Technical improvements in optical coherence tomography equipment (e.g. pilot beam, variable focal distance, improved image quality and integration into an operating microscope) have enabled greater sensitivity and imaging speed and a non-contact approach. Spectral domain optical coherence tomography now enables a better correlation between optical coherence tomography images and histological findings. With this new technology, the precision of biopsy can be improved during microlaryngoscopy. Use of this new optical coherence tomography technology, integrated into an operating microscope, enables the surgeon to define the biopsy site location and resection plane precisely, while the optical zoom of the operating microscope can be used over the complete range.

  11. Effective dose equivalent to the operator in intra-oral dental radiography

    Energy Technology Data Exchange (ETDEWEB)

    de Haan, R.A.; van Aken, J. (Utrecht Univ., (The Netherlands))

    1990-08-01

    The effective dose equivalent to the operator in intra-oral dental radiography has been determined. The exposure from a bitewing radiograph and periapical views of the left maxillary incisors and first molar was measured at nine heights and 16 positions, all 1 m from the patient. The effective dose equivalent was determined using data from ICRP 51 (International Commission on Radiological Protection: Data for Use in Protection Against External Radiation). The values presented are related to an exposure of 1 C kg-1 (3876 R) measured free in air at the tube-end. They thus constitute ratios which are not influenced by the sensitivity of the film or other detector used and form standard tables which permit the calculation of the effective dose equivalent in clinical situations.

  12. Effective dose equivalent to the operator in intra-oral dental radiography

    International Nuclear Information System (INIS)

    de Haan, R.A.; van Aken, J.

    1990-01-01

    The effective dose equivalent to the operator in intra-oral dental radiography has been determined. The exposure from a bitewing radiograph and periapical views of the left maxillary incisors and first molar was measured at nine heights and 16 positions, all 1 m from the patient. The effective dose equivalent was determined using data from ICRP 51 (International Commission on Radiological Protection: Data for Use in Protection Against External Radiation). The values presented are related to an exposure of 1 C kg-1 (3876 R) measured free in air at the tube-end. They thus constitute ratios which are not influenced by the sensitivity of the film or other detector used and form standard tables which permit the calculation of the effective dose equivalent in clinical situations

  13. Laboratory operation during radiation emergency

    International Nuclear Information System (INIS)

    Bunata, M.; Tecl, J.; Prouza, Z.

    2008-01-01

    During radiation emergency, a special operation mode of laboratories of the Radiation Monitoring Network (hereinafter RMN) is expected. The principal factors differing the emergency mode from the normal one are the following: - significantly higher amount of analyzed samples; - high activities of the majority of the samples; - higher risk of personal and equipment contamination; - higher working and psychological demands on laboratory staff. The assuring of the radiation protection requirements of laboratory staff has to be the primary objective, nevertheless the risk of equipment contamination and of samples cross- contamination of course have to be as well taken into consideration. The presentation describes the experience of the RMN Central Laboratory of the National Radiation Protection Institute in Prague (SURO) which was obtained during realization of field tests, in which a radioactive matter was released. These tests allow us to evaluate the source term or radioactivity dispersal balance based on various detection methods with the aim to estimate exposure of the afflicted persons. Tests provided to simulate emergency working conditions in Central Laboratory -high number of contaminated samples, which have to be analyzed in a short time (short half-time of used radionuclide 99m Tc) using sophisticated laboratory techniques (gamma spectrometers, aerosols collectors, etc.). The testing shows the availability of the SURO laboratory to work during the radiation emergency and to participate on its determination. The suitable settings and the ideal number of staff have been found. The average analysis time was approximately 1 minute per sample and the sample results were available just a few minutes after the counting. Moreover, the settings avoided any danger and kept both the crew and the samples safe and secure from contamination. (authors)

  14. Laboratory operation during radiation emergency

    International Nuclear Information System (INIS)

    Bunata, M.; Prouza, Z.; Tecl, J.

    2009-01-01

    During radiation emergency, a special operation mode of laboratories of the Radiation Monitoring Network (hereinafter RMN) is expected. The principal factors differing the emergency mode from the normal one are the following: - significantly higher amount of analyzed samples; - high activities of the majority of the samples; - higher risk of personal and equipment contamination; - higher working and psychological demands on laboratory staff. The assuring of the radiation protection requirements of laboratory staff has to be the primary objective, nevertheless the risk of equipment contamination and of samples cross- contamination of course have to be as well taken into consideration. The presentation describes the experience of the RMN Central Laboratory of the National Radiation Protection Institute in Prague (SURO) which was obtained during realization of field tests, in which a radioactive matter was released. These tests allow us to evaluate the source term or radioactivity dispersal balance based on various detection methods with the aim to estimate exposure of the afflicted persons. Tests provided to simulate emergency working conditions in Central Laboratory - high number of contaminated samples, which have to be analyzed in a short time (short half-time of used radionuclide 99m Tc) using sophisticated laboratory techniques (gamma spectrometers, aerosols collectors, etc.). The testing shows the availability of the SURO laboratory to work during the radiation emergency and to participate on its determination. The suitable settings and the ideal number of staff have been found. The average analysis time was approximately 1 minute per sample and the sample results were available just a few minutes after the counting. Moreover, the settings avoided any danger and kept both the crew and the samples safe and secure from contamination. (authors)

  15. Operational radiation protection: A guide to optimization

    International Nuclear Information System (INIS)

    1990-01-01

    The purpose of this publication is to provide practical guidance on the application of the dose limitation system contained in the Basic Safety Standards for Radiation Protection to operational situations both in large nuclear installations and in much smaller facilities. It is anticipated that this Guide will be useful to both the management and radiation protection staff of operations in which there is a potential for occupational radiation exposures and to the competent authorities with responsibilities for providing a programme of regulatory control. Contents: Dose limitation system; Optimization and its practical application to operational radiation protection; Major elements of an effective operational radiation protection programme; Review of selected parts of the basic safety standards with special reference to operational radiation protection; Optimization of radiation protection; Techniques for the systematic appraisal of operational radiation protection programmes. Refs and figs

  16. The ultrastructure of tumor cells in patients with rectal cancer after pre-operative irradiation and intra-operative cryotherapy

    International Nuclear Information System (INIS)

    Vyinnik, Yu.O.; Kotenko, O.Je.; Nevzorov, V.P.; Chyibyisov, L.P.

    2000-01-01

    Electronic microscopy of the tumor cells was performed to confirm the efficacy of combined pre-operative gamma-therapy and intraoperative cryotherapy (CT). Pre-operative irradiation at the dose of 20 Gy accompanied by intra-operative cryotherapy caused the changes in the ultrastructure, the depth and degree of which allow to consider them destructive and irreversible

  17. Scintigraphic techniques in primary hyperparathyroidism: from pre-operative localisation to intra-operative imaging

    Energy Technology Data Exchange (ETDEWEB)

    Rubello, Domenico [S. Maria della Misericordia Hospital, Service of Nuclear Medicine, Rovigo (Italy); Gross, Milton D. [Department of Veterans Affairs Health System, Nuclear Medicine Service, Ann Arbor, MI (United States); Mariani, Giuliano [University of Pisa, Regional Center of Nuclear Medicine, Pisa (Italy); Al-Nahhas, Adil [Hammersmith Hospital, Department of Nuclear Medicine, London (United Kingdom)

    2007-06-15

    Primary hyperparathyroidism (PHPT) is an increasingly diagnosed disease worldwide. In most cases, PHPT is related to the presence of a solitary parathyroid adenoma (PA). Fifty percent or more of newly diagnosed PHPT patients are asymptomatic, and there is debate among endocrinologists and endocrine surgeons about whether or not such patients should be treated. Usually, in a PHPT patient with a solitary PA that is well localised pre-operatively, a parathyroidectomy with limited or minimally invasive neck exploration is offered. The diffusion of minimally invasive neck exploration procedures is a consequence of the significant improvement in the accuracy of pre-operative imaging (mainly scintigraphic) techniques; these techniques have changed the surgical strategy to PHPT, from the wide traditional bilateral neck exploration to limited neck exploration. The present review considers developments during the past 10-15 years with regard to both the accuracy of pre-operative localising imaging techniques and intra-operative minimally invasive procedures in order to provide endocrinologists and endocrine surgeons with further information about the newly available diagnostic and therapeutic tools for use in PHPT patients with a solitary PA. (orig.)

  18. Radiation therapy for operable rectal cancer

    International Nuclear Information System (INIS)

    Bondar, G.V.; Semikoz, N.G.; Bashejev, V.Kh.; Borota, O.V.; Bondarenko, M.V.; Kiyashko, O.Yu.

    2012-01-01

    The authors present a review of the literature on modern tendencies of radiation therapy application to treatment of operable rectal cancer. Many randomized control studies compared the efficacy of combination of radiation therapy (pre-operative or post-operative) and surgery versus surgery only demonstrating various results. Meta-analysis of the data on efficacy of combination of radiation therapy and standard surgery revealed 22 randomized control studies (14 with pre-operative radiation therapy and 8 with post-operative radiation therapy) with total number of 8507 patients (Colorectal Cancer Collaborative Group, 2000). The use of combination treatment reduced the number of isolated locoregional relapses both with pre-operative (22.5 - 12.5 %; p < 0.00001) and post-operative radiation therapy (25.8 - 16.7 %; p - 0.00001). The influence on total survival was not significant (62 % vs. 63 %; p - 0.06).

  19. Intra-operative nuclear imaging based on positron-emitting radiotracers

    International Nuclear Information System (INIS)

    Shakir, Dzhoshkun Ismail

    2014-01-01

    Positron-emitting radiotracers are an important part of nuclear medical imaging processes. Besides the very famous glucose analog [ 18 F]FDG, many not so well known ones exist, among them the particularly interesting amino acid-based tracers like [ 18 F]FET. Although peri-operative imaging with positron-emitting radiotracers has become state-of- the-art in cases of many types of cancer, their capability is not fully exploited in the operating room yet. In this thesis we explore two intra-operative nuclear imaging modalities exploiting different aspects of positron radiation towards quality assurance in challenging surgical treatment scenarios. The first modality freehand PET provides a tomographic image of a volume of interest and aims at minimizing invasiveness by assisting the surgeon in pinpointing target structures marked with a radiotracer. The second imaging modality epiphanography generates an image of the radiotracer distribution on a surface of interest and aims at providing a means for improving the control of tumor resection margins. The word epiphanography is a compound of the Greek words επιφανεια (epiphaneia) for surface and ζωγραφια (ographia) for image, and hence means the image of the surface similar to the compound τομοζ (tomos) for slice/volume and ζωγραφια (ographia) for image, meaning the image of the volume, i.e. tomography. To our knowledge this is the first use of the word epiphanography in the context of nuclear medical imaging. In this thesis we present our approach to modeling, developing and calibrating these two novel imaging modalities. In addition, we present our work towards their clinical integration. In the case of freehand PET, we have already acquired the first intra-operative datasets of a patient. We present this first experience in the operating room together with our phantom studies. In the case of epiphanography, we present our phantom studies with neurosurgeons towards the integration of this

  20. Intra-Operational Area Coordination: The Zone EOC Concept

    Science.gov (United States)

    2015-09-01

    critical infrastructure, including regional mass transportation corridors, as well as gas, electric , fuel, and water utility lines.5 Any earthquakes ...more effective alternate model and offers an alternative, multilateral collaborative model solution—the zone EOC concept. Designed to enable...Operations Center (DOC), operational area, emergency response coordination, mutual aid, catastrophic disasters, earthquake , geographic regions, emergency

  1. Automatic Adjustments of a Trans-oesophageal Ultrasound Robot for Monitoring Intra-operative Catheters

    Science.gov (United States)

    Wang, Shuangyi; Housden, James; Singh, Davinder; Rhode, Kawal

    2017-12-01

    3D trans-oesophageal echocardiography (TOE) has become a powerful tool for monitoring intra-operative catheters used during cardiac procedures in recent years. However, the control of the TOE probe remains as a manual task and therefore the operator has to hold the probe for a long period of time and sometimes in a radiation environment. To solve this problem, an add-on robotic system has been developed for holding and manipulating a commercial TOE probe. This paper focuses on the application of making automatic adjustments to the probe pose in order to accurately monitor the moving catheters. The positioning strategy is divided into an initialization step based on a pre-planning method and a localized adjustments step based on the robotic differential kinematics and related image servoing techniques. Both steps are described in the paper along with simulation experiments performed to validate the concept. The results indicate an error less than 0.5 mm for the initialization step and an error less than 2 mm for the localized adjustments step. Compared to the much bigger live 3D image volume, it is concluded that the methods are promising. Future work will focus on evaluating the method in the real TOE scanning scenario.

  2. A novel intra-operative positron imager for rapid localization of tumor margins

    Science.gov (United States)

    Sabet, Hamid; Stack, Brendan C.; Nagarkar, Vivek V.

    2014-03-01

    We have developed an intra-operative and compact imaging tool for surgeons to detect PET- positive lesions. Currently, most such probes on the market are non-imaging, and provide no ancillary information of surveyed areas, such as clear delineations of malignant tissues. Our probe consists of a novel hybrid scintillator coupled to a compact silicon photomultiplier (SiPM) array with associated front-end electronics encapsulated in an ergonomic housing. Pulse shape discrimination electronics has been implemented and integrated into the downstream data acquisition system. The hybrid scintillator consists of a 0.4 mm thick layer of CsI:Tl scintillator coupled to a 1 mm thick LYSO crystal. To achieve high spatial resolution, CsI:Tl is pixelated to 0.5×0.5 mm2 pixels using laser ablation technique. While CsI:Tl act as beta-sensitive scintillator, LYSO senses the gamma radiation and can be used to navigate the probe to the locations of interest. The gamma response is also subtracted from the beta image for improved SNR and contrast. To achieve accurate centroid position estimation and uniform beta sensitivity over the entire imaging area, the LYSO thickness is optimized such that it acts as scintillation light diffuser by spreading CsI:Tl light over multiple SiPM pixels. The results show that the response of the two scintillators exposed to radiation could be easily distinguished based on their pulse shapes. The probe's spatial resolution is beta radiation even in presence of strong gamma background.

  3. Agreement between pre-operative and intra-operative bacteriological samples in 85 chronic peri-prosthetic infections.

    Science.gov (United States)

    Matter-Parrat, V; Ronde-Oustau, C; Boéri, C; Gaudias, J; Jenny, J-Y

    2017-04-01

    Whether pre-operative microbiological sampling contributes to the management of chronic peri-prosthetic infection remains controversial. We assessed agreement between the results of pre-operative and intra-operative samples in patients undergoing single-stage prosthesis exchange to treat chronic peri-prosthetic infection. Agreement between pre-operative and intra-operative samples exceeds 75% in patients undergoing single-stage exchange of a hip or knee prosthesis to treat chronic peri-prosthetic infection. This single-centre retrospective study included 85 single-stage prosthesis exchange procedures in 82 patients with chronic peri-prosthetic infection at the hip or knee. Agreement between pre-operative and intra-operative sample results was evaluated. Changes to the initial antibiotic regimen made based on the intra-operative sample results were recorded. Of 149 pre-operative samples, 109 yielded positive cultures, in 75/85 cases. Of 452 intra-operative samples, 354 yielded positive cultures, in 85/85 cases. Agreement was complete in 54 (63%) cases and partial in 9 (11%) cases; there was no agreement in the remaining 22 (26%) cases. The complete agreement rate was significantly lower than 75% (P=0.01). The initial antibiotic regimen was inadequate in a single case. Pre-operative sampling may contribute to the diagnosis of peri-prosthetic infection but is neither necessary nor sufficient to confirm the diagnosis and identify the causative agent. The spectrum of the initial antibiotic regimen cannot be safely narrowed based on the pre-operative sample results. We suggest the routine prescription of a probabilistic broad-spectrum antibiotic regimen immediately after the prosthesis exchange, even when a pathogen was identified before surgery. IV, retrospective study. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  4. Intra-Operative Amylase Concentration in Peri-Pancreatic Fluid Predicts Pancreatic Fistula After Distal Pancreatectomy

    NARCIS (Netherlands)

    Nahm, C.B.; Reuver, P.R.; Hugh, T.J.; Pearson, A.; Gill, A.J.; Samra, J.S.; Mittal, A.

    2017-01-01

    Post-operative pancreatic fistula (POPF) is a potentially severe complication following distal pancreatectomy. The aim of this study was to assess the predictive value of intra-operative amylase concentration (IOAC) in peri-pancreatic fluid after distal pancreatectomy for the diagnosis of POPF.

  5. l-Arginine Pathway Metabolites Predict Need for Intra-operative Shunt During Carotid Endarterectomy

    DEFF Research Database (Denmark)

    Szabo, P; Lantos, J; Nagy, L

    2016-01-01

    lactate levels were increased during reperfusion (p = .02). The median pre-operative concentration of l-arginine was lower in patients requiring an intra-operative shunt than in patients without need of shunt (median: 30.3 μmol/L [interquartile range 24.4-34.4 μmol/L] vs. 57.6 μmol/L [interquartile range...

  6. Relevance of intra operative radiotherapy in the treatment of uterine carcinoma - Lyon preliminary experience

    International Nuclear Information System (INIS)

    Gerard, J.P.; Braillon, G.; Gilly, F.N.; Romestaing, P.; Sentenac, I.; Rocher, F.P.; Berger, C.; Chipier, V.; Dargent, D.; Chabert, P.; Raudrant, D.; Adeleine, P.

    1994-01-01

    Aim: Retrospective analysis of Intra operative Radiotherapy (IORT) in recurrent uterine carcinoma (RUC) and prospective pilot study of IORT in advanced cervix cancer (ACC) with high risk of local failure. Patients-Treatments: (1) RUC: from 1988 to 1991, 34 patients with RUC have been treated. Primary cancer was: cervix uterus: 28, endometrium: six. Site of recurrence: centro pelvis: four, latero pelvis: 25, lombo aortic: five. Total gross resection was only possible in 12 patients. A dose of 15 to 22 Gy was given by IORT according to the residual tumour size. External beam irradiation was added in 16 patients; (2) ACC: January 1991 to November 1992, 20 patients were included in this pilot study, stage IIB: seven, stage III: 12, stage IV: 1. Preoperative retroperitoneal pelviscopy showed 13 pN1 patients and NMR imaging ten tumours of 6 cm or larger in diameter. Treatment started with concomitant pelvic irradiation (44 Gy) and one concomitant cycle of 5 Fu-CDDP, followed by a short course of high dose rate upper vagina brachytherapy (4Gy). Four weeks later a radical Wertheim operation was performed together with IORT on the lateral pelvis. Results: (1) RUC: overall survival (Kaplan Meier) at 4 years is 32% (±8). Local relapse in the field of IORT was observed in six patients. Grade 2-3 complications: six patients (radiation proctitis, neuritis, vertebral collapse, ureteral stenosis); (2) ACC: the median follow up is short (18 months). Four cases of pelvic relapse, no postoperative death. The first line radio chemotherapy was associated with two G3 early complications. Postoperative radiation complication was less than 10% G3. Discussion: promising results of IORT in RUC have been observed especially if no irradiation is given during the primary treatment. Good feasibility of the pilot study of IORT in ACC was also observed. It could be followed by a multicentric feasibility trial. (authors). 38 refs., 4 tabs., 1 fig

  7. Radiation therapy with concurrent retrograde superselective intra-arterial chemotherapy for gingival carcinoma

    International Nuclear Information System (INIS)

    Mukai, Y.; Hata, M.; Koike, I.; Inoue, T.; Mitsudo, K.; Koizumi, T.; Oguri, S.; Kioi, M.; Tohnai, I.; Omura, M.

    2014-01-01

    The aim of this study was to review the efficacy and toxicity of radiation therapy with concurrent retrograde superselective intra-arterial chemotherapy in the treatment of gingival carcinoma. In all, 34 patients (21 men and 13 women) with squamous cell carcinoma of the gingiva underwent radiation therapy with concurrent retrograde superselective intra-arterial chemotherapy. Treatment consisted of daily external irradiation and concurrent retrograde superselective intra-arterial infusion with cisplatin and docetaxel. A median total dose of 60 Gy in 30 fractions was delivered to tumors. Of the 34 patients, 29 (85 %) achieved a complete response (CR) and 5 had residual tumors. Of the 29 patients with a CR, 2 had local recurrences and 1 had distant metastasis 1-15 months after treatment. Twenty-six of the 36 patients had survived at a median follow-up time of 36 months (range 12-79 months); 4 died of cancer and 4 died of non-cancer-related causes. At both 3 and 5 years after treatment, the overall survival rates were 79 % and the cause-specific survival rates were 85 %. Osteoradionecrosis of the mandibular bone only developed in 1 patient after treatment. Radiation therapy with concurrent retrograde superselective intra-arterial chemotherapy was effective and safe in the treatment of gingival carcinoma. This treatment may be a promising curative and organ-preserving treatment option for gingival carcinoma. (orig.) [de

  8. aging hypotension and intra-operative cardiac arres

    African Journals Online (AJOL)

    Initiate CPR. Call for defibrillator. Instruct surgeon to deliver foetus. All to follow instructions. Can ask: “what must I do?” *Times given are approximate values for ..... Functioning of operating table. 4. 4. 4. Neonatal equipment. Indicate that neonatal equipment must be checked. 0. 3. 4. Preoperative assessment. Medical and ...

  9. Intra-operative parathyroid hormone measurements – experience of ...

    African Journals Online (AJOL)

    These patients remained normocalcaemic during follow-up. The 'uncured' patient was operated on by means of a targeted approach to the left lower parathyroid, based on the result of the sestamibi scan. His medical history comprised previous thy- roid gland surgery. After removal of what appeared to be thyroid tissue, the ...

  10. Presentation of the GIE INTRA Group's operational means; Presentation des moyens operationnels du GIE Groupe Intra

    Energy Technology Data Exchange (ETDEWEB)

    Cochard, A. [Directeur general du GIE Groupe Intra, BP 61 - 37420 Avoine (France)

    2010-07-01

    Located on the Chinon nuclear power plant site, the Intra Group is an economic interest grouping which has been created by the three French nuclear operators (EDF, CEA, and COGEMA now AREVA) after the Chernobyl accident. Its missions are to possess permanently available means of intervention in case of severe accident or radiological situation, to be able to intervene at any time on the French territory, to develop a European network of expertise, and to build up an ability centre for robotic intervention in hostile environment. This document briefly presents its different available means: remotely controlled equipment (inside and outside equipment, public works equipment), and radiological characterization equipment. Other aspects are briefly evoked: organization, information transmission, exercises and interventions, international relationships, future trends

  11. Workflow Driven Decision Support Systems : A case of an intra-operative visualization system for surgeons

    NARCIS (Netherlands)

    Jalote-Parmar, A.

    2009-01-01

    Inadequate visualization during Minimally Invasive Surgeries (MIS) has led several technology research labs to develop decision support systems such as Intra-operative Visualization Systems (IVS). IVS focuses on providing surgeons with real-time imaging support to improve task visualization and

  12. Photoacoustic intra-operative nodal staging using clinically approved superparamagnetic iron oxide nanoparticles

    NARCIS (Netherlands)

    Grootendorst, Diederik; Fratila, R.M.; Visscher, M.; ten Haken, Bernard; van Wezel, Richard Jack Anton; Steenbergen, Wiendelt; Manohar, Srirang; Ruers, Theo J.M.; Oraevsky, Alexander A.; Wang, Lihong V.

    2013-01-01

    Detection of tumor metastases in the lymphatic system is essential for accurate staging of various malignancies, however fast, accurate and cost-effective intra-operative evaluation of the nodal status remains difficult to perform with common available medical imaging techniques. In recent years,

  13. Evaluation of measures to decrease intra-operative bacterial contamination in orthopaedic implant surgery

    NARCIS (Netherlands)

    Knobben, BAS; van Horn, [No Value; van der Mei, HC; Busscher, HJ

    The aim of this study was to evaluate whether behavioural and systemic measures wilt decrease intra-operative contamination during total hip or knee replacements. The influence of these measures on subsequent prolonged wound discharge, superficial surgical site infection and deep periprosthetic

  14. Effect of intra-operative glove changing during cesarean section on post-operative complications: a randomized controlled trial.

    Science.gov (United States)

    Scrafford, Jonathan D; Reddy, Buvana; Rivard, Colleen; Vogel, Rachel Isaksson

    2018-03-19

    To compare the rates of wound-related complications among women undergoing a cesarean section when the surgical team used intra-operative glove changing versus usual care. All women undergoing a cesarean section at a single, county hospital were randomized to usual care or intra-operative glove changing prior to abdominal closure. Participants were randomized at the time of decision for cesarean section; surgeons were not blinded to the randomization arm. The primary outcome was any wound-related complication, including wound hematoma, seroma, skin separation of at least 1 cm, wound infection, or other incisional abnormality requiring treatment within 8 weeks of surgery. To detect a reduction in the primary outcome from 17% in the control group to 9% in the intervention group with 80% power, a total of 554 women (277 per group) were required. Secondary outcomes included other infectious complications including endometritis and other superficial or deep soft tissue infections. From August 2015 to November 2016, 277 women were randomized to usual care and 276 women were randomized to intra-operative glove changing. The two groups were well balanced in terms of demographic data, comorbid conditions and surgical characteristics. Intra-operative glove changing led to a significant decrease in composite wound complications from 13.6% in the control group to 6.4% in the intervention group (p = 0.008). Intra-operative glove changing prior to abdominal closure during cesarean section significantly reduced the incidence of post-operative wound complications.

  15. Effects of intra-operative fluoroscopic 3D-imaging on peri-operative imaging strategy in calcaneal fracture surgery

    NARCIS (Netherlands)

    M.S.H. Beerekamp (Suzan); Backes, M. (M.); N.W.L. Schep (Niels); D.T. Ubbink (Dirk); J.S.K. Luitse; T. Schepers (Tim); J.C. Goslings (Carel)

    2017-01-01

    textabstractIntroduction: Previous studies demonstrated that intra-operative fluoroscopic 3D-imaging (3D-imaging) in calcaneal fracture surgery is promising to prevent revision surgery and save costs. However, these studies limited their focus to corrections performed after 3D-imaging, thereby

  16. Studies on the reliability of high-field intra-operative MRI in brain glioma resection

    Directory of Open Access Journals (Sweden)

    Zhi-jun SONG

    2011-07-01

    Full Text Available Objective To evaluate the reliability of high-field intra-operative magnetic resonance imaging(iMRI in detecting the residual tumors during glioma resection.Method One hundred and thirty-one cases of brain glioma(69 males and 62 females,aged from 7 to 79 years with mean of 39.6 years hospitalized from Nov.2009 to Aug.2010 were involved in present study.All the patients were evaluated using magnetic resonance imaging(MRI before the operation.The tumors were resected under conventional navigation microscope,and the high-field iMRI was used for all the patients when the operators considered the tumor was satisfactorily resected,while the residual tumor was difficult to detect under the microscope,but resected after being revealed by high-field iMRI.Histopathological examination was performed.The patients without residual tumors recieved high-field MRI scan at day 4 or 5 after operation to evaluate the accuracy of high-field iMRI during operation.Results High quality intra-operative images were obtained by using high-field iMRI.Twenty-eight cases were excluded because their residual tumors were not resected due to their location too close to functional area.Combined with the results of intra-operative histopathological examination and post-operative MRI at the early recovery stage,the sensitivity of high-field iMRI in residual tumor diagnosis was 98.0%(49/50,the specificity was 94.3%(50/53,and the accuracy was 96.1%(99/103.Conclusion High-quality intra-operative imaging could be acquired by high-field iMRI,which maybe used as a safe and reliable method in detecting the residual tumors during glioma resection.

  17. Radiation safety in aircraft operations

    Science.gov (United States)

    Wilson, J. W.; Nealy, J. E.

    1992-01-01

    Data from a 7-yr flight experiment program to measure the significant biological components (tissue ionization rates, neutron flux, and nuclear reaction star rates) as a function of solar cycle, altitude, latitude and longitude from which biological risk from radiation is estimated are used to evaluate radiation dose and dose equivalents along specific flight trajectories. The data base used and the corresponding time-dependent global model are described. Ionization rates in air measured by argon filled chambers at solar minimum and maximum, and radiation measurements of the Brookhaven National Laboratory instrument compared to the present model are illustrated in tabular form. The global pressure distribution for solstice conditions at 14 km is shown.

  18. Middle cerebral artery aneurysms: aneurysm angiographic morphology and its relation to pre-operative and intra-operative rupture

    Directory of Open Access Journals (Sweden)

    Iracema Araújo Estevão

    Full Text Available ABSTRACT Objective Correlate the middle cerebral artery bifurcation aneurysm morphology with the pre-operative and intra-operative risk of rupture. Methods Forty patients with 46 middle cerebral artery bifurcation aneurysms were treated microsurgically by the same surgeon. Aneurysms were classified according to shape and the Fisher test was applied to analyze the effect of morphology on the pre-operative and intra-operative rupture. Results Pre-operative and intra-operative ruptures were observed in 8/46 patients (17.4% and 14/46 patients (30.4% respectively. Thirty-two cases (69.6% had no symptoms postoperatively, modified Rankin score (MRS of 0; 6.5% had MRS of 1 (no significant disability; 13% had MRS of 2 (slight disability; 4.3% had moderately severe disability (MRS of 4; and there were 3 deaths (6.5% post-operatively. The morphology was not directly related to the rupture rate. Conclusion In general, ruptures are not affected by the morphology or the studied variables. Larger series are needed to validate these outcomes.

  19. Intra-operative measurement of applied forces during anterior scoliosis correction.

    Science.gov (United States)

    Fairhurst, H; Little, J P; Adam, C J

    2016-12-01

    Spinal instrumentation and fusion for the treatment of scoliosis is primarily a mechanical intervention to correct the deformity and halt further progression. While implant-related complications remain a concern, little is known about the magnitudes of the forces applied to the spine during surgery, which may affect post-surgical outcomes. In this study, the compressive forces applied to each spinal segment during anterior instrumentation were measured in a series of patients with Adolescent Idiopathic Scoliosis. A force transducer was designed and retrofit to a routinely used surgical tool, and compressive forces applied to each segment during surgery were measured for 15 scoliosis patients. Cobb angle correction achieved by each force was measured on intra-operative fluoroscope images. Relative changes in orientation of the screw within the vertebra were also measured to detect intra-operative screw plough. Intra-operative forces were measured for a total of 95 spinal segments. The mean applied compressive force was 540N (SD 230N, range 88N-1019N). There was a clear trend for higher forces to be applied at segments toward the apex of the scoliosis. Fluoroscopic evidence of screw plough was detected at 10 segments (10.5%). The magnitude of forces applied during anterior scoliosis correction vary over a broad range. These forces do reach magnitudes capable of causing intra-operative vertebral body screw plough. Surgeons should be aware there is a risk for tissue overload during correction, however the clinical implications of intra-operative screw plough remain unclear. The dataset presented here is valuable for providing realistic input parameters for in silico surgical simulations. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Use of virtual slide system for quick frozen intra-operative telepathology diagnosis in Kyoto, Japan.

    Science.gov (United States)

    Tsuchihashi, Yasunari; Takamatsu, Terumasa; Hashimoto, Yukimasa; Takashima, Tooru; Nakano, Kooji; Fujita, Setsuya

    2008-07-15

    We started to use virtual slide (VS) and virtual microscopy (VM) systems for quick frozen intra-operative telepathology diagnosis in Kyoto, Japan. In the system we used a digital slide scanner, VASSALO by CLARO Inc., and a broadband optic fibre provided by NTT West Japan Inc. with the best effort capacity of 100 Mbps. The client is the pathology laboratory of Yamashiro Public Hospital, one of the local centre hospitals located in the south of Kyoto Prefecture, where a full-time pathologist is not present. The client is connected by VPN to the telepathology centre of our institute located in central Kyoto. As a result of the recent 15 test cases of VS telepathology diagnosis, including cases judging negative or positive surgical margins, we could estimate the usefulness of VS in intra-operative remote diagnosis. The time required for the frozen section VS file making was found to be around 10 min when we use x10 objective and if the maximal dimension of the frozen sample is less than 20 mm. Good correct focus of VS images was attained in all cases and all the fields of each tissue specimen. Up to now the capacity of best effort B-band appears to be sufficient to attain diagnosis on time in intra-operation. Telepathology diagnosis was achieved within 5 minutes in most cases using VS viewer provided by CLARO Inc. The VS telepathology system was found to be superior to the conventional still image telepathology system using a robotic microscope since in the former we can observe much greater image information than in the latter in a certain limited time of intra-operation and in the much more efficient ways. In the near future VS telepathology will replace conventional still image telepathology with a robotic microscope even in quick frozen intra-operative diagnosis.

  1. Outcome of renal transplantation with and without intra-operative diuretics.

    Science.gov (United States)

    Hanif, F; Macrae, A N; Littlejohn, M G; Clancy, M J; Murio, E

    2011-01-01

    This paper presents an e-survey of current clinical practice of use of intra-operative diuretics during renal transplantation in the United Kingdom and a study to compare outcome of renal transplants carried out with or without intra-operative diuretics in our centre. An e-mail questionnaire to renal transplant surgeons exploring their practice of renal transplantation with or without intra-operative diuretics, the type of a diuretic/s if used and the relevant doses. An observational study comparing the outcome of renal transplant recipients, group no-diuretics (GND, n = 80) carried out from 2004 to 2008 versus group diuretics (GD n = 69) renal transplant recipients who received intra-operative diuretics over a one year period is presented. Outcome measures were incidence of delayed graft function and a comparison of graft survival in both groups. Forty surgeons answered from 18 transplant centres with a response rate of 67%. 13 surgeons do not use diuretics. Mannitol is used by 10/40, Furosemide 6/40 and 11 surgeons use a combination of both. In comparative study there was no significant overall difference in one year graft survival of GD versus GND (N = 65/69, 94% and 75/80, 94% respectively, p = 0.08) and the incidence of delayed graft function was also comparable (16/69, 23% and 21/80, 26% respectively, p = 0.07). The donor characteristics in both groups were comparable. The study showed variation in clinical practice on the use of intra-operative diuretics in renal transplantation and it did not demonstrate that the use of diuretics can improve renal graft survival. Copyright © 2011 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

  2. Bimanual, intra-operative, fluoroscopy-guided removal of nasopharyngeal migratory fish bone from carotid space.

    Science.gov (United States)

    Al-Abduwani, J A; Bhargava, D; Sawhney, S; Al-Abri, R

    2010-07-01

    We report a rare and unusual case of a patient with an ingested fishbone which migrated from the oropharynx to the anterior compartment of the retropharyngeal space and then to the deep neck space in the nasopharynx (i.e. the carotid space). This report aims to describe a successful, minimally invasive method of foreign body removal which avoided both major skull base surgery and any potential life-threatening complications. A secondary aim is to highlight the role of intra-operative fluoroscopy, an under-used tool. We present a 67-year-old man with a history of fish bone impaction but no fish bone visible on plain X-ray or flexible endoscopy. The diagnosis of fish bone lodged in the retropharyngeal space was confirmed by computed tomography. Surgical exploration of the anterior retropharyngeal space failed to locate the fish bone, as it had migrated to a new, unknown location. Intra-operative fluoroscopy was vital for the removal of the fish bone, as it was impossible to see with the naked eye and had migrated from its previously imaged position. The fish bone was finally retrieved bimanually using external pressure on the submandibular region, which displaced the fish bone, and fluoroscopic guidance, which assisted its removal from the nasopharyngeal lumen. To the best of our knowledge, this is the first reported case of bimanual, intra-operative, fluoroscopy-guided, intra-luminal removal of a migratory fish bone from the deep neck space in this region of the nasopharynx.

  3. The effect of Kombucha on post-operative intra-abdominal adhesion formation in rats.

    Science.gov (United States)

    Maghsoudi, Hemmat; Mohammadi, Hussein Benagozar

    2009-04-01

    Peritoneal adhesions are fibrous bands of tissues formed between organs that are normally separated and/or between organs and the internal body wall after peritoneal injury. The aim of the study was to investigate the effect of intra-peritoneal administration of Kombucha on intra-peritoneal adhesions. Eighty Wistar rats were subjected to standardized lesion by scraping model and were randomly divided into two groups. Group I received no treatment, and Group II received 15 ml of Kombucha solution intra-peritoneally. On the post-operative 14th day adhesion intensity score, inflammatory cell reaction and number of adhesion bands were determined. In the control group, there were no rats with grade 0 and I adhesions. In the group II, there were 26 rats (78.8%) with grade 0-2 adhesions. Adhesion intensity was significantly less in group II (PKombucha might be useful for preventing peritoneal adhesions.

  4. Safe surgery: how accurate are we at predicting intra-operative blood loss?

    LENUS (Irish Health Repository)

    2012-02-01

    Introduction Preoperative estimation of intra-operative blood loss by both anaesthetist and operating surgeon is a criterion of the World Health Organization\\'s surgical safety checklist. The checklist requires specific preoperative planning when anticipated blood loss is greater than 500 mL. The aim of this study was to assess the accuracy of surgeons and anaesthetists at predicting intra-operative blood loss. Methods A 6-week prospective study of intermediate and major operations in an academic medical centre was performed. An independent observer interviewed surgical and anaesthetic consultants and registrars, preoperatively asking each to predict expected blood loss in millilitre. Intra-operative blood loss was measured and compared with these predictions. Parameters including the use of anticoagulation and anti-platelet therapy as well as intra-operative hypothermia and hypotension were recorded. Results One hundred sixty-eight operations were included in the study, including 142 elective and 26 emergency operations. Blood loss was predicted to within 500 mL of measured blood loss in 89% of cases. Consultant surgeons tended to underestimate blood loss, doing so in 43% of all cases, while consultant anaesthetists were more likely to overestimate (60% of all operations). Twelve patients (7%) had underestimation of blood loss of more than 500 mL by both surgeon and anaesthetist. Thirty per cent (n = 6\\/20) of patients requiring transfusion of a blood product within 24 hours of surgery had blood loss underestimated by more than 500 mL by both surgeon and anaesthetist. There was no significant difference in prediction between patients on anti-platelet or anticoagulation therapy preoperatively and those not on the said therapies. Conclusion Predicted intra-operative blood loss was within 500 mL of measured blood loss in 89% of operations. In 30% of patients who ultimately receive a blood transfusion, both the surgeon and anaesthetist significantly underestimate

  5. Operative versus non-operative treatment for closed, displaced, intra-articular fractures of the calcaneus: randomised controlled trial.

    Science.gov (United States)

    Griffin, Damian; Parsons, Nick; Shaw, Ewart; Kulikov, Yuri; Hutchinson, Charles; Thorogood, Margaret; Lamb, Sarah E

    2014-07-24

    To investigate whether surgery by open reduction and internal fixation provides benefit compared with non-operative treatment for displaced, intra-articular calcaneal fractures. Pragmatic, multicentre, two arm, parallel group, assessor blinded randomised controlled trial (UK Heel Fracture Trial). 22 tertiary referral hospitals, United Kingdom. 151 patients with acute displaced intra-articular calcaneal fractures randomly allocated to operative (n=73) or non-operative (n=78) treatment. The primary outcome measure was patient reported Kerr-Atkins score for pain and function (scale 0-100, 100 being the best possible score) at two years after injury. Secondary outcomes were complications; hindfoot pain and function (American Orthopaedic Foot and Ankle Society score); general health (SF-36); quality of life (EQ-5D); clinical examination; walking speed; and gait symmetry. Analysis was by intention to treat. 95% follow-up was achieved for the primary outcome (69 in operative group and 74 in non-operative group), and a complete set of secondary outcomes were available for 75% of participants. There was no significant difference in the primary outcome (mean Kerr-Atkins score 69.8 in operative group v 65.7 in non-operative group; adjusted 95% confidence interval of difference -7.1 to 7.0) or in any of the secondary outcomes between treatment groups. Complications and reoperations were more common in those who received operative care (estimated odds ratio 7.5, 95% confidence interval 2.0 to 41.8). Operative treatment compared with non-operative care showed no symptomatic or functional advantage after two years in patients with typical displaced intra-articular fractures of the calcaneus, and the risk of complications was higher after surgery. Based on these findings, operative treatment by open reduction and internal fixation is not recommended for these fractures.Trial registration Current Controlled Trials ISRCTN37188541. © Griffin et al 2014.

  6. Doppler ultrasonography in living donor liver transplantation recipients: Intra- and post-operative vascular complications.

    Science.gov (United States)

    Abdelaziz, Omar; Attia, Hussein

    2016-07-21

    Living-donor liver transplantation has provided a solution to the severe lack of cadaver grafts for the replacement of liver afflicted with end-stage cirrhosis, fulminant disease, or inborn errors of metabolism. Vascular complications remain the most serious complications and a common cause for graft failure after hepatic transplantation. Doppler ultrasound remains the primary radiological imaging modality for the diagnosis of such complications. This article presents a brief review of intra- and post-operative living donor liver transplantation anatomy and a synopsis of the role of ultrasonography and color Doppler in evaluating the graft vascular haemodynamics both during surgery and post-operatively in accurately defining the early vascular complications. Intra-operative ultrasonography of the liver graft provides the surgeon with useful real-time diagnostic and staging information that may result in an alteration in the planned surgical approach and corrections of surgical complications during the procedure of vascular anastomoses. The relevant intra-operative anatomy and the spectrum of normal and abnormal findings are described. Ultrasonography and color Doppler also provides the clinicians and surgeons early post-operative potential developmental complications that may occur during hospital stay. Early detection and thus early problem solving can make the difference between graft survival and failure.

  7. Operation control device under radiation exposure

    International Nuclear Information System (INIS)

    Kimura, Kiichi; Murakami, Toichi.

    1994-01-01

    The device of the present invention performs smooth progress of operation by remote control for a plurality of operations in periodical inspections in controlled areas of a nuclear power plant, thereby reducing the operator's exposure dose. Namely, the device monitors the progressing state of the operation by displaying the progress of operation on a CRT of a centralized control device present in a low dose area remote from an operation field through an ITV camera disposed in the vicinity of the operation field. Further, operation sequence and operation instruction procedures previously inputted in the device are indicated to the operation field through an operation instruction outputting device (field CRT) in accordance with the progress of the operation steps. On the other hand, the operation progress can be aided by inputting information from the operation field such as start or completion of the operation steps. Further, the device of the present invention can monitor the change of operation circumstances and exposure dose of operators based on the information from a radiation dose measuring device disposed in the operation circumstance and to individual operators. (I.S.)

  8. Touch imprint and crash preparation intra operative cytology versus frozen section in thyroid nodule

    Directory of Open Access Journals (Sweden)

    Ali Chehrei

    2012-01-01

    Full Text Available Background: Intra operative cytology (IC, including touch imprint (TI and crash preparations (CP, in general has been demonstrated to be a diagnostic tool for many organs but its validity and reliability for diagnosis of thyroid nodules remain controversial. We evaluate the diagnostic value of frozen section, touch imprint, crash preparation and the combination of touch imprint and crash preparation and the combination of frozen section, touch imprint and crash preparation. Materials ans Methods : 55 intra operative specimens from patients with thyroid nodules who underwent thyroidectomy were evaluated at Alzahra and vali-Asr hospital laboratories. For all of the patients frozen section (FS, touch imprint (TI and crash preparation (CP was obtained and reviewed by two pathologists at the same time. Serial TI and CP, and FS, TI and CP were reviewed by the same pathologists. Sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio, negative likelihood ratio and accuracy were calculated according to the permanent section as the gold standard test. Results: In our study sensitivity, specificity and accuracy for FS was 100%, 97.6% and 98.1% respectively; for TI they were 78.6%, 95% and 92.4%; for CP they were 78.6%, 92.7% and 89.9%; for serial TI and CP they were 85.7%, 92.7% and 90.9%; and for the combination of FS and TI and CP they were 100%, 97.6% and 98.18% respectively. Conclusions: Intra operative cytology (including TI and CP seems to be a useful, valuable and inexpensive method in clinics, which do not have equipment for frozen sections. Intra operative cytology combined with FS increased the overall accuracy of diagnosis. Further studies are needed to validate the obtained results of this study.

  9. Intra-operative mapping of the atria: the first step towards individualization of atrial fibrillation therapy?

    Science.gov (United States)

    Kik, Charles; Mouws, Elisabeth M J P; Bogers, Ad J J C; de Groot, Natasja M S

    2017-07-01

    Atrial fibrillation (AF), an age-related progressive disease, is becoming a worldwide epidemic with a prevalence rate of 33 million. Areas covered: In this expert review, an overview of important results obtained from previous intra-operative mapping studies is provided. In addition, our novel intra-operative high resolution mapping studies, its surgical considerations and data analyses are discussed. Furthermore, the importance of high resolution mapping studies of both sinus rhythm and AF for the development of future AF therapy is underlined by our most recent results. Expert commentary: Progression of AF is determined by the extensiveness of electropathology which is defined as conduction disorders caused by structural damage of atrial tissue. The severity of electropathology is a major determinant of therapy failure. At present, we do not have any diagnostic tool to determine the degree of electropathology in the individual patient and we can thus not select the most optimal treatment modality for the individual patient. An intra-operative, high resolution scale, epicardial mapping approach combined with quantification of electrical parameters may serve as a diagnostic tool to stage AF in the individual patient and to provide patient tailored therapy.

  10. Clinical evaluation of intra-operative radiotherapy combined with subtotal cystectomy for invasive bladder carcinoma

    International Nuclear Information System (INIS)

    Ozawa, Kazunori; Nakagomi, Kazuaki; Yonese, Junzi

    1996-01-01

    From 1981 to 1994, intra-operative radiotherapy after subtotal cystectomy was performed on 22 patients with invasive bladder carcinoma on whom radical cystectomy could not be recommended because of old age or condition. All the patients received 25 to 30 Gy of radiotherapy focused on trigonum and internal urethral orifice after subtotal cystectomy with uretero-cutaneostomy. Of 22 patients, 15 patients died. Five patients died of bladder cancer, one died of gastic cancer, one died of rectal cancer and the others died of pneumonia, heart failure, sepsis and senility. The five-year survival rate was 41% and the cause-specific five-year survival rate was 75%. Local recurrence was seen only in one patient, who received second intra-operative radiotherapy and recovered well in complete remission. We believe that intra-operative radiotherapy after subtotal cystectomy is useful for patients with invasive bladder carcinoma on whom radical cystectomy could not be recommended because of old age or condition. (author)

  11. RADCAL Operations Manual Radiation Calibration Laboratory Protocol

    Energy Technology Data Exchange (ETDEWEB)

    Bogard, J.S.

    1998-12-01

    The Life Sciences Division (LSD) of Oak Ridge National Laboratory (ORNL) has a long record of radiation dosimetry research, primarily using the Health Physics Research Reactor (HPRR) and the Radiation Calibration Laboratory (RADCAL) in its Dosimetry Applications Research (DOSAR) Program. These facilities have been used by a broad segment of the research community to perform a variety of experiments in areas including, but not limited to, radiobiology, radiation dosimeter and instrumentation development and calibration, and the testing of materials in a variety of radiation environments. Operations of the HPRR were terminated in 1987 and the reactor was moved to storage at the Oak Ridge Y-12 Plant; however, RADCAL will continue to be operated in accordance with the guidelines of the National Institute of Standards and Technology (NIST) Secondary Calibration Laboratory program and will meet all requirements for testing dosimeters under the National Voluntary Laboratory Accreditation Program (NVLAP). This manual is to serve as the primary instruction and operation manual for the Oak Ridge National Laboratory's RADCAL facility. Its purpose is to (1) provide operating protocols for the RADCAL facility, (2) outline the organizational structure, (3) define the Quality Assurance Action Plan, and (4) describe all the procedures, operations, and responsibilities for the safe and proper operation of all routine aspects of the calibration facility.

  12. Intra-Operative Amylase Concentration in Peri-Pancreatic Fluid Predicts Pancreatic Fistula After Distal Pancreatectomy.

    Science.gov (United States)

    Nahm, Christopher B; de Reuver, Philip R; Hugh, Thomas J; Pearson, Andrew; Gill, Anthony J; Samra, Jaswinder S; Mittal, Anubhav

    2017-06-01

    Post-operative pancreatic fistula (POPF) is a potentially severe complication following distal pancreatectomy. The aim of this study was to assess the predictive value of intra-operative amylase concentration (IOAC) in peri-pancreatic fluid after distal pancreatectomy for the diagnosis of POPF. Consecutive patients who underwent a distal pancreatectomy between November 2014 and September 2016 were included in the analysis. IOAC was measured, followed by drain fluid analysis for amylase on post-operative days (PODs) 1, 3, and 5. Receiver operator characteristic (ROC) analysis was performed to evaluate the discriminative capacity of IOAC as a predictor of POPF. IOAC was measured after distal pancreatectomy in 26 patients. The IOAC correlated significantly with (i) PODs 1, 3, and 5 drain amylase (p  1000 experienced a post-operative complication (OR 18.3, 95% CI 2.51-103, p pancreatectomy.

  13. Radiation therapy with concurrent retrograde superselective intra-arterial chemotherapy for gingival carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Mukai, Y.; Hata, M.; Koike, I.; Inoue, T. [Yokohama City University Graduate School of Medicine, Department of Radiology, Kanazawa-ku, Yokohama, Kanagawa (Japan); Mitsudo, K.; Koizumi, T.; Oguri, S.; Kioi, M.; Tohnai, I. [Yokohama City University Graduate School of Medicine, Department of Oral and Maxillofacial Surgery, Yokohama, Kanagawa (Japan); Omura, M. [Shonankamakura General Hospital, Department of Radiation Oncology, Kamakura, Kanagawa (Japan)

    2014-02-15

    The aim of this study was to review the efficacy and toxicity of radiation therapy with concurrent retrograde superselective intra-arterial chemotherapy in the treatment of gingival carcinoma. In all, 34 patients (21 men and 13 women) with squamous cell carcinoma of the gingiva underwent radiation therapy with concurrent retrograde superselective intra-arterial chemotherapy. Treatment consisted of daily external irradiation and concurrent retrograde superselective intra-arterial infusion with cisplatin and docetaxel. A median total dose of 60 Gy in 30 fractions was delivered to tumors. Of the 34 patients, 29 (85 %) achieved a complete response (CR) and 5 had residual tumors. Of the 29 patients with a CR, 2 had local recurrences and 1 had distant metastasis 1-15 months after treatment. Twenty-six of the 36 patients had survived at a median follow-up time of 36 months (range 12-79 months); 4 died of cancer and 4 died of non-cancer-related causes. At both 3 and 5 years after treatment, the overall survival rates were 79 % and the cause-specific survival rates were 85 %. Osteoradionecrosis of the mandibular bone only developed in 1 patient after treatment. Radiation therapy with concurrent retrograde superselective intra-arterial chemotherapy was effective and safe in the treatment of gingival carcinoma. This treatment may be a promising curative and organ-preserving treatment option for gingival carcinoma. (orig.) [German] Das Ziel dieser Studie war die Ueberpruefung der Effizienz und Toxizitaet einer Strahlenbehandlung des Gingivakarzinoms mit gleichzeitiger retrograder, superselektiver intraarterieller Chemotherapie. Insgesamt 34 Patienten (21 Maenner und 13 Frauen) mit Zahnfleischplattenzellkarzinom erhielten eine Strahlenbehandlung mit gleichzeitiger retrograder, superselektiver intraarterieller Chemotherapie. Die Behandlung umfasste eine taegliche externe Bestrahlung mit gleichzeitiger retrograder, superselektiver intraarterieller Infusion von Cisplatin und

  14. [Intra-operative myelography in treatment of fractures of thoracolumbar spine].

    Science.gov (United States)

    Tomčovčík, L; Cuha, R; Raši, R

    2010-08-01

    The aim of this retrospective study was to evaluate the results of intra-operative myelography as the method used to assess the reduction of bone fragments from the posterior margin of the vertebral body. Forty patients with 42 comminuted fractures of the thoracolumbar spine were included in the study. The pre-operative spinal stenosis caused by bone fragments from the posterior margin of the vertebral body, as detected by CT scanning, ranged from 25 % to 85 %. Neurological deficit was due to injury in 19 patients and in one it developed post-operatively after the patient stood and walked. After ligamentotaxis and internal fixation, intra-operative myelography was used to show decompression of the spinal canal. A spinal block or severe constriction of contrast flow was an indication for hemilaminectomy (laminectomy) and direct decompression of the spinal canal. In the patients with neurological deficit and severe spinal stenosis persisting after ligamentotaxis and detectable by skiascopy, hemilaminectomy (laminectomy) and direct spinal decompression followed by intra-operative myelography were carried out. Intra-operative myelography was used 46 -times (20-times in 20 patients free from neurological deficit and 26-times in 20 patients with neurological deficit). In 38 cases (82.6 %) dural sac compression was not present (patients with neurological deficit, 13-times after ligamentotaxis, eight-times after ligamentotaxis and hemilaminectomy with direct decompression, twi- ce at repeat surgeryúúú patients without neurological deficit, 15-times). On two occasions (4.4 %) the contrast agent injected into the dural sac did not make the interior body part visible, on three occasions (6.5 %) contrast medium was injected extradurally, and dural sac compression following ligamentotaxis requiring hemilaminectomy (laminectomy) and direct decompression occurred in three cases (6.5 %). In the patients without neurological deficit, dural sac compression was not recorded. No

  15. Intra-operative colloid administration increases the clearance of a post-operative fluid load

    DEFF Research Database (Denmark)

    Borup, Tine; Hahn, Robert; Holte, K

    2009-01-01

    using volume kinetics based on the plasma dilution alone. The pre-operative plasma clearance was compared with the post-operative plasma clearance and patients served as their own control. RESULTS: The urinary excretion averaged 350 ml for the pre-operative infusion and 612 ml post-operatively, which...

  16. A Novel Stress-Diathesis Model to Predict Risk of Post-operative Delirium: Implications for Intra-operative Management

    Directory of Open Access Journals (Sweden)

    Renée El-Gabalawy

    2017-08-01

    Full Text Available Introduction: Risk assessment for post-operative delirium (POD is poorly developed. Improved metrics could greatly facilitate peri-operative care as costs associated with POD are staggering. In this preliminary study, we develop a novel stress-diathesis model based on comprehensive pre-operative psychiatric and neuropsychological testing, a blood oxygenation level-dependent (BOLD magnetic resonance imaging (MRI carbon dioxide (CO2 stress test, and high fidelity measures of intra-operative parameters that may interact facilitating POD.Methods: The study was approved by the ethics board at the University of Manitoba and registered at clinicaltrials.gov as NCT02126215. Twelve patients were studied. Pre-operative psychiatric symptom measures and neuropsychological testing preceded MRI featuring a BOLD MRI CO2 stress test whereby BOLD scans were conducted while exposing participants to a rigorously controlled CO2 stimulus. During surgery the patient had hemodynamics and end-tidal gases downloaded at 0.5 hz. Post-operatively, the presence of POD and POD severity was comprehensively assessed using the Confusion Assessment Measure –Severity (CAM-S scoring instrument on days 0 (surgery through post-operative day 5, and patients were followed up at least 1 month post-operatively.Results: Six of 12 patients had no evidence of POD (non-POD. Three patients had POD and 3 had clinically significant confusional states (referred as subthreshold POD; ST-POD (score ≥ 5/19 on the CAM-S. Average severity for delirium was 1.3 in the non-POD group, 3.2 in ST-POD, and 6.1 in POD (F-statistic = 15.4, p < 0.001. Depressive symptoms, and cognitive measures of semantic fluency and executive functioning/processing speed were significantly associated with POD. Second level analysis revealed an increased inverse BOLD responsiveness to CO2 pre-operatively in ST-POD and marked increase in the POD groups when compared to the non-POD group. An association was also noted for

  17. Intra-operative maternal complications of emergency cesarean section done in advanced labor

    International Nuclear Information System (INIS)

    Nisa, M.U.

    2013-01-01

    Background: Emergency cesarean section done in advanced labor is a big challenge in obstetrics due to increased risk of intraoperative complications. In the last decade, a rapid increase in cesarean section done in advanced labor has been observed. Difficult deli-very of the fetal head during cesarean section carries a high risk of intraoperative complications like cervical and uterine tears, intra operative hemorrhage and trauma to the baby. Objectives: The purpose of this study is to find out the frequency and risk factors for intra-operative complications in emergency cesarean section done in advanced labor, so that appropriate management protocols can be planned to reduce these complications. Study Design: Prospective cohort study. Materials and Methods: This prospective study was carried out in Obstetrics and Gynecology Unit - 2 of Services Institute of Medical Sciences, Services Hospital, Lahore; from 1st January 2007 to 31st December 2007. All patients undergoing emergency cesarean sections done on laboring mothers were included in the study. The sample was divided into two groups; emergency C-section done in advanced labor as the study group and emergency C-section in early labor as the control group. Data were collected regarding age, parity, booked or unbooked status, indications for cesarean section, level of competence of operating surgeon, intra-operative complications and the risk factors for these complications. Data were recorded on a structured proforma and compared between the two groups. Statistical Analysis: Data were analyzed using computer programme SPSS Version 14 for windows applying student t-test for quantitative and chai square test for qualitative parameters. A p-value < 0.05 was used as statistically significant. Results: Out of 2064 total deliveries in the year 2007, 1290 (62.5%) were vaginal deliveries and 774 (37.5%) were C-Sections. Out of 774 C-Section, 174 (23%) were elective and 600 (77%) were emergency. Out of 600 emergency C

  18. Achieving Adequate Margins in Ameloblastoma Resection: The Role for Intra-Operative Specimen Imaging. Clinical Report and Systematic Review

    Science.gov (United States)

    Ramakrishnan, Anand; Mirkazemi, Mansoor; Baillieu, Charles; Ptasznik, Ronnie; Leong, James

    2012-01-01

    Background Ameloblastoma is a locally aggressive odontogenic neoplasm. With local recurrence rates reaching 90%, only completeness of excision can facilitate cure. Surgical clearance has widely been based on pre-operative imaging to guide operative excision margins, however use of intra-operative specimen x-ray or frozen-section has been sought to improve clearance rates, and advanced imaging technologies in this role have been proposed. This manuscript aims to quantify the evidence for evaluating intra-operative resection margins and present the current standard in this role. Method The current study comprises the first reported comparison of imaging modalities for assessing ameloblastoma margins. A case is presented in which margins are assessed with each of clinical assessment based on preoperative imaging, intra-operative specimen x-ray, intra-operative specimen computed tomography (CT) and definitive histology. Each modality is compared quantitatively. These results are compared to the literature through means of systematic review of current evidence. Results A comparative study highlights the role for CT imaging over plain radiography. With no other comparative studies and a paucity of high level evidence establishing a role for intra-operative margin assessment in ameloblastoma in the literature, only level 4 evidence supporting the use of frozen section and specimen x-ray, and only one level 4 study assesses intra-operative CT. Conclusion The current study suggests that intra-operative specimen CT offers an improvement over existing techniques in this role. While establishing a gold-standard will require higher level comparative studies, the use of intra-operative CT can facilitate accurate single-stage resection. PMID:23094099

  19. Achieving adequate margins in ameloblastoma resection: the role for intra-operative specimen imaging. Clinical report and systematic review.

    Directory of Open Access Journals (Sweden)

    Inoka De Silva

    Full Text Available BACKGROUND: Ameloblastoma is a locally aggressive odontogenic neoplasm. With local recurrence rates reaching 90%, only completeness of excision can facilitate cure. Surgical clearance has widely been based on pre-operative imaging to guide operative excision margins, however use of intra-operative specimen x-ray or frozen-section has been sought to improve clearance rates, and advanced imaging technologies in this role have been proposed. This manuscript aims to quantify the evidence for evaluating intra-operative resection margins and present the current standard in this role. METHOD: The current study comprises the first reported comparison of imaging modalities for assessing ameloblastoma margins. A case is presented in which margins are assessed with each of clinical assessment based on preoperative imaging, intra-operative specimen x-ray, intra-operative specimen computed tomography (CT and definitive histology. Each modality is compared quantitatively. These results are compared to the literature through means of systematic review of current evidence. RESULTS: A comparative study highlights the role for CT imaging over plain radiography. With no other comparative studies and a paucity of high level evidence establishing a role for intra-operative margin assessment in ameloblastoma in the literature, only level 4 evidence supporting the use of frozen section and specimen x-ray, and only one level 4 study assesses intra-operative CT. CONCLUSION: The current study suggests that intra-operative specimen CT offers an improvement over existing techniques in this role. While establishing a gold-standard will require higher level comparative studies, the use of intra-operative CT can facilitate accurate single-stage resection.

  20. Reducing radiation exposure with iterative reconstruction: an inter- and intra-scanner analysis.

    Science.gov (United States)

    Rohr, Aaron; Wick, Jo; Hill, Jacqueline; Walter, Carissa; Irani, Neville; Best, Shaun; Miller, Kirk; Ash, Ryan

    2017-01-01

    Our purpose in this study was to compare delivered radiation exposure via computed tomography dose index volume (CTDI vol ) and dose length production (DLP) measurements from computed tomography (CT) examinations performed on scanners with and without image-quality enhancing iterative reconstruction (IR) software. A retrospective analysis was conducted on randomly selected chest, abdomen, and/or pelvis CT examinations from three different scanners from 1 January 2013 to 31 December 2013. CTDI vol and DLP measurements were obtained from two CT scanners with and one CT scanner without IR software. To evaluate inter-scanner variability, we compared measurements from the same model CT scanners, one with and one without IR software. To evaluate intra-scanner variability, we compared measurements between two scanners with IR software from different manufacturers. CT scanners with IR software aided in the overall reduction in radiation exposure, measured as CTDI vol by 30% and DLP by 39% when compared to a scanner without IR. There was no significant difference in CTDl vol or DLP measurements across different manufacturers with IR software. As a result, IR software significantly decreased the radiation exposure to patients, but there were no differences in radiation measurements across CT manufacturers with IR software.

  1. Intra-operative neurophysiological mapping and monitoring during brain tumour surgery in children: an update.

    Science.gov (United States)

    Coppola, Angela; Tramontano, Vincenzo; Basaldella, Federica; Arcaro, Chiara; Squintani, Giovanna; Sala, Francesco

    2016-10-01

    Over the past decade, the reluctance to operate in eloquent brain areas has been reconsidered in the light of the advent of new peri-operative functional neuroimaging techniques and new evidence from neuro-oncology. To maximise tumour resection while minimising morbidity should be the goal of brain surgery in children as much as it is in adults, and preservation of brain functions is critical in the light of the increased survival and the expectations in terms of quality of life. Intra-operative neurophysiology is the gold standard to localise and preserve brain functions during surgery and is increasingly used in paediatric neurosurgery. Yet, the developing nervous system has peculiar characteristics in terms of anatomical and physiological maturation, and some technical aspects need to be tailored for its use in children, especially in infants. This paper will review the most recent advances in the field of intra-operative neurophysiology (ION) techniques during brain surgery, focussing on those aspects that are relevant to the paediatric neurosurgery practice.

  2. The impact of intra-operative interruptions on surgeons' perceived workload: an observational study in elective general and orthopedic surgery.

    Science.gov (United States)

    Weigl, Matthias; Antoniadis, Sophia; Chiapponi, Costanza; Bruns, Christiane; Sevdalis, Nick

    2015-01-01

    Surgeons' intra-operative workload is critical for effective and safe surgical performance. Detrimental conditions in the operating room (OR) environment may add to perceived workload and jeopardize surgical performance and outcomes. This study aims to evaluate the impact of different intra-operative workflow interruptions on surgeons' capacity to manage their workload safely and efficiently. This was an observational study of intra-operative interruptions and self-rated workload in two surgical specialties (general, orthopedic/trauma surgery). Intra-operative interruptions were assessed via expert observation using a well-validated observation tool. Surgeons, nurses, and anesthesiologists assessed their intra-operative workload directly after case completion based on three items of the validated Surgery Task Load Index (mental demand, situational stress, distraction). A total of 56 elective cases (35 open, 21 laparoscopic) with 94 workload ratings were included. Mean intra-operative duration was 1 h 37 min. Intra-operative interruptions were on average observed 9.78 times per hour. People who entered/exited the OR (30.6 %) as well as telephone-/beeper-related disruptions (23.6 %) occurred most often. Equipment and OR environment-related interruptions were associated with highest interference with team functioning particularly in laparoscopic procedures. After identifying task and procedural influences, partial correlational analyses revealed that case-irrelevant communications were negatively associated with surgeons' mental fatigue and situational stress, whereas surgeons' reported distraction was increased by case-irrelevant communication and procedural disruptions. OR nurses' and anesthesiologists' perceived workload was also related to intra-operative interruption events. Our study documents the unique contribution of different interruptions on surgeons' workload; whereas case-irrelevant communications may be beneficial for mental fatigue and stress in routine

  3. Operative treatment of intra-articular calcaneal fractures with calcaneal plates and its complications

    Directory of Open Access Journals (Sweden)

    Rak Vaclav

    2009-01-01

    Full Text Available Background: In a retrospective study we analysed intra-articular calcaneal fracture treatment by comparing results and complications related to fracture stabilization with nonlocking calcaneal plates and locking compression plates. Materials and Methods: We performed 76 osteosynthesis (67 patients of intra-articular calcaneal fractures using the standard extended lateral approach from February 2004 to October 2007. Forty-two operations using nonlocking calcaneal plates (group A were performed during the first three years, and 34 calcaneal fractures were stabilized using locking compression plates (group B in 2007. In the Sanders type IV fractures, reconstruction of the calcaneal shape was attempted. Depending on the type of late complication, we performed subtalar arthroscopy in six cases, arthroscopically assisted subtalar distraction bone block arthrodesis in six cases, and plate removal with lateral-wall decompression in five cases. The patients were evaluated by the AOFAS Ankle-Hindfoot Scale. Results: Wound healing complications were 7/42 (17% in group A and 1/34 (3% in group B. No patient had deep osseous infection or foot rebound compartment syndrome. Preoperative size of Bφhler´s angle correlated with postoperative clinical results in both groups. There were no late complications necessitating corrective procedure or arthroscopy until December 2008 in Group B. All late complications ccurred in Group A. The overall results according to the AOFAS Ankle Hindfoot Scale were good or excellent in 23/42 (55% in group A and in 30/34 (85% in group B. Conclusion: Open reduction and internal fixation of intra-articular calcaneal fractures has become a standard surgical method. Fewer complications and better results related to treatment with locking compression plates confirmed in comparison to nonlocking ones were noted for all Sanders types of intra-articular calcaneal fractures. Age and Sanders type IV fractures are not considered to be the

  4. Inter- and intra-observer agreement of the AO classification for operatively treated distal radius fractures.

    Science.gov (United States)

    van Buijtenen, Jesse M; van Tunen, Mischa L C; Zuidema, Wietse P; Heilbron, Emile A; de Haan, Jeroen; de Vet, Henrica C W; Derksen, Robert J

    2015-11-01

    The reproducibility of the AO classification for distal radius fractures remains a topic of debate. Previous studies showed variable reproducibility results. Important treatment decisions depend on correct classification, especially in comminuted, intra-articular fractures. Therefore, reliable reproducibility results need to be undisputedly determined. Hence, the study objective was to assess inter- and intra-observer agreement of the AO classification for operatively treated distal radius fractures. A database of 54 radiographs of all AO types (A, B and C) and groups (A2-3, B1-3, and C1-3) of distal radius fractures was assessed in twofold. Likewise, a subset of 152 radiographs of solely C-type groups (C1-3) was assessed. All fractures were classified by six observers with different experience levels: three consultant trauma surgeons, one sixth-year trauma surgery resident, a consultant trauma radiologist, and an intern with limited experienced. The inter-observer agreement of both main types and groups was moderate (κ = 0.49 resp. κ = 0.48) in combination with a good intra-observer agreement (κ = 0.68 resp. κ = 0.70). The inter-observer agreement of the subset C-type fractures group was fair (κ = 0.27) with moderate intra-observer agreement (κ = 0.43). According to these results, the reproducibility of the AO classification of main types and groups of distal radius fractures based on conventional radiographs is insufficient (κ < 0.50), especially at group level of C-type fractures.

  5. Impact of intra-operative intraperitoneal chemotherapy on organ/space surgical site infection in patients with gastric cancer.

    Science.gov (United States)

    Liu, X; Duan, X; Xu, J; Jin, Q; Chen, F; Wang, P; Yang, Y; Tang, X

    2015-11-01

    Various risk factors for surgical site infection (SSI) have been identified such as age, overweight, duration of surgery, blood loss, etc. Intraperitoneal chemotherapy during surgery is a common procedure in patients with gastric cancer, yet its impact on SSI has not been evaluated. To evaluate whether intra-operative intraperitoneal chemotherapy is a key risk factor for organ/space SSI in patients with gastric cancer. All patients with gastric cancer who underwent surgery at the Department of Gastrointestinal Surgery between January 2008 and December 2013 were studied. The organ/space SSI rates were compared between patients who received intra-operative intraperitoneal chemotherapy and patients who did not receive intra-operative intraperitoneal chemotherapy, and the risk factors for organ/space SSI were analysed by univariate and multi-variate regression analyses. The microbial causes of organ/space SSI were also identified. Of the eligible 845 patients, 356 received intra-operative intraperitoneal chemotherapy, and the organ/space SSI rate was higher in these patients compared with patients who did not receive intra-operative intraperitoneal chemotherapy (9.01% vs 3.88%; P = 0.002). Univariate analysis confirmed the significance of this finding (odds ratio 2.443; P = 0.003). As a result, hospital stay was increased in patients who received intra-operative intraperitoneal chemotherapy {mean 20.91 days [95% confidence interval (CI) 19.76-22.06] vs 29.72 days (95% CI 25.46-33.99); P = 0.000}. The results also suggested that intra-operative intraperitoneal chemotherapy may be associated with more Gram-negative bacterial infections. Intra-operative intraperitoneal chemotherapy is a significant risk factor for organ/space SSI in patients with gastric cancer. Copyright © 2015 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

  6. Intra-operative 3-T MRI for paediatric brain tumours: challenges and perspectives

    International Nuclear Information System (INIS)

    Abernethy, L.J.; Avula, S.; Hughes, G.M.; Wright, E.J.; Mallucci, C.L.

    2012-01-01

    MRI is the ideal modality for imaging intracranial tumours. Intraoperative MRI (ioMRI) makes it possible to obtain scans during a neurosurgical operation that can aid complete macroscopic tumour resection - a major prognostic factor in the majority of brain tumours in children. Intra-operative MRI can also help limit damage to normal brain tissue. It therefore has the potential to improve the survival of children with brain tumours and to minimise morbidity, including neurological deficits. The use of ioMRI is also likely to reduce the need for second look surgery, and may reduce the need for chemotherapy and radiotherapy. High-field MRI systems provide better anatomical information and also enable effective utilisation of advanced MRI techniques such as perfusion imaging, diffusion tensor imaging, and magnetic resonance spectroscopy. However, high-field ioMRI facilities require substantial capital investment, and careful planning is required for optimal benefit. Safe ioMRI requires meticulous attention to detail and rigorous application of magnetic field safety precautions. Interpretation of ioMRI can be challenging and requires experience and understanding of artefacts that are common in the intra-operative setting. (orig.)

  7. In vivo intra-operative breast tumor margin detection using a portable OCT system with a handheld surgical imaging probe

    Science.gov (United States)

    Erickson-Bhatt, Sarah J.; Nolan, Ryan; Shemonski, Nathan D.; Adie, Steven G.; Putney, Jeffrey; Darga, Donald; McCormick, Daniel T.; Cittadine, Andrew; Marjanovic, Marina; Chaney, Eric J.; Monroy, Guillermo L.; South, Fredrick; Carney, P. Scott; Cradock, Kimberly A.; Liu, Z. George; Ray, Partha S.; Boppart, Stephen A.

    2014-02-01

    Breast-conserving surgery is a frequent option for women with stage I and II breast cancer, and with radiation treatment, can be as effective as a mastectomy. However, adequate margin detection remains a challenge, and too often additional surgeries are required. Optical coherence tomography (OCT) provides a potential method for real-time, high-resolution imaging of breast tissue during surgery. Intra-operative OCT imaging of excised breast tissues has been previously demonstrated by several groups. In this study, a novel handheld surgical probe-based OCT system is introduced, which was used by the surgeon to image in vivo, within the tumor cavity, and immediately following tumor removal in order to detect the presence of any remaining cancer. Following resection, study investigators imaged the excised tissue with the same probe for comparison. We present OCT images obtained from over 15 patients during lumpectomy and mastectomy surgeries. Images were compared to post-operative histopathology for diagnosis. OCT images with micron scale resolution show areas of heterogeneity and disorganized features indicative of malignancy, compared to more uniform regions of normal tissue. Video-rate acquisition shows the inside of the tumor cavity as the surgeon sweeps the probe along the walls of the surgical cavity. This demonstrates the potential of OCT for real-time assessment of surgical tumor margins and for reducing the unacceptably high re-operation rate for breast cancer patients.

  8. SU-F-T-80: A Mobile Application for Intra-Operative Electron Radiotherapy Treatment Planning

    International Nuclear Information System (INIS)

    Williams, C; Crowley, E; Wolfgang, J

    2016-01-01

    Purpose: Intraoperative electron radiotherapy (IORT) poses a unique set of challenges for treatment planning. Planning must be performed in a busy operating room environment over a short timeframe often with little advance knowledge of the treatment depth or applicator size. Furthermore, IORT accelerators can have a large number of possible applicators, requiring extensive databooks that must be searched for the appropriate dosimetric parameters. The goal of this work is to develop a software tool to assist in the planning process that is suited to the challenges faced in the IORT environment. Methods: We developed a mobile application using HTML5 and Javascript that can be deployed to tablet devices suitable for use in the operating room. The user selects the desired treatment parameters cone diameter, bevel angle, and energy (a total of 141 datasets) and desired bolus. The application generates an interactive display that allows the user to dynamically select points on the depth-dose curve and to visualize the shape of the corresponding isodose contours. The user can indicate a prescription isodose line or depth. The software performs a monitor unit calculation and generates a PDF report. Results: We present our application, which is now used routinely in our IORT practice. It has been employed successfully in over 23 cases. The interactivity of the isodose distributions was found to be of particular use to physicians who are less-frequent IORT users, as well as for the education of residents and trainees. Conclusion: This software has served as a useful tool in IORT planning, and demonstrates the need for treatment planning tools that are designed for the specialized challenges encountered in IORT. This software is the subject of a license agreement with the IntraOp Medical Corporation. This software is the subject of a license agreement between Massachusetts General Hospital / Partners Healthcare and the IntraOp Medical Corporation. CLW is consulting on

  9. SU-F-T-80: A Mobile Application for Intra-Operative Electron Radiotherapy Treatment Planning

    Energy Technology Data Exchange (ETDEWEB)

    Williams, C [Brigham and Women’s Hospital & Dana Farber Cancer Institute, Boston, MA (United States); Harvard Medical School, Boston, MA (United States); Crowley, E; Wolfgang, J [Harvard Medical School, Boston, MA (United States); Massachusetts General Hospital, Boston, MA (United States)

    2016-06-15

    Purpose: Intraoperative electron radiotherapy (IORT) poses a unique set of challenges for treatment planning. Planning must be performed in a busy operating room environment over a short timeframe often with little advance knowledge of the treatment depth or applicator size. Furthermore, IORT accelerators can have a large number of possible applicators, requiring extensive databooks that must be searched for the appropriate dosimetric parameters. The goal of this work is to develop a software tool to assist in the planning process that is suited to the challenges faced in the IORT environment. Methods: We developed a mobile application using HTML5 and Javascript that can be deployed to tablet devices suitable for use in the operating room. The user selects the desired treatment parameters cone diameter, bevel angle, and energy (a total of 141 datasets) and desired bolus. The application generates an interactive display that allows the user to dynamically select points on the depth-dose curve and to visualize the shape of the corresponding isodose contours. The user can indicate a prescription isodose line or depth. The software performs a monitor unit calculation and generates a PDF report. Results: We present our application, which is now used routinely in our IORT practice. It has been employed successfully in over 23 cases. The interactivity of the isodose distributions was found to be of particular use to physicians who are less-frequent IORT users, as well as for the education of residents and trainees. Conclusion: This software has served as a useful tool in IORT planning, and demonstrates the need for treatment planning tools that are designed for the specialized challenges encountered in IORT. This software is the subject of a license agreement with the IntraOp Medical Corporation. This software is the subject of a license agreement between Massachusetts General Hospital / Partners Healthcare and the IntraOp Medical Corporation. CLW is consulting on

  10. A standardized and safe method of sterile field maintenance during intra-operative horizontal plane fluoroscopy

    Directory of Open Access Journals (Sweden)

    Kaska Serge C

    2010-12-01

    Full Text Available Abstract Background Intra-operative fluoroscopy for orthopaedic procedures frequently involves imaging in the horizontal plane, which requires the lower portion of the C-arm (x-ray tube to be rotated from an unsterile zone (beneath the table into the sterile field. To protect the integrity of the sterile field the C-arm must be draped repeatedly throughout the surgical case. The current, un-standardized, practice employs draping procedures which violate the Association of peri-Operative Registered Nurses (AORN Standards and Recommended Practices, waste time and material, and pose an increased risk for surgical site infection. Presentation of the hypothesis Use of a novel sterile C-arm drape (C-armor that maintains the integrity of the sterile field, will improve operating room efficiency and reduce surgical site infection risk factors. This reduction in risk factors may potentially reduce surgical site infections in orthopaedic surgical cases requiring repeated horizontal x-ray imaging. Testing the Hypothesis Savings in time and material and the reduction in surgical site infection risk factors afforded by using C-armor are intuitive to those skilled in the practice of orthopaedic surgery. Testing for a reduction in the number of microorganisms introduced to the surgical site by improved C-arm draping would be challenging due to the multiple confounding factors during a surgical operation. Determination of an absolute reduction in surgical site infections may be possible, but will require accounting for many confounding variables and a large study sample in order to achieve statistical significance. Implications of the Hypothesis Improved intraoperative workflow, healthcare savings and a reduction in surgical site infection risk factors will be achieved by utilizing a standardized and safe method of sterile field maintenance during intra-operative horizontal plane fluoroscopy.

  11. Minimizing shoulder syndrome with intra-operative spinal accessory nerve monitoring for neck dissection.

    Science.gov (United States)

    Lee, C-H; Huang, N-C; Chen, H-C; Chen, M-K

    2013-04-01

    The objective of this study was to analyze the safety and results of intra-operative SAN (spinal accessary nerve) monitoring during selective neck dissection, with emphasis on shoulder syndrome. Twenty-five consecutive patients with head and neck cancer were studied. Selective neck dissection was performed by a single clinical fellow under the supervision of the department chief using an intra-operative SAN monitor. Electrophysiological data were recorded after initial identification of the SAN and continued until just before closure. Electromyographic evaluation was carried out to assess SAN function one month postoperatively. Shoulder disability was also evaluated at this time using a questionnaire for shoulder syndrome (shrug, flexion, abduction, winging, and pain). No patients had postoperative shoulder syndrome involving shrug, flexion, abduction, or winging. Twenty-two of the 25 (88%) patients had shoulder pain, but the average pain score was low (2.3 ± 1.3). No patients had neck recurrence during at least 1 year of follow up. By using nerve monitoring during selective neck dissection, no patient developed significant "shoulder syndrome", with the exception of slight pain.

  12. The effect of intra-operative transcutaneous electrical nerve stimulation on posterior neck pain following thyroidectomy.

    Science.gov (United States)

    Park, C; Choi, J B; Lee, Y-S; Chang, H-S; Shin, C S; Kim, S; Han, D W

    2015-04-01

    Posterior neck pain following thyroidectomy is common because full neck extension is required during the procedure. We evaluated the effect of intra-operative transcutaneous electrical nerve stimulation on postoperative neck pain in patients undergoing total thyroidectomy under general anaesthesia. One hundred patients were randomly assigned to one of two groups; 50 patients received transcutaneous electrical nerve stimulation applied to the trapezius muscle and 50 patients acted as controls. Postoperative posterior neck pain and anterior wound pain were evaluated using an 11-point numerical rating scale at 30 min, 6 h, 24 h and 48 h following surgery. The numerical rating scale for posterior neck pain was significantly lower in the transcutaneous electrical nerve stimulation group compared with the control group at all time points (p < 0.05). There were no significant differences in the numerical rating scale for anterior wound pain at any time point. No adverse effects related to transcutaneous electrical nerve stimulation were observed. We conclude that intra-operative transcutaneous electrical nerve stimulation applied to the trapezius muscle reduced posterior neck pain following thyroidectomy. © 2014 The Association of Anaesthetists of Great Britain and Ireland.

  13. Evaluation of intra- and inter-fraction movement of the cervix during intensity modulated radiation therapy

    International Nuclear Information System (INIS)

    Haripotepornkul, Nora H.; Nath, Sameer K.; Scanderbeg, Daniel; Saenz, Cheryl; Yashar, Catheryn M.

    2011-01-01

    Background and purpose: To assess the degree of intra- and inter-fraction cervical motion throughout a course of intensity modulated radiation therapy (IMRT) for cervical cancer patients. Materials and methods: A retrospective study of 10 women with stage 1B1-3B cervical cancer diagnosed from September 2007 to July 2008 was conducted. All patients were treated with chemoradiation using IMRT followed by intracavitary brachytherapy. Pretreatment, patients had 2 seeds placed at a depth of 10 mm into the cervix. On-Board Imaging (OBI) was used to obtain anterior/posterior (AP) and lateral X-rays before and after each treatment. OBI images were rigidly aligned to baseline digitally reconstructed radiographs (DRRs), and movement of cervical seeds was determined in the lateral, vertical, and AP directions. Mean differences in cervical seed position and standard error of the mean (SEM) were calculated. Results: A total of 922 images were reviewed, with approximately 90 images per patient. The mean intra-fractional movement in cervical seed position in the lateral, vertical, and AP directions were 1.6 mm (SD ± 2.0), 2.6 mm (SD ± 2.4), and 2.9 mm (SD ± 2.7), respectively, with a range from 0 to 15 mm for each direction. The mean inter-fractional movement in the lateral, vertical, and AP directions were 1.9 mm (SD ± 1.9), 4.1 mm (SD ± 3.2), and 4.2 mm (SD ± 3.5), respectively, with a range from 0 to 18 mm for each direction. Conclusions: This is the first study to assess intra- and inter-fractional movement of the cervix using daily imaging before and after each fraction. Within and between radiation treatments, cervical motion averages approximately 3 mm in any given direction. However, maximal movement of the cervix can be as far as 18 mm from baseline. This wide range of motion needs to be accounted for when generating planning treatment volumes.

  14. Diagnosis of pelvic inflammatory disease (PID): intra-operative findings and comparison of vaginal and intra-abdominal cultures.

    Science.gov (United States)

    Schindlbeck, Christian; Dziura, Dominik; Mylonas, Ioannis

    2014-06-01

    Pelvic inflammatory disease (PID) is frequent in adolescents and younger women. Diagnosis is usually based on the clinical findings, and the threshold for empiric antibiotic therapy should be low. However, at least in cases of resistance toward therapy or deterioration of symptoms, laparoscopic evaluation can be helpful. We searched the hospital charts for in-house patients who were treated for PID or tubo-ovarian abscess between 2007 and 2010. In cases with both vaginal and intra-abdominal bacterial cultures, results of those were compared. 73 patients with suspected PID or tubo-ovarian abscess were included. Median patients' age was 40 years (18-88), 18 of 73 (24.7 %) patients had an IUD at the time of consultation. 58 patients underwent laparoscopy or laparotomy. In 41 patients (70.7 %) tubo-ovarian abscess could be confirmed, four patients had differential gynecologic diagnoses, and two patients appendicitis. In vaginal swabs, most frequent bacteria were Streptococcus sp. (28.5 %), Escherichia coli (22.2 %), Enterococcus faecalis (15.9 %), and Staphylococcus sp. (9.5 %). In eight patients (11 %) Chlamydia trachomatis could be found, there was no case of Neisseria gonorrhea. In 33 patients both vaginal and abdominal cultures were available. In nine cases (27.3 %), identical bacteria could be found, however, 11 cases (33.3 %) showed different results. In severe cases of PID, laparoscopic evaluation and taking an intra-abdominal bacterial culture are helpful for the confirmation of diagnosis, accurate microbiologic testing and specific therapy.

  15. An evaluation of intra-operative and post-operative blood loss in ...

    African Journals Online (AJOL)

    Background: Total knee replacement is a rewarding and reliable procedure, producing a lasting relief to severe knee pains. However, significant blood loss usually in the post-operative period may be a challenge, necessitating prompt restoration of circulating blood volume to minimize morbidity and mortality. The aim of this ...

  16. Intra-operative Ultrasound as a Tool to Assess Free Borders of Primary Vascular Aortic Tumors During Resection

    Directory of Open Access Journals (Sweden)

    R.M. Andersen

    Full Text Available : Introduction: Primary vascular tumors are rare and, in general, have a poor prognosis. Complete resection is associated with a better prognosis. Radical resection depends on safe discrimination of tumor borders. Technical summary: A 54 year old woman presented with abdominal pain. Imaging revealed a mass in the thoracic aorta, highly suspicious of angiosarcoma which was confirmed post-operatively by histological analysis. Open surgery was performed. Prior to clamping of the aorta, intra-operative ultrasound established clear delineation of the tumor borders. Conclusion: Intra-operative ultrasound was, in this case, a safe and easy method to determine the tumor borders, providing a simple guide to in toto tumor removal. Keywords: Angiosarcoma, Intra-operative ultrasound, In toto tumor removal, Fludeoxyglucose positron emission tomography/computed tomography, Magnetic resonance imaging

  17. Intra-operator and inter-operator reliability of manual and semiautomated measurement of fetal nuchal translucency : a cross sectional study

    NARCIS (Netherlands)

    Bakker, M.; Mulder, P.; Birnie, E.; Bilardo, C. M.

    2013-01-01

    ObjectiveThe goal of this study was to examine the intra-operator and inter-operator differences of the manual and semiautomated nuchal translucency (NT) measurements and to evaluate if these differences alter women's risk status. MethodsA cross sectional study was performed. Two operators obtained

  18. l-Arginine Pathway Metabolites Predict Need for Intra-operative Shunt During Carotid Endarterectomy.

    Science.gov (United States)

    Szabo, P; Lantos, J; Nagy, L; Keki, S; Volgyi, E; Menyhei, G; Illes, Z; Molnar, T

    2016-12-01

    Asymmetric dimethylarginine (ADMA) inhibits nitric oxide (NO) synthesis and is a marker of atherosclerosis. This study examined the correlation between pre-operative l-arginine and ADMA concentration during carotid endarterectomy (CEA), and jugular lactate indicating anaerobic cerebral metabolism, jugular S100B reflecting blood-brain barrier integrity, and with factors of surgical intervention. The concentration of l-arginine, ADMA, and symmetric dimethylarginine was measured in blood taken under regional anaesthesia from the radial artery of 55 patients prior to CEA. Blood gas parameters, concentration of lactate, and S100B were also serially measured in blood taken from both the radial artery and the jugular bulb before and after carotid clamping, and after release of the clamp. To estimate anaerobic metabolism, the jugulo-arterial ratio of CO 2 gap/oxygen extraction was calculated. Positive correlation was found between pre-operative ADMA levels and the ratio of jugulo-arterial CO 2 gap/oxygen extraction during clamp and reperfusion (p = .005 and p = .01, respectively). An inverse correlation was found between the pre-operative l-arginine concentration and jugular lactate at each time point (both p = .002). The critical pre-operative level of l-arginine was determined by receiver operator curve analysis. If l-arginine was below the cutoff value of 35 μmol/L, jugular S100B concentration was higher 24 h post-operatively (p = .03), and jugular lactate levels were increased during reperfusion (p = .02). The median pre-operative concentration of l-arginine was lower in patients requiring an intra-operative shunt than in patients without need of shunt (median: 30.3 μmol/L [interquartile range 24.4-34.4 μmol/L] vs. 57.6 μmol/L [interquartile range 42.3-74.5 μmol/L]; p = .002). High pre-operative ADMA concentration predicts poor cerebral perfusion indicated by elevated jugulo-arterial CO 2 gap/oxygen extraction. Low pre-operative l

  19. Operative treatment of radiation-induced fistulae

    International Nuclear Information System (INIS)

    Balslev, I.; Harling, H.

    1987-01-01

    Out of 136 patients with radiation-induced intestinal complications, 45 had fistulae. Twenty-eight patients had rectovaginal fistulae while the remainder had a total of 13 different types of fistulae. Thirty-seven patients were treated operatively and eight were treated conservatively. Thirty-three patients were submitted to operation for rectal fistulae. Of these, 28 were treated by defunctioning colostomy, three were treated by Hartmann's method and resection and primary anastomosis was carried out in two patients. In the course of the period of observation, 35% of the patients developed new radiation damage. The frequency in the basic material without fistulae was 21% (0.05< p<0.10). Following establishment of defunctioning colostomy on account of rectovaginal fistulae in 25 patients, eight patients developed new fistulae, Significantly more patients with fistulae died of recurrence as compared with patients with other lesions (p<0.01). Defunctioning colostomy in the treatment of rectal fistula is a reasonable form of treatment in elderly patients and in case of recurrence. Younger patients should be assessed in a special department in view of the possibility of a sphincter-preserving procedure following resection of the rectum and restorative anastomosis. (author)

  20. Operative treatment of radiation-induced fistulae

    Energy Technology Data Exchange (ETDEWEB)

    Balslev, I.; Harling, H.

    1987-01-01

    Out of 136 patients with radiation-induced intestinal complications, 45 had fistulae. Twenty-eight patients had rectovaginal fistulae while the remainder had a total of 13 different types of fistulae. Thirty-seven patients were treated operatively and eight were treated conservatively. Thirty-three patients were submitted to operation for rectal fistulae. Of these, 28 were treated by defunctioning colostomy, three were treated by Hartmann's method and resection and primary anastomosis was carried out in two patients. In the course of the period of observation, 35% of the patients developed new radiation damage. The frequency in the basic material without fistulae was 21% (0.05

  1. Observation of behavioural markers of non-technical skills in the operating room and their relationship to intra-operative incidents.

    Science.gov (United States)

    Siu, Joey; Maran, Nikki; Paterson-Brown, Simon

    2016-06-01

    The importance of non-technical skills in improving surgical safety and performance is now well recognised. Better understanding is needed of the impact that non-technical skills of the multi-disciplinary theatre team have on intra-operative incidents in the operating room (OR) using structured theatre-based assessment. The interaction of non-technical skills that influence surgical safety of the OR team will be explored and made more transparent. Between May-August 2013, a range of procedures in general and vascular surgery in the Royal Infirmary of Edinburgh were performed. Non-technical skills behavioural markers and associated intra-operative incidents were recorded using established behavioural marking systems (NOTSS, ANTS and SPLINTS). Adherence to the surgical safety checklist was also observed. A total of 51 procedures were observed, with 90 recorded incidents - 57 of which were considered avoidable. Poor situational awareness was a common area for surgeons and anaesthetists leading to most intra-operative incidents. Poor communication and teamwork across the whole OR team had a generally large impact on intra-operative incidents. Leadership was shown to be an essential set of skills for the surgeons as demonstrated by the high correlation of poor leadership with intra-operative incidents. Team-working and management skills appeared to be especially important for anaesthetists in the recovery from an intra-operative incident. A significant number of avoidable incidents occur during operative procedures. These can all be linked to failures in non-technical skills. Better training of both individual and team in non-technical skills is needed in order to improve patient safety in the operating room. Copyright © 2014 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.

  2. Using the transverse acetabular ligament as a landmark for acetabular anteversion: an intra-operative measurement.

    Science.gov (United States)

    Inoue, Masahiro; Majima, Tokifumi; Abe, Satomi; Nakamura, Takayuki; Kanno, Taiki; Masuda, Takeshi; Minami, Akio

    2013-08-01

    PURPOSE. To measure the transverse acetabular ligament (TAL) anteversion in hips with severe deformity, using fluoroscopy-computed tomographic navigation. METHODS. 31 hips in 10 men and 19 women aged 40 to 78 (mean, 58.7) years who underwent total hip arthroplasty for primary osteoarthritis (n=6) or osteoarthritis secondary to developmental hip dysplasia (n=19) or congenital hip dislocation (n=6) were included. The severity of hip dislocation was classified according to the Crowe classification; 15 hips were grade 1, 7 were grade 2, 3 were grade 3, and 6 were grade 4. The TAL anteversion was measured using fluoroscopy-computed tomographic navigation. The difference in TAL anteversion between non-dislocated hips (Crowe grade 1, n=15) and dislocated hips (Crowe grades 2-4, n=16) was compared. RESULTS. In all 31 hips, the TAL could be visualised intra-operatively. No patient reported severe pain, early wear, loosening, or dislocation after 2 years. The mean TAL anteversion and inclination angles measured by the navigation system were 26.5 (SD, 8.9; range, 8-42) degrees and 41.5 (SD, 4.6; range, 32-49) degrees, respectively. 22 of the 31 hips were in the safe zone. TAL anteversion in non-dislocated and dislocated hips was not significantly different. Inter- and intra-observer mean absolute differences in TAL anteversion were 0.3 and 0.4 degree, respectively. CONCLUSION. The TAL is a useful anatomic landmark for total hip arthroplasty in dislocated hips.

  3. Intra-operative ultrasound-based augmented reality guidance for laparoscopic surgery.

    Science.gov (United States)

    Singla, Rohit; Edgcumbe, Philip; Pratt, Philip; Nguan, Christopher; Rohling, Robert

    2017-10-01

    In laparoscopic surgery, the surgeon must operate with a limited field of view and reduced depth perception. This makes spatial understanding of critical structures difficult, such as an endophytic tumour in a partial nephrectomy. Such tumours yield a high complication rate of 47%, and excising them increases the risk of cutting into the kidney's collecting system. To overcome these challenges, an augmented reality guidance system is proposed. Using intra-operative ultrasound, a single navigation aid, and surgical instrument tracking, four augmentations of guidance information are provided during tumour excision. Qualitative and quantitative system benefits are measured in simulated robot-assisted partial nephrectomies. Robot-to-camera calibration achieved a total registration error of 1.0 ± 0.4 mm while the total system error is 2.5 ± 0.5 mm. The system significantly reduced healthy tissue excised from an average (±standard deviation) of 30.6 ± 5.5 to 17.5 ± 2.4 cm 3 ( p < 0.05) and reduced the depth from the tumor underside to cut from an average (±standard deviation) of 10.2 ± 4.1 to 3.3 ± 2.3 mm ( p < 0.05). Further evaluation is required in vivo, but the system has promising potential to reduce the amount of healthy parenchymal tissue excised.

  4. Photo-acoustic imaging of blue nanoparticle targeted brain tumor for intra-operative glioma delineation

    Science.gov (United States)

    Ray, Aniruddha; Wang, Xueding; Koo Lee, Yong-Eun; Hah, HoeJin; Kim, Gwangseong; Chen, Thomas; Orrienger, Daniel; Sagher, Oren; Kopelman, Raoul

    2011-07-01

    Distinguishing the tumor from the background neo-plastic tissue is challenging for cancer surgery such as surgical resection of glioma. Attempts have been made to use visible or fluorescent markers to delineate the tumors during surgery. However, the systemic injection of the dyes requires high dose, resulting in negative side effects. A novel method to delineate rat brain tumors intra-operatively, as well as post-operatively, using a highly sensitive photoacoustic imaging technique enhanced by tumor targeting blue nanoparticle as contrast agent is demonstrated. The nanoparticles are made of polyacrylamide (PAA) matrix with covalently linked Coomassie-Blue dye. They contain 7.0% dye and the average size is 80nm. Their surface was conjugated with F3 peptide for active tumor targeting. These nanoparticles are nontoxic, chemically inert and have long plasma circulation lifetime, making them suitable as nanodevices for imaging using photoacoustics. Experiments on phantoms and rat brains tumors ex-vivo demonstrate the high sensitivity of photoacoustic imaging in delineating the tumor, containing contrast agent at concentrations too low to be visualized by eye. The control tumors without nanoparticles did not show any enhanced signal. This study shows that photoacoustic imaging facilitated with the nanoparticle contrast agent could contribute to future surgical procedures for glioma.

  5. Radiation absorbed from dental implant radiography: a comparison of linear tomography, CT scan, and panoramic and intra-oral techniques

    Energy Technology Data Exchange (ETDEWEB)

    Clark, D.E.; Danforth, R.A.; Barnes, R.W.; Burtch, M.L. (Loma Linda Univ., CA (USA))

    1990-01-01

    Absorbed radiation dose in bone marrow, thyroid, salivary gland, eye, and skin entrance was determined by placement of lithium fluoride thermoluminescent dosimeters (TLD's) at selected anatomical sites within and on a human-like x-ray phantom. The phantom was exposed to radiation from linear tomographic and computer-assisted tomographic (CT) simulated dental implant radiographic examinations. The mean dose was determined for each anatomical site. Resulting dose measurements from linear tomography and computer-assisted tomography are compared with reported panoramic and intra-oral doses. CT examination delivered the greatest dose, while linear tomography was generally lowest. Panoramic and intra-oral doses were similar to those of linear tomography.

  6. Radiation dose and intra-articular access: comparison of the lateral mortise and anterior midline approaches to fluoroscopically guided tibiotalar joint injections

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Ambrose J.; Torriani, Martin; Bredella, Miriam A.; Chang, Connie Y.; Simeone, Frank J.; Palmer, William E. [Massachusetts General Hospital, Department of Radiology, Division of Musculoskeletal Imaging and Intervention, Boston, MA (United States); Balza, Rene [Centro Medico de Occidente, Department of Radiology, Maracaibo (Venezuela, Bolivarian Republic of)

    2016-03-15

    To compare the lateral mortise and anterior midline approaches to fluoroscopically guided tibiotalar joint injections with respect to successful intra-articular needle placement, fluoroscopy time, radiation dose, and dose area product (DAP). This retrospective study was IRB-approved and HIPAA-compliant. 498 fluoroscopically guided tibiotalar joint injections were performed or supervised by one of nine staff radiologists from 11/1/2010-12/31/2013. The injection approach was determined by operator preference. Images were reviewed on a PACS workstation to determine the injection approach (lateral mortise versus anterior midline) and to confirm intra-articular needle placement. Fluoroscopy time (minutes), radiation dose (mGy), and DAP (μGy-m{sup 2}) were recorded and compared using the student's t-test (fluoroscopy time) or the Wilcoxon rank sum test (radiation dose and DAP). There were 246 lateral mortise injections and 252 anterior midline injections. Two lateral mortise injections were excluded from further analysis because no contrast was administered. Intra-articular location of the needle tip was documented in 242/244 lateral mortise injections and 252/252 anterior midline injections. Mean fluoroscopy time was shorter for the lateral mortise group than the anterior midline group (0.7 ± 0.5 min versus 1.2 ± 0.8 min, P < 0.0001). Mean radiation dose and DAP were less for the lateral mortise group than the anterior midline group (2.1 ± 3.7 mGy versus 2.5 ± 3.5 mGy, P = 0.04; 11.5 ± 15.3 μGy-m{sup 2} versus 13.5 ± 17.3 μGy-m{sup 2}, P = 0.006). Both injection approaches resulted in nearly 100 % rates of intra-articular needle placement, but the lateral mortise approach used approximately 40 % less fluoroscopy time and delivered 15 % lower radiation dose and DAP to the patient. (orig.)

  7. Operational experience of gamma radiation processing facility

    International Nuclear Information System (INIS)

    Patel, Nilesh

    2014-01-01

    Universal lSO-MED is now proud to announce an extension of its irradiation service for low-dose applications specifically in agriculture commodities, food and healthcare applications with the start of Gujarat Agro Radiation Processing Facility at Village: Bavla, Ahmedabad (A Government Enterprise) Operated, Maintained and Managed by Universal Medicap Ltd. Availability of hygienic, safe and nutritious food commodities is essential for any sustainable human development. Food stability is an important element of economic stability and self-reliance of a nation. Though the need to preserve food has been felt by the mankind since the time immemorial, it is even stronger in today's context. The rising population and increasing gap between demand and supply, agro-climatic conditions, in adequate post-harvest practices, seasonal nature of produce and long distances between production and consumption centers underscore the need to device improved conservation and preservation strategies

  8. Protecting Patients from an Unsafe System: The Etiology & Recovery of Intra-Operative Deviations in Care

    Science.gov (United States)

    Hu, Yue-Yung; Arriaga, Alexander F.; Roth, Emilie M.; Peyre, Sarah E.; Corso, Katherine A.; Swanson, Richard S.; Osteen, Robert T.; Schmitt, Pamela; Bader, Angela M.; Zinner, Michael J.; Greenberg, Caprice C.

    2012-01-01

    Objective To understand the etiology and resolution of unanticipated events in the operating room (OR). Background The majority of surgical adverse events occur intra-operatively. The OR represents a complex, high-risk system. The influence of different human, team, and organizational/environmental factors on safety and performance is unknown. Methods We video-recorded and transcribed 10 high-acuity operations, representing 43.7 hours of patient care. Deviations, defined as delays and/or episodes of decreased patient safety, were identified by majority consensus of a multidisciplinary team. Factors that contributed to each event and/or mitigated its impact were determined and attributed to the patient, providers, or environment/organization. Results Thirty-three deviations (10 delays, 17 safety compromises, 6 both) occurred – with a mean of one every 79.4 minutes. These deviations were multifactorial (mean 3.1 factors). Problems with communication and organizational structure appeared repeatedly at the root of both types of deviations. Delays tended to be resolved with vigilance, communication, coordination, and cooperation, while mediation of safety compromises was most frequently accomplished with vigilance, leadership, communication, and/or coordination. The organization/environment was not found to play a direct role in compensation. Conclusions Unanticipated events are common in the OR. Deviations result from poor organizational/environmental design and suboptimal team dynamics, with caregivers compensating to avoid patient harm. While recognized in other high risk domains, such human resilience has not yet been described in surgery and has major implications for the design of safety interventions. PMID:22750753

  9. Lymphoscintigraphy and intra-operative gamma probe in detection of sentinel lymph node for breast cancer surgery

    International Nuclear Information System (INIS)

    Le Ngoc Ha; Le Manh Ha; Bui Quang Bieu

    2011-01-01

    Sentinel lymph node biopsy (SLNB) has been emerged as a highly accurate method of axillary staging in management of breast cancer patients. Sentinel lymph node detection (SLND) by lymphoscintigraphy and intra-operative gamma probe for SLNB have been widely used in the world. Objectives: the purpose of our study was to evaluate the result of techniques using lymphoscintigraphy and intra-operative gamma probe for SLND in breast carcinoma patients. Materials and Methods: 102 patients with early breast carcinoma were enrolled in the study. Lymphoscintigraphy using Tc-99m-human serum albumin colloid, intra-operative gamma probe were undergone for localization and SLNB. Total axillary lymph node was dissected in breast cancer surgery. Results: The success rate of lymphoscintigraphy and SLND was 98.0% (100/102 patients), mean number of sentinel lymph node (SLN)/patient was 1.56 ± 0.79 (ranged 1 - 3), number of lymphatic vessel/SLN was 1.5 ± 0.69 (ranged 1 - 4) and mean time for SLND on lymphoscintigraphy was 4.21 ± 13.4 minutes (2 - 15 minutes). The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of radio-guided SLNB for axillary staging was 100%, 70.6%, 41.2%, 100% and 75.6 % respectively. Conclusions: radio-guided SLNB by lymphoscintigraphy and intra-operative gamma probe is feasible and reliable for axillary staging in early breast carcinoma patients. (author)

  10. Operative Treatment of Intra-Articular Distal Radius Fractures With versus Without Arthroscopy : Study protocol for a randomised controlled trial

    NARCIS (Netherlands)

    M.A.M. Mulders (Marjolein A. M.); C.A. Selles (Caroline); J.W. Colaris (Joost); R.W. Peters (Rolf); M. van Heijl (Mark); B.I. Cleffken (Berry); N.W.L. Schep (Niels)

    2018-01-01

    markdownabstract__Background:__ In the past several years, an increase in open reduction and internal fixation (ORIF) for intra-articular distal radius fractures has been observed. This technique leads to a quicker recovery of function compared to non-operative treatment. However, some patients

  11. Operative Treatment of Intra-Articular Distal Radius Fractures With versus Without Arthroscopy: study protocol for a randomised controlled trial

    NARCIS (Netherlands)

    Mulders, Marjolein A. M.; Selles, Caroline A.; Colaris, Joost W.; Peters, Rolf W.; van Heijl, Mark; Cleffken, Berry I.; Schep, Niels W. L.

    2018-01-01

    Background: In the past several years, an increase in open reduction and internal fixation (ORIF) for intra-articular distal radius fractures has been observed. This technique leads to a quicker recovery of function compared to non-operative treatment. However, some patients continue to have a

  12. Intra-operative warming with a forced-air warmer in preventing hypothermia after tourniquet deflation in elderly patients.

    Science.gov (United States)

    Kim, Y-S; Jeon, Y-S; Lee, J-A; Park, W-K; Koh, H-S; Joo, J-D; In, J-H; Seo, K-W

    2009-01-01

    This randomized, single-blind study aimed to explore the effects of intra-operative warming with a forced-air warmer in the prevention of hypothermia after tourniquet deflation in elderly patients undergoing unilateral total knee replacement arthroplasty under general anaesthesia. Patients were randomized to receive either intra-operative warming using a forced-air warmer with an upper body blanket (warming group; n = 12) or no intra-operative warming (nonwarming group; n = 12). Oesophageal temperature was measured as core body temperature. At 30 min following tourniquet inflation, the core body temperature started to increase in the warming group whereas it continued to drop in the non-warming group. This difference was statistically significant. The final core body temperature after tourniquet deflation was significantly higher in the warming group (mean +/- SD 36.1 +/- 0.2 degrees C) than in the non-warming group (35.4 +/- 0.3 degrees C). Intra-operative forced-air warming increased the core body temperature before tourniquet deflation and prevented subsequent hypothermia in elderly patients under general anaesthesia.

  13. Intra-operative ex vivo photoacoustic nodal staging in a rat model using a clinical superparamagnetic iron oxide nanoparticle dispersion

    NARCIS (Netherlands)

    Grootendorst, D.J.; Fratila, R.M.; Visscher, M.; Haken, B.T.; Wezel, R.J.A. van; Rottenberg, S.; Steenbergen, W. van; Manohar, S.; Ruers, T.J.M.

    2013-01-01

    The ability to accurately detect tumor metastases in lymph nodes is essential for intra-operative staging of various malignancies. Histopathological assessment of nodes has the drawback of a time delay before results are available to the surgeon and a likelihood of missing metastases. Photoacoustic

  14. Intra-operative ex vivo photoacoustic nodal staging in a rat model using a clinical superparamagnetic iron oxide nanoparticle dispersion

    NARCIS (Netherlands)

    Grootendorst, Diederik; Fratila, R.M.; Visscher, M.; ten Haken, Bernard; van Wezel, Richard Jack Anton; Rottenberg, S.; Steenbergen, Wiendelt; Manohar, Srirang; Ruers, Theo J.M.

    The ability to accurately detect tumor metastases in lymph nodes is essential for intra-operative staging of various malignancies. Histopathological assessment of nodes has the drawback of a time delay before results are available to the surgeon and a likelihood of missing metastases. Photoacoustic

  15. Influence of physical parameters on radiation protection and image quality in intra-oral radiology

    Energy Technology Data Exchange (ETDEWEB)

    Belinato, W. [Instituto Federal de Ensino Basico, Tecnico e Tecnologico da Bahia, Av. Amazonas, 1350-45030-220, Zabele, Vitoria da Conquista, BA (Brazil); Departamento de Fisica, Universidade Federal de Sergipe, Av. Marechal Rondon s/n, 49100-000 Rosa Elze, Sao Cristovao, SE (Brazil); Souza, D.N., E-mail: divanizi@ufs.br [Departamento de Fisica, Universidade Federal de Sergipe, Av. Marechal Rondon s/n, 49100-000 Rosa Elze, Sao Cristovao, SE (Brazil)

    2011-10-01

    In the world of diagnostic imaging, radiography is an important supplementary method for dental diagnosis. In radiology, special attention must be paid to the radiological protection of patients and health professionals, and also to image quality for correct diagnosis. In Brazil, the national rules governing the operation of medical and dental radiology were specified in 1998 by the National Sanitary Surveillance Agency, complemented in 2005 by the guide 'Medical radiology: security and performance of equipment.' In this study, quality control tests were performed in public clinics with dental X-ray equipment in the State of Sergipe, Brazil, with consideration of the physical parameters that influence radiological protection and also the quality of images taken in intra-oral radiography. The accuracy of the exposure time was considered acceptable for equipment with digital timers. Exposure times and focal-spot size variations can lead to increased entrance dose. Increased dose has also been associated with visual processing of radiographic film, which often requires repeating the radiographic examination.

  16. Influence of physical parameters on radiation protection and image quality in intra-oral radiology

    Science.gov (United States)

    Belinato, W.; Souza, D. N.

    2011-10-01

    In the world of diagnostic imaging, radiography is an important supplementary method for dental diagnosis. In radiology, special attention must be paid to the radiological protection of patients and health professionals, and also to image quality for correct diagnosis. In Brazil, the national rules governing the operation of medical and dental radiology were specified in 1998 by the National Sanitary Surveillance Agency, complemented in 2005 by the guide "Medical radiology: security and performance of equipment." In this study, quality control tests were performed in public clinics with dental X-ray equipment in the State of Sergipe, Brazil, with consideration of the physical parameters that influence radiological protection and also the quality of images taken in intra-oral radiography. The accuracy of the exposure time was considered acceptable for equipment with digital timers. Exposure times and focal-spot size variations can lead to increased entrance dose. Increased dose has also been associated with visual processing of radiographic film, which often requires repeating the radiographic examination.

  17. Influence of physical parameters on radiation protection and image quality in intra-oral radiology

    International Nuclear Information System (INIS)

    Belinato, W.; Souza, D.N.

    2011-01-01

    In the world of diagnostic imaging, radiography is an important supplementary method for dental diagnosis. In radiology, special attention must be paid to the radiological protection of patients and health professionals, and also to image quality for correct diagnosis. In Brazil, the national rules governing the operation of medical and dental radiology were specified in 1998 by the National Sanitary Surveillance Agency, complemented in 2005 by the guide 'Medical radiology: security and performance of equipment.' In this study, quality control tests were performed in public clinics with dental X-ray equipment in the State of Sergipe, Brazil, with consideration of the physical parameters that influence radiological protection and also the quality of images taken in intra-oral radiography. The accuracy of the exposure time was considered acceptable for equipment with digital timers. Exposure times and focal-spot size variations can lead to increased entrance dose. Increased dose has also been associated with visual processing of radiographic film, which often requires repeating the radiographic examination.

  18. [Inflammatory pseudotumour of the liver. Importance of intra-operative histopathology].

    Science.gov (United States)

    Onieva-González, Francisco Gabriel; Galeano-Díaz, Francisco; Matito-Díaz, María José; López-Guerra, Diego; Fernández-Pérez, Juana; Blanco-Fernández, Gerardo

    2015-01-01

    Inflammatory pseudotumour is a rare entity, considered benign, and characterised by inflammatory cell mesenchymal proliferation. The case is presented 70 year-old man with fever of unknown origin syndrome. He was diagnosed with liver abscesses (one segment IV, adjacent to gallbladder fundus and segment VI), who progressed slowly after antibiotic treatment. In the absence of a diagnosis, although fine needle puncture-aspiration and different imaging tests were performed, elective surgery was decided. The intra-operative histopathology reported the existence of an inflammatory pseudotumour. Inflammatory pseudotumours are clinically classified into different types according to their aetiology, varying therapeutic management based on the same. It is very difficult to diagnose because of the absence of symptoms, blood disorders, or specific radiological findings. Definitive diagnosis often requires histopathological confirmation, in most cases by percutaneous liver puncture, but sometimes exploratory laparotomy or even performing a hepatectomy for confirmation is necessary. The natural history of inflammatory pseudotumour is its regression; thus conservative management may be used through regular checks until resolution, or can be treated with antibiotics, anti-inflammatories and even corticosteroids. Surgical resection is indicated for persistent unresolved systemic symptoms despite medical treatment, in those situations where growth is evident, with or without symptoms, when involving the hepatic hilum, and finally, in case where the possibility of malignancy cannot be ruled out. Copyright © 2015 Academia Mexicana de Cirugía A.C. Published by Masson Doyma México S.A. All rights reserved.

  19. Operative versus nonoperative treatment of displaced intra-articular calcaneal fractures

    Science.gov (United States)

    Wei, Ning; Yuwen, Peizhi; Liu, Wei; Zhu, Yanbin; Chang, Wenli; Feng, Chen; Chen, Wei

    2017-01-01

    Abstract Background: The relative efficacy of operative and nonoperative treatments for the displaced intra-articular calcaneal fractures (DIACF) remains uncertain. Object: We conducted a meta-analysis to compare the effectiveness of operative and nonoperative treatments in treating patients with DIACF. Methods: Databases including Cochrane Library, Medline, Embase, CBM, CNKI, and Google Scholar were searched. After independent study selection by 2 authors, data were extracted and collected independently. Comparisons were performed between operative treatment group and nonoperative treatment group. The quality of included studies was assessed using the Newcastle–Ottawa Scale. RevMan 5.3 was used for data analysis. The primary outcome measures were anatomical measures (changes in Böhler angle and calcaneal height and width), functional measures (shoe problems, resuming preinjury work, and residual pain), and complications (including superficial and deep wound infection, skin flap necrosis, neurovascular injury, secondary arthrodesis, reflex sympathetic dystrophy, osteotomy, thromboembolism, and compartment syndromes). Results: Eighteen trials (8 randomized controlled trials and 10 controlled clinical trials) including 1467 patients were considered. For anatomical measurements, the overall mean differences (MDs) for the mean Böhler angle, calcaneal height and width were 15.39 (95% confidence interval [CI] 9.12–21.67), 6.55 (95% CI 2.67–10.43), and 7.05 (95% CI −7.83 to −6.27), respectively. In functional measures, the overall effect MD of American Orthopedic Foot and Ankle Society was 6.23 (95% CI 5.22–17.67) and 0.38 (95% CI 0.22–0.67). The overall relative risks (RRs) of wearing shoes, resuming preinjury work, and having residual pain were 0.32 (95% CI 0.32–1.00), 0.56 (95% CI 0.40–0.77), and 0.90 (95% CI 0.68–1.20), respectively. The overall RR of the incidence of complications was 2.00 (95% CI 1.51–2.64). Conclusion: Operative treatment of

  20. Operational and safety requirement of radiation facility

    International Nuclear Information System (INIS)

    Zulkafli Ghazali

    2007-01-01

    Gamma and electron irradiation facilities are the most common industrial sources of ionizing radiation. They have been used for medical, industrial and research purposes since the 1950s. Currently there are more than 160 gamma irradiation facilities and over 600 electron beam facilities in operation worldwide. These facilities are either used for the sterilization of medical and pharmaceutical products, the preservation of foodstuffs, polymer synthesis and modification, or the eradication of insect infestation. Irradiation with electron beam, gamma ray or ultra violet light can also destroy complex organic contaminants in both liquid and gaseous waste. EB systems are replacing traditional chemical sterilization methods in the medical supply industry. The ultra-violet curing facility, however, has found more industrial application in printing and furniture industries. Gamma and electron beam facilities produce very high dose rates during irradiation, and thus there is a potential of accidental exposure in the irradiation chamber which can be lethal within minutes. Although, the safety record of this industry has been relatively very good, there have been fatalities recorded in Italy (1975), Norway (1982), El Salvador (1989) and Israel (1990). Precautions against uncontrolled entry into irradiation chamber must therefore be taken. This is especially so in the case of gamma irradiation facilities those contain large amounts of radioactivity. If the mechanism for retracting the source is damaged, the source may remain exposed. This paper will, to certain extent, describe safety procedure and system being installed at ALURTRON, Nuclear Malaysia to eliminate accidental exposure of electron beam irradiation. (author)

  1. Dose optimization of intra-operative high dose rate interstitial brachytherapy implants for soft tissue sarcoma

    Directory of Open Access Journals (Sweden)

    Jamema Swamidas

    2009-01-01

    Full Text Available Objective : A three dimensional (3D image-based dosimetric study to quantitatively compare geometric vs. dose-point optimization in combination with graphical optimization for interstitial brachytherapy of soft tissue sarcoma (STS. Materials and Methods : Fifteen consecutive STS patients, treated with intra-operative, interstitial Brachytherapy, were enrolled in this dosimetric study. Treatment plans were generated using dose points situated at the "central plane between the catheters", "between the catheters throughout the implanted volume", at "distances perpendicular to the implant axis" and "on the surface of the target volume" Geometrically optimized plans had dose points defined between the catheters, while dose-point optimized plans had dose points defined at a plane perpendicular to the implant axis and on the target surface. Each plan was graphically optimized and compared using dose volume indices. Results : Target coverage was suboptimal with coverage index (CI = 0.67 when dose points were defined at the central plane while it was superior when the dose points were defined at the target surface (CI=0.93. The coverage of graphically optimized plans (GrO was similar to non-GrO with dose points defined on surface or perpendicular to the implant axis. A similar pattern was noticed with conformity index (0.61 vs. 0.82. GrO were more conformal and less homogeneous compared to non-GrO. Sum index was superior for dose points defined on the surface of the target and relatively inferior for plans with dose points at other locations (1.35 vs. 1.27. Conclusions : Optimization with dose points defined away from the implant plane and on target results in superior target coverage with optimal values of other indices. GrO offer better target coverage for implants with non-uniform geometry and target volume.

  2. Intra-operative parathyroid hormone monitoring through central laboratory is accurate in renal secondary hyperparathyroidism.

    Science.gov (United States)

    Vulpio, Carlo; Bossola, Maurizio; Di Stasio, Enrico; Pepe, Gilda; Nure, Eda; Magalini, Sabina; Agnes, Salvatore

    2016-05-01

    The usefulness, the methods and the criteria of intra-operative monitoring of the parathyroid hormone (ioPTH) during parathyroidectomy (PTX) for renal secondary hyperparathyroidism (rSHPT) in patients on chronic hemodialysis remain still matter of debate. The present study aimed to evaluate the ability of a low cost central-laboratory second generation PTH assay to predict an incomplete resection of parathyroid glands (PTG). The ioPTH decay was determined In 42 consecutive patients undergoing PTX (15 subtotal and 27 total without auto-transplant of PTG) for rSHPT. The ioPTH monitoring included five samples: pre-intubation, post-manipulation of PTG and at 10, 20 and 30min post-PTG excision. The patients with PTH exceeding the normal value (65pg/ml) at the first postoperative week, 6 and 12months were classified as persistent rSHPT. The concentrations of ioPTH declined significantly over time in patients who received total or subtotal PTX; however, no difference was found between the two types of PTX. Irrespective of the type of PTX and the number of PTG removed, combining the absolute and percentage of ioPTH decay at 30min after PTG excision, we found high sensitivity (100%), specificity (92%), negative predictive value (100%) and accuracy (93%) in predicting the persistence of rSHPT. The monitoring of the ioPTH decline by a low cost central-laboratory second generation assay is extremely accurate in predicting the persistence of disease in patients on maintenance hemodialysis undergoing surgery for rSHPT. Copyright © 2016 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  3. Hemodynamic effects of dexmedetomidine during intra-operative electrocorticography for epilepsy surgery

    Directory of Open Access Journals (Sweden)

    G Chaitanya

    2014-01-01

    Full Text Available Background: Dexmedetomidine, a predominant alpha-2-adrenergic agonist has been used in anesthetic practice to provide good sedation. The drug is being recently used in neuroanesthesia during awake surgery for brain tumors and in functional neurosurgery. Materials and Methods: This prospective study analyzed the hemodynamic effects of dexmedetomidine infusion during electrocorticography in patients undergoing surgery for mesial temporal sclerosis. Dexmedetomidine infusion was administered during intra-operative electrocorticography recording, 15 minutes after the end tidal MAC of N 2 O and isoflurane were decreased to zero. Anesthesia was maintained with O 2 :air mixture = 50:50, vecuronium and fentanyl. Heart rate (HR, mean arterial pressure (MAP and end tidal carbon dioxide (ETCO 2 were recorded across at induction, 2 min prior to dexmedetomidine (PreDEX, 5 min during dexmedetomidine infusion (DEX; 1 μg/kg, 5 min after stopping dexmedetomidine and 10 minutes after stopping dexmedetomidine. Results: Forty patients with mesial temporal sclerosis (M: F = 27:13, mean age = 28.15 ± 10.9 years; duration of epilepsy = 12.0 ± 7.9 years underwent anterior temporal lobe resection with amygdalohippocampectomy for drug-resistant epilepsy. Infusion of dexmedetomidine caused a transient fall in HR in 87.5% of patients and an increase in MAP in 62.5% of patients, which showed a tendency to revert back towards PreDEX values within 10 min after stopping the infusion. Sixty-five percent of the patients showed ≤25% reduction and 10% of them showed >25% reduction in HR. 47.5% of the patients showed ≤25% increase and 15% of them showed >25% increase in MAP. These changes were over a narrow range and within physiological limits. Conclusion: The infusion of dexmedetomidine for a short period causes reduction of HR and increase in MAP in patients, however the variations are within acceptable range.

  4. Imaging of spatially extended hot spots with coded apertures for intra-operative nuclear medicine applications

    Science.gov (United States)

    Kaissas, I.; Papadimitropoulos, C.; Potiriadis, C.; Karafasoulis, K.; Loukas, D.; Lambropoulos, C. P.

    2017-01-01

    Coded aperture imaging transcends planar imaging with conventional collimators in efficiency and Field of View (FOV). We present experimental results for the detection of 141 keV and 122 keV γ-photons emitted by uniformly extended 99mTc and 57Co hot-spots along with simulations of uniformly and normally extended 99mTc hot-spots. These results prove that the method can be used for intra-operative imaging of radio-traced sentinel nodes and thyroid remnants. The study is performed using a setup of two gamma cameras, each consisting of a coded-aperture (or mask) of Modified Uniformly Redundant Array (MURA) of rank 19 positioned on top of a CdTe detector. The detector pixel pitch is 350 μm and its active area is 4.4 × 4.4 cm2, while the mask element size is 1.7 mm. The detectable photon energy ranges from 15 keV up to 200 keV with an energy resolution of 3-4 keV FWHM. Triangulation is exploited to estimate the 3D spatial coordinates of the radioactive spots within the system FOV. Two extended sources, with uniform distributed activity (11 and 24 mm in diameter, respectively), positioned at 16 cm from the system and with 3 cm distance between their centers, can be resolved and localized with accuracy better than 5%. The results indicate that the estimated positions of spatially extended sources lay within their volume size and that neighboring sources, even with a low level of radioactivity, such as 30 MBq, can be clearly distinguished with an acquisition time about 3 seconds.

  5. The effect of body mass index on fluoroscopy time and radiation dose in intra-articular glenohumeral joint injections.

    Science.gov (United States)

    Mattie, Ryan; McCormick, Zachary L; Fogg, Benjamin; Cushman, Daniel M

    To determine the relationship between body mass index (BMI) and fluoroscopy time and radiation dose during fluoroscopy-guided glenohumeral joint injections. This was a retrospective analysis of prospectively collected data. Physicians with board certification in Physical Medicine and Rehabilitation and/or Sports Medicine performed or supervised all injections. BMI was calculated within three months of the injection. Fluoroscopy time and radiation dose data were recorded by the fluoroscopy system and transcribed into the clinical database after each procedure. A total of 335 intra-articular GHJ injections were performed, 230 on the right shoulder and 105 on the left shoulder; none were bilateral. The mean fluoroscopy time for all injections was 18.8±12.6s, and the mean radiation DAP was 656±1190mGy-cm2. There was no significant difference in fluoroscopy time or dose between first-time and repeat injections (P=.405; P=.011) and no significant differences in fluoroscopy time or radiation dose when a trainee was involved (P=.756 for time and P=.149 for dose). Needle lengths of 1.5, 2.5, or 3.5in. were used during the injection, and there was no significant difference in needle length selection between BMI groups (P=.319). Intra-articular glenohumeral joint injection fluoroscopy time and radiation dose are not affected by body mass index, age, gender, trainee-involvement, first versus repeat injection, or needle length. This procedure is associated with a dose of radiation that likely has minimal to no clinical significance. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Potential radiation doses from 1994 Hanford Operations

    International Nuclear Information System (INIS)

    Soldat, J.K.; Antonio, E.J.

    1995-01-01

    This section of the 1994 Hanford Site Environmental Report summarizes the potential radiation doses to the public from releases originating at the Hanford Site. Members of the public are potentially exposed to low-levels of radiation from these effluents through a variety of pathways. The potential radiation doses to the public were calculated for the hypothetical MEI and for the general public residing within 80 km (50 mi) of the Hanford Site

  7. Intra-operative assessment of femoral antetorsion using ISO-C 3D: a cadaver study.

    Science.gov (United States)

    Hawi, Nael; Suero, Eduardo M; Liodakis, Emmanouil; Decker, Sebastian; Krettek, Christian; Citak, Musa

    2014-03-01

    The aim of this study was to check the feasibility and accuracy of measuring antetorsion during surgery using a mobile image intensifier (IF) with computed tomography (CT) function (ISO-C 3D; Siemens, Erlangen, Germany) in comparison to a conventional multi-slice CT scanner (LightSpeed QX/I CT; GE Healthcare, VA, USA). A total of 10 intact femora with intact soft tissue of five fresh frozen cadavers were used. After fixation on a surgical table, IF CT scans of the hip and knee were performed at both 190° and 120° of scanning rotation. Afterwards, a conventional CT scan was performed. Antetorsion was calculated according to the method of Jend et al. Analysis of variance (ANOVA) and Lin's concordance correlation coefficient (LCC) were used to test the agreement between the three measurement techniques. There was no significant difference in femoral antetorsion angle measurements between the different techniques (P>0.05). The mean time required to perform a scan using the ISO-C 3D was 9±3 min. The mean time required to measure antetorsion was 8±2 min. We found a high positive correlation between CT-based measurements and measurements performed using both the ISO-C 3D at 190° (LCC=0.99; mean difference=0.02°±1.8°) and the ISO-C 3D at 120° (LCC=0.99; mean difference=0.6°±1.5°), and a high positive correlation was also seen between both ISO-C 3D methods (LCC=0.99; mean difference=0.6°±1.7°). Measuring femoral antetorsion using an intra-operative IF with CT function is a feasible and accurate method. This technique could be used when there is doubt about the antetorsion angle in the operated femur and it could help decrease the need for a separate revision surgery. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. Beliefs and values about intra-operative teaching and learning: a case study of surgical teachers and trainees.

    Science.gov (United States)

    Ong, Caroline C P; Dodds, Agnes; Nestel, Debra

    2016-08-01

    Surgeons require advanced psychomotor skills, critical decision-making and teamwork skills. Much of surgical skills training involve progressive trainee participation in supervised operations where case variability, operating team interaction and environment affect learning, while surgical teachers face the key challenge of ensuring patient safety. Using a theoretical framework of situated learning including cognitive apprenticeship, we explored teachers' and trainees' beliefs and values about intra-operative training and reasons for any differences. A qualitative case study method was used where five teacher-trainee pairs participating in an observed teaching operation were separately interviewed about the same operation. Thematic analysis of transcribed interviews and observations was performed with iterative refinement and a reflexive approach was adopted throughout the study. We found that in all cases, teachers and trainees had shared recognition of learning about technical skills whereas they differed in three cases regarding non-technical skills such as surgical reasoning and team management. Factors contributing to teacher and trainee satisfaction with the process were successful trainee completion of operation without need for surgeon take-over, a positive learning environment and learning new things. Teaching-learning behaviours observed and discussed were modeling, coaching and scaffolding, while exploration, reflection and articulation were less common. Our study reveals differing teacher and trainee perspectives of some aspects of intra-operative training and surfaces new reasons other than amount of feedback and autonomy given. Factors contributing to different perspectives include teacher and trainee abilities, values and situational influences. Targeted teaching-learning strategies could enhance intra-operative learning.

  9. Study on method for using operational radiation quantities for radiation monitoring

    International Nuclear Information System (INIS)

    Shen Tingyun; Qian Jianfu

    2000-01-01

    The concept and meaning of operational radiation quantities for radiation monitoring were discussed, the method and contain and application were also expounded, the reliability of equipment can be risen, so the measurement is in agreement with international measure

  10. Histopathological studies of radiation-combined intra-arterial chemotherapy on squamous cell carcinoma of the mandible

    International Nuclear Information System (INIS)

    Yonemochi, Takemi

    1996-01-01

    The 2nd Department of Oral and Maxillofacial Surgery, Faculty of Dentistry Hospital, Iwate Medical University has performed radiation-combined intra-arterial chemotherapy as a preoperative treatment and subsequent mandibulectomy. During a 20 year-period from 1975 to 1994, clinical and histopathological examination of the above therapy was made for its effect and usefulness by using 15 primary cases of mandibular gingival squamous cell carcinoma, which were all identifiable. Roentgenological examination by bone resorptive pattern (invasive type, erosive type) and by bone resorptive depth (degree 0-III) revealed that early infiltration case and advanced case were predominant in the erosive type and the invasive type respectively. Histopathologically, the therapeutical effect of the radiation-combined intra-arterial chemotherapy on the tumor cells was examined using osteoclast, fibrous connective tissue, osteoblast, new bone, site of neoosteogenesis, and post-treatment site of residual tumor ceils as findings in the healing process. The histological therapeutic effect was good on well-differentiated type cases, and the histological effect on osteo-infiltrated region was as good as, or better than on soft tissue region. The cases with good histological therapeutic effect scarcely showed osteoclast, but showed remarkable hyperplasia of fibrous connective tissue, appearance of osteoblast and repair mechanism via neoosteogenesis. Invasive type tumor was persistent in the depth of the mandible, while erosive type tumor showed a tendency to be persistent in superficial layer. The results suggested that the application of the present radiation-combined intra-arterial chemotherapy to mandibular gingival squamous cell carcinoma is very useful leading to the improvement in radical curability of the tumor in its primary focus and the preservation of mandibular continuity in surgery. (author)

  11. The clinical effect of combination therapy for oral cancer with S-1, superselective intra-arterial chemotherapy, and radiation therapy

    International Nuclear Information System (INIS)

    Yamamoto, Chika; Yoshikawa, Hiromasa; Fukumoto, Shunsuke; Higuchi, Takashi; Yoshida, Masanori; Yasumori, Koutarou; Horinouchi, Yasufumi; Uehara, Satoru

    2011-01-01

    Combination therapy with S-1, superselective intra-arterial infusion of carboplatin (CBDCA) and radiation therapy has been used to treat patients with oral cancer since 2005. In this study, the histopathological effects and toxicities following concurrent chemoradiotherapy were examined. The subjects consisted of 15 patients (10 men and 5 women) who were treated with S-1 (60-80 mg/day, 4 weeks), superselective intra-arterial infusion of CBDCA (300 mg/body) and radiation therapy (total dose 30-36 Gy) in our department from 2005 to 2009. Nine patients, showed T2 disease, 3 showed T3 disease, and another 3 showed T4 diseases. The primary cancer sites were the tongue (6 cases), buccal mucosa (4 cases), mandible gingival (3 cases), maxillary gingival (1 case), and the floor of the mouth (1 case). The histopathological effects were evaluated according to Oboshi-Shimosato classification. Grade IV was shown in 10 cases (66.7%), grade III in 1 case (6.7%), II bin 3 cases (20.0%), and II a in 1 case (6.7%). All patients completed the treatment. The pathological response of the resected tumor was grade IIb or higher in 14 cases (93.3%). While good histological effects were noted, there was one patient for whom viable tumor cells remained in the central part of the tumor. The present study indicates that further investigation is needed to determine the best dosing and dosing schedule. (author)

  12. Use of auditory evoked potentials for intra-operative awareness in anesthesia: a consciousness-based conceptual model.

    Science.gov (United States)

    Dong, Xuebao; Suo, Puxia; Yuan, Xin; Yao, Xuefeng

    2015-01-01

    Auditory evoked potentials (AEPs) have been used as a measure of the depth of anesthesia during the intra-operative process. AEPs are classically divided, on the basis of their latency, into first, fast, middle, slow, and late components. The use of auditory evoked potential has been advocated for the assessment of Intra-operative awareness (IOA), but has not been considered seriously enough to universalize it. It is because we have not explored enough the impact of auditory perception and auditory processing on the IOA phenomena as well as on the subsequent psychological impact of IOA on the patient. More importantly, we have seldom tried to look at the phenomena of IOP from the perspective of consciousness itself. This perspective is especially important because many of IOA phenomena exist in the subconscious domain than they do in the conscious domain of explicit recall. Two important forms of these subconscious manifestations of IOA are the implicit recall phenomena and post-operative dreams related to the operation. Here, we present an integrated auditory consciousness-based model of IOA. We start with a brief description of auditory awareness and the factors affecting it. Further, we proceed to the evaluation of conscious and subconscious information processing by auditory modality and how they interact during and after intra-operative period. Further, we show that both conscious and subconscious auditory processing affect the IOA experience and both have serious psychological implications on the patient subsequently. These effects could be prevented by using auditory evoked potential during monitoring of anesthesia, especially the mid-latency auditory evoked potentials (MLAERs). To conclude our model with present hypothesis, we propose that the use of auditory evoked potential should be universal with general anesthesia use in order to prevent the occurrences of distressing outcomes resulting from both conscious and subconscious auditory processing during

  13. Validation of intra-operative parathyroid hormone and its decline as early predictors of hypoparathyroidism after total thyroidectomy: A prospective cohort study.

    Science.gov (United States)

    Gupta, Shailesh; Chaudhary, Poras; Durga, Chikkala K; Naskar, Dipankar

    2015-06-01

    Total thyroidectomy is a preferred surgical technique for benign as well as malignant thyroid pathologies, but many a times can cause hypoparathyroidism. The aim of this study is to evaluate the intra-operative parathyroid hormone (ioPTH) level and its decline as predictors for post-operative hypoparathyroidism after total thyroidectomy. In this single-centre prospective cohort study, 90 patients who underwent total thyroidectomy for benign as well as malignant pathologies of thyroid gland were studied. Intra-operative parathyroid levels and at different time intervals parathyroid hormone and serum calcium levels were measured to predict hypoparathyroidism. The data was analysed using independent sample t test and p value hypoparathyroidism. Intra-operative PTH was found to be most accurate predictor for diagnosing post-operative hypoparathyroidism (cut off was (11.3 pg/ml, calculated using ROC curves) and has maximum sum of sensitivity (91.7%) and specificity (97%). On taking cut off values of intra-operative PTH and PTH decline together, they were found to be most accurate predictor for permanent hypoparathyroidism. Early and accurate predictor of hypoparathyroidism is very important and always sought. Very early prediction during intra-operative periods can be used for auto transplantation of parathyroid gland. Intra-operative parathyroid hormone and its decline are accurate, reliable, and early predictor of hypoparathyroidism after total thyroidectomy. Copyright © 2015 IJS Publishing Group Limited. Published by Elsevier Ltd. All rights reserved.

  14. Does pre-operative sampling predict intra-operative cultures and antibiotic sensitivities in knee replacements revised for infection?: a study using the NJR dataset.

    Science.gov (United States)

    Holleyman, Richard J; Deehan, David J; Charlett, Andre; Gould, Kate; Baker, Paul N

    2016-10-01

    This study examined a cohort of primary knee arthroplasties revised for peri-prosthetic infection to (1) determine whether the microorganisms isolated by sampling (up to 6 months pre-operatively) are representative of the microorganisms encountered at the time of knee revision, (2) determine whether the antibiotic sensitivity profiles of matching organisms correlate and (3) determine whether the proportion of organism and antibiotic sensitivity matches is influenced by the type of infection, timing of sample collection and the type of microorganism isolated. From the National Joint Registry database for England and Wales, a consecutive series of primary knee arthroplasties performed between 2003 and 2014 that went on to have a revision for peri-prosthetic infection were identified. Each case was then linked to a national microbiology database held by Public Health England. Following data linkage, intra-operative and pre-operative cultures were identified and compared in a group of 75 patients. Pre-operative genus matched intra-operative genus in 56 of 75 cases (75 %). Of those 56, the corresponding antimicrobial sensitivities matched in 37 (66 % of cases). Overall, 37 of 75 cases (49 %) matched for both microorganism and antimicrobial sensitivity. The proportion of matches was highest in the pure Staphylococcal genus infections (genus match 88 %, sensitivity match 62 %, genus and sensitivity match 55 %) and lowest in those patients with mixed organism infections (genus match 29 %, sensitivity match 14 %). Pre-operative joint sampling obtained by either aspiration or tissue biopsy is advocated in cases where peri-prosthetic infection is suspected and provides the only means of determining infecting organism prior to revision. Overall, only half of all pre-operative cultures matched completely the findings of intra-operative samples in terms of both the microorganism(s) encountered and their corresponding antimicrobial sensitivity profile. Clinicians should

  15. High Operating Temperature, Radiation-Hard MIM Thermophotovoltaic Converters Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Spire Corporation proposes to investigate InGaAs thermophotovoltaic (TPV) cells optimized for high temperature operation (~150C) and radiation hardness against the...

  16. Standard Guide for Radiation Protection Program for Decommissioning Operations

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    1987-01-01

    1.1 This guide provides instruction to the individual charged with the responsibility for developing and implementing the radiation protection program for decommissioning operations. 1.2 This guide provides a basis for the user to develop radiation protection program documentation that will support both the radiological engineering and radiation safety aspects of the decommissioning project. 1.3 This guide presents a description of those elements that should be addressed in a specific radiation protection plan for each decommissioning project. The plan would, in turn, form the basis for development of the implementation procedures that execute the intent of the plan. 1.4 This guide applies to the development of radiation protection programs established to control exposures to radiation and radioactive materials associated with the decommissioning of nuclear facilities. The intent of this guide is to supplement existing radiation protection programs as they may pertain to decommissioning workers, members of...

  17. Psychological and mobile evaluation of intra-uterus children exposed to the radiation with cesium-137

    International Nuclear Information System (INIS)

    Ferreira, Celia Marly

    1995-01-01

    The presented work had as objective the accomplishment of a comparative study of cesium-137 radioactive element effects in the psychological and motor development of children which were going submitted the intra-uterus irradiation during the chronological age of three years. The comparison of the results of study is done through a group-control composed for five children without any involvement with the cesium-137 accident - occurred in 1987 in Goiania, Brazil - of same social, economic and cultural level and with the same age of the reached

  18. Reproducibility of a Digital Method to Evaluate Soft Tissue Modifications: A study of Inter and Intra-Operative Measurement Concordance

    Science.gov (United States)

    Rancitelli, Davide; Cicciù, Marco; Lini, Francesco; Fumagalli, Davide; Frigo, Anna Chiara; Maiorana, Carlo

    2017-01-01

    Background: The soft tissue healing and quality around dental implant is a current debated topic in the recent literature. The free gingival margin and the quantity and quality of the mucosa around teeth and surrounding dental implants still determine the hard and soft tissue healing status. Objective: The aim of this study is to assess inter and intra-operative measurement concordance of a method aimed at evaluating the apico-coronal migration of free gingival margin, using intra-oral photography. Methods: The method was tested on peri-implant tissues that were treated with a connective tissue graft on the second stage surgery. Thirty-eight measurements on 13 implants in 8 patients were recorded. An intra-oral photograph was taken for the graft and the provisional crown, which enclosed a circular landmark with a previously determined diameter. The landmark was prepared with a red-resin by the same technician. Before crown cementation, the landmark was calibrated with a digital calibrator by the main investigator, to determine the precise diameter up to two decimal numbers. Results: On the intra-oral photograph, the distance was measured from the most apical point of the determined landmark to the zenith of the gingiva, using an image-processing program designed for scientific multidimensional images (Image J). Three independent examiners took these measurements. Conclusion: The main advantage of the present non-invasive technique is that the spatial plane of the prosthetic landmarks is the same of the tooth unlike the utilization of periodontal probe, which is generally positioned on different plans in the space (generally more vestibular). PMID:28567141

  19. The incidence of intra-operative awareness during general anesthesia in China: a multi-center observational study.

    Science.gov (United States)

    Xu, L; Wu, A-S; Yue, Y

    2009-08-01

    The incidence of awareness in patients undergoing general anesthesia is 0.1-0.2% in Western countries. The medical literatures about awareness during general anesthesia are still rare in China, but some previous studies have reported a higher incidence (1.4-6%) of intra-operative awareness. To find out the reason why the incidence reported in China is much higher than that in Western countries, we performed a prospective, multicenter, non-randomized observational study to determine the true incidence of intra-operative awareness in China. This is a prospective, non-randomized descriptive cohort study that was conducted at 25 academic medical centers in China. Eleven thousand one hundred and eighty-five patients were interviewed by research staff for evaluation of awareness at the first and fourth day after general anesthesia with muscle relaxation. An independent blinded committee evaluated the responses and determined whether awareness occurred. Necessary data were collected for a binary logistic regression analysis. Data from 11,101 patients were presented. Forty-six cases (0.41%) were reported as definite awareness and 47 additional cases (0.41%) as possible awareness. Three hundred and fifty-five patients (3.19%) had dreams during general anesthesia. Awareness was associated with increased American Society of Anesthesiologists (ASA) physical status, a previous anesthesia, and anesthesia methods of total intravenous anesthesia. The incidence of intra-operative awareness in China is approximately 0.41%, two to three times higher than that widely cited in Western countries. Inappropriately light anesthesia, and the population proportion of surgery and general anesthesia in China may account for the difference. (ClinicalTrials.gov Identifier, NCT00693875.).

  20. Online signal processing of internal anal sphincter activity during pelvic autonomic nerve stimulation: a new method to improve the reliability of intra-operative neuromonitoring signals.

    Science.gov (United States)

    Kauff, D W; Koch, K P; Somerlik, K H; Heimann, A; Hoffmann, K P; Lang, H; Kneist, W

    2011-12-01

    Intra-operative neuromonitoring is increasingly applied in several surgical disciplines and has been introduced to facilitate pelvic autonomic nerve preservation. Nevertheless, it has been considered a questionable tool for the minimization of risk, as the results are variable and might be misleading. The aim of the present experimental study was to develop an intra-operative neuromonitoring system with improved reliability for monitoring pelvic autonomic nerve function. Fifteen pigs underwent low anterior rectal resection with pelvic autonomic nerve preservation. Intra-operative neuromonitoring was performed under autonomic nerve stimulation with observation of electromyographic signals of the internal anal sphincter and bladder manometry. As the internal anal sphincter frequency spectrum during stimulation was found to be mainly in the range of 5-20 Hz, intra-operative neuromonitoring signals were postoperatively processed by implementation of matching band pass filters. In 10 preliminary experiments, signal processing was performed offline in the postoperative analysis. Of 163 stimulations intra-operatively assessed by the surgeon as positive responses, 135 (83%) were confirmed after signal processing. In the following five consecutive experiments intra-operative online signal processing was realized and demonstrated reliable intra-operative neuromonitoring signals of internal anal sphincter activity with significant increase during pelvic autonomic nerve stimulation [0.5 μV (interquartile range = 0.3-0.7) vs 4.8 μV (interquartile range = 2.5-7.5); P signal processing of internal anal sphincter activity aids reliable identification of pelvic autonomic nerves with potential for improvement of intra-operative neuromonitoring in pelvic surgery. © 2011 The Authors. Colorectal Disease © 2011 The Association of Coloproctology of Great Britain and Ireland.

  1. The use of high-field intra-operative magnetic resonance imaging combined with language functional neuronavigation in glioma surgery

    OpenAIRE

    Yan ZHAO; Xiao-lei CHEN; Fei WANG; Guo-chen SUN; Yu-bo WANG; Zhi-jun SONG; Bai-nan XU

    2011-01-01

    Objective To explore the effect of high-field intra-operative magnetic resonance imaging(iMRI) combined with language functional neuronavigation in resection of glioma in language area of dominant hemisphere of the brain.Methods Twenty right handed patients(12 males and 8 females,aged from 20 to 61 years with mean of 43.6 years) with glioma close to arcuate fasciculus were involved in present study,and they were stratified into normal group(n=9) and aphasia group(n=11) according to the preope...

  2. NCRP Program Area Committee 2: Operational Radiation Safety

    Energy Technology Data Exchange (ETDEWEB)

    Pryor, Kathryn H.; Goldin, Eric M.

    2016-02-29

    Program Area Committee 2 of the National Council on Radiation Protection and Measurements provides guidance for radiation safety in occupational settings in a variety of industries and activities. The committee completed three reports in recent years covering recommendations for the development and administration of radiation safety programs for smaller educational institutions, requirements for self-assessment programs that improve radiation safety and identify and correct deficiencies, and a comprehensive process for effective investigation of radiological incidents. Ongoing work includes a report on sealed radioactive source controls and oversight of a report on radioactive nanomaterials focusing on gaps within current radiation safety programs. Future efforts may deal with operational radiation safety programs in fields such as the safe use of handheld and portable X-Ray fluorescence analyzers, occupational airborne radioactive contamination, unsealed radioactive sources, or industrial accelerators.

  3. Operational Radiation Protection in veterinary centres

    International Nuclear Information System (INIS)

    Cordon, E.; Vigil, A.; Coll, A.

    2012-01-01

    Nowadays, there is a trend towards the use of digital radiography in the veterinary field. As a consequence, there could be a workload increase in the X-ray system and higher exposure for veterinarians and members of the public. In this study we analyze the influence of the X-ray machine output with with the radiation levels at the veterinarian position. We have considered the leads apron that each veterinarian center has and we have related its attenuation coefficient with the dose exposure at the veterinarian position. With the maximum workload, we have made a theoretical assessment for the primary barrier at 1 m of the X-ray focus.Despite there is a workload increase due to the digital technologies, the studied results show that is is very unlikely to be in excess of annual dose limit for the exposed workers. (Author) 5 refs.

  4. Accuracy of intra-operative frozen section and its role in the diagnostic evaluation of ovarian tumors.

    Science.gov (United States)

    Abudukadeer, A; Azam, S; Zunong, B; Mutailipu, A Zuoremu; Huijun, B; Qun, L

    2016-01-01

    Summary This retrospective study was undertaken to evaluate the accuracy and role of intra-operative frozen section in the diagnosis of ovarian tumors. Retrospective study of 804 ovarian frozen section results between June 2010 and June 2014 was examined to determine the accuracy of frozen section diagnosis. The intra-operative frozen section diagnosis was compared with the permanent (paraffin) section and the overall accuracy, sensitivity, specificity, and positive and negative predictive values of the frozen section were studied. The overall accuracy to determine the status of malignancy was 92.6%. There were 38 (7.4%) false negative and no false positive frozen section diagnoses.The sensitivity, specificity, and positive predictive and negative predictive values for benign ovarian tumors were 100.0%, 97.0%, 91.3%, and 100.0%, respectively; for borderline tumors they were 64.3%, 97.0%, 91.5%, and 94.0%, respectively, and for malignant tumors they were 90.0%, 100.0%, 100.0%, and 85.5%, respectively. This study concluded that frozen section appears to be an adequate technique for the histopathological diagnosis of ovarian tumors, with some limitations observed among borderline and mucinous tumors.

  5. The use of high-field intra-operative magnetic resonance imaging combined with language functional neuronavigation in glioma surgery

    Directory of Open Access Journals (Sweden)

    Yan ZHAO

    2011-07-01

    Full Text Available Objective To explore the effect of high-field intra-operative magnetic resonance imaging(iMRI combined with language functional neuronavigation in resection of glioma in language area of dominant hemisphere of the brain.Methods Twenty right handed patients(12 males and 8 females,aged from 20 to 61 years with mean of 43.6 years with glioma close to arcuate fasciculus were involved in present study,and they were stratified into normal group(n=9 and aphasia group(n=11 according to the preoperative aphasia quotient(AQ.All the patients underwent surgical operation assisted by arcuate fasciculus navigator,and the high-field iMRI was performed with a 1.5-T magnetic resonance scanner.The 3D reconstructed arcuate fasciculus images were integrated into neuronavigation system before the operation,and used by combining with functional neuronavigation under microscope during the surgical procedure.Pre-operatirely,and 2-4 weeks,3-6 months postoperative,the patients were examined with magnetic resonance scanning and aphasia quotients examination.Results Pre-operative and intra-operative arcuate fasciculus reconstruction was completed in all the 20 patients,and neuronavigation under microscope were performed after the 3D images integrated into neuronavigation system.Patients of normal AQ(94.5±5.5 retained the normal level,except one patients who developed new conduction aphasia syndrome(AQ=81.8 2-4 weeks after operation.The AQ of aphasia group(89.4±5.8 was significantly improved than that before operation(84.9±8.7,P < 0.05,except 2 patients whose language deficit was exacerbated due to tumor recurrence.The AQ of normal group(98.3±0.5 remained at normal level,while that of aphasia group(95.2±2.6 was significantly improved 3-6 months after operation compared with that at 2-4 weeks after operation(P < 0.05.There were no other new neurologic deficits and death in both groups.Conclusion High-field iMRI combined with functional neuronavigation is a safe and

  6. Intra-arterial cisplatin and concurrent radiation for invasive bladder cancer

    International Nuclear Information System (INIS)

    Miyanaga, Naoto; Ohtani, Mikinobu; Noguchi, Ryosuke

    1991-01-01

    Fifteen patients with invasive bladder cancer were treated with selective intra-arterial cisplatin and external beam radiotherapy (30.6 Gy over 3 weeks) prior to a planned cystectomy. Cisplatin, in total 200 mg, was administered via bilateral internal iliac artery infusion during the course of radiotherapy. Seven patients were evaluated for local response. Partial response (PR) was revealed in 4, and minor response (MR) in 3. Ten patients received total cystectomy, and pathological effects by the criteria adipted by Japanese Urological Association and The Japanese Society of Pathology, were as follows: Ef.3 in 1 case, Ef.2 in 6. Ef.1b in 1 and Ef.1a in 2. Down staging was observed in 8 patients from the clinical to the pathological stage. Thirteen patients are alive for 21 months. Two patients have died (1 lung infarction, 1 pancreatic cancer). Though nausea and sciatica-like pain were observed in some cases, there were no severe systemic side effects such as bone marrow suppression and renal toxicity. From these results it is concluded that this therapeutic modality could be effective in the preoperative work-up of candidates for total cystectomy, and also that it could be useful in the treatment of patients in whom total cystectomy is contraindicated. (author)

  7. Intra-arterial cisplatin and concurrent radiation for invasive bladder cancer

    Energy Technology Data Exchange (ETDEWEB)

    Miyanaga, Naoto; Ohtani, Mikinobu; Noguchi, Ryosuke (Tsukuba Univ., Ibaraki (Japan). Inst. of Clinical Medicine) (and others)

    1991-10-01

    Fifteen patients with invasive bladder cancer were treated with selective intra-arterial cisplatin and external beam radiotherapy (30.6 Gy over 3 weeks) prior to a planned cystectomy. Cisplatin, in total 200 mg, was administered via bilateral internal iliac artery infusion during the course of radiotherapy. Seven patients were evaluated for local response. Partial response (PR) was revealed in 4, and minor response (MR) in 3. Ten patients received total cystectomy, and pathological effects by the criteria adipted by Japanese Urological Association and The Japanese Society of Pathology, were as follows: Ef.3 in 1 case, Ef.2 in 6. Ef.1b in 1 and Ef.1a in 2. Down staging was observed in 8 patients from the clinical to the pathological stage. Thirteen patients are alive for 21 months. Two patients have died (1 lung infarction, 1 pancreatic cancer). Though nausea and sciatica-like pain were observed in some cases, there were no severe systemic side effects such as bone marrow suppression and renal toxicity. From these results it is concluded that this therapeutic modality could be effective in the preoperative work-up of candidates for total cystectomy, and also that it could be useful in the treatment of patients in whom total cystectomy is contraindicated. (author).

  8. Operating experience on radiation reduction in the latest BWRs

    International Nuclear Information System (INIS)

    Ohsumi, K.; Uchida, S.; Aizawa, M.; Takagi, K.; Amano, O.; Yamashita, K.

    1988-01-01

    In Japan, BWR plants have been operated commercially since 1970, and the reduction of radiation exposure has been an important concern. The application of the procedure for reducing occupational exposure is incorporated in Japanese Improvement and Standardization Program for LWRs. No.2 and No.4 plants in Fukushima No.2 Nuclear Power Station were designed and constructed as the latest 1,100 MWe BWRs in conformity with the Improvement and Standardization Program. No.2 plant began the commercial operation in February, 1984, and experienced three times of the scheduled annual maintenance outage. No.4 plant began the commercial operation in September, 1987, and the first annual maintenance is scheduled from September, 1988. In this paper, discussion is focused on recent radiation reduction measures, that is the control of iron and nickel in primary coolant for reducing the radiation dose rate in primary systems, based on the experience with No.2 and No.4 plants. The design concept of a low radiation dose rate nuclear power plant, the experience on water chemistry in No.2 plant, the control of iron and nickel in No.4 plant operation and so on are reported. It is believed that these operation experiences contribute to the reduction of occupational exposure in BWR plants currently in operation and in future. (Kako, I.)

  9. Posterior facet cartilage injury in operatively treated intra-articular calcaneus fractures.

    Science.gov (United States)

    Rothberg, David L; Yoo, Brad J

    2014-10-01

    Direct visualization of the posterior facet in displaced intra-articular calcaneus fractures (DIACF) frequently shows partial or full thickness cartilage delamination. This is felt to be secondary to the depression of an osteoarticular segment of the posterior facet within the calcaneal body and the subsequent contact with fracture edges as it impacts caudally. The purpose of this study was to determine the frequency of cartilage injury and if it correlates with fracture classification. A single surgeon prospective, observational series of 28 patients with 28 DIACFs was reviewed for patient demographic and injury data, radiographic fracture characterization, and intraoperative observation of articular injury size, depth, and location over the time period of February 2010 to December 2012. Observations were correlated with the OTA and Sanders classification systems. Age, sex, mechanism of injury, and depth and location of cartilage injury were not significantly different between the 13 OTA/Sanders type 2 and 15 type 3 DIACFs evaluated in this study. Posterior facet articular cartilage delamination was found in 77% of type 2 and 100% of type 3 fractures (P = .09). Location of cartilage injury was common (56%) along the distal, lateral aspect of the posterior facet (P fractures (3.1%) then type 2 (1.3%) (P fractures compared to type 2 fractures. Level IV, prospective, observational series. © The Author(s) 2014.

  10. Intra-operative remifentanil might influence pain levels in the immediate post-operative period after major abdominal surgery

    DEFF Research Database (Denmark)

    Hansen, E G; Duedahl, T H; Rømsing, J

    2005-01-01

    Remifentanil, a widely used analgesic agent in anaesthesia, has a rapid onset and short duration of action. In clinical settings, this requires an appropriate pain strategy to prevent unacceptable pain in the post-operative period. The aim of this study was to investigate whether remifentanil had...... any impact on post-operative pain and opioid consumption after major abdominal surgery....

  11. Radiation safety in 'install and operate type' irradiator

    International Nuclear Information System (INIS)

    Sahoo, D.K.; Kohli, A.K.

    2003-01-01

    Install and operate type irradiator has been designed to carry out radiation processing of various food products as well as medical products. It is a category 1 type batch irradiator. This paper brings out the radiation safety aspects of this irradiator. Comparison has been made with conveyor type category IV irradiators, which are more common in use for commercial purposes. The design has many features that make it a very safe, convenient and economical method for processing of all items that are permitted and amenable for gamma radiation processing. (author)

  12. Operation of radiation monitoring system in radwaste form test facility

    International Nuclear Information System (INIS)

    Ryu, Young Gerl; Kim, Ki Hong; Lee, Jae Won; Kwac, Koung Kil

    1998-08-01

    RWFTF (RadWaste Form Test Facility) must have a secure radiation monitoring system (RMS) because of having a hot-cell capable of handling high radioactive materials. And then in controlled radiation zone, which is hot-cell and its maintenance and operation / control room, area dose rate, radioactivities in air-bone particulates and stack, and surface contamination are monitored continuously. For the effective management such as higher utilization, maintenance and repair, the status of this radiation monitoring system, the operation and characteristics of all kinds of detectors and other parts of composing this system, and signal treatment and its evaluation were described in this technical report. And to obtain the accuracy detection results and its higher confidence level, the procedure such as maintenance, functional check and system calibration were established and appended to help the operation of RMS. (author). 6 tabs., 30 figs

  13. Radiation dose to the operator during fluoroscopically guided spine procedures

    Energy Technology Data Exchange (ETDEWEB)

    Roccatagliata, Luca; Pravata, Emanuele; Cianfoni, Alessandro [Department of Neuroradiology, Neurocenter of Southern Switzerland, Ospedale Regionale di Lugano, Lugano (Switzerland); Presilla, Stefano [Unita di Fisica Medica, Ente Ospedaliero Cantonale (EOC), Bellinzona (Switzerland)

    2017-09-15

    Fluoroscopy is widely used to guide diagnostic and therapeutic spine procedures. The purpose of this study was to quantify radiation incident on the operator (operator Air Kerma) during a wide range of fluoroscopy-guided spine procedures and its correlation with the amount of radiation incident on the patient (Kerma Area Product - KAP). We retrospectively included 57 consecutive fluoroscopically guided spine procedures. KAP [Gy cm{sup 2}] and total fluoroscopy time were recorded for each procedure. An electronic dosimeter recorded the operator Air Kerma [μGy] for each procedure. Operator Air Kerma for each procedure, correlation between KAP and operator Air Kerma, and between KAP and fluoroscopy time was obtained. Operator Air Kerma was widely variable across procedures, with median value of 6.4 μGy per procedure. Median fluoroscopy time and median KAP per procedure were 2.6 min and 4.7 Gy cm{sup 2}, respectively. There was correlation between operator Air Kerma and KAP (r{sup 2} = 0.60), with a slope of 1.6 μGy Air Kerma per unit Gy cm{sup 2} KAP incident on the patient and between fluoroscopy time and KAP (r{sup 2} = 0.63). Operator Air Kerma during individual fluoroscopy-guided spine procedures can be approximated from the commonly and readily available information of the total amount of radiation incident on the patient, measured as KAP. (orig.)

  14. The Use of Patient-Specific Intra-Operative Guides for Total Knee Arthroplasty (TKA

    Directory of Open Access Journals (Sweden)

    Hendrik P. Delport

    2012-08-01

    Conclusions: We conclude that this novel technique hereby described has major benefits: less operative time and proper implant positioning, but more prospective studies are mandatory. [Arch Clin Exp Surg 2012; 1(4.000: 206-212

  15. Intra-operative techniques to reduce the risk of capsular contracture in patients undergoing aesthetic breast augmentation - A review.

    Science.gov (United States)

    Horsnell, J D; Searle, A E; Harris, P A

    2017-10-01

    Capsular contracture is a significant complication following aesthetic breast augmentation. Efforts to reduce this incidence have focused on the surgical approach, implant selection and IV antibiotics. Intra-operative methods to reduce the risk have had less investigation. This review focuses on these interventions and will document evidence to support pocket irrigation, nipple shields, drains and the use of an implant insertion funnel. A comprehensive review of Pubmed, Scopus and Embase was performed to identify relevant papers published since 2000. These were reviewed and pertinent papers selected. Data regarding the intervention and its impact were recorded and compared. Ten relevant studies were identified. A total of 11,772 patients were included in the studies, with a pooled capsular contracture rate of 2.54%. Six papers reported the use of antibiotic irrigation, two papers reported the use of drains, two the use of an insertion funnel, two the use of povidone-iodine and one the use of nipple shields. Antibiotic irrigation was shown to reduce capsular contracture 10 fold in two papers, have no effect in one and increase it in a further paper. However these changes did not persist after multivariate analysis. There was limited evidence to support intra-operative techniques to reduce capsular contracture rate. Where available the literature tends to support the use of antibiotic and povidone-iodine irrigation, the use of insertion funnels and nipple shields and the avoidance of drains. However due to the poor quality of the evidence these findings should be treated cautiously. Copyright © 2017 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.

  16. Intra-operative prostate motion tracking using surface markers for robot-assisted laparoscopic radical prostatectomy

    Science.gov (United States)

    Esteghamatian, Mehdi; Sarkar, Kripasindhu; Pautler, Stephen E.; Chen, Elvis C. S.; Peters, Terry M.

    2012-02-01

    Radical prostatectomy surgery (RP) is the gold standard for treatment of localized prostate cancer (PCa). Recently, emergence of minimally invasive techniques such as Laparoscopic Radical Prostatectomy (LRP) and Robot-Assisted Laparoscopic Radical Prostatectomy (RARP) has improved the outcomes for prostatectomy. However, it remains difficult for the surgeons to make informed decisions regarding resection margins and nerve sparing since the location of the tumor within the organ is not usually visible in a laparoscopic view. While MRI enables visualization of the salient structures and cancer foci, its efficacy in LRP is reduced unless it is fused into a stereoscopic view such that homologous structures overlap. Registration of the MRI image and peri-operative ultrasound image using a tracked probe can potentially be exploited to bring the pre-operative information into alignment with the patient coordinate system during the procedure. While doing so, prostate motion needs to be compensated in real-time to synchronize the stereoscopic view with the pre-operative MRI during the prostatectomy procedure. In this study, a point-based stereoscopic tracking technique is investigated to compensate for rigid prostate motion so that the same motion can be applied to the pre-operative images. This method benefits from stereoscopic tracking of the surface markers implanted over the surface of the prostate phantom. The average target registration error using this approach was 3.25+/-1.43mm.

  17. Pre-operative planning and intra-operative guidance in modern neurosurgery: a review of 300 cases.

    Science.gov (United States)

    Wadley, J.; Dorward, N.; Kitchen, N.; Thomas, D.

    1999-01-01

    Operative neurosurgery has recently entered an exciting era of image guided surgery or neuronavigation and application of this novel technology is beginning to have a significant impact in many ways in a variety of intracranial procedures. In order to fully assess the advantages of image guided techniques over conventional planning and surgery in selected cases, detailed prospective evaluation has been carried out during the advanced development of an optically tracked neuronavigation system. Over a 2-year period, 300 operative neurosurgical procedures have been performed with the assistance of interactive image guidance, as well as the development of new software applications and hardware tools. A broad range of intracranial neurosurgical procedures were seen to benefit from image guidance, including 163 craniotomies, 53 interactive stereotactic biopsies, 7 tracked neuroendoscopies and 37 complex skull base procedures. The most common pathological diagnoses were cerebral glioma in 98 cases, meningioma in 64 and metastasis in 23. Detailed analysis of a battery of postoperative questions revealed benefits in operative planning, appreciation of anatomy, lesion location, safety of surgery and greatly enhanced surgical confidence. The authors believe that image guided surgical technology, with new developments such as those described, has a significant role to play in contemporary neurosurgery and its widespread adoption in practice will be realised in the near future. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 PMID:10615186

  18. Radiation protection during operation of nuclear power plants

    International Nuclear Information System (INIS)

    1983-01-01

    This Guide describes a Radiation Protection Programme for nuclear power plants. It includes: (1) An outline of the basic principles as well as practical aspects of the programme; (2) A description of the responsibilities of the operating organization to establish an effective programme based upon these principles; (3) A description of the administrative and technical measures to establish and implement the programme. This Guide also deals with the operational aspects to be considered by the operating organization in reviewing design in order to facilitate implementation of the Radiation Protection Programme. This Guide covers the requirements for a Radiation Protection Programme for all operational states of the nuclear power plant. It also includes guidelines for handling planned special exposures and for coping with unplanned exposures and contamination of personnel, areas, and equipment. Additional information concerning emergency situations involving releases of radioactive materials is given in Safety Guides 50-SG-O6, ''Preparedness of the Operating Organization (Licensee) for Emergencies at Nuclear Power Plants'', and 50-SG-G6, ''Preparedness of Public Authorities for Emergencies at Nuclear Power Plants''. This Guide covers the principles of dose limitation to site personnel and to the public, but it does not include detailed instructions on the techniques used for the actual measurement and evaluation of the exposures. This Guide does not include detailed instructions on environmental surveys, but it does mention principal steps in environmental monitoring which may be required for confirmation of the acceptability of radioactive discharges

  19. Anti-tumor effects of cold atmospheric pressure plasma on vestibular schwannoma demonstrate its feasibility as an intra-operative adjuvant treatment.

    Science.gov (United States)

    Yoon, Yeo Jun; Suh, Michelle J; Lee, Hyun Young; Lee, Hae June; Choi, Eun Ha; Moon, In Seok; Song, Kiwon

    2018-02-01

    Vestibular schwannoma (VS), although a benign intracranial tumor, causes morbidities by brainstem compression. Since chemotherapy is not very effective in most Nf2-negative schwannomas, surgical removal or radiation therapy is required. However, depending on the size and site of the tumor, these approaches may cause loss of auditory or vestibular functions, and severely decrease the post-surgical wellbeing. Here, we examined the feasibility of cold atmospheric pressure plasma (CAP) as an intra-operative adjuvant treatment for VS after surgery. Cell death was efficiently induced in both human HEI-193 and mouse SC4 VS cell lines upon exposure to CAP for seven minutes. Interestingly, both apoptosis and necroptosis were simultaneously induced by CAP treatment, and cell death was not completely inhibited by pan-caspase and receptor-interacting serine/threonine-protein kinase 1 (RIK1) inhibitors. Upon CAP exposure, cell death phenotype was similarly observed in patient-derived primary VS cells and tumor mass. In addition, CAP exposure after the surgical removal of primary tumor efficiently inhibited tumor recurrence in SC4-grafted mouse models. Collectively, these results strongly suggest that CAP should be developed as an efficient adjuvant treatment for VS after surgery to eliminate the possible remnant tumor cells, and to minimize the surgical area in the brain for post-surgical wellbeing. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. Estimation and comparison of intra operative blood loss in patients with and without venous thromboembolism prophylaxis

    International Nuclear Information System (INIS)

    Ahsin, S.; Bashir, A.; Faiz, S.A.; Tahir, J.; Ijaz, A.

    2014-01-01

    To estimate and compare intraoperative blood loss in surgical patients with and without deep vein thrombosis (DVT) prophylaxis using unfractionated heparin Study Design: Clinical Trial Place and Duration: Surgery Department of Fauji Foundation Hospital and Physiology Department Foundation University Medical College from October 2011 to August 2012 Patients and Methodology: Patients were selected by non probability purposive sampling. Patients fulfilling the inclusion criteria were divided into 2 groups 25 each on the basis of order of presentation at Fauji Foundation Hospital until cohort numbers were reached. Group I received no heparin whereas group II received heparin. Written informed consent was taken from the patient after explaining the procedure of the study. Coagulation profile was done for both groups before the planned surgery. Heparin in a dose of 5000 units was administered subcutaneously to group II on the morning of the planned surgery and it was stopped 24 hours post operatively. Blood loss was estimated in both groups by weighing cotton swabs pre and post operatively. Data was analyzed by SPSS version 17. Results: Demographic data and surgical procedure time between the two groups did not differ. Blood loss between the two groups did not show any statistically significant difference. Conclusion: DVT prophylaxis using unfractionated heparin did not lead to any significant overt blood loss when compared with those without it. (author)

  1. Maintenance operations and radiation protection in french nuclear power plants

    International Nuclear Information System (INIS)

    Godin, R.; Stricker, L.

    1990-01-01

    In the field of radiation protection, the Service de la Production thermique (the Thermal and fossil generation division, SPT) at EDF aims at being among the best and at keeping for EDF agents an exposure potential allowing them to act in an emergency case. Doses to EDF or subcontractors' workers must therefore be optimized during maintenance operations. These aims can be reached through special techniques and by a know-how of the actors at several levels: 1) upstream, operating the plant with a clean primary circuit (which limits dose rates) and solubilizing corrosion products during reactor cooling and primary circuit drainage; 2) before the intervention, thorough preparation of the work and operation of protection means suited to each site; 3) during the intervention, the actors' know-how requires suitable training and qualification of the operation leader, awareness of all the actors and, sometimes training on mockup; 4) finally, for special operations on account of their repetitiveness or because they take place in hostile places, special tools are developed. The techniques thus developed, the systematic use of feedback have made it possible to reach a most acceptable result. Radiation protection proceeds from the maintenance operation quality and thus shares in improving the operation safety of the french nuclear power plants. 5 figs.; 3 refs [fr

  2. Prototype Operational Advances for Atmospheric Radiation Dose Rate Specification

    Science.gov (United States)

    Tobiska, W. K.; Bouwer, D.; Bailey, J. J.; Didkovsky, L. V.; Judge, K.; Garrett, H. B.; Atwell, W.; Gersey, B.; Wilkins, R.; Rice, D.; Schunk, R. W.; Bell, D.; Mertens, C. J.; Xu, X.; Crowley, G.; Reynolds, A.; Azeem, I.; Wiltberger, M. J.; Wiley, S.; Bacon, S.; Teets, E.; Sim, A.; Dominik, L.

    2014-12-01

    Space weather's effects upon the near-Earth environment are due to dynamic changes in the energy transfer processes from the Sun's photons, particles, and fields. The coupling between the solar and galactic high-energy particles, the magnetosphere, and atmospheric regions can significantly affect humans and our technology as a result of radiation exposure. Space Environment Technologies (SET) has developed innovative, new space weather observations that will become part of the toolset that is transitioned into operational use. One prototype operational system for providing timely information about the effects of space weather is SET's Automated Radiation Measurements for Aerospace Safety (ARMAS) system. ARMAS will provide the "weather" of the radiation environment to improve aircraft crew and passenger safety. Through several dozen flights the ARMAS project has successfully demonstrated the operation of a micro dosimeter on commercial aviation altitude aircraft that captures the real-time radiation environment resulting from Galactic Cosmic Rays and Solar Energetic Particles. The real-time radiation exposure is computed as an effective dose rate (body-averaged over the radiative-sensitive organs and tissues in units of microsieverts per hour); total ionizing dose is captured on the aircraft, downlinked in real-time via Iridium satellites, processed on the ground into effective dose rates, compared with NASA's Langley Research Center (LaRC) most recent Nowcast of Atmospheric Ionizing Radiation System (NAIRAS) global radiation climatology model runs, and then made available to end users via the web and smart phone apps. We are extending the dose measurement domain above commercial aviation altitudes into the stratosphere with a collaborative project organized by NASA's Armstrong Flight Research Center (AFRC) called Upper-atmospheric Space and Earth Weather eXperiment (USEWX). In USEWX we will be flying on the ER-2 high altitude aircraft a micro dosimeter for

  3. Rapid intra-operative diagnosis of kidney cancer by attenuated total reflection infrared spectroscopy of tissue smears.

    Science.gov (United States)

    Pucetaite, Milda; Velicka, Martynas; Urboniene, Vidita; Ceponkus, Justinas; Bandzeviciute, Rimante; Jankevicius, Feliksas; Zelvys, Arunas; Sablinskas, Valdas; Steiner, Gerald

    2018-01-09

    Herein, a technique to analyze air-dried kidney tissue impression smears by means of attenuated total reflection infrared (ATR-IR) spectroscopy is presented. Spectral tumor markers-absorption bands of glycogen-are identified in the ATR-IR spectra of the kidney tissue smear samples. Thin kidney tissue cryo-sections currently used for IR spectroscopic analysis lack such spectral markers as the sample preparation causes irreversible molecular changes in the tissue. In particular, freeze-thaw cycle results in degradation of the glycogen and reduction or complete dissolution of its content. Supervised spectral classification was applied to the recorded spectra of the smears and the test spectra were classified with a high accuracy of 92% for normal tissue and 94% for tumor tissue, respectively. For further development, we propose that combination of the method with optical fiber ATR probes could potentially be used for rapid real-time intra-operative tissue analysis without interfering with either the established protocols of pathological examination or the ordinary workflow of operating surgeon. Such approach could ensure easier transition of the method to clinical applications where it may complement the results of gold standard histopathology examination and aid in more precise resection of kidney tumors. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. Technology development for evaluation of operational quantities in radiation protection

    International Nuclear Information System (INIS)

    Jang, Si Young; Lee, T. Y.; Kim, B. H.

    2003-03-01

    Korean government recently published a national regulation on the internal exposure monitoring and dose evaluation (internal dosimetry) based on the most recent ICRP recommendation 60 and subsequent publications, which supercede the former ICRP recommendation 26 and publication 30, on which the internal dosimetry practice in Korea had been based so far. Consequently, this project, according to the demand from both government and nuclear industry, had been launched to develop a user-friendly computer code on internal dosimetry adopting the most up to date ICRP biokinetic and dosimetric model to resolve the difficulties and problems faced to nuclear industry and to develop related technology. The reliability of this code, named as BiDAS, as a result of several benchmark calculations for self assurance appeared to be excellent comparing with the foreign computer code. This computer code is expected to be successfully utilized in nuclear industry and related fields in complying with the national regulation on internal dosimetry program started from late 2003. Reference low level gamma(γ) radiation field for calibration of environmental radiation(γ) monitor and reference neutron field for calibration of n monitoring equipment have been established and characterized. International cross comparison of these reference radiation fields have been performed and radiation response of various radiation monitoring instrument has been tested by using these reference radiation fields. A technology which can directly measure the radiation quality factor and tissue absorbed dose has been established to evaluate the neutron dose in terms of operational quantity in the unknown mixed n-γ radiation field. Spherical and cylindrical TEPC systems have been designed and manufactured and a portable TEPC system to measure the neutron quality and dose in the real work field has been developed and tested in accelerator laboratory

  5. Intra-operative Assessment of the Spinal Cord Function: Awakening Compared to Ankle Clonus Test

    International Nuclear Information System (INIS)

    Amin, Wafik A.; Tealab, Ayman I.; Ei-Gendy, Eslah H.; Esmat, Hesham A.

    2006-01-01

    The spinal cord is at high risk of injury during special procedures such as correction of scoliosis. Recovery from impairement is directly proportional to the time of removal of the instrumentations. For this, methods used to detect the neurologic injury should be continuous, fast, sensitive and specific. The present study was performed to evaluate the ankle clonus as a test for the integrity of the spinal cord function intraoperatively. Twenty eight scoliotic patients were included in the study. The ankle clonus was tested before, during and after the correction and fixation followed by the wake-up test to correlate the results of both rests. The haemodynamics changes at the time of the two tests were compared. It was found out that, the ankle clonus test correlated well with the wake-up test, with only two false positive results. No false negative results were recorded which was an important finding. The haemodynamic changes were better during the ankle clonus test than during the wake-up test. It was concluded that the ankle clonus test is reliable, safe, and faster than the wake-up test. It is recommended to use the test to evaluate the integrity of the spinal cord during the operations with potential risk to the cord. In case the result of the ankle clonus is positive, the wake-up test should be done before an attempt to release or remove the instrumentations. (author)

  6. Near-infrared laparoscopy for real-time intra-operative arterial and lymphatic perfusion imaging.

    LENUS (Irish Health Repository)

    Cahill, R A

    2012-02-01

    Multimodal laparoscopic imaging systems possessing the capability for extended spectrum irradiation and visualization within a unified camera system are now available to provide enhanced intracorporeal operative anatomic and dynamic perfusion assessment and potentially augmented patient outcome. While ultraviolet-range energies have limited penetration and hence are probably more useful for endoscopic mucosal interrogation, the near-infrared (NIR) spectrum is of greater potential utility for the purposes of examining inducible fluorescence in abdominopelvic tissue that can be achieved by administration of specific tracer agents, either directly into the circulation (e.g. for anastomotic perfusion assessment at the time of stapling) or into the lymphatic system (e.g. for lymph basin road-mapping and\\/or focussed target nodal assessment). This technology is also capable of supplementing anatomic recognition of the biliary system while implantable fibres can also be inserted intraoperatively for the purpose of safeguarding vital structures such as the oesphagus and ureters especially in difficult reoperations. It is likely that this technological capability will find a clear and common indication in colorectal specialist and general surgical departments worldwide in the near future.

  7. Pre-operative and intra-operative detection of axillary lymph node metastases in 108 patients with invasive lobular breast cancer undergoing mastectomy.

    Science.gov (United States)

    Novak, Jerica; Besic, Nikola; Dzodic, Radan; Gazic, Barbara; Vogrin, Andrej

    2018-02-05

    Despite the recent changes in the treatment of the axilla in selected breast cancer patient, positive sentinel lymph node (SLN) in patients undergoing mastectomy still necessitates axillary lymph node dissection (ALND). In invasive lobular carcinoma (ILC), pre-operative detection of the lymph node metastasis may be demanding due to its unique morphology. The aim of this study was to examine the benefit of preoperative axillary ultrasound (AUS), ultrasound-guided fine-needle aspiration biopsy (US-FNAB), and intra-operative imprint cytology (IIC), in order to avoid two-stage axillary surgery in patients with ILC undergoing mastectomy. The object of this study were 102 patients (median age 52, range 34-73 years) with clinically non-suspicious axilla in whom 108 mastectomies were performed after a pre-operative AUS investigation. Whenever a metastasis was detected in a sentinel lymph node, ALND was done. Reports of the pre-operative AUS investigation, US-FNAB, and IIC were compared with definitive histopathological reports of surgical specimens. In 46 cases lymph node metastases were diagnosed. AUS suspicious lymph nodes were found in 29/108 cases and histopathology confirmed metastases in 22/30 cases. US-FNAB was performed in 29 cases with AUS suspicious lymph nodes. Cytology proved metastases in 11/29 cases. Histopathology confirmed metastases in 10/11 cases with only isolated tumor cells found in one case. IIC investigation was performed in 63 cases and in 10/27 cases metastases were confirmed by histopathology. Pre-operative AUS, US-FNAB, and/or IIC investigation enabled ALND during a single surgical procedure in 20/46 patients with metastases in lymph nodes. Pre-operative AUS, US-FNAB, and/or IIC are/is beneficial in patients with ILC planned for mastectomy in order to decrease the number of two stage axillary procedures.

  8. Fluorocholangiography: reincarnation in the laparoscopic era-evaluation of intra-operative cholangiography in 3635 laparoscopic cholecystectomies.

    Science.gov (United States)

    Nassar, Ahmad H M; Mirza, Ahmad; Qandeel, Haitham; Ahmed, Zubir; Zino, Samer

    2016-05-01

    The introduction of laparoscopic cholecystectomy (LC) resulted in the decline of routine intra-operative cholangiography (IOC). Common bile duct stones are being diagnosed preoperatively using magnetic resonance cholangiopancreatography (MRCP). We aim to evaluate the use and benefits of IOC during laparoscopic biliary surgery at a high-volume biliary surgery unit. Prospective data from 4088 patients undergoing LC over 22 years were analysed. Referral protocols allow one firm to receive the great majority of biliary emergencies and all suspected ductal stones. All patients with gall stones on ultrasound scanning, fit for surgery, will undergo LC during the index admission. MRCP and ERCP are not part of preoperative investigation. A four-port LC is performed with a size 5Fr ureteric catheter within an open cannula to obtain an IOC through right sub-costal port. Of 4088 patients, IOC was attempted in 3691 (90.2 %) and 3635 had a successful IOC (98.4 %). 75 % were females. The mean age was 59 years. Patients presented with one or more of the following: chronic biliary pain in 60 %, acute pain 26.7 %, acute cholecystitis 8.4 %, gallstone pancreatitis 7.8 % and jaundice with or without cholangitis in 19.2 %. A total of 1328 patients (36.5 %) had risk factors for CBD stones. The IOC was abnormal in 975 cases (26.8 %), recording 1599 abnormalities. IOC identified 774 patients with CBD stones (21.3 %), including previously unsuspected CBD stones in 4.7 %. IOC was false negative in 20 cases (0.5 %) found to have stones on basket exploration. A decision not to perform IOC in 453 cases (11 %) was made preoperatively in 74.2 % and intra-operatively in 12.3 %. IOC can be safely and routinely performed in LC. It helps to identify CBD stones, even in patients with no known risk factors, delineate bile duct anatomy and facilitate single-stage management of CBD stones.

  9. Rotational X-ray angiography: a method for intra-operative volume imaging of the left-atrium and pulmonary veins for atrial fibrillation ablation guidance

    Science.gov (United States)

    Manzke, R.; Zagorchev, L.; d'Avila, A.; Thiagalingam, A.; Reddy, V. Y.; Chan, R. C.

    2007-03-01

    Catheter-based ablation in the left atrium and pulmonary veins (LAPV) for treatment of atrial fibrillation in cardiac electrophysiology (EP) are complex and require knowledge of heart chamber anatomy. Electroanatomical mapping (EAM) is typically used to define cardiac structures by combining electromagnetic spatial catheter localization with surface models which interpolate the anatomy between EAM point locations in 3D. Recently, the incorporation of pre-operative volumetric CT or MR data sets has allowed for more detailed maps of LAPV anatomy to be used intra-operatively. Preoperative data sets are however a rough guide since they can be acquired several days to weeks prior to EP intervention. Due to positional and physiological changes, the intra-operative cardiac anatomy can be different from that depicted in the pre-operative data. We present an application of contrast-enhanced rotational X-ray imaging for CT-like reconstruction of 3D LAPV anatomy during the intervention itself. Depending on the heart size a single or two selective contrastenhanced rotational acquisitions are performed and CT-like volumes are reconstructed with 3D filtered back projection. In case of dual injection, the two volumes depicting the left and right portions of the LAPV are registered and fused. The data sets are visualized and segmented intra-procedurally to provide anatomical data and surface models for intervention guidance. Our results from animal and human experiments indicate that the anatomical information from intra-operative CT-like reconstructions compares favorably with preacquired imaging data and can be of sufficient quality for intra-operative guidance.

  10. Reconstruction accuracy of a dedicated localiser for filmless planning in intra-operative brachytherapy

    International Nuclear Information System (INIS)

    Kolkman-Deurloo, Inger-Karine K.; Visser, Andries G.; Idzes, Marjolein H.M.; Levendag, Peter C.

    1997-01-01

    Background and purpose: With the use of HDR and PDR afterloaders containing a single stepping source, brachytherapy dose distributions can be optimised by varying the source dwell time. With the goal of implementing 'conformal brachytherapy', i.e. ensuring that the dose distribution conforms as accurately as possible to the target volume, we evaluated a set-up which enabled on-line implant localisation and dose planning during implantation. Materials and methods: The set-up, designated as an integrated brachytherapy unit (IBU), consists of a shielded operating room equipped with an HDR afterloader and a dedicated brachytherapy localiser connected to a treatment planning computer. The localiser is isocentric and has an extra degree of freedom in comparison to conventional simulators (i.e. an L-arm in combination with a C-arm) and enables viewing of the implant from any direction. A reconstruction algorithm which takes into account both rotation axes, i.e. the L-arm and C-arm angle, was developed for the localiser. The reconstruction procedure was tested by using the IBU localiser to measure the reconstruction accuracy with a phantom (containing 25 markers at well defined positions) and using reconstruction from radiographs. These results were compared to simulations where the accuracy of reconstruction was determined as a function of the reconstruction angle and the accuracy of read-outs of the localiser settings. On-line localisation and dose planning during implantation is based on filmless planning, i.e. fluoroscopy images and the corresponding localiser settings are imported into the treatment planning computer during implantation. The accuracy of filmless planning was determined using fluoroscopy images in the same set-up as for the experiments with the radiographs. The effect of reconstruction inaccuracies on the total irradiation time and the dose in target or normal tissue points was elucidated for clinically relevant implant geometries. The treatment plans

  11. The ALICE Transition Radiation Detector: construction, operation, and performance

    OpenAIRE

    Acharya, Shreyasi; Adam, Jaroslav; Ahmad, Nazeer; Bhattacharjee, Buddhadeb; Turrisi, Rosario; Tveter, Trine Spedstad; Ullaland, Kjetil; Umaka, Ejiro Naomi; Uras, Antonio; Usai, Gianluca; Utrobicic, Antonija; Vala, Martin; Van Der Maarel, Jasper; Van Hoorne, Jacobus Willem; Bhom, Jihyun

    2018-01-01

    The Transition Radiation Detector (TRD) was designed and built to enhance the capabilities of the ALICE detector at the Large Hadron Collider (LHC). While aimed at providing electron identification and triggering, the TRD also contributes significantly to the track reconstruction and calibration in the central barrel of ALICE. In this paper the design, construction, operation, and performance of this detector are discussed. A pion rejection factor of up to 410 is achieved at a momentum of 1 G...

  12. Intra-operative rapid diagnostic method based on CK19 mRNA expression for the detection of lymph node metastases in breast cancer

    NARCIS (Netherlands)

    Visser, Mike; Jiwa, Mehdi; Horstman, Anja; Brink, Antoinette A. T. P.; Pol, Rene P.; van Diest, Paul; Snijders, Peter J. F.; Meijer, Chris J. L. M.

    2008-01-01

    Staging by sentinel node (SN) biopsy is the standard procedure for clinically node-negative breast cancer patients. Intra-operative analysis of the SN allows immediate axillary lymph node (ALN) dissection in SN positive patients, but a quick, reliable and reproducible method is lacking. We tested

  13. Extended endoscopic endonasal surgery using three-dimensional endoscopy in the intra-operative MRI suite for supra-diaphragmatic ectopic pituitary adenoma.

    Science.gov (United States)

    Fuminari, Komatsu; Hideki, Atsumi; Manabu, Osakabe; Mitsunori, Matsumae

    2015-01-01

    We describe a supra-diaphragmatic ectopic pituitary adenoma that was safely removed using the extended endoscopic endonasal approach, and discuss the value of three-dimensional (3D) endoscopy and intra-operative magnetic resonance imaging (MRI) to this type of procedure. A 61-year-old-man with bitemporal hemianopsia was referred to our hospital, where MRI revealed an enhanced suprasellar tumor compressing the optic chiasma. The tumor extended on the planum sphenoidale and partially encased the right internal carotid artery. An endocrinological assessment indicated normal pituitary function. The extended endoscopic endonasal approach was taken using a 3D endoscope in the intraoperative MRI suite. The tumor was located above the diaphragma sellae and separated from the normal pituitary gland. The pathological findings indicated non-functioning pituitary adenoma and thus the tumor was diagnosed as a supra-diaphragmatic ectopic pituitary adenoma. Intra-operative MRI provided useful information to minimize dural opening and the supra-diaphragmatic ectopic pituitary adenoma was removed from the complex neurovascular structure via the extended endoscopic endonasal approach under 3D endoscopic guidance in the intra-operative suite. Safe and effective removal of a supra-diaphragmatic ectopic pituitary adenoma was accomplished via the extended endoscopic endonasal approach with visual information provided by 3D endoscopy and intra-operative MRI.

  14. Systematic Review and Meta-Analysis of Randomized Controlled Trials Evaluating Prophylactic Intra-Operative Wound Irrigation for the Prevention of Surgical Site Infections

    NARCIS (Netherlands)

    de Jonge, Stijn W.; Boldingh, Quirine J. J.; Solomkin, Joseph S.; Allegranzi, Benedetta; Egger, Matthias; Dellinger, E. Patchen; Boermeester, Marja A.

    2017-01-01

    Surgical site infections (SSIs) are one of the most common hospital-acquired infections. To reduce SSIs, prophylactic intra-operative wound irrigation (pIOWI) has been advocated, although the results to date are equivocal. To develop recommendations for the new World Health Organization (WHO) SSI

  15. Expected radiation and radioecological consequences of nuclear heating plant operation

    International Nuclear Information System (INIS)

    Sarkisov, A.A.; Vysotskij, V.L.; Bilashenko, V.P.

    2008-01-01

    Evaluation of the radiation and the radioecological consequences of the operation of the floating NPPs (FNP) constructed to ensure power supply of the remote not easily accessible Far North and Far East regions is a very acute issue. The issue was studied on the basis of the evaluation results of the FNP effect on the personnel, the population and the environment derived by means of the calculation at the stage of the designing efforts, and on the basis of the generalization and the analysis of the records of the naval reactor operation in the northern and the Far East areas [ru

  16. Radiation exposure of patients and operators during interventional radiology

    Energy Technology Data Exchange (ETDEWEB)

    Krahe, T.; Ewen, K.; Lackner, K.; Koester, O.; Nicolas, V.

    1986-08-01

    Surface doses received by patients and operators were measured during 30 interventional radiological procedures (ten percutaneous transhepatic biliary drainages, ten percutaneous nephrostomies, ten percutaneous transluminal angioplasties). In addition, organ doses to the patient were determined using an Alderson-Rando phantom. These served as a basis for calculating the so-called somatic dose indices. It was found that the somatic radiation risk to the patient is relatively small despite prolonged periods of fluoroscopy. However, exposure of the hands and lenses of the operator could easily reach the limits thought acceptable while carrying out these procedures with additional angiography. (orig).

  17. Improving patient selection for selective internal radiation therapy of intra-hepatic cholangiocarcinoma: A meta-regression study.

    Science.gov (United States)

    Cucchetti, Alessandro; Cappelli, Alberta; Mosconi, Cristina; Zhong, Jian-Hong; Cescon, Matteo; Pinna, Antonio D; Golfieri, Rita

    2017-07-01

    Selective internal radiation therapy (SIRT) is emerging as a potential therapy for unresectable intra-hepatic cholangiocarcinoma (iCCA) able to prolong life-expectancy. Aim of this study was to collect available literature meta-analyse data and results and investigate sources of heterogeneity through a meta-regression approach before suggesting SIRT as a valuable option. A systematic review of studies published until 1 September 2016 in PubMed and Scopus databases was performed. Patient survival was the primary outcome measure. Meta-analysis was performed using a random-effects model. Meta-regression was applied to investigate relationships existing between clinical and tumour features and the primary outcome. Nine observational studies were included in the analysis involving 224 patients. The 1-, 2- and 3-year pooled survival estimates were 55.7%, 33.1% and 20.2%. Clinical and tumour characteristics showed medium-to-considerable heterogeneity (I 2 >50%). Meta-regression analysis showed that determinants of best survivals were the presence of mass-forming iCCA type (median survival=19.9 months vs 8.1 months for the infiltrative type; P=.002) that also accounted for most of the heterogeneity between included studies (residual I 2 =0); SIRT as first-line therapy (median survival=24 months vs 11.5 months for non-naïve patients; P=.048) and the adoption of concomitant chemotherapy (median survival 19.5 months vs 5.5 months in patients not receiving chemotherapy; P=.042). There is considerable heterogeneity between studies highlighting that indications for SIRT are extremely varied. To ameliorate SIRT results naïve patients with mass-forming iCCA should be selected as the best candidates with the possibility of adding concomitant standard chemotherapy. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  18. Direct evidence of the left caudate's role in bilingual control: an intra-operative electrical stimulation study.

    Science.gov (United States)

    Wang, Xin; Wang, Yin-Yan; Jiang, Tao; Wang, Yong-Zhi; Wu, Chen-Xing

    2013-01-01

    Bilinguals need control mechanisms in order to switch between languages in different communication contexts (Green, 1998, Bilingualism: Language and Cognition, 1; Price, Green, & von Studnitz, 1999, Brain, 122). There has been neural evidence showing competition to control output in L2 vs. L1 in both cortical and sub-cortical areas, when language selection is carried out (Abutalebi & Green, 2007, Journal of Neurolinguistics, 20). Here we use intra-operative direct electrical stimulation to demonstrate that the head of the left caudate is critical not only in language switching tasks but other control tasks. A bilingual Chinese-English patient was instructed to perform both language switching and switching in color-shape naming tasks during awake glioma surgery. When stimulation was applied on the left caudate, failures or difficulties in both language switching and color-shape naming were observed, with the effects greater on language switching. Stimulation to neighboring brain regions either did not affect performance or generated mild problems specific to language switching. The results provide direct evidence of the necessary role of the left caudate in language control.

  19. Evaluation of Pediatric Liver Transplantation-Related Artery Complications Using Intra-Operative Multi-Parameter Ultrasonography.

    Science.gov (United States)

    Ren, Xiuyun; Guan, Junhui; Gao, Nong; Niu, Hong; Tang, Jie

    2016-11-21

    BACKGROUND This article discusses the value of using multi-parameter evaluation of intra-operative ultrasonography in evaluating pediatric liver transplantation-related arterial complications. MATERIAL AND METHODS Sixty-eight children receiving a liver transplant underwent intraoperative ultrasonography for monitoring of artery hemodynamics. The ultrasonic measurement parameters included the diameters of the hepatic artery (HA) of the donor and anastomotic stoma, peak systolic velocity (PSV), resistance index (RI), acceleration time (SAT), and blood flow volume. RESULTS After being treated immediately using surgery or other means, blood flow returned to normal in 8 cases, and did not in 3 cases, of whom 2 experienced postoperative HAT. There was a significant difference in HA diameter of the donor, anastomotic stoma diameter, PSV, RI, SAT, and blood flow volume before and after treatment of the donor in the complications group. Postoperative complications occurred in 7 of 68 recipients, including the 2 cases exhibiting complications during the surgery (complication group) and 5 without complications during the surgery (no complication group). There was a statistically significant difference (Pultrasonography parameters of HA diameter, anastomotic stoma diameter, RI, and blood flow volume. CONCLUSIONS Through intraoperative multi-parameter ultrasonic measurement, a definite diagnosis of hepatic artery complications can be made in liver transplantation patients. HA diameter of the donor, anastomotic stoma diameter, PSV, RI, SAT, and blood flow volume are important in assessing intraoperative artery complications.

  20. Pain and intra-operative amnesia evaluation with local anesthesia and sedation in patients subjected to rhinosseptoplasties

    Directory of Open Access Journals (Sweden)

    Weber, Raimar

    2010-03-01

    Full Text Available Introduction: The local anesthesia practice and sedation to rhinoplasty and others aesthetics procedures of the face are each time more frequents. In the Brazil, the Federal Council of Medicine defines it and regulate its practice. Objective: To analyze the analgesia' effectiveness and of the intro operative amnesia through analogous visual and subjective scales in the rhinosseptoplasties performed under local anesthesia and sedation, looking for associations with the medium quantities of medication utilized. Method: A retrospective study based in reports relatives to 158 aesthetic-functional rhinoplasties. The surgeon recorded in a protocol the data relatives to the use of local anesthetics and sedatives (including concentration and quantities utilized as well as the side effects. In the first return post surgery the patient quantifies the pain that he felt in the intra operative utilizing a analogous visual scale as described by Hasen and collaborators. The Amnesia considered ideal when the patient referred to remind "nothing" or "a few of the procedure. Results: The sample constituted of 80 (73,4% women and 29 26,6% men, average of age of 29,3 ± 9,5 years. The median of the pain by the analogous visual scale was 0,05; 80% under 3,35. The amnesia was ideal in 51 (46,8% surgeries. The midazolam was utilized in all the surgeries. Fentanyl in 32 (29,4% and, pethidine in 77 (70,6%. Had not statistically significants differences between the quantities of medication utilized between the groups of patients with ideal amnesia when compared with those that do not obtained satisfactory amnesia. Conclusion: Local anesthesia and sedation in rhinoplasties are comfortable and secures in the majority of the cases, even without have a satisfactory amnesia.

  1. Is intra-operative cholangiography necessary during laparoscopic cholecystectomy? A multicentre rural experience from a developing world country.

    Science.gov (United States)

    Mir, Iqbal Saleem; Mohsin, Mir; Kirmani, Omar; Majid, Tafazul; Wani, Khurshid; Hassan, Mehmood-Ul; Naqshbandi, Javed; Maqbool, Mohammed

    2007-09-07

    To evaluate the feasibility and safety of performing laparoscopic cholecystectomy (LC) in non-teaching rural hospitals of a developing country without intra-operative cholangiography (IOC). To evaluate the possibility of reduction of costs and hospital stay for patients undergoing LC. A prospective analysis of patients with symptomatic benign diseases of gall bladder undergoing LC in three non-teaching rural hospitals of Kashmir Valley from Jan 2001 to Jan 2007. The cohort represented a sample of patients requiring LC, aged 13 to 78 (mean 47.2) years. Main outcome parameters included mortality, complications, re-operation, conversion to open procedure without resorting to IOC, reduction in costs borne by the hospital, and the duration of hospital stay. Twelve hundred and sixty-seven patients (976 females/291 males) underwent laparoscopic cholecystectomy. Twenty-three cases were converted to open procedures; 12 patients developed port site infection, nobody died because of the procedure. One patient had common bile duct (CBD) injury, 4 patients had biliary leak, and 4 patients had subcutaneous emphysema. One cholecystohepatic duct was detected and managed intraoperatively, 1 patient had retained CBD stones, while 1 patient had retained cystic duct stones. Incidental gallbladder malignancy was detected in 2 cases. No long-term complications were detected up to now. LC can be performed safely even in non-teaching rural hospitals of a developing country provided proper equipment is available and the surgeons and other team members are well trained in the procedure. It is stressed that IOC is not essential to prevent biliary tract injuries and missed CBD stones. The costs to the patient and the hospital can be minimized by using reusable instruments, intracorporeal sutures, and condoms instead of titanium clips and endobags.

  2. Operation of an industrial radiation processing facility in Mexico

    Science.gov (United States)

    Torres C., Gilberto

    A 10 years old JS-6500 industrial Cobalt 60 irradiator was installed in 1980 at the ININ Nuclear Center in Mexico with 960 kGy. The facility was commissioning in August with some minor changes with respect to the original AECL design, in order to give services to different industries and also to do research in several fields. During that year promotional activities were done to increase interest from industry in the use of radiation processing. In 1981, an interruption due to pool's leakage and its reparation, put the facility out of operation. During the next three years the demand increases but never reach more than 50% if the capacity. In that time, the potential users did not show confidence in the process, even knowing that health authorities approved with no restrictions radiation sterilization. Actually, there are 34 different companies irradiating 48 different products. Even those within the same grouping, require different minimum and maximum radiation doses, so the facility has been operated combining products and valumes. The experiences are presented in this paper. Also, maintenance of the irradiator is discussed and some modifications to the original programme have been done due to the necessity to use local spare parts instead of imported ones.

  3. Radiation protection problems by the operation of the cyclotron facility

    International Nuclear Information System (INIS)

    Durcik, M.; Nikodemova, D.

    1998-01-01

    The Cyclotron Center in Bratislava will consist of two cyclotrons. First - cyclotron DC-72 with maximal energy of 72 MV for protons for making experiments, for teaching process, for radioisotope production as 123 I and for neutron and proton therapy. Second - compact cyclotron with maximal proton energy of 18 MeV will be used for radioisotopes production for medical diagnosis as 1 *F (fluorodeoxyglucose), 81 Rb/ 81 Kr generator. This paper deals with the radiation protection problems by the operation of tis cyclotron facility as radiation protection of workers, monitoring plan, ventilation, safety lock and limitation and radiation monitoring. For proposed and continuing practices at the accelerator facility, the following general principles have to be fulfilled: (1) practices should produce sufficient benefit to offset the radiation detriment they case (justification); (2) the magnitude of the individual doses should be kept as low as achievable (optimization of protection); (3) individual exposures are subject to dose limits and some control of risk from potential exposures (dose and risk limits)

  4. Intra-Operative Surgical Irrigation of the Surgical Incision: What Does the Future Hold-Saline, Antibiotic Agents, or Antiseptic Agents?

    Science.gov (United States)

    Edmiston, Charles E; Leaper, David J

    2016-12-01

    Intra-operative surgical site irrigation (lavage) is common practice in surgical procedures in general, with all disciplines advocating some form of irrigation before incision closure. This practice, however, has been neither standardized nor is there compelling evidence that it effectively reduces the risk of surgical site infection (SSI). This narrative review addresses the laboratory and clinical evidence that is available to support the practice of irrigation of the abdominal cavity and superficial/deep incisional tissues, using specific irrigation solutions at the end of an operative procedure to reduce the microbial burden at wound closure. Review of PubMed and OVID for pertinent, scientific, and clinical publications in the English language was performed. Incision irrigation was found to afford a three-fold benefit: First, to hydrate the bed; second, to assist in allowing better examination of the area immediately before closure; and finally, by removing superficial and deep incisional contamination and lowering the bioburden, expedite the healing process. The clinical practice of intra-operative peritoneal lavage is highly variable and is dependent solely on surgeon preference. By contrast, intra-operative irrigation after device-related procedures has become a standard of care for the prophylaxis of acute peri-prosthetic infection. The clinical evidence that supports the use of antibiotic irrigation is limited and based on retrospective analysis and few acceptable randomized controlled trials. The results of laboratory and animal studies using aqueous 0.05% chlorhexidine gluconate are favorable, suggesting that further studies are justified to determine its clinical efficacy. The adoption of appropriate and standardized intra-operative irrigation practices into peri-operative care bundles, which include other evidence-based strategies (weight-based antimicrobial prophylaxis, antimicrobial sutures, maintenance of normothermia, and glycemic control), offers

  5. radiation safety culture for developing country: Basis for s minimum operational radiation protection programme

    International Nuclear Information System (INIS)

    Rozental, J. J.

    1997-01-01

    The purpose of this document is to present a methodology for an integrated strategy aiming at establishing an adequate radiation Safety infrastructure for developing countries, non major power reactor programme. Its implementation will allow these countries, about 50% of the IAEA's Member States, to improve marginal radiation safety, specially to those recipients of technical assistance and do not meet the Minimum radiation Safety Requirements of the IAEA's Basic Safety Standards for radiation protection Progress in the implementation of safety regulations depends on the priority of the government and its understanding and conviction about the basic requirements for protection against the risks associated with exposure to ionizing radiation. There is no doubt to conclude that the reasons for the deficiency of sources control and dose limitation are related to the lack of an appropriate legal and regulatory framework, specially considering the establishment of an adequate legislation; A minimum legal infrastructure; A minimum operational radiation safety programme; Alternatives for a Point of Optimum Contact, to avoid overlap and conflict, that is: A 'Memorandum of Understanding' among Regulatory Authorities in the Country, dealing with similar type of licensing and inspection

  6. Adjuvant radiation therapy versus surgery alone in operable breast cancer

    International Nuclear Information System (INIS)

    Rutqvist, L.E.; Pettersson, D.; Johansson, H.

    1993-01-01

    This paper presents long-term results from a randomized trial of pre- or postoperative megavoltage radiation therapy versus surgery alone in pre- and postmenopausal women with operable breast cancer. Treatment outcome after relapse among patients who developed loco-regional recurrences was also analyzed. A total of 960 patients were included in the trial. The mean follow-up was 16 years (range: 13-19 years). The radiation therapy was individually planned. It included the chest wall (and the breast in the preoperative cases) and the regional lymph nodes. The tumor dose was 45 Gy/5 weeks. No adjuvant systemic therapy was used. The results showed a significant benefit with radiation therapy in terms of recurrence-free survival during the entire follow-up period. There was also an overall survival difference - corresponding to 16% reduction of deaths - in favour of the irradiated patients which, however, was not statistically significant (p=0.09). Among those 169 patients who developed loco-regional recurrences long-term control was only achieved in about one-third of the cases. This figure was similar among those who had received adjuvant radiation therapy (34%) compared to those initially treated with surgery alone (32%). This implied that the overall proportion of patients who eventually developed uncontrolled local disease was significantly higher among those initially allocated to surgery alone (16%) compared to those allocated to pre- or postoperative radiation therapy (6%, p<0.01). These results suggest that local undertreatment may be deleterious in subgroups of patients. (author) 5 tabs

  7. Uso do 5-fluorouracil no intra-operatório da cirurgia do pterígio Intra-operative use of 5-fluorouracil in pterygium surgery

    Directory of Open Access Journals (Sweden)

    Silvana A. Schellini

    2000-04-01

    Full Text Available Objetivo: Avaliar a efetividade e as complicações com a aplicação do 5- fluorouracil (5-FLU no intra-operatório da cirurgia do pterígio. Método: Foram avaliados 28 olhos de 26 indivíduos quanto ao tipo e tamanho do pterígio, cirurgias prévias e a resposta ao tratamento cirúrgico (no 7º , 21º , 60º e 90º dia de pós-operatório. Logo após a exerese do pterígio, aplicou-se 5-FLU (25 mg/ml no leito cirúrgico, durante cinco minutos; a seguir, realizou-se a técnica de deslizamento de retalho conjuntival. Resultados: A maioria dos pacientes tinha mais de 50 anos de idade e apresentava pterígio primário (70,0%, grau II (60,7%, do tipo involutivo (60,7%. No pós-operatório observaram-se: isquemia (10,7%, deiscência da conjuntiva (7,1%, ceratite (3,5%, conjuntivite (3,5% e recidiva da lesão em 1 olho (3,5%.Conclusão: O 5-FLU se mostrou droga segura e efetiva na prevenção das recidivas, podendo ser usado como coadjuvante no tratamento do pterígio para prevenir recidivas.Purpose: To evaluate the effectiveness and the complications on intraoperative application of 5-fluorouracil (5FLU in pterygium surgery. Method: We studied 28 eyes of 26 patients with pterygium, evaluating the type and size of the pterygium, previous surgeries and the response to surgical treatment (on the 7th, 21st, 60th, 90th postoperative day. The application of 5-FLU (25 mg/ml was done soon after resection, for five minutes, followed by the sliding flap technique.Results: Most of the patients were more than 50 years old, presented with primary (70.0%, degree II (60.7%, involu-tionary type (60.7% pterygium. After surgery ischemic area (10.7%, conjunctival deiscence (7.1%, keratitis (3.5%, conjunctivitis (3.5% and lesion relapse (3.5% were observed.Conclusion: 5-FLU is a safe and effective drug and could be of help in the treatment of pterygium to prevent relapse.

  8. Intra-operative wound irrigation to reduce surgical site infections after abdominal surgery: a systematic review and meta-analysis.

    Science.gov (United States)

    Mueller, Tara C; Loos, Martin; Haller, Bernhard; Mihaljevic, André L; Nitsche, Ulrich; Wilhelm, Dirk; Friess, Helmut; Kleeff, Jörg; Bader, Franz G

    2015-02-01

    Surgical site infection (SSI) remains to be one of the most frequent infectious complications following abdominal surgery. Prophylactic intra-operative wound irrigation (IOWI) before skin closure has been proposed to reduce bacterial wound contamination and the risk of SSI. However, current recommendations on its use are conflicting especially concerning antibiotic and antiseptic solutions because of their potential tissue toxicity and enhancement of bacterial drug resistances. To analyze the existing evidence for the effect of IOWI with topical antibiotics, povidone-iodine (PVP-I) solutions or saline on the incidence of SSI following open abdominal surgery, a systematic review and meta-analysis of randomized controlled trials (RCTs) was carried out according to the recommendations of the Cochrane Collaboration. Forty-one RCTs reporting primary data of over 9000 patients were analyzed. Meta-analysis on the effect of IOWI with any solution compared to no irrigation revealed a significant benefit in the reduction of SSI rates (OR = 0.54, 95 % confidence Interval (CI) [0.42; 0.69], p < 0.0001). Subgroup analyses showed that this effect was strongest in colorectal surgery and that IOWI with antibiotic solutions had a stronger effect than irrigation with PVP-I or saline. However, all of the included trials were at considerable risk of bias according to the quality assessment. These results suggest that IOWI before skin closure represents a pragmatic and economical approach to reduce postoperative SSI after abdominal surgery and that antibiotic solutions seem to be more effective than PVP-I solutions or simple saline, and it might be worth to re-evaluate their use for specific indications.

  9. Radiation safety for operators of gamma irradiation plants

    International Nuclear Information System (INIS)

    1989-01-01

    These notes have been prepared by the UK Panel for Gamma and Electron Irradiation with advice from the HSE (Technology Division and Factory and Agricultural Inspectorate) to assist operators of Gamma irradiation plants to comply with the requirements of the Ionising Radiations Regulations (IRR 1985), and other relevant regulations (see below). The process is currently used for the sterilisation of medical devices and in the treatment of plastics materials etc. The Government has proposed that the process should also be permitted for the treatment of foodstuffs, and these notes will also be relevant to any irradiation plants which may be used in the UK for this purpose. (author)

  10. Fracture Surgery of the extremities with the intra-operative use of 3D-RX: A randomized multicenter trial (EF3X-trial

    Directory of Open Access Journals (Sweden)

    Marmor Meir

    2011-07-01

    Full Text Available Abstract Background Posttraumatic osteoarthritis can develop after an intra-articular extremity fracture, leading to pain and loss of function. According to international guidelines, anatomical reduction and fixation are the basis for an optimal functional result. In order to achieve this during fracture surgery, an optimal view on the position of the bone fragments and fixation material is a necessity. The currently used 2D-fluoroscopy does not provide sufficient insight, in particular in cases with complex anatomy or subtle injury, and even an 18-26% suboptimal fracture reduction is reported for the ankle and foot. More intra-operative information is therefore needed. Recently the 3D-RX-system was developed, which provides conventional 2D-fluoroscopic images as well as a 3D-reconstruction of bony structures. This modality provides more information, which consequently leads to extra corrections in 18-30% of the fracture operations. However, the effect of the extra corrections on the quality of the anatomical fracture reduction and fixation as well as on patient relevant outcomes has never been investigated. The objective of this study protocol is to investigate the effectiveness of the intra-operative use of the 3D-RX-system as compared to the conventional 2D-fluoroscopy in patients with traumatic intra-articular fractures of the wrist, ankle and calcaneus. The effectiveness will be assessed in two different areas: 1 the quality of fracture reduction and fixation, based on the current golden standard, Computed Tomography. 2 The patient-relevant outcomes like functional outcome range of motion and pain. In addition, the diagnostic accuracy of the 3D-RX-scan will be determined in a clinical setting and a cost-effectiveness as well as a cost-utility analysis will be performed. Methods/design In this protocol for an international multicenter randomized clinical trial, adult patients (age > 17 years with a traumatic intra-articular fracture of the

  11. Radiation protection issues after 20 years of LHC operation

    CERN Document Server

    Forkel-Wirth, D.; Roesler, S.; Theis, C.; Ulrici, L.; Vincke, H.; Vincke, Hz.

    2011-01-01

    Since November 2009, the LHC commissioning progresses very well, both with proton and lead beams. It will continue in 2011 and nominal LHC operation is expected to be attained in 2013. In parallel, plans for various LHC upgrades are under discussion, suggesting a High-Luminosity (HL) upgrade first and a High-Energy (HE) upgrade in a later state. Whereas the upgrade in luminosity would require the modification of only some few key accelerator components like the inner triplets, the upgrade in beam energy from 7 TeV to 16.5 TeV would require the exchange of all dipoles and of numerous other accelerator components. The paper gives an overview of the radiation protection issues related to the dismantling of LHC components prior to the installation of the HE-LHC components, i.e. after about 20 years of LHC operation. Two main topics will be discussed: (i) the exposure of workers to ionizing radiation during the dismantling of dipoles, inner triplets or collimators and experiments and (ii) the production, condition...

  12. Frozen section is superior to imprint cytology for the intra-operative assessment of sentinel lymph node metastasis in Stage I Breast cancer patients

    Directory of Open Access Journals (Sweden)

    Makita Masujiro

    2006-05-01

    Full Text Available Abstract Background A standard intra-operative procedure for assessing sentinel lymph node metastasis in breast cancer patients has not yet been established. Patients and methods One hundred and thirty-eight patients with stage I breast cancer who underwent sentinel node biopsy using both imprint cytology and frozen section were analyzed. Results Seventeen of the 138 patients had sentinel node involvement. Results of imprint cytology included nine false negative cases (sensitivity, 47.1%. In contrast, only two cases of false negatives were found on frozen section (sensitivity, 88.2%. There were two false positive cases identified by imprint cytology (specificity, 98.3%. On the other hand, frozen section had 100% specificity. Conclusion These findings suggest that frozen section is superior to imprint cytology for the intra-operative determination of sentinel lymph node metastasis in stage I breast cancer patients.

  13. Ionizing radiation exposure in interventional cardiology: current radiation protection practice of invasive cardiology operators in Lithuania.

    Science.gov (United States)

    Valuckiene, Zivile; Jurenas, Martynas; Cibulskaite, Inga

    2016-09-01

    Ionizing radiation management is among the most important safety issues in interventional cardiology. Multiple radiation protection measures allow the minimization of x-ray exposure during interventional procedures. Our purpose was to assess the utilization and effectiveness of radiation protection and optimization techniques among interventional cardiologists in Lithuania. Interventional cardiologists of five cardiac centres were interviewed by anonymized questionnaire, addressing personal use of protective garments, shielding, table/detector positioning, frame rate (FR), resolution, field of view adjustment and collimation. Effective patient doses were compared between operators who work with and without x-ray optimization. Thirty one (68.9%) out of 45 Lithuanian interventional cardiologists participated in the survey. Protective aprons were universally used, but not the thyroid collars; 35.5% (n  =  11) operators use protective eyewear and 12.9% (n  =  4) wear radio-protective caps; 83.9% (n  =  26) use overhanging shields, 58.1% (n  =  18)-portable barriers; 12.9% (n  =  4)-abdominal patient's shielding; 35.5% (n  =  11) work at a high table position; 87.1% (n  =  27) keep an image intensifier/receiver close to the patient; 58.1% (n  =  18) reduce the fluoroscopy FR; 6.5% (n  =  2) reduce the fluoro image detail resolution; 83.9% (n  =  26) use a 'store fluoro' option; 41.9% (N  =  13) reduce magnification for catheter transit; 51.6% (n  =  16) limit image magnification; and 35.5% (n  =  11) use image collimation. Median effective patient doses were significantly lower with x-ray optimization techniques in both diagnostic and therapeutic interventions. Many of the ionizing radiation exposure reduction tools and techniques are underused by a considerable proportion of interventional cardiology operators. The application of basic radiation protection tools and

  14. Study of four cases of radiation colitis needed operation therapy

    International Nuclear Information System (INIS)

    Sasaki, Shigeru; Takesue, Yoshio; Yokoyama, Takashi

    1996-01-01

    On the 4 cases of operation for the late radiation effect, the process and notes for radiation colitis were described. Case 1; a female of 57 y with cervical carcinoma (IIIb) received 59.8 Gy of external irradiation and 24.0 Gy of intracervical irradiation. About 8 months after the radiotherapy, anemia due to gut bleeding was observed and hemorrhage was seen in the colon with the colon fiber. One year later, colostomy was performed. Case 2; a female of 79 y with cervical carcinoma (IIb) received 50.0 Gy of external irradiation and 18.0 Gy of intracervical irradiation. About 8 months after the therapy, gut bleeding and ileac symptom were observed and ulcer and stenosis in the sigmoid colon were seen. Sigmoidectomy was performed. Case 3; a female of 75 y with cervical carcinoma (IIIb) received external 49.8 Gy irradiation and intracervical 23.0 Gy irradiation. About 4 months after the therapy, anemia and ulcer with hemorrhage in the sigmoidal colon were recognized. Sigmoidectomy and colostomy were performed. Case 4; a female of 68 y with cervical carcinoma (IIb) and chronic renal failure received 50.4 Gy of external irradiation post hysterectomy. About 5 months later, iliac symptom was observed. She received ileectomy and then colostomy but died of MOF due to renal failure. (K.H.)

  15. The ALICE Transition Radiation Detector: Construction, operation, and performance

    Science.gov (United States)

    Alice Collaboration

    2018-02-01

    The Transition Radiation Detector (TRD) was designed and built to enhance the capabilities of the ALICE detector at the Large Hadron Collider (LHC). While aimed at providing electron identification and triggering, the TRD also contributes significantly to the track reconstruction and calibration in the central barrel of ALICE. In this paper the design, construction, operation, and performance of this detector are discussed. A pion rejection factor of up to 410 is achieved at a momentum of 1 GeV/ c in p-Pb collisions and the resolution at high transverse momentum improves by about 40% when including the TRD information in track reconstruction. The triggering capability is demonstrated both for jet, light nuclei, and electron selection.

  16. Diamond Ordinance Radiation Facility (DORF) reactor operating experiences

    International Nuclear Information System (INIS)

    Gieseler, Walter

    1970-01-01

    The Diamond Ordnance Radiation Facility Mark F Reactor is described and some of the problems encountered with its operation are discussed. In a period from reactor startup in September 1961 to June 1964, when the aluminum-clad core was changed to a stainless-steel clad core, a total of 30 fuel elements were removed from reactor service because of excessive growth. One leaking fuel element was detected during the lifetime of the aluminum- clad core. In June 1964, the core was changed to the stainless-steel-clad high hydride fuel elements. Since the installation of the stainless-steel-clad fuel element core, there has been a gradual decline of excess reactivity. Various theories were discussed as the cause but the investigations have resulted in no definitive conclusion that could account for the total reactivity loss

  17. Radiation dosimetry for crewmember exposure to cosmic radiation during astronaut training operations

    International Nuclear Information System (INIS)

    Shavers, M.R.; Gersey, B.B.; Wilkins, R.T.; Semones, E.J.; Cucinotta, F.A.

    2003-01-01

    'Atmospheric exposures' of astronauts to cosmic ions and secondary particles during air-flight training are being measured and analytically modeled for inclusion in the astronaut medical records database. For many of the ∼170 astronauts currently in the astronaut corps, their occupational radiation exposure history will be dominated by cosmic ion exposures during air-travel rather than short-duration spaceflight. Relatively low (usually <10 μSv hr -1 ) and uniform organ dose rates result from the penetrating mix of cosmic particles during atmospheric exposures at all altitudes, but at rates that vary greatly due to differences in flight profiles and the geomagnetic conditions at the time of flight. The precision and accuracy to which possible deleterious effects of the exposures can be assessed suffers from limitations that similarly impact assessment of human exposures in low-Earth orbit: uncertainties associated with the environmental measurements and their interpretation, uncertainties associated with the analytical tools that transport the cosmic radiation environment, and uncertain biological responses to low-dose-rate exposures to radiation fields of mixed radiation 'quality'. Lineal energy spectra will be measured using a Tissue Equivalent Proportional Counter designed for training and operational sorties frequently flown in T-38, Space Shuttle Trainer, and high altitude WB-57 aircraft. Linear energy spectra will be measured over multiple flights using CR-39 plastic nuclear track detectors, as well. Flight records are available for nearly 200,000 sorties flown in NASA aircraft by astronauts and flight officers in the Johnson Space Center Aircraft Operations Division over the past 25 years, yet this database only partially documents the complete exposure histories. Age-dependent risk analysis indicates significant impact, particularly to young women who anticipate lengthy on-orbit careers

  18. Comparison of intra-articular bupivacaine-morphine with bupivacaine-tenoxicam combinations on post-operative analgesia in patients with arthroscopic meniscectomy: a prospective, randomised study.

    Science.gov (United States)

    Sanel, Selim; Arpaz, Osman; Unay, Koray; Turkmen, Ismail; Simsek, Selcuk; Ugutmen, Ender

    2016-03-01

    There are many alternatives for post-operative pain relief in patients who have had general anaesthesia. The aim of this study was to evaluate the efficacy of intra-articular bupivacaine + morphine and bupivacaine + tenoxicam applications in post-operative pain control in patients undergoing knee arthroscopy with general anaesthesia. This was a prospective study. Standard anaesthesia procedures were applied to each patient, and the 240 patients chosen at random were then divided into two groups. Each group received a different combination of drugs for this double-blind study. The first group (group A: 120 patients) received 0.5% bupivacaine 100 mg + tenoxicam 20 mg (22 ml); the second group (group B) received 0.5% bupivacaine 100 mg + morphine 2 mg (22 ml); both groups received their drugs at the end of the intra-articular operation before tourniquet deflation. Before the operation, patients were asked about their post-operative pain at particular periods over the following 24 hours using the visual analogue scale (VAS) and the numeric rating scale (NRS). An additional analgaesic requirement and possible side effects were also recorded. Group A patients needed analgaesics sooner after operation than patients in group B. In Group B, VAS and NRS values were statistically higher compared with group A at the 12th hour. There were also fewer side effects seen in group A versus group B. Effective and reliable results were obtained in post-operative pain control in bupivacaine added to the morphine or tenoxicam groups following arthroscopic meniscectomy. In the tenoxicam group, patients reported less pain, fewer side effects and less need for analgesics at 12 hours after the operation. level 1, therapeutic, randomised, multicentric study.

  19. Atmospheric Radiation Measurement program climate research facility operations quarterly report.

    Energy Technology Data Exchange (ETDEWEB)

    Sisterson, D. L.; Decision and Information Sciences

    2006-09-06

    Individual raw data streams from instrumentation at the Atmospheric Radiation Measurement (ARM) Program Climate Research Facility (ACRF) fixed and mobile sites are collected and sent to the Data Management Facility (DMF) at Pacific Northwest National Laboratory (PNNL) for processing in near real time. Raw and processed data are then sent daily to the ACRF Archive, where they are made available to users. For each instrument, we calculate the ratio of the actual number of data records received daily at the Archive to the expected number of data records. The results are tabulated by (1) individual data stream, site, and month for the current year and (2) site and fiscal year dating back to 1998. The U.S. Department of Energy requires national user facilities to report time-based operating data. The requirements concern the actual hours of operation (ACTUAL); the estimated maximum operation or uptime goal (OPSMAX), which accounts for planned downtime; and the VARIANCE [1-(ACTUAL/OPSMAX)], which accounts for unplanned downtime. The OPSMAX time for the third quarter for the Southern Great Plains (SGP) site is 2,074.80 hours (0.95 x 2,184 hours this quarter). The OPSMAX for the North Slope Alaska (NSA) locale is 1,965.60 hours (0.90 x 2,184), and that for the Tropical Western Pacific (TWP) locale is 1,856.40 hours (0.85 x 2,184). The OPSMAX time for the ARM Mobile Facility (AMF) is 2,074.80 hours (0.95 x 2,184). The differences in OPSMAX performance reflect the complexity of local logistics and the frequency of extreme weather events. It is impractical to measure OPSMAX for each instrument or data stream. Data availability reported here refers to the average of the individual, continuous data streams that have been received by the Archive. Data not at the Archive are caused by downtime (scheduled or unplanned) of the individual instruments. Therefore, data availability is directly related to individual instrument uptime. Thus, the average percent of data in the Archive

  20. Sublingual misoprostol is as effective as intravenous oxytocin to reduce intra-operative blood loss during cesarean delivery in women living at high altitude.

    Science.gov (United States)

    Gavilanes, Patricio; Morales, Maria Fernanda; Velasco, Stiward; Teran, Enrique

    2016-01-01

    To assess the effect of sublingual misoprostol compared to intravenous oxytocin for blood loss during cesarean delivery in women living at high altitude. In a randomized trial, conducted in Quito, Ecuador (2800 m above sea level), 100 women received either sublingual misoprostol (400 µg) or intravenous oxytocin (10 IU). Bleeding in the misoprostol was no different than in the oxytocin group. Shivering was reported in 66% of women in the misoprostol group. Sublingual misoprostol might be a valid alternative to oxytocin reduce intra-operative blood loss during cesarean section in women living at high altitude.

  1. Effects of intra-operative end-tidal carbon dioxide levels on the rates of post-operative complications in adults undergoing general anesthesia for percutaneous nephrolithotomy: A clinical trial

    Directory of Open Access Journals (Sweden)

    Mahmoud Saghaei

    2014-01-01

    Full Text Available Background: A retrospective study has shown lesser days of hospital stay in patients with increased levels of intra-operative end-tidal carbon dioxide (ETCO 2 . It is probable that hypercapnia may exert its beneficial effects on patients′ outcome through optimization of global hemodynamic and tissue oxygenation, leading to a lower rate of post-operative complications. This study was designed to test the hypothesis that higher values of intra-operative ETCO 2 decrease the rate of post-operative complications. Materials and Methods: In this randomized, double-blind clinical trial, 78 adult patients scheduled for percutaneous nephrolithotomy (PCNL were prospectively enrolled and randomly divided into three groups. ETCO 2 was set and maintained throughout the procedure at 31-33, 37-39 and 43-45 mmHg in the hypocapnia, normocapnia and hypercapnia groups, respectively. The rates of post-operative complications were compared among the three groups. Results: Seventy-five patients completed the study (52 male and 23 female. Ten (38.5%, four (16% and two (8.3% patients developed post-operative vomiting in the hypocapnia, normocapnia and hypercapnia groups, respectively (P = 0.025. The nausea score was significantly lower in the hypercapnic group compared with the other groups (3.9 ± 1.8, 3.2 ± 2.1 and 1.3 ± 1.8 in the hypocapnia, normocapnia and hypercapnia groups, respectively; P = 0.000. Time to return of spontaneous respiration and awakening were significantly decreased in the hypercapnia group compared with the other groups (P < 0.01. Conclusion: Mild intra-operative hypercapnia has a protecting effect against the development of post-operative nausea and vomiting and decreases the duration of emergence and recovery from general anesthesia.

  2. Intra-arterial cisplatin and concurrent radiation in the treatment of invasive bladder cancer in the elderly: 10 years of experience

    International Nuclear Information System (INIS)

    Eapen, L.; Stewart, D.; Grimard, L.; Crook, J.; Aref, I.; Huan, S.; Futter, N.; Rasuli, P.; Peterson, R.

    1998-01-01

    Analysis of the results obtained in elderly (75 years and older) included a phase II trial combining intra-arterial cisplatin and concurrent radiation into invasive bladder cancer. Thirty-five patients (28 males and 7 females) were accrued from 1985 to 1996. There were 1 Ta, 4 T2, 11 T3A, 12 T3B, 3 T4A, and 4 T4B patients. Nine had unilateral hydronephrosis and two bilateral hydronephrosis. There were 28 trans-urethral resections which were incomplete in 23 patients. Intra-arterial cisplatin was given as 2-4 hours infusion (60-90 mg/m 2 ) split through both internal iliac arteries on day 1, 14, 21, and 42. Irradiation to the pelvis was started on day 14 and consisted of 40 Gy/20 fractions followed by a boost of 20 Gy/10 fractions to the tumor with margins of 2 cm. Thirty (86%) completed fully the protocol. One patient died from sepsis secondary to the treatment. The tumor response was evaluable in 29 patients and complete response was observed for 27> of them. Five of these 27 patients had an isolated bladder relapse which was salvaged by by cystectomy in two patients. There were 11 deaths from bladder cancer (31% of the patients): 9 from deaths metastases, one from local failure, and one from treatment. This combined modality yields excellent results with high complete response rate and good tolerance. This approach may therefore be particularly appropriate for the elderly. (author)

  3. Spectroscopic study of radiative intra-configurational 4f→4f transitions in Yb{sup 3+}-doped materials using high hydrostatic pressure

    Energy Technology Data Exchange (ETDEWEB)

    Kaminska, A., E-mail: kaminska@ifpan.edu.pl [Institute of Physics, Polish Academy of Sciences, al. Lotników 32/46, 02-668 Warsaw (Poland); Kozanecki, A. [Institute of Physics, Polish Academy of Sciences, al. Lotników 32/46, 02-668 Warsaw (Poland); Ramirez, M.O.; Bausa, L.E. [Departamento de Fisica de Materiales and Instituto Nicolas Cabrera, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid (Spain); Boulon, G. [Institute Light Matter (ILM), UMR5306 CNRS-University Lyon1, University of Lyon, 69622 Villeurbanne (France); Bettinelli, M. [Luminescent Materials Laboratory, DB, University of Verona and INSTM, UdR Verona, Ca' Vignal, Strada Le Grazie 15, 37134 Verona (Italy); Boćkowski, M. [Institute of High Pressures Physics ‘Unipress’, Polish Academy of Sciences, 01-142 Warsaw (Poland); Suchocki, A. [Institute of Physics, Polish Academy of Sciences, al. Lotników 32/46, 02-668 Warsaw (Poland)

    2016-01-15

    The influence of the hydrostatic pressure on the radiative intra-configurational 4f→4f transitions of several Yb{sup 3+} ions doped dielectrics and semiconductors with different energy gaps and crystal structures is presented. A thorough analysis of ambient pressure spectra and the pressure behavior of the Yb{sup 3+} luminescence lines in InP, GaN, LiNbO{sub 3}, YPO{sub 4}, GdPO{sub 4} and Gd{sub 3}Ga{sub 5}O{sub 12} allowed to determine the ambient pressure and pressure dependence of the Yb{sup 3+} energy level positions in crystal fields of different symmetries. The comparison of the Yb{sup 3+} luminescence decay times in different crystal hosts and their pressure dependencies have also been carried out. The results revealed the significant effect of interaction between the band states and the dopant states, as well as the local symmetry of ytterbium dopant on its radiative transition rate, a relevant parameter when considering the potential applications of ytterbium as optically active ion in different crystal hosts. - Highlights: • We the pressure dependence of spectroscopic properties of Yb{sup 3+} dopant in various crystal matrices. • Energies of f–f transitions of Yb{sup 3+} ions are weakly dependent on the applied pressure. • The influence of pressure on transition probabilities is very pronounced. • The ytterbium dopant symmetry and band-gap energy of host crystal influences significantly the radiative transition rate.

  4. Measures of radiation protection in the operation of nuclear power plants in the German Democratic Republic

    International Nuclear Information System (INIS)

    Richter, D.; Schreiter, W.

    1975-11-01

    A survey is given on the provisions concerning (a) radiation protection at nuclear power plants in the GDR including the instructions applying within the plant, (b) the organization of radiation protection services, and (c) the measures of radiation protection surveillance inside and outside the plant during operation. (author)

  5. Radiation protection for human interplanetary spaceflight and planetary surface operations

    Energy Technology Data Exchange (ETDEWEB)

    Clark, B.C. [Armed Forces Radiobiology Research Inst., Bethesda, MD (United States)]|[DLR Inst. of Aerospace Medicine, Cologne (Germany)]|[NASA, Goddard Space Flight Center, Greenbelt, MD (United States)

    1993-12-31

    Radiation protection issues are reviewed for five categories of radiation exposure during human missions to the moon and Mars: trapped radiation belts, galactic cosmic rays, solar flare particle events, planetary surface emissions, and on-board radiation sources. Relative hazards are dependent upon spacecraft and vehicle configurations, flight trajectories, human susceptibility, shielding effectiveness, monitoring and warning systems, and other factors. Crew cabins, interplanetary mission modules, surface habitats, planetary rovers, and extravehicular mobility units (spacesuits) provide various degrees of protection. Countermeasures that may be taken are reviewed relative to added complexity and risks that they could entail, with suggestions for future research and analysis.

  6. Guide for the monitoring of radiation protection during national modification and maintenance operations. Report nr 307

    International Nuclear Information System (INIS)

    Bataille, C.; Michelet, M.; Schieber, C.

    2010-02-01

    This methodological guide aims at helping the different involved actors in designing and implementing the monitoring of radiation protection during modification and maintenance operations performed at the national level. It describes actions to be performed by each actor in order to comply with the objectives of the four steps related to the radiation protection monitoring of an operation: the design of the radiation protection monitoring during the study phase, the adaptation of this monitoring to the concerned CNPE (electricity production nuclear centre), the radiation protection monitoring during the operation performance, and the analysis of the return on experience

  7. Development and Implementation of Universal Cloud/Radiation Parameterizations in Navy Operational Forecast Models

    Science.gov (United States)

    2013-09-30

    www.eas.purdue.edu/research/clew/index.html LONG-TERM GOALS Improve the simulation of atmospheric radiation energy fields in Navy operational weather...parameters to RRTMG whereas Figures 5 through 12 show the output shortwave and longwave radiation fluxes and cooling rates. Results are identical to... Radiation Parameterizations in Navy Operational Forecast Models Harshvardhan Dept. of Earth, Atmospheric & Planetary Sciences Purdue University West

  8. Preoperative radiation therapy and pelvic autonomic nerve-preserving operation for rectal carcinoma; Especially regarding preoperative radiation therapy

    Energy Technology Data Exchange (ETDEWEB)

    Sarashina, Hiromi; Saito, Norio; Nunomura, Masao (Chiba Univ. (Japan). School of Medicine) (and others)

    1992-12-01

    Results of pelvic plexus nerves and/or hypogastric nerves-preserving operation in combination with preoperative radiation for advanced rectal cancer were examined. Roentogenographically, preoperative radiation had marked effect on the reduction of tumor volume, which was closely related to histological effect. Histologically, high risk factors of local recurrence, such as depth of invasion, ew (defined as the distance between the external surgical surface and the deepest site of invasion) and lymph nodal involvement, have been successfully changed after radiation therapy. Especially, cases in which tumor was limited to within mucosa and proper muscle but not exposed on to the serosal surface did not show positive lymph nodes in the lateral side of the pelvic cavity. These findings suggested that autonomic nerve preserving operation should be undertaken in such cases that demonstrated marked tumor reduction after preoperative radiation therapy. The present study also confirmed that autonomic nerves preserving operation have obviously decreased the incidence of sexual as well as urinary dysfunction. (author).

  9. Provision of operational radiation protection services at nuclear power plants

    International Nuclear Information System (INIS)

    1990-01-01

    The purpose of this publication is to provide practical guidance on establishing and maintaining a radiation protection programme for a nuclear power plant that is consistent with the optimization process recommended in the Basic Safety Standards. This publication is written with a view to providing guidance to every person associated with the radiation protection programme for a nuclear power plant and develops the theme that radiation protection requires the commitment of all plant staff, including higher levels of executive management. 12 refs, 2 figs

  10. Intra-operative remifentanil might influence pain levels in the immediate postoperative period after major abdominal surgery

    DEFF Research Database (Denmark)

    Hansen, EG; Duedahl, Tina H; Rømsing, Janne

    2005-01-01

    Remifentanil, a widely used analgesic agent in anaesthesia, has a rapid onset and short duration of action. In clinical settings, this requires an appropriate pain strategy to prevent unacceptable pain in the post-operative period. The aim of this study was to investigate whether remifentanil had...... any impact on post-operative pain and opioid consumption after major abdominal surgery....

  11. Beliefs and Values about Intra-Operative Teaching and Learning: A Case Study of Surgical Teachers and Trainees

    Science.gov (United States)

    Ong, Caroline C.; Dodds, Agnes; Nestel, Debra

    2016-01-01

    Surgeons require advanced psychomotor skills, critical decision-making and teamwork skills. Much of surgical skills training involve progressive trainee participation in supervised operations where case variability, operating team interaction and environment affect learning, while surgical teachers face the key challenge of ensuring patient…

  12. Analysis of foot and ankle kinematics after operative reduction of high-grade intra-articular fractures of the calcaneus.

    Science.gov (United States)

    Hetsroni, Iftach; Nyska, Meir; Ben-Sira, David; Arnson, Yoav; Buksbaum, Chen; Aliev, Elchan; Mann, Gideon; Massarwe, Sabri; Rozenfeld, Gal; Ayalon, Moshe

    2011-05-01

    High-grade calcaneal fractures represent a complex injury, with limited data to support the advisability of open reduction. Restoration of foot and ankle kinematics during walking, which has been previously shown to be significantly limited after nonoperative treatment, has never been studied after the operation. This study was designed to address this lack of information to assess the advisability of the operation in this respect. Twenty patients with a minimum of 2 years after Open Reduction Internal Fixation (ORIF) for high-grade fractures were evaluated with a computerized gait analysis system, in addition to the radiographic assessment and functional questionnaires. Foot and ankle kinematic variables in the operated limbs were compared with contralateral limbs and with matched healthy control individuals. The kinematical gait analysis demonstrated recreation of normal ankle motions in operated patients. Subtalar motion demonstrated relative symmetry between operated and contralateral limbs, but it was still significantly limited compared with healthy controls. Bohler angle was between 15° and 35°. Functional questionnaires and rate of postoperative complications supported the generalizability of our operated group compared with previous literature assessing similar injuries. In high-grade calcaneal fractures, when recreation of gross calcaneal anatomy is obtained during the operation, walking ankle motion is recreated as well. However, subtalar motions, although recreated to a certain extent, still demonstrate limitations when compared with noninjured individuals. These results support the advisability of the operation in these complex injuries, but they demonstrate that subtalar motion is not completely normalized despite a favorable anatomic outcome.

  13. Detecting Intra-Fraction Motion in Patients Undergoing Radiation Treatment Using a Low-Cost Wireless Accelerometer

    Directory of Open Access Journals (Sweden)

    Joel J. P. C. Rodrigues

    2009-08-01

    Full Text Available The utility of a novel, high-precision, non-intrusive, wireless, accelerometerbased patient orientation monitoring system (APOMS in determining orientation change in patients undergoing radiation treatment is reported here. Using this system a small wireless accelerometer sensor is placed on a patient’s skin, broadcasting its orientation to the receiving station connected to a PC in the control area. A threshold-based algorithm is developed to identify the exact amount of the patient’s head orientation change. Through real-time measurements, an audible alarm can alert the radiation therapist if the user-defined orientation threshold is violated. Our results indicate that, in spite of its low-cost and simplicity, the APOMS is highly sensitive and offers accurate measurements. Furthermore, the APOMS is patient friendly, vendor neutral, and requires minimal user training. The versatile architecture of the APOMS makes it potentially suitable for variety of applications, including study of correlation between external and internal markers during Image-Guided Radiation Therapy (IGRT, with no major changes in hardware setup or algorithm.

  14. Limb-saving surgery by intra-operative irradiation on malignant soft tissue tumors in the foot

    International Nuclear Information System (INIS)

    Inoue, Osamu; Ibaraki, Kunio; Shimabukuro, Hiroyuki; Niigaki, Norisada; Motohana, Tetsu; Nakano, Masao

    1990-01-01

    Limb-saving surgery with combined intraoperative irradiation and intralesional resection was performed in two patients. A 10-year-old boy with recurrent desmoplastic fibroma in the right foot received intraoperative irradiation with 40 Gy. Because radiation ulcer occurred in the foot, it was covered with free flap of the musculi latissimus dorsi. In a 23-year-old man, synoviosarcoma involved in the root of the left foot was removed as soon as possible, and was exposed to electron beams of 40 Gy. Similarly, radiation ulcer was covered with free flap of the outer arm muscle. The patient remains free of local recurrence, and is able to live without any tool in the house. Care should be taken to prevent skin injury by selecting electron beams according to the depth of lesions in intraoperative irradiation of the foot. (N.K.)

  15. Limb-saving surgery by intra-operative irradiation on malignant soft tissue tumors in the foot

    Energy Technology Data Exchange (ETDEWEB)

    Inoue, Osamu; Ibaraki, Kunio; Shimabukuro, Hiroyuki; Niigaki, Norisada; Motohana, Tetsu; Nakano, Masao (University of the Rhukyus, Nishihara, Okinawa (Japan). School of Medicine)

    1990-09-01

    Limb-saving surgery with combined intraoperative irradiation and intralesional resection was performed in two patients. A 10-year-old boy with recurrent desmoplastic fibroma in the right foot received intraoperative irradiation with 40 Gy. Because radiation ulcer occurred in the foot, it was covered with free flap of the musculi latissimus dorsi. In a 23-year-old man, synoviosarcoma involved in the root of the left foot was removed as soon as possible, and was exposed to electron beams of 40 Gy. Similarly, radiation ulcer was covered with free flap of the outer arm muscle. The patient remains free of local recurrence, and is able to live without any tool in the house. Care should be taken to prevent skin injury by selecting electron beams according to the depth of lesions in intraoperative irradiation of the foot. (N.K.).

  16. Three-dimensional echocardiography: assessment of inter- and intra-operator variability and accuracy in the measurement of left ventricular cavity volume and myocardial mass

    Energy Technology Data Exchange (ETDEWEB)

    Nadkarni, S.K.; Drangova, M. [Advanced Imaging Research Laboratories, John P Robarts Research Institute, PO Box 5015, 100 Perth Drive, London, Ontario N6A 5K8 (Canada); Department of Medical Biophysics, Medical Sciences Building, University of Western Ontario, London, Ontario N6A 5C1 (Canada); Boughner, D.R. [Department of Medical Biophysics, Medical Sciences Building, University of Western Ontario, London, Ontario N6A 5C1 (Canada); London Health Sciences Centre, University Campus. London, Ontario N6A 5A5 (Canada); Fenster, A. [Advanced Imaging Research Laboratories, John P Robarts Research Institute, PO Box 5015, 100 Perth Drive, London, Ontario N6A 5K8 (Canada); Department of Medical Biophysics, Medical Sciences Building, University of Western Ontario, London, Ontario N6A 5C1 (Canada). E-mail: afenster at irus.rri.on.ca

    2000-05-01

    Accurate left ventricular (LV) volume and mass estimation is a strong predictor of cardiovascular morbidity and mortality. We propose that our technique of 3D echocardiography provides an accurate quantification of LV volume and mass by the reconstruction of 2D images into 3D volumes, thus avoiding the need for geometric assumptions. We compared the accuracy and variability in LV volume and mass measurement using 3D echocardiography with 2D echocardiography, using in vitro studies. Six operators measured the LV volume and mass of seven porcine hearts, using both 3D and 2D techniques. Regression analysis was used to test the accuracy of results and an ANOVA test was used to compute variability in measurement. LV volume measurement accuracy was 9.8% (3D) and 18.4% (2D); LV mass measurement accuracy was 5% (3D) and 9.2% (2D). Variability in LV volume quantification with 3D echocardiography was %SEM{sub inter} = 13.5%, %SEM{sub intra} = 11.4%, and for 2D echocardiography was %SEM{sub inter} = 21.5%, %SEM{sub intra} = 19.1%. We derived an equation to predict uncertainty in measurement of LV volume and mass using 3D echocardiography, the results of which agreed with our experimental results to within 13%. 3D echocardiography provided twice the accuracy for LV volume and mass measurement and half the variability for LV volume measurement as compared with 2D echocardiography. (author)

  17. Three-dimensional echocardiography: assessment of inter- and intra-operator variability and accuracy in the measurement of left ventricular cavity volume and myocardial mass

    International Nuclear Information System (INIS)

    Nadkarni, S.K.; Drangova, M.; Boughner, D.R.; Fenster, A.; Department of Medical Biophysics, Medical Sciences Building, University of Western Ontario, London, Ontario N6A 5C1

    2000-01-01

    Accurate left ventricular (LV) volume and mass estimation is a strong predictor of cardiovascular morbidity and mortality. We propose that our technique of 3D echocardiography provides an accurate quantification of LV volume and mass by the reconstruction of 2D images into 3D volumes, thus avoiding the need for geometric assumptions. We compared the accuracy and variability in LV volume and mass measurement using 3D echocardiography with 2D echocardiography, using in vitro studies. Six operators measured the LV volume and mass of seven porcine hearts, using both 3D and 2D techniques. Regression analysis was used to test the accuracy of results and an ANOVA test was used to compute variability in measurement. LV volume measurement accuracy was 9.8% (3D) and 18.4% (2D); LV mass measurement accuracy was 5% (3D) and 9.2% (2D). Variability in LV volume quantification with 3D echocardiography was %SEM inter = 13.5%, %SEM intra = 11.4%, and for 2D echocardiography was %SEM inter = 21.5%, %SEM intra = 19.1%. We derived an equation to predict uncertainty in measurement of LV volume and mass using 3D echocardiography, the results of which agreed with our experimental results to within 13%. 3D echocardiography provided twice the accuracy for LV volume and mass measurement and half the variability for LV volume measurement as compared with 2D echocardiography. (author)

  18. Assessment of the learning curves for photoselective vaporization of the prostate using GreenLight™ 180-Watt-XPS laser therapy: defining the intra-operative parameters within a prospective cohort.

    Science.gov (United States)

    Misraï, Vincent; Faron, Matthieu; Guillotreau, Julien; Bruguière, Eric; Bordier, Benoit; Shariat, Shahrokh F; Rouprêt, Morgan

    2014-04-01

    To assess the learning curves for the intra-operative parameters of the GreenLight™ 180-W XPS for photoselective vaporization of the prostate (PVP). A prospective study was conducted on 200 men who underwent PVP using the GreenLight™ 180-W XPS over 20 months. The population was divided into four consecutive equal groups. Evolution of lasing parameters was the main endpoint to reach an average energy of 5 kJ per prostate volume and to reach a lasing time/operative time (LT/OT) ratio of 66-80 %. Changes in the IPSS and prostate volume were also evaluated 12 weeks later. Total energy delivered (energy/ml of prostate) and the LT/OT ratio significantly increased over time (p learning curves within multiple intra-operative parameters. The PVP learning curves required at least 120 procedures until it met all intra-operative parameters of experts in this field.

  19. [Effects of electromagnetic radiation on health and immune function of operators].

    Science.gov (United States)

    Li, Yan-zhong; Chen, Shao-hua; Zhao, Ke-fu; Gui, Yun; Fang, Si-xin; Xu, Ying; Ma, Zi-jian

    2013-08-01

    To investigate the effects of electromagnetic radiation on the physiological indices and immune function of operators. The general conditions and electromagnetic radiation awareness rate of 205 operators under electromagnetic radiation were evaluated using a self-designed questionnaire. Physical examination, electrocardiography, and routine urine test were performed in these operators. Peripheral blood was collected from the operators under electromagnetic radiation for blood cell counting and biochemical testing, and their peripheral blood lymphocytes were cultured for determination of chromosomal aberrant frequency and micronucleus frequency. The data from these operators (exposure group) were compared with those of 95 ordinary individuals (control group). The chief complaint of giddiness, tiredness, dizziness, and amnesia showed significant differences between the exposure group and control group (P electromagnetic radiation damage was significantly higher in the exposure group than in the control group. The difference in bradycardia was significant between the two groups (P Electromagnetic radiation may lead to the changes in physiological indices, genetic effects, and immune function and affect the health and immune function in operators. The adverse effects are increased as the working years increase. So it is important to strengthen occupational protection of operators under electromagnetic radiation.

  20. SU-E-J-258: Inter- and Intra-Fraction Setup Stability and Couch Change Tolerance for Image Guided Radiation Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Teboh, Forbang R; Agee, M; Rowe, L; Creasy, T; Schultz, J; Bell, R; Wong, J; Armour, E [Johns Hopkins University, Baltimore, MD (United States)

    2014-06-01

    Purpose: Immobilization devices combine rigid patient fixation as well as comfort and play a key role providing the stability required for accurate radiation delivery. In the setup step, couch re-positioning needed to align the patient is derived via registration of acquired versus reference image. For subsequent fractions, replicating the initial setup should yield identical alignment errors when compared to the reference. This is not always the case and further couch re-positioning can be needed. An important quality assurance measure is to set couch tolerances beyond which additional investigations are needed. The purpose of this work was to study the inter-fraction couch changes needed to re-align the patient and the intra-fraction stability of the alignment as a guide to establish the couch tolerances. Methods: Data from twelve patients treated on the Accuray CyberKnife (CK) system for fractionated intracranial radiotherapy and immobilized with Aquaplast RT, U-frame, F-Head-Support (Qfix, PA, USA) was used. Each fraction involved image acquisitions and registration with the reference to re-align the patient. The absolute couch position corresponding to the approved setup alignment was recorded per fraction. Intra-fraction set-up corrections were recorded throughout the treatment. Results: The average approved setup alignment was 0.03±0.28mm, 0.15±0.22mm, 0.06±0.31mm in the L/R, A/P, S/I directions respectively and 0.00±0.35degrees, 0.03±0.32degrees, 0.08±0.45degrees for roll, pitch and yaw respectively. The inter-fraction reproducibility of the couch position was 6.65mm, 10.55mm, and 4.77mm in the L/R, A/P and S/I directions respectively and 0.82degrees, 0.71degrees for roll and pitch respectively. Intra-fraction monitoring showed small average errors of 0.21±0.21mm, 0.00±0.08mm, 0.23±0.22mm in the L/R, A/P, S/I directions respectively and 0.03±0.12degrees, 0.04±0.25degrees, and 0.13±0.15degrees in the roll, pitch and yaw respectively. Conclusion

  1. SU-E-J-258: Inter- and Intra-Fraction Setup Stability and Couch Change Tolerance for Image Guided Radiation Therapy

    International Nuclear Information System (INIS)

    Teboh, Forbang R; Agee, M; Rowe, L; Creasy, T; Schultz, J; Bell, R; Wong, J; Armour, E

    2014-01-01

    Purpose: Immobilization devices combine rigid patient fixation as well as comfort and play a key role providing the stability required for accurate radiation delivery. In the setup step, couch re-positioning needed to align the patient is derived via registration of acquired versus reference image. For subsequent fractions, replicating the initial setup should yield identical alignment errors when compared to the reference. This is not always the case and further couch re-positioning can be needed. An important quality assurance measure is to set couch tolerances beyond which additional investigations are needed. The purpose of this work was to study the inter-fraction couch changes needed to re-align the patient and the intra-fraction stability of the alignment as a guide to establish the couch tolerances. Methods: Data from twelve patients treated on the Accuray CyberKnife (CK) system for fractionated intracranial radiotherapy and immobilized with Aquaplast RT, U-frame, F-Head-Support (Qfix, PA, USA) was used. Each fraction involved image acquisitions and registration with the reference to re-align the patient. The absolute couch position corresponding to the approved setup alignment was recorded per fraction. Intra-fraction set-up corrections were recorded throughout the treatment. Results: The average approved setup alignment was 0.03±0.28mm, 0.15±0.22mm, 0.06±0.31mm in the L/R, A/P, S/I directions respectively and 0.00±0.35degrees, 0.03±0.32degrees, 0.08±0.45degrees for roll, pitch and yaw respectively. The inter-fraction reproducibility of the couch position was 6.65mm, 10.55mm, and 4.77mm in the L/R, A/P and S/I directions respectively and 0.82degrees, 0.71degrees for roll and pitch respectively. Intra-fraction monitoring showed small average errors of 0.21±0.21mm, 0.00±0.08mm, 0.23±0.22mm in the L/R, A/P, S/I directions respectively and 0.03±0.12degrees, 0.04±0.25degrees, and 0.13±0.15degrees in the roll, pitch and yaw respectively. Conclusion

  2. Construction and operation of an improved radiation calibration facility at Brookhaven National Laboratory. Environmental assessment

    International Nuclear Information System (INIS)

    1994-10-01

    Calibration of instruments used to detect and measure ionizing radiation has been conducted over the last 20 years at Brookhaven National Laboratory's (BNL) Radiation Calibration Facility, Building 348. Growth of research facilities, projects in progress, and more stringent Department of Energy (DOE) orders which involve exposure to nuclear radiation have placed substantial burdens on the existing radiation calibration facility. The facility currently does not meet the requirements of DOE Order 5480.4 or American National Standards Institute (ANSI) N323-1978, which establish calibration methods for portable radiation protection instruments used in the detection and measurement of levels of ionizing radiation fields or levels of radioactive surface contaminations. Failure to comply with this standard could mean instrumentation is not being calibrated to necessary levels of sensitivity. The Laboratory has also recently obtained a new neutron source and gamma beam irradiator which can not be made operational at existing facilities because of geometry and shielding inadequacies. These sources are needed to perform routine periodic calibrations of radiation detecting instruments used by scientific and technical personnel and to meet BNL's substantial increase in demand for radiation monitoring capabilities. To place these new sources into operation, it is proposed to construct an addition to the existing radiation calibration facility that would house all calibration sources and bring BNL calibration activities into compliance with DOE and ANSI standards. The purpose of this assessment is to identify potential significant environmental impacts associated with the construction and operation of an improved radiation calibration facility at BNL

  3. The ALICE Transition Radiation Detector: Construction, operation, and performance

    Czech Academy of Sciences Publication Activity Database

    Acharya, S.; Adamová, Dagmar; Bielčík, J.; Bielčíková, Jana; Brož, M.; Contreras, J. G.; Ferencei, Jozef; Hladký, Jan; Horák, D.; Křížek, Filip; Kučera, Vít; Kushpil, Svetlana; Lavička, R.; Mareš, Jiří A.; Petráček, V.; Šumbera, Michal; Vaňát, Tomáš; Závada, Petr

    2018-01-01

    Roč. 881, č. 2 (2018), s. 88-127 ISSN 0168-9002 R&D Projects: GA MŠk(CZ) LG15052 Institutional support: RVO:68378271 ; RVO:61389005 Keywords : fibre/foam sendwich radiator * transition radiation detector * multi-wire proportional drift chamber * Xenon-based gas micture * tracking * lonisation energy loss Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders; BF - Elementary Particles and High Energy Physics (FZU-D) OBOR OECD: Nuclear physics; Particles and field physics (FZU-D) Impact factor: 1.362, year: 2016

  4. Intra-operative Vector Flow Imaging Using Ultrasound of the Ascending Aorta among 40 Patients with Normal, Stenotic and Replaced Aortic Valves

    DEFF Research Database (Denmark)

    Hansen, Kristoffer Lindskov; Møller-Sørensen, Hasse; Kjaergaard, Jesper

    2016-01-01

    Stenosis of the aortic valve gives rise to more complex blood flows with increased velocities. The angleindependent vector flow ultrasound technique transverse oscillation was employed intra-operatively on the ascending aorta of (I) 20 patients with a healthy aortic valve and 20 patients with aor...... replacement corrects some of these changes. Transverse oscillation may be useful for assessment of aortic stenosis and optimization of valve surgery. (E-mail: lindskov@gmail.com) 2016 World Federation for Ultrasound in Medicine & Biology...... with aortic stenosis before (IIa) and after (IIb) valve replacement. The results indicate that aortic stenosis increased flow complexity (p , 0.0001), induced systolic backflow (p , 0.003) and reduced systolic jet width (p , 0.0001). After valve replacement, the systolic backflow and jet width were normalized...

  5. Intra-operative periprosthetic fractures associated with press fit stems in revision total knee arthroplasty: incidence, management, and outcomes.

    Science.gov (United States)

    Cipriano, Cara A; Brown, Nicholas M; Della Valle, Craig J; Moric, Mario; Sporer, Scott M

    2013-09-01

    The purpose of this study is to report the incidence, management, and outcomes of periprosthetic fractures associated with the insertion of press-fit stems during revision total knee arthroplasty (TKA). Immediate and six week post-operative radiographs from 634 stemmed implants (307 femoral, 327 tibial) from 420 consecutive revision TKAs were reviewed. Sixteen tibial (4.9%) and 3 femoral (1%) fractures (combined incidence 3.0%) were identified. All healed uneventfully without operative intervention, with no evidence of implant loosening at a mean of 23 months (range 12 to 47 months). The technique of tightly press fitting stems into the diaphysis is associated with a small rate (3%) of periprosthetic fractures; most were non or minimally displaced, all healed uneventfully with non-operative management and were not associated with implant loosening. Copyright © 2013 Elsevier Inc. All rights reserved.

  6. 76 FR 28850 - Northern Plains Railroad, Inc.-Intra-Corporate Family Operation Exemption-Mohall Central Railroad...

    Science.gov (United States)

    2011-05-18

    ... Railroad, Inc. (NPR), a Class III rail common carrier, has filed a verified notice of exemption under 49... to operate the rail line of Mohall Central Railroad, Inc. (MHC), also a Class III rail carrier.\\1...\\ however, since MHC became a Class III rail carrier, it has abandoned 2 segments of its rail line.\\3\\ This...

  7. The detection of intra-operative myocardial ischaemia. Preliminary experience with the right-sided precordial lead

    NARCIS (Netherlands)

    de Hert, S. G.; de Jongh, R. F.; van den Bossche, A. O.; de Maere, P. L.; Adriaensen, H. F.

    1989-01-01

    The value of monitoring the right precordial lead, V4R, to detect peri-operative ischaemic events during coronary artery surgery was studied in 60 patients. Thirty-four patients had only left-sided coronary disease (Group 1). The other 26 patients had both left-sided occlusive coronary artery

  8. Spindle cell oncocytoma of the adenohypophysis: 2 case reports of unusual radiological and intra-operative findings

    Directory of Open Access Journals (Sweden)

    Nasir M. Rafiq

    2017-12-01

    Conclusion: SCO is a rare entity, difficult to identify on clinical basis alone, but with different radiological and surgical operative features compared to typical pituitary adenomas. This tumour should be suspected preoperatively if an isointense and well delineated pituitary mass is identified, or unusually during resection when a hard consistency is noted.

  9. Intra-Abdominal Hydatid Cyst: Sociodemographics, Clinical Profiles, and Outcomes of Patients Operated on at a Tertiary Hospital in Addis Ababa, Ethiopia

    Directory of Open Access Journals (Sweden)

    Engida Abebe

    2017-01-01

    Full Text Available Background. Hydatid cyst is caused by the tapeworm Echinococcus granulosus. The abdomen, specifically the liver, is the most common site affected. Objective. Determine the presentation patterns, types of surgical management, and outcomes of patients operated for intra-abdominal hydatid cyst (IAHC. Methodology. A retrospective descriptive study of patients admitted and operated for IAHC from September 1, 2011, to August 31, 2015. Results. Forty-two patients whose age ranged from 10 to 65 (mean of 37 years were operated on. Females comprised 27 (64.3% of the patients. The commonest presenting complaint was abdominal pain (41, 97.6%. Abdominal mass was documented in 23 (54.7% cases. Abdominal ultrasound (AUS and CT were the main imaging studies done on 38 (90.5% and 24 (57.1% patients, respectively. Cysts measuring more than 10 cm in diameter were the most common finding in both studies. Liver was the primary site involved, 30 (71.4% cases, the right lobe being the main side, 73%. Thirty-eight (90.5% patients underwent deroofing, evacuation, marsupialization, and omentoplasty (DEMO. There was no perioperative death, but 4 (9.5% of the patients had post-op complications. Conclusion. Abdominal pain was the most common presenting complaint. AUS and CT remain the preferred imaging. DEMO was the most common surgery.

  10. The radiation dose dilemma in the hybrid operating room

    NARCIS (Netherlands)

    de Ruiter, QMB

    2016-01-01

    The of the hybrid Operation room (an operation room combined with advanced radiological X-ray equipment) is gaining popularity, as it is now the preferred room to perform (complex) endovascular aortic procedures. The fixed C-arms equipped in these rooms make it possible to gain very high image

  11. High intensity radiated field external environments for civil aircraft operating in the United States of America

    Science.gov (United States)

    1998-12-01

    NAWCAD Patuxent River, Maryland, was tasked by the FAA to determine the High Intensity Radiated Field (HIRF) levels for civil aircraft operating in the U.S. The electromagnetic field survey will apply to civil aircraft seeking FAA certification under...

  12. Survey on radiation safety management (RSM) among Korean radiation workers who operate radiation generators or handle radioactive isotopes.

    Science.gov (United States)

    Ryu, Young-Hwan; Cho, Jae-Hwan; Dong, Kyung-Rae; Chung, Woon-Kwan; Lee, Jong-Woong; Choi, Eun-Jin

    2014-01-01

    This study examined the knowledge, attitudes, and behaviors of radiation workers to radiation safety management (RSM) using survey questionnaires. Radiation workers are those who handle radiation generators, radioactive isotopes, and other radioactive materials for industrial uses. The survey was distributed to 861 radiation workers between 1 August to 5 September 2011. A knowledge of, awareness of, attitude toward, and behaviors related to RSM were analyzed by comparing the means and standard deviations. Both the knowledge and awareness of RSM among radiation workers were high. Although all questions about the awareness of RSM were answered correctly, there were also many negative responses. All questions regarding the attitude of radiation workers toward RSM were answered correctly, and their attitude toward and awareness of RSM were high. Overall, the results demonstrated that safety management is not taken seriously in many cases, highlighting the need for proper education in the future to raise awareness among radiation workers. Furthermore, it is important to establish a foundation for the efficient use of radiation based on the continuous management of radiation workers.

  13. Radiation dose reduction for CT assessment of urolithiasis using iterative reconstruction. A prospective intra-individual study

    Energy Technology Data Exchange (ETDEWEB)

    Harder, Annemarie M. den; Willemink, Martin J.; Wessels, Frank J.; Schilham, Arnold M.R.; Leiner, Tim; Jong, Pim A. de [Utrecht University Medical Center, Department of Radiology, Utrecht (Netherlands); Doormaal, Pieter J. van; Budde, Ricardo P.J. [Erasmus Medical Center, Department of Radiology, Rotterdam (Netherlands); Lock, M.T.W.T. [University Medical Center, Department of Urology, Utrecht (Netherlands)

    2018-01-15

    To assess the performance of hybrid (HIR) and model-based iterative reconstruction (MIR) in patients with urolithiasis at reduced-dose computed tomography (CT). Twenty patients scheduled for unenhanced abdominal CT for follow-up of urolithiasis were prospectively included. Routine dose acquisition was followed by three low-dose acquisitions at 40%, 60% and 80% reduced doses. All images were reconstructed with filtered back projection (FBP), HIR and MIR. Urolithiasis detection rates, gall bladder, appendix and rectosigmoid evaluation and overall subjective image quality were evaluated by two observers. 74 stones were present in 17 patients. Half the stones were not detected on FBP at the lowest dose level, but this improved with MIR to a sensitivity of 100%. HIR resulted in a slight decrease in sensitivity at the lowest dose to 72%, but outperformed FBP. Evaluation of other structures with HIR at 40% and with MIR at 60% dose reductions was comparable to FBP at routine dose, but 80% dose reduction resulted in non-evaluable images. CT radiation dose for urolithiasis detection can be safely reduced by 40 (HIR)-60 (MIR) % without affecting assessment of urolithiasis, possible extra-urinary tract pathology or overall image quality. (orig.)

  14. Superselective intra-arterial infusion of high-dose cisplatin combined with radiation therapy for head and neck carcinoma. Experience of Yamagata University Hospital

    Energy Technology Data Exchange (ETDEWEB)

    Hamamoto, Yasushi; Niino, Keiji; Ishiyama, Hiromichi; Koike, Shuji; Hosoya, Takaaki; Aoyagi, Masaru [Yamagata Univ. (Japan). School of Medicine

    2003-03-01

    Local effectiveness and complication of superselective intra-arterial infusion of high-dose cisdiamminedichloroplatinum (CDDP) (SIC) combined with radiation therapy (RT) were investigated. Between 1998 and 2000, 18 head and neck carcinomas including 10 maxillary carcinomas (T3; 1, T4; 9), 3 oral cavity carcinomas (T2; 1, T4; 2), and 5 oropharyngeal carcinomas (T2; 2, T4; 3) were treated with SIC and RT with or without surgery. CDDP of 100-150 mg/body was administered weekly in principle for 2-9 weeks (mean: 4.9) with the simultaneous administration of sodium thiosulfate. Radiation doses ranged from 40 Gy to 70 Gy (mean: 56.8 Gy). Complete response was obtained in 7 of 10 maxillary carcinomas, 2 of 3 oral-cavity carcinomas, and 2 of 5 oropharyngeal carcinomas, respectively. When surgical intervention was performed if necessary, 2-year local control rates for maxillary carcinoma, and other carcinoma including oral-cavity carcinoma and oropharyngeal carcinoma were 80% and 63% respectively. Two-year local control rates for T4 maxillary carcinoma, and other T4 carcinoma including oral-cavity carcinoma and oropharyngeal carcinoma were 78% and 40% respectively. Two-year overall survival rates for all cases, maxillary carcinoma, and oral-cavity/oropharyngeal carcinoma were 88%, 90% and 86% respectively. All local recurrences occurred within 6 months from the initiation of treatment. The systemic toxicity of weekly SIC was comparatively mild; however, a total CDDP dose of 1,000 mg or more and/or RT of 70 Gy induced complications of local soft tissue such as mucosal ulcer and fistula. SIC combined with RT is useful to improve the local control/survival rates and to avoid the aggressive surgery for locally advanced head and neck carcinoma. A high total dose of CDDP and/or RT of a comparatively high dose may be risk factors for local soft tissue complications. (author)

  15. Unexpected refractory intra-operative hypotension during non-cardiac surgery: Diagnosis and management guided by trans-oesophageal echocardiography

    Directory of Open Access Journals (Sweden)

    Sundara Reddy

    2014-01-01

    Full Text Available We present a case of severe refractory hypotension in a patient undergoing de-bulking liver resection for massive polycystic liver disease. Emergent trans-oesophageal echocardiography (TOE revealed dynamic left ventricular outflow tract (LVOT obstruction with systolic anterior motion (SAM of the anterior mitral leaflet (AML. Notably, he had a structurally normal heart on pre-operative trans-thoracic echocardiography (TTE. Diagnosis of SAM by TOE, possible mechanisms and specific management of refractory hypotension in this context are discussed.

  16. A comparative study to validate the use of ultrasonography and computed tomography in patients with post-operative intra-abdominal sepsis

    International Nuclear Information System (INIS)

    Go, H.L.S.; Baarslag, H.J.; Vermeulen, H.; Lameris, J.S.; Legemate, D.A.

    2005-01-01

    Purpose: To validate abdominal ultrasonography and helical computed tomography in detecting causes for sepsis in patients after abdominal surgery and to determine improved criteria for its use. Materials and methods: Eighty-five consecutive surgical patients primarily operated for non-infectious disease were included in this prospective study. Forty-one patients were admitted to the intensive care unit. All patients were suspected of an intra-abdominal sepsis after abdominal surgery. Both ultrasonography (US) and helical abdominal computed tomography (CT) were performed to investigate the origin of an intra-abdominal sepsis. The images of both US and CT were interpreted on a four-point scale by different radiologists or residents in radiology, the investigators were blinded of each other's test. Interpretations of US and CT were compared with a reference standard which was defined by the result of diagnostic aspiration of suspected fluid collections (re)laparotomy, clinical course or the opinion of an independent panel. Likelihood ratios and post-test probabilities were calculated and interobserver agreement was determined using κ statistics. Results: The overall prevalence of an abdominal infection was 0.49. The likelihood ratio (LR) of a positive test-result for US was 1.33 (95% CI: 0.8-2.5) and for CT scan 2.53 (95% CI: 1.4-5.0); corresponding post-test probabilities for US 0.57 (95% CI: 0.42-0.70) and for CT 0.71 (95% CI: 0.57-0.83). The LR of a negative test-result was, respectively, 0.60 (95% CI: 0.3-1.3) and 0.18 (95% CI: 0.06-0.5); corresponding post-test probabilities for US 0.37 (95% CI: 0.20-0.57) and for CT 0.15 (95% CI: 0.06-0.32) were calculated. Conclusion: Computed tomography can be used as the imaging modality of choice in patients suspected of intra-abdominal sepsis after abdominal surgery. Because of the low discriminatory power ultrasonography should not be performed as initial diagnostic test

  17. A comparative study to validate the use of ultrasonography and computed tomography in patients with post-operative intra-abdominal sepsis

    Energy Technology Data Exchange (ETDEWEB)

    Go, H.L.S. [Department of Radiology, Academic Medical Center, University of Amsterdam, C-1, P.O. Box 22660, 1100 DD Amsterdam (Netherlands); Department of Surgery, Academic Medical Center, University of Amsterdam, Room G4-111, P.O. Box 22700, 1100 DE Amsterdam (Netherlands); Baarslag, H.J. [Department of Radiology, Academic Medical Center, University of Amsterdam, C-1, P.O. Box 22660, 1100 DD Amsterdam (Netherlands); Vermeulen, H. [Department of Surgery, Academic Medical Center, University of Amsterdam, Room G4-111, P.O. Box 22700, 1100 DE Amsterdam (Netherlands); Lameris, J.S. [Department of Radiology, Academic Medical Center, University of Amsterdam, C-1, P.O. Box 22660, 1100 DD Amsterdam (Netherlands); Legemate, D.A. [Department of Surgery, Academic Medical Center, University of Amsterdam, Room G4-111, P.O. Box 22700, 1100 DE Amsterdam (Netherlands)]. E-mail: d.a.legemate@amc.uva.nl

    2005-06-01

    Purpose: To validate abdominal ultrasonography and helical computed tomography in detecting causes for sepsis in patients after abdominal surgery and to determine improved criteria for its use. Materials and methods: Eighty-five consecutive surgical patients primarily operated for non-infectious disease were included in this prospective study. Forty-one patients were admitted to the intensive care unit. All patients were suspected of an intra-abdominal sepsis after abdominal surgery. Both ultrasonography (US) and helical abdominal computed tomography (CT) were performed to investigate the origin of an intra-abdominal sepsis. The images of both US and CT were interpreted on a four-point scale by different radiologists or residents in radiology, the investigators were blinded of each other's test. Interpretations of US and CT were compared with a reference standard which was defined by the result of diagnostic aspiration of suspected fluid collections (re)laparotomy, clinical course or the opinion of an independent panel. Likelihood ratios and post-test probabilities were calculated and interobserver agreement was determined using {kappa} statistics. Results: The overall prevalence of an abdominal infection was 0.49. The likelihood ratio (LR) of a positive test-result for US was 1.33 (95% CI: 0.8-2.5) and for CT scan 2.53 (95% CI: 1.4-5.0); corresponding post-test probabilities for US 0.57 (95% CI: 0.42-0.70) and for CT 0.71 (95% CI: 0.57-0.83). The LR of a negative test-result was, respectively, 0.60 (95% CI: 0.3-1.3) and 0.18 (95% CI: 0.06-0.5); corresponding post-test probabilities for US 0.37 (95% CI: 0.20-0.57) and for CT 0.15 (95% CI: 0.06-0.32) were calculated. Conclusion: Computed tomography can be used as the imaging modality of choice in patients suspected of intra-abdominal sepsis after abdominal surgery. Because of the low discriminatory power ultrasonography should not be performed as initial diagnostic test.

  18. Space Electronics Operating at High Temperatures and Radiation Levels Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposal represents a radical revolution in Power Management & Distribution (PMAD) that addresses many of the challenges for NASA missions that will operate...

  19. Systematic Review and Meta-Analysis of Randomized Controlled Trials Evaluating Prophylactic Intra-Operative Wound Irrigation for the Prevention of Surgical Site Infections.

    Science.gov (United States)

    de Jonge, Stijn W; Boldingh, Quirine J J; Solomkin, Joseph S; Allegranzi, Benedetta; Egger, Matthias; Dellinger, E Patchen; Boermeester, Marja A

    Surgical site infections (SSIs) are one of the most common hospital-acquired infections. To reduce SSIs, prophylactic intra-operative wound irrigation (pIOWI) has been advocated, although the results to date are equivocal. To develop recommendations for the new World Health Organization (WHO) SSI prevention guidelines, a systematic literature review and a meta-analysis were conducted on the effectiveness of pIOWI using different agents as a means of reducing SSI. The PUBMED, Embase, CENTRAL, CINAHL, and WHO databases were searched. Randomized controlled trials (RCTs) comparing either pIOWI with no pIOWI or with pIOWI using different solutions and techniques were retrieved with SSI as the primary outcome. Meta-analyses were performed, and odds ratios (OR) and the mean difference with 95% confidence intervals (CI) were extracted and pooled with a random effects model. Twenty-one studies were suitable for analysis, and a distinction was made between intra-peritoneal, mediastinal, and incisional wound irrigation. A low quality of evidence demonstrated a statistically significant benefit for incisional wound irrigation with an aqueous povidone-iodine (PVP-I) solution in clean and clean contaminated wounds (OR 0.31; 95% CI 0.13-0.73; p = 0.007); 50 fewer SSIs per 1,000 procedures (from 19 fewer to 64 fewer)). Antibiotic irrigation had no significant effect in reducing SSIs (OR 1.16; 95% CI 0.64-2.12; p = 0.63). Low-quality evidence suggests considering the use of prophylactic incisional wound irrigation to prevent SSI with an aqueous povidone-iodine solution. Antibiotic irrigation does not show a benefit and therefore is discouraged.

  20. Sexual Functioning Among Endometrial Cancer Patients Treated With Adjuvant High-Dose-Rate Intra-Vaginal Radiation Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Damast, Shari, E-mail: shari.damast@yale.edu [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Alektiar, Kaled M. [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Goldfarb, Shari [Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Eaton, Anne; Patil, Sujata [Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Mosenkis, Jeffrey [Department of Comparative Human Development, University of Chicago, Chicago, Illinois (United States); Bennett, Antonia [Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Atkinson, Thomas [Department of Psychiatry, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Jewell, Elizabeth; Leitao, Mario; Barakat, Richard; Carter, Jeanne [Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Basch, Ethan [Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York (United States)

    2012-10-01

    Purpose: We used the Female Sexual Function Index (FSFI) to investigate the prevalence of sexual dysfunction (SD) and factors associated with diminished sexual functioning in early stage endometrial cancer (EC) patients treated with simple hysterectomy and adjuvant brachytherapy. Methods and Materials: A cohort of 104 patients followed in a radiation oncology clinic completed questionnaires to quantify current levels of sexual functioning. The time interval between hysterectomy and questionnaire completion ranged from <6 months to >5 years. Multivariate regression was performed using the FSFI as a continuous variable (score range, 1.2-35.4). SD was defined as an FSFI score of <26, based on the published validation study. Results: SD was reported by 81% of respondents. The mean ({+-} standard deviation) domain scores in order of highest-to-lowest functioning were: satisfaction, 2.9 ({+-}2.0); orgasm, 2.5 ({+-}2.4); desire, 2.4 ({+-}1.3); arousal, 2.2 ({+-}2.0); dryness, 2.1 ({+-}2.1); and pain, 1.9 ({+-}2.3). Compared to the index population in which the FSFI cut-score was validated (healthy women ages 18-74), all scores were low. Compared to published scores of a postmenopausal population, scores were not statistically different. Multivariate analysis isolated factors associated with lower FSFI scores, including having laparotomy as opposed to minimally invasive surgery (effect size, -7.1 points; 95% CI, -11.2 to -3.1; P<.001), lack of vaginal lubricant use (effect size, -4.4 points; 95% CI, -8.7 to -0.2, P=.040), and short time interval (<6 months) from hysterectomy to questionnaire completion (effect size, -4.6 points; 95% CI, -9.3-0.2; P=.059). Conclusions: The rate of SD, as defined by an FSFI score <26, was prevalent. The postmenopausal status of EC patients alone is a known risk factor for SD. Additional factors associated with poor sexual functioning following treatment for EC included receipt of laparotomy and lack of vaginal lubricant use.

  1. Sexual Functioning Among Endometrial Cancer Patients Treated With Adjuvant High-Dose-Rate Intra-Vaginal Radiation Therapy

    International Nuclear Information System (INIS)

    Damast, Shari; Alektiar, Kaled M.; Goldfarb, Shari; Eaton, Anne; Patil, Sujata; Mosenkis, Jeffrey; Bennett, Antonia; Atkinson, Thomas; Jewell, Elizabeth; Leitao, Mario; Barakat, Richard; Carter, Jeanne; Basch, Ethan

    2012-01-01

    Purpose: We used the Female Sexual Function Index (FSFI) to investigate the prevalence of sexual dysfunction (SD) and factors associated with diminished sexual functioning in early stage endometrial cancer (EC) patients treated with simple hysterectomy and adjuvant brachytherapy. Methods and Materials: A cohort of 104 patients followed in a radiation oncology clinic completed questionnaires to quantify current levels of sexual functioning. The time interval between hysterectomy and questionnaire completion ranged from 5 years. Multivariate regression was performed using the FSFI as a continuous variable (score range, 1.2-35.4). SD was defined as an FSFI score of <26, based on the published validation study. Results: SD was reported by 81% of respondents. The mean (± standard deviation) domain scores in order of highest-to-lowest functioning were: satisfaction, 2.9 (±2.0); orgasm, 2.5 (±2.4); desire, 2.4 (±1.3); arousal, 2.2 (±2.0); dryness, 2.1 (±2.1); and pain, 1.9 (±2.3). Compared to the index population in which the FSFI cut-score was validated (healthy women ages 18-74), all scores were low. Compared to published scores of a postmenopausal population, scores were not statistically different. Multivariate analysis isolated factors associated with lower FSFI scores, including having laparotomy as opposed to minimally invasive surgery (effect size, −7.1 points; 95% CI, −11.2 to −3.1; P<.001), lack of vaginal lubricant use (effect size, −4.4 points; 95% CI, −8.7 to −0.2, P=.040), and short time interval (<6 months) from hysterectomy to questionnaire completion (effect size, −4.6 points; 95% CI, −9.3-0.2; P=.059). Conclusions: The rate of SD, as defined by an FSFI score <26, was prevalent. The postmenopausal status of EC patients alone is a known risk factor for SD. Additional factors associated with poor sexual functioning following treatment for EC included receipt of laparotomy and lack of vaginal lubricant use.

  2. Intra-Operative Airway Management in Patients with Maxillofacial Trauma having Reduction and Immobilization of Facial Fractures.

    Science.gov (United States)

    Osinaike, Babatunde Babasola; Gbolahan, Olalere O; Olusanya, Adeola A

    2015-01-01

    Despite advancements in airway management, treatment of fractures in the maxillofacial region under general anesthesia remains a unique anesthetic challenge. We reviewed the pattern of airway management in patients with maxillofacial fractures and assessed those challenges associated with the different airway management techniques employed. The anesthetic chart, theatre and maxillofacial operations records of patients who had reduction and immobilization of various maxillofacial fractures over a 2-year period were reviewed. Information obtained included the patient demographics, mechanisms of injury, types of fractures and details about airway management. Statistical Package for Social Sciences, SPSS version 17.0 was utilized for all data analysis. Fifty-one patients were recruited during the 2-year study period. Mask ventilation was easy in 80-90% of the patients, 80% had Mallampati three or four, while 4 (7.8%) had laryngoscopy grading of 4. There was no statistically significant difference between the fracture groups in terms of the laryngoscopy grading (P = 0.153) but there was statistical significant difference in the technique of airway management (P = 0.0001). Nasal intubation following direct laryngoscopy was employed in 64.7% of the patients, fiber-optic guided nasal intubation was utilized in only 7.8%. None of the patients had tracheostomy either before or during operative management. Laryngoscopic grading and not adequacy of mouth opening predicted difficult intubation in this group of patients in the immediate preoperative period. Despite the distortions in the anatomy of the upper airway that may result from maxillofacial fractures, nasal intubation following direct laryngoscopy may be possible in many patients with maxillofacial fractures.

  3. Intra-arterial administration of carboplatin plus lower dosage radiation of {sup 60}CO as induction treatment in advanced oral cancer

    Energy Technology Data Exchange (ETDEWEB)

    Okutomi, Tadashi; Kato, Yukihiro; Ichihara, Hideki; Kusunoki, Yukihiro; Hatakeyama, Daijiro; Yokoyama, Kyoko; Tatematsu, Norichika [Gifu Univ. (Japan). School of Medicine; Liu, Jianhua

    2000-11-01

    Conventional pre-operative chemoradiotherapy often causes severe side effects, which may result in interruption of the treatment and delay of decided operation. Carboplatin (CBDCA) is one of the effective chemotherapeutants for head and neck cancer. We treated 23 patients with advanced oral cancers by a combination of intra-arterial administration of Carboplatin and {sup 60}CO radiotherapy. The dosage of Carboplatin was between 20 mg and 35 mg per square meter of body surface. The dosage of external {sup 60}CO irradiation was 2 Gy per day and 30 to 60 Gy in total. We evaluated clinical response, toxicity and survival of this therapy of all the patients. Histologic response was also evaluated in some of them. All cancers responded to the regional chemoradiotherapy and demonstrated remission. Two (8%) completed response rate (CR) and 16 (69%) partial response rate (PR) were achieved. The accumulated five-year overall survival rate by Kaplan-Meier method was 73.9%. Fourteen patients (60.8%) showed no evidence of disease (NED) within five years after the therapy. All patients had stomatitis, but most of them were not so severe. The major hematological toxicity was leukopenia, but it was from mild to moderate and reversible. Our study showed that this therapy provided low toxicity, high clinical and histological response rate. (author)

  4. Patient-specific instrumentation for total knee arthroplasty does not match the pre-operative plan as assessed by intra-operative computer-assisted navigation.

    Science.gov (United States)

    Scholes, Corey; Sahni, Varun; Lustig, Sebastien; Parker, David A; Coolican, Myles R J

    2014-03-01

    The introduction of patient-specific instruments (PSI) for guiding bone cuts could increase the incidence of malalignment in primary total knee arthroplasty. The purpose of this study was to assess the agreement between one type of patient-specific instrumentation (Zimmer PSI) and the pre-operative plan with respect to bone cuts and component alignment during TKR using imageless computer navigation. A consecutive series of 30 femoral and tibial guides were assessed in-theatre by the same surgeon using computer navigation. Following surgical exposure, the PSI cutting guides were placed on the joint surface and alignment assessed using the navigation tracker. The difference between in-theatre data and the pre-operative plan was recorded and analysed. The error between in-theatre measurements and pre-operative plan for the femoral and tibial components exceeded 3° for 3 and 17% of the sample, respectively, while the error for total coronal alignment exceeded 3° for 27% of the sample. The present results indicate that alignment with Zimmer PSI cutting blocks, assessed by imageless navigation, does not match the pre-operative plan in a proportion of cases. To prevent unnecessary increases in the incidence of malalignment in primary TKR, it is recommended that these devices should not be used without objective verification of alignment, either in real-time or with post-operative imaging. Further work is required to identify the source of discrepancies and validate these devices prior to routine use. II.

  5. Focused parathyroidectomy without intra-operative parathormone monitoring: The value of PTH assay in preoperative ultrasound guided fine needle aspiration washout.

    Science.gov (United States)

    Kuzu, Fatih; Arpaci, Dilek; Cakmak, Guldeniz Karadeniz; Emre, Ali Ugur; Elri, Tarik; Ilikhan, Sevil Uygun; Bahadir, Burak; Bayraktaoglu, Taner

    2016-03-01

    The accurate identification of hyperfunctioning parathyroid (HP) gland is the only issue for definitive surgical treatment in primary hyperparathyroidism (pHPT). Various imaging and operative techniques have been proposed to confirm the localization of the diseased gland. Nevertheless, none of these methods proved to be the gold standard. The presented study aimed to assess the value of parathyroid hormone assay in preoperative ultrasound guided fine needle aspiration (FNA)-PTH washout fluid to verify the correct localisation for focused parathyroidectomy without intra-operative PTH monitoring. The retrospective analysis of 57 patients with pHPT who underwent FNA-PTH was conducted from a prospective database. Biochemical assessment together with radiological (ultrasonography) and nuclear (MIBI scan) imaging was reviewed. Associations between FNA-PTH washout values and localization technics were evaluated and compared in terms of operative findings. Focused parathyroidectomy without intraoperative PTH monitoring was performed to 45 patients with high FNA-PTH values. The median largest diameter of the target parathyroid lesion identified by ultrasonography was 13 mm (range, 6 to 36). The median serum PTH level was 190 pg/mL (range, 78 to 1709; reference range, 15 to 65) whereas the median washout PTH was 2500 pg/mL (range, 480 to 3389). According to operative findings high FNA-PTH levels correctly identified parathyroid adenoma in 40 cases (89% of sensitivity and 100% of specificity and positive predictive value) whereas MIBI scan localized the lesion in 36 of these cases (80% of sensitivity). The higher level of PTH in preoperative ultrasound guided FNA washout is a considerable data to predict the correct localization of HP, particularly in circumstances of greater values than the serum PTH level. However, although its specificity is high, in cases of coexisting nodular thyroid disease, associated additional HP might be missed at focused parathyroidectomy

  6. Examples of radiation protection optimization in design and operation

    International Nuclear Information System (INIS)

    Gonzalez, A.J.; Palacios, E.; Curti, A.; Agatiello, O.; Majchrzak, J.

    1982-01-01

    The practical use of the requirement of optimization of radiological protection is presented. Application examples for designing ventilation systems and for maintenance operations of nuclear plants are given. A method is developed for the application of the optimization requirement to the design of ventilation systems in contaminated environments. Representative values of the main parameters are presented and their relevant features are discussed. A practical example shows actual results for a radioisotope production plant. Causes influencing collective doses incurred by the workers during maintenance operations are analyzed. A method is presented for the optimization of both the level of training of personnel and the apportionment of individual doses. As an example, this methodology is applied to the maintenance operations in a nuclear power plant. (author)

  7. The efficacy, safety and cost-effectiveness of intra-operative cell salvage in high-bleeding-risk cardiac surgery with cardiopulmonary bypass: a prospective randomized and controlled trial.

    Science.gov (United States)

    Xie, Yihong; Shen, Sheliang; Zhang, Jun; Wang, Wenyuan; Zheng, Jiayin

    2015-01-01

    Intra-operative cell salvage (CS) was reported to be ineffective, safe and not cost-effective in low-bleeding-risk cardiac surgery with cardiopulmonary bypass (CPB), but studies in high-bleeding-risk cardiac surgery are limited. The objective of this study is to evaluate the efficacy, safety and cost-effectiveness of intra-operative CS in high-bleeding-risk cardiac surgery with CPB. One hundred and fifty patients were randomly assigned to either with intra-operative CS group (Group CS) or without intra-operative CS group (Group C). Study endpoints were defined as perioperative allogeneic red blood cell (RBC) transfusion, perioperative impairment of blood coagulative function, postoperative adverse events and costs of transfusion-related. Both the proportion and quantity of perioperative allogeneic RBC transfusion were significantly lower in Group CS than that in Group C (p=0.0002, operative CS in high-bleeding-risk cardiac surgery with CPB is effective, generally safe, and cost-effective in developed countries but not in China.

  8. Randomised study on single stage laparo-endoscopic rendezvous (intra-operative ERCP procedure versus two stage approach (Pre-operative ERCP followed by laparoscopic cholecystectomy for the management of cholelithiasis with choledocholithiasis

    Directory of Open Access Journals (Sweden)

    Manash Ranjan Sahoo

    2014-01-01

    Full Text Available Introduction : The ′Rendezvous′ technique consists of laparoscopic cholecystectomy (LC standards with intra-operative cholangiography followed by endoscopic sphincterotomy. The sphincterotome is driven across the papilla through a guidewire inserted by the transcystic route. In this study, we intended to compare the two methods in a prospective randomised trial. Materials And Methods: From 2005 to 2012, we enrolled 83 patients with a diagnosis of cholecysto-choledocolithiasis. They were randomised into two groups. In ′group-A′,41 patients were treated with two stages management, first by pre-operative endoscopic retrograde cholangiopancreatography (ERCP and common bile duct (CBD clearance and second by LC. In ′group-B′, 42 patients were treated with LC and intra-operative cholangiography; and when diagnosis of choledocholithiasis was confirmed, patients had undergone one stage management of by Laparo-endoscopic Rendezvous technique. Results: In arm-A and arm-B groups, complete CBD clearance was achieved in 29 and 38 patients, respectively. Failure of the treatment in arm-A was 29% and in arm-B was 9.5%. In arm-A, selective CBD cannulation was achieved in 33 cases (80.5% and in arm-B in 39 cases (93%. In arm-Agroup, post-ERCP hyperamylasia was presented in nine patients (22% and severe pancreatitis in five patients (12% versus none of the patients (0% in arm-B group, respectively. Mean post-operative hospital stay in arm-A and arm-B groups are 10.9 and 6.8 days, respectively. Conclusion: One stage laparo-endoscopic rendezvous approach increases selective cannulation of CBD, reduces post-ERCP pancreatitis, reduces days of hospital stay, increases patient′s compliance and prevents unnecessary intervention to CBD.

  9. McConnell's sign in intra-operative acute right ventricle ischaemia: An under-recognized aetiology.

    Science.gov (United States)

    Longo, S A; Echegaray, A; Acosta, C M; Rinaldi, L I; Cabrera Schulmeyer, M C; Olavide Goya, I

    2016-11-01

    Transoesophageal echocardiography (TEE) has become a fundamental tool in modern cardiothoracic anaesthesia. It has an indisputable role in coronary valve surgery and revascularisations with severe impairment of ventricle function. It helps in making diagnoses that can optimise the surgical strategy and to minimal invasively dynamically monitor volaemia and cardiac function during the post-operative period, detecting complications unobservable by other methods. The McConnell sign, visualised using TEE as an akinesis of the right ventricular free wall, with a normal apex motility and enlargement of the right cavities, is characteristic of right ventricular (RV) dysfunction. This sign has a 77% sensitivity and 94% specificity for the diagnosis of acute pulmonary embolism (APE). The case is presented of a 53-year-old man scheduled for aortic valve and ascending aorta replacement surgery, with a history of severe valve aortic stenosis, aortic root and arch aneurysm, and with normal coronary arteries. Post-cardiopulmonary bypass (CBP), the patient presented with haemodynamic instability, with the TEE showing a typical image of the McConnell sign, with no pulmonary hypertension. This enabled making an early diagnosis of acute RV ischaemia, that led to a change in the surgical plan, the performing of coronary revascularisation surgery. As a result, the McConnell sign, which describes the characteristics of RV dysfunction, led to making a differential diagnosis between APE, RV infarction and acute myocardial ischaemia. Copyright © 2016 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

  10. Primer on theory and operation of linear accelerators in radiation therapy

    International Nuclear Information System (INIS)

    Karzmark, C.J.; Morton, R.J.

    1981-12-01

    This primer is part of an educational package that also includes a series of 3 videotapes entitled Theory and Operation of Linear Accelerators in Radiation Therapy, Parts I, II, and III. This publication provides an overview of the components of the linear accelerator and how they function and interrelate. The auxiliary systems necessary to maintain the operation of the linear accelerator are also described

  11. Technology development for evaluation of operational quantities in radiation protection

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jang Lyul; Chang, S. Y.; Lee, L. T.; Kim, B. H.; Chung, K. K.; Lee, J. I.; Lim, G. S.; Kim, J. S.; Nam, Y. M.; Chang, J. K.; Kim, D. Y.; Yang, J. S

    2000-03-01

    A study on the fabrication of a new personal thermo-luminescence dosimeter, which can evaluate the personal dose equivalent H{sub p}(d), has been performed. Optimum conditions for fabrication of a LiF:Mg,Cu,Na,Si TL phosphor powder has been determined and a disc type TL pellet has been fabricated from this TL powder. Another type of CaSO{sub 4}:Dy,Mo TL material has been also fabricated. These two TL materials have shown greater TL sensitivity than the foreign-made commercial TL materials. Mono-energetic fluorescence X-ray from 8.6 keV to 75 keV for use in performance testing of the developed TLDs energy response have been constructed and evaluated for the performance of the purity, air kerma, beam uniformity and distribution, and scattered fraction of X-rays. Reference neutron field of a D{sub 2}O moderated {sup 252}Cf source was characterized and the irradiation system using {sup 226}Ra and {sup 137}Cs sources was installed to construct the environmental gamma reference radiation and the low-level gamma radiation. A capability of calibration and measurement of KAERI In Vivo counting system for transuranic elements in the lung has been evaluated through the participation in the overseas intercomparison study on the In Vivo radioactivity measurement. An improvement and advancement of KAERI lung counting technology have been made by the analysis off uncertainties from the assumption of uniform radioactivity distribution in the lung, experimental determination and comparing of detection efficiency with different lung sets, and mathematical efficiency calibration of In Vivo counting system. (author)

  12. Efficacy and safety evaluation of intra-articular injection of tranexamic acid in total knee arthroplasty operation with temporarily drainage close

    Science.gov (United States)

    Wang, Guowei; Wang, Dong; Wang, Bingchen; Lin, Yongjie; Sun, Shui

    2015-01-01

    Objective: To investigate the efficacy and safety of tranexamic acid (TXA) injection during primary total knee arthroplasty (TKA) for reducing postoperative hemorrhage. Methods: 100 cases of patients admitted to our hospital and underwent primary unilateral TKA from January 2012 to December 2014 were enrolled in this study and they were divided randomly into two groups. For the TXA group, 1 g TXA was dissolved in 50 ml 0.9% sodium chloride solution and injected after prosthesis implantation but before cavity close. Conventional drainage clamping was carried for 4 h and the drainage tube was removed 48 h postoperative. For the control group, similar measures were taken except for that no TXA was dissolved in 0.9% sodium chloride solution. Postoperative hemoglobin, blood coagulation index, total blood loss volume, drainage volume, blood transfusion rate and lower extremity deep vein thrombosis (DVT) rate in both groups were observed and the efficacy and safety of this surgical treatment were evaluated. Results: There were no significant differences in operation time, postoperative platelet and APPT, D-dimer, lower limb venous thrombosis incidence rate 1 week after operation between the two groups. Postoperative drainage volume, hemoglobin, total blood loss and blood transfusion rate in the TXA group were significantly lower than those of the control group. Ecchymosis of lower extremity peripheral incision and its surroundings was significantly milder than that of the control group. Conclusion: Intraoperative intra-articular injection of TXA in TKA can significantly reduce the initial postoperative hemorrhage and blood transfusion rate at the early stage after operation. PMID:26550418

  13. Intra-Operative Inspired Fraction of Oxygen and the Risk of Surgical Site Infections in Patients with Type 1 Surgical Incisions.

    Science.gov (United States)

    Wanta, Brendan T; Hanson, Kristine T; Hyder, Joseph A; Stewart, Thomas M; Curry, Timothy B; Berbari, Elie F; Habermann, Elizabeth B; Kor, Daryl J; Brown, Michael J

    2018-04-02

    Whether the fraction of inspired oxygen (F I O 2 ) influences the risk of surgical site infection (SSI) is controversial. The World Health Organization and the World Federation of Societies of Anesthesiologists offer conflicting recommendations. In this study, we evaluate simultaneously three different definitions of F I O 2 exposure and the risk of SSI in a large surgical population. Patients with clean (type 1) surgical incisions who developed superficial and deep organ/space SSI within 30 days after surgery from January 2003 through December 2012 in five surgical specialties were matched to specialty-specific controls. Fraction of inspired oxygen exposure was defined as (1) nadir F I O 2 , (2) percentage of operative time with F I O 2 greater than 50%, and (3) cumulative hyperoxia exposure, calculated as the area under the curve (AUC) of F I O 2 by time for the duration in which F I O 2 greater than 50%. Stratified univariable and multivariable logistic regression models tested associations between F I O 2 and SSI. One thousand two hundred fifty cases of SSI were matched to 3,248 controls. Increased oxygen exposure, by any of the three measures, was not associated with the outcome of any SSI in a multivariable logistic regression model. Elevated body mass index (BMI; 35+ vs. operative oxygen exposure was associated with higher odds of SSI in the neurosurgical and spine populations. Increased intra-operative inspired fraction of oxygen was not associated with a reduction in SSI. These findings do not support the practice of increasing F I O 2 for the purpose of SSI reduction in patients with clean surgical incisions.

  14. Occupational radiation exposure to anesthetists from fluoroscopic projections during orthopedic operative procedures.

    Science.gov (United States)

    Abas, A A; Rahman, R A; Yahya, N; Kamaruzaman, E; Zainuddin, K; Manap, N A

    2014-01-01

    The role of anesthetists during orthopedic fluoroscopic procedures exposes them to radiation. We conducted a prospective, descriptive study to estimate the radiation exposure to anesthetists during procedures over a six-month period in the orthopedic trauma operating theatres which had the most fluoroscopic usage. Thermoluminescent dosimeter (TLD) chips were placed two metres away from the radiation source, in three positions to simulate the anesthetist's position in the operating theatre during the fluoroscopic procedures as well as their radiation safety practices. The three positions were above the lead gown, behind the lead gown and behind the protective lead screen. The fourth TLD chip was assigned as a control measure to account for background radiation. The radiation exposure was measured at every end of each month during the period of six consecutive months. The TLD chips were sent to the Malaysian Institute for Nuclear Technology (MINT) for the analysis. From the study, the annual exposure without a protective shield at a 2 metre distance from the projection source was estimated to be 0.70 milliSievert (mSv)/year. With the use of lead gowns and protective lead screens, the annual exposure was estimated to be 0.08 mSv / year. All the radiation levels measured were within the maximum permissible dose of 50 mSv / year. During fluoroscopic assisted orthopedic procedures, the anesthetists in UKMMC are exposed to a small amount of radiation which is well below the annual maximum permissible limit as determined by local and international regulatory bodies.

  15. Is post-operative radiation for renal cell carcinoma justified?

    International Nuclear Information System (INIS)

    Aref, Ibrahim; Bociek, R. Gregory; Salhani, Douglas

    1997-01-01

    Purpose: To identify the pattern of failure in patients with resected renal cell carcinoma (RCC). Materials and methods: The records of 116 patients with unilateral, non-hematogenous metastatic RCC who were treated with definitive surgery and referred to the Ottawa Regional Cancer Centre between 1977 and 1988 were reviewed. Distribution by stage included T1 (3 patients), T2 (42 patients) and T3 (71 patients). The median follow-up was 44 months, with a range of 4-267 months. Results: Local regional failure (LRF) developed in 8 patients. Nine patients developed local or regional recurrence, plus distant failure. Fifty-eight patients had distant metastases (DM) only. The 7-year actuarial rate for LRF and DM were 12%, and 67%, respectively. The overall 7-year actuarial survival rate was 35%, and cause-specific survival was 42%. Conclusions: LRF alone is rare following nephrectomy. DM is the main pattern of failure. This data does not support the role of adjuvant radiation therapy in this disease

  16. The effect of post-traumatic-stress-disorder on intra-operative analgesia in a veteran population during cataract procedures carried out using retrobulbar or topical anesthesia: a retrospective study.

    Science.gov (United States)

    Rapoport, Yuna; Wayman, Laura L; Chomsky, Amy S

    2017-06-07

    A growing proportion of veterans treated at the Veterans Health Administration (VA) have a history of post-traumatic-stress-disorder (PTSD), and there exists a higher rate of PTSD amongst veterans than the general population. The purpose of this study is to determine the correlation between PTSD and intra-operative analgesia, intra-operative time, and anesthesia type for cataract surgery in a veteran population. Secondary objectives are to determine if patient age, and first or second eye surgery affect intra-operative pain control or are correlated with type of anesthesia modality. A retrospective study of 330 cataract surgeries performed by resident physicians between January and September 2012 at the Veterans Affairs Medical Center Tennessee Valley Healthcare System, Nashville and Murfreesboro Campuses was completed. Three hundred and thirty veteran patients were selected if their cataract surgery was performed between January and September 2012. Combined cases were excluded. The primary outcome evaluated was intra-operative analgesia. Secondary outcomes included history of post-traumatic-stress-disorder, anesthesia type, first or second eye, pain control, intra-operative heart rate and blood pressure, age, and case complexity. Data was analyzed using an unpaired two-sample Welch's t-test assuming unequal variance and Z test of comparison of proportions. Patients with post-traumatic-stress-disorder reported higher pain scores, had longer operative times, and were more likely to have received a retrobulbar block. Operative time was not associated with an increased pain score, irrespective of anesthesia type, when controlled for PTSD. Complex cases had longer operative times, more sedation, and higher pain scores. P Post-traumatic stress disorder and anxiety are more prevalent in the veteran population. Our data suggests that a history of post-traumatic-stress-disorder was correlated with higher pain scores, longer operative times, and with having received a

  17. Intra-operative defibrillation testing and clinical shock efficacy in patients with implantable cardioverter-defibrillators: the NORDIC ICD randomized clinical trial.

    Science.gov (United States)

    Bänsch, Dietmar; Bonnemeier, Hendrik; Brandt, Johan; Bode, Frank; Svendsen, Jesper Hastrup; Táborský, Miloš; Kuster, Stefan; Blomström-Lundqvist, Carina; Felk, Angelika; Hauser, Tino; Suling, Anna; Wegscheider, Karl

    2015-10-01

    This trial was designed to test the hypothesis that shock efficacy during follow-up is not impaired in patients implanted without defibrillation (DF) testing during first implantable cardioverter-defibrillator (ICD) implantation. Between February 2011 and July 2013, 1077 patients were randomly assigned (1 : 1) to first time ICD implantation with (n = 540) or without (n = 537) DF testing. The intra-operative DF testing was standardized across all participating centres, and all ICD shocks were programmed to 40 J irrespective of DF test results. The primary end point was the average first shock efficacy (FSE) for all true ventricular tachycardia and fibrillation (VT/VF) episodes during follow-up. The secondary end points included procedural data, serious adverse events, and mortality. During a median follow-up of 22.8 months, the model-based FSE was found to be non-inferior in patients with an ICD implanted without a DF test, with a difference in FSE of 3.0% in favour of the no DF test [confidence interval (CI) -3.0 to 9.0%, Pnon-inferiority Defibrillation efficacy during follow-up is not inferior in patients with a 40 J ICD implanted without DF testing. Defibrillation testing during first time ICD implantation should no longer be recommended for routine left-sided ICD implantation. © The Author 2015. Published by Oxford University Press on behalf of the European Society of Cardiology.

  18. Radio Frequency Radiation (RFR) measurements in operational settings

    Science.gov (United States)

    Graham, R. B.

    1985-03-01

    A detailed discussion of the principles, procedures, and instrumentation required to carry out routine RFR measurements under field or operational conditions is presented. The information herein contained comes largely from several years of experience gathered by the USAF Occupational and Environmental Health Laboratory (USAF OEHL) and its predecessor the USAF Radiological Health Laboratory (USAF RHL). Over the last 12 years the USAF OEHL have evaluated and field tested a wide variety of RFR power density instrumentation designed, developed and manufactured by a number of firms and agencies. Each of these instruments has some outstanding characteristics and some equally poor features. Based on a number of years of experience only about 15% of the RFR emitters account for about 95% of the measurement problems. There are a number of classes of emitters that may be easily and promptly dismissed from consideration as a potential hazard to personnel.

  19. Effect of radiation damage on operating safety of steel pressure vessels of nuclear reactors

    International Nuclear Information System (INIS)

    Vacek, M.; Havel, S.; Stoces, B.; Brumovsky, M.

    1980-01-01

    The effects are assessed of the environment upon mechanical properties of steel used generally for pressure vessels of light water nuclear reactors. Changes caused by radiation affect the reliability of vessels. Deterioration of steel properties is mainly due to neutron radiation. The article deals with factors bearing upon damage and with methods allowing to evaluate the reliability of vessels and predict their service life. Operating reliability of vessels is very unfavourably affected by planned and accidental reactor transients. (author)

  20. Experiences with the operational radiation protection in the mine of Key Lake (Canada) and Forstau (Austria)

    International Nuclear Information System (INIS)

    Lindstroem, B.

    1978-01-01

    To control exposure to radiation all mining operations, e.g. in Key Lake, consisting of mine, processing, auxiliary plants and offices, are divided by the safety engineer into 'workplaces'. One or more monitoring devices are at each workplace. The frequency of measurements depends on the activity and its fluctuation. Besides the individual personal dosimetry which is made with film dosimeters, the β/γ-radiation is measured by highly sensitive dosimeters with digital display. (orig.) 891 HP/orig. 892 MB [de

  1. Dual phase helical CT versus portal venous phase CT for the detection of colorectal liver metastases: Correlation with intra-operative sonography, surgical and pathological findings

    Energy Technology Data Exchange (ETDEWEB)

    Scott, D. John; Guthrie, J. Ashley; Arnold, Paul; Ward, Janice; Atchley, Julian; Wilson, Daniel; Robinson, Philip J

    2001-03-01

    AIM: To assess whether dual phase helical computed tomography (DPCT) of the liver improves the detection of colorectal liver metastases compared with portal venous phase (PVP) imaging alone. MATERIALS AND METHODS: DPCT was performed in 33 consecutive patients before laparotomy for resection of colorectal liver metastases. CT comprised 8-mm slice collimation with a pitch of 1 to 1.25; imaging was commenced 20-25 and 65-70 s after the start of injection of 150 ml of contrast medium at 5 ml/s to coincide with hepatic arterial phase (HAP) and PVP contrast enhancement, respectively. Four blinded observers independently reviewed the HAP, PVP and DPCT images recording the site and size of all lesions. Alternative-free response receiver operating characteristic (AFROC) methodology was used to analyse the results, which were correlated with surgery, intra-operative ultrasound and histology. RESULTS: The mean observer sensitivities for malignant lesion detection were 75.3% for DPCT, 69.7% for PVP imaging and 66.7% for HAP imaging alone. There was a statistically significant improvement in malignant lesion detection using DPCT when compared with PVP imaging alone (P < 0.05). The mean areas under the AFROC curves were 0.84 for DPCT and 0.82 for PVP (P < 0.03) imaging alone. CONCLUSION: The detection of colorectal liver metastases was marginally better with DPCT than with PVP imaging alone, but the discovery of additional lesions did not affect the management of any of the patients in this study. Scott, D.J. et al. (2001)

  2. Dual phase helical CT versus portal venous phase CT for the detection of colorectal liver metastases: Correlation with intra-operative sonography, surgical and pathological findings

    International Nuclear Information System (INIS)

    Scott, D. John; Guthrie, J. Ashley; Arnold, Paul; Ward, Janice; Atchley, Julian; Wilson, Daniel; Robinson, Philip J.

    2001-01-01

    AIM: To assess whether dual phase helical computed tomography (DPCT) of the liver improves the detection of colorectal liver metastases compared with portal venous phase (PVP) imaging alone. MATERIALS AND METHODS: DPCT was performed in 33 consecutive patients before laparotomy for resection of colorectal liver metastases. CT comprised 8-mm slice collimation with a pitch of 1 to 1.25; imaging was commenced 20-25 and 65-70 s after the start of injection of 150 ml of contrast medium at 5 ml/s to coincide with hepatic arterial phase (HAP) and PVP contrast enhancement, respectively. Four blinded observers independently reviewed the HAP, PVP and DPCT images recording the site and size of all lesions. Alternative-free response receiver operating characteristic (AFROC) methodology was used to analyse the results, which were correlated with surgery, intra-operative ultrasound and histology. RESULTS: The mean observer sensitivities for malignant lesion detection were 75.3% for DPCT, 69.7% for PVP imaging and 66.7% for HAP imaging alone. There was a statistically significant improvement in malignant lesion detection using DPCT when compared with PVP imaging alone (P < 0.05). The mean areas under the AFROC curves were 0.84 for DPCT and 0.82 for PVP (P < 0.03) imaging alone. CONCLUSION: The detection of colorectal liver metastases was marginally better with DPCT than with PVP imaging alone, but the discovery of additional lesions did not affect the management of any of the patients in this study. Scott, D.J. et al. (2001)

  3. TFTR radiation contour and shielding efficiency measurements during D-D operations

    Energy Technology Data Exchange (ETDEWEB)

    Kugel, H.W.; Ascione, G.; Elwood, S.; Gilbert, J.; Hwang, D.; Lewis, M.; Levine, J.; Ku, L.P.; Rule, K. [Princeton Plasma Physics Lab., NJ (United States); Hajnal, F. [Department of Energy, New York, NY (United States)] [and others

    1994-11-01

    Extensive neutron and gamma radiation contour, shielding efficiency, and spectral measurements were performed during high power TFTR D-D operations at the tokamak Test Cell inner walls, ceiling, roof, and outer walls, in nearby control rooms, work areas, and personnel pathways, outdoors along the site fence at 125 m, and out to the nearest property lines at 180 m. The results confirmed that the efficiency of the basic radiation shielding was sufficient to allow the TFTR D-T experimental plan, and provide empirical guidance for simulating the radiation fields of future fusion reactors.

  4. Radiation safety analysis and action plans for NSRRC top-up operation

    International Nuclear Information System (INIS)

    Wang, J.-P.; Sheu, R.-J.; Liu, Joseph C.; Chen, C.-R.; Chang, F.-D.; Kao, S.-P.

    2006-01-01

    This paper summarizes the radiation safety analysis and action plans for the upcoming top-up operation at the National Synchrotron Radiation Research Center (NSRRC). Electron beam loss scenarios and consequence of beam lifetime and injection efficiency have been studied. Dose assessment was conducted based on measurement and Monte Carlo simulation results. Radiation safety action plans such as upgrading the shielding of the injection section, enlarging the exclusion zones of the straight section beamlines, installing new interlock system for top-up operation and most importantly improving the injection efficiency have been scheduled. The goal is to keep present dose limit of 2 mSv/y and make top-up operation feasible at normal user's run of year 2006

  5. Comparison of environmental radiation doses estimated for Hanford Operations, 1977 through 1982

    International Nuclear Information System (INIS)

    McCormack, W.D.; Carlile, J.M.V.; Peloquin, R.A.; Napier, B.A.

    1983-12-01

    Offsite environmental radiation dose equivalents based on Hanford operations are compared for the years 1977 through 1981 to those calculated for 1982. The comparison revealed a downward trend in calculated offsite doses over the period 1977 through 1982, due primarily to reported reduced effluent releases, changes in effluent reporting methods, and increased Columbia River flow over this period. The calculated doses verify the surveillance program findings that potential offsite radiation doses due to Hanford Operations are small and well below our ability to detect in the environment. 11 references, 23 tables

  6. Research Operator Protection Optimization by the Education and Training on Radiation Protection

    International Nuclear Information System (INIS)

    Mateos, J. C.; Avalos, J.; Garcia-Leon, M.; Garcia-Tenorio, R.; Gomez-Puerto, A.; Gomez, M.; Herrador, M.; Lejeune, J.; Luis-Simon, J.; Marquez, A.; Maranon, J.; Respaldiza, M. A.; Sanchez-Angulo, C.; Sanchez-Doblado, F.; Sarmiento, J. M.

    2004-01-01

    One of the best ways of protection to operators in any radiation practice is to provide him/her with an adequate level of education and training in radiation protection. There are many international references where this fact is pointed out and particularly it is recognized the importance of the introduction of radiation protection courses previously to their work with ionising radiation. The University of Sevilla (Spain) through its Radioisotope Service has been organizing biannually since 1995 Training Courses for Supervisors and Operators of Radioactive Installations for university investigators that use radioactive sources or radiation equipment. The courses are imparted by teachers from the university radioactive installations, hospital physicist specialists from medical physics services and medical doctors from prevention labour health service; all of them are the authors of this communication. The students are postgraduate students or teachers that need operate with ionising radiation in their research laboratories. Up to date, it has been organized 4 courses series with an average of 30 students per course. These courses are homologated by the Nuclear Security Council and let the student obtain the licence for Supervisors or Operators of Radioactive Installations in each of the following applications fields: a) Laboratories with Non-Encapsulated Sources. This application includes research activities in Biology, Chemistry, Physics, Medicine and Pharmacy. b) Radiation Generator Equipment. This last one includes equipment such as X-Rays apparatus for diffraction studies in physics, chemistry and art sciences, or Particle Accelerator for atomic physics research in the National Accelerator Centre. The practical sessions of the courses are imparted in the radioactive installations of the Seville university. In this study it is described the details of the organization of the courses. (Author)

  7. The effects of ionizing radiation on commercial power MOSFETs operated at cryogenic temperatures

    International Nuclear Information System (INIS)

    Johnson, G.H.; Kemp, W.T.; Ackermann, M.R.; Pugh, R.D.; Schrimpf, R.D.; Galloway, K.F.

    1994-01-01

    This is the first report of commercial n- and p-channel power MOSFETs exposed to ionizing radiation while operating in a cryogenic environment. The transistors were exposed to low energy x-rays while placed in a liquid nitrogen-cooled dewar. Results demonstrate significant performance and survivability advantages for space-borne power MOSFETs operated at cryogenic temperatures. The key advantages for low-temperature operation of power MOSFET's in an ionizing radiation environment are: (1) steeper subthreshold current slope before and after irradiation; (2) lower off-state leakage currents before and after irradiation; and (3) larger prerad threshold voltage for n-channel devices. The first two points are also beneficial for devices that are not irradiated, but the advantages are more significant in radiation environments. The third point is only an advantage for commercial devices operated in radiation environments. Results also demonstrate that commercial off-the-shelf power MOSFETs can be used for low-temperature operations in a limited total dose environment (i.e., many space applications)

  8. Operation of the ATLAS Transition Radiation Tracker under very high irradiation at the CERN LHC

    Science.gov (United States)

    Akesson, T.; Arik, E.; Baker, K.; Baron, S.; Benjamin, D.; Bertelsen, H.; Bondarenko, V.; Bytchkov, V.; Callahan, J.; Capeans, M.; Cardiel-Sas, L.; Catinaccio, A.; Cetin, S. A.; Cwetanski, P.; Dam, M.; Danielsson, H.; Dittus, F.; Dolgoshein, B.; Dressnandt, N.; Driouichi, C.; Ebenstein, W. L.; Eerola, P.; Farthouat, P.; Fedin, O.; Froidevaux, D.; Gagnon, P.; Grichkevitch, Y.; Grigalashvili, N.; Hajduk, Z.; Hansen, P.; Kayumov, F.; Keener, P. T.; Kekelidze, G.; Khristatchev, A.; Konovalov, S.; Koudine, L.; Kovalenko, S.; Kowalski, T.; Kramarenko, V. A.; Kruger, K.; Laritchev, A.; Lichard, P.; Luehring, F.; Lundberg, B.; Maleev, V.; McFarlane, K.; Mialkovski, V.; Mindur, B.; Mitsou, V. A.; Morozov, S.; Munar, A.; Muraviev, S.; Nadtochy, A.; Newcomer, F. M.; Ogren, H.; Oh, S. H.; Oleshko, S.; Olszowska, J.; Passmore, S.; Patritchev, S.; Peshekhonov, V.; Petti, R.; Price, M.; Rembser, C.; Rohne, O.; Romaniouk, A.; Rust, D. R.; Ryabov, Yu.; Schegelsky, V.; Seliverstov, D.; Shin, T.; Shmeleva, A.; Smirnov, S.; Sosnovtsev, V.; Soutchkov, V.; Spiridenkov, E.; Tikhomirov, V.; Van Berg, R.; Vassilakopoulos, V.; Vassilieva, L.; Wang, C.; Williams, H. H.; Zalite, A.

    2004-04-01

    The ATLAS Transition Radiation Tracker (TRT) performance depends critically on the choice of the active gas and on its properties. The most important operational aspects, which have led to the final choice of the active gas for the operation of the TRT at the LHC design luminosity, are presented. The TRT performance expected at these conditions is reviewed, including pile-up effects at high luminosity.

  9. Comparison of surgical outcomes after anterior cervical discectomy and fusion: does the intra-operative use of a microscope improve surgical outcomes.

    Science.gov (United States)

    Adogwa, Owoicho; Elsamadicy, Aladine; Reiser, Elizabeth; Ziegler, Cole; Freischlag, Kyle; Cheng, Joseph; Bagley, Carlos A

    2016-03-01

    The primary aim of this study was to assess and compare the complications profile as well as long-term clinical outcomes between patients undergoing an Anterior Cervical Discectomy and Fusion (ACDF) procedure with and without the use of an intra-operative microscope. One hundred and forty adult patients (non-microscope cohort: 81; microscope cohort: 59) undergoing ACDF at a major academic medical center were included in this study. Enrollment criteria included available demographic, surgical and clinical outcome data. All patients had prospectively collected patient-reported outcomes measures and a minimum 2-year follow-up. Patients completed the neck disability index (NDI), short-form 12 (SF-12) and visual analog pain scale (VAS) before surgery, then at 3, 6, 12, and 24 months after surgery. Clinical outcomes and complication rates were compared between both patient cohorts. Baseline characteristics were similar between both cohorts. The mean ± standard deviation duration of surgery was longer in the microscope cohort (microscope: 169±34 minutes vs. non-microscope: 98±42 minutes, Pmicroscope and non-microscope cohorts demonstrated similar improvement from base line in NDI (microscope: 13.52±25.77 vs. non-microscope: 19.51±27.47, Pmicroscope: 4.15±26.39 vs. non-microscope: 11.98±22.96, Pmicroscope: 9.47±32.38 vs. non-microscope: 16.19±30.44, Pmicroscope: 2.22±4.00 vs. non-microscope: 3.69±3.61, Pmicroscope does not improve overall surgery-related outcomes, nor does it lead to superior long-term outcomes in pain and functional disability, 2 years after index surgery.

  10. Simultaneous multi-scale microscopy as a potential dedicated tool for intra-operative parathyroid identification during thyroid surgery (Conference Presentation)

    Science.gov (United States)

    De Montigny, Étienne; Goulamhoussen, Nadir; Madore, Wendy-Julie; Strupler, Mathias; Maniakas, Anastasios; Ayad, Tareck; Boudoux, Caroline

    2016-02-01

    While thyroidectomy is considered a safe surgery, dedicated tools facilitating tissue identification during surgery could improve its outcome. The most common complication following surgery is hypocalcaemia, which results from iatrogenic removal or damage to parathyroid glands. This research project aims at developing and validating an instrument based on optical microscopy modalities to identify tissues in real time during surgery. Our approach is based on a combination of reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) to obtain multi-scale morphological contrast images. The orthogonal field of views provide information to navigate through the sample. To allow simultaneous, synchronized video-rate imaging in both modalities, we designed and built a dual-band wavelength-swept laser which scans a 30 nm band centered at 780 nm and a 90 nm band centered at 1310 nm. We built an imaging setup integrating a custom-made objective lens and a double-clad fibre coupler optimized for confocal microscopy. It features high resolutions in RCM (2µm lateral and 20 µm axial) in a 500 µm x 500 µm field-of-view and a larger field-of-view of 2 mm (lateral) x 5 mm (axial) with 20 µm lateral and axial resolutions in OCT. Imaging of ex vivo animal samples is demonstrated on a bench-top system. Tissues that are visually difficult to distinguish from each other intra-operatively such as parathyroid gland, lymph nodes and adipose tissue are imaged to show the potential of this approach in differentiating neck tissues. We will also provide an update on our ongoing clinical pilot study on patients undergoing thyroidectomy.

  11. Absorbed doses and radiation damage during the 11 years of LEP operation

    CERN Document Server

    Schönbacher, H

    2004-01-01

    During the 11 years of operation of the Large Electron Positron Collider (LEP), synchrotron radiation was emitted in the tunnel. This ionizing radiation induced degradation in organic insulators and structural materials, as well as in electronics. Annual dosimetric measurements have shown that the level of radiation increased with the ninth power of the beam energy. During the machine shut-downs and at the end of the operation, samples of rigid and flexible polymeric insulators (magnet-coil resins and cable insulations) were taken out and checked for their integrity. The test results are compared with the results obtained during the qualification of the materials, 12 to 15 years ago. At that time, lifetime predictions were done; they are now compared with the real time aged materials.

  12. Radiation dose estimates due to air particulate emissions from selected phosphate industry operations

    International Nuclear Information System (INIS)

    Partridge, J.E.; Horton, T.R.; Sensintaffar, E.L.; Boysen, G.A.

    1978-06-01

    The EPA Office of Radiation Programs has conducted a series of studies to determine the radiological impact of the phosphate mining and milling industry. This report describes the efforts to estimate the radiation doses due to airborne emissions of particulates from selected phosphate milling operations in Florida. Two wet process phosphoric acid plants and one ore drying facility were selected for this study. The 1976 Annual Operations/Emissions Report, submitted by each facility to the Florida Department of Environmental Regulation, and a field survey trip by EPA personnel to each facility were used to develop data for dose calculations. The field survey trip included sampling for stack emissions and ambient air samples collected in the general vicinity of each plant. Population and individual radiation dose estimates are made based on these sources of data

  13. Radiation dose evaluation based on exposure scenario during the operation of radioactive waste disposal facility

    International Nuclear Information System (INIS)

    Yoon, Jeong Hyoun; Kim Chang Lak; Choi, Heui Joo; Park, Joo Wan

    1999-01-01

    Radiation dose to worker in disposal facility was calculated by using point kernel MICROSHIELD V5.02 computer code based on exposure scenarios. An conceptual design model for disposal vaults in disposal facility was used for object of shielding calculation model. Selected radionuclides and their activities among radioactive wastes from nuclear power plants were assumed as radiation sources for the exposure calculation. Annual radiation doses to crane workers and to people working on disposal vaults were calculated according to exposure time and distance from the sources with conservative operation scenarios. The scenarios used for this study were based on assumption for representing disposal activities in a future Korean near surface disposal facility. Calculated exposure rates to worker during normal disposal work were very low comparing with annual allowable limit for radiation worker

  14. Automation of metrological operations on measuring apparatuses of radiation monitoring system

    International Nuclear Information System (INIS)

    Kulich, V.; Studeny, J.

    1995-01-01

    (J.K.)In this paper the measuring apparatuses of ionizing radiation for the radiation monitoring of NPP Dukovany operation is described. The increase of metrological operations number has been made possible only by a timely reconstruction of the laboratory and by computerization of the measuring procedure and of administrative work which consists mainly of recording of a great number information pieces about the observed measuring apparatuses. There are three working places in the laboratory: 1) irradiation gamma stand with cesium-137 sources; 2) irradiation stand with plutonium-beryllium neutron sources; 3) spectrometric working place. With the regard to the uniqueness of the laboratory operation, all the works in the sphere of hardware as well as software has been implemented by own forces. The equipment of the laboratory makes possible to test metrologically all the radiation monitoring apparatuses used in NPP Dukovany. The quantity of operation of he laboratory of ionizing metrology qualifies the proper functioning of the radiation monitoring system, which directly influences the ensurance of nuclear safety of NPP Dukovany

  15. Operating a Microwave Radiation Detection Monitor. Module 10. Vocational Education Training in Environmental Health Sciences.

    Science.gov (United States)

    Consumer Dynamics Inc., Rockville, MD.

    This module, one of 25 on vocational education training for careers in environmental health occupations, contains self-instructional materials on operating a microwave radiation detection monitor. Following guidelines for students and instructors and an introduction that explains what the student will learn are three lessons: (1) testing the…

  16. Sex differences in operant responding and survivability following exposure to space radiation

    Science.gov (United States)

    On exploratory class missions, such as a mission to Mars, astronauts will be exposed to types and doses of radiation (galactic cosmic rays [GCR]) which are not experienced in low earth orbit where the space shuttle and International Space Station operate. Despite the fact that the crew on such a mi...

  17. Incremental value of combined 99MTc tetrofosmin parathyroid scintigraphy, rapid intra operative PTH assays and minimally invasive radio-guided surgery (MIRS) in optimizing parathyroidectomies

    International Nuclear Information System (INIS)

    Padma, S.; Kumar, S.; Babu, T.; Kumar, H.; Nair, V.; Nair, G.K.

    2004-01-01

    Objective: Aim of our study was to evaluate incremental diagnostic value of 99mTc Tetrofosmin parathyroid SPECT (TPSPECT), rapid intra operative quick parathyroid hormone measurement (QPTH) combined with radio guidance provided by scintillation probe (Minimally Invasive Radio guided Surgery MIRS) in parathyroid surgeries. While TPSPECT is an established investigation in preoperative workup of hyperparathyroidism patients , MIRS is a relatively new concept in Indian subcontinent. Methods: 29 pts (M: F = 18: 11), age range 16- 65 yrs (mean 41+ 9 yrs) having clinical and biochemical hyperparathyroidism underwent TPSPECT between Jan 02 -04, using 20 mci IV 99mTc Tetrofosmin. Pts with familial hyperparathyroidism , previous nodular goiters and previous neck irradiation were excluded from study. Scintigraphy comprised of immediate, delayed planar and SPECT imaging of neck and chest. Imagewise abnormal, persistent tracer uptake was considered positive for adenoma and diffuse uptake for hyperplasia. 26 pts underwent exploration (22 adenomas and 4 hyperplasias).18 pts had benefit of intraoperative QPTH. A select group (after Dec 2003) i.e. 9 pts got the assistance of radioguided probing. Peroperatively NM physician used cordless handheld gamma probe (Gamma Finder, World of Medicine, Germany) in neck and mediastinum to detect parathyroid adenoma / hyperplasias. A five fold increase in radioactive counts perceived by probe when compared to background was considered positive for parathyroid adenoma / hyperplasia. If PTH levels fell from baseline by at least 50%, the surgery was concluded as complete. Results: In all 22 pts suspected to have primary hyperparathyroidism TPSPECT identified adenomas (100 % sensitivity). While planar imaging had a sensitivity of 90.1% (20/22 pts), SPECT identified the adenoma in all pts. Interestingly only 3/22 pts had ectopic glands while 5 had more than one adenomas. The most commonly involved gland was left inferior. In secondary

  18. Particle interaction and displacement damage in silicon devices operated in radiation environments

    International Nuclear Information System (INIS)

    Leroy, Claude; Rancoita, Pier-Giorgio

    2007-01-01

    Silicon is used in radiation detectors and electronic devices. Nowadays, these devices achieving submicron technology are parts of integrated circuits of large to very large scale integration (VLSI). Silicon and silicon-based devices are commonly operated in many fields including particle physics experiments, nuclear medicine and space. Some of these fields present adverse radiation environments that may affect the operation of the devices. The particle energy deposition mechanisms by ionization and non-ionization processes are reviewed as well as the radiation-induced damage and its effect on device parameters evolution, depending on particle type, energy and fluence. The temporary or permanent damage inflicted by a single particle (single event effect) to electronic devices or integrated circuits is treated separately from the total ionizing dose (TID) effect for which the accumulated fluence causes degradation and from the displacement damage induced by the non-ionizing energy-loss (NIEL) deposition. Understanding of radiation effects on silicon devices has an impact on their design and allows the prediction of a specific device behaviour when exposed to a radiation field of interest

  19. Occupational radiation exposure history of Idaho Field Office Operations at the INEL

    International Nuclear Information System (INIS)

    Horan, J.R.; Braun, J.B.

    1993-10-01

    An extensive review has been made of the occupational radiation exposure records of workers at the Idaho National Engineering Laboratory (INEL) over the period of 1951 through 1990. The focus has been on workers employed by contractors and employees of the Idaho Field Operations Office (ID) of the United States Department of Energy (USDOE) and does not include the Naval Reactors Facility (NRF), the Argonne National Laboratory (ANL), or other operations field offices at the INEL. The radiation protection guides have decreased from 15 rem/year to 5 rem/year in 1990 for whole body penetrating radiation exposure. During these 40 years of nuclear operations (in excess of 200,000 man-years of work), a total of twelve individuals involved in four accidents exceeded the annual guidelines for exposure; nine of these exposures were received during life saving efforts on January 3, 1961 following the SL-1 reactor accident which killed three military personnel. These exposures ranged from 8 to 27 rem. Only one individual has exceeded the annual whole body penetrating radiation protection guidelines in the last 29 years

  20. Occupational radiation exposure history of Idaho Field Office Operations at the INEL

    Energy Technology Data Exchange (ETDEWEB)

    Horan, J.R.; Braun, J.B.

    1993-10-01

    An extensive review has been made of the occupational radiation exposure records of workers at the Idaho National Engineering Laboratory (INEL) over the period of 1951 through 1990. The focus has been on workers employed by contractors and employees of the Idaho Field Operations Office (ID) of the United States Department of Energy (USDOE) and does not include the Naval Reactors Facility (NRF), the Argonne National Laboratory (ANL), or other operations field offices at the INEL. The radiation protection guides have decreased from 15 rem/year to 5 rem/year in 1990 for whole body penetrating radiation exposure. During these 40 years of nuclear operations (in excess of 200,000 man-years of work), a total of twelve individuals involved in four accidents exceeded the annual guidelines for exposure; nine of these exposures were received during life saving efforts on January 3, 1961 following the SL-1 reactor accident which killed three military personnel. These exposures ranged from 8 to 27 rem. Only one individual has exceeded the annual whole body penetrating radiation protection guidelines in the last 29 years.

  1. Radiative transfer solutions for coupled atmosphere ocean systems using the matrix operator technique

    International Nuclear Information System (INIS)

    Hollstein, André; Fischer, Jürgen

    2012-01-01

    Accurate radiative transfer models are the key tools for the understanding of radiative transfer processes in the atmosphere and ocean, and for the development of remote sensing algorithms. The widely used scalar approximation of radiative transfer can lead to errors in calculated top of atmosphere radiances. We show results with errors in the order of±8% for atmosphere ocean systems with case one waters. Variations in sea water salinity and temperature can lead to variations in the signal of similar magnitude. Therefore, we enhanced our scalar radiative transfer model MOMO, which is in use at Freie Universität Berlin, to treat these effects as accurately as possible. We describe our one-dimensional vector radiative transfer model for an atmosphere ocean system with a rough interface. We describe the matrix operator scheme and the bio-optical model for case one waters. We discuss some effects of neglecting polarization in radiative transfer calculations and effects of salinity changes for top of atmosphere radiances. Results are shown for the channels of the satellite instruments MERIS and OLCI from 412.5 nm to 900 nm.

  2. Investigation on Main Radiation Source at Operation Floor of Fukushima Daiichi Nuclear Power Station Unit 4

    Science.gov (United States)

    Hirayama, Hideo; Kondo, Kenjiro; Suzuki, Seishiro; Hamamoto, Shimpei; Iwanaga, Kohei

    2017-09-01

    Pulse height distributions were measured using a LaBr3 detector set in a 1 cm lead collimator to investigate main radiation source at the operation floor of Fukushima Daiichi Nuclear Power Station Unit 4. It was confirmed that main radiation source above the reactor well was Co-60 from the activated steam dryer in the DS pool (Dryer-Separator pool) and that at the standby area was Cs-134 and Cs-137 from contaminated buildings and debris at the lower floor. Full energy peak count rate of Co-60 was reduced about 1/3 by 12mm lead sheet placed on the floor of the fuel handling machine.

  3. High-dose-rate intra-cavitary brachytherapy combined with external beam radiation therapy for under 40-year-old patients with invasive uterine cervical carcinoma. Clinical outcomes in 118 patients in a Japanese multi-institutional study, JASTRO

    International Nuclear Information System (INIS)

    Yamashita, Hideomi; Niibe, Yuzuru; Toita, Takafumi

    2013-01-01

    The current study was designed to evaluate the clinical outcomes of curative intent radiation therapy for young patients with invasive uterine cervical carcinoma in Japan. One hundred and eighteen patients aged ≤40 were registered in the multi-institutional study of the Japanese Society of Therapeutic Radiology and Oncology (JASTRO) from 26 major institutions in Japan. The age range was 24-39 years and the maximum tumor diameter was 2.0-9.2 cm. The International Federation of Gynecology and Obstetrics clinical stages were Ib, IIa, IIb, IIIa, IIIb and IVa in 17, 6, 40, 2, 50 and 3, respectively. Curative intent radiation therapy consisted of the combination of external beam radiation therapy and high-dose rate intra-cavitary brachytherapy. The total dose of external beam radiation therapy ranged between 44 and 68 Gy. Both the median and mode of total high-dose-rate intra-cavitary brachytherapy dose to point A were 24 Gy in four fractions. Ninety-six patients (58%) received chemotherapy. The 5-year overall survival rate and local control rate of all patients were 61 and 65%, respectively. The 5-year overall survival rates of International Federation of Gynecology and Obstetrics Stage Ib, IIa, IIb, IIIa, IIIb and IVa were 88, 100, 75, 100, 37 and 0%, respectively. The 5-year local control rates of International Federation of Gynecology and Obstetrics Stage Ib, IIa, IIb, IIIa, IIIb and IVa were 82, 75, 75, 100, 51 and 0%, respectively. Sixteen patients experienced grade 3 or greater late radiation morbidity. The 5-year overall survival rate of young patients with Stage IIIb was comparatively low at 37%. (author)

  4. Fracture Surgery of the extremities with the intra-operative use of 3D-RX: A randomized multicenter trial (EF3X-trial)

    NARCIS (Netherlands)

    Beerekamp, M.S.H.; Ubbink, D.T.; Maas, M.; Luitse, J.S.K.; Kloen, P.; Blokhuis, T.J.M.; Segers, M.J.M.; Marmor, M.; Schep, N.W.L.; Dijkgraaf, M.G.W.; Goslings, J.C.; Ef3x-Trial, P.G.

    2011-01-01

    ABSTRACT: BACKGROUND: Posttraumatic osteoarthritis can develop after an intra-articular extremity fracture, leading to pain and loss of function. According to international guidelines, anatomical reduction and fixation are the basis for an optimal functional result. In order to achieve this during

  5. Fracture surgery of the extremities with the intra-operative use of 3D-RX: a randomized multicenter trial (EF3X-trial)

    NARCIS (Netherlands)

    Beerekamp, M. Suzan H.; Ubbink, Dirk Th; Maas, Mario; Luitse, Jan Sk; Kloen, Peter; Blokhuis, Taco Jm; Segers, Michiel Jm; Marmor, Meir; Schep, Niels Wl; Dijkgraaf, Marcel Gw; Goslings, J. Carel

    2011-01-01

    Posttraumatic osteoarthritis can develop after an intra-articular extremity fracture, leading to pain and loss of function. According to international guidelines, anatomical reduction and fixation are the basis for an optimal functional result. In order to achieve this during fracture surgery, an

  6. Tight intra-operative blood pressure control versus standard care for patients undergoing hip fracture repair - Hip Fracture Intervention Study for Prevention of Hypotension (HIP-HOP) trial: study protocol for a randomised controlled trial.

    Science.gov (United States)

    Moppett, Iain Keith; White, Stuart; Griffiths, Richard; Buggy, Donal

    2017-07-25

    Hypotension during anaesthesia for hip fracture surgery is common. Recent data suggest that there is an association between the lowest intra-operative blood pressure and mortality, even when adjusted for co-morbidities. This is consistent with data derived from the wider surgical population, where magnitude and duration of hypotension are associated with mortality and peri-operative complications. However, there are no trial to data to support more aggressive blood pressure control. We are conducting a three-centre, randomised, double-blinded pilot study in three hospitals in the United Kingdom. The sample size will be 75 patients (25 from each centre). Randomisation will be done using computer-generated concealed tables. Both participants and investigators will be blinded to group allocation. Participants will be aged >70 years, cognitively intact (Abbreviated Mental Test Score 7 or greater), able to give informed consent and admitted directly through the emergency department with a fractured neck of the femur requiring operative repair. Patients randomised to tight blood pressure control or avoidance of intra-operative hypotension will receive active treatment as required to maintain both of the following: systolic arterial blood pressure >80% of baseline pre-operative value and mean arterial pressure >75 mmHg throughout. All participants will receive standard hospital care, including spinal or general anaesthesia, at the discretion of the clinical team. The primary outcome is a composite of the presence or absence of defined cardiovascular, renal and delirium morbidity within 7 days of surgery (myocardial injury, stroke, acute kidney injury, delirium). Secondary endpoints will include the defined individual morbidities, mortality, early mobility and discharge to usual residence. This is a small-scale pilot study investigating the feasibility of a trial of tight intra-operative blood pressure control in a frail elderly patient group with known high morbidity

  7. A boiling-water reactor concept for low radiation exposure based on operating experience

    International Nuclear Information System (INIS)

    Koine, Y.; Uchida, S.; Izumiya, M.; Miki, M.

    1983-01-01

    A review of boiling-water reactor (BWR) operating experience indicates the significant role of water chemistry in determining the radiation dose rate contributing to occupational exposure. The major contributor among the radioactive species involved is identified as 60 Co, produced by neutron activation of 59 Co originating from structural materials. Iron crud, a fine solid form of corrosion product in the reactor water, is also shown to enhance the radiation dose rate. A theoretical study, supported by the operating experience and an extensive confirmatory test, led to the computerized analytical model called DR CRUD which is capable of predicting long-term radiation dose buildup. It accounts for the mechanism of radiation buildup through corrosion products such as irons, cobalts and other radioactive elements; their generation, transport, activation, interaction and deposition in the reactor coolant system are simulated. A scoping analysis, using this model as a tool, establishes the base line of the BWR concept for low occupational exposure. The base line consists of a set of target values for an annual exposure of 200 man.rem in an 1100 MW(e) BWR unit. They are the parameters that will be built into the design such as iron and cobalt inputs to the reactor water, and the capability of the reactor and the condensate purification system. Applicable means of technology are identified to meet the targets, ranging from improved water chemistry to the purification technique, optimized material selection and the recommended operational procedure. Extensive test programmes provide specifications of these means for use in BWRs. Combinations of their application are reviewed to define the concept of reduced exposure. Analytical study verifies the effectiveness of the proposed BWR concept in achieving a low radiation dose rate; occupational exposure is reduced to 200 man.rem/a. (author)

  8. Radiation protection cabin for catheter-directed liver interventions: operator dose assessment

    International Nuclear Information System (INIS)

    Maleux, Geert; Bosmans, Hilde; Bergans, Niki; Bogaerts, Ria

    2016-01-01

    The number and complexity of interventional radiological procedures and in particular catheter-directed liver interventions have increased substantially. The current study investigates the reduction of personal doses when using a dedicated radiation protection cabin (RPC) for these procedures. Operator and assistant doses were assessed for 3 series of 20 chemo-infusion/chemoembolisation interventions, including an equal number of procedures with and without RPC. Whole body doses, finger doses and doses at the level of knees and eyes were evaluated with different types of TLD-100 Harshaw dosemeters. Dosemeters were also attached on the three walls of the RPC. The operator doses were significantly reduced by the RPC, but also without RPC, the doses appear to be limited as a result of thorough optimisation with existing radiation protection tools. The added value of the RPC should thus be determined by the outcome of balancing dose reduction and other aspects such as ergonomic benefits. (authors)

  9. Operational Radiation Protection in Synchrotron Light and Free Electron Laser Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Liu, James C.; Rokni, Sayed H.; /SLAC; Vylet, Vaclav; /Jefferson Lab

    2009-12-11

    The 3rd generation synchrotron radiation (SR) facilities are storage ring based facilities with many insertion devices and photon beamlines, and have low injection beam power (< few tens of watts), but extremely high stored beam power ({approx} 1 GW). The 4th generation x-ray free electron laser (FEL) facilities are based on an electron Linac with a long undulator and have high injection beam power (a few kW). Due to its electron and photon beam characteristics and modes of operation, storage ring and photon beamlines have unique safety aspects, which are the main subjects of this paper. The shielding design limits, operational modes, and beam losses are first reviewed. Shielding analysis (source terms and methodologies) and interlocked safety systems for storage ring and photon beamlines (including SR and gas bremsstrahlung) are described. Specific safety issues for storage ring top-off injection operation and FEL facilities are discussed. The operational safety program, e.g., operation authorization, commissioning, training, and radiation measurements, for SR facilities is also presented.

  10. Development of Logistics for Building Radiation Storm Shelters and Their Operational Evaluation

    Science.gov (United States)

    Cerro, Jeffrey A.

    2015-01-01

    Over the past three years NASA has been studying the operational effectiveness and astronaut protection efficacy of numerous radiation protection shelters for use in space exploration activities outside of earth's magnetosphere. The work presented was part of NASA's Advanced Exploration Systems (AES) RadWorks Storm Shelter project. This paper is a summary of the concept development activities of this third year. Fabricated items were integrated into mock up deep space habitat vehicle sections for operational evaluations. Two full scale human-in-loop simulations were designed, fabricated, and implemented through an Institutional Review Board approved solicited participant assessment process. Fabricated items are described, along with usage scenarios of two protection approaches. Existing ISS type logistics along with proposed variations of those logistics were used. Preliminary Discrete Event Simulation (DES) work is noted to be useful in quantifying and documenting operational performance measures for the two primary shelter methods, including some characterization of radiation dose accumulation over a mission timeline. The project also performed correlation analyses between effective radiation dose and the Risk of Exposure Induced Death (REID) to show that concept level work may be able to include such a performance metric in early stages of mission scenario habitat design trade space investigation.

  11. Transfer of Real-time Dynamic Radiation Environment Assimilation Model; Research to Operation

    Science.gov (United States)

    Cho, K. S. F.; Hwang, J.; Shin, D. K.; Kim, G. J.; Morley, S.; Henderson, M. G.; Friedel, R. H.; Reeves, G. D.

    2015-12-01

    Real-time Dynamic Radiation Environment Assimilation Model (rtDREAM) was developed by LANL for nowcast of energetic electrons' flux at the radiation belt to quantify potential risks from radiation damage at the satellites. Assimilated data are from multiple sources including LANL assets (GEO, GPS). For transfer from research to operation of the rtDREAM code, LANL/KSWC/NOAA makes a Memorandum Of Understanding (MOU) on the collaboration between three parts. By this MOU, KWSC/RRA provides all the support for transitioning the research version of DREAM to operations. KASI is primarily responsible for providing all the interfaces between the current scientific output formats of the code and useful space weather products that can be used and accessed through the web. In the second phase, KASI will be responsible in performing the work needed to transform the Van Allen Probes beacon data into "DREAM ready" inputs. KASI will also provide the "operational" code framework and additional data preparation, model output, display and web page codes back to LANL and SWPC. KASI is already a NASA partnering ground station for the Van Allen Probes' space weather beacon data and can here show use and utility of these data for comparison between rtDREAM and observations by web. NOAA has offered to take on some of the data processing tasks specific to the GOES data.

  12. An assessment of ozone levels, UV radiation and their occupational health hazard estimation during photocopying operation

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Bhupendra Pratap, E-mail: bpsingh0783@gmail.com; Kumar, Amit; Singh, Deepak; Punia, Monika; Kumar, Krishan; Jain, Vinod Kumar

    2014-06-30

    Highlights: • First quantitative report of ozone level and UV radiation emission from photocopier. • Ozone production is directly proportional with intensity of photocopy operation. • Ozone level from ground floor is significantly higher than basement photocopier. • Ozone production and UV radiation studied has less correlation during photocopy. • Health hazard issue has been evaluated for effect of UV radiation in terms of SED. - Abstract: This study investigates the levels of ozone concentration along with an ultraviolet (UV) and visible spectral radiation at eight photocopy centers in an academic institute, Delhi. Sampling was done in two types of locations, i.e., basement photocopy centers (BPC) and ground floor photocopy centers (GPC) for 8 h. Measurements of levels of ozone, UV and visible radiation were done by ozone analyzer, UV radiometer and Field spectra instrument, respectively. Results show that the hourly mean concentration of ozone was observed to be in the range of 1.8–10.0 ppb and 5.3–45.8 ppb for BPC and GPC, respectively. In terms UV radiations, energy lies between 5.0 × 10{sup −3} and 7.0 × 10{sup −3} mW/cm{sup 2} for ultraviolet A (UVA), 1.0 × 10{sup −3} and 2.0 × 10{sup −3} mW/cm{sup 2} for ultraviolet B (UVB) and 6.0 × 10{sup −3} and 8.0 × 10{sup −3} mW/cm{sup 2} for ultraviolet C (UVC). Correlation between the UV radiations and ozone production observed was statistically insignificant. To know the health hazard occurred to the workers, the standard erythema dose (SED) value was calculated for emitting UV radiation. The SED was estimated to be in the range of 0.02–0.04 and 0.02–0.32 for direct and indirect methods which is less than the guideline prescribed by Commission Internationale del’ Eclairage (CIE). In nutshell, person involved in photocopy operation for their livelihood must be trained and should have knowledge for the long term gradual build up health problems due to ozone and UV production from

  13. Performance investigation of an automotive car radiator operated with nanofluid-based coolants (nanofluid as a coolant in a radiator)

    International Nuclear Information System (INIS)

    Leong, K.Y.; Saidur, R.; Kazi, S.N.; Mamun, A.H.

    2010-01-01

    Water and ethylene glycol as conventional coolants have been widely used in an automotive car radiator for many years. These heat transfer fluids offer low thermal conductivity. With the advancement of nanotechnology, the new generation of heat transfer fluids called, 'nanofluids' have been developed and researchers found that these fluids offer higher thermal conductivity compared to that of conventional coolants. This study focused on the application of ethylene glycol based copper nanofluids in an automotive cooling system. Relevant input data, nanofluid properties and empirical correlations were obtained from literatures to investigate the heat transfer enhancement of an automotive car radiator operated with nanofluid-based coolants. It was observed that, overall heat transfer coefficient and heat transfer rate in engine cooling system increased with the usage of nanofluids (with ethylene glycol the basefluid) compared to ethylene glycol (i.e. basefluid) alone. It is observed that, about 3.8% of heat transfer enhancement could be achieved with the addition of 2% copper particles in a basefluid at the Reynolds number of 6000 and 5000 for air and coolant respectively. In addition, the reduction of air frontal area was estimated.

  14. Experimental study of combustion noise radiation during transient turbocharged diesel engine operation

    International Nuclear Information System (INIS)

    Giakoumis, Evangelos G.; Dimaratos, Athanasios M.; Rakopoulos, Constantine D.

    2011-01-01

    Diesel engine noise radiation has drawn increased attention in recent years since it is associated with the passengers' and pedestrians' discomfort, a fact that has been acknowledged by the manufacturers and the legislation in many countries. In the current study, experimental tests were conducted on a truck, turbocharged diesel engine in order to investigate the mechanism of combustion noise emission under various transient schedules experienced during daily driving conditions, namely acceleration and load increase. To this aim, a fully instrumented test bed was set up in order to capture the development of key engine and turbocharger variables during the transient events. Analytical diagrams are provided to explain the behavior of combustion noise radiation in conjunction with cylinder pressure (spectrum), turbocharger and governor/fuel pump response. Turbocharger lag was found to be the main cause for the noise spikes during all test cases examined, with the engine injection timing calibration and the slow adjustment of cylinder wall temperature to the new fueling conditions playing a vital role. The analysis was extended with a quasi-steady approximation of transient combustion noise using steady-state maps, in order to better highlight the effect of dynamic engine operation on combustion noise emissions. -- Highlights: → Studying the effects of acceleration and load increase on the combustion noise radiation from a turbocharged diesel engine. → Turbocharger lag was the most notable contributor for the behavior of combustion noise radiation. → Turbocharged diesel engine behaves noisier at acceleration compared with the steady-state operation. → Fuel limiter, governing and engine injection timing calibration play a decisive role on the emission of combustion noise. → Transient noise radiation was smoothed the slower the acceleration and the smaller the demanded speed increase.

  15. A basic operational radiation protection programme for developing countries - P1.041

    International Nuclear Information System (INIS)

    Rozental, Jose de Julio; Ministry of Environment

    2001-01-01

    In many developing countries the necessary laws and regulatory framework are lacking. It is estimated that there are more than 50 countries having insufficient radiation protection and waste management infrastructures, which encompass laws and regulations that are the basis on which these infrastructures are developed. This is particularly the case of countries, which do not have a nuclear power programme, nuclear research reactors or a long experience of work with radiation sources. One action initiated by the IAEA was the introduction of an inter regional model project on radiation protection which purpose is to help those countries recipients of technical assistance, to improve marginal radiation protection programs. Considering the IAEA Basic Safety Standards this paper describes the basis for such essential operational radiation protection programme, that should be started after a complete tabletop debate to discuss exhaustively the topics and necessary basic actions toward the implementation of a National Regulatory Infrastructure on Radiation Safety, initially using the realistic situation in the country, that's mean: legislation, human and material resources already available. The main directives, based on the IAEA - Basic Safety Standards are: motivation toward Safety Culture to stimulate the Government to be engaged in this expectation; elaboration of the basic regulations and norms; practices in the Country, geographical distribution and category of hazard; basic Regulatory Authority requirement; resources available in the country (human and material) in terms of staff, persons related and facilities; integration of Authorities according to the Point of Optimum Contact; establishment of a plan for training internal and regional, and compliance monitoring; establishment of regulation for effective enforcement action, IAEA assistance. (author)

  16. Radiation exposure to operating room staff during prostate brachytherapy using iodine-125 seeds

    International Nuclear Information System (INIS)

    Gagna, G.; Amabile, J.C.; Laroche, P.; Gauron, C.

    2011-01-01

    The French defense radiation protection service (SPRA) and the French national institute for research and safety (INRS) conducted a joint study to assess the radiation exposure to operating room staff during prostate brachytherapy using iodine-125 seeds at the Val-de-Grace military hospital. The purpose of the study was the assessment of the effective doses, the equivalent doses to the extremities and lens received by a novice team, the different ambient dose equivalent rates measurements and the delineation of areas. After six brachy-therapies, all the recorded doses with whole-body InLight R OSL and nanoDot R dosimeters remained below the detection limit for the whole staff. The dose rate measured at the end of implantation by an AT1123 R survey meter is about 170 μSv/h at the perineum of the patient. The controlled area limit is estimated to be about 20 cm from the patient perineum. From these results, the authors propose recommendations for the categorization of workers, the delineation of areas and the dose monitoring procedures. This study demonstrates that real-time ultrasound-guided trans-perineal prostate brachytherapy delivers low dose to the operators because of the radioactive source characteristics and the instrumentation providing an effective radiation protection for the surgical team. (authors)

  17. Nuclear safety and radiation protection report of the Tricastin operational hot base nuclear facilities - 2013

    International Nuclear Information System (INIS)

    2014-01-01

    This safety report was established under the article 21 of the French law no. 2006-686 of June 13, 2006 relative to nuclear safety and information transparency. It presents, first, the Tricastin operational hot base facility (INB no. 157, Bollene, Vaucluse (FR)), a nuclear workshop for storage and maintenance and qualification operations on some EdF equipments. Then, the nuclear safety and radiation protection measures taken regarding the facility are reviewed: nuclear safety definition, radiation protection of intervening parties, safety and radiation protection improvement paths, crisis management, external and internal controls, technical situation of facilities, administrative procedures in progress. The incidents and accidents which occurred in 2013, if some, are reported as well as the effluents discharge in the environment. Finally, The radioactive materials and wastes generated by the facility is presented and sorted by type of waste, quantities and type of conditioning. The document concludes with a glossary and a list of recommendations from the Committees for health, safety and working conditions

  18. Radiation safety and operational health physics of hospital based medical cyclotrons

    International Nuclear Information System (INIS)

    Mukherjee, B.

    2002-01-01

    Full text: Compact, low energy, high current Medical Cyclotrons are now primarily used to produce large activities of short lived, neutron deficient, positron- emitting radioisotopes. These isotopes constitute the key ingredients of important PET (Positron Emission Tomography) radiopharmaceuticals used in diagnostic nuclear medicine. The PET-radioisotope producing Medical Cyclotrons are now increasingly installed in modern urban hospitals in many countries of the world. Modern Medical Cyclotrons run at a very high beam current (∼100-200 micro Amp) level and thereby produce intense fields of parasitic gamma rays and neutrons, causing the activation of cyclotron components, ambient air and radiation exposure to patients and members of the public. This report highlights the important operational aspects and the characteristics of the radiation fields produced by Medical Cyclotrons. The pathways of personnel radiation exposure are also analyzed. The above information constitutes the scientific basis of a sound operational health physics service, which is manifested in an effective dose reduction and an enhanced radiological safety of the Medical Cyclotron facility within the framework of ALARA

  19. Operational accidents and radiation exposure experience within the United States Atomic Energy Commission, 1943--1975

    International Nuclear Information System (INIS)

    1975-01-01

    The occupational injury and fatality experience during 32 years of the development of the atomic energy industry under the direction of the Atomic Energy Commission (AEC) and its predecessor, the Manhattan Engineering District, is reviewed. Data are included on the cause of all accidents, including fires and transportation accidents, and the cost of AEC property damage. Fatalities of AEC and contractor personnel from all causes during the 32-year period totaled 321, of which 184 occurred in construction; 121 in AEC operations such as production, research, and services; and 16 in Government functions. There were 19,225 lost-time injuries attributable to all accidental causes, or a 32-year frequency rate of 2.75 based on the number of injuries per million man-hours. There were six deaths attributable to nuclear causes, thee of which were due to blast and flying missiles and three caused by whole-body radiation exposure. Forty-one workers were involved in lost-time radiation accidents, of whom 26 showed clinical manifestations attributable to radiation, resulting in permanent partial-disability of three workers and the loss of a digit by four workers, while the others did not develop evidence of radiation injury

  20. The provision of Technical Co-operation: The model project for upgrading radiation protection infrastructure

    International Nuclear Information System (INIS)

    Barretto, P.M.C.

    2001-01-01

    The paper describes the IAEA's systematic effort to address the inadequate situation in many of its Member States with regard to radiation protection and safety. For this effort a special project was created and implemented in the past five years to create or strengthen existing radiation protection infrastructure in 52 countries where such infrastructure was non-existent or not appropriate for the type of practice involved. The implementation of this project focused on the development of qualified human resources, assistance for introduction of appropriate legislation and equipment for inspection and analysis. Workplans were tailored to the individual needs of each participating country and the elements of these workplans were grouped into five milestones -- regulatory framework, occupational exposure control, medical exposure control, public exposure control, and emergency preparedness and response capabilities. By the end of 2000 more than 70% of the participating countries had radiation protection laws promulgated and a regulatory authority established; 46% had regulations adopted and 42% had a system of notification, authorization and control of radiation sources operational. During the five years of implementation, 555 fellows received individual training, another 2278 participated in training courses, over 1000 expert missions were fielded and equipment worth about US $6 million was provided. The total cost was over US $17 million. (author)

  1. Radiation

    International Nuclear Information System (INIS)

    2013-01-01

    The chapter one presents the composition of matter and atomic theory; matter structure; transitions; origin of radiation; radioactivity; nuclear radiation; interactions in decay processes; radiation produced by the interaction of radiation with matter

  2. EMERALD-NORMAL, Routine Radiation Release and Dose for PWR Design Analysis and Operation Analysis

    International Nuclear Information System (INIS)

    Gillespie, S.G.; Brunot, W.K.

    1976-01-01

    1 - Description of problem or function: EMERALD-NORMAL is designed for the calculation of radiation releases and exposures resulting from normal operation of a large pressurized water reactor. The approach used is similar to an analog simulation of a real system. Each component or volume in the plant which contains a radioactive material is represented by a subroutine which keeps track of the production, transfer, decay, and absorption of radioactivity in that volume. During the course of the analysis, activity is transferred from subroutine to subroutine in the program as it would be transferred from place to place in the plant. Some of this activity is then released to the atmosphere and to the discharge canal. The rates of transfer, leakage, production, cleanup, decay, and release are read as input to the program. Subroutines are also included which calculate the off-site radiation exposures at various distances for individual isotopes and sums of isotopes. The program contains a library of physical data for the forty isotopes of most interest in licensing calculations, and other isotopes can be added or substituted. Because of the flexible nature of the simulation approach, the EMERALD-NORMAL program can be used for most calculations involving the production and release of radioactive material. These include design, operation, and licensing studies. 2 - Method of solution: Explicit solutions of first-order linear differential equations are included. In addition, a subroutine is provided which solves a set of simultaneous linear algebraic equations. 3 - Restrictions on the complexity of the problem: Many parameters and systems included in the program, particularly the radiation waste-treatment system, are unique to the PG and E Diablo Canyon PWR plant. Maxima of: 50 isotopes, 9 distances, 16 angular sectors, 1 operating period, 1 reactor power level

  3. TNT Maritime Interdiction Operation Experiments: Enabling Radiation Awareness and Geographically Distributed Collaboration for Network-Centric Maritime Interdiction Operations [Preprint

    National Research Council Canada - National Science Library

    Bordetsky, Alex; Dougan, Arden; Chiann, Foo Y; Kilberg, Andres

    2007-01-01

    ...) comprised of long-haul OFDM networks combined with self-forming wireless mesh links to radiation detection sensors, and real-time radiation awareness collaboration with geographically distributed partners...

  4. Operational Experience and Performance with the ATLAS Pixel detector with emphasis on radiation damage

    CERN Document Server

    Butti, Pierfrancesco; The ATLAS collaboration

    2017-01-01

    The tracking performance of the ATLAS detector relies critically on its 4-layer Pixel Detector, that has undergone significant hardware and software upgrades to meet the challenges imposed by the higher collision energy, pileup and luminosity that are being delivered by the Large Hadron Collider, with record breaking instantaneous luminosities of 1.3 x 10^34 cm-2 s-1 recently surpassed. The key status and performance metrics of the ATLAS Pixel Detector are summarised, and the operational experience and requirements to ensure optimum data quality and data taking efficiency are described, with special emphasis to radiation damage experience.

  5. Operational Experience and Performance with the ATLAS Pixel detector with emphasis on radiation damage

    CERN Document Server

    Garcia Pascual, Juan Antonio; The ATLAS collaboration

    2017-01-01

    The tracking performance of the ATLAS detector relies critically on its 4-layer Pixel Detector, that has undergone significant hardware and software upgrades to meet the challenges imposed by the higher collision energy, pileup and luminosity that are being delivered by the Large Hadron Collider, with record breaking instantaneous luminosities of 1.3 x 10$^{34}$ cm$^{-2}$ s$^{-1}$ recently surpassed. The key status and performance metrics of the ATLAS Pixel Detector are summarised, and the operational experience and requirements to ensure optimum data quality and data taking efficiency are described, with special emphasis to radiation damage experience.

  6. Stress and Fatigue in Operators Under Radiofrequency Electromagnetic Radiation and Shift Work

    Directory of Open Access Journals (Sweden)

    Vangelova K.

    2014-12-01

    Full Text Available The aim was to study the effect of radiofrequency electromagnetic radiation (EMR on stress indices, health complaints and fatigue of operators working fast-rotating extended shifts. Working conditions, job content, job control, social support, health complaints and fatigue were followed in 220 operators, 110 exposed to EMR and 110 control operators, matched by age and sex. The EMR was measured and time-weighted average (TWA was calculated. The excretion rates of stress hormones cortisol, adrenaline and noradrenaline were followed during the extended shifts in 36 operators, working at different levels of exposure and 24-hour exposure was calculated. The exposed group pointed more problems with the working conditions, including EMR, noise, currents and risk of accidents, more health complaints and higher level of fatigue. The most common health complaints were mental and physical exhaustion after work, pains in the chest, musculoskeletal complaints, headache, and apathy. High level EMR exposure (TWAmean = 3.10 μW/cm2, TWAmax = 137.00 μW/cm2 significantly increased the 24-hour excretion of cortisol and noradrenaline, whereas the increase of adrenaline excretion did not reach significance, as well as hormone excretion rates under low level exposure (TWAmean = 1.89 μW/cm2, TWAmax = 5.24 μW/cm2. In conclusion, higher number of health complaints, higher stress hormone excretion rates and fatigue were found in operators under EMR.

  7. Evaluation of radiation dose during sent-graft treatment using a hybrid operating room system

    International Nuclear Information System (INIS)

    Haga, Yoshihiro; Kaga, Yuji; Chida, Koichi

    2015-01-01

    In recent years, aortic aneurysm treatment with stent graft grafting in the X-ray fluoroscopy is increasing. This is an endovascular therapy, because it is a treatment which includes the risk of radiation damage, having to deal with radiation damage, to know in advance is important. In this study, in order to grasp the trend of exposure stent graft implantation in a hybrid operating room (OR) system, focusing on clinical data (entrance skin dose and fluoroscopy time), was to count the total. In TEVAR and EVAR, fluoroscopy time became 13.40 ± 7.27 minutes, 23.67 ± 11.76 minutes, ESD became 0.87 ± 0.41 mGy, 1.11 ± 0.57 mGy. (fluoroscopy time of EVAR was 2.0 times than TEVAR. DAP of EVAR was 1.2 times than TEVAR). When using the device, adapted lesions and usage are different. This means that care changes in exposure-related factors. In this study, exposure trends of the stent graft implantation was able to grasp. It can be a helpful way to reduce/optimize the radiation dose in a hybrid OR system. (author)

  8. [Evaluation of Radiation Dose during Stent-graft Treatment Using a Hybrid Operating Room System].

    Science.gov (United States)

    Haga, Yoshihiro; Chida, Kouichi; Kaga, Yuji; Saitou, Kazuhisa; Arai, Takeshi; Suzuki, Shinichi; Iwaya, Yoshimi; Kumasaka, Eriko; Kataoka, Nozomi; Satou, Naoto; Abe, Mitsuya

    2015-12-01

    In recent years, aortic aneurysm treatment with stent graft grafting in the X-ray fluoroscopy is increasing. This is an endovascular therapy, because it is a treatment which includes the risk of radiation damage, having to deal with radiation damage, to know in advance is important. In this study, in order to grasp the trend of exposure stent graft implantation in a hybrid operating room (OR) system, focusing on clinical data (entrance skin dose and fluoroscopy time), was to count the total. In TEVAR and EVAR, fluoroscopy time became 13.40 ± 7.27 minutes, 23.67 ± 11.76 minutes, ESD became 0.87 ± 0.41 mGy, 1.11 ± 0.57 mGy. (fluoroscopy time of EVAR was 2.0 times than TEVAR. DAP of EVAR was 1.2 times than TEVAR.) When using the device, adapted lesions and usage are different. This means that care changes in exposure-related factors. In this study, exposure trends of the stent graft implantation was able to grasp. It can be a helpful way to reduce/optimize the radiation dose in a hybrid OR system.

  9. [(111)In-DTPA]octreotide tumor uptake in GEPNET liver metastases after intra-arterial administration: an overview of preclinical and clinical observations and implications for tumor radiation dose after peptide radionuclide therapy.

    Science.gov (United States)

    Pool, Stefan E; Kam, Boen L R; Koning, Gerben A; Konijnenberg, Mark; Ten Hagen, Timo L M; Breeman, Woulter A P; Krenning, Eric P; de Jong, Marion; van Eijck, Casper H J

    2014-05-01

    With the aim to improve peptide receptor radionuclide therapy effects in patients with gastroenteropancreatic neuroendocrine tumor (GEPNET) liver metastases we explored the effect of intra-arterial (IA) administration of [(111)In-DTPA]octreotide ((111)In-DTPAOC) on tumor uptake in an animal model and in a patient study. Preclinical study: After administering (111)In-DTPAOC intra-venously (IV) or IA, biodistribution studies were performed in rats with a hepatic somatostatin receptor subtype 2 (sst2)-positive tumor. Clinical study: 3 patients with neuroendocrine liver metastases were injected twice with (111)In-DTPAOC. The first injection was given IV, and 2 weeks later, the second was injected IA (hepatic artery). Planar images of the abdomen were made up to 72 hours after injection. Blood samples were taken and urine was collected. Pharmacokinetic modeling was performed on the IV and IA data of the same patient. Based on this model, additional (177)Lu dosimetry calculations for IV and IA administrations were performed. The preclinical study showed a two-fold higher (111)In-DTPAOC tumor uptake after IA administration than after IV injection. Patient data showed a large variability in radioactivity increment in liver metastases after IA administration compared with IV administration. Renal radioactivity was not significantly lower after IA administration; (177)Lu dosimetry simulations in 1 patient using a maximum kidney radiation dose of 23 Gy showed IA administration resulted in a mean increase in tumor radiation dose of 2.9-fold. Preclinical and clinical data both indicate that IA administration of radiolabeled somatostatin analogs via the hepatic artery can significantly increase radionuclide uptake in GEPNET, sst2-positive, liver metastases up to 72 hours postinjection, although the effect of IA administration can differ between patients.

  10. Important radiation protection aspects of the operation of a commercial medical cyclotron

    International Nuclear Information System (INIS)

    Mukherjee, B.

    1997-01-01

    Since July 1991 the Radiopharmaceutical Division of the Australian Nuclear Science and Technology Organisation (ANSTO) operates a 30 MeV H'- ion Medical Cyclotron (Model; CYCLONE 30, Manufacturer: Ion Beam Applications, Louvain La Neuve, Belgium). During routine isotope production operations at the cyclotron a thick copper substrate plate electroplated with thin layer of selected enriched target material are bombarded with 30 MeV proton beam current up to 450 μA. The nuclear reaction of protons with the copper atoms result in the reduction of prompt evaporation neutrons with a peak energy of ∼ 1.8 MeV. These evaporation neutrons slow down via multiple collisions with the concrete shielding walls of the target cave, bounce back to the,interior space of the cave activating the cyclotron parts, beam tube components and other utilities installed in the irradiation cave. After the completion of 60 hour isotope production run, gamma dose equivalent rates of ∼10 5 μSvh -1 were measured at contact with the target irradiation stations and beam collimators. Evidently, these gamma rays emitted from the activated cyclotron components impose crucial radiation exposure hazard problems for the cyclotron maintenance technicians. Experiments had been carried out in order to identify the specific pathways of cyclotron component activation and to assess the probable personnel radiation exposure during handling of the activated cyclotron parts. The cool-down (radioactive decay) of the activated cyclotron components was estimated experimentally at different target bombardment conditions using the wall mounted gamma area monitors interfaced to the Health Physics Data Acquisition System. The gamma dose equivalent rates at contact with various locations of interest at the target irradiation station and at the typical work areas of the maintenance personnel were carefully recorded with a radiation (gamma) survey instrument during the three years operation period of the cyclotron. A

  11. From cities and towns to urban networks in Germany – intra regional competition versus regional co-operation and inter regional competitiveness

    Directory of Open Access Journals (Sweden)

    Bernhard Mueller

    2000-01-01

    Full Text Available For many decades of the 20th century particular cities and towns were understood as integral parts of national and international urban systems. For many years the theory on central places and hierarchy of central places, first developed by Christaller and amended by Loesch, had a decisive influence on spatial research and regional development policies with guiding principles for urbanisation and the development of settlement patterns. However it is becoming ever more evident, that the planned effects of concepts for harmonising intra- and inter-regional differences were not reached. Moreover, inter-regional competition between neighbouring municipalities, as well as modern life styles and residential choices have caused the emergence of new settlement structures with dispersed spatial patterns and string functional ties. It is also true, that urban networking isn’t an easy task and that it inherently carries numerous obstacles.

  12. Sweden's Co-operation with Eastern Europe in Radiation Safety 2011

    Energy Technology Data Exchange (ETDEWEB)

    Dassen, Lars van; Andersson, Sarmite; Bejarano, Gabriela; Chirman, Inessa; Delalic, Zlatan; Ekblad, Christer; Karlberg, Olof; Klasen, Haakan; Olsson, Kjell; Sandberg, Viviana; Stenberg, Tor; Turner, Roland; Wickman, Barbro

    2012-11-01

    In 2011, the Swedish Radiation Safety Authority implemented co-operation projects in Russia, Ukraine, Georgia, Lithuania and Moldova, based on instructions from the Swedish Government and agreements with the European Union and the Swedish International Development Co-operation Agency, SIDA. The projects aim at achieving a net contribution to radiation safety (including nuclear safety, nuclear security, waste management, nonproliferation as well as radiation protection and emergency preparedness) for the benefit of the host countries and the international community as well as Sweden. This report gives an overview of all the projects implemented in 2011. The project managers from SSM are the cornerstones of our successful work, but all the efforts and dedication by staff members of the facilities and authorities in the mentioned countries are indispensable for the long-term positive outcomes. This report is meant to serve as a detailed account regarding SSM's efforts as part of the Swedish international activities, on which Sweden will report to the Nuclear Security Summit in Seoul. The parties to the G-8 Global Partnership have in June 2011 extended the Global Partnership for ten more years, till 2022. Other international frameworks, such as the UNSC Resolution 1540, remain a vibrant instrument by which UN Member States can exchange information on security concerns and request assistance from each other. The projects that SSM implements in Moldova and Georgia have a reference to the aims and purposes of the UNSC Resolution 1540. Much work has been done in the fields of nuclear security and safety, but there are still lots of issues that need to be taken care of. As such, SSM will continue to do its part for nuclear safety and security at the international level, along the lines and priorities set by our Government.

  13. Sweden's Co-operation with Eastern Europe in Radiation Safety 2011

    International Nuclear Information System (INIS)

    Dassen, Lars van; Andersson, Sarmite; Bejarano, Gabriela; Chirman, Inessa; Delalic, Zlatan; Ekblad, Christer; Karlberg, Olof; Klasen, Haakan; Olsson, Kjell; Sandberg, Viviana; Stenberg, Tor; Turner, Roland; Wickman, Barbro

    2012-03-01

    In 2011, the Swedish Radiation Safety Authority implemented co-operation projects in Russia, Ukraine, Georgia, Lithuania and Moldova, based on instructions from the Swedish Government and agreements with the European Union and the Swedish International Development Co-operation Agency, SIDA. The projects aim at achieving a net contribution to radiation safety (including nuclear safety, nuclear security, waste management, nonproliferation as well as radiation protection and emergency preparedness) for the benefit of the host countries and the international community as well as Sweden. This report gives an overview of all the projects implemented in 2011. The project managers from SSM are the cornerstones of our successful work, but all the efforts and dedication by staff members of the facilities and authorities in the mentioned countries are indispensable for the long-term positive outcomes. This report is meant to serve as a detailed account regarding SSM's efforts as part of the Swedish international activities, on which Sweden will report to the Nuclear Security Summit in Seoul. The parties to the G-8 Global Partnership have in June 2011 extended the Global Partnership for ten more years, till 2022. Other international frameworks, such as the UNSC Resolution 1540, remain a vibrant instrument by which UN Member States can exchange information on security concerns and request assistance from each other. The projects that SSM implements in Moldova and Georgia have a reference to the aims and purposes of the UNSC Resolution 1540. Much work has been done in the fields of nuclear security and safety, but there are still lots of issues that need to be taken care of. As such, SSM will continue to do its part for nuclear safety and security at the international level, along the lines and priorities set by our Government

  14. Excited meson radiative transitions from lattice QCD using variationally optimized operators

    Energy Technology Data Exchange (ETDEWEB)

    Shultz, Christian J. [Old Dominion Univ., Norfolk, VA (United States); Dudek, Jozef J. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Old Dominion Univ., Norfolk, VA (United States); Edwards, Robert G. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)

    2015-06-02

    We explore the use of 'optimized' operators, designed to interpolate only a single meson eigenstate, in three-point correlation functions with a vector-current insertion. These operators are constructed as linear combinations in a large basis of meson interpolating fields using a variational analysis of matrices of two-point correlation functions. After performing such a determination at both zero and non-zero momentum, we compute three-point functions and are able to study radiative transition matrix elements featuring excited state mesons. The required two- and three-point correlation functions are efficiently computed using the distillation framework in which there is a factorization between quark propagation and operator construction, allowing for a large number of meson operators of definite momentum to be considered. We illustrate the method with a calculation using anisotopic lattices having three flavors of dynamical quark all tuned to the physical strange quark mass, considering form-factors and transitions of pseudoscalar and vector meson excitations. In conclusion, the dependence on photon virtuality for a number of form-factors and transitions is extracted and some discussion of excited-state phenomenology is presented.

  15. Radiation dose considerations by intra-individual Monte Carlo simulations in dual source spiral coronary computed tomography angiography with electrocardiogram-triggered tube current modulation and adaptive pitch

    Energy Technology Data Exchange (ETDEWEB)

    May, Matthias S.; Kuettner, Axel; Lell, Michael M.; Wuest, Wolfgang; Scharf, Michael; Uder, Michael [University of Erlangen, Department of Radiology, Erlangen (Germany); Deak, Paul; Kalender, Willi A. [University of Erlangen, Department of Medical Physics, Erlangen (Germany); Keller, Andrea K.; Haeberle, Lothar [University of Erlangen, Department of Medical Informatics, Biometry and Epidemiology, Erlangen (Germany); Achenbach, Stephan; Seltmann, Martin [University of Erlangen, Department of Cardiology, Erlangen (Germany)

    2012-03-15

    To evaluate radiation dose levels in patients undergoing spiral coronary computed tomography angiography (CTA) on a dual-source system in clinical routine. Coronary CTA was performed for 56 patients with electrocardiogram-triggered tube current modulation (TCM) and heart-rate (HR) dependent pitch adaptation. Individual Monte Carlo (MC) simulations were performed for dose assessment. Retrospective simulations with constant tube current (CTC) served as reference. Lung tissue was segmented and used for organ and effective dose (ED) calculation. Estimates for mean relative ED was 7.1 {+-} 2.1 mSv/100 mAs for TCM and 12.5 {+-} 5.3 mSv/100 mAs for CTC (P < 0.001). Relative dose reduction at low HR ({<=}60 bpm) was highest (49 {+-} 5%) compared to intermediate (60-70 bpm, 33 {+-} 12%) and high HR (>70 bpm, 29 {+-} 12%). However lowest ED is achieved at high HR (5.2 {+-} 1.5 mSv/100 mAs), compared with intermediate (6.7 {+-} 1.6 mSv/100 mAs) and low (8.3 {+-} 2.1 mSv/100 mAs) HR when automated pitch adaptation is applied. Radiation dose savings up to 52% are achievable by TCM at low and regular HR. However lowest ED is attained at high HR by pitch adaptation despite inferior radiation dose reduction by TCM. circle Monte Carlo simulations allow for individual radiation dose calculations. (orig.)

  16. Mapping radiation transfer through sea ice using a remotely operated vehicle (ROV

    Directory of Open Access Journals (Sweden)

    M. Nicolaus

    2013-05-01

    Full Text Available Transmission of sunlight into and through sea ice is of critical importance for sea-ice associated organisms and photosynthesis because light is their primary energy source. The amount of visible light transferred through sea ice contributes to the energy budget of the sea ice and the uppermost ocean. However, our current knowledge on the amount and distribution of light under sea ice is still restricted to a few local observations, and our understanding of light-driven processes and interdisciplinary interactions is still sparse. The main reasons are that the under-ice environment is difficult to access and that measurements require large logistical and instrumental efforts. Hence, it has not been possible to map light conditions under sea ice over larger areas and to quantify spatial variability on different scales. Here we present a detailed methodological description for operating spectral radiometers on a remotely operated vehicle (ROV under sea ice. Recent advances in ROV and radiation-sensor technology have allowed us to map under-ice spectral radiance and irradiance on floe scales within a few hours of station time. The ROV was operated directly from the sea ice, allowing for direct relations of optical properties to other sea-ice and surface features. The ROV was flown close to the sea ice in order to capture small-scale variability. Results from the presented data set and similar future studies will allow for better quantification of light conditions under sea ice. The presented experiences will support further developments in order to gather large data sets of under-ice radiation for different ice conditions and during different seasons.

  17. EMERALD, Radiation Release and Dose after PWR Accident for Design Analysis and Operation Analysis

    International Nuclear Information System (INIS)

    Brunot, W.K.; Fray, R.R.; Gillespie, S.G.

    1988-01-01

    1 - Description of problem or function: The EMERALD program is designed for the calculation of radiation releases and exposures resulting from abnormal operation of a large pressurized water reactor (PWR). The approach used in EMERALD is similar to an analog simulation of a real system. Each component or volume in the plant which contains a radioactive material is represented by a subroutine which keeps track of the production, transfer, decay and absorption of radioactivity in that volume. During the course of the analysis of an accident, activity is transferred from subroutine to subroutine in the program as it would be transferred from place to place in the plant. For example, in the calculation of the doses resulting from a loss-of-coolant accident the program first calculates the activity built up in the fuel before the accident, then releases some of this activity to the containment volume. Some of this activity is then released to the atmosphere. The rates of transfer, leakage, production, cleanup, decay, and release are read in as input to the program. Subroutines are also included which calculate the on-site and off-site radiation exposures at various distances for individual isotopes and sums of isotopes. The program contains a library of physical data for the twenty-five isotopes of most interest in licensing calculations, and other isotopes can be added or substituted. Because of the flexible nature of the simulation approach, the EMERALD program can be used for most calculations involving the production and release of radioactive materials during abnormal operation of a PWR. These include design, operational, and licensing studies. 2 - Method of solution - Explicit solutions of first-order linear differential equations are included. In addition, a subroutine is provided which solves a set of simultaneous linear algebraic equations. 3 - Restrictions on the complexity of the problem - Maxima of: 25 isotopes, 7 time periods, 15 volumes or components, 10

  18. Standard operational radiation protection instructions for process instrumentation and control engineering applying radiometric equipment containing sealed sources

    International Nuclear Information System (INIS)

    1989-01-01

    According to article 16(3) of the Ordinance on the Implementation of Atomic Safety and Radiation Protection of 11 October 1984, operational radiation protection instructions have to be worked out for each type of nuclear energy application. Based on the valid legal provisions of the GDR and on experience and knowledge gained in practice, the most important operational instructions and procedures for the operation of radiometric equipment containing sealed sources were compiled. The example should enable the management to make the instructions directly applicable and, if necessary, to modify or supplement them

  19. Impact of fuel cladding failure events on occupational radiation exposures at nuclear power plants. Case study: PWR during routine operations

    International Nuclear Information System (INIS)

    Moeller, M.P.; Martin, G.F.; Haggard, D.L.

    1986-01-01

    The purpose of this report is to present data in support of evaluating the impact of fuel cladding failure events on occupational radiation exposure. To determine quantitatively whether fuel cladding failure contributes significantly to occupational radiation exposure, radiation exposure measurements were taken at comparable locations in two mirror-image pressurized-water reactors (PWRs) and their common auxiliary building. One reactor, Unit B, was experiencing degraded fuel characterized as 0.125% fuel pin-hole leakers and was operating at approximately 55% of the reactor's licensed maximum core power, while the other reactor, Unit A, was operating under normal conditions with less than 0.01% fuel pin-hole leakers at 100% of the reactor's licensed maximum core power. Measurements consisted of gamma spectral analyses, radiation exposure rates and airborne radionuclide concentrations. In addition, data from primary coolant sample results for the previous 20 months on both reactor coolant systems were analyzed. The results of the measurements and coolant sample analyses suggest that a 3560-megawatt-thermal (1100 MWe) PWR operating at full power with 0.125% failed fuel can experience an increase of 540% in radiation exposure rates as compared to a PWR operating with normal fuel. In specific plant areas, the degraded fuel may elevate radiation exposure rates even more

  20. Radiation Test Results for a MEMS Microshutter Operating at 60 K

    Science.gov (United States)

    Rapchun, David A.; Buchner, Stephen; Moseley, Harvey; Meyer, Stephen E.; Ray, Knute; Tuttle, Jim; Quinn, Ed; Buchanan, Ernie; Bloom, Dave; Hait, Tom; hide

    2007-01-01

    The James Webb Space Telescope (JWST), the successor to the Hubble Space Telescope, is due to be launched in 2013 with the goal of searching the very distant Universe for stars that formed shortly after the Big Bang. Because this occurred so far back in time, the available light is strongly red-shifted, requiring the use of detectors sensitive to the infrared portion of the electromagnetic spectrum. HgCdTe infrared focal plane arrays, cooled to below 30 K to minimize noise, will be used to detect the faint signals. One of the instruments on JWST is the Near Infrared Spectrometer (NIRSPEC) designed to measure the infrared spectra of up to 100 separate galaxies simultaneously. A key component in NIRSPEC is a Micro-Electromechanical System (MEMS), a two-dimensional micro-shutter array (MSA) developed by NASA/GSFC. The MSA is inserted in front of the detector to allow only the light from the galaxies of interest to reach the detector and to block the light from all other sources. The MSA will have to operate at 30 K to minimize the amount of thermal radiation emitted by the optical components from reaching the detector array. It will also have to operate in the space radiation environment that is dominated by the MSA will be exposed to a large total ionizing dose of approximately 200 krad(Si). Following exposure to ionizing radiation, a variety of MEMS have exhibited performance degradation. MEMS contain moving parts that are either controlled or sensed by changes in electric fields. Radiation degradation can be expected for those devices where there is an electric field applied across an insulating layer that is part of the sensing or controlling structure. Ionizing radiation will liberate charge (electrons and holes) in the insulating layers, some of which may be trapped within the insulating layer. Trapped charge will partially cancel the externally applied electric field and lead to changes in the operation of the MEMS. This appears to be a general principle for

  1. Adjuvant therapy of Dukes' C colon cancer by intra-arterial P-32 colloid for internal radiation therapy of the liver

    Energy Technology Data Exchange (ETDEWEB)

    Grady, E.D.

    1984-09-01

    To prevent probable occult metastatic liver cancer from progressing to clinical disease, the author used internal radiation therapy as an effective adjuvant to surgical excision of primary Dukes' C colonic cancer. A calculated radiation dose of 5000 rads was delivered to the liver by injecting radioactive 32-P chromic phosphate colloid through the superior mesenteric and celiac arteries. When this was done, the colloid passed through the intestines and was mixed thoroughly with the blood and delivered to the liver by the portal vein. The Kupffer cells in the liver trapped the colloid, and a minimum amount passed through the liver and got into the general circulation. This kept the amount of colloid deposited in the bone marrow to a minimum. In a phase-I pilot study in which nine patients were treated, no serious side effects were noted. In eight patients, the liver has remained free of cancer for more than 1 year.

  2. Effect of preoperative chemotherapy and radiation therapy during and after radical operation for esophageal cancer

    Energy Technology Data Exchange (ETDEWEB)

    Nakamichi, Sonoko; Fujino, Yuji; Taenaka, Nobuyuki; Yoshiya, Ikuto; Murata, Atsuo [Osaka Univ., Suita (Japan). Hospital

    1997-10-01

    The effect of preoperative chemotherapy and radiation therapy (CR therapy) on peri- and postoperative circulatory and respiratory status was studied retrospectively. Forty-two patients of esophageal cancer who had radical operation were included in this study. Twelve patients had CR therapy before operation (group CR) and 30 patients without CR (group N). During the operation there was more bleeding in group CR than in group N, necessitating more intraoperative blood transfusion in group CR. Body weight of group CR increased more than that of group N from the 1st to the 4th postoperative day. AaDo{sub 2} also increased in group CR on the 1st postoperative day, which was thought to reflect an increase in water in the lungs. Diuretics required during the postoperative period did not show difference between both groups. Plasma IL-6 level was lower in group CR than in group N, although there was no statistical significance. No patients died in both groups. In conclusion, postoperative body weight and AaDo{sub 2} in group CR increased more than those in group N. (author)

  3. Technical Function and Operation of the High Radiation Level Examination Laboratory, Building 3525, Rev. 1

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    1961-01-31

    This report is concerned with the nature and. scope of the technical services to be rendered. and the general plan proposed for operation of Building 3525, High Radiation Level Examination Laboratory (HRLEL) . The role of postirradiation examination in implementing the over-all task of irradiation testing for various programs under way at the Oak Ridge National Laboratory (ORNL) and the importance of this effort to the United States reactor development program are stressed. The shielded-cell complex with provisions for remote decontamination, hot- equipment storage , and maintenance is described, as well as other supporting activities which are incorporated into the facility . The proposed technical functions include general observation, mensuration, nondestructive testing, burnup and induced-activity measurements, fission-gas sampling and analysis, corrosion evaluation and related measurements, disassembly and cutup, metallographic examination, mechanical-property determinations, and x -ray diffraction analyses . Equipment design and operational features to improve detection and measurement of selected properties in radioactive materials are described, also . The current status on design, procurement, construction, and preoperational testing of in-cell equipment in the mockup is presented along with a forecast of future needs. The mode of operation, manpower requirements, and management of the facility are discussed.

  4. Remote Operating Monitoring Of Spatial Stability Magnets On A Kurchatov Source Of Synchrotron Radiation

    CERN Document Server

    Barkovsky, E V; Martynenko, V V; Novikov, V A; Udin, L I

    2004-01-01

    During operation of the accelerator because of a nonuniform warm -up of the ring base and constructions of installation there are angular and linear displacements of bending and focusing magnets of a Big Accelerator Ring (BR) of a Kurchatov Source of Synchrotron Radiation. With the purpose of remote operating monitoring of a spatial position of elements BR was used anglemetrical control and measuring system with digital and analog registration in a real time mode. The results of the first stage of a monitoring BR have shown high informativity of the given instrumental - methodical means. The basic radiants of cyclical thermoelastic alternating strains are detected; the amplitudes of angular and linear displacements of magnets from different internal factors evaluated during operation of the accelerator. Is established, that the maximum radial angular and linear displacements of magnets are watched in 3,5-4 day after switching on of installation and achieve in max 30-35 seconds of an arc or 120-150 microns in ...

  5. Technical Function and Operation of the High Radiation Level Examination Laboratory, Building 3525

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    1961-01-31

    This report is concerned with the nature and scope of the technical services to be rendered and the general plan proposed for operation of Building 3525, High Radiation Level Examination Laboratory (HRLEL). The role of postirradiation examination in implementing the over- all task of irradiation testing for various programs under way at the Oak Ridge National Laboratory (ORNL) and the importance of this effort to the United Stat es reactor development program are stressed . The shielded-cell complex with provisions for remote decontamination, hot-equipment storage, and maintenance is described, as well as other supporting activities which are incorporated into the facility. The proposed technical functions include general observation, mensuration, nondestructive testing, burnup and induced-activity measurements, fission-gas sampling and analysis, corrosion evaluation and related measurements, disassembly and cutup, metallographic examination, mechanical-property determinations , and x -ray diffraction analyses. Equipment design and operational features to improve detection and measurement of selected properties in radioactive material s are described, also. The current status on design, procurement, construction, and preoperational testing of in- cell equipment in the mockup is presented along with a forecast of future needs. The mode of operation, manpower requirements, and management of the facility are discussed.

  6. Evaluation of the risk of liver damage from the use of 5-aminolevulinic acid for intra-operative identification and resection in patients with malignant gliomas

    DEFF Research Database (Denmark)

    Offersen, Cecilie Mørck; Skjoeth-Rasmussen, Jane

    2017-01-01

    BACKGROUND: The clinical efficacy of 5-aminolevulinic acid (5-ALA) for fluorescence-guided surgery of malignant gliomas is evident from several studies; however, as post-operative elevations of liver enzymes have been seen, there is a potential risk of liver damage upon administration. The aim...... (September 2012-September 2014) at the University Hospital of Copenhagen, Rigshospitalet, was conducted. All patients received a pre-operative dose of 20 mg/kg bodyweight 5-ALA. The pre- and post-operative enzyme levels of alanine aminotransferase, aspartate aminotransferase, gamma glutamyltransferase...... and amylase of both men and women, respectively, were evaluated. RESULTS: Ninety-nine adults met the inclusion criteria. Fifty patients had one or multiple temporary post-operative elevations of their liver enzymes. The mean post-operative values were not increased, except for a brief elevation of gamma...

  7. Operational safety and radiation protection considerations in designing an HLW repository in Germany

    International Nuclear Information System (INIS)

    Filbert, W.; Kreienmeyer, M.; Poehler, M.; Niehues, N.

    2008-01-01

    In Germany the reference concept for disposal of heat generating radioactive waste considers emplacing canisters with vitrified waste in deep vertical boreholes drilled from the drifts of a repository mine in salt at a depth of 870 m. Spent fuel is to be disposed of in self-shielding POLLUX casks in horizontal drifts. An optimized disposal concept anticipates emplacing unshielded canisters with vitrified HLW and canisters containing the fuel rods of 3 PWR or 9 BWR fuel assemblies in boreholes with a diameter of 60 cm and a depth of up to 300 m.. In all cases the void space between POLLUX cask and drifts and canisters and borehole wall will be backfilled with crushed salt. (1) Operational Safety: Based on a detailed description of all underground disposal operation steps, the possible impacts on the disposal operations were analysed and the need for further studies determined. The disposal operation steps comprise e.g. rail bound transport from the shaft to the emplacement drift and emplacement process itself. As possible impacts the following occurrences were considered: ventilation failure, power supply failure, rock mechanics impact including cross-section convergence, irregular floor uplift and rock fall, brine and natural gas intrusion, derailing of transport carts and finally internal fire. (2) Radiation Protection: According to the German Atomic Energy Act (AtG), the design, construction and operation of a nuclear site like a final repository has to be licensed by the responsible authority. The Radiological Protection Ordinance and further guidelines i.e. concerning the emission and immission of released radioactive nuclides or the risk analysis of possible failure, build the basis for the licensing procedures. To ensure adequate protection against undue radiation exposure the repository is divided into different radiological protection areas. Generally, the handling of shielded waste packages above und under ground (including all the pathway of transport and

  8. Reconfiguration of the multiwavelength operation of optical fiber ring lasers by the modifiable intra-cavity induced losses of an in-fiber tip probe modal Michelson interferometer

    Science.gov (United States)

    Salceda-Delgado, G.; Martinez-Rios, A.; Sierra-Hernandez, J. M.; Rodríguez-Carreón, V. C.; Toral-Acosta, D.; Selvas-Aguilar, R.; Álvarez-Tamayo, R. I.; Castillo-Guzman, A. A.; Rojas-Laguna, R.

    2018-03-01

    A straightforward and versatile method for switching from single to different multiwavelength laser emission in ring cavity fiber lasers is proposed and demonstrated experimentally. The method is based on using the changeable interference pattern from an optical fiber modal Michelson interferometer as a wavelength selective filter into the ring cavity laser. The interferometer is constructed using a bi-conical tapered fiber and a single-mode fiber segment, with these being spliced together to form an optical fiber tip probe. When the length of the single-mode fiber piece is modified, the phase difference between the interfering modes of the interferometer causes a change in the interferometer free spectral range. As a consequence, the laser intra-cavity losses lead to gain competition, which allows us to adjust the number of simultaneously generated laser lines. A multiwavelength reconfiguration of the laser from one up to a maximum of eight emission lines was obtained, with a maximum SNR of around 47 dBm.

  9. Effect of automated tube voltage selection, integrated circuit detector and advanced iterative reconstruction on radiation dose and image quality of 3rd generation dual-source aortic CT angiography: An intra-individual comparison.

    Science.gov (United States)

    Mangold, Stefanie; De Cecco, Carlo N; Wichmann, Julian L; Canstein, Christian; Varga-Szemes, Akos; Caruso, Damiano; Fuller, Stephen R; Bamberg, Fabian; Nikolaou, Konstantin; Schoepf, U Joseph

    2016-05-01

    To compare, on an intra-individual basis, the effect of automated tube voltage selection (ATVS), integrated circuit detector and advanced iterative reconstruction on radiation dose and image quality of aortic CTA studies using 2nd and 3rd generation dual-source CT (DSCT). We retrospectively evaluated 32 patients who had undergone CTA of the entire aorta with both 2nd generation DSCT at 120kV using filtered back projection (FBP) (protocol 1) and 3rd generation DSCT using ATVS, an integrated circuit detector and advanced iterative reconstruction (protocol 2). Contrast-to-noise ratio (CNR) was calculated. Image quality was subjectively evaluated using a five-point scale. Radiation dose parameters were recorded. All studies were considered of diagnostic image quality. CNR was significantly higher with protocol 2 (15.0±5.2 vs 11.0±4.2; pquality analysis revealed no significant differences for evaluation of attenuation (p=0.08501) but image noise was rated significantly lower with protocol 2 (p=0.0005). Mean tube voltage and effective dose were 94.7±14.1kV and 6.7±3.9mSv with protocol 2; 120±0kV and 11.5±5.2mSv with protocol 1 (pquality in comparison to 120kV imaging with FBP. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  10. Optimum engineering for low radiation exposure in BWRs and the operating experience

    International Nuclear Information System (INIS)

    Osumi, Katsumi; Tsuruoka, Ryozo; Uchida, Shunsuke; Izumiya, Masakiyo.

    1986-01-01

    Recently, accompanying the increase of the number of nuclear power stations in operation, it has been strongly desired to reduce radiation exposure dose when the regular inspections and maintenance works have been carried out. In Hitachi Ltd., the technology of designing low dose plants was developed, in which the radiation exposure dose in a BWR power station of 1100 MWe output class was aimed to be limited up to 200 man-rem/year, and it has been applied to No.2 plant in the Fukushima No.2 Nuclear Power Station, Tokyo Electric Power Co., Inc., which is an improved standardized base plant, and the plants thereafter. In the low dose plants, according to the results of evaluating the rate of contribution of iron and cobalt generating amount to dose using a dose rate forecasting code, as the countermeasures for reducing iron crud and Co-60 radioactivity, the oxygen injection into feed water system, dual type condensate purification system and the adoption of low cobalt materials and corrosion resistant steel were decided, taking the economy in consideration. In the first regular inspection of the above No.2 plant, the total exposure dose of workers was 89 man-rem. (Kako, I.)

  11. Gamma Radiation Effects on the Electrical Parameters of Some Operational Amplifiers

    International Nuclear Information System (INIS)

    Ashry, H.A.; Soliman, F.A.S.; Swidan, A.M.; El-Ghana, M.; Abdel Rahman, W.A.

    2008-01-01

    In this work, the effect of gamma-radiation on different types of operational amplifiers (HA17741 OK, HA17741 1D1, LM741 CN and μtA741 CN) was studied. It is shown that a serious effect occurs on the electrical characteristics of the op-amp's, and consequently the devices lose their main features. The input offset voltage, offset current, and bias current are shown to increase with increasing gamma dose. Also, the closed loop gain of the op-amp's is shown to decrease with increasing gamma dose, where its rate of decrease is a function of frequency. As a result, the slew rate, common mode rejection ratio and input impedance were shown to decrease with increasing gamma dose levels. On the other hand, the output impedance is inversely proportion to the gain; so, its value increases with increasing gamma exposure. Finally, it is clearly shown that the radiation dependence of the op-amp electrical parameters is a function of the fabrication technique of the op-amp's, where, the op-amps of the types HA17741 IDI and HA17741 OK are shown to be less sensitive to gamma rays than the op-amps of the types LM741 CN and μtA741 CN

  12. A Remote-operated System to Map Radiation Dose in the Fukushima Daiichi Primary Containment Vessel

    Science.gov (United States)

    Nancekievill, M.; Jones, A. R.; Joyce, M. J.; Lennox, B.; Watson, S.; Katakura, J.; Okumura, K.; Kamada, S.; Katoh, M.; Nishimura, K.

    2018-01-01

    This paper describes the development of a submersible system based on a remote-operated vehicle coupled with radiation detectors to map the interior of the reactors at the Fukushima Daiichi nuclear power station. It has the aim oflocating fuel debris. The AVEXIS submersible vehicle used in this study has been designed as a low-cost, potentially disposable, inspection platform that is the smallest of its class and is capable of being deployed through a 150 mm diameter access pipe. To map the gamma-ray environment, a cerium bromide scintillator detector with a small form factor has been incorporated into the AVEXIS to identify radioactive isotopes via gamma-ray spectroscopy. This provides the combined system with the potential to map gamma-ray spectra and particle locations throughout submerged, contaminated facilities, such as Units 1, 2 and 3 of the Fukushima Daiichi nuclear power plant. The hypothesis of this research is to determine the sensitivity of the combined system in a submerged environment that replicates the combination of gamma radiation and water submersion but at lower dose rates.

  13. Radiation field control at the latest BWR plants -- design principle, operational experience and future subjects

    Energy Technology Data Exchange (ETDEWEB)

    Uchida, Shunsuke [Energy Research Lab., Ibaraki (Japan); Ohsumi, Katsumi; Takashima, Yoshie [Hitachi Works, Ibaraki (Japan)

    1995-03-01

    Improvements of operational procedures to control water chemistry, e.g., nickel/iron control, as well as application of hardware improvements for reducing radioactive corrosion products resulted in an extremely low occupational exposure of less than 0.5 man.Sv/yr without any serious impact on the radwaste system, for BWR plants involved in the Japanese Improvement and Standardization Program. Recently, {sup 60}C radioactively in the reactor water has been increasing due to less crud fixation on the two smooth surfaces of new type high performance fuels and to the pH drop caused by chromium oxide anions released from stainless steel structures and pipings. This increase must be limited by changes in water chemistry, e.g., applications of modified nickel/iron ratio control and weak alkali control. Controlled water chemistry to optimize three points, the plant radiation level and integrities of fuel and structural materials, is the primary future subject for BWR water chemistry.

  14. Operational experiences in radiation protection in fast reactor fuel reprocessing facility

    International Nuclear Information System (INIS)

    Meenakshisundaram, V.; Rajagopal, V.; Santhanam, R.; Baskar, S.; Madhusoodanan, U.; Chandrasekaran, S.; Balasundar, S.; Suresh, K.; Ajoy, K.C.; Dhanasekaran, A.; Akila, R.; Indira, R.

    2008-01-01

    The Compact Reprocessing facility for Advanced fuels in Lead cells (CORAL), situated at Indira Gandhi Centre for Atomic Research (IGCAR), Kalpakkam is a pilot plant to reprocess the mixed carbide fuel, for the first time in the world. Reprocessing of fuel with varying burn-ups up to 155 G Wd/t, irradiated at Fast Breeder Test Reactor (FBTR), has been successfully carried out at CORAL. Providing radiological surveillance in a fuel reprocessing facility itself is a challenging task, considering the dynamic status of the sources and the proximity of the operator with the radioactive material and it is more so in a fast reactor fuel reprocessing facility due to handling of higher burn-up fuels associated with radiation fields and elevated levels of fissile material content from the point of view of criticality hazard. A very detailed radiation protection program is in place at CORAL. This includes, among others, monitoring the release of 85 Kr and other fission products and actinides, if any, through stack on a continuous basis to comply with the regulatory limits and management of disposal of different types of radioactive wastes. Providing radiological surveillance during the operations such as fuel transport, chopping and dissolution and extraction cycle was without any major difficulty, as these were carried out in well-shielded and high integrity lead cells. Enforcement of exposure control assumes more importance during the analysis of process samples and re-conversion operations due to the presence of fission product impurities and also since the operations were done in glove boxes and fume hoods. Although the radiation fields encountered in process area were marginally higher, due to the enforcement of strict administrative controls, the annual exposure to the radiation workers was well within the regulatory limit. As the facility is being used as test bed for validation of prototype equipment, periodic inspection and maintenance of components such as centrifuge

  15. Reporting nuclear power plant operation to the Finnish Centre for Radiation and Nuclear Safety

    International Nuclear Information System (INIS)

    1997-01-01

    The Finnish Centre for Radiation and Nuclear safety (STUK) is the authority in Finland responsible for controlling the safety of the use of nuclear energy. The control includes, among other things, inspection of documents, reports and other clarification submitted to the STUK, and also independent safety analyses and inspections at the plant site. The guide presents what reports and notifications of the operation of the nuclear facilities are required and how they shall be submitted to the STUK. The guide does not cover reports to be submitted on nuclear material safeguards addressed in the guide YVL 6.10. Guide YVL 6.11 presents reporting related to the physical protection of nuclear power plants. Monitoring and reporting of occupational exposure at nuclear power plants is presented in the guide YVL 7.10 and reporting on radiological control in the environment of nuclear power plants in the guide YVL 7.8

  16. Self-Sustained Operation of Radiation Detectors Based on Embedded Signal Processing

    International Nuclear Information System (INIS)

    Talnishnikh, Elena; Paganini, Lucia; Stegenga, Jan; Woertche, Heinrich; Limburgy, Han

    2013-06-01

    Radiation detectors featuring long term stability, self-sustained operation and low power consumption are crucial for long-term environmental monitoring (e.g. nuclear waste disposals and mining activities) and provide enhanced applications of nuclear fingerprinting e.g. in farming and geological surveying. INCAS3 is developing a compact modular system consisting of four functional modules, namely analogue conditioning and signal digitalization, dead-time-free real-time signal processing, embedded high level analysis of the processed signal, and wireless communication. The modules are organized such that they can be interchanged and modified independently. For the input module one can choose an ADC sampling frequency to be either 100 MHz with 14 bit precision or 1 GHz with reduced precision (10 bit). The main focus of the signal processing section, based on an FPGA, is on providing dead-time-free signal handling in real time. Other useful features such as base line correction, pulse shape analysis (energy, decay and arrival time) are being developed as (VHDL) library functions. Additional modules, e.g. anomaly detection in the incoming signal, pile-up correction if operated at high rates and advanced signal shape processing, can be included in the processing if required and can be applied to autonomously generate the information necessary to control the sensor parameters and stabilize energy spectra and sensitivity. At present we operate the system in conjunction with inorganic scintillators (NaI, CsI) read out by a photomultiplier in order to provide a system capable of long term quantification of nuclear contaminations in natural environments. The underlying technology is based on detecting natural or anthropogenic gamma radiation and generating corresponding energy spectra in real time. The generated spectra are analyzed either in a standard way by any suitable desktop software in a lab or, as it is described in this work, by the ENSA (Embedded Nuclear Spectra

  17. Significantly reduced radiation exposure to operators during kyphoplasty and vertebroplasty procedures: methods and techniques.

    Science.gov (United States)

    Ortiz, A O; Natarajan, V; Gregorius, D R; Pollack, S

    2006-05-01

    Vertebroplasty and kyphoplasty can be associated with significant radiation exposure to the operator. We compared the exposure levels to an operator performing vertebral fracture augmentation with vertebroplasty and kyphoplasty, to assess a cement injection and a monitoring technique designed to reduce this exposure. A neuroradiologist performed 189 consecutive vertebral augmentation procedures in 135 patients with osteoporotic compression fractures by using a bilateral approach with biplane pulse fluoroscopy at 7.5 pulses/second. Cement delivery was performed with intermittent fluoroscopy with kyphoplasty and vertebroplasty by using syringes or continuous fluoroscopic monitoring with a cement delivery system (CDS). Data collection included time and operator exposure parameters. A total of 87 kyphoplasty procedures, 82 vertebroplasty procedures with a CDS (VP-CDS), and 20 vertebroplasty procedures with syringes (VP-S) were safely performed. Mean fluoroscopy time for device positioning was 4.3 minutes for each procedure type. Mean fluoroscopy time (minutes) for cement delivery was significantly different for the 3 procedure types; 2.1 for kyphoplasty, 3.7 for VP-CDS, and 1.5 for VP-S (P exposure rates (microsieverts/minute) were 0.8 for kyphoplasty, 1.1 for VP-CDS, and 0.3 for VP-S during device-positioning and 1.7 for kyphoplasty, 2.9 for VP-CDS, and 0.2 for VP-S during cement injection (P technique and intermittent fluoroscopy with kyphoplasty and vertebroplasty with syringes results in a significantly lower operator exposure rate compared with vertebroplasty with a CDS.

  18. Results of environmental radiation monitoring and meteorology measurements (material prepared for obtaining the licence for RA reactor experimental operation)

    International Nuclear Information System (INIS)

    1980-10-01

    According to the demands for obtaining the licence for restarting the Ra reactor and the experimental operation this document includes the radiation monitoring measured data in the working space and environment of the RA reactor, i.e. Boris Kidric Institute. The meteorology measured data are included as well. All the measurements are performed according to the radiation protection program applied actually from the first reactor start-up at the end of 1959 [sr

  19. Radiation dose reduction with the adaptive statistical iterative reconstruction (ASIR) technique for chest CT in children: An intra-individual comparison

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Seung Hyun, E-mail: circle1128@yuhs.ac [Department of Radiology and Research Institute of Radiological Science, Severance Children' s Hospital, Yonsei University, College of Medicine, Seoul (Korea, Republic of); Kim, Myung-Joon, E-mail: mjkim@yuhs.ac [Department of Radiology and Research Institute of Radiological Science, Severance Children' s Hospital, Yonsei University, College of Medicine, Seoul (Korea, Republic of); Yoon, Choon-Sik, E-mail: yooncs58@yuhs.ac [Department of Radiology, Gangnam Severance Hospital, Yonsei University, College of Medicine, Seoul (Korea, Republic of); Lee, Mi-Jung, E-mail: mjl1213@yuhs.ac [Department of Radiology and Research Institute of Radiological Science, Severance Children' s Hospital, Yonsei University, College of Medicine, Seoul (Korea, Republic of)

    2012-09-15

    Objective: To retrospectively compare radiation dose and image quality of pediatric chest CT using a routine dose protocol reconstructed with filtered back projection (FBP) (the Routine study) and a low-dose protocol with 50% adaptive statistical iterative reconstruction (ASIR) (the ASIR study). Materials and methods: We retrospectively reviewed chest CT performed in pediatric patients who underwent both the Routine study and the ASIR study on different days between January 2010 and August 2011. Volume CT dose indices (CTDIvol), dose length products (DLP), and effective doses were obtained to estimate radiation dose. The image quality was evaluated objectively as noise measured in the descending aorta and paraspinal muscle, and subjectively by three radiologists for noise, sharpness, artifacts, and diagnostic acceptability using a four-point scale. The paired Student's t-test and the Wilcoxon signed-rank test were used for statistical analysis. Results: Twenty-six patients (M:F = 13:13, mean age 11.7) were enrolled. The ASIR studies showed 60.3%, 56.2%, and 55.2% reductions in CTDIvol (from 18.73 to 7.43 mGy, P < 0.001), DLP (from 307.42 to 134.51 mGy × cm, P < 0.001), and effective dose (from 4.12 to 1.84 mSv, P < 0.001), respectively, compared with the Routine studies. The objective noise was higher in the paraspinal muscle of the ASIR studies (20.81 vs. 16.67, P = 0.004), but was not different in the aorta (18.23 vs. 18.72, P = 0.726). The subjective image quality demonstrated no difference between the two studies. Conclusion: A low-dose protocol with 50% ASIR allows radiation dose reduction in pediatric chest CT by more than 55% while maintaining image quality.

  20. [Evaluation of the efficacy of sentinel node detection in breast cancer: chronological course and influence of the incorporation of an intra-operative portable gamma camera].

    Science.gov (United States)

    Goñi Gironés, E; Vicente García, F; Serra Arbeloa, P; Estébanez Estébanez, C; Calvo Benito, A; Rodrigo Rincón, I; Camarero Salazar, A; Martínez Lozano, M E

    2013-01-01

    To define the sentinel node identification rate in breast cancer, the chronological evolution of this parameter and the influence of the introduction of a portable gamma camera. A retrospective study was conducted using a prospective database of 754 patients who had undergone a sentinel lymph node biopsy between January 2003 and December 2011. The technique was mixed in the starting period and subsequently was performed with radiotracer intra-peritumorally administered the day before of the surgery. Until October 2009, excision of the sentinel node was guided by a probe. After that date, a portable gamma camera was introduced for intrasurgical detection. The SN was biopsied in 725 out of the 754 patients studied. The resulting technique global effectiveness was 96.2%. In accordance with the year of the surgical intervention, the identification percentage was 93.5% in 2003, 88.7% in 2004, 94.3% in 2005, 95.7% in 2006, 93.3% in 2007, 98.8% in 2008, 97.1% in 2009 and 99.1% in 2010 and 2011. There was a significant difference in the proportion of identification before and after the incorporation of the portable gamma camera of 4.6% (95% CI of the difference 2-7.2%, P = 0.0037). The percentage of global identification exceeds the recommended level following the current guidelines. Chronologically, the improvement for this parameter during the study period has been observed. These data suggest that the incorporation of a portable gamma camera had an important role. Copyright © 2013 Elsevier España, S.L. and SEMNIM. All rights reserved.

  1. Breast conserving operation and radiation therapy in early breast cancer: interim analysis

    International Nuclear Information System (INIS)

    Kim, Jin Hee; Kim, Ok Bae; Kim, You Sah

    2001-01-01

    To evaluate interim results in terms of failure, cosmetic results and survival after breast conserving operation and radiation therapy in early breast cancer. From January 1992 through December 1997, seventy two patients with early stage 0, I and II breast cancer were treated with conservative surgery plus radiotherapy at Keimyung University Dongsan Medical Center. Age distribution was 25 to 77 years old with median age of 43. Ac cording to TNM stage, five patients had stage 0, thirty three were stage I, twenty five were lIa, and nine were llb. Most patients underwent excision of all gross tumor and ipsilateral axillary dissection. Breast was irradiated through medial and lateral tangential fields of 6 MV photons to 50.4 Gy in 28 fractions over 5.5 weeks. We delivered a boost irradiation dose of 10 to 16 Gy in 1 to 2 weeks to excision site. Adjuvant chemotherapy was administered in forty one patients with CMF (cyclophosphamide, methotrexate, 5fluorouracil) regimens of 6 cycles concurrently or before radiation. Cosmetic results were assessed by questionnaire to patients grading of excellent, good, fair, poor. Follow-up periods were 22 to 91 months with median 40 months. Five year disease free survival rate (5YDFS) was 95.8%. According to stage, 5YDFS was 100%, 96.9%, 96% and 88.9% in stage 0, I, lIa and llb, respectively. Two patients had distant metastasis and one had local and distant failure. One patient with distant failure had bone and liver metastasis at 14 months after treatment and the other had lung and both supraclavicular metastasis at 21 months after treatment. Patient with local and distant failure had local recurrence on other quadrant in same breast and then salvaged with total mastectomy and chemotherapy but she died due to brain metastasis at 55 months. Complications were radiation pneumonitis in five patients (four patients of asymptomatic, one patient of symptomatic) and hand or arm edema(4 patients). Fifty nine patients answered our cosmetic

  2. Operational Radiation Protection in High-Energy Physics Accelerators: Implementation of ALARA in Design and Operation of Accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Fasso, A.; Rokni, S.; /SLAC

    2011-06-30

    It used to happen often, to us accelerator radiation protection staff, to be asked by a new radiation worker: ?How much dose am I still allowed?? And we smiled looking at the shocked reaction to our answer: ?You are not allowed any dose?. Nowadays, also thanks to improved training programs, this kind of question has become less frequent, but it is still not always easy to convince workers that staying below the exposure limits is not sufficient. After all, radiation is still the only harmful agent for which this is true: for all other risks in everyday life, from road speed limits to concentration of hazardous chemicals in air and water, compliance to regulations is ensured by keeping below a certain value. It appears that a tendency is starting to develop to extend the radiation approach to other pollutants (1), but it will take some time before the new attitude makes it way into national legislations.

  3. Operational Radiation Protection in High-Energy Physics Accelerators: Implementation of ALARA in Design and Operation of Accelerators

    International Nuclear Information System (INIS)

    Fasso, Alberto

    2011-01-01

    It used to happen often, to us accelerator radiation protection staff, to be asked by a new radiation worker: ?How much dose am I still allowed?? And we smiled looking at the shocked reaction to our answer: ?You are not allowed any dose?. Nowadays, also thanks to improved training programs, this kind of question has become less frequent, but it is still not always easy to convince workers that staying below the exposure limits is not sufficient. After all, radiation is still the only harmful agent for which this is true: for all other risks in everyday life, from road speed limits to concentration of hazardous chemicals in air and water, compliance to regulations is ensured by keeping below a certain value. It appears that a tendency is starting to develop to extend the radiation approach to other pollutants (1), but it will take some time before the new attitude makes it way into national legislations.

  4. Post-operative radiation therapy for advanced-stage oropharyngeal cancer.

    Science.gov (United States)

    Hansen, Eric; Panwala, Kathryn; Holland, John

    2002-11-01

    Between 1985 and 1999, 43 patients with locally-advanced, resectable oropharyngeal cancer were treated with combined surgery and post-operative radiation therapy (RT) at Oregon Health and Science University. Five patients (12 per cent) had Stage III disease and 38 patients (88 per cent) had Stage IV disease. All patients had gross total resections of the primary tumour. Thirty-seven patients had neck dissections for regional disease. RT consisted of a mean tumour-bed dose of 63.0 Gy delivered in 1.8-2.0 Gy fractions over a mean of 49 days. At three- and five-years, the actuarial local control was 96 per cent and the actuarial local/regional control was 80 per cent. The three- and five-year actuarial rates of distant metastases were 41 per cent and 46 per cent, respectively. The actuarial overall survival at three- and five-years was 41 per cent and 34 per cent, respectively. The actuarial rates of progression-free survival were 49 per cent at three-years and 45 per cent at five years. Combined surgery and post-operative RT for advanced-stage oropharyngeal cancer results in excellent local/regional control. This particular group of patients experienced a high-rate of developing distant metastases.

  5. An interesting case of bilateral bifid insertion of superior rectus muscle as an intra-operative finding in a patient with oculocutaneous albinism.

    Science.gov (United States)

    Verma, Rashmi; Hertle, Richard W

    2014-08-01

    We report a case of bilateral bifid insertion of superior rectus muscles, in a patient with oculocutaneous albinism as an incidental intraoperative finding during eye muscle surgery. The muscle was successfully operated on and the patient did well postoperatively. To our knowledge, this is the first report of this anomaly.

  6. A comparative study to validate the use of ultrasonography and computed tomography in patients with post-operative intra-abdominal sepsis

    NARCIS (Netherlands)

    Go, H. L. S.; Baarslag, H. J.; Vermeulen, H.; Laméris, J. S.; Legemate, D. A.

    2005-01-01

    Purpose: To validate abdominal Ultrasonography and helical computed tomography in detecting causes for sepsis in patients after abdominal surgery and to determine improved criteria for its use. Materials and methods: Eighty-five consecutive surgical patients primarily operated for non-infectious

  7. Laparoscopic sleeve gastrectomy without over-sewing the staple line: A case series demonstrating efficacy and minimization of both intra- and post-operative complications

    Directory of Open Access Journals (Sweden)

    Dr. S. Moradian, DO

    2017-01-01

    Conclusion: Our technique, to our knowledge, is the first to describe laparoscopic sleeve gastrectomy without over-sewing the staple line, no post-operative anticoagulation, no UGI series on POD#1, and discharge home on POD#1 with no major complications.

  8. Systemic review: Radiation therapy alone in medical non-operable endometrial carcinoma.

    Science.gov (United States)

    van der Steen-Banasik, E; Christiaens, M; Shash, E; Coens, C; Casado, A; Herrera, F G; Ottevanger, P B

    2016-09-01

    Radiotherapy is a good option for inoperable and frail patients diagnosed with endometrial cancer. Because of the lack of large multicentre trials, a systematic review was performed in an attempt to get an overview on the feasibility and efficacy of this specific approach. We performed a bibliographic search for articles in English or French which were published in PubMed from the start of this database in January 1969 to identify publications on radiation therapy (RT) as single treatment for localised non-operable carcinoma of the endometrium. The review was completed following the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. Twenty-five reports containing 2694 patients treated with RT as single treatment were identified that fulfilled the selection criteria. Disease-specific survival (DSS) at 5 years was reported for a cohort of 1322 (49.1%) patients. The combined DSS for this group of patients was 78.5% (range: 68.4-92%; 95% confidence interval: 74.5-82.5). External beam radiation therapy (EBRT) combined with brachytherapy (BT) was used in 1278 patients (47.4%), BT alone in 1383 patients (51.3%), and EBRT alone in 33 patients (1.2%). The average occurrence of grade III or worse late toxicity was 3.7% for EBRT + BT, 2.8% for BT alone, and 1.2% for EBRT alone. RT is in terms of disease control and toxicity, an acceptable option for non-surgical candidate patients. Prospective multicentre randomised or observational trials are needed to validate these results. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Evaluation of Knowledge, Attitude and Practice of Personnel in Operating Room, ERCP, and ESWL Towards Radiation Hazards and Protection

    Directory of Open Access Journals (Sweden)

    Shima Moshfegh

    2017-07-01

    Full Text Available Background Recently, X-rays radiation hazards rise with the exposure of patients and personnel. Exposure of people to radiation in the operating rooms is an important problem to study the safety of personnel and patients. To date, few studies are accomplished to evaluate knowledge, attitude, and practice (KAP among personnel in hospitals. The current study aimed at evaluating KAP level of radiation hazards and protection amongst personnel in the operating room. Methods A questionnaire-based, cross sectional study was conducted in 11 provinces of Iran from 2014 to 2015. Respondents in the current study were 332 personnel of operating room, endoscopic retrograde cholangiopancreatography, and extracorporeal shock-wave lithotripsy. Demographic characteristics, as well as knowledge, attitude, and practice levels of operating room personnel were collected. The selected hospitals were 3 types (educational, non-educational, and private clinics located in 5 different regions of Iran (Tehran, Center, East, North, and West. Data were analyzed using SPSS version 16.0 and statistical analyses were accomplished with the one-way ANOVA. Results The current study results showed no statistically significant difference in the KAP level of operating room personnel towards radiation protection for both genders (P = 0.1, time since graduation (P = 0.4, and work experience (P = 0.1. According to the analyses, the highest level of KAP concerning radiation protection was observed in the personnel of private clinics (mean score = 53.60 and the lowest value was observed in non-educational hospitals (mean score = 45.61. Besides, the KAP level was significantly higher in the Northern region (P < 0.0001 and the lowest was observed in the hospital personnel of the Central region (mean score = 34.27. Conclusions The current study findings showed that the level of KAP regarding radiation protection among operating room personnel was inadequate and it is necessary to pay

  10. A novel approach for evaluating acceptable intra-operative correction of lower limb alignment in femoral and tibial malunion using the deviation angle of the normal contralateral knee.

    Science.gov (United States)

    Wu, Chi-Chuan

    2014-03-01

    A simple and appropriate approach for evaluating an acceptable alignment of bone around the knee during operation has not yet been reported. Thirty-five men and 35 women presenting with nonunion or malunion of the unilateral femoral shaft were included in the first study. Using the standing scanograph, the contralateral normal lower extremity was measured to determine the normal deviation angle (DA) of the medial malleolus when the medial aspect of the knee was placed in the midline of the body. In the second study, the normal DA from individual patients was used as a reference to evaluate knee alignment during operation in 40 other patients presenting with distal femoral or proximal tibial nonunion or malunion. The clinical and knee functional outcomes of these 40 patients were investigated. The average normal DA was 4.2° in men and 6.0° in women (palignment was maintained in all 30 patients with fracture union. Satisfactory function of the knee was achieved in 28 patients (82%, palignment of bone around the knee during operation. Level IV, Case series. Copyright © 2012 Elsevier B.V. All rights reserved.

  11. Mean frequency and relative fluorescence intensity measurement of γ-H2AX foci dose response in PBL exposed to γ-irradiation: An inter- and intra-laboratory comparison and its relevance for radiation triage.

    Science.gov (United States)

    Venkateswarlu, Raavi; Tamizh, Selvan G; Bhavani, Manivannan; Kumar, Arun; Alok, Amit; Karthik, Kanagaraj; Kalra, Namita; Vijayalakshmi, J; Paul, Solomon F D; Chaudhury, N K; Venkatachalam, Perumal

    2015-12-01

    Measurement of γ-H2AX protein changes in the peripheral blood lymphocytes (PBL) of individuals exposed to ionizing radiation is a simple, sensitive, and rapid assay for radiation triage and early marker of dose estimation. The qualitative and quantitative measurements of the protein changes were examined using flow cytometry and microscopy. Whole blood and isolated lymphocytes were exposed in vitro between 0.1 and 5 Gy doses of (60) Co γ-radiation at a dose rate of 1 Gy/min. Radiation induced γ-H2AX foci frequency (n = 3) and relative fluorescence intensity (n = 7) in PBL was measured at 0.5 and 2 hrs postexposure. The observed dose response for γ-H2AX foci frequency at both time points, for whole blood and isolated lymphocytes did not show any significant (P > 0.05) differences. However, when compared with γ-H2AX foci frequency scored manually (microscopy), the semiautomated analysis (captured images) showed a better correlation (r(2) = 0.918) than that obtained with automated (Metafer) scoring (r(2) = 0.690). It is noteworthy to mention that, the γ-H2AX foci frequency quantified using microscopy showed a dose dependent increase up to 2 Gy and the relative fluorescence intensity (RFI) measured with flow cytometry revealed an increase up to 5 Gy in the PBL exposed in vitro. Moreover, a better correlation was observed between the γ-H2AX foci frequency obtained by manual scoring and RFI (r(2) = 0.910). Kinetic studies showed that the γ-H2AX foci remain more or less unchanged up to 4 hrs and reduces gradually over 48 hrs of postexposure at 37°C. Further, inter and intra-laboratory comparisons showed consistency in the scoring of γ-H2AX foci frequency by manual and semiautomated scoring. The overall results suggest that measurement of γ-H2AX (microscopy and flow cytometry) should be employed within 4 to 6 hrs for a reliable dosimetry either by sharing the work load between the laboratories or investing more manpower; however, triage can be possible even up

  12. Risks of the ionizing radiations for the anesthesia personnel in operating room in Hospital Dr. Rafael Angel Calderon Guardia

    International Nuclear Information System (INIS)

    Moro Alujas, Yassell N.

    2005-01-01

    The extent of the problem on the radiological exposure of anesthesiologists in the operating rooms was identified in the Hospital Rafael Angel Calderon Guardia, San Jose, Costa Rica. It was necessary to establish the risks in the professional disciplines more exposed to ionizing radiations, including Anesthesiology. Provides information on the radiations received by the anesthesia personnel as a risk factor of labor during professional practice. Within the findings were met dose ionizing radiation received by the participating subjects. It was determined that the monthly doses do not reach the limits of permissible dose average. Besides, no relationship was found between the number of procedures that were used ionizing radiations and the values of dosimetric measurements personal; but, if the type of procedure. In this way was showed that in some radiointerventional procedures there is a higher risk of irradiation [es

  13. Microscopical examination: the impact of different ionising radiation doses over protective clothing used in the operating theatre

    International Nuclear Information System (INIS)

    Abreu, M.J.; Cabec Silva, M.E.; Schacher, L.; Adolphe, D.

    2004-01-01

    The goals to be pursued by this paper are to highlight the effect of different ionising radiation methods, considered low temperature sterilisation, over protective clothing (surgical gowns) used in the operating theatre through microscopical examination. In order to investigate the influence of the radiation on the properties of nonwoven-based surgical gowns, two types of radiation (gamma and electron beam radiation) were considered in this study. The scanning electron microscope (SEM) is widely used in studies of polymers, although for this kind of nonwoven based structures, that goes through sterilisation treatments it isn't commonly used. So, this paper also intends to relate the results of the evaluation of comfort and barrier properties after irradiated at several doses in a range from 0 to 160 kGy. (orig.)

  14. Cross-Cultural Issues of Intra- and Inter-Organisational Cooperation in Space Operations: A Survey Study with Ground Personnel of the European Space Agency

    Science.gov (United States)

    Mjeldheim Sandal, Gro; Mjeldheim Sandal, Gro; Manzey, Dietrich

    Today's space operations often involve close co-working of people with different ethnical, professional and organizational backgrounds. The aim of the study was to examine the implications of cultural diversity for efficient collaboration within the European Space Agency (ESA), and between ESA employees and representatives from other agencies. Methods: A web-based survey was answered by 905 employees at the European Astronaut Centre and at the European Space Technology Centre. An adapted version of the Flight Management Attitude Questionnaire by Helmreich and Merrit was used. Personnel were also asked about interpersonal and operational issues that interfered with efficient co-working within ESA and in relation to other space agencies. Results: Collaboration within ESA: A descriptive analysis was conducted of the rank orders of challenges perceived by members of different nationalities (the Netherlands (N=68), German (N=138), Italian (N=135), French (N=124), British (N=84) and Scandinavian (27).Rank orders show a surprisingly uniformity across nationalities. Most respondents perceived differences in the preferred leadership style as the main challenge for co-working in multi-national groups followed by differences in dealing with conflicts and misunderstandings. In contrast communication problems due different languages and differences in non-verbal behaviour, as well as differences in gender stereotypes were among the lowest rated issues. However, Scandinavian respondents showed a different pattern from other nationalities. Collaboration between agencies: The most significant issues reported to interfere with the efficiency of inter-agency collaboration varied. Most difficulties were reported in relation to clarity of communication, insufficient sharing of task related information, understanding the process of decision making in partner organization, and authoritarian leadership style in the partner organization Conclusion: Cultural differences in leadership and

  15. Budget impact model of Mydrane®, a new intracameral injectable used for intra-operative mydriasis, from a UK hospital perspective.

    Science.gov (United States)

    Davey, Keith; Chang, Bernard; Purslow, Christine; Clay, Emilie; Vataire, Anne-Lise

    2018-04-19

    During cataract surgery, maintaining an adequate degree of mydriasis throughout the entire operation is critical to allow for visualisation of the capsulorhexis and the crystalline lens. Good anaesthesia is also essential for safe intraocular surgery. Mydrane® is a new injectable intracameral solution containing two mydriatics (tropicamide 0.02% and phenylephrine 0.31%) and one anaesthetic (lidocaine 1%) that was developed as an alternative to the conventional topical pre-operative mydriatics used in cataract surgery. This study aimed to estimate the budget impact across a one year time frame using Mydrane® instead of topical dilating eye drops, for a UK hospital performing 3,000 cataract operations a year. A budget impact model (BIM) was developed to compare the economic outcomes associated with the use of Mydrane® versus topical drops (tropicamide 0.5% and phenylephrine 10%) in patients undergoing cataract surgery in a UK hospital. The outcomes of interest included costs and resource use (e.g. clinician time, mydriasis failures, operating room time, number of patients per vial of therapy etc.) associated with management of mydriasis in patients undergoing cataract surgery. All model inputs considered the UK hospital perspective without social or geographical variables. Deterministic sensitivity analyses were also performed to assess the model uncertainty. Introduction of Mydrane® is associated with a cost saving of £6,251 over 3,000 cataract surgeries in one year. The acquisition costs of the Mydrane® (£18,000 by year vs. £3,330 for eye drops) were balanced by substantial reductions in mainly nurses' costs and time, plus a smaller contribution from savings in surgeons' costs (£20,511) and lower costs associated with auxiliary dilation (£410 due to avoidance of additional dilation methods). Results of the sensitivity analyses confirmed the robustness of the model to the variation of inputs. Except for the duration of one session of eye drop instillation

  16. Influence of accompanying immunocorrecting therapy on the quality of life of breast cancer patients at post-operative radiation therapy

    International Nuclear Information System (INIS)

    Prokhach, N.E.

    2013-01-01

    To investigate the influence of accompanying immunotherapy on the parameters of the quality of life of the patients with breast cancer with various profiles of cytokines at post-operative radiation therapy. The study was performed on 30 breast cancer patients at stages of combination therapy

  17. Estimated cumulative radiation dose received by diagnostic imaging during staging and treatment of operable Ewing sarcoma 2005-2012

    Energy Technology Data Exchange (ETDEWEB)

    Johnsen, Boel [Haukeland University Hospital, Centre for Nuclear Medicine and PET, Department of Radiology, P.O. Box 1400, Bergen (Norway); Fasmer, Kristine Eldevik [Haukeland University Hospital, Department of Oncology, Medical Physics Section, Bergen (Norway); Boye, Kjetil [Norwegian Radium Hospital, Oslo University Hospital, Department of Oncology, Oslo (Norway); Rosendahl, Karen; Aukland, Stein Magnus [Haukeland University Hospital, Department of Radiology, Paediatric Section, Bergen (Norway); University of Bergen, Department of Clinical Medicine, Bergen (Norway); Trovik, Clement [University of Bergen, Department of Clinical Medicine, Bergen (Norway); Haukeland University Hospital, Department of Surgery, Orthopaedic Section, Bergen (Norway); Biermann, Martin [Haukeland University Hospital, Centre for Nuclear Medicine and PET, Department of Radiology, P.O. Box 1400, Bergen (Norway); University of Bergen, Department of Clinical Medicine, Bergen (Norway)

    2017-01-15

    Patients with Ewing sarcoma are subject to various diagnostic procedures that incur exposure to ionising radiation. To estimate the radiation doses received from all radiologic and nuclear imaging episodes during diagnosis and treatment, and to determine whether {sup 18}F-fluorodeoxyglucose positron emission tomography - computed tomography ({sup 18}F-FDG PET-CT) is a major contributor of radiation. Twenty Ewing sarcoma patients diagnosed in Norway in 2005-2012 met the inclusion criteria (age <30 years, operable disease, uncomplicated chemotherapy and surgery, no metastasis or residual disease within a year of diagnosis). Radiation doses from all imaging during the first year were calculated for each patient. The mean estimated cumulative radiation dose for all patients was 34 mSv (range: 6-70), radiography accounting for 3 mSv (range: 0.2-12), CT for 13 mSv (range: 2-28) and nuclear medicine for 18 mSv (range: 2-47). For the patients examined with PET-CT, the mean estimated cumulative effective dose was 38 mSv, of which PET-CT accounted for 14 mSv (37%). There was large variation in number and type of examinations performed and also in estimated cumulative radiation dose. The mean radiation dose for patients examined with PET-CT was 23% higher than for patients not examined with PET-CT. (orig.)

  18. Estimated cumulative radiation dose received by diagnostic imaging during staging and treatment of operable Ewing sarcoma 2005-2012

    International Nuclear Information System (INIS)

    Johnsen, Boel; Fasmer, Kristine Eldevik; Boye, Kjetil; Rosendahl, Karen; Aukland, Stein Magnus; Trovik, Clement; Biermann, Martin

    2017-01-01

    Patients with Ewing sarcoma are subject to various diagnostic procedures that incur exposure to ionising radiation. To estimate the radiation doses received from all radiologic and nuclear imaging episodes during diagnosis and treatment, and to determine whether 18 F-fluorodeoxyglucose positron emission tomography - computed tomography ( 18 F-FDG PET-CT) is a major contributor of radiation. Twenty Ewing sarcoma patients diagnosed in Norway in 2005-2012 met the inclusion criteria (age <30 years, operable disease, uncomplicated chemotherapy and surgery, no metastasis or residual disease within a year of diagnosis). Radiation doses from all imaging during the first year were calculated for each patient. The mean estimated cumulative radiation dose for all patients was 34 mSv (range: 6-70), radiography accounting for 3 mSv (range: 0.2-12), CT for 13 mSv (range: 2-28) and nuclear medicine for 18 mSv (range: 2-47). For the patients examined with PET-CT, the mean estimated cumulative effective dose was 38 mSv, of which PET-CT accounted for 14 mSv (37%). There was large variation in number and type of examinations performed and also in estimated cumulative radiation dose. The mean radiation dose for patients examined with PET-CT was 23% higher than for patients not examined with PET-CT. (orig.)

  19. Value of 100 kVp scan with sinogram-affirmed iterative reconstruction algorithm on a single-source CT system during whole-body CT for radiation and contrast medium dose reduction: an intra-individual feasibility study.

    Science.gov (United States)

    Nagayama, Y; Nakaura, T; Oda, S; Tsuji, A; Urata, J; Furusawa, M; Tanoue, S; Utsunomiya, D; Yamashita, Y

    2018-02-01

    To perform an intra-individual investigation of the usefulness of a contrast medium (CM) and radiation dose-reduction protocol using single-source computed tomography (CT) combined with 100 kVp and sinogram-affirmed iterative reconstruction (SAFIRE) for whole-body CT (WBCT; chest-abdomen-pelvis CT) in oncology patients. Forty-three oncology patients who had undergone WBCT under both 120 and 100 kVp protocols at different time points (mean interscan intervals: 98 days) were included retrospectively. The CM doses for the 120 and 100 kVp protocols were 600 and 480 mg iodine/kg, respectively; 120 kVp images were reconstructed with filtered back-projection (FBP), whereas 100 kVp images were reconstructed with FBP (100 kVp-F) and the SAFIRE (100 kVp-S). The size-specific dose estimate (SSDE), iodine load and image quality of each protocol were compared. The SSDE and iodine load of 100 kVp protocol were 34% and 21%, respectively, lower than of 120 kVp protocol (SSDE: 10.6±1.1 versus 16.1±1.8 mGy; iodine load: 24.8±4versus 31.5±5.5 g iodine, pquality. Copyright © 2017 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

  20. The protection of operating personnel in nuclear power plants against the risk of nuclear incidents and ionizing radiation arising from normal operation of the plant. Rules and problems

    International Nuclear Information System (INIS)

    Ortore, F.; Scalera, D.

    1980-03-01

    After an analysis of the nuclear third party liability insurance policy to be taken out in Italy in implementation of Act no. 1860 of 31 December 1962 and Decree No. 519 of 10 May 1979, the collective policy against radiation injuries taken out for operating personnel in nuclear installations is described. The author is in favour of further harmonization of the legal system presently in force in this respect. (NEA) [fr

  1. Compatibility of advanced tokamak plasma with high density and high radiation loss operation in JT-60U

    International Nuclear Information System (INIS)

    Takenaga, H.; Asakura, N.; Kubo, H.; Higashijima, S.; Konoshima, S.; Nakano, T.; Oyama, N.; Ide, S.; Fujita, T.; Takizuka, T.; Kamada, Y.; Miura, Y.; Porter, G.D.; Rognlien, T.D.; Rensink, M.E.

    2005-01-01

    Compatibility of advanced tokamak plasmas with high density and high radiation loss has been investigated in both reversed shear (RS) plasmas and high β p H-mode plasmas with a weak positive shear on JT-60U. In the RS plasmas, the operation regime is extended to high density above the Greenwald density (n GW ) with high confinement (HH y2 >1) and high radiation loss fraction (f rad >0.9) by tailoring the internal transport barriers (ITBs). High confinement of HH y2 =1.2 is sustained even with 80% radiation from the main plasma enhanced by accumulated metal impurity. The divertor radiation is enhanced by Ne seeding and the ratio of the divertor radiation to the total radiation is increased from 20% without seeding to 40% with Ne seeding. In the high β p H-mode plasmas, high confinement (HH y2 =0.96) is maintained at high density (n-bar e /n GW =0.92) with high radiation loss fraction (f rad ∼1) by utilizing high-field-side pellets and Ar injections. The high n-bar e /n GW is obtained due to a formation of clear density ITB. Strong core-edge parameter linkage is observed, as well as without Ar injection. In this linkage, the pedestal β p , defined as β p ped =p ped /(B p 2 /2μ 0 ) where p ped is the plasma pressure at the pedestal top, is enhanced with the total β p . The radiation profile in the main plasma is peaked due to Ar accumulation inside the ITB and the measured central radiation is ascribed to Ar. The impurity transport analyses indicate that Ar accumulation by a factor of 2 more than the electron, as observed in the high β p H-mode plasma, is acceptable even with peaked density profile in a fusion reactor for impurity seeding. (author)

  2. Search for molecular bremsstrahlung radiation signals in Ku band with coincidental operations of radio telescopes with air shower detectors

    Directory of Open Access Journals (Sweden)

    Fukushima Masaki

    2013-06-01

    Full Text Available Microwave radiation from extensive air showers is expected to provide a new technique to observe UHECR. We insatlled and operate radio telescopes in Osaka and at Telescope Array site in Utah, USA. In Osaka, we are coincidentally operating two Ku band radio telescopes with an air shower array which consists of nine plastic scintillators with about 10 m separation. In Utah, we installed two telescopes just beside the Black Rock Mesa fluorescence detector (FD station of the Telescope Array experiment, and we operated the radio telescopes coincidentally with FD event triggers. We report the experimental setups and the results of these measurements.

  3. The effect of time to post-operative weightbearing on functional and clinical outcomes in adults with a displaced intra-articular calcaneal fracture; A systematic review and pooled analysis.

    Science.gov (United States)

    De Boer, A Siebe; Van Lieshout, Esther M M; Van Moolenbroek, Gerson; Den Hartog, Dennis; Verhofstad, Michael H J

    2018-02-21

    Post-operative weightbearing guidelines for displaced intra-articular calcaneal fractures (DIACF) have been pragmatically developed in the past, however hardly adapted to current health care insights. A period of six to nine weeks of non-weightbearing is usually recommended. It is unknown whether an earlier start of weightbearing is advisable. The primary aim was to evaluate the effect of time to post-operative weightbearing on Böhler's angle. Secondary aims were to determine the effect on functional outcome (e.g., The American Orthopedic Foot and Ankle Society Scale), post-operative pain score, complications (e.g., infections, nonunion, implant removal), and revision surgeries. Finally, the effect of bone void filling on these outcomes was investigated. A literature search was performed on January 24, 2017 in the Cochrane Library, Medline Ovid, Embase, Web of Science, Google Scholar, and CINAHL. Studies reporting on operatively treated patients with a DIACF and time to weightbearing were eligible for inclusion. Studies were excluded when not reporting primary data, solely reporting on open fractures, bilateral fractures, or polytrauma patients. Based upon the time to starting partial weightbearing, patient cohorts were stratified into very early (0-4 weeks), early (4-6 weeks), intermediate (6-8 weeks), or late (8-12 weeks) start of partial weightbearing. Two investigators extracted data independently using a predefined data sheet. After applying exclusion criteria, 72 studies remained eligible for analysis. Böhler's and Gissane's angles, calcaneal height, AOFAS, pain scores, and complications had overlapping confidence intervals in all weightbearing groups. The adverse sequelae which are assumed to be associated with starting partial weightbearing already within six weeks after internal fixation of calcaneal fractures, is not supported by literature data. This systematic review suggests that early weightbearing does not result in impaired outcomes compared with

  4. Progress in Space Weather Modeling and Observations Needed to Improve the Operational NAIRAS Model Aircraft Radiation Exposure Predictions

    Science.gov (United States)

    Mertens, C. J.; Kress, B. T.; Wiltberger, M. J.; Tobiska, W.; Xu, X.

    2011-12-01

    The Nowcast of Atmospheric Ionizing Radiation for Aviation Safety (NAIRAS) is a prototype operational model for predicting commercial aircraft radiation exposure from galactic and solar cosmic rays. NAIRAS predictions are currently streaming live from the project's public website, and the exposure rate nowcast is also available on the SpaceWx smartphone app for iPhone, IPad, and Android. Cosmic rays are the primary source of human exposure to high linear energy transfer radiation at aircraft altitudes, which increases the risk of cancer and other adverse health effects. Thus, the NAIRAS model addresses an important national need with broad societal, public health and economic benefits. The processes responsible for the variability in the solar wind, interplanetary magnetic field, solar energetic particle spectrum, and the dynamical response of the magnetosphere to these space environment inputs, strongly influence the composition and energy distribution of the atmospheric ionizing radiation field. During the development of the NAIRAS model, new science questions were identified that must be addressed in order to obtain a more reliable and robust operational model of atmospheric radiation exposure. Addressing these science questions require improvements in both space weather modeling and observations. The focus of this talk is to present these science questions, the proposed methodologies for addressing these science questions, and the anticipated improvements to the operational predictions of atmospheric radiation exposure. The overarching goal of this work is to provide a decision support tool for the aviation industry that will enable an optimal balance to be achieved between minimizing health risks to passengers and aircrew while simultaneously minimizing costs to the airline companies.

  5. Operator radiation exposure and physical discomfort during a right versus left radial approach for coronary interventions: a randomized evaluation.

    Science.gov (United States)

    Kado, Herman; Patel, Ambar M; Suryadevara, Siva; Zenni, Martin M; Box, Lyndon C; Angiolillo, Dominick J; Bass, Theodore A; Guzman, Luis A

    2014-07-01

    This study sought to assess radiation exposure and operator discomfort when using left radial approach (LRA) versus right radial approach (RRA) for coronary diagnostic and percutaneous interventions. The transradial approach is increasingly being adopted as the preferred vascular access for coronary interventions. Currently, most are performed using an RRA. This is in part due to the perceived increased operator physical discomforts as well increased radiation exposure with an LRA. One hundred patients were randomized to an LRA or RRA. Each operator (n = 5) had an independent randomization process, and patients were stratified according to obesity status. Operator radiation was measured using separate sets of radiation dosimeter badges placed externally on the head and thyroid and internally on the sternum. Operator physical discomfort was surveyed at 2 time points: during vascular access and at the end of the procedure. Moderate to severe physical discomfort was defined as a score of >4. There were no significant differences in baseline and procedural variables between groups. There was a significant increase in external radiation exposure using the RRA versus LRA (head: median: 6.12 [interquartile range (IQR): 2.6 to 16.6] mRems vs. median: 12.0 [IQR: 6.4 to 22.0] mRems, p = 0.02; thyroid: median: 10.10 [IQR: 4.3 to 25] mRems vs. median: 18.70 [IQR: 11.0 to 38] mRems, p = 0.001). More discomfort was reported with the LRA during access (LRA: 22% vs. RRA: 4%; p = 0.017), but not during the procedure (LRA: 10.0% vs. RRA: 4.0%, p = 0.43). This difference was almost entirely noted in obese patients (LRA: 30.0% vs. RRA: 3.7%, p = 0.005). LRA is as effective as RRA, showing a safer profile with decreased radiation exposure to the operator, at the expense of more operator discomfort only during vascular access and limited to obese patients. Copyright © 2014 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  6. The implementation of the operational dose quantities into radiation protection dosimetry (NRPB Association)

    International Nuclear Information System (INIS)

    O'Riordan, M.C.; Chartier, J.L.

    1993-01-01

    The main objectives of this project are to improve the measurement of spectral and angular distributions of external radiations in the workplace and to examine the implications of these measurements for personal dosimetry. They include measurement techniques for X-ray, γ-radiation and neutron radiation, performance testing of personal dosemeters, the implications of spectral and spatial distributions measurements on personal dosimetry. (R.P.)

  7. Three-dimensional data assimilation and reanalysis of radiation belt electrons: Observations over two solar cycles, and operational forecasting.

    Science.gov (United States)

    Kellerman, A. C.; Shprits, Y.; Kondrashov, D. A.; Podladchikova, T.; Drozdov, A.; Subbotin, D.; Makarevich, R. A.; Donovan, E.; Nagai, T.

    2015-12-01

    Understanding of the dynamics in Earth's radiation belts is critical to accurate modeling and forecasting of space weather conditions, both which are important for design, and protection of our space-borne assets. In the current study, we utilize the Versatile Electron Radiation Belt (VERB) code, multi-spacecraft measurements, and a split-operator Kalman filter to recontructe the global state of the radiation belt system in the CRRES era and the current era. The reanalysis has revealed a never before seen 4-belt structure in the radiation belts during the March 1991 superstorm, and highlights several important aspects in regards to the the competition between the source, acceleration, loss, and transport of particles. In addition to the above, performing reanalysis in adiabatic coordinates relies on specification of the Earth's magnetic field, and associated observational, and model errors. We determine the observational errors for the Kalman filter directly from cross-spacecraft phase-space density (PSD) conjunctions, and obtain the error in VERB by comparison with reanalysis over a long time period. Specification of errors associated with several magnetic field models provides an important insight into the applicability of such models for radiation belt research. The comparison of CRRES area reanalysis with Van Allen Probe era reanalysis allows us to perform a global comparison of the dynamics of the radiation belts during different parts of the solar cycle and during different solar cycles. The data assimilative model is presently used to perform operational forecasts of the radiation belts (http://rbm.epss.ucla.edu/realtime-forecast/).

  8. A Radiation Hard Multi-Channel Digitizer ASIC for Operation in the Harsh Jovian Environment

    Science.gov (United States)

    Aslam, Shahid; Aslam, S.; Akturk, A.; Quilligan, G.

    2011-01-01

    ultimately impact the surface of Europa after the mission is completed. The current JEO mission concept includes a range of instruments on the payload, to monitor dynamic phenomena (such as Io's volcanoes and Jupiters atmosphere), map the Jovian magnetosphere and its interactions with the Galilean satellites, and characterize water oceans beneath the ice shells of Europa and Ganymede. The payload includes a low mass (3.7 Kg) and low power (ASIC that resides very close to the thermopile linear array outputs. Both the thermopile array and the MCD ASIC will need to show full functionality within the harsh Jovian radiation environment, operating at cryogenic temperatures, typically 150 K to 170 K. In the following, a radiation mitigation strategy together with a low risk Radiation-Hardened-By-Design (RHBD) methodology using commercial foundry processes is given for the design and manufacture of a MCD ASIC that will meet this challenge.

  9. Relationships between the operator's radiation protection expert and the radiation protection expert belonging to an external company

    International Nuclear Information System (INIS)

    Gravelotte, D.

    2008-01-01

    The radiation protection expert (PCR in French for Personne Competente en Radioprotection) is a central actor in the organization of radioprotection. Such a person is required within radioprotection departments of basic nuclear installations as well in external companies intervening in these installations. After having recalled that relationship between these both experts is promoted by the legal framework, the author describes how this relationship is planned in the Paluel French nuclear power station. He indicates the type of data and information concerning the power station activities which are exchanged between them. He also presents the actions which have been defined to promote this relationship

  10. Pre- and/or Intra-Operative Prescription of Diuretics, but Not Renin-Angiotensin-System Inhibitors, Is Significantly Associated with Acute Kidney Injury after Non-Cardiac Surgery: A Retrospective Cohort Study.

    Science.gov (United States)

    Tagawa, Miho; Ogata, Ai; Hamano, Takayuki

    2015-01-01

    Pre- and/or intra-operative use of diuretics, angiotensin-converting enzyme inhibitors (ACE-I) or angiotensin II receptor blockers (ARB) constitutes a potentially modifiable risk factor for postoperative acute kidney injury (AKI). It has been studied whether use of these drugs predicts AKI after cardiac surgery. The objective of this study was to examine whether administration of these agents was independently associated with AKI after non-cardiac surgery. This was a retrospective observational study. Inclusion criteria were adult patients (age ≥ 18) who underwent non-cardiac surgery under general anesthesia from 2007 to 2009 at Kyoto Katsura Hospital. Exclusion criteria were urological surgery, missing creatinine values, and preoperative dialysis. The exposures of interest were pre- and/or intra-operative use of diuretics or ACE-I/ARB. Outcome variables were postoperative AKI as defined by the AKI Network (increase in creatinine ≥ 0.3 mg/dL or 150% within 48 hours, or urine output 6 hours). Multivariable logistic regression analyses were conducted and adjusted for potential confounders. Propensity scores (PS) for receiving diuretics or ACE-I/ARB therapy were estimated and PS adjustment, PS matching, and inverse probability weighting were performed. There were 137 AKI cases (5.0%) among 2,725 subjects. After statistical adjustment for patient and surgical characteristics, odds (95% CI) of postoperative AKI were 2.07 (1.10-3.89) (p = 0.02) and 0.89 (0.56-1.42) (p = 0.63) in users of diuretics and ACE-I/ARB, respectively, compared with non-users. PS adjustment, PS matching, and inverse probability weighting yielded similar results. The effect size of diuretics was significantly greater in the patients with lower propensity for diuretic use (p for interaction diuretics, but not ACE-I/ARB, was independently associated with postoperative AKI after non-cardiac surgery, especially in patients with low propensity for diuretic use. It might be reasonable to withhold

  11. Report detailing personal radiation dose statistics resulting from operations of Nuclear Electric plc during 1995

    International Nuclear Information System (INIS)

    Brodie, P.; Varcoe, I.H.

    1996-03-01

    This report provides details of doses received by all Nuclear Electric plc employees and contractors whose work involved exposure to ionising radiations at Nuclear Electric plc sites during the calendar year 1995. Details of collective doses for previous years for the nuclear licensed sites are also included. It should be noted that Nuclear Electric plc was formed on 1 April 1990 as one of the successor companies to the Central Electricity Generating Board. This report will be the last to be produced by Nuclear Electric plc, as, from 31 March 1996, the AGR and PWR business and assets of Nuclear Electric plc transferred to Nuclear Electric Ltd and Nuclear Electric plc now trades as Magnox Electric plc. It is intended that these companies will separately produce their own Annual Dose Statistics Reports in the future. All results are compiled from the information supplied by the sites to the Central Dose Record Service (NE plc Approved Dosimetry Service for Co-ordination and Record Keeping) via Approved Dosimetry Services for Assessments. For all sites the total annual whole body dose equivalent for 1995 is 5.67 manSv which includes 0.16 manSv as the contribution for commissioning of Sizewell B. The total collective dose varies from year to year for operational reasons (see below). Table 4 shows that over a period of 6 years there has been a general decreasing trend in the collective dose. The collective dose for 1995 was not significantly different from the 1994 value. In 1995 no employee received a dose in excess of 15 mSv and less than 1% of Nuclear Electric plc staff on licensed sites received a dose of more than 5 mSv. (UK)

  12. Non-LTE radiative transfer with lambda-acceleration - Convergence properties using exact full and diagonal lambda-operators

    Science.gov (United States)

    Macfarlane, J. J.

    1992-01-01

    We investigate the convergence properties of Lambda-acceleration methods for non-LTE radiative transfer problems in planar and spherical geometry. Matrix elements of the 'exact' A-operator are used to accelerate convergence to a solution in which both the radiative transfer and atomic rate equations are simultaneously satisfied. Convergence properties of two-level and multilevel atomic systems are investigated for methods using: (1) the complete Lambda-operator, and (2) the diagonal of the Lambda-operator. We find that the convergence properties for the method utilizing the complete Lambda-operator are significantly better than those of the diagonal Lambda-operator method, often reducing the number of iterations needed for convergence by a factor of between two and seven. However, the overall computational time required for large scale calculations - that is, those with many atomic levels and spatial zones - is typically a factor of a few larger for the complete Lambda-operator method, suggesting that the approach should be best applied to problems in which convergence is especially difficult.

  13. Hybrid radiation background monitoring in operational control and forecasting of environmental contamination by nuclear power station discharges

    International Nuclear Information System (INIS)

    Ermeev, I.S.; Eremenko, V.A.; Makarov, Y.A.; Matueev, V.V.; Zhernov, V.S.

    1986-01-01

    Rapid developments in nuclear power have stimulated research on monitoring and forecasting environmental radiation pollution (ERP), and in particular the amounts, compositions, and distributions of radionuclides in the environment. A conceptual model is presented for hybrid environmental radiation pollution monitoring. When there is an emergency, the model operates in a fashion most closely corresponding to the actual meteorological conditions, and the ERP data given by the model enable one to distinguish changes due to the man-made component from random fluctuations in the natural background. The measurement system in general includes mobile and stationary data-acquisition facilities linked by wire or radio to the central point. The system also accumulates and stores data on the radiation environment, which are edited on the basis of radioactive, chemical, and other transformations. The purpose of hybrid monitoring is ultimately to analyze trends in order to detect elevated discharges and thus to output data to the regional monitoring system

  14. Correlation between scatter radiation dose at the height of the operators eye and dose to patient for different angiographies projections

    Energy Technology Data Exchange (ETDEWEB)

    Leyton, F.; Nogueira, M. S.; Da Silva, T. A. [Centro de Desenvolvimento da Tecnologia Nuclear / CNEN, Post-graduation in Sciences and Technology of Radiations, Minerals and Materials, Pte. Antonio Carlos No. 6627, Belo Horizonte 31270-901, Minas Gerais (Brazil); Gubolino, L.; Pivetta, M. R. [Hospital dos Fornecedores de Cana de Piracicaba, Av. Barao de Valenca 616, 13405-233 Piracicaba (Brazil); Ubeda, C., E-mail: leyton.fernando@gmail.com [Tarapaca University, Health Sciences Faculty, Radiological Sciences Center, Av. Gral. Velasquez 1775, 1000007 Arica, Arica and Parinacota (Chile)

    2015-10-15

    Cases of radiation induced cataract among cardiology professionals have been reported in studies. In view of evidence of radiation injuries, the ICRP recommends limiting the radiation dose to the lens to 20 mSv per year for occupational exposure. The aim of this works was to report scattered radiation doses at the height of the operators eye in an interventional cardiology facility from procedures performed without use of radiation protection devices, correlated with different angiographic projections and operational modes. Measurements were made in a cardiac laboratory with an angiography X-ray system GE equipped with flat-panel detector. PMMA plates of 30 x 30 x 5 cm were used to simulate a patient with a thickness of 20 cm. Two fluoroscopy modes (low and normal, 15 frame/s), cine mode 15 frame/s. Four angiographic projections anterior posterior (Ap), lateral (Lat), left anterior oblique caudal (spider) and left anterior oblique cranial (Lao-45/cra-30) and a cardiac protocol for patient between 70 to 90 kg was used. Measurements of phantom entrance doses rate and scatter doses rate were performed with two Unfors Xi plus. The detector measuring scatter radiation was positioned at the usual distance of the cardiologists eyes during working conditions (1 m from the isocenter and 1.7 m from the floor). There is a good linear correlation between the kerma-area product and scatter dose at the lens. An experimental correlation factor of 2.3; 12.0; 12.2 and 17.6 μSv/Gy cm{sup 2} were found for the Ap, Lao/cra, spider and Lat projections, respectively. The entrance dose of PMMA for fluoroscopy low, medium and cine was 13, 39 and 282 mGy/min, respectively to Ap. (Author)

  15. Correlation between scatter radiation dose at the height of the operators eye and dose to patient for different angiographies projections

    International Nuclear Information System (INIS)

    Leyton, F.; Nogueira, M. S.; Da Silva, T. A.; Gubolino, L.; Pivetta, M. R.; Ubeda, C.

    2015-10-01

    Cases of radiation induced cataract among cardiology professionals have been reported in studies. In view of evidence of radiation injuries, the ICRP recommends limiting the radiation dose to the lens to 20 mSv per year for occupational exposure. The aim of this works was to report scattered radiation doses at the height of the operators eye in an interventional cardiology facility from procedures performed without use of radiation protection devices, correlated with different angiographic projections and operational modes. Measurements were made in a cardiac laboratory with an angiography X-ray system GE equipped with flat-panel detector. PMMA plates of 30 x 30 x 5 cm were used to simulate a patient with a thickness of 20 cm. Two fluoroscopy modes (low and normal, 15 frame/s), cine mode 15 frame/s. Four angiographic projections anterior posterior (Ap), lateral (Lat), left anterior oblique caudal (spider) and left anterior oblique cranial (Lao-45/cra-30) and a cardiac protocol for patient between 70 to 90 kg was used. Measurements of phantom entrance doses rate and scatter doses rate were performed with two Unfors Xi plus. The detector measuring scatter radiation was positioned at the usual distance of the cardiologists eyes during working conditions (1 m from the isocenter and 1.7 m from the floor). There is a good linear correlation between the kerma-area product and scatter dose at the lens. An experimental correlation factor of 2.3; 12.0; 12.2 and 17.6 μSv/Gy cm 2 were found for the Ap, Lao/cra, spider and Lat projections, respectively. The entrance dose of PMMA for fluoroscopy low, medium and cine was 13, 39 and 282 mGy/min, respectively to Ap. (Author)

  16. Environmental radiation control and quality management system in design and operation of sealed radioactive sources

    International Nuclear Information System (INIS)

    Hussein, A.Z.

    2007-01-01

    New environmental regulations and radiation safety standards are being implemented almost daily to ensure radiation safety, in particular for practices causing exposures to undue radiation doses. A particular emphasis of real challenge for organizations and users of radiation sources has to be for proper radiological safety assessment and is becoming cost effectively to be prepared for auditing. Special concern for the environment is of global . nature, and hence environmental auditing has been and will continue to be an essential practice for improving the environment and for meeting the relevant regulations and standards. In general, most facilities that deal with radioactive sources undertake strict safety measures in terms of personnel radiation protection, handling procedures and security. Hence, those measures should comply with the requirements of the environmental protection standards. Accordingly, a successful quality management system must balance realities of organization and personnel in achieving quality objectives. Organizational principles are found in the technical aspects of' quality management, such as, charting, requirements, measurements, procedures, ... , etc. Human principles are found in the communication side of quality management (e.g. meetings, ,decision making, ,teams, ... , etc). The quality management must understand and balance skills needed to blend them together. Large gamma irradiators present a high potential radiation hazard to the surrounding environment, since the amount of radioactivity is of the order of (P Bq) and a very high dose rates are produced during irradiation. Application of environmental radiation control deemed by regulatory authority and a proper quality management system by the utility would serve public health and safety

  17. Initial experience with an 11 MeV self-shielded medical cyclotron on operation and radiation safety

    Science.gov (United States)

    Pant, G. S.; Senthamizhchelvan, S.

    2007-01-01

    A self-shielded medical cyclotron (11 MeV) was commissioned at our center, to produce positron emitters, namely, 18F, 15O, 13N and 11C for positron emission tomography (PET) imaging. Presently the cyclotron has been exclusively used for the production of 18F- for 18F-FDG imaging. The operational parameters which influence the yield of 18F- production were monitored. The radiation levels in the cyclotron and radiochemistry laboratory were also monitored to assess the radiation safety status in the facility. The target material, 18O water, is bombarded with proton beam from the cyclotron to produce 18F- ion that is used for the synthesis of 18F-FDG. The operational parameters which influence the yield of 18F- were observed during 292 production runs out of a total of more than 400 runs. The radiation dose levels were also measured in the facility at various locations during cyclotron production runs and in the radiochemistry laboratory during 18F-FDG syntheses. It was observed that rinsing the target after delivery increased the number of production runs in a given target, as well as resulted in a better correlation between the duration of bombardment and the end of bombardment 18F- activity with absolutely clean target after being rebuilt. The radiation levels in the cyclotron and radiochemistry laboratory were observed to be well within prescribed limits with safe work practice. PMID:21157531

  18. Initial experience with an 11 MeV self-shielded medical cyclotron on operation and radiation safety

    International Nuclear Information System (INIS)

    Pant, G.S.; Senthamizhchelvan, S.

    2007-01-01

    A self-shielded medical cyclotron (11 MeV) was commissioned at our center, to produce positron emitters, namely, 18 F, 15 O, 13 N and 11 C for positron emission tomography (PET) imaging. Presently the cyclotron has been exclusively used for the production of 18 F for 18 F-FDG imaging. The operational parameters which influence the yield of 18 F-production were monitored. The radiation levels in the cyclotron and radiochemistry laboratory were also monitored to assess the radiation safety status in the facility. The target material, 18 O water, is bombarded with proton beam from the cyclotron to produce 18 F ion that is used for the synthesis of 18 F-FDG. The operational parameters which influence the yield of 18 F- were observed during 292 production runs out of a total of more than 400 runs. The radiation dose levels were also measured in the facility at various locations during cyclotron production runs and in the radiochemistry laboratory during 18 F-FDG syntheses. It was observed that rinsing the target after delivery increased the number of production runs in a given target, as well as resulted in a better correlation between the duration of bombardment and the end of bombardment 18 F activity with absolutely clean target after being rebuilt. The radiation levels in the cyclotron and radiochemistry laboratory were observed to be well within prescribed limits with safe work practice. (author)

  19. Solar radiation (PAR, UV-A, UV-B) penetration in a shallow maturation pond operating in a tropical climate.

    Science.gov (United States)

    Dias, Daniel F C; von Sperling, Marcos

    2017-07-01

    Solar radiation is considered the primary route for disinfection of pathogenic bacteria in maturation ponds. There is scarce information on depth profiling and attenuation of photosynthetically active radiation (PAR), UV-A and UV-B in shallow maturation ponds operating in tropical climates. Measurements of solar irradiance of the three wavelength ranges, together with turbidity, have been acquired from different depths for over 1 year in a shallow maturation pond (44 cm of depth) operating in Brazil. UV-A and UV-B were still detected at 10 cm from the surface, but from 15 cm both were undetectable. PAR was still detected at 30 cm of depth. Irradiation attenuation showed to be related to turbidity. Attenuation coefficients were calculated and simple models without turbidity (traditional structure) or including log 10 of turbidity are proposed for predicting PAR irradiance attenuation as a function of depth.

  20. Direct ultimate disposal of spent fuel DEAB. Radiation doses from specified normal operation

    International Nuclear Information System (INIS)

    Raitz von Frentz, R.

    1992-08-01

    The collective dose to the personnel from external irradiation and inhalation is below 10% of the occupational dose limit for personnel belonging to category A defined according to section 49 StrlSchV (German radiation protection ordinance). The potential radiation exposure of the population, adults and infants, is derived via the airborne exposure pathway. The results show that the derived doses are markedly below the dose limits defined in section 45 StrlSchV, despite the very conservative figures used for the emission source strength. The radiation dose to the lungs of an infant, for instance, is derived to be below 4% of the dose limit. (HP) [de

  1. Intra-industry trade

    NARCIS (Netherlands)

    J.G.M. van Marrewijk (Charles)

    2008-01-01

    textabstractIntra-industry trade arises if a country simultaneously imports and exports similar types of goods or services. Similarity is identified here by the goods or services being classified in the same “sector”. Suppose, for the sake of argument, that we focus on the sector “cars”.

  2. Intra-articulaire calcaneusfracturen

    NARCIS (Netherlands)

    T. Schepers (Tim); P. Patka (Peter)

    2008-01-01

    textabstractABSTRACT About 0.6% of all fractures is an intra-articular calcaneal fracture. Patients often have additional injuries, and returning to work can take up to one year. The diagnostics consist of plain, lateral and axial, radiographs of the calcaneus. In addition a CT-scan is performed in

  3. Intra Partum Foetal Distress

    Directory of Open Access Journals (Sweden)

    J Kubheka

    1985-09-01

    Full Text Available The occurrence of neonatal asphyxia at Baragwanath Hospital is a daily problem. The question was raised as to whether intra partum foetal distress, apgar scoring at birth and the biochemical analysis of blood acid base status from the chorionic arteries can predict any short-term neurological defects.

  4. Radiation dose to the operator during vertebroplasty: prospective comparison of the use of 1-cc syringes versus an injection device.

    Science.gov (United States)

    Kallmes, David F; O, Erwin; Roy, Soma Sinha; Piccolo, Richard G; Marx, William F; Lee, Jae K; Jensen, Mary E

    2003-01-01

    Percutaneous vertebroplasty procedures require relatively long durations of fluoroscopic guidance, which might lead to substantial radiation dose to operators. Specialized injection devices have been proposed to limit operator exposure. Our purpose was to compare the radiation dose to the operator's hands during vertebroplasty when using 1-cc syringes versus that when using an injection device. Radiation dosimeters were worn on the left wrist during 39 vertebroplasty injection procedures in 25 patients. Cases were alternated between the use of 1-cc syringes (19 procedures) and the use of an injection device (20 procedures). For each procedure, one dosimeter was worn throughout the procedure, both during needle placement and injection, and a second dosimeter was worn during the injection phase only. Mean doses for the whole case and mean doses for the injection procedure alone were compared between groups. Mean whole case dose was 128 +/- 161 mrem (range, 0-660 mrem) for the 1-cc syringe group versus 98 +/- 90 mrem (range, 0-340 mrem) for the injection device group (P =.23). Mean dose during injection was 100 +/- 145 mrem (range, 0-660 mrem) for the 1-cc syringe group versus 55 +/- 43 mrem (range, 0-130 mrem) for the injection device group (P =.09). Three of 19 1-cc syringe cases yielded zero dose, compared with four of 20 injection device cases. Duration of injection was markedly different between groups, with mean injection times of 4.2 and 7.5 min for 1-cc syringe and injection device cases, respectively (P device groups, respectively (P =.002). The use of an injection device significantly decreased the radiation dose to the operator's extremity per unit time of injection. However, total dose per injection was equivalent between groups because of significantly longer injection duration for the injection device cohort.

  5. Radiation

    International Nuclear Information System (INIS)

    Davidson, J.H.

    1986-01-01

    The basic facts about radiation are explained, along with some simple and natural ways of combating its ill-effects, based on ancient healing wisdom as well as the latest biochemical and technological research. Details are also given of the diet that saved thousands of lives in Nagasaki after the Atomic bomb attack. Special comment is made on the use of radiation for food processing. (U.K.)

  6. Operational specification and forecasting advances for Dst, LEO thermospheric densities, and aviation radiation dose and dose rate

    Science.gov (United States)

    Tobiska, W. Kent

    Space weather’s effects upon the near-Earth environment are due to dynamic changes in the energy transfer processes from the Sun’s photons, particles, and fields. Of the space environment domains that are affected by space weather, the magnetosphere, thermosphere, and even troposphere are key regions that are affected. Space Environment Technologies (SET) has developed and is producing innovative space weather applications. Key operational systems for providing timely information about the effects of space weather on these domains are SET’s Magnetosphere Alert and Prediction System (MAPS), LEO Alert and Prediction System (LAPS), and Automated Radiation Measurements for Aviation Safety (ARMAS) system. MAPS provides a forecast Dst index out to 6 days through the data-driven, redundant data stream Anemomilos algorithm. Anemomilos uses observational proxies for the magnitude, location, and velocity of solar ejecta events. This forecast index is used by satellite operations to characterize upcoming geomagnetic storms, for example. In addition, an ENLIL/Rice Dst prediction out to several days has also been developed and will be described. LAPS is the SET fully redundant operational system providing recent history, current epoch, and forecast solar and geomagnetic indices for use in operational versions of the JB2008 thermospheric density model. The thermospheric densities produced by that system, driven by the LAPS data, are forecast to 72-hours to provide the global mass densities for satellite operators. ARMAS is a project that has successfully demonstrated the operation of a micro dosimeter on aircraft to capture the real-time radiation environment due to Galactic Cosmic Rays and Solar Energetic Particles. The dose and dose-rates are captured on aircraft, downlinked in real-time via the Iridium satellites, processed on the ground, incorporated into the most recent NAIRAS global radiation climatology data runs, and made available to end users via the web and

  7. Organization and operation of the Sixth International Symposium on the Natural Radiation Environment (NRE VI)

    International Nuclear Information System (INIS)

    Hopke, P.K.

    1996-01-01

    An important source of human exposure to radiation is the natural world including cosmic rays, cosmogenic radionuclides, natural terrestrial radionuclides, and radon isotopes and its decay products. Considerable effort is being expended on a worldwide basis to characterize the exposure to the natural radiation environment and determine the important pathways for the exposure to result in the dose to tissue that leads to injury and disease. The problem of background exposure to naturally occurring radioactivity has been the subject of research since the initial discovery of the radioactivity of uranium and thorium. However, with the advent of artificial sources of radiation with both benefits and harm the nature and magnitude of the natural radiation environment and the effects on various populations are important in the development of overall public health strategies as ALARA principles are applied to the situation

  8. Organization for radiation protection. Operations of the ICRP and NCRP: 1928-1974

    International Nuclear Information System (INIS)

    Taylor, L.S.

    1979-09-01

    The protection of people against the real or possible harmful effects of ionizing radiation reflects a unique combination of efforts involving art, science, engineering and philosophy. The existence of the potential hazard was recognized within a few weeks after the discovery in November 1895, of x rays, the first form of ionizing radiation known to man. Since that early time, almost continuous attention has been directed, in varying degree, to the problem of protecting man against any harmful effects of radiation, with the result that the nature of the problem and its amelioration is probably better understood than for any other toxic agent of such great value to mankind and yet of concomitant possible great harm. Hence is is felt that many valuable lessons may be learned from a detailed understanding of the methods, strategies, mistakes, and successes involved in the development of radiation protection practices that may be usefully applied in cases of other potentially harmful agents. Throughout the development of radiation protection standards, there has been steady growth in the understanding of radiation effects but many uncertainties and important differences of interpretation yet remain. Some of these points of issue will be touched upon, but their evaluation and reconciliation will not be attempted; that is the role of a treatise on radiobiology, since the ultimate solutions bear on many areas other than radiation protection. As events have shown, certain biomedical conclusions have become accepted, within the overall knowledge of the time, only to be radically altered as new knowledge has been developed. Changes in accepted conclusions have importantly influenced the philosophy and practice of radiation protection

  9. Operating devices for radiation protection: acceptable deviations from legal metrology point of view

    International Nuclear Information System (INIS)

    Soukup, T.

    2008-01-01

    The objective of this paper is to draw attention to possible discrepancies in the measuring the quantities of ionizing radiation mainly in natural environment, that cannot be explained by faulty gauges. In addition I would like to draw the attention to these issue radiation protection researchers, document that uncertainties in estimating the impact of exposure and transfer them into the language of used meters tolerances. (authors)

  10. Operating devices for radiation protection: acceptable deviations from legal metrology point of view

    International Nuclear Information System (INIS)

    Soukup, T.

    2009-01-01

    The objective of this paper is to draw attention to possible discrepancies in the measuring the quantities of ionizing radiation mainly in natural environment, that cannot be explained by faulty gauges. In addition I would like to draw the attention to these issue radiation protection researchers, document that uncertainties in estimating the impact of exposure and transfer them into the language of used meters tolerances. (authors)

  11. Dose-volume histogram parameters for predicting radiation pneumonitis using receiver operating characteristic curve

    International Nuclear Information System (INIS)

    Wang Dongqing; Zhang Jian; Li Baosheng; Sun Hongfu

    2012-01-01

    Objective: To assess the accuracy (ACC), sensitivity (SEN), and specificity (SPE) of dose-volume histogram (DVH) parameters in predicting the radiation pneumonitis (RP) using receiver operating characteristic (ROC) curve. Methods: Complete clinical data of 118 non-small cell lung cancer patients treated with three-dimensional conformal and intensity-modulated radiotherapy plus chemotherapy were included. Chi-square and logistic regression were retrospectively applied to analyze the correlations between DVH parameters [relative lung volume received ≥ 5 Gy (V 5 ), 10 Gy (V 10 ), 13 Gy (V 13 ), 20 Gy (V 20 ) and 30 Gy (V 30 ) and mean lung dose (MLD)] and grade 2 (and above) RP defined by the National Cancer Institute Common Terminology Criteria for Adverse Events, version 3.0. ROC curve was adopted to investigate the predictive ACC, SEN and SPE of potential DVH parameters associated with RP. Results: Total lungs V 5 , V 10 , V 13 , V 20 and MLD were all correlated to the development of RP (χ 2 =4.786, 5.771, 6.366, 7.367 and 6.945, P<0.05) according to univariate analysis. However, total lungs V 30 , patient characteristics (age, sex, KPS, tumor location, pathology) and treatment factors (prescription dose, radiotherapy technique, chemotherapy method and timing) were not contributors to RP. Logistic regression showed that V 20 of both lungs remains tight by associated with RP (χ 2 =10.96, OR=4.16, 95% CI 1.40 ∼ 12.36, P<0.05), although significant colinearity was found between V 20 and other DVH parameters (r=0.767-0.902, P<0.05). ROC curve confirmed that V 20 of both lungs could act as a predictor for RP (Z=2.038, P<0.05). The predictive ACC, SEN, and SPE were 0.645 (95% CI 0.498-0.793), 0.650 (95% CI 0.408-0.864), and 0.674 (95% CI 0.571-0.765), respectively. However, the positive predictive value was only 28.9%. Conclusions: V 20 of both lungs was correlated to the development of RP. It could act as a predictor for RP though the predictability is limited

  12. IR radiation characteristics of rocket exhaust plumes under varying motor operating conditions

    Directory of Open Access Journals (Sweden)

    Qinglin NIU

    2017-06-01

    Full Text Available The infrared (IR irradiance signature from rocket motor exhaust plumes is closely related to motor type, propellant composition, burn time, rocket geometry, chamber parameters and flight conditions. In this paper, an infrared signature analysis tool (IRSAT was developed to understand the spectral characteristics of exhaust plumes in detail. Through a finite volume technique, flow field properties were obtained through the solution of axisymmetric Navier-Stokes equations with the Reynolds-averaged approach. A refined 13-species, 30-reaction chemistry scheme was used for combustion effects and a k-ε-Rt turbulence model for entrainment effects. Using flowfield properties as input data, the spectrum was integrated with a line of sight (LOS method based on a single line group (SLG model with Curtis-Godson approximation. The model correctly predicted spectral distribution in the wavelengths of 1.50–5.50 μm and had good agreement for its location with imaging spectrometer data. The IRSAT was then applied to discuss the effects of three operating conditions on IR signatures: (a afterburning; (b chamber pressure from ignition to cutoff; and (c minor changes in the ratio of hydroxyl-terminated polybutadiene (HTPB binder to ammonium perchlorate (AP oxidizer in propellant. Results show that afterburning effects can increase the size and shape of radiance images with enhancement of radiation intensity up to 40%. Also, the total IR irradiance in different bands can be characterized by a non-dimensional chamber pressure trace in which the maximum discrepancy is less than 13% during ignition and engine cutoff. An increase of chamber pressure can lead to more distinct diamonds, whose distance intervals are extended, and the position of the first diamond moving backwards. In addition, an increase in HTPB/AP causes a significant jump in spectral intensity. The incremental rates of radiance intensity integrated in each band are linear with the increase of HTPB

  13. Radionuclides and radiation doses in heavy mineral sands and other mining operations in Mozambique

    International Nuclear Information System (INIS)

    Carvalho, F. P.; Matine, O. F.; Taimo, S.; Oliveira, J. M.; Silva, L.; Malta, M.

    2014-01-01

    Sites at the littoral of Mozambique with heavy mineral sands exploited for ilmenite, rutile and zircon and inland mineral deposits exploited for tantalite, uranium and bauxite were surveyed for ambient radiation doses, and samples were collected for the determination of radionuclide concentrations. In heavy mineral sands, 238 U and 232 Th concentrations were 70±2 and 308±9 Bq kg -1 dry weight (dw), respectively, whereas after separation of minerals, the concentrations in the ilmenite fraction were 2240±64 and 6125±485 Bq kg -1 (dw), respectively. Tantalite displayed the highest concentrations with 44 738±2474 Bq kg -1 of 238 U. Radiation exposure of workers in mining facilities is likely to occur at levels above the dose limit for members of the public (1 mSv y -1 ) and therefore radiation doses should be assessed as occupational exposures. Local populations living in these regions in general are not exposed to segregated minerals with high radionuclide concentrations. However, there is intensive traditional mining and a large number of artisan miners and their families may be exposed to radiation doses exceeding the dose limit. A radiation protection programme is therefore needed to ensure radiation protection of the public and workers of developing mining projects. (authors)

  14. Radionuclides and radiation doses in heavy mineral sands and other mining operations in Mozambique.

    Science.gov (United States)

    Carvalho, Fernando P; Matine, Obete F; Taímo, Suzete; Oliveira, João M; Silva, Lídia; Malta, Margarida

    2014-01-01

    Sites at the littoral of Mozambique with heavy mineral sands exploited for ilmenite, rutile and zircon and inland mineral deposits exploited for tantalite, uranium and bauxite were surveyed for ambient radiation doses, and samples were collected for the determination of radionuclide concentrations. In heavy mineral sands, (238)U and (232)Th concentrations were 70±2 and 308±9 Bq kg(-1) dry weight (dw), respectively, whereas after separation of minerals, the concentrations in the ilmenite fraction were 2240±64 and 6125±485 Bq kg(-1) (dw), respectively. Tantalite displayed the highest concentrations with 44 738±2474 Bq kg(-1) of (238)U. Radiation exposure of workers in mining facilities is likely to occur at levels above the dose limit for members of the public (1 mSv y(-1)) and therefore radiation doses should be assessed as occupational exposures. Local populations living in these regions in general are not exposed to segregated minerals with high radionuclide concentrations. However, there is intensive artisanal mining and a large number of artisanal miners and their families may be exposed to radiation doses exceeding the dose limit. A radiation protection programme is therefore needed to ensure radiation protection of the public and workers of developing mining projects.

  15. Intra-Operative Dosimetry in Prostate Brachytherapy

    Science.gov (United States)

    2006-11-01

    insufficient to correctly match the seeds, while a third image renders the matching problem to be of nonpolynomial complexity. We utilize the special... subpixel precision. Projected point features have a high segmentation error25 1–2 pixel but make the pose estimation problem very well constrained.27...in Eq. 2 uniquely. In this framework, the exact solution is rendered nonlin- ear and we use the iterative Newton’s optimization method to solve it

  16. Remote operation and automation of the maintenance works under the radiation field

    International Nuclear Information System (INIS)

    Asai, Takashi; Koga, Akihiko; Shirasu, Isao; Miida, Toshiro

    1983-01-01

    More than ninety per cent of the personnel radiation exposure at the nuclear power station is attributable to the maintenence works during the plant shutdown. The maintenance robots have effectively contributed in reducing the annual inspection and refueling schedule and the personnel radiation exposure. Future prospects of robotics depend on the grade of development in robot technology and plant engineering itself to accommodate such robot tools, since plant facilities and maintenance procedure today is so difficult to replace with machines due to their deversified and complexed nature. (author)

  17. Recommendations to designers aimed at minimizing radiation dose incurred in operation, maintenance, inspection and repair of light-water reactors

    International Nuclear Information System (INIS)

    1978-01-01

    In the framework of the exchange of experience between nuclear power plant operators organized by the services of the Commission of the European Communities an ad-hoc working party elaborated recommendations particularly directed to those concerned with design of light water reactor plants. The necessary design measures which should be followed to minimize radiation dose incurred in operation, maintenance, inspection and repair of such reactors are listed. The recommendations are based on recent views expressed by operating utilities within the Community. It is intended to revise these recommendations at suitable intervals in order to make use of the most recent experience and to keep the report up to date with the actual state of art in nuclear technology

  18. Design of a MGy radiation tolerant resolver-to-digital convertor IC for remotely operated maintenance in harsh environments

    Energy Technology Data Exchange (ETDEWEB)

    Leroux, Paul, E-mail: paul.leroux@kuleuven.be [KU Leuven, Dept. of Electrical Engineering (ESAT), AdvISe, Kleinhoefstraat 4, 2440 Geel (Belgium); Van Koeckhoven, Wesley; Verbeeck, Jens [KU Leuven, Dept. of Electrical Engineering (ESAT), AdvISe, Kleinhoefstraat 4, 2440 Geel (Belgium); Van Uffelen, Marco; Esqué, Salvador; Ranz, Roberto; Damiani, Carlo [Fusion for Energy, Torres Diagonal Litoral B3, Josep Pla 2, 08019 Barcelona (Spain); Hamilton, David [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul-lez-Durance (France)

    2014-10-15

    During future ITER maintenance operations, sensors and their embarked electronics will be exposed to a hostile and radioactive environment. This paper presents the design of a MGy radiation tolerant 16 bit resolver-to-digital converter (RDC) in 130 nm CMOS technology. The RDC features a Type II digital tracking loop, able to track resolvers with speeds up to 300 rps, and excitation frequencies up to 4 kHz. The RDC uses two integrated ΔΣ-analog-to-digital converters (ADCs) to digitize the resolver outputs. The 16 bit, 10 kHz ADCs utilize a correlated double sampling technique to remove radiation induced offset and 1/f-noise. The front-end features a static angular resolution of 16 bits (4.2 arcsec{sub rms}) and a resolution of 10 bits (6 arcmin{sub rms}) at a rotor speed of 100 rps. The circuit has a simulated radiation tolerance exceeding 1 MGy. It has the ability to operate under temperatures up to 125 °C, and to allow multiplexing with signals from other conventional sensors for compact, robust read-out architectures.

  19. Nuclear safety and radiation protection report of EdF's Tricastin operational hot base nuclear facilities (BCOT) - 2010

    International Nuclear Information System (INIS)

    2011-06-01

    This safety report was established under the article 21 of the French law no. 2006-686 of June 13, 2006 relative to nuclear safety and information transparency. It presents, first, the Tricastin operational hot base facility (INB no. 157, Bollene, Vaucluse (FR)), a nuclear workshop for storage and maintenance and qualification operations on some EdF equipments. Then, the nuclear safety and radiation protection measures taken regarding the facility are reviewed: nuclear safety definition, radiation protection of intervening parties, safety and radiation protection improvement paths, crisis management, external and internal controls, technical situation of facilities, administrative procedures in progress. The incidents and accidents which occurred in 2010, if some, are reported as well as the effluents discharge in the environment. Finally, The radioactive materials and wastes generated by the facility is presented and sorted by type of waste, quantities and type of conditioning. The document concludes with a glossary and a list of recommendations from the Committees for health, safety and working conditions. (J.S.)

  20. The planning, construction, and operation of a radioactive waste storage facility for an Australian state radiation regulatory authority

    Energy Technology Data Exchange (ETDEWEB)

    Wallace, J.D.; Kleinschmidt, R.; Veevers, P. [Radiation Health, Queensland (Australia)

    1995-12-31

    Radiation regulatory authorities have a responsibility for the management of radioactive waste. This, more often than not, includes the collection and safe storage of radioactive sources in disused radiation devices and devices seized by the regulatory authority following an accident, abandonment or unauthorised use. The public aversion to all things radioactive, regardless of the safety controls, together with the Not In My Back Yard (NIMBY) syndrome combine to make the establishment of a radioactive materials store a near impossible task, despite the fact that such a facility is a fundamental tool for regulatory authorities to provide for the radiation safety of the public. In Queensland the successful completion and operational use of such a storage facility has taken a total of 8 years of concerted effort by the staff of the regulatory authority, the expenditure of over $2 million (AUS) not including regulatory staff costs and the cost of construction of an earlier separate facility. This paper is a summary of the major developments in the planning, construction and eventual operation of the facility including technical and administrative details, together with the lessons learned from the perspective of the overall project.

  1. Radiation Protection and Radioactive Waste Management in the Operation of Nuclear Power Plants. Safety Guide (Spanish Edition)

    International Nuclear Information System (INIS)

    2010-01-01

    The purpose of this Safety Guide is to provide recommendations to the regulatory body, focused on the operational aspects of radiation protection and radioactive waste management in nuclear power plants, and on how to ensure the fulfilment of the requirements established in the relevant Safety Requirements publications. It will also be useful for senior managers in licensee or contractor organizations who are responsible for establishing and managing programmes for radiation protection and for the management of radioactive waste. This Safety Guide gives general recommendations for the development of radiation protection programmes at nuclear power plants. The issues are then elaborated by defining the main elements of a radiation protection programme. Particular attention is paid to area classification, workplace monitoring and supervision, application of the principle of optimization of protection (also termed the 'as low as reasonably achievable' (ALARA) principle), and facilities and equipment. This Safety Guide covers all the safety related aspects of a programme for the management of radioactive waste at a nuclear power plant. Emphasis is placed on the minimization of waste in terms of both activity and volume. The various steps in predisposal waste management are covered, namely processing (pretreatment, treatment and conditioning), storage and transport. Releases of effluents, the application of authorized limits and reference levels are discussed, together with the main elements of an environmental monitoring programme

  2. Offsite radiation doses from Hanford Operations for the years 1983 through 1987: A comparison of results calculated by two methods

    International Nuclear Information System (INIS)

    Soldat, J.K.

    1989-10-01

    This report compares the results of the calculation of potential radiation doses to the public by two different environmental dosimetric systems for the years 1983 through 1987. Both systems project the environmental movement of radionuclides released with effluents from Hanford operations; their concentrations in air, water, and foods; the intake of radionuclides by ingestion and inhalation; and, finally, the potential radiation doses from radionuclides deposited in the body and from external sources. The first system, in use for the past decade at Hanford, calculates radiation doses in terms of 50-year cumulative dose equivalents to body organs and to the whole body, based on the methodology defined in ICRP Publication 2. This system uses a suite of three computer codes: PABLM, DACRIN, and KRONIC. In the new system, 50-year committed doses are calculated in accordance with the recommendations of the ICRP Publications 26 and 30, which were adopted by the US Department of Energy (DOE) in 1985. This new system calculates dose equivalent (DE) to individual organs and effective dose equivalent (EDE). The EDE is a risk-weighted DE that is designed to be an indicator of the potential health effects arising from the radiation dose. 16 refs., 1 fig., 38 tabs

  3. Proximal translation of > 1 mm within the first two years of revision total hip arthroplasty correctly predicts whether or not an acetabular component is loose in 80% of cases: a case-control study with confirmed intra-operative outcomes.

    Science.gov (United States)

    Kim, Y S; Abrahams, J M; Callary, S A; De Ieso, C; Costi, K; Howie, D W; Solomon, L B

    2017-04-01

    The purpose of this study was to determine the sensitivity, specificity and predictive values of previously reported thresholds of proximal translation and sagittal rotation of cementless acetabular components used for revision total hip arthroplasty (THA) at various times during early follow-up. Migration of cementless acetabular components was measured retrospectively in 84 patients (94 components) using Ein-Bild-Rontgen-Analyse (EBRA-Cup) in two groups of patients. In Group A, components were recorded as not being loose intra-operatively at re-revision THA (52 components/48 patients) and Group B components were recorded to be loose at re-revision (42 components/36 patients). The mean proximal translation and sagittal rotation were significantly higher in Group B than in Group A from three months onwards (p 1.0 mm within 24 months had a positive predictive value (PPV) of 90% and a specificity of 94%, but a sensitivity of 64%. Proximal translation > 1.0 mm within the first 24 months correctly identified 76 of 94 (81%) of components to be either loose or not loose. However, ten components in Group B (24%) did not migrate proximally above 1.0 mm within the first 60 months. The high PPV of EBRA-Cup measurements of proximal translation (90%) shows that this can be used in early follow-up to identify patients at risk of aseptic loosening. The absence of proximal translation within the first 60 months indicates a component is not likely to be loose at re-revision THA although it does not exclude late aseptic loosening as a cause of failure. Cite this article: Bone Joint J 2017;99-B:465-74. ©2017 The British Editorial Society of Bone & Joint Surgery.

  4. Characterization of ionizing radiation effects in MOS structures by study of bipolar operation

    International Nuclear Information System (INIS)

    Bakhtiar, H.; Picard, C.; Brisset, C.; Bakhtiar, H.; Hoffmann, A.; Charles, J.P.

    1999-01-01

    This work presents an original method to characterize radiation effects of micronic transistors. The characterization includes a study of the transistor substrate-drain junction and current gain variation of the bipolar transistor (drain-substrate-source as emitter-base-collector) for different gate voltages. (authors)

  5. Surface radiation survey and soil sampling of the 300-FF-1 operable unit, Hanford Site, southeastern Washington: A case study

    International Nuclear Information System (INIS)

    Teel, S.S.; Olsen, K.B.

    1990-10-01

    The methods used for conducting a radiological characterization of the soil surface for the Phase I Remedial Investigation of a Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) site is presented via a case study. The study site is an operable unit (300-FF-1) located in and adjacent to the 300 Area of the US Department of Energy's Hanford Site in southeastern Washington State. The operable unit contains liquid and solid waste disposal facilities associated with nuclear fuels fabrication. Continuous surface radiation surveying and soil sampling of selected locations were conducted. Contamination was found in several locations within the operable unit including areas near the liquid and solid waste disposal facilities. Instruments used during surveying included portable beta/gamma (P-11) detectors, and the Ultrasonic Ranging and Data System using an NaI (Tl) detector. Laboratory analyses results indicate that above-background radiation levels were primarily due to the presence of uranium. Both types of field instruments used in the study were effective in detecting surface contamination from radionuclides; however, each had specific advantages. Guidelines are presented for the optimum use of these instruments when performing a radiological characterization of the soil surface. 4 refs., 3 figs., 3 tabs

  6. Operational accidents and radiation exposures at DOE facilities. Fiscal year 1978

    International Nuclear Information System (INIS)

    1978-01-01

    Comprehensive safety programs are maintained at DOE facilities in order to protect both personnel and property from accidents. To ensure compliance with safety standards and regulations and maximize effectiveness of the safety programs, an extensive inspection and appraisal program is conducted at the contractor and field office levels by both DOE field and Headquarters safety personnel. When accidents do occur, investigations are conducted to identify causes and determine managerial or safety actions needed to prevent similar occurrences. DOE safety requirements include the reporting of personnel injury, property and motor vehicle losses on a quarterly basis, and radiation doses on an annual basis. The radiation dose data for CY 1978 are presented and reviewed in this report. All other data in this report are for FY 1978

  7. Radiation Dose Assessments for the Embryo, Fetus, and Nursing Infant during Operation Tomodachi

    Science.gov (United States)

    2013-08-01

    Health Affairs, who provided enthusiastic support and critical guidance. viii This page intentionally left blank. 1 Executive Summary The...rates, ingestion rates, and time spent outdoors (See Appendix C for the values used.) were used to calculate the doses in this report. Because high...account for exposure while performing at various levels of physical activity, whether indoors or outdoors . Environmental radiation data collected by the

  8. Evaluation of Radiation Exposure Hazard from Squaw Targets Used in Operations WIGWAM and HARDTACK-1

    Science.gov (United States)

    2016-07-01

    atmospheric nuclear testing in 1955 and 1958. The Squaw does not present a radiological hazard because neither of the two contamination pathways discussed in...possibility of radiological contamination of the third Squaw during its use in nuclear testing and the potential for a radiation exposure hazard are...3 joule (J) foot-pound-force (ft lbf) 1.355 818 joule (J) calorie (cal) (thermochemical) 4.184 joule (J) Pressure atmosphere (atm) 1.013 250

  9. Evaluation of Radiation Exposure Hazard from Squaw Targets Used in Operations WIGWAM and HARDTACK-I

    Science.gov (United States)

    2016-07-01

    atmospheric nuclear testing in 1955 and 1958. The Squaw does not present a radiological hazard because neither of the two contamination pathways discussed in...possibility of radiological contamination of the third Squaw during its use in nuclear testing and the potential for a radiation exposure hazard are...3 joule (J) foot-pound-force (ft lbf) 1.355 818 joule (J) calorie (cal) (thermochemical) 4.184 joule (J) Pressure atmosphere (atm) 1.013 250

  10. Some radiation safety aspects of operating medical generators of VHF electromagnetic energy

    International Nuclear Information System (INIS)

    Bosevski, V.; Radev, S.; Donev, Ch.

    1977-01-01

    The state of radiation safety in physiotherapy practice using very-high-frequency diathermy was studied with regard to personnel and patient protection. A specially devised shielding set to protect patients and personnel is offered for adoption, and the necessity is insistently stressed of prohibiting any patient head or gonad exposure. It is pointed out that the protective set developed may also be used at facilities employing other types of VHF electromagnetic energy sources. (author)

  11. Analysis of the numerical results of the melting paraffin corks, ensuring the safe operation of the pipeline using a mobile source of electromagnetic radiation

    Directory of Open Access Journals (Sweden)

    Titarenko Vera

    2017-01-01

    Full Text Available For the safe operation of the pipeline, ensuring its smooth operation was conducted analysis of the results of numerical simulation of melting of paraffin jams with using a mobile source of electromagnetic radiation. Carried out varying different parameters of the radiation source, the peculiarities of its movement, the nature of the change of geometry of the boundary of melting of paraffin plugs under different external conditions

  12. Measurement of new operational quantities with radiation protection instruments designed for working area monitoring and for individual monitoring

    International Nuclear Information System (INIS)

    Prigent, R.; Chary, J.; Chemtob, M.

    1992-01-01

    The ICRP recommended a dose limitation system based on numerical evaluation of the dose equivalent to organs or tissues, H T , which are used to calculate the effective dose, H E , by weighting. The ICRU proposed new operational quantities accessible to measurement which are conservative with respect to these recommendations. The objective of this paper is to recall briefly the basic recommendations and to find out if radiation protection instruments presently used calibrated in terms of the previous quantities are capable to measure these new quantities. A dozen of practical cases are presented. (author)

  13. Radiation Hardened High Speed Integrated Circuits SERDES I/O for Extreme Operating Environments, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Manned and robotic space missions require high-performance electronic control systems capable of operating for extended periods in harsh environments subject to...

  14. High Intensity Radiated Field External Environments for Civil Aircraft Operating in the United States of America

    National Research Council Canada - National Science Library

    Heather, Frederick

    2002-01-01

    ... (FAR) Parts 23, 25, 27, and 29. The HIRF survey determined the Rotorcraft Severe, Fixed Wing Severe, Certification, and Normal Environments that civil aircraft may be exposed to while operating in the continental U.S...

  15. High Intensity Radiated Field External Environments for Civil Aircraft Operating in the United States of America

    National Research Council Canada - National Science Library

    Heather, Frederick

    1998-01-01

    ...) Parts 23, 25, 27, and 29. The HIRF survey determined the Rotorcraft Severe, Fixed Wing Severe, Certification, and Normal Environments that civil aircraft may be exposed to while operating in the continental U.S...

  16. Higher operation temperature quadrant photon detectors of 2-11 μm wavelength radiation with large photosensitive areas

    Science.gov (United States)

    Pawluczyk, J.; Sosna, A.; Wojnowski, D.; Koźniewski, A.; Romanis, M.; Gawron, W.; Piotrowski, J.

    2017-10-01

    We report on the quadrant photon HgCdTe detectors optimized for 2-11 μm wavelength spectral range and Peltier or no cooling, and photosensitive area of a quad-cell of 1×1 to 4×4 mm. The devices are fabricated as photoconductors or multiple photovoltaic cells connected in series (PVM). The former are characterized by a relatively uniform photosensitive area. The PVM photovoltaic cells are distributed along the wafer surface, comprising a periodical stripe structure with a period of 20 μm. Within each period, there is an insensitive gap/trench 1.4×108 cm×Hz1/2/W for photoconductor and >1.7×108 cm·Hz1/2/W for PVM, allowing for position control of the radiation beam with submicron accuracy at 16 MHz, 10.6 μm wavelength of pulsed radiation spot of 0.8 mm dia at the close-to-maximal input radiation power density in a range of detector linear operation.

  17. Cost-benefit analysis of establishing and operating radiation oncology services in Fiji.

    Science.gov (United States)

    Kim, Eunkyoung; Cho, Yoon-Min; Kwon, Soonman; Park, Kunhee

    2017-10-01

    Rising demand for services of cancer patients has been recognised by the Government of Fiji as a national health priority. Increasing attention has been paid to the lack of service of radiation therapy or radiotherapy in Fiji. This study aims to estimate and compare the costs and benefits of introducing radiation oncology services in Fiji from the societal perspective. Time horizon for cost-benefit analysis (CBA) was 15 years from 2021 to 2035. The benefits and costs were converted to the present values of 2016. Estimates for the CBA model were taken from previous studies and expert opinions and data obtained from field visits to Fiji in January 2016. Sensitivity analyses with changing assumptions were undertaken. The estimated net benefit, applying the national minimum wage (NMW) to measure monetary value for life-year gained, was -31,624,421 FJD with 0.69 of benefit-cost (B/C) ratio. If gross national income (GNI) per capita was used for the value of life years, net benefit was 3,975,684 FJD (B/C ratio: 1.04). With a pessimistic scenario, establishing the center appeared to be not cost-beneficial, and the net benefit was -53,634,682 FJD (B/C ratio: 0.46); net benefit with an optimistic scenario was estimated 23,178,189 FJD (B/C ratio: 1.20). Based on the CBA results from using GNI per capita instead of the NMW, this project would be cost-beneficial. Introducing a radiation oncology center in Fiji would have potential impacts on financial sustainability, financial protection, and accessibility and equity of the health system. Copyright © 2017 World Health Organization. Published by Elsevier Ltd.. All rights reserved.

  18. Effective optimization of medical exposure: co-operation between radiation users and authorities

    International Nuclear Information System (INIS)

    Parkkinen, R.; Jarvinen, H.

    2006-01-01

    For the optimization of medical exposure in special radiological practices like in paediatric radiology, orthopaedics and cardiology, the Radiation and Nuclear Safety Authority (S.T.U.K.) in Finland has used a six step model to achieve the aims of the Medical Exposure Directive (97/43/EURATOM). The basis is to introduce the regulation and to meet the needs of the users for education and training. The aim is to educate some specialists to distribute information and good practices among their own professional groups. S.T.U.K. makes continuous verification on site visits and improves the process. (authors)

  19. O7.10CORRELATION OF PRE-OPERATIVE LANGUAGE FMRI WITH INTRA-OPERATIVE DIRECT CORTICAL STIMULATION FINDINGS IN GLIOMA SURGERY IDENTIFIES POTENTIAL FALSE POSITIVE FMRI ACTIVATIONS WITH CONVENTIONAL ANALYSIS

    Science.gov (United States)

    Coope, D.J.; Karabatsou, K.; Green, S.; Wall, G.; Bambrough, J.

    2014-01-01

    BACKGROUND: Functional MRI (fMRI) has an increasingly established role in surgical planning for glioma patients. However, the presence of neuro-vascular decoupling in the vicinity of the tumor, along with other tumor specific phenomena, raises at least theoretical concerns of potential inaccuracies. Several studies have attempted to correlate fMRI findings with cortical mapping performed using direct cortical stimulation (DCS). Results with respect to language mapping in particular have not been consistent and have focused upon investigating the sensitivity of fMRI to detect eloquent tissue. The possibility of false positive activations that could lead to regions of tumor being incorrectly labeled as inoperable has not been fully explored, in part due to the challenge of accurately recording DCS findings. METHODS: Ten patients with suspected primary or recurrent low-grade gliomas underwent pre-operative fMRI including 3-4 language paradigms on a Phillips 3T Achieva scanner. Comprehensive neuropsychological assessment was also completed prior to awake craniotomy. fMRI data processed using Phillips proprietary IViewBOLD was made available using the BrainLab VectorVision neuro-navigation system for planning of the craniotomy. The surgeon was blinded to fMRI outcomes for the duration of cortical mapping to minimize bias. DCS was completed using a bipolar stimulator tracked continuously using the BrainLab system networked via the VVLink interface to a research system running 3D Slicer. DCS outcomes were recorded by the surgeon using a panel of footswitches to trigger a custom logging module. fMRI data was re-processed using Statistical Parametric Mapping (SPM) 8 to generate t-statistic maps with a simple threshold of 3 applied analogous to the standard clinical implementation. DCS outcomes within 10mm of a cluster of ≥10 voxels above the threshold were analyzed. RESULTS: A mean of 125.4 [range 64-178] unique DCS outcomes were recorded per subject with 60 [32

  20. New technology development for radiation dose measurement and evaluation based on the operational quantity

    International Nuclear Information System (INIS)

    Kim, Jang Lyul; Kim, B. H.; Lee, J. I.; Lim, K. S.; Song, M. Y.; Joo, G. S.; Kim, S. I.; Chang, I. S.

    2012-04-01

    · Development of optically stimulated luminescence (OSL) technique for multi-purpose radiation dosimetry - Development of a semi-automatic type OSL measurement system · Number of sample holders: 10 ea · Development of a built-in type reference radiation irradiation system using 50 kV-1 mA X-rays of the maximum dose rate of 230 mGy/s - Development of an automatic diameter control system and crystal growth system for making a new OSL material: LiMgF 3 : X, LiAlO 2 : C - Development of a procedure of retrospective accident dosimetry · Establishment of Practical Technology for Internal Dose Assessment - Development of the technology to the internal dose assessment for an injection of radionuclides and intercomparison on the evaluation results of the committed effective dose between the estimators of Korea · Construction of workplace monitoring technique by quantification of neutron fields - Preparation of the neutron spectra DB of various neutron fields and production of those dosimetric data: 29 kinds of neutron fields using a thermal neutron irradiator, a proton accelerator and a neutron generator - Neutron monitoring procedure at workplace using neutron fluence spectra

  1. [111In-DTPA]octreotide tumor uptake in GEPNET liver metastases after intra-arterial administration: An overview of preclinical and clinical observations and implications for tumor radiation dose after peptide radionuclide therapy

    NARCIS (Netherlands)

    S.E. Pool (Stefan); B.L. Kam (Boen); G.A. Koning (Gerben); M. Konijnenberg (Mark); T.L.M. ten Hagen (Timo); W.A.P. Breeman (Woulter); E.P. Krenning (Eric); M. de Jong (Marcel); C.H.J. van Eijck (Casper)

    2014-01-01

    textabstractAims: With the aim to improve peptide receptor radionuclide therapy effects in patients with gastroenteropancreatic neuroendocrine tumor (GEPNET) liver metastases we explored the effect of intra-arterial (IA) administration of [111In-DTPA]octreotide (111In-DTPAOC) on tumor uptake in an

  2. Radiation doses to members of the public from the Olympic Dam Operation

    International Nuclear Information System (INIS)

    Crouch, Philip; Green, Steve; Worby, Mike

    2005-01-01

    The Olympic Dam project is a large underground mine with associated processing plant and smelter, producing copper, uranium, gold, and silver, and is located at Roxby Downs in central South Australia. Results from the monitoring of airborne radionuclides have been reviewed to estimate the operational related doses to members of the public living at Olympic Dam village, approximately 4 km south of the edge of the operational area. The results indicate that the doses are very low, with a conservative upper bound on annual effective dose from radon decay products of approximately 20 μSv and approximately 3 μSv per annum from inhalation of radioactive dusts

  3. Hardened Flip-Flop Optimized for Subthreshold Operation Heavy Ion Characterization of a Radiation

    Directory of Open Access Journals (Sweden)

    Eric Bozeman

    2012-05-01

    Full Text Available A novel Single Event Upset (SEU tolerant flip-flop design is proposed, which is well suited for very-low power electronics that operate in subthreshold ( < Vt ≈ 500 mV. The proposed flip-flop along with a traditional (unprotected flip-flop, a Sense-Amplifier-based Rad-hard Flip-Flop (RSAFF and a Dual Interlocked storage Cell (DICE flip-flop were all fabricated in MIT Lincoln Lab’s XLP 0.15 μm fully-depleted SOI CMOS technology—a process optimized for subthreshold operation. At the Cyclotron Institute at Texas A&M University, all four cells were subjected to heavy ion characterization in which the circuits were dynamically updated with alternating data and then checked for SEUs at both subthreshold (450 mV and superthreshold (1.5 V levels. The proposed flip-flop never failed, while the traditional and DICE designs did demonstrate faulty behavior. Simulations were conducted with the XLP process and the proposed flip-flop provided an improved energy delay product relative to the other non-faulty rad-hard flip-flop at subthreshold voltage operation. According to the XLP models operating in subthreshold at 250 mV, performance was improved by 31% and energy consumption was reduced by 27%.

  4. The influence of radiative transfer on the turbulent flow inside solar absorbers operating with supercritical CO

    NARCIS (Netherlands)

    Pecnik, R.; Smit, S.H.H.J.; Patel, A.; Roekaerts, D.J.E.M.

    2016-01-01

    In this paper we investigate and compare two dierent solar receiver technologies for concentrated solar power plants operating with supercritical CO2. The rst receiver is based on conventional surface absorbers, while the second receiver is based on an innovative idea to use volumetric receivers

  5. Atmospheric Radiation Measurement Program Climate Research Facility Operations Quarterly Report July 1 – September 30, 2006

    Energy Technology Data Exchange (ETDEWEB)

    DL Sisterson

    2006-10-01

    Description. Individual raw data streams from instrumentation at the Atmospheric Radiation Measurement (ARM) Program Climate Research Facility (ACRF) fixed and mobile sites are collected and sent to the Data Management Facility (DMF) at Pacific Northwest National Laboratory (PNNL) for processing in near real time. Raw and processed data are then sent daily to the ACRF Archive, where they are made available to users. For each instrument, we calculate the ratio of the actual number of data records received daily at the Archive to the expected number of data records. The results are tabulated by (1) individual data stream, site, and month for the current year and (2) site and fiscal year dating back to 1998.

  6. Atmospheric Radiation Measurement Program Climate Research Facility Operations Quarterly Report April 1 – June 30, 2006

    Energy Technology Data Exchange (ETDEWEB)

    DL Sisterson

    2006-07-01

    Description. Individual raw data streams from instrumentation at the Atmospheric Radiation Measurement (ARM) Program Climate Research Facility (ACRF) fixed and mobile sites are collected and sent to the Data Management Facility (DMF) at Pacific Northwest National Laboratory (PNNL) for processing in near real time. Raw and processed data are then sent daily to the ACRF Archive, where they are made available to users. For each instrument, we calculate the ratio of the actual number of data records received daily at the Archive to the expected number of data records. The results are tabulated by (1) individual data stream, site, and month for the current year; and (2) site and fiscal year dating back to 1998.

  7. Limitation of future radiation exposures from the present operation of nuclear fuel cycle installations

    International Nuclear Information System (INIS)

    Beninson, D.

    1982-01-01

    This paper reviews the bases and the formulation for limiting the doses in the future from the combined contribution of present and future practices causing radiation exposures. Local, regional and global contributions to the exposure of given population groups are discussed, and the use of the collective dose commitments for predicting future exposures from continuing practice is presented. The paper discusses the limitation of the dose commitment and of the collective dose commitment per unit practice as procedures for controlling future exposures. It also presents the bases used to assign upperbounds of exposure, which are fractions of the relevant dose limits, to exposures caused by a given source or practice. These considerations have been introduced in the regulatory requirements used in Argentina, and the paper examines the bases of the relevant provisions. (author)

  8. Operational Radiation Protection in veterinary centres; Proteccion Radiologica Operacional en centros veterinarios

    Energy Technology Data Exchange (ETDEWEB)

    Cordon, E.; Vigil, A.; Coll, A.

    2012-07-01

    Nowadays, there is a trend towards the use of digital radiography in the veterinary field. As a consequence, there could be a workload increase in the X-ray system and higher exposure for veterinarians and members of the public. In this study we analyze the influence of the X-ray machine output with with the radiation levels at the veterinarian position. We have considered the leads apron that each veterinarian center has and we have related its attenuation coefficient with the dose exposure at the veterinarian position. With the maximum workload, we have made a theoretical assessment for the primary barrier at 1 m of the X-ray focus.Despite there is a workload increase due to the digital technologies, the studied results show that is is very unlikely to be in excess of annual dose limit for the exposed workers. (Author) 5 refs.

  9. Operational accidents and radiation exposures at DOE facilities. Fiscal year 1979

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-12-01

    The Department of Energy's safety performance in fiscal year 1979 showed improvement in all categories over fiscal year 1978. The loss rates were less than one-half the United States industry average as reported by the National Safety Council. Incidence rates per 200,000 workhours were 1.1 lost workday cases and 17.2 lost workdays compared to 1.2 lost workday cases and 17.6 lost workdays during fiscal year 1978. The recordable occupational illness rate, based on only 80 cases, was 0.06 cases per 200,000 workhours compared to 0.07 cases per 200,000 workhours for fiscal year 1978. Nine fatalities of contractor employees resulted in an annual rate of 6.0 deaths per 100,000 workers compared with 10 fatalities during fiscal year 1978, and an annual rate of 6.7 deaths per 100,000 workers. The total Department of Energy property loss reported during fiscal year 1979 was $3.3 million; $765,400 was caused by fire, and $2.5 million by other causes. A total of 121 million vehicle miles of official travel resulted in 685 accidents with $338,400 in property damage. The loss rates of 5.7 accidents per million vehicle miles and $2.80 per 1000 miles were improvements over the fiscal year 1978 rates of 5.8 accidents per million vehicle miles and $2.97 property damage per 1000 miles. The 104,986 monitored Department of Energy and its contractor employees received a total dose of 9040 rem in calendar year 1979. Both the total dose and the 1748 employees receiving radiation exposures greater than 1 rem in 1979 represent a continuing downward trend from the calendar year 1978 total dose of 9380 rem and the 1826 employees who received radiation exposures greater than 1 rem.

  10. Operational accidents and radiation exposures at DOE facilities. Fiscal year 1979

    International Nuclear Information System (INIS)

    1980-12-01

    The Department of Energy's safety performance in fiscal year 1979 showed improvement in all categories over fiscal year 1978. The loss rates were less than one-half the United States industry average as reported by the National Safety Council. Incidence rates per 200,000 workhours were 1.1 lost workday cases and 17.2 lost workdays compared to 1.2 lost workday cases and 17.6 lost workdays during fiscal year 1978. The recordable occupational illness rate, based on only 80 cases, was 0.06 cases per 200,000 workhours compared to 0.07 cases per 200,000 workhours for fiscal year 1978. Nine fatalities of contractor employees resulted in an annual rate of 6.0 deaths per 100,000 workers compared with 10 fatalities during fiscal year 1978, and an annual rate of 6.7 deaths per 100,000 workers. The total Department of Energy property loss reported during fiscal year 1979 was $3.3 million; $765,400 was caused by fire, and $2.5 million by other causes. A total of 121 million vehicle miles of official travel resulted in 685 accidents with $338,400 in property damage. The loss rates of 5.7 accidents per million vehicle miles and $2.80 per 1000 miles were improvements over the fiscal year 1978 rates of 5.8 accidents per million vehicle miles and $2.97 property damage per 1000 miles. The 104,986 monitored Department of Energy and its contractor employees received a total dose of 9040 rem in calendar year 1979. Both the total dose and the 1748 employees receiving radiation exposures greater than 1 rem in 1979 represent a continuing downward trend from the calendar year 1978 total dose of 9380 rem and the 1826 employees who received radiation exposures greater than 1 rem

  11. Radiation protection aspects gained from the operation of FBTR. Basis for approach and criteria for future LMFBRs

    International Nuclear Information System (INIS)

    Meenakshisundaram, V.; Jose, M. T.

    2008-01-01

    Health Physics experience gained from the operation of Fast Breeder Test Reactor since more than twenty years is outlined. These include area monitoring, stack monitoring, annual discharge of activity released vis-a-vis technical specification limits, personnel monitoring that include man-rem expenditure, waste disposal etc. Basic aspects of Radiation and Air Activity Monitoring System (RAAMS), meant to monitor and record the radiation and air activity levels at various controlled areas in FBTR complex are given. Installation, calibration and usefulness of special monitors, unique to LMFBRs, such as gas flow ion chambers in the Clad Rupture Detection (CRD) argon circuit for detection of gaseous fission products, fume activity monitors in the ventilation ducts to indicate sodium leak / fire, sodium aerosol detection monitors in the primary double envelop sampling line and gas activity monitors are highlighted. Radiologically significant incidents such as minor sodium leak in the primary purification system in 2002 and special operations are reported. The experience gained during successful handling, treatment, and disposal of active primary sodium and decontamination of active sodium bearing components following steam-nitrogen process is brought out. Towards controlling external exposures to occupational workers during maintenance work, the salient features of the study conducted to assess the deposition of radioactive corrosion and activation products and dose rates in the primary sodium pipelines and various components of FBTR, which are housed in B-cells, are highlighted. The environmental aspects of LMFBRs are also briefly outlined. The lessons learnt from the experience gained such as lowering of alarm limit for particulate activity monitors to enable detection of primary sodium leak within reactor containment building, identification of deposition of 54 Mn in the interiors of primary sodium lines as a major contributor to the external dose component, the

  12. IR radiation characteristics and operating range research for a quad-rotor unmanned aircraft vehicle.

    Science.gov (United States)

    Gong, Mali; Guo, Rui; He, Sifeng; Wang, Wei

    2016-11-01

    The security threats caused by multi-rotor unmanned aircraft vehicles (UAVs) are serious, especially in public places. To detect and control multi-rotor UAVs, knowledge of IR characteristics is necessary. The IR characteristics of a typical commercial quad-rotor UAV are investigated in this paper through thermal imaging with an IR camera. Combining the 3D geometry and IR images of the UAV, a 3D IR characteristics model is established so that the radiant power from different views can be obtained. An estimation of operating range to detect the UAV is calculated theoretically using signal-to-noise ratio as the criterion. Field experiments are implemented with an uncooled IR camera in an environment temperature of 12°C and a uniform background. For the front view, the operating range is about 150 m, which is close to the simulation result of 170 m.

  13. Regional long-term co-operation in the field of nuclear and radiation emergency preparedness

    International Nuclear Information System (INIS)

    Sladek, V.; Metke, E.; Janko, K.; Hohenberg, J. K.; Hofer, P.

    2004-01-01

    Emergency preparedness is generally covered by methodical and coordinative activities of the International Atomic Energy Agency (IAEA) in Member States of the IAEA and by the European Commission (EC) in EU Member and EU Accession Countries. However, the regional harmonisation of emergency arrangements is an important trend of emergency preparedness. The present paper gives a couple of illustrative examples for a regional co-operation in the field of emergency preparedness in Central Europe and an overview on international exercises in this region. The penultimate section contains an outlook on future activities regarding regional co-operation in Central Europe. The following topics have been suggested inter alia: the harmonisation of intervention criteria and countermeasures, co-ordination in the field of information of the public, comprehensive bi lateral and multilateral exercises, exchange of experts between the national nuclear emergency centres and inter-comparison calculations of the computer codes. (authors)

  14. An augmented audit program for assuring radiation safety during radiographic examination operations

    International Nuclear Information System (INIS)

    Jervey, R.A. Jr.; Papin, P.J.

    1993-01-01

    Auditing a gamma radiography program is required as part of the authorizing license. Checklists and cursory reviews are the typical approach to addressing program requirements. A more proactive approach is recommended. The audit program described was prepared for a specific set of operating conditions but can be applied to any given program. Improvements in the effectiveness of the radiography safety program can be made with additional examination and emphasis on direct observation of licensed activities

  15. Surgical treatment of radiation enteritis

    Energy Technology Data Exchange (ETDEWEB)

    Cross, M.J.; Frazee, R.C. (Department of General Surgery, Scott and White Memorial Hospital, Temple TX (United States))

    1992-02-01

    Radiation enteritis is a progressive, disease process that causes intestinal fibrosis and obliterative endarteritis, which results in significant morbidity and mortality. The authors' clinical experience involving 20 patients over a 22-year period from 1967 through 1989 who underwent various surgical procedures to alleviate chronic symptoms secondary to radiation enteritis is described. Eight men and 12 women with a mean age of 52 years (24 to 81 years) underwent a total of 27 procedures for complications of radiation enteritis. Radiation therapy was delivered for treatment of gynecologic malignancies (55%), colorectal cancer (20%), prostate malignancies (10%), and others (15%). The mean average dose of radiation delivered was 5,514 rads with a range of 2,613 to 7,000 rads. The interval from radiation treatment to time of surgery averaged 9 years. Operative procedures consisted of 12 resection and primary anastomosis procedures and 15 resections with stoma creation. Formation of a stoma was used in patients with more severe disease. The 30-day operative mortality was 0% and morbidity was 55%. There were no anastomotic leaks or intra-abdominal abscesses. The authors conclude that resection and primary anastomosis can safely be performed in selected patients but that judicious use of stoma formation can avoid major mortality and morbidity associated with surgery in this setting.

  16. Surgical treatment of radiation enteritis

    International Nuclear Information System (INIS)

    Cross, M.J.; Frazee, R.C.

    1992-01-01

    Radiation enteritis is a progressive, disease process that causes intestinal fibrosis and obliterative endarteritis, which results in significant morbidity and mortality. The authors' clinical experience involving 20 patients over a 22-year period from 1967 through 1989 who underwent various surgical procedures to alleviate chronic symptoms secondary to radiation enteritis is described. Eight men and 12 women with a mean age of 52 years (24 to 81 years) underwent a total of 27 procedures for complications of radiation enteritis. Radiation therapy was delivered for treatment of gynecologic malignancies (55%), colorectal cancer (20%), prostate malignancies (10%), and others (15%). The mean average dose of radiation delivered was 5,514 rads with a range of 2,613 to 7,000 rads. The interval from radiation treatment to time of surgery averaged 9 years. Operative procedures consisted of 12 resection and primary anastomosis procedures and 15 resections with stoma creation. Formation of a stoma was used in patients with more severe disease. The 30-day operative mortality was 0% and morbidity was 55%. There were no anastomotic leaks or intra-abdominal abscesses. The authors conclude that resection and primary anastomosis can safely be performed in selected patients but that judicious use of stoma formation can avoid major mortality and morbidity associated with surgery in this setting

  17. Operation of the Nuclear Radiation Center as an all-university facility

    International Nuclear Information System (INIS)

    Hinman, G.W.

    1972-01-01

    The TRIGA at WSU is part of an all university research unit and its structure and work organization are presented. The facility seeks users from the university and from outside the university. In many cases projects are jointly sponsored by NRC faculty together with faculty from elsewhere on campus. In other cases neutrons or free use of other equipment is provided. The promotional efforts are rather sharply focused on environmental and health related problems. The effects of the institutional arrangement on the operation of the Centre are discussed

  18. A comparison study of radiation exposure to patients during EVAR and Dyna CT in an angiosuite vs. an operating theatre.

    Science.gov (United States)

    Bruschi, Andrea; Michelagnoli, Stefano; Chisci, Emiliano; Mazzocchi, Silvia; Panci, Simone; Didona, Annamaria; Ghirelli, Alessandro; Zatelli, Giovanna

    2015-03-01

    The aim of this study was to assess the patient dosimetric impact of endovascular abdominal aortic aneurysm repair (EVAR), both in an operating theatre (OR) and in an angiosuite (AS), with the facility of Dynamic CT (Dyna CT, Siemens AG, Berlin, Germany). One hundred and forty-six consecutive EVAR procedures dating from May 2011 to March 2013 were analysed. These were performed either in an OR (n = 97) using a mobile C-arm or in an AS (n = 49) equipped with a ceiling-mounted angiography system. Air kerma area product (P(KA)) and total air kerma at reference point (K(a,r)) values were reported for all procedures and Dyna CT. Radiation exposure during EVAR was quite low in the majority of patients but nearly 50 % higher if performed in AS vs. OR. Median Dyna CT K(a,r) was the same as an entire EVAR procedure in OR. The higher patient's radiation exposure recorded in the AS should be balanced with the technical advantages given to the EVAR procedure. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  19. Radiation-epidemiological Study of Cerebrovascular Diseases in the Cohort of Russian Recovery Operation Workers of the Chernobyl Accident.

    Science.gov (United States)

    Kashcheev, V V; Chekin, S Yu; Maksioutov, M A; Tumanov, K A; Menyaylo, A N; Kochergina, E V; Kashcheeva, P V; Gorsky, A I; Shchukina, N V; Karpenko, S V; Ivanov, V K

    2016-08-01

    The paper presents an analysis of the incidence of cerebrovascular diseases (CeVD) in the cohort of Russian workers involved in recovery tasks after the Chernobyl accident. The studied cohort consists of 53,772 recovery operation workers (liquidators) who arrived in the zone of the Chernobyl accident within the first year after this accident (26 April 1986-26 April 1987). The mean external whole body dose in the cohort was 0.161 Gy, while individual doses varied from 0.0001 Gy to 1.42 Gy. During the follow-up period 1986-2012, a total of 23,264 cases of CeVD were diagnosed as a result of annual health examinations. A Poisson regression model was applied for estimation of radiation risks and for an assessment of other risk factors of CeVD. The following factors were considered as risk factors for CeVD: the dose, duration of the liquidators' work in the Chernobyl zone, and the concomitant diseases (hypertension, ischemic heart disease, atherosclerosis, and diabetes). The baseline incidence of CeVD is statistically significantly (p Chernobyl zone; for those who stayed in the Chernobyl zone less than 6 wk, ERR/Gy = 0.64, 95% CI = (0.38; 0.93), p < 0.001. Among studied concomitant diseases, diabetes mellitus statistically significantly (p = 0.002) increases the radiation risk of CeVD: for liquidators with diagnosed diabetes, ERR/Gy = 1.29.

  20. Coherent Synchrotron Radiation A Simulation Code Based on the Non-Linear Extension of the Operator Splitting Method

    CERN Document Server

    Dattoli, Giuseppe

    2005-01-01

    The coherent synchrotron radiation (CSR) is one of the main problems limiting the performance of high intensity electron accelerators. A code devoted to the analysis of this type of problems should be fast and reliable: conditions that are usually hardly achieved at the same time. In the past, codes based on Lie algebraic techniques have been very efficient to treat transport problem in accelerators. The extension of these method to the non-linear case is ideally suited to treat CSR instability problems. We report on the development of a numerical code, based on the solution of the Vlasov equation, with the inclusion of non-linear contribution due to wake field effects. The proposed solution method exploits an algebraic technique, using exponential operators implemented numerically in C++. We show that the integration procedure is capable of reproducing the onset of an instability and effects associated with bunching mechanisms leading to the growth of the instability itself. In addition, parametric studies a...

  1. Proton Radiation Therapy in the Hospital Environment: Conception, Development, and Operation of the Initial Hospital-Based Facility

    Science.gov (United States)

    Slater, James M.; Slater, Jerry D.; Wroe, Andrew J.

    The world's first hospital-based proton treatment center opened at Loma Linda University Medical Center in 1990, following two decades of development. Patients' needs were the driving force behind its conception, development, and execution; the primary needs were delivery of effective conformal doses of ionizing radiation and avoidance of normal tissue to the maximum extent possible. The facility includes a proton synchrotron and delivery system developed in collaboration with physicists and engineers at Fermi National Accelerator Laboratory and from other high-energy-physics laboratories worldwide. The system, operated and maintained by Loma Linda personnel, was designed to be safe, reliable, flexible in utilization, efficient in use, and upgradeable to meet demands of changing patient needs and advances in technology. Since the facility opened, nearly 14,000 adults and children have been treated for a wide range of cancers and other diseases. Ongoing research is expanding the applications of proton therapy, while reducing costs.

  2. Didactic revision of the operative magnitudes system ICRU for the evaluation of the equivalent dose in radiation external fields

    International Nuclear Information System (INIS)

    Alvarez R, J. T.

    2014-10-01

    In this work is presented in a didactic way the operative magnitudes system ICRU, showing as these magnitudes carry out an appropriate estimate of the effective equivalent doses H E and the effective dose. The objective is to present the basic concepts of the dosimetry for radiation external fields with purposes of radiological protection, because the assimilation lack and technological development of this dosimetric magnitudes system has persisted for near 50 years, in terms of practice of the radiological protection in Mexico. Also, this system is an essential part of safety basic standards of the IAEA and ICRP recommendations 26, 60, 74 and 103, as well as of the ICRU 25, 39, 43, 51 and 57. (Author)

  3. Tatooing of tumor borders in cancer of the oral cavity oropharynx as a guide for orientation in radical operation after radiation

    International Nuclear Information System (INIS)

    Steinert, R.; Sesterhenn, K.; Rose, K.G.

    1982-01-01

    To improve the local rate of success or the conversion of cancers of the cavum oris and of the oropharynx which are inoperable because of their local situation, preoperative radiation is carried out in cases where this is appropriate. The radiation and the radical operation must be coordinated with each other. For this purpose the borders of the cancer are marked by tatooing them with ink. The tatooing makes it possible both to judge the effects of the radiation accurately and to locate the borders of the tumor with the naked eye after radiation treatment in apparently healthy tissues. In this way it is possible to perform the radical operation with an adequate safety margin around the pre-therapeutic borders of the tumor. With this method the rate of success in tongue-body, tongue-ground and tonsil cancers can be improved. (orig.) [de

  4. Operational accidents and radiation exposures at ERDA facilities, 1975-1977

    Energy Technology Data Exchange (ETDEWEB)

    1980-05-01

    The Energy Research and Development Administration (ERDA) accident frequency and losses were similar to that of the Atomic Energy Commission (AEC) from 1970 through 1974. The ERDA incidence rates per 200,000 work hours were 1.05 for lost workday injuries and 17.8 for workdays lost. These rates are about one-third of the national industrial averages reported by the National Safety Council (NSC). Ten fatalities occurred at ERDA facilities resulting in an average annual rate of three deaths per 100,000 workers compared to the national rate of 14 deaths per 100,000 workers. ERDA's total property loss from 1975 to 1977 was $11.9 million; $1.8 million caused by fires. The average annual loss rates, in cents loss per $100 valuation, were 1.15 for non-fire and 0.18 for fire. These rates are higher than the AEC post; Rocky Flats period (1970 through 1974) which were 0.60 non-fire and 0.10 fire; but are lower than the average annual rates which were 2.4 non-fire and 1.7 fire for the entire history of the AEC. Accidents causing more than $50,000 in property damage are tabulated. ERDA continued to make a strong effort to eliminate unnecessary radiation exposure to workers. The number of employees exceeding 1 rem decreased from 2999 in 1975 to 2274 in 1977. The two appendixes include criteria for accident investigations and summaries of accident investigation reports.

  5. Operational accidents and radiation exposures at ERDA facilities, 1975-1977

    International Nuclear Information System (INIS)

    1980-05-01

    The Energy Research and Development Administration (ERDA) accident frequency and losses were similar to that of the Atomic Energy Commission (AEC) from 1970 through 1974. The ERDA incidence rates per 200,000 work hours were 1.05 for lost workday injuries and 17.8 for workdays lost. These rates are about one-third of the national industrial averages reported by the National Safety Council (NSC). Ten fatalities occurred at ERDA facilities resulting in an average annual rate of three deaths per 100,000 workers compared to the national rate of 14 deaths per 100,000 workers. ERDA's total property loss from 1975 to 1977 was $11.9 million; $1.8 million caused by fires. The average annual loss rates, in cents loss per $100 valuation, were 1.15 for non-fire and 0.18 for fire. These rates are higher than the AEC post; Rocky Flats period (1970 through 1974) which were 0.60 non-fire and 0.10 fire; but are lower than the average annual rates which were 2.4 non-fire and 1.7 fire for the entire history of the AEC. Accidents causing more than $50,000 in property damage are tabulated. ERDA continued to make a strong effort to eliminate unnecessary radiation exposure to workers. The number of employees exceeding 1 rem decreased from 2999 in 1975 to 2274 in 1977. The two appendixes include criteria for accident investigations and summaries of accident investigation reports

  6. Strengthening the Radiation Protection System in Cuba (SRPS - Cuba). A co-operation project between Cuban and Swedish institutions, February 2001 - June 2003

    International Nuclear Information System (INIS)

    Avila, Rodolfo; Larsson, Carl-Magnus; Prendes, Miguel; Zerquera, Juan Tomas

    2004-02-01

    This project results from the co-operation between a number of Cuban and Swedish institutions. It started in February 2001 and ended in June 2003 and was made possible thanks to the contributions of the Swedish International Development Co-operation Agency (SIDA), the Centro de Proteccion e Higiene de las Radiaciones, Cuba (CPHR), and the Swedish Radiation Protection Authority (SSI). The overall objective was to strengthen the radiation protection system in Cuba, and in this way contribute with the control and reduction of risks to man and the environment from exposures to ionizing radiation. The project focused on four priority areas: 1) Protection of workers and patients exposed to radiation in radiation practices; 2) Preparedness for response to an emergency situation; 3) Environmental radiological protection; and, 4) Exposure to radiation in areas with high levels of natural radioactivity. The present report summarizes the findings of the whole project period, providing an overview of the overall achievements, as well as listing its deliverables. The results of an evaluation of the project, conducted during the final workshop, are also included. The report ends with a list of generic and specific conclusions and recommendations for implementation of the project's achievements and for further development of co-operation

  7. Strengthening the Radiation Protection System in Cuba (SRPS - Cuba). A co-operation project between Cuban and Swedish institutions, February 2001 - June 2003

    Energy Technology Data Exchange (ETDEWEB)

    Avila, Rodolfo; Larsson, Carl-Magnus; Prendes, Miguel; Zerquera, Juan Tomas

    2004-02-01

    This project results from the co-operation between a number of Cuban and Swedish institutions. It started in February 2001 and ended in June 2003 and was made possible thanks to the contributions of the Swedish International Development Co-operation Agency (SIDA), the Centro de Proteccion e Higiene de las Radiaciones, Cuba (CPHR), and the Swedish Radiation Protection Authority (SSI). The overall objective was to strengthen the radiation protection system in Cuba, and in this way contribute with the control and reduction of risks to man and the environment from exposures to ionizing radiation. The project focused on four priority areas: 1) Protection of workers and patients exposed to radiation in radiation practices; 2) Preparedness for response to an emergency situation; 3) Environmental radiological protection; and, 4) Exposure to radiation in areas with high levels of natural radioactivity. The present report summarizes the findings of the whole project period, providing an overview of the overall achievements, as well as listing its deliverables. The results of an evaluation of the project, conducted during the final workshop, are also included. The report ends with a list of generic and specific conclusions and recommendations for implementation of the project's achievements and for further development of co-operation.

  8. After-operating properties of nuclear reactor vessel materials of Lenin atomic ice breaker and prospective of reactor vessels radiation life prolongation

    International Nuclear Information System (INIS)

    Platonov, P.A.; Shtrombakh, Ya.I.; Amaev, A.D.; Krasikov, E.A.; Korolev, Yu.N.; Zabusov, O.O.; Glushakov, G.M.

    2001-01-01

    A post-operational state of the icebreaker Lenin reactor vessel metal is investigated. It is shown that a base metal of the icebreaker Lenin reactor vessel is of high quality as by an initial value of critical temperature of embrittlement, so by its radiation resistance. The weld metal possesses a sufficient radiation resistance but has an insufficient initial ductile-brittle transition temperature (approximately 63 Deg C). It is necessary to note that the final stage of operation for nuclear steam-generating plant should be carried out at the coolant temperature as high as possible [ru

  9. Enabling Wireless Avionics Intra-Communications

    Science.gov (United States)

    Torres, Omar; Nguyen, Truong; Mackenzie, Anne

    2016-01-01

    The Electromagnetics and Sensors Branch of NASA Langley Research Center (LaRC) is investigating the potential of an all-wireless aircraft as part of the ECON (Efficient Reconfigurable Cockpit Design and Fleet Operations using Software Intensive, Networked and Wireless Enabled Architecture) seedling proposal, which is funded by the Convergent Aeronautics Solutions (CAS) project, Transformative Aeronautics Concepts (TAC) program, and NASA Aeronautics Research Institute (NARI). The project consists of a brief effort carried out by a small team in the Electromagnetic Environment Effects (E3) laboratory with the intention of exposing some of the challenges faced by a wireless communication system inside the reflective cavity of an aircraft and to explore potential solutions that take advantage of that environment for constructive gain. The research effort was named EWAIC for "Enabling Wireless Aircraft Intra-communications." The E3 laboratory is a research facility that includes three electromagnetic reverberation chambers and equipment that allow testing and generation of test data for the investigation of wireless systems in reflective environments. Using these chambers, the EWAIC team developed a set of tests and setups that allow the intentional variation of intensity of a multipath field to reproduce the environment of the various bays and cabins of large transport aircraft. This setup, in essence, simulates an aircraft environment that allows the investigation and testing of wireless communication protocols that can effectively be used as a tool to mitigate some of the risks inherent to an aircraft wireless system for critical functions. In addition, the EWAIC team initiated the development of a computational modeling tool to illustrate the propagation of EM waves inside the reflective cabins and bays of aircraft and to obtain quantifiable information regarding the degradation of signals in aircraft subassemblies. The nose landing gear of a UAV CAD model was used

  10. Evidence supporting contemporary post-operative radiation therapy (PORT) using linear accelerators in N2 lung cancer.

    Science.gov (United States)

    Patel, Suchit H; Ma, Yan; Wernicke, A Gabriella; Nori, Dattatreyudu; Chao, K S C; Parashar, Bhupesh

    2014-05-01

    Post-operative radiotherapy (PORT) treatment for lung cancer declined since a meta-analysis failed to show benefit in patients with N2 disease. Because several included studies employed outmoded radiation planning and delivery techniques, we sought to determine whether PORT with modern technology benefits patients with N2 disease. We conducted searches of the published literature. For inclusion, studies must have included patients with stage III-N2 lung cancer treated with PORT using only linear accelerators, used a control group that did not receive PORT, and reported outcome data for overall survival (OS). Prospective and retrospective analyses were included. Exclusion criteria were the use of cobalt devices or orthovoltage radiation. Data were evaluated with random-effects models. Three prospective and eight retrospective studies were included. The PORT and no-PORT groups included 1368 and 1360 patients, respectively. The PORT group had significantly improved OS over the no-PORT group (hazard ratio [HR] = 0.77, 95% confidence interval [CI] 0.62-0.96, P = 0.020). Locoregional recurrence-free survival (LRFS) in 10 studies for which data was available was also improved in the PORT group (HR = 0.51, CI 0.41-0.65, P PORT was associated with significantly lower risk of death and locoregional recurrence in patients with N2 lung cancer. Our study was limited by lack of access to individual patient data, which would have enabled more detailed analyses. Regardless, data thus far suggest PORT may be associated with a survival benefit. Given a lack of large-scale prospective data, clinical trials evaluating PORT with modern technology are warranted. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  11. A web-based remote radiation treatment planning system using the remote desktop function of a computer operating system: a preliminary report.

    Science.gov (United States)

    Suzuki, Keishiro; Hirasawa, Yukinori; Yaegashi, Yuji; Miyamoto, Hideki; Shirato, Hiroki

    2009-01-01

    We developed a web-based, remote radiation treatment planning system which allowed staff at an affiliated hospital to obtain support from a fully staffed central institution. Network security was based on a firewall and a virtual private network (VPN). Client computers were installed at a cancer centre, at a university hospital and at a staff home. We remotely operated the treatment planning computer using the Remote Desktop function built in to the Windows operating system. Except for the initial setup of the VPN router, no special knowledge was needed to operate the remote radiation treatment planning system. There was a time lag that seemed to depend on the volume of data traffic on the Internet, but it did not affect smooth operation. The initial cost and running cost of the system were reasonable.

  12. INTERACTION OF LASER RADIATION WITH MATTER: Influence of a target on operation of a pulsed CO2 laser emitting microsecond pulses

    Science.gov (United States)

    Baranov, V. Yu; Dolgov, V. A.; Malyuta, D. D.; Mezhevov, V. S.; Semak, V. V.

    1987-12-01

    The profile of pulses emitted by a TEA CO2 laser with an unstable resonator changed as a result of interaction of laser radiation with the surface of a metal in the presence of a breakdown plasma. This influence of a target on laser operation and its possible applications in laser processing of materials are analyzed.

  13. The efficacy of intra-articular bupivacaine for relief of pain following arthroscopy of the ankle.

    Science.gov (United States)

    Middleton, F; Coakes, J; Umarji, S; Palmer, S; Venn, R; Panayiotou, S

    2006-12-01

    The intra-articular injection of local anaesthetic is frequently used for pain relief after arthroscopy. There is, however, no published evidence of the analgesic effect of bupivacaine in the ankle. In a randomised, double-blind study, 35 patients undergoing arthroscopy of the ankle were allocated to receive intra-articular saline or bupivacaine. Pain was assessed using pain scores and additional analgesic requirements. Intra-articular bupivacaine had a significant analgesic effect in the immediate post-operative period, reducing pain scores and the need for additional analgesics. We recommend the use of intra-articular bupivacaine for post-operative analgesia in ankle surgery.

  14. Evaluation of Radiation Exposure during Construction and Operation of Concrete Bridge Reinforced with Very Low Level Radioactive Steel

    International Nuclear Information System (INIS)

    Panik, M.; Necas, V.

    2012-01-01

    A lot of nuclear power plants are approaching the end of their lifetime and they will be phased out. Decommissioning of these nuclear power plants involve complete dismantling of technologies and demolition of buildings. During this process it is produced plenty of waste material of different categories. Significant portion of decommissioning materials comprise radionuclides what is caused by contamination and activation processes mostly from the operational period of nuclear power plant. Attention in this paper is paid to waste steel from the decommissioning of nuclear power plants with the specific activity just slightly exceeding legislation limits for the unconditional release into the environment. From the traditional point of view this material should be treated, conditioned and disposed on the radioactive waste repository. Second possibility is to release this material conditionally and reuse it in chosen industrial application. Very low level radioactive steel scrap should be melted and melting products should be processed into products that can be applied in industry. First option requires considerable financial investment, human resources and repository capacity. Second option saves some financial funds and it enables to reuse and save potentially valuable material for the future. Paper comprises evaluation of external and internal exposure during construction and operation of concrete bridges that utilize very low level radioactive steel as part of their reinforcement. Two models of representative concrete bridges were created. External gamma exposure and exposure from inhalation and ingestion of radionuclides were calculated using suitable computational tools. VISIPLAN 3D ALARA planning tool was chosen for the calculation of external gamma exposure. Software GOLDSIM enables to calculate transport of radionuclides initially contained in conditionally released reinforcement steel through subsoil and sequential exposure of people caused by inhalation of

  15. Optimization of a Radiative Transfer Forward Operator for Simulating SMOS Brightness Temperatures over the Upper Mississippi Basin, USA

    Science.gov (United States)

    Lievens, H.; Verhoest, N. E. C.; Martens, B.; VanDenBerg, M. J.; Bitar, A. Al; Tomer, S. Kumar; Merlin, O.; Cabot, F.; Kerr, Y.; DeLannoy, G. J. M.; hide

    2014-01-01

    The Soil Moisture and Ocean Salinity (SMOS) satellite mission is routinely providing global multi-angular observations of brightness temperature (TB) at both horizontal and vertical polarization with a 3-day repeat period. The assimilation of such data into a land surface model (LSM) may improve the skill of operational flood forecasts through an improved estimation of soil moisture (SM). To accommodate for the direct assimilation of the SMOS TB data, the LSM needs to be coupled with a radiative transfer model (RTM), serving as a forward operator for the simulation of multi-angular and multi-polarization top of atmosphere TBs. This study investigates the use of the Variable Infiltration Capacity (VIC) LSM coupled with the Community Microwave Emission Modelling platform (CMEM) for simulating SMOS TB observations over the Upper Mississippi basin, USA. For a period of 2 years (2010-2011), a comparison between SMOS TBs and simulations with literature-based RTM parameters reveals a basin averaged bias of 30K. Therefore, time series of SMOS TB observations are used to investigate ways for mitigating these large biases. Specifically, the study demonstrates the impact of the LSM soil moisture climatology in the magnitude of TB biases. After CDF matching the SM climatology of the LSM to SMOS retrievals, the average bias decreases from 30K to less than 5K. Further improvements can be made through calibration of RTM parameters related to the modeling of surface roughness and vegetation. Consequently, it can be concluded that SM rescaling and RTM optimization are efficient means for mitigating biases and form a necessary preparatory step for data assimilation.

  16. Implications of Graphite Radiation Damage on the Neutronic, Operational, and Safety Aspects of Very High Temperature Reactors

    International Nuclear Information System (INIS)

    Hawari, Ayman I.

    2011-01-01

    In both the prismatic and pebble bed designs of Very High Temperature Reactors (VHTR), the graphite moderator is expected to reach exposure levels of 10 21 to 10 22 n/cm 2 over the lifetime of the reactor. This exposure results in damage to the graphite structure. In this work, molecular dynamic and ab initio molecular static calculations will be used to: (1) simulate radiation damage in graphite under various irradiation and temperature conditions, (2) generate the thermal neutron scattering cross sections for damaged graphite, and (3) examine the resulting microstructure to identify damage formations that may produce the high-temperature Wigner effect. The impact of damage on the neutronic, operational and safety behavior of the reactor will be assessed using reactor physics calculations. In addition, tests will be performed on irradiated graphite samples to search for the high-temperature Wigner effect, and phonon density of states measurements will be conducted to quantify the effect on thermal neutron scattering cross sections using these samples.

  17. Intra-individual diagnostic image quality and organ-specific-radiation dose comparison between spiral cCT with iterative image reconstruction and z-axis automated tube current modulation and sequential cCT

    International Nuclear Information System (INIS)

    Wenz, Holger; Maros, Máté E.; Meyer, Mathias; Gawlitza, Joshua; Förster, Alex; Haubenreisser, Holger; Kurth, Stefan; Schoenberg, Stefan O.; Groden, Christoph; Henzler, Thomas

    2016-01-01

    •Superiority of spiral versus sequential cCT in image quality and organ-specific-radiation dose.•Spiral cCT: lower organ-specific-radiation-dose in eye lense compared to tilted sequential cCT.•State-of-the-art IR spiral cCT techniques has significant advantages over sequential cCT techniques. Superiority of spiral versus sequential cCT in image quality and organ-specific-radiation dose. Spiral cCT: lower organ-specific-radiation-dose in eye lense compared to tilted sequential cCT. State-of-the-art IR spiral cCT techniques has significant advantages over sequential cCT techniques. To prospectively evaluate image quality and organ-specific-radiation dose of spiral cranial CT (cCT) combined with automated tube current modulation (ATCM) and iterative image reconstruction (IR) in comparison to sequential tilted cCT reconstructed with filtered back projection (FBP) without ATCM. 31 patients with a previous performed tilted non-contrast enhanced sequential cCT aquisition on a 4-slice CT system with only FBP reconstruction and no ATCM were prospectively enrolled in this study for a clinical indicated cCT scan. All spiral cCT examinations were performed on a 3rd generation dual-source CT system using ATCM in z-axis direction. Images were reconstructed using both, FBP and IR (level 1–5). A Monte-Carlo-simulation-based analysis was used to compare organ-specific-radiation dose. Subjective image quality for various anatomic structures was evaluated using a 4-point Likert-scale and objective image quality was evaluated by comparing signal-to-noise ratios (SNR). Spiral cCT led to a significantly lower (p < 0.05) organ-specific-radiation dose in all targets including eye lense. Subjective image quality of spiral cCT datasets with an IR reconstruction level 5 was rated significantly higher compared to the sequential cCT acquisitions (p < 0.0001). Consecutive mean SNR was significantly higher in all spiral datasets (FBP, IR 1–5) when compared to sequential cCT with a mean

  18. Intra- and interspecific differences of 10 barley and 10 tomato cultivars in response to short-time UV-B radiation: A study analysing thermoluminescence, fluorescence, gas-exchange and biochemical parameters

    International Nuclear Information System (INIS)

    Gilbert, Matthias; Poers, Yvonne; Grover, Kirsten; Weingart, Ilka; Skotnica, Jiri; Grimm, Bernhard; Seidlitz, Harald K.; Langebartels, Christian; Wilhelm, Christian

    2009-01-01

    The impact of UV-B radiation on 10 genotypically different barley and tomato cultivars was tested in a predictive study to screen for potentially UV-tolerant accessions and to analyze underlying mechanisms for UV-B sensitivity. Plant response was analyzed by measuring thermoluminescence, fluorescence, gas exchange and antioxidant status. Generally, barley cultivars proved to be much more sensitive against UV-B radiation than tomato cultivars. Statistical cluster analysis could resolve two barley groups with distinct differences in reaction patterns. The UV-B sensitive group showed a stronger loss in PSII photochemistry and a lower gas-exchange performance and regulation after UV-B radiation compared to the more tolerant group. The results indicate that photosynthetic light and dark reactions have to play optimally in concert to render plants more tolerant against UV-B radiation. Hence, measuring thermoluminescence/fluorescence and gas exchange in parallel will have much higher potential in identifying tolerant cultivars and will help to understand the underlying mechanisms. - Mechanisms of UV-B tolerance and sensitivity in crop plants.

  19. Laparoscopy and Intra-Abdominal Sepsis

    Directory of Open Access Journals (Sweden)

    Coyne

    2015-06-01

    Full Text Available Context Intra-abdominal sepsis has significant morbidity and mortality. In the developed world, there are many common causes originating from the lower gastrointestinal tract including diverticular disease, appendicitis, perforated cancers, and inflammatory bowel disease. It has a high cost and is associated with high levels of significant morbidity and mortality. Management options include radiologic drainage and surgical options include resection for more widespread sepsis. Laparoscopic surgery has increased and has been useful in elective setting. Its use in the emergency setting is less evaluated. Evidence Acquisition Evidence was acquired by searching online medical databases including Pubmed, Medline and Embase. Results Laparoscopic surgery has been shown to have a role in the acute setting. Studies show it has become the gold standard in the appendicitis. High quality Randomized controlled trials are in short supply but observational and cohort studies have shown equivalence and with increasing experience complication rates are reduced. Evidence is also increasing in the management of diverticular disease, crohn’s and ulcerative colitis as well as post-operative complication management and acute presentations of colorectal cancer. Conclusions Laparoscopic surgery is feasible in the management of intra-abdominal sepsis. It has become the new accepted standard in the management of appendicitis, and is safe, feasible and increasing in the management of complex diverticular disease, acute IBD and colorectal cancer in the emergency and post-operative setting.

  20. Image quality and radiation dose of coronary CT angiography performed with whole-heart coverage CT scanner with intra-cycle motion correction algorithm in patients with atrial fibrillation.

    Science.gov (United States)

    Andreini, Daniele; Pontone, Gianluca; Mushtaq, Saima; Mancini, Maria Elisabetta; Conte, Edoardo; Guglielmo, Marco; Volpato, Valentina; Annoni, Andrea; Baggiano, Andrea; Formenti, Alberto; Ditali, Valentina; Perchinunno, Marco; Fiorentini, Cesare; Bartorelli, Antonio L; Pepi, Mauro

    2018-04-01

    To evaluate image quality, coronary evaluability and radiation exposure of coronary CT angiography (CCTA) performed with whole-heart coverage cardiac-CT in patients with atrial fibrillation (AF). We prospectively enrolled 164 patients with AF who underwent a clinically indicated CCTA with a 16-cm z-axis coverage scanner. In all patients CCTA was performed using prospective ECG-triggering with targeted RR interval. We evaluated image quality, coronary evaluability and effective dose (ED). Patients were divided in two subgroups based on heart rate (HR) during imaging. Group 1: 64 patients with low HR (ethics committee approved the study protocol. In a segment-based analysis, coronary evaluability was 98.4 % (2,577/2,620 segments) in the whole population, without significant differences between groups (1,013/1,024 (98.9 %) and 1,565/1,596 (98.1 %), for groups 1 and 2, respectively, p=0.15). Mean ED was similar in both groups (3.8±1.9 mSv and 3.9±2.1 mSv in groups 1 and 2, respectively, p=0.75) CONCLUSIONS: The whole-heart-coverage scanner could evaluate coronary arteries with high image quality and without increase in radiation exposure in AF patients, even in the high HR group. • Last-generation CT scanner improves coronary artery assessment in AF patients. • The new CT scanner enables low radiation exposure in AF patients. • Diagnostic ICA maybe avoided in AF patients with suspected CAD. • Whole-heart coverage CT scanner enables low radiation exposure in AF patients.

  1. Range of the radiation monitor for the rigid vent of primary containment during normal and emergency operation for a BWR-5 in Laguna Verde

    International Nuclear Information System (INIS)

    Tijerina S, F.; Pozos S, A. M.; Cabrera U, S.; Mata A, J. A.; Sandoval V, S.; Ovando C, R.; Vargas A, A.; Gallardo R, I.; Cruz G, M.; Amador C, C.

    2014-10-01

    The earthquake followed by a tsunami, happened in March, 2011 in the coasts of oriental Japan, caused damages in the nuclear power plants 1 at 4 of Fukushima Daiichi leading to damage of the fuel in three of the reactors and to the radiation liberation to the exterior. As consequence of those events, the regulations requires that the power plants with Primary Containment type Mark I and II evaluate to have a system of rigid vent with a monitoring equipment of radiation effluents. The present work covers the rigid vent of diameter 12 of the Primary Containment, type Mark-II, of nuclear power plant of Laguna Verde in conditions of severe accident and normal operation, low regime of Extended Power Up rate (EPU - 2317 MWt), using the codes MAAP3B, MICROSHILED 5.05 and the Bardach Black Boxes methodology. As a result the measurement range of the radiation monitor that is required for monitoring the gassy liberation to the atmosphere was determined. The conclusion is that the superior limit of the range of the radiation meter during a Severe Accident is of 8.55 E + 05 R/h (8.55 E + 08 m R/h) and the superior limit in normal operation of 1.412 E-11 at 2.540 E-7 R/h (1.412 E-14 at 2.540 E-10 m R/h). (Author)

  2. Simultaneous intra-arterial chemotherapy and radiotherapy for carcinoma of oropharynx without neck metastasis

    International Nuclear Information System (INIS)

    Tomita, Kichinobu; Higaki, Yuichiro

    2000-01-01

    We evaluated the usefulness of simultaneous intra-arterial chemotherapy and radiotherapy for oropharyngeal cancer without neck metastasis. Fifty eight cases without neck metastasis out of previously untreated 117 patients with oropharyngeal cancer treated at National Kyushu Cancer Center from 1972 to 1995 were examined. Seventeen patients were in T1, 27 in T2, 10 in T3, 4 in T4. Fourteen patients of 58 patients were treated by simultaneous intra-arterial chemotherapy and radiation therapy. The 5-year survival rate by Kaplan-Meier method for intra-arterial infusion group and non intra-arterial infusion group were 86% and 71%, respectively. Thirty one patients were treated with irradiation without surgery. In 31 cases without surgery, the 5-year survival rate for intra-arterial infusion group (13 cases) was 85%, while that for non intra-arterial infusion group (18 cases) was 60%, and the local control rate for intra-arterial infusion group is 92%, while that for non intra-arterial infusion group was 56%. Simultaneous intra-arterial chemotherapy and radiotherapy for oropharyngeal cancer without neck metastasis is useful to improve the prognosis with preserving the function. (author)

  3. Analgesic efficacy of intracapsular and intra-articular local anaesthesia for knee arthroplasty

    DEFF Research Database (Denmark)

    Andersen, L Ø; Husted, H; Kristensen, B B

    2010-01-01

    The optimal site for wound delivery of local anaesthetic after total knee arthroplasty is undetermined. Sixty patients having total knee arthroplasty received intra-operative infiltration analgesia with ropivacaine 0.2% and were then were randomly assigned to receive either intracapsular or intra...

  4. Non-Invasive Monitoring of Intra-Abdominal Bleeding Rate Using Electrical Impedance Tomography

    Science.gov (United States)

    2009-09-01

    for intra-abdominal bleeding are either impractical for field use (MRI/CT), non-specific (pulse, blood pressure) operator dependent (ultrasound/ DPL ...or invasive ( DPL ) Thus, EIT is a potentially highly sensitive and useful technique for detecting and monitoring intra- abdominal bleeding. The aim of

  5. Guidelines for target volume definition in post-operative radiotherapy for prostate cancer, on behalf of the EORTC Radiation Oncology Group

    International Nuclear Information System (INIS)

    Poortmans, Philip; Bossi, Alberto; Vandeputte, Katia; Bosset, Mathieu; Miralbell, Raymond; Maingon, Philippe; Boehmer, Dirk; Budiharto, Tom; Symon, Zvi; Bergh, Alfons C.M. van den; Scrase, Christopher; Poppel, Hendrik van; Bolla, Michel

    2007-01-01

    The appropriate application of 3-D conformal radiotherapy, intensity modulated radiotherapy or image guided radiotherapy for patients undergoing post-operative radiotherapy for prostate cancer requires a standardisation of the target volume definition and delineation as well as standardisation of the clinical quality assurance procedures. Recommendations for this are presented on behalf of the European Organisation for Research and Treatment of Cancer (EORTC) Radiation Oncology Group and in addition to the already published guidelines for radiotherapy as the primary treatment

  6. Radiation dose to construction workers at operating nuclear power plant sites. Volume 2. Appendices A--F. Final report, September 1975--September 1978

    Energy Technology Data Exchange (ETDEWEB)

    Endres, G.W.R.; Shipler, D.B.

    1978-12-01

    These appendices contain the dosimetry procedures and details of the personnel and environmental dosimeters used for the Radiation Dose to Construction Workers at Operating Nuclear Power Plant Sites Study. A printout of the computer codes used to analyze dosimeter data is included along with all the raw data obtained. Appendices C through F contain computer output and log-normal plots of dosimetry data for environmental location and construction worker groups.

  7. A modular approach for assessing the effect of radiation environments on man in operational systems. The radiobiological vulnerability of man during task performance

    Science.gov (United States)

    Ewing, D. E.

    1972-01-01

    A modular approach for assessing the affects of radiation environments on man in operational systems has been developed. The feasibility of the model has been proved and the practicality has been assessed. It has been applied to one operational system to date and information obtained has been submitted to systems analysts and mission planners for the assessment of man's vulnerability and impact on systems survivability. In addition, the model has been developed so that the radiobiological data can be input to a sophisticated man-machine interface model to properly relate the radiobiological stress with other mission stresses including the effects of a degraded system.

  8. Quantification of the impact of multifaceted initiatives intended to improve operational efficiency and the safety culture: a case study from an academic medical center radiation oncology department.

    Science.gov (United States)

    Chera, Bhishamjit S; Mazur, Lukasz; Jackson, Marianne; Taylor, Kinely; Mosaly, Prithima; Chang, Sha; Deschesne, Kathy; LaChapelle, Dana; Hoyle, Lesley; Saponaro, Patricia; Rockwell, John; Adams, Robert; Marks, Lawrence B

    2014-01-01

    We have systematically been incorporating several operational efficiency and safety initiatives into our academic radiation oncology clinic. We herein quantify the impact of these initiatives on prospectively collected, clinically meaningful, metrics. The data from 5 quality improvement initiatives, each focused on a specific safety/process concern in our clinic, are presented. Data was collected prospectively: operational metrics recorded before and after implementation of the initiative were compared using statistical analysis. Results from the Agency for Health Care Research and Quality (AHRQ) patient safety culture surveys administered during and after many of these initiatives were similarly compared. (1) Workload levels for nurses assisting with brachytherapy were high (National Aeronautics and Space Administration Task Load Index (NASA-TLX) scores >55-60, suggesting, "overwork"). Changes in work flow and procedure room layout reduced workload to more acceptable levels (NASA-TLX 50% to safety culture," we conducted a pre- and postanalysis using the AHRQ survey. Improvements in all measured dimensions were noted. Quality improvement initiatives can be successfully implemented in an academic radiation oncology department to yield measurable improvements in operations resulting in improvement in patient safety culture. Copyright © 2014 American Society for Radiation Oncology. Published by Elsevier Inc. All rights reserved.

  9. Comparação entre o teste de despertar e a monitoração neurofisiológica intra-operatória com potencial evocado somato-sensitivo nas cirurgias de escoliose Comparación entre el teste de despertar y la monitorización neurofisiológica intraoperatoria con potencial evocado somato sensorial en las cirugías de escoliosis Comparison between the wake-up test and the intra-operative neurophysiologic monitoring with somato-sensitive evoked potentials in surgery for scoliosis

    Directory of Open Access Journals (Sweden)

    Eduardo Barros Puertas

    2009-03-01

    , entre el período de enero de 1985 ha mayo de 2001. Los procedimientos fueron divididos en dos grupos, siendo 80 pacientes operados sin monitoración intra-operatória, utilizado la prueba del despertar, en el período de enero de 1985 a enero de 1998. A partir de mayo de 1998 las cirugías comenzaron a ser supervisadas con monitoración del potencial evocado somato-sensitivo (PESS para la prevención de lesión neurológica, formando así un segundo grupo de 31 pacientes. RESULTADOS: en el primer grupo, un paciente presento lesión neurológica irreversible y cuatro pacientes tuvieron lesión neurológica reversible. Entre los 31 pacientes, com monitoración neurofisiológica somato sensitiva, ocho pacientes presentaron lesión neurológica reversible evidenciada en el intra-operatório, sin ninguna repercusión clínica después del procedimiento. CONCLUSIÓN: los actuales resultados sugieren la eficacia de la monitoración intra-operatória, con el potencial evocado somato-sensitivo, para la prevención de lesiones neurológicas, en las cirugías correctivas de curvas rígidas de escoliosis idiopática.OBJECTIVE: the objective of this study is to compare the incidence of neurological injuries in corrective surgeries for rigid curves of idiopathic scoliosis using only the wake-up test and using the intraoperative neurophysiologic monitoring with somato sensitive evoked potentials. METHODS: we performed 111 surgeries to correct idiopathic scoliosis, with rigid curves through instrumentation and posterior fusion in the period January 1985 to May 2001. The procedures were divided into two groups, with 80 patients operated without the intra-operative monitoring, using only the wake-up test, from January 1985 to January 1998. From May 1998 the surgeries began to be monitored with somato-sensitive evoked potential (PESS for prevention of neurological damage, forming a second group of 31 patients. RESULTS: in the first group, one patient had irreversible neurological damage

  10. Organization and operation of the sixth international symposium on the natural radiation environment (NRE VI). Final report

    International Nuclear Information System (INIS)

    Hopke, P.K.

    1995-01-01

    An important source of human exposure to radiation is the natural world including cosmic rays, cosmogonic radionuclides, natural terrestrial radionuclides, and radon isotopes and its decay products. Considerable effort is being expended on a worldwide basis to characterize the exposure to the natural radiation environment and determine the important pathways for the exposure to result in dose to tissue that leads to injury and disease. The problem of background exposure to naturally occurring radioactivity has been the subject of research since the initial discovery of the radioactivity of uranium and thorium. However, with the advent of artificial sources of radiation with both benefits (medical x-rays and nuclear medicine), and harm (Chernobyl fallout), the nature and magnitude of the natural radiation environment and the effects on various populations are important in the development of overall public health strategies as ALARA principles are applied. To facilitate the exchange of information and the review of uncertainties and scientific research priorities, a series of 5 international meetings on Natural Radiation Environment, 1963, 1987, 1991. This conference (Montreal, 1995) covers the range of natural radiation environments that give rise to human exposure and dose. This document is a program summary

  11. Lasers with intra-cavity phase elements

    Science.gov (United States)

    Gulses, A. Alkan; Kurtz, Russell; Islas, Gabriel; Anisimov, Igor

    2018-02-01

    Conventional laser resonators yield multimodal output, especially at high powers and short cavity lengths. Since highorder modes exhibit large divergence, it is desirable to suppress them to improve laser quality. Traditionally, such modal discriminations can be achieved by simple apertures that provide absorptive loss for large diameter modes, while allowing the lower orders, such as the fundamental Gaussian, to pass through. However, modal discrimination may not be sufficient for short-cavity lasers, resulting in multimodal operation as well as power loss and overheating in the absorptive part of the aperture. In research to improve laser mode control with minimal energy loss, systematic experiments have been executed using phase-only elements. These were composed of an intra-cavity step function and a diffractive out-coupler made of a computer-generated hologram. The platform was a 15-cm long solid-state laser that employs a neodymium-doped yttrium orthovanadate crystal rod, producing 1064 nm multimodal laser output. The intra-cavity phase elements (PEs) were shown to be highly effective in obtaining beams with reduced M-squared values and increased output powers, yielding improved values of radiance. The utilization of more sophisticated diffractive elements is promising for more difficult laser systems.

  12. Single mode operation of a tea CO2 laser by a CW CO2 laser radiation injection

    International Nuclear Information System (INIS)

    Silakhori, K.; Soltanmoradi, F.; Behjat, A.; Montazerghaem, M.; Sadr, R.

    2005-01-01

    In this research work, single mode operation based on injection of a CW laser beam into TEA CO 2 laser cavity has been demonstrated. The technique has vast applications in research programs for laser spectroscopy and optical pumping. The observed smooth pulse shapes indicated that the system is operating in a single mode of operation, where no additional PZT mounted elements or other cavity stabilizing devices have been used. In addition, it have been observed that the output energy has not been reduced when the laser was operating in a single mode of operation, compared with the case when the laser is operating in the multi-mode regime

  13. Radiation exposure to operating staff during rotational flat-panel angiography and C-arm cone beam computed tomography (CT) applications.

    Science.gov (United States)

    Schulz, Boris; Heidenreich, Ralf; Heidenreich, Monika; Eichler, Katrin; Thalhammer, Axel; Naeem, Naguib Nagy Naguib; Vogl, Thomas Josef; Zangos, Stefan

    2012-12-01

    To evaluate the radiation exposure for operating personnel associated with rotational flat-panel angiography and C-arm cone beam CT. Using a dedicated angiography-suite, 2D and 3D examinations of the liver were performed on a phantom to generate scattered radiation. Exposure was measured with a dosimeter at predefined heights (eye, thyroid, breast, gonads and knee) at the physician's location. Analysis included 3D procedures with a field of view (FOV) of 24 cm × 18 cm (8s/rotation, 20s/rotation and 5s/2 rotations), and 47 cm×18 cm (16s/2 rotations) and standard 2D angiography (10s, FOV 24 cm×18 cm). Measurements showed the highest radiation dose at the eye and thyroid level. In comparison to 2D-DSA (3.9 μSv eye-exposure), the 3D procedures caused an increased radiation exposure both in standard FOV (8s/rotation: 28.0 μSv, 20s/rotation: 79.3 μSv, 5s/2 rotations: 32.5 μSv) and large FOV (37.6 μSv). Proportional distributions were measured for the residual heights. With the use of lead glass, irradiation of the eye lens was reduced to 0.2 μSv (2D DSA) and 10.6 μSv (3D technique with 20s/rotation). Rotational flat-panel angiography and C-arm cone beam applications significantly increase radiation exposure to the attending operator in comparison to 2D angiography. Our study indicates that the physician should wear protective devices and leave the examination room when performing 3D examinations. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  14. Radiation exposure to operating staff during rotational flat-panel angiography and C-arm cone beam computed tomography (CT) applications

    Energy Technology Data Exchange (ETDEWEB)

    Schulz, Boris, E-mail: boris.schell@googlemail.com [Goethe University Hospital, Department of Diagnostic and Interventional Radiology, Theodor-Stern-Kai 7, 60590 Frankfurt (Germany); Heidenreich, Ralf, E-mail: ralf.heidenreich@roentgen-consult.de [Röntgen-Consult Company, Schulhausstrasse 37, 79199 Kirchzarten (Germany); Heidenreich, Monika, E-mail: info@roentgen-consult.de [Röntgen-Consult Company, Schulhausstrasse 37, 79199 Kirchzarten (Germany); Eichler, Katrin, E-mail: k.eichler@em.uni-frankfurt.de [Goethe University Hospital, Department of Diagnostic and Interventional Radiology, Theodor-Stern-Kai 7, 60590 Frankfurt (Germany); Thalhammer, Axel, E-mail: axel.thalhammer@kgu.de [Goethe University Hospital, Department of Diagnostic and Interventional Radiology, Theodor-Stern-Kai 7, 60590 Frankfurt (Germany); Naeem, Naguib Nagy Naguib, E-mail: nagynnn@yahoo.com [Goethe University Hospital, Department of Diagnostic and Interventional Radiology, Theodor-Stern-Kai 7, 60590 Frankfurt (Germany); Vogl, Thomas Josef, E-mail: T.Vogl@em.uni-frankfurt.de [Goethe University Hospital, Department of Diagnostic and Interventional Radiology, Theodor-Stern-Kai 7, 60590 Frankfurt (Germany); Zangos, Stefan, E-mail: Zangos@em.uni-frankfurt.de [Goethe University Hospital, Department of Diagnostic and Interventional Radiology, Theodor-Stern-Kai 7, 60590 Frankfurt (Germany)

    2012-12-15

    Purpose: To evaluate the radiation exposure for operating personel associated with rotational flat-panel angiography and C-arm cone beam CT. Materials and methods: Using a dedicated angiography-suite, 2D and 3D examinations of the liver were performed on a phantom to generate scattered radiation. Exposure was measured with a dosimeter at predefined heights (eye, thyroid, breast, gonads and knee) at the physician's location. Analysis included 3D procedures with a field of view (FOV) of 24 cm × 18 cm (8 s/rotation, 20 s/rotation and 5 s/2 rotations), and 47 cm × 18 cm (16 s/2 rotations) and standard 2D angiography (10 s, FOV 24 cm × 18 cm). Results: Measurements showed the highest radiation dose at the eye and thyroid level. In comparison to 2D-DSA (3.9 μSv eye-exposure), the 3D procedures caused an increased radiation exposure both in standard FOV (8 s/rotation: 28.0 μSv, 20 s/rotation: 79.3 μSv, 5 s/2 rotations: 32.5 μSv) and large FOV (37.6 μSv). Proportional distributions were measured for the residual heights. With the use of lead glass, irradiation of the eye lens was reduced to 0.2 μSv (2D DSA) and 10.6 μSv (3D technique with 20 s/rotation). Conclusion: Rotational flat-panel angiography and C-arm cone beam applications significantly increase radiation exposure to the attending operator in comparison to 2D angiography. Our study indicates that the physician should wear protective devices and leave the examination room when performing 3D examinations.

  15. Medulloblastoma: Conventional Radiation Therapy in Comparison to Chemo Radiation Therapy in The Post-operative Treatment of High-Risk Patients

    International Nuclear Information System (INIS)

    Abd El-Aal, H.H.; Mokhtar, M.M.; Habib, E.E.; El-Kashef, A.T.; Fahmy, E.S.

    2005-01-01

    The aim of this study is to assess treatment results of 48 pediatric high-risk medulloblastoma cases that were treated by surgery, radiotherapy with or without chemotherapy. The impact of adjuvant combination chemotherapy on treatment results will be assessed. Forty-eight cases of pediatric high-risk medulloblastoma treated from July 2001 to July 2004 were randomized into two groups. The first (group I) included 21 patients who received postoperative craniospinal radiation therapy (36 Gy + boost 20 Gy to the posterior fossa). The second (group II) included 27 cases who received postoperative combination cranio-spinal radiation therapy (with the same dose as the first group) and chemotherapy (vincristine, etoposide, cisplatin). Both groups were compared as regards overall survival (OS), disease free survival (DFS), response rate and treatment toxicity. In-group I, complete remission (CR) was achieved in 71.4% of the cases; partial remission (PR) in 14.3% of the patients; stationary disease (SD) in 14.3% and none of the cases suffered from progressive disease. The three year OS was 69.5% and the three-year OFS was 61.3%. In-group II, CR was achieved in 59.3% of the cases; PR in 3.7%; SO in 3.7% and PO in 37.3% of the cases. The three-year OS was 48.4% and the 3-year OFS was 48.9%. Regarding acute treatment toxicity in group I, nine patients (31.5%) developed grade I myelo-suppression and seven cases (24.5%) developed grade II myelo-suppression with three to five days treatment interruption. Whereas in group II, 13 patients (45.5%) developed grade I myelosuppression and seven cases (24.5%) developed grade II myelo-suppression requiring interruption of treatment for a period ranging from five to seven days with spontaneous recovery. In group I no other acute toxicity was recognized, whereas in group II other toxicities related to chemotherapy were noticed. For example, three patients (II %) developed peripheral neuritis during the course of treatment and two patients

  16. Analysis of Selected Photovoltaic Panels Operating Parameters as a Function of Partial Shading and Intensity of Reflected Radiation

    Directory of Open Access Journals (Sweden)

    Bilčík Matúš

    2018-03-01

    Full Text Available Due to expansion of utilisation of photovoltaics in ordinary households, the question arises how this phenomenon affects the electric power of photovoltaic modules. The article deals with the electric power analysis of photovoltaic modules as a function of two very important factors. The first examined factor was partial shading, and the second factor was the intensity of reflected radiation. In order to determine the dependence of module power on the aforementioned parameters, a measurement system under laboratory conditions has been prepared. For identification of the reflected radiation effect on the power of the photovoltaic module, a series of measurements was performed on 7 different surfaces with the same radiation source. It is evident from obtained experimental result that the ratio of reflected irradiation on the solar module power is 1.29%. By simulation of partial shading of photovoltaic module, the decrease of 86.15% in its output power was identified.

  17. Environmental assessment model for shallow land disposal of low-level radioactive wastes: interim report. [PRESTO (Prediction of Radiation Effects from Shallow Trench Operations)

    Energy Technology Data Exchange (ETDEWEB)

    Little, C.A.; Fields, D.E.; Emerson, C.J.; Hiromoto, G.

    1981-09-01

    PRESTO (Prediction of Radiation Effects from Shallow Trench Operations) is a computer code developed under US Environmental Protection Agency (EPA) funding to evaluate possible health effects from shallow land burial trenches. The model is intended to be generic and to assess radionuclide transport, ensuing exposure, and health impact to a static local population for a 1000-y period following the end of burial operations. Human exposure scenarios considered by the model include normal releases (including leaching and operational spillage), human intrusion, and site farming or reclamation. Pathways and processes of transit from the trench to an individual or population include: groundwater transport, overland flow, erosion, surface water dilution, resuspension, atmospheric transport, deposition, inhalation, and ingestion of contaminated beef, milk, crops, and water. Both population doses and individual doses are calculated as well as doses to the intruder and farmer.

  18. Operational accidents and radiation exposure experience within the United States Atomic Energy Commission, 1943--1975. [AEC health and safety during first 32 years

    Energy Technology Data Exchange (ETDEWEB)

    1975-01-01

    The occupational injury and fatality experience during 32 years of the development of the atomic energy industry under the direction of the Atomic Energy Commission (AEC) and its predecessor, the Manhattan Engineering District, is reviewed. Data are included on the cause of all accidents, including fires and transportation accidents, and the cost of AEC property damage. Fatalities of AEC and contractor personnel from all causes during the 32-year period totaled 321, of which 184 occurred in construction; 121 in AEC operations such as production, research, and services; and 16 in Government functions. There were 19,225 lost-time injuries attributable to all accidental causes, or a 32-year frequency rate of 2.75 based on the number of injuries per million man-hours. There were six deaths attributable to nuclear causes, thee of which were due to blast and flying missiles and three caused by whole-body radiation exposure. Forty-one workers were involved in lost-time radiation accidents, of whom 26 showed clinical manifestations attributable to radiation, resulting in permanent partial-disability of three workers and the loss of a digit by four workers, while the others did not develop evidence of radiation injury. (CH)

  19. Study of radiation exposure rate on the measurement points in Kartini reactor hall as based to determine operation safety parameters (KBO)